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Network neighborhood for query Sequence : TCGAP_HUMAN

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TCGAP_HUMAN
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TCGAP_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	872	Target Neighborhood Hits	872	Shared Neighborhood Hits	872
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TCGAP_MOUSE
θ value	0 (rank : 2)	NC score	0.875877 (rank : 2)
Query Neighborhood Hits	872	Target Neighborhood Hits	409	Shared Neighborhood Hits	319
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

CHIN_HUMAN
θ value	5.22648e-32 (rank : 3)	NC score	0.659995 (rank : 16)
Query Neighborhood Hits	872	Target Neighborhood Hits	227	Shared Neighborhood Hits	84
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIN_MOUSE
θ value	1.52067e-31 (rank : 4)	NC score	0.660885 (rank : 15)
Query Neighborhood Hits	872	Target Neighborhood Hits	229	Shared Neighborhood Hits	88
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIO_MOUSE
θ value	9.8567e-31 (rank : 5)	NC score	0.675935 (rank : 10)
Query Neighborhood Hits	872	Target Neighborhood Hits	130	Shared Neighborhood Hits	72
SwissProt Accessions	Q80XD1, Q9D9W2, Q9ER57	Gene names	Chn2, Arhgap3, Bch
Domain Architecture	No domain graphic available
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

CHIO_HUMAN
θ value	3.74554e-30 (rank : 6)	NC score	0.658757 (rank : 18)
Query Neighborhood Hits	872	Target Neighborhood Hits	220	Shared Neighborhood Hits	84
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

RHG12_MOUSE
θ value	7.80994e-28 (rank : 7)	NC score	0.692460 (rank : 6)
Query Neighborhood Hits	872	Target Neighborhood Hits	204	Shared Neighborhood Hits	85
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RHG12_HUMAN
θ value	5.06226e-27 (rank : 8)	NC score	0.692146 (rank : 7)
Query Neighborhood Hits	872	Target Neighborhood Hits	190	Shared Neighborhood Hits	83
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RHG09_HUMAN
θ value	9.54697e-26 (rank : 9)	NC score	0.723695 (rank : 3)
Query Neighborhood Hits	872	Target Neighborhood Hits	186	Shared Neighborhood Hits	103
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

ABR_HUMAN
θ value	6.84181e-24 (rank : 10)	NC score	0.647366 (rank : 21)
Query Neighborhood Hits	872	Target Neighborhood Hits	166	Shared Neighborhood Hits	94
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

3BP1_HUMAN
θ value	4.9032e-22 (rank : 11)	NC score	0.703298 (rank : 4)
Query Neighborhood Hits	872	Target Neighborhood Hits	376	Shared Neighborhood Hits	179
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

3BP1_MOUSE
θ value	1.86321e-21 (rank : 12)	NC score	0.700524 (rank : 5)
Query Neighborhood Hits	872	Target Neighborhood Hits	238	Shared Neighborhood Hits	116
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

BCR_HUMAN
θ value	5.42112e-21 (rank : 13)	NC score	0.640773 (rank : 24)
Query Neighborhood Hits	872	Target Neighborhood Hits	204	Shared Neighborhood Hits	104
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

RHG04_HUMAN
θ value	9.24701e-21 (rank : 14)	NC score	0.672142 (rank : 11)
Query Neighborhood Hits	872	Target Neighborhood Hits	307	Shared Neighborhood Hits	175
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

RHG26_HUMAN
θ value	4.58923e-20 (rank : 15)	NC score	0.669469 (rank : 12)
Query Neighborhood Hits	872	Target Neighborhood Hits	281	Shared Neighborhood Hits	150
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

GMIP_MOUSE
θ value	5.99374e-20 (rank : 16)	NC score	0.684396 (rank : 8)
Query Neighborhood Hits	872	Target Neighborhood Hits	202	Shared Neighborhood Hits	81
SwissProt Accessions	Q6PGG2, Q6P9S3	Gene names	Gmip
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

OPHN1_MOUSE
θ value	3.88503e-19 (rank : 17)	NC score	0.644684 (rank : 23)
Query Neighborhood Hits	872	Target Neighborhood Hits	174	Shared Neighborhood Hits	70
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

OPHN1_HUMAN
θ value	1.13037e-18 (rank : 18)	NC score	0.646828 (rank : 22)
Query Neighborhood Hits	872	Target Neighborhood Hits	161	Shared Neighborhood Hits	81
SwissProt Accessions	O60890, Q5JQ81, Q8WX47	Gene names	OPHN1
Domain Architecture
Description	Oligophrenin 1.

MYO9B_HUMAN
θ value	1.92812e-18 (rank : 19)	NC score	0.375159 (rank : 57)
Query Neighborhood Hits	872	Target Neighborhood Hits	641	Shared Neighborhood Hits	181
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

RBP1_MOUSE
θ value	3.28887e-18 (rank : 20)	NC score	0.604919 (rank : 37)
Query Neighborhood Hits	872	Target Neighborhood Hits	493	Shared Neighborhood Hits	81
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

GMIP_HUMAN
θ value	4.29542e-18 (rank : 21)	NC score	0.677516 (rank : 9)
Query Neighborhood Hits	872	Target Neighborhood Hits	225	Shared Neighborhood Hits	91
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

MYO9B_MOUSE
θ value	5.60996e-18 (rank : 22)	NC score	0.364728 (rank : 59)
Query Neighborhood Hits	872	Target Neighborhood Hits	311	Shared Neighborhood Hits	93
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

RHG25_MOUSE
θ value	5.60996e-18 (rank : 23)	NC score	0.610203 (rank : 36)
Query Neighborhood Hits	872	Target Neighborhood Hits	492	Shared Neighborhood Hits	102
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

CEND3_HUMAN
θ value	2.7842e-17 (rank : 24)	NC score	0.514406 (rank : 51)
Query Neighborhood Hits	872	Target Neighborhood Hits	275	Shared Neighborhood Hits	107
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

RBP1_HUMAN
θ value	2.7842e-17 (rank : 25)	NC score	0.587201 (rank : 38)
Query Neighborhood Hits	872	Target Neighborhood Hits	521	Shared Neighborhood Hits	79
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

RGAP1_HUMAN
θ value	6.20254e-17 (rank : 26)	NC score	0.669249 (rank : 13)
Query Neighborhood Hits	872	Target Neighborhood Hits	189	Shared Neighborhood Hits	68
SwissProt Accessions	Q9H0H5, Q6PJ26, Q9NWN2, Q9P250, Q9P2W2	Gene names	RACGAP1, KIAA1478, MGCRACGAP
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

GRLF1_HUMAN
θ value	1.80466e-16 (rank : 27)	NC score	0.648517 (rank : 20)
Query Neighborhood Hits	872	Target Neighborhood Hits	167	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

RGAP1_MOUSE
θ value	2.35696e-16 (rank : 28)	NC score	0.668923 (rank : 14)
Query Neighborhood Hits	872	Target Neighborhood Hits	185	Shared Neighborhood Hits	67
SwissProt Accessions	Q9WVM1, Q3THR5, Q3TI41, Q3TM81	Gene names	Racgap1, Mgcracgap
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

SRGP1_HUMAN
θ value	4.02038e-16 (rank : 29)	NC score	0.621832 (rank : 33)
Query Neighborhood Hits	872	Target Neighborhood Hits	390	Shared Neighborhood Hits	165
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

RHG05_MOUSE
θ value	8.95645e-16 (rank : 30)	NC score	0.622388 (rank : 32)
Query Neighborhood Hits	872	Target Neighborhood Hits	165	Shared Neighborhood Hits	71
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

CEND3_MOUSE
θ value	7.58209e-15 (rank : 31)	NC score	0.513004 (rank : 52)
Query Neighborhood Hits	872	Target Neighborhood Hits	228	Shared Neighborhood Hits	85
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

FNBP2_HUMAN
θ value	7.58209e-15 (rank : 32)	NC score	0.619178 (rank : 34)
Query Neighborhood Hits	872	Target Neighborhood Hits	432	Shared Neighborhood Hits	177
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

RHG06_HUMAN
θ value	9.90251e-15 (rank : 33)	NC score	0.659217 (rank : 17)
Query Neighborhood Hits	872	Target Neighborhood Hits	114	Shared Neighborhood Hits	77
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RHG01_HUMAN
θ value	1.29331e-14 (rank : 34)	NC score	0.638009 (rank : 25)
Query Neighborhood Hits	872	Target Neighborhood Hits	75	Shared Neighborhood Hits	62
SwissProt Accessions	Q07960	Gene names	ARHGAP1, CDC42GAP, RHOGAP1
Domain Architecture
Description	Rho-GTPase-activating protein 1 (GTPase-activating protein rhoOGAP) (Rho-related small GTPase protein activator) (CDC42 GTPase-activating protein) (p50-RhoGAP).

RHG06_MOUSE
θ value	1.68911e-14 (rank : 35)	NC score	0.655044 (rank : 19)
Query Neighborhood Hits	872	Target Neighborhood Hits	105	Shared Neighborhood Hits	66
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RHG25_HUMAN
θ value	1.68911e-14 (rank : 36)	NC score	0.584316 (rank : 39)
Query Neighborhood Hits	872	Target Neighborhood Hits	550	Shared Neighborhood Hits	94
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RHG05_HUMAN
θ value	4.91457e-14 (rank : 37)	NC score	0.612141 (rank : 35)
Query Neighborhood Hits	872	Target Neighborhood Hits	158	Shared Neighborhood Hits	69
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

RHG08_HUMAN
θ value	6.41864e-14 (rank : 38)	NC score	0.624175 (rank : 31)
Query Neighborhood Hits	872	Target Neighborhood Hits	88	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NSG0, O75983, O95695, Q96RW1, Q96RW2, Q9HA49, Q9HC46, Q9NVX8, Q9NXL1, Q9UH20	Gene names	ARHGAP8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

CEND2_HUMAN
θ value	1.42992e-13 (rank : 39)	NC score	0.533023 (rank : 45)
Query Neighborhood Hits	872	Target Neighborhood Hits	166	Shared Neighborhood Hits	71
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

SRGP2_HUMAN
θ value	1.86753e-13 (rank : 40)	NC score	0.631064 (rank : 26)
Query Neighborhood Hits	872	Target Neighborhood Hits	331	Shared Neighborhood Hits	167
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

RHG07_MOUSE
θ value	4.16044e-13 (rank : 41)	NC score	0.565687 (rank : 40)
Query Neighborhood Hits	872	Target Neighborhood Hits	103	Shared Neighborhood Hits	63
SwissProt Accessions	Q9R0Z9, Q8R541	Gene names	Dlc1, Arhgap7, Stard12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein homolog) (Dlc-1) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

CE005_HUMAN
θ value	5.43371e-13 (rank : 42)	NC score	0.532303 (rank : 46)
Query Neighborhood Hits	872	Target Neighborhood Hits	213	Shared Neighborhood Hits	66
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

SRGP2_MOUSE
θ value	9.26847e-13 (rank : 43)	NC score	0.625525 (rank : 28)
Query Neighborhood Hits	872	Target Neighborhood Hits	324	Shared Neighborhood Hits	168
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

CE005_MOUSE
θ value	1.58096e-12 (rank : 44)	NC score	0.528494 (rank : 48)
Query Neighborhood Hits	872	Target Neighborhood Hits	238	Shared Neighborhood Hits	65
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

RHG08_MOUSE
θ value	1.58096e-12 (rank : 45)	NC score	0.624177 (rank : 30)
Query Neighborhood Hits	872	Target Neighborhood Hits	73	Shared Neighborhood Hits	62
SwissProt Accessions	Q9CXP4, Q99JY7	Gene names	Arhgap8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RHG07_HUMAN
θ value	3.52202e-12 (rank : 46)	NC score	0.559751 (rank : 41)
Query Neighborhood Hits	872	Target Neighborhood Hits	108	Shared Neighborhood Hits	63
SwissProt Accessions	Q96QB1, O14868, O43199, Q9C0E0	Gene names	DLC1, ARHGAP7, KIAA1723, STARD12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein) (Dlc-1) (HP protein) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

RHG18_HUMAN
θ value	1.133e-10 (rank : 47)	NC score	0.630850 (rank : 27)
Query Neighborhood Hits	872	Target Neighborhood Hits	90	Shared Neighborhood Hits	63
SwissProt Accessions	Q8N392, Q58EZ3, Q6P679, Q6PJD7, Q96S64	Gene names	ARHGAP18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18 (MacGAP).

STA13_HUMAN
θ value	1.133e-10 (rank : 48)	NC score	0.524386 (rank : 49)
Query Neighborhood Hits	872	Target Neighborhood Hits	89	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y3M8, Q5HYH1, Q5TAE3, Q6UN61, Q86TP6, Q86WQ3, Q86XT1	Gene names	STARD13, DLC2, GT650
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13) (46H23.2) (Deleted in liver cancer protein 2) (Rho GTPase-activating protein).

MUC1_HUMAN
θ value	1.9326e-10 (rank : 49)	NC score	0.303480 (rank : 62)
Query Neighborhood Hits	872	Target Neighborhood Hits	975	Shared Neighborhood Hits	389
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

STAR8_MOUSE
θ value	1.9326e-10 (rank : 50)	NC score	0.530580 (rank : 47)
Query Neighborhood Hits	872	Target Neighborhood Hits	101	Shared Neighborhood Hits	62
SwissProt Accessions	Q8K031, Q3UZC7, Q6A0A8, Q6P5E0, Q8R3X8	Gene names	Stard8, Kiaa0189
Domain Architecture	No domain graphic available
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

RHG18_MOUSE
θ value	2.52405e-10 (rank : 51)	NC score	0.624974 (rank : 29)
Query Neighborhood Hits	872	Target Neighborhood Hits	110	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K0Q5, Q8BP03, Q8R196	Gene names	Arhgap18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18.

STAR8_HUMAN
θ value	4.30538e-10 (rank : 52)	NC score	0.533570 (rank : 44)
Query Neighborhood Hits	872	Target Neighborhood Hits	216	Shared Neighborhood Hits	103
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

STA13_MOUSE
θ value	5.62301e-10 (rank : 53)	NC score	0.515776 (rank : 50)
Query Neighborhood Hits	872	Target Neighborhood Hits	89	Shared Neighborhood Hits	59
SwissProt Accessions	Q923Q2, Q8K369	Gene names	Stard13
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13).

CEND1_MOUSE
θ value	1.63604e-09 (rank : 54)	NC score	0.455514 (rank : 55)
Query Neighborhood Hits	872	Target Neighborhood Hits	260	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

K1688_MOUSE
θ value	2.13673e-09 (rank : 55)	NC score	0.497836 (rank : 54)
Query Neighborhood Hits	872	Target Neighborhood Hits	188	Shared Neighborhood Hits	103
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

CEND1_HUMAN
θ value	2.79066e-09 (rank : 56)	NC score	0.439657 (rank : 56)
Query Neighborhood Hits	872	Target Neighborhood Hits	284	Shared Neighborhood Hits	73
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

K1688_HUMAN
θ value	3.64472e-09 (rank : 57)	NC score	0.502977 (rank : 53)
Query Neighborhood Hits	872	Target Neighborhood Hits	217	Shared Neighborhood Hits	120
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

TAF4_HUMAN
θ value	4.76016e-09 (rank : 58)	NC score	0.176831 (rank : 138)
Query Neighborhood Hits	872	Target Neighborhood Hits	687	Shared Neighborhood Hits	183
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

P85A_HUMAN
θ value	3.08544e-08 (rank : 59)	NC score	0.368231 (rank : 58)
Query Neighborhood Hits	872	Target Neighborhood Hits	479	Shared Neighborhood Hits	123
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

CSTFT_MOUSE
θ value	1.17247e-07 (rank : 60)	NC score	0.073215 (rank : 519)
Query Neighborhood Hits	872	Target Neighborhood Hits	356	Shared Neighborhood Hits	91
SwissProt Accessions	Q8C7E9, Q6A016, Q8BHH7, Q8C3W7, Q8R2Y1, Q9EPU3	Gene names	Cstf2t, Kiaa0689
Domain Architecture	No domain graphic available
Description	Cleavage stimulation factor 64 kDa subunit, tau variant (CSTF 64 kDa subunit, tau variant) (CF-1 64 kDa subunit, tau variant) (TauCstF-64).

P85A_MOUSE
θ value	1.17247e-07 (rank : 61)	NC score	0.363922 (rank : 60)
Query Neighborhood Hits	872	Target Neighborhood Hits	435	Shared Neighborhood Hits	124
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

TAGAP_HUMAN
θ value	1.17247e-07 (rank : 62)	NC score	0.557328 (rank : 42)
Query Neighborhood Hits	872	Target Neighborhood Hits	82	Shared Neighborhood Hits	60
SwissProt Accessions	Q8N103, Q2NKM8, Q8NI40, Q96KZ2, Q96QA2	Gene names	TAGAP, TAGAP1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

ITSN1_MOUSE
θ value	5.81887e-07 (rank : 63)	NC score	0.181495 (rank : 133)
Query Neighborhood Hits	872	Target Neighborhood Hits	1669	Shared Neighborhood Hits	249
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

GRAP_HUMAN
θ value	7.59969e-07 (rank : 64)	NC score	0.220988 (rank : 84)
Query Neighborhood Hits	872	Target Neighborhood Hits	307	Shared Neighborhood Hits	143
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

CSKI2_HUMAN
θ value	9.92553e-07 (rank : 65)	NC score	0.084548 (rank : 436)
Query Neighborhood Hits	872	Target Neighborhood Hits	747	Shared Neighborhood Hits	182
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CPSF6_HUMAN
θ value	1.69304e-06 (rank : 66)	NC score	0.168562 (rank : 152)
Query Neighborhood Hits	872	Target Neighborhood Hits	359	Shared Neighborhood Hits	140
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

ITSN1_HUMAN
θ value	2.21117e-06 (rank : 67)	NC score	0.186031 (rank : 125)
Query Neighborhood Hits	872	Target Neighborhood Hits	1757	Shared Neighborhood Hits	285
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

TAB3_MOUSE
θ value	2.21117e-06 (rank : 68)	NC score	0.132210 (rank : 236)
Query Neighborhood Hits	872	Target Neighborhood Hits	273	Shared Neighborhood Hits	108
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

CPSF6_MOUSE
θ value	2.88788e-06 (rank : 69)	NC score	0.168406 (rank : 154)
Query Neighborhood Hits	872	Target Neighborhood Hits	356	Shared Neighborhood Hits	141
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

GRAP_MOUSE
θ value	2.88788e-06 (rank : 70)	NC score	0.217296 (rank : 88)
Query Neighborhood Hits	872	Target Neighborhood Hits	309	Shared Neighborhood Hits	141
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

SC24D_HUMAN
θ value	2.88788e-06 (rank : 71)	NC score	0.111543 (rank : 296)
Query Neighborhood Hits	872	Target Neighborhood Hits	173	Shared Neighborhood Hits	67
SwissProt Accessions	O94855	Gene names	SEC24D, KIAA0755
Domain Architecture
Description	Protein transport protein Sec24D (SEC24-related protein D).

TAGAP_MOUSE
θ value	4.92598e-06 (rank : 72)	NC score	0.557299 (rank : 43)
Query Neighborhood Hits	872	Target Neighborhood Hits	83	Shared Neighborhood Hits	61
SwissProt Accessions	Q8K2L9, Q920D6	Gene names	Tagap, Tagap1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

ENAH_MOUSE
θ value	6.43352e-06 (rank : 73)	NC score	0.122966 (rank : 256)
Query Neighborhood Hits	872	Target Neighborhood Hits	919	Shared Neighborhood Hits	198
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

CCD1A_HUMAN
θ value	8.40245e-06 (rank : 74)	NC score	0.082430 (rank : 456)
Query Neighborhood Hits	872	Target Neighborhood Hits	123	Shared Neighborhood Hits	35
SwissProt Accessions	Q6P1N0, Q7Z435, Q86XV0, Q8NF89, Q9H603, Q9NXI1	Gene names	CC2D1A
Domain Architecture	No domain graphic available
Description	Coiled-coil and C2 domain-containing protein 1A (Five repressor element under dual repression-binding protein 1) (FRE under dual repression-binding protein 1) (Freud-1) (Putative NF-kappa-B- activating protein 023N).

KLF2_HUMAN
θ value	1.09739e-05 (rank : 75)	NC score	0.012549 (rank : 1033)
Query Neighborhood Hits	872	Target Neighborhood Hits	755	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Y5W3, Q9UJS5, Q9UKR6	Gene names	KLF2, LKLF
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 2 (Lung krueppel-like factor).

NMDE4_MOUSE
θ value	1.09739e-05 (rank : 76)	NC score	0.044746 (rank : 804)
Query Neighborhood Hits	872	Target Neighborhood Hits	158	Shared Neighborhood Hits	47
SwissProt Accessions	Q03391	Gene names	Grin2d
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D).

EP400_MOUSE
θ value	1.43324e-05 (rank : 77)	NC score	0.073981 (rank : 514)
Query Neighborhood Hits	872	Target Neighborhood Hits	592	Shared Neighborhood Hits	154
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

RERE_HUMAN
θ value	1.43324e-05 (rank : 78)	NC score	0.135572 (rank : 225)
Query Neighborhood Hits	872	Target Neighborhood Hits	779	Shared Neighborhood Hits	214
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

SF3A2_MOUSE
θ value	1.43324e-05 (rank : 79)	NC score	0.154813 (rank : 184)
Query Neighborhood Hits	872	Target Neighborhood Hits	247	Shared Neighborhood Hits	97
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

PRP2_MOUSE
θ value	1.87187e-05 (rank : 80)	NC score	0.183809 (rank : 130)
Query Neighborhood Hits	872	Target Neighborhood Hits	347	Shared Neighborhood Hits	132
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

SF3B4_HUMAN
θ value	1.87187e-05 (rank : 81)	NC score	0.071926 (rank : 529)
Query Neighborhood Hits	872	Target Neighborhood Hits	445	Shared Neighborhood Hits	111
SwissProt Accessions	Q15427	Gene names	SF3B4, SAP49
Domain Architecture
Description	Splicing factor 3B subunit 4 (Spliceosome-associated protein 49) (SAP 49) (SF3b50) (Pre-mRNA-splicing factor SF3b 49 kDa subunit).

SF3A2_HUMAN
θ value	2.44474e-05 (rank : 82)	NC score	0.156948 (rank : 179)
Query Neighborhood Hits	872	Target Neighborhood Hits	263	Shared Neighborhood Hits	105
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

CN032_MOUSE
θ value	4.1701e-05 (rank : 83)	NC score	0.174672 (rank : 142)
Query Neighborhood Hits	872	Target Neighborhood Hits	233	Shared Neighborhood Hits	110
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

SMRC2_MOUSE
θ value	4.1701e-05 (rank : 84)	NC score	0.105881 (rank : 317)
Query Neighborhood Hits	872	Target Neighborhood Hits	487	Shared Neighborhood Hits	101
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

HCN4_HUMAN
θ value	5.44631e-05 (rank : 85)	NC score	0.059169 (rank : 654)
Query Neighborhood Hits	872	Target Neighborhood Hits	303	Shared Neighborhood Hits	101
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

GSCR1_HUMAN
θ value	7.1131e-05 (rank : 86)	NC score	0.160385 (rank : 171)
Query Neighborhood Hits	872	Target Neighborhood Hits	674	Shared Neighborhood Hits	232
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

I5P2_HUMAN
θ value	9.29e-05 (rank : 87)	NC score	0.307655 (rank : 61)
Query Neighborhood Hits	872	Target Neighborhood Hits	86	Shared Neighborhood Hits	59
SwissProt Accessions	P32019, Q5VSG9, Q5VSH0, Q5VSH1, Q658Q5, Q6P6D4, Q6PD53, Q86YE1	Gene names	INPP5B
Domain Architecture	No domain graphic available
Description	Type II inositol-1,4,5-trisphosphate 5-phosphatase precursor (EC 3.1.3.36) (Phosphoinositide 5-phosphatase) (5PTase) (75 kDa inositol polyphosphate-5-phosphatase).

OCRL_HUMAN
θ value	9.29e-05 (rank : 88)	NC score	0.300028 (rank : 63)
Query Neighborhood Hits	872	Target Neighborhood Hits	77	Shared Neighborhood Hits	58
SwissProt Accessions	Q01968, O60800, Q15684, Q15774, Q5JQF1, Q5JQF2, Q9UJG5, Q9UMA5	Gene names	OCRL, INPP5F, OCRL1
Domain Architecture
Description	Inositol polyphosphate 5-phosphatase OCRL-1 (EC 3.1.3.36) (Lowe oculocerebrorenal syndrome protein).

TAB3_HUMAN
θ value	0.000121331 (rank : 89)	NC score	0.092385 (rank : 380)
Query Neighborhood Hits	872	Target Neighborhood Hits	168	Shared Neighborhood Hits	45
SwissProt Accessions	Q8N5C8, Q6VQR0	Gene names	MAP3K7IP3, TAB3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3) (NF-kappa-B-activating protein 1).

BAT2_HUMAN
θ value	0.000158464 (rank : 90)	NC score	0.194958 (rank : 114)
Query Neighborhood Hits	872	Target Neighborhood Hits	931	Shared Neighborhood Hits	307
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CENG1_MOUSE
θ value	0.000158464 (rank : 91)	NC score	0.083564 (rank : 447)
Query Neighborhood Hits	872	Target Neighborhood Hits	531	Shared Neighborhood Hits	78
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

FOG1_HUMAN
θ value	0.000158464 (rank : 92)	NC score	0.033003 (rank : 872)
Query Neighborhood Hits	872	Target Neighborhood Hits	981	Shared Neighborhood Hits	146
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

GGN_MOUSE
θ value	0.000158464 (rank : 93)	NC score	0.133310 (rank : 232)
Query Neighborhood Hits	872	Target Neighborhood Hits	311	Shared Neighborhood Hits	112
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

MBD6_HUMAN
θ value	0.000158464 (rank : 94)	NC score	0.151504 (rank : 190)
Query Neighborhood Hits	872	Target Neighborhood Hits	349	Shared Neighborhood Hits	125
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

WIRE_HUMAN
θ value	0.000158464 (rank : 95)	NC score	0.153096 (rank : 188)
Query Neighborhood Hits	872	Target Neighborhood Hits	329	Shared Neighborhood Hits	116
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

BAT2_MOUSE
θ value	0.00020696 (rank : 96)	NC score	0.190965 (rank : 121)
Query Neighborhood Hits	872	Target Neighborhood Hits	947	Shared Neighborhood Hits	317
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

HCN4_MOUSE
θ value	0.00020696 (rank : 97)	NC score	0.056776 (rank : 682)
Query Neighborhood Hits	872	Target Neighborhood Hits	284	Shared Neighborhood Hits	87
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

M3K9_HUMAN
θ value	0.00020696 (rank : 98)	NC score	0.047217 (rank : 795)
Query Neighborhood Hits	872	Target Neighborhood Hits	1123	Shared Neighborhood Hits	176
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

RSMN_HUMAN
θ value	0.00020696 (rank : 99)	NC score	0.118791 (rank : 267)
Query Neighborhood Hits	872	Target Neighborhood Hits	110	Shared Neighborhood Hits	45
SwissProt Accessions	P63162, P14648, P17135	Gene names	SNRPN, HCERN3, SMN
Domain Architecture	No domain graphic available
Description	Small nuclear ribonucleoprotein-associated protein N (snRNP-N) (Sm protein N) (Sm-N) (SmN) (Sm-D) (Tissue-specific-splicing protein).

RSMN_MOUSE
θ value	0.00020696 (rank : 100)	NC score	0.118791 (rank : 268)
Query Neighborhood Hits	872	Target Neighborhood Hits	110	Shared Neighborhood Hits	45
SwissProt Accessions	P63163, P14648, P17135	Gene names	Snrpn, Smn
Domain Architecture	No domain graphic available
Description	Small nuclear ribonucleoprotein-associated protein N (snRNP-N) (Sm protein N) (Sm-N) (SmN) (Sm-D) (Tissue-specific-splicing protein).

WASIP_MOUSE
θ value	0.00020696 (rank : 101)	NC score	0.167145 (rank : 156)
Query Neighborhood Hits	872	Target Neighborhood Hits	392	Shared Neighborhood Hits	163
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

ARHG4_HUMAN
θ value	0.000270298 (rank : 102)	NC score	0.188331 (rank : 122)
Query Neighborhood Hits	872	Target Neighborhood Hits	242	Shared Neighborhood Hits	125
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

WASF2_HUMAN
θ value	0.000270298 (rank : 103)	NC score	0.134143 (rank : 231)
Query Neighborhood Hits	872	Target Neighborhood Hits	280	Shared Neighborhood Hits	118
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

WBS14_HUMAN
θ value	0.000270298 (rank : 104)	NC score	0.079468 (rank : 474)
Query Neighborhood Hits	872	Target Neighborhood Hits	273	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

WIRE_MOUSE
θ value	0.000270298 (rank : 105)	NC score	0.154570 (rank : 186)
Query Neighborhood Hits	872	Target Neighborhood Hits	310	Shared Neighborhood Hits	120
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

ANXA7_MOUSE
θ value	0.00035302 (rank : 106)	NC score	0.049958 (rank : 781)
Query Neighborhood Hits	872	Target Neighborhood Hits	142	Shared Neighborhood Hits	54
SwissProt Accessions	Q07076	Gene names	Anxa7, Anx7
Domain Architecture
Description	Annexin A7 (Annexin VII) (Synexin).

BCAR1_MOUSE
θ value	0.00035302 (rank : 107)	NC score	0.225368 (rank : 81)
Query Neighborhood Hits	872	Target Neighborhood Hits	438	Shared Neighborhood Hits	251
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

NFH_MOUSE
θ value	0.00035302 (rank : 108)	NC score	0.129848 (rank : 241)
Query Neighborhood Hits	872	Target Neighborhood Hits	2247	Shared Neighborhood Hits	413
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

SC24C_HUMAN
θ value	0.00035302 (rank : 109)	NC score	0.236196 (rank : 78)
Query Neighborhood Hits	872	Target Neighborhood Hits	662	Shared Neighborhood Hits	330
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

ARI1B_HUMAN
θ value	0.000461057 (rank : 110)	NC score	0.138073 (rank : 219)
Query Neighborhood Hits	872	Target Neighborhood Hits	567	Shared Neighborhood Hits	215
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

CN032_HUMAN
θ value	0.000461057 (rank : 111)	NC score	0.169479 (rank : 151)
Query Neighborhood Hits	872	Target Neighborhood Hits	267	Shared Neighborhood Hits	117
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

SMRC2_HUMAN
θ value	0.000461057 (rank : 112)	NC score	0.103089 (rank : 326)
Query Neighborhood Hits	872	Target Neighborhood Hits	499	Shared Neighborhood Hits	103
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

SYN1_MOUSE
θ value	0.000461057 (rank : 113)	NC score	0.097792 (rank : 344)
Query Neighborhood Hits	872	Target Neighborhood Hits	363	Shared Neighborhood Hits	125
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

WASIP_HUMAN
θ value	0.000461057 (rank : 114)	NC score	0.165004 (rank : 161)
Query Neighborhood Hits	872	Target Neighborhood Hits	458	Shared Neighborhood Hits	161
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

EPN1_MOUSE
θ value	0.000602161 (rank : 115)	NC score	0.092443 (rank : 378)
Query Neighborhood Hits	872	Target Neighborhood Hits	240	Shared Neighborhood Hits	104
SwissProt Accessions	Q80VP1, O70446	Gene names	Epn1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (Intersectin-EH-binding protein 1) (Ibp1).

PCLO_MOUSE
θ value	0.000602161 (rank : 116)	NC score	0.191947 (rank : 119)
Query Neighborhood Hits	872	Target Neighborhood Hits	2275	Shared Neighborhood Hits	510
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

WBP11_MOUSE
θ value	0.000602161 (rank : 117)	NC score	0.140778 (rank : 209)
Query Neighborhood Hits	872	Target Neighborhood Hits	362	Shared Neighborhood Hits	131
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

DIAP1_MOUSE
θ value	0.000786445 (rank : 118)	NC score	0.083208 (rank : 450)
Query Neighborhood Hits	872	Target Neighborhood Hits	839	Shared Neighborhood Hits	128
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

FREA_HUMAN
θ value	0.000786445 (rank : 119)	NC score	0.039223 (rank : 838)
Query Neighborhood Hits	872	Target Neighborhood Hits	205	Shared Neighborhood Hits	84
SwissProt Accessions	O43638, Q96D28	Gene names	FKHL18, FREAC10
Domain Architecture	No domain graphic available
Description	Forkhead-related transcription factor 10 (FREAC-10) (Forkhead-like 18 protein).

RPB1_HUMAN
θ value	0.000786445 (rank : 120)	NC score	0.086927 (rank : 416)
Query Neighborhood Hits	872	Target Neighborhood Hits	362	Shared Neighborhood Hits	89
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_MOUSE
θ value	0.000786445 (rank : 121)	NC score	0.087429 (rank : 413)
Query Neighborhood Hits	872	Target Neighborhood Hits	363	Shared Neighborhood Hits	89
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

SRC8_MOUSE
θ value	0.000786445 (rank : 122)	NC score	0.219473 (rank : 85)
Query Neighborhood Hits	872	Target Neighborhood Hits	292	Shared Neighborhood Hits	128
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

CD2AP_HUMAN
θ value	0.00102713 (rank : 123)	NC score	0.240759 (rank : 72)
Query Neighborhood Hits	872	Target Neighborhood Hits	315	Shared Neighborhood Hits	136
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

CD2AP_MOUSE
θ value	0.00102713 (rank : 124)	NC score	0.238132 (rank : 74)
Query Neighborhood Hits	872	Target Neighborhood Hits	336	Shared Neighborhood Hits	147
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

CENG1_HUMAN
θ value	0.00102713 (rank : 125)	NC score	0.077884 (rank : 486)
Query Neighborhood Hits	872	Target Neighborhood Hits	544	Shared Neighborhood Hits	76
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

FMNL_MOUSE
θ value	0.00102713 (rank : 126)	NC score	0.106368 (rank : 316)
Query Neighborhood Hits	872	Target Neighborhood Hits	428	Shared Neighborhood Hits	108
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

RSMB_HUMAN
θ value	0.00102713 (rank : 127)	NC score	0.118452 (rank : 270)
Query Neighborhood Hits	872	Target Neighborhood Hits	117	Shared Neighborhood Hits	51
SwissProt Accessions	P14678, Q15490, Q9UIS5	Gene names	SNRPB, COD, SNRPB1
Domain Architecture
Description	Small nuclear ribonucleoprotein-associated proteins B and B' (snRNP-B) (Sm protein B/B') (Sm-B/Sm-B') (SmB/SmB').

SBK1_HUMAN
θ value	0.00102713 (rank : 128)	NC score	0.003672 (rank : 1102)
Query Neighborhood Hits	872	Target Neighborhood Hits	828	Shared Neighborhood Hits	40
SwissProt Accessions	Q52WX2	Gene names	SBK1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SBK1 (EC 2.7.11.1) (SH3-binding kinase 1).

STAC3_HUMAN
θ value	0.00102713 (rank : 129)	NC score	0.224705 (rank : 82)
Query Neighborhood Hits	872	Target Neighborhood Hits	228	Shared Neighborhood Hits	113
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC3_MOUSE
θ value	0.00102713 (rank : 130)	NC score	0.225484 (rank : 80)
Query Neighborhood Hits	872	Target Neighborhood Hits	232	Shared Neighborhood Hits	112
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

WASL_MOUSE
θ value	0.00102713 (rank : 131)	NC score	0.110777 (rank : 300)
Query Neighborhood Hits	872	Target Neighborhood Hits	339	Shared Neighborhood Hits	126
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

YLPM1_HUMAN
θ value	0.00102713 (rank : 132)	NC score	0.136369 (rank : 224)
Query Neighborhood Hits	872	Target Neighborhood Hits	670	Shared Neighborhood Hits	187
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

AB1IP_HUMAN
θ value	0.00134147 (rank : 133)	NC score	0.081252 (rank : 458)
Query Neighborhood Hits	872	Target Neighborhood Hits	213	Shared Neighborhood Hits	71
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

HCLS1_HUMAN
θ value	0.00134147 (rank : 134)	NC score	0.257307 (rank : 67)
Query Neighborhood Hits	872	Target Neighborhood Hits	358	Shared Neighborhood Hits	201
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

ITSN2_HUMAN
θ value	0.00134147 (rank : 135)	NC score	0.172305 (rank : 145)
Query Neighborhood Hits	872	Target Neighborhood Hits	1173	Shared Neighborhood Hits	178
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

WASF2_MOUSE
θ value	0.00134147 (rank : 136)	NC score	0.138171 (rank : 218)
Query Neighborhood Hits	872	Target Neighborhood Hits	315	Shared Neighborhood Hits	132
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

ITSN2_MOUSE
θ value	0.00175202 (rank : 137)	NC score	0.165527 (rank : 159)
Query Neighborhood Hits	872	Target Neighborhood Hits	1371	Shared Neighborhood Hits	187
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

OSTF1_MOUSE
θ value	0.00175202 (rank : 138)	NC score	0.164024 (rank : 165)
Query Neighborhood Hits	872	Target Neighborhood Hits	467	Shared Neighborhood Hits	134
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

PRP1_HUMAN
θ value	0.00175202 (rank : 139)	NC score	0.156219 (rank : 181)
Query Neighborhood Hits	872	Target Neighborhood Hits	385	Shared Neighborhood Hits	150
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

RXRB_HUMAN
θ value	0.00175202 (rank : 140)	NC score	0.028471 (rank : 905)
Query Neighborhood Hits	872	Target Neighborhood Hits	280	Shared Neighborhood Hits	83
SwissProt Accessions	P28702, P28703	Gene names	RXRB, NR2B2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta).

WASF4_HUMAN
θ value	0.00175202 (rank : 141)	NC score	0.130880 (rank : 239)
Query Neighborhood Hits	872	Target Neighborhood Hits	282	Shared Neighborhood Hits	121
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

ASPP1_HUMAN
θ value	0.00228821 (rank : 142)	NC score	0.139866 (rank : 215)
Query Neighborhood Hits	872	Target Neighborhood Hits	956	Shared Neighborhood Hits	198
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

CSTFT_HUMAN
θ value	0.00228821 (rank : 143)	NC score	0.052831 (rank : 744)
Query Neighborhood Hits	872	Target Neighborhood Hits	292	Shared Neighborhood Hits	56
SwissProt Accessions	Q9H0L4, O75174, Q53HK6, Q7LGE8, Q8N6T1	Gene names	CSTF2T, KIAA0689
Domain Architecture	No domain graphic available
Description	Cleavage stimulation factor 64 kDa subunit, tau variant (CSTF 64 kDa subunit, tau variant) (CF-1 64 kDa subunit, tau variant) (TauCstF-64).

MYO1E_HUMAN
θ value	0.00228821 (rank : 144)	NC score	0.119964 (rank : 262)
Query Neighborhood Hits	872	Target Neighborhood Hits	293	Shared Neighborhood Hits	137
SwissProt Accessions	Q12965, Q14778	Gene names	MYO1E, MYO1C
Domain Architecture
Description	Myosin Ie (Myosin Ic).

OSTF1_HUMAN
θ value	0.00228821 (rank : 145)	NC score	0.166190 (rank : 157)
Query Neighborhood Hits	872	Target Neighborhood Hits	466	Shared Neighborhood Hits	134
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

PRB3_HUMAN
θ value	0.00228821 (rank : 146)	NC score	0.131471 (rank : 237)
Query Neighborhood Hits	872	Target Neighborhood Hits	318	Shared Neighborhood Hits	117
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

STAM2_HUMAN
θ value	0.00228821 (rank : 147)	NC score	0.193445 (rank : 117)
Query Neighborhood Hits	872	Target Neighborhood Hits	288	Shared Neighborhood Hits	135
SwissProt Accessions	O75886, Q7LDQ0, Q9UF58	Gene names	STAM2
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2).

WNK2_HUMAN
θ value	0.00228821 (rank : 148)	NC score	0.032474 (rank : 880)
Query Neighborhood Hits	872	Target Neighborhood Hits	1407	Shared Neighborhood Hits	246
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

ABI1_MOUSE
θ value	0.00298849 (rank : 149)	NC score	0.200248 (rank : 105)
Query Neighborhood Hits	872	Target Neighborhood Hits	246	Shared Neighborhood Hits	144
SwissProt Accessions	Q8CBW3, Q60747, Q91ZM5, Q923I9, Q99KH4	Gene names	Abi1, Ssh3bp1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Ablphilin-1).

BCAR1_HUMAN
θ value	0.00298849 (rank : 150)	NC score	0.248133 (rank : 68)
Query Neighborhood Hits	872	Target Neighborhood Hits	554	Shared Neighborhood Hits	300
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

COEA1_MOUSE
θ value	0.00298849 (rank : 151)	NC score	0.054882 (rank : 711)
Query Neighborhood Hits	872	Target Neighborhood Hits	402	Shared Neighborhood Hits	95
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

HCLS1_MOUSE
θ value	0.00298849 (rank : 152)	NC score	0.243088 (rank : 71)
Query Neighborhood Hits	872	Target Neighborhood Hits	329	Shared Neighborhood Hits	170
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

NMDE4_HUMAN
θ value	0.00298849 (rank : 153)	NC score	0.039400 (rank : 836)
Query Neighborhood Hits	872	Target Neighborhood Hits	133	Shared Neighborhood Hits	38
SwissProt Accessions	O15399	Gene names	GRIN2D
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D) (EB11).

PCX3_MOUSE
θ value	0.00298849 (rank : 154)	NC score	0.060036 (rank : 642)
Query Neighborhood Hits	872	Target Neighborhood Hits	134	Shared Neighborhood Hits	49
SwissProt Accessions	Q8VI59	Gene names	Pcnxl3
Domain Architecture
Description	Pecanex-like protein 3.

SF01_HUMAN
θ value	0.00298849 (rank : 155)	NC score	0.106872 (rank : 313)
Query Neighborhood Hits	872	Target Neighborhood Hits	287	Shared Neighborhood Hits	106
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

STAM2_MOUSE
θ value	0.00298849 (rank : 156)	NC score	0.194096 (rank : 116)
Query Neighborhood Hits	872	Target Neighborhood Hits	285	Shared Neighborhood Hits	135
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

TENS1_HUMAN
θ value	0.00298849 (rank : 157)	NC score	0.076372 (rank : 499)
Query Neighborhood Hits	872	Target Neighborhood Hits	400	Shared Neighborhood Hits	119
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

WBP11_HUMAN
θ value	0.00298849 (rank : 158)	NC score	0.139302 (rank : 216)
Query Neighborhood Hits	872	Target Neighborhood Hits	354	Shared Neighborhood Hits	127
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

ASPP1_MOUSE
θ value	0.00390308 (rank : 159)	NC score	0.176042 (rank : 141)
Query Neighborhood Hits	872	Target Neighborhood Hits	1244	Shared Neighborhood Hits	312
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

CSKI1_HUMAN
θ value	0.00390308 (rank : 160)	NC score	0.091127 (rank : 385)
Query Neighborhood Hits	872	Target Neighborhood Hits	997	Shared Neighborhood Hits	288
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

FMNL_HUMAN
θ value	0.00390308 (rank : 161)	NC score	0.130187 (rank : 240)
Query Neighborhood Hits	872	Target Neighborhood Hits	529	Shared Neighborhood Hits	149
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

M3K11_HUMAN
θ value	0.00390308 (rank : 162)	NC score	0.048740 (rank : 787)
Query Neighborhood Hits	872	Target Neighborhood Hits	1136	Shared Neighborhood Hits	196
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

PCLO_HUMAN
θ value	0.00390308 (rank : 163)	NC score	0.155089 (rank : 183)
Query Neighborhood Hits	872	Target Neighborhood Hits	2046	Shared Neighborhood Hits	401
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PYGO2_HUMAN
θ value	0.00390308 (rank : 164)	NC score	0.105609 (rank : 318)
Query Neighborhood Hits	872	Target Neighborhood Hits	189	Shared Neighborhood Hits	98
SwissProt Accessions	Q9BRQ0, Q8WYZ4, Q96CY2	Gene names	PYGO2
Domain Architecture
Description	Pygopus homolog 2.

SHAN1_HUMAN
θ value	0.00390308 (rank : 165)	NC score	0.116086 (rank : 281)
Query Neighborhood Hits	872	Target Neighborhood Hits	1041	Shared Neighborhood Hits	269
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SMR3A_HUMAN
θ value	0.00390308 (rank : 166)	NC score	0.127890 (rank : 245)
Query Neighborhood Hits	872	Target Neighborhood Hits	93	Shared Neighborhood Hits	37
SwissProt Accessions	Q99954	Gene names	SMR3A, PBI, PROL5
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog A precursor (Proline-rich protein 5) (Proline-rich protein PBI).

ARHG9_HUMAN
θ value	0.00509761 (rank : 167)	NC score	0.187507 (rank : 124)
Query Neighborhood Hits	872	Target Neighborhood Hits	235	Shared Neighborhood Hits	129
SwissProt Accessions	O43307, Q5JSL6	Gene names	ARHGEF9, KIAA0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin) (PEM-2 homolog).

ARHG9_MOUSE
θ value	0.00509761 (rank : 168)	NC score	0.187706 (rank : 123)
Query Neighborhood Hits	872	Target Neighborhood Hits	234	Shared Neighborhood Hits	127
SwissProt Accessions	Q3UTH8, Q3TQ60, Q80U06, Q8CAF9	Gene names	Arhgef9, Kiaa0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin).

COEA1_HUMAN
θ value	0.00509761 (rank : 169)	NC score	0.060459 (rank : 637)
Query Neighborhood Hits	872	Target Neighborhood Hits	427	Shared Neighborhood Hits	103
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

FGD1_HUMAN
θ value	0.00509761 (rank : 170)	NC score	0.086431 (rank : 419)
Query Neighborhood Hits	872	Target Neighborhood Hits	367	Shared Neighborhood Hits	111
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

K1802_MOUSE
θ value	0.00509761 (rank : 171)	NC score	0.170377 (rank : 149)
Query Neighborhood Hits	872	Target Neighborhood Hits	1596	Shared Neighborhood Hits	374
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MYO1F_HUMAN
θ value	0.00509761 (rank : 172)	NC score	0.121543 (rank : 258)
Query Neighborhood Hits	872	Target Neighborhood Hits	275	Shared Neighborhood Hits	133
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

RAPH1_HUMAN
θ value	0.00509761 (rank : 173)	NC score	0.126214 (rank : 249)
Query Neighborhood Hits	872	Target Neighborhood Hits	593	Shared Neighborhood Hits	179
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

SF01_MOUSE
θ value	0.00509761 (rank : 174)	NC score	0.097295 (rank : 346)
Query Neighborhood Hits	872	Target Neighborhood Hits	240	Shared Neighborhood Hits	85
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

SRC8_HUMAN
θ value	0.00509761 (rank : 175)	NC score	0.213046 (rank : 92)
Query Neighborhood Hits	872	Target Neighborhood Hits	269	Shared Neighborhood Hits	118
SwissProt Accessions	Q14247	Gene names	CTTN, EMS1
Domain Architecture
Description	Src substrate cortactin (Amplaxin) (Oncogene EMS1).

TACC3_HUMAN
θ value	0.00509761 (rank : 176)	NC score	0.075865 (rank : 505)
Query Neighborhood Hits	872	Target Neighborhood Hits	779	Shared Neighborhood Hits	118
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

WDR33_HUMAN
θ value	0.00509761 (rank : 177)	NC score	0.057035 (rank : 680)
Query Neighborhood Hits	872	Target Neighborhood Hits	638	Shared Neighborhood Hits	142
SwissProt Accessions	Q9C0J8	Gene names	WDR33, WDC146
Domain Architecture
Description	WD repeat protein 33 (WD repeat protein WDC146).

ATN1_HUMAN
θ value	0.00665767 (rank : 178)	NC score	0.144427 (rank : 203)
Query Neighborhood Hits	872	Target Neighborhood Hits	676	Shared Neighborhood Hits	194
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

DVL2_HUMAN
θ value	0.00665767 (rank : 179)	NC score	0.045349 (rank : 802)
Query Neighborhood Hits	872	Target Neighborhood Hits	223	Shared Neighborhood Hits	43
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

FMN2_HUMAN
θ value	0.00665767 (rank : 180)	NC score	0.116881 (rank : 276)
Query Neighborhood Hits	872	Target Neighborhood Hits	484	Shared Neighborhood Hits	139
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

IASPP_HUMAN
θ value	0.00665767 (rank : 181)	NC score	0.168546 (rank : 153)
Query Neighborhood Hits	872	Target Neighborhood Hits	688	Shared Neighborhood Hits	216
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

MLL4_HUMAN
θ value	0.00665767 (rank : 182)	NC score	0.087432 (rank : 412)
Query Neighborhood Hits	872	Target Neighborhood Hits	722	Shared Neighborhood Hits	188
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

NOTC2_MOUSE
θ value	0.00665767 (rank : 183)	NC score	0.036188 (rank : 858)
Query Neighborhood Hits	872	Target Neighborhood Hits	1069	Shared Neighborhood Hits	154
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

RP1L1_HUMAN
θ value	0.00665767 (rank : 184)	NC score	0.082986 (rank : 451)
Query Neighborhood Hits	872	Target Neighborhood Hits	1072	Shared Neighborhood Hits	198
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

B4GN4_HUMAN
θ value	0.00869519 (rank : 185)	NC score	0.044135 (rank : 810)
Query Neighborhood Hits	872	Target Neighborhood Hits	131	Shared Neighborhood Hits	37
SwissProt Accessions	Q76KP1, Q96LV2	Gene names	B4GALNT4
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 1 (EC 2.4.1.244) (NGalNAc-T1) (Beta- 1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4).

CDX1_HUMAN
θ value	0.00869519 (rank : 186)	NC score	0.026502 (rank : 919)
Query Neighborhood Hits	872	Target Neighborhood Hits	382	Shared Neighborhood Hits	47
SwissProt Accessions	P47902, Q4VAU4, Q9NYK8	Gene names	CDX1
Domain Architecture
Description	Homeobox protein CDX-1 (Caudal-type homeobox protein 1).

CSKI2_MOUSE
θ value	0.00869519 (rank : 187)	NC score	0.090547 (rank : 392)
Query Neighborhood Hits	872	Target Neighborhood Hits	812	Shared Neighborhood Hits	230
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

MLL2_HUMAN
θ value	0.00869519 (rank : 188)	NC score	0.125037 (rank : 252)
Query Neighborhood Hits	872	Target Neighborhood Hits	1788	Shared Neighborhood Hits	360
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

NOTC3_MOUSE
θ value	0.00869519 (rank : 189)	NC score	0.021293 (rank : 965)
Query Neighborhood Hits	872	Target Neighborhood Hits	975	Shared Neighborhood Hits	87
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

PDCD7_HUMAN
θ value	0.00869519 (rank : 190)	NC score	0.076089 (rank : 503)
Query Neighborhood Hits	872	Target Neighborhood Hits	255	Shared Neighborhood Hits	60
SwissProt Accessions	Q8N8D1, Q96AK8, Q9Y6D7	Gene names	PDCD7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18) (HES18).

PPIP1_HUMAN
θ value	0.00869519 (rank : 191)	NC score	0.185067 (rank : 126)
Query Neighborhood Hits	872	Target Neighborhood Hits	389	Shared Neighborhood Hits	128
SwissProt Accessions	O43586, O43585, O95657	Gene names	PSTPIP1, CD2BP1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP).

PRR12_HUMAN
θ value	0.00869519 (rank : 192)	NC score	0.134745 (rank : 229)
Query Neighborhood Hits	872	Target Neighborhood Hits	460	Shared Neighborhood Hits	153
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

STAM1_MOUSE
θ value	0.00869519 (rank : 193)	NC score	0.197654 (rank : 110)
Query Neighborhood Hits	872	Target Neighborhood Hits	273	Shared Neighborhood Hits	134
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

SYN1_HUMAN
θ value	0.00869519 (rank : 194)	NC score	0.105033 (rank : 322)
Query Neighborhood Hits	872	Target Neighborhood Hits	419	Shared Neighborhood Hits	147
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

WASL_HUMAN
θ value	0.00869519 (rank : 195)	NC score	0.105298 (rank : 320)
Query Neighborhood Hits	872	Target Neighborhood Hits	312	Shared Neighborhood Hits	118
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

ATX2L_MOUSE
θ value	0.0113563 (rank : 196)	NC score	0.118231 (rank : 271)
Query Neighborhood Hits	872	Target Neighborhood Hits	401	Shared Neighborhood Hits	153
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

CCNK_MOUSE
θ value	0.0113563 (rank : 197)	NC score	0.081075 (rank : 459)
Query Neighborhood Hits	872	Target Neighborhood Hits	350	Shared Neighborhood Hits	113
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

CDX1_MOUSE
θ value	0.0113563 (rank : 198)	NC score	0.027228 (rank : 911)
Query Neighborhood Hits	872	Target Neighborhood Hits	379	Shared Neighborhood Hits	55
SwissProt Accessions	P18111, Q8VCF7	Gene names	Cdx1, Cdx-1
Domain Architecture
Description	Homeobox protein CDX-1 (Caudal-type homeobox protein 1).

CIC_MOUSE
θ value	0.0113563 (rank : 199)	NC score	0.105250 (rank : 321)
Query Neighborhood Hits	872	Target Neighborhood Hits	742	Shared Neighborhood Hits	236
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

DIAP1_HUMAN
θ value	0.0113563 (rank : 200)	NC score	0.084888 (rank : 432)
Query Neighborhood Hits	872	Target Neighborhood Hits	784	Shared Neighborhood Hits	133
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

EPN1_HUMAN
θ value	0.0113563 (rank : 201)	NC score	0.085232 (rank : 430)
Query Neighborhood Hits	872	Target Neighborhood Hits	206	Shared Neighborhood Hits	80
SwissProt Accessions	Q9Y6I3, Q86ST3, Q9HA18	Gene names	EPN1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (EH domain-binding mitotic phosphoprotein).

LDB3_HUMAN
θ value	0.0113563 (rank : 202)	NC score	0.049222 (rank : 785)
Query Neighborhood Hits	872	Target Neighborhood Hits	497	Shared Neighborhood Hits	118
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

MYO1F_MOUSE
θ value	0.0113563 (rank : 203)	NC score	0.119832 (rank : 264)
Query Neighborhood Hits	872	Target Neighborhood Hits	262	Shared Neighborhood Hits	128
SwissProt Accessions	P70248	Gene names	Myo1f
Domain Architecture
Description	Myosin If.

NCOA6_HUMAN
θ value	0.0113563 (rank : 204)	NC score	0.238108 (rank : 75)
Query Neighborhood Hits	872	Target Neighborhood Hits	1202	Shared Neighborhood Hits	420
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

PTN23_HUMAN
θ value	0.0113563 (rank : 205)	NC score	0.057420 (rank : 677)
Query Neighborhood Hits	872	Target Neighborhood Hits	646	Shared Neighborhood Hits	149
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

SH3K1_MOUSE
θ value	0.0113563 (rank : 206)	NC score	0.237182 (rank : 76)
Query Neighborhood Hits	872	Target Neighborhood Hits	332	Shared Neighborhood Hits	144
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

STAM1_HUMAN
θ value	0.0113563 (rank : 207)	NC score	0.198330 (rank : 107)
Query Neighborhood Hits	872	Target Neighborhood Hits	271	Shared Neighborhood Hits	134
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

ARHG7_MOUSE
θ value	0.0148317 (rank : 208)	NC score	0.200787 (rank : 104)
Query Neighborhood Hits	872	Target Neighborhood Hits	396	Shared Neighborhood Hits	135
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

DNMBP_HUMAN
θ value	0.0148317 (rank : 209)	NC score	0.198187 (rank : 109)
Query Neighborhood Hits	872	Target Neighborhood Hits	413	Shared Neighborhood Hits	149
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

HAIR_HUMAN
θ value	0.0148317 (rank : 210)	NC score	0.067080 (rank : 569)
Query Neighborhood Hits	872	Target Neighborhood Hits	172	Shared Neighborhood Hits	73
SwissProt Accessions	O43593, Q96H33, Q9NPE1	Gene names	HR
Domain Architecture
Description	Protein hairless.

MYO15_HUMAN
θ value	0.0148317 (rank : 211)	NC score	0.104593 (rank : 323)
Query Neighborhood Hits	872	Target Neighborhood Hits	671	Shared Neighborhood Hits	286
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

NCK2_HUMAN
θ value	0.0148317 (rank : 212)	NC score	0.207427 (rank : 97)
Query Neighborhood Hits	872	Target Neighborhood Hits	310	Shared Neighborhood Hits	134
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

NOTC2_HUMAN
θ value	0.0148317 (rank : 213)	NC score	0.039811 (rank : 833)
Query Neighborhood Hits	872	Target Neighborhood Hits	1113	Shared Neighborhood Hits	186
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

PRG4_HUMAN
θ value	0.0148317 (rank : 214)	NC score	0.084465 (rank : 437)
Query Neighborhood Hits	872	Target Neighborhood Hits	764	Shared Neighborhood Hits	148
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SFPQ_HUMAN
θ value	0.0148317 (rank : 215)	NC score	0.097028 (rank : 349)
Query Neighborhood Hits	872	Target Neighborhood Hits	986	Shared Neighborhood Hits	205
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

SFPQ_MOUSE
θ value	0.0148317 (rank : 216)	NC score	0.100107 (rank : 333)
Query Neighborhood Hits	872	Target Neighborhood Hits	958	Shared Neighborhood Hits	197
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

SH3K1_HUMAN
θ value	0.0148317 (rank : 217)	NC score	0.236890 (rank : 77)
Query Neighborhood Hits	872	Target Neighborhood Hits	341	Shared Neighborhood Hits	141
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

SRRM1_HUMAN
θ value	0.0148317 (rank : 218)	NC score	0.108431 (rank : 307)
Query Neighborhood Hits	872	Target Neighborhood Hits	690	Shared Neighborhood Hits	142
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

T22D2_HUMAN
θ value	0.0148317 (rank : 219)	NC score	0.095975 (rank : 355)
Query Neighborhood Hits	872	Target Neighborhood Hits	250	Shared Neighborhood Hits	93
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

ZIM10_HUMAN
θ value	0.0148317 (rank : 220)	NC score	0.184556 (rank : 127)
Query Neighborhood Hits	872	Target Neighborhood Hits	577	Shared Neighborhood Hits	287
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ANX11_HUMAN
θ value	0.0193708 (rank : 221)	NC score	0.043687 (rank : 814)
Query Neighborhood Hits	872	Target Neighborhood Hits	192	Shared Neighborhood Hits	64
SwissProt Accessions	P50995	Gene names	ANXA11, ANX11
Domain Architecture
Description	Annexin A11 (Annexin XI) (Calcyclin-associated annexin 50) (CAP-50) (56 kDa autoantigen).

BSN_MOUSE
θ value	0.0193708 (rank : 222)	NC score	0.198218 (rank : 108)
Query Neighborhood Hits	872	Target Neighborhood Hits	2057	Shared Neighborhood Hits	480
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CO8A1_HUMAN
θ value	0.0193708 (rank : 223)	NC score	0.080460 (rank : 465)
Query Neighborhood Hits	872	Target Neighborhood Hits	288	Shared Neighborhood Hits	103
SwissProt Accessions	P27658, Q96D07	Gene names	COL8A1
Domain Architecture
Description	Collagen alpha-1(VIII) chain precursor (Endothelial collagen).

COGA1_HUMAN
θ value	0.0193708 (rank : 224)	NC score	0.090045 (rank : 395)
Query Neighborhood Hits	872	Target Neighborhood Hits	345	Shared Neighborhood Hits	117
SwissProt Accessions	Q07092	Gene names	COL16A1
Domain Architecture
Description	Collagen alpha-1(XVI) chain precursor.

DDEF2_MOUSE
θ value	0.0193708 (rank : 225)	NC score	0.143290 (rank : 207)
Query Neighborhood Hits	872	Target Neighborhood Hits	625	Shared Neighborhood Hits	172
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

GGN_HUMAN
θ value	0.0193708 (rank : 226)	NC score	0.133003 (rank : 233)
Query Neighborhood Hits	872	Target Neighborhood Hits	269	Shared Neighborhood Hits	101
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

IASPP_MOUSE
θ value	0.0193708 (rank : 227)	NC score	0.245350 (rank : 69)
Query Neighborhood Hits	872	Target Neighborhood Hits	1024	Shared Neighborhood Hits	413
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

IRS2_HUMAN
θ value	0.0193708 (rank : 228)	NC score	0.071984 (rank : 528)
Query Neighborhood Hits	872	Target Neighborhood Hits	262	Shared Neighborhood Hits	87
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

NCK1_HUMAN
θ value	0.0193708 (rank : 229)	NC score	0.194766 (rank : 115)
Query Neighborhood Hits	872	Target Neighborhood Hits	312	Shared Neighborhood Hits	131
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

PRRT1_HUMAN
θ value	0.0193708 (rank : 230)	NC score	0.083912 (rank : 444)
Query Neighborhood Hits	872	Target Neighborhood Hits	94	Shared Neighborhood Hits	38
SwissProt Accessions	Q99946, Q96DW3, Q96NQ8	Gene names	PRRT1, C6orf31, NG5
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 1.

RSMB_MOUSE
θ value	0.0193708 (rank : 231)	NC score	0.105385 (rank : 319)
Query Neighborhood Hits	872	Target Neighborhood Hits	93	Shared Neighborhood Hits	40
SwissProt Accessions	P27048, Q3UJT1	Gene names	Snrpb
Domain Architecture
Description	Small nuclear ribonucleoprotein-associated protein B (snRNP-B) (Sm protein B) (Sm-B) (SmB).

SEM6C_HUMAN
θ value	0.0193708 (rank : 232)	NC score	0.018141 (rank : 987)
Query Neighborhood Hits	872	Target Neighborhood Hits	117	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H3T2, Q5JR71, Q8WXT8, Q8WXT9, Q8WXU0, Q96JF8	Gene names	SEMA6C, KIAA1869, SEMAY
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

WASF3_HUMAN
θ value	0.0193708 (rank : 233)	NC score	0.114671 (rank : 286)
Query Neighborhood Hits	872	Target Neighborhood Hits	204	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UPY6, O94974	Gene names	WASF3, KIAA0900, SCAR3, WAVE3
Domain Architecture
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3) (Verprolin homology domain-containing protein 3).

YLPM1_MOUSE
θ value	0.0193708 (rank : 234)	NC score	0.125903 (rank : 250)
Query Neighborhood Hits	872	Target Neighborhood Hits	505	Shared Neighborhood Hits	152
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

ABI2_MOUSE
θ value	0.0252991 (rank : 235)	NC score	0.207681 (rank : 95)
Query Neighborhood Hits	872	Target Neighborhood Hits	266	Shared Neighborhood Hits	142
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

CASZ1_HUMAN
θ value	0.0252991 (rank : 236)	NC score	0.035476 (rank : 862)
Query Neighborhood Hits	872	Target Neighborhood Hits	473	Shared Neighborhood Hits	38
SwissProt Accessions	Q86V15, Q5T9S1, Q8WX49, Q8WX50, Q9BT16, Q9NXC6	Gene names	CASZ1, CST, ZNF693
Domain Architecture	No domain graphic available
Description	Castor homolog 1 zinc finger protein (Castor-related protein) (Zinc finger protein 693).

CO8A1_MOUSE
θ value	0.0252991 (rank : 237)	NC score	0.078117 (rank : 484)
Query Neighborhood Hits	872	Target Neighborhood Hits	251	Shared Neighborhood Hits	95
SwissProt Accessions	Q00780, Q9D2V4	Gene names	Col8a1
Domain Architecture
Description	Collagen alpha-1(VIII) chain precursor.

DOT1L_HUMAN
θ value	0.0252991 (rank : 238)	NC score	0.109284 (rank : 303)
Query Neighborhood Hits	872	Target Neighborhood Hits	660	Shared Neighborhood Hits	158
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

GRAP2_HUMAN
θ value	0.0252991 (rank : 239)	NC score	0.202464 (rank : 101)
Query Neighborhood Hits	872	Target Neighborhood Hits	304	Shared Neighborhood Hits	138
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

NGEF_HUMAN
θ value	0.0252991 (rank : 240)	NC score	0.112621 (rank : 292)
Query Neighborhood Hits	872	Target Neighborhood Hits	166	Shared Neighborhood Hits	76
SwissProt Accessions	Q8N5V2, Q53QQ4, Q53ST7, Q6GMQ5, Q9NQD6	Gene names	NGEF
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

PAF49_HUMAN
θ value	0.0252991 (rank : 241)	NC score	0.068046 (rank : 561)
Query Neighborhood Hits	872	Target Neighborhood Hits	169	Shared Neighborhood Hits	38
SwissProt Accessions	O15446, Q32N11, Q7Z5U2, Q9UPF6	Gene names	CD3EAP, ASE1, CAST, PAF49
Domain Architecture	No domain graphic available
Description	RNA polymerase I-associated factor PAF49 (Anti-sense to ERCC-1 protein) (ASE-1) (CD3-epsilon-associated protein) (CD3E-associated protein) (CAST).

SNIP_MOUSE
θ value	0.0252991 (rank : 242)	NC score	0.051602 (rank : 758)
Query Neighborhood Hits	872	Target Neighborhood Hits	319	Shared Neighborhood Hits	67
SwissProt Accessions	Q9QWI6, O70298	Gene names	P140, Kiaa1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

SRRM1_MOUSE
θ value	0.0252991 (rank : 243)	NC score	0.146670 (rank : 201)
Query Neighborhood Hits	872	Target Neighborhood Hits	966	Shared Neighborhood Hits	240
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SSBP4_HUMAN
θ value	0.0252991 (rank : 244)	NC score	0.244849 (rank : 70)
Query Neighborhood Hits	872	Target Neighborhood Hits	753	Shared Neighborhood Hits	370
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

STON1_MOUSE
θ value	0.0252991 (rank : 245)	NC score	0.047040 (rank : 796)
Query Neighborhood Hits	872	Target Neighborhood Hits	50	Shared Neighborhood Hits	17
SwissProt Accessions	Q8CDJ8, Q8CDL8, Q9D5T3	Gene names	Ston1, Salf, Sblf, Stn1
Domain Architecture
Description	Stonin-1 (Stoned B-like factor).

TSC1_HUMAN
θ value	0.0252991 (rank : 246)	NC score	0.050516 (rank : 776)
Query Neighborhood Hits	872	Target Neighborhood Hits	765	Shared Neighborhood Hits	97
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

ZN207_HUMAN
θ value	0.0252991 (rank : 247)	NC score	0.102338 (rank : 329)
Query Neighborhood Hits	872	Target Neighborhood Hits	326	Shared Neighborhood Hits	75
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

ARHG7_HUMAN
θ value	0.0330416 (rank : 248)	NC score	0.195541 (rank : 113)
Query Neighborhood Hits	872	Target Neighborhood Hits	347	Shared Neighborhood Hits	137
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

CIC_HUMAN
θ value	0.0330416 (rank : 249)	NC score	0.157450 (rank : 175)
Query Neighborhood Hits	872	Target Neighborhood Hits	992	Shared Neighborhood Hits	346
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

DCC_MOUSE
θ value	0.0330416 (rank : 250)	NC score	0.051915 (rank : 753)
Query Neighborhood Hits	872	Target Neighborhood Hits	896	Shared Neighborhood Hits	206
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

GRAP2_MOUSE
θ value	0.0330416 (rank : 251)	NC score	0.201163 (rank : 103)
Query Neighborhood Hits	872	Target Neighborhood Hits	297	Shared Neighborhood Hits	137
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

KLF2_MOUSE
θ value	0.0330416 (rank : 252)	NC score	0.006118 (rank : 1084)
Query Neighborhood Hits	872	Target Neighborhood Hits	738	Shared Neighborhood Hits	60
SwissProt Accessions	Q60843	Gene names	Klf2, Lklf
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 2 (Lung krueppel-like factor).

NR4A3_MOUSE
θ value	0.0330416 (rank : 253)	NC score	0.013281 (rank : 1020)
Query Neighborhood Hits	872	Target Neighborhood Hits	127	Shared Neighborhood Hits	16
SwissProt Accessions	Q9QZB6, Q9QZB5	Gene names	Nr4a3, Tec
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Orphan nuclear receptor TEC) (Translocated in extraskeletal chondrosarcoma).

PTN23_MOUSE
θ value	0.0330416 (rank : 254)	NC score	0.060996 (rank : 629)
Query Neighborhood Hits	872	Target Neighborhood Hits	726	Shared Neighborhood Hits	183
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

SMRC1_HUMAN
θ value	0.0330416 (rank : 255)	NC score	0.088983 (rank : 401)
Query Neighborhood Hits	872	Target Neighborhood Hits	375	Shared Neighborhood Hits	80
SwissProt Accessions	Q92922, Q6P172, Q8IWH2	Gene names	SMARCC1, BAF155
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155).

VAV2_MOUSE
θ value	0.0330416 (rank : 256)	NC score	0.183384 (rank : 131)
Query Neighborhood Hits	872	Target Neighborhood Hits	456	Shared Neighborhood Hits	159
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

BAT3_MOUSE
θ value	0.0431538 (rank : 257)	NC score	0.143810 (rank : 204)
Query Neighborhood Hits	872	Target Neighborhood Hits	518	Shared Neighborhood Hits	228
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

CAC1A_HUMAN
θ value	0.0431538 (rank : 258)	NC score	0.035620 (rank : 861)
Query Neighborhood Hits	872	Target Neighborhood Hits	387	Shared Neighborhood Hits	129
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CBP_MOUSE
θ value	0.0431538 (rank : 259)	NC score	0.156068 (rank : 182)
Query Neighborhood Hits	872	Target Neighborhood Hits	1051	Shared Neighborhood Hits	333
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CRX_HUMAN
θ value	0.0431538 (rank : 260)	NC score	0.021845 (rank : 956)
Query Neighborhood Hits	872	Target Neighborhood Hits	360	Shared Neighborhood Hits	38
SwissProt Accessions	O43186	Gene names	CRX, CORD2
Domain Architecture
Description	Cone-rod homeobox protein.

GLI1_HUMAN
θ value	0.0431538 (rank : 261)	NC score	0.006212 (rank : 1082)
Query Neighborhood Hits	872	Target Neighborhood Hits	828	Shared Neighborhood Hits	86
SwissProt Accessions	P08151, Q8TDN9	Gene names	GLI1, GLI
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI1 (Glioma-associated oncogene) (Oncogene GLI).

GNAS1_HUMAN
θ value	0.0431538 (rank : 262)	NC score	0.037025 (rank : 854)
Query Neighborhood Hits	872	Target Neighborhood Hits	278	Shared Neighborhood Hits	91
SwissProt Accessions	Q5JWF2, O75684, O75685, Q5JW67, Q5JWF1, Q9NY42	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

K1543_MOUSE
θ value	0.0431538 (rank : 263)	NC score	0.136924 (rank : 221)
Query Neighborhood Hits	872	Target Neighborhood Hits	497	Shared Neighborhood Hits	186
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

NGEF_MOUSE
θ value	0.0431538 (rank : 264)	NC score	0.114614 (rank : 287)
Query Neighborhood Hits	872	Target Neighborhood Hits	228	Shared Neighborhood Hits	93
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

PDZD2_HUMAN
θ value	0.0431538 (rank : 265)	NC score	0.084428 (rank : 439)
Query Neighborhood Hits	872	Target Neighborhood Hits	772	Shared Neighborhood Hits	198
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

PRRT1_MOUSE
θ value	0.0431538 (rank : 266)	NC score	0.084795 (rank : 434)
Query Neighborhood Hits	872	Target Neighborhood Hits	102	Shared Neighborhood Hits	40
SwissProt Accessions	O35449	Gene names	Prrt1, Ng5
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 1.

SFR15_HUMAN
θ value	0.0431538 (rank : 267)	NC score	0.098123 (rank : 341)
Query Neighborhood Hits	872	Target Neighborhood Hits	368	Shared Neighborhood Hits	106
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

SH22A_HUMAN
θ value	0.0431538 (rank : 268)	NC score	0.054661 (rank : 717)
Query Neighborhood Hits	872	Target Neighborhood Hits	144	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NP31, O43817, Q9UPA7	Gene names	SH2D2A, SCAP, TSAD, VRAP
Domain Architecture
Description	SH2 domain protein 2A (T cell-specific adapter protein) (TSAd) (VEGF receptor-associated protein) (SH2 domain-containing adapter protein).

STAC_MOUSE
θ value	0.0431538 (rank : 269)	NC score	0.218230 (rank : 87)
Query Neighborhood Hits	872	Target Neighborhood Hits	268	Shared Neighborhood Hits	127
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

TREF1_MOUSE
θ value	0.0431538 (rank : 270)	NC score	0.039012 (rank : 842)
Query Neighborhood Hits	872	Target Neighborhood Hits	682	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BXJ2, Q6PCQ4, Q80X25, Q810H8, Q8BY31	Gene names	Trerf1
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132).

VAV2_HUMAN
θ value	0.0431538 (rank : 271)	NC score	0.179803 (rank : 135)
Query Neighborhood Hits	872	Target Neighborhood Hits	453	Shared Neighborhood Hits	145
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

ARHG4_MOUSE
θ value	0.0563607 (rank : 272)	NC score	0.157439 (rank : 176)
Query Neighborhood Hits	872	Target Neighborhood Hits	185	Shared Neighborhood Hits	101
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ARHG6_MOUSE
θ value	0.0563607 (rank : 273)	NC score	0.184203 (rank : 129)
Query Neighborhood Hits	872	Target Neighborhood Hits	394	Shared Neighborhood Hits	129
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

BTBD7_MOUSE
θ value	0.0563607 (rank : 274)	NC score	0.037885 (rank : 845)
Query Neighborhood Hits	872	Target Neighborhood Hits	228	Shared Neighborhood Hits	40
SwissProt Accessions	Q8CFE5, Q80TC3, Q8BZY9	Gene names	Btbd7, Kiaa1525
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 7.

CO1A2_MOUSE
θ value	0.0563607 (rank : 275)	NC score	0.096393 (rank : 353)
Query Neighborhood Hits	872	Target Neighborhood Hits	388	Shared Neighborhood Hits	136
SwissProt Accessions	Q01149, Q8CGA5	Gene names	Col1a2, Cola2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

CO5A1_MOUSE
θ value	0.0563607 (rank : 276)	NC score	0.089170 (rank : 399)
Query Neighborhood Hits	872	Target Neighborhood Hits	419	Shared Neighborhood Hits	139
SwissProt Accessions	O88207	Gene names	Col5a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(V) chain precursor.

CT032_HUMAN
θ value	0.0563607 (rank : 277)	NC score	0.173346 (rank : 144)
Query Neighborhood Hits	872	Target Neighborhood Hits	235	Shared Neighborhood Hits	127
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

DNMBP_MOUSE
θ value	0.0563607 (rank : 278)	NC score	0.196510 (rank : 111)
Query Neighborhood Hits	872	Target Neighborhood Hits	435	Shared Neighborhood Hits	159
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

MAST3_HUMAN
θ value	0.0563607 (rank : 279)	NC score	0.004768 (rank : 1097)
Query Neighborhood Hits	872	Target Neighborhood Hits	1128	Shared Neighborhood Hits	114
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

MISS_MOUSE
θ value	0.0563607 (rank : 280)	NC score	0.239672 (rank : 73)
Query Neighborhood Hits	872	Target Neighborhood Hits	444	Shared Neighborhood Hits	261
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

PPIP1_MOUSE
θ value	0.0563607 (rank : 281)	NC score	0.177444 (rank : 136)
Query Neighborhood Hits	872	Target Neighborhood Hits	377	Shared Neighborhood Hits	128
SwissProt Accessions	P97814, Q4V9R4	Gene names	Pstpip1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1).

R3HD1_HUMAN
θ value	0.0563607 (rank : 282)	NC score	0.064767 (rank : 590)
Query Neighborhood Hits	872	Target Neighborhood Hits	203	Shared Neighborhood Hits	66
SwissProt Accessions	Q15032, Q8IW32	Gene names	R3HDM1, KIAA0029, R3HDM
Domain Architecture	No domain graphic available
Description	R3H domain-containing protein 1.

RERE_MOUSE
θ value	0.0563607 (rank : 283)	NC score	0.126389 (rank : 248)
Query Neighborhood Hits	872	Target Neighborhood Hits	785	Shared Neighborhood Hits	211
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

SOS1_HUMAN
θ value	0.0563607 (rank : 284)	NC score	0.067990 (rank : 563)
Query Neighborhood Hits	872	Target Neighborhood Hits	274	Shared Neighborhood Hits	79
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

STAC_HUMAN
θ value	0.0563607 (rank : 285)	NC score	0.215944 (rank : 89)
Query Neighborhood Hits	872	Target Neighborhood Hits	276	Shared Neighborhood Hits	124
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

VAV_HUMAN
θ value	0.0563607 (rank : 286)	NC score	0.176622 (rank : 139)
Query Neighborhood Hits	872	Target Neighborhood Hits	452	Shared Neighborhood Hits	140
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

VAV_MOUSE
θ value	0.0563607 (rank : 287)	NC score	0.180144 (rank : 134)
Query Neighborhood Hits	872	Target Neighborhood Hits	430	Shared Neighborhood Hits	140
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

WNK4_HUMAN
θ value	0.0563607 (rank : 288)	NC score	0.016176 (rank : 996)
Query Neighborhood Hits	872	Target Neighborhood Hits	1043	Shared Neighborhood Hits	127
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

ALEX_HUMAN
θ value	0.0736092 (rank : 289)	NC score	0.123597 (rank : 254)
Query Neighborhood Hits	872	Target Neighborhood Hits	361	Shared Neighborhood Hits	134
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

ANXA7_HUMAN
θ value	0.0736092 (rank : 290)	NC score	0.044060 (rank : 811)
Query Neighborhood Hits	872	Target Neighborhood Hits	168	Shared Neighborhood Hits	61
SwissProt Accessions	P20073	Gene names	ANXA7, ANX7, SNX
Domain Architecture
Description	Annexin A7 (Annexin VII) (Synexin).

CTGE5_MOUSE
θ value	0.0736092 (rank : 291)	NC score	0.015144 (rank : 1001)
Query Neighborhood Hits	872	Target Neighborhood Hits	928	Shared Neighborhood Hits	69
SwissProt Accessions	Q8R311, Q8CIE3	Gene names	Ctage5, Mea6, Mgea6
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 5 homolog (cTAGE-5 protein) (Meningioma-expressed antigen 6).

DRD4_HUMAN
θ value	0.0736092 (rank : 292)	NC score	-0.005702 (rank : 1139)
Query Neighborhood Hits	872	Target Neighborhood Hits	886	Shared Neighborhood Hits	27
SwissProt Accessions	P21917	Gene names	DRD4
Domain Architecture
Description	D(4) dopamine receptor (Dopamine D4 receptor) (D(2C) dopamine receptor).

EMID2_MOUSE
θ value	0.0736092 (rank : 293)	NC score	0.076306 (rank : 501)
Query Neighborhood Hits	872	Target Neighborhood Hits	201	Shared Neighborhood Hits	86
SwissProt Accessions	Q91VF6, Q8K4P3	Gene names	Emid2, Col26a, Col26a1, Emu2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXVI) chain precursor (EMI domain-containing protein 2) (Protein Emu2) (Emilin and multimerin domain-containing protein 2).

FMN2_MOUSE
θ value	0.0736092 (rank : 294)	NC score	0.110285 (rank : 301)
Query Neighborhood Hits	872	Target Neighborhood Hits	349	Shared Neighborhood Hits	129
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

M3KL4_HUMAN
θ value	0.0736092 (rank : 295)	NC score	0.041941 (rank : 819)
Query Neighborhood Hits	872	Target Neighborhood Hits	1087	Shared Neighborhood Hits	140
SwissProt Accessions	Q5TCX8, Q5TCX7, Q5TCX9, Q8WWN1, Q8WWN2, Q96JM1	Gene names	MLK4, KIAA1804
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase 4).

MAGC3_HUMAN
θ value	0.0736092 (rank : 296)	NC score	0.017741 (rank : 991)
Query Neighborhood Hits	872	Target Neighborhood Hits	71	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TD91, Q5JZ43, Q9BZ80	Gene names	MAGEC3, HCA2
Domain Architecture
Description	Melanoma-associated antigen C3 (MAGE-C3 antigen) (Hepatocellular carcinoma-associated antigen 2).

RGS3_MOUSE
θ value	0.0736092 (rank : 297)	NC score	0.221747 (rank : 83)
Query Neighborhood Hits	872	Target Neighborhood Hits	1621	Shared Neighborhood Hits	497
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SC24A_MOUSE
θ value	0.0736092 (rank : 298)	NC score	0.140675 (rank : 211)
Query Neighborhood Hits	872	Target Neighborhood Hits	394	Shared Neighborhood Hits	207
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

SSXT_MOUSE
θ value	0.0736092 (rank : 299)	NC score	0.059491 (rank : 649)
Query Neighborhood Hits	872	Target Neighborhood Hits	118	Shared Neighborhood Hits	46
SwissProt Accessions	Q62280	Gene names	Ss18, Ssxt, Syt
Domain Architecture
Description	SSXT protein (SYT protein) (Synovial sarcoma-associated Ss18-alpha).

VINEX_MOUSE
θ value	0.0736092 (rank : 300)	NC score	0.213793 (rank : 91)
Query Neighborhood Hits	872	Target Neighborhood Hits	286	Shared Neighborhood Hits	144
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

WASF1_MOUSE
θ value	0.0736092 (rank : 301)	NC score	0.118780 (rank : 269)
Query Neighborhood Hits	872	Target Neighborhood Hits	261	Shared Neighborhood Hits	106
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

ABI1_HUMAN
θ value	0.0961366 (rank : 302)	NC score	0.193288 (rank : 118)
Query Neighborhood Hits	872	Target Neighborhood Hits	257	Shared Neighborhood Hits	153
SwissProt Accessions	Q8IZP0, O15147, O76049, O95060, Q5W070, Q5W072, Q8TB63, Q96S81, Q9NXZ9, Q9NYB8	Gene names	ABI1, SSH3BP1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Nap1-binding protein) (Nap1BP) (Abl-binding protein 4) (AblBP4).

ALO17_HUMAN
θ value	0.0961366 (rank : 303)	NC score	0.065751 (rank : 582)
Query Neighborhood Hits	872	Target Neighborhood Hits	317	Shared Neighborhood Hits	48
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

BCL9_HUMAN
θ value	0.0961366 (rank : 304)	NC score	0.261874 (rank : 66)
Query Neighborhood Hits	872	Target Neighborhood Hits	1008	Shared Neighborhood Hits	417
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

CO1A1_MOUSE
θ value	0.0961366 (rank : 305)	NC score	0.096247 (rank : 354)
Query Neighborhood Hits	872	Target Neighborhood Hits	457	Shared Neighborhood Hits	148
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CO5A3_HUMAN
θ value	0.0961366 (rank : 306)	NC score	0.092440 (rank : 379)
Query Neighborhood Hits	872	Target Neighborhood Hits	433	Shared Neighborhood Hits	141
SwissProt Accessions	P25940, Q9NZQ6	Gene names	COL5A3
Domain Architecture
Description	Collagen alpha-3(V) chain precursor.

ETV5_MOUSE
θ value	0.0961366 (rank : 307)	NC score	0.056453 (rank : 688)
Query Neighborhood Hits	872	Target Neighborhood Hits	328	Shared Neighborhood Hits	148
SwissProt Accessions	Q9CXC9, Q3TG49, Q8C0F3, Q9JHB1	Gene names	Etv5
Domain Architecture	No domain graphic available
Description	ETS translocation variant 5.

FA53C_MOUSE
θ value	0.0961366 (rank : 308)	NC score	0.037270 (rank : 850)
Query Neighborhood Hits	872	Target Neighborhood Hits	40	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BXQ8, Q3U4J2	Gene names	Fam53c
Domain Architecture	No domain graphic available
Description	Protein FAM53C.

HHEX_MOUSE
θ value	0.0961366 (rank : 309)	NC score	0.018284 (rank : 985)
Query Neighborhood Hits	872	Target Neighborhood Hits	350	Shared Neighborhood Hits	31
SwissProt Accessions	P43120	Gene names	Hhex, Prhx
Domain Architecture
Description	Homeobox protein PRH (Hematopoietically expressed homeobox) (Homeobox protein HEX).

MILK1_MOUSE
θ value	0.0961366 (rank : 310)	NC score	0.098758 (rank : 336)
Query Neighborhood Hits	872	Target Neighborhood Hits	788	Shared Neighborhood Hits	268
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

PER1_MOUSE
θ value	0.0961366 (rank : 311)	NC score	0.044844 (rank : 803)
Query Neighborhood Hits	872	Target Neighborhood Hits	235	Shared Neighborhood Hits	86
SwissProt Accessions	O35973	Gene names	Per1, Per, Rigui
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (mPER) (M-Rigui).

SH23A_HUMAN
θ value	0.0961366 (rank : 312)	NC score	0.050572 (rank : 775)
Query Neighborhood Hits	872	Target Neighborhood Hits	149	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BRG2, Q9Y2X4	Gene names	SH2D3A, NSP1
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3A (Novel SH2-containing protein 1).

SMRC1_MOUSE
θ value	0.0961366 (rank : 313)	NC score	0.087710 (rank : 409)
Query Neighborhood Hits	872	Target Neighborhood Hits	459	Shared Neighborhood Hits	87
SwissProt Accessions	P97496, Q7TS80, Q7TT29	Gene names	Smarcc1, Baf155, Srg3
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155) (SWI3-related protein).

SOX17_MOUSE
θ value	0.0961366 (rank : 314)	NC score	0.039217 (rank : 839)
Query Neighborhood Hits	872	Target Neighborhood Hits	223	Shared Neighborhood Hits	90
SwissProt Accessions	Q61473, Q61472, Q62248	Gene names	Sox17, Sox-17
Domain Architecture
Description	Transcription factor SOX-17.

SRBP1_MOUSE
θ value	0.0961366 (rank : 315)	NC score	0.094083 (rank : 361)
Query Neighborhood Hits	872	Target Neighborhood Hits	384	Shared Neighborhood Hits	161
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

WASF1_HUMAN
θ value	0.0961366 (rank : 316)	NC score	0.116803 (rank : 277)
Query Neighborhood Hits	872	Target Neighborhood Hits	260	Shared Neighborhood Hits	108
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

ARI1A_HUMAN
θ value	0.125558 (rank : 317)	NC score	0.162326 (rank : 166)
Query Neighborhood Hits	872	Target Neighborhood Hits	787	Shared Neighborhood Hits	276
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

ATX2_HUMAN
θ value	0.125558 (rank : 318)	NC score	0.093880 (rank : 366)
Query Neighborhood Hits	872	Target Neighborhood Hits	375	Shared Neighborhood Hits	114
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

ATX2_MOUSE
θ value	0.125558 (rank : 319)	NC score	0.112307 (rank : 294)
Query Neighborhood Hits	872	Target Neighborhood Hits	445	Shared Neighborhood Hits	161
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

CO5A1_HUMAN
θ value	0.125558 (rank : 320)	NC score	0.091091 (rank : 387)
Query Neighborhood Hits	872	Target Neighborhood Hits	434	Shared Neighborhood Hits	142
SwissProt Accessions	P20908, Q15094, Q5SUX4	Gene names	COL5A1
Domain Architecture
Description	Collagen alpha-1(V) chain precursor.

MLL3_HUMAN
θ value	0.125558 (rank : 321)	NC score	0.172278 (rank : 146)
Query Neighborhood Hits	872	Target Neighborhood Hits	1644	Shared Neighborhood Hits	400
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

NKX61_HUMAN
θ value	0.125558 (rank : 322)	NC score	0.028966 (rank : 898)
Query Neighborhood Hits	872	Target Neighborhood Hits	431	Shared Neighborhood Hits	60
SwissProt Accessions	P78426	Gene names	NKX6-1, NKX6A
Domain Architecture
Description	Homeobox protein Nkx-6.1.

RBM12_MOUSE
θ value	0.125558 (rank : 323)	NC score	0.076743 (rank : 495)
Query Neighborhood Hits	872	Target Neighborhood Hits	313	Shared Neighborhood Hits	107
SwissProt Accessions	Q8R4X3, Q8K373, Q8R302, Q9CS80	Gene names	Rbm12
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

SNX22_HUMAN
θ value	0.125558 (rank : 324)	NC score	0.058925 (rank : 656)
Query Neighborhood Hits	872	Target Neighborhood Hits	31	Shared Neighborhood Hits	6
SwissProt Accessions	Q96L94, Q9H844	Gene names	SNX22
Domain Architecture
Description	Sorting nexin-22.

SOS1_MOUSE
θ value	0.125558 (rank : 325)	NC score	0.064804 (rank : 589)
Query Neighborhood Hits	872	Target Neighborhood Hits	281	Shared Neighborhood Hits	75
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

SSXT_HUMAN
θ value	0.125558 (rank : 326)	NC score	0.059094 (rank : 655)
Query Neighborhood Hits	872	Target Neighborhood Hits	125	Shared Neighborhood Hits	48
SwissProt Accessions	Q15532, Q16404, Q9BXC6	Gene names	SS18, SSXT, SYT
Domain Architecture
Description	SSXT protein (Synovial sarcoma, translocated to X chromosome) (SYT protein).

STON2_HUMAN
θ value	0.125558 (rank : 327)	NC score	0.039066 (rank : 841)
Query Neighborhood Hits	872	Target Neighborhood Hits	115	Shared Neighborhood Hits	29
SwissProt Accessions	Q8WXE9, Q6NT47, Q96RI7, Q96RU6	Gene names	STON2, STN2, STNB
Domain Architecture
Description	Stonin-2 (Stoned B).

SYNJ1_MOUSE
θ value	0.125558 (rank : 328)	NC score	0.104261 (rank : 324)
Query Neighborhood Hits	872	Target Neighborhood Hits	516	Shared Neighborhood Hits	182
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

ADA19_MOUSE
θ value	0.163984 (rank : 329)	NC score	0.007896 (rank : 1074)
Query Neighborhood Hits	872	Target Neighborhood Hits	315	Shared Neighborhood Hits	32
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

ALEX_MOUSE
θ value	0.163984 (rank : 330)	NC score	0.080835 (rank : 461)
Query Neighborhood Hits	872	Target Neighborhood Hits	197	Shared Neighborhood Hits	72
SwissProt Accessions	Q6R0H6, Q8BIR3	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

ANX11_MOUSE
θ value	0.163984 (rank : 331)	NC score	0.043445 (rank : 815)
Query Neighborhood Hits	872	Target Neighborhood Hits	200	Shared Neighborhood Hits	73
SwissProt Accessions	P97384	Gene names	Anxa11, Anx11
Domain Architecture
Description	Annexin A11 (Annexin XI) (Calcyclin-associated annexin 50) (CAP-50).

BAI2_HUMAN
θ value	0.163984 (rank : 332)	NC score	0.012703 (rank : 1029)
Query Neighborhood Hits	872	Target Neighborhood Hits	332	Shared Neighborhood Hits	61
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BCL9_MOUSE
θ value	0.163984 (rank : 333)	NC score	0.213808 (rank : 90)
Query Neighborhood Hits	872	Target Neighborhood Hits	770	Shared Neighborhood Hits	349
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

BORG3_HUMAN
θ value	0.163984 (rank : 334)	NC score	0.037349 (rank : 848)
Query Neighborhood Hits	872	Target Neighborhood Hits	36	Shared Neighborhood Hits	13
SwissProt Accessions	Q6NZY7, Q8TB51	Gene names	CDC42EP5, BORG3, CEP5
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 5 (Binder of Rho GTPases 3).

CO9A1_HUMAN
θ value	0.163984 (rank : 335)	NC score	0.091110 (rank : 386)
Query Neighborhood Hits	872	Target Neighborhood Hits	420	Shared Neighborhood Hits	137
SwissProt Accessions	P20849, Q13699, Q13700, Q5TF52, Q6P467, Q96BM8, Q99225, Q9H151, Q9H152, Q9Y6P2, Q9Y6P3	Gene names	COL9A1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

CO9A3_HUMAN
θ value	0.163984 (rank : 336)	NC score	0.091320 (rank : 383)
Query Neighborhood Hits	872	Target Neighborhood Hits	361	Shared Neighborhood Hits	135
SwissProt Accessions	Q14050, Q13681, Q9H4G9, Q9UPE2	Gene names	COL9A3
Domain Architecture	No domain graphic available
Description	Collagen alpha-3(IX) chain precursor.

CRX_MOUSE
θ value	0.163984 (rank : 337)	NC score	0.017440 (rank : 992)
Query Neighborhood Hits	872	Target Neighborhood Hits	359	Shared Neighborhood Hits	31
SwissProt Accessions	O54751	Gene names	Crx
Domain Architecture
Description	Cone-rod homeobox protein.

DMRTC_HUMAN
θ value	0.163984 (rank : 338)	NC score	0.039956 (rank : 832)
Query Neighborhood Hits	872	Target Neighborhood Hits	15	Shared Neighborhood Hits	5
SwissProt Accessions	Q5HYR2, Q5HYR0, Q5U5K2, Q8N6L3, Q96SD3	Gene names	DMRTC1
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C1.

GRB2_HUMAN
θ value	0.163984 (rank : 339)	NC score	0.203802 (rank : 99)
Query Neighborhood Hits	872	Target Neighborhood Hits	310	Shared Neighborhood Hits	136
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
θ value	0.163984 (rank : 340)	NC score	0.203568 (rank : 100)
Query Neighborhood Hits	872	Target Neighborhood Hits	312	Shared Neighborhood Hits	136
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

HME1_MOUSE
θ value	0.163984 (rank : 341)	NC score	0.021857 (rank : 955)
Query Neighborhood Hits	872	Target Neighborhood Hits	397	Shared Neighborhood Hits	55
SwissProt Accessions	P09065	Gene names	En1, En-1
Domain Architecture
Description	Homeobox protein engrailed-1 (Mo-En-1).

IQEC2_HUMAN
θ value	0.163984 (rank : 342)	NC score	0.048635 (rank : 788)
Query Neighborhood Hits	872	Target Neighborhood Hits	403	Shared Neighborhood Hits	108
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IQEC2_MOUSE
θ value	0.163984 (rank : 343)	NC score	0.049464 (rank : 784)
Query Neighborhood Hits	872	Target Neighborhood Hits	417	Shared Neighborhood Hits	110
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

LDB3_MOUSE
θ value	0.163984 (rank : 344)	NC score	0.044172 (rank : 807)
Query Neighborhood Hits	872	Target Neighborhood Hits	510	Shared Neighborhood Hits	118
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

LRP5_HUMAN
θ value	0.163984 (rank : 345)	NC score	0.012561 (rank : 1032)
Query Neighborhood Hits	872	Target Neighborhood Hits	224	Shared Neighborhood Hits	15
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

LRP5_MOUSE
θ value	0.163984 (rank : 346)	NC score	0.013069 (rank : 1023)
Query Neighborhood Hits	872	Target Neighborhood Hits	236	Shared Neighborhood Hits	19
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

MUC7_HUMAN
θ value	0.163984 (rank : 347)	NC score	0.115032 (rank : 283)
Query Neighborhood Hits	872	Target Neighborhood Hits	538	Shared Neighborhood Hits	144
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

NBL1_HUMAN
θ value	0.163984 (rank : 348)	NC score	0.041675 (rank : 821)
Query Neighborhood Hits	872	Target Neighborhood Hits	22	Shared Neighborhood Hits	5
SwissProt Accessions	P41271, Q96L68	Gene names	NBL1, DAN
Domain Architecture
Description	Neuroblastoma suppressor of tumorigenicity 1 precursor (Zinc finger protein DAN) (N03).

NKX61_MOUSE
θ value	0.163984 (rank : 349)	NC score	0.028504 (rank : 903)
Query Neighborhood Hits	872	Target Neighborhood Hits	439	Shared Neighborhood Hits	63
SwissProt Accessions	Q99MA9, Q9ERQ7	Gene names	Nkx6-1, Nkx6.1, Nkx6a
Domain Architecture
Description	Homeobox protein Nkx-6.1.

NLGN2_HUMAN
θ value	0.163984 (rank : 350)	NC score	0.014794 (rank : 1005)
Query Neighborhood Hits	872	Target Neighborhood Hits	55	Shared Neighborhood Hits	17
SwissProt Accessions	Q8NFZ4, Q9P2I1	Gene names	NLGN2, KIAA1366
Domain Architecture
Description	Neuroligin-2 precursor.

NLGN2_MOUSE
θ value	0.163984 (rank : 351)	NC score	0.013975 (rank : 1013)
Query Neighborhood Hits	872	Target Neighborhood Hits	49	Shared Neighborhood Hits	12
SwissProt Accessions	Q69ZK9, Q5F288	Gene names	Nlgn2, Kiaa1366
Domain Architecture	No domain graphic available
Description	Neuroligin-2 precursor.

RXRB_MOUSE
θ value	0.163984 (rank : 352)	NC score	0.020317 (rank : 971)
Query Neighborhood Hits	872	Target Neighborhood Hits	230	Shared Neighborhood Hits	68
SwissProt Accessions	P28704, P33243	Gene names	Rxrb, Nr2b2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta) (MHC class I regulatory element-binding protein H-2RIIBP).

RX_HUMAN
θ value	0.163984 (rank : 353)	NC score	0.020592 (rank : 969)
Query Neighborhood Hits	872	Target Neighborhood Hits	423	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y2V3	Gene names	RAX, RX
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

SHAN2_MOUSE
θ value	0.163984 (rank : 354)	NC score	0.109209 (rank : 304)
Query Neighborhood Hits	872	Target Neighborhood Hits	446	Shared Neighborhood Hits	135
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

VINEX_HUMAN
θ value	0.163984 (rank : 355)	NC score	0.206932 (rank : 98)
Query Neighborhood Hits	872	Target Neighborhood Hits	270	Shared Neighborhood Hits	141
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

ZDHC1_HUMAN
θ value	0.163984 (rank : 356)	NC score	0.028258 (rank : 909)
Query Neighborhood Hits	872	Target Neighborhood Hits	84	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WTX9, O15461	Gene names	ZDHHC1, C16orf1, ZNF377
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC1 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 1) (DHHC-1) (Zinc finger protein 377) (DHHC- domain-containing cysteine-rich protein 1).

ABI2_HUMAN
θ value	0.21417 (rank : 357)	NC score	0.218305 (rank : 86)
Query Neighborhood Hits	872	Target Neighborhood Hits	350	Shared Neighborhood Hits	176
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

ATBF1_MOUSE
θ value	0.21417 (rank : 358)	NC score	0.034256 (rank : 865)
Query Neighborhood Hits	872	Target Neighborhood Hits	1841	Shared Neighborhood Hits	199
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

ATX2L_HUMAN
θ value	0.21417 (rank : 359)	NC score	0.112765 (rank : 291)
Query Neighborhood Hits	872	Target Neighborhood Hits	443	Shared Neighborhood Hits	149
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

BAZ2A_MOUSE
θ value	0.21417 (rank : 360)	NC score	0.081063 (rank : 460)
Query Neighborhood Hits	872	Target Neighborhood Hits	744	Shared Neighborhood Hits	191
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

CEP68_HUMAN
θ value	0.21417 (rank : 361)	NC score	0.048350 (rank : 789)
Query Neighborhood Hits	872	Target Neighborhood Hits	128	Shared Neighborhood Hits	40
SwissProt Accessions	Q76N32, O60326, Q9BQ18, Q9UDM9	Gene names	CEP68, KIAA0582
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 68 kDa (Cep68 protein).

CITE4_MOUSE
θ value	0.21417 (rank : 362)	NC score	0.057163 (rank : 678)
Query Neighborhood Hits	872	Target Neighborhood Hits	73	Shared Neighborhood Hits	23
SwissProt Accessions	Q9WUL8, Q66JX0, Q8R176, Q9CZV4	Gene names	Cited4, Mrg2
Domain Architecture	No domain graphic available
Description	Cbp/p300-interacting transactivator 4 (MSG1-related protein 2) (MRG- 2).

GFC1_HUMAN
θ value	0.21417 (rank : 363)	NC score	0.041317 (rank : 824)
Query Neighborhood Hits	872	Target Neighborhood Hits	95	Shared Neighborhood Hits	39
SwissProt Accessions	P63117	Gene names
Domain Architecture	No domain graphic available
Description	HERV-F(c)1_Xq21.33 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein].

GLIS3_HUMAN
θ value	0.21417 (rank : 364)	NC score	0.000807 (rank : 1115)
Query Neighborhood Hits	872	Target Neighborhood Hits	758	Shared Neighborhood Hits	52
SwissProt Accessions	Q8NEA6	Gene names	GLIS3, ZNF515
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS3 (GLI-similar 3) (Zinc finger protein 515).

GNAS1_MOUSE
θ value	0.21417 (rank : 365)	NC score	0.108024 (rank : 311)
Query Neighborhood Hits	872	Target Neighborhood Hits	651	Shared Neighborhood Hits	272
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

K1949_HUMAN
θ value	0.21417 (rank : 366)	NC score	0.040598 (rank : 828)
Query Neighborhood Hits	872	Target Neighborhood Hits	121	Shared Neighborhood Hits	24
SwissProt Accessions	Q6NYC8, Q68CK8, Q6ZUJ6, Q8NDQ4, Q8TF52, Q9BRL9	Gene names	KIAA1949
Domain Architecture	No domain graphic available
Description	Protein KIAA1949.

NOXO1_HUMAN
θ value	0.21417 (rank : 367)	NC score	0.115022 (rank : 284)
Query Neighborhood Hits	872	Target Neighborhood Hits	100	Shared Neighborhood Hits	66
SwissProt Accessions	Q8NFA2, Q86YM1, Q8NFA3, Q96B73	Gene names	NOXO1, P41NOX
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Nox-organizing protein 1) (NADPH oxidase regulatory protein).

SYNJ1_HUMAN
θ value	0.21417 (rank : 368)	NC score	0.093962 (rank : 364)
Query Neighborhood Hits	872	Target Neighborhood Hits	498	Shared Neighborhood Hits	170
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

SYP2L_HUMAN
θ value	0.21417 (rank : 369)	NC score	0.071676 (rank : 531)
Query Neighborhood Hits	872	Target Neighborhood Hits	400	Shared Neighborhood Hits	133
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

ACRO_HUMAN
θ value	0.279714 (rank : 370)	NC score	0.002567 (rank : 1109)
Query Neighborhood Hits	872	Target Neighborhood Hits	291	Shared Neighborhood Hits	46
SwissProt Accessions	P10323, Q6ICK2	Gene names	ACR, ACRS
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

BIN1_MOUSE
θ value	0.279714 (rank : 371)	NC score	0.078965 (rank : 479)
Query Neighborhood Hits	872	Target Neighborhood Hits	283	Shared Neighborhood Hits	115
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

BRD4_HUMAN
θ value	0.279714 (rank : 372)	NC score	0.067254 (rank : 568)
Query Neighborhood Hits	872	Target Neighborhood Hits	851	Shared Neighborhood Hits	160
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

CJ047_HUMAN
θ value	0.279714 (rank : 373)	NC score	0.066282 (rank : 576)
Query Neighborhood Hits	872	Target Neighborhood Hits	164	Shared Neighborhood Hits	67
SwissProt Accessions	Q86WR7, Q5W0J9, Q5W0K0, Q5W0K1, Q5W0K2, Q6PJC8, Q8N317	Gene names	C10orf47
Domain Architecture	No domain graphic available
Description	Protein C10orf47.

COFA1_HUMAN
θ value	0.279714 (rank : 374)	NC score	0.074272 (rank : 512)
Query Neighborhood Hits	872	Target Neighborhood Hits	292	Shared Neighborhood Hits	98
SwissProt Accessions	P39059, Q5T6J4, Q9Y4W4	Gene names	COL15A1
Domain Architecture
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV) (Restin) (Related to endostatin)].

CSPG5_MOUSE
θ value	0.279714 (rank : 375)	NC score	0.077471 (rank : 489)
Query Neighborhood Hits	872	Target Neighborhood Hits	211	Shared Neighborhood Hits	75
SwissProt Accessions	Q71M36, Q71M37, Q7TNT8, Q8BPJ5, Q9QY32	Gene names	Cspg5, Caleb, Ngc
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

DBP_HUMAN
θ value	0.279714 (rank : 376)	NC score	0.031989 (rank : 882)
Query Neighborhood Hits	872	Target Neighborhood Hits	136	Shared Neighborhood Hits	36
SwissProt Accessions	Q10586	Gene names	DBP
Domain Architecture
Description	D site-binding protein (Albumin D box-binding protein) (Albumin D- element-binding protein) (TAXREB302).

FBN1_HUMAN
θ value	0.279714 (rank : 377)	NC score	0.012758 (rank : 1028)
Query Neighborhood Hits	872	Target Neighborhood Hits	557	Shared Neighborhood Hits	28
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FIP1_MOUSE
θ value	0.279714 (rank : 378)	NC score	0.047701 (rank : 790)
Query Neighborhood Hits	872	Target Neighborhood Hits	120	Shared Neighborhood Hits	32
SwissProt Accessions	Q9D824, Q8BWX7, Q99LH0, Q9DBB2	Gene names	Fip1l1
Domain Architecture	No domain graphic available
Description	Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1).

HXA3_MOUSE
θ value	0.279714 (rank : 379)	NC score	0.029634 (rank : 893)
Query Neighborhood Hits	872	Target Neighborhood Hits	558	Shared Neighborhood Hits	111
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

NBL1_MOUSE
θ value	0.279714 (rank : 380)	NC score	0.040389 (rank : 829)
Query Neighborhood Hits	872	Target Neighborhood Hits	21	Shared Neighborhood Hits	5
SwissProt Accessions	Q61477	Gene names	Nbl1, Dan, Dana
Domain Architecture
Description	Neuroblastoma suppressor of tumorigenicity 1 precursor (Zinc finger protein DAN) (N03).

OBSCN_HUMAN
θ value	0.279714 (rank : 381)	NC score	0.025035 (rank : 930)
Query Neighborhood Hits	872	Target Neighborhood Hits	1931	Shared Neighborhood Hits	262
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

RNC_HUMAN
θ value	0.279714 (rank : 382)	NC score	0.054957 (rank : 710)
Query Neighborhood Hits	872	Target Neighborhood Hits	176	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NRR4, Q7Z5V2, Q86YH0, Q9NW73, Q9Y2V9, Q9Y4Y0	Gene names	RNASEN, RN3, RNASE3L
Domain Architecture
Description	Ribonuclease III (EC 3.1.26.3) (RNase III) (Drosha) (p241).

RNF38_HUMAN
θ value	0.279714 (rank : 383)	NC score	0.022788 (rank : 948)
Query Neighborhood Hits	872	Target Neighborhood Hits	155	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H0F5, Q8N0Y0	Gene names	RNF38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

SMCA2_HUMAN
θ value	0.279714 (rank : 384)	NC score	0.032615 (rank : 877)
Query Neighborhood Hits	872	Target Neighborhood Hits	503	Shared Neighborhood Hits	96
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

VAV3_HUMAN
θ value	0.279714 (rank : 385)	NC score	0.176132 (rank : 140)
Query Neighborhood Hits	872	Target Neighborhood Hits	398	Shared Neighborhood Hits	135
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

WASF3_MOUSE
θ value	0.279714 (rank : 386)	NC score	0.108341 (rank : 308)
Query Neighborhood Hits	872	Target Neighborhood Hits	188	Shared Neighborhood Hits	71
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

ZN263_HUMAN
θ value	0.279714 (rank : 387)	NC score	-0.004742 (rank : 1138)
Query Neighborhood Hits	872	Target Neighborhood Hits	795	Shared Neighborhood Hits	52
SwissProt Accessions	O14978, O43387, Q96H95	Gene names	ZNF263, FPM315
Domain Architecture
Description	Zinc finger protein 263 (Zinc finger protein FPM315).

AHI1_MOUSE
θ value	0.365318 (rank : 388)	NC score	0.132385 (rank : 235)
Query Neighborhood Hits	872	Target Neighborhood Hits	496	Shared Neighborhood Hits	137
SwissProt Accessions	Q8K3E5, Q7TNV2, Q9CVY1	Gene names	Ahi1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein) (AHI-1).

CBP_HUMAN
θ value	0.365318 (rank : 389)	NC score	0.134992 (rank : 228)
Query Neighborhood Hits	872	Target Neighborhood Hits	941	Shared Neighborhood Hits	294
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

EPN3_MOUSE
θ value	0.365318 (rank : 390)	NC score	0.108142 (rank : 310)
Query Neighborhood Hits	872	Target Neighborhood Hits	312	Shared Neighborhood Hits	141
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

FUBP3_HUMAN
θ value	0.365318 (rank : 391)	NC score	0.022963 (rank : 944)
Query Neighborhood Hits	872	Target Neighborhood Hits	68	Shared Neighborhood Hits	18
SwissProt Accessions	Q96I24, Q92946, Q9BVB6	Gene names	FUBP3
Domain Architecture
Description	Far upstream element-binding protein 3 (FUSE-binding protein 3).

KCNH2_MOUSE
θ value	0.365318 (rank : 392)	NC score	0.021532 (rank : 962)
Query Neighborhood Hits	872	Target Neighborhood Hits	165	Shared Neighborhood Hits	33
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

MNT_MOUSE
θ value	0.365318 (rank : 393)	NC score	0.074870 (rank : 509)
Query Neighborhood Hits	872	Target Neighborhood Hits	432	Shared Neighborhood Hits	114
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

P85B_HUMAN
θ value	0.365318 (rank : 394)	NC score	0.138192 (rank : 217)
Query Neighborhood Hits	872	Target Neighborhood Hits	543	Shared Neighborhood Hits	92
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

PRR13_MOUSE
θ value	0.365318 (rank : 395)	NC score	0.090826 (rank : 389)
Query Neighborhood Hits	872	Target Neighborhood Hits	54	Shared Neighborhood Hits	28
SwissProt Accessions	Q9CQJ5, Q3U3U4	Gene names	Prr13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

RUSC2_HUMAN
θ value	0.365318 (rank : 396)	NC score	0.080581 (rank : 463)
Query Neighborhood Hits	872	Target Neighborhood Hits	205	Shared Neighborhood Hits	86
SwissProt Accessions	Q8N2Y8, O15080, Q6P1W7	Gene names	RUSC2, KIAA0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

TARA_MOUSE
θ value	0.365318 (rank : 397)	NC score	0.071262 (rank : 534)
Query Neighborhood Hits	872	Target Neighborhood Hits	1133	Shared Neighborhood Hits	167
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

ZBT45_HUMAN
θ value	0.365318 (rank : 398)	NC score	0.002062 (rank : 1112)
Query Neighborhood Hits	872	Target Neighborhood Hits	901	Shared Neighborhood Hits	94
SwissProt Accessions	Q96K62	Gene names	ZBTB45, ZNF499
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 45 (Zinc finger protein 499).

ZBTB4_HUMAN
θ value	0.365318 (rank : 399)	NC score	0.005859 (rank : 1089)
Query Neighborhood Hits	872	Target Neighborhood Hits	926	Shared Neighborhood Hits	77
SwissProt Accessions	Q9P1Z0, Q7Z697, Q86XJ4, Q8N4V8	Gene names	ZBTB4, KIAA1538
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 4 (KAISO-like zinc finger protein 1) (KAISO-L1).

AHI1_HUMAN
θ value	0.47712 (rank : 400)	NC score	0.135372 (rank : 227)
Query Neighborhood Hits	872	Target Neighborhood Hits	537	Shared Neighborhood Hits	137
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

BC11A_HUMAN
θ value	0.47712 (rank : 401)	NC score	0.004864 (rank : 1096)
Query Neighborhood Hits	872	Target Neighborhood Hits	745	Shared Neighborhood Hits	40
SwissProt Accessions	Q9H165, Q86W14, Q8WU92, Q96JL6, Q9H163, Q9H164, Q9H3G9, Q9NWA7	Gene names	BCL11A, CTIP1, EVI9, KIAA1809
Domain Architecture	No domain graphic available
Description	B-cell lymphoma/leukemia 11A (B-cell CLL/lymphoma 11A) (COUP-TF- interacting protein 1) (Ecotropic viral integration site 9 protein) (EVI-9).

BC11A_MOUSE
θ value	0.47712 (rank : 402)	NC score	0.006221 (rank : 1081)
Query Neighborhood Hits	872	Target Neighborhood Hits	732	Shared Neighborhood Hits	38
SwissProt Accessions	Q9QYE3, Q80T89, Q8BLC7, Q8BLR4, Q8BWX3, Q921V4, Q9D0V2, Q9JIT4, Q9JLK8, Q9JLK9	Gene names	Bcl11a, Ctip1, Evi9, Kiaa1809
Domain Architecture	No domain graphic available
Description	B-cell lymphoma/leukemia 11A (B-cell CLL/lymphoma 11A) (COUP-TF- interacting protein 1) (Ecotropic viral integration site 9 protein) (EVI-9).

CO8A2_MOUSE
θ value	0.47712 (rank : 403)	NC score	0.079195 (rank : 478)
Query Neighborhood Hits	872	Target Neighborhood Hits	273	Shared Neighborhood Hits	116
SwissProt Accessions	P25318, Q68ED0, Q6KAQ4, Q6P1C4	Gene names	Col8a2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(VIII) chain precursor (Endothelial collagen).

DIDO1_HUMAN
θ value	0.47712 (rank : 404)	NC score	0.170653 (rank : 148)
Query Neighborhood Hits	872	Target Neighborhood Hits	960	Shared Neighborhood Hits	295
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

EMIL2_HUMAN
θ value	0.47712 (rank : 405)	NC score	0.042657 (rank : 817)
Query Neighborhood Hits	872	Target Neighborhood Hits	573	Shared Neighborhood Hits	105
SwissProt Accessions	Q9BXX0, Q8NBH3, Q96JQ4	Gene names	EMILIN2
Domain Architecture
Description	EMILIN-2 precursor (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Protein FOAP-10).

ENAH_HUMAN
θ value	0.47712 (rank : 406)	NC score	0.063967 (rank : 599)
Query Neighborhood Hits	872	Target Neighborhood Hits	784	Shared Neighborhood Hits	130
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

ERBB2_HUMAN
θ value	0.47712 (rank : 407)	NC score	0.006679 (rank : 1080)
Query Neighborhood Hits	872	Target Neighborhood Hits	1073	Shared Neighborhood Hits	129
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

FIZ1_HUMAN
θ value	0.47712 (rank : 408)	NC score	-0.004677 (rank : 1137)
Query Neighborhood Hits	872	Target Neighborhood Hits	715	Shared Neighborhood Hits	38
SwissProt Accessions	Q96SL8, Q6ZMJ7	Gene names	FIZ1
Domain Architecture	No domain graphic available
Description	Flt3-interacting zinc finger protein 1.

FMN1A_MOUSE
θ value	0.47712 (rank : 409)	NC score	0.093540 (rank : 369)
Query Neighborhood Hits	872	Target Neighborhood Hits	423	Shared Neighborhood Hits	128
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

FMN1B_MOUSE
θ value	0.47712 (rank : 410)	NC score	0.093343 (rank : 370)
Query Neighborhood Hits	872	Target Neighborhood Hits	447	Shared Neighborhood Hits	124
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

FOXN1_HUMAN
θ value	0.47712 (rank : 411)	NC score	0.070094 (rank : 543)
Query Neighborhood Hits	872	Target Neighborhood Hits	377	Shared Neighborhood Hits	182
SwissProt Accessions	O15353, O15352	Gene names	FOXN1, WHN
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude).

IRS2_MOUSE
θ value	0.47712 (rank : 412)	NC score	0.062653 (rank : 610)
Query Neighborhood Hits	872	Target Neighborhood Hits	248	Shared Neighborhood Hits	84
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

IRX5_MOUSE
θ value	0.47712 (rank : 413)	NC score	0.032655 (rank : 876)
Query Neighborhood Hits	872	Target Neighborhood Hits	324	Shared Neighborhood Hits	61
SwissProt Accessions	Q9JKQ4, Q80WV4, Q9JLL5	Gene names	Irx5, Irxb2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-5 (Iroquois homeobox protein 5) (Homeodomain protein IRXB2).

LOXL1_MOUSE
θ value	0.47712 (rank : 414)	NC score	0.025531 (rank : 927)
Query Neighborhood Hits	872	Target Neighborhood Hits	58	Shared Neighborhood Hits	28
SwissProt Accessions	P97873, Q91ZY4, Q99KX3	Gene names	Loxl1, Lox2, Loxl
Domain Architecture
Description	Lysyl oxidase homolog 1 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 1) (Lysyl oxidase 2).

MUC2_HUMAN
θ value	0.47712 (rank : 415)	NC score	0.060845 (rank : 630)
Query Neighborhood Hits	872	Target Neighborhood Hits	906	Shared Neighborhood Hits	154
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

PDCD7_MOUSE
θ value	0.47712 (rank : 416)	NC score	0.058557 (rank : 664)
Query Neighborhood Hits	872	Target Neighborhood Hits	214	Shared Neighborhood Hits	44
SwissProt Accessions	Q9WTY1, Q8R5D9	Gene names	Pdcd7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18).

PEF1_HUMAN
θ value	0.47712 (rank : 417)	NC score	0.022279 (rank : 952)
Query Neighborhood Hits	872	Target Neighborhood Hits	135	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UBV8	Gene names	PEF1, ABP32
Domain Architecture	No domain graphic available
Description	Peflin (PEF protein with a long N-terminal hydrophobic domain) (Penta- EF hand domain-containing protein 1).

PELP1_MOUSE
θ value	0.47712 (rank : 418)	NC score	0.142595 (rank : 208)
Query Neighborhood Hits	872	Target Neighborhood Hits	709	Shared Neighborhood Hits	248
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

REXO1_MOUSE
θ value	0.47712 (rank : 419)	NC score	0.047370 (rank : 792)
Query Neighborhood Hits	872	Target Neighborhood Hits	166	Shared Neighborhood Hits	44
SwissProt Accessions	Q7TT28, Q3UMP1, Q69ZR0, Q6NSQ6, Q6PI95, Q9DA29	Gene names	Rexo1, Kiaa1138, Tceb3bp1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Transcription elongation factor B polypeptide 3-binding protein 1).

SET1A_HUMAN
θ value	0.47712 (rank : 420)	NC score	0.080015 (rank : 469)
Query Neighborhood Hits	872	Target Neighborhood Hits	690	Shared Neighborhood Hits	144
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SH3G2_MOUSE
θ value	0.47712 (rank : 421)	NC score	0.169524 (rank : 150)
Query Neighborhood Hits	872	Target Neighborhood Hits	319	Shared Neighborhood Hits	130
SwissProt Accessions	Q62420	Gene names	Sh3gl2, Sh3d2a
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (SH3p4).

SP7_MOUSE
θ value	0.47712 (rank : 422)	NC score	0.008851 (rank : 1064)
Query Neighborhood Hits	872	Target Neighborhood Hits	756	Shared Neighborhood Hits	77
SwissProt Accessions	Q8VI67, Q8C5R3, Q8C6A7	Gene names	Sp7, Osx
Domain Architecture	No domain graphic available
Description	Transcription factor Sp7 (Zinc finger protein osterix) (C22).

TTP_MOUSE
θ value	0.47712 (rank : 423)	NC score	0.025668 (rank : 924)
Query Neighborhood Hits	872	Target Neighborhood Hits	75	Shared Neighborhood Hits	11
SwissProt Accessions	P22893, P11520	Gene names	Zfp36, Tis11, Tis11a
Domain Architecture
Description	Tristetraproline (TTP) (Zinc finger protein 36) (Zfp-36) (TIS11A protein) (TIS11) (Growth factor-inducible nuclear protein NUP475) (TPA-induced sequence 11).

VAV3_MOUSE
θ value	0.47712 (rank : 424)	NC score	0.174417 (rank : 143)
Query Neighborhood Hits	872	Target Neighborhood Hits	404	Shared Neighborhood Hits	137
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

ZN341_HUMAN
θ value	0.47712 (rank : 425)	NC score	-0.002660 (rank : 1128)
Query Neighborhood Hits	872	Target Neighborhood Hits	803	Shared Neighborhood Hits	78
SwissProt Accessions	Q9BYN7, Q5JXM8, Q96ST5	Gene names	ZNF341
Domain Architecture	No domain graphic available
Description	Zinc finger protein 341.

ATBF1_HUMAN
θ value	0.62314 (rank : 426)	NC score	0.024660 (rank : 933)
Query Neighborhood Hits	872	Target Neighborhood Hits	1547	Shared Neighborhood Hits	154
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

CO3A1_HUMAN
θ value	0.62314 (rank : 427)	NC score	0.093822 (rank : 367)
Query Neighborhood Hits	872	Target Neighborhood Hits	452	Shared Neighborhood Hits	150
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CO3A1_MOUSE
θ value	0.62314 (rank : 428)	NC score	0.096612 (rank : 352)
Query Neighborhood Hits	872	Target Neighborhood Hits	466	Shared Neighborhood Hits	151
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

COAA1_MOUSE
θ value	0.62314 (rank : 429)	NC score	0.079333 (rank : 476)
Query Neighborhood Hits	872	Target Neighborhood Hits	286	Shared Neighborhood Hits	107
SwissProt Accessions	Q05306	Gene names	Col10a1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

DAAM1_HUMAN
θ value	0.62314 (rank : 430)	NC score	0.058237 (rank : 669)
Query Neighborhood Hits	872	Target Neighborhood Hits	483	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y4D1, Q86U34, Q8N1Z8, Q8TB39	Gene names	DAAM1, KIAA0666
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

DVL1L_HUMAN
θ value	0.62314 (rank : 431)	NC score	0.029120 (rank : 897)
Query Neighborhood Hits	872	Target Neighborhood Hits	146	Shared Neighborhood Hits	17
SwissProt Accessions	P54792	Gene names	DVL1L1, DVL, DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled- 1-like) (DSH homolog 1-like).

EP300_HUMAN
θ value	0.62314 (rank : 432)	NC score	0.120039 (rank : 261)
Query Neighborhood Hits	872	Target Neighborhood Hits	821	Shared Neighborhood Hits	254
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

HXA10_MOUSE
θ value	0.62314 (rank : 433)	NC score	0.014982 (rank : 1002)
Query Neighborhood Hits	872	Target Neighborhood Hits	365	Shared Neighborhood Hits	50
SwissProt Accessions	P31310, Q80Y22	Gene names	Hoxa10, Hox-1.8, Hoxa-10
Domain Architecture
Description	Homeobox protein Hox-A10 (Hox-1.8).

IL3B2_MOUSE
θ value	0.62314 (rank : 434)	NC score	0.102770 (rank : 328)
Query Neighborhood Hits	872	Target Neighborhood Hits	372	Shared Neighborhood Hits	191
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

IRS1_MOUSE
θ value	0.62314 (rank : 435)	NC score	0.039407 (rank : 835)
Query Neighborhood Hits	872	Target Neighborhood Hits	112	Shared Neighborhood Hits	30
SwissProt Accessions	P35569	Gene names	Irs1, Irs-1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

K0460_MOUSE
θ value	0.62314 (rank : 436)	NC score	0.038135 (rank : 844)
Query Neighborhood Hits	872	Target Neighborhood Hits	374	Shared Neighborhood Hits	81
SwissProt Accessions	Q6NXI6, Q3U3L8, Q6ZQA7	Gene names	Kiaa0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

KCNN2_MOUSE
θ value	0.62314 (rank : 437)	NC score	0.008517 (rank : 1070)
Query Neighborhood Hits	872	Target Neighborhood Hits	120	Shared Neighborhood Hits	4
SwissProt Accessions	P58390	Gene names	Kcnn2, Sk2
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 2 (SK2).

LPP_MOUSE
θ value	0.62314 (rank : 438)	NC score	0.031660 (rank : 886)
Query Neighborhood Hits	872	Target Neighborhood Hits	247	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BFW7, Q5U407, Q8BHI1, Q8BKI0, Q8BKN2, Q8BLF4, Q8BLG3, Q8C101	Gene names	Lpp
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner homolog.

MEF2C_HUMAN
θ value	0.62314 (rank : 439)	NC score	0.031677 (rank : 885)
Query Neighborhood Hits	872	Target Neighborhood Hits	90	Shared Neighborhood Hits	31
SwissProt Accessions	Q06413	Gene names	MEF2C
Domain Architecture
Description	Myocyte-specific enhancer factor 2C.

MK07_MOUSE
θ value	0.62314 (rank : 440)	NC score	0.005954 (rank : 1088)
Query Neighborhood Hits	872	Target Neighborhood Hits	1054	Shared Neighborhood Hits	119
SwissProt Accessions	Q9WVS8	Gene names	Mapk7, Erk5
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase).

NANO1_HUMAN
θ value	0.62314 (rank : 441)	NC score	0.023753 (rank : 940)
Query Neighborhood Hits	872	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WY41	Gene names	NANOS1, NOS1
Domain Architecture
Description	Nanos homolog 1 (NOS-1) (EC_Rep1a).

OGFR_HUMAN
θ value	0.62314 (rank : 442)	NC score	0.268964 (rank : 65)
Query Neighborhood Hits	872	Target Neighborhood Hits	1582	Shared Neighborhood Hits	496
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

PEX14_MOUSE
θ value	0.62314 (rank : 443)	NC score	0.037603 (rank : 846)
Query Neighborhood Hits	872	Target Neighborhood Hits	62	Shared Neighborhood Hits	16
SwissProt Accessions	Q9R0A0	Gene names	Pex14
Domain Architecture
Description	Peroxisomal membrane protein PEX14 (Peroxin-14) (Peroxisomal membrane anchor protein PEX14) (PTS1 receptor docking protein).

PP1RA_HUMAN
θ value	0.62314 (rank : 444)	NC score	0.065856 (rank : 578)
Query Neighborhood Hits	872	Target Neighborhood Hits	180	Shared Neighborhood Hits	74
SwissProt Accessions	Q96QC0, O00405	Gene names	PPP1R10, CAT53, FB19, PNUTS
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 1 regulatory subunit 10 (Phosphatase 1 nuclear targeting subunit) (MHC class I region proline- rich protein CAT53) (FB19 protein) (PP1-binding protein of 114 kDa) (p99).

RX_MOUSE
θ value	0.62314 (rank : 445)	NC score	0.021772 (rank : 958)
Query Neighborhood Hits	872	Target Neighborhood Hits	429	Shared Neighborhood Hits	62
SwissProt Accessions	O35602, O08748	Gene names	Rax, Rx
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

SEN54_HUMAN
θ value	0.62314 (rank : 446)	NC score	0.026634 (rank : 918)
Query Neighborhood Hits	872	Target Neighborhood Hits	23	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z6J9, Q86WV3, Q86XE4, Q8N9H2	Gene names	TSEN54, SEN54
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen54 (tRNA-intron endonuclease Sen54) (HsSen54).

UBQL3_HUMAN
θ value	0.62314 (rank : 447)	NC score	0.039722 (rank : 834)
Query Neighborhood Hits	872	Target Neighborhood Hits	141	Shared Neighborhood Hits	64
SwissProt Accessions	Q9H347, Q9NRE0	Gene names	UBQLN3
Domain Architecture
Description	Ubiquilin-3.

ZN408_HUMAN
θ value	0.62314 (rank : 448)	NC score	-0.006055 (rank : 1141)
Query Neighborhood Hits	872	Target Neighborhood Hits	775	Shared Neighborhood Hits	38
SwissProt Accessions	Q9H9D4	Gene names	ZNF408, PFM14, PRDM17
Domain Architecture	No domain graphic available
Description	Zinc finger protein 408 (PR-domain zinc finger protein 17).

BC11B_MOUSE
θ value	0.813845 (rank : 449)	NC score	0.004722 (rank : 1099)
Query Neighborhood Hits	872	Target Neighborhood Hits	767	Shared Neighborhood Hits	50
SwissProt Accessions	Q99PV8, Q8C2I1, Q99PV6, Q99PV7, Q9JLF8	Gene names	Bcl11b, Ctip2, Rit1
Domain Architecture	No domain graphic available
Description	B-cell lymphoma/leukemia 11B (B-cell CLL/lymphoma 11B) (Radiation- induced tumor suppressor gene 1 protein) (mRit1) (COUP-TF-interacting protein 2).

BRD4_MOUSE
θ value	0.813845 (rank : 450)	NC score	0.068754 (rank : 555)
Query Neighborhood Hits	872	Target Neighborhood Hits	845	Shared Neighborhood Hits	155
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

CAC1G_HUMAN
θ value	0.813845 (rank : 451)	NC score	0.074779 (rank : 510)
Query Neighborhood Hits	872	Target Neighborhood Hits	587	Shared Neighborhood Hits	225
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

CO1A2_HUMAN
θ value	0.813845 (rank : 452)	NC score	0.080808 (rank : 462)
Query Neighborhood Hits	872	Target Neighborhood Hits	329	Shared Neighborhood Hits	118
SwissProt Accessions	P08123, P02464, Q9UEB6, Q9UPH0	Gene names	COL1A2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

CO4A4_HUMAN
θ value	0.813845 (rank : 453)	NC score	0.098348 (rank : 339)
Query Neighborhood Hits	872	Target Neighborhood Hits	440	Shared Neighborhood Hits	166
SwissProt Accessions	P53420	Gene names	COL4A4
Domain Architecture
Description	Collagen alpha-4(IV) chain precursor.

CO9A1_MOUSE
θ value	0.813845 (rank : 454)	NC score	0.099027 (rank : 335)
Query Neighborhood Hits	872	Target Neighborhood Hits	477	Shared Neighborhood Hits	174
SwissProt Accessions	Q05722, Q61269, Q61270, Q61433, Q61940	Gene names	Col9a1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

COHA1_MOUSE
θ value	0.813845 (rank : 455)	NC score	0.085805 (rank : 428)
Query Neighborhood Hits	872	Target Neighborhood Hits	414	Shared Neighborhood Hits	141
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

CRTC1_HUMAN
θ value	0.813845 (rank : 456)	NC score	0.090587 (rank : 391)
Query Neighborhood Hits	872	Target Neighborhood Hits	319	Shared Neighborhood Hits	135
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

FBN1_MOUSE
θ value	0.813845 (rank : 457)	NC score	0.012241 (rank : 1036)
Query Neighborhood Hits	872	Target Neighborhood Hits	563	Shared Neighborhood Hits	32
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

GR65_HUMAN
θ value	0.813845 (rank : 458)	NC score	0.045913 (rank : 800)
Query Neighborhood Hits	872	Target Neighborhood Hits	148	Shared Neighborhood Hits	71
SwissProt Accessions	Q9BQQ3, Q8N272, Q96H42	Gene names	GORASP1, GRASP65
Domain Architecture	No domain graphic available
Description	Golgi reassembly-stacking protein 1 (Golgi reassembly-stacking protein of 65 kDa) (GRASP65) (Golgi peripheral membrane protein p65) (Golgi phosphoprotein 5) (GOLPH5).

IER5_MOUSE
θ value	0.813845 (rank : 459)	NC score	0.046295 (rank : 798)
Query Neighborhood Hits	872	Target Neighborhood Hits	110	Shared Neighborhood Hits	35
SwissProt Accessions	O89113, Q8CGI0	Gene names	Ier5
Domain Architecture	No domain graphic available
Description	Immediate early response gene 5 protein.

IL3RB_MOUSE
θ value	0.813845 (rank : 460)	NC score	0.097583 (rank : 345)
Query Neighborhood Hits	872	Target Neighborhood Hits	355	Shared Neighborhood Hits	179
SwissProt Accessions	P26955	Gene names	Csf2rb, Aic2b, Csf2rb1, Il3rb1
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen).

K1802_HUMAN
θ value	0.813845 (rank : 461)	NC score	0.102995 (rank : 327)
Query Neighborhood Hits	872	Target Neighborhood Hits	1378	Shared Neighborhood Hits	293
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

KI13B_HUMAN
θ value	0.813845 (rank : 462)	NC score	0.008811 (rank : 1066)
Query Neighborhood Hits	872	Target Neighborhood Hits	492	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NQT8, O75134, Q9BYJ6	Gene names	KIF13B, GAKIN, KIAA0639
Domain Architecture
Description	Kinesin-like protein KIF13B (Kinesin-like protein GAKIN).

LRC56_HUMAN
θ value	0.813845 (rank : 463)	NC score	0.028265 (rank : 908)
Query Neighborhood Hits	872	Target Neighborhood Hits	165	Shared Neighborhood Hits	36
SwissProt Accessions	Q8IYG6, Q8N3Q4	Gene names	LRRC56
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 56.

MEF2B_MOUSE
θ value	0.813845 (rank : 464)	NC score	0.093110 (rank : 372)
Query Neighborhood Hits	872	Target Neighborhood Hits	218	Shared Neighborhood Hits	125
SwissProt Accessions	O55087, O55088, O55089, O55090, O55231, Q61843	Gene names	Mef2b
Domain Architecture
Description	Myocyte-specific enhancer factor 2B.

NCF2_HUMAN
θ value	0.813845 (rank : 465)	NC score	0.212084 (rank : 94)
Query Neighborhood Hits	872	Target Neighborhood Hits	229	Shared Neighborhood Hits	124
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

NECD_HUMAN
θ value	0.813845 (rank : 466)	NC score	0.010894 (rank : 1050)
Query Neighborhood Hits	872	Target Neighborhood Hits	82	Shared Neighborhood Hits	19
SwissProt Accessions	Q99608	Gene names	NDN
Domain Architecture
Description	Necdin.

PACN2_HUMAN
θ value	0.813845 (rank : 467)	NC score	0.152164 (rank : 189)
Query Neighborhood Hits	872	Target Neighborhood Hits	339	Shared Neighborhood Hits	125
SwissProt Accessions	Q9UNF0, O95921, Q96HV9, Q9H0D3, Q9NPN1, Q9Y4V2	Gene names	PACSIN2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

PACN2_MOUSE
θ value	0.813845 (rank : 468)	NC score	0.149806 (rank : 195)
Query Neighborhood Hits	872	Target Neighborhood Hits	382	Shared Neighborhood Hits	133
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

PACN3_MOUSE
θ value	0.813845 (rank : 469)	NC score	0.140178 (rank : 213)
Query Neighborhood Hits	872	Target Neighborhood Hits	380	Shared Neighborhood Hits	122
SwissProt Accessions	Q99JB8, Q9EQP9	Gene names	Pacsin3
Domain Architecture
Description	Protein kinase C and casein kinase II substrate protein 3.

PI5PA_HUMAN
θ value	0.813845 (rank : 470)	NC score	0.182200 (rank : 132)
Query Neighborhood Hits	872	Target Neighborhood Hits	749	Shared Neighborhood Hits	333
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

RGS3_HUMAN
θ value	0.813845 (rank : 471)	NC score	0.168394 (rank : 155)
Query Neighborhood Hits	872	Target Neighborhood Hits	1375	Shared Neighborhood Hits	422
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

RIN3_HUMAN
θ value	0.813845 (rank : 472)	NC score	0.045936 (rank : 799)
Query Neighborhood Hits	872	Target Neighborhood Hits	227	Shared Neighborhood Hits	74
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

RNF38_MOUSE
θ value	0.813845 (rank : 473)	NC score	0.020170 (rank : 974)
Query Neighborhood Hits	872	Target Neighborhood Hits	153	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BI21, Q6P5B1	Gene names	Rnf38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

RP3A_HUMAN
θ value	0.813845 (rank : 474)	NC score	0.032613 (rank : 878)
Query Neighborhood Hits	872	Target Neighborhood Hits	305	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SEM6C_MOUSE
θ value	0.813845 (rank : 475)	NC score	0.055006 (rank : 708)
Query Neighborhood Hits	872	Target Neighborhood Hits	352	Shared Neighborhood Hits	189
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

SIX5_HUMAN
θ value	0.813845 (rank : 476)	NC score	0.025407 (rank : 928)
Query Neighborhood Hits	872	Target Neighborhood Hits	386	Shared Neighborhood Hits	63
SwissProt Accessions	Q8N196	Gene names	SIX5, DMAHP
Domain Architecture	No domain graphic available
Description	Homeobox protein SIX5 (DM locus-associated homeodomain protein).

SMAD5_MOUSE
θ value	0.813845 (rank : 477)	NC score	0.009330 (rank : 1060)
Query Neighborhood Hits	872	Target Neighborhood Hits	74	Shared Neighborhood Hits	19
SwissProt Accessions	P97454, P70341, Q810K0	Gene names	Smad5, Madh5, Msmad5
Domain Architecture
Description	Mothers against decapentaplegic homolog 5 (SMAD 5) (Mothers against DPP homolog 5) (Smad5) (mSmad5) (Dwarfin-C) (Dwf-C).

SRBP1_HUMAN
θ value	0.813845 (rank : 478)	NC score	0.054127 (rank : 728)
Query Neighborhood Hits	872	Target Neighborhood Hits	225	Shared Neighborhood Hits	65
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

SYNPO_MOUSE
θ value	0.813845 (rank : 479)	NC score	0.069573 (rank : 545)
Query Neighborhood Hits	872	Target Neighborhood Hits	242	Shared Neighborhood Hits	84
SwissProt Accessions	Q8CC35, Q99JI0	Gene names	Synpo, Kiaa1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

TIAM1_HUMAN
θ value	0.813845 (rank : 480)	NC score	0.095593 (rank : 357)
Query Neighborhood Hits	872	Target Neighborhood Hits	225	Shared Neighborhood Hits	48
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

TLE1_MOUSE
θ value	0.813845 (rank : 481)	NC score	0.044230 (rank : 806)
Query Neighborhood Hits	872	Target Neighborhood Hits	491	Shared Neighborhood Hits	147
SwissProt Accessions	Q62440	Gene names	Tle1, Grg1
Domain Architecture
Description	Transducin-like enhancer protein 1 (Groucho-related protein 1) (Grg- 1).

ZN409_HUMAN
θ value	0.813845 (rank : 482)	NC score	0.061024 (rank : 627)
Query Neighborhood Hits	872	Target Neighborhood Hits	842	Shared Neighborhood Hits	148
SwissProt Accessions	Q9UPU6	Gene names	ZNF409, KIAA1056
Domain Architecture	No domain graphic available
Description	Zinc finger protein 409.

AKA11_HUMAN
θ value	1.06291 (rank : 483)	NC score	0.025141 (rank : 929)
Query Neighborhood Hits	872	Target Neighborhood Hits	57	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UKA4, O75124, Q9NUK7	Gene names	AKAP11, AKAP220, KIAA0629
Domain Architecture
Description	A-kinase anchor protein 11 (Protein kinase A-anchoring protein 11) (PRKA11) (A kinase anchor protein 220 kDa) (AKAP 220) (hAKAP220).

ARHG6_HUMAN
θ value	1.06291 (rank : 484)	NC score	0.176997 (rank : 137)
Query Neighborhood Hits	872	Target Neighborhood Hits	376	Shared Neighborhood Hits	128
SwissProt Accessions	Q15052, Q15396, Q5JQ66, Q86XH0	Gene names	ARHGEF6, COOL2, KIAA0006, PIXA
Domain Architecture
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).

CASC3_HUMAN
θ value	1.06291 (rank : 485)	NC score	0.040228 (rank : 831)
Query Neighborhood Hits	872	Target Neighborhood Hits	204	Shared Neighborhood Hits	49
SwissProt Accessions	O15234	Gene names	CASC3, MLN51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein) (Metastatic lymph node protein 51) (Protein MLN 51) (Protein barentsz) (Btz).

CCD95_HUMAN
θ value	1.06291 (rank : 486)	NC score	0.042044 (rank : 818)
Query Neighborhood Hits	872	Target Neighborhood Hits	25	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NBZ0	Gene names	CCDC95
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 95.

CO4A5_HUMAN
θ value	1.06291 (rank : 487)	NC score	0.085962 (rank : 426)
Query Neighborhood Hits	872	Target Neighborhood Hits	383	Shared Neighborhood Hits	143
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

COA2_HUMAN
θ value	1.06291 (rank : 488)	NC score	0.032954 (rank : 873)
Query Neighborhood Hits	872	Target Neighborhood Hits	184	Shared Neighborhood Hits	54
SwissProt Accessions	O00763, Q16852	Gene names	ACACB, ACC2, ACCB
Domain Architecture
Description	Acetyl-CoA carboxylase 2 (EC 6.4.1.2) (ACC-beta) [Includes: Biotin carboxylase (EC 6.3.4.14)].

COBA1_HUMAN
θ value	1.06291 (rank : 489)	NC score	0.094236 (rank : 360)
Query Neighborhood Hits	872	Target Neighborhood Hits	491	Shared Neighborhood Hits	157
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

CRKL_HUMAN
θ value	1.06291 (rank : 490)	NC score	0.165699 (rank : 158)
Query Neighborhood Hits	872	Target Neighborhood Hits	313	Shared Neighborhood Hits	136
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

CS016_HUMAN
θ value	1.06291 (rank : 491)	NC score	0.092655 (rank : 377)
Query Neighborhood Hits	872	Target Neighborhood Hits	310	Shared Neighborhood Hits	105
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

DEN1A_MOUSE
θ value	1.06291 (rank : 492)	NC score	0.037375 (rank : 847)
Query Neighborhood Hits	872	Target Neighborhood Hits	178	Shared Neighborhood Hits	71
SwissProt Accessions	Q8K382	Gene names	Dennd1a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

DOK3_MOUSE
θ value	1.06291 (rank : 493)	NC score	0.018335 (rank : 983)
Query Neighborhood Hits	872	Target Neighborhood Hits	25	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QZK7	Gene names	Dok3, Dokl
Domain Architecture	No domain graphic available
Description	Docking protein 3 (Downstream of tyrosine kinase 3) (P62(dok)-like protein) (DOK-L).

DUS2L_HUMAN
θ value	1.06291 (rank : 494)	NC score	0.019018 (rank : 977)
Query Neighborhood Hits	872	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NX74, Q4H4D9	Gene names	DUS2L, DUS2
Domain Architecture	No domain graphic available
Description	tRNA-dihydrouridine synthase 2-like (EC 1.-.-.-) (hDUS2) (Up-regulated in lung cancer) (URLC8).

DVL1_HUMAN
θ value	1.06291 (rank : 495)	NC score	0.028443 (rank : 906)
Query Neighborhood Hits	872	Target Neighborhood Hits	158	Shared Neighborhood Hits	22
SwissProt Accessions	O14640	Gene names	DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

EOMES_HUMAN
θ value	1.06291 (rank : 496)	NC score	0.004762 (rank : 1098)
Query Neighborhood Hits	872	Target Neighborhood Hits	57	Shared Neighborhood Hits	6
SwissProt Accessions	O95936, Q8TAZ2, Q9UPM7	Gene names	EOMES, TBR2
Domain Architecture
Description	Eomesodermin homolog.

FBLI1_HUMAN
θ value	1.06291 (rank : 497)	NC score	0.021675 (rank : 960)
Query Neighborhood Hits	872	Target Neighborhood Hits	200	Shared Neighborhood Hits	32
SwissProt Accessions	Q8WUP2, Q5VVE0, Q5VVE1, Q8IX23, Q96T00, Q9UFD6	Gene names	FBLIM1, FBLP1
Domain Architecture
Description	Filamin-binding LIM protein 1 (Filamin-binding LIM protein 1) (FBLP-1) (Mitogen-inducible 2-interacting protein) (MIG2-interacting protein) (Migfilin).

GLR_MOUSE
θ value	1.06291 (rank : 498)	NC score	0.006174 (rank : 1083)
Query Neighborhood Hits	872	Target Neighborhood Hits	79	Shared Neighborhood Hits	6
SwissProt Accessions	Q61606, Q63960	Gene names	Gcgr
Domain Architecture
Description	Glucagon receptor precursor (GL-R).

INSM1_HUMAN
θ value	1.06291 (rank : 499)	NC score	0.001577 (rank : 1113)
Query Neighborhood Hits	872	Target Neighborhood Hits	683	Shared Neighborhood Hits	41
SwissProt Accessions	Q01101	Gene names	INSM1, IA1
Domain Architecture	No domain graphic available
Description	Insulinoma-associated protein 1 (Zinc finger protein IA-1).

K0329_HUMAN
θ value	1.06291 (rank : 500)	NC score	0.029713 (rank : 892)
Query Neighborhood Hits	872	Target Neighborhood Hits	85	Shared Neighborhood Hits	11
SwissProt Accessions	O15040, Q9UEG6	Gene names	KIAA0329, KIAA0297
Domain Architecture
Description	Protein KIAA0329/KIAA0297.

LNP_HUMAN
θ value	1.06291 (rank : 501)	NC score	0.029555 (rank : 894)
Query Neighborhood Hits	872	Target Neighborhood Hits	62	Shared Neighborhood Hits	19
SwissProt Accessions	Q9C0E8, Q2M2V8, Q2YD99, Q658W8, Q8N5V9, Q96MS5	Gene names	LNP, KIAA1715
Domain Architecture	No domain graphic available
Description	Protein lunapark.

MBD5_HUMAN
θ value	1.06291 (rank : 502)	NC score	0.058397 (rank : 668)
Query Neighborhood Hits	872	Target Neighborhood Hits	176	Shared Neighborhood Hits	55
SwissProt Accessions	Q9P267, Q9NUV6	Gene names	MBD5, KIAA1461
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 5 (Methyl-CpG-binding protein MBD5).

MIA2_MOUSE
θ value	1.06291 (rank : 503)	NC score	0.047245 (rank : 794)
Query Neighborhood Hits	872	Target Neighborhood Hits	109	Shared Neighborhood Hits	34
SwissProt Accessions	Q91ZV0	Gene names	Mia2
Domain Architecture	No domain graphic available
Description	Melanoma inhibitory activity protein 2 precursor.

MYO15_MOUSE
θ value	1.06291 (rank : 504)	NC score	0.084758 (rank : 435)
Query Neighborhood Hits	872	Target Neighborhood Hits	467	Shared Neighborhood Hits	197
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

NCTR2_HUMAN
θ value	1.06291 (rank : 505)	NC score	0.033481 (rank : 871)
Query Neighborhood Hits	872	Target Neighborhood Hits	99	Shared Neighborhood Hits	30
SwissProt Accessions	O95944, Q9H562, Q9H563, Q9H564, Q9UMT1, Q9UMT2	Gene names	NCR2, LY95
Domain Architecture
Description	Natural cytotoxicity triggering receptor 2 precursor (Natural killer cell p44-related protein) (NKp44) (NK-p44) (NK cell-activating receptor) (Lymphocyte antigen 95 homolog) (CD336 antigen).

PKHA4_HUMAN
θ value	1.06291 (rank : 506)	NC score	0.062492 (rank : 615)
Query Neighborhood Hits	872	Target Neighborhood Hits	283	Shared Neighborhood Hits	79
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PSL1_HUMAN
θ value	1.06291 (rank : 507)	NC score	0.143670 (rank : 205)
Query Neighborhood Hits	872	Target Neighborhood Hits	650	Shared Neighborhood Hits	281
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

RU1C_MOUSE
θ value	1.06291 (rank : 508)	NC score	0.066717 (rank : 573)
Query Neighborhood Hits	872	Target Neighborhood Hits	83	Shared Neighborhood Hits	38
SwissProt Accessions	Q62241	Gene names	Snrp1c, Snrpc
Domain Architecture
Description	U1 small nuclear ribonucleoprotein C (U1 snRNP protein C) (U1C protein) (U1-C).

S23IP_MOUSE
θ value	1.06291 (rank : 509)	NC score	0.097102 (rank : 348)
Query Neighborhood Hits	872	Target Neighborhood Hits	363	Shared Neighborhood Hits	162
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

SEPT9_HUMAN
θ value	1.06291 (rank : 510)	NC score	0.077308 (rank : 491)
Query Neighborhood Hits	872	Target Neighborhood Hits	706	Shared Neighborhood Hits	221
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

SH3G1_HUMAN
θ value	1.06291 (rank : 511)	NC score	0.160877 (rank : 170)
Query Neighborhood Hits	872	Target Neighborhood Hits	307	Shared Neighborhood Hits	126
SwissProt Accessions	Q99961, Q99668	Gene names	SH3GL1, CNSA1, SH3D2B
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL).

SMCA4_HUMAN
θ value	1.06291 (rank : 512)	NC score	0.040378 (rank : 830)
Query Neighborhood Hits	872	Target Neighborhood Hits	597	Shared Neighborhood Hits	127
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

SP7_HUMAN
θ value	1.06291 (rank : 513)	NC score	0.005489 (rank : 1094)
Query Neighborhood Hits	872	Target Neighborhood Hits	734	Shared Neighborhood Hits	60
SwissProt Accessions	Q8TDD2	Gene names	SP7, OSX
Domain Architecture	No domain graphic available
Description	Transcription factor Sp7 (Zinc finger protein osterix).

SPR2F_MOUSE
θ value	1.06291 (rank : 514)	NC score	0.035437 (rank : 863)
Query Neighborhood Hits	872	Target Neighborhood Hits	43	Shared Neighborhood Hits	9
SwissProt Accessions	O70557	Gene names	Sprr2f
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F.

SSBP3_HUMAN
θ value	1.06291 (rank : 515)	NC score	0.062497 (rank : 613)
Query Neighborhood Hits	872	Target Neighborhood Hits	132	Shared Neighborhood Hits	75
SwissProt Accessions	Q9BWW4, Q9BTM0, Q9BWW3	Gene names	SSBP3, SSDP, SSDP1
Domain Architecture
Description	Single-stranded DNA-binding protein 3 (Sequence-specific single- stranded-DNA-binding protein).

SSBP3_MOUSE
θ value	1.06291 (rank : 516)	NC score	0.062497 (rank : 614)
Query Neighborhood Hits	872	Target Neighborhood Hits	132	Shared Neighborhood Hits	75
SwissProt Accessions	Q9D032, Q99LC6, Q9EQP3	Gene names	Ssbp3, Last, Ssdp1
Domain Architecture
Description	Single-stranded DNA-binding protein 3 (Sequence-specific single- stranded-DNA-binding protein) (Lck-associated signal transducer).

SYNG_MOUSE
θ value	1.06291 (rank : 517)	NC score	0.062467 (rank : 616)
Query Neighborhood Hits	872	Target Neighborhood Hits	206	Shared Neighborhood Hits	86
SwissProt Accessions	Q5SV85, Q5SV84, Q6PHT6	Gene names	Ap1gbp1, Syng
Domain Architecture	No domain graphic available
Description	AP1 subunit gamma-binding protein 1 (Gamma-synergin).

SYTL5_HUMAN
θ value	1.06291 (rank : 518)	NC score	0.017183 (rank : 994)
Query Neighborhood Hits	872	Target Neighborhood Hits	237	Shared Neighborhood Hits	28
SwissProt Accessions	Q8TDW5	Gene names	SYTL5, SLP5
Domain Architecture
Description	Synaptotagmin-like protein 5.

UBP21_MOUSE
θ value	1.06291 (rank : 519)	NC score	0.005991 (rank : 1087)
Query Neighborhood Hits	872	Target Neighborhood Hits	101	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QZL6, Q9D0R1	Gene names	Usp21, Usp23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21).

VASP_MOUSE
θ value	1.06291 (rank : 520)	NC score	0.062805 (rank : 608)
Query Neighborhood Hits	872	Target Neighborhood Hits	195	Shared Neighborhood Hits	66
SwissProt Accessions	P70460, Q3TAP0, Q3TCD2, Q3U0C2, Q3UDF1, Q91VD2, Q9R214	Gene names	Vasp
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

ZC3H3_MOUSE
θ value	1.06291 (rank : 521)	NC score	0.025666 (rank : 925)
Query Neighborhood Hits	872	Target Neighborhood Hits	188	Shared Neighborhood Hits	51
SwissProt Accessions	Q8CHP0, Q80X78	Gene names	Zc3h3, Kiaa0150, Zc3hdc3, Zfp623
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

ZIMP7_HUMAN
θ value	1.06291 (rank : 522)	NC score	0.075683 (rank : 506)
Query Neighborhood Hits	872	Target Neighborhood Hits	290	Shared Neighborhood Hits	130
SwissProt Accessions	Q8NF64, O94790, Q659A8, Q6JKL5, Q8WTX8, Q96Q01, Q9BQH7	Gene names	ZIMP7, KIAA1886
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

ZN598_HUMAN
θ value	1.06291 (rank : 523)	NC score	0.051592 (rank : 759)
Query Neighborhood Hits	872	Target Neighborhood Hits	339	Shared Neighborhood Hits	73
SwissProt Accessions	Q86UK7, Q8IW49, Q8N3D9, Q96FG3, Q9H7J3	Gene names	ZNF598
Domain Architecture	No domain graphic available
Description	Zinc finger protein 598.

ZNFX1_HUMAN
θ value	1.06291 (rank : 524)	NC score	0.013175 (rank : 1022)
Query Neighborhood Hits	872	Target Neighborhood Hits	308	Shared Neighborhood Hits	15
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

CHSS3_HUMAN
θ value	1.38821 (rank : 525)	NC score	0.014739 (rank : 1006)
Query Neighborhood Hits	872	Target Neighborhood Hits	97	Shared Neighborhood Hits	21
SwissProt Accessions	Q70JA7, Q76L22, Q86Y52	Gene names	CSS3, CHSY2
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate synthase 3 (EC 2.4.1.175) (Glucuronosyl-N- acetylgalactosaminyl-proteoglycan 4-beta-N- acetylgalactosaminyltransferase II) (Chondroitin synthase 2) (N- acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase II) (EC 2.4.1.226) (Chondroitin glucuronyltransferase II) (N- acetylgalactosaminyltransferase II) (Carbohydrate synthase 2).

CND2_HUMAN
θ value	1.38821 (rank : 526)	NC score	0.027268 (rank : 910)
Query Neighborhood Hits	872	Target Neighborhood Hits	26	Shared Neighborhood Hits	9
SwissProt Accessions	Q15003, Q8TB87	Gene names	NCAPH, BRRN, BRRN1, CAPH, KIAA0074
Domain Architecture
Description	Condensin complex subunit 2 (Non-SMC condensin I complex subunit H) (Barren homolog protein 1) (Chromosome-associated protein H) (hCAP-H) (XCAP-H homolog).

CO1A1_HUMAN
θ value	1.38821 (rank : 527)	NC score	0.096791 (rank : 351)
Query Neighborhood Hits	872	Target Neighborhood Hits	475	Shared Neighborhood Hits	157
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CO2A1_HUMAN
θ value	1.38821 (rank : 528)	NC score	0.093112 (rank : 371)
Query Neighborhood Hits	872	Target Neighborhood Hits	486	Shared Neighborhood Hits	174
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CO2A1_MOUSE
θ value	1.38821 (rank : 529)	NC score	0.089343 (rank : 398)
Query Neighborhood Hits	872	Target Neighborhood Hits	483	Shared Neighborhood Hits	156
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CSPG5_HUMAN
θ value	1.38821 (rank : 530)	NC score	0.070112 (rank : 542)
Query Neighborhood Hits	872	Target Neighborhood Hits	199	Shared Neighborhood Hits	84
SwissProt Accessions	O95196, Q71M39, Q71M40	Gene names	CSPG5, CALEB, NGC
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

DEN1A_HUMAN
θ value	1.38821 (rank : 531)	NC score	0.041799 (rank : 820)
Query Neighborhood Hits	872	Target Neighborhood Hits	176	Shared Neighborhood Hits	76
SwissProt Accessions	Q8TEH3, Q5VWF0, Q8IVD6, Q9H796	Gene names	DENND1A
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

DTX1_MOUSE
θ value	1.38821 (rank : 532)	NC score	0.024536 (rank : 934)
Query Neighborhood Hits	872	Target Neighborhood Hits	99	Shared Neighborhood Hits	35
SwissProt Accessions	Q61010, Q3TER5, Q8C2H2, Q9ER09	Gene names	Dtx1
Domain Architecture
Description	Protein deltex-1 (Deltex-1) (Deltex1) (mDTX1) (FXI-T1).

EPN2_HUMAN
θ value	1.38821 (rank : 533)	NC score	0.059587 (rank : 646)
Query Neighborhood Hits	872	Target Neighborhood Hits	156	Shared Neighborhood Hits	55
SwissProt Accessions	O95208, O95207, Q9H7Z2, Q9UPT7	Gene names	EPN2, KIAA1065
Domain Architecture
Description	Epsin-2 (EPS-15-interacting protein 2).

FHOD1_HUMAN
θ value	1.38821 (rank : 534)	NC score	0.066893 (rank : 570)
Query Neighborhood Hits	872	Target Neighborhood Hits	184	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y613, Q59F76, Q6Y1F2, Q76MS8, Q8N521	Gene names	FHOD1, FHOS
Domain Architecture
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

FOXC2_HUMAN
θ value	1.38821 (rank : 535)	NC score	0.022882 (rank : 945)
Query Neighborhood Hits	872	Target Neighborhood Hits	236	Shared Neighborhood Hits	71
SwissProt Accessions	Q99958	Gene names	FOXC2, FKHL14, MFH1
Domain Architecture
Description	Forkhead box protein C2 (Forkhead-related protein FKHL14) (Mesenchyme fork head protein 1) (MFH-1 protein) (Transcription factor FKH-14).

JADE2_MOUSE
θ value	1.38821 (rank : 536)	NC score	0.079204 (rank : 477)
Query Neighborhood Hits	872	Target Neighborhood Hits	560	Shared Neighborhood Hits	193
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

KLF1_MOUSE
θ value	1.38821 (rank : 537)	NC score	0.002200 (rank : 1111)
Query Neighborhood Hits	872	Target Neighborhood Hits	714	Shared Neighborhood Hits	44
SwissProt Accessions	P46099, O70261	Gene names	Klf1, Elkf
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 1 (Erythroid krueppel-like transcription factor) (EKLF) (Erythroid transcription factor).

MEGF9_MOUSE
θ value	1.38821 (rank : 538)	NC score	0.069071 (rank : 551)
Query Neighborhood Hits	872	Target Neighborhood Hits	896	Shared Neighborhood Hits	229
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MNT_HUMAN
θ value	1.38821 (rank : 539)	NC score	0.091069 (rank : 388)
Query Neighborhood Hits	872	Target Neighborhood Hits	496	Shared Neighborhood Hits	161
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

NMDE3_HUMAN
θ value	1.38821 (rank : 540)	NC score	0.023844 (rank : 938)
Query Neighborhood Hits	872	Target Neighborhood Hits	110	Shared Neighborhood Hits	22
SwissProt Accessions	Q14957	Gene names	GRIN2C
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 3 precursor (N-methyl D- aspartate receptor subtype 2C) (NR2C) (NMDAR2C).

PDC6I_HUMAN
θ value	1.38821 (rank : 541)	NC score	0.062854 (rank : 607)
Query Neighborhood Hits	872	Target Neighborhood Hits	278	Shared Neighborhood Hits	83
SwissProt Accessions	Q8WUM4, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5	Gene names	PDCD6IP, AIP1, ALIX, KIAA1375
Domain Architecture
Description	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95).

RANB9_HUMAN
θ value	1.38821 (rank : 542)	NC score	0.041437 (rank : 823)
Query Neighborhood Hits	872	Target Neighborhood Hits	179	Shared Neighborhood Hits	72
SwissProt Accessions	Q96S59, O94764, Q6P3T7, Q7LBR2, Q7Z7F9	Gene names	RANBP9, RANBPM
Domain Architecture	No domain graphic available
Description	Ran-binding protein 9 (RanBP9) (RanBP7) (Ran-binding protein M) (RanBPM) (BPM90) (BPM-L).

RAVR1_MOUSE
θ value	1.38821 (rank : 543)	NC score	0.028543 (rank : 901)
Query Neighborhood Hits	872	Target Neighborhood Hits	179	Shared Neighborhood Hits	31
SwissProt Accessions	Q9CW46, Q5DTT6, Q811K0, Q8C3Z1, Q8CA14	Gene names	Raver1, Kiaa1978
Domain Architecture	No domain graphic available
Description	Ribonucleoprotein PTB-binding 1 (Protein raver-1).

RBM12_HUMAN
θ value	1.38821 (rank : 544)	NC score	0.060128 (rank : 640)
Query Neighborhood Hits	872	Target Neighborhood Hits	298	Shared Neighborhood Hits	91
SwissProt Accessions	Q9NTZ6, O94865, Q8N3B1, Q9H196	Gene names	RBM12, KIAA0765
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

RGP1_HUMAN
θ value	1.38821 (rank : 545)	NC score	0.020919 (rank : 967)
Query Neighborhood Hits	872	Target Neighborhood Hits	124	Shared Neighborhood Hits	9
SwissProt Accessions	P46060	Gene names	RANGAP1
Domain Architecture
Description	Ran GTPase-activating protein 1.

RUSC1_MOUSE
θ value	1.38821 (rank : 546)	NC score	0.114797 (rank : 285)
Query Neighborhood Hits	872	Target Neighborhood Hits	206	Shared Neighborhood Hits	103
SwissProt Accessions	Q8BG26, Q6PHT9	Gene names	Rusc1
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1.

SEM6B_MOUSE
θ value	1.38821 (rank : 547)	NC score	0.030403 (rank : 889)
Query Neighborhood Hits	872	Target Neighborhood Hits	200	Shared Neighborhood Hits	95
SwissProt Accessions	O54951	Gene names	Sema6b, Seman
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin VIB) (Sema VIB) (Semaphorin N) (Sema N).

SIN3A_HUMAN
θ value	1.38821 (rank : 548)	NC score	0.034092 (rank : 866)
Query Neighborhood Hits	872	Target Neighborhood Hits	180	Shared Neighborhood Hits	66
SwissProt Accessions	Q96ST3, Q8N8N4, Q8NC83, Q8WV18, Q96L98, Q9UFQ1	Gene names	SIN3A
Domain Architecture
Description	Paired amphipathic helix protein Sin3a (Transcriptional corepressor Sin3a) (Histone deacetylase complex subunit Sin3a).

SRBS1_HUMAN
θ value	1.38821 (rank : 549)	NC score	0.201679 (rank : 102)
Query Neighborhood Hits	872	Target Neighborhood Hits	396	Shared Neighborhood Hits	163
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

STF1_MOUSE
θ value	1.38821 (rank : 550)	NC score	0.011834 (rank : 1039)
Query Neighborhood Hits	872	Target Neighborhood Hits	137	Shared Neighborhood Hits	23
SwissProt Accessions	P33242	Gene names	Nr5a1, Ftzf1
Domain Architecture
Description	Steroidogenic factor 1 (STF-1) (SF-1) (Adrenal 4-binding protein) (Steroid hormone receptor Ad4BP) (Fushi tarazu factor homolog 1) (Embryonal LTR-binding protein) (ELP) (Embryonal long terminal repeat- binding protein) (Steroid hydroxylase positive regulator).

SYFB_HUMAN
θ value	1.38821 (rank : 551)	NC score	0.028499 (rank : 904)
Query Neighborhood Hits	872	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NSD9, O95708, Q9NZZ6	Gene names	FARSLB, FARSB, FRSB
Domain Architecture
Description	Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) (Phenylalanine-- tRNA ligase beta chain) (PheRS).

TOM40_MOUSE
θ value	1.38821 (rank : 552)	NC score	0.013811 (rank : 1015)
Query Neighborhood Hits	872	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QYA2, Q9Z2N1	Gene names	Tomm40, Mom35, Tom40
Domain Architecture
Description	Probable mitochondrial import receptor subunit TOM40 homolog (Translocase of outer membrane 40 kDa subunit homolog).

WHRN_HUMAN
θ value	1.38821 (rank : 553)	NC score	0.029310 (rank : 895)
Query Neighborhood Hits	872	Target Neighborhood Hits	325	Shared Neighborhood Hits	72
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

AB1IP_MOUSE
θ value	1.81305 (rank : 554)	NC score	0.062419 (rank : 617)
Query Neighborhood Hits	872	Target Neighborhood Hits	181	Shared Neighborhood Hits	58
SwissProt Accessions	Q8R5A3, O35329, Q8BRU0, Q99KV8	Gene names	Apbb1ip, Prel1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 48).

ASPP2_HUMAN
θ value	1.81305 (rank : 555)	NC score	0.115399 (rank : 282)
Query Neighborhood Hits	872	Target Neighborhood Hits	1156	Shared Neighborhood Hits	221
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

B3GT6_HUMAN
θ value	1.81305 (rank : 556)	NC score	0.011386 (rank : 1042)
Query Neighborhood Hits	872	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q96L58, Q5T7M5	Gene names	B3GALT6
Domain Architecture	No domain graphic available
Description	Beta-1,3-galactosyltransferase 6 (EC 2.4.1.134) (beta 3GalT6) (Galactosylxylosylprotein 3-beta-galactosyltransferase) (UDP- Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6) (Galactosyltransferase II) (GAG GalTII).

BAG4_HUMAN
θ value	1.81305 (rank : 557)	NC score	0.026171 (rank : 922)
Query Neighborhood Hits	872	Target Neighborhood Hits	96	Shared Neighborhood Hits	23
SwissProt Accessions	O95429, O95818	Gene names	BAG4, SODD
Domain Architecture
Description	BAG family molecular chaperone regulator 4 (BCL2-associated athanogene 4) (BAG-4) (Silencer of death domains).

CAC1H_HUMAN
θ value	1.81305 (rank : 558)	NC score	0.023788 (rank : 939)
Query Neighborhood Hits	872	Target Neighborhood Hits	307	Shared Neighborhood Hits	81
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

CITE4_HUMAN
θ value	1.81305 (rank : 559)	NC score	0.064506 (rank : 595)
Query Neighborhood Hits	872	Target Neighborhood Hits	67	Shared Neighborhood Hits	33
SwissProt Accessions	Q96RK1	Gene names	CITED4, MRG2
Domain Architecture	No domain graphic available
Description	Cbp/p300-interacting transactivator 4 (MSG1-related protein 2) (MRG- 2).

CO4A1_MOUSE
θ value	1.81305 (rank : 560)	NC score	0.088986 (rank : 400)
Query Neighborhood Hits	872	Target Neighborhood Hits	450	Shared Neighborhood Hits	157
SwissProt Accessions	P02463	Gene names	Col4a1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

COBA2_HUMAN
θ value	1.81305 (rank : 561)	NC score	0.085935 (rank : 427)
Query Neighborhood Hits	872	Target Neighborhood Hits	408	Shared Neighborhood Hits	127
SwissProt Accessions	P13942, Q07751, Q13271, Q13272, Q13273, Q99866, Q9UIP9	Gene names	COL11A2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

CRKL_MOUSE
θ value	1.81305 (rank : 562)	NC score	0.157122 (rank : 178)
Query Neighborhood Hits	872	Target Neighborhood Hits	307	Shared Neighborhood Hits	130
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

EMID1_HUMAN
θ value	1.81305 (rank : 563)	NC score	0.070402 (rank : 540)
Query Neighborhood Hits	872	Target Neighborhood Hits	215	Shared Neighborhood Hits	92
SwissProt Accessions	Q96A84, Q6ICG1, Q86SS7	Gene names	EMID1, EMU1
Domain Architecture	No domain graphic available
Description	EMI domain-containing protein 1 precursor (Protein Emu1) (Emilin and multimerin domain-containing protein 1).

FGD1_MOUSE
θ value	1.81305 (rank : 564)	NC score	0.086837 (rank : 417)
Query Neighborhood Hits	872	Target Neighborhood Hits	387	Shared Neighborhood Hits	143
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FOXE3_MOUSE
θ value	1.81305 (rank : 565)	NC score	0.012833 (rank : 1025)
Query Neighborhood Hits	872	Target Neighborhood Hits	118	Shared Neighborhood Hits	26
SwissProt Accessions	Q9QY14	Gene names	Foxe3
Domain Architecture
Description	Forkhead box protein E3.

GDF6_MOUSE
θ value	1.81305 (rank : 566)	NC score	0.002805 (rank : 1108)
Query Neighborhood Hits	872	Target Neighborhood Hits	68	Shared Neighborhood Hits	4
SwissProt Accessions	P43028, Q70UT4	Gene names	Gdf6, Gdf-6, Gdf16
Domain Architecture	No domain graphic available
Description	Growth/differentiation factor 6 precursor (GDF-6) (Growth/differentiation factor 16).

GRIN2_HUMAN
θ value	1.81305 (rank : 567)	NC score	0.028546 (rank : 900)
Query Neighborhood Hits	872	Target Neighborhood Hits	53	Shared Neighborhood Hits	15
SwissProt Accessions	O60269, Q5SVF0	Gene names	GPRIN2, KIAA0514
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 2 (GRIN2).

HNRL1_MOUSE
θ value	1.81305 (rank : 568)	NC score	0.033902 (rank : 869)
Query Neighborhood Hits	872	Target Neighborhood Hits	200	Shared Neighborhood Hits	60
SwissProt Accessions	Q8VDM6, Q3U201, Q3UPB0, Q6AZA7, Q8BY45, Q8K365	Gene names	Hnrpul1
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1.

K0310_HUMAN
θ value	1.81305 (rank : 569)	NC score	0.098129 (rank : 340)
Query Neighborhood Hits	872	Target Neighborhood Hits	420	Shared Neighborhood Hits	166
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

K1949_MOUSE
θ value	1.81305 (rank : 570)	NC score	0.043701 (rank : 813)
Query Neighborhood Hits	872	Target Neighborhood Hits	134	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BQ30, Q3UDS6, Q8CEY9, Q8R3D8	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA1949 homolog.

MKL1_MOUSE
θ value	1.81305 (rank : 571)	NC score	0.127104 (rank : 246)
Query Neighborhood Hits	872	Target Neighborhood Hits	667	Shared Neighborhood Hits	284
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

NCF1_MOUSE
θ value	1.81305 (rank : 572)	NC score	0.160976 (rank : 169)
Query Neighborhood Hits	872	Target Neighborhood Hits	198	Shared Neighborhood Hits	110
SwissProt Accessions	Q09014, O70144, Q9JI34	Gene names	Ncf1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K).

NRX2A_HUMAN
θ value	1.81305 (rank : 573)	NC score	0.097856 (rank : 343)
Query Neighborhood Hits	872	Target Neighborhood Hits	614	Shared Neighborhood Hits	269
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NRX2B_HUMAN
θ value	1.81305 (rank : 574)	NC score	0.145057 (rank : 202)
Query Neighborhood Hits	872	Target Neighborhood Hits	481	Shared Neighborhood Hits	257
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

P85B_MOUSE
θ value	1.81305 (rank : 575)	NC score	0.106843 (rank : 314)
Query Neighborhood Hits	872	Target Neighborhood Hits	519	Shared Neighborhood Hits	72
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

PACN1_HUMAN
θ value	1.81305 (rank : 576)	NC score	0.147121 (rank : 199)
Query Neighborhood Hits	872	Target Neighborhood Hits	320	Shared Neighborhood Hits	126
SwissProt Accessions	Q9BY11, Q9P2G8	Gene names	PACSIN1, KIAA1379
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

PACN1_MOUSE
θ value	1.81305 (rank : 577)	NC score	0.147390 (rank : 198)
Query Neighborhood Hits	872	Target Neighborhood Hits	283	Shared Neighborhood Hits	123
SwissProt Accessions	Q61644	Gene names	Pacsin1, Pacsin
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

PCD15_HUMAN
θ value	1.81305 (rank : 578)	NC score	0.002830 (rank : 1107)
Query Neighborhood Hits	872	Target Neighborhood Hits	289	Shared Neighborhood Hits	48
SwissProt Accessions	Q96QU1, Q96QT8	Gene names	PCDH15
Domain Architecture
Description	Protocadherin-15 precursor.

PER1_HUMAN
θ value	1.81305 (rank : 579)	NC score	0.041648 (rank : 822)
Query Neighborhood Hits	872	Target Neighborhood Hits	215	Shared Neighborhood Hits	70
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

PHC2_HUMAN
θ value	1.81305 (rank : 580)	NC score	0.088948 (rank : 402)
Query Neighborhood Hits	872	Target Neighborhood Hits	388	Shared Neighborhood Hits	153
SwissProt Accessions	Q8IXK0, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7	Gene names	PHC2, EDR2, PH2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2).

PRCC_HUMAN
θ value	1.81305 (rank : 581)	NC score	0.044628 (rank : 805)
Query Neighborhood Hits	872	Target Neighborhood Hits	109	Shared Neighborhood Hits	42
SwissProt Accessions	Q92733, O00665, O00724	Gene names	PRCC, TPRC
Domain Architecture	No domain graphic available
Description	Proline-rich protein PRCC (Papillary renal cell carcinoma translocation-associated gene protein).

RUSC1_HUMAN
θ value	1.81305 (rank : 582)	NC score	0.117889 (rank : 272)
Query Neighborhood Hits	872	Target Neighborhood Hits	226	Shared Neighborhood Hits	115
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

SH3G3_MOUSE
θ value	1.81305 (rank : 583)	NC score	0.159309 (rank : 172)
Query Neighborhood Hits	872	Target Neighborhood Hits	236	Shared Neighborhood Hits	120
SwissProt Accessions	Q62421	Gene names	Sh3gl3, Sh3d2c, Sh3d2c2
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (SH3p13).

TITIN_HUMAN
θ value	1.81305 (rank : 584)	NC score	0.006085 (rank : 1085)
Query Neighborhood Hits	872	Target Neighborhood Hits	2923	Shared Neighborhood Hits	230
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

TLE1_HUMAN
θ value	1.81305 (rank : 585)	NC score	0.039191 (rank : 840)
Query Neighborhood Hits	872	Target Neighborhood Hits	485	Shared Neighborhood Hits	149
SwissProt Accessions	Q04724, Q5T3G4, Q969V9	Gene names	TLE1
Domain Architecture
Description	Transducin-like enhancer protein 1 (ESG1) (E(Sp1) homolog).

UBP43_HUMAN
θ value	1.81305 (rank : 586)	NC score	0.014184 (rank : 1011)
Query Neighborhood Hits	872	Target Neighborhood Hits	144	Shared Neighborhood Hits	33
SwissProt Accessions	Q70EL4, Q8N2C5, Q96DQ6	Gene names	USP43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

CEBPE_HUMAN
θ value	2.36792 (rank : 587)	NC score	0.052289 (rank : 750)
Query Neighborhood Hits	872	Target Neighborhood Hits	236	Shared Neighborhood Hits	106
SwissProt Accessions	Q15744, Q15745, Q8IYI2, Q99803	Gene names	CEBPE
Domain Architecture
Description	CCAAT/enhancer-binding protein epsilon (C/EBP epsilon).

CG1_HUMAN
θ value	2.36792 (rank : 588)	NC score	0.065438 (rank : 585)
Query Neighborhood Hits	872	Target Neighborhood Hits	222	Shared Neighborhood Hits	91
SwissProt Accessions	Q13495	Gene names	CXorf6, CG1
Domain Architecture	No domain graphic available
Description	CG1 protein (F18).

CO4A3_HUMAN
θ value	2.36792 (rank : 589)	NC score	0.093904 (rank : 365)
Query Neighborhood Hits	872	Target Neighborhood Hits	421	Shared Neighborhood Hits	151
SwissProt Accessions	Q01955, Q9BQT2	Gene names	COL4A3
Domain Architecture
Description	Collagen alpha-3(IV) chain precursor (Goodpasture antigen).

CP007_MOUSE
θ value	2.36792 (rank : 590)	NC score	0.059315 (rank : 651)
Query Neighborhood Hits	872	Target Neighborhood Hits	231	Shared Neighborhood Hits	76
SwissProt Accessions	Q8C190, Q6PFD1	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf7 homolog (5-day ovary-specific transcript 1 protein).

CPSF7_HUMAN
θ value	2.36792 (rank : 591)	NC score	0.065801 (rank : 579)
Query Neighborhood Hits	872	Target Neighborhood Hits	125	Shared Neighborhood Hits	43
SwissProt Accessions	Q8N684, Q7Z3H9, Q9H025, Q9H9V1	Gene names	CPSF7
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 7 (Cleavage and polyadenylation specificity factor 59 kDa subunit) (CPSF 59 kDa subunit) (Pre-mRNA cleavage factor Im 59 kDa subunit).

CPSF7_MOUSE
θ value	2.36792 (rank : 592)	NC score	0.065784 (rank : 580)
Query Neighborhood Hits	872	Target Neighborhood Hits	123	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BTV2, Q3TNF1, Q8BKE7, Q8CFS8	Gene names	Cpsf7
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 7.

DLG4_HUMAN
θ value	2.36792 (rank : 593)	NC score	0.024688 (rank : 932)
Query Neighborhood Hits	872	Target Neighborhood Hits	286	Shared Neighborhood Hits	71
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG4_MOUSE
θ value	2.36792 (rank : 594)	NC score	0.023021 (rank : 943)
Query Neighborhood Hits	872	Target Neighborhood Hits	282	Shared Neighborhood Hits	69
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DOCK1_HUMAN
θ value	2.36792 (rank : 595)	NC score	0.053673 (rank : 736)
Query Neighborhood Hits	872	Target Neighborhood Hits	191	Shared Neighborhood Hits	86
SwissProt Accessions	Q14185	Gene names	DOCK1
Domain Architecture
Description	Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180).

DUT_HUMAN
θ value	2.36792 (rank : 596)	NC score	0.040822 (rank : 826)
Query Neighborhood Hits	872	Target Neighborhood Hits	52	Shared Neighborhood Hits	28
SwissProt Accessions	P33316, O14785, Q16708, Q16860, Q96Q81	Gene names	DUT
Domain Architecture
Description	Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial precursor (EC 3.6.1.23) (dUTPase) (dUTP pyrophosphatase).

EHMT2_MOUSE
θ value	2.36792 (rank : 597)	NC score	0.053899 (rank : 733)
Query Neighborhood Hits	872	Target Neighborhood Hits	750	Shared Neighborhood Hits	175
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

FIP1_HUMAN
θ value	2.36792 (rank : 598)	NC score	0.044166 (rank : 808)
Query Neighborhood Hits	872	Target Neighborhood Hits	118	Shared Neighborhood Hits	36
SwissProt Accessions	Q6UN15, Q499Y4, Q49AU3, Q7Z608, Q8WVN3, Q96F80, Q9H077	Gene names	FIP1L1, FIP1, RHE
Domain Architecture	No domain graphic available
Description	Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1) (Factor interacting with PAP) (hFip1) (Rearranged in hypereosinophilia).

FOXC1_MOUSE
θ value	2.36792 (rank : 599)	NC score	0.022862 (rank : 946)
Query Neighborhood Hits	872	Target Neighborhood Hits	218	Shared Neighborhood Hits	56
SwissProt Accessions	Q61572, O88409, Q61582	Gene names	Foxc1, Fkh1, Fkhl7, Freac3, Mf1
Domain Architecture
Description	Forkhead box protein C1 (Forkhead-related protein FKHL7) (Forkhead- related transcription factor 3) (FREAC-3) (Transcription factor FKH-1) (Mesoderm/mesenchyme forkhead 1) (MF-1).

IRX3_HUMAN
θ value	2.36792 (rank : 600)	NC score	0.026362 (rank : 921)
Query Neighborhood Hits	872	Target Neighborhood Hits	342	Shared Neighborhood Hits	61
SwissProt Accessions	P78415, Q7Z4A4, Q7Z4A5, Q8IVC6	Gene names	IRX3, IRXB1
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-3 (Iroquois homeobox protein 3) (Homeodomain protein IRXB1).

KLF14_HUMAN
θ value	2.36792 (rank : 601)	NC score	-0.000009 (rank : 1122)
Query Neighborhood Hits	872	Target Neighborhood Hits	725	Shared Neighborhood Hits	41
SwissProt Accessions	Q8TD94	Gene names	KLF14, BTEB5
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 14 (Transcription factor BTEB5) (Basic transcription element-binding protein 5) (BTE-binding protein 5).

LEG3_HUMAN
θ value	2.36792 (rank : 602)	NC score	0.032555 (rank : 879)
Query Neighborhood Hits	872	Target Neighborhood Hits	124	Shared Neighborhood Hits	51
SwissProt Accessions	P17931, Q16005, Q96J47	Gene names	LGALS3, MAC2
Domain Architecture
Description	Galectin-3 (Galactose-specific lectin 3) (Mac-2 antigen) (IgE-binding protein) (35 kDa lectin) (Carbohydrate-binding protein 35) (CBP 35) (Laminin-binding protein) (Lectin L-29) (L-31) (Galactoside-binding protein) (GALBP).

MATK_MOUSE
θ value	2.36792 (rank : 603)	NC score	0.014860 (rank : 1004)
Query Neighborhood Hits	872	Target Neighborhood Hits	952	Shared Neighborhood Hits	80
SwissProt Accessions	P41242, Q6LE90	Gene names	Matk, Ctk, Ntk
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK).

MICA1_HUMAN
θ value	2.36792 (rank : 604)	NC score	0.018779 (rank : 978)
Query Neighborhood Hits	872	Target Neighborhood Hits	279	Shared Neighborhood Hits	48
SwissProt Accessions	Q8TDZ2, Q7Z633, Q8IVS9, Q96G47, Q9H6X6, Q9H7I0, Q9HAA1, Q9UFF7	Gene names	MICAL1, MICAL, NICAL
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

MINT_MOUSE
θ value	2.36792 (rank : 605)	NC score	0.108186 (rank : 309)
Query Neighborhood Hits	872	Target Neighborhood Hits	1514	Shared Neighborhood Hits	310
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MK07_HUMAN
θ value	2.36792 (rank : 606)	NC score	0.006030 (rank : 1086)
Query Neighborhood Hits	872	Target Neighborhood Hits	1087	Shared Neighborhood Hits	125
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

MK15_HUMAN
θ value	2.36792 (rank : 607)	NC score	0.011269 (rank : 1045)
Query Neighborhood Hits	872	Target Neighborhood Hits	1038	Shared Neighborhood Hits	139
SwissProt Accessions	Q8TD08, Q2TCF9, Q8N362	Gene names	MAPK15, ERK8
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 8).

NOTC4_MOUSE
θ value	2.36792 (rank : 608)	NC score	0.015901 (rank : 998)
Query Neighborhood Hits	872	Target Neighborhood Hits	872	Shared Neighborhood Hits	46
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

PCQAP_HUMAN
θ value	2.36792 (rank : 609)	NC score	0.073503 (rank : 515)
Query Neighborhood Hits	872	Target Neighborhood Hits	549	Shared Neighborhood Hits	110
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

PELP1_HUMAN
θ value	2.36792 (rank : 610)	NC score	0.065760 (rank : 581)
Query Neighborhood Hits	872	Target Neighborhood Hits	596	Shared Neighborhood Hits	115
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

PER3_HUMAN
θ value	2.36792 (rank : 611)	NC score	0.087605 (rank : 410)
Query Neighborhood Hits	872	Target Neighborhood Hits	479	Shared Neighborhood Hits	182
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

PHLPP_HUMAN
θ value	2.36792 (rank : 612)	NC score	0.019376 (rank : 976)
Query Neighborhood Hits	872	Target Neighborhood Hits	604	Shared Neighborhood Hits	122
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

PI5PA_MOUSE
θ value	2.36792 (rank : 613)	NC score	0.086397 (rank : 421)
Query Neighborhood Hits	872	Target Neighborhood Hits	331	Shared Neighborhood Hits	124
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PO121_HUMAN
θ value	2.36792 (rank : 614)	NC score	0.065545 (rank : 583)
Query Neighborhood Hits	872	Target Neighborhood Hits	344	Shared Neighborhood Hits	86
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

RBM16_HUMAN
θ value	2.36792 (rank : 615)	NC score	0.067876 (rank : 564)
Query Neighborhood Hits	872	Target Neighborhood Hits	300	Shared Neighborhood Hits	98
SwissProt Accessions	Q9UPN6, Q5TBU6, Q9BQN8, Q9BX43	Gene names	RBM16, KIAA1116
Domain Architecture
Description	Putative RNA-binding protein 16 (RNA-binding motif protein 16).

RU1C_HUMAN
θ value	2.36792 (rank : 616)	NC score	0.061139 (rank : 626)
Query Neighborhood Hits	872	Target Neighborhood Hits	81	Shared Neighborhood Hits	37
SwissProt Accessions	P09234	Gene names	SNRPC
Domain Architecture
Description	U1 small nuclear ribonucleoprotein C (U1 snRNP protein C) (U1C protein) (U1-C).

SF3B2_HUMAN
θ value	2.36792 (rank : 617)	NC score	0.035676 (rank : 860)
Query Neighborhood Hits	872	Target Neighborhood Hits	157	Shared Neighborhood Hits	34
SwissProt Accessions	Q13435	Gene names	SF3B2, SAP145
Domain Architecture
Description	Splicing factor 3B subunit 2 (Spliceosome-associated protein 145) (SAP 145) (SF3b150) (Pre-mRNA-splicing factor SF3b 145 kDa subunit).

SH3G2_HUMAN
θ value	2.36792 (rank : 618)	NC score	0.164830 (rank : 162)
Query Neighborhood Hits	872	Target Neighborhood Hits	324	Shared Neighborhood Hits	126
SwissProt Accessions	Q99962, Q9NQK5	Gene names	SH3GL2, CNSA2, SH3D2A
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (EEN-B1).

SH3G3_HUMAN
θ value	2.36792 (rank : 619)	NC score	0.158416 (rank : 174)
Query Neighborhood Hits	872	Target Neighborhood Hits	222	Shared Neighborhood Hits	116
SwissProt Accessions	Q99963, O43553, O43554	Gene names	SH3GL3, CNSA3, SH3D2C
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (EEN-B2).

SMR1_MOUSE
θ value	2.36792 (rank : 620)	NC score	0.059996 (rank : 644)
Query Neighborhood Hits	872	Target Neighborhood Hits	103	Shared Neighborhood Hits	50
SwissProt Accessions	Q61900	Gene names	Smr1, Msg1
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 1 precursor (Salivary protein MSG1).

SPT5H_HUMAN
θ value	2.36792 (rank : 621)	NC score	0.136758 (rank : 222)
Query Neighborhood Hits	872	Target Neighborhood Hits	436	Shared Neighborhood Hits	201
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

SPT5H_MOUSE
θ value	2.36792 (rank : 622)	NC score	0.136712 (rank : 223)
Query Neighborhood Hits	872	Target Neighborhood Hits	437	Shared Neighborhood Hits	198
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

SRBS1_MOUSE
θ value	2.36792 (rank : 623)	NC score	0.207679 (rank : 96)
Query Neighborhood Hits	872	Target Neighborhood Hits	409	Shared Neighborhood Hits	176
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SRRM2_MOUSE
θ value	2.36792 (rank : 624)	NC score	0.119626 (rank : 265)
Query Neighborhood Hits	872	Target Neighborhood Hits	1470	Shared Neighborhood Hits	283
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TM16H_HUMAN
θ value	2.36792 (rank : 625)	NC score	0.025024 (rank : 931)
Query Neighborhood Hits	872	Target Neighborhood Hits	139	Shared Neighborhood Hits	42
SwissProt Accessions	Q9HCE9	Gene names	TMEM16H, KIAA1623
Domain Architecture	No domain graphic available
Description	Transmembrane protein 16H.

USF2_MOUSE
θ value	2.36792 (rank : 626)	NC score	0.016001 (rank : 997)
Query Neighborhood Hits	872	Target Neighborhood Hits	173	Shared Neighborhood Hits	22
SwissProt Accessions	Q64705, Q3UIL2, Q8VE59	Gene names	Usf2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (Major late transcription factor 2).

AA2AR_MOUSE
θ value	3.0926 (rank : 627)	NC score	-0.014778 (rank : 1142)
Query Neighborhood Hits	872	Target Neighborhood Hits	883	Shared Neighborhood Hits	3
SwissProt Accessions	Q60613	Gene names	Adora2a
Domain Architecture
Description	Adenosine A2a receptor.

ACK1_HUMAN
θ value	3.0926 (rank : 628)	NC score	0.020241 (rank : 973)
Query Neighborhood Hits	872	Target Neighborhood Hits	1140	Shared Neighborhood Hits	202
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

ACK1_MOUSE
θ value	3.0926 (rank : 629)	NC score	0.018123 (rank : 988)
Query Neighborhood Hits	872	Target Neighborhood Hits	1080	Shared Neighborhood Hits	186
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

ARHGG_MOUSE
θ value	3.0926 (rank : 630)	NC score	0.094033 (rank : 362)
Query Neighborhood Hits	872	Target Neighborhood Hits	152	Shared Neighborhood Hits	62
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

BC11B_HUMAN
θ value	3.0926 (rank : 631)	NC score	0.003698 (rank : 1101)
Query Neighborhood Hits	872	Target Neighborhood Hits	761	Shared Neighborhood Hits	48
SwissProt Accessions	Q9C0K0, Q9H162	Gene names	BCL11B, CTIP2, RIT1
Domain Architecture	No domain graphic available
Description	B-cell lymphoma/leukemia 11B (B-cell CLL/lymphoma 11B) (Radiation- induced tumor suppressor gene 1 protein) (hRit1) (COUP-TF-interacting protein 2).

CC040_HUMAN
θ value	3.0926 (rank : 632)	NC score	0.021624 (rank : 961)
Query Neighborhood Hits	872	Target Neighborhood Hits	23	Shared Neighborhood Hits	7
SwissProt Accessions	Q6UXB0, Q8TA84	Gene names	C3orf40
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf40 precursor.

CO4A1_HUMAN
θ value	3.0926 (rank : 633)	NC score	0.088838 (rank : 403)
Query Neighborhood Hits	872	Target Neighborhood Hits	425	Shared Neighborhood Hits	156
SwissProt Accessions	P02462	Gene names	COL4A1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

COBA2_MOUSE
θ value	3.0926 (rank : 634)	NC score	0.090459 (rank : 394)
Query Neighborhood Hits	872	Target Neighborhood Hits	501	Shared Neighborhood Hits	162
SwissProt Accessions	Q64739, Q61432, Q9Z1W0	Gene names	Col11a2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

COIA1_MOUSE
θ value	3.0926 (rank : 635)	NC score	0.083405 (rank : 448)
Query Neighborhood Hits	872	Target Neighborhood Hits	481	Shared Neighborhood Hits	155
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

CTTB2_HUMAN
θ value	3.0926 (rank : 636)	NC score	0.025959 (rank : 923)
Query Neighborhood Hits	872	Target Neighborhood Hits	1061	Shared Neighborhood Hits	90
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

DMRTD_MOUSE
θ value	3.0926 (rank : 637)	NC score	0.051898 (rank : 755)
Query Neighborhood Hits	872	Target Neighborhood Hits	72	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CGW9	Gene names	Dmrtc2, Dmrt7
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2 (Doublesex- and mab-3-related transcription factor 7).

DYR1B_MOUSE
θ value	3.0926 (rank : 638)	NC score	-0.002941 (rank : 1132)
Query Neighborhood Hits	872	Target Neighborhood Hits	799	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Z188	Gene names	Dyrk1b
Domain Architecture
Description	Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1).

EFNB3_MOUSE
θ value	3.0926 (rank : 639)	NC score	0.011337 (rank : 1043)
Query Neighborhood Hits	872	Target Neighborhood Hits	50	Shared Neighborhood Hits	11
SwissProt Accessions	O35393	Gene names	Efnb3
Domain Architecture
Description	Ephrin-B3 precursor.

EFS_HUMAN
θ value	3.0926 (rank : 640)	NC score	0.164272 (rank : 163)
Query Neighborhood Hits	872	Target Neighborhood Hits	348	Shared Neighborhood Hits	192
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

FBLI1_MOUSE
θ value	3.0926 (rank : 641)	NC score	0.021297 (rank : 964)
Query Neighborhood Hits	872	Target Neighborhood Hits	228	Shared Neighborhood Hits	38
SwissProt Accessions	Q71FD7, Q99J35	Gene names	Fblim1, Cal
Domain Architecture	No domain graphic available
Description	Filamin-binding LIM protein 1 (CSX-associated LIM).

FCRLA_HUMAN
θ value	3.0926 (rank : 642)	NC score	0.011713 (rank : 1041)
Query Neighborhood Hits	872	Target Neighborhood Hits	135	Shared Neighborhood Hits	23
SwissProt Accessions	Q7L513, Q5VXA1, Q5VXA2, Q5VXA3, Q5VXB0, Q8NEW4, Q8WXH3, Q96PC6, Q96PJ0, Q96PJ1, Q96PJ2, Q96PJ4, Q9BR57	Gene names	FCRLA, FCRL, FCRL1, FCRLM1, FCRX, FREB
Domain Architecture	No domain graphic available
Description	Fc receptor-like and mucin-like 1 precursor (Fc receptor-like A) (Fc receptor homolog expressed in B-cells) (Fc receptor-related protein X) (FcRX) (Fc receptor-like protein).

FHOD1_MOUSE
θ value	3.0926 (rank : 643)	NC score	0.071446 (rank : 533)
Query Neighborhood Hits	872	Target Neighborhood Hits	217	Shared Neighborhood Hits	93
SwissProt Accessions	Q6P9Q4, Q8BMK2	Gene names	Fhod1, Fhos1
Domain Architecture	No domain graphic available
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

FOSL1_HUMAN
θ value	3.0926 (rank : 644)	NC score	0.011091 (rank : 1047)
Query Neighborhood Hits	872	Target Neighborhood Hits	112	Shared Neighborhood Hits	14
SwissProt Accessions	P15407	Gene names	FOSL1, FRA1
Domain Architecture
Description	Fos-related antigen 1 (FRA-1).

FOXH1_HUMAN
θ value	3.0926 (rank : 645)	NC score	0.044148 (rank : 809)
Query Neighborhood Hits	872	Target Neighborhood Hits	258	Shared Neighborhood Hits	123
SwissProt Accessions	O75593	Gene names	FOXH1, FAST1, FAST2
Domain Architecture
Description	Forkhead box protein H1 (Forkhead activin signal transducer 1) (Fast- 1) (hFAST-1) (Forkhead activin signal transducer 2) (Fast-2).

GPNMB_MOUSE
θ value	3.0926 (rank : 646)	NC score	0.013327 (rank : 1019)
Query Neighborhood Hits	872	Target Neighborhood Hits	40	Shared Neighborhood Hits	14
SwissProt Accessions	Q99P91, Q8BVV9, Q8BXL4, Q9QXA0	Gene names	Gpnmb, Dchil, Nmb
Domain Architecture	No domain graphic available
Description	Transmembrane glycoprotein NMB precursor (Dendritic cell-associated transmembrane protein) (DC-HIL).

HCN2_HUMAN
θ value	3.0926 (rank : 647)	NC score	0.058437 (rank : 667)
Query Neighborhood Hits	872	Target Neighborhood Hits	369	Shared Neighborhood Hits	141
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

HME1_HUMAN
θ value	3.0926 (rank : 648)	NC score	0.018490 (rank : 982)
Query Neighborhood Hits	872	Target Neighborhood Hits	384	Shared Neighborhood Hits	46
SwissProt Accessions	Q05925	Gene names	EN1
Domain Architecture
Description	Homeobox protein engrailed-1 (Hu-En-1).

HXB4_MOUSE
θ value	3.0926 (rank : 649)	NC score	0.012575 (rank : 1031)
Query Neighborhood Hits	872	Target Neighborhood Hits	375	Shared Neighborhood Hits	49
SwissProt Accessions	P10284, Q3UZB4, Q4VBG0	Gene names	Hoxb4, Hox-2.6, Hoxb-4
Domain Architecture
Description	Homeobox protein Hox-B4 (Hox-2.6).

IF4G1_HUMAN
θ value	3.0926 (rank : 650)	NC score	0.043107 (rank : 816)
Query Neighborhood Hits	872	Target Neighborhood Hits	347	Shared Neighborhood Hits	110
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

JUND_MOUSE
θ value	3.0926 (rank : 651)	NC score	0.009740 (rank : 1058)
Query Neighborhood Hits	872	Target Neighborhood Hits	134	Shared Neighborhood Hits	16
SwissProt Accessions	P15066	Gene names	Jund, Jun-d, Jund1
Domain Architecture
Description	Transcription factor jun-D.

LNP_MOUSE
θ value	3.0926 (rank : 652)	NC score	0.032726 (rank : 875)
Query Neighborhood Hits	872	Target Neighborhood Hits	83	Shared Neighborhood Hits	25
SwissProt Accessions	Q7TQ95, Q69ZC5, Q6PAQ1, Q6PEN8	Gene names	Lnp, Kiaa1715, Uln
Domain Architecture	No domain graphic available
Description	Protein lunapark (Protein ulnaless).

LOXL1_HUMAN
θ value	3.0926 (rank : 653)	NC score	0.017018 (rank : 995)
Query Neighborhood Hits	872	Target Neighborhood Hits	31	Shared Neighborhood Hits	9
SwissProt Accessions	Q08397, Q96BW7	Gene names	LOXL1, LOXL
Domain Architecture
Description	Lysyl oxidase homolog 1 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 1) (LOL).

MEF2C_MOUSE
θ value	3.0926 (rank : 654)	NC score	0.028336 (rank : 907)
Query Neighborhood Hits	872	Target Neighborhood Hits	92	Shared Neighborhood Hits	31
SwissProt Accessions	Q8CFN5, Q8R0H1, Q9D7L0, Q9QW20	Gene names	Mef2c
Domain Architecture	No domain graphic available
Description	Myocyte-specific enhancer factor 2C.

MYLK2_HUMAN
θ value	3.0926 (rank : 655)	NC score	-0.000234 (rank : 1123)
Query Neighborhood Hits	872	Target Neighborhood Hits	920	Shared Neighborhood Hits	78
SwissProt Accessions	Q9H1R3, Q96I84	Gene names	MYLK2
Domain Architecture
Description	Myosin light chain kinase 2, skeletal/cardiac muscle (EC 2.7.11.18) (MLCK2).

PO121_MOUSE
θ value	3.0926 (rank : 656)	NC score	0.071135 (rank : 535)
Query Neighborhood Hits	872	Target Neighborhood Hits	345	Shared Neighborhood Hits	92
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

PRR13_HUMAN
θ value	3.0926 (rank : 657)	NC score	0.084281 (rank : 443)
Query Neighborhood Hits	872	Target Neighborhood Hits	105	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

RBBP6_HUMAN
θ value	3.0926 (rank : 658)	NC score	0.031809 (rank : 884)
Query Neighborhood Hits	872	Target Neighborhood Hits	1135	Shared Neighborhood Hits	107
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RBBP6_MOUSE
θ value	3.0926 (rank : 659)	NC score	0.031535 (rank : 887)
Query Neighborhood Hits	872	Target Neighborhood Hits	1014	Shared Neighborhood Hits	105
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

RIMB1_MOUSE
θ value	3.0926 (rank : 660)	NC score	0.068730 (rank : 556)
Query Neighborhood Hits	872	Target Neighborhood Hits	1376	Shared Neighborhood Hits	231
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RUSC2_MOUSE
θ value	3.0926 (rank : 661)	NC score	0.103756 (rank : 325)
Query Neighborhood Hits	872	Target Neighborhood Hits	305	Shared Neighborhood Hits	142
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

SREC2_HUMAN
θ value	3.0926 (rank : 662)	NC score	0.023957 (rank : 937)
Query Neighborhood Hits	872	Target Neighborhood Hits	645	Shared Neighborhood Hits	92
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

TBCD3_HUMAN
θ value	3.0926 (rank : 663)	NC score	0.008209 (rank : 1071)
Query Neighborhood Hits	872	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IZP1, Q9H0B9, Q9UDD4	Gene names	TBC1D3, PRC17
Domain Architecture
Description	TBC1 domain family member 3 (Rab GTPase-activating protein PRC17) (Prostate cancer gene 17 protein) (TRE17 alpha protein).

TCRG1_MOUSE
θ value	3.0926 (rank : 664)	NC score	0.078397 (rank : 482)
Query Neighborhood Hits	872	Target Neighborhood Hits	947	Shared Neighborhood Hits	128
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

TRIP6_HUMAN
θ value	3.0926 (rank : 665)	NC score	0.023356 (rank : 941)
Query Neighborhood Hits	872	Target Neighborhood Hits	228	Shared Neighborhood Hits	48
SwissProt Accessions	Q15654, O15170, O15275, Q9BTB2, Q9UNT4	Gene names	TRIP6, OIP1
Domain Architecture
Description	Thyroid receptor-interacting protein 6 (TRIP6) (OPA-interacting protein 1) (Zyxin-related protein 1) (ZRP-1).

TULP4_MOUSE
θ value	3.0926 (rank : 666)	NC score	0.026702 (rank : 916)
Query Neighborhood Hits	872	Target Neighborhood Hits	247	Shared Neighborhood Hits	62
SwissProt Accessions	Q9JIL5, Q8CA75, Q922C2	Gene names	Tulp4, Tusp
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

ZEP2_HUMAN
θ value	3.0926 (rank : 667)	NC score	0.012245 (rank : 1035)
Query Neighborhood Hits	872	Target Neighborhood Hits	937	Shared Neighborhood Hits	102
SwissProt Accessions	P31629, Q02646, Q5THT5, Q9NS05	Gene names	HIVEP2
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 (HIV- EP2) (MHC-binding protein 2) (MBP-2).

ZN385_HUMAN
θ value	3.0926 (rank : 668)	NC score	0.165333 (rank : 160)
Query Neighborhood Hits	872	Target Neighborhood Hits	614	Shared Neighborhood Hits	270
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

ABI3_MOUSE
θ value	4.03905 (rank : 669)	NC score	0.161753 (rank : 167)
Query Neighborhood Hits	872	Target Neighborhood Hits	227	Shared Neighborhood Hits	134
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

ADA19_HUMAN
θ value	4.03905 (rank : 670)	NC score	0.014575 (rank : 1009)
Query Neighborhood Hits	872	Target Neighborhood Hits	381	Shared Neighborhood Hits	85
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

ANR40_HUMAN
θ value	4.03905 (rank : 671)	NC score	0.022353 (rank : 950)
Query Neighborhood Hits	872	Target Neighborhood Hits	224	Shared Neighborhood Hits	34
SwissProt Accessions	Q6AI12, Q96E32	Gene names	ANKRD40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

ATS20_MOUSE
θ value	4.03905 (rank : 672)	NC score	0.000588 (rank : 1117)
Query Neighborhood Hits	872	Target Neighborhood Hits	225	Shared Neighborhood Hits	12
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

BAG3_MOUSE
θ value	4.03905 (rank : 673)	NC score	0.122131 (rank : 257)
Query Neighborhood Hits	872	Target Neighborhood Hits	513	Shared Neighborhood Hits	212
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

BI2L1_HUMAN
θ value	4.03905 (rank : 674)	NC score	0.054657 (rank : 718)
Query Neighborhood Hits	872	Target Neighborhood Hits	156	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UHR4, Q75L21, Q75L22, Q96CV4, Q9Y2M8	Gene names	BAIAP2L1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

BSN_HUMAN
θ value	4.03905 (rank : 675)	NC score	0.140146 (rank : 214)
Query Neighborhood Hits	872	Target Neighborhood Hits	1537	Shared Neighborhood Hits	362
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CI079_HUMAN
θ value	4.03905 (rank : 676)	NC score	0.076578 (rank : 496)
Query Neighborhood Hits	872	Target Neighborhood Hits	288	Shared Neighborhood Hits	93
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

CSTF2_MOUSE
θ value	4.03905 (rank : 677)	NC score	0.036567 (rank : 856)
Query Neighborhood Hits	872	Target Neighborhood Hits	255	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BIQ5, Q8K1Y6, Q9ERC2	Gene names	Cstf2
Domain Architecture	No domain graphic available
Description	Cleavage stimulation factor 64 kDa subunit (CSTF 64 kDa subunit) (CF-1 64 kDa subunit) (CstF-64).

DDEF2_HUMAN
θ value	4.03905 (rank : 678)	NC score	0.140744 (rank : 210)
Query Neighborhood Hits	872	Target Neighborhood Hits	599	Shared Neighborhood Hits	169
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DUS8_MOUSE
θ value	4.03905 (rank : 679)	NC score	0.010537 (rank : 1053)
Query Neighborhood Hits	872	Target Neighborhood Hits	119	Shared Neighborhood Hits	23
SwissProt Accessions	O09112	Gene names	Dusp8, Nttp1
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Neuronal tyrosine threonine phosphatase 1).

EDEM1_MOUSE
θ value	4.03905 (rank : 680)	NC score	0.005589 (rank : 1092)
Query Neighborhood Hits	872	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q925U4	Gene names	Edem1, Edem
Domain Architecture
Description	ER degradation-enhancing alpha-mannosidase-like 1.

FOXN1_MOUSE
θ value	4.03905 (rank : 681)	NC score	0.047343 (rank : 793)
Query Neighborhood Hits	872	Target Neighborhood Hits	300	Shared Neighborhood Hits	126
SwissProt Accessions	Q61575	Gene names	Foxn1, Fkh19, Hfh11, Whn
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/forkhead homolog 11) (HFH-11).

HXA3_HUMAN
θ value	4.03905 (rank : 682)	NC score	0.026370 (rank : 920)
Query Neighborhood Hits	872	Target Neighborhood Hits	535	Shared Neighborhood Hits	109
SwissProt Accessions	O43365	Gene names	HOXA3, HOX1E
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1E).

IRX3_MOUSE
θ value	4.03905 (rank : 683)	NC score	0.023261 (rank : 942)
Query Neighborhood Hits	872	Target Neighborhood Hits	303	Shared Neighborhood Hits	46
SwissProt Accessions	P81067	Gene names	Irx3, Irxb1
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-3 (Iroquois homeobox protein 3) (Homeodomain protein IRXB1).

IRX5_HUMAN
θ value	4.03905 (rank : 684)	NC score	0.033998 (rank : 867)
Query Neighborhood Hits	872	Target Neighborhood Hits	362	Shared Neighborhood Hits	80
SwissProt Accessions	P78411, P78416, Q7Z2E1	Gene names	IRX5, IRX2A, IRXB2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-5 (Iroquois homeobox protein 5) (Homeodomain protein IRXB2) (IRX-2A).

MAST4_HUMAN
θ value	4.03905 (rank : 685)	NC score	0.032807 (rank : 874)
Query Neighborhood Hits	872	Target Neighborhood Hits	1804	Shared Neighborhood Hits	305
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

MATK_HUMAN
θ value	4.03905 (rank : 686)	NC score	0.014213 (rank : 1010)
Query Neighborhood Hits	872	Target Neighborhood Hits	954	Shared Neighborhood Hits	76
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

NUAK1_MOUSE
θ value	4.03905 (rank : 687)	NC score	-0.003187 (rank : 1135)
Query Neighborhood Hits	872	Target Neighborhood Hits	881	Shared Neighborhood Hits	46
SwissProt Accessions	Q641K5, Q6I6D6, Q8CGE1	Gene names	Nuak1, Kiaa0537
Domain Architecture	No domain graphic available
Description	NUAK family SNF1-like kinase 1 (EC 2.7.11.1).

NUP53_MOUSE
θ value	4.03905 (rank : 688)	NC score	0.056628 (rank : 685)
Query Neighborhood Hits	872	Target Neighborhood Hits	94	Shared Neighborhood Hits	54
SwissProt Accessions	Q8R4R6, Q9D7J2	Gene names	Nup35, Mp44, Nup53
Domain Architecture	No domain graphic available
Description	Nucleoporin NUP53 (Nuclear pore complex protein Nup53) (Nucleoporin Nup35) (35 kDa nucleoporin) (Mitotic phosphoprotein 44) (MP-44).

OST4_HUMAN
θ value	4.03905 (rank : 689)	NC score	0.011328 (rank : 1044)
Query Neighborhood Hits	872	Target Neighborhood Hits	95	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y661, Q5QI42, Q8NDC2	Gene names	HS3ST4, 3OST4
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 4 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4) (Heparan sulfate 3-O-sulfotransferase 4) (h3-OST-4).

PDC6I_MOUSE
θ value	4.03905 (rank : 690)	NC score	0.061000 (rank : 628)
Query Neighborhood Hits	872	Target Neighborhood Hits	275	Shared Neighborhood Hits	87
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

PHLB1_HUMAN
θ value	4.03905 (rank : 691)	NC score	0.072893 (rank : 520)
Query Neighborhood Hits	872	Target Neighborhood Hits	1038	Shared Neighborhood Hits	204
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

RFIP5_MOUSE
θ value	4.03905 (rank : 692)	NC score	0.018520 (rank : 980)
Query Neighborhood Hits	872	Target Neighborhood Hits	126	Shared Neighborhood Hits	31
SwissProt Accessions	Q8R361	Gene names	Rab11fip5, D6Ertd32e, Rip11
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 5 (Rab11-FIP5) (Rab11-interacting protein Rip11).

RGL2_HUMAN
θ value	4.03905 (rank : 693)	NC score	0.017914 (rank : 990)
Query Neighborhood Hits	872	Target Neighborhood Hits	45	Shared Neighborhood Hits	15
SwissProt Accessions	O15211, Q9Y3F3	Gene names	RGL2, RAB2L
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator-like 2 (RalGDS-like factor) (RAS-associated protein RAB2L).

SASH1_HUMAN
θ value	4.03905 (rank : 694)	NC score	0.066123 (rank : 577)
Query Neighborhood Hits	872	Target Neighborhood Hits	292	Shared Neighborhood Hits	137
SwissProt Accessions	O94885, Q8TAI0, Q9H7R7	Gene names	SASH1, KIAA0790, PEPE1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat- containing protein).

SH3G1_MOUSE
θ value	4.03905 (rank : 695)	NC score	0.158677 (rank : 173)
Query Neighborhood Hits	872	Target Neighborhood Hits	291	Shared Neighborhood Hits	124
SwissProt Accessions	Q62419	Gene names	Sh3gl1, Sh3d2b
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (SH3p8).

STF1_HUMAN
θ value	4.03905 (rank : 696)	NC score	0.010569 (rank : 1052)
Query Neighborhood Hits	872	Target Neighborhood Hits	132	Shared Neighborhood Hits	25
SwissProt Accessions	Q13285, O15196	Gene names	NR5A1, AD4BP, FTZF1, SF1
Domain Architecture
Description	Steroidogenic factor 1 (STF-1) (SF-1) (Adrenal 4-binding protein) (Steroid hormone receptor Ad4BP) (Fushi tarazu factor homolog 1).

SYNP2_MOUSE
θ value	4.03905 (rank : 697)	NC score	0.037270 (rank : 849)
Query Neighborhood Hits	872	Target Neighborhood Hits	252	Shared Neighborhood Hits	57
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

TARSH_HUMAN
θ value	4.03905 (rank : 698)	NC score	0.151457 (rank : 191)
Query Neighborhood Hits	872	Target Neighborhood Hits	768	Shared Neighborhood Hits	261
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

TAU_MOUSE
θ value	4.03905 (rank : 699)	NC score	0.087305 (rank : 414)
Query Neighborhood Hits	872	Target Neighborhood Hits	502	Shared Neighborhood Hits	163
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TCRG1_HUMAN
θ value	4.03905 (rank : 700)	NC score	0.072816 (rank : 522)
Query Neighborhood Hits	872	Target Neighborhood Hits	929	Shared Neighborhood Hits	117
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TEAD3_HUMAN
θ value	4.03905 (rank : 701)	NC score	0.005216 (rank : 1095)
Query Neighborhood Hits	872	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q99594, O95910, Q8N6Y4	Gene names	TEAD3, TEF5
Domain Architecture
Description	Transcriptional enhancer factor TEF-5 (TEA domain family member 3) (TEAD-3) (DTEF-1).

TESK1_MOUSE
θ value	4.03905 (rank : 702)	NC score	-0.002667 (rank : 1129)
Query Neighborhood Hits	872	Target Neighborhood Hits	862	Shared Neighborhood Hits	51
SwissProt Accessions	O70146, O70147	Gene names	Tesk1
Domain Architecture
Description	Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein kinase 1).

TIF1G_MOUSE
θ value	4.03905 (rank : 703)	NC score	0.026641 (rank : 917)
Query Neighborhood Hits	872	Target Neighborhood Hits	498	Shared Neighborhood Hits	94
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

WASP_HUMAN
θ value	4.03905 (rank : 704)	NC score	0.071090 (rank : 536)
Query Neighborhood Hits	872	Target Neighborhood Hits	195	Shared Neighborhood Hits	86
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

ZIM10_MOUSE
θ value	4.03905 (rank : 705)	NC score	0.128779 (rank : 242)
Query Neighborhood Hits	872	Target Neighborhood Hits	430	Shared Neighborhood Hits	232
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ATOH1_HUMAN
θ value	5.27518 (rank : 706)	NC score	0.007443 (rank : 1078)
Query Neighborhood Hits	872	Target Neighborhood Hits	97	Shared Neighborhood Hits	5
SwissProt Accessions	Q92858	Gene names	ATOH1, ATH1
Domain Architecture
Description	Atonal protein homolog 1 (Helix-loop-helix protein hATH-1).

CAP1_MOUSE
θ value	5.27518 (rank : 707)	NC score	0.010058 (rank : 1056)
Query Neighborhood Hits	872	Target Neighborhood Hits	46	Shared Neighborhood Hits	17
SwissProt Accessions	P40124	Gene names	Cap1, Cap
Domain Architecture
Description	Adenylyl cyclase-associated protein 1 (CAP 1).

CECR6_HUMAN
θ value	5.27518 (rank : 708)	NC score	0.013942 (rank : 1014)
Query Neighborhood Hits	872	Target Neighborhood Hits	23	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BXQ6	Gene names	CECR6
Domain Architecture	No domain graphic available
Description	Cat eye syndrome critical region protein 6.

CMTA2_HUMAN
θ value	5.27518 (rank : 709)	NC score	0.030556 (rank : 888)
Query Neighborhood Hits	872	Target Neighborhood Hits	199	Shared Neighborhood Hits	37
SwissProt Accessions	O94983, Q7Z6M8, Q8N3V0, Q8NDG4, Q96G17	Gene names	CAMTA2, KIAA0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

COBA1_MOUSE
θ value	5.27518 (rank : 710)	NC score	0.092873 (rank : 375)
Query Neighborhood Hits	872	Target Neighborhood Hits	487	Shared Neighborhood Hits	155
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

DCAK1_HUMAN
θ value	5.27518 (rank : 711)	NC score	-0.004519 (rank : 1136)
Query Neighborhood Hits	872	Target Neighborhood Hits	877	Shared Neighborhood Hits	40
SwissProt Accessions	O15075	Gene names	DCAMKL1, KIAA0369
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 1).

DIAP2_MOUSE
θ value	5.27518 (rank : 712)	NC score	0.062699 (rank : 609)
Query Neighborhood Hits	872	Target Neighborhood Hits	260	Shared Neighborhood Hits	67
SwissProt Accessions	O70566, Q8C2G8	Gene names	Diaph2, Diap2
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2) (mDia3).

DIAP3_MOUSE
θ value	5.27518 (rank : 713)	NC score	0.054051 (rank : 729)
Query Neighborhood Hits	872	Target Neighborhood Hits	221	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Z207	Gene names	Diaph3, Diap3
Domain Architecture
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3) (mDIA2) (p134mDIA2).

DMRTD_HUMAN
θ value	5.27518 (rank : 714)	NC score	0.094018 (rank : 363)
Query Neighborhood Hits	872	Target Neighborhood Hits	216	Shared Neighborhood Hits	125
SwissProt Accessions	Q8IXT2, Q8N6Q2, Q96M39, Q96SD4	Gene names	DMRTC2
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2.

DOK3_HUMAN
θ value	5.27518 (rank : 715)	NC score	0.018047 (rank : 989)
Query Neighborhood Hits	872	Target Neighborhood Hits	60	Shared Neighborhood Hits	18
SwissProt Accessions	Q7L591, Q8N864, Q9BQB3, Q9H666	Gene names	DOK3
Domain Architecture	No domain graphic available
Description	Docking protein 3 (Downstream of tyrosine kinase 3).

DYNA_MOUSE
θ value	5.27518 (rank : 716)	NC score	0.008567 (rank : 1069)
Query Neighborhood Hits	872	Target Neighborhood Hits	1084	Shared Neighborhood Hits	75
SwissProt Accessions	O08788	Gene names	Dctn1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued).

FOXJ3_HUMAN
θ value	5.27518 (rank : 717)	NC score	0.014917 (rank : 1003)
Query Neighborhood Hits	872	Target Neighborhood Hits	177	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UPW0, Q9NSS7	Gene names	FOXJ3, KIAA1041
Domain Architecture
Description	Forkhead box protein J3.

FOXO1_MOUSE
θ value	5.27518 (rank : 718)	NC score	0.010984 (rank : 1048)
Query Neighborhood Hits	872	Target Neighborhood Hits	118	Shared Neighborhood Hits	24
SwissProt Accessions	Q9R1E0	Gene names	Foxo1a, Fkhr, Foxo1
Domain Architecture
Description	Forkhead box protein O1A (Forkhead in rhabdomyosarcoma).

FUBP1_HUMAN
θ value	5.27518 (rank : 719)	NC score	0.037070 (rank : 852)
Query Neighborhood Hits	872	Target Neighborhood Hits	136	Shared Neighborhood Hits	58
SwissProt Accessions	Q96AE4, Q12828	Gene names	FUBP1
Domain Architecture
Description	Far upstream element-binding protein 1 (FUSE-binding protein 1) (FBP) (DNA helicase V) (HDH V).

FUBP1_MOUSE
θ value	5.27518 (rank : 720)	NC score	0.037209 (rank : 851)
Query Neighborhood Hits	872	Target Neighborhood Hits	144	Shared Neighborhood Hits	61
SwissProt Accessions	Q91WJ8, Q8C0Y8	Gene names	Fubp1, D3Ertd330e
Domain Architecture
Description	Far upstream element-binding protein 1 (FUSE-binding protein 1) (FBP).

FZD8_HUMAN
θ value	5.27518 (rank : 721)	NC score	0.000690 (rank : 1116)
Query Neighborhood Hits	872	Target Neighborhood Hits	88	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H461	Gene names	FZD8
Domain Architecture
Description	Frizzled-8 precursor (Fz-8) (hFz8).

GGA3_HUMAN
θ value	5.27518 (rank : 722)	NC score	0.026708 (rank : 915)
Query Neighborhood Hits	872	Target Neighborhood Hits	127	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NZ52, Q15017, Q6IS16, Q9UJY3	Gene names	GGA3, KIAA0154
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

GGA3_MOUSE
θ value	5.27518 (rank : 723)	NC score	0.031926 (rank : 883)
Query Neighborhood Hits	872	Target Neighborhood Hits	148	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BMI3, Q80U71	Gene names	Gga3, Kiaa0154
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

GHR_HUMAN
θ value	5.27518 (rank : 724)	NC score	0.008829 (rank : 1065)
Query Neighborhood Hits	872	Target Neighborhood Hits	57	Shared Neighborhood Hits	8
SwissProt Accessions	P10912, Q9HCX2	Gene names	GHR
Domain Architecture
Description	Growth hormone receptor precursor (GH receptor) (Somatotropin receptor) [Contains: Growth hormone-binding protein (GH-binding protein) (GHBP) (Serum-binding protein)].

GP156_MOUSE
θ value	5.27518 (rank : 725)	NC score	0.012043 (rank : 1037)
Query Neighborhood Hits	872	Target Neighborhood Hits	95	Shared Neighborhood Hits	24
SwissProt Accessions	Q6PCP7, Q8K452	Gene names	Gpr156, Gababl
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor).

LARP4_MOUSE
θ value	5.27518 (rank : 726)	NC score	0.059577 (rank : 647)
Query Neighborhood Hits	872	Target Neighborhood Hits	260	Shared Neighborhood Hits	106
SwissProt Accessions	Q8BWW4, Q3UR69	Gene names	Larp4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

MICA2_HUMAN
θ value	5.27518 (rank : 727)	NC score	0.007764 (rank : 1075)
Query Neighborhood Hits	872	Target Neighborhood Hits	174	Shared Neighborhood Hits	22
SwissProt Accessions	O94851, Q7Z3A8	Gene names	MICAL2, KIAA0750
Domain Architecture
Description	Protein MICAL-2.

OGFR_MOUSE
θ value	5.27518 (rank : 728)	NC score	0.120570 (rank : 260)
Query Neighborhood Hits	872	Target Neighborhood Hits	584	Shared Neighborhood Hits	168
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

PG12B_MOUSE
θ value	5.27518 (rank : 729)	NC score	0.008783 (rank : 1067)
Query Neighborhood Hits	872	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q99P27	Gene names	Pla2g12b, Pla2g13
Domain Architecture
Description	Group XIIB secretory phospholipase A2-like protein precursor (Group XIII secretory phospholipase A2-like protein) (GXIII sPLA2-like) (GXIIB).

PLS1_HUMAN
θ value	5.27518 (rank : 730)	NC score	0.006784 (rank : 1079)
Query Neighborhood Hits	872	Target Neighborhood Hits	35	Shared Neighborhood Hits	8
SwissProt Accessions	O15162	Gene names	PLSCR1
Domain Architecture
Description	Phospholipid scramblase 1 (PL scramblase 1) (Ca(2+)-dependent phospholipid scramblase 1) (Erythrocyte phospholipid scramblase) (MmTRA1b).

PLXB1_HUMAN
θ value	5.27518 (rank : 731)	NC score	0.033941 (rank : 868)
Query Neighborhood Hits	872	Target Neighborhood Hits	360	Shared Neighborhood Hits	126
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

PP1RA_MOUSE
θ value	5.27518 (rank : 732)	NC score	0.049884 (rank : 782)
Query Neighborhood Hits	872	Target Neighborhood Hits	175	Shared Neighborhood Hits	62
SwissProt Accessions	Q80W00, Q811B6, Q8C6T7, Q8K2U8	Gene names	Ppp1r10, Cat53
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 1 regulatory subunit 10 (MHC class I region proline-rich protein CAT53).

PRB4S_HUMAN
θ value	5.27518 (rank : 733)	NC score	0.112377 (rank : 293)
Query Neighborhood Hits	872	Target Neighborhood Hits	330	Shared Neighborhood Hits	120
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

PS1C2_HUMAN
θ value	5.27518 (rank : 734)	NC score	0.041240 (rank : 825)
Query Neighborhood Hits	872	Target Neighborhood Hits	66	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UIG4	Gene names	PSORS1C2, C6orf17, SPR1
Domain Architecture	No domain graphic available
Description	Psoriasis susceptibility 1 candidate gene 2 protein precursor (SPR1 protein).

REPS1_MOUSE
θ value	5.27518 (rank : 735)	NC score	0.035717 (rank : 859)
Query Neighborhood Hits	872	Target Neighborhood Hits	204	Shared Neighborhood Hits	41
SwissProt Accessions	O54916, Q8C9J9, Q99LR8	Gene names	Reps1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

SAPS1_HUMAN
θ value	5.27518 (rank : 736)	NC score	0.146711 (rank : 200)
Query Neighborhood Hits	872	Target Neighborhood Hits	704	Shared Neighborhood Hits	299
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

SEZ6L_HUMAN
θ value	5.27518 (rank : 737)	NC score	0.024074 (rank : 936)
Query Neighborhood Hits	872	Target Neighborhood Hits	289	Shared Neighborhood Hits	80
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

SGIP1_HUMAN
θ value	5.27518 (rank : 738)	NC score	0.054578 (rank : 721)
Query Neighborhood Hits	872	Target Neighborhood Hits	198	Shared Neighborhood Hits	83
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SIN3A_MOUSE
θ value	5.27518 (rank : 739)	NC score	0.029785 (rank : 891)
Query Neighborhood Hits	872	Target Neighborhood Hits	169	Shared Neighborhood Hits	56
SwissProt Accessions	Q60520, Q60820, Q62139, Q62140, Q7TPU8, Q7TSZ2	Gene names	Sin3a
Domain Architecture
Description	Paired amphipathic helix protein Sin3a (Transcriptional corepressor Sin3a) (Histone deacetylase complex subunit Sin3a).

SPR2G_HUMAN
θ value	5.27518 (rank : 740)	NC score	0.020580 (rank : 970)
Query Neighborhood Hits	872	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BYE4	Gene names	SPRR2G
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G (SPR-2G).

SYFB_MOUSE
θ value	5.27518 (rank : 741)	NC score	0.020824 (rank : 968)
Query Neighborhood Hits	872	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WUA2	Gene names	Farslb, Farsb, Farsl, Frsb
Domain Architecture
Description	Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) (Phenylalanine-- tRNA ligase beta chain) (PheRS).

SYNP2_HUMAN
θ value	5.27518 (rank : 742)	NC score	0.063282 (rank : 604)
Query Neighborhood Hits	872	Target Neighborhood Hits	323	Shared Neighborhood Hits	107
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

TOIP2_HUMAN
θ value	5.27518 (rank : 743)	NC score	0.010968 (rank : 1049)
Query Neighborhood Hits	872	Target Neighborhood Hits	102	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NFQ8	Gene names	TOR1AIP2, LULL1
Domain Architecture	No domain graphic available
Description	Torsin-1A-interacting protein 2 (Lumenal domain-like LAP1).

TRML1_MOUSE
θ value	5.27518 (rank : 744)	NC score	0.014598 (rank : 1008)
Query Neighborhood Hits	872	Target Neighborhood Hits	44	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K558, Q9D3N6	Gene names	Treml1, Tlt1
Domain Architecture	No domain graphic available
Description	Trem-like transcript 1 protein precursor (TLT-1) (Triggering receptor expressed on myeloid cells-like protein 1).

UBP31_HUMAN
θ value	5.27518 (rank : 745)	NC score	0.019519 (rank : 975)
Query Neighborhood Hits	872	Target Neighborhood Hits	293	Shared Neighborhood Hits	51
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

VAX1_HUMAN
θ value	5.27518 (rank : 746)	NC score	0.010445 (rank : 1054)
Query Neighborhood Hits	872	Target Neighborhood Hits	355	Shared Neighborhood Hits	30
SwissProt Accessions	Q5SQQ9, Q6ZSX0	Gene names	VAX1
Domain Architecture	No domain graphic available
Description	Ventral anterior homeobox 1.

WASP_MOUSE
θ value	5.27518 (rank : 747)	NC score	0.073288 (rank : 518)
Query Neighborhood Hits	872	Target Neighborhood Hits	223	Shared Neighborhood Hits	91
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

ZN318_MOUSE
θ value	5.27518 (rank : 748)	NC score	0.028634 (rank : 899)
Query Neighborhood Hits	872	Target Neighborhood Hits	642	Shared Neighborhood Hits	84
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

3BP2_HUMAN
θ value	6.88961 (rank : 749)	NC score	0.086324 (rank : 422)
Query Neighborhood Hits	872	Target Neighborhood Hits	296	Shared Neighborhood Hits	122
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

ABCA4_MOUSE
θ value	6.88961 (rank : 750)	NC score	-0.001170 (rank : 1124)
Query Neighborhood Hits	872	Target Neighborhood Hits	126	Shared Neighborhood Hits	10
SwissProt Accessions	O35600	Gene names	Abca4, Abcr
Domain Architecture
Description	Retinal-specific ATP-binding cassette transporter (ATP-binding cassette sub-family A member 4) (RIM ABC transporter) (RIM protein) (RmP).

AF17_HUMAN
θ value	6.88961 (rank : 751)	NC score	0.015397 (rank : 1000)
Query Neighborhood Hits	872	Target Neighborhood Hits	230	Shared Neighborhood Hits	47
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

AFF2_HUMAN
θ value	6.88961 (rank : 752)	NC score	0.021844 (rank : 957)
Query Neighborhood Hits	872	Target Neighborhood Hits	218	Shared Neighborhood Hits	53
SwissProt Accessions	P51816, O43786, O60215, P78407, Q13521, Q14323, Q9UNA5	Gene names	AFF2, FMR2, OX19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation 2 protein) (Protein FMR-2) (FMR2P) (Protein Ox19) (Fragile X E mental retardation syndrome protein).

ALK_MOUSE
θ value	6.88961 (rank : 753)	NC score	-0.002976 (rank : 1133)
Query Neighborhood Hits	872	Target Neighborhood Hits	811	Shared Neighborhood Hits	40
SwissProt Accessions	P97793	Gene names	Alk
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

ARTN_HUMAN
θ value	6.88961 (rank : 754)	NC score	0.011261 (rank : 1046)
Query Neighborhood Hits	872	Target Neighborhood Hits	42	Shared Neighborhood Hits	10
SwissProt Accessions	Q5T4W7, O95441, O96030, Q6P6A3	Gene names	ARTN, EVN
Domain Architecture	No domain graphic available
Description	Artemin precursor (Enovin) (Neublastin).

ATF7_HUMAN
θ value	6.88961 (rank : 755)	NC score	0.021013 (rank : 966)
Query Neighborhood Hits	872	Target Neighborhood Hits	333	Shared Neighborhood Hits	60
SwissProt Accessions	P17544, Q13814	Gene names	ATF7, ATFA
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

BIN1_HUMAN
θ value	6.88961 (rank : 756)	NC score	0.082914 (rank : 452)
Query Neighborhood Hits	872	Target Neighborhood Hits	335	Shared Neighborhood Hits	140
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

C2TA_HUMAN
θ value	6.88961 (rank : 757)	NC score	0.028525 (rank : 902)
Query Neighborhood Hits	872	Target Neighborhood Hits	190	Shared Neighborhood Hits	62
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

CAR10_HUMAN
θ value	6.88961 (rank : 758)	NC score	0.010126 (rank : 1055)
Query Neighborhood Hits	872	Target Neighborhood Hits	569	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BWT7, Q14CQ8, Q5TFG6, Q9UGR5, Q9UGR6, Q9Y3H0	Gene names	CARD10, CARMA3
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (CARD-containing MAGUK protein 3) (Carma 3).

CASL_HUMAN
θ value	6.88961 (rank : 759)	NC score	0.143547 (rank : 206)
Query Neighborhood Hits	872	Target Neighborhood Hits	259	Shared Neighborhood Hits	139
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

CEP68_MOUSE
θ value	6.88961 (rank : 760)	NC score	0.037025 (rank : 853)
Query Neighborhood Hits	872	Target Neighborhood Hits	62	Shared Neighborhood Hits	10
SwissProt Accessions	Q8C0D9, Q3US49, Q5SW85, Q8R2V0	Gene names	Cep68
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 68 kDa (Cep68 protein).

CNOT3_HUMAN
θ value	6.88961 (rank : 761)	NC score	0.049609 (rank : 783)
Query Neighborhood Hits	872	Target Neighborhood Hits	425	Shared Neighborhood Hits	89
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CO8A2_HUMAN
θ value	6.88961 (rank : 762)	NC score	0.079619 (rank : 473)
Query Neighborhood Hits	872	Target Neighborhood Hits	299	Shared Neighborhood Hits	125
SwissProt Accessions	P25067, Q8TEJ5	Gene names	COL8A2
Domain Architecture
Description	Collagen alpha-2(VIII) chain precursor (Endothelial collagen).

COAA1_HUMAN
θ value	6.88961 (rank : 763)	NC score	0.077289 (rank : 492)
Query Neighborhood Hits	872	Target Neighborhood Hits	316	Shared Neighborhood Hits	114
SwissProt Accessions	Q03692	Gene names	COL10A1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

CUTL2_HUMAN
θ value	6.88961 (rank : 764)	NC score	0.030100 (rank : 890)
Query Neighborhood Hits	872	Target Neighborhood Hits	906	Shared Neighborhood Hits	139
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

DBX1_MOUSE
θ value	6.88961 (rank : 765)	NC score	0.011860 (rank : 1038)
Query Neighborhood Hits	872	Target Neighborhood Hits	346	Shared Neighborhood Hits	30
SwissProt Accessions	P52950	Gene names	Dbx1, Dbx
Domain Architecture
Description	Homeobox protein DBX1.

DIAP2_HUMAN
θ value	6.88961 (rank : 766)	NC score	0.061536 (rank : 623)
Query Neighborhood Hits	872	Target Neighborhood Hits	342	Shared Neighborhood Hits	70
SwissProt Accessions	O60879, O60878, Q8WX06, Q8WX48, Q9UJL2	Gene names	DIAPH2, DIA
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2).

DOK2_HUMAN
θ value	6.88961 (rank : 767)	NC score	0.012792 (rank : 1027)
Query Neighborhood Hits	872	Target Neighborhood Hits	46	Shared Neighborhood Hits	12
SwissProt Accessions	O60496	Gene names	DOK2
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)).

DVL1_MOUSE
θ value	6.88961 (rank : 768)	NC score	0.027053 (rank : 913)
Query Neighborhood Hits	872	Target Neighborhood Hits	146	Shared Neighborhood Hits	15
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

ETV4_MOUSE
θ value	6.88961 (rank : 769)	NC score	0.009707 (rank : 1059)
Query Neighborhood Hits	872	Target Neighborhood Hits	100	Shared Neighborhood Hits	23
SwissProt Accessions	P28322	Gene names	Etv4, Pea-3, Pea3
Domain Architecture
Description	ETS translocation variant 4 (Polyomavirus enhancer activator 3) (Protein PEA3).

FOXB2_MOUSE
θ value	6.88961 (rank : 770)	NC score	0.014164 (rank : 1012)
Query Neighborhood Hits	872	Target Neighborhood Hits	139	Shared Neighborhood Hits	37
SwissProt Accessions	Q64733	Gene names	Foxb2, Fkh4
Domain Architecture
Description	Forkhead box protein B2 (Transcription factor FKH-4).

FOXJ2_HUMAN
θ value	6.88961 (rank : 771)	NC score	0.029164 (rank : 896)
Query Neighborhood Hits	872	Target Neighborhood Hits	239	Shared Neighborhood Hits	88
SwissProt Accessions	Q9P0K8, Q96PS9, Q9NSN5	Gene names	FOXJ2, FHX
Domain Architecture
Description	Forkhead box protein J2 (Fork head homologous X).

FOXP4_HUMAN
θ value	6.88961 (rank : 772)	NC score	0.021370 (rank : 963)
Query Neighborhood Hits	872	Target Neighborhood Hits	246	Shared Neighborhood Hits	68
SwissProt Accessions	Q8IVH2, Q96E19	Gene names	FOXP4, FKHLA
Domain Architecture
Description	Forkhead box protein P4 (Fork head-related protein-like A).

FYB_HUMAN
θ value	6.88961 (rank : 773)	NC score	0.088608 (rank : 405)
Query Neighborhood Hits	872	Target Neighborhood Hits	379	Shared Neighborhood Hits	140
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

GLI3_HUMAN
θ value	6.88961 (rank : 774)	NC score	0.002482 (rank : 1110)
Query Neighborhood Hits	872	Target Neighborhood Hits	871	Shared Neighborhood Hits	82
SwissProt Accessions	P10071, O75219, Q9UDT5, Q9UJ39	Gene names	GLI3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI3.

GRIN1_HUMAN
θ value	6.88961 (rank : 775)	NC score	0.118935 (rank : 266)
Query Neighborhood Hits	872	Target Neighborhood Hits	681	Shared Neighborhood Hits	214
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

HSF1_MOUSE
θ value	6.88961 (rank : 776)	NC score	0.050064 (rank : 780)
Query Neighborhood Hits	872	Target Neighborhood Hits	267	Shared Neighborhood Hits	99
SwissProt Accessions	P38532, O70462	Gene names	Hsf1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

IF4G3_HUMAN
θ value	6.88961 (rank : 777)	NC score	0.013689 (rank : 1016)
Query Neighborhood Hits	872	Target Neighborhood Hits	247	Shared Neighborhood Hits	36
SwissProt Accessions	O43432, Q15597, Q8NEN1	Gene names	EIF4G3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

INVS_MOUSE
θ value	6.88961 (rank : 778)	NC score	0.036864 (rank : 855)
Query Neighborhood Hits	872	Target Neighborhood Hits	609	Shared Neighborhood Hits	126
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

K0999_MOUSE
θ value	6.88961 (rank : 779)	NC score	-0.002872 (rank : 1131)
Query Neighborhood Hits	872	Target Neighborhood Hits	931	Shared Neighborhood Hits	64
SwissProt Accessions	Q6P4S6, Q641L5, Q66JZ5, Q6ZQ09, Q8K075, Q9CYD5	Gene names	Kiaa0999
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase KIAA0999 (EC 2.7.11.1).

LSD1_MOUSE
θ value	6.88961 (rank : 780)	NC score	0.022095 (rank : 953)
Query Neighborhood Hits	872	Target Neighborhood Hits	224	Shared Neighborhood Hits	28
SwissProt Accessions	Q6ZQ88, Q6PB53, Q8VEA1	Gene names	Aof2, Kiaa0601, Lsd1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

LYN_MOUSE
θ value	6.88961 (rank : 781)	NC score	0.022082 (rank : 954)
Query Neighborhood Hits	872	Target Neighborhood Hits	1023	Shared Neighborhood Hits	127
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

MAVS_HUMAN
θ value	6.88961 (rank : 782)	NC score	0.064199 (rank : 597)
Query Neighborhood Hits	872	Target Neighborhood Hits	271	Shared Neighborhood Hits	97
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

MINT_HUMAN
θ value	6.88961 (rank : 783)	NC score	0.058859 (rank : 658)
Query Neighborhood Hits	872	Target Neighborhood Hits	1291	Shared Neighborhood Hits	193
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MN1_HUMAN
θ value	6.88961 (rank : 784)	NC score	0.056367 (rank : 689)
Query Neighborhood Hits	872	Target Neighborhood Hits	196	Shared Neighborhood Hits	71
SwissProt Accessions	Q10571	Gene names	MN1
Domain Architecture	No domain graphic available
Description	Probable tumor suppressor protein MN1.

PO6F1_MOUSE
θ value	6.88961 (rank : 785)	NC score	0.035218 (rank : 864)
Query Neighborhood Hits	872	Target Neighborhood Hits	581	Shared Neighborhood Hits	131
SwissProt Accessions	Q07916, Q91XK3	Gene names	Pou6f1, Emb
Domain Architecture
Description	POU domain, class 6, transcription factor 1 (Octamer-binding transcription factor EMB) (Transcription regulatory protein MCP-1).

PRRT3_HUMAN
θ value	6.88961 (rank : 786)	NC score	0.273840 (rank : 64)
Query Neighborhood Hits	872	Target Neighborhood Hits	998	Shared Neighborhood Hits	414
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

PTPRN_MOUSE
θ value	6.88961 (rank : 787)	NC score	0.024089 (rank : 935)
Query Neighborhood Hits	872	Target Neighborhood Hits	240	Shared Neighborhood Hits	82
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

RIN3_MOUSE
θ value	6.88961 (rank : 788)	NC score	0.040703 (rank : 827)
Query Neighborhood Hits	872	Target Neighborhood Hits	239	Shared Neighborhood Hits	83
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

SALL3_HUMAN
θ value	6.88961 (rank : 789)	NC score	0.014671 (rank : 1007)
Query Neighborhood Hits	872	Target Neighborhood Hits	1066	Shared Neighborhood Hits	165
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

SMN_HUMAN
θ value	6.88961 (rank : 790)	NC score	0.012876 (rank : 1024)
Query Neighborhood Hits	872	Target Neighborhood Hits	39	Shared Neighborhood Hits	8
SwissProt Accessions	Q16637, Q13119, Q96J51	Gene names	SMN1, SMN, SMNT
Domain Architecture
Description	Survival motor neuron protein (Component of gems 1) (Gemin-1).

SMR3B_HUMAN
θ value	6.88961 (rank : 791)	NC score	0.088096 (rank : 406)
Query Neighborhood Hits	872	Target Neighborhood Hits	46	Shared Neighborhood Hits	20
SwissProt Accessions	P02814, Q9UBN0, Q9UCT0	Gene names	SMR3B, PBII, PROL3
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog B precursor (Proline-rich protein 3) (Proline-rich peptide P-B) [Contains: Peptide P-A; Peptide D1A].

SNX18_HUMAN
θ value	6.88961 (rank : 792)	NC score	0.084876 (rank : 433)
Query Neighborhood Hits	872	Target Neighborhood Hits	207	Shared Neighborhood Hits	100
SwissProt Accessions	Q96RF0	Gene names	SNAG1, SNX18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

SPHK2_HUMAN
θ value	6.88961 (rank : 793)	NC score	0.010743 (rank : 1051)
Query Neighborhood Hits	872	Target Neighborhood Hits	81	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NRA0, Q9BRN1, Q9H0Q2, Q9NWU7	Gene names	SPHK2
Domain Architecture
Description	Sphingosine kinase 2 (EC 2.7.1.-) (SK 2) (SPK 2).

SPR2E_MOUSE
θ value	6.88961 (rank : 794)	NC score	0.018297 (rank : 984)
Query Neighborhood Hits	872	Target Neighborhood Hits	45	Shared Neighborhood Hits	9
SwissProt Accessions	O70556	Gene names	Sprr2e
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E.

SREC2_MOUSE
θ value	6.88961 (rank : 795)	NC score	0.018246 (rank : 986)
Query Neighborhood Hits	872	Target Neighborhood Hits	605	Shared Neighborhood Hits	74
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

TAF5_HUMAN
θ value	6.88961 (rank : 796)	NC score	-0.002414 (rank : 1127)
Query Neighborhood Hits	872	Target Neighborhood Hits	352	Shared Neighborhood Hits	15
SwissProt Accessions	Q15542, Q86UZ7, Q9Y4K5	Gene names	TAF5, TAF2D
Domain Architecture
Description	Transcription initiation factor TFIID subunit 5 (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100).

TS101_MOUSE
θ value	6.88961 (rank : 797)	NC score	0.011764 (rank : 1040)
Query Neighborhood Hits	872	Target Neighborhood Hits	312	Shared Neighborhood Hits	19
SwissProt Accessions	Q61187	Gene names	Tsg101
Domain Architecture
Description	Tumor susceptibility gene 101 protein.

TTBK1_HUMAN
θ value	6.88961 (rank : 798)	NC score	0.009060 (rank : 1062)
Query Neighborhood Hits	872	Target Neighborhood Hits	1058	Shared Neighborhood Hits	121
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

USH1C_MOUSE
θ value	6.88961 (rank : 799)	NC score	0.026927 (rank : 914)
Query Neighborhood Hits	872	Target Neighborhood Hits	557	Shared Neighborhood Hits	83
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

ZDH14_MOUSE
θ value	6.88961 (rank : 800)	NC score	0.004265 (rank : 1100)
Query Neighborhood Hits	872	Target Neighborhood Hits	67	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BQQ1, Q8BNR2, Q8CFN0	Gene names	Zdhhc14
Domain Architecture	No domain graphic available
Description	Probable palmitoyltransferase ZDHHC14 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 14) (DHHC-14) (NEW1 domain-containing protein) (NEW1CP).

ZIMP7_MOUSE
θ value	6.88961 (rank : 801)	NC score	0.161112 (rank : 168)
Query Neighborhood Hits	872	Target Neighborhood Hits	566	Shared Neighborhood Hits	295
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

ABI3_HUMAN
θ value	8.99809 (rank : 802)	NC score	0.156740 (rank : 180)
Query Neighborhood Hits	872	Target Neighborhood Hits	227	Shared Neighborhood Hits	124
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

APXL_HUMAN
θ value	8.99809 (rank : 803)	NC score	0.064538 (rank : 594)
Query Neighborhood Hits	872	Target Neighborhood Hits	553	Shared Neighborhood Hits	132
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

BAP1_HUMAN
θ value	8.99809 (rank : 804)	NC score	0.018513 (rank : 981)
Query Neighborhood Hits	872	Target Neighborhood Hits	106	Shared Neighborhood Hits	29
SwissProt Accessions	Q92560, Q6LEM0, Q7Z5E8	Gene names	BAP1, KIAA0272
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1- associated protein 1) (Cerebral protein 6).

BAP1_MOUSE
θ value	8.99809 (rank : 805)	NC score	0.017198 (rank : 993)
Query Neighborhood Hits	872	Target Neighborhood Hits	118	Shared Neighborhood Hits	33
SwissProt Accessions	Q99PU7, Q6ZQE6	Gene names	Bap1, Kiaa0272
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1- associated protein 1) (Ubiquitin C-terminal hydrolase X4) (UCH-X4).

C1QR1_HUMAN
θ value	8.99809 (rank : 806)	NC score	0.013269 (rank : 1021)
Query Neighborhood Hits	872	Target Neighborhood Hits	493	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

CCDC6_HUMAN
θ value	8.99809 (rank : 807)	NC score	0.012802 (rank : 1026)
Query Neighborhood Hits	872	Target Neighborhood Hits	723	Shared Neighborhood Hits	50
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

CELR3_HUMAN
θ value	8.99809 (rank : 808)	NC score	0.000455 (rank : 1119)
Query Neighborhood Hits	872	Target Neighborhood Hits	680	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

CELR3_MOUSE
θ value	8.99809 (rank : 809)	NC score	-0.001208 (rank : 1125)
Query Neighborhood Hits	872	Target Neighborhood Hits	687	Shared Neighborhood Hits	47
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

CEP41_HUMAN
θ value	8.99809 (rank : 810)	NC score	0.013615 (rank : 1018)
Query Neighborhood Hits	872	Target Neighborhood Hits	42	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BYV8, Q7Z496, Q86TM1, Q8NFU8, Q9H6A3, Q9NPV3	Gene names	TSGA14, CEP41
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 41 kDa (Cep41 protein) (Testis-specific gene A14 protein).

COFA1_MOUSE
θ value	8.99809 (rank : 811)	NC score	0.071658 (rank : 532)
Query Neighborhood Hits	872	Target Neighborhood Hits	305	Shared Neighborhood Hits	100
SwissProt Accessions	O35206, Q9EQD9	Gene names	Col15a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV)].

CSKP_HUMAN
θ value	8.99809 (rank : 812)	NC score	0.008194 (rank : 1073)
Query Neighborhood Hits	872	Target Neighborhood Hits	1022	Shared Neighborhood Hits	106
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

CSKP_MOUSE
θ value	8.99809 (rank : 813)	NC score	0.007572 (rank : 1077)
Query Neighborhood Hits	872	Target Neighborhood Hits	1027	Shared Neighborhood Hits	111
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

CSTF2_HUMAN
θ value	8.99809 (rank : 814)	NC score	0.048890 (rank : 786)
Query Neighborhood Hits	872	Target Neighborhood Hits	296	Shared Neighborhood Hits	69
SwissProt Accessions	P33240, Q5H951, Q6LA74, Q8N502	Gene names	CSTF2
Domain Architecture
Description	Cleavage stimulation factor 64 kDa subunit (CSTF 64 kDa subunit) (CF-1 64 kDa subunit) (CstF-64).

DAB2P_HUMAN
θ value	8.99809 (rank : 815)	NC score	0.005511 (rank : 1093)
Query Neighborhood Hits	872	Target Neighborhood Hits	303	Shared Neighborhood Hits	33
SwissProt Accessions	Q5VWQ8, Q8TDL2, Q96SE1, Q9C0C0	Gene names	DAB2IP, AF9Q34, AIP1, KIAA1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein) (DAB2 interaction protein) (ASK-interacting protein 1).

DEND_HUMAN
θ value	8.99809 (rank : 816)	NC score	0.018737 (rank : 979)
Query Neighborhood Hits	872	Target Neighborhood Hits	88	Shared Neighborhood Hits	24
SwissProt Accessions	O94850	Gene names	DDN, KIAA0749
Domain Architecture	No domain graphic available
Description	Dendrin.

DEND_MOUSE
θ value	8.99809 (rank : 817)	NC score	0.022849 (rank : 947)
Query Neighborhood Hits	872	Target Neighborhood Hits	75	Shared Neighborhood Hits	32
SwissProt Accessions	Q80TS7	Gene names	Ddn, Kiaa0749
Domain Architecture	No domain graphic available
Description	Dendrin.

DLX4_MOUSE
θ value	8.99809 (rank : 818)	NC score	0.013627 (rank : 1017)
Query Neighborhood Hits	872	Target Neighborhood Hits	352	Shared Neighborhood Hits	36
SwissProt Accessions	P70436, Q3UM51, Q8R4I3	Gene names	Dlx4, Dlx7
Domain Architecture
Description	Homeobox protein DLX-4 (DLX-7).

DOK7_MOUSE
θ value	8.99809 (rank : 819)	NC score	0.063575 (rank : 601)
Query Neighborhood Hits	872	Target Neighborhood Hits	169	Shared Neighborhood Hits	82
SwissProt Accessions	Q18PE0, Q3TCZ6, Q5FW70, Q8C8U7	Gene names	Dok7
Domain Architecture	No domain graphic available
Description	Protein Dok-7 (Downstream of tyrosine kinase 7).

DVL2_MOUSE
θ value	8.99809 (rank : 820)	NC score	0.033599 (rank : 870)
Query Neighborhood Hits	872	Target Neighborhood Hits	233	Shared Neighborhood Hits	56
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

EFNB3_HUMAN
θ value	8.99809 (rank : 821)	NC score	0.008988 (rank : 1063)
Query Neighborhood Hits	872	Target Neighborhood Hits	48	Shared Neighborhood Hits	12
SwissProt Accessions	Q15768, O00680, Q8TBH7, Q92875	Gene names	EFNB3, EPLG8, LERK8
Domain Architecture
Description	Ephrin-B3 precursor (EPH-related receptor tyrosine kinase ligand 8) (LERK-8) (EPH-related receptor transmembrane ligand ELK-L3).

EFS_MOUSE
θ value	8.99809 (rank : 822)	NC score	0.184311 (rank : 128)
Query Neighborhood Hits	872	Target Neighborhood Hits	389	Shared Neighborhood Hits	215
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

ETV3_MOUSE
θ value	8.99809 (rank : 823)	NC score	0.009997 (rank : 1057)
Query Neighborhood Hits	872	Target Neighborhood Hits	128	Shared Neighborhood Hits	33
SwissProt Accessions	Q8R4Z4, Q9QZW1	Gene names	Etv3, Mets, Pe1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

FOG1_MOUSE
θ value	8.99809 (rank : 824)	NC score	0.039353 (rank : 837)
Query Neighborhood Hits	872	Target Neighborhood Hits	1237	Shared Neighborhood Hits	250
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

GATA5_MOUSE
θ value	8.99809 (rank : 825)	NC score	0.002847 (rank : 1106)
Query Neighborhood Hits	872	Target Neighborhood Hits	51	Shared Neighborhood Hits	11
SwissProt Accessions	P97489	Gene names	Gata5
Domain Architecture
Description	Transcription factor GATA-5 (GATA-binding factor 5).

GDF6_HUMAN
θ value	8.99809 (rank : 826)	NC score	0.000476 (rank : 1118)
Query Neighborhood Hits	872	Target Neighborhood Hits	76	Shared Neighborhood Hits	6
SwissProt Accessions	Q6KF10, Q6PI58	Gene names	GDF6, GDF16
Domain Architecture	No domain graphic available
Description	Growth/differentiation factor 6 precursor (GDF-6) (Growth/differentiation factor 16).

GP152_MOUSE
θ value	8.99809 (rank : 827)	NC score	0.020244 (rank : 972)
Query Neighborhood Hits	872	Target Neighborhood Hits	607	Shared Neighborhood Hits	102
SwissProt Accessions	Q8BXS7	Gene names	Gpr152
Domain Architecture
Description	Probable G-protein coupled receptor 152.

HCN2_MOUSE
θ value	8.99809 (rank : 828)	NC score	0.043806 (rank : 812)
Query Neighborhood Hits	872	Target Neighborhood Hits	278	Shared Neighborhood Hits	91
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

ICAL_HUMAN
θ value	8.99809 (rank : 829)	NC score	0.022372 (rank : 949)
Query Neighborhood Hits	872	Target Neighborhood Hits	275	Shared Neighborhood Hits	40
SwissProt Accessions	P20810, O95360, Q96D08, Q9H1Z5	Gene names	CAST
Domain Architecture
Description	Calpastatin (Calpain inhibitor) (Sperm BS-17 component).

IF35_MOUSE
θ value	8.99809 (rank : 830)	NC score	0.045630 (rank : 801)
Query Neighborhood Hits	872	Target Neighborhood Hits	210	Shared Neighborhood Hits	77
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

INSM1_MOUSE
θ value	8.99809 (rank : 831)	NC score	-0.001856 (rank : 1126)
Query Neighborhood Hits	872	Target Neighborhood Hits	678	Shared Neighborhood Hits	36
SwissProt Accessions	Q63ZV0, Q9Z113	Gene names	Insm1, Ia1
Domain Architecture	No domain graphic available
Description	Insulinoma-associated protein 1 (Zinc finger protein IA-1).

IP3KB_HUMAN
θ value	8.99809 (rank : 832)	NC score	0.015605 (rank : 999)
Query Neighborhood Hits	872	Target Neighborhood Hits	124	Shared Neighborhood Hits	42
SwissProt Accessions	P27987, Q5VWL9, Q5VWM0, Q96BZ2, Q96JS1, Q9UH47	Gene names	ITPKB
Domain Architecture
Description	Inositol-trisphosphate 3-kinase B (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase B) (IP3K B) (IP3 3-kinase B) (IP3K-B).

IWS1_MOUSE
θ value	8.99809 (rank : 833)	NC score	0.060618 (rank : 634)
Query Neighborhood Hits	872	Target Neighborhood Hits	1258	Shared Neighborhood Hits	183
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

JUND_HUMAN
θ value	8.99809 (rank : 834)	NC score	0.008724 (rank : 1068)
Query Neighborhood Hits	872	Target Neighborhood Hits	122	Shared Neighborhood Hits	14
SwissProt Accessions	P17535	Gene names	JUND
Domain Architecture
Description	Transcription factor jun-D.

KBTBB_HUMAN
θ value	8.99809 (rank : 835)	NC score	0.003109 (rank : 1104)
Query Neighborhood Hits	872	Target Neighborhood Hits	195	Shared Neighborhood Hits	21
SwissProt Accessions	O94819	Gene names	KBTBD11, KIAA0711, KLHDC7C
Domain Architecture	No domain graphic available
Description	Kelch repeat and BTB domain-containing protein 11 (Kelch domain- containing protein 7B).

KCNC3_HUMAN
θ value	8.99809 (rank : 836)	NC score	0.005661 (rank : 1091)
Query Neighborhood Hits	872	Target Neighborhood Hits	256	Shared Neighborhood Hits	68
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KLF16_HUMAN
θ value	8.99809 (rank : 837)	NC score	0.000065 (rank : 1121)
Query Neighborhood Hits	872	Target Neighborhood Hits	737	Shared Neighborhood Hits	51
SwissProt Accessions	Q9BXK1	Gene names	KLF16, BTEB4, NSLP2
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 16 (Transcription factor BTEB4) (Basic transcription element-binding protein 4) (BTE-binding protein 4) (Novel Sp1-like zinc finger transcription factor 2) (Transcription factor NSLP2).

LEUK_HUMAN
θ value	8.99809 (rank : 838)	NC score	0.047509 (rank : 791)
Query Neighborhood Hits	872	Target Neighborhood Hits	213	Shared Neighborhood Hits	61
SwissProt Accessions	P16150	Gene names	SPN, CD43
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Galactoglycoprotein) (GALGP) (CD43 antigen).

LPP_HUMAN
θ value	8.99809 (rank : 839)	NC score	0.157274 (rank : 177)
Query Neighborhood Hits	872	Target Neighborhood Hits	775	Shared Neighborhood Hits	308
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

LSD1_HUMAN
θ value	8.99809 (rank : 840)	NC score	0.065068 (rank : 588)
Query Neighborhood Hits	872	Target Neighborhood Hits	455	Shared Neighborhood Hits	149
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

LYN_HUMAN
θ value	8.99809 (rank : 841)	NC score	0.022299 (rank : 951)
Query Neighborhood Hits	872	Target Neighborhood Hits	1022	Shared Neighborhood Hits	130
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

M3K14_MOUSE
θ value	8.99809 (rank : 842)	NC score	0.000380 (rank : 1120)
Query Neighborhood Hits	872	Target Neighborhood Hits	889	Shared Neighborhood Hits	66
SwissProt Accessions	Q9WUL6	Gene names	Map3k14, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF- kappa beta-inducing kinase) (Serine/threonine-protein kinase NIK).

MCM3A_HUMAN
θ value	8.99809 (rank : 843)	NC score	0.008201 (rank : 1072)
Query Neighborhood Hits	872	Target Neighborhood Hits	86	Shared Neighborhood Hits	15
SwissProt Accessions	O60318, Q9UMT4	Gene names	MCM3AP, GANP, KIAA0572, MAP80
Domain Architecture
Description	80 kDa MCM3-associated protein (GANP protein).

NACAM_MOUSE
θ value	8.99809 (rank : 844)	NC score	0.212397 (rank : 93)
Query Neighborhood Hits	872	Target Neighborhood Hits	1866	Shared Neighborhood Hits	472
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NCF1_HUMAN
θ value	8.99809 (rank : 845)	NC score	0.151005 (rank : 193)
Query Neighborhood Hits	872	Target Neighborhood Hits	198	Shared Neighborhood Hits	112
SwissProt Accessions	P14598, O43842, Q2PP07, Q9BU90, Q9BXI7, Q9BXI8, Q9UDV9, Q9UMU2	Gene names	NCF1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDa autosomal chronic granulomatous disease protein) (NOXO2).

NCF4_MOUSE
θ value	8.99809 (rank : 846)	NC score	0.172246 (rank : 147)
Query Neighborhood Hits	872	Target Neighborhood Hits	177	Shared Neighborhood Hits	109
SwissProt Accessions	P97369	Gene names	Ncf4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

NCOA6_MOUSE
θ value	8.99809 (rank : 847)	NC score	0.196350 (rank : 112)
Query Neighborhood Hits	872	Target Neighborhood Hits	1076	Shared Neighborhood Hits	376
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

NCOR1_HUMAN
θ value	8.99809 (rank : 848)	NC score	0.032302 (rank : 881)
Query Neighborhood Hits	872	Target Neighborhood Hits	577	Shared Neighborhood Hits	95
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

NKX28_HUMAN
θ value	8.99809 (rank : 849)	NC score	0.007683 (rank : 1076)
Query Neighborhood Hits	872	Target Neighborhood Hits	352	Shared Neighborhood Hits	29
SwissProt Accessions	O15522	Gene names	NKX2-8, NKX-2.8, NKX2G, NKX2H
Domain Architecture
Description	Homeobox protein Nkx-2.8 (Homeobox protein NK-2 homolog H).

OST2_MOUSE
θ value	8.99809 (rank : 850)	NC score	0.002918 (rank : 1105)
Query Neighborhood Hits	872	Target Neighborhood Hits	48	Shared Neighborhood Hits	9
SwissProt Accessions	Q673U1, Q8BLP1, Q8C055	Gene names	Hs3st2, 3ost2
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 2 (EC 2.8.2.29) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2) (Heparan sulfate 3-O-sulfotransferase 2).

PAK4_MOUSE
θ value	8.99809 (rank : 851)	NC score	0.003560 (rank : 1103)
Query Neighborhood Hits	872	Target Neighborhood Hits	1098	Shared Neighborhood Hits	132
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

PCD15_MOUSE
θ value	8.99809 (rank : 852)	NC score	0.001426 (rank : 1114)
Query Neighborhood Hits	872	Target Neighborhood Hits	262	Shared Neighborhood Hits	41
SwissProt Accessions	Q99PJ1	Gene names	Pcdh15
Domain Architecture
Description	Protocadherin-15 precursor.

PRGC1_HUMAN
θ value	8.99809 (rank : 853)	NC score	0.009094 (rank : 1061)
Query Neighborhood Hits	872	Target Neighborhood Hits	157	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UBK2, Q9UN32	Gene names	PPARGC1A, LEM6, PGC1, PGC1A, PPARGC1
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPAR gamma coactivator 1-alpha) (PPARGC-1-alpha) (PGC-1-alpha) (Ligand effect modulator 6).

PSMF1_MOUSE
θ value	8.99809 (rank : 854)	NC score	0.054222 (rank : 725)
Query Neighborhood Hits	872	Target Neighborhood Hits	85	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BHL8, Q8C0G9	Gene names	Psmf1
Domain Architecture	No domain graphic available
Description	Proteasome inhibitor PI31 subunit.

RC3H1_HUMAN
θ value	8.99809 (rank : 855)	NC score	0.073383 (rank : 517)
Query Neighborhood Hits	872	Target Neighborhood Hits	433	Shared Neighborhood Hits	141
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

RGDSR_HUMAN
θ value	8.99809 (rank : 856)	NC score	0.021683 (rank : 959)
Query Neighborhood Hits	872	Target Neighborhood Hits	63	Shared Neighborhood Hits	26
SwissProt Accessions	Q8IZJ4	Gene names	RGR
Domain Architecture
Description	Ral-GDS-related protein (hRGR).

RP3A_MOUSE
θ value	8.99809 (rank : 857)	NC score	0.053525 (rank : 739)
Query Neighborhood Hits	872	Target Neighborhood Hits	510	Shared Neighborhood Hits	173
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

RRBP1_MOUSE
θ value	8.99809 (rank : 858)	NC score	0.038997 (rank : 843)
Query Neighborhood Hits	872	Target Neighborhood Hits	1650	Shared Neighborhood Hits	170
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

RTN4R_MOUSE
θ value	8.99809 (rank : 859)	NC score	-0.003062 (rank : 1134)
Query Neighborhood Hits	872	Target Neighborhood Hits	293	Shared Neighborhood Hits	32
SwissProt Accessions	Q99PI8, Q80WQ1	Gene names	Rtn4r, Nogor
Domain Architecture	No domain graphic available
Description	Reticulon-4 receptor precursor (Nogo receptor) (NgR) (Nogo-66 receptor).

SCAP_HUMAN
θ value	8.99809 (rank : 860)	NC score	0.027099 (rank : 912)
Query Neighborhood Hits	872	Target Neighborhood Hits	368	Shared Neighborhood Hits	92
SwissProt Accessions	Q12770, Q8N2E0, Q8WUA1	Gene names	SCAP, KIAA0199
Domain Architecture
Description	Sterol regulatory element-binding protein cleavage-activating protein (SREBP cleavage-activating protein) (SCAP).

SORC2_HUMAN
θ value	8.99809 (rank : 861)	NC score	0.005727 (rank : 1090)
Query Neighborhood Hits	872	Target Neighborhood Hits	66	Shared Neighborhood Hits	25
SwissProt Accessions	Q96PQ0, Q9P2L7	Gene names	SORCS2, KIAA1329
Domain Architecture
Description	VPS10 domain-containing receptor SorCS2 precursor.

SRRM2_HUMAN
θ value	8.99809 (rank : 862)	NC score	0.097245 (rank : 347)
Query Neighborhood Hits	872	Target Neighborhood Hits	1296	Shared Neighborhood Hits	229
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

ST5_HUMAN
θ value	8.99809 (rank : 863)	NC score	0.012299 (rank : 1034)
Query Neighborhood Hits	872	Target Neighborhood Hits	151	Shared Neighborhood Hits	36
SwissProt Accessions	P78524, P78523, Q16492, Q7KYY2, Q7KZ12, Q8NE12, Q9BQQ6	Gene names	ST5, DENND2B, HTS1
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (HeLa tumor suppression 1) (DENN domain-containing protein 2B).

SYP2L_MOUSE
θ value	8.99809 (rank : 864)	NC score	0.051498 (rank : 761)
Query Neighborhood Hits	872	Target Neighborhood Hits	289	Shared Neighborhood Hits	75
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

TAF5_MOUSE
θ value	8.99809 (rank : 865)	NC score	-0.002752 (rank : 1130)
Query Neighborhood Hits	872	Target Neighborhood Hits	366	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C092, Q8BTR2	Gene names	Taf5
Domain Architecture
Description	Transcription initiation factor TFIID subunit 5 (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100).

TFG_HUMAN
θ value	8.99809 (rank : 866)	NC score	0.046717 (rank : 797)
Query Neighborhood Hits	872	Target Neighborhood Hits	122	Shared Neighborhood Hits	44
SwissProt Accessions	Q92734, Q15656	Gene names	TFG
Domain Architecture
Description	Protein TFG (TRK-fused gene protein).

TMEPA_HUMAN
θ value	8.99809 (rank : 867)	NC score	0.012662 (rank : 1030)
Query Neighborhood Hits	872	Target Neighborhood Hits	46	Shared Neighborhood Hits	20
SwissProt Accessions	Q969W9, Q5TDR6, Q96B72, Q9UJD3	Gene names	TMEPAI, PMEPA1, STAG1
Domain Architecture
Description	Transmembrane prostate androgen-induced protein (Solid tumor- associated 1 protein).

TRIM7_MOUSE
θ value	8.99809 (rank : 868)	NC score	-0.005821 (rank : 1140)
Query Neighborhood Hits	872	Target Neighborhood Hits	358	Shared Neighborhood Hits	11
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

VASP_HUMAN
θ value	8.99809 (rank : 869)	NC score	0.064598 (rank : 592)
Query Neighborhood Hits	872	Target Neighborhood Hits	201	Shared Neighborhood Hits	81
SwissProt Accessions	P50552, Q6PIZ1, Q93035	Gene names	VASP
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

ZN414_HUMAN
θ value	8.99809 (rank : 870)	NC score	0.025546 (rank : 926)
Query Neighborhood Hits	872	Target Neighborhood Hits	548	Shared Neighborhood Hits	64
SwissProt Accessions	Q96IQ9	Gene names	ZNF414
Domain Architecture	No domain graphic available
Description	Zinc finger protein 414.

ZN541_HUMAN
θ value	8.99809 (rank : 871)	NC score	0.036279 (rank : 857)
Query Neighborhood Hits	872	Target Neighborhood Hits	203	Shared Neighborhood Hits	69
SwissProt Accessions	Q9H0D2, Q8NDK8	Gene names	ZNF541
Domain Architecture	No domain graphic available
Description	Zinc finger protein 541.

ZN687_HUMAN
θ value	8.99809 (rank : 872)	NC score	0.054667 (rank : 715)
Query Neighborhood Hits	872	Target Neighborhood Hits	1244	Shared Neighborhood Hits	322
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

AMPH_HUMAN
θ value	θ > 10 (rank : 873)	NC score	0.079355 (rank : 475)
Query Neighborhood Hits	872	Target Neighborhood Hits	455	Shared Neighborhood Hits	141
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

AMPH_MOUSE
θ value	θ > 10 (rank : 874)	NC score	0.062179 (rank : 619)
Query Neighborhood Hits	872	Target Neighborhood Hits	291	Shared Neighborhood Hits	90
SwissProt Accessions	Q7TQF7, Q8R1C4	Gene names	Amph, Amph1
Domain Architecture
Description	Amphiphysin.

ANK2_HUMAN
θ value	θ > 10 (rank : 875)	NC score	0.068587 (rank : 558)
Query Neighborhood Hits	872	Target Neighborhood Hits	1615	Shared Neighborhood Hits	300
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ANM2_HUMAN
θ value	θ > 10 (rank : 876)	NC score	0.091359 (rank : 382)
Query Neighborhood Hits	872	Target Neighborhood Hits	175	Shared Neighborhood Hits	97
SwissProt Accessions	P55345, P78350, Q9BW15, Q9UMC2	Gene names	PRMT2, HMT1, HRMT1L1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

ANM2_MOUSE
θ value	θ > 10 (rank : 877)	NC score	0.090468 (rank : 393)
Query Neighborhood Hits	872	Target Neighborhood Hits	175	Shared Neighborhood Hits	94
SwissProt Accessions	Q9R144	Gene names	Prmt2, Hrmt1l1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

ARFG3_HUMAN
θ value	θ > 10 (rank : 878)	NC score	0.050969 (rank : 771)
Query Neighborhood Hits	872	Target Neighborhood Hits	56	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NP61, Q9BSC6, Q9H9J0, Q9NT10, Q9NUP5, Q9Y4V3, Q9Y4V4	Gene names	ARFGAP3, ARFGAP1
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

ARFG3_MOUSE
θ value	θ > 10 (rank : 879)	NC score	0.051346 (rank : 764)
Query Neighborhood Hits	872	Target Neighborhood Hits	80	Shared Neighborhood Hits	13
SwissProt Accessions	Q9D8S3, Q99KN8	Gene names	Arfgap3
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

ARHG1_HUMAN
θ value	θ > 10 (rank : 880)	NC score	0.062562 (rank : 612)
Query Neighborhood Hits	872	Target Neighborhood Hits	176	Shared Neighborhood Hits	70
SwissProt Accessions	Q92888, O00513, Q8N4J4, Q96BF4, Q96F17, Q9BSB1	Gene names	ARHGEF1
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide exchange factor) (Sub1.5).

ARHG1_MOUSE
θ value	θ > 10 (rank : 881)	NC score	0.068797 (rank : 554)
Query Neighborhood Hits	872	Target Neighborhood Hits	266	Shared Neighborhood Hits	107
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

ARHG2_HUMAN
θ value	θ > 10 (rank : 882)	NC score	0.051760 (rank : 757)
Query Neighborhood Hits	872	Target Neighborhood Hits	142	Shared Neighborhood Hits	34
SwissProt Accessions	Q92974, O75142, Q15079	Gene names	ARHGEF2, KIAA0651, LFP40
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (GEF-H1 protein) (Proliferating cell nucleolar antigen p40).

ARHG2_MOUSE
θ value	θ > 10 (rank : 883)	NC score	0.050137 (rank : 779)
Query Neighborhood Hits	872	Target Neighborhood Hits	120	Shared Neighborhood Hits	30
SwissProt Accessions	Q60875, O09115	Gene names	Arhgef2, Lbcl1, Lfc
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (Lymphoid blast crisis- like 1) (LBC'S first cousin) (Oncogene LFC) (RHOBIN).

ARHG3_HUMAN
θ value	θ > 10 (rank : 884)	NC score	0.078398 (rank : 481)
Query Neighborhood Hits	872	Target Neighborhood Hits	82	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NR81, Q6NUN3, Q7Z4U2, Q7Z5T2, Q9H7T4	Gene names	ARHGEF3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3 (Exchange factor found in platelets and leukemic and neuronal tissues) (XPLN).

ARHG3_MOUSE
θ value	θ > 10 (rank : 885)	NC score	0.077826 (rank : 487)
Query Neighborhood Hits	872	Target Neighborhood Hits	85	Shared Neighborhood Hits	31
SwissProt Accessions	Q91X46, Q8CDM0, Q91VY4, Q99K14, Q9DC31	Gene names	Arhgef3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3.

ARHG5_HUMAN
θ value	θ > 10 (rank : 886)	NC score	0.092801 (rank : 376)
Query Neighborhood Hits	872	Target Neighborhood Hits	172	Shared Neighborhood Hits	80
SwissProt Accessions	Q12774	Gene names	ARHGEF5, TIM
Domain Architecture
Description	Rho guanine nucleotide exchange factor 5 (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (p60 TIM) (Transforming immortalized mammary oncogene).

ARHG8_HUMAN
θ value	θ > 10 (rank : 887)	NC score	0.076181 (rank : 502)
Query Neighborhood Hits	872	Target Neighborhood Hits	85	Shared Neighborhood Hits	30
SwissProt Accessions	Q7Z628, Q12773, Q96D82, Q99903, Q9UEN6	Gene names	NET1, ARHGEF8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (p65 Net1 proto- oncogene) (Rho guanine nucleotide exchange factor 8).

ARHG8_MOUSE
θ value	θ > 10 (rank : 888)	NC score	0.076355 (rank : 500)
Query Neighborhood Hits	872	Target Neighborhood Hits	79	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Z206, Q8C4I0, Q9Z1L7	Gene names	Net1, Arhgef8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (Rho guanine nucleotide exchange factor 8).

ARHGA_HUMAN
θ value	θ > 10 (rank : 889)	NC score	0.082597 (rank : 455)
Query Neighborhood Hits	872	Target Neighborhood Hits	187	Shared Neighborhood Hits	33
SwissProt Accessions	O15013, O14665, Q68D55, Q8IWD9, Q8IY77	Gene names	ARHGEF10, KIAA0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

ARHGA_MOUSE
θ value	θ > 10 (rank : 890)	NC score	0.083684 (rank : 446)
Query Neighborhood Hits	872	Target Neighborhood Hits	125	Shared Neighborhood Hits	34
SwissProt Accessions	Q8C033, Q5DU38, Q80VH8, Q8BW76, Q922S7	Gene names	Arhgef10, Kiaa0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

ARHGB_HUMAN
θ value	θ > 10 (rank : 891)	NC score	0.059311 (rank : 652)
Query Neighborhood Hits	872	Target Neighborhood Hits	375	Shared Neighborhood Hits	66
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

ARHGC_HUMAN
θ value	θ > 10 (rank : 892)	NC score	0.054985 (rank : 709)
Query Neighborhood Hits	872	Target Neighborhood Hits	351	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGC_MOUSE
θ value	θ > 10 (rank : 893)	NC score	0.053342 (rank : 740)
Query Neighborhood Hits	872	Target Neighborhood Hits	344	Shared Neighborhood Hits	53
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGF_HUMAN
θ value	θ > 10 (rank : 894)	NC score	0.082720 (rank : 454)
Query Neighborhood Hits	872	Target Neighborhood Hits	214	Shared Neighborhood Hits	84
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

ARHGG_HUMAN
θ value	θ > 10 (rank : 895)	NC score	0.087218 (rank : 415)
Query Neighborhood Hits	872	Target Neighborhood Hits	129	Shared Neighborhood Hits	50
SwissProt Accessions	Q5VV41, Q86TF0, Q99434	Gene names	ARHGEF16, NBR
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

ARMX2_MOUSE
θ value	θ > 10 (rank : 896)	NC score	0.069334 (rank : 549)
Query Neighborhood Hits	872	Target Neighborhood Hits	349	Shared Neighborhood Hits	164
SwissProt Accessions	Q6A058, Q9CXI9	Gene names	Armcx2, Kiaa0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2.

ATX1_MOUSE
θ value	θ > 10 (rank : 897)	NC score	0.068010 (rank : 562)
Query Neighborhood Hits	872	Target Neighborhood Hits	264	Shared Neighborhood Hits	112
SwissProt Accessions	P54254	Gene names	Atxn1, Sca1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).

ATX7_HUMAN
θ value	θ > 10 (rank : 898)	NC score	0.073482 (rank : 516)
Query Neighborhood Hits	872	Target Neighborhood Hits	351	Shared Neighborhood Hits	144
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

ATX7_MOUSE
θ value	θ > 10 (rank : 899)	NC score	0.084295 (rank : 442)
Query Neighborhood Hits	872	Target Neighborhood Hits	328	Shared Neighborhood Hits	163
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

BAG3_HUMAN
θ value	θ > 10 (rank : 900)	NC score	0.060492 (rank : 635)
Query Neighborhood Hits	872	Target Neighborhood Hits	314	Shared Neighborhood Hits	117
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

BASP_HUMAN
θ value	θ > 10 (rank : 901)	NC score	0.051432 (rank : 762)
Query Neighborhood Hits	872	Target Neighborhood Hits	321	Shared Neighborhood Hits	66
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BASP_MOUSE
θ value	θ > 10 (rank : 902)	NC score	0.058818 (rank : 662)
Query Neighborhood Hits	872	Target Neighborhood Hits	260	Shared Neighborhood Hits	56
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BAT3_HUMAN
θ value	θ > 10 (rank : 903)	NC score	0.116652 (rank : 278)
Query Neighborhood Hits	872	Target Neighborhood Hits	490	Shared Neighborhood Hits	222
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

BAZ2A_HUMAN
θ value	θ > 10 (rank : 904)	NC score	0.057975 (rank : 673)
Query Neighborhood Hits	872	Target Neighborhood Hits	780	Shared Neighborhood Hits	176
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

BLNK_MOUSE
θ value	θ > 10 (rank : 905)	NC score	0.065363 (rank : 587)
Query Neighborhood Hits	872	Target Neighborhood Hits	296	Shared Neighborhood Hits	107
SwissProt Accessions	Q9QUN3, O88504	Gene names	Blnk, Bash, Ly57, Slp65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65) (Lymphocyte antigen 57).

C1QA_HUMAN
θ value	θ > 10 (rank : 906)	NC score	0.051268 (rank : 766)
Query Neighborhood Hits	872	Target Neighborhood Hits	179	Shared Neighborhood Hits	63
SwissProt Accessions	P02745, Q5T963	Gene names	C1QA
Domain Architecture
Description	Complement C1q subcomponent subunit A precursor.

CABIN_HUMAN
θ value	θ > 10 (rank : 907)	NC score	0.098636 (rank : 337)
Query Neighborhood Hits	872	Target Neighborhood Hits	490	Shared Neighborhood Hits	187
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

CASC3_MOUSE
θ value	θ > 10 (rank : 908)	NC score	0.056295 (rank : 692)
Query Neighborhood Hits	872	Target Neighborhood Hits	333	Shared Neighborhood Hits	99
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

CASL_MOUSE
θ value	θ > 10 (rank : 909)	NC score	0.134634 (rank : 230)
Query Neighborhood Hits	872	Target Neighborhood Hits	225	Shared Neighborhood Hits	133
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

CD248_HUMAN
θ value	θ > 10 (rank : 910)	NC score	0.084382 (rank : 440)
Query Neighborhood Hits	872	Target Neighborhood Hits	679	Shared Neighborhood Hits	199
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD248_MOUSE
θ value	θ > 10 (rank : 911)	NC score	0.065437 (rank : 586)
Query Neighborhood Hits	872	Target Neighborhood Hits	578	Shared Neighborhood Hits	175
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD2_HUMAN
θ value	θ > 10 (rank : 912)	NC score	0.147432 (rank : 197)
Query Neighborhood Hits	872	Target Neighborhood Hits	504	Shared Neighborhood Hits	230
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

CDN1C_HUMAN
θ value	θ > 10 (rank : 913)	NC score	0.052877 (rank : 743)
Query Neighborhood Hits	872	Target Neighborhood Hits	168	Shared Neighborhood Hits	65
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

CECR2_HUMAN
θ value	θ > 10 (rank : 914)	NC score	0.147612 (rank : 196)
Query Neighborhood Hits	872	Target Neighborhood Hits	543	Shared Neighborhood Hits	254
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

CEL_HUMAN
θ value	θ > 10 (rank : 915)	NC score	0.191885 (rank : 120)
Query Neighborhood Hits	872	Target Neighborhood Hits	896	Shared Neighborhood Hits	387
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

CENA1_HUMAN
θ value	θ > 10 (rank : 916)	NC score	0.054592 (rank : 720)
Query Neighborhood Hits	872	Target Neighborhood Hits	87	Shared Neighborhood Hits	13
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

CENA2_HUMAN
θ value	θ > 10 (rank : 917)	NC score	0.055979 (rank : 697)
Query Neighborhood Hits	872	Target Neighborhood Hits	83	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

CENB1_HUMAN
θ value	θ > 10 (rank : 918)	NC score	0.080283 (rank : 466)
Query Neighborhood Hits	872	Target Neighborhood Hits	383	Shared Neighborhood Hits	41
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

CENB2_HUMAN
θ value	θ > 10 (rank : 919)	NC score	0.086433 (rank : 418)
Query Neighborhood Hits	872	Target Neighborhood Hits	425	Shared Neighborhood Hits	39
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

CENB5_HUMAN
θ value	θ > 10 (rank : 920)	NC score	0.085518 (rank : 429)
Query Neighborhood Hits	872	Target Neighborhood Hits	395	Shared Neighborhood Hits	37
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

CENG3_HUMAN
θ value	θ > 10 (rank : 921)	NC score	0.054182 (rank : 726)
Query Neighborhood Hits	872	Target Neighborhood Hits	455	Shared Neighborhood Hits	35
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CENG3_MOUSE
θ value	θ > 10 (rank : 922)	NC score	0.055183 (rank : 705)
Query Neighborhood Hits	872	Target Neighborhood Hits	467	Shared Neighborhood Hits	40
SwissProt Accessions	Q8VHH5, Q812F7	Gene names	Centg3, Agap3
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CGRE1_HUMAN
θ value	θ > 10 (rank : 923)	NC score	0.057825 (rank : 674)
Query Neighborhood Hits	872	Target Neighborhood Hits	354	Shared Neighborhood Hits	90
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

CIP4_HUMAN
θ value	θ > 10 (rank : 924)	NC score	0.066771 (rank : 571)
Query Neighborhood Hits	872	Target Neighborhood Hits	374	Shared Neighborhood Hits	49
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

CIZ1_HUMAN
θ value	θ > 10 (rank : 925)	NC score	0.052424 (rank : 749)
Query Neighborhood Hits	872	Target Neighborhood Hits	359	Shared Neighborhood Hits	87
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

CJ078_MOUSE
θ value	θ > 10 (rank : 926)	NC score	0.070061 (rank : 544)
Query Neighborhood Hits	872	Target Neighborhood Hits	559	Shared Neighborhood Hits	118
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

CJ108_HUMAN
θ value	θ > 10 (rank : 927)	NC score	0.099417 (rank : 334)
Query Neighborhood Hits	872	Target Neighborhood Hits	165	Shared Neighborhood Hits	98
SwissProt Accessions	Q8N8Z3	Gene names	C10orf108
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C10orf108.

CK024_HUMAN
θ value	θ > 10 (rank : 928)	NC score	0.108434 (rank : 306)
Query Neighborhood Hits	872	Target Neighborhood Hits	408	Shared Neighborhood Hits	156
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

CN155_HUMAN
θ value	θ > 10 (rank : 929)	NC score	0.056064 (rank : 696)
Query Neighborhood Hits	872	Target Neighborhood Hits	385	Shared Neighborhood Hits	79
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

CNOT3_MOUSE
θ value	θ > 10 (rank : 930)	NC score	0.053772 (rank : 735)
Query Neighborhood Hits	872	Target Neighborhood Hits	504	Shared Neighborhood Hits	116
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CO002_HUMAN
θ value	θ > 10 (rank : 931)	NC score	0.097011 (rank : 350)
Query Neighborhood Hits	872	Target Neighborhood Hits	387	Shared Neighborhood Hits	149
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

CO039_HUMAN
θ value	θ > 10 (rank : 932)	NC score	0.064612 (rank : 591)
Query Neighborhood Hits	872	Target Neighborhood Hits	264	Shared Neighborhood Hits	108
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

CO039_MOUSE
θ value	θ > 10 (rank : 933)	NC score	0.114124 (rank : 288)
Query Neighborhood Hits	872	Target Neighborhood Hits	445	Shared Neighborhood Hits	200
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

CO4A2_HUMAN
θ value	θ > 10 (rank : 934)	NC score	0.090662 (rank : 390)
Query Neighborhood Hits	872	Target Neighborhood Hits	454	Shared Neighborhood Hits	172
SwissProt Accessions	P08572	Gene names	COL4A2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

CO4A2_MOUSE
θ value	θ > 10 (rank : 935)	NC score	0.093597 (rank : 368)
Query Neighborhood Hits	872	Target Neighborhood Hits	492	Shared Neighborhood Hits	178
SwissProt Accessions	P08122, Q61375	Gene names	Col4a2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

CO4A6_HUMAN
θ value	θ > 10 (rank : 936)	NC score	0.077417 (rank : 490)
Query Neighborhood Hits	872	Target Neighborhood Hits	318	Shared Neighborhood Hits	110
SwissProt Accessions	Q14031, Q12823, Q14053, Q5JYH6, Q9NQM5, Q9NTX3, Q9UJ76, Q9UMG6, Q9Y4L4	Gene names	COL4A6
Domain Architecture
Description	Collagen alpha-6(IV) chain precursor.

CO5A2_HUMAN
θ value	θ > 10 (rank : 937)	NC score	0.125080 (rank : 251)
Query Neighborhood Hits	872	Target Neighborhood Hits	760	Shared Neighborhood Hits	247
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

CO6A1_HUMAN
θ value	θ > 10 (rank : 938)	NC score	0.056111 (rank : 694)
Query Neighborhood Hits	872	Target Neighborhood Hits	264	Shared Neighborhood Hits	78
SwissProt Accessions	P12109, O00117, O00118, Q14040, Q14041, Q16258	Gene names	COL6A1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

CO6A1_MOUSE
θ value	θ > 10 (rank : 939)	NC score	0.057441 (rank : 676)
Query Neighborhood Hits	872	Target Neighborhood Hits	241	Shared Neighborhood Hits	71
SwissProt Accessions	Q04857	Gene names	Col6a1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

CO6A2_HUMAN
θ value	θ > 10 (rank : 940)	NC score	0.053850 (rank : 734)
Query Neighborhood Hits	872	Target Neighborhood Hits	249	Shared Neighborhood Hits	79
SwissProt Accessions	P12110, Q13909, Q13910, Q13911, Q14049, Q16259, Q16597, Q9UML3	Gene names	COL6A2
Domain Architecture
Description	Collagen alpha-2(VI) chain precursor.

CO6A2_MOUSE
θ value	θ > 10 (rank : 941)	NC score	0.052990 (rank : 742)
Query Neighborhood Hits	872	Target Neighborhood Hits	260	Shared Neighborhood Hits	79
SwissProt Accessions	Q02788, Q05505	Gene names	Col6a2
Domain Architecture
Description	Collagen alpha-2(VI) chain precursor.

CO7A1_HUMAN
θ value	θ > 10 (rank : 942)	NC score	0.076919 (rank : 493)
Query Neighborhood Hits	872	Target Neighborhood Hits	807	Shared Neighborhood Hits	194
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

CO9A2_HUMAN
θ value	θ > 10 (rank : 943)	NC score	0.068261 (rank : 560)
Query Neighborhood Hits	872	Target Neighborhood Hits	261	Shared Neighborhood Hits	97
SwissProt Accessions	Q14055	Gene names	COL9A2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(IX) chain precursor.

CO9A2_MOUSE
θ value	θ > 10 (rank : 944)	NC score	0.076503 (rank : 497)
Query Neighborhood Hits	872	Target Neighborhood Hits	279	Shared Neighborhood Hits	102
SwissProt Accessions	Q07643	Gene names	Col9a2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(IX) chain precursor.

COHA1_HUMAN
θ value	θ > 10 (rank : 945)	NC score	0.076839 (rank : 494)
Query Neighborhood Hits	872	Target Neighborhood Hits	400	Shared Neighborhood Hits	132
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

COIA1_HUMAN
θ value	θ > 10 (rank : 946)	NC score	0.080197 (rank : 468)
Query Neighborhood Hits	872	Target Neighborhood Hits	447	Shared Neighborhood Hits	162
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

COJA1_HUMAN
θ value	θ > 10 (rank : 947)	NC score	0.076386 (rank : 498)
Query Neighborhood Hits	872	Target Neighborhood Hits	323	Shared Neighborhood Hits	115
SwissProt Accessions	Q14993, Q00559, Q05850, Q12885, Q13676, Q5JUF0, Q5T424, Q9H572, Q9NPZ2, Q9NQP2	Gene names	COL19A1
Domain Architecture
Description	Collagen alpha-1(XIX) chain precursor (Collagen alpha-1(Y) chain).

COLQ_HUMAN
θ value	θ > 10 (rank : 948)	NC score	0.054433 (rank : 722)
Query Neighborhood Hits	872	Target Neighborhood Hits	193	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y215, Q6DK18, Q6YH18, Q6YH19, Q6YH20, Q6YH21, Q9NP18, Q9NP19, Q9NP20, Q9NP21, Q9NP22, Q9NP23, Q9NP24, Q9UP88	Gene names	COLQ
Domain Architecture	No domain graphic available
Description	Acetylcholinesterase collagenic tail peptide precursor (AChE Q subunit) (Acetylcholinesterase-associated collagen).

CONA1_HUMAN
θ value	θ > 10 (rank : 949)	NC score	0.072282 (rank : 525)
Query Neighborhood Hits	872	Target Neighborhood Hits	281	Shared Neighborhood Hits	101
SwissProt Accessions	Q86Y22, Q8IVR4, Q9NT93	Gene names	COL23A1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

CONA1_MOUSE
θ value	θ > 10 (rank : 950)	NC score	0.069132 (rank : 550)
Query Neighborhood Hits	872	Target Neighborhood Hits	254	Shared Neighborhood Hits	96
SwissProt Accessions	Q8K4G2, Q5SUQ0	Gene names	Col23a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

CRK_HUMAN
θ value	θ > 10 (rank : 951)	NC score	0.137688 (rank : 220)
Query Neighborhood Hits	872	Target Neighborhood Hits	308	Shared Neighborhood Hits	127
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CRK_MOUSE
θ value	θ > 10 (rank : 952)	NC score	0.140578 (rank : 212)
Query Neighborhood Hits	872	Target Neighborhood Hits	314	Shared Neighborhood Hits	129
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CRSP2_HUMAN
θ value	θ > 10 (rank : 953)	NC score	0.119842 (rank : 263)
Query Neighborhood Hits	872	Target Neighborhood Hits	380	Shared Neighborhood Hits	184
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

CRSP7_HUMAN
θ value	θ > 10 (rank : 954)	NC score	0.068626 (rank : 557)
Query Neighborhood Hits	872	Target Neighborhood Hits	247	Shared Neighborhood Hits	119
SwissProt Accessions	O95402	Gene names	CRSP7, ARC70
Domain Architecture
Description	CRSP complex subunit 7 (Cofactor required for Sp1 transcriptional activation subunit 7) (Transcriptional coactivator CRSP70) (Activator- recruited cofactor 70 kDa component) (ARC70).

CS007_MOUSE
θ value	θ > 10 (rank : 955)	NC score	0.060483 (rank : 636)
Query Neighborhood Hits	872	Target Neighborhood Hits	464	Shared Neighborhood Hits	150
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

CSF1_HUMAN
θ value	θ > 10 (rank : 956)	NC score	0.112964 (rank : 290)
Query Neighborhood Hits	872	Target Neighborhood Hits	258	Shared Neighborhood Hits	112
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

CSKI1_MOUSE
θ value	θ > 10 (rank : 957)	NC score	0.095837 (rank : 356)
Query Neighborhood Hits	872	Target Neighborhood Hits	1031	Shared Neighborhood Hits	327
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CTDP1_HUMAN
θ value	θ > 10 (rank : 958)	NC score	0.085195 (rank : 431)
Query Neighborhood Hits	872	Target Neighborhood Hits	416	Shared Neighborhood Hits	165
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

DAB1_HUMAN
θ value	θ > 10 (rank : 959)	NC score	0.062042 (rank : 621)
Query Neighborhood Hits	872	Target Neighborhood Hits	219	Shared Neighborhood Hits	95
SwissProt Accessions	O75553, Q9NYA8	Gene names	DAB1
Domain Architecture
Description	Disabled homolog 1.

DAPP1_HUMAN
θ value	θ > 10 (rank : 960)	NC score	0.070644 (rank : 538)
Query Neighborhood Hits	872	Target Neighborhood Hits	227	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DAPP1_MOUSE
θ value	θ > 10 (rank : 961)	NC score	0.072480 (rank : 524)
Query Neighborhood Hits	872	Target Neighborhood Hits	225	Shared Neighborhood Hits	40
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DBNL_HUMAN
θ value	θ > 10 (rank : 962)	NC score	0.126606 (rank : 247)
Query Neighborhood Hits	872	Target Neighborhood Hits	244	Shared Neighborhood Hits	108
SwissProt Accessions	Q9UJU6, P84070, Q6IAI8, Q96F30, Q96K74, Q9HBN8, Q9NR72	Gene names	DBNL, CMAP, SH3P7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein).

DBNL_MOUSE
θ value	θ > 10 (rank : 963)	NC score	0.123694 (rank : 253)
Query Neighborhood Hits	872	Target Neighborhood Hits	306	Shared Neighborhood Hits	113
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

DCP1A_HUMAN
θ value	θ > 10 (rank : 964)	NC score	0.056110 (rank : 695)
Query Neighborhood Hits	872	Target Neighborhood Hits	228	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NPI6	Gene names	DCP1A, SMIF
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (Smad4-interacting transcriptional co-activator).

DDEF1_MOUSE
θ value	θ > 10 (rank : 965)	NC score	0.135456 (rank : 226)
Query Neighborhood Hits	872	Target Neighborhood Hits	592	Shared Neighborhood Hits	173
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

DDFL1_HUMAN
θ value	θ > 10 (rank : 966)	NC score	0.072067 (rank : 527)
Query Neighborhood Hits	872	Target Neighborhood Hits	353	Shared Neighborhood Hits	44
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

DDFL1_MOUSE
θ value	θ > 10 (rank : 967)	NC score	0.066769 (rank : 572)
Query Neighborhood Hits	872	Target Neighborhood Hits	324	Shared Neighborhood Hits	37
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

DOK2_MOUSE
θ value	θ > 10 (rank : 968)	NC score	0.078381 (rank : 483)
Query Neighborhood Hits	872	Target Neighborhood Hits	244	Shared Neighborhood Hits	140
SwissProt Accessions	O70469, O70272, Q99KL1	Gene names	Dok2, Frip
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)) (Dok- related protein) (Dok-R) (IL-four receptor-interacting protein) (FRIP).

ECT2_HUMAN
θ value	θ > 10 (rank : 969)	NC score	0.079916 (rank : 470)
Query Neighborhood Hits	872	Target Neighborhood Hits	98	Shared Neighborhood Hits	33
SwissProt Accessions	Q9H8V3, Q9NSV8, Q9NVW9	Gene names	ECT2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

ECT2_MOUSE
θ value	θ > 10 (rank : 970)	NC score	0.079659 (rank : 472)
Query Neighborhood Hits	872	Target Neighborhood Hits	98	Shared Neighborhood Hits	31
SwissProt Accessions	Q07139	Gene names	Ect2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

EDA_HUMAN
θ value	θ > 10 (rank : 971)	NC score	0.054029 (rank : 730)
Query Neighborhood Hits	872	Target Neighborhood Hits	134	Shared Neighborhood Hits	66
SwissProt Accessions	Q92838, O75910, Q5JUM7, Q9UP77, Q9Y6L0, Q9Y6L1, Q9Y6L2, Q9Y6L3, Q9Y6L4	Gene names	EDA, ED1
Domain Architecture
Description	Ectodysplasin-A (Ectodermal dysplasia protein) (EDA protein) [Contains: Ectodysplasin-A, membrane form; Ectodysplasin-A, secreted form].

EDA_MOUSE
θ value	θ > 10 (rank : 972)	NC score	0.055401 (rank : 702)
Query Neighborhood Hits	872	Target Neighborhood Hits	141	Shared Neighborhood Hits	66
SwissProt Accessions	O54693, O35705, Q9QWJ8, Q9QZ01, Q9QZ02	Gene names	Eda, Ed1, Ta
Domain Architecture
Description	Ectodysplasin-A (EDA protein homolog) (Tabby protein) [Contains: Ectodysplasin-A, membrane form; Ectodysplasin-A, secreted form].

ELN_HUMAN
θ value	θ > 10 (rank : 973)	NC score	0.054773 (rank : 714)
Query Neighborhood Hits	872	Target Neighborhood Hits	85	Shared Neighborhood Hits	36
SwissProt Accessions	P15502, O15336, O15337, Q14233, Q14234, Q14235, Q14238, Q6P0L4, Q6ZWJ6, Q75MU5, Q7Z316, Q7Z3F5, Q9UMF5	Gene names	ELN
Domain Architecture	No domain graphic available
Description	Elastin precursor (Tropoelastin).

EMID1_MOUSE
θ value	θ > 10 (rank : 974)	NC score	0.063076 (rank : 605)
Query Neighborhood Hits	872	Target Neighborhood Hits	230	Shared Neighborhood Hits	89
SwissProt Accessions	Q91VF5	Gene names	Emid1, Emu1
Domain Architecture	No domain graphic available
Description	EMI domain-containing protein 1 precursor (Protein Emu1) (Emilin and multimerin domain-containing protein 1).

EMID2_HUMAN
θ value	θ > 10 (rank : 975)	NC score	0.071043 (rank : 537)
Query Neighborhood Hits	872	Target Neighborhood Hits	226	Shared Neighborhood Hits	95
SwissProt Accessions	Q96A83	Gene names	EMID2, COL26A1, EMU2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXVI) chain precursor (EMI domain-containing protein 2) (Protein Emu2) (Emilin and multimerin domain-containing protein 2).

ENAM_MOUSE
θ value	θ > 10 (rank : 976)	NC score	0.053622 (rank : 737)
Query Neighborhood Hits	872	Target Neighborhood Hits	229	Shared Neighborhood Hits	89
SwissProt Accessions	O55196	Gene names	Enam
Domain Architecture	No domain graphic available
Description	Enamelin precursor.

EPN3_HUMAN
θ value	θ > 10 (rank : 977)	NC score	0.069044 (rank : 552)
Query Neighborhood Hits	872	Target Neighborhood Hits	197	Shared Neighborhood Hits	86
SwissProt Accessions	Q9H201, Q9BVN6, Q9NWK2	Gene names	EPN3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

EPS8_HUMAN
θ value	θ > 10 (rank : 978)	NC score	0.051584 (rank : 760)
Query Neighborhood Hits	872	Target Neighborhood Hits	151	Shared Neighborhood Hits	84
SwissProt Accessions	Q12929, Q8N6J0	Gene names	EPS8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

EPS8_MOUSE
θ value	θ > 10 (rank : 979)	NC score	0.051164 (rank : 767)
Query Neighborhood Hits	872	Target Neighborhood Hits	157	Shared Neighborhood Hits	86
SwissProt Accessions	Q08509	Gene names	Eps8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

ES8L3_HUMAN
θ value	θ > 10 (rank : 980)	NC score	0.053963 (rank : 732)
Query Neighborhood Hits	872	Target Neighborhood Hits	206	Shared Neighborhood Hits	90
SwissProt Accessions	Q8TE67, Q5T8Q6, Q5T8Q7, Q5T8Q8, Q96E47, Q9H719	Gene names	EPS8L3, EPS8R3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

ES8L3_MOUSE
θ value	θ > 10 (rank : 981)	NC score	0.062938 (rank : 606)
Query Neighborhood Hits	872	Target Neighborhood Hits	168	Shared Neighborhood Hits	88
SwissProt Accessions	Q91WL0, Q3TJ14	Gene names	Eps8l3, Eps8r3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor pathway substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

FA13A_HUMAN
θ value	θ > 10 (rank : 982)	NC score	0.054601 (rank : 719)
Query Neighborhood Hits	872	Target Neighborhood Hits	102	Shared Neighborhood Hits	5
SwissProt Accessions	O94988, Q8NBA3	Gene names	FAM13A1, KIAA0914
Domain Architecture	No domain graphic available
Description	Protein FAM13A1.

FA13A_MOUSE
θ value	θ > 10 (rank : 983)	NC score	0.055775 (rank : 698)
Query Neighborhood Hits	872	Target Neighborhood Hits	83	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BGI4, Q8BZ91	Gene names	Fam13a1, Precm1
Domain Architecture	No domain graphic available
Description	Protein FAM13A1 (Precm1 protein).

FA47A_HUMAN
θ value	θ > 10 (rank : 984)	NC score	0.110054 (rank : 302)
Query Neighborhood Hits	872	Target Neighborhood Hits	451	Shared Neighborhood Hits	169
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

FA47B_HUMAN
θ value	θ > 10 (rank : 985)	NC score	0.128575 (rank : 243)
Query Neighborhood Hits	872	Target Neighborhood Hits	431	Shared Neighborhood Hits	181
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

FARP2_HUMAN
θ value	θ > 10 (rank : 986)	NC score	0.051953 (rank : 752)
Query Neighborhood Hits	872	Target Neighborhood Hits	240	Shared Neighborhood Hits	57
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FARP2_MOUSE
θ value	θ > 10 (rank : 987)	NC score	0.052823 (rank : 745)
Query Neighborhood Hits	872	Target Neighborhood Hits	209	Shared Neighborhood Hits	49
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FGD2_HUMAN
θ value	θ > 10 (rank : 988)	NC score	0.063553 (rank : 602)
Query Neighborhood Hits	872	Target Neighborhood Hits	151	Shared Neighborhood Hits	31
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

FGD2_MOUSE
θ value	θ > 10 (rank : 989)	NC score	0.060017 (rank : 643)
Query Neighborhood Hits	872	Target Neighborhood Hits	163	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

FGD3_HUMAN
θ value	θ > 10 (rank : 990)	NC score	0.069483 (rank : 546)
Query Neighborhood Hits	872	Target Neighborhood Hits	249	Shared Neighborhood Hits	61
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

FGD3_MOUSE
θ value	θ > 10 (rank : 991)	NC score	0.069380 (rank : 547)
Query Neighborhood Hits	872	Target Neighborhood Hits	257	Shared Neighborhood Hits	51
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

FGD4_HUMAN
θ value	θ > 10 (rank : 992)	NC score	0.066399 (rank : 575)
Query Neighborhood Hits	872	Target Neighborhood Hits	219	Shared Neighborhood Hits	40
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

FGD4_MOUSE
θ value	θ > 10 (rank : 993)	NC score	0.067638 (rank : 566)
Query Neighborhood Hits	872	Target Neighborhood Hits	227	Shared Neighborhood Hits	41
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

FGD6_HUMAN
θ value	θ > 10 (rank : 994)	NC score	0.054871 (rank : 712)
Query Neighborhood Hits	872	Target Neighborhood Hits	237	Shared Neighborhood Hits	38
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

FGD6_MOUSE
θ value	θ > 10 (rank : 995)	NC score	0.060838 (rank : 631)
Query Neighborhood Hits	872	Target Neighborhood Hits	282	Shared Neighborhood Hits	57
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

GA2L2_MOUSE
θ value	θ > 10 (rank : 996)	NC score	0.083341 (rank : 449)
Query Neighborhood Hits	872	Target Neighborhood Hits	395	Shared Neighborhood Hits	169
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

GAB1_HUMAN
θ value	θ > 10 (rank : 997)	NC score	0.060792 (rank : 632)
Query Neighborhood Hits	872	Target Neighborhood Hits	279	Shared Neighborhood Hits	120
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

GAK11_HUMAN
θ value	θ > 10 (rank : 998)	NC score	0.055256 (rank : 704)
Query Neighborhood Hits	872	Target Neighborhood Hits	409	Shared Neighborhood Hits	200
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK2_HUMAN
θ value	θ > 10 (rank : 999)	NC score	0.054855 (rank : 713)
Query Neighborhood Hits	872	Target Neighborhood Hits	406	Shared Neighborhood Hits	197
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK4_HUMAN
θ value	θ > 10 (rank : 1000)	NC score	0.055555 (rank : 701)
Query Neighborhood Hits	872	Target Neighborhood Hits	415	Shared Neighborhood Hits	202
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK5_HUMAN
θ value	θ > 10 (rank : 1001)	NC score	0.056517 (rank : 687)
Query Neighborhood Hits	872	Target Neighborhood Hits	429	Shared Neighborhood Hits	211
SwissProt Accessions	P62684	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K113 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK6_HUMAN
θ value	θ > 10 (rank : 1002)	NC score	0.052597 (rank : 748)
Query Neighborhood Hits	872	Target Neighborhood Hits	392	Shared Neighborhood Hits	195
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GIT1_HUMAN
θ value	θ > 10 (rank : 1003)	NC score	0.050921 (rank : 773)
Query Neighborhood Hits	872	Target Neighborhood Hits	336	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

GIT1_MOUSE
θ value	θ > 10 (rank : 1004)	NC score	0.050198 (rank : 777)
Query Neighborhood Hits	872	Target Neighborhood Hits	341	Shared Neighborhood Hits	28
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

GIT2_MOUSE
θ value	θ > 10 (rank : 1005)	NC score	0.051768 (rank : 756)
Query Neighborhood Hits	872	Target Neighborhood Hits	323	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

GNRP_HUMAN
θ value	θ > 10 (rank : 1006)	NC score	0.074895 (rank : 508)
Query Neighborhood Hits	872	Target Neighborhood Hits	239	Shared Neighborhood Hits	44
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

GNRP_MOUSE
θ value	θ > 10 (rank : 1007)	NC score	0.079724 (rank : 471)
Query Neighborhood Hits	872	Target Neighborhood Hits	191	Shared Neighborhood Hits	44
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

GPS2_HUMAN
θ value	θ > 10 (rank : 1008)	NC score	0.095583 (rank : 358)
Query Neighborhood Hits	872	Target Neighborhood Hits	459	Shared Neighborhood Hits	127
SwissProt Accessions	Q13227	Gene names	GPS2
Domain Architecture	No domain graphic available
Description	G protein pathway suppressor 2 (Protein GPS2).

GRIN1_MOUSE
θ value	θ > 10 (rank : 1009)	NC score	0.060161 (rank : 639)
Query Neighborhood Hits	872	Target Neighborhood Hits	337	Shared Neighborhood Hits	91
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

GRP3_HUMAN
θ value	θ > 10 (rank : 1010)	NC score	0.088756 (rank : 404)
Query Neighborhood Hits	872	Target Neighborhood Hits	131	Shared Neighborhood Hits	25
SwissProt Accessions	Q8IV61, O94931	Gene names	RASGRP3, GRP3, KIAA0846
Domain Architecture
Description	RAS guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1).

HGS_HUMAN
θ value	θ > 10 (rank : 1011)	NC score	0.055173 (rank : 706)
Query Neighborhood Hits	872	Target Neighborhood Hits	517	Shared Neighborhood Hits	109
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

HGS_MOUSE
θ value	θ > 10 (rank : 1012)	NC score	0.060066 (rank : 641)
Query Neighborhood Hits	872	Target Neighborhood Hits	589	Shared Neighborhood Hits	139
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

HRBL_HUMAN
θ value	θ > 10 (rank : 1013)	NC score	0.067362 (rank : 567)
Query Neighborhood Hits	872	Target Neighborhood Hits	179	Shared Neighborhood Hits	85
SwissProt Accessions	O95081, O75429, Q96AB9, Q96GL4	Gene names	HRBL, RABR
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

HRBL_MOUSE
θ value	θ > 10 (rank : 1014)	NC score	0.090031 (rank : 396)
Query Neighborhood Hits	872	Target Neighborhood Hits	269	Shared Neighborhood Hits	129
SwissProt Accessions	Q80WC7, Q8BKS5, Q99J67	Gene names	Hrbl, Rabr
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

IF4B_HUMAN
θ value	θ > 10 (rank : 1015)	NC score	0.056197 (rank : 693)
Query Neighborhood Hits	872	Target Neighborhood Hits	417	Shared Neighborhood Hits	104
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

IF4G1_MOUSE
θ value	θ > 10 (rank : 1016)	NC score	0.078703 (rank : 480)
Query Neighborhood Hits	872	Target Neighborhood Hits	534	Shared Neighborhood Hits	216
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

INP5E_HUMAN
θ value	θ > 10 (rank : 1017)	NC score	0.063403 (rank : 603)
Query Neighborhood Hits	872	Target Neighborhood Hits	201	Shared Neighborhood Hits	102
SwissProt Accessions	Q9NRR6, Q15734	Gene names	INPP5E
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

IWS1_HUMAN
θ value	θ > 10 (rank : 1018)	NC score	0.051110 (rank : 768)
Query Neighborhood Hits	872	Target Neighborhood Hits	1241	Shared Neighborhood Hits	159
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

JIP1_HUMAN
θ value	θ > 10 (rank : 1019)	NC score	0.062266 (rank : 618)
Query Neighborhood Hits	872	Target Neighborhood Hits	271	Shared Neighborhood Hits	121
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

JIP1_MOUSE
θ value	θ > 10 (rank : 1020)	NC score	0.061181 (rank : 625)
Query Neighborhood Hits	872	Target Neighborhood Hits	259	Shared Neighborhood Hits	116
SwissProt Accessions	Q9WVI9, O35145, Q925J8, Q9R1H9, Q9R1Z1, Q9WVI7, Q9WVI8	Gene names	Mapk8ip1, Ib1, Jip1, Mapk8ip, Prkm8ip
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain-1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

JIP2_HUMAN
θ value	θ > 10 (rank : 1021)	NC score	0.058592 (rank : 663)
Query Neighborhood Hits	872	Target Neighborhood Hits	288	Shared Neighborhood Hits	137
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

JPH2_HUMAN
θ value	θ > 10 (rank : 1022)	NC score	0.090031 (rank : 397)
Query Neighborhood Hits	872	Target Neighborhood Hits	639	Shared Neighborhood Hits	261
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

K1543_HUMAN
θ value	θ > 10 (rank : 1023)	NC score	0.101815 (rank : 330)
Query Neighborhood Hits	872	Target Neighborhood Hits	435	Shared Neighborhood Hits	172
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

K1683_HUMAN
θ value	θ > 10 (rank : 1024)	NC score	0.083803 (rank : 445)
Query Neighborhood Hits	872	Target Neighborhood Hits	240	Shared Neighborhood Hits	90
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

LASP1_HUMAN
θ value	θ > 10 (rank : 1025)	NC score	0.112271 (rank : 295)
Query Neighborhood Hits	872	Target Neighborhood Hits	293	Shared Neighborhood Hits	120
SwissProt Accessions	Q14847, Q96ED2, Q96IG0	Gene names	LASP1, MLN50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

LASP1_MOUSE
θ value	θ > 10 (rank : 1026)	NC score	0.110986 (rank : 299)
Query Neighborhood Hits	872	Target Neighborhood Hits	297	Shared Neighborhood Hits	119
SwissProt Accessions	Q61792, Q62416	Gene names	Lasp1, Mln50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

LCP2_HUMAN
θ value	θ > 10 (rank : 1027)	NC score	0.154656 (rank : 185)
Query Neighborhood Hits	872	Target Neighborhood Hits	531	Shared Neighborhood Hits	216
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

LR37A_HUMAN
θ value	θ > 10 (rank : 1028)	NC score	0.054266 (rank : 723)
Query Neighborhood Hits	872	Target Neighborhood Hits	720	Shared Neighborhood Hits	141
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

MAGE1_HUMAN
θ value	θ > 10 (rank : 1029)	NC score	0.199240 (rank : 106)
Query Neighborhood Hits	872	Target Neighborhood Hits	1389	Shared Neighborhood Hits	437
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MAML1_MOUSE
θ value	θ > 10 (rank : 1030)	NC score	0.058118 (rank : 671)
Query Neighborhood Hits	872	Target Neighborhood Hits	279	Shared Neighborhood Hits	113
SwissProt Accessions	Q6T264, Q505D8, Q5SUC2, Q6PDK3, Q6ZQG5, Q8BIU5, Q8R3T0	Gene names	Maml1, Kiaa0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

MAML3_HUMAN
θ value	θ > 10 (rank : 1031)	NC score	0.067651 (rank : 565)
Query Neighborhood Hits	872	Target Neighborhood Hits	323	Shared Neighborhood Hits	112
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

MAP1A_HUMAN
θ value	θ > 10 (rank : 1032)	NC score	0.080229 (rank : 467)
Query Neighborhood Hits	872	Target Neighborhood Hits	1626	Shared Neighborhood Hits	299
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MAP4_HUMAN
θ value	θ > 10 (rank : 1033)	NC score	0.051907 (rank : 754)
Query Neighborhood Hits	872	Target Neighborhood Hits	428	Shared Neighborhood Hits	108
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MARCO_MOUSE
θ value	θ > 10 (rank : 1034)	NC score	0.052752 (rank : 746)
Query Neighborhood Hits	872	Target Neighborhood Hits	242	Shared Neighborhood Hits	63
SwissProt Accessions	Q60754	Gene names	Marco
Domain Architecture
Description	Macrophage receptor MARCO (Macrophage receptor with collagenous structure).

MARCS_HUMAN
θ value	θ > 10 (rank : 1035)	NC score	0.050894 (rank : 774)
Query Neighborhood Hits	872	Target Neighborhood Hits	204	Shared Neighborhood Hits	57
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

MARCS_MOUSE
θ value	θ > 10 (rank : 1036)	NC score	0.053271 (rank : 741)
Query Neighborhood Hits	872	Target Neighborhood Hits	227	Shared Neighborhood Hits	55
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

MBB1A_HUMAN
θ value	θ > 10 (rank : 1037)	NC score	0.084459 (rank : 438)
Query Neighborhood Hits	872	Target Neighborhood Hits	665	Shared Neighborhood Hits	184
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

MCF2L_MOUSE
θ value	θ > 10 (rank : 1038)	NC score	0.066629 (rank : 574)
Query Neighborhood Hits	872	Target Neighborhood Hits	255	Shared Neighborhood Hits	49
SwissProt Accessions	Q64096	Gene names	Mcf2l, Dbs
Domain Architecture
Description	Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2- transforming sequence-like protein).

MCF2_HUMAN
θ value	θ > 10 (rank : 1039)	NC score	0.070250 (rank : 541)
Query Neighborhood Hits	872	Target Neighborhood Hits	166	Shared Neighborhood Hits	37
SwissProt Accessions	P10911, P14919, Q5JYJ4, Q8IUF3, Q8IUF4, Q9UJB3	Gene names	MCF2, DBL
Domain Architecture
Description	Proto-oncogene DBL (Proto-oncogene MCF-2) [Contains: MCF2-transforming protein; DBL-transforming protein].

MDC1_HUMAN
θ value	θ > 10 (rank : 1040)	NC score	0.150144 (rank : 194)
Query Neighborhood Hits	872	Target Neighborhood Hits	1446	Shared Neighborhood Hits	291
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MDC1_MOUSE
θ value	θ > 10 (rank : 1041)	NC score	0.153365 (rank : 187)
Query Neighborhood Hits	872	Target Neighborhood Hits	998	Shared Neighborhood Hits	269
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MLL3_MOUSE
θ value	θ > 10 (rank : 1042)	NC score	0.151446 (rank : 192)
Query Neighborhood Hits	872	Target Neighborhood Hits	1399	Shared Neighborhood Hits	350
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MTSS1_HUMAN
θ value	θ > 10 (rank : 1043)	NC score	0.086323 (rank : 423)
Query Neighborhood Hits	872	Target Neighborhood Hits	504	Shared Neighborhood Hits	179
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

MTSS1_MOUSE
θ value	θ > 10 (rank : 1044)	NC score	0.117260 (rank : 275)
Query Neighborhood Hits	872	Target Neighborhood Hits	592	Shared Neighborhood Hits	243
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

MUC1_MOUSE
θ value	θ > 10 (rank : 1045)	NC score	0.056665 (rank : 683)
Query Neighborhood Hits	872	Target Neighborhood Hits	388	Shared Neighborhood Hits	73
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

MUCDL_HUMAN
θ value	θ > 10 (rank : 1046)	NC score	0.116107 (rank : 280)
Query Neighborhood Hits	872	Target Neighborhood Hits	777	Shared Neighborhood Hits	280
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

MYO10_HUMAN
θ value	θ > 10 (rank : 1047)	NC score	0.055320 (rank : 703)
Query Neighborhood Hits	872	Target Neighborhood Hits	920	Shared Neighborhood Hits	75
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

NCF4_HUMAN
θ value	θ > 10 (rank : 1048)	NC score	0.164057 (rank : 164)
Query Neighborhood Hits	872	Target Neighborhood Hits	161	Shared Neighborhood Hits	101
SwissProt Accessions	Q15080, O60808, Q86U56, Q9BU98, Q9NP45	Gene names	NCF4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

NCOR2_HUMAN
θ value	θ > 10 (rank : 1049)	NC score	0.054238 (rank : 724)
Query Neighborhood Hits	872	Target Neighborhood Hits	870	Shared Neighborhood Hits	191
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

NEBL_HUMAN
θ value	θ > 10 (rank : 1050)	NC score	0.101582 (rank : 331)
Query Neighborhood Hits	872	Target Neighborhood Hits	457	Shared Neighborhood Hits	121
SwissProt Accessions	O76041, Q9UIC4	Gene names	NEBL
Domain Architecture
Description	Nebulette (Actin-binding Z-disk protein).

NEBU_HUMAN
θ value	θ > 10 (rank : 1051)	NC score	0.092075 (rank : 381)
Query Neighborhood Hits	872	Target Neighborhood Hits	420	Shared Neighborhood Hits	121
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

NFRKB_MOUSE
θ value	θ > 10 (rank : 1052)	NC score	0.057071 (rank : 679)
Query Neighborhood Hits	872	Target Neighborhood Hits	393	Shared Neighborhood Hits	122
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

NOLC1_HUMAN
θ value	θ > 10 (rank : 1053)	NC score	0.053984 (rank : 731)
Query Neighborhood Hits	872	Target Neighborhood Hits	452	Shared Neighborhood Hits	72
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

NOXO1_MOUSE
θ value	θ > 10 (rank : 1054)	NC score	0.117604 (rank : 273)
Query Neighborhood Hits	872	Target Neighborhood Hits	114	Shared Neighborhood Hits	82
SwissProt Accessions	Q8VCM2, Q3TZA4, Q8BH41, Q9D747	Gene names	Noxo1, Snx28
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Sorting nexin-28).

NPHP1_HUMAN
θ value	θ > 10 (rank : 1055)	NC score	0.109201 (rank : 305)
Query Neighborhood Hits	872	Target Neighborhood Hits	288	Shared Neighborhood Hits	105
SwissProt Accessions	O15259, O14837	Gene names	NPHP1, NPH1
Domain Architecture
Description	Nephrocystin-1 (Juvenile nephronophthisis 1 protein).

NPHP1_MOUSE
θ value	θ > 10 (rank : 1056)	NC score	0.123094 (rank : 255)
Query Neighborhood Hits	872	Target Neighborhood Hits	267	Shared Neighborhood Hits	114
SwissProt Accessions	Q9QY53, Q9D7G8, Q9QZP0, Q9WUZ2	Gene names	Nphp1, Nph1
Domain Architecture
Description	Nephrocystin-1.

NU214_HUMAN
θ value	θ > 10 (rank : 1057)	NC score	0.063971 (rank : 598)
Query Neighborhood Hits	872	Target Neighborhood Hits	657	Shared Neighborhood Hits	138
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

NUMBL_HUMAN
θ value	θ > 10 (rank : 1058)	NC score	0.117290 (rank : 274)
Query Neighborhood Hits	872	Target Neighborhood Hits	394	Shared Neighborhood Hits	213
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

NUP53_HUMAN
θ value	θ > 10 (rank : 1059)	NC score	0.075265 (rank : 507)
Query Neighborhood Hits	872	Target Neighborhood Hits	156	Shared Neighborhood Hits	101
SwissProt Accessions	Q8NFH5, Q4ZFZ9, Q53S95, Q8TDJ1	Gene names	NUP35, MP44, NUP53
Domain Architecture	No domain graphic available
Description	Nucleoporin NUP53 (Nuclear pore complex protein Nup53) (Nucleoporin Nup35) (35 kDa nucleoporin) (Mitotic phosphoprotein 44) (MP-44).

OBF1_HUMAN
θ value	θ > 10 (rank : 1060)	NC score	0.078059 (rank : 485)
Query Neighborhood Hits	872	Target Neighborhood Hits	203	Shared Neighborhood Hits	114
SwissProt Accessions	Q16633, Q14983	Gene names	POU2AF1, OBF1
Domain Architecture	No domain graphic available
Description	POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (OCT-binding factor 1) (BOB-1) (OCA-B).

P55G_HUMAN
θ value	θ > 10 (rank : 1061)	NC score	0.074085 (rank : 513)
Query Neighborhood Hits	872	Target Neighborhood Hits	451	Shared Neighborhood Hits	40
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

P55G_MOUSE
θ value	θ > 10 (rank : 1062)	NC score	0.072174 (rank : 526)
Query Neighborhood Hits	872	Target Neighborhood Hits	401	Shared Neighborhood Hits	36
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

PACN3_HUMAN
θ value	θ > 10 (rank : 1063)	NC score	0.128112 (rank : 244)
Query Neighborhood Hits	872	Target Neighborhood Hits	385	Shared Neighborhood Hits	122
SwissProt Accessions	Q9UKS6, Q9H331, Q9NWV9	Gene names	PACSIN3
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) (Endophilin I).

PCQAP_MOUSE
θ value	θ > 10 (rank : 1064)	NC score	0.062627 (rank : 611)
Query Neighborhood Hits	872	Target Neighborhood Hits	506	Shared Neighborhood Hits	103
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

PDLI7_HUMAN
θ value	θ > 10 (rank : 1065)	NC score	0.050924 (rank : 772)
Query Neighborhood Hits	872	Target Neighborhood Hits	547	Shared Neighborhood Hits	170
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

PDZD8_HUMAN
θ value	θ > 10 (rank : 1066)	NC score	0.060271 (rank : 638)
Query Neighborhood Hits	872	Target Neighborhood Hits	185	Shared Neighborhood Hits	31
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

PER2_MOUSE
θ value	θ > 10 (rank : 1067)	NC score	0.069356 (rank : 548)
Query Neighborhood Hits	872	Target Neighborhood Hits	325	Shared Neighborhood Hits	136
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

PEX13_HUMAN
θ value	θ > 10 (rank : 1068)	NC score	0.093072 (rank : 373)
Query Neighborhood Hits	872	Target Neighborhood Hits	128	Shared Neighborhood Hits	85
SwissProt Accessions	Q92968	Gene names	PEX13
Domain Architecture
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

PEX13_MOUSE
θ value	θ > 10 (rank : 1069)	NC score	0.092993 (rank : 374)
Query Neighborhood Hits	872	Target Neighborhood Hits	126	Shared Neighborhood Hits	84
SwissProt Accessions	Q9D0K1, Q3U5T1, Q8CCJ5, Q8CCW5, Q99MM2, Q9EPK1	Gene names	Pex13
Domain Architecture	No domain graphic available
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

PKHA6_HUMAN
θ value	θ > 10 (rank : 1070)	NC score	0.074694 (rank : 511)
Query Neighborhood Hits	872	Target Neighborhood Hits	556	Shared Neighborhood Hits	146
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA6_MOUSE
θ value	θ > 10 (rank : 1071)	NC score	0.070505 (rank : 539)
Query Neighborhood Hits	872	Target Neighborhood Hits	591	Shared Neighborhood Hits	135
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHG1_HUMAN
θ value	θ > 10 (rank : 1072)	NC score	0.087579 (rank : 411)
Query Neighborhood Hits	872	Target Neighborhood Hits	174	Shared Neighborhood Hits	40
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

PKHG4_HUMAN
θ value	θ > 10 (rank : 1073)	NC score	0.061662 (rank : 622)
Query Neighborhood Hits	872	Target Neighborhood Hits	200	Shared Neighborhood Hits	84
SwissProt Accessions	Q58EX7, Q4G0J8, Q4H485, Q56A69, Q9H7K4, Q9UFW0	Gene names	PLEKHG4, PRTPHN1
Domain Architecture	No domain graphic available
Description	Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1).

PLCG1_HUMAN
θ value	θ > 10 (rank : 1074)	NC score	0.106926 (rank : 312)
Query Neighborhood Hits	872	Target Neighborhood Hits	293	Shared Neighborhood Hits	116
SwissProt Accessions	P19174, Q2V575	Gene names	PLCG1, PLC1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

PLCG1_MOUSE
θ value	θ > 10 (rank : 1075)	NC score	0.111123 (rank : 297)
Query Neighborhood Hits	872	Target Neighborhood Hits	314	Shared Neighborhood Hits	122
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

PLCG2_HUMAN
θ value	θ > 10 (rank : 1076)	NC score	0.106694 (rank : 315)
Query Neighborhood Hits	872	Target Neighborhood Hits	280	Shared Neighborhood Hits	113
SwissProt Accessions	P16885, Q969T5	Gene names	PLCG2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV).

PREX1_HUMAN
θ value	θ > 10 (rank : 1077)	NC score	0.095184 (rank : 359)
Query Neighborhood Hits	872	Target Neighborhood Hits	177	Shared Neighborhood Hits	39
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

PRG4_MOUSE
θ value	θ > 10 (rank : 1078)	NC score	0.056346 (rank : 691)
Query Neighborhood Hits	872	Target Neighborhood Hits	624	Shared Neighborhood Hits	120
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRP5_HUMAN
θ value	θ > 10 (rank : 1079)	NC score	0.081912 (rank : 457)
Query Neighborhood Hits	872	Target Neighborhood Hits	108	Shared Neighborhood Hits	54
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

PRPC_HUMAN
θ value	θ > 10 (rank : 1080)	NC score	0.063824 (rank : 600)
Query Neighborhood Hits	872	Target Neighborhood Hits	165	Shared Neighborhood Hits	54
SwissProt Accessions	P02810, Q4VBP2, Q53XA2, Q6P2F6	Gene names	PRH1
Domain Architecture	No domain graphic available
Description	Salivary acidic proline-rich phosphoprotein 1/2 precursor (PRP-1/PRP- 2) (Parotid proline-rich protein 1/2) (Pr1/Pr2) (Protein C) (Parotid acidic protein) (Pa) (Parotid isoelectric focusing variant protein) (PIF-S) (Parotid double-band protein) (Db-s) [Contains: Salivary acidic proline-rich phosphoprotein 1/2; Salivary acidic proline-rich phosphoprotein 3/4 (PRP-3/PRP-4) (Protein A) (PIF-F) (Db-F); Peptide P-C].

R3HD2_MOUSE
θ value	θ > 10 (rank : 1081)	NC score	0.098484 (rank : 338)
Query Neighborhood Hits	872	Target Neighborhood Hits	397	Shared Neighborhood Hits	149
SwissProt Accessions	Q80TM6, Q80YB1, Q8BLS5, Q9CW50	Gene names	R3hdm2, Kiaa1002
Domain Architecture
Description	R3H domain-containing protein 2.

RASA1_HUMAN
θ value	θ > 10 (rank : 1082)	NC score	0.052273 (rank : 751)
Query Neighborhood Hits	872	Target Neighborhood Hits	258	Shared Neighborhood Hits	48
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

RGNEF_MOUSE
θ value	θ > 10 (rank : 1083)	NC score	0.065527 (rank : 584)
Query Neighborhood Hits	872	Target Neighborhood Hits	641	Shared Neighborhood Hits	69
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

RIMB1_HUMAN
θ value	θ > 10 (rank : 1084)	NC score	0.080536 (rank : 464)
Query Neighborhood Hits	872	Target Neighborhood Hits	1479	Shared Neighborhood Hits	274
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RIMB2_HUMAN
θ value	θ > 10 (rank : 1085)	NC score	0.086115 (rank : 425)
Query Neighborhood Hits	872	Target Neighborhood Hits	263	Shared Neighborhood Hits	107
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

RIMB2_MOUSE
θ value	θ > 10 (rank : 1086)	NC score	0.084358 (rank : 441)
Query Neighborhood Hits	872	Target Neighborhood Hits	246	Shared Neighborhood Hits	95
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

RPTN_MOUSE
θ value	θ > 10 (rank : 1087)	NC score	0.056603 (rank : 686)
Query Neighborhood Hits	872	Target Neighborhood Hits	650	Shared Neighborhood Hits	106
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

RTP3_MOUSE
θ value	θ > 10 (rank : 1088)	NC score	0.086301 (rank : 424)
Query Neighborhood Hits	872	Target Neighborhood Hits	374	Shared Neighborhood Hits	128
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

SASH1_MOUSE
θ value	θ > 10 (rank : 1089)	NC score	0.058487 (rank : 665)
Query Neighborhood Hits	872	Target Neighborhood Hits	263	Shared Neighborhood Hits	102
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

SELPL_MOUSE
θ value	θ > 10 (rank : 1090)	NC score	0.113075 (rank : 289)
Query Neighborhood Hits	872	Target Neighborhood Hits	588	Shared Neighborhood Hits	182
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SELV_HUMAN
θ value	θ > 10 (rank : 1091)	NC score	0.051400 (rank : 763)
Query Neighborhood Hits	872	Target Neighborhood Hits	118	Shared Neighborhood Hits	54
SwissProt Accessions	P59797	Gene names	SELV
Domain Architecture	No domain graphic available
Description	Selenoprotein V.

SF3B1_HUMAN
θ value	θ > 10 (rank : 1092)	NC score	0.059528 (rank : 648)
Query Neighborhood Hits	872	Target Neighborhood Hits	341	Shared Neighborhood Hits	117
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_MOUSE
θ value	θ > 10 (rank : 1093)	NC score	0.059279 (rank : 653)
Query Neighborhood Hits	872	Target Neighborhood Hits	352	Shared Neighborhood Hits	118
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SHLB1_HUMAN
θ value	θ > 10 (rank : 1094)	NC score	0.053575 (rank : 738)
Query Neighborhood Hits	872	Target Neighborhood Hits	96	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Y371, Q9H3Z0, Q9NR47, Q9NYA9	Gene names	SH3GLB1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1) (Bax- interacting factor 1) (Bif-1).

SHLB1_MOUSE
θ value	θ > 10 (rank : 1095)	NC score	0.055009 (rank : 707)
Query Neighborhood Hits	872	Target Neighborhood Hits	101	Shared Neighborhood Hits	66
SwissProt Accessions	Q9JK48, Q8CDS9, Q8VI52, Q9CT31	Gene names	Sh3glb1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1).

SHLB2_HUMAN
θ value	θ > 10 (rank : 1096)	NC score	0.058895 (rank : 657)
Query Neighborhood Hits	872	Target Neighborhood Hits	86	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NR46, Q8WY61, Q96JH9	Gene names	SH3GLB2, KIAA1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

SHLB2_MOUSE
θ value	θ > 10 (rank : 1097)	NC score	0.058830 (rank : 661)
Query Neighborhood Hits	872	Target Neighborhood Hits	88	Shared Neighborhood Hits	52
SwissProt Accessions	Q8R3V5, Q8K140, Q91ZI7	Gene names	Sh3glb2, Kiaa1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

SMAP1_HUMAN
θ value	θ > 10 (rank : 1098)	NC score	0.058477 (rank : 666)
Query Neighborhood Hits	872	Target Neighborhood Hits	98	Shared Neighborhood Hits	28
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SMAP1_MOUSE
θ value	θ > 10 (rank : 1099)	NC score	0.059903 (rank : 645)
Query Neighborhood Hits	872	Target Neighborhood Hits	120	Shared Neighborhood Hits	36
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SMOO_HUMAN
θ value	θ > 10 (rank : 1100)	NC score	0.056654 (rank : 684)
Query Neighborhood Hits	872	Target Neighborhood Hits	391	Shared Neighborhood Hits	120
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

SMP1L_HUMAN
θ value	θ > 10 (rank : 1101)	NC score	0.058843 (rank : 659)
Query Neighborhood Hits	872	Target Neighborhood Hits	74	Shared Neighborhood Hits	23
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

SMP1L_MOUSE
θ value	θ > 10 (rank : 1102)	NC score	0.058023 (rank : 672)
Query Neighborhood Hits	872	Target Neighborhood Hits	70	Shared Neighborhood Hits	20
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

SNPC4_HUMAN
θ value	θ > 10 (rank : 1103)	NC score	0.131017 (rank : 238)
Query Neighborhood Hits	872	Target Neighborhood Hits	589	Shared Neighborhood Hits	246
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

SNX18_MOUSE
θ value	θ > 10 (rank : 1104)	NC score	0.082852 (rank : 453)
Query Neighborhood Hits	872	Target Neighborhood Hits	198	Shared Neighborhood Hits	96
SwissProt Accessions	Q91ZR2	Gene names	Snag1, Snx18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

SNX9_HUMAN
θ value	θ > 10 (rank : 1105)	NC score	0.051079 (rank : 769)
Query Neighborhood Hits	872	Target Neighborhood Hits	148	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y5X1, Q9BSI7, Q9BVM1, Q9UJH6, Q9UP20	Gene names	SNX9, SH3PX1
Domain Architecture
Description	Sorting nexin-9 (SH3 and PX domain-containing protein 1) (SDP1 protein).

SON_HUMAN
θ value	θ > 10 (rank : 1106)	NC score	0.234721 (rank : 79)
Query Neighborhood Hits	872	Target Neighborhood Hits	1568	Shared Neighborhood Hits	484
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

SON_MOUSE
θ value	θ > 10 (rank : 1107)	NC score	0.121113 (rank : 259)
Query Neighborhood Hits	872	Target Neighborhood Hits	957	Shared Neighborhood Hits	284
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

SOX13_HUMAN
θ value	θ > 10 (rank : 1108)	NC score	0.076013 (rank : 504)
Query Neighborhood Hits	872	Target Neighborhood Hits	464	Shared Neighborhood Hits	169
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

SOX13_MOUSE
θ value	θ > 10 (rank : 1109)	NC score	0.062144 (rank : 620)
Query Neighborhood Hits	872	Target Neighborhood Hits	495	Shared Neighborhood Hits	167
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

SOX30_MOUSE
θ value	θ > 10 (rank : 1110)	NC score	0.058843 (rank : 660)
Query Neighborhood Hits	872	Target Neighborhood Hits	374	Shared Neighborhood Hits	165
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

SPN90_HUMAN
θ value	θ > 10 (rank : 1111)	NC score	0.068904 (rank : 553)
Query Neighborhood Hits	872	Target Neighborhood Hits	157	Shared Neighborhood Hits	70
SwissProt Accessions	Q9NZQ3, Q9UGM8	Gene names	NCKIPSD, AF3P21, SPIN90
Domain Architecture
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (AF3p21) (Diaphanous protein-interacting protein) (Dia-interacting protein 1) (DIP-1).

SPN90_MOUSE
θ value	θ > 10 (rank : 1112)	NC score	0.057626 (rank : 675)
Query Neighborhood Hits	872	Target Neighborhood Hits	157	Shared Neighborhood Hits	59
SwissProt Accessions	Q9ESJ4, Q68G72	Gene names	Nckipsd, Spin90, Wasbp
Domain Architecture	No domain graphic available
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (N-WASP-interacting protein, 90kDa) (Wiskott-Aldrich syndrome protein-binding protein WISH) (N-WASP-binding protein).

SPR1A_MOUSE
θ value	θ > 10 (rank : 1113)	NC score	0.097911 (rank : 342)
Query Neighborhood Hits	872	Target Neighborhood Hits	343	Shared Neighborhood Hits	162
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

SPR1B_MOUSE
θ value	θ > 10 (rank : 1114)	NC score	0.132687 (rank : 234)
Query Neighborhood Hits	872	Target Neighborhood Hits	395	Shared Neighborhood Hits	192
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

SPRR3_HUMAN
θ value	θ > 10 (rank : 1115)	NC score	0.056352 (rank : 690)
Query Neighborhood Hits	872	Target Neighborhood Hits	102	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UBC9, O75597, Q4ZGI7, Q5T525, Q8NET7, Q9UDG3	Gene names	SPRR3, SPRC
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta) (Esophagin) (22 kDa pancornulin).

SPTA1_HUMAN
θ value	θ > 10 (rank : 1116)	NC score	0.058156 (rank : 670)
Query Neighborhood Hits	872	Target Neighborhood Hits	748	Shared Neighborhood Hits	129
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

SPTA1_MOUSE
θ value	θ > 10 (rank : 1117)	NC score	0.060737 (rank : 633)
Query Neighborhood Hits	872	Target Neighborhood Hits	675	Shared Neighborhood Hits	124
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

SPTA2_HUMAN
θ value	θ > 10 (rank : 1118)	NC score	0.068480 (rank : 559)
Query Neighborhood Hits	872	Target Neighborhood Hits	888	Shared Neighborhood Hits	133
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

STS2_HUMAN
θ value	θ > 10 (rank : 1119)	NC score	0.050156 (rank : 778)
Query Neighborhood Hits	872	Target Neighborhood Hits	108	Shared Neighborhood Hits	67
SwissProt Accessions	P57075, Q6HA34, Q6HA35, Q6ISI6, Q6ISK3, Q6ISS9	Gene names	UBASH3A, STS2
Domain Architecture
Description	Suppressor of T-cell receptor signaling 2 (STS-2) (Cbl-interacting protein 4) (CLIP4) (T-cell ubiquitin ligand) (TULA).

SYN2_HUMAN
θ value	θ > 10 (rank : 1120)	NC score	0.052669 (rank : 747)
Query Neighborhood Hits	872	Target Neighborhood Hits	213	Shared Neighborhood Hits	73
SwissProt Accessions	Q92777	Gene names	SYN2
Domain Architecture
Description	Synapsin-2 (Synapsin II).

SYN3_MOUSE
θ value	θ > 10 (rank : 1121)	NC score	0.051328 (rank : 765)
Query Neighborhood Hits	872	Target Neighborhood Hits	200	Shared Neighborhood Hits	72
SwissProt Accessions	Q8JZP2	Gene names	Syn3
Domain Architecture	No domain graphic available
Description	Synapsin-3 (Synapsin III).

SYNPO_HUMAN
θ value	θ > 10 (rank : 1122)	NC score	0.064429 (rank : 596)
Query Neighborhood Hits	872	Target Neighborhood Hits	281	Shared Neighborhood Hits	107
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

T22D4_HUMAN
θ value	θ > 10 (rank : 1123)	NC score	0.111074 (rank : 298)
Query Neighborhood Hits	872	Target Neighborhood Hits	403	Shared Neighborhood Hits	186
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

TARA_HUMAN
θ value	θ > 10 (rank : 1124)	NC score	0.087747 (rank : 408)
Query Neighborhood Hits	872	Target Neighborhood Hits	1626	Shared Neighborhood Hits	284
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TAU_HUMAN
θ value	θ > 10 (rank : 1125)	NC score	0.091263 (rank : 384)
Query Neighborhood Hits	872	Target Neighborhood Hits	448	Shared Neighborhood Hits	172
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TB182_HUMAN
θ value	θ > 10 (rank : 1126)	NC score	0.051056 (rank : 770)
Query Neighborhood Hits	872	Target Neighborhood Hits	414	Shared Neighborhood Hits	116
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

TCOF_MOUSE
θ value	θ > 10 (rank : 1127)	NC score	0.055643 (rank : 700)
Query Neighborhood Hits	872	Target Neighborhood Hits	471	Shared Neighborhood Hits	91
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

TENS4_HUMAN
θ value	θ > 10 (rank : 1128)	NC score	0.054666 (rank : 716)
Query Neighborhood Hits	872	Target Neighborhood Hits	214	Shared Neighborhood Hits	81
SwissProt Accessions	Q8IZW8, Q71RB7, Q8WV64, Q96JV4	Gene names	TNS4, CTEN
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor (C-terminal tensin-like protein).

TGON2_HUMAN
θ value	θ > 10 (rank : 1129)	NC score	0.072820 (rank : 521)
Query Neighborhood Hits	872	Target Neighborhood Hits	1037	Shared Neighborhood Hits	186
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TIAM1_MOUSE
θ value	θ > 10 (rank : 1130)	NC score	0.087890 (rank : 407)
Query Neighborhood Hits	872	Target Neighborhood Hits	205	Shared Neighborhood Hits	40
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

TM108_MOUSE
θ value	θ > 10 (rank : 1131)	NC score	0.071740 (rank : 530)
Query Neighborhood Hits	872	Target Neighborhood Hits	336	Shared Neighborhood Hits	121
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

TP53B_MOUSE
θ value	θ > 10 (rank : 1132)	NC score	0.055691 (rank : 699)
Query Neighborhood Hits	872	Target Neighborhood Hits	644	Shared Neighborhood Hits	130
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TPO_MOUSE
θ value	θ > 10 (rank : 1133)	NC score	0.116316 (rank : 279)
Query Neighborhood Hits	872	Target Neighborhood Hits	258	Shared Neighborhood Hits	152
SwissProt Accessions	P40226	Gene names	Thpo
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

TROAP_HUMAN
θ value	θ > 10 (rank : 1134)	NC score	0.072755 (rank : 523)
Query Neighborhood Hits	872	Target Neighborhood Hits	258	Shared Neighborhood Hits	119
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

TS13_MOUSE
θ value	θ > 10 (rank : 1135)	NC score	0.064539 (rank : 593)
Query Neighborhood Hits	872	Target Neighborhood Hits	191	Shared Neighborhood Hits	85
SwissProt Accessions	Q01755	Gene names	Tcp11
Domain Architecture
Description	Testis-specific protein PBS13.

TULP4_HUMAN
θ value	θ > 10 (rank : 1136)	NC score	0.101350 (rank : 332)
Query Neighborhood Hits	872	Target Neighborhood Hits	426	Shared Neighborhood Hits	171
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

TXND2_HUMAN
θ value	θ > 10 (rank : 1137)	NC score	0.077731 (rank : 488)
Query Neighborhood Hits	872	Target Neighborhood Hits	793	Shared Neighborhood Hits	143
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

UN13A_HUMAN
θ value	θ > 10 (rank : 1138)	NC score	0.059476 (rank : 650)
Query Neighborhood Hits	872	Target Neighborhood Hits	285	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

UN13B_HUMAN
θ value	θ > 10 (rank : 1139)	NC score	0.056882 (rank : 681)
Query Neighborhood Hits	872	Target Neighborhood Hits	217	Shared Neighborhood Hits	32
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

UN13B_MOUSE
θ value	θ > 10 (rank : 1140)	NC score	0.054166 (rank : 727)
Query Neighborhood Hits	872	Target Neighborhood Hits	210	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

ZN645_HUMAN
θ value	θ > 10 (rank : 1141)	NC score	0.086413 (rank : 420)
Query Neighborhood Hits	872	Target Neighborhood Hits	265	Shared Neighborhood Hits	110
SwissProt Accessions	Q8N7E2, Q6DJY9	Gene names	ZNF645
Domain Architecture	No domain graphic available
Description	Zinc finger protein 645.

ZN750_MOUSE
θ value	θ > 10 (rank : 1142)	NC score	0.061290 (rank : 624)
Query Neighborhood Hits	872	Target Neighborhood Hits	346	Shared Neighborhood Hits	105
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

Hits sorted by NC score

TCGAP_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	872	Target Neighborhood Hits	872	Shared Neighborhood Hits	872
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TCGAP_MOUSE
NC score	0.875877 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	872	Target Neighborhood Hits	409	Shared Neighborhood Hits	319
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

RHG09_HUMAN
NC score	0.723695 (rank : 3)	θ value	9.54697e-26 (rank : 9)
Query Neighborhood Hits	872	Target Neighborhood Hits	186	Shared Neighborhood Hits	103
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

3BP1_HUMAN
NC score	0.703298 (rank : 4)	θ value	4.9032e-22 (rank : 11)
Query Neighborhood Hits	872	Target Neighborhood Hits	376	Shared Neighborhood Hits	179
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

3BP1_MOUSE
NC score	0.700524 (rank : 5)	θ value	1.86321e-21 (rank : 12)
Query Neighborhood Hits	872	Target Neighborhood Hits	238	Shared Neighborhood Hits	116
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

RHG12_MOUSE
NC score	0.692460 (rank : 6)	θ value	7.80994e-28 (rank : 7)
Query Neighborhood Hits	872	Target Neighborhood Hits	204	Shared Neighborhood Hits	85
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RHG12_HUMAN
NC score	0.692146 (rank : 7)	θ value	5.06226e-27 (rank : 8)
Query Neighborhood Hits	872	Target Neighborhood Hits	190	Shared Neighborhood Hits	83
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

GMIP_MOUSE
NC score	0.684396 (rank : 8)	θ value	5.99374e-20 (rank : 16)
Query Neighborhood Hits	872	Target Neighborhood Hits	202	Shared Neighborhood Hits	81
SwissProt Accessions	Q6PGG2, Q6P9S3	Gene names	Gmip
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

GMIP_HUMAN
NC score	0.677516 (rank : 9)	θ value	4.29542e-18 (rank : 21)
Query Neighborhood Hits	872	Target Neighborhood Hits	225	Shared Neighborhood Hits	91
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

CHIO_MOUSE
NC score	0.675935 (rank : 10)	θ value	9.8567e-31 (rank : 5)
Query Neighborhood Hits	872	Target Neighborhood Hits	130	Shared Neighborhood Hits	72
SwissProt Accessions	Q80XD1, Q9D9W2, Q9ER57	Gene names	Chn2, Arhgap3, Bch
Domain Architecture	No domain graphic available
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

RHG04_HUMAN
NC score	0.672142 (rank : 11)	θ value	9.24701e-21 (rank : 14)
Query Neighborhood Hits	872	Target Neighborhood Hits	307	Shared Neighborhood Hits	175
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

RHG26_HUMAN
NC score	0.669469 (rank : 12)	θ value	4.58923e-20 (rank : 15)
Query Neighborhood Hits	872	Target Neighborhood Hits	281	Shared Neighborhood Hits	150
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

RGAP1_HUMAN
NC score	0.669249 (rank : 13)	θ value	6.20254e-17 (rank : 26)
Query Neighborhood Hits	872	Target Neighborhood Hits	189	Shared Neighborhood Hits	68
SwissProt Accessions	Q9H0H5, Q6PJ26, Q9NWN2, Q9P250, Q9P2W2	Gene names	RACGAP1, KIAA1478, MGCRACGAP
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RGAP1_MOUSE
NC score	0.668923 (rank : 14)	θ value	2.35696e-16 (rank : 28)
Query Neighborhood Hits	872	Target Neighborhood Hits	185	Shared Neighborhood Hits	67
SwissProt Accessions	Q9WVM1, Q3THR5, Q3TI41, Q3TM81	Gene names	Racgap1, Mgcracgap
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

CHIN_MOUSE
NC score	0.660885 (rank : 15)	θ value	1.52067e-31 (rank : 4)
Query Neighborhood Hits	872	Target Neighborhood Hits	229	Shared Neighborhood Hits	88
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIN_HUMAN
NC score	0.659995 (rank : 16)	θ value	5.22648e-32 (rank : 3)
Query Neighborhood Hits	872	Target Neighborhood Hits	227	Shared Neighborhood Hits	84
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

RHG06_HUMAN
NC score	0.659217 (rank : 17)	θ value	9.90251e-15 (rank : 33)
Query Neighborhood Hits	872	Target Neighborhood Hits	114	Shared Neighborhood Hits	77
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

CHIO_HUMAN
NC score	0.658757 (rank : 18)	θ value	3.74554e-30 (rank : 6)
Query Neighborhood Hits	872	Target Neighborhood Hits	220	Shared Neighborhood Hits	84
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

RHG06_MOUSE
NC score	0.655044 (rank : 19)	θ value	1.68911e-14 (rank : 35)
Query Neighborhood Hits	872	Target Neighborhood Hits	105	Shared Neighborhood Hits	66
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

GRLF1_HUMAN
NC score	0.648517 (rank : 20)	θ value	1.80466e-16 (rank : 27)
Query Neighborhood Hits	872	Target Neighborhood Hits	167	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

ABR_HUMAN
NC score	0.647366 (rank : 21)	θ value	6.84181e-24 (rank : 10)
Query Neighborhood Hits	872	Target Neighborhood Hits	166	Shared Neighborhood Hits	94
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

OPHN1_HUMAN
NC score	0.646828 (rank : 22)	θ value	1.13037e-18 (rank : 18)
Query Neighborhood Hits	872	Target Neighborhood Hits	161	Shared Neighborhood Hits	81
SwissProt Accessions	O60890, Q5JQ81, Q8WX47	Gene names	OPHN1
Domain Architecture
Description	Oligophrenin 1.

OPHN1_MOUSE
NC score	0.644684 (rank : 23)	θ value	3.88503e-19 (rank : 17)
Query Neighborhood Hits	872	Target Neighborhood Hits	174	Shared Neighborhood Hits	70
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

BCR_HUMAN
NC score	0.640773 (rank : 24)	θ value	5.42112e-21 (rank : 13)
Query Neighborhood Hits	872	Target Neighborhood Hits	204	Shared Neighborhood Hits	104
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

RHG01_HUMAN
NC score	0.638009 (rank : 25)	θ value	1.29331e-14 (rank : 34)
Query Neighborhood Hits	872	Target Neighborhood Hits	75	Shared Neighborhood Hits	62
SwissProt Accessions	Q07960	Gene names	ARHGAP1, CDC42GAP, RHOGAP1
Domain Architecture
Description	Rho-GTPase-activating protein 1 (GTPase-activating protein rhoOGAP) (Rho-related small GTPase protein activator) (CDC42 GTPase-activating protein) (p50-RhoGAP).

SRGP2_HUMAN
NC score	0.631064 (rank : 26)	θ value	1.86753e-13 (rank : 40)
Query Neighborhood Hits	872	Target Neighborhood Hits	331	Shared Neighborhood Hits	167
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

RHG18_HUMAN
NC score	0.630850 (rank : 27)	θ value	1.133e-10 (rank : 47)
Query Neighborhood Hits	872	Target Neighborhood Hits	90	Shared Neighborhood Hits	63
SwissProt Accessions	Q8N392, Q58EZ3, Q6P679, Q6PJD7, Q96S64	Gene names	ARHGAP18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18 (MacGAP).

SRGP2_MOUSE
NC score	0.625525 (rank : 28)	θ value	9.26847e-13 (rank : 43)
Query Neighborhood Hits	872	Target Neighborhood Hits	324	Shared Neighborhood Hits	168
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

RHG18_MOUSE
NC score	0.624974 (rank : 29)	θ value	2.52405e-10 (rank : 51)
Query Neighborhood Hits	872	Target Neighborhood Hits	110	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K0Q5, Q8BP03, Q8R196	Gene names	Arhgap18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18.

RHG08_MOUSE
NC score	0.624177 (rank : 30)	θ value	1.58096e-12 (rank : 45)
Query Neighborhood Hits	872	Target Neighborhood Hits	73	Shared Neighborhood Hits	62
SwissProt Accessions	Q9CXP4, Q99JY7	Gene names	Arhgap8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RHG08_HUMAN
NC score	0.624175 (rank : 31)	θ value	6.41864e-14 (rank : 38)
Query Neighborhood Hits	872	Target Neighborhood Hits	88	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NSG0, O75983, O95695, Q96RW1, Q96RW2, Q9HA49, Q9HC46, Q9NVX8, Q9NXL1, Q9UH20	Gene names	ARHGAP8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RHG05_MOUSE
NC score	0.622388 (rank : 32)	θ value	8.95645e-16 (rank : 30)
Query Neighborhood Hits	872	Target Neighborhood Hits	165	Shared Neighborhood Hits	71
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

SRGP1_HUMAN
NC score	0.621832 (rank : 33)	θ value	4.02038e-16 (rank : 29)
Query Neighborhood Hits	872	Target Neighborhood Hits	390	Shared Neighborhood Hits	165
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

FNBP2_HUMAN
NC score	0.619178 (rank : 34)	θ value	7.58209e-15 (rank : 32)
Query Neighborhood Hits	872	Target Neighborhood Hits	432	Shared Neighborhood Hits	177
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

RHG05_HUMAN
NC score	0.612141 (rank : 35)	θ value	4.91457e-14 (rank : 37)
Query Neighborhood Hits	872	Target Neighborhood Hits	158	Shared Neighborhood Hits	69
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

RHG25_MOUSE
NC score	0.610203 (rank : 36)	θ value	5.60996e-18 (rank : 23)
Query Neighborhood Hits	872	Target Neighborhood Hits	492	Shared Neighborhood Hits	102
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RBP1_MOUSE
NC score	0.604919 (rank : 37)	θ value	3.28887e-18 (rank : 20)
Query Neighborhood Hits	872	Target Neighborhood Hits	493	Shared Neighborhood Hits	81
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

RBP1_HUMAN
NC score	0.587201 (rank : 38)	θ value	2.7842e-17 (rank : 25)
Query Neighborhood Hits	872	Target Neighborhood Hits	521	Shared Neighborhood Hits	79
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

RHG25_HUMAN
NC score	0.584316 (rank : 39)	θ value	1.68911e-14 (rank : 36)
Query Neighborhood Hits	872	Target Neighborhood Hits	550	Shared Neighborhood Hits	94
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RHG07_MOUSE
NC score	0.565687 (rank : 40)	θ value	4.16044e-13 (rank : 41)
Query Neighborhood Hits	872	Target Neighborhood Hits	103	Shared Neighborhood Hits	63
SwissProt Accessions	Q9R0Z9, Q8R541	Gene names	Dlc1, Arhgap7, Stard12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein homolog) (Dlc-1) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

RHG07_HUMAN
NC score	0.559751 (rank : 41)	θ value	3.52202e-12 (rank : 46)
Query Neighborhood Hits	872	Target Neighborhood Hits	108	Shared Neighborhood Hits	63
SwissProt Accessions	Q96QB1, O14868, O43199, Q9C0E0	Gene names	DLC1, ARHGAP7, KIAA1723, STARD12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein) (Dlc-1) (HP protein) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

TAGAP_HUMAN
NC score	0.557328 (rank : 42)	θ value	1.17247e-07 (rank : 62)
Query Neighborhood Hits	872	Target Neighborhood Hits	82	Shared Neighborhood Hits	60
SwissProt Accessions	Q8N103, Q2NKM8, Q8NI40, Q96KZ2, Q96QA2	Gene names	TAGAP, TAGAP1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

TAGAP_MOUSE
NC score	0.557299 (rank : 43)	θ value	4.92598e-06 (rank : 72)
Query Neighborhood Hits	872	Target Neighborhood Hits	83	Shared Neighborhood Hits	61
SwissProt Accessions	Q8K2L9, Q920D6	Gene names	Tagap, Tagap1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

STAR8_HUMAN
NC score	0.533570 (rank : 44)	θ value	4.30538e-10 (rank : 52)
Query Neighborhood Hits	872	Target Neighborhood Hits	216	Shared Neighborhood Hits	103
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

CEND2_HUMAN
NC score	0.533023 (rank : 45)	θ value	1.42992e-13 (rank : 39)
Query Neighborhood Hits	872	Target Neighborhood Hits	166	Shared Neighborhood Hits	71
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

CE005_HUMAN
NC score	0.532303 (rank : 46)	θ value	5.43371e-13 (rank : 42)
Query Neighborhood Hits	872	Target Neighborhood Hits	213	Shared Neighborhood Hits	66
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

STAR8_MOUSE
NC score	0.530580 (rank : 47)	θ value	1.9326e-10 (rank : 50)
Query Neighborhood Hits	872	Target Neighborhood Hits	101	Shared Neighborhood Hits	62
SwissProt Accessions	Q8K031, Q3UZC7, Q6A0A8, Q6P5E0, Q8R3X8	Gene names	Stard8, Kiaa0189
Domain Architecture	No domain graphic available
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

CE005_MOUSE
NC score	0.528494 (rank : 48)	θ value	1.58096e-12 (rank : 44)
Query Neighborhood Hits	872	Target Neighborhood Hits	238	Shared Neighborhood Hits	65
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

STA13_HUMAN
NC score	0.524386 (rank : 49)	θ value	1.133e-10 (rank : 48)
Query Neighborhood Hits	872	Target Neighborhood Hits	89	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y3M8, Q5HYH1, Q5TAE3, Q6UN61, Q86TP6, Q86WQ3, Q86XT1	Gene names	STARD13, DLC2, GT650
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13) (46H23.2) (Deleted in liver cancer protein 2) (Rho GTPase-activating protein).

STA13_MOUSE
NC score	0.515776 (rank : 50)	θ value	5.62301e-10 (rank : 53)
Query Neighborhood Hits	872	Target Neighborhood Hits	89	Shared Neighborhood Hits	59
SwissProt Accessions	Q923Q2, Q8K369	Gene names	Stard13
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13).

CEND3_HUMAN
NC score	0.514406 (rank : 51)	θ value	2.7842e-17 (rank : 24)
Query Neighborhood Hits	872	Target Neighborhood Hits	275	Shared Neighborhood Hits	107
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

CEND3_MOUSE
NC score	0.513004 (rank : 52)	θ value	7.58209e-15 (rank : 31)
Query Neighborhood Hits	872	Target Neighborhood Hits	228	Shared Neighborhood Hits	85
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

K1688_HUMAN
NC score	0.502977 (rank : 53)	θ value	3.64472e-09 (rank : 57)
Query Neighborhood Hits	872	Target Neighborhood Hits	217	Shared Neighborhood Hits	120
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

K1688_MOUSE
NC score	0.497836 (rank : 54)	θ value	2.13673e-09 (rank : 55)
Query Neighborhood Hits	872	Target Neighborhood Hits	188	Shared Neighborhood Hits	103
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

CEND1_MOUSE
NC score	0.455514 (rank : 55)	θ value	1.63604e-09 (rank : 54)
Query Neighborhood Hits	872	Target Neighborhood Hits	260	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

CEND1_HUMAN
NC score	0.439657 (rank : 56)	θ value	2.79066e-09 (rank : 56)
Query Neighborhood Hits	872	Target Neighborhood Hits	284	Shared Neighborhood Hits	73
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

MYO9B_HUMAN
NC score	0.375159 (rank : 57)	θ value	1.92812e-18 (rank : 19)
Query Neighborhood Hits	872	Target Neighborhood Hits	641	Shared Neighborhood Hits	181
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

P85A_HUMAN
NC score	0.368231 (rank : 58)	θ value	3.08544e-08 (rank : 59)
Query Neighborhood Hits	872	Target Neighborhood Hits	479	Shared Neighborhood Hits	123
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

MYO9B_MOUSE
NC score	0.364728 (rank : 59)	θ value	5.60996e-18 (rank : 22)
Query Neighborhood Hits	872	Target Neighborhood Hits	311	Shared Neighborhood Hits	93
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

P85A_MOUSE
NC score	0.363922 (rank : 60)	θ value	1.17247e-07 (rank : 61)
Query Neighborhood Hits	872	Target Neighborhood Hits	435	Shared Neighborhood Hits	124
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

I5P2_HUMAN
NC score	0.307655 (rank : 61)	θ value	9.29e-05 (rank : 87)
Query Neighborhood Hits	872	Target Neighborhood Hits	86	Shared Neighborhood Hits	59
SwissProt Accessions	P32019, Q5VSG9, Q5VSH0, Q5VSH1, Q658Q5, Q6P6D4, Q6PD53, Q86YE1	Gene names	INPP5B
Domain Architecture	No domain graphic available
Description	Type II inositol-1,4,5-trisphosphate 5-phosphatase precursor (EC 3.1.3.36) (Phosphoinositide 5-phosphatase) (5PTase) (75 kDa inositol polyphosphate-5-phosphatase).

MUC1_HUMAN
NC score	0.303480 (rank : 62)	θ value	1.9326e-10 (rank : 49)
Query Neighborhood Hits	872	Target Neighborhood Hits	975	Shared Neighborhood Hits	389
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

OCRL_HUMAN
NC score	0.300028 (rank : 63)	θ value	9.29e-05 (rank : 88)
Query Neighborhood Hits	872	Target Neighborhood Hits	77	Shared Neighborhood Hits	58
SwissProt Accessions	Q01968, O60800, Q15684, Q15774, Q5JQF1, Q5JQF2, Q9UJG5, Q9UMA5	Gene names	OCRL, INPP5F, OCRL1
Domain Architecture
Description	Inositol polyphosphate 5-phosphatase OCRL-1 (EC 3.1.3.36) (Lowe oculocerebrorenal syndrome protein).

PRRT3_HUMAN
NC score	0.273840 (rank : 64)	θ value	6.88961 (rank : 786)
Query Neighborhood Hits	872	Target Neighborhood Hits	998	Shared Neighborhood Hits	414
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

OGFR_HUMAN
NC score	0.268964 (rank : 65)	θ value	0.62314 (rank : 442)
Query Neighborhood Hits	872	Target Neighborhood Hits	1582	Shared Neighborhood Hits	496
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

BCL9_HUMAN
NC score	0.261874 (rank : 66)	θ value	0.0961366 (rank : 304)
Query Neighborhood Hits	872	Target Neighborhood Hits	1008	Shared Neighborhood Hits	417
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

HCLS1_HUMAN
NC score	0.257307 (rank : 67)	θ value	0.00134147 (rank : 134)
Query Neighborhood Hits	872	Target Neighborhood Hits	358	Shared Neighborhood Hits	201
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

BCAR1_HUMAN
NC score	0.248133 (rank : 68)	θ value	0.00298849 (rank : 150)
Query Neighborhood Hits	872	Target Neighborhood Hits	554	Shared Neighborhood Hits	300
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

IASPP_MOUSE
NC score	0.245350 (rank : 69)	θ value	0.0193708 (rank : 227)
Query Neighborhood Hits	872	Target Neighborhood Hits	1024	Shared Neighborhood Hits	413
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

SSBP4_HUMAN
NC score	0.244849 (rank : 70)	θ value	0.0252991 (rank : 244)
Query Neighborhood Hits	872	Target Neighborhood Hits	753	Shared Neighborhood Hits	370
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

HCLS1_MOUSE
NC score	0.243088 (rank : 71)	θ value	0.00298849 (rank : 152)
Query Neighborhood Hits	872	Target Neighborhood Hits	329	Shared Neighborhood Hits	170
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

CD2AP_HUMAN
NC score	0.240759 (rank : 72)	θ value	0.00102713 (rank : 123)
Query Neighborhood Hits	872	Target Neighborhood Hits	315	Shared Neighborhood Hits	136
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

MISS_MOUSE
NC score	0.239672 (rank : 73)	θ value	0.0563607 (rank : 280)
Query Neighborhood Hits	872	Target Neighborhood Hits	444	Shared Neighborhood Hits	261
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

CD2AP_MOUSE
NC score	0.238132 (rank : 74)	θ value	0.00102713 (rank : 124)
Query Neighborhood Hits	872	Target Neighborhood Hits	336	Shared Neighborhood Hits	147
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

NCOA6_HUMAN
NC score	0.238108 (rank : 75)	θ value	0.0113563 (rank : 204)
Query Neighborhood Hits	872	Target Neighborhood Hits	1202	Shared Neighborhood Hits	420
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

SH3K1_MOUSE
NC score	0.237182 (rank : 76)	θ value	0.0113563 (rank : 206)
Query Neighborhood Hits	872	Target Neighborhood Hits	332	Shared Neighborhood Hits	144
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

SH3K1_HUMAN
NC score	0.236890 (rank : 77)	θ value	0.0148317 (rank : 217)
Query Neighborhood Hits	872	Target Neighborhood Hits	341	Shared Neighborhood Hits	141
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

SC24C_HUMAN
NC score	0.236196 (rank : 78)	θ value	0.00035302 (rank : 109)
Query Neighborhood Hits	872	Target Neighborhood Hits	662	Shared Neighborhood Hits	330
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

SON_HUMAN
NC score	0.234721 (rank : 79)	θ value	θ > 10 (rank : 1106)
Query Neighborhood Hits	872	Target Neighborhood Hits	1568	Shared Neighborhood Hits	484
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

STAC3_MOUSE
NC score	0.225484 (rank : 80)	θ value	0.00102713 (rank : 130)
Query Neighborhood Hits	872	Target Neighborhood Hits	232	Shared Neighborhood Hits	112
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

BCAR1_MOUSE
NC score	0.225368 (rank : 81)	θ value	0.00035302 (rank : 107)
Query Neighborhood Hits	872	Target Neighborhood Hits	438	Shared Neighborhood Hits	251
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

STAC3_HUMAN
NC score	0.224705 (rank : 82)	θ value	0.00102713 (rank : 129)
Query Neighborhood Hits	872	Target Neighborhood Hits	228	Shared Neighborhood Hits	113
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

RGS3_MOUSE
NC score	0.221747 (rank : 83)	θ value	0.0736092 (rank : 297)
Query Neighborhood Hits	872	Target Neighborhood Hits	1621	Shared Neighborhood Hits	497
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

GRAP_HUMAN
NC score	0.220988 (rank : 84)	θ value	7.59969e-07 (rank : 64)
Query Neighborhood Hits	872	Target Neighborhood Hits	307	Shared Neighborhood Hits	143
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

SRC8_MOUSE
NC score	0.219473 (rank : 85)	θ value	0.000786445 (rank : 122)
Query Neighborhood Hits	872	Target Neighborhood Hits	292	Shared Neighborhood Hits	128
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

ABI2_HUMAN
NC score	0.218305 (rank : 86)	θ value	0.21417 (rank : 357)
Query Neighborhood Hits	872	Target Neighborhood Hits	350	Shared Neighborhood Hits	176
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

STAC_MOUSE
NC score	0.218230 (rank : 87)	θ value	0.0431538 (rank : 269)
Query Neighborhood Hits	872	Target Neighborhood Hits	268	Shared Neighborhood Hits	127
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

GRAP_MOUSE
NC score	0.217296 (rank : 88)	θ value	2.88788e-06 (rank : 70)
Query Neighborhood Hits	872	Target Neighborhood Hits	309	Shared Neighborhood Hits	141
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

STAC_HUMAN
NC score	0.215944 (rank : 89)	θ value	0.0563607 (rank : 285)
Query Neighborhood Hits	872	Target Neighborhood Hits	276	Shared Neighborhood Hits	124
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

BCL9_MOUSE
NC score	0.213808 (rank : 90)	θ value	0.163984 (rank : 333)
Query Neighborhood Hits	872	Target Neighborhood Hits	770	Shared Neighborhood Hits	349
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

VINEX_MOUSE
NC score	0.213793 (rank : 91)	θ value	0.0736092 (rank : 300)
Query Neighborhood Hits	872	Target Neighborhood Hits	286	Shared Neighborhood Hits	144
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

SRC8_HUMAN
NC score	0.213046 (rank : 92)	θ value	0.00509761 (rank : 175)
Query Neighborhood Hits	872	Target Neighborhood Hits	269	Shared Neighborhood Hits	118
SwissProt Accessions	Q14247	Gene names	CTTN, EMS1
Domain Architecture
Description	Src substrate cortactin (Amplaxin) (Oncogene EMS1).

NACAM_MOUSE
NC score	0.212397 (rank : 93)	θ value	8.99809 (rank : 844)
Query Neighborhood Hits	872	Target Neighborhood Hits	1866	Shared Neighborhood Hits	472
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NCF2_HUMAN
NC score	0.212084 (rank : 94)	θ value	0.813845 (rank : 465)
Query Neighborhood Hits	872	Target Neighborhood Hits	229	Shared Neighborhood Hits	124
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

ABI2_MOUSE
NC score	0.207681 (rank : 95)	θ value	0.0252991 (rank : 235)
Query Neighborhood Hits	872	Target Neighborhood Hits	266	Shared Neighborhood Hits	142
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

SRBS1_MOUSE
NC score	0.207679 (rank : 96)	θ value	2.36792 (rank : 623)
Query Neighborhood Hits	872	Target Neighborhood Hits	409	Shared Neighborhood Hits	176
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

NCK2_HUMAN
NC score	0.207427 (rank : 97)	θ value	0.0148317 (rank : 212)
Query Neighborhood Hits	872	Target Neighborhood Hits	310	Shared Neighborhood Hits	134
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

VINEX_HUMAN
NC score	0.206932 (rank : 98)	θ value	0.163984 (rank : 355)
Query Neighborhood Hits	872	Target Neighborhood Hits	270	Shared Neighborhood Hits	141
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

GRB2_HUMAN
NC score	0.203802 (rank : 99)	θ value	0.163984 (rank : 339)
Query Neighborhood Hits	872	Target Neighborhood Hits	310	Shared Neighborhood Hits	136
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
NC score	0.203568 (rank : 100)	θ value	0.163984 (rank : 340)
Query Neighborhood Hits	872	Target Neighborhood Hits	312	Shared Neighborhood Hits	136
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

GRAP2_HUMAN
NC score	0.202464 (rank : 101)	θ value	0.0252991 (rank : 239)
Query Neighborhood Hits	872	Target Neighborhood Hits	304	Shared Neighborhood Hits	138
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

SRBS1_HUMAN
NC score	0.201679 (rank : 102)	θ value	1.38821 (rank : 549)
Query Neighborhood Hits	872	Target Neighborhood Hits	396	Shared Neighborhood Hits	163
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

GRAP2_MOUSE
NC score	0.201163 (rank : 103)	θ value	0.0330416 (rank : 251)
Query Neighborhood Hits	872	Target Neighborhood Hits	297	Shared Neighborhood Hits	137
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

ARHG7_MOUSE
NC score	0.200787 (rank : 104)	θ value	0.0148317 (rank : 208)
Query Neighborhood Hits	872	Target Neighborhood Hits	396	Shared Neighborhood Hits	135
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

ABI1_MOUSE
NC score	0.200248 (rank : 105)	θ value	0.00298849 (rank : 149)
Query Neighborhood Hits	872	Target Neighborhood Hits	246	Shared Neighborhood Hits	144
SwissProt Accessions	Q8CBW3, Q60747, Q91ZM5, Q923I9, Q99KH4	Gene names	Abi1, Ssh3bp1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Ablphilin-1).

MAGE1_HUMAN
NC score	0.199240 (rank : 106)	θ value	θ > 10 (rank : 1029)
Query Neighborhood Hits	872	Target Neighborhood Hits	1389	Shared Neighborhood Hits	437
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

STAM1_HUMAN
NC score	0.198330 (rank : 107)	θ value	0.0113563 (rank : 207)
Query Neighborhood Hits	872	Target Neighborhood Hits	271	Shared Neighborhood Hits	134
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

BSN_MOUSE
NC score	0.198218 (rank : 108)	θ value	0.0193708 (rank : 222)
Query Neighborhood Hits	872	Target Neighborhood Hits	2057	Shared Neighborhood Hits	480
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

DNMBP_HUMAN
NC score	0.198187 (rank : 109)	θ value	0.0148317 (rank : 209)
Query Neighborhood Hits	872	Target Neighborhood Hits	413	Shared Neighborhood Hits	149
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

STAM1_MOUSE
NC score	0.197654 (rank : 110)	θ value	0.00869519 (rank : 193)
Query Neighborhood Hits	872	Target Neighborhood Hits	273	Shared Neighborhood Hits	134
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

DNMBP_MOUSE
NC score	0.196510 (rank : 111)	θ value	0.0563607 (rank : 278)
Query Neighborhood Hits	872	Target Neighborhood Hits	435	Shared Neighborhood Hits	159
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

NCOA6_MOUSE
NC score	0.196350 (rank : 112)	θ value	8.99809 (rank : 847)
Query Neighborhood Hits	872	Target Neighborhood Hits	1076	Shared Neighborhood Hits	376
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

ARHG7_HUMAN
NC score	0.195541 (rank : 113)	θ value	0.0330416 (rank : 248)
Query Neighborhood Hits	872	Target Neighborhood Hits	347	Shared Neighborhood Hits	137
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

BAT2_HUMAN
NC score	0.194958 (rank : 114)	θ value	0.000158464 (rank : 90)
Query Neighborhood Hits	872	Target Neighborhood Hits	931	Shared Neighborhood Hits	307
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

NCK1_HUMAN
NC score	0.194766 (rank : 115)	θ value	0.0193708 (rank : 229)
Query Neighborhood Hits	872	Target Neighborhood Hits	312	Shared Neighborhood Hits	131
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

STAM2_MOUSE
NC score	0.194096 (rank : 116)	θ value	0.00298849 (rank : 156)
Query Neighborhood Hits	872	Target Neighborhood Hits	285	Shared Neighborhood Hits	135
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

STAM2_HUMAN
NC score	0.193445 (rank : 117)	θ value	0.00228821 (rank : 147)
Query Neighborhood Hits	872	Target Neighborhood Hits	288	Shared Neighborhood Hits	135
SwissProt Accessions	O75886, Q7LDQ0, Q9UF58	Gene names	STAM2
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2).

ABI1_HUMAN
NC score	0.193288 (rank : 118)	θ value	0.0961366 (rank : 302)
Query Neighborhood Hits	872	Target Neighborhood Hits	257	Shared Neighborhood Hits	153
SwissProt Accessions	Q8IZP0, O15147, O76049, O95060, Q5W070, Q5W072, Q8TB63, Q96S81, Q9NXZ9, Q9NYB8	Gene names	ABI1, SSH3BP1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Nap1-binding protein) (Nap1BP) (Abl-binding protein 4) (AblBP4).

PCLO_MOUSE
NC score	0.191947 (rank : 119)	θ value	0.000602161 (rank : 116)
Query Neighborhood Hits	872	Target Neighborhood Hits	2275	Shared Neighborhood Hits	510
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

CEL_HUMAN
NC score	0.191885 (rank : 120)	θ value	θ > 10 (rank : 915)
Query Neighborhood Hits	872	Target Neighborhood Hits	896	Shared Neighborhood Hits	387
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

BAT2_MOUSE
NC score	0.190965 (rank : 121)	θ value	0.00020696 (rank : 96)
Query Neighborhood Hits	872	Target Neighborhood Hits	947	Shared Neighborhood Hits	317
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

ARHG4_HUMAN
NC score	0.188331 (rank : 122)	θ value	0.000270298 (rank : 102)
Query Neighborhood Hits	872	Target Neighborhood Hits	242	Shared Neighborhood Hits	125
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ARHG9_MOUSE
NC score	0.187706 (rank : 123)	θ value	0.00509761 (rank : 168)
Query Neighborhood Hits	872	Target Neighborhood Hits	234	Shared Neighborhood Hits	127
SwissProt Accessions	Q3UTH8, Q3TQ60, Q80U06, Q8CAF9	Gene names	Arhgef9, Kiaa0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin).

ARHG9_HUMAN
NC score	0.187507 (rank : 124)	θ value	0.00509761 (rank : 167)
Query Neighborhood Hits	872	Target Neighborhood Hits	235	Shared Neighborhood Hits	129
SwissProt Accessions	O43307, Q5JSL6	Gene names	ARHGEF9, KIAA0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin) (PEM-2 homolog).

ITSN1_HUMAN
NC score	0.186031 (rank : 125)	θ value	2.21117e-06 (rank : 67)
Query Neighborhood Hits	872	Target Neighborhood Hits	1757	Shared Neighborhood Hits	285
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

PPIP1_HUMAN
NC score	0.185067 (rank : 126)	θ value	0.00869519 (rank : 191)
Query Neighborhood Hits	872	Target Neighborhood Hits	389	Shared Neighborhood Hits	128
SwissProt Accessions	O43586, O43585, O95657	Gene names	PSTPIP1, CD2BP1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP).

ZIM10_HUMAN
NC score	0.184556 (rank : 127)	θ value	0.0148317 (rank : 220)
Query Neighborhood Hits	872	Target Neighborhood Hits	577	Shared Neighborhood Hits	287
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

EFS_MOUSE
NC score	0.184311 (rank : 128)	θ value	8.99809 (rank : 822)
Query Neighborhood Hits	872	Target Neighborhood Hits	389	Shared Neighborhood Hits	215
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

ARHG6_MOUSE
NC score	0.184203 (rank : 129)	θ value	0.0563607 (rank : 273)
Query Neighborhood Hits	872	Target Neighborhood Hits	394	Shared Neighborhood Hits	129
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

PRP2_MOUSE
NC score	0.183809 (rank : 130)	θ value	1.87187e-05 (rank : 80)
Query Neighborhood Hits	872	Target Neighborhood Hits	347	Shared Neighborhood Hits	132
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

VAV2_MOUSE
NC score	0.183384 (rank : 131)	θ value	0.0330416 (rank : 256)
Query Neighborhood Hits	872	Target Neighborhood Hits	456	Shared Neighborhood Hits	159
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

PI5PA_HUMAN
NC score	0.182200 (rank : 132)	θ value	0.813845 (rank : 470)
Query Neighborhood Hits	872	Target Neighborhood Hits	749	Shared Neighborhood Hits	333
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

ITSN1_MOUSE
NC score	0.181495 (rank : 133)	θ value	5.81887e-07 (rank : 63)
Query Neighborhood Hits	872	Target Neighborhood Hits	1669	Shared Neighborhood Hits	249
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

VAV_MOUSE
NC score	0.180144 (rank : 134)	θ value	0.0563607 (rank : 287)
Query Neighborhood Hits	872	Target Neighborhood Hits	430	Shared Neighborhood Hits	140
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

VAV2_HUMAN
NC score	0.179803 (rank : 135)	θ value	0.0431538 (rank : 271)
Query Neighborhood Hits	872	Target Neighborhood Hits	453	Shared Neighborhood Hits	145
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

PPIP1_MOUSE
NC score	0.177444 (rank : 136)	θ value	0.0563607 (rank : 281)
Query Neighborhood Hits	872	Target Neighborhood Hits	377	Shared Neighborhood Hits	128
SwissProt Accessions	P97814, Q4V9R4	Gene names	Pstpip1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1).

ARHG6_HUMAN
NC score	0.176997 (rank : 137)	θ value	1.06291 (rank : 484)
Query Neighborhood Hits	872	Target Neighborhood Hits	376	Shared Neighborhood Hits	128
SwissProt Accessions	Q15052, Q15396, Q5JQ66, Q86XH0	Gene names	ARHGEF6, COOL2, KIAA0006, PIXA
Domain Architecture
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).

TAF4_HUMAN
NC score	0.176831 (rank : 138)	θ value	4.76016e-09 (rank : 58)
Query Neighborhood Hits	872	Target Neighborhood Hits	687	Shared Neighborhood Hits	183
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

VAV_HUMAN
NC score	0.176622 (rank : 139)	θ value	0.0563607 (rank : 286)
Query Neighborhood Hits	872	Target Neighborhood Hits	452	Shared Neighborhood Hits	140
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

VAV3_HUMAN
NC score	0.176132 (rank : 140)	θ value	0.279714 (rank : 385)
Query Neighborhood Hits	872	Target Neighborhood Hits	398	Shared Neighborhood Hits	135
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

ASPP1_MOUSE
NC score	0.176042 (rank : 141)	θ value	0.00390308 (rank : 159)
Query Neighborhood Hits	872	Target Neighborhood Hits	1244	Shared Neighborhood Hits	312
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

CN032_MOUSE
NC score	0.174672 (rank : 142)	θ value	4.1701e-05 (rank : 83)
Query Neighborhood Hits	872	Target Neighborhood Hits	233	Shared Neighborhood Hits	110
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

VAV3_MOUSE
NC score	0.174417 (rank : 143)	θ value	0.47712 (rank : 424)
Query Neighborhood Hits	872	Target Neighborhood Hits	404	Shared Neighborhood Hits	137
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

CT032_HUMAN
NC score	0.173346 (rank : 144)	θ value	0.0563607 (rank : 277)
Query Neighborhood Hits	872	Target Neighborhood Hits	235	Shared Neighborhood Hits	127
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

ITSN2_HUMAN
NC score	0.172305 (rank : 145)	θ value	0.00134147 (rank : 135)
Query Neighborhood Hits	872	Target Neighborhood Hits	1173	Shared Neighborhood Hits	178
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

MLL3_HUMAN
NC score	0.172278 (rank : 146)	θ value	0.125558 (rank : 321)
Query Neighborhood Hits	872	Target Neighborhood Hits	1644	Shared Neighborhood Hits	400
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

NCF4_MOUSE
NC score	0.172246 (rank : 147)	θ value	8.99809 (rank : 846)
Query Neighborhood Hits	872	Target Neighborhood Hits	177	Shared Neighborhood Hits	109
SwissProt Accessions	P97369	Gene names	Ncf4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

DIDO1_HUMAN
NC score	0.170653 (rank : 148)	θ value	0.47712 (rank : 404)
Query Neighborhood Hits	872	Target Neighborhood Hits	960	Shared Neighborhood Hits	295
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

K1802_MOUSE
NC score	0.170377 (rank : 149)	θ value	0.00509761 (rank : 171)
Query Neighborhood Hits	872	Target Neighborhood Hits	1596	Shared Neighborhood Hits	374
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

SH3G2_MOUSE
NC score	0.169524 (rank : 150)	θ value	0.47712 (rank : 421)
Query Neighborhood Hits	872	Target Neighborhood Hits	319	Shared Neighborhood Hits	130
SwissProt Accessions	Q62420	Gene names	Sh3gl2, Sh3d2a
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (SH3p4).

CN032_HUMAN
NC score	0.169479 (rank : 151)	θ value	0.000461057 (rank : 111)
Query Neighborhood Hits	872	Target Neighborhood Hits	267	Shared Neighborhood Hits	117
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

CPSF6_HUMAN
NC score	0.168562 (rank : 152)	θ value	1.69304e-06 (rank : 66)
Query Neighborhood Hits	872	Target Neighborhood Hits	359	Shared Neighborhood Hits	140
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

IASPP_HUMAN
NC score	0.168546 (rank : 153)	θ value	0.00665767 (rank : 181)
Query Neighborhood Hits	872	Target Neighborhood Hits	688	Shared Neighborhood Hits	216
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

CPSF6_MOUSE
NC score	0.168406 (rank : 154)	θ value	2.88788e-06 (rank : 69)
Query Neighborhood Hits	872	Target Neighborhood Hits	356	Shared Neighborhood Hits	141
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

RGS3_HUMAN
NC score	0.168394 (rank : 155)	θ value	0.813845 (rank : 471)
Query Neighborhood Hits	872	Target Neighborhood Hits	1375	Shared Neighborhood Hits	422
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

WASIP_MOUSE
NC score	0.167145 (rank : 156)	θ value	0.00020696 (rank : 101)
Query Neighborhood Hits	872	Target Neighborhood Hits	392	Shared Neighborhood Hits	163
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

OSTF1_HUMAN
NC score	0.166190 (rank : 157)	θ value	0.00228821 (rank : 145)
Query Neighborhood Hits	872	Target Neighborhood Hits	466	Shared Neighborhood Hits	134
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

CRKL_HUMAN
NC score	0.165699 (rank : 158)	θ value	1.06291 (rank : 490)
Query Neighborhood Hits	872	Target Neighborhood Hits	313	Shared Neighborhood Hits	136
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

ITSN2_MOUSE
NC score	0.165527 (rank : 159)	θ value	0.00175202 (rank : 137)
Query Neighborhood Hits	872	Target Neighborhood Hits	1371	Shared Neighborhood Hits	187
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

ZN385_HUMAN
NC score	0.165333 (rank : 160)	θ value	3.0926 (rank : 668)
Query Neighborhood Hits	872	Target Neighborhood Hits	614	Shared Neighborhood Hits	270
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

WASIP_HUMAN
NC score	0.165004 (rank : 161)	θ value	0.000461057 (rank : 114)
Query Neighborhood Hits	872	Target Neighborhood Hits	458	Shared Neighborhood Hits	161
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

SH3G2_HUMAN
NC score	0.164830 (rank : 162)	θ value	2.36792 (rank : 618)
Query Neighborhood Hits	872	Target Neighborhood Hits	324	Shared Neighborhood Hits	126
SwissProt Accessions	Q99962, Q9NQK5	Gene names	SH3GL2, CNSA2, SH3D2A
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (EEN-B1).

EFS_HUMAN
NC score	0.164272 (rank : 163)	θ value	3.0926 (rank : 640)
Query Neighborhood Hits	872	Target Neighborhood Hits	348	Shared Neighborhood Hits	192
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

NCF4_HUMAN
NC score	0.164057 (rank : 164)	θ value	θ > 10 (rank : 1048)
Query Neighborhood Hits	872	Target Neighborhood Hits	161	Shared Neighborhood Hits	101
SwissProt Accessions	Q15080, O60808, Q86U56, Q9BU98, Q9NP45	Gene names	NCF4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

OSTF1_MOUSE
NC score	0.164024 (rank : 165)	θ value	0.00175202 (rank : 138)
Query Neighborhood Hits	872	Target Neighborhood Hits	467	Shared Neighborhood Hits	134
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

ARI1A_HUMAN
NC score	0.162326 (rank : 166)	θ value	0.125558 (rank : 317)
Query Neighborhood Hits	872	Target Neighborhood Hits	787	Shared Neighborhood Hits	276
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

ABI3_MOUSE
NC score	0.161753 (rank : 167)	θ value	4.03905 (rank : 669)
Query Neighborhood Hits	872	Target Neighborhood Hits	227	Shared Neighborhood Hits	134
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

ZIMP7_MOUSE
NC score	0.161112 (rank : 168)	θ value	6.88961 (rank : 801)
Query Neighborhood Hits	872	Target Neighborhood Hits	566	Shared Neighborhood Hits	295
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

NCF1_MOUSE
NC score	0.160976 (rank : 169)	θ value	1.81305 (rank : 572)
Query Neighborhood Hits	872	Target Neighborhood Hits	198	Shared Neighborhood Hits	110
SwissProt Accessions	Q09014, O70144, Q9JI34	Gene names	Ncf1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K).

SH3G1_HUMAN
NC score	0.160877 (rank : 170)	θ value	1.06291 (rank : 511)
Query Neighborhood Hits	872	Target Neighborhood Hits	307	Shared Neighborhood Hits	126
SwissProt Accessions	Q99961, Q99668	Gene names	SH3GL1, CNSA1, SH3D2B
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL).

GSCR1_HUMAN
NC score	0.160385 (rank : 171)	θ value	7.1131e-05 (rank : 86)
Query Neighborhood Hits	872	Target Neighborhood Hits	674	Shared Neighborhood Hits	232
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

SH3G3_MOUSE
NC score	0.159309 (rank : 172)	θ value	1.81305 (rank : 583)
Query Neighborhood Hits	872	Target Neighborhood Hits	236	Shared Neighborhood Hits	120
SwissProt Accessions	Q62421	Gene names	Sh3gl3, Sh3d2c, Sh3d2c2
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (SH3p13).

SH3G1_MOUSE
NC score	0.158677 (rank : 173)	θ value	4.03905 (rank : 695)
Query Neighborhood Hits	872	Target Neighborhood Hits	291	Shared Neighborhood Hits	124
SwissProt Accessions	Q62419	Gene names	Sh3gl1, Sh3d2b
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (SH3p8).

SH3G3_HUMAN
NC score	0.158416 (rank : 174)	θ value	2.36792 (rank : 619)
Query Neighborhood Hits	872	Target Neighborhood Hits	222	Shared Neighborhood Hits	116
SwissProt Accessions	Q99963, O43553, O43554	Gene names	SH3GL3, CNSA3, SH3D2C
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (EEN-B2).

CIC_HUMAN
NC score	0.157450 (rank : 175)	θ value	0.0330416 (rank : 249)
Query Neighborhood Hits	872	Target Neighborhood Hits	992	Shared Neighborhood Hits	346
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

ARHG4_MOUSE
NC score	0.157439 (rank : 176)	θ value	0.0563607 (rank : 272)
Query Neighborhood Hits	872	Target Neighborhood Hits	185	Shared Neighborhood Hits	101
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

LPP_HUMAN
NC score	0.157274 (rank : 177)	θ value	8.99809 (rank : 839)
Query Neighborhood Hits	872	Target Neighborhood Hits	775	Shared Neighborhood Hits	308
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

CRKL_MOUSE
NC score	0.157122 (rank : 178)	θ value	1.81305 (rank : 562)
Query Neighborhood Hits	872	Target Neighborhood Hits	307	Shared Neighborhood Hits	130
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

SF3A2_HUMAN
NC score	0.156948 (rank : 179)	θ value	2.44474e-05 (rank : 82)
Query Neighborhood Hits	872	Target Neighborhood Hits	263	Shared Neighborhood Hits	105
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

ABI3_HUMAN
NC score	0.156740 (rank : 180)	θ value	8.99809 (rank : 802)
Query Neighborhood Hits	872	Target Neighborhood Hits	227	Shared Neighborhood Hits	124
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

PRP1_HUMAN
NC score	0.156219 (rank : 181)	θ value	0.00175202 (rank : 139)
Query Neighborhood Hits	872	Target Neighborhood Hits	385	Shared Neighborhood Hits	150
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

CBP_MOUSE
NC score	0.156068 (rank : 182)	θ value	0.0431538 (rank : 259)
Query Neighborhood Hits	872	Target Neighborhood Hits	1051	Shared Neighborhood Hits	333
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

PCLO_HUMAN
NC score	0.155089 (rank : 183)	θ value	0.00390308 (rank : 163)
Query Neighborhood Hits	872	Target Neighborhood Hits	2046	Shared Neighborhood Hits	401
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

SF3A2_MOUSE
NC score	0.154813 (rank : 184)	θ value	1.43324e-05 (rank : 79)
Query Neighborhood Hits	872	Target Neighborhood Hits	247	Shared Neighborhood Hits	97
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

LCP2_HUMAN
NC score	0.154656 (rank : 185)	θ value	θ > 10 (rank : 1027)
Query Neighborhood Hits	872	Target Neighborhood Hits	531	Shared Neighborhood Hits	216
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

WIRE_MOUSE
NC score	0.154570 (rank : 186)	θ value	0.000270298 (rank : 105)
Query Neighborhood Hits	872	Target Neighborhood Hits	310	Shared Neighborhood Hits	120
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

MDC1_MOUSE
NC score	0.153365 (rank : 187)	θ value	θ > 10 (rank : 1041)
Query Neighborhood Hits	872	Target Neighborhood Hits	998	Shared Neighborhood Hits	269
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

WIRE_HUMAN
NC score	0.153096 (rank : 188)	θ value	0.000158464 (rank : 95)
Query Neighborhood Hits	872	Target Neighborhood Hits	329	Shared Neighborhood Hits	116
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

PACN2_HUMAN
NC score	0.152164 (rank : 189)	θ value	0.813845 (rank : 467)
Query Neighborhood Hits	872	Target Neighborhood Hits	339	Shared Neighborhood Hits	125
SwissProt Accessions	Q9UNF0, O95921, Q96HV9, Q9H0D3, Q9NPN1, Q9Y4V2	Gene names	PACSIN2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

MBD6_HUMAN
NC score	0.151504 (rank : 190)	θ value	0.000158464 (rank : 94)
Query Neighborhood Hits	872	Target Neighborhood Hits	349	Shared Neighborhood Hits	125
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

TARSH_HUMAN
NC score	0.151457 (rank : 191)	θ value	4.03905 (rank : 698)
Query Neighborhood Hits	872	Target Neighborhood Hits	768	Shared Neighborhood Hits	261
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

MLL3_MOUSE
NC score	0.151446 (rank : 192)	θ value	θ > 10 (rank : 1042)
Query Neighborhood Hits	872	Target Neighborhood Hits	1399	Shared Neighborhood Hits	350
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

NCF1_HUMAN
NC score	0.151005 (rank : 193)	θ value	8.99809 (rank : 845)
Query Neighborhood Hits	872	Target Neighborhood Hits	198	Shared Neighborhood Hits	112
SwissProt Accessions	P14598, O43842, Q2PP07, Q9BU90, Q9BXI7, Q9BXI8, Q9UDV9, Q9UMU2	Gene names	NCF1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDa autosomal chronic granulomatous disease protein) (NOXO2).

MDC1_HUMAN
NC score	0.150144 (rank : 194)	θ value	θ > 10 (rank : 1040)
Query Neighborhood Hits	872	Target Neighborhood Hits	1446	Shared Neighborhood Hits	291
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

PACN2_MOUSE
NC score	0.149806 (rank : 195)	θ value	0.813845 (rank : 468)
Query Neighborhood Hits	872	Target Neighborhood Hits	382	Shared Neighborhood Hits	133
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

CECR2_HUMAN
NC score	0.147612 (rank : 196)	θ value	θ > 10 (rank : 914)
Query Neighborhood Hits	872	Target Neighborhood Hits	543	Shared Neighborhood Hits	254
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

CD2_HUMAN
NC score	0.147432 (rank : 197)	θ value	θ > 10 (rank : 912)
Query Neighborhood Hits	872	Target Neighborhood Hits	504	Shared Neighborhood Hits	230
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

PACN1_MOUSE
NC score	0.147390 (rank : 198)	θ value	1.81305 (rank : 577)
Query Neighborhood Hits	872	Target Neighborhood Hits	283	Shared Neighborhood Hits	123
SwissProt Accessions	Q61644	Gene names	Pacsin1, Pacsin
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

PACN1_HUMAN
NC score	0.147121 (rank : 199)	θ value	1.81305 (rank : 576)
Query Neighborhood Hits	872	Target Neighborhood Hits	320	Shared Neighborhood Hits	126
SwissProt Accessions	Q9BY11, Q9P2G8	Gene names	PACSIN1, KIAA1379
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

SAPS1_HUMAN
NC score	0.146711 (rank : 200)	θ value	5.27518 (rank : 736)
Query Neighborhood Hits	872	Target Neighborhood Hits	704	Shared Neighborhood Hits	299
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

SRRM1_MOUSE
NC score	0.146670 (rank : 201)	θ value	0.0252991 (rank : 243)
Query Neighborhood Hits	872	Target Neighborhood Hits	966	Shared Neighborhood Hits	240
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

NRX2B_HUMAN
NC score	0.145057 (rank : 202)	θ value	1.81305 (rank : 574)
Query Neighborhood Hits	872	Target Neighborhood Hits	481	Shared Neighborhood Hits	257
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

ATN1_HUMAN
NC score	0.144427 (rank : 203)	θ value	0.00665767 (rank : 178)
Query Neighborhood Hits	872	Target Neighborhood Hits	676	Shared Neighborhood Hits	194
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

BAT3_MOUSE
NC score	0.143810 (rank : 204)	θ value	0.0431538 (rank : 257)
Query Neighborhood Hits	872	Target Neighborhood Hits	518	Shared Neighborhood Hits	228
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

PSL1_HUMAN
NC score	0.143670 (rank : 205)	θ value	1.06291 (rank : 507)
Query Neighborhood Hits	872	Target Neighborhood Hits	650	Shared Neighborhood Hits	281
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

CASL_HUMAN
NC score	0.143547 (rank : 206)	θ value	6.88961 (rank : 759)
Query Neighborhood Hits	872	Target Neighborhood Hits	259	Shared Neighborhood Hits	139
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

DDEF2_MOUSE
NC score	0.143290 (rank : 207)	θ value	0.0193708 (rank : 225)
Query Neighborhood Hits	872	Target Neighborhood Hits	625	Shared Neighborhood Hits	172
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

PELP1_MOUSE
NC score	0.142595 (rank : 208)	θ value	0.47712 (rank : 418)
Query Neighborhood Hits	872	Target Neighborhood Hits	709	Shared Neighborhood Hits	248
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

WBP11_MOUSE
NC score	0.140778 (rank : 209)	θ value	0.000602161 (rank : 117)
Query Neighborhood Hits	872	Target Neighborhood Hits	362	Shared Neighborhood Hits	131
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

DDEF2_HUMAN
NC score	0.140744 (rank : 210)	θ value	4.03905 (rank : 678)
Query Neighborhood Hits	872	Target Neighborhood Hits	599	Shared Neighborhood Hits	169
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

SC24A_MOUSE
NC score	0.140675 (rank : 211)	θ value	0.0736092 (rank : 298)
Query Neighborhood Hits	872	Target Neighborhood Hits	394	Shared Neighborhood Hits	207
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

CRK_MOUSE
NC score	0.140578 (rank : 212)	θ value	θ > 10 (rank : 952)
Query Neighborhood Hits	872	Target Neighborhood Hits	314	Shared Neighborhood Hits	129
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

PACN3_MOUSE
NC score	0.140178 (rank : 213)	θ value	0.813845 (rank : 469)
Query Neighborhood Hits	872	Target Neighborhood Hits	380	Shared Neighborhood Hits	122
SwissProt Accessions	Q99JB8, Q9EQP9	Gene names	Pacsin3
Domain Architecture
Description	Protein kinase C and casein kinase II substrate protein 3.

BSN_HUMAN
NC score	0.140146 (rank : 214)	θ value	4.03905 (rank : 675)
Query Neighborhood Hits	872	Target Neighborhood Hits	1537	Shared Neighborhood Hits	362
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

ASPP1_HUMAN
NC score	0.139866 (rank : 215)	θ value	0.00228821 (rank : 142)
Query Neighborhood Hits	872	Target Neighborhood Hits	956	Shared Neighborhood Hits	198
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

WBP11_HUMAN
NC score	0.139302 (rank : 216)	θ value	0.00298849 (rank : 158)
Query Neighborhood Hits	872	Target Neighborhood Hits	354	Shared Neighborhood Hits	127
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

P85B_HUMAN
NC score	0.138192 (rank : 217)	θ value	0.365318 (rank : 394)
Query Neighborhood Hits	872	Target Neighborhood Hits	543	Shared Neighborhood Hits	92
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

WASF2_MOUSE
NC score	0.138171 (rank : 218)	θ value	0.00134147 (rank : 136)
Query Neighborhood Hits	872	Target Neighborhood Hits	315	Shared Neighborhood Hits	132
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

ARI1B_HUMAN
NC score	0.138073 (rank : 219)	θ value	0.000461057 (rank : 110)
Query Neighborhood Hits	872	Target Neighborhood Hits	567	Shared Neighborhood Hits	215
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

CRK_HUMAN
NC score	0.137688 (rank : 220)	θ value	θ > 10 (rank : 951)
Query Neighborhood Hits	872	Target Neighborhood Hits	308	Shared Neighborhood Hits	127
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

K1543_MOUSE
NC score	0.136924 (rank : 221)	θ value	0.0431538 (rank : 263)
Query Neighborhood Hits	872	Target Neighborhood Hits	497	Shared Neighborhood Hits	186
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

SPT5H_HUMAN
NC score	0.136758 (rank : 222)	θ value	2.36792 (rank : 621)
Query Neighborhood Hits	872	Target Neighborhood Hits	436	Shared Neighborhood Hits	201
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

SPT5H_MOUSE
NC score	0.136712 (rank : 223)	θ value	2.36792 (rank : 622)
Query Neighborhood Hits	872	Target Neighborhood Hits	437	Shared Neighborhood Hits	198
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

YLPM1_HUMAN
NC score	0.136369 (rank : 224)	θ value	0.00102713 (rank : 132)
Query Neighborhood Hits	872	Target Neighborhood Hits	670	Shared Neighborhood Hits	187
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

RERE_HUMAN
NC score	0.135572 (rank : 225)	θ value	1.43324e-05 (rank : 78)
Query Neighborhood Hits	872	Target Neighborhood Hits	779	Shared Neighborhood Hits	214
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

DDEF1_MOUSE
NC score	0.135456 (rank : 226)	θ value	θ > 10 (rank : 965)
Query Neighborhood Hits	872	Target Neighborhood Hits	592	Shared Neighborhood Hits	173
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

AHI1_HUMAN
NC score	0.135372 (rank : 227)	θ value	0.47712 (rank : 400)
Query Neighborhood Hits	872	Target Neighborhood Hits	537	Shared Neighborhood Hits	137
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

CBP_HUMAN
NC score	0.134992 (rank : 228)	θ value	0.365318 (rank : 389)
Query Neighborhood Hits	872	Target Neighborhood Hits	941	Shared Neighborhood Hits	294
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

PRR12_HUMAN
NC score	0.134745 (rank : 229)	θ value	0.00869519 (rank : 192)
Query Neighborhood Hits	872	Target Neighborhood Hits	460	Shared Neighborhood Hits	153
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

CASL_MOUSE
NC score	0.134634 (rank : 230)	θ value	θ > 10 (rank : 909)
Query Neighborhood Hits	872	Target Neighborhood Hits	225	Shared Neighborhood Hits	133
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

WASF2_HUMAN
NC score	0.134143 (rank : 231)	θ value	0.000270298 (rank : 103)
Query Neighborhood Hits	872	Target Neighborhood Hits	280	Shared Neighborhood Hits	118
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

GGN_MOUSE
NC score	0.133310 (rank : 232)	θ value	0.000158464 (rank : 93)
Query Neighborhood Hits	872	Target Neighborhood Hits	311	Shared Neighborhood Hits	112
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GGN_HUMAN
NC score	0.133003 (rank : 233)	θ value	0.0193708 (rank : 226)
Query Neighborhood Hits	872	Target Neighborhood Hits	269	Shared Neighborhood Hits	101
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

SPR1B_MOUSE
NC score	0.132687 (rank : 234)	θ value	θ > 10 (rank : 1114)
Query Neighborhood Hits	872	Target Neighborhood Hits	395	Shared Neighborhood Hits	192
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

AHI1_MOUSE
NC score	0.132385 (rank : 235)	θ value	0.365318 (rank : 388)
Query Neighborhood Hits	872	Target Neighborhood Hits	496	Shared Neighborhood Hits	137
SwissProt Accessions	Q8K3E5, Q7TNV2, Q9CVY1	Gene names	Ahi1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein) (AHI-1).

TAB3_MOUSE
NC score	0.132210 (rank : 236)	θ value	2.21117e-06 (rank : 68)
Query Neighborhood Hits	872	Target Neighborhood Hits	273	Shared Neighborhood Hits	108
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

PRB3_HUMAN
NC score	0.131471 (rank : 237)	θ value	0.00228821 (rank : 146)
Query Neighborhood Hits	872	Target Neighborhood Hits	318	Shared Neighborhood Hits	117
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

SNPC4_HUMAN
NC score	0.131017 (rank : 238)	θ value	θ > 10 (rank : 1103)
Query Neighborhood Hits	872	Target Neighborhood Hits	589	Shared Neighborhood Hits	246
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

WASF4_HUMAN
NC score	0.130880 (rank : 239)	θ value	0.00175202 (rank : 141)
Query Neighborhood Hits	872	Target Neighborhood Hits	282	Shared Neighborhood Hits	121
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

FMNL_HUMAN
NC score	0.130187 (rank : 240)	θ value	0.00390308 (rank : 161)
Query Neighborhood Hits	872	Target Neighborhood Hits	529	Shared Neighborhood Hits	149
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

NFH_MOUSE
NC score	0.129848 (rank : 241)	θ value	0.00035302 (rank : 108)
Query Neighborhood Hits	872	Target Neighborhood Hits	2247	Shared Neighborhood Hits	413
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

ZIM10_MOUSE
NC score	0.128779 (rank : 242)	θ value	4.03905 (rank : 705)
Query Neighborhood Hits	872	Target Neighborhood Hits	430	Shared Neighborhood Hits	232
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

FA47B_HUMAN
NC score	0.128575 (rank : 243)	θ value	θ > 10 (rank : 985)
Query Neighborhood Hits	872	Target Neighborhood Hits	431	Shared Neighborhood Hits	181
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

PACN3_HUMAN
NC score	0.128112 (rank : 244)	θ value	θ > 10 (rank : 1063)
Query Neighborhood Hits	872	Target Neighborhood Hits	385	Shared Neighborhood Hits	122
SwissProt Accessions	Q9UKS6, Q9H331, Q9NWV9	Gene names	PACSIN3
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) (Endophilin I).

SMR3A_HUMAN
NC score	0.127890 (rank : 245)	θ value	0.00390308 (rank : 166)
Query Neighborhood Hits	872	Target Neighborhood Hits	93	Shared Neighborhood Hits	37
SwissProt Accessions	Q99954	Gene names	SMR3A, PBI, PROL5
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog A precursor (Proline-rich protein 5) (Proline-rich protein PBI).

MKL1_MOUSE
NC score	0.127104 (rank : 246)	θ value	1.81305 (rank : 571)
Query Neighborhood Hits	872	Target Neighborhood Hits	667	Shared Neighborhood Hits	284
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

DBNL_HUMAN
NC score	0.126606 (rank : 247)	θ value	θ > 10 (rank : 962)
Query Neighborhood Hits	872	Target Neighborhood Hits	244	Shared Neighborhood Hits	108
SwissProt Accessions	Q9UJU6, P84070, Q6IAI8, Q96F30, Q96K74, Q9HBN8, Q9NR72	Gene names	DBNL, CMAP, SH3P7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein).

RERE_MOUSE
NC score	0.126389 (rank : 248)	θ value	0.0563607 (rank : 283)
Query Neighborhood Hits	872	Target Neighborhood Hits	785	Shared Neighborhood Hits	211
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

RAPH1_HUMAN
NC score	0.126214 (rank : 249)	θ value	0.00509761 (rank : 173)
Query Neighborhood Hits	872	Target Neighborhood Hits	593	Shared Neighborhood Hits	179
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

YLPM1_MOUSE
NC score	0.125903 (rank : 250)	θ value	0.0193708 (rank : 234)
Query Neighborhood Hits	872	Target Neighborhood Hits	505	Shared Neighborhood Hits	152
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

CO5A2_HUMAN
NC score	0.125080 (rank : 251)	θ value	θ > 10 (rank : 937)
Query Neighborhood Hits	872	Target Neighborhood Hits	760	Shared Neighborhood Hits	247
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

MLL2_HUMAN
NC score	0.125037 (rank : 252)	θ value	0.00869519 (rank : 188)
Query Neighborhood Hits	872	Target Neighborhood Hits	1788	Shared Neighborhood Hits	360
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

DBNL_MOUSE
NC score	0.123694 (rank : 253)	θ value	θ > 10 (rank : 963)
Query Neighborhood Hits	872	Target Neighborhood Hits	306	Shared Neighborhood Hits	113
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

ALEX_HUMAN
NC score	0.123597 (rank : 254)	θ value	0.0736092 (rank : 289)
Query Neighborhood Hits	872	Target Neighborhood Hits	361	Shared Neighborhood Hits	134
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

NPHP1_MOUSE
NC score	0.123094 (rank : 255)	θ value	θ > 10 (rank : 1056)
Query Neighborhood Hits	872	Target Neighborhood Hits	267	Shared Neighborhood Hits	114
SwissProt Accessions	Q9QY53, Q9D7G8, Q9QZP0, Q9WUZ2	Gene names	Nphp1, Nph1
Domain Architecture
Description	Nephrocystin-1.

ENAH_MOUSE
NC score	0.122966 (rank : 256)	θ value	6.43352e-06 (rank : 73)
Query Neighborhood Hits	872	Target Neighborhood Hits	919	Shared Neighborhood Hits	198
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

BAG3_MOUSE
NC score	0.122131 (rank : 257)	θ value	4.03905 (rank : 673)
Query Neighborhood Hits	872	Target Neighborhood Hits	513	Shared Neighborhood Hits	212
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

MYO1F_HUMAN
NC score	0.121543 (rank : 258)	θ value	0.00509761 (rank : 172)
Query Neighborhood Hits	872	Target Neighborhood Hits	275	Shared Neighborhood Hits	133
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

SON_MOUSE
NC score	0.121113 (rank : 259)	θ value	θ > 10 (rank : 1107)
Query Neighborhood Hits	872	Target Neighborhood Hits	957	Shared Neighborhood Hits	284
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

OGFR_MOUSE
NC score	0.120570 (rank : 260)	θ value	5.27518 (rank : 728)
Query Neighborhood Hits	872	Target Neighborhood Hits	584	Shared Neighborhood Hits	168
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

EP300_HUMAN
NC score	0.120039 (rank : 261)	θ value	0.62314 (rank : 432)
Query Neighborhood Hits	872	Target Neighborhood Hits	821	Shared Neighborhood Hits	254
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

MYO1E_HUMAN
NC score	0.119964 (rank : 262)	θ value	0.00228821 (rank : 144)
Query Neighborhood Hits	872	Target Neighborhood Hits	293	Shared Neighborhood Hits	137
SwissProt Accessions	Q12965, Q14778	Gene names	MYO1E, MYO1C
Domain Architecture
Description	Myosin Ie (Myosin Ic).

CRSP2_HUMAN
NC score	0.119842 (rank : 263)	θ value	θ > 10 (rank : 953)
Query Neighborhood Hits	872	Target Neighborhood Hits	380	Shared Neighborhood Hits	184
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

MYO1F_MOUSE
NC score	0.119832 (rank : 264)	θ value	0.0113563 (rank : 203)
Query Neighborhood Hits	872	Target Neighborhood Hits	262	Shared Neighborhood Hits	128
SwissProt Accessions	P70248	Gene names	Myo1f
Domain Architecture
Description	Myosin If.

SRRM2_MOUSE
NC score	0.119626 (rank : 265)	θ value	2.36792 (rank : 624)
Query Neighborhood Hits	872	Target Neighborhood Hits	1470	Shared Neighborhood Hits	283
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

GRIN1_HUMAN
NC score	0.118935 (rank : 266)	θ value	6.88961 (rank : 775)
Query Neighborhood Hits	872	Target Neighborhood Hits	681	Shared Neighborhood Hits	214
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

RSMN_HUMAN
NC score	0.118791 (rank : 267)	θ value	0.00020696 (rank : 99)
Query Neighborhood Hits	872	Target Neighborhood Hits	110	Shared Neighborhood Hits	45
SwissProt Accessions	P63162, P14648, P17135	Gene names	SNRPN, HCERN3, SMN
Domain Architecture	No domain graphic available
Description	Small nuclear ribonucleoprotein-associated protein N (snRNP-N) (Sm protein N) (Sm-N) (SmN) (Sm-D) (Tissue-specific-splicing protein).

RSMN_MOUSE
NC score	0.118791 (rank : 268)	θ value	0.00020696 (rank : 100)
Query Neighborhood Hits	872	Target Neighborhood Hits	110	Shared Neighborhood Hits	45
SwissProt Accessions	P63163, P14648, P17135	Gene names	Snrpn, Smn
Domain Architecture	No domain graphic available
Description	Small nuclear ribonucleoprotein-associated protein N (snRNP-N) (Sm protein N) (Sm-N) (SmN) (Sm-D) (Tissue-specific-splicing protein).

WASF1_MOUSE
NC score	0.118780 (rank : 269)	θ value	0.0736092 (rank : 301)
Query Neighborhood Hits	872	Target Neighborhood Hits	261	Shared Neighborhood Hits	106
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

RSMB_HUMAN
NC score	0.118452 (rank : 270)	θ value	0.00102713 (rank : 127)
Query Neighborhood Hits	872	Target Neighborhood Hits	117	Shared Neighborhood Hits	51
SwissProt Accessions	P14678, Q15490, Q9UIS5	Gene names	SNRPB, COD, SNRPB1
Domain Architecture
Description	Small nuclear ribonucleoprotein-associated proteins B and B' (snRNP-B) (Sm protein B/B') (Sm-B/Sm-B') (SmB/SmB').

ATX2L_MOUSE
NC score	0.118231 (rank : 271)	θ value	0.0113563 (rank : 196)
Query Neighborhood Hits	872	Target Neighborhood Hits	401	Shared Neighborhood Hits	153
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

RUSC1_HUMAN
NC score	0.117889 (rank : 272)	θ value	1.81305 (rank : 582)
Query Neighborhood Hits	872	Target Neighborhood Hits	226	Shared Neighborhood Hits	115
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

NOXO1_MOUSE
NC score	0.117604 (rank : 273)	θ value	θ > 10 (rank : 1054)
Query Neighborhood Hits	872	Target Neighborhood Hits	114	Shared Neighborhood Hits	82
SwissProt Accessions	Q8VCM2, Q3TZA4, Q8BH41, Q9D747	Gene names	Noxo1, Snx28
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Sorting nexin-28).

NUMBL_HUMAN
NC score	0.117290 (rank : 274)	θ value	θ > 10 (rank : 1058)
Query Neighborhood Hits	872	Target Neighborhood Hits	394	Shared Neighborhood Hits	213
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

MTSS1_MOUSE
NC score	0.117260 (rank : 275)	θ value	θ > 10 (rank : 1044)
Query Neighborhood Hits	872	Target Neighborhood Hits	592	Shared Neighborhood Hits	243
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

FMN2_HUMAN
NC score	0.116881 (rank : 276)	θ value	0.00665767 (rank : 180)
Query Neighborhood Hits	872	Target Neighborhood Hits	484	Shared Neighborhood Hits	139
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

WASF1_HUMAN
NC score	0.116803 (rank : 277)	θ value	0.0961366 (rank : 316)
Query Neighborhood Hits	872	Target Neighborhood Hits	260	Shared Neighborhood Hits	108
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

BAT3_HUMAN
NC score	0.116652 (rank : 278)	θ value	θ > 10 (rank : 903)
Query Neighborhood Hits	872	Target Neighborhood Hits	490	Shared Neighborhood Hits	222
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

TPO_MOUSE
NC score	0.116316 (rank : 279)	θ value	θ > 10 (rank : 1133)
Query Neighborhood Hits	872	Target Neighborhood Hits	258	Shared Neighborhood Hits	152
SwissProt Accessions	P40226	Gene names	Thpo
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

MUCDL_HUMAN
NC score	0.116107 (rank : 280)	θ value	θ > 10 (rank : 1046)
Query Neighborhood Hits	872	Target Neighborhood Hits	777	Shared Neighborhood Hits	280
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

SHAN1_HUMAN
NC score	0.116086 (rank : 281)	θ value	0.00390308 (rank : 165)
Query Neighborhood Hits	872	Target Neighborhood Hits	1041	Shared Neighborhood Hits	269
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

ASPP2_HUMAN
NC score	0.115399 (rank : 282)	θ value	1.81305 (rank : 555)
Query Neighborhood Hits	872	Target Neighborhood Hits	1156	Shared Neighborhood Hits	221
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

MUC7_HUMAN
NC score	0.115032 (rank : 283)	θ value	0.163984 (rank : 347)
Query Neighborhood Hits	872	Target Neighborhood Hits	538	Shared Neighborhood Hits	144
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

NOXO1_HUMAN
NC score	0.115022 (rank : 284)	θ value	0.21417 (rank : 367)
Query Neighborhood Hits	872	Target Neighborhood Hits	100	Shared Neighborhood Hits	66
SwissProt Accessions	Q8NFA2, Q86YM1, Q8NFA3, Q96B73	Gene names	NOXO1, P41NOX
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Nox-organizing protein 1) (NADPH oxidase regulatory protein).

RUSC1_MOUSE
NC score	0.114797 (rank : 285)	θ value	1.38821 (rank : 546)
Query Neighborhood Hits	872	Target Neighborhood Hits	206	Shared Neighborhood Hits	103
SwissProt Accessions	Q8BG26, Q6PHT9	Gene names	Rusc1
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1.

WASF3_HUMAN
NC score	0.114671 (rank : 286)	θ value	0.0193708 (rank : 233)
Query Neighborhood Hits	872	Target Neighborhood Hits	204	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UPY6, O94974	Gene names	WASF3, KIAA0900, SCAR3, WAVE3
Domain Architecture
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3) (Verprolin homology domain-containing protein 3).

NGEF_MOUSE
NC score	0.114614 (rank : 287)	θ value	0.0431538 (rank : 264)
Query Neighborhood Hits	872	Target Neighborhood Hits	228	Shared Neighborhood Hits	93
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

CO039_MOUSE
NC score	0.114124 (rank : 288)	θ value	θ > 10 (rank : 933)
Query Neighborhood Hits	872	Target Neighborhood Hits	445	Shared Neighborhood Hits	200
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

SELPL_MOUSE
NC score	0.113075 (rank : 289)	θ value	θ > 10 (rank : 1090)
Query Neighborhood Hits	872	Target Neighborhood Hits	588	Shared Neighborhood Hits	182
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

CSF1_HUMAN
NC score	0.112964 (rank : 290)	θ value	θ > 10 (rank : 956)
Query Neighborhood Hits	872	Target Neighborhood Hits	258	Shared Neighborhood Hits	112
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

ATX2L_HUMAN
NC score	0.112765 (rank : 291)	θ value	0.21417 (rank : 359)
Query Neighborhood Hits	872	Target Neighborhood Hits	443	Shared Neighborhood Hits	149
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

NGEF_HUMAN
NC score	0.112621 (rank : 292)	θ value	0.0252991 (rank : 240)
Query Neighborhood Hits	872	Target Neighborhood Hits	166	Shared Neighborhood Hits	76
SwissProt Accessions	Q8N5V2, Q53QQ4, Q53ST7, Q6GMQ5, Q9NQD6	Gene names	NGEF
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

PRB4S_HUMAN
NC score	0.112377 (rank : 293)	θ value	5.27518 (rank : 733)
Query Neighborhood Hits	872	Target Neighborhood Hits	330	Shared Neighborhood Hits	120
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

ATX2_MOUSE
NC score	0.112307 (rank : 294)	θ value	0.125558 (rank : 319)
Query Neighborhood Hits	872	Target Neighborhood Hits	445	Shared Neighborhood Hits	161
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

LASP1_HUMAN
NC score	0.112271 (rank : 295)	θ value	θ > 10 (rank : 1025)
Query Neighborhood Hits	872	Target Neighborhood Hits	293	Shared Neighborhood Hits	120
SwissProt Accessions	Q14847, Q96ED2, Q96IG0	Gene names	LASP1, MLN50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

SC24D_HUMAN
NC score	0.111543 (rank : 296)	θ value	2.88788e-06 (rank : 71)
Query Neighborhood Hits	872	Target Neighborhood Hits	173	Shared Neighborhood Hits	67
SwissProt Accessions	O94855	Gene names	SEC24D, KIAA0755
Domain Architecture
Description	Protein transport protein Sec24D (SEC24-related protein D).

PLCG1_MOUSE
NC score	0.111123 (rank : 297)	θ value	θ > 10 (rank : 1075)
Query Neighborhood Hits	872	Target Neighborhood Hits	314	Shared Neighborhood Hits	122
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

T22D4_HUMAN
NC score	0.111074 (rank : 298)	θ value	θ > 10 (rank : 1123)
Query Neighborhood Hits	872	Target Neighborhood Hits	403	Shared Neighborhood Hits	186
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

LASP1_MOUSE
NC score	0.110986 (rank : 299)	θ value	θ > 10 (rank : 1026)
Query Neighborhood Hits	872	Target Neighborhood Hits	297	Shared Neighborhood Hits	119
SwissProt Accessions	Q61792, Q62416	Gene names	Lasp1, Mln50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

WASL_MOUSE
NC score	0.110777 (rank : 300)	θ value	0.00102713 (rank : 131)
Query Neighborhood Hits	872	Target Neighborhood Hits	339	Shared Neighborhood Hits	126
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

FMN2_MOUSE
NC score	0.110285 (rank : 301)	θ value	0.0736092 (rank : 294)
Query Neighborhood Hits	872	Target Neighborhood Hits	349	Shared Neighborhood Hits	129
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

FA47A_HUMAN
NC score	0.110054 (rank : 302)	θ value	θ > 10 (rank : 984)
Query Neighborhood Hits	872	Target Neighborhood Hits	451	Shared Neighborhood Hits	169
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

DOT1L_HUMAN
NC score	0.109284 (rank : 303)	θ value	0.0252991 (rank : 238)
Query Neighborhood Hits	872	Target Neighborhood Hits	660	Shared Neighborhood Hits	158
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

SHAN2_MOUSE
NC score	0.109209 (rank : 304)	θ value	0.163984 (rank : 354)
Query Neighborhood Hits	872	Target Neighborhood Hits	446	Shared Neighborhood Hits	135
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

NPHP1_HUMAN
NC score	0.109201 (rank : 305)	θ value	θ > 10 (rank : 1055)
Query Neighborhood Hits	872	Target Neighborhood Hits	288	Shared Neighborhood Hits	105
SwissProt Accessions	O15259, O14837	Gene names	NPHP1, NPH1
Domain Architecture
Description	Nephrocystin-1 (Juvenile nephronophthisis 1 protein).

CK024_HUMAN
NC score	0.108434 (rank : 306)	θ value	θ > 10 (rank : 928)
Query Neighborhood Hits	872	Target Neighborhood Hits	408	Shared Neighborhood Hits	156
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

SRRM1_HUMAN
NC score	0.108431 (rank : 307)	θ value	0.0148317 (rank : 218)
Query Neighborhood Hits	872	Target Neighborhood Hits	690	Shared Neighborhood Hits	142
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

WASF3_MOUSE
NC score	0.108341 (rank : 308)	θ value	0.279714 (rank : 386)
Query Neighborhood Hits	872	Target Neighborhood Hits	188	Shared Neighborhood Hits	71
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

MINT_MOUSE
NC score	0.108186 (rank : 309)	θ value	2.36792 (rank : 605)
Query Neighborhood Hits	872	Target Neighborhood Hits	1514	Shared Neighborhood Hits	310
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

EPN3_MOUSE
NC score	0.108142 (rank : 310)	θ value	0.365318 (rank : 390)
Query Neighborhood Hits	872	Target Neighborhood Hits	312	Shared Neighborhood Hits	141
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

GNAS1_MOUSE
NC score	0.108024 (rank : 311)	θ value	0.21417 (rank : 365)
Query Neighborhood Hits	872	Target Neighborhood Hits	651	Shared Neighborhood Hits	272
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

PLCG1_HUMAN
NC score	0.106926 (rank : 312)	θ value	θ > 10 (rank : 1074)
Query Neighborhood Hits	872	Target Neighborhood Hits	293	Shared Neighborhood Hits	116
SwissProt Accessions	P19174, Q2V575	Gene names	PLCG1, PLC1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

SF01_HUMAN
NC score	0.106872 (rank : 313)	θ value	0.00298849 (rank : 155)
Query Neighborhood Hits	872	Target Neighborhood Hits	287	Shared Neighborhood Hits	106
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

P85B_MOUSE
NC score	0.106843 (rank : 314)	θ value	1.81305 (rank : 575)
Query Neighborhood Hits	872	Target Neighborhood Hits	519	Shared Neighborhood Hits	72
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

PLCG2_HUMAN
NC score	0.106694 (rank : 315)	θ value	θ > 10 (rank : 1076)
Query Neighborhood Hits	872	Target Neighborhood Hits	280	Shared Neighborhood Hits	113
SwissProt Accessions	P16885, Q969T5	Gene names	PLCG2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV).

FMNL_MOUSE
NC score	0.106368 (rank : 316)	θ value	0.00102713 (rank : 126)
Query Neighborhood Hits	872	Target Neighborhood Hits	428	Shared Neighborhood Hits	108
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

SMRC2_MOUSE
NC score	0.105881 (rank : 317)	θ value	4.1701e-05 (rank : 84)
Query Neighborhood Hits	872	Target Neighborhood Hits	487	Shared Neighborhood Hits	101
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

PYGO2_HUMAN
NC score	0.105609 (rank : 318)	θ value	0.00390308 (rank : 164)
Query Neighborhood Hits	872	Target Neighborhood Hits	189	Shared Neighborhood Hits	98
SwissProt Accessions	Q9BRQ0, Q8WYZ4, Q96CY2	Gene names	PYGO2
Domain Architecture
Description	Pygopus homolog 2.

RSMB_MOUSE
NC score	0.105385 (rank : 319)	θ value	0.0193708 (rank : 231)
Query Neighborhood Hits	872	Target Neighborhood Hits	93	Shared Neighborhood Hits	40
SwissProt Accessions	P27048, Q3UJT1	Gene names	Snrpb
Domain Architecture
Description	Small nuclear ribonucleoprotein-associated protein B (snRNP-B) (Sm protein B) (Sm-B) (SmB).

WASL_HUMAN
NC score	0.105298 (rank : 320)	θ value	0.00869519 (rank : 195)
Query Neighborhood Hits	872	Target Neighborhood Hits	312	Shared Neighborhood Hits	118
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

CIC_MOUSE
NC score	0.105250 (rank : 321)	θ value	0.0113563 (rank : 199)
Query Neighborhood Hits	872	Target Neighborhood Hits	742	Shared Neighborhood Hits	236
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

SYN1_HUMAN
NC score	0.105033 (rank : 322)	θ value	0.00869519 (rank : 194)
Query Neighborhood Hits	872	Target Neighborhood Hits	419	Shared Neighborhood Hits	147
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

MYO15_HUMAN
NC score	0.104593 (rank : 323)	θ value	0.0148317 (rank : 211)
Query Neighborhood Hits	872	Target Neighborhood Hits	671	Shared Neighborhood Hits	286
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

SYNJ1_MOUSE
NC score	0.104261 (rank : 324)	θ value	0.125558 (rank : 328)
Query Neighborhood Hits	872	Target Neighborhood Hits	516	Shared Neighborhood Hits	182
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

RUSC2_MOUSE
NC score	0.103756 (rank : 325)	θ value	3.0926 (rank : 661)
Query Neighborhood Hits	872	Target Neighborhood Hits	305	Shared Neighborhood Hits	142
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

SMRC2_HUMAN
NC score	0.103089 (rank : 326)	θ value	0.000461057 (rank : 112)
Query Neighborhood Hits	872	Target Neighborhood Hits	499	Shared Neighborhood Hits	103
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

K1802_HUMAN
NC score	0.102995 (rank : 327)	θ value	0.813845 (rank : 461)
Query Neighborhood Hits	872	Target Neighborhood Hits	1378	Shared Neighborhood Hits	293
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

IL3B2_MOUSE
NC score	0.102770 (rank : 328)	θ value	0.62314 (rank : 434)
Query Neighborhood Hits	872	Target Neighborhood Hits	372	Shared Neighborhood Hits	191
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

ZN207_HUMAN
NC score	0.102338 (rank : 329)	θ value	0.0252991 (rank : 247)
Query Neighborhood Hits	872	Target Neighborhood Hits	326	Shared Neighborhood Hits	75
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

K1543_HUMAN
NC score	0.101815 (rank : 330)	θ value	θ > 10 (rank : 1023)
Query Neighborhood Hits	872	Target Neighborhood Hits	435	Shared Neighborhood Hits	172
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

NEBL_HUMAN
NC score	0.101582 (rank : 331)	θ value	θ > 10 (rank : 1050)
Query Neighborhood Hits	872	Target Neighborhood Hits	457	Shared Neighborhood Hits	121
SwissProt Accessions	O76041, Q9UIC4	Gene names	NEBL
Domain Architecture
Description	Nebulette (Actin-binding Z-disk protein).

TULP4_HUMAN
NC score	0.101350 (rank : 332)	θ value	θ > 10 (rank : 1136)
Query Neighborhood Hits	872	Target Neighborhood Hits	426	Shared Neighborhood Hits	171
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

SFPQ_MOUSE
NC score	0.100107 (rank : 333)	θ value	0.0148317 (rank : 216)
Query Neighborhood Hits	872	Target Neighborhood Hits	958	Shared Neighborhood Hits	197
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

CJ108_HUMAN
NC score	0.099417 (rank : 334)	θ value	θ > 10 (rank : 927)
Query Neighborhood Hits	872	Target Neighborhood Hits	165	Shared Neighborhood Hits	98
SwissProt Accessions	Q8N8Z3	Gene names	C10orf108
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C10orf108.

CO9A1_MOUSE
NC score	0.099027 (rank : 335)	θ value	0.813845 (rank : 454)
Query Neighborhood Hits	872	Target Neighborhood Hits	477	Shared Neighborhood Hits	174
SwissProt Accessions	Q05722, Q61269, Q61270, Q61433, Q61940	Gene names	Col9a1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

MILK1_MOUSE
NC score	0.098758 (rank : 336)	θ value	0.0961366 (rank : 310)
Query Neighborhood Hits	872	Target Neighborhood Hits	788	Shared Neighborhood Hits	268
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

CABIN_HUMAN
NC score	0.098636 (rank : 337)	θ value	θ > 10 (rank : 907)
Query Neighborhood Hits	872	Target Neighborhood Hits	490	Shared Neighborhood Hits	187
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

R3HD2_MOUSE
NC score	0.098484 (rank : 338)	θ value	θ > 10 (rank : 1081)
Query Neighborhood Hits	872	Target Neighborhood Hits	397	Shared Neighborhood Hits	149
SwissProt Accessions	Q80TM6, Q80YB1, Q8BLS5, Q9CW50	Gene names	R3hdm2, Kiaa1002
Domain Architecture
Description	R3H domain-containing protein 2.

CO4A4_HUMAN
NC score	0.098348 (rank : 339)	θ value	0.813845 (rank : 453)
Query Neighborhood Hits	872	Target Neighborhood Hits	440	Shared Neighborhood Hits	166
SwissProt Accessions	P53420	Gene names	COL4A4
Domain Architecture
Description	Collagen alpha-4(IV) chain precursor.

K0310_HUMAN
NC score	0.098129 (rank : 340)	θ value	1.81305 (rank : 569)
Query Neighborhood Hits	872	Target Neighborhood Hits	420	Shared Neighborhood Hits	166
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

SFR15_HUMAN
NC score	0.098123 (rank : 341)	θ value	0.0431538 (rank : 267)
Query Neighborhood Hits	872	Target Neighborhood Hits	368	Shared Neighborhood Hits	106
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

SPR1A_MOUSE
NC score	0.097911 (rank : 342)	θ value	θ > 10 (rank : 1113)
Query Neighborhood Hits	872	Target Neighborhood Hits	343	Shared Neighborhood Hits	162
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

NRX2A_HUMAN
NC score	0.097856 (rank : 343)	θ value	1.81305 (rank : 573)
Query Neighborhood Hits	872	Target Neighborhood Hits	614	Shared Neighborhood Hits	269
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

SYN1_MOUSE
NC score	0.097792 (rank : 344)	θ value	0.000461057 (rank : 113)
Query Neighborhood Hits	872	Target Neighborhood Hits	363	Shared Neighborhood Hits	125
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

IL3RB_MOUSE
NC score	0.097583 (rank : 345)	θ value	0.813845 (rank : 460)
Query Neighborhood Hits	872	Target Neighborhood Hits	355	Shared Neighborhood Hits	179
SwissProt Accessions	P26955	Gene names	Csf2rb, Aic2b, Csf2rb1, Il3rb1
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen).

SF01_MOUSE
NC score	0.097295 (rank : 346)	θ value	0.00509761 (rank : 174)
Query Neighborhood Hits	872	Target Neighborhood Hits	240	Shared Neighborhood Hits	85
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

SRRM2_HUMAN
NC score	0.097245 (rank : 347)	θ value	8.99809 (rank : 862)
Query Neighborhood Hits	872	Target Neighborhood Hits	1296	Shared Neighborhood Hits	229
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

S23IP_MOUSE
NC score	0.097102 (rank : 348)	θ value	1.06291 (rank : 509)
Query Neighborhood Hits	872	Target Neighborhood Hits	363	Shared Neighborhood Hits	162
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

SFPQ_HUMAN
NC score	0.097028 (rank : 349)	θ value	0.0148317 (rank : 215)
Query Neighborhood Hits	872	Target Neighborhood Hits	986	Shared Neighborhood Hits	205
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

CO002_HUMAN
NC score	0.097011 (rank : 350)	θ value	θ > 10 (rank : 931)
Query Neighborhood Hits	872	Target Neighborhood Hits	387	Shared Neighborhood Hits	149
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

CO1A1_HUMAN
NC score	0.096791 (rank : 351)	θ value	1.38821 (rank : 527)
Query Neighborhood Hits	872	Target Neighborhood Hits	475	Shared Neighborhood Hits	157
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CO3A1_MOUSE
NC score	0.096612 (rank : 352)	θ value	0.62314 (rank : 428)
Query Neighborhood Hits	872	Target Neighborhood Hits	466	Shared Neighborhood Hits	151
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CO1A2_MOUSE
NC score	0.096393 (rank : 353)	θ value	0.0563607 (rank : 275)
Query Neighborhood Hits	872	Target Neighborhood Hits	388	Shared Neighborhood Hits	136
SwissProt Accessions	Q01149, Q8CGA5	Gene names	Col1a2, Cola2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

CO1A1_MOUSE
NC score	0.096247 (rank : 354)	θ value	0.0961366 (rank : 305)
Query Neighborhood Hits	872	Target Neighborhood Hits	457	Shared Neighborhood Hits	148
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

T22D2_HUMAN
NC score	0.095975 (rank : 355)	θ value	0.0148317 (rank : 219)
Query Neighborhood Hits	872	Target Neighborhood Hits	250	Shared Neighborhood Hits	93
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

CSKI1_MOUSE
NC score	0.095837 (rank : 356)	θ value	θ > 10 (rank : 957)
Query Neighborhood Hits	872	Target Neighborhood Hits	1031	Shared Neighborhood Hits	327
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

TIAM1_HUMAN
NC score	0.095593 (rank : 357)	θ value	0.813845 (rank : 480)
Query Neighborhood Hits	872	Target Neighborhood Hits	225	Shared Neighborhood Hits	48
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

GPS2_HUMAN
NC score	0.095583 (rank : 358)	θ value	θ > 10 (rank : 1008)
Query Neighborhood Hits	872	Target Neighborhood Hits	459	Shared Neighborhood Hits	127
SwissProt Accessions	Q13227	Gene names	GPS2
Domain Architecture	No domain graphic available
Description	G protein pathway suppressor 2 (Protein GPS2).

PREX1_HUMAN
NC score	0.095184 (rank : 359)	θ value	θ > 10 (rank : 1077)
Query Neighborhood Hits	872	Target Neighborhood Hits	177	Shared Neighborhood Hits	39
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

COBA1_HUMAN
NC score	0.094236 (rank : 360)	θ value	1.06291 (rank : 489)
Query Neighborhood Hits	872	Target Neighborhood Hits	491	Shared Neighborhood Hits	157
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

SRBP1_MOUSE
NC score	0.094083 (rank : 361)	θ value	0.0961366 (rank : 315)
Query Neighborhood Hits	872	Target Neighborhood Hits	384	Shared Neighborhood Hits	161
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

ARHGG_MOUSE
NC score	0.094033 (rank : 362)	θ value	3.0926 (rank : 630)
Query Neighborhood Hits	872	Target Neighborhood Hits	152	Shared Neighborhood Hits	62
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

DMRTD_HUMAN
NC score	0.094018 (rank : 363)	θ value	5.27518 (rank : 714)
Query Neighborhood Hits	872	Target Neighborhood Hits	216	Shared Neighborhood Hits	125
SwissProt Accessions	Q8IXT2, Q8N6Q2, Q96M39, Q96SD4	Gene names	DMRTC2
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2.

SYNJ1_HUMAN
NC score	0.093962 (rank : 364)	θ value	0.21417 (rank : 368)
Query Neighborhood Hits	872	Target Neighborhood Hits	498	Shared Neighborhood Hits	170
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

CO4A3_HUMAN
NC score	0.093904 (rank : 365)	θ value	2.36792 (rank : 589)
Query Neighborhood Hits	872	Target Neighborhood Hits	421	Shared Neighborhood Hits	151
SwissProt Accessions	Q01955, Q9BQT2	Gene names	COL4A3
Domain Architecture
Description	Collagen alpha-3(IV) chain precursor (Goodpasture antigen).

ATX2_HUMAN
NC score	0.093880 (rank : 366)	θ value	0.125558 (rank : 318)
Query Neighborhood Hits	872	Target Neighborhood Hits	375	Shared Neighborhood Hits	114
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

CO3A1_HUMAN
NC score	0.093822 (rank : 367)	θ value	0.62314 (rank : 427)
Query Neighborhood Hits	872	Target Neighborhood Hits	452	Shared Neighborhood Hits	150
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CO4A2_MOUSE
NC score	0.093597 (rank : 368)	θ value	θ > 10 (rank : 935)
Query Neighborhood Hits	872	Target Neighborhood Hits	492	Shared Neighborhood Hits	178
SwissProt Accessions	P08122, Q61375	Gene names	Col4a2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

FMN1A_MOUSE
NC score	0.093540 (rank : 369)	θ value	0.47712 (rank : 409)
Query Neighborhood Hits	872	Target Neighborhood Hits	423	Shared Neighborhood Hits	128
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

FMN1B_MOUSE
NC score	0.093343 (rank : 370)	θ value	0.47712 (rank : 410)
Query Neighborhood Hits	872	Target Neighborhood Hits	447	Shared Neighborhood Hits	124
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

CO2A1_HUMAN
NC score	0.093112 (rank : 371)	θ value	1.38821 (rank : 528)
Query Neighborhood Hits	872	Target Neighborhood Hits	486	Shared Neighborhood Hits	174
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

MEF2B_MOUSE
NC score	0.093110 (rank : 372)	θ value	0.813845 (rank : 464)
Query Neighborhood Hits	872	Target Neighborhood Hits	218	Shared Neighborhood Hits	125
SwissProt Accessions	O55087, O55088, O55089, O55090, O55231, Q61843	Gene names	Mef2b
Domain Architecture
Description	Myocyte-specific enhancer factor 2B.

PEX13_HUMAN
NC score	0.093072 (rank : 373)	θ value	θ > 10 (rank : 1068)
Query Neighborhood Hits	872	Target Neighborhood Hits	128	Shared Neighborhood Hits	85
SwissProt Accessions	Q92968	Gene names	PEX13
Domain Architecture
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

PEX13_MOUSE
NC score	0.092993 (rank : 374)	θ value	θ > 10 (rank : 1069)
Query Neighborhood Hits	872	Target Neighborhood Hits	126	Shared Neighborhood Hits	84
SwissProt Accessions	Q9D0K1, Q3U5T1, Q8CCJ5, Q8CCW5, Q99MM2, Q9EPK1	Gene names	Pex13
Domain Architecture	No domain graphic available
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

COBA1_MOUSE
NC score	0.092873 (rank : 375)	θ value	5.27518 (rank : 710)
Query Neighborhood Hits	872	Target Neighborhood Hits	487	Shared Neighborhood Hits	155
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

ARHG5_HUMAN
NC score	0.092801 (rank : 376)	θ value	θ > 10 (rank : 886)
Query Neighborhood Hits	872	Target Neighborhood Hits	172	Shared Neighborhood Hits	80
SwissProt Accessions	Q12774	Gene names	ARHGEF5, TIM
Domain Architecture
Description	Rho guanine nucleotide exchange factor 5 (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (p60 TIM) (Transforming immortalized mammary oncogene).

CS016_HUMAN
NC score	0.092655 (rank : 377)	θ value	1.06291 (rank : 491)
Query Neighborhood Hits	872	Target Neighborhood Hits	310	Shared Neighborhood Hits	105
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

EPN1_MOUSE
NC score	0.092443 (rank : 378)	θ value	0.000602161 (rank : 115)
Query Neighborhood Hits	872	Target Neighborhood Hits	240	Shared Neighborhood Hits	104
SwissProt Accessions	Q80VP1, O70446	Gene names	Epn1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (Intersectin-EH-binding protein 1) (Ibp1).

CO5A3_HUMAN
NC score	0.092440 (rank : 379)	θ value	0.0961366 (rank : 306)
Query Neighborhood Hits	872	Target Neighborhood Hits	433	Shared Neighborhood Hits	141
SwissProt Accessions	P25940, Q9NZQ6	Gene names	COL5A3
Domain Architecture
Description	Collagen alpha-3(V) chain precursor.

TAB3_HUMAN
NC score	0.092385 (rank : 380)	θ value	0.000121331 (rank : 89)
Query Neighborhood Hits	872	Target Neighborhood Hits	168	Shared Neighborhood Hits	45
SwissProt Accessions	Q8N5C8, Q6VQR0	Gene names	MAP3K7IP3, TAB3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3) (NF-kappa-B-activating protein 1).

NEBU_HUMAN
NC score	0.092075 (rank : 381)	θ value	θ > 10 (rank : 1051)
Query Neighborhood Hits	872	Target Neighborhood Hits	420	Shared Neighborhood Hits	121
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

ANM2_HUMAN
NC score	0.091359 (rank : 382)	θ value	θ > 10 (rank : 876)
Query Neighborhood Hits	872	Target Neighborhood Hits	175	Shared Neighborhood Hits	97
SwissProt Accessions	P55345, P78350, Q9BW15, Q9UMC2	Gene names	PRMT2, HMT1, HRMT1L1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

CO9A3_HUMAN
NC score	0.091320 (rank : 383)	θ value	0.163984 (rank : 336)
Query Neighborhood Hits	872	Target Neighborhood Hits	361	Shared Neighborhood Hits	135
SwissProt Accessions	Q14050, Q13681, Q9H4G9, Q9UPE2	Gene names	COL9A3
Domain Architecture	No domain graphic available
Description	Collagen alpha-3(IX) chain precursor.

TAU_HUMAN
NC score	0.091263 (rank : 384)	θ value	θ > 10 (rank : 1125)
Query Neighborhood Hits	872	Target Neighborhood Hits	448	Shared Neighborhood Hits	172
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

CSKI1_HUMAN
NC score	0.091127 (rank : 385)	θ value	0.00390308 (rank : 160)
Query Neighborhood Hits	872	Target Neighborhood Hits	997	Shared Neighborhood Hits	288
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CO9A1_HUMAN
NC score	0.091110 (rank : 386)	θ value	0.163984 (rank : 335)
Query Neighborhood Hits	872	Target Neighborhood Hits	420	Shared Neighborhood Hits	137
SwissProt Accessions	P20849, Q13699, Q13700, Q5TF52, Q6P467, Q96BM8, Q99225, Q9H151, Q9H152, Q9Y6P2, Q9Y6P3	Gene names	COL9A1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

CO5A1_HUMAN
NC score	0.091091 (rank : 387)	θ value	0.125558 (rank : 320)
Query Neighborhood Hits	872	Target Neighborhood Hits	434	Shared Neighborhood Hits	142
SwissProt Accessions	P20908, Q15094, Q5SUX4	Gene names	COL5A1
Domain Architecture
Description	Collagen alpha-1(V) chain precursor.

MNT_HUMAN
NC score	0.091069 (rank : 388)	θ value	1.38821 (rank : 539)
Query Neighborhood Hits	872	Target Neighborhood Hits	496	Shared Neighborhood Hits	161
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

PRR13_MOUSE
NC score	0.090826 (rank : 389)	θ value	0.365318 (rank : 395)
Query Neighborhood Hits	872	Target Neighborhood Hits	54	Shared Neighborhood Hits	28
SwissProt Accessions	Q9CQJ5, Q3U3U4	Gene names	Prr13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

CO4A2_HUMAN
NC score	0.090662 (rank : 390)	θ value	θ > 10 (rank : 934)
Query Neighborhood Hits	872	Target Neighborhood Hits	454	Shared Neighborhood Hits	172
SwissProt Accessions	P08572	Gene names	COL4A2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

CRTC1_HUMAN
NC score	0.090587 (rank : 391)	θ value	0.813845 (rank : 456)
Query Neighborhood Hits	872	Target Neighborhood Hits	319	Shared Neighborhood Hits	135
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

CSKI2_MOUSE
NC score	0.090547 (rank : 392)	θ value	0.00869519 (rank : 187)
Query Neighborhood Hits	872	Target Neighborhood Hits	812	Shared Neighborhood Hits	230
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

ANM2_MOUSE
NC score	0.090468 (rank : 393)	θ value	θ > 10 (rank : 877)
Query Neighborhood Hits	872	Target Neighborhood Hits	175	Shared Neighborhood Hits	94
SwissProt Accessions	Q9R144	Gene names	Prmt2, Hrmt1l1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

COBA2_MOUSE
NC score	0.090459 (rank : 394)	θ value	3.0926 (rank : 634)
Query Neighborhood Hits	872	Target Neighborhood Hits	501	Shared Neighborhood Hits	162
SwissProt Accessions	Q64739, Q61432, Q9Z1W0	Gene names	Col11a2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

COGA1_HUMAN
NC score	0.090045 (rank : 395)	θ value	0.0193708 (rank : 224)
Query Neighborhood Hits	872	Target Neighborhood Hits	345	Shared Neighborhood Hits	117
SwissProt Accessions	Q07092	Gene names	COL16A1
Domain Architecture
Description	Collagen alpha-1(XVI) chain precursor.

HRBL_MOUSE
NC score	0.090031 (rank : 396)	θ value	θ > 10 (rank : 1014)
Query Neighborhood Hits	872	Target Neighborhood Hits	269	Shared Neighborhood Hits	129
SwissProt Accessions	Q80WC7, Q8BKS5, Q99J67	Gene names	Hrbl, Rabr
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

JPH2_HUMAN
NC score	0.090031 (rank : 397)	θ value	θ > 10 (rank : 1022)
Query Neighborhood Hits	872	Target Neighborhood Hits	639	Shared Neighborhood Hits	261
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

CO2A1_MOUSE
NC score	0.089343 (rank : 398)	θ value	1.38821 (rank : 529)
Query Neighborhood Hits	872	Target Neighborhood Hits	483	Shared Neighborhood Hits	156
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CO5A1_MOUSE
NC score	0.089170 (rank : 399)	θ value	0.0563607 (rank : 276)
Query Neighborhood Hits	872	Target Neighborhood Hits	419	Shared Neighborhood Hits	139
SwissProt Accessions	O88207	Gene names	Col5a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(V) chain precursor.

CO4A1_MOUSE
NC score	0.088986 (rank : 400)	θ value	1.81305 (rank : 560)
Query Neighborhood Hits	872	Target Neighborhood Hits	450	Shared Neighborhood Hits	157
SwissProt Accessions	P02463	Gene names	Col4a1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

SMRC1_HUMAN
NC score	0.088983 (rank : 401)	θ value	0.0330416 (rank : 255)
Query Neighborhood Hits	872	Target Neighborhood Hits	375	Shared Neighborhood Hits	80
SwissProt Accessions	Q92922, Q6P172, Q8IWH2	Gene names	SMARCC1, BAF155
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155).

PHC2_HUMAN
NC score	0.088948 (rank : 402)	θ value	1.81305 (rank : 580)
Query Neighborhood Hits	872	Target Neighborhood Hits	388	Shared Neighborhood Hits	153
SwissProt Accessions	Q8IXK0, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7	Gene names	PHC2, EDR2, PH2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2).

CO4A1_HUMAN
NC score	0.088838 (rank : 403)	θ value	3.0926 (rank : 633)
Query Neighborhood Hits	872	Target Neighborhood Hits	425	Shared Neighborhood Hits	156
SwissProt Accessions	P02462	Gene names	COL4A1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

GRP3_HUMAN
NC score	0.088756 (rank : 404)	θ value	θ > 10 (rank : 1010)
Query Neighborhood Hits	872	Target Neighborhood Hits	131	Shared Neighborhood Hits	25
SwissProt Accessions	Q8IV61, O94931	Gene names	RASGRP3, GRP3, KIAA0846
Domain Architecture
Description	RAS guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1).

FYB_HUMAN
NC score	0.088608 (rank : 405)	θ value	6.88961 (rank : 773)
Query Neighborhood Hits	872	Target Neighborhood Hits	379	Shared Neighborhood Hits	140
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

SMR3B_HUMAN
NC score	0.088096 (rank : 406)	θ value	6.88961 (rank : 791)
Query Neighborhood Hits	872	Target Neighborhood Hits	46	Shared Neighborhood Hits	20
SwissProt Accessions	P02814, Q9UBN0, Q9UCT0	Gene names	SMR3B, PBII, PROL3
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog B precursor (Proline-rich protein 3) (Proline-rich peptide P-B) [Contains: Peptide P-A; Peptide D1A].

TIAM1_MOUSE
NC score	0.087890 (rank : 407)	θ value	θ > 10 (rank : 1130)
Query Neighborhood Hits	872	Target Neighborhood Hits	205	Shared Neighborhood Hits	40
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

TARA_HUMAN
NC score	0.087747 (rank : 408)	θ value	θ > 10 (rank : 1124)
Query Neighborhood Hits	872	Target Neighborhood Hits	1626	Shared Neighborhood Hits	284
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

SMRC1_MOUSE
NC score	0.087710 (rank : 409)	θ value	0.0961366 (rank : 313)
Query Neighborhood Hits	872	Target Neighborhood Hits	459	Shared Neighborhood Hits	87
SwissProt Accessions	P97496, Q7TS80, Q7TT29	Gene names	Smarcc1, Baf155, Srg3
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155) (SWI3-related protein).

PER3_HUMAN
NC score	0.087605 (rank : 410)	θ value	2.36792 (rank : 611)
Query Neighborhood Hits	872	Target Neighborhood Hits	479	Shared Neighborhood Hits	182
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

PKHG1_HUMAN
NC score	0.087579 (rank : 411)	θ value	θ > 10 (rank : 1072)
Query Neighborhood Hits	872	Target Neighborhood Hits	174	Shared Neighborhood Hits	40
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

MLL4_HUMAN
NC score	0.087432 (rank : 412)	θ value	0.00665767 (rank : 182)
Query Neighborhood Hits	872	Target Neighborhood Hits	722	Shared Neighborhood Hits	188
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

RPB1_MOUSE
NC score	0.087429 (rank : 413)	θ value	0.000786445 (rank : 121)
Query Neighborhood Hits	872	Target Neighborhood Hits	363	Shared Neighborhood Hits	89
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

TAU_MOUSE
NC score	0.087305 (rank : 414)	θ value	4.03905 (rank : 699)
Query Neighborhood Hits	872	Target Neighborhood Hits	502	Shared Neighborhood Hits	163
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

ARHGG_HUMAN
NC score	0.087218 (rank : 415)	θ value	θ > 10 (rank : 895)
Query Neighborhood Hits	872	Target Neighborhood Hits	129	Shared Neighborhood Hits	50
SwissProt Accessions	Q5VV41, Q86TF0, Q99434	Gene names	ARHGEF16, NBR
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

RPB1_HUMAN
NC score	0.086927 (rank : 416)	θ value	0.000786445 (rank : 120)
Query Neighborhood Hits	872	Target Neighborhood Hits	362	Shared Neighborhood Hits	89
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

FGD1_MOUSE
NC score	0.086837 (rank : 417)	θ value	1.81305 (rank : 564)
Query Neighborhood Hits	872	Target Neighborhood Hits	387	Shared Neighborhood Hits	143
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

CENB2_HUMAN
NC score	0.086433 (rank : 418)	θ value	θ > 10 (rank : 919)
Query Neighborhood Hits	872	Target Neighborhood Hits	425	Shared Neighborhood Hits	39
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

FGD1_HUMAN
NC score	0.086431 (rank : 419)	θ value	0.00509761 (rank : 170)
Query Neighborhood Hits	872	Target Neighborhood Hits	367	Shared Neighborhood Hits	111
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

ZN645_HUMAN
NC score	0.086413 (rank : 420)	θ value	θ > 10 (rank : 1141)
Query Neighborhood Hits	872	Target Neighborhood Hits	265	Shared Neighborhood Hits	110
SwissProt Accessions	Q8N7E2, Q6DJY9	Gene names	ZNF645
Domain Architecture	No domain graphic available
Description	Zinc finger protein 645.

PI5PA_MOUSE
NC score	0.086397 (rank : 421)	θ value	2.36792 (rank : 613)
Query Neighborhood Hits	872	Target Neighborhood Hits	331	Shared Neighborhood Hits	124
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

3BP2_HUMAN
NC score	0.086324 (rank : 422)	θ value	6.88961 (rank : 749)
Query Neighborhood Hits	872	Target Neighborhood Hits	296	Shared Neighborhood Hits	122
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

MTSS1_HUMAN
NC score	0.086323 (rank : 423)	θ value	θ > 10 (rank : 1043)
Query Neighborhood Hits	872	Target Neighborhood Hits	504	Shared Neighborhood Hits	179
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

RTP3_MOUSE
NC score	0.086301 (rank : 424)	θ value	θ > 10 (rank : 1088)
Query Neighborhood Hits	872	Target Neighborhood Hits	374	Shared Neighborhood Hits	128
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

RIMB2_HUMAN
NC score	0.086115 (rank : 425)	θ value	θ > 10 (rank : 1085)
Query Neighborhood Hits	872	Target Neighborhood Hits	263	Shared Neighborhood Hits	107
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

CO4A5_HUMAN
NC score	0.085962 (rank : 426)	θ value	1.06291 (rank : 487)
Query Neighborhood Hits	872	Target Neighborhood Hits	383	Shared Neighborhood Hits	143
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

COBA2_HUMAN
NC score	0.085935 (rank : 427)	θ value	1.81305 (rank : 561)
Query Neighborhood Hits	872	Target Neighborhood Hits	408	Shared Neighborhood Hits	127
SwissProt Accessions	P13942, Q07751, Q13271, Q13272, Q13273, Q99866, Q9UIP9	Gene names	COL11A2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

COHA1_MOUSE
NC score	0.085805 (rank : 428)	θ value	0.813845 (rank : 455)
Query Neighborhood Hits	872	Target Neighborhood Hits	414	Shared Neighborhood Hits	141
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

CENB5_HUMAN
NC score	0.085518 (rank : 429)	θ value	θ > 10 (rank : 920)
Query Neighborhood Hits	872	Target Neighborhood Hits	395	Shared Neighborhood Hits	37
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

EPN1_HUMAN
NC score	0.085232 (rank : 430)	θ value	0.0113563 (rank : 201)
Query Neighborhood Hits	872	Target Neighborhood Hits	206	Shared Neighborhood Hits	80
SwissProt Accessions	Q9Y6I3, Q86ST3, Q9HA18	Gene names	EPN1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (EH domain-binding mitotic phosphoprotein).

CTDP1_HUMAN
NC score	0.085195 (rank : 431)	θ value	θ > 10 (rank : 958)
Query Neighborhood Hits	872	Target Neighborhood Hits	416	Shared Neighborhood Hits	165
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

DIAP1_HUMAN
NC score	0.084888 (rank : 432)	θ value	0.0113563 (rank : 200)
Query Neighborhood Hits	872	Target Neighborhood Hits	784	Shared Neighborhood Hits	133
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

SNX18_HUMAN
NC score	0.084876 (rank : 433)	θ value	6.88961 (rank : 792)
Query Neighborhood Hits	872	Target Neighborhood Hits	207	Shared Neighborhood Hits	100
SwissProt Accessions	Q96RF0	Gene names	SNAG1, SNX18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

PRRT1_MOUSE
NC score	0.084795 (rank : 434)	θ value	0.0431538 (rank : 266)
Query Neighborhood Hits	872	Target Neighborhood Hits	102	Shared Neighborhood Hits	40
SwissProt Accessions	O35449	Gene names	Prrt1, Ng5
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 1.

MYO15_MOUSE
NC score	0.084758 (rank : 435)	θ value	1.06291 (rank : 504)
Query Neighborhood Hits	872	Target Neighborhood Hits	467	Shared Neighborhood Hits	197
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

CSKI2_HUMAN
NC score	0.084548 (rank : 436)	θ value	9.92553e-07 (rank : 65)
Query Neighborhood Hits	872	Target Neighborhood Hits	747	Shared Neighborhood Hits	182
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

PRG4_HUMAN
NC score	0.084465 (rank : 437)	θ value	0.0148317 (rank : 214)
Query Neighborhood Hits	872	Target Neighborhood Hits	764	Shared Neighborhood Hits	148
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

MBB1A_HUMAN
NC score	0.084459 (rank : 438)	θ value	θ > 10 (rank : 1037)
Query Neighborhood Hits	872	Target Neighborhood Hits	665	Shared Neighborhood Hits	184
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

PDZD2_HUMAN
NC score	0.084428 (rank : 439)	θ value	0.0431538 (rank : 265)
Query Neighborhood Hits	872	Target Neighborhood Hits	772	Shared Neighborhood Hits	198
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

CD248_HUMAN
NC score	0.084382 (rank : 440)	θ value	θ > 10 (rank : 910)
Query Neighborhood Hits	872	Target Neighborhood Hits	679	Shared Neighborhood Hits	199
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

RIMB2_MOUSE
NC score	0.084358 (rank : 441)	θ value	θ > 10 (rank : 1086)
Query Neighborhood Hits	872	Target Neighborhood Hits	246	Shared Neighborhood Hits	95
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

ATX7_MOUSE
NC score	0.084295 (rank : 442)	θ value	θ > 10 (rank : 899)
Query Neighborhood Hits	872	Target Neighborhood Hits	328	Shared Neighborhood Hits	163
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

PRR13_HUMAN
NC score	0.084281 (rank : 443)	θ value	3.0926 (rank : 657)
Query Neighborhood Hits	872	Target Neighborhood Hits	105	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

PRRT1_HUMAN
NC score	0.083912 (rank : 444)	θ value	0.0193708 (rank : 230)
Query Neighborhood Hits	872	Target Neighborhood Hits	94	Shared Neighborhood Hits	38
SwissProt Accessions	Q99946, Q96DW3, Q96NQ8	Gene names	PRRT1, C6orf31, NG5
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 1.

K1683_HUMAN
NC score	0.083803 (rank : 445)	θ value	θ > 10 (rank : 1024)
Query Neighborhood Hits	872	Target Neighborhood Hits	240	Shared Neighborhood Hits	90
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

ARHGA_MOUSE
NC score	0.083684 (rank : 446)	θ value	θ > 10 (rank : 890)
Query Neighborhood Hits	872	Target Neighborhood Hits	125	Shared Neighborhood Hits	34
SwissProt Accessions	Q8C033, Q5DU38, Q80VH8, Q8BW76, Q922S7	Gene names	Arhgef10, Kiaa0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

CENG1_MOUSE
NC score	0.083564 (rank : 447)	θ value	0.000158464 (rank : 91)
Query Neighborhood Hits	872	Target Neighborhood Hits	531	Shared Neighborhood Hits	78
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

COIA1_MOUSE
NC score	0.083405 (rank : 448)	θ value	3.0926 (rank : 635)
Query Neighborhood Hits	872	Target Neighborhood Hits	481	Shared Neighborhood Hits	155
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

GA2L2_MOUSE
NC score	0.083341 (rank : 449)	θ value	θ > 10 (rank : 996)
Query Neighborhood Hits	872	Target Neighborhood Hits	395	Shared Neighborhood Hits	169
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

DIAP1_MOUSE
NC score	0.083208 (rank : 450)	θ value	0.000786445 (rank : 118)
Query Neighborhood Hits	872	Target Neighborhood Hits	839	Shared Neighborhood Hits	128
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

RP1L1_HUMAN
NC score	0.082986 (rank : 451)	θ value	0.00665767 (rank : 184)
Query Neighborhood Hits	872	Target Neighborhood Hits	1072	Shared Neighborhood Hits	198
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

BIN1_HUMAN
NC score	0.082914 (rank : 452)	θ value	6.88961 (rank : 756)
Query Neighborhood Hits	872	Target Neighborhood Hits	335	Shared Neighborhood Hits	140
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

SNX18_MOUSE
NC score	0.082852 (rank : 453)	θ value	θ > 10 (rank : 1104)
Query Neighborhood Hits	872	Target Neighborhood Hits	198	Shared Neighborhood Hits	96
SwissProt Accessions	Q91ZR2	Gene names	Snag1, Snx18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

ARHGF_HUMAN
NC score	0.082720 (rank : 454)	θ value	θ > 10 (rank : 894)
Query Neighborhood Hits	872	Target Neighborhood Hits	214	Shared Neighborhood Hits	84
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

ARHGA_HUMAN
NC score	0.082597 (rank : 455)	θ value	θ > 10 (rank : 889)
Query Neighborhood Hits	872	Target Neighborhood Hits	187	Shared Neighborhood Hits	33
SwissProt Accessions	O15013, O14665, Q68D55, Q8IWD9, Q8IY77	Gene names	ARHGEF10, KIAA0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

CCD1A_HUMAN
NC score	0.082430 (rank : 456)	θ value	8.40245e-06 (rank : 74)
Query Neighborhood Hits	872	Target Neighborhood Hits	123	Shared Neighborhood Hits	35
SwissProt Accessions	Q6P1N0, Q7Z435, Q86XV0, Q8NF89, Q9H603, Q9NXI1	Gene names	CC2D1A
Domain Architecture	No domain graphic available
Description	Coiled-coil and C2 domain-containing protein 1A (Five repressor element under dual repression-binding protein 1) (FRE under dual repression-binding protein 1) (Freud-1) (Putative NF-kappa-B- activating protein 023N).

PRP5_HUMAN
NC score	0.081912 (rank : 457)	θ value	θ > 10 (rank : 1079)
Query Neighborhood Hits	872	Target Neighborhood Hits	108	Shared Neighborhood Hits	54
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

AB1IP_HUMAN
NC score	0.081252 (rank : 458)	θ value	0.00134147 (rank : 133)
Query Neighborhood Hits	872	Target Neighborhood Hits	213	Shared Neighborhood Hits	71
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

CCNK_MOUSE
NC score	0.081075 (rank : 459)	θ value	0.0113563 (rank : 197)
Query Neighborhood Hits	872	Target Neighborhood Hits	350	Shared Neighborhood Hits	113
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

BAZ2A_MOUSE
NC score	0.081063 (rank : 460)	θ value	0.21417 (rank : 360)
Query Neighborhood Hits	872	Target Neighborhood Hits	744	Shared Neighborhood Hits	191
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

ALEX_MOUSE
NC score	0.080835 (rank : 461)	θ value	0.163984 (rank : 330)
Query Neighborhood Hits	872	Target Neighborhood Hits	197	Shared Neighborhood Hits	72
SwissProt Accessions	Q6R0H6, Q8BIR3	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

CO1A2_HUMAN
NC score	0.080808 (rank : 462)	θ value	0.813845 (rank : 452)
Query Neighborhood Hits	872	Target Neighborhood Hits	329	Shared Neighborhood Hits	118
SwissProt Accessions	P08123, P02464, Q9UEB6, Q9UPH0	Gene names	COL1A2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

RUSC2_HUMAN
NC score	0.080581 (rank : 463)	θ value	0.365318 (rank : 396)
Query Neighborhood Hits	872	Target Neighborhood Hits	205	Shared Neighborhood Hits	86
SwissProt Accessions	Q8N2Y8, O15080, Q6P1W7	Gene names	RUSC2, KIAA0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

RIMB1_HUMAN
NC score	0.080536 (rank : 464)	θ value	θ > 10 (rank : 1084)
Query Neighborhood Hits	872	Target Neighborhood Hits	1479	Shared Neighborhood Hits	274
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

CO8A1_HUMAN
NC score	0.080460 (rank : 465)	θ value	0.0193708 (rank : 223)
Query Neighborhood Hits	872	Target Neighborhood Hits	288	Shared Neighborhood Hits	103
SwissProt Accessions	P27658, Q96D07	Gene names	COL8A1
Domain Architecture
Description	Collagen alpha-1(VIII) chain precursor (Endothelial collagen).

CENB1_HUMAN
NC score	0.080283 (rank : 466)	θ value	θ > 10 (rank : 918)
Query Neighborhood Hits	872	Target Neighborhood Hits	383	Shared Neighborhood Hits	41
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

MAP1A_HUMAN
NC score	0.080229 (rank : 467)	θ value	θ > 10 (rank : 1032)
Query Neighborhood Hits	872	Target Neighborhood Hits	1626	Shared Neighborhood Hits	299
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

COIA1_HUMAN
NC score	0.080197 (rank : 468)	θ value	θ > 10 (rank : 946)
Query Neighborhood Hits	872	Target Neighborhood Hits	447	Shared Neighborhood Hits	162
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

SET1A_HUMAN
NC score	0.080015 (rank : 469)	θ value	0.47712 (rank : 420)
Query Neighborhood Hits	872	Target Neighborhood Hits	690	Shared Neighborhood Hits	144
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

ECT2_HUMAN
NC score	0.079916 (rank : 470)	θ value	θ > 10 (rank : 969)
Query Neighborhood Hits	872	Target Neighborhood Hits	98	Shared Neighborhood Hits	33
SwissProt Accessions	Q9H8V3, Q9NSV8, Q9NVW9	Gene names	ECT2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

GNRP_MOUSE
NC score	0.079724 (rank : 471)	θ value	θ > 10 (rank : 1007)
Query Neighborhood Hits	872	Target Neighborhood Hits	191	Shared Neighborhood Hits	44
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

ECT2_MOUSE
NC score	0.079659 (rank : 472)	θ value	θ > 10 (rank : 970)
Query Neighborhood Hits	872	Target Neighborhood Hits	98	Shared Neighborhood Hits	31
SwissProt Accessions	Q07139	Gene names	Ect2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

CO8A2_HUMAN
NC score	0.079619 (rank : 473)	θ value	6.88961 (rank : 762)
Query Neighborhood Hits	872	Target Neighborhood Hits	299	Shared Neighborhood Hits	125
SwissProt Accessions	P25067, Q8TEJ5	Gene names	COL8A2
Domain Architecture
Description	Collagen alpha-2(VIII) chain precursor (Endothelial collagen).

WBS14_HUMAN
NC score	0.079468 (rank : 474)	θ value	0.000270298 (rank : 104)
Query Neighborhood Hits	872	Target Neighborhood Hits	273	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

AMPH_HUMAN
NC score	0.079355 (rank : 475)	θ value	θ > 10 (rank : 873)
Query Neighborhood Hits	872	Target Neighborhood Hits	455	Shared Neighborhood Hits	141
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

COAA1_MOUSE
NC score	0.079333 (rank : 476)	θ value	0.62314 (rank : 429)
Query Neighborhood Hits	872	Target Neighborhood Hits	286	Shared Neighborhood Hits	107
SwissProt Accessions	Q05306	Gene names	Col10a1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

JADE2_MOUSE
NC score	0.079204 (rank : 477)	θ value	1.38821 (rank : 536)
Query Neighborhood Hits	872	Target Neighborhood Hits	560	Shared Neighborhood Hits	193
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

CO8A2_MOUSE
NC score	0.079195 (rank : 478)	θ value	0.47712 (rank : 403)
Query Neighborhood Hits	872	Target Neighborhood Hits	273	Shared Neighborhood Hits	116
SwissProt Accessions	P25318, Q68ED0, Q6KAQ4, Q6P1C4	Gene names	Col8a2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(VIII) chain precursor (Endothelial collagen).

BIN1_MOUSE
NC score	0.078965 (rank : 479)	θ value	0.279714 (rank : 371)
Query Neighborhood Hits	872	Target Neighborhood Hits	283	Shared Neighborhood Hits	115
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

IF4G1_MOUSE
NC score	0.078703 (rank : 480)	θ value	θ > 10 (rank : 1016)
Query Neighborhood Hits	872	Target Neighborhood Hits	534	Shared Neighborhood Hits	216
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

ARHG3_HUMAN
NC score	0.078398 (rank : 481)	θ value	θ > 10 (rank : 884)
Query Neighborhood Hits	872	Target Neighborhood Hits	82	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NR81, Q6NUN3, Q7Z4U2, Q7Z5T2, Q9H7T4	Gene names	ARHGEF3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3 (Exchange factor found in platelets and leukemic and neuronal tissues) (XPLN).

TCRG1_MOUSE
NC score	0.078397 (rank : 482)	θ value	3.0926 (rank : 664)
Query Neighborhood Hits	872	Target Neighborhood Hits	947	Shared Neighborhood Hits	128
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

DOK2_MOUSE
NC score	0.078381 (rank : 483)	θ value	θ > 10 (rank : 968)
Query Neighborhood Hits	872	Target Neighborhood Hits	244	Shared Neighborhood Hits	140
SwissProt Accessions	O70469, O70272, Q99KL1	Gene names	Dok2, Frip
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)) (Dok- related protein) (Dok-R) (IL-four receptor-interacting protein) (FRIP).

CO8A1_MOUSE
NC score	0.078117 (rank : 484)	θ value	0.0252991 (rank : 237)
Query Neighborhood Hits	872	Target Neighborhood Hits	251	Shared Neighborhood Hits	95
SwissProt Accessions	Q00780, Q9D2V4	Gene names	Col8a1
Domain Architecture
Description	Collagen alpha-1(VIII) chain precursor.

OBF1_HUMAN
NC score	0.078059 (rank : 485)	θ value	θ > 10 (rank : 1060)
Query Neighborhood Hits	872	Target Neighborhood Hits	203	Shared Neighborhood Hits	114
SwissProt Accessions	Q16633, Q14983	Gene names	POU2AF1, OBF1
Domain Architecture	No domain graphic available
Description	POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (OCT-binding factor 1) (BOB-1) (OCA-B).

CENG1_HUMAN
NC score	0.077884 (rank : 486)	θ value	0.00102713 (rank : 125)
Query Neighborhood Hits	872	Target Neighborhood Hits	544	Shared Neighborhood Hits	76
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

ARHG3_MOUSE
NC score	0.077826 (rank : 487)	θ value	θ > 10 (rank : 885)
Query Neighborhood Hits	872	Target Neighborhood Hits	85	Shared Neighborhood Hits	31
SwissProt Accessions	Q91X46, Q8CDM0, Q91VY4, Q99K14, Q9DC31	Gene names	Arhgef3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3.

TXND2_HUMAN
NC score	0.077731 (rank : 488)	θ value	θ > 10 (rank : 1137)
Query Neighborhood Hits	872	Target Neighborhood Hits	793	Shared Neighborhood Hits	143
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

CSPG5_MOUSE
NC score	0.077471 (rank : 489)	θ value	0.279714 (rank : 375)
Query Neighborhood Hits	872	Target Neighborhood Hits	211	Shared Neighborhood Hits	75
SwissProt Accessions	Q71M36, Q71M37, Q7TNT8, Q8BPJ5, Q9QY32	Gene names	Cspg5, Caleb, Ngc
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

CO4A6_HUMAN
NC score	0.077417 (rank : 490)	θ value	θ > 10 (rank : 936)
Query Neighborhood Hits	872	Target Neighborhood Hits	318	Shared Neighborhood Hits	110
SwissProt Accessions	Q14031, Q12823, Q14053, Q5JYH6, Q9NQM5, Q9NTX3, Q9UJ76, Q9UMG6, Q9Y4L4	Gene names	COL4A6
Domain Architecture
Description	Collagen alpha-6(IV) chain precursor.

SEPT9_HUMAN
NC score	0.077308 (rank : 491)	θ value	1.06291 (rank : 510)
Query Neighborhood Hits	872	Target Neighborhood Hits	706	Shared Neighborhood Hits	221
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

COAA1_HUMAN
NC score	0.077289 (rank : 492)	θ value	6.88961 (rank : 763)
Query Neighborhood Hits	872	Target Neighborhood Hits	316	Shared Neighborhood Hits	114
SwissProt Accessions	Q03692	Gene names	COL10A1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

CO7A1_HUMAN
NC score	0.076919 (rank : 493)	θ value	θ > 10 (rank : 942)
Query Neighborhood Hits	872	Target Neighborhood Hits	807	Shared Neighborhood Hits	194
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

COHA1_HUMAN
NC score	0.076839 (rank : 494)	θ value	θ > 10 (rank : 945)
Query Neighborhood Hits	872	Target Neighborhood Hits	400	Shared Neighborhood Hits	132
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

RBM12_MOUSE
NC score	0.076743 (rank : 495)	θ value	0.125558 (rank : 323)
Query Neighborhood Hits	872	Target Neighborhood Hits	313	Shared Neighborhood Hits	107
SwissProt Accessions	Q8R4X3, Q8K373, Q8R302, Q9CS80	Gene names	Rbm12
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

CI079_HUMAN
NC score	0.076578 (rank : 496)	θ value	4.03905 (rank : 676)
Query Neighborhood Hits	872	Target Neighborhood Hits	288	Shared Neighborhood Hits	93
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

CO9A2_MOUSE
NC score	0.076503 (rank : 497)	θ value	θ > 10 (rank : 944)
Query Neighborhood Hits	872	Target Neighborhood Hits	279	Shared Neighborhood Hits	102
SwissProt Accessions	Q07643	Gene names	Col9a2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(IX) chain precursor.

COJA1_HUMAN
NC score	0.076386 (rank : 498)	θ value	θ > 10 (rank : 947)
Query Neighborhood Hits	872	Target Neighborhood Hits	323	Shared Neighborhood Hits	115
SwissProt Accessions	Q14993, Q00559, Q05850, Q12885, Q13676, Q5JUF0, Q5T424, Q9H572, Q9NPZ2, Q9NQP2	Gene names	COL19A1
Domain Architecture
Description	Collagen alpha-1(XIX) chain precursor (Collagen alpha-1(Y) chain).

TENS1_HUMAN
NC score	0.076372 (rank : 499)	θ value	0.00298849 (rank : 157)
Query Neighborhood Hits	872	Target Neighborhood Hits	400	Shared Neighborhood Hits	119
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

ARHG8_MOUSE
NC score	0.076355 (rank : 500)	θ value	θ > 10 (rank : 888)
Query Neighborhood Hits	872	Target Neighborhood Hits	79	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Z206, Q8C4I0, Q9Z1L7	Gene names	Net1, Arhgef8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (Rho guanine nucleotide exchange factor 8).

EMID2_MOUSE
NC score	0.076306 (rank : 501)	θ value	0.0736092 (rank : 293)
Query Neighborhood Hits	872	Target Neighborhood Hits	201	Shared Neighborhood Hits	86
SwissProt Accessions	Q91VF6, Q8K4P3	Gene names	Emid2, Col26a, Col26a1, Emu2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXVI) chain precursor (EMI domain-containing protein 2) (Protein Emu2) (Emilin and multimerin domain-containing protein 2).

ARHG8_HUMAN
NC score	0.076181 (rank : 502)	θ value	θ > 10 (rank : 887)
Query Neighborhood Hits	872	Target Neighborhood Hits	85	Shared Neighborhood Hits	30
SwissProt Accessions	Q7Z628, Q12773, Q96D82, Q99903, Q9UEN6	Gene names	NET1, ARHGEF8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (p65 Net1 proto- oncogene) (Rho guanine nucleotide exchange factor 8).

PDCD7_HUMAN
NC score	0.076089 (rank : 503)	θ value	0.00869519 (rank : 190)
Query Neighborhood Hits	872	Target Neighborhood Hits	255	Shared Neighborhood Hits	60
SwissProt Accessions	Q8N8D1, Q96AK8, Q9Y6D7	Gene names	PDCD7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18) (HES18).

SOX13_HUMAN
NC score	0.076013 (rank : 504)	θ value	θ > 10 (rank : 1108)
Query Neighborhood Hits	872	Target Neighborhood Hits	464	Shared Neighborhood Hits	169
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

TACC3_HUMAN
NC score	0.075865 (rank : 505)	θ value	0.00509761 (rank : 176)
Query Neighborhood Hits	872	Target Neighborhood Hits	779	Shared Neighborhood Hits	118
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

ZIMP7_HUMAN
NC score	0.075683 (rank : 506)	θ value	1.06291 (rank : 522)
Query Neighborhood Hits	872	Target Neighborhood Hits	290	Shared Neighborhood Hits	130
SwissProt Accessions	Q8NF64, O94790, Q659A8, Q6JKL5, Q8WTX8, Q96Q01, Q9BQH7	Gene names	ZIMP7, KIAA1886
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

NUP53_HUMAN
NC score	0.075265 (rank : 507)	θ value	θ > 10 (rank : 1059)
Query Neighborhood Hits	872	Target Neighborhood Hits	156	Shared Neighborhood Hits	101
SwissProt Accessions	Q8NFH5, Q4ZFZ9, Q53S95, Q8TDJ1	Gene names	NUP35, MP44, NUP53
Domain Architecture	No domain graphic available
Description	Nucleoporin NUP53 (Nuclear pore complex protein Nup53) (Nucleoporin Nup35) (35 kDa nucleoporin) (Mitotic phosphoprotein 44) (MP-44).

GNRP_HUMAN
NC score	0.074895 (rank : 508)	θ value	θ > 10 (rank : 1006)
Query Neighborhood Hits	872	Target Neighborhood Hits	239	Shared Neighborhood Hits	44
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

MNT_MOUSE
NC score	0.074870 (rank : 509)	θ value	0.365318 (rank : 393)
Query Neighborhood Hits	872	Target Neighborhood Hits	432	Shared Neighborhood Hits	114
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

CAC1G_HUMAN
NC score	0.074779 (rank : 510)	θ value	0.813845 (rank : 451)
Query Neighborhood Hits	872	Target Neighborhood Hits	587	Shared Neighborhood Hits	225
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

PKHA6_HUMAN
NC score	0.074694 (rank : 511)	θ value	θ > 10 (rank : 1070)
Query Neighborhood Hits	872	Target Neighborhood Hits	556	Shared Neighborhood Hits	146
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

COFA1_HUMAN
NC score	0.074272 (rank : 512)	θ value	0.279714 (rank : 374)
Query Neighborhood Hits	872	Target Neighborhood Hits	292	Shared Neighborhood Hits	98
SwissProt Accessions	P39059, Q5T6J4, Q9Y4W4	Gene names	COL15A1
Domain Architecture
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV) (Restin) (Related to endostatin)].

P55G_HUMAN
NC score	0.074085 (rank : 513)	θ value	θ > 10 (rank : 1061)
Query Neighborhood Hits	872	Target Neighborhood Hits	451	Shared Neighborhood Hits	40
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

EP400_MOUSE
NC score	0.073981 (rank : 514)	θ value	1.43324e-05 (rank : 77)
Query Neighborhood Hits	872	Target Neighborhood Hits	592	Shared Neighborhood Hits	154
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

PCQAP_HUMAN
NC score	0.073503 (rank : 515)	θ value	2.36792 (rank : 609)
Query Neighborhood Hits	872	Target Neighborhood Hits	549	Shared Neighborhood Hits	110
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

ATX7_HUMAN
NC score	0.073482 (rank : 516)	θ value	θ > 10 (rank : 898)
Query Neighborhood Hits	872	Target Neighborhood Hits	351	Shared Neighborhood Hits	144
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

RC3H1_HUMAN
NC score	0.073383 (rank : 517)	θ value	8.99809 (rank : 855)
Query Neighborhood Hits	872	Target Neighborhood Hits	433	Shared Neighborhood Hits	141
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

WASP_MOUSE
NC score	0.073288 (rank : 518)	θ value	5.27518 (rank : 747)
Query Neighborhood Hits	872	Target Neighborhood Hits	223	Shared Neighborhood Hits	91
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

CSTFT_MOUSE
NC score	0.073215 (rank : 519)	θ value	1.17247e-07 (rank : 60)
Query Neighborhood Hits	872	Target Neighborhood Hits	356	Shared Neighborhood Hits	91
SwissProt Accessions	Q8C7E9, Q6A016, Q8BHH7, Q8C3W7, Q8R2Y1, Q9EPU3	Gene names	Cstf2t, Kiaa0689
Domain Architecture	No domain graphic available
Description	Cleavage stimulation factor 64 kDa subunit, tau variant (CSTF 64 kDa subunit, tau variant) (CF-1 64 kDa subunit, tau variant) (TauCstF-64).

PHLB1_HUMAN
NC score	0.072893 (rank : 520)	θ value	4.03905 (rank : 691)
Query Neighborhood Hits	872	Target Neighborhood Hits	1038	Shared Neighborhood Hits	204
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

TGON2_HUMAN
NC score	0.072820 (rank : 521)	θ value	θ > 10 (rank : 1129)
Query Neighborhood Hits	872	Target Neighborhood Hits	1037	Shared Neighborhood Hits	186
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TCRG1_HUMAN
NC score	0.072816 (rank : 522)	θ value	4.03905 (rank : 700)
Query Neighborhood Hits	872	Target Neighborhood Hits	929	Shared Neighborhood Hits	117
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TROAP_HUMAN
NC score	0.072755 (rank : 523)	θ value	θ > 10 (rank : 1134)
Query Neighborhood Hits	872	Target Neighborhood Hits	258	Shared Neighborhood Hits	119
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

DAPP1_MOUSE
NC score	0.072480 (rank : 524)	θ value	θ > 10 (rank : 961)
Query Neighborhood Hits	872	Target Neighborhood Hits	225	Shared Neighborhood Hits	40
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

CONA1_HUMAN
NC score	0.072282 (rank : 525)	θ value	θ > 10 (rank : 949)
Query Neighborhood Hits	872	Target Neighborhood Hits	281	Shared Neighborhood Hits	101
SwissProt Accessions	Q86Y22, Q8IVR4, Q9NT93	Gene names	COL23A1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

P55G_MOUSE
NC score	0.072174 (rank : 526)	θ value	θ > 10 (rank : 1062)
Query Neighborhood Hits	872	Target Neighborhood Hits	401	Shared Neighborhood Hits	36
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

DDFL1_HUMAN
NC score	0.072067 (rank : 527)	θ value	θ > 10 (rank : 966)
Query Neighborhood Hits	872	Target Neighborhood Hits	353	Shared Neighborhood Hits	44
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

IRS2_HUMAN
NC score	0.071984 (rank : 528)	θ value	0.0193708 (rank : 228)
Query Neighborhood Hits	872	Target Neighborhood Hits	262	Shared Neighborhood Hits	87
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

SF3B4_HUMAN
NC score	0.071926 (rank : 529)	θ value	1.87187e-05 (rank : 81)
Query Neighborhood Hits	872	Target Neighborhood Hits	445	Shared Neighborhood Hits	111
SwissProt Accessions	Q15427	Gene names	SF3B4, SAP49
Domain Architecture
Description	Splicing factor 3B subunit 4 (Spliceosome-associated protein 49) (SAP 49) (SF3b50) (Pre-mRNA-splicing factor SF3b 49 kDa subunit).

TM108_MOUSE
NC score	0.071740 (rank : 530)	θ value	θ > 10 (rank : 1131)
Query Neighborhood Hits	872	Target Neighborhood Hits	336	Shared Neighborhood Hits	121
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

SYP2L_HUMAN
NC score	0.071676 (rank : 531)	θ value	0.21417 (rank : 369)
Query Neighborhood Hits	872	Target Neighborhood Hits	400	Shared Neighborhood Hits	133
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

COFA1_MOUSE
NC score	0.071658 (rank : 532)	θ value	8.99809 (rank : 811)
Query Neighborhood Hits	872	Target Neighborhood Hits	305	Shared Neighborhood Hits	100
SwissProt Accessions	O35206, Q9EQD9	Gene names	Col15a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV)].

FHOD1_MOUSE
NC score	0.071446 (rank : 533)	θ value	3.0926 (rank : 643)
Query Neighborhood Hits	872	Target Neighborhood Hits	217	Shared Neighborhood Hits	93
SwissProt Accessions	Q6P9Q4, Q8BMK2	Gene names	Fhod1, Fhos1
Domain Architecture	No domain graphic available
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

TARA_MOUSE
NC score	0.071262 (rank : 534)	θ value	0.365318 (rank : 397)
Query Neighborhood Hits	872	Target Neighborhood Hits	1133	Shared Neighborhood Hits	167
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

PO121_MOUSE
NC score	0.071135 (rank : 535)	θ value	3.0926 (rank : 656)
Query Neighborhood Hits	872	Target Neighborhood Hits	345	Shared Neighborhood Hits	92
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

WASP_HUMAN
NC score	0.071090 (rank : 536)	θ value	4.03905 (rank : 704)
Query Neighborhood Hits	872	Target Neighborhood Hits	195	Shared Neighborhood Hits	86
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

EMID2_HUMAN
NC score	0.071043 (rank : 537)	θ value	θ > 10 (rank : 975)
Query Neighborhood Hits	872	Target Neighborhood Hits	226	Shared Neighborhood Hits	95
SwissProt Accessions	Q96A83	Gene names	EMID2, COL26A1, EMU2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXVI) chain precursor (EMI domain-containing protein 2) (Protein Emu2) (Emilin and multimerin domain-containing protein 2).

DAPP1_HUMAN
NC score	0.070644 (rank : 538)	θ value	θ > 10 (rank : 960)
Query Neighborhood Hits	872	Target Neighborhood Hits	227	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

PKHA6_MOUSE
NC score	0.070505 (rank : 539)	θ value	θ > 10 (rank : 1071)
Query Neighborhood Hits	872	Target Neighborhood Hits	591	Shared Neighborhood Hits	135
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

EMID1_HUMAN
NC score	0.070402 (rank : 540)	θ value	1.81305 (rank : 563)
Query Neighborhood Hits	872	Target Neighborhood Hits	215	Shared Neighborhood Hits	92
SwissProt Accessions	Q96A84, Q6ICG1, Q86SS7	Gene names	EMID1, EMU1
Domain Architecture	No domain graphic available
Description	EMI domain-containing protein 1 precursor (Protein Emu1) (Emilin and multimerin domain-containing protein 1).

MCF2_HUMAN
NC score	0.070250 (rank : 541)	θ value	θ > 10 (rank : 1039)
Query Neighborhood Hits	872	Target Neighborhood Hits	166	Shared Neighborhood Hits	37
SwissProt Accessions	P10911, P14919, Q5JYJ4, Q8IUF3, Q8IUF4, Q9UJB3	Gene names	MCF2, DBL
Domain Architecture
Description	Proto-oncogene DBL (Proto-oncogene MCF-2) [Contains: MCF2-transforming protein; DBL-transforming protein].

CSPG5_HUMAN
NC score	0.070112 (rank : 542)	θ value	1.38821 (rank : 530)
Query Neighborhood Hits	872	Target Neighborhood Hits	199	Shared Neighborhood Hits	84
SwissProt Accessions	O95196, Q71M39, Q71M40	Gene names	CSPG5, CALEB, NGC
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

FOXN1_HUMAN
NC score	0.070094 (rank : 543)	θ value	0.47712 (rank : 411)
Query Neighborhood Hits	872	Target Neighborhood Hits	377	Shared Neighborhood Hits	182
SwissProt Accessions	O15353, O15352	Gene names	FOXN1, WHN
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude).

CJ078_MOUSE
NC score	0.070061 (rank : 544)	θ value	θ > 10 (rank : 926)
Query Neighborhood Hits	872	Target Neighborhood Hits	559	Shared Neighborhood Hits	118
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

SYNPO_MOUSE
NC score	0.069573 (rank : 545)	θ value	0.813845 (rank : 479)
Query Neighborhood Hits	872	Target Neighborhood Hits	242	Shared Neighborhood Hits	84
SwissProt Accessions	Q8CC35, Q99JI0	Gene names	Synpo, Kiaa1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

FGD3_HUMAN
NC score	0.069483 (rank : 546)	θ value	θ > 10 (rank : 990)
Query Neighborhood Hits	872	Target Neighborhood Hits	249	Shared Neighborhood Hits	61
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

FGD3_MOUSE
NC score	0.069380 (rank : 547)	θ value	θ > 10 (rank : 991)
Query Neighborhood Hits	872	Target Neighborhood Hits	257	Shared Neighborhood Hits	51
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

PER2_MOUSE
NC score	0.069356 (rank : 548)	θ value	θ > 10 (rank : 1067)
Query Neighborhood Hits	872	Target Neighborhood Hits	325	Shared Neighborhood Hits	136
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

ARMX2_MOUSE
NC score	0.069334 (rank : 549)	θ value	θ > 10 (rank : 896)
Query Neighborhood Hits	872	Target Neighborhood Hits	349	Shared Neighborhood Hits	164
SwissProt Accessions	Q6A058, Q9CXI9	Gene names	Armcx2, Kiaa0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2.

CONA1_MOUSE
NC score	0.069132 (rank : 550)	θ value	θ > 10 (rank : 950)
Query Neighborhood Hits	872	Target Neighborhood Hits	254	Shared Neighborhood Hits	96
SwissProt Accessions	Q8K4G2, Q5SUQ0	Gene names	Col23a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

MEGF9_MOUSE
NC score	0.069071 (rank : 551)	θ value	1.38821 (rank : 538)
Query Neighborhood Hits	872	Target Neighborhood Hits	896	Shared Neighborhood Hits	229
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

EPN3_HUMAN
NC score	0.069044 (rank : 552)	θ value	θ > 10 (rank : 977)
Query Neighborhood Hits	872	Target Neighborhood Hits	197	Shared Neighborhood Hits	86
SwissProt Accessions	Q9H201, Q9BVN6, Q9NWK2	Gene names	EPN3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

SPN90_HUMAN
NC score	0.068904 (rank : 553)	θ value	θ > 10 (rank : 1111)
Query Neighborhood Hits	872	Target Neighborhood Hits	157	Shared Neighborhood Hits	70
SwissProt Accessions	Q9NZQ3, Q9UGM8	Gene names	NCKIPSD, AF3P21, SPIN90
Domain Architecture
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (AF3p21) (Diaphanous protein-interacting protein) (Dia-interacting protein 1) (DIP-1).

ARHG1_MOUSE
NC score	0.068797 (rank : 554)	θ value	θ > 10 (rank : 881)
Query Neighborhood Hits	872	Target Neighborhood Hits	266	Shared Neighborhood Hits	107
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

BRD4_MOUSE
NC score	0.068754 (rank : 555)	θ value	0.813845 (rank : 450)
Query Neighborhood Hits	872	Target Neighborhood Hits	845	Shared Neighborhood Hits	155
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

RIMB1_MOUSE
NC score	0.068730 (rank : 556)	θ value	3.0926 (rank : 660)
Query Neighborhood Hits	872	Target Neighborhood Hits	1376	Shared Neighborhood Hits	231
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

CRSP7_HUMAN
NC score	0.068626 (rank : 557)	θ value	θ > 10 (rank : 954)
Query Neighborhood Hits	872	Target Neighborhood Hits	247	Shared Neighborhood Hits	119
SwissProt Accessions	O95402	Gene names	CRSP7, ARC70
Domain Architecture
Description	CRSP complex subunit 7 (Cofactor required for Sp1 transcriptional activation subunit 7) (Transcriptional coactivator CRSP70) (Activator- recruited cofactor 70 kDa component) (ARC70).

ANK2_HUMAN
NC score	0.068587 (rank : 558)	θ value	θ > 10 (rank : 875)
Query Neighborhood Hits	872	Target Neighborhood Hits	1615	Shared Neighborhood Hits	300
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

SPTA2_HUMAN
NC score	0.068480 (rank : 559)	θ value	θ > 10 (rank : 1118)
Query Neighborhood Hits	872	Target Neighborhood Hits	888	Shared Neighborhood Hits	133
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

CO9A2_HUMAN
NC score	0.068261 (rank : 560)	θ value	θ > 10 (rank : 943)
Query Neighborhood Hits	872	Target Neighborhood Hits	261	Shared Neighborhood Hits	97
SwissProt Accessions	Q14055	Gene names	COL9A2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(IX) chain precursor.

PAF49_HUMAN
NC score	0.068046 (rank : 561)	θ value	0.0252991 (rank : 241)
Query Neighborhood Hits	872	Target Neighborhood Hits	169	Shared Neighborhood Hits	38
SwissProt Accessions	O15446, Q32N11, Q7Z5U2, Q9UPF6	Gene names	CD3EAP, ASE1, CAST, PAF49
Domain Architecture	No domain graphic available
Description	RNA polymerase I-associated factor PAF49 (Anti-sense to ERCC-1 protein) (ASE-1) (CD3-epsilon-associated protein) (CD3E-associated protein) (CAST).

ATX1_MOUSE
NC score	0.068010 (rank : 562)	θ value	θ > 10 (rank : 897)
Query Neighborhood Hits	872	Target Neighborhood Hits	264	Shared Neighborhood Hits	112
SwissProt Accessions	P54254	Gene names	Atxn1, Sca1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).

SOS1_HUMAN
NC score	0.067990 (rank : 563)	θ value	0.0563607 (rank : 284)
Query Neighborhood Hits	872	Target Neighborhood Hits	274	Shared Neighborhood Hits	79
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

RBM16_HUMAN
NC score	0.067876 (rank : 564)	θ value	2.36792 (rank : 615)
Query Neighborhood Hits	872	Target Neighborhood Hits	300	Shared Neighborhood Hits	98
SwissProt Accessions	Q9UPN6, Q5TBU6, Q9BQN8, Q9BX43	Gene names	RBM16, KIAA1116
Domain Architecture
Description	Putative RNA-binding protein 16 (RNA-binding motif protein 16).

MAML3_HUMAN
NC score	0.067651 (rank : 565)	θ value	θ > 10 (rank : 1031)
Query Neighborhood Hits	872	Target Neighborhood Hits	323	Shared Neighborhood Hits	112
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

FGD4_MOUSE
NC score	0.067638 (rank : 566)	θ value	θ > 10 (rank : 993)
Query Neighborhood Hits	872	Target Neighborhood Hits	227	Shared Neighborhood Hits	41
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

HRBL_HUMAN
NC score	0.067362 (rank : 567)	θ value	θ > 10 (rank : 1013)
Query Neighborhood Hits	872	Target Neighborhood Hits	179	Shared Neighborhood Hits	85
SwissProt Accessions	O95081, O75429, Q96AB9, Q96GL4	Gene names	HRBL, RABR
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

BRD4_HUMAN
NC score	0.067254 (rank : 568)	θ value	0.279714 (rank : 372)
Query Neighborhood Hits	872	Target Neighborhood Hits	851	Shared Neighborhood Hits	160
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

HAIR_HUMAN
NC score	0.067080 (rank : 569)	θ value	0.0148317 (rank : 210)
Query Neighborhood Hits	872	Target Neighborhood Hits	172	Shared Neighborhood Hits	73
SwissProt Accessions	O43593, Q96H33, Q9NPE1	Gene names	HR
Domain Architecture
Description	Protein hairless.

FHOD1_HUMAN
NC score	0.066893 (rank : 570)	θ value	1.38821 (rank : 534)
Query Neighborhood Hits	872	Target Neighborhood Hits	184	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y613, Q59F76, Q6Y1F2, Q76MS8, Q8N521	Gene names	FHOD1, FHOS
Domain Architecture
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

CIP4_HUMAN
NC score	0.066771 (rank : 571)	θ value	θ > 10 (rank : 924)
Query Neighborhood Hits	872	Target Neighborhood Hits	374	Shared Neighborhood Hits	49
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

DDFL1_MOUSE
NC score	0.066769 (rank : 572)	θ value	θ > 10 (rank : 967)
Query Neighborhood Hits	872	Target Neighborhood Hits	324	Shared Neighborhood Hits	37
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

RU1C_MOUSE
NC score	0.066717 (rank : 573)	θ value	1.06291 (rank : 508)
Query Neighborhood Hits	872	Target Neighborhood Hits	83	Shared Neighborhood Hits	38
SwissProt Accessions	Q62241	Gene names	Snrp1c, Snrpc
Domain Architecture
Description	U1 small nuclear ribonucleoprotein C (U1 snRNP protein C) (U1C protein) (U1-C).

MCF2L_MOUSE
NC score	0.066629 (rank : 574)	θ value	θ > 10 (rank : 1038)
Query Neighborhood Hits	872	Target Neighborhood Hits	255	Shared Neighborhood Hits	49
SwissProt Accessions	Q64096	Gene names	Mcf2l, Dbs
Domain Architecture
Description	Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2- transforming sequence-like protein).

FGD4_HUMAN
NC score	0.066399 (rank : 575)	θ value	θ > 10 (rank : 992)
Query Neighborhood Hits	872	Target Neighborhood Hits	219	Shared Neighborhood Hits	40
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

CJ047_HUMAN
NC score	0.066282 (rank : 576)	θ value	0.279714 (rank : 373)
Query Neighborhood Hits	872	Target Neighborhood Hits	164	Shared Neighborhood Hits	67
SwissProt Accessions	Q86WR7, Q5W0J9, Q5W0K0, Q5W0K1, Q5W0K2, Q6PJC8, Q8N317	Gene names	C10orf47
Domain Architecture	No domain graphic available
Description	Protein C10orf47.

SASH1_HUMAN
NC score	0.066123 (rank : 577)	θ value	4.03905 (rank : 694)
Query Neighborhood Hits	872	Target Neighborhood Hits	292	Shared Neighborhood Hits	137
SwissProt Accessions	O94885, Q8TAI0, Q9H7R7	Gene names	SASH1, KIAA0790, PEPE1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat- containing protein).

PP1RA_HUMAN
NC score	0.065856 (rank : 578)	θ value	0.62314 (rank : 444)
Query Neighborhood Hits	872	Target Neighborhood Hits	180	Shared Neighborhood Hits	74
SwissProt Accessions	Q96QC0, O00405	Gene names	PPP1R10, CAT53, FB19, PNUTS
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 1 regulatory subunit 10 (Phosphatase 1 nuclear targeting subunit) (MHC class I region proline- rich protein CAT53) (FB19 protein) (PP1-binding protein of 114 kDa) (p99).

CPSF7_HUMAN
NC score	0.065801 (rank : 579)	θ value	2.36792 (rank : 591)
Query Neighborhood Hits	872	Target Neighborhood Hits	125	Shared Neighborhood Hits	43
SwissProt Accessions	Q8N684, Q7Z3H9, Q9H025, Q9H9V1	Gene names	CPSF7
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 7 (Cleavage and polyadenylation specificity factor 59 kDa subunit) (CPSF 59 kDa subunit) (Pre-mRNA cleavage factor Im 59 kDa subunit).

CPSF7_MOUSE
NC score	0.065784 (rank : 580)	θ value	2.36792 (rank : 592)
Query Neighborhood Hits	872	Target Neighborhood Hits	123	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BTV2, Q3TNF1, Q8BKE7, Q8CFS8	Gene names	Cpsf7
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 7.

PELP1_HUMAN
NC score	0.065760 (rank : 581)	θ value	2.36792 (rank : 610)
Query Neighborhood Hits	872	Target Neighborhood Hits	596	Shared Neighborhood Hits	115
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

ALO17_HUMAN
NC score	0.065751 (rank : 582)	θ value	0.0961366 (rank : 303)
Query Neighborhood Hits	872	Target Neighborhood Hits	317	Shared Neighborhood Hits	48
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

PO121_HUMAN
NC score	0.065545 (rank : 583)	θ value	2.36792 (rank : 614)
Query Neighborhood Hits	872	Target Neighborhood Hits	344	Shared Neighborhood Hits	86
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

RGNEF_MOUSE
NC score	0.065527 (rank : 584)	θ value	θ > 10 (rank : 1083)
Query Neighborhood Hits	872	Target Neighborhood Hits	641	Shared Neighborhood Hits	69
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

CG1_HUMAN
NC score	0.065438 (rank : 585)	θ value	2.36792 (rank : 588)
Query Neighborhood Hits	872	Target Neighborhood Hits	222	Shared Neighborhood Hits	91
SwissProt Accessions	Q13495	Gene names	CXorf6, CG1
Domain Architecture	No domain graphic available
Description	CG1 protein (F18).

CD248_MOUSE
NC score	0.065437 (rank : 586)	θ value	θ > 10 (rank : 911)
Query Neighborhood Hits	872	Target Neighborhood Hits	578	Shared Neighborhood Hits	175
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

BLNK_MOUSE
NC score	0.065363 (rank : 587)	θ value	θ > 10 (rank : 905)
Query Neighborhood Hits	872	Target Neighborhood Hits	296	Shared Neighborhood Hits	107
SwissProt Accessions	Q9QUN3, O88504	Gene names	Blnk, Bash, Ly57, Slp65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65) (Lymphocyte antigen 57).

LSD1_HUMAN
NC score	0.065068 (rank : 588)	θ value	8.99809 (rank : 840)
Query Neighborhood Hits	872	Target Neighborhood Hits	455	Shared Neighborhood Hits	149
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

SOS1_MOUSE
NC score	0.064804 (rank : 589)	θ value	0.125558 (rank : 325)
Query Neighborhood Hits	872	Target Neighborhood Hits	281	Shared Neighborhood Hits	75
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

R3HD1_HUMAN
NC score	0.064767 (rank : 590)	θ value	0.0563607 (rank : 282)
Query Neighborhood Hits	872	Target Neighborhood Hits	203	Shared Neighborhood Hits	66
SwissProt Accessions	Q15032, Q8IW32	Gene names	R3HDM1, KIAA0029, R3HDM
Domain Architecture	No domain graphic available
Description	R3H domain-containing protein 1.

CO039_HUMAN
NC score	0.064612 (rank : 591)	θ value	θ > 10 (rank : 932)
Query Neighborhood Hits	872	Target Neighborhood Hits	264	Shared Neighborhood Hits	108
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

VASP_HUMAN
NC score	0.064598 (rank : 592)	θ value	8.99809 (rank : 869)
Query Neighborhood Hits	872	Target Neighborhood Hits	201	Shared Neighborhood Hits	81
SwissProt Accessions	P50552, Q6PIZ1, Q93035	Gene names	VASP
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

TS13_MOUSE
NC score	0.064539 (rank : 593)	θ value	θ > 10 (rank : 1135)
Query Neighborhood Hits	872	Target Neighborhood Hits	191	Shared Neighborhood Hits	85
SwissProt Accessions	Q01755	Gene names	Tcp11
Domain Architecture
Description	Testis-specific protein PBS13.

APXL_HUMAN
NC score	0.064538 (rank : 594)	θ value	8.99809 (rank : 803)
Query Neighborhood Hits	872	Target Neighborhood Hits	553	Shared Neighborhood Hits	132
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

CITE4_HUMAN
NC score	0.064506 (rank : 595)	θ value	1.81305 (rank : 559)
Query Neighborhood Hits	872	Target Neighborhood Hits	67	Shared Neighborhood Hits	33
SwissProt Accessions	Q96RK1	Gene names	CITED4, MRG2
Domain Architecture	No domain graphic available
Description	Cbp/p300-interacting transactivator 4 (MSG1-related protein 2) (MRG- 2).

SYNPO_HUMAN
NC score	0.064429 (rank : 596)	θ value	θ > 10 (rank : 1122)
Query Neighborhood Hits	872	Target Neighborhood Hits	281	Shared Neighborhood Hits	107
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

MAVS_HUMAN
NC score	0.064199 (rank : 597)	θ value	6.88961 (rank : 782)
Query Neighborhood Hits	872	Target Neighborhood Hits	271	Shared Neighborhood Hits	97
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

NU214_HUMAN
NC score	0.063971 (rank : 598)	θ value	θ > 10 (rank : 1057)
Query Neighborhood Hits	872	Target Neighborhood Hits	657	Shared Neighborhood Hits	138
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

ENAH_HUMAN
NC score	0.063967 (rank : 599)	θ value	0.47712 (rank : 406)
Query Neighborhood Hits	872	Target Neighborhood Hits	784	Shared Neighborhood Hits	130
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

PRPC_HUMAN
NC score	0.063824 (rank : 600)	θ value	θ > 10 (rank : 1080)
Query Neighborhood Hits	872	Target Neighborhood Hits	165	Shared Neighborhood Hits	54
SwissProt Accessions	P02810, Q4VBP2, Q53XA2, Q6P2F6	Gene names	PRH1
Domain Architecture	No domain graphic available
Description	Salivary acidic proline-rich phosphoprotein 1/2 precursor (PRP-1/PRP- 2) (Parotid proline-rich protein 1/2) (Pr1/Pr2) (Protein C) (Parotid acidic protein) (Pa) (Parotid isoelectric focusing variant protein) (PIF-S) (Parotid double-band protein) (Db-s) [Contains: Salivary acidic proline-rich phosphoprotein 1/2; Salivary acidic proline-rich phosphoprotein 3/4 (PRP-3/PRP-4) (Protein A) (PIF-F) (Db-F); Peptide P-C].

DOK7_MOUSE
NC score	0.063575 (rank : 601)	θ value	8.99809 (rank : 819)
Query Neighborhood Hits	872	Target Neighborhood Hits	169	Shared Neighborhood Hits	82
SwissProt Accessions	Q18PE0, Q3TCZ6, Q5FW70, Q8C8U7	Gene names	Dok7
Domain Architecture	No domain graphic available
Description	Protein Dok-7 (Downstream of tyrosine kinase 7).

FGD2_HUMAN
NC score	0.063553 (rank : 602)	θ value	θ > 10 (rank : 988)
Query Neighborhood Hits	872	Target Neighborhood Hits	151	Shared Neighborhood Hits	31
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

INP5E_HUMAN
NC score	0.063403 (rank : 603)	θ value	θ > 10 (rank : 1017)
Query Neighborhood Hits	872	Target Neighborhood Hits	201	Shared Neighborhood Hits	102
SwissProt Accessions	Q9NRR6, Q15734	Gene names	INPP5E
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

SYNP2_HUMAN
NC score	0.063282 (rank : 604)	θ value	5.27518 (rank : 742)
Query Neighborhood Hits	872	Target Neighborhood Hits	323	Shared Neighborhood Hits	107
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

EMID1_MOUSE
NC score	0.063076 (rank : 605)	θ value	θ > 10 (rank : 974)
Query Neighborhood Hits	872	Target Neighborhood Hits	230	Shared Neighborhood Hits	89
SwissProt Accessions	Q91VF5	Gene names	Emid1, Emu1
Domain Architecture	No domain graphic available
Description	EMI domain-containing protein 1 precursor (Protein Emu1) (Emilin and multimerin domain-containing protein 1).

ES8L3_MOUSE
NC score	0.062938 (rank : 606)	θ value	θ > 10 (rank : 981)
Query Neighborhood Hits	872	Target Neighborhood Hits	168	Shared Neighborhood Hits	88
SwissProt Accessions	Q91WL0, Q3TJ14	Gene names	Eps8l3, Eps8r3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor pathway substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

PDC6I_HUMAN
NC score	0.062854 (rank : 607)	θ value	1.38821 (rank : 541)
Query Neighborhood Hits	872	Target Neighborhood Hits	278	Shared Neighborhood Hits	83
SwissProt Accessions	Q8WUM4, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5	Gene names	PDCD6IP, AIP1, ALIX, KIAA1375
Domain Architecture
Description	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95).

VASP_MOUSE
NC score	0.062805 (rank : 608)	θ value	1.06291 (rank : 520)
Query Neighborhood Hits	872	Target Neighborhood Hits	195	Shared Neighborhood Hits	66
SwissProt Accessions	P70460, Q3TAP0, Q3TCD2, Q3U0C2, Q3UDF1, Q91VD2, Q9R214	Gene names	Vasp
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

DIAP2_MOUSE
NC score	0.062699 (rank : 609)	θ value	5.27518 (rank : 712)
Query Neighborhood Hits	872	Target Neighborhood Hits	260	Shared Neighborhood Hits	67
SwissProt Accessions	O70566, Q8C2G8	Gene names	Diaph2, Diap2
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2) (mDia3).

IRS2_MOUSE
NC score	0.062653 (rank : 610)	θ value	0.47712 (rank : 412)
Query Neighborhood Hits	872	Target Neighborhood Hits	248	Shared Neighborhood Hits	84
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

PCQAP_MOUSE
NC score	0.062627 (rank : 611)	θ value	θ > 10 (rank : 1064)
Query Neighborhood Hits	872	Target Neighborhood Hits	506	Shared Neighborhood Hits	103
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

ARHG1_HUMAN
NC score	0.062562 (rank : 612)	θ value	θ > 10 (rank : 880)
Query Neighborhood Hits	872	Target Neighborhood Hits	176	Shared Neighborhood Hits	70
SwissProt Accessions	Q92888, O00513, Q8N4J4, Q96BF4, Q96F17, Q9BSB1	Gene names	ARHGEF1
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide exchange factor) (Sub1.5).

SSBP3_HUMAN
NC score	0.062497 (rank : 613)	θ value	1.06291 (rank : 515)
Query Neighborhood Hits	872	Target Neighborhood Hits	132	Shared Neighborhood Hits	75
SwissProt Accessions	Q9BWW4, Q9BTM0, Q9BWW3	Gene names	SSBP3, SSDP, SSDP1
Domain Architecture
Description	Single-stranded DNA-binding protein 3 (Sequence-specific single- stranded-DNA-binding protein).

SSBP3_MOUSE
NC score	0.062497 (rank : 614)	θ value	1.06291 (rank : 516)
Query Neighborhood Hits	872	Target Neighborhood Hits	132	Shared Neighborhood Hits	75
SwissProt Accessions	Q9D032, Q99LC6, Q9EQP3	Gene names	Ssbp3, Last, Ssdp1
Domain Architecture
Description	Single-stranded DNA-binding protein 3 (Sequence-specific single- stranded-DNA-binding protein) (Lck-associated signal transducer).

PKHA4_HUMAN
NC score	0.062492 (rank : 615)	θ value	1.06291 (rank : 506)
Query Neighborhood Hits	872	Target Neighborhood Hits	283	Shared Neighborhood Hits	79
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

SYNG_MOUSE
NC score	0.062467 (rank : 616)	θ value	1.06291 (rank : 517)
Query Neighborhood Hits	872	Target Neighborhood Hits	206	Shared Neighborhood Hits	86
SwissProt Accessions	Q5SV85, Q5SV84, Q6PHT6	Gene names	Ap1gbp1, Syng
Domain Architecture	No domain graphic available
Description	AP1 subunit gamma-binding protein 1 (Gamma-synergin).

AB1IP_MOUSE
NC score	0.062419 (rank : 617)	θ value	1.81305 (rank : 554)
Query Neighborhood Hits	872	Target Neighborhood Hits	181	Shared Neighborhood Hits	58
SwissProt Accessions	Q8R5A3, O35329, Q8BRU0, Q99KV8	Gene names	Apbb1ip, Prel1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 48).

JIP1_HUMAN
NC score	0.062266 (rank : 618)	θ value	θ > 10 (rank : 1019)
Query Neighborhood Hits	872	Target Neighborhood Hits	271	Shared Neighborhood Hits	121
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

AMPH_MOUSE
NC score	0.062179 (rank : 619)	θ value	θ > 10 (rank : 874)
Query Neighborhood Hits	872	Target Neighborhood Hits	291	Shared Neighborhood Hits	90
SwissProt Accessions	Q7TQF7, Q8R1C4	Gene names	Amph, Amph1
Domain Architecture
Description	Amphiphysin.

SOX13_MOUSE
NC score	0.062144 (rank : 620)	θ value	θ > 10 (rank : 1109)
Query Neighborhood Hits	872	Target Neighborhood Hits	495	Shared Neighborhood Hits	167
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

DAB1_HUMAN
NC score	0.062042 (rank : 621)	θ value	θ > 10 (rank : 959)
Query Neighborhood Hits	872	Target Neighborhood Hits	219	Shared Neighborhood Hits	95
SwissProt Accessions	O75553, Q9NYA8	Gene names	DAB1
Domain Architecture
Description	Disabled homolog 1.

PKHG4_HUMAN
NC score	0.061662 (rank : 622)	θ value	θ > 10 (rank : 1073)
Query Neighborhood Hits	872	Target Neighborhood Hits	200	Shared Neighborhood Hits	84
SwissProt Accessions	Q58EX7, Q4G0J8, Q4H485, Q56A69, Q9H7K4, Q9UFW0	Gene names	PLEKHG4, PRTPHN1
Domain Architecture	No domain graphic available
Description	Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1).

DIAP2_HUMAN
NC score	0.061536 (rank : 623)	θ value	6.88961 (rank : 766)
Query Neighborhood Hits	872	Target Neighborhood Hits	342	Shared Neighborhood Hits	70
SwissProt Accessions	O60879, O60878, Q8WX06, Q8WX48, Q9UJL2	Gene names	DIAPH2, DIA
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2).

ZN750_MOUSE
NC score	0.061290 (rank : 624)	θ value	θ > 10 (rank : 1142)
Query Neighborhood Hits	872	Target Neighborhood Hits	346	Shared Neighborhood Hits	105
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

JIP1_MOUSE
NC score	0.061181 (rank : 625)	θ value	θ > 10 (rank : 1020)
Query Neighborhood Hits	872	Target Neighborhood Hits	259	Shared Neighborhood Hits	116
SwissProt Accessions	Q9WVI9, O35145, Q925J8, Q9R1H9, Q9R1Z1, Q9WVI7, Q9WVI8	Gene names	Mapk8ip1, Ib1, Jip1, Mapk8ip, Prkm8ip
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain-1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

RU1C_HUMAN
NC score	0.061139 (rank : 626)	θ value	2.36792 (rank : 616)
Query Neighborhood Hits	872	Target Neighborhood Hits	81	Shared Neighborhood Hits	37
SwissProt Accessions	P09234	Gene names	SNRPC
Domain Architecture
Description	U1 small nuclear ribonucleoprotein C (U1 snRNP protein C) (U1C protein) (U1-C).

ZN409_HUMAN
NC score	0.061024 (rank : 627)	θ value	0.813845 (rank : 482)
Query Neighborhood Hits	872	Target Neighborhood Hits	842	Shared Neighborhood Hits	148
SwissProt Accessions	Q9UPU6	Gene names	ZNF409, KIAA1056
Domain Architecture	No domain graphic available
Description	Zinc finger protein 409.

PDC6I_MOUSE
NC score	0.061000 (rank : 628)	θ value	4.03905 (rank : 690)
Query Neighborhood Hits	872	Target Neighborhood Hits	275	Shared Neighborhood Hits	87
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

PTN23_MOUSE
NC score	0.060996 (rank : 629)	θ value	0.0330416 (rank : 254)
Query Neighborhood Hits	872	Target Neighborhood Hits	726	Shared Neighborhood Hits	183
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

MUC2_HUMAN
NC score	0.060845 (rank : 630)	θ value	0.47712 (rank : 415)
Query Neighborhood Hits	872	Target Neighborhood Hits	906	Shared Neighborhood Hits	154
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

FGD6_MOUSE
NC score	0.060838 (rank : 631)	θ value	θ > 10 (rank : 995)
Query Neighborhood Hits	872	Target Neighborhood Hits	282	Shared Neighborhood Hits	57
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

GAB1_HUMAN
NC score	0.060792 (rank : 632)	θ value	θ > 10 (rank : 997)
Query Neighborhood Hits	872	Target Neighborhood Hits	279	Shared Neighborhood Hits	120
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

SPTA1_MOUSE
NC score	0.060737 (rank : 633)	θ value	θ > 10 (rank : 1117)
Query Neighborhood Hits	872	Target Neighborhood Hits	675	Shared Neighborhood Hits	124
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

IWS1_MOUSE
NC score	0.060618 (rank : 634)	θ value	8.99809 (rank : 833)
Query Neighborhood Hits	872	Target Neighborhood Hits	1258	Shared Neighborhood Hits	183
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

BAG3_HUMAN
NC score	0.060492 (rank : 635)	θ value	θ > 10 (rank : 900)
Query Neighborhood Hits	872	Target Neighborhood Hits	314	Shared Neighborhood Hits	117
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

CS007_MOUSE
NC score	0.060483 (rank : 636)	θ value	θ > 10 (rank : 955)
Query Neighborhood Hits	872	Target Neighborhood Hits	464	Shared Neighborhood Hits	150
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

COEA1_HUMAN
NC score	0.060459 (rank : 637)	θ value	0.00509761 (rank : 169)
Query Neighborhood Hits	872	Target Neighborhood Hits	427	Shared Neighborhood Hits	103
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

PDZD8_HUMAN
NC score	0.060271 (rank : 638)	θ value	θ > 10 (rank : 1066)
Query Neighborhood Hits	872	Target Neighborhood Hits	185	Shared Neighborhood Hits	31
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

GRIN1_MOUSE
NC score	0.060161 (rank : 639)	θ value	θ > 10 (rank : 1009)
Query Neighborhood Hits	872	Target Neighborhood Hits	337	Shared Neighborhood Hits	91
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

RBM12_HUMAN
NC score	0.060128 (rank : 640)	θ value	1.38821 (rank : 544)
Query Neighborhood Hits	872	Target Neighborhood Hits	298	Shared Neighborhood Hits	91
SwissProt Accessions	Q9NTZ6, O94865, Q8N3B1, Q9H196	Gene names	RBM12, KIAA0765
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

HGS_MOUSE
NC score	0.060066 (rank : 641)	θ value	θ > 10 (rank : 1012)
Query Neighborhood Hits	872	Target Neighborhood Hits	589	Shared Neighborhood Hits	139
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

PCX3_MOUSE
NC score	0.060036 (rank : 642)	θ value	0.00298849 (rank : 154)
Query Neighborhood Hits	872	Target Neighborhood Hits	134	Shared Neighborhood Hits	49
SwissProt Accessions	Q8VI59	Gene names	Pcnxl3
Domain Architecture
Description	Pecanex-like protein 3.

FGD2_MOUSE
NC score	0.060017 (rank : 643)	θ value	θ > 10 (rank : 989)
Query Neighborhood Hits	872	Target Neighborhood Hits	163	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

SMR1_MOUSE
NC score	0.059996 (rank : 644)	θ value	2.36792 (rank : 620)
Query Neighborhood Hits	872	Target Neighborhood Hits	103	Shared Neighborhood Hits	50
SwissProt Accessions	Q61900	Gene names	Smr1, Msg1
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 1 precursor (Salivary protein MSG1).

SMAP1_MOUSE
NC score	0.059903 (rank : 645)	θ value	θ > 10 (rank : 1099)
Query Neighborhood Hits	872	Target Neighborhood Hits	120	Shared Neighborhood Hits	36
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

EPN2_HUMAN
NC score	0.059587 (rank : 646)	θ value	1.38821 (rank : 533)
Query Neighborhood Hits	872	Target Neighborhood Hits	156	Shared Neighborhood Hits	55
SwissProt Accessions	O95208, O95207, Q9H7Z2, Q9UPT7	Gene names	EPN2, KIAA1065
Domain Architecture
Description	Epsin-2 (EPS-15-interacting protein 2).

LARP4_MOUSE
NC score	0.059577 (rank : 647)	θ value	5.27518 (rank : 726)
Query Neighborhood Hits	872	Target Neighborhood Hits	260	Shared Neighborhood Hits	106
SwissProt Accessions	Q8BWW4, Q3UR69	Gene names	Larp4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

SF3B1_HUMAN
NC score	0.059528 (rank : 648)	θ value	θ > 10 (rank : 1092)
Query Neighborhood Hits	872	Target Neighborhood Hits	341	Shared Neighborhood Hits	117
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SSXT_MOUSE
NC score	0.059491 (rank : 649)	θ value	0.0736092 (rank : 299)
Query Neighborhood Hits	872	Target Neighborhood Hits	118	Shared Neighborhood Hits	46
SwissProt Accessions	Q62280	Gene names	Ss18, Ssxt, Syt
Domain Architecture
Description	SSXT protein (SYT protein) (Synovial sarcoma-associated Ss18-alpha).

UN13A_HUMAN
NC score	0.059476 (rank : 650)	θ value	θ > 10 (rank : 1138)
Query Neighborhood Hits	872	Target Neighborhood Hits	285	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

CP007_MOUSE
NC score	0.059315 (rank : 651)	θ value	2.36792 (rank : 590)
Query Neighborhood Hits	872	Target Neighborhood Hits	231	Shared Neighborhood Hits	76
SwissProt Accessions	Q8C190, Q6PFD1	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf7 homolog (5-day ovary-specific transcript 1 protein).

ARHGB_HUMAN
NC score	0.059311 (rank : 652)	θ value	θ > 10 (rank : 891)
Query Neighborhood Hits	872	Target Neighborhood Hits	375	Shared Neighborhood Hits	66
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

SF3B1_MOUSE
NC score	0.059279 (rank : 653)	θ value	θ > 10 (rank : 1093)
Query Neighborhood Hits	872	Target Neighborhood Hits	352	Shared Neighborhood Hits	118
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

HCN4_HUMAN
NC score	0.059169 (rank : 654)	θ value	5.44631e-05 (rank : 85)
Query Neighborhood Hits	872	Target Neighborhood Hits	303	Shared Neighborhood Hits	101
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

SSXT_HUMAN
NC score	0.059094 (rank : 655)	θ value	0.125558 (rank : 326)
Query Neighborhood Hits	872	Target Neighborhood Hits	125	Shared Neighborhood Hits	48
SwissProt Accessions	Q15532, Q16404, Q9BXC6	Gene names	SS18, SSXT, SYT
Domain Architecture
Description	SSXT protein (Synovial sarcoma, translocated to X chromosome) (SYT protein).

SNX22_HUMAN
NC score	0.058925 (rank : 656)	θ value	0.125558 (rank : 324)
Query Neighborhood Hits	872	Target Neighborhood Hits	31	Shared Neighborhood Hits	6
SwissProt Accessions	Q96L94, Q9H844	Gene names	SNX22
Domain Architecture
Description	Sorting nexin-22.

SHLB2_HUMAN
NC score	0.058895 (rank : 657)	θ value	θ > 10 (rank : 1096)
Query Neighborhood Hits	872	Target Neighborhood Hits	86	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NR46, Q8WY61, Q96JH9	Gene names	SH3GLB2, KIAA1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

MINT_HUMAN
NC score	0.058859 (rank : 658)	θ value	6.88961 (rank : 783)
Query Neighborhood Hits	872	Target Neighborhood Hits	1291	Shared Neighborhood Hits	193
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

SMP1L_HUMAN
NC score	0.058843 (rank : 659)	θ value	θ > 10 (rank : 1101)
Query Neighborhood Hits	872	Target Neighborhood Hits	74	Shared Neighborhood Hits	23
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

SOX30_MOUSE
NC score	0.058843 (rank : 660)	θ value	θ > 10 (rank : 1110)
Query Neighborhood Hits	872	Target Neighborhood Hits	374	Shared Neighborhood Hits	165
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

SHLB2_MOUSE
NC score	0.058830 (rank : 661)	θ value	θ > 10 (rank : 1097)
Query Neighborhood Hits	872	Target Neighborhood Hits	88	Shared Neighborhood Hits	52
SwissProt Accessions	Q8R3V5, Q8K140, Q91ZI7	Gene names	Sh3glb2, Kiaa1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

BASP_MOUSE
NC score	0.058818 (rank : 662)	θ value	θ > 10 (rank : 902)
Query Neighborhood Hits	872	Target Neighborhood Hits	260	Shared Neighborhood Hits	56
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

JIP2_HUMAN
NC score	0.058592 (rank : 663)	θ value	θ > 10 (rank : 1021)
Query Neighborhood Hits	872	Target Neighborhood Hits	288	Shared Neighborhood Hits	137
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

PDCD7_MOUSE
NC score	0.058557 (rank : 664)	θ value	0.47712 (rank : 416)
Query Neighborhood Hits	872	Target Neighborhood Hits	214	Shared Neighborhood Hits	44
SwissProt Accessions	Q9WTY1, Q8R5D9	Gene names	Pdcd7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18).

SASH1_MOUSE
NC score	0.058487 (rank : 665)	θ value	θ > 10 (rank : 1089)
Query Neighborhood Hits	872	Target Neighborhood Hits	263	Shared Neighborhood Hits	102
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

SMAP1_HUMAN
NC score	0.058477 (rank : 666)	θ value	θ > 10 (rank : 1098)
Query Neighborhood Hits	872	Target Neighborhood Hits	98	Shared Neighborhood Hits	28
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

HCN2_HUMAN
NC score	0.058437 (rank : 667)	θ value	3.0926 (rank : 647)
Query Neighborhood Hits	872	Target Neighborhood Hits	369	Shared Neighborhood Hits	141
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

MBD5_HUMAN
NC score	0.058397 (rank : 668)	θ value	1.06291 (rank : 502)
Query Neighborhood Hits	872	Target Neighborhood Hits	176	Shared Neighborhood Hits	55
SwissProt Accessions	Q9P267, Q9NUV6	Gene names	MBD5, KIAA1461
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 5 (Methyl-CpG-binding protein MBD5).

DAAM1_HUMAN
NC score	0.058237 (rank : 669)	θ value	0.62314 (rank : 430)
Query Neighborhood Hits	872	Target Neighborhood Hits	483	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y4D1, Q86U34, Q8N1Z8, Q8TB39	Gene names	DAAM1, KIAA0666
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

SPTA1_HUMAN
NC score	0.058156 (rank : 670)	θ value	θ > 10 (rank : 1116)
Query Neighborhood Hits	872	Target Neighborhood Hits	748	Shared Neighborhood Hits	129
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

MAML1_MOUSE
NC score	0.058118 (rank : 671)	θ value	θ > 10 (rank : 1030)
Query Neighborhood Hits	872	Target Neighborhood Hits	279	Shared Neighborhood Hits	113
SwissProt Accessions	Q6T264, Q505D8, Q5SUC2, Q6PDK3, Q6ZQG5, Q8BIU5, Q8R3T0	Gene names	Maml1, Kiaa0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

SMP1L_MOUSE
NC score	0.058023 (rank : 672)	θ value	θ > 10 (rank : 1102)
Query Neighborhood Hits	872	Target Neighborhood Hits	70	Shared Neighborhood Hits	20
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

BAZ2A_HUMAN
NC score	0.057975 (rank : 673)	θ value	θ > 10 (rank : 904)
Query Neighborhood Hits	872	Target Neighborhood Hits	780	Shared Neighborhood Hits	176
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

CGRE1_HUMAN
NC score	0.057825 (rank : 674)	θ value	θ > 10 (rank : 923)
Query Neighborhood Hits	872	Target Neighborhood Hits	354	Shared Neighborhood Hits	90
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

SPN90_MOUSE
NC score	0.057626 (rank : 675)	θ value	θ > 10 (rank : 1112)
Query Neighborhood Hits	872	Target Neighborhood Hits	157	Shared Neighborhood Hits	59
SwissProt Accessions	Q9ESJ4, Q68G72	Gene names	Nckipsd, Spin90, Wasbp
Domain Architecture	No domain graphic available
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (N-WASP-interacting protein, 90kDa) (Wiskott-Aldrich syndrome protein-binding protein WISH) (N-WASP-binding protein).

CO6A1_MOUSE
NC score	0.057441 (rank : 676)	θ value	θ > 10 (rank : 939)
Query Neighborhood Hits	872	Target Neighborhood Hits	241	Shared Neighborhood Hits	71
SwissProt Accessions	Q04857	Gene names	Col6a1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

PTN23_HUMAN
NC score	0.057420 (rank : 677)	θ value	0.0113563 (rank : 205)
Query Neighborhood Hits	872	Target Neighborhood Hits	646	Shared Neighborhood Hits	149
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

CITE4_MOUSE
NC score	0.057163 (rank : 678)	θ value	0.21417 (rank : 362)
Query Neighborhood Hits	872	Target Neighborhood Hits	73	Shared Neighborhood Hits	23
SwissProt Accessions	Q9WUL8, Q66JX0, Q8R176, Q9CZV4	Gene names	Cited4, Mrg2
Domain Architecture	No domain graphic available
Description	Cbp/p300-interacting transactivator 4 (MSG1-related protein 2) (MRG- 2).

NFRKB_MOUSE
NC score	0.057071 (rank : 679)	θ value	θ > 10 (rank : 1052)
Query Neighborhood Hits	872	Target Neighborhood Hits	393	Shared Neighborhood Hits	122
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

WDR33_HUMAN
NC score	0.057035 (rank : 680)	θ value	0.00509761 (rank : 177)
Query Neighborhood Hits	872	Target Neighborhood Hits	638	Shared Neighborhood Hits	142
SwissProt Accessions	Q9C0J8	Gene names	WDR33, WDC146
Domain Architecture
Description	WD repeat protein 33 (WD repeat protein WDC146).

UN13B_HUMAN
NC score	0.056882 (rank : 681)	θ value	θ > 10 (rank : 1139)
Query Neighborhood Hits	872	Target Neighborhood Hits	217	Shared Neighborhood Hits	32
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

HCN4_MOUSE
NC score	0.056776 (rank : 682)	θ value	0.00020696 (rank : 97)
Query Neighborhood Hits	872	Target Neighborhood Hits	284	Shared Neighborhood Hits	87
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

MUC1_MOUSE
NC score	0.056665 (rank : 683)	θ value	θ > 10 (rank : 1045)
Query Neighborhood Hits	872	Target Neighborhood Hits	388	Shared Neighborhood Hits	73
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

SMOO_HUMAN
NC score	0.056654 (rank : 684)	θ value	θ > 10 (rank : 1100)
Query Neighborhood Hits	872	Target Neighborhood Hits	391	Shared Neighborhood Hits	120
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

NUP53_MOUSE
NC score	0.056628 (rank : 685)	θ value	4.03905 (rank : 688)
Query Neighborhood Hits	872	Target Neighborhood Hits	94	Shared Neighborhood Hits	54
SwissProt Accessions	Q8R4R6, Q9D7J2	Gene names	Nup35, Mp44, Nup53
Domain Architecture	No domain graphic available
Description	Nucleoporin NUP53 (Nuclear pore complex protein Nup53) (Nucleoporin Nup35) (35 kDa nucleoporin) (Mitotic phosphoprotein 44) (MP-44).

RPTN_MOUSE
NC score	0.056603 (rank : 686)	θ value	θ > 10 (rank : 1087)
Query Neighborhood Hits	872	Target Neighborhood Hits	650	Shared Neighborhood Hits	106
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

GAK5_HUMAN
NC score	0.056517 (rank : 687)	θ value	θ > 10 (rank : 1001)
Query Neighborhood Hits	872	Target Neighborhood Hits	429	Shared Neighborhood Hits	211
SwissProt Accessions	P62684	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K113 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

ETV5_MOUSE
NC score	0.056453 (rank : 688)	θ value	0.0961366 (rank : 307)
Query Neighborhood Hits	872	Target Neighborhood Hits	328	Shared Neighborhood Hits	148
SwissProt Accessions	Q9CXC9, Q3TG49, Q8C0F3, Q9JHB1	Gene names	Etv5
Domain Architecture	No domain graphic available
Description	ETS translocation variant 5.

MN1_HUMAN
NC score	0.056367 (rank : 689)	θ value	6.88961 (rank : 784)
Query Neighborhood Hits	872	Target Neighborhood Hits	196	Shared Neighborhood Hits	71
SwissProt Accessions	Q10571	Gene names	MN1
Domain Architecture	No domain graphic available
Description	Probable tumor suppressor protein MN1.

SPRR3_HUMAN
NC score	0.056352 (rank : 690)	θ value	θ > 10 (rank : 1115)
Query Neighborhood Hits	872	Target Neighborhood Hits	102	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UBC9, O75597, Q4ZGI7, Q5T525, Q8NET7, Q9UDG3	Gene names	SPRR3, SPRC
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta) (Esophagin) (22 kDa pancornulin).

PRG4_MOUSE
NC score	0.056346 (rank : 691)	θ value	θ > 10 (rank : 1078)
Query Neighborhood Hits	872	Target Neighborhood Hits	624	Shared Neighborhood Hits	120
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

CASC3_MOUSE
NC score	0.056295 (rank : 692)	θ value	θ > 10 (rank : 908)
Query Neighborhood Hits	872	Target Neighborhood Hits	333	Shared Neighborhood Hits	99
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

IF4B_HUMAN
NC score	0.056197 (rank : 693)	θ value	θ > 10 (rank : 1015)
Query Neighborhood Hits	872	Target Neighborhood Hits	417	Shared Neighborhood Hits	104
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

CO6A1_HUMAN
NC score	0.056111 (rank : 694)	θ value	θ > 10 (rank : 938)
Query Neighborhood Hits	872	Target Neighborhood Hits	264	Shared Neighborhood Hits	78
SwissProt Accessions	P12109, O00117, O00118, Q14040, Q14041, Q16258	Gene names	COL6A1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

DCP1A_HUMAN
NC score	0.056110 (rank : 695)	θ value	θ > 10 (rank : 964)
Query Neighborhood Hits	872	Target Neighborhood Hits	228	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NPI6	Gene names	DCP1A, SMIF
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (Smad4-interacting transcriptional co-activator).

CN155_HUMAN
NC score	0.056064 (rank : 696)	θ value	θ > 10 (rank : 929)
Query Neighborhood Hits	872	Target Neighborhood Hits	385	Shared Neighborhood Hits	79
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

CENA2_HUMAN
NC score	0.055979 (rank : 697)	θ value	θ > 10 (rank : 917)
Query Neighborhood Hits	872	Target Neighborhood Hits	83	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

FA13A_MOUSE
NC score	0.055775 (rank : 698)	θ value	θ > 10 (rank : 983)
Query Neighborhood Hits	872	Target Neighborhood Hits	83	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BGI4, Q8BZ91	Gene names	Fam13a1, Precm1
Domain Architecture	No domain graphic available
Description	Protein FAM13A1 (Precm1 protein).

TP53B_MOUSE
NC score	0.055691 (rank : 699)	θ value	θ > 10 (rank : 1132)
Query Neighborhood Hits	872	Target Neighborhood Hits	644	Shared Neighborhood Hits	130
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TCOF_MOUSE
NC score	0.055643 (rank : 700)	θ value	θ > 10 (rank : 1127)
Query Neighborhood Hits	872	Target Neighborhood Hits	471	Shared Neighborhood Hits	91
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

GAK4_HUMAN
NC score	0.055555 (rank : 701)	θ value	θ > 10 (rank : 1000)
Query Neighborhood Hits	872	Target Neighborhood Hits	415	Shared Neighborhood Hits	202
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

EDA_MOUSE
NC score	0.055401 (rank : 702)	θ value	θ > 10 (rank : 972)
Query Neighborhood Hits	872	Target Neighborhood Hits	141	Shared Neighborhood Hits	66
SwissProt Accessions	O54693, O35705, Q9QWJ8, Q9QZ01, Q9QZ02	Gene names	Eda, Ed1, Ta
Domain Architecture
Description	Ectodysplasin-A (EDA protein homolog) (Tabby protein) [Contains: Ectodysplasin-A, membrane form; Ectodysplasin-A, secreted form].

MYO10_HUMAN
NC score	0.055320 (rank : 703)	θ value	θ > 10 (rank : 1047)
Query Neighborhood Hits	872	Target Neighborhood Hits	920	Shared Neighborhood Hits	75
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

GAK11_HUMAN
NC score	0.055256 (rank : 704)	θ value	θ > 10 (rank : 998)
Query Neighborhood Hits	872	Target Neighborhood Hits	409	Shared Neighborhood Hits	200
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

CENG3_MOUSE
NC score	0.055183 (rank : 705)	θ value	θ > 10 (rank : 922)
Query Neighborhood Hits	872	Target Neighborhood Hits	467	Shared Neighborhood Hits	40
SwissProt Accessions	Q8VHH5, Q812F7	Gene names	Centg3, Agap3
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

HGS_HUMAN
NC score	0.055173 (rank : 706)	θ value	θ > 10 (rank : 1011)
Query Neighborhood Hits	872	Target Neighborhood Hits	517	Shared Neighborhood Hits	109
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

SHLB1_MOUSE
NC score	0.055009 (rank : 707)	θ value	θ > 10 (rank : 1095)
Query Neighborhood Hits	872	Target Neighborhood Hits	101	Shared Neighborhood Hits	66
SwissProt Accessions	Q9JK48, Q8CDS9, Q8VI52, Q9CT31	Gene names	Sh3glb1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1).

SEM6C_MOUSE
NC score	0.055006 (rank : 708)	θ value	0.813845 (rank : 475)
Query Neighborhood Hits	872	Target Neighborhood Hits	352	Shared Neighborhood Hits	189
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

ARHGC_HUMAN
NC score	0.054985 (rank : 709)	θ value	θ > 10 (rank : 892)
Query Neighborhood Hits	872	Target Neighborhood Hits	351	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

RNC_HUMAN
NC score	0.054957 (rank : 710)	θ value	0.279714 (rank : 382)
Query Neighborhood Hits	872	Target Neighborhood Hits	176	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NRR4, Q7Z5V2, Q86YH0, Q9NW73, Q9Y2V9, Q9Y4Y0	Gene names	RNASEN, RN3, RNASE3L
Domain Architecture
Description	Ribonuclease III (EC 3.1.26.3) (RNase III) (Drosha) (p241).

COEA1_MOUSE
NC score	0.054882 (rank : 711)	θ value	0.00298849 (rank : 151)
Query Neighborhood Hits	872	Target Neighborhood Hits	402	Shared Neighborhood Hits	95
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

FGD6_HUMAN
NC score	0.054871 (rank : 712)	θ value	θ > 10 (rank : 994)
Query Neighborhood Hits	872	Target Neighborhood Hits	237	Shared Neighborhood Hits	38
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

GAK2_HUMAN
NC score	0.054855 (rank : 713)	θ value	θ > 10 (rank : 999)
Query Neighborhood Hits	872	Target Neighborhood Hits	406	Shared Neighborhood Hits	197
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

ELN_HUMAN
NC score	0.054773 (rank : 714)	θ value	θ > 10 (rank : 973)
Query Neighborhood Hits	872	Target Neighborhood Hits	85	Shared Neighborhood Hits	36
SwissProt Accessions	P15502, O15336, O15337, Q14233, Q14234, Q14235, Q14238, Q6P0L4, Q6ZWJ6, Q75MU5, Q7Z316, Q7Z3F5, Q9UMF5	Gene names	ELN
Domain Architecture	No domain graphic available
Description	Elastin precursor (Tropoelastin).

ZN687_HUMAN
NC score	0.054667 (rank : 715)	θ value	8.99809 (rank : 872)
Query Neighborhood Hits	872	Target Neighborhood Hits	1244	Shared Neighborhood Hits	322
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

TENS4_HUMAN
NC score	0.054666 (rank : 716)	θ value	θ > 10 (rank : 1128)
Query Neighborhood Hits	872	Target Neighborhood Hits	214	Shared Neighborhood Hits	81
SwissProt Accessions	Q8IZW8, Q71RB7, Q8WV64, Q96JV4	Gene names	TNS4, CTEN
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor (C-terminal tensin-like protein).

SH22A_HUMAN
NC score	0.054661 (rank : 717)	θ value	0.0431538 (rank : 268)
Query Neighborhood Hits	872	Target Neighborhood Hits	144	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NP31, O43817, Q9UPA7	Gene names	SH2D2A, SCAP, TSAD, VRAP
Domain Architecture
Description	SH2 domain protein 2A (T cell-specific adapter protein) (TSAd) (VEGF receptor-associated protein) (SH2 domain-containing adapter protein).

BI2L1_HUMAN
NC score	0.054657 (rank : 718)	θ value	4.03905 (rank : 674)
Query Neighborhood Hits	872	Target Neighborhood Hits	156	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UHR4, Q75L21, Q75L22, Q96CV4, Q9Y2M8	Gene names	BAIAP2L1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

FA13A_HUMAN
NC score	0.054601 (rank : 719)	θ value	θ > 10 (rank : 982)
Query Neighborhood Hits	872	Target Neighborhood Hits	102	Shared Neighborhood Hits	5
SwissProt Accessions	O94988, Q8NBA3	Gene names	FAM13A1, KIAA0914
Domain Architecture	No domain graphic available
Description	Protein FAM13A1.

CENA1_HUMAN
NC score	0.054592 (rank : 720)	θ value	θ > 10 (rank : 916)
Query Neighborhood Hits	872	Target Neighborhood Hits	87	Shared Neighborhood Hits	13
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

SGIP1_HUMAN
NC score	0.054578 (rank : 721)	θ value	5.27518 (rank : 738)
Query Neighborhood Hits	872	Target Neighborhood Hits	198	Shared Neighborhood Hits	83
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

COLQ_HUMAN
NC score	0.054433 (rank : 722)	θ value	θ > 10 (rank : 948)
Query Neighborhood Hits	872	Target Neighborhood Hits	193	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y215, Q6DK18, Q6YH18, Q6YH19, Q6YH20, Q6YH21, Q9NP18, Q9NP19, Q9NP20, Q9NP21, Q9NP22, Q9NP23, Q9NP24, Q9UP88	Gene names	COLQ
Domain Architecture	No domain graphic available
Description	Acetylcholinesterase collagenic tail peptide precursor (AChE Q subunit) (Acetylcholinesterase-associated collagen).

LR37A_HUMAN
NC score	0.054266 (rank : 723)	θ value	θ > 10 (rank : 1028)
Query Neighborhood Hits	872	Target Neighborhood Hits	720	Shared Neighborhood Hits	141
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

NCOR2_HUMAN
NC score	0.054238 (rank : 724)	θ value	θ > 10 (rank : 1049)
Query Neighborhood Hits	872	Target Neighborhood Hits	870	Shared Neighborhood Hits	191
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

PSMF1_MOUSE
NC score	0.054222 (rank : 725)	θ value	8.99809 (rank : 854)
Query Neighborhood Hits	872	Target Neighborhood Hits	85	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BHL8, Q8C0G9	Gene names	Psmf1
Domain Architecture	No domain graphic available
Description	Proteasome inhibitor PI31 subunit.

CENG3_HUMAN
NC score	0.054182 (rank : 726)	θ value	θ > 10 (rank : 921)
Query Neighborhood Hits	872	Target Neighborhood Hits	455	Shared Neighborhood Hits	35
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

UN13B_MOUSE
NC score	0.054166 (rank : 727)	θ value	θ > 10 (rank : 1140)
Query Neighborhood Hits	872	Target Neighborhood Hits	210	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

SRBP1_HUMAN
NC score	0.054127 (rank : 728)	θ value	0.813845 (rank : 478)
Query Neighborhood Hits	872	Target Neighborhood Hits	225	Shared Neighborhood Hits	65
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

DIAP3_MOUSE
NC score	0.054051 (rank : 729)	θ value	5.27518 (rank : 713)
Query Neighborhood Hits	872	Target Neighborhood Hits	221	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Z207	Gene names	Diaph3, Diap3
Domain Architecture
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3) (mDIA2) (p134mDIA2).

EDA_HUMAN
NC score	0.054029 (rank : 730)	θ value	θ > 10 (rank : 971)
Query Neighborhood Hits	872	Target Neighborhood Hits	134	Shared Neighborhood Hits	66
SwissProt Accessions	Q92838, O75910, Q5JUM7, Q9UP77, Q9Y6L0, Q9Y6L1, Q9Y6L2, Q9Y6L3, Q9Y6L4	Gene names	EDA, ED1
Domain Architecture
Description	Ectodysplasin-A (Ectodermal dysplasia protein) (EDA protein) [Contains: Ectodysplasin-A, membrane form; Ectodysplasin-A, secreted form].

NOLC1_HUMAN
NC score	0.053984 (rank : 731)	θ value	θ > 10 (rank : 1053)
Query Neighborhood Hits	872	Target Neighborhood Hits	452	Shared Neighborhood Hits	72
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

ES8L3_HUMAN
NC score	0.053963 (rank : 732)	θ value	θ > 10 (rank : 980)
Query Neighborhood Hits	872	Target Neighborhood Hits	206	Shared Neighborhood Hits	90
SwissProt Accessions	Q8TE67, Q5T8Q6, Q5T8Q7, Q5T8Q8, Q96E47, Q9H719	Gene names	EPS8L3, EPS8R3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

EHMT2_MOUSE
NC score	0.053899 (rank : 733)	θ value	2.36792 (rank : 597)
Query Neighborhood Hits	872	Target Neighborhood Hits	750	Shared Neighborhood Hits	175
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

CO6A2_HUMAN
NC score	0.053850 (rank : 734)	θ value	θ > 10 (rank : 940)
Query Neighborhood Hits	872	Target Neighborhood Hits	249	Shared Neighborhood Hits	79
SwissProt Accessions	P12110, Q13909, Q13910, Q13911, Q14049, Q16259, Q16597, Q9UML3	Gene names	COL6A2
Domain Architecture
Description	Collagen alpha-2(VI) chain precursor.

CNOT3_MOUSE
NC score	0.053772 (rank : 735)	θ value	θ > 10 (rank : 930)
Query Neighborhood Hits	872	Target Neighborhood Hits	504	Shared Neighborhood Hits	116
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

DOCK1_HUMAN
NC score	0.053673 (rank : 736)	θ value	2.36792 (rank : 595)
Query Neighborhood Hits	872	Target Neighborhood Hits	191	Shared Neighborhood Hits	86
SwissProt Accessions	Q14185	Gene names	DOCK1
Domain Architecture
Description	Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180).

ENAM_MOUSE
NC score	0.053622 (rank : 737)	θ value	θ > 10 (rank : 976)
Query Neighborhood Hits	872	Target Neighborhood Hits	229	Shared Neighborhood Hits	89
SwissProt Accessions	O55196	Gene names	Enam
Domain Architecture	No domain graphic available
Description	Enamelin precursor.

SHLB1_HUMAN
NC score	0.053575 (rank : 738)	θ value	θ > 10 (rank : 1094)
Query Neighborhood Hits	872	Target Neighborhood Hits	96	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Y371, Q9H3Z0, Q9NR47, Q9NYA9	Gene names	SH3GLB1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1) (Bax- interacting factor 1) (Bif-1).

RP3A_MOUSE
NC score	0.053525 (rank : 739)	θ value	8.99809 (rank : 857)
Query Neighborhood Hits	872	Target Neighborhood Hits	510	Shared Neighborhood Hits	173
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

ARHGC_MOUSE
NC score	0.053342 (rank : 740)	θ value	θ > 10 (rank : 893)
Query Neighborhood Hits	872	Target Neighborhood Hits	344	Shared Neighborhood Hits	53
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

MARCS_MOUSE
NC score	0.053271 (rank : 741)	θ value	θ > 10 (rank : 1036)
Query Neighborhood Hits	872	Target Neighborhood Hits	227	Shared Neighborhood Hits	55
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

CO6A2_MOUSE
NC score	0.052990 (rank : 742)	θ value	θ > 10 (rank : 941)
Query Neighborhood Hits	872	Target Neighborhood Hits	260	Shared Neighborhood Hits	79
SwissProt Accessions	Q02788, Q05505	Gene names	Col6a2
Domain Architecture
Description	Collagen alpha-2(VI) chain precursor.

CDN1C_HUMAN
NC score	0.052877 (rank : 743)	θ value	θ > 10 (rank : 913)
Query Neighborhood Hits	872	Target Neighborhood Hits	168	Shared Neighborhood Hits	65
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

CSTFT_HUMAN
NC score	0.052831 (rank : 744)	θ value	0.00228821 (rank : 143)
Query Neighborhood Hits	872	Target Neighborhood Hits	292	Shared Neighborhood Hits	56
SwissProt Accessions	Q9H0L4, O75174, Q53HK6, Q7LGE8, Q8N6T1	Gene names	CSTF2T, KIAA0689
Domain Architecture	No domain graphic available
Description	Cleavage stimulation factor 64 kDa subunit, tau variant (CSTF 64 kDa subunit, tau variant) (CF-1 64 kDa subunit, tau variant) (TauCstF-64).

FARP2_MOUSE
NC score	0.052823 (rank : 745)	θ value	θ > 10 (rank : 987)
Query Neighborhood Hits	872	Target Neighborhood Hits	209	Shared Neighborhood Hits	49
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

MARCO_MOUSE
NC score	0.052752 (rank : 746)	θ value	θ > 10 (rank : 1034)
Query Neighborhood Hits	872	Target Neighborhood Hits	242	Shared Neighborhood Hits	63
SwissProt Accessions	Q60754	Gene names	Marco
Domain Architecture
Description	Macrophage receptor MARCO (Macrophage receptor with collagenous structure).

SYN2_HUMAN
NC score	0.052669 (rank : 747)	θ value	θ > 10 (rank : 1120)
Query Neighborhood Hits	872	Target Neighborhood Hits	213	Shared Neighborhood Hits	73
SwissProt Accessions	Q92777	Gene names	SYN2
Domain Architecture
Description	Synapsin-2 (Synapsin II).

GAK6_HUMAN
NC score	0.052597 (rank : 748)	θ value	θ > 10 (rank : 1002)
Query Neighborhood Hits	872	Target Neighborhood Hits	392	Shared Neighborhood Hits	195
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

CIZ1_HUMAN
NC score	0.052424 (rank : 749)	θ value	θ > 10 (rank : 925)
Query Neighborhood Hits	872	Target Neighborhood Hits	359	Shared Neighborhood Hits	87
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

CEBPE_HUMAN
NC score	0.052289 (rank : 750)	θ value	2.36792 (rank : 587)
Query Neighborhood Hits	872	Target Neighborhood Hits	236	Shared Neighborhood Hits	106
SwissProt Accessions	Q15744, Q15745, Q8IYI2, Q99803	Gene names	CEBPE
Domain Architecture
Description	CCAAT/enhancer-binding protein epsilon (C/EBP epsilon).

RASA1_HUMAN
NC score	0.052273 (rank : 751)	θ value	θ > 10 (rank : 1082)
Query Neighborhood Hits	872	Target Neighborhood Hits	258	Shared Neighborhood Hits	48
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

FARP2_HUMAN
NC score	0.051953 (rank : 752)	θ value	θ > 10 (rank : 986)
Query Neighborhood Hits	872	Target Neighborhood Hits	240	Shared Neighborhood Hits	57
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

DCC_MOUSE
NC score	0.051915 (rank : 753)	θ value	0.0330416 (rank : 250)
Query Neighborhood Hits	872	Target Neighborhood Hits	896	Shared Neighborhood Hits	206
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

MAP4_HUMAN
NC score	0.051907 (rank : 754)	θ value	θ > 10 (rank : 1033)
Query Neighborhood Hits	872	Target Neighborhood Hits	428	Shared Neighborhood Hits	108
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

DMRTD_MOUSE
NC score	0.051898 (rank : 755)	θ value	3.0926 (rank : 637)
Query Neighborhood Hits	872	Target Neighborhood Hits	72	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CGW9	Gene names	Dmrtc2, Dmrt7
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2 (Doublesex- and mab-3-related transcription factor 7).

GIT2_MOUSE
NC score	0.051768 (rank : 756)	θ value	θ > 10 (rank : 1005)
Query Neighborhood Hits	872	Target Neighborhood Hits	323	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

ARHG2_HUMAN
NC score	0.051760 (rank : 757)	θ value	θ > 10 (rank : 882)
Query Neighborhood Hits	872	Target Neighborhood Hits	142	Shared Neighborhood Hits	34
SwissProt Accessions	Q92974, O75142, Q15079	Gene names	ARHGEF2, KIAA0651, LFP40
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (GEF-H1 protein) (Proliferating cell nucleolar antigen p40).

SNIP_MOUSE
NC score	0.051602 (rank : 758)	θ value	0.0252991 (rank : 242)
Query Neighborhood Hits	872	Target Neighborhood Hits	319	Shared Neighborhood Hits	67
SwissProt Accessions	Q9QWI6, O70298	Gene names	P140, Kiaa1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

ZN598_HUMAN
NC score	0.051592 (rank : 759)	θ value	1.06291 (rank : 523)
Query Neighborhood Hits	872	Target Neighborhood Hits	339	Shared Neighborhood Hits	73
SwissProt Accessions	Q86UK7, Q8IW49, Q8N3D9, Q96FG3, Q9H7J3	Gene names	ZNF598
Domain Architecture	No domain graphic available
Description	Zinc finger protein 598.

EPS8_HUMAN
NC score	0.051584 (rank : 760)	θ value	θ > 10 (rank : 978)
Query Neighborhood Hits	872	Target Neighborhood Hits	151	Shared Neighborhood Hits	84
SwissProt Accessions	Q12929, Q8N6J0	Gene names	EPS8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

SYP2L_MOUSE
NC score	0.051498 (rank : 761)	θ value	8.99809 (rank : 864)
Query Neighborhood Hits	872	Target Neighborhood Hits	289	Shared Neighborhood Hits	75
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

BASP_HUMAN
NC score	0.051432 (rank : 762)	θ value	θ > 10 (rank : 901)
Query Neighborhood Hits	872	Target Neighborhood Hits	321	Shared Neighborhood Hits	66
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

SELV_HUMAN
NC score	0.051400 (rank : 763)	θ value	θ > 10 (rank : 1091)
Query Neighborhood Hits	872	Target Neighborhood Hits	118	Shared Neighborhood Hits	54
SwissProt Accessions	P59797	Gene names	SELV
Domain Architecture	No domain graphic available
Description	Selenoprotein V.

ARFG3_MOUSE
NC score	0.051346 (rank : 764)	θ value	θ > 10 (rank : 879)
Query Neighborhood Hits	872	Target Neighborhood Hits	80	Shared Neighborhood Hits	13
SwissProt Accessions	Q9D8S3, Q99KN8	Gene names	Arfgap3
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

SYN3_MOUSE
NC score	0.051328 (rank : 765)	θ value	θ > 10 (rank : 1121)
Query Neighborhood Hits	872	Target Neighborhood Hits	200	Shared Neighborhood Hits	72
SwissProt Accessions	Q8JZP2	Gene names	Syn3
Domain Architecture	No domain graphic available
Description	Synapsin-3 (Synapsin III).

C1QA_HUMAN
NC score	0.051268 (rank : 766)	θ value	θ > 10 (rank : 906)
Query Neighborhood Hits	872	Target Neighborhood Hits	179	Shared Neighborhood Hits	63
SwissProt Accessions	P02745, Q5T963	Gene names	C1QA
Domain Architecture
Description	Complement C1q subcomponent subunit A precursor.

EPS8_MOUSE
NC score	0.051164 (rank : 767)	θ value	θ > 10 (rank : 979)
Query Neighborhood Hits	872	Target Neighborhood Hits	157	Shared Neighborhood Hits	86
SwissProt Accessions	Q08509	Gene names	Eps8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

IWS1_HUMAN
NC score	0.051110 (rank : 768)	θ value	θ > 10 (rank : 1018)
Query Neighborhood Hits	872	Target Neighborhood Hits	1241	Shared Neighborhood Hits	159
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

SNX9_HUMAN
NC score	0.051079 (rank : 769)	θ value	θ > 10 (rank : 1105)
Query Neighborhood Hits	872	Target Neighborhood Hits	148	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y5X1, Q9BSI7, Q9BVM1, Q9UJH6, Q9UP20	Gene names	SNX9, SH3PX1
Domain Architecture
Description	Sorting nexin-9 (SH3 and PX domain-containing protein 1) (SDP1 protein).

TB182_HUMAN
NC score	0.051056 (rank : 770)	θ value	θ > 10 (rank : 1126)
Query Neighborhood Hits	872	Target Neighborhood Hits	414	Shared Neighborhood Hits	116
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

ARFG3_HUMAN
NC score	0.050969 (rank : 771)	θ value	θ > 10 (rank : 878)
Query Neighborhood Hits	872	Target Neighborhood Hits	56	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NP61, Q9BSC6, Q9H9J0, Q9NT10, Q9NUP5, Q9Y4V3, Q9Y4V4	Gene names	ARFGAP3, ARFGAP1
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

PDLI7_HUMAN
NC score	0.050924 (rank : 772)	θ value	θ > 10 (rank : 1065)
Query Neighborhood Hits	872	Target Neighborhood Hits	547	Shared Neighborhood Hits	170
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

GIT1_HUMAN
NC score	0.050921 (rank : 773)	θ value	θ > 10 (rank : 1003)
Query Neighborhood Hits	872	Target Neighborhood Hits	336	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

MARCS_HUMAN
NC score	0.050894 (rank : 774)	θ value	θ > 10 (rank : 1035)
Query Neighborhood Hits	872	Target Neighborhood Hits	204	Shared Neighborhood Hits	57
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

SH23A_HUMAN
NC score	0.050572 (rank : 775)	θ value	0.0961366 (rank : 312)
Query Neighborhood Hits	872	Target Neighborhood Hits	149	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BRG2, Q9Y2X4	Gene names	SH2D3A, NSP1
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3A (Novel SH2-containing protein 1).

TSC1_HUMAN
NC score	0.050516 (rank : 776)	θ value	0.0252991 (rank : 246)
Query Neighborhood Hits	872	Target Neighborhood Hits	765	Shared Neighborhood Hits	97
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

GIT1_MOUSE
NC score	0.050198 (rank : 777)	θ value	θ > 10 (rank : 1004)
Query Neighborhood Hits	872	Target Neighborhood Hits	341	Shared Neighborhood Hits	28
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

STS2_HUMAN
NC score	0.050156 (rank : 778)	θ value	θ > 10 (rank : 1119)
Query Neighborhood Hits	872	Target Neighborhood Hits	108	Shared Neighborhood Hits	67
SwissProt Accessions	P57075, Q6HA34, Q6HA35, Q6ISI6, Q6ISK3, Q6ISS9	Gene names	UBASH3A, STS2
Domain Architecture
Description	Suppressor of T-cell receptor signaling 2 (STS-2) (Cbl-interacting protein 4) (CLIP4) (T-cell ubiquitin ligand) (TULA).

ARHG2_MOUSE
NC score	0.050137 (rank : 779)	θ value	θ > 10 (rank : 883)
Query Neighborhood Hits	872	Target Neighborhood Hits	120	Shared Neighborhood Hits	30
SwissProt Accessions	Q60875, O09115	Gene names	Arhgef2, Lbcl1, Lfc
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (Lymphoid blast crisis- like 1) (LBC'S first cousin) (Oncogene LFC) (RHOBIN).

HSF1_MOUSE
NC score	0.050064 (rank : 780)	θ value	6.88961 (rank : 776)
Query Neighborhood Hits	872	Target Neighborhood Hits	267	Shared Neighborhood Hits	99
SwissProt Accessions	P38532, O70462	Gene names	Hsf1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

ANXA7_MOUSE
NC score	0.049958 (rank : 781)	θ value	0.00035302 (rank : 106)
Query Neighborhood Hits	872	Target Neighborhood Hits	142	Shared Neighborhood Hits	54
SwissProt Accessions	Q07076	Gene names	Anxa7, Anx7
Domain Architecture
Description	Annexin A7 (Annexin VII) (Synexin).

PP1RA_MOUSE
NC score	0.049884 (rank : 782)	θ value	5.27518 (rank : 732)
Query Neighborhood Hits	872	Target Neighborhood Hits	175	Shared Neighborhood Hits	62
SwissProt Accessions	Q80W00, Q811B6, Q8C6T7, Q8K2U8	Gene names	Ppp1r10, Cat53
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 1 regulatory subunit 10 (MHC class I region proline-rich protein CAT53).

CNOT3_HUMAN
NC score	0.049609 (rank : 783)	θ value	6.88961 (rank : 761)
Query Neighborhood Hits	872	Target Neighborhood Hits	425	Shared Neighborhood Hits	89
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

IQEC2_MOUSE
NC score	0.049464 (rank : 784)	θ value	0.163984 (rank : 343)
Query Neighborhood Hits	872	Target Neighborhood Hits	417	Shared Neighborhood Hits	110
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

LDB3_HUMAN
NC score	0.049222 (rank : 785)	θ value	0.0113563 (rank : 202)
Query Neighborhood Hits	872	Target Neighborhood Hits	497	Shared Neighborhood Hits	118
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

CSTF2_HUMAN
NC score	0.048890 (rank : 786)	θ value	8.99809 (rank : 814)
Query Neighborhood Hits	872	Target Neighborhood Hits	296	Shared Neighborhood Hits	69
SwissProt Accessions	P33240, Q5H951, Q6LA74, Q8N502	Gene names	CSTF2
Domain Architecture
Description	Cleavage stimulation factor 64 kDa subunit (CSTF 64 kDa subunit) (CF-1 64 kDa subunit) (CstF-64).

M3K11_HUMAN
NC score	0.048740 (rank : 787)	θ value	0.00390308 (rank : 162)
Query Neighborhood Hits	872	Target Neighborhood Hits	1136	Shared Neighborhood Hits	196
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

IQEC2_HUMAN
NC score	0.048635 (rank : 788)	θ value	0.163984 (rank : 342)
Query Neighborhood Hits	872	Target Neighborhood Hits	403	Shared Neighborhood Hits	108
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

CEP68_HUMAN
NC score	0.048350 (rank : 789)	θ value	0.21417 (rank : 361)
Query Neighborhood Hits	872	Target Neighborhood Hits	128	Shared Neighborhood Hits	40
SwissProt Accessions	Q76N32, O60326, Q9BQ18, Q9UDM9	Gene names	CEP68, KIAA0582
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 68 kDa (Cep68 protein).

FIP1_MOUSE
NC score	0.047701 (rank : 790)	θ value	0.279714 (rank : 378)
Query Neighborhood Hits	872	Target Neighborhood Hits	120	Shared Neighborhood Hits	32
SwissProt Accessions	Q9D824, Q8BWX7, Q99LH0, Q9DBB2	Gene names	Fip1l1
Domain Architecture	No domain graphic available
Description	Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1).

LEUK_HUMAN
NC score	0.047509 (rank : 791)	θ value	8.99809 (rank : 838)
Query Neighborhood Hits	872	Target Neighborhood Hits	213	Shared Neighborhood Hits	61
SwissProt Accessions	P16150	Gene names	SPN, CD43
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Galactoglycoprotein) (GALGP) (CD43 antigen).

REXO1_MOUSE
NC score	0.047370 (rank : 792)	θ value	0.47712 (rank : 419)
Query Neighborhood Hits	872	Target Neighborhood Hits	166	Shared Neighborhood Hits	44
SwissProt Accessions	Q7TT28, Q3UMP1, Q69ZR0, Q6NSQ6, Q6PI95, Q9DA29	Gene names	Rexo1, Kiaa1138, Tceb3bp1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Transcription elongation factor B polypeptide 3-binding protein 1).

FOXN1_MOUSE
NC score	0.047343 (rank : 793)	θ value	4.03905 (rank : 681)
Query Neighborhood Hits	872	Target Neighborhood Hits	300	Shared Neighborhood Hits	126
SwissProt Accessions	Q61575	Gene names	Foxn1, Fkh19, Hfh11, Whn
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/forkhead homolog 11) (HFH-11).

MIA2_MOUSE
NC score	0.047245 (rank : 794)	θ value	1.06291 (rank : 503)
Query Neighborhood Hits	872	Target Neighborhood Hits	109	Shared Neighborhood Hits	34
SwissProt Accessions	Q91ZV0	Gene names	Mia2
Domain Architecture	No domain graphic available
Description	Melanoma inhibitory activity protein 2 precursor.

M3K9_HUMAN
NC score	0.047217 (rank : 795)	θ value	0.00020696 (rank : 98)
Query Neighborhood Hits	872	Target Neighborhood Hits	1123	Shared Neighborhood Hits	176
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

STON1_MOUSE
NC score	0.047040 (rank : 796)	θ value	0.0252991 (rank : 245)
Query Neighborhood Hits	872	Target Neighborhood Hits	50	Shared Neighborhood Hits	17
SwissProt Accessions	Q8CDJ8, Q8CDL8, Q9D5T3	Gene names	Ston1, Salf, Sblf, Stn1
Domain Architecture
Description	Stonin-1 (Stoned B-like factor).

TFG_HUMAN
NC score	0.046717 (rank : 797)	θ value	8.99809 (rank : 866)
Query Neighborhood Hits	872	Target Neighborhood Hits	122	Shared Neighborhood Hits	44
SwissProt Accessions	Q92734, Q15656	Gene names	TFG
Domain Architecture
Description	Protein TFG (TRK-fused gene protein).

IER5_MOUSE
NC score	0.046295 (rank : 798)	θ value	0.813845 (rank : 459)
Query Neighborhood Hits	872	Target Neighborhood Hits	110	Shared Neighborhood Hits	35
SwissProt Accessions	O89113, Q8CGI0	Gene names	Ier5
Domain Architecture	No domain graphic available
Description	Immediate early response gene 5 protein.

RIN3_HUMAN
NC score	0.045936 (rank : 799)	θ value	0.813845 (rank : 472)
Query Neighborhood Hits	872	Target Neighborhood Hits	227	Shared Neighborhood Hits	74
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

GR65_HUMAN
NC score	0.045913 (rank : 800)	θ value	0.813845 (rank : 458)
Query Neighborhood Hits	872	Target Neighborhood Hits	148	Shared Neighborhood Hits	71
SwissProt Accessions	Q9BQQ3, Q8N272, Q96H42	Gene names	GORASP1, GRASP65
Domain Architecture	No domain graphic available
Description	Golgi reassembly-stacking protein 1 (Golgi reassembly-stacking protein of 65 kDa) (GRASP65) (Golgi peripheral membrane protein p65) (Golgi phosphoprotein 5) (GOLPH5).

IF35_MOUSE
NC score	0.045630 (rank : 801)	θ value	8.99809 (rank : 830)
Query Neighborhood Hits	872	Target Neighborhood Hits	210	Shared Neighborhood Hits	77
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

DVL2_HUMAN
NC score	0.045349 (rank : 802)	θ value	0.00665767 (rank : 179)
Query Neighborhood Hits	872	Target Neighborhood Hits	223	Shared Neighborhood Hits	43
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

PER1_MOUSE
NC score	0.044844 (rank : 803)	θ value	0.0961366 (rank : 311)
Query Neighborhood Hits	872	Target Neighborhood Hits	235	Shared Neighborhood Hits	86
SwissProt Accessions	O35973	Gene names	Per1, Per, Rigui
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (mPER) (M-Rigui).

NMDE4_MOUSE
NC score	0.044746 (rank : 804)	θ value	1.09739e-05 (rank : 76)
Query Neighborhood Hits	872	Target Neighborhood Hits	158	Shared Neighborhood Hits	47
SwissProt Accessions	Q03391	Gene names	Grin2d
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D).

PRCC_HUMAN
NC score	0.044628 (rank : 805)	θ value	1.81305 (rank : 581)
Query Neighborhood Hits	872	Target Neighborhood Hits	109	Shared Neighborhood Hits	42
SwissProt Accessions	Q92733, O00665, O00724	Gene names	PRCC, TPRC
Domain Architecture	No domain graphic available
Description	Proline-rich protein PRCC (Papillary renal cell carcinoma translocation-associated gene protein).

TLE1_MOUSE
NC score	0.044230 (rank : 806)	θ value	0.813845 (rank : 481)
Query Neighborhood Hits	872	Target Neighborhood Hits	491	Shared Neighborhood Hits	147
SwissProt Accessions	Q62440	Gene names	Tle1, Grg1
Domain Architecture
Description	Transducin-like enhancer protein 1 (Groucho-related protein 1) (Grg- 1).

LDB3_MOUSE
NC score	0.044172 (rank : 807)	θ value	0.163984 (rank : 344)
Query Neighborhood Hits	872	Target Neighborhood Hits	510	Shared Neighborhood Hits	118
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

FIP1_HUMAN
NC score	0.044166 (rank : 808)	θ value	2.36792 (rank : 598)
Query Neighborhood Hits	872	Target Neighborhood Hits	118	Shared Neighborhood Hits	36
SwissProt Accessions	Q6UN15, Q499Y4, Q49AU3, Q7Z608, Q8WVN3, Q96F80, Q9H077	Gene names	FIP1L1, FIP1, RHE
Domain Architecture	No domain graphic available
Description	Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1) (Factor interacting with PAP) (hFip1) (Rearranged in hypereosinophilia).

FOXH1_HUMAN
NC score	0.044148 (rank : 809)	θ value	3.0926 (rank : 645)
Query Neighborhood Hits	872	Target Neighborhood Hits	258	Shared Neighborhood Hits	123
SwissProt Accessions	O75593	Gene names	FOXH1, FAST1, FAST2
Domain Architecture
Description	Forkhead box protein H1 (Forkhead activin signal transducer 1) (Fast- 1) (hFAST-1) (Forkhead activin signal transducer 2) (Fast-2).

B4GN4_HUMAN
NC score	0.044135 (rank : 810)	θ value	0.00869519 (rank : 185)
Query Neighborhood Hits	872	Target Neighborhood Hits	131	Shared Neighborhood Hits	37
SwissProt Accessions	Q76KP1, Q96LV2	Gene names	B4GALNT4
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 1 (EC 2.4.1.244) (NGalNAc-T1) (Beta- 1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4).

ANXA7_HUMAN
NC score	0.044060 (rank : 811)	θ value	0.0736092 (rank : 290)
Query Neighborhood Hits	872	Target Neighborhood Hits	168	Shared Neighborhood Hits	61
SwissProt Accessions	P20073	Gene names	ANXA7, ANX7, SNX
Domain Architecture
Description	Annexin A7 (Annexin VII) (Synexin).

HCN2_MOUSE
NC score	0.043806 (rank : 812)	θ value	8.99809 (rank : 828)
Query Neighborhood Hits	872	Target Neighborhood Hits	278	Shared Neighborhood Hits	91
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

K1949_MOUSE
NC score	0.043701 (rank : 813)	θ value	1.81305 (rank : 570)
Query Neighborhood Hits	872	Target Neighborhood Hits	134	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BQ30, Q3UDS6, Q8CEY9, Q8R3D8	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA1949 homolog.

ANX11_HUMAN
NC score	0.043687 (rank : 814)	θ value	0.0193708 (rank : 221)
Query Neighborhood Hits	872	Target Neighborhood Hits	192	Shared Neighborhood Hits	64
SwissProt Accessions	P50995	Gene names	ANXA11, ANX11
Domain Architecture
Description	Annexin A11 (Annexin XI) (Calcyclin-associated annexin 50) (CAP-50) (56 kDa autoantigen).

ANX11_MOUSE
NC score	0.043445 (rank : 815)	θ value	0.163984 (rank : 331)
Query Neighborhood Hits	872	Target Neighborhood Hits	200	Shared Neighborhood Hits	73
SwissProt Accessions	P97384	Gene names	Anxa11, Anx11
Domain Architecture
Description	Annexin A11 (Annexin XI) (Calcyclin-associated annexin 50) (CAP-50).

IF4G1_HUMAN
NC score	0.043107 (rank : 816)	θ value	3.0926 (rank : 650)
Query Neighborhood Hits	872	Target Neighborhood Hits	347	Shared Neighborhood Hits	110
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

EMIL2_HUMAN
NC score	0.042657 (rank : 817)	θ value	0.47712 (rank : 405)
Query Neighborhood Hits	872	Target Neighborhood Hits	573	Shared Neighborhood Hits	105
SwissProt Accessions	Q9BXX0, Q8NBH3, Q96JQ4	Gene names	EMILIN2
Domain Architecture
Description	EMILIN-2 precursor (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Protein FOAP-10).

CCD95_HUMAN
NC score	0.042044 (rank : 818)	θ value	1.06291 (rank : 486)
Query Neighborhood Hits	872	Target Neighborhood Hits	25	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NBZ0	Gene names	CCDC95
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 95.

M3KL4_HUMAN
NC score	0.041941 (rank : 819)	θ value	0.0736092 (rank : 295)
Query Neighborhood Hits	872	Target Neighborhood Hits	1087	Shared Neighborhood Hits	140
SwissProt Accessions	Q5TCX8, Q5TCX7, Q5TCX9, Q8WWN1, Q8WWN2, Q96JM1	Gene names	MLK4, KIAA1804
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase 4).

DEN1A_HUMAN
NC score	0.041799 (rank : 820)	θ value	1.38821 (rank : 531)
Query Neighborhood Hits	872	Target Neighborhood Hits	176	Shared Neighborhood Hits	76
SwissProt Accessions	Q8TEH3, Q5VWF0, Q8IVD6, Q9H796	Gene names	DENND1A
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

NBL1_HUMAN
NC score	0.041675 (rank : 821)	θ value	0.163984 (rank : 348)
Query Neighborhood Hits	872	Target Neighborhood Hits	22	Shared Neighborhood Hits	5
SwissProt Accessions	P41271, Q96L68	Gene names	NBL1, DAN
Domain Architecture
Description	Neuroblastoma suppressor of tumorigenicity 1 precursor (Zinc finger protein DAN) (N03).

PER1_HUMAN
NC score	0.041648 (rank : 822)	θ value	1.81305 (rank : 579)
Query Neighborhood Hits	872	Target Neighborhood Hits	215	Shared Neighborhood Hits	70
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

RANB9_HUMAN
NC score	0.041437 (rank : 823)	θ value	1.38821 (rank : 542)
Query Neighborhood Hits	872	Target Neighborhood Hits	179	Shared Neighborhood Hits	72
SwissProt Accessions	Q96S59, O94764, Q6P3T7, Q7LBR2, Q7Z7F9	Gene names	RANBP9, RANBPM
Domain Architecture	No domain graphic available
Description	Ran-binding protein 9 (RanBP9) (RanBP7) (Ran-binding protein M) (RanBPM) (BPM90) (BPM-L).

GFC1_HUMAN
NC score	0.041317 (rank : 824)	θ value	0.21417 (rank : 363)
Query Neighborhood Hits	872	Target Neighborhood Hits	95	Shared Neighborhood Hits	39
SwissProt Accessions	P63117	Gene names
Domain Architecture	No domain graphic available
Description	HERV-F(c)1_Xq21.33 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein].

PS1C2_HUMAN
NC score	0.041240 (rank : 825)	θ value	5.27518 (rank : 734)
Query Neighborhood Hits	872	Target Neighborhood Hits	66	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UIG4	Gene names	PSORS1C2, C6orf17, SPR1
Domain Architecture	No domain graphic available
Description	Psoriasis susceptibility 1 candidate gene 2 protein precursor (SPR1 protein).

DUT_HUMAN
NC score	0.040822 (rank : 826)	θ value	2.36792 (rank : 596)
Query Neighborhood Hits	872	Target Neighborhood Hits	52	Shared Neighborhood Hits	28
SwissProt Accessions	P33316, O14785, Q16708, Q16860, Q96Q81	Gene names	DUT
Domain Architecture
Description	Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial precursor (EC 3.6.1.23) (dUTPase) (dUTP pyrophosphatase).

RIN3_MOUSE
NC score	0.040703 (rank : 827)	θ value	6.88961 (rank : 788)
Query Neighborhood Hits	872	Target Neighborhood Hits	239	Shared Neighborhood Hits	83
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

K1949_HUMAN
NC score	0.040598 (rank : 828)	θ value	0.21417 (rank : 366)
Query Neighborhood Hits	872	Target Neighborhood Hits	121	Shared Neighborhood Hits	24
SwissProt Accessions	Q6NYC8, Q68CK8, Q6ZUJ6, Q8NDQ4, Q8TF52, Q9BRL9	Gene names	KIAA1949
Domain Architecture	No domain graphic available
Description	Protein KIAA1949.

NBL1_MOUSE
NC score	0.040389 (rank : 829)	θ value	0.279714 (rank : 380)
Query Neighborhood Hits	872	Target Neighborhood Hits	21	Shared Neighborhood Hits	5
SwissProt Accessions	Q61477	Gene names	Nbl1, Dan, Dana
Domain Architecture
Description	Neuroblastoma suppressor of tumorigenicity 1 precursor (Zinc finger protein DAN) (N03).

SMCA4_HUMAN
NC score	0.040378 (rank : 830)	θ value	1.06291 (rank : 512)
Query Neighborhood Hits	872	Target Neighborhood Hits	597	Shared Neighborhood Hits	127
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

CASC3_HUMAN
NC score	0.040228 (rank : 831)	θ value	1.06291 (rank : 485)
Query Neighborhood Hits	872	Target Neighborhood Hits	204	Shared Neighborhood Hits	49
SwissProt Accessions	O15234	Gene names	CASC3, MLN51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein) (Metastatic lymph node protein 51) (Protein MLN 51) (Protein barentsz) (Btz).

DMRTC_HUMAN
NC score	0.039956 (rank : 832)	θ value	0.163984 (rank : 338)
Query Neighborhood Hits	872	Target Neighborhood Hits	15	Shared Neighborhood Hits	5
SwissProt Accessions	Q5HYR2, Q5HYR0, Q5U5K2, Q8N6L3, Q96SD3	Gene names	DMRTC1
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C1.

NOTC2_HUMAN
NC score	0.039811 (rank : 833)	θ value	0.0148317 (rank : 213)
Query Neighborhood Hits	872	Target Neighborhood Hits	1113	Shared Neighborhood Hits	186
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

UBQL3_HUMAN
NC score	0.039722 (rank : 834)	θ value	0.62314 (rank : 447)
Query Neighborhood Hits	872	Target Neighborhood Hits	141	Shared Neighborhood Hits	64
SwissProt Accessions	Q9H347, Q9NRE0	Gene names	UBQLN3
Domain Architecture
Description	Ubiquilin-3.

IRS1_MOUSE
NC score	0.039407 (rank : 835)	θ value	0.62314 (rank : 435)
Query Neighborhood Hits	872	Target Neighborhood Hits	112	Shared Neighborhood Hits	30
SwissProt Accessions	P35569	Gene names	Irs1, Irs-1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

NMDE4_HUMAN
NC score	0.039400 (rank : 836)	θ value	0.00298849 (rank : 153)
Query Neighborhood Hits	872	Target Neighborhood Hits	133	Shared Neighborhood Hits	38
SwissProt Accessions	O15399	Gene names	GRIN2D
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D) (EB11).

FOG1_MOUSE
NC score	0.039353 (rank : 837)	θ value	8.99809 (rank : 824)
Query Neighborhood Hits	872	Target Neighborhood Hits	1237	Shared Neighborhood Hits	250
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

FREA_HUMAN
NC score	0.039223 (rank : 838)	θ value	0.000786445 (rank : 119)
Query Neighborhood Hits	872	Target Neighborhood Hits	205	Shared Neighborhood Hits	84
SwissProt Accessions	O43638, Q96D28	Gene names	FKHL18, FREAC10
Domain Architecture	No domain graphic available
Description	Forkhead-related transcription factor 10 (FREAC-10) (Forkhead-like 18 protein).

SOX17_MOUSE
NC score	0.039217 (rank : 839)	θ value	0.0961366 (rank : 314)
Query Neighborhood Hits	872	Target Neighborhood Hits	223	Shared Neighborhood Hits	90
SwissProt Accessions	Q61473, Q61472, Q62248	Gene names	Sox17, Sox-17
Domain Architecture
Description	Transcription factor SOX-17.

TLE1_HUMAN
NC score	0.039191 (rank : 840)	θ value	1.81305 (rank : 585)
Query Neighborhood Hits	872	Target Neighborhood Hits	485	Shared Neighborhood Hits	149
SwissProt Accessions	Q04724, Q5T3G4, Q969V9	Gene names	TLE1
Domain Architecture
Description	Transducin-like enhancer protein 1 (ESG1) (E(Sp1) homolog).

STON2_HUMAN
NC score	0.039066 (rank : 841)	θ value	0.125558 (rank : 327)
Query Neighborhood Hits	872	Target Neighborhood Hits	115	Shared Neighborhood Hits	29
SwissProt Accessions	Q8WXE9, Q6NT47, Q96RI7, Q96RU6	Gene names	STON2, STN2, STNB
Domain Architecture
Description	Stonin-2 (Stoned B).

TREF1_MOUSE
NC score	0.039012 (rank : 842)	θ value	0.0431538 (rank : 270)
Query Neighborhood Hits	872	Target Neighborhood Hits	682	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BXJ2, Q6PCQ4, Q80X25, Q810H8, Q8BY31	Gene names	Trerf1
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132).

RRBP1_MOUSE
NC score	0.038997 (rank : 843)	θ value	8.99809 (rank : 858)
Query Neighborhood Hits	872	Target Neighborhood Hits	1650	Shared Neighborhood Hits	170
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

K0460_MOUSE
NC score	0.038135 (rank : 844)	θ value	0.62314 (rank : 436)
Query Neighborhood Hits	872	Target Neighborhood Hits	374	Shared Neighborhood Hits	81
SwissProt Accessions	Q6NXI6, Q3U3L8, Q6ZQA7	Gene names	Kiaa0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

BTBD7_MOUSE
NC score	0.037885 (rank : 845)	θ value	0.0563607 (rank : 274)
Query Neighborhood Hits	872	Target Neighborhood Hits	228	Shared Neighborhood Hits	40
SwissProt Accessions	Q8CFE5, Q80TC3, Q8BZY9	Gene names	Btbd7, Kiaa1525
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 7.

PEX14_MOUSE
NC score	0.037603 (rank : 846)	θ value	0.62314 (rank : 443)
Query Neighborhood Hits	872	Target Neighborhood Hits	62	Shared Neighborhood Hits	16
SwissProt Accessions	Q9R0A0	Gene names	Pex14
Domain Architecture
Description	Peroxisomal membrane protein PEX14 (Peroxin-14) (Peroxisomal membrane anchor protein PEX14) (PTS1 receptor docking protein).

DEN1A_MOUSE
NC score	0.037375 (rank : 847)	θ value	1.06291 (rank : 492)
Query Neighborhood Hits	872	Target Neighborhood Hits	178	Shared Neighborhood Hits	71
SwissProt Accessions	Q8K382	Gene names	Dennd1a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

BORG3_HUMAN
NC score	0.037349 (rank : 848)	θ value	0.163984 (rank : 334)
Query Neighborhood Hits	872	Target Neighborhood Hits	36	Shared Neighborhood Hits	13
SwissProt Accessions	Q6NZY7, Q8TB51	Gene names	CDC42EP5, BORG3, CEP5
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 5 (Binder of Rho GTPases 3).

SYNP2_MOUSE
NC score	0.037270 (rank : 849)	θ value	4.03905 (rank : 697)
Query Neighborhood Hits	872	Target Neighborhood Hits	252	Shared Neighborhood Hits	57
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

FA53C_MOUSE
NC score	0.037270 (rank : 850)	θ value	0.0961366 (rank : 308)
Query Neighborhood Hits	872	Target Neighborhood Hits	40	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BXQ8, Q3U4J2	Gene names	Fam53c
Domain Architecture	No domain graphic available
Description	Protein FAM53C.

FUBP1_MOUSE
NC score	0.037209 (rank : 851)	θ value	5.27518 (rank : 720)
Query Neighborhood Hits	872	Target Neighborhood Hits	144	Shared Neighborhood Hits	61
SwissProt Accessions	Q91WJ8, Q8C0Y8	Gene names	Fubp1, D3Ertd330e
Domain Architecture
Description	Far upstream element-binding protein 1 (FUSE-binding protein 1) (FBP).

FUBP1_HUMAN
NC score	0.037070 (rank : 852)	θ value	5.27518 (rank : 719)
Query Neighborhood Hits	872	Target Neighborhood Hits	136	Shared Neighborhood Hits	58
SwissProt Accessions	Q96AE4, Q12828	Gene names	FUBP1
Domain Architecture
Description	Far upstream element-binding protein 1 (FUSE-binding protein 1) (FBP) (DNA helicase V) (HDH V).

CEP68_MOUSE
NC score	0.037025 (rank : 853)	θ value	6.88961 (rank : 760)
Query Neighborhood Hits	872	Target Neighborhood Hits	62	Shared Neighborhood Hits	10
SwissProt Accessions	Q8C0D9, Q3US49, Q5SW85, Q8R2V0	Gene names	Cep68
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 68 kDa (Cep68 protein).

GNAS1_HUMAN
NC score	0.037025 (rank : 854)	θ value	0.0431538 (rank : 262)
Query Neighborhood Hits	872	Target Neighborhood Hits	278	Shared Neighborhood Hits	91
SwissProt Accessions	Q5JWF2, O75684, O75685, Q5JW67, Q5JWF1, Q9NY42	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

INVS_MOUSE
NC score	0.036864 (rank : 855)	θ value	6.88961 (rank : 778)
Query Neighborhood Hits	872	Target Neighborhood Hits	609	Shared Neighborhood Hits	126
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

CSTF2_MOUSE
NC score	0.036567 (rank : 856)	θ value	4.03905 (rank : 677)
Query Neighborhood Hits	872	Target Neighborhood Hits	255	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BIQ5, Q8K1Y6, Q9ERC2	Gene names	Cstf2
Domain Architecture	No domain graphic available
Description	Cleavage stimulation factor 64 kDa subunit (CSTF 64 kDa subunit) (CF-1 64 kDa subunit) (CstF-64).

ZN541_HUMAN
NC score	0.036279 (rank : 857)	θ value	8.99809 (rank : 871)
Query Neighborhood Hits	872	Target Neighborhood Hits	203	Shared Neighborhood Hits	69
SwissProt Accessions	Q9H0D2, Q8NDK8	Gene names	ZNF541
Domain Architecture	No domain graphic available
Description	Zinc finger protein 541.

NOTC2_MOUSE
NC score	0.036188 (rank : 858)	θ value	0.00665767 (rank : 183)
Query Neighborhood Hits	872	Target Neighborhood Hits	1069	Shared Neighborhood Hits	154
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

REPS1_MOUSE
NC score	0.035717 (rank : 859)	θ value	5.27518 (rank : 735)
Query Neighborhood Hits	872	Target Neighborhood Hits	204	Shared Neighborhood Hits	41
SwissProt Accessions	O54916, Q8C9J9, Q99LR8	Gene names	Reps1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

SF3B2_HUMAN
NC score	0.035676 (rank : 860)	θ value	2.36792 (rank : 617)
Query Neighborhood Hits	872	Target Neighborhood Hits	157	Shared Neighborhood Hits	34
SwissProt Accessions	Q13435	Gene names	SF3B2, SAP145
Domain Architecture
Description	Splicing factor 3B subunit 2 (Spliceosome-associated protein 145) (SAP 145) (SF3b150) (Pre-mRNA-splicing factor SF3b 145 kDa subunit).

CAC1A_HUMAN
NC score	0.035620 (rank : 861)	θ value	0.0431538 (rank : 258)
Query Neighborhood Hits	872	Target Neighborhood Hits	387	Shared Neighborhood Hits	129
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CASZ1_HUMAN
NC score	0.035476 (rank : 862)	θ value	0.0252991 (rank : 236)
Query Neighborhood Hits	872	Target Neighborhood Hits	473	Shared Neighborhood Hits	38
SwissProt Accessions	Q86V15, Q5T9S1, Q8WX49, Q8WX50, Q9BT16, Q9NXC6	Gene names	CASZ1, CST, ZNF693
Domain Architecture	No domain graphic available
Description	Castor homolog 1 zinc finger protein (Castor-related protein) (Zinc finger protein 693).

SPR2F_MOUSE
NC score	0.035437 (rank : 863)	θ value	1.06291 (rank : 514)
Query Neighborhood Hits	872	Target Neighborhood Hits	43	Shared Neighborhood Hits	9
SwissProt Accessions	O70557	Gene names	Sprr2f
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F.

PO6F1_MOUSE
NC score	0.035218 (rank : 864)	θ value	6.88961 (rank : 785)
Query Neighborhood Hits	872	Target Neighborhood Hits	581	Shared Neighborhood Hits	131
SwissProt Accessions	Q07916, Q91XK3	Gene names	Pou6f1, Emb
Domain Architecture
Description	POU domain, class 6, transcription factor 1 (Octamer-binding transcription factor EMB) (Transcription regulatory protein MCP-1).

ATBF1_MOUSE
NC score	0.034256 (rank : 865)	θ value	0.21417 (rank : 358)
Query Neighborhood Hits	872	Target Neighborhood Hits	1841	Shared Neighborhood Hits	199
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

SIN3A_HUMAN
NC score	0.034092 (rank : 866)	θ value	1.38821 (rank : 548)
Query Neighborhood Hits	872	Target Neighborhood Hits	180	Shared Neighborhood Hits	66
SwissProt Accessions	Q96ST3, Q8N8N4, Q8NC83, Q8WV18, Q96L98, Q9UFQ1	Gene names	SIN3A
Domain Architecture
Description	Paired amphipathic helix protein Sin3a (Transcriptional corepressor Sin3a) (Histone deacetylase complex subunit Sin3a).

IRX5_HUMAN
NC score	0.033998 (rank : 867)	θ value	4.03905 (rank : 684)
Query Neighborhood Hits	872	Target Neighborhood Hits	362	Shared Neighborhood Hits	80
SwissProt Accessions	P78411, P78416, Q7Z2E1	Gene names	IRX5, IRX2A, IRXB2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-5 (Iroquois homeobox protein 5) (Homeodomain protein IRXB2) (IRX-2A).

PLXB1_HUMAN
NC score	0.033941 (rank : 868)	θ value	5.27518 (rank : 731)
Query Neighborhood Hits	872	Target Neighborhood Hits	360	Shared Neighborhood Hits	126
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

HNRL1_MOUSE
NC score	0.033902 (rank : 869)	θ value	1.81305 (rank : 568)
Query Neighborhood Hits	872	Target Neighborhood Hits	200	Shared Neighborhood Hits	60
SwissProt Accessions	Q8VDM6, Q3U201, Q3UPB0, Q6AZA7, Q8BY45, Q8K365	Gene names	Hnrpul1
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1.

DVL2_MOUSE
NC score	0.033599 (rank : 870)	θ value	8.99809 (rank : 820)
Query Neighborhood Hits	872	Target Neighborhood Hits	233	Shared Neighborhood Hits	56
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

NCTR2_HUMAN
NC score	0.033481 (rank : 871)	θ value	1.06291 (rank : 505)
Query Neighborhood Hits	872	Target Neighborhood Hits	99	Shared Neighborhood Hits	30
SwissProt Accessions	O95944, Q9H562, Q9H563, Q9H564, Q9UMT1, Q9UMT2	Gene names	NCR2, LY95
Domain Architecture
Description	Natural cytotoxicity triggering receptor 2 precursor (Natural killer cell p44-related protein) (NKp44) (NK-p44) (NK cell-activating receptor) (Lymphocyte antigen 95 homolog) (CD336 antigen).

FOG1_HUMAN
NC score	0.033003 (rank : 872)	θ value	0.000158464 (rank : 92)
Query Neighborhood Hits	872	Target Neighborhood Hits	981	Shared Neighborhood Hits	146
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

COA2_HUMAN
NC score	0.032954 (rank : 873)	θ value	1.06291 (rank : 488)
Query Neighborhood Hits	872	Target Neighborhood Hits	184	Shared Neighborhood Hits	54
SwissProt Accessions	O00763, Q16852	Gene names	ACACB, ACC2, ACCB
Domain Architecture
Description	Acetyl-CoA carboxylase 2 (EC 6.4.1.2) (ACC-beta) [Includes: Biotin carboxylase (EC 6.3.4.14)].

MAST4_HUMAN
NC score	0.032807 (rank : 874)	θ value	4.03905 (rank : 685)
Query Neighborhood Hits	872	Target Neighborhood Hits	1804	Shared Neighborhood Hits	305
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

LNP_MOUSE
NC score	0.032726 (rank : 875)	θ value	3.0926 (rank : 652)
Query Neighborhood Hits	872	Target Neighborhood Hits	83	Shared Neighborhood Hits	25
SwissProt Accessions	Q7TQ95, Q69ZC5, Q6PAQ1, Q6PEN8	Gene names	Lnp, Kiaa1715, Uln
Domain Architecture	No domain graphic available
Description	Protein lunapark (Protein ulnaless).

IRX5_MOUSE
NC score	0.032655 (rank : 876)	θ value	0.47712 (rank : 413)
Query Neighborhood Hits	872	Target Neighborhood Hits	324	Shared Neighborhood Hits	61
SwissProt Accessions	Q9JKQ4, Q80WV4, Q9JLL5	Gene names	Irx5, Irxb2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-5 (Iroquois homeobox protein 5) (Homeodomain protein IRXB2).

SMCA2_HUMAN
NC score	0.032615 (rank : 877)	θ value	0.279714 (rank : 384)
Query Neighborhood Hits	872	Target Neighborhood Hits	503	Shared Neighborhood Hits	96
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

RP3A_HUMAN
NC score	0.032613 (rank : 878)	θ value	0.813845 (rank : 474)
Query Neighborhood Hits	872	Target Neighborhood Hits	305	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

LEG3_HUMAN
NC score	0.032555 (rank : 879)	θ value	2.36792 (rank : 602)
Query Neighborhood Hits	872	Target Neighborhood Hits	124	Shared Neighborhood Hits	51
SwissProt Accessions	P17931, Q16005, Q96J47	Gene names	LGALS3, MAC2
Domain Architecture
Description	Galectin-3 (Galactose-specific lectin 3) (Mac-2 antigen) (IgE-binding protein) (35 kDa lectin) (Carbohydrate-binding protein 35) (CBP 35) (Laminin-binding protein) (Lectin L-29) (L-31) (Galactoside-binding protein) (GALBP).

WNK2_HUMAN
NC score	0.032474 (rank : 880)	θ value	0.00228821 (rank : 148)
Query Neighborhood Hits	872	Target Neighborhood Hits	1407	Shared Neighborhood Hits	246
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

NCOR1_HUMAN
NC score	0.032302 (rank : 881)	θ value	8.99809 (rank : 848)
Query Neighborhood Hits	872	Target Neighborhood Hits	577	Shared Neighborhood Hits	95
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

DBP_HUMAN
NC score	0.031989 (rank : 882)	θ value	0.279714 (rank : 376)
Query Neighborhood Hits	872	Target Neighborhood Hits	136	Shared Neighborhood Hits	36
SwissProt Accessions	Q10586	Gene names	DBP
Domain Architecture
Description	D site-binding protein (Albumin D box-binding protein) (Albumin D- element-binding protein) (TAXREB302).

GGA3_MOUSE
NC score	0.031926 (rank : 883)	θ value	5.27518 (rank : 723)
Query Neighborhood Hits	872	Target Neighborhood Hits	148	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BMI3, Q80U71	Gene names	Gga3, Kiaa0154
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

RBBP6_HUMAN
NC score	0.031809 (rank : 884)	θ value	3.0926 (rank : 658)
Query Neighborhood Hits	872	Target Neighborhood Hits	1135	Shared Neighborhood Hits	107
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

MEF2C_HUMAN
NC score	0.031677 (rank : 885)	θ value	0.62314 (rank : 439)
Query Neighborhood Hits	872	Target Neighborhood Hits	90	Shared Neighborhood Hits	31
SwissProt Accessions	Q06413	Gene names	MEF2C
Domain Architecture
Description	Myocyte-specific enhancer factor 2C.

LPP_MOUSE
NC score	0.031660 (rank : 886)	θ value	0.62314 (rank : 438)
Query Neighborhood Hits	872	Target Neighborhood Hits	247	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BFW7, Q5U407, Q8BHI1, Q8BKI0, Q8BKN2, Q8BLF4, Q8BLG3, Q8C101	Gene names	Lpp
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner homolog.

RBBP6_MOUSE
NC score	0.031535 (rank : 887)	θ value	3.0926 (rank : 659)
Query Neighborhood Hits	872	Target Neighborhood Hits	1014	Shared Neighborhood Hits	105
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

CMTA2_HUMAN
NC score	0.030556 (rank : 888)	θ value	5.27518 (rank : 709)
Query Neighborhood Hits	872	Target Neighborhood Hits	199	Shared Neighborhood Hits	37
SwissProt Accessions	O94983, Q7Z6M8, Q8N3V0, Q8NDG4, Q96G17	Gene names	CAMTA2, KIAA0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

SEM6B_MOUSE
NC score	0.030403 (rank : 889)	θ value	1.38821 (rank : 547)
Query Neighborhood Hits	872	Target Neighborhood Hits	200	Shared Neighborhood Hits	95
SwissProt Accessions	O54951	Gene names	Sema6b, Seman
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin VIB) (Sema VIB) (Semaphorin N) (Sema N).

CUTL2_HUMAN
NC score	0.030100 (rank : 890)	θ value	6.88961 (rank : 764)
Query Neighborhood Hits	872	Target Neighborhood Hits	906	Shared Neighborhood Hits	139
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

SIN3A_MOUSE
NC score	0.029785 (rank : 891)	θ value	5.27518 (rank : 739)
Query Neighborhood Hits	872	Target Neighborhood Hits	169	Shared Neighborhood Hits	56
SwissProt Accessions	Q60520, Q60820, Q62139, Q62140, Q7TPU8, Q7TSZ2	Gene names	Sin3a
Domain Architecture
Description	Paired amphipathic helix protein Sin3a (Transcriptional corepressor Sin3a) (Histone deacetylase complex subunit Sin3a).

K0329_HUMAN
NC score	0.029713 (rank : 892)	θ value	1.06291 (rank : 500)
Query Neighborhood Hits	872	Target Neighborhood Hits	85	Shared Neighborhood Hits	11
SwissProt Accessions	O15040, Q9UEG6	Gene names	KIAA0329, KIAA0297
Domain Architecture
Description	Protein KIAA0329/KIAA0297.

HXA3_MOUSE
NC score	0.029634 (rank : 893)	θ value	0.279714 (rank : 379)
Query Neighborhood Hits	872	Target Neighborhood Hits	558	Shared Neighborhood Hits	111
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

LNP_HUMAN
NC score	0.029555 (rank : 894)	θ value	1.06291 (rank : 501)
Query Neighborhood Hits	872	Target Neighborhood Hits	62	Shared Neighborhood Hits	19
SwissProt Accessions	Q9C0E8, Q2M2V8, Q2YD99, Q658W8, Q8N5V9, Q96MS5	Gene names	LNP, KIAA1715
Domain Architecture	No domain graphic available
Description	Protein lunapark.

WHRN_HUMAN
NC score	0.029310 (rank : 895)	θ value	1.38821 (rank : 553)
Query Neighborhood Hits	872	Target Neighborhood Hits	325	Shared Neighborhood Hits	72
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

FOXJ2_HUMAN
NC score	0.029164 (rank : 896)	θ value	6.88961 (rank : 771)
Query Neighborhood Hits	872	Target Neighborhood Hits	239	Shared Neighborhood Hits	88
SwissProt Accessions	Q9P0K8, Q96PS9, Q9NSN5	Gene names	FOXJ2, FHX
Domain Architecture
Description	Forkhead box protein J2 (Fork head homologous X).

DVL1L_HUMAN
NC score	0.029120 (rank : 897)	θ value	0.62314 (rank : 431)
Query Neighborhood Hits	872	Target Neighborhood Hits	146	Shared Neighborhood Hits	17
SwissProt Accessions	P54792	Gene names	DVL1L1, DVL, DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled- 1-like) (DSH homolog 1-like).

NKX61_HUMAN
NC score	0.028966 (rank : 898)	θ value	0.125558 (rank : 322)
Query Neighborhood Hits	872	Target Neighborhood Hits	431	Shared Neighborhood Hits	60
SwissProt Accessions	P78426	Gene names	NKX6-1, NKX6A
Domain Architecture
Description	Homeobox protein Nkx-6.1.

ZN318_MOUSE
NC score	0.028634 (rank : 899)	θ value	5.27518 (rank : 748)
Query Neighborhood Hits	872	Target Neighborhood Hits	642	Shared Neighborhood Hits	84
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

GRIN2_HUMAN
NC score	0.028546 (rank : 900)	θ value	1.81305 (rank : 567)
Query Neighborhood Hits	872	Target Neighborhood Hits	53	Shared Neighborhood Hits	15
SwissProt Accessions	O60269, Q5SVF0	Gene names	GPRIN2, KIAA0514
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 2 (GRIN2).

RAVR1_MOUSE
NC score	0.028543 (rank : 901)	θ value	1.38821 (rank : 543)
Query Neighborhood Hits	872	Target Neighborhood Hits	179	Shared Neighborhood Hits	31
SwissProt Accessions	Q9CW46, Q5DTT6, Q811K0, Q8C3Z1, Q8CA14	Gene names	Raver1, Kiaa1978
Domain Architecture	No domain graphic available
Description	Ribonucleoprotein PTB-binding 1 (Protein raver-1).

C2TA_HUMAN
NC score	0.028525 (rank : 902)	θ value	6.88961 (rank : 757)
Query Neighborhood Hits	872	Target Neighborhood Hits	190	Shared Neighborhood Hits	62
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

NKX61_MOUSE
NC score	0.028504 (rank : 903)	θ value	0.163984 (rank : 349)
Query Neighborhood Hits	872	Target Neighborhood Hits	439	Shared Neighborhood Hits	63
SwissProt Accessions	Q99MA9, Q9ERQ7	Gene names	Nkx6-1, Nkx6.1, Nkx6a
Domain Architecture
Description	Homeobox protein Nkx-6.1.

SYFB_HUMAN
NC score	0.028499 (rank : 904)	θ value	1.38821 (rank : 551)
Query Neighborhood Hits	872	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NSD9, O95708, Q9NZZ6	Gene names	FARSLB, FARSB, FRSB
Domain Architecture
Description	Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) (Phenylalanine-- tRNA ligase beta chain) (PheRS).

RXRB_HUMAN
NC score	0.028471 (rank : 905)	θ value	0.00175202 (rank : 140)
Query Neighborhood Hits	872	Target Neighborhood Hits	280	Shared Neighborhood Hits	83
SwissProt Accessions	P28702, P28703	Gene names	RXRB, NR2B2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta).

DVL1_HUMAN
NC score	0.028443 (rank : 906)	θ value	1.06291 (rank : 495)
Query Neighborhood Hits	872	Target Neighborhood Hits	158	Shared Neighborhood Hits	22
SwissProt Accessions	O14640	Gene names	DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

MEF2C_MOUSE
NC score	0.028336 (rank : 907)	θ value	3.0926 (rank : 654)
Query Neighborhood Hits	872	Target Neighborhood Hits	92	Shared Neighborhood Hits	31
SwissProt Accessions	Q8CFN5, Q8R0H1, Q9D7L0, Q9QW20	Gene names	Mef2c
Domain Architecture	No domain graphic available
Description	Myocyte-specific enhancer factor 2C.

LRC56_HUMAN
NC score	0.028265 (rank : 908)	θ value	0.813845 (rank : 463)
Query Neighborhood Hits	872	Target Neighborhood Hits	165	Shared Neighborhood Hits	36
SwissProt Accessions	Q8IYG6, Q8N3Q4	Gene names	LRRC56
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 56.

ZDHC1_HUMAN
NC score	0.028258 (rank : 909)	θ value	0.163984 (rank : 356)
Query Neighborhood Hits	872	Target Neighborhood Hits	84	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WTX9, O15461	Gene names	ZDHHC1, C16orf1, ZNF377
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC1 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 1) (DHHC-1) (Zinc finger protein 377) (DHHC- domain-containing cysteine-rich protein 1).

CND2_HUMAN
NC score	0.027268 (rank : 910)	θ value	1.38821 (rank : 526)
Query Neighborhood Hits	872	Target Neighborhood Hits	26	Shared Neighborhood Hits	9
SwissProt Accessions	Q15003, Q8TB87	Gene names	NCAPH, BRRN, BRRN1, CAPH, KIAA0074
Domain Architecture
Description	Condensin complex subunit 2 (Non-SMC condensin I complex subunit H) (Barren homolog protein 1) (Chromosome-associated protein H) (hCAP-H) (XCAP-H homolog).

CDX1_MOUSE
NC score	0.027228 (rank : 911)	θ value	0.0113563 (rank : 198)
Query Neighborhood Hits	872	Target Neighborhood Hits	379	Shared Neighborhood Hits	55
SwissProt Accessions	P18111, Q8VCF7	Gene names	Cdx1, Cdx-1
Domain Architecture
Description	Homeobox protein CDX-1 (Caudal-type homeobox protein 1).

SCAP_HUMAN
NC score	0.027099 (rank : 912)	θ value	8.99809 (rank : 860)
Query Neighborhood Hits	872	Target Neighborhood Hits	368	Shared Neighborhood Hits	92
SwissProt Accessions	Q12770, Q8N2E0, Q8WUA1	Gene names	SCAP, KIAA0199
Domain Architecture
Description	Sterol regulatory element-binding protein cleavage-activating protein (SREBP cleavage-activating protein) (SCAP).

DVL1_MOUSE
NC score	0.027053 (rank : 913)	θ value	6.88961 (rank : 768)
Query Neighborhood Hits	872	Target Neighborhood Hits	146	Shared Neighborhood Hits	15
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

USH1C_MOUSE
NC score	0.026927 (rank : 914)	θ value	6.88961 (rank : 799)
Query Neighborhood Hits	872	Target Neighborhood Hits	557	Shared Neighborhood Hits	83
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

GGA3_HUMAN
NC score	0.026708 (rank : 915)	θ value	5.27518 (rank : 722)
Query Neighborhood Hits	872	Target Neighborhood Hits	127	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NZ52, Q15017, Q6IS16, Q9UJY3	Gene names	GGA3, KIAA0154
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

TULP4_MOUSE
NC score	0.026702 (rank : 916)	θ value	3.0926 (rank : 666)
Query Neighborhood Hits	872	Target Neighborhood Hits	247	Shared Neighborhood Hits	62
SwissProt Accessions	Q9JIL5, Q8CA75, Q922C2	Gene names	Tulp4, Tusp
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

TIF1G_MOUSE
NC score	0.026641 (rank : 917)	θ value	4.03905 (rank : 703)
Query Neighborhood Hits	872	Target Neighborhood Hits	498	Shared Neighborhood Hits	94
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

SEN54_HUMAN
NC score	0.026634 (rank : 918)	θ value	0.62314 (rank : 446)
Query Neighborhood Hits	872	Target Neighborhood Hits	23	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z6J9, Q86WV3, Q86XE4, Q8N9H2	Gene names	TSEN54, SEN54
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen54 (tRNA-intron endonuclease Sen54) (HsSen54).

CDX1_HUMAN
NC score	0.026502 (rank : 919)	θ value	0.00869519 (rank : 186)
Query Neighborhood Hits	872	Target Neighborhood Hits	382	Shared Neighborhood Hits	47
SwissProt Accessions	P47902, Q4VAU4, Q9NYK8	Gene names	CDX1
Domain Architecture
Description	Homeobox protein CDX-1 (Caudal-type homeobox protein 1).

HXA3_HUMAN
NC score	0.026370 (rank : 920)	θ value	4.03905 (rank : 682)
Query Neighborhood Hits	872	Target Neighborhood Hits	535	Shared Neighborhood Hits	109
SwissProt Accessions	O43365	Gene names	HOXA3, HOX1E
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1E).

IRX3_HUMAN
NC score	0.026362 (rank : 921)	θ value	2.36792 (rank : 600)
Query Neighborhood Hits	872	Target Neighborhood Hits	342	Shared Neighborhood Hits	61
SwissProt Accessions	P78415, Q7Z4A4, Q7Z4A5, Q8IVC6	Gene names	IRX3, IRXB1
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-3 (Iroquois homeobox protein 3) (Homeodomain protein IRXB1).

BAG4_HUMAN
NC score	0.026171 (rank : 922)	θ value	1.81305 (rank : 557)
Query Neighborhood Hits	872	Target Neighborhood Hits	96	Shared Neighborhood Hits	23
SwissProt Accessions	O95429, O95818	Gene names	BAG4, SODD
Domain Architecture
Description	BAG family molecular chaperone regulator 4 (BCL2-associated athanogene 4) (BAG-4) (Silencer of death domains).

CTTB2_HUMAN
NC score	0.025959 (rank : 923)	θ value	3.0926 (rank : 636)
Query Neighborhood Hits	872	Target Neighborhood Hits	1061	Shared Neighborhood Hits	90
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

TTP_MOUSE
NC score	0.025668 (rank : 924)	θ value	0.47712 (rank : 423)
Query Neighborhood Hits	872	Target Neighborhood Hits	75	Shared Neighborhood Hits	11
SwissProt Accessions	P22893, P11520	Gene names	Zfp36, Tis11, Tis11a
Domain Architecture
Description	Tristetraproline (TTP) (Zinc finger protein 36) (Zfp-36) (TIS11A protein) (TIS11) (Growth factor-inducible nuclear protein NUP475) (TPA-induced sequence 11).

ZC3H3_MOUSE
NC score	0.025666 (rank : 925)	θ value	1.06291 (rank : 521)
Query Neighborhood Hits	872	Target Neighborhood Hits	188	Shared Neighborhood Hits	51
SwissProt Accessions	Q8CHP0, Q80X78	Gene names	Zc3h3, Kiaa0150, Zc3hdc3, Zfp623
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

ZN414_HUMAN
NC score	0.025546 (rank : 926)	θ value	8.99809 (rank : 870)
Query Neighborhood Hits	872	Target Neighborhood Hits	548	Shared Neighborhood Hits	64
SwissProt Accessions	Q96IQ9	Gene names	ZNF414
Domain Architecture	No domain graphic available
Description	Zinc finger protein 414.

LOXL1_MOUSE
NC score	0.025531 (rank : 927)	θ value	0.47712 (rank : 414)
Query Neighborhood Hits	872	Target Neighborhood Hits	58	Shared Neighborhood Hits	28
SwissProt Accessions	P97873, Q91ZY4, Q99KX3	Gene names	Loxl1, Lox2, Loxl
Domain Architecture
Description	Lysyl oxidase homolog 1 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 1) (Lysyl oxidase 2).

SIX5_HUMAN
NC score	0.025407 (rank : 928)	θ value	0.813845 (rank : 476)
Query Neighborhood Hits	872	Target Neighborhood Hits	386	Shared Neighborhood Hits	63
SwissProt Accessions	Q8N196	Gene names	SIX5, DMAHP
Domain Architecture	No domain graphic available
Description	Homeobox protein SIX5 (DM locus-associated homeodomain protein).

AKA11_HUMAN
NC score	0.025141 (rank : 929)	θ value	1.06291 (rank : 483)
Query Neighborhood Hits	872	Target Neighborhood Hits	57	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UKA4, O75124, Q9NUK7	Gene names	AKAP11, AKAP220, KIAA0629
Domain Architecture
Description	A-kinase anchor protein 11 (Protein kinase A-anchoring protein 11) (PRKA11) (A kinase anchor protein 220 kDa) (AKAP 220) (hAKAP220).

OBSCN_HUMAN
NC score	0.025035 (rank : 930)	θ value	0.279714 (rank : 381)
Query Neighborhood Hits	872	Target Neighborhood Hits	1931	Shared Neighborhood Hits	262
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

TM16H_HUMAN
NC score	0.025024 (rank : 931)	θ value	2.36792 (rank : 625)
Query Neighborhood Hits	872	Target Neighborhood Hits	139	Shared Neighborhood Hits	42
SwissProt Accessions	Q9HCE9	Gene names	TMEM16H, KIAA1623
Domain Architecture	No domain graphic available
Description	Transmembrane protein 16H.

DLG4_HUMAN
NC score	0.024688 (rank : 932)	θ value	2.36792 (rank : 593)
Query Neighborhood Hits	872	Target Neighborhood Hits	286	Shared Neighborhood Hits	71
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

ATBF1_HUMAN
NC score	0.024660 (rank : 933)	θ value	0.62314 (rank : 426)
Query Neighborhood Hits	872	Target Neighborhood Hits	1547	Shared Neighborhood Hits	154
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

DTX1_MOUSE
NC score	0.024536 (rank : 934)	θ value	1.38821 (rank : 532)
Query Neighborhood Hits	872	Target Neighborhood Hits	99	Shared Neighborhood Hits	35
SwissProt Accessions	Q61010, Q3TER5, Q8C2H2, Q9ER09	Gene names	Dtx1
Domain Architecture
Description	Protein deltex-1 (Deltex-1) (Deltex1) (mDTX1) (FXI-T1).

PTPRN_MOUSE
NC score	0.024089 (rank : 935)	θ value	6.88961 (rank : 787)
Query Neighborhood Hits	872	Target Neighborhood Hits	240	Shared Neighborhood Hits	82
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

SEZ6L_HUMAN
NC score	0.024074 (rank : 936)	θ value	5.27518 (rank : 737)
Query Neighborhood Hits	872	Target Neighborhood Hits	289	Shared Neighborhood Hits	80
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

SREC2_HUMAN
NC score	0.023957 (rank : 937)	θ value	3.0926 (rank : 662)
Query Neighborhood Hits	872	Target Neighborhood Hits	645	Shared Neighborhood Hits	92
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

NMDE3_HUMAN
NC score	0.023844 (rank : 938)	θ value	1.38821 (rank : 540)
Query Neighborhood Hits	872	Target Neighborhood Hits	110	Shared Neighborhood Hits	22
SwissProt Accessions	Q14957	Gene names	GRIN2C
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 3 precursor (N-methyl D- aspartate receptor subtype 2C) (NR2C) (NMDAR2C).

CAC1H_HUMAN
NC score	0.023788 (rank : 939)	θ value	1.81305 (rank : 558)
Query Neighborhood Hits	872	Target Neighborhood Hits	307	Shared Neighborhood Hits	81
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

NANO1_HUMAN
NC score	0.023753 (rank : 940)	θ value	0.62314 (rank : 441)
Query Neighborhood Hits	872	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WY41	Gene names	NANOS1, NOS1
Domain Architecture
Description	Nanos homolog 1 (NOS-1) (EC_Rep1a).

TRIP6_HUMAN
NC score	0.023356 (rank : 941)	θ value	3.0926 (rank : 665)
Query Neighborhood Hits	872	Target Neighborhood Hits	228	Shared Neighborhood Hits	48
SwissProt Accessions	Q15654, O15170, O15275, Q9BTB2, Q9UNT4	Gene names	TRIP6, OIP1
Domain Architecture
Description	Thyroid receptor-interacting protein 6 (TRIP6) (OPA-interacting protein 1) (Zyxin-related protein 1) (ZRP-1).

IRX3_MOUSE
NC score	0.023261 (rank : 942)	θ value	4.03905 (rank : 683)
Query Neighborhood Hits	872	Target Neighborhood Hits	303	Shared Neighborhood Hits	46
SwissProt Accessions	P81067	Gene names	Irx3, Irxb1
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-3 (Iroquois homeobox protein 3) (Homeodomain protein IRXB1).

DLG4_MOUSE
NC score	0.023021 (rank : 943)	θ value	2.36792 (rank : 594)
Query Neighborhood Hits	872	Target Neighborhood Hits	282	Shared Neighborhood Hits	69
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

FUBP3_HUMAN
NC score	0.022963 (rank : 944)	θ value	0.365318 (rank : 391)
Query Neighborhood Hits	872	Target Neighborhood Hits	68	Shared Neighborhood Hits	18
SwissProt Accessions	Q96I24, Q92946, Q9BVB6	Gene names	FUBP3
Domain Architecture
Description	Far upstream element-binding protein 3 (FUSE-binding protein 3).

FOXC2_HUMAN
NC score	0.022882 (rank : 945)	θ value	1.38821 (rank : 535)
Query Neighborhood Hits	872	Target Neighborhood Hits	236	Shared Neighborhood Hits	71
SwissProt Accessions	Q99958	Gene names	FOXC2, FKHL14, MFH1
Domain Architecture
Description	Forkhead box protein C2 (Forkhead-related protein FKHL14) (Mesenchyme fork head protein 1) (MFH-1 protein) (Transcription factor FKH-14).

FOXC1_MOUSE
NC score	0.022862 (rank : 946)	θ value	2.36792 (rank : 599)
Query Neighborhood Hits	872	Target Neighborhood Hits	218	Shared Neighborhood Hits	56
SwissProt Accessions	Q61572, O88409, Q61582	Gene names	Foxc1, Fkh1, Fkhl7, Freac3, Mf1
Domain Architecture
Description	Forkhead box protein C1 (Forkhead-related protein FKHL7) (Forkhead- related transcription factor 3) (FREAC-3) (Transcription factor FKH-1) (Mesoderm/mesenchyme forkhead 1) (MF-1).

DEND_MOUSE
NC score	0.022849 (rank : 947)	θ value	8.99809 (rank : 817)
Query Neighborhood Hits	872	Target Neighborhood Hits	75	Shared Neighborhood Hits	32
SwissProt Accessions	Q80TS7	Gene names	Ddn, Kiaa0749
Domain Architecture	No domain graphic available
Description	Dendrin.

RNF38_HUMAN
NC score	0.022788 (rank : 948)	θ value	0.279714 (rank : 383)
Query Neighborhood Hits	872	Target Neighborhood Hits	155	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H0F5, Q8N0Y0	Gene names	RNF38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

ICAL_HUMAN
NC score	0.022372 (rank : 949)	θ value	8.99809 (rank : 829)
Query Neighborhood Hits	872	Target Neighborhood Hits	275	Shared Neighborhood Hits	40
SwissProt Accessions	P20810, O95360, Q96D08, Q9H1Z5	Gene names	CAST
Domain Architecture
Description	Calpastatin (Calpain inhibitor) (Sperm BS-17 component).

ANR40_HUMAN
NC score	0.022353 (rank : 950)	θ value	4.03905 (rank : 671)
Query Neighborhood Hits	872	Target Neighborhood Hits	224	Shared Neighborhood Hits	34
SwissProt Accessions	Q6AI12, Q96E32	Gene names	ANKRD40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

LYN_HUMAN
NC score	0.022299 (rank : 951)	θ value	8.99809 (rank : 841)
Query Neighborhood Hits	872	Target Neighborhood Hits	1022	Shared Neighborhood Hits	130
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

PEF1_HUMAN
NC score	0.022279 (rank : 952)	θ value	0.47712 (rank : 417)
Query Neighborhood Hits	872	Target Neighborhood Hits	135	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UBV8	Gene names	PEF1, ABP32
Domain Architecture	No domain graphic available
Description	Peflin (PEF protein with a long N-terminal hydrophobic domain) (Penta- EF hand domain-containing protein 1).

LSD1_MOUSE
NC score	0.022095 (rank : 953)	θ value	6.88961 (rank : 780)
Query Neighborhood Hits	872	Target Neighborhood Hits	224	Shared Neighborhood Hits	28
SwissProt Accessions	Q6ZQ88, Q6PB53, Q8VEA1	Gene names	Aof2, Kiaa0601, Lsd1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

LYN_MOUSE
NC score	0.022082 (rank : 954)	θ value	6.88961 (rank : 781)
Query Neighborhood Hits	872	Target Neighborhood Hits	1023	Shared Neighborhood Hits	127
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

HME1_MOUSE
NC score	0.021857 (rank : 955)	θ value	0.163984 (rank : 341)
Query Neighborhood Hits	872	Target Neighborhood Hits	397	Shared Neighborhood Hits	55
SwissProt Accessions	P09065	Gene names	En1, En-1
Domain Architecture
Description	Homeobox protein engrailed-1 (Mo-En-1).

CRX_HUMAN
NC score	0.021845 (rank : 956)	θ value	0.0431538 (rank : 260)
Query Neighborhood Hits	872	Target Neighborhood Hits	360	Shared Neighborhood Hits	38
SwissProt Accessions	O43186	Gene names	CRX, CORD2
Domain Architecture
Description	Cone-rod homeobox protein.

AFF2_HUMAN
NC score	0.021844 (rank : 957)	θ value	6.88961 (rank : 752)
Query Neighborhood Hits	872	Target Neighborhood Hits	218	Shared Neighborhood Hits	53
SwissProt Accessions	P51816, O43786, O60215, P78407, Q13521, Q14323, Q9UNA5	Gene names	AFF2, FMR2, OX19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation 2 protein) (Protein FMR-2) (FMR2P) (Protein Ox19) (Fragile X E mental retardation syndrome protein).

RX_MOUSE
NC score	0.021772 (rank : 958)	θ value	0.62314 (rank : 445)
Query Neighborhood Hits	872	Target Neighborhood Hits	429	Shared Neighborhood Hits	62
SwissProt Accessions	O35602, O08748	Gene names	Rax, Rx
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

RGDSR_HUMAN
NC score	0.021683 (rank : 959)	θ value	8.99809 (rank : 856)
Query Neighborhood Hits	872	Target Neighborhood Hits	63	Shared Neighborhood Hits	26
SwissProt Accessions	Q8IZJ4	Gene names	RGR
Domain Architecture
Description	Ral-GDS-related protein (hRGR).

FBLI1_HUMAN
NC score	0.021675 (rank : 960)	θ value	1.06291 (rank : 497)
Query Neighborhood Hits	872	Target Neighborhood Hits	200	Shared Neighborhood Hits	32
SwissProt Accessions	Q8WUP2, Q5VVE0, Q5VVE1, Q8IX23, Q96T00, Q9UFD6	Gene names	FBLIM1, FBLP1
Domain Architecture
Description	Filamin-binding LIM protein 1 (Filamin-binding LIM protein 1) (FBLP-1) (Mitogen-inducible 2-interacting protein) (MIG2-interacting protein) (Migfilin).

CC040_HUMAN
NC score	0.021624 (rank : 961)	θ value	3.0926 (rank : 632)
Query Neighborhood Hits	872	Target Neighborhood Hits	23	Shared Neighborhood Hits	7
SwissProt Accessions	Q6UXB0, Q8TA84	Gene names	C3orf40
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf40 precursor.

KCNH2_MOUSE
NC score	0.021532 (rank : 962)	θ value	0.365318 (rank : 392)
Query Neighborhood Hits	872	Target Neighborhood Hits	165	Shared Neighborhood Hits	33
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

FOXP4_HUMAN
NC score	0.021370 (rank : 963)	θ value	6.88961 (rank : 772)
Query Neighborhood Hits	872	Target Neighborhood Hits	246	Shared Neighborhood Hits	68
SwissProt Accessions	Q8IVH2, Q96E19	Gene names	FOXP4, FKHLA
Domain Architecture
Description	Forkhead box protein P4 (Fork head-related protein-like A).

FBLI1_MOUSE
NC score	0.021297 (rank : 964)	θ value	3.0926 (rank : 641)
Query Neighborhood Hits	872	Target Neighborhood Hits	228	Shared Neighborhood Hits	38
SwissProt Accessions	Q71FD7, Q99J35	Gene names	Fblim1, Cal
Domain Architecture	No domain graphic available
Description	Filamin-binding LIM protein 1 (CSX-associated LIM).

NOTC3_MOUSE
NC score	0.021293 (rank : 965)	θ value	0.00869519 (rank : 189)
Query Neighborhood Hits	872	Target Neighborhood Hits	975	Shared Neighborhood Hits	87
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

ATF7_HUMAN
NC score	0.021013 (rank : 966)	θ value	6.88961 (rank : 755)
Query Neighborhood Hits	872	Target Neighborhood Hits	333	Shared Neighborhood Hits	60
SwissProt Accessions	P17544, Q13814	Gene names	ATF7, ATFA
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

RGP1_HUMAN
NC score	0.020919 (rank : 967)	θ value	1.38821 (rank : 545)
Query Neighborhood Hits	872	Target Neighborhood Hits	124	Shared Neighborhood Hits	9
SwissProt Accessions	P46060	Gene names	RANGAP1
Domain Architecture
Description	Ran GTPase-activating protein 1.

SYFB_MOUSE
NC score	0.020824 (rank : 968)	θ value	5.27518 (rank : 741)
Query Neighborhood Hits	872	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WUA2	Gene names	Farslb, Farsb, Farsl, Frsb
Domain Architecture
Description	Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) (Phenylalanine-- tRNA ligase beta chain) (PheRS).

RX_HUMAN
NC score	0.020592 (rank : 969)	θ value	0.163984 (rank : 353)
Query Neighborhood Hits	872	Target Neighborhood Hits	423	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y2V3	Gene names	RAX, RX
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

SPR2G_HUMAN
NC score	0.020580 (rank : 970)	θ value	5.27518 (rank : 740)
Query Neighborhood Hits	872	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BYE4	Gene names	SPRR2G
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G (SPR-2G).

RXRB_MOUSE
NC score	0.020317 (rank : 971)	θ value	0.163984 (rank : 352)
Query Neighborhood Hits	872	Target Neighborhood Hits	230	Shared Neighborhood Hits	68
SwissProt Accessions	P28704, P33243	Gene names	Rxrb, Nr2b2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta) (MHC class I regulatory element-binding protein H-2RIIBP).

GP152_MOUSE
NC score	0.020244 (rank : 972)	θ value	8.99809 (rank : 827)
Query Neighborhood Hits	872	Target Neighborhood Hits	607	Shared Neighborhood Hits	102
SwissProt Accessions	Q8BXS7	Gene names	Gpr152
Domain Architecture
Description	Probable G-protein coupled receptor 152.

ACK1_HUMAN
NC score	0.020241 (rank : 973)	θ value	3.0926 (rank : 628)
Query Neighborhood Hits	872	Target Neighborhood Hits	1140	Shared Neighborhood Hits	202
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

RNF38_MOUSE
NC score	0.020170 (rank : 974)	θ value	0.813845 (rank : 473)
Query Neighborhood Hits	872	Target Neighborhood Hits	153	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BI21, Q6P5B1	Gene names	Rnf38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

UBP31_HUMAN
NC score	0.019519 (rank : 975)	θ value	5.27518 (rank : 745)
Query Neighborhood Hits	872	Target Neighborhood Hits	293	Shared Neighborhood Hits	51
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

PHLPP_HUMAN
NC score	0.019376 (rank : 976)	θ value	2.36792 (rank : 612)
Query Neighborhood Hits	872	Target Neighborhood Hits	604	Shared Neighborhood Hits	122
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

DUS2L_HUMAN
NC score	0.019018 (rank : 977)	θ value	1.06291 (rank : 494)
Query Neighborhood Hits	872	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NX74, Q4H4D9	Gene names	DUS2L, DUS2
Domain Architecture	No domain graphic available
Description	tRNA-dihydrouridine synthase 2-like (EC 1.-.-.-) (hDUS2) (Up-regulated in lung cancer) (URLC8).

MICA1_HUMAN
NC score	0.018779 (rank : 978)	θ value	2.36792 (rank : 604)
Query Neighborhood Hits	872	Target Neighborhood Hits	279	Shared Neighborhood Hits	48
SwissProt Accessions	Q8TDZ2, Q7Z633, Q8IVS9, Q96G47, Q9H6X6, Q9H7I0, Q9HAA1, Q9UFF7	Gene names	MICAL1, MICAL, NICAL
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

DEND_HUMAN
NC score	0.018737 (rank : 979)	θ value	8.99809 (rank : 816)
Query Neighborhood Hits	872	Target Neighborhood Hits	88	Shared Neighborhood Hits	24
SwissProt Accessions	O94850	Gene names	DDN, KIAA0749
Domain Architecture	No domain graphic available
Description	Dendrin.

RFIP5_MOUSE
NC score	0.018520 (rank : 980)	θ value	4.03905 (rank : 692)
Query Neighborhood Hits	872	Target Neighborhood Hits	126	Shared Neighborhood Hits	31
SwissProt Accessions	Q8R361	Gene names	Rab11fip5, D6Ertd32e, Rip11
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 5 (Rab11-FIP5) (Rab11-interacting protein Rip11).

BAP1_HUMAN
NC score	0.018513 (rank : 981)	θ value	8.99809 (rank : 804)
Query Neighborhood Hits	872	Target Neighborhood Hits	106	Shared Neighborhood Hits	29
SwissProt Accessions	Q92560, Q6LEM0, Q7Z5E8	Gene names	BAP1, KIAA0272
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1- associated protein 1) (Cerebral protein 6).

HME1_HUMAN
NC score	0.018490 (rank : 982)	θ value	3.0926 (rank : 648)
Query Neighborhood Hits	872	Target Neighborhood Hits	384	Shared Neighborhood Hits	46
SwissProt Accessions	Q05925	Gene names	EN1
Domain Architecture
Description	Homeobox protein engrailed-1 (Hu-En-1).

DOK3_MOUSE
NC score	0.018335 (rank : 983)	θ value	1.06291 (rank : 493)
Query Neighborhood Hits	872	Target Neighborhood Hits	25	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QZK7	Gene names	Dok3, Dokl
Domain Architecture	No domain graphic available
Description	Docking protein 3 (Downstream of tyrosine kinase 3) (P62(dok)-like protein) (DOK-L).

SPR2E_MOUSE
NC score	0.018297 (rank : 984)	θ value	6.88961 (rank : 794)
Query Neighborhood Hits	872	Target Neighborhood Hits	45	Shared Neighborhood Hits	9
SwissProt Accessions	O70556	Gene names	Sprr2e
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E.

HHEX_MOUSE
NC score	0.018284 (rank : 985)	θ value	0.0961366 (rank : 309)
Query Neighborhood Hits	872	Target Neighborhood Hits	350	Shared Neighborhood Hits	31
SwissProt Accessions	P43120	Gene names	Hhex, Prhx
Domain Architecture
Description	Homeobox protein PRH (Hematopoietically expressed homeobox) (Homeobox protein HEX).

SREC2_MOUSE
NC score	0.018246 (rank : 986)	θ value	6.88961 (rank : 795)
Query Neighborhood Hits	872	Target Neighborhood Hits	605	Shared Neighborhood Hits	74
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

SEM6C_HUMAN
NC score	0.018141 (rank : 987)	θ value	0.0193708 (rank : 232)
Query Neighborhood Hits	872	Target Neighborhood Hits	117	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H3T2, Q5JR71, Q8WXT8, Q8WXT9, Q8WXU0, Q96JF8	Gene names	SEMA6C, KIAA1869, SEMAY
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

ACK1_MOUSE
NC score	0.018123 (rank : 988)	θ value	3.0926 (rank : 629)
Query Neighborhood Hits	872	Target Neighborhood Hits	1080	Shared Neighborhood Hits	186
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

DOK3_HUMAN
NC score	0.018047 (rank : 989)	θ value	5.27518 (rank : 715)
Query Neighborhood Hits	872	Target Neighborhood Hits	60	Shared Neighborhood Hits	18
SwissProt Accessions	Q7L591, Q8N864, Q9BQB3, Q9H666	Gene names	DOK3
Domain Architecture	No domain graphic available
Description	Docking protein 3 (Downstream of tyrosine kinase 3).

RGL2_HUMAN
NC score	0.017914 (rank : 990)	θ value	4.03905 (rank : 693)
Query Neighborhood Hits	872	Target Neighborhood Hits	45	Shared Neighborhood Hits	15
SwissProt Accessions	O15211, Q9Y3F3	Gene names	RGL2, RAB2L
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator-like 2 (RalGDS-like factor) (RAS-associated protein RAB2L).

MAGC3_HUMAN
NC score	0.017741 (rank : 991)	θ value	0.0736092 (rank : 296)
Query Neighborhood Hits	872	Target Neighborhood Hits	71	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TD91, Q5JZ43, Q9BZ80	Gene names	MAGEC3, HCA2
Domain Architecture
Description	Melanoma-associated antigen C3 (MAGE-C3 antigen) (Hepatocellular carcinoma-associated antigen 2).

CRX_MOUSE
NC score	0.017440 (rank : 992)	θ value	0.163984 (rank : 337)
Query Neighborhood Hits	872	Target Neighborhood Hits	359	Shared Neighborhood Hits	31
SwissProt Accessions	O54751	Gene names	Crx
Domain Architecture
Description	Cone-rod homeobox protein.

BAP1_MOUSE
NC score	0.017198 (rank : 993)	θ value	8.99809 (rank : 805)
Query Neighborhood Hits	872	Target Neighborhood Hits	118	Shared Neighborhood Hits	33
SwissProt Accessions	Q99PU7, Q6ZQE6	Gene names	Bap1, Kiaa0272
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1- associated protein 1) (Ubiquitin C-terminal hydrolase X4) (UCH-X4).

SYTL5_HUMAN
NC score	0.017183 (rank : 994)	θ value	1.06291 (rank : 518)
Query Neighborhood Hits	872	Target Neighborhood Hits	237	Shared Neighborhood Hits	28
SwissProt Accessions	Q8TDW5	Gene names	SYTL5, SLP5
Domain Architecture
Description	Synaptotagmin-like protein 5.

LOXL1_HUMAN
NC score	0.017018 (rank : 995)	θ value	3.0926 (rank : 653)
Query Neighborhood Hits	872	Target Neighborhood Hits	31	Shared Neighborhood Hits	9
SwissProt Accessions	Q08397, Q96BW7	Gene names	LOXL1, LOXL
Domain Architecture
Description	Lysyl oxidase homolog 1 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 1) (LOL).

WNK4_HUMAN
NC score	0.016176 (rank : 996)	θ value	0.0563607 (rank : 288)
Query Neighborhood Hits	872	Target Neighborhood Hits	1043	Shared Neighborhood Hits	127
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

USF2_MOUSE
NC score	0.016001 (rank : 997)	θ value	2.36792 (rank : 626)
Query Neighborhood Hits	872	Target Neighborhood Hits	173	Shared Neighborhood Hits	22
SwissProt Accessions	Q64705, Q3UIL2, Q8VE59	Gene names	Usf2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (Major late transcription factor 2).

NOTC4_MOUSE
NC score	0.015901 (rank : 998)	θ value	2.36792 (rank : 608)
Query Neighborhood Hits	872	Target Neighborhood Hits	872	Shared Neighborhood Hits	46
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

IP3KB_HUMAN
NC score	0.015605 (rank : 999)	θ value	8.99809 (rank : 832)
Query Neighborhood Hits	872	Target Neighborhood Hits	124	Shared Neighborhood Hits	42
SwissProt Accessions	P27987, Q5VWL9, Q5VWM0, Q96BZ2, Q96JS1, Q9UH47	Gene names	ITPKB
Domain Architecture
Description	Inositol-trisphosphate 3-kinase B (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase B) (IP3K B) (IP3 3-kinase B) (IP3K-B).

AF17_HUMAN
NC score	0.015397 (rank : 1000)	θ value	6.88961 (rank : 751)
Query Neighborhood Hits	872	Target Neighborhood Hits	230	Shared Neighborhood Hits	47
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

CTGE5_MOUSE
NC score	0.015144 (rank : 1001)	θ value	0.0736092 (rank : 291)
Query Neighborhood Hits	872	Target Neighborhood Hits	928	Shared Neighborhood Hits	69
SwissProt Accessions	Q8R311, Q8CIE3	Gene names	Ctage5, Mea6, Mgea6
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 5 homolog (cTAGE-5 protein) (Meningioma-expressed antigen 6).

HXA10_MOUSE
NC score	0.014982 (rank : 1002)	θ value	0.62314 (rank : 433)
Query Neighborhood Hits	872	Target Neighborhood Hits	365	Shared Neighborhood Hits	50
SwissProt Accessions	P31310, Q80Y22	Gene names	Hoxa10, Hox-1.8, Hoxa-10
Domain Architecture
Description	Homeobox protein Hox-A10 (Hox-1.8).

FOXJ3_HUMAN
NC score	0.014917 (rank : 1003)	θ value	5.27518 (rank : 717)
Query Neighborhood Hits	872	Target Neighborhood Hits	177	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UPW0, Q9NSS7	Gene names	FOXJ3, KIAA1041
Domain Architecture
Description	Forkhead box protein J3.

MATK_MOUSE
NC score	0.014860 (rank : 1004)	θ value	2.36792 (rank : 603)
Query Neighborhood Hits	872	Target Neighborhood Hits	952	Shared Neighborhood Hits	80
SwissProt Accessions	P41242, Q6LE90	Gene names	Matk, Ctk, Ntk
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK).

NLGN2_HUMAN
NC score	0.014794 (rank : 1005)	θ value	0.163984 (rank : 350)
Query Neighborhood Hits	872	Target Neighborhood Hits	55	Shared Neighborhood Hits	17
SwissProt Accessions	Q8NFZ4, Q9P2I1	Gene names	NLGN2, KIAA1366
Domain Architecture
Description	Neuroligin-2 precursor.

CHSS3_HUMAN
NC score	0.014739 (rank : 1006)	θ value	1.38821 (rank : 525)
Query Neighborhood Hits	872	Target Neighborhood Hits	97	Shared Neighborhood Hits	21
SwissProt Accessions	Q70JA7, Q76L22, Q86Y52	Gene names	CSS3, CHSY2
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate synthase 3 (EC 2.4.1.175) (Glucuronosyl-N- acetylgalactosaminyl-proteoglycan 4-beta-N- acetylgalactosaminyltransferase II) (Chondroitin synthase 2) (N- acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase II) (EC 2.4.1.226) (Chondroitin glucuronyltransferase II) (N- acetylgalactosaminyltransferase II) (Carbohydrate synthase 2).

SALL3_HUMAN
NC score	0.014671 (rank : 1007)	θ value	6.88961 (rank : 789)
Query Neighborhood Hits	872	Target Neighborhood Hits	1066	Shared Neighborhood Hits	165
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

TRML1_MOUSE
NC score	0.014598 (rank : 1008)	θ value	5.27518 (rank : 744)
Query Neighborhood Hits	872	Target Neighborhood Hits	44	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K558, Q9D3N6	Gene names	Treml1, Tlt1
Domain Architecture	No domain graphic available
Description	Trem-like transcript 1 protein precursor (TLT-1) (Triggering receptor expressed on myeloid cells-like protein 1).

ADA19_HUMAN
NC score	0.014575 (rank : 1009)	θ value	4.03905 (rank : 670)
Query Neighborhood Hits	872	Target Neighborhood Hits	381	Shared Neighborhood Hits	85
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

MATK_HUMAN
NC score	0.014213 (rank : 1010)	θ value	4.03905 (rank : 686)
Query Neighborhood Hits	872	Target Neighborhood Hits	954	Shared Neighborhood Hits	76
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

UBP43_HUMAN
NC score	0.014184 (rank : 1011)	θ value	1.81305 (rank : 586)
Query Neighborhood Hits	872	Target Neighborhood Hits	144	Shared Neighborhood Hits	33
SwissProt Accessions	Q70EL4, Q8N2C5, Q96DQ6	Gene names	USP43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

FOXB2_MOUSE
NC score	0.014164 (rank : 1012)	θ value	6.88961 (rank : 770)
Query Neighborhood Hits	872	Target Neighborhood Hits	139	Shared Neighborhood Hits	37
SwissProt Accessions	Q64733	Gene names	Foxb2, Fkh4
Domain Architecture
Description	Forkhead box protein B2 (Transcription factor FKH-4).

NLGN2_MOUSE
NC score	0.013975 (rank : 1013)	θ value	0.163984 (rank : 351)
Query Neighborhood Hits	872	Target Neighborhood Hits	49	Shared Neighborhood Hits	12
SwissProt Accessions	Q69ZK9, Q5F288	Gene names	Nlgn2, Kiaa1366
Domain Architecture	No domain graphic available
Description	Neuroligin-2 precursor.

CECR6_HUMAN
NC score	0.013942 (rank : 1014)	θ value	5.27518 (rank : 708)
Query Neighborhood Hits	872	Target Neighborhood Hits	23	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BXQ6	Gene names	CECR6
Domain Architecture	No domain graphic available
Description	Cat eye syndrome critical region protein 6.

TOM40_MOUSE
NC score	0.013811 (rank : 1015)	θ value	1.38821 (rank : 552)
Query Neighborhood Hits	872	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QYA2, Q9Z2N1	Gene names	Tomm40, Mom35, Tom40
Domain Architecture
Description	Probable mitochondrial import receptor subunit TOM40 homolog (Translocase of outer membrane 40 kDa subunit homolog).

IF4G3_HUMAN
NC score	0.013689 (rank : 1016)	θ value	6.88961 (rank : 777)
Query Neighborhood Hits	872	Target Neighborhood Hits	247	Shared Neighborhood Hits	36
SwissProt Accessions	O43432, Q15597, Q8NEN1	Gene names	EIF4G3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

DLX4_MOUSE
NC score	0.013627 (rank : 1017)	θ value	8.99809 (rank : 818)
Query Neighborhood Hits	872	Target Neighborhood Hits	352	Shared Neighborhood Hits	36
SwissProt Accessions	P70436, Q3UM51, Q8R4I3	Gene names	Dlx4, Dlx7
Domain Architecture
Description	Homeobox protein DLX-4 (DLX-7).

CEP41_HUMAN
NC score	0.013615 (rank : 1018)	θ value	8.99809 (rank : 810)
Query Neighborhood Hits	872	Target Neighborhood Hits	42	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BYV8, Q7Z496, Q86TM1, Q8NFU8, Q9H6A3, Q9NPV3	Gene names	TSGA14, CEP41
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 41 kDa (Cep41 protein) (Testis-specific gene A14 protein).

GPNMB_MOUSE
NC score	0.013327 (rank : 1019)	θ value	3.0926 (rank : 646)
Query Neighborhood Hits	872	Target Neighborhood Hits	40	Shared Neighborhood Hits	14
SwissProt Accessions	Q99P91, Q8BVV9, Q8BXL4, Q9QXA0	Gene names	Gpnmb, Dchil, Nmb
Domain Architecture	No domain graphic available
Description	Transmembrane glycoprotein NMB precursor (Dendritic cell-associated transmembrane protein) (DC-HIL).

NR4A3_MOUSE
NC score	0.013281 (rank : 1020)	θ value	0.0330416 (rank : 253)
Query Neighborhood Hits	872	Target Neighborhood Hits	127	Shared Neighborhood Hits	16
SwissProt Accessions	Q9QZB6, Q9QZB5	Gene names	Nr4a3, Tec
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Orphan nuclear receptor TEC) (Translocated in extraskeletal chondrosarcoma).

C1QR1_HUMAN
NC score	0.013269 (rank : 1021)	θ value	8.99809 (rank : 806)
Query Neighborhood Hits	872	Target Neighborhood Hits	493	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

ZNFX1_HUMAN
NC score	0.013175 (rank : 1022)	θ value	1.06291 (rank : 524)
Query Neighborhood Hits	872	Target Neighborhood Hits	308	Shared Neighborhood Hits	15
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

LRP5_MOUSE
NC score	0.013069 (rank : 1023)	θ value	0.163984 (rank : 346)
Query Neighborhood Hits	872	Target Neighborhood Hits	236	Shared Neighborhood Hits	19
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

SMN_HUMAN
NC score	0.012876 (rank : 1024)	θ value	6.88961 (rank : 790)
Query Neighborhood Hits	872	Target Neighborhood Hits	39	Shared Neighborhood Hits	8
SwissProt Accessions	Q16637, Q13119, Q96J51	Gene names	SMN1, SMN, SMNT
Domain Architecture
Description	Survival motor neuron protein (Component of gems 1) (Gemin-1).

FOXE3_MOUSE
NC score	0.012833 (rank : 1025)	θ value	1.81305 (rank : 565)
Query Neighborhood Hits	872	Target Neighborhood Hits	118	Shared Neighborhood Hits	26
SwissProt Accessions	Q9QY14	Gene names	Foxe3
Domain Architecture
Description	Forkhead box protein E3.

CCDC6_HUMAN
NC score	0.012802 (rank : 1026)	θ value	8.99809 (rank : 807)
Query Neighborhood Hits	872	Target Neighborhood Hits	723	Shared Neighborhood Hits	50
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

DOK2_HUMAN
NC score	0.012792 (rank : 1027)	θ value	6.88961 (rank : 767)
Query Neighborhood Hits	872	Target Neighborhood Hits	46	Shared Neighborhood Hits	12
SwissProt Accessions	O60496	Gene names	DOK2
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)).

FBN1_HUMAN
NC score	0.012758 (rank : 1028)	θ value	0.279714 (rank : 377)
Query Neighborhood Hits	872	Target Neighborhood Hits	557	Shared Neighborhood Hits	28
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

BAI2_HUMAN
NC score	0.012703 (rank : 1029)	θ value	0.163984 (rank : 332)
Query Neighborhood Hits	872	Target Neighborhood Hits	332	Shared Neighborhood Hits	61
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

TMEPA_HUMAN
NC score	0.012662 (rank : 1030)	θ value	8.99809 (rank : 867)
Query Neighborhood Hits	872	Target Neighborhood Hits	46	Shared Neighborhood Hits	20
SwissProt Accessions	Q969W9, Q5TDR6, Q96B72, Q9UJD3	Gene names	TMEPAI, PMEPA1, STAG1
Domain Architecture
Description	Transmembrane prostate androgen-induced protein (Solid tumor- associated 1 protein).

HXB4_MOUSE
NC score	0.012575 (rank : 1031)	θ value	3.0926 (rank : 649)
Query Neighborhood Hits	872	Target Neighborhood Hits	375	Shared Neighborhood Hits	49
SwissProt Accessions	P10284, Q3UZB4, Q4VBG0	Gene names	Hoxb4, Hox-2.6, Hoxb-4
Domain Architecture
Description	Homeobox protein Hox-B4 (Hox-2.6).

LRP5_HUMAN
NC score	0.012561 (rank : 1032)	θ value	0.163984 (rank : 345)
Query Neighborhood Hits	872	Target Neighborhood Hits	224	Shared Neighborhood Hits	15
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

KLF2_HUMAN
NC score	0.012549 (rank : 1033)	θ value	1.09739e-05 (rank : 75)
Query Neighborhood Hits	872	Target Neighborhood Hits	755	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Y5W3, Q9UJS5, Q9UKR6	Gene names	KLF2, LKLF
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 2 (Lung krueppel-like factor).

ST5_HUMAN
NC score	0.012299 (rank : 1034)	θ value	8.99809 (rank : 863)
Query Neighborhood Hits	872	Target Neighborhood Hits	151	Shared Neighborhood Hits	36
SwissProt Accessions	P78524, P78523, Q16492, Q7KYY2, Q7KZ12, Q8NE12, Q9BQQ6	Gene names	ST5, DENND2B, HTS1
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (HeLa tumor suppression 1) (DENN domain-containing protein 2B).

ZEP2_HUMAN
NC score	0.012245 (rank : 1035)	θ value	3.0926 (rank : 667)
Query Neighborhood Hits	872	Target Neighborhood Hits	937	Shared Neighborhood Hits	102
SwissProt Accessions	P31629, Q02646, Q5THT5, Q9NS05	Gene names	HIVEP2
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 (HIV- EP2) (MHC-binding protein 2) (MBP-2).

FBN1_MOUSE
NC score	0.012241 (rank : 1036)	θ value	0.813845 (rank : 457)
Query Neighborhood Hits	872	Target Neighborhood Hits	563	Shared Neighborhood Hits	32
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

GP156_MOUSE
NC score	0.012043 (rank : 1037)	θ value	5.27518 (rank : 725)
Query Neighborhood Hits	872	Target Neighborhood Hits	95	Shared Neighborhood Hits	24
SwissProt Accessions	Q6PCP7, Q8K452	Gene names	Gpr156, Gababl
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor).

DBX1_MOUSE
NC score	0.011860 (rank : 1038)	θ value	6.88961 (rank : 765)
Query Neighborhood Hits	872	Target Neighborhood Hits	346	Shared Neighborhood Hits	30
SwissProt Accessions	P52950	Gene names	Dbx1, Dbx
Domain Architecture
Description	Homeobox protein DBX1.

STF1_MOUSE
NC score	0.011834 (rank : 1039)	θ value	1.38821 (rank : 550)
Query Neighborhood Hits	872	Target Neighborhood Hits	137	Shared Neighborhood Hits	23
SwissProt Accessions	P33242	Gene names	Nr5a1, Ftzf1
Domain Architecture
Description	Steroidogenic factor 1 (STF-1) (SF-1) (Adrenal 4-binding protein) (Steroid hormone receptor Ad4BP) (Fushi tarazu factor homolog 1) (Embryonal LTR-binding protein) (ELP) (Embryonal long terminal repeat- binding protein) (Steroid hydroxylase positive regulator).

TS101_MOUSE
NC score	0.011764 (rank : 1040)	θ value	6.88961 (rank : 797)
Query Neighborhood Hits	872	Target Neighborhood Hits	312	Shared Neighborhood Hits	19
SwissProt Accessions	Q61187	Gene names	Tsg101
Domain Architecture
Description	Tumor susceptibility gene 101 protein.

FCRLA_HUMAN
NC score	0.011713 (rank : 1041)	θ value	3.0926 (rank : 642)
Query Neighborhood Hits	872	Target Neighborhood Hits	135	Shared Neighborhood Hits	23
SwissProt Accessions	Q7L513, Q5VXA1, Q5VXA2, Q5VXA3, Q5VXB0, Q8NEW4, Q8WXH3, Q96PC6, Q96PJ0, Q96PJ1, Q96PJ2, Q96PJ4, Q9BR57	Gene names	FCRLA, FCRL, FCRL1, FCRLM1, FCRX, FREB
Domain Architecture	No domain graphic available
Description	Fc receptor-like and mucin-like 1 precursor (Fc receptor-like A) (Fc receptor homolog expressed in B-cells) (Fc receptor-related protein X) (FcRX) (Fc receptor-like protein).

B3GT6_HUMAN
NC score	0.011386 (rank : 1042)	θ value	1.81305 (rank : 556)
Query Neighborhood Hits	872	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q96L58, Q5T7M5	Gene names	B3GALT6
Domain Architecture	No domain graphic available
Description	Beta-1,3-galactosyltransferase 6 (EC 2.4.1.134) (beta 3GalT6) (Galactosylxylosylprotein 3-beta-galactosyltransferase) (UDP- Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6) (Galactosyltransferase II) (GAG GalTII).

EFNB3_MOUSE
NC score	0.011337 (rank : 1043)	θ value	3.0926 (rank : 639)
Query Neighborhood Hits	872	Target Neighborhood Hits	50	Shared Neighborhood Hits	11
SwissProt Accessions	O35393	Gene names	Efnb3
Domain Architecture
Description	Ephrin-B3 precursor.

OST4_HUMAN
NC score	0.011328 (rank : 1044)	θ value	4.03905 (rank : 689)
Query Neighborhood Hits	872	Target Neighborhood Hits	95	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y661, Q5QI42, Q8NDC2	Gene names	HS3ST4, 3OST4
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 4 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4) (Heparan sulfate 3-O-sulfotransferase 4) (h3-OST-4).

MK15_HUMAN
NC score	0.011269 (rank : 1045)	θ value	2.36792 (rank : 607)
Query Neighborhood Hits	872	Target Neighborhood Hits	1038	Shared Neighborhood Hits	139
SwissProt Accessions	Q8TD08, Q2TCF9, Q8N362	Gene names	MAPK15, ERK8
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 8).

ARTN_HUMAN
NC score	0.011261 (rank : 1046)	θ value	6.88961 (rank : 754)
Query Neighborhood Hits	872	Target Neighborhood Hits	42	Shared Neighborhood Hits	10
SwissProt Accessions	Q5T4W7, O95441, O96030, Q6P6A3	Gene names	ARTN, EVN
Domain Architecture	No domain graphic available
Description	Artemin precursor (Enovin) (Neublastin).

FOSL1_HUMAN
NC score	0.011091 (rank : 1047)	θ value	3.0926 (rank : 644)
Query Neighborhood Hits	872	Target Neighborhood Hits	112	Shared Neighborhood Hits	14
SwissProt Accessions	P15407	Gene names	FOSL1, FRA1
Domain Architecture
Description	Fos-related antigen 1 (FRA-1).

FOXO1_MOUSE
NC score	0.010984 (rank : 1048)	θ value	5.27518 (rank : 718)
Query Neighborhood Hits	872	Target Neighborhood Hits	118	Shared Neighborhood Hits	24
SwissProt Accessions	Q9R1E0	Gene names	Foxo1a, Fkhr, Foxo1
Domain Architecture
Description	Forkhead box protein O1A (Forkhead in rhabdomyosarcoma).

TOIP2_HUMAN
NC score	0.010968 (rank : 1049)	θ value	5.27518 (rank : 743)
Query Neighborhood Hits	872	Target Neighborhood Hits	102	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NFQ8	Gene names	TOR1AIP2, LULL1
Domain Architecture	No domain graphic available
Description	Torsin-1A-interacting protein 2 (Lumenal domain-like LAP1).

NECD_HUMAN
NC score	0.010894 (rank : 1050)	θ value	0.813845 (rank : 466)
Query Neighborhood Hits	872	Target Neighborhood Hits	82	Shared Neighborhood Hits	19
SwissProt Accessions	Q99608	Gene names	NDN
Domain Architecture
Description	Necdin.

SPHK2_HUMAN
NC score	0.010743 (rank : 1051)	θ value	6.88961 (rank : 793)
Query Neighborhood Hits	872	Target Neighborhood Hits	81	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NRA0, Q9BRN1, Q9H0Q2, Q9NWU7	Gene names	SPHK2
Domain Architecture
Description	Sphingosine kinase 2 (EC 2.7.1.-) (SK 2) (SPK 2).

STF1_HUMAN
NC score	0.010569 (rank : 1052)	θ value	4.03905 (rank : 696)
Query Neighborhood Hits	872	Target Neighborhood Hits	132	Shared Neighborhood Hits	25
SwissProt Accessions	Q13285, O15196	Gene names	NR5A1, AD4BP, FTZF1, SF1
Domain Architecture
Description	Steroidogenic factor 1 (STF-1) (SF-1) (Adrenal 4-binding protein) (Steroid hormone receptor Ad4BP) (Fushi tarazu factor homolog 1).

DUS8_MOUSE
NC score	0.010537 (rank : 1053)	θ value	4.03905 (rank : 679)
Query Neighborhood Hits	872	Target Neighborhood Hits	119	Shared Neighborhood Hits	23
SwissProt Accessions	O09112	Gene names	Dusp8, Nttp1
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Neuronal tyrosine threonine phosphatase 1).

VAX1_HUMAN
NC score	0.010445 (rank : 1054)	θ value	5.27518 (rank : 746)
Query Neighborhood Hits	872	Target Neighborhood Hits	355	Shared Neighborhood Hits	30
SwissProt Accessions	Q5SQQ9, Q6ZSX0	Gene names	VAX1
Domain Architecture	No domain graphic available
Description	Ventral anterior homeobox 1.

CAR10_HUMAN
NC score	0.010126 (rank : 1055)	θ value	6.88961 (rank : 758)
Query Neighborhood Hits	872	Target Neighborhood Hits	569	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BWT7, Q14CQ8, Q5TFG6, Q9UGR5, Q9UGR6, Q9Y3H0	Gene names	CARD10, CARMA3
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (CARD-containing MAGUK protein 3) (Carma 3).

CAP1_MOUSE
NC score	0.010058 (rank : 1056)	θ value	5.27518 (rank : 707)
Query Neighborhood Hits	872	Target Neighborhood Hits	46	Shared Neighborhood Hits	17
SwissProt Accessions	P40124	Gene names	Cap1, Cap
Domain Architecture
Description	Adenylyl cyclase-associated protein 1 (CAP 1).

ETV3_MOUSE
NC score	0.009997 (rank : 1057)	θ value	8.99809 (rank : 823)
Query Neighborhood Hits	872	Target Neighborhood Hits	128	Shared Neighborhood Hits	33
SwissProt Accessions	Q8R4Z4, Q9QZW1	Gene names	Etv3, Mets, Pe1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

JUND_MOUSE
NC score	0.009740 (rank : 1058)	θ value	3.0926 (rank : 651)
Query Neighborhood Hits	872	Target Neighborhood Hits	134	Shared Neighborhood Hits	16
SwissProt Accessions	P15066	Gene names	Jund, Jun-d, Jund1
Domain Architecture
Description	Transcription factor jun-D.

ETV4_MOUSE
NC score	0.009707 (rank : 1059)	θ value	6.88961 (rank : 769)
Query Neighborhood Hits	872	Target Neighborhood Hits	100	Shared Neighborhood Hits	23
SwissProt Accessions	P28322	Gene names	Etv4, Pea-3, Pea3
Domain Architecture
Description	ETS translocation variant 4 (Polyomavirus enhancer activator 3) (Protein PEA3).

SMAD5_MOUSE
NC score	0.009330 (rank : 1060)	θ value	0.813845 (rank : 477)
Query Neighborhood Hits	872	Target Neighborhood Hits	74	Shared Neighborhood Hits	19
SwissProt Accessions	P97454, P70341, Q810K0	Gene names	Smad5, Madh5, Msmad5
Domain Architecture
Description	Mothers against decapentaplegic homolog 5 (SMAD 5) (Mothers against DPP homolog 5) (Smad5) (mSmad5) (Dwarfin-C) (Dwf-C).

PRGC1_HUMAN
NC score	0.009094 (rank : 1061)	θ value	8.99809 (rank : 853)
Query Neighborhood Hits	872	Target Neighborhood Hits	157	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UBK2, Q9UN32	Gene names	PPARGC1A, LEM6, PGC1, PGC1A, PPARGC1
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPAR gamma coactivator 1-alpha) (PPARGC-1-alpha) (PGC-1-alpha) (Ligand effect modulator 6).

TTBK1_HUMAN
NC score	0.009060 (rank : 1062)	θ value	6.88961 (rank : 798)
Query Neighborhood Hits	872	Target Neighborhood Hits	1058	Shared Neighborhood Hits	121
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

EFNB3_HUMAN
NC score	0.008988 (rank : 1063)	θ value	8.99809 (rank : 821)
Query Neighborhood Hits	872	Target Neighborhood Hits	48	Shared Neighborhood Hits	12
SwissProt Accessions	Q15768, O00680, Q8TBH7, Q92875	Gene names	EFNB3, EPLG8, LERK8
Domain Architecture
Description	Ephrin-B3 precursor (EPH-related receptor tyrosine kinase ligand 8) (LERK-8) (EPH-related receptor transmembrane ligand ELK-L3).

SP7_MOUSE
NC score	0.008851 (rank : 1064)	θ value	0.47712 (rank : 422)
Query Neighborhood Hits	872	Target Neighborhood Hits	756	Shared Neighborhood Hits	77
SwissProt Accessions	Q8VI67, Q8C5R3, Q8C6A7	Gene names	Sp7, Osx
Domain Architecture	No domain graphic available
Description	Transcription factor Sp7 (Zinc finger protein osterix) (C22).

GHR_HUMAN
NC score	0.008829 (rank : 1065)	θ value	5.27518 (rank : 724)
Query Neighborhood Hits	872	Target Neighborhood Hits	57	Shared Neighborhood Hits	8
SwissProt Accessions	P10912, Q9HCX2	Gene names	GHR
Domain Architecture
Description	Growth hormone receptor precursor (GH receptor) (Somatotropin receptor) [Contains: Growth hormone-binding protein (GH-binding protein) (GHBP) (Serum-binding protein)].

KI13B_HUMAN
NC score	0.008811 (rank : 1066)	θ value	0.813845 (rank : 462)
Query Neighborhood Hits	872	Target Neighborhood Hits	492	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NQT8, O75134, Q9BYJ6	Gene names	KIF13B, GAKIN, KIAA0639
Domain Architecture
Description	Kinesin-like protein KIF13B (Kinesin-like protein GAKIN).

PG12B_MOUSE
NC score	0.008783 (rank : 1067)	θ value	5.27518 (rank : 729)
Query Neighborhood Hits	872	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q99P27	Gene names	Pla2g12b, Pla2g13
Domain Architecture
Description	Group XIIB secretory phospholipase A2-like protein precursor (Group XIII secretory phospholipase A2-like protein) (GXIII sPLA2-like) (GXIIB).

JUND_HUMAN
NC score	0.008724 (rank : 1068)	θ value	8.99809 (rank : 834)
Query Neighborhood Hits	872	Target Neighborhood Hits	122	Shared Neighborhood Hits	14
SwissProt Accessions	P17535	Gene names	JUND
Domain Architecture
Description	Transcription factor jun-D.

DYNA_MOUSE
NC score	0.008567 (rank : 1069)	θ value	5.27518 (rank : 716)
Query Neighborhood Hits	872	Target Neighborhood Hits	1084	Shared Neighborhood Hits	75
SwissProt Accessions	O08788	Gene names	Dctn1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued).

KCNN2_MOUSE
NC score	0.008517 (rank : 1070)	θ value	0.62314 (rank : 437)
Query Neighborhood Hits	872	Target Neighborhood Hits	120	Shared Neighborhood Hits	4
SwissProt Accessions	P58390	Gene names	Kcnn2, Sk2
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 2 (SK2).

TBCD3_HUMAN
NC score	0.008209 (rank : 1071)	θ value	3.0926 (rank : 663)
Query Neighborhood Hits	872	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IZP1, Q9H0B9, Q9UDD4	Gene names	TBC1D3, PRC17
Domain Architecture
Description	TBC1 domain family member 3 (Rab GTPase-activating protein PRC17) (Prostate cancer gene 17 protein) (TRE17 alpha protein).

MCM3A_HUMAN
NC score	0.008201 (rank : 1072)	θ value	8.99809 (rank : 843)
Query Neighborhood Hits	872	Target Neighborhood Hits	86	Shared Neighborhood Hits	15
SwissProt Accessions	O60318, Q9UMT4	Gene names	MCM3AP, GANP, KIAA0572, MAP80
Domain Architecture
Description	80 kDa MCM3-associated protein (GANP protein).

CSKP_HUMAN
NC score	0.008194 (rank : 1073)	θ value	8.99809 (rank : 812)
Query Neighborhood Hits	872	Target Neighborhood Hits	1022	Shared Neighborhood Hits	106
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

ADA19_MOUSE
NC score	0.007896 (rank : 1074)	θ value	0.163984 (rank : 329)
Query Neighborhood Hits	872	Target Neighborhood Hits	315	Shared Neighborhood Hits	32
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

MICA2_HUMAN
NC score	0.007764 (rank : 1075)	θ value	5.27518 (rank : 727)
Query Neighborhood Hits	872	Target Neighborhood Hits	174	Shared Neighborhood Hits	22
SwissProt Accessions	O94851, Q7Z3A8	Gene names	MICAL2, KIAA0750
Domain Architecture
Description	Protein MICAL-2.

NKX28_HUMAN
NC score	0.007683 (rank : 1076)	θ value	8.99809 (rank : 849)
Query Neighborhood Hits	872	Target Neighborhood Hits	352	Shared Neighborhood Hits	29
SwissProt Accessions	O15522	Gene names	NKX2-8, NKX-2.8, NKX2G, NKX2H
Domain Architecture
Description	Homeobox protein Nkx-2.8 (Homeobox protein NK-2 homolog H).

CSKP_MOUSE
NC score	0.007572 (rank : 1077)	θ value	8.99809 (rank : 813)
Query Neighborhood Hits	872	Target Neighborhood Hits	1027	Shared Neighborhood Hits	111
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

ATOH1_HUMAN
NC score	0.007443 (rank : 1078)	θ value	5.27518 (rank : 706)
Query Neighborhood Hits	872	Target Neighborhood Hits	97	Shared Neighborhood Hits	5
SwissProt Accessions	Q92858	Gene names	ATOH1, ATH1
Domain Architecture
Description	Atonal protein homolog 1 (Helix-loop-helix protein hATH-1).

PLS1_HUMAN
NC score	0.006784 (rank : 1079)	θ value	5.27518 (rank : 730)
Query Neighborhood Hits	872	Target Neighborhood Hits	35	Shared Neighborhood Hits	8
SwissProt Accessions	O15162	Gene names	PLSCR1
Domain Architecture
Description	Phospholipid scramblase 1 (PL scramblase 1) (Ca(2+)-dependent phospholipid scramblase 1) (Erythrocyte phospholipid scramblase) (MmTRA1b).

ERBB2_HUMAN
NC score	0.006679 (rank : 1080)	θ value	0.47712 (rank : 407)
Query Neighborhood Hits	872	Target Neighborhood Hits	1073	Shared Neighborhood Hits	129
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

BC11A_MOUSE
NC score	0.006221 (rank : 1081)	θ value	0.47712 (rank : 402)
Query Neighborhood Hits	872	Target Neighborhood Hits	732	Shared Neighborhood Hits	38
SwissProt Accessions	Q9QYE3, Q80T89, Q8BLC7, Q8BLR4, Q8BWX3, Q921V4, Q9D0V2, Q9JIT4, Q9JLK8, Q9JLK9	Gene names	Bcl11a, Ctip1, Evi9, Kiaa1809
Domain Architecture	No domain graphic available
Description	B-cell lymphoma/leukemia 11A (B-cell CLL/lymphoma 11A) (COUP-TF- interacting protein 1) (Ecotropic viral integration site 9 protein) (EVI-9).

GLI1_HUMAN
NC score	0.006212 (rank : 1082)	θ value	0.0431538 (rank : 261)
Query Neighborhood Hits	872	Target Neighborhood Hits	828	Shared Neighborhood Hits	86
SwissProt Accessions	P08151, Q8TDN9	Gene names	GLI1, GLI
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI1 (Glioma-associated oncogene) (Oncogene GLI).

GLR_MOUSE
NC score	0.006174 (rank : 1083)	θ value	1.06291 (rank : 498)
Query Neighborhood Hits	872	Target Neighborhood Hits	79	Shared Neighborhood Hits	6
SwissProt Accessions	Q61606, Q63960	Gene names	Gcgr
Domain Architecture
Description	Glucagon receptor precursor (GL-R).

KLF2_MOUSE
NC score	0.006118 (rank : 1084)	θ value	0.0330416 (rank : 252)
Query Neighborhood Hits	872	Target Neighborhood Hits	738	Shared Neighborhood Hits	60
SwissProt Accessions	Q60843	Gene names	Klf2, Lklf
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 2 (Lung krueppel-like factor).

TITIN_HUMAN
NC score	0.006085 (rank : 1085)	θ value	1.81305 (rank : 584)
Query Neighborhood Hits	872	Target Neighborhood Hits	2923	Shared Neighborhood Hits	230
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

MK07_HUMAN
NC score	0.006030 (rank : 1086)	θ value	2.36792 (rank : 606)
Query Neighborhood Hits	872	Target Neighborhood Hits	1087	Shared Neighborhood Hits	125
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

UBP21_MOUSE
NC score	0.005991 (rank : 1087)	θ value	1.06291 (rank : 519)
Query Neighborhood Hits	872	Target Neighborhood Hits	101	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QZL6, Q9D0R1	Gene names	Usp21, Usp23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21).

MK07_MOUSE
NC score	0.005954 (rank : 1088)	θ value	0.62314 (rank : 440)
Query Neighborhood Hits	872	Target Neighborhood Hits	1054	Shared Neighborhood Hits	119
SwissProt Accessions	Q9WVS8	Gene names	Mapk7, Erk5
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase).

ZBTB4_HUMAN
NC score	0.005859 (rank : 1089)	θ value	0.365318 (rank : 399)
Query Neighborhood Hits	872	Target Neighborhood Hits	926	Shared Neighborhood Hits	77
SwissProt Accessions	Q9P1Z0, Q7Z697, Q86XJ4, Q8N4V8	Gene names	ZBTB4, KIAA1538
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 4 (KAISO-like zinc finger protein 1) (KAISO-L1).

SORC2_HUMAN
NC score	0.005727 (rank : 1090)	θ value	8.99809 (rank : 861)
Query Neighborhood Hits	872	Target Neighborhood Hits	66	Shared Neighborhood Hits	25
SwissProt Accessions	Q96PQ0, Q9P2L7	Gene names	SORCS2, KIAA1329
Domain Architecture
Description	VPS10 domain-containing receptor SorCS2 precursor.

KCNC3_HUMAN
NC score	0.005661 (rank : 1091)	θ value	8.99809 (rank : 836)
Query Neighborhood Hits	872	Target Neighborhood Hits	256	Shared Neighborhood Hits	68
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

EDEM1_MOUSE
NC score	0.005589 (rank : 1092)	θ value	4.03905 (rank : 680)
Query Neighborhood Hits	872	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q925U4	Gene names	Edem1, Edem
Domain Architecture
Description	ER degradation-enhancing alpha-mannosidase-like 1.

DAB2P_HUMAN
NC score	0.005511 (rank : 1093)	θ value	8.99809 (rank : 815)
Query Neighborhood Hits	872	Target Neighborhood Hits	303	Shared Neighborhood Hits	33
SwissProt Accessions	Q5VWQ8, Q8TDL2, Q96SE1, Q9C0C0	Gene names	DAB2IP, AF9Q34, AIP1, KIAA1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein) (DAB2 interaction protein) (ASK-interacting protein 1).

SP7_HUMAN
NC score	0.005489 (rank : 1094)	θ value	1.06291 (rank : 513)
Query Neighborhood Hits	872	Target Neighborhood Hits	734	Shared Neighborhood Hits	60
SwissProt Accessions	Q8TDD2	Gene names	SP7, OSX
Domain Architecture	No domain graphic available
Description	Transcription factor Sp7 (Zinc finger protein osterix).

TEAD3_HUMAN
NC score	0.005216 (rank : 1095)	θ value	4.03905 (rank : 701)
Query Neighborhood Hits	872	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q99594, O95910, Q8N6Y4	Gene names	TEAD3, TEF5
Domain Architecture
Description	Transcriptional enhancer factor TEF-5 (TEA domain family member 3) (TEAD-3) (DTEF-1).

BC11A_HUMAN
NC score	0.004864 (rank : 1096)	θ value	0.47712 (rank : 401)
Query Neighborhood Hits	872	Target Neighborhood Hits	745	Shared Neighborhood Hits	40
SwissProt Accessions	Q9H165, Q86W14, Q8WU92, Q96JL6, Q9H163, Q9H164, Q9H3G9, Q9NWA7	Gene names	BCL11A, CTIP1, EVI9, KIAA1809
Domain Architecture	No domain graphic available
Description	B-cell lymphoma/leukemia 11A (B-cell CLL/lymphoma 11A) (COUP-TF- interacting protein 1) (Ecotropic viral integration site 9 protein) (EVI-9).

MAST3_HUMAN
NC score	0.004768 (rank : 1097)	θ value	0.0563607 (rank : 279)
Query Neighborhood Hits	872	Target Neighborhood Hits	1128	Shared Neighborhood Hits	114
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

EOMES_HUMAN
NC score	0.004762 (rank : 1098)	θ value	1.06291 (rank : 496)
Query Neighborhood Hits	872	Target Neighborhood Hits	57	Shared Neighborhood Hits	6
SwissProt Accessions	O95936, Q8TAZ2, Q9UPM7	Gene names	EOMES, TBR2
Domain Architecture
Description	Eomesodermin homolog.

BC11B_MOUSE
NC score	0.004722 (rank : 1099)	θ value	0.813845 (rank : 449)
Query Neighborhood Hits	872	Target Neighborhood Hits	767	Shared Neighborhood Hits	50
SwissProt Accessions	Q99PV8, Q8C2I1, Q99PV6, Q99PV7, Q9JLF8	Gene names	Bcl11b, Ctip2, Rit1
Domain Architecture	No domain graphic available
Description	B-cell lymphoma/leukemia 11B (B-cell CLL/lymphoma 11B) (Radiation- induced tumor suppressor gene 1 protein) (mRit1) (COUP-TF-interacting protein 2).

ZDH14_MOUSE
NC score	0.004265 (rank : 1100)	θ value	6.88961 (rank : 800)
Query Neighborhood Hits	872	Target Neighborhood Hits	67	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BQQ1, Q8BNR2, Q8CFN0	Gene names	Zdhhc14
Domain Architecture	No domain graphic available
Description	Probable palmitoyltransferase ZDHHC14 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 14) (DHHC-14) (NEW1 domain-containing protein) (NEW1CP).

BC11B_HUMAN
NC score	0.003698 (rank : 1101)	θ value	3.0926 (rank : 631)
Query Neighborhood Hits	872	Target Neighborhood Hits	761	Shared Neighborhood Hits	48
SwissProt Accessions	Q9C0K0, Q9H162	Gene names	BCL11B, CTIP2, RIT1
Domain Architecture	No domain graphic available
Description	B-cell lymphoma/leukemia 11B (B-cell CLL/lymphoma 11B) (Radiation- induced tumor suppressor gene 1 protein) (hRit1) (COUP-TF-interacting protein 2).

SBK1_HUMAN
NC score	0.003672 (rank : 1102)	θ value	0.00102713 (rank : 128)
Query Neighborhood Hits	872	Target Neighborhood Hits	828	Shared Neighborhood Hits	40
SwissProt Accessions	Q52WX2	Gene names	SBK1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SBK1 (EC 2.7.11.1) (SH3-binding kinase 1).

PAK4_MOUSE
NC score	0.003560 (rank : 1103)	θ value	8.99809 (rank : 851)
Query Neighborhood Hits	872	Target Neighborhood Hits	1098	Shared Neighborhood Hits	132
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

KBTBB_HUMAN
NC score	0.003109 (rank : 1104)	θ value	8.99809 (rank : 835)
Query Neighborhood Hits	872	Target Neighborhood Hits	195	Shared Neighborhood Hits	21
SwissProt Accessions	O94819	Gene names	KBTBD11, KIAA0711, KLHDC7C
Domain Architecture	No domain graphic available
Description	Kelch repeat and BTB domain-containing protein 11 (Kelch domain- containing protein 7B).

OST2_MOUSE
NC score	0.002918 (rank : 1105)	θ value	8.99809 (rank : 850)
Query Neighborhood Hits	872	Target Neighborhood Hits	48	Shared Neighborhood Hits	9
SwissProt Accessions	Q673U1, Q8BLP1, Q8C055	Gene names	Hs3st2, 3ost2
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 2 (EC 2.8.2.29) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2) (Heparan sulfate 3-O-sulfotransferase 2).

GATA5_MOUSE
NC score	0.002847 (rank : 1106)	θ value	8.99809 (rank : 825)
Query Neighborhood Hits	872	Target Neighborhood Hits	51	Shared Neighborhood Hits	11
SwissProt Accessions	P97489	Gene names	Gata5
Domain Architecture
Description	Transcription factor GATA-5 (GATA-binding factor 5).

PCD15_HUMAN
NC score	0.002830 (rank : 1107)	θ value	1.81305 (rank : 578)
Query Neighborhood Hits	872	Target Neighborhood Hits	289	Shared Neighborhood Hits	48
SwissProt Accessions	Q96QU1, Q96QT8	Gene names	PCDH15
Domain Architecture
Description	Protocadherin-15 precursor.

GDF6_MOUSE
NC score	0.002805 (rank : 1108)	θ value	1.81305 (rank : 566)
Query Neighborhood Hits	872	Target Neighborhood Hits	68	Shared Neighborhood Hits	4
SwissProt Accessions	P43028, Q70UT4	Gene names	Gdf6, Gdf-6, Gdf16
Domain Architecture	No domain graphic available
Description	Growth/differentiation factor 6 precursor (GDF-6) (Growth/differentiation factor 16).

ACRO_HUMAN
NC score	0.002567 (rank : 1109)	θ value	0.279714 (rank : 370)
Query Neighborhood Hits	872	Target Neighborhood Hits	291	Shared Neighborhood Hits	46
SwissProt Accessions	P10323, Q6ICK2	Gene names	ACR, ACRS
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

GLI3_HUMAN
NC score	0.002482 (rank : 1110)	θ value	6.88961 (rank : 774)
Query Neighborhood Hits	872	Target Neighborhood Hits	871	Shared Neighborhood Hits	82
SwissProt Accessions	P10071, O75219, Q9UDT5, Q9UJ39	Gene names	GLI3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI3.

KLF1_MOUSE
NC score	0.002200 (rank : 1111)	θ value	1.38821 (rank : 537)
Query Neighborhood Hits	872	Target Neighborhood Hits	714	Shared Neighborhood Hits	44
SwissProt Accessions	P46099, O70261	Gene names	Klf1, Elkf
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 1 (Erythroid krueppel-like transcription factor) (EKLF) (Erythroid transcription factor).

ZBT45_HUMAN
NC score	0.002062 (rank : 1112)	θ value	0.365318 (rank : 398)
Query Neighborhood Hits	872	Target Neighborhood Hits	901	Shared Neighborhood Hits	94
SwissProt Accessions	Q96K62	Gene names	ZBTB45, ZNF499
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 45 (Zinc finger protein 499).

INSM1_HUMAN
NC score	0.001577 (rank : 1113)	θ value	1.06291 (rank : 499)
Query Neighborhood Hits	872	Target Neighborhood Hits	683	Shared Neighborhood Hits	41
SwissProt Accessions	Q01101	Gene names	INSM1, IA1
Domain Architecture	No domain graphic available
Description	Insulinoma-associated protein 1 (Zinc finger protein IA-1).

PCD15_MOUSE
NC score	0.001426 (rank : 1114)	θ value	8.99809 (rank : 852)
Query Neighborhood Hits	872	Target Neighborhood Hits	262	Shared Neighborhood Hits	41
SwissProt Accessions	Q99PJ1	Gene names	Pcdh15
Domain Architecture
Description	Protocadherin-15 precursor.

GLIS3_HUMAN
NC score	0.000807 (rank : 1115)	θ value	0.21417 (rank : 364)
Query Neighborhood Hits	872	Target Neighborhood Hits	758	Shared Neighborhood Hits	52
SwissProt Accessions	Q8NEA6	Gene names	GLIS3, ZNF515
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS3 (GLI-similar 3) (Zinc finger protein 515).

FZD8_HUMAN
NC score	0.000690 (rank : 1116)	θ value	5.27518 (rank : 721)
Query Neighborhood Hits	872	Target Neighborhood Hits	88	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H461	Gene names	FZD8
Domain Architecture
Description	Frizzled-8 precursor (Fz-8) (hFz8).

ATS20_MOUSE
NC score	0.000588 (rank : 1117)	θ value	4.03905 (rank : 672)
Query Neighborhood Hits	872	Target Neighborhood Hits	225	Shared Neighborhood Hits	12
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

GDF6_HUMAN
NC score	0.000476 (rank : 1118)	θ value	8.99809 (rank : 826)
Query Neighborhood Hits	872	Target Neighborhood Hits	76	Shared Neighborhood Hits	6
SwissProt Accessions	Q6KF10, Q6PI58	Gene names	GDF6, GDF16
Domain Architecture	No domain graphic available
Description	Growth/differentiation factor 6 precursor (GDF-6) (Growth/differentiation factor 16).

CELR3_HUMAN
NC score	0.000455 (rank : 1119)	θ value	8.99809 (rank : 808)
Query Neighborhood Hits	872	Target Neighborhood Hits	680	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

M3K14_MOUSE
NC score	0.000380 (rank : 1120)	θ value	8.99809 (rank : 842)
Query Neighborhood Hits	872	Target Neighborhood Hits	889	Shared Neighborhood Hits	66
SwissProt Accessions	Q9WUL6	Gene names	Map3k14, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF- kappa beta-inducing kinase) (Serine/threonine-protein kinase NIK).

KLF16_HUMAN
NC score	0.000065 (rank : 1121)	θ value	8.99809 (rank : 837)
Query Neighborhood Hits	872	Target Neighborhood Hits	737	Shared Neighborhood Hits	51
SwissProt Accessions	Q9BXK1	Gene names	KLF16, BTEB4, NSLP2
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 16 (Transcription factor BTEB4) (Basic transcription element-binding protein 4) (BTE-binding protein 4) (Novel Sp1-like zinc finger transcription factor 2) (Transcription factor NSLP2).

KLF14_HUMAN
NC score	-0.000009 (rank : 1122)	θ value	2.36792 (rank : 601)
Query Neighborhood Hits	872	Target Neighborhood Hits	725	Shared Neighborhood Hits	41
SwissProt Accessions	Q8TD94	Gene names	KLF14, BTEB5
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 14 (Transcription factor BTEB5) (Basic transcription element-binding protein 5) (BTE-binding protein 5).

MYLK2_HUMAN
NC score	-0.000234 (rank : 1123)	θ value	3.0926 (rank : 655)
Query Neighborhood Hits	872	Target Neighborhood Hits	920	Shared Neighborhood Hits	78
SwissProt Accessions	Q9H1R3, Q96I84	Gene names	MYLK2
Domain Architecture
Description	Myosin light chain kinase 2, skeletal/cardiac muscle (EC 2.7.11.18) (MLCK2).

ABCA4_MOUSE
NC score	-0.001170 (rank : 1124)	θ value	6.88961 (rank : 750)
Query Neighborhood Hits	872	Target Neighborhood Hits	126	Shared Neighborhood Hits	10
SwissProt Accessions	O35600	Gene names	Abca4, Abcr
Domain Architecture
Description	Retinal-specific ATP-binding cassette transporter (ATP-binding cassette sub-family A member 4) (RIM ABC transporter) (RIM protein) (RmP).

CELR3_MOUSE
NC score	-0.001208 (rank : 1125)	θ value	8.99809 (rank : 809)
Query Neighborhood Hits	872	Target Neighborhood Hits	687	Shared Neighborhood Hits	47
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

INSM1_MOUSE
NC score	-0.001856 (rank : 1126)	θ value	8.99809 (rank : 831)
Query Neighborhood Hits	872	Target Neighborhood Hits	678	Shared Neighborhood Hits	36
SwissProt Accessions	Q63ZV0, Q9Z113	Gene names	Insm1, Ia1
Domain Architecture	No domain graphic available
Description	Insulinoma-associated protein 1 (Zinc finger protein IA-1).

TAF5_HUMAN
NC score	-0.002414 (rank : 1127)	θ value	6.88961 (rank : 796)
Query Neighborhood Hits	872	Target Neighborhood Hits	352	Shared Neighborhood Hits	15
SwissProt Accessions	Q15542, Q86UZ7, Q9Y4K5	Gene names	TAF5, TAF2D
Domain Architecture
Description	Transcription initiation factor TFIID subunit 5 (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100).

ZN341_HUMAN
NC score	-0.002660 (rank : 1128)	θ value	0.47712 (rank : 425)
Query Neighborhood Hits	872	Target Neighborhood Hits	803	Shared Neighborhood Hits	78
SwissProt Accessions	Q9BYN7, Q5JXM8, Q96ST5	Gene names	ZNF341
Domain Architecture	No domain graphic available
Description	Zinc finger protein 341.

TESK1_MOUSE
NC score	-0.002667 (rank : 1129)	θ value	4.03905 (rank : 702)
Query Neighborhood Hits	872	Target Neighborhood Hits	862	Shared Neighborhood Hits	51
SwissProt Accessions	O70146, O70147	Gene names	Tesk1
Domain Architecture
Description	Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein kinase 1).

TAF5_MOUSE
NC score	-0.002752 (rank : 1130)	θ value	8.99809 (rank : 865)
Query Neighborhood Hits	872	Target Neighborhood Hits	366	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C092, Q8BTR2	Gene names	Taf5
Domain Architecture
Description	Transcription initiation factor TFIID subunit 5 (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100).

K0999_MOUSE
NC score	-0.002872 (rank : 1131)	θ value	6.88961 (rank : 779)
Query Neighborhood Hits	872	Target Neighborhood Hits	931	Shared Neighborhood Hits	64
SwissProt Accessions	Q6P4S6, Q641L5, Q66JZ5, Q6ZQ09, Q8K075, Q9CYD5	Gene names	Kiaa0999
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase KIAA0999 (EC 2.7.11.1).

DYR1B_MOUSE
NC score	-0.002941 (rank : 1132)	θ value	3.0926 (rank : 638)
Query Neighborhood Hits	872	Target Neighborhood Hits	799	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Z188	Gene names	Dyrk1b
Domain Architecture
Description	Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1).

ALK_MOUSE
NC score	-0.002976 (rank : 1133)	θ value	6.88961 (rank : 753)
Query Neighborhood Hits	872	Target Neighborhood Hits	811	Shared Neighborhood Hits	40
SwissProt Accessions	P97793	Gene names	Alk
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

RTN4R_MOUSE
NC score	-0.003062 (rank : 1134)	θ value	8.99809 (rank : 859)
Query Neighborhood Hits	872	Target Neighborhood Hits	293	Shared Neighborhood Hits	32
SwissProt Accessions	Q99PI8, Q80WQ1	Gene names	Rtn4r, Nogor
Domain Architecture	No domain graphic available
Description	Reticulon-4 receptor precursor (Nogo receptor) (NgR) (Nogo-66 receptor).

NUAK1_MOUSE
NC score	-0.003187 (rank : 1135)	θ value	4.03905 (rank : 687)
Query Neighborhood Hits	872	Target Neighborhood Hits	881	Shared Neighborhood Hits	46
SwissProt Accessions	Q641K5, Q6I6D6, Q8CGE1	Gene names	Nuak1, Kiaa0537
Domain Architecture	No domain graphic available
Description	NUAK family SNF1-like kinase 1 (EC 2.7.11.1).

DCAK1_HUMAN
NC score	-0.004519 (rank : 1136)	θ value	5.27518 (rank : 711)
Query Neighborhood Hits	872	Target Neighborhood Hits	877	Shared Neighborhood Hits	40
SwissProt Accessions	O15075	Gene names	DCAMKL1, KIAA0369
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 1).

FIZ1_HUMAN
NC score	-0.004677 (rank : 1137)	θ value	0.47712 (rank : 408)
Query Neighborhood Hits	872	Target Neighborhood Hits	715	Shared Neighborhood Hits	38
SwissProt Accessions	Q96SL8, Q6ZMJ7	Gene names	FIZ1
Domain Architecture	No domain graphic available
Description	Flt3-interacting zinc finger protein 1.

ZN263_HUMAN
NC score	-0.004742 (rank : 1138)	θ value	0.279714 (rank : 387)
Query Neighborhood Hits	872	Target Neighborhood Hits	795	Shared Neighborhood Hits	52
SwissProt Accessions	O14978, O43387, Q96H95	Gene names	ZNF263, FPM315
Domain Architecture
Description	Zinc finger protein 263 (Zinc finger protein FPM315).

DRD4_HUMAN
NC score	-0.005702 (rank : 1139)	θ value	0.0736092 (rank : 292)
Query Neighborhood Hits	872	Target Neighborhood Hits	886	Shared Neighborhood Hits	27
SwissProt Accessions	P21917	Gene names	DRD4
Domain Architecture
Description	D(4) dopamine receptor (Dopamine D4 receptor) (D(2C) dopamine receptor).

TRIM7_MOUSE
NC score	-0.005821 (rank : 1140)	θ value	8.99809 (rank : 868)
Query Neighborhood Hits	872	Target Neighborhood Hits	358	Shared Neighborhood Hits	11
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

ZN408_HUMAN
NC score	-0.006055 (rank : 1141)	θ value	0.62314 (rank : 448)
Query Neighborhood Hits	872	Target Neighborhood Hits	775	Shared Neighborhood Hits	38
SwissProt Accessions	Q9H9D4	Gene names	ZNF408, PFM14, PRDM17
Domain Architecture	No domain graphic available
Description	Zinc finger protein 408 (PR-domain zinc finger protein 17).

AA2AR_MOUSE
NC score	-0.014778 (rank : 1142)	θ value	3.0926 (rank : 627)
Query Neighborhood Hits	872	Target Neighborhood Hits	883	Shared Neighborhood Hits	3
SwissProt Accessions	Q60613	Gene names	Adora2a
Domain Architecture
Description	Adenosine A2a receptor.