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Network neighborhood for query Sequence : CQ028_HUMAN

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CQ028_HUMAN
SwissProt Accessions	Q8IV36, Q8N5L6, Q8TE83, Q9NT34	Gene names	C17orf28, DMC1
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C17orf28 (Down-regulated in multiple cancers- 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CQ028_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	56	Target Neighborhood Hits	56	Shared Neighborhood Hits	56
SwissProt Accessions	Q8IV36, Q8N5L6, Q8TE83, Q9NT34	Gene names	C17orf28, DMC1
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C17orf28 (Down-regulated in multiple cancers- 1).

CQ028_MOUSE
θ value	0 (rank : 2)	NC score	0.985465 (rank : 2)
Query Neighborhood Hits	56	Target Neighborhood Hits	54	Shared Neighborhood Hits	29
SwissProt Accessions	Q8R1F6, Q8C8V6	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C17orf28 homolog.

DYM_MOUSE
θ value	4.1701e-05 (rank : 3)	NC score	0.260233 (rank : 3)
Query Neighborhood Hits	56	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CHY3	Gene names	Dym
Domain Architecture	No domain graphic available
Description	Dymeclin.

DYM_HUMAN
θ value	7.1131e-05 (rank : 4)	NC score	0.257747 (rank : 4)
Query Neighborhood Hits	56	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q7RTS9, Q6P2P5, Q8N2M0, Q9BVE9	Gene names	DYM
Domain Architecture	No domain graphic available
Description	Dymeclin (Dyggve-Melchior-Clausen syndrome protein).

PRG4_MOUSE
θ value	0.00298849 (rank : 5)	NC score	0.059213 (rank : 8)
Query Neighborhood Hits	56	Target Neighborhood Hits	624	Shared Neighborhood Hits	12
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

K1802_MOUSE
θ value	0.0252991 (rank : 6)	NC score	0.051393 (rank : 10)
Query Neighborhood Hits	56	Target Neighborhood Hits	1596	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

LIPA4_HUMAN
θ value	0.0252991 (rank : 7)	NC score	0.063038 (rank : 6)
Query Neighborhood Hits	56	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	O75335, O94971	Gene names	PPFIA4, KIAA0897
Domain Architecture
Description	Liprin-alpha-4 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-4) (PTPRF-interacting protein alpha-4).

BRD2_HUMAN
θ value	0.0563607 (rank : 8)	NC score	0.060900 (rank : 7)
Query Neighborhood Hits	56	Target Neighborhood Hits	242	Shared Neighborhood Hits	6
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

ENL_HUMAN
θ value	0.0961366 (rank : 9)	NC score	0.098840 (rank : 5)
Query Neighborhood Hits	56	Target Neighborhood Hits	305	Shared Neighborhood Hits	13
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

K1802_HUMAN
θ value	0.21417 (rank : 10)	NC score	0.053512 (rank : 9)
Query Neighborhood Hits	56	Target Neighborhood Hits	1378	Shared Neighborhood Hits	26
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

RECQ4_MOUSE
θ value	0.365318 (rank : 11)	NC score	0.045057 (rank : 13)
Query Neighborhood Hits	56	Target Neighborhood Hits	206	Shared Neighborhood Hits	5
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

CML2_HUMAN
θ value	0.47712 (rank : 12)	NC score	0.017647 (rank : 40)
Query Neighborhood Hits	56	Target Neighborhood Hits	724	Shared Neighborhood Hits	3
SwissProt Accessions	Q99527, O00143, O43494, Q13631, Q96F42, Q99981	Gene names	GPR30, CEPR, CMKRL2, DRY12
Domain Architecture
Description	Chemokine receptor-like 2 (G-protein coupled receptor 30) (IL8-related receptor DRY12) (Flow-induced endothelial G-protein coupled receptor) (FEG-1) (GPCR-BR).

HUWE1_MOUSE
θ value	0.62314 (rank : 13)	NC score	0.041663 (rank : 18)
Query Neighborhood Hits	56	Target Neighborhood Hits	406	Shared Neighborhood Hits	11
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

RIPK3_MOUSE
θ value	0.62314 (rank : 14)	NC score	0.015169 (rank : 44)
Query Neighborhood Hits	56	Target Neighborhood Hits	867	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QZL0	Gene names	Ripk3, Rip3
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (mRIP3).

SRRM1_HUMAN
θ value	0.813845 (rank : 15)	NC score	0.038332 (rank : 19)
Query Neighborhood Hits	56	Target Neighborhood Hits	690	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

PCD12_MOUSE
θ value	1.06291 (rank : 16)	NC score	0.013825 (rank : 46)
Query Neighborhood Hits	56	Target Neighborhood Hits	199	Shared Neighborhood Hits	5
SwissProt Accessions	O55134	Gene names	Pcdh12
Domain Architecture
Description	Protocadherin-12 precursor (Vascular cadherin-2) (Vascular endothelial cadherin-2) (VE-cadherin-2) (VE-cad-2).

THAP4_MOUSE
θ value	1.06291 (rank : 17)	NC score	0.049808 (rank : 11)
Query Neighborhood Hits	56	Target Neighborhood Hits	130	Shared Neighborhood Hits	8
SwissProt Accessions	Q6P3Z3, Q3US28, Q6NZN6, Q6PEN6, Q91WR2, Q9CVE5, Q9CVG3	Gene names	Thap4
Domain Architecture	No domain graphic available
Description	THAP domain-containing protein 4.

CM007_MOUSE
θ value	1.38821 (rank : 18)	NC score	0.026550 (rank : 31)
Query Neighborhood Hits	56	Target Neighborhood Hits	416	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

SRRM2_HUMAN
θ value	1.38821 (rank : 19)	NC score	0.036826 (rank : 22)
Query Neighborhood Hits	56	Target Neighborhood Hits	1296	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

CJ078_MOUSE
θ value	1.81305 (rank : 20)	NC score	0.044005 (rank : 15)
Query Neighborhood Hits	56	Target Neighborhood Hits	559	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

HUWE1_HUMAN
θ value	1.81305 (rank : 21)	NC score	0.038071 (rank : 20)
Query Neighborhood Hits	56	Target Neighborhood Hits	443	Shared Neighborhood Hits	11
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

REPS2_HUMAN
θ value	1.81305 (rank : 22)	NC score	0.026028 (rank : 32)
Query Neighborhood Hits	56	Target Neighborhood Hits	131	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NFH8, O43428, Q8NFI5	Gene names	REPS2, POB1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 2 (RalBP1-interacting protein 2) (Partner of RalBP1).

CHD6_HUMAN
θ value	2.36792 (rank : 23)	NC score	0.015895 (rank : 43)
Query Neighborhood Hits	56	Target Neighborhood Hits	342	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

DREB_HUMAN
θ value	2.36792 (rank : 24)	NC score	0.029325 (rank : 29)
Query Neighborhood Hits	56	Target Neighborhood Hits	450	Shared Neighborhood Hits	9
SwissProt Accessions	Q16643	Gene names	DBN1
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

LAP4_MOUSE
θ value	2.36792 (rank : 25)	NC score	0.007856 (rank : 54)
Query Neighborhood Hits	56	Target Neighborhood Hits	590	Shared Neighborhood Hits	6
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

MKL1_MOUSE
θ value	2.36792 (rank : 26)	NC score	0.022803 (rank : 36)
Query Neighborhood Hits	56	Target Neighborhood Hits	667	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

TCOF_MOUSE
θ value	2.36792 (rank : 27)	NC score	0.043463 (rank : 16)
Query Neighborhood Hits	56	Target Neighborhood Hits	471	Shared Neighborhood Hits	16
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

UBP31_HUMAN
θ value	2.36792 (rank : 28)	NC score	0.018253 (rank : 39)
Query Neighborhood Hits	56	Target Neighborhood Hits	293	Shared Neighborhood Hits	9
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

BAZ2A_MOUSE
θ value	4.03905 (rank : 29)	NC score	0.021896 (rank : 37)
Query Neighborhood Hits	56	Target Neighborhood Hits	744	Shared Neighborhood Hits	21
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

JIP2_HUMAN
θ value	4.03905 (rank : 30)	NC score	0.032145 (rank : 26)
Query Neighborhood Hits	56	Target Neighborhood Hits	288	Shared Neighborhood Hits	5
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

MAP1A_HUMAN
θ value	4.03905 (rank : 31)	NC score	0.023217 (rank : 34)
Query Neighborhood Hits	56	Target Neighborhood Hits	1626	Shared Neighborhood Hits	27
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MBB1A_MOUSE
θ value	4.03905 (rank : 32)	NC score	0.047775 (rank : 12)
Query Neighborhood Hits	56	Target Neighborhood Hits	233	Shared Neighborhood Hits	12
SwissProt Accessions	Q7TPV4, O35851, Q80Y66, Q8R4X2, Q99KP0	Gene names	Mybbp1a, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A (Myb-binding protein of 160 kDa).

NACAM_MOUSE
θ value	4.03905 (rank : 33)	NC score	0.032602 (rank : 25)
Query Neighborhood Hits	56	Target Neighborhood Hits	1866	Shared Neighborhood Hits	35
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NFAC4_HUMAN
θ value	4.03905 (rank : 34)	NC score	0.016030 (rank : 41)
Query Neighborhood Hits	56	Target Neighborhood Hits	165	Shared Neighborhood Hits	5
SwissProt Accessions	Q14934	Gene names	NFATC4, NFAT3
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 4 (NF-ATc4) (NFATc4) (T cell transcription factor NFAT3) (NF-AT3).

PAWR_HUMAN
θ value	4.03905 (rank : 35)	NC score	0.028738 (rank : 30)
Query Neighborhood Hits	56	Target Neighborhood Hits	252	Shared Neighborhood Hits	4
SwissProt Accessions	Q96IZ0, O75796, Q6FHY9, Q8N700	Gene names	PAWR, PAR4
Domain Architecture	No domain graphic available
Description	PRKC apoptosis WT1 regulator protein (Prostate apoptosis response 4 protein) (Par-4).

CDN1B_HUMAN
θ value	5.27518 (rank : 36)	NC score	0.042128 (rank : 17)
Query Neighborhood Hits	56	Target Neighborhood Hits	27	Shared Neighborhood Hits	4
SwissProt Accessions	P46527, Q16307, Q9BUS6	Gene names	CDKN1B, KIP1
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1B (Cyclin-dependent kinase inhibitor p27) (p27Kip1).

CTDP1_HUMAN
θ value	5.27518 (rank : 37)	NC score	0.030537 (rank : 28)
Query Neighborhood Hits	56	Target Neighborhood Hits	416	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

PO121_MOUSE
θ value	5.27518 (rank : 38)	NC score	0.031319 (rank : 27)
Query Neighborhood Hits	56	Target Neighborhood Hits	345	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

SRRM2_MOUSE
θ value	5.27518 (rank : 39)	NC score	0.036869 (rank : 21)
Query Neighborhood Hits	56	Target Neighborhood Hits	1470	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TROAP_HUMAN
θ value	5.27518 (rank : 40)	NC score	0.044087 (rank : 14)
Query Neighborhood Hits	56	Target Neighborhood Hits	258	Shared Neighborhood Hits	12
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

A4_MOUSE
θ value	6.88961 (rank : 41)	NC score	0.011423 (rank : 49)
Query Neighborhood Hits	56	Target Neighborhood Hits	275	Shared Neighborhood Hits	6
SwissProt Accessions	P12023, P97487, P97942, Q99K32	Gene names	App
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein homolog) (Amyloidogenic glycoprotein) (AG) [Contains: Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99 (APP-C99); Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)) (APP-C59); Gamma-CTF(57) (Gamma-secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)) (APP-C57); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

CHD9_MOUSE
θ value	6.88961 (rank : 42)	NC score	0.015946 (rank : 42)
Query Neighborhood Hits	56	Target Neighborhood Hits	427	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

DREB_MOUSE
θ value	6.88961 (rank : 43)	NC score	0.035631 (rank : 23)
Query Neighborhood Hits	56	Target Neighborhood Hits	446	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QXS6, Q922X1, Q9QXS5	Gene names	Dbn1, Drba
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

FRMD6_MOUSE
θ value	6.88961 (rank : 44)	NC score	0.010771 (rank : 50)
Query Neighborhood Hits	56	Target Neighborhood Hits	63	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C0V9, Q8BW34	Gene names	Frmd6
Domain Architecture
Description	FERM domain-containing protein 6.

IASPP_MOUSE
θ value	6.88961 (rank : 45)	NC score	0.012993 (rank : 47)
Query Neighborhood Hits	56	Target Neighborhood Hits	1024	Shared Neighborhood Hits	16
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

LATS2_HUMAN
θ value	6.88961 (rank : 46)	NC score	0.002101 (rank : 56)
Query Neighborhood Hits	56	Target Neighborhood Hits	884	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NRM7, Q9P2X1	Gene names	LATS2, KPM
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein) (Warts-like kinase).

PHF2_HUMAN
θ value	6.88961 (rank : 47)	NC score	0.023121 (rank : 35)
Query Neighborhood Hits	56	Target Neighborhood Hits	208	Shared Neighborhood Hits	9
SwissProt Accessions	O75151, Q8N3K2, Q9Y6N4	Gene names	PHF2, KIAA0662
Domain Architecture
Description	PHD finger protein 2 (GRC5).

IRAK1_HUMAN
θ value	8.99809 (rank : 48)	NC score	0.006644 (rank : 55)
Query Neighborhood Hits	56	Target Neighborhood Hits	820	Shared Neighborhood Hits	8
SwissProt Accessions	P51617, Q7Z5V4, Q96RL2	Gene names	IRAK1, IRAK
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1).

MDC1_HUMAN
θ value	8.99809 (rank : 49)	NC score	0.035377 (rank : 24)
Query Neighborhood Hits	56	Target Neighborhood Hits	1446	Shared Neighborhood Hits	32
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MYST3_HUMAN
θ value	8.99809 (rank : 50)	NC score	0.008325 (rank : 52)
Query Neighborhood Hits	56	Target Neighborhood Hits	772	Shared Neighborhood Hits	12
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

PF21B_HUMAN
θ value	8.99809 (rank : 51)	NC score	0.012349 (rank : 48)
Query Neighborhood Hits	56	Target Neighborhood Hits	197	Shared Neighborhood Hits	9
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PSD4_HUMAN
θ value	8.99809 (rank : 52)	NC score	0.010208 (rank : 51)
Query Neighborhood Hits	56	Target Neighborhood Hits	178	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NDX1, O95621, Q4ZG34, Q6GPH8, Q8IYP4	Gene names	PSD4, EFA6B, TIC
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B) (Telomeric of interleukin-1 cluster protein).

RFIP5_MOUSE
θ value	8.99809 (rank : 53)	NC score	0.015056 (rank : 45)
Query Neighborhood Hits	56	Target Neighborhood Hits	126	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R361	Gene names	Rab11fip5, D6Ertd32e, Rip11
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 5 (Rab11-FIP5) (Rab11-interacting protein Rip11).

SDC3_HUMAN
θ value	8.99809 (rank : 54)	NC score	0.019165 (rank : 38)
Query Neighborhood Hits	56	Target Neighborhood Hits	103	Shared Neighborhood Hits	7
SwissProt Accessions	O75056, Q5T1Z6, Q5T1Z7, Q96CT3, Q96PR8	Gene names	SDC3, KIAA0468
Domain Architecture
Description	Syndecan-3 (SYND3).

SSH2_HUMAN
θ value	8.99809 (rank : 55)	NC score	0.008091 (rank : 53)
Query Neighborhood Hits	56	Target Neighborhood Hits	140	Shared Neighborhood Hits	7
SwissProt Accessions	Q76I76, Q8TDB5, Q8WYL1, Q8WYL2, Q96F40, Q96H36, Q9C0D8	Gene names	SSH2, KIAA1725, SSH2L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-2L) (hSSH-2L).

TCOF_HUMAN
θ value	8.99809 (rank : 56)	NC score	0.025524 (rank : 33)
Query Neighborhood Hits	56	Target Neighborhood Hits	543	Shared Neighborhood Hits	16
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

Hits sorted by NC score

CQ028_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	56	Target Neighborhood Hits	56	Shared Neighborhood Hits	56
SwissProt Accessions	Q8IV36, Q8N5L6, Q8TE83, Q9NT34	Gene names	C17orf28, DMC1
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C17orf28 (Down-regulated in multiple cancers- 1).

CQ028_MOUSE
NC score	0.985465 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	56	Target Neighborhood Hits	54	Shared Neighborhood Hits	29
SwissProt Accessions	Q8R1F6, Q8C8V6	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C17orf28 homolog.

DYM_MOUSE
NC score	0.260233 (rank : 3)	θ value	4.1701e-05 (rank : 3)
Query Neighborhood Hits	56	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CHY3	Gene names	Dym
Domain Architecture	No domain graphic available
Description	Dymeclin.

DYM_HUMAN
NC score	0.257747 (rank : 4)	θ value	7.1131e-05 (rank : 4)
Query Neighborhood Hits	56	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q7RTS9, Q6P2P5, Q8N2M0, Q9BVE9	Gene names	DYM
Domain Architecture	No domain graphic available
Description	Dymeclin (Dyggve-Melchior-Clausen syndrome protein).

ENL_HUMAN
NC score	0.098840 (rank : 5)	θ value	0.0961366 (rank : 9)
Query Neighborhood Hits	56	Target Neighborhood Hits	305	Shared Neighborhood Hits	13
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

LIPA4_HUMAN
NC score	0.063038 (rank : 6)	θ value	0.0252991 (rank : 7)
Query Neighborhood Hits	56	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	O75335, O94971	Gene names	PPFIA4, KIAA0897
Domain Architecture
Description	Liprin-alpha-4 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-4) (PTPRF-interacting protein alpha-4).

BRD2_HUMAN
NC score	0.060900 (rank : 7)	θ value	0.0563607 (rank : 8)
Query Neighborhood Hits	56	Target Neighborhood Hits	242	Shared Neighborhood Hits	6
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

PRG4_MOUSE
NC score	0.059213 (rank : 8)	θ value	0.00298849 (rank : 5)
Query Neighborhood Hits	56	Target Neighborhood Hits	624	Shared Neighborhood Hits	12
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

K1802_HUMAN
NC score	0.053512 (rank : 9)	θ value	0.21417 (rank : 10)
Query Neighborhood Hits	56	Target Neighborhood Hits	1378	Shared Neighborhood Hits	26
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

K1802_MOUSE
NC score	0.051393 (rank : 10)	θ value	0.0252991 (rank : 6)
Query Neighborhood Hits	56	Target Neighborhood Hits	1596	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

THAP4_MOUSE
NC score	0.049808 (rank : 11)	θ value	1.06291 (rank : 17)
Query Neighborhood Hits	56	Target Neighborhood Hits	130	Shared Neighborhood Hits	8
SwissProt Accessions	Q6P3Z3, Q3US28, Q6NZN6, Q6PEN6, Q91WR2, Q9CVE5, Q9CVG3	Gene names	Thap4
Domain Architecture	No domain graphic available
Description	THAP domain-containing protein 4.

MBB1A_MOUSE
NC score	0.047775 (rank : 12)	θ value	4.03905 (rank : 32)
Query Neighborhood Hits	56	Target Neighborhood Hits	233	Shared Neighborhood Hits	12
SwissProt Accessions	Q7TPV4, O35851, Q80Y66, Q8R4X2, Q99KP0	Gene names	Mybbp1a, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A (Myb-binding protein of 160 kDa).

RECQ4_MOUSE
NC score	0.045057 (rank : 13)	θ value	0.365318 (rank : 11)
Query Neighborhood Hits	56	Target Neighborhood Hits	206	Shared Neighborhood Hits	5
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

TROAP_HUMAN
NC score	0.044087 (rank : 14)	θ value	5.27518 (rank : 40)
Query Neighborhood Hits	56	Target Neighborhood Hits	258	Shared Neighborhood Hits	12
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

CJ078_MOUSE
NC score	0.044005 (rank : 15)	θ value	1.81305 (rank : 20)
Query Neighborhood Hits	56	Target Neighborhood Hits	559	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

TCOF_MOUSE
NC score	0.043463 (rank : 16)	θ value	2.36792 (rank : 27)
Query Neighborhood Hits	56	Target Neighborhood Hits	471	Shared Neighborhood Hits	16
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

CDN1B_HUMAN
NC score	0.042128 (rank : 17)	θ value	5.27518 (rank : 36)
Query Neighborhood Hits	56	Target Neighborhood Hits	27	Shared Neighborhood Hits	4
SwissProt Accessions	P46527, Q16307, Q9BUS6	Gene names	CDKN1B, KIP1
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1B (Cyclin-dependent kinase inhibitor p27) (p27Kip1).

HUWE1_MOUSE
NC score	0.041663 (rank : 18)	θ value	0.62314 (rank : 13)
Query Neighborhood Hits	56	Target Neighborhood Hits	406	Shared Neighborhood Hits	11
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

SRRM1_HUMAN
NC score	0.038332 (rank : 19)	θ value	0.813845 (rank : 15)
Query Neighborhood Hits	56	Target Neighborhood Hits	690	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

HUWE1_HUMAN
NC score	0.038071 (rank : 20)	θ value	1.81305 (rank : 21)
Query Neighborhood Hits	56	Target Neighborhood Hits	443	Shared Neighborhood Hits	11
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

SRRM2_MOUSE
NC score	0.036869 (rank : 21)	θ value	5.27518 (rank : 39)
Query Neighborhood Hits	56	Target Neighborhood Hits	1470	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

SRRM2_HUMAN
NC score	0.036826 (rank : 22)	θ value	1.38821 (rank : 19)
Query Neighborhood Hits	56	Target Neighborhood Hits	1296	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

DREB_MOUSE
NC score	0.035631 (rank : 23)	θ value	6.88961 (rank : 43)
Query Neighborhood Hits	56	Target Neighborhood Hits	446	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QXS6, Q922X1, Q9QXS5	Gene names	Dbn1, Drba
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

MDC1_HUMAN
NC score	0.035377 (rank : 24)	θ value	8.99809 (rank : 49)
Query Neighborhood Hits	56	Target Neighborhood Hits	1446	Shared Neighborhood Hits	32
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

NACAM_MOUSE
NC score	0.032602 (rank : 25)	θ value	4.03905 (rank : 33)
Query Neighborhood Hits	56	Target Neighborhood Hits	1866	Shared Neighborhood Hits	35
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

JIP2_HUMAN
NC score	0.032145 (rank : 26)	θ value	4.03905 (rank : 30)
Query Neighborhood Hits	56	Target Neighborhood Hits	288	Shared Neighborhood Hits	5
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

PO121_MOUSE
NC score	0.031319 (rank : 27)	θ value	5.27518 (rank : 38)
Query Neighborhood Hits	56	Target Neighborhood Hits	345	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

CTDP1_HUMAN
NC score	0.030537 (rank : 28)	θ value	5.27518 (rank : 37)
Query Neighborhood Hits	56	Target Neighborhood Hits	416	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

DREB_HUMAN
NC score	0.029325 (rank : 29)	θ value	2.36792 (rank : 24)
Query Neighborhood Hits	56	Target Neighborhood Hits	450	Shared Neighborhood Hits	9
SwissProt Accessions	Q16643	Gene names	DBN1
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

PAWR_HUMAN
NC score	0.028738 (rank : 30)	θ value	4.03905 (rank : 35)
Query Neighborhood Hits	56	Target Neighborhood Hits	252	Shared Neighborhood Hits	4
SwissProt Accessions	Q96IZ0, O75796, Q6FHY9, Q8N700	Gene names	PAWR, PAR4
Domain Architecture	No domain graphic available
Description	PRKC apoptosis WT1 regulator protein (Prostate apoptosis response 4 protein) (Par-4).

CM007_MOUSE
NC score	0.026550 (rank : 31)	θ value	1.38821 (rank : 18)
Query Neighborhood Hits	56	Target Neighborhood Hits	416	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

REPS2_HUMAN
NC score	0.026028 (rank : 32)	θ value	1.81305 (rank : 22)
Query Neighborhood Hits	56	Target Neighborhood Hits	131	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NFH8, O43428, Q8NFI5	Gene names	REPS2, POB1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 2 (RalBP1-interacting protein 2) (Partner of RalBP1).

TCOF_HUMAN
NC score	0.025524 (rank : 33)	θ value	8.99809 (rank : 56)
Query Neighborhood Hits	56	Target Neighborhood Hits	543	Shared Neighborhood Hits	16
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

MAP1A_HUMAN
NC score	0.023217 (rank : 34)	θ value	4.03905 (rank : 31)
Query Neighborhood Hits	56	Target Neighborhood Hits	1626	Shared Neighborhood Hits	27
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

PHF2_HUMAN
NC score	0.023121 (rank : 35)	θ value	6.88961 (rank : 47)
Query Neighborhood Hits	56	Target Neighborhood Hits	208	Shared Neighborhood Hits	9
SwissProt Accessions	O75151, Q8N3K2, Q9Y6N4	Gene names	PHF2, KIAA0662
Domain Architecture
Description	PHD finger protein 2 (GRC5).

MKL1_MOUSE
NC score	0.022803 (rank : 36)	θ value	2.36792 (rank : 26)
Query Neighborhood Hits	56	Target Neighborhood Hits	667	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

BAZ2A_MOUSE
NC score	0.021896 (rank : 37)	θ value	4.03905 (rank : 29)
Query Neighborhood Hits	56	Target Neighborhood Hits	744	Shared Neighborhood Hits	21
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

SDC3_HUMAN
NC score	0.019165 (rank : 38)	θ value	8.99809 (rank : 54)
Query Neighborhood Hits	56	Target Neighborhood Hits	103	Shared Neighborhood Hits	7
SwissProt Accessions	O75056, Q5T1Z6, Q5T1Z7, Q96CT3, Q96PR8	Gene names	SDC3, KIAA0468
Domain Architecture
Description	Syndecan-3 (SYND3).

UBP31_HUMAN
NC score	0.018253 (rank : 39)	θ value	2.36792 (rank : 28)
Query Neighborhood Hits	56	Target Neighborhood Hits	293	Shared Neighborhood Hits	9
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

CML2_HUMAN
NC score	0.017647 (rank : 40)	θ value	0.47712 (rank : 12)
Query Neighborhood Hits	56	Target Neighborhood Hits	724	Shared Neighborhood Hits	3
SwissProt Accessions	Q99527, O00143, O43494, Q13631, Q96F42, Q99981	Gene names	GPR30, CEPR, CMKRL2, DRY12
Domain Architecture
Description	Chemokine receptor-like 2 (G-protein coupled receptor 30) (IL8-related receptor DRY12) (Flow-induced endothelial G-protein coupled receptor) (FEG-1) (GPCR-BR).

NFAC4_HUMAN
NC score	0.016030 (rank : 41)	θ value	4.03905 (rank : 34)
Query Neighborhood Hits	56	Target Neighborhood Hits	165	Shared Neighborhood Hits	5
SwissProt Accessions	Q14934	Gene names	NFATC4, NFAT3
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 4 (NF-ATc4) (NFATc4) (T cell transcription factor NFAT3) (NF-AT3).

CHD9_MOUSE
NC score	0.015946 (rank : 42)	θ value	6.88961 (rank : 42)
Query Neighborhood Hits	56	Target Neighborhood Hits	427	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

CHD6_HUMAN
NC score	0.015895 (rank : 43)	θ value	2.36792 (rank : 23)
Query Neighborhood Hits	56	Target Neighborhood Hits	342	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

RIPK3_MOUSE
NC score	0.015169 (rank : 44)	θ value	0.62314 (rank : 14)
Query Neighborhood Hits	56	Target Neighborhood Hits	867	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QZL0	Gene names	Ripk3, Rip3
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (mRIP3).

RFIP5_MOUSE
NC score	0.015056 (rank : 45)	θ value	8.99809 (rank : 53)
Query Neighborhood Hits	56	Target Neighborhood Hits	126	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R361	Gene names	Rab11fip5, D6Ertd32e, Rip11
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 5 (Rab11-FIP5) (Rab11-interacting protein Rip11).

PCD12_MOUSE
NC score	0.013825 (rank : 46)	θ value	1.06291 (rank : 16)
Query Neighborhood Hits	56	Target Neighborhood Hits	199	Shared Neighborhood Hits	5
SwissProt Accessions	O55134	Gene names	Pcdh12
Domain Architecture
Description	Protocadherin-12 precursor (Vascular cadherin-2) (Vascular endothelial cadherin-2) (VE-cadherin-2) (VE-cad-2).

IASPP_MOUSE
NC score	0.012993 (rank : 47)	θ value	6.88961 (rank : 45)
Query Neighborhood Hits	56	Target Neighborhood Hits	1024	Shared Neighborhood Hits	16
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

PF21B_HUMAN
NC score	0.012349 (rank : 48)	θ value	8.99809 (rank : 51)
Query Neighborhood Hits	56	Target Neighborhood Hits	197	Shared Neighborhood Hits	9
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

A4_MOUSE
NC score	0.011423 (rank : 49)	θ value	6.88961 (rank : 41)
Query Neighborhood Hits	56	Target Neighborhood Hits	275	Shared Neighborhood Hits	6
SwissProt Accessions	P12023, P97487, P97942, Q99K32	Gene names	App
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein homolog) (Amyloidogenic glycoprotein) (AG) [Contains: Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99 (APP-C99); Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)) (APP-C59); Gamma-CTF(57) (Gamma-secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)) (APP-C57); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

FRMD6_MOUSE
NC score	0.010771 (rank : 50)	θ value	6.88961 (rank : 44)
Query Neighborhood Hits	56	Target Neighborhood Hits	63	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C0V9, Q8BW34	Gene names	Frmd6
Domain Architecture
Description	FERM domain-containing protein 6.

PSD4_HUMAN
NC score	0.010208 (rank : 51)	θ value	8.99809 (rank : 52)
Query Neighborhood Hits	56	Target Neighborhood Hits	178	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NDX1, O95621, Q4ZG34, Q6GPH8, Q8IYP4	Gene names	PSD4, EFA6B, TIC
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B) (Telomeric of interleukin-1 cluster protein).

MYST3_HUMAN
NC score	0.008325 (rank : 52)	θ value	8.99809 (rank : 50)
Query Neighborhood Hits	56	Target Neighborhood Hits	772	Shared Neighborhood Hits	12
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

SSH2_HUMAN
NC score	0.008091 (rank : 53)	θ value	8.99809 (rank : 55)
Query Neighborhood Hits	56	Target Neighborhood Hits	140	Shared Neighborhood Hits	7
SwissProt Accessions	Q76I76, Q8TDB5, Q8WYL1, Q8WYL2, Q96F40, Q96H36, Q9C0D8	Gene names	SSH2, KIAA1725, SSH2L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-2L) (hSSH-2L).

LAP4_MOUSE
NC score	0.007856 (rank : 54)	θ value	2.36792 (rank : 25)
Query Neighborhood Hits	56	Target Neighborhood Hits	590	Shared Neighborhood Hits	6
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

IRAK1_HUMAN
NC score	0.006644 (rank : 55)	θ value	8.99809 (rank : 48)
Query Neighborhood Hits	56	Target Neighborhood Hits	820	Shared Neighborhood Hits	8
SwissProt Accessions	P51617, Q7Z5V4, Q96RL2	Gene names	IRAK1, IRAK
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1).

LATS2_HUMAN
NC score	0.002101 (rank : 56)	θ value	6.88961 (rank : 46)
Query Neighborhood Hits	56	Target Neighborhood Hits	884	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NRM7, Q9P2X1	Gene names	LATS2, KPM
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein) (Warts-like kinase).