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Network neighborhood for query Sequence : JIP2_HUMAN

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JIP2_HUMAN
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

JIP2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	288	Target Neighborhood Hits	288	Shared Neighborhood Hits	288
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

JIP2_MOUSE
θ value	0 (rank : 2)	NC score	0.941773 (rank : 2)
Query Neighborhood Hits	288	Target Neighborhood Hits	144	Shared Neighborhood Hits	99
SwissProt Accessions	Q9ERE9, Q9CXI4	Gene names	Mapk8ip2, Ib2, Jip2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

JIP1_HUMAN
θ value	1.94955e-95 (rank : 3)	NC score	0.837558 (rank : 3)
Query Neighborhood Hits	288	Target Neighborhood Hits	271	Shared Neighborhood Hits	89
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

JIP1_MOUSE
θ value	3.32542e-95 (rank : 4)	NC score	0.830408 (rank : 4)
Query Neighborhood Hits	288	Target Neighborhood Hits	259	Shared Neighborhood Hits	81
SwissProt Accessions	Q9WVI9, O35145, Q925J8, Q9R1H9, Q9R1Z1, Q9WVI7, Q9WVI8	Gene names	Mapk8ip1, Ib1, Jip1, Mapk8ip, Prkm8ip
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain-1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

NFH_MOUSE
θ value	8.11959e-09 (rank : 5)	NC score	0.088822 (rank : 71)
Query Neighborhood Hits	288	Target Neighborhood Hits	2247	Shared Neighborhood Hits	154
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

VINEX_MOUSE
θ value	0.00020696 (rank : 6)	NC score	0.247830 (rank : 6)
Query Neighborhood Hits	288	Target Neighborhood Hits	286	Shared Neighborhood Hits	67
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

VINEX_HUMAN
θ value	0.000270298 (rank : 7)	NC score	0.248224 (rank : 5)
Query Neighborhood Hits	288	Target Neighborhood Hits	270	Shared Neighborhood Hits	68
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

SRBS1_HUMAN
θ value	0.000461057 (rank : 8)	NC score	0.239997 (rank : 7)
Query Neighborhood Hits	288	Target Neighborhood Hits	396	Shared Neighborhood Hits	81
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SRBS1_MOUSE
θ value	0.000602161 (rank : 9)	NC score	0.237216 (rank : 8)
Query Neighborhood Hits	288	Target Neighborhood Hits	409	Shared Neighborhood Hits	87
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

ANKS1_HUMAN
θ value	0.00175202 (rank : 10)	NC score	0.087771 (rank : 75)
Query Neighborhood Hits	288	Target Neighborhood Hits	438	Shared Neighborhood Hits	30
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

ANKS1_MOUSE
θ value	0.00175202 (rank : 11)	NC score	0.096389 (rank : 58)
Query Neighborhood Hits	288	Target Neighborhood Hits	453	Shared Neighborhood Hits	37
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

DCC_MOUSE
θ value	0.00228821 (rank : 12)	NC score	0.042211 (rank : 333)
Query Neighborhood Hits	288	Target Neighborhood Hits	896	Shared Neighborhood Hits	53
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

ARHG5_HUMAN
θ value	0.00390308 (rank : 13)	NC score	0.168716 (rank : 12)
Query Neighborhood Hits	288	Target Neighborhood Hits	172	Shared Neighborhood Hits	52
SwissProt Accessions	Q12774	Gene names	ARHGEF5, TIM
Domain Architecture
Description	Rho guanine nucleotide exchange factor 5 (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (p60 TIM) (Transforming immortalized mammary oncogene).

GRIN1_HUMAN
θ value	0.00509761 (rank : 14)	NC score	0.108016 (rank : 40)
Query Neighborhood Hits	288	Target Neighborhood Hits	681	Shared Neighborhood Hits	84
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

RGS3_HUMAN
θ value	0.00665767 (rank : 15)	NC score	0.099321 (rank : 52)
Query Neighborhood Hits	288	Target Neighborhood Hits	1375	Shared Neighborhood Hits	133
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

STS2_HUMAN
θ value	0.00665767 (rank : 16)	NC score	0.195372 (rank : 9)
Query Neighborhood Hits	288	Target Neighborhood Hits	108	Shared Neighborhood Hits	51
SwissProt Accessions	P57075, Q6HA34, Q6HA35, Q6ISI6, Q6ISK3, Q6ISS9	Gene names	UBASH3A, STS2
Domain Architecture
Description	Suppressor of T-cell receptor signaling 2 (STS-2) (Cbl-interacting protein 4) (CLIP4) (T-cell ubiquitin ligand) (TULA).

ARHGG_MOUSE
θ value	0.00869519 (rank : 17)	NC score	0.129775 (rank : 23)
Query Neighborhood Hits	288	Target Neighborhood Hits	152	Shared Neighborhood Hits	42
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

DDEF2_HUMAN
θ value	0.0113563 (rank : 18)	NC score	0.114954 (rank : 29)
Query Neighborhood Hits	288	Target Neighborhood Hits	599	Shared Neighborhood Hits	94
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

CO039_HUMAN
θ value	0.0148317 (rank : 19)	NC score	0.099396 (rank : 51)
Query Neighborhood Hits	288	Target Neighborhood Hits	264	Shared Neighborhood Hits	42
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

OGFR_HUMAN
θ value	0.0193708 (rank : 20)	NC score	0.113882 (rank : 30)
Query Neighborhood Hits	288	Target Neighborhood Hits	1582	Shared Neighborhood Hits	155
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

BRCA1_MOUSE
θ value	0.0252991 (rank : 21)	NC score	0.057656 (rank : 240)
Query Neighborhood Hits	288	Target Neighborhood Hits	436	Shared Neighborhood Hits	12
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

DOCK1_HUMAN
θ value	0.0252991 (rank : 22)	NC score	0.092889 (rank : 63)
Query Neighborhood Hits	288	Target Neighborhood Hits	191	Shared Neighborhood Hits	52
SwissProt Accessions	Q14185	Gene names	DOCK1
Domain Architecture
Description	Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180).

DDEF2_MOUSE
θ value	0.0330416 (rank : 23)	NC score	0.112394 (rank : 33)
Query Neighborhood Hits	288	Target Neighborhood Hits	625	Shared Neighborhood Hits	90
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

LASP1_HUMAN
θ value	0.0330416 (rank : 24)	NC score	0.170665 (rank : 11)
Query Neighborhood Hits	288	Target Neighborhood Hits	293	Shared Neighborhood Hits	64
SwissProt Accessions	Q14847, Q96ED2, Q96IG0	Gene names	LASP1, MLN50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

LASP1_MOUSE
θ value	0.0330416 (rank : 25)	NC score	0.170672 (rank : 10)
Query Neighborhood Hits	288	Target Neighborhood Hits	297	Shared Neighborhood Hits	64
SwissProt Accessions	Q61792, Q62416	Gene names	Lasp1, Mln50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

TP53B_MOUSE
θ value	0.0431538 (rank : 26)	NC score	0.078422 (rank : 115)
Query Neighborhood Hits	288	Target Neighborhood Hits	644	Shared Neighborhood Hits	56
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

LEO1_MOUSE
θ value	0.0563607 (rank : 27)	NC score	0.054399 (rank : 267)
Query Neighborhood Hits	288	Target Neighborhood Hits	946	Shared Neighborhood Hits	32
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

PCLO_MOUSE
θ value	0.0736092 (rank : 28)	NC score	0.087287 (rank : 79)
Query Neighborhood Hits	288	Target Neighborhood Hits	2275	Shared Neighborhood Hits	163
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PPIP1_HUMAN
θ value	0.0736092 (rank : 29)	NC score	0.164894 (rank : 13)
Query Neighborhood Hits	288	Target Neighborhood Hits	389	Shared Neighborhood Hits	64
SwissProt Accessions	O43586, O43585, O95657	Gene names	PSTPIP1, CD2BP1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP).

RGS3_MOUSE
θ value	0.0736092 (rank : 30)	NC score	0.115661 (rank : 28)
Query Neighborhood Hits	288	Target Neighborhood Hits	1621	Shared Neighborhood Hits	151
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SF3B1_HUMAN
θ value	0.0736092 (rank : 31)	NC score	0.098198 (rank : 54)
Query Neighborhood Hits	288	Target Neighborhood Hits	341	Shared Neighborhood Hits	49
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_MOUSE
θ value	0.0736092 (rank : 32)	NC score	0.098242 (rank : 53)
Query Neighborhood Hits	288	Target Neighborhood Hits	352	Shared Neighborhood Hits	50
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SNX18_MOUSE
θ value	0.0736092 (rank : 33)	NC score	0.131622 (rank : 21)
Query Neighborhood Hits	288	Target Neighborhood Hits	198	Shared Neighborhood Hits	53
SwissProt Accessions	Q91ZR2	Gene names	Snag1, Snx18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

COIA1_HUMAN
θ value	0.0961366 (rank : 34)	NC score	0.082974 (rank : 92)
Query Neighborhood Hits	288	Target Neighborhood Hits	447	Shared Neighborhood Hits	71
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

MILK1_MOUSE
θ value	0.0961366 (rank : 35)	NC score	0.070448 (rank : 149)
Query Neighborhood Hits	288	Target Neighborhood Hits	788	Shared Neighborhood Hits	88
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

NGEF_HUMAN
θ value	0.0961366 (rank : 36)	NC score	0.112274 (rank : 34)
Query Neighborhood Hits	288	Target Neighborhood Hits	166	Shared Neighborhood Hits	41
SwissProt Accessions	Q8N5V2, Q53QQ4, Q53ST7, Q6GMQ5, Q9NQD6	Gene names	NGEF
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

SNX18_HUMAN
θ value	0.0961366 (rank : 37)	NC score	0.132035 (rank : 20)
Query Neighborhood Hits	288	Target Neighborhood Hits	207	Shared Neighborhood Hits	57
SwissProt Accessions	Q96RF0	Gene names	SNAG1, SNX18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

CABL2_MOUSE
θ value	0.125558 (rank : 38)	NC score	0.051790 (rank : 297)
Query Neighborhood Hits	288	Target Neighborhood Hits	79	Shared Neighborhood Hits	19
SwissProt Accessions	Q8K3M5	Gene names	Cables2
Domain Architecture
Description	CDK5 and ABL1 enzyme substrate 2 (Interactor with CDK3 2) (Ik3-2).

DNMBP_HUMAN
θ value	0.125558 (rank : 39)	NC score	0.138565 (rank : 17)
Query Neighborhood Hits	288	Target Neighborhood Hits	413	Shared Neighborhood Hits	69
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

INCE_HUMAN
θ value	0.125558 (rank : 40)	NC score	0.028984 (rank : 366)
Query Neighborhood Hits	288	Target Neighborhood Hits	978	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

SPN90_MOUSE
θ value	0.125558 (rank : 41)	NC score	0.107717 (rank : 41)
Query Neighborhood Hits	288	Target Neighborhood Hits	157	Shared Neighborhood Hits	35
SwissProt Accessions	Q9ESJ4, Q68G72	Gene names	Nckipsd, Spin90, Wasbp
Domain Architecture	No domain graphic available
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (N-WASP-interacting protein, 90kDa) (Wiskott-Aldrich syndrome protein-binding protein WISH) (N-WASP-binding protein).

ANK2_HUMAN
θ value	0.163984 (rank : 42)	NC score	0.049405 (rank : 313)
Query Neighborhood Hits	288	Target Neighborhood Hits	1615	Shared Neighborhood Hits	113
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

DUET_HUMAN
θ value	0.163984 (rank : 43)	NC score	0.018708 (rank : 401)
Query Neighborhood Hits	288	Target Neighborhood Hits	1220	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

TXLNB_HUMAN
θ value	0.163984 (rank : 44)	NC score	0.036914 (rank : 347)
Query Neighborhood Hits	288	Target Neighborhood Hits	912	Shared Neighborhood Hits	67
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

ZN598_HUMAN
θ value	0.163984 (rank : 45)	NC score	0.081275 (rank : 98)
Query Neighborhood Hits	288	Target Neighborhood Hits	339	Shared Neighborhood Hits	34
SwissProt Accessions	Q86UK7, Q8IW49, Q8N3D9, Q96FG3, Q9H7J3	Gene names	ZNF598
Domain Architecture	No domain graphic available
Description	Zinc finger protein 598.

DNMBP_MOUSE
θ value	0.21417 (rank : 46)	NC score	0.131432 (rank : 22)
Query Neighborhood Hits	288	Target Neighborhood Hits	435	Shared Neighborhood Hits	77
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

NGEF_MOUSE
θ value	0.21417 (rank : 47)	NC score	0.115928 (rank : 27)
Query Neighborhood Hits	288	Target Neighborhood Hits	228	Shared Neighborhood Hits	51
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

SSPO_MOUSE
θ value	0.21417 (rank : 48)	NC score	0.014738 (rank : 413)
Query Neighborhood Hits	288	Target Neighborhood Hits	800	Shared Neighborhood Hits	21
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

GAK_HUMAN
θ value	0.279714 (rank : 49)	NC score	0.018811 (rank : 400)
Query Neighborhood Hits	288	Target Neighborhood Hits	1028	Shared Neighborhood Hits	50
SwissProt Accessions	O14976, Q9BVY6	Gene names	GAK
Domain Architecture
Description	Cyclin G-associated kinase (EC 2.7.11.1).

NEBL_HUMAN
θ value	0.279714 (rank : 50)	NC score	0.136547 (rank : 18)
Query Neighborhood Hits	288	Target Neighborhood Hits	457	Shared Neighborhood Hits	71
SwissProt Accessions	O76041, Q9UIC4	Gene names	NEBL
Domain Architecture
Description	Nebulette (Actin-binding Z-disk protein).

OSTF1_HUMAN
θ value	0.279714 (rank : 51)	NC score	0.124843 (rank : 25)
Query Neighborhood Hits	288	Target Neighborhood Hits	466	Shared Neighborhood Hits	66
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

SGIP1_HUMAN
θ value	0.279714 (rank : 52)	NC score	0.076133 (rank : 123)
Query Neighborhood Hits	288	Target Neighborhood Hits	198	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

WASL_MOUSE
θ value	0.279714 (rank : 53)	NC score	0.100587 (rank : 49)
Query Neighborhood Hits	288	Target Neighborhood Hits	339	Shared Neighborhood Hits	42
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

ZN414_HUMAN
θ value	0.279714 (rank : 54)	NC score	0.035468 (rank : 352)
Query Neighborhood Hits	288	Target Neighborhood Hits	548	Shared Neighborhood Hits	15
SwissProt Accessions	Q96IQ9	Gene names	ZNF414
Domain Architecture	No domain graphic available
Description	Zinc finger protein 414.

CD2AP_HUMAN
θ value	0.365318 (rank : 55)	NC score	0.156008 (rank : 14)
Query Neighborhood Hits	288	Target Neighborhood Hits	315	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

DMN_HUMAN
θ value	0.365318 (rank : 56)	NC score	0.036577 (rank : 349)
Query Neighborhood Hits	288	Target Neighborhood Hits	690	Shared Neighborhood Hits	34
SwissProt Accessions	O15061	Gene names	DMN, KIAA0353
Domain Architecture
Description	Desmuslin.

GP153_HUMAN
θ value	0.365318 (rank : 57)	NC score	0.031075 (rank : 358)
Query Neighborhood Hits	288	Target Neighborhood Hits	332	Shared Neighborhood Hits	18
SwissProt Accessions	Q6NV75, Q5TGR5, Q6AHW8, Q86SP8	Gene names	GPR153, PGR1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 153 (G-protein coupled receptor PGR1).

MYO1F_MOUSE
θ value	0.365318 (rank : 58)	NC score	0.053194 (rank : 278)
Query Neighborhood Hits	288	Target Neighborhood Hits	262	Shared Neighborhood Hits	56
SwissProt Accessions	P70248	Gene names	Myo1f
Domain Architecture
Description	Myosin If.

PDXL2_MOUSE
θ value	0.365318 (rank : 59)	NC score	0.068804 (rank : 157)
Query Neighborhood Hits	288	Target Neighborhood Hits	213	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CAE9, Q8CFW3	Gene names	Podxl2
Domain Architecture	No domain graphic available
Description	Podocalyxin-like protein 2 precursor (Endoglycan).

SNPC2_MOUSE
θ value	0.365318 (rank : 60)	NC score	0.059132 (rank : 223)
Query Neighborhood Hits	288	Target Neighborhood Hits	83	Shared Neighborhood Hits	15
SwissProt Accessions	Q91XA5, Q3UK17, Q8CBS9	Gene names	Snapc2
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 2 (SNAPc subunit 2) (snRNA- activating protein complex 45 kDa subunit) (SNAPc 45 kDa subunit) (Small nuclear RNA-activating complex polypeptide 2).

SPEG_HUMAN
θ value	0.365318 (rank : 61)	NC score	0.030662 (rank : 360)
Query Neighborhood Hits	288	Target Neighborhood Hits	1762	Shared Neighborhood Hits	99
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

UBP42_HUMAN
θ value	0.365318 (rank : 62)	NC score	0.042809 (rank : 329)
Query Neighborhood Hits	288	Target Neighborhood Hits	445	Shared Neighborhood Hits	60
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

CN104_HUMAN
θ value	0.47712 (rank : 63)	NC score	0.062664 (rank : 199)
Query Neighborhood Hits	288	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NVR5, Q86TY8, Q969Z5	Gene names	C14orf104
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf104.

CO4A5_HUMAN
θ value	0.47712 (rank : 64)	NC score	0.063498 (rank : 188)
Query Neighborhood Hits	288	Target Neighborhood Hits	383	Shared Neighborhood Hits	61
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

CO4A6_HUMAN
θ value	0.47712 (rank : 65)	NC score	0.062695 (rank : 196)
Query Neighborhood Hits	288	Target Neighborhood Hits	318	Shared Neighborhood Hits	51
SwissProt Accessions	Q14031, Q12823, Q14053, Q5JYH6, Q9NQM5, Q9NTX3, Q9UJ76, Q9UMG6, Q9Y4L4	Gene names	COL4A6
Domain Architecture
Description	Collagen alpha-6(IV) chain precursor.

CO5A2_HUMAN
θ value	0.47712 (rank : 66)	NC score	0.072029 (rank : 145)
Query Neighborhood Hits	288	Target Neighborhood Hits	760	Shared Neighborhood Hits	89
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

OSTF1_MOUSE
θ value	0.47712 (rank : 67)	NC score	0.117899 (rank : 26)
Query Neighborhood Hits	288	Target Neighborhood Hits	467	Shared Neighborhood Hits	66
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

RIMB1_MOUSE
θ value	0.47712 (rank : 68)	NC score	0.050148 (rank : 309)
Query Neighborhood Hits	288	Target Neighborhood Hits	1376	Shared Neighborhood Hits	91
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

ACK1_HUMAN
θ value	0.62314 (rank : 69)	NC score	0.024414 (rank : 383)
Query Neighborhood Hits	288	Target Neighborhood Hits	1140	Shared Neighborhood Hits	72
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

ACK1_MOUSE
θ value	0.62314 (rank : 70)	NC score	0.023637 (rank : 385)
Query Neighborhood Hits	288	Target Neighborhood Hits	1080	Shared Neighborhood Hits	72
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

BSN_HUMAN
θ value	0.62314 (rank : 71)	NC score	0.104954 (rank : 43)
Query Neighborhood Hits	288	Target Neighborhood Hits	1537	Shared Neighborhood Hits	131
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CO3A1_MOUSE
θ value	0.62314 (rank : 72)	NC score	0.075096 (rank : 132)
Query Neighborhood Hits	288	Target Neighborhood Hits	466	Shared Neighborhood Hits	70
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

EP15_HUMAN
θ value	0.62314 (rank : 73)	NC score	0.019875 (rank : 395)
Query Neighborhood Hits	288	Target Neighborhood Hits	1021	Shared Neighborhood Hits	29
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

K1949_HUMAN
θ value	0.62314 (rank : 74)	NC score	0.052169 (rank : 290)
Query Neighborhood Hits	288	Target Neighborhood Hits	121	Shared Neighborhood Hits	16
SwissProt Accessions	Q6NYC8, Q68CK8, Q6ZUJ6, Q8NDQ4, Q8TF52, Q9BRL9	Gene names	KIAA1949
Domain Architecture	No domain graphic available
Description	Protein KIAA1949.

LPHN1_HUMAN
θ value	0.62314 (rank : 75)	NC score	0.012207 (rank : 421)
Query Neighborhood Hits	288	Target Neighborhood Hits	155	Shared Neighborhood Hits	9
SwissProt Accessions	O94910, Q96IE7, Q9BU07, Q9HAR3	Gene names	LPHN1, KIAA0821, LEC2
Domain Architecture
Description	Latrophilin-1 precursor (Calcium-independent alpha-latrotoxin receptor 1) (Lectomedin-2).

MLL2_HUMAN
θ value	0.62314 (rank : 76)	NC score	0.063913 (rank : 183)
Query Neighborhood Hits	288	Target Neighborhood Hits	1788	Shared Neighborhood Hits	126
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MYO1F_HUMAN
θ value	0.62314 (rank : 77)	NC score	0.052325 (rank : 287)
Query Neighborhood Hits	288	Target Neighborhood Hits	275	Shared Neighborhood Hits	60
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

PPIP1_MOUSE
θ value	0.62314 (rank : 78)	NC score	0.155910 (rank : 15)
Query Neighborhood Hits	288	Target Neighborhood Hits	377	Shared Neighborhood Hits	66
SwissProt Accessions	P97814, Q4V9R4	Gene names	Pstpip1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1).

SH3K1_MOUSE
θ value	0.62314 (rank : 79)	NC score	0.133629 (rank : 19)
Query Neighborhood Hits	288	Target Neighborhood Hits	332	Shared Neighborhood Hits	70
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

TTBK1_HUMAN
θ value	0.62314 (rank : 80)	NC score	0.024029 (rank : 384)
Query Neighborhood Hits	288	Target Neighborhood Hits	1058	Shared Neighborhood Hits	61
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

ARH_MOUSE
θ value	0.813845 (rank : 81)	NC score	0.108961 (rank : 38)
Query Neighborhood Hits	288	Target Neighborhood Hits	32	Shared Neighborhood Hits	7
SwissProt Accessions	Q8C142, Q6NWV6, Q8VDQ0	Gene names	Ldlrap1, Arh
Domain Architecture	No domain graphic available
Description	Low density lipoprotein receptor adapter protein 1 (Autosomal recessive hypercholesterolemia protein homolog).

COIA1_MOUSE
θ value	0.813845 (rank : 82)	NC score	0.074083 (rank : 134)
Query Neighborhood Hits	288	Target Neighborhood Hits	481	Shared Neighborhood Hits	67
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

GON4L_HUMAN
θ value	0.813845 (rank : 83)	NC score	0.045833 (rank : 322)
Query Neighborhood Hits	288	Target Neighborhood Hits	555	Shared Neighborhood Hits	46
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

GPR88_MOUSE
θ value	0.813845 (rank : 84)	NC score	0.029959 (rank : 361)
Query Neighborhood Hits	288	Target Neighborhood Hits	170	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EPB7	Gene names	Gpr88, Strg
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 88 (Striatum-specific G-protein coupled receptor).

P85A_MOUSE
θ value	0.813845 (rank : 85)	NC score	0.071082 (rank : 147)
Query Neighborhood Hits	288	Target Neighborhood Hits	435	Shared Neighborhood Hits	46
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

PRRT3_HUMAN
θ value	0.813845 (rank : 86)	NC score	0.087456 (rank : 78)
Query Neighborhood Hits	288	Target Neighborhood Hits	998	Shared Neighborhood Hits	116
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

SAPS1_HUMAN
θ value	0.813845 (rank : 87)	NC score	0.065194 (rank : 174)
Query Neighborhood Hits	288	Target Neighborhood Hits	704	Shared Neighborhood Hits	96
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

SIG12_MOUSE
θ value	0.813845 (rank : 88)	NC score	0.027877 (rank : 372)
Query Neighborhood Hits	288	Target Neighborhood Hits	225	Shared Neighborhood Hits	7
SwissProt Accessions	Q91Y57	Gene names	Siglec12, Siglec5, Siglece, Siglecl1
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 12 precursor (Siglec-12) (Sialic acid-binding Ig-like lectin-like 1) (Siglec-L1) (Sialic acid-binding Ig-like lectin 5) (Siglec-5) (mSiglec-E) (Myeloid inhibitory siglec) (MIS).

SNPC4_HUMAN
θ value	0.813845 (rank : 89)	NC score	0.073317 (rank : 139)
Query Neighborhood Hits	288	Target Neighborhood Hits	589	Shared Neighborhood Hits	92
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

APBA1_HUMAN
θ value	1.06291 (rank : 90)	NC score	0.079113 (rank : 106)
Query Neighborhood Hits	288	Target Neighborhood Hits	325	Shared Neighborhood Hits	36
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

CDT1_MOUSE
θ value	1.06291 (rank : 91)	NC score	0.051905 (rank : 295)
Query Neighborhood Hits	288	Target Neighborhood Hits	72	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R4E9, Q8BUQ1, Q8BX29, Q8R3V0, Q8R4E8	Gene names	Cdt1, Ris2
Domain Architecture	No domain graphic available
Description	DNA replication factor Cdt1 (Double parked homolog) (DUP) (Retroviral insertion site 2 protein).

CIC_HUMAN
θ value	1.06291 (rank : 92)	NC score	0.089604 (rank : 67)
Query Neighborhood Hits	288	Target Neighborhood Hits	992	Shared Neighborhood Hits	103
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CK037_HUMAN
θ value	1.06291 (rank : 93)	NC score	0.060944 (rank : 209)
Query Neighborhood Hits	288	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	Q96N53	Gene names	C11orf37
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C11orf37.

GSCR1_HUMAN
θ value	1.06291 (rank : 94)	NC score	0.094284 (rank : 62)
Query Neighborhood Hits	288	Target Neighborhood Hits	674	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

JIP3_HUMAN
θ value	1.06291 (rank : 95)	NC score	0.037826 (rank : 345)
Query Neighborhood Hits	288	Target Neighborhood Hits	1039	Shared Neighborhood Hits	76
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

K2027_HUMAN
θ value	1.06291 (rank : 96)	NC score	0.059012 (rank : 226)
Query Neighborhood Hits	288	Target Neighborhood Hits	194	Shared Neighborhood Hits	25
SwissProt Accessions	Q6ZVF9, Q8IVE4	Gene names	KIAA2027
Domain Architecture	No domain graphic available
Description	Protein KIAA2027.

PACN2_MOUSE
θ value	1.06291 (rank : 97)	NC score	0.110760 (rank : 36)
Query Neighborhood Hits	288	Target Neighborhood Hits	382	Shared Neighborhood Hits	63
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

SHAN1_HUMAN
θ value	1.06291 (rank : 98)	NC score	0.063742 (rank : 185)
Query Neighborhood Hits	288	Target Neighborhood Hits	1041	Shared Neighborhood Hits	106
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SPN90_HUMAN
θ value	1.06291 (rank : 99)	NC score	0.092037 (rank : 64)
Query Neighborhood Hits	288	Target Neighborhood Hits	157	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NZQ3, Q9UGM8	Gene names	NCKIPSD, AF3P21, SPIN90
Domain Architecture
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (AF3p21) (Diaphanous protein-interacting protein) (Dia-interacting protein 1) (DIP-1).

STAC_MOUSE
θ value	1.06291 (rank : 100)	NC score	0.107637 (rank : 42)
Query Neighborhood Hits	288	Target Neighborhood Hits	268	Shared Neighborhood Hits	53
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

ZDHC8_MOUSE
θ value	1.06291 (rank : 101)	NC score	0.027808 (rank : 373)
Query Neighborhood Hits	288	Target Neighborhood Hits	243	Shared Neighborhood Hits	44
SwissProt Accessions	Q5Y5T5, Q7TNF7	Gene names	Zdhhc8
Domain Architecture	No domain graphic available
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8).

BAZ2A_HUMAN
θ value	1.38821 (rank : 102)	NC score	0.038026 (rank : 342)
Query Neighborhood Hits	288	Target Neighborhood Hits	780	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

CO1A1_HUMAN
θ value	1.38821 (rank : 103)	NC score	0.073018 (rank : 140)
Query Neighborhood Hits	288	Target Neighborhood Hits	475	Shared Neighborhood Hits	74
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CO3A1_HUMAN
θ value	1.38821 (rank : 104)	NC score	0.072635 (rank : 142)
Query Neighborhood Hits	288	Target Neighborhood Hits	452	Shared Neighborhood Hits	72
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CQ028_MOUSE
θ value	1.38821 (rank : 105)	NC score	0.036737 (rank : 348)
Query Neighborhood Hits	288	Target Neighborhood Hits	54	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R1F6, Q8C8V6	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C17orf28 homolog.

FUT8_HUMAN
θ value	1.38821 (rank : 106)	NC score	0.104504 (rank : 46)
Query Neighborhood Hits	288	Target Neighborhood Hits	67	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BYC5, O00235, Q9BYC6, Q9P2U5, Q9P2U6	Gene names	FUT8
Domain Architecture
Description	Alpha-(1,6)-fucosyltransferase (EC 2.4.1.68) (Glycoprotein 6-alpha-L- fucosyltransferase) (GDP-fucose--glycoprotein fucosyltransferase) (GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase) (alpha1-6FucT) (Fucosyltransferase 8).

ITSN1_HUMAN
θ value	1.38821 (rank : 107)	NC score	0.081865 (rank : 96)
Query Neighborhood Hits	288	Target Neighborhood Hits	1757	Shared Neighborhood Hits	106
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

MK07_HUMAN
θ value	1.38821 (rank : 108)	NC score	0.010232 (rank : 423)
Query Neighborhood Hits	288	Target Neighborhood Hits	1087	Shared Neighborhood Hits	48
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

PACN1_HUMAN
θ value	1.38821 (rank : 109)	NC score	0.113216 (rank : 32)
Query Neighborhood Hits	288	Target Neighborhood Hits	320	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BY11, Q9P2G8	Gene names	PACSIN1, KIAA1379
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

PACN1_MOUSE
θ value	1.38821 (rank : 110)	NC score	0.113543 (rank : 31)
Query Neighborhood Hits	288	Target Neighborhood Hits	283	Shared Neighborhood Hits	60
SwissProt Accessions	Q61644	Gene names	Pacsin1, Pacsin
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

PRP1_HUMAN
θ value	1.38821 (rank : 111)	NC score	0.086466 (rank : 82)
Query Neighborhood Hits	288	Target Neighborhood Hits	385	Shared Neighborhood Hits	54
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

WASP_HUMAN
θ value	1.38821 (rank : 112)	NC score	0.069227 (rank : 156)
Query Neighborhood Hits	288	Target Neighborhood Hits	195	Shared Neighborhood Hits	37
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

YTHD1_HUMAN
θ value	1.38821 (rank : 113)	NC score	0.035558 (rank : 351)
Query Neighborhood Hits	288	Target Neighborhood Hits	71	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BYJ9, Q8N3G5, Q8TBT1, Q96AN4, Q96S57, Q9BTI7, Q9NX79	Gene names	YTHDF1, C20orf21
Domain Architecture
Description	YTH domain family protein 1 (Dermatomyositis associated with cancer putative autoantigen 1) (DACA-1).

ZN598_MOUSE
θ value	1.38821 (rank : 114)	NC score	0.052022 (rank : 293)
Query Neighborhood Hits	288	Target Neighborhood Hits	255	Shared Neighborhood Hits	14
SwissProt Accessions	Q80YR4, Q6KAT0, Q8R3S1	Gene names	Znf598, Zfp598
Domain Architecture	No domain graphic available
Description	Zinc finger protein 598.

APBA2_HUMAN
θ value	1.81305 (rank : 115)	NC score	0.061714 (rank : 202)
Query Neighborhood Hits	288	Target Neighborhood Hits	220	Shared Neighborhood Hits	16
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA2_MOUSE
θ value	1.81305 (rank : 116)	NC score	0.063679 (rank : 186)
Query Neighborhood Hits	288	Target Neighborhood Hits	219	Shared Neighborhood Hits	22
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

CC47_MOUSE
θ value	1.81305 (rank : 117)	NC score	0.027286 (rank : 374)
Query Neighborhood Hits	288	Target Neighborhood Hits	245	Shared Neighborhood Hits	12
SwissProt Accessions	Q9D024, Q3TSB5, Q3V1S7, Q8C5D9, Q920S6	Gene names	Ccdc47, Asp4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor (Adipocyte-specific protein 4).

CENG1_MOUSE
θ value	1.81305 (rank : 118)	NC score	0.040840 (rank : 336)
Query Neighborhood Hits	288	Target Neighborhood Hits	531	Shared Neighborhood Hits	39
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

CIC_MOUSE
θ value	1.81305 (rank : 119)	NC score	0.075102 (rank : 131)
Query Neighborhood Hits	288	Target Neighborhood Hits	742	Shared Neighborhood Hits	84
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

DP13A_HUMAN
θ value	1.81305 (rank : 120)	NC score	0.075231 (rank : 130)
Query Neighborhood Hits	288	Target Neighborhood Hits	107	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UKG1, Q9P2B9	Gene names	APPL1, APPL, DIP13A, KIAA1428
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 alpha (Dip13 alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1).

DP13A_MOUSE
θ value	1.81305 (rank : 121)	NC score	0.075416 (rank : 129)
Query Neighborhood Hits	288	Target Neighborhood Hits	96	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K3H0, Q3UJP7, Q69ZJ9, Q8BWZ8, Q8VCJ8, Q9CUW4	Gene names	Appl1, Dip13a, Kiaa1428
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 alpha (Dip13 alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1).

GRAP_MOUSE
θ value	1.81305 (rank : 122)	NC score	0.076158 (rank : 121)
Query Neighborhood Hits	288	Target Neighborhood Hits	309	Shared Neighborhood Hits	66
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

IQEC2_HUMAN
θ value	1.81305 (rank : 123)	NC score	0.024577 (rank : 382)
Query Neighborhood Hits	288	Target Neighborhood Hits	403	Shared Neighborhood Hits	33
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IRX5_MOUSE
θ value	1.81305 (rank : 124)	NC score	0.052283 (rank : 289)
Query Neighborhood Hits	288	Target Neighborhood Hits	324	Shared Neighborhood Hits	36
SwissProt Accessions	Q9JKQ4, Q80WV4, Q9JLL5	Gene names	Irx5, Irxb2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-5 (Iroquois homeobox protein 5) (Homeodomain protein IRXB2).

ITSN1_MOUSE
θ value	1.81305 (rank : 125)	NC score	0.082099 (rank : 94)
Query Neighborhood Hits	288	Target Neighborhood Hits	1669	Shared Neighborhood Hits	107
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

IWS1_HUMAN
θ value	1.81305 (rank : 126)	NC score	0.056700 (rank : 246)
Query Neighborhood Hits	288	Target Neighborhood Hits	1241	Shared Neighborhood Hits	73
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

NEST_HUMAN
θ value	1.81305 (rank : 127)	NC score	0.037567 (rank : 346)
Query Neighborhood Hits	288	Target Neighborhood Hits	1305	Shared Neighborhood Hits	83
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

OSBL8_HUMAN
θ value	1.81305 (rank : 128)	NC score	0.016411 (rank : 410)
Query Neighborhood Hits	288	Target Neighborhood Hits	289	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

SFPQ_HUMAN
θ value	1.81305 (rank : 129)	NC score	0.057993 (rank : 237)
Query Neighborhood Hits	288	Target Neighborhood Hits	986	Shared Neighborhood Hits	67
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

SPAG8_HUMAN
θ value	1.81305 (rank : 130)	NC score	0.060697 (rank : 211)
Query Neighborhood Hits	288	Target Neighborhood Hits	56	Shared Neighborhood Hits	11
SwissProt Accessions	Q99932, Q12937, Q5TCV8, Q8WWB4	Gene names	SPAG8
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 8 (Sperm membrane protein 1) (SMP-1) (HSD-1) (Sperm membrane protein BS-84).

BIN1_MOUSE
θ value	2.36792 (rank : 131)	NC score	0.075745 (rank : 127)
Query Neighborhood Hits	288	Target Neighborhood Hits	283	Shared Neighborhood Hits	69
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

BSN_MOUSE
θ value	2.36792 (rank : 132)	NC score	0.104608 (rank : 45)
Query Neighborhood Hits	288	Target Neighborhood Hits	2057	Shared Neighborhood Hits	157
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CAC1G_HUMAN
θ value	2.36792 (rank : 133)	NC score	0.029208 (rank : 365)
Query Neighborhood Hits	288	Target Neighborhood Hits	587	Shared Neighborhood Hits	82
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

CEND3_HUMAN
θ value	2.36792 (rank : 134)	NC score	0.029384 (rank : 363)
Query Neighborhood Hits	288	Target Neighborhood Hits	275	Shared Neighborhood Hits	25
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

CENG1_HUMAN
θ value	2.36792 (rank : 135)	NC score	0.035790 (rank : 350)
Query Neighborhood Hits	288	Target Neighborhood Hits	544	Shared Neighborhood Hits	37
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

CLIC6_HUMAN
θ value	2.36792 (rank : 136)	NC score	0.042618 (rank : 332)
Query Neighborhood Hits	288	Target Neighborhood Hits	289	Shared Neighborhood Hits	50
SwissProt Accessions	Q96NY7, Q8IX31	Gene names	CLIC6, CLIC1L
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel 6.

CO1A1_MOUSE
θ value	2.36792 (rank : 137)	NC score	0.071579 (rank : 146)
Query Neighborhood Hits	288	Target Neighborhood Hits	457	Shared Neighborhood Hits	79
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CO9A3_HUMAN
θ value	2.36792 (rank : 138)	NC score	0.062815 (rank : 192)
Query Neighborhood Hits	288	Target Neighborhood Hits	361	Shared Neighborhood Hits	64
SwissProt Accessions	Q14050, Q13681, Q9H4G9, Q9UPE2	Gene names	COL9A3
Domain Architecture	No domain graphic available
Description	Collagen alpha-3(IX) chain precursor.

COCA1_HUMAN
θ value	2.36792 (rank : 139)	NC score	0.038919 (rank : 338)
Query Neighborhood Hits	288	Target Neighborhood Hits	458	Shared Neighborhood Hits	46
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

FMN1A_MOUSE
θ value	2.36792 (rank : 140)	NC score	0.052713 (rank : 281)
Query Neighborhood Hits	288	Target Neighborhood Hits	423	Shared Neighborhood Hits	43
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

FMN1B_MOUSE
θ value	2.36792 (rank : 141)	NC score	0.054774 (rank : 264)
Query Neighborhood Hits	288	Target Neighborhood Hits	447	Shared Neighborhood Hits	42
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

FUT8_MOUSE
θ value	2.36792 (rank : 142)	NC score	0.096765 (rank : 56)
Query Neighborhood Hits	288	Target Neighborhood Hits	115	Shared Neighborhood Hits	30
SwissProt Accessions	Q9WTS2, Q921U1	Gene names	Fut8
Domain Architecture
Description	Alpha-(1,6)-fucosyltransferase (EC 2.4.1.68) (Glycoprotein 6-alpha-L- fucosyltransferase) (GDP-fucose--glycoprotein fucosyltransferase) (GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase) (alpha1-6FucT) (Fucosyltransferase 8).

MEF2B_HUMAN
θ value	2.36792 (rank : 143)	NC score	0.032041 (rank : 356)
Query Neighborhood Hits	288	Target Neighborhood Hits	150	Shared Neighborhood Hits	29
SwissProt Accessions	Q02080	Gene names	MEF2B, XMEF2
Domain Architecture
Description	Myocyte-specific enhancer factor 2B (Serum response factor-like protein 2) (XMEF2) (RSRFR2).

NASP_HUMAN
θ value	2.36792 (rank : 144)	NC score	0.049480 (rank : 312)
Query Neighborhood Hits	288	Target Neighborhood Hits	709	Shared Neighborhood Hits	32
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

NCF2_HUMAN
θ value	2.36792 (rank : 145)	NC score	0.140690 (rank : 16)
Query Neighborhood Hits	288	Target Neighborhood Hits	229	Shared Neighborhood Hits	56
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

OPHN1_MOUSE
θ value	2.36792 (rank : 146)	NC score	0.025444 (rank : 380)
Query Neighborhood Hits	288	Target Neighborhood Hits	174	Shared Neighborhood Hits	15
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

P85A_HUMAN
θ value	2.36792 (rank : 147)	NC score	0.061404 (rank : 204)
Query Neighborhood Hits	288	Target Neighborhood Hits	479	Shared Neighborhood Hits	43
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

PRGC2_MOUSE
θ value	2.36792 (rank : 148)	NC score	0.028490 (rank : 369)
Query Neighborhood Hits	288	Target Neighborhood Hits	225	Shared Neighborhood Hits	19
SwissProt Accessions	Q8VHJ7, Q8C1C0	Gene names	Ppargc1b, Errl1, Pgc1, Pgc1b, Ppargc1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta protein) (PGC-1beta) (ERR ligand 1) (PPARGC-1-beta) (PGC-1-beta).

RP1L1_HUMAN
θ value	2.36792 (rank : 149)	NC score	0.079541 (rank : 105)
Query Neighborhood Hits	288	Target Neighborhood Hits	1072	Shared Neighborhood Hits	110
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

RPGR_HUMAN
θ value	2.36792 (rank : 150)	NC score	0.022489 (rank : 388)
Query Neighborhood Hits	288	Target Neighborhood Hits	279	Shared Neighborhood Hits	18
SwissProt Accessions	Q92834, O00702, O00737, Q8N5T6, Q93039, Q9HD29, Q9UMR1	Gene names	RPGR, RP3, XLRP3
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator.

SHC1_HUMAN
θ value	2.36792 (rank : 151)	NC score	0.058068 (rank : 235)
Query Neighborhood Hits	288	Target Neighborhood Hits	170	Shared Neighborhood Hits	22
SwissProt Accessions	P29353, O15290, Q8N4K5, Q96CL1	Gene names	SHC1, SHC, SHCA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

SHC1_MOUSE
θ value	2.36792 (rank : 152)	NC score	0.059063 (rank : 224)
Query Neighborhood Hits	288	Target Neighborhood Hits	180	Shared Neighborhood Hits	24
SwissProt Accessions	P98083, Q3U2Q7, Q8BFY3, Q8K4C6, Q8K4C7	Gene names	Shc1, Shc, ShcA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

SHC2_MOUSE
θ value	2.36792 (rank : 153)	NC score	0.048785 (rank : 314)
Query Neighborhood Hits	288	Target Neighborhood Hits	144	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BMC3	Gene names	Shc2, Sck, ShcB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck) (Protein Sli).

SI1L3_HUMAN
θ value	2.36792 (rank : 154)	NC score	0.020801 (rank : 391)
Query Neighborhood Hits	288	Target Neighborhood Hits	305	Shared Neighborhood Hits	30
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

TMC8_HUMAN
θ value	2.36792 (rank : 155)	NC score	0.019527 (rank : 396)
Query Neighborhood Hits	288	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IU68, Q8IWU7, Q8N358, Q8NF04	Gene names	TMC8, EVER2, EVIN2
Domain Architecture	No domain graphic available
Description	Transmembrane channel-like protein 8 (Epidermodysplasia verruciformis protein 2).

ARHG7_HUMAN
θ value	3.0926 (rank : 156)	NC score	0.095440 (rank : 59)
Query Neighborhood Hits	288	Target Neighborhood Hits	347	Shared Neighborhood Hits	59
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

BIM_HUMAN
θ value	3.0926 (rank : 157)	NC score	0.044330 (rank : 324)
Query Neighborhood Hits	288	Target Neighborhood Hits	134	Shared Neighborhood Hits	33
SwissProt Accessions	O43521, O43522	Gene names	BCL2L11, BIM
Domain Architecture
Description	Bcl-2-like protein 11 (Bcl2-interacting mediator of cell death).

BIN1_HUMAN
θ value	3.0926 (rank : 158)	NC score	0.080236 (rank : 101)
Query Neighborhood Hits	288	Target Neighborhood Hits	335	Shared Neighborhood Hits	70
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

CO6A1_MOUSE
θ value	3.0926 (rank : 159)	NC score	0.051981 (rank : 294)
Query Neighborhood Hits	288	Target Neighborhood Hits	241	Shared Neighborhood Hits	43
SwissProt Accessions	Q04857	Gene names	Col6a1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

CO8A1_HUMAN
θ value	3.0926 (rank : 160)	NC score	0.046333 (rank : 319)
Query Neighborhood Hits	288	Target Neighborhood Hits	288	Shared Neighborhood Hits	47
SwissProt Accessions	P27658, Q96D07	Gene names	COL8A1
Domain Architecture
Description	Collagen alpha-1(VIII) chain precursor (Endothelial collagen).

EVL_HUMAN
θ value	3.0926 (rank : 161)	NC score	0.038259 (rank : 340)
Query Neighborhood Hits	288	Target Neighborhood Hits	260	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UI08, O95884, Q7Z522, Q8TBV1, Q9UF25, Q9UIC2	Gene names	EVL, RNB6
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

HIPK3_HUMAN
θ value	3.0926 (rank : 162)	NC score	0.005467 (rank : 437)
Query Neighborhood Hits	288	Target Neighborhood Hits	867	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H422, O14632, Q2PBG4, Q2PBG5, Q92632, Q9HAS2	Gene names	HIPK3, DYRK6, FIST3, PKY
Domain Architecture	No domain graphic available
Description	Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Homolog of protein kinase YAK1) (Fas-interacting serine/threonine-protein kinase) (FIST) (Androgen receptor-interacting nuclear protein kinase) (ANPK).

MAP9_MOUSE
θ value	3.0926 (rank : 163)	NC score	0.028772 (rank : 368)
Query Neighborhood Hits	288	Target Neighborhood Hits	529	Shared Neighborhood Hits	25
SwissProt Accessions	Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7	Gene names	Map9, Asap
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

MELPH_HUMAN
θ value	3.0926 (rank : 164)	NC score	0.027129 (rank : 377)
Query Neighborhood Hits	288	Target Neighborhood Hits	145	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BV36, Q9HA71	Gene names	MLPH, SLAC2A
Domain Architecture	No domain graphic available
Description	Melanophilin (Exophilin-3) (Synaptotagmin-like protein 2a) (Slp homolog lacking C2 domains a).

MYCL1_MOUSE
θ value	3.0926 (rank : 165)	NC score	0.025328 (rank : 381)
Query Neighborhood Hits	288	Target Neighborhood Hits	123	Shared Neighborhood Hits	14
SwissProt Accessions	P10166, Q5FWI7	Gene names	Mycl1, Lmyc1, Mycl
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

NFIA_HUMAN
θ value	3.0926 (rank : 166)	NC score	0.023306 (rank : 386)
Query Neighborhood Hits	288	Target Neighborhood Hits	65	Shared Neighborhood Hits	16
SwissProt Accessions	Q12857, Q9H3X9, Q9P2A9	Gene names	NFIA, KIAA1439
Domain Architecture
Description	Nuclear factor 1 A-type (Nuclear factor 1/A) (NF1-A) (NFI-A) (NF-I/A) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

PACN2_HUMAN
θ value	3.0926 (rank : 167)	NC score	0.104651 (rank : 44)
Query Neighborhood Hits	288	Target Neighborhood Hits	339	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UNF0, O95921, Q96HV9, Q9H0D3, Q9NPN1, Q9Y4V2	Gene names	PACSIN2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

PACN3_HUMAN
θ value	3.0926 (rank : 168)	NC score	0.109614 (rank : 37)
Query Neighborhood Hits	288	Target Neighborhood Hits	385	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UKS6, Q9H331, Q9NWV9	Gene names	PACSIN3
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) (Endophilin I).

PACN3_MOUSE
θ value	3.0926 (rank : 169)	NC score	0.108538 (rank : 39)
Query Neighborhood Hits	288	Target Neighborhood Hits	380	Shared Neighborhood Hits	61
SwissProt Accessions	Q99JB8, Q9EQP9	Gene names	Pacsin3
Domain Architecture
Description	Protein kinase C and casein kinase II substrate protein 3.

PO6F1_MOUSE
θ value	3.0926 (rank : 170)	NC score	0.012821 (rank : 419)
Query Neighborhood Hits	288	Target Neighborhood Hits	581	Shared Neighborhood Hits	32
SwissProt Accessions	Q07916, Q91XK3	Gene names	Pou6f1, Emb
Domain Architecture
Description	POU domain, class 6, transcription factor 1 (Octamer-binding transcription factor EMB) (Transcription regulatory protein MCP-1).

PSL1_HUMAN
θ value	3.0926 (rank : 171)	NC score	0.055325 (rank : 256)
Query Neighborhood Hits	288	Target Neighborhood Hits	650	Shared Neighborhood Hits	93
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

RN167_HUMAN
θ value	3.0926 (rank : 172)	NC score	0.013685 (rank : 416)
Query Neighborhood Hits	288	Target Neighborhood Hits	157	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H6Y7, Q6XYE0, Q8NDC1, Q9Y3V1	Gene names	RNF167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RTN4_MOUSE
θ value	3.0926 (rank : 173)	NC score	0.040509 (rank : 337)
Query Neighborhood Hits	288	Target Neighborhood Hits	341	Shared Neighborhood Hits	32
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

SPEG_MOUSE
θ value	3.0926 (rank : 174)	NC score	0.027210 (rank : 375)
Query Neighborhood Hits	288	Target Neighborhood Hits	1959	Shared Neighborhood Hits	106
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

VAV_MOUSE
θ value	3.0926 (rank : 175)	NC score	0.073521 (rank : 137)
Query Neighborhood Hits	288	Target Neighborhood Hits	430	Shared Neighborhood Hits	63
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

WASIP_MOUSE
θ value	3.0926 (rank : 176)	NC score	0.072990 (rank : 141)
Query Neighborhood Hits	288	Target Neighborhood Hits	392	Shared Neighborhood Hits	50
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

WASP_MOUSE
θ value	3.0926 (rank : 177)	NC score	0.062970 (rank : 191)
Query Neighborhood Hits	288	Target Neighborhood Hits	223	Shared Neighborhood Hits	33
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

ARHG6_HUMAN
θ value	4.03905 (rank : 178)	NC score	0.088663 (rank : 72)
Query Neighborhood Hits	288	Target Neighborhood Hits	376	Shared Neighborhood Hits	59
SwissProt Accessions	Q15052, Q15396, Q5JQ66, Q86XH0	Gene names	ARHGEF6, COOL2, KIAA0006, PIXA
Domain Architecture
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).

ARHG7_MOUSE
θ value	4.03905 (rank : 179)	NC score	0.097111 (rank : 55)
Query Neighborhood Hits	288	Target Neighborhood Hits	396	Shared Neighborhood Hits	61
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

CAC1C_MOUSE
θ value	4.03905 (rank : 180)	NC score	0.009811 (rank : 426)
Query Neighborhood Hits	288	Target Neighborhood Hits	130	Shared Neighborhood Hits	10
SwissProt Accessions	Q01815, Q04476, Q61242, Q99242	Gene names	Cacna1c, Cach2, Cacn2, Cacnl1a1, Cchl1a1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Mouse brain class C) (MBC) (MELC-CC).

CO039_MOUSE
θ value	4.03905 (rank : 181)	NC score	0.077313 (rank : 119)
Query Neighborhood Hits	288	Target Neighborhood Hits	445	Shared Neighborhood Hits	53
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

COGA1_HUMAN
θ value	4.03905 (rank : 182)	NC score	0.060643 (rank : 212)
Query Neighborhood Hits	288	Target Neighborhood Hits	345	Shared Neighborhood Hits	61
SwissProt Accessions	Q07092	Gene names	COL16A1
Domain Architecture
Description	Collagen alpha-1(XVI) chain precursor.

CQ028_HUMAN
θ value	4.03905 (rank : 183)	NC score	0.032145 (rank : 355)
Query Neighborhood Hits	288	Target Neighborhood Hits	56	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IV36, Q8N5L6, Q8TE83, Q9NT34	Gene names	C17orf28, DMC1
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C17orf28 (Down-regulated in multiple cancers- 1).

DP13B_HUMAN
θ value	4.03905 (rank : 184)	NC score	0.061328 (rank : 205)
Query Neighborhood Hits	288	Target Neighborhood Hits	58	Shared Neighborhood Hits	12
SwissProt Accessions	Q8NEU8, Q8N4R7, Q9NVL2	Gene names	DIP13B, APPL2
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 beta (Dip13 beta) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 2).

FOXE3_HUMAN
θ value	4.03905 (rank : 185)	NC score	0.005221 (rank : 438)
Query Neighborhood Hits	288	Target Neighborhood Hits	112	Shared Neighborhood Hits	8
SwissProt Accessions	Q13461, Q5SVY9, Q9NQV9	Gene names	FOXE3, FKHL12, FREAC8
Domain Architecture
Description	Forkhead box protein E3 (Forkhead-related protein FKHL12) (Forkhead- related transcription factor 8) (FREAC-8).

FZD8_MOUSE
θ value	4.03905 (rank : 186)	NC score	0.008680 (rank : 428)
Query Neighborhood Hits	288	Target Neighborhood Hits	89	Shared Neighborhood Hits	7
SwissProt Accessions	Q61091	Gene names	Fzd8
Domain Architecture
Description	Frizzled-8 precursor (Fz-8) (mFz8).

HCN2_HUMAN
θ value	4.03905 (rank : 187)	NC score	0.029283 (rank : 364)
Query Neighborhood Hits	288	Target Neighborhood Hits	369	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

HES6_HUMAN
θ value	4.03905 (rank : 188)	NC score	0.016802 (rank : 408)
Query Neighborhood Hits	288	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	Q96HZ4, Q8N2J2, Q96T93, Q9P2S3	Gene names	HES6
Domain Architecture	No domain graphic available
Description	Transcription cofactor HES-6 (Hairy and enhancer of split 6) (C- HAIRY1).

HXD3_MOUSE
θ value	4.03905 (rank : 189)	NC score	0.007623 (rank : 429)
Query Neighborhood Hits	288	Target Neighborhood Hits	435	Shared Neighborhood Hits	17
SwissProt Accessions	P09027, Q3UUD3	Gene names	Hoxd3, Hox-4.1, Hoxd-3
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4.1) (Homeobox protein MH-19).

KCNH2_MOUSE
θ value	4.03905 (rank : 190)	NC score	0.010537 (rank : 422)
Query Neighborhood Hits	288	Target Neighborhood Hits	165	Shared Neighborhood Hits	11
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

LIMD1_HUMAN
θ value	4.03905 (rank : 191)	NC score	0.013340 (rank : 417)
Query Neighborhood Hits	288	Target Neighborhood Hits	201	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UGP4, Q9BQQ9, Q9NQ47	Gene names	LIMD1
Domain Architecture
Description	LIM domain-containing protein 1.

NFIA_MOUSE
θ value	4.03905 (rank : 192)	NC score	0.022312 (rank : 389)
Query Neighborhood Hits	288	Target Neighborhood Hits	69	Shared Neighborhood Hits	16
SwissProt Accessions	Q02780, P70250, P70251, Q3UUZ2, Q61960, Q8VBT5, Q9R1G5	Gene names	Nfia
Domain Architecture
Description	Nuclear factor 1 A-type (Nuclear factor 1/A) (NF1-A) (NFI-A) (NF-I/A) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

NHS_HUMAN
θ value	4.03905 (rank : 193)	NC score	0.042713 (rank : 331)
Query Neighborhood Hits	288	Target Neighborhood Hits	198	Shared Neighborhood Hits	19
SwissProt Accessions	Q6T4R5, Q5J7Q0, Q5J7Q1, Q68DR5	Gene names	NHS
Domain Architecture	No domain graphic available
Description	Nance-Horan syndrome protein (Congenital cataracts and dental anomalies protein).

PRPE_HUMAN
θ value	4.03905 (rank : 194)	NC score	0.099866 (rank : 50)
Query Neighborhood Hits	288	Target Neighborhood Hits	44	Shared Neighborhood Hits	11
SwissProt Accessions	P02811	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide P-E (IB-9).

RP3A_HUMAN
θ value	4.03905 (rank : 195)	NC score	0.031331 (rank : 357)
Query Neighborhood Hits	288	Target Neighborhood Hits	305	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SC24D_HUMAN
θ value	4.03905 (rank : 196)	NC score	0.027196 (rank : 376)
Query Neighborhood Hits	288	Target Neighborhood Hits	173	Shared Neighborhood Hits	27
SwissProt Accessions	O94855	Gene names	SEC24D, KIAA0755
Domain Architecture
Description	Protein transport protein Sec24D (SEC24-related protein D).

TTC15_HUMAN
θ value	4.03905 (rank : 197)	NC score	0.043939 (rank : 327)
Query Neighborhood Hits	288	Target Neighborhood Hits	112	Shared Neighborhood Hits	22
SwissProt Accessions	Q8WVT3, Q8WVW1, Q9Y395	Gene names	TTC15
Domain Architecture
Description	Tetratricopeptide repeat protein 15 (TPR repeat protein 15).

TXK_MOUSE
θ value	4.03905 (rank : 198)	NC score	0.015388 (rank : 412)
Query Neighborhood Hits	288	Target Neighborhood Hits	980	Shared Neighborhood Hits	56
SwissProt Accessions	P42682	Gene names	Txk, Rlk
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18) (Resting lymphocyte kinase).

ANR11_HUMAN
θ value	5.27518 (rank : 199)	NC score	0.040969 (rank : 334)
Query Neighborhood Hits	288	Target Neighborhood Hits	1289	Shared Neighborhood Hits	83
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

CO5A1_HUMAN
θ value	5.27518 (rank : 200)	NC score	0.064402 (rank : 179)
Query Neighborhood Hits	288	Target Neighborhood Hits	434	Shared Neighborhood Hits	74
SwissProt Accessions	P20908, Q15094, Q5SUX4	Gene names	COL5A1
Domain Architecture
Description	Collagen alpha-1(V) chain precursor.

CO5A1_MOUSE
θ value	5.27518 (rank : 201)	NC score	0.062811 (rank : 193)
Query Neighborhood Hits	288	Target Neighborhood Hits	419	Shared Neighborhood Hits	70
SwissProt Accessions	O88207	Gene names	Col5a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(V) chain precursor.

CO7A1_HUMAN
θ value	5.27518 (rank : 202)	NC score	0.057815 (rank : 238)
Query Neighborhood Hits	288	Target Neighborhood Hits	807	Shared Neighborhood Hits	84
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

COFA1_MOUSE
θ value	5.27518 (rank : 203)	NC score	0.062675 (rank : 198)
Query Neighborhood Hits	288	Target Neighborhood Hits	305	Shared Neighborhood Hits	56
SwissProt Accessions	O35206, Q9EQD9	Gene names	Col15a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV)].

COG8_MOUSE
θ value	5.27518 (rank : 204)	NC score	0.028197 (rank : 371)
Query Neighborhood Hits	288	Target Neighborhood Hits	147	Shared Neighborhood Hits	21
SwissProt Accessions	Q9JJA2	Gene names	Cog8
Domain Architecture
Description	Conserved oligomeric Golgi complex component 8.

CSKI1_HUMAN
θ value	5.27518 (rank : 205)	NC score	0.049937 (rank : 311)
Query Neighborhood Hits	288	Target Neighborhood Hits	997	Shared Neighborhood Hits	112
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

DOT1L_HUMAN
θ value	5.27518 (rank : 206)	NC score	0.044616 (rank : 323)
Query Neighborhood Hits	288	Target Neighborhood Hits	660	Shared Neighborhood Hits	59
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

DTX1_MOUSE
θ value	5.27518 (rank : 207)	NC score	0.018589 (rank : 403)
Query Neighborhood Hits	288	Target Neighborhood Hits	99	Shared Neighborhood Hits	14
SwissProt Accessions	Q61010, Q3TER5, Q8C2H2, Q9ER09	Gene names	Dtx1
Domain Architecture
Description	Protein deltex-1 (Deltex-1) (Deltex1) (mDTX1) (FXI-T1).

EPN3_MOUSE
θ value	5.27518 (rank : 208)	NC score	0.028448 (rank : 370)
Query Neighborhood Hits	288	Target Neighborhood Hits	312	Shared Neighborhood Hits	49
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

GP152_HUMAN
θ value	5.27518 (rank : 209)	NC score	0.018513 (rank : 404)
Query Neighborhood Hits	288	Target Neighborhood Hits	636	Shared Neighborhood Hits	38
SwissProt Accessions	Q8TDT2, Q86SM0	Gene names	GPR152, PGR5
Domain Architecture
Description	Probable G-protein coupled receptor 152 (G-protein coupled receptor PGR5).

HXA3_HUMAN
θ value	5.27518 (rank : 210)	NC score	0.016246 (rank : 411)
Query Neighborhood Hits	288	Target Neighborhood Hits	535	Shared Neighborhood Hits	37
SwissProt Accessions	O43365	Gene names	HOXA3, HOX1E
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1E).

JPH2_MOUSE
θ value	5.27518 (rank : 211)	NC score	0.038075 (rank : 341)
Query Neighborhood Hits	288	Target Neighborhood Hits	279	Shared Neighborhood Hits	43
SwissProt Accessions	Q9ET78, Q9ET79	Gene names	Jph2, Jp2
Domain Architecture	No domain graphic available
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

KIF4A_MOUSE
θ value	5.27518 (rank : 212)	NC score	0.009925 (rank : 425)
Query Neighborhood Hits	288	Target Neighborhood Hits	1033	Shared Neighborhood Hits	35
SwissProt Accessions	P33174	Gene names	Kif4a, Kif4, Kns4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

LEO1_HUMAN
θ value	5.27518 (rank : 213)	NC score	0.047272 (rank : 317)
Query Neighborhood Hits	288	Target Neighborhood Hits	958	Shared Neighborhood Hits	35
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

LRC50_HUMAN
θ value	5.27518 (rank : 214)	NC score	0.028773 (rank : 367)
Query Neighborhood Hits	288	Target Neighborhood Hits	275	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NEP3, Q69YI8, Q69YJ0, Q96LP3	Gene names	LRRC50
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 50.

M3K12_MOUSE
θ value	5.27518 (rank : 215)	NC score	0.004610 (rank : 439)
Query Neighborhood Hits	288	Target Neighborhood Hits	957	Shared Neighborhood Hits	30
SwissProt Accessions	Q60700, P70286, Q3TLL7, Q8C4N7, Q8CBX3, Q8CDL6	Gene names	Map3k12, Zpk
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

PAF49_MOUSE
θ value	5.27518 (rank : 216)	NC score	0.058532 (rank : 232)
Query Neighborhood Hits	288	Target Neighborhood Hits	48	Shared Neighborhood Hits	5
SwissProt Accessions	Q76KJ5, Q8K0Y9	Gene names	Cd3eap, Ase1, Paf49
Domain Architecture	No domain graphic available
Description	RNA polymerase I-associated factor PAF49 (Anti-sense to ERCC-1 protein) (ASE-1) (CD3-epsilon-associated protein) (CD3E-associated protein).

PRGR_HUMAN
θ value	5.27518 (rank : 217)	NC score	0.006962 (rank : 434)
Query Neighborhood Hits	288	Target Neighborhood Hits	163	Shared Neighborhood Hits	11
SwissProt Accessions	P06401, Q9UPF7	Gene names	PGR, NR3C3
Domain Architecture
Description	Progesterone receptor (PR).

RGS14_HUMAN
θ value	5.27518 (rank : 218)	NC score	0.019944 (rank : 394)
Query Neighborhood Hits	288	Target Neighborhood Hits	77	Shared Neighborhood Hits	8
SwissProt Accessions	O43566, O43565, Q8TD62	Gene names	RGS14
Domain Architecture
Description	Regulator of G-protein signaling 14 (RGS14).

SFPQ_MOUSE
θ value	5.27518 (rank : 219)	NC score	0.052485 (rank : 286)
Query Neighborhood Hits	288	Target Neighborhood Hits	958	Shared Neighborhood Hits	64
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

SNX9_HUMAN
θ value	5.27518 (rank : 220)	NC score	0.078990 (rank : 108)
Query Neighborhood Hits	288	Target Neighborhood Hits	148	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y5X1, Q9BSI7, Q9BVM1, Q9UJH6, Q9UP20	Gene names	SNX9, SH3PX1
Domain Architecture
Description	Sorting nexin-9 (SH3 and PX domain-containing protein 1) (SDP1 protein).

SPAT2_HUMAN
θ value	5.27518 (rank : 221)	NC score	0.025470 (rank : 379)
Query Neighborhood Hits	288	Target Neighborhood Hits	39	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UM82, O94857	Gene names	SPATA2, KIAA0757, PD1
Domain Architecture	No domain graphic available
Description	Spermatogenesis-associated protein 2 (Spermatogenesis-associated protein PD1).

VASP_HUMAN
θ value	5.27518 (rank : 222)	NC score	0.043994 (rank : 326)
Query Neighborhood Hits	288	Target Neighborhood Hits	201	Shared Neighborhood Hits	35
SwissProt Accessions	P50552, Q6PIZ1, Q93035	Gene names	VASP
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

WASL_HUMAN
θ value	5.27518 (rank : 223)	NC score	0.096563 (rank : 57)
Query Neighborhood Hits	288	Target Neighborhood Hits	312	Shared Neighborhood Hits	42
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

X3CL1_HUMAN
θ value	5.27518 (rank : 224)	NC score	0.021808 (rank : 390)
Query Neighborhood Hits	288	Target Neighborhood Hits	152	Shared Neighborhood Hits	18
SwissProt Accessions	P78423, O00672	Gene names	CX3CL1, A-152E5.2, FKN, NTT, SCYD1
Domain Architecture
Description	Fractalkine precursor (CX3CL1) (Neurotactin) (CX3C membrane-anchored chemokine) (Small inducible cytokine D1).

ADPGK_HUMAN
θ value	6.88961 (rank : 225)	NC score	0.014415 (rank : 414)
Query Neighborhood Hits	288	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BRR6, Q8NBI1, Q8WZ90, Q96NF8, Q9H0A7	Gene names	ADPGK
Domain Architecture	No domain graphic available
Description	ADP-dependent glucokinase (EC 2.7.1.147) (ADPGK) (ADP-GK) (RbBP-35).

ARI1A_HUMAN
θ value	6.88961 (rank : 226)	NC score	0.055452 (rank : 252)
Query Neighborhood Hits	288	Target Neighborhood Hits	787	Shared Neighborhood Hits	87
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

BAT2_MOUSE
θ value	6.88961 (rank : 227)	NC score	0.066788 (rank : 164)
Query Neighborhood Hits	288	Target Neighborhood Hits	947	Shared Neighborhood Hits	116
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BAZ2A_MOUSE
θ value	6.88961 (rank : 228)	NC score	0.062737 (rank : 195)
Query Neighborhood Hits	288	Target Neighborhood Hits	744	Shared Neighborhood Hits	75
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

CO8A1_MOUSE
θ value	6.88961 (rank : 229)	NC score	0.044321 (rank : 325)
Query Neighborhood Hits	288	Target Neighborhood Hits	251	Shared Neighborhood Hits	45
SwissProt Accessions	Q00780, Q9D2V4	Gene names	Col8a1
Domain Architecture
Description	Collagen alpha-1(VIII) chain precursor.

CO8A2_HUMAN
θ value	6.88961 (rank : 230)	NC score	0.047917 (rank : 316)
Query Neighborhood Hits	288	Target Neighborhood Hits	299	Shared Neighborhood Hits	51
SwissProt Accessions	P25067, Q8TEJ5	Gene names	COL8A2
Domain Architecture
Description	Collagen alpha-2(VIII) chain precursor (Endothelial collagen).

COHA1_MOUSE
θ value	6.88961 (rank : 231)	NC score	0.059302 (rank : 221)
Query Neighborhood Hits	288	Target Neighborhood Hits	414	Shared Neighborhood Hits	62
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

FCN1_MOUSE
θ value	6.88961 (rank : 232)	NC score	0.020127 (rank : 393)
Query Neighborhood Hits	288	Target Neighborhood Hits	173	Shared Neighborhood Hits	29
SwissProt Accessions	O70165	Gene names	Fcn1, Fcna
Domain Architecture
Description	Ficolin-1 precursor (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin A) (M-Ficolin).

IKBE_MOUSE
θ value	6.88961 (rank : 233)	NC score	0.019344 (rank : 398)
Query Neighborhood Hits	288	Target Neighborhood Hits	308	Shared Neighborhood Hits	18
SwissProt Accessions	O54910, Q3U686, Q9CZZ9, Q9D7U3	Gene names	Nfkbie, Ikbe
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKB-E).

INVS_MOUSE
θ value	6.88961 (rank : 234)	NC score	0.030693 (rank : 359)
Query Neighborhood Hits	288	Target Neighborhood Hits	609	Shared Neighborhood Hits	53
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

MAP1A_HUMAN
θ value	6.88961 (rank : 235)	NC score	0.048622 (rank : 315)
Query Neighborhood Hits	288	Target Neighborhood Hits	1626	Shared Neighborhood Hits	114
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MAST3_HUMAN
θ value	6.88961 (rank : 236)	NC score	0.008806 (rank : 427)
Query Neighborhood Hits	288	Target Neighborhood Hits	1128	Shared Neighborhood Hits	45
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

NGN2_MOUSE
θ value	6.88961 (rank : 237)	NC score	0.007397 (rank : 432)
Query Neighborhood Hits	288	Target Neighborhood Hits	106	Shared Neighborhood Hits	6
SwissProt Accessions	P70447, P70237	Gene names	Neurog2, Ath4a, Atoh4, Ngn2
Domain Architecture
Description	Neurogenin 2 (Atonal protein homolog 4) (Helix-loop-helix protein mATH-4A) (MATH4A).

PCNT_HUMAN
θ value	6.88961 (rank : 238)	NC score	0.017277 (rank : 407)
Query Neighborhood Hits	288	Target Neighborhood Hits	1551	Shared Neighborhood Hits	69
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

PDCD7_HUMAN
θ value	6.88961 (rank : 239)	NC score	0.032931 (rank : 353)
Query Neighborhood Hits	288	Target Neighborhood Hits	255	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N8D1, Q96AK8, Q9Y6D7	Gene names	PDCD7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18) (HES18).

PIM2_MOUSE
θ value	6.88961 (rank : 240)	NC score	0.002303 (rank : 442)
Query Neighborhood Hits	288	Target Neighborhood Hits	809	Shared Neighborhood Hits	15
SwissProt Accessions	Q62070, Q62071, Q62072	Gene names	Pim2, Pim-2
Domain Architecture
Description	Serine/threonine-protein kinase Pim-2 (EC 2.7.11.1).

RAPH1_HUMAN
θ value	6.88961 (rank : 241)	NC score	0.065137 (rank : 176)
Query Neighborhood Hits	288	Target Neighborhood Hits	593	Shared Neighborhood Hits	64
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

RP3A_MOUSE
θ value	6.88961 (rank : 242)	NC score	0.032785 (rank : 354)
Query Neighborhood Hits	288	Target Neighborhood Hits	510	Shared Neighborhood Hits	65
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

RUSC1_MOUSE
θ value	6.88961 (rank : 243)	NC score	0.053611 (rank : 275)
Query Neighborhood Hits	288	Target Neighborhood Hits	206	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BG26, Q6PHT9	Gene names	Rusc1
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1.

RXRB_MOUSE
θ value	6.88961 (rank : 244)	NC score	0.007344 (rank : 433)
Query Neighborhood Hits	288	Target Neighborhood Hits	230	Shared Neighborhood Hits	21
SwissProt Accessions	P28704, P33243	Gene names	Rxrb, Nr2b2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta) (MHC class I regulatory element-binding protein H-2RIIBP).

SEM6C_MOUSE
θ value	6.88961 (rank : 245)	NC score	0.013889 (rank : 415)
Query Neighborhood Hits	288	Target Neighborhood Hits	352	Shared Neighborhood Hits	59
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

SYTL1_MOUSE
θ value	6.88961 (rank : 246)	NC score	0.016448 (rank : 409)
Query Neighborhood Hits	288	Target Neighborhood Hits	314	Shared Neighborhood Hits	21
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

TCAL3_HUMAN
θ value	6.88961 (rank : 247)	NC score	0.029910 (rank : 362)
Query Neighborhood Hits	288	Target Neighborhood Hits	274	Shared Neighborhood Hits	18
SwissProt Accessions	Q969E4	Gene names	TCEAL3
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 3 (TCEA-like protein 3) (Transcription elongation factor S-II protein-like 3).

TERF2_MOUSE
θ value	6.88961 (rank : 248)	NC score	0.020667 (rank : 392)
Query Neighborhood Hits	288	Target Neighborhood Hits	128	Shared Neighborhood Hits	11
SwissProt Accessions	O35144	Gene names	Terf2, Trf2
Domain Architecture
Description	Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein).

TPOR_HUMAN
θ value	6.88961 (rank : 249)	NC score	0.013041 (rank : 418)
Query Neighborhood Hits	288	Target Neighborhood Hits	70	Shared Neighborhood Hits	4
SwissProt Accessions	P40238	Gene names	MPL, TPOR
Domain Architecture
Description	Thrombopoietin receptor precursor (TPO-R) (Myeloproliferative leukemia protein) (C-mpl) (CD110 antigen).

ZC3H6_MOUSE
θ value	6.88961 (rank : 250)	NC score	0.018886 (rank : 399)
Query Neighborhood Hits	288	Target Neighborhood Hits	239	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BYK8, Q80UK3, Q8C1H1, Q9D604	Gene names	Zc3h6, Zc3hdc6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

ZMYM3_HUMAN
θ value	6.88961 (rank : 251)	NC score	0.026224 (rank : 378)
Query Neighborhood Hits	288	Target Neighborhood Hits	223	Shared Neighborhood Hits	27
SwissProt Accessions	Q14202, O15089	Gene names	ZMYM3, DXS6673E, KIAA0385, ZNF261
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 3 (Zinc finger protein 261).

ZN219_HUMAN
θ value	6.88961 (rank : 252)	NC score	0.002758 (rank : 441)
Query Neighborhood Hits	288	Target Neighborhood Hits	876	Shared Neighborhood Hits	31
SwissProt Accessions	Q9P2Y4, Q8IYC1, Q9BW28	Gene names	ZNF219
Domain Architecture	No domain graphic available
Description	Zinc finger protein 219.

AP2A2_MOUSE
θ value	8.99809 (rank : 253)	NC score	0.005522 (rank : 436)
Query Neighborhood Hits	288	Target Neighborhood Hits	46	Shared Neighborhood Hits	5
SwissProt Accessions	P17427, Q921V0	Gene names	Ap2a2, Adtab
Domain Architecture
Description	AP-2 complex subunit alpha-2 (Adapter-related protein complex 2 alpha- 2 subunit) (Alpha-adaptin C) (Adaptor protein complex AP-2 alpha-2 subunit) (Clathrin assembly protein complex 2 alpha-C large chain) (100 kDa coated vesicle protein C) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit).

CAC1E_MOUSE
θ value	8.99809 (rank : 254)	NC score	0.012407 (rank : 420)
Query Neighborhood Hits	288	Target Neighborhood Hits	167	Shared Neighborhood Hits	11
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CF051_HUMAN
θ value	8.99809 (rank : 255)	NC score	0.019412 (rank : 397)
Query Neighborhood Hits	288	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q969F1	Gene names	C6orf51
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf51.

CK024_HUMAN
θ value	8.99809 (rank : 256)	NC score	0.050190 (rank : 308)
Query Neighborhood Hits	288	Target Neighborhood Hits	408	Shared Neighborhood Hits	52
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

COBA1_HUMAN
θ value	8.99809 (rank : 257)	NC score	0.061441 (rank : 203)
Query Neighborhood Hits	288	Target Neighborhood Hits	491	Shared Neighborhood Hits	71
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

COCA1_MOUSE
θ value	8.99809 (rank : 258)	NC score	0.037948 (rank : 343)
Query Neighborhood Hits	288	Target Neighborhood Hits	467	Shared Neighborhood Hits	54
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

COEA1_HUMAN
θ value	8.99809 (rank : 259)	NC score	0.043624 (rank : 328)
Query Neighborhood Hits	288	Target Neighborhood Hits	427	Shared Neighborhood Hits	52
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

DP13B_MOUSE
θ value	8.99809 (rank : 260)	NC score	0.057056 (rank : 244)
Query Neighborhood Hits	288	Target Neighborhood Hits	58	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K3G9, Q99LT7	Gene names	Dip13b, Appl2, Dip3b
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 beta (Dip13 beta) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 2).

ECHP_HUMAN
θ value	8.99809 (rank : 261)	NC score	0.007481 (rank : 431)
Query Neighborhood Hits	288	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q08426	Gene names	EHHADH, ECHD
Domain Architecture
Description	Peroxisomal bifunctional enzyme (PBE) (PBFE) [Includes: Enoyl-CoA hydratase (EC 4.2.1.17); 3,2-trans-enoyl-CoA isomerase (EC 5.3.3.8); 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35)].

EMID1_MOUSE
θ value	8.99809 (rank : 262)	NC score	0.045834 (rank : 321)
Query Neighborhood Hits	288	Target Neighborhood Hits	230	Shared Neighborhood Hits	41
SwissProt Accessions	Q91VF5	Gene names	Emid1, Emu1
Domain Architecture	No domain graphic available
Description	EMI domain-containing protein 1 precursor (Protein Emu1) (Emilin and multimerin domain-containing protein 1).

GPR88_HUMAN
θ value	8.99809 (rank : 263)	NC score	0.018678 (rank : 402)
Query Neighborhood Hits	288	Target Neighborhood Hits	172	Shared Neighborhood Hits	3
SwissProt Accessions	Q9GZN0, Q6VN48	Gene names	GPR88, STRG
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 88 (Striatum-specific G-protein coupled receptor).

HXC11_HUMAN
θ value	8.99809 (rank : 264)	NC score	0.004201 (rank : 440)
Query Neighborhood Hits	288	Target Neighborhood Hits	349	Shared Neighborhood Hits	10
SwissProt Accessions	O43248, Q96DH2	Gene names	HOXC11
Domain Architecture
Description	Homeobox protein Hox-C11.

HXD3_HUMAN
θ value	8.99809 (rank : 265)	NC score	0.007589 (rank : 430)
Query Neighborhood Hits	288	Target Neighborhood Hits	433	Shared Neighborhood Hits	22
SwissProt Accessions	P31249, Q99955, Q9BSC5	Gene names	HOXD3, HOX4A
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4A).

IF35_MOUSE
θ value	8.99809 (rank : 266)	NC score	0.037933 (rank : 344)
Query Neighborhood Hits	288	Target Neighborhood Hits	210	Shared Neighborhood Hits	27
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

MTSS1_MOUSE
θ value	8.99809 (rank : 267)	NC score	0.046700 (rank : 318)
Query Neighborhood Hits	288	Target Neighborhood Hits	592	Shared Neighborhood Hits	80
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

NFIC_HUMAN
θ value	8.99809 (rank : 268)	NC score	0.018355 (rank : 405)
Query Neighborhood Hits	288	Target Neighborhood Hits	59	Shared Neighborhood Hits	9
SwissProt Accessions	P08651, P08652, Q14932, Q9UPJ3, Q9UPJ9, Q9UPK0, Q9UPK1	Gene names	NFIC, NFI
Domain Architecture
Description	Nuclear factor 1 C-type (Nuclear factor 1/C) (NF1-C) (NFI-C) (NF-I/C) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

P85B_HUMAN
θ value	8.99809 (rank : 269)	NC score	0.046189 (rank : 320)
Query Neighborhood Hits	288	Target Neighborhood Hits	543	Shared Neighborhood Hits	41
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

P85B_MOUSE
θ value	8.99809 (rank : 270)	NC score	0.042742 (rank : 330)
Query Neighborhood Hits	288	Target Neighborhood Hits	519	Shared Neighborhood Hits	37
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

PGCA_HUMAN
θ value	8.99809 (rank : 271)	NC score	0.040877 (rank : 335)
Query Neighborhood Hits	288	Target Neighborhood Hits	821	Shared Neighborhood Hits	59
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

PRB4S_HUMAN
θ value	8.99809 (rank : 272)	NC score	0.084454 (rank : 89)
Query Neighborhood Hits	288	Target Neighborhood Hits	330	Shared Neighborhood Hits	51
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

PRP2_MOUSE
θ value	8.99809 (rank : 273)	NC score	0.094594 (rank : 61)
Query Neighborhood Hits	288	Target Neighborhood Hits	347	Shared Neighborhood Hits	43
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PRP5_HUMAN
θ value	8.99809 (rank : 274)	NC score	0.073422 (rank : 138)
Query Neighborhood Hits	288	Target Neighborhood Hits	108	Shared Neighborhood Hits	27
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

PTN23_HUMAN
θ value	8.99809 (rank : 275)	NC score	0.022795 (rank : 387)
Query Neighborhood Hits	288	Target Neighborhood Hits	646	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

RUSC1_HUMAN
θ value	8.99809 (rank : 276)	NC score	0.057272 (rank : 243)
Query Neighborhood Hits	288	Target Neighborhood Hits	226	Shared Neighborhood Hits	49
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

SEZ6L_HUMAN
θ value	8.99809 (rank : 277)	NC score	0.018182 (rank : 406)
Query Neighborhood Hits	288	Target Neighborhood Hits	289	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

SH3K1_HUMAN
θ value	8.99809 (rank : 278)	NC score	0.125903 (rank : 24)
Query Neighborhood Hits	288	Target Neighborhood Hits	341	Shared Neighborhood Hits	68
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

SRC8_HUMAN
θ value	8.99809 (rank : 279)	NC score	0.088830 (rank : 70)
Query Neighborhood Hits	288	Target Neighborhood Hits	269	Shared Neighborhood Hits	58
SwissProt Accessions	Q14247	Gene names	CTTN, EMS1
Domain Architecture
Description	Src substrate cortactin (Amplaxin) (Oncogene EMS1).

SRC8_MOUSE
θ value	8.99809 (rank : 280)	NC score	0.089800 (rank : 66)
Query Neighborhood Hits	288	Target Neighborhood Hits	292	Shared Neighborhood Hits	62
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

SRPK1_MOUSE
θ value	8.99809 (rank : 281)	NC score	0.006539 (rank : 435)
Query Neighborhood Hits	288	Target Neighborhood Hits	639	Shared Neighborhood Hits	13
SwissProt Accessions	O70551, O70193, Q99JT3	Gene names	Srpk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SRPK1 (EC 2.7.11.1) (Serine/arginine- rich protein-specific kinase 1) (SR-protein-specific kinase 1) (SFRS protein kinase 1).

STAC_HUMAN
θ value	8.99809 (rank : 282)	NC score	0.094759 (rank : 60)
Query Neighborhood Hits	288	Target Neighborhood Hits	276	Shared Neighborhood Hits	54
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

TAF4_HUMAN
θ value	8.99809 (rank : 283)	NC score	0.088098 (rank : 74)
Query Neighborhood Hits	288	Target Neighborhood Hits	687	Shared Neighborhood Hits	68
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

TB182_HUMAN
θ value	8.99809 (rank : 284)	NC score	0.075971 (rank : 124)
Query Neighborhood Hits	288	Target Neighborhood Hits	414	Shared Neighborhood Hits	60
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

TCAL5_HUMAN
θ value	8.99809 (rank : 285)	NC score	0.038825 (rank : 339)
Query Neighborhood Hits	288	Target Neighborhood Hits	806	Shared Neighborhood Hits	52
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

TGON2_HUMAN
θ value	8.99809 (rank : 286)	NC score	0.055204 (rank : 257)
Query Neighborhood Hits	288	Target Neighborhood Hits	1037	Shared Neighborhood Hits	78
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

VCIP1_MOUSE
θ value	8.99809 (rank : 287)	NC score	0.010190 (rank : 424)
Query Neighborhood Hits	288	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CDG3, Q7TMU9, Q8BP90	Gene names	Vcpip1, Vcip135
Domain Architecture
Description	Deubiquitinating protein VCIP135 (EC 3.4.22.-) (Valosin-containing protein p97/p47 complex-interacting protein p135) (Valosin-containing protein p97/p47 complex-interacting protein 1).

WIRE_HUMAN
θ value	8.99809 (rank : 288)	NC score	0.068650 (rank : 160)
Query Neighborhood Hits	288	Target Neighborhood Hits	329	Shared Neighborhood Hits	45
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

ABI1_HUMAN
θ value	θ > 10 (rank : 289)	NC score	0.074679 (rank : 133)
Query Neighborhood Hits	288	Target Neighborhood Hits	257	Shared Neighborhood Hits	62
SwissProt Accessions	Q8IZP0, O15147, O76049, O95060, Q5W070, Q5W072, Q8TB63, Q96S81, Q9NXZ9, Q9NYB8	Gene names	ABI1, SSH3BP1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Nap1-binding protein) (Nap1BP) (Abl-binding protein 4) (AblBP4).

ABI1_MOUSE
θ value	θ > 10 (rank : 290)	NC score	0.080105 (rank : 102)
Query Neighborhood Hits	288	Target Neighborhood Hits	246	Shared Neighborhood Hits	63
SwissProt Accessions	Q8CBW3, Q60747, Q91ZM5, Q923I9, Q99KH4	Gene names	Abi1, Ssh3bp1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Ablphilin-1).

ABI2_HUMAN
θ value	θ > 10 (rank : 291)	NC score	0.090891 (rank : 65)
Query Neighborhood Hits	288	Target Neighborhood Hits	350	Shared Neighborhood Hits	80
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

ABI2_MOUSE
θ value	θ > 10 (rank : 292)	NC score	0.084487 (rank : 88)
Query Neighborhood Hits	288	Target Neighborhood Hits	266	Shared Neighborhood Hits	63
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

ABI3_HUMAN
θ value	θ > 10 (rank : 293)	NC score	0.078513 (rank : 114)
Query Neighborhood Hits	288	Target Neighborhood Hits	227	Shared Neighborhood Hits	61
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

ABI3_MOUSE
θ value	θ > 10 (rank : 294)	NC score	0.068721 (rank : 159)
Query Neighborhood Hits	288	Target Neighborhood Hits	227	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

ALEX_HUMAN
θ value	θ > 10 (rank : 295)	NC score	0.051074 (rank : 304)
Query Neighborhood Hits	288	Target Neighborhood Hits	361	Shared Neighborhood Hits	39
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

AMPH_HUMAN
θ value	θ > 10 (rank : 296)	NC score	0.060184 (rank : 215)
Query Neighborhood Hits	288	Target Neighborhood Hits	455	Shared Neighborhood Hits	61
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

AMPH_MOUSE
θ value	θ > 10 (rank : 297)	NC score	0.058775 (rank : 227)
Query Neighborhood Hits	288	Target Neighborhood Hits	291	Shared Neighborhood Hits	52
SwissProt Accessions	Q7TQF7, Q8R1C4	Gene names	Amph, Amph1
Domain Architecture
Description	Amphiphysin.

APBA3_MOUSE
θ value	θ > 10 (rank : 298)	NC score	0.050425 (rank : 306)
Query Neighborhood Hits	288	Target Neighborhood Hits	174	Shared Neighborhood Hits	21
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

ARHG4_HUMAN
θ value	θ > 10 (rank : 299)	NC score	0.051534 (rank : 300)
Query Neighborhood Hits	288	Target Neighborhood Hits	242	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ARHG6_MOUSE
θ value	θ > 10 (rank : 300)	NC score	0.078845 (rank : 109)
Query Neighborhood Hits	288	Target Neighborhood Hits	394	Shared Neighborhood Hits	55
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

ARHGF_HUMAN
θ value	θ > 10 (rank : 301)	NC score	0.086126 (rank : 83)
Query Neighborhood Hits	288	Target Neighborhood Hits	214	Shared Neighborhood Hits	36
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

ARHGG_HUMAN
θ value	θ > 10 (rank : 302)	NC score	0.073795 (rank : 135)
Query Neighborhood Hits	288	Target Neighborhood Hits	129	Shared Neighborhood Hits	30
SwissProt Accessions	Q5VV41, Q86TF0, Q99434	Gene names	ARHGEF16, NBR
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

ARH_HUMAN
θ value	θ > 10 (rank : 303)	NC score	0.080589 (rank : 100)
Query Neighborhood Hits	288	Target Neighborhood Hits	38	Shared Neighborhood Hits	8
SwissProt Accessions	Q5SW96, Q6TQS9, Q8N2Y0, Q9UFI9	Gene names	LDLRAP1, ARH
Domain Architecture	No domain graphic available
Description	Low density lipoprotein receptor adapter protein 1 (Autosomal recessive hypercholesterolemia protein).

ASPP1_MOUSE
θ value	θ > 10 (rank : 304)	NC score	0.054257 (rank : 269)
Query Neighborhood Hits	288	Target Neighborhood Hits	1244	Shared Neighborhood Hits	121
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ATN1_HUMAN
θ value	θ > 10 (rank : 305)	NC score	0.055911 (rank : 250)
Query Neighborhood Hits	288	Target Neighborhood Hits	676	Shared Neighborhood Hits	60
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

BASP_HUMAN
θ value	θ > 10 (rank : 306)	NC score	0.085433 (rank : 84)
Query Neighborhood Hits	288	Target Neighborhood Hits	321	Shared Neighborhood Hits	44
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BASP_MOUSE
θ value	θ > 10 (rank : 307)	NC score	0.086631 (rank : 81)
Query Neighborhood Hits	288	Target Neighborhood Hits	260	Shared Neighborhood Hits	40
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BAT2_HUMAN
θ value	θ > 10 (rank : 308)	NC score	0.070422 (rank : 150)
Query Neighborhood Hits	288	Target Neighborhood Hits	931	Shared Neighborhood Hits	119
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BCAR1_HUMAN
θ value	θ > 10 (rank : 309)	NC score	0.065728 (rank : 171)
Query Neighborhood Hits	288	Target Neighborhood Hits	554	Shared Neighborhood Hits	94
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

BCAR1_MOUSE
θ value	θ > 10 (rank : 310)	NC score	0.059708 (rank : 217)
Query Neighborhood Hits	288	Target Neighborhood Hits	438	Shared Neighborhood Hits	87
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

BCL9_HUMAN
θ value	θ > 10 (rank : 311)	NC score	0.061256 (rank : 206)
Query Neighborhood Hits	288	Target Neighborhood Hits	1008	Shared Neighborhood Hits	106
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

BCL9_MOUSE
θ value	θ > 10 (rank : 312)	NC score	0.060918 (rank : 210)
Query Neighborhood Hits	288	Target Neighborhood Hits	770	Shared Neighborhood Hits	101
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

CABIN_HUMAN
θ value	θ > 10 (rank : 313)	NC score	0.053236 (rank : 277)
Query Neighborhood Hits	288	Target Neighborhood Hits	490	Shared Neighborhood Hits	75
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

CAPON_HUMAN
θ value	θ > 10 (rank : 314)	NC score	0.075888 (rank : 125)
Query Neighborhood Hits	288	Target Neighborhood Hits	35	Shared Neighborhood Hits	7
SwissProt Accessions	O75052, O43564	Gene names	NOS1AP, CAPON, KIAA0464
Domain Architecture	No domain graphic available
Description	Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (C--terminal PDZ ligand of neuronal nitric oxide synthase protein) (Nitric oxide synthase 1 adaptor protein).

CAPON_MOUSE
θ value	θ > 10 (rank : 315)	NC score	0.072277 (rank : 144)
Query Neighborhood Hits	288	Target Neighborhood Hits	34	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D3A8, Q80TZ6	Gene names	Nos1ap, Capon, Kiaa0464
Domain Architecture	No domain graphic available
Description	Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (C--terminal PDZ ligand of neuronal nitric oxide synthase protein) (Nitric oxide synthase 1 adaptor protein).

CCNK_MOUSE
θ value	θ > 10 (rank : 316)	NC score	0.056512 (rank : 247)
Query Neighborhood Hits	288	Target Neighborhood Hits	350	Shared Neighborhood Hits	33
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

CD2AP_MOUSE
θ value	θ > 10 (rank : 317)	NC score	0.111132 (rank : 35)
Query Neighborhood Hits	288	Target Neighborhood Hits	336	Shared Neighborhood Hits	70
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

CGRE1_HUMAN
θ value	θ > 10 (rank : 318)	NC score	0.052487 (rank : 285)
Query Neighborhood Hits	288	Target Neighborhood Hits	354	Shared Neighborhood Hits	57
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

CJ078_MOUSE
θ value	θ > 10 (rank : 319)	NC score	0.051529 (rank : 301)
Query Neighborhood Hits	288	Target Neighborhood Hits	559	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

CN155_HUMAN
θ value	θ > 10 (rank : 320)	NC score	0.070671 (rank : 148)
Query Neighborhood Hits	288	Target Neighborhood Hits	385	Shared Neighborhood Hits	45
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

CO1A2_HUMAN
θ value	θ > 10 (rank : 321)	NC score	0.058345 (rank : 234)
Query Neighborhood Hits	288	Target Neighborhood Hits	329	Shared Neighborhood Hits	53
SwissProt Accessions	P08123, P02464, Q9UEB6, Q9UPH0	Gene names	COL1A2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

CO1A2_MOUSE
θ value	θ > 10 (rank : 322)	NC score	0.061246 (rank : 207)
Query Neighborhood Hits	288	Target Neighborhood Hits	388	Shared Neighborhood Hits	59
SwissProt Accessions	Q01149, Q8CGA5	Gene names	Col1a2, Cola2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

CO2A1_HUMAN
θ value	θ > 10 (rank : 323)	NC score	0.066680 (rank : 165)
Query Neighborhood Hits	288	Target Neighborhood Hits	486	Shared Neighborhood Hits	79
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CO2A1_MOUSE
θ value	θ > 10 (rank : 324)	NC score	0.062677 (rank : 197)
Query Neighborhood Hits	288	Target Neighborhood Hits	483	Shared Neighborhood Hits	71
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CO4A1_HUMAN
θ value	θ > 10 (rank : 325)	NC score	0.059168 (rank : 222)
Query Neighborhood Hits	288	Target Neighborhood Hits	425	Shared Neighborhood Hits	64
SwissProt Accessions	P02462	Gene names	COL4A1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

CO4A1_MOUSE
θ value	θ > 10 (rank : 326)	NC score	0.060443 (rank : 213)
Query Neighborhood Hits	288	Target Neighborhood Hits	450	Shared Neighborhood Hits	73
SwissProt Accessions	P02463	Gene names	Col4a1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

CO4A2_HUMAN
θ value	θ > 10 (rank : 327)	NC score	0.056296 (rank : 249)
Query Neighborhood Hits	288	Target Neighborhood Hits	454	Shared Neighborhood Hits	68
SwissProt Accessions	P08572	Gene names	COL4A2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

CO4A2_MOUSE
θ value	θ > 10 (rank : 328)	NC score	0.057754 (rank : 239)
Query Neighborhood Hits	288	Target Neighborhood Hits	492	Shared Neighborhood Hits	72
SwissProt Accessions	P08122, Q61375	Gene names	Col4a2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

CO4A3_HUMAN
θ value	θ > 10 (rank : 329)	NC score	0.054939 (rank : 260)
Query Neighborhood Hits	288	Target Neighborhood Hits	421	Shared Neighborhood Hits	56
SwissProt Accessions	Q01955, Q9BQT2	Gene names	COL4A3
Domain Architecture
Description	Collagen alpha-3(IV) chain precursor (Goodpasture antigen).

CO4A4_HUMAN
θ value	θ > 10 (rank : 330)	NC score	0.058048 (rank : 236)
Query Neighborhood Hits	288	Target Neighborhood Hits	440	Shared Neighborhood Hits	68
SwissProt Accessions	P53420	Gene names	COL4A4
Domain Architecture
Description	Collagen alpha-4(IV) chain precursor.

CO5A3_HUMAN
θ value	θ > 10 (rank : 331)	NC score	0.060272 (rank : 214)
Query Neighborhood Hits	288	Target Neighborhood Hits	433	Shared Neighborhood Hits	74
SwissProt Accessions	P25940, Q9NZQ6	Gene names	COL5A3
Domain Architecture
Description	Collagen alpha-3(V) chain precursor.

CO6A1_HUMAN
θ value	θ > 10 (rank : 332)	NC score	0.051287 (rank : 303)
Query Neighborhood Hits	288	Target Neighborhood Hits	264	Shared Neighborhood Hits	47
SwissProt Accessions	P12109, O00117, O00118, Q14040, Q14041, Q16258	Gene names	COL6A1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

CO9A1_HUMAN
θ value	θ > 10 (rank : 333)	NC score	0.054067 (rank : 271)
Query Neighborhood Hits	288	Target Neighborhood Hits	420	Shared Neighborhood Hits	66
SwissProt Accessions	P20849, Q13699, Q13700, Q5TF52, Q6P467, Q96BM8, Q99225, Q9H151, Q9H152, Q9Y6P2, Q9Y6P3	Gene names	COL9A1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

CO9A1_MOUSE
θ value	θ > 10 (rank : 334)	NC score	0.054819 (rank : 263)
Query Neighborhood Hits	288	Target Neighborhood Hits	477	Shared Neighborhood Hits	76
SwissProt Accessions	Q05722, Q61269, Q61270, Q61433, Q61940	Gene names	Col9a1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

CO9A2_HUMAN
θ value	θ > 10 (rank : 335)	NC score	0.053916 (rank : 273)
Query Neighborhood Hits	288	Target Neighborhood Hits	261	Shared Neighborhood Hits	48
SwissProt Accessions	Q14055	Gene names	COL9A2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(IX) chain precursor.

CO9A2_MOUSE
θ value	θ > 10 (rank : 336)	NC score	0.054981 (rank : 258)
Query Neighborhood Hits	288	Target Neighborhood Hits	279	Shared Neighborhood Hits	45
SwissProt Accessions	Q07643	Gene names	Col9a2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(IX) chain precursor.

COBA1_MOUSE
θ value	θ > 10 (rank : 337)	NC score	0.058578 (rank : 231)
Query Neighborhood Hits	288	Target Neighborhood Hits	487	Shared Neighborhood Hits	73
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

COBA2_HUMAN
θ value	θ > 10 (rank : 338)	NC score	0.058348 (rank : 233)
Query Neighborhood Hits	288	Target Neighborhood Hits	408	Shared Neighborhood Hits	62
SwissProt Accessions	P13942, Q07751, Q13271, Q13272, Q13273, Q99866, Q9UIP9	Gene names	COL11A2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

COBA2_MOUSE
θ value	θ > 10 (rank : 339)	NC score	0.057447 (rank : 241)
Query Neighborhood Hits	288	Target Neighborhood Hits	501	Shared Neighborhood Hits	78
SwissProt Accessions	Q64739, Q61432, Q9Z1W0	Gene names	Col11a2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

COFA1_HUMAN
θ value	θ > 10 (rank : 340)	NC score	0.054251 (rank : 270)
Query Neighborhood Hits	288	Target Neighborhood Hits	292	Shared Neighborhood Hits	55
SwissProt Accessions	P39059, Q5T6J4, Q9Y4W4	Gene names	COL15A1
Domain Architecture
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV) (Restin) (Related to endostatin)].

COHA1_HUMAN
θ value	θ > 10 (rank : 341)	NC score	0.052116 (rank : 292)
Query Neighborhood Hits	288	Target Neighborhood Hits	400	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

COJA1_HUMAN
θ value	θ > 10 (rank : 342)	NC score	0.053868 (rank : 274)
Query Neighborhood Hits	288	Target Neighborhood Hits	323	Shared Neighborhood Hits	50
SwissProt Accessions	Q14993, Q00559, Q05850, Q12885, Q13676, Q5JUF0, Q5T424, Q9H572, Q9NPZ2, Q9NQP2	Gene names	COL19A1
Domain Architecture
Description	Collagen alpha-1(XIX) chain precursor (Collagen alpha-1(Y) chain).

CONA1_HUMAN
θ value	θ > 10 (rank : 343)	NC score	0.055383 (rank : 254)
Query Neighborhood Hits	288	Target Neighborhood Hits	281	Shared Neighborhood Hits	53
SwissProt Accessions	Q86Y22, Q8IVR4, Q9NT93	Gene names	COL23A1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

CONA1_MOUSE
θ value	θ > 10 (rank : 344)	NC score	0.051370 (rank : 302)
Query Neighborhood Hits	288	Target Neighborhood Hits	254	Shared Neighborhood Hits	52
SwissProt Accessions	Q8K4G2, Q5SUQ0	Gene names	Col23a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

CRKL_HUMAN
θ value	θ > 10 (rank : 345)	NC score	0.064522 (rank : 178)
Query Neighborhood Hits	288	Target Neighborhood Hits	313	Shared Neighborhood Hits	57
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

CRKL_MOUSE
θ value	θ > 10 (rank : 346)	NC score	0.064061 (rank : 182)
Query Neighborhood Hits	288	Target Neighborhood Hits	307	Shared Neighborhood Hits	57
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

CRK_HUMAN
θ value	θ > 10 (rank : 347)	NC score	0.075863 (rank : 126)
Query Neighborhood Hits	288	Target Neighborhood Hits	308	Shared Neighborhood Hits	59
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CRK_MOUSE
θ value	θ > 10 (rank : 348)	NC score	0.078549 (rank : 112)
Query Neighborhood Hits	288	Target Neighborhood Hits	314	Shared Neighborhood Hits	61
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CT032_HUMAN
θ value	θ > 10 (rank : 349)	NC score	0.050230 (rank : 307)
Query Neighborhood Hits	288	Target Neighborhood Hits	235	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

DBNL_HUMAN
θ value	θ > 10 (rank : 350)	NC score	0.068278 (rank : 162)
Query Neighborhood Hits	288	Target Neighborhood Hits	244	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UJU6, P84070, Q6IAI8, Q96F30, Q96K74, Q9HBN8, Q9NR72	Gene names	DBNL, CMAP, SH3P7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein).

DBNL_MOUSE
θ value	θ > 10 (rank : 351)	NC score	0.066500 (rank : 167)
Query Neighborhood Hits	288	Target Neighborhood Hits	306	Shared Neighborhood Hits	52
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

DDEF1_MOUSE
θ value	θ > 10 (rank : 352)	NC score	0.078700 (rank : 111)
Query Neighborhood Hits	288	Target Neighborhood Hits	592	Shared Neighborhood Hits	83
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

DIDO1_HUMAN
θ value	θ > 10 (rank : 353)	NC score	0.066531 (rank : 166)
Query Neighborhood Hits	288	Target Neighborhood Hits	960	Shared Neighborhood Hits	115
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

EFS_HUMAN
θ value	θ > 10 (rank : 354)	NC score	0.087175 (rank : 80)
Query Neighborhood Hits	288	Target Neighborhood Hits	348	Shared Neighborhood Hits	74
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

EFS_MOUSE
θ value	θ > 10 (rank : 355)	NC score	0.080085 (rank : 103)
Query Neighborhood Hits	288	Target Neighborhood Hits	389	Shared Neighborhood Hits	83
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

ENAH_MOUSE
θ value	θ > 10 (rank : 356)	NC score	0.059435 (rank : 220)
Query Neighborhood Hits	288	Target Neighborhood Hits	919	Shared Neighborhood Hits	69
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

FYB_HUMAN
θ value	θ > 10 (rank : 357)	NC score	0.050951 (rank : 305)
Query Neighborhood Hits	288	Target Neighborhood Hits	379	Shared Neighborhood Hits	63
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

GGN_HUMAN
θ value	θ > 10 (rank : 358)	NC score	0.063602 (rank : 187)
Query Neighborhood Hits	288	Target Neighborhood Hits	269	Shared Neighborhood Hits	33
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GRAP2_HUMAN
θ value	θ > 10 (rank : 359)	NC score	0.057349 (rank : 242)
Query Neighborhood Hits	288	Target Neighborhood Hits	304	Shared Neighborhood Hits	56
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

GRAP2_MOUSE
θ value	θ > 10 (rank : 360)	NC score	0.060991 (rank : 208)
Query Neighborhood Hits	288	Target Neighborhood Hits	297	Shared Neighborhood Hits	58
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

GRAP_HUMAN
θ value	θ > 10 (rank : 361)	NC score	0.061962 (rank : 201)
Query Neighborhood Hits	288	Target Neighborhood Hits	307	Shared Neighborhood Hits	62
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

GRB2_HUMAN
θ value	θ > 10 (rank : 362)	NC score	0.064694 (rank : 177)
Query Neighborhood Hits	288	Target Neighborhood Hits	310	Shared Neighborhood Hits	58
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
θ value	θ > 10 (rank : 363)	NC score	0.064238 (rank : 181)
Query Neighborhood Hits	288	Target Neighborhood Hits	312	Shared Neighborhood Hits	58
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

GRIN1_MOUSE
θ value	θ > 10 (rank : 364)	NC score	0.060146 (rank : 216)
Query Neighborhood Hits	288	Target Neighborhood Hits	337	Shared Neighborhood Hits	36
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

HCLS1_HUMAN
θ value	θ > 10 (rank : 365)	NC score	0.085326 (rank : 85)
Query Neighborhood Hits	288	Target Neighborhood Hits	358	Shared Neighborhood Hits	73
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

HCLS1_MOUSE
θ value	θ > 10 (rank : 366)	NC score	0.087677 (rank : 76)
Query Neighborhood Hits	288	Target Neighborhood Hits	329	Shared Neighborhood Hits	71
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

IASPP_MOUSE
θ value	θ > 10 (rank : 367)	NC score	0.063405 (rank : 190)
Query Neighborhood Hits	288	Target Neighborhood Hits	1024	Shared Neighborhood Hits	141
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

ITSN2_HUMAN
θ value	θ > 10 (rank : 368)	NC score	0.073620 (rank : 136)
Query Neighborhood Hits	288	Target Neighborhood Hits	1173	Shared Neighborhood Hits	79
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

ITSN2_MOUSE
θ value	θ > 10 (rank : 369)	NC score	0.069798 (rank : 153)
Query Neighborhood Hits	288	Target Neighborhood Hits	1371	Shared Neighborhood Hits	80
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

MAGE1_HUMAN
θ value	θ > 10 (rank : 370)	NC score	0.067723 (rank : 163)
Query Neighborhood Hits	288	Target Neighborhood Hits	1389	Shared Neighborhood Hits	139
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MARCS_HUMAN
θ value	θ > 10 (rank : 371)	NC score	0.077544 (rank : 118)
Query Neighborhood Hits	288	Target Neighborhood Hits	204	Shared Neighborhood Hits	30
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

MARCS_MOUSE
θ value	θ > 10 (rank : 372)	NC score	0.072605 (rank : 143)
Query Neighborhood Hits	288	Target Neighborhood Hits	227	Shared Neighborhood Hits	33
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

MBD6_HUMAN
θ value	θ > 10 (rank : 373)	NC score	0.065992 (rank : 168)
Query Neighborhood Hits	288	Target Neighborhood Hits	349	Shared Neighborhood Hits	45
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

MDC1_HUMAN
θ value	θ > 10 (rank : 374)	NC score	0.051880 (rank : 296)
Query Neighborhood Hits	288	Target Neighborhood Hits	1446	Shared Neighborhood Hits	97
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MUC1_HUMAN
θ value	θ > 10 (rank : 375)	NC score	0.079068 (rank : 107)
Query Neighborhood Hits	288	Target Neighborhood Hits	975	Shared Neighborhood Hits	110
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

MUC7_HUMAN
θ value	θ > 10 (rank : 376)	NC score	0.103746 (rank : 47)
Query Neighborhood Hits	288	Target Neighborhood Hits	538	Shared Neighborhood Hits	64
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

NACAM_MOUSE
θ value	θ > 10 (rank : 377)	NC score	0.069723 (rank : 155)
Query Neighborhood Hits	288	Target Neighborhood Hits	1866	Shared Neighborhood Hits	136
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NCF1_HUMAN
θ value	θ > 10 (rank : 378)	NC score	0.070245 (rank : 151)
Query Neighborhood Hits	288	Target Neighborhood Hits	198	Shared Neighborhood Hits	46
SwissProt Accessions	P14598, O43842, Q2PP07, Q9BU90, Q9BXI7, Q9BXI8, Q9UDV9, Q9UMU2	Gene names	NCF1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDa autosomal chronic granulomatous disease protein) (NOXO2).

NCF1_MOUSE
θ value	θ > 10 (rank : 379)	NC score	0.068543 (rank : 161)
Query Neighborhood Hits	288	Target Neighborhood Hits	198	Shared Neighborhood Hits	43
SwissProt Accessions	Q09014, O70144, Q9JI34	Gene names	Ncf1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K).

NCF4_HUMAN
θ value	θ > 10 (rank : 380)	NC score	0.076147 (rank : 122)
Query Neighborhood Hits	288	Target Neighborhood Hits	161	Shared Neighborhood Hits	42
SwissProt Accessions	Q15080, O60808, Q86U56, Q9BU98, Q9NP45	Gene names	NCF4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

NCF4_MOUSE
θ value	θ > 10 (rank : 381)	NC score	0.078536 (rank : 113)
Query Neighborhood Hits	288	Target Neighborhood Hits	177	Shared Neighborhood Hits	47
SwissProt Accessions	P97369	Gene names	Ncf4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

NCK1_HUMAN
θ value	θ > 10 (rank : 382)	NC score	0.069762 (rank : 154)
Query Neighborhood Hits	288	Target Neighborhood Hits	312	Shared Neighborhood Hits	59
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

NCK2_HUMAN
θ value	θ > 10 (rank : 383)	NC score	0.070119 (rank : 152)
Query Neighborhood Hits	288	Target Neighborhood Hits	310	Shared Neighborhood Hits	62
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

NEBU_HUMAN
θ value	θ > 10 (rank : 384)	NC score	0.079959 (rank : 104)
Query Neighborhood Hits	288	Target Neighborhood Hits	420	Shared Neighborhood Hits	62
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

NOLC1_HUMAN
θ value	θ > 10 (rank : 385)	NC score	0.050028 (rank : 310)
Query Neighborhood Hits	288	Target Neighborhood Hits	452	Shared Neighborhood Hits	36
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

NUMBL_HUMAN
θ value	θ > 10 (rank : 386)	NC score	0.078180 (rank : 117)
Query Neighborhood Hits	288	Target Neighborhood Hits	394	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

NUMBL_MOUSE
θ value	θ > 10 (rank : 387)	NC score	0.068726 (rank : 158)
Query Neighborhood Hits	288	Target Neighborhood Hits	147	Shared Neighborhood Hits	20
SwissProt Accessions	O08919, Q6NVG8	Gene names	Numbl, Nbl
Domain Architecture
Description	Numb-like protein.

NUMB_HUMAN
θ value	θ > 10 (rank : 388)	NC score	0.054294 (rank : 268)
Query Neighborhood Hits	288	Target Neighborhood Hits	112	Shared Neighborhood Hits	13
SwissProt Accessions	P49757, Q6NUQ7, Q86SY1, Q8WW73, Q9UBG1, Q9UEQ4, Q9UKE8, Q9UKE9, Q9UKF0, Q9UQJ4	Gene names	NUMB
Domain Architecture
Description	Protein numb homolog (h-Numb) (Protein S171).

NUMB_MOUSE
θ value	θ > 10 (rank : 389)	NC score	0.052572 (rank : 284)
Query Neighborhood Hits	288	Target Neighborhood Hits	91	Shared Neighborhood Hits	12
SwissProt Accessions	Q9QZS3, P70422, Q8CIB1, Q9DC57, Q9QZR1, Q9QZS4	Gene names	Numb
Domain Architecture
Description	Protein numb homolog (m-Numb) (m-Nb).

OGFR_MOUSE
θ value	θ > 10 (rank : 390)	NC score	0.078340 (rank : 116)
Query Neighborhood Hits	288	Target Neighborhood Hits	584	Shared Neighborhood Hits	73
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

PCLO_HUMAN
θ value	θ > 10 (rank : 391)	NC score	0.075557 (rank : 128)
Query Neighborhood Hits	288	Target Neighborhood Hits	2046	Shared Neighborhood Hits	137
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PELP1_HUMAN
θ value	θ > 10 (rank : 392)	NC score	0.054961 (rank : 259)
Query Neighborhood Hits	288	Target Neighborhood Hits	596	Shared Neighborhood Hits	62
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

PELP1_MOUSE
θ value	θ > 10 (rank : 393)	NC score	0.059465 (rank : 219)
Query Neighborhood Hits	288	Target Neighborhood Hits	709	Shared Neighborhood Hits	94
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

PEX13_MOUSE
θ value	θ > 10 (rank : 394)	NC score	0.052617 (rank : 282)
Query Neighborhood Hits	288	Target Neighborhood Hits	126	Shared Neighborhood Hits	36
SwissProt Accessions	Q9D0K1, Q3U5T1, Q8CCJ5, Q8CCW5, Q99MM2, Q9EPK1	Gene names	Pex13
Domain Architecture	No domain graphic available
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

PRG4_HUMAN
θ value	θ > 10 (rank : 395)	NC score	0.052119 (rank : 291)
Query Neighborhood Hits	288	Target Neighborhood Hits	764	Shared Neighborhood Hits	62
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRR12_HUMAN
θ value	θ > 10 (rank : 396)	NC score	0.065353 (rank : 173)
Query Neighborhood Hits	288	Target Neighborhood Hits	460	Shared Neighborhood Hits	52
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

RIMB1_HUMAN
θ value	θ > 10 (rank : 397)	NC score	0.065688 (rank : 172)
Query Neighborhood Hits	288	Target Neighborhood Hits	1479	Shared Neighborhood Hits	124
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RIMB2_HUMAN
θ value	θ > 10 (rank : 398)	NC score	0.055342 (rank : 255)
Query Neighborhood Hits	288	Target Neighborhood Hits	263	Shared Neighborhood Hits	52
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

RIMB2_MOUSE
θ value	θ > 10 (rank : 399)	NC score	0.052323 (rank : 288)
Query Neighborhood Hits	288	Target Neighborhood Hits	246	Shared Neighborhood Hits	44
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

SC24C_HUMAN
θ value	θ > 10 (rank : 400)	NC score	0.056322 (rank : 248)
Query Neighborhood Hits	288	Target Neighborhood Hits	662	Shared Neighborhood Hits	87
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

SET1A_HUMAN
θ value	θ > 10 (rank : 401)	NC score	0.055590 (rank : 251)
Query Neighborhood Hits	288	Target Neighborhood Hits	690	Shared Neighborhood Hits	61
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SGIP1_MOUSE
θ value	θ > 10 (rank : 402)	NC score	0.052578 (rank : 283)
Query Neighborhood Hits	288	Target Neighborhood Hits	180	Shared Neighborhood Hits	35
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SH3G1_HUMAN
θ value	θ > 10 (rank : 403)	NC score	0.085054 (rank : 87)
Query Neighborhood Hits	288	Target Neighborhood Hits	307	Shared Neighborhood Hits	59
SwissProt Accessions	Q99961, Q99668	Gene names	SH3GL1, CNSA1, SH3D2B
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL).

SH3G1_MOUSE
θ value	θ > 10 (rank : 404)	NC score	0.082076 (rank : 95)
Query Neighborhood Hits	288	Target Neighborhood Hits	291	Shared Neighborhood Hits	54
SwissProt Accessions	Q62419	Gene names	Sh3gl1, Sh3d2b
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (SH3p8).

SH3G2_HUMAN
θ value	θ > 10 (rank : 405)	NC score	0.087664 (rank : 77)
Query Neighborhood Hits	288	Target Neighborhood Hits	324	Shared Neighborhood Hits	57
SwissProt Accessions	Q99962, Q9NQK5	Gene names	SH3GL2, CNSA2, SH3D2A
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (EEN-B1).

SH3G2_MOUSE
θ value	θ > 10 (rank : 406)	NC score	0.084400 (rank : 90)
Query Neighborhood Hits	288	Target Neighborhood Hits	319	Shared Neighborhood Hits	57
SwissProt Accessions	Q62420	Gene names	Sh3gl2, Sh3d2a
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (SH3p4).

SH3G3_HUMAN
θ value	θ > 10 (rank : 407)	NC score	0.085209 (rank : 86)
Query Neighborhood Hits	288	Target Neighborhood Hits	222	Shared Neighborhood Hits	51
SwissProt Accessions	Q99963, O43553, O43554	Gene names	SH3GL3, CNSA3, SH3D2C
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (EEN-B2).

SH3G3_MOUSE
θ value	θ > 10 (rank : 408)	NC score	0.089048 (rank : 69)
Query Neighborhood Hits	288	Target Neighborhood Hits	236	Shared Neighborhood Hits	52
SwissProt Accessions	Q62421	Gene names	Sh3gl3, Sh3d2c, Sh3d2c2
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (SH3p13).

SNX9_MOUSE
θ value	θ > 10 (rank : 409)	NC score	0.059642 (rank : 218)
Query Neighborhood Hits	288	Target Neighborhood Hits	141	Shared Neighborhood Hits	35
SwissProt Accessions	Q91VH2	Gene names	Snx9
Domain Architecture
Description	Sorting nexin-9.

SON_HUMAN
θ value	θ > 10 (rank : 410)	NC score	0.078810 (rank : 110)
Query Neighborhood Hits	288	Target Neighborhood Hits	1568	Shared Neighborhood Hits	142
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

SON_MOUSE
θ value	θ > 10 (rank : 411)	NC score	0.062808 (rank : 194)
Query Neighborhood Hits	288	Target Neighborhood Hits	957	Shared Neighborhood Hits	94
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

SRRM1_HUMAN
θ value	θ > 10 (rank : 412)	NC score	0.089061 (rank : 68)
Query Neighborhood Hits	288	Target Neighborhood Hits	690	Shared Neighborhood Hits	70
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SRRM1_MOUSE
θ value	θ > 10 (rank : 413)	NC score	0.101435 (rank : 48)
Query Neighborhood Hits	288	Target Neighborhood Hits	966	Shared Neighborhood Hits	101
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SRRM2_HUMAN
θ value	θ > 10 (rank : 414)	NC score	0.059063 (rank : 225)
Query Neighborhood Hits	288	Target Neighborhood Hits	1296	Shared Neighborhood Hits	89
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SRRM2_MOUSE
θ value	θ > 10 (rank : 415)	NC score	0.081283 (rank : 97)
Query Neighborhood Hits	288	Target Neighborhood Hits	1470	Shared Neighborhood Hits	102
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

SSBP4_HUMAN
θ value	θ > 10 (rank : 416)	NC score	0.053339 (rank : 276)
Query Neighborhood Hits	288	Target Neighborhood Hits	753	Shared Neighborhood Hits	98
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

STAC3_HUMAN
θ value	θ > 10 (rank : 417)	NC score	0.054834 (rank : 262)
Query Neighborhood Hits	288	Target Neighborhood Hits	228	Shared Neighborhood Hits	43
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC3_MOUSE
θ value	θ > 10 (rank : 418)	NC score	0.054919 (rank : 261)
Query Neighborhood Hits	288	Target Neighborhood Hits	232	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAM1_HUMAN
θ value	θ > 10 (rank : 419)	NC score	0.065172 (rank : 175)
Query Neighborhood Hits	288	Target Neighborhood Hits	271	Shared Neighborhood Hits	54
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAM1_MOUSE
θ value	θ > 10 (rank : 420)	NC score	0.065766 (rank : 170)
Query Neighborhood Hits	288	Target Neighborhood Hits	273	Shared Neighborhood Hits	54
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAM2_HUMAN
θ value	θ > 10 (rank : 421)	NC score	0.062498 (rank : 200)
Query Neighborhood Hits	288	Target Neighborhood Hits	288	Shared Neighborhood Hits	56
SwissProt Accessions	O75886, Q7LDQ0, Q9UF58	Gene names	STAM2
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2).

STAM2_MOUSE
θ value	θ > 10 (rank : 422)	NC score	0.063767 (rank : 184)
Query Neighborhood Hits	288	Target Neighborhood Hits	285	Shared Neighborhood Hits	52
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

STS1_HUMAN
θ value	θ > 10 (rank : 423)	NC score	0.083820 (rank : 91)
Query Neighborhood Hits	288	Target Neighborhood Hits	106	Shared Neighborhood Hits	41
SwissProt Accessions	Q8TF42, Q53GT5, Q53GT8, Q8NBV7, Q96IG9, Q96NZ2	Gene names	STS1, KIAA1959
Domain Architecture	No domain graphic available
Description	Suppressor of T-cell receptor signaling 1 (Sts-1) (Cbl-interacting protein p70).

STS1_MOUSE
θ value	θ > 10 (rank : 424)	NC score	0.080994 (rank : 99)
Query Neighborhood Hits	288	Target Neighborhood Hits	104	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BGG7, Q3U8Z2, Q8BMW9	Gene names	Sts1
Domain Architecture	No domain graphic available
Description	Suppressor of T-cell receptor signaling 1 (Sts-1) (Cbl-interacting protein p70).

SYN1_HUMAN
θ value	θ > 10 (rank : 425)	NC score	0.077053 (rank : 120)
Query Neighborhood Hits	288	Target Neighborhood Hits	419	Shared Neighborhood Hits	53
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

SYN1_MOUSE
θ value	θ > 10 (rank : 426)	NC score	0.056940 (rank : 245)
Query Neighborhood Hits	288	Target Neighborhood Hits	363	Shared Neighborhood Hits	41
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

TAU_HUMAN
θ value	θ > 10 (rank : 427)	NC score	0.053968 (rank : 272)
Query Neighborhood Hits	288	Target Neighborhood Hits	448	Shared Neighborhood Hits	66
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TCGAP_HUMAN
θ value	θ > 10 (rank : 428)	NC score	0.058592 (rank : 230)
Query Neighborhood Hits	288	Target Neighborhood Hits	872	Shared Neighborhood Hits	137
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TCOF_HUMAN
θ value	θ > 10 (rank : 429)	NC score	0.051630 (rank : 298)
Query Neighborhood Hits	288	Target Neighborhood Hits	543	Shared Neighborhood Hits	53
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

TCOF_MOUSE
θ value	θ > 10 (rank : 430)	NC score	0.055408 (rank : 253)
Query Neighborhood Hits	288	Target Neighborhood Hits	471	Shared Neighborhood Hits	52
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

TMAP1_HUMAN
θ value	θ > 10 (rank : 431)	NC score	0.082149 (rank : 93)
Query Neighborhood Hits	288	Target Neighborhood Hits	140	Shared Neighborhood Hits	31
SwissProt Accessions	P84157	Gene names	TMAP1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

VAV2_HUMAN
θ value	θ > 10 (rank : 432)	NC score	0.063441 (rank : 189)
Query Neighborhood Hits	288	Target Neighborhood Hits	453	Shared Neighborhood Hits	60
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

VAV2_MOUSE
θ value	θ > 10 (rank : 433)	NC score	0.064373 (rank : 180)
Query Neighborhood Hits	288	Target Neighborhood Hits	456	Shared Neighborhood Hits	66
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

VAV3_HUMAN
θ value	θ > 10 (rank : 434)	NC score	0.052807 (rank : 280)
Query Neighborhood Hits	288	Target Neighborhood Hits	398	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

VAV3_MOUSE
θ value	θ > 10 (rank : 435)	NC score	0.053127 (rank : 279)
Query Neighborhood Hits	288	Target Neighborhood Hits	404	Shared Neighborhood Hits	58
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

VAV_HUMAN
θ value	θ > 10 (rank : 436)	NC score	0.065908 (rank : 169)
Query Neighborhood Hits	288	Target Neighborhood Hits	452	Shared Neighborhood Hits	62
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

VCX3_HUMAN
θ value	θ > 10 (rank : 437)	NC score	0.054557 (rank : 265)
Query Neighborhood Hits	288	Target Neighborhood Hits	105	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NNX9, Q9P0H4	Gene names	VCX3A, VCX3, VCX8R, VCXA
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 3 (VCX-A protein) (Variably charged protein X-A) (Variable charge protein on X with eight repeats) (VCX- 8r).

VCY1_HUMAN
θ value	θ > 10 (rank : 438)	NC score	0.051552 (rank : 299)
Query Neighborhood Hits	288	Target Neighborhood Hits	38	Shared Neighborhood Hits	7
SwissProt Accessions	O14598	Gene names	VCY, BPY1
Domain Architecture	No domain graphic available
Description	Testis-specific basic protein Y 1 (Variably charged protein Y).

WASIP_HUMAN
θ value	θ > 10 (rank : 439)	NC score	0.088613 (rank : 73)
Query Neighborhood Hits	288	Target Neighborhood Hits	458	Shared Neighborhood Hits	49
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

WIRE_MOUSE
θ value	θ > 10 (rank : 440)	NC score	0.058633 (rank : 229)
Query Neighborhood Hits	288	Target Neighborhood Hits	310	Shared Neighborhood Hits	44
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

YLPM1_HUMAN
θ value	θ > 10 (rank : 441)	NC score	0.054508 (rank : 266)
Query Neighborhood Hits	288	Target Neighborhood Hits	670	Shared Neighborhood Hits	71
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

ZN385_HUMAN
θ value	θ > 10 (rank : 442)	NC score	0.058729 (rank : 228)
Query Neighborhood Hits	288	Target Neighborhood Hits	614	Shared Neighborhood Hits	93
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

Hits sorted by NC score

JIP2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	288	Target Neighborhood Hits	288	Shared Neighborhood Hits	288
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

JIP2_MOUSE
NC score	0.941773 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	288	Target Neighborhood Hits	144	Shared Neighborhood Hits	99
SwissProt Accessions	Q9ERE9, Q9CXI4	Gene names	Mapk8ip2, Ib2, Jip2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

JIP1_HUMAN
NC score	0.837558 (rank : 3)	θ value	1.94955e-95 (rank : 3)
Query Neighborhood Hits	288	Target Neighborhood Hits	271	Shared Neighborhood Hits	89
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

JIP1_MOUSE
NC score	0.830408 (rank : 4)	θ value	3.32542e-95 (rank : 4)
Query Neighborhood Hits	288	Target Neighborhood Hits	259	Shared Neighborhood Hits	81
SwissProt Accessions	Q9WVI9, O35145, Q925J8, Q9R1H9, Q9R1Z1, Q9WVI7, Q9WVI8	Gene names	Mapk8ip1, Ib1, Jip1, Mapk8ip, Prkm8ip
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain-1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

VINEX_HUMAN
NC score	0.248224 (rank : 5)	θ value	0.000270298 (rank : 7)
Query Neighborhood Hits	288	Target Neighborhood Hits	270	Shared Neighborhood Hits	68
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

VINEX_MOUSE
NC score	0.247830 (rank : 6)	θ value	0.00020696 (rank : 6)
Query Neighborhood Hits	288	Target Neighborhood Hits	286	Shared Neighborhood Hits	67
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

SRBS1_HUMAN
NC score	0.239997 (rank : 7)	θ value	0.000461057 (rank : 8)
Query Neighborhood Hits	288	Target Neighborhood Hits	396	Shared Neighborhood Hits	81
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SRBS1_MOUSE
NC score	0.237216 (rank : 8)	θ value	0.000602161 (rank : 9)
Query Neighborhood Hits	288	Target Neighborhood Hits	409	Shared Neighborhood Hits	87
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

STS2_HUMAN
NC score	0.195372 (rank : 9)	θ value	0.00665767 (rank : 16)
Query Neighborhood Hits	288	Target Neighborhood Hits	108	Shared Neighborhood Hits	51
SwissProt Accessions	P57075, Q6HA34, Q6HA35, Q6ISI6, Q6ISK3, Q6ISS9	Gene names	UBASH3A, STS2
Domain Architecture
Description	Suppressor of T-cell receptor signaling 2 (STS-2) (Cbl-interacting protein 4) (CLIP4) (T-cell ubiquitin ligand) (TULA).

LASP1_MOUSE
NC score	0.170672 (rank : 10)	θ value	0.0330416 (rank : 25)
Query Neighborhood Hits	288	Target Neighborhood Hits	297	Shared Neighborhood Hits	64
SwissProt Accessions	Q61792, Q62416	Gene names	Lasp1, Mln50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

LASP1_HUMAN
NC score	0.170665 (rank : 11)	θ value	0.0330416 (rank : 24)
Query Neighborhood Hits	288	Target Neighborhood Hits	293	Shared Neighborhood Hits	64
SwissProt Accessions	Q14847, Q96ED2, Q96IG0	Gene names	LASP1, MLN50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

ARHG5_HUMAN
NC score	0.168716 (rank : 12)	θ value	0.00390308 (rank : 13)
Query Neighborhood Hits	288	Target Neighborhood Hits	172	Shared Neighborhood Hits	52
SwissProt Accessions	Q12774	Gene names	ARHGEF5, TIM
Domain Architecture
Description	Rho guanine nucleotide exchange factor 5 (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (p60 TIM) (Transforming immortalized mammary oncogene).

PPIP1_HUMAN
NC score	0.164894 (rank : 13)	θ value	0.0736092 (rank : 29)
Query Neighborhood Hits	288	Target Neighborhood Hits	389	Shared Neighborhood Hits	64
SwissProt Accessions	O43586, O43585, O95657	Gene names	PSTPIP1, CD2BP1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP).

CD2AP_HUMAN
NC score	0.156008 (rank : 14)	θ value	0.365318 (rank : 55)
Query Neighborhood Hits	288	Target Neighborhood Hits	315	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

PPIP1_MOUSE
NC score	0.155910 (rank : 15)	θ value	0.62314 (rank : 78)
Query Neighborhood Hits	288	Target Neighborhood Hits	377	Shared Neighborhood Hits	66
SwissProt Accessions	P97814, Q4V9R4	Gene names	Pstpip1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1).

NCF2_HUMAN
NC score	0.140690 (rank : 16)	θ value	2.36792 (rank : 145)
Query Neighborhood Hits	288	Target Neighborhood Hits	229	Shared Neighborhood Hits	56
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

DNMBP_HUMAN
NC score	0.138565 (rank : 17)	θ value	0.125558 (rank : 39)
Query Neighborhood Hits	288	Target Neighborhood Hits	413	Shared Neighborhood Hits	69
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

NEBL_HUMAN
NC score	0.136547 (rank : 18)	θ value	0.279714 (rank : 50)
Query Neighborhood Hits	288	Target Neighborhood Hits	457	Shared Neighborhood Hits	71
SwissProt Accessions	O76041, Q9UIC4	Gene names	NEBL
Domain Architecture
Description	Nebulette (Actin-binding Z-disk protein).

SH3K1_MOUSE
NC score	0.133629 (rank : 19)	θ value	0.62314 (rank : 79)
Query Neighborhood Hits	288	Target Neighborhood Hits	332	Shared Neighborhood Hits	70
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

SNX18_HUMAN
NC score	0.132035 (rank : 20)	θ value	0.0961366 (rank : 37)
Query Neighborhood Hits	288	Target Neighborhood Hits	207	Shared Neighborhood Hits	57
SwissProt Accessions	Q96RF0	Gene names	SNAG1, SNX18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

SNX18_MOUSE
NC score	0.131622 (rank : 21)	θ value	0.0736092 (rank : 33)
Query Neighborhood Hits	288	Target Neighborhood Hits	198	Shared Neighborhood Hits	53
SwissProt Accessions	Q91ZR2	Gene names	Snag1, Snx18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

DNMBP_MOUSE
NC score	0.131432 (rank : 22)	θ value	0.21417 (rank : 46)
Query Neighborhood Hits	288	Target Neighborhood Hits	435	Shared Neighborhood Hits	77
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

ARHGG_MOUSE
NC score	0.129775 (rank : 23)	θ value	0.00869519 (rank : 17)
Query Neighborhood Hits	288	Target Neighborhood Hits	152	Shared Neighborhood Hits	42
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

SH3K1_HUMAN
NC score	0.125903 (rank : 24)	θ value	8.99809 (rank : 278)
Query Neighborhood Hits	288	Target Neighborhood Hits	341	Shared Neighborhood Hits	68
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

OSTF1_HUMAN
NC score	0.124843 (rank : 25)	θ value	0.279714 (rank : 51)
Query Neighborhood Hits	288	Target Neighborhood Hits	466	Shared Neighborhood Hits	66
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

OSTF1_MOUSE
NC score	0.117899 (rank : 26)	θ value	0.47712 (rank : 67)
Query Neighborhood Hits	288	Target Neighborhood Hits	467	Shared Neighborhood Hits	66
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

NGEF_MOUSE
NC score	0.115928 (rank : 27)	θ value	0.21417 (rank : 47)
Query Neighborhood Hits	288	Target Neighborhood Hits	228	Shared Neighborhood Hits	51
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

RGS3_MOUSE
NC score	0.115661 (rank : 28)	θ value	0.0736092 (rank : 30)
Query Neighborhood Hits	288	Target Neighborhood Hits	1621	Shared Neighborhood Hits	151
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

DDEF2_HUMAN
NC score	0.114954 (rank : 29)	θ value	0.0113563 (rank : 18)
Query Neighborhood Hits	288	Target Neighborhood Hits	599	Shared Neighborhood Hits	94
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

OGFR_HUMAN
NC score	0.113882 (rank : 30)	θ value	0.0193708 (rank : 20)
Query Neighborhood Hits	288	Target Neighborhood Hits	1582	Shared Neighborhood Hits	155
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

PACN1_MOUSE
NC score	0.113543 (rank : 31)	θ value	1.38821 (rank : 110)
Query Neighborhood Hits	288	Target Neighborhood Hits	283	Shared Neighborhood Hits	60
SwissProt Accessions	Q61644	Gene names	Pacsin1, Pacsin
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

PACN1_HUMAN
NC score	0.113216 (rank : 32)	θ value	1.38821 (rank : 109)
Query Neighborhood Hits	288	Target Neighborhood Hits	320	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BY11, Q9P2G8	Gene names	PACSIN1, KIAA1379
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

DDEF2_MOUSE
NC score	0.112394 (rank : 33)	θ value	0.0330416 (rank : 23)
Query Neighborhood Hits	288	Target Neighborhood Hits	625	Shared Neighborhood Hits	90
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

NGEF_HUMAN
NC score	0.112274 (rank : 34)	θ value	0.0961366 (rank : 36)
Query Neighborhood Hits	288	Target Neighborhood Hits	166	Shared Neighborhood Hits	41
SwissProt Accessions	Q8N5V2, Q53QQ4, Q53ST7, Q6GMQ5, Q9NQD6	Gene names	NGEF
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

CD2AP_MOUSE
NC score	0.111132 (rank : 35)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	288	Target Neighborhood Hits	336	Shared Neighborhood Hits	70
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

PACN2_MOUSE
NC score	0.110760 (rank : 36)	θ value	1.06291 (rank : 97)
Query Neighborhood Hits	288	Target Neighborhood Hits	382	Shared Neighborhood Hits	63
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

PACN3_HUMAN
NC score	0.109614 (rank : 37)	θ value	3.0926 (rank : 168)
Query Neighborhood Hits	288	Target Neighborhood Hits	385	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UKS6, Q9H331, Q9NWV9	Gene names	PACSIN3
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) (Endophilin I).

ARH_MOUSE
NC score	0.108961 (rank : 38)	θ value	0.813845 (rank : 81)
Query Neighborhood Hits	288	Target Neighborhood Hits	32	Shared Neighborhood Hits	7
SwissProt Accessions	Q8C142, Q6NWV6, Q8VDQ0	Gene names	Ldlrap1, Arh
Domain Architecture	No domain graphic available
Description	Low density lipoprotein receptor adapter protein 1 (Autosomal recessive hypercholesterolemia protein homolog).

PACN3_MOUSE
NC score	0.108538 (rank : 39)	θ value	3.0926 (rank : 169)
Query Neighborhood Hits	288	Target Neighborhood Hits	380	Shared Neighborhood Hits	61
SwissProt Accessions	Q99JB8, Q9EQP9	Gene names	Pacsin3
Domain Architecture
Description	Protein kinase C and casein kinase II substrate protein 3.

GRIN1_HUMAN
NC score	0.108016 (rank : 40)	θ value	0.00509761 (rank : 14)
Query Neighborhood Hits	288	Target Neighborhood Hits	681	Shared Neighborhood Hits	84
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

SPN90_MOUSE
NC score	0.107717 (rank : 41)	θ value	0.125558 (rank : 41)
Query Neighborhood Hits	288	Target Neighborhood Hits	157	Shared Neighborhood Hits	35
SwissProt Accessions	Q9ESJ4, Q68G72	Gene names	Nckipsd, Spin90, Wasbp
Domain Architecture	No domain graphic available
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (N-WASP-interacting protein, 90kDa) (Wiskott-Aldrich syndrome protein-binding protein WISH) (N-WASP-binding protein).

STAC_MOUSE
NC score	0.107637 (rank : 42)	θ value	1.06291 (rank : 100)
Query Neighborhood Hits	288	Target Neighborhood Hits	268	Shared Neighborhood Hits	53
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

BSN_HUMAN
NC score	0.104954 (rank : 43)	θ value	0.62314 (rank : 71)
Query Neighborhood Hits	288	Target Neighborhood Hits	1537	Shared Neighborhood Hits	131
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

PACN2_HUMAN
NC score	0.104651 (rank : 44)	θ value	3.0926 (rank : 167)
Query Neighborhood Hits	288	Target Neighborhood Hits	339	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UNF0, O95921, Q96HV9, Q9H0D3, Q9NPN1, Q9Y4V2	Gene names	PACSIN2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

BSN_MOUSE
NC score	0.104608 (rank : 45)	θ value	2.36792 (rank : 132)
Query Neighborhood Hits	288	Target Neighborhood Hits	2057	Shared Neighborhood Hits	157
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

FUT8_HUMAN
NC score	0.104504 (rank : 46)	θ value	1.38821 (rank : 106)
Query Neighborhood Hits	288	Target Neighborhood Hits	67	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BYC5, O00235, Q9BYC6, Q9P2U5, Q9P2U6	Gene names	FUT8
Domain Architecture
Description	Alpha-(1,6)-fucosyltransferase (EC 2.4.1.68) (Glycoprotein 6-alpha-L- fucosyltransferase) (GDP-fucose--glycoprotein fucosyltransferase) (GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase) (alpha1-6FucT) (Fucosyltransferase 8).

MUC7_HUMAN
NC score	0.103746 (rank : 47)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	288	Target Neighborhood Hits	538	Shared Neighborhood Hits	64
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

SRRM1_MOUSE
NC score	0.101435 (rank : 48)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	288	Target Neighborhood Hits	966	Shared Neighborhood Hits	101
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

WASL_MOUSE
NC score	0.100587 (rank : 49)	θ value	0.279714 (rank : 53)
Query Neighborhood Hits	288	Target Neighborhood Hits	339	Shared Neighborhood Hits	42
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

PRPE_HUMAN
NC score	0.099866 (rank : 50)	θ value	4.03905 (rank : 194)
Query Neighborhood Hits	288	Target Neighborhood Hits	44	Shared Neighborhood Hits	11
SwissProt Accessions	P02811	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide P-E (IB-9).

CO039_HUMAN
NC score	0.099396 (rank : 51)	θ value	0.0148317 (rank : 19)
Query Neighborhood Hits	288	Target Neighborhood Hits	264	Shared Neighborhood Hits	42
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

RGS3_HUMAN
NC score	0.099321 (rank : 52)	θ value	0.00665767 (rank : 15)
Query Neighborhood Hits	288	Target Neighborhood Hits	1375	Shared Neighborhood Hits	133
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

SF3B1_MOUSE
NC score	0.098242 (rank : 53)	θ value	0.0736092 (rank : 32)
Query Neighborhood Hits	288	Target Neighborhood Hits	352	Shared Neighborhood Hits	50
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_HUMAN
NC score	0.098198 (rank : 54)	θ value	0.0736092 (rank : 31)
Query Neighborhood Hits	288	Target Neighborhood Hits	341	Shared Neighborhood Hits	49
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

ARHG7_MOUSE
NC score	0.097111 (rank : 55)	θ value	4.03905 (rank : 179)
Query Neighborhood Hits	288	Target Neighborhood Hits	396	Shared Neighborhood Hits	61
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

FUT8_MOUSE
NC score	0.096765 (rank : 56)	θ value	2.36792 (rank : 142)
Query Neighborhood Hits	288	Target Neighborhood Hits	115	Shared Neighborhood Hits	30
SwissProt Accessions	Q9WTS2, Q921U1	Gene names	Fut8
Domain Architecture
Description	Alpha-(1,6)-fucosyltransferase (EC 2.4.1.68) (Glycoprotein 6-alpha-L- fucosyltransferase) (GDP-fucose--glycoprotein fucosyltransferase) (GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase) (alpha1-6FucT) (Fucosyltransferase 8).

WASL_HUMAN
NC score	0.096563 (rank : 57)	θ value	5.27518 (rank : 223)
Query Neighborhood Hits	288	Target Neighborhood Hits	312	Shared Neighborhood Hits	42
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

ANKS1_MOUSE
NC score	0.096389 (rank : 58)	θ value	0.00175202 (rank : 11)
Query Neighborhood Hits	288	Target Neighborhood Hits	453	Shared Neighborhood Hits	37
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

ARHG7_HUMAN
NC score	0.095440 (rank : 59)	θ value	3.0926 (rank : 156)
Query Neighborhood Hits	288	Target Neighborhood Hits	347	Shared Neighborhood Hits	59
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

STAC_HUMAN
NC score	0.094759 (rank : 60)	θ value	8.99809 (rank : 282)
Query Neighborhood Hits	288	Target Neighborhood Hits	276	Shared Neighborhood Hits	54
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

PRP2_MOUSE
NC score	0.094594 (rank : 61)	θ value	8.99809 (rank : 273)
Query Neighborhood Hits	288	Target Neighborhood Hits	347	Shared Neighborhood Hits	43
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

GSCR1_HUMAN
NC score	0.094284 (rank : 62)	θ value	1.06291 (rank : 94)
Query Neighborhood Hits	288	Target Neighborhood Hits	674	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

DOCK1_HUMAN
NC score	0.092889 (rank : 63)	θ value	0.0252991 (rank : 22)
Query Neighborhood Hits	288	Target Neighborhood Hits	191	Shared Neighborhood Hits	52
SwissProt Accessions	Q14185	Gene names	DOCK1
Domain Architecture
Description	Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180).

SPN90_HUMAN
NC score	0.092037 (rank : 64)	θ value	1.06291 (rank : 99)
Query Neighborhood Hits	288	Target Neighborhood Hits	157	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NZQ3, Q9UGM8	Gene names	NCKIPSD, AF3P21, SPIN90
Domain Architecture
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (AF3p21) (Diaphanous protein-interacting protein) (Dia-interacting protein 1) (DIP-1).

ABI2_HUMAN
NC score	0.090891 (rank : 65)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	288	Target Neighborhood Hits	350	Shared Neighborhood Hits	80
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

SRC8_MOUSE
NC score	0.089800 (rank : 66)	θ value	8.99809 (rank : 280)
Query Neighborhood Hits	288	Target Neighborhood Hits	292	Shared Neighborhood Hits	62
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

CIC_HUMAN
NC score	0.089604 (rank : 67)	θ value	1.06291 (rank : 92)
Query Neighborhood Hits	288	Target Neighborhood Hits	992	Shared Neighborhood Hits	103
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

SRRM1_HUMAN
NC score	0.089061 (rank : 68)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	288	Target Neighborhood Hits	690	Shared Neighborhood Hits	70
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SH3G3_MOUSE
NC score	0.089048 (rank : 69)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	288	Target Neighborhood Hits	236	Shared Neighborhood Hits	52
SwissProt Accessions	Q62421	Gene names	Sh3gl3, Sh3d2c, Sh3d2c2
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (SH3p13).

SRC8_HUMAN
NC score	0.088830 (rank : 70)	θ value	8.99809 (rank : 279)
Query Neighborhood Hits	288	Target Neighborhood Hits	269	Shared Neighborhood Hits	58
SwissProt Accessions	Q14247	Gene names	CTTN, EMS1
Domain Architecture
Description	Src substrate cortactin (Amplaxin) (Oncogene EMS1).

NFH_MOUSE
NC score	0.088822 (rank : 71)	θ value	8.11959e-09 (rank : 5)
Query Neighborhood Hits	288	Target Neighborhood Hits	2247	Shared Neighborhood Hits	154
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

ARHG6_HUMAN
NC score	0.088663 (rank : 72)	θ value	4.03905 (rank : 178)
Query Neighborhood Hits	288	Target Neighborhood Hits	376	Shared Neighborhood Hits	59
SwissProt Accessions	Q15052, Q15396, Q5JQ66, Q86XH0	Gene names	ARHGEF6, COOL2, KIAA0006, PIXA
Domain Architecture
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).

WASIP_HUMAN
NC score	0.088613 (rank : 73)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	288	Target Neighborhood Hits	458	Shared Neighborhood Hits	49
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

TAF4_HUMAN
NC score	0.088098 (rank : 74)	θ value	8.99809 (rank : 283)
Query Neighborhood Hits	288	Target Neighborhood Hits	687	Shared Neighborhood Hits	68
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

ANKS1_HUMAN
NC score	0.087771 (rank : 75)	θ value	0.00175202 (rank : 10)
Query Neighborhood Hits	288	Target Neighborhood Hits	438	Shared Neighborhood Hits	30
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

HCLS1_MOUSE
NC score	0.087677 (rank : 76)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	288	Target Neighborhood Hits	329	Shared Neighborhood Hits	71
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

SH3G2_HUMAN
NC score	0.087664 (rank : 77)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	288	Target Neighborhood Hits	324	Shared Neighborhood Hits	57
SwissProt Accessions	Q99962, Q9NQK5	Gene names	SH3GL2, CNSA2, SH3D2A
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (EEN-B1).

PRRT3_HUMAN
NC score	0.087456 (rank : 78)	θ value	0.813845 (rank : 86)
Query Neighborhood Hits	288	Target Neighborhood Hits	998	Shared Neighborhood Hits	116
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

PCLO_MOUSE
NC score	0.087287 (rank : 79)	θ value	0.0736092 (rank : 28)
Query Neighborhood Hits	288	Target Neighborhood Hits	2275	Shared Neighborhood Hits	163
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

EFS_HUMAN
NC score	0.087175 (rank : 80)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	288	Target Neighborhood Hits	348	Shared Neighborhood Hits	74
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

BASP_MOUSE
NC score	0.086631 (rank : 81)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	288	Target Neighborhood Hits	260	Shared Neighborhood Hits	40
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

PRP1_HUMAN
NC score	0.086466 (rank : 82)	θ value	1.38821 (rank : 111)
Query Neighborhood Hits	288	Target Neighborhood Hits	385	Shared Neighborhood Hits	54
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

ARHGF_HUMAN
NC score	0.086126 (rank : 83)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	288	Target Neighborhood Hits	214	Shared Neighborhood Hits	36
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

BASP_HUMAN
NC score	0.085433 (rank : 84)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	288	Target Neighborhood Hits	321	Shared Neighborhood Hits	44
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

HCLS1_HUMAN
NC score	0.085326 (rank : 85)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	288	Target Neighborhood Hits	358	Shared Neighborhood Hits	73
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

SH3G3_HUMAN
NC score	0.085209 (rank : 86)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	288	Target Neighborhood Hits	222	Shared Neighborhood Hits	51
SwissProt Accessions	Q99963, O43553, O43554	Gene names	SH3GL3, CNSA3, SH3D2C
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (EEN-B2).

SH3G1_HUMAN
NC score	0.085054 (rank : 87)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	288	Target Neighborhood Hits	307	Shared Neighborhood Hits	59
SwissProt Accessions	Q99961, Q99668	Gene names	SH3GL1, CNSA1, SH3D2B
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL).

ABI2_MOUSE
NC score	0.084487 (rank : 88)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	288	Target Neighborhood Hits	266	Shared Neighborhood Hits	63
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

PRB4S_HUMAN
NC score	0.084454 (rank : 89)	θ value	8.99809 (rank : 272)
Query Neighborhood Hits	288	Target Neighborhood Hits	330	Shared Neighborhood Hits	51
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

SH3G2_MOUSE
NC score	0.084400 (rank : 90)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	288	Target Neighborhood Hits	319	Shared Neighborhood Hits	57
SwissProt Accessions	Q62420	Gene names	Sh3gl2, Sh3d2a
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (SH3p4).

STS1_HUMAN
NC score	0.083820 (rank : 91)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	288	Target Neighborhood Hits	106	Shared Neighborhood Hits	41
SwissProt Accessions	Q8TF42, Q53GT5, Q53GT8, Q8NBV7, Q96IG9, Q96NZ2	Gene names	STS1, KIAA1959
Domain Architecture	No domain graphic available
Description	Suppressor of T-cell receptor signaling 1 (Sts-1) (Cbl-interacting protein p70).

COIA1_HUMAN
NC score	0.082974 (rank : 92)	θ value	0.0961366 (rank : 34)
Query Neighborhood Hits	288	Target Neighborhood Hits	447	Shared Neighborhood Hits	71
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

TMAP1_HUMAN
NC score	0.082149 (rank : 93)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	288	Target Neighborhood Hits	140	Shared Neighborhood Hits	31
SwissProt Accessions	P84157	Gene names	TMAP1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

ITSN1_MOUSE
NC score	0.082099 (rank : 94)	θ value	1.81305 (rank : 125)
Query Neighborhood Hits	288	Target Neighborhood Hits	1669	Shared Neighborhood Hits	107
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

SH3G1_MOUSE
NC score	0.082076 (rank : 95)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	288	Target Neighborhood Hits	291	Shared Neighborhood Hits	54
SwissProt Accessions	Q62419	Gene names	Sh3gl1, Sh3d2b
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (SH3p8).

ITSN1_HUMAN
NC score	0.081865 (rank : 96)	θ value	1.38821 (rank : 107)
Query Neighborhood Hits	288	Target Neighborhood Hits	1757	Shared Neighborhood Hits	106
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

SRRM2_MOUSE
NC score	0.081283 (rank : 97)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	288	Target Neighborhood Hits	1470	Shared Neighborhood Hits	102
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

ZN598_HUMAN
NC score	0.081275 (rank : 98)	θ value	0.163984 (rank : 45)
Query Neighborhood Hits	288	Target Neighborhood Hits	339	Shared Neighborhood Hits	34
SwissProt Accessions	Q86UK7, Q8IW49, Q8N3D9, Q96FG3, Q9H7J3	Gene names	ZNF598
Domain Architecture	No domain graphic available
Description	Zinc finger protein 598.

STS1_MOUSE
NC score	0.080994 (rank : 99)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	288	Target Neighborhood Hits	104	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BGG7, Q3U8Z2, Q8BMW9	Gene names	Sts1
Domain Architecture	No domain graphic available
Description	Suppressor of T-cell receptor signaling 1 (Sts-1) (Cbl-interacting protein p70).

ARH_HUMAN
NC score	0.080589 (rank : 100)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	288	Target Neighborhood Hits	38	Shared Neighborhood Hits	8
SwissProt Accessions	Q5SW96, Q6TQS9, Q8N2Y0, Q9UFI9	Gene names	LDLRAP1, ARH
Domain Architecture	No domain graphic available
Description	Low density lipoprotein receptor adapter protein 1 (Autosomal recessive hypercholesterolemia protein).

BIN1_HUMAN
NC score	0.080236 (rank : 101)	θ value	3.0926 (rank : 158)
Query Neighborhood Hits	288	Target Neighborhood Hits	335	Shared Neighborhood Hits	70
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

ABI1_MOUSE
NC score	0.080105 (rank : 102)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	288	Target Neighborhood Hits	246	Shared Neighborhood Hits	63
SwissProt Accessions	Q8CBW3, Q60747, Q91ZM5, Q923I9, Q99KH4	Gene names	Abi1, Ssh3bp1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Ablphilin-1).

EFS_MOUSE
NC score	0.080085 (rank : 103)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	288	Target Neighborhood Hits	389	Shared Neighborhood Hits	83
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

NEBU_HUMAN
NC score	0.079959 (rank : 104)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	288	Target Neighborhood Hits	420	Shared Neighborhood Hits	62
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

RP1L1_HUMAN
NC score	0.079541 (rank : 105)	θ value	2.36792 (rank : 149)
Query Neighborhood Hits	288	Target Neighborhood Hits	1072	Shared Neighborhood Hits	110
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

APBA1_HUMAN
NC score	0.079113 (rank : 106)	θ value	1.06291 (rank : 90)
Query Neighborhood Hits	288	Target Neighborhood Hits	325	Shared Neighborhood Hits	36
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

MUC1_HUMAN
NC score	0.079068 (rank : 107)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	288	Target Neighborhood Hits	975	Shared Neighborhood Hits	110
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

SNX9_HUMAN
NC score	0.078990 (rank : 108)	θ value	5.27518 (rank : 220)
Query Neighborhood Hits	288	Target Neighborhood Hits	148	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y5X1, Q9BSI7, Q9BVM1, Q9UJH6, Q9UP20	Gene names	SNX9, SH3PX1
Domain Architecture
Description	Sorting nexin-9 (SH3 and PX domain-containing protein 1) (SDP1 protein).

ARHG6_MOUSE
NC score	0.078845 (rank : 109)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	288	Target Neighborhood Hits	394	Shared Neighborhood Hits	55
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

SON_HUMAN
NC score	0.078810 (rank : 110)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	288	Target Neighborhood Hits	1568	Shared Neighborhood Hits	142
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

DDEF1_MOUSE
NC score	0.078700 (rank : 111)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	288	Target Neighborhood Hits	592	Shared Neighborhood Hits	83
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

CRK_MOUSE
NC score	0.078549 (rank : 112)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	288	Target Neighborhood Hits	314	Shared Neighborhood Hits	61
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

NCF4_MOUSE
NC score	0.078536 (rank : 113)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	288	Target Neighborhood Hits	177	Shared Neighborhood Hits	47
SwissProt Accessions	P97369	Gene names	Ncf4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

ABI3_HUMAN
NC score	0.078513 (rank : 114)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	288	Target Neighborhood Hits	227	Shared Neighborhood Hits	61
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

TP53B_MOUSE
NC score	0.078422 (rank : 115)	θ value	0.0431538 (rank : 26)
Query Neighborhood Hits	288	Target Neighborhood Hits	644	Shared Neighborhood Hits	56
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

OGFR_MOUSE
NC score	0.078340 (rank : 116)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	288	Target Neighborhood Hits	584	Shared Neighborhood Hits	73
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

NUMBL_HUMAN
NC score	0.078180 (rank : 117)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	288	Target Neighborhood Hits	394	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

MARCS_HUMAN
NC score	0.077544 (rank : 118)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	288	Target Neighborhood Hits	204	Shared Neighborhood Hits	30
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

CO039_MOUSE
NC score	0.077313 (rank : 119)	θ value	4.03905 (rank : 181)
Query Neighborhood Hits	288	Target Neighborhood Hits	445	Shared Neighborhood Hits	53
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

SYN1_HUMAN
NC score	0.077053 (rank : 120)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	288	Target Neighborhood Hits	419	Shared Neighborhood Hits	53
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

GRAP_MOUSE
NC score	0.076158 (rank : 121)	θ value	1.81305 (rank : 122)
Query Neighborhood Hits	288	Target Neighborhood Hits	309	Shared Neighborhood Hits	66
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

NCF4_HUMAN
NC score	0.076147 (rank : 122)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	288	Target Neighborhood Hits	161	Shared Neighborhood Hits	42
SwissProt Accessions	Q15080, O60808, Q86U56, Q9BU98, Q9NP45	Gene names	NCF4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

SGIP1_HUMAN
NC score	0.076133 (rank : 123)	θ value	0.279714 (rank : 52)
Query Neighborhood Hits	288	Target Neighborhood Hits	198	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

TB182_HUMAN
NC score	0.075971 (rank : 124)	θ value	8.99809 (rank : 284)
Query Neighborhood Hits	288	Target Neighborhood Hits	414	Shared Neighborhood Hits	60
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

CAPON_HUMAN
NC score	0.075888 (rank : 125)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	288	Target Neighborhood Hits	35	Shared Neighborhood Hits	7
SwissProt Accessions	O75052, O43564	Gene names	NOS1AP, CAPON, KIAA0464
Domain Architecture	No domain graphic available
Description	Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (C--terminal PDZ ligand of neuronal nitric oxide synthase protein) (Nitric oxide synthase 1 adaptor protein).

CRK_HUMAN
NC score	0.075863 (rank : 126)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	288	Target Neighborhood Hits	308	Shared Neighborhood Hits	59
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

BIN1_MOUSE
NC score	0.075745 (rank : 127)	θ value	2.36792 (rank : 131)
Query Neighborhood Hits	288	Target Neighborhood Hits	283	Shared Neighborhood Hits	69
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

PCLO_HUMAN
NC score	0.075557 (rank : 128)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	288	Target Neighborhood Hits	2046	Shared Neighborhood Hits	137
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

DP13A_MOUSE
NC score	0.075416 (rank : 129)	θ value	1.81305 (rank : 121)
Query Neighborhood Hits	288	Target Neighborhood Hits	96	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K3H0, Q3UJP7, Q69ZJ9, Q8BWZ8, Q8VCJ8, Q9CUW4	Gene names	Appl1, Dip13a, Kiaa1428
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 alpha (Dip13 alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1).

DP13A_HUMAN
NC score	0.075231 (rank : 130)	θ value	1.81305 (rank : 120)
Query Neighborhood Hits	288	Target Neighborhood Hits	107	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UKG1, Q9P2B9	Gene names	APPL1, APPL, DIP13A, KIAA1428
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 alpha (Dip13 alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1).

CIC_MOUSE
NC score	0.075102 (rank : 131)	θ value	1.81305 (rank : 119)
Query Neighborhood Hits	288	Target Neighborhood Hits	742	Shared Neighborhood Hits	84
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CO3A1_MOUSE
NC score	0.075096 (rank : 132)	θ value	0.62314 (rank : 72)
Query Neighborhood Hits	288	Target Neighborhood Hits	466	Shared Neighborhood Hits	70
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

ABI1_HUMAN
NC score	0.074679 (rank : 133)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	288	Target Neighborhood Hits	257	Shared Neighborhood Hits	62
SwissProt Accessions	Q8IZP0, O15147, O76049, O95060, Q5W070, Q5W072, Q8TB63, Q96S81, Q9NXZ9, Q9NYB8	Gene names	ABI1, SSH3BP1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Nap1-binding protein) (Nap1BP) (Abl-binding protein 4) (AblBP4).

COIA1_MOUSE
NC score	0.074083 (rank : 134)	θ value	0.813845 (rank : 82)
Query Neighborhood Hits	288	Target Neighborhood Hits	481	Shared Neighborhood Hits	67
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

ARHGG_HUMAN
NC score	0.073795 (rank : 135)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	288	Target Neighborhood Hits	129	Shared Neighborhood Hits	30
SwissProt Accessions	Q5VV41, Q86TF0, Q99434	Gene names	ARHGEF16, NBR
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

ITSN2_HUMAN
NC score	0.073620 (rank : 136)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	288	Target Neighborhood Hits	1173	Shared Neighborhood Hits	79
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

VAV_MOUSE
NC score	0.073521 (rank : 137)	θ value	3.0926 (rank : 175)
Query Neighborhood Hits	288	Target Neighborhood Hits	430	Shared Neighborhood Hits	63
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

PRP5_HUMAN
NC score	0.073422 (rank : 138)	θ value	8.99809 (rank : 274)
Query Neighborhood Hits	288	Target Neighborhood Hits	108	Shared Neighborhood Hits	27
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

SNPC4_HUMAN
NC score	0.073317 (rank : 139)	θ value	0.813845 (rank : 89)
Query Neighborhood Hits	288	Target Neighborhood Hits	589	Shared Neighborhood Hits	92
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

CO1A1_HUMAN
NC score	0.073018 (rank : 140)	θ value	1.38821 (rank : 103)
Query Neighborhood Hits	288	Target Neighborhood Hits	475	Shared Neighborhood Hits	74
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

WASIP_MOUSE
NC score	0.072990 (rank : 141)	θ value	3.0926 (rank : 176)
Query Neighborhood Hits	288	Target Neighborhood Hits	392	Shared Neighborhood Hits	50
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

CO3A1_HUMAN
NC score	0.072635 (rank : 142)	θ value	1.38821 (rank : 104)
Query Neighborhood Hits	288	Target Neighborhood Hits	452	Shared Neighborhood Hits	72
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

MARCS_MOUSE
NC score	0.072605 (rank : 143)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	288	Target Neighborhood Hits	227	Shared Neighborhood Hits	33
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

CAPON_MOUSE
NC score	0.072277 (rank : 144)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	288	Target Neighborhood Hits	34	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D3A8, Q80TZ6	Gene names	Nos1ap, Capon, Kiaa0464
Domain Architecture	No domain graphic available
Description	Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (C--terminal PDZ ligand of neuronal nitric oxide synthase protein) (Nitric oxide synthase 1 adaptor protein).

CO5A2_HUMAN
NC score	0.072029 (rank : 145)	θ value	0.47712 (rank : 66)
Query Neighborhood Hits	288	Target Neighborhood Hits	760	Shared Neighborhood Hits	89
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

CO1A1_MOUSE
NC score	0.071579 (rank : 146)	θ value	2.36792 (rank : 137)
Query Neighborhood Hits	288	Target Neighborhood Hits	457	Shared Neighborhood Hits	79
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

P85A_MOUSE
NC score	0.071082 (rank : 147)	θ value	0.813845 (rank : 85)
Query Neighborhood Hits	288	Target Neighborhood Hits	435	Shared Neighborhood Hits	46
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

CN155_HUMAN
NC score	0.070671 (rank : 148)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	288	Target Neighborhood Hits	385	Shared Neighborhood Hits	45
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

MILK1_MOUSE
NC score	0.070448 (rank : 149)	θ value	0.0961366 (rank : 35)
Query Neighborhood Hits	288	Target Neighborhood Hits	788	Shared Neighborhood Hits	88
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

BAT2_HUMAN
NC score	0.070422 (rank : 150)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	288	Target Neighborhood Hits	931	Shared Neighborhood Hits	119
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

NCF1_HUMAN
NC score	0.070245 (rank : 151)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	288	Target Neighborhood Hits	198	Shared Neighborhood Hits	46
SwissProt Accessions	P14598, O43842, Q2PP07, Q9BU90, Q9BXI7, Q9BXI8, Q9UDV9, Q9UMU2	Gene names	NCF1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDa autosomal chronic granulomatous disease protein) (NOXO2).

NCK2_HUMAN
NC score	0.070119 (rank : 152)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	288	Target Neighborhood Hits	310	Shared Neighborhood Hits	62
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

ITSN2_MOUSE
NC score	0.069798 (rank : 153)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	288	Target Neighborhood Hits	1371	Shared Neighborhood Hits	80
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

NCK1_HUMAN
NC score	0.069762 (rank : 154)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	288	Target Neighborhood Hits	312	Shared Neighborhood Hits	59
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

NACAM_MOUSE
NC score	0.069723 (rank : 155)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	288	Target Neighborhood Hits	1866	Shared Neighborhood Hits	136
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

WASP_HUMAN
NC score	0.069227 (rank : 156)	θ value	1.38821 (rank : 112)
Query Neighborhood Hits	288	Target Neighborhood Hits	195	Shared Neighborhood Hits	37
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

PDXL2_MOUSE
NC score	0.068804 (rank : 157)	θ value	0.365318 (rank : 59)
Query Neighborhood Hits	288	Target Neighborhood Hits	213	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CAE9, Q8CFW3	Gene names	Podxl2
Domain Architecture	No domain graphic available
Description	Podocalyxin-like protein 2 precursor (Endoglycan).

NUMBL_MOUSE
NC score	0.068726 (rank : 158)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	288	Target Neighborhood Hits	147	Shared Neighborhood Hits	20
SwissProt Accessions	O08919, Q6NVG8	Gene names	Numbl, Nbl
Domain Architecture
Description	Numb-like protein.

ABI3_MOUSE
NC score	0.068721 (rank : 159)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	288	Target Neighborhood Hits	227	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

WIRE_HUMAN
NC score	0.068650 (rank : 160)	θ value	8.99809 (rank : 288)
Query Neighborhood Hits	288	Target Neighborhood Hits	329	Shared Neighborhood Hits	45
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

NCF1_MOUSE
NC score	0.068543 (rank : 161)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	288	Target Neighborhood Hits	198	Shared Neighborhood Hits	43
SwissProt Accessions	Q09014, O70144, Q9JI34	Gene names	Ncf1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K).

DBNL_HUMAN
NC score	0.068278 (rank : 162)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	288	Target Neighborhood Hits	244	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UJU6, P84070, Q6IAI8, Q96F30, Q96K74, Q9HBN8, Q9NR72	Gene names	DBNL, CMAP, SH3P7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein).

MAGE1_HUMAN
NC score	0.067723 (rank : 163)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	288	Target Neighborhood Hits	1389	Shared Neighborhood Hits	139
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

BAT2_MOUSE
NC score	0.066788 (rank : 164)	θ value	6.88961 (rank : 227)
Query Neighborhood Hits	288	Target Neighborhood Hits	947	Shared Neighborhood Hits	116
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CO2A1_HUMAN
NC score	0.066680 (rank : 165)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	288	Target Neighborhood Hits	486	Shared Neighborhood Hits	79
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

DIDO1_HUMAN
NC score	0.066531 (rank : 166)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	288	Target Neighborhood Hits	960	Shared Neighborhood Hits	115
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

DBNL_MOUSE
NC score	0.066500 (rank : 167)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	288	Target Neighborhood Hits	306	Shared Neighborhood Hits	52
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

MBD6_HUMAN
NC score	0.065992 (rank : 168)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	288	Target Neighborhood Hits	349	Shared Neighborhood Hits	45
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

VAV_HUMAN
NC score	0.065908 (rank : 169)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	288	Target Neighborhood Hits	452	Shared Neighborhood Hits	62
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

STAM1_MOUSE
NC score	0.065766 (rank : 170)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	288	Target Neighborhood Hits	273	Shared Neighborhood Hits	54
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

BCAR1_HUMAN
NC score	0.065728 (rank : 171)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	288	Target Neighborhood Hits	554	Shared Neighborhood Hits	94
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

RIMB1_HUMAN
NC score	0.065688 (rank : 172)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	288	Target Neighborhood Hits	1479	Shared Neighborhood Hits	124
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

PRR12_HUMAN
NC score	0.065353 (rank : 173)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	288	Target Neighborhood Hits	460	Shared Neighborhood Hits	52
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

SAPS1_HUMAN
NC score	0.065194 (rank : 174)	θ value	0.813845 (rank : 87)
Query Neighborhood Hits	288	Target Neighborhood Hits	704	Shared Neighborhood Hits	96
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

STAM1_HUMAN
NC score	0.065172 (rank : 175)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	288	Target Neighborhood Hits	271	Shared Neighborhood Hits	54
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

RAPH1_HUMAN
NC score	0.065137 (rank : 176)	θ value	6.88961 (rank : 241)
Query Neighborhood Hits	288	Target Neighborhood Hits	593	Shared Neighborhood Hits	64
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

GRB2_HUMAN
NC score	0.064694 (rank : 177)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	288	Target Neighborhood Hits	310	Shared Neighborhood Hits	58
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

CRKL_HUMAN
NC score	0.064522 (rank : 178)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	288	Target Neighborhood Hits	313	Shared Neighborhood Hits	57
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

CO5A1_HUMAN
NC score	0.064402 (rank : 179)	θ value	5.27518 (rank : 200)
Query Neighborhood Hits	288	Target Neighborhood Hits	434	Shared Neighborhood Hits	74
SwissProt Accessions	P20908, Q15094, Q5SUX4	Gene names	COL5A1
Domain Architecture
Description	Collagen alpha-1(V) chain precursor.

VAV2_MOUSE
NC score	0.064373 (rank : 180)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	288	Target Neighborhood Hits	456	Shared Neighborhood Hits	66
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

GRB2_MOUSE
NC score	0.064238 (rank : 181)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	288	Target Neighborhood Hits	312	Shared Neighborhood Hits	58
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

CRKL_MOUSE
NC score	0.064061 (rank : 182)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	288	Target Neighborhood Hits	307	Shared Neighborhood Hits	57
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

MLL2_HUMAN
NC score	0.063913 (rank : 183)	θ value	0.62314 (rank : 76)
Query Neighborhood Hits	288	Target Neighborhood Hits	1788	Shared Neighborhood Hits	126
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

STAM2_MOUSE
NC score	0.063767 (rank : 184)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	288	Target Neighborhood Hits	285	Shared Neighborhood Hits	52
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

SHAN1_HUMAN
NC score	0.063742 (rank : 185)	θ value	1.06291 (rank : 98)
Query Neighborhood Hits	288	Target Neighborhood Hits	1041	Shared Neighborhood Hits	106
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

APBA2_MOUSE
NC score	0.063679 (rank : 186)	θ value	1.81305 (rank : 116)
Query Neighborhood Hits	288	Target Neighborhood Hits	219	Shared Neighborhood Hits	22
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

GGN_HUMAN
NC score	0.063602 (rank : 187)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	288	Target Neighborhood Hits	269	Shared Neighborhood Hits	33
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

CO4A5_HUMAN
NC score	0.063498 (rank : 188)	θ value	0.47712 (rank : 64)
Query Neighborhood Hits	288	Target Neighborhood Hits	383	Shared Neighborhood Hits	61
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

VAV2_HUMAN
NC score	0.063441 (rank : 189)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	288	Target Neighborhood Hits	453	Shared Neighborhood Hits	60
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

IASPP_MOUSE
NC score	0.063405 (rank : 190)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	288	Target Neighborhood Hits	1024	Shared Neighborhood Hits	141
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

WASP_MOUSE
NC score	0.062970 (rank : 191)	θ value	3.0926 (rank : 177)
Query Neighborhood Hits	288	Target Neighborhood Hits	223	Shared Neighborhood Hits	33
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

CO9A3_HUMAN
NC score	0.062815 (rank : 192)	θ value	2.36792 (rank : 138)
Query Neighborhood Hits	288	Target Neighborhood Hits	361	Shared Neighborhood Hits	64
SwissProt Accessions	Q14050, Q13681, Q9H4G9, Q9UPE2	Gene names	COL9A3
Domain Architecture	No domain graphic available
Description	Collagen alpha-3(IX) chain precursor.

CO5A1_MOUSE
NC score	0.062811 (rank : 193)	θ value	5.27518 (rank : 201)
Query Neighborhood Hits	288	Target Neighborhood Hits	419	Shared Neighborhood Hits	70
SwissProt Accessions	O88207	Gene names	Col5a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(V) chain precursor.

SON_MOUSE
NC score	0.062808 (rank : 194)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	288	Target Neighborhood Hits	957	Shared Neighborhood Hits	94
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

BAZ2A_MOUSE
NC score	0.062737 (rank : 195)	θ value	6.88961 (rank : 228)
Query Neighborhood Hits	288	Target Neighborhood Hits	744	Shared Neighborhood Hits	75
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

CO4A6_HUMAN
NC score	0.062695 (rank : 196)	θ value	0.47712 (rank : 65)
Query Neighborhood Hits	288	Target Neighborhood Hits	318	Shared Neighborhood Hits	51
SwissProt Accessions	Q14031, Q12823, Q14053, Q5JYH6, Q9NQM5, Q9NTX3, Q9UJ76, Q9UMG6, Q9Y4L4	Gene names	COL4A6
Domain Architecture
Description	Collagen alpha-6(IV) chain precursor.

CO2A1_MOUSE
NC score	0.062677 (rank : 197)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	288	Target Neighborhood Hits	483	Shared Neighborhood Hits	71
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

COFA1_MOUSE
NC score	0.062675 (rank : 198)	θ value	5.27518 (rank : 203)
Query Neighborhood Hits	288	Target Neighborhood Hits	305	Shared Neighborhood Hits	56
SwissProt Accessions	O35206, Q9EQD9	Gene names	Col15a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV)].

CN104_HUMAN
NC score	0.062664 (rank : 199)	θ value	0.47712 (rank : 63)
Query Neighborhood Hits	288	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NVR5, Q86TY8, Q969Z5	Gene names	C14orf104
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf104.

STAM2_HUMAN
NC score	0.062498 (rank : 200)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	288	Target Neighborhood Hits	288	Shared Neighborhood Hits	56
SwissProt Accessions	O75886, Q7LDQ0, Q9UF58	Gene names	STAM2
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2).

GRAP_HUMAN
NC score	0.061962 (rank : 201)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	288	Target Neighborhood Hits	307	Shared Neighborhood Hits	62
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

APBA2_HUMAN
NC score	0.061714 (rank : 202)	θ value	1.81305 (rank : 115)
Query Neighborhood Hits	288	Target Neighborhood Hits	220	Shared Neighborhood Hits	16
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

COBA1_HUMAN
NC score	0.061441 (rank : 203)	θ value	8.99809 (rank : 257)
Query Neighborhood Hits	288	Target Neighborhood Hits	491	Shared Neighborhood Hits	71
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

P85A_HUMAN
NC score	0.061404 (rank : 204)	θ value	2.36792 (rank : 147)
Query Neighborhood Hits	288	Target Neighborhood Hits	479	Shared Neighborhood Hits	43
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

DP13B_HUMAN
NC score	0.061328 (rank : 205)	θ value	4.03905 (rank : 184)
Query Neighborhood Hits	288	Target Neighborhood Hits	58	Shared Neighborhood Hits	12
SwissProt Accessions	Q8NEU8, Q8N4R7, Q9NVL2	Gene names	DIP13B, APPL2
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 beta (Dip13 beta) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 2).

BCL9_HUMAN
NC score	0.061256 (rank : 206)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	288	Target Neighborhood Hits	1008	Shared Neighborhood Hits	106
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

CO1A2_MOUSE
NC score	0.061246 (rank : 207)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	288	Target Neighborhood Hits	388	Shared Neighborhood Hits	59
SwissProt Accessions	Q01149, Q8CGA5	Gene names	Col1a2, Cola2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

GRAP2_MOUSE
NC score	0.060991 (rank : 208)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	288	Target Neighborhood Hits	297	Shared Neighborhood Hits	58
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

CK037_HUMAN
NC score	0.060944 (rank : 209)	θ value	1.06291 (rank : 93)
Query Neighborhood Hits	288	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	Q96N53	Gene names	C11orf37
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C11orf37.

BCL9_MOUSE
NC score	0.060918 (rank : 210)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	288	Target Neighborhood Hits	770	Shared Neighborhood Hits	101
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

SPAG8_HUMAN
NC score	0.060697 (rank : 211)	θ value	1.81305 (rank : 130)
Query Neighborhood Hits	288	Target Neighborhood Hits	56	Shared Neighborhood Hits	11
SwissProt Accessions	Q99932, Q12937, Q5TCV8, Q8WWB4	Gene names	SPAG8
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 8 (Sperm membrane protein 1) (SMP-1) (HSD-1) (Sperm membrane protein BS-84).

COGA1_HUMAN
NC score	0.060643 (rank : 212)	θ value	4.03905 (rank : 182)
Query Neighborhood Hits	288	Target Neighborhood Hits	345	Shared Neighborhood Hits	61
SwissProt Accessions	Q07092	Gene names	COL16A1
Domain Architecture
Description	Collagen alpha-1(XVI) chain precursor.

CO4A1_MOUSE
NC score	0.060443 (rank : 213)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	288	Target Neighborhood Hits	450	Shared Neighborhood Hits	73
SwissProt Accessions	P02463	Gene names	Col4a1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

CO5A3_HUMAN
NC score	0.060272 (rank : 214)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	288	Target Neighborhood Hits	433	Shared Neighborhood Hits	74
SwissProt Accessions	P25940, Q9NZQ6	Gene names	COL5A3
Domain Architecture
Description	Collagen alpha-3(V) chain precursor.

AMPH_HUMAN
NC score	0.060184 (rank : 215)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	288	Target Neighborhood Hits	455	Shared Neighborhood Hits	61
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

GRIN1_MOUSE
NC score	0.060146 (rank : 216)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	288	Target Neighborhood Hits	337	Shared Neighborhood Hits	36
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

BCAR1_MOUSE
NC score	0.059708 (rank : 217)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	288	Target Neighborhood Hits	438	Shared Neighborhood Hits	87
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

SNX9_MOUSE
NC score	0.059642 (rank : 218)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	288	Target Neighborhood Hits	141	Shared Neighborhood Hits	35
SwissProt Accessions	Q91VH2	Gene names	Snx9
Domain Architecture
Description	Sorting nexin-9.

PELP1_MOUSE
NC score	0.059465 (rank : 219)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	288	Target Neighborhood Hits	709	Shared Neighborhood Hits	94
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

ENAH_MOUSE
NC score	0.059435 (rank : 220)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	288	Target Neighborhood Hits	919	Shared Neighborhood Hits	69
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

COHA1_MOUSE
NC score	0.059302 (rank : 221)	θ value	6.88961 (rank : 231)
Query Neighborhood Hits	288	Target Neighborhood Hits	414	Shared Neighborhood Hits	62
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

CO4A1_HUMAN
NC score	0.059168 (rank : 222)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	288	Target Neighborhood Hits	425	Shared Neighborhood Hits	64
SwissProt Accessions	P02462	Gene names	COL4A1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

SNPC2_MOUSE
NC score	0.059132 (rank : 223)	θ value	0.365318 (rank : 60)
Query Neighborhood Hits	288	Target Neighborhood Hits	83	Shared Neighborhood Hits	15
SwissProt Accessions	Q91XA5, Q3UK17, Q8CBS9	Gene names	Snapc2
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 2 (SNAPc subunit 2) (snRNA- activating protein complex 45 kDa subunit) (SNAPc 45 kDa subunit) (Small nuclear RNA-activating complex polypeptide 2).

SHC1_MOUSE
NC score	0.059063 (rank : 224)	θ value	2.36792 (rank : 152)
Query Neighborhood Hits	288	Target Neighborhood Hits	180	Shared Neighborhood Hits	24
SwissProt Accessions	P98083, Q3U2Q7, Q8BFY3, Q8K4C6, Q8K4C7	Gene names	Shc1, Shc, ShcA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

SRRM2_HUMAN
NC score	0.059063 (rank : 225)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	288	Target Neighborhood Hits	1296	Shared Neighborhood Hits	89
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

K2027_HUMAN
NC score	0.059012 (rank : 226)	θ value	1.06291 (rank : 96)
Query Neighborhood Hits	288	Target Neighborhood Hits	194	Shared Neighborhood Hits	25
SwissProt Accessions	Q6ZVF9, Q8IVE4	Gene names	KIAA2027
Domain Architecture	No domain graphic available
Description	Protein KIAA2027.

AMPH_MOUSE
NC score	0.058775 (rank : 227)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	288	Target Neighborhood Hits	291	Shared Neighborhood Hits	52
SwissProt Accessions	Q7TQF7, Q8R1C4	Gene names	Amph, Amph1
Domain Architecture
Description	Amphiphysin.

ZN385_HUMAN
NC score	0.058729 (rank : 228)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	288	Target Neighborhood Hits	614	Shared Neighborhood Hits	93
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

WIRE_MOUSE
NC score	0.058633 (rank : 229)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	288	Target Neighborhood Hits	310	Shared Neighborhood Hits	44
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

TCGAP_HUMAN
NC score	0.058592 (rank : 230)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	288	Target Neighborhood Hits	872	Shared Neighborhood Hits	137
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

COBA1_MOUSE
NC score	0.058578 (rank : 231)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	288	Target Neighborhood Hits	487	Shared Neighborhood Hits	73
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

PAF49_MOUSE
NC score	0.058532 (rank : 232)	θ value	5.27518 (rank : 216)
Query Neighborhood Hits	288	Target Neighborhood Hits	48	Shared Neighborhood Hits	5
SwissProt Accessions	Q76KJ5, Q8K0Y9	Gene names	Cd3eap, Ase1, Paf49
Domain Architecture	No domain graphic available
Description	RNA polymerase I-associated factor PAF49 (Anti-sense to ERCC-1 protein) (ASE-1) (CD3-epsilon-associated protein) (CD3E-associated protein).

COBA2_HUMAN
NC score	0.058348 (rank : 233)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	288	Target Neighborhood Hits	408	Shared Neighborhood Hits	62
SwissProt Accessions	P13942, Q07751, Q13271, Q13272, Q13273, Q99866, Q9UIP9	Gene names	COL11A2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

CO1A2_HUMAN
NC score	0.058345 (rank : 234)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	288	Target Neighborhood Hits	329	Shared Neighborhood Hits	53
SwissProt Accessions	P08123, P02464, Q9UEB6, Q9UPH0	Gene names	COL1A2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

SHC1_HUMAN
NC score	0.058068 (rank : 235)	θ value	2.36792 (rank : 151)
Query Neighborhood Hits	288	Target Neighborhood Hits	170	Shared Neighborhood Hits	22
SwissProt Accessions	P29353, O15290, Q8N4K5, Q96CL1	Gene names	SHC1, SHC, SHCA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

CO4A4_HUMAN
NC score	0.058048 (rank : 236)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	288	Target Neighborhood Hits	440	Shared Neighborhood Hits	68
SwissProt Accessions	P53420	Gene names	COL4A4
Domain Architecture
Description	Collagen alpha-4(IV) chain precursor.

SFPQ_HUMAN
NC score	0.057993 (rank : 237)	θ value	1.81305 (rank : 129)
Query Neighborhood Hits	288	Target Neighborhood Hits	986	Shared Neighborhood Hits	67
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

CO7A1_HUMAN
NC score	0.057815 (rank : 238)	θ value	5.27518 (rank : 202)
Query Neighborhood Hits	288	Target Neighborhood Hits	807	Shared Neighborhood Hits	84
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

CO4A2_MOUSE
NC score	0.057754 (rank : 239)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	288	Target Neighborhood Hits	492	Shared Neighborhood Hits	72
SwissProt Accessions	P08122, Q61375	Gene names	Col4a2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

BRCA1_MOUSE
NC score	0.057656 (rank : 240)	θ value	0.0252991 (rank : 21)
Query Neighborhood Hits	288	Target Neighborhood Hits	436	Shared Neighborhood Hits	12
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

COBA2_MOUSE
NC score	0.057447 (rank : 241)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	288	Target Neighborhood Hits	501	Shared Neighborhood Hits	78
SwissProt Accessions	Q64739, Q61432, Q9Z1W0	Gene names	Col11a2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

GRAP2_HUMAN
NC score	0.057349 (rank : 242)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	288	Target Neighborhood Hits	304	Shared Neighborhood Hits	56
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

RUSC1_HUMAN
NC score	0.057272 (rank : 243)	θ value	8.99809 (rank : 276)
Query Neighborhood Hits	288	Target Neighborhood Hits	226	Shared Neighborhood Hits	49
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

DP13B_MOUSE
NC score	0.057056 (rank : 244)	θ value	8.99809 (rank : 260)
Query Neighborhood Hits	288	Target Neighborhood Hits	58	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K3G9, Q99LT7	Gene names	Dip13b, Appl2, Dip3b
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 beta (Dip13 beta) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 2).

SYN1_MOUSE
NC score	0.056940 (rank : 245)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	288	Target Neighborhood Hits	363	Shared Neighborhood Hits	41
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

IWS1_HUMAN
NC score	0.056700 (rank : 246)	θ value	1.81305 (rank : 126)
Query Neighborhood Hits	288	Target Neighborhood Hits	1241	Shared Neighborhood Hits	73
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

CCNK_MOUSE
NC score	0.056512 (rank : 247)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	288	Target Neighborhood Hits	350	Shared Neighborhood Hits	33
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

SC24C_HUMAN
NC score	0.056322 (rank : 248)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	288	Target Neighborhood Hits	662	Shared Neighborhood Hits	87
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

CO4A2_HUMAN
NC score	0.056296 (rank : 249)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	288	Target Neighborhood Hits	454	Shared Neighborhood Hits	68
SwissProt Accessions	P08572	Gene names	COL4A2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

ATN1_HUMAN
NC score	0.055911 (rank : 250)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	288	Target Neighborhood Hits	676	Shared Neighborhood Hits	60
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

SET1A_HUMAN
NC score	0.055590 (rank : 251)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	288	Target Neighborhood Hits	690	Shared Neighborhood Hits	61
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

ARI1A_HUMAN
NC score	0.055452 (rank : 252)	θ value	6.88961 (rank : 226)
Query Neighborhood Hits	288	Target Neighborhood Hits	787	Shared Neighborhood Hits	87
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

TCOF_MOUSE
NC score	0.055408 (rank : 253)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	288	Target Neighborhood Hits	471	Shared Neighborhood Hits	52
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

CONA1_HUMAN
NC score	0.055383 (rank : 254)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	288	Target Neighborhood Hits	281	Shared Neighborhood Hits	53
SwissProt Accessions	Q86Y22, Q8IVR4, Q9NT93	Gene names	COL23A1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

RIMB2_HUMAN
NC score	0.055342 (rank : 255)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	288	Target Neighborhood Hits	263	Shared Neighborhood Hits	52
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

PSL1_HUMAN
NC score	0.055325 (rank : 256)	θ value	3.0926 (rank : 171)
Query Neighborhood Hits	288	Target Neighborhood Hits	650	Shared Neighborhood Hits	93
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

TGON2_HUMAN
NC score	0.055204 (rank : 257)	θ value	8.99809 (rank : 286)
Query Neighborhood Hits	288	Target Neighborhood Hits	1037	Shared Neighborhood Hits	78
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

CO9A2_MOUSE
NC score	0.054981 (rank : 258)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	288	Target Neighborhood Hits	279	Shared Neighborhood Hits	45
SwissProt Accessions	Q07643	Gene names	Col9a2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(IX) chain precursor.

PELP1_HUMAN
NC score	0.054961 (rank : 259)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	288	Target Neighborhood Hits	596	Shared Neighborhood Hits	62
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

CO4A3_HUMAN
NC score	0.054939 (rank : 260)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	288	Target Neighborhood Hits	421	Shared Neighborhood Hits	56
SwissProt Accessions	Q01955, Q9BQT2	Gene names	COL4A3
Domain Architecture
Description	Collagen alpha-3(IV) chain precursor (Goodpasture antigen).

STAC3_MOUSE
NC score	0.054919 (rank : 261)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	288	Target Neighborhood Hits	232	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC3_HUMAN
NC score	0.054834 (rank : 262)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	288	Target Neighborhood Hits	228	Shared Neighborhood Hits	43
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

CO9A1_MOUSE
NC score	0.054819 (rank : 263)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	288	Target Neighborhood Hits	477	Shared Neighborhood Hits	76
SwissProt Accessions	Q05722, Q61269, Q61270, Q61433, Q61940	Gene names	Col9a1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

FMN1B_MOUSE
NC score	0.054774 (rank : 264)	θ value	2.36792 (rank : 141)
Query Neighborhood Hits	288	Target Neighborhood Hits	447	Shared Neighborhood Hits	42
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

VCX3_HUMAN
NC score	0.054557 (rank : 265)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	288	Target Neighborhood Hits	105	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NNX9, Q9P0H4	Gene names	VCX3A, VCX3, VCX8R, VCXA
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 3 (VCX-A protein) (Variably charged protein X-A) (Variable charge protein on X with eight repeats) (VCX- 8r).

YLPM1_HUMAN
NC score	0.054508 (rank : 266)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	288	Target Neighborhood Hits	670	Shared Neighborhood Hits	71
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

LEO1_MOUSE
NC score	0.054399 (rank : 267)	θ value	0.0563607 (rank : 27)
Query Neighborhood Hits	288	Target Neighborhood Hits	946	Shared Neighborhood Hits	32
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

NUMB_HUMAN
NC score	0.054294 (rank : 268)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	288	Target Neighborhood Hits	112	Shared Neighborhood Hits	13
SwissProt Accessions	P49757, Q6NUQ7, Q86SY1, Q8WW73, Q9UBG1, Q9UEQ4, Q9UKE8, Q9UKE9, Q9UKF0, Q9UQJ4	Gene names	NUMB
Domain Architecture
Description	Protein numb homolog (h-Numb) (Protein S171).

ASPP1_MOUSE
NC score	0.054257 (rank : 269)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	288	Target Neighborhood Hits	1244	Shared Neighborhood Hits	121
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

COFA1_HUMAN
NC score	0.054251 (rank : 270)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	288	Target Neighborhood Hits	292	Shared Neighborhood Hits	55
SwissProt Accessions	P39059, Q5T6J4, Q9Y4W4	Gene names	COL15A1
Domain Architecture
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV) (Restin) (Related to endostatin)].

CO9A1_HUMAN
NC score	0.054067 (rank : 271)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	288	Target Neighborhood Hits	420	Shared Neighborhood Hits	66
SwissProt Accessions	P20849, Q13699, Q13700, Q5TF52, Q6P467, Q96BM8, Q99225, Q9H151, Q9H152, Q9Y6P2, Q9Y6P3	Gene names	COL9A1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

TAU_HUMAN
NC score	0.053968 (rank : 272)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	288	Target Neighborhood Hits	448	Shared Neighborhood Hits	66
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

CO9A2_HUMAN
NC score	0.053916 (rank : 273)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	288	Target Neighborhood Hits	261	Shared Neighborhood Hits	48
SwissProt Accessions	Q14055	Gene names	COL9A2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(IX) chain precursor.

COJA1_HUMAN
NC score	0.053868 (rank : 274)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	288	Target Neighborhood Hits	323	Shared Neighborhood Hits	50
SwissProt Accessions	Q14993, Q00559, Q05850, Q12885, Q13676, Q5JUF0, Q5T424, Q9H572, Q9NPZ2, Q9NQP2	Gene names	COL19A1
Domain Architecture
Description	Collagen alpha-1(XIX) chain precursor (Collagen alpha-1(Y) chain).

RUSC1_MOUSE
NC score	0.053611 (rank : 275)	θ value	6.88961 (rank : 243)
Query Neighborhood Hits	288	Target Neighborhood Hits	206	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BG26, Q6PHT9	Gene names	Rusc1
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1.

SSBP4_HUMAN
NC score	0.053339 (rank : 276)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	288	Target Neighborhood Hits	753	Shared Neighborhood Hits	98
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

CABIN_HUMAN
NC score	0.053236 (rank : 277)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	288	Target Neighborhood Hits	490	Shared Neighborhood Hits	75
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

MYO1F_MOUSE
NC score	0.053194 (rank : 278)	θ value	0.365318 (rank : 58)
Query Neighborhood Hits	288	Target Neighborhood Hits	262	Shared Neighborhood Hits	56
SwissProt Accessions	P70248	Gene names	Myo1f
Domain Architecture
Description	Myosin If.

VAV3_MOUSE
NC score	0.053127 (rank : 279)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	288	Target Neighborhood Hits	404	Shared Neighborhood Hits	58
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

VAV3_HUMAN
NC score	0.052807 (rank : 280)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	288	Target Neighborhood Hits	398	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

FMN1A_MOUSE
NC score	0.052713 (rank : 281)	θ value	2.36792 (rank : 140)
Query Neighborhood Hits	288	Target Neighborhood Hits	423	Shared Neighborhood Hits	43
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

PEX13_MOUSE
NC score	0.052617 (rank : 282)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	288	Target Neighborhood Hits	126	Shared Neighborhood Hits	36
SwissProt Accessions	Q9D0K1, Q3U5T1, Q8CCJ5, Q8CCW5, Q99MM2, Q9EPK1	Gene names	Pex13
Domain Architecture	No domain graphic available
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

SGIP1_MOUSE
NC score	0.052578 (rank : 283)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	288	Target Neighborhood Hits	180	Shared Neighborhood Hits	35
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

NUMB_MOUSE
NC score	0.052572 (rank : 284)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	288	Target Neighborhood Hits	91	Shared Neighborhood Hits	12
SwissProt Accessions	Q9QZS3, P70422, Q8CIB1, Q9DC57, Q9QZR1, Q9QZS4	Gene names	Numb
Domain Architecture
Description	Protein numb homolog (m-Numb) (m-Nb).

CGRE1_HUMAN
NC score	0.052487 (rank : 285)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	288	Target Neighborhood Hits	354	Shared Neighborhood Hits	57
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

SFPQ_MOUSE
NC score	0.052485 (rank : 286)	θ value	5.27518 (rank : 219)
Query Neighborhood Hits	288	Target Neighborhood Hits	958	Shared Neighborhood Hits	64
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

MYO1F_HUMAN
NC score	0.052325 (rank : 287)	θ value	0.62314 (rank : 77)
Query Neighborhood Hits	288	Target Neighborhood Hits	275	Shared Neighborhood Hits	60
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

RIMB2_MOUSE
NC score	0.052323 (rank : 288)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	288	Target Neighborhood Hits	246	Shared Neighborhood Hits	44
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

IRX5_MOUSE
NC score	0.052283 (rank : 289)	θ value	1.81305 (rank : 124)
Query Neighborhood Hits	288	Target Neighborhood Hits	324	Shared Neighborhood Hits	36
SwissProt Accessions	Q9JKQ4, Q80WV4, Q9JLL5	Gene names	Irx5, Irxb2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-5 (Iroquois homeobox protein 5) (Homeodomain protein IRXB2).

K1949_HUMAN
NC score	0.052169 (rank : 290)	θ value	0.62314 (rank : 74)
Query Neighborhood Hits	288	Target Neighborhood Hits	121	Shared Neighborhood Hits	16
SwissProt Accessions	Q6NYC8, Q68CK8, Q6ZUJ6, Q8NDQ4, Q8TF52, Q9BRL9	Gene names	KIAA1949
Domain Architecture	No domain graphic available
Description	Protein KIAA1949.

PRG4_HUMAN
NC score	0.052119 (rank : 291)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	288	Target Neighborhood Hits	764	Shared Neighborhood Hits	62
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

COHA1_HUMAN
NC score	0.052116 (rank : 292)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	288	Target Neighborhood Hits	400	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

ZN598_MOUSE
NC score	0.052022 (rank : 293)	θ value	1.38821 (rank : 114)
Query Neighborhood Hits	288	Target Neighborhood Hits	255	Shared Neighborhood Hits	14
SwissProt Accessions	Q80YR4, Q6KAT0, Q8R3S1	Gene names	Znf598, Zfp598
Domain Architecture	No domain graphic available
Description	Zinc finger protein 598.

CO6A1_MOUSE
NC score	0.051981 (rank : 294)	θ value	3.0926 (rank : 159)
Query Neighborhood Hits	288	Target Neighborhood Hits	241	Shared Neighborhood Hits	43
SwissProt Accessions	Q04857	Gene names	Col6a1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

CDT1_MOUSE
NC score	0.051905 (rank : 295)	θ value	1.06291 (rank : 91)
Query Neighborhood Hits	288	Target Neighborhood Hits	72	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R4E9, Q8BUQ1, Q8BX29, Q8R3V0, Q8R4E8	Gene names	Cdt1, Ris2
Domain Architecture	No domain graphic available
Description	DNA replication factor Cdt1 (Double parked homolog) (DUP) (Retroviral insertion site 2 protein).

MDC1_HUMAN
NC score	0.051880 (rank : 296)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	288	Target Neighborhood Hits	1446	Shared Neighborhood Hits	97
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

CABL2_MOUSE
NC score	0.051790 (rank : 297)	θ value	0.125558 (rank : 38)
Query Neighborhood Hits	288	Target Neighborhood Hits	79	Shared Neighborhood Hits	19
SwissProt Accessions	Q8K3M5	Gene names	Cables2
Domain Architecture
Description	CDK5 and ABL1 enzyme substrate 2 (Interactor with CDK3 2) (Ik3-2).

TCOF_HUMAN
NC score	0.051630 (rank : 298)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	288	Target Neighborhood Hits	543	Shared Neighborhood Hits	53
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

VCY1_HUMAN
NC score	0.051552 (rank : 299)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	288	Target Neighborhood Hits	38	Shared Neighborhood Hits	7
SwissProt Accessions	O14598	Gene names	VCY, BPY1
Domain Architecture	No domain graphic available
Description	Testis-specific basic protein Y 1 (Variably charged protein Y).

ARHG4_HUMAN
NC score	0.051534 (rank : 300)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	288	Target Neighborhood Hits	242	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

CJ078_MOUSE
NC score	0.051529 (rank : 301)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	288	Target Neighborhood Hits	559	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

CONA1_MOUSE
NC score	0.051370 (rank : 302)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	288	Target Neighborhood Hits	254	Shared Neighborhood Hits	52
SwissProt Accessions	Q8K4G2, Q5SUQ0	Gene names	Col23a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

CO6A1_HUMAN
NC score	0.051287 (rank : 303)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	288	Target Neighborhood Hits	264	Shared Neighborhood Hits	47
SwissProt Accessions	P12109, O00117, O00118, Q14040, Q14041, Q16258	Gene names	COL6A1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

ALEX_HUMAN
NC score	0.051074 (rank : 304)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	288	Target Neighborhood Hits	361	Shared Neighborhood Hits	39
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

FYB_HUMAN
NC score	0.050951 (rank : 305)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	288	Target Neighborhood Hits	379	Shared Neighborhood Hits	63
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

APBA3_MOUSE
NC score	0.050425 (rank : 306)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	288	Target Neighborhood Hits	174	Shared Neighborhood Hits	21
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

CT032_HUMAN
NC score	0.050230 (rank : 307)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	288	Target Neighborhood Hits	235	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

CK024_HUMAN
NC score	0.050190 (rank : 308)	θ value	8.99809 (rank : 256)
Query Neighborhood Hits	288	Target Neighborhood Hits	408	Shared Neighborhood Hits	52
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

RIMB1_MOUSE
NC score	0.050148 (rank : 309)	θ value	0.47712 (rank : 68)
Query Neighborhood Hits	288	Target Neighborhood Hits	1376	Shared Neighborhood Hits	91
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

NOLC1_HUMAN
NC score	0.050028 (rank : 310)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	288	Target Neighborhood Hits	452	Shared Neighborhood Hits	36
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

CSKI1_HUMAN
NC score	0.049937 (rank : 311)	θ value	5.27518 (rank : 205)
Query Neighborhood Hits	288	Target Neighborhood Hits	997	Shared Neighborhood Hits	112
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

NASP_HUMAN
NC score	0.049480 (rank : 312)	θ value	2.36792 (rank : 144)
Query Neighborhood Hits	288	Target Neighborhood Hits	709	Shared Neighborhood Hits	32
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

ANK2_HUMAN
NC score	0.049405 (rank : 313)	θ value	0.163984 (rank : 42)
Query Neighborhood Hits	288	Target Neighborhood Hits	1615	Shared Neighborhood Hits	113
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

SHC2_MOUSE
NC score	0.048785 (rank : 314)	θ value	2.36792 (rank : 153)
Query Neighborhood Hits	288	Target Neighborhood Hits	144	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BMC3	Gene names	Shc2, Sck, ShcB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck) (Protein Sli).

MAP1A_HUMAN
NC score	0.048622 (rank : 315)	θ value	6.88961 (rank : 235)
Query Neighborhood Hits	288	Target Neighborhood Hits	1626	Shared Neighborhood Hits	114
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

CO8A2_HUMAN
NC score	0.047917 (rank : 316)	θ value	6.88961 (rank : 230)
Query Neighborhood Hits	288	Target Neighborhood Hits	299	Shared Neighborhood Hits	51
SwissProt Accessions	P25067, Q8TEJ5	Gene names	COL8A2
Domain Architecture
Description	Collagen alpha-2(VIII) chain precursor (Endothelial collagen).

LEO1_HUMAN
NC score	0.047272 (rank : 317)	θ value	5.27518 (rank : 213)
Query Neighborhood Hits	288	Target Neighborhood Hits	958	Shared Neighborhood Hits	35
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

MTSS1_MOUSE
NC score	0.046700 (rank : 318)	θ value	8.99809 (rank : 267)
Query Neighborhood Hits	288	Target Neighborhood Hits	592	Shared Neighborhood Hits	80
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

CO8A1_HUMAN
NC score	0.046333 (rank : 319)	θ value	3.0926 (rank : 160)
Query Neighborhood Hits	288	Target Neighborhood Hits	288	Shared Neighborhood Hits	47
SwissProt Accessions	P27658, Q96D07	Gene names	COL8A1
Domain Architecture
Description	Collagen alpha-1(VIII) chain precursor (Endothelial collagen).

P85B_HUMAN
NC score	0.046189 (rank : 320)	θ value	8.99809 (rank : 269)
Query Neighborhood Hits	288	Target Neighborhood Hits	543	Shared Neighborhood Hits	41
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

EMID1_MOUSE
NC score	0.045834 (rank : 321)	θ value	8.99809 (rank : 262)
Query Neighborhood Hits	288	Target Neighborhood Hits	230	Shared Neighborhood Hits	41
SwissProt Accessions	Q91VF5	Gene names	Emid1, Emu1
Domain Architecture	No domain graphic available
Description	EMI domain-containing protein 1 precursor (Protein Emu1) (Emilin and multimerin domain-containing protein 1).

GON4L_HUMAN
NC score	0.045833 (rank : 322)	θ value	0.813845 (rank : 83)
Query Neighborhood Hits	288	Target Neighborhood Hits	555	Shared Neighborhood Hits	46
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

DOT1L_HUMAN
NC score	0.044616 (rank : 323)	θ value	5.27518 (rank : 206)
Query Neighborhood Hits	288	Target Neighborhood Hits	660	Shared Neighborhood Hits	59
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

BIM_HUMAN
NC score	0.044330 (rank : 324)	θ value	3.0926 (rank : 157)
Query Neighborhood Hits	288	Target Neighborhood Hits	134	Shared Neighborhood Hits	33
SwissProt Accessions	O43521, O43522	Gene names	BCL2L11, BIM
Domain Architecture
Description	Bcl-2-like protein 11 (Bcl2-interacting mediator of cell death).

CO8A1_MOUSE
NC score	0.044321 (rank : 325)	θ value	6.88961 (rank : 229)
Query Neighborhood Hits	288	Target Neighborhood Hits	251	Shared Neighborhood Hits	45
SwissProt Accessions	Q00780, Q9D2V4	Gene names	Col8a1
Domain Architecture
Description	Collagen alpha-1(VIII) chain precursor.

VASP_HUMAN
NC score	0.043994 (rank : 326)	θ value	5.27518 (rank : 222)
Query Neighborhood Hits	288	Target Neighborhood Hits	201	Shared Neighborhood Hits	35
SwissProt Accessions	P50552, Q6PIZ1, Q93035	Gene names	VASP
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

TTC15_HUMAN
NC score	0.043939 (rank : 327)	θ value	4.03905 (rank : 197)
Query Neighborhood Hits	288	Target Neighborhood Hits	112	Shared Neighborhood Hits	22
SwissProt Accessions	Q8WVT3, Q8WVW1, Q9Y395	Gene names	TTC15
Domain Architecture
Description	Tetratricopeptide repeat protein 15 (TPR repeat protein 15).

COEA1_HUMAN
NC score	0.043624 (rank : 328)	θ value	8.99809 (rank : 259)
Query Neighborhood Hits	288	Target Neighborhood Hits	427	Shared Neighborhood Hits	52
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

UBP42_HUMAN
NC score	0.042809 (rank : 329)	θ value	0.365318 (rank : 62)
Query Neighborhood Hits	288	Target Neighborhood Hits	445	Shared Neighborhood Hits	60
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

P85B_MOUSE
NC score	0.042742 (rank : 330)	θ value	8.99809 (rank : 270)
Query Neighborhood Hits	288	Target Neighborhood Hits	519	Shared Neighborhood Hits	37
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

NHS_HUMAN
NC score	0.042713 (rank : 331)	θ value	4.03905 (rank : 193)
Query Neighborhood Hits	288	Target Neighborhood Hits	198	Shared Neighborhood Hits	19
SwissProt Accessions	Q6T4R5, Q5J7Q0, Q5J7Q1, Q68DR5	Gene names	NHS
Domain Architecture	No domain graphic available
Description	Nance-Horan syndrome protein (Congenital cataracts and dental anomalies protein).

CLIC6_HUMAN
NC score	0.042618 (rank : 332)	θ value	2.36792 (rank : 136)
Query Neighborhood Hits	288	Target Neighborhood Hits	289	Shared Neighborhood Hits	50
SwissProt Accessions	Q96NY7, Q8IX31	Gene names	CLIC6, CLIC1L
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel 6.

DCC_MOUSE
NC score	0.042211 (rank : 333)	θ value	0.00228821 (rank : 12)
Query Neighborhood Hits	288	Target Neighborhood Hits	896	Shared Neighborhood Hits	53
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

ANR11_HUMAN
NC score	0.040969 (rank : 334)	θ value	5.27518 (rank : 199)
Query Neighborhood Hits	288	Target Neighborhood Hits	1289	Shared Neighborhood Hits	83
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

PGCA_HUMAN
NC score	0.040877 (rank : 335)	θ value	8.99809 (rank : 271)
Query Neighborhood Hits	288	Target Neighborhood Hits	821	Shared Neighborhood Hits	59
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

CENG1_MOUSE
NC score	0.040840 (rank : 336)	θ value	1.81305 (rank : 118)
Query Neighborhood Hits	288	Target Neighborhood Hits	531	Shared Neighborhood Hits	39
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

RTN4_MOUSE
NC score	0.040509 (rank : 337)	θ value	3.0926 (rank : 173)
Query Neighborhood Hits	288	Target Neighborhood Hits	341	Shared Neighborhood Hits	32
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

COCA1_HUMAN
NC score	0.038919 (rank : 338)	θ value	2.36792 (rank : 139)
Query Neighborhood Hits	288	Target Neighborhood Hits	458	Shared Neighborhood Hits	46
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

TCAL5_HUMAN
NC score	0.038825 (rank : 339)	θ value	8.99809 (rank : 285)
Query Neighborhood Hits	288	Target Neighborhood Hits	806	Shared Neighborhood Hits	52
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

EVL_HUMAN
NC score	0.038259 (rank : 340)	θ value	3.0926 (rank : 161)
Query Neighborhood Hits	288	Target Neighborhood Hits	260	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UI08, O95884, Q7Z522, Q8TBV1, Q9UF25, Q9UIC2	Gene names	EVL, RNB6
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

JPH2_MOUSE
NC score	0.038075 (rank : 341)	θ value	5.27518 (rank : 211)
Query Neighborhood Hits	288	Target Neighborhood Hits	279	Shared Neighborhood Hits	43
SwissProt Accessions	Q9ET78, Q9ET79	Gene names	Jph2, Jp2
Domain Architecture	No domain graphic available
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

BAZ2A_HUMAN
NC score	0.038026 (rank : 342)	θ value	1.38821 (rank : 102)
Query Neighborhood Hits	288	Target Neighborhood Hits	780	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

COCA1_MOUSE
NC score	0.037948 (rank : 343)	θ value	8.99809 (rank : 258)
Query Neighborhood Hits	288	Target Neighborhood Hits	467	Shared Neighborhood Hits	54
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

IF35_MOUSE
NC score	0.037933 (rank : 344)	θ value	8.99809 (rank : 266)
Query Neighborhood Hits	288	Target Neighborhood Hits	210	Shared Neighborhood Hits	27
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

JIP3_HUMAN
NC score	0.037826 (rank : 345)	θ value	1.06291 (rank : 95)
Query Neighborhood Hits	288	Target Neighborhood Hits	1039	Shared Neighborhood Hits	76
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

NEST_HUMAN
NC score	0.037567 (rank : 346)	θ value	1.81305 (rank : 127)
Query Neighborhood Hits	288	Target Neighborhood Hits	1305	Shared Neighborhood Hits	83
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

TXLNB_HUMAN
NC score	0.036914 (rank : 347)	θ value	0.163984 (rank : 44)
Query Neighborhood Hits	288	Target Neighborhood Hits	912	Shared Neighborhood Hits	67
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

CQ028_MOUSE
NC score	0.036737 (rank : 348)	θ value	1.38821 (rank : 105)
Query Neighborhood Hits	288	Target Neighborhood Hits	54	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R1F6, Q8C8V6	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C17orf28 homolog.

DMN_HUMAN
NC score	0.036577 (rank : 349)	θ value	0.365318 (rank : 56)
Query Neighborhood Hits	288	Target Neighborhood Hits	690	Shared Neighborhood Hits	34
SwissProt Accessions	O15061	Gene names	DMN, KIAA0353
Domain Architecture
Description	Desmuslin.

CENG1_HUMAN
NC score	0.035790 (rank : 350)	θ value	2.36792 (rank : 135)
Query Neighborhood Hits	288	Target Neighborhood Hits	544	Shared Neighborhood Hits	37
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

YTHD1_HUMAN
NC score	0.035558 (rank : 351)	θ value	1.38821 (rank : 113)
Query Neighborhood Hits	288	Target Neighborhood Hits	71	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BYJ9, Q8N3G5, Q8TBT1, Q96AN4, Q96S57, Q9BTI7, Q9NX79	Gene names	YTHDF1, C20orf21
Domain Architecture
Description	YTH domain family protein 1 (Dermatomyositis associated with cancer putative autoantigen 1) (DACA-1).

ZN414_HUMAN
NC score	0.035468 (rank : 352)	θ value	0.279714 (rank : 54)
Query Neighborhood Hits	288	Target Neighborhood Hits	548	Shared Neighborhood Hits	15
SwissProt Accessions	Q96IQ9	Gene names	ZNF414
Domain Architecture	No domain graphic available
Description	Zinc finger protein 414.

PDCD7_HUMAN
NC score	0.032931 (rank : 353)	θ value	6.88961 (rank : 239)
Query Neighborhood Hits	288	Target Neighborhood Hits	255	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N8D1, Q96AK8, Q9Y6D7	Gene names	PDCD7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18) (HES18).

RP3A_MOUSE
NC score	0.032785 (rank : 354)	θ value	6.88961 (rank : 242)
Query Neighborhood Hits	288	Target Neighborhood Hits	510	Shared Neighborhood Hits	65
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

CQ028_HUMAN
NC score	0.032145 (rank : 355)	θ value	4.03905 (rank : 183)
Query Neighborhood Hits	288	Target Neighborhood Hits	56	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IV36, Q8N5L6, Q8TE83, Q9NT34	Gene names	C17orf28, DMC1
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C17orf28 (Down-regulated in multiple cancers- 1).

MEF2B_HUMAN
NC score	0.032041 (rank : 356)	θ value	2.36792 (rank : 143)
Query Neighborhood Hits	288	Target Neighborhood Hits	150	Shared Neighborhood Hits	29
SwissProt Accessions	Q02080	Gene names	MEF2B, XMEF2
Domain Architecture
Description	Myocyte-specific enhancer factor 2B (Serum response factor-like protein 2) (XMEF2) (RSRFR2).

RP3A_HUMAN
NC score	0.031331 (rank : 357)	θ value	4.03905 (rank : 195)
Query Neighborhood Hits	288	Target Neighborhood Hits	305	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

GP153_HUMAN
NC score	0.031075 (rank : 358)	θ value	0.365318 (rank : 57)
Query Neighborhood Hits	288	Target Neighborhood Hits	332	Shared Neighborhood Hits	18
SwissProt Accessions	Q6NV75, Q5TGR5, Q6AHW8, Q86SP8	Gene names	GPR153, PGR1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 153 (G-protein coupled receptor PGR1).

INVS_MOUSE
NC score	0.030693 (rank : 359)	θ value	6.88961 (rank : 234)
Query Neighborhood Hits	288	Target Neighborhood Hits	609	Shared Neighborhood Hits	53
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

SPEG_HUMAN
NC score	0.030662 (rank : 360)	θ value	0.365318 (rank : 61)
Query Neighborhood Hits	288	Target Neighborhood Hits	1762	Shared Neighborhood Hits	99
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

GPR88_MOUSE
NC score	0.029959 (rank : 361)	θ value	0.813845 (rank : 84)
Query Neighborhood Hits	288	Target Neighborhood Hits	170	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EPB7	Gene names	Gpr88, Strg
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 88 (Striatum-specific G-protein coupled receptor).

TCAL3_HUMAN
NC score	0.029910 (rank : 362)	θ value	6.88961 (rank : 247)
Query Neighborhood Hits	288	Target Neighborhood Hits	274	Shared Neighborhood Hits	18
SwissProt Accessions	Q969E4	Gene names	TCEAL3
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 3 (TCEA-like protein 3) (Transcription elongation factor S-II protein-like 3).

CEND3_HUMAN
NC score	0.029384 (rank : 363)	θ value	2.36792 (rank : 134)
Query Neighborhood Hits	288	Target Neighborhood Hits	275	Shared Neighborhood Hits	25
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

HCN2_HUMAN
NC score	0.029283 (rank : 364)	θ value	4.03905 (rank : 187)
Query Neighborhood Hits	288	Target Neighborhood Hits	369	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

CAC1G_HUMAN
NC score	0.029208 (rank : 365)	θ value	2.36792 (rank : 133)
Query Neighborhood Hits	288	Target Neighborhood Hits	587	Shared Neighborhood Hits	82
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

INCE_HUMAN
NC score	0.028984 (rank : 366)	θ value	0.125558 (rank : 40)
Query Neighborhood Hits	288	Target Neighborhood Hits	978	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

LRC50_HUMAN
NC score	0.028773 (rank : 367)	θ value	5.27518 (rank : 214)
Query Neighborhood Hits	288	Target Neighborhood Hits	275	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NEP3, Q69YI8, Q69YJ0, Q96LP3	Gene names	LRRC50
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 50.

MAP9_MOUSE
NC score	0.028772 (rank : 368)	θ value	3.0926 (rank : 163)
Query Neighborhood Hits	288	Target Neighborhood Hits	529	Shared Neighborhood Hits	25
SwissProt Accessions	Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7	Gene names	Map9, Asap
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

PRGC2_MOUSE
NC score	0.028490 (rank : 369)	θ value	2.36792 (rank : 148)
Query Neighborhood Hits	288	Target Neighborhood Hits	225	Shared Neighborhood Hits	19
SwissProt Accessions	Q8VHJ7, Q8C1C0	Gene names	Ppargc1b, Errl1, Pgc1, Pgc1b, Ppargc1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta protein) (PGC-1beta) (ERR ligand 1) (PPARGC-1-beta) (PGC-1-beta).

EPN3_MOUSE
NC score	0.028448 (rank : 370)	θ value	5.27518 (rank : 208)
Query Neighborhood Hits	288	Target Neighborhood Hits	312	Shared Neighborhood Hits	49
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

COG8_MOUSE
NC score	0.028197 (rank : 371)	θ value	5.27518 (rank : 204)
Query Neighborhood Hits	288	Target Neighborhood Hits	147	Shared Neighborhood Hits	21
SwissProt Accessions	Q9JJA2	Gene names	Cog8
Domain Architecture
Description	Conserved oligomeric Golgi complex component 8.

SIG12_MOUSE
NC score	0.027877 (rank : 372)	θ value	0.813845 (rank : 88)
Query Neighborhood Hits	288	Target Neighborhood Hits	225	Shared Neighborhood Hits	7
SwissProt Accessions	Q91Y57	Gene names	Siglec12, Siglec5, Siglece, Siglecl1
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 12 precursor (Siglec-12) (Sialic acid-binding Ig-like lectin-like 1) (Siglec-L1) (Sialic acid-binding Ig-like lectin 5) (Siglec-5) (mSiglec-E) (Myeloid inhibitory siglec) (MIS).

ZDHC8_MOUSE
NC score	0.027808 (rank : 373)	θ value	1.06291 (rank : 101)
Query Neighborhood Hits	288	Target Neighborhood Hits	243	Shared Neighborhood Hits	44
SwissProt Accessions	Q5Y5T5, Q7TNF7	Gene names	Zdhhc8
Domain Architecture	No domain graphic available
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8).

CC47_MOUSE
NC score	0.027286 (rank : 374)	θ value	1.81305 (rank : 117)
Query Neighborhood Hits	288	Target Neighborhood Hits	245	Shared Neighborhood Hits	12
SwissProt Accessions	Q9D024, Q3TSB5, Q3V1S7, Q8C5D9, Q920S6	Gene names	Ccdc47, Asp4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor (Adipocyte-specific protein 4).

SPEG_MOUSE
NC score	0.027210 (rank : 375)	θ value	3.0926 (rank : 174)
Query Neighborhood Hits	288	Target Neighborhood Hits	1959	Shared Neighborhood Hits	106
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SC24D_HUMAN
NC score	0.027196 (rank : 376)	θ value	4.03905 (rank : 196)
Query Neighborhood Hits	288	Target Neighborhood Hits	173	Shared Neighborhood Hits	27
SwissProt Accessions	O94855	Gene names	SEC24D, KIAA0755
Domain Architecture
Description	Protein transport protein Sec24D (SEC24-related protein D).

MELPH_HUMAN
NC score	0.027129 (rank : 377)	θ value	3.0926 (rank : 164)
Query Neighborhood Hits	288	Target Neighborhood Hits	145	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BV36, Q9HA71	Gene names	MLPH, SLAC2A
Domain Architecture	No domain graphic available
Description	Melanophilin (Exophilin-3) (Synaptotagmin-like protein 2a) (Slp homolog lacking C2 domains a).

ZMYM3_HUMAN
NC score	0.026224 (rank : 378)	θ value	6.88961 (rank : 251)
Query Neighborhood Hits	288	Target Neighborhood Hits	223	Shared Neighborhood Hits	27
SwissProt Accessions	Q14202, O15089	Gene names	ZMYM3, DXS6673E, KIAA0385, ZNF261
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 3 (Zinc finger protein 261).

SPAT2_HUMAN
NC score	0.025470 (rank : 379)	θ value	5.27518 (rank : 221)
Query Neighborhood Hits	288	Target Neighborhood Hits	39	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UM82, O94857	Gene names	SPATA2, KIAA0757, PD1
Domain Architecture	No domain graphic available
Description	Spermatogenesis-associated protein 2 (Spermatogenesis-associated protein PD1).

OPHN1_MOUSE
NC score	0.025444 (rank : 380)	θ value	2.36792 (rank : 146)
Query Neighborhood Hits	288	Target Neighborhood Hits	174	Shared Neighborhood Hits	15
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

MYCL1_MOUSE
NC score	0.025328 (rank : 381)	θ value	3.0926 (rank : 165)
Query Neighborhood Hits	288	Target Neighborhood Hits	123	Shared Neighborhood Hits	14
SwissProt Accessions	P10166, Q5FWI7	Gene names	Mycl1, Lmyc1, Mycl
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

IQEC2_HUMAN
NC score	0.024577 (rank : 382)	θ value	1.81305 (rank : 123)
Query Neighborhood Hits	288	Target Neighborhood Hits	403	Shared Neighborhood Hits	33
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

ACK1_HUMAN
NC score	0.024414 (rank : 383)	θ value	0.62314 (rank : 69)
Query Neighborhood Hits	288	Target Neighborhood Hits	1140	Shared Neighborhood Hits	72
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

TTBK1_HUMAN
NC score	0.024029 (rank : 384)	θ value	0.62314 (rank : 80)
Query Neighborhood Hits	288	Target Neighborhood Hits	1058	Shared Neighborhood Hits	61
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

ACK1_MOUSE
NC score	0.023637 (rank : 385)	θ value	0.62314 (rank : 70)
Query Neighborhood Hits	288	Target Neighborhood Hits	1080	Shared Neighborhood Hits	72
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

NFIA_HUMAN
NC score	0.023306 (rank : 386)	θ value	3.0926 (rank : 166)
Query Neighborhood Hits	288	Target Neighborhood Hits	65	Shared Neighborhood Hits	16
SwissProt Accessions	Q12857, Q9H3X9, Q9P2A9	Gene names	NFIA, KIAA1439
Domain Architecture
Description	Nuclear factor 1 A-type (Nuclear factor 1/A) (NF1-A) (NFI-A) (NF-I/A) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

PTN23_HUMAN
NC score	0.022795 (rank : 387)	θ value	8.99809 (rank : 275)
Query Neighborhood Hits	288	Target Neighborhood Hits	646	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

RPGR_HUMAN
NC score	0.022489 (rank : 388)	θ value	2.36792 (rank : 150)
Query Neighborhood Hits	288	Target Neighborhood Hits	279	Shared Neighborhood Hits	18
SwissProt Accessions	Q92834, O00702, O00737, Q8N5T6, Q93039, Q9HD29, Q9UMR1	Gene names	RPGR, RP3, XLRP3
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator.

NFIA_MOUSE
NC score	0.022312 (rank : 389)	θ value	4.03905 (rank : 192)
Query Neighborhood Hits	288	Target Neighborhood Hits	69	Shared Neighborhood Hits	16
SwissProt Accessions	Q02780, P70250, P70251, Q3UUZ2, Q61960, Q8VBT5, Q9R1G5	Gene names	Nfia
Domain Architecture
Description	Nuclear factor 1 A-type (Nuclear factor 1/A) (NF1-A) (NFI-A) (NF-I/A) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

X3CL1_HUMAN
NC score	0.021808 (rank : 390)	θ value	5.27518 (rank : 224)
Query Neighborhood Hits	288	Target Neighborhood Hits	152	Shared Neighborhood Hits	18
SwissProt Accessions	P78423, O00672	Gene names	CX3CL1, A-152E5.2, FKN, NTT, SCYD1
Domain Architecture
Description	Fractalkine precursor (CX3CL1) (Neurotactin) (CX3C membrane-anchored chemokine) (Small inducible cytokine D1).

SI1L3_HUMAN
NC score	0.020801 (rank : 391)	θ value	2.36792 (rank : 154)
Query Neighborhood Hits	288	Target Neighborhood Hits	305	Shared Neighborhood Hits	30
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

TERF2_MOUSE
NC score	0.020667 (rank : 392)	θ value	6.88961 (rank : 248)
Query Neighborhood Hits	288	Target Neighborhood Hits	128	Shared Neighborhood Hits	11
SwissProt Accessions	O35144	Gene names	Terf2, Trf2
Domain Architecture
Description	Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein).

FCN1_MOUSE
NC score	0.020127 (rank : 393)	θ value	6.88961 (rank : 232)
Query Neighborhood Hits	288	Target Neighborhood Hits	173	Shared Neighborhood Hits	29
SwissProt Accessions	O70165	Gene names	Fcn1, Fcna
Domain Architecture
Description	Ficolin-1 precursor (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin A) (M-Ficolin).

RGS14_HUMAN
NC score	0.019944 (rank : 394)	θ value	5.27518 (rank : 218)
Query Neighborhood Hits	288	Target Neighborhood Hits	77	Shared Neighborhood Hits	8
SwissProt Accessions	O43566, O43565, Q8TD62	Gene names	RGS14
Domain Architecture
Description	Regulator of G-protein signaling 14 (RGS14).

EP15_HUMAN
NC score	0.019875 (rank : 395)	θ value	0.62314 (rank : 73)
Query Neighborhood Hits	288	Target Neighborhood Hits	1021	Shared Neighborhood Hits	29
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

TMC8_HUMAN
NC score	0.019527 (rank : 396)	θ value	2.36792 (rank : 155)
Query Neighborhood Hits	288	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IU68, Q8IWU7, Q8N358, Q8NF04	Gene names	TMC8, EVER2, EVIN2
Domain Architecture	No domain graphic available
Description	Transmembrane channel-like protein 8 (Epidermodysplasia verruciformis protein 2).

CF051_HUMAN
NC score	0.019412 (rank : 397)	θ value	8.99809 (rank : 255)
Query Neighborhood Hits	288	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q969F1	Gene names	C6orf51
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf51.

IKBE_MOUSE
NC score	0.019344 (rank : 398)	θ value	6.88961 (rank : 233)
Query Neighborhood Hits	288	Target Neighborhood Hits	308	Shared Neighborhood Hits	18
SwissProt Accessions	O54910, Q3U686, Q9CZZ9, Q9D7U3	Gene names	Nfkbie, Ikbe
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKB-E).

ZC3H6_MOUSE
NC score	0.018886 (rank : 399)	θ value	6.88961 (rank : 250)
Query Neighborhood Hits	288	Target Neighborhood Hits	239	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BYK8, Q80UK3, Q8C1H1, Q9D604	Gene names	Zc3h6, Zc3hdc6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

GAK_HUMAN
NC score	0.018811 (rank : 400)	θ value	0.279714 (rank : 49)
Query Neighborhood Hits	288	Target Neighborhood Hits	1028	Shared Neighborhood Hits	50
SwissProt Accessions	O14976, Q9BVY6	Gene names	GAK
Domain Architecture
Description	Cyclin G-associated kinase (EC 2.7.11.1).

DUET_HUMAN
NC score	0.018708 (rank : 401)	θ value	0.163984 (rank : 43)
Query Neighborhood Hits	288	Target Neighborhood Hits	1220	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

GPR88_HUMAN
NC score	0.018678 (rank : 402)	θ value	8.99809 (rank : 263)
Query Neighborhood Hits	288	Target Neighborhood Hits	172	Shared Neighborhood Hits	3
SwissProt Accessions	Q9GZN0, Q6VN48	Gene names	GPR88, STRG
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 88 (Striatum-specific G-protein coupled receptor).

DTX1_MOUSE
NC score	0.018589 (rank : 403)	θ value	5.27518 (rank : 207)
Query Neighborhood Hits	288	Target Neighborhood Hits	99	Shared Neighborhood Hits	14
SwissProt Accessions	Q61010, Q3TER5, Q8C2H2, Q9ER09	Gene names	Dtx1
Domain Architecture
Description	Protein deltex-1 (Deltex-1) (Deltex1) (mDTX1) (FXI-T1).

GP152_HUMAN
NC score	0.018513 (rank : 404)	θ value	5.27518 (rank : 209)
Query Neighborhood Hits	288	Target Neighborhood Hits	636	Shared Neighborhood Hits	38
SwissProt Accessions	Q8TDT2, Q86SM0	Gene names	GPR152, PGR5
Domain Architecture
Description	Probable G-protein coupled receptor 152 (G-protein coupled receptor PGR5).

NFIC_HUMAN
NC score	0.018355 (rank : 405)	θ value	8.99809 (rank : 268)
Query Neighborhood Hits	288	Target Neighborhood Hits	59	Shared Neighborhood Hits	9
SwissProt Accessions	P08651, P08652, Q14932, Q9UPJ3, Q9UPJ9, Q9UPK0, Q9UPK1	Gene names	NFIC, NFI
Domain Architecture
Description	Nuclear factor 1 C-type (Nuclear factor 1/C) (NF1-C) (NFI-C) (NF-I/C) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

SEZ6L_HUMAN
NC score	0.018182 (rank : 406)	θ value	8.99809 (rank : 277)
Query Neighborhood Hits	288	Target Neighborhood Hits	289	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

PCNT_HUMAN
NC score	0.017277 (rank : 407)	θ value	6.88961 (rank : 238)
Query Neighborhood Hits	288	Target Neighborhood Hits	1551	Shared Neighborhood Hits	69
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

HES6_HUMAN
NC score	0.016802 (rank : 408)	θ value	4.03905 (rank : 188)
Query Neighborhood Hits	288	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	Q96HZ4, Q8N2J2, Q96T93, Q9P2S3	Gene names	HES6
Domain Architecture	No domain graphic available
Description	Transcription cofactor HES-6 (Hairy and enhancer of split 6) (C- HAIRY1).

SYTL1_MOUSE
NC score	0.016448 (rank : 409)	θ value	6.88961 (rank : 246)
Query Neighborhood Hits	288	Target Neighborhood Hits	314	Shared Neighborhood Hits	21
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

OSBL8_HUMAN
NC score	0.016411 (rank : 410)	θ value	1.81305 (rank : 128)
Query Neighborhood Hits	288	Target Neighborhood Hits	289	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

HXA3_HUMAN
NC score	0.016246 (rank : 411)	θ value	5.27518 (rank : 210)
Query Neighborhood Hits	288	Target Neighborhood Hits	535	Shared Neighborhood Hits	37
SwissProt Accessions	O43365	Gene names	HOXA3, HOX1E
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1E).

TXK_MOUSE
NC score	0.015388 (rank : 412)	θ value	4.03905 (rank : 198)
Query Neighborhood Hits	288	Target Neighborhood Hits	980	Shared Neighborhood Hits	56
SwissProt Accessions	P42682	Gene names	Txk, Rlk
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18) (Resting lymphocyte kinase).

SSPO_MOUSE
NC score	0.014738 (rank : 413)	θ value	0.21417 (rank : 48)
Query Neighborhood Hits	288	Target Neighborhood Hits	800	Shared Neighborhood Hits	21
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

ADPGK_HUMAN
NC score	0.014415 (rank : 414)	θ value	6.88961 (rank : 225)
Query Neighborhood Hits	288	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BRR6, Q8NBI1, Q8WZ90, Q96NF8, Q9H0A7	Gene names	ADPGK
Domain Architecture	No domain graphic available
Description	ADP-dependent glucokinase (EC 2.7.1.147) (ADPGK) (ADP-GK) (RbBP-35).

SEM6C_MOUSE
NC score	0.013889 (rank : 415)	θ value	6.88961 (rank : 245)
Query Neighborhood Hits	288	Target Neighborhood Hits	352	Shared Neighborhood Hits	59
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

RN167_HUMAN
NC score	0.013685 (rank : 416)	θ value	3.0926 (rank : 172)
Query Neighborhood Hits	288	Target Neighborhood Hits	157	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H6Y7, Q6XYE0, Q8NDC1, Q9Y3V1	Gene names	RNF167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

LIMD1_HUMAN
NC score	0.013340 (rank : 417)	θ value	4.03905 (rank : 191)
Query Neighborhood Hits	288	Target Neighborhood Hits	201	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UGP4, Q9BQQ9, Q9NQ47	Gene names	LIMD1
Domain Architecture
Description	LIM domain-containing protein 1.

TPOR_HUMAN
NC score	0.013041 (rank : 418)	θ value	6.88961 (rank : 249)
Query Neighborhood Hits	288	Target Neighborhood Hits	70	Shared Neighborhood Hits	4
SwissProt Accessions	P40238	Gene names	MPL, TPOR
Domain Architecture
Description	Thrombopoietin receptor precursor (TPO-R) (Myeloproliferative leukemia protein) (C-mpl) (CD110 antigen).

PO6F1_MOUSE
NC score	0.012821 (rank : 419)	θ value	3.0926 (rank : 170)
Query Neighborhood Hits	288	Target Neighborhood Hits	581	Shared Neighborhood Hits	32
SwissProt Accessions	Q07916, Q91XK3	Gene names	Pou6f1, Emb
Domain Architecture
Description	POU domain, class 6, transcription factor 1 (Octamer-binding transcription factor EMB) (Transcription regulatory protein MCP-1).

CAC1E_MOUSE
NC score	0.012407 (rank : 420)	θ value	8.99809 (rank : 254)
Query Neighborhood Hits	288	Target Neighborhood Hits	167	Shared Neighborhood Hits	11
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

LPHN1_HUMAN
NC score	0.012207 (rank : 421)	θ value	0.62314 (rank : 75)
Query Neighborhood Hits	288	Target Neighborhood Hits	155	Shared Neighborhood Hits	9
SwissProt Accessions	O94910, Q96IE7, Q9BU07, Q9HAR3	Gene names	LPHN1, KIAA0821, LEC2
Domain Architecture
Description	Latrophilin-1 precursor (Calcium-independent alpha-latrotoxin receptor 1) (Lectomedin-2).

KCNH2_MOUSE
NC score	0.010537 (rank : 422)	θ value	4.03905 (rank : 190)
Query Neighborhood Hits	288	Target Neighborhood Hits	165	Shared Neighborhood Hits	11
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

MK07_HUMAN
NC score	0.010232 (rank : 423)	θ value	1.38821 (rank : 108)
Query Neighborhood Hits	288	Target Neighborhood Hits	1087	Shared Neighborhood Hits	48
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

VCIP1_MOUSE
NC score	0.010190 (rank : 424)	θ value	8.99809 (rank : 287)
Query Neighborhood Hits	288	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CDG3, Q7TMU9, Q8BP90	Gene names	Vcpip1, Vcip135
Domain Architecture
Description	Deubiquitinating protein VCIP135 (EC 3.4.22.-) (Valosin-containing protein p97/p47 complex-interacting protein p135) (Valosin-containing protein p97/p47 complex-interacting protein 1).

KIF4A_MOUSE
NC score	0.009925 (rank : 425)	θ value	5.27518 (rank : 212)
Query Neighborhood Hits	288	Target Neighborhood Hits	1033	Shared Neighborhood Hits	35
SwissProt Accessions	P33174	Gene names	Kif4a, Kif4, Kns4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

CAC1C_MOUSE
NC score	0.009811 (rank : 426)	θ value	4.03905 (rank : 180)
Query Neighborhood Hits	288	Target Neighborhood Hits	130	Shared Neighborhood Hits	10
SwissProt Accessions	Q01815, Q04476, Q61242, Q99242	Gene names	Cacna1c, Cach2, Cacn2, Cacnl1a1, Cchl1a1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Mouse brain class C) (MBC) (MELC-CC).

MAST3_HUMAN
NC score	0.008806 (rank : 427)	θ value	6.88961 (rank : 236)
Query Neighborhood Hits	288	Target Neighborhood Hits	1128	Shared Neighborhood Hits	45
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

FZD8_MOUSE
NC score	0.008680 (rank : 428)	θ value	4.03905 (rank : 186)
Query Neighborhood Hits	288	Target Neighborhood Hits	89	Shared Neighborhood Hits	7
SwissProt Accessions	Q61091	Gene names	Fzd8
Domain Architecture
Description	Frizzled-8 precursor (Fz-8) (mFz8).

HXD3_MOUSE
NC score	0.007623 (rank : 429)	θ value	4.03905 (rank : 189)
Query Neighborhood Hits	288	Target Neighborhood Hits	435	Shared Neighborhood Hits	17
SwissProt Accessions	P09027, Q3UUD3	Gene names	Hoxd3, Hox-4.1, Hoxd-3
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4.1) (Homeobox protein MH-19).

HXD3_HUMAN
NC score	0.007589 (rank : 430)	θ value	8.99809 (rank : 265)
Query Neighborhood Hits	288	Target Neighborhood Hits	433	Shared Neighborhood Hits	22
SwissProt Accessions	P31249, Q99955, Q9BSC5	Gene names	HOXD3, HOX4A
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4A).

ECHP_HUMAN
NC score	0.007481 (rank : 431)	θ value	8.99809 (rank : 261)
Query Neighborhood Hits	288	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q08426	Gene names	EHHADH, ECHD
Domain Architecture
Description	Peroxisomal bifunctional enzyme (PBE) (PBFE) [Includes: Enoyl-CoA hydratase (EC 4.2.1.17); 3,2-trans-enoyl-CoA isomerase (EC 5.3.3.8); 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35)].

NGN2_MOUSE
NC score	0.007397 (rank : 432)	θ value	6.88961 (rank : 237)
Query Neighborhood Hits	288	Target Neighborhood Hits	106	Shared Neighborhood Hits	6
SwissProt Accessions	P70447, P70237	Gene names	Neurog2, Ath4a, Atoh4, Ngn2
Domain Architecture
Description	Neurogenin 2 (Atonal protein homolog 4) (Helix-loop-helix protein mATH-4A) (MATH4A).

RXRB_MOUSE
NC score	0.007344 (rank : 433)	θ value	6.88961 (rank : 244)
Query Neighborhood Hits	288	Target Neighborhood Hits	230	Shared Neighborhood Hits	21
SwissProt Accessions	P28704, P33243	Gene names	Rxrb, Nr2b2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta) (MHC class I regulatory element-binding protein H-2RIIBP).

PRGR_HUMAN
NC score	0.006962 (rank : 434)	θ value	5.27518 (rank : 217)
Query Neighborhood Hits	288	Target Neighborhood Hits	163	Shared Neighborhood Hits	11
SwissProt Accessions	P06401, Q9UPF7	Gene names	PGR, NR3C3
Domain Architecture
Description	Progesterone receptor (PR).

SRPK1_MOUSE
NC score	0.006539 (rank : 435)	θ value	8.99809 (rank : 281)
Query Neighborhood Hits	288	Target Neighborhood Hits	639	Shared Neighborhood Hits	13
SwissProt Accessions	O70551, O70193, Q99JT3	Gene names	Srpk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SRPK1 (EC 2.7.11.1) (Serine/arginine- rich protein-specific kinase 1) (SR-protein-specific kinase 1) (SFRS protein kinase 1).

AP2A2_MOUSE
NC score	0.005522 (rank : 436)	θ value	8.99809 (rank : 253)
Query Neighborhood Hits	288	Target Neighborhood Hits	46	Shared Neighborhood Hits	5
SwissProt Accessions	P17427, Q921V0	Gene names	Ap2a2, Adtab
Domain Architecture
Description	AP-2 complex subunit alpha-2 (Adapter-related protein complex 2 alpha- 2 subunit) (Alpha-adaptin C) (Adaptor protein complex AP-2 alpha-2 subunit) (Clathrin assembly protein complex 2 alpha-C large chain) (100 kDa coated vesicle protein C) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit).

HIPK3_HUMAN
NC score	0.005467 (rank : 437)	θ value	3.0926 (rank : 162)
Query Neighborhood Hits	288	Target Neighborhood Hits	867	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H422, O14632, Q2PBG4, Q2PBG5, Q92632, Q9HAS2	Gene names	HIPK3, DYRK6, FIST3, PKY
Domain Architecture	No domain graphic available
Description	Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Homolog of protein kinase YAK1) (Fas-interacting serine/threonine-protein kinase) (FIST) (Androgen receptor-interacting nuclear protein kinase) (ANPK).

FOXE3_HUMAN
NC score	0.005221 (rank : 438)	θ value	4.03905 (rank : 185)
Query Neighborhood Hits	288	Target Neighborhood Hits	112	Shared Neighborhood Hits	8
SwissProt Accessions	Q13461, Q5SVY9, Q9NQV9	Gene names	FOXE3, FKHL12, FREAC8
Domain Architecture
Description	Forkhead box protein E3 (Forkhead-related protein FKHL12) (Forkhead- related transcription factor 8) (FREAC-8).

M3K12_MOUSE
NC score	0.004610 (rank : 439)	θ value	5.27518 (rank : 215)
Query Neighborhood Hits	288	Target Neighborhood Hits	957	Shared Neighborhood Hits	30
SwissProt Accessions	Q60700, P70286, Q3TLL7, Q8C4N7, Q8CBX3, Q8CDL6	Gene names	Map3k12, Zpk
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

HXC11_HUMAN
NC score	0.004201 (rank : 440)	θ value	8.99809 (rank : 264)
Query Neighborhood Hits	288	Target Neighborhood Hits	349	Shared Neighborhood Hits	10
SwissProt Accessions	O43248, Q96DH2	Gene names	HOXC11
Domain Architecture
Description	Homeobox protein Hox-C11.

ZN219_HUMAN
NC score	0.002758 (rank : 441)	θ value	6.88961 (rank : 252)
Query Neighborhood Hits	288	Target Neighborhood Hits	876	Shared Neighborhood Hits	31
SwissProt Accessions	Q9P2Y4, Q8IYC1, Q9BW28	Gene names	ZNF219
Domain Architecture	No domain graphic available
Description	Zinc finger protein 219.

PIM2_MOUSE
NC score	0.002303 (rank : 442)	θ value	6.88961 (rank : 240)
Query Neighborhood Hits	288	Target Neighborhood Hits	809	Shared Neighborhood Hits	15
SwissProt Accessions	Q62070, Q62071, Q62072	Gene names	Pim2, Pim-2
Domain Architecture
Description	Serine/threonine-protein kinase Pim-2 (EC 2.7.11.1).