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Network neighborhood for query Sequence : RPGR_HUMAN

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RPGR_HUMAN
SwissProt Accessions	Q92834, O00702, O00737, Q8N5T6, Q93039, Q9HD29, Q9UMR1	Gene names	RPGR, RP3, XLRP3
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RPGR_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	279	Target Neighborhood Hits	279	Shared Neighborhood Hits	279
SwissProt Accessions	Q92834, O00702, O00737, Q8N5T6, Q93039, Q9HD29, Q9UMR1	Gene names	RPGR, RP3, XLRP3
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator.

RPGR_MOUSE
θ value	0 (rank : 2)	NC score	0.925702 (rank : 2)
Query Neighborhood Hits	279	Target Neighborhood Hits	281	Shared Neighborhood Hits	102
SwissProt Accessions	Q9R0X5, O88408, Q9CU92	Gene names	Rpgr
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator (mRpgr).

HERC3_HUMAN
θ value	1.16164e-39 (rank : 3)	NC score	0.592539 (rank : 15)
Query Neighborhood Hits	279	Target Neighborhood Hits	62	Shared Neighborhood Hits	30
SwissProt Accessions	Q15034	Gene names	HERC3, KIAA0032
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain protein 3.

RCBT2_HUMAN
θ value	4.57862e-28 (rank : 4)	NC score	0.677547 (rank : 11)
Query Neighborhood Hits	279	Target Neighborhood Hits	158	Shared Neighborhood Hits	28
SwissProt Accessions	O95199	Gene names	RCBTB2, CHC1L, RLG
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 2 (Regulator of chromosome condensation and BTB domain-containing protein 2) (Chromosome condensation 1-like) (CHC1-L) (RCC1-like G exchanging factor).

RCC1_HUMAN
θ value	7.80994e-28 (rank : 5)	NC score	0.805458 (rank : 3)
Query Neighborhood Hits	279	Target Neighborhood Hits	47	Shared Neighborhood Hits	37
SwissProt Accessions	P18754	Gene names	RCC1, CHC1
Domain Architecture
Description	Regulator of chromosome condensation (Chromosome condensation protein 1) (Cell cycle regulatory protein).

RCC1_MOUSE
θ value	7.80994e-28 (rank : 6)	NC score	0.801750 (rank : 5)
Query Neighborhood Hits	279	Target Neighborhood Hits	45	Shared Neighborhood Hits	37
SwissProt Accessions	Q8VE37, Q3UDB6	Gene names	Rcc1, Chc1
Domain Architecture	No domain graphic available
Description	Regulator of chromosome condensation (Chromosome condensation protein 1).

HERC2_HUMAN
θ value	1.73987e-27 (rank : 7)	NC score	0.575354 (rank : 16)
Query Neighborhood Hits	279	Target Neighborhood Hits	163	Shared Neighborhood Hits	35
SwissProt Accessions	O95714, Q86SV7, Q86SV8, Q86SV9, Q86YY3, Q86YY4, Q86YY5, Q86YY6, Q86YY7, Q86YY8, Q86YY9, Q86YZ0, Q86YZ1	Gene names	HERC2
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

RCBT1_MOUSE
θ value	2.96777e-27 (rank : 8)	NC score	0.649042 (rank : 14)
Query Neighborhood Hits	279	Target Neighborhood Hits	157	Shared Neighborhood Hits	28
SwissProt Accessions	Q6NXM2, Q8BTZ6, Q8BZV0	Gene names	Rcbtb1
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 1 (Regulator of chromosome condensation and BTB domain-containing protein 1).

RCBT2_MOUSE
θ value	2.96777e-27 (rank : 9)	NC score	0.671642 (rank : 12)
Query Neighborhood Hits	279	Target Neighborhood Hits	156	Shared Neighborhood Hits	28
SwissProt Accessions	Q99LJ7, Q3TUA3, Q8BMG2	Gene names	Rcbtb2, Chc1l
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 2 (Regulator of chromosome condensation and BTB domain-containing protein 2) (Chromosome condensation 1-like).

HERC5_HUMAN
θ value	5.06226e-27 (rank : 10)	NC score	0.571802 (rank : 17)
Query Neighborhood Hits	279	Target Neighborhood Hits	66	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UII4	Gene names	HERC5, CEB1, CEBP1
Domain Architecture
Description	HECT domain and RCC1-like domain-containing protein 5 (Cyclin-E- binding protein 1).

NEK9_HUMAN
θ value	6.61148e-27 (rank : 11)	NC score	0.207819 (rank : 26)
Query Neighborhood Hits	279	Target Neighborhood Hits	900	Shared Neighborhood Hits	39
SwissProt Accessions	Q8TD19, Q52LK6, Q8NCN0, Q8TCY4, Q9UPI4, Q9Y6S4, Q9Y6S5, Q9Y6S6	Gene names	NEK9, KIAA1995, NEK8, NERCC
Domain Architecture
Description	Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (NimA-related protein kinase 9) (Never in mitosis A-related kinase 9) (Nercc1 kinase) (NIMA-related kinase 8) (Nek8).

RCBT1_HUMAN
θ value	8.63488e-27 (rank : 12)	NC score	0.649906 (rank : 13)
Query Neighborhood Hits	279	Target Neighborhood Hits	158	Shared Neighborhood Hits	28
SwissProt Accessions	Q8NDN9, Q969U9	Gene names	RCBTB1, CLLD7, E4.5
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 1 (Regulator of chromosome condensation and BTB domain-containing protein 1) (Chronic lymphocytic leukemia deletion region gene 7 protein) (CLL deletion region gene 7 protein).

SRGEF_HUMAN
θ value	8.63488e-27 (rank : 13)	NC score	0.803164 (rank : 4)
Query Neighborhood Hits	279	Target Neighborhood Hits	33	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UGK8, Q9UGK9	Gene names	SERGEF, DELGEF, GNEFR
Domain Architecture	No domain graphic available
Description	Secretion-regulating guanine nucleotide exchange factor (Guanine nucleotide exchange factor-related protein) (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF).

HERC2_MOUSE
θ value	1.12775e-26 (rank : 14)	NC score	0.571323 (rank : 18)
Query Neighborhood Hits	279	Target Neighborhood Hits	167	Shared Neighborhood Hits	33
SwissProt Accessions	Q4U2R1, O88473, Q3TRJ8, Q3TS47, Q3TST2, Q3UFQ6, Q3URH7, Q5DU32, Q7TPR5, Q80VV7, Q9QYT1, Q9Z168, Q9Z171	Gene names	Herc2, jdf2, Kiaa0393, rjs
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

NEK9_MOUSE
θ value	1.12775e-26 (rank : 15)	NC score	0.210421 (rank : 25)
Query Neighborhood Hits	279	Target Neighborhood Hits	890	Shared Neighborhood Hits	41
SwissProt Accessions	Q8K1R7, Q8R3P1	Gene names	Nek9, Nercc
Domain Architecture
Description	Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (NimA-related protein kinase 9) (Never in mitosis A-related kinase 9).

NEK8_HUMAN
θ value	4.73814e-25 (rank : 16)	NC score	0.195659 (rank : 28)
Query Neighborhood Hits	279	Target Neighborhood Hits	872	Shared Neighborhood Hits	37
SwissProt Accessions	Q86SG6, Q2M1S6, Q8NDH1	Gene names	NEK8, JCK, NEK12A
Domain Architecture
Description	Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never in mitosis A-related kinase 8) (NimA-related protein kinase 8) (NIMA-related kinase 12a).

SRGEF_MOUSE
θ value	4.01107e-24 (rank : 17)	NC score	0.792832 (rank : 6)
Query Neighborhood Hits	279	Target Neighborhood Hits	37	Shared Neighborhood Hits	28
SwissProt Accessions	Q80YD6, Q9QXB7	Gene names	Sergef, Delgef, Gnefr
Domain Architecture	No domain graphic available
Description	Secretion-regulating guanine nucleotide exchange factor (Guanine nucleotide exchange factor-related protein) (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF).

NEK8_MOUSE
θ value	1.5242e-23 (rank : 18)	NC score	0.195900 (rank : 27)
Query Neighborhood Hits	279	Target Neighborhood Hits	872	Shared Neighborhood Hits	36
SwissProt Accessions	Q91ZR4, Q3U498, Q9D685	Gene names	Nek8, Jck
Domain Architecture
Description	Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never in mitosis A-related kinase 8) (NimA-related protein kinase 8).

RCC2_MOUSE
θ value	9.24701e-21 (rank : 19)	NC score	0.777138 (rank : 7)
Query Neighborhood Hits	279	Target Neighborhood Hits	37	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BK67, Q6ZPQ0	Gene names	Rcc2, Kiaa1470
Domain Architecture	No domain graphic available
Description	Protein RCC2.

RCC2_HUMAN
θ value	3.51386e-20 (rank : 20)	NC score	0.776427 (rank : 8)
Query Neighborhood Hits	279	Target Neighborhood Hits	36	Shared Neighborhood Hits	28
SwissProt Accessions	Q9P258, Q8IVL9, Q9BSN6, Q9NPV8	Gene names	RCC2, KIAA1470, TD60
Domain Architecture	No domain graphic available
Description	Protein RCC2 (Telophase disk protein of 60 kDa) (RCC1-like protein TD- 60).

WBS16_HUMAN
θ value	5.25075e-16 (rank : 21)	NC score	0.739293 (rank : 9)
Query Neighborhood Hits	279	Target Neighborhood Hits	29	Shared Neighborhood Hits	28
SwissProt Accessions	Q96I51, Q548B1, Q9H0G7	Gene names	WBSCR16
Domain Architecture	No domain graphic available
Description	Williams-Beuren syndrome chromosome region 16 protein (RCC1-like G exchanging factor-like protein).

WBS16_MOUSE
θ value	1.52774e-15 (rank : 22)	NC score	0.733682 (rank : 10)
Query Neighborhood Hits	279	Target Neighborhood Hits	31	Shared Neighborhood Hits	28
SwissProt Accessions	Q9CYF5	Gene names	Wbscr16
Domain Architecture	No domain graphic available
Description	Williams-Beuren syndrome chromosome region 16 protein homolog.

ALS2_MOUSE
θ value	3.18553e-13 (rank : 23)	NC score	0.526002 (rank : 20)
Query Neighborhood Hits	279	Target Neighborhood Hits	111	Shared Neighborhood Hits	28
SwissProt Accessions	Q920R0, Q8JZR1, Q9CXJ3	Gene names	Als2
Domain Architecture
Description	Alsin (Amyotrophic lateral sclerosis protein 2 homolog).

ALS2_HUMAN
θ value	5.43371e-13 (rank : 24)	NC score	0.526639 (rank : 19)
Query Neighborhood Hits	279	Target Neighborhood Hits	121	Shared Neighborhood Hits	31
SwissProt Accessions	Q96Q42, Q8N1E0, Q96PC4, Q96Q41, Q9H973, Q9HCK9	Gene names	ALS2, KIAA1563
Domain Architecture
Description	Alsin (Amyotrophic lateral sclerosis protein 2).

MYCB2_HUMAN
θ value	1.133e-10 (rank : 25)	NC score	0.435786 (rank : 21)
Query Neighborhood Hits	279	Target Neighborhood Hits	390	Shared Neighborhood Hits	53
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

MYCB2_MOUSE
θ value	1.133e-10 (rank : 26)	NC score	0.427870 (rank : 22)
Query Neighborhood Hits	279	Target Neighborhood Hits	307	Shared Neighborhood Hits	42
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

CYLC1_HUMAN
θ value	9.29e-05 (rank : 27)	NC score	0.144443 (rank : 37)
Query Neighborhood Hits	279	Target Neighborhood Hits	408	Shared Neighborhood Hits	74
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

NSBP1_HUMAN
θ value	0.000121331 (rank : 28)	NC score	0.153676 (rank : 34)
Query Neighborhood Hits	279	Target Neighborhood Hits	251	Shared Neighborhood Hits	59
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

GOGB1_HUMAN
θ value	0.000270298 (rank : 29)	NC score	0.078647 (rank : 107)
Query Neighborhood Hits	279	Target Neighborhood Hits	2297	Shared Neighborhood Hits	160
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

ANR11_HUMAN
θ value	0.000461057 (rank : 30)	NC score	0.068838 (rank : 140)
Query Neighborhood Hits	279	Target Neighborhood Hits	1289	Shared Neighborhood Hits	119
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

NFH_HUMAN
θ value	0.000461057 (rank : 31)	NC score	0.061464 (rank : 166)
Query Neighborhood Hits	279	Target Neighborhood Hits	1242	Shared Neighborhood Hits	108
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

NFM_MOUSE
θ value	0.000786445 (rank : 32)	NC score	0.066925 (rank : 143)
Query Neighborhood Hits	279	Target Neighborhood Hits	1159	Shared Neighborhood Hits	119
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

IWS1_HUMAN
θ value	0.00102713 (rank : 33)	NC score	0.160178 (rank : 32)
Query Neighborhood Hits	279	Target Neighborhood Hits	1241	Shared Neighborhood Hits	161
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

DMP1_MOUSE
θ value	0.00134147 (rank : 34)	NC score	0.150415 (rank : 36)
Query Neighborhood Hits	279	Target Neighborhood Hits	498	Shared Neighborhood Hits	90
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

CCD46_MOUSE
θ value	0.00228821 (rank : 35)	NC score	0.076413 (rank : 116)
Query Neighborhood Hits	279	Target Neighborhood Hits	1405	Shared Neighborhood Hits	130
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

DMP1_HUMAN
θ value	0.00298849 (rank : 36)	NC score	0.164356 (rank : 31)
Query Neighborhood Hits	279	Target Neighborhood Hits	491	Shared Neighborhood Hits	100
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

DSPP_MOUSE
θ value	0.00509761 (rank : 37)	NC score	0.128895 (rank : 40)
Query Neighborhood Hits	279	Target Neighborhood Hits	491	Shared Neighborhood Hits	77
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

SAS10_HUMAN
θ value	0.00509761 (rank : 38)	NC score	0.092512 (rank : 76)
Query Neighborhood Hits	279	Target Neighborhood Hits	102	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NQZ2, Q6FI82	Gene names	CRLZ1, SAS10
Domain Architecture	No domain graphic available
Description	Something about silencing protein 10 (Disrupter of silencing SAS10) (Charged amino acid-rich leucine zipper 1).

NUCL_HUMAN
θ value	0.00665767 (rank : 39)	NC score	0.048705 (rank : 270)
Query Neighborhood Hits	279	Target Neighborhood Hits	415	Shared Neighborhood Hits	34
SwissProt Accessions	P19338, Q53SK1, Q8NB06	Gene names	NCL
Domain Architecture
Description	Nucleolin (Protein C23).

DAXX_MOUSE
θ value	0.00869519 (rank : 40)	NC score	0.086427 (rank : 89)
Query Neighborhood Hits	279	Target Neighborhood Hits	173	Shared Neighborhood Hits	30
SwissProt Accessions	O35613, Q9QWT8, Q9QWV3	Gene names	Daxx
Domain Architecture
Description	Death domain-associated protein 6 (Daxx).

IFT74_MOUSE
θ value	0.00869519 (rank : 41)	NC score	0.066189 (rank : 144)
Query Neighborhood Hits	279	Target Neighborhood Hits	939	Shared Neighborhood Hits	79
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

LEO1_MOUSE
θ value	0.00869519 (rank : 42)	NC score	0.171230 (rank : 29)
Query Neighborhood Hits	279	Target Neighborhood Hits	946	Shared Neighborhood Hits	151
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

MINT_MOUSE
θ value	0.00869519 (rank : 43)	NC score	0.070294 (rank : 135)
Query Neighborhood Hits	279	Target Neighborhood Hits	1514	Shared Neighborhood Hits	94
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

SYCP1_MOUSE
θ value	0.00869519 (rank : 44)	NC score	0.072596 (rank : 123)
Query Neighborhood Hits	279	Target Neighborhood Hits	1456	Shared Neighborhood Hits	123
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

ATRX_HUMAN
θ value	0.0113563 (rank : 45)	NC score	0.104429 (rank : 58)
Query Neighborhood Hits	279	Target Neighborhood Hits	842	Shared Neighborhood Hits	127
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

CYLC2_HUMAN
θ value	0.0113563 (rank : 46)	NC score	0.126778 (rank : 41)
Query Neighborhood Hits	279	Target Neighborhood Hits	223	Shared Neighborhood Hits	48
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

FBX24_MOUSE
θ value	0.0113563 (rank : 47)	NC score	0.281580 (rank : 24)
Query Neighborhood Hits	279	Target Neighborhood Hits	59	Shared Neighborhood Hits	28
SwissProt Accessions	Q9D417	Gene names	Fbxo24, Fbx24
Domain Architecture	No domain graphic available
Description	F-box only protein 24.

YTDC1_HUMAN
θ value	0.0113563 (rank : 48)	NC score	0.110351 (rank : 56)
Query Neighborhood Hits	279	Target Neighborhood Hits	458	Shared Neighborhood Hits	81
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

ARS2_HUMAN
θ value	0.0193708 (rank : 49)	NC score	0.096862 (rank : 68)
Query Neighborhood Hits	279	Target Neighborhood Hits	186	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BXP5, O95808, Q9BWP6, Q9BXP4	Gene names	ARS2, ASR2
Domain Architecture
Description	Arsenite-resistance protein 2.

ATRX_MOUSE
θ value	0.0193708 (rank : 50)	NC score	0.096819 (rank : 69)
Query Neighborhood Hits	279	Target Neighborhood Hits	682	Shared Neighborhood Hits	107
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

DSPP_HUMAN
θ value	0.0193708 (rank : 51)	NC score	0.136631 (rank : 38)
Query Neighborhood Hits	279	Target Neighborhood Hits	645	Shared Neighborhood Hits	98
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

FBX24_HUMAN
θ value	0.0193708 (rank : 52)	NC score	0.311713 (rank : 23)
Query Neighborhood Hits	279	Target Neighborhood Hits	57	Shared Neighborhood Hits	28
SwissProt Accessions	O75426, Q9H0G1	Gene names	FBXO24, FBX24
Domain Architecture
Description	F-box only protein 24.

MDN1_HUMAN
θ value	0.0193708 (rank : 53)	NC score	0.118063 (rank : 48)
Query Neighborhood Hits	279	Target Neighborhood Hits	662	Shared Neighborhood Hits	114
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

ANK2_HUMAN
θ value	0.0252991 (rank : 54)	NC score	0.037155 (rank : 312)
Query Neighborhood Hits	279	Target Neighborhood Hits	1615	Shared Neighborhood Hits	114
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

HUWE1_HUMAN
θ value	0.0252991 (rank : 55)	NC score	0.119948 (rank : 44)
Query Neighborhood Hits	279	Target Neighborhood Hits	443	Shared Neighborhood Hits	43
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

HUWE1_MOUSE
θ value	0.0252991 (rank : 56)	NC score	0.119478 (rank : 47)
Query Neighborhood Hits	279	Target Neighborhood Hits	406	Shared Neighborhood Hits	38
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

CALD1_HUMAN
θ value	0.0330416 (rank : 57)	NC score	0.080454 (rank : 105)
Query Neighborhood Hits	279	Target Neighborhood Hits	959	Shared Neighborhood Hits	91
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

KMHN1_HUMAN
θ value	0.0330416 (rank : 58)	NC score	0.068252 (rank : 141)
Query Neighborhood Hits	279	Target Neighborhood Hits	950	Shared Neighborhood Hits	93
SwissProt Accessions	Q8TBZ0, Q86YI9, Q8N7W0	Gene names	KMHN1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1.

MAP1B_HUMAN
θ value	0.0330416 (rank : 59)	NC score	0.112298 (rank : 53)
Query Neighborhood Hits	279	Target Neighborhood Hits	903	Shared Neighborhood Hits	108
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

NSBP1_MOUSE
θ value	0.0330416 (rank : 60)	NC score	0.157807 (rank : 33)
Query Neighborhood Hits	279	Target Neighborhood Hits	681	Shared Neighborhood Hits	127
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

PCLO_MOUSE
θ value	0.0330416 (rank : 61)	NC score	0.042542 (rank : 296)
Query Neighborhood Hits	279	Target Neighborhood Hits	2275	Shared Neighborhood Hits	105
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

SIAL_HUMAN
θ value	0.0330416 (rank : 62)	NC score	0.077735 (rank : 112)
Query Neighborhood Hits	279	Target Neighborhood Hits	77	Shared Neighborhood Hits	20
SwissProt Accessions	P21815	Gene names	IBSP, BNSP
Domain Architecture
Description	Bone sialoprotein-2 precursor (Bone sialoprotein II) (BSP II) (Cell- binding sialoprotein) (Integrin-binding sialoprotein).

DDX21_MOUSE
θ value	0.0431538 (rank : 63)	NC score	0.027031 (rank : 333)
Query Neighborhood Hits	279	Target Neighborhood Hits	350	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

ARS2_MOUSE
θ value	0.0563607 (rank : 64)	NC score	0.088297 (rank : 86)
Query Neighborhood Hits	279	Target Neighborhood Hits	212	Shared Neighborhood Hits	34
SwissProt Accessions	Q99MR6, Q99MR4, Q99MR5, Q99MR7	Gene names	Ars2, Asr2
Domain Architecture
Description	Arsenite-resistance protein 2.

CCAR1_HUMAN
θ value	0.0563607 (rank : 65)	NC score	0.090181 (rank : 80)
Query Neighborhood Hits	279	Target Neighborhood Hits	444	Shared Neighborhood Hits	72
SwissProt Accessions	Q8IX12, Q32NE3, Q5VUP6, Q6PIZ0, Q6X935, Q9H8N4, Q9NVA7, Q9NVQ0, Q9NWM6	Gene names	CCAR1, CARP1, DIS
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1) (Death inducer with SAP domain).

FA50A_MOUSE
θ value	0.0563607 (rank : 66)	NC score	0.062127 (rank : 161)
Query Neighborhood Hits	279	Target Neighborhood Hits	293	Shared Neighborhood Hits	39
SwissProt Accessions	Q9WV03, Q9D866	Gene names	Fam50a, D0HXS9928E, Xap5
Domain Architecture
Description	Protein FAM50A (XAP-5 protein).

RP1L1_HUMAN
θ value	0.0563607 (rank : 67)	NC score	0.074550 (rank : 120)
Query Neighborhood Hits	279	Target Neighborhood Hits	1072	Shared Neighborhood Hits	80
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

HTSF1_MOUSE
θ value	0.0736092 (rank : 68)	NC score	0.123393 (rank : 42)
Query Neighborhood Hits	279	Target Neighborhood Hits	425	Shared Neighborhood Hits	66
SwissProt Accessions	Q8BGC0, Q1WWK0, Q9CT41, Q9DAU3	Gene names	Htatsf1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 homolog.

MAP2_HUMAN
θ value	0.0736092 (rank : 69)	NC score	0.056700 (rank : 193)
Query Neighborhood Hits	279	Target Neighborhood Hits	348	Shared Neighborhood Hits	49
SwissProt Accessions	P11137, Q99975, Q99976	Gene names	MAP2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2) (MAP-2).

MYST3_HUMAN
θ value	0.0736092 (rank : 70)	NC score	0.063310 (rank : 158)
Query Neighborhood Hits	279	Target Neighborhood Hits	772	Shared Neighborhood Hits	85
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

NFM_HUMAN
θ value	0.0736092 (rank : 71)	NC score	0.061006 (rank : 168)
Query Neighborhood Hits	279	Target Neighborhood Hits	1328	Shared Neighborhood Hits	127
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

TRDN_HUMAN
θ value	0.0736092 (rank : 72)	NC score	0.088134 (rank : 87)
Query Neighborhood Hits	279	Target Neighborhood Hits	542	Shared Neighborhood Hits	72
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

CCAR1_MOUSE
θ value	0.0961366 (rank : 73)	NC score	0.099886 (rank : 64)
Query Neighborhood Hits	279	Target Neighborhood Hits	414	Shared Neighborhood Hits	67
SwissProt Accessions	Q8CH18, Q6AXC9, Q6PAR2, Q80XE4, Q8BJY0, Q8BVN2, Q8CGG1, Q9CSR5	Gene names	Ccar1, Carp1
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1).

IFT81_MOUSE
θ value	0.0961366 (rank : 74)	NC score	0.061909 (rank : 164)
Query Neighborhood Hits	279	Target Neighborhood Hits	959	Shared Neighborhood Hits	84
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

NALP5_MOUSE
θ value	0.0961366 (rank : 75)	NC score	0.070344 (rank : 134)
Query Neighborhood Hits	279	Target Neighborhood Hits	560	Shared Neighborhood Hits	116
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

AP3B1_MOUSE
θ value	0.125558 (rank : 76)	NC score	0.065734 (rank : 149)
Query Neighborhood Hits	279	Target Neighborhood Hits	302	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Z1T1, Q91YR4	Gene names	Ap3b1
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

CENPE_HUMAN
θ value	0.125558 (rank : 77)	NC score	0.059586 (rank : 176)
Query Neighborhood Hits	279	Target Neighborhood Hits	2060	Shared Neighborhood Hits	136
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

KNTC2_HUMAN
θ value	0.125558 (rank : 78)	NC score	0.059691 (rank : 175)
Query Neighborhood Hits	279	Target Neighborhood Hits	673	Shared Neighborhood Hits	55
SwissProt Accessions	O14777, Q6PJX2	Gene names	KNTC2, HEC, HEC1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (HsHec1) (Kinetochore-associated protein 2) (Highly expressed in cancer protein) (Retinoblastoma-associated protein HEC).

MY18A_HUMAN
θ value	0.125558 (rank : 79)	NC score	0.056246 (rank : 197)
Query Neighborhood Hits	279	Target Neighborhood Hits	1929	Shared Neighborhood Hits	152
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

NUF2_HUMAN
θ value	0.125558 (rank : 80)	NC score	0.066153 (rank : 145)
Query Neighborhood Hits	279	Target Neighborhood Hits	661	Shared Neighborhood Hits	67
SwissProt Accessions	Q9BZD4, Q8WU69, Q96HJ4, Q96Q78	Gene names	CDCA1, NUF2, NUF2R
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (hNuf2) (hNuf2R) (hsNuf2) (Cell division cycle-associated protein 1).

REST_HUMAN
θ value	0.125558 (rank : 81)	NC score	0.062017 (rank : 163)
Query Neighborhood Hits	279	Target Neighborhood Hits	1605	Shared Neighborhood Hits	128
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

OXR1_HUMAN
θ value	0.163984 (rank : 82)	NC score	0.083614 (rank : 101)
Query Neighborhood Hits	279	Target Neighborhood Hits	282	Shared Neighborhood Hits	72
SwissProt Accessions	Q8N573, Q3LIB5, Q6ZVK9, Q8N8V0, Q9H266, Q9NWC7	Gene names	OXR1
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1.

SAS10_MOUSE
θ value	0.163984 (rank : 83)	NC score	0.078341 (rank : 108)
Query Neighborhood Hits	279	Target Neighborhood Hits	81	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JI13, Q3UL95, Q8R5C6, Q9JJ12	Gene names	Crlz1, Crl1, Sas10
Domain Architecture	No domain graphic available
Description	Something about silencing protein 10 (Disrupter of silencing SAS10) (Charged amino acid-rich leucine zipper 1) (Crl-1).

T2FA_HUMAN
θ value	0.163984 (rank : 84)	NC score	0.091252 (rank : 77)
Query Neighborhood Hits	279	Target Neighborhood Hits	228	Shared Neighborhood Hits	48
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

TXD13_MOUSE
θ value	0.163984 (rank : 85)	NC score	0.050258 (rank : 260)
Query Neighborhood Hits	279	Target Neighborhood Hits	61	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C0L0, Q3UHC6, Q6ZPW7, Q80X49	Gene names	Txndc13, D2Bwg1356e, Kiaa1162
Domain Architecture
Description	Thioredoxin domain-containing protein 13 precursor.

IWS1_MOUSE
θ value	0.21417 (rank : 86)	NC score	0.150702 (rank : 35)
Query Neighborhood Hits	279	Target Neighborhood Hits	1258	Shared Neighborhood Hits	153
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

LYRIC_MOUSE
θ value	0.21417 (rank : 87)	NC score	0.063602 (rank : 157)
Query Neighborhood Hits	279	Target Neighborhood Hits	126	Shared Neighborhood Hits	21
SwissProt Accessions	Q80WJ7, Q3U9F8, Q3UAQ8, Q8BN67, Q8CBT9, Q8CDL0, Q8CGI7, Q9D052	Gene names	Mtdh, Lyric
Domain Architecture	No domain graphic available
Description	Protein LYRIC (Lysine-rich CEACAM1 co-isolated protein) (3D3/LYRIC) (Metastasis adhesion protein) (Metadherin).

MAP1B_MOUSE
θ value	0.21417 (rank : 88)	NC score	0.101167 (rank : 61)
Query Neighborhood Hits	279	Target Neighborhood Hits	977	Shared Neighborhood Hits	116
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

MPP10_HUMAN
θ value	0.21417 (rank : 89)	NC score	0.089332 (rank : 82)
Query Neighborhood Hits	279	Target Neighborhood Hits	306	Shared Neighborhood Hits	60
SwissProt Accessions	O00566	Gene names	MPHOSPH10, MPP10
Domain Architecture
Description	U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10).

AN32B_MOUSE
θ value	0.279714 (rank : 90)	NC score	0.054664 (rank : 212)
Query Neighborhood Hits	279	Target Neighborhood Hits	236	Shared Neighborhood Hits	29
SwissProt Accessions	Q9EST5	Gene names	Anp32b, Pal31
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member B (Proliferation-related acidic leucine-rich protein PAL31).

CLSPN_HUMAN
θ value	0.279714 (rank : 91)	NC score	0.085793 (rank : 91)
Query Neighborhood Hits	279	Target Neighborhood Hits	433	Shared Neighborhood Hits	82
SwissProt Accessions	Q9HAW4, Q5VYG0, Q6P6H5, Q8IWI1	Gene names	CLSPN
Domain Architecture	No domain graphic available
Description	Claspin (hClaspin) (Hu-Claspin).

HTSF1_HUMAN
θ value	0.279714 (rank : 92)	NC score	0.100814 (rank : 63)
Query Neighborhood Hits	279	Target Neighborhood Hits	408	Shared Neighborhood Hits	63
SwissProt Accessions	O43719, Q59G06, Q99730	Gene names	HTATSF1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 (Tat-SF1).

MYT1L_MOUSE
θ value	0.279714 (rank : 93)	NC score	0.060995 (rank : 169)
Query Neighborhood Hits	279	Target Neighborhood Hits	461	Shared Neighborhood Hits	68
SwissProt Accessions	P97500, O08996, Q8C643, Q8C7L4, Q8CHB4	Gene names	Myt1l, Kiaa1106, Nzf1, Png1
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (Postmitotic neural gene 1 protein) (Zinc finger protein Png-1) (Neural zinc finger factor 1) (NZF-1).

FA50A_HUMAN
θ value	0.365318 (rank : 94)	NC score	0.056252 (rank : 196)
Query Neighborhood Hits	279	Target Neighborhood Hits	264	Shared Neighborhood Hits	38
SwissProt Accessions	Q14320, Q5HY37	Gene names	FAM50A, DXS9928E, HXC26, XAP5
Domain Architecture
Description	Protein FAM50A (Protein XAP-5) (Protein HXC-26).

GON4L_HUMAN
θ value	0.365318 (rank : 95)	NC score	0.060989 (rank : 170)
Query Neighborhood Hits	279	Target Neighborhood Hits	555	Shared Neighborhood Hits	71
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

KNTC2_MOUSE
θ value	0.365318 (rank : 96)	NC score	0.058230 (rank : 179)
Query Neighborhood Hits	279	Target Neighborhood Hits	692	Shared Neighborhood Hits	53
SwissProt Accessions	Q9D0F1, Q3TQT6, Q3UWM5, Q99P70	Gene names	Kntc2, Hec1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (Kinetochore-associated protein 2).

LEO1_HUMAN
θ value	0.365318 (rank : 97)	NC score	0.165905 (rank : 30)
Query Neighborhood Hits	279	Target Neighborhood Hits	958	Shared Neighborhood Hits	150
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

SMCE1_MOUSE
θ value	0.365318 (rank : 98)	NC score	0.071257 (rank : 130)
Query Neighborhood Hits	279	Target Neighborhood Hits	409	Shared Neighborhood Hits	84
SwissProt Accessions	O54941, Q8BPD9	Gene names	Smarce1, Baf57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator chromatin subfamily E member 1 (BRG1-associated factor 57).

ABTAP_MOUSE
θ value	0.47712 (rank : 99)	NC score	0.089652 (rank : 81)
Query Neighborhood Hits	279	Target Neighborhood Hits	381	Shared Neighborhood Hits	66
SwissProt Accessions	Q3V1V3	Gene names	Abtap
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

AN32E_HUMAN
θ value	0.47712 (rank : 100)	NC score	0.049313 (rank : 266)
Query Neighborhood Hits	279	Target Neighborhood Hits	291	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BTT0, Q8N1S4, Q8WWW9	Gene names	ANP32E
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member E (LANP- like protein) (LANP-L).

CJ118_MOUSE
θ value	0.47712 (rank : 101)	NC score	0.052478 (rank : 234)
Query Neighborhood Hits	279	Target Neighborhood Hits	1132	Shared Neighborhood Hits	81
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

HMMR_MOUSE
θ value	0.47712 (rank : 102)	NC score	0.058075 (rank : 181)
Query Neighborhood Hits	279	Target Neighborhood Hits	1178	Shared Neighborhood Hits	101
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

LRRF1_HUMAN
θ value	0.47712 (rank : 103)	NC score	0.097110 (rank : 67)
Query Neighborhood Hits	279	Target Neighborhood Hits	625	Shared Neighborhood Hits	99
SwissProt Accessions	Q32MZ4, O75766, O75799, Q32MZ5, Q53T49, Q6PKG2	Gene names	LRRFIP1, GCF2, TRIP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (TAR RNA-interacting protein) (GC-binding factor 2).

LYRIC_HUMAN
θ value	0.47712 (rank : 104)	NC score	0.064106 (rank : 154)
Query Neighborhood Hits	279	Target Neighborhood Hits	99	Shared Neighborhood Hits	24
SwissProt Accessions	Q86UE4, Q6PK07, Q8TCX3	Gene names	MTDH, AEG1, LYRIC
Domain Architecture	No domain graphic available
Description	Protein LYRIC (Lysine-rich CEACAM1 co-isolated protein) (3D3/lyric) (Metastasis adhesion protein) (Metadherin) (Astrocyte elevated gene-1 protein) (AEG-1).

MAP1A_HUMAN
θ value	0.47712 (rank : 105)	NC score	0.104317 (rank : 59)
Query Neighborhood Hits	279	Target Neighborhood Hits	1626	Shared Neighborhood Hits	158
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MYT1L_HUMAN
θ value	0.47712 (rank : 106)	NC score	0.064727 (rank : 151)
Query Neighborhood Hits	279	Target Neighborhood Hits	471	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UL68, Q6IQ17, Q9UPP6	Gene names	MYT1L, KIAA1106
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (MyT1-L).

PCDA6_HUMAN
θ value	0.47712 (rank : 107)	NC score	0.014646 (rank : 367)
Query Neighborhood Hits	279	Target Neighborhood Hits	187	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UN73, O75283, Q9NRT8	Gene names	PCDHA6
Domain Architecture
Description	Protocadherin alpha 6 precursor (PCDH-alpha6).

ROCK1_HUMAN
θ value	0.47712 (rank : 108)	NC score	0.043967 (rank : 293)
Query Neighborhood Hits	279	Target Neighborhood Hits	2000	Shared Neighborhood Hits	104
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

WDR22_HUMAN
θ value	0.47712 (rank : 109)	NC score	0.030413 (rank : 323)
Query Neighborhood Hits	279	Target Neighborhood Hits	328	Shared Neighborhood Hits	17
SwissProt Accessions	Q96JK2, O60559, Q8N3V3, Q8N3V5	Gene names	WDR22, BCRG2, KIAA1824
Domain Architecture
Description	WD repeat protein 22 (Breakpoint cluster region protein 2) (BCRP2).

WDR22_MOUSE
θ value	0.47712 (rank : 110)	NC score	0.029190 (rank : 326)
Query Neighborhood Hits	279	Target Neighborhood Hits	302	Shared Neighborhood Hits	13
SwissProt Accessions	Q80T85, Q80VT3, Q80ZW6, Q8BIP8, Q8BVK5, Q8K0Q6	Gene names	Wdr22, Kiaa1824
Domain Architecture
Description	WD repeat protein 22.

ANR12_HUMAN
θ value	0.62314 (rank : 111)	NC score	0.057633 (rank : 187)
Query Neighborhood Hits	279	Target Neighborhood Hits	1081	Shared Neighborhood Hits	114
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

APC_MOUSE
θ value	0.62314 (rank : 112)	NC score	0.045624 (rank : 283)
Query Neighborhood Hits	279	Target Neighborhood Hits	441	Shared Neighborhood Hits	39
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

SYCP2_HUMAN
θ value	0.62314 (rank : 113)	NC score	0.077229 (rank : 113)
Query Neighborhood Hits	279	Target Neighborhood Hits	230	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BX26, O75763, Q5JX11, Q9NTX8, Q9UG27	Gene names	SYCP2, SCP2
Domain Architecture	No domain graphic available
Description	Synaptonemal complex protein 2 (SCP-2) (Synaptonemal complex lateral element protein) (hsSCP2).

ZCHC8_HUMAN
θ value	0.62314 (rank : 114)	NC score	0.036625 (rank : 313)
Query Neighborhood Hits	279	Target Neighborhood Hits	92	Shared Neighborhood Hits	15
SwissProt Accessions	Q6NZY4, Q7L2P6, Q8N2K5, Q96SK7, Q9NSS2, Q9NSS3	Gene names	ZCCHC8
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 8.

ABLM1_HUMAN
θ value	0.813845 (rank : 115)	NC score	0.006941 (rank : 389)
Query Neighborhood Hits	279	Target Neighborhood Hits	387	Shared Neighborhood Hits	7
SwissProt Accessions	O14639, Q15039, Q68CQ9, Q9BUP1	Gene names	ABLIM1, ABLIM, KIAA0059
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 1 (Actin-binding LIM protein family member 1) (abLIM-1) (Actin-binding double-zinc-finger protein) (LIMAB1) (Limatin).

AP3B2_MOUSE
θ value	0.813845 (rank : 116)	NC score	0.057003 (rank : 192)
Query Neighborhood Hits	279	Target Neighborhood Hits	246	Shared Neighborhood Hits	47
SwissProt Accessions	Q9JME5, Q6QR53, Q8R1E5	Gene names	Ap3b2
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain).

CCD46_HUMAN
θ value	0.813845 (rank : 117)	NC score	0.065782 (rank : 148)
Query Neighborhood Hits	279	Target Neighborhood Hits	1430	Shared Neighborhood Hits	116
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

K0586_HUMAN
θ value	0.813845 (rank : 118)	NC score	0.058173 (rank : 180)
Query Neighborhood Hits	279	Target Neighborhood Hits	311	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BVV6, O60328	Gene names	KIAA0586
Domain Architecture	No domain graphic available
Description	Protein KIAA0586.

MAPIP_HUMAN
θ value	0.813845 (rank : 119)	NC score	0.050536 (rank : 257)
Query Neighborhood Hits	279	Target Neighborhood Hits	3	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2Q5, Q5VY99	Gene names	MAPBPIP
Domain Architecture
Description	Mitogen-activated protein-binding protein-interacting protein (Late endosomal/lysosomal Mp1-interacting protein) (p14).

MAPIP_MOUSE
θ value	0.813845 (rank : 120)	NC score	0.050554 (rank : 256)
Query Neighborhood Hits	279	Target Neighborhood Hits	3	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JHS3	Gene names	Mapbpip
Domain Architecture
Description	Mitogen-activated protein-binding protein-interacting protein (Late endosomal/lysosomal Mp1-interacting protein) (p14).

NEST_HUMAN
θ value	0.813845 (rank : 121)	NC score	0.071186 (rank : 132)
Query Neighborhood Hits	279	Target Neighborhood Hits	1305	Shared Neighborhood Hits	125
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

PCLO_HUMAN
θ value	0.813845 (rank : 122)	NC score	0.052352 (rank : 236)
Query Neighborhood Hits	279	Target Neighborhood Hits	2046	Shared Neighborhood Hits	116
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PELP1_HUMAN
θ value	0.813845 (rank : 123)	NC score	0.065957 (rank : 146)
Query Neighborhood Hits	279	Target Neighborhood Hits	596	Shared Neighborhood Hits	60
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

RPGR1_MOUSE
θ value	0.813845 (rank : 124)	NC score	0.075607 (rank : 117)
Query Neighborhood Hits	279	Target Neighborhood Hits	713	Shared Neighborhood Hits	90
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

TTBK1_HUMAN
θ value	0.813845 (rank : 125)	NC score	0.025326 (rank : 337)
Query Neighborhood Hits	279	Target Neighborhood Hits	1058	Shared Neighborhood Hits	46
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

UBDC1_MOUSE
θ value	0.813845 (rank : 126)	NC score	0.028109 (rank : 329)
Query Neighborhood Hits	279	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VDI7, Q3TZH3	Gene names	Ubadc1, Kpc2
Domain Architecture	No domain graphic available
Description	Ubiquitin-associated domain-containing protein 1 (E3 ubiquitin-protein ligase subunit KPC2) (Kip1 ubiquitination-promoting complex protein 2).

ZCH11_HUMAN
θ value	0.813845 (rank : 127)	NC score	0.039033 (rank : 305)
Query Neighborhood Hits	279	Target Neighborhood Hits	278	Shared Neighborhood Hits	44
SwissProt Accessions	Q5TAX3, Q12764, Q5TAX4, Q86XZ3	Gene names	ZCCHC11, KIAA0191
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 11.

ADA30_HUMAN
θ value	1.06291 (rank : 128)	NC score	0.015835 (rank : 364)
Query Neighborhood Hits	279	Target Neighborhood Hits	391	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

APC_HUMAN
θ value	1.06291 (rank : 129)	NC score	0.045767 (rank : 281)
Query Neighborhood Hits	279	Target Neighborhood Hits	603	Shared Neighborhood Hits	41
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

DDX27_HUMAN
θ value	1.06291 (rank : 130)	NC score	0.014301 (rank : 368)
Query Neighborhood Hits	279	Target Neighborhood Hits	197	Shared Neighborhood Hits	28
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

GOGA4_MOUSE
θ value	1.06291 (rank : 131)	NC score	0.057672 (rank : 185)
Query Neighborhood Hits	279	Target Neighborhood Hits	1939	Shared Neighborhood Hits	138
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

IF2B_MOUSE
θ value	1.06291 (rank : 132)	NC score	0.046165 (rank : 279)
Query Neighborhood Hits	279	Target Neighborhood Hits	50	Shared Neighborhood Hits	14
SwissProt Accessions	Q99L45, Q9CSH6, Q9CT12	Gene names	Eif2s2
Domain Architecture
Description	Eukaryotic translation initiation factor 2 subunit 2 (Eukaryotic translation initiation factor 2 subunit beta) (eIF-2-beta).

K0776_MOUSE
θ value	1.06291 (rank : 133)	NC score	0.027543 (rank : 331)
Query Neighborhood Hits	279	Target Neighborhood Hits	33	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CCJ3, Q3V145, Q6ZQ50, Q8BT70, Q8C484, Q9D8I8	Gene names	Kiaa0776
Domain Architecture	No domain graphic available
Description	Protein KIAA0776.

PIGT_HUMAN
θ value	1.06291 (rank : 134)	NC score	0.037398 (rank : 311)
Query Neighborhood Hits	279	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q969N2, Q7Z3N7, Q9BQY7, Q9BQY8, Q9UJG6, Q9Y2Z5	Gene names	PIGT
Domain Architecture
Description	GPI transamidase component PIG-T precursor (Phosphatidylinositol- glycan biosynthesis class T protein).

PIGT_MOUSE
θ value	1.06291 (rank : 135)	NC score	0.037467 (rank : 309)
Query Neighborhood Hits	279	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BXQ2, Q3U2X2, Q99JA3	Gene names	Pigt, Ndap7
Domain Architecture
Description	GPI transamidase component PIG-T precursor (Phosphatidylinositol- glycan biosynthesis class T protein) (Neuronal development-associated protein 7).

RPA1_MOUSE
θ value	1.06291 (rank : 136)	NC score	0.030290 (rank : 324)
Query Neighborhood Hits	279	Target Neighborhood Hits	112	Shared Neighborhood Hits	20
SwissProt Accessions	O35134, Q7TSA9	Gene names	Polr1a, Rpa1, Rpo1-4
Domain Architecture
Description	DNA-directed RNA polymerase I largest subunit (EC 2.7.7.6) (RNA polymerase I 194 kDa subunit) (RPA194).

SLK_MOUSE
θ value	1.06291 (rank : 137)	NC score	0.040615 (rank : 301)
Query Neighborhood Hits	279	Target Neighborhood Hits	1798	Shared Neighborhood Hits	124
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

TPM4_HUMAN
θ value	1.06291 (rank : 138)	NC score	0.044398 (rank : 291)
Query Neighborhood Hits	279	Target Neighborhood Hits	525	Shared Neighborhood Hits	60
SwissProt Accessions	P67936, P07226, Q15659, Q9BU85, Q9H8Q3	Gene names	TPM4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4) (TM30p1).

ZN638_MOUSE
θ value	1.06291 (rank : 139)	NC score	0.048357 (rank : 271)
Query Neighborhood Hits	279	Target Neighborhood Hits	318	Shared Neighborhood Hits	52
SwissProt Accessions	Q61464, Q6DFV9, Q8C941	Gene names	Znf638, Np220, Zfml
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein).

ABCA2_HUMAN
θ value	1.38821 (rank : 140)	NC score	0.009402 (rank : 386)
Query Neighborhood Hits	279	Target Neighborhood Hits	143	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BZC7	Gene names	ABCA2, ABC2
Domain Architecture
Description	ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2).

BCCIP_MOUSE
θ value	1.38821 (rank : 141)	NC score	0.027702 (rank : 330)
Query Neighborhood Hits	279	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CWI3, Q9D1E0	Gene names	Bccip
Domain Architecture	No domain graphic available
Description	BRCA2 and CDKN1A-interacting protein.

CV106_HUMAN
θ value	1.38821 (rank : 142)	NC score	0.043380 (rank : 295)
Query Neighborhood Hits	279	Target Neighborhood Hits	125	Shared Neighborhood Hits	26
SwissProt Accessions	Q6P0N0, Q86V14, Q96PY4, Q9NUR5, Q9Y4X9	Gene names	C14orf106, KIAA1903
Domain Architecture	No domain graphic available
Description	Protein C14orf106 (P243).

G3BP2_HUMAN
θ value	1.38821 (rank : 143)	NC score	0.022428 (rank : 349)
Query Neighborhood Hits	279	Target Neighborhood Hits	260	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UN86, O60606, O75149, Q9UPA1	Gene names	G3BP2, KIAA0660
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 2 (GAP SH3-domain- binding protein 2) (G3BP-2).

IF2P_HUMAN
θ value	1.38821 (rank : 144)	NC score	0.090752 (rank : 79)
Query Neighborhood Hits	279	Target Neighborhood Hits	889	Shared Neighborhood Hits	98
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

KI21A_MOUSE
θ value	1.38821 (rank : 145)	NC score	0.032889 (rank : 317)
Query Neighborhood Hits	279	Target Neighborhood Hits	1317	Shared Neighborhood Hits	101
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

MDM2_HUMAN
θ value	1.38821 (rank : 146)	NC score	0.029036 (rank : 327)
Query Neighborhood Hits	279	Target Neighborhood Hits	92	Shared Neighborhood Hits	12
SwissProt Accessions	Q00987, Q13226, Q13297, Q13298, Q13299, Q13300, Q13301, Q53XW0, Q71TW9, Q9UGI3, Q9UMT8	Gene names	MDM2
Domain Architecture
Description	Ubiquitin-protein ligase E3 Mdm2 (EC 6.3.2.-) (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein) (Hdm2).

PPIG_HUMAN
θ value	1.38821 (rank : 147)	NC score	0.056217 (rank : 198)
Query Neighborhood Hits	279	Target Neighborhood Hits	670	Shared Neighborhood Hits	111
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

SENP7_HUMAN
θ value	1.38821 (rank : 148)	NC score	0.043952 (rank : 294)
Query Neighborhood Hits	279	Target Neighborhood Hits	97	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BQF6, Q96PS5, Q9C0F6, Q9HBT5	Gene names	SENP7, KIAA1707, SSP2, SUSP2
Domain Architecture
Description	Sentrin-specific protease 7 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP7) (SUMO-1-specific protease 2).

SPT6H_MOUSE
θ value	1.38821 (rank : 149)	NC score	0.039745 (rank : 302)
Query Neighborhood Hits	279	Target Neighborhood Hits	104	Shared Neighborhood Hits	22
SwissProt Accessions	Q62383, Q5SYM0, Q6GQS3, Q6ZQI0, Q8BQY6	Gene names	Supt6h, Kiaa0162
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT6.

SRBS1_HUMAN
θ value	1.38821 (rank : 150)	NC score	0.024298 (rank : 342)
Query Neighborhood Hits	279	Target Neighborhood Hits	396	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

ERIC1_HUMAN
θ value	1.81305 (rank : 151)	NC score	0.120324 (rank : 43)
Query Neighborhood Hits	279	Target Neighborhood Hits	364	Shared Neighborhood Hits	91
SwissProt Accessions	Q86X53, Q9P063	Gene names	ERICH1
Domain Architecture	No domain graphic available
Description	Glutamate-rich protein 1.

GP149_HUMAN
θ value	1.81305 (rank : 152)	NC score	0.022096 (rank : 351)
Query Neighborhood Hits	279	Target Neighborhood Hits	68	Shared Neighborhood Hits	4
SwissProt Accessions	Q86SP6	Gene names	GPR149, PGR10
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 149 (G-protein coupled receptor PGR10).

HIRP3_HUMAN
θ value	1.81305 (rank : 153)	NC score	0.078076 (rank : 109)
Query Neighborhood Hits	279	Target Neighborhood Hits	323	Shared Neighborhood Hits	61
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

LMD1_HUMAN
θ value	1.81305 (rank : 154)	NC score	0.031408 (rank : 320)
Query Neighborhood Hits	279	Target Neighborhood Hits	169	Shared Neighborhood Hits	31
SwissProt Accessions	P29536	Gene names	LMOD1
Domain Architecture
Description	Leiomodin-1 (Leiomodin, muscle form) (64 kDa autoantigen D1) (64 kDa autoantigen 1D) (64 kDa autoantigen 1D3) (Thyroid-associated ophthalmopathy autoantigen) (Smooth muscle leiomodin) (SM-Lmod).

MYST4_HUMAN
θ value	1.81305 (rank : 155)	NC score	0.057919 (rank : 182)
Query Neighborhood Hits	279	Target Neighborhood Hits	671	Shared Neighborhood Hits	96
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

NCOA7_HUMAN
θ value	1.81305 (rank : 156)	NC score	0.054037 (rank : 217)
Query Neighborhood Hits	279	Target Neighborhood Hits	160	Shared Neighborhood Hits	38
SwissProt Accessions	Q8NI08, Q3LID6, Q4G0V1, Q5TF95, Q6IPQ4, Q6NE83, Q86T89, Q8N1W4	Gene names	NCOA7, ERAP140, ESNA1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 7 (140 kDa estrogen receptor-associated protein) (Estrogen nuclear receptor coactivator 1).

PAX6_HUMAN
θ value	1.81305 (rank : 157)	NC score	0.005185 (rank : 391)
Query Neighborhood Hits	279	Target Neighborhood Hits	383	Shared Neighborhood Hits	4
SwissProt Accessions	P26367, Q6N006, Q99413	Gene names	PAX6, AN2
Domain Architecture
Description	Paired box protein Pax-6 (Oculorhombin) (Aniridia type II protein).

PAX6_MOUSE
θ value	1.81305 (rank : 158)	NC score	0.005185 (rank : 392)
Query Neighborhood Hits	279	Target Neighborhood Hits	383	Shared Neighborhood Hits	4
SwissProt Accessions	P63015, P32117, P70601, Q62222, Q64037, Q8CEI5, Q8VDB5, Q921Q8	Gene names	Pax6, Pax-6, Sey
Domain Architecture	No domain graphic available
Description	Paired box protein Pax-6 (Oculorhombin).

PPR3A_MOUSE
θ value	1.81305 (rank : 159)	NC score	0.027160 (rank : 332)
Query Neighborhood Hits	279	Target Neighborhood Hits	45	Shared Neighborhood Hits	10
SwissProt Accessions	Q99MR9, Q8BUJ4, Q8BUL0	Gene names	Ppp1r3a, Pp1g
Domain Architecture	No domain graphic available
Description	Protein phosphatase 1 regulatory subunit 3A (Protein phosphatase 1 glycogen-associated regulatory subunit) (Protein phosphatase type-1 glycogen targeting subunit) (RGL).

RENT2_HUMAN
θ value	1.81305 (rank : 160)	NC score	0.068928 (rank : 139)
Query Neighborhood Hits	279	Target Neighborhood Hits	618	Shared Neighborhood Hits	74
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

REST_MOUSE
θ value	1.81305 (rank : 161)	NC score	0.053357 (rank : 225)
Query Neighborhood Hits	279	Target Neighborhood Hits	1506	Shared Neighborhood Hits	113
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

SRBS1_MOUSE
θ value	1.81305 (rank : 162)	NC score	0.021284 (rank : 354)
Query Neighborhood Hits	279	Target Neighborhood Hits	409	Shared Neighborhood Hits	27
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

HOME2_MOUSE
θ value	2.36792 (rank : 163)	NC score	0.048757 (rank : 268)
Query Neighborhood Hits	279	Target Neighborhood Hits	882	Shared Neighborhood Hits	89
SwissProt Accessions	Q9QWW1, O89025, Q9Z0E4	Gene names	Homer2, Vesl2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up- regulated during seizure and LTP 2) (Vesl-2).

IF38_HUMAN
θ value	2.36792 (rank : 164)	NC score	0.042129 (rank : 297)
Query Neighborhood Hits	279	Target Neighborhood Hits	98	Shared Neighborhood Hits	20
SwissProt Accessions	Q99613, O00215	Gene names	EIF3S8
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 8 (eIF3 p110) (eIF3c).

JIP2_HUMAN
θ value	2.36792 (rank : 165)	NC score	0.022489 (rank : 348)
Query Neighborhood Hits	279	Target Neighborhood Hits	288	Shared Neighborhood Hits	18
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

LUZP1_HUMAN
θ value	2.36792 (rank : 166)	NC score	0.046472 (rank : 277)
Query Neighborhood Hits	279	Target Neighborhood Hits	739	Shared Neighborhood Hits	63
SwissProt Accessions	Q86V48, Q5TH93, Q8N4X3, Q8TEH1	Gene names	LUZP1
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1.

MFAP1_MOUSE
θ value	2.36792 (rank : 167)	NC score	0.075120 (rank : 119)
Query Neighborhood Hits	279	Target Neighborhood Hits	353	Shared Neighborhood Hits	54
SwissProt Accessions	Q9CQU1, Q3TU29, Q8CCL1, Q9CSJ5	Gene names	Mfap1
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 1.

MPP8_HUMAN
θ value	2.36792 (rank : 168)	NC score	0.072377 (rank : 125)
Query Neighborhood Hits	279	Target Neighborhood Hits	948	Shared Neighborhood Hits	125
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

NEK2_MOUSE
θ value	2.36792 (rank : 169)	NC score	0.036261 (rank : 314)
Query Neighborhood Hits	279	Target Neighborhood Hits	876	Shared Neighborhood Hits	20
SwissProt Accessions	O35942, O35959	Gene names	Nek2
Domain Architecture
Description	Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (NimA-related protein kinase 2).

NUMA1_HUMAN
θ value	2.36792 (rank : 170)	NC score	0.048744 (rank : 269)
Query Neighborhood Hits	279	Target Neighborhood Hits	1523	Shared Neighborhood Hits	93
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

PCDA3_HUMAN
θ value	2.36792 (rank : 171)	NC score	0.013196 (rank : 374)
Query Neighborhood Hits	279	Target Neighborhood Hits	203	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y5H8, O75286	Gene names	PCDHA3
Domain Architecture
Description	Protocadherin alpha 3 precursor (PCDH-alpha3).

PCDA8_HUMAN
θ value	2.36792 (rank : 172)	NC score	0.013414 (rank : 372)
Query Neighborhood Hits	279	Target Neighborhood Hits	187	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y5H6, O75281	Gene names	PCDHA8
Domain Architecture
Description	Protocadherin alpha 8 precursor (PCDH-alpha8).

PSIP1_HUMAN
θ value	2.36792 (rank : 173)	NC score	0.072405 (rank : 124)
Query Neighborhood Hits	279	Target Neighborhood Hits	341	Shared Neighborhood Hits	79
SwissProt Accessions	O75475, O00256, O95368, Q6P391, Q86YB9, Q9NZI3, Q9UER6	Gene names	PSIP1, DFS70, LEDGF, PSIP2
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (Transcriptional coactivator p75/p52) (Dense fine speckles 70 kDa protein) (DFS 70) (CLL-associated antigen KW-7).

PTMA_HUMAN
θ value	2.36792 (rank : 174)	NC score	0.095061 (rank : 73)
Query Neighborhood Hits	279	Target Neighborhood Hits	88	Shared Neighborhood Hits	23
SwissProt Accessions	P06454, Q15249, Q15592	Gene names	PTMA, TMSA
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha-1].

RERE_MOUSE
θ value	2.36792 (rank : 175)	NC score	0.026962 (rank : 334)
Query Neighborhood Hits	279	Target Neighborhood Hits	785	Shared Neighborhood Hits	47
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

RFC1_MOUSE
θ value	2.36792 (rank : 176)	NC score	0.044681 (rank : 289)
Query Neighborhood Hits	279	Target Neighborhood Hits	290	Shared Neighborhood Hits	55
SwissProt Accessions	P35601	Gene names	Rfc1, Ibf-1, Recc1
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (A1-P145) (Differentiation- specific element-binding protein) (ISRE-binding protein).

SLK_HUMAN
θ value	2.36792 (rank : 177)	NC score	0.044244 (rank : 292)
Query Neighborhood Hits	279	Target Neighborhood Hits	1775	Shared Neighborhood Hits	123
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

SMCA4_HUMAN
θ value	2.36792 (rank : 178)	NC score	0.020357 (rank : 356)
Query Neighborhood Hits	279	Target Neighborhood Hits	597	Shared Neighborhood Hits	49
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

WDHD1_MOUSE
θ value	2.36792 (rank : 179)	NC score	0.022885 (rank : 346)
Query Neighborhood Hits	279	Target Neighborhood Hits	414	Shared Neighborhood Hits	29
SwissProt Accessions	P59328, Q6P408	Gene names	Wdhd1, And1
Domain Architecture	No domain graphic available
Description	WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA- binding protein 1) (And-1).

BRCA1_HUMAN
θ value	3.0926 (rank : 180)	NC score	0.020243 (rank : 357)
Query Neighborhood Hits	279	Target Neighborhood Hits	381	Shared Neighborhood Hits	34
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

CA026_HUMAN
θ value	3.0926 (rank : 181)	NC score	0.025179 (rank : 339)
Query Neighborhood Hits	279	Target Neighborhood Hits	87	Shared Neighborhood Hits	16
SwissProt Accessions	Q5T5J6, Q8NEK9, Q9BZQ7, Q9NXQ0	Gene names	C1orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf26.

GRAP1_HUMAN
θ value	3.0926 (rank : 182)	NC score	0.046425 (rank : 278)
Query Neighborhood Hits	279	Target Neighborhood Hits	944	Shared Neighborhood Hits	63
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

MAP9_HUMAN
θ value	3.0926 (rank : 183)	NC score	0.071959 (rank : 127)
Query Neighborhood Hits	279	Target Neighborhood Hits	518	Shared Neighborhood Hits	78
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

MYC_HUMAN
θ value	3.0926 (rank : 184)	NC score	0.012821 (rank : 377)
Query Neighborhood Hits	279	Target Neighborhood Hits	146	Shared Neighborhood Hits	7
SwissProt Accessions	P01106, P01107, Q14026	Gene names	MYC
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

NEK1_MOUSE
θ value	3.0926 (rank : 185)	NC score	0.049227 (rank : 267)
Query Neighborhood Hits	279	Target Neighborhood Hits	1311	Shared Neighborhood Hits	108
SwissProt Accessions	P51954	Gene names	Nek1
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1).

OLR1_MOUSE
θ value	3.0926 (rank : 186)	NC score	0.032487 (rank : 318)
Query Neighborhood Hits	279	Target Neighborhood Hits	596	Shared Neighborhood Hits	43
SwissProt Accessions	Q9EQ09	Gene names	Olr1, Lox1
Domain Architecture	No domain graphic available
Description	Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1) (Lectin-type oxidized LDL receptor 1) (Lectin-like oxidized LDL receptor 1) (Lectin-like oxLDL receptor 1) (LOX-1) [Contains: Oxidized low-density lipoprotein receptor 1, soluble form].

PCDA9_HUMAN
θ value	3.0926 (rank : 187)	NC score	0.013206 (rank : 373)
Query Neighborhood Hits	279	Target Neighborhood Hits	203	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y5H5, O15053	Gene names	PCDHA9, KIAA0345
Domain Architecture
Description	Protocadherin alpha 9 precursor (PCDH-alpha9).

PHF3_HUMAN
θ value	3.0926 (rank : 188)	NC score	0.041438 (rank : 299)
Query Neighborhood Hits	279	Target Neighborhood Hits	419	Shared Neighborhood Hits	48
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

PSIP1_MOUSE
θ value	3.0926 (rank : 189)	NC score	0.057196 (rank : 191)
Query Neighborhood Hits	279	Target Neighborhood Hits	313	Shared Neighborhood Hits	67
SwissProt Accessions	Q99JF8, Q3TEJ7, Q3TTD7, Q3UTA1, Q80WQ7, Q99JF7, Q99LR4, Q9CT03	Gene names	Psip1, Ledgf
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (mLEDGF).

ROCK1_MOUSE
θ value	3.0926 (rank : 190)	NC score	0.044890 (rank : 288)
Query Neighborhood Hits	279	Target Neighborhood Hits	2126	Shared Neighborhood Hits	111
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

SEC63_MOUSE
θ value	3.0926 (rank : 191)	NC score	0.071190 (rank : 131)
Query Neighborhood Hits	279	Target Neighborhood Hits	601	Shared Neighborhood Hits	112
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

SYNE1_HUMAN
θ value	3.0926 (rank : 192)	NC score	0.038163 (rank : 307)
Query Neighborhood Hits	279	Target Neighborhood Hits	1484	Shared Neighborhood Hits	76
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

TXD13_HUMAN
θ value	3.0926 (rank : 193)	NC score	0.046500 (rank : 276)
Query Neighborhood Hits	279	Target Neighborhood Hits	106	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H1E5, Q8N4P7, Q8NCC1, Q9UJA1, Q9ULQ8	Gene names	TXNDC13, KIAA1162
Domain Architecture
Description	Thioredoxin domain-containing protein 13 precursor.

AP3B1_HUMAN
θ value	4.03905 (rank : 194)	NC score	0.050191 (rank : 261)
Query Neighborhood Hits	279	Target Neighborhood Hits	283	Shared Neighborhood Hits	49
SwissProt Accessions	O00203, O00580, Q7Z393, Q9HD66	Gene names	AP3B1, ADTB3A
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

AP4E1_HUMAN
θ value	4.03905 (rank : 195)	NC score	0.012144 (rank : 382)
Query Neighborhood Hits	279	Target Neighborhood Hits	57	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UPM8, Q9Y588	Gene names	AP4E1
Domain Architecture
Description	AP-4 complex subunit epsilon-1 (Adapter-related protein complex 4 epsilon-1 subunit) (Epsilon subunit of AP-4) (AP-4 adapter complex epsilon subunit).

GON4L_MOUSE
θ value	4.03905 (rank : 196)	NC score	0.046822 (rank : 275)
Query Neighborhood Hits	279	Target Neighborhood Hits	455	Shared Neighborhood Hits	55
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

IPP2_MOUSE
θ value	4.03905 (rank : 197)	NC score	0.022504 (rank : 347)
Query Neighborhood Hits	279	Target Neighborhood Hits	49	Shared Neighborhood Hits	8
SwissProt Accessions	Q9DCL8, Q3UD25, Q8C1A6	Gene names	Ppp1r2
Domain Architecture	No domain graphic available
Description	Protein phosphatase inhibitor 2 (IPP-2).

MIER1_MOUSE
θ value	4.03905 (rank : 198)	NC score	0.022033 (rank : 352)
Query Neighborhood Hits	279	Target Neighborhood Hits	84	Shared Neighborhood Hits	14
SwissProt Accessions	Q5UAK0, Q5UAK1, Q5UAK2, Q5UAK3, Q6ZPL6, Q9D402	Gene names	Mier1, Kiaa1610
Domain Architecture	No domain graphic available
Description	Mesoderm induction early response protein 1 (Mi-er1).

OPTN_MOUSE
θ value	4.03905 (rank : 199)	NC score	0.053497 (rank : 222)
Query Neighborhood Hits	279	Target Neighborhood Hits	1120	Shared Neighborhood Hits	101
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

PCDA1_HUMAN
θ value	4.03905 (rank : 200)	NC score	0.012830 (rank : 376)
Query Neighborhood Hits	279	Target Neighborhood Hits	199	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y5I3, O75288, Q9NRT7	Gene names	PCDHA1
Domain Architecture
Description	Protocadherin alpha 1 precursor (PCDH-alpha1).

PCDAB_HUMAN
θ value	4.03905 (rank : 201)	NC score	0.012791 (rank : 378)
Query Neighborhood Hits	279	Target Neighborhood Hits	211	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y5I1, O75279	Gene names	PCDHA11
Domain Architecture
Description	Protocadherin alpha 11 precursor (PCDH-alpha11).

RBBP6_HUMAN
θ value	4.03905 (rank : 202)	NC score	0.101049 (rank : 62)
Query Neighborhood Hits	279	Target Neighborhood Hits	1135	Shared Neighborhood Hits	138
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RBBP6_MOUSE
θ value	4.03905 (rank : 203)	NC score	0.099474 (rank : 65)
Query Neighborhood Hits	279	Target Neighborhood Hits	1014	Shared Neighborhood Hits	127
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

SPT6H_HUMAN
θ value	4.03905 (rank : 204)	NC score	0.037409 (rank : 310)
Query Neighborhood Hits	279	Target Neighborhood Hits	104	Shared Neighborhood Hits	22
SwissProt Accessions	Q7KZ85, Q15737, Q6GMQ4, Q7KYW9, Q7LDK4, Q8N526, Q92775, Q96AH3, Q9BTH9, Q9BTI2	Gene names	SUPT6H, KIAA0162, SPT6H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT6 (hSPT6) (Tat-cotransactivator 2 protein) (Tat-CT2 protein).

ABCA5_MOUSE
θ value	5.27518 (rank : 205)	NC score	0.004776 (rank : 393)
Query Neighborhood Hits	279	Target Neighborhood Hits	137	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K448, Q3TE17, Q3UUB4, Q6P1Y0, Q6ZPG4, Q810C7, Q8BM46, Q8BXG7	Gene names	Abca5, Kiaa1888
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 5.

AHI1_HUMAN
θ value	5.27518 (rank : 206)	NC score	0.006528 (rank : 390)
Query Neighborhood Hits	279	Target Neighborhood Hits	537	Shared Neighborhood Hits	20
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

AKAP2_HUMAN
θ value	5.27518 (rank : 207)	NC score	0.025645 (rank : 336)
Query Neighborhood Hits	279	Target Neighborhood Hits	507	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

CD2L1_HUMAN
θ value	5.27518 (rank : 208)	NC score	0.037488 (rank : 308)
Query Neighborhood Hits	279	Target Neighborhood Hits	1467	Shared Neighborhood Hits	94
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

CF010_HUMAN
θ value	5.27518 (rank : 209)	NC score	0.095528 (rank : 71)
Query Neighborhood Hits	279	Target Neighborhood Hits	329	Shared Neighborhood Hits	79
SwissProt Accessions	Q5SRN2, Q5SPI9, Q5SPJ0, Q5SPK9, Q5SPL0, Q5SRN3, Q5TG25, Q5TG26, Q8N4B6	Gene names	C6orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf10.

CIR_MOUSE
θ value	5.27518 (rank : 210)	NC score	0.038610 (rank : 306)
Query Neighborhood Hits	279	Target Neighborhood Hits	255	Shared Neighborhood Hits	35
SwissProt Accessions	Q9DA19, Q3V2N9, Q4KL44, Q52KL9, Q5FW66	Gene names	Cir
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor.

EEA1_HUMAN
θ value	5.27518 (rank : 211)	NC score	0.047800 (rank : 273)
Query Neighborhood Hits	279	Target Neighborhood Hits	1796	Shared Neighborhood Hits	124
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

GOGA4_HUMAN
θ value	5.27518 (rank : 212)	NC score	0.057698 (rank : 184)
Query Neighborhood Hits	279	Target Neighborhood Hits	2034	Shared Neighborhood Hits	141
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

HM20A_HUMAN
θ value	5.27518 (rank : 213)	NC score	0.030168 (rank : 325)
Query Neighborhood Hits	279	Target Neighborhood Hits	343	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NP66, Q53G31, Q9NSF6	Gene names	HMG20A, HMGX1
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (HMG domain-containing protein HMGX1).

HM20A_MOUSE
θ value	5.27518 (rank : 214)	NC score	0.031032 (rank : 321)
Query Neighborhood Hits	279	Target Neighborhood Hits	348	Shared Neighborhood Hits	55
SwissProt Accessions	Q9DC33, Q3LSF9, Q6NV87, Q8BSK1, Q8C3C1, Q8CAA0, Q9CYG2	Gene names	Hmg20a, Ibraf
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (iBRAF) (Inhibitor of BRAF35) (HMG domain protein HMGX1).

IF2B_HUMAN
θ value	5.27518 (rank : 215)	NC score	0.034838 (rank : 316)
Query Neighborhood Hits	279	Target Neighborhood Hits	60	Shared Neighborhood Hits	17
SwissProt Accessions	P20042, Q9BVU0, Q9UJE4	Gene names	EIF2S2, EIF2B
Domain Architecture
Description	Eukaryotic translation initiation factor 2 subunit 2 (Eukaryotic translation initiation factor 2 subunit beta) (eIF-2-beta).

KU70_MOUSE
θ value	5.27518 (rank : 216)	NC score	0.013510 (rank : 371)
Query Neighborhood Hits	279	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	P23475, O88212, Q62027, Q62382, Q62453	Gene names	Xrcc6, G22p1, Ku70
Domain Architecture
Description	ATP-dependent DNA helicase 2 subunit 1 (EC 3.6.1.-) (ATP-dependent DNA helicase II 70 kDa subunit) (Ku autoantigen protein p70 homolog) (Ku70) (CTC box-binding factor 75 kDa subunit) (CTCBF) (CTC75) (DNA- repair protein XRCC6).

MAP9_MOUSE
θ value	5.27518 (rank : 217)	NC score	0.063779 (rank : 156)
Query Neighborhood Hits	279	Target Neighborhood Hits	529	Shared Neighborhood Hits	79
SwissProt Accessions	Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7	Gene names	Map9, Asap
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

MFAP1_HUMAN
θ value	5.27518 (rank : 218)	NC score	0.075166 (rank : 118)
Query Neighborhood Hits	279	Target Neighborhood Hits	321	Shared Neighborhood Hits	57
SwissProt Accessions	P55081	Gene names	MFAP1
Domain Architecture
Description	Microfibrillar-associated protein 1.

MLL3_MOUSE
θ value	5.27518 (rank : 219)	NC score	0.021147 (rank : 355)
Query Neighborhood Hits	279	Target Neighborhood Hits	1399	Shared Neighborhood Hits	77
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MSH6_HUMAN
θ value	5.27518 (rank : 220)	NC score	0.016352 (rank : 363)
Query Neighborhood Hits	279	Target Neighborhood Hits	81	Shared Neighborhood Hits	13
SwissProt Accessions	P52701, O43706, O43917, Q8TCX4, Q9BTB5	Gene names	MSH6, GTBP
Domain Architecture
Description	DNA mismatch repair protein MSH6 (MutS-alpha 160 kDa subunit) (G/T mismatch-binding protein) (GTBP) (GTMBP) (p160).

MYT1_MOUSE
θ value	5.27518 (rank : 221)	NC score	0.049499 (rank : 265)
Query Neighborhood Hits	279	Target Neighborhood Hits	385	Shared Neighborhood Hits	58
SwissProt Accessions	Q8CFC2, O08995, Q8CFH1	Gene names	Myt1, Kiaa0835, Nzf2
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1 (MyT1) (Neural zinc finger factor 2) (NZF-2).

NUCL_MOUSE
θ value	5.27518 (rank : 222)	NC score	0.049558 (rank : 264)
Query Neighborhood Hits	279	Target Neighborhood Hits	425	Shared Neighborhood Hits	38
SwissProt Accessions	P09405, Q548M9, Q61991, Q99K50	Gene names	Ncl, Nuc
Domain Architecture
Description	Nucleolin (Protein C23).

PZRN4_HUMAN
θ value	5.27518 (rank : 223)	NC score	0.008049 (rank : 388)
Query Neighborhood Hits	279	Target Neighborhood Hits	438	Shared Neighborhood Hits	20
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

TPR_HUMAN
θ value	5.27518 (rank : 224)	NC score	0.060878 (rank : 171)
Query Neighborhood Hits	279	Target Neighborhood Hits	1921	Shared Neighborhood Hits	148
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

UACA_HUMAN
θ value	5.27518 (rank : 225)	NC score	0.045210 (rank : 285)
Query Neighborhood Hits	279	Target Neighborhood Hits	1622	Shared Neighborhood Hits	112
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

ZN694_HUMAN
θ value	5.27518 (rank : 226)	NC score	-0.006565 (rank : 395)
Query Neighborhood Hits	279	Target Neighborhood Hits	764	Shared Neighborhood Hits	7
SwissProt Accessions	Q63HK3, Q6ZN77	Gene names	ZNF694
Domain Architecture	No domain graphic available
Description	Zinc finger protein 694.

AN32B_HUMAN
θ value	6.88961 (rank : 227)	NC score	0.046096 (rank : 280)
Query Neighborhood Hits	279	Target Neighborhood Hits	243	Shared Neighborhood Hits	25
SwissProt Accessions	Q92688, O00655, P78458, P78459	Gene names	ANP32B, APRIL, PHAPI2
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member B (PHAPI2 protein) (Silver-stainable protein SSP29) (Acidic protein rich in leucines).

ARI4A_HUMAN
θ value	6.88961 (rank : 228)	NC score	0.058508 (rank : 178)
Query Neighborhood Hits	279	Target Neighborhood Hits	434	Shared Neighborhood Hits	64
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

BBX_MOUSE
θ value	6.88961 (rank : 229)	NC score	0.008903 (rank : 387)
Query Neighborhood Hits	279	Target Neighborhood Hits	152	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VBW5, Q3TZK1, Q6NXY8, Q6PEU3, Q8BQJ7, Q8C7E0, Q8CDQ0, Q8CDV1, Q8VI48, Q8VI49, Q8VI50, Q9CS94	Gene names	Bbx, Hbp2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

BRE1A_MOUSE
θ value	6.88961 (rank : 230)	NC score	0.047862 (rank : 272)
Query Neighborhood Hits	279	Target Neighborhood Hits	1025	Shared Neighborhood Hits	81
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

GOGA5_HUMAN
θ value	6.88961 (rank : 231)	NC score	0.047161 (rank : 274)
Query Neighborhood Hits	279	Target Neighborhood Hits	1168	Shared Neighborhood Hits	92
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

JHD2C_MOUSE
θ value	6.88961 (rank : 232)	NC score	0.017768 (rank : 361)
Query Neighborhood Hits	279	Target Neighborhood Hits	297	Shared Neighborhood Hits	46
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

MSH6_MOUSE
θ value	6.88961 (rank : 233)	NC score	0.013994 (rank : 369)
Query Neighborhood Hits	279	Target Neighborhood Hits	55	Shared Neighborhood Hits	8
SwissProt Accessions	P54276, O54710	Gene names	Msh6, Gtmbp
Domain Architecture
Description	DNA mismatch repair protein MSH6 (MutS-alpha 160 kDa subunit) (G/T mismatch-binding protein) (GTBP) (GTMBP) (p160).

MYH11_HUMAN
θ value	6.88961 (rank : 234)	NC score	0.039360 (rank : 303)
Query Neighborhood Hits	279	Target Neighborhood Hits	1806	Shared Neighborhood Hits	139
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYT1_HUMAN
θ value	6.88961 (rank : 235)	NC score	0.051045 (rank : 251)
Query Neighborhood Hits	279	Target Neighborhood Hits	475	Shared Neighborhood Hits	72
SwissProt Accessions	Q01538, O94922, Q9UPV2	Gene names	MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1
Domain Architecture
Description	Myelin transcription factor 1 (MyT1) (MyTI) (Proteolipid protein- binding protein) (PLPB1).

NCOR1_HUMAN
θ value	6.88961 (rank : 236)	NC score	0.035466 (rank : 315)
Query Neighborhood Hits	279	Target Neighborhood Hits	577	Shared Neighborhood Hits	78
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

NPHP1_HUMAN
θ value	6.88961 (rank : 237)	NC score	0.012900 (rank : 375)
Query Neighborhood Hits	279	Target Neighborhood Hits	288	Shared Neighborhood Hits	18
SwissProt Accessions	O15259, O14837	Gene names	NPHP1, NPH1
Domain Architecture
Description	Nephrocystin-1 (Juvenile nephronophthisis 1 protein).

OSTP_HUMAN
θ value	6.88961 (rank : 238)	NC score	0.023771 (rank : 343)
Query Neighborhood Hits	279	Target Neighborhood Hits	36	Shared Neighborhood Hits	11
SwissProt Accessions	P10451, Q15681, Q15682, Q15683, Q8NBK2, Q96IZ1	Gene names	SPP1, OPN
Domain Architecture
Description	Osteopontin precursor (Bone sialoprotein-1) (Secreted phosphoprotein 1) (SPP-1) (Urinary stone protein) (Nephropontin) (Uropontin).

PCDA7_HUMAN
θ value	6.88961 (rank : 239)	NC score	0.012589 (rank : 380)
Query Neighborhood Hits	279	Target Neighborhood Hits	221	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UN72, O75282	Gene names	PCDHA7
Domain Architecture
Description	Protocadherin alpha 7 precursor (PCDH-alpha7).

PCDAA_HUMAN
θ value	6.88961 (rank : 240)	NC score	0.012669 (rank : 379)
Query Neighborhood Hits	279	Target Neighborhood Hits	183	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y5I2, O75280, Q9NRU2	Gene names	PCDHA10
Domain Architecture
Description	Protocadherin alpha 10 precursor (PCDH-alpha10).

PMS1_HUMAN
θ value	6.88961 (rank : 241)	NC score	0.013800 (rank : 370)
Query Neighborhood Hits	279	Target Neighborhood Hits	126	Shared Neighborhood Hits	12
SwissProt Accessions	P54277	Gene names	PMS1, PMSL1
Domain Architecture
Description	PMS1 protein homolog 1 (DNA mismatch repair protein PMS1).

PRDM2_HUMAN
θ value	6.88961 (rank : 242)	NC score	0.003717 (rank : 394)
Query Neighborhood Hits	279	Target Neighborhood Hits	1135	Shared Neighborhood Hits	38
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

PRG4_HUMAN
θ value	6.88961 (rank : 243)	NC score	0.023452 (rank : 344)
Query Neighborhood Hits	279	Target Neighborhood Hits	764	Shared Neighborhood Hits	36
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PTRF_MOUSE
θ value	6.88961 (rank : 244)	NC score	0.025288 (rank : 338)
Query Neighborhood Hits	279	Target Neighborhood Hits	151	Shared Neighborhood Hits	19
SwissProt Accessions	O54724	Gene names	Ptrf
Domain Architecture	No domain graphic available
Description	Polymerase I and transcript release factor.

RPA1_HUMAN
θ value	6.88961 (rank : 245)	NC score	0.023377 (rank : 345)
Query Neighborhood Hits	279	Target Neighborhood Hits	106	Shared Neighborhood Hits	15
SwissProt Accessions	O95602, Q9UEH0, Q9UFT9	Gene names	POLR1A
Domain Architecture
Description	DNA-directed RNA polymerase I largest subunit (EC 2.7.7.6) (RNA polymerase I 194 kDa subunit) (RPA194).

SETB1_MOUSE
θ value	6.88961 (rank : 246)	NC score	0.010085 (rank : 385)
Query Neighborhood Hits	279	Target Neighborhood Hits	150	Shared Neighborhood Hits	13
SwissProt Accessions	O88974, Q922K1	Gene names	Setdb1, Eset
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

SMCE1_HUMAN
θ value	6.88961 (rank : 247)	NC score	0.041177 (rank : 300)
Query Neighborhood Hits	279	Target Neighborhood Hits	272	Shared Neighborhood Hits	38
SwissProt Accessions	Q969G3, O43539	Gene names	SMARCE1, BAF57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 (BRG1-associated factor 57).

TP53B_HUMAN
θ value	6.88961 (rank : 248)	NC score	0.057599 (rank : 188)
Query Neighborhood Hits	279	Target Neighborhood Hits	413	Shared Neighborhood Hits	62
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TRIPB_HUMAN
θ value	6.88961 (rank : 249)	NC score	0.063185 (rank : 159)
Query Neighborhood Hits	279	Target Neighborhood Hits	1587	Shared Neighborhood Hits	121
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

UT14A_MOUSE
θ value	6.88961 (rank : 250)	NC score	0.022294 (rank : 350)
Query Neighborhood Hits	279	Target Neighborhood Hits	177	Shared Neighborhood Hits	27
SwissProt Accessions	Q640M1, Q6A094, Q6EJB4, Q6P6L1, Q9CZK8	Gene names	Utp14a, JsdX, Kiaa0266
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 14 homolog A (Juvenile spermatogonial depletion-like X-linked protein) (Jsd-like X-linked protein).

WDR60_MOUSE
θ value	6.88961 (rank : 251)	NC score	0.039072 (rank : 304)
Query Neighborhood Hits	279	Target Neighborhood Hits	344	Shared Neighborhood Hits	52
SwissProt Accessions	Q8C761, Q3UNM4	Gene names	Wdr60
Domain Architecture	No domain graphic available
Description	WD repeat protein 60.

ABCF1_HUMAN
θ value	8.99809 (rank : 252)	NC score	0.026134 (rank : 335)
Query Neighborhood Hits	279	Target Neighborhood Hits	343	Shared Neighborhood Hits	45
SwissProt Accessions	Q8NE71, O14897, Q69YP6	Gene names	ABCF1, ABC50
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50) (TNF-alpha-stimulated ABC protein).

AMOL2_HUMAN
θ value	8.99809 (rank : 253)	NC score	0.028239 (rank : 328)
Query Neighborhood Hits	279	Target Neighborhood Hits	603	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y2J4, Q53EP1, Q96F99, Q9UKB4	Gene names	AMOTL2, KIAA0989
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2 (Leman coiled-coil protein) (LCCP).

AN32E_MOUSE
θ value	8.99809 (rank : 254)	NC score	0.030726 (rank : 322)
Query Neighborhood Hits	279	Target Neighborhood Hits	257	Shared Neighborhood Hits	18
SwissProt Accessions	P97822, Q3TH89, Q8BPF8, Q8C2L4, Q8C7Q8, Q9CZD2	Gene names	Anp32e, Cpd1
Domain Architecture
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member E (LANP- like protein) (LANP-L) (Cerebellar postnatal development protein 1).

AR13B_HUMAN
θ value	8.99809 (rank : 255)	NC score	0.020212 (rank : 358)
Query Neighborhood Hits	279	Target Neighborhood Hits	528	Shared Neighborhood Hits	70
SwissProt Accessions	Q3SXY8, Q504W8	Gene names	ARL13B, ARL2L1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-like protein 13B (ADP-ribosylation factor-like protein 2-like 1) (ARL2-like protein 1).

BAZ2B_HUMAN
θ value	8.99809 (rank : 256)	NC score	0.041518 (rank : 298)
Query Neighborhood Hits	279	Target Neighborhood Hits	803	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

CASC3_HUMAN
θ value	8.99809 (rank : 257)	NC score	0.031461 (rank : 319)
Query Neighborhood Hits	279	Target Neighborhood Hits	204	Shared Neighborhood Hits	40
SwissProt Accessions	O15234	Gene names	CASC3, MLN51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein) (Metastatic lymph node protein 51) (Protein MLN 51) (Protein barentsz) (Btz).

CHD4_HUMAN
θ value	8.99809 (rank : 258)	NC score	0.019146 (rank : 359)
Query Neighborhood Hits	279	Target Neighborhood Hits	365	Shared Neighborhood Hits	40
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CI082_HUMAN
θ value	8.99809 (rank : 259)	NC score	0.011357 (rank : 383)
Query Neighborhood Hits	279	Target Neighborhood Hits	32	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H8G2, Q5VY32, Q6IPE6, Q96C59	Gene names	C9orf82
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf82.

CJ068_HUMAN
θ value	8.99809 (rank : 260)	NC score	0.059421 (rank : 177)
Query Neighborhood Hits	279	Target Neighborhood Hits	316	Shared Neighborhood Hits	59
SwissProt Accessions	Q9H943, Q8N7T7	Gene names	C10orf68
Domain Architecture	No domain graphic available
Description	Protein C10orf68.

CROCC_MOUSE
θ value	8.99809 (rank : 261)	NC score	0.045558 (rank : 284)
Query Neighborhood Hits	279	Target Neighborhood Hits	1460	Shared Neighborhood Hits	102
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

CTDP1_MOUSE
θ value	8.99809 (rank : 262)	NC score	0.017796 (rank : 360)
Query Neighborhood Hits	279	Target Neighborhood Hits	146	Shared Neighborhood Hits	16
SwissProt Accessions	Q7TSG2, Q7TSS7, Q9D4S8	Gene names	Ctdp1, Fcp1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

DAXX_HUMAN
θ value	8.99809 (rank : 263)	NC score	0.064938 (rank : 150)
Query Neighborhood Hits	279	Target Neighborhood Hits	207	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UER7, O14747, O15141, O15208, Q9BWI3	Gene names	DAXX, BING2, DAP6
Domain Architecture
Description	Death domain-associated protein 6 (Daxx) (hDaxx) (Fas death domain- associated protein) (ETS1-associated protein 1) (EAP1).

DDX21_HUMAN
θ value	8.99809 (rank : 264)	NC score	0.015077 (rank : 365)
Query Neighborhood Hits	279	Target Neighborhood Hits	308	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DNL1_HUMAN
θ value	8.99809 (rank : 265)	NC score	0.021693 (rank : 353)
Query Neighborhood Hits	279	Target Neighborhood Hits	216	Shared Neighborhood Hits	25
SwissProt Accessions	P18858	Gene names	LIG1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

HS90A_HUMAN
θ value	8.99809 (rank : 266)	NC score	0.014761 (rank : 366)
Query Neighborhood Hits	279	Target Neighborhood Hits	144	Shared Neighborhood Hits	29
SwissProt Accessions	P07900, Q2PP14, Q9BVQ5	Gene names	HSP90AA1, HSP90A, HSPC1, HSPCA
Domain Architecture
Description	Heat shock protein HSP 90-alpha (HSP 86) (NY-REN-38 antigen).

LMO7_HUMAN
θ value	8.99809 (rank : 267)	NC score	0.045680 (rank : 282)
Query Neighborhood Hits	279	Target Neighborhood Hits	507	Shared Neighborhood Hits	48
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

LYAR_MOUSE
θ value	8.99809 (rank : 268)	NC score	0.024571 (rank : 341)
Query Neighborhood Hits	279	Target Neighborhood Hits	153	Shared Neighborhood Hits	25
SwissProt Accessions	Q08288, Q9D9X2	Gene names	Lyar
Domain Architecture	No domain graphic available
Description	Cell growth-regulating nucleolar protein.

NASP_HUMAN
θ value	8.99809 (rank : 269)	NC score	0.130315 (rank : 39)
Query Neighborhood Hits	279	Target Neighborhood Hits	709	Shared Neighborhood Hits	136
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

PCDA4_HUMAN
θ value	8.99809 (rank : 270)	NC score	0.012536 (rank : 381)
Query Neighborhood Hits	279	Target Neighborhood Hits	193	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UN74, O75285	Gene names	PCDHA4
Domain Architecture
Description	Protocadherin alpha 4 precursor (PCDH-alpha4).

PCNT_HUMAN
θ value	8.99809 (rank : 271)	NC score	0.045154 (rank : 287)
Query Neighborhood Hits	279	Target Neighborhood Hits	1551	Shared Neighborhood Hits	102
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

RERE_HUMAN
θ value	8.99809 (rank : 272)	NC score	0.025138 (rank : 340)
Query Neighborhood Hits	279	Target Neighborhood Hits	779	Shared Neighborhood Hits	46
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

RHG25_HUMAN
θ value	8.99809 (rank : 273)	NC score	0.016787 (rank : 362)
Query Neighborhood Hits	279	Target Neighborhood Hits	550	Shared Neighborhood Hits	51
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

SAS6_HUMAN
θ value	8.99809 (rank : 274)	NC score	0.045173 (rank : 286)
Query Neighborhood Hits	279	Target Neighborhood Hits	791	Shared Neighborhood Hits	66
SwissProt Accessions	Q6UVJ0, Q8N3K0	Gene names	SASS6, SAS6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog (HsSAS-6).

SEC63_HUMAN
θ value	8.99809 (rank : 275)	NC score	0.066932 (rank : 142)
Query Neighborhood Hits	279	Target Neighborhood Hits	586	Shared Neighborhood Hits	104
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

SMC2_HUMAN
θ value	8.99809 (rank : 276)	NC score	0.055807 (rank : 201)
Query Neighborhood Hits	279	Target Neighborhood Hits	1405	Shared Neighborhood Hits	132
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

SPRL1_MOUSE
θ value	8.99809 (rank : 277)	NC score	0.086378 (rank : 90)
Query Neighborhood Hits	279	Target Neighborhood Hits	403	Shared Neighborhood Hits	87
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

SRCH_HUMAN
θ value	8.99809 (rank : 278)	NC score	0.044403 (rank : 290)
Query Neighborhood Hits	279	Target Neighborhood Hits	225	Shared Neighborhood Hits	34
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

TNF13_HUMAN
θ value	8.99809 (rank : 279)	NC score	0.010878 (rank : 384)
Query Neighborhood Hits	279	Target Neighborhood Hits	17	Shared Neighborhood Hits	5
SwissProt Accessions	O75888, Q96HV6, Q9P1M8, Q9P1M9	Gene names	TNFSF13, APRIL, TALL2, ZTNF2
Domain Architecture
Description	Tumor necrosis factor ligand superfamily member 13 precursor (A proliferation-inducing ligand) (APRIL) (TNF- and APOL-related leukocyte expressed ligand 2) (TALL-2) (TNF-related death ligand 1) (TRDL-1) (CD256 antigen).

ABTAP_HUMAN
θ value	θ > 10 (rank : 280)	NC score	0.073920 (rank : 121)
Query Neighborhood Hits	279	Target Neighborhood Hits	290	Shared Neighborhood Hits	60
SwissProt Accessions	Q9H501, Q86X92, Q9H9Q5, Q9HA35, Q9NX93, Q9P1S6	Gene names	ABTAP, C20orf6
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

ABTB2_HUMAN
θ value	θ > 10 (rank : 281)	NC score	0.062032 (rank : 162)
Query Neighborhood Hits	279	Target Neighborhood Hits	391	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N961, Q6MZW4, Q8NB44	Gene names	ABTB2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ABTB2_MOUSE
θ value	θ > 10 (rank : 282)	NC score	0.061757 (rank : 165)
Query Neighborhood Hits	279	Target Neighborhood Hits	414	Shared Neighborhood Hits	9
SwissProt Accessions	Q7TQI7	Gene names	Abtb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ACINU_HUMAN
θ value	θ > 10 (rank : 283)	NC score	0.065808 (rank : 147)
Query Neighborhood Hits	279	Target Neighborhood Hits	828	Shared Neighborhood Hits	114
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

AKA12_HUMAN
θ value	θ > 10 (rank : 284)	NC score	0.116697 (rank : 49)
Query Neighborhood Hits	279	Target Neighborhood Hits	825	Shared Neighborhood Hits	141
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

BTBD2_HUMAN
θ value	θ > 10 (rank : 285)	NC score	0.054587 (rank : 213)
Query Neighborhood Hits	279	Target Neighborhood Hits	161	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BX70, O60418, O75248, Q7Z5W0, Q96SX8, Q9NPS1, Q9NX81	Gene names	BTBD2
Domain Architecture
Description	BTB/POZ domain-containing protein 2.

BTBD3_HUMAN
θ value	θ > 10 (rank : 286)	NC score	0.055664 (rank : 203)
Query Neighborhood Hits	279	Target Neighborhood Hits	127	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y2F9	Gene names	BTBD3, KIAA0952
Domain Architecture
Description	BTB/POZ domain-containing protein 3.

BTBD3_MOUSE
θ value	θ > 10 (rank : 287)	NC score	0.056204 (rank : 200)
Query Neighborhood Hits	279	Target Neighborhood Hits	124	Shared Neighborhood Hits	6
SwissProt Accessions	P58545	Gene names	Btbd3
Domain Architecture
Description	BTB/POZ domain-containing protein 3.

BTBD6_MOUSE
θ value	θ > 10 (rank : 288)	NC score	0.050445 (rank : 259)
Query Neighborhood Hits	279	Target Neighborhood Hits	125	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K2J9	Gene names	Btbd6
Domain Architecture
Description	BTB/POZ domain-containing protein 6.

BTBD8_HUMAN
θ value	θ > 10 (rank : 289)	NC score	0.064645 (rank : 152)
Query Neighborhood Hits	279	Target Neighborhood Hits	146	Shared Neighborhood Hits	4
SwissProt Accessions	Q5XKL5, Q6V9S5	Gene names	BTBD8
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 8.

BTBDC_HUMAN
θ value	θ > 10 (rank : 290)	NC score	0.071291 (rank : 129)
Query Neighborhood Hits	279	Target Neighborhood Hits	248	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

C8AP2_HUMAN
θ value	θ > 10 (rank : 291)	NC score	0.053832 (rank : 220)
Query Neighborhood Hits	279	Target Neighborhood Hits	548	Shared Neighborhood Hits	96
SwissProt Accessions	Q9UKL3, Q6PH76, Q7LCQ7, Q86YD9, Q9NUQ4, Q9NZV9, Q9P2N1, Q9Y563	Gene names	CASP8AP2, FLASH, KIAA1315, RIP25
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

CCD21_HUMAN
θ value	θ > 10 (rank : 292)	NC score	0.055383 (rank : 205)
Query Neighborhood Hits	279	Target Neighborhood Hits	1228	Shared Neighborhood Hits	113
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CCD41_HUMAN
θ value	θ > 10 (rank : 293)	NC score	0.051030 (rank : 252)
Query Neighborhood Hits	279	Target Neighborhood Hits	1139	Shared Neighborhood Hits	97
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

CCD41_MOUSE
θ value	θ > 10 (rank : 294)	NC score	0.053410 (rank : 224)
Query Neighborhood Hits	279	Target Neighborhood Hits	1399	Shared Neighborhood Hits	118
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

CCD55_MOUSE
θ value	θ > 10 (rank : 295)	NC score	0.054984 (rank : 211)
Query Neighborhood Hits	279	Target Neighborhood Hits	519	Shared Neighborhood Hits	79
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

CCD91_HUMAN
θ value	θ > 10 (rank : 296)	NC score	0.056504 (rank : 195)
Query Neighborhood Hits	279	Target Neighborhood Hits	868	Shared Neighborhood Hits	95
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

CENPF_HUMAN
θ value	θ > 10 (rank : 297)	NC score	0.051946 (rank : 241)
Query Neighborhood Hits	279	Target Neighborhood Hits	1932	Shared Neighborhood Hits	128
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CEP35_HUMAN
θ value	θ > 10 (rank : 298)	NC score	0.057345 (rank : 190)
Query Neighborhood Hits	279	Target Neighborhood Hits	811	Shared Neighborhood Hits	108
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

CF060_HUMAN
θ value	θ > 10 (rank : 299)	NC score	0.054526 (rank : 214)
Query Neighborhood Hits	279	Target Neighborhood Hits	1270	Shared Neighborhood Hits	111
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

CI039_HUMAN
θ value	θ > 10 (rank : 300)	NC score	0.057650 (rank : 186)
Query Neighborhood Hits	279	Target Neighborhood Hits	1171	Shared Neighborhood Hits	119
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

CI093_HUMAN
θ value	θ > 10 (rank : 301)	NC score	0.051514 (rank : 245)
Query Neighborhood Hits	279	Target Neighborhood Hits	1088	Shared Neighborhood Hits	93
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

CK5P2_HUMAN
θ value	θ > 10 (rank : 302)	NC score	0.057377 (rank : 189)
Query Neighborhood Hits	279	Target Neighborhood Hits	1433	Shared Neighborhood Hits	126
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

CK5P2_MOUSE
θ value	θ > 10 (rank : 303)	NC score	0.050530 (rank : 258)
Query Neighborhood Hits	279	Target Neighborhood Hits	1151	Shared Neighborhood Hits	106
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

CT2NL_HUMAN
θ value	θ > 10 (rank : 304)	NC score	0.051396 (rank : 248)
Query Neighborhood Hits	279	Target Neighborhood Hits	1059	Shared Neighborhood Hits	115
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

CUL7_HUMAN
θ value	θ > 10 (rank : 305)	NC score	0.051433 (rank : 247)
Query Neighborhood Hits	279	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q14999, Q5T654	Gene names	CUL7, KIAA0076
Domain Architecture
Description	Cullin-7 (CUL-7).

DCDC2_MOUSE
θ value	θ > 10 (rank : 306)	NC score	0.054009 (rank : 218)
Query Neighborhood Hits	279	Target Neighborhood Hits	247	Shared Neighborhood Hits	68
SwissProt Accessions	Q5DU00, Q5SZU0, Q80Y99	Gene names	Dcdc2, Kiaa1154
Domain Architecture	No domain graphic available
Description	Doublecortin domain-containing protein 2.

DMN_HUMAN
θ value	θ > 10 (rank : 307)	NC score	0.051760 (rank : 242)
Query Neighborhood Hits	279	Target Neighborhood Hits	690	Shared Neighborhood Hits	88
SwissProt Accessions	O15061	Gene names	DMN, KIAA0353
Domain Architecture
Description	Desmuslin.

EDD1_HUMAN
θ value	θ > 10 (rank : 308)	NC score	0.085166 (rank : 94)
Query Neighborhood Hits	279	Target Neighborhood Hits	170	Shared Neighborhood Hits	23
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

EDD1_MOUSE
θ value	θ > 10 (rank : 309)	NC score	0.084711 (rank : 96)
Query Neighborhood Hits	279	Target Neighborhood Hits	167	Shared Neighborhood Hits	24
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

ELOA1_HUMAN
θ value	θ > 10 (rank : 310)	NC score	0.063911 (rank : 155)
Query Neighborhood Hits	279	Target Neighborhood Hits	388	Shared Neighborhood Hits	69
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

ESCO1_HUMAN
θ value	θ > 10 (rank : 311)	NC score	0.052207 (rank : 238)
Query Neighborhood Hits	279	Target Neighborhood Hits	361	Shared Neighborhood Hits	86
SwissProt Accessions	Q5FWF5, Q69YG4, Q69YS3, Q6IMD7, Q8N3Z5, Q8NBG2, Q96PX7	Gene names	ESCO1, EFO1, KIAA1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1) (Establishment factor- like protein 1) (EFO1p) (hEFO1) (CTF7 homolog 1).

FA21C_HUMAN
θ value	θ > 10 (rank : 312)	NC score	0.051605 (rank : 243)
Query Neighborhood Hits	279	Target Neighborhood Hits	194	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y4E1, Q5SQU4, Q5SQU5, Q7L521, Q9UG79	Gene names	FAM21C, KIAA0592
Domain Architecture	No domain graphic available
Description	Protein FAM21C.

FA44A_HUMAN
θ value	θ > 10 (rank : 313)	NC score	0.051583 (rank : 244)
Query Neighborhood Hits	279	Target Neighborhood Hits	280	Shared Neighborhood Hits	58
SwissProt Accessions	Q8NFC6, Q6P0M8	Gene names	FAM44A
Domain Architecture	No domain graphic available
Description	Protein FAM44A.

GCC2_MOUSE
θ value	θ > 10 (rank : 314)	NC score	0.050140 (rank : 262)
Query Neighborhood Hits	279	Target Neighborhood Hits	1619	Shared Neighborhood Hits	121
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

GP73_MOUSE
θ value	θ > 10 (rank : 315)	NC score	0.053516 (rank : 221)
Query Neighborhood Hits	279	Target Neighborhood Hits	506	Shared Neighborhood Hits	79
SwissProt Accessions	Q91XA2	Gene names	Golph2
Domain Architecture	No domain graphic available
Description	Golgi phosphoprotein 2 (Golgi membrane protein GP73).

HECD1_HUMAN
θ value	θ > 10 (rank : 316)	NC score	0.072009 (rank : 126)
Query Neighborhood Hits	279	Target Neighborhood Hits	371	Shared Neighborhood Hits	15
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

HECD2_HUMAN
θ value	θ > 10 (rank : 317)	NC score	0.111671 (rank : 54)
Query Neighborhood Hits	279	Target Neighborhood Hits	41	Shared Neighborhood Hits	6
SwissProt Accessions	Q5U5R9, Q5VZ97, Q5VZ99, Q8TCP5	Gene names	HECTD2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

HECD2_MOUSE
θ value	θ > 10 (rank : 318)	NC score	0.110472 (rank : 55)
Query Neighborhood Hits	279	Target Neighborhood Hits	38	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CDU6, Q8CBQ9	Gene names	Hectd2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

HECD3_HUMAN
θ value	θ > 10 (rank : 319)	NC score	0.119753 (rank : 46)
Query Neighborhood Hits	279	Target Neighborhood Hits	49	Shared Neighborhood Hits	8
SwissProt Accessions	Q5T447, Q5T448, Q9H783	Gene names	HECTD3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

HECD3_MOUSE
θ value	θ > 10 (rank : 320)	NC score	0.119775 (rank : 45)
Query Neighborhood Hits	279	Target Neighborhood Hits	47	Shared Neighborhood Hits	8
SwissProt Accessions	Q3U487, Q3TN76, Q641P3, Q8BQ74, Q8R1L6	Gene names	Hectd3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

IF3A_MOUSE
θ value	θ > 10 (rank : 321)	NC score	0.050060 (rank : 263)
Query Neighborhood Hits	279	Target Neighborhood Hits	871	Shared Neighborhood Hits	78
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

IFT74_HUMAN
θ value	θ > 10 (rank : 322)	NC score	0.053476 (rank : 223)
Query Neighborhood Hits	279	Target Neighborhood Hits	949	Shared Neighborhood Hits	80
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

ITCH_HUMAN
θ value	θ > 10 (rank : 323)	NC score	0.085780 (rank : 92)
Query Neighborhood Hits	279	Target Neighborhood Hits	162	Shared Neighborhood Hits	6
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

ITCH_MOUSE
θ value	θ > 10 (rank : 324)	NC score	0.086597 (rank : 88)
Query Neighborhood Hits	279	Target Neighborhood Hits	127	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C863, O54971	Gene names	Itch
Domain Architecture
Description	Itchy E3 ubiquitin protein ligase (EC 6.3.2.-).

K0317_HUMAN
θ value	θ > 10 (rank : 325)	NC score	0.077919 (rank : 111)
Query Neighborhood Hits	279	Target Neighborhood Hits	46	Shared Neighborhood Hits	6
SwissProt Accessions	O15033, Q7LDY1, Q8IYY9	Gene names	KIAA0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

K0317_MOUSE
θ value	θ > 10 (rank : 326)	NC score	0.077968 (rank : 110)
Query Neighborhood Hits	279	Target Neighborhood Hits	43	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CHG5, Q6P9Q1, Q80YC4, Q8C5W5	Gene names	Kiaa0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

KMHN1_MOUSE
θ value	θ > 10 (rank : 327)	NC score	0.053872 (rank : 219)
Query Neighborhood Hits	279	Target Neighborhood Hits	949	Shared Neighborhood Hits	87
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

LRRF1_MOUSE
θ value	θ > 10 (rank : 328)	NC score	0.071952 (rank : 128)
Query Neighborhood Hits	279	Target Neighborhood Hits	440	Shared Neighborhood Hits	83
SwissProt Accessions	Q3UZ39, O70323, Q3TS94	Gene names	Lrrfip1, Flap
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (FLI-LRR-associated protein 1) (Flap-1) (H186 FLAP).

LUZP1_MOUSE
θ value	θ > 10 (rank : 329)	NC score	0.052570 (rank : 233)
Query Neighborhood Hits	279	Target Neighborhood Hits	940	Shared Neighborhood Hits	98
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

LZTR1_HUMAN
θ value	θ > 10 (rank : 330)	NC score	0.060485 (rank : 172)
Query Neighborhood Hits	279	Target Neighborhood Hits	196	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N653, Q14776	Gene names	LZTR1, TCFL2
Domain Architecture
Description	Leucine-zipper-like transcriptional regulator 1 (LZTR-1).

LZTR1_MOUSE
θ value	θ > 10 (rank : 331)	NC score	0.060354 (rank : 173)
Query Neighborhood Hits	279	Target Neighborhood Hits	200	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CQ33	Gene names	Lztr1, Tcfl2
Domain Architecture
Description	Leucine-zipper-like transcriptional regulator 1 (LZTR-1).

MATR3_MOUSE
θ value	θ > 10 (rank : 332)	NC score	0.055207 (rank : 208)
Query Neighborhood Hits	279	Target Neighborhood Hits	321	Shared Neighborhood Hits	82
SwissProt Accessions	Q8K310	Gene names	Matr3
Domain Architecture	No domain graphic available
Description	Matrin-3.

MINT_HUMAN
θ value	θ > 10 (rank : 333)	NC score	0.070373 (rank : 133)
Query Neighborhood Hits	279	Target Neighborhood Hits	1291	Shared Neighborhood Hits	108
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MY18A_MOUSE
θ value	θ > 10 (rank : 334)	NC score	0.053255 (rank : 226)
Query Neighborhood Hits	279	Target Neighborhood Hits	1989	Shared Neighborhood Hits	158
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

NED4L_HUMAN
θ value	θ > 10 (rank : 335)	NC score	0.083934 (rank : 98)
Query Neighborhood Hits	279	Target Neighborhood Hits	238	Shared Neighborhood Hits	11
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

NED4L_MOUSE
θ value	θ > 10 (rank : 336)	NC score	0.084042 (rank : 97)
Query Neighborhood Hits	279	Target Neighborhood Hits	231	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CFI0, Q8BRT9, Q8BS42, Q99PK2	Gene names	Nedd4l, Kiaa0439, Nedd4b
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

NEDD4_HUMAN
θ value	θ > 10 (rank : 337)	NC score	0.081620 (rank : 103)
Query Neighborhood Hits	279	Target Neighborhood Hits	214	Shared Neighborhood Hits	9
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).

NEDD4_MOUSE
θ value	θ > 10 (rank : 338)	NC score	0.083620 (rank : 100)
Query Neighborhood Hits	279	Target Neighborhood Hits	212	Shared Neighborhood Hits	9
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

NFH_MOUSE
θ value	θ > 10 (rank : 339)	NC score	0.051474 (rank : 246)
Query Neighborhood Hits	279	Target Neighborhood Hits	2247	Shared Neighborhood Hits	135
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

NIPBL_HUMAN
θ value	θ > 10 (rank : 340)	NC score	0.114293 (rank : 50)
Query Neighborhood Hits	279	Target Neighborhood Hits	1311	Shared Neighborhood Hits	155
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

NOLC1_HUMAN
θ value	θ > 10 (rank : 341)	NC score	0.055368 (rank : 206)
Query Neighborhood Hits	279	Target Neighborhood Hits	452	Shared Neighborhood Hits	45
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

NOP14_HUMAN
θ value	θ > 10 (rank : 342)	NC score	0.073774 (rank : 122)
Query Neighborhood Hits	279	Target Neighborhood Hits	573	Shared Neighborhood Hits	103
SwissProt Accessions	P78316, Q7LGI5, Q7Z6K0, Q8TBR6	Gene names	NOP14, C4orf9
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

NPBL_MOUSE
θ value	θ > 10 (rank : 343)	NC score	0.091215 (rank : 78)
Query Neighborhood Hits	279	Target Neighborhood Hits	1041	Shared Neighborhood Hits	127
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

NUCKS_HUMAN
θ value	θ > 10 (rank : 344)	NC score	0.055748 (rank : 202)
Query Neighborhood Hits	279	Target Neighborhood Hits	143	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H1E3, Q9H1D6, Q9H723	Gene names	NUCKS1, NUCKS
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (P1).

NUCKS_MOUSE
θ value	θ > 10 (rank : 345)	NC score	0.052140 (rank : 240)
Query Neighborhood Hits	279	Target Neighborhood Hits	114	Shared Neighborhood Hits	26
SwissProt Accessions	Q80XU3, Q8BVD8	Gene names	Nucks1, Nucks
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (JC7).

OXR1_MOUSE
θ value	θ > 10 (rank : 346)	NC score	0.094616 (rank : 75)
Query Neighborhood Hits	279	Target Neighborhood Hits	516	Shared Neighborhood Hits	103
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

PHF20_HUMAN
θ value	θ > 10 (rank : 347)	NC score	0.054462 (rank : 216)
Query Neighborhood Hits	279	Target Neighborhood Hits	394	Shared Neighborhood Hits	83
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

PHF20_MOUSE
θ value	θ > 10 (rank : 348)	NC score	0.080867 (rank : 104)
Query Neighborhood Hits	279	Target Neighborhood Hits	513	Shared Neighborhood Hits	91
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

PININ_HUMAN
θ value	θ > 10 (rank : 349)	NC score	0.053102 (rank : 227)
Query Neighborhood Hits	279	Target Neighborhood Hits	753	Shared Neighborhood Hits	88
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

PININ_MOUSE
θ value	θ > 10 (rank : 350)	NC score	0.050875 (rank : 253)
Query Neighborhood Hits	279	Target Neighborhood Hits	777	Shared Neighborhood Hits	92
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

PRP40_MOUSE
θ value	θ > 10 (rank : 351)	NC score	0.052165 (rank : 239)
Query Neighborhood Hits	279	Target Neighborhood Hits	447	Shared Neighborhood Hits	74
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

PTMA_MOUSE
θ value	θ > 10 (rank : 352)	NC score	0.056588 (rank : 194)
Query Neighborhood Hits	279	Target Neighborhood Hits	73	Shared Neighborhood Hits	17
SwissProt Accessions	P26350, Q3UQV6	Gene names	Ptma
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha].

PTMS_HUMAN
θ value	θ > 10 (rank : 353)	NC score	0.056215 (rank : 199)
Query Neighborhood Hits	279	Target Neighborhood Hits	111	Shared Neighborhood Hits	30
SwissProt Accessions	P20962	Gene names	PTMS
Domain Architecture	No domain graphic available
Description	Parathymosin.

RAD50_HUMAN
θ value	θ > 10 (rank : 354)	NC score	0.052617 (rank : 232)
Query Neighborhood Hits	279	Target Neighborhood Hits	1317	Shared Neighborhood Hits	112
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

RAD50_MOUSE
θ value	θ > 10 (rank : 355)	NC score	0.051336 (rank : 249)
Query Neighborhood Hits	279	Target Neighborhood Hits	1366	Shared Neighborhood Hits	113
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

RBM25_HUMAN
θ value	θ > 10 (rank : 356)	NC score	0.055523 (rank : 204)
Query Neighborhood Hits	279	Target Neighborhood Hits	682	Shared Neighborhood Hits	74
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

RHBT3_HUMAN
θ value	θ > 10 (rank : 357)	NC score	0.055205 (rank : 209)
Query Neighborhood Hits	279	Target Neighborhood Hits	116	Shared Neighborhood Hits	5
SwissProt Accessions	O94955, Q8IW06	Gene names	RHOBTB3, KIAA0878
Domain Architecture
Description	Rho-related BTB domain-containing protein 3.

RHBT3_MOUSE
θ value	θ > 10 (rank : 358)	NC score	0.055341 (rank : 207)
Query Neighborhood Hits	279	Target Neighborhood Hits	120	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CTN4, Q80X55, Q9CVT0	Gene names	Rhobtb3, Kiaa0878
Domain Architecture
Description	Rho-related BTB domain-containing protein 3.

RRBP1_HUMAN
θ value	θ > 10 (rank : 359)	NC score	0.069570 (rank : 138)
Query Neighborhood Hits	279	Target Neighborhood Hits	1306	Shared Neighborhood Hits	115
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

RRBP1_MOUSE
θ value	θ > 10 (rank : 360)	NC score	0.076474 (rank : 115)
Query Neighborhood Hits	279	Target Neighborhood Hits	1650	Shared Neighborhood Hits	133
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

RSF1_HUMAN
θ value	θ > 10 (rank : 361)	NC score	0.079919 (rank : 106)
Query Neighborhood Hits	279	Target Neighborhood Hits	539	Shared Neighborhood Hits	95
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

SDPR_HUMAN
θ value	θ > 10 (rank : 362)	NC score	0.052348 (rank : 237)
Query Neighborhood Hits	279	Target Neighborhood Hits	337	Shared Neighborhood Hits	73
SwissProt Accessions	O95810	Gene names	SDPR
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein) (PS-p68).

SDPR_MOUSE
θ value	θ > 10 (rank : 363)	NC score	0.061300 (rank : 167)
Query Neighborhood Hits	279	Target Neighborhood Hits	485	Shared Neighborhood Hits	99
SwissProt Accessions	Q63918, Q3V1P6, Q78EC3, Q8CBT4	Gene names	Sdpr, Sdr
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein).

SEMG2_HUMAN
θ value	θ > 10 (rank : 364)	NC score	0.050783 (rank : 255)
Query Neighborhood Hits	279	Target Neighborhood Hits	251	Shared Neighborhood Hits	56
SwissProt Accessions	Q02383, Q6X2M6	Gene names	SEMG2
Domain Architecture
Description	Semenogelin-2 precursor (Semenogelin II) (SGII).

SFR12_HUMAN
θ value	θ > 10 (rank : 365)	NC score	0.062703 (rank : 160)
Query Neighborhood Hits	279	Target Neighborhood Hits	553	Shared Neighborhood Hits	75
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

SFRIP_HUMAN
θ value	θ > 10 (rank : 366)	NC score	0.057876 (rank : 183)
Query Neighborhood Hits	279	Target Neighborhood Hits	530	Shared Neighborhood Hits	71
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

SMC1A_MOUSE
θ value	θ > 10 (rank : 367)	NC score	0.052656 (rank : 231)
Query Neighborhood Hits	279	Target Neighborhood Hits	1384	Shared Neighborhood Hits	117
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

SMUF1_HUMAN
θ value	θ > 10 (rank : 368)	NC score	0.089123 (rank : 84)
Query Neighborhood Hits	279	Target Neighborhood Hits	135	Shared Neighborhood Hits	8
SwissProt Accessions	Q9HCE7, O75853, Q9UJT8	Gene names	SMURF1, KIAA1625
Domain Architecture
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) (hSMURF1).

SMUF1_MOUSE
θ value	θ > 10 (rank : 369)	NC score	0.088727 (rank : 85)
Query Neighborhood Hits	279	Target Neighborhood Hits	142	Shared Neighborhood Hits	8
SwissProt Accessions	Q9CUN6, Q3U412, Q8K300	Gene names	Smurf1
Domain Architecture	No domain graphic available
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1).

SMUF2_HUMAN
θ value	θ > 10 (rank : 370)	NC score	0.089126 (rank : 83)
Query Neighborhood Hits	279	Target Neighborhood Hits	142	Shared Neighborhood Hits	8
SwissProt Accessions	Q9HAU4, Q9H260	Gene names	SMURF2
Domain Architecture
Description	Smad ubiquitination regulatory factor 2 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF2) (Smad-specific E3 ubiquitin ligase 2) (hSMURF2).

STK31_HUMAN
θ value	θ > 10 (rank : 371)	NC score	0.053041 (rank : 229)
Query Neighborhood Hits	279	Target Neighborhood Hits	570	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BXU1, Q9BXH8	Gene names	STK31
Domain Architecture
Description	Serine/threonine-protein kinase 31 (EC 2.7.11.1) (Serine/threonine- protein kinase NYD-SPK).

STK31_MOUSE
θ value	θ > 10 (rank : 372)	NC score	0.050860 (rank : 254)
Query Neighborhood Hits	279	Target Neighborhood Hits	474	Shared Neighborhood Hits	30
SwissProt Accessions	Q99MW1	Gene names	Stk31
Domain Architecture
Description	Serine/threonine-protein kinase 31 (EC 2.7.11.1).

SYCP1_HUMAN
θ value	θ > 10 (rank : 373)	NC score	0.060194 (rank : 174)
Query Neighborhood Hits	279	Target Neighborhood Hits	1313	Shared Neighborhood Hits	113
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

TARA_HUMAN
θ value	θ > 10 (rank : 374)	NC score	0.054512 (rank : 215)
Query Neighborhood Hits	279	Target Neighborhood Hits	1626	Shared Neighborhood Hits	105
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TAXB1_HUMAN
θ value	θ > 10 (rank : 375)	NC score	0.052445 (rank : 235)
Query Neighborhood Hits	279	Target Neighborhood Hits	829	Shared Neighborhood Hits	82
SwissProt Accessions	Q86VP1, O60398, O95770, Q13311, Q9BQG5, Q9UI88	Gene names	TAX1BP1, T6BP
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 (TRAF6-binding protein).

TCAL3_HUMAN
θ value	θ > 10 (rank : 376)	NC score	0.051148 (rank : 250)
Query Neighborhood Hits	279	Target Neighborhood Hits	274	Shared Neighborhood Hits	79
SwissProt Accessions	Q969E4	Gene names	TCEAL3
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 3 (TCEA-like protein 3) (Transcription elongation factor S-II protein-like 3).

TCAL5_HUMAN
θ value	θ > 10 (rank : 377)	NC score	0.101463 (rank : 60)
Query Neighborhood Hits	279	Target Neighborhood Hits	806	Shared Neighborhood Hits	132
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

TGON2_HUMAN
θ value	θ > 10 (rank : 378)	NC score	0.096179 (rank : 70)
Query Neighborhood Hits	279	Target Neighborhood Hits	1037	Shared Neighborhood Hits	106
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

THOC2_HUMAN
θ value	θ > 10 (rank : 379)	NC score	0.055066 (rank : 210)
Query Neighborhood Hits	279	Target Neighborhood Hits	337	Shared Neighborhood Hits	56
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

TP53B_MOUSE
θ value	θ > 10 (rank : 380)	NC score	0.064192 (rank : 153)
Query Neighborhood Hits	279	Target Neighborhood Hits	644	Shared Neighborhood Hits	82
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TR150_MOUSE
θ value	θ > 10 (rank : 381)	NC score	0.069938 (rank : 136)
Query Neighborhood Hits	279	Target Neighborhood Hits	468	Shared Neighborhood Hits	102
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

TRHY_HUMAN
θ value	θ > 10 (rank : 382)	NC score	0.053055 (rank : 228)
Query Neighborhood Hits	279	Target Neighborhood Hits	1385	Shared Neighborhood Hits	96
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

TRI44_HUMAN
θ value	θ > 10 (rank : 383)	NC score	0.052761 (rank : 230)
Query Neighborhood Hits	279	Target Neighborhood Hits	393	Shared Neighborhood Hits	46
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

TRIPC_HUMAN
θ value	θ > 10 (rank : 384)	NC score	0.099162 (rank : 66)
Query Neighborhood Hits	279	Target Neighborhood Hits	319	Shared Neighborhood Hits	28
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

TXND2_HUMAN
θ value	θ > 10 (rank : 385)	NC score	0.076720 (rank : 114)
Query Neighborhood Hits	279	Target Neighborhood Hits	793	Shared Neighborhood Hits	97
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

TXND2_MOUSE
θ value	θ > 10 (rank : 386)	NC score	0.109351 (rank : 57)
Query Neighborhood Hits	279	Target Neighborhood Hits	828	Shared Neighborhood Hits	146
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

UBE3A_HUMAN
θ value	θ > 10 (rank : 387)	NC score	0.112510 (rank : 51)
Query Neighborhood Hits	279	Target Neighborhood Hits	49	Shared Neighborhood Hits	6
SwissProt Accessions	Q05086, P78355, Q93066, Q9UEP4, Q9UEP5, Q9UEP6, Q9UEP7, Q9UEP8, Q9UEP9	Gene names	UBE3A, E6AP
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (E6AP ubiquitin-protein ligase) (Oncogenic protein-associated protein E6-AP) (Human papillomavirus E6-associated protein) (NY-REN-54 antigen).

UBE3A_MOUSE
θ value	θ > 10 (rank : 388)	NC score	0.112307 (rank : 52)
Query Neighborhood Hits	279	Target Neighborhood Hits	47	Shared Neighborhood Hits	6
SwissProt Accessions	O08759, P97482	Gene names	Ube3a
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (Oncogenic protein- associated protein E6-AP).

UBE3C_HUMAN
θ value	θ > 10 (rank : 389)	NC score	0.095276 (rank : 72)
Query Neighborhood Hits	279	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	Q15386, Q8TC15, Q96CR4, Q9UDU3	Gene names	UBE3C, KIAA0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

UBE3C_MOUSE
θ value	θ > 10 (rank : 390)	NC score	0.095027 (rank : 74)
Query Neighborhood Hits	279	Target Neighborhood Hits	48	Shared Neighborhood Hits	6
SwissProt Accessions	Q80U95, Q8BQZ6, Q8C7W6, Q8CDJ1, Q8VDL5	Gene names	Ube3c, Kiaa0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

WWP1_HUMAN
θ value	θ > 10 (rank : 391)	NC score	0.085312 (rank : 93)
Query Neighborhood Hits	279	Target Neighborhood Hits	262	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H0M0, O00307, Q96BP4	Gene names	WWP1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1) (Atropin-1-interacting protein 5) (AIP5).

WWP1_MOUSE
θ value	θ > 10 (rank : 392)	NC score	0.083741 (rank : 99)
Query Neighborhood Hits	279	Target Neighborhood Hits	138	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BZZ3, Q8BIV9, Q8VDP8	Gene names	Wwp1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1).

WWP2_HUMAN
θ value	θ > 10 (rank : 393)	NC score	0.082764 (rank : 102)
Query Neighborhood Hits	279	Target Neighborhood Hits	177	Shared Neighborhood Hits	9
SwissProt Accessions	O00308, Q96CZ2, Q9BWN6	Gene names	WWP2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2) (Atrophin-1-interacting protein 2) (AIP2).

WWP2_MOUSE
θ value	θ > 10 (rank : 394)	NC score	0.084798 (rank : 95)
Query Neighborhood Hits	279	Target Neighborhood Hits	118	Shared Neighborhood Hits	9
SwissProt Accessions	Q9DBH0, Q8BTG4, Q923F6	Gene names	Wwp2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2).

ZC313_HUMAN
θ value	θ > 10 (rank : 395)	NC score	0.069588 (rank : 137)
Query Neighborhood Hits	279	Target Neighborhood Hits	772	Shared Neighborhood Hits	107
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

Hits sorted by NC score

RPGR_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	279	Target Neighborhood Hits	279	Shared Neighborhood Hits	279
SwissProt Accessions	Q92834, O00702, O00737, Q8N5T6, Q93039, Q9HD29, Q9UMR1	Gene names	RPGR, RP3, XLRP3
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator.

RPGR_MOUSE
NC score	0.925702 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	279	Target Neighborhood Hits	281	Shared Neighborhood Hits	102
SwissProt Accessions	Q9R0X5, O88408, Q9CU92	Gene names	Rpgr
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator (mRpgr).

RCC1_HUMAN
NC score	0.805458 (rank : 3)	θ value	7.80994e-28 (rank : 5)
Query Neighborhood Hits	279	Target Neighborhood Hits	47	Shared Neighborhood Hits	37
SwissProt Accessions	P18754	Gene names	RCC1, CHC1
Domain Architecture
Description	Regulator of chromosome condensation (Chromosome condensation protein 1) (Cell cycle regulatory protein).

SRGEF_HUMAN
NC score	0.803164 (rank : 4)	θ value	8.63488e-27 (rank : 13)
Query Neighborhood Hits	279	Target Neighborhood Hits	33	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UGK8, Q9UGK9	Gene names	SERGEF, DELGEF, GNEFR
Domain Architecture	No domain graphic available
Description	Secretion-regulating guanine nucleotide exchange factor (Guanine nucleotide exchange factor-related protein) (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF).

RCC1_MOUSE
NC score	0.801750 (rank : 5)	θ value	7.80994e-28 (rank : 6)
Query Neighborhood Hits	279	Target Neighborhood Hits	45	Shared Neighborhood Hits	37
SwissProt Accessions	Q8VE37, Q3UDB6	Gene names	Rcc1, Chc1
Domain Architecture	No domain graphic available
Description	Regulator of chromosome condensation (Chromosome condensation protein 1).

SRGEF_MOUSE
NC score	0.792832 (rank : 6)	θ value	4.01107e-24 (rank : 17)
Query Neighborhood Hits	279	Target Neighborhood Hits	37	Shared Neighborhood Hits	28
SwissProt Accessions	Q80YD6, Q9QXB7	Gene names	Sergef, Delgef, Gnefr
Domain Architecture	No domain graphic available
Description	Secretion-regulating guanine nucleotide exchange factor (Guanine nucleotide exchange factor-related protein) (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF).

RCC2_MOUSE
NC score	0.777138 (rank : 7)	θ value	9.24701e-21 (rank : 19)
Query Neighborhood Hits	279	Target Neighborhood Hits	37	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BK67, Q6ZPQ0	Gene names	Rcc2, Kiaa1470
Domain Architecture	No domain graphic available
Description	Protein RCC2.

RCC2_HUMAN
NC score	0.776427 (rank : 8)	θ value	3.51386e-20 (rank : 20)
Query Neighborhood Hits	279	Target Neighborhood Hits	36	Shared Neighborhood Hits	28
SwissProt Accessions	Q9P258, Q8IVL9, Q9BSN6, Q9NPV8	Gene names	RCC2, KIAA1470, TD60
Domain Architecture	No domain graphic available
Description	Protein RCC2 (Telophase disk protein of 60 kDa) (RCC1-like protein TD- 60).

WBS16_HUMAN
NC score	0.739293 (rank : 9)	θ value	5.25075e-16 (rank : 21)
Query Neighborhood Hits	279	Target Neighborhood Hits	29	Shared Neighborhood Hits	28
SwissProt Accessions	Q96I51, Q548B1, Q9H0G7	Gene names	WBSCR16
Domain Architecture	No domain graphic available
Description	Williams-Beuren syndrome chromosome region 16 protein (RCC1-like G exchanging factor-like protein).

WBS16_MOUSE
NC score	0.733682 (rank : 10)	θ value	1.52774e-15 (rank : 22)
Query Neighborhood Hits	279	Target Neighborhood Hits	31	Shared Neighborhood Hits	28
SwissProt Accessions	Q9CYF5	Gene names	Wbscr16
Domain Architecture	No domain graphic available
Description	Williams-Beuren syndrome chromosome region 16 protein homolog.

RCBT2_HUMAN
NC score	0.677547 (rank : 11)	θ value	4.57862e-28 (rank : 4)
Query Neighborhood Hits	279	Target Neighborhood Hits	158	Shared Neighborhood Hits	28
SwissProt Accessions	O95199	Gene names	RCBTB2, CHC1L, RLG
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 2 (Regulator of chromosome condensation and BTB domain-containing protein 2) (Chromosome condensation 1-like) (CHC1-L) (RCC1-like G exchanging factor).

RCBT2_MOUSE
NC score	0.671642 (rank : 12)	θ value	2.96777e-27 (rank : 9)
Query Neighborhood Hits	279	Target Neighborhood Hits	156	Shared Neighborhood Hits	28
SwissProt Accessions	Q99LJ7, Q3TUA3, Q8BMG2	Gene names	Rcbtb2, Chc1l
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 2 (Regulator of chromosome condensation and BTB domain-containing protein 2) (Chromosome condensation 1-like).

RCBT1_HUMAN
NC score	0.649906 (rank : 13)	θ value	8.63488e-27 (rank : 12)
Query Neighborhood Hits	279	Target Neighborhood Hits	158	Shared Neighborhood Hits	28
SwissProt Accessions	Q8NDN9, Q969U9	Gene names	RCBTB1, CLLD7, E4.5
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 1 (Regulator of chromosome condensation and BTB domain-containing protein 1) (Chronic lymphocytic leukemia deletion region gene 7 protein) (CLL deletion region gene 7 protein).

RCBT1_MOUSE
NC score	0.649042 (rank : 14)	θ value	2.96777e-27 (rank : 8)
Query Neighborhood Hits	279	Target Neighborhood Hits	157	Shared Neighborhood Hits	28
SwissProt Accessions	Q6NXM2, Q8BTZ6, Q8BZV0	Gene names	Rcbtb1
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 1 (Regulator of chromosome condensation and BTB domain-containing protein 1).

HERC3_HUMAN
NC score	0.592539 (rank : 15)	θ value	1.16164e-39 (rank : 3)
Query Neighborhood Hits	279	Target Neighborhood Hits	62	Shared Neighborhood Hits	30
SwissProt Accessions	Q15034	Gene names	HERC3, KIAA0032
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain protein 3.

HERC2_HUMAN
NC score	0.575354 (rank : 16)	θ value	1.73987e-27 (rank : 7)
Query Neighborhood Hits	279	Target Neighborhood Hits	163	Shared Neighborhood Hits	35
SwissProt Accessions	O95714, Q86SV7, Q86SV8, Q86SV9, Q86YY3, Q86YY4, Q86YY5, Q86YY6, Q86YY7, Q86YY8, Q86YY9, Q86YZ0, Q86YZ1	Gene names	HERC2
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

HERC5_HUMAN
NC score	0.571802 (rank : 17)	θ value	5.06226e-27 (rank : 10)
Query Neighborhood Hits	279	Target Neighborhood Hits	66	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UII4	Gene names	HERC5, CEB1, CEBP1
Domain Architecture
Description	HECT domain and RCC1-like domain-containing protein 5 (Cyclin-E- binding protein 1).

HERC2_MOUSE
NC score	0.571323 (rank : 18)	θ value	1.12775e-26 (rank : 14)
Query Neighborhood Hits	279	Target Neighborhood Hits	167	Shared Neighborhood Hits	33
SwissProt Accessions	Q4U2R1, O88473, Q3TRJ8, Q3TS47, Q3TST2, Q3UFQ6, Q3URH7, Q5DU32, Q7TPR5, Q80VV7, Q9QYT1, Q9Z168, Q9Z171	Gene names	Herc2, jdf2, Kiaa0393, rjs
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

ALS2_HUMAN
NC score	0.526639 (rank : 19)	θ value	5.43371e-13 (rank : 24)
Query Neighborhood Hits	279	Target Neighborhood Hits	121	Shared Neighborhood Hits	31
SwissProt Accessions	Q96Q42, Q8N1E0, Q96PC4, Q96Q41, Q9H973, Q9HCK9	Gene names	ALS2, KIAA1563
Domain Architecture
Description	Alsin (Amyotrophic lateral sclerosis protein 2).

ALS2_MOUSE
NC score	0.526002 (rank : 20)	θ value	3.18553e-13 (rank : 23)
Query Neighborhood Hits	279	Target Neighborhood Hits	111	Shared Neighborhood Hits	28
SwissProt Accessions	Q920R0, Q8JZR1, Q9CXJ3	Gene names	Als2
Domain Architecture
Description	Alsin (Amyotrophic lateral sclerosis protein 2 homolog).

MYCB2_HUMAN
NC score	0.435786 (rank : 21)	θ value	1.133e-10 (rank : 25)
Query Neighborhood Hits	279	Target Neighborhood Hits	390	Shared Neighborhood Hits	53
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

MYCB2_MOUSE
NC score	0.427870 (rank : 22)	θ value	1.133e-10 (rank : 26)
Query Neighborhood Hits	279	Target Neighborhood Hits	307	Shared Neighborhood Hits	42
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

FBX24_HUMAN
NC score	0.311713 (rank : 23)	θ value	0.0193708 (rank : 52)
Query Neighborhood Hits	279	Target Neighborhood Hits	57	Shared Neighborhood Hits	28
SwissProt Accessions	O75426, Q9H0G1	Gene names	FBXO24, FBX24
Domain Architecture
Description	F-box only protein 24.

FBX24_MOUSE
NC score	0.281580 (rank : 24)	θ value	0.0113563 (rank : 47)
Query Neighborhood Hits	279	Target Neighborhood Hits	59	Shared Neighborhood Hits	28
SwissProt Accessions	Q9D417	Gene names	Fbxo24, Fbx24
Domain Architecture	No domain graphic available
Description	F-box only protein 24.

NEK9_MOUSE
NC score	0.210421 (rank : 25)	θ value	1.12775e-26 (rank : 15)
Query Neighborhood Hits	279	Target Neighborhood Hits	890	Shared Neighborhood Hits	41
SwissProt Accessions	Q8K1R7, Q8R3P1	Gene names	Nek9, Nercc
Domain Architecture
Description	Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (NimA-related protein kinase 9) (Never in mitosis A-related kinase 9).

NEK9_HUMAN
NC score	0.207819 (rank : 26)	θ value	6.61148e-27 (rank : 11)
Query Neighborhood Hits	279	Target Neighborhood Hits	900	Shared Neighborhood Hits	39
SwissProt Accessions	Q8TD19, Q52LK6, Q8NCN0, Q8TCY4, Q9UPI4, Q9Y6S4, Q9Y6S5, Q9Y6S6	Gene names	NEK9, KIAA1995, NEK8, NERCC
Domain Architecture
Description	Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (NimA-related protein kinase 9) (Never in mitosis A-related kinase 9) (Nercc1 kinase) (NIMA-related kinase 8) (Nek8).

NEK8_MOUSE
NC score	0.195900 (rank : 27)	θ value	1.5242e-23 (rank : 18)
Query Neighborhood Hits	279	Target Neighborhood Hits	872	Shared Neighborhood Hits	36
SwissProt Accessions	Q91ZR4, Q3U498, Q9D685	Gene names	Nek8, Jck
Domain Architecture
Description	Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never in mitosis A-related kinase 8) (NimA-related protein kinase 8).

NEK8_HUMAN
NC score	0.195659 (rank : 28)	θ value	4.73814e-25 (rank : 16)
Query Neighborhood Hits	279	Target Neighborhood Hits	872	Shared Neighborhood Hits	37
SwissProt Accessions	Q86SG6, Q2M1S6, Q8NDH1	Gene names	NEK8, JCK, NEK12A
Domain Architecture
Description	Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never in mitosis A-related kinase 8) (NimA-related protein kinase 8) (NIMA-related kinase 12a).

LEO1_MOUSE
NC score	0.171230 (rank : 29)	θ value	0.00869519 (rank : 42)
Query Neighborhood Hits	279	Target Neighborhood Hits	946	Shared Neighborhood Hits	151
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

LEO1_HUMAN
NC score	0.165905 (rank : 30)	θ value	0.365318 (rank : 97)
Query Neighborhood Hits	279	Target Neighborhood Hits	958	Shared Neighborhood Hits	150
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

DMP1_HUMAN
NC score	0.164356 (rank : 31)	θ value	0.00298849 (rank : 36)
Query Neighborhood Hits	279	Target Neighborhood Hits	491	Shared Neighborhood Hits	100
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

IWS1_HUMAN
NC score	0.160178 (rank : 32)	θ value	0.00102713 (rank : 33)
Query Neighborhood Hits	279	Target Neighborhood Hits	1241	Shared Neighborhood Hits	161
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

NSBP1_MOUSE
NC score	0.157807 (rank : 33)	θ value	0.0330416 (rank : 60)
Query Neighborhood Hits	279	Target Neighborhood Hits	681	Shared Neighborhood Hits	127
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

NSBP1_HUMAN
NC score	0.153676 (rank : 34)	θ value	0.000121331 (rank : 28)
Query Neighborhood Hits	279	Target Neighborhood Hits	251	Shared Neighborhood Hits	59
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

IWS1_MOUSE
NC score	0.150702 (rank : 35)	θ value	0.21417 (rank : 86)
Query Neighborhood Hits	279	Target Neighborhood Hits	1258	Shared Neighborhood Hits	153
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

DMP1_MOUSE
NC score	0.150415 (rank : 36)	θ value	0.00134147 (rank : 34)
Query Neighborhood Hits	279	Target Neighborhood Hits	498	Shared Neighborhood Hits	90
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

CYLC1_HUMAN
NC score	0.144443 (rank : 37)	θ value	9.29e-05 (rank : 27)
Query Neighborhood Hits	279	Target Neighborhood Hits	408	Shared Neighborhood Hits	74
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

DSPP_HUMAN
NC score	0.136631 (rank : 38)	θ value	0.0193708 (rank : 51)
Query Neighborhood Hits	279	Target Neighborhood Hits	645	Shared Neighborhood Hits	98
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

NASP_HUMAN
NC score	0.130315 (rank : 39)	θ value	8.99809 (rank : 269)
Query Neighborhood Hits	279	Target Neighborhood Hits	709	Shared Neighborhood Hits	136
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

DSPP_MOUSE
NC score	0.128895 (rank : 40)	θ value	0.00509761 (rank : 37)
Query Neighborhood Hits	279	Target Neighborhood Hits	491	Shared Neighborhood Hits	77
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

CYLC2_HUMAN
NC score	0.126778 (rank : 41)	θ value	0.0113563 (rank : 46)
Query Neighborhood Hits	279	Target Neighborhood Hits	223	Shared Neighborhood Hits	48
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

HTSF1_MOUSE
NC score	0.123393 (rank : 42)	θ value	0.0736092 (rank : 68)
Query Neighborhood Hits	279	Target Neighborhood Hits	425	Shared Neighborhood Hits	66
SwissProt Accessions	Q8BGC0, Q1WWK0, Q9CT41, Q9DAU3	Gene names	Htatsf1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 homolog.

ERIC1_HUMAN
NC score	0.120324 (rank : 43)	θ value	1.81305 (rank : 151)
Query Neighborhood Hits	279	Target Neighborhood Hits	364	Shared Neighborhood Hits	91
SwissProt Accessions	Q86X53, Q9P063	Gene names	ERICH1
Domain Architecture	No domain graphic available
Description	Glutamate-rich protein 1.

HUWE1_HUMAN
NC score	0.119948 (rank : 44)	θ value	0.0252991 (rank : 55)
Query Neighborhood Hits	279	Target Neighborhood Hits	443	Shared Neighborhood Hits	43
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

HECD3_MOUSE
NC score	0.119775 (rank : 45)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	279	Target Neighborhood Hits	47	Shared Neighborhood Hits	8
SwissProt Accessions	Q3U487, Q3TN76, Q641P3, Q8BQ74, Q8R1L6	Gene names	Hectd3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

HECD3_HUMAN
NC score	0.119753 (rank : 46)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	279	Target Neighborhood Hits	49	Shared Neighborhood Hits	8
SwissProt Accessions	Q5T447, Q5T448, Q9H783	Gene names	HECTD3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

HUWE1_MOUSE
NC score	0.119478 (rank : 47)	θ value	0.0252991 (rank : 56)
Query Neighborhood Hits	279	Target Neighborhood Hits	406	Shared Neighborhood Hits	38
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

MDN1_HUMAN
NC score	0.118063 (rank : 48)	θ value	0.0193708 (rank : 53)
Query Neighborhood Hits	279	Target Neighborhood Hits	662	Shared Neighborhood Hits	114
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

AKA12_HUMAN
NC score	0.116697 (rank : 49)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	279	Target Neighborhood Hits	825	Shared Neighborhood Hits	141
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

NIPBL_HUMAN
NC score	0.114293 (rank : 50)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	279	Target Neighborhood Hits	1311	Shared Neighborhood Hits	155
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

UBE3A_HUMAN
NC score	0.112510 (rank : 51)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	279	Target Neighborhood Hits	49	Shared Neighborhood Hits	6
SwissProt Accessions	Q05086, P78355, Q93066, Q9UEP4, Q9UEP5, Q9UEP6, Q9UEP7, Q9UEP8, Q9UEP9	Gene names	UBE3A, E6AP
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (E6AP ubiquitin-protein ligase) (Oncogenic protein-associated protein E6-AP) (Human papillomavirus E6-associated protein) (NY-REN-54 antigen).

UBE3A_MOUSE
NC score	0.112307 (rank : 52)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	279	Target Neighborhood Hits	47	Shared Neighborhood Hits	6
SwissProt Accessions	O08759, P97482	Gene names	Ube3a
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (Oncogenic protein- associated protein E6-AP).

MAP1B_HUMAN
NC score	0.112298 (rank : 53)	θ value	0.0330416 (rank : 59)
Query Neighborhood Hits	279	Target Neighborhood Hits	903	Shared Neighborhood Hits	108
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

HECD2_HUMAN
NC score	0.111671 (rank : 54)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	279	Target Neighborhood Hits	41	Shared Neighborhood Hits	6
SwissProt Accessions	Q5U5R9, Q5VZ97, Q5VZ99, Q8TCP5	Gene names	HECTD2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

HECD2_MOUSE
NC score	0.110472 (rank : 55)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	279	Target Neighborhood Hits	38	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CDU6, Q8CBQ9	Gene names	Hectd2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

YTDC1_HUMAN
NC score	0.110351 (rank : 56)	θ value	0.0113563 (rank : 48)
Query Neighborhood Hits	279	Target Neighborhood Hits	458	Shared Neighborhood Hits	81
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

TXND2_MOUSE
NC score	0.109351 (rank : 57)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	279	Target Neighborhood Hits	828	Shared Neighborhood Hits	146
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

ATRX_HUMAN
NC score	0.104429 (rank : 58)	θ value	0.0113563 (rank : 45)
Query Neighborhood Hits	279	Target Neighborhood Hits	842	Shared Neighborhood Hits	127
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

MAP1A_HUMAN
NC score	0.104317 (rank : 59)	θ value	0.47712 (rank : 105)
Query Neighborhood Hits	279	Target Neighborhood Hits	1626	Shared Neighborhood Hits	158
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

TCAL5_HUMAN
NC score	0.101463 (rank : 60)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	279	Target Neighborhood Hits	806	Shared Neighborhood Hits	132
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

MAP1B_MOUSE
NC score	0.101167 (rank : 61)	θ value	0.21417 (rank : 88)
Query Neighborhood Hits	279	Target Neighborhood Hits	977	Shared Neighborhood Hits	116
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

RBBP6_HUMAN
NC score	0.101049 (rank : 62)	θ value	4.03905 (rank : 202)
Query Neighborhood Hits	279	Target Neighborhood Hits	1135	Shared Neighborhood Hits	138
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

HTSF1_HUMAN
NC score	0.100814 (rank : 63)	θ value	0.279714 (rank : 92)
Query Neighborhood Hits	279	Target Neighborhood Hits	408	Shared Neighborhood Hits	63
SwissProt Accessions	O43719, Q59G06, Q99730	Gene names	HTATSF1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 (Tat-SF1).

CCAR1_MOUSE
NC score	0.099886 (rank : 64)	θ value	0.0961366 (rank : 73)
Query Neighborhood Hits	279	Target Neighborhood Hits	414	Shared Neighborhood Hits	67
SwissProt Accessions	Q8CH18, Q6AXC9, Q6PAR2, Q80XE4, Q8BJY0, Q8BVN2, Q8CGG1, Q9CSR5	Gene names	Ccar1, Carp1
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1).

RBBP6_MOUSE
NC score	0.099474 (rank : 65)	θ value	4.03905 (rank : 203)
Query Neighborhood Hits	279	Target Neighborhood Hits	1014	Shared Neighborhood Hits	127
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

TRIPC_HUMAN
NC score	0.099162 (rank : 66)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	279	Target Neighborhood Hits	319	Shared Neighborhood Hits	28
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

LRRF1_HUMAN
NC score	0.097110 (rank : 67)	θ value	0.47712 (rank : 103)
Query Neighborhood Hits	279	Target Neighborhood Hits	625	Shared Neighborhood Hits	99
SwissProt Accessions	Q32MZ4, O75766, O75799, Q32MZ5, Q53T49, Q6PKG2	Gene names	LRRFIP1, GCF2, TRIP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (TAR RNA-interacting protein) (GC-binding factor 2).

ARS2_HUMAN
NC score	0.096862 (rank : 68)	θ value	0.0193708 (rank : 49)
Query Neighborhood Hits	279	Target Neighborhood Hits	186	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BXP5, O95808, Q9BWP6, Q9BXP4	Gene names	ARS2, ASR2
Domain Architecture
Description	Arsenite-resistance protein 2.

ATRX_MOUSE
NC score	0.096819 (rank : 69)	θ value	0.0193708 (rank : 50)
Query Neighborhood Hits	279	Target Neighborhood Hits	682	Shared Neighborhood Hits	107
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

TGON2_HUMAN
NC score	0.096179 (rank : 70)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	279	Target Neighborhood Hits	1037	Shared Neighborhood Hits	106
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

CF010_HUMAN
NC score	0.095528 (rank : 71)	θ value	5.27518 (rank : 209)
Query Neighborhood Hits	279	Target Neighborhood Hits	329	Shared Neighborhood Hits	79
SwissProt Accessions	Q5SRN2, Q5SPI9, Q5SPJ0, Q5SPK9, Q5SPL0, Q5SRN3, Q5TG25, Q5TG26, Q8N4B6	Gene names	C6orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf10.

UBE3C_HUMAN
NC score	0.095276 (rank : 72)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	279	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	Q15386, Q8TC15, Q96CR4, Q9UDU3	Gene names	UBE3C, KIAA0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

PTMA_HUMAN
NC score	0.095061 (rank : 73)	θ value	2.36792 (rank : 174)
Query Neighborhood Hits	279	Target Neighborhood Hits	88	Shared Neighborhood Hits	23
SwissProt Accessions	P06454, Q15249, Q15592	Gene names	PTMA, TMSA
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha-1].

UBE3C_MOUSE
NC score	0.095027 (rank : 74)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	279	Target Neighborhood Hits	48	Shared Neighborhood Hits	6
SwissProt Accessions	Q80U95, Q8BQZ6, Q8C7W6, Q8CDJ1, Q8VDL5	Gene names	Ube3c, Kiaa0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

OXR1_MOUSE
NC score	0.094616 (rank : 75)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	279	Target Neighborhood Hits	516	Shared Neighborhood Hits	103
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

SAS10_HUMAN
NC score	0.092512 (rank : 76)	θ value	0.00509761 (rank : 38)
Query Neighborhood Hits	279	Target Neighborhood Hits	102	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NQZ2, Q6FI82	Gene names	CRLZ1, SAS10
Domain Architecture	No domain graphic available
Description	Something about silencing protein 10 (Disrupter of silencing SAS10) (Charged amino acid-rich leucine zipper 1).

T2FA_HUMAN
NC score	0.091252 (rank : 77)	θ value	0.163984 (rank : 84)
Query Neighborhood Hits	279	Target Neighborhood Hits	228	Shared Neighborhood Hits	48
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

NPBL_MOUSE
NC score	0.091215 (rank : 78)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	279	Target Neighborhood Hits	1041	Shared Neighborhood Hits	127
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

IF2P_HUMAN
NC score	0.090752 (rank : 79)	θ value	1.38821 (rank : 144)
Query Neighborhood Hits	279	Target Neighborhood Hits	889	Shared Neighborhood Hits	98
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

CCAR1_HUMAN
NC score	0.090181 (rank : 80)	θ value	0.0563607 (rank : 65)
Query Neighborhood Hits	279	Target Neighborhood Hits	444	Shared Neighborhood Hits	72
SwissProt Accessions	Q8IX12, Q32NE3, Q5VUP6, Q6PIZ0, Q6X935, Q9H8N4, Q9NVA7, Q9NVQ0, Q9NWM6	Gene names	CCAR1, CARP1, DIS
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1) (Death inducer with SAP domain).

ABTAP_MOUSE
NC score	0.089652 (rank : 81)	θ value	0.47712 (rank : 99)
Query Neighborhood Hits	279	Target Neighborhood Hits	381	Shared Neighborhood Hits	66
SwissProt Accessions	Q3V1V3	Gene names	Abtap
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

MPP10_HUMAN
NC score	0.089332 (rank : 82)	θ value	0.21417 (rank : 89)
Query Neighborhood Hits	279	Target Neighborhood Hits	306	Shared Neighborhood Hits	60
SwissProt Accessions	O00566	Gene names	MPHOSPH10, MPP10
Domain Architecture
Description	U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10).

SMUF2_HUMAN
NC score	0.089126 (rank : 83)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	279	Target Neighborhood Hits	142	Shared Neighborhood Hits	8
SwissProt Accessions	Q9HAU4, Q9H260	Gene names	SMURF2
Domain Architecture
Description	Smad ubiquitination regulatory factor 2 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF2) (Smad-specific E3 ubiquitin ligase 2) (hSMURF2).

SMUF1_HUMAN
NC score	0.089123 (rank : 84)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	279	Target Neighborhood Hits	135	Shared Neighborhood Hits	8
SwissProt Accessions	Q9HCE7, O75853, Q9UJT8	Gene names	SMURF1, KIAA1625
Domain Architecture
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) (hSMURF1).

SMUF1_MOUSE
NC score	0.088727 (rank : 85)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	279	Target Neighborhood Hits	142	Shared Neighborhood Hits	8
SwissProt Accessions	Q9CUN6, Q3U412, Q8K300	Gene names	Smurf1
Domain Architecture	No domain graphic available
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1).

ARS2_MOUSE
NC score	0.088297 (rank : 86)	θ value	0.0563607 (rank : 64)
Query Neighborhood Hits	279	Target Neighborhood Hits	212	Shared Neighborhood Hits	34
SwissProt Accessions	Q99MR6, Q99MR4, Q99MR5, Q99MR7	Gene names	Ars2, Asr2
Domain Architecture
Description	Arsenite-resistance protein 2.

TRDN_HUMAN
NC score	0.088134 (rank : 87)	θ value	0.0736092 (rank : 72)
Query Neighborhood Hits	279	Target Neighborhood Hits	542	Shared Neighborhood Hits	72
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

ITCH_MOUSE
NC score	0.086597 (rank : 88)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	279	Target Neighborhood Hits	127	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C863, O54971	Gene names	Itch
Domain Architecture
Description	Itchy E3 ubiquitin protein ligase (EC 6.3.2.-).

DAXX_MOUSE
NC score	0.086427 (rank : 89)	θ value	0.00869519 (rank : 40)
Query Neighborhood Hits	279	Target Neighborhood Hits	173	Shared Neighborhood Hits	30
SwissProt Accessions	O35613, Q9QWT8, Q9QWV3	Gene names	Daxx
Domain Architecture
Description	Death domain-associated protein 6 (Daxx).

SPRL1_MOUSE
NC score	0.086378 (rank : 90)	θ value	8.99809 (rank : 277)
Query Neighborhood Hits	279	Target Neighborhood Hits	403	Shared Neighborhood Hits	87
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

CLSPN_HUMAN
NC score	0.085793 (rank : 91)	θ value	0.279714 (rank : 91)
Query Neighborhood Hits	279	Target Neighborhood Hits	433	Shared Neighborhood Hits	82
SwissProt Accessions	Q9HAW4, Q5VYG0, Q6P6H5, Q8IWI1	Gene names	CLSPN
Domain Architecture	No domain graphic available
Description	Claspin (hClaspin) (Hu-Claspin).

ITCH_HUMAN
NC score	0.085780 (rank : 92)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	279	Target Neighborhood Hits	162	Shared Neighborhood Hits	6
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

WWP1_HUMAN
NC score	0.085312 (rank : 93)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	279	Target Neighborhood Hits	262	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H0M0, O00307, Q96BP4	Gene names	WWP1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1) (Atropin-1-interacting protein 5) (AIP5).

EDD1_HUMAN
NC score	0.085166 (rank : 94)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	279	Target Neighborhood Hits	170	Shared Neighborhood Hits	23
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

WWP2_MOUSE
NC score	0.084798 (rank : 95)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	279	Target Neighborhood Hits	118	Shared Neighborhood Hits	9
SwissProt Accessions	Q9DBH0, Q8BTG4, Q923F6	Gene names	Wwp2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2).

EDD1_MOUSE
NC score	0.084711 (rank : 96)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	279	Target Neighborhood Hits	167	Shared Neighborhood Hits	24
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

NED4L_MOUSE
NC score	0.084042 (rank : 97)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	279	Target Neighborhood Hits	231	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CFI0, Q8BRT9, Q8BS42, Q99PK2	Gene names	Nedd4l, Kiaa0439, Nedd4b
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

NED4L_HUMAN
NC score	0.083934 (rank : 98)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	279	Target Neighborhood Hits	238	Shared Neighborhood Hits	11
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

WWP1_MOUSE
NC score	0.083741 (rank : 99)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	279	Target Neighborhood Hits	138	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BZZ3, Q8BIV9, Q8VDP8	Gene names	Wwp1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1).

NEDD4_MOUSE
NC score	0.083620 (rank : 100)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	279	Target Neighborhood Hits	212	Shared Neighborhood Hits	9
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

OXR1_HUMAN
NC score	0.083614 (rank : 101)	θ value	0.163984 (rank : 82)
Query Neighborhood Hits	279	Target Neighborhood Hits	282	Shared Neighborhood Hits	72
SwissProt Accessions	Q8N573, Q3LIB5, Q6ZVK9, Q8N8V0, Q9H266, Q9NWC7	Gene names	OXR1
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1.

WWP2_HUMAN
NC score	0.082764 (rank : 102)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	279	Target Neighborhood Hits	177	Shared Neighborhood Hits	9
SwissProt Accessions	O00308, Q96CZ2, Q9BWN6	Gene names	WWP2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2) (Atrophin-1-interacting protein 2) (AIP2).

NEDD4_HUMAN
NC score	0.081620 (rank : 103)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	279	Target Neighborhood Hits	214	Shared Neighborhood Hits	9
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).

PHF20_MOUSE
NC score	0.080867 (rank : 104)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	279	Target Neighborhood Hits	513	Shared Neighborhood Hits	91
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

CALD1_HUMAN
NC score	0.080454 (rank : 105)	θ value	0.0330416 (rank : 57)
Query Neighborhood Hits	279	Target Neighborhood Hits	959	Shared Neighborhood Hits	91
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

RSF1_HUMAN
NC score	0.079919 (rank : 106)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	279	Target Neighborhood Hits	539	Shared Neighborhood Hits	95
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

GOGB1_HUMAN
NC score	0.078647 (rank : 107)	θ value	0.000270298 (rank : 29)
Query Neighborhood Hits	279	Target Neighborhood Hits	2297	Shared Neighborhood Hits	160
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

SAS10_MOUSE
NC score	0.078341 (rank : 108)	θ value	0.163984 (rank : 83)
Query Neighborhood Hits	279	Target Neighborhood Hits	81	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JI13, Q3UL95, Q8R5C6, Q9JJ12	Gene names	Crlz1, Crl1, Sas10
Domain Architecture	No domain graphic available
Description	Something about silencing protein 10 (Disrupter of silencing SAS10) (Charged amino acid-rich leucine zipper 1) (Crl-1).

HIRP3_HUMAN
NC score	0.078076 (rank : 109)	θ value	1.81305 (rank : 153)
Query Neighborhood Hits	279	Target Neighborhood Hits	323	Shared Neighborhood Hits	61
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

K0317_MOUSE
NC score	0.077968 (rank : 110)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	279	Target Neighborhood Hits	43	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CHG5, Q6P9Q1, Q80YC4, Q8C5W5	Gene names	Kiaa0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

K0317_HUMAN
NC score	0.077919 (rank : 111)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	279	Target Neighborhood Hits	46	Shared Neighborhood Hits	6
SwissProt Accessions	O15033, Q7LDY1, Q8IYY9	Gene names	KIAA0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

SIAL_HUMAN
NC score	0.077735 (rank : 112)	θ value	0.0330416 (rank : 62)
Query Neighborhood Hits	279	Target Neighborhood Hits	77	Shared Neighborhood Hits	20
SwissProt Accessions	P21815	Gene names	IBSP, BNSP
Domain Architecture
Description	Bone sialoprotein-2 precursor (Bone sialoprotein II) (BSP II) (Cell- binding sialoprotein) (Integrin-binding sialoprotein).

SYCP2_HUMAN
NC score	0.077229 (rank : 113)	θ value	0.62314 (rank : 113)
Query Neighborhood Hits	279	Target Neighborhood Hits	230	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BX26, O75763, Q5JX11, Q9NTX8, Q9UG27	Gene names	SYCP2, SCP2
Domain Architecture	No domain graphic available
Description	Synaptonemal complex protein 2 (SCP-2) (Synaptonemal complex lateral element protein) (hsSCP2).

TXND2_HUMAN
NC score	0.076720 (rank : 114)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	279	Target Neighborhood Hits	793	Shared Neighborhood Hits	97
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

RRBP1_MOUSE
NC score	0.076474 (rank : 115)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	279	Target Neighborhood Hits	1650	Shared Neighborhood Hits	133
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

CCD46_MOUSE
NC score	0.076413 (rank : 116)	θ value	0.00228821 (rank : 35)
Query Neighborhood Hits	279	Target Neighborhood Hits	1405	Shared Neighborhood Hits	130
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

RPGR1_MOUSE
NC score	0.075607 (rank : 117)	θ value	0.813845 (rank : 124)
Query Neighborhood Hits	279	Target Neighborhood Hits	713	Shared Neighborhood Hits	90
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

MFAP1_HUMAN
NC score	0.075166 (rank : 118)	θ value	5.27518 (rank : 218)
Query Neighborhood Hits	279	Target Neighborhood Hits	321	Shared Neighborhood Hits	57
SwissProt Accessions	P55081	Gene names	MFAP1
Domain Architecture
Description	Microfibrillar-associated protein 1.

MFAP1_MOUSE
NC score	0.075120 (rank : 119)	θ value	2.36792 (rank : 167)
Query Neighborhood Hits	279	Target Neighborhood Hits	353	Shared Neighborhood Hits	54
SwissProt Accessions	Q9CQU1, Q3TU29, Q8CCL1, Q9CSJ5	Gene names	Mfap1
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 1.

RP1L1_HUMAN
NC score	0.074550 (rank : 120)	θ value	0.0563607 (rank : 67)
Query Neighborhood Hits	279	Target Neighborhood Hits	1072	Shared Neighborhood Hits	80
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

ABTAP_HUMAN
NC score	0.073920 (rank : 121)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	279	Target Neighborhood Hits	290	Shared Neighborhood Hits	60
SwissProt Accessions	Q9H501, Q86X92, Q9H9Q5, Q9HA35, Q9NX93, Q9P1S6	Gene names	ABTAP, C20orf6
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

NOP14_HUMAN
NC score	0.073774 (rank : 122)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	279	Target Neighborhood Hits	573	Shared Neighborhood Hits	103
SwissProt Accessions	P78316, Q7LGI5, Q7Z6K0, Q8TBR6	Gene names	NOP14, C4orf9
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

SYCP1_MOUSE
NC score	0.072596 (rank : 123)	θ value	0.00869519 (rank : 44)
Query Neighborhood Hits	279	Target Neighborhood Hits	1456	Shared Neighborhood Hits	123
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

PSIP1_HUMAN
NC score	0.072405 (rank : 124)	θ value	2.36792 (rank : 173)
Query Neighborhood Hits	279	Target Neighborhood Hits	341	Shared Neighborhood Hits	79
SwissProt Accessions	O75475, O00256, O95368, Q6P391, Q86YB9, Q9NZI3, Q9UER6	Gene names	PSIP1, DFS70, LEDGF, PSIP2
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (Transcriptional coactivator p75/p52) (Dense fine speckles 70 kDa protein) (DFS 70) (CLL-associated antigen KW-7).

MPP8_HUMAN
NC score	0.072377 (rank : 125)	θ value	2.36792 (rank : 168)
Query Neighborhood Hits	279	Target Neighborhood Hits	948	Shared Neighborhood Hits	125
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

HECD1_HUMAN
NC score	0.072009 (rank : 126)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	279	Target Neighborhood Hits	371	Shared Neighborhood Hits	15
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

MAP9_HUMAN
NC score	0.071959 (rank : 127)	θ value	3.0926 (rank : 183)
Query Neighborhood Hits	279	Target Neighborhood Hits	518	Shared Neighborhood Hits	78
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

LRRF1_MOUSE
NC score	0.071952 (rank : 128)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	279	Target Neighborhood Hits	440	Shared Neighborhood Hits	83
SwissProt Accessions	Q3UZ39, O70323, Q3TS94	Gene names	Lrrfip1, Flap
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (FLI-LRR-associated protein 1) (Flap-1) (H186 FLAP).

BTBDC_HUMAN
NC score	0.071291 (rank : 129)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	279	Target Neighborhood Hits	248	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

SMCE1_MOUSE
NC score	0.071257 (rank : 130)	θ value	0.365318 (rank : 98)
Query Neighborhood Hits	279	Target Neighborhood Hits	409	Shared Neighborhood Hits	84
SwissProt Accessions	O54941, Q8BPD9	Gene names	Smarce1, Baf57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator chromatin subfamily E member 1 (BRG1-associated factor 57).

SEC63_MOUSE
NC score	0.071190 (rank : 131)	θ value	3.0926 (rank : 191)
Query Neighborhood Hits	279	Target Neighborhood Hits	601	Shared Neighborhood Hits	112
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

NEST_HUMAN
NC score	0.071186 (rank : 132)	θ value	0.813845 (rank : 121)
Query Neighborhood Hits	279	Target Neighborhood Hits	1305	Shared Neighborhood Hits	125
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

MINT_HUMAN
NC score	0.070373 (rank : 133)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	279	Target Neighborhood Hits	1291	Shared Neighborhood Hits	108
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NALP5_MOUSE
NC score	0.070344 (rank : 134)	θ value	0.0961366 (rank : 75)
Query Neighborhood Hits	279	Target Neighborhood Hits	560	Shared Neighborhood Hits	116
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

MINT_MOUSE
NC score	0.070294 (rank : 135)	θ value	0.00869519 (rank : 43)
Query Neighborhood Hits	279	Target Neighborhood Hits	1514	Shared Neighborhood Hits	94
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

TR150_MOUSE
NC score	0.069938 (rank : 136)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	279	Target Neighborhood Hits	468	Shared Neighborhood Hits	102
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

ZC313_HUMAN
NC score	0.069588 (rank : 137)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	279	Target Neighborhood Hits	772	Shared Neighborhood Hits	107
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

RRBP1_HUMAN
NC score	0.069570 (rank : 138)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	279	Target Neighborhood Hits	1306	Shared Neighborhood Hits	115
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

RENT2_HUMAN
NC score	0.068928 (rank : 139)	θ value	1.81305 (rank : 160)
Query Neighborhood Hits	279	Target Neighborhood Hits	618	Shared Neighborhood Hits	74
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

ANR11_HUMAN
NC score	0.068838 (rank : 140)	θ value	0.000461057 (rank : 30)
Query Neighborhood Hits	279	Target Neighborhood Hits	1289	Shared Neighborhood Hits	119
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

KMHN1_HUMAN
NC score	0.068252 (rank : 141)	θ value	0.0330416 (rank : 58)
Query Neighborhood Hits	279	Target Neighborhood Hits	950	Shared Neighborhood Hits	93
SwissProt Accessions	Q8TBZ0, Q86YI9, Q8N7W0	Gene names	KMHN1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1.

SEC63_HUMAN
NC score	0.066932 (rank : 142)	θ value	8.99809 (rank : 275)
Query Neighborhood Hits	279	Target Neighborhood Hits	586	Shared Neighborhood Hits	104
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

NFM_MOUSE
NC score	0.066925 (rank : 143)	θ value	0.000786445 (rank : 32)
Query Neighborhood Hits	279	Target Neighborhood Hits	1159	Shared Neighborhood Hits	119
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

IFT74_MOUSE
NC score	0.066189 (rank : 144)	θ value	0.00869519 (rank : 41)
Query Neighborhood Hits	279	Target Neighborhood Hits	939	Shared Neighborhood Hits	79
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

NUF2_HUMAN
NC score	0.066153 (rank : 145)	θ value	0.125558 (rank : 80)
Query Neighborhood Hits	279	Target Neighborhood Hits	661	Shared Neighborhood Hits	67
SwissProt Accessions	Q9BZD4, Q8WU69, Q96HJ4, Q96Q78	Gene names	CDCA1, NUF2, NUF2R
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (hNuf2) (hNuf2R) (hsNuf2) (Cell division cycle-associated protein 1).

PELP1_HUMAN
NC score	0.065957 (rank : 146)	θ value	0.813845 (rank : 123)
Query Neighborhood Hits	279	Target Neighborhood Hits	596	Shared Neighborhood Hits	60
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

ACINU_HUMAN
NC score	0.065808 (rank : 147)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	279	Target Neighborhood Hits	828	Shared Neighborhood Hits	114
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

CCD46_HUMAN
NC score	0.065782 (rank : 148)	θ value	0.813845 (rank : 117)
Query Neighborhood Hits	279	Target Neighborhood Hits	1430	Shared Neighborhood Hits	116
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

AP3B1_MOUSE
NC score	0.065734 (rank : 149)	θ value	0.125558 (rank : 76)
Query Neighborhood Hits	279	Target Neighborhood Hits	302	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Z1T1, Q91YR4	Gene names	Ap3b1
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

DAXX_HUMAN
NC score	0.064938 (rank : 150)	θ value	8.99809 (rank : 263)
Query Neighborhood Hits	279	Target Neighborhood Hits	207	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UER7, O14747, O15141, O15208, Q9BWI3	Gene names	DAXX, BING2, DAP6
Domain Architecture
Description	Death domain-associated protein 6 (Daxx) (hDaxx) (Fas death domain- associated protein) (ETS1-associated protein 1) (EAP1).

MYT1L_HUMAN
NC score	0.064727 (rank : 151)	θ value	0.47712 (rank : 106)
Query Neighborhood Hits	279	Target Neighborhood Hits	471	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UL68, Q6IQ17, Q9UPP6	Gene names	MYT1L, KIAA1106
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (MyT1-L).

BTBD8_HUMAN
NC score	0.064645 (rank : 152)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	279	Target Neighborhood Hits	146	Shared Neighborhood Hits	4
SwissProt Accessions	Q5XKL5, Q6V9S5	Gene names	BTBD8
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 8.

TP53B_MOUSE
NC score	0.064192 (rank : 153)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	279	Target Neighborhood Hits	644	Shared Neighborhood Hits	82
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

LYRIC_HUMAN
NC score	0.064106 (rank : 154)	θ value	0.47712 (rank : 104)
Query Neighborhood Hits	279	Target Neighborhood Hits	99	Shared Neighborhood Hits	24
SwissProt Accessions	Q86UE4, Q6PK07, Q8TCX3	Gene names	MTDH, AEG1, LYRIC
Domain Architecture	No domain graphic available
Description	Protein LYRIC (Lysine-rich CEACAM1 co-isolated protein) (3D3/lyric) (Metastasis adhesion protein) (Metadherin) (Astrocyte elevated gene-1 protein) (AEG-1).

ELOA1_HUMAN
NC score	0.063911 (rank : 155)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	279	Target Neighborhood Hits	388	Shared Neighborhood Hits	69
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

MAP9_MOUSE
NC score	0.063779 (rank : 156)	θ value	5.27518 (rank : 217)
Query Neighborhood Hits	279	Target Neighborhood Hits	529	Shared Neighborhood Hits	79
SwissProt Accessions	Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7	Gene names	Map9, Asap
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

LYRIC_MOUSE
NC score	0.063602 (rank : 157)	θ value	0.21417 (rank : 87)
Query Neighborhood Hits	279	Target Neighborhood Hits	126	Shared Neighborhood Hits	21
SwissProt Accessions	Q80WJ7, Q3U9F8, Q3UAQ8, Q8BN67, Q8CBT9, Q8CDL0, Q8CGI7, Q9D052	Gene names	Mtdh, Lyric
Domain Architecture	No domain graphic available
Description	Protein LYRIC (Lysine-rich CEACAM1 co-isolated protein) (3D3/LYRIC) (Metastasis adhesion protein) (Metadherin).

MYST3_HUMAN
NC score	0.063310 (rank : 158)	θ value	0.0736092 (rank : 70)
Query Neighborhood Hits	279	Target Neighborhood Hits	772	Shared Neighborhood Hits	85
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

TRIPB_HUMAN
NC score	0.063185 (rank : 159)	θ value	6.88961 (rank : 249)
Query Neighborhood Hits	279	Target Neighborhood Hits	1587	Shared Neighborhood Hits	121
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

SFR12_HUMAN
NC score	0.062703 (rank : 160)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	279	Target Neighborhood Hits	553	Shared Neighborhood Hits	75
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

FA50A_MOUSE
NC score	0.062127 (rank : 161)	θ value	0.0563607 (rank : 66)
Query Neighborhood Hits	279	Target Neighborhood Hits	293	Shared Neighborhood Hits	39
SwissProt Accessions	Q9WV03, Q9D866	Gene names	Fam50a, D0HXS9928E, Xap5
Domain Architecture
Description	Protein FAM50A (XAP-5 protein).

ABTB2_HUMAN
NC score	0.062032 (rank : 162)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	279	Target Neighborhood Hits	391	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N961, Q6MZW4, Q8NB44	Gene names	ABTB2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

REST_HUMAN
NC score	0.062017 (rank : 163)	θ value	0.125558 (rank : 81)
Query Neighborhood Hits	279	Target Neighborhood Hits	1605	Shared Neighborhood Hits	128
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

IFT81_MOUSE
NC score	0.061909 (rank : 164)	θ value	0.0961366 (rank : 74)
Query Neighborhood Hits	279	Target Neighborhood Hits	959	Shared Neighborhood Hits	84
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

ABTB2_MOUSE
NC score	0.061757 (rank : 165)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	279	Target Neighborhood Hits	414	Shared Neighborhood Hits	9
SwissProt Accessions	Q7TQI7	Gene names	Abtb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

NFH_HUMAN
NC score	0.061464 (rank : 166)	θ value	0.000461057 (rank : 31)
Query Neighborhood Hits	279	Target Neighborhood Hits	1242	Shared Neighborhood Hits	108
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

SDPR_MOUSE
NC score	0.061300 (rank : 167)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	279	Target Neighborhood Hits	485	Shared Neighborhood Hits	99
SwissProt Accessions	Q63918, Q3V1P6, Q78EC3, Q8CBT4	Gene names	Sdpr, Sdr
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein).

NFM_HUMAN
NC score	0.061006 (rank : 168)	θ value	0.0736092 (rank : 71)
Query Neighborhood Hits	279	Target Neighborhood Hits	1328	Shared Neighborhood Hits	127
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

MYT1L_MOUSE
NC score	0.060995 (rank : 169)	θ value	0.279714 (rank : 93)
Query Neighborhood Hits	279	Target Neighborhood Hits	461	Shared Neighborhood Hits	68
SwissProt Accessions	P97500, O08996, Q8C643, Q8C7L4, Q8CHB4	Gene names	Myt1l, Kiaa1106, Nzf1, Png1
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (Postmitotic neural gene 1 protein) (Zinc finger protein Png-1) (Neural zinc finger factor 1) (NZF-1).

GON4L_HUMAN
NC score	0.060989 (rank : 170)	θ value	0.365318 (rank : 95)
Query Neighborhood Hits	279	Target Neighborhood Hits	555	Shared Neighborhood Hits	71
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

TPR_HUMAN
NC score	0.060878 (rank : 171)	θ value	5.27518 (rank : 224)
Query Neighborhood Hits	279	Target Neighborhood Hits	1921	Shared Neighborhood Hits	148
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

LZTR1_HUMAN
NC score	0.060485 (rank : 172)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	279	Target Neighborhood Hits	196	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N653, Q14776	Gene names	LZTR1, TCFL2
Domain Architecture
Description	Leucine-zipper-like transcriptional regulator 1 (LZTR-1).

LZTR1_MOUSE
NC score	0.060354 (rank : 173)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	279	Target Neighborhood Hits	200	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CQ33	Gene names	Lztr1, Tcfl2
Domain Architecture
Description	Leucine-zipper-like transcriptional regulator 1 (LZTR-1).

SYCP1_HUMAN
NC score	0.060194 (rank : 174)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	279	Target Neighborhood Hits	1313	Shared Neighborhood Hits	113
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

KNTC2_HUMAN
NC score	0.059691 (rank : 175)	θ value	0.125558 (rank : 78)
Query Neighborhood Hits	279	Target Neighborhood Hits	673	Shared Neighborhood Hits	55
SwissProt Accessions	O14777, Q6PJX2	Gene names	KNTC2, HEC, HEC1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (HsHec1) (Kinetochore-associated protein 2) (Highly expressed in cancer protein) (Retinoblastoma-associated protein HEC).

CENPE_HUMAN
NC score	0.059586 (rank : 176)	θ value	0.125558 (rank : 77)
Query Neighborhood Hits	279	Target Neighborhood Hits	2060	Shared Neighborhood Hits	136
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

CJ068_HUMAN
NC score	0.059421 (rank : 177)	θ value	8.99809 (rank : 260)
Query Neighborhood Hits	279	Target Neighborhood Hits	316	Shared Neighborhood Hits	59
SwissProt Accessions	Q9H943, Q8N7T7	Gene names	C10orf68
Domain Architecture	No domain graphic available
Description	Protein C10orf68.

ARI4A_HUMAN
NC score	0.058508 (rank : 178)	θ value	6.88961 (rank : 228)
Query Neighborhood Hits	279	Target Neighborhood Hits	434	Shared Neighborhood Hits	64
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

KNTC2_MOUSE
NC score	0.058230 (rank : 179)	θ value	0.365318 (rank : 96)
Query Neighborhood Hits	279	Target Neighborhood Hits	692	Shared Neighborhood Hits	53
SwissProt Accessions	Q9D0F1, Q3TQT6, Q3UWM5, Q99P70	Gene names	Kntc2, Hec1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (Kinetochore-associated protein 2).

K0586_HUMAN
NC score	0.058173 (rank : 180)	θ value	0.813845 (rank : 118)
Query Neighborhood Hits	279	Target Neighborhood Hits	311	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BVV6, O60328	Gene names	KIAA0586
Domain Architecture	No domain graphic available
Description	Protein KIAA0586.

HMMR_MOUSE
NC score	0.058075 (rank : 181)	θ value	0.47712 (rank : 102)
Query Neighborhood Hits	279	Target Neighborhood Hits	1178	Shared Neighborhood Hits	101
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

MYST4_HUMAN
NC score	0.057919 (rank : 182)	θ value	1.81305 (rank : 155)
Query Neighborhood Hits	279	Target Neighborhood Hits	671	Shared Neighborhood Hits	96
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

SFRIP_HUMAN
NC score	0.057876 (rank : 183)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	279	Target Neighborhood Hits	530	Shared Neighborhood Hits	71
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

GOGA4_HUMAN
NC score	0.057698 (rank : 184)	θ value	5.27518 (rank : 212)
Query Neighborhood Hits	279	Target Neighborhood Hits	2034	Shared Neighborhood Hits	141
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

GOGA4_MOUSE
NC score	0.057672 (rank : 185)	θ value	1.06291 (rank : 131)
Query Neighborhood Hits	279	Target Neighborhood Hits	1939	Shared Neighborhood Hits	138
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

CI039_HUMAN
NC score	0.057650 (rank : 186)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	279	Target Neighborhood Hits	1171	Shared Neighborhood Hits	119
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

ANR12_HUMAN
NC score	0.057633 (rank : 187)	θ value	0.62314 (rank : 111)
Query Neighborhood Hits	279	Target Neighborhood Hits	1081	Shared Neighborhood Hits	114
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

TP53B_HUMAN
NC score	0.057599 (rank : 188)	θ value	6.88961 (rank : 248)
Query Neighborhood Hits	279	Target Neighborhood Hits	413	Shared Neighborhood Hits	62
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

CK5P2_HUMAN
NC score	0.057377 (rank : 189)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	279	Target Neighborhood Hits	1433	Shared Neighborhood Hits	126
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

CEP35_HUMAN
NC score	0.057345 (rank : 190)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	279	Target Neighborhood Hits	811	Shared Neighborhood Hits	108
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

PSIP1_MOUSE
NC score	0.057196 (rank : 191)	θ value	3.0926 (rank : 189)
Query Neighborhood Hits	279	Target Neighborhood Hits	313	Shared Neighborhood Hits	67
SwissProt Accessions	Q99JF8, Q3TEJ7, Q3TTD7, Q3UTA1, Q80WQ7, Q99JF7, Q99LR4, Q9CT03	Gene names	Psip1, Ledgf
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (mLEDGF).

AP3B2_MOUSE
NC score	0.057003 (rank : 192)	θ value	0.813845 (rank : 116)
Query Neighborhood Hits	279	Target Neighborhood Hits	246	Shared Neighborhood Hits	47
SwissProt Accessions	Q9JME5, Q6QR53, Q8R1E5	Gene names	Ap3b2
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain).

MAP2_HUMAN
NC score	0.056700 (rank : 193)	θ value	0.0736092 (rank : 69)
Query Neighborhood Hits	279	Target Neighborhood Hits	348	Shared Neighborhood Hits	49
SwissProt Accessions	P11137, Q99975, Q99976	Gene names	MAP2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2) (MAP-2).

PTMA_MOUSE
NC score	0.056588 (rank : 194)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	279	Target Neighborhood Hits	73	Shared Neighborhood Hits	17
SwissProt Accessions	P26350, Q3UQV6	Gene names	Ptma
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha].

CCD91_HUMAN
NC score	0.056504 (rank : 195)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	279	Target Neighborhood Hits	868	Shared Neighborhood Hits	95
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

FA50A_HUMAN
NC score	0.056252 (rank : 196)	θ value	0.365318 (rank : 94)
Query Neighborhood Hits	279	Target Neighborhood Hits	264	Shared Neighborhood Hits	38
SwissProt Accessions	Q14320, Q5HY37	Gene names	FAM50A, DXS9928E, HXC26, XAP5
Domain Architecture
Description	Protein FAM50A (Protein XAP-5) (Protein HXC-26).

MY18A_HUMAN
NC score	0.056246 (rank : 197)	θ value	0.125558 (rank : 79)
Query Neighborhood Hits	279	Target Neighborhood Hits	1929	Shared Neighborhood Hits	152
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

PPIG_HUMAN
NC score	0.056217 (rank : 198)	θ value	1.38821 (rank : 147)
Query Neighborhood Hits	279	Target Neighborhood Hits	670	Shared Neighborhood Hits	111
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

PTMS_HUMAN
NC score	0.056215 (rank : 199)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	279	Target Neighborhood Hits	111	Shared Neighborhood Hits	30
SwissProt Accessions	P20962	Gene names	PTMS
Domain Architecture	No domain graphic available
Description	Parathymosin.

BTBD3_MOUSE
NC score	0.056204 (rank : 200)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	279	Target Neighborhood Hits	124	Shared Neighborhood Hits	6
SwissProt Accessions	P58545	Gene names	Btbd3
Domain Architecture
Description	BTB/POZ domain-containing protein 3.

SMC2_HUMAN
NC score	0.055807 (rank : 201)	θ value	8.99809 (rank : 276)
Query Neighborhood Hits	279	Target Neighborhood Hits	1405	Shared Neighborhood Hits	132
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

NUCKS_HUMAN
NC score	0.055748 (rank : 202)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	279	Target Neighborhood Hits	143	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H1E3, Q9H1D6, Q9H723	Gene names	NUCKS1, NUCKS
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (P1).

BTBD3_HUMAN
NC score	0.055664 (rank : 203)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	279	Target Neighborhood Hits	127	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y2F9	Gene names	BTBD3, KIAA0952
Domain Architecture
Description	BTB/POZ domain-containing protein 3.

RBM25_HUMAN
NC score	0.055523 (rank : 204)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	279	Target Neighborhood Hits	682	Shared Neighborhood Hits	74
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

CCD21_HUMAN
NC score	0.055383 (rank : 205)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	279	Target Neighborhood Hits	1228	Shared Neighborhood Hits	113
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

NOLC1_HUMAN
NC score	0.055368 (rank : 206)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	279	Target Neighborhood Hits	452	Shared Neighborhood Hits	45
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

RHBT3_MOUSE
NC score	0.055341 (rank : 207)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	279	Target Neighborhood Hits	120	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CTN4, Q80X55, Q9CVT0	Gene names	Rhobtb3, Kiaa0878
Domain Architecture
Description	Rho-related BTB domain-containing protein 3.

MATR3_MOUSE
NC score	0.055207 (rank : 208)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	279	Target Neighborhood Hits	321	Shared Neighborhood Hits	82
SwissProt Accessions	Q8K310	Gene names	Matr3
Domain Architecture	No domain graphic available
Description	Matrin-3.

RHBT3_HUMAN
NC score	0.055205 (rank : 209)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	279	Target Neighborhood Hits	116	Shared Neighborhood Hits	5
SwissProt Accessions	O94955, Q8IW06	Gene names	RHOBTB3, KIAA0878
Domain Architecture
Description	Rho-related BTB domain-containing protein 3.

THOC2_HUMAN
NC score	0.055066 (rank : 210)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	279	Target Neighborhood Hits	337	Shared Neighborhood Hits	56
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

CCD55_MOUSE
NC score	0.054984 (rank : 211)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	279	Target Neighborhood Hits	519	Shared Neighborhood Hits	79
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

AN32B_MOUSE
NC score	0.054664 (rank : 212)	θ value	0.279714 (rank : 90)
Query Neighborhood Hits	279	Target Neighborhood Hits	236	Shared Neighborhood Hits	29
SwissProt Accessions	Q9EST5	Gene names	Anp32b, Pal31
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member B (Proliferation-related acidic leucine-rich protein PAL31).

BTBD2_HUMAN
NC score	0.054587 (rank : 213)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	279	Target Neighborhood Hits	161	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BX70, O60418, O75248, Q7Z5W0, Q96SX8, Q9NPS1, Q9NX81	Gene names	BTBD2
Domain Architecture
Description	BTB/POZ domain-containing protein 2.

CF060_HUMAN
NC score	0.054526 (rank : 214)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	279	Target Neighborhood Hits	1270	Shared Neighborhood Hits	111
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

TARA_HUMAN
NC score	0.054512 (rank : 215)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	279	Target Neighborhood Hits	1626	Shared Neighborhood Hits	105
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

PHF20_HUMAN
NC score	0.054462 (rank : 216)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	279	Target Neighborhood Hits	394	Shared Neighborhood Hits	83
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

NCOA7_HUMAN
NC score	0.054037 (rank : 217)	θ value	1.81305 (rank : 156)
Query Neighborhood Hits	279	Target Neighborhood Hits	160	Shared Neighborhood Hits	38
SwissProt Accessions	Q8NI08, Q3LID6, Q4G0V1, Q5TF95, Q6IPQ4, Q6NE83, Q86T89, Q8N1W4	Gene names	NCOA7, ERAP140, ESNA1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 7 (140 kDa estrogen receptor-associated protein) (Estrogen nuclear receptor coactivator 1).

DCDC2_MOUSE
NC score	0.054009 (rank : 218)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	279	Target Neighborhood Hits	247	Shared Neighborhood Hits	68
SwissProt Accessions	Q5DU00, Q5SZU0, Q80Y99	Gene names	Dcdc2, Kiaa1154
Domain Architecture	No domain graphic available
Description	Doublecortin domain-containing protein 2.

KMHN1_MOUSE
NC score	0.053872 (rank : 219)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	279	Target Neighborhood Hits	949	Shared Neighborhood Hits	87
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

C8AP2_HUMAN
NC score	0.053832 (rank : 220)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	279	Target Neighborhood Hits	548	Shared Neighborhood Hits	96
SwissProt Accessions	Q9UKL3, Q6PH76, Q7LCQ7, Q86YD9, Q9NUQ4, Q9NZV9, Q9P2N1, Q9Y563	Gene names	CASP8AP2, FLASH, KIAA1315, RIP25
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

GP73_MOUSE
NC score	0.053516 (rank : 221)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	279	Target Neighborhood Hits	506	Shared Neighborhood Hits	79
SwissProt Accessions	Q91XA2	Gene names	Golph2
Domain Architecture	No domain graphic available
Description	Golgi phosphoprotein 2 (Golgi membrane protein GP73).

OPTN_MOUSE
NC score	0.053497 (rank : 222)	θ value	4.03905 (rank : 199)
Query Neighborhood Hits	279	Target Neighborhood Hits	1120	Shared Neighborhood Hits	101
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

IFT74_HUMAN
NC score	0.053476 (rank : 223)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	279	Target Neighborhood Hits	949	Shared Neighborhood Hits	80
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

CCD41_MOUSE
NC score	0.053410 (rank : 224)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	279	Target Neighborhood Hits	1399	Shared Neighborhood Hits	118
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

REST_MOUSE
NC score	0.053357 (rank : 225)	θ value	1.81305 (rank : 161)
Query Neighborhood Hits	279	Target Neighborhood Hits	1506	Shared Neighborhood Hits	113
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

MY18A_MOUSE
NC score	0.053255 (rank : 226)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	279	Target Neighborhood Hits	1989	Shared Neighborhood Hits	158
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

PININ_HUMAN
NC score	0.053102 (rank : 227)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	279	Target Neighborhood Hits	753	Shared Neighborhood Hits	88
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

TRHY_HUMAN
NC score	0.053055 (rank : 228)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	279	Target Neighborhood Hits	1385	Shared Neighborhood Hits	96
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

STK31_HUMAN
NC score	0.053041 (rank : 229)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	279	Target Neighborhood Hits	570	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BXU1, Q9BXH8	Gene names	STK31
Domain Architecture
Description	Serine/threonine-protein kinase 31 (EC 2.7.11.1) (Serine/threonine- protein kinase NYD-SPK).

TRI44_HUMAN
NC score	0.052761 (rank : 230)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	279	Target Neighborhood Hits	393	Shared Neighborhood Hits	46
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

SMC1A_MOUSE
NC score	0.052656 (rank : 231)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	279	Target Neighborhood Hits	1384	Shared Neighborhood Hits	117
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

RAD50_HUMAN
NC score	0.052617 (rank : 232)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	279	Target Neighborhood Hits	1317	Shared Neighborhood Hits	112
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

LUZP1_MOUSE
NC score	0.052570 (rank : 233)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	279	Target Neighborhood Hits	940	Shared Neighborhood Hits	98
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

CJ118_MOUSE
NC score	0.052478 (rank : 234)	θ value	0.47712 (rank : 101)
Query Neighborhood Hits	279	Target Neighborhood Hits	1132	Shared Neighborhood Hits	81
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

TAXB1_HUMAN
NC score	0.052445 (rank : 235)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	279	Target Neighborhood Hits	829	Shared Neighborhood Hits	82
SwissProt Accessions	Q86VP1, O60398, O95770, Q13311, Q9BQG5, Q9UI88	Gene names	TAX1BP1, T6BP
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 (TRAF6-binding protein).

PCLO_HUMAN
NC score	0.052352 (rank : 236)	θ value	0.813845 (rank : 122)
Query Neighborhood Hits	279	Target Neighborhood Hits	2046	Shared Neighborhood Hits	116
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

SDPR_HUMAN
NC score	0.052348 (rank : 237)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	279	Target Neighborhood Hits	337	Shared Neighborhood Hits	73
SwissProt Accessions	O95810	Gene names	SDPR
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein) (PS-p68).

ESCO1_HUMAN
NC score	0.052207 (rank : 238)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	279	Target Neighborhood Hits	361	Shared Neighborhood Hits	86
SwissProt Accessions	Q5FWF5, Q69YG4, Q69YS3, Q6IMD7, Q8N3Z5, Q8NBG2, Q96PX7	Gene names	ESCO1, EFO1, KIAA1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1) (Establishment factor- like protein 1) (EFO1p) (hEFO1) (CTF7 homolog 1).

PRP40_MOUSE
NC score	0.052165 (rank : 239)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	279	Target Neighborhood Hits	447	Shared Neighborhood Hits	74
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

NUCKS_MOUSE
NC score	0.052140 (rank : 240)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	279	Target Neighborhood Hits	114	Shared Neighborhood Hits	26
SwissProt Accessions	Q80XU3, Q8BVD8	Gene names	Nucks1, Nucks
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (JC7).

CENPF_HUMAN
NC score	0.051946 (rank : 241)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	279	Target Neighborhood Hits	1932	Shared Neighborhood Hits	128
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

DMN_HUMAN
NC score	0.051760 (rank : 242)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	279	Target Neighborhood Hits	690	Shared Neighborhood Hits	88
SwissProt Accessions	O15061	Gene names	DMN, KIAA0353
Domain Architecture
Description	Desmuslin.

FA21C_HUMAN
NC score	0.051605 (rank : 243)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	279	Target Neighborhood Hits	194	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y4E1, Q5SQU4, Q5SQU5, Q7L521, Q9UG79	Gene names	FAM21C, KIAA0592
Domain Architecture	No domain graphic available
Description	Protein FAM21C.

FA44A_HUMAN
NC score	0.051583 (rank : 244)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	279	Target Neighborhood Hits	280	Shared Neighborhood Hits	58
SwissProt Accessions	Q8NFC6, Q6P0M8	Gene names	FAM44A
Domain Architecture	No domain graphic available
Description	Protein FAM44A.

CI093_HUMAN
NC score	0.051514 (rank : 245)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	279	Target Neighborhood Hits	1088	Shared Neighborhood Hits	93
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

NFH_MOUSE
NC score	0.051474 (rank : 246)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	279	Target Neighborhood Hits	2247	Shared Neighborhood Hits	135
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

CUL7_HUMAN
NC score	0.051433 (rank : 247)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	279	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q14999, Q5T654	Gene names	CUL7, KIAA0076
Domain Architecture
Description	Cullin-7 (CUL-7).

CT2NL_HUMAN
NC score	0.051396 (rank : 248)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	279	Target Neighborhood Hits	1059	Shared Neighborhood Hits	115
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

RAD50_MOUSE
NC score	0.051336 (rank : 249)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	279	Target Neighborhood Hits	1366	Shared Neighborhood Hits	113
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

TCAL3_HUMAN
NC score	0.051148 (rank : 250)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	279	Target Neighborhood Hits	274	Shared Neighborhood Hits	79
SwissProt Accessions	Q969E4	Gene names	TCEAL3
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 3 (TCEA-like protein 3) (Transcription elongation factor S-II protein-like 3).

MYT1_HUMAN
NC score	0.051045 (rank : 251)	θ value	6.88961 (rank : 235)
Query Neighborhood Hits	279	Target Neighborhood Hits	475	Shared Neighborhood Hits	72
SwissProt Accessions	Q01538, O94922, Q9UPV2	Gene names	MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1
Domain Architecture
Description	Myelin transcription factor 1 (MyT1) (MyTI) (Proteolipid protein- binding protein) (PLPB1).

CCD41_HUMAN
NC score	0.051030 (rank : 252)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	279	Target Neighborhood Hits	1139	Shared Neighborhood Hits	97
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

PININ_MOUSE
NC score	0.050875 (rank : 253)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	279	Target Neighborhood Hits	777	Shared Neighborhood Hits	92
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

STK31_MOUSE
NC score	0.050860 (rank : 254)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	279	Target Neighborhood Hits	474	Shared Neighborhood Hits	30
SwissProt Accessions	Q99MW1	Gene names	Stk31
Domain Architecture
Description	Serine/threonine-protein kinase 31 (EC 2.7.11.1).

SEMG2_HUMAN
NC score	0.050783 (rank : 255)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	279	Target Neighborhood Hits	251	Shared Neighborhood Hits	56
SwissProt Accessions	Q02383, Q6X2M6	Gene names	SEMG2
Domain Architecture
Description	Semenogelin-2 precursor (Semenogelin II) (SGII).

MAPIP_MOUSE
NC score	0.050554 (rank : 256)	θ value	0.813845 (rank : 120)
Query Neighborhood Hits	279	Target Neighborhood Hits	3	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JHS3	Gene names	Mapbpip
Domain Architecture
Description	Mitogen-activated protein-binding protein-interacting protein (Late endosomal/lysosomal Mp1-interacting protein) (p14).

MAPIP_HUMAN
NC score	0.050536 (rank : 257)	θ value	0.813845 (rank : 119)
Query Neighborhood Hits	279	Target Neighborhood Hits	3	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2Q5, Q5VY99	Gene names	MAPBPIP
Domain Architecture
Description	Mitogen-activated protein-binding protein-interacting protein (Late endosomal/lysosomal Mp1-interacting protein) (p14).

CK5P2_MOUSE
NC score	0.050530 (rank : 258)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	279	Target Neighborhood Hits	1151	Shared Neighborhood Hits	106
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

BTBD6_MOUSE
NC score	0.050445 (rank : 259)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	279	Target Neighborhood Hits	125	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K2J9	Gene names	Btbd6
Domain Architecture
Description	BTB/POZ domain-containing protein 6.

TXD13_MOUSE
NC score	0.050258 (rank : 260)	θ value	0.163984 (rank : 85)
Query Neighborhood Hits	279	Target Neighborhood Hits	61	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C0L0, Q3UHC6, Q6ZPW7, Q80X49	Gene names	Txndc13, D2Bwg1356e, Kiaa1162
Domain Architecture
Description	Thioredoxin domain-containing protein 13 precursor.

AP3B1_HUMAN
NC score	0.050191 (rank : 261)	θ value	4.03905 (rank : 194)
Query Neighborhood Hits	279	Target Neighborhood Hits	283	Shared Neighborhood Hits	49
SwissProt Accessions	O00203, O00580, Q7Z393, Q9HD66	Gene names	AP3B1, ADTB3A
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

GCC2_MOUSE
NC score	0.050140 (rank : 262)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	279	Target Neighborhood Hits	1619	Shared Neighborhood Hits	121
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

IF3A_MOUSE
NC score	0.050060 (rank : 263)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	279	Target Neighborhood Hits	871	Shared Neighborhood Hits	78
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

NUCL_MOUSE
NC score	0.049558 (rank : 264)	θ value	5.27518 (rank : 222)
Query Neighborhood Hits	279	Target Neighborhood Hits	425	Shared Neighborhood Hits	38
SwissProt Accessions	P09405, Q548M9, Q61991, Q99K50	Gene names	Ncl, Nuc
Domain Architecture
Description	Nucleolin (Protein C23).

MYT1_MOUSE
NC score	0.049499 (rank : 265)	θ value	5.27518 (rank : 221)
Query Neighborhood Hits	279	Target Neighborhood Hits	385	Shared Neighborhood Hits	58
SwissProt Accessions	Q8CFC2, O08995, Q8CFH1	Gene names	Myt1, Kiaa0835, Nzf2
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1 (MyT1) (Neural zinc finger factor 2) (NZF-2).

AN32E_HUMAN
NC score	0.049313 (rank : 266)	θ value	0.47712 (rank : 100)
Query Neighborhood Hits	279	Target Neighborhood Hits	291	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BTT0, Q8N1S4, Q8WWW9	Gene names	ANP32E
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member E (LANP- like protein) (LANP-L).

NEK1_MOUSE
NC score	0.049227 (rank : 267)	θ value	3.0926 (rank : 185)
Query Neighborhood Hits	279	Target Neighborhood Hits	1311	Shared Neighborhood Hits	108
SwissProt Accessions	P51954	Gene names	Nek1
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1).

HOME2_MOUSE
NC score	0.048757 (rank : 268)	θ value	2.36792 (rank : 163)
Query Neighborhood Hits	279	Target Neighborhood Hits	882	Shared Neighborhood Hits	89
SwissProt Accessions	Q9QWW1, O89025, Q9Z0E4	Gene names	Homer2, Vesl2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up- regulated during seizure and LTP 2) (Vesl-2).

NUMA1_HUMAN
NC score	0.048744 (rank : 269)	θ value	2.36792 (rank : 170)
Query Neighborhood Hits	279	Target Neighborhood Hits	1523	Shared Neighborhood Hits	93
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

NUCL_HUMAN
NC score	0.048705 (rank : 270)	θ value	0.00665767 (rank : 39)
Query Neighborhood Hits	279	Target Neighborhood Hits	415	Shared Neighborhood Hits	34
SwissProt Accessions	P19338, Q53SK1, Q8NB06	Gene names	NCL
Domain Architecture
Description	Nucleolin (Protein C23).

ZN638_MOUSE
NC score	0.048357 (rank : 271)	θ value	1.06291 (rank : 139)
Query Neighborhood Hits	279	Target Neighborhood Hits	318	Shared Neighborhood Hits	52
SwissProt Accessions	Q61464, Q6DFV9, Q8C941	Gene names	Znf638, Np220, Zfml
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein).

BRE1A_MOUSE
NC score	0.047862 (rank : 272)	θ value	6.88961 (rank : 230)
Query Neighborhood Hits	279	Target Neighborhood Hits	1025	Shared Neighborhood Hits	81
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

EEA1_HUMAN
NC score	0.047800 (rank : 273)	θ value	5.27518 (rank : 211)
Query Neighborhood Hits	279	Target Neighborhood Hits	1796	Shared Neighborhood Hits	124
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

GOGA5_HUMAN
NC score	0.047161 (rank : 274)	θ value	6.88961 (rank : 231)
Query Neighborhood Hits	279	Target Neighborhood Hits	1168	Shared Neighborhood Hits	92
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

GON4L_MOUSE
NC score	0.046822 (rank : 275)	θ value	4.03905 (rank : 196)
Query Neighborhood Hits	279	Target Neighborhood Hits	455	Shared Neighborhood Hits	55
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

TXD13_HUMAN
NC score	0.046500 (rank : 276)	θ value	3.0926 (rank : 193)
Query Neighborhood Hits	279	Target Neighborhood Hits	106	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H1E5, Q8N4P7, Q8NCC1, Q9UJA1, Q9ULQ8	Gene names	TXNDC13, KIAA1162
Domain Architecture
Description	Thioredoxin domain-containing protein 13 precursor.

LUZP1_HUMAN
NC score	0.046472 (rank : 277)	θ value	2.36792 (rank : 166)
Query Neighborhood Hits	279	Target Neighborhood Hits	739	Shared Neighborhood Hits	63
SwissProt Accessions	Q86V48, Q5TH93, Q8N4X3, Q8TEH1	Gene names	LUZP1
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1.

GRAP1_HUMAN
NC score	0.046425 (rank : 278)	θ value	3.0926 (rank : 182)
Query Neighborhood Hits	279	Target Neighborhood Hits	944	Shared Neighborhood Hits	63
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

IF2B_MOUSE
NC score	0.046165 (rank : 279)	θ value	1.06291 (rank : 132)
Query Neighborhood Hits	279	Target Neighborhood Hits	50	Shared Neighborhood Hits	14
SwissProt Accessions	Q99L45, Q9CSH6, Q9CT12	Gene names	Eif2s2
Domain Architecture
Description	Eukaryotic translation initiation factor 2 subunit 2 (Eukaryotic translation initiation factor 2 subunit beta) (eIF-2-beta).

AN32B_HUMAN
NC score	0.046096 (rank : 280)	θ value	6.88961 (rank : 227)
Query Neighborhood Hits	279	Target Neighborhood Hits	243	Shared Neighborhood Hits	25
SwissProt Accessions	Q92688, O00655, P78458, P78459	Gene names	ANP32B, APRIL, PHAPI2
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member B (PHAPI2 protein) (Silver-stainable protein SSP29) (Acidic protein rich in leucines).

APC_HUMAN
NC score	0.045767 (rank : 281)	θ value	1.06291 (rank : 129)
Query Neighborhood Hits	279	Target Neighborhood Hits	603	Shared Neighborhood Hits	41
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

LMO7_HUMAN
NC score	0.045680 (rank : 282)	θ value	8.99809 (rank : 267)
Query Neighborhood Hits	279	Target Neighborhood Hits	507	Shared Neighborhood Hits	48
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

APC_MOUSE
NC score	0.045624 (rank : 283)	θ value	0.62314 (rank : 112)
Query Neighborhood Hits	279	Target Neighborhood Hits	441	Shared Neighborhood Hits	39
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

CROCC_MOUSE
NC score	0.045558 (rank : 284)	θ value	8.99809 (rank : 261)
Query Neighborhood Hits	279	Target Neighborhood Hits	1460	Shared Neighborhood Hits	102
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

UACA_HUMAN
NC score	0.045210 (rank : 285)	θ value	5.27518 (rank : 225)
Query Neighborhood Hits	279	Target Neighborhood Hits	1622	Shared Neighborhood Hits	112
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

SAS6_HUMAN
NC score	0.045173 (rank : 286)	θ value	8.99809 (rank : 274)
Query Neighborhood Hits	279	Target Neighborhood Hits	791	Shared Neighborhood Hits	66
SwissProt Accessions	Q6UVJ0, Q8N3K0	Gene names	SASS6, SAS6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog (HsSAS-6).

PCNT_HUMAN
NC score	0.045154 (rank : 287)	θ value	8.99809 (rank : 271)
Query Neighborhood Hits	279	Target Neighborhood Hits	1551	Shared Neighborhood Hits	102
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

ROCK1_MOUSE
NC score	0.044890 (rank : 288)	θ value	3.0926 (rank : 190)
Query Neighborhood Hits	279	Target Neighborhood Hits	2126	Shared Neighborhood Hits	111
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

RFC1_MOUSE
NC score	0.044681 (rank : 289)	θ value	2.36792 (rank : 176)
Query Neighborhood Hits	279	Target Neighborhood Hits	290	Shared Neighborhood Hits	55
SwissProt Accessions	P35601	Gene names	Rfc1, Ibf-1, Recc1
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (A1-P145) (Differentiation- specific element-binding protein) (ISRE-binding protein).

SRCH_HUMAN
NC score	0.044403 (rank : 290)	θ value	8.99809 (rank : 278)
Query Neighborhood Hits	279	Target Neighborhood Hits	225	Shared Neighborhood Hits	34
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

TPM4_HUMAN
NC score	0.044398 (rank : 291)	θ value	1.06291 (rank : 138)
Query Neighborhood Hits	279	Target Neighborhood Hits	525	Shared Neighborhood Hits	60
SwissProt Accessions	P67936, P07226, Q15659, Q9BU85, Q9H8Q3	Gene names	TPM4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4) (TM30p1).

SLK_HUMAN
NC score	0.044244 (rank : 292)	θ value	2.36792 (rank : 177)
Query Neighborhood Hits	279	Target Neighborhood Hits	1775	Shared Neighborhood Hits	123
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

ROCK1_HUMAN
NC score	0.043967 (rank : 293)	θ value	0.47712 (rank : 108)
Query Neighborhood Hits	279	Target Neighborhood Hits	2000	Shared Neighborhood Hits	104
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

SENP7_HUMAN
NC score	0.043952 (rank : 294)	θ value	1.38821 (rank : 148)
Query Neighborhood Hits	279	Target Neighborhood Hits	97	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BQF6, Q96PS5, Q9C0F6, Q9HBT5	Gene names	SENP7, KIAA1707, SSP2, SUSP2
Domain Architecture
Description	Sentrin-specific protease 7 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP7) (SUMO-1-specific protease 2).

CV106_HUMAN
NC score	0.043380 (rank : 295)	θ value	1.38821 (rank : 142)
Query Neighborhood Hits	279	Target Neighborhood Hits	125	Shared Neighborhood Hits	26
SwissProt Accessions	Q6P0N0, Q86V14, Q96PY4, Q9NUR5, Q9Y4X9	Gene names	C14orf106, KIAA1903
Domain Architecture	No domain graphic available
Description	Protein C14orf106 (P243).

PCLO_MOUSE
NC score	0.042542 (rank : 296)	θ value	0.0330416 (rank : 61)
Query Neighborhood Hits	279	Target Neighborhood Hits	2275	Shared Neighborhood Hits	105
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

IF38_HUMAN
NC score	0.042129 (rank : 297)	θ value	2.36792 (rank : 164)
Query Neighborhood Hits	279	Target Neighborhood Hits	98	Shared Neighborhood Hits	20
SwissProt Accessions	Q99613, O00215	Gene names	EIF3S8
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 8 (eIF3 p110) (eIF3c).

BAZ2B_HUMAN
NC score	0.041518 (rank : 298)	θ value	8.99809 (rank : 256)
Query Neighborhood Hits	279	Target Neighborhood Hits	803	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

PHF3_HUMAN
NC score	0.041438 (rank : 299)	θ value	3.0926 (rank : 188)
Query Neighborhood Hits	279	Target Neighborhood Hits	419	Shared Neighborhood Hits	48
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

SMCE1_HUMAN
NC score	0.041177 (rank : 300)	θ value	6.88961 (rank : 247)
Query Neighborhood Hits	279	Target Neighborhood Hits	272	Shared Neighborhood Hits	38
SwissProt Accessions	Q969G3, O43539	Gene names	SMARCE1, BAF57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 (BRG1-associated factor 57).

SLK_MOUSE
NC score	0.040615 (rank : 301)	θ value	1.06291 (rank : 137)
Query Neighborhood Hits	279	Target Neighborhood Hits	1798	Shared Neighborhood Hits	124
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

SPT6H_MOUSE
NC score	0.039745 (rank : 302)	θ value	1.38821 (rank : 149)
Query Neighborhood Hits	279	Target Neighborhood Hits	104	Shared Neighborhood Hits	22
SwissProt Accessions	Q62383, Q5SYM0, Q6GQS3, Q6ZQI0, Q8BQY6	Gene names	Supt6h, Kiaa0162
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT6.

MYH11_HUMAN
NC score	0.039360 (rank : 303)	θ value	6.88961 (rank : 234)
Query Neighborhood Hits	279	Target Neighborhood Hits	1806	Shared Neighborhood Hits	139
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

WDR60_MOUSE
NC score	0.039072 (rank : 304)	θ value	6.88961 (rank : 251)
Query Neighborhood Hits	279	Target Neighborhood Hits	344	Shared Neighborhood Hits	52
SwissProt Accessions	Q8C761, Q3UNM4	Gene names	Wdr60
Domain Architecture	No domain graphic available
Description	WD repeat protein 60.

ZCH11_HUMAN
NC score	0.039033 (rank : 305)	θ value	0.813845 (rank : 127)
Query Neighborhood Hits	279	Target Neighborhood Hits	278	Shared Neighborhood Hits	44
SwissProt Accessions	Q5TAX3, Q12764, Q5TAX4, Q86XZ3	Gene names	ZCCHC11, KIAA0191
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 11.

CIR_MOUSE
NC score	0.038610 (rank : 306)	θ value	5.27518 (rank : 210)
Query Neighborhood Hits	279	Target Neighborhood Hits	255	Shared Neighborhood Hits	35
SwissProt Accessions	Q9DA19, Q3V2N9, Q4KL44, Q52KL9, Q5FW66	Gene names	Cir
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor.

SYNE1_HUMAN
NC score	0.038163 (rank : 307)	θ value	3.0926 (rank : 192)
Query Neighborhood Hits	279	Target Neighborhood Hits	1484	Shared Neighborhood Hits	76
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

CD2L1_HUMAN
NC score	0.037488 (rank : 308)	θ value	5.27518 (rank : 208)
Query Neighborhood Hits	279	Target Neighborhood Hits	1467	Shared Neighborhood Hits	94
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

PIGT_MOUSE
NC score	0.037467 (rank : 309)	θ value	1.06291 (rank : 135)
Query Neighborhood Hits	279	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BXQ2, Q3U2X2, Q99JA3	Gene names	Pigt, Ndap7
Domain Architecture
Description	GPI transamidase component PIG-T precursor (Phosphatidylinositol- glycan biosynthesis class T protein) (Neuronal development-associated protein 7).

SPT6H_HUMAN
NC score	0.037409 (rank : 310)	θ value	4.03905 (rank : 204)
Query Neighborhood Hits	279	Target Neighborhood Hits	104	Shared Neighborhood Hits	22
SwissProt Accessions	Q7KZ85, Q15737, Q6GMQ4, Q7KYW9, Q7LDK4, Q8N526, Q92775, Q96AH3, Q9BTH9, Q9BTI2	Gene names	SUPT6H, KIAA0162, SPT6H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT6 (hSPT6) (Tat-cotransactivator 2 protein) (Tat-CT2 protein).

PIGT_HUMAN
NC score	0.037398 (rank : 311)	θ value	1.06291 (rank : 134)
Query Neighborhood Hits	279	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q969N2, Q7Z3N7, Q9BQY7, Q9BQY8, Q9UJG6, Q9Y2Z5	Gene names	PIGT
Domain Architecture
Description	GPI transamidase component PIG-T precursor (Phosphatidylinositol- glycan biosynthesis class T protein).

ANK2_HUMAN
NC score	0.037155 (rank : 312)	θ value	0.0252991 (rank : 54)
Query Neighborhood Hits	279	Target Neighborhood Hits	1615	Shared Neighborhood Hits	114
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ZCHC8_HUMAN
NC score	0.036625 (rank : 313)	θ value	0.62314 (rank : 114)
Query Neighborhood Hits	279	Target Neighborhood Hits	92	Shared Neighborhood Hits	15
SwissProt Accessions	Q6NZY4, Q7L2P6, Q8N2K5, Q96SK7, Q9NSS2, Q9NSS3	Gene names	ZCCHC8
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 8.

NEK2_MOUSE
NC score	0.036261 (rank : 314)	θ value	2.36792 (rank : 169)
Query Neighborhood Hits	279	Target Neighborhood Hits	876	Shared Neighborhood Hits	20
SwissProt Accessions	O35942, O35959	Gene names	Nek2
Domain Architecture
Description	Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (NimA-related protein kinase 2).

NCOR1_HUMAN
NC score	0.035466 (rank : 315)	θ value	6.88961 (rank : 236)
Query Neighborhood Hits	279	Target Neighborhood Hits	577	Shared Neighborhood Hits	78
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

IF2B_HUMAN
NC score	0.034838 (rank : 316)	θ value	5.27518 (rank : 215)
Query Neighborhood Hits	279	Target Neighborhood Hits	60	Shared Neighborhood Hits	17
SwissProt Accessions	P20042, Q9BVU0, Q9UJE4	Gene names	EIF2S2, EIF2B
Domain Architecture
Description	Eukaryotic translation initiation factor 2 subunit 2 (Eukaryotic translation initiation factor 2 subunit beta) (eIF-2-beta).

KI21A_MOUSE
NC score	0.032889 (rank : 317)	θ value	1.38821 (rank : 145)
Query Neighborhood Hits	279	Target Neighborhood Hits	1317	Shared Neighborhood Hits	101
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

OLR1_MOUSE
NC score	0.032487 (rank : 318)	θ value	3.0926 (rank : 186)
Query Neighborhood Hits	279	Target Neighborhood Hits	596	Shared Neighborhood Hits	43
SwissProt Accessions	Q9EQ09	Gene names	Olr1, Lox1
Domain Architecture	No domain graphic available
Description	Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1) (Lectin-type oxidized LDL receptor 1) (Lectin-like oxidized LDL receptor 1) (Lectin-like oxLDL receptor 1) (LOX-1) [Contains: Oxidized low-density lipoprotein receptor 1, soluble form].

CASC3_HUMAN
NC score	0.031461 (rank : 319)	θ value	8.99809 (rank : 257)
Query Neighborhood Hits	279	Target Neighborhood Hits	204	Shared Neighborhood Hits	40
SwissProt Accessions	O15234	Gene names	CASC3, MLN51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein) (Metastatic lymph node protein 51) (Protein MLN 51) (Protein barentsz) (Btz).

LMD1_HUMAN
NC score	0.031408 (rank : 320)	θ value	1.81305 (rank : 154)
Query Neighborhood Hits	279	Target Neighborhood Hits	169	Shared Neighborhood Hits	31
SwissProt Accessions	P29536	Gene names	LMOD1
Domain Architecture
Description	Leiomodin-1 (Leiomodin, muscle form) (64 kDa autoantigen D1) (64 kDa autoantigen 1D) (64 kDa autoantigen 1D3) (Thyroid-associated ophthalmopathy autoantigen) (Smooth muscle leiomodin) (SM-Lmod).

HM20A_MOUSE
NC score	0.031032 (rank : 321)	θ value	5.27518 (rank : 214)
Query Neighborhood Hits	279	Target Neighborhood Hits	348	Shared Neighborhood Hits	55
SwissProt Accessions	Q9DC33, Q3LSF9, Q6NV87, Q8BSK1, Q8C3C1, Q8CAA0, Q9CYG2	Gene names	Hmg20a, Ibraf
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (iBRAF) (Inhibitor of BRAF35) (HMG domain protein HMGX1).

AN32E_MOUSE
NC score	0.030726 (rank : 322)	θ value	8.99809 (rank : 254)
Query Neighborhood Hits	279	Target Neighborhood Hits	257	Shared Neighborhood Hits	18
SwissProt Accessions	P97822, Q3TH89, Q8BPF8, Q8C2L4, Q8C7Q8, Q9CZD2	Gene names	Anp32e, Cpd1
Domain Architecture
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member E (LANP- like protein) (LANP-L) (Cerebellar postnatal development protein 1).

WDR22_HUMAN
NC score	0.030413 (rank : 323)	θ value	0.47712 (rank : 109)
Query Neighborhood Hits	279	Target Neighborhood Hits	328	Shared Neighborhood Hits	17
SwissProt Accessions	Q96JK2, O60559, Q8N3V3, Q8N3V5	Gene names	WDR22, BCRG2, KIAA1824
Domain Architecture
Description	WD repeat protein 22 (Breakpoint cluster region protein 2) (BCRP2).

RPA1_MOUSE
NC score	0.030290 (rank : 324)	θ value	1.06291 (rank : 136)
Query Neighborhood Hits	279	Target Neighborhood Hits	112	Shared Neighborhood Hits	20
SwissProt Accessions	O35134, Q7TSA9	Gene names	Polr1a, Rpa1, Rpo1-4
Domain Architecture
Description	DNA-directed RNA polymerase I largest subunit (EC 2.7.7.6) (RNA polymerase I 194 kDa subunit) (RPA194).

HM20A_HUMAN
NC score	0.030168 (rank : 325)	θ value	5.27518 (rank : 213)
Query Neighborhood Hits	279	Target Neighborhood Hits	343	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NP66, Q53G31, Q9NSF6	Gene names	HMG20A, HMGX1
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (HMG domain-containing protein HMGX1).

WDR22_MOUSE
NC score	0.029190 (rank : 326)	θ value	0.47712 (rank : 110)
Query Neighborhood Hits	279	Target Neighborhood Hits	302	Shared Neighborhood Hits	13
SwissProt Accessions	Q80T85, Q80VT3, Q80ZW6, Q8BIP8, Q8BVK5, Q8K0Q6	Gene names	Wdr22, Kiaa1824
Domain Architecture
Description	WD repeat protein 22.

MDM2_HUMAN
NC score	0.029036 (rank : 327)	θ value	1.38821 (rank : 146)
Query Neighborhood Hits	279	Target Neighborhood Hits	92	Shared Neighborhood Hits	12
SwissProt Accessions	Q00987, Q13226, Q13297, Q13298, Q13299, Q13300, Q13301, Q53XW0, Q71TW9, Q9UGI3, Q9UMT8	Gene names	MDM2
Domain Architecture
Description	Ubiquitin-protein ligase E3 Mdm2 (EC 6.3.2.-) (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein) (Hdm2).

AMOL2_HUMAN
NC score	0.028239 (rank : 328)	θ value	8.99809 (rank : 253)
Query Neighborhood Hits	279	Target Neighborhood Hits	603	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y2J4, Q53EP1, Q96F99, Q9UKB4	Gene names	AMOTL2, KIAA0989
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2 (Leman coiled-coil protein) (LCCP).

UBDC1_MOUSE
NC score	0.028109 (rank : 329)	θ value	0.813845 (rank : 126)
Query Neighborhood Hits	279	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VDI7, Q3TZH3	Gene names	Ubadc1, Kpc2
Domain Architecture	No domain graphic available
Description	Ubiquitin-associated domain-containing protein 1 (E3 ubiquitin-protein ligase subunit KPC2) (Kip1 ubiquitination-promoting complex protein 2).

BCCIP_MOUSE
NC score	0.027702 (rank : 330)	θ value	1.38821 (rank : 141)
Query Neighborhood Hits	279	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CWI3, Q9D1E0	Gene names	Bccip
Domain Architecture	No domain graphic available
Description	BRCA2 and CDKN1A-interacting protein.

K0776_MOUSE
NC score	0.027543 (rank : 331)	θ value	1.06291 (rank : 133)
Query Neighborhood Hits	279	Target Neighborhood Hits	33	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CCJ3, Q3V145, Q6ZQ50, Q8BT70, Q8C484, Q9D8I8	Gene names	Kiaa0776
Domain Architecture	No domain graphic available
Description	Protein KIAA0776.

PPR3A_MOUSE
NC score	0.027160 (rank : 332)	θ value	1.81305 (rank : 159)
Query Neighborhood Hits	279	Target Neighborhood Hits	45	Shared Neighborhood Hits	10
SwissProt Accessions	Q99MR9, Q8BUJ4, Q8BUL0	Gene names	Ppp1r3a, Pp1g
Domain Architecture	No domain graphic available
Description	Protein phosphatase 1 regulatory subunit 3A (Protein phosphatase 1 glycogen-associated regulatory subunit) (Protein phosphatase type-1 glycogen targeting subunit) (RGL).

DDX21_MOUSE
NC score	0.027031 (rank : 333)	θ value	0.0431538 (rank : 63)
Query Neighborhood Hits	279	Target Neighborhood Hits	350	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

RERE_MOUSE
NC score	0.026962 (rank : 334)	θ value	2.36792 (rank : 175)
Query Neighborhood Hits	279	Target Neighborhood Hits	785	Shared Neighborhood Hits	47
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

ABCF1_HUMAN
NC score	0.026134 (rank : 335)	θ value	8.99809 (rank : 252)
Query Neighborhood Hits	279	Target Neighborhood Hits	343	Shared Neighborhood Hits	45
SwissProt Accessions	Q8NE71, O14897, Q69YP6	Gene names	ABCF1, ABC50
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50) (TNF-alpha-stimulated ABC protein).

AKAP2_HUMAN
NC score	0.025645 (rank : 336)	θ value	5.27518 (rank : 207)
Query Neighborhood Hits	279	Target Neighborhood Hits	507	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

TTBK1_HUMAN
NC score	0.025326 (rank : 337)	θ value	0.813845 (rank : 125)
Query Neighborhood Hits	279	Target Neighborhood Hits	1058	Shared Neighborhood Hits	46
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

PTRF_MOUSE
NC score	0.025288 (rank : 338)	θ value	6.88961 (rank : 244)
Query Neighborhood Hits	279	Target Neighborhood Hits	151	Shared Neighborhood Hits	19
SwissProt Accessions	O54724	Gene names	Ptrf
Domain Architecture	No domain graphic available
Description	Polymerase I and transcript release factor.

CA026_HUMAN
NC score	0.025179 (rank : 339)	θ value	3.0926 (rank : 181)
Query Neighborhood Hits	279	Target Neighborhood Hits	87	Shared Neighborhood Hits	16
SwissProt Accessions	Q5T5J6, Q8NEK9, Q9BZQ7, Q9NXQ0	Gene names	C1orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf26.

RERE_HUMAN
NC score	0.025138 (rank : 340)	θ value	8.99809 (rank : 272)
Query Neighborhood Hits	279	Target Neighborhood Hits	779	Shared Neighborhood Hits	46
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

LYAR_MOUSE
NC score	0.024571 (rank : 341)	θ value	8.99809 (rank : 268)
Query Neighborhood Hits	279	Target Neighborhood Hits	153	Shared Neighborhood Hits	25
SwissProt Accessions	Q08288, Q9D9X2	Gene names	Lyar
Domain Architecture	No domain graphic available
Description	Cell growth-regulating nucleolar protein.

SRBS1_HUMAN
NC score	0.024298 (rank : 342)	θ value	1.38821 (rank : 150)
Query Neighborhood Hits	279	Target Neighborhood Hits	396	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

OSTP_HUMAN
NC score	0.023771 (rank : 343)	θ value	6.88961 (rank : 238)
Query Neighborhood Hits	279	Target Neighborhood Hits	36	Shared Neighborhood Hits	11
SwissProt Accessions	P10451, Q15681, Q15682, Q15683, Q8NBK2, Q96IZ1	Gene names	SPP1, OPN
Domain Architecture
Description	Osteopontin precursor (Bone sialoprotein-1) (Secreted phosphoprotein 1) (SPP-1) (Urinary stone protein) (Nephropontin) (Uropontin).

PRG4_HUMAN
NC score	0.023452 (rank : 344)	θ value	6.88961 (rank : 243)
Query Neighborhood Hits	279	Target Neighborhood Hits	764	Shared Neighborhood Hits	36
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

RPA1_HUMAN
NC score	0.023377 (rank : 345)	θ value	6.88961 (rank : 245)
Query Neighborhood Hits	279	Target Neighborhood Hits	106	Shared Neighborhood Hits	15
SwissProt Accessions	O95602, Q9UEH0, Q9UFT9	Gene names	POLR1A
Domain Architecture
Description	DNA-directed RNA polymerase I largest subunit (EC 2.7.7.6) (RNA polymerase I 194 kDa subunit) (RPA194).

WDHD1_MOUSE
NC score	0.022885 (rank : 346)	θ value	2.36792 (rank : 179)
Query Neighborhood Hits	279	Target Neighborhood Hits	414	Shared Neighborhood Hits	29
SwissProt Accessions	P59328, Q6P408	Gene names	Wdhd1, And1
Domain Architecture	No domain graphic available
Description	WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA- binding protein 1) (And-1).

IPP2_MOUSE
NC score	0.022504 (rank : 347)	θ value	4.03905 (rank : 197)
Query Neighborhood Hits	279	Target Neighborhood Hits	49	Shared Neighborhood Hits	8
SwissProt Accessions	Q9DCL8, Q3UD25, Q8C1A6	Gene names	Ppp1r2
Domain Architecture	No domain graphic available
Description	Protein phosphatase inhibitor 2 (IPP-2).

JIP2_HUMAN
NC score	0.022489 (rank : 348)	θ value	2.36792 (rank : 165)
Query Neighborhood Hits	279	Target Neighborhood Hits	288	Shared Neighborhood Hits	18
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

G3BP2_HUMAN
NC score	0.022428 (rank : 349)	θ value	1.38821 (rank : 143)
Query Neighborhood Hits	279	Target Neighborhood Hits	260	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UN86, O60606, O75149, Q9UPA1	Gene names	G3BP2, KIAA0660
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 2 (GAP SH3-domain- binding protein 2) (G3BP-2).

UT14A_MOUSE
NC score	0.022294 (rank : 350)	θ value	6.88961 (rank : 250)
Query Neighborhood Hits	279	Target Neighborhood Hits	177	Shared Neighborhood Hits	27
SwissProt Accessions	Q640M1, Q6A094, Q6EJB4, Q6P6L1, Q9CZK8	Gene names	Utp14a, JsdX, Kiaa0266
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 14 homolog A (Juvenile spermatogonial depletion-like X-linked protein) (Jsd-like X-linked protein).

GP149_HUMAN
NC score	0.022096 (rank : 351)	θ value	1.81305 (rank : 152)
Query Neighborhood Hits	279	Target Neighborhood Hits	68	Shared Neighborhood Hits	4
SwissProt Accessions	Q86SP6	Gene names	GPR149, PGR10
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 149 (G-protein coupled receptor PGR10).

MIER1_MOUSE
NC score	0.022033 (rank : 352)	θ value	4.03905 (rank : 198)
Query Neighborhood Hits	279	Target Neighborhood Hits	84	Shared Neighborhood Hits	14
SwissProt Accessions	Q5UAK0, Q5UAK1, Q5UAK2, Q5UAK3, Q6ZPL6, Q9D402	Gene names	Mier1, Kiaa1610
Domain Architecture	No domain graphic available
Description	Mesoderm induction early response protein 1 (Mi-er1).

DNL1_HUMAN
NC score	0.021693 (rank : 353)	θ value	8.99809 (rank : 265)
Query Neighborhood Hits	279	Target Neighborhood Hits	216	Shared Neighborhood Hits	25
SwissProt Accessions	P18858	Gene names	LIG1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

SRBS1_MOUSE
NC score	0.021284 (rank : 354)	θ value	1.81305 (rank : 162)
Query Neighborhood Hits	279	Target Neighborhood Hits	409	Shared Neighborhood Hits	27
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

MLL3_MOUSE
NC score	0.021147 (rank : 355)	θ value	5.27518 (rank : 219)
Query Neighborhood Hits	279	Target Neighborhood Hits	1399	Shared Neighborhood Hits	77
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

SMCA4_HUMAN
NC score	0.020357 (rank : 356)	θ value	2.36792 (rank : 178)
Query Neighborhood Hits	279	Target Neighborhood Hits	597	Shared Neighborhood Hits	49
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

BRCA1_HUMAN
NC score	0.020243 (rank : 357)	θ value	3.0926 (rank : 180)
Query Neighborhood Hits	279	Target Neighborhood Hits	381	Shared Neighborhood Hits	34
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

AR13B_HUMAN
NC score	0.020212 (rank : 358)	θ value	8.99809 (rank : 255)
Query Neighborhood Hits	279	Target Neighborhood Hits	528	Shared Neighborhood Hits	70
SwissProt Accessions	Q3SXY8, Q504W8	Gene names	ARL13B, ARL2L1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-like protein 13B (ADP-ribosylation factor-like protein 2-like 1) (ARL2-like protein 1).

CHD4_HUMAN
NC score	0.019146 (rank : 359)	θ value	8.99809 (rank : 258)
Query Neighborhood Hits	279	Target Neighborhood Hits	365	Shared Neighborhood Hits	40
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CTDP1_MOUSE
NC score	0.017796 (rank : 360)	θ value	8.99809 (rank : 262)
Query Neighborhood Hits	279	Target Neighborhood Hits	146	Shared Neighborhood Hits	16
SwissProt Accessions	Q7TSG2, Q7TSS7, Q9D4S8	Gene names	Ctdp1, Fcp1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

JHD2C_MOUSE
NC score	0.017768 (rank : 361)	θ value	6.88961 (rank : 232)
Query Neighborhood Hits	279	Target Neighborhood Hits	297	Shared Neighborhood Hits	46
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

RHG25_HUMAN
NC score	0.016787 (rank : 362)	θ value	8.99809 (rank : 273)
Query Neighborhood Hits	279	Target Neighborhood Hits	550	Shared Neighborhood Hits	51
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

MSH6_HUMAN
NC score	0.016352 (rank : 363)	θ value	5.27518 (rank : 220)
Query Neighborhood Hits	279	Target Neighborhood Hits	81	Shared Neighborhood Hits	13
SwissProt Accessions	P52701, O43706, O43917, Q8TCX4, Q9BTB5	Gene names	MSH6, GTBP
Domain Architecture
Description	DNA mismatch repair protein MSH6 (MutS-alpha 160 kDa subunit) (G/T mismatch-binding protein) (GTBP) (GTMBP) (p160).

ADA30_HUMAN
NC score	0.015835 (rank : 364)	θ value	1.06291 (rank : 128)
Query Neighborhood Hits	279	Target Neighborhood Hits	391	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

DDX21_HUMAN
NC score	0.015077 (rank : 365)	θ value	8.99809 (rank : 264)
Query Neighborhood Hits	279	Target Neighborhood Hits	308	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

HS90A_HUMAN
NC score	0.014761 (rank : 366)	θ value	8.99809 (rank : 266)
Query Neighborhood Hits	279	Target Neighborhood Hits	144	Shared Neighborhood Hits	29
SwissProt Accessions	P07900, Q2PP14, Q9BVQ5	Gene names	HSP90AA1, HSP90A, HSPC1, HSPCA
Domain Architecture
Description	Heat shock protein HSP 90-alpha (HSP 86) (NY-REN-38 antigen).

PCDA6_HUMAN
NC score	0.014646 (rank : 367)	θ value	0.47712 (rank : 107)
Query Neighborhood Hits	279	Target Neighborhood Hits	187	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UN73, O75283, Q9NRT8	Gene names	PCDHA6
Domain Architecture
Description	Protocadherin alpha 6 precursor (PCDH-alpha6).

DDX27_HUMAN
NC score	0.014301 (rank : 368)	θ value	1.06291 (rank : 130)
Query Neighborhood Hits	279	Target Neighborhood Hits	197	Shared Neighborhood Hits	28
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

MSH6_MOUSE
NC score	0.013994 (rank : 369)	θ value	6.88961 (rank : 233)
Query Neighborhood Hits	279	Target Neighborhood Hits	55	Shared Neighborhood Hits	8
SwissProt Accessions	P54276, O54710	Gene names	Msh6, Gtmbp
Domain Architecture
Description	DNA mismatch repair protein MSH6 (MutS-alpha 160 kDa subunit) (G/T mismatch-binding protein) (GTBP) (GTMBP) (p160).

PMS1_HUMAN
NC score	0.013800 (rank : 370)	θ value	6.88961 (rank : 241)
Query Neighborhood Hits	279	Target Neighborhood Hits	126	Shared Neighborhood Hits	12
SwissProt Accessions	P54277	Gene names	PMS1, PMSL1
Domain Architecture
Description	PMS1 protein homolog 1 (DNA mismatch repair protein PMS1).

KU70_MOUSE
NC score	0.013510 (rank : 371)	θ value	5.27518 (rank : 216)
Query Neighborhood Hits	279	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	P23475, O88212, Q62027, Q62382, Q62453	Gene names	Xrcc6, G22p1, Ku70
Domain Architecture
Description	ATP-dependent DNA helicase 2 subunit 1 (EC 3.6.1.-) (ATP-dependent DNA helicase II 70 kDa subunit) (Ku autoantigen protein p70 homolog) (Ku70) (CTC box-binding factor 75 kDa subunit) (CTCBF) (CTC75) (DNA- repair protein XRCC6).

PCDA8_HUMAN
NC score	0.013414 (rank : 372)	θ value	2.36792 (rank : 172)
Query Neighborhood Hits	279	Target Neighborhood Hits	187	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y5H6, O75281	Gene names	PCDHA8
Domain Architecture
Description	Protocadherin alpha 8 precursor (PCDH-alpha8).

PCDA9_HUMAN
NC score	0.013206 (rank : 373)	θ value	3.0926 (rank : 187)
Query Neighborhood Hits	279	Target Neighborhood Hits	203	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y5H5, O15053	Gene names	PCDHA9, KIAA0345
Domain Architecture
Description	Protocadherin alpha 9 precursor (PCDH-alpha9).

PCDA3_HUMAN
NC score	0.013196 (rank : 374)	θ value	2.36792 (rank : 171)
Query Neighborhood Hits	279	Target Neighborhood Hits	203	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y5H8, O75286	Gene names	PCDHA3
Domain Architecture
Description	Protocadherin alpha 3 precursor (PCDH-alpha3).

NPHP1_HUMAN
NC score	0.012900 (rank : 375)	θ value	6.88961 (rank : 237)
Query Neighborhood Hits	279	Target Neighborhood Hits	288	Shared Neighborhood Hits	18
SwissProt Accessions	O15259, O14837	Gene names	NPHP1, NPH1
Domain Architecture
Description	Nephrocystin-1 (Juvenile nephronophthisis 1 protein).

PCDA1_HUMAN
NC score	0.012830 (rank : 376)	θ value	4.03905 (rank : 200)
Query Neighborhood Hits	279	Target Neighborhood Hits	199	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y5I3, O75288, Q9NRT7	Gene names	PCDHA1
Domain Architecture
Description	Protocadherin alpha 1 precursor (PCDH-alpha1).

MYC_HUMAN
NC score	0.012821 (rank : 377)	θ value	3.0926 (rank : 184)
Query Neighborhood Hits	279	Target Neighborhood Hits	146	Shared Neighborhood Hits	7
SwissProt Accessions	P01106, P01107, Q14026	Gene names	MYC
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

PCDAB_HUMAN
NC score	0.012791 (rank : 378)	θ value	4.03905 (rank : 201)
Query Neighborhood Hits	279	Target Neighborhood Hits	211	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y5I1, O75279	Gene names	PCDHA11
Domain Architecture
Description	Protocadherin alpha 11 precursor (PCDH-alpha11).

PCDAA_HUMAN
NC score	0.012669 (rank : 379)	θ value	6.88961 (rank : 240)
Query Neighborhood Hits	279	Target Neighborhood Hits	183	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y5I2, O75280, Q9NRU2	Gene names	PCDHA10
Domain Architecture
Description	Protocadherin alpha 10 precursor (PCDH-alpha10).

PCDA7_HUMAN
NC score	0.012589 (rank : 380)	θ value	6.88961 (rank : 239)
Query Neighborhood Hits	279	Target Neighborhood Hits	221	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UN72, O75282	Gene names	PCDHA7
Domain Architecture
Description	Protocadherin alpha 7 precursor (PCDH-alpha7).

PCDA4_HUMAN
NC score	0.012536 (rank : 381)	θ value	8.99809 (rank : 270)
Query Neighborhood Hits	279	Target Neighborhood Hits	193	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UN74, O75285	Gene names	PCDHA4
Domain Architecture
Description	Protocadherin alpha 4 precursor (PCDH-alpha4).

AP4E1_HUMAN
NC score	0.012144 (rank : 382)	θ value	4.03905 (rank : 195)
Query Neighborhood Hits	279	Target Neighborhood Hits	57	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UPM8, Q9Y588	Gene names	AP4E1
Domain Architecture
Description	AP-4 complex subunit epsilon-1 (Adapter-related protein complex 4 epsilon-1 subunit) (Epsilon subunit of AP-4) (AP-4 adapter complex epsilon subunit).

CI082_HUMAN
NC score	0.011357 (rank : 383)	θ value	8.99809 (rank : 259)
Query Neighborhood Hits	279	Target Neighborhood Hits	32	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H8G2, Q5VY32, Q6IPE6, Q96C59	Gene names	C9orf82
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf82.

TNF13_HUMAN
NC score	0.010878 (rank : 384)	θ value	8.99809 (rank : 279)
Query Neighborhood Hits	279	Target Neighborhood Hits	17	Shared Neighborhood Hits	5
SwissProt Accessions	O75888, Q96HV6, Q9P1M8, Q9P1M9	Gene names	TNFSF13, APRIL, TALL2, ZTNF2
Domain Architecture
Description	Tumor necrosis factor ligand superfamily member 13 precursor (A proliferation-inducing ligand) (APRIL) (TNF- and APOL-related leukocyte expressed ligand 2) (TALL-2) (TNF-related death ligand 1) (TRDL-1) (CD256 antigen).

SETB1_MOUSE
NC score	0.010085 (rank : 385)	θ value	6.88961 (rank : 246)
Query Neighborhood Hits	279	Target Neighborhood Hits	150	Shared Neighborhood Hits	13
SwissProt Accessions	O88974, Q922K1	Gene names	Setdb1, Eset
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

ABCA2_HUMAN
NC score	0.009402 (rank : 386)	θ value	1.38821 (rank : 140)
Query Neighborhood Hits	279	Target Neighborhood Hits	143	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BZC7	Gene names	ABCA2, ABC2
Domain Architecture
Description	ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2).

BBX_MOUSE
NC score	0.008903 (rank : 387)	θ value	6.88961 (rank : 229)
Query Neighborhood Hits	279	Target Neighborhood Hits	152	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VBW5, Q3TZK1, Q6NXY8, Q6PEU3, Q8BQJ7, Q8C7E0, Q8CDQ0, Q8CDV1, Q8VI48, Q8VI49, Q8VI50, Q9CS94	Gene names	Bbx, Hbp2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

PZRN4_HUMAN
NC score	0.008049 (rank : 388)	θ value	5.27518 (rank : 223)
Query Neighborhood Hits	279	Target Neighborhood Hits	438	Shared Neighborhood Hits	20
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

ABLM1_HUMAN
NC score	0.006941 (rank : 389)	θ value	0.813845 (rank : 115)
Query Neighborhood Hits	279	Target Neighborhood Hits	387	Shared Neighborhood Hits	7
SwissProt Accessions	O14639, Q15039, Q68CQ9, Q9BUP1	Gene names	ABLIM1, ABLIM, KIAA0059
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 1 (Actin-binding LIM protein family member 1) (abLIM-1) (Actin-binding double-zinc-finger protein) (LIMAB1) (Limatin).

AHI1_HUMAN
NC score	0.006528 (rank : 390)	θ value	5.27518 (rank : 206)
Query Neighborhood Hits	279	Target Neighborhood Hits	537	Shared Neighborhood Hits	20
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

PAX6_HUMAN
NC score	0.005185 (rank : 391)	θ value	1.81305 (rank : 157)
Query Neighborhood Hits	279	Target Neighborhood Hits	383	Shared Neighborhood Hits	4
SwissProt Accessions	P26367, Q6N006, Q99413	Gene names	PAX6, AN2
Domain Architecture
Description	Paired box protein Pax-6 (Oculorhombin) (Aniridia type II protein).

PAX6_MOUSE
NC score	0.005185 (rank : 392)	θ value	1.81305 (rank : 158)
Query Neighborhood Hits	279	Target Neighborhood Hits	383	Shared Neighborhood Hits	4
SwissProt Accessions	P63015, P32117, P70601, Q62222, Q64037, Q8CEI5, Q8VDB5, Q921Q8	Gene names	Pax6, Pax-6, Sey
Domain Architecture	No domain graphic available
Description	Paired box protein Pax-6 (Oculorhombin).

ABCA5_MOUSE
NC score	0.004776 (rank : 393)	θ value	5.27518 (rank : 205)
Query Neighborhood Hits	279	Target Neighborhood Hits	137	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K448, Q3TE17, Q3UUB4, Q6P1Y0, Q6ZPG4, Q810C7, Q8BM46, Q8BXG7	Gene names	Abca5, Kiaa1888
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 5.

PRDM2_HUMAN
NC score	0.003717 (rank : 394)	θ value	6.88961 (rank : 242)
Query Neighborhood Hits	279	Target Neighborhood Hits	1135	Shared Neighborhood Hits	38
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

ZN694_HUMAN
NC score	-0.006565 (rank : 395)	θ value	5.27518 (rank : 226)
Query Neighborhood Hits	279	Target Neighborhood Hits	764	Shared Neighborhood Hits	7
SwissProt Accessions	Q63HK3, Q6ZN77	Gene names	ZNF694
Domain Architecture	No domain graphic available
Description	Zinc finger protein 694.