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Network neighborhood for query Sequence : HUWE1_MOUSE

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HUWE1_MOUSE
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

HUWE1_HUMAN
θ value	0 (rank : 1)	NC score	0.989016 (rank : 2)
Query Neighborhood Hits	406	Target Neighborhood Hits	443	Shared Neighborhood Hits	300
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

HUWE1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	406	Target Neighborhood Hits	406	Shared Neighborhood Hits	406
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

NED4L_HUMAN
θ value	2.81514e-94 (rank : 3)	NC score	0.810475 (rank : 23)
Query Neighborhood Hits	406	Target Neighborhood Hits	238	Shared Neighborhood Hits	43
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

NED4L_MOUSE
θ value	2.81514e-94 (rank : 4)	NC score	0.811742 (rank : 22)
Query Neighborhood Hits	406	Target Neighborhood Hits	231	Shared Neighborhood Hits	42
SwissProt Accessions	Q8CFI0, Q8BRT9, Q8BS42, Q99PK2	Gene names	Nedd4l, Kiaa0439, Nedd4b
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

NEDD4_HUMAN
θ value	4.06505e-93 (rank : 5)	NC score	0.824997 (rank : 21)
Query Neighborhood Hits	406	Target Neighborhood Hits	214	Shared Neighborhood Hits	40
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).

ITCH_MOUSE
θ value	5.30912e-93 (rank : 6)	NC score	0.875344 (rank : 10)
Query Neighborhood Hits	406	Target Neighborhood Hits	127	Shared Neighborhood Hits	37
SwissProt Accessions	Q8C863, O54971	Gene names	Itch
Domain Architecture
Description	Itchy E3 ubiquitin protein ligase (EC 6.3.2.-).

NEDD4_MOUSE
θ value	2.63489e-92 (rank : 7)	NC score	0.830925 (rank : 20)
Query Neighborhood Hits	406	Target Neighborhood Hits	212	Shared Neighborhood Hits	42
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

ITCH_HUMAN
θ value	3.44127e-92 (rank : 8)	NC score	0.868130 (rank : 15)
Query Neighborhood Hits	406	Target Neighborhood Hits	162	Shared Neighborhood Hits	44
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

SMUF1_MOUSE
θ value	4.96919e-91 (rank : 9)	NC score	0.879241 (rank : 4)
Query Neighborhood Hits	406	Target Neighborhood Hits	142	Shared Neighborhood Hits	39
SwissProt Accessions	Q9CUN6, Q3U412, Q8K300	Gene names	Smurf1
Domain Architecture	No domain graphic available
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1).

SMUF2_HUMAN
θ value	4.96919e-91 (rank : 10)	NC score	0.878175 (rank : 8)
Query Neighborhood Hits	406	Target Neighborhood Hits	142	Shared Neighborhood Hits	38
SwissProt Accessions	Q9HAU4, Q9H260	Gene names	SMURF2
Domain Architecture
Description	Smad ubiquitination regulatory factor 2 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF2) (Smad-specific E3 ubiquitin ligase 2) (hSMURF2).

SMUF1_HUMAN
θ value	2.46618e-90 (rank : 11)	NC score	0.882187 (rank : 3)
Query Neighborhood Hits	406	Target Neighborhood Hits	135	Shared Neighborhood Hits	38
SwissProt Accessions	Q9HCE7, O75853, Q9UJT8	Gene names	SMURF1, KIAA1625
Domain Architecture
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) (hSMURF1).

WWP1_HUMAN
θ value	7.93343e-89 (rank : 12)	NC score	0.864459 (rank : 17)
Query Neighborhood Hits	406	Target Neighborhood Hits	262	Shared Neighborhood Hits	72
SwissProt Accessions	Q9H0M0, O00307, Q96BP4	Gene names	WWP1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1) (Atropin-1-interacting protein 5) (AIP5).

WWP1_MOUSE
θ value	7.93343e-89 (rank : 13)	NC score	0.867673 (rank : 16)
Query Neighborhood Hits	406	Target Neighborhood Hits	138	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BZZ3, Q8BIV9, Q8VDP8	Gene names	Wwp1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1).

WWP2_HUMAN
θ value	1.14559e-87 (rank : 14)	NC score	0.868745 (rank : 14)
Query Neighborhood Hits	406	Target Neighborhood Hits	177	Shared Neighborhood Hits	51
SwissProt Accessions	O00308, Q96CZ2, Q9BWN6	Gene names	WWP2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2) (Atrophin-1-interacting protein 2) (AIP2).

WWP2_MOUSE
θ value	1.14559e-87 (rank : 15)	NC score	0.869926 (rank : 12)
Query Neighborhood Hits	406	Target Neighborhood Hits	118	Shared Neighborhood Hits	47
SwissProt Accessions	Q9DBH0, Q8BTG4, Q923F6	Gene names	Wwp2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2).

K0317_MOUSE
θ value	1.84601e-53 (rank : 16)	NC score	0.878197 (rank : 7)
Query Neighborhood Hits	406	Target Neighborhood Hits	43	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CHG5, Q6P9Q1, Q80YC4, Q8C5W5	Gene names	Kiaa0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

K0317_HUMAN
θ value	2.41096e-53 (rank : 17)	NC score	0.878215 (rank : 6)
Query Neighborhood Hits	406	Target Neighborhood Hits	46	Shared Neighborhood Hits	33
SwissProt Accessions	O15033, Q7LDY1, Q8IYY9	Gene names	KIAA0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

UBE3A_HUMAN
θ value	2.66562e-52 (rank : 18)	NC score	0.874774 (rank : 11)
Query Neighborhood Hits	406	Target Neighborhood Hits	49	Shared Neighborhood Hits	34
SwissProt Accessions	Q05086, P78355, Q93066, Q9UEP4, Q9UEP5, Q9UEP6, Q9UEP7, Q9UEP8, Q9UEP9	Gene names	UBE3A, E6AP
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (E6AP ubiquitin-protein ligase) (Oncogenic protein-associated protein E6-AP) (Human papillomavirus E6-associated protein) (NY-REN-54 antigen).

HECD2_HUMAN
θ value	7.75577e-52 (rank : 19)	NC score	0.876076 (rank : 9)
Query Neighborhood Hits	406	Target Neighborhood Hits	41	Shared Neighborhood Hits	33
SwissProt Accessions	Q5U5R9, Q5VZ97, Q5VZ99, Q8TCP5	Gene names	HECTD2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

HECD2_MOUSE
θ value	7.75577e-52 (rank : 20)	NC score	0.878313 (rank : 5)
Query Neighborhood Hits	406	Target Neighborhood Hits	38	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CDU6, Q8CBQ9	Gene names	Hectd2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

UBE3A_MOUSE
θ value	6.14528e-49 (rank : 21)	NC score	0.869827 (rank : 13)
Query Neighborhood Hits	406	Target Neighborhood Hits	47	Shared Neighborhood Hits	35
SwissProt Accessions	O08759, P97482	Gene names	Ube3a
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (Oncogenic protein- associated protein E6-AP).

UBE3C_HUMAN
θ value	1.51363e-47 (rank : 22)	NC score	0.863909 (rank : 18)
Query Neighborhood Hits	406	Target Neighborhood Hits	51	Shared Neighborhood Hits	33
SwissProt Accessions	Q15386, Q8TC15, Q96CR4, Q9UDU3	Gene names	UBE3C, KIAA0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

UBE3C_MOUSE
θ value	9.81109e-47 (rank : 23)	NC score	0.862572 (rank : 19)
Query Neighborhood Hits	406	Target Neighborhood Hits	48	Shared Neighborhood Hits	33
SwissProt Accessions	Q80U95, Q8BQZ6, Q8C7W6, Q8CDJ1, Q8VDL5	Gene names	Ube3c, Kiaa0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

HERC3_HUMAN
θ value	5.21438e-40 (rank : 24)	NC score	0.723631 (rank : 27)
Query Neighborhood Hits	406	Target Neighborhood Hits	62	Shared Neighborhood Hits	35
SwissProt Accessions	Q15034	Gene names	HERC3, KIAA0032
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain protein 3.

HERC2_MOUSE
θ value	1.52067e-31 (rank : 25)	NC score	0.626794 (rank : 31)
Query Neighborhood Hits	406	Target Neighborhood Hits	167	Shared Neighborhood Hits	41
SwissProt Accessions	Q4U2R1, O88473, Q3TRJ8, Q3TS47, Q3TST2, Q3UFQ6, Q3URH7, Q5DU32, Q7TPR5, Q80VV7, Q9QYT1, Q9Z168, Q9Z171	Gene names	Herc2, jdf2, Kiaa0393, rjs
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

HERC2_HUMAN
θ value	5.77852e-31 (rank : 26)	NC score	0.622474 (rank : 32)
Query Neighborhood Hits	406	Target Neighborhood Hits	163	Shared Neighborhood Hits	40
SwissProt Accessions	O95714, Q86SV7, Q86SV8, Q86SV9, Q86YY3, Q86YY4, Q86YY5, Q86YY6, Q86YY7, Q86YY8, Q86YY9, Q86YZ0, Q86YZ1	Gene names	HERC2
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

TRIPC_HUMAN
θ value	4.14116e-29 (rank : 27)	NC score	0.794235 (rank : 24)
Query Neighborhood Hits	406	Target Neighborhood Hits	319	Shared Neighborhood Hits	61
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

HERC5_HUMAN
θ value	3.87602e-27 (rank : 28)	NC score	0.720104 (rank : 28)
Query Neighborhood Hits	406	Target Neighborhood Hits	66	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UII4	Gene names	HERC5, CEB1, CEBP1
Domain Architecture
Description	HECT domain and RCC1-like domain-containing protein 5 (Cyclin-E- binding protein 1).

EDD1_HUMAN
θ value	1.62847e-25 (rank : 29)	NC score	0.698935 (rank : 30)
Query Neighborhood Hits	406	Target Neighborhood Hits	170	Shared Neighborhood Hits	52
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

EDD1_MOUSE
θ value	1.62847e-25 (rank : 30)	NC score	0.700234 (rank : 29)
Query Neighborhood Hits	406	Target Neighborhood Hits	167	Shared Neighborhood Hits	54
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

HECD3_MOUSE
θ value	4.73814e-25 (rank : 31)	NC score	0.729253 (rank : 25)
Query Neighborhood Hits	406	Target Neighborhood Hits	47	Shared Neighborhood Hits	33
SwissProt Accessions	Q3U487, Q3TN76, Q641P3, Q8BQ74, Q8R1L6	Gene names	Hectd3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

HECD3_HUMAN
θ value	1.37858e-24 (rank : 32)	NC score	0.725264 (rank : 26)
Query Neighborhood Hits	406	Target Neighborhood Hits	49	Shared Neighborhood Hits	33
SwissProt Accessions	Q5T447, Q5T448, Q9H783	Gene names	HECTD3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

HECD1_HUMAN
θ value	2.06002e-20 (rank : 33)	NC score	0.556719 (rank : 33)
Query Neighborhood Hits	406	Target Neighborhood Hits	371	Shared Neighborhood Hits	47
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

LEO1_HUMAN
θ value	1.09739e-05 (rank : 34)	NC score	0.103262 (rank : 60)
Query Neighborhood Hits	406	Target Neighborhood Hits	958	Shared Neighborhood Hits	113
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

TXND2_HUMAN
θ value	1.09739e-05 (rank : 35)	NC score	0.098663 (rank : 66)
Query Neighborhood Hits	406	Target Neighborhood Hits	793	Shared Neighborhood Hits	100
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

LEO1_MOUSE
θ value	1.43324e-05 (rank : 36)	NC score	0.100589 (rank : 63)
Query Neighborhood Hits	406	Target Neighborhood Hits	946	Shared Neighborhood Hits	109
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

MAGE1_HUMAN
θ value	9.29e-05 (rank : 37)	NC score	0.063887 (rank : 135)
Query Neighborhood Hits	406	Target Neighborhood Hits	1389	Shared Neighborhood Hits	118
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

NFH_MOUSE
θ value	0.000158464 (rank : 38)	NC score	0.058126 (rank : 157)
Query Neighborhood Hits	406	Target Neighborhood Hits	2247	Shared Neighborhood Hits	182
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

ADDA_MOUSE
θ value	0.00035302 (rank : 39)	NC score	0.063424 (rank : 137)
Query Neighborhood Hits	406	Target Neighborhood Hits	198	Shared Neighborhood Hits	41
SwissProt Accessions	Q9QYC0, Q9JLE3	Gene names	Add1
Domain Architecture
Description	Alpha-adducin (Erythrocyte adducin subunit alpha).

AKA12_HUMAN
θ value	0.000602161 (rank : 40)	NC score	0.109257 (rank : 59)
Query Neighborhood Hits	406	Target Neighborhood Hits	825	Shared Neighborhood Hits	111
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

MYO9B_HUMAN
θ value	0.000786445 (rank : 41)	NC score	0.024650 (rank : 302)
Query Neighborhood Hits	406	Target Neighborhood Hits	641	Shared Neighborhood Hits	66
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

NACAM_MOUSE
θ value	0.00175202 (rank : 42)	NC score	0.085126 (rank : 83)
Query Neighborhood Hits	406	Target Neighborhood Hits	1866	Shared Neighborhood Hits	164
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

TP53B_HUMAN
θ value	0.00175202 (rank : 43)	NC score	0.083684 (rank : 87)
Query Neighborhood Hits	406	Target Neighborhood Hits	413	Shared Neighborhood Hits	73
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TCAL5_HUMAN
θ value	0.00228821 (rank : 44)	NC score	0.065889 (rank : 127)
Query Neighborhood Hits	406	Target Neighborhood Hits	806	Shared Neighborhood Hits	90
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

TXND2_MOUSE
θ value	0.00509761 (rank : 45)	NC score	0.083199 (rank : 90)
Query Neighborhood Hits	406	Target Neighborhood Hits	828	Shared Neighborhood Hits	92
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

BSCL2_HUMAN
θ value	0.00665767 (rank : 46)	NC score	0.103027 (rank : 61)
Query Neighborhood Hits	406	Target Neighborhood Hits	148	Shared Neighborhood Hits	30
SwissProt Accessions	Q96G97, Q96SV1, Q9BSQ0	Gene names	BSCL2
Domain Architecture	No domain graphic available
Description	Seipin (Bernardinelli-Seip congenital lipodystrophy type 2 protein).

IWS1_MOUSE
θ value	0.00665767 (rank : 47)	NC score	0.084104 (rank : 86)
Query Neighborhood Hits	406	Target Neighborhood Hits	1258	Shared Neighborhood Hits	144
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

ZFY1_MOUSE
θ value	0.00665767 (rank : 48)	NC score	0.005783 (rank : 456)
Query Neighborhood Hits	406	Target Neighborhood Hits	790	Shared Neighborhood Hits	31
SwissProt Accessions	P10925	Gene names	Zfy1, Zfy-1
Domain Architecture
Description	Zinc finger Y-chromosomal protein 1.

PRG4_HUMAN
θ value	0.00869519 (rank : 49)	NC score	0.082031 (rank : 92)
Query Neighborhood Hits	406	Target Neighborhood Hits	764	Shared Neighborhood Hits	112
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

RTN4_HUMAN
θ value	0.00869519 (rank : 50)	NC score	0.065991 (rank : 126)
Query Neighborhood Hits	406	Target Neighborhood Hits	357	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

NSBP1_MOUSE
θ value	0.0113563 (rank : 51)	NC score	0.095186 (rank : 69)
Query Neighborhood Hits	406	Target Neighborhood Hits	681	Shared Neighborhood Hits	91
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

ZSCA5_HUMAN
θ value	0.0113563 (rank : 52)	NC score	0.003028 (rank : 474)
Query Neighborhood Hits	406	Target Neighborhood Hits	862	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BUG6	Gene names	ZSCAN5, ZNF495
Domain Architecture	No domain graphic available
Description	Zinc finger and SCAN domain-containing protein 5 (Zinc finger protein 495).

BRD8_MOUSE
θ value	0.0148317 (rank : 53)	NC score	0.073048 (rank : 106)
Query Neighborhood Hits	406	Target Neighborhood Hits	422	Shared Neighborhood Hits	58
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

MATR3_MOUSE
θ value	0.0148317 (rank : 54)	NC score	0.077674 (rank : 99)
Query Neighborhood Hits	406	Target Neighborhood Hits	321	Shared Neighborhood Hits	43
SwissProt Accessions	Q8K310	Gene names	Matr3
Domain Architecture	No domain graphic available
Description	Matrin-3.

SON_HUMAN
θ value	0.0148317 (rank : 55)	NC score	0.050295 (rank : 201)
Query Neighborhood Hits	406	Target Neighborhood Hits	1568	Shared Neighborhood Hits	123
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

ATX2_MOUSE
θ value	0.0193708 (rank : 56)	NC score	0.066734 (rank : 123)
Query Neighborhood Hits	406	Target Neighborhood Hits	445	Shared Neighborhood Hits	64
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

FBX34_MOUSE
θ value	0.0193708 (rank : 57)	NC score	0.050846 (rank : 200)
Query Neighborhood Hits	406	Target Neighborhood Hits	100	Shared Neighborhood Hits	11
SwissProt Accessions	Q80XI1, Q9D290	Gene names	Fbxo34
Domain Architecture	No domain graphic available
Description	F-box only protein 34.

REV1_MOUSE
θ value	0.0193708 (rank : 58)	NC score	0.065331 (rank : 132)
Query Neighborhood Hits	406	Target Neighborhood Hits	67	Shared Neighborhood Hits	17
SwissProt Accessions	Q920Q2, Q9QXV2	Gene names	Rev1l, Rev1
Domain Architecture	No domain graphic available
Description	DNA repair protein REV1 (EC 2.7.7.-) (Rev1-like terminal deoxycytidyl transferase).

ATX2_HUMAN
θ value	0.0252991 (rank : 59)	NC score	0.061558 (rank : 144)
Query Neighborhood Hits	406	Target Neighborhood Hits	375	Shared Neighborhood Hits	46
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

CC47_MOUSE
θ value	0.0252991 (rank : 60)	NC score	0.065792 (rank : 129)
Query Neighborhood Hits	406	Target Neighborhood Hits	245	Shared Neighborhood Hits	31
SwissProt Accessions	Q9D024, Q3TSB5, Q3V1S7, Q8C5D9, Q920S6	Gene names	Ccdc47, Asp4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor (Adipocyte-specific protein 4).

ERIC1_HUMAN
θ value	0.0252991 (rank : 61)	NC score	0.085464 (rank : 82)
Query Neighborhood Hits	406	Target Neighborhood Hits	364	Shared Neighborhood Hits	55
SwissProt Accessions	Q86X53, Q9P063	Gene names	ERICH1
Domain Architecture	No domain graphic available
Description	Glutamate-rich protein 1.

ETV3_MOUSE
θ value	0.0252991 (rank : 62)	NC score	0.036843 (rank : 240)
Query Neighborhood Hits	406	Target Neighborhood Hits	128	Shared Neighborhood Hits	14
SwissProt Accessions	Q8R4Z4, Q9QZW1	Gene names	Etv3, Mets, Pe1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

RPGR_HUMAN
θ value	0.0252991 (rank : 63)	NC score	0.119478 (rank : 58)
Query Neighborhood Hits	406	Target Neighborhood Hits	279	Shared Neighborhood Hits	38
SwissProt Accessions	Q92834, O00702, O00737, Q8N5T6, Q93039, Q9HD29, Q9UMR1	Gene names	RPGR, RP3, XLRP3
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator.

BRD8_HUMAN
θ value	0.0330416 (rank : 64)	NC score	0.059085 (rank : 151)
Query Neighborhood Hits	406	Target Neighborhood Hits	292	Shared Neighborhood Hits	37
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

PEG3_MOUSE
θ value	0.0330416 (rank : 65)	NC score	0.015695 (rank : 373)
Query Neighborhood Hits	406	Target Neighborhood Hits	1101	Shared Neighborhood Hits	76
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

TF2AY_MOUSE
θ value	0.0330416 (rank : 66)	NC score	0.067421 (rank : 119)
Query Neighborhood Hits	406	Target Neighborhood Hits	51	Shared Neighborhood Hits	12
SwissProt Accessions	Q8R4I4, Q99PM2, Q9DAF4	Gene names	Gtf2a1lf, Alf
Domain Architecture
Description	TFIIA-alpha and beta-like factor (General transcription factor II A, 1-like factor).

TGON2_HUMAN
θ value	0.0330416 (rank : 67)	NC score	0.085714 (rank : 81)
Query Neighborhood Hits	406	Target Neighborhood Hits	1037	Shared Neighborhood Hits	123
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

AMPH_HUMAN
θ value	0.0431538 (rank : 68)	NC score	0.048848 (rank : 202)
Query Neighborhood Hits	406	Target Neighborhood Hits	455	Shared Neighborhood Hits	59
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

NSD1_MOUSE
θ value	0.0431538 (rank : 69)	NC score	0.036864 (rank : 239)
Query Neighborhood Hits	406	Target Neighborhood Hits	472	Shared Neighborhood Hits	49
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

SEC63_HUMAN
θ value	0.0431538 (rank : 70)	NC score	0.051085 (rank : 197)
Query Neighborhood Hits	406	Target Neighborhood Hits	586	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

DMXL2_HUMAN
θ value	0.0563607 (rank : 71)	NC score	0.028362 (rank : 279)
Query Neighborhood Hits	406	Target Neighborhood Hits	374	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TDJ6, O94938	Gene names	DMXL2, KIAA0856
Domain Architecture	No domain graphic available
Description	Protein DmX-like 2 (Rabconnectin-3).

BRCA1_MOUSE
θ value	0.0736092 (rank : 72)	NC score	0.034475 (rank : 252)
Query Neighborhood Hits	406	Target Neighborhood Hits	436	Shared Neighborhood Hits	27
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

NIN_MOUSE
θ value	0.0736092 (rank : 73)	NC score	0.019672 (rank : 330)
Query Neighborhood Hits	406	Target Neighborhood Hits	1376	Shared Neighborhood Hits	63
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

OSBL8_HUMAN
θ value	0.0736092 (rank : 74)	NC score	0.037962 (rank : 232)
Query Neighborhood Hits	406	Target Neighborhood Hits	289	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

ADDB_MOUSE
θ value	0.0961366 (rank : 75)	NC score	0.048229 (rank : 207)
Query Neighborhood Hits	406	Target Neighborhood Hits	574	Shared Neighborhood Hits	75
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

ASPH_HUMAN
θ value	0.0961366 (rank : 76)	NC score	0.071380 (rank : 109)
Query Neighborhood Hits	406	Target Neighborhood Hits	158	Shared Neighborhood Hits	23
SwissProt Accessions	Q12797	Gene names	ASPH
Domain Architecture
Description	Aspartyl/asparaginyl beta-hydroxylase (EC 1.14.11.16) (Aspartate beta- hydroxylase) (ASP beta-hydroxylase) (Peptide-aspartate beta- dioxygenase).

DSPP_HUMAN
θ value	0.0961366 (rank : 77)	NC score	0.084517 (rank : 85)
Query Neighborhood Hits	406	Target Neighborhood Hits	645	Shared Neighborhood Hits	100
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

NU214_HUMAN
θ value	0.0961366 (rank : 78)	NC score	0.079894 (rank : 95)
Query Neighborhood Hits	406	Target Neighborhood Hits	657	Shared Neighborhood Hits	85
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

ZKSC1_HUMAN
θ value	0.0961366 (rank : 79)	NC score	0.002664 (rank : 481)
Query Neighborhood Hits	406	Target Neighborhood Hits	949	Shared Neighborhood Hits	49
SwissProt Accessions	P17029, P52745, Q8TBW5, Q8TEK7	Gene names	ZKSCAN1, KOX18, ZNF139, ZNF36
Domain Architecture	No domain graphic available
Description	Zinc finger with KRAB and SCAN domain-containing protein 1 (Zinc finger protein 36) (Zinc finger protein KOX18).

ARHG3_MOUSE
θ value	0.125558 (rank : 80)	NC score	0.025639 (rank : 293)
Query Neighborhood Hits	406	Target Neighborhood Hits	85	Shared Neighborhood Hits	6
SwissProt Accessions	Q91X46, Q8CDM0, Q91VY4, Q99K14, Q9DC31	Gene names	Arhgef3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3.

CQ028_MOUSE
θ value	0.125558 (rank : 81)	NC score	0.052091 (rank : 190)
Query Neighborhood Hits	406	Target Neighborhood Hits	54	Shared Neighborhood Hits	12
SwissProt Accessions	Q8R1F6, Q8C8V6	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C17orf28 homolog.

K1802_MOUSE
θ value	0.125558 (rank : 82)	NC score	0.031530 (rank : 266)
Query Neighborhood Hits	406	Target Neighborhood Hits	1596	Shared Neighborhood Hits	104
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

NCOR2_HUMAN
θ value	0.125558 (rank : 83)	NC score	0.067137 (rank : 122)
Query Neighborhood Hits	406	Target Neighborhood Hits	870	Shared Neighborhood Hits	104
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

PTN13_MOUSE
θ value	0.125558 (rank : 84)	NC score	0.012504 (rank : 400)
Query Neighborhood Hits	406	Target Neighborhood Hits	426	Shared Neighborhood Hits	29
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

CK024_MOUSE
θ value	0.163984 (rank : 85)	NC score	0.068420 (rank : 115)
Query Neighborhood Hits	406	Target Neighborhood Hits	307	Shared Neighborhood Hits	55
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

CUTL1_MOUSE
θ value	0.163984 (rank : 86)	NC score	0.019931 (rank : 328)
Query Neighborhood Hits	406	Target Neighborhood Hits	1620	Shared Neighborhood Hits	102
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

E2F4_HUMAN
θ value	0.163984 (rank : 87)	NC score	0.036816 (rank : 241)
Query Neighborhood Hits	406	Target Neighborhood Hits	188	Shared Neighborhood Hits	21
SwissProt Accessions	Q16254, Q12991, Q15328	Gene names	E2F4
Domain Architecture
Description	Transcription factor E2F4 (E2F-4).

LEUK_HUMAN
θ value	0.163984 (rank : 88)	NC score	0.052219 (rank : 189)
Query Neighborhood Hits	406	Target Neighborhood Hits	213	Shared Neighborhood Hits	42
SwissProt Accessions	P16150	Gene names	SPN, CD43
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Galactoglycoprotein) (GALGP) (CD43 antigen).

MATR3_HUMAN
θ value	0.163984 (rank : 89)	NC score	0.063696 (rank : 136)
Query Neighborhood Hits	406	Target Neighborhood Hits	325	Shared Neighborhood Hits	51
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

MUC1_HUMAN
θ value	0.163984 (rank : 90)	NC score	0.037085 (rank : 237)
Query Neighborhood Hits	406	Target Neighborhood Hits	975	Shared Neighborhood Hits	76
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

PERP_MOUSE
θ value	0.163984 (rank : 91)	NC score	0.057804 (rank : 159)
Query Neighborhood Hits	406	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JK95, Q9JI77	Gene names	Perp, Krtcap1
Domain Architecture	No domain graphic available
Description	p53 apoptosis effector related to PMP-22 (Keratinocytes-associated protein 1) (KCP-1).

SEC63_MOUSE
θ value	0.163984 (rank : 92)	NC score	0.046807 (rank : 212)
Query Neighborhood Hits	406	Target Neighborhood Hits	601	Shared Neighborhood Hits	60
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

ALMS1_HUMAN
θ value	0.21417 (rank : 93)	NC score	0.033611 (rank : 258)
Query Neighborhood Hits	406	Target Neighborhood Hits	356	Shared Neighborhood Hits	55
SwissProt Accessions	Q8TCU4, Q53S05, Q580Q8, Q86VP9, Q9Y4G4	Gene names	ALMS1, KIAA0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1.

BSN_HUMAN
θ value	0.21417 (rank : 94)	NC score	0.046972 (rank : 211)
Query Neighborhood Hits	406	Target Neighborhood Hits	1537	Shared Neighborhood Hits	123
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

E41L3_MOUSE
θ value	0.21417 (rank : 95)	NC score	0.020748 (rank : 323)
Query Neighborhood Hits	406	Target Neighborhood Hits	250	Shared Neighborhood Hits	35
SwissProt Accessions	Q9WV92, Q9R102	Gene names	Epb41l3, Dal1, Epb4.1l3
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1).

GP73_MOUSE
θ value	0.21417 (rank : 96)	NC score	0.037757 (rank : 234)
Query Neighborhood Hits	406	Target Neighborhood Hits	506	Shared Neighborhood Hits	42
SwissProt Accessions	Q91XA2	Gene names	Golph2
Domain Architecture	No domain graphic available
Description	Golgi phosphoprotein 2 (Golgi membrane protein GP73).

MAGC1_HUMAN
θ value	0.21417 (rank : 97)	NC score	0.030669 (rank : 270)
Query Neighborhood Hits	406	Target Neighborhood Hits	431	Shared Neighborhood Hits	65
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

MYPT1_HUMAN
θ value	0.21417 (rank : 98)	NC score	0.015723 (rank : 372)
Query Neighborhood Hits	406	Target Neighborhood Hits	723	Shared Neighborhood Hits	50
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

REV1_HUMAN
θ value	0.21417 (rank : 99)	NC score	0.052292 (rank : 188)
Query Neighborhood Hits	406	Target Neighborhood Hits	56	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UBZ9, O95941, Q9C0J4, Q9NUP2	Gene names	REV1L, REV1
Domain Architecture	No domain graphic available
Description	DNA repair protein REV1 (EC 2.7.7.-) (Rev1-like terminal deoxycytidyl transferase) (Alpha integrin-binding protein 80) (AIBP80).

TITIN_HUMAN
θ value	0.21417 (rank : 100)	NC score	0.013992 (rank : 385)
Query Neighborhood Hits	406	Target Neighborhood Hits	2923	Shared Neighborhood Hits	150
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

ZN750_MOUSE
θ value	0.21417 (rank : 101)	NC score	0.056563 (rank : 165)
Query Neighborhood Hits	406	Target Neighborhood Hits	346	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

BPAEA_HUMAN
θ value	0.279714 (rank : 102)	NC score	0.024072 (rank : 307)
Query Neighborhood Hits	406	Target Neighborhood Hits	1369	Shared Neighborhood Hits	61
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CASC3_MOUSE
θ value	0.279714 (rank : 103)	NC score	0.043973 (rank : 218)
Query Neighborhood Hits	406	Target Neighborhood Hits	333	Shared Neighborhood Hits	51
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

CN155_HUMAN
θ value	0.279714 (rank : 104)	NC score	0.095348 (rank : 68)
Query Neighborhood Hits	406	Target Neighborhood Hits	385	Shared Neighborhood Hits	69
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

IWS1_HUMAN
θ value	0.279714 (rank : 105)	NC score	0.079987 (rank : 94)
Query Neighborhood Hits	406	Target Neighborhood Hits	1241	Shared Neighborhood Hits	141
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

K0460_HUMAN
θ value	0.279714 (rank : 106)	NC score	0.048257 (rank : 206)
Query Neighborhood Hits	406	Target Neighborhood Hits	357	Shared Neighborhood Hits	51
SwissProt Accessions	Q5VT52, O75048, Q5VT53, Q6MZL4, Q86XD2	Gene names	KIAA0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

RAG2_MOUSE
θ value	0.279714 (rank : 107)	NC score	0.047405 (rank : 210)
Query Neighborhood Hits	406	Target Neighborhood Hits	40	Shared Neighborhood Hits	8
SwissProt Accessions	P21784	Gene names	Rag2, Rag-2
Domain Architecture
Description	V(D)J recombination-activating protein 2 (RAG-2).

SGP50_MOUSE
θ value	0.279714 (rank : 108)	NC score	0.089386 (rank : 76)
Query Neighborhood Hits	406	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q02596	Gene names	Glycam1
Domain Architecture
Description	Sulfated 50 kDa glycoprotein precursor (SGP50) (Endothelial ligand FOR L-selectin) (Glycosylation-dependent cell adhesion molecule 1) (GlyCAM-1) (MC26).

VPS72_HUMAN
θ value	0.279714 (rank : 109)	NC score	0.062924 (rank : 139)
Query Neighborhood Hits	406	Target Neighborhood Hits	274	Shared Neighborhood Hits	32
SwissProt Accessions	Q15906, Q53GJ2, Q5U0R4	Gene names	VPS72, TCFL1, YL1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

VPS72_MOUSE
θ value	0.279714 (rank : 110)	NC score	0.065367 (rank : 131)
Query Neighborhood Hits	406	Target Neighborhood Hits	286	Shared Neighborhood Hits	34
SwissProt Accessions	Q62481, Q3U2N4, Q810A9, Q99K81	Gene names	Vps72, Tcfl1, Yl1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

ZCC2_HUMAN
θ value	0.279714 (rank : 111)	NC score	0.034096 (rank : 254)
Query Neighborhood Hits	406	Target Neighborhood Hits	47	Shared Neighborhood Hits	5
SwissProt Accessions	Q7Z2W4, Q8IW57, Q8TAJ3, Q96N79, Q9H8R9, Q9P0Y7	Gene names	ZC3HAV1, ZC3HDC2
Domain Architecture
Description	Zinc finger CCCH type antiviral protein 1 (Zinc finger CCCH domain- containing protein 2).

FGD6_HUMAN
θ value	0.365318 (rank : 112)	NC score	0.013104 (rank : 393)
Query Neighborhood Hits	406	Target Neighborhood Hits	237	Shared Neighborhood Hits	18
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

LCP2_HUMAN
θ value	0.365318 (rank : 113)	NC score	0.030584 (rank : 271)
Query Neighborhood Hits	406	Target Neighborhood Hits	531	Shared Neighborhood Hits	53
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

NALP5_MOUSE
θ value	0.365318 (rank : 114)	NC score	0.029126 (rank : 277)
Query Neighborhood Hits	406	Target Neighborhood Hits	560	Shared Neighborhood Hits	58
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

NEK1_MOUSE
θ value	0.365318 (rank : 115)	NC score	0.003849 (rank : 470)
Query Neighborhood Hits	406	Target Neighborhood Hits	1311	Shared Neighborhood Hits	75
SwissProt Accessions	P51954	Gene names	Nek1
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1).

OGFR_MOUSE
θ value	0.365318 (rank : 116)	NC score	0.052087 (rank : 191)
Query Neighborhood Hits	406	Target Neighborhood Hits	584	Shared Neighborhood Hits	69
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

RAI1_HUMAN
θ value	0.365318 (rank : 117)	NC score	0.031635 (rank : 265)
Query Neighborhood Hits	406	Target Neighborhood Hits	360	Shared Neighborhood Hits	41
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

RERE_HUMAN
θ value	0.365318 (rank : 118)	NC score	0.044070 (rank : 217)
Query Neighborhood Hits	406	Target Neighborhood Hits	779	Shared Neighborhood Hits	98
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

RGS3_MOUSE
θ value	0.365318 (rank : 119)	NC score	0.045124 (rank : 215)
Query Neighborhood Hits	406	Target Neighborhood Hits	1621	Shared Neighborhood Hits	130
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

AKAP2_MOUSE
θ value	0.47712 (rank : 120)	NC score	0.039609 (rank : 230)
Query Neighborhood Hits	406	Target Neighborhood Hits	385	Shared Neighborhood Hits	55
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

BSCL2_MOUSE
θ value	0.47712 (rank : 121)	NC score	0.064136 (rank : 134)
Query Neighborhood Hits	406	Target Neighborhood Hits	94	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Z2E9, Q810B0, Q9JJC2, Q9JMF1	Gene names	Bscl2, Gng3lg
Domain Architecture	No domain graphic available
Description	Seipin (Bernardinelli-Seip congenital lipodystrophy type 2 protein homolog).

INCE_HUMAN
θ value	0.47712 (rank : 122)	NC score	0.029395 (rank : 275)
Query Neighborhood Hits	406	Target Neighborhood Hits	978	Shared Neighborhood Hits	84
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

LRBA_HUMAN
θ value	0.47712 (rank : 123)	NC score	0.019015 (rank : 336)
Query Neighborhood Hits	406	Target Neighborhood Hits	196	Shared Neighborhood Hits	19
SwissProt Accessions	P50851, Q9H2U3, Q9H2U4	Gene names	LRBA, BGL, CDC4L, LBA
Domain Architecture
Description	Lipopolysaccharide-responsive and beige-like anchor protein (CDC4-like protein) (Beige-like protein).

MUC7_HUMAN
θ value	0.47712 (rank : 124)	NC score	0.083460 (rank : 88)
Query Neighborhood Hits	406	Target Neighborhood Hits	538	Shared Neighborhood Hits	91
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

PODXL_HUMAN
θ value	0.47712 (rank : 125)	NC score	0.062168 (rank : 142)
Query Neighborhood Hits	406	Target Neighborhood Hits	191	Shared Neighborhood Hits	44
SwissProt Accessions	O00592	Gene names	PODXL, PCLP, PCLP1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

TP53B_MOUSE
θ value	0.47712 (rank : 126)	NC score	0.076218 (rank : 100)
Query Neighborhood Hits	406	Target Neighborhood Hits	644	Shared Neighborhood Hits	100
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

BPA1_MOUSE
θ value	0.62314 (rank : 127)	NC score	0.019279 (rank : 333)
Query Neighborhood Hits	406	Target Neighborhood Hits	1477	Shared Neighborhood Hits	76
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

BPAEA_MOUSE
θ value	0.62314 (rank : 128)	NC score	0.018359 (rank : 344)
Query Neighborhood Hits	406	Target Neighborhood Hits	1480	Shared Neighborhood Hits	66
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CAMKV_HUMAN
θ value	0.62314 (rank : 129)	NC score	0.005438 (rank : 462)
Query Neighborhood Hits	406	Target Neighborhood Hits	1084	Shared Neighborhood Hits	61
SwissProt Accessions	Q8NCB2, Q6FIB8, Q8NBS8, Q8NC85, Q8NDU4, Q8WTT8, Q9BQC9, Q9H0Q5	Gene names	CAMKV
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

CQ028_HUMAN
θ value	0.62314 (rank : 130)	NC score	0.041663 (rank : 224)
Query Neighborhood Hits	406	Target Neighborhood Hits	56	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IV36, Q8N5L6, Q8TE83, Q9NT34	Gene names	C17orf28, DMC1
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C17orf28 (Down-regulated in multiple cancers- 1).

CS016_HUMAN
θ value	0.62314 (rank : 131)	NC score	0.056560 (rank : 166)
Query Neighborhood Hits	406	Target Neighborhood Hits	310	Shared Neighborhood Hits	54
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

F10A5_HUMAN
θ value	0.62314 (rank : 132)	NC score	0.035435 (rank : 248)
Query Neighborhood Hits	406	Target Neighborhood Hits	277	Shared Neighborhood Hits	24
SwissProt Accessions	Q8NFI4	Gene names	FAM10A5
Domain Architecture	No domain graphic available
Description	Protein FAM10A5.

K0460_MOUSE
θ value	0.62314 (rank : 133)	NC score	0.048478 (rank : 204)
Query Neighborhood Hits	406	Target Neighborhood Hits	374	Shared Neighborhood Hits	58
SwissProt Accessions	Q6NXI6, Q3U3L8, Q6ZQA7	Gene names	Kiaa0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

NASP_HUMAN
θ value	0.62314 (rank : 134)	NC score	0.068230 (rank : 116)
Query Neighborhood Hits	406	Target Neighborhood Hits	709	Shared Neighborhood Hits	97
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

POLI_MOUSE
θ value	0.62314 (rank : 135)	NC score	0.040969 (rank : 226)
Query Neighborhood Hits	406	Target Neighborhood Hits	27	Shared Neighborhood Hits	7
SwissProt Accessions	Q6R3M4, Q641P1, Q6R3M3, Q9R1A6	Gene names	Poli, Rad30b
Domain Architecture	No domain graphic available
Description	DNA polymerase iota (EC 2.7.7.7) (Rad30 homolog B).

TARA_HUMAN
θ value	0.62314 (rank : 136)	NC score	0.056705 (rank : 163)
Query Neighborhood Hits	406	Target Neighborhood Hits	1626	Shared Neighborhood Hits	137
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TULP4_HUMAN
θ value	0.62314 (rank : 137)	NC score	0.025020 (rank : 301)
Query Neighborhood Hits	406	Target Neighborhood Hits	426	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

APBB1_HUMAN
θ value	0.813845 (rank : 138)	NC score	0.051166 (rank : 196)
Query Neighborhood Hits	406	Target Neighborhood Hits	62	Shared Neighborhood Hits	15
SwissProt Accessions	O00213, Q96A93	Gene names	APBB1, FE65
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein).

DMP1_HUMAN
θ value	0.813845 (rank : 139)	NC score	0.087131 (rank : 79)
Query Neighborhood Hits	406	Target Neighborhood Hits	491	Shared Neighborhood Hits	90
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

DNMBP_HUMAN
θ value	0.813845 (rank : 140)	NC score	0.017601 (rank : 354)
Query Neighborhood Hits	406	Target Neighborhood Hits	413	Shared Neighborhood Hits	27
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

DTX2_HUMAN
θ value	0.813845 (rank : 141)	NC score	0.028474 (rank : 278)
Query Neighborhood Hits	406	Target Neighborhood Hits	84	Shared Neighborhood Hits	14
SwissProt Accessions	Q86UW9, Q96H69, Q9H890, Q9P200	Gene names	DTX2, KIAA1528
Domain Architecture
Description	Protein deltex-2 (Deltex-2) (Deltex2) (hDTX2).

F10A1_HUMAN
θ value	0.813845 (rank : 142)	NC score	0.035069 (rank : 249)
Query Neighborhood Hits	406	Target Neighborhood Hits	312	Shared Neighborhood Hits	32
SwissProt Accessions	P50502, O14999	Gene names	ST13, FAM10A1, HIP, SNC6
Domain Architecture
Description	Hsc70-interacting protein (Hip) (Suppression of tumorigenicity protein 13) (Putative tumor suppressor ST13) (Protein FAM10A1) (Progesterone receptor-associated p48 protein) (NY-REN-33 antigen).

KAISO_HUMAN
θ value	0.813845 (rank : 143)	NC score	0.002542 (rank : 482)
Query Neighborhood Hits	406	Target Neighborhood Hits	840	Shared Neighborhood Hits	35
SwissProt Accessions	Q86T24, O00319, Q7Z361, Q8IVP6, Q8N3P0	Gene names	ZBTB33, KAISO, ZNF348
Domain Architecture	No domain graphic available
Description	Transcriptional regulator Kaiso (Zinc finger and BTB domain-containing protein 33).

NF2L3_HUMAN
θ value	0.813845 (rank : 144)	NC score	0.025591 (rank : 294)
Query Neighborhood Hits	406	Target Neighborhood Hits	150	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y4A8, Q6NUS0, Q7Z498, Q86UJ4, Q86VR5, Q9UQA4	Gene names	NFE2L3, NRF3
Domain Architecture	No domain graphic available
Description	Nuclear factor erythroid 2-related factor 3 (NF-E2-related factor 3) (NFE2-related factor 3) (Nuclear factor, erythroid derived 2, like 3).

PF21A_HUMAN
θ value	0.813845 (rank : 145)	NC score	0.019631 (rank : 331)
Query Neighborhood Hits	406	Target Neighborhood Hits	303	Shared Neighborhood Hits	28
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

POLI_HUMAN
θ value	0.813845 (rank : 146)	NC score	0.040799 (rank : 227)
Query Neighborhood Hits	406	Target Neighborhood Hits	28	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UNA4, Q8N590, Q9H0S1, Q9NYH6	Gene names	POLI, RAD30B
Domain Architecture	No domain graphic available
Description	DNA polymerase iota (EC 2.7.7.7) (RAD30 homolog B) (Eta2).

PTPRJ_MOUSE
θ value	0.813845 (rank : 147)	NC score	0.010636 (rank : 416)
Query Neighborhood Hits	406	Target Neighborhood Hits	188	Shared Neighborhood Hits	10
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

SELPL_MOUSE
θ value	0.813845 (rank : 148)	NC score	0.054756 (rank : 177)
Query Neighborhood Hits	406	Target Neighborhood Hits	588	Shared Neighborhood Hits	80
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SRCA_MOUSE
θ value	0.813845 (rank : 149)	NC score	0.041827 (rank : 223)
Query Neighborhood Hits	406	Target Neighborhood Hits	212	Shared Neighborhood Hits	46
SwissProt Accessions	Q7TQ48, Q8BS43	Gene names	Srl, Sar
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

APBB1_MOUSE
θ value	1.06291 (rank : 150)	NC score	0.051725 (rank : 193)
Query Neighborhood Hits	406	Target Neighborhood Hits	75	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QXJ1, O08642, Q3TPU0, Q8BNF4, Q8BSR9	Gene names	Apbb1, Fe65
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein).

AZI1_HUMAN
θ value	1.06291 (rank : 151)	NC score	0.020588 (rank : 324)
Query Neighborhood Hits	406	Target Neighborhood Hits	1000	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

ELF4_MOUSE
θ value	1.06291 (rank : 152)	NC score	0.020549 (rank : 326)
Query Neighborhood Hits	406	Target Neighborhood Hits	191	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z2U4	Gene names	Elf4, Mef
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-4 (E74-like factor 4) (Myeloid Elf-1-like factor).

FOXJ2_MOUSE
θ value	1.06291 (rank : 153)	NC score	0.007876 (rank : 437)
Query Neighborhood Hits	406	Target Neighborhood Hits	151	Shared Neighborhood Hits	9
SwissProt Accessions	Q9ES18	Gene names	Foxj2, Fhx
Domain Architecture
Description	Forkhead box protein J2 (Fork head homologous X).

GALT5_HUMAN
θ value	1.06291 (rank : 154)	NC score	0.005508 (rank : 461)
Query Neighborhood Hits	406	Target Neighborhood Hits	94	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z7M9, Q9UGK7, Q9UHL6	Gene names	GALNT5
Domain Architecture	No domain graphic available
Description	Polypeptide N-acetylgalactosaminyltransferase 5 (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 5) (UDP- GalNAc:polypeptide N-acetylgalactosaminyltransferase 5) (Polypeptide GalNAc transferase 5) (GalNAc-T5) (pp-GaNTase 5).

GP112_HUMAN
θ value	1.06291 (rank : 155)	NC score	0.025416 (rank : 295)
Query Neighborhood Hits	406	Target Neighborhood Hits	441	Shared Neighborhood Hits	55
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

NCOA1_MOUSE
θ value	1.06291 (rank : 156)	NC score	0.012999 (rank : 394)
Query Neighborhood Hits	406	Target Neighborhood Hits	196	Shared Neighborhood Hits	17
SwissProt Accessions	P70365, P70366, Q61202, Q8CBI9	Gene names	Ncoa1, Src1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (Nuclear receptor coactivator protein 1) (mNRC-1).

NCOR1_HUMAN
θ value	1.06291 (rank : 157)	NC score	0.041543 (rank : 225)
Query Neighborhood Hits	406	Target Neighborhood Hits	577	Shared Neighborhood Hits	93
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

NGEF_HUMAN
θ value	1.06291 (rank : 158)	NC score	0.017802 (rank : 351)
Query Neighborhood Hits	406	Target Neighborhood Hits	166	Shared Neighborhood Hits	13
SwissProt Accessions	Q8N5V2, Q53QQ4, Q53ST7, Q6GMQ5, Q9NQD6	Gene names	NGEF
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

TF2AY_HUMAN
θ value	1.06291 (rank : 159)	NC score	0.046558 (rank : 213)
Query Neighborhood Hits	406	Target Neighborhood Hits	77	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UNN4	Gene names	GTF2A1LF, ALF
Domain Architecture
Description	TFIIA-alpha and beta-like factor (General transcription factor II A, 1-like factor).

TTC1_HUMAN
θ value	1.06291 (rank : 160)	NC score	0.024601 (rank : 303)
Query Neighborhood Hits	406	Target Neighborhood Hits	417	Shared Neighborhood Hits	34
SwissProt Accessions	Q99614, Q9BVT3	Gene names	TTC1, TPR1
Domain Architecture
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

UACA_HUMAN
θ value	1.06291 (rank : 161)	NC score	0.011532 (rank : 410)
Query Neighborhood Hits	406	Target Neighborhood Hits	1622	Shared Neighborhood Hits	71
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

ZN217_HUMAN
θ value	1.06291 (rank : 162)	NC score	0.006457 (rank : 450)
Query Neighborhood Hits	406	Target Neighborhood Hits	905	Shared Neighborhood Hits	44
SwissProt Accessions	O75362	Gene names	ZNF217, ZABC1
Domain Architecture	No domain graphic available
Description	Zinc finger protein 217.

DCP1A_HUMAN
θ value	1.38821 (rank : 163)	NC score	0.039092 (rank : 231)
Query Neighborhood Hits	406	Target Neighborhood Hits	228	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NPI6	Gene names	DCP1A, SMIF
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (Smad4-interacting transcriptional co-activator).

FANCJ_HUMAN
θ value	1.38821 (rank : 164)	NC score	0.021328 (rank : 318)
Query Neighborhood Hits	406	Target Neighborhood Hits	72	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BX63, Q8NCI5	Gene names	BRIP1, BACH1, FANCJ
Domain Architecture	No domain graphic available
Description	Fanconi anemia group J protein (EC 3.6.1.-) (ATP-dependent RNA helicase BRIP1) (Protein FACJ) (BRCA1-interacting protein C-terminal helicase 1) (BRCA1-interacting protein 1) (BRCA1-associated C-terminal helicase 1).

GAB1_HUMAN
θ value	1.38821 (rank : 165)	NC score	0.025091 (rank : 300)
Query Neighborhood Hits	406	Target Neighborhood Hits	279	Shared Neighborhood Hits	29
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

GOGB1_HUMAN
θ value	1.38821 (rank : 166)	NC score	0.016944 (rank : 359)
Query Neighborhood Hits	406	Target Neighborhood Hits	2297	Shared Neighborhood Hits	114
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

HNF1B_HUMAN
θ value	1.38821 (rank : 167)	NC score	0.019233 (rank : 334)
Query Neighborhood Hits	406	Target Neighborhood Hits	80	Shared Neighborhood Hits	11
SwissProt Accessions	P35680	Gene names	TCF2, HNF1B
Domain Architecture
Description	Hepatocyte nuclear factor 1-beta (HNF-1beta) (HNF-1B) (Variant hepatic nuclear factor 1) (VHNF1) (Homeoprotein LFB3) (Transcription factor 2) (TCF-2).

HNF1B_MOUSE
θ value	1.38821 (rank : 168)	NC score	0.018881 (rank : 339)
Query Neighborhood Hits	406	Target Neighborhood Hits	78	Shared Neighborhood Hits	11
SwissProt Accessions	P27889, Q8R162, Q9CS26, Q9R1W1, Q9R1W2, Q9WTL5, Q9WTL6	Gene names	Tcf2, Hnf-1b, Hnf1b
Domain Architecture
Description	Hepatocyte nuclear factor 1-beta (HNF-1beta) (HNF-1B) (Variant hepatic nuclear factor 1) (VHNF1) (Homeoprotein LFB3).

OXR1_MOUSE
θ value	1.38821 (rank : 169)	NC score	0.039902 (rank : 229)
Query Neighborhood Hits	406	Target Neighborhood Hits	516	Shared Neighborhood Hits	82
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

TCAL3_HUMAN
θ value	1.38821 (rank : 170)	NC score	0.047989 (rank : 208)
Query Neighborhood Hits	406	Target Neighborhood Hits	274	Shared Neighborhood Hits	36
SwissProt Accessions	Q969E4	Gene names	TCEAL3
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 3 (TCEA-like protein 3) (Transcription elongation factor S-II protein-like 3).

TDRD5_HUMAN
θ value	1.38821 (rank : 171)	NC score	0.031472 (rank : 267)
Query Neighborhood Hits	406	Target Neighborhood Hits	65	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NAT2, Q5VTV0	Gene names	TDRD5
Domain Architecture
Description	Tudor domain-containing protein 5.

BIN1_HUMAN
θ value	1.81305 (rank : 172)	NC score	0.044137 (rank : 216)
Query Neighborhood Hits	406	Target Neighborhood Hits	335	Shared Neighborhood Hits	51
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

BIN1_MOUSE
θ value	1.81305 (rank : 173)	NC score	0.035763 (rank : 245)
Query Neighborhood Hits	406	Target Neighborhood Hits	283	Shared Neighborhood Hits	41
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

CEP35_HUMAN
θ value	1.81305 (rank : 174)	NC score	0.032010 (rank : 264)
Query Neighborhood Hits	406	Target Neighborhood Hits	811	Shared Neighborhood Hits	73
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

FOXJ2_HUMAN
θ value	1.81305 (rank : 175)	NC score	0.007661 (rank : 439)
Query Neighborhood Hits	406	Target Neighborhood Hits	239	Shared Neighborhood Hits	16
SwissProt Accessions	Q9P0K8, Q96PS9, Q9NSN5	Gene names	FOXJ2, FHX
Domain Architecture
Description	Forkhead box protein J2 (Fork head homologous X).

GAK7_HUMAN
θ value	1.81305 (rank : 176)	NC score	0.009118 (rank : 428)
Query Neighborhood Hits	406	Target Neighborhood Hits	90	Shared Neighborhood Hits	11
SwissProt Accessions	Q96PI4, Q9QC08	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q23.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K18 Gag protein) (HERV-K110 Gag protein) (HERV-K(C1a) Gag protein) [Contains: Matrix protein].

GMPR1_HUMAN
θ value	1.81305 (rank : 177)	NC score	0.018418 (rank : 343)
Query Neighborhood Hits	406	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	P36959, Q96HQ6	Gene names	GMPR, GMPR1
Domain Architecture
Description	GMP reductase 1 (EC 1.7.1.7) (Guanosine 5'-monophosphate oxidoreductase 1) (Guanosine monophosphate reductase 1).

HLX1_MOUSE
θ value	1.81305 (rank : 178)	NC score	0.008275 (rank : 435)
Query Neighborhood Hits	406	Target Neighborhood Hits	362	Shared Neighborhood Hits	12
SwissProt Accessions	Q61670	Gene names	Hlx1, Hlx
Domain Architecture
Description	Homeobox protein HLX1.

LATS2_HUMAN
θ value	1.81305 (rank : 179)	NC score	0.002953 (rank : 475)
Query Neighborhood Hits	406	Target Neighborhood Hits	884	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NRM7, Q9P2X1	Gene names	LATS2, KPM
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein) (Warts-like kinase).

LATS2_MOUSE
θ value	1.81305 (rank : 180)	NC score	0.002311 (rank : 485)
Query Neighborhood Hits	406	Target Neighborhood Hits	879	Shared Neighborhood Hits	23
SwissProt Accessions	Q7TSJ6, Q8CDJ4, Q9JMI3	Gene names	Lats2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein).

MMRN2_HUMAN
θ value	1.81305 (rank : 181)	NC score	0.022515 (rank : 312)
Query Neighborhood Hits	406	Target Neighborhood Hits	400	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H8L6, Q6P2N2	Gene names	MMRN2, EMILIN3
Domain Architecture
Description	Multimerin-2 precursor (EMILIN-3) (Elastin microfibril interface located protein 3) (Elastin microfibril interfacer 3) (EndoGlyx-1 p125/p140 subunit).

MUC1_MOUSE
θ value	1.81305 (rank : 182)	NC score	0.078886 (rank : 96)
Query Neighborhood Hits	406	Target Neighborhood Hits	388	Shared Neighborhood Hits	72
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

MYST3_MOUSE
θ value	1.81305 (rank : 183)	NC score	0.040540 (rank : 228)
Query Neighborhood Hits	406	Target Neighborhood Hits	688	Shared Neighborhood Hits	105
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

PA24F_HUMAN
θ value	1.81305 (rank : 184)	NC score	0.027155 (rank : 285)
Query Neighborhood Hits	406	Target Neighborhood Hits	78	Shared Neighborhood Hits	10
SwissProt Accessions	Q68DD2, Q6ZMC8	Gene names	PLA2G4F
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

PACN2_MOUSE
θ value	1.81305 (rank : 185)	NC score	0.015105 (rank : 377)
Query Neighborhood Hits	406	Target Neighborhood Hits	382	Shared Neighborhood Hits	31
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

PCLO_HUMAN
θ value	1.81305 (rank : 186)	NC score	0.089347 (rank : 77)
Query Neighborhood Hits	406	Target Neighborhood Hits	2046	Shared Neighborhood Hits	178
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

RHBD3_MOUSE
θ value	1.81305 (rank : 187)	NC score	0.033962 (rank : 255)
Query Neighborhood Hits	406	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BP97, Q3U0Y4, Q5SUT5, Q5SUT6, Q5SUT7	Gene names	Rhbdd3
Domain Architecture	No domain graphic available
Description	Rhomboid domain-containing protein 3.

RPTN_MOUSE
θ value	1.81305 (rank : 188)	NC score	0.027150 (rank : 286)
Query Neighborhood Hits	406	Target Neighborhood Hits	650	Shared Neighborhood Hits	47
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

RSF1_HUMAN
θ value	1.81305 (rank : 189)	NC score	0.048725 (rank : 203)
Query Neighborhood Hits	406	Target Neighborhood Hits	539	Shared Neighborhood Hits	78
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

SAS10_MOUSE
θ value	1.81305 (rank : 190)	NC score	0.036628 (rank : 243)
Query Neighborhood Hits	406	Target Neighborhood Hits	81	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JI13, Q3UL95, Q8R5C6, Q9JJ12	Gene names	Crlz1, Crl1, Sas10
Domain Architecture	No domain graphic available
Description	Something about silencing protein 10 (Disrupter of silencing SAS10) (Charged amino acid-rich leucine zipper 1) (Crl-1).

SET1A_HUMAN
θ value	1.81305 (rank : 191)	NC score	0.072898 (rank : 108)
Query Neighborhood Hits	406	Target Neighborhood Hits	690	Shared Neighborhood Hits	103
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

TMF1_HUMAN
θ value	1.81305 (rank : 192)	NC score	0.019373 (rank : 332)
Query Neighborhood Hits	406	Target Neighborhood Hits	987	Shared Neighborhood Hits	63
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

UBP5_MOUSE
θ value	1.81305 (rank : 193)	NC score	0.022210 (rank : 314)
Query Neighborhood Hits	406	Target Neighborhood Hits	106	Shared Neighborhood Hits	11
SwissProt Accessions	P56399	Gene names	Usp5, Isot
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

Z297B_MOUSE
θ value	1.81305 (rank : 194)	NC score	0.001653 (rank : 489)
Query Neighborhood Hits	406	Target Neighborhood Hits	806	Shared Neighborhood Hits	29
SwissProt Accessions	Q9DAI4	Gene names	Znf297b, Kiaa0414, Zfp297b
Domain Architecture
Description	Zinc finger protein 297B.

ZC11A_MOUSE
θ value	1.81305 (rank : 195)	NC score	0.030712 (rank : 269)
Query Neighborhood Hits	406	Target Neighborhood Hits	216	Shared Neighborhood Hits	29
SwissProt Accessions	Q6NZF1, Q6NXW9, Q6PDR6, Q80TU7, Q8C5L5, Q99JN6	Gene names	Zc3h11a, Kiaa0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

BPTF_HUMAN
θ value	2.36792 (rank : 196)	NC score	0.048474 (rank : 205)
Query Neighborhood Hits	406	Target Neighborhood Hits	786	Shared Neighborhood Hits	103
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

CHD9_HUMAN
θ value	2.36792 (rank : 197)	NC score	0.013982 (rank : 386)
Query Neighborhood Hits	406	Target Neighborhood Hits	343	Shared Neighborhood Hits	45
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

DCC_MOUSE
θ value	2.36792 (rank : 198)	NC score	0.005859 (rank : 455)
Query Neighborhood Hits	406	Target Neighborhood Hits	896	Shared Neighborhood Hits	51
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

DGKZ_HUMAN
θ value	2.36792 (rank : 199)	NC score	0.015769 (rank : 371)
Query Neighborhood Hits	406	Target Neighborhood Hits	551	Shared Neighborhood Hits	10
SwissProt Accessions	Q13574, O00542	Gene names	DGKZ, DAGK6
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

EP15R_MOUSE
θ value	2.36792 (rank : 200)	NC score	0.015770 (rank : 370)
Query Neighborhood Hits	406	Target Neighborhood Hits	1135	Shared Neighborhood Hits	76
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

GRIPE_MOUSE
θ value	2.36792 (rank : 201)	NC score	0.021174 (rank : 319)
Query Neighborhood Hits	406	Target Neighborhood Hits	70	Shared Neighborhood Hits	10
SwissProt Accessions	Q6GYP7, Q6GYP6, Q6ZQ28, Q8BNJ5, Q8C9G8, Q8CIW4, Q9JMC4	Gene names	Garnl1, Kiaa0884, Tulip1
Domain Architecture	No domain graphic available
Description	GTPase-activating RapGAP domain-like 1 (GAP-related-interacting partner to E12) (GRIPE) (Tuberin-like protein 1).

K1543_MOUSE
θ value	2.36792 (rank : 202)	NC score	0.026443 (rank : 290)
Query Neighborhood Hits	406	Target Neighborhood Hits	497	Shared Neighborhood Hits	54
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

LAP4_HUMAN
θ value	2.36792 (rank : 203)	NC score	0.005716 (rank : 457)
Query Neighborhood Hits	406	Target Neighborhood Hits	608	Shared Neighborhood Hits	45
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

MAST4_HUMAN
θ value	2.36792 (rank : 204)	NC score	0.007460 (rank : 446)
Query Neighborhood Hits	406	Target Neighborhood Hits	1804	Shared Neighborhood Hits	103
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

MUC13_MOUSE
θ value	2.36792 (rank : 205)	NC score	0.067380 (rank : 120)
Query Neighborhood Hits	406	Target Neighborhood Hits	447	Shared Neighborhood Hits	54
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

NCA11_MOUSE
θ value	2.36792 (rank : 206)	NC score	0.016459 (rank : 365)
Query Neighborhood Hits	406	Target Neighborhood Hits	661	Shared Neighborhood Hits	55
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

PCLO_MOUSE
θ value	2.36792 (rank : 207)	NC score	0.081631 (rank : 93)
Query Neighborhood Hits	406	Target Neighborhood Hits	2275	Shared Neighborhood Hits	173
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PPAC3_MOUSE
θ value	2.36792 (rank : 208)	NC score	0.022105 (rank : 315)
Query Neighborhood Hits	406	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q91WB2	Gene names	Ppapdc3
Domain Architecture	No domain graphic available
Description	Probable lipid phosphate phosphatase PPAPDC3 (EC 3.1.3.-) (Phosphatidic acid phosphatase type 2 domain-containing protein 3).

PRG3_MOUSE
θ value	2.36792 (rank : 209)	NC score	0.021613 (rank : 316)
Query Neighborhood Hits	406	Target Neighborhood Hits	103	Shared Neighborhood Hits	9
SwissProt Accessions	Q9JL95, Q3SXA9	Gene names	Prg3, Mbp2
Domain Architecture	No domain graphic available
Description	Proteoglycan 3 precursor (Eosinophil major basic protein 2).

RAG2_HUMAN
θ value	2.36792 (rank : 210)	NC score	0.034315 (rank : 253)
Query Neighborhood Hits	406	Target Neighborhood Hits	60	Shared Neighborhood Hits	9
SwissProt Accessions	P55895, Q8TBL4	Gene names	RAG2
Domain Architecture
Description	V(D)J recombination-activating protein 2 (RAG-2).

RBM25_HUMAN
θ value	2.36792 (rank : 211)	NC score	0.037630 (rank : 235)
Query Neighborhood Hits	406	Target Neighborhood Hits	682	Shared Neighborhood Hits	68
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

RGS3_HUMAN
θ value	2.36792 (rank : 212)	NC score	0.033737 (rank : 257)
Query Neighborhood Hits	406	Target Neighborhood Hits	1375	Shared Neighborhood Hits	98
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

RPGF6_HUMAN
θ value	2.36792 (rank : 213)	NC score	0.012867 (rank : 395)
Query Neighborhood Hits	406	Target Neighborhood Hits	266	Shared Neighborhood Hits	17
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

SC23B_HUMAN
θ value	2.36792 (rank : 214)	NC score	0.018617 (rank : 341)
Query Neighborhood Hits	406	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	Q15437, Q5W183, Q9BS15, Q9BSI2, Q9H1D7	Gene names	SEC23B
Domain Architecture
Description	Protein transport protein Sec23B (SEC23-related protein B).

SC23B_MOUSE
θ value	2.36792 (rank : 215)	NC score	0.018567 (rank : 342)
Query Neighborhood Hits	406	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D662, Q3U6B3, Q99K49, Q9QZ68	Gene names	Sec23b
Domain Architecture
Description	Protein transport protein Sec23B (SEC23-related protein B).

SEM6A_HUMAN
θ value	2.36792 (rank : 216)	NC score	0.003779 (rank : 471)
Query Neighborhood Hits	406	Target Neighborhood Hits	96	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H2E6, Q9P2H9	Gene names	SEMA6A, KIAA1368
Domain Architecture
Description	Semaphorin-6A precursor (Semaphorin VIA) (Sema VIA) (Semaphorin 6A-1) (SEMA6A-1).

SEPT9_HUMAN
θ value	2.36792 (rank : 217)	NC score	0.019200 (rank : 335)
Query Neighborhood Hits	406	Target Neighborhood Hits	706	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

TAF9B_HUMAN
θ value	2.36792 (rank : 218)	NC score	0.026469 (rank : 289)
Query Neighborhood Hits	406	Target Neighborhood Hits	54	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HBM6, Q9Y2S3	Gene names	TAF9B, TAF9L
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 9B (Transcription initiation factor TFIID subunit 9-like protein) (Transcription- associated factor TAFII31L) (Neuronal cell death-related protein 7) (DN-7).

THUM1_HUMAN
θ value	2.36792 (rank : 219)	NC score	0.029848 (rank : 272)
Query Neighborhood Hits	406	Target Neighborhood Hits	30	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NXG2, Q9BWC3	Gene names	THUMPD1
Domain Architecture
Description	THUMP domain-containing protein 1.

TPR_HUMAN
θ value	2.36792 (rank : 220)	NC score	0.018030 (rank : 348)
Query Neighborhood Hits	406	Target Neighborhood Hits	1921	Shared Neighborhood Hits	124
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

UBP5_HUMAN
θ value	2.36792 (rank : 221)	NC score	0.021066 (rank : 320)
Query Neighborhood Hits	406	Target Neighborhood Hits	109	Shared Neighborhood Hits	11
SwissProt Accessions	P45974, Q96J22	Gene names	USP5, ISOT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

ASTL_HUMAN
θ value	3.0926 (rank : 222)	NC score	0.013675 (rank : 388)
Query Neighborhood Hits	406	Target Neighborhood Hits	252	Shared Neighborhood Hits	25
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

BAZ1A_HUMAN
θ value	3.0926 (rank : 223)	NC score	0.027278 (rank : 284)
Query Neighborhood Hits	406	Target Neighborhood Hits	693	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

CHD9_MOUSE
θ value	3.0926 (rank : 224)	NC score	0.013361 (rank : 391)
Query Neighborhood Hits	406	Target Neighborhood Hits	427	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

DCR1A_HUMAN
θ value	3.0926 (rank : 225)	NC score	0.016780 (rank : 363)
Query Neighborhood Hits	406	Target Neighborhood Hits	43	Shared Neighborhood Hits	6
SwissProt Accessions	Q6PJP8, Q14701, Q6P5Y3, Q6PKL4	Gene names	DCLRE1A, KIAA0086, SNM1, SNM1A
Domain Architecture	No domain graphic available
Description	DNA cross-link repair 1A protein (hSNM1) (hSNM1A).

DMD_HUMAN
θ value	3.0926 (rank : 226)	NC score	0.036739 (rank : 242)
Query Neighborhood Hits	406	Target Neighborhood Hits	1135	Shared Neighborhood Hits	67
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

EHMT2_MOUSE
θ value	3.0926 (rank : 227)	NC score	0.018214 (rank : 347)
Query Neighborhood Hits	406	Target Neighborhood Hits	750	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

EMSY_MOUSE
θ value	3.0926 (rank : 228)	NC score	0.034828 (rank : 251)
Query Neighborhood Hits	406	Target Neighborhood Hits	294	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BMB0, Q5FWK5, Q80XU1, Q8VDW9	Gene names	Emsy
Domain Architecture
Description	Protein EMSY.

ERR1_HUMAN
θ value	3.0926 (rank : 229)	NC score	0.003366 (rank : 472)
Query Neighborhood Hits	406	Target Neighborhood Hits	157	Shared Neighborhood Hits	12
SwissProt Accessions	P11474, Q14514	Gene names	ESRRA, ERR1, ESRL1, NR3B1
Domain Architecture
Description	Steroid hormone receptor ERR1 (Estrogen-related receptor, alpha) (ERR- alpha) (Estrogen receptor-like 1).

F126A_MOUSE
θ value	3.0926 (rank : 230)	NC score	0.024502 (rank : 304)
Query Neighborhood Hits	406	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P9N1, Q99NC4	Gene names	Fam126a, Drctnnb1a
Domain Architecture	No domain graphic available
Description	Protein FAM126A (Down-regulated by CTNNB1 protein A).

GIT1_MOUSE
θ value	3.0926 (rank : 231)	NC score	0.011884 (rank : 406)
Query Neighborhood Hits	406	Target Neighborhood Hits	341	Shared Neighborhood Hits	18
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

IF35_MOUSE
θ value	3.0926 (rank : 232)	NC score	0.027905 (rank : 282)
Query Neighborhood Hits	406	Target Neighborhood Hits	210	Shared Neighborhood Hits	37
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

K0141_MOUSE
θ value	3.0926 (rank : 233)	NC score	0.029153 (rank : 276)
Query Neighborhood Hits	406	Target Neighborhood Hits	21	Shared Neighborhood Hits	6
SwissProt Accessions	Q9DCV6, Q6A0B8	Gene names	Kiaa0141
Domain Architecture
Description	Protein KIAA0141.

LAMA2_MOUSE
θ value	3.0926 (rank : 234)	NC score	0.005674 (rank : 458)
Query Neighborhood Hits	406	Target Neighborhood Hits	1198	Shared Neighborhood Hits	48
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LR37A_HUMAN
θ value	3.0926 (rank : 235)	NC score	0.026533 (rank : 288)
Query Neighborhood Hits	406	Target Neighborhood Hits	720	Shared Neighborhood Hits	68
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

MDC1_HUMAN
θ value	3.0926 (rank : 236)	NC score	0.066431 (rank : 124)
Query Neighborhood Hits	406	Target Neighborhood Hits	1446	Shared Neighborhood Hits	155
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MLL2_HUMAN
θ value	3.0926 (rank : 237)	NC score	0.042525 (rank : 220)
Query Neighborhood Hits	406	Target Neighborhood Hits	1788	Shared Neighborhood Hits	129
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

NRIP1_MOUSE
θ value	3.0926 (rank : 238)	NC score	0.014407 (rank : 383)
Query Neighborhood Hits	406	Target Neighborhood Hits	110	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CBD1, Q8C3Y8, Q9Z2K2	Gene names	Nrip1
Domain Architecture	No domain graphic available
Description	Nuclear receptor-interacting protein 1 (Nuclear factor RIP140) (Receptor-interacting protein 140).

PGCA_MOUSE
θ value	3.0926 (rank : 239)	NC score	0.018885 (rank : 338)
Query Neighborhood Hits	406	Target Neighborhood Hits	643	Shared Neighborhood Hits	56
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

PGCB_HUMAN
θ value	3.0926 (rank : 240)	NC score	0.011711 (rank : 408)
Query Neighborhood Hits	406	Target Neighborhood Hits	478	Shared Neighborhood Hits	42
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

PHLB1_HUMAN
θ value	3.0926 (rank : 241)	NC score	0.017427 (rank : 357)
Query Neighborhood Hits	406	Target Neighborhood Hits	1038	Shared Neighborhood Hits	87
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PZRN3_MOUSE
θ value	3.0926 (rank : 242)	NC score	0.006408 (rank : 451)
Query Neighborhood Hits	406	Target Neighborhood Hits	447	Shared Neighborhood Hits	23
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

RBFAL_MOUSE
θ value	3.0926 (rank : 243)	NC score	0.025289 (rank : 297)
Query Neighborhood Hits	406	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P3B9	Gene names
Domain Architecture	No domain graphic available
Description	Putative ribosome-binding factor A, mitochondrial precursor.

RTN4_MOUSE
θ value	3.0926 (rank : 244)	NC score	0.054675 (rank : 178)
Query Neighborhood Hits	406	Target Neighborhood Hits	341	Shared Neighborhood Hits	57
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

SP1_MOUSE
θ value	3.0926 (rank : 245)	NC score	-0.001207 (rank : 500)
Query Neighborhood Hits	406	Target Neighborhood Hits	730	Shared Neighborhood Hits	28
SwissProt Accessions	O89090, O89087, Q62251, Q64167	Gene names	Sp1
Domain Architecture
Description	Transcription factor Sp1.

SPTA2_HUMAN
θ value	3.0926 (rank : 246)	NC score	0.011892 (rank : 405)
Query Neighborhood Hits	406	Target Neighborhood Hits	888	Shared Neighborhood Hits	40
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

SV2C_HUMAN
θ value	3.0926 (rank : 247)	NC score	0.010860 (rank : 413)
Query Neighborhood Hits	406	Target Neighborhood Hits	124	Shared Neighborhood Hits	11
SwissProt Accessions	Q496J9, Q496K1, Q9UPU8	Gene names	SV2C, KIAA1054
Domain Architecture	No domain graphic available
Description	Synaptic vesicle glycoprotein 2C.

SVIL_MOUSE
θ value	3.0926 (rank : 248)	NC score	0.021385 (rank : 317)
Query Neighborhood Hits	406	Target Neighborhood Hits	439	Shared Neighborhood Hits	49
SwissProt Accessions	Q8K4L3	Gene names	Svil
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

WHRN_MOUSE
θ value	3.0926 (rank : 249)	NC score	0.013532 (rank : 389)
Query Neighborhood Hits	406	Target Neighborhood Hits	412	Shared Neighborhood Hits	37
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

A2BP1_HUMAN
θ value	4.03905 (rank : 250)	NC score	0.005913 (rank : 453)
Query Neighborhood Hits	406	Target Neighborhood Hits	229	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NWB1, Q9NS20	Gene names	A2BP1, A2BP
Domain Architecture
Description	Ataxin-2-binding protein 1.

AKAP4_HUMAN
θ value	4.03905 (rank : 251)	NC score	0.016839 (rank : 362)
Query Neighborhood Hits	406	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	Q5JQC9, O60904, O95246, Q5JQD1, Q5JQD2, Q5JQD3	Gene names	AKAP4, AKAP82
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 4 precursor (Protein kinase A-anchoring protein 4) (PRKA4) (A-kinase anchor protein 82 kDa) (AKAP 82) (hAKAP82) (Major sperm fibrous sheath protein) (HI).

ANR38_MOUSE
θ value	4.03905 (rank : 252)	NC score	0.007647 (rank : 441)
Query Neighborhood Hits	406	Target Neighborhood Hits	512	Shared Neighborhood Hits	30
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

ASPP2_HUMAN
θ value	4.03905 (rank : 253)	NC score	0.014204 (rank : 384)
Query Neighborhood Hits	406	Target Neighborhood Hits	1156	Shared Neighborhood Hits	77
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

BNC2_HUMAN
θ value	4.03905 (rank : 254)	NC score	0.016474 (rank : 364)
Query Neighborhood Hits	406	Target Neighborhood Hits	439	Shared Neighborhood Hits	27
SwissProt Accessions	Q6ZN30, Q6T3A3, Q8NAR2, Q9H6J0, Q9NXV0	Gene names	BNC2
Domain Architecture	No domain graphic available
Description	Zinc finger protein basonuclin-2.

BOK_MOUSE
θ value	4.03905 (rank : 255)	NC score	0.010805 (rank : 414)
Query Neighborhood Hits	406	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	O35425	Gene names	Bok, Mtd
Domain Architecture	No domain graphic available
Description	Bcl-2-related ovarian killer protein (Matador protein) (Apoptosis activator Mtd).

CCD47_HUMAN
θ value	4.03905 (rank : 256)	NC score	0.036885 (rank : 238)
Query Neighborhood Hits	406	Target Neighborhood Hits	119	Shared Neighborhood Hits	13
SwissProt Accessions	Q96A33, Q96D00, Q96JZ7, Q9H3E4, Q9NRG3	Gene names	CCDC47
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor.

CCD82_MOUSE
θ value	4.03905 (rank : 257)	NC score	0.032236 (rank : 261)
Query Neighborhood Hits	406	Target Neighborhood Hits	75	Shared Neighborhood Hits	15
SwissProt Accessions	Q6PG04, Q3V462	Gene names	Ccdc82
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 82.

CENPR_HUMAN
θ value	4.03905 (rank : 258)	NC score	0.014897 (rank : 378)
Query Neighborhood Hits	406	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	Q13352, Q13353, Q5RJ42, Q5RJ44, Q5RJ45, Q7KYX2, Q96CD5, Q9UKB6	Gene names	ITGB3BP, CENPR, NRIF3
Domain Architecture	No domain graphic available
Description	Centromere protein R (CENP-R) (Nuclear receptor-interacting factor 3) (Integrin beta-3-binding protein) (Beta3-endonexin).

CN037_MOUSE
θ value	4.03905 (rank : 259)	NC score	0.025981 (rank : 292)
Query Neighborhood Hits	406	Target Neighborhood Hits	179	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BT18, Q8BFQ7, Q8R1Q5, Q9D6C5	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 homolog precursor.

EAF1_MOUSE
θ value	4.03905 (rank : 260)	NC score	0.016976 (rank : 358)
Query Neighborhood Hits	406	Target Neighborhood Hits	78	Shared Neighborhood Hits	17
SwissProt Accessions	Q9D4C5	Gene names	Eaf1
Domain Architecture	No domain graphic available
Description	ELL-associated factor 1.

ESCO1_HUMAN
θ value	4.03905 (rank : 261)	NC score	0.026283 (rank : 291)
Query Neighborhood Hits	406	Target Neighborhood Hits	361	Shared Neighborhood Hits	49
SwissProt Accessions	Q5FWF5, Q69YG4, Q69YS3, Q6IMD7, Q8N3Z5, Q8NBG2, Q96PX7	Gene names	ESCO1, EFO1, KIAA1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1) (Establishment factor- like protein 1) (EFO1p) (hEFO1) (CTF7 homolog 1).

ESPL1_HUMAN
θ value	4.03905 (rank : 262)	NC score	0.017809 (rank : 350)
Query Neighborhood Hits	406	Target Neighborhood Hits	95	Shared Neighborhood Hits	11
SwissProt Accessions	Q14674	Gene names	ESPL1, ESP1, KIAA0165
Domain Architecture
Description	Separin (EC 3.4.22.49) (Separase) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein).

HIP1R_MOUSE
θ value	4.03905 (rank : 263)	NC score	0.010688 (rank : 415)
Query Neighborhood Hits	406	Target Neighborhood Hits	959	Shared Neighborhood Hits	55
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

LATS1_HUMAN
θ value	4.03905 (rank : 264)	NC score	0.002786 (rank : 480)
Query Neighborhood Hits	406	Target Neighborhood Hits	1057	Shared Neighborhood Hits	48
SwissProt Accessions	O95835, Q6PKD0	Gene names	LATS1, WARTS
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts).

LEUK_MOUSE
θ value	4.03905 (rank : 265)	NC score	0.043825 (rank : 219)
Query Neighborhood Hits	406	Target Neighborhood Hits	147	Shared Neighborhood Hits	32
SwissProt Accessions	P15702	Gene names	Spn
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Ly- 48) (B cell differentiation antigen LP-3) (CD43 antigen).

MAP1A_HUMAN
θ value	4.03905 (rank : 266)	NC score	0.042309 (rank : 221)
Query Neighborhood Hits	406	Target Neighborhood Hits	1626	Shared Neighborhood Hits	143
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MGRN1_HUMAN
θ value	4.03905 (rank : 267)	NC score	0.015511 (rank : 374)
Query Neighborhood Hits	406	Target Neighborhood Hits	192	Shared Neighborhood Hits	11
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

MTG8_HUMAN
θ value	4.03905 (rank : 268)	NC score	0.016292 (rank : 368)
Query Neighborhood Hits	406	Target Neighborhood Hits	87	Shared Neighborhood Hits	10
SwissProt Accessions	Q06455, Q06456, Q14873, Q16239, Q16346, Q16347, Q92479, Q9BRZ0	Gene names	RUNX1T1, AML1T1, CBFA2T1, CDR, ETO, MTG8, ZMYND2
Domain Architecture
Description	Protein CBFA2T1 (Protein MTG8) (Protein ETO) (Eight twenty one protein) (Cyclin-D-related protein) (Zinc finger MYND domain- containing protein 2).

NEB1_HUMAN
θ value	4.03905 (rank : 269)	NC score	0.016914 (rank : 360)
Query Neighborhood Hits	406	Target Neighborhood Hits	829	Shared Neighborhood Hits	59
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

NEK8_HUMAN
θ value	4.03905 (rank : 270)	NC score	0.018235 (rank : 346)
Query Neighborhood Hits	406	Target Neighborhood Hits	872	Shared Neighborhood Hits	21
SwissProt Accessions	Q86SG6, Q2M1S6, Q8NDH1	Gene names	NEK8, JCK, NEK12A
Domain Architecture
Description	Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never in mitosis A-related kinase 8) (NimA-related protein kinase 8) (NIMA-related kinase 12a).

PALM_MOUSE
θ value	4.03905 (rank : 271)	NC score	0.022279 (rank : 313)
Query Neighborhood Hits	406	Target Neighborhood Hits	228	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Z0P4, Q9Z0P3	Gene names	Palm
Domain Architecture
Description	Paralemmin.

PAPOB_MOUSE
θ value	4.03905 (rank : 272)	NC score	0.007592 (rank : 443)
Query Neighborhood Hits	406	Target Neighborhood Hits	25	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WVP6, Q9R1R3	Gene names	Papolb, Papt, Tpap
Domain Architecture
Description	Poly(A) polymerase beta (EC 2.7.7.19) (PAP beta) (Polynucleotide adenylyltransferase beta) (Testis-specific poly(A) polymerase).

PDE4D_MOUSE
θ value	4.03905 (rank : 273)	NC score	0.007638 (rank : 442)
Query Neighborhood Hits	406	Target Neighborhood Hits	98	Shared Neighborhood Hits	16
SwissProt Accessions	Q01063, Q6TRH9, Q8C4Q7, Q8CG05	Gene names	Pde4d
Domain Architecture	No domain graphic available
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4D (EC 3.1.4.17) (DPDE3).

PHLPL_HUMAN
θ value	4.03905 (rank : 274)	NC score	0.001395 (rank : 490)
Query Neighborhood Hits	406	Target Neighborhood Hits	310	Shared Neighborhood Hits	8
SwissProt Accessions	Q6ZVD8, Q9NV17, Q9Y2E3	Gene names	PHLPPL, KIAA0931
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat protein phosphatase-like (EC 3.1.3.16).

REST_MOUSE
θ value	4.03905 (rank : 275)	NC score	0.011942 (rank : 404)
Query Neighborhood Hits	406	Target Neighborhood Hits	1506	Shared Neighborhood Hits	80
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

SETBP_HUMAN
θ value	4.03905 (rank : 276)	NC score	0.033739 (rank : 256)
Query Neighborhood Hits	406	Target Neighborhood Hits	305	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Y6X0, Q9UEF3	Gene names	SETBP1, KIAA0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

SYNJ1_MOUSE
θ value	4.03905 (rank : 277)	NC score	0.033193 (rank : 259)
Query Neighborhood Hits	406	Target Neighborhood Hits	516	Shared Neighborhood Hits	71
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

SYTL5_MOUSE
θ value	4.03905 (rank : 278)	NC score	0.032646 (rank : 260)
Query Neighborhood Hits	406	Target Neighborhood Hits	154	Shared Neighborhood Hits	15
SwissProt Accessions	Q80T23, Q812E5	Gene names	Sytl5, Slp5
Domain Architecture
Description	Synaptotagmin-like protein 5.

TMPS9_HUMAN
θ value	4.03905 (rank : 279)	NC score	0.001123 (rank : 492)
Query Neighborhood Hits	406	Target Neighborhood Hits	276	Shared Neighborhood Hits	12
SwissProt Accessions	Q7Z410, Q6ZND6, Q7Z411	Gene names	TMPRSS9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserase-I) (Polyserine protease 1) [Contains: Serase-1; Serase-2; Serase-3].

UBP33_HUMAN
θ value	4.03905 (rank : 280)	NC score	0.009083 (rank : 429)
Query Neighborhood Hits	406	Target Neighborhood Hits	157	Shared Neighborhood Hits	15
SwissProt Accessions	Q8TEY7, Q8TEY6, Q96AV6, Q9H9F0, Q9UPQ5	Gene names	USP33, KIAA1097, VDU1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 33 (EC 3.1.2.15) (Ubiquitin thioesterase 33) (Ubiquitin-specific-processing protease 33) (Deubiquitinating enzyme 33) (VHL-interacting deubiquitinating enzyme 1).

VLDLR_HUMAN
θ value	4.03905 (rank : 281)	NC score	0.001674 (rank : 488)
Query Neighborhood Hits	406	Target Neighborhood Hits	383	Shared Neighborhood Hits	9
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

XRCC1_MOUSE
θ value	4.03905 (rank : 282)	NC score	0.037827 (rank : 233)
Query Neighborhood Hits	406	Target Neighborhood Hits	242	Shared Neighborhood Hits	37
SwissProt Accessions	Q60596, Q3THC5, Q5U435, Q7TNQ5	Gene names	Xrcc1, Xrcc-1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

YES_HUMAN
θ value	4.03905 (rank : 283)	NC score	-0.004733 (rank : 505)
Query Neighborhood Hits	406	Target Neighborhood Hits	1059	Shared Neighborhood Hits	25
SwissProt Accessions	P07947	Gene names	YES1, YES
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

ZN509_MOUSE
θ value	4.03905 (rank : 284)	NC score	0.000306 (rank : 496)
Query Neighborhood Hits	406	Target Neighborhood Hits	990	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BXX2, Q8CID4, Q8K2Z6	Gene names	Znf509, Zfp509
Domain Architecture	No domain graphic available
Description	Zinc finger protein 509.

ZN628_MOUSE
θ value	4.03905 (rank : 285)	NC score	-0.000063 (rank : 497)
Query Neighborhood Hits	406	Target Neighborhood Hits	815	Shared Neighborhood Hits	30
SwissProt Accessions	Q8CJ78, Q3U2L5, Q6P5B3	Gene names	Znf628, Zec, Zfp628
Domain Architecture	No domain graphic available
Description	Zinc finger protein 628 (Zinc finger protein expressed in embryonal cells and certain adult organs).

ANLN_MOUSE
θ value	5.27518 (rank : 286)	NC score	0.026851 (rank : 287)
Query Neighborhood Hits	406	Target Neighborhood Hits	297	Shared Neighborhood Hits	25
SwissProt Accessions	Q8K298, Q8BL79, Q8BLB3, Q8K2N0, Q9CUY0	Gene names	Anln
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

ATF4_MOUSE
θ value	5.27518 (rank : 287)	NC score	0.017450 (rank : 356)
Query Neighborhood Hits	406	Target Neighborhood Hits	102	Shared Neighborhood Hits	12
SwissProt Accessions	Q06507, Q61906	Gene names	Atf4
Domain Architecture	No domain graphic available
Description	Cyclic AMP-dependent transcription factor ATF-4 (C/EBP-related ATF) (C/ATF) (TAXREB67 homolog).

CCHCR_HUMAN
θ value	5.27518 (rank : 288)	NC score	0.011834 (rank : 407)
Query Neighborhood Hits	406	Target Neighborhood Hits	717	Shared Neighborhood Hits	42
SwissProt Accessions	Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2	Gene names	CCHCR1, C6orf18, HCR
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8).

CFDP1_HUMAN
θ value	5.27518 (rank : 289)	NC score	0.030897 (rank : 268)
Query Neighborhood Hits	406	Target Neighborhood Hits	80	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UEE9, O00393, O00404, Q9UEF0, Q9UEF1, Q9UEF8	Gene names	CFDP1, BCNT
Domain Architecture	No domain graphic available
Description	Craniofacial development protein 1 (Bucentaur).

CSTFT_MOUSE
θ value	5.27518 (rank : 290)	NC score	0.005036 (rank : 465)
Query Neighborhood Hits	406	Target Neighborhood Hits	356	Shared Neighborhood Hits	16
SwissProt Accessions	Q8C7E9, Q6A016, Q8BHH7, Q8C3W7, Q8R2Y1, Q9EPU3	Gene names	Cstf2t, Kiaa0689
Domain Architecture	No domain graphic available
Description	Cleavage stimulation factor 64 kDa subunit, tau variant (CSTF 64 kDa subunit, tau variant) (CF-1 64 kDa subunit, tau variant) (TauCstF-64).

CT054_MOUSE
θ value	5.27518 (rank : 291)	NC score	0.007506 (rank : 445)
Query Neighborhood Hits	406	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D6X5, Q8CE36, Q91WB9	Gene names
Domain Architecture
Description	Protein C20orf54 homolog precursor.

DBND2_MOUSE
θ value	5.27518 (rank : 292)	NC score	0.012829 (rank : 396)
Query Neighborhood Hits	406	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CRD4	Gene names	Dbndd2, D2Bwg0891e
Domain Architecture
Description	Dysbindin domain-containing protein 2.

EF2K_HUMAN
θ value	5.27518 (rank : 293)	NC score	0.018996 (rank : 337)
Query Neighborhood Hits	406	Target Neighborhood Hits	32	Shared Neighborhood Hits	8
SwissProt Accessions	O00418	Gene names	EEF2K
Domain Architecture
Description	Elongation factor 2 kinase (EC 2.7.11.20) (eEF-2 kinase) (eEF-2K) (Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase).

EF2K_MOUSE
θ value	5.27518 (rank : 294)	NC score	0.020985 (rank : 321)
Query Neighborhood Hits	406	Target Neighborhood Hits	33	Shared Neighborhood Hits	9
SwissProt Accessions	O08796	Gene names	Eef2k
Domain Architecture
Description	Elongation factor 2 kinase (EC 2.7.11.20) (eEF-2 kinase) (eEF-2K) (Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase).

EP400_MOUSE
θ value	5.27518 (rank : 295)	NC score	0.015404 (rank : 375)
Query Neighborhood Hits	406	Target Neighborhood Hits	592	Shared Neighborhood Hits	68
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

EPN2_HUMAN
θ value	5.27518 (rank : 296)	NC score	0.010126 (rank : 418)
Query Neighborhood Hits	406	Target Neighborhood Hits	156	Shared Neighborhood Hits	19
SwissProt Accessions	O95208, O95207, Q9H7Z2, Q9UPT7	Gene names	EPN2, KIAA1065
Domain Architecture
Description	Epsin-2 (EPS-15-interacting protein 2).

GTSE1_MOUSE
θ value	5.27518 (rank : 297)	NC score	0.024321 (rank : 305)
Query Neighborhood Hits	406	Target Neighborhood Hits	245	Shared Neighborhood Hits	39
SwissProt Accessions	Q8R080, O89015, Q9CSG9	Gene names	Gtse1, B99
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (Gtse-1) (B99 protein).

HUNK_HUMAN
θ value	5.27518 (rank : 298)	NC score	-0.002510 (rank : 501)
Query Neighborhood Hits	406	Target Neighborhood Hits	884	Shared Neighborhood Hits	21
SwissProt Accessions	P57058	Gene names	HUNK, MAKV
Domain Architecture
Description	Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (Serine/threonine-protein kinase MAK-V) (B19).

ITF2_HUMAN
θ value	5.27518 (rank : 299)	NC score	0.013696 (rank : 387)
Query Neighborhood Hits	406	Target Neighborhood Hits	168	Shared Neighborhood Hits	18
SwissProt Accessions	P15884, Q15439, Q15440	Gene names	TCF4, ITF2, SEF2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (SL3-3 enhancer factor 2) (SEF-2).

ITF2_MOUSE
θ value	5.27518 (rank : 300)	NC score	0.016457 (rank : 366)
Query Neighborhood Hits	406	Target Neighborhood Hits	154	Shared Neighborhood Hits	19
SwissProt Accessions	Q60722, Q60721, Q62211, Q64072, Q80UE8	Gene names	Tcf4, Itf2, Sef2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2) (Class A helix-loop-helix transcription factor ME2).

LAMP3_MOUSE
θ value	5.27518 (rank : 301)	NC score	0.009555 (rank : 421)
Query Neighborhood Hits	406	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q7TST5, Q8C1F6	Gene names	Lamp3
Domain Architecture	No domain graphic available
Description	Lysosome-associated membrane glycoprotein 3 precursor (LAMP-3) (Lysosomal-associated membrane protein 3) (DC-lysosome-associated membrane glycoprotein) (DC LAMP) (CD208 antigen).

LARP1_HUMAN
θ value	5.27518 (rank : 302)	NC score	0.027697 (rank : 283)
Query Neighborhood Hits	406	Target Neighborhood Hits	242	Shared Neighborhood Hits	32
SwissProt Accessions	Q6PKG0, O94836, Q8N4M2, Q8NB73, Q9UFD7	Gene names	LARP1, KIAA0731, LARP
Domain Architecture	No domain graphic available
Description	La-related protein 1 (La ribonucleoprotein domain family member 1).

LRC50_HUMAN
θ value	5.27518 (rank : 303)	NC score	0.013376 (rank : 390)
Query Neighborhood Hits	406	Target Neighborhood Hits	275	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NEP3, Q69YI8, Q69YJ0, Q96LP3	Gene names	LRRC50
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 50.

MAVS_MOUSE
θ value	5.27518 (rank : 304)	NC score	0.025096 (rank : 299)
Query Neighborhood Hits	406	Target Neighborhood Hits	170	Shared Neighborhood Hits	36
SwissProt Accessions	Q8VCF0	Gene names	Mavs, Ips1, Visa
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif).

MTG8_MOUSE
θ value	5.27518 (rank : 305)	NC score	0.014751 (rank : 382)
Query Neighborhood Hits	406	Target Neighborhood Hits	83	Shared Neighborhood Hits	9
SwissProt Accessions	Q61909	Gene names	Runx1t1, Cbfa2t1, Cbfa2t1h, Mtg8
Domain Architecture
Description	Protein CBFA2T1 (Protein MTG8).

NEUM_HUMAN
θ value	5.27518 (rank : 306)	NC score	0.052938 (rank : 185)
Query Neighborhood Hits	406	Target Neighborhood Hits	132	Shared Neighborhood Hits	40
SwissProt Accessions	P17677	Gene names	GAP43
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (PP46) (Neural phosphoprotein B-50).

NFASC_HUMAN
θ value	5.27518 (rank : 307)	NC score	0.005147 (rank : 464)
Query Neighborhood Hits	406	Target Neighborhood Hits	497	Shared Neighborhood Hits	26
SwissProt Accessions	O94856, Q5T2F0, Q5T2F1, Q5T2F2, Q5T2F3, Q5T2F4, Q5T2F5, Q5T2F6, Q5T2F7, Q5T2F9, Q5T2G0, Q5W9F8, Q68DH3, Q6ZQV6, Q7Z3K1, Q96HT1, Q96K50	Gene names	NFASC, KIAA0756
Domain Architecture
Description	Neurofascin precursor.

NFASC_MOUSE
θ value	5.27518 (rank : 308)	NC score	0.005574 (rank : 459)
Query Neighborhood Hits	406	Target Neighborhood Hits	475	Shared Neighborhood Hits	25
SwissProt Accessions	Q810U3	Gene names	Nfasc
Domain Architecture
Description	Neurofascin precursor.

NIPBL_HUMAN
θ value	5.27518 (rank : 309)	NC score	0.047703 (rank : 209)
Query Neighborhood Hits	406	Target Neighborhood Hits	1311	Shared Neighborhood Hits	129
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

NU153_HUMAN
θ value	5.27518 (rank : 310)	NC score	0.020788 (rank : 322)
Query Neighborhood Hits	406	Target Neighborhood Hits	227	Shared Neighborhood Hits	30
SwissProt Accessions	P49790	Gene names	NUP153
Domain Architecture
Description	Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin).

NUPL_MOUSE
θ value	5.27518 (rank : 311)	NC score	0.016229 (rank : 369)
Query Neighborhood Hits	406	Target Neighborhood Hits	113	Shared Neighborhood Hits	16
SwissProt Accessions	Q8K2K6, O70448, Q8BQL5, Q8CDK9	Gene names	Hrb, Rip
Domain Architecture
Description	Nucleoporin-like protein RIP (HIV-1 Rev-binding protein homolog).

OXRP_HUMAN
θ value	5.27518 (rank : 312)	NC score	0.014859 (rank : 379)
Query Neighborhood Hits	406	Target Neighborhood Hits	544	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

PDE4D_HUMAN
θ value	5.27518 (rank : 313)	NC score	0.007530 (rank : 444)
Query Neighborhood Hits	406	Target Neighborhood Hits	122	Shared Neighborhood Hits	21
SwissProt Accessions	Q08499, O43433, Q13549, Q13550, Q13551, Q7Z2L8, Q8IV84, Q8IVA9, Q8IVD2, Q8IVD3, Q9HCX7	Gene names	PDE4D
Domain Architecture
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4D (EC 3.1.4.17) (DPDE3) (PDE43).

RFTN1_MOUSE
θ value	5.27518 (rank : 314)	NC score	0.008625 (rank : 432)
Query Neighborhood Hits	406	Target Neighborhood Hits	36	Shared Neighborhood Hits	5
SwissProt Accessions	Q6A0D4, Q3U654, Q3U8P6, Q80US1	Gene names	Rftn1, Kiaa0084
Domain Architecture	No domain graphic available
Description	Raftlin (Raft-linking protein).

RFWD2_MOUSE
θ value	5.27518 (rank : 315)	NC score	0.000778 (rank : 494)
Query Neighborhood Hits	406	Target Neighborhood Hits	535	Shared Neighborhood Hits	12
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

SEMG1_HUMAN
θ value	5.27518 (rank : 316)	NC score	0.027993 (rank : 281)
Query Neighborhood Hits	406	Target Neighborhood Hits	200	Shared Neighborhood Hits	25
SwissProt Accessions	P04279, Q6X4I9, Q6Y809, Q6Y822, Q6Y823, Q86U64, Q96QM3	Gene names	SEMG1, SEMG
Domain Architecture
Description	Semenogelin-1 precursor (Semenogelin I) (SGI) [Contains: Alpha- inhibin-92; Alpha-inhibin-31; Seminal basic protein].

SETBP_MOUSE
θ value	5.27518 (rank : 317)	NC score	0.035846 (rank : 244)
Query Neighborhood Hits	406	Target Neighborhood Hits	352	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

SMCE1_MOUSE
θ value	5.27518 (rank : 318)	NC score	0.024061 (rank : 308)
Query Neighborhood Hits	406	Target Neighborhood Hits	409	Shared Neighborhood Hits	42
SwissProt Accessions	O54941, Q8BPD9	Gene names	Smarce1, Baf57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator chromatin subfamily E member 1 (BRG1-associated factor 57).

STK10_HUMAN
θ value	5.27518 (rank : 319)	NC score	0.000763 (rank : 495)
Query Neighborhood Hits	406	Target Neighborhood Hits	1921	Shared Neighborhood Hits	98
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

TACT_HUMAN
θ value	5.27518 (rank : 320)	NC score	0.025288 (rank : 298)
Query Neighborhood Hits	406	Target Neighborhood Hits	100	Shared Neighborhood Hits	15
SwissProt Accessions	P40200	Gene names	CD96
Domain Architecture	No domain graphic available
Description	T-cell surface protein tactile precursor (T cell-activated increased late expression protein) (CD96 antigen).

ASPM_MOUSE
θ value	6.88961 (rank : 321)	NC score	0.009251 (rank : 424)
Query Neighborhood Hits	406	Target Neighborhood Hits	150	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CJ27, O88482, Q8BJI8, Q8BKT4	Gene names	Aspm, Calmbp1, Sha1
Domain Architecture
Description	Abnormal spindle-like microcephaly-associated protein homolog (Calmodulin-binding protein 1) (Spindle and hydroxyurea checkpoint abnormal protein) (Calmodulin-binding protein Sha1).

CCD82_HUMAN
θ value	6.88961 (rank : 322)	NC score	0.034939 (rank : 250)
Query Neighborhood Hits	406	Target Neighborhood Hits	137	Shared Neighborhood Hits	35
SwissProt Accessions	Q8N4S0, Q9H2Q5, Q9H5E3	Gene names	CCDC82
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 82.

CFDP1_MOUSE
θ value	6.88961 (rank : 323)	NC score	0.037350 (rank : 236)
Query Neighborhood Hits	406	Target Neighborhood Hits	64	Shared Neighborhood Hits	17
SwissProt Accessions	O88271, O70565, Q9JMA5	Gene names	Cfdp1, Bcnt, Cfdp, Cp27
Domain Architecture	No domain graphic available
Description	Craniofacial development protein 1 (Bucentaur) (27 kDa craniofacial protein) (Protein Cp27).

DMP1_MOUSE
θ value	6.88961 (rank : 324)	NC score	0.074009 (rank : 105)
Query Neighborhood Hits	406	Target Neighborhood Hits	498	Shared Neighborhood Hits	98
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

DUS7_HUMAN
θ value	6.88961 (rank : 325)	NC score	0.002115 (rank : 486)
Query Neighborhood Hits	406	Target Neighborhood Hits	69	Shared Neighborhood Hits	5
SwissProt Accessions	Q16829, Q8NFJ0	Gene names	DUSP7, PYST2
Domain Architecture
Description	Dual specificity protein phosphatase 7 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PYST2).

F10A4_HUMAN
θ value	6.88961 (rank : 326)	NC score	0.022755 (rank : 311)
Query Neighborhood Hits	406	Target Neighborhood Hits	249	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IZP2	Gene names	FAM10A4
Domain Architecture	No domain graphic available
Description	Protein FAM10A4.

F126A_HUMAN
θ value	6.88961 (rank : 327)	NC score	0.018831 (rank : 340)
Query Neighborhood Hits	406	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BYI3, Q6N010, Q75MR4, Q7LDZ4, Q96MX1, Q96NQ6	Gene names	FAM126A, DRCTNNB1A
Domain Architecture	No domain graphic available
Description	Protein FAM126A (Down-regulated by CTNNB1 protein A).

GCC2_HUMAN
θ value	6.88961 (rank : 328)	NC score	0.009120 (rank : 427)
Query Neighborhood Hits	406	Target Neighborhood Hits	1558	Shared Neighborhood Hits	75
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

GRIPE_HUMAN
θ value	6.88961 (rank : 329)	NC score	0.016299 (rank : 367)
Query Neighborhood Hits	406	Target Neighborhood Hits	69	Shared Neighborhood Hits	7
SwissProt Accessions	Q6GYQ0, O94960, Q6GYP9, Q6ZT23, Q86YF3, Q86YF5, Q8ND69	Gene names	GARNL1, KIAA0884, TULIP1
Domain Architecture	No domain graphic available
Description	GTPase-activating Rap/Ran-GAP domain-like 1 (GAP-related-interacting partner to E12) (GRIPE) (Tuberin-like protein 1).

HLX1_HUMAN
θ value	6.88961 (rank : 330)	NC score	0.005885 (rank : 454)
Query Neighborhood Hits	406	Target Neighborhood Hits	370	Shared Neighborhood Hits	14
SwissProt Accessions	Q14774, Q15988	Gene names	HLX1
Domain Architecture
Description	Homeobox protein HLX1 (Homeobox protein HB24).

JIP4_MOUSE
θ value	6.88961 (rank : 331)	NC score	0.012396 (rank : 402)
Query Neighborhood Hits	406	Target Neighborhood Hits	593	Shared Neighborhood Hits	45
SwissProt Accessions	Q58A65, Q3UH77, Q3UHF0, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2	Gene names	Spag9, Jip4, Jsap2, Kiaa0516, Mapk8ip4
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (JNK/SAPK-associated protein 2) (JSAP2).

KPB1_HUMAN
θ value	6.88961 (rank : 332)	NC score	0.006526 (rank : 448)
Query Neighborhood Hits	406	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	P46020, Q2M3D7	Gene names	PHKA1, PHKA
Domain Architecture
Description	Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform (Phosphorylase kinase alpha M subunit).

KPB1_MOUSE
θ value	6.88961 (rank : 333)	NC score	0.006510 (rank : 449)
Query Neighborhood Hits	406	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	P18826	Gene names	Phka1
Domain Architecture
Description	Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform (Phosphorylase kinase alpha M subunit).

LAMA2_HUMAN
θ value	6.88961 (rank : 334)	NC score	0.002515 (rank : 483)
Query Neighborhood Hits	406	Target Neighborhood Hits	1092	Shared Neighborhood Hits	39
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMB1_HUMAN
θ value	6.88961 (rank : 335)	NC score	0.002835 (rank : 479)
Query Neighborhood Hits	406	Target Neighborhood Hits	1018	Shared Neighborhood Hits	40
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LPIN1_MOUSE
θ value	6.88961 (rank : 336)	NC score	0.009289 (rank : 423)
Query Neighborhood Hits	406	Target Neighborhood Hits	85	Shared Neighborhood Hits	11
SwissProt Accessions	Q91ZP3, Q9CQI2, Q9JLG6	Gene names	Lpin1, Fld
Domain Architecture
Description	Lipin-1 (Fatty liver dystrophy protein).

MARK1_HUMAN
θ value	6.88961 (rank : 337)	NC score	-0.003959 (rank : 504)
Query Neighborhood Hits	406	Target Neighborhood Hits	887	Shared Neighborhood Hits	18
SwissProt Accessions	Q9P0L2, Q5VTF9, Q5VTG0, Q96SW9, Q9P251	Gene names	MARK1, KIAA1477, MARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MARK1 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 1).

MARK4_MOUSE
θ value	6.88961 (rank : 338)	NC score	-0.002912 (rank : 503)
Query Neighborhood Hits	406	Target Neighborhood Hits	898	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CIP4, Q80T81	Gene names	Mark4, Kiaa1860
Domain Architecture	No domain graphic available
Description	MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1).

MINT_MOUSE
θ value	6.88961 (rank : 339)	NC score	0.035659 (rank : 246)
Query Neighborhood Hits	406	Target Neighborhood Hits	1514	Shared Neighborhood Hits	148
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NCOA2_MOUSE
θ value	6.88961 (rank : 340)	NC score	0.011613 (rank : 409)
Query Neighborhood Hits	406	Target Neighborhood Hits	281	Shared Neighborhood Hits	29
SwissProt Accessions	Q61026, O09001, P97759	Gene names	Ncoa2, Grip1, Tif2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1).

NF2L2_HUMAN
θ value	6.88961 (rank : 341)	NC score	0.009863 (rank : 420)
Query Neighborhood Hits	406	Target Neighborhood Hits	109	Shared Neighborhood Hits	14
SwissProt Accessions	Q16236, Q96F71	Gene names	NFE2L2, NRF2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2) (HEBP1).

NU205_HUMAN
θ value	6.88961 (rank : 342)	NC score	0.015122 (rank : 376)
Query Neighborhood Hits	406	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q92621, Q86YC1	Gene names	NUP205, C7orf14, KIAA0225
Domain Architecture	No domain graphic available
Description	Nuclear pore complex protein Nup205 (Nucleoporin Nup205) (205 kDa nucleoporin).

PP2CA_HUMAN
θ value	6.88961 (rank : 343)	NC score	0.004296 (rank : 467)
Query Neighborhood Hits	406	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	P35813, O75551	Gene names	PPM1A, PPPM1A
Domain Architecture
Description	Protein phosphatase 2C isoform alpha (EC 3.1.3.16) (PP2C-alpha) (IA) (Protein phosphatase 1A).

PRG3_HUMAN
θ value	6.88961 (rank : 344)	NC score	0.014851 (rank : 380)
Query Neighborhood Hits	406	Target Neighborhood Hits	74	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y2Y8	Gene names	PRG3, MBPH
Domain Architecture	No domain graphic available
Description	Proteoglycan 3 precursor (Eosinophil major basic protein homolog) (Prepro-major basic protein homolog) (Prepro-MBPH).

PTN4_HUMAN
θ value	6.88961 (rank : 345)	NC score	0.005540 (rank : 460)
Query Neighborhood Hits	406	Target Neighborhood Hits	303	Shared Neighborhood Hits	16
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

RBP24_HUMAN
θ value	6.88961 (rank : 346)	NC score	0.009035 (rank : 430)
Query Neighborhood Hits	406	Target Neighborhood Hits	1559	Shared Neighborhood Hits	73
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

RD23B_MOUSE
θ value	6.88961 (rank : 347)	NC score	0.035580 (rank : 247)
Query Neighborhood Hits	406	Target Neighborhood Hits	189	Shared Neighborhood Hits	47
SwissProt Accessions	P54728	Gene names	Rad23b, Mhr23b
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (mHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

S4A7_MOUSE
θ value	6.88961 (rank : 348)	NC score	0.004541 (rank : 466)
Query Neighborhood Hits	406	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BTY2, Q3U5H7	Gene names	Slc4a7, Nbc3
Domain Architecture	No domain graphic available
Description	Sodium bicarbonate cotransporter 3 (Solute carrier family 4 member 7).

SALL3_HUMAN
θ value	6.88961 (rank : 349)	NC score	0.002849 (rank : 477)
Query Neighborhood Hits	406	Target Neighborhood Hits	1066	Shared Neighborhood Hits	65
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

SIP1_HUMAN
θ value	6.88961 (rank : 350)	NC score	0.003350 (rank : 473)
Query Neighborhood Hits	406	Target Neighborhood Hits	832	Shared Neighborhood Hits	50
SwissProt Accessions	O60315, Q9UED1	Gene names	ZFHX1B, KIAA0569, SIP1, ZFX1B
Domain Architecture
Description	Zinc finger homeobox protein 1b (Smad-interacting protein 1) (SMADIP1).

SIP1_MOUSE
θ value	6.88961 (rank : 351)	NC score	0.002843 (rank : 478)
Query Neighborhood Hits	406	Target Neighborhood Hits	870	Shared Neighborhood Hits	46
SwissProt Accessions	Q9R0G7	Gene names	Zfhx1b, Sip1, Zfx1b
Domain Architecture
Description	Zinc finger homeobox protein 1b (Smad-interacting protein 1).

SMG5_HUMAN
θ value	6.88961 (rank : 352)	NC score	0.012719 (rank : 398)
Query Neighborhood Hits	406	Target Neighborhood Hits	180	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UPR3, Q5QJE7, Q8IXC0, Q8IY09, Q96IJ7	Gene names	SMG5, EST1B, KIAA1089
Domain Architecture	No domain graphic available
Description	Protein SMG5 (SMG-5 homolog) (EST1-like protein B) (LPTS-interacting protein) (LPTS-RP1).

STAM2_MOUSE
θ value	6.88961 (rank : 353)	NC score	0.006610 (rank : 447)
Query Neighborhood Hits	406	Target Neighborhood Hits	285	Shared Neighborhood Hits	14
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

SYNJ1_HUMAN
θ value	6.88961 (rank : 354)	NC score	0.032120 (rank : 263)
Query Neighborhood Hits	406	Target Neighborhood Hits	498	Shared Neighborhood Hits	69
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

TCOF_HUMAN
θ value	6.88961 (rank : 355)	NC score	0.068628 (rank : 113)
Query Neighborhood Hits	406	Target Neighborhood Hits	543	Shared Neighborhood Hits	97
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

TMM29_HUMAN
θ value	6.88961 (rank : 356)	NC score	0.025378 (rank : 296)
Query Neighborhood Hits	406	Target Neighborhood Hits	40	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NDB6, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q9UI49	Gene names	TMEM29
Domain Architecture	No domain graphic available
Description	Transmembrane protein 29.

TRML2_HUMAN
θ value	6.88961 (rank : 357)	NC score	0.009520 (rank : 422)
Query Neighborhood Hits	406	Target Neighborhood Hits	54	Shared Neighborhood Hits	5
SwissProt Accessions	Q5T2D2, Q8IWY0, Q9H8E9	Gene names	TREML2, C6orf76, TLT2
Domain Architecture	No domain graphic available
Description	Trem-like transcript 2 protein precursor (TLT-2) (Triggering receptor expressed on myeloid cells-like protein 2).

TTC1_MOUSE
θ value	6.88961 (rank : 358)	NC score	0.014789 (rank : 381)
Query Neighborhood Hits	406	Target Neighborhood Hits	145	Shared Neighborhood Hits	11
SwissProt Accessions	Q91Z38, Q3TLM0	Gene names	Ttc1
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

ZBT10_HUMAN
θ value	6.88961 (rank : 359)	NC score	-0.000099 (rank : 498)
Query Neighborhood Hits	406	Target Neighborhood Hits	831	Shared Neighborhood Hits	23
SwissProt Accessions	Q96DT7, Q86W96, Q8IXI9, Q96MH9	Gene names	ZBTB10, RINZF, RINZFC
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 10 (Zinc finger protein RIN ZF).

ZCH11_HUMAN
θ value	6.88961 (rank : 360)	NC score	0.019886 (rank : 329)
Query Neighborhood Hits	406	Target Neighborhood Hits	278	Shared Neighborhood Hits	34
SwissProt Accessions	Q5TAX3, Q12764, Q5TAX4, Q86XZ3	Gene names	ZCCHC11, KIAA0191
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 11.

AMOL1_MOUSE
θ value	8.99809 (rank : 361)	NC score	0.013194 (rank : 392)
Query Neighborhood Hits	406	Target Neighborhood Hits	445	Shared Neighborhood Hits	39
SwissProt Accessions	Q9D4H4, Q571F1	Gene names	Amotl1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

AMOL2_HUMAN
θ value	8.99809 (rank : 362)	NC score	0.009027 (rank : 431)
Query Neighborhood Hits	406	Target Neighborhood Hits	603	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Y2J4, Q53EP1, Q96F99, Q9UKB4	Gene names	AMOTL2, KIAA0989
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2 (Leman coiled-coil protein) (LCCP).

ATBF1_HUMAN
θ value	8.99809 (rank : 363)	NC score	0.009225 (rank : 425)
Query Neighborhood Hits	406	Target Neighborhood Hits	1547	Shared Neighborhood Hits	101
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

BNC2_MOUSE
θ value	8.99809 (rank : 364)	NC score	0.012775 (rank : 397)
Query Neighborhood Hits	406	Target Neighborhood Hits	456	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BMQ3, Q6T3A4	Gene names	Bnc2
Domain Architecture	No domain graphic available
Description	Zinc finger protein basonuclin-2.

BUB1_HUMAN
θ value	8.99809 (rank : 365)	NC score	0.007775 (rank : 438)
Query Neighborhood Hits	406	Target Neighborhood Hits	543	Shared Neighborhood Hits	28
SwissProt Accessions	O43683, O43430, O43643, O60626	Gene names	BUB1, BUB1L
Domain Architecture
Description	Mitotic checkpoint serine/threonine-protein kinase BUB1 (EC 2.7.11.1) (hBUB1) (BUB1A).

CDC27_HUMAN
θ value	8.99809 (rank : 366)	NC score	0.010047 (rank : 419)
Query Neighborhood Hits	406	Target Neighborhood Hits	139	Shared Neighborhood Hits	16
SwissProt Accessions	P30260, Q16349, Q96F35	Gene names	CDC27
Domain Architecture
Description	Cell division cycle protein 27 homolog (CDC27Hs) (H-NUC).

CDN1B_MOUSE
θ value	8.99809 (rank : 367)	NC score	0.009120 (rank : 426)
Query Neighborhood Hits	406	Target Neighborhood Hits	25	Shared Neighborhood Hits	6
SwissProt Accessions	P46414	Gene names	Cdkn1b
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1B (Cyclin-dependent kinase inhibitor p27) (p27Kip1).

CIC_HUMAN
θ value	8.99809 (rank : 368)	NC score	0.028010 (rank : 280)
Query Neighborhood Hits	406	Target Neighborhood Hits	992	Shared Neighborhood Hits	91
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CR025_HUMAN
θ value	8.99809 (rank : 369)	NC score	0.023133 (rank : 310)
Query Neighborhood Hits	406	Target Neighborhood Hits	56	Shared Neighborhood Hits	18
SwissProt Accessions	Q96B23, Q5XG78, Q6N058, Q86TB5, Q8TCQ5	Gene names	C18orf25
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf25.

CR025_MOUSE
θ value	8.99809 (rank : 370)	NC score	0.020584 (rank : 325)
Query Neighborhood Hits	406	Target Neighborhood Hits	36	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BH50, Q3TQ72, Q8BU43	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf25 homolog.

DIAP3_MOUSE
θ value	8.99809 (rank : 371)	NC score	0.008526 (rank : 434)
Query Neighborhood Hits	406	Target Neighborhood Hits	221	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z207	Gene names	Diaph3, Diap3
Domain Architecture
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3) (mDIA2) (p134mDIA2).

DNL4_HUMAN
θ value	8.99809 (rank : 372)	NC score	0.008089 (rank : 436)
Query Neighborhood Hits	406	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	P49917, Q8IY66, Q8TEU5	Gene names	LIG4
Domain Architecture
Description	DNA ligase 4 (EC 6.5.1.1) (DNA ligase IV) (Polydeoxyribonucleotide synthase [ATP] 4).

ENTK_MOUSE
θ value	8.99809 (rank : 373)	NC score	-0.002726 (rank : 502)
Query Neighborhood Hits	406	Target Neighborhood Hits	338	Shared Neighborhood Hits	8
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

FMN2_MOUSE
θ value	8.99809 (rank : 374)	NC score	0.017924 (rank : 349)
Query Neighborhood Hits	406	Target Neighborhood Hits	349	Shared Neighborhood Hits	39
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

HAT1_HUMAN
θ value	8.99809 (rank : 375)	NC score	0.011483 (rank : 411)
Query Neighborhood Hits	406	Target Neighborhood Hits	44	Shared Neighborhood Hits	6
SwissProt Accessions	O14929, Q49A44, Q53QF0, Q53SU4	Gene names	HAT1
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase type B catalytic subunit (EC 2.3.1.48).

HRX_HUMAN
θ value	8.99809 (rank : 376)	NC score	0.032144 (rank : 262)
Query Neighborhood Hits	406	Target Neighborhood Hits	825	Shared Neighborhood Hits	104
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

IF4G1_HUMAN
θ value	8.99809 (rank : 377)	NC score	0.023815 (rank : 309)
Query Neighborhood Hits	406	Target Neighborhood Hits	347	Shared Neighborhood Hits	56
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

K0323_MOUSE
θ value	8.99809 (rank : 378)	NC score	0.011131 (rank : 412)
Query Neighborhood Hits	406	Target Neighborhood Hits	33	Shared Neighborhood Hits	6
SwissProt Accessions	Q80U38, Q8BGJ6, Q8C082	Gene names	Kiaa0323
Domain Architecture	No domain graphic available
Description	Protein KIAA0323.

LATS1_MOUSE
θ value	8.99809 (rank : 379)	NC score	0.002439 (rank : 484)
Query Neighborhood Hits	406	Target Neighborhood Hits	1027	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BYR2, Q9Z0W4	Gene names	Lats1, Warts
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase).

LRC33_MOUSE
θ value	8.99809 (rank : 380)	NC score	0.000945 (rank : 493)
Query Neighborhood Hits	406	Target Neighborhood Hits	296	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BMT4, Q3TIA8, Q8BTT4, Q8BUI7, Q8BY16, Q8R063	Gene names	Lrrc33
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 33 precursor.

LYST_MOUSE
θ value	8.99809 (rank : 381)	NC score	0.006125 (rank : 452)
Query Neighborhood Hits	406	Target Neighborhood Hits	286	Shared Neighborhood Hits	10
SwissProt Accessions	P97412, Q62403, Q8VBS6	Gene names	Lyst, Bg, Chs1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige protein) (CHS1 homolog).

MACF1_MOUSE
θ value	8.99809 (rank : 382)	NC score	0.012394 (rank : 403)
Query Neighborhood Hits	406	Target Neighborhood Hits	1313	Shared Neighborhood Hits	67
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

MAML1_HUMAN
θ value	8.99809 (rank : 383)	NC score	0.012686 (rank : 399)
Query Neighborhood Hits	406	Target Neighborhood Hits	228	Shared Neighborhood Hits	28
SwissProt Accessions	Q92585, Q9NZ12	Gene names	MAML1, KIAA0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

MGR8_HUMAN
θ value	8.99809 (rank : 384)	NC score	0.002110 (rank : 487)
Query Neighborhood Hits	406	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	O00222, O15493, O95945, O95946, Q3MIV9, Q52M02, Q6J165	Gene names	GRM8, GPRC1H, MGLUR8
Domain Architecture
Description	Metabotropic glutamate receptor 8 precursor (mGluR8).

MPIP2_HUMAN
θ value	8.99809 (rank : 385)	NC score	0.004247 (rank : 468)
Query Neighborhood Hits	406	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	P30305, O43551, Q13971, Q5JX77, Q6RSS1, Q9BRA6	Gene names	CDC25B, CDC25HU2
Domain Architecture
Description	M-phase inducer phosphatase 2 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25B).

NCKX1_HUMAN
θ value	8.99809 (rank : 386)	NC score	0.046409 (rank : 214)
Query Neighborhood Hits	406	Target Neighborhood Hits	223	Shared Neighborhood Hits	61
SwissProt Accessions	O60721, O43485, O75184	Gene names	SLC24A1, KIAA0702, NCKX1
Domain Architecture
Description	Sodium/potassium/calcium exchanger 1 (Na(+)/K(+)/Ca(2+)-exchange protein 1) (Retinal rod Na-Ca+K exchanger).

NCOR1_MOUSE
θ value	8.99809 (rank : 387)	NC score	0.041888 (rank : 222)
Query Neighborhood Hits	406	Target Neighborhood Hits	521	Shared Neighborhood Hits	94
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

NEUM_MOUSE
θ value	8.99809 (rank : 388)	NC score	0.056719 (rank : 162)
Query Neighborhood Hits	406	Target Neighborhood Hits	149	Shared Neighborhood Hits	41
SwissProt Accessions	P06837	Gene names	Gap43, Basp2
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (Calmodulin-binding protein P-57).

OGFR_HUMAN
θ value	8.99809 (rank : 389)	NC score	0.029733 (rank : 273)
Query Neighborhood Hits	406	Target Neighborhood Hits	1582	Shared Neighborhood Hits	113
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

PEG3_HUMAN
θ value	8.99809 (rank : 390)	NC score	0.001179 (rank : 491)
Query Neighborhood Hits	406	Target Neighborhood Hits	800	Shared Neighborhood Hits	35
SwissProt Accessions	Q9GZU2, P78418, Q5H9P9, Q7Z7H7, Q8TF75, Q9GZY2	Gene names	PEG3, KIAA0287
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein.

PLVAP_HUMAN
θ value	8.99809 (rank : 391)	NC score	0.012432 (rank : 401)
Query Neighborhood Hits	406	Target Neighborhood Hits	397	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BX97, Q86VP0, Q8N8Y0, Q8ND68, Q8TER8, Q9BZD5	Gene names	PLVAP, FELS, PV1
Domain Architecture	No domain graphic available
Description	Plasmalemma vesicle-associated protein (Plasmalemma vesicle protein 1) (PV-1) (Fenestrated endothelial-linked structure protein).

PORIM_MOUSE
θ value	8.99809 (rank : 392)	NC score	0.017496 (rank : 355)
Query Neighborhood Hits	406	Target Neighborhood Hits	43	Shared Neighborhood Hits	13
SwissProt Accessions	Q91Z22, Q3T9F6, Q3TLL2, Q3U1R6, Q8CEX4	Gene names	Tmem123
Domain Architecture	No domain graphic available
Description	Porimin precursor (Transmembrane protein 123).

PREX1_HUMAN
θ value	8.99809 (rank : 393)	NC score	0.007655 (rank : 440)
Query Neighborhood Hits	406	Target Neighborhood Hits	177	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

RAD18_MOUSE
θ value	8.99809 (rank : 394)	NC score	0.016863 (rank : 361)
Query Neighborhood Hits	406	Target Neighborhood Hits	230	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

RBNS5_HUMAN
θ value	8.99809 (rank : 395)	NC score	0.010139 (rank : 417)
Query Neighborhood Hits	406	Target Neighborhood Hits	242	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H1K0, Q3KP30, Q59EY8, Q8NAQ1	Gene names	ZFYVE20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20) (110 kDa protein).

RHBD3_HUMAN
θ value	8.99809 (rank : 396)	NC score	0.019963 (rank : 327)
Query Neighborhood Hits	406	Target Neighborhood Hits	15	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y3P4, Q6I9X3, Q9UGQ7	Gene names	RHBDD3, C22orf3
Domain Architecture
Description	Rhomboid domain-containing protein 3.

RNPS1_HUMAN
θ value	8.99809 (rank : 397)	NC score	0.017801 (rank : 352)
Query Neighborhood Hits	406	Target Neighborhood Hits	285	Shared Neighborhood Hits	23
SwissProt Accessions	Q15287, O75308, Q8WY42, Q9NYG3	Gene names	RNPS1, LDC2
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2).

RNPS1_MOUSE
θ value	8.99809 (rank : 398)	NC score	0.017801 (rank : 353)
Query Neighborhood Hits	406	Target Neighborhood Hits	285	Shared Neighborhood Hits	23
SwissProt Accessions	Q99M28, Q3TMJ1, Q922H8	Gene names	Rnps1
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1.

SEM6C_HUMAN
θ value	8.99809 (rank : 399)	NC score	0.005210 (rank : 463)
Query Neighborhood Hits	406	Target Neighborhood Hits	117	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H3T2, Q5JR71, Q8WXT8, Q8WXT9, Q8WXU0, Q96JF8	Gene names	SEMA6C, KIAA1869, SEMAY
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

SEPT1_MOUSE
θ value	8.99809 (rank : 400)	NC score	0.002906 (rank : 476)
Query Neighborhood Hits	406	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	P42209	Gene names	Sept1, Diff6, Pnutl3
Domain Architecture
Description	Septin-1 (Differentiation protein 6) (Diff6 protein).

SMRC1_MOUSE
θ value	8.99809 (rank : 401)	NC score	0.024132 (rank : 306)
Query Neighborhood Hits	406	Target Neighborhood Hits	459	Shared Neighborhood Hits	70
SwissProt Accessions	P97496, Q7TS80, Q7TT29	Gene names	Smarcc1, Baf155, Srg3
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155) (SWI3-related protein).

STRN3_HUMAN
θ value	8.99809 (rank : 402)	NC score	0.004093 (rank : 469)
Query Neighborhood Hits	406	Target Neighborhood Hits	316	Shared Neighborhood Hits	12
SwissProt Accessions	Q13033, Q9NRA5	Gene names	STRN3, GS2NA, SG2NA
Domain Architecture
Description	Striatin-3 (Cell-cycle autoantigen SG2NA) (S/G2 antigen).

THUM1_MOUSE
θ value	8.99809 (rank : 403)	NC score	0.018357 (rank : 345)
Query Neighborhood Hits	406	Target Neighborhood Hits	55	Shared Neighborhood Hits	9
SwissProt Accessions	Q99J36, Q3U6Y3	Gene names	Thumpd1
Domain Architecture
Description	THUMP domain-containing protein 1.

TXLNB_HUMAN
θ value	8.99809 (rank : 404)	NC score	0.029557 (rank : 274)
Query Neighborhood Hits	406	Target Neighborhood Hits	912	Shared Neighborhood Hits	84
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

ULE1B_MOUSE
θ value	8.99809 (rank : 405)	NC score	0.008531 (rank : 433)
Query Neighborhood Hits	406	Target Neighborhood Hits	56	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Z1F9, Q8BVX9	Gene names	Uble1b, Sae2, Uba2
Domain Architecture
Description	Ubiquitin-like 1-activating enzyme E1B (SUMO-1-activating enzyme subunit 2) (Anthracycline-associated resistance ARX).

ZN711_HUMAN
θ value	8.99809 (rank : 406)	NC score	-0.000990 (rank : 499)
Query Neighborhood Hits	406	Target Neighborhood Hits	751	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y462, Q6NX42, Q9Y4J6	Gene names	ZNF711, CMPX1, ZNF6
Domain Architecture
Description	Zinc finger protein 711 (Zinc finger protein 6).

ALS2_HUMAN
θ value	θ > 10 (rank : 407)	NC score	0.058135 (rank : 156)
Query Neighborhood Hits	406	Target Neighborhood Hits	121	Shared Neighborhood Hits	12
SwissProt Accessions	Q96Q42, Q8N1E0, Q96PC4, Q96Q41, Q9H973, Q9HCK9	Gene names	ALS2, KIAA1563
Domain Architecture
Description	Alsin (Amyotrophic lateral sclerosis protein 2).

ALS2_MOUSE
θ value	θ > 10 (rank : 408)	NC score	0.056119 (rank : 169)
Query Neighborhood Hits	406	Target Neighborhood Hits	111	Shared Neighborhood Hits	8
SwissProt Accessions	Q920R0, Q8JZR1, Q9CXJ3	Gene names	Als2
Domain Architecture
Description	Alsin (Amyotrophic lateral sclerosis protein 2 homolog).

APBB2_HUMAN
θ value	θ > 10 (rank : 409)	NC score	0.102687 (rank : 62)
Query Neighborhood Hits	406	Target Neighborhood Hits	96	Shared Neighborhood Hits	23
SwissProt Accessions	Q92870, Q8IUI6	Gene names	APBB2, FE65L, FE65L1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2 (Fe65-like protein).

APBB2_MOUSE
θ value	θ > 10 (rank : 410)	NC score	0.099533 (rank : 65)
Query Neighborhood Hits	406	Target Neighborhood Hits	88	Shared Neighborhood Hits	23
SwissProt Accessions	Q9DBR4, Q6DFX8	Gene names	Apbb2
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2.

APBB3_HUMAN
θ value	θ > 10 (rank : 411)	NC score	0.069899 (rank : 112)
Query Neighborhood Hits	406	Target Neighborhood Hits	36	Shared Neighborhood Hits	13
SwissProt Accessions	O95704, Q9NYX6, Q9NYX7, Q9NYX8	Gene names	APBB3, FE65L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 3 (Fe65-like protein 2) (Fe65L2).

APBB3_MOUSE
θ value	θ > 10 (rank : 412)	NC score	0.070247 (rank : 111)
Query Neighborhood Hits	406	Target Neighborhood Hits	32	Shared Neighborhood Hits	13
SwissProt Accessions	Q8R1C9	Gene names	Apbb3
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 3.

APC10_HUMAN
θ value	θ > 10 (rank : 413)	NC score	0.055103 (rank : 173)
Query Neighborhood Hits	406	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UM13, Q2V500, Q9UG51, Q9Y5R0	Gene names	ANAPC10, APC10
Domain Architecture
Description	Anaphase-promoting complex subunit 10 (APC10) (Cyclosome subunit 10).

APC10_MOUSE
θ value	θ > 10 (rank : 414)	NC score	0.052847 (rank : 186)
Query Neighborhood Hits	406	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K2H6, Q9CW24	Gene names	Anapc10, Apc10
Domain Architecture
Description	Anaphase-promoting complex subunit 10 (APC10) (Cyclosome subunit 10).

BAG3_HUMAN
θ value	θ > 10 (rank : 415)	NC score	0.223765 (rank : 40)
Query Neighborhood Hits	406	Target Neighborhood Hits	314	Shared Neighborhood Hits	50
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

BAG3_MOUSE
θ value	θ > 10 (rank : 416)	NC score	0.194432 (rank : 45)
Query Neighborhood Hits	406	Target Neighborhood Hits	513	Shared Neighborhood Hits	67
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

BASP_HUMAN
θ value	θ > 10 (rank : 417)	NC score	0.062690 (rank : 140)
Query Neighborhood Hits	406	Target Neighborhood Hits	321	Shared Neighborhood Hits	61
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BASP_MOUSE
θ value	θ > 10 (rank : 418)	NC score	0.061192 (rank : 145)
Query Neighborhood Hits	406	Target Neighborhood Hits	260	Shared Neighborhood Hits	47
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

CUL7_HUMAN
θ value	θ > 10 (rank : 419)	NC score	0.067632 (rank : 118)
Query Neighborhood Hits	406	Target Neighborhood Hits	41	Shared Neighborhood Hits	5
SwissProt Accessions	Q14999, Q5T654	Gene names	CUL7, KIAA0076
Domain Architecture
Description	Cullin-7 (CUL-7).

DOC2A_HUMAN
θ value	θ > 10 (rank : 420)	NC score	0.056489 (rank : 168)
Query Neighborhood Hits	406	Target Neighborhood Hits	144	Shared Neighborhood Hits	14
SwissProt Accessions	Q14183, Q6P4G4, Q7Z5G0, Q8IVX0	Gene names	DOC2A
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha) (Doc2).

DOC2A_MOUSE
θ value	θ > 10 (rank : 421)	NC score	0.059147 (rank : 150)
Query Neighborhood Hits	406	Target Neighborhood Hits	140	Shared Neighborhood Hits	12
SwissProt Accessions	Q7TNF0	Gene names	Doc2a
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha).

DOC2B_HUMAN
θ value	θ > 10 (rank : 422)	NC score	0.054807 (rank : 176)
Query Neighborhood Hits	406	Target Neighborhood Hits	150	Shared Neighborhood Hits	14
SwissProt Accessions	Q14184	Gene names	DOC2B
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

DOC2B_MOUSE
θ value	θ > 10 (rank : 423)	NC score	0.054395 (rank : 179)
Query Neighborhood Hits	406	Target Neighborhood Hits	169	Shared Neighborhood Hits	16
SwissProt Accessions	P70169, Q6NXK3	Gene names	Doc2b
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

DRP2_HUMAN
θ value	θ > 10 (rank : 424)	NC score	0.056699 (rank : 164)
Query Neighborhood Hits	406	Target Neighborhood Hits	186	Shared Neighborhood Hits	27
SwissProt Accessions	Q13474	Gene names	DRP2
Domain Architecture
Description	Dystrophin-related protein 2.

DSPP_MOUSE
θ value	θ > 10 (rank : 425)	NC score	0.063063 (rank : 138)
Query Neighborhood Hits	406	Target Neighborhood Hits	491	Shared Neighborhood Hits	90
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

FA62A_HUMAN
θ value	θ > 10 (rank : 426)	NC score	0.068011 (rank : 117)
Query Neighborhood Hits	406	Target Neighborhood Hits	168	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BSJ8, O94848, Q6PJN4, Q9H6J1, Q9H6W2, Q9Y416	Gene names	FAM62A, KIAA0747, MBC2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

FA62A_MOUSE
θ value	θ > 10 (rank : 427)	NC score	0.078850 (rank : 97)
Query Neighborhood Hits	406	Target Neighborhood Hits	155	Shared Neighborhood Hits	16
SwissProt Accessions	Q3U7R1, Q8C8R1, Q91X62, Q9CVH0, Q9Z1X5, Q9Z1X6	Gene names	Fam62a, Mbc2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

GAS7_HUMAN
θ value	θ > 10 (rank : 428)	NC score	0.142755 (rank : 54)
Query Neighborhood Hits	406	Target Neighborhood Hits	258	Shared Neighborhood Hits	28
SwissProt Accessions	O60861, O43144	Gene names	GAS7, KIAA0394
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

GAS7_MOUSE
θ value	θ > 10 (rank : 429)	NC score	0.140428 (rank : 55)
Query Neighborhood Hits	406	Target Neighborhood Hits	259	Shared Neighborhood Hits	27
SwissProt Accessions	Q60780, Q9QY25, Q9QY26, Q9QY34	Gene names	Gas7
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

K1333_MOUSE
θ value	θ > 10 (rank : 430)	NC score	0.065846 (rank : 128)
Query Neighborhood Hits	406	Target Neighborhood Hits	53	Shared Neighborhood Hits	16
SwissProt Accessions	Q5RJY2, Q6ZPT7, Q8BNA4	Gene names	Kiaa1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

MAGI1_HUMAN
θ value	θ > 10 (rank : 431)	NC score	0.149824 (rank : 53)
Query Neighborhood Hits	406	Target Neighborhood Hits	388	Shared Neighborhood Hits	39
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

MAGI1_MOUSE
θ value	θ > 10 (rank : 432)	NC score	0.150989 (rank : 52)
Query Neighborhood Hits	406	Target Neighborhood Hits	403	Shared Neighborhood Hits	40
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

MAGI2_HUMAN
θ value	θ > 10 (rank : 433)	NC score	0.153519 (rank : 51)
Query Neighborhood Hits	406	Target Neighborhood Hits	373	Shared Neighborhood Hits	44
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

MAGI2_MOUSE
θ value	θ > 10 (rank : 434)	NC score	0.161880 (rank : 50)
Query Neighborhood Hits	406	Target Neighborhood Hits	370	Shared Neighborhood Hits	42
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

MAP1B_HUMAN
θ value	θ > 10 (rank : 435)	NC score	0.051648 (rank : 194)
Query Neighborhood Hits	406	Target Neighborhood Hits	903	Shared Neighborhood Hits	116
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

MAP1B_MOUSE
θ value	θ > 10 (rank : 436)	NC score	0.054260 (rank : 181)
Query Neighborhood Hits	406	Target Neighborhood Hits	977	Shared Neighborhood Hits	126
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

MYCB2_HUMAN
θ value	θ > 10 (rank : 437)	NC score	0.058137 (rank : 155)
Query Neighborhood Hits	406	Target Neighborhood Hits	390	Shared Neighborhood Hits	42
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

MYCB2_MOUSE
θ value	θ > 10 (rank : 438)	NC score	0.054829 (rank : 175)
Query Neighborhood Hits	406	Target Neighborhood Hits	307	Shared Neighborhood Hits	36
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

NOLC1_HUMAN
θ value	θ > 10 (rank : 439)	NC score	0.059025 (rank : 152)
Query Neighborhood Hits	406	Target Neighborhood Hits	452	Shared Neighborhood Hits	75
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

NSBP1_HUMAN
θ value	θ > 10 (rank : 440)	NC score	0.070847 (rank : 110)
Query Neighborhood Hits	406	Target Neighborhood Hits	251	Shared Neighborhood Hits	58
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

PA24B_MOUSE
θ value	θ > 10 (rank : 441)	NC score	0.054026 (rank : 182)
Query Neighborhood Hits	406	Target Neighborhood Hits	102	Shared Neighborhood Hits	11
SwissProt Accessions	Q4QQM1, Q80VV8, Q91W88	Gene names	Pla2g4b
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

PARC_HUMAN
θ value	θ > 10 (rank : 442)	NC score	0.050898 (rank : 199)
Query Neighborhood Hits	406	Target Neighborhood Hits	148	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IWT3, O75188, Q68CP2, Q68D92, Q8N3W9, Q9BU56	Gene names	PARC, H7AP1, KIAA0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein (UbcH7-associated protein 1).

PARC_MOUSE
θ value	θ > 10 (rank : 443)	NC score	0.055054 (rank : 174)
Query Neighborhood Hits	406	Target Neighborhood Hits	114	Shared Neighborhood Hits	17
SwissProt Accessions	Q80TT8, Q8BKL9, Q8CGC0, Q8R363	Gene names	Parc, Kiaa0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein.

PELP1_HUMAN
θ value	θ > 10 (rank : 444)	NC score	0.056491 (rank : 167)
Query Neighborhood Hits	406	Target Neighborhood Hits	596	Shared Neighborhood Hits	96
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

PIN1_HUMAN
θ value	θ > 10 (rank : 445)	NC score	0.221015 (rank : 41)
Query Neighborhood Hits	406	Target Neighborhood Hits	59	Shared Neighborhood Hits	13
SwissProt Accessions	Q13526	Gene names	PIN1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

PIN1_MOUSE
θ value	θ > 10 (rank : 446)	NC score	0.220271 (rank : 42)
Query Neighborhood Hits	406	Target Neighborhood Hits	60	Shared Neighborhood Hits	15
SwissProt Accessions	Q9QUR7, Q543B3	Gene names	Pin1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

PINL_HUMAN
θ value	θ > 10 (rank : 447)	NC score	0.263159 (rank : 37)
Query Neighborhood Hits	406	Target Neighborhood Hits	47	Shared Neighborhood Hits	15
SwissProt Accessions	O15428	Gene names	PIN1L
Domain Architecture
Description	PIN1-like protein.

PKHA5_HUMAN
θ value	θ > 10 (rank : 448)	NC score	0.166371 (rank : 49)
Query Neighborhood Hits	406	Target Neighborhood Hits	455	Shared Neighborhood Hits	49
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

PRG4_MOUSE
θ value	θ > 10 (rank : 449)	NC score	0.055751 (rank : 171)
Query Neighborhood Hits	406	Target Neighborhood Hits	624	Shared Neighborhood Hits	88
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRP40_HUMAN
θ value	θ > 10 (rank : 450)	NC score	0.132588 (rank : 57)
Query Neighborhood Hits	406	Target Neighborhood Hits	442	Shared Neighborhood Hits	54
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

PRP40_MOUSE
θ value	θ > 10 (rank : 451)	NC score	0.132880 (rank : 56)
Query Neighborhood Hits	406	Target Neighborhood Hits	447	Shared Neighborhood Hits	57
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

PTMA_HUMAN
θ value	θ > 10 (rank : 452)	NC score	0.078462 (rank : 98)
Query Neighborhood Hits	406	Target Neighborhood Hits	88	Shared Neighborhood Hits	40
SwissProt Accessions	P06454, Q15249, Q15592	Gene names	PTMA, TMSA
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha-1].

PTMA_MOUSE
θ value	θ > 10 (rank : 453)	NC score	0.076181 (rank : 101)
Query Neighborhood Hits	406	Target Neighborhood Hits	73	Shared Neighborhood Hits	34
SwissProt Accessions	P26350, Q3UQV6	Gene names	Ptma
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha].

PTMS_HUMAN
θ value	θ > 10 (rank : 454)	NC score	0.050971 (rank : 198)
Query Neighborhood Hits	406	Target Neighborhood Hits	111	Shared Neighborhood Hits	32
SwissProt Accessions	P20962	Gene names	PTMS
Domain Architecture	No domain graphic available
Description	Parathymosin.

PTMS_MOUSE
θ value	θ > 10 (rank : 455)	NC score	0.056946 (rank : 160)
Query Neighborhood Hits	406	Target Neighborhood Hits	68	Shared Neighborhood Hits	25
SwissProt Accessions	Q9D0J8	Gene names	Ptms
Domain Architecture	No domain graphic available
Description	Parathymosin.

RASL1_HUMAN
θ value	θ > 10 (rank : 456)	NC score	0.064479 (rank : 133)
Query Neighborhood Hits	406	Target Neighborhood Hits	142	Shared Neighborhood Hits	11
SwissProt Accessions	O95294, Q52M03, Q96CC7	Gene names	RASAL1, RASAL
Domain Architecture
Description	RasGAP-activating-like protein 1.

RASL1_MOUSE
θ value	θ > 10 (rank : 457)	NC score	0.060851 (rank : 146)
Query Neighborhood Hits	406	Target Neighborhood Hits	148	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z268	Gene names	Rasal1, Rasal
Domain Architecture
Description	RasGAP-activating-like protein 1.

RASL2_HUMAN
θ value	θ > 10 (rank : 458)	NC score	0.057913 (rank : 158)
Query Neighborhood Hits	406	Target Neighborhood Hits	161	Shared Neighborhood Hits	11
SwissProt Accessions	O43374, O60286, Q86UW3, Q96QU0	Gene names	RASA4, CAPRI, GAPL, KIAA0538
Domain Architecture
Description	Ras GTPase-activating protein 4 (RasGAP-activating-like protein 2) (Calcium-promoted Ras inactivator).

RCBT1_HUMAN
θ value	θ > 10 (rank : 459)	NC score	0.065635 (rank : 130)
Query Neighborhood Hits	406	Target Neighborhood Hits	158	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NDN9, Q969U9	Gene names	RCBTB1, CLLD7, E4.5
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 1 (Regulator of chromosome condensation and BTB domain-containing protein 1) (Chronic lymphocytic leukemia deletion region gene 7 protein) (CLL deletion region gene 7 protein).

RCBT1_MOUSE
θ value	θ > 10 (rank : 460)	NC score	0.067354 (rank : 121)
Query Neighborhood Hits	406	Target Neighborhood Hits	157	Shared Neighborhood Hits	9
SwissProt Accessions	Q6NXM2, Q8BTZ6, Q8BZV0	Gene names	Rcbtb1
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 1 (Regulator of chromosome condensation and BTB domain-containing protein 1).

RCBT2_HUMAN
θ value	θ > 10 (rank : 461)	NC score	0.073010 (rank : 107)
Query Neighborhood Hits	406	Target Neighborhood Hits	158	Shared Neighborhood Hits	10
SwissProt Accessions	O95199	Gene names	RCBTB2, CHC1L, RLG
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 2 (Regulator of chromosome condensation and BTB domain-containing protein 2) (Chromosome condensation 1-like) (CHC1-L) (RCC1-like G exchanging factor).

RCBT2_MOUSE
θ value	θ > 10 (rank : 462)	NC score	0.074188 (rank : 104)
Query Neighborhood Hits	406	Target Neighborhood Hits	156	Shared Neighborhood Hits	11
SwissProt Accessions	Q99LJ7, Q3TUA3, Q8BMG2	Gene names	Rcbtb2, Chc1l
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 2 (Regulator of chromosome condensation and BTB domain-containing protein 2) (Chromosome condensation 1-like).

RCC1_HUMAN
θ value	θ > 10 (rank : 463)	NC score	0.088867 (rank : 78)
Query Neighborhood Hits	406	Target Neighborhood Hits	47	Shared Neighborhood Hits	6
SwissProt Accessions	P18754	Gene names	RCC1, CHC1
Domain Architecture
Description	Regulator of chromosome condensation (Chromosome condensation protein 1) (Cell cycle regulatory protein).

RCC1_MOUSE
θ value	θ > 10 (rank : 464)	NC score	0.086730 (rank : 80)
Query Neighborhood Hits	406	Target Neighborhood Hits	45	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VE37, Q3UDB6	Gene names	Rcc1, Chc1
Domain Architecture	No domain graphic available
Description	Regulator of chromosome condensation (Chromosome condensation protein 1).

RCC2_HUMAN
θ value	θ > 10 (rank : 465)	NC score	0.091363 (rank : 72)
Query Neighborhood Hits	406	Target Neighborhood Hits	36	Shared Neighborhood Hits	8
SwissProt Accessions	Q9P258, Q8IVL9, Q9BSN6, Q9NPV8	Gene names	RCC2, KIAA1470, TD60
Domain Architecture	No domain graphic available
Description	Protein RCC2 (Telophase disk protein of 60 kDa) (RCC1-like protein TD- 60).

RCC2_MOUSE
θ value	θ > 10 (rank : 466)	NC score	0.090704 (rank : 74)
Query Neighborhood Hits	406	Target Neighborhood Hits	37	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BK67, Q6ZPQ0	Gene names	Rcc2, Kiaa1470
Domain Architecture	No domain graphic available
Description	Protein RCC2.

RHG12_HUMAN
θ value	θ > 10 (rank : 467)	NC score	0.059880 (rank : 148)
Query Neighborhood Hits	406	Target Neighborhood Hits	190	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RHG12_MOUSE
θ value	θ > 10 (rank : 468)	NC score	0.068491 (rank : 114)
Query Neighborhood Hits	406	Target Neighborhood Hits	204	Shared Neighborhood Hits	19
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RIMS2_HUMAN
θ value	θ > 10 (rank : 469)	NC score	0.053608 (rank : 183)
Query Neighborhood Hits	406	Target Neighborhood Hits	342	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

RIMS2_MOUSE
θ value	θ > 10 (rank : 470)	NC score	0.052050 (rank : 192)
Query Neighborhood Hits	406	Target Neighborhood Hits	376	Shared Neighborhood Hits	37
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

RP1L1_HUMAN
θ value	θ > 10 (rank : 471)	NC score	0.052564 (rank : 187)
Query Neighborhood Hits	406	Target Neighborhood Hits	1072	Shared Neighborhood Hits	142
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

RPGR_MOUSE
θ value	θ > 10 (rank : 472)	NC score	0.100003 (rank : 64)
Query Neighborhood Hits	406	Target Neighborhood Hits	281	Shared Neighborhood Hits	39
SwissProt Accessions	Q9R0X5, O88408, Q9CU92	Gene names	Rpgr
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator (mRpgr).

SAV1_HUMAN
θ value	θ > 10 (rank : 473)	NC score	0.281895 (rank : 36)
Query Neighborhood Hits	406	Target Neighborhood Hits	51	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H4B6, Q6IA58, Q9H949, Q9HAK9	Gene names	SAV1, WW45
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (hWW45).

SAV1_MOUSE
θ value	θ > 10 (rank : 474)	NC score	0.281955 (rank : 35)
Query Neighborhood Hits	406	Target Neighborhood Hits	48	Shared Neighborhood Hits	14
SwissProt Accessions	Q8VEB2, Q9D9N9, Q9ER46	Gene names	Sav1, Ww45, Wwp3
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (mWW45).

SETD2_HUMAN
θ value	θ > 10 (rank : 475)	NC score	0.090212 (rank : 75)
Query Neighborhood Hits	406	Target Neighborhood Hits	412	Shared Neighborhood Hits	65
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SRGEF_HUMAN
θ value	θ > 10 (rank : 476)	NC score	0.095956 (rank : 67)
Query Neighborhood Hits	406	Target Neighborhood Hits	33	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UGK8, Q9UGK9	Gene names	SERGEF, DELGEF, GNEFR
Domain Architecture	No domain graphic available
Description	Secretion-regulating guanine nucleotide exchange factor (Guanine nucleotide exchange factor-related protein) (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF).

SRGEF_MOUSE
θ value	θ > 10 (rank : 477)	NC score	0.092791 (rank : 70)
Query Neighborhood Hits	406	Target Neighborhood Hits	37	Shared Neighborhood Hits	8
SwissProt Accessions	Q80YD6, Q9QXB7	Gene names	Sergef, Delgef, Gnefr
Domain Architecture	No domain graphic available
Description	Secretion-regulating guanine nucleotide exchange factor (Guanine nucleotide exchange factor-related protein) (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF).

SRRM2_HUMAN
θ value	θ > 10 (rank : 478)	NC score	0.058719 (rank : 153)
Query Neighborhood Hits	406	Target Neighborhood Hits	1296	Shared Neighborhood Hits	148
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SRRM2_MOUSE
θ value	θ > 10 (rank : 479)	NC score	0.055959 (rank : 170)
Query Neighborhood Hits	406	Target Neighborhood Hits	1470	Shared Neighborhood Hits	148
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

STXB4_HUMAN
θ value	θ > 10 (rank : 480)	NC score	0.091753 (rank : 71)
Query Neighborhood Hits	406	Target Neighborhood Hits	616	Shared Neighborhood Hits	41
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

STXB4_MOUSE
θ value	θ > 10 (rank : 481)	NC score	0.090965 (rank : 73)
Query Neighborhood Hits	406	Target Neighborhood Hits	629	Shared Neighborhood Hits	43
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

T2FA_HUMAN
θ value	θ > 10 (rank : 482)	NC score	0.053280 (rank : 184)
Query Neighborhood Hits	406	Target Neighborhood Hits	228	Shared Neighborhood Hits	59
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

TCOF_MOUSE
θ value	θ > 10 (rank : 483)	NC score	0.060335 (rank : 147)
Query Neighborhood Hits	406	Target Neighborhood Hits	471	Shared Neighborhood Hits	78
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

TCRG1_HUMAN
θ value	θ > 10 (rank : 484)	NC score	0.058407 (rank : 154)
Query Neighborhood Hits	406	Target Neighborhood Hits	929	Shared Neighborhood Hits	85
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TCRG1_MOUSE
θ value	θ > 10 (rank : 485)	NC score	0.059284 (rank : 149)
Query Neighborhood Hits	406	Target Neighborhood Hits	947	Shared Neighborhood Hits	97
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

TOLIP_HUMAN
θ value	θ > 10 (rank : 486)	NC score	0.054366 (rank : 180)
Query Neighborhood Hits	406	Target Neighborhood Hits	20	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H0E2, Q9H9E6, Q9UJ69	Gene names	TOLLIP
Domain Architecture
Description	Toll-interacting protein.

TOLIP_MOUSE
θ value	θ > 10 (rank : 487)	NC score	0.056729 (rank : 161)
Query Neighborhood Hits	406	Target Neighborhood Hits	24	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QZ06, Q543N1, Q9D5P5	Gene names	Tollip
Domain Architecture
Description	Toll-interacting protein.

UN13A_HUMAN
θ value	θ > 10 (rank : 488)	NC score	0.083349 (rank : 89)
Query Neighborhood Hits	406	Target Neighborhood Hits	285	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

UN13B_HUMAN
θ value	θ > 10 (rank : 489)	NC score	0.074652 (rank : 102)
Query Neighborhood Hits	406	Target Neighborhood Hits	217	Shared Neighborhood Hits	16
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

UN13B_MOUSE
θ value	θ > 10 (rank : 490)	NC score	0.074472 (rank : 103)
Query Neighborhood Hits	406	Target Neighborhood Hits	210	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

UN13D_HUMAN
θ value	θ > 10 (rank : 491)	NC score	0.051345 (rank : 195)
Query Neighborhood Hits	406	Target Neighborhood Hits	117	Shared Neighborhood Hits	8
SwissProt Accessions	Q70J99, Q9H7K5	Gene names	UNC13D
Domain Architecture	No domain graphic available
Description	Unc-13 homolog D (Munc13-4).

VCX1_HUMAN
θ value	θ > 10 (rank : 492)	NC score	0.055322 (rank : 172)
Query Neighborhood Hits	406	Target Neighborhood Hits	129	Shared Neighborhood Hits	37
SwissProt Accessions	Q9H320, Q9P0H3	Gene names	VCX, VCX1, VCX10R, VCXB1
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 1 (VCX-B1 protein) (Variably charged protein X-B1) (Variable charge protein on X with ten repeats) (VCX- 10r).

VCX3_HUMAN
θ value	θ > 10 (rank : 493)	NC score	0.062607 (rank : 141)
Query Neighborhood Hits	406	Target Neighborhood Hits	105	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NNX9, Q9P0H4	Gene names	VCX3A, VCX3, VCX8R, VCXA
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 3 (VCX-A protein) (Variably charged protein X-A) (Variable charge protein on X with eight repeats) (VCX- 8r).

VCXC_HUMAN
θ value	θ > 10 (rank : 494)	NC score	0.061788 (rank : 143)
Query Neighborhood Hits	406	Target Neighborhood Hits	139	Shared Neighborhood Hits	41
SwissProt Accessions	Q9H321	Gene names	VCXC
Domain Architecture	No domain graphic available
Description	VCX-C protein (Variably charged protein X-C).

WBP4_MOUSE
θ value	θ > 10 (rank : 495)	NC score	0.066293 (rank : 125)
Query Neighborhood Hits	406	Target Neighborhood Hits	100	Shared Neighborhood Hits	24
SwissProt Accessions	Q61048, Q8K1Z9, Q9CS45	Gene names	Wbp4, Fbp21, Fnbp21
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 4 (WBP-4) (Formin-binding protein 21).

WBS16_HUMAN
θ value	θ > 10 (rank : 496)	NC score	0.083144 (rank : 91)
Query Neighborhood Hits	406	Target Neighborhood Hits	29	Shared Neighborhood Hits	6
SwissProt Accessions	Q96I51, Q548B1, Q9H0G7	Gene names	WBSCR16
Domain Architecture	No domain graphic available
Description	Williams-Beuren syndrome chromosome region 16 protein (RCC1-like G exchanging factor-like protein).

WBS16_MOUSE
θ value	θ > 10 (rank : 497)	NC score	0.084711 (rank : 84)
Query Neighborhood Hits	406	Target Neighborhood Hits	31	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CYF5	Gene names	Wbscr16
Domain Architecture	No domain graphic available
Description	Williams-Beuren syndrome chromosome region 16 protein homolog.

WWC1_HUMAN
θ value	θ > 10 (rank : 498)	NC score	0.239980 (rank : 38)
Query Neighborhood Hits	406	Target Neighborhood Hits	290	Shared Neighborhood Hits	37
SwissProt Accessions	Q8IX03, O94946, Q6MZX4, Q6Y2F8, Q7Z4G8, Q8WVM4, Q9BT29	Gene names	WWC1, KIAA0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA) (HBeAg-binding protein 3).

WWC1_MOUSE
θ value	θ > 10 (rank : 499)	NC score	0.239427 (rank : 39)
Query Neighborhood Hits	406	Target Neighborhood Hits	290	Shared Neighborhood Hits	31
SwissProt Accessions	Q5SXA9, Q571D0, Q8K1Y3, Q8VD17, Q922W3	Gene names	Wwc1, Kiaa0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA).

WWOX_HUMAN
θ value	θ > 10 (rank : 500)	NC score	0.218677 (rank : 43)
Query Neighborhood Hits	406	Target Neighborhood Hits	115	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NZC7, Q5MYT5, Q96KM3, Q96RF2, Q9BTT8, Q9NPC9, Q9NRF4, Q9NRF5, Q9NRF6, Q9NRK1, Q9NZC5	Gene names	WWOX, FOR, WOX1
Domain Architecture	No domain graphic available
Description	WW domain-containing oxidoreductase (EC 1.1.1.-) (Fragile site FRA16D oxidoreductase).

WWOX_MOUSE
θ value	θ > 10 (rank : 501)	NC score	0.216763 (rank : 44)
Query Neighborhood Hits	406	Target Neighborhood Hits	118	Shared Neighborhood Hits	14
SwissProt Accessions	Q91WL8, Q8C8J6, Q920Y2, Q9D2B3, Q9D339, Q9JLF5	Gene names	Wwox, Wox1
Domain Architecture	No domain graphic available
Description	WW domain-containing oxidoreductase (EC 1.1.1.-).

WWTR1_HUMAN
θ value	θ > 10 (rank : 502)	NC score	0.189056 (rank : 47)
Query Neighborhood Hits	406	Target Neighborhood Hits	76	Shared Neighborhood Hits	18
SwissProt Accessions	Q9GZV5, Q8N3P2, Q9Y3W6	Gene names	WWTR1, TAZ
Domain Architecture	No domain graphic available
Description	WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif).

WWTR1_MOUSE
θ value	θ > 10 (rank : 503)	NC score	0.191372 (rank : 46)
Query Neighborhood Hits	406	Target Neighborhood Hits	54	Shared Neighborhood Hits	14
SwissProt Accessions	Q9EPK5, Q99KI4	Gene names	Wwtr1, Taz
Domain Architecture	No domain graphic available
Description	WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif).

YAP1_HUMAN
θ value	θ > 10 (rank : 504)	NC score	0.185362 (rank : 48)
Query Neighborhood Hits	406	Target Neighborhood Hits	173	Shared Neighborhood Hits	34
SwissProt Accessions	P46937	Gene names	YAP1, YAP65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

YAP1_MOUSE
θ value	θ > 10 (rank : 505)	NC score	0.313470 (rank : 34)
Query Neighborhood Hits	406	Target Neighborhood Hits	96	Shared Neighborhood Hits	25
SwissProt Accessions	P46938, Q52KJ5	Gene names	Yap1, Yap, Yap65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

Hits sorted by NC score

HUWE1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	406	Target Neighborhood Hits	406	Shared Neighborhood Hits	406
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

HUWE1_HUMAN
NC score	0.989016 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	406	Target Neighborhood Hits	443	Shared Neighborhood Hits	300
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

SMUF1_HUMAN
NC score	0.882187 (rank : 3)	θ value	2.46618e-90 (rank : 11)
Query Neighborhood Hits	406	Target Neighborhood Hits	135	Shared Neighborhood Hits	38
SwissProt Accessions	Q9HCE7, O75853, Q9UJT8	Gene names	SMURF1, KIAA1625
Domain Architecture
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) (hSMURF1).

SMUF1_MOUSE
NC score	0.879241 (rank : 4)	θ value	4.96919e-91 (rank : 9)
Query Neighborhood Hits	406	Target Neighborhood Hits	142	Shared Neighborhood Hits	39
SwissProt Accessions	Q9CUN6, Q3U412, Q8K300	Gene names	Smurf1
Domain Architecture	No domain graphic available
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1).

HECD2_MOUSE
NC score	0.878313 (rank : 5)	θ value	7.75577e-52 (rank : 20)
Query Neighborhood Hits	406	Target Neighborhood Hits	38	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CDU6, Q8CBQ9	Gene names	Hectd2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

K0317_HUMAN
NC score	0.878215 (rank : 6)	θ value	2.41096e-53 (rank : 17)
Query Neighborhood Hits	406	Target Neighborhood Hits	46	Shared Neighborhood Hits	33
SwissProt Accessions	O15033, Q7LDY1, Q8IYY9	Gene names	KIAA0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

K0317_MOUSE
NC score	0.878197 (rank : 7)	θ value	1.84601e-53 (rank : 16)
Query Neighborhood Hits	406	Target Neighborhood Hits	43	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CHG5, Q6P9Q1, Q80YC4, Q8C5W5	Gene names	Kiaa0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

SMUF2_HUMAN
NC score	0.878175 (rank : 8)	θ value	4.96919e-91 (rank : 10)
Query Neighborhood Hits	406	Target Neighborhood Hits	142	Shared Neighborhood Hits	38
SwissProt Accessions	Q9HAU4, Q9H260	Gene names	SMURF2
Domain Architecture
Description	Smad ubiquitination regulatory factor 2 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF2) (Smad-specific E3 ubiquitin ligase 2) (hSMURF2).

HECD2_HUMAN
NC score	0.876076 (rank : 9)	θ value	7.75577e-52 (rank : 19)
Query Neighborhood Hits	406	Target Neighborhood Hits	41	Shared Neighborhood Hits	33
SwissProt Accessions	Q5U5R9, Q5VZ97, Q5VZ99, Q8TCP5	Gene names	HECTD2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

ITCH_MOUSE
NC score	0.875344 (rank : 10)	θ value	5.30912e-93 (rank : 6)
Query Neighborhood Hits	406	Target Neighborhood Hits	127	Shared Neighborhood Hits	37
SwissProt Accessions	Q8C863, O54971	Gene names	Itch
Domain Architecture
Description	Itchy E3 ubiquitin protein ligase (EC 6.3.2.-).

UBE3A_HUMAN
NC score	0.874774 (rank : 11)	θ value	2.66562e-52 (rank : 18)
Query Neighborhood Hits	406	Target Neighborhood Hits	49	Shared Neighborhood Hits	34
SwissProt Accessions	Q05086, P78355, Q93066, Q9UEP4, Q9UEP5, Q9UEP6, Q9UEP7, Q9UEP8, Q9UEP9	Gene names	UBE3A, E6AP
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (E6AP ubiquitin-protein ligase) (Oncogenic protein-associated protein E6-AP) (Human papillomavirus E6-associated protein) (NY-REN-54 antigen).

WWP2_MOUSE
NC score	0.869926 (rank : 12)	θ value	1.14559e-87 (rank : 15)
Query Neighborhood Hits	406	Target Neighborhood Hits	118	Shared Neighborhood Hits	47
SwissProt Accessions	Q9DBH0, Q8BTG4, Q923F6	Gene names	Wwp2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2).

UBE3A_MOUSE
NC score	0.869827 (rank : 13)	θ value	6.14528e-49 (rank : 21)
Query Neighborhood Hits	406	Target Neighborhood Hits	47	Shared Neighborhood Hits	35
SwissProt Accessions	O08759, P97482	Gene names	Ube3a
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (Oncogenic protein- associated protein E6-AP).

WWP2_HUMAN
NC score	0.868745 (rank : 14)	θ value	1.14559e-87 (rank : 14)
Query Neighborhood Hits	406	Target Neighborhood Hits	177	Shared Neighborhood Hits	51
SwissProt Accessions	O00308, Q96CZ2, Q9BWN6	Gene names	WWP2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2) (Atrophin-1-interacting protein 2) (AIP2).

ITCH_HUMAN
NC score	0.868130 (rank : 15)	θ value	3.44127e-92 (rank : 8)
Query Neighborhood Hits	406	Target Neighborhood Hits	162	Shared Neighborhood Hits	44
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

WWP1_MOUSE
NC score	0.867673 (rank : 16)	θ value	7.93343e-89 (rank : 13)
Query Neighborhood Hits	406	Target Neighborhood Hits	138	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BZZ3, Q8BIV9, Q8VDP8	Gene names	Wwp1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1).

WWP1_HUMAN
NC score	0.864459 (rank : 17)	θ value	7.93343e-89 (rank : 12)
Query Neighborhood Hits	406	Target Neighborhood Hits	262	Shared Neighborhood Hits	72
SwissProt Accessions	Q9H0M0, O00307, Q96BP4	Gene names	WWP1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1) (Atropin-1-interacting protein 5) (AIP5).

UBE3C_HUMAN
NC score	0.863909 (rank : 18)	θ value	1.51363e-47 (rank : 22)
Query Neighborhood Hits	406	Target Neighborhood Hits	51	Shared Neighborhood Hits	33
SwissProt Accessions	Q15386, Q8TC15, Q96CR4, Q9UDU3	Gene names	UBE3C, KIAA0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

UBE3C_MOUSE
NC score	0.862572 (rank : 19)	θ value	9.81109e-47 (rank : 23)
Query Neighborhood Hits	406	Target Neighborhood Hits	48	Shared Neighborhood Hits	33
SwissProt Accessions	Q80U95, Q8BQZ6, Q8C7W6, Q8CDJ1, Q8VDL5	Gene names	Ube3c, Kiaa0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

NEDD4_MOUSE
NC score	0.830925 (rank : 20)	θ value	2.63489e-92 (rank : 7)
Query Neighborhood Hits	406	Target Neighborhood Hits	212	Shared Neighborhood Hits	42
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

NEDD4_HUMAN
NC score	0.824997 (rank : 21)	θ value	4.06505e-93 (rank : 5)
Query Neighborhood Hits	406	Target Neighborhood Hits	214	Shared Neighborhood Hits	40
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).

NED4L_MOUSE
NC score	0.811742 (rank : 22)	θ value	2.81514e-94 (rank : 4)
Query Neighborhood Hits	406	Target Neighborhood Hits	231	Shared Neighborhood Hits	42
SwissProt Accessions	Q8CFI0, Q8BRT9, Q8BS42, Q99PK2	Gene names	Nedd4l, Kiaa0439, Nedd4b
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

NED4L_HUMAN
NC score	0.810475 (rank : 23)	θ value	2.81514e-94 (rank : 3)
Query Neighborhood Hits	406	Target Neighborhood Hits	238	Shared Neighborhood Hits	43
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

TRIPC_HUMAN
NC score	0.794235 (rank : 24)	θ value	4.14116e-29 (rank : 27)
Query Neighborhood Hits	406	Target Neighborhood Hits	319	Shared Neighborhood Hits	61
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

HECD3_MOUSE
NC score	0.729253 (rank : 25)	θ value	4.73814e-25 (rank : 31)
Query Neighborhood Hits	406	Target Neighborhood Hits	47	Shared Neighborhood Hits	33
SwissProt Accessions	Q3U487, Q3TN76, Q641P3, Q8BQ74, Q8R1L6	Gene names	Hectd3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

HECD3_HUMAN
NC score	0.725264 (rank : 26)	θ value	1.37858e-24 (rank : 32)
Query Neighborhood Hits	406	Target Neighborhood Hits	49	Shared Neighborhood Hits	33
SwissProt Accessions	Q5T447, Q5T448, Q9H783	Gene names	HECTD3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

HERC3_HUMAN
NC score	0.723631 (rank : 27)	θ value	5.21438e-40 (rank : 24)
Query Neighborhood Hits	406	Target Neighborhood Hits	62	Shared Neighborhood Hits	35
SwissProt Accessions	Q15034	Gene names	HERC3, KIAA0032
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain protein 3.

HERC5_HUMAN
NC score	0.720104 (rank : 28)	θ value	3.87602e-27 (rank : 28)
Query Neighborhood Hits	406	Target Neighborhood Hits	66	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UII4	Gene names	HERC5, CEB1, CEBP1
Domain Architecture
Description	HECT domain and RCC1-like domain-containing protein 5 (Cyclin-E- binding protein 1).

EDD1_MOUSE
NC score	0.700234 (rank : 29)	θ value	1.62847e-25 (rank : 30)
Query Neighborhood Hits	406	Target Neighborhood Hits	167	Shared Neighborhood Hits	54
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

EDD1_HUMAN
NC score	0.698935 (rank : 30)	θ value	1.62847e-25 (rank : 29)
Query Neighborhood Hits	406	Target Neighborhood Hits	170	Shared Neighborhood Hits	52
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

HERC2_MOUSE
NC score	0.626794 (rank : 31)	θ value	1.52067e-31 (rank : 25)
Query Neighborhood Hits	406	Target Neighborhood Hits	167	Shared Neighborhood Hits	41
SwissProt Accessions	Q4U2R1, O88473, Q3TRJ8, Q3TS47, Q3TST2, Q3UFQ6, Q3URH7, Q5DU32, Q7TPR5, Q80VV7, Q9QYT1, Q9Z168, Q9Z171	Gene names	Herc2, jdf2, Kiaa0393, rjs
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

HERC2_HUMAN
NC score	0.622474 (rank : 32)	θ value	5.77852e-31 (rank : 26)
Query Neighborhood Hits	406	Target Neighborhood Hits	163	Shared Neighborhood Hits	40
SwissProt Accessions	O95714, Q86SV7, Q86SV8, Q86SV9, Q86YY3, Q86YY4, Q86YY5, Q86YY6, Q86YY7, Q86YY8, Q86YY9, Q86YZ0, Q86YZ1	Gene names	HERC2
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

HECD1_HUMAN
NC score	0.556719 (rank : 33)	θ value	2.06002e-20 (rank : 33)
Query Neighborhood Hits	406	Target Neighborhood Hits	371	Shared Neighborhood Hits	47
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

YAP1_MOUSE
NC score	0.313470 (rank : 34)	θ value	θ > 10 (rank : 505)
Query Neighborhood Hits	406	Target Neighborhood Hits	96	Shared Neighborhood Hits	25
SwissProt Accessions	P46938, Q52KJ5	Gene names	Yap1, Yap, Yap65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

SAV1_MOUSE
NC score	0.281955 (rank : 35)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	406	Target Neighborhood Hits	48	Shared Neighborhood Hits	14
SwissProt Accessions	Q8VEB2, Q9D9N9, Q9ER46	Gene names	Sav1, Ww45, Wwp3
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (mWW45).

SAV1_HUMAN
NC score	0.281895 (rank : 36)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	406	Target Neighborhood Hits	51	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H4B6, Q6IA58, Q9H949, Q9HAK9	Gene names	SAV1, WW45
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (hWW45).

PINL_HUMAN
NC score	0.263159 (rank : 37)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	406	Target Neighborhood Hits	47	Shared Neighborhood Hits	15
SwissProt Accessions	O15428	Gene names	PIN1L
Domain Architecture
Description	PIN1-like protein.

WWC1_HUMAN
NC score	0.239980 (rank : 38)	θ value	θ > 10 (rank : 498)
Query Neighborhood Hits	406	Target Neighborhood Hits	290	Shared Neighborhood Hits	37
SwissProt Accessions	Q8IX03, O94946, Q6MZX4, Q6Y2F8, Q7Z4G8, Q8WVM4, Q9BT29	Gene names	WWC1, KIAA0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA) (HBeAg-binding protein 3).

WWC1_MOUSE
NC score	0.239427 (rank : 39)	θ value	θ > 10 (rank : 499)
Query Neighborhood Hits	406	Target Neighborhood Hits	290	Shared Neighborhood Hits	31
SwissProt Accessions	Q5SXA9, Q571D0, Q8K1Y3, Q8VD17, Q922W3	Gene names	Wwc1, Kiaa0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA).

BAG3_HUMAN
NC score	0.223765 (rank : 40)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	406	Target Neighborhood Hits	314	Shared Neighborhood Hits	50
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

PIN1_HUMAN
NC score	0.221015 (rank : 41)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	406	Target Neighborhood Hits	59	Shared Neighborhood Hits	13
SwissProt Accessions	Q13526	Gene names	PIN1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

PIN1_MOUSE
NC score	0.220271 (rank : 42)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	406	Target Neighborhood Hits	60	Shared Neighborhood Hits	15
SwissProt Accessions	Q9QUR7, Q543B3	Gene names	Pin1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

WWOX_HUMAN
NC score	0.218677 (rank : 43)	θ value	θ > 10 (rank : 500)
Query Neighborhood Hits	406	Target Neighborhood Hits	115	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NZC7, Q5MYT5, Q96KM3, Q96RF2, Q9BTT8, Q9NPC9, Q9NRF4, Q9NRF5, Q9NRF6, Q9NRK1, Q9NZC5	Gene names	WWOX, FOR, WOX1
Domain Architecture	No domain graphic available
Description	WW domain-containing oxidoreductase (EC 1.1.1.-) (Fragile site FRA16D oxidoreductase).

WWOX_MOUSE
NC score	0.216763 (rank : 44)	θ value	θ > 10 (rank : 501)
Query Neighborhood Hits	406	Target Neighborhood Hits	118	Shared Neighborhood Hits	14
SwissProt Accessions	Q91WL8, Q8C8J6, Q920Y2, Q9D2B3, Q9D339, Q9JLF5	Gene names	Wwox, Wox1
Domain Architecture	No domain graphic available
Description	WW domain-containing oxidoreductase (EC 1.1.1.-).

BAG3_MOUSE
NC score	0.194432 (rank : 45)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	406	Target Neighborhood Hits	513	Shared Neighborhood Hits	67
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

WWTR1_MOUSE
NC score	0.191372 (rank : 46)	θ value	θ > 10 (rank : 503)
Query Neighborhood Hits	406	Target Neighborhood Hits	54	Shared Neighborhood Hits	14
SwissProt Accessions	Q9EPK5, Q99KI4	Gene names	Wwtr1, Taz
Domain Architecture	No domain graphic available
Description	WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif).

WWTR1_HUMAN
NC score	0.189056 (rank : 47)	θ value	θ > 10 (rank : 502)
Query Neighborhood Hits	406	Target Neighborhood Hits	76	Shared Neighborhood Hits	18
SwissProt Accessions	Q9GZV5, Q8N3P2, Q9Y3W6	Gene names	WWTR1, TAZ
Domain Architecture	No domain graphic available
Description	WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif).

YAP1_HUMAN
NC score	0.185362 (rank : 48)	θ value	θ > 10 (rank : 504)
Query Neighborhood Hits	406	Target Neighborhood Hits	173	Shared Neighborhood Hits	34
SwissProt Accessions	P46937	Gene names	YAP1, YAP65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

PKHA5_HUMAN
NC score	0.166371 (rank : 49)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	406	Target Neighborhood Hits	455	Shared Neighborhood Hits	49
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

MAGI2_MOUSE
NC score	0.161880 (rank : 50)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	406	Target Neighborhood Hits	370	Shared Neighborhood Hits	42
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

MAGI2_HUMAN
NC score	0.153519 (rank : 51)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	406	Target Neighborhood Hits	373	Shared Neighborhood Hits	44
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

MAGI1_MOUSE
NC score	0.150989 (rank : 52)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	406	Target Neighborhood Hits	403	Shared Neighborhood Hits	40
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

MAGI1_HUMAN
NC score	0.149824 (rank : 53)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	406	Target Neighborhood Hits	388	Shared Neighborhood Hits	39
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

GAS7_HUMAN
NC score	0.142755 (rank : 54)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	406	Target Neighborhood Hits	258	Shared Neighborhood Hits	28
SwissProt Accessions	O60861, O43144	Gene names	GAS7, KIAA0394
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

GAS7_MOUSE
NC score	0.140428 (rank : 55)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	406	Target Neighborhood Hits	259	Shared Neighborhood Hits	27
SwissProt Accessions	Q60780, Q9QY25, Q9QY26, Q9QY34	Gene names	Gas7
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

PRP40_MOUSE
NC score	0.132880 (rank : 56)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	406	Target Neighborhood Hits	447	Shared Neighborhood Hits	57
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

PRP40_HUMAN
NC score	0.132588 (rank : 57)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	406	Target Neighborhood Hits	442	Shared Neighborhood Hits	54
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

RPGR_HUMAN
NC score	0.119478 (rank : 58)	θ value	0.0252991 (rank : 63)
Query Neighborhood Hits	406	Target Neighborhood Hits	279	Shared Neighborhood Hits	38
SwissProt Accessions	Q92834, O00702, O00737, Q8N5T6, Q93039, Q9HD29, Q9UMR1	Gene names	RPGR, RP3, XLRP3
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator.

AKA12_HUMAN
NC score	0.109257 (rank : 59)	θ value	0.000602161 (rank : 40)
Query Neighborhood Hits	406	Target Neighborhood Hits	825	Shared Neighborhood Hits	111
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

LEO1_HUMAN
NC score	0.103262 (rank : 60)	θ value	1.09739e-05 (rank : 34)
Query Neighborhood Hits	406	Target Neighborhood Hits	958	Shared Neighborhood Hits	113
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

BSCL2_HUMAN
NC score	0.103027 (rank : 61)	θ value	0.00665767 (rank : 46)
Query Neighborhood Hits	406	Target Neighborhood Hits	148	Shared Neighborhood Hits	30
SwissProt Accessions	Q96G97, Q96SV1, Q9BSQ0	Gene names	BSCL2
Domain Architecture	No domain graphic available
Description	Seipin (Bernardinelli-Seip congenital lipodystrophy type 2 protein).

APBB2_HUMAN
NC score	0.102687 (rank : 62)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	406	Target Neighborhood Hits	96	Shared Neighborhood Hits	23
SwissProt Accessions	Q92870, Q8IUI6	Gene names	APBB2, FE65L, FE65L1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2 (Fe65-like protein).

LEO1_MOUSE
NC score	0.100589 (rank : 63)	θ value	1.43324e-05 (rank : 36)
Query Neighborhood Hits	406	Target Neighborhood Hits	946	Shared Neighborhood Hits	109
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

RPGR_MOUSE
NC score	0.100003 (rank : 64)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	406	Target Neighborhood Hits	281	Shared Neighborhood Hits	39
SwissProt Accessions	Q9R0X5, O88408, Q9CU92	Gene names	Rpgr
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator (mRpgr).

APBB2_MOUSE
NC score	0.099533 (rank : 65)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	406	Target Neighborhood Hits	88	Shared Neighborhood Hits	23
SwissProt Accessions	Q9DBR4, Q6DFX8	Gene names	Apbb2
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2.

TXND2_HUMAN
NC score	0.098663 (rank : 66)	θ value	1.09739e-05 (rank : 35)
Query Neighborhood Hits	406	Target Neighborhood Hits	793	Shared Neighborhood Hits	100
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

SRGEF_HUMAN
NC score	0.095956 (rank : 67)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	406	Target Neighborhood Hits	33	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UGK8, Q9UGK9	Gene names	SERGEF, DELGEF, GNEFR
Domain Architecture	No domain graphic available
Description	Secretion-regulating guanine nucleotide exchange factor (Guanine nucleotide exchange factor-related protein) (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF).

CN155_HUMAN
NC score	0.095348 (rank : 68)	θ value	0.279714 (rank : 104)
Query Neighborhood Hits	406	Target Neighborhood Hits	385	Shared Neighborhood Hits	69
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

NSBP1_MOUSE
NC score	0.095186 (rank : 69)	θ value	0.0113563 (rank : 51)
Query Neighborhood Hits	406	Target Neighborhood Hits	681	Shared Neighborhood Hits	91
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

SRGEF_MOUSE
NC score	0.092791 (rank : 70)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	406	Target Neighborhood Hits	37	Shared Neighborhood Hits	8
SwissProt Accessions	Q80YD6, Q9QXB7	Gene names	Sergef, Delgef, Gnefr
Domain Architecture	No domain graphic available
Description	Secretion-regulating guanine nucleotide exchange factor (Guanine nucleotide exchange factor-related protein) (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF).

STXB4_HUMAN
NC score	0.091753 (rank : 71)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	406	Target Neighborhood Hits	616	Shared Neighborhood Hits	41
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

RCC2_HUMAN
NC score	0.091363 (rank : 72)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	406	Target Neighborhood Hits	36	Shared Neighborhood Hits	8
SwissProt Accessions	Q9P258, Q8IVL9, Q9BSN6, Q9NPV8	Gene names	RCC2, KIAA1470, TD60
Domain Architecture	No domain graphic available
Description	Protein RCC2 (Telophase disk protein of 60 kDa) (RCC1-like protein TD- 60).

STXB4_MOUSE
NC score	0.090965 (rank : 73)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	406	Target Neighborhood Hits	629	Shared Neighborhood Hits	43
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

RCC2_MOUSE
NC score	0.090704 (rank : 74)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	406	Target Neighborhood Hits	37	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BK67, Q6ZPQ0	Gene names	Rcc2, Kiaa1470
Domain Architecture	No domain graphic available
Description	Protein RCC2.

SETD2_HUMAN
NC score	0.090212 (rank : 75)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	406	Target Neighborhood Hits	412	Shared Neighborhood Hits	65
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SGP50_MOUSE
NC score	0.089386 (rank : 76)	θ value	0.279714 (rank : 108)
Query Neighborhood Hits	406	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q02596	Gene names	Glycam1
Domain Architecture
Description	Sulfated 50 kDa glycoprotein precursor (SGP50) (Endothelial ligand FOR L-selectin) (Glycosylation-dependent cell adhesion molecule 1) (GlyCAM-1) (MC26).

PCLO_HUMAN
NC score	0.089347 (rank : 77)	θ value	1.81305 (rank : 186)
Query Neighborhood Hits	406	Target Neighborhood Hits	2046	Shared Neighborhood Hits	178
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

RCC1_HUMAN
NC score	0.088867 (rank : 78)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	406	Target Neighborhood Hits	47	Shared Neighborhood Hits	6
SwissProt Accessions	P18754	Gene names	RCC1, CHC1
Domain Architecture
Description	Regulator of chromosome condensation (Chromosome condensation protein 1) (Cell cycle regulatory protein).

DMP1_HUMAN
NC score	0.087131 (rank : 79)	θ value	0.813845 (rank : 139)
Query Neighborhood Hits	406	Target Neighborhood Hits	491	Shared Neighborhood Hits	90
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

RCC1_MOUSE
NC score	0.086730 (rank : 80)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	406	Target Neighborhood Hits	45	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VE37, Q3UDB6	Gene names	Rcc1, Chc1
Domain Architecture	No domain graphic available
Description	Regulator of chromosome condensation (Chromosome condensation protein 1).

TGON2_HUMAN
NC score	0.085714 (rank : 81)	θ value	0.0330416 (rank : 67)
Query Neighborhood Hits	406	Target Neighborhood Hits	1037	Shared Neighborhood Hits	123
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

ERIC1_HUMAN
NC score	0.085464 (rank : 82)	θ value	0.0252991 (rank : 61)
Query Neighborhood Hits	406	Target Neighborhood Hits	364	Shared Neighborhood Hits	55
SwissProt Accessions	Q86X53, Q9P063	Gene names	ERICH1
Domain Architecture	No domain graphic available
Description	Glutamate-rich protein 1.

NACAM_MOUSE
NC score	0.085126 (rank : 83)	θ value	0.00175202 (rank : 42)
Query Neighborhood Hits	406	Target Neighborhood Hits	1866	Shared Neighborhood Hits	164
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

WBS16_MOUSE
NC score	0.084711 (rank : 84)	θ value	θ > 10 (rank : 497)
Query Neighborhood Hits	406	Target Neighborhood Hits	31	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CYF5	Gene names	Wbscr16
Domain Architecture	No domain graphic available
Description	Williams-Beuren syndrome chromosome region 16 protein homolog.

DSPP_HUMAN
NC score	0.084517 (rank : 85)	θ value	0.0961366 (rank : 77)
Query Neighborhood Hits	406	Target Neighborhood Hits	645	Shared Neighborhood Hits	100
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

IWS1_MOUSE
NC score	0.084104 (rank : 86)	θ value	0.00665767 (rank : 47)
Query Neighborhood Hits	406	Target Neighborhood Hits	1258	Shared Neighborhood Hits	144
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

TP53B_HUMAN
NC score	0.083684 (rank : 87)	θ value	0.00175202 (rank : 43)
Query Neighborhood Hits	406	Target Neighborhood Hits	413	Shared Neighborhood Hits	73
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

MUC7_HUMAN
NC score	0.083460 (rank : 88)	θ value	0.47712 (rank : 124)
Query Neighborhood Hits	406	Target Neighborhood Hits	538	Shared Neighborhood Hits	91
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

UN13A_HUMAN
NC score	0.083349 (rank : 89)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	406	Target Neighborhood Hits	285	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

TXND2_MOUSE
NC score	0.083199 (rank : 90)	θ value	0.00509761 (rank : 45)
Query Neighborhood Hits	406	Target Neighborhood Hits	828	Shared Neighborhood Hits	92
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

WBS16_HUMAN
NC score	0.083144 (rank : 91)	θ value	θ > 10 (rank : 496)
Query Neighborhood Hits	406	Target Neighborhood Hits	29	Shared Neighborhood Hits	6
SwissProt Accessions	Q96I51, Q548B1, Q9H0G7	Gene names	WBSCR16
Domain Architecture	No domain graphic available
Description	Williams-Beuren syndrome chromosome region 16 protein (RCC1-like G exchanging factor-like protein).

PRG4_HUMAN
NC score	0.082031 (rank : 92)	θ value	0.00869519 (rank : 49)
Query Neighborhood Hits	406	Target Neighborhood Hits	764	Shared Neighborhood Hits	112
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PCLO_MOUSE
NC score	0.081631 (rank : 93)	θ value	2.36792 (rank : 207)
Query Neighborhood Hits	406	Target Neighborhood Hits	2275	Shared Neighborhood Hits	173
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

IWS1_HUMAN
NC score	0.079987 (rank : 94)	θ value	0.279714 (rank : 105)
Query Neighborhood Hits	406	Target Neighborhood Hits	1241	Shared Neighborhood Hits	141
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

NU214_HUMAN
NC score	0.079894 (rank : 95)	θ value	0.0961366 (rank : 78)
Query Neighborhood Hits	406	Target Neighborhood Hits	657	Shared Neighborhood Hits	85
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

MUC1_MOUSE
NC score	0.078886 (rank : 96)	θ value	1.81305 (rank : 182)
Query Neighborhood Hits	406	Target Neighborhood Hits	388	Shared Neighborhood Hits	72
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

FA62A_MOUSE
NC score	0.078850 (rank : 97)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	406	Target Neighborhood Hits	155	Shared Neighborhood Hits	16
SwissProt Accessions	Q3U7R1, Q8C8R1, Q91X62, Q9CVH0, Q9Z1X5, Q9Z1X6	Gene names	Fam62a, Mbc2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

PTMA_HUMAN
NC score	0.078462 (rank : 98)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	406	Target Neighborhood Hits	88	Shared Neighborhood Hits	40
SwissProt Accessions	P06454, Q15249, Q15592	Gene names	PTMA, TMSA
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha-1].

MATR3_MOUSE
NC score	0.077674 (rank : 99)	θ value	0.0148317 (rank : 54)
Query Neighborhood Hits	406	Target Neighborhood Hits	321	Shared Neighborhood Hits	43
SwissProt Accessions	Q8K310	Gene names	Matr3
Domain Architecture	No domain graphic available
Description	Matrin-3.

TP53B_MOUSE
NC score	0.076218 (rank : 100)	θ value	0.47712 (rank : 126)
Query Neighborhood Hits	406	Target Neighborhood Hits	644	Shared Neighborhood Hits	100
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

PTMA_MOUSE
NC score	0.076181 (rank : 101)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	406	Target Neighborhood Hits	73	Shared Neighborhood Hits	34
SwissProt Accessions	P26350, Q3UQV6	Gene names	Ptma
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha].

UN13B_HUMAN
NC score	0.074652 (rank : 102)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	406	Target Neighborhood Hits	217	Shared Neighborhood Hits	16
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

UN13B_MOUSE
NC score	0.074472 (rank : 103)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	406	Target Neighborhood Hits	210	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

RCBT2_MOUSE
NC score	0.074188 (rank : 104)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	406	Target Neighborhood Hits	156	Shared Neighborhood Hits	11
SwissProt Accessions	Q99LJ7, Q3TUA3, Q8BMG2	Gene names	Rcbtb2, Chc1l
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 2 (Regulator of chromosome condensation and BTB domain-containing protein 2) (Chromosome condensation 1-like).

DMP1_MOUSE
NC score	0.074009 (rank : 105)	θ value	6.88961 (rank : 324)
Query Neighborhood Hits	406	Target Neighborhood Hits	498	Shared Neighborhood Hits	98
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

BRD8_MOUSE
NC score	0.073048 (rank : 106)	θ value	0.0148317 (rank : 53)
Query Neighborhood Hits	406	Target Neighborhood Hits	422	Shared Neighborhood Hits	58
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

RCBT2_HUMAN
NC score	0.073010 (rank : 107)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	406	Target Neighborhood Hits	158	Shared Neighborhood Hits	10
SwissProt Accessions	O95199	Gene names	RCBTB2, CHC1L, RLG
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 2 (Regulator of chromosome condensation and BTB domain-containing protein 2) (Chromosome condensation 1-like) (CHC1-L) (RCC1-like G exchanging factor).

SET1A_HUMAN
NC score	0.072898 (rank : 108)	θ value	1.81305 (rank : 191)
Query Neighborhood Hits	406	Target Neighborhood Hits	690	Shared Neighborhood Hits	103
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

ASPH_HUMAN
NC score	0.071380 (rank : 109)	θ value	0.0961366 (rank : 76)
Query Neighborhood Hits	406	Target Neighborhood Hits	158	Shared Neighborhood Hits	23
SwissProt Accessions	Q12797	Gene names	ASPH
Domain Architecture
Description	Aspartyl/asparaginyl beta-hydroxylase (EC 1.14.11.16) (Aspartate beta- hydroxylase) (ASP beta-hydroxylase) (Peptide-aspartate beta- dioxygenase).

NSBP1_HUMAN
NC score	0.070847 (rank : 110)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	406	Target Neighborhood Hits	251	Shared Neighborhood Hits	58
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

APBB3_MOUSE
NC score	0.070247 (rank : 111)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	406	Target Neighborhood Hits	32	Shared Neighborhood Hits	13
SwissProt Accessions	Q8R1C9	Gene names	Apbb3
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 3.

APBB3_HUMAN
NC score	0.069899 (rank : 112)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	406	Target Neighborhood Hits	36	Shared Neighborhood Hits	13
SwissProt Accessions	O95704, Q9NYX6, Q9NYX7, Q9NYX8	Gene names	APBB3, FE65L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 3 (Fe65-like protein 2) (Fe65L2).

TCOF_HUMAN
NC score	0.068628 (rank : 113)	θ value	6.88961 (rank : 355)
Query Neighborhood Hits	406	Target Neighborhood Hits	543	Shared Neighborhood Hits	97
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

RHG12_MOUSE
NC score	0.068491 (rank : 114)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	406	Target Neighborhood Hits	204	Shared Neighborhood Hits	19
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

CK024_MOUSE
NC score	0.068420 (rank : 115)	θ value	0.163984 (rank : 85)
Query Neighborhood Hits	406	Target Neighborhood Hits	307	Shared Neighborhood Hits	55
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

NASP_HUMAN
NC score	0.068230 (rank : 116)	θ value	0.62314 (rank : 134)
Query Neighborhood Hits	406	Target Neighborhood Hits	709	Shared Neighborhood Hits	97
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

FA62A_HUMAN
NC score	0.068011 (rank : 117)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	406	Target Neighborhood Hits	168	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BSJ8, O94848, Q6PJN4, Q9H6J1, Q9H6W2, Q9Y416	Gene names	FAM62A, KIAA0747, MBC2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

CUL7_HUMAN
NC score	0.067632 (rank : 118)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	406	Target Neighborhood Hits	41	Shared Neighborhood Hits	5
SwissProt Accessions	Q14999, Q5T654	Gene names	CUL7, KIAA0076
Domain Architecture
Description	Cullin-7 (CUL-7).

TF2AY_MOUSE
NC score	0.067421 (rank : 119)	θ value	0.0330416 (rank : 66)
Query Neighborhood Hits	406	Target Neighborhood Hits	51	Shared Neighborhood Hits	12
SwissProt Accessions	Q8R4I4, Q99PM2, Q9DAF4	Gene names	Gtf2a1lf, Alf
Domain Architecture
Description	TFIIA-alpha and beta-like factor (General transcription factor II A, 1-like factor).

MUC13_MOUSE
NC score	0.067380 (rank : 120)	θ value	2.36792 (rank : 205)
Query Neighborhood Hits	406	Target Neighborhood Hits	447	Shared Neighborhood Hits	54
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

RCBT1_MOUSE
NC score	0.067354 (rank : 121)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	406	Target Neighborhood Hits	157	Shared Neighborhood Hits	9
SwissProt Accessions	Q6NXM2, Q8BTZ6, Q8BZV0	Gene names	Rcbtb1
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 1 (Regulator of chromosome condensation and BTB domain-containing protein 1).

NCOR2_HUMAN
NC score	0.067137 (rank : 122)	θ value	0.125558 (rank : 83)
Query Neighborhood Hits	406	Target Neighborhood Hits	870	Shared Neighborhood Hits	104
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

ATX2_MOUSE
NC score	0.066734 (rank : 123)	θ value	0.0193708 (rank : 56)
Query Neighborhood Hits	406	Target Neighborhood Hits	445	Shared Neighborhood Hits	64
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

MDC1_HUMAN
NC score	0.066431 (rank : 124)	θ value	3.0926 (rank : 236)
Query Neighborhood Hits	406	Target Neighborhood Hits	1446	Shared Neighborhood Hits	155
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

WBP4_MOUSE
NC score	0.066293 (rank : 125)	θ value	θ > 10 (rank : 495)
Query Neighborhood Hits	406	Target Neighborhood Hits	100	Shared Neighborhood Hits	24
SwissProt Accessions	Q61048, Q8K1Z9, Q9CS45	Gene names	Wbp4, Fbp21, Fnbp21
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 4 (WBP-4) (Formin-binding protein 21).

RTN4_HUMAN
NC score	0.065991 (rank : 126)	θ value	0.00869519 (rank : 50)
Query Neighborhood Hits	406	Target Neighborhood Hits	357	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

TCAL5_HUMAN
NC score	0.065889 (rank : 127)	θ value	0.00228821 (rank : 44)
Query Neighborhood Hits	406	Target Neighborhood Hits	806	Shared Neighborhood Hits	90
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

K1333_MOUSE
NC score	0.065846 (rank : 128)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	406	Target Neighborhood Hits	53	Shared Neighborhood Hits	16
SwissProt Accessions	Q5RJY2, Q6ZPT7, Q8BNA4	Gene names	Kiaa1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

CC47_MOUSE
NC score	0.065792 (rank : 129)	θ value	0.0252991 (rank : 60)
Query Neighborhood Hits	406	Target Neighborhood Hits	245	Shared Neighborhood Hits	31
SwissProt Accessions	Q9D024, Q3TSB5, Q3V1S7, Q8C5D9, Q920S6	Gene names	Ccdc47, Asp4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor (Adipocyte-specific protein 4).

RCBT1_HUMAN
NC score	0.065635 (rank : 130)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	406	Target Neighborhood Hits	158	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NDN9, Q969U9	Gene names	RCBTB1, CLLD7, E4.5
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 1 (Regulator of chromosome condensation and BTB domain-containing protein 1) (Chronic lymphocytic leukemia deletion region gene 7 protein) (CLL deletion region gene 7 protein).

VPS72_MOUSE
NC score	0.065367 (rank : 131)	θ value	0.279714 (rank : 110)
Query Neighborhood Hits	406	Target Neighborhood Hits	286	Shared Neighborhood Hits	34
SwissProt Accessions	Q62481, Q3U2N4, Q810A9, Q99K81	Gene names	Vps72, Tcfl1, Yl1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

REV1_MOUSE
NC score	0.065331 (rank : 132)	θ value	0.0193708 (rank : 58)
Query Neighborhood Hits	406	Target Neighborhood Hits	67	Shared Neighborhood Hits	17
SwissProt Accessions	Q920Q2, Q9QXV2	Gene names	Rev1l, Rev1
Domain Architecture	No domain graphic available
Description	DNA repair protein REV1 (EC 2.7.7.-) (Rev1-like terminal deoxycytidyl transferase).

RASL1_HUMAN
NC score	0.064479 (rank : 133)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	406	Target Neighborhood Hits	142	Shared Neighborhood Hits	11
SwissProt Accessions	O95294, Q52M03, Q96CC7	Gene names	RASAL1, RASAL
Domain Architecture
Description	RasGAP-activating-like protein 1.

BSCL2_MOUSE
NC score	0.064136 (rank : 134)	θ value	0.47712 (rank : 121)
Query Neighborhood Hits	406	Target Neighborhood Hits	94	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Z2E9, Q810B0, Q9JJC2, Q9JMF1	Gene names	Bscl2, Gng3lg
Domain Architecture	No domain graphic available
Description	Seipin (Bernardinelli-Seip congenital lipodystrophy type 2 protein homolog).

MAGE1_HUMAN
NC score	0.063887 (rank : 135)	θ value	9.29e-05 (rank : 37)
Query Neighborhood Hits	406	Target Neighborhood Hits	1389	Shared Neighborhood Hits	118
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MATR3_HUMAN
NC score	0.063696 (rank : 136)	θ value	0.163984 (rank : 89)
Query Neighborhood Hits	406	Target Neighborhood Hits	325	Shared Neighborhood Hits	51
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

ADDA_MOUSE
NC score	0.063424 (rank : 137)	θ value	0.00035302 (rank : 39)
Query Neighborhood Hits	406	Target Neighborhood Hits	198	Shared Neighborhood Hits	41
SwissProt Accessions	Q9QYC0, Q9JLE3	Gene names	Add1
Domain Architecture
Description	Alpha-adducin (Erythrocyte adducin subunit alpha).

DSPP_MOUSE
NC score	0.063063 (rank : 138)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	406	Target Neighborhood Hits	491	Shared Neighborhood Hits	90
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

VPS72_HUMAN
NC score	0.062924 (rank : 139)	θ value	0.279714 (rank : 109)
Query Neighborhood Hits	406	Target Neighborhood Hits	274	Shared Neighborhood Hits	32
SwissProt Accessions	Q15906, Q53GJ2, Q5U0R4	Gene names	VPS72, TCFL1, YL1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

BASP_HUMAN
NC score	0.062690 (rank : 140)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	406	Target Neighborhood Hits	321	Shared Neighborhood Hits	61
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

VCX3_HUMAN
NC score	0.062607 (rank : 141)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	406	Target Neighborhood Hits	105	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NNX9, Q9P0H4	Gene names	VCX3A, VCX3, VCX8R, VCXA
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 3 (VCX-A protein) (Variably charged protein X-A) (Variable charge protein on X with eight repeats) (VCX- 8r).

PODXL_HUMAN
NC score	0.062168 (rank : 142)	θ value	0.47712 (rank : 125)
Query Neighborhood Hits	406	Target Neighborhood Hits	191	Shared Neighborhood Hits	44
SwissProt Accessions	O00592	Gene names	PODXL, PCLP, PCLP1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

VCXC_HUMAN
NC score	0.061788 (rank : 143)	θ value	θ > 10 (rank : 494)
Query Neighborhood Hits	406	Target Neighborhood Hits	139	Shared Neighborhood Hits	41
SwissProt Accessions	Q9H321	Gene names	VCXC
Domain Architecture	No domain graphic available
Description	VCX-C protein (Variably charged protein X-C).

ATX2_HUMAN
NC score	0.061558 (rank : 144)	θ value	0.0252991 (rank : 59)
Query Neighborhood Hits	406	Target Neighborhood Hits	375	Shared Neighborhood Hits	46
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

BASP_MOUSE
NC score	0.061192 (rank : 145)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	406	Target Neighborhood Hits	260	Shared Neighborhood Hits	47
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

RASL1_MOUSE
NC score	0.060851 (rank : 146)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	406	Target Neighborhood Hits	148	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z268	Gene names	Rasal1, Rasal
Domain Architecture
Description	RasGAP-activating-like protein 1.

TCOF_MOUSE
NC score	0.060335 (rank : 147)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	406	Target Neighborhood Hits	471	Shared Neighborhood Hits	78
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

RHG12_HUMAN
NC score	0.059880 (rank : 148)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	406	Target Neighborhood Hits	190	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

TCRG1_MOUSE
NC score	0.059284 (rank : 149)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	406	Target Neighborhood Hits	947	Shared Neighborhood Hits	97
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

DOC2A_MOUSE
NC score	0.059147 (rank : 150)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	406	Target Neighborhood Hits	140	Shared Neighborhood Hits	12
SwissProt Accessions	Q7TNF0	Gene names	Doc2a
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha).

BRD8_HUMAN
NC score	0.059085 (rank : 151)	θ value	0.0330416 (rank : 64)
Query Neighborhood Hits	406	Target Neighborhood Hits	292	Shared Neighborhood Hits	37
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

NOLC1_HUMAN
NC score	0.059025 (rank : 152)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	406	Target Neighborhood Hits	452	Shared Neighborhood Hits	75
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

SRRM2_HUMAN
NC score	0.058719 (rank : 153)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	406	Target Neighborhood Hits	1296	Shared Neighborhood Hits	148
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

TCRG1_HUMAN
NC score	0.058407 (rank : 154)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	406	Target Neighborhood Hits	929	Shared Neighborhood Hits	85
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

MYCB2_HUMAN
NC score	0.058137 (rank : 155)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	406	Target Neighborhood Hits	390	Shared Neighborhood Hits	42
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

ALS2_HUMAN
NC score	0.058135 (rank : 156)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	406	Target Neighborhood Hits	121	Shared Neighborhood Hits	12
SwissProt Accessions	Q96Q42, Q8N1E0, Q96PC4, Q96Q41, Q9H973, Q9HCK9	Gene names	ALS2, KIAA1563
Domain Architecture
Description	Alsin (Amyotrophic lateral sclerosis protein 2).

NFH_MOUSE
NC score	0.058126 (rank : 157)	θ value	0.000158464 (rank : 38)
Query Neighborhood Hits	406	Target Neighborhood Hits	2247	Shared Neighborhood Hits	182
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

RASL2_HUMAN
NC score	0.057913 (rank : 158)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	406	Target Neighborhood Hits	161	Shared Neighborhood Hits	11
SwissProt Accessions	O43374, O60286, Q86UW3, Q96QU0	Gene names	RASA4, CAPRI, GAPL, KIAA0538
Domain Architecture
Description	Ras GTPase-activating protein 4 (RasGAP-activating-like protein 2) (Calcium-promoted Ras inactivator).

PERP_MOUSE
NC score	0.057804 (rank : 159)	θ value	0.163984 (rank : 91)
Query Neighborhood Hits	406	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JK95, Q9JI77	Gene names	Perp, Krtcap1
Domain Architecture	No domain graphic available
Description	p53 apoptosis effector related to PMP-22 (Keratinocytes-associated protein 1) (KCP-1).

PTMS_MOUSE
NC score	0.056946 (rank : 160)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	406	Target Neighborhood Hits	68	Shared Neighborhood Hits	25
SwissProt Accessions	Q9D0J8	Gene names	Ptms
Domain Architecture	No domain graphic available
Description	Parathymosin.

TOLIP_MOUSE
NC score	0.056729 (rank : 161)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	406	Target Neighborhood Hits	24	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QZ06, Q543N1, Q9D5P5	Gene names	Tollip
Domain Architecture
Description	Toll-interacting protein.

NEUM_MOUSE
NC score	0.056719 (rank : 162)	θ value	8.99809 (rank : 388)
Query Neighborhood Hits	406	Target Neighborhood Hits	149	Shared Neighborhood Hits	41
SwissProt Accessions	P06837	Gene names	Gap43, Basp2
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (Calmodulin-binding protein P-57).

TARA_HUMAN
NC score	0.056705 (rank : 163)	θ value	0.62314 (rank : 136)
Query Neighborhood Hits	406	Target Neighborhood Hits	1626	Shared Neighborhood Hits	137
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

DRP2_HUMAN
NC score	0.056699 (rank : 164)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	406	Target Neighborhood Hits	186	Shared Neighborhood Hits	27
SwissProt Accessions	Q13474	Gene names	DRP2
Domain Architecture
Description	Dystrophin-related protein 2.

ZN750_MOUSE
NC score	0.056563 (rank : 165)	θ value	0.21417 (rank : 101)
Query Neighborhood Hits	406	Target Neighborhood Hits	346	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

CS016_HUMAN
NC score	0.056560 (rank : 166)	θ value	0.62314 (rank : 131)
Query Neighborhood Hits	406	Target Neighborhood Hits	310	Shared Neighborhood Hits	54
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

PELP1_HUMAN
NC score	0.056491 (rank : 167)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	406	Target Neighborhood Hits	596	Shared Neighborhood Hits	96
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

DOC2A_HUMAN
NC score	0.056489 (rank : 168)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	406	Target Neighborhood Hits	144	Shared Neighborhood Hits	14
SwissProt Accessions	Q14183, Q6P4G4, Q7Z5G0, Q8IVX0	Gene names	DOC2A
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha) (Doc2).

ALS2_MOUSE
NC score	0.056119 (rank : 169)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	406	Target Neighborhood Hits	111	Shared Neighborhood Hits	8
SwissProt Accessions	Q920R0, Q8JZR1, Q9CXJ3	Gene names	Als2
Domain Architecture
Description	Alsin (Amyotrophic lateral sclerosis protein 2 homolog).

SRRM2_MOUSE
NC score	0.055959 (rank : 170)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	406	Target Neighborhood Hits	1470	Shared Neighborhood Hits	148
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

PRG4_MOUSE
NC score	0.055751 (rank : 171)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	406	Target Neighborhood Hits	624	Shared Neighborhood Hits	88
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

VCX1_HUMAN
NC score	0.055322 (rank : 172)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	406	Target Neighborhood Hits	129	Shared Neighborhood Hits	37
SwissProt Accessions	Q9H320, Q9P0H3	Gene names	VCX, VCX1, VCX10R, VCXB1
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 1 (VCX-B1 protein) (Variably charged protein X-B1) (Variable charge protein on X with ten repeats) (VCX- 10r).

APC10_HUMAN
NC score	0.055103 (rank : 173)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	406	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UM13, Q2V500, Q9UG51, Q9Y5R0	Gene names	ANAPC10, APC10
Domain Architecture
Description	Anaphase-promoting complex subunit 10 (APC10) (Cyclosome subunit 10).

PARC_MOUSE
NC score	0.055054 (rank : 174)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	406	Target Neighborhood Hits	114	Shared Neighborhood Hits	17
SwissProt Accessions	Q80TT8, Q8BKL9, Q8CGC0, Q8R363	Gene names	Parc, Kiaa0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein.

MYCB2_MOUSE
NC score	0.054829 (rank : 175)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	406	Target Neighborhood Hits	307	Shared Neighborhood Hits	36
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

DOC2B_HUMAN
NC score	0.054807 (rank : 176)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	406	Target Neighborhood Hits	150	Shared Neighborhood Hits	14
SwissProt Accessions	Q14184	Gene names	DOC2B
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

SELPL_MOUSE
NC score	0.054756 (rank : 177)	θ value	0.813845 (rank : 148)
Query Neighborhood Hits	406	Target Neighborhood Hits	588	Shared Neighborhood Hits	80
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

RTN4_MOUSE
NC score	0.054675 (rank : 178)	θ value	3.0926 (rank : 244)
Query Neighborhood Hits	406	Target Neighborhood Hits	341	Shared Neighborhood Hits	57
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

DOC2B_MOUSE
NC score	0.054395 (rank : 179)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	406	Target Neighborhood Hits	169	Shared Neighborhood Hits	16
SwissProt Accessions	P70169, Q6NXK3	Gene names	Doc2b
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

TOLIP_HUMAN
NC score	0.054366 (rank : 180)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	406	Target Neighborhood Hits	20	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H0E2, Q9H9E6, Q9UJ69	Gene names	TOLLIP
Domain Architecture
Description	Toll-interacting protein.

MAP1B_MOUSE
NC score	0.054260 (rank : 181)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	406	Target Neighborhood Hits	977	Shared Neighborhood Hits	126
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

PA24B_MOUSE
NC score	0.054026 (rank : 182)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	406	Target Neighborhood Hits	102	Shared Neighborhood Hits	11
SwissProt Accessions	Q4QQM1, Q80VV8, Q91W88	Gene names	Pla2g4b
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

RIMS2_HUMAN
NC score	0.053608 (rank : 183)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	406	Target Neighborhood Hits	342	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

T2FA_HUMAN
NC score	0.053280 (rank : 184)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	406	Target Neighborhood Hits	228	Shared Neighborhood Hits	59
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

NEUM_HUMAN
NC score	0.052938 (rank : 185)	θ value	5.27518 (rank : 306)
Query Neighborhood Hits	406	Target Neighborhood Hits	132	Shared Neighborhood Hits	40
SwissProt Accessions	P17677	Gene names	GAP43
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (PP46) (Neural phosphoprotein B-50).

APC10_MOUSE
NC score	0.052847 (rank : 186)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	406	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K2H6, Q9CW24	Gene names	Anapc10, Apc10
Domain Architecture
Description	Anaphase-promoting complex subunit 10 (APC10) (Cyclosome subunit 10).

RP1L1_HUMAN
NC score	0.052564 (rank : 187)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	406	Target Neighborhood Hits	1072	Shared Neighborhood Hits	142
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

REV1_HUMAN
NC score	0.052292 (rank : 188)	θ value	0.21417 (rank : 99)
Query Neighborhood Hits	406	Target Neighborhood Hits	56	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UBZ9, O95941, Q9C0J4, Q9NUP2	Gene names	REV1L, REV1
Domain Architecture	No domain graphic available
Description	DNA repair protein REV1 (EC 2.7.7.-) (Rev1-like terminal deoxycytidyl transferase) (Alpha integrin-binding protein 80) (AIBP80).

LEUK_HUMAN
NC score	0.052219 (rank : 189)	θ value	0.163984 (rank : 88)
Query Neighborhood Hits	406	Target Neighborhood Hits	213	Shared Neighborhood Hits	42
SwissProt Accessions	P16150	Gene names	SPN, CD43
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Galactoglycoprotein) (GALGP) (CD43 antigen).

CQ028_MOUSE
NC score	0.052091 (rank : 190)	θ value	0.125558 (rank : 81)
Query Neighborhood Hits	406	Target Neighborhood Hits	54	Shared Neighborhood Hits	12
SwissProt Accessions	Q8R1F6, Q8C8V6	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C17orf28 homolog.

OGFR_MOUSE
NC score	0.052087 (rank : 191)	θ value	0.365318 (rank : 116)
Query Neighborhood Hits	406	Target Neighborhood Hits	584	Shared Neighborhood Hits	69
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

RIMS2_MOUSE
NC score	0.052050 (rank : 192)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	406	Target Neighborhood Hits	376	Shared Neighborhood Hits	37
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

APBB1_MOUSE
NC score	0.051725 (rank : 193)	θ value	1.06291 (rank : 150)
Query Neighborhood Hits	406	Target Neighborhood Hits	75	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QXJ1, O08642, Q3TPU0, Q8BNF4, Q8BSR9	Gene names	Apbb1, Fe65
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein).

MAP1B_HUMAN
NC score	0.051648 (rank : 194)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	406	Target Neighborhood Hits	903	Shared Neighborhood Hits	116
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

UN13D_HUMAN
NC score	0.051345 (rank : 195)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	406	Target Neighborhood Hits	117	Shared Neighborhood Hits	8
SwissProt Accessions	Q70J99, Q9H7K5	Gene names	UNC13D
Domain Architecture	No domain graphic available
Description	Unc-13 homolog D (Munc13-4).

APBB1_HUMAN
NC score	0.051166 (rank : 196)	θ value	0.813845 (rank : 138)
Query Neighborhood Hits	406	Target Neighborhood Hits	62	Shared Neighborhood Hits	15
SwissProt Accessions	O00213, Q96A93	Gene names	APBB1, FE65
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein).

SEC63_HUMAN
NC score	0.051085 (rank : 197)	θ value	0.0431538 (rank : 70)
Query Neighborhood Hits	406	Target Neighborhood Hits	586	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

PTMS_HUMAN
NC score	0.050971 (rank : 198)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	406	Target Neighborhood Hits	111	Shared Neighborhood Hits	32
SwissProt Accessions	P20962	Gene names	PTMS
Domain Architecture	No domain graphic available
Description	Parathymosin.

PARC_HUMAN
NC score	0.050898 (rank : 199)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	406	Target Neighborhood Hits	148	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IWT3, O75188, Q68CP2, Q68D92, Q8N3W9, Q9BU56	Gene names	PARC, H7AP1, KIAA0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein (UbcH7-associated protein 1).

FBX34_MOUSE
NC score	0.050846 (rank : 200)	θ value	0.0193708 (rank : 57)
Query Neighborhood Hits	406	Target Neighborhood Hits	100	Shared Neighborhood Hits	11
SwissProt Accessions	Q80XI1, Q9D290	Gene names	Fbxo34
Domain Architecture	No domain graphic available
Description	F-box only protein 34.

SON_HUMAN
NC score	0.050295 (rank : 201)	θ value	0.0148317 (rank : 55)
Query Neighborhood Hits	406	Target Neighborhood Hits	1568	Shared Neighborhood Hits	123
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

AMPH_HUMAN
NC score	0.048848 (rank : 202)	θ value	0.0431538 (rank : 68)
Query Neighborhood Hits	406	Target Neighborhood Hits	455	Shared Neighborhood Hits	59
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

RSF1_HUMAN
NC score	0.048725 (rank : 203)	θ value	1.81305 (rank : 189)
Query Neighborhood Hits	406	Target Neighborhood Hits	539	Shared Neighborhood Hits	78
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

K0460_MOUSE
NC score	0.048478 (rank : 204)	θ value	0.62314 (rank : 133)
Query Neighborhood Hits	406	Target Neighborhood Hits	374	Shared Neighborhood Hits	58
SwissProt Accessions	Q6NXI6, Q3U3L8, Q6ZQA7	Gene names	Kiaa0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

BPTF_HUMAN
NC score	0.048474 (rank : 205)	θ value	2.36792 (rank : 196)
Query Neighborhood Hits	406	Target Neighborhood Hits	786	Shared Neighborhood Hits	103
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

K0460_HUMAN
NC score	0.048257 (rank : 206)	θ value	0.279714 (rank : 106)
Query Neighborhood Hits	406	Target Neighborhood Hits	357	Shared Neighborhood Hits	51
SwissProt Accessions	Q5VT52, O75048, Q5VT53, Q6MZL4, Q86XD2	Gene names	KIAA0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

ADDB_MOUSE
NC score	0.048229 (rank : 207)	θ value	0.0961366 (rank : 75)
Query Neighborhood Hits	406	Target Neighborhood Hits	574	Shared Neighborhood Hits	75
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

TCAL3_HUMAN
NC score	0.047989 (rank : 208)	θ value	1.38821 (rank : 170)
Query Neighborhood Hits	406	Target Neighborhood Hits	274	Shared Neighborhood Hits	36
SwissProt Accessions	Q969E4	Gene names	TCEAL3
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 3 (TCEA-like protein 3) (Transcription elongation factor S-II protein-like 3).

NIPBL_HUMAN
NC score	0.047703 (rank : 209)	θ value	5.27518 (rank : 309)
Query Neighborhood Hits	406	Target Neighborhood Hits	1311	Shared Neighborhood Hits	129
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

RAG2_MOUSE
NC score	0.047405 (rank : 210)	θ value	0.279714 (rank : 107)
Query Neighborhood Hits	406	Target Neighborhood Hits	40	Shared Neighborhood Hits	8
SwissProt Accessions	P21784	Gene names	Rag2, Rag-2
Domain Architecture
Description	V(D)J recombination-activating protein 2 (RAG-2).

BSN_HUMAN
NC score	0.046972 (rank : 211)	θ value	0.21417 (rank : 94)
Query Neighborhood Hits	406	Target Neighborhood Hits	1537	Shared Neighborhood Hits	123
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

SEC63_MOUSE
NC score	0.046807 (rank : 212)	θ value	0.163984 (rank : 92)
Query Neighborhood Hits	406	Target Neighborhood Hits	601	Shared Neighborhood Hits	60
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

TF2AY_HUMAN
NC score	0.046558 (rank : 213)	θ value	1.06291 (rank : 159)
Query Neighborhood Hits	406	Target Neighborhood Hits	77	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UNN4	Gene names	GTF2A1LF, ALF
Domain Architecture
Description	TFIIA-alpha and beta-like factor (General transcription factor II A, 1-like factor).

NCKX1_HUMAN
NC score	0.046409 (rank : 214)	θ value	8.99809 (rank : 386)
Query Neighborhood Hits	406	Target Neighborhood Hits	223	Shared Neighborhood Hits	61
SwissProt Accessions	O60721, O43485, O75184	Gene names	SLC24A1, KIAA0702, NCKX1
Domain Architecture
Description	Sodium/potassium/calcium exchanger 1 (Na(+)/K(+)/Ca(2+)-exchange protein 1) (Retinal rod Na-Ca+K exchanger).

RGS3_MOUSE
NC score	0.045124 (rank : 215)	θ value	0.365318 (rank : 119)
Query Neighborhood Hits	406	Target Neighborhood Hits	1621	Shared Neighborhood Hits	130
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

BIN1_HUMAN
NC score	0.044137 (rank : 216)	θ value	1.81305 (rank : 172)
Query Neighborhood Hits	406	Target Neighborhood Hits	335	Shared Neighborhood Hits	51
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

RERE_HUMAN
NC score	0.044070 (rank : 217)	θ value	0.365318 (rank : 118)
Query Neighborhood Hits	406	Target Neighborhood Hits	779	Shared Neighborhood Hits	98
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

CASC3_MOUSE
NC score	0.043973 (rank : 218)	θ value	0.279714 (rank : 103)
Query Neighborhood Hits	406	Target Neighborhood Hits	333	Shared Neighborhood Hits	51
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

LEUK_MOUSE
NC score	0.043825 (rank : 219)	θ value	4.03905 (rank : 265)
Query Neighborhood Hits	406	Target Neighborhood Hits	147	Shared Neighborhood Hits	32
SwissProt Accessions	P15702	Gene names	Spn
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Ly- 48) (B cell differentiation antigen LP-3) (CD43 antigen).

MLL2_HUMAN
NC score	0.042525 (rank : 220)	θ value	3.0926 (rank : 237)
Query Neighborhood Hits	406	Target Neighborhood Hits	1788	Shared Neighborhood Hits	129
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MAP1A_HUMAN
NC score	0.042309 (rank : 221)	θ value	4.03905 (rank : 266)
Query Neighborhood Hits	406	Target Neighborhood Hits	1626	Shared Neighborhood Hits	143
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

NCOR1_MOUSE
NC score	0.041888 (rank : 222)	θ value	8.99809 (rank : 387)
Query Neighborhood Hits	406	Target Neighborhood Hits	521	Shared Neighborhood Hits	94
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

SRCA_MOUSE
NC score	0.041827 (rank : 223)	θ value	0.813845 (rank : 149)
Query Neighborhood Hits	406	Target Neighborhood Hits	212	Shared Neighborhood Hits	46
SwissProt Accessions	Q7TQ48, Q8BS43	Gene names	Srl, Sar
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

CQ028_HUMAN
NC score	0.041663 (rank : 224)	θ value	0.62314 (rank : 130)
Query Neighborhood Hits	406	Target Neighborhood Hits	56	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IV36, Q8N5L6, Q8TE83, Q9NT34	Gene names	C17orf28, DMC1
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C17orf28 (Down-regulated in multiple cancers- 1).

NCOR1_HUMAN
NC score	0.041543 (rank : 225)	θ value	1.06291 (rank : 157)
Query Neighborhood Hits	406	Target Neighborhood Hits	577	Shared Neighborhood Hits	93
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

POLI_MOUSE
NC score	0.040969 (rank : 226)	θ value	0.62314 (rank : 135)
Query Neighborhood Hits	406	Target Neighborhood Hits	27	Shared Neighborhood Hits	7
SwissProt Accessions	Q6R3M4, Q641P1, Q6R3M3, Q9R1A6	Gene names	Poli, Rad30b
Domain Architecture	No domain graphic available
Description	DNA polymerase iota (EC 2.7.7.7) (Rad30 homolog B).

POLI_HUMAN
NC score	0.040799 (rank : 227)	θ value	0.813845 (rank : 146)
Query Neighborhood Hits	406	Target Neighborhood Hits	28	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UNA4, Q8N590, Q9H0S1, Q9NYH6	Gene names	POLI, RAD30B
Domain Architecture	No domain graphic available
Description	DNA polymerase iota (EC 2.7.7.7) (RAD30 homolog B) (Eta2).

MYST3_MOUSE
NC score	0.040540 (rank : 228)	θ value	1.81305 (rank : 183)
Query Neighborhood Hits	406	Target Neighborhood Hits	688	Shared Neighborhood Hits	105
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

OXR1_MOUSE
NC score	0.039902 (rank : 229)	θ value	1.38821 (rank : 169)
Query Neighborhood Hits	406	Target Neighborhood Hits	516	Shared Neighborhood Hits	82
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

AKAP2_MOUSE
NC score	0.039609 (rank : 230)	θ value	0.47712 (rank : 120)
Query Neighborhood Hits	406	Target Neighborhood Hits	385	Shared Neighborhood Hits	55
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

DCP1A_HUMAN
NC score	0.039092 (rank : 231)	θ value	1.38821 (rank : 163)
Query Neighborhood Hits	406	Target Neighborhood Hits	228	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NPI6	Gene names	DCP1A, SMIF
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (Smad4-interacting transcriptional co-activator).

OSBL8_HUMAN
NC score	0.037962 (rank : 232)	θ value	0.0736092 (rank : 74)
Query Neighborhood Hits	406	Target Neighborhood Hits	289	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

XRCC1_MOUSE
NC score	0.037827 (rank : 233)	θ value	4.03905 (rank : 282)
Query Neighborhood Hits	406	Target Neighborhood Hits	242	Shared Neighborhood Hits	37
SwissProt Accessions	Q60596, Q3THC5, Q5U435, Q7TNQ5	Gene names	Xrcc1, Xrcc-1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

GP73_MOUSE
NC score	0.037757 (rank : 234)	θ value	0.21417 (rank : 96)
Query Neighborhood Hits	406	Target Neighborhood Hits	506	Shared Neighborhood Hits	42
SwissProt Accessions	Q91XA2	Gene names	Golph2
Domain Architecture	No domain graphic available
Description	Golgi phosphoprotein 2 (Golgi membrane protein GP73).

RBM25_HUMAN
NC score	0.037630 (rank : 235)	θ value	2.36792 (rank : 211)
Query Neighborhood Hits	406	Target Neighborhood Hits	682	Shared Neighborhood Hits	68
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

CFDP1_MOUSE
NC score	0.037350 (rank : 236)	θ value	6.88961 (rank : 323)
Query Neighborhood Hits	406	Target Neighborhood Hits	64	Shared Neighborhood Hits	17
SwissProt Accessions	O88271, O70565, Q9JMA5	Gene names	Cfdp1, Bcnt, Cfdp, Cp27
Domain Architecture	No domain graphic available
Description	Craniofacial development protein 1 (Bucentaur) (27 kDa craniofacial protein) (Protein Cp27).

MUC1_HUMAN
NC score	0.037085 (rank : 237)	θ value	0.163984 (rank : 90)
Query Neighborhood Hits	406	Target Neighborhood Hits	975	Shared Neighborhood Hits	76
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

CCD47_HUMAN
NC score	0.036885 (rank : 238)	θ value	4.03905 (rank : 256)
Query Neighborhood Hits	406	Target Neighborhood Hits	119	Shared Neighborhood Hits	13
SwissProt Accessions	Q96A33, Q96D00, Q96JZ7, Q9H3E4, Q9NRG3	Gene names	CCDC47
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor.

NSD1_MOUSE
NC score	0.036864 (rank : 239)	θ value	0.0431538 (rank : 69)
Query Neighborhood Hits	406	Target Neighborhood Hits	472	Shared Neighborhood Hits	49
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

ETV3_MOUSE
NC score	0.036843 (rank : 240)	θ value	0.0252991 (rank : 62)
Query Neighborhood Hits	406	Target Neighborhood Hits	128	Shared Neighborhood Hits	14
SwissProt Accessions	Q8R4Z4, Q9QZW1	Gene names	Etv3, Mets, Pe1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

E2F4_HUMAN
NC score	0.036816 (rank : 241)	θ value	0.163984 (rank : 87)
Query Neighborhood Hits	406	Target Neighborhood Hits	188	Shared Neighborhood Hits	21
SwissProt Accessions	Q16254, Q12991, Q15328	Gene names	E2F4
Domain Architecture
Description	Transcription factor E2F4 (E2F-4).

DMD_HUMAN
NC score	0.036739 (rank : 242)	θ value	3.0926 (rank : 226)
Query Neighborhood Hits	406	Target Neighborhood Hits	1135	Shared Neighborhood Hits	67
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

SAS10_MOUSE
NC score	0.036628 (rank : 243)	θ value	1.81305 (rank : 190)
Query Neighborhood Hits	406	Target Neighborhood Hits	81	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JI13, Q3UL95, Q8R5C6, Q9JJ12	Gene names	Crlz1, Crl1, Sas10
Domain Architecture	No domain graphic available
Description	Something about silencing protein 10 (Disrupter of silencing SAS10) (Charged amino acid-rich leucine zipper 1) (Crl-1).

SETBP_MOUSE
NC score	0.035846 (rank : 244)	θ value	5.27518 (rank : 317)
Query Neighborhood Hits	406	Target Neighborhood Hits	352	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

BIN1_MOUSE
NC score	0.035763 (rank : 245)	θ value	1.81305 (rank : 173)
Query Neighborhood Hits	406	Target Neighborhood Hits	283	Shared Neighborhood Hits	41
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

MINT_MOUSE
NC score	0.035659 (rank : 246)	θ value	6.88961 (rank : 339)
Query Neighborhood Hits	406	Target Neighborhood Hits	1514	Shared Neighborhood Hits	148
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

RD23B_MOUSE
NC score	0.035580 (rank : 247)	θ value	6.88961 (rank : 347)
Query Neighborhood Hits	406	Target Neighborhood Hits	189	Shared Neighborhood Hits	47
SwissProt Accessions	P54728	Gene names	Rad23b, Mhr23b
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (mHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

F10A5_HUMAN
NC score	0.035435 (rank : 248)	θ value	0.62314 (rank : 132)
Query Neighborhood Hits	406	Target Neighborhood Hits	277	Shared Neighborhood Hits	24
SwissProt Accessions	Q8NFI4	Gene names	FAM10A5
Domain Architecture	No domain graphic available
Description	Protein FAM10A5.

F10A1_HUMAN
NC score	0.035069 (rank : 249)	θ value	0.813845 (rank : 142)
Query Neighborhood Hits	406	Target Neighborhood Hits	312	Shared Neighborhood Hits	32
SwissProt Accessions	P50502, O14999	Gene names	ST13, FAM10A1, HIP, SNC6
Domain Architecture
Description	Hsc70-interacting protein (Hip) (Suppression of tumorigenicity protein 13) (Putative tumor suppressor ST13) (Protein FAM10A1) (Progesterone receptor-associated p48 protein) (NY-REN-33 antigen).

CCD82_HUMAN
NC score	0.034939 (rank : 250)	θ value	6.88961 (rank : 322)
Query Neighborhood Hits	406	Target Neighborhood Hits	137	Shared Neighborhood Hits	35
SwissProt Accessions	Q8N4S0, Q9H2Q5, Q9H5E3	Gene names	CCDC82
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 82.

EMSY_MOUSE
NC score	0.034828 (rank : 251)	θ value	3.0926 (rank : 228)
Query Neighborhood Hits	406	Target Neighborhood Hits	294	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BMB0, Q5FWK5, Q80XU1, Q8VDW9	Gene names	Emsy
Domain Architecture
Description	Protein EMSY.

BRCA1_MOUSE
NC score	0.034475 (rank : 252)	θ value	0.0736092 (rank : 72)
Query Neighborhood Hits	406	Target Neighborhood Hits	436	Shared Neighborhood Hits	27
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

RAG2_HUMAN
NC score	0.034315 (rank : 253)	θ value	2.36792 (rank : 210)
Query Neighborhood Hits	406	Target Neighborhood Hits	60	Shared Neighborhood Hits	9
SwissProt Accessions	P55895, Q8TBL4	Gene names	RAG2
Domain Architecture
Description	V(D)J recombination-activating protein 2 (RAG-2).

ZCC2_HUMAN
NC score	0.034096 (rank : 254)	θ value	0.279714 (rank : 111)
Query Neighborhood Hits	406	Target Neighborhood Hits	47	Shared Neighborhood Hits	5
SwissProt Accessions	Q7Z2W4, Q8IW57, Q8TAJ3, Q96N79, Q9H8R9, Q9P0Y7	Gene names	ZC3HAV1, ZC3HDC2
Domain Architecture
Description	Zinc finger CCCH type antiviral protein 1 (Zinc finger CCCH domain- containing protein 2).

RHBD3_MOUSE
NC score	0.033962 (rank : 255)	θ value	1.81305 (rank : 187)
Query Neighborhood Hits	406	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BP97, Q3U0Y4, Q5SUT5, Q5SUT6, Q5SUT7	Gene names	Rhbdd3
Domain Architecture	No domain graphic available
Description	Rhomboid domain-containing protein 3.

SETBP_HUMAN
NC score	0.033739 (rank : 256)	θ value	4.03905 (rank : 276)
Query Neighborhood Hits	406	Target Neighborhood Hits	305	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Y6X0, Q9UEF3	Gene names	SETBP1, KIAA0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

RGS3_HUMAN
NC score	0.033737 (rank : 257)	θ value	2.36792 (rank : 212)
Query Neighborhood Hits	406	Target Neighborhood Hits	1375	Shared Neighborhood Hits	98
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

ALMS1_HUMAN
NC score	0.033611 (rank : 258)	θ value	0.21417 (rank : 93)
Query Neighborhood Hits	406	Target Neighborhood Hits	356	Shared Neighborhood Hits	55
SwissProt Accessions	Q8TCU4, Q53S05, Q580Q8, Q86VP9, Q9Y4G4	Gene names	ALMS1, KIAA0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1.

SYNJ1_MOUSE
NC score	0.033193 (rank : 259)	θ value	4.03905 (rank : 277)
Query Neighborhood Hits	406	Target Neighborhood Hits	516	Shared Neighborhood Hits	71
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

SYTL5_MOUSE
NC score	0.032646 (rank : 260)	θ value	4.03905 (rank : 278)
Query Neighborhood Hits	406	Target Neighborhood Hits	154	Shared Neighborhood Hits	15
SwissProt Accessions	Q80T23, Q812E5	Gene names	Sytl5, Slp5
Domain Architecture
Description	Synaptotagmin-like protein 5.

CCD82_MOUSE
NC score	0.032236 (rank : 261)	θ value	4.03905 (rank : 257)
Query Neighborhood Hits	406	Target Neighborhood Hits	75	Shared Neighborhood Hits	15
SwissProt Accessions	Q6PG04, Q3V462	Gene names	Ccdc82
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 82.

HRX_HUMAN
NC score	0.032144 (rank : 262)	θ value	8.99809 (rank : 376)
Query Neighborhood Hits	406	Target Neighborhood Hits	825	Shared Neighborhood Hits	104
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

SYNJ1_HUMAN
NC score	0.032120 (rank : 263)	θ value	6.88961 (rank : 354)
Query Neighborhood Hits	406	Target Neighborhood Hits	498	Shared Neighborhood Hits	69
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

CEP35_HUMAN
NC score	0.032010 (rank : 264)	θ value	1.81305 (rank : 174)
Query Neighborhood Hits	406	Target Neighborhood Hits	811	Shared Neighborhood Hits	73
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

RAI1_HUMAN
NC score	0.031635 (rank : 265)	θ value	0.365318 (rank : 117)
Query Neighborhood Hits	406	Target Neighborhood Hits	360	Shared Neighborhood Hits	41
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

K1802_MOUSE
NC score	0.031530 (rank : 266)	θ value	0.125558 (rank : 82)
Query Neighborhood Hits	406	Target Neighborhood Hits	1596	Shared Neighborhood Hits	104
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

TDRD5_HUMAN
NC score	0.031472 (rank : 267)	θ value	1.38821 (rank : 171)
Query Neighborhood Hits	406	Target Neighborhood Hits	65	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NAT2, Q5VTV0	Gene names	TDRD5
Domain Architecture
Description	Tudor domain-containing protein 5.

CFDP1_HUMAN
NC score	0.030897 (rank : 268)	θ value	5.27518 (rank : 289)
Query Neighborhood Hits	406	Target Neighborhood Hits	80	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UEE9, O00393, O00404, Q9UEF0, Q9UEF1, Q9UEF8	Gene names	CFDP1, BCNT
Domain Architecture	No domain graphic available
Description	Craniofacial development protein 1 (Bucentaur).

ZC11A_MOUSE
NC score	0.030712 (rank : 269)	θ value	1.81305 (rank : 195)
Query Neighborhood Hits	406	Target Neighborhood Hits	216	Shared Neighborhood Hits	29
SwissProt Accessions	Q6NZF1, Q6NXW9, Q6PDR6, Q80TU7, Q8C5L5, Q99JN6	Gene names	Zc3h11a, Kiaa0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

MAGC1_HUMAN
NC score	0.030669 (rank : 270)	θ value	0.21417 (rank : 97)
Query Neighborhood Hits	406	Target Neighborhood Hits	431	Shared Neighborhood Hits	65
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

LCP2_HUMAN
NC score	0.030584 (rank : 271)	θ value	0.365318 (rank : 113)
Query Neighborhood Hits	406	Target Neighborhood Hits	531	Shared Neighborhood Hits	53
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

THUM1_HUMAN
NC score	0.029848 (rank : 272)	θ value	2.36792 (rank : 219)
Query Neighborhood Hits	406	Target Neighborhood Hits	30	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NXG2, Q9BWC3	Gene names	THUMPD1
Domain Architecture
Description	THUMP domain-containing protein 1.

OGFR_HUMAN
NC score	0.029733 (rank : 273)	θ value	8.99809 (rank : 389)
Query Neighborhood Hits	406	Target Neighborhood Hits	1582	Shared Neighborhood Hits	113
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

TXLNB_HUMAN
NC score	0.029557 (rank : 274)	θ value	8.99809 (rank : 404)
Query Neighborhood Hits	406	Target Neighborhood Hits	912	Shared Neighborhood Hits	84
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

INCE_HUMAN
NC score	0.029395 (rank : 275)	θ value	0.47712 (rank : 122)
Query Neighborhood Hits	406	Target Neighborhood Hits	978	Shared Neighborhood Hits	84
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

K0141_MOUSE
NC score	0.029153 (rank : 276)	θ value	3.0926 (rank : 233)
Query Neighborhood Hits	406	Target Neighborhood Hits	21	Shared Neighborhood Hits	6
SwissProt Accessions	Q9DCV6, Q6A0B8	Gene names	Kiaa0141
Domain Architecture
Description	Protein KIAA0141.

NALP5_MOUSE
NC score	0.029126 (rank : 277)	θ value	0.365318 (rank : 114)
Query Neighborhood Hits	406	Target Neighborhood Hits	560	Shared Neighborhood Hits	58
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

DTX2_HUMAN
NC score	0.028474 (rank : 278)	θ value	0.813845 (rank : 141)
Query Neighborhood Hits	406	Target Neighborhood Hits	84	Shared Neighborhood Hits	14
SwissProt Accessions	Q86UW9, Q96H69, Q9H890, Q9P200	Gene names	DTX2, KIAA1528
Domain Architecture
Description	Protein deltex-2 (Deltex-2) (Deltex2) (hDTX2).

DMXL2_HUMAN
NC score	0.028362 (rank : 279)	θ value	0.0563607 (rank : 71)
Query Neighborhood Hits	406	Target Neighborhood Hits	374	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TDJ6, O94938	Gene names	DMXL2, KIAA0856
Domain Architecture	No domain graphic available
Description	Protein DmX-like 2 (Rabconnectin-3).

CIC_HUMAN
NC score	0.028010 (rank : 280)	θ value	8.99809 (rank : 368)
Query Neighborhood Hits	406	Target Neighborhood Hits	992	Shared Neighborhood Hits	91
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

SEMG1_HUMAN
NC score	0.027993 (rank : 281)	θ value	5.27518 (rank : 316)
Query Neighborhood Hits	406	Target Neighborhood Hits	200	Shared Neighborhood Hits	25
SwissProt Accessions	P04279, Q6X4I9, Q6Y809, Q6Y822, Q6Y823, Q86U64, Q96QM3	Gene names	SEMG1, SEMG
Domain Architecture
Description	Semenogelin-1 precursor (Semenogelin I) (SGI) [Contains: Alpha- inhibin-92; Alpha-inhibin-31; Seminal basic protein].

IF35_MOUSE
NC score	0.027905 (rank : 282)	θ value	3.0926 (rank : 232)
Query Neighborhood Hits	406	Target Neighborhood Hits	210	Shared Neighborhood Hits	37
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

LARP1_HUMAN
NC score	0.027697 (rank : 283)	θ value	5.27518 (rank : 302)
Query Neighborhood Hits	406	Target Neighborhood Hits	242	Shared Neighborhood Hits	32
SwissProt Accessions	Q6PKG0, O94836, Q8N4M2, Q8NB73, Q9UFD7	Gene names	LARP1, KIAA0731, LARP
Domain Architecture	No domain graphic available
Description	La-related protein 1 (La ribonucleoprotein domain family member 1).

BAZ1A_HUMAN
NC score	0.027278 (rank : 284)	θ value	3.0926 (rank : 223)
Query Neighborhood Hits	406	Target Neighborhood Hits	693	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

PA24F_HUMAN
NC score	0.027155 (rank : 285)	θ value	1.81305 (rank : 184)
Query Neighborhood Hits	406	Target Neighborhood Hits	78	Shared Neighborhood Hits	10
SwissProt Accessions	Q68DD2, Q6ZMC8	Gene names	PLA2G4F
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

RPTN_MOUSE
NC score	0.027150 (rank : 286)	θ value	1.81305 (rank : 188)
Query Neighborhood Hits	406	Target Neighborhood Hits	650	Shared Neighborhood Hits	47
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

ANLN_MOUSE
NC score	0.026851 (rank : 287)	θ value	5.27518 (rank : 286)
Query Neighborhood Hits	406	Target Neighborhood Hits	297	Shared Neighborhood Hits	25
SwissProt Accessions	Q8K298, Q8BL79, Q8BLB3, Q8K2N0, Q9CUY0	Gene names	Anln
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

LR37A_HUMAN
NC score	0.026533 (rank : 288)	θ value	3.0926 (rank : 235)
Query Neighborhood Hits	406	Target Neighborhood Hits	720	Shared Neighborhood Hits	68
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

TAF9B_HUMAN
NC score	0.026469 (rank : 289)	θ value	2.36792 (rank : 218)
Query Neighborhood Hits	406	Target Neighborhood Hits	54	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HBM6, Q9Y2S3	Gene names	TAF9B, TAF9L
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 9B (Transcription initiation factor TFIID subunit 9-like protein) (Transcription- associated factor TAFII31L) (Neuronal cell death-related protein 7) (DN-7).

K1543_MOUSE
NC score	0.026443 (rank : 290)	θ value	2.36792 (rank : 202)
Query Neighborhood Hits	406	Target Neighborhood Hits	497	Shared Neighborhood Hits	54
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

ESCO1_HUMAN
NC score	0.026283 (rank : 291)	θ value	4.03905 (rank : 261)
Query Neighborhood Hits	406	Target Neighborhood Hits	361	Shared Neighborhood Hits	49
SwissProt Accessions	Q5FWF5, Q69YG4, Q69YS3, Q6IMD7, Q8N3Z5, Q8NBG2, Q96PX7	Gene names	ESCO1, EFO1, KIAA1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1) (Establishment factor- like protein 1) (EFO1p) (hEFO1) (CTF7 homolog 1).

CN037_MOUSE
NC score	0.025981 (rank : 292)	θ value	4.03905 (rank : 259)
Query Neighborhood Hits	406	Target Neighborhood Hits	179	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BT18, Q8BFQ7, Q8R1Q5, Q9D6C5	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 homolog precursor.

ARHG3_MOUSE
NC score	0.025639 (rank : 293)	θ value	0.125558 (rank : 80)
Query Neighborhood Hits	406	Target Neighborhood Hits	85	Shared Neighborhood Hits	6
SwissProt Accessions	Q91X46, Q8CDM0, Q91VY4, Q99K14, Q9DC31	Gene names	Arhgef3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3.

NF2L3_HUMAN
NC score	0.025591 (rank : 294)	θ value	0.813845 (rank : 144)
Query Neighborhood Hits	406	Target Neighborhood Hits	150	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y4A8, Q6NUS0, Q7Z498, Q86UJ4, Q86VR5, Q9UQA4	Gene names	NFE2L3, NRF3
Domain Architecture	No domain graphic available
Description	Nuclear factor erythroid 2-related factor 3 (NF-E2-related factor 3) (NFE2-related factor 3) (Nuclear factor, erythroid derived 2, like 3).

GP112_HUMAN
NC score	0.025416 (rank : 295)	θ value	1.06291 (rank : 155)
Query Neighborhood Hits	406	Target Neighborhood Hits	441	Shared Neighborhood Hits	55
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

TMM29_HUMAN
NC score	0.025378 (rank : 296)	θ value	6.88961 (rank : 356)
Query Neighborhood Hits	406	Target Neighborhood Hits	40	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NDB6, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q9UI49	Gene names	TMEM29
Domain Architecture	No domain graphic available
Description	Transmembrane protein 29.

RBFAL_MOUSE
NC score	0.025289 (rank : 297)	θ value	3.0926 (rank : 243)
Query Neighborhood Hits	406	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P3B9	Gene names
Domain Architecture	No domain graphic available
Description	Putative ribosome-binding factor A, mitochondrial precursor.

TACT_HUMAN
NC score	0.025288 (rank : 298)	θ value	5.27518 (rank : 320)
Query Neighborhood Hits	406	Target Neighborhood Hits	100	Shared Neighborhood Hits	15
SwissProt Accessions	P40200	Gene names	CD96
Domain Architecture	No domain graphic available
Description	T-cell surface protein tactile precursor (T cell-activated increased late expression protein) (CD96 antigen).

MAVS_MOUSE
NC score	0.025096 (rank : 299)	θ value	5.27518 (rank : 304)
Query Neighborhood Hits	406	Target Neighborhood Hits	170	Shared Neighborhood Hits	36
SwissProt Accessions	Q8VCF0	Gene names	Mavs, Ips1, Visa
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif).

GAB1_HUMAN
NC score	0.025091 (rank : 300)	θ value	1.38821 (rank : 165)
Query Neighborhood Hits	406	Target Neighborhood Hits	279	Shared Neighborhood Hits	29
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

TULP4_HUMAN
NC score	0.025020 (rank : 301)	θ value	0.62314 (rank : 137)
Query Neighborhood Hits	406	Target Neighborhood Hits	426	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

MYO9B_HUMAN
NC score	0.024650 (rank : 302)	θ value	0.000786445 (rank : 41)
Query Neighborhood Hits	406	Target Neighborhood Hits	641	Shared Neighborhood Hits	66
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

TTC1_HUMAN
NC score	0.024601 (rank : 303)	θ value	1.06291 (rank : 160)
Query Neighborhood Hits	406	Target Neighborhood Hits	417	Shared Neighborhood Hits	34
SwissProt Accessions	Q99614, Q9BVT3	Gene names	TTC1, TPR1
Domain Architecture
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

F126A_MOUSE
NC score	0.024502 (rank : 304)	θ value	3.0926 (rank : 230)
Query Neighborhood Hits	406	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P9N1, Q99NC4	Gene names	Fam126a, Drctnnb1a
Domain Architecture	No domain graphic available
Description	Protein FAM126A (Down-regulated by CTNNB1 protein A).

GTSE1_MOUSE
NC score	0.024321 (rank : 305)	θ value	5.27518 (rank : 297)
Query Neighborhood Hits	406	Target Neighborhood Hits	245	Shared Neighborhood Hits	39
SwissProt Accessions	Q8R080, O89015, Q9CSG9	Gene names	Gtse1, B99
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (Gtse-1) (B99 protein).

SMRC1_MOUSE
NC score	0.024132 (rank : 306)	θ value	8.99809 (rank : 401)
Query Neighborhood Hits	406	Target Neighborhood Hits	459	Shared Neighborhood Hits	70
SwissProt Accessions	P97496, Q7TS80, Q7TT29	Gene names	Smarcc1, Baf155, Srg3
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155) (SWI3-related protein).

BPAEA_HUMAN
NC score	0.024072 (rank : 307)	θ value	0.279714 (rank : 102)
Query Neighborhood Hits	406	Target Neighborhood Hits	1369	Shared Neighborhood Hits	61
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

SMCE1_MOUSE
NC score	0.024061 (rank : 308)	θ value	5.27518 (rank : 318)
Query Neighborhood Hits	406	Target Neighborhood Hits	409	Shared Neighborhood Hits	42
SwissProt Accessions	O54941, Q8BPD9	Gene names	Smarce1, Baf57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator chromatin subfamily E member 1 (BRG1-associated factor 57).

IF4G1_HUMAN
NC score	0.023815 (rank : 309)	θ value	8.99809 (rank : 377)
Query Neighborhood Hits	406	Target Neighborhood Hits	347	Shared Neighborhood Hits	56
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

CR025_HUMAN
NC score	0.023133 (rank : 310)	θ value	8.99809 (rank : 369)
Query Neighborhood Hits	406	Target Neighborhood Hits	56	Shared Neighborhood Hits	18
SwissProt Accessions	Q96B23, Q5XG78, Q6N058, Q86TB5, Q8TCQ5	Gene names	C18orf25
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf25.

F10A4_HUMAN
NC score	0.022755 (rank : 311)	θ value	6.88961 (rank : 326)
Query Neighborhood Hits	406	Target Neighborhood Hits	249	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IZP2	Gene names	FAM10A4
Domain Architecture	No domain graphic available
Description	Protein FAM10A4.

MMRN2_HUMAN
NC score	0.022515 (rank : 312)	θ value	1.81305 (rank : 181)
Query Neighborhood Hits	406	Target Neighborhood Hits	400	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H8L6, Q6P2N2	Gene names	MMRN2, EMILIN3
Domain Architecture
Description	Multimerin-2 precursor (EMILIN-3) (Elastin microfibril interface located protein 3) (Elastin microfibril interfacer 3) (EndoGlyx-1 p125/p140 subunit).

PALM_MOUSE
NC score	0.022279 (rank : 313)	θ value	4.03905 (rank : 271)
Query Neighborhood Hits	406	Target Neighborhood Hits	228	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Z0P4, Q9Z0P3	Gene names	Palm
Domain Architecture
Description	Paralemmin.

UBP5_MOUSE
NC score	0.022210 (rank : 314)	θ value	1.81305 (rank : 193)
Query Neighborhood Hits	406	Target Neighborhood Hits	106	Shared Neighborhood Hits	11
SwissProt Accessions	P56399	Gene names	Usp5, Isot
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

PPAC3_MOUSE
NC score	0.022105 (rank : 315)	θ value	2.36792 (rank : 208)
Query Neighborhood Hits	406	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q91WB2	Gene names	Ppapdc3
Domain Architecture	No domain graphic available
Description	Probable lipid phosphate phosphatase PPAPDC3 (EC 3.1.3.-) (Phosphatidic acid phosphatase type 2 domain-containing protein 3).

PRG3_MOUSE
NC score	0.021613 (rank : 316)	θ value	2.36792 (rank : 209)
Query Neighborhood Hits	406	Target Neighborhood Hits	103	Shared Neighborhood Hits	9
SwissProt Accessions	Q9JL95, Q3SXA9	Gene names	Prg3, Mbp2
Domain Architecture	No domain graphic available
Description	Proteoglycan 3 precursor (Eosinophil major basic protein 2).

SVIL_MOUSE
NC score	0.021385 (rank : 317)	θ value	3.0926 (rank : 248)
Query Neighborhood Hits	406	Target Neighborhood Hits	439	Shared Neighborhood Hits	49
SwissProt Accessions	Q8K4L3	Gene names	Svil
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

FANCJ_HUMAN
NC score	0.021328 (rank : 318)	θ value	1.38821 (rank : 164)
Query Neighborhood Hits	406	Target Neighborhood Hits	72	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BX63, Q8NCI5	Gene names	BRIP1, BACH1, FANCJ
Domain Architecture	No domain graphic available
Description	Fanconi anemia group J protein (EC 3.6.1.-) (ATP-dependent RNA helicase BRIP1) (Protein FACJ) (BRCA1-interacting protein C-terminal helicase 1) (BRCA1-interacting protein 1) (BRCA1-associated C-terminal helicase 1).

GRIPE_MOUSE
NC score	0.021174 (rank : 319)	θ value	2.36792 (rank : 201)
Query Neighborhood Hits	406	Target Neighborhood Hits	70	Shared Neighborhood Hits	10
SwissProt Accessions	Q6GYP7, Q6GYP6, Q6ZQ28, Q8BNJ5, Q8C9G8, Q8CIW4, Q9JMC4	Gene names	Garnl1, Kiaa0884, Tulip1
Domain Architecture	No domain graphic available
Description	GTPase-activating RapGAP domain-like 1 (GAP-related-interacting partner to E12) (GRIPE) (Tuberin-like protein 1).

UBP5_HUMAN
NC score	0.021066 (rank : 320)	θ value	2.36792 (rank : 221)
Query Neighborhood Hits	406	Target Neighborhood Hits	109	Shared Neighborhood Hits	11
SwissProt Accessions	P45974, Q96J22	Gene names	USP5, ISOT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

EF2K_MOUSE
NC score	0.020985 (rank : 321)	θ value	5.27518 (rank : 294)
Query Neighborhood Hits	406	Target Neighborhood Hits	33	Shared Neighborhood Hits	9
SwissProt Accessions	O08796	Gene names	Eef2k
Domain Architecture
Description	Elongation factor 2 kinase (EC 2.7.11.20) (eEF-2 kinase) (eEF-2K) (Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase).

NU153_HUMAN
NC score	0.020788 (rank : 322)	θ value	5.27518 (rank : 310)
Query Neighborhood Hits	406	Target Neighborhood Hits	227	Shared Neighborhood Hits	30
SwissProt Accessions	P49790	Gene names	NUP153
Domain Architecture
Description	Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin).

E41L3_MOUSE
NC score	0.020748 (rank : 323)	θ value	0.21417 (rank : 95)
Query Neighborhood Hits	406	Target Neighborhood Hits	250	Shared Neighborhood Hits	35
SwissProt Accessions	Q9WV92, Q9R102	Gene names	Epb41l3, Dal1, Epb4.1l3
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1).

AZI1_HUMAN
NC score	0.020588 (rank : 324)	θ value	1.06291 (rank : 151)
Query Neighborhood Hits	406	Target Neighborhood Hits	1000	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

CR025_MOUSE
NC score	0.020584 (rank : 325)	θ value	8.99809 (rank : 370)
Query Neighborhood Hits	406	Target Neighborhood Hits	36	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BH50, Q3TQ72, Q8BU43	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf25 homolog.

ELF4_MOUSE
NC score	0.020549 (rank : 326)	θ value	1.06291 (rank : 152)
Query Neighborhood Hits	406	Target Neighborhood Hits	191	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z2U4	Gene names	Elf4, Mef
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-4 (E74-like factor 4) (Myeloid Elf-1-like factor).

RHBD3_HUMAN
NC score	0.019963 (rank : 327)	θ value	8.99809 (rank : 396)
Query Neighborhood Hits	406	Target Neighborhood Hits	15	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y3P4, Q6I9X3, Q9UGQ7	Gene names	RHBDD3, C22orf3
Domain Architecture
Description	Rhomboid domain-containing protein 3.

CUTL1_MOUSE
NC score	0.019931 (rank : 328)	θ value	0.163984 (rank : 86)
Query Neighborhood Hits	406	Target Neighborhood Hits	1620	Shared Neighborhood Hits	102
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

ZCH11_HUMAN
NC score	0.019886 (rank : 329)	θ value	6.88961 (rank : 360)
Query Neighborhood Hits	406	Target Neighborhood Hits	278	Shared Neighborhood Hits	34
SwissProt Accessions	Q5TAX3, Q12764, Q5TAX4, Q86XZ3	Gene names	ZCCHC11, KIAA0191
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 11.

NIN_MOUSE
NC score	0.019672 (rank : 330)	θ value	0.0736092 (rank : 73)
Query Neighborhood Hits	406	Target Neighborhood Hits	1376	Shared Neighborhood Hits	63
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

PF21A_HUMAN
NC score	0.019631 (rank : 331)	θ value	0.813845 (rank : 145)
Query Neighborhood Hits	406	Target Neighborhood Hits	303	Shared Neighborhood Hits	28
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

TMF1_HUMAN
NC score	0.019373 (rank : 332)	θ value	1.81305 (rank : 192)
Query Neighborhood Hits	406	Target Neighborhood Hits	987	Shared Neighborhood Hits	63
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

BPA1_MOUSE
NC score	0.019279 (rank : 333)	θ value	0.62314 (rank : 127)
Query Neighborhood Hits	406	Target Neighborhood Hits	1477	Shared Neighborhood Hits	76
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

HNF1B_HUMAN
NC score	0.019233 (rank : 334)	θ value	1.38821 (rank : 167)
Query Neighborhood Hits	406	Target Neighborhood Hits	80	Shared Neighborhood Hits	11
SwissProt Accessions	P35680	Gene names	TCF2, HNF1B
Domain Architecture
Description	Hepatocyte nuclear factor 1-beta (HNF-1beta) (HNF-1B) (Variant hepatic nuclear factor 1) (VHNF1) (Homeoprotein LFB3) (Transcription factor 2) (TCF-2).

SEPT9_HUMAN
NC score	0.019200 (rank : 335)	θ value	2.36792 (rank : 217)
Query Neighborhood Hits	406	Target Neighborhood Hits	706	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

LRBA_HUMAN
NC score	0.019015 (rank : 336)	θ value	0.47712 (rank : 123)
Query Neighborhood Hits	406	Target Neighborhood Hits	196	Shared Neighborhood Hits	19
SwissProt Accessions	P50851, Q9H2U3, Q9H2U4	Gene names	LRBA, BGL, CDC4L, LBA
Domain Architecture
Description	Lipopolysaccharide-responsive and beige-like anchor protein (CDC4-like protein) (Beige-like protein).

EF2K_HUMAN
NC score	0.018996 (rank : 337)	θ value	5.27518 (rank : 293)
Query Neighborhood Hits	406	Target Neighborhood Hits	32	Shared Neighborhood Hits	8
SwissProt Accessions	O00418	Gene names	EEF2K
Domain Architecture
Description	Elongation factor 2 kinase (EC 2.7.11.20) (eEF-2 kinase) (eEF-2K) (Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase).

PGCA_MOUSE
NC score	0.018885 (rank : 338)	θ value	3.0926 (rank : 239)
Query Neighborhood Hits	406	Target Neighborhood Hits	643	Shared Neighborhood Hits	56
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

HNF1B_MOUSE
NC score	0.018881 (rank : 339)	θ value	1.38821 (rank : 168)
Query Neighborhood Hits	406	Target Neighborhood Hits	78	Shared Neighborhood Hits	11
SwissProt Accessions	P27889, Q8R162, Q9CS26, Q9R1W1, Q9R1W2, Q9WTL5, Q9WTL6	Gene names	Tcf2, Hnf-1b, Hnf1b
Domain Architecture
Description	Hepatocyte nuclear factor 1-beta (HNF-1beta) (HNF-1B) (Variant hepatic nuclear factor 1) (VHNF1) (Homeoprotein LFB3).

F126A_HUMAN
NC score	0.018831 (rank : 340)	θ value	6.88961 (rank : 327)
Query Neighborhood Hits	406	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BYI3, Q6N010, Q75MR4, Q7LDZ4, Q96MX1, Q96NQ6	Gene names	FAM126A, DRCTNNB1A
Domain Architecture	No domain graphic available
Description	Protein FAM126A (Down-regulated by CTNNB1 protein A).

SC23B_HUMAN
NC score	0.018617 (rank : 341)	θ value	2.36792 (rank : 214)
Query Neighborhood Hits	406	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	Q15437, Q5W183, Q9BS15, Q9BSI2, Q9H1D7	Gene names	SEC23B
Domain Architecture
Description	Protein transport protein Sec23B (SEC23-related protein B).

SC23B_MOUSE
NC score	0.018567 (rank : 342)	θ value	2.36792 (rank : 215)
Query Neighborhood Hits	406	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D662, Q3U6B3, Q99K49, Q9QZ68	Gene names	Sec23b
Domain Architecture
Description	Protein transport protein Sec23B (SEC23-related protein B).

GMPR1_HUMAN
NC score	0.018418 (rank : 343)	θ value	1.81305 (rank : 177)
Query Neighborhood Hits	406	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	P36959, Q96HQ6	Gene names	GMPR, GMPR1
Domain Architecture
Description	GMP reductase 1 (EC 1.7.1.7) (Guanosine 5'-monophosphate oxidoreductase 1) (Guanosine monophosphate reductase 1).

BPAEA_MOUSE
NC score	0.018359 (rank : 344)	θ value	0.62314 (rank : 128)
Query Neighborhood Hits	406	Target Neighborhood Hits	1480	Shared Neighborhood Hits	66
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

THUM1_MOUSE
NC score	0.018357 (rank : 345)	θ value	8.99809 (rank : 403)
Query Neighborhood Hits	406	Target Neighborhood Hits	55	Shared Neighborhood Hits	9
SwissProt Accessions	Q99J36, Q3U6Y3	Gene names	Thumpd1
Domain Architecture
Description	THUMP domain-containing protein 1.

NEK8_HUMAN
NC score	0.018235 (rank : 346)	θ value	4.03905 (rank : 270)
Query Neighborhood Hits	406	Target Neighborhood Hits	872	Shared Neighborhood Hits	21
SwissProt Accessions	Q86SG6, Q2M1S6, Q8NDH1	Gene names	NEK8, JCK, NEK12A
Domain Architecture
Description	Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never in mitosis A-related kinase 8) (NimA-related protein kinase 8) (NIMA-related kinase 12a).

EHMT2_MOUSE
NC score	0.018214 (rank : 347)	θ value	3.0926 (rank : 227)
Query Neighborhood Hits	406	Target Neighborhood Hits	750	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

TPR_HUMAN
NC score	0.018030 (rank : 348)	θ value	2.36792 (rank : 220)
Query Neighborhood Hits	406	Target Neighborhood Hits	1921	Shared Neighborhood Hits	124
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

FMN2_MOUSE
NC score	0.017924 (rank : 349)	θ value	8.99809 (rank : 374)
Query Neighborhood Hits	406	Target Neighborhood Hits	349	Shared Neighborhood Hits	39
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

ESPL1_HUMAN
NC score	0.017809 (rank : 350)	θ value	4.03905 (rank : 262)
Query Neighborhood Hits	406	Target Neighborhood Hits	95	Shared Neighborhood Hits	11
SwissProt Accessions	Q14674	Gene names	ESPL1, ESP1, KIAA0165
Domain Architecture
Description	Separin (EC 3.4.22.49) (Separase) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein).

NGEF_HUMAN
NC score	0.017802 (rank : 351)	θ value	1.06291 (rank : 158)
Query Neighborhood Hits	406	Target Neighborhood Hits	166	Shared Neighborhood Hits	13
SwissProt Accessions	Q8N5V2, Q53QQ4, Q53ST7, Q6GMQ5, Q9NQD6	Gene names	NGEF
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

RNPS1_HUMAN
NC score	0.017801 (rank : 352)	θ value	8.99809 (rank : 397)
Query Neighborhood Hits	406	Target Neighborhood Hits	285	Shared Neighborhood Hits	23
SwissProt Accessions	Q15287, O75308, Q8WY42, Q9NYG3	Gene names	RNPS1, LDC2
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2).

RNPS1_MOUSE
NC score	0.017801 (rank : 353)	θ value	8.99809 (rank : 398)
Query Neighborhood Hits	406	Target Neighborhood Hits	285	Shared Neighborhood Hits	23
SwissProt Accessions	Q99M28, Q3TMJ1, Q922H8	Gene names	Rnps1
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1.

DNMBP_HUMAN
NC score	0.017601 (rank : 354)	θ value	0.813845 (rank : 140)
Query Neighborhood Hits	406	Target Neighborhood Hits	413	Shared Neighborhood Hits	27
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

PORIM_MOUSE
NC score	0.017496 (rank : 355)	θ value	8.99809 (rank : 392)
Query Neighborhood Hits	406	Target Neighborhood Hits	43	Shared Neighborhood Hits	13
SwissProt Accessions	Q91Z22, Q3T9F6, Q3TLL2, Q3U1R6, Q8CEX4	Gene names	Tmem123
Domain Architecture	No domain graphic available
Description	Porimin precursor (Transmembrane protein 123).

ATF4_MOUSE
NC score	0.017450 (rank : 356)	θ value	5.27518 (rank : 287)
Query Neighborhood Hits	406	Target Neighborhood Hits	102	Shared Neighborhood Hits	12
SwissProt Accessions	Q06507, Q61906	Gene names	Atf4
Domain Architecture	No domain graphic available
Description	Cyclic AMP-dependent transcription factor ATF-4 (C/EBP-related ATF) (C/ATF) (TAXREB67 homolog).

PHLB1_HUMAN
NC score	0.017427 (rank : 357)	θ value	3.0926 (rank : 241)
Query Neighborhood Hits	406	Target Neighborhood Hits	1038	Shared Neighborhood Hits	87
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

EAF1_MOUSE
NC score	0.016976 (rank : 358)	θ value	4.03905 (rank : 260)
Query Neighborhood Hits	406	Target Neighborhood Hits	78	Shared Neighborhood Hits	17
SwissProt Accessions	Q9D4C5	Gene names	Eaf1
Domain Architecture	No domain graphic available
Description	ELL-associated factor 1.

GOGB1_HUMAN
NC score	0.016944 (rank : 359)	θ value	1.38821 (rank : 166)
Query Neighborhood Hits	406	Target Neighborhood Hits	2297	Shared Neighborhood Hits	114
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

NEB1_HUMAN
NC score	0.016914 (rank : 360)	θ value	4.03905 (rank : 269)
Query Neighborhood Hits	406	Target Neighborhood Hits	829	Shared Neighborhood Hits	59
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

RAD18_MOUSE
NC score	0.016863 (rank : 361)	θ value	8.99809 (rank : 394)
Query Neighborhood Hits	406	Target Neighborhood Hits	230	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

AKAP4_HUMAN
NC score	0.016839 (rank : 362)	θ value	4.03905 (rank : 251)
Query Neighborhood Hits	406	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	Q5JQC9, O60904, O95246, Q5JQD1, Q5JQD2, Q5JQD3	Gene names	AKAP4, AKAP82
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 4 precursor (Protein kinase A-anchoring protein 4) (PRKA4) (A-kinase anchor protein 82 kDa) (AKAP 82) (hAKAP82) (Major sperm fibrous sheath protein) (HI).

DCR1A_HUMAN
NC score	0.016780 (rank : 363)	θ value	3.0926 (rank : 225)
Query Neighborhood Hits	406	Target Neighborhood Hits	43	Shared Neighborhood Hits	6
SwissProt Accessions	Q6PJP8, Q14701, Q6P5Y3, Q6PKL4	Gene names	DCLRE1A, KIAA0086, SNM1, SNM1A
Domain Architecture	No domain graphic available
Description	DNA cross-link repair 1A protein (hSNM1) (hSNM1A).

BNC2_HUMAN
NC score	0.016474 (rank : 364)	θ value	4.03905 (rank : 254)
Query Neighborhood Hits	406	Target Neighborhood Hits	439	Shared Neighborhood Hits	27
SwissProt Accessions	Q6ZN30, Q6T3A3, Q8NAR2, Q9H6J0, Q9NXV0	Gene names	BNC2
Domain Architecture	No domain graphic available
Description	Zinc finger protein basonuclin-2.

NCA11_MOUSE
NC score	0.016459 (rank : 365)	θ value	2.36792 (rank : 206)
Query Neighborhood Hits	406	Target Neighborhood Hits	661	Shared Neighborhood Hits	55
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

ITF2_MOUSE
NC score	0.016457 (rank : 366)	θ value	5.27518 (rank : 300)
Query Neighborhood Hits	406	Target Neighborhood Hits	154	Shared Neighborhood Hits	19
SwissProt Accessions	Q60722, Q60721, Q62211, Q64072, Q80UE8	Gene names	Tcf4, Itf2, Sef2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2) (Class A helix-loop-helix transcription factor ME2).

GRIPE_HUMAN
NC score	0.016299 (rank : 367)	θ value	6.88961 (rank : 329)
Query Neighborhood Hits	406	Target Neighborhood Hits	69	Shared Neighborhood Hits	7
SwissProt Accessions	Q6GYQ0, O94960, Q6GYP9, Q6ZT23, Q86YF3, Q86YF5, Q8ND69	Gene names	GARNL1, KIAA0884, TULIP1
Domain Architecture	No domain graphic available
Description	GTPase-activating Rap/Ran-GAP domain-like 1 (GAP-related-interacting partner to E12) (GRIPE) (Tuberin-like protein 1).

MTG8_HUMAN
NC score	0.016292 (rank : 368)	θ value	4.03905 (rank : 268)
Query Neighborhood Hits	406	Target Neighborhood Hits	87	Shared Neighborhood Hits	10
SwissProt Accessions	Q06455, Q06456, Q14873, Q16239, Q16346, Q16347, Q92479, Q9BRZ0	Gene names	RUNX1T1, AML1T1, CBFA2T1, CDR, ETO, MTG8, ZMYND2
Domain Architecture
Description	Protein CBFA2T1 (Protein MTG8) (Protein ETO) (Eight twenty one protein) (Cyclin-D-related protein) (Zinc finger MYND domain- containing protein 2).

NUPL_MOUSE
NC score	0.016229 (rank : 369)	θ value	5.27518 (rank : 311)
Query Neighborhood Hits	406	Target Neighborhood Hits	113	Shared Neighborhood Hits	16
SwissProt Accessions	Q8K2K6, O70448, Q8BQL5, Q8CDK9	Gene names	Hrb, Rip
Domain Architecture
Description	Nucleoporin-like protein RIP (HIV-1 Rev-binding protein homolog).

EP15R_MOUSE
NC score	0.015770 (rank : 370)	θ value	2.36792 (rank : 200)
Query Neighborhood Hits	406	Target Neighborhood Hits	1135	Shared Neighborhood Hits	76
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

DGKZ_HUMAN
NC score	0.015769 (rank : 371)	θ value	2.36792 (rank : 199)
Query Neighborhood Hits	406	Target Neighborhood Hits	551	Shared Neighborhood Hits	10
SwissProt Accessions	Q13574, O00542	Gene names	DGKZ, DAGK6
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

MYPT1_HUMAN
NC score	0.015723 (rank : 372)	θ value	0.21417 (rank : 98)
Query Neighborhood Hits	406	Target Neighborhood Hits	723	Shared Neighborhood Hits	50
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

PEG3_MOUSE
NC score	0.015695 (rank : 373)	θ value	0.0330416 (rank : 65)
Query Neighborhood Hits	406	Target Neighborhood Hits	1101	Shared Neighborhood Hits	76
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

MGRN1_HUMAN
NC score	0.015511 (rank : 374)	θ value	4.03905 (rank : 267)
Query Neighborhood Hits	406	Target Neighborhood Hits	192	Shared Neighborhood Hits	11
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

EP400_MOUSE
NC score	0.015404 (rank : 375)	θ value	5.27518 (rank : 295)
Query Neighborhood Hits	406	Target Neighborhood Hits	592	Shared Neighborhood Hits	68
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

NU205_HUMAN
NC score	0.015122 (rank : 376)	θ value	6.88961 (rank : 342)
Query Neighborhood Hits	406	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q92621, Q86YC1	Gene names	NUP205, C7orf14, KIAA0225
Domain Architecture	No domain graphic available
Description	Nuclear pore complex protein Nup205 (Nucleoporin Nup205) (205 kDa nucleoporin).

PACN2_MOUSE
NC score	0.015105 (rank : 377)	θ value	1.81305 (rank : 185)
Query Neighborhood Hits	406	Target Neighborhood Hits	382	Shared Neighborhood Hits	31
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

CENPR_HUMAN
NC score	0.014897 (rank : 378)	θ value	4.03905 (rank : 258)
Query Neighborhood Hits	406	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	Q13352, Q13353, Q5RJ42, Q5RJ44, Q5RJ45, Q7KYX2, Q96CD5, Q9UKB6	Gene names	ITGB3BP, CENPR, NRIF3
Domain Architecture	No domain graphic available
Description	Centromere protein R (CENP-R) (Nuclear receptor-interacting factor 3) (Integrin beta-3-binding protein) (Beta3-endonexin).

OXRP_HUMAN
NC score	0.014859 (rank : 379)	θ value	5.27518 (rank : 312)
Query Neighborhood Hits	406	Target Neighborhood Hits	544	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

PRG3_HUMAN
NC score	0.014851 (rank : 380)	θ value	6.88961 (rank : 344)
Query Neighborhood Hits	406	Target Neighborhood Hits	74	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y2Y8	Gene names	PRG3, MBPH
Domain Architecture	No domain graphic available
Description	Proteoglycan 3 precursor (Eosinophil major basic protein homolog) (Prepro-major basic protein homolog) (Prepro-MBPH).

TTC1_MOUSE
NC score	0.014789 (rank : 381)	θ value	6.88961 (rank : 358)
Query Neighborhood Hits	406	Target Neighborhood Hits	145	Shared Neighborhood Hits	11
SwissProt Accessions	Q91Z38, Q3TLM0	Gene names	Ttc1
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

MTG8_MOUSE
NC score	0.014751 (rank : 382)	θ value	5.27518 (rank : 305)
Query Neighborhood Hits	406	Target Neighborhood Hits	83	Shared Neighborhood Hits	9
SwissProt Accessions	Q61909	Gene names	Runx1t1, Cbfa2t1, Cbfa2t1h, Mtg8
Domain Architecture
Description	Protein CBFA2T1 (Protein MTG8).

NRIP1_MOUSE
NC score	0.014407 (rank : 383)	θ value	3.0926 (rank : 238)
Query Neighborhood Hits	406	Target Neighborhood Hits	110	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CBD1, Q8C3Y8, Q9Z2K2	Gene names	Nrip1
Domain Architecture	No domain graphic available
Description	Nuclear receptor-interacting protein 1 (Nuclear factor RIP140) (Receptor-interacting protein 140).

ASPP2_HUMAN
NC score	0.014204 (rank : 384)	θ value	4.03905 (rank : 253)
Query Neighborhood Hits	406	Target Neighborhood Hits	1156	Shared Neighborhood Hits	77
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

TITIN_HUMAN
NC score	0.013992 (rank : 385)	θ value	0.21417 (rank : 100)
Query Neighborhood Hits	406	Target Neighborhood Hits	2923	Shared Neighborhood Hits	150
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

CHD9_HUMAN
NC score	0.013982 (rank : 386)	θ value	2.36792 (rank : 197)
Query Neighborhood Hits	406	Target Neighborhood Hits	343	Shared Neighborhood Hits	45
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

ITF2_HUMAN
NC score	0.013696 (rank : 387)	θ value	5.27518 (rank : 299)
Query Neighborhood Hits	406	Target Neighborhood Hits	168	Shared Neighborhood Hits	18
SwissProt Accessions	P15884, Q15439, Q15440	Gene names	TCF4, ITF2, SEF2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (SL3-3 enhancer factor 2) (SEF-2).

ASTL_HUMAN
NC score	0.013675 (rank : 388)	θ value	3.0926 (rank : 222)
Query Neighborhood Hits	406	Target Neighborhood Hits	252	Shared Neighborhood Hits	25
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

WHRN_MOUSE
NC score	0.013532 (rank : 389)	θ value	3.0926 (rank : 249)
Query Neighborhood Hits	406	Target Neighborhood Hits	412	Shared Neighborhood Hits	37
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

LRC50_HUMAN
NC score	0.013376 (rank : 390)	θ value	5.27518 (rank : 303)
Query Neighborhood Hits	406	Target Neighborhood Hits	275	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NEP3, Q69YI8, Q69YJ0, Q96LP3	Gene names	LRRC50
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 50.

CHD9_MOUSE
NC score	0.013361 (rank : 391)	θ value	3.0926 (rank : 224)
Query Neighborhood Hits	406	Target Neighborhood Hits	427	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

AMOL1_MOUSE
NC score	0.013194 (rank : 392)	θ value	8.99809 (rank : 361)
Query Neighborhood Hits	406	Target Neighborhood Hits	445	Shared Neighborhood Hits	39
SwissProt Accessions	Q9D4H4, Q571F1	Gene names	Amotl1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

FGD6_HUMAN
NC score	0.013104 (rank : 393)	θ value	0.365318 (rank : 112)
Query Neighborhood Hits	406	Target Neighborhood Hits	237	Shared Neighborhood Hits	18
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

NCOA1_MOUSE
NC score	0.012999 (rank : 394)	θ value	1.06291 (rank : 156)
Query Neighborhood Hits	406	Target Neighborhood Hits	196	Shared Neighborhood Hits	17
SwissProt Accessions	P70365, P70366, Q61202, Q8CBI9	Gene names	Ncoa1, Src1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (Nuclear receptor coactivator protein 1) (mNRC-1).

RPGF6_HUMAN
NC score	0.012867 (rank : 395)	θ value	2.36792 (rank : 213)
Query Neighborhood Hits	406	Target Neighborhood Hits	266	Shared Neighborhood Hits	17
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

DBND2_MOUSE
NC score	0.012829 (rank : 396)	θ value	5.27518 (rank : 292)
Query Neighborhood Hits	406	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CRD4	Gene names	Dbndd2, D2Bwg0891e
Domain Architecture
Description	Dysbindin domain-containing protein 2.

BNC2_MOUSE
NC score	0.012775 (rank : 397)	θ value	8.99809 (rank : 364)
Query Neighborhood Hits	406	Target Neighborhood Hits	456	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BMQ3, Q6T3A4	Gene names	Bnc2
Domain Architecture	No domain graphic available
Description	Zinc finger protein basonuclin-2.

SMG5_HUMAN
NC score	0.012719 (rank : 398)	θ value	6.88961 (rank : 352)
Query Neighborhood Hits	406	Target Neighborhood Hits	180	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UPR3, Q5QJE7, Q8IXC0, Q8IY09, Q96IJ7	Gene names	SMG5, EST1B, KIAA1089
Domain Architecture	No domain graphic available
Description	Protein SMG5 (SMG-5 homolog) (EST1-like protein B) (LPTS-interacting protein) (LPTS-RP1).

MAML1_HUMAN
NC score	0.012686 (rank : 399)	θ value	8.99809 (rank : 383)
Query Neighborhood Hits	406	Target Neighborhood Hits	228	Shared Neighborhood Hits	28
SwissProt Accessions	Q92585, Q9NZ12	Gene names	MAML1, KIAA0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

PTN13_MOUSE
NC score	0.012504 (rank : 400)	θ value	0.125558 (rank : 84)
Query Neighborhood Hits	406	Target Neighborhood Hits	426	Shared Neighborhood Hits	29
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

PLVAP_HUMAN
NC score	0.012432 (rank : 401)	θ value	8.99809 (rank : 391)
Query Neighborhood Hits	406	Target Neighborhood Hits	397	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BX97, Q86VP0, Q8N8Y0, Q8ND68, Q8TER8, Q9BZD5	Gene names	PLVAP, FELS, PV1
Domain Architecture	No domain graphic available
Description	Plasmalemma vesicle-associated protein (Plasmalemma vesicle protein 1) (PV-1) (Fenestrated endothelial-linked structure protein).

JIP4_MOUSE
NC score	0.012396 (rank : 402)	θ value	6.88961 (rank : 331)
Query Neighborhood Hits	406	Target Neighborhood Hits	593	Shared Neighborhood Hits	45
SwissProt Accessions	Q58A65, Q3UH77, Q3UHF0, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2	Gene names	Spag9, Jip4, Jsap2, Kiaa0516, Mapk8ip4
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (JNK/SAPK-associated protein 2) (JSAP2).

MACF1_MOUSE
NC score	0.012394 (rank : 403)	θ value	8.99809 (rank : 382)
Query Neighborhood Hits	406	Target Neighborhood Hits	1313	Shared Neighborhood Hits	67
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

REST_MOUSE
NC score	0.011942 (rank : 404)	θ value	4.03905 (rank : 275)
Query Neighborhood Hits	406	Target Neighborhood Hits	1506	Shared Neighborhood Hits	80
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

SPTA2_HUMAN
NC score	0.011892 (rank : 405)	θ value	3.0926 (rank : 246)
Query Neighborhood Hits	406	Target Neighborhood Hits	888	Shared Neighborhood Hits	40
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

GIT1_MOUSE
NC score	0.011884 (rank : 406)	θ value	3.0926 (rank : 231)
Query Neighborhood Hits	406	Target Neighborhood Hits	341	Shared Neighborhood Hits	18
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

CCHCR_HUMAN
NC score	0.011834 (rank : 407)	θ value	5.27518 (rank : 288)
Query Neighborhood Hits	406	Target Neighborhood Hits	717	Shared Neighborhood Hits	42
SwissProt Accessions	Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2	Gene names	CCHCR1, C6orf18, HCR
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8).

PGCB_HUMAN
NC score	0.011711 (rank : 408)	θ value	3.0926 (rank : 240)
Query Neighborhood Hits	406	Target Neighborhood Hits	478	Shared Neighborhood Hits	42
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

NCOA2_MOUSE
NC score	0.011613 (rank : 409)	θ value	6.88961 (rank : 340)
Query Neighborhood Hits	406	Target Neighborhood Hits	281	Shared Neighborhood Hits	29
SwissProt Accessions	Q61026, O09001, P97759	Gene names	Ncoa2, Grip1, Tif2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1).

UACA_HUMAN
NC score	0.011532 (rank : 410)	θ value	1.06291 (rank : 161)
Query Neighborhood Hits	406	Target Neighborhood Hits	1622	Shared Neighborhood Hits	71
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

HAT1_HUMAN
NC score	0.011483 (rank : 411)	θ value	8.99809 (rank : 375)
Query Neighborhood Hits	406	Target Neighborhood Hits	44	Shared Neighborhood Hits	6
SwissProt Accessions	O14929, Q49A44, Q53QF0, Q53SU4	Gene names	HAT1
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase type B catalytic subunit (EC 2.3.1.48).

K0323_MOUSE
NC score	0.011131 (rank : 412)	θ value	8.99809 (rank : 378)
Query Neighborhood Hits	406	Target Neighborhood Hits	33	Shared Neighborhood Hits	6
SwissProt Accessions	Q80U38, Q8BGJ6, Q8C082	Gene names	Kiaa0323
Domain Architecture	No domain graphic available
Description	Protein KIAA0323.

SV2C_HUMAN
NC score	0.010860 (rank : 413)	θ value	3.0926 (rank : 247)
Query Neighborhood Hits	406	Target Neighborhood Hits	124	Shared Neighborhood Hits	11
SwissProt Accessions	Q496J9, Q496K1, Q9UPU8	Gene names	SV2C, KIAA1054
Domain Architecture	No domain graphic available
Description	Synaptic vesicle glycoprotein 2C.

BOK_MOUSE
NC score	0.010805 (rank : 414)	θ value	4.03905 (rank : 255)
Query Neighborhood Hits	406	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	O35425	Gene names	Bok, Mtd
Domain Architecture	No domain graphic available
Description	Bcl-2-related ovarian killer protein (Matador protein) (Apoptosis activator Mtd).

HIP1R_MOUSE
NC score	0.010688 (rank : 415)	θ value	4.03905 (rank : 263)
Query Neighborhood Hits	406	Target Neighborhood Hits	959	Shared Neighborhood Hits	55
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

PTPRJ_MOUSE
NC score	0.010636 (rank : 416)	θ value	0.813845 (rank : 147)
Query Neighborhood Hits	406	Target Neighborhood Hits	188	Shared Neighborhood Hits	10
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

RBNS5_HUMAN
NC score	0.010139 (rank : 417)	θ value	8.99809 (rank : 395)
Query Neighborhood Hits	406	Target Neighborhood Hits	242	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H1K0, Q3KP30, Q59EY8, Q8NAQ1	Gene names	ZFYVE20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20) (110 kDa protein).

EPN2_HUMAN
NC score	0.010126 (rank : 418)	θ value	5.27518 (rank : 296)
Query Neighborhood Hits	406	Target Neighborhood Hits	156	Shared Neighborhood Hits	19
SwissProt Accessions	O95208, O95207, Q9H7Z2, Q9UPT7	Gene names	EPN2, KIAA1065
Domain Architecture
Description	Epsin-2 (EPS-15-interacting protein 2).

CDC27_HUMAN
NC score	0.010047 (rank : 419)	θ value	8.99809 (rank : 366)
Query Neighborhood Hits	406	Target Neighborhood Hits	139	Shared Neighborhood Hits	16
SwissProt Accessions	P30260, Q16349, Q96F35	Gene names	CDC27
Domain Architecture
Description	Cell division cycle protein 27 homolog (CDC27Hs) (H-NUC).

NF2L2_HUMAN
NC score	0.009863 (rank : 420)	θ value	6.88961 (rank : 341)
Query Neighborhood Hits	406	Target Neighborhood Hits	109	Shared Neighborhood Hits	14
SwissProt Accessions	Q16236, Q96F71	Gene names	NFE2L2, NRF2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2) (HEBP1).

LAMP3_MOUSE
NC score	0.009555 (rank : 421)	θ value	5.27518 (rank : 301)
Query Neighborhood Hits	406	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q7TST5, Q8C1F6	Gene names	Lamp3
Domain Architecture	No domain graphic available
Description	Lysosome-associated membrane glycoprotein 3 precursor (LAMP-3) (Lysosomal-associated membrane protein 3) (DC-lysosome-associated membrane glycoprotein) (DC LAMP) (CD208 antigen).

TRML2_HUMAN
NC score	0.009520 (rank : 422)	θ value	6.88961 (rank : 357)
Query Neighborhood Hits	406	Target Neighborhood Hits	54	Shared Neighborhood Hits	5
SwissProt Accessions	Q5T2D2, Q8IWY0, Q9H8E9	Gene names	TREML2, C6orf76, TLT2
Domain Architecture	No domain graphic available
Description	Trem-like transcript 2 protein precursor (TLT-2) (Triggering receptor expressed on myeloid cells-like protein 2).

LPIN1_MOUSE
NC score	0.009289 (rank : 423)	θ value	6.88961 (rank : 336)
Query Neighborhood Hits	406	Target Neighborhood Hits	85	Shared Neighborhood Hits	11
SwissProt Accessions	Q91ZP3, Q9CQI2, Q9JLG6	Gene names	Lpin1, Fld
Domain Architecture
Description	Lipin-1 (Fatty liver dystrophy protein).

ASPM_MOUSE
NC score	0.009251 (rank : 424)	θ value	6.88961 (rank : 321)
Query Neighborhood Hits	406	Target Neighborhood Hits	150	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CJ27, O88482, Q8BJI8, Q8BKT4	Gene names	Aspm, Calmbp1, Sha1
Domain Architecture
Description	Abnormal spindle-like microcephaly-associated protein homolog (Calmodulin-binding protein 1) (Spindle and hydroxyurea checkpoint abnormal protein) (Calmodulin-binding protein Sha1).

ATBF1_HUMAN
NC score	0.009225 (rank : 425)	θ value	8.99809 (rank : 363)
Query Neighborhood Hits	406	Target Neighborhood Hits	1547	Shared Neighborhood Hits	101
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

CDN1B_MOUSE
NC score	0.009120 (rank : 426)	θ value	8.99809 (rank : 367)
Query Neighborhood Hits	406	Target Neighborhood Hits	25	Shared Neighborhood Hits	6
SwissProt Accessions	P46414	Gene names	Cdkn1b
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1B (Cyclin-dependent kinase inhibitor p27) (p27Kip1).

GCC2_HUMAN
NC score	0.009120 (rank : 427)	θ value	6.88961 (rank : 328)
Query Neighborhood Hits	406	Target Neighborhood Hits	1558	Shared Neighborhood Hits	75
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

GAK7_HUMAN
NC score	0.009118 (rank : 428)	θ value	1.81305 (rank : 176)
Query Neighborhood Hits	406	Target Neighborhood Hits	90	Shared Neighborhood Hits	11
SwissProt Accessions	Q96PI4, Q9QC08	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q23.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K18 Gag protein) (HERV-K110 Gag protein) (HERV-K(C1a) Gag protein) [Contains: Matrix protein].

UBP33_HUMAN
NC score	0.009083 (rank : 429)	θ value	4.03905 (rank : 280)
Query Neighborhood Hits	406	Target Neighborhood Hits	157	Shared Neighborhood Hits	15
SwissProt Accessions	Q8TEY7, Q8TEY6, Q96AV6, Q9H9F0, Q9UPQ5	Gene names	USP33, KIAA1097, VDU1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 33 (EC 3.1.2.15) (Ubiquitin thioesterase 33) (Ubiquitin-specific-processing protease 33) (Deubiquitinating enzyme 33) (VHL-interacting deubiquitinating enzyme 1).

RBP24_HUMAN
NC score	0.009035 (rank : 430)	θ value	6.88961 (rank : 346)
Query Neighborhood Hits	406	Target Neighborhood Hits	1559	Shared Neighborhood Hits	73
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

AMOL2_HUMAN
NC score	0.009027 (rank : 431)	θ value	8.99809 (rank : 362)
Query Neighborhood Hits	406	Target Neighborhood Hits	603	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Y2J4, Q53EP1, Q96F99, Q9UKB4	Gene names	AMOTL2, KIAA0989
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2 (Leman coiled-coil protein) (LCCP).

RFTN1_MOUSE
NC score	0.008625 (rank : 432)	θ value	5.27518 (rank : 314)
Query Neighborhood Hits	406	Target Neighborhood Hits	36	Shared Neighborhood Hits	5
SwissProt Accessions	Q6A0D4, Q3U654, Q3U8P6, Q80US1	Gene names	Rftn1, Kiaa0084
Domain Architecture	No domain graphic available
Description	Raftlin (Raft-linking protein).

ULE1B_MOUSE
NC score	0.008531 (rank : 433)	θ value	8.99809 (rank : 405)
Query Neighborhood Hits	406	Target Neighborhood Hits	56	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Z1F9, Q8BVX9	Gene names	Uble1b, Sae2, Uba2
Domain Architecture
Description	Ubiquitin-like 1-activating enzyme E1B (SUMO-1-activating enzyme subunit 2) (Anthracycline-associated resistance ARX).

DIAP3_MOUSE
NC score	0.008526 (rank : 434)	θ value	8.99809 (rank : 371)
Query Neighborhood Hits	406	Target Neighborhood Hits	221	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z207	Gene names	Diaph3, Diap3
Domain Architecture
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3) (mDIA2) (p134mDIA2).

HLX1_MOUSE
NC score	0.008275 (rank : 435)	θ value	1.81305 (rank : 178)
Query Neighborhood Hits	406	Target Neighborhood Hits	362	Shared Neighborhood Hits	12
SwissProt Accessions	Q61670	Gene names	Hlx1, Hlx
Domain Architecture
Description	Homeobox protein HLX1.

DNL4_HUMAN
NC score	0.008089 (rank : 436)	θ value	8.99809 (rank : 372)
Query Neighborhood Hits	406	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	P49917, Q8IY66, Q8TEU5	Gene names	LIG4
Domain Architecture
Description	DNA ligase 4 (EC 6.5.1.1) (DNA ligase IV) (Polydeoxyribonucleotide synthase [ATP] 4).

FOXJ2_MOUSE
NC score	0.007876 (rank : 437)	θ value	1.06291 (rank : 153)
Query Neighborhood Hits	406	Target Neighborhood Hits	151	Shared Neighborhood Hits	9
SwissProt Accessions	Q9ES18	Gene names	Foxj2, Fhx
Domain Architecture
Description	Forkhead box protein J2 (Fork head homologous X).

BUB1_HUMAN
NC score	0.007775 (rank : 438)	θ value	8.99809 (rank : 365)
Query Neighborhood Hits	406	Target Neighborhood Hits	543	Shared Neighborhood Hits	28
SwissProt Accessions	O43683, O43430, O43643, O60626	Gene names	BUB1, BUB1L
Domain Architecture
Description	Mitotic checkpoint serine/threonine-protein kinase BUB1 (EC 2.7.11.1) (hBUB1) (BUB1A).

FOXJ2_HUMAN
NC score	0.007661 (rank : 439)	θ value	1.81305 (rank : 175)
Query Neighborhood Hits	406	Target Neighborhood Hits	239	Shared Neighborhood Hits	16
SwissProt Accessions	Q9P0K8, Q96PS9, Q9NSN5	Gene names	FOXJ2, FHX
Domain Architecture
Description	Forkhead box protein J2 (Fork head homologous X).

PREX1_HUMAN
NC score	0.007655 (rank : 440)	θ value	8.99809 (rank : 393)
Query Neighborhood Hits	406	Target Neighborhood Hits	177	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

ANR38_MOUSE
NC score	0.007647 (rank : 441)	θ value	4.03905 (rank : 252)
Query Neighborhood Hits	406	Target Neighborhood Hits	512	Shared Neighborhood Hits	30
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

PDE4D_MOUSE
NC score	0.007638 (rank : 442)	θ value	4.03905 (rank : 273)
Query Neighborhood Hits	406	Target Neighborhood Hits	98	Shared Neighborhood Hits	16
SwissProt Accessions	Q01063, Q6TRH9, Q8C4Q7, Q8CG05	Gene names	Pde4d
Domain Architecture	No domain graphic available
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4D (EC 3.1.4.17) (DPDE3).

PAPOB_MOUSE
NC score	0.007592 (rank : 443)	θ value	4.03905 (rank : 272)
Query Neighborhood Hits	406	Target Neighborhood Hits	25	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WVP6, Q9R1R3	Gene names	Papolb, Papt, Tpap
Domain Architecture
Description	Poly(A) polymerase beta (EC 2.7.7.19) (PAP beta) (Polynucleotide adenylyltransferase beta) (Testis-specific poly(A) polymerase).

PDE4D_HUMAN
NC score	0.007530 (rank : 444)	θ value	5.27518 (rank : 313)
Query Neighborhood Hits	406	Target Neighborhood Hits	122	Shared Neighborhood Hits	21
SwissProt Accessions	Q08499, O43433, Q13549, Q13550, Q13551, Q7Z2L8, Q8IV84, Q8IVA9, Q8IVD2, Q8IVD3, Q9HCX7	Gene names	PDE4D
Domain Architecture
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4D (EC 3.1.4.17) (DPDE3) (PDE43).

CT054_MOUSE
NC score	0.007506 (rank : 445)	θ value	5.27518 (rank : 291)
Query Neighborhood Hits	406	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D6X5, Q8CE36, Q91WB9	Gene names
Domain Architecture
Description	Protein C20orf54 homolog precursor.

MAST4_HUMAN
NC score	0.007460 (rank : 446)	θ value	2.36792 (rank : 204)
Query Neighborhood Hits	406	Target Neighborhood Hits	1804	Shared Neighborhood Hits	103
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

STAM2_MOUSE
NC score	0.006610 (rank : 447)	θ value	6.88961 (rank : 353)
Query Neighborhood Hits	406	Target Neighborhood Hits	285	Shared Neighborhood Hits	14
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

KPB1_HUMAN
NC score	0.006526 (rank : 448)	θ value	6.88961 (rank : 332)
Query Neighborhood Hits	406	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	P46020, Q2M3D7	Gene names	PHKA1, PHKA
Domain Architecture
Description	Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform (Phosphorylase kinase alpha M subunit).

KPB1_MOUSE
NC score	0.006510 (rank : 449)	θ value	6.88961 (rank : 333)
Query Neighborhood Hits	406	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	P18826	Gene names	Phka1
Domain Architecture
Description	Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform (Phosphorylase kinase alpha M subunit).

ZN217_HUMAN
NC score	0.006457 (rank : 450)	θ value	1.06291 (rank : 162)
Query Neighborhood Hits	406	Target Neighborhood Hits	905	Shared Neighborhood Hits	44
SwissProt Accessions	O75362	Gene names	ZNF217, ZABC1
Domain Architecture	No domain graphic available
Description	Zinc finger protein 217.

PZRN3_MOUSE
NC score	0.006408 (rank : 451)	θ value	3.0926 (rank : 242)
Query Neighborhood Hits	406	Target Neighborhood Hits	447	Shared Neighborhood Hits	23
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

LYST_MOUSE
NC score	0.006125 (rank : 452)	θ value	8.99809 (rank : 381)
Query Neighborhood Hits	406	Target Neighborhood Hits	286	Shared Neighborhood Hits	10
SwissProt Accessions	P97412, Q62403, Q8VBS6	Gene names	Lyst, Bg, Chs1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige protein) (CHS1 homolog).

A2BP1_HUMAN
NC score	0.005913 (rank : 453)	θ value	4.03905 (rank : 250)
Query Neighborhood Hits	406	Target Neighborhood Hits	229	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NWB1, Q9NS20	Gene names	A2BP1, A2BP
Domain Architecture
Description	Ataxin-2-binding protein 1.

HLX1_HUMAN
NC score	0.005885 (rank : 454)	θ value	6.88961 (rank : 330)
Query Neighborhood Hits	406	Target Neighborhood Hits	370	Shared Neighborhood Hits	14
SwissProt Accessions	Q14774, Q15988	Gene names	HLX1
Domain Architecture
Description	Homeobox protein HLX1 (Homeobox protein HB24).

DCC_MOUSE
NC score	0.005859 (rank : 455)	θ value	2.36792 (rank : 198)
Query Neighborhood Hits	406	Target Neighborhood Hits	896	Shared Neighborhood Hits	51
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

ZFY1_MOUSE
NC score	0.005783 (rank : 456)	θ value	0.00665767 (rank : 48)
Query Neighborhood Hits	406	Target Neighborhood Hits	790	Shared Neighborhood Hits	31
SwissProt Accessions	P10925	Gene names	Zfy1, Zfy-1
Domain Architecture
Description	Zinc finger Y-chromosomal protein 1.

LAP4_HUMAN
NC score	0.005716 (rank : 457)	θ value	2.36792 (rank : 203)
Query Neighborhood Hits	406	Target Neighborhood Hits	608	Shared Neighborhood Hits	45
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

LAMA2_MOUSE
NC score	0.005674 (rank : 458)	θ value	3.0926 (rank : 234)
Query Neighborhood Hits	406	Target Neighborhood Hits	1198	Shared Neighborhood Hits	48
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

NFASC_MOUSE
NC score	0.005574 (rank : 459)	θ value	5.27518 (rank : 308)
Query Neighborhood Hits	406	Target Neighborhood Hits	475	Shared Neighborhood Hits	25
SwissProt Accessions	Q810U3	Gene names	Nfasc
Domain Architecture
Description	Neurofascin precursor.

PTN4_HUMAN
NC score	0.005540 (rank : 460)	θ value	6.88961 (rank : 345)
Query Neighborhood Hits	406	Target Neighborhood Hits	303	Shared Neighborhood Hits	16
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

GALT5_HUMAN
NC score	0.005508 (rank : 461)	θ value	1.06291 (rank : 154)
Query Neighborhood Hits	406	Target Neighborhood Hits	94	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z7M9, Q9UGK7, Q9UHL6	Gene names	GALNT5
Domain Architecture	No domain graphic available
Description	Polypeptide N-acetylgalactosaminyltransferase 5 (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 5) (UDP- GalNAc:polypeptide N-acetylgalactosaminyltransferase 5) (Polypeptide GalNAc transferase 5) (GalNAc-T5) (pp-GaNTase 5).

CAMKV_HUMAN
NC score	0.005438 (rank : 462)	θ value	0.62314 (rank : 129)
Query Neighborhood Hits	406	Target Neighborhood Hits	1084	Shared Neighborhood Hits	61
SwissProt Accessions	Q8NCB2, Q6FIB8, Q8NBS8, Q8NC85, Q8NDU4, Q8WTT8, Q9BQC9, Q9H0Q5	Gene names	CAMKV
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

SEM6C_HUMAN
NC score	0.005210 (rank : 463)	θ value	8.99809 (rank : 399)
Query Neighborhood Hits	406	Target Neighborhood Hits	117	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H3T2, Q5JR71, Q8WXT8, Q8WXT9, Q8WXU0, Q96JF8	Gene names	SEMA6C, KIAA1869, SEMAY
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

NFASC_HUMAN
NC score	0.005147 (rank : 464)	θ value	5.27518 (rank : 307)
Query Neighborhood Hits	406	Target Neighborhood Hits	497	Shared Neighborhood Hits	26
SwissProt Accessions	O94856, Q5T2F0, Q5T2F1, Q5T2F2, Q5T2F3, Q5T2F4, Q5T2F5, Q5T2F6, Q5T2F7, Q5T2F9, Q5T2G0, Q5W9F8, Q68DH3, Q6ZQV6, Q7Z3K1, Q96HT1, Q96K50	Gene names	NFASC, KIAA0756
Domain Architecture
Description	Neurofascin precursor.

CSTFT_MOUSE
NC score	0.005036 (rank : 465)	θ value	5.27518 (rank : 290)
Query Neighborhood Hits	406	Target Neighborhood Hits	356	Shared Neighborhood Hits	16
SwissProt Accessions	Q8C7E9, Q6A016, Q8BHH7, Q8C3W7, Q8R2Y1, Q9EPU3	Gene names	Cstf2t, Kiaa0689
Domain Architecture	No domain graphic available
Description	Cleavage stimulation factor 64 kDa subunit, tau variant (CSTF 64 kDa subunit, tau variant) (CF-1 64 kDa subunit, tau variant) (TauCstF-64).

S4A7_MOUSE
NC score	0.004541 (rank : 466)	θ value	6.88961 (rank : 348)
Query Neighborhood Hits	406	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BTY2, Q3U5H7	Gene names	Slc4a7, Nbc3
Domain Architecture	No domain graphic available
Description	Sodium bicarbonate cotransporter 3 (Solute carrier family 4 member 7).

PP2CA_HUMAN
NC score	0.004296 (rank : 467)	θ value	6.88961 (rank : 343)
Query Neighborhood Hits	406	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	P35813, O75551	Gene names	PPM1A, PPPM1A
Domain Architecture
Description	Protein phosphatase 2C isoform alpha (EC 3.1.3.16) (PP2C-alpha) (IA) (Protein phosphatase 1A).

MPIP2_HUMAN
NC score	0.004247 (rank : 468)	θ value	8.99809 (rank : 385)
Query Neighborhood Hits	406	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	P30305, O43551, Q13971, Q5JX77, Q6RSS1, Q9BRA6	Gene names	CDC25B, CDC25HU2
Domain Architecture
Description	M-phase inducer phosphatase 2 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25B).

STRN3_HUMAN
NC score	0.004093 (rank : 469)	θ value	8.99809 (rank : 402)
Query Neighborhood Hits	406	Target Neighborhood Hits	316	Shared Neighborhood Hits	12
SwissProt Accessions	Q13033, Q9NRA5	Gene names	STRN3, GS2NA, SG2NA
Domain Architecture
Description	Striatin-3 (Cell-cycle autoantigen SG2NA) (S/G2 antigen).

NEK1_MOUSE
NC score	0.003849 (rank : 470)	θ value	0.365318 (rank : 115)
Query Neighborhood Hits	406	Target Neighborhood Hits	1311	Shared Neighborhood Hits	75
SwissProt Accessions	P51954	Gene names	Nek1
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1).

SEM6A_HUMAN
NC score	0.003779 (rank : 471)	θ value	2.36792 (rank : 216)
Query Neighborhood Hits	406	Target Neighborhood Hits	96	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H2E6, Q9P2H9	Gene names	SEMA6A, KIAA1368
Domain Architecture
Description	Semaphorin-6A precursor (Semaphorin VIA) (Sema VIA) (Semaphorin 6A-1) (SEMA6A-1).

ERR1_HUMAN
NC score	0.003366 (rank : 472)	θ value	3.0926 (rank : 229)
Query Neighborhood Hits	406	Target Neighborhood Hits	157	Shared Neighborhood Hits	12
SwissProt Accessions	P11474, Q14514	Gene names	ESRRA, ERR1, ESRL1, NR3B1
Domain Architecture
Description	Steroid hormone receptor ERR1 (Estrogen-related receptor, alpha) (ERR- alpha) (Estrogen receptor-like 1).

SIP1_HUMAN
NC score	0.003350 (rank : 473)	θ value	6.88961 (rank : 350)
Query Neighborhood Hits	406	Target Neighborhood Hits	832	Shared Neighborhood Hits	50
SwissProt Accessions	O60315, Q9UED1	Gene names	ZFHX1B, KIAA0569, SIP1, ZFX1B
Domain Architecture
Description	Zinc finger homeobox protein 1b (Smad-interacting protein 1) (SMADIP1).

ZSCA5_HUMAN
NC score	0.003028 (rank : 474)	θ value	0.0113563 (rank : 52)
Query Neighborhood Hits	406	Target Neighborhood Hits	862	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BUG6	Gene names	ZSCAN5, ZNF495
Domain Architecture	No domain graphic available
Description	Zinc finger and SCAN domain-containing protein 5 (Zinc finger protein 495).

LATS2_HUMAN
NC score	0.002953 (rank : 475)	θ value	1.81305 (rank : 179)
Query Neighborhood Hits	406	Target Neighborhood Hits	884	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NRM7, Q9P2X1	Gene names	LATS2, KPM
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein) (Warts-like kinase).

SEPT1_MOUSE
NC score	0.002906 (rank : 476)	θ value	8.99809 (rank : 400)
Query Neighborhood Hits	406	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	P42209	Gene names	Sept1, Diff6, Pnutl3
Domain Architecture
Description	Septin-1 (Differentiation protein 6) (Diff6 protein).

SALL3_HUMAN
NC score	0.002849 (rank : 477)	θ value	6.88961 (rank : 349)
Query Neighborhood Hits	406	Target Neighborhood Hits	1066	Shared Neighborhood Hits	65
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

SIP1_MOUSE
NC score	0.002843 (rank : 478)	θ value	6.88961 (rank : 351)
Query Neighborhood Hits	406	Target Neighborhood Hits	870	Shared Neighborhood Hits	46
SwissProt Accessions	Q9R0G7	Gene names	Zfhx1b, Sip1, Zfx1b
Domain Architecture
Description	Zinc finger homeobox protein 1b (Smad-interacting protein 1).

LAMB1_HUMAN
NC score	0.002835 (rank : 479)	θ value	6.88961 (rank : 335)
Query Neighborhood Hits	406	Target Neighborhood Hits	1018	Shared Neighborhood Hits	40
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LATS1_HUMAN
NC score	0.002786 (rank : 480)	θ value	4.03905 (rank : 264)
Query Neighborhood Hits	406	Target Neighborhood Hits	1057	Shared Neighborhood Hits	48
SwissProt Accessions	O95835, Q6PKD0	Gene names	LATS1, WARTS
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts).

ZKSC1_HUMAN
NC score	0.002664 (rank : 481)	θ value	0.0961366 (rank : 79)
Query Neighborhood Hits	406	Target Neighborhood Hits	949	Shared Neighborhood Hits	49
SwissProt Accessions	P17029, P52745, Q8TBW5, Q8TEK7	Gene names	ZKSCAN1, KOX18, ZNF139, ZNF36
Domain Architecture	No domain graphic available
Description	Zinc finger with KRAB and SCAN domain-containing protein 1 (Zinc finger protein 36) (Zinc finger protein KOX18).

KAISO_HUMAN
NC score	0.002542 (rank : 482)	θ value	0.813845 (rank : 143)
Query Neighborhood Hits	406	Target Neighborhood Hits	840	Shared Neighborhood Hits	35
SwissProt Accessions	Q86T24, O00319, Q7Z361, Q8IVP6, Q8N3P0	Gene names	ZBTB33, KAISO, ZNF348
Domain Architecture	No domain graphic available
Description	Transcriptional regulator Kaiso (Zinc finger and BTB domain-containing protein 33).

LAMA2_HUMAN
NC score	0.002515 (rank : 483)	θ value	6.88961 (rank : 334)
Query Neighborhood Hits	406	Target Neighborhood Hits	1092	Shared Neighborhood Hits	39
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LATS1_MOUSE
NC score	0.002439 (rank : 484)	θ value	8.99809 (rank : 379)
Query Neighborhood Hits	406	Target Neighborhood Hits	1027	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BYR2, Q9Z0W4	Gene names	Lats1, Warts
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase).

LATS2_MOUSE
NC score	0.002311 (rank : 485)	θ value	1.81305 (rank : 180)
Query Neighborhood Hits	406	Target Neighborhood Hits	879	Shared Neighborhood Hits	23
SwissProt Accessions	Q7TSJ6, Q8CDJ4, Q9JMI3	Gene names	Lats2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein).

DUS7_HUMAN
NC score	0.002115 (rank : 486)	θ value	6.88961 (rank : 325)
Query Neighborhood Hits	406	Target Neighborhood Hits	69	Shared Neighborhood Hits	5
SwissProt Accessions	Q16829, Q8NFJ0	Gene names	DUSP7, PYST2
Domain Architecture
Description	Dual specificity protein phosphatase 7 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PYST2).

MGR8_HUMAN
NC score	0.002110 (rank : 487)	θ value	8.99809 (rank : 384)
Query Neighborhood Hits	406	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	O00222, O15493, O95945, O95946, Q3MIV9, Q52M02, Q6J165	Gene names	GRM8, GPRC1H, MGLUR8
Domain Architecture
Description	Metabotropic glutamate receptor 8 precursor (mGluR8).

VLDLR_HUMAN
NC score	0.001674 (rank : 488)	θ value	4.03905 (rank : 281)
Query Neighborhood Hits	406	Target Neighborhood Hits	383	Shared Neighborhood Hits	9
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

Z297B_MOUSE
NC score	0.001653 (rank : 489)	θ value	1.81305 (rank : 194)
Query Neighborhood Hits	406	Target Neighborhood Hits	806	Shared Neighborhood Hits	29
SwissProt Accessions	Q9DAI4	Gene names	Znf297b, Kiaa0414, Zfp297b
Domain Architecture
Description	Zinc finger protein 297B.

PHLPL_HUMAN
NC score	0.001395 (rank : 490)	θ value	4.03905 (rank : 274)
Query Neighborhood Hits	406	Target Neighborhood Hits	310	Shared Neighborhood Hits	8
SwissProt Accessions	Q6ZVD8, Q9NV17, Q9Y2E3	Gene names	PHLPPL, KIAA0931
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat protein phosphatase-like (EC 3.1.3.16).

PEG3_HUMAN
NC score	0.001179 (rank : 491)	θ value	8.99809 (rank : 390)
Query Neighborhood Hits	406	Target Neighborhood Hits	800	Shared Neighborhood Hits	35
SwissProt Accessions	Q9GZU2, P78418, Q5H9P9, Q7Z7H7, Q8TF75, Q9GZY2	Gene names	PEG3, KIAA0287
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein.

TMPS9_HUMAN
NC score	0.001123 (rank : 492)	θ value	4.03905 (rank : 279)
Query Neighborhood Hits	406	Target Neighborhood Hits	276	Shared Neighborhood Hits	12
SwissProt Accessions	Q7Z410, Q6ZND6, Q7Z411	Gene names	TMPRSS9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserase-I) (Polyserine protease 1) [Contains: Serase-1; Serase-2; Serase-3].

LRC33_MOUSE
NC score	0.000945 (rank : 493)	θ value	8.99809 (rank : 380)
Query Neighborhood Hits	406	Target Neighborhood Hits	296	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BMT4, Q3TIA8, Q8BTT4, Q8BUI7, Q8BY16, Q8R063	Gene names	Lrrc33
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 33 precursor.

RFWD2_MOUSE
NC score	0.000778 (rank : 494)	θ value	5.27518 (rank : 315)
Query Neighborhood Hits	406	Target Neighborhood Hits	535	Shared Neighborhood Hits	12
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

STK10_HUMAN
NC score	0.000763 (rank : 495)	θ value	5.27518 (rank : 319)
Query Neighborhood Hits	406	Target Neighborhood Hits	1921	Shared Neighborhood Hits	98
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

ZN509_MOUSE
NC score	0.000306 (rank : 496)	θ value	4.03905 (rank : 284)
Query Neighborhood Hits	406	Target Neighborhood Hits	990	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BXX2, Q8CID4, Q8K2Z6	Gene names	Znf509, Zfp509
Domain Architecture	No domain graphic available
Description	Zinc finger protein 509.

ZN628_MOUSE
NC score	-0.000063 (rank : 497)	θ value	4.03905 (rank : 285)
Query Neighborhood Hits	406	Target Neighborhood Hits	815	Shared Neighborhood Hits	30
SwissProt Accessions	Q8CJ78, Q3U2L5, Q6P5B3	Gene names	Znf628, Zec, Zfp628
Domain Architecture	No domain graphic available
Description	Zinc finger protein 628 (Zinc finger protein expressed in embryonal cells and certain adult organs).

ZBT10_HUMAN
NC score	-0.000099 (rank : 498)	θ value	6.88961 (rank : 359)
Query Neighborhood Hits	406	Target Neighborhood Hits	831	Shared Neighborhood Hits	23
SwissProt Accessions	Q96DT7, Q86W96, Q8IXI9, Q96MH9	Gene names	ZBTB10, RINZF, RINZFC
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 10 (Zinc finger protein RIN ZF).

ZN711_HUMAN
NC score	-0.000990 (rank : 499)	θ value	8.99809 (rank : 406)
Query Neighborhood Hits	406	Target Neighborhood Hits	751	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y462, Q6NX42, Q9Y4J6	Gene names	ZNF711, CMPX1, ZNF6
Domain Architecture
Description	Zinc finger protein 711 (Zinc finger protein 6).

SP1_MOUSE
NC score	-0.001207 (rank : 500)	θ value	3.0926 (rank : 245)
Query Neighborhood Hits	406	Target Neighborhood Hits	730	Shared Neighborhood Hits	28
SwissProt Accessions	O89090, O89087, Q62251, Q64167	Gene names	Sp1
Domain Architecture
Description	Transcription factor Sp1.

HUNK_HUMAN
NC score	-0.002510 (rank : 501)	θ value	5.27518 (rank : 298)
Query Neighborhood Hits	406	Target Neighborhood Hits	884	Shared Neighborhood Hits	21
SwissProt Accessions	P57058	Gene names	HUNK, MAKV
Domain Architecture
Description	Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (Serine/threonine-protein kinase MAK-V) (B19).

ENTK_MOUSE
NC score	-0.002726 (rank : 502)	θ value	8.99809 (rank : 373)
Query Neighborhood Hits	406	Target Neighborhood Hits	338	Shared Neighborhood Hits	8
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

MARK4_MOUSE
NC score	-0.002912 (rank : 503)	θ value	6.88961 (rank : 338)
Query Neighborhood Hits	406	Target Neighborhood Hits	898	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CIP4, Q80T81	Gene names	Mark4, Kiaa1860
Domain Architecture	No domain graphic available
Description	MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1).

MARK1_HUMAN
NC score	-0.003959 (rank : 504)	θ value	6.88961 (rank : 337)
Query Neighborhood Hits	406	Target Neighborhood Hits	887	Shared Neighborhood Hits	18
SwissProt Accessions	Q9P0L2, Q5VTF9, Q5VTG0, Q96SW9, Q9P251	Gene names	MARK1, KIAA1477, MARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MARK1 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 1).

YES_HUMAN
NC score	-0.004733 (rank : 505)	θ value	4.03905 (rank : 283)
Query Neighborhood Hits	406	Target Neighborhood Hits	1059	Shared Neighborhood Hits	25
SwissProt Accessions	P07947	Gene names	YES1, YES
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).