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Network neighborhood for query Sequence : FANCM_HUMAN

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FANCM_HUMAN
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

FANCM_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	210	Target Neighborhood Hits	210	Shared Neighborhood Hits	210
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

FANCM_MOUSE
θ value	0 (rank : 2)	NC score	0.964189 (rank : 2)
Query Neighborhood Hits	210	Target Neighborhood Hits	177	Shared Neighborhood Hits	94
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

DDX58_HUMAN
θ value	1.02238e-19 (rank : 3)	NC score	0.539320 (rank : 7)
Query Neighborhood Hits	210	Target Neighborhood Hits	105	Shared Neighborhood Hits	60
SwissProt Accessions	O95786, Q5HYE1, Q5VYT1, Q9NT04	Gene names	DDX58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

DDX58_MOUSE
θ value	3.40345e-15 (rank : 4)	NC score	0.549683 (rank : 4)
Query Neighborhood Hits	210	Target Neighborhood Hits	99	Shared Neighborhood Hits	62
SwissProt Accessions	Q6Q899, Q8C320, Q8C5I3, Q8C7T2	Gene names	Ddx58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

IFIH1_MOUSE
θ value	2.43908e-13 (rank : 5)	NC score	0.546745 (rank : 5)
Query Neighborhood Hits	210	Target Neighborhood Hits	126	Shared Neighborhood Hits	79
SwissProt Accessions	Q8R5F7, Q3U6S2, Q68EM4, Q8BYC9, Q8BZ01, Q8K5C7, Q8R144, Q8VE79, Q99KS4, Q9D2Z5	Gene names	Ifih1
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5).

LGP2_HUMAN
θ value	4.16044e-13 (rank : 6)	NC score	0.549746 (rank : 3)
Query Neighborhood Hits	210	Target Neighborhood Hits	94	Shared Neighborhood Hits	71
SwissProt Accessions	Q96C10, Q9HAM6	Gene names	LGP2, D11LGP2E
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2 homolog).

IFIH1_HUMAN
θ value	4.59992e-12 (rank : 7)	NC score	0.538633 (rank : 8)
Query Neighborhood Hits	210	Target Neighborhood Hits	96	Shared Neighborhood Hits	74
SwissProt Accessions	Q9BYX4, Q6DC96, Q86X56, Q96MX8, Q9H3G6	Gene names	IFIH1, MDA5, RH116
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon-induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5) (RNA helicase-DEAD box protein 116) (Murabutide-down- regulated protein).

LGP2_MOUSE
θ value	1.74796e-11 (rank : 8)	NC score	0.544115 (rank : 6)
Query Neighborhood Hits	210	Target Neighborhood Hits	86	Shared Neighborhood Hits	68
SwissProt Accessions	Q99J87, Q9D1X4	Gene names	Lgp2, D11lgp2e
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2).

DICER_HUMAN
θ value	1.133e-10 (rank : 9)	NC score	0.496466 (rank : 9)
Query Neighborhood Hits	210	Target Neighborhood Hits	126	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UPY3, O95943, Q9UQ02	Gene names	DICER1, DICER, HERNA, KIAA0928
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Helicase with RNase motif) (Helicase-MOI).

DICER_MOUSE
θ value	1.9326e-10 (rank : 10)	NC score	0.494386 (rank : 10)
Query Neighborhood Hits	210	Target Neighborhood Hits	140	Shared Neighborhood Hits	81
SwissProt Accessions	Q8R418	Gene names	Dicer1, Dicer, Mdcr
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Double-strand-specific ribonuclease mDCR-1).

ERCC4_HUMAN
θ value	4.76016e-09 (rank : 11)	NC score	0.274711 (rank : 80)
Query Neighborhood Hits	210	Target Neighborhood Hits	32	Shared Neighborhood Hits	8
SwissProt Accessions	Q92889, O00140, Q8TD83	Gene names	ERCC4, ERCC11, XPF
Domain Architecture
Description	DNA repair endonuclease XPF (EC 3.1.-.-) (DNA excision repair protein ERCC-4) (DNA-repair protein complementing XP-F cells) (Xeroderma pigmentosum group F-complementing protein).

DDX27_HUMAN
θ value	3.41135e-07 (rank : 12)	NC score	0.458660 (rank : 14)
Query Neighborhood Hits	210	Target Neighborhood Hits	197	Shared Neighborhood Hits	87
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX21_HUMAN
θ value	5.81887e-07 (rank : 13)	NC score	0.462561 (rank : 11)
Query Neighborhood Hits	210	Target Neighborhood Hits	308	Shared Neighborhood Hits	95
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX27_MOUSE
θ value	5.81887e-07 (rank : 14)	NC score	0.457681 (rank : 15)
Query Neighborhood Hits	210	Target Neighborhood Hits	174	Shared Neighborhood Hits	86
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX21_MOUSE
θ value	1.69304e-06 (rank : 15)	NC score	0.456697 (rank : 16)
Query Neighborhood Hits	210	Target Neighborhood Hits	350	Shared Neighborhood Hits	92
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

ERCC4_MOUSE
θ value	1.69304e-06 (rank : 16)	NC score	0.235667 (rank : 82)
Query Neighborhood Hits	210	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QZD4, O54810, Q8R0I3	Gene names	Ercc4
Domain Architecture
Description	DNA repair endonuclease XPF (EC 3.1.-.-) (DNA excision repair protein ERCC-4).

DDX48_HUMAN
θ value	6.43352e-06 (rank : 17)	NC score	0.452942 (rank : 17)
Query Neighborhood Hits	210	Target Neighborhood Hits	102	Shared Neighborhood Hits	80
SwissProt Accessions	P38919, Q15033, Q96A18	Gene names	DDX48, EIF4A3, KIAA0111
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Nuclear matrix protein 265) (hNMP 265) (Eukaryotic translation initiation factor 4A isoform 3).

DDX48_MOUSE
θ value	6.43352e-06 (rank : 18)	NC score	0.452928 (rank : 18)
Query Neighborhood Hits	210	Target Neighborhood Hits	102	Shared Neighborhood Hits	80
SwissProt Accessions	Q91VC3	Gene names	Ddx48
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48).

DDX50_HUMAN
θ value	8.40245e-06 (rank : 19)	NC score	0.460298 (rank : 12)
Query Neighborhood Hits	210	Target Neighborhood Hits	132	Shared Neighborhood Hits	81
SwissProt Accessions	Q9BQ39, Q8WV76, Q9BWI8	Gene names	DDX50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX50_MOUSE
θ value	1.09739e-05 (rank : 20)	NC score	0.458929 (rank : 13)
Query Neighborhood Hits	210	Target Neighborhood Hits	137	Shared Neighborhood Hits	81
SwissProt Accessions	Q99MJ9	Gene names	Ddx50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX41_MOUSE
θ value	2.44474e-05 (rank : 21)	NC score	0.447928 (rank : 22)
Query Neighborhood Hits	210	Target Neighborhood Hits	115	Shared Neighborhood Hits	85
SwissProt Accessions	Q91VN6	Gene names	Ddx41
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41).

DDX18_HUMAN
θ value	3.19293e-05 (rank : 22)	NC score	0.436658 (rank : 39)
Query Neighborhood Hits	210	Target Neighborhood Hits	124	Shared Neighborhood Hits	76
SwissProt Accessions	Q9NVP1, Q6IAU4, Q92732, Q9BQB7	Gene names	DDX18
Domain Architecture
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb).

DDX3Y_MOUSE
θ value	4.1701e-05 (rank : 23)	NC score	0.447171 (rank : 26)
Query Neighborhood Hits	210	Target Neighborhood Hits	126	Shared Neighborhood Hits	84
SwissProt Accessions	Q62095, Q9QWS9	Gene names	Ddx3y, D1Pas1-rs1, Dead2
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal) (DEAD-box RNA helicase DEAD2) (mDEAD2) (D1Pas1-related sequence 1).

DDX41_HUMAN
θ value	5.44631e-05 (rank : 24)	NC score	0.447021 (rank : 27)
Query Neighborhood Hits	210	Target Neighborhood Hits	111	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UJV9, Q96BK6, Q96K05, Q9NT96, Q9NW04	Gene names	DDX41, ABS
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41) (DEAD box protein abstrakt homolog).

DDX49_MOUSE
θ value	5.44631e-05 (rank : 25)	NC score	0.441981 (rank : 36)
Query Neighborhood Hits	210	Target Neighborhood Hits	119	Shared Neighborhood Hits	84
SwissProt Accessions	Q4FZF3	Gene names	Ddx49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX18_MOUSE
θ value	7.1131e-05 (rank : 26)	NC score	0.439148 (rank : 38)
Query Neighborhood Hits	210	Target Neighborhood Hits	115	Shared Neighborhood Hits	75
SwissProt Accessions	Q8K363, Q3MIB0, Q8BVZ2, Q9D2E0	Gene names	Ddx18
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18).

DDX3X_HUMAN
θ value	9.29e-05 (rank : 27)	NC score	0.446066 (rank : 30)
Query Neighborhood Hits	210	Target Neighborhood Hits	122	Shared Neighborhood Hits	84
SwissProt Accessions	O00571, O15536	Gene names	DDX3X, DBX, DDX3
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (Helicase-like protein 2) (HLP2) (DEAD box, X isoform).

DDX3X_MOUSE
θ value	9.29e-05 (rank : 28)	NC score	0.446110 (rank : 29)
Query Neighborhood Hits	210	Target Neighborhood Hits	117	Shared Neighborhood Hits	84
SwissProt Accessions	Q62167, O09060, O09143	Gene names	Ddx3x, D1Pas1-rs2, Ddx3, Dead3, Erh
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (DEAD box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1Pas1-related sequence 2).

PL10_MOUSE
θ value	9.29e-05 (rank : 29)	NC score	0.444897 (rank : 34)
Query Neighborhood Hits	210	Target Neighborhood Hits	120	Shared Neighborhood Hits	84
SwissProt Accessions	P16381	Gene names	D1Pas1, Pl10
Domain Architecture
Description	Putative ATP-dependent RNA helicase Pl10 (EC 3.6.1.-).

DDX3Y_HUMAN
θ value	0.000121331 (rank : 30)	NC score	0.444863 (rank : 35)
Query Neighborhood Hits	210	Target Neighborhood Hits	121	Shared Neighborhood Hits	84
SwissProt Accessions	O15523, Q8IYV7	Gene names	DDX3Y, DBY
Domain Architecture
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal).

DDX51_HUMAN
θ value	0.000158464 (rank : 31)	NC score	0.449193 (rank : 20)
Query Neighborhood Hits	210	Target Neighborhood Hits	332	Shared Neighborhood Hits	88
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

HELC1_HUMAN
θ value	0.000158464 (rank : 32)	NC score	0.227583 (rank : 83)
Query Neighborhood Hits	210	Target Neighborhood Hits	71	Shared Neighborhood Hits	39
SwissProt Accessions	Q8N3C0, O43738, Q9H1I9, Q9NTR0	Gene names	ASCC3, HELIC1
Domain Architecture	No domain graphic available
Description	Activating signal cointegrator 1 complex subunit 3 (EC 3.6.1.-) (ASC-1 complex subunit p200) (Trip4 complex subunit p200) (Helicase, ATP binding 1).

DDX10_MOUSE
θ value	0.000270298 (rank : 33)	NC score	0.425148 (rank : 57)
Query Neighborhood Hits	210	Target Neighborhood Hits	233	Shared Neighborhood Hits	82
SwissProt Accessions	Q80Y44	Gene names	Ddx10
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX49_HUMAN
θ value	0.00035302 (rank : 34)	NC score	0.440888 (rank : 37)
Query Neighborhood Hits	210	Target Neighborhood Hits	223	Shared Neighborhood Hits	89
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX4_HUMAN
θ value	0.00035302 (rank : 35)	NC score	0.447395 (rank : 25)
Query Neighborhood Hits	210	Target Neighborhood Hits	123	Shared Neighborhood Hits	82
SwissProt Accessions	Q9NQI0, Q86VX0, Q9NT92, Q9NYB1	Gene names	DDX4, VASA
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog).

DDX4_MOUSE
θ value	0.00035302 (rank : 36)	NC score	0.448781 (rank : 21)
Query Neighborhood Hits	210	Target Neighborhood Hits	100	Shared Neighborhood Hits	82
SwissProt Accessions	Q61496, Q9D5X7	Gene names	Ddx4, Vasa
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog) (Mvh).

DDX52_MOUSE
θ value	0.000461057 (rank : 37)	NC score	0.446561 (rank : 28)
Query Neighborhood Hits	210	Target Neighborhood Hits	101	Shared Neighborhood Hits	81
SwissProt Accessions	Q8K301, Q8BV29	Gene names	Ddx52, Rok1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX51_MOUSE
θ value	0.000602161 (rank : 38)	NC score	0.451505 (rank : 19)
Query Neighborhood Hits	210	Target Neighborhood Hits	130	Shared Neighborhood Hits	80
SwissProt Accessions	Q6P9R1, Q3U7M2	Gene names	Ddx51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX31_HUMAN
θ value	0.000786445 (rank : 39)	NC score	0.431342 (rank : 45)
Query Neighborhood Hits	210	Target Neighborhood Hits	132	Shared Neighborhood Hits	83
SwissProt Accessions	Q9H8H2, Q5K6N2, Q5K6N3, Q5K6N4, Q5VZJ4, Q5VZJ9, Q96E91, Q96NY2, Q96SX5, Q9H5K6	Gene names	DDX31
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX31 (EC 3.6.1.-) (DEAD box protein 31) (Helicain).

DDX52_HUMAN
θ value	0.000786445 (rank : 40)	NC score	0.445780 (rank : 31)
Query Neighborhood Hits	210	Target Neighborhood Hits	107	Shared Neighborhood Hits	83
SwissProt Accessions	Q9Y2R4, Q86YG1, Q8N213, Q9NVE0, Q9Y482	Gene names	DDX52, ROK1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

IF4A1_HUMAN
θ value	0.000786445 (rank : 41)	NC score	0.447476 (rank : 23)
Query Neighborhood Hits	210	Target Neighborhood Hits	106	Shared Neighborhood Hits	78
SwissProt Accessions	P60842, P04765, Q5U018, Q61516	Gene names	EIF4A1, DDX2A, EIF4A
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A1_MOUSE
θ value	0.000786445 (rank : 42)	NC score	0.447476 (rank : 24)
Query Neighborhood Hits	210	Target Neighborhood Hits	106	Shared Neighborhood Hits	78
SwissProt Accessions	P60843, P04765, Q61516	Gene names	Eif4a1, Ddx2a, Eif4a
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A2_HUMAN
θ value	0.000786445 (rank : 43)	NC score	0.445740 (rank : 32)
Query Neighborhood Hits	210	Target Neighborhood Hits	102	Shared Neighborhood Hits	78
SwissProt Accessions	Q14240, Q96B90, Q96EA8	Gene names	EIF4A2, DDX2B
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A2_MOUSE
θ value	0.000786445 (rank : 44)	NC score	0.445740 (rank : 33)
Query Neighborhood Hits	210	Target Neighborhood Hits	102	Shared Neighborhood Hits	78
SwissProt Accessions	P10630, Q61513, Q61514	Gene names	Eif4a2, Ddx2b
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

DDX10_HUMAN
θ value	0.00102713 (rank : 45)	NC score	0.423928 (rank : 58)
Query Neighborhood Hits	210	Target Neighborhood Hits	210	Shared Neighborhood Hits	84
SwissProt Accessions	Q13206, Q5BJD8	Gene names	DDX10
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX39_MOUSE
θ value	0.00102713 (rank : 46)	NC score	0.427558 (rank : 52)
Query Neighborhood Hits	210	Target Neighborhood Hits	97	Shared Neighborhood Hits	77
SwissProt Accessions	Q8VDW0, Q3UJV4, Q8C2C2	Gene names	Ddx39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39).

DDX39_HUMAN
θ value	0.00134147 (rank : 47)	NC score	0.428185 (rank : 50)
Query Neighborhood Hits	210	Target Neighborhood Hits	94	Shared Neighborhood Hits	78
SwissProt Accessions	O00148, Q9BVP6, Q9H5W0	Gene names	DDX39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39) (Nuclear RNA helicase URH49).

DD19A_HUMAN
θ value	0.00298849 (rank : 48)	NC score	0.421541 (rank : 62)
Query Neighborhood Hits	210	Target Neighborhood Hits	107	Shared Neighborhood Hits	83
SwissProt Accessions	Q9NUU7, Q53FM0	Gene names	DDX19A, DDX19L
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DDX19-like protein).

DD19A_MOUSE
θ value	0.00298849 (rank : 49)	NC score	0.421860 (rank : 60)
Query Neighborhood Hits	210	Target Neighborhood Hits	105	Shared Neighborhood Hits	83
SwissProt Accessions	Q61655, Q921R0	Gene names	Ddx19a, Ddx19, Eif4a-rs1
Domain Architecture
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DEAD box RNA helicase DEAD5) (mDEAD5) (Eukaryotic translation initiation factor 4A-related sequence 1).

DD19B_HUMAN
θ value	0.00298849 (rank : 50)	NC score	0.421461 (rank : 63)
Query Neighborhood Hits	210	Target Neighborhood Hits	109	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UMR2, Q6FIB7, Q6IAE0	Gene names	DDX19B, DBP5, DDX19
Domain Architecture
Description	ATP-dependent RNA helicase DDX19B (EC 3.6.1.-) (DEAD box protein 19B) (DEAD box RNA helicase DEAD5).

DDX17_HUMAN
θ value	0.00298849 (rank : 51)	NC score	0.434223 (rank : 43)
Query Neighborhood Hits	210	Target Neighborhood Hits	104	Shared Neighborhood Hits	78
SwissProt Accessions	Q92841, Q69YT1, Q6ICD6	Gene names	DDX17
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17) (RNA-dependent helicase p72) (DEAD box protein p72).

DDX17_MOUSE
θ value	0.00298849 (rank : 52)	NC score	0.434293 (rank : 42)
Query Neighborhood Hits	210	Target Neighborhood Hits	105	Shared Neighborhood Hits	78
SwissProt Accessions	Q501J6, Q6P5G1, Q8BIN2	Gene names	Ddx17
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17).

DDX43_HUMAN
θ value	0.00298849 (rank : 53)	NC score	0.432082 (rank : 44)
Query Neighborhood Hits	210	Target Neighborhood Hits	120	Shared Neighborhood Hits	80
SwissProt Accessions	Q9NXZ2, Q6NXR1	Gene names	DDX43, HAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.1.-) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen).

DDX25_HUMAN
θ value	0.00390308 (rank : 54)	NC score	0.428805 (rank : 49)
Query Neighborhood Hits	210	Target Neighborhood Hits	93	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UHL0, Q86W81, Q8IYP1	Gene names	DDX25, GRTH
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX25_MOUSE
θ value	0.00390308 (rank : 55)	NC score	0.429950 (rank : 48)
Query Neighborhood Hits	210	Target Neighborhood Hits	98	Shared Neighborhood Hits	82
SwissProt Accessions	Q9QY15, Q8R1B6	Gene names	Ddx25, Grth
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

CCNB3_MOUSE
θ value	0.00509761 (rank : 56)	NC score	0.055271 (rank : 110)
Query Neighborhood Hits	210	Target Neighborhood Hits	211	Shared Neighborhood Hits	13
SwissProt Accessions	Q810T2, Q810T3, Q8VDC8	Gene names	Ccnb3, Cycb3
Domain Architecture
Description	G2/mitotic-specific cyclin-B3.

DDX23_HUMAN
θ value	0.00509761 (rank : 57)	NC score	0.423660 (rank : 59)
Query Neighborhood Hits	210	Target Neighborhood Hits	486	Shared Neighborhood Hits	101
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

UAP56_HUMAN
θ value	0.00509761 (rank : 58)	NC score	0.421333 (rank : 64)
Query Neighborhood Hits	210	Target Neighborhood Hits	96	Shared Neighborhood Hits	76
SwissProt Accessions	Q13838, O43496, Q5RJ64, Q5RJ66, Q5ST94, Q5STB4, Q5STB5, Q5STB7, Q5STU4, Q5STU5, Q5STU6, Q5STU8, Q71V76	Gene names	BAT1, UAP56
Domain Architecture
Description	Spliceosome RNA helicase BAT1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (HLA-B-associated transcript-1).

UAP56_MOUSE
θ value	0.00509761 (rank : 59)	NC score	0.421296 (rank : 65)
Query Neighborhood Hits	210	Target Neighborhood Hits	96	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Z1N5, Q8HW97	Gene names	Bat1, Bat1a, Uap56
Domain Architecture	No domain graphic available
Description	Spliceosome RNA helicase Bat1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (HLA-B-associated transcript 1).

DDX5_HUMAN
θ value	0.00665767 (rank : 60)	NC score	0.430154 (rank : 46)
Query Neighborhood Hits	210	Target Neighborhood Hits	102	Shared Neighborhood Hits	78
SwissProt Accessions	P17844, O75681	Gene names	DDX5, HELR, HLR1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68).

DDX5_MOUSE
θ value	0.00665767 (rank : 61)	NC score	0.430082 (rank : 47)
Query Neighborhood Hits	210	Target Neighborhood Hits	101	Shared Neighborhood Hits	78
SwissProt Accessions	Q61656	Gene names	Ddx5, Tnz2
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68) (DEAD box RNA helicase DEAD1) (mDEAD1).

DDX6_HUMAN
θ value	0.00665767 (rank : 62)	NC score	0.427140 (rank : 53)
Query Neighborhood Hits	210	Target Neighborhood Hits	97	Shared Neighborhood Hits	80
SwissProt Accessions	P26196	Gene names	DDX6, HLR2, RCK
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK).

DDX6_MOUSE
θ value	0.00665767 (rank : 63)	NC score	0.426804 (rank : 54)
Query Neighborhood Hits	210	Target Neighborhood Hits	98	Shared Neighborhood Hits	80
SwissProt Accessions	P54823	Gene names	Ddx6, Hlr2, Rck
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK homolog).

DDX47_HUMAN
θ value	0.00869519 (rank : 64)	NC score	0.435722 (rank : 40)
Query Neighborhood Hits	210	Target Neighborhood Hits	97	Shared Neighborhood Hits	80
SwissProt Accessions	Q9H0S4, Q96GM0, Q96NV8	Gene names	DDX47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX47_MOUSE
θ value	0.00869519 (rank : 65)	NC score	0.435545 (rank : 41)
Query Neighborhood Hits	210	Target Neighborhood Hits	97	Shared Neighborhood Hits	80
SwissProt Accessions	Q9CWX9	Gene names	Ddx47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX55_MOUSE
θ value	0.0113563 (rank : 66)	NC score	0.425741 (rank : 56)
Query Neighborhood Hits	210	Target Neighborhood Hits	111	Shared Neighborhood Hits	79
SwissProt Accessions	Q6ZPL9, Q149H5, Q3U460, Q8BZR1	Gene names	Ddx55, Kiaa1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX46_HUMAN
θ value	0.0148317 (rank : 67)	NC score	0.427712 (rank : 51)
Query Neighborhood Hits	210	Target Neighborhood Hits	357	Shared Neighborhood Hits	96
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

DDX46_MOUSE
θ value	0.0148317 (rank : 68)	NC score	0.426465 (rank : 55)
Query Neighborhood Hits	210	Target Neighborhood Hits	358	Shared Neighborhood Hits	95
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

DDX20_HUMAN
θ value	0.0252991 (rank : 69)	NC score	0.410048 (rank : 69)
Query Neighborhood Hits	210	Target Neighborhood Hits	121	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UHI6, Q96F72, Q9NVM3, Q9UF59, Q9UIY0, Q9Y659	Gene names	DDX20, DP103, GEMIN3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3).

DDX20_MOUSE
θ value	0.0330416 (rank : 70)	NC score	0.410098 (rank : 68)
Query Neighborhood Hits	210	Target Neighborhood Hits	177	Shared Neighborhood Hits	80
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

DDX24_MOUSE
θ value	0.0330416 (rank : 71)	NC score	0.409796 (rank : 70)
Query Neighborhood Hits	210	Target Neighborhood Hits	147	Shared Neighborhood Hits	80
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

SMCA1_HUMAN
θ value	0.0330416 (rank : 72)	NC score	0.059842 (rank : 106)
Query Neighborhood Hits	210	Target Neighborhood Hits	105	Shared Neighborhood Hits	27
SwissProt Accessions	P28370, Q5JV41, Q5JV42	Gene names	SMARCA1, SNF2L, SNF2L1
Domain Architecture
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1).

DDX28_MOUSE
θ value	0.0431538 (rank : 73)	NC score	0.417300 (rank : 66)
Query Neighborhood Hits	210	Target Neighborhood Hits	112	Shared Neighborhood Hits	84
SwissProt Accessions	Q9CWT6, Q3TQM0	Gene names	Ddx28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

U520_HUMAN
θ value	0.0431538 (rank : 74)	NC score	0.194200 (rank : 88)
Query Neighborhood Hits	210	Target Neighborhood Hits	88	Shared Neighborhood Hits	42
SwissProt Accessions	O75643, O94884, Q6PX59, Q96IF2, Q9H7S0	Gene names	ASCC3L1, HELIC2, KIAA0788
Domain Architecture	No domain graphic available
Description	U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.1.-) (U5 snRNP-specific 200 kDa protein) (U5-200KD) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog).

ANR12_HUMAN
θ value	0.0563607 (rank : 75)	NC score	0.031073 (rank : 149)
Query Neighborhood Hits	210	Target Neighborhood Hits	1081	Shared Neighborhood Hits	53
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

CHD5_HUMAN
θ value	0.0563607 (rank : 76)	NC score	0.076317 (rank : 93)
Query Neighborhood Hits	210	Target Neighborhood Hits	349	Shared Neighborhood Hits	40
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

CTR9_MOUSE
θ value	0.0563607 (rank : 77)	NC score	0.063350 (rank : 101)
Query Neighborhood Hits	210	Target Neighborhood Hits	427	Shared Neighborhood Hits	25
SwissProt Accessions	Q62018, Q3UFF5, Q3UY40, Q66JX4, Q7TPS6, Q8BND9, Q8BRD1, Q8C9W7, Q8C9Y3, Q8CHI1	Gene names	Ctr9, Kiaa0155, Sh2bp1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) (Tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa) (TPR-containing, SH2-binding phosphoprotein of 150 kDa) (p150TSP).

DDX24_HUMAN
θ value	0.0563607 (rank : 78)	NC score	0.407673 (rank : 71)
Query Neighborhood Hits	210	Target Neighborhood Hits	190	Shared Neighborhood Hits	83
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

WDHD1_MOUSE
θ value	0.0563607 (rank : 79)	NC score	0.036317 (rank : 135)
Query Neighborhood Hits	210	Target Neighborhood Hits	414	Shared Neighborhood Hits	15
SwissProt Accessions	P59328, Q6P408	Gene names	Wdhd1, And1
Domain Architecture	No domain graphic available
Description	WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA- binding protein 1) (And-1).

DDX1_HUMAN
θ value	0.0736092 (rank : 80)	NC score	0.399812 (rank : 73)
Query Neighborhood Hits	210	Target Neighborhood Hits	110	Shared Neighborhood Hits	74
SwissProt Accessions	Q92499	Gene names	DDX1
Domain Architecture
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB).

DDX1_MOUSE
θ value	0.0736092 (rank : 81)	NC score	0.400314 (rank : 72)
Query Neighborhood Hits	210	Target Neighborhood Hits	112	Shared Neighborhood Hits	75
SwissProt Accessions	Q91VR5, Q3TU41	Gene names	Ddx1
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1).

NOL8_HUMAN
θ value	0.0736092 (rank : 82)	NC score	0.056845 (rank : 108)
Query Neighborhood Hits	210	Target Neighborhood Hits	297	Shared Neighborhood Hits	28
SwissProt Accessions	Q76FK4, Q5TCC7, Q5TCC8, Q5TCD3, Q5TCD5, Q5TCD6, Q5TCD7, Q76D35, Q7L3E2, Q9H586, Q9H795, Q9H7W7, Q9H9J6, Q9NWA4, Q9NWM4	Gene names	NOL8, NOP132
Domain Architecture	No domain graphic available
Description	Nucleolar protein 8 (Nucleolar protein Nop132).

RPGR_MOUSE
θ value	0.0961366 (rank : 83)	NC score	0.037041 (rank : 132)
Query Neighborhood Hits	210	Target Neighborhood Hits	281	Shared Neighborhood Hits	22
SwissProt Accessions	Q9R0X5, O88408, Q9CU92	Gene names	Rpgr
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator (mRpgr).

BTAF1_HUMAN
θ value	0.125558 (rank : 84)	NC score	0.072691 (rank : 94)
Query Neighborhood Hits	210	Target Neighborhood Hits	97	Shared Neighborhood Hits	19
SwissProt Accessions	O14981, O43578	Gene names	BTAF1, TAF172
Domain Architecture
Description	TATA-binding protein-associated factor 172 (EC 3.6.1.-) (ATP-dependent helicase BTAF1) (TBP-associated factor 172) (TAF-172) (TAF(II)170) (B- TFIID transcription factor-associated 170 kDa subunit).

DDX55_HUMAN
θ value	0.125558 (rank : 85)	NC score	0.421830 (rank : 61)
Query Neighborhood Hits	210	Target Neighborhood Hits	122	Shared Neighborhood Hits	78
SwissProt Accessions	Q8NHQ9, Q658L6, Q9HCH7	Gene names	DDX55, KIAA1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DMD_HUMAN
θ value	0.125558 (rank : 86)	NC score	0.030631 (rank : 153)
Query Neighborhood Hits	210	Target Neighborhood Hits	1135	Shared Neighborhood Hits	33
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

DMD_MOUSE
θ value	0.125558 (rank : 87)	NC score	0.029779 (rank : 158)
Query Neighborhood Hits	210	Target Neighborhood Hits	1111	Shared Neighborhood Hits	38
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

CLSPN_HUMAN
θ value	0.163984 (rank : 88)	NC score	0.061797 (rank : 102)
Query Neighborhood Hits	210	Target Neighborhood Hits	433	Shared Neighborhood Hits	33
SwissProt Accessions	Q9HAW4, Q5VYG0, Q6P6H5, Q8IWI1	Gene names	CLSPN
Domain Architecture	No domain graphic available
Description	Claspin (hClaspin) (Hu-Claspin).

CTR9_HUMAN
θ value	0.163984 (rank : 89)	NC score	0.058607 (rank : 107)
Query Neighborhood Hits	210	Target Neighborhood Hits	383	Shared Neighborhood Hits	18
SwissProt Accessions	Q6PD62, Q15015	Gene names	CTR9, KIAA0155, SH2BP1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1).

DDX53_HUMAN
θ value	0.163984 (rank : 90)	NC score	0.414484 (rank : 67)
Query Neighborhood Hits	210	Target Neighborhood Hits	124	Shared Neighborhood Hits	76
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

MDM2_HUMAN
θ value	0.163984 (rank : 91)	NC score	0.041645 (rank : 127)
Query Neighborhood Hits	210	Target Neighborhood Hits	92	Shared Neighborhood Hits	6
SwissProt Accessions	Q00987, Q13226, Q13297, Q13298, Q13299, Q13300, Q13301, Q53XW0, Q71TW9, Q9UGI3, Q9UMT8	Gene names	MDM2
Domain Architecture
Description	Ubiquitin-protein ligase E3 Mdm2 (EC 6.3.2.-) (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein) (Hdm2).

RECQ4_HUMAN
θ value	0.163984 (rank : 92)	NC score	0.278510 (rank : 79)
Query Neighborhood Hits	210	Target Neighborhood Hits	177	Shared Neighborhood Hits	80
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

RXINP_MOUSE
θ value	0.279714 (rank : 93)	NC score	0.043969 (rank : 125)
Query Neighborhood Hits	210	Target Neighborhood Hits	99	Shared Neighborhood Hits	8
SwissProt Accessions	Q5U5Q9, Q60811	Gene names	Rxrip110, Rip110
Domain Architecture	No domain graphic available
Description	Retinoid X receptor-interacting protein 110.

SMC4_MOUSE
θ value	0.279714 (rank : 94)	NC score	0.027695 (rank : 163)
Query Neighborhood Hits	210	Target Neighborhood Hits	830	Shared Neighborhood Hits	33
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

SYNE2_HUMAN
θ value	0.279714 (rank : 95)	NC score	0.030664 (rank : 152)
Query Neighborhood Hits	210	Target Neighborhood Hits	1323	Shared Neighborhood Hits	52
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

AQR_HUMAN
θ value	0.365318 (rank : 96)	NC score	0.067107 (rank : 99)
Query Neighborhood Hits	210	Target Neighborhood Hits	88	Shared Neighborhood Hits	7
SwissProt Accessions	O60306, Q2YDX9, Q6IRU8, Q6PIC8	Gene names	AQR, KIAA0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius (Intron-binding protein of 160 kDa) (IBP160).

AQR_MOUSE
θ value	0.365318 (rank : 97)	NC score	0.069223 (rank : 97)
Query Neighborhood Hits	210	Target Neighborhood Hits	62	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CFQ3, P97871, Q3U9N1, Q3ULE8, Q80TX8	Gene names	Aqr, Kiaa0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius.

GCF_HUMAN
θ value	0.365318 (rank : 98)	NC score	0.046766 (rank : 123)
Query Neighborhood Hits	210	Target Neighborhood Hits	107	Shared Neighborhood Hits	9
SwissProt Accessions	P16383, O95032	Gene names	TCF9, C2orf3
Domain Architecture	No domain graphic available
Description	GC-rich sequence DNA-binding factor (GCF) (Transcription factor 9) (TCF-9).

ATRX_HUMAN
θ value	0.47712 (rank : 99)	NC score	0.078195 (rank : 92)
Query Neighborhood Hits	210	Target Neighborhood Hits	842	Shared Neighborhood Hits	68
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

BCAS1_MOUSE
θ value	0.47712 (rank : 100)	NC score	0.036942 (rank : 133)
Query Neighborhood Hits	210	Target Neighborhood Hits	215	Shared Neighborhood Hits	7
SwissProt Accessions	Q80YN3, Q9CVA1	Gene names	Bcas1, Nabc1
Domain Architecture	No domain graphic available
Description	Breast carcinoma amplified sequence 1 homolog (Novel amplified in breast cancer 1 homolog).

NBR1_HUMAN
θ value	0.47712 (rank : 101)	NC score	0.034555 (rank : 140)
Query Neighborhood Hits	210	Target Neighborhood Hits	105	Shared Neighborhood Hits	5
SwissProt Accessions	Q14596, Q13173, Q15026, Q96GB6, Q9NRF7	Gene names	NBR1, 1A13B, KIAA0049, M17S2
Domain Architecture
Description	Next to BRCA1 gene 1 protein (Neighbor of BRCA1 gene 1 protein) (Membrane component, chromosome 17, surface marker 2) (1A1-3B).

PKCB1_HUMAN
θ value	0.47712 (rank : 102)	NC score	0.047214 (rank : 122)
Query Neighborhood Hits	210	Target Neighborhood Hits	488	Shared Neighborhood Hits	33
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

ATRX_MOUSE
θ value	0.62314 (rank : 103)	NC score	0.071435 (rank : 96)
Query Neighborhood Hits	210	Target Neighborhood Hits	682	Shared Neighborhood Hits	55
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

CD2L7_HUMAN
θ value	0.62314 (rank : 104)	NC score	0.000299 (rank : 222)
Query Neighborhood Hits	210	Target Neighborhood Hits	1275	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

DZIP3_MOUSE
θ value	0.62314 (rank : 105)	NC score	0.030086 (rank : 156)
Query Neighborhood Hits	210	Target Neighborhood Hits	414	Shared Neighborhood Hits	23
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

GOGB1_HUMAN
θ value	0.62314 (rank : 106)	NC score	0.027432 (rank : 164)
Query Neighborhood Hits	210	Target Neighborhood Hits	2297	Shared Neighborhood Hits	73
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

MACOI_HUMAN
θ value	0.62314 (rank : 107)	NC score	0.034142 (rank : 142)
Query Neighborhood Hits	210	Target Neighborhood Hits	650	Shared Neighborhood Hits	29
SwissProt Accessions	Q8N5G2, Q2TLX5, Q2TLX6, Q9NVG6	Gene names	TMEM57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57).

RAD54_MOUSE
θ value	0.62314 (rank : 108)	NC score	0.060946 (rank : 104)
Query Neighborhood Hits	210	Target Neighborhood Hits	51	Shared Neighborhood Hits	17
SwissProt Accessions	P70270, Q8BSR5, Q8C2C4, Q8K3D4	Gene names	Rad54l, Rad54
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (mRAD54) (mHR54).

SETX_HUMAN
θ value	0.62314 (rank : 109)	NC score	0.040398 (rank : 128)
Query Neighborhood Hits	210	Target Neighborhood Hits	368	Shared Neighborhood Hits	25
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

SFRS4_MOUSE
θ value	0.62314 (rank : 110)	NC score	0.020644 (rank : 177)
Query Neighborhood Hits	210	Target Neighborhood Hits	406	Shared Neighborhood Hits	17
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

TEX14_MOUSE
θ value	0.62314 (rank : 111)	NC score	0.013255 (rank : 199)
Query Neighborhood Hits	210	Target Neighborhood Hits	1333	Shared Neighborhood Hits	38
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

UBP28_HUMAN
θ value	0.62314 (rank : 112)	NC score	0.031102 (rank : 148)
Query Neighborhood Hits	210	Target Neighborhood Hits	117	Shared Neighborhood Hits	6
SwissProt Accessions	Q96RU2, Q9P213	Gene names	USP28, KIAA1515
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

DNJC1_HUMAN
θ value	0.813845 (rank : 113)	NC score	0.023771 (rank : 169)
Query Neighborhood Hits	210	Target Neighborhood Hits	127	Shared Neighborhood Hits	5
SwissProt Accessions	Q96KC8	Gene names	DNAJC1
Domain Architecture
Description	DnaJ homolog subfamily C member 1.

IF2P_HUMAN
θ value	0.813845 (rank : 114)	NC score	0.035585 (rank : 137)
Query Neighborhood Hits	210	Target Neighborhood Hits	889	Shared Neighborhood Hits	46
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

NKTR_HUMAN
θ value	0.813845 (rank : 115)	NC score	0.035029 (rank : 138)
Query Neighborhood Hits	210	Target Neighborhood Hits	658	Shared Neighborhood Hits	49
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

RAD54_HUMAN
θ value	0.813845 (rank : 116)	NC score	0.059984 (rank : 105)
Query Neighborhood Hits	210	Target Neighborhood Hits	51	Shared Neighborhood Hits	16
SwissProt Accessions	Q92698, Q6IUY3	Gene names	RAD54L, RAD54A
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (hRAD54) (hHR54).

RECQ5_HUMAN
θ value	0.813845 (rank : 117)	NC score	0.223772 (rank : 84)
Query Neighborhood Hits	210	Target Neighborhood Hits	390	Shared Neighborhood Hits	74
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

SGOL2_HUMAN
θ value	0.813845 (rank : 118)	NC score	0.036469 (rank : 134)
Query Neighborhood Hits	210	Target Neighborhood Hits	207	Shared Neighborhood Hits	16
SwissProt Accessions	Q562F6, Q53RR9, Q53T20, Q86XY4, Q8IWK2, Q8IZK1, Q8N1Q5, Q96LQ3	Gene names	SGOL2
Domain Architecture	No domain graphic available
Description	Shugoshin-like 2 (Tripin).

UBP28_MOUSE
θ value	0.813845 (rank : 119)	NC score	0.029591 (rank : 159)
Query Neighborhood Hits	210	Target Neighborhood Hits	178	Shared Neighborhood Hits	6
SwissProt Accessions	Q5I043, Q6NZP3, Q6ZPP1, Q8BWI1	Gene names	Usp28, Kiaa1515
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

NUF2_MOUSE
θ value	1.06291 (rank : 120)	NC score	0.029893 (rank : 157)
Query Neighborhood Hits	210	Target Neighborhood Hits	585	Shared Neighborhood Hits	25
SwissProt Accessions	Q99P69, Q8BTK7, Q8VE05, Q9CST5	Gene names	Cdca1, Nuf2r
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (Cell division cycle-associated protein 1).

SMCA2_HUMAN
θ value	1.06291 (rank : 121)	NC score	0.052490 (rank : 114)
Query Neighborhood Hits	210	Target Neighborhood Hits	503	Shared Neighborhood Hits	37
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

UBE3A_HUMAN
θ value	1.06291 (rank : 122)	NC score	0.012739 (rank : 201)
Query Neighborhood Hits	210	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	Q05086, P78355, Q93066, Q9UEP4, Q9UEP5, Q9UEP6, Q9UEP7, Q9UEP8, Q9UEP9	Gene names	UBE3A, E6AP
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (E6AP ubiquitin-protein ligase) (Oncogenic protein-associated protein E6-AP) (Human papillomavirus E6-associated protein) (NY-REN-54 antigen).

AF9_HUMAN
θ value	1.38821 (rank : 123)	NC score	0.038688 (rank : 129)
Query Neighborhood Hits	210	Target Neighborhood Hits	202	Shared Neighborhood Hits	16
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

ANK2_HUMAN
θ value	1.38821 (rank : 124)	NC score	0.012852 (rank : 200)
Query Neighborhood Hits	210	Target Neighborhood Hits	1615	Shared Neighborhood Hits	50
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

CHD8_HUMAN
θ value	1.38821 (rank : 125)	NC score	0.047662 (rank : 121)
Query Neighborhood Hits	210	Target Neighborhood Hits	235	Shared Neighborhood Hits	28
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

CIR_MOUSE
θ value	1.38821 (rank : 126)	NC score	0.037300 (rank : 131)
Query Neighborhood Hits	210	Target Neighborhood Hits	255	Shared Neighborhood Hits	21
SwissProt Accessions	Q9DA19, Q3V2N9, Q4KL44, Q52KL9, Q5FW66	Gene names	Cir
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor.

ITA3_MOUSE
θ value	1.38821 (rank : 127)	NC score	0.010572 (rank : 205)
Query Neighborhood Hits	210	Target Neighborhood Hits	54	Shared Neighborhood Hits	2
SwissProt Accessions	Q62470, Q08441, Q08442	Gene names	Itga3
Domain Architecture
Description	Integrin alpha-3 precursor (Galactoprotein B3) (GAPB3) (VLA-3 alpha chain) (CD49c antigen) [Contains: Integrin alpha-3 heavy chain; Integrin alpha-3 light chain].

IWS1_MOUSE
θ value	1.38821 (rank : 128)	NC score	0.044559 (rank : 124)
Query Neighborhood Hits	210	Target Neighborhood Hits	1258	Shared Neighborhood Hits	64
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

CAN3_HUMAN
θ value	1.81305 (rank : 129)	NC score	0.008968 (rank : 211)
Query Neighborhood Hits	210	Target Neighborhood Hits	96	Shared Neighborhood Hits	3
SwissProt Accessions	P20807, Q9BTU4, Q9Y5S6, Q9Y5S7	Gene names	CAPN3, CANP3, CANPL3, NCL1
Domain Architecture
Description	Calpain-3 (EC 3.4.22.-) (Calpain L3) (Calpain p94) (Calcium-activated neutral proteinase 3) (CANP 3) (Muscle-specific calcium-activated neutral protease 3) (nCL-1).

CCD39_MOUSE
θ value	1.81305 (rank : 130)	NC score	0.021143 (rank : 174)
Query Neighborhood Hits	210	Target Neighborhood Hits	1026	Shared Neighborhood Hits	36
SwissProt Accessions	Q9D5Y1, Q8CDG6	Gene names	Ccdc39, D3Ertd789e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

CCNB3_HUMAN
θ value	1.81305 (rank : 131)	NC score	0.043572 (rank : 126)
Query Neighborhood Hits	210	Target Neighborhood Hits	368	Shared Neighborhood Hits	30
SwissProt Accessions	Q8WWL7, Q96SB5, Q96SB6, Q96SB7, Q9NT38	Gene names	CCNB3, CYCB3
Domain Architecture
Description	G2/mitotic-specific cyclin-B3.

CUTL1_MOUSE
θ value	1.81305 (rank : 132)	NC score	0.019612 (rank : 179)
Query Neighborhood Hits	210	Target Neighborhood Hits	1620	Shared Neighborhood Hits	48
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

GSH1_MOUSE
θ value	1.81305 (rank : 133)	NC score	0.025554 (rank : 167)
Query Neighborhood Hits	210	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	P97494, O09166, Q8VCS5	Gene names	Gclc, Glclc
Domain Architecture
Description	Glutamate--cysteine ligase catalytic subunit (EC 6.3.2.2) (Gamma- glutamylcysteine synthetase) (Gamma-ECS) (GCS heavy chain).

MACOI_MOUSE
θ value	1.81305 (rank : 134)	NC score	0.030604 (rank : 154)
Query Neighborhood Hits	210	Target Neighborhood Hits	620	Shared Neighborhood Hits	26
SwissProt Accessions	Q7TQE6	Gene names	Tmem57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57) (Brain-specific adaptor protein C61).

PHF3_HUMAN
θ value	1.81305 (rank : 135)	NC score	0.029268 (rank : 161)
Query Neighborhood Hits	210	Target Neighborhood Hits	419	Shared Neighborhood Hits	24
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

RFC1_HUMAN
θ value	1.81305 (rank : 136)	NC score	0.033432 (rank : 144)
Query Neighborhood Hits	210	Target Neighborhood Hits	352	Shared Neighborhood Hits	23
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

WRN_HUMAN
θ value	1.81305 (rank : 137)	NC score	0.208797 (rank : 85)
Query Neighborhood Hits	210	Target Neighborhood Hits	132	Shared Neighborhood Hits	79
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

XRCC1_MOUSE
θ value	1.81305 (rank : 138)	NC score	0.026358 (rank : 165)
Query Neighborhood Hits	210	Target Neighborhood Hits	242	Shared Neighborhood Hits	8
SwissProt Accessions	Q60596, Q3THC5, Q5U435, Q7TNQ5	Gene names	Xrcc1, Xrcc-1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

BAZ2A_MOUSE
θ value	2.36792 (rank : 139)	NC score	0.020914 (rank : 175)
Query Neighborhood Hits	210	Target Neighborhood Hits	744	Shared Neighborhood Hits	33
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

CENPE_HUMAN
θ value	2.36792 (rank : 140)	NC score	0.022075 (rank : 171)
Query Neighborhood Hits	210	Target Neighborhood Hits	2060	Shared Neighborhood Hits	69
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

CJ068_HUMAN
θ value	2.36792 (rank : 141)	NC score	0.037736 (rank : 130)
Query Neighborhood Hits	210	Target Neighborhood Hits	316	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H943, Q8N7T7	Gene names	C10orf68
Domain Architecture	No domain graphic available
Description	Protein C10orf68.

GP112_HUMAN
θ value	2.36792 (rank : 142)	NC score	0.008007 (rank : 213)
Query Neighborhood Hits	210	Target Neighborhood Hits	441	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

IWS1_HUMAN
θ value	2.36792 (rank : 143)	NC score	0.052316 (rank : 115)
Query Neighborhood Hits	210	Target Neighborhood Hits	1241	Shared Neighborhood Hits	63
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

LUC7L_HUMAN
θ value	2.36792 (rank : 144)	NC score	0.034193 (rank : 141)
Query Neighborhood Hits	210	Target Neighborhood Hits	130	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NQ29, Q96S32, Q9NPH4	Gene names	LUC7L, LUC7L1
Domain Architecture
Description	Putative RNA-binding protein Luc7-like 1 (SR+89) (Putative SR protein LUC7B1).

LUC7L_MOUSE
θ value	2.36792 (rank : 145)	NC score	0.034683 (rank : 139)
Query Neighborhood Hits	210	Target Neighborhood Hits	111	Shared Neighborhood Hits	12
SwissProt Accessions	Q9CYI4, Q8K247, Q9CWM1	Gene names	Luc7l
Domain Architecture
Description	Putative RNA-binding protein Luc7-like 1.

MAGC1_HUMAN
θ value	2.36792 (rank : 146)	NC score	0.010512 (rank : 206)
Query Neighborhood Hits	210	Target Neighborhood Hits	431	Shared Neighborhood Hits	13
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

MYT1_HUMAN
θ value	2.36792 (rank : 147)	NC score	0.016292 (rank : 188)
Query Neighborhood Hits	210	Target Neighborhood Hits	475	Shared Neighborhood Hits	24
SwissProt Accessions	Q01538, O94922, Q9UPV2	Gene names	MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1
Domain Architecture
Description	Myelin transcription factor 1 (MyT1) (MyTI) (Proteolipid protein- binding protein) (PLPB1).

NOL7_HUMAN
θ value	2.36792 (rank : 148)	NC score	0.033786 (rank : 143)
Query Neighborhood Hits	210	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UMY1, Q5T297, Q9Y3U7	Gene names	NOL7, C6orf90, NOP27
Domain Architecture	No domain graphic available
Description	Nucleolar protein 7 (Nucleolar protein of 27 kDa).

RASF5_MOUSE
θ value	2.36792 (rank : 149)	NC score	0.016271 (rank : 189)
Query Neighborhood Hits	210	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	Q5EBH1, O70407, Q6KAR0, Q8C2E8	Gene names	Rassf5, Nore1, Rapl
Domain Architecture	No domain graphic available
Description	Ras association domain-containing family protein 5 (New ras effector 1) (Regulator for cell adhesion and polarization enriched in lymphoid tissues) (RAPL).

UBXD6_MOUSE
θ value	2.36792 (rank : 150)	NC score	0.029037 (rank : 162)
Query Neighborhood Hits	210	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QZ49	Gene names	Ubxd6, D0H8S2298E, Rep8
Domain Architecture	No domain graphic available
Description	UBX domain-containing protein 6 (Reproduction 8 protein) (Protein Rep- 8).

ZFAN3_MOUSE
θ value	2.36792 (rank : 151)	NC score	0.026273 (rank : 166)
Query Neighborhood Hits	210	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q497H0, Q8K230, Q8R2V7, Q8R3V1	Gene names	Zfand3, Tex27
Domain Architecture	No domain graphic available
Description	AN1-type zinc finger protein 3 (Testis-expressed sequence 27).

ATAD2_MOUSE
θ value	3.0926 (rank : 152)	NC score	0.009243 (rank : 209)
Query Neighborhood Hits	210	Target Neighborhood Hits	167	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CDM1	Gene names	Atad2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

BRCA1_HUMAN
θ value	3.0926 (rank : 153)	NC score	0.012171 (rank : 202)
Query Neighborhood Hits	210	Target Neighborhood Hits	381	Shared Neighborhood Hits	10
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

FLIP1_HUMAN
θ value	3.0926 (rank : 154)	NC score	0.020526 (rank : 178)
Query Neighborhood Hits	210	Target Neighborhood Hits	1405	Shared Neighborhood Hits	48
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

GOGA1_HUMAN
θ value	3.0926 (rank : 155)	NC score	0.017774 (rank : 184)
Query Neighborhood Hits	210	Target Neighborhood Hits	1222	Shared Neighborhood Hits	44
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

HMMR_MOUSE
θ value	3.0926 (rank : 156)	NC score	0.019388 (rank : 180)
Query Neighborhood Hits	210	Target Neighborhood Hits	1178	Shared Neighborhood Hits	46
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

NOLC1_HUMAN
θ value	3.0926 (rank : 157)	NC score	0.033236 (rank : 145)
Query Neighborhood Hits	210	Target Neighborhood Hits	452	Shared Neighborhood Hits	25
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

RAD1_MOUSE
θ value	3.0926 (rank : 158)	NC score	0.024200 (rank : 168)
Query Neighborhood Hits	210	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QWZ1, O70452, O88391, Q3TGU1, Q3UG66, Q9QWZ3	Gene names	Rad1, Rec1
Domain Architecture	No domain graphic available
Description	Cell cycle checkpoint protein RAD1 (EC 3.1.11.2) (DNA repair exonuclease rad1 homolog) (Rad1-like DNA damage checkpoint protein) (mRAD1).

SRRM2_MOUSE
θ value	3.0926 (rank : 159)	NC score	0.021857 (rank : 173)
Query Neighborhood Hits	210	Target Neighborhood Hits	1470	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

ANKS1_MOUSE
θ value	4.03905 (rank : 160)	NC score	0.006787 (rank : 214)
Query Neighborhood Hits	210	Target Neighborhood Hits	453	Shared Neighborhood Hits	7
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

CHD3_HUMAN
θ value	4.03905 (rank : 161)	NC score	0.069208 (rank : 98)
Query Neighborhood Hits	210	Target Neighborhood Hits	397	Shared Neighborhood Hits	42
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

CUTL1_HUMAN
θ value	4.03905 (rank : 162)	NC score	0.018952 (rank : 181)
Query Neighborhood Hits	210	Target Neighborhood Hits	1574	Shared Neighborhood Hits	48
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

DMP1_MOUSE
θ value	4.03905 (rank : 163)	NC score	0.035660 (rank : 136)
Query Neighborhood Hits	210	Target Neighborhood Hits	498	Shared Neighborhood Hits	31
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

DSPP_HUMAN
θ value	4.03905 (rank : 164)	NC score	0.029312 (rank : 160)
Query Neighborhood Hits	210	Target Neighborhood Hits	645	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

MSH6_HUMAN
θ value	4.03905 (rank : 165)	NC score	0.014410 (rank : 196)
Query Neighborhood Hits	210	Target Neighborhood Hits	81	Shared Neighborhood Hits	8
SwissProt Accessions	P52701, O43706, O43917, Q8TCX4, Q9BTB5	Gene names	MSH6, GTBP
Domain Architecture
Description	DNA mismatch repair protein MSH6 (MutS-alpha 160 kDa subunit) (G/T mismatch-binding protein) (GTBP) (GTMBP) (p160).

MTF1_HUMAN
θ value	4.03905 (rank : 166)	NC score	-0.004088 (rank : 225)
Query Neighborhood Hits	210	Target Neighborhood Hits	814	Shared Neighborhood Hits	5
SwissProt Accessions	Q14872, Q96CB1	Gene names	MTF1
Domain Architecture	No domain graphic available
Description	Metal-regulatory transcription factor 1 (Transcription factor MTF-1) (MRE-binding transcription factor).

NIN_HUMAN
θ value	4.03905 (rank : 167)	NC score	0.018826 (rank : 182)
Query Neighborhood Hits	210	Target Neighborhood Hits	1416	Shared Neighborhood Hits	43
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

RBCC1_MOUSE
θ value	4.03905 (rank : 168)	NC score	0.020874 (rank : 176)
Query Neighborhood Hits	210	Target Neighborhood Hits	1048	Shared Neighborhood Hits	38
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

ZCH11_HUMAN
θ value	4.03905 (rank : 169)	NC score	0.030736 (rank : 151)
Query Neighborhood Hits	210	Target Neighborhood Hits	278	Shared Neighborhood Hits	23
SwissProt Accessions	Q5TAX3, Q12764, Q5TAX4, Q86XZ3	Gene names	ZCCHC11, KIAA0191
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 11.

ARHG6_MOUSE
θ value	5.27518 (rank : 170)	NC score	0.006237 (rank : 215)
Query Neighborhood Hits	210	Target Neighborhood Hits	394	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

ATX7_HUMAN
θ value	5.27518 (rank : 171)	NC score	0.015218 (rank : 193)
Query Neighborhood Hits	210	Target Neighborhood Hits	351	Shared Neighborhood Hits	8
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

C102B_HUMAN
θ value	5.27518 (rank : 172)	NC score	0.021882 (rank : 172)
Query Neighborhood Hits	210	Target Neighborhood Hits	542	Shared Neighborhood Hits	26
SwissProt Accessions	Q68D86, Q7Z467, Q8NDK7, Q9H5C1	Gene names	CCDC102B, C18orf14
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 102B.

GP137_HUMAN
θ value	5.27518 (rank : 173)	NC score	0.016781 (rank : 185)
Query Neighborhood Hits	210	Target Neighborhood Hits	119	Shared Neighborhood Hits	8
SwissProt Accessions	Q14444, Q15074	Gene names	M11S1, GPIP137
Domain Architecture	No domain graphic available
Description	GPI-anchored protein p137 (p137GPI) (Membrane component chromosome 11 surface marker 1).

JARD2_MOUSE
θ value	5.27518 (rank : 174)	NC score	0.015246 (rank : 192)
Query Neighborhood Hits	210	Target Neighborhood Hits	169	Shared Neighborhood Hits	10
SwissProt Accessions	Q62315, Q99LD1	Gene names	Jarid2, Jmj
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

KI13A_HUMAN
θ value	5.27518 (rank : 175)	NC score	0.005678 (rank : 217)
Query Neighborhood Hits	210	Target Neighborhood Hits	359	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H1H9, Q9H1H8	Gene names	KIF13A, RBKIN
Domain Architecture
Description	Kinesin-like protein KIF13A (Kinesin-like protein RBKIN).

LC7L2_HUMAN
θ value	5.27518 (rank : 176)	NC score	0.030093 (rank : 155)
Query Neighborhood Hits	210	Target Neighborhood Hits	235	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y383, Q8IUP9, Q9NVL3, Q9NVN7, Q9UQN1	Gene names	LUC7L2
Domain Architecture
Description	Putative RNA-binding protein Luc7-like 2.

LC7L2_MOUSE
θ value	5.27518 (rank : 177)	NC score	0.031038 (rank : 150)
Query Neighborhood Hits	210	Target Neighborhood Hits	244	Shared Neighborhood Hits	18
SwissProt Accessions	Q7TNC4, Q99LM5, Q99PC3	Gene names	Luc7l2
Domain Architecture
Description	Putative RNA-binding protein Luc7-like 2 (CGI-74 homolog).

MAST1_HUMAN
θ value	5.27518 (rank : 178)	NC score	-0.003821 (rank : 224)
Query Neighborhood Hits	210	Target Neighborhood Hits	1146	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MYO10_HUMAN
θ value	5.27518 (rank : 179)	NC score	0.004788 (rank : 218)
Query Neighborhood Hits	210	Target Neighborhood Hits	920	Shared Neighborhood Hits	28
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

SMRCD_HUMAN
θ value	5.27518 (rank : 180)	NC score	0.049047 (rank : 120)
Query Neighborhood Hits	210	Target Neighborhood Hits	117	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H4L7, Q96SX1, Q9H017, Q9H860, Q9NPU9, Q9ULU7	Gene names	SMARCAD1, KIAA1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase 1) (hHEL1).

SMRCD_MOUSE
θ value	5.27518 (rank : 181)	NC score	0.049260 (rank : 119)
Query Neighborhood Hits	210	Target Neighborhood Hits	96	Shared Neighborhood Hits	24
SwissProt Accessions	Q04692	Gene names	Smarcad1, Etl1, Kiaa1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase SMARCAD1) (Enhancer trap locus homolog 1) (Etl-1).

TLR4_MOUSE
θ value	5.27518 (rank : 182)	NC score	0.002803 (rank : 220)
Query Neighborhood Hits	210	Target Neighborhood Hits	279	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QUK6, Q9D691, Q9QZF5, Q9Z203	Gene names	Tlr4, Lps
Domain Architecture
Description	Toll-like receptor 4 precursor (CD284 antigen).

AL2SE_HUMAN
θ value	6.88961 (rank : 183)	NC score	0.011144 (rank : 204)
Query Neighborhood Hits	210	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NDH6, Q53P45, Q53QZ4, Q53T97, Q96N47, Q96Q32, Q9BVQ2	Gene names	ALS2CR15
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 15 protein.

CCD41_MOUSE
θ value	6.88961 (rank : 184)	NC score	0.018661 (rank : 183)
Query Neighborhood Hits	210	Target Neighborhood Hits	1399	Shared Neighborhood Hits	57
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

CR030_HUMAN
θ value	6.88961 (rank : 185)	NC score	0.016070 (rank : 190)
Query Neighborhood Hits	210	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N787	Gene names	C18orf30
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf30.

DDX28_HUMAN
θ value	6.88961 (rank : 186)	NC score	0.388659 (rank : 74)
Query Neighborhood Hits	210	Target Neighborhood Hits	103	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NUL7	Gene names	DDX28, MDDX28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DNJC1_MOUSE
θ value	6.88961 (rank : 187)	NC score	0.015410 (rank : 191)
Query Neighborhood Hits	210	Target Neighborhood Hits	129	Shared Neighborhood Hits	4
SwissProt Accessions	Q61712	Gene names	Dnajc1, Dnajl1, Mtj1
Domain Architecture
Description	DnaJ homolog subfamily C member 1 (DnaJ protein homolog MTJ1).

GP152_HUMAN
θ value	6.88961 (rank : 188)	NC score	0.002543 (rank : 221)
Query Neighborhood Hits	210	Target Neighborhood Hits	636	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TDT2, Q86SM0	Gene names	GPR152, PGR5
Domain Architecture
Description	Probable G-protein coupled receptor 152 (G-protein coupled receptor PGR5).

K0146_MOUSE
θ value	6.88961 (rank : 189)	NC score	0.014605 (rank : 195)
Query Neighborhood Hits	210	Target Neighborhood Hits	57	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BGX7, Q3TCD0, Q5U457, Q6A0B6, Q6IS60, Q811E1, Q8BWD6, Q8R305	Gene names	Kiaa0146
Domain Architecture	No domain graphic available
Description	Protein KIAA0146.

KNTC2_MOUSE
θ value	6.88961 (rank : 190)	NC score	0.016368 (rank : 187)
Query Neighborhood Hits	210	Target Neighborhood Hits	692	Shared Neighborhood Hits	25
SwissProt Accessions	Q9D0F1, Q3TQT6, Q3UWM5, Q99P70	Gene names	Kntc2, Hec1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (Kinetochore-associated protein 2).

NEK4_HUMAN
θ value	6.88961 (rank : 191)	NC score	-0.004611 (rank : 227)
Query Neighborhood Hits	210	Target Neighborhood Hits	883	Shared Neighborhood Hits	6
SwissProt Accessions	P51957	Gene names	NEK4, STK2
Domain Architecture
Description	Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2) (Serine/threonine-protein kinase NRK2).

SMCA4_HUMAN
θ value	6.88961 (rank : 192)	NC score	0.049890 (rank : 118)
Query Neighborhood Hits	210	Target Neighborhood Hits	597	Shared Neighborhood Hits	44
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

WRN_MOUSE
θ value	6.88961 (rank : 193)	NC score	0.202054 (rank : 86)
Query Neighborhood Hits	210	Target Neighborhood Hits	295	Shared Neighborhood Hits	87
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

ZN638_MOUSE
θ value	6.88961 (rank : 194)	NC score	0.014968 (rank : 194)
Query Neighborhood Hits	210	Target Neighborhood Hits	318	Shared Neighborhood Hits	15
SwissProt Accessions	Q61464, Q6DFV9, Q8C941	Gene names	Znf638, Np220, Zfml
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein).

AKAP3_HUMAN
θ value	8.99809 (rank : 195)	NC score	0.008664 (rank : 212)
Query Neighborhood Hits	210	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	O75969, O75945, Q9UM61	Gene names	AKAP3, AKAP110, SOB1
Domain Architecture
Description	A-kinase anchor protein 3 (Protein kinase A-anchoring protein 3) (PRKA3) (A-kinase anchor protein 110 kDa) (AKAP 110) (Sperm oocyte- binding protein) (Fibrousheathin-1) (Fibrousheathin I) (Fibrous sheath protein of 95 kDa) (FSP95).

ANK3_HUMAN
θ value	8.99809 (rank : 196)	NC score	0.009690 (rank : 207)
Query Neighborhood Hits	210	Target Neighborhood Hits	853	Shared Neighborhood Hits	44
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

EVC_HUMAN
θ value	8.99809 (rank : 197)	NC score	0.013620 (rank : 198)
Query Neighborhood Hits	210	Target Neighborhood Hits	129	Shared Neighborhood Hits	10
SwissProt Accessions	P57679	Gene names	EVC
Domain Architecture	No domain graphic available
Description	Ellis-van Creveld syndrome protein (DWF-1).

EVI1_HUMAN
θ value	8.99809 (rank : 198)	NC score	-0.004400 (rank : 226)
Query Neighborhood Hits	210	Target Neighborhood Hits	924	Shared Neighborhood Hits	17
SwissProt Accessions	Q03112, Q16122, Q99917	Gene names	EVI1
Domain Architecture
Description	Ecotropic virus integration 1 site protein.

FGD5_MOUSE
θ value	8.99809 (rank : 199)	NC score	0.004078 (rank : 219)
Query Neighborhood Hits	210	Target Neighborhood Hits	170	Shared Neighborhood Hits	5
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

GCP4_HUMAN
θ value	8.99809 (rank : 200)	NC score	0.009234 (rank : 210)
Query Neighborhood Hits	210	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UGJ1, Q969X3, Q9NVF0	Gene names	TUBGCP4, 76P, GCP4
Domain Architecture
Description	Gamma-tubulin complex component 4 (GCP-4) (hGCP4) (h76p) (Hgrip76).

GRHL2_MOUSE
θ value	8.99809 (rank : 201)	NC score	0.005956 (rank : 216)
Query Neighborhood Hits	210	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K5C0, Q80UZ5	Gene names	Grhl2, Bom, Tcfcp2l3
Domain Architecture	No domain graphic available
Description	Grainyhead-like protein 2 homolog (Brother of mammalian grainyhead) (Transcription factor CP2-like 3).

RMI1_MOUSE
θ value	8.99809 (rank : 202)	NC score	0.011636 (rank : 203)
Query Neighborhood Hits	210	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D4G9, Q8C560, Q8CI20	Gene names	Rmi1
Domain Architecture	No domain graphic available
Description	Protein RMI1 homolog.

RPTN_MOUSE
θ value	8.99809 (rank : 203)	NC score	0.016731 (rank : 186)
Query Neighborhood Hits	210	Target Neighborhood Hits	650	Shared Neighborhood Hits	34
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

RRBP1_MOUSE
θ value	8.99809 (rank : 204)	NC score	0.023611 (rank : 170)
Query Neighborhood Hits	210	Target Neighborhood Hits	1650	Shared Neighborhood Hits	57
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

SK2L2_HUMAN
θ value	8.99809 (rank : 205)	NC score	0.032784 (rank : 147)
Query Neighborhood Hits	210	Target Neighborhood Hits	36	Shared Neighborhood Hits	12
SwissProt Accessions	P42285, Q8TAG2	Gene names	SKIV2L2, KIAA0052
Domain Architecture	No domain graphic available
Description	Superkiller viralicidic activity 2-like 2 (EC 3.6.1.-) (ATP-dependent helicase SKIV2L2).

SK2L2_MOUSE
θ value	8.99809 (rank : 206)	NC score	0.032946 (rank : 146)
Query Neighborhood Hits	210	Target Neighborhood Hits	45	Shared Neighborhood Hits	12
SwissProt Accessions	Q9CZU3	Gene names	Skiv2l2
Domain Architecture	No domain graphic available
Description	Superkiller viralicidic activity 2-like 2 (EC 3.6.1.-) (ATP-dependent helicase SKIV2L2).

THAP4_HUMAN
θ value	8.99809 (rank : 207)	NC score	0.009416 (rank : 208)
Query Neighborhood Hits	210	Target Neighborhood Hits	92	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WY91, Q53NU7, Q6GRN0, Q6IPJ3, Q9NW26, Q9Y325	Gene names	THAP4
Domain Architecture
Description	THAP domain-containing protein 4.

TPA_HUMAN
θ value	8.99809 (rank : 208)	NC score	-0.001487 (rank : 223)
Query Neighborhood Hits	210	Target Neighborhood Hits	324	Shared Neighborhood Hits	2
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

TTC16_MOUSE
θ value	8.99809 (rank : 209)	NC score	0.013992 (rank : 197)
Query Neighborhood Hits	210	Target Neighborhood Hits	98	Shared Neighborhood Hits	9
SwissProt Accessions	Q8C1F5	Gene names	Ttc16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

ZN471_HUMAN
θ value	8.99809 (rank : 210)	NC score	-0.005752 (rank : 228)
Query Neighborhood Hits	210	Target Neighborhood Hits	771	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BX82, O75260, Q8N3V1, Q9P2F1	Gene names	ZNF471, ERP1, KIAA1396
Domain Architecture
Description	Zinc finger protein 471 (EZFIT-related protein 1).

BLM_HUMAN
θ value	θ > 10 (rank : 211)	NC score	0.192300 (rank : 89)
Query Neighborhood Hits	210	Target Neighborhood Hits	148	Shared Neighborhood Hits	73
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

BLM_MOUSE
θ value	θ > 10 (rank : 212)	NC score	0.196403 (rank : 87)
Query Neighborhood Hits	210	Target Neighborhood Hits	108	Shared Neighborhood Hits	65
SwissProt Accessions	O88700, O88198	Gene names	Blm
Domain Architecture
Description	Bloom syndrome protein homolog (EC 3.6.1.-) (mBLM).

CC026_HUMAN
θ value	θ > 10 (rank : 213)	NC score	0.071923 (rank : 95)
Query Neighborhood Hits	210	Target Neighborhood Hits	39	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BQ75	Gene names	C3orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26.

CC026_MOUSE
θ value	θ > 10 (rank : 214)	NC score	0.052541 (rank : 113)
Query Neighborhood Hits	210	Target Neighborhood Hits	38	Shared Neighborhood Hits	23
SwissProt Accessions	Q9CZT6, Q9CY77	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26 homolog.

CHD1_HUMAN
θ value	θ > 10 (rank : 215)	NC score	0.051639 (rank : 116)
Query Neighborhood Hits	210	Target Neighborhood Hits	337	Shared Neighborhood Hits	55
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD1_MOUSE
θ value	θ > 10 (rank : 216)	NC score	0.050735 (rank : 117)
Query Neighborhood Hits	210	Target Neighborhood Hits	266	Shared Neighborhood Hits	48
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD4_HUMAN
θ value	θ > 10 (rank : 217)	NC score	0.055784 (rank : 109)
Query Neighborhood Hits	210	Target Neighborhood Hits	365	Shared Neighborhood Hits	42
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD4_MOUSE
θ value	θ > 10 (rank : 218)	NC score	0.055127 (rank : 111)
Query Neighborhood Hits	210	Target Neighborhood Hits	408	Shared Neighborhood Hits	40
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

DDX54_HUMAN
θ value	θ > 10 (rank : 219)	NC score	0.386257 (rank : 76)
Query Neighborhood Hits	210	Target Neighborhood Hits	170	Shared Neighborhood Hits	85
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).

DDX54_MOUSE
θ value	θ > 10 (rank : 220)	NC score	0.387014 (rank : 75)
Query Neighborhood Hits	210	Target Neighborhood Hits	124	Shared Neighborhood Hits	83
SwissProt Accessions	Q8K4L0	Gene names	Ddx54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54).

DDX56_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.376875 (rank : 77)
Query Neighborhood Hits	210	Target Neighborhood Hits	77	Shared Neighborhood Hits	69
SwissProt Accessions	Q9NY93, Q9H9I8	Gene names	DDX56, DDX21, NOH61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD-box protein 21).

DDX56_MOUSE
θ value	θ > 10 (rank : 222)	NC score	0.376573 (rank : 78)
Query Neighborhood Hits	210	Target Neighborhood Hits	87	Shared Neighborhood Hits	70
SwissProt Accessions	Q9D0R4	Gene names	Ddx56, D11Ertd619e, Noh61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase).

RECQ1_HUMAN
θ value	θ > 10 (rank : 223)	NC score	0.185596 (rank : 90)
Query Neighborhood Hits	210	Target Neighborhood Hits	100	Shared Neighborhood Hits	72
SwissProt Accessions	P46063	Gene names	RECQL, RECQL1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

RECQ1_MOUSE
θ value	θ > 10 (rank : 224)	NC score	0.182841 (rank : 91)
Query Neighborhood Hits	210	Target Neighborhood Hits	95	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Z129, Q9Z128	Gene names	Recql, Recql1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

RECQ4_MOUSE
θ value	θ > 10 (rank : 225)	NC score	0.238917 (rank : 81)
Query Neighborhood Hits	210	Target Neighborhood Hits	206	Shared Neighborhood Hits	78
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

SMAL1_HUMAN
θ value	θ > 10 (rank : 226)	NC score	0.065298 (rank : 100)
Query Neighborhood Hits	210	Target Neighborhood Hits	174	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

SMAL1_MOUSE
θ value	θ > 10 (rank : 227)	NC score	0.054645 (rank : 112)
Query Neighborhood Hits	210	Target Neighborhood Hits	157	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

SMCA1_MOUSE
θ value	θ > 10 (rank : 228)	NC score	0.061187 (rank : 103)
Query Neighborhood Hits	210	Target Neighborhood Hits	117	Shared Neighborhood Hits	35
SwissProt Accessions	Q6PGB8, Q8BSS1, Q91Y58	Gene names	Smarca1, Snf2l
Domain Architecture	No domain graphic available
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1) (DNA-dependent ATPase SNF2L).

Hits sorted by NC score

FANCM_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	210	Target Neighborhood Hits	210	Shared Neighborhood Hits	210
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

FANCM_MOUSE
NC score	0.964189 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	210	Target Neighborhood Hits	177	Shared Neighborhood Hits	94
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

LGP2_HUMAN
NC score	0.549746 (rank : 3)	θ value	4.16044e-13 (rank : 6)
Query Neighborhood Hits	210	Target Neighborhood Hits	94	Shared Neighborhood Hits	71
SwissProt Accessions	Q96C10, Q9HAM6	Gene names	LGP2, D11LGP2E
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2 homolog).

DDX58_MOUSE
NC score	0.549683 (rank : 4)	θ value	3.40345e-15 (rank : 4)
Query Neighborhood Hits	210	Target Neighborhood Hits	99	Shared Neighborhood Hits	62
SwissProt Accessions	Q6Q899, Q8C320, Q8C5I3, Q8C7T2	Gene names	Ddx58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

IFIH1_MOUSE
NC score	0.546745 (rank : 5)	θ value	2.43908e-13 (rank : 5)
Query Neighborhood Hits	210	Target Neighborhood Hits	126	Shared Neighborhood Hits	79
SwissProt Accessions	Q8R5F7, Q3U6S2, Q68EM4, Q8BYC9, Q8BZ01, Q8K5C7, Q8R144, Q8VE79, Q99KS4, Q9D2Z5	Gene names	Ifih1
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5).

LGP2_MOUSE
NC score	0.544115 (rank : 6)	θ value	1.74796e-11 (rank : 8)
Query Neighborhood Hits	210	Target Neighborhood Hits	86	Shared Neighborhood Hits	68
SwissProt Accessions	Q99J87, Q9D1X4	Gene names	Lgp2, D11lgp2e
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2).

DDX58_HUMAN
NC score	0.539320 (rank : 7)	θ value	1.02238e-19 (rank : 3)
Query Neighborhood Hits	210	Target Neighborhood Hits	105	Shared Neighborhood Hits	60
SwissProt Accessions	O95786, Q5HYE1, Q5VYT1, Q9NT04	Gene names	DDX58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

IFIH1_HUMAN
NC score	0.538633 (rank : 8)	θ value	4.59992e-12 (rank : 7)
Query Neighborhood Hits	210	Target Neighborhood Hits	96	Shared Neighborhood Hits	74
SwissProt Accessions	Q9BYX4, Q6DC96, Q86X56, Q96MX8, Q9H3G6	Gene names	IFIH1, MDA5, RH116
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon-induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5) (RNA helicase-DEAD box protein 116) (Murabutide-down- regulated protein).

DICER_HUMAN
NC score	0.496466 (rank : 9)	θ value	1.133e-10 (rank : 9)
Query Neighborhood Hits	210	Target Neighborhood Hits	126	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UPY3, O95943, Q9UQ02	Gene names	DICER1, DICER, HERNA, KIAA0928
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Helicase with RNase motif) (Helicase-MOI).

DICER_MOUSE
NC score	0.494386 (rank : 10)	θ value	1.9326e-10 (rank : 10)
Query Neighborhood Hits	210	Target Neighborhood Hits	140	Shared Neighborhood Hits	81
SwissProt Accessions	Q8R418	Gene names	Dicer1, Dicer, Mdcr
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Double-strand-specific ribonuclease mDCR-1).

DDX21_HUMAN
NC score	0.462561 (rank : 11)	θ value	5.81887e-07 (rank : 13)
Query Neighborhood Hits	210	Target Neighborhood Hits	308	Shared Neighborhood Hits	95
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX50_HUMAN
NC score	0.460298 (rank : 12)	θ value	8.40245e-06 (rank : 19)
Query Neighborhood Hits	210	Target Neighborhood Hits	132	Shared Neighborhood Hits	81
SwissProt Accessions	Q9BQ39, Q8WV76, Q9BWI8	Gene names	DDX50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX50_MOUSE
NC score	0.458929 (rank : 13)	θ value	1.09739e-05 (rank : 20)
Query Neighborhood Hits	210	Target Neighborhood Hits	137	Shared Neighborhood Hits	81
SwissProt Accessions	Q99MJ9	Gene names	Ddx50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX27_HUMAN
NC score	0.458660 (rank : 14)	θ value	3.41135e-07 (rank : 12)
Query Neighborhood Hits	210	Target Neighborhood Hits	197	Shared Neighborhood Hits	87
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX27_MOUSE
NC score	0.457681 (rank : 15)	θ value	5.81887e-07 (rank : 14)
Query Neighborhood Hits	210	Target Neighborhood Hits	174	Shared Neighborhood Hits	86
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX21_MOUSE
NC score	0.456697 (rank : 16)	θ value	1.69304e-06 (rank : 15)
Query Neighborhood Hits	210	Target Neighborhood Hits	350	Shared Neighborhood Hits	92
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX48_HUMAN
NC score	0.452942 (rank : 17)	θ value	6.43352e-06 (rank : 17)
Query Neighborhood Hits	210	Target Neighborhood Hits	102	Shared Neighborhood Hits	80
SwissProt Accessions	P38919, Q15033, Q96A18	Gene names	DDX48, EIF4A3, KIAA0111
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Nuclear matrix protein 265) (hNMP 265) (Eukaryotic translation initiation factor 4A isoform 3).

DDX48_MOUSE
NC score	0.452928 (rank : 18)	θ value	6.43352e-06 (rank : 18)
Query Neighborhood Hits	210	Target Neighborhood Hits	102	Shared Neighborhood Hits	80
SwissProt Accessions	Q91VC3	Gene names	Ddx48
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48).

DDX51_MOUSE
NC score	0.451505 (rank : 19)	θ value	0.000602161 (rank : 38)
Query Neighborhood Hits	210	Target Neighborhood Hits	130	Shared Neighborhood Hits	80
SwissProt Accessions	Q6P9R1, Q3U7M2	Gene names	Ddx51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX51_HUMAN
NC score	0.449193 (rank : 20)	θ value	0.000158464 (rank : 31)
Query Neighborhood Hits	210	Target Neighborhood Hits	332	Shared Neighborhood Hits	88
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX4_MOUSE
NC score	0.448781 (rank : 21)	θ value	0.00035302 (rank : 36)
Query Neighborhood Hits	210	Target Neighborhood Hits	100	Shared Neighborhood Hits	82
SwissProt Accessions	Q61496, Q9D5X7	Gene names	Ddx4, Vasa
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog) (Mvh).

DDX41_MOUSE
NC score	0.447928 (rank : 22)	θ value	2.44474e-05 (rank : 21)
Query Neighborhood Hits	210	Target Neighborhood Hits	115	Shared Neighborhood Hits	85
SwissProt Accessions	Q91VN6	Gene names	Ddx41
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41).

IF4A1_HUMAN
NC score	0.447476 (rank : 23)	θ value	0.000786445 (rank : 41)
Query Neighborhood Hits	210	Target Neighborhood Hits	106	Shared Neighborhood Hits	78
SwissProt Accessions	P60842, P04765, Q5U018, Q61516	Gene names	EIF4A1, DDX2A, EIF4A
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A1_MOUSE
NC score	0.447476 (rank : 24)	θ value	0.000786445 (rank : 42)
Query Neighborhood Hits	210	Target Neighborhood Hits	106	Shared Neighborhood Hits	78
SwissProt Accessions	P60843, P04765, Q61516	Gene names	Eif4a1, Ddx2a, Eif4a
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

DDX4_HUMAN
NC score	0.447395 (rank : 25)	θ value	0.00035302 (rank : 35)
Query Neighborhood Hits	210	Target Neighborhood Hits	123	Shared Neighborhood Hits	82
SwissProt Accessions	Q9NQI0, Q86VX0, Q9NT92, Q9NYB1	Gene names	DDX4, VASA
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog).

DDX3Y_MOUSE
NC score	0.447171 (rank : 26)	θ value	4.1701e-05 (rank : 23)
Query Neighborhood Hits	210	Target Neighborhood Hits	126	Shared Neighborhood Hits	84
SwissProt Accessions	Q62095, Q9QWS9	Gene names	Ddx3y, D1Pas1-rs1, Dead2
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal) (DEAD-box RNA helicase DEAD2) (mDEAD2) (D1Pas1-related sequence 1).

DDX41_HUMAN
NC score	0.447021 (rank : 27)	θ value	5.44631e-05 (rank : 24)
Query Neighborhood Hits	210	Target Neighborhood Hits	111	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UJV9, Q96BK6, Q96K05, Q9NT96, Q9NW04	Gene names	DDX41, ABS
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41) (DEAD box protein abstrakt homolog).

DDX52_MOUSE
NC score	0.446561 (rank : 28)	θ value	0.000461057 (rank : 37)
Query Neighborhood Hits	210	Target Neighborhood Hits	101	Shared Neighborhood Hits	81
SwissProt Accessions	Q8K301, Q8BV29	Gene names	Ddx52, Rok1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX3X_MOUSE
NC score	0.446110 (rank : 29)	θ value	9.29e-05 (rank : 28)
Query Neighborhood Hits	210	Target Neighborhood Hits	117	Shared Neighborhood Hits	84
SwissProt Accessions	Q62167, O09060, O09143	Gene names	Ddx3x, D1Pas1-rs2, Ddx3, Dead3, Erh
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (DEAD box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1Pas1-related sequence 2).

DDX3X_HUMAN
NC score	0.446066 (rank : 30)	θ value	9.29e-05 (rank : 27)
Query Neighborhood Hits	210	Target Neighborhood Hits	122	Shared Neighborhood Hits	84
SwissProt Accessions	O00571, O15536	Gene names	DDX3X, DBX, DDX3
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (Helicase-like protein 2) (HLP2) (DEAD box, X isoform).

DDX52_HUMAN
NC score	0.445780 (rank : 31)	θ value	0.000786445 (rank : 40)
Query Neighborhood Hits	210	Target Neighborhood Hits	107	Shared Neighborhood Hits	83
SwissProt Accessions	Q9Y2R4, Q86YG1, Q8N213, Q9NVE0, Q9Y482	Gene names	DDX52, ROK1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

IF4A2_HUMAN
NC score	0.445740 (rank : 32)	θ value	0.000786445 (rank : 43)
Query Neighborhood Hits	210	Target Neighborhood Hits	102	Shared Neighborhood Hits	78
SwissProt Accessions	Q14240, Q96B90, Q96EA8	Gene names	EIF4A2, DDX2B
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A2_MOUSE
NC score	0.445740 (rank : 33)	θ value	0.000786445 (rank : 44)
Query Neighborhood Hits	210	Target Neighborhood Hits	102	Shared Neighborhood Hits	78
SwissProt Accessions	P10630, Q61513, Q61514	Gene names	Eif4a2, Ddx2b
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

PL10_MOUSE
NC score	0.444897 (rank : 34)	θ value	9.29e-05 (rank : 29)
Query Neighborhood Hits	210	Target Neighborhood Hits	120	Shared Neighborhood Hits	84
SwissProt Accessions	P16381	Gene names	D1Pas1, Pl10
Domain Architecture
Description	Putative ATP-dependent RNA helicase Pl10 (EC 3.6.1.-).

DDX3Y_HUMAN
NC score	0.444863 (rank : 35)	θ value	0.000121331 (rank : 30)
Query Neighborhood Hits	210	Target Neighborhood Hits	121	Shared Neighborhood Hits	84
SwissProt Accessions	O15523, Q8IYV7	Gene names	DDX3Y, DBY
Domain Architecture
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal).

DDX49_MOUSE
NC score	0.441981 (rank : 36)	θ value	5.44631e-05 (rank : 25)
Query Neighborhood Hits	210	Target Neighborhood Hits	119	Shared Neighborhood Hits	84
SwissProt Accessions	Q4FZF3	Gene names	Ddx49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX49_HUMAN
NC score	0.440888 (rank : 37)	θ value	0.00035302 (rank : 34)
Query Neighborhood Hits	210	Target Neighborhood Hits	223	Shared Neighborhood Hits	89
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX18_MOUSE
NC score	0.439148 (rank : 38)	θ value	7.1131e-05 (rank : 26)
Query Neighborhood Hits	210	Target Neighborhood Hits	115	Shared Neighborhood Hits	75
SwissProt Accessions	Q8K363, Q3MIB0, Q8BVZ2, Q9D2E0	Gene names	Ddx18
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18).

DDX18_HUMAN
NC score	0.436658 (rank : 39)	θ value	3.19293e-05 (rank : 22)
Query Neighborhood Hits	210	Target Neighborhood Hits	124	Shared Neighborhood Hits	76
SwissProt Accessions	Q9NVP1, Q6IAU4, Q92732, Q9BQB7	Gene names	DDX18
Domain Architecture
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb).

DDX47_HUMAN
NC score	0.435722 (rank : 40)	θ value	0.00869519 (rank : 64)
Query Neighborhood Hits	210	Target Neighborhood Hits	97	Shared Neighborhood Hits	80
SwissProt Accessions	Q9H0S4, Q96GM0, Q96NV8	Gene names	DDX47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX47_MOUSE
NC score	0.435545 (rank : 41)	θ value	0.00869519 (rank : 65)
Query Neighborhood Hits	210	Target Neighborhood Hits	97	Shared Neighborhood Hits	80
SwissProt Accessions	Q9CWX9	Gene names	Ddx47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX17_MOUSE
NC score	0.434293 (rank : 42)	θ value	0.00298849 (rank : 52)
Query Neighborhood Hits	210	Target Neighborhood Hits	105	Shared Neighborhood Hits	78
SwissProt Accessions	Q501J6, Q6P5G1, Q8BIN2	Gene names	Ddx17
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17).

DDX17_HUMAN
NC score	0.434223 (rank : 43)	θ value	0.00298849 (rank : 51)
Query Neighborhood Hits	210	Target Neighborhood Hits	104	Shared Neighborhood Hits	78
SwissProt Accessions	Q92841, Q69YT1, Q6ICD6	Gene names	DDX17
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17) (RNA-dependent helicase p72) (DEAD box protein p72).

DDX43_HUMAN
NC score	0.432082 (rank : 44)	θ value	0.00298849 (rank : 53)
Query Neighborhood Hits	210	Target Neighborhood Hits	120	Shared Neighborhood Hits	80
SwissProt Accessions	Q9NXZ2, Q6NXR1	Gene names	DDX43, HAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.1.-) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen).

DDX31_HUMAN
NC score	0.431342 (rank : 45)	θ value	0.000786445 (rank : 39)
Query Neighborhood Hits	210	Target Neighborhood Hits	132	Shared Neighborhood Hits	83
SwissProt Accessions	Q9H8H2, Q5K6N2, Q5K6N3, Q5K6N4, Q5VZJ4, Q5VZJ9, Q96E91, Q96NY2, Q96SX5, Q9H5K6	Gene names	DDX31
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX31 (EC 3.6.1.-) (DEAD box protein 31) (Helicain).

DDX5_HUMAN
NC score	0.430154 (rank : 46)	θ value	0.00665767 (rank : 60)
Query Neighborhood Hits	210	Target Neighborhood Hits	102	Shared Neighborhood Hits	78
SwissProt Accessions	P17844, O75681	Gene names	DDX5, HELR, HLR1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68).

DDX5_MOUSE
NC score	0.430082 (rank : 47)	θ value	0.00665767 (rank : 61)
Query Neighborhood Hits	210	Target Neighborhood Hits	101	Shared Neighborhood Hits	78
SwissProt Accessions	Q61656	Gene names	Ddx5, Tnz2
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68) (DEAD box RNA helicase DEAD1) (mDEAD1).

DDX25_MOUSE
NC score	0.429950 (rank : 48)	θ value	0.00390308 (rank : 55)
Query Neighborhood Hits	210	Target Neighborhood Hits	98	Shared Neighborhood Hits	82
SwissProt Accessions	Q9QY15, Q8R1B6	Gene names	Ddx25, Grth
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX25_HUMAN
NC score	0.428805 (rank : 49)	θ value	0.00390308 (rank : 54)
Query Neighborhood Hits	210	Target Neighborhood Hits	93	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UHL0, Q86W81, Q8IYP1	Gene names	DDX25, GRTH
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX39_HUMAN
NC score	0.428185 (rank : 50)	θ value	0.00134147 (rank : 47)
Query Neighborhood Hits	210	Target Neighborhood Hits	94	Shared Neighborhood Hits	78
SwissProt Accessions	O00148, Q9BVP6, Q9H5W0	Gene names	DDX39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39) (Nuclear RNA helicase URH49).

DDX46_HUMAN
NC score	0.427712 (rank : 51)	θ value	0.0148317 (rank : 67)
Query Neighborhood Hits	210	Target Neighborhood Hits	357	Shared Neighborhood Hits	96
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

DDX39_MOUSE
NC score	0.427558 (rank : 52)	θ value	0.00102713 (rank : 46)
Query Neighborhood Hits	210	Target Neighborhood Hits	97	Shared Neighborhood Hits	77
SwissProt Accessions	Q8VDW0, Q3UJV4, Q8C2C2	Gene names	Ddx39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39).

DDX6_HUMAN
NC score	0.427140 (rank : 53)	θ value	0.00665767 (rank : 62)
Query Neighborhood Hits	210	Target Neighborhood Hits	97	Shared Neighborhood Hits	80
SwissProt Accessions	P26196	Gene names	DDX6, HLR2, RCK
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK).

DDX6_MOUSE
NC score	0.426804 (rank : 54)	θ value	0.00665767 (rank : 63)
Query Neighborhood Hits	210	Target Neighborhood Hits	98	Shared Neighborhood Hits	80
SwissProt Accessions	P54823	Gene names	Ddx6, Hlr2, Rck
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK homolog).

DDX46_MOUSE
NC score	0.426465 (rank : 55)	θ value	0.0148317 (rank : 68)
Query Neighborhood Hits	210	Target Neighborhood Hits	358	Shared Neighborhood Hits	95
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

DDX55_MOUSE
NC score	0.425741 (rank : 56)	θ value	0.0113563 (rank : 66)
Query Neighborhood Hits	210	Target Neighborhood Hits	111	Shared Neighborhood Hits	79
SwissProt Accessions	Q6ZPL9, Q149H5, Q3U460, Q8BZR1	Gene names	Ddx55, Kiaa1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX10_MOUSE
NC score	0.425148 (rank : 57)	θ value	0.000270298 (rank : 33)
Query Neighborhood Hits	210	Target Neighborhood Hits	233	Shared Neighborhood Hits	82
SwissProt Accessions	Q80Y44	Gene names	Ddx10
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX10_HUMAN
NC score	0.423928 (rank : 58)	θ value	0.00102713 (rank : 45)
Query Neighborhood Hits	210	Target Neighborhood Hits	210	Shared Neighborhood Hits	84
SwissProt Accessions	Q13206, Q5BJD8	Gene names	DDX10
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX23_HUMAN
NC score	0.423660 (rank : 59)	θ value	0.00509761 (rank : 57)
Query Neighborhood Hits	210	Target Neighborhood Hits	486	Shared Neighborhood Hits	101
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

DD19A_MOUSE
NC score	0.421860 (rank : 60)	θ value	0.00298849 (rank : 49)
Query Neighborhood Hits	210	Target Neighborhood Hits	105	Shared Neighborhood Hits	83
SwissProt Accessions	Q61655, Q921R0	Gene names	Ddx19a, Ddx19, Eif4a-rs1
Domain Architecture
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DEAD box RNA helicase DEAD5) (mDEAD5) (Eukaryotic translation initiation factor 4A-related sequence 1).

DDX55_HUMAN
NC score	0.421830 (rank : 61)	θ value	0.125558 (rank : 85)
Query Neighborhood Hits	210	Target Neighborhood Hits	122	Shared Neighborhood Hits	78
SwissProt Accessions	Q8NHQ9, Q658L6, Q9HCH7	Gene names	DDX55, KIAA1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DD19A_HUMAN
NC score	0.421541 (rank : 62)	θ value	0.00298849 (rank : 48)
Query Neighborhood Hits	210	Target Neighborhood Hits	107	Shared Neighborhood Hits	83
SwissProt Accessions	Q9NUU7, Q53FM0	Gene names	DDX19A, DDX19L
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DDX19-like protein).

DD19B_HUMAN
NC score	0.421461 (rank : 63)	θ value	0.00298849 (rank : 50)
Query Neighborhood Hits	210	Target Neighborhood Hits	109	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UMR2, Q6FIB7, Q6IAE0	Gene names	DDX19B, DBP5, DDX19
Domain Architecture
Description	ATP-dependent RNA helicase DDX19B (EC 3.6.1.-) (DEAD box protein 19B) (DEAD box RNA helicase DEAD5).

UAP56_HUMAN
NC score	0.421333 (rank : 64)	θ value	0.00509761 (rank : 58)
Query Neighborhood Hits	210	Target Neighborhood Hits	96	Shared Neighborhood Hits	76
SwissProt Accessions	Q13838, O43496, Q5RJ64, Q5RJ66, Q5ST94, Q5STB4, Q5STB5, Q5STB7, Q5STU4, Q5STU5, Q5STU6, Q5STU8, Q71V76	Gene names	BAT1, UAP56
Domain Architecture
Description	Spliceosome RNA helicase BAT1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (HLA-B-associated transcript-1).

UAP56_MOUSE
NC score	0.421296 (rank : 65)	θ value	0.00509761 (rank : 59)
Query Neighborhood Hits	210	Target Neighborhood Hits	96	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Z1N5, Q8HW97	Gene names	Bat1, Bat1a, Uap56
Domain Architecture	No domain graphic available
Description	Spliceosome RNA helicase Bat1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (HLA-B-associated transcript 1).

DDX28_MOUSE
NC score	0.417300 (rank : 66)	θ value	0.0431538 (rank : 73)
Query Neighborhood Hits	210	Target Neighborhood Hits	112	Shared Neighborhood Hits	84
SwissProt Accessions	Q9CWT6, Q3TQM0	Gene names	Ddx28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX53_HUMAN
NC score	0.414484 (rank : 67)	θ value	0.163984 (rank : 90)
Query Neighborhood Hits	210	Target Neighborhood Hits	124	Shared Neighborhood Hits	76
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

DDX20_MOUSE
NC score	0.410098 (rank : 68)	θ value	0.0330416 (rank : 70)
Query Neighborhood Hits	210	Target Neighborhood Hits	177	Shared Neighborhood Hits	80
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

DDX20_HUMAN
NC score	0.410048 (rank : 69)	θ value	0.0252991 (rank : 69)
Query Neighborhood Hits	210	Target Neighborhood Hits	121	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UHI6, Q96F72, Q9NVM3, Q9UF59, Q9UIY0, Q9Y659	Gene names	DDX20, DP103, GEMIN3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3).

DDX24_MOUSE
NC score	0.409796 (rank : 70)	θ value	0.0330416 (rank : 71)
Query Neighborhood Hits	210	Target Neighborhood Hits	147	Shared Neighborhood Hits	80
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX24_HUMAN
NC score	0.407673 (rank : 71)	θ value	0.0563607 (rank : 78)
Query Neighborhood Hits	210	Target Neighborhood Hits	190	Shared Neighborhood Hits	83
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX1_MOUSE
NC score	0.400314 (rank : 72)	θ value	0.0736092 (rank : 81)
Query Neighborhood Hits	210	Target Neighborhood Hits	112	Shared Neighborhood Hits	75
SwissProt Accessions	Q91VR5, Q3TU41	Gene names	Ddx1
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1).

DDX1_HUMAN
NC score	0.399812 (rank : 73)	θ value	0.0736092 (rank : 80)
Query Neighborhood Hits	210	Target Neighborhood Hits	110	Shared Neighborhood Hits	74
SwissProt Accessions	Q92499	Gene names	DDX1
Domain Architecture
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB).

DDX28_HUMAN
NC score	0.388659 (rank : 74)	θ value	6.88961 (rank : 186)
Query Neighborhood Hits	210	Target Neighborhood Hits	103	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NUL7	Gene names	DDX28, MDDX28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX54_MOUSE
NC score	0.387014 (rank : 75)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	210	Target Neighborhood Hits	124	Shared Neighborhood Hits	83
SwissProt Accessions	Q8K4L0	Gene names	Ddx54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54).

DDX54_HUMAN
NC score	0.386257 (rank : 76)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	210	Target Neighborhood Hits	170	Shared Neighborhood Hits	85
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).

DDX56_HUMAN
NC score	0.376875 (rank : 77)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	210	Target Neighborhood Hits	77	Shared Neighborhood Hits	69
SwissProt Accessions	Q9NY93, Q9H9I8	Gene names	DDX56, DDX21, NOH61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD-box protein 21).

DDX56_MOUSE
NC score	0.376573 (rank : 78)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	210	Target Neighborhood Hits	87	Shared Neighborhood Hits	70
SwissProt Accessions	Q9D0R4	Gene names	Ddx56, D11Ertd619e, Noh61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase).

RECQ4_HUMAN
NC score	0.278510 (rank : 79)	θ value	0.163984 (rank : 92)
Query Neighborhood Hits	210	Target Neighborhood Hits	177	Shared Neighborhood Hits	80
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

ERCC4_HUMAN
NC score	0.274711 (rank : 80)	θ value	4.76016e-09 (rank : 11)
Query Neighborhood Hits	210	Target Neighborhood Hits	32	Shared Neighborhood Hits	8
SwissProt Accessions	Q92889, O00140, Q8TD83	Gene names	ERCC4, ERCC11, XPF
Domain Architecture
Description	DNA repair endonuclease XPF (EC 3.1.-.-) (DNA excision repair protein ERCC-4) (DNA-repair protein complementing XP-F cells) (Xeroderma pigmentosum group F-complementing protein).

RECQ4_MOUSE
NC score	0.238917 (rank : 81)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	210	Target Neighborhood Hits	206	Shared Neighborhood Hits	78
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

ERCC4_MOUSE
NC score	0.235667 (rank : 82)	θ value	1.69304e-06 (rank : 16)
Query Neighborhood Hits	210	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QZD4, O54810, Q8R0I3	Gene names	Ercc4
Domain Architecture
Description	DNA repair endonuclease XPF (EC 3.1.-.-) (DNA excision repair protein ERCC-4).

HELC1_HUMAN
NC score	0.227583 (rank : 83)	θ value	0.000158464 (rank : 32)
Query Neighborhood Hits	210	Target Neighborhood Hits	71	Shared Neighborhood Hits	39
SwissProt Accessions	Q8N3C0, O43738, Q9H1I9, Q9NTR0	Gene names	ASCC3, HELIC1
Domain Architecture	No domain graphic available
Description	Activating signal cointegrator 1 complex subunit 3 (EC 3.6.1.-) (ASC-1 complex subunit p200) (Trip4 complex subunit p200) (Helicase, ATP binding 1).

RECQ5_HUMAN
NC score	0.223772 (rank : 84)	θ value	0.813845 (rank : 117)
Query Neighborhood Hits	210	Target Neighborhood Hits	390	Shared Neighborhood Hits	74
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

WRN_HUMAN
NC score	0.208797 (rank : 85)	θ value	1.81305 (rank : 137)
Query Neighborhood Hits	210	Target Neighborhood Hits	132	Shared Neighborhood Hits	79
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

WRN_MOUSE
NC score	0.202054 (rank : 86)	θ value	6.88961 (rank : 193)
Query Neighborhood Hits	210	Target Neighborhood Hits	295	Shared Neighborhood Hits	87
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

BLM_MOUSE
NC score	0.196403 (rank : 87)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	210	Target Neighborhood Hits	108	Shared Neighborhood Hits	65
SwissProt Accessions	O88700, O88198	Gene names	Blm
Domain Architecture
Description	Bloom syndrome protein homolog (EC 3.6.1.-) (mBLM).

U520_HUMAN
NC score	0.194200 (rank : 88)	θ value	0.0431538 (rank : 74)
Query Neighborhood Hits	210	Target Neighborhood Hits	88	Shared Neighborhood Hits	42
SwissProt Accessions	O75643, O94884, Q6PX59, Q96IF2, Q9H7S0	Gene names	ASCC3L1, HELIC2, KIAA0788
Domain Architecture	No domain graphic available
Description	U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.1.-) (U5 snRNP-specific 200 kDa protein) (U5-200KD) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog).

BLM_HUMAN
NC score	0.192300 (rank : 89)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	210	Target Neighborhood Hits	148	Shared Neighborhood Hits	73
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

RECQ1_HUMAN
NC score	0.185596 (rank : 90)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	210	Target Neighborhood Hits	100	Shared Neighborhood Hits	72
SwissProt Accessions	P46063	Gene names	RECQL, RECQL1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

RECQ1_MOUSE
NC score	0.182841 (rank : 91)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	210	Target Neighborhood Hits	95	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Z129, Q9Z128	Gene names	Recql, Recql1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

ATRX_HUMAN
NC score	0.078195 (rank : 92)	θ value	0.47712 (rank : 99)
Query Neighborhood Hits	210	Target Neighborhood Hits	842	Shared Neighborhood Hits	68
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

CHD5_HUMAN
NC score	0.076317 (rank : 93)	θ value	0.0563607 (rank : 76)
Query Neighborhood Hits	210	Target Neighborhood Hits	349	Shared Neighborhood Hits	40
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

BTAF1_HUMAN
NC score	0.072691 (rank : 94)	θ value	0.125558 (rank : 84)
Query Neighborhood Hits	210	Target Neighborhood Hits	97	Shared Neighborhood Hits	19
SwissProt Accessions	O14981, O43578	Gene names	BTAF1, TAF172
Domain Architecture
Description	TATA-binding protein-associated factor 172 (EC 3.6.1.-) (ATP-dependent helicase BTAF1) (TBP-associated factor 172) (TAF-172) (TAF(II)170) (B- TFIID transcription factor-associated 170 kDa subunit).

CC026_HUMAN
NC score	0.071923 (rank : 95)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	210	Target Neighborhood Hits	39	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BQ75	Gene names	C3orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26.

ATRX_MOUSE
NC score	0.071435 (rank : 96)	θ value	0.62314 (rank : 103)
Query Neighborhood Hits	210	Target Neighborhood Hits	682	Shared Neighborhood Hits	55
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

AQR_MOUSE
NC score	0.069223 (rank : 97)	θ value	0.365318 (rank : 97)
Query Neighborhood Hits	210	Target Neighborhood Hits	62	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CFQ3, P97871, Q3U9N1, Q3ULE8, Q80TX8	Gene names	Aqr, Kiaa0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius.

CHD3_HUMAN
NC score	0.069208 (rank : 98)	θ value	4.03905 (rank : 161)
Query Neighborhood Hits	210	Target Neighborhood Hits	397	Shared Neighborhood Hits	42
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

AQR_HUMAN
NC score	0.067107 (rank : 99)	θ value	0.365318 (rank : 96)
Query Neighborhood Hits	210	Target Neighborhood Hits	88	Shared Neighborhood Hits	7
SwissProt Accessions	O60306, Q2YDX9, Q6IRU8, Q6PIC8	Gene names	AQR, KIAA0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius (Intron-binding protein of 160 kDa) (IBP160).

SMAL1_HUMAN
NC score	0.065298 (rank : 100)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	210	Target Neighborhood Hits	174	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

CTR9_MOUSE
NC score	0.063350 (rank : 101)	θ value	0.0563607 (rank : 77)
Query Neighborhood Hits	210	Target Neighborhood Hits	427	Shared Neighborhood Hits	25
SwissProt Accessions	Q62018, Q3UFF5, Q3UY40, Q66JX4, Q7TPS6, Q8BND9, Q8BRD1, Q8C9W7, Q8C9Y3, Q8CHI1	Gene names	Ctr9, Kiaa0155, Sh2bp1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) (Tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa) (TPR-containing, SH2-binding phosphoprotein of 150 kDa) (p150TSP).

CLSPN_HUMAN
NC score	0.061797 (rank : 102)	θ value	0.163984 (rank : 88)
Query Neighborhood Hits	210	Target Neighborhood Hits	433	Shared Neighborhood Hits	33
SwissProt Accessions	Q9HAW4, Q5VYG0, Q6P6H5, Q8IWI1	Gene names	CLSPN
Domain Architecture	No domain graphic available
Description	Claspin (hClaspin) (Hu-Claspin).

SMCA1_MOUSE
NC score	0.061187 (rank : 103)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	210	Target Neighborhood Hits	117	Shared Neighborhood Hits	35
SwissProt Accessions	Q6PGB8, Q8BSS1, Q91Y58	Gene names	Smarca1, Snf2l
Domain Architecture	No domain graphic available
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1) (DNA-dependent ATPase SNF2L).

RAD54_MOUSE
NC score	0.060946 (rank : 104)	θ value	0.62314 (rank : 108)
Query Neighborhood Hits	210	Target Neighborhood Hits	51	Shared Neighborhood Hits	17
SwissProt Accessions	P70270, Q8BSR5, Q8C2C4, Q8K3D4	Gene names	Rad54l, Rad54
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (mRAD54) (mHR54).

RAD54_HUMAN
NC score	0.059984 (rank : 105)	θ value	0.813845 (rank : 116)
Query Neighborhood Hits	210	Target Neighborhood Hits	51	Shared Neighborhood Hits	16
SwissProt Accessions	Q92698, Q6IUY3	Gene names	RAD54L, RAD54A
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (hRAD54) (hHR54).

SMCA1_HUMAN
NC score	0.059842 (rank : 106)	θ value	0.0330416 (rank : 72)
Query Neighborhood Hits	210	Target Neighborhood Hits	105	Shared Neighborhood Hits	27
SwissProt Accessions	P28370, Q5JV41, Q5JV42	Gene names	SMARCA1, SNF2L, SNF2L1
Domain Architecture
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1).

CTR9_HUMAN
NC score	0.058607 (rank : 107)	θ value	0.163984 (rank : 89)
Query Neighborhood Hits	210	Target Neighborhood Hits	383	Shared Neighborhood Hits	18
SwissProt Accessions	Q6PD62, Q15015	Gene names	CTR9, KIAA0155, SH2BP1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1).

NOL8_HUMAN
NC score	0.056845 (rank : 108)	θ value	0.0736092 (rank : 82)
Query Neighborhood Hits	210	Target Neighborhood Hits	297	Shared Neighborhood Hits	28
SwissProt Accessions	Q76FK4, Q5TCC7, Q5TCC8, Q5TCD3, Q5TCD5, Q5TCD6, Q5TCD7, Q76D35, Q7L3E2, Q9H586, Q9H795, Q9H7W7, Q9H9J6, Q9NWA4, Q9NWM4	Gene names	NOL8, NOP132
Domain Architecture	No domain graphic available
Description	Nucleolar protein 8 (Nucleolar protein Nop132).

CHD4_HUMAN
NC score	0.055784 (rank : 109)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	210	Target Neighborhood Hits	365	Shared Neighborhood Hits	42
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CCNB3_MOUSE
NC score	0.055271 (rank : 110)	θ value	0.00509761 (rank : 56)
Query Neighborhood Hits	210	Target Neighborhood Hits	211	Shared Neighborhood Hits	13
SwissProt Accessions	Q810T2, Q810T3, Q8VDC8	Gene names	Ccnb3, Cycb3
Domain Architecture
Description	G2/mitotic-specific cyclin-B3.

CHD4_MOUSE
NC score	0.055127 (rank : 111)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	210	Target Neighborhood Hits	408	Shared Neighborhood Hits	40
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

SMAL1_MOUSE
NC score	0.054645 (rank : 112)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	210	Target Neighborhood Hits	157	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

CC026_MOUSE
NC score	0.052541 (rank : 113)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	210	Target Neighborhood Hits	38	Shared Neighborhood Hits	23
SwissProt Accessions	Q9CZT6, Q9CY77	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26 homolog.

SMCA2_HUMAN
NC score	0.052490 (rank : 114)	θ value	1.06291 (rank : 121)
Query Neighborhood Hits	210	Target Neighborhood Hits	503	Shared Neighborhood Hits	37
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

IWS1_HUMAN
NC score	0.052316 (rank : 115)	θ value	2.36792 (rank : 143)
Query Neighborhood Hits	210	Target Neighborhood Hits	1241	Shared Neighborhood Hits	63
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

CHD1_HUMAN
NC score	0.051639 (rank : 116)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	210	Target Neighborhood Hits	337	Shared Neighborhood Hits	55
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD1_MOUSE
NC score	0.050735 (rank : 117)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	210	Target Neighborhood Hits	266	Shared Neighborhood Hits	48
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

SMCA4_HUMAN
NC score	0.049890 (rank : 118)	θ value	6.88961 (rank : 192)
Query Neighborhood Hits	210	Target Neighborhood Hits	597	Shared Neighborhood Hits	44
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

SMRCD_MOUSE
NC score	0.049260 (rank : 119)	θ value	5.27518 (rank : 181)
Query Neighborhood Hits	210	Target Neighborhood Hits	96	Shared Neighborhood Hits	24
SwissProt Accessions	Q04692	Gene names	Smarcad1, Etl1, Kiaa1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase SMARCAD1) (Enhancer trap locus homolog 1) (Etl-1).

SMRCD_HUMAN
NC score	0.049047 (rank : 120)	θ value	5.27518 (rank : 180)
Query Neighborhood Hits	210	Target Neighborhood Hits	117	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H4L7, Q96SX1, Q9H017, Q9H860, Q9NPU9, Q9ULU7	Gene names	SMARCAD1, KIAA1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase 1) (hHEL1).

CHD8_HUMAN
NC score	0.047662 (rank : 121)	θ value	1.38821 (rank : 125)
Query Neighborhood Hits	210	Target Neighborhood Hits	235	Shared Neighborhood Hits	28
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

PKCB1_HUMAN
NC score	0.047214 (rank : 122)	θ value	0.47712 (rank : 102)
Query Neighborhood Hits	210	Target Neighborhood Hits	488	Shared Neighborhood Hits	33
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

GCF_HUMAN
NC score	0.046766 (rank : 123)	θ value	0.365318 (rank : 98)
Query Neighborhood Hits	210	Target Neighborhood Hits	107	Shared Neighborhood Hits	9
SwissProt Accessions	P16383, O95032	Gene names	TCF9, C2orf3
Domain Architecture	No domain graphic available
Description	GC-rich sequence DNA-binding factor (GCF) (Transcription factor 9) (TCF-9).

IWS1_MOUSE
NC score	0.044559 (rank : 124)	θ value	1.38821 (rank : 128)
Query Neighborhood Hits	210	Target Neighborhood Hits	1258	Shared Neighborhood Hits	64
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

RXINP_MOUSE
NC score	0.043969 (rank : 125)	θ value	0.279714 (rank : 93)
Query Neighborhood Hits	210	Target Neighborhood Hits	99	Shared Neighborhood Hits	8
SwissProt Accessions	Q5U5Q9, Q60811	Gene names	Rxrip110, Rip110
Domain Architecture	No domain graphic available
Description	Retinoid X receptor-interacting protein 110.

CCNB3_HUMAN
NC score	0.043572 (rank : 126)	θ value	1.81305 (rank : 131)
Query Neighborhood Hits	210	Target Neighborhood Hits	368	Shared Neighborhood Hits	30
SwissProt Accessions	Q8WWL7, Q96SB5, Q96SB6, Q96SB7, Q9NT38	Gene names	CCNB3, CYCB3
Domain Architecture
Description	G2/mitotic-specific cyclin-B3.

MDM2_HUMAN
NC score	0.041645 (rank : 127)	θ value	0.163984 (rank : 91)
Query Neighborhood Hits	210	Target Neighborhood Hits	92	Shared Neighborhood Hits	6
SwissProt Accessions	Q00987, Q13226, Q13297, Q13298, Q13299, Q13300, Q13301, Q53XW0, Q71TW9, Q9UGI3, Q9UMT8	Gene names	MDM2
Domain Architecture
Description	Ubiquitin-protein ligase E3 Mdm2 (EC 6.3.2.-) (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein) (Hdm2).

SETX_HUMAN
NC score	0.040398 (rank : 128)	θ value	0.62314 (rank : 109)
Query Neighborhood Hits	210	Target Neighborhood Hits	368	Shared Neighborhood Hits	25
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

AF9_HUMAN
NC score	0.038688 (rank : 129)	θ value	1.38821 (rank : 123)
Query Neighborhood Hits	210	Target Neighborhood Hits	202	Shared Neighborhood Hits	16
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

CJ068_HUMAN
NC score	0.037736 (rank : 130)	θ value	2.36792 (rank : 141)
Query Neighborhood Hits	210	Target Neighborhood Hits	316	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H943, Q8N7T7	Gene names	C10orf68
Domain Architecture	No domain graphic available
Description	Protein C10orf68.

CIR_MOUSE
NC score	0.037300 (rank : 131)	θ value	1.38821 (rank : 126)
Query Neighborhood Hits	210	Target Neighborhood Hits	255	Shared Neighborhood Hits	21
SwissProt Accessions	Q9DA19, Q3V2N9, Q4KL44, Q52KL9, Q5FW66	Gene names	Cir
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor.

RPGR_MOUSE
NC score	0.037041 (rank : 132)	θ value	0.0961366 (rank : 83)
Query Neighborhood Hits	210	Target Neighborhood Hits	281	Shared Neighborhood Hits	22
SwissProt Accessions	Q9R0X5, O88408, Q9CU92	Gene names	Rpgr
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator (mRpgr).

BCAS1_MOUSE
NC score	0.036942 (rank : 133)	θ value	0.47712 (rank : 100)
Query Neighborhood Hits	210	Target Neighborhood Hits	215	Shared Neighborhood Hits	7
SwissProt Accessions	Q80YN3, Q9CVA1	Gene names	Bcas1, Nabc1
Domain Architecture	No domain graphic available
Description	Breast carcinoma amplified sequence 1 homolog (Novel amplified in breast cancer 1 homolog).

SGOL2_HUMAN
NC score	0.036469 (rank : 134)	θ value	0.813845 (rank : 118)
Query Neighborhood Hits	210	Target Neighborhood Hits	207	Shared Neighborhood Hits	16
SwissProt Accessions	Q562F6, Q53RR9, Q53T20, Q86XY4, Q8IWK2, Q8IZK1, Q8N1Q5, Q96LQ3	Gene names	SGOL2
Domain Architecture	No domain graphic available
Description	Shugoshin-like 2 (Tripin).

WDHD1_MOUSE
NC score	0.036317 (rank : 135)	θ value	0.0563607 (rank : 79)
Query Neighborhood Hits	210	Target Neighborhood Hits	414	Shared Neighborhood Hits	15
SwissProt Accessions	P59328, Q6P408	Gene names	Wdhd1, And1
Domain Architecture	No domain graphic available
Description	WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA- binding protein 1) (And-1).

DMP1_MOUSE
NC score	0.035660 (rank : 136)	θ value	4.03905 (rank : 163)
Query Neighborhood Hits	210	Target Neighborhood Hits	498	Shared Neighborhood Hits	31
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

IF2P_HUMAN
NC score	0.035585 (rank : 137)	θ value	0.813845 (rank : 114)
Query Neighborhood Hits	210	Target Neighborhood Hits	889	Shared Neighborhood Hits	46
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

NKTR_HUMAN
NC score	0.035029 (rank : 138)	θ value	0.813845 (rank : 115)
Query Neighborhood Hits	210	Target Neighborhood Hits	658	Shared Neighborhood Hits	49
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

LUC7L_MOUSE
NC score	0.034683 (rank : 139)	θ value	2.36792 (rank : 145)
Query Neighborhood Hits	210	Target Neighborhood Hits	111	Shared Neighborhood Hits	12
SwissProt Accessions	Q9CYI4, Q8K247, Q9CWM1	Gene names	Luc7l
Domain Architecture
Description	Putative RNA-binding protein Luc7-like 1.

NBR1_HUMAN
NC score	0.034555 (rank : 140)	θ value	0.47712 (rank : 101)
Query Neighborhood Hits	210	Target Neighborhood Hits	105	Shared Neighborhood Hits	5
SwissProt Accessions	Q14596, Q13173, Q15026, Q96GB6, Q9NRF7	Gene names	NBR1, 1A13B, KIAA0049, M17S2
Domain Architecture
Description	Next to BRCA1 gene 1 protein (Neighbor of BRCA1 gene 1 protein) (Membrane component, chromosome 17, surface marker 2) (1A1-3B).

LUC7L_HUMAN
NC score	0.034193 (rank : 141)	θ value	2.36792 (rank : 144)
Query Neighborhood Hits	210	Target Neighborhood Hits	130	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NQ29, Q96S32, Q9NPH4	Gene names	LUC7L, LUC7L1
Domain Architecture
Description	Putative RNA-binding protein Luc7-like 1 (SR+89) (Putative SR protein LUC7B1).

MACOI_HUMAN
NC score	0.034142 (rank : 142)	θ value	0.62314 (rank : 107)
Query Neighborhood Hits	210	Target Neighborhood Hits	650	Shared Neighborhood Hits	29
SwissProt Accessions	Q8N5G2, Q2TLX5, Q2TLX6, Q9NVG6	Gene names	TMEM57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57).

NOL7_HUMAN
NC score	0.033786 (rank : 143)	θ value	2.36792 (rank : 148)
Query Neighborhood Hits	210	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UMY1, Q5T297, Q9Y3U7	Gene names	NOL7, C6orf90, NOP27
Domain Architecture	No domain graphic available
Description	Nucleolar protein 7 (Nucleolar protein of 27 kDa).

RFC1_HUMAN
NC score	0.033432 (rank : 144)	θ value	1.81305 (rank : 136)
Query Neighborhood Hits	210	Target Neighborhood Hits	352	Shared Neighborhood Hits	23
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

NOLC1_HUMAN
NC score	0.033236 (rank : 145)	θ value	3.0926 (rank : 157)
Query Neighborhood Hits	210	Target Neighborhood Hits	452	Shared Neighborhood Hits	25
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

SK2L2_MOUSE
NC score	0.032946 (rank : 146)	θ value	8.99809 (rank : 206)
Query Neighborhood Hits	210	Target Neighborhood Hits	45	Shared Neighborhood Hits	12
SwissProt Accessions	Q9CZU3	Gene names	Skiv2l2
Domain Architecture	No domain graphic available
Description	Superkiller viralicidic activity 2-like 2 (EC 3.6.1.-) (ATP-dependent helicase SKIV2L2).

SK2L2_HUMAN
NC score	0.032784 (rank : 147)	θ value	8.99809 (rank : 205)
Query Neighborhood Hits	210	Target Neighborhood Hits	36	Shared Neighborhood Hits	12
SwissProt Accessions	P42285, Q8TAG2	Gene names	SKIV2L2, KIAA0052
Domain Architecture	No domain graphic available
Description	Superkiller viralicidic activity 2-like 2 (EC 3.6.1.-) (ATP-dependent helicase SKIV2L2).

UBP28_HUMAN
NC score	0.031102 (rank : 148)	θ value	0.62314 (rank : 112)
Query Neighborhood Hits	210	Target Neighborhood Hits	117	Shared Neighborhood Hits	6
SwissProt Accessions	Q96RU2, Q9P213	Gene names	USP28, KIAA1515
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

ANR12_HUMAN
NC score	0.031073 (rank : 149)	θ value	0.0563607 (rank : 75)
Query Neighborhood Hits	210	Target Neighborhood Hits	1081	Shared Neighborhood Hits	53
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

LC7L2_MOUSE
NC score	0.031038 (rank : 150)	θ value	5.27518 (rank : 177)
Query Neighborhood Hits	210	Target Neighborhood Hits	244	Shared Neighborhood Hits	18
SwissProt Accessions	Q7TNC4, Q99LM5, Q99PC3	Gene names	Luc7l2
Domain Architecture
Description	Putative RNA-binding protein Luc7-like 2 (CGI-74 homolog).

ZCH11_HUMAN
NC score	0.030736 (rank : 151)	θ value	4.03905 (rank : 169)
Query Neighborhood Hits	210	Target Neighborhood Hits	278	Shared Neighborhood Hits	23
SwissProt Accessions	Q5TAX3, Q12764, Q5TAX4, Q86XZ3	Gene names	ZCCHC11, KIAA0191
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 11.

SYNE2_HUMAN
NC score	0.030664 (rank : 152)	θ value	0.279714 (rank : 95)
Query Neighborhood Hits	210	Target Neighborhood Hits	1323	Shared Neighborhood Hits	52
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

DMD_HUMAN
NC score	0.030631 (rank : 153)	θ value	0.125558 (rank : 86)
Query Neighborhood Hits	210	Target Neighborhood Hits	1135	Shared Neighborhood Hits	33
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

MACOI_MOUSE
NC score	0.030604 (rank : 154)	θ value	1.81305 (rank : 134)
Query Neighborhood Hits	210	Target Neighborhood Hits	620	Shared Neighborhood Hits	26
SwissProt Accessions	Q7TQE6	Gene names	Tmem57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57) (Brain-specific adaptor protein C61).

LC7L2_HUMAN
NC score	0.030093 (rank : 155)	θ value	5.27518 (rank : 176)
Query Neighborhood Hits	210	Target Neighborhood Hits	235	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y383, Q8IUP9, Q9NVL3, Q9NVN7, Q9UQN1	Gene names	LUC7L2
Domain Architecture
Description	Putative RNA-binding protein Luc7-like 2.

DZIP3_MOUSE
NC score	0.030086 (rank : 156)	θ value	0.62314 (rank : 105)
Query Neighborhood Hits	210	Target Neighborhood Hits	414	Shared Neighborhood Hits	23
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

NUF2_MOUSE
NC score	0.029893 (rank : 157)	θ value	1.06291 (rank : 120)
Query Neighborhood Hits	210	Target Neighborhood Hits	585	Shared Neighborhood Hits	25
SwissProt Accessions	Q99P69, Q8BTK7, Q8VE05, Q9CST5	Gene names	Cdca1, Nuf2r
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (Cell division cycle-associated protein 1).

DMD_MOUSE
NC score	0.029779 (rank : 158)	θ value	0.125558 (rank : 87)
Query Neighborhood Hits	210	Target Neighborhood Hits	1111	Shared Neighborhood Hits	38
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

UBP28_MOUSE
NC score	0.029591 (rank : 159)	θ value	0.813845 (rank : 119)
Query Neighborhood Hits	210	Target Neighborhood Hits	178	Shared Neighborhood Hits	6
SwissProt Accessions	Q5I043, Q6NZP3, Q6ZPP1, Q8BWI1	Gene names	Usp28, Kiaa1515
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

DSPP_HUMAN
NC score	0.029312 (rank : 160)	θ value	4.03905 (rank : 164)
Query Neighborhood Hits	210	Target Neighborhood Hits	645	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

PHF3_HUMAN
NC score	0.029268 (rank : 161)	θ value	1.81305 (rank : 135)
Query Neighborhood Hits	210	Target Neighborhood Hits	419	Shared Neighborhood Hits	24
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

UBXD6_MOUSE
NC score	0.029037 (rank : 162)	θ value	2.36792 (rank : 150)
Query Neighborhood Hits	210	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QZ49	Gene names	Ubxd6, D0H8S2298E, Rep8
Domain Architecture	No domain graphic available
Description	UBX domain-containing protein 6 (Reproduction 8 protein) (Protein Rep- 8).

SMC4_MOUSE
NC score	0.027695 (rank : 163)	θ value	0.279714 (rank : 94)
Query Neighborhood Hits	210	Target Neighborhood Hits	830	Shared Neighborhood Hits	33
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

GOGB1_HUMAN
NC score	0.027432 (rank : 164)	θ value	0.62314 (rank : 106)
Query Neighborhood Hits	210	Target Neighborhood Hits	2297	Shared Neighborhood Hits	73
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

XRCC1_MOUSE
NC score	0.026358 (rank : 165)	θ value	1.81305 (rank : 138)
Query Neighborhood Hits	210	Target Neighborhood Hits	242	Shared Neighborhood Hits	8
SwissProt Accessions	Q60596, Q3THC5, Q5U435, Q7TNQ5	Gene names	Xrcc1, Xrcc-1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

ZFAN3_MOUSE
NC score	0.026273 (rank : 166)	θ value	2.36792 (rank : 151)
Query Neighborhood Hits	210	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q497H0, Q8K230, Q8R2V7, Q8R3V1	Gene names	Zfand3, Tex27
Domain Architecture	No domain graphic available
Description	AN1-type zinc finger protein 3 (Testis-expressed sequence 27).

GSH1_MOUSE
NC score	0.025554 (rank : 167)	θ value	1.81305 (rank : 133)
Query Neighborhood Hits	210	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	P97494, O09166, Q8VCS5	Gene names	Gclc, Glclc
Domain Architecture
Description	Glutamate--cysteine ligase catalytic subunit (EC 6.3.2.2) (Gamma- glutamylcysteine synthetase) (Gamma-ECS) (GCS heavy chain).

RAD1_MOUSE
NC score	0.024200 (rank : 168)	θ value	3.0926 (rank : 158)
Query Neighborhood Hits	210	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QWZ1, O70452, O88391, Q3TGU1, Q3UG66, Q9QWZ3	Gene names	Rad1, Rec1
Domain Architecture	No domain graphic available
Description	Cell cycle checkpoint protein RAD1 (EC 3.1.11.2) (DNA repair exonuclease rad1 homolog) (Rad1-like DNA damage checkpoint protein) (mRAD1).

DNJC1_HUMAN
NC score	0.023771 (rank : 169)	θ value	0.813845 (rank : 113)
Query Neighborhood Hits	210	Target Neighborhood Hits	127	Shared Neighborhood Hits	5
SwissProt Accessions	Q96KC8	Gene names	DNAJC1
Domain Architecture
Description	DnaJ homolog subfamily C member 1.

RRBP1_MOUSE
NC score	0.023611 (rank : 170)	θ value	8.99809 (rank : 204)
Query Neighborhood Hits	210	Target Neighborhood Hits	1650	Shared Neighborhood Hits	57
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

CENPE_HUMAN
NC score	0.022075 (rank : 171)	θ value	2.36792 (rank : 140)
Query Neighborhood Hits	210	Target Neighborhood Hits	2060	Shared Neighborhood Hits	69
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

C102B_HUMAN
NC score	0.021882 (rank : 172)	θ value	5.27518 (rank : 172)
Query Neighborhood Hits	210	Target Neighborhood Hits	542	Shared Neighborhood Hits	26
SwissProt Accessions	Q68D86, Q7Z467, Q8NDK7, Q9H5C1	Gene names	CCDC102B, C18orf14
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 102B.

SRRM2_MOUSE
NC score	0.021857 (rank : 173)	θ value	3.0926 (rank : 159)
Query Neighborhood Hits	210	Target Neighborhood Hits	1470	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

CCD39_MOUSE
NC score	0.021143 (rank : 174)	θ value	1.81305 (rank : 130)
Query Neighborhood Hits	210	Target Neighborhood Hits	1026	Shared Neighborhood Hits	36
SwissProt Accessions	Q9D5Y1, Q8CDG6	Gene names	Ccdc39, D3Ertd789e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

BAZ2A_MOUSE
NC score	0.020914 (rank : 175)	θ value	2.36792 (rank : 139)
Query Neighborhood Hits	210	Target Neighborhood Hits	744	Shared Neighborhood Hits	33
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

RBCC1_MOUSE
NC score	0.020874 (rank : 176)	θ value	4.03905 (rank : 168)
Query Neighborhood Hits	210	Target Neighborhood Hits	1048	Shared Neighborhood Hits	38
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

SFRS4_MOUSE
NC score	0.020644 (rank : 177)	θ value	0.62314 (rank : 110)
Query Neighborhood Hits	210	Target Neighborhood Hits	406	Shared Neighborhood Hits	17
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

FLIP1_HUMAN
NC score	0.020526 (rank : 178)	θ value	3.0926 (rank : 154)
Query Neighborhood Hits	210	Target Neighborhood Hits	1405	Shared Neighborhood Hits	48
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

CUTL1_MOUSE
NC score	0.019612 (rank : 179)	θ value	1.81305 (rank : 132)
Query Neighborhood Hits	210	Target Neighborhood Hits	1620	Shared Neighborhood Hits	48
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

HMMR_MOUSE
NC score	0.019388 (rank : 180)	θ value	3.0926 (rank : 156)
Query Neighborhood Hits	210	Target Neighborhood Hits	1178	Shared Neighborhood Hits	46
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

CUTL1_HUMAN
NC score	0.018952 (rank : 181)	θ value	4.03905 (rank : 162)
Query Neighborhood Hits	210	Target Neighborhood Hits	1574	Shared Neighborhood Hits	48
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

NIN_HUMAN
NC score	0.018826 (rank : 182)	θ value	4.03905 (rank : 167)
Query Neighborhood Hits	210	Target Neighborhood Hits	1416	Shared Neighborhood Hits	43
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

CCD41_MOUSE
NC score	0.018661 (rank : 183)	θ value	6.88961 (rank : 184)
Query Neighborhood Hits	210	Target Neighborhood Hits	1399	Shared Neighborhood Hits	57
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

GOGA1_HUMAN
NC score	0.017774 (rank : 184)	θ value	3.0926 (rank : 155)
Query Neighborhood Hits	210	Target Neighborhood Hits	1222	Shared Neighborhood Hits	44
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

GP137_HUMAN
NC score	0.016781 (rank : 185)	θ value	5.27518 (rank : 173)
Query Neighborhood Hits	210	Target Neighborhood Hits	119	Shared Neighborhood Hits	8
SwissProt Accessions	Q14444, Q15074	Gene names	M11S1, GPIP137
Domain Architecture	No domain graphic available
Description	GPI-anchored protein p137 (p137GPI) (Membrane component chromosome 11 surface marker 1).

RPTN_MOUSE
NC score	0.016731 (rank : 186)	θ value	8.99809 (rank : 203)
Query Neighborhood Hits	210	Target Neighborhood Hits	650	Shared Neighborhood Hits	34
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

KNTC2_MOUSE
NC score	0.016368 (rank : 187)	θ value	6.88961 (rank : 190)
Query Neighborhood Hits	210	Target Neighborhood Hits	692	Shared Neighborhood Hits	25
SwissProt Accessions	Q9D0F1, Q3TQT6, Q3UWM5, Q99P70	Gene names	Kntc2, Hec1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (Kinetochore-associated protein 2).

MYT1_HUMAN
NC score	0.016292 (rank : 188)	θ value	2.36792 (rank : 147)
Query Neighborhood Hits	210	Target Neighborhood Hits	475	Shared Neighborhood Hits	24
SwissProt Accessions	Q01538, O94922, Q9UPV2	Gene names	MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1
Domain Architecture
Description	Myelin transcription factor 1 (MyT1) (MyTI) (Proteolipid protein- binding protein) (PLPB1).

RASF5_MOUSE
NC score	0.016271 (rank : 189)	θ value	2.36792 (rank : 149)
Query Neighborhood Hits	210	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	Q5EBH1, O70407, Q6KAR0, Q8C2E8	Gene names	Rassf5, Nore1, Rapl
Domain Architecture	No domain graphic available
Description	Ras association domain-containing family protein 5 (New ras effector 1) (Regulator for cell adhesion and polarization enriched in lymphoid tissues) (RAPL).

CR030_HUMAN
NC score	0.016070 (rank : 190)	θ value	6.88961 (rank : 185)
Query Neighborhood Hits	210	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N787	Gene names	C18orf30
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf30.

DNJC1_MOUSE
NC score	0.015410 (rank : 191)	θ value	6.88961 (rank : 187)
Query Neighborhood Hits	210	Target Neighborhood Hits	129	Shared Neighborhood Hits	4
SwissProt Accessions	Q61712	Gene names	Dnajc1, Dnajl1, Mtj1
Domain Architecture
Description	DnaJ homolog subfamily C member 1 (DnaJ protein homolog MTJ1).

JARD2_MOUSE
NC score	0.015246 (rank : 192)	θ value	5.27518 (rank : 174)
Query Neighborhood Hits	210	Target Neighborhood Hits	169	Shared Neighborhood Hits	10
SwissProt Accessions	Q62315, Q99LD1	Gene names	Jarid2, Jmj
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

ATX7_HUMAN
NC score	0.015218 (rank : 193)	θ value	5.27518 (rank : 171)
Query Neighborhood Hits	210	Target Neighborhood Hits	351	Shared Neighborhood Hits	8
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

ZN638_MOUSE
NC score	0.014968 (rank : 194)	θ value	6.88961 (rank : 194)
Query Neighborhood Hits	210	Target Neighborhood Hits	318	Shared Neighborhood Hits	15
SwissProt Accessions	Q61464, Q6DFV9, Q8C941	Gene names	Znf638, Np220, Zfml
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein).

K0146_MOUSE
NC score	0.014605 (rank : 195)	θ value	6.88961 (rank : 189)
Query Neighborhood Hits	210	Target Neighborhood Hits	57	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BGX7, Q3TCD0, Q5U457, Q6A0B6, Q6IS60, Q811E1, Q8BWD6, Q8R305	Gene names	Kiaa0146
Domain Architecture	No domain graphic available
Description	Protein KIAA0146.

MSH6_HUMAN
NC score	0.014410 (rank : 196)	θ value	4.03905 (rank : 165)
Query Neighborhood Hits	210	Target Neighborhood Hits	81	Shared Neighborhood Hits	8
SwissProt Accessions	P52701, O43706, O43917, Q8TCX4, Q9BTB5	Gene names	MSH6, GTBP
Domain Architecture
Description	DNA mismatch repair protein MSH6 (MutS-alpha 160 kDa subunit) (G/T mismatch-binding protein) (GTBP) (GTMBP) (p160).

TTC16_MOUSE
NC score	0.013992 (rank : 197)	θ value	8.99809 (rank : 209)
Query Neighborhood Hits	210	Target Neighborhood Hits	98	Shared Neighborhood Hits	9
SwissProt Accessions	Q8C1F5	Gene names	Ttc16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

EVC_HUMAN
NC score	0.013620 (rank : 198)	θ value	8.99809 (rank : 197)
Query Neighborhood Hits	210	Target Neighborhood Hits	129	Shared Neighborhood Hits	10
SwissProt Accessions	P57679	Gene names	EVC
Domain Architecture	No domain graphic available
Description	Ellis-van Creveld syndrome protein (DWF-1).

TEX14_MOUSE
NC score	0.013255 (rank : 199)	θ value	0.62314 (rank : 111)
Query Neighborhood Hits	210	Target Neighborhood Hits	1333	Shared Neighborhood Hits	38
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

ANK2_HUMAN
NC score	0.012852 (rank : 200)	θ value	1.38821 (rank : 124)
Query Neighborhood Hits	210	Target Neighborhood Hits	1615	Shared Neighborhood Hits	50
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

UBE3A_HUMAN
NC score	0.012739 (rank : 201)	θ value	1.06291 (rank : 122)
Query Neighborhood Hits	210	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	Q05086, P78355, Q93066, Q9UEP4, Q9UEP5, Q9UEP6, Q9UEP7, Q9UEP8, Q9UEP9	Gene names	UBE3A, E6AP
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (E6AP ubiquitin-protein ligase) (Oncogenic protein-associated protein E6-AP) (Human papillomavirus E6-associated protein) (NY-REN-54 antigen).

BRCA1_HUMAN
NC score	0.012171 (rank : 202)	θ value	3.0926 (rank : 153)
Query Neighborhood Hits	210	Target Neighborhood Hits	381	Shared Neighborhood Hits	10
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

RMI1_MOUSE
NC score	0.011636 (rank : 203)	θ value	8.99809 (rank : 202)
Query Neighborhood Hits	210	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D4G9, Q8C560, Q8CI20	Gene names	Rmi1
Domain Architecture	No domain graphic available
Description	Protein RMI1 homolog.

AL2SE_HUMAN
NC score	0.011144 (rank : 204)	θ value	6.88961 (rank : 183)
Query Neighborhood Hits	210	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NDH6, Q53P45, Q53QZ4, Q53T97, Q96N47, Q96Q32, Q9BVQ2	Gene names	ALS2CR15
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 15 protein.

ITA3_MOUSE
NC score	0.010572 (rank : 205)	θ value	1.38821 (rank : 127)
Query Neighborhood Hits	210	Target Neighborhood Hits	54	Shared Neighborhood Hits	2
SwissProt Accessions	Q62470, Q08441, Q08442	Gene names	Itga3
Domain Architecture
Description	Integrin alpha-3 precursor (Galactoprotein B3) (GAPB3) (VLA-3 alpha chain) (CD49c antigen) [Contains: Integrin alpha-3 heavy chain; Integrin alpha-3 light chain].

MAGC1_HUMAN
NC score	0.010512 (rank : 206)	θ value	2.36792 (rank : 146)
Query Neighborhood Hits	210	Target Neighborhood Hits	431	Shared Neighborhood Hits	13
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

ANK3_HUMAN
NC score	0.009690 (rank : 207)	θ value	8.99809 (rank : 196)
Query Neighborhood Hits	210	Target Neighborhood Hits	853	Shared Neighborhood Hits	44
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

THAP4_HUMAN
NC score	0.009416 (rank : 208)	θ value	8.99809 (rank : 207)
Query Neighborhood Hits	210	Target Neighborhood Hits	92	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WY91, Q53NU7, Q6GRN0, Q6IPJ3, Q9NW26, Q9Y325	Gene names	THAP4
Domain Architecture
Description	THAP domain-containing protein 4.

ATAD2_MOUSE
NC score	0.009243 (rank : 209)	θ value	3.0926 (rank : 152)
Query Neighborhood Hits	210	Target Neighborhood Hits	167	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CDM1	Gene names	Atad2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

GCP4_HUMAN
NC score	0.009234 (rank : 210)	θ value	8.99809 (rank : 200)
Query Neighborhood Hits	210	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UGJ1, Q969X3, Q9NVF0	Gene names	TUBGCP4, 76P, GCP4
Domain Architecture
Description	Gamma-tubulin complex component 4 (GCP-4) (hGCP4) (h76p) (Hgrip76).

CAN3_HUMAN
NC score	0.008968 (rank : 211)	θ value	1.81305 (rank : 129)
Query Neighborhood Hits	210	Target Neighborhood Hits	96	Shared Neighborhood Hits	3
SwissProt Accessions	P20807, Q9BTU4, Q9Y5S6, Q9Y5S7	Gene names	CAPN3, CANP3, CANPL3, NCL1
Domain Architecture
Description	Calpain-3 (EC 3.4.22.-) (Calpain L3) (Calpain p94) (Calcium-activated neutral proteinase 3) (CANP 3) (Muscle-specific calcium-activated neutral protease 3) (nCL-1).

AKAP3_HUMAN
NC score	0.008664 (rank : 212)	θ value	8.99809 (rank : 195)
Query Neighborhood Hits	210	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	O75969, O75945, Q9UM61	Gene names	AKAP3, AKAP110, SOB1
Domain Architecture
Description	A-kinase anchor protein 3 (Protein kinase A-anchoring protein 3) (PRKA3) (A-kinase anchor protein 110 kDa) (AKAP 110) (Sperm oocyte- binding protein) (Fibrousheathin-1) (Fibrousheathin I) (Fibrous sheath protein of 95 kDa) (FSP95).

GP112_HUMAN
NC score	0.008007 (rank : 213)	θ value	2.36792 (rank : 142)
Query Neighborhood Hits	210	Target Neighborhood Hits	441	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

ANKS1_MOUSE
NC score	0.006787 (rank : 214)	θ value	4.03905 (rank : 160)
Query Neighborhood Hits	210	Target Neighborhood Hits	453	Shared Neighborhood Hits	7
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

ARHG6_MOUSE
NC score	0.006237 (rank : 215)	θ value	5.27518 (rank : 170)
Query Neighborhood Hits	210	Target Neighborhood Hits	394	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

GRHL2_MOUSE
NC score	0.005956 (rank : 216)	θ value	8.99809 (rank : 201)
Query Neighborhood Hits	210	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K5C0, Q80UZ5	Gene names	Grhl2, Bom, Tcfcp2l3
Domain Architecture	No domain graphic available
Description	Grainyhead-like protein 2 homolog (Brother of mammalian grainyhead) (Transcription factor CP2-like 3).

KI13A_HUMAN
NC score	0.005678 (rank : 217)	θ value	5.27518 (rank : 175)
Query Neighborhood Hits	210	Target Neighborhood Hits	359	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H1H9, Q9H1H8	Gene names	KIF13A, RBKIN
Domain Architecture
Description	Kinesin-like protein KIF13A (Kinesin-like protein RBKIN).

MYO10_HUMAN
NC score	0.004788 (rank : 218)	θ value	5.27518 (rank : 179)
Query Neighborhood Hits	210	Target Neighborhood Hits	920	Shared Neighborhood Hits	28
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

FGD5_MOUSE
NC score	0.004078 (rank : 219)	θ value	8.99809 (rank : 199)
Query Neighborhood Hits	210	Target Neighborhood Hits	170	Shared Neighborhood Hits	5
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

TLR4_MOUSE
NC score	0.002803 (rank : 220)	θ value	5.27518 (rank : 182)
Query Neighborhood Hits	210	Target Neighborhood Hits	279	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QUK6, Q9D691, Q9QZF5, Q9Z203	Gene names	Tlr4, Lps
Domain Architecture
Description	Toll-like receptor 4 precursor (CD284 antigen).

GP152_HUMAN
NC score	0.002543 (rank : 221)	θ value	6.88961 (rank : 188)
Query Neighborhood Hits	210	Target Neighborhood Hits	636	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TDT2, Q86SM0	Gene names	GPR152, PGR5
Domain Architecture
Description	Probable G-protein coupled receptor 152 (G-protein coupled receptor PGR5).

CD2L7_HUMAN
NC score	0.000299 (rank : 222)	θ value	0.62314 (rank : 104)
Query Neighborhood Hits	210	Target Neighborhood Hits	1275	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

TPA_HUMAN
NC score	-0.001487 (rank : 223)	θ value	8.99809 (rank : 208)
Query Neighborhood Hits	210	Target Neighborhood Hits	324	Shared Neighborhood Hits	2
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

MAST1_HUMAN
NC score	-0.003821 (rank : 224)	θ value	5.27518 (rank : 178)
Query Neighborhood Hits	210	Target Neighborhood Hits	1146	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MTF1_HUMAN
NC score	-0.004088 (rank : 225)	θ value	4.03905 (rank : 166)
Query Neighborhood Hits	210	Target Neighborhood Hits	814	Shared Neighborhood Hits	5
SwissProt Accessions	Q14872, Q96CB1	Gene names	MTF1
Domain Architecture	No domain graphic available
Description	Metal-regulatory transcription factor 1 (Transcription factor MTF-1) (MRE-binding transcription factor).

EVI1_HUMAN
NC score	-0.004400 (rank : 226)	θ value	8.99809 (rank : 198)
Query Neighborhood Hits	210	Target Neighborhood Hits	924	Shared Neighborhood Hits	17
SwissProt Accessions	Q03112, Q16122, Q99917	Gene names	EVI1
Domain Architecture
Description	Ecotropic virus integration 1 site protein.

NEK4_HUMAN
NC score	-0.004611 (rank : 227)	θ value	6.88961 (rank : 191)
Query Neighborhood Hits	210	Target Neighborhood Hits	883	Shared Neighborhood Hits	6
SwissProt Accessions	P51957	Gene names	NEK4, STK2
Domain Architecture
Description	Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2) (Serine/threonine-protein kinase NRK2).

ZN471_HUMAN
NC score	-0.005752 (rank : 228)	θ value	8.99809 (rank : 210)
Query Neighborhood Hits	210	Target Neighborhood Hits	771	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BX82, O75260, Q8N3V1, Q9P2F1	Gene names	ZNF471, ERP1, KIAA1396
Domain Architecture
Description	Zinc finger protein 471 (EZFIT-related protein 1).