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Network neighborhood for query Sequence : JUND_HUMAN

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JUND_HUMAN
SwissProt Accessions	P17535	Gene names	JUND
Domain Architecture
Description	Transcription factor jun-D.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

JUND_HUMAN
θ value	3.66817e-102 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	122	Target Neighborhood Hits	122	Shared Neighborhood Hits	122
SwissProt Accessions	P17535	Gene names	JUND
Domain Architecture
Description	Transcription factor jun-D.

JUND_MOUSE
θ value	7.15887e-98 (rank : 2)	NC score	0.988016 (rank : 2)
Query Neighborhood Hits	122	Target Neighborhood Hits	134	Shared Neighborhood Hits	103
SwissProt Accessions	P15066	Gene names	Jund, Jun-d, Jund1
Domain Architecture
Description	Transcription factor jun-D.

JUN_HUMAN
θ value	1.2325e-65 (rank : 3)	NC score	0.961562 (rank : 4)
Query Neighborhood Hits	122	Target Neighborhood Hits	144	Shared Neighborhood Hits	87
SwissProt Accessions	P05412, Q96G93	Gene names	JUN
Domain Architecture
Description	Transcription factor AP-1 (Activator protein 1) (AP1) (Proto-oncogene c-jun) (V-jun avian sarcoma virus 17 oncogene homolog) (p39).

JUN_MOUSE
θ value	1.6097e-65 (rank : 4)	NC score	0.962914 (rank : 3)
Query Neighborhood Hits	122	Target Neighborhood Hits	145	Shared Neighborhood Hits	87
SwissProt Accessions	P05627	Gene names	Jun
Domain Architecture
Description	Transcription factor AP-1 (Activator protein 1) (AP1) (Proto-oncogene c-jun) (V-jun avian sarcoma virus 17 oncogene homolog) (Jun A) (AH119).

JUNB_MOUSE
θ value	3.2585e-50 (rank : 5)	NC score	0.920066 (rank : 6)
Query Neighborhood Hits	122	Target Neighborhood Hits	116	Shared Neighborhood Hits	64
SwissProt Accessions	P09450, Q8C2G9	Gene names	Junb, Jun-b
Domain Architecture
Description	Transcription factor jun-B.

JUNB_HUMAN
θ value	3.4976e-36 (rank : 6)	NC score	0.920455 (rank : 5)
Query Neighborhood Hits	122	Target Neighborhood Hits	97	Shared Neighborhood Hits	65
SwissProt Accessions	P17275, Q96GH3	Gene names	JUNB
Domain Architecture
Description	Transcription factor jun-B.

ATF7_HUMAN
θ value	1.25267e-09 (rank : 7)	NC score	0.509931 (rank : 9)
Query Neighborhood Hits	122	Target Neighborhood Hits	333	Shared Neighborhood Hits	52
SwissProt Accessions	P17544, Q13814	Gene names	ATF7, ATFA
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

ATF7_MOUSE
θ value	1.25267e-09 (rank : 8)	NC score	0.514808 (rank : 8)
Query Neighborhood Hits	122	Target Neighborhood Hits	286	Shared Neighborhood Hits	51
SwissProt Accessions	Q8R0S1	Gene names	Atf7
Domain Architecture	No domain graphic available
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

ATF2_HUMAN
θ value	8.97725e-08 (rank : 9)	NC score	0.481242 (rank : 11)
Query Neighborhood Hits	122	Target Neighborhood Hits	402	Shared Neighborhood Hits	50
SwissProt Accessions	P15336, Q13000	Gene names	ATF2, CREB2, CREBP1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (HB16).

ATF2_MOUSE
θ value	1.17247e-07 (rank : 10)	NC score	0.480526 (rank : 12)
Query Neighborhood Hits	122	Target Neighborhood Hits	397	Shared Neighborhood Hits	50
SwissProt Accessions	P16951, Q64089, Q64090, Q64091	Gene names	Atf2
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (MXBP protein).

CREB5_HUMAN
θ value	7.59969e-07 (rank : 11)	NC score	0.534717 (rank : 7)
Query Neighborhood Hits	122	Target Neighborhood Hits	222	Shared Neighborhood Hits	45
SwissProt Accessions	Q02930, Q05886, Q06246	Gene names	CREB5, CREBPA
Domain Architecture
Description	cAMP response element-binding protein 5 (CRE-BPa).

BACH1_HUMAN
θ value	3.19293e-05 (rank : 12)	NC score	0.255109 (rank : 41)
Query Neighborhood Hits	122	Target Neighborhood Hits	289	Shared Neighborhood Hits	61
SwissProt Accessions	O14867, O43285	Gene names	BACH1
Domain Architecture
Description	Transcription regulator protein BACH1 (BTB and CNC homolog 1) (HA2303).

BACH1_MOUSE
θ value	5.44631e-05 (rank : 13)	NC score	0.250600 (rank : 42)
Query Neighborhood Hits	122	Target Neighborhood Hits	289	Shared Neighborhood Hits	60
SwissProt Accessions	P97302	Gene names	Bach1
Domain Architecture
Description	Transcription regulator protein BACH1 (BTB and CNC homolog 1).

NFE2_HUMAN
θ value	7.1131e-05 (rank : 14)	NC score	0.397441 (rank : 18)
Query Neighborhood Hits	122	Target Neighborhood Hits	66	Shared Neighborhood Hits	29
SwissProt Accessions	Q16621, Q07720, Q6ICV9	Gene names	NFE2
Domain Architecture	No domain graphic available
Description	Transcription factor NF-E2 45 kDa subunit (Nuclear factor, erythroid- derived 2 45 kDa subunit) (p45 NF-E2) (Leucine zipper protein NF-E2).

XBP1_HUMAN
θ value	0.000158464 (rank : 15)	NC score	0.360668 (rank : 28)
Query Neighborhood Hits	122	Target Neighborhood Hits	109	Shared Neighborhood Hits	39
SwissProt Accessions	P17861, Q8WYK6, Q969P1, Q96BD7	Gene names	XBP1, TREB5, XBP2
Domain Architecture	No domain graphic available
Description	X box-binding protein 1 (XBP-1) (Tax-responsive element-binding protein 5).

FOSB_HUMAN
θ value	0.00020696 (rank : 16)	NC score	0.427848 (rank : 17)
Query Neighborhood Hits	122	Target Neighborhood Hits	141	Shared Neighborhood Hits	47
SwissProt Accessions	P53539	Gene names	FOSB, G0S3
Domain Architecture	No domain graphic available
Description	Protein fosB (G0/G1 switch regulatory protein 3).

FOSB_MOUSE
θ value	0.00020696 (rank : 17)	NC score	0.428834 (rank : 16)
Query Neighborhood Hits	122	Target Neighborhood Hits	137	Shared Neighborhood Hits	47
SwissProt Accessions	P13346	Gene names	Fosb
Domain Architecture	No domain graphic available
Description	Protein fosB.

XBP1_MOUSE
θ value	0.00020696 (rank : 18)	NC score	0.369558 (rank : 26)
Query Neighborhood Hits	122	Target Neighborhood Hits	99	Shared Neighborhood Hits	46
SwissProt Accessions	O35426, Q8VHM0, Q922G5, Q9ESS3	Gene names	Xbp1, Treb5
Domain Architecture	No domain graphic available
Description	X box-binding protein 1 (XBP-1) (Tax-responsive element-binding protein 5 homolog).

BATF_MOUSE
θ value	0.000270298 (rank : 19)	NC score	0.440941 (rank : 15)
Query Neighborhood Hits	122	Target Neighborhood Hits	100	Shared Neighborhood Hits	52
SwissProt Accessions	O35284	Gene names	Batf
Domain Architecture
Description	ATF-like basic leucine zipper transcription factor B-ATF.

ATF3_HUMAN
θ value	0.00035302 (rank : 20)	NC score	0.489201 (rank : 10)
Query Neighborhood Hits	122	Target Neighborhood Hits	120	Shared Neighborhood Hits	62
SwissProt Accessions	P18847	Gene names	ATF3
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-3 (Activating transcription factor 3).

BATF_HUMAN
θ value	0.00035302 (rank : 21)	NC score	0.446665 (rank : 14)
Query Neighborhood Hits	122	Target Neighborhood Hits	80	Shared Neighborhood Hits	47
SwissProt Accessions	Q16520	Gene names	BATF
Domain Architecture
Description	ATF-like basic leucine zipper transcriptional factor B-ATF (SF-HT- activated gene 2) (SFA-2).

NIPBL_HUMAN
θ value	0.00035302 (rank : 22)	NC score	0.069811 (rank : 78)
Query Neighborhood Hits	122	Target Neighborhood Hits	1311	Shared Neighborhood Hits	22
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

BACH2_HUMAN
θ value	0.000602161 (rank : 23)	NC score	0.219211 (rank : 44)
Query Neighborhood Hits	122	Target Neighborhood Hits	234	Shared Neighborhood Hits	45
SwissProt Accessions	Q9BYV9, Q59H70, Q5T793, Q9NTS5	Gene names	BACH2
Domain Architecture
Description	Transcription regulator protein BACH2 (BTB and CNC homolog 2).

NF2L1_HUMAN
θ value	0.000602161 (rank : 24)	NC score	0.373445 (rank : 23)
Query Neighborhood Hits	122	Target Neighborhood Hits	169	Shared Neighborhood Hits	60
SwissProt Accessions	Q14494, Q12877, Q96FN6	Gene names	NFE2L1, HBZ17, NRF1, TCF11
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 1 (NF-E2-related factor 1) (NFE2-related factor 1) (Nuclear factor, erythroid derived 2, like 1) (Transcription factor 11) (Transcription factor HBZ17) (Transcription factor LCR-F1) (Locus control region-factor 1).

NF2L1_MOUSE
θ value	0.000602161 (rank : 25)	NC score	0.369866 (rank : 25)
Query Neighborhood Hits	122	Target Neighborhood Hits	185	Shared Neighborhood Hits	61
SwissProt Accessions	Q61985, O70234	Gene names	Nfe2l1, Nrf1
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 1 (NF-E2-related factor 1) (NFE2-related factor 1) (Nuclear factor, erythroid derived 2, like 1).

NF2L3_MOUSE
θ value	0.000602161 (rank : 26)	NC score	0.364766 (rank : 27)
Query Neighborhood Hits	122	Target Neighborhood Hits	93	Shared Neighborhood Hits	46
SwissProt Accessions	Q9WTM4	Gene names	Nfe2l3, Nrf3
Domain Architecture	No domain graphic available
Description	Nuclear factor erythroid 2-related factor 3 (NF-E2-related factor 3) (NFE2-related factor 3) (Nuclear factor, erythroid derived 2, like 3).

BACH2_MOUSE
θ value	0.00102713 (rank : 27)	NC score	0.217147 (rank : 45)
Query Neighborhood Hits	122	Target Neighborhood Hits	248	Shared Neighborhood Hits	46
SwissProt Accessions	P97303	Gene names	Bach2
Domain Architecture
Description	Transcription regulator protein BACH2 (BTB and CNC homolog 2).

NF2L2_HUMAN
θ value	0.00102713 (rank : 28)	NC score	0.332501 (rank : 32)
Query Neighborhood Hits	122	Target Neighborhood Hits	109	Shared Neighborhood Hits	35
SwissProt Accessions	Q16236, Q96F71	Gene names	NFE2L2, NRF2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2) (HEBP1).

ATF3_MOUSE
θ value	0.00175202 (rank : 29)	NC score	0.471120 (rank : 13)
Query Neighborhood Hits	122	Target Neighborhood Hits	120	Shared Neighborhood Hits	61
SwissProt Accessions	Q60765	Gene names	Atf3
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-3 (Activating transcription factor 3) (Transcription factor LRG-21).

ATF1_HUMAN
θ value	0.00298849 (rank : 30)	NC score	0.327091 (rank : 35)
Query Neighborhood Hits	122	Target Neighborhood Hits	59	Shared Neighborhood Hits	33
SwissProt Accessions	P18846, P25168	Gene names	ATF1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-1 (Activating transcription factor 1) (TREB36 protein).

CREB3_HUMAN
θ value	0.00298849 (rank : 31)	NC score	0.353432 (rank : 30)
Query Neighborhood Hits	122	Target Neighborhood Hits	138	Shared Neighborhood Hits	44
SwissProt Accessions	O43889, O14671, O14919, Q96GK8, Q9H2W3, Q9UE77	Gene names	CREB3, LZIP
Domain Architecture	No domain graphic available
Description	Cyclic AMP-responsive element-binding protein 3 (Luman protein) (Transcription factor LZIP-alpha).

CREM_HUMAN
θ value	0.00298849 (rank : 32)	NC score	0.317931 (rank : 37)
Query Neighborhood Hits	122	Target Neighborhood Hits	63	Shared Neighborhood Hits	31
SwissProt Accessions	Q03060, Q16114, Q16116, Q9NZB9	Gene names	CREM
Domain Architecture
Description	cAMP-responsive element modulator.

CREM_MOUSE
θ value	0.00298849 (rank : 33)	NC score	0.319823 (rank : 36)
Query Neighborhood Hits	122	Target Neighborhood Hits	58	Shared Neighborhood Hits	30
SwissProt Accessions	P27699, P27698	Gene names	Crem
Domain Architecture
Description	cAMP-responsive element modulator.

FOSL2_HUMAN
θ value	0.00298849 (rank : 34)	NC score	0.379112 (rank : 20)
Query Neighborhood Hits	122	Target Neighborhood Hits	158	Shared Neighborhood Hits	46
SwissProt Accessions	P15408	Gene names	FOSL2, FRA2
Domain Architecture	No domain graphic available
Description	Fos-related antigen 2.

NF2L3_HUMAN
θ value	0.00298849 (rank : 35)	NC score	0.348617 (rank : 31)
Query Neighborhood Hits	122	Target Neighborhood Hits	150	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y4A8, Q6NUS0, Q7Z498, Q86UJ4, Q86VR5, Q9UQA4	Gene names	NFE2L3, NRF3
Domain Architecture	No domain graphic available
Description	Nuclear factor erythroid 2-related factor 3 (NF-E2-related factor 3) (NFE2-related factor 3) (Nuclear factor, erythroid derived 2, like 3).

CREB1_HUMAN
θ value	0.00665767 (rank : 36)	NC score	0.298069 (rank : 40)
Query Neighborhood Hits	122	Target Neighborhood Hits	57	Shared Neighborhood Hits	30
SwissProt Accessions	P16220, P21934, Q9UMA7	Gene names	CREB1
Domain Architecture
Description	cAMP response element-binding protein (CREB).

CREB1_MOUSE
θ value	0.00665767 (rank : 37)	NC score	0.298105 (rank : 39)
Query Neighborhood Hits	122	Target Neighborhood Hits	58	Shared Neighborhood Hits	30
SwissProt Accessions	Q01147	Gene names	Creb1, Creb-1
Domain Architecture
Description	cAMP response element-binding protein (CREB).

FOSL2_MOUSE
θ value	0.00665767 (rank : 38)	NC score	0.370044 (rank : 24)
Query Neighborhood Hits	122	Target Neighborhood Hits	151	Shared Neighborhood Hits	47
SwissProt Accessions	P47930	Gene names	Fosl2, Fra-2, Fra2
Domain Architecture	No domain graphic available
Description	Fos-related antigen 2.

NF2L2_MOUSE
θ value	0.00665767 (rank : 39)	NC score	0.353757 (rank : 29)
Query Neighborhood Hits	122	Target Neighborhood Hits	183	Shared Neighborhood Hits	60
SwissProt Accessions	Q60795	Gene names	Nfe2l2, Nrf-2, Nrf2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2).

ATF1_MOUSE
θ value	0.00869519 (rank : 40)	NC score	0.316667 (rank : 38)
Query Neighborhood Hits	122	Target Neighborhood Hits	70	Shared Neighborhood Hits	31
SwissProt Accessions	P81269	Gene names	Atf1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-1 (Activating transcription factor 1) (TCR-ATF1).

CREB3_MOUSE
θ value	0.00869519 (rank : 41)	NC score	0.374580 (rank : 22)
Query Neighborhood Hits	122	Target Neighborhood Hits	97	Shared Neighborhood Hits	51
SwissProt Accessions	Q61817, Q99M21, Q9CVK9	Gene names	Creb3, Lzip
Domain Architecture	No domain graphic available
Description	Cyclic AMP-responsive element-binding protein 3 (Transcription factor LZIP).

RFIP4_HUMAN
θ value	0.0330416 (rank : 42)	NC score	0.084004 (rank : 72)
Query Neighborhood Hits	122	Target Neighborhood Hits	785	Shared Neighborhood Hits	43
SwissProt Accessions	Q86YS3, Q8N829, Q8NDT7, Q969D8	Gene names	RAB11FIP4, KIAA1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

CEBPG_MOUSE
θ value	0.0736092 (rank : 43)	NC score	0.153349 (rank : 58)
Query Neighborhood Hits	122	Target Neighborhood Hits	77	Shared Neighborhood Hits	24
SwissProt Accessions	P53568	Gene names	Cebpg
Domain Architecture
Description	CCAAT/enhancer-binding protein gamma (C/EBP gamma) (Immunoglobulin enhancer-binding protein 1) (IG/EBP-1) (Granulocyte colony-stimulating factor promoter element 1-binding protein) (GPE1-binding protein) (GPE1-BP).

FOSL1_HUMAN
θ value	0.0736092 (rank : 44)	NC score	0.376844 (rank : 21)
Query Neighborhood Hits	122	Target Neighborhood Hits	112	Shared Neighborhood Hits	45
SwissProt Accessions	P15407	Gene names	FOSL1, FRA1
Domain Architecture
Description	Fos-related antigen 1 (FRA-1).

FOSL1_MOUSE
θ value	0.0736092 (rank : 45)	NC score	0.383676 (rank : 19)
Query Neighborhood Hits	122	Target Neighborhood Hits	113	Shared Neighborhood Hits	43
SwissProt Accessions	P48755, O35285	Gene names	Fosl1, Fra1
Domain Architecture
Description	Fos-related antigen 1 (FRA-1).

FOS_HUMAN
θ value	0.0961366 (rank : 46)	NC score	0.329630 (rank : 34)
Query Neighborhood Hits	122	Target Neighborhood Hits	72	Shared Neighborhood Hits	39
SwissProt Accessions	P01100, P18849	Gene names	FOS, G0S7
Domain Architecture
Description	Proto-oncogene protein c-fos (Cellular oncogene fos) (G0/G1 switch regulatory protein 7).

FOS_MOUSE
θ value	0.0961366 (rank : 47)	NC score	0.331731 (rank : 33)
Query Neighborhood Hits	122	Target Neighborhood Hits	69	Shared Neighborhood Hits	39
SwissProt Accessions	P01101	Gene names	Fos
Domain Architecture
Description	Proto-oncogene protein c-fos (Cellular oncogene fos).

CEBPE_HUMAN
θ value	0.125558 (rank : 48)	NC score	0.197820 (rank : 46)
Query Neighborhood Hits	122	Target Neighborhood Hits	236	Shared Neighborhood Hits	35
SwissProt Accessions	Q15744, Q15745, Q8IYI2, Q99803	Gene names	CEBPE
Domain Architecture
Description	CCAAT/enhancer-binding protein epsilon (C/EBP epsilon).

CEBPG_HUMAN
θ value	0.163984 (rank : 49)	NC score	0.147234 (rank : 59)
Query Neighborhood Hits	122	Target Neighborhood Hits	101	Shared Neighborhood Hits	26
SwissProt Accessions	P53567, Q5U052	Gene names	CEBPG
Domain Architecture
Description	CCAAT/enhancer-binding protein gamma (C/EBP gamma).

MUC1_HUMAN
θ value	0.21417 (rank : 50)	NC score	0.011984 (rank : 127)
Query Neighborhood Hits	122	Target Neighborhood Hits	975	Shared Neighborhood Hits	12
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

MAFB_HUMAN
θ value	0.279714 (rank : 51)	NC score	0.183290 (rank : 50)
Query Neighborhood Hits	122	Target Neighborhood Hits	96	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y5Q3, Q9H1F1	Gene names	MAFB, KRML
Domain Architecture
Description	Transcription factor MafB (V-maf musculoaponeurotic fibrosarcoma oncogene homolog B).

MAFB_MOUSE
θ value	0.279714 (rank : 52)	NC score	0.183946 (rank : 48)
Query Neighborhood Hits	122	Target Neighborhood Hits	92	Shared Neighborhood Hits	43
SwissProt Accessions	P54841	Gene names	Mafb, Krml, Maf1
Domain Architecture
Description	Transcription factor MafB (V-maf musculoaponeurotic fibrosarcoma oncogene homolog B) (Transcription factor MAF1) (Segmentation protein KR) (Kreisler).

RIMB1_HUMAN
θ value	0.365318 (rank : 53)	NC score	0.061857 (rank : 82)
Query Neighborhood Hits	122	Target Neighborhood Hits	1479	Shared Neighborhood Hits	47
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

TNNT3_HUMAN
θ value	0.365318 (rank : 54)	NC score	0.072504 (rank : 77)
Query Neighborhood Hits	122	Target Neighborhood Hits	327	Shared Neighborhood Hits	21
SwissProt Accessions	P45378, Q12975, Q12976, Q12977, Q12978, Q86TH6	Gene names	TNNT3
Domain Architecture	No domain graphic available
Description	Troponin T, fast skeletal muscle (TnTf) (Fast skeletal muscle troponin T) (fTnT) (Beta TnTF).

TRIM8_MOUSE
θ value	0.365318 (rank : 55)	NC score	0.044735 (rank : 90)
Query Neighborhood Hits	122	Target Neighborhood Hits	674	Shared Neighborhood Hits	30
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

ATF6A_HUMAN
θ value	0.47712 (rank : 56)	NC score	0.233394 (rank : 43)
Query Neighborhood Hits	122	Target Neighborhood Hits	174	Shared Neighborhood Hits	62
SwissProt Accessions	P18850, O15139, Q5VW62, Q6IPB5, Q9UEC9	Gene names	ATF6
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 alpha (Activating transcription factor 6 alpha) (ATF6-alpha).

CTRO_MOUSE
θ value	0.47712 (rank : 57)	NC score	0.018784 (rank : 122)
Query Neighborhood Hits	122	Target Neighborhood Hits	2344	Shared Neighborhood Hits	45
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

RFIP4_MOUSE
θ value	0.47712 (rank : 58)	NC score	0.067003 (rank : 81)
Query Neighborhood Hits	122	Target Neighborhood Hits	708	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BQP8, Q80T87	Gene names	Rab11fip4, Kiaa1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

TBCD2_HUMAN
θ value	0.47712 (rank : 59)	NC score	0.047549 (rank : 87)
Query Neighborhood Hits	122	Target Neighborhood Hits	419	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

ATF5_HUMAN
θ value	0.62314 (rank : 60)	NC score	0.169666 (rank : 57)
Query Neighborhood Hits	122	Target Neighborhood Hits	99	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y2D1, Q9BSA1, Q9UNQ3	Gene names	ATF5, ATFX
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-5 (Activating transcription factor 5) (Transcription factor ATFx).

MAFK_HUMAN
θ value	0.62314 (rank : 61)	NC score	0.177880 (rank : 51)
Query Neighborhood Hits	122	Target Neighborhood Hits	73	Shared Neighborhood Hits	37
SwissProt Accessions	O60675	Gene names	MAFK
Domain Architecture
Description	Transcription factor MafK (Erythroid transcription factor NF-E2 p18 subunit).

MAFK_MOUSE
θ value	0.62314 (rank : 62)	NC score	0.177271 (rank : 53)
Query Neighborhood Hits	122	Target Neighborhood Hits	73	Shared Neighborhood Hits	37
SwissProt Accessions	Q61827, Q60600	Gene names	Mafk, Nfe2u
Domain Architecture
Description	Transcription factor MafK (Erythroid transcription factor NF-E2 p18 subunit).

NRL_HUMAN
θ value	0.62314 (rank : 63)	NC score	0.174270 (rank : 54)
Query Neighborhood Hits	122	Target Neighborhood Hits	39	Shared Neighborhood Hits	29
SwissProt Accessions	P54845	Gene names	NRL
Domain Architecture
Description	Neural retina-specific leucine zipper protein (NRL) (D14S46E).

NRL_MOUSE
θ value	0.62314 (rank : 64)	NC score	0.177546 (rank : 52)
Query Neighborhood Hits	122	Target Neighborhood Hits	36	Shared Neighborhood Hits	30
SwissProt Accessions	P54846	Gene names	Nrl
Domain Architecture
Description	Neural retina-specific leucine zipper protein (NRL).

CCD41_MOUSE
θ value	0.813845 (rank : 65)	NC score	0.044372 (rank : 91)
Query Neighborhood Hits	122	Target Neighborhood Hits	1399	Shared Neighborhood Hits	51
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

MAFG_HUMAN
θ value	0.813845 (rank : 66)	NC score	0.183971 (rank : 47)
Query Neighborhood Hits	122	Target Neighborhood Hits	85	Shared Neighborhood Hits	42
SwissProt Accessions	O15525	Gene names	MAFG
Domain Architecture
Description	Transcription factor MafG (V-maf musculoaponeurotic fibrosarcoma oncogene homolog G) (hMAF).

MAFG_MOUSE
θ value	0.813845 (rank : 67)	NC score	0.183542 (rank : 49)
Query Neighborhood Hits	122	Target Neighborhood Hits	90	Shared Neighborhood Hits	42
SwissProt Accessions	O54790	Gene names	Mafg
Domain Architecture
Description	Transcription factor MafG (V-maf musculoaponeurotic fibrosarcoma oncogene homolog G).

MAF_HUMAN
θ value	0.813845 (rank : 68)	NC score	0.171429 (rank : 55)
Query Neighborhood Hits	122	Target Neighborhood Hits	97	Shared Neighborhood Hits	37
SwissProt Accessions	O75444, Q9UP93	Gene names	MAF
Domain Architecture
Description	Transcription factor Maf (Proto-oncogene c-maf).

MYH11_MOUSE
θ value	0.813845 (rank : 69)	NC score	0.031347 (rank : 104)
Query Neighborhood Hits	122	Target Neighborhood Hits	1777	Shared Neighborhood Hits	53
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

TRIM8_HUMAN
θ value	0.813845 (rank : 70)	NC score	0.041121 (rank : 94)
Query Neighborhood Hits	122	Target Neighborhood Hits	650	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

CASC3_MOUSE
θ value	1.06291 (rank : 71)	NC score	0.032860 (rank : 101)
Query Neighborhood Hits	122	Target Neighborhood Hits	333	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

CCD41_HUMAN
θ value	1.06291 (rank : 72)	NC score	0.045632 (rank : 89)
Query Neighborhood Hits	122	Target Neighborhood Hits	1139	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

DC1L2_MOUSE
θ value	1.06291 (rank : 73)	NC score	0.022198 (rank : 118)
Query Neighborhood Hits	122	Target Neighborhood Hits	173	Shared Neighborhood Hits	6
SwissProt Accessions	Q6PDL0	Gene names	Dync1li2, Dncli2, Dnclic2
Domain Architecture	No domain graphic available
Description	Cytoplasmic dynein 1 light intermediate chain 2 (Dynein light intermediate chain 2, cytosolic).

GOGA6_HUMAN
θ value	1.06291 (rank : 74)	NC score	0.047622 (rank : 86)
Query Neighborhood Hits	122	Target Neighborhood Hits	1007	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

RABE1_MOUSE
θ value	1.06291 (rank : 75)	NC score	0.046183 (rank : 88)
Query Neighborhood Hits	122	Target Neighborhood Hits	1105	Shared Neighborhood Hits	46
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

JIP3_HUMAN
θ value	1.38821 (rank : 76)	NC score	0.036612 (rank : 100)
Query Neighborhood Hits	122	Target Neighborhood Hits	1039	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

KNTC2_MOUSE
θ value	1.38821 (rank : 77)	NC score	0.054522 (rank : 83)
Query Neighborhood Hits	122	Target Neighborhood Hits	692	Shared Neighborhood Hits	34
SwissProt Accessions	Q9D0F1, Q3TQT6, Q3UWM5, Q99P70	Gene names	Kntc2, Hec1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (Kinetochore-associated protein 2).

TPR_HUMAN
θ value	1.38821 (rank : 78)	NC score	0.032439 (rank : 103)
Query Neighborhood Hits	122	Target Neighborhood Hits	1921	Shared Neighborhood Hits	54
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

WBP1_MOUSE
θ value	1.38821 (rank : 79)	NC score	0.027633 (rank : 111)
Query Neighborhood Hits	122	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	P97764, Q8WUP5, Q99J20	Gene names	Wbp1
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 1 (WBP-1).

ATF5_MOUSE
θ value	1.81305 (rank : 80)	NC score	0.144417 (rank : 61)
Query Neighborhood Hits	122	Target Neighborhood Hits	62	Shared Neighborhood Hits	15
SwissProt Accessions	O70191, Q58E51, Q99NH6	Gene names	Atf5, Atfx, Nap1
Domain Architecture	No domain graphic available
Description	Cyclic AMP-dependent transcription factor ATF-5 (Activating transcription factor 5-alpha/beta) (Transcription factor ATFx) (Transcription factor-like protein ODA-10) (BZIP protein ATF7) (NRIF3- associated protein) (NAP1).

EYA3_HUMAN
θ value	1.81305 (rank : 81)	NC score	0.019471 (rank : 119)
Query Neighborhood Hits	122	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	Q99504, O95463, Q99813	Gene names	EYA3
Domain Architecture
Description	Eyes absent homolog 3 (EC 3.1.3.48).

FOXK2_HUMAN
θ value	1.81305 (rank : 82)	NC score	0.008184 (rank : 132)
Query Neighborhood Hits	122	Target Neighborhood Hits	190	Shared Neighborhood Hits	3
SwissProt Accessions	Q01167, Q13622, Q13623, Q13624	Gene names	FOXK2, ILF, ILF1
Domain Architecture
Description	Forkhead box protein K2 (Interleukin enhancer-binding factor 1) (Cellular transcription factor ILF-1).

GOGB1_HUMAN
θ value	1.81305 (rank : 83)	NC score	0.036820 (rank : 98)
Query Neighborhood Hits	122	Target Neighborhood Hits	2297	Shared Neighborhood Hits	65
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

MAF_MOUSE
θ value	1.81305 (rank : 84)	NC score	0.169897 (rank : 56)
Query Neighborhood Hits	122	Target Neighborhood Hits	95	Shared Neighborhood Hits	37
SwissProt Accessions	P54843	Gene names	Maf, Maf2
Domain Architecture
Description	Transcription factor Maf (Proto-oncogene c-maf).

MYH11_HUMAN
θ value	1.81305 (rank : 85)	NC score	0.029756 (rank : 109)
Query Neighborhood Hits	122	Target Neighborhood Hits	1806	Shared Neighborhood Hits	59
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH8_MOUSE
θ value	1.81305 (rank : 86)	NC score	0.025528 (rank : 114)
Query Neighborhood Hits	122	Target Neighborhood Hits	1600	Shared Neighborhood Hits	42
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

RABE1_HUMAN
θ value	1.81305 (rank : 87)	NC score	0.043942 (rank : 93)
Query Neighborhood Hits	122	Target Neighborhood Hits	1104	Shared Neighborhood Hits	45
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

TMC1_HUMAN
θ value	1.81305 (rank : 88)	NC score	0.050821 (rank : 85)
Query Neighborhood Hits	122	Target Neighborhood Hits	125	Shared Neighborhood Hits	14
SwissProt Accessions	Q8TDI8	Gene names	TMC1
Domain Architecture	No domain graphic available
Description	Transmembrane cochlear-expressed protein 1.

TSH1_HUMAN
θ value	1.81305 (rank : 89)	NC score	0.011141 (rank : 129)
Query Neighborhood Hits	122	Target Neighborhood Hits	558	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZSZ6, O60534, Q4LE29, Q53EU4	Gene names	TSHZ1, SDCCAG33, TSH1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3) (Antigen NY-CO-33).

BARH1_HUMAN
θ value	2.36792 (rank : 90)	NC score	0.003232 (rank : 133)
Query Neighborhood Hits	122	Target Neighborhood Hits	373	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BZE3, Q9NY88	Gene names	BARHL1
Domain Architecture
Description	BarH-like 1 homeobox protein.

CEBPE_MOUSE
θ value	2.36792 (rank : 91)	NC score	0.137924 (rank : 64)
Query Neighborhood Hits	122	Target Neighborhood Hits	108	Shared Neighborhood Hits	28
SwissProt Accessions	Q6PZD9	Gene names	Cebpe
Domain Architecture	No domain graphic available
Description	CCAAT/enhancer-binding protein epsilon (C/EBP epsilon).

MD1L1_MOUSE
θ value	2.36792 (rank : 92)	NC score	0.037492 (rank : 96)
Query Neighborhood Hits	122	Target Neighborhood Hits	1001	Shared Neighborhood Hits	39
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

RFIP5_MOUSE
θ value	2.36792 (rank : 93)	NC score	0.019045 (rank : 120)
Query Neighborhood Hits	122	Target Neighborhood Hits	126	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R361	Gene names	Rab11fip5, D6Ertd32e, Rip11
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 5 (Rab11-FIP5) (Rab11-interacting protein Rip11).

ZN488_HUMAN
θ value	2.36792 (rank : 94)	NC score	0.014922 (rank : 124)
Query Neighborhood Hits	122	Target Neighborhood Hits	484	Shared Neighborhood Hits	3
SwissProt Accessions	Q96MN9	Gene names	ZNF488
Domain Architecture	No domain graphic available
Description	Zinc finger protein 488.

ZN687_HUMAN
θ value	2.36792 (rank : 95)	NC score	0.002556 (rank : 134)
Query Neighborhood Hits	122	Target Neighborhood Hits	1244	Shared Neighborhood Hits	14
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

CDT1_HUMAN
θ value	3.0926 (rank : 96)	NC score	0.032470 (rank : 102)
Query Neighborhood Hits	122	Target Neighborhood Hits	92	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H211, Q86XX9, Q96CJ5, Q96GK5, Q96H67, Q96HE6, Q9BWM0	Gene names	CDT1
Domain Architecture	No domain graphic available
Description	DNA replication factor Cdt1 (Double parked homolog) (DUP).

MAFF_HUMAN
θ value	3.0926 (rank : 97)	NC score	0.142033 (rank : 63)
Query Neighborhood Hits	122	Target Neighborhood Hits	54	Shared Neighborhood Hits	29
SwissProt Accessions	Q9ULX9, Q9Y525	Gene names	MAFF
Domain Architecture
Description	Transcription factor MafF (V-maf musculoaponeurotic fibrosarcoma oncogene homolog F) (U-Maf).

MAFF_MOUSE
θ value	3.0926 (rank : 98)	NC score	0.145229 (rank : 60)
Query Neighborhood Hits	122	Target Neighborhood Hits	53	Shared Neighborhood Hits	31
SwissProt Accessions	O54791	Gene names	Maff
Domain Architecture
Description	Transcription factor MafF (V-maf musculoaponeurotic fibrosarcoma oncogene homolog F).

REN3B_HUMAN
θ value	3.0926 (rank : 99)	NC score	0.044027 (rank : 92)
Query Neighborhood Hits	122	Target Neighborhood Hits	412	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BZI7, Q9H1J0	Gene names	UPF3B, RENT3B, UPF3X
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3B (Nonsense mRNA reducing factor 3B) (Up-frameshift suppressor 3 homolog B) (hUpf3B) (hUpf3p-X).

RGS3_HUMAN
θ value	3.0926 (rank : 100)	NC score	0.011750 (rank : 128)
Query Neighborhood Hits	122	Target Neighborhood Hits	1375	Shared Neighborhood Hits	16
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

BAZ1A_HUMAN
θ value	4.03905 (rank : 101)	NC score	0.030659 (rank : 106)
Query Neighborhood Hits	122	Target Neighborhood Hits	693	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

DPOE1_HUMAN
θ value	4.03905 (rank : 102)	NC score	0.024611 (rank : 115)
Query Neighborhood Hits	122	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q07864, Q13533, Q86VH9	Gene names	POLE, POLE1
Domain Architecture
Description	DNA polymerase epsilon, catalytic subunit A (EC 2.7.7.7) (DNA polymerase II subunit A).

MY18A_MOUSE
θ value	4.03905 (rank : 103)	NC score	0.030997 (rank : 105)
Query Neighborhood Hits	122	Target Neighborhood Hits	1989	Shared Neighborhood Hits	56
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

OGFR_HUMAN
θ value	4.03905 (rank : 104)	NC score	0.009132 (rank : 130)
Query Neighborhood Hits	122	Target Neighborhood Hits	1582	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

BEGIN_MOUSE
θ value	5.27518 (rank : 105)	NC score	0.026249 (rank : 112)
Query Neighborhood Hits	122	Target Neighborhood Hits	383	Shared Neighborhood Hits	27
SwissProt Accessions	Q68EF6	Gene names	Begain
Domain Architecture	No domain graphic available
Description	Brain-enriched guanylate kinase-associated protein.

BSN_MOUSE
θ value	5.27518 (rank : 106)	NC score	0.026229 (rank : 113)
Query Neighborhood Hits	122	Target Neighborhood Hits	2057	Shared Neighborhood Hits	43
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

DPOE1_MOUSE
θ value	5.27518 (rank : 107)	NC score	0.023904 (rank : 116)
Query Neighborhood Hits	122	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WVF7, Q9QX50	Gene names	Pole, Pole1
Domain Architecture
Description	DNA polymerase epsilon, catalytic subunit A (EC 2.7.7.7) (DNA polymerase II subunit A).

JIP3_MOUSE
θ value	5.27518 (rank : 108)	NC score	0.030415 (rank : 108)
Query Neighborhood Hits	122	Target Neighborhood Hits	759	Shared Neighborhood Hits	30
SwissProt Accessions	Q9ESN9, Q99KU7, Q9EQD8, Q9ESN7, Q9ESN8, Q9ESP0, Q9JLH2, Q9JLH3, Q9R0U7	Gene names	Mapk8ip3, Jip3, Jsap1, Syd2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3) (JNK/SAPK-associated protein 1) (JSAP1) (Sunday driver 2).

MRCKB_HUMAN
θ value	5.27518 (rank : 109)	NC score	0.015239 (rank : 123)
Query Neighborhood Hits	122	Target Neighborhood Hits	2239	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

RTN1_MOUSE
θ value	5.27518 (rank : 110)	NC score	0.013924 (rank : 125)
Query Neighborhood Hits	122	Target Neighborhood Hits	189	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K0T0, Q8K4S4	Gene names	Rtn1, Nsp
Domain Architecture	No domain graphic available
Description	Reticulon-1 (Neuroendocrine-specific protein).

TEF_HUMAN
θ value	5.27518 (rank : 111)	NC score	0.103036 (rank : 69)
Query Neighborhood Hits	122	Target Neighborhood Hits	70	Shared Neighborhood Hits	25
SwissProt Accessions	Q10587, Q15729, Q7Z3J7, Q8IU94, Q96TG4	Gene names	TEF
Domain Architecture
Description	Thyrotroph embryonic factor.

TEF_MOUSE
θ value	5.27518 (rank : 112)	NC score	0.103177 (rank : 68)
Query Neighborhood Hits	122	Target Neighborhood Hits	68	Shared Neighborhood Hits	25
SwissProt Accessions	Q9JLC6, Q3U426, Q3UGF4, Q3UM49, Q3URC8, Q6QHT6, Q8C6I0, Q8VD02	Gene names	Tef
Domain Architecture	No domain graphic available
Description	Thyrotroph embryonic factor.

BSN_HUMAN
θ value	6.88961 (rank : 113)	NC score	0.029697 (rank : 110)
Query Neighborhood Hits	122	Target Neighborhood Hits	1537	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CROCC_MOUSE
θ value	6.88961 (rank : 114)	NC score	0.030653 (rank : 107)
Query Neighborhood Hits	122	Target Neighborhood Hits	1460	Shared Neighborhood Hits	48
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

DAAM2_MOUSE
θ value	6.88961 (rank : 115)	NC score	0.018980 (rank : 121)
Query Neighborhood Hits	122	Target Neighborhood Hits	371	Shared Neighborhood Hits	21
SwissProt Accessions	Q80U19, Q810J5	Gene names	Daam2, Kiaa0381
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 2.

HOOK3_HUMAN
θ value	6.88961 (rank : 116)	NC score	0.036736 (rank : 99)
Query Neighborhood Hits	122	Target Neighborhood Hits	1070	Shared Neighborhood Hits	60
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

CUBN_HUMAN
θ value	8.99809 (rank : 117)	NC score	-0.000685 (rank : 135)
Query Neighborhood Hits	122	Target Neighborhood Hits	482	Shared Neighborhood Hits	2
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

K0552_HUMAN
θ value	8.99809 (rank : 118)	NC score	0.037377 (rank : 97)
Query Neighborhood Hits	122	Target Neighborhood Hits	442	Shared Neighborhood Hits	29
SwissProt Accessions	O60299	Gene names	KIAA0552
Domain Architecture
Description	Protein KIAA0552.

MYH8_HUMAN
θ value	8.99809 (rank : 119)	NC score	0.022566 (rank : 117)
Query Neighborhood Hits	122	Target Neighborhood Hits	1610	Shared Neighborhood Hits	44
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

RIMB1_MOUSE
θ value	8.99809 (rank : 120)	NC score	0.037575 (rank : 95)
Query Neighborhood Hits	122	Target Neighborhood Hits	1376	Shared Neighborhood Hits	38
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

TCGAP_HUMAN
θ value	8.99809 (rank : 121)	NC score	0.008724 (rank : 131)
Query Neighborhood Hits	122	Target Neighborhood Hits	872	Shared Neighborhood Hits	14
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TSNA1_HUMAN
θ value	8.99809 (rank : 122)	NC score	0.013025 (rank : 126)
Query Neighborhood Hits	122	Target Neighborhood Hits	178	Shared Neighborhood Hits	10
SwissProt Accessions	Q96NA8	Gene names	TSNARE1
Domain Architecture	No domain graphic available
Description	t-SNARE domain-containing protein 1.

ATF4_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.076404 (rank : 76)
Query Neighborhood Hits	122	Target Neighborhood Hits	110	Shared Neighborhood Hits	28
SwissProt Accessions	P18848, Q9UH31	Gene names	ATF4
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-4 (Activating transcription factor 4) (DNA-binding protein TAXREB67) (Cyclic AMP response element-binding protein 2) (CREB2).

ATF4_MOUSE
θ value	θ > 10 (rank : 124)	NC score	0.082435 (rank : 73)
Query Neighborhood Hits	122	Target Neighborhood Hits	102	Shared Neighborhood Hits	30
SwissProt Accessions	Q06507, Q61906	Gene names	Atf4
Domain Architecture	No domain graphic available
Description	Cyclic AMP-dependent transcription factor ATF-4 (C/EBP-related ATF) (C/ATF) (TAXREB67 homolog).

ATF6B_HUMAN
θ value	θ > 10 (rank : 125)	NC score	0.100248 (rank : 70)
Query Neighborhood Hits	122	Target Neighborhood Hits	122	Shared Neighborhood Hits	26
SwissProt Accessions	Q99941, Q13269, Q14343, Q14345, Q99635, Q99637, Q9H3V9, Q9H3W1, Q9NPL0	Gene names	CREBL1, G13
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp) (Protein G13).

ATF6B_MOUSE
θ value	θ > 10 (rank : 126)	NC score	0.092316 (rank : 71)
Query Neighborhood Hits	122	Target Neighborhood Hits	97	Shared Neighborhood Hits	26
SwissProt Accessions	O35451	Gene names	Crebl1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp).

CAF1A_HUMAN
θ value	θ > 10 (rank : 127)	NC score	0.051624 (rank : 84)
Query Neighborhood Hits	122	Target Neighborhood Hits	750	Shared Neighborhood Hits	40
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CEBPA_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.077275 (rank : 75)
Query Neighborhood Hits	122	Target Neighborhood Hits	99	Shared Neighborhood Hits	24
SwissProt Accessions	P49715, P78319	Gene names	CEBPA
Domain Architecture
Description	CCAAT/enhancer-binding protein alpha (C/EBP alpha).

CEBPA_MOUSE
θ value	θ > 10 (rank : 129)	NC score	0.077699 (rank : 74)
Query Neighborhood Hits	122	Target Neighborhood Hits	86	Shared Neighborhood Hits	24
SwissProt Accessions	P53566, Q91XB6	Gene names	Cebpa
Domain Architecture
Description	CCAAT/enhancer-binding protein alpha (C/EBP alpha).

CEBPB_HUMAN
θ value	θ > 10 (rank : 130)	NC score	0.119934 (rank : 66)
Query Neighborhood Hits	122	Target Neighborhood Hits	141	Shared Neighborhood Hits	38
SwissProt Accessions	P17676, Q96IH2, Q9H4Z5	Gene names	CEBPB, TCF5
Domain Architecture
Description	CCAAT/enhancer-binding protein beta (C/EBP beta) (Nuclear factor NF- IL6) (Transcription factor 5).

CEBPB_MOUSE
θ value	θ > 10 (rank : 131)	NC score	0.119046 (rank : 67)
Query Neighborhood Hits	122	Target Neighborhood Hits	101	Shared Neighborhood Hits	34
SwissProt Accessions	P28033	Gene names	Cebpb
Domain Architecture
Description	CCAAT/enhancer-binding protein beta (C/EBP beta) (Interleukin-6- dependent-binding protein) (IL-6DBP) (Liver-enriched transcriptional activator) (LAP) (AGP/EBP).

CEBPD_HUMAN
θ value	θ > 10 (rank : 132)	NC score	0.143731 (rank : 62)
Query Neighborhood Hits	122	Target Neighborhood Hits	135	Shared Neighborhood Hits	33
SwissProt Accessions	P49716, Q14937	Gene names	CEBPD
Domain Architecture
Description	CCAAT/enhancer-binding protein delta (C/EBP delta) (Nuclear factor NF- IL6-beta) (NF-IL6-beta).

CEBPD_MOUSE
θ value	θ > 10 (rank : 133)	NC score	0.131114 (rank : 65)
Query Neighborhood Hits	122	Target Neighborhood Hits	90	Shared Neighborhood Hits	27
SwissProt Accessions	Q00322	Gene names	Cebpd, Crp3
Domain Architecture
Description	CCAAT/enhancer-binding protein delta (C/EBP delta) (C/EBP-related protein 3).

DBP_HUMAN
θ value	θ > 10 (rank : 134)	NC score	0.069805 (rank : 79)
Query Neighborhood Hits	122	Target Neighborhood Hits	136	Shared Neighborhood Hits	27
SwissProt Accessions	Q10586	Gene names	DBP
Domain Architecture
Description	D site-binding protein (Albumin D box-binding protein) (Albumin D- element-binding protein) (TAXREB302).

DBP_MOUSE
θ value	θ > 10 (rank : 135)	NC score	0.068713 (rank : 80)
Query Neighborhood Hits	122	Target Neighborhood Hits	137	Shared Neighborhood Hits	26
SwissProt Accessions	Q60925, Q8VCX3	Gene names	Dbp
Domain Architecture
Description	D site-binding protein (Albumin D box-binding protein) (Albumin D- element-binding protein).

Hits sorted by NC score

JUND_HUMAN
NC score	0.999962 (rank : 1)	θ value	3.66817e-102 (rank : 1)
Query Neighborhood Hits	122	Target Neighborhood Hits	122	Shared Neighborhood Hits	122
SwissProt Accessions	P17535	Gene names	JUND
Domain Architecture
Description	Transcription factor jun-D.

JUND_MOUSE
NC score	0.988016 (rank : 2)	θ value	7.15887e-98 (rank : 2)
Query Neighborhood Hits	122	Target Neighborhood Hits	134	Shared Neighborhood Hits	103
SwissProt Accessions	P15066	Gene names	Jund, Jun-d, Jund1
Domain Architecture
Description	Transcription factor jun-D.

JUN_MOUSE
NC score	0.962914 (rank : 3)	θ value	1.6097e-65 (rank : 4)
Query Neighborhood Hits	122	Target Neighborhood Hits	145	Shared Neighborhood Hits	87
SwissProt Accessions	P05627	Gene names	Jun
Domain Architecture
Description	Transcription factor AP-1 (Activator protein 1) (AP1) (Proto-oncogene c-jun) (V-jun avian sarcoma virus 17 oncogene homolog) (Jun A) (AH119).

JUN_HUMAN
NC score	0.961562 (rank : 4)	θ value	1.2325e-65 (rank : 3)
Query Neighborhood Hits	122	Target Neighborhood Hits	144	Shared Neighborhood Hits	87
SwissProt Accessions	P05412, Q96G93	Gene names	JUN
Domain Architecture
Description	Transcription factor AP-1 (Activator protein 1) (AP1) (Proto-oncogene c-jun) (V-jun avian sarcoma virus 17 oncogene homolog) (p39).

JUNB_HUMAN
NC score	0.920455 (rank : 5)	θ value	3.4976e-36 (rank : 6)
Query Neighborhood Hits	122	Target Neighborhood Hits	97	Shared Neighborhood Hits	65
SwissProt Accessions	P17275, Q96GH3	Gene names	JUNB
Domain Architecture
Description	Transcription factor jun-B.

JUNB_MOUSE
NC score	0.920066 (rank : 6)	θ value	3.2585e-50 (rank : 5)
Query Neighborhood Hits	122	Target Neighborhood Hits	116	Shared Neighborhood Hits	64
SwissProt Accessions	P09450, Q8C2G9	Gene names	Junb, Jun-b
Domain Architecture
Description	Transcription factor jun-B.

CREB5_HUMAN
NC score	0.534717 (rank : 7)	θ value	7.59969e-07 (rank : 11)
Query Neighborhood Hits	122	Target Neighborhood Hits	222	Shared Neighborhood Hits	45
SwissProt Accessions	Q02930, Q05886, Q06246	Gene names	CREB5, CREBPA
Domain Architecture
Description	cAMP response element-binding protein 5 (CRE-BPa).

ATF7_MOUSE
NC score	0.514808 (rank : 8)	θ value	1.25267e-09 (rank : 8)
Query Neighborhood Hits	122	Target Neighborhood Hits	286	Shared Neighborhood Hits	51
SwissProt Accessions	Q8R0S1	Gene names	Atf7
Domain Architecture	No domain graphic available
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

ATF7_HUMAN
NC score	0.509931 (rank : 9)	θ value	1.25267e-09 (rank : 7)
Query Neighborhood Hits	122	Target Neighborhood Hits	333	Shared Neighborhood Hits	52
SwissProt Accessions	P17544, Q13814	Gene names	ATF7, ATFA
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

ATF3_HUMAN
NC score	0.489201 (rank : 10)	θ value	0.00035302 (rank : 20)
Query Neighborhood Hits	122	Target Neighborhood Hits	120	Shared Neighborhood Hits	62
SwissProt Accessions	P18847	Gene names	ATF3
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-3 (Activating transcription factor 3).

ATF2_HUMAN
NC score	0.481242 (rank : 11)	θ value	8.97725e-08 (rank : 9)
Query Neighborhood Hits	122	Target Neighborhood Hits	402	Shared Neighborhood Hits	50
SwissProt Accessions	P15336, Q13000	Gene names	ATF2, CREB2, CREBP1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (HB16).

ATF2_MOUSE
NC score	0.480526 (rank : 12)	θ value	1.17247e-07 (rank : 10)
Query Neighborhood Hits	122	Target Neighborhood Hits	397	Shared Neighborhood Hits	50
SwissProt Accessions	P16951, Q64089, Q64090, Q64091	Gene names	Atf2
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (MXBP protein).

ATF3_MOUSE
NC score	0.471120 (rank : 13)	θ value	0.00175202 (rank : 29)
Query Neighborhood Hits	122	Target Neighborhood Hits	120	Shared Neighborhood Hits	61
SwissProt Accessions	Q60765	Gene names	Atf3
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-3 (Activating transcription factor 3) (Transcription factor LRG-21).

BATF_HUMAN
NC score	0.446665 (rank : 14)	θ value	0.00035302 (rank : 21)
Query Neighborhood Hits	122	Target Neighborhood Hits	80	Shared Neighborhood Hits	47
SwissProt Accessions	Q16520	Gene names	BATF
Domain Architecture
Description	ATF-like basic leucine zipper transcriptional factor B-ATF (SF-HT- activated gene 2) (SFA-2).

BATF_MOUSE
NC score	0.440941 (rank : 15)	θ value	0.000270298 (rank : 19)
Query Neighborhood Hits	122	Target Neighborhood Hits	100	Shared Neighborhood Hits	52
SwissProt Accessions	O35284	Gene names	Batf
Domain Architecture
Description	ATF-like basic leucine zipper transcription factor B-ATF.

FOSB_MOUSE
NC score	0.428834 (rank : 16)	θ value	0.00020696 (rank : 17)
Query Neighborhood Hits	122	Target Neighborhood Hits	137	Shared Neighborhood Hits	47
SwissProt Accessions	P13346	Gene names	Fosb
Domain Architecture	No domain graphic available
Description	Protein fosB.

FOSB_HUMAN
NC score	0.427848 (rank : 17)	θ value	0.00020696 (rank : 16)
Query Neighborhood Hits	122	Target Neighborhood Hits	141	Shared Neighborhood Hits	47
SwissProt Accessions	P53539	Gene names	FOSB, G0S3
Domain Architecture	No domain graphic available
Description	Protein fosB (G0/G1 switch regulatory protein 3).

NFE2_HUMAN
NC score	0.397441 (rank : 18)	θ value	7.1131e-05 (rank : 14)
Query Neighborhood Hits	122	Target Neighborhood Hits	66	Shared Neighborhood Hits	29
SwissProt Accessions	Q16621, Q07720, Q6ICV9	Gene names	NFE2
Domain Architecture	No domain graphic available
Description	Transcription factor NF-E2 45 kDa subunit (Nuclear factor, erythroid- derived 2 45 kDa subunit) (p45 NF-E2) (Leucine zipper protein NF-E2).

FOSL1_MOUSE
NC score	0.383676 (rank : 19)	θ value	0.0736092 (rank : 45)
Query Neighborhood Hits	122	Target Neighborhood Hits	113	Shared Neighborhood Hits	43
SwissProt Accessions	P48755, O35285	Gene names	Fosl1, Fra1
Domain Architecture
Description	Fos-related antigen 1 (FRA-1).

FOSL2_HUMAN
NC score	0.379112 (rank : 20)	θ value	0.00298849 (rank : 34)
Query Neighborhood Hits	122	Target Neighborhood Hits	158	Shared Neighborhood Hits	46
SwissProt Accessions	P15408	Gene names	FOSL2, FRA2
Domain Architecture	No domain graphic available
Description	Fos-related antigen 2.

FOSL1_HUMAN
NC score	0.376844 (rank : 21)	θ value	0.0736092 (rank : 44)
Query Neighborhood Hits	122	Target Neighborhood Hits	112	Shared Neighborhood Hits	45
SwissProt Accessions	P15407	Gene names	FOSL1, FRA1
Domain Architecture
Description	Fos-related antigen 1 (FRA-1).

CREB3_MOUSE
NC score	0.374580 (rank : 22)	θ value	0.00869519 (rank : 41)
Query Neighborhood Hits	122	Target Neighborhood Hits	97	Shared Neighborhood Hits	51
SwissProt Accessions	Q61817, Q99M21, Q9CVK9	Gene names	Creb3, Lzip
Domain Architecture	No domain graphic available
Description	Cyclic AMP-responsive element-binding protein 3 (Transcription factor LZIP).

NF2L1_HUMAN
NC score	0.373445 (rank : 23)	θ value	0.000602161 (rank : 24)
Query Neighborhood Hits	122	Target Neighborhood Hits	169	Shared Neighborhood Hits	60
SwissProt Accessions	Q14494, Q12877, Q96FN6	Gene names	NFE2L1, HBZ17, NRF1, TCF11
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 1 (NF-E2-related factor 1) (NFE2-related factor 1) (Nuclear factor, erythroid derived 2, like 1) (Transcription factor 11) (Transcription factor HBZ17) (Transcription factor LCR-F1) (Locus control region-factor 1).

FOSL2_MOUSE
NC score	0.370044 (rank : 24)	θ value	0.00665767 (rank : 38)
Query Neighborhood Hits	122	Target Neighborhood Hits	151	Shared Neighborhood Hits	47
SwissProt Accessions	P47930	Gene names	Fosl2, Fra-2, Fra2
Domain Architecture	No domain graphic available
Description	Fos-related antigen 2.

NF2L1_MOUSE
NC score	0.369866 (rank : 25)	θ value	0.000602161 (rank : 25)
Query Neighborhood Hits	122	Target Neighborhood Hits	185	Shared Neighborhood Hits	61
SwissProt Accessions	Q61985, O70234	Gene names	Nfe2l1, Nrf1
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 1 (NF-E2-related factor 1) (NFE2-related factor 1) (Nuclear factor, erythroid derived 2, like 1).

XBP1_MOUSE
NC score	0.369558 (rank : 26)	θ value	0.00020696 (rank : 18)
Query Neighborhood Hits	122	Target Neighborhood Hits	99	Shared Neighborhood Hits	46
SwissProt Accessions	O35426, Q8VHM0, Q922G5, Q9ESS3	Gene names	Xbp1, Treb5
Domain Architecture	No domain graphic available
Description	X box-binding protein 1 (XBP-1) (Tax-responsive element-binding protein 5 homolog).

NF2L3_MOUSE
NC score	0.364766 (rank : 27)	θ value	0.000602161 (rank : 26)
Query Neighborhood Hits	122	Target Neighborhood Hits	93	Shared Neighborhood Hits	46
SwissProt Accessions	Q9WTM4	Gene names	Nfe2l3, Nrf3
Domain Architecture	No domain graphic available
Description	Nuclear factor erythroid 2-related factor 3 (NF-E2-related factor 3) (NFE2-related factor 3) (Nuclear factor, erythroid derived 2, like 3).

XBP1_HUMAN
NC score	0.360668 (rank : 28)	θ value	0.000158464 (rank : 15)
Query Neighborhood Hits	122	Target Neighborhood Hits	109	Shared Neighborhood Hits	39
SwissProt Accessions	P17861, Q8WYK6, Q969P1, Q96BD7	Gene names	XBP1, TREB5, XBP2
Domain Architecture	No domain graphic available
Description	X box-binding protein 1 (XBP-1) (Tax-responsive element-binding protein 5).

NF2L2_MOUSE
NC score	0.353757 (rank : 29)	θ value	0.00665767 (rank : 39)
Query Neighborhood Hits	122	Target Neighborhood Hits	183	Shared Neighborhood Hits	60
SwissProt Accessions	Q60795	Gene names	Nfe2l2, Nrf-2, Nrf2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2).

CREB3_HUMAN
NC score	0.353432 (rank : 30)	θ value	0.00298849 (rank : 31)
Query Neighborhood Hits	122	Target Neighborhood Hits	138	Shared Neighborhood Hits	44
SwissProt Accessions	O43889, O14671, O14919, Q96GK8, Q9H2W3, Q9UE77	Gene names	CREB3, LZIP
Domain Architecture	No domain graphic available
Description	Cyclic AMP-responsive element-binding protein 3 (Luman protein) (Transcription factor LZIP-alpha).

NF2L3_HUMAN
NC score	0.348617 (rank : 31)	θ value	0.00298849 (rank : 35)
Query Neighborhood Hits	122	Target Neighborhood Hits	150	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y4A8, Q6NUS0, Q7Z498, Q86UJ4, Q86VR5, Q9UQA4	Gene names	NFE2L3, NRF3
Domain Architecture	No domain graphic available
Description	Nuclear factor erythroid 2-related factor 3 (NF-E2-related factor 3) (NFE2-related factor 3) (Nuclear factor, erythroid derived 2, like 3).

NF2L2_HUMAN
NC score	0.332501 (rank : 32)	θ value	0.00102713 (rank : 28)
Query Neighborhood Hits	122	Target Neighborhood Hits	109	Shared Neighborhood Hits	35
SwissProt Accessions	Q16236, Q96F71	Gene names	NFE2L2, NRF2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2) (HEBP1).

FOS_MOUSE
NC score	0.331731 (rank : 33)	θ value	0.0961366 (rank : 47)
Query Neighborhood Hits	122	Target Neighborhood Hits	69	Shared Neighborhood Hits	39
SwissProt Accessions	P01101	Gene names	Fos
Domain Architecture
Description	Proto-oncogene protein c-fos (Cellular oncogene fos).

FOS_HUMAN
NC score	0.329630 (rank : 34)	θ value	0.0961366 (rank : 46)
Query Neighborhood Hits	122	Target Neighborhood Hits	72	Shared Neighborhood Hits	39
SwissProt Accessions	P01100, P18849	Gene names	FOS, G0S7
Domain Architecture
Description	Proto-oncogene protein c-fos (Cellular oncogene fos) (G0/G1 switch regulatory protein 7).

ATF1_HUMAN
NC score	0.327091 (rank : 35)	θ value	0.00298849 (rank : 30)
Query Neighborhood Hits	122	Target Neighborhood Hits	59	Shared Neighborhood Hits	33
SwissProt Accessions	P18846, P25168	Gene names	ATF1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-1 (Activating transcription factor 1) (TREB36 protein).

CREM_MOUSE
NC score	0.319823 (rank : 36)	θ value	0.00298849 (rank : 33)
Query Neighborhood Hits	122	Target Neighborhood Hits	58	Shared Neighborhood Hits	30
SwissProt Accessions	P27699, P27698	Gene names	Crem
Domain Architecture
Description	cAMP-responsive element modulator.

CREM_HUMAN
NC score	0.317931 (rank : 37)	θ value	0.00298849 (rank : 32)
Query Neighborhood Hits	122	Target Neighborhood Hits	63	Shared Neighborhood Hits	31
SwissProt Accessions	Q03060, Q16114, Q16116, Q9NZB9	Gene names	CREM
Domain Architecture
Description	cAMP-responsive element modulator.

ATF1_MOUSE
NC score	0.316667 (rank : 38)	θ value	0.00869519 (rank : 40)
Query Neighborhood Hits	122	Target Neighborhood Hits	70	Shared Neighborhood Hits	31
SwissProt Accessions	P81269	Gene names	Atf1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-1 (Activating transcription factor 1) (TCR-ATF1).

CREB1_MOUSE
NC score	0.298105 (rank : 39)	θ value	0.00665767 (rank : 37)
Query Neighborhood Hits	122	Target Neighborhood Hits	58	Shared Neighborhood Hits	30
SwissProt Accessions	Q01147	Gene names	Creb1, Creb-1
Domain Architecture
Description	cAMP response element-binding protein (CREB).

CREB1_HUMAN
NC score	0.298069 (rank : 40)	θ value	0.00665767 (rank : 36)
Query Neighborhood Hits	122	Target Neighborhood Hits	57	Shared Neighborhood Hits	30
SwissProt Accessions	P16220, P21934, Q9UMA7	Gene names	CREB1
Domain Architecture
Description	cAMP response element-binding protein (CREB).

BACH1_HUMAN
NC score	0.255109 (rank : 41)	θ value	3.19293e-05 (rank : 12)
Query Neighborhood Hits	122	Target Neighborhood Hits	289	Shared Neighborhood Hits	61
SwissProt Accessions	O14867, O43285	Gene names	BACH1
Domain Architecture
Description	Transcription regulator protein BACH1 (BTB and CNC homolog 1) (HA2303).

BACH1_MOUSE
NC score	0.250600 (rank : 42)	θ value	5.44631e-05 (rank : 13)
Query Neighborhood Hits	122	Target Neighborhood Hits	289	Shared Neighborhood Hits	60
SwissProt Accessions	P97302	Gene names	Bach1
Domain Architecture
Description	Transcription regulator protein BACH1 (BTB and CNC homolog 1).

ATF6A_HUMAN
NC score	0.233394 (rank : 43)	θ value	0.47712 (rank : 56)
Query Neighborhood Hits	122	Target Neighborhood Hits	174	Shared Neighborhood Hits	62
SwissProt Accessions	P18850, O15139, Q5VW62, Q6IPB5, Q9UEC9	Gene names	ATF6
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 alpha (Activating transcription factor 6 alpha) (ATF6-alpha).

BACH2_HUMAN
NC score	0.219211 (rank : 44)	θ value	0.000602161 (rank : 23)
Query Neighborhood Hits	122	Target Neighborhood Hits	234	Shared Neighborhood Hits	45
SwissProt Accessions	Q9BYV9, Q59H70, Q5T793, Q9NTS5	Gene names	BACH2
Domain Architecture
Description	Transcription regulator protein BACH2 (BTB and CNC homolog 2).

BACH2_MOUSE
NC score	0.217147 (rank : 45)	θ value	0.00102713 (rank : 27)
Query Neighborhood Hits	122	Target Neighborhood Hits	248	Shared Neighborhood Hits	46
SwissProt Accessions	P97303	Gene names	Bach2
Domain Architecture
Description	Transcription regulator protein BACH2 (BTB and CNC homolog 2).

CEBPE_HUMAN
NC score	0.197820 (rank : 46)	θ value	0.125558 (rank : 48)
Query Neighborhood Hits	122	Target Neighborhood Hits	236	Shared Neighborhood Hits	35
SwissProt Accessions	Q15744, Q15745, Q8IYI2, Q99803	Gene names	CEBPE
Domain Architecture
Description	CCAAT/enhancer-binding protein epsilon (C/EBP epsilon).

MAFG_HUMAN
NC score	0.183971 (rank : 47)	θ value	0.813845 (rank : 66)
Query Neighborhood Hits	122	Target Neighborhood Hits	85	Shared Neighborhood Hits	42
SwissProt Accessions	O15525	Gene names	MAFG
Domain Architecture
Description	Transcription factor MafG (V-maf musculoaponeurotic fibrosarcoma oncogene homolog G) (hMAF).

MAFB_MOUSE
NC score	0.183946 (rank : 48)	θ value	0.279714 (rank : 52)
Query Neighborhood Hits	122	Target Neighborhood Hits	92	Shared Neighborhood Hits	43
SwissProt Accessions	P54841	Gene names	Mafb, Krml, Maf1
Domain Architecture
Description	Transcription factor MafB (V-maf musculoaponeurotic fibrosarcoma oncogene homolog B) (Transcription factor MAF1) (Segmentation protein KR) (Kreisler).

MAFG_MOUSE
NC score	0.183542 (rank : 49)	θ value	0.813845 (rank : 67)
Query Neighborhood Hits	122	Target Neighborhood Hits	90	Shared Neighborhood Hits	42
SwissProt Accessions	O54790	Gene names	Mafg
Domain Architecture
Description	Transcription factor MafG (V-maf musculoaponeurotic fibrosarcoma oncogene homolog G).

MAFB_HUMAN
NC score	0.183290 (rank : 50)	θ value	0.279714 (rank : 51)
Query Neighborhood Hits	122	Target Neighborhood Hits	96	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y5Q3, Q9H1F1	Gene names	MAFB, KRML
Domain Architecture
Description	Transcription factor MafB (V-maf musculoaponeurotic fibrosarcoma oncogene homolog B).

MAFK_HUMAN
NC score	0.177880 (rank : 51)	θ value	0.62314 (rank : 61)
Query Neighborhood Hits	122	Target Neighborhood Hits	73	Shared Neighborhood Hits	37
SwissProt Accessions	O60675	Gene names	MAFK
Domain Architecture
Description	Transcription factor MafK (Erythroid transcription factor NF-E2 p18 subunit).

NRL_MOUSE
NC score	0.177546 (rank : 52)	θ value	0.62314 (rank : 64)
Query Neighborhood Hits	122	Target Neighborhood Hits	36	Shared Neighborhood Hits	30
SwissProt Accessions	P54846	Gene names	Nrl
Domain Architecture
Description	Neural retina-specific leucine zipper protein (NRL).

MAFK_MOUSE
NC score	0.177271 (rank : 53)	θ value	0.62314 (rank : 62)
Query Neighborhood Hits	122	Target Neighborhood Hits	73	Shared Neighborhood Hits	37
SwissProt Accessions	Q61827, Q60600	Gene names	Mafk, Nfe2u
Domain Architecture
Description	Transcription factor MafK (Erythroid transcription factor NF-E2 p18 subunit).

NRL_HUMAN
NC score	0.174270 (rank : 54)	θ value	0.62314 (rank : 63)
Query Neighborhood Hits	122	Target Neighborhood Hits	39	Shared Neighborhood Hits	29
SwissProt Accessions	P54845	Gene names	NRL
Domain Architecture
Description	Neural retina-specific leucine zipper protein (NRL) (D14S46E).

MAF_HUMAN
NC score	0.171429 (rank : 55)	θ value	0.813845 (rank : 68)
Query Neighborhood Hits	122	Target Neighborhood Hits	97	Shared Neighborhood Hits	37
SwissProt Accessions	O75444, Q9UP93	Gene names	MAF
Domain Architecture
Description	Transcription factor Maf (Proto-oncogene c-maf).

MAF_MOUSE
NC score	0.169897 (rank : 56)	θ value	1.81305 (rank : 84)
Query Neighborhood Hits	122	Target Neighborhood Hits	95	Shared Neighborhood Hits	37
SwissProt Accessions	P54843	Gene names	Maf, Maf2
Domain Architecture
Description	Transcription factor Maf (Proto-oncogene c-maf).

ATF5_HUMAN
NC score	0.169666 (rank : 57)	θ value	0.62314 (rank : 60)
Query Neighborhood Hits	122	Target Neighborhood Hits	99	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y2D1, Q9BSA1, Q9UNQ3	Gene names	ATF5, ATFX
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-5 (Activating transcription factor 5) (Transcription factor ATFx).

CEBPG_MOUSE
NC score	0.153349 (rank : 58)	θ value	0.0736092 (rank : 43)
Query Neighborhood Hits	122	Target Neighborhood Hits	77	Shared Neighborhood Hits	24
SwissProt Accessions	P53568	Gene names	Cebpg
Domain Architecture
Description	CCAAT/enhancer-binding protein gamma (C/EBP gamma) (Immunoglobulin enhancer-binding protein 1) (IG/EBP-1) (Granulocyte colony-stimulating factor promoter element 1-binding protein) (GPE1-binding protein) (GPE1-BP).

CEBPG_HUMAN
NC score	0.147234 (rank : 59)	θ value	0.163984 (rank : 49)
Query Neighborhood Hits	122	Target Neighborhood Hits	101	Shared Neighborhood Hits	26
SwissProt Accessions	P53567, Q5U052	Gene names	CEBPG
Domain Architecture
Description	CCAAT/enhancer-binding protein gamma (C/EBP gamma).

MAFF_MOUSE
NC score	0.145229 (rank : 60)	θ value	3.0926 (rank : 98)
Query Neighborhood Hits	122	Target Neighborhood Hits	53	Shared Neighborhood Hits	31
SwissProt Accessions	O54791	Gene names	Maff
Domain Architecture
Description	Transcription factor MafF (V-maf musculoaponeurotic fibrosarcoma oncogene homolog F).

ATF5_MOUSE
NC score	0.144417 (rank : 61)	θ value	1.81305 (rank : 80)
Query Neighborhood Hits	122	Target Neighborhood Hits	62	Shared Neighborhood Hits	15
SwissProt Accessions	O70191, Q58E51, Q99NH6	Gene names	Atf5, Atfx, Nap1
Domain Architecture	No domain graphic available
Description	Cyclic AMP-dependent transcription factor ATF-5 (Activating transcription factor 5-alpha/beta) (Transcription factor ATFx) (Transcription factor-like protein ODA-10) (BZIP protein ATF7) (NRIF3- associated protein) (NAP1).

CEBPD_HUMAN
NC score	0.143731 (rank : 62)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	122	Target Neighborhood Hits	135	Shared Neighborhood Hits	33
SwissProt Accessions	P49716, Q14937	Gene names	CEBPD
Domain Architecture
Description	CCAAT/enhancer-binding protein delta (C/EBP delta) (Nuclear factor NF- IL6-beta) (NF-IL6-beta).

MAFF_HUMAN
NC score	0.142033 (rank : 63)	θ value	3.0926 (rank : 97)
Query Neighborhood Hits	122	Target Neighborhood Hits	54	Shared Neighborhood Hits	29
SwissProt Accessions	Q9ULX9, Q9Y525	Gene names	MAFF
Domain Architecture
Description	Transcription factor MafF (V-maf musculoaponeurotic fibrosarcoma oncogene homolog F) (U-Maf).

CEBPE_MOUSE
NC score	0.137924 (rank : 64)	θ value	2.36792 (rank : 91)
Query Neighborhood Hits	122	Target Neighborhood Hits	108	Shared Neighborhood Hits	28
SwissProt Accessions	Q6PZD9	Gene names	Cebpe
Domain Architecture	No domain graphic available
Description	CCAAT/enhancer-binding protein epsilon (C/EBP epsilon).

CEBPD_MOUSE
NC score	0.131114 (rank : 65)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	122	Target Neighborhood Hits	90	Shared Neighborhood Hits	27
SwissProt Accessions	Q00322	Gene names	Cebpd, Crp3
Domain Architecture
Description	CCAAT/enhancer-binding protein delta (C/EBP delta) (C/EBP-related protein 3).

CEBPB_HUMAN
NC score	0.119934 (rank : 66)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	122	Target Neighborhood Hits	141	Shared Neighborhood Hits	38
SwissProt Accessions	P17676, Q96IH2, Q9H4Z5	Gene names	CEBPB, TCF5
Domain Architecture
Description	CCAAT/enhancer-binding protein beta (C/EBP beta) (Nuclear factor NF- IL6) (Transcription factor 5).

CEBPB_MOUSE
NC score	0.119046 (rank : 67)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	122	Target Neighborhood Hits	101	Shared Neighborhood Hits	34
SwissProt Accessions	P28033	Gene names	Cebpb
Domain Architecture
Description	CCAAT/enhancer-binding protein beta (C/EBP beta) (Interleukin-6- dependent-binding protein) (IL-6DBP) (Liver-enriched transcriptional activator) (LAP) (AGP/EBP).

TEF_MOUSE
NC score	0.103177 (rank : 68)	θ value	5.27518 (rank : 112)
Query Neighborhood Hits	122	Target Neighborhood Hits	68	Shared Neighborhood Hits	25
SwissProt Accessions	Q9JLC6, Q3U426, Q3UGF4, Q3UM49, Q3URC8, Q6QHT6, Q8C6I0, Q8VD02	Gene names	Tef
Domain Architecture	No domain graphic available
Description	Thyrotroph embryonic factor.

TEF_HUMAN
NC score	0.103036 (rank : 69)	θ value	5.27518 (rank : 111)
Query Neighborhood Hits	122	Target Neighborhood Hits	70	Shared Neighborhood Hits	25
SwissProt Accessions	Q10587, Q15729, Q7Z3J7, Q8IU94, Q96TG4	Gene names	TEF
Domain Architecture
Description	Thyrotroph embryonic factor.

ATF6B_HUMAN
NC score	0.100248 (rank : 70)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	122	Target Neighborhood Hits	122	Shared Neighborhood Hits	26
SwissProt Accessions	Q99941, Q13269, Q14343, Q14345, Q99635, Q99637, Q9H3V9, Q9H3W1, Q9NPL0	Gene names	CREBL1, G13
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp) (Protein G13).

ATF6B_MOUSE
NC score	0.092316 (rank : 71)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	122	Target Neighborhood Hits	97	Shared Neighborhood Hits	26
SwissProt Accessions	O35451	Gene names	Crebl1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp).

RFIP4_HUMAN
NC score	0.084004 (rank : 72)	θ value	0.0330416 (rank : 42)
Query Neighborhood Hits	122	Target Neighborhood Hits	785	Shared Neighborhood Hits	43
SwissProt Accessions	Q86YS3, Q8N829, Q8NDT7, Q969D8	Gene names	RAB11FIP4, KIAA1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

ATF4_MOUSE
NC score	0.082435 (rank : 73)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	122	Target Neighborhood Hits	102	Shared Neighborhood Hits	30
SwissProt Accessions	Q06507, Q61906	Gene names	Atf4
Domain Architecture	No domain graphic available
Description	Cyclic AMP-dependent transcription factor ATF-4 (C/EBP-related ATF) (C/ATF) (TAXREB67 homolog).

CEBPA_MOUSE
NC score	0.077699 (rank : 74)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	122	Target Neighborhood Hits	86	Shared Neighborhood Hits	24
SwissProt Accessions	P53566, Q91XB6	Gene names	Cebpa
Domain Architecture
Description	CCAAT/enhancer-binding protein alpha (C/EBP alpha).

CEBPA_HUMAN
NC score	0.077275 (rank : 75)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	122	Target Neighborhood Hits	99	Shared Neighborhood Hits	24
SwissProt Accessions	P49715, P78319	Gene names	CEBPA
Domain Architecture
Description	CCAAT/enhancer-binding protein alpha (C/EBP alpha).

ATF4_HUMAN
NC score	0.076404 (rank : 76)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	122	Target Neighborhood Hits	110	Shared Neighborhood Hits	28
SwissProt Accessions	P18848, Q9UH31	Gene names	ATF4
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-4 (Activating transcription factor 4) (DNA-binding protein TAXREB67) (Cyclic AMP response element-binding protein 2) (CREB2).

TNNT3_HUMAN
NC score	0.072504 (rank : 77)	θ value	0.365318 (rank : 54)
Query Neighborhood Hits	122	Target Neighborhood Hits	327	Shared Neighborhood Hits	21
SwissProt Accessions	P45378, Q12975, Q12976, Q12977, Q12978, Q86TH6	Gene names	TNNT3
Domain Architecture	No domain graphic available
Description	Troponin T, fast skeletal muscle (TnTf) (Fast skeletal muscle troponin T) (fTnT) (Beta TnTF).

NIPBL_HUMAN
NC score	0.069811 (rank : 78)	θ value	0.00035302 (rank : 22)
Query Neighborhood Hits	122	Target Neighborhood Hits	1311	Shared Neighborhood Hits	22
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

DBP_HUMAN
NC score	0.069805 (rank : 79)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	122	Target Neighborhood Hits	136	Shared Neighborhood Hits	27
SwissProt Accessions	Q10586	Gene names	DBP
Domain Architecture
Description	D site-binding protein (Albumin D box-binding protein) (Albumin D- element-binding protein) (TAXREB302).

DBP_MOUSE
NC score	0.068713 (rank : 80)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	122	Target Neighborhood Hits	137	Shared Neighborhood Hits	26
SwissProt Accessions	Q60925, Q8VCX3	Gene names	Dbp
Domain Architecture
Description	D site-binding protein (Albumin D box-binding protein) (Albumin D- element-binding protein).

RFIP4_MOUSE
NC score	0.067003 (rank : 81)	θ value	0.47712 (rank : 58)
Query Neighborhood Hits	122	Target Neighborhood Hits	708	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BQP8, Q80T87	Gene names	Rab11fip4, Kiaa1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

RIMB1_HUMAN
NC score	0.061857 (rank : 82)	θ value	0.365318 (rank : 53)
Query Neighborhood Hits	122	Target Neighborhood Hits	1479	Shared Neighborhood Hits	47
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

KNTC2_MOUSE
NC score	0.054522 (rank : 83)	θ value	1.38821 (rank : 77)
Query Neighborhood Hits	122	Target Neighborhood Hits	692	Shared Neighborhood Hits	34
SwissProt Accessions	Q9D0F1, Q3TQT6, Q3UWM5, Q99P70	Gene names	Kntc2, Hec1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (Kinetochore-associated protein 2).

CAF1A_HUMAN
NC score	0.051624 (rank : 84)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	122	Target Neighborhood Hits	750	Shared Neighborhood Hits	40
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

TMC1_HUMAN
NC score	0.050821 (rank : 85)	θ value	1.81305 (rank : 88)
Query Neighborhood Hits	122	Target Neighborhood Hits	125	Shared Neighborhood Hits	14
SwissProt Accessions	Q8TDI8	Gene names	TMC1
Domain Architecture	No domain graphic available
Description	Transmembrane cochlear-expressed protein 1.

GOGA6_HUMAN
NC score	0.047622 (rank : 86)	θ value	1.06291 (rank : 74)
Query Neighborhood Hits	122	Target Neighborhood Hits	1007	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

TBCD2_HUMAN
NC score	0.047549 (rank : 87)	θ value	0.47712 (rank : 59)
Query Neighborhood Hits	122	Target Neighborhood Hits	419	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

RABE1_MOUSE
NC score	0.046183 (rank : 88)	θ value	1.06291 (rank : 75)
Query Neighborhood Hits	122	Target Neighborhood Hits	1105	Shared Neighborhood Hits	46
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

CCD41_HUMAN
NC score	0.045632 (rank : 89)	θ value	1.06291 (rank : 72)
Query Neighborhood Hits	122	Target Neighborhood Hits	1139	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

TRIM8_MOUSE
NC score	0.044735 (rank : 90)	θ value	0.365318 (rank : 55)
Query Neighborhood Hits	122	Target Neighborhood Hits	674	Shared Neighborhood Hits	30
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

CCD41_MOUSE
NC score	0.044372 (rank : 91)	θ value	0.813845 (rank : 65)
Query Neighborhood Hits	122	Target Neighborhood Hits	1399	Shared Neighborhood Hits	51
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

REN3B_HUMAN
NC score	0.044027 (rank : 92)	θ value	3.0926 (rank : 99)
Query Neighborhood Hits	122	Target Neighborhood Hits	412	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BZI7, Q9H1J0	Gene names	UPF3B, RENT3B, UPF3X
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3B (Nonsense mRNA reducing factor 3B) (Up-frameshift suppressor 3 homolog B) (hUpf3B) (hUpf3p-X).

RABE1_HUMAN
NC score	0.043942 (rank : 93)	θ value	1.81305 (rank : 87)
Query Neighborhood Hits	122	Target Neighborhood Hits	1104	Shared Neighborhood Hits	45
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

TRIM8_HUMAN
NC score	0.041121 (rank : 94)	θ value	0.813845 (rank : 70)
Query Neighborhood Hits	122	Target Neighborhood Hits	650	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

RIMB1_MOUSE
NC score	0.037575 (rank : 95)	θ value	8.99809 (rank : 120)
Query Neighborhood Hits	122	Target Neighborhood Hits	1376	Shared Neighborhood Hits	38
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

MD1L1_MOUSE
NC score	0.037492 (rank : 96)	θ value	2.36792 (rank : 92)
Query Neighborhood Hits	122	Target Neighborhood Hits	1001	Shared Neighborhood Hits	39
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

K0552_HUMAN
NC score	0.037377 (rank : 97)	θ value	8.99809 (rank : 118)
Query Neighborhood Hits	122	Target Neighborhood Hits	442	Shared Neighborhood Hits	29
SwissProt Accessions	O60299	Gene names	KIAA0552
Domain Architecture
Description	Protein KIAA0552.

GOGB1_HUMAN
NC score	0.036820 (rank : 98)	θ value	1.81305 (rank : 83)
Query Neighborhood Hits	122	Target Neighborhood Hits	2297	Shared Neighborhood Hits	65
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

HOOK3_HUMAN
NC score	0.036736 (rank : 99)	θ value	6.88961 (rank : 116)
Query Neighborhood Hits	122	Target Neighborhood Hits	1070	Shared Neighborhood Hits	60
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

JIP3_HUMAN
NC score	0.036612 (rank : 100)	θ value	1.38821 (rank : 76)
Query Neighborhood Hits	122	Target Neighborhood Hits	1039	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

CASC3_MOUSE
NC score	0.032860 (rank : 101)	θ value	1.06291 (rank : 71)
Query Neighborhood Hits	122	Target Neighborhood Hits	333	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

CDT1_HUMAN
NC score	0.032470 (rank : 102)	θ value	3.0926 (rank : 96)
Query Neighborhood Hits	122	Target Neighborhood Hits	92	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H211, Q86XX9, Q96CJ5, Q96GK5, Q96H67, Q96HE6, Q9BWM0	Gene names	CDT1
Domain Architecture	No domain graphic available
Description	DNA replication factor Cdt1 (Double parked homolog) (DUP).

TPR_HUMAN
NC score	0.032439 (rank : 103)	θ value	1.38821 (rank : 78)
Query Neighborhood Hits	122	Target Neighborhood Hits	1921	Shared Neighborhood Hits	54
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

MYH11_MOUSE
NC score	0.031347 (rank : 104)	θ value	0.813845 (rank : 69)
Query Neighborhood Hits	122	Target Neighborhood Hits	1777	Shared Neighborhood Hits	53
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MY18A_MOUSE
NC score	0.030997 (rank : 105)	θ value	4.03905 (rank : 103)
Query Neighborhood Hits	122	Target Neighborhood Hits	1989	Shared Neighborhood Hits	56
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

BAZ1A_HUMAN
NC score	0.030659 (rank : 106)	θ value	4.03905 (rank : 101)
Query Neighborhood Hits	122	Target Neighborhood Hits	693	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

CROCC_MOUSE
NC score	0.030653 (rank : 107)	θ value	6.88961 (rank : 114)
Query Neighborhood Hits	122	Target Neighborhood Hits	1460	Shared Neighborhood Hits	48
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

JIP3_MOUSE
NC score	0.030415 (rank : 108)	θ value	5.27518 (rank : 108)
Query Neighborhood Hits	122	Target Neighborhood Hits	759	Shared Neighborhood Hits	30
SwissProt Accessions	Q9ESN9, Q99KU7, Q9EQD8, Q9ESN7, Q9ESN8, Q9ESP0, Q9JLH2, Q9JLH3, Q9R0U7	Gene names	Mapk8ip3, Jip3, Jsap1, Syd2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3) (JNK/SAPK-associated protein 1) (JSAP1) (Sunday driver 2).

MYH11_HUMAN
NC score	0.029756 (rank : 109)	θ value	1.81305 (rank : 85)
Query Neighborhood Hits	122	Target Neighborhood Hits	1806	Shared Neighborhood Hits	59
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

BSN_HUMAN
NC score	0.029697 (rank : 110)	θ value	6.88961 (rank : 113)
Query Neighborhood Hits	122	Target Neighborhood Hits	1537	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

WBP1_MOUSE
NC score	0.027633 (rank : 111)	θ value	1.38821 (rank : 79)
Query Neighborhood Hits	122	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	P97764, Q8WUP5, Q99J20	Gene names	Wbp1
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 1 (WBP-1).

BEGIN_MOUSE
NC score	0.026249 (rank : 112)	θ value	5.27518 (rank : 105)
Query Neighborhood Hits	122	Target Neighborhood Hits	383	Shared Neighborhood Hits	27
SwissProt Accessions	Q68EF6	Gene names	Begain
Domain Architecture	No domain graphic available
Description	Brain-enriched guanylate kinase-associated protein.

BSN_MOUSE
NC score	0.026229 (rank : 113)	θ value	5.27518 (rank : 106)
Query Neighborhood Hits	122	Target Neighborhood Hits	2057	Shared Neighborhood Hits	43
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

MYH8_MOUSE
NC score	0.025528 (rank : 114)	θ value	1.81305 (rank : 86)
Query Neighborhood Hits	122	Target Neighborhood Hits	1600	Shared Neighborhood Hits	42
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

DPOE1_HUMAN
NC score	0.024611 (rank : 115)	θ value	4.03905 (rank : 102)
Query Neighborhood Hits	122	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q07864, Q13533, Q86VH9	Gene names	POLE, POLE1
Domain Architecture
Description	DNA polymerase epsilon, catalytic subunit A (EC 2.7.7.7) (DNA polymerase II subunit A).

DPOE1_MOUSE
NC score	0.023904 (rank : 116)	θ value	5.27518 (rank : 107)
Query Neighborhood Hits	122	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WVF7, Q9QX50	Gene names	Pole, Pole1
Domain Architecture
Description	DNA polymerase epsilon, catalytic subunit A (EC 2.7.7.7) (DNA polymerase II subunit A).

MYH8_HUMAN
NC score	0.022566 (rank : 117)	θ value	8.99809 (rank : 119)
Query Neighborhood Hits	122	Target Neighborhood Hits	1610	Shared Neighborhood Hits	44
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

DC1L2_MOUSE
NC score	0.022198 (rank : 118)	θ value	1.06291 (rank : 73)
Query Neighborhood Hits	122	Target Neighborhood Hits	173	Shared Neighborhood Hits	6
SwissProt Accessions	Q6PDL0	Gene names	Dync1li2, Dncli2, Dnclic2
Domain Architecture	No domain graphic available
Description	Cytoplasmic dynein 1 light intermediate chain 2 (Dynein light intermediate chain 2, cytosolic).

EYA3_HUMAN
NC score	0.019471 (rank : 119)	θ value	1.81305 (rank : 81)
Query Neighborhood Hits	122	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	Q99504, O95463, Q99813	Gene names	EYA3
Domain Architecture
Description	Eyes absent homolog 3 (EC 3.1.3.48).

RFIP5_MOUSE
NC score	0.019045 (rank : 120)	θ value	2.36792 (rank : 93)
Query Neighborhood Hits	122	Target Neighborhood Hits	126	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R361	Gene names	Rab11fip5, D6Ertd32e, Rip11
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 5 (Rab11-FIP5) (Rab11-interacting protein Rip11).

DAAM2_MOUSE
NC score	0.018980 (rank : 121)	θ value	6.88961 (rank : 115)
Query Neighborhood Hits	122	Target Neighborhood Hits	371	Shared Neighborhood Hits	21
SwissProt Accessions	Q80U19, Q810J5	Gene names	Daam2, Kiaa0381
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 2.

CTRO_MOUSE
NC score	0.018784 (rank : 122)	θ value	0.47712 (rank : 57)
Query Neighborhood Hits	122	Target Neighborhood Hits	2344	Shared Neighborhood Hits	45
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

MRCKB_HUMAN
NC score	0.015239 (rank : 123)	θ value	5.27518 (rank : 109)
Query Neighborhood Hits	122	Target Neighborhood Hits	2239	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

ZN488_HUMAN
NC score	0.014922 (rank : 124)	θ value	2.36792 (rank : 94)
Query Neighborhood Hits	122	Target Neighborhood Hits	484	Shared Neighborhood Hits	3
SwissProt Accessions	Q96MN9	Gene names	ZNF488
Domain Architecture	No domain graphic available
Description	Zinc finger protein 488.

RTN1_MOUSE
NC score	0.013924 (rank : 125)	θ value	5.27518 (rank : 110)
Query Neighborhood Hits	122	Target Neighborhood Hits	189	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K0T0, Q8K4S4	Gene names	Rtn1, Nsp
Domain Architecture	No domain graphic available
Description	Reticulon-1 (Neuroendocrine-specific protein).

TSNA1_HUMAN
NC score	0.013025 (rank : 126)	θ value	8.99809 (rank : 122)
Query Neighborhood Hits	122	Target Neighborhood Hits	178	Shared Neighborhood Hits	10
SwissProt Accessions	Q96NA8	Gene names	TSNARE1
Domain Architecture	No domain graphic available
Description	t-SNARE domain-containing protein 1.

MUC1_HUMAN
NC score	0.011984 (rank : 127)	θ value	0.21417 (rank : 50)
Query Neighborhood Hits	122	Target Neighborhood Hits	975	Shared Neighborhood Hits	12
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

RGS3_HUMAN
NC score	0.011750 (rank : 128)	θ value	3.0926 (rank : 100)
Query Neighborhood Hits	122	Target Neighborhood Hits	1375	Shared Neighborhood Hits	16
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

TSH1_HUMAN
NC score	0.011141 (rank : 129)	θ value	1.81305 (rank : 89)
Query Neighborhood Hits	122	Target Neighborhood Hits	558	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZSZ6, O60534, Q4LE29, Q53EU4	Gene names	TSHZ1, SDCCAG33, TSH1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3) (Antigen NY-CO-33).

OGFR_HUMAN
NC score	0.009132 (rank : 130)	θ value	4.03905 (rank : 104)
Query Neighborhood Hits	122	Target Neighborhood Hits	1582	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

TCGAP_HUMAN
NC score	0.008724 (rank : 131)	θ value	8.99809 (rank : 121)
Query Neighborhood Hits	122	Target Neighborhood Hits	872	Shared Neighborhood Hits	14
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

FOXK2_HUMAN
NC score	0.008184 (rank : 132)	θ value	1.81305 (rank : 82)
Query Neighborhood Hits	122	Target Neighborhood Hits	190	Shared Neighborhood Hits	3
SwissProt Accessions	Q01167, Q13622, Q13623, Q13624	Gene names	FOXK2, ILF, ILF1
Domain Architecture
Description	Forkhead box protein K2 (Interleukin enhancer-binding factor 1) (Cellular transcription factor ILF-1).

BARH1_HUMAN
NC score	0.003232 (rank : 133)	θ value	2.36792 (rank : 90)
Query Neighborhood Hits	122	Target Neighborhood Hits	373	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BZE3, Q9NY88	Gene names	BARHL1
Domain Architecture
Description	BarH-like 1 homeobox protein.

ZN687_HUMAN
NC score	0.002556 (rank : 134)	θ value	2.36792 (rank : 95)
Query Neighborhood Hits	122	Target Neighborhood Hits	1244	Shared Neighborhood Hits	14
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

CUBN_HUMAN
NC score	-0.000685 (rank : 135)	θ value	8.99809 (rank : 117)
Query Neighborhood Hits	122	Target Neighborhood Hits	482	Shared Neighborhood Hits	2
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).