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Network neighborhood for query Sequence : WDHD1_MOUSE

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WDHD1_MOUSE
SwissProt Accessions	P59328, Q6P408	Gene names	Wdhd1, And1
Domain Architecture	No domain graphic available
Description	WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA- binding protein 1) (And-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

WDHD1_HUMAN
θ value	0 (rank : 1)	NC score	0.961940 (rank : 2)
Query Neighborhood Hits	414	Target Neighborhood Hits	342	Shared Neighborhood Hits	259
SwissProt Accessions	O75717	Gene names	WDHD1, AND1
Domain Architecture
Description	WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA- binding protein 1) (And-1).

WDHD1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	414	Target Neighborhood Hits	414	Shared Neighborhood Hits	414
SwissProt Accessions	P59328, Q6P408	Gene names	Wdhd1, And1
Domain Architecture	No domain graphic available
Description	WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA- binding protein 1) (And-1).

WDR5_HUMAN
θ value	1.29331e-14 (rank : 3)	NC score	0.719423 (rank : 3)
Query Neighborhood Hits	414	Target Neighborhood Hits	341	Shared Neighborhood Hits	255
SwissProt Accessions	P61964, Q91VA5, Q9NWX7, Q9UGP9	Gene names	WDR5, BIG3
Domain Architecture
Description	WD repeat protein 5 (BMP2-induced 3-kb gene protein).

WDR5_MOUSE
θ value	1.29331e-14 (rank : 4)	NC score	0.719423 (rank : 4)
Query Neighborhood Hits	414	Target Neighborhood Hits	341	Shared Neighborhood Hits	255
SwissProt Accessions	P61965, Q91VA5, Q922C9, Q9NWX7, Q9UGP9	Gene names	Wdr5, Big, Big3
Domain Architecture
Description	WD repeat protein 5 (BMP2-induced 3-kb gene protein) (WD repeat protein BIG-3).

A16L1_HUMAN
θ value	3.52202e-12 (rank : 5)	NC score	0.674763 (rank : 45)
Query Neighborhood Hits	414	Target Neighborhood Hits	664	Shared Neighborhood Hits	256
SwissProt Accessions	Q676U5, Q6IPN1, Q6UXW4, Q6ZVZ5, Q8NCY2, Q96JV5, Q9H619	Gene names	ATG16L1, APG16L
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 16-1 (APG16-like 1).

WDR39_HUMAN
θ value	2.28291e-11 (rank : 6)	NC score	0.712251 (rank : 5)
Query Neighborhood Hits	414	Target Neighborhood Hits	296	Shared Neighborhood Hits	239
SwissProt Accessions	O76071	Gene names	WDR39, CIAO1
Domain Architecture
Description	WD repeat protein 39 (Ciao 1 protein).

A16L1_MOUSE
θ value	2.98157e-11 (rank : 7)	NC score	0.656052 (rank : 56)
Query Neighborhood Hits	414	Target Neighborhood Hits	776	Shared Neighborhood Hits	260
SwissProt Accessions	Q8C0J2, Q6KAT7, Q80U97, Q80U98, Q80U99, Q80Y53, Q9DB63	Gene names	Atg16l1, Apg16l
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 16-1 (APG16-like 1).

APAF_MOUSE
θ value	3.89403e-11 (rank : 8)	NC score	0.699325 (rank : 19)
Query Neighborhood Hits	414	Target Neighborhood Hits	343	Shared Neighborhood Hits	257
SwissProt Accessions	O88879	Gene names	Apaf1
Domain Architecture
Description	Apoptotic protease-activating factor 1 (Apaf-1).

WDR57_HUMAN
θ value	6.64225e-11 (rank : 9)	NC score	0.703522 (rank : 9)
Query Neighborhood Hits	414	Target Neighborhood Hits	322	Shared Neighborhood Hits	250
SwissProt Accessions	Q96DI7, O75938, O95320	Gene names	WDR57, PRP8BP, SFP38
Domain Architecture	No domain graphic available
Description	WD repeat protein 57 (Prp8-binding protein) (hPRP8BP) (U5 snRNP- specific 40 kDa protein) (38 kDa-splicing factor).

WDR57_MOUSE
θ value	6.64225e-11 (rank : 10)	NC score	0.704268 (rank : 7)
Query Neighborhood Hits	414	Target Neighborhood Hits	323	Shared Neighborhood Hits	250
SwissProt Accessions	Q6PE01, Q3TEJ3, Q9DCX3	Gene names	Wdr57
Domain Architecture	No domain graphic available
Description	WD repeat protein 57.

TAF5L_MOUSE
θ value	1.133e-10 (rank : 11)	NC score	0.697113 (rank : 24)
Query Neighborhood Hits	414	Target Neighborhood Hits	337	Shared Neighborhood Hits	252
SwissProt Accessions	Q91WQ5, Q8BTL5	Gene names	Taf5l, Paf65b
Domain Architecture
Description	TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65- beta).

TAF5L_HUMAN
θ value	7.34386e-10 (rank : 12)	NC score	0.694951 (rank : 27)
Query Neighborhood Hits	414	Target Neighborhood Hits	330	Shared Neighborhood Hits	253
SwissProt Accessions	O75529, Q8IW31	Gene names	TAF5L, PAF65B
Domain Architecture
Description	TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65- beta).

TAF5_HUMAN
θ value	7.34386e-10 (rank : 13)	NC score	0.696016 (rank : 26)
Query Neighborhood Hits	414	Target Neighborhood Hits	352	Shared Neighborhood Hits	253
SwissProt Accessions	Q15542, Q86UZ7, Q9Y4K5	Gene names	TAF5, TAF2D
Domain Architecture
Description	Transcription initiation factor TFIID subunit 5 (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100).

TBL1R_HUMAN
θ value	9.59137e-10 (rank : 14)	NC score	0.701933 (rank : 14)
Query Neighborhood Hits	414	Target Neighborhood Hits	327	Shared Neighborhood Hits	260
SwissProt Accessions	Q9BZK7, Q9H2I1, Q9H9A1	Gene names	TBL1XR1, IRA1, TBLR1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1XR1 (Transducin beta-like 1X-related protein 1) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1).

TBL1R_MOUSE
θ value	9.59137e-10 (rank : 15)	NC score	0.702150 (rank : 13)
Query Neighborhood Hits	414	Target Neighborhood Hits	329	Shared Neighborhood Hits	260
SwissProt Accessions	Q8BHJ5, Q3UWL6, Q8CBG4, Q8VEG3, Q9EQD4	Gene names	Tbl1xr1, Ira1, Tblr1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1XR1 (Transducin beta-like 1X-related protein 1) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1).

TBL1X_HUMAN
θ value	1.25267e-09 (rank : 16)	NC score	0.702645 (rank : 10)
Query Neighborhood Hits	414	Target Neighborhood Hits	329	Shared Neighborhood Hits	258
SwissProt Accessions	O60907, Q86UY2	Gene names	TBL1X, TBL1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1X (Transducin beta-like 1X protein) (Transducin-beta-like 1, X-linked) (SMAP55).

PWP2_MOUSE
θ value	1.63604e-09 (rank : 17)	NC score	0.681535 (rank : 38)
Query Neighborhood Hits	414	Target Neighborhood Hits	309	Shared Neighborhood Hits	239
SwissProt Accessions	Q8BU03, Q8BTR0	Gene names	Pwp2h
Domain Architecture
Description	Periodic tryptophan protein 2 homolog.

TAF5_MOUSE
θ value	1.63604e-09 (rank : 18)	NC score	0.694427 (rank : 29)
Query Neighborhood Hits	414	Target Neighborhood Hits	366	Shared Neighborhood Hits	254
SwissProt Accessions	Q8C092, Q8BTR2	Gene names	Taf5
Domain Architecture
Description	Transcription initiation factor TFIID subunit 5 (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100).

WD51B_HUMAN
θ value	2.13673e-09 (rank : 19)	NC score	0.704941 (rank : 6)
Query Neighborhood Hits	414	Target Neighborhood Hits	335	Shared Neighborhood Hits	255
SwissProt Accessions	Q8TC44	Gene names	WDR51B
Domain Architecture	No domain graphic available
Description	WD repeat protein 51B.

APAF_HUMAN
θ value	3.64472e-09 (rank : 20)	NC score	0.692812 (rank : 31)
Query Neighborhood Hits	414	Target Neighborhood Hits	334	Shared Neighborhood Hits	252
SwissProt Accessions	O14727, O43297, Q7Z438, Q9BXZ6, Q9UBZ5, Q9UGN8, Q9UGN9, Q9UGP0, Q9UJ58, Q9UJ59, Q9UJ60, Q9UJ61, Q9UJ62, Q9UJ63, Q9UJ64, Q9UJ65, Q9UJ66, Q9UJ67, Q9UNC9	Gene names	APAF1, KIAA0413
Domain Architecture
Description	Apoptotic protease-activating factor 1 (Apaf-1).

TBLX_MOUSE
θ value	3.64472e-09 (rank : 21)	NC score	0.701712 (rank : 15)
Query Neighborhood Hits	414	Target Neighborhood Hits	335	Shared Neighborhood Hits	260
SwissProt Accessions	Q9QXE7, Q8BMM0, Q8BYQ4, Q8C0A1	Gene names	Tbl1x, Tbl1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1X (Transducin beta-like 1X protein).

PRP19_MOUSE
θ value	6.21693e-09 (rank : 22)	NC score	0.694799 (rank : 28)
Query Neighborhood Hits	414	Target Neighborhood Hits	335	Shared Neighborhood Hits	253
SwissProt Accessions	Q99KP6, Q3TP64, Q8BKZ5, Q8BVQ4	Gene names	Prpf19, Prp19, Snev
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor 19 (PRP19/PSO4 homolog) (Nuclear matrix protein 200) (Nuclear matrix protein SNEV).

PRP19_HUMAN
θ value	8.11959e-09 (rank : 23)	NC score	0.694373 (rank : 30)
Query Neighborhood Hits	414	Target Neighborhood Hits	333	Shared Neighborhood Hits	252
SwissProt Accessions	Q9UMS4	Gene names	PRPF19, NMP200, PRP19
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor 19 (PRP19/PSO4 homolog) (Nuclear matrix protein 200) (hPso4).

WDR69_HUMAN
θ value	8.11959e-09 (rank : 24)	NC score	0.699931 (rank : 18)
Query Neighborhood Hits	414	Target Neighborhood Hits	324	Shared Neighborhood Hits	248
SwissProt Accessions	Q8N136, Q6ZRY1, Q8N776	Gene names	WDR69
Domain Architecture	No domain graphic available
Description	WD repeat protein 69.

PWP2_HUMAN
θ value	1.38499e-08 (rank : 25)	NC score	0.679619 (rank : 41)
Query Neighborhood Hits	414	Target Neighborhood Hits	309	Shared Neighborhood Hits	243
SwissProt Accessions	Q15269, Q96A77	Gene names	PWP2H, PWP2
Domain Architecture
Description	Periodic tryptophan protein 2 homolog.

SPG16_HUMAN
θ value	1.80886e-08 (rank : 26)	NC score	0.701301 (rank : 16)
Query Neighborhood Hits	414	Target Neighborhood Hits	361	Shared Neighborhood Hits	248
SwissProt Accessions	Q8N0X2, Q658W1, Q68DB3, Q6I9Z6, Q8N9C7, Q9H601	Gene names	SPAG16, PF20
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 16 protein (PF20 protein homolog).

SPG16_MOUSE
θ value	1.80886e-08 (rank : 27)	NC score	0.704181 (rank : 8)
Query Neighborhood Hits	414	Target Neighborhood Hits	377	Shared Neighborhood Hits	253
SwissProt Accessions	Q8K450, Q8C450, Q9CPU8, Q9D522	Gene names	Spag16, Pf20
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 16 protein (PF20 protein homolog).

TBL1Y_HUMAN
θ value	2.36244e-08 (rank : 28)	NC score	0.700832 (rank : 17)
Query Neighborhood Hits	414	Target Neighborhood Hits	331	Shared Neighborhood Hits	258
SwissProt Accessions	Q9BQ87	Gene names	TBL1Y, TBL1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1Y (Transducin beta-like 1Y protein) (Transducin-beta-like 1, Y-linked).

WD51A_HUMAN
θ value	2.36244e-08 (rank : 29)	NC score	0.698647 (rank : 21)
Query Neighborhood Hits	414	Target Neighborhood Hits	337	Shared Neighborhood Hits	252
SwissProt Accessions	Q8NBT0, Q2TAK6, Q96IK6, Q9UFJ8	Gene names	WDR51A
Domain Architecture	No domain graphic available
Description	WD repeat protein 51A.

WD51B_MOUSE
θ value	2.36244e-08 (rank : 30)	NC score	0.698998 (rank : 20)
Query Neighborhood Hits	414	Target Neighborhood Hits	321	Shared Neighborhood Hits	257
SwissProt Accessions	Q8BHD1	Gene names	Wdr51b
Domain Architecture	No domain graphic available
Description	WD repeat protein 51B.

KTNB1_HUMAN
θ value	4.0297e-08 (rank : 31)	NC score	0.689205 (rank : 32)
Query Neighborhood Hits	414	Target Neighborhood Hits	349	Shared Neighborhood Hits	256
SwissProt Accessions	Q9BVA0, O60620	Gene names	KATNB1
Domain Architecture	No domain graphic available
Description	Katanin p80 WD40-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin).

KTNB1_MOUSE
θ value	4.0297e-08 (rank : 32)	NC score	0.688956 (rank : 33)
Query Neighborhood Hits	414	Target Neighborhood Hits	356	Shared Neighborhood Hits	255
SwissProt Accessions	Q8BG40, Q8CD18, Q8R1J0, Q9CWV2	Gene names	Katnb1
Domain Architecture	No domain graphic available
Description	Katanin p80 WD40-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin).

LIS1_HUMAN
θ value	4.0297e-08 (rank : 33)	NC score	0.702503 (rank : 11)
Query Neighborhood Hits	414	Target Neighborhood Hits	333	Shared Neighborhood Hits	249
SwissProt Accessions	P43034, Q8WZ88, Q8WZ89	Gene names	PAFAH1B1, LIS1, MDCR, PAFAHA
Domain Architecture
Description	Platelet-activating factor acetylhydrolase IB subunit alpha (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1).

LIS1_MOUSE
θ value	4.0297e-08 (rank : 34)	NC score	0.702450 (rank : 12)
Query Neighborhood Hits	414	Target Neighborhood Hits	336	Shared Neighborhood Hits	249
SwissProt Accessions	P63005, O35592, P43035, P81692, Q9R2A6	Gene names	Pafah1b1, Lis-1, Lis1, Pafaha
Domain Architecture	No domain graphic available
Description	Platelet-activating factor acetylhydrolase IB subunit alpha (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1).

WD51A_MOUSE
θ value	5.26297e-08 (rank : 35)	NC score	0.698331 (rank : 22)
Query Neighborhood Hits	414	Target Neighborhood Hits	342	Shared Neighborhood Hits	257
SwissProt Accessions	Q8JZX3, Q9CY09	Gene names	Wdr51a
Domain Architecture	No domain graphic available
Description	WD repeat protein 51A.

WDR61_MOUSE
θ value	2.61198e-07 (rank : 36)	NC score	0.696974 (rank : 25)
Query Neighborhood Hits	414	Target Neighborhood Hits	331	Shared Neighborhood Hits	253
SwissProt Accessions	Q9ERF3, Q3U562, Q9CZP1	Gene names	Wdr61
Domain Architecture	No domain graphic available
Description	WD repeat protein 61 (Meiotic recombination REC14 protein homolog).

GBLP_HUMAN
θ value	4.45536e-07 (rank : 37)	NC score	0.687771 (rank : 35)
Query Neighborhood Hits	414	Target Neighborhood Hits	316	Shared Neighborhood Hits	246
SwissProt Accessions	P63244, P25388, P99049	Gene names	GNB2L1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein subunit beta 2-like 1 (Guanine nucleotide-binding protein subunit beta-like protein 12.3) (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase).

GBLP_MOUSE
θ value	4.45536e-07 (rank : 38)	NC score	0.687771 (rank : 36)
Query Neighborhood Hits	414	Target Neighborhood Hits	316	Shared Neighborhood Hits	246
SwissProt Accessions	P68040, P25388, P99049	Gene names	Gnb2l1, Gnb2-rs1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein subunit beta 2-like 1 (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) (p205) (12-3).

WDR61_HUMAN
θ value	4.45536e-07 (rank : 39)	NC score	0.697149 (rank : 23)
Query Neighborhood Hits	414	Target Neighborhood Hits	334	Shared Neighborhood Hits	255
SwissProt Accessions	Q9GZS3, Q6IA22, Q7Z4X4	Gene names	WDR61
Domain Architecture	No domain graphic available
Description	WD repeat protein 61 (Meiotic recombination REC14 protein homolog).

THOC3_HUMAN
θ value	5.81887e-07 (rank : 40)	NC score	0.678825 (rank : 42)
Query Neighborhood Hits	414	Target Neighborhood Hits	294	Shared Neighborhood Hits	239
SwissProt Accessions	Q96J01	Gene names	THOC3
Domain Architecture
Description	THO complex subunit 3 (Tho3) (TEX1 homolog).

THOC3_MOUSE
θ value	5.81887e-07 (rank : 41)	NC score	0.678368 (rank : 43)
Query Neighborhood Hits	414	Target Neighborhood Hits	296	Shared Neighborhood Hits	239
SwissProt Accessions	Q8VE80, Q9CWI8	Gene names	Thoc3
Domain Architecture
Description	THO complex subunit 3 (Tho3).

COPB2_HUMAN
θ value	9.92553e-07 (rank : 42)	NC score	0.653875 (rank : 60)
Query Neighborhood Hits	414	Target Neighborhood Hits	315	Shared Neighborhood Hits	244
SwissProt Accessions	P35606	Gene names	COPB2
Domain Architecture
Description	Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP) (p102).

COPB2_MOUSE
θ value	9.92553e-07 (rank : 43)	NC score	0.654053 (rank : 59)
Query Neighborhood Hits	414	Target Neighborhood Hits	315	Shared Neighborhood Hits	244
SwissProt Accessions	O55029, Q3U5Z9	Gene names	Copb2
Domain Architecture
Description	Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP) (p102).

FAN_HUMAN
θ value	1.29631e-06 (rank : 44)	NC score	0.547084 (rank : 153)
Query Neighborhood Hits	414	Target Neighborhood Hits	295	Shared Neighborhood Hits	230
SwissProt Accessions	Q92636	Gene names	NSMAF, FAN
Domain Architecture
Description	Protein FAN (Factor associated with N-SMase activation) (Factor associated with neutral sphingomyelinase activation).

SMU1_HUMAN
θ value	1.29631e-06 (rank : 45)	NC score	0.681003 (rank : 39)
Query Neighborhood Hits	414	Target Neighborhood Hits	311	Shared Neighborhood Hits	243
SwissProt Accessions	Q2TAY7, Q9BU59, Q9HA96, Q9NVD1	Gene names	SMU1
Domain Architecture	No domain graphic available
Description	Smu-1 suppressor of mec-8 and unc-52 protein homolog.

SMU1_MOUSE
θ value	1.29631e-06 (rank : 46)	NC score	0.681003 (rank : 40)
Query Neighborhood Hits	414	Target Neighborhood Hits	311	Shared Neighborhood Hits	243
SwissProt Accessions	Q3UKJ7, Q6PFR6, Q8BMY4, Q9D1I8, Q9JJ70	Gene names	Smu1
Domain Architecture	No domain graphic available
Description	Smu-1 suppressor of mec-8 and unc-52 protein homolog.

BRWD1_MOUSE
θ value	2.21117e-06 (rank : 47)	NC score	0.610464 (rank : 105)
Query Neighborhood Hits	414	Target Neighborhood Hits	478	Shared Neighborhood Hits	255
SwissProt Accessions	Q921C3, Q921C2	Gene names	Brwd1, Wdr9
Domain Architecture	No domain graphic available
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

BRWD1_HUMAN
θ value	2.88788e-06 (rank : 48)	NC score	0.605034 (rank : 113)
Query Neighborhood Hits	414	Target Neighborhood Hits	448	Shared Neighborhood Hits	250
SwissProt Accessions	Q9NSI6, O43721, Q5R2V0, Q5R2V1, Q8TCV3, Q96QG9, Q96QH0, Q9NUK1	Gene names	BRWD1, C21orf107, WDR9
Domain Architecture
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

AHI1_HUMAN
θ value	3.77169e-06 (rank : 49)	NC score	0.505176 (rank : 176)
Query Neighborhood Hits	414	Target Neighborhood Hits	537	Shared Neighborhood Hits	217
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

NLE1_HUMAN
θ value	3.77169e-06 (rank : 50)	NC score	0.688787 (rank : 34)
Query Neighborhood Hits	414	Target Neighborhood Hits	334	Shared Neighborhood Hits	261
SwissProt Accessions	Q9NVX2, O60868, Q9BU54	Gene names	NLE1
Domain Architecture
Description	Notchless homolog 1.

FAN_MOUSE
θ value	4.92598e-06 (rank : 51)	NC score	0.536223 (rank : 156)
Query Neighborhood Hits	414	Target Neighborhood Hits	292	Shared Neighborhood Hits	222
SwissProt Accessions	O35242	Gene names	Nsmaf, Fan
Domain Architecture
Description	Protein FAN (Factor associated with N-SMase activation) (Factor associated with neutral sphingomyelinase activation).

PRP17_MOUSE
θ value	4.92598e-06 (rank : 52)	NC score	0.666379 (rank : 51)
Query Neighborhood Hits	414	Target Neighborhood Hits	295	Shared Neighborhood Hits	231
SwissProt Accessions	Q9DC48	Gene names	Cdc40, Prp17
Domain Architecture
Description	Pre-mRNA-splicing factor PRP17 (Cell division cycle 40 homolog).

PK1IP_MOUSE
θ value	6.43352e-06 (rank : 53)	NC score	0.643088 (rank : 70)
Query Neighborhood Hits	414	Target Neighborhood Hits	313	Shared Neighborhood Hits	233
SwissProt Accessions	Q9DCE5, Q3UBK7, Q80UT4, Q8C5N6, Q923K2, Q9D3E9	Gene names	Pak1ip1
Domain Architecture	No domain graphic available
Description	p21-activated protein kinase-interacting protein 1 (PAK1-interacting protein 1) (Putative PAK inhibitor Skb15).

PRP4_HUMAN
θ value	6.43352e-06 (rank : 54)	NC score	0.671029 (rank : 48)
Query Neighborhood Hits	414	Target Neighborhood Hits	309	Shared Neighborhood Hits	245
SwissProt Accessions	O43172, O43445, O43864, Q96DG2, Q96IK4	Gene names	PRPF4, PRP4
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4) (hPrp4).

WDR33_HUMAN
θ value	6.43352e-06 (rank : 55)	NC score	0.596080 (rank : 121)
Query Neighborhood Hits	414	Target Neighborhood Hits	638	Shared Neighborhood Hits	258
SwissProt Accessions	Q9C0J8	Gene names	WDR33, WDC146
Domain Architecture
Description	WD repeat protein 33 (WD repeat protein WDC146).

FBXW7_HUMAN
θ value	8.40245e-06 (rank : 56)	NC score	0.657023 (rank : 54)
Query Neighborhood Hits	414	Target Neighborhood Hits	433	Shared Neighborhood Hits	253
SwissProt Accessions	Q969H0, Q96A16, Q96LE0, Q96RI2, Q9NUX6	Gene names	FBXW7, FBW7, FBX30, SEL10
Domain Architecture
Description	F-box/WD repeat protein 7 (F-box and WD-40 domain protein 7) (F-box protein FBX30) (hCdc4) (Archipelago homolog) (hAgo) (SEL-10).

FBXW7_MOUSE
θ value	8.40245e-06 (rank : 57)	NC score	0.657571 (rank : 53)
Query Neighborhood Hits	414	Target Neighborhood Hits	365	Shared Neighborhood Hits	248
SwissProt Accessions	Q8VBV4, Q8CCS5, Q8VHP4	Gene names	Fbxw7, Fbw7, Fbwd6, Fbxw6
Domain Architecture
Description	F-box/WD repeat protein 7 (F-box and WD-40 domain protein 7) (F-box protein FBW7) (F-box protein Fbxw6) (F-box-WD40 repeat protein 6) (SEL-10).

HIRA_HUMAN
θ value	1.09739e-05 (rank : 58)	NC score	0.609428 (rank : 110)
Query Neighborhood Hits	414	Target Neighborhood Hits	279	Shared Neighborhood Hits	230
SwissProt Accessions	P54198, Q8IXN2	Gene names	HIRA, DGCR1, HIR, TUPLE1
Domain Architecture
Description	HIRA protein (TUP1-like enhancer of split protein 1).

NLE1_MOUSE
θ value	1.09739e-05 (rank : 59)	NC score	0.686145 (rank : 37)
Query Neighborhood Hits	414	Target Neighborhood Hits	332	Shared Neighborhood Hits	260
SwissProt Accessions	Q8VEJ4	Gene names	Nle1
Domain Architecture
Description	Notchless homolog 1.

STRAP_MOUSE
θ value	1.09739e-05 (rank : 60)	NC score	0.675782 (rank : 44)
Query Neighborhood Hits	414	Target Neighborhood Hits	279	Shared Neighborhood Hits	233
SwissProt Accessions	Q9Z1Z2	Gene names	Strap, Unrip
Domain Architecture
Description	Serine-threonine kinase receptor-associated protein (UNR-interacting protein).

STRN3_HUMAN
θ value	1.09739e-05 (rank : 61)	NC score	0.590229 (rank : 123)
Query Neighborhood Hits	414	Target Neighborhood Hits	316	Shared Neighborhood Hits	228
SwissProt Accessions	Q13033, Q9NRA5	Gene names	STRN3, GS2NA, SG2NA
Domain Architecture
Description	Striatin-3 (Cell-cycle autoantigen SG2NA) (S/G2 antigen).

PRP17_HUMAN
θ value	1.43324e-05 (rank : 62)	NC score	0.663812 (rank : 52)
Query Neighborhood Hits	414	Target Neighborhood Hits	297	Shared Neighborhood Hits	232
SwissProt Accessions	O60508, O75471, Q9UPG1	Gene names	CDC40, PRP17
Domain Architecture
Description	Pre-mRNA-splicing factor PRP17 (hPRP17) (Cell division cycle 40 homolog) (EH-binding protein 3) (Ehb3).

STRAP_HUMAN
θ value	1.43324e-05 (rank : 63)	NC score	0.673677 (rank : 47)
Query Neighborhood Hits	414	Target Neighborhood Hits	272	Shared Neighborhood Hits	232
SwissProt Accessions	Q9Y3F4, Q9UQC8	Gene names	STRAP, MAWD, UNRIP
Domain Architecture
Description	Serine-threonine kinase receptor-associated protein (UNR-interacting protein) (WD-40 repeat protein PT-WD) (MAP activator with WD repeats).

STRN3_MOUSE
θ value	1.43324e-05 (rank : 64)	NC score	0.589131 (rank : 125)
Query Neighborhood Hits	414	Target Neighborhood Hits	309	Shared Neighborhood Hits	224
SwissProt Accessions	Q9ERG2	Gene names	Strn3, Gs2na, Sg2na
Domain Architecture
Description	Striatin-3 (Cell-cycle autoantigen SG2NA) (S/G2 antigen).

WDR1_HUMAN
θ value	1.87187e-05 (rank : 65)	NC score	0.650895 (rank : 63)
Query Neighborhood Hits	414	Target Neighborhood Hits	292	Shared Neighborhood Hits	238
SwissProt Accessions	O75083, O75313, Q8N6E5, Q9UG05, Q9UG78, Q9UQE0	Gene names	WDR1
Domain Architecture
Description	WD repeat protein 1 (Actin-interacting protein 1) (AIP1) (NORI-1).

PRP4_MOUSE
θ value	2.44474e-05 (rank : 66)	NC score	0.668870 (rank : 50)
Query Neighborhood Hits	414	Target Neighborhood Hits	308	Shared Neighborhood Hits	242
SwissProt Accessions	Q9DAW6	Gene names	Prpf4
Domain Architecture	No domain graphic available
Description	U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4).

STTP1_HUMAN
θ value	2.44474e-05 (rank : 67)	NC score	0.500816 (rank : 180)
Query Neighborhood Hits	414	Target Neighborhood Hits	232	Shared Neighborhood Hits	203
SwissProt Accessions	Q6IA86, Q53GZ0, Q687Y8, Q8N5C2, Q96GV4, Q96PI7, Q9H9N0, Q9NV81	Gene names	STATIP1
Domain Architecture	No domain graphic available
Description	Stat3-interacting protein (StIP1) (SHINC-2).

GBB1_HUMAN
θ value	3.19293e-05 (rank : 68)	NC score	0.637350 (rank : 76)
Query Neighborhood Hits	414	Target Neighborhood Hits	294	Shared Neighborhood Hits	239
SwissProt Accessions	P62873, P04697, P04901	Gene names	GNB1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta 1 (Transducin beta chain 1).

GBB1_MOUSE
θ value	3.19293e-05 (rank : 69)	NC score	0.637350 (rank : 77)
Query Neighborhood Hits	414	Target Neighborhood Hits	294	Shared Neighborhood Hits	239
SwissProt Accessions	P62874, P04697, P04901	Gene names	Gnb1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta 1 (Transducin beta chain 1).

HIRA_MOUSE
θ value	5.44631e-05 (rank : 70)	NC score	0.609443 (rank : 108)
Query Neighborhood Hits	414	Target Neighborhood Hits	274	Shared Neighborhood Hits	228
SwissProt Accessions	Q61666, O08845, Q62365	Gene names	Hira, Tuple1
Domain Architecture
Description	HIRA protein (TUP1-like enhancer of split protein 1).

STRN_HUMAN
θ value	5.44631e-05 (rank : 71)	NC score	0.585789 (rank : 129)
Query Neighborhood Hits	414	Target Neighborhood Hits	308	Shared Neighborhood Hits	233
SwissProt Accessions	O43815, Q9NP38	Gene names	STRN
Domain Architecture
Description	Striatin.

CAF1B_MOUSE
θ value	7.1131e-05 (rank : 72)	NC score	0.632843 (rank : 83)
Query Neighborhood Hits	414	Target Neighborhood Hits	385	Shared Neighborhood Hits	239
SwissProt Accessions	Q9D0N7	Gene names	Chaf1b
Domain Architecture
Description	Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-Ip60).

EMAL1_HUMAN
θ value	7.1131e-05 (rank : 73)	NC score	0.489506 (rank : 184)
Query Neighborhood Hits	414	Target Neighborhood Hits	214	Shared Neighborhood Hits	190
SwissProt Accessions	O00423	Gene names	EML1, EMAP1, EMAPL, EMAPL1
Domain Architecture
Description	Echinoderm microtubule-associated protein-like 1 (EMAP-1) (HuEMAP-1).

GBB2_HUMAN
θ value	7.1131e-05 (rank : 74)	NC score	0.641560 (rank : 73)
Query Neighborhood Hits	414	Target Neighborhood Hits	294	Shared Neighborhood Hits	245
SwissProt Accessions	P62879, P11016, P54312	Gene names	GNB2
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta 2 (Transducin beta chain 2) (G protein beta 2 subunit).

GBB2_MOUSE
θ value	7.1131e-05 (rank : 75)	NC score	0.641560 (rank : 74)
Query Neighborhood Hits	414	Target Neighborhood Hits	294	Shared Neighborhood Hits	245
SwissProt Accessions	P62880, P11016, P54312	Gene names	Gnb2
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta 2 (Transducin beta chain 2) (G protein beta 2 subunit).

UTP15_MOUSE
θ value	7.1131e-05 (rank : 76)	NC score	0.641045 (rank : 75)
Query Neighborhood Hits	414	Target Neighborhood Hits	309	Shared Neighborhood Hits	238
SwissProt Accessions	Q8C7V3, Q3TRG8, Q8K231	Gene names	Utp15
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 15 homolog (Src-associated protein SAW).

CAF1B_HUMAN
θ value	9.29e-05 (rank : 77)	NC score	0.633424 (rank : 80)
Query Neighborhood Hits	414	Target Neighborhood Hits	345	Shared Neighborhood Hits	236
SwissProt Accessions	Q13112, Q99548	Gene names	CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7
Domain Architecture
Description	Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-Ip60) (M- phase phosphoprotein 7).

PK1IP_HUMAN
θ value	9.29e-05 (rank : 78)	NC score	0.620215 (rank : 98)
Query Neighborhood Hits	414	Target Neighborhood Hits	277	Shared Neighborhood Hits	222
SwissProt Accessions	Q9NWT1, Q5T4J2, Q96QJ8, Q96T87	Gene names	PAK1IP1, PIP1, WDR84
Domain Architecture	No domain graphic available
Description	p21-activated protein kinase-interacting protein 1 (PAK1-interacting protein 1) (PAK/PLC-interacting protein 1) (hPIP1) (WD repeat protein 84).

DMXL1_MOUSE
θ value	0.000121331 (rank : 79)	NC score	0.385712 (rank : 230)
Query Neighborhood Hits	414	Target Neighborhood Hits	257	Shared Neighborhood Hits	179
SwissProt Accessions	Q6PNC0, Q3TLG8, Q6PHM6, Q8BQF2	Gene names	Dmxl1
Domain Architecture	No domain graphic available
Description	Protein DmX-like 1 (X-like 1 protein).

FBW1A_HUMAN
θ value	0.000121331 (rank : 80)	NC score	0.642529 (rank : 72)
Query Neighborhood Hits	414	Target Neighborhood Hits	329	Shared Neighborhood Hits	240
SwissProt Accessions	Q9Y297, Q9Y213	Gene names	BTRC, BTRCP, FBW1A, FBXW1A
Domain Architecture
Description	F-box/WD repeat protein 1A (F-box and WD repeats protein beta-TrCP) (E3RSIkappaB) (pIkappaBalpha-E3 receptor subunit).

FBW1B_HUMAN
θ value	0.000121331 (rank : 81)	NC score	0.645141 (rank : 68)
Query Neighborhood Hits	414	Target Neighborhood Hits	327	Shared Neighborhood Hits	240
SwissProt Accessions	Q9UKB1, Q9P2S8, Q9P2S9, Q9Y4C6	Gene names	FBXW11, BTRCP2, FBW1B, FBXW1B, KIAA0696
Domain Architecture
Description	F-box/WD repeat protein 11 (F-box/WD repeat protein 1B) (F-box and WD repeats protein beta-TrCP2).

STRN_MOUSE
θ value	0.000121331 (rank : 82)	NC score	0.588978 (rank : 126)
Query Neighborhood Hits	414	Target Neighborhood Hits	326	Shared Neighborhood Hits	240
SwissProt Accessions	O55106	Gene names	Strn
Domain Architecture
Description	Striatin.

AHI1_MOUSE
θ value	0.000158464 (rank : 83)	NC score	0.511312 (rank : 173)
Query Neighborhood Hits	414	Target Neighborhood Hits	496	Shared Neighborhood Hits	224
SwissProt Accessions	Q8K3E5, Q7TNV2, Q9CVY1	Gene names	Ahi1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein) (AHI-1).

DMXL1_HUMAN
θ value	0.000158464 (rank : 84)	NC score	0.355358 (rank : 251)
Query Neighborhood Hits	414	Target Neighborhood Hits	259	Shared Neighborhood Hits	177
SwissProt Accessions	Q9Y485	Gene names	DMXL1, XL1
Domain Architecture	No domain graphic available
Description	Protein DmX-like 1 (X-like 1 protein).

GBB4_HUMAN
θ value	0.000158464 (rank : 85)	NC score	0.633942 (rank : 79)
Query Neighborhood Hits	414	Target Neighborhood Hits	288	Shared Neighborhood Hits	241
SwissProt Accessions	Q9HAV0	Gene names	GNB4
Domain Architecture
Description	Guanine nucleotide-binding protein subunit beta 4 (Transducin beta chain 4).

STRN4_MOUSE
θ value	0.000158464 (rank : 86)	NC score	0.609672 (rank : 107)
Query Neighborhood Hits	414	Target Neighborhood Hits	324	Shared Neighborhood Hits	245
SwissProt Accessions	P58404, Q68EF5	Gene names	Strn4, Zin
Domain Architecture
Description	Striatin-4 (Zinedin).

WDR71_HUMAN
θ value	0.000158464 (rank : 87)	NC score	0.674705 (rank : 46)
Query Neighborhood Hits	414	Target Neighborhood Hits	241	Shared Neighborhood Hits	206
SwissProt Accessions	Q9BRP4, Q4G165, Q53HS9, Q7Z500, Q8TBU6, Q9HAB6	Gene names	WDR71
Domain Architecture	No domain graphic available
Description	WD repeat protein 71 (Protein G-16).

CSTF1_MOUSE
θ value	0.00020696 (rank : 88)	NC score	0.642609 (rank : 71)
Query Neighborhood Hits	414	Target Neighborhood Hits	266	Shared Neighborhood Hits	223
SwissProt Accessions	Q99LC2, Q3UMB8, Q8BJW1, Q9CSU8	Gene names	Cstf1
Domain Architecture	No domain graphic available
Description	Cleavage stimulation factor 50 kDa subunit (CSTF 50 kDa subunit) (CF-1 50 kDa subunit) (CstF-50).

GBB4_MOUSE
θ value	0.00020696 (rank : 89)	NC score	0.632898 (rank : 82)
Query Neighborhood Hits	414	Target Neighborhood Hits	283	Shared Neighborhood Hits	236
SwissProt Accessions	P29387, Q3TJJ1, Q8R475, Q9JHX8	Gene names	Gnb4
Domain Architecture
Description	Guanine nucleotide-binding protein subunit beta 4 (Transducin beta chain 4).

GBB5_HUMAN
θ value	0.00020696 (rank : 90)	NC score	0.629403 (rank : 87)
Query Neighborhood Hits	414	Target Neighborhood Hits	299	Shared Neighborhood Hits	242
SwissProt Accessions	O14775, Q9HAU9	Gene names	GNB5
Domain Architecture
Description	Guanine nucleotide-binding protein subunit beta 5 (Transducin beta chain 5) (Gbeta5).

WDR17_HUMAN
θ value	0.00020696 (rank : 91)	NC score	0.649746 (rank : 66)
Query Neighborhood Hits	414	Target Neighborhood Hits	335	Shared Neighborhood Hits	254
SwissProt Accessions	Q8IZU2	Gene names	WDR17
Domain Architecture
Description	WD repeat protein 17.

GBB5_MOUSE
θ value	0.000270298 (rank : 92)	NC score	0.629260 (rank : 89)
Query Neighborhood Hits	414	Target Neighborhood Hits	298	Shared Neighborhood Hits	242
SwissProt Accessions	P62881, O35354, P54314, Q91WB3	Gene names	Gnb5
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein subunit beta 5 (Transducin beta chain 5) (Gbeta5).

IF122_HUMAN
θ value	0.000270298 (rank : 93)	NC score	0.579813 (rank : 133)
Query Neighborhood Hits	414	Target Neighborhood Hits	244	Shared Neighborhood Hits	206
SwissProt Accessions	Q9HBG6	Gene names	IFT122, WDR10, WDR140
Domain Architecture
Description	Intraflagellar transport 122 homolog (WD repeat protein 10).

TRAF7_HUMAN
θ value	0.000270298 (rank : 94)	NC score	0.566108 (rank : 140)
Query Neighborhood Hits	414	Target Neighborhood Hits	482	Shared Neighborhood Hits	215
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

TRAF7_MOUSE
θ value	0.000270298 (rank : 95)	NC score	0.568541 (rank : 139)
Query Neighborhood Hits	414	Target Neighborhood Hits	470	Shared Neighborhood Hits	215
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

WDR19_MOUSE
θ value	0.000270298 (rank : 96)	NC score	0.199606 (rank : 299)
Query Neighborhood Hits	414	Target Neighborhood Hits	83	Shared Neighborhood Hits	56
SwissProt Accessions	Q3UGF1, Q6ZPK8, Q80VQ6, Q8C794, Q8K3R5	Gene names	Wdr19, Kiaa1638
Domain Architecture	No domain graphic available
Description	WD repeat protein 19.

WDR1_MOUSE
θ value	0.000270298 (rank : 97)	NC score	0.648543 (rank : 67)
Query Neighborhood Hits	414	Target Neighborhood Hits	296	Shared Neighborhood Hits	239
SwissProt Accessions	O88342	Gene names	Wdr1
Domain Architecture
Description	WD repeat protein 1 (Actin-interacting protein 1) (AIP1).

AAAS_HUMAN
θ value	0.00035302 (rank : 98)	NC score	0.412470 (rank : 215)
Query Neighborhood Hits	414	Target Neighborhood Hits	154	Shared Neighborhood Hits	135
SwissProt Accessions	Q9NRG9, Q9NWI6, Q9UG19	Gene names	AAAS, ADRACALA
Domain Architecture
Description	Aladin (Adracalin).

FBXW2_HUMAN
θ value	0.000461057 (rank : 99)	NC score	0.611497 (rank : 104)
Query Neighborhood Hits	414	Target Neighborhood Hits	260	Shared Neighborhood Hits	206
SwissProt Accessions	Q9UKT8, Q7Z4V6, Q8WV51, Q9HA09, Q9UKA3	Gene names	FBXW2, FBW2, FWD2
Domain Architecture
Description	F-box/WD repeat protein 2 (F-box and WD-40 domain protein 2) (MD6 protein).

GBB3_HUMAN
θ value	0.000461057 (rank : 100)	NC score	0.629625 (rank : 86)
Query Neighborhood Hits	414	Target Neighborhood Hits	282	Shared Neighborhood Hits	234
SwissProt Accessions	P16520, Q9BQC0	Gene names	GNB3
Domain Architecture
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta 3 (Transducin beta chain 3).

TBL2_HUMAN
θ value	0.000461057 (rank : 101)	NC score	0.586137 (rank : 128)
Query Neighborhood Hits	414	Target Neighborhood Hits	225	Shared Neighborhood Hits	197
SwissProt Accessions	Q9Y4P3, Q9UQE2	Gene names	TBL2, WBSCR13
Domain Architecture
Description	Transducin beta-like 2 protein (WS beta-transducin repeats protein) (WS-betaTRP) (Williams-Beuren syndrome chromosome region 13 protein).

AF9_HUMAN
θ value	0.000602161 (rank : 102)	NC score	0.070495 (rank : 349)
Query Neighborhood Hits	414	Target Neighborhood Hits	202	Shared Neighborhood Hits	18
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

DSPP_HUMAN
θ value	0.000602161 (rank : 103)	NC score	0.088294 (rank : 343)
Query Neighborhood Hits	414	Target Neighborhood Hits	645	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

GBB3_MOUSE
θ value	0.000602161 (rank : 104)	NC score	0.631366 (rank : 84)
Query Neighborhood Hits	414	Target Neighborhood Hits	283	Shared Neighborhood Hits	236
SwissProt Accessions	Q61011	Gene names	Gnb3
Domain Architecture
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta 3 (Transducin beta chain 3).

TBL3_HUMAN
θ value	0.000602161 (rank : 105)	NC score	0.670745 (rank : 49)
Query Neighborhood Hits	414	Target Neighborhood Hits	286	Shared Neighborhood Hits	233
SwissProt Accessions	Q12788	Gene names	TBL3, SAZD
Domain Architecture
Description	WD repeat protein SAZD (Transducin beta-like 3 protein).

WDR19_HUMAN
θ value	0.000602161 (rank : 106)	NC score	0.195661 (rank : 300)
Query Neighborhood Hits	414	Target Neighborhood Hits	88	Shared Neighborhood Hits	51
SwissProt Accessions	Q8NEZ3, Q8N5B4, Q9H5S0, Q9HCD4	Gene names	WDR19, KIAA1638
Domain Architecture	No domain graphic available
Description	WD repeat protein 19.

ARC1A_HUMAN
θ value	0.000786445 (rank : 107)	NC score	0.297067 (rank : 264)
Query Neighborhood Hits	414	Target Neighborhood Hits	113	Shared Neighborhood Hits	108
SwissProt Accessions	Q92747, Q7Z5U8, Q86WU5, Q8IXQ0	Gene names	ARPC1A, SOP2L
Domain Architecture
Description	Actin-related protein 2/3 complex subunit 1A (SOP2-like protein).

STRN4_HUMAN
θ value	0.000786445 (rank : 108)	NC score	0.609429 (rank : 109)
Query Neighborhood Hits	414	Target Neighborhood Hits	325	Shared Neighborhood Hits	244
SwissProt Accessions	Q9NRL3	Gene names	STRN4, ZIN
Domain Architecture
Description	Striatin-4 (Zinedin).

WDR48_HUMAN
θ value	0.000786445 (rank : 109)	NC score	0.655272 (rank : 57)
Query Neighborhood Hits	414	Target Neighborhood Hits	291	Shared Neighborhood Hits	239
SwissProt Accessions	Q8TAF3, Q63HJ2, Q658Y1, Q8N3Z1, Q9NSK8, Q9P279	Gene names	WDR48, KIAA1449
Domain Architecture	No domain graphic available
Description	WD repeat protein 48 (WD repeat endosomal protein) (p80).

NFM_MOUSE
θ value	0.00102713 (rank : 110)	NC score	0.023612 (rank : 409)
Query Neighborhood Hits	414	Target Neighborhood Hits	1159	Shared Neighborhood Hits	68
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

WDR48_MOUSE
θ value	0.00102713 (rank : 111)	NC score	0.652821 (rank : 61)
Query Neighborhood Hits	414	Target Neighborhood Hits	296	Shared Neighborhood Hits	238
SwissProt Accessions	Q8BH57, Q80TD4, Q80XI0, Q8BRM0, Q8CBK0, Q922Z9, Q9CRR1, Q9CSL0	Gene names	Wdr48, Kiaa1449
Domain Architecture	No domain graphic available
Description	WD repeat protein 48.

IFT80_MOUSE
θ value	0.00134147 (rank : 112)	NC score	0.476273 (rank : 190)
Query Neighborhood Hits	414	Target Neighborhood Hits	200	Shared Neighborhood Hits	179
SwissProt Accessions	Q8K057	Gene names	Ift80, Wdr56
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 80 homolog (WD repeat protein 56).

WDR12_HUMAN
θ value	0.00134147 (rank : 113)	NC score	0.637123 (rank : 78)
Query Neighborhood Hits	414	Target Neighborhood Hits	300	Shared Neighborhood Hits	240
SwissProt Accessions	Q9GZL7, Q96HU0, Q9NV80, Q9NYI8	Gene names	WDR12
Domain Architecture
Description	WD repeat protein 12 (YTM1 homolog).

AAAS_MOUSE
θ value	0.00175202 (rank : 114)	NC score	0.368534 (rank : 245)
Query Neighborhood Hits	414	Target Neighborhood Hits	144	Shared Neighborhood Hits	123
SwissProt Accessions	P58742, Q544M6	Gene names	Aaas
Domain Architecture
Description	Aladin (Adracalin).

BOP1_HUMAN
θ value	0.00175202 (rank : 115)	NC score	0.492809 (rank : 181)
Query Neighborhood Hits	414	Target Neighborhood Hits	257	Shared Neighborhood Hits	202
SwissProt Accessions	Q14137, Q969Z6, Q96IS8, Q9BSA7, Q9BVM0	Gene names	BOP1, KIAA0124
Domain Architecture
Description	Ribosome biogenesis protein BOP1 (Block of proliferation 1 protein).

CSTF1_HUMAN
θ value	0.00175202 (rank : 116)	NC score	0.633421 (rank : 81)
Query Neighborhood Hits	414	Target Neighborhood Hits	266	Shared Neighborhood Hits	223
SwissProt Accessions	Q05048	Gene names	CSTF1
Domain Architecture
Description	Cleavage stimulation factor 50 kDa subunit (CSTF 50 kDa subunit) (CF-1 50 kDa subunit) (CstF-50).

RPTOR_HUMAN
θ value	0.00175202 (rank : 117)	NC score	0.283658 (rank : 270)
Query Neighborhood Hits	414	Target Neighborhood Hits	121	Shared Neighborhood Hits	91
SwissProt Accessions	Q8N122, Q8N4V9, Q8TB32, Q9P2P3	Gene names	RAPTOR, KIAA1303
Domain Architecture
Description	Regulatory-associated protein of mTOR (Raptor) (P150 target of rapamycin (TOR)-scaffold protein).

SSRP1_MOUSE
θ value	0.00175202 (rank : 118)	NC score	0.104446 (rank : 334)
Query Neighborhood Hits	414	Target Neighborhood Hits	193	Shared Neighborhood Hits	32
SwissProt Accessions	Q08943, Q3U9Z2, Q3UJ75, Q4V9U4, Q8CGA6	Gene names	Ssrp1
Domain Architecture
Description	FACT complex subunit SSRP1 (Facilitates chromatin transcription complex subunit SSRP1) (Structure-specific recognition protein 1) (Recombination signal sequence recognition protein 1) (T160).

WDR24_MOUSE
θ value	0.00175202 (rank : 119)	NC score	0.524103 (rank : 161)
Query Neighborhood Hits	414	Target Neighborhood Hits	286	Shared Neighborhood Hits	209
SwissProt Accessions	Q8CFJ9	Gene names	Wdr24
Domain Architecture	No domain graphic available
Description	WD repeat protein 24.

WSB1_MOUSE
θ value	0.00175202 (rank : 120)	NC score	0.623512 (rank : 96)
Query Neighborhood Hits	414	Target Neighborhood Hits	313	Shared Neighborhood Hits	235
SwissProt Accessions	O54927	Gene names	Wsb1
Domain Architecture
Description	WD repeat and SOCS box-containing protein 1 (WSB-1).

ARC1A_MOUSE
θ value	0.00228821 (rank : 121)	NC score	0.294981 (rank : 265)
Query Neighborhood Hits	414	Target Neighborhood Hits	120	Shared Neighborhood Hits	115
SwissProt Accessions	Q9R0Q6, Q3UL75	Gene names	Arpc1a, Sid329
Domain Architecture	No domain graphic available
Description	Actin-related protein 2/3 complex subunit 1A (SOP2-like protein) (Sid 329).

CORO6_MOUSE
θ value	0.00228821 (rank : 122)	NC score	0.427514 (rank : 209)
Query Neighborhood Hits	414	Target Neighborhood Hits	246	Shared Neighborhood Hits	201
SwissProt Accessions	Q920M5, Q920M3, Q920M4	Gene names	Coro6
Domain Architecture	No domain graphic available
Description	Coronin-6 (Clipin E).

FBXW2_MOUSE
θ value	0.00228821 (rank : 123)	NC score	0.605689 (rank : 112)
Query Neighborhood Hits	414	Target Neighborhood Hits	249	Shared Neighborhood Hits	204
SwissProt Accessions	Q60584	Gene names	Fbxw2
Domain Architecture
Description	F-box/WD repeat protein 2 (F-box and WD-40 domain protein 2) (MD6 protein).

IFT80_HUMAN
θ value	0.00228821 (rank : 124)	NC score	0.466350 (rank : 194)
Query Neighborhood Hits	414	Target Neighborhood Hits	195	Shared Neighborhood Hits	175
SwissProt Accessions	Q9P2H3	Gene names	IFT80, KIAA1374, WDR56
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 80 homolog (WD repeat protein 56).

MORG1_HUMAN
θ value	0.00228821 (rank : 125)	NC score	0.654685 (rank : 58)
Query Neighborhood Hits	414	Target Neighborhood Hits	280	Shared Neighborhood Hits	229
SwissProt Accessions	Q9BRX9, Q53FT6	Gene names	MORG1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase organizer 1 (MAPK organizer 1).

U3IP2_HUMAN
θ value	0.00228821 (rank : 126)	NC score	0.624168 (rank : 95)
Query Neighborhood Hits	414	Target Neighborhood Hits	307	Shared Neighborhood Hits	227
SwissProt Accessions	O43818, Q8IZ30	Gene names	RNU3IP2, U355K
Domain Architecture
Description	U3 small nucleolar RNA-interacting protein 2 (U3 small nucleolar ribonucleoprotein-associated 55 kDa protein) (U3 snoRNP-associated 55 kDa protein) (U3-55K).

CORO7_MOUSE
θ value	0.00298849 (rank : 127)	NC score	0.504788 (rank : 177)
Query Neighborhood Hits	414	Target Neighborhood Hits	312	Shared Neighborhood Hits	239
SwissProt Accessions	Q9D2V7, Q3UDJ4, Q6P8Y8, Q8C9V7	Gene names	Coro7
Domain Architecture
Description	Coronin-7 (70 kDa WD repeat tumor rejection antigen homolog).

E41L3_MOUSE
θ value	0.00298849 (rank : 128)	NC score	0.025440 (rank : 402)
Query Neighborhood Hits	414	Target Neighborhood Hits	250	Shared Neighborhood Hits	23
SwissProt Accessions	Q9WV92, Q9R102	Gene names	Epb41l3, Dal1, Epb4.1l3
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1).

MORG1_MOUSE
θ value	0.00298849 (rank : 129)	NC score	0.656693 (rank : 55)
Query Neighborhood Hits	414	Target Neighborhood Hits	281	Shared Neighborhood Hits	227
SwissProt Accessions	Q9DAJ4, Q505C2, Q8VEB7, Q99JX9, Q9D235	Gene names	Morg1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase organizer 1 (MAPK organizer 1).

PEX7_MOUSE
θ value	0.00298849 (rank : 130)	NC score	0.616434 (rank : 101)
Query Neighborhood Hits	414	Target Neighborhood Hits	279	Shared Neighborhood Hits	226
SwissProt Accessions	P97865	Gene names	Pex7
Domain Architecture
Description	Peroxisomal targeting signal 2 receptor (PTS2 receptor) (Peroxin-7).

SSRP1_HUMAN
θ value	0.00298849 (rank : 131)	NC score	0.103505 (rank : 336)
Query Neighborhood Hits	414	Target Neighborhood Hits	187	Shared Neighborhood Hits	30
SwissProt Accessions	Q08945, Q5BJG8	Gene names	SSRP1, FACT80
Domain Architecture
Description	FACT complex subunit SSRP1 (Facilitates chromatin transcription complex subunit SSRP1) (FACT 80 kDa subunit) (FACTp80) (Chromatin- specific transcription elongation factor 80 kDa subunit) (Structure- specific recognition protein 1) (hSSRP1) (Recombination signal sequence recognition protein 1) (T160).

STB5L_HUMAN
θ value	0.00298849 (rank : 132)	NC score	0.154125 (rank : 310)
Query Neighborhood Hits	414	Target Neighborhood Hits	139	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Y2K9, Q4G1B4, Q6PIC3	Gene names	STXBP5L, KIAA1006, LLGL4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 5-like (Tomosyn-2) (Lethal(2) giant larvae protein homolog 4).

STB5L_MOUSE
θ value	0.00298849 (rank : 133)	NC score	0.154862 (rank : 309)
Query Neighborhood Hits	414	Target Neighborhood Hits	138	Shared Neighborhood Hits	94
SwissProt Accessions	Q5DQR4, Q3TSM3, Q3UVG2, Q5DQR1, Q5DQR2, Q5DQR3, Q8BS52	Gene names	Stxbp5l, Llgl4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 5-like (Tomosyn-2) (Lethal(2) giant larvae protein homolog 4).

WSB1_HUMAN
θ value	0.00298849 (rank : 134)	NC score	0.627272 (rank : 92)
Query Neighborhood Hits	414	Target Neighborhood Hits	337	Shared Neighborhood Hits	242
SwissProt Accessions	Q9Y6I7, Q9NRB1, Q9UBH9, Q9UNN6	Gene names	WSB1, SWIP1
Domain Architecture
Description	WD repeat and SOCS box-containing protein 1 (WSB-1) (SOCS box- containing WD protein SWiP-1).

CORO7_HUMAN
θ value	0.00390308 (rank : 135)	NC score	0.490586 (rank : 183)
Query Neighborhood Hits	414	Target Neighborhood Hits	315	Shared Neighborhood Hits	230
SwissProt Accessions	P57737	Gene names	CORO7
Domain Architecture
Description	Coronin-7 (70 kDa WD repeat tumor rejection antigen homolog).

DDB2_HUMAN
θ value	0.00390308 (rank : 136)	NC score	0.436468 (rank : 206)
Query Neighborhood Hits	414	Target Neighborhood Hits	175	Shared Neighborhood Hits	152
SwissProt Accessions	Q92466, Q76E54, Q76E55, Q76E56, Q76E57	Gene names	DDB2
Domain Architecture
Description	DNA damage-binding protein 2 (Damage-specific DNA-binding protein 2) (DDB p48 subunit) (DDBb) (UV-damaged DNA-binding protein 2) (UV-DDB 2).

CIR1A_HUMAN
θ value	0.00509761 (rank : 137)	NC score	0.376372 (rank : 234)
Query Neighborhood Hits	414	Target Neighborhood Hits	158	Shared Neighborhood Hits	138
SwissProt Accessions	Q969X6, Q8NCD9, Q8TF14, Q96SP0, Q96SR9, Q96SZ9, Q96T13, Q9BWK6	Gene names	CIRH1A, KIAA1988
Domain Architecture
Description	Cirhin.

MATR3_HUMAN
θ value	0.00509761 (rank : 138)	NC score	0.096487 (rank : 338)
Query Neighborhood Hits	414	Target Neighborhood Hits	325	Shared Neighborhood Hits	41
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

MATR3_MOUSE
θ value	0.00509761 (rank : 139)	NC score	0.093800 (rank : 341)
Query Neighborhood Hits	414	Target Neighborhood Hits	321	Shared Neighborhood Hits	37
SwissProt Accessions	Q8K310	Gene names	Matr3
Domain Architecture	No domain graphic available
Description	Matrin-3.

NEDD1_HUMAN
θ value	0.00509761 (rank : 140)	NC score	0.550049 (rank : 148)
Query Neighborhood Hits	414	Target Neighborhood Hits	294	Shared Neighborhood Hits	206
SwissProt Accessions	Q8NHV4, Q8NA30	Gene names	NEDD1
Domain Architecture	No domain graphic available
Description	Protein NEDD1.

NOLC1_HUMAN
θ value	0.00509761 (rank : 141)	NC score	0.061431 (rank : 354)
Query Neighborhood Hits	414	Target Neighborhood Hits	452	Shared Neighborhood Hits	35
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

WDR23_MOUSE
θ value	0.00509761 (rank : 142)	NC score	0.575397 (rank : 136)
Query Neighborhood Hits	414	Target Neighborhood Hits	271	Shared Neighborhood Hits	218
SwissProt Accessions	Q91VU6, Q3U836, Q8JZV8	Gene names	Wdr23, D14Ucla1
Domain Architecture
Description	WD repeat protein 23.

TEP1_HUMAN
θ value	0.00665767 (rank : 143)	NC score	0.603823 (rank : 114)
Query Neighborhood Hits	414	Target Neighborhood Hits	371	Shared Neighborhood Hits	245
SwissProt Accessions	Q99973	Gene names	TEP1, TLP1, TP1
Domain Architecture
Description	Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 telomerase homolog).

U3IP2_MOUSE
θ value	0.00665767 (rank : 144)	NC score	0.618762 (rank : 100)
Query Neighborhood Hits	414	Target Neighborhood Hits	312	Shared Neighborhood Hits	224
SwissProt Accessions	Q91WM3, Q8CFB7	Gene names	Rnu3ip2, U3-55k
Domain Architecture
Description	U3 small nucleolar RNA-interacting protein 2 (U3 small nucleolar ribonucleoprotein-associated 55 kDa protein) (U3 snoRNP-associated 55 kDa protein) (U3-55K).

WDR16_MOUSE
θ value	0.00665767 (rank : 145)	NC score	0.603092 (rank : 115)
Query Neighborhood Hits	414	Target Neighborhood Hits	269	Shared Neighborhood Hits	218
SwissProt Accessions	Q5F201, Q5F200, Q9D432, Q9DA68	Gene names	WDR16
Domain Architecture	No domain graphic available
Description	WD repeat protein 16.

COR1C_HUMAN
θ value	0.00869519 (rank : 146)	NC score	0.397249 (rank : 222)
Query Neighborhood Hits	414	Target Neighborhood Hits	246	Shared Neighborhood Hits	204
SwissProt Accessions	Q9ULV4, Q9NSK5	Gene names	CORO1C, CRNN4
Domain Architecture
Description	Coronin-1C (Coronin-3) (hCRNN4).

NEDD1_MOUSE
θ value	0.00869519 (rank : 147)	NC score	0.556960 (rank : 144)
Query Neighborhood Hits	414	Target Neighborhood Hits	281	Shared Neighborhood Hits	206
SwissProt Accessions	P33215, Q6NXV3, Q8BN12, Q8BN86, Q8BQL9, Q9CWK2	Gene names	Nedd1, Nedd-1
Domain Architecture	No domain graphic available
Description	Protein NEDD1 (Neural precursor cell expressed developmentally down- regulated protein 1).

PLRG1_HUMAN
θ value	0.00869519 (rank : 148)	NC score	0.650043 (rank : 65)
Query Neighborhood Hits	414	Target Neighborhood Hits	318	Shared Neighborhood Hits	242
SwissProt Accessions	O43660, Q8WUD8	Gene names	PLRG1
Domain Architecture
Description	Pleiotropic regulator 1.

BOP1_MOUSE
θ value	0.0113563 (rank : 149)	NC score	0.524002 (rank : 162)
Query Neighborhood Hits	414	Target Neighborhood Hits	267	Shared Neighborhood Hits	211
SwissProt Accessions	P97452, Q3TK87, Q91X31	Gene names	Bop1
Domain Architecture
Description	Ribosome biogenesis protein BOP1 (Block of proliferation 1 protein).

GEMI5_HUMAN
θ value	0.0113563 (rank : 150)	NC score	0.516208 (rank : 169)
Query Neighborhood Hits	414	Target Neighborhood Hits	362	Shared Neighborhood Hits	239
SwissProt Accessions	Q8TEQ6, Q8WWV4, Q969W4, Q9H9K3, Q9UFI5	Gene names	GEMIN5
Domain Architecture
Description	Gem-associated protein 5 (Gemin5).

GRWD1_HUMAN
θ value	0.0113563 (rank : 151)	NC score	0.572774 (rank : 137)
Query Neighborhood Hits	414	Target Neighborhood Hits	297	Shared Neighborhood Hits	243
SwissProt Accessions	Q9BQ67	Gene names	GRWD1, GRWD, WDR28
Domain Architecture
Description	Glutamate-rich WD repeat-containing protein 1.

RBBP5_HUMAN
θ value	0.0113563 (rank : 152)	NC score	0.546585 (rank : 155)
Query Neighborhood Hits	414	Target Neighborhood Hits	372	Shared Neighborhood Hits	191
SwissProt Accessions	Q15291	Gene names	RBBP5, RBQ3
Domain Architecture
Description	Retinoblastoma-binding protein 5 (RBBP-5) (Retinoblastoma-binding protein RBQ-3).

RPTOR_MOUSE
θ value	0.0113563 (rank : 153)	NC score	0.264829 (rank : 276)
Query Neighborhood Hits	414	Target Neighborhood Hits	129	Shared Neighborhood Hits	93
SwissProt Accessions	Q8K4Q0, Q8C9W9, Q8CBY4, Q8CDY8, Q9D4H3	Gene names	Raptor
Domain Architecture
Description	Regulatory-associated protein of mTOR (Raptor) (P150 target of rapamycin (TOR)-scaffold protein).

SEC13_HUMAN
θ value	0.0113563 (rank : 154)	NC score	0.512631 (rank : 171)
Query Neighborhood Hits	414	Target Neighborhood Hits	199	Shared Neighborhood Hits	177
SwissProt Accessions	P55735, Q9BRM6, Q9BUG7	Gene names	SEC13L1, SEC13R
Domain Architecture	No domain graphic available
Description	SEC13-related protein (SEC13-like protein 1).

UTP15_HUMAN
θ value	0.0113563 (rank : 155)	NC score	0.614849 (rank : 102)
Query Neighborhood Hits	414	Target Neighborhood Hits	296	Shared Neighborhood Hits	233
SwissProt Accessions	Q8TED0, Q6IA60, Q96E08, Q9H9F8	Gene names	UTP15
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 15 homolog.

WDR35_HUMAN
θ value	0.0113563 (rank : 156)	NC score	0.210454 (rank : 293)
Query Neighborhood Hits	414	Target Neighborhood Hits	132	Shared Neighborhood Hits	106
SwissProt Accessions	Q9P2L0, Q8NE11	Gene names	WDR35, KIAA1336
Domain Architecture
Description	WD repeat protein 35.

WSB2_MOUSE
θ value	0.0113563 (rank : 157)	NC score	0.628545 (rank : 90)
Query Neighborhood Hits	414	Target Neighborhood Hits	306	Shared Neighborhood Hits	238
SwissProt Accessions	O54929, Q9R1M8	Gene names	Wsb2, Swip2
Domain Architecture
Description	WD repeat and SOCS box-containing protein 2 (WSB-2) (SOCS box- containing WD protein SWiP-2).

COR1C_MOUSE
θ value	0.0148317 (rank : 158)	NC score	0.396968 (rank : 223)
Query Neighborhood Hits	414	Target Neighborhood Hits	251	Shared Neighborhood Hits	205
SwissProt Accessions	Q9WUM4, Q8VCQ5	Gene names	Coro1c
Domain Architecture
Description	Coronin-1C (Coronin-3).

FZR_MOUSE
θ value	0.0148317 (rank : 159)	NC score	0.599989 (rank : 116)
Query Neighborhood Hits	414	Target Neighborhood Hits	283	Shared Neighborhood Hits	235
SwissProt Accessions	Q9R1K5	Gene names	Fzr1, Fyr, Fzr
Domain Architecture
Description	Fizzy-related protein homolog (Fzr) (Cdh1/Hct1 homolog).

CALD1_HUMAN
θ value	0.0193708 (rank : 160)	NC score	0.027770 (rank : 386)
Query Neighborhood Hits	414	Target Neighborhood Hits	959	Shared Neighborhood Hits	50
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

DMXL2_HUMAN
θ value	0.0193708 (rank : 161)	NC score	0.393514 (rank : 225)
Query Neighborhood Hits	414	Target Neighborhood Hits	374	Shared Neighborhood Hits	193
SwissProt Accessions	Q8TDJ6, O94938	Gene names	DMXL2, KIAA0856
Domain Architecture	No domain graphic available
Description	Protein DmX-like 2 (Rabconnectin-3).

WDR31_HUMAN
θ value	0.0193708 (rank : 162)	NC score	0.620625 (rank : 97)
Query Neighborhood Hits	414	Target Neighborhood Hits	282	Shared Neighborhood Hits	232
SwissProt Accessions	Q8NA23, Q96EG8	Gene names	WDR31
Domain Architecture
Description	WD repeat protein 31.

WDR3_HUMAN
θ value	0.0193708 (rank : 163)	NC score	0.651000 (rank : 62)
Query Neighborhood Hits	414	Target Neighborhood Hits	334	Shared Neighborhood Hits	250
SwissProt Accessions	Q9UNX4	Gene names	WDR3
Domain Architecture
Description	WD repeat protein 3.

SEH1L_HUMAN
θ value	0.0252991 (rank : 164)	NC score	0.479491 (rank : 189)
Query Neighborhood Hits	414	Target Neighborhood Hits	145	Shared Neighborhood Hits	134
SwissProt Accessions	Q96EE3, Q8NFU6, Q96MH3, Q9C069	Gene names	SEH1L, SEC13L, SEH1
Domain Architecture
Description	Nucleoporin SEH1-like (SEC13-like protein).

WDR13_HUMAN
θ value	0.0252991 (rank : 165)	NC score	0.475347 (rank : 191)
Query Neighborhood Hits	414	Target Neighborhood Hits	186	Shared Neighborhood Hits	168
SwissProt Accessions	Q9H1Z4, Q9BUL7, Q9NWW4	Gene names	WDR13
Domain Architecture
Description	WD repeat protein 13.

WDR13_MOUSE
θ value	0.0252991 (rank : 166)	NC score	0.469459 (rank : 193)
Query Neighborhood Hits	414	Target Neighborhood Hits	195	Shared Neighborhood Hits	177
SwissProt Accessions	Q91V09	Gene names	Wdr13
Domain Architecture
Description	WD repeat protein 13.

WDR16_HUMAN
θ value	0.0252991 (rank : 167)	NC score	0.597861 (rank : 117)
Query Neighborhood Hits	414	Target Neighborhood Hits	275	Shared Neighborhood Hits	220
SwissProt Accessions	Q8N1V2, Q5DX23, Q8TC73, Q8TCI3	Gene names	WDR16, WDRPUH
Domain Architecture	No domain graphic available
Description	WD repeat protein 16 (WD40-repeat protein up-regulated in HCC).

WDR23_HUMAN
θ value	0.0252991 (rank : 168)	NC score	0.569395 (rank : 138)
Query Neighborhood Hits	414	Target Neighborhood Hits	267	Shared Neighborhood Hits	219
SwissProt Accessions	Q8TEB1, Q86U00, Q86U39, Q8NDN2, Q9H2J0, Q9H3A3, Q9H5C9	Gene names	WDR23
Domain Architecture
Description	WD repeat protein 23.

WSB2_HUMAN
θ value	0.0252991 (rank : 169)	NC score	0.630318 (rank : 85)
Query Neighborhood Hits	414	Target Neighborhood Hits	308	Shared Neighborhood Hits	240
SwissProt Accessions	Q9NYS7, Q9NRX9	Gene names	WSB2
Domain Architecture
Description	WD repeat and SOCS box-containing protein 2 (WSB-2) (CS box-containing WD protein).

CDC20_MOUSE
θ value	0.0330416 (rank : 170)	NC score	0.609744 (rank : 106)
Query Neighborhood Hits	414	Target Neighborhood Hits	325	Shared Neighborhood Hits	237
SwissProt Accessions	Q9JJ66, Q3TGP1, Q8BPG4, Q99LK3	Gene names	Cdc20
Domain Architecture
Description	Cell division cycle protein 20 homolog (p55CDC) (mmCdc20).

COPA_HUMAN
θ value	0.0330416 (rank : 171)	NC score	0.650685 (rank : 64)
Query Neighborhood Hits	414	Target Neighborhood Hits	297	Shared Neighborhood Hits	232
SwissProt Accessions	P53621	Gene names	COPA
Domain Architecture
Description	Coatomer subunit alpha (Alpha-coat protein) (Alpha-COP) (HEPCOP) (HEP- COP) [Contains: Xenin (Xenopsin-related peptide); Proxenin].

GEMI5_MOUSE
θ value	0.0330416 (rank : 172)	NC score	0.517150 (rank : 168)
Query Neighborhood Hits	414	Target Neighborhood Hits	424	Shared Neighborhood Hits	245
SwissProt Accessions	Q8BX17	Gene names	Gemin5
Domain Architecture
Description	Gem-associated protein 5 (Gemin5).

IF39_MOUSE
θ value	0.0330416 (rank : 173)	NC score	0.098873 (rank : 337)
Query Neighborhood Hits	414	Target Neighborhood Hits	206	Shared Neighborhood Hits	23
SwissProt Accessions	Q8JZQ9, Q922K2	Gene names	Eif3s9
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116).

TBL2_MOUSE
θ value	0.0330416 (rank : 174)	NC score	0.548249 (rank : 150)
Query Neighborhood Hits	414	Target Neighborhood Hits	221	Shared Neighborhood Hits	194
SwissProt Accessions	Q9R099	Gene names	Tbl2
Domain Architecture
Description	Transducin beta-like 2 protein.

TEP1_MOUSE
θ value	0.0330416 (rank : 175)	NC score	0.589238 (rank : 124)
Query Neighborhood Hits	414	Target Neighborhood Hits	344	Shared Neighborhood Hits	246
SwissProt Accessions	P97499	Gene names	Tep1, Tp1
Domain Architecture
Description	Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 homolog).

WDR22_HUMAN
θ value	0.0330416 (rank : 176)	NC score	0.518940 (rank : 166)
Query Neighborhood Hits	414	Target Neighborhood Hits	328	Shared Neighborhood Hits	212
SwissProt Accessions	Q96JK2, O60559, Q8N3V3, Q8N3V5	Gene names	WDR22, BCRG2, KIAA1824
Domain Architecture
Description	WD repeat protein 22 (Breakpoint cluster region protein 2) (BCRP2).

WDR22_MOUSE
θ value	0.0330416 (rank : 177)	NC score	0.520555 (rank : 164)
Query Neighborhood Hits	414	Target Neighborhood Hits	302	Shared Neighborhood Hits	206
SwissProt Accessions	Q80T85, Q80VT3, Q80ZW6, Q8BIP8, Q8BVK5, Q8K0Q6	Gene names	Wdr22, Kiaa1824
Domain Architecture
Description	WD repeat protein 22.

WDR26_MOUSE
θ value	0.0330416 (rank : 178)	NC score	0.627227 (rank : 93)
Query Neighborhood Hits	414	Target Neighborhood Hits	295	Shared Neighborhood Hits	245
SwissProt Accessions	Q8C6G8, Q8C4F3, Q8VDZ6	Gene names	Wdr26
Domain Architecture
Description	WD repeat protein 26.

WDR36_HUMAN
θ value	0.0330416 (rank : 179)	NC score	0.597134 (rank : 119)
Query Neighborhood Hits	414	Target Neighborhood Hits	274	Shared Neighborhood Hits	226
SwissProt Accessions	Q8NI36, Q8N1Q2	Gene names	WDR36
Domain Architecture
Description	WD repeat protein 36 (T-cell activation WD repeat-containing protein) (TA-WDRP).

WDR53_MOUSE
θ value	0.0330416 (rank : 180)	NC score	0.554291 (rank : 145)
Query Neighborhood Hits	414	Target Neighborhood Hits	254	Shared Neighborhood Hits	213
SwissProt Accessions	Q9DB94	Gene names	Wdr53
Domain Architecture	No domain graphic available
Description	WD repeat protein 53.

WIPI2_HUMAN
θ value	0.0330416 (rank : 181)	NC score	0.117026 (rank : 330)
Query Neighborhood Hits	414	Target Neighborhood Hits	56	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y4P8, Q5MNZ8, Q6FI96, Q75L50, Q96IE4, Q9Y364	Gene names	WIPI2
Domain Architecture	No domain graphic available
Description	WD repeat domain phosphoinositide-interacting protein 2 (WIPI-2) (WIPI49-like protein 2).

COR2A_HUMAN
θ value	0.0431538 (rank : 182)	NC score	0.381355 (rank : 232)
Query Neighborhood Hits	414	Target Neighborhood Hits	214	Shared Neighborhood Hits	183
SwissProt Accessions	Q92828, Q92829, Q9BWS5	Gene names	CORO2A, IR10, WDR2
Domain Architecture
Description	Coronin-2A (WD repeat-containing protein 2) (IR10).

IF39_HUMAN
θ value	0.0431538 (rank : 183)	NC score	0.096248 (rank : 339)
Query Neighborhood Hits	414	Target Neighborhood Hits	187	Shared Neighborhood Hits	23
SwissProt Accessions	P55884, Q9UMF9	Gene names	EIF3S9
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116) (eIF3 p110) (eIF3b) (Prt1 homolog) (hPrt1).

WDR12_MOUSE
θ value	0.0431538 (rank : 184)	NC score	0.629397 (rank : 88)
Query Neighborhood Hits	414	Target Neighborhood Hits	301	Shared Neighborhood Hits	244
SwissProt Accessions	Q9JJA4, Q9CST3, Q9JKF5	Gene names	Wdr12
Domain Architecture
Description	WD repeat protein 12 (YTM1 homolog).

WDR26_HUMAN
θ value	0.0431538 (rank : 185)	NC score	0.627374 (rank : 91)
Query Neighborhood Hits	414	Target Neighborhood Hits	294	Shared Neighborhood Hits	245
SwissProt Accessions	Q9H7D7, Q86UY4	Gene names	WDR26
Domain Architecture
Description	WD repeat protein 26.

DDB2_MOUSE
θ value	0.0563607 (rank : 186)	NC score	0.401810 (rank : 217)
Query Neighborhood Hits	414	Target Neighborhood Hits	175	Shared Neighborhood Hits	156
SwissProt Accessions	Q99J79	Gene names	Ddb2
Domain Architecture	No domain graphic available
Description	DNA damage-binding protein 2 (Damage-specific DNA-binding protein 2).

FANCM_HUMAN
θ value	0.0563607 (rank : 187)	NC score	0.036317 (rank : 370)
Query Neighborhood Hits	414	Target Neighborhood Hits	210	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

MEP50_MOUSE
θ value	0.0563607 (rank : 188)	NC score	0.552933 (rank : 146)
Query Neighborhood Hits	414	Target Neighborhood Hits	271	Shared Neighborhood Hits	215
SwissProt Accessions	Q99J09, Q3TFJ1, Q8BSH8, Q9CZY5	Gene names	Wdr77, Mep50
Domain Architecture
Description	Methylosome protein 50 (MEP50 protein) (WD repeat protein 77).

SAFB2_MOUSE
θ value	0.0563607 (rank : 189)	NC score	0.027955 (rank : 385)
Query Neighborhood Hits	414	Target Neighborhood Hits	581	Shared Neighborhood Hits	27
SwissProt Accessions	Q80YR5, Q8K153	Gene names	Safb2
Domain Architecture
Description	Scaffold attachment factor B2.

SEC13_MOUSE
θ value	0.0563607 (rank : 190)	NC score	0.516039 (rank : 170)
Query Neighborhood Hits	414	Target Neighborhood Hits	195	Shared Neighborhood Hits	179
SwissProt Accessions	Q9D1M0, Q99M12, Q9D712	Gene names	Sec13l1
Domain Architecture	No domain graphic available
Description	SEC13-related protein (SEC13-like protein 1).

WDR35_MOUSE
θ value	0.0563607 (rank : 191)	NC score	0.189068 (rank : 302)
Query Neighborhood Hits	414	Target Neighborhood Hits	126	Shared Neighborhood Hits	100
SwissProt Accessions	Q8BND3, Q8CDL4	Gene names	Wdr35
Domain Architecture
Description	WD repeat protein 35.

BBX_MOUSE
θ value	0.0736092 (rank : 192)	NC score	0.043845 (rank : 366)
Query Neighborhood Hits	414	Target Neighborhood Hits	152	Shared Neighborhood Hits	26
SwissProt Accessions	Q8VBW5, Q3TZK1, Q6NXY8, Q6PEU3, Q8BQJ7, Q8C7E0, Q8CDQ0, Q8CDV1, Q8VI48, Q8VI49, Q8VI50, Q9CS94	Gene names	Bbx, Hbp2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

COR2A_MOUSE
θ value	0.0736092 (rank : 193)	NC score	0.366967 (rank : 246)
Query Neighborhood Hits	414	Target Neighborhood Hits	204	Shared Neighborhood Hits	174
SwissProt Accessions	Q8C0P5, Q3U6H8, Q8BW42	Gene names	Coro2a
Domain Architecture	No domain graphic available
Description	Coronin-2A.

DSPP_MOUSE
θ value	0.0736092 (rank : 194)	NC score	0.070812 (rank : 348)
Query Neighborhood Hits	414	Target Neighborhood Hits	491	Shared Neighborhood Hits	44
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

LEO1_MOUSE
θ value	0.0736092 (rank : 195)	NC score	0.063701 (rank : 351)
Query Neighborhood Hits	414	Target Neighborhood Hits	946	Shared Neighborhood Hits	73
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

NUP37_HUMAN
θ value	0.0736092 (rank : 196)	NC score	0.412612 (rank : 214)
Query Neighborhood Hits	414	Target Neighborhood Hits	153	Shared Neighborhood Hits	140
SwissProt Accessions	Q8NFH4, Q9H644	Gene names	NUP37
Domain Architecture
Description	Nucleoporin Nup37 (p37).

PLRG1_MOUSE
θ value	0.0736092 (rank : 197)	NC score	0.643406 (rank : 69)
Query Neighborhood Hits	414	Target Neighborhood Hits	308	Shared Neighborhood Hits	242
SwissProt Accessions	Q922V4, O55039	Gene names	Plrg1
Domain Architecture
Description	Pleiotropic regulator 1.

WDR18_MOUSE
θ value	0.0736092 (rank : 198)	NC score	0.549467 (rank : 149)
Query Neighborhood Hits	414	Target Neighborhood Hits	239	Shared Neighborhood Hits	198
SwissProt Accessions	Q4VBE8	Gene names	Wdr18
Domain Architecture	No domain graphic available
Description	WD repeat protein 18.

CDC20_HUMAN
θ value	0.0961366 (rank : 199)	NC score	0.607596 (rank : 111)
Query Neighborhood Hits	414	Target Neighborhood Hits	329	Shared Neighborhood Hits	233
SwissProt Accessions	Q12834, Q9BW56, Q9UQI9	Gene names	CDC20
Domain Architecture
Description	Cell division cycle protein 20 homolog (p55CDC).

FZR_HUMAN
θ value	0.0961366 (rank : 200)	NC score	0.596806 (rank : 120)
Query Neighborhood Hits	414	Target Neighborhood Hits	279	Shared Neighborhood Hits	232
SwissProt Accessions	Q9UM11, O75869, Q86U66, Q96NW8, Q9UI96, Q9ULH8, Q9UM10, Q9UNQ1, Q9Y2T8	Gene names	FZR1, CDH1, FYR, FZR, KIAA1242
Domain Architecture
Description	Fizzy-related protein homolog (Fzr) (Cdh1/Hct1 homolog) (hCDH1) (CDC20-like protein 1).

GRWD1_MOUSE
θ value	0.0961366 (rank : 201)	NC score	0.563232 (rank : 142)
Query Neighborhood Hits	414	Target Neighborhood Hits	296	Shared Neighborhood Hits	240
SwissProt Accessions	Q810D6, Q922H3	Gene names	Grwd1, A301
Domain Architecture	No domain graphic available
Description	Glutamate-rich WD repeat-containing protein 1 (Protein A301).

PEX7_HUMAN
θ value	0.0961366 (rank : 202)	NC score	0.613097 (rank : 103)
Query Neighborhood Hits	414	Target Neighborhood Hits	275	Shared Neighborhood Hits	226
SwissProt Accessions	O00628	Gene names	PEX7, PTS2R
Domain Architecture
Description	Peroxisomal targeting signal 2 receptor (PTS2 receptor) (Peroxin-7).

PRP4B_MOUSE
θ value	0.0961366 (rank : 203)	NC score	0.002519 (rank : 483)
Query Neighborhood Hits	414	Target Neighborhood Hits	1040	Shared Neighborhood Hits	24
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

AAMP_HUMAN
θ value	0.125558 (rank : 204)	NC score	0.626409 (rank : 94)
Query Neighborhood Hits	414	Target Neighborhood Hits	294	Shared Neighborhood Hits	231
SwissProt Accessions	Q13685, Q8WUJ9, Q96H92	Gene names	AAMP
Domain Architecture
Description	Angio-associated migratory cell protein.

CD2L7_HUMAN
θ value	0.125558 (rank : 205)	NC score	-0.003892 (rank : 491)
Query Neighborhood Hits	414	Target Neighborhood Hits	1275	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

COR1B_MOUSE
θ value	0.125558 (rank : 206)	NC score	0.373673 (rank : 238)
Query Neighborhood Hits	414	Target Neighborhood Hits	235	Shared Neighborhood Hits	191
SwissProt Accessions	Q9WUM3, Q3UEB1, Q9CVA2	Gene names	Coro1b
Domain Architecture
Description	Coronin-1B (Coronin-2).

DC1I2_HUMAN
θ value	0.125558 (rank : 207)	NC score	0.218839 (rank : 290)
Query Neighborhood Hits	414	Target Neighborhood Hits	201	Shared Neighborhood Hits	129
SwissProt Accessions	Q13409, Q96NG7, Q96S87, Q9BXZ5, Q9NT58	Gene names	DYNC1I2, DNCI2, DNCIC2
Domain Architecture
Description	Cytoplasmic dynein 1 intermediate chain 2 (Dynein intermediate chain 2, cytosolic) (DH IC-2) (Cytoplasmic dynein intermediate chain 2).

DDX46_HUMAN
θ value	0.125558 (rank : 208)	NC score	0.017803 (rank : 428)
Query Neighborhood Hits	414	Target Neighborhood Hits	357	Shared Neighborhood Hits	22
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

LYST_MOUSE
θ value	0.125558 (rank : 209)	NC score	0.269611 (rank : 275)
Query Neighborhood Hits	414	Target Neighborhood Hits	286	Shared Neighborhood Hits	149
SwissProt Accessions	P97412, Q62403, Q8VBS6	Gene names	Lyst, Bg, Chs1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige protein) (CHS1 homolog).

MEP50_HUMAN
θ value	0.125558 (rank : 210)	NC score	0.548099 (rank : 151)
Query Neighborhood Hits	414	Target Neighborhood Hits	268	Shared Neighborhood Hits	212
SwissProt Accessions	Q9BQA1, Q96GK4, Q9BWY3	Gene names	WDR77, MEP50
Domain Architecture
Description	Methylosome protein 50 (MEP50 protein) (WD repeat protein 77).

PLAP_HUMAN
θ value	0.125558 (rank : 211)	NC score	0.585014 (rank : 131)
Query Neighborhood Hits	414	Target Neighborhood Hits	266	Shared Neighborhood Hits	209
SwissProt Accessions	Q9Y263, Q53EU5, Q5VY33, Q9NUL8, Q9NVE9, Q9UF53, Q9Y5L1	Gene names	PLAA, PLAP
Domain Architecture
Description	Phospholipase A-2-activating protein (PLAP) (PLA2P).

PLAP_MOUSE
θ value	0.125558 (rank : 212)	NC score	0.582325 (rank : 132)
Query Neighborhood Hits	414	Target Neighborhood Hits	261	Shared Neighborhood Hits	209
SwissProt Accessions	P27612, Q8C6C4	Gene names	Plaa, Plap
Domain Architecture
Description	Phospholipase A-2-activating protein (PLAP).

PSIP1_HUMAN
θ value	0.125558 (rank : 213)	NC score	0.049423 (rank : 362)
Query Neighborhood Hits	414	Target Neighborhood Hits	341	Shared Neighborhood Hits	32
SwissProt Accessions	O75475, O00256, O95368, Q6P391, Q86YB9, Q9NZI3, Q9UER6	Gene names	PSIP1, DFS70, LEDGF, PSIP2
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (Transcriptional coactivator p75/p52) (Dense fine speckles 70 kDa protein) (DFS 70) (CLL-associated antigen KW-7).

WDR31_MOUSE
θ value	0.125558 (rank : 214)	NC score	0.620096 (rank : 99)
Query Neighborhood Hits	414	Target Neighborhood Hits	287	Shared Neighborhood Hits	229
SwissProt Accessions	Q9JHB4, Q3URZ0, Q9D3N4	Gene names	Wdr31
Domain Architecture
Description	WD repeat protein 31 (Spermatid WD repeat protein) (spWD).

WDR34_MOUSE
θ value	0.125558 (rank : 215)	NC score	0.178154 (rank : 303)
Query Neighborhood Hits	414	Target Neighborhood Hits	105	Shared Neighborhood Hits	83
SwissProt Accessions	Q5U4F6	Gene names	Wdr34
Domain Architecture	No domain graphic available
Description	WD repeat protein 34.

WDR53_HUMAN
θ value	0.125558 (rank : 216)	NC score	0.551316 (rank : 147)
Query Neighborhood Hits	414	Target Neighborhood Hits	251	Shared Neighborhood Hits	217
SwissProt Accessions	Q7Z5U6	Gene names	WDR53
Domain Architecture	No domain graphic available
Description	WD repeat protein 53.

WDR55_MOUSE
θ value	0.125558 (rank : 217)	NC score	0.558526 (rank : 143)
Query Neighborhood Hits	414	Target Neighborhood Hits	236	Shared Neighborhood Hits	197
SwissProt Accessions	Q9CX97	Gene names	Wdr55
Domain Architecture	No domain graphic available
Description	WD repeat protein 55.

WIPI2_MOUSE
θ value	0.125558 (rank : 218)	NC score	0.108500 (rank : 331)
Query Neighborhood Hits	414	Target Neighborhood Hits	55	Shared Neighborhood Hits	38
SwissProt Accessions	Q80W47	Gene names	Wipi2
Domain Architecture	No domain graphic available
Description	WD repeat domain phosphoinositide-interacting protein 2 (WIPI-2).

ARI1A_HUMAN
θ value	0.163984 (rank : 219)	NC score	0.025138 (rank : 404)
Query Neighborhood Hits	414	Target Neighborhood Hits	787	Shared Neighborhood Hits	24
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

BAZ2B_HUMAN
θ value	0.163984 (rank : 220)	NC score	0.036280 (rank : 371)
Query Neighborhood Hits	414	Target Neighborhood Hits	803	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

HMGB3_MOUSE
θ value	0.163984 (rank : 221)	NC score	0.059807 (rank : 356)
Query Neighborhood Hits	414	Target Neighborhood Hits	88	Shared Neighborhood Hits	22
SwissProt Accessions	O54879	Gene names	Hmgb3, Hmg2a, Hmg4
Domain Architecture
Description	High mobility group protein B3 (High mobility group protein 4) (HMG-4) (High mobility group protein 2a) (HMG-2a).

MS3L1_MOUSE
θ value	0.163984 (rank : 222)	NC score	0.035173 (rank : 372)
Query Neighborhood Hits	414	Target Neighborhood Hits	67	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WVG9	Gene names	Msl3l1, Msl31
Domain Architecture
Description	Male-specific lethal 3-like 1 (MSL3-like 1) (Male-specific lethal-3 homolog 1).

NUP37_MOUSE
θ value	0.163984 (rank : 223)	NC score	0.430040 (rank : 208)
Query Neighborhood Hits	414	Target Neighborhood Hits	159	Shared Neighborhood Hits	149
SwissProt Accessions	Q9CWU9	Gene names	Nup37
Domain Architecture
Description	Nucleoporin Nup37.

TF3C2_HUMAN
θ value	0.163984 (rank : 224)	NC score	0.131921 (rank : 326)
Query Neighborhood Hits	414	Target Neighborhood Hits	168	Shared Neighborhood Hits	78
SwissProt Accessions	Q8WUA4, Q16632, Q9BWI7	Gene names	GTF3C2, KIAA0011
Domain Architecture
Description	General transcription factor 3C polypeptide 2 (Transcription factor IIIC-subunit beta) (TF3C-beta) (TFIIIC 110 kDa subunit) (TFIIIC110).

TR95_MOUSE
θ value	0.163984 (rank : 225)	NC score	0.155363 (rank : 308)
Query Neighborhood Hits	414	Target Neighborhood Hits	95	Shared Neighborhood Hits	76
SwissProt Accessions	Q6PGF3	Gene names	Thrap5
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein complex 95 kDa component (Trap95) (Thyroid hormone receptor-associated protein 5) (Vitamin D3 receptor-interacting protein complex component DRIP92).

WDR75_HUMAN
θ value	0.163984 (rank : 226)	NC score	0.449463 (rank : 203)
Query Neighborhood Hits	414	Target Neighborhood Hits	193	Shared Neighborhood Hits	153
SwissProt Accessions	Q8IWA0, Q96J10, Q9H8U8, Q9H9U5, Q9H9V8, Q9UIX2	Gene names	WDR75
Domain Architecture	No domain graphic available
Description	WD repeat protein 75.

COR1A_HUMAN
θ value	0.21417 (rank : 227)	NC score	0.392933 (rank : 227)
Query Neighborhood Hits	414	Target Neighborhood Hits	240	Shared Neighborhood Hits	196
SwissProt Accessions	P31146	Gene names	CORO1A, CORO1
Domain Architecture
Description	Coronin-1A (Coronin-like protein p57) (Coronin-like protein A) (CLIPINA) (Tryptophan aspartate-containing coat protein) (TACO).

DDX46_MOUSE
θ value	0.21417 (rank : 228)	NC score	0.017201 (rank : 432)
Query Neighborhood Hits	414	Target Neighborhood Hits	358	Shared Neighborhood Hits	23
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

LZTS1_MOUSE
θ value	0.21417 (rank : 229)	NC score	0.023098 (rank : 412)
Query Neighborhood Hits	414	Target Neighborhood Hits	540	Shared Neighborhood Hits	29
SwissProt Accessions	P60853	Gene names	Lzts1, Fez1
Domain Architecture	No domain graphic available
Description	Leucine zipper putative tumor suppressor 1 (F37/Esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

DC1I2_MOUSE
θ value	0.279714 (rank : 230)	NC score	0.222174 (rank : 289)
Query Neighborhood Hits	414	Target Neighborhood Hits	209	Shared Neighborhood Hits	131
SwissProt Accessions	O88487, Q3TGH7	Gene names	Dync1i2, Dnci2, Dncic2
Domain Architecture
Description	Cytoplasmic dynein 1 intermediate chain 2 (Dynein intermediate chain 2, cytosolic) (DH IC-2) (Cytoplasmic dynein intermediate chain 2).

DMP1_MOUSE
θ value	0.279714 (rank : 231)	NC score	0.063038 (rank : 352)
Query Neighborhood Hits	414	Target Neighborhood Hits	498	Shared Neighborhood Hits	51
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

EMAL4_HUMAN
θ value	0.279714 (rank : 232)	NC score	0.473248 (rank : 192)
Query Neighborhood Hits	414	Target Neighborhood Hits	306	Shared Neighborhood Hits	201
SwissProt Accessions	Q9HC35	Gene names	EML4, C2orf2, EMAPL4
Domain Architecture
Description	Echinoderm microtubule-associated protein-like 4 (EMAP-4) (Restrictedly overexpressed proliferation-associated protein) (Ropp 120).

LIMA1_HUMAN
θ value	0.279714 (rank : 233)	NC score	0.028786 (rank : 383)
Query Neighborhood Hits	414	Target Neighborhood Hits	309	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UHB6, Q2TAN7, Q9BVF2, Q9H8J1, Q9HBN5, Q9NX96, Q9NXC3, Q9NXU6, Q9P0H8, Q9UHB5	Gene names	LIMA1, EPLIN, SREBP3
Domain Architecture
Description	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm).

MAP1B_MOUSE
θ value	0.279714 (rank : 234)	NC score	0.037884 (rank : 369)
Query Neighborhood Hits	414	Target Neighborhood Hits	977	Shared Neighborhood Hits	67
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

TLK1_MOUSE
θ value	0.279714 (rank : 235)	NC score	0.000622 (rank : 487)
Query Neighborhood Hits	414	Target Neighborhood Hits	947	Shared Neighborhood Hits	21
SwissProt Accessions	Q8C0V0	Gene names	Tlk1
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1) (Tousled- like kinase 1).

WDFY2_HUMAN
θ value	0.279714 (rank : 236)	NC score	0.456720 (rank : 200)
Query Neighborhood Hits	414	Target Neighborhood Hits	332	Shared Neighborhood Hits	230
SwissProt Accessions	Q96P53, Q96CS1	Gene names	WDFY2, WDF2, ZFYVE22
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2) (Zinc finger FYVE domain-containing protein 22).

DDX21_HUMAN
θ value	0.365318 (rank : 237)	NC score	0.016942 (rank : 433)
Query Neighborhood Hits	414	Target Neighborhood Hits	308	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DMP1_HUMAN
θ value	0.365318 (rank : 238)	NC score	0.064190 (rank : 350)
Query Neighborhood Hits	414	Target Neighborhood Hits	491	Shared Neighborhood Hits	49
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

ERCC8_MOUSE
θ value	0.365318 (rank : 239)	NC score	0.577874 (rank : 135)
Query Neighborhood Hits	414	Target Neighborhood Hits	269	Shared Neighborhood Hits	226
SwissProt Accessions	Q8CFD5, Q3U066, Q8VDC4, Q9CWK7	Gene names	Ercc8, Ckn1, Csa
Domain Architecture	No domain graphic available
Description	DNA excision repair protein ERCC-8 (Cockayne syndrome WD repeat protein CSA homolog).

LYST_HUMAN
θ value	0.365318 (rank : 240)	NC score	0.290855 (rank : 266)
Query Neighborhood Hits	414	Target Neighborhood Hits	324	Shared Neighborhood Hits	161
SwissProt Accessions	Q99698, O43274, Q5T2U9, Q96TD7, Q96TD8, Q99709, Q9H133	Gene names	LYST, CHS, CHS1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige homolog).

MORC2_HUMAN
θ value	0.365318 (rank : 241)	NC score	0.020552 (rank : 421)
Query Neighborhood Hits	414	Target Neighborhood Hits	207	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y6X9, Q9UF28, Q9Y6V2	Gene names	MORC2, KIAA0852, ZCWCC1
Domain Architecture
Description	MORC family CW-type zinc finger protein 2 (Zinc finger CW-type coiled- coil domain protein 1).

NOL8_HUMAN
θ value	0.365318 (rank : 242)	NC score	0.044591 (rank : 365)
Query Neighborhood Hits	414	Target Neighborhood Hits	297	Shared Neighborhood Hits	34
SwissProt Accessions	Q76FK4, Q5TCC7, Q5TCC8, Q5TCD3, Q5TCD5, Q5TCD6, Q5TCD7, Q76D35, Q7L3E2, Q9H586, Q9H795, Q9H7W7, Q9H9J6, Q9NWA4, Q9NWM4	Gene names	NOL8, NOP132
Domain Architecture	No domain graphic available
Description	Nucleolar protein 8 (Nucleolar protein Nop132).

PCLO_MOUSE
θ value	0.365318 (rank : 243)	NC score	0.014382 (rank : 446)
Query Neighborhood Hits	414	Target Neighborhood Hits	2275	Shared Neighborhood Hits	88
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

STTP1_MOUSE
θ value	0.365318 (rank : 244)	NC score	0.487297 (rank : 185)
Query Neighborhood Hits	414	Target Neighborhood Hits	246	Shared Neighborhood Hits	212
SwissProt Accessions	Q91WG4, Q3TIH5, Q3TIT0, Q8CBW6, Q9ESY7	Gene names	Statip1
Domain Architecture	No domain graphic available
Description	Stat3-interacting protein (StIP1).

TCF20_MOUSE
θ value	0.365318 (rank : 245)	NC score	0.031958 (rank : 376)
Query Neighborhood Hits	414	Target Neighborhood Hits	396	Shared Neighborhood Hits	31
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

TR95_HUMAN
θ value	0.365318 (rank : 246)	NC score	0.103782 (rank : 335)
Query Neighborhood Hits	414	Target Neighborhood Hits	50	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y2X0, Q6PJT2, Q96AD4, Q96I35, Q9Y652	Gene names	THRAP5, DRIP92
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein complex 95 kDa component (Trap95) (Thyroid hormone receptor-associated protein 5) (Vitamin D3 receptor-interacting protein complex component DRIP92).

WDR47_HUMAN
θ value	0.365318 (rank : 247)	NC score	0.585278 (rank : 130)
Query Neighborhood Hits	414	Target Neighborhood Hits	295	Shared Neighborhood Hits	221
SwissProt Accessions	O94967, Q8IXT7, Q8IYU9	Gene names	WDR47, KIAA0893
Domain Architecture	No domain graphic available
Description	WD repeat protein 47.

WDR47_MOUSE
θ value	0.365318 (rank : 248)	NC score	0.586536 (rank : 127)
Query Neighborhood Hits	414	Target Neighborhood Hits	295	Shared Neighborhood Hits	222
SwissProt Accessions	Q8CGF6, Q80TP4	Gene names	Wdr47, Kiaa0893
Domain Architecture	No domain graphic available
Description	WD repeat protein 47.

EDD1_MOUSE
θ value	0.47712 (rank : 249)	NC score	0.026394 (rank : 394)
Query Neighborhood Hits	414	Target Neighborhood Hits	167	Shared Neighborhood Hits	11
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

HMGB3_HUMAN
θ value	0.47712 (rank : 250)	NC score	0.056272 (rank : 357)
Query Neighborhood Hits	414	Target Neighborhood Hits	86	Shared Neighborhood Hits	21
SwissProt Accessions	O15347, O95556, Q6NS40	Gene names	HMGB3, HMG2A, HMG4
Domain Architecture
Description	High mobility group protein B3 (High mobility group protein 4) (HMG-4) (High mobility group protein 2a) (HMG-2a).

LEO1_HUMAN
θ value	0.47712 (rank : 251)	NC score	0.061448 (rank : 353)
Query Neighborhood Hits	414	Target Neighborhood Hits	958	Shared Neighborhood Hits	72
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

RAE1L_HUMAN
θ value	0.47712 (rank : 252)	NC score	0.521638 (rank : 163)
Query Neighborhood Hits	414	Target Neighborhood Hits	222	Shared Neighborhood Hits	194
SwissProt Accessions	P78406, O15306, Q3SYL7, Q5TCH8, Q6V708, Q9H100, Q9NQM6	Gene names	RAE1, MRNP41
Domain Architecture
Description	mRNA-associated protein mrnp 41 (Rae1 protein homolog).

RBBP4_HUMAN
θ value	0.47712 (rank : 253)	NC score	0.510816 (rank : 175)
Query Neighborhood Hits	414	Target Neighborhood Hits	291	Shared Neighborhood Hits	233
SwissProt Accessions	Q09028, P31149, Q53H02, Q96BV9	Gene names	RBBP4, RBAP48
Domain Architecture
Description	Histone-binding protein RBBP4 (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48) (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome remodeling factor subunit RBAP48).

RBBP4_MOUSE
θ value	0.47712 (rank : 254)	NC score	0.511890 (rank : 172)
Query Neighborhood Hits	414	Target Neighborhood Hits	289	Shared Neighborhood Hits	231
SwissProt Accessions	Q60972	Gene names	Rbbp4, Rbap48
Domain Architecture
Description	Histone-binding protein RBBP4 (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48) (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome remodeling factor subunit RBAP48).

SOX15_HUMAN
θ value	0.47712 (rank : 255)	NC score	0.034659 (rank : 373)
Query Neighborhood Hits	414	Target Neighborhood Hits	134	Shared Neighborhood Hits	20
SwissProt Accessions	O60248, P35717, Q9Y6W7	Gene names	SOX15, SOX12, SOX20, SOX26, SOX27
Domain Architecture
Description	SOX-15 protein (SOX-20 protein) (SOX-12 protein).

SRRM2_HUMAN
θ value	0.47712 (rank : 256)	NC score	0.028676 (rank : 384)
Query Neighborhood Hits	414	Target Neighborhood Hits	1296	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

WDR7_MOUSE
θ value	0.47712 (rank : 257)	NC score	0.376598 (rank : 233)
Query Neighborhood Hits	414	Target Neighborhood Hits	226	Shared Neighborhood Hits	176
SwissProt Accessions	Q920I9, Q80TY3, Q920J0	Gene names	Wdr7, Kiaa0541, Trag
Domain Architecture	No domain graphic available
Description	WD repeat protein 7 (TGF-beta resistance-associated protein TRAG).

AP3B1_MOUSE
θ value	0.62314 (rank : 258)	NC score	0.022295 (rank : 415)
Query Neighborhood Hits	414	Target Neighborhood Hits	302	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z1T1, Q91YR4	Gene names	Ap3b1
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

ERCC8_HUMAN
θ value	0.62314 (rank : 259)	NC score	0.578941 (rank : 134)
Query Neighborhood Hits	414	Target Neighborhood Hits	267	Shared Neighborhood Hits	226
SwissProt Accessions	Q13216, Q6FHX5, Q96GB9	Gene names	ERCC8, CKN1, CSA
Domain Architecture
Description	DNA excision repair protein ERCC-8 (Cockayne syndrome WD repeat protein CSA).

FBXW5_MOUSE
θ value	0.62314 (rank : 260)	NC score	0.317203 (rank : 257)
Query Neighborhood Hits	414	Target Neighborhood Hits	159	Shared Neighborhood Hits	127
SwissProt Accessions	Q9QXW2	Gene names	Fbxw5, Fbw5
Domain Architecture
Description	F-box/WD repeat protein 5 (F-box and WD-40 domain protein 5).

HPS5_MOUSE
θ value	0.62314 (rank : 261)	NC score	0.051708 (rank : 358)
Query Neighborhood Hits	414	Target Neighborhood Hits	69	Shared Neighborhood Hits	18
SwissProt Accessions	P59438	Gene names	Hps5, Ru2
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 5 protein homolog (Ruby-eye protein 2) (Ru2).

KI21B_HUMAN
θ value	0.62314 (rank : 262)	NC score	0.260940 (rank : 277)
Query Neighborhood Hits	414	Target Neighborhood Hits	1017	Shared Neighborhood Hits	241
SwissProt Accessions	O75037, Q5T4J3	Gene names	KIF21B, KIAA0449
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B.

LYRIC_HUMAN
θ value	0.62314 (rank : 263)	NC score	0.046864 (rank : 363)
Query Neighborhood Hits	414	Target Neighborhood Hits	99	Shared Neighborhood Hits	20
SwissProt Accessions	Q86UE4, Q6PK07, Q8TCX3	Gene names	MTDH, AEG1, LYRIC
Domain Architecture	No domain graphic available
Description	Protein LYRIC (Lysine-rich CEACAM1 co-isolated protein) (3D3/lyric) (Metastasis adhesion protein) (Metadherin) (Astrocyte elevated gene-1 protein) (AEG-1).

TF3C2_MOUSE
θ value	0.62314 (rank : 264)	NC score	0.136553 (rank : 322)
Query Neighborhood Hits	414	Target Neighborhood Hits	165	Shared Neighborhood Hits	89
SwissProt Accessions	Q8BL74, Q3U7Z9, Q80XQ7, Q8BJJ4, Q8BLP3, Q8K1J1, Q9CSS0, Q9CVE6, Q9DBK6	Gene names	Gtf3c2, Kiaa0011
Domain Architecture
Description	General transcription factor 3C polypeptide 2 (Transcription factor IIIC-subunit beta) (TF3C-beta) (TFIIIC 110 kDa subunit) (TFIIIC110).

WDFY2_MOUSE
θ value	0.62314 (rank : 265)	NC score	0.450647 (rank : 201)
Query Neighborhood Hits	414	Target Neighborhood Hits	337	Shared Neighborhood Hits	232
SwissProt Accessions	Q8BUB4	Gene names	Wdfy2
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2).

WDR37_MOUSE
θ value	0.62314 (rank : 266)	NC score	0.597677 (rank : 118)
Query Neighborhood Hits	414	Target Neighborhood Hits	298	Shared Neighborhood Hits	223
SwissProt Accessions	Q8CBE3, Q80Y96, Q8CCL2	Gene names	Wdr37, Kiaa0982
Domain Architecture
Description	WD repeat protein 37.

ACD_MOUSE
θ value	0.813845 (rank : 267)	NC score	0.029224 (rank : 381)
Query Neighborhood Hits	414	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q5EE38, Q3TBB1, Q3TUR7, Q3UKL6, Q3V3Y1, Q99KF8	Gene names	Acd
Domain Architecture	No domain graphic available
Description	Adrenocortical dysplasia protein.

ARC1B_HUMAN
θ value	0.813845 (rank : 268)	NC score	0.311017 (rank : 259)
Query Neighborhood Hits	414	Target Neighborhood Hits	148	Shared Neighborhood Hits	138
SwissProt Accessions	O15143, Q9BU00	Gene names	ARPC1B, ARC41
Domain Architecture
Description	Actin-related protein 2/3 complex subunit 1B (ARP2/3 complex 41 kDa subunit) (p41-ARC).

BRD4_MOUSE
θ value	0.813845 (rank : 269)	NC score	0.025355 (rank : 403)
Query Neighborhood Hits	414	Target Neighborhood Hits	845	Shared Neighborhood Hits	40
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

FBXW5_HUMAN
θ value	0.813845 (rank : 270)	NC score	0.306630 (rank : 260)
Query Neighborhood Hits	414	Target Neighborhood Hits	156	Shared Neighborhood Hits	126
SwissProt Accessions	Q969U6, Q5SPZ8, Q5SPZ9, Q5SQ02, Q5SQ03, Q5SQ04, Q8WY79, Q96GJ6, Q9BSU8, Q9H6A8, Q9HBQ6, Q9NSZ3	Gene names	FBXW5, FBW5
Domain Architecture
Description	F-box/WD repeat protein 5 (F-box and WD-40 domain protein 5).

KI21B_MOUSE
θ value	0.813845 (rank : 271)	NC score	0.256392 (rank : 279)
Query Neighborhood Hits	414	Target Neighborhood Hits	997	Shared Neighborhood Hits	238
SwissProt Accessions	Q9QXL1, P97424	Gene names	Kif21b, Kif6
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B (Kinesin-like protein KIF6).

NFM_HUMAN
θ value	0.813845 (rank : 272)	NC score	0.020742 (rank : 419)
Query Neighborhood Hits	414	Target Neighborhood Hits	1328	Shared Neighborhood Hits	76
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

SRRM2_MOUSE
θ value	0.813845 (rank : 273)	NC score	0.029550 (rank : 380)
Query Neighborhood Hits	414	Target Neighborhood Hits	1470	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TCOF_MOUSE
θ value	0.813845 (rank : 274)	NC score	0.023295 (rank : 411)
Query Neighborhood Hits	414	Target Neighborhood Hits	471	Shared Neighborhood Hits	24
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

THOC6_HUMAN
θ value	0.813845 (rank : 275)	NC score	0.457864 (rank : 198)
Query Neighborhood Hits	414	Target Neighborhood Hits	223	Shared Neighborhood Hits	183
SwissProt Accessions	Q86W42, Q8NBR1, Q9BTV9	Gene names	THOC6, WDR58
Domain Architecture	No domain graphic available
Description	THO complex subunit 6 homolog (WD repeat protein 58).

TTF2_HUMAN
θ value	0.813845 (rank : 276)	NC score	0.012439 (rank : 453)
Query Neighborhood Hits	414	Target Neighborhood Hits	98	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UNY4, O75921, Q5T2K7, Q5VVU8, Q8N6I8	Gene names	TTF2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2) (Factor 2) (F2) (HuF2) (Lodestar homolog).

WDR7_HUMAN
θ value	0.813845 (rank : 277)	NC score	0.363338 (rank : 249)
Query Neighborhood Hits	414	Target Neighborhood Hits	244	Shared Neighborhood Hits	176
SwissProt Accessions	Q9Y4E6, Q86UX5, Q86VP2, Q96PS7	Gene names	WDR7, KIAA0541, TRAG
Domain Architecture	No domain graphic available
Description	WD repeat protein 7 (TGF-beta resistance-associated protein TRAG) (Rabconnectin-3 beta).

AKAP2_MOUSE
θ value	1.06291 (rank : 278)	NC score	0.028892 (rank : 382)
Query Neighborhood Hits	414	Target Neighborhood Hits	385	Shared Neighborhood Hits	29
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

CASP_MOUSE
θ value	1.06291 (rank : 279)	NC score	0.014942 (rank : 443)
Query Neighborhood Hits	414	Target Neighborhood Hits	1152	Shared Neighborhood Hits	52
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CENPC_MOUSE
θ value	1.06291 (rank : 280)	NC score	0.027064 (rank : 389)
Query Neighborhood Hits	414	Target Neighborhood Hits	154	Shared Neighborhood Hits	18
SwissProt Accessions	P49452	Gene names	Cenpc1, Cenpc
Domain Architecture	No domain graphic available
Description	Centromere protein C 1 (CENP-C) (Centromere autoantigen C).

CTR9_MOUSE
θ value	1.06291 (rank : 281)	NC score	0.025570 (rank : 400)
Query Neighborhood Hits	414	Target Neighborhood Hits	427	Shared Neighborhood Hits	24
SwissProt Accessions	Q62018, Q3UFF5, Q3UY40, Q66JX4, Q7TPS6, Q8BND9, Q8BRD1, Q8C9W7, Q8C9Y3, Q8CHI1	Gene names	Ctr9, Kiaa0155, Sh2bp1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) (Tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa) (TPR-containing, SH2-binding phosphoprotein of 150 kDa) (p150TSP).

CUTL1_MOUSE
θ value	1.06291 (rank : 282)	NC score	0.013807 (rank : 448)
Query Neighborhood Hits	414	Target Neighborhood Hits	1620	Shared Neighborhood Hits	66
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

DDEF2_MOUSE
θ value	1.06291 (rank : 283)	NC score	0.007940 (rank : 476)
Query Neighborhood Hits	414	Target Neighborhood Hits	625	Shared Neighborhood Hits	11
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

EDD1_HUMAN
θ value	1.06291 (rank : 284)	NC score	0.024613 (rank : 407)
Query Neighborhood Hits	414	Target Neighborhood Hits	170	Shared Neighborhood Hits	10
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

GNB1L_MOUSE
θ value	1.06291 (rank : 285)	NC score	0.525533 (rank : 159)
Query Neighborhood Hits	414	Target Neighborhood Hits	231	Shared Neighborhood Hits	188
SwissProt Accessions	Q9EQ15, Q8R1F3, Q9CWP2, Q9D3Y1	Gene names	Gnb1l, Estm55, Wdr14
Domain Architecture
Description	Guanine nucleotide-binding protein subunit beta-like protein 1 (G protein subunit beta-like protein 1) (WD40 repeat-containing protein deleted in VCFS) (Protein WDVCF).

MYH10_MOUSE
θ value	1.06291 (rank : 286)	NC score	0.010514 (rank : 463)
Query Neighborhood Hits	414	Target Neighborhood Hits	1612	Shared Neighborhood Hits	59
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH14_HUMAN
θ value	1.06291 (rank : 287)	NC score	0.009467 (rank : 467)
Query Neighborhood Hits	414	Target Neighborhood Hits	995	Shared Neighborhood Hits	35
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

PRP4B_HUMAN
θ value	1.06291 (rank : 288)	NC score	0.001200 (rank : 485)
Query Neighborhood Hits	414	Target Neighborhood Hits	1030	Shared Neighborhood Hits	30
SwissProt Accessions	Q13523, Q8TDP2, Q96QT7, Q9UEE6	Gene names	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (PRP4 kinase).

RAE1L_MOUSE
θ value	1.06291 (rank : 289)	NC score	0.519630 (rank : 165)
Query Neighborhood Hits	414	Target Neighborhood Hits	225	Shared Neighborhood Hits	194
SwissProt Accessions	Q8C570, Q3UKD4	Gene names	Rae1, Mrnp41
Domain Architecture	No domain graphic available
Description	mRNA-associated protein mrnp 41 (Rae1 protein homolog).

SFRS4_HUMAN
θ value	1.06291 (rank : 290)	NC score	0.024777 (rank : 405)
Query Neighborhood Hits	414	Target Neighborhood Hits	384	Shared Neighborhood Hits	26
SwissProt Accessions	Q08170, Q5VXP1, Q9BUA4, Q9UEB5	Gene names	SFRS4, SRP75
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB).

WDR37_HUMAN
θ value	1.06291 (rank : 291)	NC score	0.595939 (rank : 122)
Query Neighborhood Hits	414	Target Neighborhood Hits	303	Shared Neighborhood Hits	222
SwissProt Accessions	Q9Y2I8, Q5SW03, Q9NTJ6	Gene names	WDR37, KIAA0982
Domain Architecture
Description	WD repeat protein 37.

WDR65_HUMAN
θ value	1.06291 (rank : 292)	NC score	0.546600 (rank : 154)
Query Neighborhood Hits	414	Target Neighborhood Hits	238	Shared Neighborhood Hits	203
SwissProt Accessions	Q96MR6, Q5TAI0	Gene names	WDR65
Domain Architecture	No domain graphic available
Description	WD repeat protein 65.

WDR67_HUMAN
θ value	1.06291 (rank : 293)	NC score	0.216523 (rank : 291)
Query Neighborhood Hits	414	Target Neighborhood Hits	782	Shared Neighborhood Hits	154
SwissProt Accessions	Q96DN5, Q3MIR6, Q8TBP9	Gene names	WDR67
Domain Architecture	No domain graphic available
Description	WD repeat protein 67.

AFF4_HUMAN
θ value	1.38821 (rank : 294)	NC score	0.032425 (rank : 374)
Query Neighborhood Hits	414	Target Neighborhood Hits	611	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

CAF1A_HUMAN
θ value	1.38821 (rank : 295)	NC score	0.019341 (rank : 423)
Query Neighborhood Hits	414	Target Neighborhood Hits	750	Shared Neighborhood Hits	36
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CING_HUMAN
θ value	1.38821 (rank : 296)	NC score	0.018275 (rank : 427)
Query Neighborhood Hits	414	Target Neighborhood Hits	1275	Shared Neighborhood Hits	67
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

CIR1A_MOUSE
θ value	1.38821 (rank : 297)	NC score	0.353269 (rank : 252)
Query Neighborhood Hits	414	Target Neighborhood Hits	155	Shared Neighborhood Hits	138
SwissProt Accessions	Q8R2N2, Q62306, Q69Z48, Q6NVG9, Q8VEL5	Gene names	Cirh1a, Kiaa1988, Tex292
Domain Architecture	No domain graphic available
Description	Cirhin (Testis-expressed gene 292 protein).

WDR18_HUMAN
θ value	1.38821 (rank : 298)	NC score	0.547212 (rank : 152)
Query Neighborhood Hits	414	Target Neighborhood Hits	246	Shared Neighborhood Hits	207
SwissProt Accessions	Q9BV38, O60390, Q9BWR2	Gene names	WDR18
Domain Architecture
Description	WD repeat protein 18.

WDR34_HUMAN
θ value	1.38821 (rank : 299)	NC score	0.152825 (rank : 311)
Query Neighborhood Hits	414	Target Neighborhood Hits	100	Shared Neighborhood Hits	79
SwissProt Accessions	Q96EX3, Q5VXV4, Q9BV46	Gene names	WDR34
Domain Architecture
Description	WD repeat protein 34.

WDR49_HUMAN
θ value	1.38821 (rank : 300)	NC score	0.511045 (rank : 174)
Query Neighborhood Hits	414	Target Neighborhood Hits	214	Shared Neighborhood Hits	174
SwissProt Accessions	Q8IV35, Q8N297	Gene names	WDR49
Domain Architecture	No domain graphic available
Description	WD repeat protein 49.

ANLN_HUMAN
θ value	1.81305 (rank : 301)	NC score	0.030184 (rank : 379)
Query Neighborhood Hits	414	Target Neighborhood Hits	222	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NQW6, Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0	Gene names	ANLN
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

BUB3_HUMAN
θ value	1.81305 (rank : 302)	NC score	0.457893 (rank : 197)
Query Neighborhood Hits	414	Target Neighborhood Hits	200	Shared Neighborhood Hits	169
SwissProt Accessions	O43684, O43685	Gene names	BUB3
Domain Architecture
Description	Mitotic checkpoint protein BUB3.

BUB3_MOUSE
θ value	1.81305 (rank : 303)	NC score	0.448055 (rank : 204)
Query Neighborhood Hits	414	Target Neighborhood Hits	199	Shared Neighborhood Hits	169
SwissProt Accessions	Q9WVA3, P97397	Gene names	Bub3
Domain Architecture
Description	Mitotic checkpoint protein BUB3 (WD repeat type I transmembrane protein A72.5).

E41LA_HUMAN
θ value	1.81305 (rank : 304)	NC score	0.014055 (rank : 447)
Query Neighborhood Hits	414	Target Neighborhood Hits	87	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HCS5	Gene names	EPB41L4A, EPB41L4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

MINT_HUMAN
θ value	1.81305 (rank : 305)	NC score	0.024409 (rank : 408)
Query Neighborhood Hits	414	Target Neighborhood Hits	1291	Shared Neighborhood Hits	73
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MYH10_HUMAN
θ value	1.81305 (rank : 306)	NC score	0.010015 (rank : 465)
Query Neighborhood Hits	414	Target Neighborhood Hits	1620	Shared Neighborhood Hits	62
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

PCDGC_HUMAN
θ value	1.81305 (rank : 307)	NC score	-0.001906 (rank : 490)
Query Neighborhood Hits	414	Target Neighborhood Hits	155	Shared Neighborhood Hits	2
SwissProt Accessions	O60330, O15100, Q6UW70, Q9Y5D7	Gene names	PCDHGA12, CDH21, FIB3, KIAA0588
Domain Architecture
Description	Protocadherin gamma A12 precursor (PCDH-gamma-A12) (Cadherin-21) (Fibroblast cadherin 3).

SFRIP_HUMAN
θ value	1.81305 (rank : 308)	NC score	0.045541 (rank : 364)
Query Neighborhood Hits	414	Target Neighborhood Hits	530	Shared Neighborhood Hits	50
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

THOC2_HUMAN
θ value	1.81305 (rank : 309)	NC score	0.032352 (rank : 375)
Query Neighborhood Hits	414	Target Neighborhood Hits	337	Shared Neighborhood Hits	36
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

TSH3_HUMAN
θ value	1.81305 (rank : 310)	NC score	0.009523 (rank : 466)
Query Neighborhood Hits	414	Target Neighborhood Hits	564	Shared Neighborhood Hits	8
SwissProt Accessions	Q63HK5, Q9H0G6, Q9P254	Gene names	TSHZ3, KIAA1474, TSH3, ZNF537
Domain Architecture	No domain graphic available
Description	Teashirt homolog 3 (Zinc finger protein 537).

WDR55_HUMAN
θ value	1.81305 (rank : 311)	NC score	0.564133 (rank : 141)
Query Neighborhood Hits	414	Target Neighborhood Hits	231	Shared Neighborhood Hits	197
SwissProt Accessions	Q9H6Y2	Gene names	WDR55
Domain Architecture	No domain graphic available
Description	WD repeat protein 55.

BRD4_HUMAN
θ value	2.36792 (rank : 312)	NC score	0.023404 (rank : 410)
Query Neighborhood Hits	414	Target Neighborhood Hits	851	Shared Neighborhood Hits	41
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

CHD1_HUMAN
θ value	2.36792 (rank : 313)	NC score	0.011182 (rank : 458)
Query Neighborhood Hits	414	Target Neighborhood Hits	337	Shared Neighborhood Hits	28
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

HPS5_HUMAN
θ value	2.36792 (rank : 314)	NC score	0.050679 (rank : 359)
Query Neighborhood Hits	414	Target Neighborhood Hits	51	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UPZ3, O95942, Q8N4U0	Gene names	HPS5, AIBP63, KIAA1017
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 5 protein (Alpha-integrin-binding protein 63) (Ruby-eye protein 2 homolog) (Ru2).

LBXCO_HUMAN
θ value	2.36792 (rank : 315)	NC score	0.025547 (rank : 401)
Query Neighborhood Hits	414	Target Neighborhood Hits	167	Shared Neighborhood Hits	8
SwissProt Accessions	P84550	Gene names	LBXCOR1
Domain Architecture	No domain graphic available
Description	Ladybird homeobox corepressor 1.

LBXCO_MOUSE
θ value	2.36792 (rank : 316)	NC score	0.025865 (rank : 398)
Query Neighborhood Hits	414	Target Neighborhood Hits	140	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BX46, Q3UYA4, Q5W8I2, Q8C0T2	Gene names	Lbxcor1, Corl1
Domain Architecture	No domain graphic available
Description	Ladybird homeobox corepressor 1 (Transcriptional corepressor Corl1).

NFH_HUMAN
θ value	2.36792 (rank : 317)	NC score	0.015797 (rank : 438)
Query Neighborhood Hits	414	Target Neighborhood Hits	1242	Shared Neighborhood Hits	74
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PRG4_HUMAN
θ value	2.36792 (rank : 318)	NC score	0.011483 (rank : 456)
Query Neighborhood Hits	414	Target Neighborhood Hits	764	Shared Neighborhood Hits	40
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PWP1_HUMAN
θ value	2.36792 (rank : 319)	NC score	0.517707 (rank : 167)
Query Neighborhood Hits	414	Target Neighborhood Hits	261	Shared Neighborhood Hits	210
SwissProt Accessions	Q13610	Gene names	PWP1
Domain Architecture
Description	Periodic tryptophan protein 1 homolog (Keratinocyte protein IEF SSP 9502).

RPGR_HUMAN
θ value	2.36792 (rank : 320)	NC score	0.022885 (rank : 413)
Query Neighborhood Hits	414	Target Neighborhood Hits	279	Shared Neighborhood Hits	29
SwissProt Accessions	Q92834, O00702, O00737, Q8N5T6, Q93039, Q9HD29, Q9UMR1	Gene names	RPGR, RP3, XLRP3
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator.

RRMJ3_MOUSE
θ value	2.36792 (rank : 321)	NC score	0.022014 (rank : 416)
Query Neighborhood Hits	414	Target Neighborhood Hits	163	Shared Neighborhood Hits	11
SwissProt Accessions	Q9DBE9, Q3ULI1, Q921I7	Gene names	Ftsj3
Domain Architecture	No domain graphic available
Description	Putative rRNA methyltransferase 3 (EC 2.1.1.-) (rRNA (uridine-2'-O-)- methyltransferase 3).

SOX17_HUMAN
θ value	2.36792 (rank : 322)	NC score	0.027720 (rank : 387)
Query Neighborhood Hits	414	Target Neighborhood Hits	108	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H6I2	Gene names	SOX17
Domain Architecture
Description	Transcription factor SOX-17.

SOX30_HUMAN
θ value	2.36792 (rank : 323)	NC score	0.031334 (rank : 377)
Query Neighborhood Hits	414	Target Neighborhood Hits	305	Shared Neighborhood Hits	32
SwissProt Accessions	O94993, O94995, Q8IYX6	Gene names	SOX30
Domain Architecture
Description	Transcription factor SOX-30.

WDR79_HUMAN
θ value	2.36792 (rank : 324)	NC score	0.464445 (rank : 195)
Query Neighborhood Hits	414	Target Neighborhood Hits	246	Shared Neighborhood Hits	170
SwissProt Accessions	Q9BUR4, Q9NW09	Gene names	WDR79
Domain Architecture	No domain graphic available
Description	WD repeat protein 79.

ARC1B_MOUSE
θ value	3.0926 (rank : 325)	NC score	0.288517 (rank : 267)
Query Neighborhood Hits	414	Target Neighborhood Hits	133	Shared Neighborhood Hits	124
SwissProt Accessions	Q9WV32	Gene names	Arpc1b
Domain Architecture
Description	Actin-related protein 2/3 complex subunit 1B (ARP2/3 complex 41 kDa subunit) (p41-ARC).

DPOLZ_HUMAN
θ value	3.0926 (rank : 326)	NC score	0.016350 (rank : 435)
Query Neighborhood Hits	414	Target Neighborhood Hits	200	Shared Neighborhood Hits	21
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

FYV1_HUMAN
θ value	3.0926 (rank : 327)	NC score	0.012883 (rank : 451)
Query Neighborhood Hits	414	Target Neighborhood Hits	217	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

LYRIC_MOUSE
θ value	3.0926 (rank : 328)	NC score	0.042374 (rank : 367)
Query Neighborhood Hits	414	Target Neighborhood Hits	126	Shared Neighborhood Hits	20
SwissProt Accessions	Q80WJ7, Q3U9F8, Q3UAQ8, Q8BN67, Q8CBT9, Q8CDL0, Q8CGI7, Q9D052	Gene names	Mtdh, Lyric
Domain Architecture	No domain graphic available
Description	Protein LYRIC (Lysine-rich CEACAM1 co-isolated protein) (3D3/LYRIC) (Metastasis adhesion protein) (Metadherin).

SOX15_MOUSE
θ value	3.0926 (rank : 329)	NC score	0.030556 (rank : 378)
Query Neighborhood Hits	414	Target Neighborhood Hits	100	Shared Neighborhood Hits	20
SwissProt Accessions	P43267, O70204, P70418, Q62246, Q91V00, Q91V43, Q920T1, Q9JLG2	Gene names	Sox15, Sox-15
Domain Architecture
Description	SOX-15 protein.

WDR20_HUMAN
θ value	3.0926 (rank : 330)	NC score	0.397891 (rank : 220)
Query Neighborhood Hits	414	Target Neighborhood Hits	249	Shared Neighborhood Hits	185
SwissProt Accessions	Q8TBZ3, Q8WXX2, Q9UF86	Gene names	WDR20
Domain Architecture
Description	WD repeat protein 20 (DMR protein).

ZF106_HUMAN
θ value	3.0926 (rank : 331)	NC score	0.426485 (rank : 210)
Query Neighborhood Hits	414	Target Neighborhood Hits	470	Shared Neighborhood Hits	189
SwissProt Accessions	Q9H2Y7, Q6NSD9, Q6PEK1, Q86T43, Q86T45, Q86T50, Q86T58, Q86TA9, Q96M37, Q9H7B8	Gene names	ZFP106, ZNF474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 homolog (Zfp-106) (Zinc finger protein 474).

ZN318_HUMAN
θ value	3.0926 (rank : 332)	NC score	0.021837 (rank : 418)
Query Neighborhood Hits	414	Target Neighborhood Hits	497	Shared Neighborhood Hits	30
SwissProt Accessions	Q5VUA4, O94796, Q4G0E4, Q8NEM6, Q9UNU8, Q9Y2W9	Gene names	ZNF318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Endocrine regulatory protein).

ZRF1_HUMAN
θ value	3.0926 (rank : 333)	NC score	0.018746 (rank : 426)
Query Neighborhood Hits	414	Target Neighborhood Hits	457	Shared Neighborhood Hits	21
SwissProt Accessions	Q99543	Gene names	ZRF1, DNAJC2, MPHOSPH11, MPP11
Domain Architecture
Description	Zuotin-related factor 1 (M-phase phosphoprotein 11).

ARMX5_HUMAN
θ value	4.03905 (rank : 334)	NC score	0.009330 (rank : 468)
Query Neighborhood Hits	414	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P1M9, Q68DB4, Q9BVZ3, Q9H969	Gene names	ARMCX5
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 5.

DEK_MOUSE
θ value	4.03905 (rank : 335)	NC score	0.020684 (rank : 420)
Query Neighborhood Hits	414	Target Neighborhood Hits	280	Shared Neighborhood Hits	17
SwissProt Accessions	Q7TNV0, Q80VC5, Q8BZV6	Gene names	Dek
Domain Architecture	No domain graphic available
Description	Protein DEK.

ELK3_MOUSE
θ value	4.03905 (rank : 336)	NC score	0.004178 (rank : 482)
Query Neighborhood Hits	414	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	P41971, P97747, Q62346	Gene names	Elk3, Erp, Net
Domain Architecture
Description	ETS domain-containing protein Elk-3 (ETS-related protein NET) (ETS- related protein ERP).

EMAL2_HUMAN
θ value	4.03905 (rank : 337)	NC score	0.480501 (rank : 188)
Query Neighborhood Hits	414	Target Neighborhood Hits	217	Shared Neighborhood Hits	188
SwissProt Accessions	O95834, Q9UG50	Gene names	EML2, EMAP2, EMAPL2
Domain Architecture
Description	Echinoderm microtubule-associated protein-like 2 (EMAP-2) (HuEMAP-2).

EST1A_MOUSE
θ value	4.03905 (rank : 338)	NC score	0.016125 (rank : 436)
Query Neighborhood Hits	414	Target Neighborhood Hits	138	Shared Neighborhood Hits	13
SwissProt Accessions	P61406, Q5NC64	Gene names	Est1a, Kiaa0732
Domain Architecture
Description	Telomerase-binding protein EST1A (Ever shorter telomeres 1A) (Telomerase subunit EST1A) (EST1-like protein A).

MUC15_HUMAN
θ value	4.03905 (rank : 339)	NC score	0.015714 (rank : 439)
Query Neighborhood Hits	414	Target Neighborhood Hits	61	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N387, Q6UWS3, Q8IXI8, Q8WW41	Gene names	MUC15
Domain Architecture	No domain graphic available
Description	Mucin-15 precursor.

MYO9B_MOUSE
θ value	4.03905 (rank : 340)	NC score	0.006120 (rank : 479)
Query Neighborhood Hits	414	Target Neighborhood Hits	311	Shared Neighborhood Hits	16
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

MYPT2_HUMAN
θ value	4.03905 (rank : 341)	NC score	0.000894 (rank : 486)
Query Neighborhood Hits	414	Target Neighborhood Hits	707	Shared Neighborhood Hits	32
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

SMC3_HUMAN
θ value	4.03905 (rank : 342)	NC score	0.017600 (rank : 431)
Query Neighborhood Hits	414	Target Neighborhood Hits	1186	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

SMC3_MOUSE
θ value	4.03905 (rank : 343)	NC score	0.017647 (rank : 430)
Query Neighborhood Hits	414	Target Neighborhood Hits	1187	Shared Neighborhood Hits	64
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

SOX30_MOUSE
θ value	4.03905 (rank : 344)	NC score	0.027486 (rank : 388)
Query Neighborhood Hits	414	Target Neighborhood Hits	374	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

ST5_HUMAN
θ value	4.03905 (rank : 345)	NC score	0.006616 (rank : 478)
Query Neighborhood Hits	414	Target Neighborhood Hits	151	Shared Neighborhood Hits	8
SwissProt Accessions	P78524, P78523, Q16492, Q7KYY2, Q7KZ12, Q8NE12, Q9BQQ6	Gene names	ST5, DENND2B, HTS1
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (HeLa tumor suppression 1) (DENN domain-containing protein 2B).

TSH3_MOUSE
θ value	4.03905 (rank : 346)	NC score	0.008522 (rank : 475)
Query Neighborhood Hits	414	Target Neighborhood Hits	590	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CGV9, Q5DTX4	Gene names	Tshz3, Kiaa1474, Tsh3, Zfp537, Znf537
Domain Architecture	No domain graphic available
Description	Teashirt homolog 3 (Zinc finger protein 537).

TTF1_HUMAN
θ value	4.03905 (rank : 347)	NC score	0.015391 (rank : 441)
Query Neighborhood Hits	414	Target Neighborhood Hits	68	Shared Neighborhood Hits	7
SwissProt Accessions	Q15361, Q4VXF3, Q58EY2, Q6P5T5	Gene names	TTF1
Domain Architecture	No domain graphic available
Description	Transcription termination factor 1 (TTF-1) (TTF-I) (RNA polymerase I termination factor).

WDR79_MOUSE
θ value	4.03905 (rank : 348)	NC score	0.490729 (rank : 182)
Query Neighborhood Hits	414	Target Neighborhood Hits	216	Shared Neighborhood Hits	176
SwissProt Accessions	Q8VC51	Gene names	Wdr79
Domain Architecture	No domain graphic available
Description	WD repeat protein 79.

ZCHC7_HUMAN
θ value	4.03905 (rank : 349)	NC score	0.020250 (rank : 422)
Query Neighborhood Hits	414	Target Neighborhood Hits	73	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N3Z6, Q5T0Q8, Q5T0Q9, Q5T0R0, Q8N2M1, Q8N4J2, Q8TBK8, Q9H648, Q9P0F0	Gene names	ZCCHC7
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 7.

ZF106_MOUSE
θ value	4.03905 (rank : 350)	NC score	0.413604 (rank : 213)
Query Neighborhood Hits	414	Target Neighborhood Hits	472	Shared Neighborhood Hits	190
SwissProt Accessions	O88466, O55185, O88465, O88467, Q792M1, Q792P4, Q8CDZ8, Q8R3I4, Q9ESU3	Gene names	Zfp106, H3a, Sh3bp3, Sirm, Znf474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 (Zfp-106) (Zinc finger protein 474) (H3a minor histocompatibility antigen) (Son of insulin receptor mutant).

ZRF1_MOUSE
θ value	4.03905 (rank : 351)	NC score	0.017675 (rank : 429)
Query Neighborhood Hits	414	Target Neighborhood Hits	414	Shared Neighborhood Hits	21
SwissProt Accessions	P54103	Gene names	Zrf1, Dnajc2
Domain Architecture
Description	Zuotin-related factor 1.

AFF1_HUMAN
θ value	5.27518 (rank : 352)	NC score	0.019239 (rank : 424)
Query Neighborhood Hits	414	Target Neighborhood Hits	506	Shared Neighborhood Hits	37
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

AN30A_HUMAN
θ value	5.27518 (rank : 353)	NC score	0.011060 (rank : 459)
Query Neighborhood Hits	414	Target Neighborhood Hits	1119	Shared Neighborhood Hits	68
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

COR2B_MOUSE
θ value	5.27518 (rank : 354)	NC score	0.393471 (rank : 226)
Query Neighborhood Hits	414	Target Neighborhood Hits	235	Shared Neighborhood Hits	196
SwissProt Accessions	Q8BH44, Q6P5U9	Gene names	Coro2b
Domain Architecture	No domain graphic available
Description	Coronin-2B.

DNM3B_MOUSE
θ value	5.27518 (rank : 355)	NC score	0.007831 (rank : 477)
Query Neighborhood Hits	414	Target Neighborhood Hits	61	Shared Neighborhood Hits	7
SwissProt Accessions	O88509, O88510, O88511	Gene names	Dnmt3b
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3B (EC 2.1.1.37) (Dnmt3b) (DNA methyltransferase MmuIIIB) (DNA MTase MmuIIIB) (M.MmuIIIB).

GDE5_MOUSE
θ value	5.27518 (rank : 356)	NC score	0.011393 (rank : 457)
Query Neighborhood Hits	414	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C0L9, Q3TLV6, Q80TD5, Q8BKJ7, Q8BKW7, Q8CFW2, Q9D759	Gene names	Gde5, Kiaa1434, Prei4
Domain Architecture	No domain graphic available
Description	Putative glycerophosphodiester phosphodiesterase 5 (EC 3.1.-.-) (Preimplantation protein 4).

IF140_HUMAN
θ value	5.27518 (rank : 357)	NC score	0.150303 (rank : 312)
Query Neighborhood Hits	414	Target Neighborhood Hits	111	Shared Neighborhood Hits	77
SwissProt Accessions	Q96RY7, O60332	Gene names	IFT140, KIAA0590, WDTC2
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 140 homolog (WD and tetratricopeptide repeats protein 2).

IF2P_HUMAN
θ value	5.27518 (rank : 358)	NC score	0.014440 (rank : 445)
Query Neighborhood Hits	414	Target Neighborhood Hits	889	Shared Neighborhood Hits	51
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

LZTS1_HUMAN
θ value	5.27518 (rank : 359)	NC score	0.018954 (rank : 425)
Query Neighborhood Hits	414	Target Neighborhood Hits	532	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y250, Q9Y5V7, Q9Y5V8, Q9Y5V9, Q9Y5W0, Q9Y5W1, Q9Y5W2	Gene names	LZTS1, FEZ1
Domain Architecture
Description	Leucine zipper putative tumor suppressor 1 (F37/esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

SYTL5_MOUSE
θ value	5.27518 (rank : 360)	NC score	0.004761 (rank : 481)
Query Neighborhood Hits	414	Target Neighborhood Hits	154	Shared Neighborhood Hits	5
SwissProt Accessions	Q80T23, Q812E5	Gene names	Sytl5, Slp5
Domain Architecture
Description	Synaptotagmin-like protein 5.

UBF1_HUMAN
θ value	5.27518 (rank : 361)	NC score	0.039609 (rank : 368)
Query Neighborhood Hits	414	Target Neighborhood Hits	415	Shared Neighborhood Hits	51
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

WD21C_HUMAN
θ value	5.27518 (rank : 362)	NC score	0.340864 (rank : 253)
Query Neighborhood Hits	414	Target Neighborhood Hits	157	Shared Neighborhood Hits	133
SwissProt Accessions	Q8NA75	Gene names	WDR21C
Domain Architecture	No domain graphic available
Description	WD repeat protein 21C.

WDR20_MOUSE
θ value	5.27518 (rank : 363)	NC score	0.406520 (rank : 216)
Query Neighborhood Hits	414	Target Neighborhood Hits	217	Shared Neighborhood Hits	177
SwissProt Accessions	Q9D5R2	Gene names	Wdr20
Domain Architecture
Description	WD repeat protein 20.

WDR46_MOUSE
θ value	5.27518 (rank : 364)	NC score	0.208065 (rank : 294)
Query Neighborhood Hits	414	Target Neighborhood Hits	243	Shared Neighborhood Hits	103
SwissProt Accessions	Q9Z0H1	Gene names	Wdr46, Bing4
Domain Architecture
Description	WD repeat protein 46 (WD repeat protein BING4).

CBP_HUMAN
θ value	6.88961 (rank : 365)	NC score	0.022007 (rank : 417)
Query Neighborhood Hits	414	Target Neighborhood Hits	941	Shared Neighborhood Hits	36
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CDSN_MOUSE
θ value	6.88961 (rank : 366)	NC score	0.010373 (rank : 464)
Query Neighborhood Hits	414	Target Neighborhood Hits	131	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TPC1	Gene names	Cdsn
Domain Architecture	No domain graphic available
Description	Corneodesmosin precursor.

COR1A_MOUSE
θ value	6.88961 (rank : 367)	NC score	0.391889 (rank : 228)
Query Neighborhood Hits	414	Target Neighborhood Hits	243	Shared Neighborhood Hits	192
SwissProt Accessions	O89053, Q7TMU0, Q9R1Y8, Q9R288	Gene names	Coro1a, Coro1
Domain Architecture
Description	Coronin-1A (Coronin-like protein p57) (Coronin-like protein A) (CLIPINA) (Tryptophan aspartate-containing coat protein) (TACO).

ESPL1_HUMAN
θ value	6.88961 (rank : 368)	NC score	0.009164 (rank : 472)
Query Neighborhood Hits	414	Target Neighborhood Hits	95	Shared Neighborhood Hits	5
SwissProt Accessions	Q14674	Gene names	ESPL1, ESP1, KIAA0165
Domain Architecture
Description	Separin (EC 3.4.22.49) (Separase) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein).

G3BP_HUMAN
θ value	6.88961 (rank : 369)	NC score	0.004938 (rank : 480)
Query Neighborhood Hits	414	Target Neighborhood Hits	219	Shared Neighborhood Hits	6
SwissProt Accessions	Q13283	Gene names	G3BP, G3BP1
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 1 (EC 3.6.1.-) (ATP- dependent DNA helicase VIII) (GAP SH3-domain-binding protein 1) (G3BP- 1) (HDH-VIII).

HRX_HUMAN
θ value	6.88961 (rank : 370)	NC score	0.013564 (rank : 450)
Query Neighborhood Hits	414	Target Neighborhood Hits	825	Shared Neighborhood Hits	50
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

IF32_HUMAN
θ value	6.88961 (rank : 371)	NC score	0.533035 (rank : 158)
Query Neighborhood Hits	414	Target Neighborhood Hits	239	Shared Neighborhood Hits	197
SwissProt Accessions	Q13347	Gene names	EIF3S2, TRIP1
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 2 (eIF-3 beta) (eIF3 p36) (eIF3i) (TGF-beta receptor-interacting protein 1) (TRIP-1).

INCE_MOUSE
θ value	6.88961 (rank : 372)	NC score	0.010725 (rank : 462)
Query Neighborhood Hits	414	Target Neighborhood Hits	903	Shared Neighborhood Hits	40
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

LAMA4_HUMAN
θ value	6.88961 (rank : 373)	NC score	0.000077 (rank : 488)
Query Neighborhood Hits	414	Target Neighborhood Hits	708	Shared Neighborhood Hits	21
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

MLL3_HUMAN
θ value	6.88961 (rank : 374)	NC score	0.009204 (rank : 470)
Query Neighborhood Hits	414	Target Neighborhood Hits	1644	Shared Neighborhood Hits	57
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MYST3_MOUSE
θ value	6.88961 (rank : 375)	NC score	0.011057 (rank : 460)
Query Neighborhood Hits	414	Target Neighborhood Hits	688	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

NELFA_MOUSE
θ value	6.88961 (rank : 376)	NC score	0.011736 (rank : 455)
Query Neighborhood Hits	414	Target Neighborhood Hits	195	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BG30, Q8BVE4, Q8VEI7, Q9CSJ9, Q9Z1V9	Gene names	Whsc2, Nelfa, Whsc2h
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 homolog) (mWHSC2).

RB6I2_HUMAN
θ value	6.88961 (rank : 377)	NC score	0.012030 (rank : 454)
Query Neighborhood Hits	414	Target Neighborhood Hits	1584	Shared Neighborhood Hits	69
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

RFWD2_HUMAN
θ value	6.88961 (rank : 378)	NC score	0.457947 (rank : 196)
Query Neighborhood Hits	414	Target Neighborhood Hits	518	Shared Neighborhood Hits	204
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

RFWD2_MOUSE
θ value	6.88961 (rank : 379)	NC score	0.456794 (rank : 199)
Query Neighborhood Hits	414	Target Neighborhood Hits	535	Shared Neighborhood Hits	203
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

SFR11_HUMAN
θ value	6.88961 (rank : 380)	NC score	0.025739 (rank : 399)
Query Neighborhood Hits	414	Target Neighborhood Hits	246	Shared Neighborhood Hits	23
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

SOX14_HUMAN
θ value	6.88961 (rank : 381)	NC score	0.026710 (rank : 390)
Query Neighborhood Hits	414	Target Neighborhood Hits	102	Shared Neighborhood Hits	21
SwissProt Accessions	O95416, Q3KPH7	Gene names	SOX14, SOX28
Domain Architecture
Description	Transcription factor SOX-14.

SOX14_MOUSE
θ value	6.88961 (rank : 382)	NC score	0.026556 (rank : 391)
Query Neighborhood Hits	414	Target Neighborhood Hits	100	Shared Neighborhood Hits	21
SwissProt Accessions	Q04892, Q9JLC9, Q9JLD0, Q9QXU4	Gene names	Sox14, Sox-14
Domain Architecture
Description	Transcription factor SOX-14.

SOX17_MOUSE
θ value	6.88961 (rank : 383)	NC score	0.024758 (rank : 406)
Query Neighborhood Hits	414	Target Neighborhood Hits	223	Shared Neighborhood Hits	20
SwissProt Accessions	Q61473, Q61472, Q62248	Gene names	Sox17, Sox-17
Domain Architecture
Description	Transcription factor SOX-17.

SOX1_HUMAN
θ value	6.88961 (rank : 384)	NC score	0.026475 (rank : 392)
Query Neighborhood Hits	414	Target Neighborhood Hits	90	Shared Neighborhood Hits	20
SwissProt Accessions	O00570	Gene names	SOX1
Domain Architecture
Description	SOX-1 protein.

SOX1_MOUSE
θ value	6.88961 (rank : 385)	NC score	0.026410 (rank : 393)
Query Neighborhood Hits	414	Target Neighborhood Hits	90	Shared Neighborhood Hits	20
SwissProt Accessions	P53783	Gene names	Sox1, Sox-1
Domain Architecture
Description	SOX-1 protein.

TAXB1_HUMAN
θ value	6.88961 (rank : 386)	NC score	0.009196 (rank : 471)
Query Neighborhood Hits	414	Target Neighborhood Hits	829	Shared Neighborhood Hits	36
SwissProt Accessions	Q86VP1, O60398, O95770, Q13311, Q9BQG5, Q9UI88	Gene names	TAX1BP1, T6BP
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 (TRAF6-binding protein).

TEX9_HUMAN
θ value	6.88961 (rank : 387)	NC score	0.008817 (rank : 474)
Query Neighborhood Hits	414	Target Neighborhood Hits	541	Shared Neighborhood Hits	33
SwissProt Accessions	Q8N6V9	Gene names	TEX9
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 9 protein.

TFG_HUMAN
θ value	6.88961 (rank : 388)	NC score	0.016668 (rank : 434)
Query Neighborhood Hits	414	Target Neighborhood Hits	122	Shared Neighborhood Hits	7
SwissProt Accessions	Q92734, Q15656	Gene names	TFG
Domain Architecture
Description	Protein TFG (TRK-fused gene protein).

WDR24_HUMAN
θ value	6.88961 (rank : 389)	NC score	0.384140 (rank : 231)
Query Neighborhood Hits	414	Target Neighborhood Hits	247	Shared Neighborhood Hits	190
SwissProt Accessions	Q96S15, Q96GC7, Q9H0B7	Gene names	WDR24
Domain Architecture	No domain graphic available
Description	WD repeat protein 24.

ABTAP_MOUSE
θ value	8.99809 (rank : 390)	NC score	0.015192 (rank : 442)
Query Neighborhood Hits	414	Target Neighborhood Hits	381	Shared Neighborhood Hits	32
SwissProt Accessions	Q3V1V3	Gene names	Abtap
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

ASXL1_HUMAN
θ value	8.99809 (rank : 391)	NC score	0.013783 (rank : 449)
Query Neighborhood Hits	414	Target Neighborhood Hits	260	Shared Neighborhood Hits	22
SwissProt Accessions	Q8IXJ9, Q5JWS9, Q8IYY7, Q9H466, Q9NQF8, Q9UFJ0, Q9UFP8, Q9Y2I4	Gene names	ASXL1, KIAA0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

ATBF1_MOUSE
θ value	8.99809 (rank : 392)	NC score	-0.005779 (rank : 492)
Query Neighborhood Hits	414	Target Neighborhood Hits	1841	Shared Neighborhood Hits	56
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

BAZ1A_HUMAN
θ value	8.99809 (rank : 393)	NC score	0.022837 (rank : 414)
Query Neighborhood Hits	414	Target Neighborhood Hits	693	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

CEP35_HUMAN
θ value	8.99809 (rank : 394)	NC score	0.016041 (rank : 437)
Query Neighborhood Hits	414	Target Neighborhood Hits	811	Shared Neighborhood Hits	57
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

CLSPN_MOUSE
θ value	8.99809 (rank : 395)	NC score	0.014700 (rank : 444)
Query Neighborhood Hits	414	Target Neighborhood Hits	292	Shared Neighborhood Hits	26
SwissProt Accessions	Q80YR7, Q69GM2	Gene names	Clspn
Domain Architecture	No domain graphic available
Description	Claspin.

COR1B_HUMAN
θ value	8.99809 (rank : 396)	NC score	0.370720 (rank : 242)
Query Neighborhood Hits	414	Target Neighborhood Hits	239	Shared Neighborhood Hits	195
SwissProt Accessions	Q9BR76	Gene names	CORO1B
Domain Architecture
Description	Coronin-1B (Coronin-2).

DMWD_MOUSE
θ value	8.99809 (rank : 397)	NC score	0.397666 (rank : 221)
Query Neighborhood Hits	414	Target Neighborhood Hits	282	Shared Neighborhood Hits	178
SwissProt Accessions	Q08274	Gene names	Dmwd, Dm9
Domain Architecture
Description	Dystrophia myotonica WD repeat-containing protein (Dystrophia myotonica-containing WD repeat motif protein) (DMR-N9 protein).

GAK_MOUSE
θ value	8.99809 (rank : 398)	NC score	-0.008148 (rank : 493)
Query Neighborhood Hits	414	Target Neighborhood Hits	964	Shared Neighborhood Hits	16
SwissProt Accessions	Q99KY4, Q6P1I8, Q6P9S5, Q8BM74, Q8K0Q4	Gene names	Gak
Domain Architecture	No domain graphic available
Description	Cyclin G-associated kinase (EC 2.7.11.1).

IF32_MOUSE
θ value	8.99809 (rank : 399)	NC score	0.533114 (rank : 157)
Query Neighborhood Hits	414	Target Neighborhood Hits	239	Shared Neighborhood Hits	197
SwissProt Accessions	Q9QZD9	Gene names	Eif3s2, Trip1
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 2 (eIF-3 beta) (eIF3 p36) (eIF3i) (TGF-beta receptor-interacting protein 1) (TRIP-1).

IFT81_MOUSE
θ value	8.99809 (rank : 400)	NC score	0.009251 (rank : 469)
Query Neighborhood Hits	414	Target Neighborhood Hits	959	Shared Neighborhood Hits	48
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

K0586_HUMAN
θ value	8.99809 (rank : 401)	NC score	0.012727 (rank : 452)
Query Neighborhood Hits	414	Target Neighborhood Hits	311	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BVV6, O60328	Gene names	KIAA0586
Domain Architecture	No domain graphic available
Description	Protein KIAA0586.

MAGD1_HUMAN
θ value	8.99809 (rank : 402)	NC score	0.001248 (rank : 484)
Query Neighborhood Hits	414	Target Neighborhood Hits	130	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y5V3, Q5VSH6, Q8IZ84, Q8WY92, Q9H352, Q9HBT4, Q9UF36	Gene names	MAGED1, NRAGE
Domain Architecture
Description	Melanoma-associated antigen D1 (MAGE-D1 antigen) (Neurotrophin receptor-interacting MAGE homolog) (MAGE tumor antigen CCF).

P52K_HUMAN
θ value	8.99809 (rank : 403)	NC score	0.009093 (rank : 473)
Query Neighborhood Hits	414	Target Neighborhood Hits	142	Shared Neighborhood Hits	10
SwissProt Accessions	O43422, Q8WTW1, Q9Y3Z4	Gene names	PRKRIR, DAP4, P52RIPK, THAP0
Domain Architecture
Description	52 kDa repressor of the inhibitor of the protein kinase (p58IPK- interacting protein) (58 kDa interferon-induced protein kinase- interacting protein) (P52rIPK) (Death-associated protein 4) (THAP domain-containing protein 0).

PWP1_MOUSE
θ value	8.99809 (rank : 404)	NC score	0.525442 (rank : 160)
Query Neighborhood Hits	414	Target Neighborhood Hits	278	Shared Neighborhood Hits	212
SwissProt Accessions	Q99LL5, Q9D6T6	Gene names	Pwp1
Domain Architecture	No domain graphic available
Description	Periodic tryptophan protein 1 homolog.

RAI14_HUMAN
θ value	8.99809 (rank : 405)	NC score	-0.000559 (rank : 489)
Query Neighborhood Hits	414	Target Neighborhood Hits	1367	Shared Neighborhood Hits	45
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

RB6I2_MOUSE
θ value	8.99809 (rank : 406)	NC score	0.010758 (rank : 461)
Query Neighborhood Hits	414	Target Neighborhood Hits	1433	Shared Neighborhood Hits	60
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

RRMJ3_HUMAN
θ value	8.99809 (rank : 407)	NC score	0.015454 (rank : 440)
Query Neighborhood Hits	414	Target Neighborhood Hits	88	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IY81, Q8N3A3, Q8WXX1, Q9BWM4, Q9NXT6	Gene names	FTSJ3
Domain Architecture	No domain graphic available
Description	Putative rRNA methyltransferase 3 (EC 2.1.1.-) (rRNA (uridine-2'-O-)- methyltransferase 3).

SOX2_HUMAN
θ value	8.99809 (rank : 408)	NC score	0.026087 (rank : 396)
Query Neighborhood Hits	414	Target Neighborhood Hits	89	Shared Neighborhood Hits	22
SwissProt Accessions	P48431, Q14537	Gene names	SOX2
Domain Architecture
Description	Transcription factor SOX-2.

SOX2_MOUSE
θ value	8.99809 (rank : 409)	NC score	0.026165 (rank : 395)
Query Neighborhood Hits	414	Target Neighborhood Hits	90	Shared Neighborhood Hits	22
SwissProt Accessions	P48432	Gene names	Sox2, Sox-2
Domain Architecture
Description	Transcription factor SOX-2.

SRY_MOUSE
θ value	8.99809 (rank : 410)	NC score	0.025979 (rank : 397)
Query Neighborhood Hits	414	Target Neighborhood Hits	139	Shared Neighborhood Hits	25
SwissProt Accessions	Q05738	Gene names	Sry, Tdf, Tdy
Domain Architecture
Description	Sex-determining region Y protein (Testis-determining factor).

WDR67_MOUSE
θ value	8.99809 (rank : 411)	NC score	0.252479 (rank : 280)
Query Neighborhood Hits	414	Target Neighborhood Hits	476	Shared Neighborhood Hits	132
SwissProt Accessions	Q6NXY1, Q3TBW4, Q3U4F6, Q5KSA3, Q810J7, Q8C3Y2	Gene names	Wdr67
Domain Architecture	No domain graphic available
Description	WD repeat protein 67 (Protein 4-B-3).

WDR74_MOUSE
θ value	8.99809 (rank : 412)	NC score	0.132931 (rank : 325)
Query Neighborhood Hits	414	Target Neighborhood Hits	70	Shared Neighborhood Hits	53
SwissProt Accessions	Q8VCG3	Gene names	Wdr74
Domain Architecture	No domain graphic available
Description	WD repeat protein 74.

WDTC1_HUMAN
θ value	8.99809 (rank : 413)	NC score	0.419561 (rank : 211)
Query Neighborhood Hits	414	Target Neighborhood Hits	299	Shared Neighborhood Hits	211
SwissProt Accessions	Q8N5D0, Q9NV87, Q9UPW4	Gene names	WDTC1, KIAA1037
Domain Architecture
Description	WD and tetratricopeptide repeats protein 1.

WDTC1_MOUSE
θ value	8.99809 (rank : 414)	NC score	0.418030 (rank : 212)
Query Neighborhood Hits	414	Target Neighborhood Hits	298	Shared Neighborhood Hits	211
SwissProt Accessions	Q80ZK9	Gene names	Wdtc1
Domain Architecture
Description	WD and tetratricopeptide repeats protein 1.

BRWD2_HUMAN
θ value	θ > 10 (rank : 415)	NC score	0.148581 (rank : 314)
Query Neighborhood Hits	414	Target Neighborhood Hits	94	Shared Neighborhood Hits	75
SwissProt Accessions	Q9BZH6, Q5VWA1	Gene names	BRWD2, WDR11
Domain Architecture
Description	Bromodomain and WD repeat domain-containing protein 2 (WD repeat protein 11).

COR2B_HUMAN
θ value	θ > 10 (rank : 416)	NC score	0.388830 (rank : 229)
Query Neighborhood Hits	414	Target Neighborhood Hits	233	Shared Neighborhood Hits	194
SwissProt Accessions	Q9UQ03, O94767, Q8TAN1	Gene names	CORO2B, KIAA0925
Domain Architecture
Description	Coronin-2B (Coronin-like protein C) (ClipinC) (Protein FC96).

DC1I1_HUMAN
θ value	θ > 10 (rank : 417)	NC score	0.164795 (rank : 304)
Query Neighborhood Hits	414	Target Neighborhood Hits	183	Shared Neighborhood Hits	104
SwissProt Accessions	O14576, Q9Y2X1	Gene names	DYNC1I1, DNCI1, DNCIC1
Domain Architecture
Description	Cytoplasmic dynein 1 intermediate chain 1 (Dynein intermediate chain 1, cytosolic) (DH IC-1) (Cytoplasmic dynein intermediate chain 1).

DC1I1_MOUSE
θ value	θ > 10 (rank : 418)	NC score	0.159361 (rank : 306)
Query Neighborhood Hits	414	Target Neighborhood Hits	206	Shared Neighborhood Hits	108
SwissProt Accessions	O88485, O88486	Gene names	Dync1i1, Dnci1, Dncic1
Domain Architecture
Description	Cytoplasmic dynein 1 intermediate chain 1 (Dynein intermediate chain 1, cytosolic) (DH IC-1) (Cytoplasmic dynein intermediate chain 1).

DNAI1_HUMAN
θ value	θ > 10 (rank : 419)	NC score	0.210678 (rank : 292)
Query Neighborhood Hits	414	Target Neighborhood Hits	148	Shared Neighborhood Hits	110
SwissProt Accessions	Q9UI46, Q9UEZ8	Gene names	DNAI1
Domain Architecture
Description	Dynein intermediate chain 1, axonemal (Axonemal dynein intermediate chain 1).

DNAI2_HUMAN
θ value	θ > 10 (rank : 420)	NC score	0.192263 (rank : 301)
Query Neighborhood Hits	414	Target Neighborhood Hits	156	Shared Neighborhood Hits	101
SwissProt Accessions	Q9GZS0, Q9H179, Q9NT53	Gene names	DNAI2
Domain Architecture
Description	Dynein intermediate chain 2, axonemal (Axonemal dynein intermediate chain 2).

FBXW4_HUMAN
θ value	θ > 10 (rank : 421)	NC score	0.355592 (rank : 250)
Query Neighborhood Hits	414	Target Neighborhood Hits	209	Shared Neighborhood Hits	151
SwissProt Accessions	P57775, Q5SVS1, Q96IM6	Gene names	FBXW4, FBW4, SHFM3
Domain Architecture
Description	F-box/WD repeat protein 4 (F-box and WD-40 domain protein 4) (Dactylin).

FBXW4_MOUSE
θ value	θ > 10 (rank : 422)	NC score	0.374874 (rank : 237)
Query Neighborhood Hits	414	Target Neighborhood Hits	205	Shared Neighborhood Hits	154
SwissProt Accessions	Q9JMJ2, Q9QXW3	Gene names	Fbxw4, Fbw4
Domain Architecture
Description	F-box/WD repeat protein 4 (F-box and WD-40 domain protein 4) (Hagoromo protein).

FBXW8_HUMAN
θ value	θ > 10 (rank : 423)	NC score	0.234240 (rank : 285)
Query Neighborhood Hits	414	Target Neighborhood Hits	192	Shared Neighborhood Hits	115
SwissProt Accessions	Q8N3Y1, Q9UK95	Gene names	FBXW8, FBW6, FBW8, FBX29, FBXO29, FBXW6
Domain Architecture
Description	F-box/WD repeat protein 8 (F-box and WD-40 domain protein 8) (F-box only protein 29).

FBXW8_MOUSE
θ value	θ > 10 (rank : 424)	NC score	0.202791 (rank : 298)
Query Neighborhood Hits	414	Target Neighborhood Hits	162	Shared Neighborhood Hits	90
SwissProt Accessions	Q8BIA4, Q8BI62, Q8BI75, Q8BI76, Q8CID8, Q921Z1	Gene names	Fbxw8
Domain Architecture
Description	F-box/WD repeat protein 8 (F-box and WD-40 domain protein 8).

FBXW9_HUMAN
θ value	θ > 10 (rank : 425)	NC score	0.432649 (rank : 207)
Query Neighborhood Hits	414	Target Neighborhood Hits	184	Shared Neighborhood Hits	145
SwissProt Accessions	Q5XUX1, Q9BT89	Gene names	FBXW9, FBW9
Domain Architecture	No domain graphic available
Description	F-box/WD repeat protein 9 (F-box and WD-40 domain protein 9).

GNB1L_HUMAN
θ value	θ > 10 (rank : 426)	NC score	0.480780 (rank : 187)
Query Neighborhood Hits	414	Target Neighborhood Hits	221	Shared Neighborhood Hits	181
SwissProt Accessions	Q9BYB4, Q9H2S2, Q9H4M4	Gene names	GNB1L, GY2, KIAA1645, WDR14
Domain Architecture
Description	Guanine nucleotide-binding protein subunit beta-like protein 1 (G protein subunit beta-like protein 1) (WD40 repeat-containing protein deleted in VCFS) (Protein WDVCF) (DGCRK3).

KI21A_HUMAN
θ value	θ > 10 (rank : 427)	NC score	0.236695 (rank : 284)
Query Neighborhood Hits	414	Target Neighborhood Hits	1543	Shared Neighborhood Hits	260
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

KI21A_MOUSE
θ value	θ > 10 (rank : 428)	NC score	0.233367 (rank : 286)
Query Neighborhood Hits	414	Target Neighborhood Hits	1317	Shared Neighborhood Hits	241
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

LRBA_HUMAN
θ value	θ > 10 (rank : 429)	NC score	0.144451 (rank : 317)
Query Neighborhood Hits	414	Target Neighborhood Hits	196	Shared Neighborhood Hits	95
SwissProt Accessions	P50851, Q9H2U3, Q9H2U4	Gene names	LRBA, BGL, CDC4L, LBA
Domain Architecture
Description	Lipopolysaccharide-responsive and beige-like anchor protein (CDC4-like protein) (Beige-like protein).

NBEAL_HUMAN
θ value	θ > 10 (rank : 430)	NC score	0.231639 (rank : 287)
Query Neighborhood Hits	414	Target Neighborhood Hits	200	Shared Neighborhood Hits	148
SwissProt Accessions	Q6ZS30, Q6Y876, Q6ZQY5, Q96Q30	Gene names	NBEAL1, ALS2CR17
Domain Architecture	No domain graphic available
Description	Neurobeachin-like 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein).

NBEA_HUMAN
θ value	θ > 10 (rank : 431)	NC score	0.146623 (rank : 315)
Query Neighborhood Hits	414	Target Neighborhood Hits	186	Shared Neighborhood Hits	104
SwissProt Accessions	Q8NFP9, Q9HCM8, Q9NSU1, Q9NW98, Q9Y6J1	Gene names	NBEA, BCL8B, KIAA1544, LYST2
Domain Architecture
Description	Protein neurobeachin (Lysosomal-trafficking regulator 2) (Protein BCL8B).

NBEA_MOUSE
θ value	θ > 10 (rank : 432)	NC score	0.145985 (rank : 316)
Query Neighborhood Hits	414	Target Neighborhood Hits	225	Shared Neighborhood Hits	106
SwissProt Accessions	Q9EPN1, Q8C931, Q9EPM9, Q9EPN0, Q9WVM9	Gene names	Nbea, Lyst2
Domain Architecture
Description	Protein neurobeachin (Lysosomal-trafficking regulator 2).

NIPBL_HUMAN
θ value	θ > 10 (rank : 433)	NC score	0.060086 (rank : 355)
Query Neighborhood Hits	414	Target Neighborhood Hits	1311	Shared Neighborhood Hits	99
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

NPBL_MOUSE
θ value	θ > 10 (rank : 434)	NC score	0.050529 (rank : 360)
Query Neighborhood Hits	414	Target Neighborhood Hits	1041	Shared Neighborhood Hits	85
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

NUP43_HUMAN
θ value	θ > 10 (rank : 435)	NC score	0.318349 (rank : 255)
Query Neighborhood Hits	414	Target Neighborhood Hits	198	Shared Neighborhood Hits	157
SwissProt Accessions	Q8NFH3, Q9H8S0	Gene names	NUP43
Domain Architecture
Description	Nucleoporin Nup43 (p42).

NUP43_MOUSE
θ value	θ > 10 (rank : 436)	NC score	0.318269 (rank : 256)
Query Neighborhood Hits	414	Target Neighborhood Hits	193	Shared Neighborhood Hits	151
SwissProt Accessions	P59235	Gene names	Nup43
Domain Architecture
Description	Nucleoporin Nup43.

PI3R4_HUMAN
θ value	θ > 10 (rank : 437)	NC score	0.156319 (rank : 307)
Query Neighborhood Hits	414	Target Neighborhood Hits	534	Shared Neighborhood Hits	135
SwissProt Accessions	Q99570	Gene names	PIK3R4
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 4 (EC 2.7.11.1) (PI3- kinase regulatory subunit 4) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein).

PI3R4_MOUSE
θ value	θ > 10 (rank : 438)	NC score	0.140775 (rank : 321)
Query Neighborhood Hits	414	Target Neighborhood Hits	535	Shared Neighborhood Hits	129
SwissProt Accessions	Q8VD65, Q56A65, Q8C948, Q8C9D7, Q9CVC5	Gene names	Pik3r4
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 4 (EC 2.7.11.1) (PI3- kinase regulatory subunit 4).

PPWD1_HUMAN
θ value	θ > 10 (rank : 439)	NC score	0.136534 (rank : 323)
Query Neighborhood Hits	414	Target Neighborhood Hits	136	Shared Neighborhood Hits	98
SwissProt Accessions	Q96BP3, Q15002, Q7KZ89	Gene names	PPWD1, KIAA0073
Domain Architecture	No domain graphic available
Description	Peptidylprolyl isomerase domain and WD repeat-containing protein 1 (EC 5.2.1.8).

PPWD1_MOUSE
θ value	θ > 10 (rank : 440)	NC score	0.130515 (rank : 327)
Query Neighborhood Hits	414	Target Neighborhood Hits	139	Shared Neighborhood Hits	95
SwissProt Accessions	Q8CEC6	Gene names	Ppwd1
Domain Architecture	No domain graphic available
Description	Peptidylprolyl isomerase domain and WD repeat-containing protein 1 (EC 5.2.1.8).

PREB_HUMAN
θ value	θ > 10 (rank : 441)	NC score	0.330657 (rank : 254)
Query Neighborhood Hits	414	Target Neighborhood Hits	163	Shared Neighborhood Hits	139
SwissProt Accessions	Q9HCU5, Q9UH94	Gene names	PREB, SEC12
Domain Architecture
Description	Prolactin regulatory element-binding protein (Mammalian guanine nucleotide exchange factor mSec12).

PREB_MOUSE
θ value	θ > 10 (rank : 442)	NC score	0.298909 (rank : 262)
Query Neighborhood Hits	414	Target Neighborhood Hits	156	Shared Neighborhood Hits	132
SwissProt Accessions	Q9WUQ2, Q9QZ99	Gene names	Preb, Sec12
Domain Architecture
Description	Prolactin regulatory element-binding protein (Mammalian guanine nucleotide exchange factor mSec12).

RBBP7_HUMAN
θ value	θ > 10 (rank : 443)	NC score	0.501581 (rank : 178)
Query Neighborhood Hits	414	Target Neighborhood Hits	285	Shared Neighborhood Hits	230
SwissProt Accessions	Q16576	Gene names	RBBP7, RBAP46
Domain Architecture
Description	Histone-binding protein RBBP7 (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46) (Histone acetyltransferase type B subunit 2) (Nucleosome remodeling factor subunit RBAP46).

RBBP7_MOUSE
θ value	θ > 10 (rank : 444)	NC score	0.501129 (rank : 179)
Query Neighborhood Hits	414	Target Neighborhood Hits	285	Shared Neighborhood Hits	230
SwissProt Accessions	Q60973, Q3UX20	Gene names	Rbbp7, Rbap46
Domain Architecture
Description	Histone-binding protein RBBP7 (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46) (Histone acetyltransferase type B subunit 2) (Nucleosome remodeling factor subunit RBAP46).

SCAP_HUMAN
θ value	θ > 10 (rank : 445)	NC score	0.450408 (rank : 202)
Query Neighborhood Hits	414	Target Neighborhood Hits	368	Shared Neighborhood Hits	183
SwissProt Accessions	Q12770, Q8N2E0, Q8WUA1	Gene names	SCAP, KIAA0199
Domain Architecture
Description	Sterol regulatory element-binding protein cleavage-activating protein (SREBP cleavage-activating protein) (SCAP).

STXB5_HUMAN
θ value	θ > 10 (rank : 446)	NC score	0.133227 (rank : 324)
Query Neighborhood Hits	414	Target Neighborhood Hits	167	Shared Neighborhood Hits	116
SwissProt Accessions	Q5T5C0, Q5T5C1, Q5T5C2, Q8NBG8, Q96NG9	Gene names	STXBP5, LLGL3
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 5 (Tomosyn-1) (Lethal(2) giant larvae protein homolog 3).

STXB5_MOUSE
θ value	θ > 10 (rank : 447)	NC score	0.123616 (rank : 329)
Query Neighborhood Hits	414	Target Neighborhood Hits	161	Shared Neighborhood Hits	110
SwissProt Accessions	Q8K400, Q80TM5, Q8K401, Q9D2F3	Gene names	Stxbp5, Kiaa4253, Llgl3
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 5 (Tomosyn-1) (Lethal(2) giant larvae protein homolog 3).

THOC6_MOUSE
θ value	θ > 10 (rank : 448)	NC score	0.397893 (rank : 219)
Query Neighborhood Hits	414	Target Neighborhood Hits	199	Shared Neighborhood Hits	165
SwissProt Accessions	Q5U4D9	Gene names	Thoc6, Wdr58
Domain Architecture	No domain graphic available
Description	THO complex subunit 6 homolog (WD repeat protein 58).

TLE1_HUMAN
θ value	θ > 10 (rank : 449)	NC score	0.364226 (rank : 248)
Query Neighborhood Hits	414	Target Neighborhood Hits	485	Shared Neighborhood Hits	215
SwissProt Accessions	Q04724, Q5T3G4, Q969V9	Gene names	TLE1
Domain Architecture
Description	Transducin-like enhancer protein 1 (ESG1) (E(Sp1) homolog).

TLE1_MOUSE
θ value	θ > 10 (rank : 450)	NC score	0.364327 (rank : 247)
Query Neighborhood Hits	414	Target Neighborhood Hits	491	Shared Neighborhood Hits	217
SwissProt Accessions	Q62440	Gene names	Tle1, Grg1
Domain Architecture
Description	Transducin-like enhancer protein 1 (Groucho-related protein 1) (Grg- 1).

TLE2_HUMAN
θ value	θ > 10 (rank : 451)	NC score	0.372058 (rank : 240)
Query Neighborhood Hits	414	Target Neighborhood Hits	321	Shared Neighborhood Hits	215
SwissProt Accessions	Q04725, Q8WVY0, Q9Y6S0	Gene names	TLE2
Domain Architecture
Description	Transducin-like enhancer protein 2 (ESG2).

TLE2_MOUSE
θ value	θ > 10 (rank : 452)	NC score	0.371654 (rank : 241)
Query Neighborhood Hits	414	Target Neighborhood Hits	294	Shared Neighborhood Hits	213
SwissProt Accessions	Q9WVB2	Gene names	Tle2, Grg2
Domain Architecture
Description	Transducin-like enhancer protein 2.

TLE3_HUMAN
θ value	θ > 10 (rank : 453)	NC score	0.370537 (rank : 243)
Query Neighborhood Hits	414	Target Neighborhood Hits	385	Shared Neighborhood Hits	216
SwissProt Accessions	Q04726, Q8IVV6, Q8WVR2, Q9HCM5	Gene names	TLE3, KIAA1547
Domain Architecture
Description	Transducin-like enhancer protein 3 (ESG3).

TLE3_MOUSE
θ value	θ > 10 (rank : 454)	NC score	0.372826 (rank : 239)
Query Neighborhood Hits	414	Target Neighborhood Hits	378	Shared Neighborhood Hits	216
SwissProt Accessions	Q08122, Q923A4	Gene names	Tle3, Esg
Domain Architecture
Description	Transducin-like enhancer protein 3 (ESG) (Grg-3).

TLE4_HUMAN
θ value	θ > 10 (rank : 455)	NC score	0.375926 (rank : 236)
Query Neighborhood Hits	414	Target Neighborhood Hits	477	Shared Neighborhood Hits	222
SwissProt Accessions	Q04727, Q5T1Y2, Q9BZ07, Q9BZ08, Q9BZ09, Q9NSL3, Q9ULF9	Gene names	TLE4, KIAA1261
Domain Architecture
Description	Transducin-like enhancer protein 4.

TLE4_MOUSE
θ value	θ > 10 (rank : 456)	NC score	0.376019 (rank : 235)
Query Neighborhood Hits	414	Target Neighborhood Hits	482	Shared Neighborhood Hits	223
SwissProt Accessions	Q62441, Q9JKQ9	Gene names	Tle4, Grg4
Domain Architecture
Description	Transducin-like enhancer protein 4 (Groucho-related protein 4) (Grg- 4).

TLE6_HUMAN
θ value	θ > 10 (rank : 457)	NC score	0.149265 (rank : 313)
Query Neighborhood Hits	414	Target Neighborhood Hits	120	Shared Neighborhood Hits	80
SwissProt Accessions	Q9H808	Gene names	TLE6
Domain Architecture	No domain graphic available
Description	Transducin-like enhancer protein 6.

TLE6_MOUSE
θ value	θ > 10 (rank : 458)	NC score	0.257725 (rank : 278)
Query Neighborhood Hits	414	Target Neighborhood Hits	178	Shared Neighborhood Hits	129
SwissProt Accessions	Q9WVB3	Gene names	Tle6, Grg6
Domain Architecture
Description	Transducin-like enhancer protein 6 (Groucho-related protein 6).

TSCC1_MOUSE
θ value	θ > 10 (rank : 459)	NC score	0.286870 (rank : 269)
Query Neighborhood Hits	414	Target Neighborhood Hits	160	Shared Neighborhood Hits	128
SwissProt Accessions	Q8K0G5	Gene names	Tssc1
Domain Architecture	No domain graphic available
Description	Protein TSSC1.

TSSC1_HUMAN
θ value	θ > 10 (rank : 460)	NC score	0.276748 (rank : 272)
Query Neighborhood Hits	414	Target Neighborhood Hits	157	Shared Neighborhood Hits	130
SwissProt Accessions	Q53HC9, O43179, Q53S19, Q53SG2	Gene names	TSSC1
Domain Architecture	No domain graphic available
Description	Protein TSSC1 (Tumor-suppressing subchromosomal transferable fragment candidate gene 1 protein) (Tumor-suppressing STF cDNA 1 protein).

TULP4_HUMAN
θ value	θ > 10 (rank : 461)	NC score	0.095824 (rank : 340)
Query Neighborhood Hits	414	Target Neighborhood Hits	426	Shared Neighborhood Hits	90
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

TULP4_MOUSE
θ value	θ > 10 (rank : 462)	NC score	0.104598 (rank : 333)
Query Neighborhood Hits	414	Target Neighborhood Hits	247	Shared Neighborhood Hits	86
SwissProt Accessions	Q9JIL5, Q8CA75, Q922C2	Gene names	Tulp4, Tusp
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

UTP18_HUMAN
θ value	θ > 10 (rank : 463)	NC score	0.301786 (rank : 261)
Query Neighborhood Hits	414	Target Neighborhood Hits	139	Shared Neighborhood Hits	109
SwissProt Accessions	Q9Y5J1, Q9H4N6	Gene names	UTP18, WDR50
Domain Architecture
Description	U3 small nucleolar RNA-associated protein 18 homolog (WD repeat protein 50).

UTP18_MOUSE
θ value	θ > 10 (rank : 464)	NC score	0.242083 (rank : 283)
Query Neighborhood Hits	414	Target Neighborhood Hits	139	Shared Neighborhood Hits	98
SwissProt Accessions	Q5SSI6	Gene names	Utp18, Wdr50
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 18 homolog (WD repeat protein 50).

WD21A_HUMAN
θ value	θ > 10 (rank : 465)	NC score	0.271755 (rank : 274)
Query Neighborhood Hits	414	Target Neighborhood Hits	136	Shared Neighborhood Hits	119
SwissProt Accessions	Q8WV16, Q86U31, Q96K22, Q9Y4P5	Gene names	WDR21A, WDR21
Domain Architecture
Description	WD repeat protein 21A.

WDFY1_HUMAN
θ value	θ > 10 (rank : 466)	NC score	0.446045 (rank : 205)
Query Neighborhood Hits	414	Target Neighborhood Hits	305	Shared Neighborhood Hits	218
SwissProt Accessions	Q8IWB7, Q9H9D5, Q9P2B3	Gene names	WDFY1, KIAA1435, WDF1, ZFYVE17
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 1 (WD40- and FYVE domain- containing protein 1) (Phosphoinositide-binding protein 1) (FENS-1) (Zinc finger FYVE domain-containing protein 17).

WDFY3_HUMAN
θ value	θ > 10 (rank : 467)	NC score	0.246446 (rank : 282)
Query Neighborhood Hits	414	Target Neighborhood Hits	348	Shared Neighborhood Hits	174
SwissProt Accessions	Q8IZQ1, Q4W5K5, Q6P0Q5, Q8N1T2, Q96BS7, Q96N85, Q9Y2J7	Gene names	WDFY3, KIAA0993
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy).

WDFY3_MOUSE
θ value	θ > 10 (rank : 468)	NC score	0.249026 (rank : 281)
Query Neighborhood Hits	414	Target Neighborhood Hits	332	Shared Neighborhood Hits	173
SwissProt Accessions	Q6VNB8, Q8C8H7	Gene names	Wdfy3
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Beach domain, WD repeat and FYVE domain-containing protein 1) (BWF1).

WDR41_HUMAN
θ value	θ > 10 (rank : 469)	NC score	0.370385 (rank : 244)
Query Neighborhood Hits	414	Target Neighborhood Hits	208	Shared Neighborhood Hits	177
SwissProt Accessions	Q9HAD4, Q7Z792, Q8IWG3, Q8IXA9, Q8NDA7, Q9NV62	Gene names	WDR41
Domain Architecture	No domain graphic available
Description	WD repeat protein 41.

WDR41_MOUSE
θ value	θ > 10 (rank : 470)	NC score	0.398215 (rank : 218)
Query Neighborhood Hits	414	Target Neighborhood Hits	209	Shared Neighborhood Hits	172
SwissProt Accessions	Q3UDP0, Q8C4F1, Q8C8K5	Gene names	Wdr41
Domain Architecture	No domain graphic available
Description	WD repeat protein 41.

WDR43_HUMAN
θ value	θ > 10 (rank : 471)	NC score	0.486797 (rank : 186)
Query Neighborhood Hits	414	Target Neighborhood Hits	269	Shared Neighborhood Hits	169
SwissProt Accessions	Q15061, Q15395, Q92577	Gene names	WDR43, KIAA0007
Domain Architecture	No domain graphic available
Description	WD repeat protein 43.

WDR46_HUMAN
θ value	θ > 10 (rank : 472)	NC score	0.226956 (rank : 288)
Query Neighborhood Hits	414	Target Neighborhood Hits	147	Shared Neighborhood Hits	102
SwissProt Accessions	O15213, Q5STK5	Gene names	WDR46, BING4, C6orf11
Domain Architecture
Description	WD repeat protein 46 (WD repeat protein BING4).

WDR4_HUMAN
θ value	θ > 10 (rank : 473)	NC score	0.276362 (rank : 273)
Query Neighborhood Hits	414	Target Neighborhood Hits	145	Shared Neighborhood Hits	122
SwissProt Accessions	P57081, Q9HCR3	Gene names	WDR4
Domain Architecture
Description	WD repeat protein 4.

WDR4_MOUSE
θ value	θ > 10 (rank : 474)	NC score	0.279684 (rank : 271)
Query Neighborhood Hits	414	Target Neighborhood Hits	136	Shared Neighborhood Hits	119
SwissProt Accessions	Q9EP82	Gene names	Wdr4
Domain Architecture
Description	WD repeat protein 4.

WDR54_HUMAN
θ value	θ > 10 (rank : 475)	NC score	0.081798 (rank : 344)
Query Neighborhood Hits	414	Target Neighborhood Hits	70	Shared Neighborhood Hits	57
SwissProt Accessions	Q9H977, Q53H85, Q86V45	Gene names	WDR54
Domain Architecture	No domain graphic available
Description	WD repeat protein 54.

WDR54_MOUSE
θ value	θ > 10 (rank : 476)	NC score	0.128636 (rank : 328)
Query Neighborhood Hits	414	Target Neighborhood Hits	96	Shared Neighborhood Hits	78
SwissProt Accessions	Q9R0D8, Q3U4A4	Gene names	Wdr54, D3Mm3e
Domain Architecture	No domain graphic available
Description	WD repeat protein 54.

WDR68_HUMAN
θ value	θ > 10 (rank : 477)	NC score	0.205397 (rank : 296)
Query Neighborhood Hits	414	Target Neighborhood Hits	121	Shared Neighborhood Hits	107
SwissProt Accessions	P61962, O15491, Q9DAE4	Gene names	WDR68, HAN11
Domain Architecture
Description	WD repeat protein 68 (WD repeat protein An11 homolog).

WDR68_MOUSE
θ value	θ > 10 (rank : 478)	NC score	0.205397 (rank : 297)
Query Neighborhood Hits	414	Target Neighborhood Hits	121	Shared Neighborhood Hits	107
SwissProt Accessions	P61963, O15491, Q3TMV9, Q9DAE4	Gene names	Wdr68, Han11
Domain Architecture
Description	WD repeat protein 68 (WD repeat protein An11 homolog).

WDR6_HUMAN
θ value	θ > 10 (rank : 479)	NC score	0.394392 (rank : 224)
Query Neighborhood Hits	414	Target Neighborhood Hits	193	Shared Neighborhood Hits	155
SwissProt Accessions	Q9NNW5, Q9UF63	Gene names	WDR6
Domain Architecture
Description	WD repeat protein 6.

WDR72_HUMAN
θ value	θ > 10 (rank : 480)	NC score	0.297116 (rank : 263)
Query Neighborhood Hits	414	Target Neighborhood Hits	167	Shared Neighborhood Hits	135
SwissProt Accessions	Q3MJ13, Q7Z3I3, Q8N8X2	Gene names	WDR72
Domain Architecture	No domain graphic available
Description	WD repeat protein 72.

WDR74_HUMAN
θ value	θ > 10 (rank : 481)	NC score	0.161985 (rank : 305)
Query Neighborhood Hits	414	Target Neighborhood Hits	94	Shared Neighborhood Hits	68
SwissProt Accessions	Q6RFH5, Q9BRC9, Q9H6X8, Q9NVY2	Gene names	WDR74, NSA1
Domain Architecture	No domain graphic available
Description	WD repeat protein 74 (NOP seven-associated protein 1).

WDR76_HUMAN
θ value	θ > 10 (rank : 482)	NC score	0.079215 (rank : 345)
Query Neighborhood Hits	414	Target Neighborhood Hits	73	Shared Neighborhood Hits	51
SwissProt Accessions	Q9H967	Gene names	WDR76
Domain Architecture	No domain graphic available
Description	WD repeat protein 76.

WDR81_HUMAN
θ value	θ > 10 (rank : 483)	NC score	0.288038 (rank : 268)
Query Neighborhood Hits	414	Target Neighborhood Hits	205	Shared Neighborhood Hits	151
SwissProt Accessions	Q562E7, Q24JP6, Q8N277, Q8N3F3	Gene names	WDR81
Domain Architecture	No domain graphic available
Description	WD repeat protein 81.

WDR81_MOUSE
θ value	θ > 10 (rank : 484)	NC score	0.316617 (rank : 258)
Query Neighborhood Hits	414	Target Neighborhood Hits	228	Shared Neighborhood Hits	159
SwissProt Accessions	Q5ND34, Q3TA90, Q3TUS9, Q6KAR1	Gene names	Wdr81
Domain Architecture	No domain graphic available
Description	WD repeat protein 81.

WDR85_HUMAN
θ value	θ > 10 (rank : 485)	NC score	0.205940 (rank : 295)
Query Neighborhood Hits	414	Target Neighborhood Hits	134	Shared Neighborhood Hits	116
SwissProt Accessions	Q9BTV6, Q96AB7	Gene names	WDR85, C9orf112
Domain Architecture	No domain graphic available
Description	WD repeat protein 85.

WDR85_MOUSE
θ value	θ > 10 (rank : 486)	NC score	0.143420 (rank : 318)
Query Neighborhood Hits	414	Target Neighborhood Hits	108	Shared Neighborhood Hits	87
SwissProt Accessions	Q9CYU6, Q5RJV7, Q8BIT9	Gene names	Wdr85
Domain Architecture	No domain graphic available
Description	WD repeat protein 85.

WDR8_HUMAN
θ value	θ > 10 (rank : 487)	NC score	0.141240 (rank : 320)
Query Neighborhood Hits	414	Target Neighborhood Hits	69	Shared Neighborhood Hits	62
SwissProt Accessions	Q9P2S5, Q5T0D6, Q9BUH7, Q9NTK7, Q9NX56	Gene names	WDR8
Domain Architecture
Description	WD repeat protein 8.

WDR8_MOUSE
θ value	θ > 10 (rank : 488)	NC score	0.141697 (rank : 319)
Query Neighborhood Hits	414	Target Neighborhood Hits	71	Shared Neighborhood Hits	64
SwissProt Accessions	Q9JM98	Gene names	Wdr8, Dd57
Domain Architecture
Description	WD repeat protein 8.

WIPI1_HUMAN
θ value	θ > 10 (rank : 489)	NC score	0.092120 (rank : 342)
Query Neighborhood Hits	414	Target Neighborhood Hits	60	Shared Neighborhood Hits	44
SwissProt Accessions	Q5MNZ9, Q8IXM5, Q9NWF8	Gene names	WIPI1, WIPI49
Domain Architecture	No domain graphic available
Description	WD repeat domain phosphoinositide-interacting protein 1 (WIPI-1) (WD40 repeat protein interacting with phosphoinositides of 49 kDa) (WIPI 49 kDa) (Atg18 protein homolog).

WIPI1_MOUSE
θ value	θ > 10 (rank : 490)	NC score	0.106688 (rank : 332)
Query Neighborhood Hits	414	Target Neighborhood Hits	67	Shared Neighborhood Hits	49
SwissProt Accessions	Q8R3E3, Q8BGE1, Q8R1A9, Q8R1C7	Gene names	Wipi1, D11Ertd498e
Domain Architecture	No domain graphic available
Description	WD repeat domain phosphoinositide-interacting protein 1 (WIPI-1) (WD40 repeat protein interacting with phosphoinositides of 49 kDa) (WIPI 49 kDa).

WIPI3_HUMAN
θ value	θ > 10 (rank : 491)	NC score	0.071162 (rank : 347)
Query Neighborhood Hits	414	Target Neighborhood Hits	53	Shared Neighborhood Hits	38
SwissProt Accessions	Q5MNZ6, O95328, Q6IBN2	Gene names	WDR45L, WIPI3
Domain Architecture	No domain graphic available
Description	WD repeat domain phosphoinositide-interacting protein 3 (WIPI-3) (WD repeat protein 45-like) (WDR45-like protein) (WIPI49-like protein).

WIPI3_MOUSE
θ value	θ > 10 (rank : 492)	NC score	0.071578 (rank : 346)
Query Neighborhood Hits	414	Target Neighborhood Hits	51	Shared Neighborhood Hits	39
SwissProt Accessions	Q9CR39, Q3U924	Gene names	Wdr45l, Wipi3
Domain Architecture	No domain graphic available
Description	WD repeat domain phosphoinositide-interacting protein 3 (WIPI-3) (WD repeat protein 45-like) (WDR45-like protein).

WIPI4_MOUSE
θ value	θ > 10 (rank : 493)	NC score	0.050169 (rank : 361)
Query Neighborhood Hits	414	Target Neighborhood Hits	47	Shared Neighborhood Hits	33
SwissProt Accessions	Q91VM3, Q9CVF7, Q9JIG9	Gene names	Wdr45, DXImx38e, Wdrx1, Wipi4
Domain Architecture	No domain graphic available
Description	WD repeat domain phosphoinositide-interacting protein 4 (WIPI-4) (WD repeat protein 45) (WD repeat domain X-linked 1).

Hits sorted by NC score

WDHD1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	414	Target Neighborhood Hits	414	Shared Neighborhood Hits	414
SwissProt Accessions	P59328, Q6P408	Gene names	Wdhd1, And1
Domain Architecture	No domain graphic available
Description	WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA- binding protein 1) (And-1).

WDHD1_HUMAN
NC score	0.961940 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	414	Target Neighborhood Hits	342	Shared Neighborhood Hits	259
SwissProt Accessions	O75717	Gene names	WDHD1, AND1
Domain Architecture
Description	WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA- binding protein 1) (And-1).

WDR5_HUMAN
NC score	0.719423 (rank : 3)	θ value	1.29331e-14 (rank : 3)
Query Neighborhood Hits	414	Target Neighborhood Hits	341	Shared Neighborhood Hits	255
SwissProt Accessions	P61964, Q91VA5, Q9NWX7, Q9UGP9	Gene names	WDR5, BIG3
Domain Architecture
Description	WD repeat protein 5 (BMP2-induced 3-kb gene protein).

WDR5_MOUSE
NC score	0.719423 (rank : 4)	θ value	1.29331e-14 (rank : 4)
Query Neighborhood Hits	414	Target Neighborhood Hits	341	Shared Neighborhood Hits	255
SwissProt Accessions	P61965, Q91VA5, Q922C9, Q9NWX7, Q9UGP9	Gene names	Wdr5, Big, Big3
Domain Architecture
Description	WD repeat protein 5 (BMP2-induced 3-kb gene protein) (WD repeat protein BIG-3).

WDR39_HUMAN
NC score	0.712251 (rank : 5)	θ value	2.28291e-11 (rank : 6)
Query Neighborhood Hits	414	Target Neighborhood Hits	296	Shared Neighborhood Hits	239
SwissProt Accessions	O76071	Gene names	WDR39, CIAO1
Domain Architecture
Description	WD repeat protein 39 (Ciao 1 protein).

WD51B_HUMAN
NC score	0.704941 (rank : 6)	θ value	2.13673e-09 (rank : 19)
Query Neighborhood Hits	414	Target Neighborhood Hits	335	Shared Neighborhood Hits	255
SwissProt Accessions	Q8TC44	Gene names	WDR51B
Domain Architecture	No domain graphic available
Description	WD repeat protein 51B.

WDR57_MOUSE
NC score	0.704268 (rank : 7)	θ value	6.64225e-11 (rank : 10)
Query Neighborhood Hits	414	Target Neighborhood Hits	323	Shared Neighborhood Hits	250
SwissProt Accessions	Q6PE01, Q3TEJ3, Q9DCX3	Gene names	Wdr57
Domain Architecture	No domain graphic available
Description	WD repeat protein 57.

SPG16_MOUSE
NC score	0.704181 (rank : 8)	θ value	1.80886e-08 (rank : 27)
Query Neighborhood Hits	414	Target Neighborhood Hits	377	Shared Neighborhood Hits	253
SwissProt Accessions	Q8K450, Q8C450, Q9CPU8, Q9D522	Gene names	Spag16, Pf20
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 16 protein (PF20 protein homolog).

WDR57_HUMAN
NC score	0.703522 (rank : 9)	θ value	6.64225e-11 (rank : 9)
Query Neighborhood Hits	414	Target Neighborhood Hits	322	Shared Neighborhood Hits	250
SwissProt Accessions	Q96DI7, O75938, O95320	Gene names	WDR57, PRP8BP, SFP38
Domain Architecture	No domain graphic available
Description	WD repeat protein 57 (Prp8-binding protein) (hPRP8BP) (U5 snRNP- specific 40 kDa protein) (38 kDa-splicing factor).

TBL1X_HUMAN
NC score	0.702645 (rank : 10)	θ value	1.25267e-09 (rank : 16)
Query Neighborhood Hits	414	Target Neighborhood Hits	329	Shared Neighborhood Hits	258
SwissProt Accessions	O60907, Q86UY2	Gene names	TBL1X, TBL1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1X (Transducin beta-like 1X protein) (Transducin-beta-like 1, X-linked) (SMAP55).

LIS1_HUMAN
NC score	0.702503 (rank : 11)	θ value	4.0297e-08 (rank : 33)
Query Neighborhood Hits	414	Target Neighborhood Hits	333	Shared Neighborhood Hits	249
SwissProt Accessions	P43034, Q8WZ88, Q8WZ89	Gene names	PAFAH1B1, LIS1, MDCR, PAFAHA
Domain Architecture
Description	Platelet-activating factor acetylhydrolase IB subunit alpha (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1).

LIS1_MOUSE
NC score	0.702450 (rank : 12)	θ value	4.0297e-08 (rank : 34)
Query Neighborhood Hits	414	Target Neighborhood Hits	336	Shared Neighborhood Hits	249
SwissProt Accessions	P63005, O35592, P43035, P81692, Q9R2A6	Gene names	Pafah1b1, Lis-1, Lis1, Pafaha
Domain Architecture	No domain graphic available
Description	Platelet-activating factor acetylhydrolase IB subunit alpha (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1).

TBL1R_MOUSE
NC score	0.702150 (rank : 13)	θ value	9.59137e-10 (rank : 15)
Query Neighborhood Hits	414	Target Neighborhood Hits	329	Shared Neighborhood Hits	260
SwissProt Accessions	Q8BHJ5, Q3UWL6, Q8CBG4, Q8VEG3, Q9EQD4	Gene names	Tbl1xr1, Ira1, Tblr1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1XR1 (Transducin beta-like 1X-related protein 1) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1).

TBL1R_HUMAN
NC score	0.701933 (rank : 14)	θ value	9.59137e-10 (rank : 14)
Query Neighborhood Hits	414	Target Neighborhood Hits	327	Shared Neighborhood Hits	260
SwissProt Accessions	Q9BZK7, Q9H2I1, Q9H9A1	Gene names	TBL1XR1, IRA1, TBLR1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1XR1 (Transducin beta-like 1X-related protein 1) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1).

TBLX_MOUSE
NC score	0.701712 (rank : 15)	θ value	3.64472e-09 (rank : 21)
Query Neighborhood Hits	414	Target Neighborhood Hits	335	Shared Neighborhood Hits	260
SwissProt Accessions	Q9QXE7, Q8BMM0, Q8BYQ4, Q8C0A1	Gene names	Tbl1x, Tbl1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1X (Transducin beta-like 1X protein).

SPG16_HUMAN
NC score	0.701301 (rank : 16)	θ value	1.80886e-08 (rank : 26)
Query Neighborhood Hits	414	Target Neighborhood Hits	361	Shared Neighborhood Hits	248
SwissProt Accessions	Q8N0X2, Q658W1, Q68DB3, Q6I9Z6, Q8N9C7, Q9H601	Gene names	SPAG16, PF20
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 16 protein (PF20 protein homolog).

TBL1Y_HUMAN
NC score	0.700832 (rank : 17)	θ value	2.36244e-08 (rank : 28)
Query Neighborhood Hits	414	Target Neighborhood Hits	331	Shared Neighborhood Hits	258
SwissProt Accessions	Q9BQ87	Gene names	TBL1Y, TBL1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1Y (Transducin beta-like 1Y protein) (Transducin-beta-like 1, Y-linked).

WDR69_HUMAN
NC score	0.699931 (rank : 18)	θ value	8.11959e-09 (rank : 24)
Query Neighborhood Hits	414	Target Neighborhood Hits	324	Shared Neighborhood Hits	248
SwissProt Accessions	Q8N136, Q6ZRY1, Q8N776	Gene names	WDR69
Domain Architecture	No domain graphic available
Description	WD repeat protein 69.

APAF_MOUSE
NC score	0.699325 (rank : 19)	θ value	3.89403e-11 (rank : 8)
Query Neighborhood Hits	414	Target Neighborhood Hits	343	Shared Neighborhood Hits	257
SwissProt Accessions	O88879	Gene names	Apaf1
Domain Architecture
Description	Apoptotic protease-activating factor 1 (Apaf-1).

WD51B_MOUSE
NC score	0.698998 (rank : 20)	θ value	2.36244e-08 (rank : 30)
Query Neighborhood Hits	414	Target Neighborhood Hits	321	Shared Neighborhood Hits	257
SwissProt Accessions	Q8BHD1	Gene names	Wdr51b
Domain Architecture	No domain graphic available
Description	WD repeat protein 51B.

WD51A_HUMAN
NC score	0.698647 (rank : 21)	θ value	2.36244e-08 (rank : 29)
Query Neighborhood Hits	414	Target Neighborhood Hits	337	Shared Neighborhood Hits	252
SwissProt Accessions	Q8NBT0, Q2TAK6, Q96IK6, Q9UFJ8	Gene names	WDR51A
Domain Architecture	No domain graphic available
Description	WD repeat protein 51A.

WD51A_MOUSE
NC score	0.698331 (rank : 22)	θ value	5.26297e-08 (rank : 35)
Query Neighborhood Hits	414	Target Neighborhood Hits	342	Shared Neighborhood Hits	257
SwissProt Accessions	Q8JZX3, Q9CY09	Gene names	Wdr51a
Domain Architecture	No domain graphic available
Description	WD repeat protein 51A.

WDR61_HUMAN
NC score	0.697149 (rank : 23)	θ value	4.45536e-07 (rank : 39)
Query Neighborhood Hits	414	Target Neighborhood Hits	334	Shared Neighborhood Hits	255
SwissProt Accessions	Q9GZS3, Q6IA22, Q7Z4X4	Gene names	WDR61
Domain Architecture	No domain graphic available
Description	WD repeat protein 61 (Meiotic recombination REC14 protein homolog).

TAF5L_MOUSE
NC score	0.697113 (rank : 24)	θ value	1.133e-10 (rank : 11)
Query Neighborhood Hits	414	Target Neighborhood Hits	337	Shared Neighborhood Hits	252
SwissProt Accessions	Q91WQ5, Q8BTL5	Gene names	Taf5l, Paf65b
Domain Architecture
Description	TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65- beta).

WDR61_MOUSE
NC score	0.696974 (rank : 25)	θ value	2.61198e-07 (rank : 36)
Query Neighborhood Hits	414	Target Neighborhood Hits	331	Shared Neighborhood Hits	253
SwissProt Accessions	Q9ERF3, Q3U562, Q9CZP1	Gene names	Wdr61
Domain Architecture	No domain graphic available
Description	WD repeat protein 61 (Meiotic recombination REC14 protein homolog).

TAF5_HUMAN
NC score	0.696016 (rank : 26)	θ value	7.34386e-10 (rank : 13)
Query Neighborhood Hits	414	Target Neighborhood Hits	352	Shared Neighborhood Hits	253
SwissProt Accessions	Q15542, Q86UZ7, Q9Y4K5	Gene names	TAF5, TAF2D
Domain Architecture
Description	Transcription initiation factor TFIID subunit 5 (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100).

TAF5L_HUMAN
NC score	0.694951 (rank : 27)	θ value	7.34386e-10 (rank : 12)
Query Neighborhood Hits	414	Target Neighborhood Hits	330	Shared Neighborhood Hits	253
SwissProt Accessions	O75529, Q8IW31	Gene names	TAF5L, PAF65B
Domain Architecture
Description	TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65- beta).

PRP19_MOUSE
NC score	0.694799 (rank : 28)	θ value	6.21693e-09 (rank : 22)
Query Neighborhood Hits	414	Target Neighborhood Hits	335	Shared Neighborhood Hits	253
SwissProt Accessions	Q99KP6, Q3TP64, Q8BKZ5, Q8BVQ4	Gene names	Prpf19, Prp19, Snev
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor 19 (PRP19/PSO4 homolog) (Nuclear matrix protein 200) (Nuclear matrix protein SNEV).

TAF5_MOUSE
NC score	0.694427 (rank : 29)	θ value	1.63604e-09 (rank : 18)
Query Neighborhood Hits	414	Target Neighborhood Hits	366	Shared Neighborhood Hits	254
SwissProt Accessions	Q8C092, Q8BTR2	Gene names	Taf5
Domain Architecture
Description	Transcription initiation factor TFIID subunit 5 (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100).

PRP19_HUMAN
NC score	0.694373 (rank : 30)	θ value	8.11959e-09 (rank : 23)
Query Neighborhood Hits	414	Target Neighborhood Hits	333	Shared Neighborhood Hits	252
SwissProt Accessions	Q9UMS4	Gene names	PRPF19, NMP200, PRP19
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor 19 (PRP19/PSO4 homolog) (Nuclear matrix protein 200) (hPso4).

APAF_HUMAN
NC score	0.692812 (rank : 31)	θ value	3.64472e-09 (rank : 20)
Query Neighborhood Hits	414	Target Neighborhood Hits	334	Shared Neighborhood Hits	252
SwissProt Accessions	O14727, O43297, Q7Z438, Q9BXZ6, Q9UBZ5, Q9UGN8, Q9UGN9, Q9UGP0, Q9UJ58, Q9UJ59, Q9UJ60, Q9UJ61, Q9UJ62, Q9UJ63, Q9UJ64, Q9UJ65, Q9UJ66, Q9UJ67, Q9UNC9	Gene names	APAF1, KIAA0413
Domain Architecture
Description	Apoptotic protease-activating factor 1 (Apaf-1).

KTNB1_HUMAN
NC score	0.689205 (rank : 32)	θ value	4.0297e-08 (rank : 31)
Query Neighborhood Hits	414	Target Neighborhood Hits	349	Shared Neighborhood Hits	256
SwissProt Accessions	Q9BVA0, O60620	Gene names	KATNB1
Domain Architecture	No domain graphic available
Description	Katanin p80 WD40-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin).

KTNB1_MOUSE
NC score	0.688956 (rank : 33)	θ value	4.0297e-08 (rank : 32)
Query Neighborhood Hits	414	Target Neighborhood Hits	356	Shared Neighborhood Hits	255
SwissProt Accessions	Q8BG40, Q8CD18, Q8R1J0, Q9CWV2	Gene names	Katnb1
Domain Architecture	No domain graphic available
Description	Katanin p80 WD40-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin).

NLE1_HUMAN
NC score	0.688787 (rank : 34)	θ value	3.77169e-06 (rank : 50)
Query Neighborhood Hits	414	Target Neighborhood Hits	334	Shared Neighborhood Hits	261
SwissProt Accessions	Q9NVX2, O60868, Q9BU54	Gene names	NLE1
Domain Architecture
Description	Notchless homolog 1.

GBLP_HUMAN
NC score	0.687771 (rank : 35)	θ value	4.45536e-07 (rank : 37)
Query Neighborhood Hits	414	Target Neighborhood Hits	316	Shared Neighborhood Hits	246
SwissProt Accessions	P63244, P25388, P99049	Gene names	GNB2L1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein subunit beta 2-like 1 (Guanine nucleotide-binding protein subunit beta-like protein 12.3) (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase).

GBLP_MOUSE
NC score	0.687771 (rank : 36)	θ value	4.45536e-07 (rank : 38)
Query Neighborhood Hits	414	Target Neighborhood Hits	316	Shared Neighborhood Hits	246
SwissProt Accessions	P68040, P25388, P99049	Gene names	Gnb2l1, Gnb2-rs1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein subunit beta 2-like 1 (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) (p205) (12-3).

NLE1_MOUSE
NC score	0.686145 (rank : 37)	θ value	1.09739e-05 (rank : 59)
Query Neighborhood Hits	414	Target Neighborhood Hits	332	Shared Neighborhood Hits	260
SwissProt Accessions	Q8VEJ4	Gene names	Nle1
Domain Architecture
Description	Notchless homolog 1.

PWP2_MOUSE
NC score	0.681535 (rank : 38)	θ value	1.63604e-09 (rank : 17)
Query Neighborhood Hits	414	Target Neighborhood Hits	309	Shared Neighborhood Hits	239
SwissProt Accessions	Q8BU03, Q8BTR0	Gene names	Pwp2h
Domain Architecture
Description	Periodic tryptophan protein 2 homolog.

SMU1_HUMAN
NC score	0.681003 (rank : 39)	θ value	1.29631e-06 (rank : 45)
Query Neighborhood Hits	414	Target Neighborhood Hits	311	Shared Neighborhood Hits	243
SwissProt Accessions	Q2TAY7, Q9BU59, Q9HA96, Q9NVD1	Gene names	SMU1
Domain Architecture	No domain graphic available
Description	Smu-1 suppressor of mec-8 and unc-52 protein homolog.

SMU1_MOUSE
NC score	0.681003 (rank : 40)	θ value	1.29631e-06 (rank : 46)
Query Neighborhood Hits	414	Target Neighborhood Hits	311	Shared Neighborhood Hits	243
SwissProt Accessions	Q3UKJ7, Q6PFR6, Q8BMY4, Q9D1I8, Q9JJ70	Gene names	Smu1
Domain Architecture	No domain graphic available
Description	Smu-1 suppressor of mec-8 and unc-52 protein homolog.

PWP2_HUMAN
NC score	0.679619 (rank : 41)	θ value	1.38499e-08 (rank : 25)
Query Neighborhood Hits	414	Target Neighborhood Hits	309	Shared Neighborhood Hits	243
SwissProt Accessions	Q15269, Q96A77	Gene names	PWP2H, PWP2
Domain Architecture
Description	Periodic tryptophan protein 2 homolog.

THOC3_HUMAN
NC score	0.678825 (rank : 42)	θ value	5.81887e-07 (rank : 40)
Query Neighborhood Hits	414	Target Neighborhood Hits	294	Shared Neighborhood Hits	239
SwissProt Accessions	Q96J01	Gene names	THOC3
Domain Architecture
Description	THO complex subunit 3 (Tho3) (TEX1 homolog).

THOC3_MOUSE
NC score	0.678368 (rank : 43)	θ value	5.81887e-07 (rank : 41)
Query Neighborhood Hits	414	Target Neighborhood Hits	296	Shared Neighborhood Hits	239
SwissProt Accessions	Q8VE80, Q9CWI8	Gene names	Thoc3
Domain Architecture
Description	THO complex subunit 3 (Tho3).

STRAP_MOUSE
NC score	0.675782 (rank : 44)	θ value	1.09739e-05 (rank : 60)
Query Neighborhood Hits	414	Target Neighborhood Hits	279	Shared Neighborhood Hits	233
SwissProt Accessions	Q9Z1Z2	Gene names	Strap, Unrip
Domain Architecture
Description	Serine-threonine kinase receptor-associated protein (UNR-interacting protein).

A16L1_HUMAN
NC score	0.674763 (rank : 45)	θ value	3.52202e-12 (rank : 5)
Query Neighborhood Hits	414	Target Neighborhood Hits	664	Shared Neighborhood Hits	256
SwissProt Accessions	Q676U5, Q6IPN1, Q6UXW4, Q6ZVZ5, Q8NCY2, Q96JV5, Q9H619	Gene names	ATG16L1, APG16L
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 16-1 (APG16-like 1).

WDR71_HUMAN
NC score	0.674705 (rank : 46)	θ value	0.000158464 (rank : 87)
Query Neighborhood Hits	414	Target Neighborhood Hits	241	Shared Neighborhood Hits	206
SwissProt Accessions	Q9BRP4, Q4G165, Q53HS9, Q7Z500, Q8TBU6, Q9HAB6	Gene names	WDR71
Domain Architecture	No domain graphic available
Description	WD repeat protein 71 (Protein G-16).

STRAP_HUMAN
NC score	0.673677 (rank : 47)	θ value	1.43324e-05 (rank : 63)
Query Neighborhood Hits	414	Target Neighborhood Hits	272	Shared Neighborhood Hits	232
SwissProt Accessions	Q9Y3F4, Q9UQC8	Gene names	STRAP, MAWD, UNRIP
Domain Architecture
Description	Serine-threonine kinase receptor-associated protein (UNR-interacting protein) (WD-40 repeat protein PT-WD) (MAP activator with WD repeats).

PRP4_HUMAN
NC score	0.671029 (rank : 48)	θ value	6.43352e-06 (rank : 54)
Query Neighborhood Hits	414	Target Neighborhood Hits	309	Shared Neighborhood Hits	245
SwissProt Accessions	O43172, O43445, O43864, Q96DG2, Q96IK4	Gene names	PRPF4, PRP4
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4) (hPrp4).

TBL3_HUMAN
NC score	0.670745 (rank : 49)	θ value	0.000602161 (rank : 105)
Query Neighborhood Hits	414	Target Neighborhood Hits	286	Shared Neighborhood Hits	233
SwissProt Accessions	Q12788	Gene names	TBL3, SAZD
Domain Architecture
Description	WD repeat protein SAZD (Transducin beta-like 3 protein).

PRP4_MOUSE
NC score	0.668870 (rank : 50)	θ value	2.44474e-05 (rank : 66)
Query Neighborhood Hits	414	Target Neighborhood Hits	308	Shared Neighborhood Hits	242
SwissProt Accessions	Q9DAW6	Gene names	Prpf4
Domain Architecture	No domain graphic available
Description	U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4).

PRP17_MOUSE
NC score	0.666379 (rank : 51)	θ value	4.92598e-06 (rank : 52)
Query Neighborhood Hits	414	Target Neighborhood Hits	295	Shared Neighborhood Hits	231
SwissProt Accessions	Q9DC48	Gene names	Cdc40, Prp17
Domain Architecture
Description	Pre-mRNA-splicing factor PRP17 (Cell division cycle 40 homolog).

PRP17_HUMAN
NC score	0.663812 (rank : 52)	θ value	1.43324e-05 (rank : 62)
Query Neighborhood Hits	414	Target Neighborhood Hits	297	Shared Neighborhood Hits	232
SwissProt Accessions	O60508, O75471, Q9UPG1	Gene names	CDC40, PRP17
Domain Architecture
Description	Pre-mRNA-splicing factor PRP17 (hPRP17) (Cell division cycle 40 homolog) (EH-binding protein 3) (Ehb3).

FBXW7_MOUSE
NC score	0.657571 (rank : 53)	θ value	8.40245e-06 (rank : 57)
Query Neighborhood Hits	414	Target Neighborhood Hits	365	Shared Neighborhood Hits	248
SwissProt Accessions	Q8VBV4, Q8CCS5, Q8VHP4	Gene names	Fbxw7, Fbw7, Fbwd6, Fbxw6
Domain Architecture
Description	F-box/WD repeat protein 7 (F-box and WD-40 domain protein 7) (F-box protein FBW7) (F-box protein Fbxw6) (F-box-WD40 repeat protein 6) (SEL-10).

FBXW7_HUMAN
NC score	0.657023 (rank : 54)	θ value	8.40245e-06 (rank : 56)
Query Neighborhood Hits	414	Target Neighborhood Hits	433	Shared Neighborhood Hits	253
SwissProt Accessions	Q969H0, Q96A16, Q96LE0, Q96RI2, Q9NUX6	Gene names	FBXW7, FBW7, FBX30, SEL10
Domain Architecture
Description	F-box/WD repeat protein 7 (F-box and WD-40 domain protein 7) (F-box protein FBX30) (hCdc4) (Archipelago homolog) (hAgo) (SEL-10).

MORG1_MOUSE
NC score	0.656693 (rank : 55)	θ value	0.00298849 (rank : 129)
Query Neighborhood Hits	414	Target Neighborhood Hits	281	Shared Neighborhood Hits	227
SwissProt Accessions	Q9DAJ4, Q505C2, Q8VEB7, Q99JX9, Q9D235	Gene names	Morg1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase organizer 1 (MAPK organizer 1).

A16L1_MOUSE
NC score	0.656052 (rank : 56)	θ value	2.98157e-11 (rank : 7)
Query Neighborhood Hits	414	Target Neighborhood Hits	776	Shared Neighborhood Hits	260
SwissProt Accessions	Q8C0J2, Q6KAT7, Q80U97, Q80U98, Q80U99, Q80Y53, Q9DB63	Gene names	Atg16l1, Apg16l
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 16-1 (APG16-like 1).

WDR48_HUMAN
NC score	0.655272 (rank : 57)	θ value	0.000786445 (rank : 109)
Query Neighborhood Hits	414	Target Neighborhood Hits	291	Shared Neighborhood Hits	239
SwissProt Accessions	Q8TAF3, Q63HJ2, Q658Y1, Q8N3Z1, Q9NSK8, Q9P279	Gene names	WDR48, KIAA1449
Domain Architecture	No domain graphic available
Description	WD repeat protein 48 (WD repeat endosomal protein) (p80).

MORG1_HUMAN
NC score	0.654685 (rank : 58)	θ value	0.00228821 (rank : 125)
Query Neighborhood Hits	414	Target Neighborhood Hits	280	Shared Neighborhood Hits	229
SwissProt Accessions	Q9BRX9, Q53FT6	Gene names	MORG1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase organizer 1 (MAPK organizer 1).

COPB2_MOUSE
NC score	0.654053 (rank : 59)	θ value	9.92553e-07 (rank : 43)
Query Neighborhood Hits	414	Target Neighborhood Hits	315	Shared Neighborhood Hits	244
SwissProt Accessions	O55029, Q3U5Z9	Gene names	Copb2
Domain Architecture
Description	Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP) (p102).

COPB2_HUMAN
NC score	0.653875 (rank : 60)	θ value	9.92553e-07 (rank : 42)
Query Neighborhood Hits	414	Target Neighborhood Hits	315	Shared Neighborhood Hits	244
SwissProt Accessions	P35606	Gene names	COPB2
Domain Architecture
Description	Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP) (p102).

WDR48_MOUSE
NC score	0.652821 (rank : 61)	θ value	0.00102713 (rank : 111)
Query Neighborhood Hits	414	Target Neighborhood Hits	296	Shared Neighborhood Hits	238
SwissProt Accessions	Q8BH57, Q80TD4, Q80XI0, Q8BRM0, Q8CBK0, Q922Z9, Q9CRR1, Q9CSL0	Gene names	Wdr48, Kiaa1449
Domain Architecture	No domain graphic available
Description	WD repeat protein 48.

WDR3_HUMAN
NC score	0.651000 (rank : 62)	θ value	0.0193708 (rank : 163)
Query Neighborhood Hits	414	Target Neighborhood Hits	334	Shared Neighborhood Hits	250
SwissProt Accessions	Q9UNX4	Gene names	WDR3
Domain Architecture
Description	WD repeat protein 3.

WDR1_HUMAN
NC score	0.650895 (rank : 63)	θ value	1.87187e-05 (rank : 65)
Query Neighborhood Hits	414	Target Neighborhood Hits	292	Shared Neighborhood Hits	238
SwissProt Accessions	O75083, O75313, Q8N6E5, Q9UG05, Q9UG78, Q9UQE0	Gene names	WDR1
Domain Architecture
Description	WD repeat protein 1 (Actin-interacting protein 1) (AIP1) (NORI-1).

COPA_HUMAN
NC score	0.650685 (rank : 64)	θ value	0.0330416 (rank : 171)
Query Neighborhood Hits	414	Target Neighborhood Hits	297	Shared Neighborhood Hits	232
SwissProt Accessions	P53621	Gene names	COPA
Domain Architecture
Description	Coatomer subunit alpha (Alpha-coat protein) (Alpha-COP) (HEPCOP) (HEP- COP) [Contains: Xenin (Xenopsin-related peptide); Proxenin].

PLRG1_HUMAN
NC score	0.650043 (rank : 65)	θ value	0.00869519 (rank : 148)
Query Neighborhood Hits	414	Target Neighborhood Hits	318	Shared Neighborhood Hits	242
SwissProt Accessions	O43660, Q8WUD8	Gene names	PLRG1
Domain Architecture
Description	Pleiotropic regulator 1.

WDR17_HUMAN
NC score	0.649746 (rank : 66)	θ value	0.00020696 (rank : 91)
Query Neighborhood Hits	414	Target Neighborhood Hits	335	Shared Neighborhood Hits	254
SwissProt Accessions	Q8IZU2	Gene names	WDR17
Domain Architecture
Description	WD repeat protein 17.

WDR1_MOUSE
NC score	0.648543 (rank : 67)	θ value	0.000270298 (rank : 97)
Query Neighborhood Hits	414	Target Neighborhood Hits	296	Shared Neighborhood Hits	239
SwissProt Accessions	O88342	Gene names	Wdr1
Domain Architecture
Description	WD repeat protein 1 (Actin-interacting protein 1) (AIP1).

FBW1B_HUMAN
NC score	0.645141 (rank : 68)	θ value	0.000121331 (rank : 81)
Query Neighborhood Hits	414	Target Neighborhood Hits	327	Shared Neighborhood Hits	240
SwissProt Accessions	Q9UKB1, Q9P2S8, Q9P2S9, Q9Y4C6	Gene names	FBXW11, BTRCP2, FBW1B, FBXW1B, KIAA0696
Domain Architecture
Description	F-box/WD repeat protein 11 (F-box/WD repeat protein 1B) (F-box and WD repeats protein beta-TrCP2).

PLRG1_MOUSE
NC score	0.643406 (rank : 69)	θ value	0.0736092 (rank : 197)
Query Neighborhood Hits	414	Target Neighborhood Hits	308	Shared Neighborhood Hits	242
SwissProt Accessions	Q922V4, O55039	Gene names	Plrg1
Domain Architecture
Description	Pleiotropic regulator 1.

PK1IP_MOUSE
NC score	0.643088 (rank : 70)	θ value	6.43352e-06 (rank : 53)
Query Neighborhood Hits	414	Target Neighborhood Hits	313	Shared Neighborhood Hits	233
SwissProt Accessions	Q9DCE5, Q3UBK7, Q80UT4, Q8C5N6, Q923K2, Q9D3E9	Gene names	Pak1ip1
Domain Architecture	No domain graphic available
Description	p21-activated protein kinase-interacting protein 1 (PAK1-interacting protein 1) (Putative PAK inhibitor Skb15).

CSTF1_MOUSE
NC score	0.642609 (rank : 71)	θ value	0.00020696 (rank : 88)
Query Neighborhood Hits	414	Target Neighborhood Hits	266	Shared Neighborhood Hits	223
SwissProt Accessions	Q99LC2, Q3UMB8, Q8BJW1, Q9CSU8	Gene names	Cstf1
Domain Architecture	No domain graphic available
Description	Cleavage stimulation factor 50 kDa subunit (CSTF 50 kDa subunit) (CF-1 50 kDa subunit) (CstF-50).

FBW1A_HUMAN
NC score	0.642529 (rank : 72)	θ value	0.000121331 (rank : 80)
Query Neighborhood Hits	414	Target Neighborhood Hits	329	Shared Neighborhood Hits	240
SwissProt Accessions	Q9Y297, Q9Y213	Gene names	BTRC, BTRCP, FBW1A, FBXW1A
Domain Architecture
Description	F-box/WD repeat protein 1A (F-box and WD repeats protein beta-TrCP) (E3RSIkappaB) (pIkappaBalpha-E3 receptor subunit).

GBB2_HUMAN
NC score	0.641560 (rank : 73)	θ value	7.1131e-05 (rank : 74)
Query Neighborhood Hits	414	Target Neighborhood Hits	294	Shared Neighborhood Hits	245
SwissProt Accessions	P62879, P11016, P54312	Gene names	GNB2
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta 2 (Transducin beta chain 2) (G protein beta 2 subunit).

GBB2_MOUSE
NC score	0.641560 (rank : 74)	θ value	7.1131e-05 (rank : 75)
Query Neighborhood Hits	414	Target Neighborhood Hits	294	Shared Neighborhood Hits	245
SwissProt Accessions	P62880, P11016, P54312	Gene names	Gnb2
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta 2 (Transducin beta chain 2) (G protein beta 2 subunit).

UTP15_MOUSE
NC score	0.641045 (rank : 75)	θ value	7.1131e-05 (rank : 76)
Query Neighborhood Hits	414	Target Neighborhood Hits	309	Shared Neighborhood Hits	238
SwissProt Accessions	Q8C7V3, Q3TRG8, Q8K231	Gene names	Utp15
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 15 homolog (Src-associated protein SAW).

GBB1_HUMAN
NC score	0.637350 (rank : 76)	θ value	3.19293e-05 (rank : 68)
Query Neighborhood Hits	414	Target Neighborhood Hits	294	Shared Neighborhood Hits	239
SwissProt Accessions	P62873, P04697, P04901	Gene names	GNB1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta 1 (Transducin beta chain 1).

GBB1_MOUSE
NC score	0.637350 (rank : 77)	θ value	3.19293e-05 (rank : 69)
Query Neighborhood Hits	414	Target Neighborhood Hits	294	Shared Neighborhood Hits	239
SwissProt Accessions	P62874, P04697, P04901	Gene names	Gnb1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta 1 (Transducin beta chain 1).

WDR12_HUMAN
NC score	0.637123 (rank : 78)	θ value	0.00134147 (rank : 113)
Query Neighborhood Hits	414	Target Neighborhood Hits	300	Shared Neighborhood Hits	240
SwissProt Accessions	Q9GZL7, Q96HU0, Q9NV80, Q9NYI8	Gene names	WDR12
Domain Architecture
Description	WD repeat protein 12 (YTM1 homolog).

GBB4_HUMAN
NC score	0.633942 (rank : 79)	θ value	0.000158464 (rank : 85)
Query Neighborhood Hits	414	Target Neighborhood Hits	288	Shared Neighborhood Hits	241
SwissProt Accessions	Q9HAV0	Gene names	GNB4
Domain Architecture
Description	Guanine nucleotide-binding protein subunit beta 4 (Transducin beta chain 4).

CAF1B_HUMAN
NC score	0.633424 (rank : 80)	θ value	9.29e-05 (rank : 77)
Query Neighborhood Hits	414	Target Neighborhood Hits	345	Shared Neighborhood Hits	236
SwissProt Accessions	Q13112, Q99548	Gene names	CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7
Domain Architecture
Description	Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-Ip60) (M- phase phosphoprotein 7).

CSTF1_HUMAN
NC score	0.633421 (rank : 81)	θ value	0.00175202 (rank : 116)
Query Neighborhood Hits	414	Target Neighborhood Hits	266	Shared Neighborhood Hits	223
SwissProt Accessions	Q05048	Gene names	CSTF1
Domain Architecture
Description	Cleavage stimulation factor 50 kDa subunit (CSTF 50 kDa subunit) (CF-1 50 kDa subunit) (CstF-50).

GBB4_MOUSE
NC score	0.632898 (rank : 82)	θ value	0.00020696 (rank : 89)
Query Neighborhood Hits	414	Target Neighborhood Hits	283	Shared Neighborhood Hits	236
SwissProt Accessions	P29387, Q3TJJ1, Q8R475, Q9JHX8	Gene names	Gnb4
Domain Architecture
Description	Guanine nucleotide-binding protein subunit beta 4 (Transducin beta chain 4).

CAF1B_MOUSE
NC score	0.632843 (rank : 83)	θ value	7.1131e-05 (rank : 72)
Query Neighborhood Hits	414	Target Neighborhood Hits	385	Shared Neighborhood Hits	239
SwissProt Accessions	Q9D0N7	Gene names	Chaf1b
Domain Architecture
Description	Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-Ip60).

GBB3_MOUSE
NC score	0.631366 (rank : 84)	θ value	0.000602161 (rank : 104)
Query Neighborhood Hits	414	Target Neighborhood Hits	283	Shared Neighborhood Hits	236
SwissProt Accessions	Q61011	Gene names	Gnb3
Domain Architecture
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta 3 (Transducin beta chain 3).

WSB2_HUMAN
NC score	0.630318 (rank : 85)	θ value	0.0252991 (rank : 169)
Query Neighborhood Hits	414	Target Neighborhood Hits	308	Shared Neighborhood Hits	240
SwissProt Accessions	Q9NYS7, Q9NRX9	Gene names	WSB2
Domain Architecture
Description	WD repeat and SOCS box-containing protein 2 (WSB-2) (CS box-containing WD protein).

GBB3_HUMAN
NC score	0.629625 (rank : 86)	θ value	0.000461057 (rank : 100)
Query Neighborhood Hits	414	Target Neighborhood Hits	282	Shared Neighborhood Hits	234
SwissProt Accessions	P16520, Q9BQC0	Gene names	GNB3
Domain Architecture
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta 3 (Transducin beta chain 3).

GBB5_HUMAN
NC score	0.629403 (rank : 87)	θ value	0.00020696 (rank : 90)
Query Neighborhood Hits	414	Target Neighborhood Hits	299	Shared Neighborhood Hits	242
SwissProt Accessions	O14775, Q9HAU9	Gene names	GNB5
Domain Architecture
Description	Guanine nucleotide-binding protein subunit beta 5 (Transducin beta chain 5) (Gbeta5).

WDR12_MOUSE
NC score	0.629397 (rank : 88)	θ value	0.0431538 (rank : 184)
Query Neighborhood Hits	414	Target Neighborhood Hits	301	Shared Neighborhood Hits	244
SwissProt Accessions	Q9JJA4, Q9CST3, Q9JKF5	Gene names	Wdr12
Domain Architecture
Description	WD repeat protein 12 (YTM1 homolog).

GBB5_MOUSE
NC score	0.629260 (rank : 89)	θ value	0.000270298 (rank : 92)
Query Neighborhood Hits	414	Target Neighborhood Hits	298	Shared Neighborhood Hits	242
SwissProt Accessions	P62881, O35354, P54314, Q91WB3	Gene names	Gnb5
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein subunit beta 5 (Transducin beta chain 5) (Gbeta5).

WSB2_MOUSE
NC score	0.628545 (rank : 90)	θ value	0.0113563 (rank : 157)
Query Neighborhood Hits	414	Target Neighborhood Hits	306	Shared Neighborhood Hits	238
SwissProt Accessions	O54929, Q9R1M8	Gene names	Wsb2, Swip2
Domain Architecture
Description	WD repeat and SOCS box-containing protein 2 (WSB-2) (SOCS box- containing WD protein SWiP-2).

WDR26_HUMAN
NC score	0.627374 (rank : 91)	θ value	0.0431538 (rank : 185)
Query Neighborhood Hits	414	Target Neighborhood Hits	294	Shared Neighborhood Hits	245
SwissProt Accessions	Q9H7D7, Q86UY4	Gene names	WDR26
Domain Architecture
Description	WD repeat protein 26.

WSB1_HUMAN
NC score	0.627272 (rank : 92)	θ value	0.00298849 (rank : 134)
Query Neighborhood Hits	414	Target Neighborhood Hits	337	Shared Neighborhood Hits	242
SwissProt Accessions	Q9Y6I7, Q9NRB1, Q9UBH9, Q9UNN6	Gene names	WSB1, SWIP1
Domain Architecture
Description	WD repeat and SOCS box-containing protein 1 (WSB-1) (SOCS box- containing WD protein SWiP-1).

WDR26_MOUSE
NC score	0.627227 (rank : 93)	θ value	0.0330416 (rank : 178)
Query Neighborhood Hits	414	Target Neighborhood Hits	295	Shared Neighborhood Hits	245
SwissProt Accessions	Q8C6G8, Q8C4F3, Q8VDZ6	Gene names	Wdr26
Domain Architecture
Description	WD repeat protein 26.

AAMP_HUMAN
NC score	0.626409 (rank : 94)	θ value	0.125558 (rank : 204)
Query Neighborhood Hits	414	Target Neighborhood Hits	294	Shared Neighborhood Hits	231
SwissProt Accessions	Q13685, Q8WUJ9, Q96H92	Gene names	AAMP
Domain Architecture
Description	Angio-associated migratory cell protein.

U3IP2_HUMAN
NC score	0.624168 (rank : 95)	θ value	0.00228821 (rank : 126)
Query Neighborhood Hits	414	Target Neighborhood Hits	307	Shared Neighborhood Hits	227
SwissProt Accessions	O43818, Q8IZ30	Gene names	RNU3IP2, U355K
Domain Architecture
Description	U3 small nucleolar RNA-interacting protein 2 (U3 small nucleolar ribonucleoprotein-associated 55 kDa protein) (U3 snoRNP-associated 55 kDa protein) (U3-55K).

WSB1_MOUSE
NC score	0.623512 (rank : 96)	θ value	0.00175202 (rank : 120)
Query Neighborhood Hits	414	Target Neighborhood Hits	313	Shared Neighborhood Hits	235
SwissProt Accessions	O54927	Gene names	Wsb1
Domain Architecture
Description	WD repeat and SOCS box-containing protein 1 (WSB-1).

WDR31_HUMAN
NC score	0.620625 (rank : 97)	θ value	0.0193708 (rank : 162)
Query Neighborhood Hits	414	Target Neighborhood Hits	282	Shared Neighborhood Hits	232
SwissProt Accessions	Q8NA23, Q96EG8	Gene names	WDR31
Domain Architecture
Description	WD repeat protein 31.

PK1IP_HUMAN
NC score	0.620215 (rank : 98)	θ value	9.29e-05 (rank : 78)
Query Neighborhood Hits	414	Target Neighborhood Hits	277	Shared Neighborhood Hits	222
SwissProt Accessions	Q9NWT1, Q5T4J2, Q96QJ8, Q96T87	Gene names	PAK1IP1, PIP1, WDR84
Domain Architecture	No domain graphic available
Description	p21-activated protein kinase-interacting protein 1 (PAK1-interacting protein 1) (PAK/PLC-interacting protein 1) (hPIP1) (WD repeat protein 84).

WDR31_MOUSE
NC score	0.620096 (rank : 99)	θ value	0.125558 (rank : 214)
Query Neighborhood Hits	414	Target Neighborhood Hits	287	Shared Neighborhood Hits	229
SwissProt Accessions	Q9JHB4, Q3URZ0, Q9D3N4	Gene names	Wdr31
Domain Architecture
Description	WD repeat protein 31 (Spermatid WD repeat protein) (spWD).

U3IP2_MOUSE
NC score	0.618762 (rank : 100)	θ value	0.00665767 (rank : 144)
Query Neighborhood Hits	414	Target Neighborhood Hits	312	Shared Neighborhood Hits	224
SwissProt Accessions	Q91WM3, Q8CFB7	Gene names	Rnu3ip2, U3-55k
Domain Architecture
Description	U3 small nucleolar RNA-interacting protein 2 (U3 small nucleolar ribonucleoprotein-associated 55 kDa protein) (U3 snoRNP-associated 55 kDa protein) (U3-55K).

PEX7_MOUSE
NC score	0.616434 (rank : 101)	θ value	0.00298849 (rank : 130)
Query Neighborhood Hits	414	Target Neighborhood Hits	279	Shared Neighborhood Hits	226
SwissProt Accessions	P97865	Gene names	Pex7
Domain Architecture
Description	Peroxisomal targeting signal 2 receptor (PTS2 receptor) (Peroxin-7).

UTP15_HUMAN
NC score	0.614849 (rank : 102)	θ value	0.0113563 (rank : 155)
Query Neighborhood Hits	414	Target Neighborhood Hits	296	Shared Neighborhood Hits	233
SwissProt Accessions	Q8TED0, Q6IA60, Q96E08, Q9H9F8	Gene names	UTP15
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 15 homolog.

PEX7_HUMAN
NC score	0.613097 (rank : 103)	θ value	0.0961366 (rank : 202)
Query Neighborhood Hits	414	Target Neighborhood Hits	275	Shared Neighborhood Hits	226
SwissProt Accessions	O00628	Gene names	PEX7, PTS2R
Domain Architecture
Description	Peroxisomal targeting signal 2 receptor (PTS2 receptor) (Peroxin-7).

FBXW2_HUMAN
NC score	0.611497 (rank : 104)	θ value	0.000461057 (rank : 99)
Query Neighborhood Hits	414	Target Neighborhood Hits	260	Shared Neighborhood Hits	206
SwissProt Accessions	Q9UKT8, Q7Z4V6, Q8WV51, Q9HA09, Q9UKA3	Gene names	FBXW2, FBW2, FWD2
Domain Architecture
Description	F-box/WD repeat protein 2 (F-box and WD-40 domain protein 2) (MD6 protein).

BRWD1_MOUSE
NC score	0.610464 (rank : 105)	θ value	2.21117e-06 (rank : 47)
Query Neighborhood Hits	414	Target Neighborhood Hits	478	Shared Neighborhood Hits	255
SwissProt Accessions	Q921C3, Q921C2	Gene names	Brwd1, Wdr9
Domain Architecture	No domain graphic available
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

CDC20_MOUSE
NC score	0.609744 (rank : 106)	θ value	0.0330416 (rank : 170)
Query Neighborhood Hits	414	Target Neighborhood Hits	325	Shared Neighborhood Hits	237
SwissProt Accessions	Q9JJ66, Q3TGP1, Q8BPG4, Q99LK3	Gene names	Cdc20
Domain Architecture
Description	Cell division cycle protein 20 homolog (p55CDC) (mmCdc20).

STRN4_MOUSE
NC score	0.609672 (rank : 107)	θ value	0.000158464 (rank : 86)
Query Neighborhood Hits	414	Target Neighborhood Hits	324	Shared Neighborhood Hits	245
SwissProt Accessions	P58404, Q68EF5	Gene names	Strn4, Zin
Domain Architecture
Description	Striatin-4 (Zinedin).

HIRA_MOUSE
NC score	0.609443 (rank : 108)	θ value	5.44631e-05 (rank : 70)
Query Neighborhood Hits	414	Target Neighborhood Hits	274	Shared Neighborhood Hits	228
SwissProt Accessions	Q61666, O08845, Q62365	Gene names	Hira, Tuple1
Domain Architecture
Description	HIRA protein (TUP1-like enhancer of split protein 1).

STRN4_HUMAN
NC score	0.609429 (rank : 109)	θ value	0.000786445 (rank : 108)
Query Neighborhood Hits	414	Target Neighborhood Hits	325	Shared Neighborhood Hits	244
SwissProt Accessions	Q9NRL3	Gene names	STRN4, ZIN
Domain Architecture
Description	Striatin-4 (Zinedin).

HIRA_HUMAN
NC score	0.609428 (rank : 110)	θ value	1.09739e-05 (rank : 58)
Query Neighborhood Hits	414	Target Neighborhood Hits	279	Shared Neighborhood Hits	230
SwissProt Accessions	P54198, Q8IXN2	Gene names	HIRA, DGCR1, HIR, TUPLE1
Domain Architecture
Description	HIRA protein (TUP1-like enhancer of split protein 1).

CDC20_HUMAN
NC score	0.607596 (rank : 111)	θ value	0.0961366 (rank : 199)
Query Neighborhood Hits	414	Target Neighborhood Hits	329	Shared Neighborhood Hits	233
SwissProt Accessions	Q12834, Q9BW56, Q9UQI9	Gene names	CDC20
Domain Architecture
Description	Cell division cycle protein 20 homolog (p55CDC).

FBXW2_MOUSE
NC score	0.605689 (rank : 112)	θ value	0.00228821 (rank : 123)
Query Neighborhood Hits	414	Target Neighborhood Hits	249	Shared Neighborhood Hits	204
SwissProt Accessions	Q60584	Gene names	Fbxw2
Domain Architecture
Description	F-box/WD repeat protein 2 (F-box and WD-40 domain protein 2) (MD6 protein).

BRWD1_HUMAN
NC score	0.605034 (rank : 113)	θ value	2.88788e-06 (rank : 48)
Query Neighborhood Hits	414	Target Neighborhood Hits	448	Shared Neighborhood Hits	250
SwissProt Accessions	Q9NSI6, O43721, Q5R2V0, Q5R2V1, Q8TCV3, Q96QG9, Q96QH0, Q9NUK1	Gene names	BRWD1, C21orf107, WDR9
Domain Architecture
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

TEP1_HUMAN
NC score	0.603823 (rank : 114)	θ value	0.00665767 (rank : 143)
Query Neighborhood Hits	414	Target Neighborhood Hits	371	Shared Neighborhood Hits	245
SwissProt Accessions	Q99973	Gene names	TEP1, TLP1, TP1
Domain Architecture
Description	Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 telomerase homolog).

WDR16_MOUSE
NC score	0.603092 (rank : 115)	θ value	0.00665767 (rank : 145)
Query Neighborhood Hits	414	Target Neighborhood Hits	269	Shared Neighborhood Hits	218
SwissProt Accessions	Q5F201, Q5F200, Q9D432, Q9DA68	Gene names	WDR16
Domain Architecture	No domain graphic available
Description	WD repeat protein 16.

FZR_MOUSE
NC score	0.599989 (rank : 116)	θ value	0.0148317 (rank : 159)
Query Neighborhood Hits	414	Target Neighborhood Hits	283	Shared Neighborhood Hits	235
SwissProt Accessions	Q9R1K5	Gene names	Fzr1, Fyr, Fzr
Domain Architecture
Description	Fizzy-related protein homolog (Fzr) (Cdh1/Hct1 homolog).

WDR16_HUMAN
NC score	0.597861 (rank : 117)	θ value	0.0252991 (rank : 167)
Query Neighborhood Hits	414	Target Neighborhood Hits	275	Shared Neighborhood Hits	220
SwissProt Accessions	Q8N1V2, Q5DX23, Q8TC73, Q8TCI3	Gene names	WDR16, WDRPUH
Domain Architecture	No domain graphic available
Description	WD repeat protein 16 (WD40-repeat protein up-regulated in HCC).

WDR37_MOUSE
NC score	0.597677 (rank : 118)	θ value	0.62314 (rank : 266)
Query Neighborhood Hits	414	Target Neighborhood Hits	298	Shared Neighborhood Hits	223
SwissProt Accessions	Q8CBE3, Q80Y96, Q8CCL2	Gene names	Wdr37, Kiaa0982
Domain Architecture
Description	WD repeat protein 37.

WDR36_HUMAN
NC score	0.597134 (rank : 119)	θ value	0.0330416 (rank : 179)
Query Neighborhood Hits	414	Target Neighborhood Hits	274	Shared Neighborhood Hits	226
SwissProt Accessions	Q8NI36, Q8N1Q2	Gene names	WDR36
Domain Architecture
Description	WD repeat protein 36 (T-cell activation WD repeat-containing protein) (TA-WDRP).

FZR_HUMAN
NC score	0.596806 (rank : 120)	θ value	0.0961366 (rank : 200)
Query Neighborhood Hits	414	Target Neighborhood Hits	279	Shared Neighborhood Hits	232
SwissProt Accessions	Q9UM11, O75869, Q86U66, Q96NW8, Q9UI96, Q9ULH8, Q9UM10, Q9UNQ1, Q9Y2T8	Gene names	FZR1, CDH1, FYR, FZR, KIAA1242
Domain Architecture
Description	Fizzy-related protein homolog (Fzr) (Cdh1/Hct1 homolog) (hCDH1) (CDC20-like protein 1).

WDR33_HUMAN
NC score	0.596080 (rank : 121)	θ value	6.43352e-06 (rank : 55)
Query Neighborhood Hits	414	Target Neighborhood Hits	638	Shared Neighborhood Hits	258
SwissProt Accessions	Q9C0J8	Gene names	WDR33, WDC146
Domain Architecture
Description	WD repeat protein 33 (WD repeat protein WDC146).

WDR37_HUMAN
NC score	0.595939 (rank : 122)	θ value	1.06291 (rank : 291)
Query Neighborhood Hits	414	Target Neighborhood Hits	303	Shared Neighborhood Hits	222
SwissProt Accessions	Q9Y2I8, Q5SW03, Q9NTJ6	Gene names	WDR37, KIAA0982
Domain Architecture
Description	WD repeat protein 37.

STRN3_HUMAN
NC score	0.590229 (rank : 123)	θ value	1.09739e-05 (rank : 61)
Query Neighborhood Hits	414	Target Neighborhood Hits	316	Shared Neighborhood Hits	228
SwissProt Accessions	Q13033, Q9NRA5	Gene names	STRN3, GS2NA, SG2NA
Domain Architecture
Description	Striatin-3 (Cell-cycle autoantigen SG2NA) (S/G2 antigen).

TEP1_MOUSE
NC score	0.589238 (rank : 124)	θ value	0.0330416 (rank : 175)
Query Neighborhood Hits	414	Target Neighborhood Hits	344	Shared Neighborhood Hits	246
SwissProt Accessions	P97499	Gene names	Tep1, Tp1
Domain Architecture
Description	Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 homolog).

STRN3_MOUSE
NC score	0.589131 (rank : 125)	θ value	1.43324e-05 (rank : 64)
Query Neighborhood Hits	414	Target Neighborhood Hits	309	Shared Neighborhood Hits	224
SwissProt Accessions	Q9ERG2	Gene names	Strn3, Gs2na, Sg2na
Domain Architecture
Description	Striatin-3 (Cell-cycle autoantigen SG2NA) (S/G2 antigen).

STRN_MOUSE
NC score	0.588978 (rank : 126)	θ value	0.000121331 (rank : 82)
Query Neighborhood Hits	414	Target Neighborhood Hits	326	Shared Neighborhood Hits	240
SwissProt Accessions	O55106	Gene names	Strn
Domain Architecture
Description	Striatin.

WDR47_MOUSE
NC score	0.586536 (rank : 127)	θ value	0.365318 (rank : 248)
Query Neighborhood Hits	414	Target Neighborhood Hits	295	Shared Neighborhood Hits	222
SwissProt Accessions	Q8CGF6, Q80TP4	Gene names	Wdr47, Kiaa0893
Domain Architecture	No domain graphic available
Description	WD repeat protein 47.

TBL2_HUMAN
NC score	0.586137 (rank : 128)	θ value	0.000461057 (rank : 101)
Query Neighborhood Hits	414	Target Neighborhood Hits	225	Shared Neighborhood Hits	197
SwissProt Accessions	Q9Y4P3, Q9UQE2	Gene names	TBL2, WBSCR13
Domain Architecture
Description	Transducin beta-like 2 protein (WS beta-transducin repeats protein) (WS-betaTRP) (Williams-Beuren syndrome chromosome region 13 protein).

STRN_HUMAN
NC score	0.585789 (rank : 129)	θ value	5.44631e-05 (rank : 71)
Query Neighborhood Hits	414	Target Neighborhood Hits	308	Shared Neighborhood Hits	233
SwissProt Accessions	O43815, Q9NP38	Gene names	STRN
Domain Architecture
Description	Striatin.

WDR47_HUMAN
NC score	0.585278 (rank : 130)	θ value	0.365318 (rank : 247)
Query Neighborhood Hits	414	Target Neighborhood Hits	295	Shared Neighborhood Hits	221
SwissProt Accessions	O94967, Q8IXT7, Q8IYU9	Gene names	WDR47, KIAA0893
Domain Architecture	No domain graphic available
Description	WD repeat protein 47.

PLAP_HUMAN
NC score	0.585014 (rank : 131)	θ value	0.125558 (rank : 211)
Query Neighborhood Hits	414	Target Neighborhood Hits	266	Shared Neighborhood Hits	209
SwissProt Accessions	Q9Y263, Q53EU5, Q5VY33, Q9NUL8, Q9NVE9, Q9UF53, Q9Y5L1	Gene names	PLAA, PLAP
Domain Architecture
Description	Phospholipase A-2-activating protein (PLAP) (PLA2P).

PLAP_MOUSE
NC score	0.582325 (rank : 132)	θ value	0.125558 (rank : 212)
Query Neighborhood Hits	414	Target Neighborhood Hits	261	Shared Neighborhood Hits	209
SwissProt Accessions	P27612, Q8C6C4	Gene names	Plaa, Plap
Domain Architecture
Description	Phospholipase A-2-activating protein (PLAP).

IF122_HUMAN
NC score	0.579813 (rank : 133)	θ value	0.000270298 (rank : 93)
Query Neighborhood Hits	414	Target Neighborhood Hits	244	Shared Neighborhood Hits	206
SwissProt Accessions	Q9HBG6	Gene names	IFT122, WDR10, WDR140
Domain Architecture
Description	Intraflagellar transport 122 homolog (WD repeat protein 10).

ERCC8_HUMAN
NC score	0.578941 (rank : 134)	θ value	0.62314 (rank : 259)
Query Neighborhood Hits	414	Target Neighborhood Hits	267	Shared Neighborhood Hits	226
SwissProt Accessions	Q13216, Q6FHX5, Q96GB9	Gene names	ERCC8, CKN1, CSA
Domain Architecture
Description	DNA excision repair protein ERCC-8 (Cockayne syndrome WD repeat protein CSA).

ERCC8_MOUSE
NC score	0.577874 (rank : 135)	θ value	0.365318 (rank : 239)
Query Neighborhood Hits	414	Target Neighborhood Hits	269	Shared Neighborhood Hits	226
SwissProt Accessions	Q8CFD5, Q3U066, Q8VDC4, Q9CWK7	Gene names	Ercc8, Ckn1, Csa
Domain Architecture	No domain graphic available
Description	DNA excision repair protein ERCC-8 (Cockayne syndrome WD repeat protein CSA homolog).

WDR23_MOUSE
NC score	0.575397 (rank : 136)	θ value	0.00509761 (rank : 142)
Query Neighborhood Hits	414	Target Neighborhood Hits	271	Shared Neighborhood Hits	218
SwissProt Accessions	Q91VU6, Q3U836, Q8JZV8	Gene names	Wdr23, D14Ucla1
Domain Architecture
Description	WD repeat protein 23.

GRWD1_HUMAN
NC score	0.572774 (rank : 137)	θ value	0.0113563 (rank : 151)
Query Neighborhood Hits	414	Target Neighborhood Hits	297	Shared Neighborhood Hits	243
SwissProt Accessions	Q9BQ67	Gene names	GRWD1, GRWD, WDR28
Domain Architecture
Description	Glutamate-rich WD repeat-containing protein 1.

WDR23_HUMAN
NC score	0.569395 (rank : 138)	θ value	0.0252991 (rank : 168)
Query Neighborhood Hits	414	Target Neighborhood Hits	267	Shared Neighborhood Hits	219
SwissProt Accessions	Q8TEB1, Q86U00, Q86U39, Q8NDN2, Q9H2J0, Q9H3A3, Q9H5C9	Gene names	WDR23
Domain Architecture
Description	WD repeat protein 23.

TRAF7_MOUSE
NC score	0.568541 (rank : 139)	θ value	0.000270298 (rank : 95)
Query Neighborhood Hits	414	Target Neighborhood Hits	470	Shared Neighborhood Hits	215
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

TRAF7_HUMAN
NC score	0.566108 (rank : 140)	θ value	0.000270298 (rank : 94)
Query Neighborhood Hits	414	Target Neighborhood Hits	482	Shared Neighborhood Hits	215
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

WDR55_HUMAN
NC score	0.564133 (rank : 141)	θ value	1.81305 (rank : 311)
Query Neighborhood Hits	414	Target Neighborhood Hits	231	Shared Neighborhood Hits	197
SwissProt Accessions	Q9H6Y2	Gene names	WDR55
Domain Architecture	No domain graphic available
Description	WD repeat protein 55.

GRWD1_MOUSE
NC score	0.563232 (rank : 142)	θ value	0.0961366 (rank : 201)
Query Neighborhood Hits	414	Target Neighborhood Hits	296	Shared Neighborhood Hits	240
SwissProt Accessions	Q810D6, Q922H3	Gene names	Grwd1, A301
Domain Architecture	No domain graphic available
Description	Glutamate-rich WD repeat-containing protein 1 (Protein A301).

WDR55_MOUSE
NC score	0.558526 (rank : 143)	θ value	0.125558 (rank : 217)
Query Neighborhood Hits	414	Target Neighborhood Hits	236	Shared Neighborhood Hits	197
SwissProt Accessions	Q9CX97	Gene names	Wdr55
Domain Architecture	No domain graphic available
Description	WD repeat protein 55.

NEDD1_MOUSE
NC score	0.556960 (rank : 144)	θ value	0.00869519 (rank : 147)
Query Neighborhood Hits	414	Target Neighborhood Hits	281	Shared Neighborhood Hits	206
SwissProt Accessions	P33215, Q6NXV3, Q8BN12, Q8BN86, Q8BQL9, Q9CWK2	Gene names	Nedd1, Nedd-1
Domain Architecture	No domain graphic available
Description	Protein NEDD1 (Neural precursor cell expressed developmentally down- regulated protein 1).

WDR53_MOUSE
NC score	0.554291 (rank : 145)	θ value	0.0330416 (rank : 180)
Query Neighborhood Hits	414	Target Neighborhood Hits	254	Shared Neighborhood Hits	213
SwissProt Accessions	Q9DB94	Gene names	Wdr53
Domain Architecture	No domain graphic available
Description	WD repeat protein 53.

MEP50_MOUSE
NC score	0.552933 (rank : 146)	θ value	0.0563607 (rank : 188)
Query Neighborhood Hits	414	Target Neighborhood Hits	271	Shared Neighborhood Hits	215
SwissProt Accessions	Q99J09, Q3TFJ1, Q8BSH8, Q9CZY5	Gene names	Wdr77, Mep50
Domain Architecture
Description	Methylosome protein 50 (MEP50 protein) (WD repeat protein 77).

WDR53_HUMAN
NC score	0.551316 (rank : 147)	θ value	0.125558 (rank : 216)
Query Neighborhood Hits	414	Target Neighborhood Hits	251	Shared Neighborhood Hits	217
SwissProt Accessions	Q7Z5U6	Gene names	WDR53
Domain Architecture	No domain graphic available
Description	WD repeat protein 53.

NEDD1_HUMAN
NC score	0.550049 (rank : 148)	θ value	0.00509761 (rank : 140)
Query Neighborhood Hits	414	Target Neighborhood Hits	294	Shared Neighborhood Hits	206
SwissProt Accessions	Q8NHV4, Q8NA30	Gene names	NEDD1
Domain Architecture	No domain graphic available
Description	Protein NEDD1.

WDR18_MOUSE
NC score	0.549467 (rank : 149)	θ value	0.0736092 (rank : 198)
Query Neighborhood Hits	414	Target Neighborhood Hits	239	Shared Neighborhood Hits	198
SwissProt Accessions	Q4VBE8	Gene names	Wdr18
Domain Architecture	No domain graphic available
Description	WD repeat protein 18.

TBL2_MOUSE
NC score	0.548249 (rank : 150)	θ value	0.0330416 (rank : 174)
Query Neighborhood Hits	414	Target Neighborhood Hits	221	Shared Neighborhood Hits	194
SwissProt Accessions	Q9R099	Gene names	Tbl2
Domain Architecture
Description	Transducin beta-like 2 protein.

MEP50_HUMAN
NC score	0.548099 (rank : 151)	θ value	0.125558 (rank : 210)
Query Neighborhood Hits	414	Target Neighborhood Hits	268	Shared Neighborhood Hits	212
SwissProt Accessions	Q9BQA1, Q96GK4, Q9BWY3	Gene names	WDR77, MEP50
Domain Architecture
Description	Methylosome protein 50 (MEP50 protein) (WD repeat protein 77).

WDR18_HUMAN
NC score	0.547212 (rank : 152)	θ value	1.38821 (rank : 298)
Query Neighborhood Hits	414	Target Neighborhood Hits	246	Shared Neighborhood Hits	207
SwissProt Accessions	Q9BV38, O60390, Q9BWR2	Gene names	WDR18
Domain Architecture
Description	WD repeat protein 18.

FAN_HUMAN
NC score	0.547084 (rank : 153)	θ value	1.29631e-06 (rank : 44)
Query Neighborhood Hits	414	Target Neighborhood Hits	295	Shared Neighborhood Hits	230
SwissProt Accessions	Q92636	Gene names	NSMAF, FAN
Domain Architecture
Description	Protein FAN (Factor associated with N-SMase activation) (Factor associated with neutral sphingomyelinase activation).

WDR65_HUMAN
NC score	0.546600 (rank : 154)	θ value	1.06291 (rank : 292)
Query Neighborhood Hits	414	Target Neighborhood Hits	238	Shared Neighborhood Hits	203
SwissProt Accessions	Q96MR6, Q5TAI0	Gene names	WDR65
Domain Architecture	No domain graphic available
Description	WD repeat protein 65.

RBBP5_HUMAN
NC score	0.546585 (rank : 155)	θ value	0.0113563 (rank : 152)
Query Neighborhood Hits	414	Target Neighborhood Hits	372	Shared Neighborhood Hits	191
SwissProt Accessions	Q15291	Gene names	RBBP5, RBQ3
Domain Architecture
Description	Retinoblastoma-binding protein 5 (RBBP-5) (Retinoblastoma-binding protein RBQ-3).

FAN_MOUSE
NC score	0.536223 (rank : 156)	θ value	4.92598e-06 (rank : 51)
Query Neighborhood Hits	414	Target Neighborhood Hits	292	Shared Neighborhood Hits	222
SwissProt Accessions	O35242	Gene names	Nsmaf, Fan
Domain Architecture
Description	Protein FAN (Factor associated with N-SMase activation) (Factor associated with neutral sphingomyelinase activation).

IF32_MOUSE
NC score	0.533114 (rank : 157)	θ value	8.99809 (rank : 399)
Query Neighborhood Hits	414	Target Neighborhood Hits	239	Shared Neighborhood Hits	197
SwissProt Accessions	Q9QZD9	Gene names	Eif3s2, Trip1
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 2 (eIF-3 beta) (eIF3 p36) (eIF3i) (TGF-beta receptor-interacting protein 1) (TRIP-1).

IF32_HUMAN
NC score	0.533035 (rank : 158)	θ value	6.88961 (rank : 371)
Query Neighborhood Hits	414	Target Neighborhood Hits	239	Shared Neighborhood Hits	197
SwissProt Accessions	Q13347	Gene names	EIF3S2, TRIP1
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 2 (eIF-3 beta) (eIF3 p36) (eIF3i) (TGF-beta receptor-interacting protein 1) (TRIP-1).

GNB1L_MOUSE
NC score	0.525533 (rank : 159)	θ value	1.06291 (rank : 285)
Query Neighborhood Hits	414	Target Neighborhood Hits	231	Shared Neighborhood Hits	188
SwissProt Accessions	Q9EQ15, Q8R1F3, Q9CWP2, Q9D3Y1	Gene names	Gnb1l, Estm55, Wdr14
Domain Architecture
Description	Guanine nucleotide-binding protein subunit beta-like protein 1 (G protein subunit beta-like protein 1) (WD40 repeat-containing protein deleted in VCFS) (Protein WDVCF).

PWP1_MOUSE
NC score	0.525442 (rank : 160)	θ value	8.99809 (rank : 404)
Query Neighborhood Hits	414	Target Neighborhood Hits	278	Shared Neighborhood Hits	212
SwissProt Accessions	Q99LL5, Q9D6T6	Gene names	Pwp1
Domain Architecture	No domain graphic available
Description	Periodic tryptophan protein 1 homolog.

WDR24_MOUSE
NC score	0.524103 (rank : 161)	θ value	0.00175202 (rank : 119)
Query Neighborhood Hits	414	Target Neighborhood Hits	286	Shared Neighborhood Hits	209
SwissProt Accessions	Q8CFJ9	Gene names	Wdr24
Domain Architecture	No domain graphic available
Description	WD repeat protein 24.

BOP1_MOUSE
NC score	0.524002 (rank : 162)	θ value	0.0113563 (rank : 149)
Query Neighborhood Hits	414	Target Neighborhood Hits	267	Shared Neighborhood Hits	211
SwissProt Accessions	P97452, Q3TK87, Q91X31	Gene names	Bop1
Domain Architecture
Description	Ribosome biogenesis protein BOP1 (Block of proliferation 1 protein).

RAE1L_HUMAN
NC score	0.521638 (rank : 163)	θ value	0.47712 (rank : 252)
Query Neighborhood Hits	414	Target Neighborhood Hits	222	Shared Neighborhood Hits	194
SwissProt Accessions	P78406, O15306, Q3SYL7, Q5TCH8, Q6V708, Q9H100, Q9NQM6	Gene names	RAE1, MRNP41
Domain Architecture
Description	mRNA-associated protein mrnp 41 (Rae1 protein homolog).

WDR22_MOUSE
NC score	0.520555 (rank : 164)	θ value	0.0330416 (rank : 177)
Query Neighborhood Hits	414	Target Neighborhood Hits	302	Shared Neighborhood Hits	206
SwissProt Accessions	Q80T85, Q80VT3, Q80ZW6, Q8BIP8, Q8BVK5, Q8K0Q6	Gene names	Wdr22, Kiaa1824
Domain Architecture
Description	WD repeat protein 22.

RAE1L_MOUSE
NC score	0.519630 (rank : 165)	θ value	1.06291 (rank : 289)
Query Neighborhood Hits	414	Target Neighborhood Hits	225	Shared Neighborhood Hits	194
SwissProt Accessions	Q8C570, Q3UKD4	Gene names	Rae1, Mrnp41
Domain Architecture	No domain graphic available
Description	mRNA-associated protein mrnp 41 (Rae1 protein homolog).

WDR22_HUMAN
NC score	0.518940 (rank : 166)	θ value	0.0330416 (rank : 176)
Query Neighborhood Hits	414	Target Neighborhood Hits	328	Shared Neighborhood Hits	212
SwissProt Accessions	Q96JK2, O60559, Q8N3V3, Q8N3V5	Gene names	WDR22, BCRG2, KIAA1824
Domain Architecture
Description	WD repeat protein 22 (Breakpoint cluster region protein 2) (BCRP2).

PWP1_HUMAN
NC score	0.517707 (rank : 167)	θ value	2.36792 (rank : 319)
Query Neighborhood Hits	414	Target Neighborhood Hits	261	Shared Neighborhood Hits	210
SwissProt Accessions	Q13610	Gene names	PWP1
Domain Architecture
Description	Periodic tryptophan protein 1 homolog (Keratinocyte protein IEF SSP 9502).

GEMI5_MOUSE
NC score	0.517150 (rank : 168)	θ value	0.0330416 (rank : 172)
Query Neighborhood Hits	414	Target Neighborhood Hits	424	Shared Neighborhood Hits	245
SwissProt Accessions	Q8BX17	Gene names	Gemin5
Domain Architecture
Description	Gem-associated protein 5 (Gemin5).

GEMI5_HUMAN
NC score	0.516208 (rank : 169)	θ value	0.0113563 (rank : 150)
Query Neighborhood Hits	414	Target Neighborhood Hits	362	Shared Neighborhood Hits	239
SwissProt Accessions	Q8TEQ6, Q8WWV4, Q969W4, Q9H9K3, Q9UFI5	Gene names	GEMIN5
Domain Architecture
Description	Gem-associated protein 5 (Gemin5).

SEC13_MOUSE
NC score	0.516039 (rank : 170)	θ value	0.0563607 (rank : 190)
Query Neighborhood Hits	414	Target Neighborhood Hits	195	Shared Neighborhood Hits	179
SwissProt Accessions	Q9D1M0, Q99M12, Q9D712	Gene names	Sec13l1
Domain Architecture	No domain graphic available
Description	SEC13-related protein (SEC13-like protein 1).

SEC13_HUMAN
NC score	0.512631 (rank : 171)	θ value	0.0113563 (rank : 154)
Query Neighborhood Hits	414	Target Neighborhood Hits	199	Shared Neighborhood Hits	177
SwissProt Accessions	P55735, Q9BRM6, Q9BUG7	Gene names	SEC13L1, SEC13R
Domain Architecture	No domain graphic available
Description	SEC13-related protein (SEC13-like protein 1).

RBBP4_MOUSE
NC score	0.511890 (rank : 172)	θ value	0.47712 (rank : 254)
Query Neighborhood Hits	414	Target Neighborhood Hits	289	Shared Neighborhood Hits	231
SwissProt Accessions	Q60972	Gene names	Rbbp4, Rbap48
Domain Architecture
Description	Histone-binding protein RBBP4 (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48) (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome remodeling factor subunit RBAP48).

AHI1_MOUSE
NC score	0.511312 (rank : 173)	θ value	0.000158464 (rank : 83)
Query Neighborhood Hits	414	Target Neighborhood Hits	496	Shared Neighborhood Hits	224
SwissProt Accessions	Q8K3E5, Q7TNV2, Q9CVY1	Gene names	Ahi1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein) (AHI-1).

WDR49_HUMAN
NC score	0.511045 (rank : 174)	θ value	1.38821 (rank : 300)
Query Neighborhood Hits	414	Target Neighborhood Hits	214	Shared Neighborhood Hits	174
SwissProt Accessions	Q8IV35, Q8N297	Gene names	WDR49
Domain Architecture	No domain graphic available
Description	WD repeat protein 49.

RBBP4_HUMAN
NC score	0.510816 (rank : 175)	θ value	0.47712 (rank : 253)
Query Neighborhood Hits	414	Target Neighborhood Hits	291	Shared Neighborhood Hits	233
SwissProt Accessions	Q09028, P31149, Q53H02, Q96BV9	Gene names	RBBP4, RBAP48
Domain Architecture
Description	Histone-binding protein RBBP4 (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48) (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome remodeling factor subunit RBAP48).

AHI1_HUMAN
NC score	0.505176 (rank : 176)	θ value	3.77169e-06 (rank : 49)
Query Neighborhood Hits	414	Target Neighborhood Hits	537	Shared Neighborhood Hits	217
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

CORO7_MOUSE
NC score	0.504788 (rank : 177)	θ value	0.00298849 (rank : 127)
Query Neighborhood Hits	414	Target Neighborhood Hits	312	Shared Neighborhood Hits	239
SwissProt Accessions	Q9D2V7, Q3UDJ4, Q6P8Y8, Q8C9V7	Gene names	Coro7
Domain Architecture
Description	Coronin-7 (70 kDa WD repeat tumor rejection antigen homolog).

RBBP7_HUMAN
NC score	0.501581 (rank : 178)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	414	Target Neighborhood Hits	285	Shared Neighborhood Hits	230
SwissProt Accessions	Q16576	Gene names	RBBP7, RBAP46
Domain Architecture
Description	Histone-binding protein RBBP7 (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46) (Histone acetyltransferase type B subunit 2) (Nucleosome remodeling factor subunit RBAP46).

RBBP7_MOUSE
NC score	0.501129 (rank : 179)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	414	Target Neighborhood Hits	285	Shared Neighborhood Hits	230
SwissProt Accessions	Q60973, Q3UX20	Gene names	Rbbp7, Rbap46
Domain Architecture
Description	Histone-binding protein RBBP7 (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46) (Histone acetyltransferase type B subunit 2) (Nucleosome remodeling factor subunit RBAP46).

STTP1_HUMAN
NC score	0.500816 (rank : 180)	θ value	2.44474e-05 (rank : 67)
Query Neighborhood Hits	414	Target Neighborhood Hits	232	Shared Neighborhood Hits	203
SwissProt Accessions	Q6IA86, Q53GZ0, Q687Y8, Q8N5C2, Q96GV4, Q96PI7, Q9H9N0, Q9NV81	Gene names	STATIP1
Domain Architecture	No domain graphic available
Description	Stat3-interacting protein (StIP1) (SHINC-2).

BOP1_HUMAN
NC score	0.492809 (rank : 181)	θ value	0.00175202 (rank : 115)
Query Neighborhood Hits	414	Target Neighborhood Hits	257	Shared Neighborhood Hits	202
SwissProt Accessions	Q14137, Q969Z6, Q96IS8, Q9BSA7, Q9BVM0	Gene names	BOP1, KIAA0124
Domain Architecture
Description	Ribosome biogenesis protein BOP1 (Block of proliferation 1 protein).

WDR79_MOUSE
NC score	0.490729 (rank : 182)	θ value	4.03905 (rank : 348)
Query Neighborhood Hits	414	Target Neighborhood Hits	216	Shared Neighborhood Hits	176
SwissProt Accessions	Q8VC51	Gene names	Wdr79
Domain Architecture	No domain graphic available
Description	WD repeat protein 79.

CORO7_HUMAN
NC score	0.490586 (rank : 183)	θ value	0.00390308 (rank : 135)
Query Neighborhood Hits	414	Target Neighborhood Hits	315	Shared Neighborhood Hits	230
SwissProt Accessions	P57737	Gene names	CORO7
Domain Architecture
Description	Coronin-7 (70 kDa WD repeat tumor rejection antigen homolog).

EMAL1_HUMAN
NC score	0.489506 (rank : 184)	θ value	7.1131e-05 (rank : 73)
Query Neighborhood Hits	414	Target Neighborhood Hits	214	Shared Neighborhood Hits	190
SwissProt Accessions	O00423	Gene names	EML1, EMAP1, EMAPL, EMAPL1
Domain Architecture
Description	Echinoderm microtubule-associated protein-like 1 (EMAP-1) (HuEMAP-1).

STTP1_MOUSE
NC score	0.487297 (rank : 185)	θ value	0.365318 (rank : 244)
Query Neighborhood Hits	414	Target Neighborhood Hits	246	Shared Neighborhood Hits	212
SwissProt Accessions	Q91WG4, Q3TIH5, Q3TIT0, Q8CBW6, Q9ESY7	Gene names	Statip1
Domain Architecture	No domain graphic available
Description	Stat3-interacting protein (StIP1).

WDR43_HUMAN
NC score	0.486797 (rank : 186)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	414	Target Neighborhood Hits	269	Shared Neighborhood Hits	169
SwissProt Accessions	Q15061, Q15395, Q92577	Gene names	WDR43, KIAA0007
Domain Architecture	No domain graphic available
Description	WD repeat protein 43.

GNB1L_HUMAN
NC score	0.480780 (rank : 187)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	414	Target Neighborhood Hits	221	Shared Neighborhood Hits	181
SwissProt Accessions	Q9BYB4, Q9H2S2, Q9H4M4	Gene names	GNB1L, GY2, KIAA1645, WDR14
Domain Architecture
Description	Guanine nucleotide-binding protein subunit beta-like protein 1 (G protein subunit beta-like protein 1) (WD40 repeat-containing protein deleted in VCFS) (Protein WDVCF) (DGCRK3).

EMAL2_HUMAN
NC score	0.480501 (rank : 188)	θ value	4.03905 (rank : 337)
Query Neighborhood Hits	414	Target Neighborhood Hits	217	Shared Neighborhood Hits	188
SwissProt Accessions	O95834, Q9UG50	Gene names	EML2, EMAP2, EMAPL2
Domain Architecture
Description	Echinoderm microtubule-associated protein-like 2 (EMAP-2) (HuEMAP-2).

SEH1L_HUMAN
NC score	0.479491 (rank : 189)	θ value	0.0252991 (rank : 164)
Query Neighborhood Hits	414	Target Neighborhood Hits	145	Shared Neighborhood Hits	134
SwissProt Accessions	Q96EE3, Q8NFU6, Q96MH3, Q9C069	Gene names	SEH1L, SEC13L, SEH1
Domain Architecture
Description	Nucleoporin SEH1-like (SEC13-like protein).

IFT80_MOUSE
NC score	0.476273 (rank : 190)	θ value	0.00134147 (rank : 112)
Query Neighborhood Hits	414	Target Neighborhood Hits	200	Shared Neighborhood Hits	179
SwissProt Accessions	Q8K057	Gene names	Ift80, Wdr56
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 80 homolog (WD repeat protein 56).

WDR13_HUMAN
NC score	0.475347 (rank : 191)	θ value	0.0252991 (rank : 165)
Query Neighborhood Hits	414	Target Neighborhood Hits	186	Shared Neighborhood Hits	168
SwissProt Accessions	Q9H1Z4, Q9BUL7, Q9NWW4	Gene names	WDR13
Domain Architecture
Description	WD repeat protein 13.

EMAL4_HUMAN
NC score	0.473248 (rank : 192)	θ value	0.279714 (rank : 232)
Query Neighborhood Hits	414	Target Neighborhood Hits	306	Shared Neighborhood Hits	201
SwissProt Accessions	Q9HC35	Gene names	EML4, C2orf2, EMAPL4
Domain Architecture
Description	Echinoderm microtubule-associated protein-like 4 (EMAP-4) (Restrictedly overexpressed proliferation-associated protein) (Ropp 120).

WDR13_MOUSE
NC score	0.469459 (rank : 193)	θ value	0.0252991 (rank : 166)
Query Neighborhood Hits	414	Target Neighborhood Hits	195	Shared Neighborhood Hits	177
SwissProt Accessions	Q91V09	Gene names	Wdr13
Domain Architecture
Description	WD repeat protein 13.

IFT80_HUMAN
NC score	0.466350 (rank : 194)	θ value	0.00228821 (rank : 124)
Query Neighborhood Hits	414	Target Neighborhood Hits	195	Shared Neighborhood Hits	175
SwissProt Accessions	Q9P2H3	Gene names	IFT80, KIAA1374, WDR56
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 80 homolog (WD repeat protein 56).

WDR79_HUMAN
NC score	0.464445 (rank : 195)	θ value	2.36792 (rank : 324)
Query Neighborhood Hits	414	Target Neighborhood Hits	246	Shared Neighborhood Hits	170
SwissProt Accessions	Q9BUR4, Q9NW09	Gene names	WDR79
Domain Architecture	No domain graphic available
Description	WD repeat protein 79.

RFWD2_HUMAN
NC score	0.457947 (rank : 196)	θ value	6.88961 (rank : 378)
Query Neighborhood Hits	414	Target Neighborhood Hits	518	Shared Neighborhood Hits	204
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

BUB3_HUMAN
NC score	0.457893 (rank : 197)	θ value	1.81305 (rank : 302)
Query Neighborhood Hits	414	Target Neighborhood Hits	200	Shared Neighborhood Hits	169
SwissProt Accessions	O43684, O43685	Gene names	BUB3
Domain Architecture
Description	Mitotic checkpoint protein BUB3.

THOC6_HUMAN
NC score	0.457864 (rank : 198)	θ value	0.813845 (rank : 275)
Query Neighborhood Hits	414	Target Neighborhood Hits	223	Shared Neighborhood Hits	183
SwissProt Accessions	Q86W42, Q8NBR1, Q9BTV9	Gene names	THOC6, WDR58
Domain Architecture	No domain graphic available
Description	THO complex subunit 6 homolog (WD repeat protein 58).

RFWD2_MOUSE
NC score	0.456794 (rank : 199)	θ value	6.88961 (rank : 379)
Query Neighborhood Hits	414	Target Neighborhood Hits	535	Shared Neighborhood Hits	203
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

WDFY2_HUMAN
NC score	0.456720 (rank : 200)	θ value	0.279714 (rank : 236)
Query Neighborhood Hits	414	Target Neighborhood Hits	332	Shared Neighborhood Hits	230
SwissProt Accessions	Q96P53, Q96CS1	Gene names	WDFY2, WDF2, ZFYVE22
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2) (Zinc finger FYVE domain-containing protein 22).

WDFY2_MOUSE
NC score	0.450647 (rank : 201)	θ value	0.62314 (rank : 265)
Query Neighborhood Hits	414	Target Neighborhood Hits	337	Shared Neighborhood Hits	232
SwissProt Accessions	Q8BUB4	Gene names	Wdfy2
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2).

SCAP_HUMAN
NC score	0.450408 (rank : 202)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	414	Target Neighborhood Hits	368	Shared Neighborhood Hits	183
SwissProt Accessions	Q12770, Q8N2E0, Q8WUA1	Gene names	SCAP, KIAA0199
Domain Architecture
Description	Sterol regulatory element-binding protein cleavage-activating protein (SREBP cleavage-activating protein) (SCAP).

WDR75_HUMAN
NC score	0.449463 (rank : 203)	θ value	0.163984 (rank : 226)
Query Neighborhood Hits	414	Target Neighborhood Hits	193	Shared Neighborhood Hits	153
SwissProt Accessions	Q8IWA0, Q96J10, Q9H8U8, Q9H9U5, Q9H9V8, Q9UIX2	Gene names	WDR75
Domain Architecture	No domain graphic available
Description	WD repeat protein 75.

BUB3_MOUSE
NC score	0.448055 (rank : 204)	θ value	1.81305 (rank : 303)
Query Neighborhood Hits	414	Target Neighborhood Hits	199	Shared Neighborhood Hits	169
SwissProt Accessions	Q9WVA3, P97397	Gene names	Bub3
Domain Architecture
Description	Mitotic checkpoint protein BUB3 (WD repeat type I transmembrane protein A72.5).

WDFY1_HUMAN
NC score	0.446045 (rank : 205)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	414	Target Neighborhood Hits	305	Shared Neighborhood Hits	218
SwissProt Accessions	Q8IWB7, Q9H9D5, Q9P2B3	Gene names	WDFY1, KIAA1435, WDF1, ZFYVE17
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 1 (WD40- and FYVE domain- containing protein 1) (Phosphoinositide-binding protein 1) (FENS-1) (Zinc finger FYVE domain-containing protein 17).

DDB2_HUMAN
NC score	0.436468 (rank : 206)	θ value	0.00390308 (rank : 136)
Query Neighborhood Hits	414	Target Neighborhood Hits	175	Shared Neighborhood Hits	152
SwissProt Accessions	Q92466, Q76E54, Q76E55, Q76E56, Q76E57	Gene names	DDB2
Domain Architecture
Description	DNA damage-binding protein 2 (Damage-specific DNA-binding protein 2) (DDB p48 subunit) (DDBb) (UV-damaged DNA-binding protein 2) (UV-DDB 2).

FBXW9_HUMAN
NC score	0.432649 (rank : 207)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	414	Target Neighborhood Hits	184	Shared Neighborhood Hits	145
SwissProt Accessions	Q5XUX1, Q9BT89	Gene names	FBXW9, FBW9
Domain Architecture	No domain graphic available
Description	F-box/WD repeat protein 9 (F-box and WD-40 domain protein 9).

NUP37_MOUSE
NC score	0.430040 (rank : 208)	θ value	0.163984 (rank : 223)
Query Neighborhood Hits	414	Target Neighborhood Hits	159	Shared Neighborhood Hits	149
SwissProt Accessions	Q9CWU9	Gene names	Nup37
Domain Architecture
Description	Nucleoporin Nup37.

CORO6_MOUSE
NC score	0.427514 (rank : 209)	θ value	0.00228821 (rank : 122)
Query Neighborhood Hits	414	Target Neighborhood Hits	246	Shared Neighborhood Hits	201
SwissProt Accessions	Q920M5, Q920M3, Q920M4	Gene names	Coro6
Domain Architecture	No domain graphic available
Description	Coronin-6 (Clipin E).

ZF106_HUMAN
NC score	0.426485 (rank : 210)	θ value	3.0926 (rank : 331)
Query Neighborhood Hits	414	Target Neighborhood Hits	470	Shared Neighborhood Hits	189
SwissProt Accessions	Q9H2Y7, Q6NSD9, Q6PEK1, Q86T43, Q86T45, Q86T50, Q86T58, Q86TA9, Q96M37, Q9H7B8	Gene names	ZFP106, ZNF474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 homolog (Zfp-106) (Zinc finger protein 474).

WDTC1_HUMAN
NC score	0.419561 (rank : 211)	θ value	8.99809 (rank : 413)
Query Neighborhood Hits	414	Target Neighborhood Hits	299	Shared Neighborhood Hits	211
SwissProt Accessions	Q8N5D0, Q9NV87, Q9UPW4	Gene names	WDTC1, KIAA1037
Domain Architecture
Description	WD and tetratricopeptide repeats protein 1.

WDTC1_MOUSE
NC score	0.418030 (rank : 212)	θ value	8.99809 (rank : 414)
Query Neighborhood Hits	414	Target Neighborhood Hits	298	Shared Neighborhood Hits	211
SwissProt Accessions	Q80ZK9	Gene names	Wdtc1
Domain Architecture
Description	WD and tetratricopeptide repeats protein 1.

ZF106_MOUSE
NC score	0.413604 (rank : 213)	θ value	4.03905 (rank : 350)
Query Neighborhood Hits	414	Target Neighborhood Hits	472	Shared Neighborhood Hits	190
SwissProt Accessions	O88466, O55185, O88465, O88467, Q792M1, Q792P4, Q8CDZ8, Q8R3I4, Q9ESU3	Gene names	Zfp106, H3a, Sh3bp3, Sirm, Znf474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 (Zfp-106) (Zinc finger protein 474) (H3a minor histocompatibility antigen) (Son of insulin receptor mutant).

NUP37_HUMAN
NC score	0.412612 (rank : 214)	θ value	0.0736092 (rank : 196)
Query Neighborhood Hits	414	Target Neighborhood Hits	153	Shared Neighborhood Hits	140
SwissProt Accessions	Q8NFH4, Q9H644	Gene names	NUP37
Domain Architecture
Description	Nucleoporin Nup37 (p37).

AAAS_HUMAN
NC score	0.412470 (rank : 215)	θ value	0.00035302 (rank : 98)
Query Neighborhood Hits	414	Target Neighborhood Hits	154	Shared Neighborhood Hits	135
SwissProt Accessions	Q9NRG9, Q9NWI6, Q9UG19	Gene names	AAAS, ADRACALA
Domain Architecture
Description	Aladin (Adracalin).

WDR20_MOUSE
NC score	0.406520 (rank : 216)	θ value	5.27518 (rank : 363)
Query Neighborhood Hits	414	Target Neighborhood Hits	217	Shared Neighborhood Hits	177
SwissProt Accessions	Q9D5R2	Gene names	Wdr20
Domain Architecture
Description	WD repeat protein 20.

DDB2_MOUSE
NC score	0.401810 (rank : 217)	θ value	0.0563607 (rank : 186)
Query Neighborhood Hits	414	Target Neighborhood Hits	175	Shared Neighborhood Hits	156
SwissProt Accessions	Q99J79	Gene names	Ddb2
Domain Architecture	No domain graphic available
Description	DNA damage-binding protein 2 (Damage-specific DNA-binding protein 2).

WDR41_MOUSE
NC score	0.398215 (rank : 218)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	414	Target Neighborhood Hits	209	Shared Neighborhood Hits	172
SwissProt Accessions	Q3UDP0, Q8C4F1, Q8C8K5	Gene names	Wdr41
Domain Architecture	No domain graphic available
Description	WD repeat protein 41.

THOC6_MOUSE
NC score	0.397893 (rank : 219)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	414	Target Neighborhood Hits	199	Shared Neighborhood Hits	165
SwissProt Accessions	Q5U4D9	Gene names	Thoc6, Wdr58
Domain Architecture	No domain graphic available
Description	THO complex subunit 6 homolog (WD repeat protein 58).

WDR20_HUMAN
NC score	0.397891 (rank : 220)	θ value	3.0926 (rank : 330)
Query Neighborhood Hits	414	Target Neighborhood Hits	249	Shared Neighborhood Hits	185
SwissProt Accessions	Q8TBZ3, Q8WXX2, Q9UF86	Gene names	WDR20
Domain Architecture
Description	WD repeat protein 20 (DMR protein).

DMWD_MOUSE
NC score	0.397666 (rank : 221)	θ value	8.99809 (rank : 397)
Query Neighborhood Hits	414	Target Neighborhood Hits	282	Shared Neighborhood Hits	178
SwissProt Accessions	Q08274	Gene names	Dmwd, Dm9
Domain Architecture
Description	Dystrophia myotonica WD repeat-containing protein (Dystrophia myotonica-containing WD repeat motif protein) (DMR-N9 protein).

COR1C_HUMAN
NC score	0.397249 (rank : 222)	θ value	0.00869519 (rank : 146)
Query Neighborhood Hits	414	Target Neighborhood Hits	246	Shared Neighborhood Hits	204
SwissProt Accessions	Q9ULV4, Q9NSK5	Gene names	CORO1C, CRNN4
Domain Architecture
Description	Coronin-1C (Coronin-3) (hCRNN4).

COR1C_MOUSE
NC score	0.396968 (rank : 223)	θ value	0.0148317 (rank : 158)
Query Neighborhood Hits	414	Target Neighborhood Hits	251	Shared Neighborhood Hits	205
SwissProt Accessions	Q9WUM4, Q8VCQ5	Gene names	Coro1c
Domain Architecture
Description	Coronin-1C (Coronin-3).

WDR6_HUMAN
NC score	0.394392 (rank : 224)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	414	Target Neighborhood Hits	193	Shared Neighborhood Hits	155
SwissProt Accessions	Q9NNW5, Q9UF63	Gene names	WDR6
Domain Architecture
Description	WD repeat protein 6.

DMXL2_HUMAN
NC score	0.393514 (rank : 225)	θ value	0.0193708 (rank : 161)
Query Neighborhood Hits	414	Target Neighborhood Hits	374	Shared Neighborhood Hits	193
SwissProt Accessions	Q8TDJ6, O94938	Gene names	DMXL2, KIAA0856
Domain Architecture	No domain graphic available
Description	Protein DmX-like 2 (Rabconnectin-3).

COR2B_MOUSE
NC score	0.393471 (rank : 226)	θ value	5.27518 (rank : 354)
Query Neighborhood Hits	414	Target Neighborhood Hits	235	Shared Neighborhood Hits	196
SwissProt Accessions	Q8BH44, Q6P5U9	Gene names	Coro2b
Domain Architecture	No domain graphic available
Description	Coronin-2B.

COR1A_HUMAN
NC score	0.392933 (rank : 227)	θ value	0.21417 (rank : 227)
Query Neighborhood Hits	414	Target Neighborhood Hits	240	Shared Neighborhood Hits	196
SwissProt Accessions	P31146	Gene names	CORO1A, CORO1
Domain Architecture
Description	Coronin-1A (Coronin-like protein p57) (Coronin-like protein A) (CLIPINA) (Tryptophan aspartate-containing coat protein) (TACO).

COR1A_MOUSE
NC score	0.391889 (rank : 228)	θ value	6.88961 (rank : 367)
Query Neighborhood Hits	414	Target Neighborhood Hits	243	Shared Neighborhood Hits	192
SwissProt Accessions	O89053, Q7TMU0, Q9R1Y8, Q9R288	Gene names	Coro1a, Coro1
Domain Architecture
Description	Coronin-1A (Coronin-like protein p57) (Coronin-like protein A) (CLIPINA) (Tryptophan aspartate-containing coat protein) (TACO).

COR2B_HUMAN
NC score	0.388830 (rank : 229)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	414	Target Neighborhood Hits	233	Shared Neighborhood Hits	194
SwissProt Accessions	Q9UQ03, O94767, Q8TAN1	Gene names	CORO2B, KIAA0925
Domain Architecture
Description	Coronin-2B (Coronin-like protein C) (ClipinC) (Protein FC96).

DMXL1_MOUSE
NC score	0.385712 (rank : 230)	θ value	0.000121331 (rank : 79)
Query Neighborhood Hits	414	Target Neighborhood Hits	257	Shared Neighborhood Hits	179
SwissProt Accessions	Q6PNC0, Q3TLG8, Q6PHM6, Q8BQF2	Gene names	Dmxl1
Domain Architecture	No domain graphic available
Description	Protein DmX-like 1 (X-like 1 protein).

WDR24_HUMAN
NC score	0.384140 (rank : 231)	θ value	6.88961 (rank : 389)
Query Neighborhood Hits	414	Target Neighborhood Hits	247	Shared Neighborhood Hits	190
SwissProt Accessions	Q96S15, Q96GC7, Q9H0B7	Gene names	WDR24
Domain Architecture	No domain graphic available
Description	WD repeat protein 24.

COR2A_HUMAN
NC score	0.381355 (rank : 232)	θ value	0.0431538 (rank : 182)
Query Neighborhood Hits	414	Target Neighborhood Hits	214	Shared Neighborhood Hits	183
SwissProt Accessions	Q92828, Q92829, Q9BWS5	Gene names	CORO2A, IR10, WDR2
Domain Architecture
Description	Coronin-2A (WD repeat-containing protein 2) (IR10).

WDR7_MOUSE
NC score	0.376598 (rank : 233)	θ value	0.47712 (rank : 257)
Query Neighborhood Hits	414	Target Neighborhood Hits	226	Shared Neighborhood Hits	176
SwissProt Accessions	Q920I9, Q80TY3, Q920J0	Gene names	Wdr7, Kiaa0541, Trag
Domain Architecture	No domain graphic available
Description	WD repeat protein 7 (TGF-beta resistance-associated protein TRAG).

CIR1A_HUMAN
NC score	0.376372 (rank : 234)	θ value	0.00509761 (rank : 137)
Query Neighborhood Hits	414	Target Neighborhood Hits	158	Shared Neighborhood Hits	138
SwissProt Accessions	Q969X6, Q8NCD9, Q8TF14, Q96SP0, Q96SR9, Q96SZ9, Q96T13, Q9BWK6	Gene names	CIRH1A, KIAA1988
Domain Architecture
Description	Cirhin.

TLE4_MOUSE
NC score	0.376019 (rank : 235)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	414	Target Neighborhood Hits	482	Shared Neighborhood Hits	223
SwissProt Accessions	Q62441, Q9JKQ9	Gene names	Tle4, Grg4
Domain Architecture
Description	Transducin-like enhancer protein 4 (Groucho-related protein 4) (Grg- 4).

TLE4_HUMAN
NC score	0.375926 (rank : 236)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	414	Target Neighborhood Hits	477	Shared Neighborhood Hits	222
SwissProt Accessions	Q04727, Q5T1Y2, Q9BZ07, Q9BZ08, Q9BZ09, Q9NSL3, Q9ULF9	Gene names	TLE4, KIAA1261
Domain Architecture
Description	Transducin-like enhancer protein 4.

FBXW4_MOUSE
NC score	0.374874 (rank : 237)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	414	Target Neighborhood Hits	205	Shared Neighborhood Hits	154
SwissProt Accessions	Q9JMJ2, Q9QXW3	Gene names	Fbxw4, Fbw4
Domain Architecture
Description	F-box/WD repeat protein 4 (F-box and WD-40 domain protein 4) (Hagoromo protein).

COR1B_MOUSE
NC score	0.373673 (rank : 238)	θ value	0.125558 (rank : 206)
Query Neighborhood Hits	414	Target Neighborhood Hits	235	Shared Neighborhood Hits	191
SwissProt Accessions	Q9WUM3, Q3UEB1, Q9CVA2	Gene names	Coro1b
Domain Architecture
Description	Coronin-1B (Coronin-2).

TLE3_MOUSE
NC score	0.372826 (rank : 239)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	414	Target Neighborhood Hits	378	Shared Neighborhood Hits	216
SwissProt Accessions	Q08122, Q923A4	Gene names	Tle3, Esg
Domain Architecture
Description	Transducin-like enhancer protein 3 (ESG) (Grg-3).

TLE2_HUMAN
NC score	0.372058 (rank : 240)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	414	Target Neighborhood Hits	321	Shared Neighborhood Hits	215
SwissProt Accessions	Q04725, Q8WVY0, Q9Y6S0	Gene names	TLE2
Domain Architecture
Description	Transducin-like enhancer protein 2 (ESG2).

TLE2_MOUSE
NC score	0.371654 (rank : 241)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	414	Target Neighborhood Hits	294	Shared Neighborhood Hits	213
SwissProt Accessions	Q9WVB2	Gene names	Tle2, Grg2
Domain Architecture
Description	Transducin-like enhancer protein 2.

COR1B_HUMAN
NC score	0.370720 (rank : 242)	θ value	8.99809 (rank : 396)
Query Neighborhood Hits	414	Target Neighborhood Hits	239	Shared Neighborhood Hits	195
SwissProt Accessions	Q9BR76	Gene names	CORO1B
Domain Architecture
Description	Coronin-1B (Coronin-2).

TLE3_HUMAN
NC score	0.370537 (rank : 243)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	414	Target Neighborhood Hits	385	Shared Neighborhood Hits	216
SwissProt Accessions	Q04726, Q8IVV6, Q8WVR2, Q9HCM5	Gene names	TLE3, KIAA1547
Domain Architecture
Description	Transducin-like enhancer protein 3 (ESG3).

WDR41_HUMAN
NC score	0.370385 (rank : 244)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	414	Target Neighborhood Hits	208	Shared Neighborhood Hits	177
SwissProt Accessions	Q9HAD4, Q7Z792, Q8IWG3, Q8IXA9, Q8NDA7, Q9NV62	Gene names	WDR41
Domain Architecture	No domain graphic available
Description	WD repeat protein 41.

AAAS_MOUSE
NC score	0.368534 (rank : 245)	θ value	0.00175202 (rank : 114)
Query Neighborhood Hits	414	Target Neighborhood Hits	144	Shared Neighborhood Hits	123
SwissProt Accessions	P58742, Q544M6	Gene names	Aaas
Domain Architecture
Description	Aladin (Adracalin).

COR2A_MOUSE
NC score	0.366967 (rank : 246)	θ value	0.0736092 (rank : 193)
Query Neighborhood Hits	414	Target Neighborhood Hits	204	Shared Neighborhood Hits	174
SwissProt Accessions	Q8C0P5, Q3U6H8, Q8BW42	Gene names	Coro2a
Domain Architecture	No domain graphic available
Description	Coronin-2A.

TLE1_MOUSE
NC score	0.364327 (rank : 247)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	414	Target Neighborhood Hits	491	Shared Neighborhood Hits	217
SwissProt Accessions	Q62440	Gene names	Tle1, Grg1
Domain Architecture
Description	Transducin-like enhancer protein 1 (Groucho-related protein 1) (Grg- 1).

TLE1_HUMAN
NC score	0.364226 (rank : 248)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	414	Target Neighborhood Hits	485	Shared Neighborhood Hits	215
SwissProt Accessions	Q04724, Q5T3G4, Q969V9	Gene names	TLE1
Domain Architecture
Description	Transducin-like enhancer protein 1 (ESG1) (E(Sp1) homolog).

WDR7_HUMAN
NC score	0.363338 (rank : 249)	θ value	0.813845 (rank : 277)
Query Neighborhood Hits	414	Target Neighborhood Hits	244	Shared Neighborhood Hits	176
SwissProt Accessions	Q9Y4E6, Q86UX5, Q86VP2, Q96PS7	Gene names	WDR7, KIAA0541, TRAG
Domain Architecture	No domain graphic available
Description	WD repeat protein 7 (TGF-beta resistance-associated protein TRAG) (Rabconnectin-3 beta).

FBXW4_HUMAN
NC score	0.355592 (rank : 250)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	414	Target Neighborhood Hits	209	Shared Neighborhood Hits	151
SwissProt Accessions	P57775, Q5SVS1, Q96IM6	Gene names	FBXW4, FBW4, SHFM3
Domain Architecture
Description	F-box/WD repeat protein 4 (F-box and WD-40 domain protein 4) (Dactylin).

DMXL1_HUMAN
NC score	0.355358 (rank : 251)	θ value	0.000158464 (rank : 84)
Query Neighborhood Hits	414	Target Neighborhood Hits	259	Shared Neighborhood Hits	177
SwissProt Accessions	Q9Y485	Gene names	DMXL1, XL1
Domain Architecture	No domain graphic available
Description	Protein DmX-like 1 (X-like 1 protein).

CIR1A_MOUSE
NC score	0.353269 (rank : 252)	θ value	1.38821 (rank : 297)
Query Neighborhood Hits	414	Target Neighborhood Hits	155	Shared Neighborhood Hits	138
SwissProt Accessions	Q8R2N2, Q62306, Q69Z48, Q6NVG9, Q8VEL5	Gene names	Cirh1a, Kiaa1988, Tex292
Domain Architecture	No domain graphic available
Description	Cirhin (Testis-expressed gene 292 protein).

WD21C_HUMAN
NC score	0.340864 (rank : 253)	θ value	5.27518 (rank : 362)
Query Neighborhood Hits	414	Target Neighborhood Hits	157	Shared Neighborhood Hits	133
SwissProt Accessions	Q8NA75	Gene names	WDR21C
Domain Architecture	No domain graphic available
Description	WD repeat protein 21C.

PREB_HUMAN
NC score	0.330657 (rank : 254)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	414	Target Neighborhood Hits	163	Shared Neighborhood Hits	139
SwissProt Accessions	Q9HCU5, Q9UH94	Gene names	PREB, SEC12
Domain Architecture
Description	Prolactin regulatory element-binding protein (Mammalian guanine nucleotide exchange factor mSec12).

NUP43_HUMAN
NC score	0.318349 (rank : 255)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	414	Target Neighborhood Hits	198	Shared Neighborhood Hits	157
SwissProt Accessions	Q8NFH3, Q9H8S0	Gene names	NUP43
Domain Architecture
Description	Nucleoporin Nup43 (p42).

NUP43_MOUSE
NC score	0.318269 (rank : 256)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	414	Target Neighborhood Hits	193	Shared Neighborhood Hits	151
SwissProt Accessions	P59235	Gene names	Nup43
Domain Architecture
Description	Nucleoporin Nup43.

FBXW5_MOUSE
NC score	0.317203 (rank : 257)	θ value	0.62314 (rank : 260)
Query Neighborhood Hits	414	Target Neighborhood Hits	159	Shared Neighborhood Hits	127
SwissProt Accessions	Q9QXW2	Gene names	Fbxw5, Fbw5
Domain Architecture
Description	F-box/WD repeat protein 5 (F-box and WD-40 domain protein 5).

WDR81_MOUSE
NC score	0.316617 (rank : 258)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	414	Target Neighborhood Hits	228	Shared Neighborhood Hits	159
SwissProt Accessions	Q5ND34, Q3TA90, Q3TUS9, Q6KAR1	Gene names	Wdr81
Domain Architecture	No domain graphic available
Description	WD repeat protein 81.

ARC1B_HUMAN
NC score	0.311017 (rank : 259)	θ value	0.813845 (rank : 268)
Query Neighborhood Hits	414	Target Neighborhood Hits	148	Shared Neighborhood Hits	138
SwissProt Accessions	O15143, Q9BU00	Gene names	ARPC1B, ARC41
Domain Architecture
Description	Actin-related protein 2/3 complex subunit 1B (ARP2/3 complex 41 kDa subunit) (p41-ARC).

FBXW5_HUMAN
NC score	0.306630 (rank : 260)	θ value	0.813845 (rank : 270)
Query Neighborhood Hits	414	Target Neighborhood Hits	156	Shared Neighborhood Hits	126
SwissProt Accessions	Q969U6, Q5SPZ8, Q5SPZ9, Q5SQ02, Q5SQ03, Q5SQ04, Q8WY79, Q96GJ6, Q9BSU8, Q9H6A8, Q9HBQ6, Q9NSZ3	Gene names	FBXW5, FBW5
Domain Architecture
Description	F-box/WD repeat protein 5 (F-box and WD-40 domain protein 5).

UTP18_HUMAN
NC score	0.301786 (rank : 261)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	414	Target Neighborhood Hits	139	Shared Neighborhood Hits	109
SwissProt Accessions	Q9Y5J1, Q9H4N6	Gene names	UTP18, WDR50
Domain Architecture
Description	U3 small nucleolar RNA-associated protein 18 homolog (WD repeat protein 50).

PREB_MOUSE
NC score	0.298909 (rank : 262)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	414	Target Neighborhood Hits	156	Shared Neighborhood Hits	132
SwissProt Accessions	Q9WUQ2, Q9QZ99	Gene names	Preb, Sec12
Domain Architecture
Description	Prolactin regulatory element-binding protein (Mammalian guanine nucleotide exchange factor mSec12).

WDR72_HUMAN
NC score	0.297116 (rank : 263)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	414	Target Neighborhood Hits	167	Shared Neighborhood Hits	135
SwissProt Accessions	Q3MJ13, Q7Z3I3, Q8N8X2	Gene names	WDR72
Domain Architecture	No domain graphic available
Description	WD repeat protein 72.

ARC1A_HUMAN
NC score	0.297067 (rank : 264)	θ value	0.000786445 (rank : 107)
Query Neighborhood Hits	414	Target Neighborhood Hits	113	Shared Neighborhood Hits	108
SwissProt Accessions	Q92747, Q7Z5U8, Q86WU5, Q8IXQ0	Gene names	ARPC1A, SOP2L
Domain Architecture
Description	Actin-related protein 2/3 complex subunit 1A (SOP2-like protein).

ARC1A_MOUSE
NC score	0.294981 (rank : 265)	θ value	0.00228821 (rank : 121)
Query Neighborhood Hits	414	Target Neighborhood Hits	120	Shared Neighborhood Hits	115
SwissProt Accessions	Q9R0Q6, Q3UL75	Gene names	Arpc1a, Sid329
Domain Architecture	No domain graphic available
Description	Actin-related protein 2/3 complex subunit 1A (SOP2-like protein) (Sid 329).

LYST_HUMAN
NC score	0.290855 (rank : 266)	θ value	0.365318 (rank : 240)
Query Neighborhood Hits	414	Target Neighborhood Hits	324	Shared Neighborhood Hits	161
SwissProt Accessions	Q99698, O43274, Q5T2U9, Q96TD7, Q96TD8, Q99709, Q9H133	Gene names	LYST, CHS, CHS1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige homolog).

ARC1B_MOUSE
NC score	0.288517 (rank : 267)	θ value	3.0926 (rank : 325)
Query Neighborhood Hits	414	Target Neighborhood Hits	133	Shared Neighborhood Hits	124
SwissProt Accessions	Q9WV32	Gene names	Arpc1b
Domain Architecture
Description	Actin-related protein 2/3 complex subunit 1B (ARP2/3 complex 41 kDa subunit) (p41-ARC).

WDR81_HUMAN
NC score	0.288038 (rank : 268)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	414	Target Neighborhood Hits	205	Shared Neighborhood Hits	151
SwissProt Accessions	Q562E7, Q24JP6, Q8N277, Q8N3F3	Gene names	WDR81
Domain Architecture	No domain graphic available
Description	WD repeat protein 81.

TSCC1_MOUSE
NC score	0.286870 (rank : 269)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	414	Target Neighborhood Hits	160	Shared Neighborhood Hits	128
SwissProt Accessions	Q8K0G5	Gene names	Tssc1
Domain Architecture	No domain graphic available
Description	Protein TSSC1.

RPTOR_HUMAN
NC score	0.283658 (rank : 270)	θ value	0.00175202 (rank : 117)
Query Neighborhood Hits	414	Target Neighborhood Hits	121	Shared Neighborhood Hits	91
SwissProt Accessions	Q8N122, Q8N4V9, Q8TB32, Q9P2P3	Gene names	RAPTOR, KIAA1303
Domain Architecture
Description	Regulatory-associated protein of mTOR (Raptor) (P150 target of rapamycin (TOR)-scaffold protein).

WDR4_MOUSE
NC score	0.279684 (rank : 271)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	414	Target Neighborhood Hits	136	Shared Neighborhood Hits	119
SwissProt Accessions	Q9EP82	Gene names	Wdr4
Domain Architecture
Description	WD repeat protein 4.

TSSC1_HUMAN
NC score	0.276748 (rank : 272)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	414	Target Neighborhood Hits	157	Shared Neighborhood Hits	130
SwissProt Accessions	Q53HC9, O43179, Q53S19, Q53SG2	Gene names	TSSC1
Domain Architecture	No domain graphic available
Description	Protein TSSC1 (Tumor-suppressing subchromosomal transferable fragment candidate gene 1 protein) (Tumor-suppressing STF cDNA 1 protein).

WDR4_HUMAN
NC score	0.276362 (rank : 273)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	414	Target Neighborhood Hits	145	Shared Neighborhood Hits	122
SwissProt Accessions	P57081, Q9HCR3	Gene names	WDR4
Domain Architecture
Description	WD repeat protein 4.

WD21A_HUMAN
NC score	0.271755 (rank : 274)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	414	Target Neighborhood Hits	136	Shared Neighborhood Hits	119
SwissProt Accessions	Q8WV16, Q86U31, Q96K22, Q9Y4P5	Gene names	WDR21A, WDR21
Domain Architecture
Description	WD repeat protein 21A.

LYST_MOUSE
NC score	0.269611 (rank : 275)	θ value	0.125558 (rank : 209)
Query Neighborhood Hits	414	Target Neighborhood Hits	286	Shared Neighborhood Hits	149
SwissProt Accessions	P97412, Q62403, Q8VBS6	Gene names	Lyst, Bg, Chs1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige protein) (CHS1 homolog).

RPTOR_MOUSE
NC score	0.264829 (rank : 276)	θ value	0.0113563 (rank : 153)
Query Neighborhood Hits	414	Target Neighborhood Hits	129	Shared Neighborhood Hits	93
SwissProt Accessions	Q8K4Q0, Q8C9W9, Q8CBY4, Q8CDY8, Q9D4H3	Gene names	Raptor
Domain Architecture
Description	Regulatory-associated protein of mTOR (Raptor) (P150 target of rapamycin (TOR)-scaffold protein).

KI21B_HUMAN
NC score	0.260940 (rank : 277)	θ value	0.62314 (rank : 262)
Query Neighborhood Hits	414	Target Neighborhood Hits	1017	Shared Neighborhood Hits	241
SwissProt Accessions	O75037, Q5T4J3	Gene names	KIF21B, KIAA0449
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B.

TLE6_MOUSE
NC score	0.257725 (rank : 278)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	414	Target Neighborhood Hits	178	Shared Neighborhood Hits	129
SwissProt Accessions	Q9WVB3	Gene names	Tle6, Grg6
Domain Architecture
Description	Transducin-like enhancer protein 6 (Groucho-related protein 6).

KI21B_MOUSE
NC score	0.256392 (rank : 279)	θ value	0.813845 (rank : 271)
Query Neighborhood Hits	414	Target Neighborhood Hits	997	Shared Neighborhood Hits	238
SwissProt Accessions	Q9QXL1, P97424	Gene names	Kif21b, Kif6
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B (Kinesin-like protein KIF6).

WDR67_MOUSE
NC score	0.252479 (rank : 280)	θ value	8.99809 (rank : 411)
Query Neighborhood Hits	414	Target Neighborhood Hits	476	Shared Neighborhood Hits	132
SwissProt Accessions	Q6NXY1, Q3TBW4, Q3U4F6, Q5KSA3, Q810J7, Q8C3Y2	Gene names	Wdr67
Domain Architecture	No domain graphic available
Description	WD repeat protein 67 (Protein 4-B-3).

WDFY3_MOUSE
NC score	0.249026 (rank : 281)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	414	Target Neighborhood Hits	332	Shared Neighborhood Hits	173
SwissProt Accessions	Q6VNB8, Q8C8H7	Gene names	Wdfy3
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Beach domain, WD repeat and FYVE domain-containing protein 1) (BWF1).

WDFY3_HUMAN
NC score	0.246446 (rank : 282)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	414	Target Neighborhood Hits	348	Shared Neighborhood Hits	174
SwissProt Accessions	Q8IZQ1, Q4W5K5, Q6P0Q5, Q8N1T2, Q96BS7, Q96N85, Q9Y2J7	Gene names	WDFY3, KIAA0993
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy).

UTP18_MOUSE
NC score	0.242083 (rank : 283)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	414	Target Neighborhood Hits	139	Shared Neighborhood Hits	98
SwissProt Accessions	Q5SSI6	Gene names	Utp18, Wdr50
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 18 homolog (WD repeat protein 50).

KI21A_HUMAN
NC score	0.236695 (rank : 284)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	414	Target Neighborhood Hits	1543	Shared Neighborhood Hits	260
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

FBXW8_HUMAN
NC score	0.234240 (rank : 285)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	414	Target Neighborhood Hits	192	Shared Neighborhood Hits	115
SwissProt Accessions	Q8N3Y1, Q9UK95	Gene names	FBXW8, FBW6, FBW8, FBX29, FBXO29, FBXW6
Domain Architecture
Description	F-box/WD repeat protein 8 (F-box and WD-40 domain protein 8) (F-box only protein 29).

KI21A_MOUSE
NC score	0.233367 (rank : 286)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	414	Target Neighborhood Hits	1317	Shared Neighborhood Hits	241
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

NBEAL_HUMAN
NC score	0.231639 (rank : 287)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	414	Target Neighborhood Hits	200	Shared Neighborhood Hits	148
SwissProt Accessions	Q6ZS30, Q6Y876, Q6ZQY5, Q96Q30	Gene names	NBEAL1, ALS2CR17
Domain Architecture	No domain graphic available
Description	Neurobeachin-like 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein).

WDR46_HUMAN
NC score	0.226956 (rank : 288)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	414	Target Neighborhood Hits	147	Shared Neighborhood Hits	102
SwissProt Accessions	O15213, Q5STK5	Gene names	WDR46, BING4, C6orf11
Domain Architecture
Description	WD repeat protein 46 (WD repeat protein BING4).

DC1I2_MOUSE
NC score	0.222174 (rank : 289)	θ value	0.279714 (rank : 230)
Query Neighborhood Hits	414	Target Neighborhood Hits	209	Shared Neighborhood Hits	131
SwissProt Accessions	O88487, Q3TGH7	Gene names	Dync1i2, Dnci2, Dncic2
Domain Architecture
Description	Cytoplasmic dynein 1 intermediate chain 2 (Dynein intermediate chain 2, cytosolic) (DH IC-2) (Cytoplasmic dynein intermediate chain 2).

DC1I2_HUMAN
NC score	0.218839 (rank : 290)	θ value	0.125558 (rank : 207)
Query Neighborhood Hits	414	Target Neighborhood Hits	201	Shared Neighborhood Hits	129
SwissProt Accessions	Q13409, Q96NG7, Q96S87, Q9BXZ5, Q9NT58	Gene names	DYNC1I2, DNCI2, DNCIC2
Domain Architecture
Description	Cytoplasmic dynein 1 intermediate chain 2 (Dynein intermediate chain 2, cytosolic) (DH IC-2) (Cytoplasmic dynein intermediate chain 2).

WDR67_HUMAN
NC score	0.216523 (rank : 291)	θ value	1.06291 (rank : 293)
Query Neighborhood Hits	414	Target Neighborhood Hits	782	Shared Neighborhood Hits	154
SwissProt Accessions	Q96DN5, Q3MIR6, Q8TBP9	Gene names	WDR67
Domain Architecture	No domain graphic available
Description	WD repeat protein 67.

DNAI1_HUMAN
NC score	0.210678 (rank : 292)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	414	Target Neighborhood Hits	148	Shared Neighborhood Hits	110
SwissProt Accessions	Q9UI46, Q9UEZ8	Gene names	DNAI1
Domain Architecture
Description	Dynein intermediate chain 1, axonemal (Axonemal dynein intermediate chain 1).

WDR35_HUMAN
NC score	0.210454 (rank : 293)	θ value	0.0113563 (rank : 156)
Query Neighborhood Hits	414	Target Neighborhood Hits	132	Shared Neighborhood Hits	106
SwissProt Accessions	Q9P2L0, Q8NE11	Gene names	WDR35, KIAA1336
Domain Architecture
Description	WD repeat protein 35.

WDR46_MOUSE
NC score	0.208065 (rank : 294)	θ value	5.27518 (rank : 364)
Query Neighborhood Hits	414	Target Neighborhood Hits	243	Shared Neighborhood Hits	103
SwissProt Accessions	Q9Z0H1	Gene names	Wdr46, Bing4
Domain Architecture
Description	WD repeat protein 46 (WD repeat protein BING4).

WDR85_HUMAN
NC score	0.205940 (rank : 295)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	414	Target Neighborhood Hits	134	Shared Neighborhood Hits	116
SwissProt Accessions	Q9BTV6, Q96AB7	Gene names	WDR85, C9orf112
Domain Architecture	No domain graphic available
Description	WD repeat protein 85.

WDR68_HUMAN
NC score	0.205397 (rank : 296)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	414	Target Neighborhood Hits	121	Shared Neighborhood Hits	107
SwissProt Accessions	P61962, O15491, Q9DAE4	Gene names	WDR68, HAN11
Domain Architecture
Description	WD repeat protein 68 (WD repeat protein An11 homolog).

WDR68_MOUSE
NC score	0.205397 (rank : 297)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	414	Target Neighborhood Hits	121	Shared Neighborhood Hits	107
SwissProt Accessions	P61963, O15491, Q3TMV9, Q9DAE4	Gene names	Wdr68, Han11
Domain Architecture
Description	WD repeat protein 68 (WD repeat protein An11 homolog).

FBXW8_MOUSE
NC score	0.202791 (rank : 298)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	414	Target Neighborhood Hits	162	Shared Neighborhood Hits	90
SwissProt Accessions	Q8BIA4, Q8BI62, Q8BI75, Q8BI76, Q8CID8, Q921Z1	Gene names	Fbxw8
Domain Architecture
Description	F-box/WD repeat protein 8 (F-box and WD-40 domain protein 8).

WDR19_MOUSE
NC score	0.199606 (rank : 299)	θ value	0.000270298 (rank : 96)
Query Neighborhood Hits	414	Target Neighborhood Hits	83	Shared Neighborhood Hits	56
SwissProt Accessions	Q3UGF1, Q6ZPK8, Q80VQ6, Q8C794, Q8K3R5	Gene names	Wdr19, Kiaa1638
Domain Architecture	No domain graphic available
Description	WD repeat protein 19.

WDR19_HUMAN
NC score	0.195661 (rank : 300)	θ value	0.000602161 (rank : 106)
Query Neighborhood Hits	414	Target Neighborhood Hits	88	Shared Neighborhood Hits	51
SwissProt Accessions	Q8NEZ3, Q8N5B4, Q9H5S0, Q9HCD4	Gene names	WDR19, KIAA1638
Domain Architecture	No domain graphic available
Description	WD repeat protein 19.

DNAI2_HUMAN
NC score	0.192263 (rank : 301)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	414	Target Neighborhood Hits	156	Shared Neighborhood Hits	101
SwissProt Accessions	Q9GZS0, Q9H179, Q9NT53	Gene names	DNAI2
Domain Architecture
Description	Dynein intermediate chain 2, axonemal (Axonemal dynein intermediate chain 2).

WDR35_MOUSE
NC score	0.189068 (rank : 302)	θ value	0.0563607 (rank : 191)
Query Neighborhood Hits	414	Target Neighborhood Hits	126	Shared Neighborhood Hits	100
SwissProt Accessions	Q8BND3, Q8CDL4	Gene names	Wdr35
Domain Architecture
Description	WD repeat protein 35.

WDR34_MOUSE
NC score	0.178154 (rank : 303)	θ value	0.125558 (rank : 215)
Query Neighborhood Hits	414	Target Neighborhood Hits	105	Shared Neighborhood Hits	83
SwissProt Accessions	Q5U4F6	Gene names	Wdr34
Domain Architecture	No domain graphic available
Description	WD repeat protein 34.

DC1I1_HUMAN
NC score	0.164795 (rank : 304)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	414	Target Neighborhood Hits	183	Shared Neighborhood Hits	104
SwissProt Accessions	O14576, Q9Y2X1	Gene names	DYNC1I1, DNCI1, DNCIC1
Domain Architecture
Description	Cytoplasmic dynein 1 intermediate chain 1 (Dynein intermediate chain 1, cytosolic) (DH IC-1) (Cytoplasmic dynein intermediate chain 1).

WDR74_HUMAN
NC score	0.161985 (rank : 305)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	414	Target Neighborhood Hits	94	Shared Neighborhood Hits	68
SwissProt Accessions	Q6RFH5, Q9BRC9, Q9H6X8, Q9NVY2	Gene names	WDR74, NSA1
Domain Architecture	No domain graphic available
Description	WD repeat protein 74 (NOP seven-associated protein 1).

DC1I1_MOUSE
NC score	0.159361 (rank : 306)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	414	Target Neighborhood Hits	206	Shared Neighborhood Hits	108
SwissProt Accessions	O88485, O88486	Gene names	Dync1i1, Dnci1, Dncic1
Domain Architecture
Description	Cytoplasmic dynein 1 intermediate chain 1 (Dynein intermediate chain 1, cytosolic) (DH IC-1) (Cytoplasmic dynein intermediate chain 1).

PI3R4_HUMAN
NC score	0.156319 (rank : 307)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	414	Target Neighborhood Hits	534	Shared Neighborhood Hits	135
SwissProt Accessions	Q99570	Gene names	PIK3R4
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 4 (EC 2.7.11.1) (PI3- kinase regulatory subunit 4) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein).

TR95_MOUSE
NC score	0.155363 (rank : 308)	θ value	0.163984 (rank : 225)
Query Neighborhood Hits	414	Target Neighborhood Hits	95	Shared Neighborhood Hits	76
SwissProt Accessions	Q6PGF3	Gene names	Thrap5
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein complex 95 kDa component (Trap95) (Thyroid hormone receptor-associated protein 5) (Vitamin D3 receptor-interacting protein complex component DRIP92).

STB5L_MOUSE
NC score	0.154862 (rank : 309)	θ value	0.00298849 (rank : 133)
Query Neighborhood Hits	414	Target Neighborhood Hits	138	Shared Neighborhood Hits	94
SwissProt Accessions	Q5DQR4, Q3TSM3, Q3UVG2, Q5DQR1, Q5DQR2, Q5DQR3, Q8BS52	Gene names	Stxbp5l, Llgl4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 5-like (Tomosyn-2) (Lethal(2) giant larvae protein homolog 4).

STB5L_HUMAN
NC score	0.154125 (rank : 310)	θ value	0.00298849 (rank : 132)
Query Neighborhood Hits	414	Target Neighborhood Hits	139	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Y2K9, Q4G1B4, Q6PIC3	Gene names	STXBP5L, KIAA1006, LLGL4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 5-like (Tomosyn-2) (Lethal(2) giant larvae protein homolog 4).

WDR34_HUMAN
NC score	0.152825 (rank : 311)	θ value	1.38821 (rank : 299)
Query Neighborhood Hits	414	Target Neighborhood Hits	100	Shared Neighborhood Hits	79
SwissProt Accessions	Q96EX3, Q5VXV4, Q9BV46	Gene names	WDR34
Domain Architecture
Description	WD repeat protein 34.

IF140_HUMAN
NC score	0.150303 (rank : 312)	θ value	5.27518 (rank : 357)
Query Neighborhood Hits	414	Target Neighborhood Hits	111	Shared Neighborhood Hits	77
SwissProt Accessions	Q96RY7, O60332	Gene names	IFT140, KIAA0590, WDTC2
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 140 homolog (WD and tetratricopeptide repeats protein 2).

TLE6_HUMAN
NC score	0.149265 (rank : 313)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	414	Target Neighborhood Hits	120	Shared Neighborhood Hits	80
SwissProt Accessions	Q9H808	Gene names	TLE6
Domain Architecture	No domain graphic available
Description	Transducin-like enhancer protein 6.

BRWD2_HUMAN
NC score	0.148581 (rank : 314)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	414	Target Neighborhood Hits	94	Shared Neighborhood Hits	75
SwissProt Accessions	Q9BZH6, Q5VWA1	Gene names	BRWD2, WDR11
Domain Architecture
Description	Bromodomain and WD repeat domain-containing protein 2 (WD repeat protein 11).

NBEA_HUMAN
NC score	0.146623 (rank : 315)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	414	Target Neighborhood Hits	186	Shared Neighborhood Hits	104
SwissProt Accessions	Q8NFP9, Q9HCM8, Q9NSU1, Q9NW98, Q9Y6J1	Gene names	NBEA, BCL8B, KIAA1544, LYST2
Domain Architecture
Description	Protein neurobeachin (Lysosomal-trafficking regulator 2) (Protein BCL8B).

NBEA_MOUSE
NC score	0.145985 (rank : 316)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	414	Target Neighborhood Hits	225	Shared Neighborhood Hits	106
SwissProt Accessions	Q9EPN1, Q8C931, Q9EPM9, Q9EPN0, Q9WVM9	Gene names	Nbea, Lyst2
Domain Architecture
Description	Protein neurobeachin (Lysosomal-trafficking regulator 2).

LRBA_HUMAN
NC score	0.144451 (rank : 317)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	414	Target Neighborhood Hits	196	Shared Neighborhood Hits	95
SwissProt Accessions	P50851, Q9H2U3, Q9H2U4	Gene names	LRBA, BGL, CDC4L, LBA
Domain Architecture
Description	Lipopolysaccharide-responsive and beige-like anchor protein (CDC4-like protein) (Beige-like protein).

WDR85_MOUSE
NC score	0.143420 (rank : 318)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	414	Target Neighborhood Hits	108	Shared Neighborhood Hits	87
SwissProt Accessions	Q9CYU6, Q5RJV7, Q8BIT9	Gene names	Wdr85
Domain Architecture	No domain graphic available
Description	WD repeat protein 85.

WDR8_MOUSE
NC score	0.141697 (rank : 319)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	414	Target Neighborhood Hits	71	Shared Neighborhood Hits	64
SwissProt Accessions	Q9JM98	Gene names	Wdr8, Dd57
Domain Architecture
Description	WD repeat protein 8.

WDR8_HUMAN
NC score	0.141240 (rank : 320)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	414	Target Neighborhood Hits	69	Shared Neighborhood Hits	62
SwissProt Accessions	Q9P2S5, Q5T0D6, Q9BUH7, Q9NTK7, Q9NX56	Gene names	WDR8
Domain Architecture
Description	WD repeat protein 8.

PI3R4_MOUSE
NC score	0.140775 (rank : 321)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	414	Target Neighborhood Hits	535	Shared Neighborhood Hits	129
SwissProt Accessions	Q8VD65, Q56A65, Q8C948, Q8C9D7, Q9CVC5	Gene names	Pik3r4
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 4 (EC 2.7.11.1) (PI3- kinase regulatory subunit 4).

TF3C2_MOUSE
NC score	0.136553 (rank : 322)	θ value	0.62314 (rank : 264)
Query Neighborhood Hits	414	Target Neighborhood Hits	165	Shared Neighborhood Hits	89
SwissProt Accessions	Q8BL74, Q3U7Z9, Q80XQ7, Q8BJJ4, Q8BLP3, Q8K1J1, Q9CSS0, Q9CVE6, Q9DBK6	Gene names	Gtf3c2, Kiaa0011
Domain Architecture
Description	General transcription factor 3C polypeptide 2 (Transcription factor IIIC-subunit beta) (TF3C-beta) (TFIIIC 110 kDa subunit) (TFIIIC110).

PPWD1_HUMAN
NC score	0.136534 (rank : 323)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	414	Target Neighborhood Hits	136	Shared Neighborhood Hits	98
SwissProt Accessions	Q96BP3, Q15002, Q7KZ89	Gene names	PPWD1, KIAA0073
Domain Architecture	No domain graphic available
Description	Peptidylprolyl isomerase domain and WD repeat-containing protein 1 (EC 5.2.1.8).

STXB5_HUMAN
NC score	0.133227 (rank : 324)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	414	Target Neighborhood Hits	167	Shared Neighborhood Hits	116
SwissProt Accessions	Q5T5C0, Q5T5C1, Q5T5C2, Q8NBG8, Q96NG9	Gene names	STXBP5, LLGL3
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 5 (Tomosyn-1) (Lethal(2) giant larvae protein homolog 3).

WDR74_MOUSE
NC score	0.132931 (rank : 325)	θ value	8.99809 (rank : 412)
Query Neighborhood Hits	414	Target Neighborhood Hits	70	Shared Neighborhood Hits	53
SwissProt Accessions	Q8VCG3	Gene names	Wdr74
Domain Architecture	No domain graphic available
Description	WD repeat protein 74.

TF3C2_HUMAN
NC score	0.131921 (rank : 326)	θ value	0.163984 (rank : 224)
Query Neighborhood Hits	414	Target Neighborhood Hits	168	Shared Neighborhood Hits	78
SwissProt Accessions	Q8WUA4, Q16632, Q9BWI7	Gene names	GTF3C2, KIAA0011
Domain Architecture
Description	General transcription factor 3C polypeptide 2 (Transcription factor IIIC-subunit beta) (TF3C-beta) (TFIIIC 110 kDa subunit) (TFIIIC110).

PPWD1_MOUSE
NC score	0.130515 (rank : 327)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	414	Target Neighborhood Hits	139	Shared Neighborhood Hits	95
SwissProt Accessions	Q8CEC6	Gene names	Ppwd1
Domain Architecture	No domain graphic available
Description	Peptidylprolyl isomerase domain and WD repeat-containing protein 1 (EC 5.2.1.8).

WDR54_MOUSE
NC score	0.128636 (rank : 328)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	414	Target Neighborhood Hits	96	Shared Neighborhood Hits	78
SwissProt Accessions	Q9R0D8, Q3U4A4	Gene names	Wdr54, D3Mm3e
Domain Architecture	No domain graphic available
Description	WD repeat protein 54.

STXB5_MOUSE
NC score	0.123616 (rank : 329)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	414	Target Neighborhood Hits	161	Shared Neighborhood Hits	110
SwissProt Accessions	Q8K400, Q80TM5, Q8K401, Q9D2F3	Gene names	Stxbp5, Kiaa4253, Llgl3
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 5 (Tomosyn-1) (Lethal(2) giant larvae protein homolog 3).

WIPI2_HUMAN
NC score	0.117026 (rank : 330)	θ value	0.0330416 (rank : 181)
Query Neighborhood Hits	414	Target Neighborhood Hits	56	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y4P8, Q5MNZ8, Q6FI96, Q75L50, Q96IE4, Q9Y364	Gene names	WIPI2
Domain Architecture	No domain graphic available
Description	WD repeat domain phosphoinositide-interacting protein 2 (WIPI-2) (WIPI49-like protein 2).

WIPI2_MOUSE
NC score	0.108500 (rank : 331)	θ value	0.125558 (rank : 218)
Query Neighborhood Hits	414	Target Neighborhood Hits	55	Shared Neighborhood Hits	38
SwissProt Accessions	Q80W47	Gene names	Wipi2
Domain Architecture	No domain graphic available
Description	WD repeat domain phosphoinositide-interacting protein 2 (WIPI-2).

WIPI1_MOUSE
NC score	0.106688 (rank : 332)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	414	Target Neighborhood Hits	67	Shared Neighborhood Hits	49
SwissProt Accessions	Q8R3E3, Q8BGE1, Q8R1A9, Q8R1C7	Gene names	Wipi1, D11Ertd498e
Domain Architecture	No domain graphic available
Description	WD repeat domain phosphoinositide-interacting protein 1 (WIPI-1) (WD40 repeat protein interacting with phosphoinositides of 49 kDa) (WIPI 49 kDa).

TULP4_MOUSE
NC score	0.104598 (rank : 333)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	414	Target Neighborhood Hits	247	Shared Neighborhood Hits	86
SwissProt Accessions	Q9JIL5, Q8CA75, Q922C2	Gene names	Tulp4, Tusp
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

SSRP1_MOUSE
NC score	0.104446 (rank : 334)	θ value	0.00175202 (rank : 118)
Query Neighborhood Hits	414	Target Neighborhood Hits	193	Shared Neighborhood Hits	32
SwissProt Accessions	Q08943, Q3U9Z2, Q3UJ75, Q4V9U4, Q8CGA6	Gene names	Ssrp1
Domain Architecture
Description	FACT complex subunit SSRP1 (Facilitates chromatin transcription complex subunit SSRP1) (Structure-specific recognition protein 1) (Recombination signal sequence recognition protein 1) (T160).

TR95_HUMAN
NC score	0.103782 (rank : 335)	θ value	0.365318 (rank : 246)
Query Neighborhood Hits	414	Target Neighborhood Hits	50	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y2X0, Q6PJT2, Q96AD4, Q96I35, Q9Y652	Gene names	THRAP5, DRIP92
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein complex 95 kDa component (Trap95) (Thyroid hormone receptor-associated protein 5) (Vitamin D3 receptor-interacting protein complex component DRIP92).

SSRP1_HUMAN
NC score	0.103505 (rank : 336)	θ value	0.00298849 (rank : 131)
Query Neighborhood Hits	414	Target Neighborhood Hits	187	Shared Neighborhood Hits	30
SwissProt Accessions	Q08945, Q5BJG8	Gene names	SSRP1, FACT80
Domain Architecture
Description	FACT complex subunit SSRP1 (Facilitates chromatin transcription complex subunit SSRP1) (FACT 80 kDa subunit) (FACTp80) (Chromatin- specific transcription elongation factor 80 kDa subunit) (Structure- specific recognition protein 1) (hSSRP1) (Recombination signal sequence recognition protein 1) (T160).

IF39_MOUSE
NC score	0.098873 (rank : 337)	θ value	0.0330416 (rank : 173)
Query Neighborhood Hits	414	Target Neighborhood Hits	206	Shared Neighborhood Hits	23
SwissProt Accessions	Q8JZQ9, Q922K2	Gene names	Eif3s9
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116).

MATR3_HUMAN
NC score	0.096487 (rank : 338)	θ value	0.00509761 (rank : 138)
Query Neighborhood Hits	414	Target Neighborhood Hits	325	Shared Neighborhood Hits	41
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

IF39_HUMAN
NC score	0.096248 (rank : 339)	θ value	0.0431538 (rank : 183)
Query Neighborhood Hits	414	Target Neighborhood Hits	187	Shared Neighborhood Hits	23
SwissProt Accessions	P55884, Q9UMF9	Gene names	EIF3S9
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116) (eIF3 p110) (eIF3b) (Prt1 homolog) (hPrt1).

TULP4_HUMAN
NC score	0.095824 (rank : 340)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	414	Target Neighborhood Hits	426	Shared Neighborhood Hits	90
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

MATR3_MOUSE
NC score	0.093800 (rank : 341)	θ value	0.00509761 (rank : 139)
Query Neighborhood Hits	414	Target Neighborhood Hits	321	Shared Neighborhood Hits	37
SwissProt Accessions	Q8K310	Gene names	Matr3
Domain Architecture	No domain graphic available
Description	Matrin-3.

WIPI1_HUMAN
NC score	0.092120 (rank : 342)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	414	Target Neighborhood Hits	60	Shared Neighborhood Hits	44
SwissProt Accessions	Q5MNZ9, Q8IXM5, Q9NWF8	Gene names	WIPI1, WIPI49
Domain Architecture	No domain graphic available
Description	WD repeat domain phosphoinositide-interacting protein 1 (WIPI-1) (WD40 repeat protein interacting with phosphoinositides of 49 kDa) (WIPI 49 kDa) (Atg18 protein homolog).

DSPP_HUMAN
NC score	0.088294 (rank : 343)	θ value	0.000602161 (rank : 103)
Query Neighborhood Hits	414	Target Neighborhood Hits	645	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

WDR54_HUMAN
NC score	0.081798 (rank : 344)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	414	Target Neighborhood Hits	70	Shared Neighborhood Hits	57
SwissProt Accessions	Q9H977, Q53H85, Q86V45	Gene names	WDR54
Domain Architecture	No domain graphic available
Description	WD repeat protein 54.

WDR76_HUMAN
NC score	0.079215 (rank : 345)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	414	Target Neighborhood Hits	73	Shared Neighborhood Hits	51
SwissProt Accessions	Q9H967	Gene names	WDR76
Domain Architecture	No domain graphic available
Description	WD repeat protein 76.

WIPI3_MOUSE
NC score	0.071578 (rank : 346)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	414	Target Neighborhood Hits	51	Shared Neighborhood Hits	39
SwissProt Accessions	Q9CR39, Q3U924	Gene names	Wdr45l, Wipi3
Domain Architecture	No domain graphic available
Description	WD repeat domain phosphoinositide-interacting protein 3 (WIPI-3) (WD repeat protein 45-like) (WDR45-like protein).

WIPI3_HUMAN
NC score	0.071162 (rank : 347)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	414	Target Neighborhood Hits	53	Shared Neighborhood Hits	38
SwissProt Accessions	Q5MNZ6, O95328, Q6IBN2	Gene names	WDR45L, WIPI3
Domain Architecture	No domain graphic available
Description	WD repeat domain phosphoinositide-interacting protein 3 (WIPI-3) (WD repeat protein 45-like) (WDR45-like protein) (WIPI49-like protein).

DSPP_MOUSE
NC score	0.070812 (rank : 348)	θ value	0.0736092 (rank : 194)
Query Neighborhood Hits	414	Target Neighborhood Hits	491	Shared Neighborhood Hits	44
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

AF9_HUMAN
NC score	0.070495 (rank : 349)	θ value	0.000602161 (rank : 102)
Query Neighborhood Hits	414	Target Neighborhood Hits	202	Shared Neighborhood Hits	18
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

DMP1_HUMAN
NC score	0.064190 (rank : 350)	θ value	0.365318 (rank : 238)
Query Neighborhood Hits	414	Target Neighborhood Hits	491	Shared Neighborhood Hits	49
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

LEO1_MOUSE
NC score	0.063701 (rank : 351)	θ value	0.0736092 (rank : 195)
Query Neighborhood Hits	414	Target Neighborhood Hits	946	Shared Neighborhood Hits	73
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

DMP1_MOUSE
NC score	0.063038 (rank : 352)	θ value	0.279714 (rank : 231)
Query Neighborhood Hits	414	Target Neighborhood Hits	498	Shared Neighborhood Hits	51
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

LEO1_HUMAN
NC score	0.061448 (rank : 353)	θ value	0.47712 (rank : 251)
Query Neighborhood Hits	414	Target Neighborhood Hits	958	Shared Neighborhood Hits	72
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

NOLC1_HUMAN
NC score	0.061431 (rank : 354)	θ value	0.00509761 (rank : 141)
Query Neighborhood Hits	414	Target Neighborhood Hits	452	Shared Neighborhood Hits	35
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

NIPBL_HUMAN
NC score	0.060086 (rank : 355)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	414	Target Neighborhood Hits	1311	Shared Neighborhood Hits	99
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

HMGB3_MOUSE
NC score	0.059807 (rank : 356)	θ value	0.163984 (rank : 221)
Query Neighborhood Hits	414	Target Neighborhood Hits	88	Shared Neighborhood Hits	22
SwissProt Accessions	O54879	Gene names	Hmgb3, Hmg2a, Hmg4
Domain Architecture
Description	High mobility group protein B3 (High mobility group protein 4) (HMG-4) (High mobility group protein 2a) (HMG-2a).

HMGB3_HUMAN
NC score	0.056272 (rank : 357)	θ value	0.47712 (rank : 250)
Query Neighborhood Hits	414	Target Neighborhood Hits	86	Shared Neighborhood Hits	21
SwissProt Accessions	O15347, O95556, Q6NS40	Gene names	HMGB3, HMG2A, HMG4
Domain Architecture
Description	High mobility group protein B3 (High mobility group protein 4) (HMG-4) (High mobility group protein 2a) (HMG-2a).

HPS5_MOUSE
NC score	0.051708 (rank : 358)	θ value	0.62314 (rank : 261)
Query Neighborhood Hits	414	Target Neighborhood Hits	69	Shared Neighborhood Hits	18
SwissProt Accessions	P59438	Gene names	Hps5, Ru2
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 5 protein homolog (Ruby-eye protein 2) (Ru2).

HPS5_HUMAN
NC score	0.050679 (rank : 359)	θ value	2.36792 (rank : 314)
Query Neighborhood Hits	414	Target Neighborhood Hits	51	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UPZ3, O95942, Q8N4U0	Gene names	HPS5, AIBP63, KIAA1017
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 5 protein (Alpha-integrin-binding protein 63) (Ruby-eye protein 2 homolog) (Ru2).

NPBL_MOUSE
NC score	0.050529 (rank : 360)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	414	Target Neighborhood Hits	1041	Shared Neighborhood Hits	85
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

WIPI4_MOUSE
NC score	0.050169 (rank : 361)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	414	Target Neighborhood Hits	47	Shared Neighborhood Hits	33
SwissProt Accessions	Q91VM3, Q9CVF7, Q9JIG9	Gene names	Wdr45, DXImx38e, Wdrx1, Wipi4
Domain Architecture	No domain graphic available
Description	WD repeat domain phosphoinositide-interacting protein 4 (WIPI-4) (WD repeat protein 45) (WD repeat domain X-linked 1).

PSIP1_HUMAN
NC score	0.049423 (rank : 362)	θ value	0.125558 (rank : 213)
Query Neighborhood Hits	414	Target Neighborhood Hits	341	Shared Neighborhood Hits	32
SwissProt Accessions	O75475, O00256, O95368, Q6P391, Q86YB9, Q9NZI3, Q9UER6	Gene names	PSIP1, DFS70, LEDGF, PSIP2
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (Transcriptional coactivator p75/p52) (Dense fine speckles 70 kDa protein) (DFS 70) (CLL-associated antigen KW-7).

LYRIC_HUMAN
NC score	0.046864 (rank : 363)	θ value	0.62314 (rank : 263)
Query Neighborhood Hits	414	Target Neighborhood Hits	99	Shared Neighborhood Hits	20
SwissProt Accessions	Q86UE4, Q6PK07, Q8TCX3	Gene names	MTDH, AEG1, LYRIC
Domain Architecture	No domain graphic available
Description	Protein LYRIC (Lysine-rich CEACAM1 co-isolated protein) (3D3/lyric) (Metastasis adhesion protein) (Metadherin) (Astrocyte elevated gene-1 protein) (AEG-1).

SFRIP_HUMAN
NC score	0.045541 (rank : 364)	θ value	1.81305 (rank : 308)
Query Neighborhood Hits	414	Target Neighborhood Hits	530	Shared Neighborhood Hits	50
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

NOL8_HUMAN
NC score	0.044591 (rank : 365)	θ value	0.365318 (rank : 242)
Query Neighborhood Hits	414	Target Neighborhood Hits	297	Shared Neighborhood Hits	34
SwissProt Accessions	Q76FK4, Q5TCC7, Q5TCC8, Q5TCD3, Q5TCD5, Q5TCD6, Q5TCD7, Q76D35, Q7L3E2, Q9H586, Q9H795, Q9H7W7, Q9H9J6, Q9NWA4, Q9NWM4	Gene names	NOL8, NOP132
Domain Architecture	No domain graphic available
Description	Nucleolar protein 8 (Nucleolar protein Nop132).

BBX_MOUSE
NC score	0.043845 (rank : 366)	θ value	0.0736092 (rank : 192)
Query Neighborhood Hits	414	Target Neighborhood Hits	152	Shared Neighborhood Hits	26
SwissProt Accessions	Q8VBW5, Q3TZK1, Q6NXY8, Q6PEU3, Q8BQJ7, Q8C7E0, Q8CDQ0, Q8CDV1, Q8VI48, Q8VI49, Q8VI50, Q9CS94	Gene names	Bbx, Hbp2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

LYRIC_MOUSE
NC score	0.042374 (rank : 367)	θ value	3.0926 (rank : 328)
Query Neighborhood Hits	414	Target Neighborhood Hits	126	Shared Neighborhood Hits	20
SwissProt Accessions	Q80WJ7, Q3U9F8, Q3UAQ8, Q8BN67, Q8CBT9, Q8CDL0, Q8CGI7, Q9D052	Gene names	Mtdh, Lyric
Domain Architecture	No domain graphic available
Description	Protein LYRIC (Lysine-rich CEACAM1 co-isolated protein) (3D3/LYRIC) (Metastasis adhesion protein) (Metadherin).

UBF1_HUMAN
NC score	0.039609 (rank : 368)	θ value	5.27518 (rank : 361)
Query Neighborhood Hits	414	Target Neighborhood Hits	415	Shared Neighborhood Hits	51
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

MAP1B_MOUSE
NC score	0.037884 (rank : 369)	θ value	0.279714 (rank : 234)
Query Neighborhood Hits	414	Target Neighborhood Hits	977	Shared Neighborhood Hits	67
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

FANCM_HUMAN
NC score	0.036317 (rank : 370)	θ value	0.0563607 (rank : 187)
Query Neighborhood Hits	414	Target Neighborhood Hits	210	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

BAZ2B_HUMAN
NC score	0.036280 (rank : 371)	θ value	0.163984 (rank : 220)
Query Neighborhood Hits	414	Target Neighborhood Hits	803	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

MS3L1_MOUSE
NC score	0.035173 (rank : 372)	θ value	0.163984 (rank : 222)
Query Neighborhood Hits	414	Target Neighborhood Hits	67	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WVG9	Gene names	Msl3l1, Msl31
Domain Architecture
Description	Male-specific lethal 3-like 1 (MSL3-like 1) (Male-specific lethal-3 homolog 1).

SOX15_HUMAN
NC score	0.034659 (rank : 373)	θ value	0.47712 (rank : 255)
Query Neighborhood Hits	414	Target Neighborhood Hits	134	Shared Neighborhood Hits	20
SwissProt Accessions	O60248, P35717, Q9Y6W7	Gene names	SOX15, SOX12, SOX20, SOX26, SOX27
Domain Architecture
Description	SOX-15 protein (SOX-20 protein) (SOX-12 protein).

AFF4_HUMAN
NC score	0.032425 (rank : 374)	θ value	1.38821 (rank : 294)
Query Neighborhood Hits	414	Target Neighborhood Hits	611	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

THOC2_HUMAN
NC score	0.032352 (rank : 375)	θ value	1.81305 (rank : 309)
Query Neighborhood Hits	414	Target Neighborhood Hits	337	Shared Neighborhood Hits	36
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

TCF20_MOUSE
NC score	0.031958 (rank : 376)	θ value	0.365318 (rank : 245)
Query Neighborhood Hits	414	Target Neighborhood Hits	396	Shared Neighborhood Hits	31
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

SOX30_HUMAN
NC score	0.031334 (rank : 377)	θ value	2.36792 (rank : 323)
Query Neighborhood Hits	414	Target Neighborhood Hits	305	Shared Neighborhood Hits	32
SwissProt Accessions	O94993, O94995, Q8IYX6	Gene names	SOX30
Domain Architecture
Description	Transcription factor SOX-30.

SOX15_MOUSE
NC score	0.030556 (rank : 378)	θ value	3.0926 (rank : 329)
Query Neighborhood Hits	414	Target Neighborhood Hits	100	Shared Neighborhood Hits	20
SwissProt Accessions	P43267, O70204, P70418, Q62246, Q91V00, Q91V43, Q920T1, Q9JLG2	Gene names	Sox15, Sox-15
Domain Architecture
Description	SOX-15 protein.

ANLN_HUMAN
NC score	0.030184 (rank : 379)	θ value	1.81305 (rank : 301)
Query Neighborhood Hits	414	Target Neighborhood Hits	222	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NQW6, Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0	Gene names	ANLN
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

SRRM2_MOUSE
NC score	0.029550 (rank : 380)	θ value	0.813845 (rank : 273)
Query Neighborhood Hits	414	Target Neighborhood Hits	1470	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

ACD_MOUSE
NC score	0.029224 (rank : 381)	θ value	0.813845 (rank : 267)
Query Neighborhood Hits	414	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q5EE38, Q3TBB1, Q3TUR7, Q3UKL6, Q3V3Y1, Q99KF8	Gene names	Acd
Domain Architecture	No domain graphic available
Description	Adrenocortical dysplasia protein.

AKAP2_MOUSE
NC score	0.028892 (rank : 382)	θ value	1.06291 (rank : 278)
Query Neighborhood Hits	414	Target Neighborhood Hits	385	Shared Neighborhood Hits	29
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

LIMA1_HUMAN
NC score	0.028786 (rank : 383)	θ value	0.279714 (rank : 233)
Query Neighborhood Hits	414	Target Neighborhood Hits	309	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UHB6, Q2TAN7, Q9BVF2, Q9H8J1, Q9HBN5, Q9NX96, Q9NXC3, Q9NXU6, Q9P0H8, Q9UHB5	Gene names	LIMA1, EPLIN, SREBP3
Domain Architecture
Description	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm).

SRRM2_HUMAN
NC score	0.028676 (rank : 384)	θ value	0.47712 (rank : 256)
Query Neighborhood Hits	414	Target Neighborhood Hits	1296	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SAFB2_MOUSE
NC score	0.027955 (rank : 385)	θ value	0.0563607 (rank : 189)
Query Neighborhood Hits	414	Target Neighborhood Hits	581	Shared Neighborhood Hits	27
SwissProt Accessions	Q80YR5, Q8K153	Gene names	Safb2
Domain Architecture
Description	Scaffold attachment factor B2.

CALD1_HUMAN
NC score	0.027770 (rank : 386)	θ value	0.0193708 (rank : 160)
Query Neighborhood Hits	414	Target Neighborhood Hits	959	Shared Neighborhood Hits	50
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

SOX17_HUMAN
NC score	0.027720 (rank : 387)	θ value	2.36792 (rank : 322)
Query Neighborhood Hits	414	Target Neighborhood Hits	108	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H6I2	Gene names	SOX17
Domain Architecture
Description	Transcription factor SOX-17.

SOX30_MOUSE
NC score	0.027486 (rank : 388)	θ value	4.03905 (rank : 344)
Query Neighborhood Hits	414	Target Neighborhood Hits	374	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

CENPC_MOUSE
NC score	0.027064 (rank : 389)	θ value	1.06291 (rank : 280)
Query Neighborhood Hits	414	Target Neighborhood Hits	154	Shared Neighborhood Hits	18
SwissProt Accessions	P49452	Gene names	Cenpc1, Cenpc
Domain Architecture	No domain graphic available
Description	Centromere protein C 1 (CENP-C) (Centromere autoantigen C).

SOX14_HUMAN
NC score	0.026710 (rank : 390)	θ value	6.88961 (rank : 381)
Query Neighborhood Hits	414	Target Neighborhood Hits	102	Shared Neighborhood Hits	21
SwissProt Accessions	O95416, Q3KPH7	Gene names	SOX14, SOX28
Domain Architecture
Description	Transcription factor SOX-14.

SOX14_MOUSE
NC score	0.026556 (rank : 391)	θ value	6.88961 (rank : 382)
Query Neighborhood Hits	414	Target Neighborhood Hits	100	Shared Neighborhood Hits	21
SwissProt Accessions	Q04892, Q9JLC9, Q9JLD0, Q9QXU4	Gene names	Sox14, Sox-14
Domain Architecture
Description	Transcription factor SOX-14.

SOX1_HUMAN
NC score	0.026475 (rank : 392)	θ value	6.88961 (rank : 384)
Query Neighborhood Hits	414	Target Neighborhood Hits	90	Shared Neighborhood Hits	20
SwissProt Accessions	O00570	Gene names	SOX1
Domain Architecture
Description	SOX-1 protein.

SOX1_MOUSE
NC score	0.026410 (rank : 393)	θ value	6.88961 (rank : 385)
Query Neighborhood Hits	414	Target Neighborhood Hits	90	Shared Neighborhood Hits	20
SwissProt Accessions	P53783	Gene names	Sox1, Sox-1
Domain Architecture
Description	SOX-1 protein.

EDD1_MOUSE
NC score	0.026394 (rank : 394)	θ value	0.47712 (rank : 249)
Query Neighborhood Hits	414	Target Neighborhood Hits	167	Shared Neighborhood Hits	11
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

SOX2_MOUSE
NC score	0.026165 (rank : 395)	θ value	8.99809 (rank : 409)
Query Neighborhood Hits	414	Target Neighborhood Hits	90	Shared Neighborhood Hits	22
SwissProt Accessions	P48432	Gene names	Sox2, Sox-2
Domain Architecture
Description	Transcription factor SOX-2.

SOX2_HUMAN
NC score	0.026087 (rank : 396)	θ value	8.99809 (rank : 408)
Query Neighborhood Hits	414	Target Neighborhood Hits	89	Shared Neighborhood Hits	22
SwissProt Accessions	P48431, Q14537	Gene names	SOX2
Domain Architecture
Description	Transcription factor SOX-2.

SRY_MOUSE
NC score	0.025979 (rank : 397)	θ value	8.99809 (rank : 410)
Query Neighborhood Hits	414	Target Neighborhood Hits	139	Shared Neighborhood Hits	25
SwissProt Accessions	Q05738	Gene names	Sry, Tdf, Tdy
Domain Architecture
Description	Sex-determining region Y protein (Testis-determining factor).

LBXCO_MOUSE
NC score	0.025865 (rank : 398)	θ value	2.36792 (rank : 316)
Query Neighborhood Hits	414	Target Neighborhood Hits	140	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BX46, Q3UYA4, Q5W8I2, Q8C0T2	Gene names	Lbxcor1, Corl1
Domain Architecture	No domain graphic available
Description	Ladybird homeobox corepressor 1 (Transcriptional corepressor Corl1).

SFR11_HUMAN
NC score	0.025739 (rank : 399)	θ value	6.88961 (rank : 380)
Query Neighborhood Hits	414	Target Neighborhood Hits	246	Shared Neighborhood Hits	23
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

CTR9_MOUSE
NC score	0.025570 (rank : 400)	θ value	1.06291 (rank : 281)
Query Neighborhood Hits	414	Target Neighborhood Hits	427	Shared Neighborhood Hits	24
SwissProt Accessions	Q62018, Q3UFF5, Q3UY40, Q66JX4, Q7TPS6, Q8BND9, Q8BRD1, Q8C9W7, Q8C9Y3, Q8CHI1	Gene names	Ctr9, Kiaa0155, Sh2bp1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) (Tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa) (TPR-containing, SH2-binding phosphoprotein of 150 kDa) (p150TSP).

LBXCO_HUMAN
NC score	0.025547 (rank : 401)	θ value	2.36792 (rank : 315)
Query Neighborhood Hits	414	Target Neighborhood Hits	167	Shared Neighborhood Hits	8
SwissProt Accessions	P84550	Gene names	LBXCOR1
Domain Architecture	No domain graphic available
Description	Ladybird homeobox corepressor 1.

E41L3_MOUSE
NC score	0.025440 (rank : 402)	θ value	0.00298849 (rank : 128)
Query Neighborhood Hits	414	Target Neighborhood Hits	250	Shared Neighborhood Hits	23
SwissProt Accessions	Q9WV92, Q9R102	Gene names	Epb41l3, Dal1, Epb4.1l3
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1).

BRD4_MOUSE
NC score	0.025355 (rank : 403)	θ value	0.813845 (rank : 269)
Query Neighborhood Hits	414	Target Neighborhood Hits	845	Shared Neighborhood Hits	40
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

ARI1A_HUMAN
NC score	0.025138 (rank : 404)	θ value	0.163984 (rank : 219)
Query Neighborhood Hits	414	Target Neighborhood Hits	787	Shared Neighborhood Hits	24
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

SFRS4_HUMAN
NC score	0.024777 (rank : 405)	θ value	1.06291 (rank : 290)
Query Neighborhood Hits	414	Target Neighborhood Hits	384	Shared Neighborhood Hits	26
SwissProt Accessions	Q08170, Q5VXP1, Q9BUA4, Q9UEB5	Gene names	SFRS4, SRP75
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB).

SOX17_MOUSE
NC score	0.024758 (rank : 406)	θ value	6.88961 (rank : 383)
Query Neighborhood Hits	414	Target Neighborhood Hits	223	Shared Neighborhood Hits	20
SwissProt Accessions	Q61473, Q61472, Q62248	Gene names	Sox17, Sox-17
Domain Architecture
Description	Transcription factor SOX-17.

EDD1_HUMAN
NC score	0.024613 (rank : 407)	θ value	1.06291 (rank : 284)
Query Neighborhood Hits	414	Target Neighborhood Hits	170	Shared Neighborhood Hits	10
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

MINT_HUMAN
NC score	0.024409 (rank : 408)	θ value	1.81305 (rank : 305)
Query Neighborhood Hits	414	Target Neighborhood Hits	1291	Shared Neighborhood Hits	73
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NFM_MOUSE
NC score	0.023612 (rank : 409)	θ value	0.00102713 (rank : 110)
Query Neighborhood Hits	414	Target Neighborhood Hits	1159	Shared Neighborhood Hits	68
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

BRD4_HUMAN
NC score	0.023404 (rank : 410)	θ value	2.36792 (rank : 312)
Query Neighborhood Hits	414	Target Neighborhood Hits	851	Shared Neighborhood Hits	41
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

TCOF_MOUSE
NC score	0.023295 (rank : 411)	θ value	0.813845 (rank : 274)
Query Neighborhood Hits	414	Target Neighborhood Hits	471	Shared Neighborhood Hits	24
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

LZTS1_MOUSE
NC score	0.023098 (rank : 412)	θ value	0.21417 (rank : 229)
Query Neighborhood Hits	414	Target Neighborhood Hits	540	Shared Neighborhood Hits	29
SwissProt Accessions	P60853	Gene names	Lzts1, Fez1
Domain Architecture	No domain graphic available
Description	Leucine zipper putative tumor suppressor 1 (F37/Esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

RPGR_HUMAN
NC score	0.022885 (rank : 413)	θ value	2.36792 (rank : 320)
Query Neighborhood Hits	414	Target Neighborhood Hits	279	Shared Neighborhood Hits	29
SwissProt Accessions	Q92834, O00702, O00737, Q8N5T6, Q93039, Q9HD29, Q9UMR1	Gene names	RPGR, RP3, XLRP3
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator.

BAZ1A_HUMAN
NC score	0.022837 (rank : 414)	θ value	8.99809 (rank : 393)
Query Neighborhood Hits	414	Target Neighborhood Hits	693	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

AP3B1_MOUSE
NC score	0.022295 (rank : 415)	θ value	0.62314 (rank : 258)
Query Neighborhood Hits	414	Target Neighborhood Hits	302	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z1T1, Q91YR4	Gene names	Ap3b1
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

RRMJ3_MOUSE
NC score	0.022014 (rank : 416)	θ value	2.36792 (rank : 321)
Query Neighborhood Hits	414	Target Neighborhood Hits	163	Shared Neighborhood Hits	11
SwissProt Accessions	Q9DBE9, Q3ULI1, Q921I7	Gene names	Ftsj3
Domain Architecture	No domain graphic available
Description	Putative rRNA methyltransferase 3 (EC 2.1.1.-) (rRNA (uridine-2'-O-)- methyltransferase 3).

CBP_HUMAN
NC score	0.022007 (rank : 417)	θ value	6.88961 (rank : 365)
Query Neighborhood Hits	414	Target Neighborhood Hits	941	Shared Neighborhood Hits	36
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

ZN318_HUMAN
NC score	0.021837 (rank : 418)	θ value	3.0926 (rank : 332)
Query Neighborhood Hits	414	Target Neighborhood Hits	497	Shared Neighborhood Hits	30
SwissProt Accessions	Q5VUA4, O94796, Q4G0E4, Q8NEM6, Q9UNU8, Q9Y2W9	Gene names	ZNF318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Endocrine regulatory protein).

NFM_HUMAN
NC score	0.020742 (rank : 419)	θ value	0.813845 (rank : 272)
Query Neighborhood Hits	414	Target Neighborhood Hits	1328	Shared Neighborhood Hits	76
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

DEK_MOUSE
NC score	0.020684 (rank : 420)	θ value	4.03905 (rank : 335)
Query Neighborhood Hits	414	Target Neighborhood Hits	280	Shared Neighborhood Hits	17
SwissProt Accessions	Q7TNV0, Q80VC5, Q8BZV6	Gene names	Dek
Domain Architecture	No domain graphic available
Description	Protein DEK.

MORC2_HUMAN
NC score	0.020552 (rank : 421)	θ value	0.365318 (rank : 241)
Query Neighborhood Hits	414	Target Neighborhood Hits	207	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y6X9, Q9UF28, Q9Y6V2	Gene names	MORC2, KIAA0852, ZCWCC1
Domain Architecture
Description	MORC family CW-type zinc finger protein 2 (Zinc finger CW-type coiled- coil domain protein 1).

ZCHC7_HUMAN
NC score	0.020250 (rank : 422)	θ value	4.03905 (rank : 349)
Query Neighborhood Hits	414	Target Neighborhood Hits	73	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N3Z6, Q5T0Q8, Q5T0Q9, Q5T0R0, Q8N2M1, Q8N4J2, Q8TBK8, Q9H648, Q9P0F0	Gene names	ZCCHC7
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 7.

CAF1A_HUMAN
NC score	0.019341 (rank : 423)	θ value	1.38821 (rank : 295)
Query Neighborhood Hits	414	Target Neighborhood Hits	750	Shared Neighborhood Hits	36
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

AFF1_HUMAN
NC score	0.019239 (rank : 424)	θ value	5.27518 (rank : 352)
Query Neighborhood Hits	414	Target Neighborhood Hits	506	Shared Neighborhood Hits	37
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

LZTS1_HUMAN
NC score	0.018954 (rank : 425)	θ value	5.27518 (rank : 359)
Query Neighborhood Hits	414	Target Neighborhood Hits	532	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y250, Q9Y5V7, Q9Y5V8, Q9Y5V9, Q9Y5W0, Q9Y5W1, Q9Y5W2	Gene names	LZTS1, FEZ1
Domain Architecture
Description	Leucine zipper putative tumor suppressor 1 (F37/esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

ZRF1_HUMAN
NC score	0.018746 (rank : 426)	θ value	3.0926 (rank : 333)
Query Neighborhood Hits	414	Target Neighborhood Hits	457	Shared Neighborhood Hits	21
SwissProt Accessions	Q99543	Gene names	ZRF1, DNAJC2, MPHOSPH11, MPP11
Domain Architecture
Description	Zuotin-related factor 1 (M-phase phosphoprotein 11).

CING_HUMAN
NC score	0.018275 (rank : 427)	θ value	1.38821 (rank : 296)
Query Neighborhood Hits	414	Target Neighborhood Hits	1275	Shared Neighborhood Hits	67
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

DDX46_HUMAN
NC score	0.017803 (rank : 428)	θ value	0.125558 (rank : 208)
Query Neighborhood Hits	414	Target Neighborhood Hits	357	Shared Neighborhood Hits	22
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

ZRF1_MOUSE
NC score	0.017675 (rank : 429)	θ value	4.03905 (rank : 351)
Query Neighborhood Hits	414	Target Neighborhood Hits	414	Shared Neighborhood Hits	21
SwissProt Accessions	P54103	Gene names	Zrf1, Dnajc2
Domain Architecture
Description	Zuotin-related factor 1.

SMC3_MOUSE
NC score	0.017647 (rank : 430)	θ value	4.03905 (rank : 343)
Query Neighborhood Hits	414	Target Neighborhood Hits	1187	Shared Neighborhood Hits	64
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

SMC3_HUMAN
NC score	0.017600 (rank : 431)	θ value	4.03905 (rank : 342)
Query Neighborhood Hits	414	Target Neighborhood Hits	1186	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

DDX46_MOUSE
NC score	0.017201 (rank : 432)	θ value	0.21417 (rank : 228)
Query Neighborhood Hits	414	Target Neighborhood Hits	358	Shared Neighborhood Hits	23
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

DDX21_HUMAN
NC score	0.016942 (rank : 433)	θ value	0.365318 (rank : 237)
Query Neighborhood Hits	414	Target Neighborhood Hits	308	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

TFG_HUMAN
NC score	0.016668 (rank : 434)	θ value	6.88961 (rank : 388)
Query Neighborhood Hits	414	Target Neighborhood Hits	122	Shared Neighborhood Hits	7
SwissProt Accessions	Q92734, Q15656	Gene names	TFG
Domain Architecture
Description	Protein TFG (TRK-fused gene protein).

DPOLZ_HUMAN
NC score	0.016350 (rank : 435)	θ value	3.0926 (rank : 326)
Query Neighborhood Hits	414	Target Neighborhood Hits	200	Shared Neighborhood Hits	21
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

EST1A_MOUSE
NC score	0.016125 (rank : 436)	θ value	4.03905 (rank : 338)
Query Neighborhood Hits	414	Target Neighborhood Hits	138	Shared Neighborhood Hits	13
SwissProt Accessions	P61406, Q5NC64	Gene names	Est1a, Kiaa0732
Domain Architecture
Description	Telomerase-binding protein EST1A (Ever shorter telomeres 1A) (Telomerase subunit EST1A) (EST1-like protein A).

CEP35_HUMAN
NC score	0.016041 (rank : 437)	θ value	8.99809 (rank : 394)
Query Neighborhood Hits	414	Target Neighborhood Hits	811	Shared Neighborhood Hits	57
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

NFH_HUMAN
NC score	0.015797 (rank : 438)	θ value	2.36792 (rank : 317)
Query Neighborhood Hits	414	Target Neighborhood Hits	1242	Shared Neighborhood Hits	74
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

MUC15_HUMAN
NC score	0.015714 (rank : 439)	θ value	4.03905 (rank : 339)
Query Neighborhood Hits	414	Target Neighborhood Hits	61	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N387, Q6UWS3, Q8IXI8, Q8WW41	Gene names	MUC15
Domain Architecture	No domain graphic available
Description	Mucin-15 precursor.

RRMJ3_HUMAN
NC score	0.015454 (rank : 440)	θ value	8.99809 (rank : 407)
Query Neighborhood Hits	414	Target Neighborhood Hits	88	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IY81, Q8N3A3, Q8WXX1, Q9BWM4, Q9NXT6	Gene names	FTSJ3
Domain Architecture	No domain graphic available
Description	Putative rRNA methyltransferase 3 (EC 2.1.1.-) (rRNA (uridine-2'-O-)- methyltransferase 3).

TTF1_HUMAN
NC score	0.015391 (rank : 441)	θ value	4.03905 (rank : 347)
Query Neighborhood Hits	414	Target Neighborhood Hits	68	Shared Neighborhood Hits	7
SwissProt Accessions	Q15361, Q4VXF3, Q58EY2, Q6P5T5	Gene names	TTF1
Domain Architecture	No domain graphic available
Description	Transcription termination factor 1 (TTF-1) (TTF-I) (RNA polymerase I termination factor).

ABTAP_MOUSE
NC score	0.015192 (rank : 442)	θ value	8.99809 (rank : 390)
Query Neighborhood Hits	414	Target Neighborhood Hits	381	Shared Neighborhood Hits	32
SwissProt Accessions	Q3V1V3	Gene names	Abtap
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

CASP_MOUSE
NC score	0.014942 (rank : 443)	θ value	1.06291 (rank : 279)
Query Neighborhood Hits	414	Target Neighborhood Hits	1152	Shared Neighborhood Hits	52
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CLSPN_MOUSE
NC score	0.014700 (rank : 444)	θ value	8.99809 (rank : 395)
Query Neighborhood Hits	414	Target Neighborhood Hits	292	Shared Neighborhood Hits	26
SwissProt Accessions	Q80YR7, Q69GM2	Gene names	Clspn
Domain Architecture	No domain graphic available
Description	Claspin.

IF2P_HUMAN
NC score	0.014440 (rank : 445)	θ value	5.27518 (rank : 358)
Query Neighborhood Hits	414	Target Neighborhood Hits	889	Shared Neighborhood Hits	51
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

PCLO_MOUSE
NC score	0.014382 (rank : 446)	θ value	0.365318 (rank : 243)
Query Neighborhood Hits	414	Target Neighborhood Hits	2275	Shared Neighborhood Hits	88
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

E41LA_HUMAN
NC score	0.014055 (rank : 447)	θ value	1.81305 (rank : 304)
Query Neighborhood Hits	414	Target Neighborhood Hits	87	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HCS5	Gene names	EPB41L4A, EPB41L4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

CUTL1_MOUSE
NC score	0.013807 (rank : 448)	θ value	1.06291 (rank : 282)
Query Neighborhood Hits	414	Target Neighborhood Hits	1620	Shared Neighborhood Hits	66
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

ASXL1_HUMAN
NC score	0.013783 (rank : 449)	θ value	8.99809 (rank : 391)
Query Neighborhood Hits	414	Target Neighborhood Hits	260	Shared Neighborhood Hits	22
SwissProt Accessions	Q8IXJ9, Q5JWS9, Q8IYY7, Q9H466, Q9NQF8, Q9UFJ0, Q9UFP8, Q9Y2I4	Gene names	ASXL1, KIAA0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

HRX_HUMAN
NC score	0.013564 (rank : 450)	θ value	6.88961 (rank : 370)
Query Neighborhood Hits	414	Target Neighborhood Hits	825	Shared Neighborhood Hits	50
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

FYV1_HUMAN
NC score	0.012883 (rank : 451)	θ value	3.0926 (rank : 327)
Query Neighborhood Hits	414	Target Neighborhood Hits	217	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

K0586_HUMAN
NC score	0.012727 (rank : 452)	θ value	8.99809 (rank : 401)
Query Neighborhood Hits	414	Target Neighborhood Hits	311	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BVV6, O60328	Gene names	KIAA0586
Domain Architecture	No domain graphic available
Description	Protein KIAA0586.

TTF2_HUMAN
NC score	0.012439 (rank : 453)	θ value	0.813845 (rank : 276)
Query Neighborhood Hits	414	Target Neighborhood Hits	98	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UNY4, O75921, Q5T2K7, Q5VVU8, Q8N6I8	Gene names	TTF2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2) (Factor 2) (F2) (HuF2) (Lodestar homolog).

RB6I2_HUMAN
NC score	0.012030 (rank : 454)	θ value	6.88961 (rank : 377)
Query Neighborhood Hits	414	Target Neighborhood Hits	1584	Shared Neighborhood Hits	69
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

NELFA_MOUSE
NC score	0.011736 (rank : 455)	θ value	6.88961 (rank : 376)
Query Neighborhood Hits	414	Target Neighborhood Hits	195	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BG30, Q8BVE4, Q8VEI7, Q9CSJ9, Q9Z1V9	Gene names	Whsc2, Nelfa, Whsc2h
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 homolog) (mWHSC2).

PRG4_HUMAN
NC score	0.011483 (rank : 456)	θ value	2.36792 (rank : 318)
Query Neighborhood Hits	414	Target Neighborhood Hits	764	Shared Neighborhood Hits	40
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

GDE5_MOUSE
NC score	0.011393 (rank : 457)	θ value	5.27518 (rank : 356)
Query Neighborhood Hits	414	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C0L9, Q3TLV6, Q80TD5, Q8BKJ7, Q8BKW7, Q8CFW2, Q9D759	Gene names	Gde5, Kiaa1434, Prei4
Domain Architecture	No domain graphic available
Description	Putative glycerophosphodiester phosphodiesterase 5 (EC 3.1.-.-) (Preimplantation protein 4).

CHD1_HUMAN
NC score	0.011182 (rank : 458)	θ value	2.36792 (rank : 313)
Query Neighborhood Hits	414	Target Neighborhood Hits	337	Shared Neighborhood Hits	28
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

AN30A_HUMAN
NC score	0.011060 (rank : 459)	θ value	5.27518 (rank : 353)
Query Neighborhood Hits	414	Target Neighborhood Hits	1119	Shared Neighborhood Hits	68
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

MYST3_MOUSE
NC score	0.011057 (rank : 460)	θ value	6.88961 (rank : 375)
Query Neighborhood Hits	414	Target Neighborhood Hits	688	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

RB6I2_MOUSE
NC score	0.010758 (rank : 461)	θ value	8.99809 (rank : 406)
Query Neighborhood Hits	414	Target Neighborhood Hits	1433	Shared Neighborhood Hits	60
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

INCE_MOUSE
NC score	0.010725 (rank : 462)	θ value	6.88961 (rank : 372)
Query Neighborhood Hits	414	Target Neighborhood Hits	903	Shared Neighborhood Hits	40
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

MYH10_MOUSE
NC score	0.010514 (rank : 463)	θ value	1.06291 (rank : 286)
Query Neighborhood Hits	414	Target Neighborhood Hits	1612	Shared Neighborhood Hits	59
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

CDSN_MOUSE
NC score	0.010373 (rank : 464)	θ value	6.88961 (rank : 366)
Query Neighborhood Hits	414	Target Neighborhood Hits	131	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TPC1	Gene names	Cdsn
Domain Architecture	No domain graphic available
Description	Corneodesmosin precursor.

MYH10_HUMAN
NC score	0.010015 (rank : 465)	θ value	1.81305 (rank : 306)
Query Neighborhood Hits	414	Target Neighborhood Hits	1620	Shared Neighborhood Hits	62
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

TSH3_HUMAN
NC score	0.009523 (rank : 466)	θ value	1.81305 (rank : 310)
Query Neighborhood Hits	414	Target Neighborhood Hits	564	Shared Neighborhood Hits	8
SwissProt Accessions	Q63HK5, Q9H0G6, Q9P254	Gene names	TSHZ3, KIAA1474, TSH3, ZNF537
Domain Architecture	No domain graphic available
Description	Teashirt homolog 3 (Zinc finger protein 537).

MYH14_HUMAN
NC score	0.009467 (rank : 467)	θ value	1.06291 (rank : 287)
Query Neighborhood Hits	414	Target Neighborhood Hits	995	Shared Neighborhood Hits	35
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

ARMX5_HUMAN
NC score	0.009330 (rank : 468)	θ value	4.03905 (rank : 334)
Query Neighborhood Hits	414	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P1M9, Q68DB4, Q9BVZ3, Q9H969	Gene names	ARMCX5
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 5.

IFT81_MOUSE
NC score	0.009251 (rank : 469)	θ value	8.99809 (rank : 400)
Query Neighborhood Hits	414	Target Neighborhood Hits	959	Shared Neighborhood Hits	48
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

MLL3_HUMAN
NC score	0.009204 (rank : 470)	θ value	6.88961 (rank : 374)
Query Neighborhood Hits	414	Target Neighborhood Hits	1644	Shared Neighborhood Hits	57
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

TAXB1_HUMAN
NC score	0.009196 (rank : 471)	θ value	6.88961 (rank : 386)
Query Neighborhood Hits	414	Target Neighborhood Hits	829	Shared Neighborhood Hits	36
SwissProt Accessions	Q86VP1, O60398, O95770, Q13311, Q9BQG5, Q9UI88	Gene names	TAX1BP1, T6BP
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 (TRAF6-binding protein).

ESPL1_HUMAN
NC score	0.009164 (rank : 472)	θ value	6.88961 (rank : 368)
Query Neighborhood Hits	414	Target Neighborhood Hits	95	Shared Neighborhood Hits	5
SwissProt Accessions	Q14674	Gene names	ESPL1, ESP1, KIAA0165
Domain Architecture
Description	Separin (EC 3.4.22.49) (Separase) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein).

P52K_HUMAN
NC score	0.009093 (rank : 473)	θ value	8.99809 (rank : 403)
Query Neighborhood Hits	414	Target Neighborhood Hits	142	Shared Neighborhood Hits	10
SwissProt Accessions	O43422, Q8WTW1, Q9Y3Z4	Gene names	PRKRIR, DAP4, P52RIPK, THAP0
Domain Architecture
Description	52 kDa repressor of the inhibitor of the protein kinase (p58IPK- interacting protein) (58 kDa interferon-induced protein kinase- interacting protein) (P52rIPK) (Death-associated protein 4) (THAP domain-containing protein 0).

TEX9_HUMAN
NC score	0.008817 (rank : 474)	θ value	6.88961 (rank : 387)
Query Neighborhood Hits	414	Target Neighborhood Hits	541	Shared Neighborhood Hits	33
SwissProt Accessions	Q8N6V9	Gene names	TEX9
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 9 protein.

TSH3_MOUSE
NC score	0.008522 (rank : 475)	θ value	4.03905 (rank : 346)
Query Neighborhood Hits	414	Target Neighborhood Hits	590	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CGV9, Q5DTX4	Gene names	Tshz3, Kiaa1474, Tsh3, Zfp537, Znf537
Domain Architecture	No domain graphic available
Description	Teashirt homolog 3 (Zinc finger protein 537).

DDEF2_MOUSE
NC score	0.007940 (rank : 476)	θ value	1.06291 (rank : 283)
Query Neighborhood Hits	414	Target Neighborhood Hits	625	Shared Neighborhood Hits	11
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DNM3B_MOUSE
NC score	0.007831 (rank : 477)	θ value	5.27518 (rank : 355)
Query Neighborhood Hits	414	Target Neighborhood Hits	61	Shared Neighborhood Hits	7
SwissProt Accessions	O88509, O88510, O88511	Gene names	Dnmt3b
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3B (EC 2.1.1.37) (Dnmt3b) (DNA methyltransferase MmuIIIB) (DNA MTase MmuIIIB) (M.MmuIIIB).

ST5_HUMAN
NC score	0.006616 (rank : 478)	θ value	4.03905 (rank : 345)
Query Neighborhood Hits	414	Target Neighborhood Hits	151	Shared Neighborhood Hits	8
SwissProt Accessions	P78524, P78523, Q16492, Q7KYY2, Q7KZ12, Q8NE12, Q9BQQ6	Gene names	ST5, DENND2B, HTS1
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (HeLa tumor suppression 1) (DENN domain-containing protein 2B).

MYO9B_MOUSE
NC score	0.006120 (rank : 479)	θ value	4.03905 (rank : 340)
Query Neighborhood Hits	414	Target Neighborhood Hits	311	Shared Neighborhood Hits	16
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

G3BP_HUMAN
NC score	0.004938 (rank : 480)	θ value	6.88961 (rank : 369)
Query Neighborhood Hits	414	Target Neighborhood Hits	219	Shared Neighborhood Hits	6
SwissProt Accessions	Q13283	Gene names	G3BP, G3BP1
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 1 (EC 3.6.1.-) (ATP- dependent DNA helicase VIII) (GAP SH3-domain-binding protein 1) (G3BP- 1) (HDH-VIII).

SYTL5_MOUSE
NC score	0.004761 (rank : 481)	θ value	5.27518 (rank : 360)
Query Neighborhood Hits	414	Target Neighborhood Hits	154	Shared Neighborhood Hits	5
SwissProt Accessions	Q80T23, Q812E5	Gene names	Sytl5, Slp5
Domain Architecture
Description	Synaptotagmin-like protein 5.

ELK3_MOUSE
NC score	0.004178 (rank : 482)	θ value	4.03905 (rank : 336)
Query Neighborhood Hits	414	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	P41971, P97747, Q62346	Gene names	Elk3, Erp, Net
Domain Architecture
Description	ETS domain-containing protein Elk-3 (ETS-related protein NET) (ETS- related protein ERP).

PRP4B_MOUSE
NC score	0.002519 (rank : 483)	θ value	0.0961366 (rank : 203)
Query Neighborhood Hits	414	Target Neighborhood Hits	1040	Shared Neighborhood Hits	24
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

MAGD1_HUMAN
NC score	0.001248 (rank : 484)	θ value	8.99809 (rank : 402)
Query Neighborhood Hits	414	Target Neighborhood Hits	130	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y5V3, Q5VSH6, Q8IZ84, Q8WY92, Q9H352, Q9HBT4, Q9UF36	Gene names	MAGED1, NRAGE
Domain Architecture
Description	Melanoma-associated antigen D1 (MAGE-D1 antigen) (Neurotrophin receptor-interacting MAGE homolog) (MAGE tumor antigen CCF).

PRP4B_HUMAN
NC score	0.001200 (rank : 485)	θ value	1.06291 (rank : 288)
Query Neighborhood Hits	414	Target Neighborhood Hits	1030	Shared Neighborhood Hits	30
SwissProt Accessions	Q13523, Q8TDP2, Q96QT7, Q9UEE6	Gene names	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (PRP4 kinase).

MYPT2_HUMAN
NC score	0.000894 (rank : 486)	θ value	4.03905 (rank : 341)
Query Neighborhood Hits	414	Target Neighborhood Hits	707	Shared Neighborhood Hits	32
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

TLK1_MOUSE
NC score	0.000622 (rank : 487)	θ value	0.279714 (rank : 235)
Query Neighborhood Hits	414	Target Neighborhood Hits	947	Shared Neighborhood Hits	21
SwissProt Accessions	Q8C0V0	Gene names	Tlk1
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1) (Tousled- like kinase 1).

LAMA4_HUMAN
NC score	0.000077 (rank : 488)	θ value	6.88961 (rank : 373)
Query Neighborhood Hits	414	Target Neighborhood Hits	708	Shared Neighborhood Hits	21
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

RAI14_HUMAN
NC score	-0.000559 (rank : 489)	θ value	8.99809 (rank : 405)
Query Neighborhood Hits	414	Target Neighborhood Hits	1367	Shared Neighborhood Hits	45
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

PCDGC_HUMAN
NC score	-0.001906 (rank : 490)	θ value	1.81305 (rank : 307)
Query Neighborhood Hits	414	Target Neighborhood Hits	155	Shared Neighborhood Hits	2
SwissProt Accessions	O60330, O15100, Q6UW70, Q9Y5D7	Gene names	PCDHGA12, CDH21, FIB3, KIAA0588
Domain Architecture
Description	Protocadherin gamma A12 precursor (PCDH-gamma-A12) (Cadherin-21) (Fibroblast cadherin 3).

CD2L7_HUMAN
NC score	-0.003892 (rank : 491)	θ value	0.125558 (rank : 205)
Query Neighborhood Hits	414	Target Neighborhood Hits	1275	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

ATBF1_MOUSE
NC score	-0.005779 (rank : 492)	θ value	8.99809 (rank : 392)
Query Neighborhood Hits	414	Target Neighborhood Hits	1841	Shared Neighborhood Hits	56
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

GAK_MOUSE
NC score	-0.008148 (rank : 493)	θ value	8.99809 (rank : 398)
Query Neighborhood Hits	414	Target Neighborhood Hits	964	Shared Neighborhood Hits	16
SwissProt Accessions	Q99KY4, Q6P1I8, Q6P9S5, Q8BM74, Q8K0Q4	Gene names	Gak
Domain Architecture	No domain graphic available
Description	Cyclin G-associated kinase (EC 2.7.11.1).