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Network neighborhood for query Sequence : DDX27_HUMAN

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DDX27_HUMAN
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DDX27_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	197	Target Neighborhood Hits	197	Shared Neighborhood Hits	197
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX27_MOUSE
θ value	0 (rank : 2)	NC score	0.995483 (rank : 2)
Query Neighborhood Hits	197	Target Neighborhood Hits	174	Shared Neighborhood Hits	128
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX47_HUMAN
θ value	1.35953e-72 (rank : 3)	NC score	0.977536 (rank : 4)
Query Neighborhood Hits	197	Target Neighborhood Hits	97	Shared Neighborhood Hits	87
SwissProt Accessions	Q9H0S4, Q96GM0, Q96NV8	Gene names	DDX47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX47_MOUSE
θ value	6.31527e-70 (rank : 4)	NC score	0.977661 (rank : 3)
Query Neighborhood Hits	197	Target Neighborhood Hits	97	Shared Neighborhood Hits	87
SwissProt Accessions	Q9CWX9	Gene names	Ddx47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX49_HUMAN
θ value	3.83135e-67 (rank : 5)	NC score	0.972115 (rank : 6)
Query Neighborhood Hits	197	Target Neighborhood Hits	223	Shared Neighborhood Hits	99
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX49_MOUSE
θ value	3.58603e-65 (rank : 6)	NC score	0.975263 (rank : 5)
Query Neighborhood Hits	197	Target Neighborhood Hits	119	Shared Neighborhood Hits	87
SwissProt Accessions	Q4FZF3	Gene names	Ddx49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX54_MOUSE
θ value	7.24236e-58 (rank : 7)	NC score	0.963870 (rank : 8)
Query Neighborhood Hits	197	Target Neighborhood Hits	124	Shared Neighborhood Hits	87
SwissProt Accessions	Q8K4L0	Gene names	Ddx54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54).

PL10_MOUSE
θ value	3.0428e-56 (rank : 8)	NC score	0.952753 (rank : 40)
Query Neighborhood Hits	197	Target Neighborhood Hits	120	Shared Neighborhood Hits	90
SwissProt Accessions	P16381	Gene names	D1Pas1, Pl10
Domain Architecture
Description	Putative ATP-dependent RNA helicase Pl10 (EC 3.6.1.-).

DDX3X_HUMAN
θ value	5.19021e-56 (rank : 9)	NC score	0.952640 (rank : 41)
Query Neighborhood Hits	197	Target Neighborhood Hits	122	Shared Neighborhood Hits	90
SwissProt Accessions	O00571, O15536	Gene names	DDX3X, DBX, DDX3
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (Helicase-like protein 2) (HLP2) (DEAD box, X isoform).

DDX10_HUMAN
θ value	1.15626e-55 (rank : 10)	NC score	0.955870 (rank : 35)
Query Neighborhood Hits	197	Target Neighborhood Hits	210	Shared Neighborhood Hits	100
SwissProt Accessions	Q13206, Q5BJD8	Gene names	DDX10
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX18_MOUSE
θ value	1.97229e-55 (rank : 11)	NC score	0.960235 (rank : 15)
Query Neighborhood Hits	197	Target Neighborhood Hits	115	Shared Neighborhood Hits	80
SwissProt Accessions	Q8K363, Q3MIB0, Q8BVZ2, Q9D2E0	Gene names	Ddx18
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18).

DDX3X_MOUSE
θ value	4.39379e-55 (rank : 12)	NC score	0.952090 (rank : 44)
Query Neighborhood Hits	197	Target Neighborhood Hits	117	Shared Neighborhood Hits	90
SwissProt Accessions	Q62167, O09060, O09143	Gene names	Ddx3x, D1Pas1-rs2, Ddx3, Dead3, Erh
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (DEAD box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1Pas1-related sequence 2).

DDX54_HUMAN
θ value	4.39379e-55 (rank : 13)	NC score	0.960058 (rank : 16)
Query Neighborhood Hits	197	Target Neighborhood Hits	170	Shared Neighborhood Hits	89
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).

DDX3Y_HUMAN
θ value	1.2784e-54 (rank : 14)	NC score	0.951164 (rank : 46)
Query Neighborhood Hits	197	Target Neighborhood Hits	121	Shared Neighborhood Hits	90
SwissProt Accessions	O15523, Q8IYV7	Gene names	DDX3Y, DBY
Domain Architecture
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal).

DDX23_HUMAN
θ value	2.18062e-54 (rank : 15)	NC score	0.941407 (rank : 54)
Query Neighborhood Hits	197	Target Neighborhood Hits	486	Shared Neighborhood Hits	132
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

DDX10_MOUSE
θ value	8.28633e-54 (rank : 16)	NC score	0.954363 (rank : 38)
Query Neighborhood Hits	197	Target Neighborhood Hits	233	Shared Neighborhood Hits	96
SwissProt Accessions	Q80Y44	Gene names	Ddx10
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX4_HUMAN
θ value	1.08223e-53 (rank : 17)	NC score	0.959960 (rank : 17)
Query Neighborhood Hits	197	Target Neighborhood Hits	123	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NQI0, Q86VX0, Q9NT92, Q9NYB1	Gene names	DDX4, VASA
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog).

DDX4_MOUSE
θ value	2.41096e-53 (rank : 18)	NC score	0.960679 (rank : 14)
Query Neighborhood Hits	197	Target Neighborhood Hits	100	Shared Neighborhood Hits	86
SwissProt Accessions	Q61496, Q9D5X7	Gene names	Ddx4, Vasa
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog) (Mvh).

DDX3Y_MOUSE
θ value	1.19655e-52 (rank : 19)	NC score	0.952260 (rank : 42)
Query Neighborhood Hits	197	Target Neighborhood Hits	126	Shared Neighborhood Hits	90
SwissProt Accessions	Q62095, Q9QWS9	Gene names	Ddx3y, D1Pas1-rs1, Dead2
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal) (DEAD-box RNA helicase DEAD2) (mDEAD2) (D1Pas1-related sequence 1).

DDX18_HUMAN
θ value	6.56568e-51 (rank : 20)	NC score	0.958064 (rank : 21)
Query Neighborhood Hits	197	Target Neighborhood Hits	124	Shared Neighborhood Hits	83
SwissProt Accessions	Q9NVP1, Q6IAU4, Q92732, Q9BQB7	Gene names	DDX18
Domain Architecture
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb).

DDX48_HUMAN
θ value	1.11993e-50 (rank : 21)	NC score	0.959321 (rank : 18)
Query Neighborhood Hits	197	Target Neighborhood Hits	102	Shared Neighborhood Hits	86
SwissProt Accessions	P38919, Q15033, Q96A18	Gene names	DDX48, EIF4A3, KIAA0111
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Nuclear matrix protein 265) (hNMP 265) (Eukaryotic translation initiation factor 4A isoform 3).

DDX48_MOUSE
θ value	1.46268e-50 (rank : 22)	NC score	0.959144 (rank : 20)
Query Neighborhood Hits	197	Target Neighborhood Hits	102	Shared Neighborhood Hits	86
SwissProt Accessions	Q91VC3	Gene names	Ddx48
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48).

DDX53_HUMAN
θ value	9.48078e-50 (rank : 23)	NC score	0.954869 (rank : 37)
Query Neighborhood Hits	197	Target Neighborhood Hits	124	Shared Neighborhood Hits	82
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

UAP56_HUMAN
θ value	2.1121e-49 (rank : 24)	NC score	0.956155 (rank : 33)
Query Neighborhood Hits	197	Target Neighborhood Hits	96	Shared Neighborhood Hits	85
SwissProt Accessions	Q13838, O43496, Q5RJ64, Q5RJ66, Q5ST94, Q5STB4, Q5STB5, Q5STB7, Q5STU4, Q5STU5, Q5STU6, Q5STU8, Q71V76	Gene names	BAT1, UAP56
Domain Architecture
Description	Spliceosome RNA helicase BAT1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (HLA-B-associated transcript-1).

UAP56_MOUSE
θ value	2.1121e-49 (rank : 25)	NC score	0.956131 (rank : 34)
Query Neighborhood Hits	197	Target Neighborhood Hits	96	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Z1N5, Q8HW97	Gene names	Bat1, Bat1a, Uap56
Domain Architecture	No domain graphic available
Description	Spliceosome RNA helicase Bat1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (HLA-B-associated transcript 1).

DDX39_HUMAN
θ value	4.70527e-49 (rank : 26)	NC score	0.957854 (rank : 22)
Query Neighborhood Hits	197	Target Neighborhood Hits	94	Shared Neighborhood Hits	86
SwissProt Accessions	O00148, Q9BVP6, Q9H5W0	Gene names	DDX39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39) (Nuclear RNA helicase URH49).

IF4A1_HUMAN
θ value	1.04822e-48 (rank : 27)	NC score	0.957122 (rank : 23)
Query Neighborhood Hits	197	Target Neighborhood Hits	106	Shared Neighborhood Hits	86
SwissProt Accessions	P60842, P04765, Q5U018, Q61516	Gene names	EIF4A1, DDX2A, EIF4A
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A1_MOUSE
θ value	1.04822e-48 (rank : 28)	NC score	0.957122 (rank : 24)
Query Neighborhood Hits	197	Target Neighborhood Hits	106	Shared Neighborhood Hits	86
SwissProt Accessions	P60843, P04765, Q61516	Gene names	Eif4a1, Ddx2a, Eif4a
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A2_HUMAN
θ value	1.788e-48 (rank : 29)	NC score	0.956811 (rank : 27)
Query Neighborhood Hits	197	Target Neighborhood Hits	102	Shared Neighborhood Hits	86
SwissProt Accessions	Q14240, Q96B90, Q96EA8	Gene names	EIF4A2, DDX2B
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A2_MOUSE
θ value	1.788e-48 (rank : 30)	NC score	0.956811 (rank : 28)
Query Neighborhood Hits	197	Target Neighborhood Hits	102	Shared Neighborhood Hits	86
SwissProt Accessions	P10630, Q61513, Q61514	Gene names	Eif4a2, Ddx2b
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

DDX5_HUMAN
θ value	2.3352e-48 (rank : 31)	NC score	0.952150 (rank : 43)
Query Neighborhood Hits	197	Target Neighborhood Hits	102	Shared Neighborhood Hits	87
SwissProt Accessions	P17844, O75681	Gene names	DDX5, HELR, HLR1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68).

DDX39_MOUSE
θ value	6.7944e-48 (rank : 32)	NC score	0.956971 (rank : 25)
Query Neighborhood Hits	197	Target Neighborhood Hits	97	Shared Neighborhood Hits	85
SwissProt Accessions	Q8VDW0, Q3UJV4, Q8C2C2	Gene names	Ddx39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39).

DDX5_MOUSE
θ value	6.7944e-48 (rank : 33)	NC score	0.952012 (rank : 45)
Query Neighborhood Hits	197	Target Neighborhood Hits	101	Shared Neighborhood Hits	87
SwissProt Accessions	Q61656	Gene names	Ddx5, Tnz2
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68) (DEAD box RNA helicase DEAD1) (mDEAD1).

DDX17_HUMAN
θ value	1.51363e-47 (rank : 34)	NC score	0.956327 (rank : 32)
Query Neighborhood Hits	197	Target Neighborhood Hits	104	Shared Neighborhood Hits	87
SwissProt Accessions	Q92841, Q69YT1, Q6ICD6	Gene names	DDX17
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17) (RNA-dependent helicase p72) (DEAD box protein p72).

DDX17_MOUSE
θ value	1.51363e-47 (rank : 35)	NC score	0.956464 (rank : 31)
Query Neighborhood Hits	197	Target Neighborhood Hits	105	Shared Neighborhood Hits	87
SwissProt Accessions	Q501J6, Q6P5G1, Q8BIN2	Gene names	Ddx17
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17).

DDX51_MOUSE
θ value	1.51363e-47 (rank : 36)	NC score	0.950033 (rank : 48)
Query Neighborhood Hits	197	Target Neighborhood Hits	130	Shared Neighborhood Hits	88
SwissProt Accessions	Q6P9R1, Q3U7M2	Gene names	Ddx51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX41_MOUSE
θ value	1.97686e-47 (rank : 37)	NC score	0.962239 (rank : 13)
Query Neighborhood Hits	197	Target Neighborhood Hits	115	Shared Neighborhood Hits	90
SwissProt Accessions	Q91VN6	Gene names	Ddx41
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41).

DDX41_HUMAN
θ value	2.58187e-47 (rank : 38)	NC score	0.962549 (rank : 12)
Query Neighborhood Hits	197	Target Neighborhood Hits	111	Shared Neighborhood Hits	90
SwissProt Accessions	Q9UJV9, Q96BK6, Q96K05, Q9NT96, Q9NW04	Gene names	DDX41, ABS
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41) (DEAD box protein abstrakt homolog).

DDX52_HUMAN
θ value	3.37202e-47 (rank : 39)	NC score	0.964046 (rank : 7)
Query Neighborhood Hits	197	Target Neighborhood Hits	107	Shared Neighborhood Hits	88
SwissProt Accessions	Q9Y2R4, Q86YG1, Q8N213, Q9NVE0, Q9Y482	Gene names	DDX52, ROK1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX52_MOUSE
θ value	2.85459e-46 (rank : 40)	NC score	0.963697 (rank : 9)
Query Neighborhood Hits	197	Target Neighborhood Hits	101	Shared Neighborhood Hits	88
SwissProt Accessions	Q8K301, Q8BV29	Gene names	Ddx52, Rok1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX46_HUMAN
θ value	6.35935e-46 (rank : 41)	NC score	0.943078 (rank : 50)
Query Neighborhood Hits	197	Target Neighborhood Hits	357	Shared Neighborhood Hits	124
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

DDX46_MOUSE
θ value	6.35935e-46 (rank : 42)	NC score	0.941084 (rank : 55)
Query Neighborhood Hits	197	Target Neighborhood Hits	358	Shared Neighborhood Hits	121
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

DDX31_HUMAN
θ value	3.15612e-45 (rank : 43)	NC score	0.953492 (rank : 39)
Query Neighborhood Hits	197	Target Neighborhood Hits	132	Shared Neighborhood Hits	85
SwissProt Accessions	Q9H8H2, Q5K6N2, Q5K6N3, Q5K6N4, Q5VZJ4, Q5VZJ9, Q96E91, Q96NY2, Q96SX5, Q9H5K6	Gene names	DDX31
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX31 (EC 3.6.1.-) (DEAD box protein 31) (Helicain).

DDX56_MOUSE
θ value	3.15612e-45 (rank : 44)	NC score	0.956506 (rank : 30)
Query Neighborhood Hits	197	Target Neighborhood Hits	87	Shared Neighborhood Hits	73
SwissProt Accessions	Q9D0R4	Gene names	Ddx56, D11Ertd619e, Noh61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase).

DDX6_HUMAN
θ value	4.122e-45 (rank : 45)	NC score	0.962954 (rank : 10)
Query Neighborhood Hits	197	Target Neighborhood Hits	97	Shared Neighborhood Hits	85
SwissProt Accessions	P26196	Gene names	DDX6, HLR2, RCK
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK).

DDX6_MOUSE
θ value	4.122e-45 (rank : 46)	NC score	0.962717 (rank : 11)
Query Neighborhood Hits	197	Target Neighborhood Hits	98	Shared Neighborhood Hits	85
SwissProt Accessions	P54823	Gene names	Ddx6, Hlr2, Rck
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK homolog).

DDX56_HUMAN
θ value	2.04573e-44 (rank : 47)	NC score	0.956880 (rank : 26)
Query Neighborhood Hits	197	Target Neighborhood Hits	77	Shared Neighborhood Hits	73
SwissProt Accessions	Q9NY93, Q9H9I8	Gene names	DDX56, DDX21, NOH61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD-box protein 21).

DDX51_HUMAN
θ value	5.95217e-44 (rank : 48)	NC score	0.934128 (rank : 63)
Query Neighborhood Hits	197	Target Neighborhood Hits	332	Shared Neighborhood Hits	88
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX43_HUMAN
θ value	6.58091e-43 (rank : 49)	NC score	0.959219 (rank : 19)
Query Neighborhood Hits	197	Target Neighborhood Hits	120	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NXZ2, Q6NXR1	Gene names	DDX43, HAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.1.-) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen).

DDX55_MOUSE
θ value	1.3722e-40 (rank : 50)	NC score	0.956752 (rank : 29)
Query Neighborhood Hits	197	Target Neighborhood Hits	111	Shared Neighborhood Hits	87
SwissProt Accessions	Q6ZPL9, Q149H5, Q3U460, Q8BZR1	Gene names	Ddx55, Kiaa1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX55_HUMAN
θ value	1.98146e-39 (rank : 51)	NC score	0.955415 (rank : 36)
Query Neighborhood Hits	197	Target Neighborhood Hits	122	Shared Neighborhood Hits	88
SwissProt Accessions	Q8NHQ9, Q658L6, Q9HCH7	Gene names	DDX55, KIAA1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DD19B_HUMAN
θ value	2.58786e-39 (rank : 52)	NC score	0.935995 (rank : 61)
Query Neighborhood Hits	197	Target Neighborhood Hits	109	Shared Neighborhood Hits	88
SwissProt Accessions	Q9UMR2, Q6FIB7, Q6IAE0	Gene names	DDX19B, DBP5, DDX19
Domain Architecture
Description	ATP-dependent RNA helicase DDX19B (EC 3.6.1.-) (DEAD box protein 19B) (DEAD box RNA helicase DEAD5).

DDX25_MOUSE
θ value	7.52953e-39 (rank : 53)	NC score	0.937611 (rank : 57)
Query Neighborhood Hits	197	Target Neighborhood Hits	98	Shared Neighborhood Hits	85
SwissProt Accessions	Q9QY15, Q8R1B6	Gene names	Ddx25, Grth
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX20_HUMAN
θ value	1.28434e-38 (rank : 54)	NC score	0.942180 (rank : 51)
Query Neighborhood Hits	197	Target Neighborhood Hits	121	Shared Neighborhood Hits	89
SwissProt Accessions	Q9UHI6, Q96F72, Q9NVM3, Q9UF59, Q9UIY0, Q9Y659	Gene names	DDX20, DP103, GEMIN3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3).

DD19A_MOUSE
θ value	2.86122e-38 (rank : 55)	NC score	0.936213 (rank : 60)
Query Neighborhood Hits	197	Target Neighborhood Hits	105	Shared Neighborhood Hits	89
SwissProt Accessions	Q61655, Q921R0	Gene names	Ddx19a, Ddx19, Eif4a-rs1
Domain Architecture
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DEAD box RNA helicase DEAD5) (mDEAD5) (Eukaryotic translation initiation factor 4A-related sequence 1).

DD19A_HUMAN
θ value	4.88048e-38 (rank : 56)	NC score	0.936558 (rank : 59)
Query Neighborhood Hits	197	Target Neighborhood Hits	107	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NUU7, Q53FM0	Gene names	DDX19A, DDX19L
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DDX19-like protein).

DDX20_MOUSE
θ value	8.32485e-38 (rank : 57)	NC score	0.938748 (rank : 56)
Query Neighborhood Hits	197	Target Neighborhood Hits	177	Shared Neighborhood Hits	91
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

DDX21_MOUSE
θ value	1.85459e-37 (rank : 58)	NC score	0.925635 (rank : 66)
Query Neighborhood Hits	197	Target Neighborhood Hits	350	Shared Neighborhood Hits	108
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX25_HUMAN
θ value	1.20211e-36 (rank : 59)	NC score	0.937444 (rank : 58)
Query Neighborhood Hits	197	Target Neighborhood Hits	93	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UHL0, Q86W81, Q8IYP1	Gene names	DDX25, GRTH
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX50_HUMAN
θ value	1.32909e-35 (rank : 60)	NC score	0.941717 (rank : 52)
Query Neighborhood Hits	197	Target Neighborhood Hits	132	Shared Neighborhood Hits	89
SwissProt Accessions	Q9BQ39, Q8WV76, Q9BWI8	Gene names	DDX50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX50_MOUSE
θ value	1.32909e-35 (rank : 61)	NC score	0.941667 (rank : 53)
Query Neighborhood Hits	197	Target Neighborhood Hits	137	Shared Neighborhood Hits	89
SwissProt Accessions	Q99MJ9	Gene names	Ddx50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX21_HUMAN
θ value	1.73584e-35 (rank : 62)	NC score	0.932895 (rank : 65)
Query Neighborhood Hits	197	Target Neighborhood Hits	308	Shared Neighborhood Hits	113
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX24_HUMAN
θ value	6.17384e-33 (rank : 63)	NC score	0.932956 (rank : 64)
Query Neighborhood Hits	197	Target Neighborhood Hits	190	Shared Neighborhood Hits	89
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX24_MOUSE
θ value	8.06329e-33 (rank : 64)	NC score	0.935638 (rank : 62)
Query Neighborhood Hits	197	Target Neighborhood Hits	147	Shared Neighborhood Hits	92
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX28_MOUSE
θ value	1.98606e-31 (rank : 65)	NC score	0.950838 (rank : 47)
Query Neighborhood Hits	197	Target Neighborhood Hits	112	Shared Neighborhood Hits	89
SwissProt Accessions	Q9CWT6, Q3TQM0	Gene names	Ddx28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX28_HUMAN
θ value	5.40856e-29 (rank : 66)	NC score	0.946277 (rank : 49)
Query Neighborhood Hits	197	Target Neighborhood Hits	103	Shared Neighborhood Hits	84
SwissProt Accessions	Q9NUL7	Gene names	DDX28, MDDX28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX1_MOUSE
θ value	7.56453e-23 (rank : 67)	NC score	0.885935 (rank : 67)
Query Neighborhood Hits	197	Target Neighborhood Hits	112	Shared Neighborhood Hits	83
SwissProt Accessions	Q91VR5, Q3TU41	Gene names	Ddx1
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1).

DDX1_HUMAN
θ value	9.87957e-23 (rank : 68)	NC score	0.882894 (rank : 68)
Query Neighborhood Hits	197	Target Neighborhood Hits	110	Shared Neighborhood Hits	83
SwissProt Accessions	Q92499	Gene names	DDX1
Domain Architecture
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB).

RECQ5_HUMAN
θ value	3.29651e-10 (rank : 69)	NC score	0.482749 (rank : 72)
Query Neighborhood Hits	197	Target Neighborhood Hits	390	Shared Neighborhood Hits	80
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

FANCM_HUMAN
θ value	3.41135e-07 (rank : 70)	NC score	0.458660 (rank : 75)
Query Neighborhood Hits	197	Target Neighborhood Hits	210	Shared Neighborhood Hits	87
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

RECQ1_HUMAN
θ value	1.43324e-05 (rank : 71)	NC score	0.444265 (rank : 78)
Query Neighborhood Hits	197	Target Neighborhood Hits	100	Shared Neighborhood Hits	73
SwissProt Accessions	P46063	Gene names	RECQL, RECQL1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

LGP2_MOUSE
θ value	2.44474e-05 (rank : 72)	NC score	0.366860 (rank : 82)
Query Neighborhood Hits	197	Target Neighborhood Hits	86	Shared Neighborhood Hits	71
SwissProt Accessions	Q99J87, Q9D1X4	Gene names	Lgp2, D11lgp2e
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2).

RECQ1_MOUSE
θ value	4.1701e-05 (rank : 73)	NC score	0.443646 (rank : 79)
Query Neighborhood Hits	197	Target Neighborhood Hits	95	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Z129, Q9Z128	Gene names	Recql, Recql1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

DICER_MOUSE
θ value	7.1131e-05 (rank : 74)	NC score	0.424975 (rank : 81)
Query Neighborhood Hits	197	Target Neighborhood Hits	140	Shared Neighborhood Hits	84
SwissProt Accessions	Q8R418	Gene names	Dicer1, Dicer, Mdcr
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Double-strand-specific ribonuclease mDCR-1).

FANCM_MOUSE
θ value	7.1131e-05 (rank : 75)	NC score	0.453489 (rank : 76)
Query Neighborhood Hits	197	Target Neighborhood Hits	177	Shared Neighborhood Hits	84
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

RECQ4_MOUSE
θ value	7.1131e-05 (rank : 76)	NC score	0.536427 (rank : 70)
Query Neighborhood Hits	197	Target Neighborhood Hits	206	Shared Neighborhood Hits	85
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

LGP2_HUMAN
θ value	9.29e-05 (rank : 77)	NC score	0.352743 (rank : 84)
Query Neighborhood Hits	197	Target Neighborhood Hits	94	Shared Neighborhood Hits	72
SwissProt Accessions	Q96C10, Q9HAM6	Gene names	LGP2, D11LGP2E
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2 homolog).

DICER_HUMAN
θ value	0.000121331 (rank : 78)	NC score	0.425719 (rank : 80)
Query Neighborhood Hits	197	Target Neighborhood Hits	126	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UPY3, O95943, Q9UQ02	Gene names	DICER1, DICER, HERNA, KIAA0928
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Helicase with RNase motif) (Helicase-MOI).

RECQ4_HUMAN
θ value	0.000158464 (rank : 79)	NC score	0.554214 (rank : 69)
Query Neighborhood Hits	197	Target Neighborhood Hits	177	Shared Neighborhood Hits	85
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

WRN_MOUSE
θ value	0.000158464 (rank : 80)	NC score	0.445662 (rank : 77)
Query Neighborhood Hits	197	Target Neighborhood Hits	295	Shared Neighborhood Hits	95
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

WRN_HUMAN
θ value	0.000461057 (rank : 81)	NC score	0.474744 (rank : 74)
Query Neighborhood Hits	197	Target Neighborhood Hits	132	Shared Neighborhood Hits	83
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

IFIH1_MOUSE
θ value	0.00134147 (rank : 82)	NC score	0.343121 (rank : 85)
Query Neighborhood Hits	197	Target Neighborhood Hits	126	Shared Neighborhood Hits	82
SwissProt Accessions	Q8R5F7, Q3U6S2, Q68EM4, Q8BYC9, Q8BZ01, Q8K5C7, Q8R144, Q8VE79, Q99KS4, Q9D2Z5	Gene names	Ifih1
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5).

PHF20_HUMAN
θ value	0.00509761 (rank : 83)	NC score	0.052850 (rank : 94)
Query Neighborhood Hits	197	Target Neighborhood Hits	394	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

IFIH1_HUMAN
θ value	0.00665767 (rank : 84)	NC score	0.356642 (rank : 83)
Query Neighborhood Hits	197	Target Neighborhood Hits	96	Shared Neighborhood Hits	76
SwissProt Accessions	Q9BYX4, Q6DC96, Q86X56, Q96MX8, Q9H3G6	Gene names	IFIH1, MDA5, RH116
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon-induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5) (RNA helicase-DEAD box protein 116) (Murabutide-down- regulated protein).

BLM_MOUSE
θ value	0.00869519 (rank : 85)	NC score	0.496751 (rank : 71)
Query Neighborhood Hits	197	Target Neighborhood Hits	108	Shared Neighborhood Hits	72
SwissProt Accessions	O88700, O88198	Gene names	Blm
Domain Architecture
Description	Bloom syndrome protein homolog (EC 3.6.1.-) (mBLM).

PHF20_MOUSE
θ value	0.0148317 (rank : 86)	NC score	0.060146 (rank : 93)
Query Neighborhood Hits	197	Target Neighborhood Hits	513	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

BLM_HUMAN
θ value	0.0193708 (rank : 87)	NC score	0.482016 (rank : 73)
Query Neighborhood Hits	197	Target Neighborhood Hits	148	Shared Neighborhood Hits	77
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

GOGA4_MOUSE
θ value	0.0252991 (rank : 88)	NC score	0.021323 (rank : 122)
Query Neighborhood Hits	197	Target Neighborhood Hits	1939	Shared Neighborhood Hits	76
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

CCD41_MOUSE
θ value	0.0431538 (rank : 89)	NC score	0.024676 (rank : 112)
Query Neighborhood Hits	197	Target Neighborhood Hits	1399	Shared Neighborhood Hits	64
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

DDX58_MOUSE
θ value	0.0431538 (rank : 90)	NC score	0.230132 (rank : 86)
Query Neighborhood Hits	197	Target Neighborhood Hits	99	Shared Neighborhood Hits	64
SwissProt Accessions	Q6Q899, Q8C320, Q8C5I3, Q8C7T2	Gene names	Ddx58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

MYH9_MOUSE
θ value	0.0431538 (rank : 91)	NC score	0.019987 (rank : 128)
Query Neighborhood Hits	197	Target Neighborhood Hits	1829	Shared Neighborhood Hits	77
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

ADA30_HUMAN
θ value	0.0961366 (rank : 92)	NC score	0.008531 (rank : 185)
Query Neighborhood Hits	197	Target Neighborhood Hits	391	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

CP250_HUMAN
θ value	0.0961366 (rank : 93)	NC score	0.019746 (rank : 132)
Query Neighborhood Hits	197	Target Neighborhood Hits	1805	Shared Neighborhood Hits	67
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

MYH9_HUMAN
θ value	0.0961366 (rank : 94)	NC score	0.018447 (rank : 140)
Query Neighborhood Hits	197	Target Neighborhood Hits	1762	Shared Neighborhood Hits	77
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

CT2NL_HUMAN
θ value	0.125558 (rank : 95)	NC score	0.036204 (rank : 100)
Query Neighborhood Hits	197	Target Neighborhood Hits	1059	Shared Neighborhood Hits	61
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

KTN1_MOUSE
θ value	0.125558 (rank : 96)	NC score	0.020540 (rank : 127)
Query Neighborhood Hits	197	Target Neighborhood Hits	1324	Shared Neighborhood Hits	68
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

NFH_HUMAN
θ value	0.163984 (rank : 97)	NC score	0.012653 (rank : 173)
Query Neighborhood Hits	197	Target Neighborhood Hits	1242	Shared Neighborhood Hits	78
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

CJ118_MOUSE
θ value	0.21417 (rank : 98)	NC score	0.021106 (rank : 124)
Query Neighborhood Hits	197	Target Neighborhood Hits	1132	Shared Neighborhood Hits	64
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

CYBP_HUMAN
θ value	0.21417 (rank : 99)	NC score	0.029122 (rank : 105)
Query Neighborhood Hits	197	Target Neighborhood Hits	23	Shared Neighborhood Hits	6
SwissProt Accessions	Q9HB71, O60666	Gene names	CACYBP, S100A6BP, SIP
Domain Architecture
Description	Calcyclin-binding protein (CacyBP) (hCacyBP) (Siah-interacting protein) (S100A6-binding protein).

MD1L1_HUMAN
θ value	0.21417 (rank : 100)	NC score	0.021374 (rank : 121)
Query Neighborhood Hits	197	Target Neighborhood Hits	893	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

SM1L2_MOUSE
θ value	0.21417 (rank : 101)	NC score	0.019906 (rank : 131)
Query Neighborhood Hits	197	Target Neighborhood Hits	918	Shared Neighborhood Hits	55
SwissProt Accessions	Q920F6	Gene names	Smc1l2
Domain Architecture
Description	Structural maintenance of chromosomes 1-like 2 protein (SMC1beta protein).

TCAL3_HUMAN
θ value	0.21417 (rank : 102)	NC score	0.027452 (rank : 109)
Query Neighborhood Hits	197	Target Neighborhood Hits	274	Shared Neighborhood Hits	17
SwissProt Accessions	Q969E4	Gene names	TCEAL3
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 3 (TCEA-like protein 3) (Transcription elongation factor S-II protein-like 3).

AP4E1_HUMAN
θ value	0.279714 (rank : 103)	NC score	0.010794 (rank : 179)
Query Neighborhood Hits	197	Target Neighborhood Hits	57	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPM8, Q9Y588	Gene names	AP4E1
Domain Architecture
Description	AP-4 complex subunit epsilon-1 (Adapter-related protein complex 4 epsilon-1 subunit) (Epsilon subunit of AP-4) (AP-4 adapter complex epsilon subunit).

EPN4_MOUSE
θ value	0.279714 (rank : 104)	NC score	0.023666 (rank : 115)
Query Neighborhood Hits	197	Target Neighborhood Hits	58	Shared Neighborhood Hits	6
SwissProt Accessions	Q99KN9, Q8CFH4	Gene names	Clint1, Enth, Epn4, Epnr, Kiaa0171
Domain Architecture
Description	Clathrin interactor 1 (Epsin-4) (Epsin-related protein) (EpsinR) (Enthoprotin).

NIN_MOUSE
θ value	0.279714 (rank : 105)	NC score	0.016976 (rank : 143)
Query Neighborhood Hits	197	Target Neighborhood Hits	1376	Shared Neighborhood Hits	57
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

TCAL5_HUMAN
θ value	0.365318 (rank : 106)	NC score	0.028251 (rank : 107)
Query Neighborhood Hits	197	Target Neighborhood Hits	806	Shared Neighborhood Hits	42
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

CHD3_HUMAN
θ value	0.47712 (rank : 107)	NC score	0.039929 (rank : 98)
Query Neighborhood Hits	197	Target Neighborhood Hits	397	Shared Neighborhood Hits	37
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

ATRX_HUMAN
θ value	0.62314 (rank : 108)	NC score	0.029263 (rank : 104)
Query Neighborhood Hits	197	Target Neighborhood Hits	842	Shared Neighborhood Hits	73
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

EPN4_HUMAN
θ value	0.62314 (rank : 109)	NC score	0.021237 (rank : 123)
Query Neighborhood Hits	197	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	Q14677, Q8NAF1, Q96E05	Gene names	CLINT1, ENTH, EPN4, EPNR, KIAA0171
Domain Architecture
Description	Clathrin interactor 1 (Epsin-4) (Epsin-related protein) (EpsinR) (Enthoprotin) (Clathrin-interacting protein localized in the trans- Golgi region) (Clint).

GOGA4_HUMAN
θ value	0.62314 (rank : 110)	NC score	0.026172 (rank : 111)
Query Neighborhood Hits	197	Target Neighborhood Hits	2034	Shared Neighborhood Hits	85
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

OVGP1_HUMAN
θ value	0.62314 (rank : 111)	NC score	0.013484 (rank : 170)
Query Neighborhood Hits	197	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	Q12889, Q15841	Gene names	OVGP1, MUC9, OGP
Domain Architecture
Description	Oviduct-specific glycoprotein precursor (Oviductal glycoprotein) (Oviductin) (Estrogen-dependent oviduct protein) (Mucin 9).

SETX_HUMAN
θ value	0.62314 (rank : 112)	NC score	0.018960 (rank : 137)
Query Neighborhood Hits	197	Target Neighborhood Hits	368	Shared Neighborhood Hits	27
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

ZN181_HUMAN
θ value	0.62314 (rank : 113)	NC score	-0.006539 (rank : 202)
Query Neighborhood Hits	197	Target Neighborhood Hits	764	Shared Neighborhood Hits	5
SwissProt Accessions	Q2M3W8, Q49A75	Gene names	ZNF181
Domain Architecture	No domain graphic available
Description	Zinc finger protein 181 (HHZ181).

MAP1A_HUMAN
θ value	0.813845 (rank : 114)	NC score	0.024526 (rank : 113)
Query Neighborhood Hits	197	Target Neighborhood Hits	1626	Shared Neighborhood Hits	77
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

RBM28_MOUSE
θ value	0.813845 (rank : 115)	NC score	0.006736 (rank : 188)
Query Neighborhood Hits	197	Target Neighborhood Hits	368	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CGC6, Q8BG25, Q8VEJ8, Q9CS22, Q9CSE6	Gene names	Rbm28
Domain Architecture	No domain graphic available
Description	RNA-binding protein 28 (RNA-binding motif protein 28).

TRHY_HUMAN
θ value	0.813845 (rank : 116)	NC score	0.020993 (rank : 126)
Query Neighborhood Hits	197	Target Neighborhood Hits	1385	Shared Neighborhood Hits	72
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

WAPL_MOUSE
θ value	0.813845 (rank : 117)	NC score	0.016665 (rank : 145)
Query Neighborhood Hits	197	Target Neighborhood Hits	158	Shared Neighborhood Hits	12
SwissProt Accessions	Q65Z40, Q6ZQE9	Gene names	Wapal, Kiaa0261, Wapl
Domain Architecture	No domain graphic available
Description	Wings apart-like protein homolog (Dioxin-inducible factor 2) (DIF-2).

AZI1_HUMAN
θ value	1.06291 (rank : 118)	NC score	0.019914 (rank : 130)
Query Neighborhood Hits	197	Target Neighborhood Hits	1000	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

CING_HUMAN
θ value	1.06291 (rank : 119)	NC score	0.018658 (rank : 138)
Query Neighborhood Hits	197	Target Neighborhood Hits	1275	Shared Neighborhood Hits	61
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

CT2NL_MOUSE
θ value	1.06291 (rank : 120)	NC score	0.033795 (rank : 103)
Query Neighborhood Hits	197	Target Neighborhood Hits	902	Shared Neighborhood Hits	60
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

KI21A_HUMAN
θ value	1.06291 (rank : 121)	NC score	0.013948 (rank : 167)
Query Neighborhood Hits	197	Target Neighborhood Hits	1543	Shared Neighborhood Hits	75
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

LEO1_HUMAN
θ value	1.06291 (rank : 122)	NC score	0.034333 (rank : 102)
Query Neighborhood Hits	197	Target Neighborhood Hits	958	Shared Neighborhood Hits	56
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

RPGR_HUMAN
θ value	1.06291 (rank : 123)	NC score	0.014301 (rank : 166)
Query Neighborhood Hits	197	Target Neighborhood Hits	279	Shared Neighborhood Hits	28
SwissProt Accessions	Q92834, O00702, O00737, Q8N5T6, Q93039, Q9HD29, Q9UMR1	Gene names	RPGR, RP3, XLRP3
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator.

RTN4_HUMAN
θ value	1.06291 (rank : 124)	NC score	0.012062 (rank : 177)
Query Neighborhood Hits	197	Target Neighborhood Hits	357	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

STK10_MOUSE
θ value	1.06291 (rank : 125)	NC score	0.002544 (rank : 196)
Query Neighborhood Hits	197	Target Neighborhood Hits	2132	Shared Neighborhood Hits	76
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

T3JAM_HUMAN
θ value	1.06291 (rank : 126)	NC score	0.017527 (rank : 142)
Query Neighborhood Hits	197	Target Neighborhood Hits	533	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Y228, Q2YDB5, Q4VY06, Q7Z706	Gene names	TRAF3IP3, T3JAM
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

CP135_HUMAN
θ value	1.38821 (rank : 127)	NC score	0.015306 (rank : 160)
Query Neighborhood Hits	197	Target Neighborhood Hits	1290	Shared Neighborhood Hits	63
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

HMMR_MOUSE
θ value	1.38821 (rank : 128)	NC score	0.017947 (rank : 141)
Query Neighborhood Hits	197	Target Neighborhood Hits	1178	Shared Neighborhood Hits	65
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

MDM2_MOUSE
θ value	1.38821 (rank : 129)	NC score	0.010554 (rank : 180)
Query Neighborhood Hits	197	Target Neighborhood Hits	77	Shared Neighborhood Hits	4
SwissProt Accessions	P23804, Q61040, Q64330	Gene names	Mdm2
Domain Architecture
Description	Ubiquitin-protein ligase E3 Mdm2 (EC 6.3.2.-) (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein).

ZN302_HUMAN
θ value	1.38821 (rank : 130)	NC score	-0.006593 (rank : 203)
Query Neighborhood Hits	197	Target Neighborhood Hits	755	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NR11, Q9BZD8, Q9P0J4	Gene names	ZNF302, ZNF135L, ZNF140L
Domain Architecture
Description	Zinc finger protein 302 (ZNF135-like) (ZNF140-like).

F10A5_HUMAN
θ value	1.81305 (rank : 131)	NC score	0.014598 (rank : 164)
Query Neighborhood Hits	197	Target Neighborhood Hits	277	Shared Neighborhood Hits	20
SwissProt Accessions	Q8NFI4	Gene names	FAM10A5
Domain Architecture	No domain graphic available
Description	Protein FAM10A5.

HERC2_HUMAN
θ value	1.81305 (rank : 132)	NC score	0.005125 (rank : 192)
Query Neighborhood Hits	197	Target Neighborhood Hits	163	Shared Neighborhood Hits	7
SwissProt Accessions	O95714, Q86SV7, Q86SV8, Q86SV9, Q86YY3, Q86YY4, Q86YY5, Q86YY6, Q86YY7, Q86YY8, Q86YY9, Q86YZ0, Q86YZ1	Gene names	HERC2
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

REST_MOUSE
θ value	1.81305 (rank : 133)	NC score	0.016430 (rank : 148)
Query Neighborhood Hits	197	Target Neighborhood Hits	1506	Shared Neighborhood Hits	73
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

SDPR_MOUSE
θ value	1.81305 (rank : 134)	NC score	0.022385 (rank : 118)
Query Neighborhood Hits	197	Target Neighborhood Hits	485	Shared Neighborhood Hits	42
SwissProt Accessions	Q63918, Q3V1P6, Q78EC3, Q8CBT4	Gene names	Sdpr, Sdr
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein).

TUFT1_MOUSE
θ value	1.81305 (rank : 135)	NC score	0.018979 (rank : 136)
Query Neighborhood Hits	197	Target Neighborhood Hits	732	Shared Neighborhood Hits	51
SwissProt Accessions	O08970	Gene names	Tuft1
Domain Architecture
Description	Tuftelin.

KINH_HUMAN
θ value	2.36792 (rank : 136)	NC score	0.015814 (rank : 155)
Query Neighborhood Hits	197	Target Neighborhood Hits	1231	Shared Neighborhood Hits	67
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

NEST_HUMAN
θ value	2.36792 (rank : 137)	NC score	0.015392 (rank : 158)
Query Neighborhood Hits	197	Target Neighborhood Hits	1305	Shared Neighborhood Hits	60
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

SAFB2_HUMAN
θ value	2.36792 (rank : 138)	NC score	0.021095 (rank : 125)
Query Neighborhood Hits	197	Target Neighborhood Hits	720	Shared Neighborhood Hits	54
SwissProt Accessions	Q14151, Q8TB13	Gene names	SAFB2, KIAA0138
Domain Architecture
Description	Scaffold attachment factor B2.

STMN1_MOUSE
θ value	2.36792 (rank : 139)	NC score	0.027592 (rank : 108)
Query Neighborhood Hits	197	Target Neighborhood Hits	560	Shared Neighborhood Hits	53
SwissProt Accessions	P54227	Gene names	Stmn1, Lag, Lap18, Pr22
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Pr22 protein) (Leukemia-associated gene protein).

TRIPB_HUMAN
θ value	2.36792 (rank : 140)	NC score	0.015837 (rank : 153)
Query Neighborhood Hits	197	Target Neighborhood Hits	1587	Shared Neighborhood Hits	65
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

CHD4_HUMAN
θ value	3.0926 (rank : 141)	NC score	0.045564 (rank : 96)
Query Neighborhood Hits	197	Target Neighborhood Hits	365	Shared Neighborhood Hits	45
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD4_MOUSE
θ value	3.0926 (rank : 142)	NC score	0.044968 (rank : 97)
Query Neighborhood Hits	197	Target Neighborhood Hits	408	Shared Neighborhood Hits	41
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

ERCC4_MOUSE
θ value	3.0926 (rank : 143)	NC score	0.015831 (rank : 154)
Query Neighborhood Hits	197	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QZD4, O54810, Q8R0I3	Gene names	Ercc4
Domain Architecture
Description	DNA repair endonuclease XPF (EC 3.1.-.-) (DNA excision repair protein ERCC-4).

GOGA6_HUMAN
θ value	3.0926 (rank : 144)	NC score	0.016015 (rank : 150)
Query Neighborhood Hits	197	Target Neighborhood Hits	1007	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

STMN1_HUMAN
θ value	3.0926 (rank : 145)	NC score	0.026280 (rank : 110)
Query Neighborhood Hits	197	Target Neighborhood Hits	554	Shared Neighborhood Hits	51
SwissProt Accessions	P16949	Gene names	STMN1, LAP18, OP18
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Protein Pr22).

BCAR1_HUMAN
θ value	4.03905 (rank : 146)	NC score	0.001975 (rank : 197)
Query Neighborhood Hits	197	Target Neighborhood Hits	554	Shared Neighborhood Hits	3
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

BCAS1_HUMAN
θ value	4.03905 (rank : 147)	NC score	0.007755 (rank : 187)
Query Neighborhood Hits	197	Target Neighborhood Hits	133	Shared Neighborhood Hits	7
SwissProt Accessions	O75363, Q68CZ3	Gene names	BCAS1, AIBC1, NABC1
Domain Architecture	No domain graphic available
Description	Breast carcinoma amplified sequence 1 (Novel amplified in breast cancer 1) (Amplified and overexpressed in breast cancer).

CA051_MOUSE
θ value	4.03905 (rank : 148)	NC score	0.014989 (rank : 162)
Query Neighborhood Hits	197	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q3TQ03, Q3U1B8	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf51 homolog.

F10A1_HUMAN
θ value	4.03905 (rank : 149)	NC score	0.010304 (rank : 181)
Query Neighborhood Hits	197	Target Neighborhood Hits	312	Shared Neighborhood Hits	22
SwissProt Accessions	P50502, O14999	Gene names	ST13, FAM10A1, HIP, SNC6
Domain Architecture
Description	Hsc70-interacting protein (Hip) (Suppression of tumorigenicity protein 13) (Putative tumor suppressor ST13) (Protein FAM10A1) (Progesterone receptor-associated p48 protein) (NY-REN-33 antigen).

K0831_HUMAN
θ value	4.03905 (rank : 150)	NC score	0.011957 (rank : 178)
Query Neighborhood Hits	197	Target Neighborhood Hits	203	Shared Neighborhood Hits	27
SwissProt Accessions	Q6ZNE5, O94920	Gene names	KIAA0831
Domain Architecture	No domain graphic available
Description	Protein KIAA0831.

MD1L1_MOUSE
θ value	4.03905 (rank : 151)	NC score	0.019407 (rank : 134)
Query Neighborhood Hits	197	Target Neighborhood Hits	1001	Shared Neighborhood Hits	54
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

MYH7_HUMAN
θ value	4.03905 (rank : 152)	NC score	0.013691 (rank : 169)
Query Neighborhood Hits	197	Target Neighborhood Hits	1559	Shared Neighborhood Hits	66
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

MYST2_HUMAN
θ value	4.03905 (rank : 153)	NC score	0.006081 (rank : 190)
Query Neighborhood Hits	197	Target Neighborhood Hits	88	Shared Neighborhood Hits	9
SwissProt Accessions	O95251	Gene names	MYST2, HBO1, HBOa
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST2 (EC 2.3.1.48) (MYST protein 2) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (Histone acetyltransferase binding to ORC1).

MYST2_MOUSE
θ value	4.03905 (rank : 154)	NC score	0.006078 (rank : 191)
Query Neighborhood Hits	197	Target Neighborhood Hits	87	Shared Neighborhood Hits	9
SwissProt Accessions	Q5SVQ0, Q5SVQ1, Q5SVQ2, Q5SVQ3, Q5SVQ7, Q6PGC6, Q80Y65	Gene names	Myst2, Hbo1
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST2 (EC 2.3.1.48) (MYST protein 2) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (Histone acetyltransferase binding to ORC1).

THUM2_MOUSE
θ value	4.03905 (rank : 155)	NC score	0.008540 (rank : 184)
Query Neighborhood Hits	197	Target Neighborhood Hits	56	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CZB3	Gene names	Thumpd2
Domain Architecture
Description	THUMP domain-containing protein 2.

CHD5_HUMAN
θ value	5.27518 (rank : 156)	NC score	0.035242 (rank : 101)
Query Neighborhood Hits	197	Target Neighborhood Hits	349	Shared Neighborhood Hits	42
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

CJ078_MOUSE
θ value	5.27518 (rank : 157)	NC score	0.014338 (rank : 165)
Query Neighborhood Hits	197	Target Neighborhood Hits	559	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

CKAP4_HUMAN
θ value	5.27518 (rank : 158)	NC score	0.016094 (rank : 149)
Query Neighborhood Hits	197	Target Neighborhood Hits	592	Shared Neighborhood Hits	39
SwissProt Accessions	Q07065, Q504S5, Q53ES6	Gene names	CKAP4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

DIAP2_HUMAN
θ value	5.27518 (rank : 159)	NC score	0.004990 (rank : 193)
Query Neighborhood Hits	197	Target Neighborhood Hits	342	Shared Neighborhood Hits	23
SwissProt Accessions	O60879, O60878, Q8WX06, Q8WX48, Q9UJL2	Gene names	DIAPH2, DIA
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2).

ICAL_HUMAN
θ value	5.27518 (rank : 160)	NC score	0.015719 (rank : 156)
Query Neighborhood Hits	197	Target Neighborhood Hits	275	Shared Neighborhood Hits	20
SwissProt Accessions	P20810, O95360, Q96D08, Q9H1Z5	Gene names	CAST
Domain Architecture
Description	Calpastatin (Calpain inhibitor) (Sperm BS-17 component).

ISY1_HUMAN
θ value	5.27518 (rank : 161)	NC score	0.023643 (rank : 116)
Query Neighborhood Hits	197	Target Neighborhood Hits	31	Shared Neighborhood Hits	9
SwissProt Accessions	Q9ULR0, Q96IL2, Q9BT05	Gene names	KIAA1160
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor ISY1 homolog.

ISY1_MOUSE
θ value	5.27518 (rank : 162)	NC score	0.024464 (rank : 114)
Query Neighborhood Hits	197	Target Neighborhood Hits	35	Shared Neighborhood Hits	9
SwissProt Accessions	Q69ZQ2, Q8VDX4, Q9D3E2	Gene names	Kiaa1160
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor ISY1 homolog.

KINH_MOUSE
θ value	5.27518 (rank : 163)	NC score	0.014884 (rank : 163)
Query Neighborhood Hits	197	Target Neighborhood Hits	1082	Shared Neighborhood Hits	64
SwissProt Accessions	Q61768, O08711, Q61580	Gene names	Kif5b, Khcs, Kns1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

LIPA2_MOUSE
θ value	5.27518 (rank : 164)	NC score	0.015951 (rank : 152)
Query Neighborhood Hits	197	Target Neighborhood Hits	1282	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

MOR2A_MOUSE
θ value	5.27518 (rank : 165)	NC score	0.004198 (rank : 194)
Query Neighborhood Hits	197	Target Neighborhood Hits	220	Shared Neighborhood Hits	13
SwissProt Accessions	Q69ZX6, Q5QNQ7, Q6P547	Gene names	Morc2a, Kiaa0852, Zcwcc1
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 2A (Zinc finger CW-type coiled-coil domain protein 1).

MYH8_HUMAN
θ value	5.27518 (rank : 166)	NC score	0.015087 (rank : 161)
Query Neighborhood Hits	197	Target Neighborhood Hits	1610	Shared Neighborhood Hits	70
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

RBBP6_HUMAN
θ value	5.27518 (rank : 167)	NC score	0.028391 (rank : 106)
Query Neighborhood Hits	197	Target Neighborhood Hits	1135	Shared Neighborhood Hits	52
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

SETD2_HUMAN
θ value	5.27518 (rank : 168)	NC score	0.009134 (rank : 183)
Query Neighborhood Hits	197	Target Neighborhood Hits	412	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SYCP1_MOUSE
θ value	5.27518 (rank : 169)	NC score	0.018998 (rank : 135)
Query Neighborhood Hits	197	Target Neighborhood Hits	1456	Shared Neighborhood Hits	70
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

TRIP4_HUMAN
θ value	5.27518 (rank : 170)	NC score	0.006411 (rank : 189)
Query Neighborhood Hits	197	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	Q15650, Q96ED7, Q9UKH0	Gene names	TRIP4
Domain Architecture
Description	Activating signal cointegrator 1 (ASC-1) (Thyroid receptor-interacting protein 4) (TRIP-4).

TXND2_MOUSE
θ value	5.27518 (rank : 171)	NC score	0.036967 (rank : 99)
Query Neighborhood Hits	197	Target Neighborhood Hits	828	Shared Neighborhood Hits	55
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

UBP8_MOUSE
θ value	5.27518 (rank : 172)	NC score	0.008196 (rank : 186)
Query Neighborhood Hits	197	Target Neighborhood Hits	362	Shared Neighborhood Hits	39
SwissProt Accessions	Q80U87, Q80YP2, Q8R0D3, Q9EQU1, Q9WVP5	Gene names	Usp8, Kiaa0055, Ubpy
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy).

WDR60_MOUSE
θ value	5.27518 (rank : 173)	NC score	0.016644 (rank : 146)
Query Neighborhood Hits	197	Target Neighborhood Hits	344	Shared Neighborhood Hits	41
SwissProt Accessions	Q8C761, Q3UNM4	Gene names	Wdr60
Domain Architecture	No domain graphic available
Description	WD repeat protein 60.

ZN510_HUMAN
θ value	5.27518 (rank : 174)	NC score	-0.007299 (rank : 204)
Query Neighborhood Hits	197	Target Neighborhood Hits	764	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y2H8	Gene names	ZNF510, KIAA0972
Domain Architecture
Description	Zinc finger protein 510.

AMOL1_HUMAN
θ value	6.88961 (rank : 175)	NC score	0.009168 (rank : 182)
Query Neighborhood Hits	197	Target Neighborhood Hits	435	Shared Neighborhood Hits	37
SwissProt Accessions	Q8IY63, Q63HK7, Q8NDN0, Q8WXD1, Q96CM5	Gene names	AMOTL1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

CDC37_HUMAN
θ value	6.88961 (rank : 176)	NC score	0.021380 (rank : 120)
Query Neighborhood Hits	197	Target Neighborhood Hits	506	Shared Neighborhood Hits	51
SwissProt Accessions	Q16543	Gene names	CDC37
Domain Architecture
Description	Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37).

CENPF_HUMAN
θ value	6.88961 (rank : 177)	NC score	0.012826 (rank : 172)
Query Neighborhood Hits	197	Target Neighborhood Hits	1932	Shared Neighborhood Hits	71
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

DYH5_MOUSE
θ value	6.88961 (rank : 178)	NC score	0.012151 (rank : 176)
Query Neighborhood Hits	197	Target Neighborhood Hits	286	Shared Neighborhood Hits	31
SwissProt Accessions	Q8VHE6, Q8BWG1	Gene names	Dnah5, Dnahc5
Domain Architecture	No domain graphic available
Description	Ciliary dynein heavy chain 5 (Axonemal beta dynein heavy chain 5) (Mdnah5).

FA44A_HUMAN
θ value	6.88961 (rank : 179)	NC score	0.018583 (rank : 139)
Query Neighborhood Hits	197	Target Neighborhood Hits	280	Shared Neighborhood Hits	34
SwissProt Accessions	Q8NFC6, Q6P0M8	Gene names	FAM44A
Domain Architecture	No domain graphic available
Description	Protein FAM44A.

FLIP1_HUMAN
θ value	6.88961 (rank : 180)	NC score	0.019537 (rank : 133)
Query Neighborhood Hits	197	Target Neighborhood Hits	1405	Shared Neighborhood Hits	67
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

MAP9_MOUSE
θ value	6.88961 (rank : 181)	NC score	0.016532 (rank : 147)
Query Neighborhood Hits	197	Target Neighborhood Hits	529	Shared Neighborhood Hits	52
SwissProt Accessions	Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7	Gene names	Map9, Asap
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

MY18A_HUMAN
θ value	6.88961 (rank : 182)	NC score	0.019948 (rank : 129)
Query Neighborhood Hits	197	Target Neighborhood Hits	1929	Shared Neighborhood Hits	84
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

NOTC2_MOUSE
θ value	6.88961 (rank : 183)	NC score	-0.005896 (rank : 201)
Query Neighborhood Hits	197	Target Neighborhood Hits	1069	Shared Neighborhood Hits	6
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

OPTN_HUMAN
θ value	6.88961 (rank : 184)	NC score	0.015358 (rank : 159)
Query Neighborhood Hits	197	Target Neighborhood Hits	827	Shared Neighborhood Hits	58
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

PARD3_HUMAN
θ value	6.88961 (rank : 185)	NC score	0.001248 (rank : 199)
Query Neighborhood Hits	197	Target Neighborhood Hits	312	Shared Neighborhood Hits	15
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

TACC3_MOUSE
θ value	6.88961 (rank : 186)	NC score	0.012189 (rank : 175)
Query Neighborhood Hits	197	Target Neighborhood Hits	607	Shared Neighborhood Hits	44
SwissProt Accessions	Q9JJ11, Q9WVK9	Gene names	Tacc3, Aint
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ARNT-interacting protein).

WAPL_HUMAN
θ value	6.88961 (rank : 187)	NC score	0.012618 (rank : 174)
Query Neighborhood Hits	197	Target Neighborhood Hits	122	Shared Neighborhood Hits	11
SwissProt Accessions	Q7Z5K2, Q5VSK5, Q8IX10, Q92549	Gene names	WAPAL, FOE, KIAA0261, WAPL
Domain Architecture	No domain graphic available
Description	Wings apart-like protein homolog (Friend of EBNA2 protein).

BAZ2B_HUMAN
θ value	8.99809 (rank : 188)	NC score	0.013695 (rank : 168)
Query Neighborhood Hits	197	Target Neighborhood Hits	803	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

CCD46_MOUSE
θ value	8.99809 (rank : 189)	NC score	0.015971 (rank : 151)
Query Neighborhood Hits	197	Target Neighborhood Hits	1405	Shared Neighborhood Hits	67
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

IF2P_HUMAN
θ value	8.99809 (rank : 190)	NC score	0.022204 (rank : 119)
Query Neighborhood Hits	197	Target Neighborhood Hits	889	Shared Neighborhood Hits	74
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

IWS1_MOUSE
θ value	8.99809 (rank : 191)	NC score	0.022506 (rank : 117)
Query Neighborhood Hits	197	Target Neighborhood Hits	1258	Shared Neighborhood Hits	50
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MATR3_MOUSE
θ value	8.99809 (rank : 192)	NC score	0.015609 (rank : 157)
Query Neighborhood Hits	197	Target Neighborhood Hits	321	Shared Neighborhood Hits	25
SwissProt Accessions	Q8K310	Gene names	Matr3
Domain Architecture	No domain graphic available
Description	Matrin-3.

MTSS1_HUMAN
θ value	8.99809 (rank : 193)	NC score	0.001666 (rank : 198)
Query Neighborhood Hits	197	Target Neighborhood Hits	504	Shared Neighborhood Hits	14
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

MYH3_HUMAN
θ value	8.99809 (rank : 194)	NC score	0.016670 (rank : 144)
Query Neighborhood Hits	197	Target Neighborhood Hits	1660	Shared Neighborhood Hits	72
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

PEG3_MOUSE
θ value	8.99809 (rank : 195)	NC score	-0.005087 (rank : 200)
Query Neighborhood Hits	197	Target Neighborhood Hits	1101	Shared Neighborhood Hits	24
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

PKHA6_MOUSE
θ value	8.99809 (rank : 196)	NC score	0.003124 (rank : 195)
Query Neighborhood Hits	197	Target Neighborhood Hits	591	Shared Neighborhood Hits	29
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

SH24A_MOUSE
θ value	8.99809 (rank : 197)	NC score	0.013147 (rank : 171)
Query Neighborhood Hits	197	Target Neighborhood Hits	326	Shared Neighborhood Hits	28
SwissProt Accessions	Q9D7V1	Gene names	Sh2d4a
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 4A.

CC026_HUMAN
θ value	θ > 10 (rank : 198)	NC score	0.158009 (rank : 88)
Query Neighborhood Hits	197	Target Neighborhood Hits	39	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BQ75	Gene names	C3orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26.

CC026_MOUSE
θ value	θ > 10 (rank : 199)	NC score	0.126989 (rank : 90)
Query Neighborhood Hits	197	Target Neighborhood Hits	38	Shared Neighborhood Hits	26
SwissProt Accessions	Q9CZT6, Q9CY77	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26 homolog.

DDX58_HUMAN
θ value	θ > 10 (rank : 200)	NC score	0.193102 (rank : 87)
Query Neighborhood Hits	197	Target Neighborhood Hits	105	Shared Neighborhood Hits	60
SwissProt Accessions	O95786, Q5HYE1, Q5VYT1, Q9NT04	Gene names	DDX58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

HELC1_HUMAN
θ value	θ > 10 (rank : 201)	NC score	0.100932 (rank : 91)
Query Neighborhood Hits	197	Target Neighborhood Hits	71	Shared Neighborhood Hits	35
SwissProt Accessions	Q8N3C0, O43738, Q9H1I9, Q9NTR0	Gene names	ASCC3, HELIC1
Domain Architecture	No domain graphic available
Description	Activating signal cointegrator 1 complex subunit 3 (EC 3.6.1.-) (ASC-1 complex subunit p200) (Trip4 complex subunit p200) (Helicase, ATP binding 1).

SMAL1_HUMAN
θ value	θ > 10 (rank : 202)	NC score	0.075496 (rank : 92)
Query Neighborhood Hits	197	Target Neighborhood Hits	174	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

SMAL1_MOUSE
θ value	θ > 10 (rank : 203)	NC score	0.051353 (rank : 95)
Query Neighborhood Hits	197	Target Neighborhood Hits	157	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

U520_HUMAN
θ value	θ > 10 (rank : 204)	NC score	0.132275 (rank : 89)
Query Neighborhood Hits	197	Target Neighborhood Hits	88	Shared Neighborhood Hits	43
SwissProt Accessions	O75643, O94884, Q6PX59, Q96IF2, Q9H7S0	Gene names	ASCC3L1, HELIC2, KIAA0788
Domain Architecture	No domain graphic available
Description	U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.1.-) (U5 snRNP-specific 200 kDa protein) (U5-200KD) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog).

Hits sorted by NC score

DDX27_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	197	Target Neighborhood Hits	197	Shared Neighborhood Hits	197
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX27_MOUSE
NC score	0.995483 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	197	Target Neighborhood Hits	174	Shared Neighborhood Hits	128
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX47_MOUSE
NC score	0.977661 (rank : 3)	θ value	6.31527e-70 (rank : 4)
Query Neighborhood Hits	197	Target Neighborhood Hits	97	Shared Neighborhood Hits	87
SwissProt Accessions	Q9CWX9	Gene names	Ddx47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX47_HUMAN
NC score	0.977536 (rank : 4)	θ value	1.35953e-72 (rank : 3)
Query Neighborhood Hits	197	Target Neighborhood Hits	97	Shared Neighborhood Hits	87
SwissProt Accessions	Q9H0S4, Q96GM0, Q96NV8	Gene names	DDX47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX49_MOUSE
NC score	0.975263 (rank : 5)	θ value	3.58603e-65 (rank : 6)
Query Neighborhood Hits	197	Target Neighborhood Hits	119	Shared Neighborhood Hits	87
SwissProt Accessions	Q4FZF3	Gene names	Ddx49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX49_HUMAN
NC score	0.972115 (rank : 6)	θ value	3.83135e-67 (rank : 5)
Query Neighborhood Hits	197	Target Neighborhood Hits	223	Shared Neighborhood Hits	99
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX52_HUMAN
NC score	0.964046 (rank : 7)	θ value	3.37202e-47 (rank : 39)
Query Neighborhood Hits	197	Target Neighborhood Hits	107	Shared Neighborhood Hits	88
SwissProt Accessions	Q9Y2R4, Q86YG1, Q8N213, Q9NVE0, Q9Y482	Gene names	DDX52, ROK1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX54_MOUSE
NC score	0.963870 (rank : 8)	θ value	7.24236e-58 (rank : 7)
Query Neighborhood Hits	197	Target Neighborhood Hits	124	Shared Neighborhood Hits	87
SwissProt Accessions	Q8K4L0	Gene names	Ddx54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54).

DDX52_MOUSE
NC score	0.963697 (rank : 9)	θ value	2.85459e-46 (rank : 40)
Query Neighborhood Hits	197	Target Neighborhood Hits	101	Shared Neighborhood Hits	88
SwissProt Accessions	Q8K301, Q8BV29	Gene names	Ddx52, Rok1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX6_HUMAN
NC score	0.962954 (rank : 10)	θ value	4.122e-45 (rank : 45)
Query Neighborhood Hits	197	Target Neighborhood Hits	97	Shared Neighborhood Hits	85
SwissProt Accessions	P26196	Gene names	DDX6, HLR2, RCK
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK).

DDX6_MOUSE
NC score	0.962717 (rank : 11)	θ value	4.122e-45 (rank : 46)
Query Neighborhood Hits	197	Target Neighborhood Hits	98	Shared Neighborhood Hits	85
SwissProt Accessions	P54823	Gene names	Ddx6, Hlr2, Rck
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK homolog).

DDX41_HUMAN
NC score	0.962549 (rank : 12)	θ value	2.58187e-47 (rank : 38)
Query Neighborhood Hits	197	Target Neighborhood Hits	111	Shared Neighborhood Hits	90
SwissProt Accessions	Q9UJV9, Q96BK6, Q96K05, Q9NT96, Q9NW04	Gene names	DDX41, ABS
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41) (DEAD box protein abstrakt homolog).

DDX41_MOUSE
NC score	0.962239 (rank : 13)	θ value	1.97686e-47 (rank : 37)
Query Neighborhood Hits	197	Target Neighborhood Hits	115	Shared Neighborhood Hits	90
SwissProt Accessions	Q91VN6	Gene names	Ddx41
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41).

DDX4_MOUSE
NC score	0.960679 (rank : 14)	θ value	2.41096e-53 (rank : 18)
Query Neighborhood Hits	197	Target Neighborhood Hits	100	Shared Neighborhood Hits	86
SwissProt Accessions	Q61496, Q9D5X7	Gene names	Ddx4, Vasa
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog) (Mvh).

DDX18_MOUSE
NC score	0.960235 (rank : 15)	θ value	1.97229e-55 (rank : 11)
Query Neighborhood Hits	197	Target Neighborhood Hits	115	Shared Neighborhood Hits	80
SwissProt Accessions	Q8K363, Q3MIB0, Q8BVZ2, Q9D2E0	Gene names	Ddx18
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18).

DDX54_HUMAN
NC score	0.960058 (rank : 16)	θ value	4.39379e-55 (rank : 13)
Query Neighborhood Hits	197	Target Neighborhood Hits	170	Shared Neighborhood Hits	89
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).

DDX4_HUMAN
NC score	0.959960 (rank : 17)	θ value	1.08223e-53 (rank : 17)
Query Neighborhood Hits	197	Target Neighborhood Hits	123	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NQI0, Q86VX0, Q9NT92, Q9NYB1	Gene names	DDX4, VASA
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog).

DDX48_HUMAN
NC score	0.959321 (rank : 18)	θ value	1.11993e-50 (rank : 21)
Query Neighborhood Hits	197	Target Neighborhood Hits	102	Shared Neighborhood Hits	86
SwissProt Accessions	P38919, Q15033, Q96A18	Gene names	DDX48, EIF4A3, KIAA0111
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Nuclear matrix protein 265) (hNMP 265) (Eukaryotic translation initiation factor 4A isoform 3).

DDX43_HUMAN
NC score	0.959219 (rank : 19)	θ value	6.58091e-43 (rank : 49)
Query Neighborhood Hits	197	Target Neighborhood Hits	120	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NXZ2, Q6NXR1	Gene names	DDX43, HAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.1.-) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen).

DDX48_MOUSE
NC score	0.959144 (rank : 20)	θ value	1.46268e-50 (rank : 22)
Query Neighborhood Hits	197	Target Neighborhood Hits	102	Shared Neighborhood Hits	86
SwissProt Accessions	Q91VC3	Gene names	Ddx48
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48).

DDX18_HUMAN
NC score	0.958064 (rank : 21)	θ value	6.56568e-51 (rank : 20)
Query Neighborhood Hits	197	Target Neighborhood Hits	124	Shared Neighborhood Hits	83
SwissProt Accessions	Q9NVP1, Q6IAU4, Q92732, Q9BQB7	Gene names	DDX18
Domain Architecture
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb).

DDX39_HUMAN
NC score	0.957854 (rank : 22)	θ value	4.70527e-49 (rank : 26)
Query Neighborhood Hits	197	Target Neighborhood Hits	94	Shared Neighborhood Hits	86
SwissProt Accessions	O00148, Q9BVP6, Q9H5W0	Gene names	DDX39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39) (Nuclear RNA helicase URH49).

IF4A1_HUMAN
NC score	0.957122 (rank : 23)	θ value	1.04822e-48 (rank : 27)
Query Neighborhood Hits	197	Target Neighborhood Hits	106	Shared Neighborhood Hits	86
SwissProt Accessions	P60842, P04765, Q5U018, Q61516	Gene names	EIF4A1, DDX2A, EIF4A
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A1_MOUSE
NC score	0.957122 (rank : 24)	θ value	1.04822e-48 (rank : 28)
Query Neighborhood Hits	197	Target Neighborhood Hits	106	Shared Neighborhood Hits	86
SwissProt Accessions	P60843, P04765, Q61516	Gene names	Eif4a1, Ddx2a, Eif4a
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

DDX39_MOUSE
NC score	0.956971 (rank : 25)	θ value	6.7944e-48 (rank : 32)
Query Neighborhood Hits	197	Target Neighborhood Hits	97	Shared Neighborhood Hits	85
SwissProt Accessions	Q8VDW0, Q3UJV4, Q8C2C2	Gene names	Ddx39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39).

DDX56_HUMAN
NC score	0.956880 (rank : 26)	θ value	2.04573e-44 (rank : 47)
Query Neighborhood Hits	197	Target Neighborhood Hits	77	Shared Neighborhood Hits	73
SwissProt Accessions	Q9NY93, Q9H9I8	Gene names	DDX56, DDX21, NOH61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD-box protein 21).

IF4A2_HUMAN
NC score	0.956811 (rank : 27)	θ value	1.788e-48 (rank : 29)
Query Neighborhood Hits	197	Target Neighborhood Hits	102	Shared Neighborhood Hits	86
SwissProt Accessions	Q14240, Q96B90, Q96EA8	Gene names	EIF4A2, DDX2B
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A2_MOUSE
NC score	0.956811 (rank : 28)	θ value	1.788e-48 (rank : 30)
Query Neighborhood Hits	197	Target Neighborhood Hits	102	Shared Neighborhood Hits	86
SwissProt Accessions	P10630, Q61513, Q61514	Gene names	Eif4a2, Ddx2b
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

DDX55_MOUSE
NC score	0.956752 (rank : 29)	θ value	1.3722e-40 (rank : 50)
Query Neighborhood Hits	197	Target Neighborhood Hits	111	Shared Neighborhood Hits	87
SwissProt Accessions	Q6ZPL9, Q149H5, Q3U460, Q8BZR1	Gene names	Ddx55, Kiaa1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX56_MOUSE
NC score	0.956506 (rank : 30)	θ value	3.15612e-45 (rank : 44)
Query Neighborhood Hits	197	Target Neighborhood Hits	87	Shared Neighborhood Hits	73
SwissProt Accessions	Q9D0R4	Gene names	Ddx56, D11Ertd619e, Noh61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase).

DDX17_MOUSE
NC score	0.956464 (rank : 31)	θ value	1.51363e-47 (rank : 35)
Query Neighborhood Hits	197	Target Neighborhood Hits	105	Shared Neighborhood Hits	87
SwissProt Accessions	Q501J6, Q6P5G1, Q8BIN2	Gene names	Ddx17
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17).

DDX17_HUMAN
NC score	0.956327 (rank : 32)	θ value	1.51363e-47 (rank : 34)
Query Neighborhood Hits	197	Target Neighborhood Hits	104	Shared Neighborhood Hits	87
SwissProt Accessions	Q92841, Q69YT1, Q6ICD6	Gene names	DDX17
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17) (RNA-dependent helicase p72) (DEAD box protein p72).

UAP56_HUMAN
NC score	0.956155 (rank : 33)	θ value	2.1121e-49 (rank : 24)
Query Neighborhood Hits	197	Target Neighborhood Hits	96	Shared Neighborhood Hits	85
SwissProt Accessions	Q13838, O43496, Q5RJ64, Q5RJ66, Q5ST94, Q5STB4, Q5STB5, Q5STB7, Q5STU4, Q5STU5, Q5STU6, Q5STU8, Q71V76	Gene names	BAT1, UAP56
Domain Architecture
Description	Spliceosome RNA helicase BAT1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (HLA-B-associated transcript-1).

UAP56_MOUSE
NC score	0.956131 (rank : 34)	θ value	2.1121e-49 (rank : 25)
Query Neighborhood Hits	197	Target Neighborhood Hits	96	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Z1N5, Q8HW97	Gene names	Bat1, Bat1a, Uap56
Domain Architecture	No domain graphic available
Description	Spliceosome RNA helicase Bat1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (HLA-B-associated transcript 1).

DDX10_HUMAN
NC score	0.955870 (rank : 35)	θ value	1.15626e-55 (rank : 10)
Query Neighborhood Hits	197	Target Neighborhood Hits	210	Shared Neighborhood Hits	100
SwissProt Accessions	Q13206, Q5BJD8	Gene names	DDX10
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX55_HUMAN
NC score	0.955415 (rank : 36)	θ value	1.98146e-39 (rank : 51)
Query Neighborhood Hits	197	Target Neighborhood Hits	122	Shared Neighborhood Hits	88
SwissProt Accessions	Q8NHQ9, Q658L6, Q9HCH7	Gene names	DDX55, KIAA1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX53_HUMAN
NC score	0.954869 (rank : 37)	θ value	9.48078e-50 (rank : 23)
Query Neighborhood Hits	197	Target Neighborhood Hits	124	Shared Neighborhood Hits	82
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

DDX10_MOUSE
NC score	0.954363 (rank : 38)	θ value	8.28633e-54 (rank : 16)
Query Neighborhood Hits	197	Target Neighborhood Hits	233	Shared Neighborhood Hits	96
SwissProt Accessions	Q80Y44	Gene names	Ddx10
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX31_HUMAN
NC score	0.953492 (rank : 39)	θ value	3.15612e-45 (rank : 43)
Query Neighborhood Hits	197	Target Neighborhood Hits	132	Shared Neighborhood Hits	85
SwissProt Accessions	Q9H8H2, Q5K6N2, Q5K6N3, Q5K6N4, Q5VZJ4, Q5VZJ9, Q96E91, Q96NY2, Q96SX5, Q9H5K6	Gene names	DDX31
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX31 (EC 3.6.1.-) (DEAD box protein 31) (Helicain).

PL10_MOUSE
NC score	0.952753 (rank : 40)	θ value	3.0428e-56 (rank : 8)
Query Neighborhood Hits	197	Target Neighborhood Hits	120	Shared Neighborhood Hits	90
SwissProt Accessions	P16381	Gene names	D1Pas1, Pl10
Domain Architecture
Description	Putative ATP-dependent RNA helicase Pl10 (EC 3.6.1.-).

DDX3X_HUMAN
NC score	0.952640 (rank : 41)	θ value	5.19021e-56 (rank : 9)
Query Neighborhood Hits	197	Target Neighborhood Hits	122	Shared Neighborhood Hits	90
SwissProt Accessions	O00571, O15536	Gene names	DDX3X, DBX, DDX3
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (Helicase-like protein 2) (HLP2) (DEAD box, X isoform).

DDX3Y_MOUSE
NC score	0.952260 (rank : 42)	θ value	1.19655e-52 (rank : 19)
Query Neighborhood Hits	197	Target Neighborhood Hits	126	Shared Neighborhood Hits	90
SwissProt Accessions	Q62095, Q9QWS9	Gene names	Ddx3y, D1Pas1-rs1, Dead2
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal) (DEAD-box RNA helicase DEAD2) (mDEAD2) (D1Pas1-related sequence 1).

DDX5_HUMAN
NC score	0.952150 (rank : 43)	θ value	2.3352e-48 (rank : 31)
Query Neighborhood Hits	197	Target Neighborhood Hits	102	Shared Neighborhood Hits	87
SwissProt Accessions	P17844, O75681	Gene names	DDX5, HELR, HLR1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68).

DDX3X_MOUSE
NC score	0.952090 (rank : 44)	θ value	4.39379e-55 (rank : 12)
Query Neighborhood Hits	197	Target Neighborhood Hits	117	Shared Neighborhood Hits	90
SwissProt Accessions	Q62167, O09060, O09143	Gene names	Ddx3x, D1Pas1-rs2, Ddx3, Dead3, Erh
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (DEAD box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1Pas1-related sequence 2).

DDX5_MOUSE
NC score	0.952012 (rank : 45)	θ value	6.7944e-48 (rank : 33)
Query Neighborhood Hits	197	Target Neighborhood Hits	101	Shared Neighborhood Hits	87
SwissProt Accessions	Q61656	Gene names	Ddx5, Tnz2
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68) (DEAD box RNA helicase DEAD1) (mDEAD1).

DDX3Y_HUMAN
NC score	0.951164 (rank : 46)	θ value	1.2784e-54 (rank : 14)
Query Neighborhood Hits	197	Target Neighborhood Hits	121	Shared Neighborhood Hits	90
SwissProt Accessions	O15523, Q8IYV7	Gene names	DDX3Y, DBY
Domain Architecture
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal).

DDX28_MOUSE
NC score	0.950838 (rank : 47)	θ value	1.98606e-31 (rank : 65)
Query Neighborhood Hits	197	Target Neighborhood Hits	112	Shared Neighborhood Hits	89
SwissProt Accessions	Q9CWT6, Q3TQM0	Gene names	Ddx28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX51_MOUSE
NC score	0.950033 (rank : 48)	θ value	1.51363e-47 (rank : 36)
Query Neighborhood Hits	197	Target Neighborhood Hits	130	Shared Neighborhood Hits	88
SwissProt Accessions	Q6P9R1, Q3U7M2	Gene names	Ddx51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX28_HUMAN
NC score	0.946277 (rank : 49)	θ value	5.40856e-29 (rank : 66)
Query Neighborhood Hits	197	Target Neighborhood Hits	103	Shared Neighborhood Hits	84
SwissProt Accessions	Q9NUL7	Gene names	DDX28, MDDX28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX46_HUMAN
NC score	0.943078 (rank : 50)	θ value	6.35935e-46 (rank : 41)
Query Neighborhood Hits	197	Target Neighborhood Hits	357	Shared Neighborhood Hits	124
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

DDX20_HUMAN
NC score	0.942180 (rank : 51)	θ value	1.28434e-38 (rank : 54)
Query Neighborhood Hits	197	Target Neighborhood Hits	121	Shared Neighborhood Hits	89
SwissProt Accessions	Q9UHI6, Q96F72, Q9NVM3, Q9UF59, Q9UIY0, Q9Y659	Gene names	DDX20, DP103, GEMIN3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3).

DDX50_HUMAN
NC score	0.941717 (rank : 52)	θ value	1.32909e-35 (rank : 60)
Query Neighborhood Hits	197	Target Neighborhood Hits	132	Shared Neighborhood Hits	89
SwissProt Accessions	Q9BQ39, Q8WV76, Q9BWI8	Gene names	DDX50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX50_MOUSE
NC score	0.941667 (rank : 53)	θ value	1.32909e-35 (rank : 61)
Query Neighborhood Hits	197	Target Neighborhood Hits	137	Shared Neighborhood Hits	89
SwissProt Accessions	Q99MJ9	Gene names	Ddx50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX23_HUMAN
NC score	0.941407 (rank : 54)	θ value	2.18062e-54 (rank : 15)
Query Neighborhood Hits	197	Target Neighborhood Hits	486	Shared Neighborhood Hits	132
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

DDX46_MOUSE
NC score	0.941084 (rank : 55)	θ value	6.35935e-46 (rank : 42)
Query Neighborhood Hits	197	Target Neighborhood Hits	358	Shared Neighborhood Hits	121
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

DDX20_MOUSE
NC score	0.938748 (rank : 56)	θ value	8.32485e-38 (rank : 57)
Query Neighborhood Hits	197	Target Neighborhood Hits	177	Shared Neighborhood Hits	91
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

DDX25_MOUSE
NC score	0.937611 (rank : 57)	θ value	7.52953e-39 (rank : 53)
Query Neighborhood Hits	197	Target Neighborhood Hits	98	Shared Neighborhood Hits	85
SwissProt Accessions	Q9QY15, Q8R1B6	Gene names	Ddx25, Grth
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX25_HUMAN
NC score	0.937444 (rank : 58)	θ value	1.20211e-36 (rank : 59)
Query Neighborhood Hits	197	Target Neighborhood Hits	93	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UHL0, Q86W81, Q8IYP1	Gene names	DDX25, GRTH
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DD19A_HUMAN
NC score	0.936558 (rank : 59)	θ value	4.88048e-38 (rank : 56)
Query Neighborhood Hits	197	Target Neighborhood Hits	107	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NUU7, Q53FM0	Gene names	DDX19A, DDX19L
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DDX19-like protein).

DD19A_MOUSE
NC score	0.936213 (rank : 60)	θ value	2.86122e-38 (rank : 55)
Query Neighborhood Hits	197	Target Neighborhood Hits	105	Shared Neighborhood Hits	89
SwissProt Accessions	Q61655, Q921R0	Gene names	Ddx19a, Ddx19, Eif4a-rs1
Domain Architecture
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DEAD box RNA helicase DEAD5) (mDEAD5) (Eukaryotic translation initiation factor 4A-related sequence 1).

DD19B_HUMAN
NC score	0.935995 (rank : 61)	θ value	2.58786e-39 (rank : 52)
Query Neighborhood Hits	197	Target Neighborhood Hits	109	Shared Neighborhood Hits	88
SwissProt Accessions	Q9UMR2, Q6FIB7, Q6IAE0	Gene names	DDX19B, DBP5, DDX19
Domain Architecture
Description	ATP-dependent RNA helicase DDX19B (EC 3.6.1.-) (DEAD box protein 19B) (DEAD box RNA helicase DEAD5).

DDX24_MOUSE
NC score	0.935638 (rank : 62)	θ value	8.06329e-33 (rank : 64)
Query Neighborhood Hits	197	Target Neighborhood Hits	147	Shared Neighborhood Hits	92
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX51_HUMAN
NC score	0.934128 (rank : 63)	θ value	5.95217e-44 (rank : 48)
Query Neighborhood Hits	197	Target Neighborhood Hits	332	Shared Neighborhood Hits	88
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX24_HUMAN
NC score	0.932956 (rank : 64)	θ value	6.17384e-33 (rank : 63)
Query Neighborhood Hits	197	Target Neighborhood Hits	190	Shared Neighborhood Hits	89
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX21_HUMAN
NC score	0.932895 (rank : 65)	θ value	1.73584e-35 (rank : 62)
Query Neighborhood Hits	197	Target Neighborhood Hits	308	Shared Neighborhood Hits	113
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX21_MOUSE
NC score	0.925635 (rank : 66)	θ value	1.85459e-37 (rank : 58)
Query Neighborhood Hits	197	Target Neighborhood Hits	350	Shared Neighborhood Hits	108
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX1_MOUSE
NC score	0.885935 (rank : 67)	θ value	7.56453e-23 (rank : 67)
Query Neighborhood Hits	197	Target Neighborhood Hits	112	Shared Neighborhood Hits	83
SwissProt Accessions	Q91VR5, Q3TU41	Gene names	Ddx1
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1).

DDX1_HUMAN
NC score	0.882894 (rank : 68)	θ value	9.87957e-23 (rank : 68)
Query Neighborhood Hits	197	Target Neighborhood Hits	110	Shared Neighborhood Hits	83
SwissProt Accessions	Q92499	Gene names	DDX1
Domain Architecture
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB).

RECQ4_HUMAN
NC score	0.554214 (rank : 69)	θ value	0.000158464 (rank : 79)
Query Neighborhood Hits	197	Target Neighborhood Hits	177	Shared Neighborhood Hits	85
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

RECQ4_MOUSE
NC score	0.536427 (rank : 70)	θ value	7.1131e-05 (rank : 76)
Query Neighborhood Hits	197	Target Neighborhood Hits	206	Shared Neighborhood Hits	85
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

BLM_MOUSE
NC score	0.496751 (rank : 71)	θ value	0.00869519 (rank : 85)
Query Neighborhood Hits	197	Target Neighborhood Hits	108	Shared Neighborhood Hits	72
SwissProt Accessions	O88700, O88198	Gene names	Blm
Domain Architecture
Description	Bloom syndrome protein homolog (EC 3.6.1.-) (mBLM).

RECQ5_HUMAN
NC score	0.482749 (rank : 72)	θ value	3.29651e-10 (rank : 69)
Query Neighborhood Hits	197	Target Neighborhood Hits	390	Shared Neighborhood Hits	80
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

BLM_HUMAN
NC score	0.482016 (rank : 73)	θ value	0.0193708 (rank : 87)
Query Neighborhood Hits	197	Target Neighborhood Hits	148	Shared Neighborhood Hits	77
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

WRN_HUMAN
NC score	0.474744 (rank : 74)	θ value	0.000461057 (rank : 81)
Query Neighborhood Hits	197	Target Neighborhood Hits	132	Shared Neighborhood Hits	83
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

FANCM_HUMAN
NC score	0.458660 (rank : 75)	θ value	3.41135e-07 (rank : 70)
Query Neighborhood Hits	197	Target Neighborhood Hits	210	Shared Neighborhood Hits	87
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

FANCM_MOUSE
NC score	0.453489 (rank : 76)	θ value	7.1131e-05 (rank : 75)
Query Neighborhood Hits	197	Target Neighborhood Hits	177	Shared Neighborhood Hits	84
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

WRN_MOUSE
NC score	0.445662 (rank : 77)	θ value	0.000158464 (rank : 80)
Query Neighborhood Hits	197	Target Neighborhood Hits	295	Shared Neighborhood Hits	95
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

RECQ1_HUMAN
NC score	0.444265 (rank : 78)	θ value	1.43324e-05 (rank : 71)
Query Neighborhood Hits	197	Target Neighborhood Hits	100	Shared Neighborhood Hits	73
SwissProt Accessions	P46063	Gene names	RECQL, RECQL1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

RECQ1_MOUSE
NC score	0.443646 (rank : 79)	θ value	4.1701e-05 (rank : 73)
Query Neighborhood Hits	197	Target Neighborhood Hits	95	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Z129, Q9Z128	Gene names	Recql, Recql1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

DICER_HUMAN
NC score	0.425719 (rank : 80)	θ value	0.000121331 (rank : 78)
Query Neighborhood Hits	197	Target Neighborhood Hits	126	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UPY3, O95943, Q9UQ02	Gene names	DICER1, DICER, HERNA, KIAA0928
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Helicase with RNase motif) (Helicase-MOI).

DICER_MOUSE
NC score	0.424975 (rank : 81)	θ value	7.1131e-05 (rank : 74)
Query Neighborhood Hits	197	Target Neighborhood Hits	140	Shared Neighborhood Hits	84
SwissProt Accessions	Q8R418	Gene names	Dicer1, Dicer, Mdcr
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Double-strand-specific ribonuclease mDCR-1).

LGP2_MOUSE
NC score	0.366860 (rank : 82)	θ value	2.44474e-05 (rank : 72)
Query Neighborhood Hits	197	Target Neighborhood Hits	86	Shared Neighborhood Hits	71
SwissProt Accessions	Q99J87, Q9D1X4	Gene names	Lgp2, D11lgp2e
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2).

IFIH1_HUMAN
NC score	0.356642 (rank : 83)	θ value	0.00665767 (rank : 84)
Query Neighborhood Hits	197	Target Neighborhood Hits	96	Shared Neighborhood Hits	76
SwissProt Accessions	Q9BYX4, Q6DC96, Q86X56, Q96MX8, Q9H3G6	Gene names	IFIH1, MDA5, RH116
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon-induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5) (RNA helicase-DEAD box protein 116) (Murabutide-down- regulated protein).

LGP2_HUMAN
NC score	0.352743 (rank : 84)	θ value	9.29e-05 (rank : 77)
Query Neighborhood Hits	197	Target Neighborhood Hits	94	Shared Neighborhood Hits	72
SwissProt Accessions	Q96C10, Q9HAM6	Gene names	LGP2, D11LGP2E
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2 homolog).

IFIH1_MOUSE
NC score	0.343121 (rank : 85)	θ value	0.00134147 (rank : 82)
Query Neighborhood Hits	197	Target Neighborhood Hits	126	Shared Neighborhood Hits	82
SwissProt Accessions	Q8R5F7, Q3U6S2, Q68EM4, Q8BYC9, Q8BZ01, Q8K5C7, Q8R144, Q8VE79, Q99KS4, Q9D2Z5	Gene names	Ifih1
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5).

DDX58_MOUSE
NC score	0.230132 (rank : 86)	θ value	0.0431538 (rank : 90)
Query Neighborhood Hits	197	Target Neighborhood Hits	99	Shared Neighborhood Hits	64
SwissProt Accessions	Q6Q899, Q8C320, Q8C5I3, Q8C7T2	Gene names	Ddx58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

DDX58_HUMAN
NC score	0.193102 (rank : 87)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	197	Target Neighborhood Hits	105	Shared Neighborhood Hits	60
SwissProt Accessions	O95786, Q5HYE1, Q5VYT1, Q9NT04	Gene names	DDX58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

CC026_HUMAN
NC score	0.158009 (rank : 88)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	197	Target Neighborhood Hits	39	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BQ75	Gene names	C3orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26.

U520_HUMAN
NC score	0.132275 (rank : 89)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	197	Target Neighborhood Hits	88	Shared Neighborhood Hits	43
SwissProt Accessions	O75643, O94884, Q6PX59, Q96IF2, Q9H7S0	Gene names	ASCC3L1, HELIC2, KIAA0788
Domain Architecture	No domain graphic available
Description	U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.1.-) (U5 snRNP-specific 200 kDa protein) (U5-200KD) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog).

CC026_MOUSE
NC score	0.126989 (rank : 90)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	197	Target Neighborhood Hits	38	Shared Neighborhood Hits	26
SwissProt Accessions	Q9CZT6, Q9CY77	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26 homolog.

HELC1_HUMAN
NC score	0.100932 (rank : 91)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	197	Target Neighborhood Hits	71	Shared Neighborhood Hits	35
SwissProt Accessions	Q8N3C0, O43738, Q9H1I9, Q9NTR0	Gene names	ASCC3, HELIC1
Domain Architecture	No domain graphic available
Description	Activating signal cointegrator 1 complex subunit 3 (EC 3.6.1.-) (ASC-1 complex subunit p200) (Trip4 complex subunit p200) (Helicase, ATP binding 1).

SMAL1_HUMAN
NC score	0.075496 (rank : 92)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	197	Target Neighborhood Hits	174	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

PHF20_MOUSE
NC score	0.060146 (rank : 93)	θ value	0.0148317 (rank : 86)
Query Neighborhood Hits	197	Target Neighborhood Hits	513	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

PHF20_HUMAN
NC score	0.052850 (rank : 94)	θ value	0.00509761 (rank : 83)
Query Neighborhood Hits	197	Target Neighborhood Hits	394	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

SMAL1_MOUSE
NC score	0.051353 (rank : 95)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	197	Target Neighborhood Hits	157	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

CHD4_HUMAN
NC score	0.045564 (rank : 96)	θ value	3.0926 (rank : 141)
Query Neighborhood Hits	197	Target Neighborhood Hits	365	Shared Neighborhood Hits	45
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD4_MOUSE
NC score	0.044968 (rank : 97)	θ value	3.0926 (rank : 142)
Query Neighborhood Hits	197	Target Neighborhood Hits	408	Shared Neighborhood Hits	41
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

CHD3_HUMAN
NC score	0.039929 (rank : 98)	θ value	0.47712 (rank : 107)
Query Neighborhood Hits	197	Target Neighborhood Hits	397	Shared Neighborhood Hits	37
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

TXND2_MOUSE
NC score	0.036967 (rank : 99)	θ value	5.27518 (rank : 171)
Query Neighborhood Hits	197	Target Neighborhood Hits	828	Shared Neighborhood Hits	55
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

CT2NL_HUMAN
NC score	0.036204 (rank : 100)	θ value	0.125558 (rank : 95)
Query Neighborhood Hits	197	Target Neighborhood Hits	1059	Shared Neighborhood Hits	61
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

CHD5_HUMAN
NC score	0.035242 (rank : 101)	θ value	5.27518 (rank : 156)
Query Neighborhood Hits	197	Target Neighborhood Hits	349	Shared Neighborhood Hits	42
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

LEO1_HUMAN
NC score	0.034333 (rank : 102)	θ value	1.06291 (rank : 122)
Query Neighborhood Hits	197	Target Neighborhood Hits	958	Shared Neighborhood Hits	56
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

CT2NL_MOUSE
NC score	0.033795 (rank : 103)	θ value	1.06291 (rank : 120)
Query Neighborhood Hits	197	Target Neighborhood Hits	902	Shared Neighborhood Hits	60
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

ATRX_HUMAN
NC score	0.029263 (rank : 104)	θ value	0.62314 (rank : 108)
Query Neighborhood Hits	197	Target Neighborhood Hits	842	Shared Neighborhood Hits	73
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

CYBP_HUMAN
NC score	0.029122 (rank : 105)	θ value	0.21417 (rank : 99)
Query Neighborhood Hits	197	Target Neighborhood Hits	23	Shared Neighborhood Hits	6
SwissProt Accessions	Q9HB71, O60666	Gene names	CACYBP, S100A6BP, SIP
Domain Architecture
Description	Calcyclin-binding protein (CacyBP) (hCacyBP) (Siah-interacting protein) (S100A6-binding protein).

RBBP6_HUMAN
NC score	0.028391 (rank : 106)	θ value	5.27518 (rank : 167)
Query Neighborhood Hits	197	Target Neighborhood Hits	1135	Shared Neighborhood Hits	52
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

TCAL5_HUMAN
NC score	0.028251 (rank : 107)	θ value	0.365318 (rank : 106)
Query Neighborhood Hits	197	Target Neighborhood Hits	806	Shared Neighborhood Hits	42
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

STMN1_MOUSE
NC score	0.027592 (rank : 108)	θ value	2.36792 (rank : 139)
Query Neighborhood Hits	197	Target Neighborhood Hits	560	Shared Neighborhood Hits	53
SwissProt Accessions	P54227	Gene names	Stmn1, Lag, Lap18, Pr22
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Pr22 protein) (Leukemia-associated gene protein).

TCAL3_HUMAN
NC score	0.027452 (rank : 109)	θ value	0.21417 (rank : 102)
Query Neighborhood Hits	197	Target Neighborhood Hits	274	Shared Neighborhood Hits	17
SwissProt Accessions	Q969E4	Gene names	TCEAL3
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 3 (TCEA-like protein 3) (Transcription elongation factor S-II protein-like 3).

STMN1_HUMAN
NC score	0.026280 (rank : 110)	θ value	3.0926 (rank : 145)
Query Neighborhood Hits	197	Target Neighborhood Hits	554	Shared Neighborhood Hits	51
SwissProt Accessions	P16949	Gene names	STMN1, LAP18, OP18
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Protein Pr22).

GOGA4_HUMAN
NC score	0.026172 (rank : 111)	θ value	0.62314 (rank : 110)
Query Neighborhood Hits	197	Target Neighborhood Hits	2034	Shared Neighborhood Hits	85
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

CCD41_MOUSE
NC score	0.024676 (rank : 112)	θ value	0.0431538 (rank : 89)
Query Neighborhood Hits	197	Target Neighborhood Hits	1399	Shared Neighborhood Hits	64
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

MAP1A_HUMAN
NC score	0.024526 (rank : 113)	θ value	0.813845 (rank : 114)
Query Neighborhood Hits	197	Target Neighborhood Hits	1626	Shared Neighborhood Hits	77
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

ISY1_MOUSE
NC score	0.024464 (rank : 114)	θ value	5.27518 (rank : 162)
Query Neighborhood Hits	197	Target Neighborhood Hits	35	Shared Neighborhood Hits	9
SwissProt Accessions	Q69ZQ2, Q8VDX4, Q9D3E2	Gene names	Kiaa1160
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor ISY1 homolog.

EPN4_MOUSE
NC score	0.023666 (rank : 115)	θ value	0.279714 (rank : 104)
Query Neighborhood Hits	197	Target Neighborhood Hits	58	Shared Neighborhood Hits	6
SwissProt Accessions	Q99KN9, Q8CFH4	Gene names	Clint1, Enth, Epn4, Epnr, Kiaa0171
Domain Architecture
Description	Clathrin interactor 1 (Epsin-4) (Epsin-related protein) (EpsinR) (Enthoprotin).

ISY1_HUMAN
NC score	0.023643 (rank : 116)	θ value	5.27518 (rank : 161)
Query Neighborhood Hits	197	Target Neighborhood Hits	31	Shared Neighborhood Hits	9
SwissProt Accessions	Q9ULR0, Q96IL2, Q9BT05	Gene names	KIAA1160
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor ISY1 homolog.

IWS1_MOUSE
NC score	0.022506 (rank : 117)	θ value	8.99809 (rank : 191)
Query Neighborhood Hits	197	Target Neighborhood Hits	1258	Shared Neighborhood Hits	50
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

SDPR_MOUSE
NC score	0.022385 (rank : 118)	θ value	1.81305 (rank : 134)
Query Neighborhood Hits	197	Target Neighborhood Hits	485	Shared Neighborhood Hits	42
SwissProt Accessions	Q63918, Q3V1P6, Q78EC3, Q8CBT4	Gene names	Sdpr, Sdr
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein).

IF2P_HUMAN
NC score	0.022204 (rank : 119)	θ value	8.99809 (rank : 190)
Query Neighborhood Hits	197	Target Neighborhood Hits	889	Shared Neighborhood Hits	74
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

CDC37_HUMAN
NC score	0.021380 (rank : 120)	θ value	6.88961 (rank : 176)
Query Neighborhood Hits	197	Target Neighborhood Hits	506	Shared Neighborhood Hits	51
SwissProt Accessions	Q16543	Gene names	CDC37
Domain Architecture
Description	Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37).

MD1L1_HUMAN
NC score	0.021374 (rank : 121)	θ value	0.21417 (rank : 100)
Query Neighborhood Hits	197	Target Neighborhood Hits	893	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

GOGA4_MOUSE
NC score	0.021323 (rank : 122)	θ value	0.0252991 (rank : 88)
Query Neighborhood Hits	197	Target Neighborhood Hits	1939	Shared Neighborhood Hits	76
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

EPN4_HUMAN
NC score	0.021237 (rank : 123)	θ value	0.62314 (rank : 109)
Query Neighborhood Hits	197	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	Q14677, Q8NAF1, Q96E05	Gene names	CLINT1, ENTH, EPN4, EPNR, KIAA0171
Domain Architecture
Description	Clathrin interactor 1 (Epsin-4) (Epsin-related protein) (EpsinR) (Enthoprotin) (Clathrin-interacting protein localized in the trans- Golgi region) (Clint).

CJ118_MOUSE
NC score	0.021106 (rank : 124)	θ value	0.21417 (rank : 98)
Query Neighborhood Hits	197	Target Neighborhood Hits	1132	Shared Neighborhood Hits	64
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

SAFB2_HUMAN
NC score	0.021095 (rank : 125)	θ value	2.36792 (rank : 138)
Query Neighborhood Hits	197	Target Neighborhood Hits	720	Shared Neighborhood Hits	54
SwissProt Accessions	Q14151, Q8TB13	Gene names	SAFB2, KIAA0138
Domain Architecture
Description	Scaffold attachment factor B2.

TRHY_HUMAN
NC score	0.020993 (rank : 126)	θ value	0.813845 (rank : 116)
Query Neighborhood Hits	197	Target Neighborhood Hits	1385	Shared Neighborhood Hits	72
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

KTN1_MOUSE
NC score	0.020540 (rank : 127)	θ value	0.125558 (rank : 96)
Query Neighborhood Hits	197	Target Neighborhood Hits	1324	Shared Neighborhood Hits	68
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

MYH9_MOUSE
NC score	0.019987 (rank : 128)	θ value	0.0431538 (rank : 91)
Query Neighborhood Hits	197	Target Neighborhood Hits	1829	Shared Neighborhood Hits	77
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MY18A_HUMAN
NC score	0.019948 (rank : 129)	θ value	6.88961 (rank : 182)
Query Neighborhood Hits	197	Target Neighborhood Hits	1929	Shared Neighborhood Hits	84
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

AZI1_HUMAN
NC score	0.019914 (rank : 130)	θ value	1.06291 (rank : 118)
Query Neighborhood Hits	197	Target Neighborhood Hits	1000	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

SM1L2_MOUSE
NC score	0.019906 (rank : 131)	θ value	0.21417 (rank : 101)
Query Neighborhood Hits	197	Target Neighborhood Hits	918	Shared Neighborhood Hits	55
SwissProt Accessions	Q920F6	Gene names	Smc1l2
Domain Architecture
Description	Structural maintenance of chromosomes 1-like 2 protein (SMC1beta protein).

CP250_HUMAN
NC score	0.019746 (rank : 132)	θ value	0.0961366 (rank : 93)
Query Neighborhood Hits	197	Target Neighborhood Hits	1805	Shared Neighborhood Hits	67
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

FLIP1_HUMAN
NC score	0.019537 (rank : 133)	θ value	6.88961 (rank : 180)
Query Neighborhood Hits	197	Target Neighborhood Hits	1405	Shared Neighborhood Hits	67
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

MD1L1_MOUSE
NC score	0.019407 (rank : 134)	θ value	4.03905 (rank : 151)
Query Neighborhood Hits	197	Target Neighborhood Hits	1001	Shared Neighborhood Hits	54
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

SYCP1_MOUSE
NC score	0.018998 (rank : 135)	θ value	5.27518 (rank : 169)
Query Neighborhood Hits	197	Target Neighborhood Hits	1456	Shared Neighborhood Hits	70
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

TUFT1_MOUSE
NC score	0.018979 (rank : 136)	θ value	1.81305 (rank : 135)
Query Neighborhood Hits	197	Target Neighborhood Hits	732	Shared Neighborhood Hits	51
SwissProt Accessions	O08970	Gene names	Tuft1
Domain Architecture
Description	Tuftelin.

SETX_HUMAN
NC score	0.018960 (rank : 137)	θ value	0.62314 (rank : 112)
Query Neighborhood Hits	197	Target Neighborhood Hits	368	Shared Neighborhood Hits	27
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

CING_HUMAN
NC score	0.018658 (rank : 138)	θ value	1.06291 (rank : 119)
Query Neighborhood Hits	197	Target Neighborhood Hits	1275	Shared Neighborhood Hits	61
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

FA44A_HUMAN
NC score	0.018583 (rank : 139)	θ value	6.88961 (rank : 179)
Query Neighborhood Hits	197	Target Neighborhood Hits	280	Shared Neighborhood Hits	34
SwissProt Accessions	Q8NFC6, Q6P0M8	Gene names	FAM44A
Domain Architecture	No domain graphic available
Description	Protein FAM44A.

MYH9_HUMAN
NC score	0.018447 (rank : 140)	θ value	0.0961366 (rank : 94)
Query Neighborhood Hits	197	Target Neighborhood Hits	1762	Shared Neighborhood Hits	77
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

HMMR_MOUSE
NC score	0.017947 (rank : 141)	θ value	1.38821 (rank : 128)
Query Neighborhood Hits	197	Target Neighborhood Hits	1178	Shared Neighborhood Hits	65
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

T3JAM_HUMAN
NC score	0.017527 (rank : 142)	θ value	1.06291 (rank : 126)
Query Neighborhood Hits	197	Target Neighborhood Hits	533	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Y228, Q2YDB5, Q4VY06, Q7Z706	Gene names	TRAF3IP3, T3JAM
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

NIN_MOUSE
NC score	0.016976 (rank : 143)	θ value	0.279714 (rank : 105)
Query Neighborhood Hits	197	Target Neighborhood Hits	1376	Shared Neighborhood Hits	57
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

MYH3_HUMAN
NC score	0.016670 (rank : 144)	θ value	8.99809 (rank : 194)
Query Neighborhood Hits	197	Target Neighborhood Hits	1660	Shared Neighborhood Hits	72
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

WAPL_MOUSE
NC score	0.016665 (rank : 145)	θ value	0.813845 (rank : 117)
Query Neighborhood Hits	197	Target Neighborhood Hits	158	Shared Neighborhood Hits	12
SwissProt Accessions	Q65Z40, Q6ZQE9	Gene names	Wapal, Kiaa0261, Wapl
Domain Architecture	No domain graphic available
Description	Wings apart-like protein homolog (Dioxin-inducible factor 2) (DIF-2).

WDR60_MOUSE
NC score	0.016644 (rank : 146)	θ value	5.27518 (rank : 173)
Query Neighborhood Hits	197	Target Neighborhood Hits	344	Shared Neighborhood Hits	41
SwissProt Accessions	Q8C761, Q3UNM4	Gene names	Wdr60
Domain Architecture	No domain graphic available
Description	WD repeat protein 60.

MAP9_MOUSE
NC score	0.016532 (rank : 147)	θ value	6.88961 (rank : 181)
Query Neighborhood Hits	197	Target Neighborhood Hits	529	Shared Neighborhood Hits	52
SwissProt Accessions	Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7	Gene names	Map9, Asap
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

REST_MOUSE
NC score	0.016430 (rank : 148)	θ value	1.81305 (rank : 133)
Query Neighborhood Hits	197	Target Neighborhood Hits	1506	Shared Neighborhood Hits	73
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

CKAP4_HUMAN
NC score	0.016094 (rank : 149)	θ value	5.27518 (rank : 158)
Query Neighborhood Hits	197	Target Neighborhood Hits	592	Shared Neighborhood Hits	39
SwissProt Accessions	Q07065, Q504S5, Q53ES6	Gene names	CKAP4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

GOGA6_HUMAN
NC score	0.016015 (rank : 150)	θ value	3.0926 (rank : 144)
Query Neighborhood Hits	197	Target Neighborhood Hits	1007	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

CCD46_MOUSE
NC score	0.015971 (rank : 151)	θ value	8.99809 (rank : 189)
Query Neighborhood Hits	197	Target Neighborhood Hits	1405	Shared Neighborhood Hits	67
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

LIPA2_MOUSE
NC score	0.015951 (rank : 152)	θ value	5.27518 (rank : 164)
Query Neighborhood Hits	197	Target Neighborhood Hits	1282	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

TRIPB_HUMAN
NC score	0.015837 (rank : 153)	θ value	2.36792 (rank : 140)
Query Neighborhood Hits	197	Target Neighborhood Hits	1587	Shared Neighborhood Hits	65
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

ERCC4_MOUSE
NC score	0.015831 (rank : 154)	θ value	3.0926 (rank : 143)
Query Neighborhood Hits	197	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QZD4, O54810, Q8R0I3	Gene names	Ercc4
Domain Architecture
Description	DNA repair endonuclease XPF (EC 3.1.-.-) (DNA excision repair protein ERCC-4).

KINH_HUMAN
NC score	0.015814 (rank : 155)	θ value	2.36792 (rank : 136)
Query Neighborhood Hits	197	Target Neighborhood Hits	1231	Shared Neighborhood Hits	67
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

ICAL_HUMAN
NC score	0.015719 (rank : 156)	θ value	5.27518 (rank : 160)
Query Neighborhood Hits	197	Target Neighborhood Hits	275	Shared Neighborhood Hits	20
SwissProt Accessions	P20810, O95360, Q96D08, Q9H1Z5	Gene names	CAST
Domain Architecture
Description	Calpastatin (Calpain inhibitor) (Sperm BS-17 component).

MATR3_MOUSE
NC score	0.015609 (rank : 157)	θ value	8.99809 (rank : 192)
Query Neighborhood Hits	197	Target Neighborhood Hits	321	Shared Neighborhood Hits	25
SwissProt Accessions	Q8K310	Gene names	Matr3
Domain Architecture	No domain graphic available
Description	Matrin-3.

NEST_HUMAN
NC score	0.015392 (rank : 158)	θ value	2.36792 (rank : 137)
Query Neighborhood Hits	197	Target Neighborhood Hits	1305	Shared Neighborhood Hits	60
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

OPTN_HUMAN
NC score	0.015358 (rank : 159)	θ value	6.88961 (rank : 184)
Query Neighborhood Hits	197	Target Neighborhood Hits	827	Shared Neighborhood Hits	58
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

CP135_HUMAN
NC score	0.015306 (rank : 160)	θ value	1.38821 (rank : 127)
Query Neighborhood Hits	197	Target Neighborhood Hits	1290	Shared Neighborhood Hits	63
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

MYH8_HUMAN
NC score	0.015087 (rank : 161)	θ value	5.27518 (rank : 166)
Query Neighborhood Hits	197	Target Neighborhood Hits	1610	Shared Neighborhood Hits	70
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

CA051_MOUSE
NC score	0.014989 (rank : 162)	θ value	4.03905 (rank : 148)
Query Neighborhood Hits	197	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q3TQ03, Q3U1B8	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf51 homolog.

KINH_MOUSE
NC score	0.014884 (rank : 163)	θ value	5.27518 (rank : 163)
Query Neighborhood Hits	197	Target Neighborhood Hits	1082	Shared Neighborhood Hits	64
SwissProt Accessions	Q61768, O08711, Q61580	Gene names	Kif5b, Khcs, Kns1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

F10A5_HUMAN
NC score	0.014598 (rank : 164)	θ value	1.81305 (rank : 131)
Query Neighborhood Hits	197	Target Neighborhood Hits	277	Shared Neighborhood Hits	20
SwissProt Accessions	Q8NFI4	Gene names	FAM10A5
Domain Architecture	No domain graphic available
Description	Protein FAM10A5.

CJ078_MOUSE
NC score	0.014338 (rank : 165)	θ value	5.27518 (rank : 157)
Query Neighborhood Hits	197	Target Neighborhood Hits	559	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

RPGR_HUMAN
NC score	0.014301 (rank : 166)	θ value	1.06291 (rank : 123)
Query Neighborhood Hits	197	Target Neighborhood Hits	279	Shared Neighborhood Hits	28
SwissProt Accessions	Q92834, O00702, O00737, Q8N5T6, Q93039, Q9HD29, Q9UMR1	Gene names	RPGR, RP3, XLRP3
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator.

KI21A_HUMAN
NC score	0.013948 (rank : 167)	θ value	1.06291 (rank : 121)
Query Neighborhood Hits	197	Target Neighborhood Hits	1543	Shared Neighborhood Hits	75
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

BAZ2B_HUMAN
NC score	0.013695 (rank : 168)	θ value	8.99809 (rank : 188)
Query Neighborhood Hits	197	Target Neighborhood Hits	803	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

MYH7_HUMAN
NC score	0.013691 (rank : 169)	θ value	4.03905 (rank : 152)
Query Neighborhood Hits	197	Target Neighborhood Hits	1559	Shared Neighborhood Hits	66
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

OVGP1_HUMAN
NC score	0.013484 (rank : 170)	θ value	0.62314 (rank : 111)
Query Neighborhood Hits	197	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	Q12889, Q15841	Gene names	OVGP1, MUC9, OGP
Domain Architecture
Description	Oviduct-specific glycoprotein precursor (Oviductal glycoprotein) (Oviductin) (Estrogen-dependent oviduct protein) (Mucin 9).

SH24A_MOUSE
NC score	0.013147 (rank : 171)	θ value	8.99809 (rank : 197)
Query Neighborhood Hits	197	Target Neighborhood Hits	326	Shared Neighborhood Hits	28
SwissProt Accessions	Q9D7V1	Gene names	Sh2d4a
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 4A.

CENPF_HUMAN
NC score	0.012826 (rank : 172)	θ value	6.88961 (rank : 177)
Query Neighborhood Hits	197	Target Neighborhood Hits	1932	Shared Neighborhood Hits	71
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

NFH_HUMAN
NC score	0.012653 (rank : 173)	θ value	0.163984 (rank : 97)
Query Neighborhood Hits	197	Target Neighborhood Hits	1242	Shared Neighborhood Hits	78
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

WAPL_HUMAN
NC score	0.012618 (rank : 174)	θ value	6.88961 (rank : 187)
Query Neighborhood Hits	197	Target Neighborhood Hits	122	Shared Neighborhood Hits	11
SwissProt Accessions	Q7Z5K2, Q5VSK5, Q8IX10, Q92549	Gene names	WAPAL, FOE, KIAA0261, WAPL
Domain Architecture	No domain graphic available
Description	Wings apart-like protein homolog (Friend of EBNA2 protein).

TACC3_MOUSE
NC score	0.012189 (rank : 175)	θ value	6.88961 (rank : 186)
Query Neighborhood Hits	197	Target Neighborhood Hits	607	Shared Neighborhood Hits	44
SwissProt Accessions	Q9JJ11, Q9WVK9	Gene names	Tacc3, Aint
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ARNT-interacting protein).

DYH5_MOUSE
NC score	0.012151 (rank : 176)	θ value	6.88961 (rank : 178)
Query Neighborhood Hits	197	Target Neighborhood Hits	286	Shared Neighborhood Hits	31
SwissProt Accessions	Q8VHE6, Q8BWG1	Gene names	Dnah5, Dnahc5
Domain Architecture	No domain graphic available
Description	Ciliary dynein heavy chain 5 (Axonemal beta dynein heavy chain 5) (Mdnah5).

RTN4_HUMAN
NC score	0.012062 (rank : 177)	θ value	1.06291 (rank : 124)
Query Neighborhood Hits	197	Target Neighborhood Hits	357	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

K0831_HUMAN
NC score	0.011957 (rank : 178)	θ value	4.03905 (rank : 150)
Query Neighborhood Hits	197	Target Neighborhood Hits	203	Shared Neighborhood Hits	27
SwissProt Accessions	Q6ZNE5, O94920	Gene names	KIAA0831
Domain Architecture	No domain graphic available
Description	Protein KIAA0831.

AP4E1_HUMAN
NC score	0.010794 (rank : 179)	θ value	0.279714 (rank : 103)
Query Neighborhood Hits	197	Target Neighborhood Hits	57	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPM8, Q9Y588	Gene names	AP4E1
Domain Architecture
Description	AP-4 complex subunit epsilon-1 (Adapter-related protein complex 4 epsilon-1 subunit) (Epsilon subunit of AP-4) (AP-4 adapter complex epsilon subunit).

MDM2_MOUSE
NC score	0.010554 (rank : 180)	θ value	1.38821 (rank : 129)
Query Neighborhood Hits	197	Target Neighborhood Hits	77	Shared Neighborhood Hits	4
SwissProt Accessions	P23804, Q61040, Q64330	Gene names	Mdm2
Domain Architecture
Description	Ubiquitin-protein ligase E3 Mdm2 (EC 6.3.2.-) (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein).

F10A1_HUMAN
NC score	0.010304 (rank : 181)	θ value	4.03905 (rank : 149)
Query Neighborhood Hits	197	Target Neighborhood Hits	312	Shared Neighborhood Hits	22
SwissProt Accessions	P50502, O14999	Gene names	ST13, FAM10A1, HIP, SNC6
Domain Architecture
Description	Hsc70-interacting protein (Hip) (Suppression of tumorigenicity protein 13) (Putative tumor suppressor ST13) (Protein FAM10A1) (Progesterone receptor-associated p48 protein) (NY-REN-33 antigen).

AMOL1_HUMAN
NC score	0.009168 (rank : 182)	θ value	6.88961 (rank : 175)
Query Neighborhood Hits	197	Target Neighborhood Hits	435	Shared Neighborhood Hits	37
SwissProt Accessions	Q8IY63, Q63HK7, Q8NDN0, Q8WXD1, Q96CM5	Gene names	AMOTL1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

SETD2_HUMAN
NC score	0.009134 (rank : 183)	θ value	5.27518 (rank : 168)
Query Neighborhood Hits	197	Target Neighborhood Hits	412	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

THUM2_MOUSE
NC score	0.008540 (rank : 184)	θ value	4.03905 (rank : 155)
Query Neighborhood Hits	197	Target Neighborhood Hits	56	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CZB3	Gene names	Thumpd2
Domain Architecture
Description	THUMP domain-containing protein 2.

ADA30_HUMAN
NC score	0.008531 (rank : 185)	θ value	0.0961366 (rank : 92)
Query Neighborhood Hits	197	Target Neighborhood Hits	391	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

UBP8_MOUSE
NC score	0.008196 (rank : 186)	θ value	5.27518 (rank : 172)
Query Neighborhood Hits	197	Target Neighborhood Hits	362	Shared Neighborhood Hits	39
SwissProt Accessions	Q80U87, Q80YP2, Q8R0D3, Q9EQU1, Q9WVP5	Gene names	Usp8, Kiaa0055, Ubpy
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy).

BCAS1_HUMAN
NC score	0.007755 (rank : 187)	θ value	4.03905 (rank : 147)
Query Neighborhood Hits	197	Target Neighborhood Hits	133	Shared Neighborhood Hits	7
SwissProt Accessions	O75363, Q68CZ3	Gene names	BCAS1, AIBC1, NABC1
Domain Architecture	No domain graphic available
Description	Breast carcinoma amplified sequence 1 (Novel amplified in breast cancer 1) (Amplified and overexpressed in breast cancer).

RBM28_MOUSE
NC score	0.006736 (rank : 188)	θ value	0.813845 (rank : 115)
Query Neighborhood Hits	197	Target Neighborhood Hits	368	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CGC6, Q8BG25, Q8VEJ8, Q9CS22, Q9CSE6	Gene names	Rbm28
Domain Architecture	No domain graphic available
Description	RNA-binding protein 28 (RNA-binding motif protein 28).

TRIP4_HUMAN
NC score	0.006411 (rank : 189)	θ value	5.27518 (rank : 170)
Query Neighborhood Hits	197	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	Q15650, Q96ED7, Q9UKH0	Gene names	TRIP4
Domain Architecture
Description	Activating signal cointegrator 1 (ASC-1) (Thyroid receptor-interacting protein 4) (TRIP-4).

MYST2_HUMAN
NC score	0.006081 (rank : 190)	θ value	4.03905 (rank : 153)
Query Neighborhood Hits	197	Target Neighborhood Hits	88	Shared Neighborhood Hits	9
SwissProt Accessions	O95251	Gene names	MYST2, HBO1, HBOa
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST2 (EC 2.3.1.48) (MYST protein 2) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (Histone acetyltransferase binding to ORC1).

MYST2_MOUSE
NC score	0.006078 (rank : 191)	θ value	4.03905 (rank : 154)
Query Neighborhood Hits	197	Target Neighborhood Hits	87	Shared Neighborhood Hits	9
SwissProt Accessions	Q5SVQ0, Q5SVQ1, Q5SVQ2, Q5SVQ3, Q5SVQ7, Q6PGC6, Q80Y65	Gene names	Myst2, Hbo1
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST2 (EC 2.3.1.48) (MYST protein 2) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (Histone acetyltransferase binding to ORC1).

HERC2_HUMAN
NC score	0.005125 (rank : 192)	θ value	1.81305 (rank : 132)
Query Neighborhood Hits	197	Target Neighborhood Hits	163	Shared Neighborhood Hits	7
SwissProt Accessions	O95714, Q86SV7, Q86SV8, Q86SV9, Q86YY3, Q86YY4, Q86YY5, Q86YY6, Q86YY7, Q86YY8, Q86YY9, Q86YZ0, Q86YZ1	Gene names	HERC2
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

DIAP2_HUMAN
NC score	0.004990 (rank : 193)	θ value	5.27518 (rank : 159)
Query Neighborhood Hits	197	Target Neighborhood Hits	342	Shared Neighborhood Hits	23
SwissProt Accessions	O60879, O60878, Q8WX06, Q8WX48, Q9UJL2	Gene names	DIAPH2, DIA
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2).

MOR2A_MOUSE
NC score	0.004198 (rank : 194)	θ value	5.27518 (rank : 165)
Query Neighborhood Hits	197	Target Neighborhood Hits	220	Shared Neighborhood Hits	13
SwissProt Accessions	Q69ZX6, Q5QNQ7, Q6P547	Gene names	Morc2a, Kiaa0852, Zcwcc1
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 2A (Zinc finger CW-type coiled-coil domain protein 1).

PKHA6_MOUSE
NC score	0.003124 (rank : 195)	θ value	8.99809 (rank : 196)
Query Neighborhood Hits	197	Target Neighborhood Hits	591	Shared Neighborhood Hits	29
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

STK10_MOUSE
NC score	0.002544 (rank : 196)	θ value	1.06291 (rank : 125)
Query Neighborhood Hits	197	Target Neighborhood Hits	2132	Shared Neighborhood Hits	76
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

BCAR1_HUMAN
NC score	0.001975 (rank : 197)	θ value	4.03905 (rank : 146)
Query Neighborhood Hits	197	Target Neighborhood Hits	554	Shared Neighborhood Hits	3
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

MTSS1_HUMAN
NC score	0.001666 (rank : 198)	θ value	8.99809 (rank : 193)
Query Neighborhood Hits	197	Target Neighborhood Hits	504	Shared Neighborhood Hits	14
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

PARD3_HUMAN
NC score	0.001248 (rank : 199)	θ value	6.88961 (rank : 185)
Query Neighborhood Hits	197	Target Neighborhood Hits	312	Shared Neighborhood Hits	15
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

PEG3_MOUSE
NC score	-0.005087 (rank : 200)	θ value	8.99809 (rank : 195)
Query Neighborhood Hits	197	Target Neighborhood Hits	1101	Shared Neighborhood Hits	24
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

NOTC2_MOUSE
NC score	-0.005896 (rank : 201)	θ value	6.88961 (rank : 183)
Query Neighborhood Hits	197	Target Neighborhood Hits	1069	Shared Neighborhood Hits	6
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

ZN181_HUMAN
NC score	-0.006539 (rank : 202)	θ value	0.62314 (rank : 113)
Query Neighborhood Hits	197	Target Neighborhood Hits	764	Shared Neighborhood Hits	5
SwissProt Accessions	Q2M3W8, Q49A75	Gene names	ZNF181
Domain Architecture	No domain graphic available
Description	Zinc finger protein 181 (HHZ181).

ZN302_HUMAN
NC score	-0.006593 (rank : 203)	θ value	1.38821 (rank : 130)
Query Neighborhood Hits	197	Target Neighborhood Hits	755	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NR11, Q9BZD8, Q9P0J4	Gene names	ZNF302, ZNF135L, ZNF140L
Domain Architecture
Description	Zinc finger protein 302 (ZNF135-like) (ZNF140-like).

ZN510_HUMAN
NC score	-0.007299 (rank : 204)	θ value	5.27518 (rank : 174)
Query Neighborhood Hits	197	Target Neighborhood Hits	764	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y2H8	Gene names	ZNF510, KIAA0972
Domain Architecture
Description	Zinc finger protein 510.