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Network neighborhood for query Sequence : ATF6B_HUMAN

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ATF6B_HUMAN
SwissProt Accessions	Q99941, Q13269, Q14343, Q14345, Q99635, Q99637, Q9H3V9, Q9H3W1, Q9NPL0	Gene names	CREBL1, G13
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp) (Protein G13).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ATF6B_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	122	Target Neighborhood Hits	122	Shared Neighborhood Hits	122
SwissProt Accessions	Q99941, Q13269, Q14343, Q14345, Q99635, Q99637, Q9H3V9, Q9H3W1, Q9NPL0	Gene names	CREBL1, G13
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp) (Protein G13).

ATF6B_MOUSE
θ value	0 (rank : 2)	NC score	0.969067 (rank : 2)
Query Neighborhood Hits	122	Target Neighborhood Hits	97	Shared Neighborhood Hits	44
SwissProt Accessions	O35451	Gene names	Crebl1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp).

ATF6A_HUMAN
θ value	6.96618e-77 (rank : 3)	NC score	0.848346 (rank : 3)
Query Neighborhood Hits	122	Target Neighborhood Hits	174	Shared Neighborhood Hits	37
SwissProt Accessions	P18850, O15139, Q5VW62, Q6IPB5, Q9UEC9	Gene names	ATF6
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 alpha (Activating transcription factor 6 alpha) (ATF6-alpha).

CREB3_HUMAN
θ value	1.09739e-05 (rank : 4)	NC score	0.360808 (rank : 5)
Query Neighborhood Hits	122	Target Neighborhood Hits	138	Shared Neighborhood Hits	27
SwissProt Accessions	O43889, O14671, O14919, Q96GK8, Q9H2W3, Q9UE77	Gene names	CREB3, LZIP
Domain Architecture	No domain graphic available
Description	Cyclic AMP-responsive element-binding protein 3 (Luman protein) (Transcription factor LZIP-alpha).

CREB3_MOUSE
θ value	1.87187e-05 (rank : 5)	NC score	0.367717 (rank : 4)
Query Neighborhood Hits	122	Target Neighborhood Hits	97	Shared Neighborhood Hits	25
SwissProt Accessions	Q61817, Q99M21, Q9CVK9	Gene names	Creb3, Lzip
Domain Architecture	No domain graphic available
Description	Cyclic AMP-responsive element-binding protein 3 (Transcription factor LZIP).

CREM_HUMAN
θ value	4.1701e-05 (rank : 6)	NC score	0.335952 (rank : 8)
Query Neighborhood Hits	122	Target Neighborhood Hits	63	Shared Neighborhood Hits	19
SwissProt Accessions	Q03060, Q16114, Q16116, Q9NZB9	Gene names	CREM
Domain Architecture
Description	cAMP-responsive element modulator.

CREM_MOUSE
θ value	5.44631e-05 (rank : 7)	NC score	0.333431 (rank : 9)
Query Neighborhood Hits	122	Target Neighborhood Hits	58	Shared Neighborhood Hits	19
SwissProt Accessions	P27699, P27698	Gene names	Crem
Domain Architecture
Description	cAMP-responsive element modulator.

ATF1_HUMAN
θ value	9.29e-05 (rank : 8)	NC score	0.349946 (rank : 6)
Query Neighborhood Hits	122	Target Neighborhood Hits	59	Shared Neighborhood Hits	21
SwissProt Accessions	P18846, P25168	Gene names	ATF1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-1 (Activating transcription factor 1) (TREB36 protein).

ATF1_MOUSE
θ value	0.00035302 (rank : 9)	NC score	0.343333 (rank : 7)
Query Neighborhood Hits	122	Target Neighborhood Hits	70	Shared Neighborhood Hits	21
SwissProt Accessions	P81269	Gene names	Atf1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-1 (Activating transcription factor 1) (TCR-ATF1).

ZHANG_HUMAN
θ value	0.00134147 (rank : 10)	NC score	0.301277 (rank : 13)
Query Neighborhood Hits	122	Target Neighborhood Hits	24	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NS37	Gene names	ZF
Domain Architecture	No domain graphic available
Description	Host cell factor-binding transcription factor Zhangfei (HCF-binding transcription factor Zhangfei).

ZHANG_MOUSE
θ value	0.00134147 (rank : 11)	NC score	0.301379 (rank : 12)
Query Neighborhood Hits	122	Target Neighborhood Hits	20	Shared Neighborhood Hits	8
SwissProt Accessions	Q91ZR3, Q91Y72	Gene names	Zf
Domain Architecture	No domain graphic available
Description	Host cell factor-binding transcription factor Zhangfei (HCF-binding transcription factor Zhangfei) (Tyrosine kinase-associated leucine zipper protein LAZip).

MEGF9_HUMAN
θ value	0.00175202 (rank : 12)	NC score	0.039584 (rank : 51)
Query Neighborhood Hits	122	Target Neighborhood Hits	557	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

CREB1_HUMAN
θ value	0.00228821 (rank : 13)	NC score	0.310746 (rank : 11)
Query Neighborhood Hits	122	Target Neighborhood Hits	57	Shared Neighborhood Hits	20
SwissProt Accessions	P16220, P21934, Q9UMA7	Gene names	CREB1
Domain Architecture
Description	cAMP response element-binding protein (CREB).

CREB1_MOUSE
θ value	0.00228821 (rank : 14)	NC score	0.310759 (rank : 10)
Query Neighborhood Hits	122	Target Neighborhood Hits	58	Shared Neighborhood Hits	20
SwissProt Accessions	Q01147	Gene names	Creb1, Creb-1
Domain Architecture
Description	cAMP response element-binding protein (CREB).

ATF7_HUMAN
θ value	0.0252991 (rank : 15)	NC score	0.181528 (rank : 14)
Query Neighborhood Hits	122	Target Neighborhood Hits	333	Shared Neighborhood Hits	30
SwissProt Accessions	P17544, Q13814	Gene names	ATF7, ATFA
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

ATF7_MOUSE
θ value	0.0252991 (rank : 16)	NC score	0.181357 (rank : 15)
Query Neighborhood Hits	122	Target Neighborhood Hits	286	Shared Neighborhood Hits	28
SwissProt Accessions	Q8R0S1	Gene names	Atf7
Domain Architecture	No domain graphic available
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

CDC37_HUMAN
θ value	0.0563607 (rank : 17)	NC score	0.086394 (rank : 27)
Query Neighborhood Hits	122	Target Neighborhood Hits	506	Shared Neighborhood Hits	12
SwissProt Accessions	Q16543	Gene names	CDC37
Domain Architecture
Description	Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37).

XBP1_MOUSE
θ value	0.0563607 (rank : 18)	NC score	0.173235 (rank : 16)
Query Neighborhood Hits	122	Target Neighborhood Hits	99	Shared Neighborhood Hits	13
SwissProt Accessions	O35426, Q8VHM0, Q922G5, Q9ESS3	Gene names	Xbp1, Treb5
Domain Architecture	No domain graphic available
Description	X box-binding protein 1 (XBP-1) (Tax-responsive element-binding protein 5 homolog).

PCQAP_HUMAN
θ value	0.0736092 (rank : 19)	NC score	0.083383 (rank : 30)
Query Neighborhood Hits	122	Target Neighborhood Hits	549	Shared Neighborhood Hits	28
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

DIAP1_MOUSE
θ value	0.0961366 (rank : 20)	NC score	0.035837 (rank : 59)
Query Neighborhood Hits	122	Target Neighborhood Hits	839	Shared Neighborhood Hits	27
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

RIMB1_MOUSE
θ value	0.0961366 (rank : 21)	NC score	0.052110 (rank : 37)
Query Neighborhood Hits	122	Target Neighborhood Hits	1376	Shared Neighborhood Hits	36
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

ATF5_MOUSE
θ value	0.125558 (rank : 22)	NC score	0.079382 (rank : 31)
Query Neighborhood Hits	122	Target Neighborhood Hits	62	Shared Neighborhood Hits	11
SwissProt Accessions	O70191, Q58E51, Q99NH6	Gene names	Atf5, Atfx, Nap1
Domain Architecture	No domain graphic available
Description	Cyclic AMP-dependent transcription factor ATF-5 (Activating transcription factor 5-alpha/beta) (Transcription factor ATFx) (Transcription factor-like protein ODA-10) (BZIP protein ATF7) (NRIF3- associated protein) (NAP1).

ATF2_HUMAN
θ value	0.21417 (rank : 23)	NC score	0.153451 (rank : 17)
Query Neighborhood Hits	122	Target Neighborhood Hits	402	Shared Neighborhood Hits	32
SwissProt Accessions	P15336, Q13000	Gene names	ATF2, CREB2, CREBP1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (HB16).

ATF2_MOUSE
θ value	0.21417 (rank : 24)	NC score	0.151952 (rank : 18)
Query Neighborhood Hits	122	Target Neighborhood Hits	397	Shared Neighborhood Hits	32
SwissProt Accessions	P16951, Q64089, Q64090, Q64091	Gene names	Atf2
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (MXBP protein).

BAZ2A_MOUSE
θ value	0.279714 (rank : 25)	NC score	0.051765 (rank : 38)
Query Neighborhood Hits	122	Target Neighborhood Hits	744	Shared Neighborhood Hits	41
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

K1543_MOUSE
θ value	0.279714 (rank : 26)	NC score	0.061296 (rank : 33)
Query Neighborhood Hits	122	Target Neighborhood Hits	497	Shared Neighborhood Hits	29
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

MAP4_MOUSE
θ value	0.279714 (rank : 27)	NC score	0.048231 (rank : 40)
Query Neighborhood Hits	122	Target Neighborhood Hits	409	Shared Neighborhood Hits	19
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MUC1_HUMAN
θ value	0.279714 (rank : 28)	NC score	0.044832 (rank : 42)
Query Neighborhood Hits	122	Target Neighborhood Hits	975	Shared Neighborhood Hits	44
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

JUNB_HUMAN
θ value	0.365318 (rank : 29)	NC score	0.131924 (rank : 20)
Query Neighborhood Hits	122	Target Neighborhood Hits	97	Shared Neighborhood Hits	24
SwissProt Accessions	P17275, Q96GH3	Gene names	JUNB
Domain Architecture
Description	Transcription factor jun-B.

JUNB_MOUSE
θ value	0.365318 (rank : 30)	NC score	0.129316 (rank : 21)
Query Neighborhood Hits	122	Target Neighborhood Hits	116	Shared Neighborhood Hits	24
SwissProt Accessions	P09450, Q8C2G9	Gene names	Junb, Jun-b
Domain Architecture
Description	Transcription factor jun-B.

PCQAP_MOUSE
θ value	0.365318 (rank : 31)	NC score	0.068033 (rank : 32)
Query Neighborhood Hits	122	Target Neighborhood Hits	506	Shared Neighborhood Hits	24
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

PARD3_MOUSE
θ value	0.62314 (rank : 32)	NC score	0.021290 (rank : 88)
Query Neighborhood Hits	122	Target Neighborhood Hits	290	Shared Neighborhood Hits	7
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

BAT2_HUMAN
θ value	0.813845 (rank : 33)	NC score	0.056401 (rank : 34)
Query Neighborhood Hits	122	Target Neighborhood Hits	931	Shared Neighborhood Hits	44
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CDX2_MOUSE
θ value	0.813845 (rank : 34)	NC score	0.019163 (rank : 93)
Query Neighborhood Hits	122	Target Neighborhood Hits	336	Shared Neighborhood Hits	9
SwissProt Accessions	P43241	Gene names	Cdx2, Cdx-2
Domain Architecture
Description	Homeobox protein CDX-2 (Caudal-type homeobox protein 2).

NDE1_HUMAN
θ value	0.813845 (rank : 35)	NC score	0.029665 (rank : 69)
Query Neighborhood Hits	122	Target Neighborhood Hits	823	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NXR1, Q49AQ2	Gene names	NDE1, NUDE
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE).

RFIP3_HUMAN
θ value	0.813845 (rank : 36)	NC score	0.040584 (rank : 48)
Query Neighborhood Hits	122	Target Neighborhood Hits	1055	Shared Neighborhood Hits	34
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

SPAG5_HUMAN
θ value	0.813845 (rank : 37)	NC score	0.033377 (rank : 63)
Query Neighborhood Hits	122	Target Neighborhood Hits	625	Shared Neighborhood Hits	19
SwissProt Accessions	Q96R06, O95213, Q9BWE8, Q9NT17, Q9UFE6	Gene names	SPAG5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Astrin) (Mitotic spindle-associated protein p126) (MAP126) (Deepest).

MDC1_MOUSE
θ value	1.06291 (rank : 38)	NC score	0.054582 (rank : 35)
Query Neighborhood Hits	122	Target Neighborhood Hits	998	Shared Neighborhood Hits	47
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MELPH_HUMAN
θ value	1.06291 (rank : 39)	NC score	0.047710 (rank : 41)
Query Neighborhood Hits	122	Target Neighborhood Hits	145	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BV36, Q9HA71	Gene names	MLPH, SLAC2A
Domain Architecture	No domain graphic available
Description	Melanophilin (Exophilin-3) (Synaptotagmin-like protein 2a) (Slp homolog lacking C2 domains a).

TITIN_HUMAN
θ value	1.06291 (rank : 40)	NC score	0.008257 (rank : 123)
Query Neighborhood Hits	122	Target Neighborhood Hits	2923	Shared Neighborhood Hits	49
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

UROL1_HUMAN
θ value	1.06291 (rank : 41)	NC score	0.026356 (rank : 77)
Query Neighborhood Hits	122	Target Neighborhood Hits	213	Shared Neighborhood Hits	3
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

CDX2_HUMAN
θ value	1.38821 (rank : 42)	NC score	0.017422 (rank : 95)
Query Neighborhood Hits	122	Target Neighborhood Hits	330	Shared Neighborhood Hits	7
SwissProt Accessions	Q99626, O00503, Q969L8	Gene names	CDX2, CDX3
Domain Architecture
Description	Homeobox protein CDX-2 (Caudal-type homeobox protein 2) (CDX-3).

RIMB1_HUMAN
θ value	1.38821 (rank : 43)	NC score	0.043550 (rank : 46)
Query Neighborhood Hits	122	Target Neighborhood Hits	1479	Shared Neighborhood Hits	43
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

HEBP2_MOUSE
θ value	1.81305 (rank : 44)	NC score	0.034537 (rank : 61)
Query Neighborhood Hits	122	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WU63	Gene names	Hebp2, Soul
Domain Architecture	No domain graphic available
Description	Heme-binding protein 2 (Protein SOUL).

HOOK1_MOUSE
θ value	1.81305 (rank : 45)	NC score	0.026368 (rank : 76)
Query Neighborhood Hits	122	Target Neighborhood Hits	910	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BIL5, Q8BIZ2, Q8K0P1, Q8K454, Q9CTN6	Gene names	Hook1
Domain Architecture
Description	Hook homolog 1.

MK07_HUMAN
θ value	1.81305 (rank : 46)	NC score	0.005267 (rank : 126)
Query Neighborhood Hits	122	Target Neighborhood Hits	1087	Shared Neighborhood Hits	21
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

MYCB2_HUMAN
θ value	1.81305 (rank : 47)	NC score	0.020038 (rank : 92)
Query Neighborhood Hits	122	Target Neighborhood Hits	390	Shared Neighborhood Hits	5
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

P3C2B_HUMAN
θ value	1.81305 (rank : 48)	NC score	0.013031 (rank : 108)
Query Neighborhood Hits	122	Target Neighborhood Hits	148	Shared Neighborhood Hits	5
SwissProt Accessions	O00750, O95666, Q5SW99	Gene names	PIK3C2B
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-beta) (PtdIns-3-kinase C2 beta) (PI3K-C2beta) (C2-PI3K).

PRA12_HUMAN
θ value	1.81305 (rank : 49)	NC score	0.014941 (rank : 101)
Query Neighborhood Hits	122	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	O95522	Gene names
Domain Architecture	No domain graphic available
Description	PRAME family member DJ1198H6.2.

RTP3_MOUSE
θ value	1.81305 (rank : 50)	NC score	0.034566 (rank : 60)
Query Neighborhood Hits	122	Target Neighborhood Hits	374	Shared Neighborhood Hits	23
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

TBC10_HUMAN
θ value	1.81305 (rank : 51)	NC score	0.020748 (rank : 90)
Query Neighborhood Hits	122	Target Neighborhood Hits	64	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BXI6, O76053, Q543A2	Gene names	TBC1D10A, EPI64, TBC1D10
Domain Architecture
Description	TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa) (EPI64 protein).

WASP_HUMAN
θ value	1.81305 (rank : 52)	NC score	0.029973 (rank : 67)
Query Neighborhood Hits	122	Target Neighborhood Hits	195	Shared Neighborhood Hits	17
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

CD2L7_HUMAN
θ value	2.36792 (rank : 53)	NC score	0.004922 (rank : 128)
Query Neighborhood Hits	122	Target Neighborhood Hits	1275	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

CREB5_HUMAN
θ value	2.36792 (rank : 54)	NC score	0.150139 (rank : 19)
Query Neighborhood Hits	122	Target Neighborhood Hits	222	Shared Neighborhood Hits	25
SwissProt Accessions	Q02930, Q05886, Q06246	Gene names	CREB5, CREBPA
Domain Architecture
Description	cAMP response element-binding protein 5 (CRE-BPa).

CSKI1_HUMAN
θ value	2.36792 (rank : 55)	NC score	0.016138 (rank : 100)
Query Neighborhood Hits	122	Target Neighborhood Hits	997	Shared Neighborhood Hits	36
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

LR37B_HUMAN
θ value	2.36792 (rank : 56)	NC score	0.020857 (rank : 89)
Query Neighborhood Hits	122	Target Neighborhood Hits	392	Shared Neighborhood Hits	13
SwissProt Accessions	Q96QE4, Q5YKG6	Gene names	LRRC37B
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37B precursor (C66 SLIT-like testicular protein).

MADCA_HUMAN
θ value	2.36792 (rank : 57)	NC score	0.038935 (rank : 54)
Query Neighborhood Hits	122	Target Neighborhood Hits	221	Shared Neighborhood Hits	17
SwissProt Accessions	Q13477, O60222, O75867	Gene names	MADCAM1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (hMAdCAM-1).

NCOR1_HUMAN
θ value	2.36792 (rank : 58)	NC score	0.026079 (rank : 78)
Query Neighborhood Hits	122	Target Neighborhood Hits	577	Shared Neighborhood Hits	21
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

WBP11_HUMAN
θ value	2.36792 (rank : 59)	NC score	0.044575 (rank : 44)
Query Neighborhood Hits	122	Target Neighborhood Hits	354	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

WBP11_MOUSE
θ value	2.36792 (rank : 60)	NC score	0.044658 (rank : 43)
Query Neighborhood Hits	122	Target Neighborhood Hits	362	Shared Neighborhood Hits	18
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

BAT3_MOUSE
θ value	3.0926 (rank : 61)	NC score	0.038679 (rank : 56)
Query Neighborhood Hits	122	Target Neighborhood Hits	518	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

ELK1_HUMAN
θ value	3.0926 (rank : 62)	NC score	0.012601 (rank : 109)
Query Neighborhood Hits	122	Target Neighborhood Hits	112	Shared Neighborhood Hits	6
SwissProt Accessions	P19419, O75606, O95058, Q969X8, Q9UJM4	Gene names	ELK1
Domain Architecture
Description	ETS domain-containing protein Elk-1.

MAD4_MOUSE
θ value	3.0926 (rank : 63)	NC score	0.039827 (rank : 50)
Query Neighborhood Hits	122	Target Neighborhood Hits	65	Shared Neighborhood Hits	7
SwissProt Accessions	Q60948	Gene names	Mxd4, Mad4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

MLL3_MOUSE
θ value	3.0926 (rank : 64)	NC score	0.029389 (rank : 71)
Query Neighborhood Hits	122	Target Neighborhood Hits	1399	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

RTN4_HUMAN
θ value	3.0926 (rank : 65)	NC score	0.023875 (rank : 83)
Query Neighborhood Hits	122	Target Neighborhood Hits	357	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

SEPT9_HUMAN
θ value	3.0926 (rank : 66)	NC score	0.025810 (rank : 79)
Query Neighborhood Hits	122	Target Neighborhood Hits	706	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

SON_HUMAN
θ value	3.0926 (rank : 67)	NC score	0.038717 (rank : 55)
Query Neighborhood Hits	122	Target Neighborhood Hits	1568	Shared Neighborhood Hits	63
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

ALEX_MOUSE
θ value	4.03905 (rank : 68)	NC score	0.030914 (rank : 66)
Query Neighborhood Hits	122	Target Neighborhood Hits	197	Shared Neighborhood Hits	15
SwissProt Accessions	Q6R0H6, Q8BIR3	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

BAT2_MOUSE
θ value	4.03905 (rank : 69)	NC score	0.043584 (rank : 45)
Query Neighborhood Hits	122	Target Neighborhood Hits	947	Shared Neighborhood Hits	45
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

DDEF2_HUMAN
θ value	4.03905 (rank : 70)	NC score	0.014250 (rank : 105)
Query Neighborhood Hits	122	Target Neighborhood Hits	599	Shared Neighborhood Hits	22
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

KCNN3_HUMAN
θ value	4.03905 (rank : 71)	NC score	0.014410 (rank : 104)
Query Neighborhood Hits	122	Target Neighborhood Hits	216	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UGI6, O43517	Gene names	KCNN3, K3
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 3 (SK3) (SKCa3).

PODXL_HUMAN
θ value	4.03905 (rank : 72)	NC score	0.033556 (rank : 62)
Query Neighborhood Hits	122	Target Neighborhood Hits	191	Shared Neighborhood Hits	12
SwissProt Accessions	O00592	Gene names	PODXL, PCLP, PCLP1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

RAVR2_HUMAN
θ value	4.03905 (rank : 73)	NC score	0.014527 (rank : 103)
Query Neighborhood Hits	122	Target Neighborhood Hits	144	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HCJ3, Q6P141, Q9NPV7	Gene names	RAVER2, KIAA1579
Domain Architecture	No domain graphic available
Description	Ribonucleoprotein PTB-binding 2 (Protein raver-2).

RC3H1_HUMAN
θ value	4.03905 (rank : 74)	NC score	0.020121 (rank : 91)
Query Neighborhood Hits	122	Target Neighborhood Hits	433	Shared Neighborhood Hits	22
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

SATB2_HUMAN
θ value	4.03905 (rank : 75)	NC score	0.030981 (rank : 64)
Query Neighborhood Hits	122	Target Neighborhood Hits	58	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UPW6	Gene names	SATB2, KIAA1034
Domain Architecture
Description	DNA-binding protein SATB2 (Special AT-rich sequence-binding protein 2).

SATB2_MOUSE
θ value	4.03905 (rank : 76)	NC score	0.030978 (rank : 65)
Query Neighborhood Hits	122	Target Neighborhood Hits	58	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VI24	Gene names	Satb2, Kiaa1034
Domain Architecture
Description	DNA-binding protein SATB2 (Special AT-rich sequence-binding protein 2).

WASIP_MOUSE
θ value	4.03905 (rank : 77)	NC score	0.037435 (rank : 58)
Query Neighborhood Hits	122	Target Neighborhood Hits	392	Shared Neighborhood Hits	25
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

AB1IP_MOUSE
θ value	5.27518 (rank : 78)	NC score	0.017116 (rank : 96)
Query Neighborhood Hits	122	Target Neighborhood Hits	181	Shared Neighborhood Hits	12
SwissProt Accessions	Q8R5A3, O35329, Q8BRU0, Q99KV8	Gene names	Apbb1ip, Prel1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 48).

ATBF1_HUMAN
θ value	5.27518 (rank : 79)	NC score	0.008977 (rank : 120)
Query Neighborhood Hits	122	Target Neighborhood Hits	1547	Shared Neighborhood Hits	32
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

CDX1_MOUSE
θ value	5.27518 (rank : 80)	NC score	0.013543 (rank : 107)
Query Neighborhood Hits	122	Target Neighborhood Hits	379	Shared Neighborhood Hits	14
SwissProt Accessions	P18111, Q8VCF7	Gene names	Cdx1, Cdx-1
Domain Architecture
Description	Homeobox protein CDX-1 (Caudal-type homeobox protein 1).

CI039_HUMAN
θ value	5.27518 (rank : 81)	NC score	0.018089 (rank : 94)
Query Neighborhood Hits	122	Target Neighborhood Hits	1171	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

FMN2_HUMAN
θ value	5.27518 (rank : 82)	NC score	0.028704 (rank : 72)
Query Neighborhood Hits	122	Target Neighborhood Hits	484	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

HMMR_MOUSE
θ value	5.27518 (rank : 83)	NC score	0.013632 (rank : 106)
Query Neighborhood Hits	122	Target Neighborhood Hits	1178	Shared Neighborhood Hits	24
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

HOOK1_HUMAN
θ value	5.27518 (rank : 84)	NC score	0.022081 (rank : 86)
Query Neighborhood Hits	122	Target Neighborhood Hits	942	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

MAP1A_HUMAN
θ value	5.27518 (rank : 85)	NC score	0.023919 (rank : 82)
Query Neighborhood Hits	122	Target Neighborhood Hits	1626	Shared Neighborhood Hits	52
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MRCKB_MOUSE
θ value	5.27518 (rank : 86)	NC score	0.009977 (rank : 118)
Query Neighborhood Hits	122	Target Neighborhood Hits	2180	Shared Neighborhood Hits	38
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

SATB1_HUMAN
θ value	5.27518 (rank : 87)	NC score	0.029830 (rank : 68)
Query Neighborhood Hits	122	Target Neighborhood Hits	130	Shared Neighborhood Hits	10
SwissProt Accessions	Q01826	Gene names	SATB1
Domain Architecture
Description	DNA-binding protein SATB1 (Special AT-rich sequence-binding protein 1).

TUFT1_MOUSE
θ value	5.27518 (rank : 88)	NC score	0.016542 (rank : 98)
Query Neighborhood Hits	122	Target Neighborhood Hits	732	Shared Neighborhood Hits	23
SwissProt Accessions	O08970	Gene names	Tuft1
Domain Architecture
Description	Tuftelin.

UBP49_HUMAN
θ value	5.27518 (rank : 89)	NC score	0.011607 (rank : 112)
Query Neighborhood Hits	122	Target Neighborhood Hits	100	Shared Neighborhood Hits	3
SwissProt Accessions	Q70CQ1, Q96CK4	Gene names	USP49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

ZN282_HUMAN
θ value	5.27518 (rank : 90)	NC score	-0.001286 (rank : 130)
Query Neighborhood Hits	122	Target Neighborhood Hits	796	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UDV7, O43691, Q6DKK0	Gene names	ZNF282, HUB1
Domain Architecture
Description	Zinc finger protein 282 (HTLV-I U5RE-binding protein 1) (HUB-1).

BATF_MOUSE
θ value	6.88961 (rank : 91)	NC score	0.052646 (rank : 36)
Query Neighborhood Hits	122	Target Neighborhood Hits	100	Shared Neighborhood Hits	13
SwissProt Accessions	O35284	Gene names	Batf
Domain Architecture
Description	ATF-like basic leucine zipper transcription factor B-ATF.

GON4L_HUMAN
θ value	6.88961 (rank : 92)	NC score	0.016929 (rank : 97)
Query Neighborhood Hits	122	Target Neighborhood Hits	555	Shared Neighborhood Hits	23
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

HCLS1_HUMAN
θ value	6.88961 (rank : 93)	NC score	0.011812 (rank : 110)
Query Neighborhood Hits	122	Target Neighborhood Hits	358	Shared Neighborhood Hits	17
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

HXA10_MOUSE
θ value	6.88961 (rank : 94)	NC score	0.008313 (rank : 122)
Query Neighborhood Hits	122	Target Neighborhood Hits	365	Shared Neighborhood Hits	11
SwissProt Accessions	P31310, Q80Y22	Gene names	Hoxa10, Hox-1.8, Hoxa-10
Domain Architecture
Description	Homeobox protein Hox-A10 (Hox-1.8).

PCLO_HUMAN
θ value	6.88961 (rank : 95)	NC score	0.027509 (rank : 75)
Query Neighborhood Hits	122	Target Neighborhood Hits	2046	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

SET1A_HUMAN
θ value	6.88961 (rank : 96)	NC score	0.024618 (rank : 81)
Query Neighborhood Hits	122	Target Neighborhood Hits	690	Shared Neighborhood Hits	27
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SHAN1_HUMAN
θ value	6.88961 (rank : 97)	NC score	0.014883 (rank : 102)
Query Neighborhood Hits	122	Target Neighborhood Hits	1041	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SYNE2_HUMAN
θ value	6.88961 (rank : 98)	NC score	0.011280 (rank : 113)
Query Neighborhood Hits	122	Target Neighborhood Hits	1323	Shared Neighborhood Hits	28
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

TOP2A_HUMAN
θ value	6.88961 (rank : 99)	NC score	0.010989 (rank : 115)
Query Neighborhood Hits	122	Target Neighborhood Hits	135	Shared Neighborhood Hits	5
SwissProt Accessions	P11388, Q71UN1, Q9HB24, Q9HB25, Q9HB26, Q9UP44, Q9UQP9	Gene names	TOP2A, TOP2
Domain Architecture
Description	DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme).

TP53B_MOUSE
θ value	6.88961 (rank : 100)	NC score	0.023235 (rank : 84)
Query Neighborhood Hits	122	Target Neighborhood Hits	644	Shared Neighborhood Hits	26
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TREF1_HUMAN
θ value	6.88961 (rank : 101)	NC score	0.010882 (rank : 116)
Query Neighborhood Hits	122	Target Neighborhood Hits	651	Shared Neighborhood Hits	13
SwissProt Accessions	Q96PN7, Q7Z6T2, Q7Z6T3, Q9NQ72, Q9NQ73, Q9NUN9	Gene names	TRERF1, RAPA, TREP132
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132) (Zinc finger protein rapa).

FMNL_HUMAN
θ value	8.99809 (rank : 102)	NC score	0.027542 (rank : 74)
Query Neighborhood Hits	122	Target Neighborhood Hits	529	Shared Neighborhood Hits	30
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

FOG1_MOUSE
θ value	8.99809 (rank : 103)	NC score	0.004953 (rank : 127)
Query Neighborhood Hits	122	Target Neighborhood Hits	1237	Shared Neighborhood Hits	30
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

GAK8_HUMAN
θ value	8.99809 (rank : 104)	NC score	0.006123 (rank : 125)
Query Neighborhood Hits	122	Target Neighborhood Hits	145	Shared Neighborhood Hits	13
SwissProt Accessions	Q9HDB9	Gene names	ERVK5
Domain Architecture	No domain graphic available
Description	HERV-K_3q12.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(II) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GGA1_HUMAN
θ value	8.99809 (rank : 105)	NC score	0.011000 (rank : 114)
Query Neighborhood Hits	122	Target Neighborhood Hits	169	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UJY5, Q5TG07, Q9BW94, Q9UG00, Q9UGW0, Q9UGW1	Gene names	GGA1
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

GGN_HUMAN
θ value	8.99809 (rank : 106)	NC score	0.029661 (rank : 70)
Query Neighborhood Hits	122	Target Neighborhood Hits	269	Shared Neighborhood Hits	15
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

HD_HUMAN
θ value	8.99809 (rank : 107)	NC score	0.011807 (rank : 111)
Query Neighborhood Hits	122	Target Neighborhood Hits	165	Shared Neighborhood Hits	6
SwissProt Accessions	P42858, Q9UQB7	Gene names	HD, IT15
Domain Architecture
Description	Huntingtin (Huntington disease protein) (HD protein).

HLX1_HUMAN
θ value	8.99809 (rank : 108)	NC score	0.007809 (rank : 124)
Query Neighborhood Hits	122	Target Neighborhood Hits	370	Shared Neighborhood Hits	8
SwissProt Accessions	Q14774, Q15988	Gene names	HLX1
Domain Architecture
Description	Homeobox protein HLX1 (Homeobox protein HB24).

LAMA2_MOUSE
θ value	8.99809 (rank : 109)	NC score	0.009240 (rank : 119)
Query Neighborhood Hits	122	Target Neighborhood Hits	1198	Shared Neighborhood Hits	17
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

MAD4_HUMAN
θ value	8.99809 (rank : 110)	NC score	0.025147 (rank : 80)
Query Neighborhood Hits	122	Target Neighborhood Hits	94	Shared Neighborhood Hits	8
SwissProt Accessions	Q14582, Q5TZX4	Gene names	MXD4, MAD4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

MAFB_HUMAN
θ value	8.99809 (rank : 111)	NC score	0.039468 (rank : 52)
Query Neighborhood Hits	122	Target Neighborhood Hits	96	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y5Q3, Q9H1F1	Gene names	MAFB, KRML
Domain Architecture
Description	Transcription factor MafB (V-maf musculoaponeurotic fibrosarcoma oncogene homolog B).

MAFB_MOUSE
θ value	8.99809 (rank : 112)	NC score	0.040873 (rank : 47)
Query Neighborhood Hits	122	Target Neighborhood Hits	92	Shared Neighborhood Hits	16
SwissProt Accessions	P54841	Gene names	Mafb, Krml, Maf1
Domain Architecture
Description	Transcription factor MafB (V-maf musculoaponeurotic fibrosarcoma oncogene homolog B) (Transcription factor MAF1) (Segmentation protein KR) (Kreisler).

MAFF_HUMAN
θ value	8.99809 (rank : 113)	NC score	0.039279 (rank : 53)
Query Neighborhood Hits	122	Target Neighborhood Hits	54	Shared Neighborhood Hits	13
SwissProt Accessions	Q9ULX9, Q9Y525	Gene names	MAFF
Domain Architecture
Description	Transcription factor MafF (V-maf musculoaponeurotic fibrosarcoma oncogene homolog F) (U-Maf).

MAFF_MOUSE
θ value	8.99809 (rank : 114)	NC score	0.040252 (rank : 49)
Query Neighborhood Hits	122	Target Neighborhood Hits	53	Shared Neighborhood Hits	13
SwissProt Accessions	O54791	Gene names	Maff
Domain Architecture
Description	Transcription factor MafF (V-maf musculoaponeurotic fibrosarcoma oncogene homolog F).

MEF2A_HUMAN
θ value	8.99809 (rank : 115)	NC score	0.008326 (rank : 121)
Query Neighborhood Hits	122	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	Q02078, O43814, Q14223, Q14224, Q96D14	Gene names	MEF2A, MEF2
Domain Architecture
Description	Myocyte-specific enhancer factor 2A (Serum response factor-like protein 1).

MLL3_HUMAN
θ value	8.99809 (rank : 116)	NC score	0.037589 (rank : 57)
Query Neighborhood Hits	122	Target Neighborhood Hits	1644	Shared Neighborhood Hits	67
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

PRR8_HUMAN
θ value	8.99809 (rank : 117)	NC score	0.027684 (rank : 73)
Query Neighborhood Hits	122	Target Neighborhood Hits	217	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NSV0	Gene names	PRR8
Domain Architecture	No domain graphic available
Description	Proline-rich protein 8.

R3HD2_MOUSE
θ value	8.99809 (rank : 118)	NC score	0.022040 (rank : 87)
Query Neighborhood Hits	122	Target Neighborhood Hits	397	Shared Neighborhood Hits	24
SwissProt Accessions	Q80TM6, Q80YB1, Q8BLS5, Q9CW50	Gene names	R3hdm2, Kiaa1002
Domain Architecture
Description	R3H domain-containing protein 2.

SMRC2_MOUSE
θ value	8.99809 (rank : 119)	NC score	0.016230 (rank : 99)
Query Neighborhood Hits	122	Target Neighborhood Hits	487	Shared Neighborhood Hits	16
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

STK11_HUMAN
θ value	8.99809 (rank : 120)	NC score	0.000717 (rank : 129)
Query Neighborhood Hits	122	Target Neighborhood Hits	831	Shared Neighborhood Hits	6
SwissProt Accessions	Q15831	Gene names	STK11, LKB1, PJS
Domain Architecture
Description	Serine/threonine-protein kinase 11 (EC 2.7.11.1) (Serine/threonine- protein kinase LKB1) (NY-REN-19 antigen).

UBP49_MOUSE
θ value	8.99809 (rank : 121)	NC score	0.010096 (rank : 117)
Query Neighborhood Hits	122	Target Neighborhood Hits	91	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P9L4	Gene names	Usp49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

ZC3H6_HUMAN
θ value	8.99809 (rank : 122)	NC score	0.022112 (rank : 85)
Query Neighborhood Hits	122	Target Neighborhood Hits	228	Shared Neighborhood Hits	17
SwissProt Accessions	P61129	Gene names	ZC3H6, KIAA2035, ZC3HDC6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

ATF3_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.084358 (rank : 28)
Query Neighborhood Hits	122	Target Neighborhood Hits	120	Shared Neighborhood Hits	23
SwissProt Accessions	P18847	Gene names	ATF3
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-3 (Activating transcription factor 3).

ATF3_MOUSE
θ value	θ > 10 (rank : 124)	NC score	0.083758 (rank : 29)
Query Neighborhood Hits	122	Target Neighborhood Hits	120	Shared Neighborhood Hits	23
SwissProt Accessions	Q60765	Gene names	Atf3
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-3 (Activating transcription factor 3) (Transcription factor LRG-21).

FOSL1_MOUSE
θ value	θ > 10 (rank : 125)	NC score	0.051574 (rank : 39)
Query Neighborhood Hits	122	Target Neighborhood Hits	113	Shared Neighborhood Hits	13
SwissProt Accessions	P48755, O35285	Gene names	Fosl1, Fra1
Domain Architecture
Description	Fos-related antigen 1 (FRA-1).

JUND_HUMAN
θ value	θ > 10 (rank : 126)	NC score	0.100248 (rank : 22)
Query Neighborhood Hits	122	Target Neighborhood Hits	122	Shared Neighborhood Hits	26
SwissProt Accessions	P17535	Gene names	JUND
Domain Architecture
Description	Transcription factor jun-D.

JUND_MOUSE
θ value	θ > 10 (rank : 127)	NC score	0.098432 (rank : 23)
Query Neighborhood Hits	122	Target Neighborhood Hits	134	Shared Neighborhood Hits	26
SwissProt Accessions	P15066	Gene names	Jund, Jun-d, Jund1
Domain Architecture
Description	Transcription factor jun-D.

JUN_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.097852 (rank : 25)
Query Neighborhood Hits	122	Target Neighborhood Hits	144	Shared Neighborhood Hits	25
SwissProt Accessions	P05412, Q96G93	Gene names	JUN
Domain Architecture
Description	Transcription factor AP-1 (Activator protein 1) (AP1) (Proto-oncogene c-jun) (V-jun avian sarcoma virus 17 oncogene homolog) (p39).

JUN_MOUSE
θ value	θ > 10 (rank : 129)	NC score	0.098123 (rank : 24)
Query Neighborhood Hits	122	Target Neighborhood Hits	145	Shared Neighborhood Hits	25
SwissProt Accessions	P05627	Gene names	Jun
Domain Architecture
Description	Transcription factor AP-1 (Activator protein 1) (AP1) (Proto-oncogene c-jun) (V-jun avian sarcoma virus 17 oncogene homolog) (Jun A) (AH119).

XBP1_HUMAN
θ value	θ > 10 (rank : 130)	NC score	0.094140 (rank : 26)
Query Neighborhood Hits	122	Target Neighborhood Hits	109	Shared Neighborhood Hits	15
SwissProt Accessions	P17861, Q8WYK6, Q969P1, Q96BD7	Gene names	XBP1, TREB5, XBP2
Domain Architecture	No domain graphic available
Description	X box-binding protein 1 (XBP-1) (Tax-responsive element-binding protein 5).

Hits sorted by NC score

ATF6B_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	122	Target Neighborhood Hits	122	Shared Neighborhood Hits	122
SwissProt Accessions	Q99941, Q13269, Q14343, Q14345, Q99635, Q99637, Q9H3V9, Q9H3W1, Q9NPL0	Gene names	CREBL1, G13
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp) (Protein G13).

ATF6B_MOUSE
NC score	0.969067 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	122	Target Neighborhood Hits	97	Shared Neighborhood Hits	44
SwissProt Accessions	O35451	Gene names	Crebl1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp).

ATF6A_HUMAN
NC score	0.848346 (rank : 3)	θ value	6.96618e-77 (rank : 3)
Query Neighborhood Hits	122	Target Neighborhood Hits	174	Shared Neighborhood Hits	37
SwissProt Accessions	P18850, O15139, Q5VW62, Q6IPB5, Q9UEC9	Gene names	ATF6
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 alpha (Activating transcription factor 6 alpha) (ATF6-alpha).

CREB3_MOUSE
NC score	0.367717 (rank : 4)	θ value	1.87187e-05 (rank : 5)
Query Neighborhood Hits	122	Target Neighborhood Hits	97	Shared Neighborhood Hits	25
SwissProt Accessions	Q61817, Q99M21, Q9CVK9	Gene names	Creb3, Lzip
Domain Architecture	No domain graphic available
Description	Cyclic AMP-responsive element-binding protein 3 (Transcription factor LZIP).

CREB3_HUMAN
NC score	0.360808 (rank : 5)	θ value	1.09739e-05 (rank : 4)
Query Neighborhood Hits	122	Target Neighborhood Hits	138	Shared Neighborhood Hits	27
SwissProt Accessions	O43889, O14671, O14919, Q96GK8, Q9H2W3, Q9UE77	Gene names	CREB3, LZIP
Domain Architecture	No domain graphic available
Description	Cyclic AMP-responsive element-binding protein 3 (Luman protein) (Transcription factor LZIP-alpha).

ATF1_HUMAN
NC score	0.349946 (rank : 6)	θ value	9.29e-05 (rank : 8)
Query Neighborhood Hits	122	Target Neighborhood Hits	59	Shared Neighborhood Hits	21
SwissProt Accessions	P18846, P25168	Gene names	ATF1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-1 (Activating transcription factor 1) (TREB36 protein).

ATF1_MOUSE
NC score	0.343333 (rank : 7)	θ value	0.00035302 (rank : 9)
Query Neighborhood Hits	122	Target Neighborhood Hits	70	Shared Neighborhood Hits	21
SwissProt Accessions	P81269	Gene names	Atf1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-1 (Activating transcription factor 1) (TCR-ATF1).

CREM_HUMAN
NC score	0.335952 (rank : 8)	θ value	4.1701e-05 (rank : 6)
Query Neighborhood Hits	122	Target Neighborhood Hits	63	Shared Neighborhood Hits	19
SwissProt Accessions	Q03060, Q16114, Q16116, Q9NZB9	Gene names	CREM
Domain Architecture
Description	cAMP-responsive element modulator.

CREM_MOUSE
NC score	0.333431 (rank : 9)	θ value	5.44631e-05 (rank : 7)
Query Neighborhood Hits	122	Target Neighborhood Hits	58	Shared Neighborhood Hits	19
SwissProt Accessions	P27699, P27698	Gene names	Crem
Domain Architecture
Description	cAMP-responsive element modulator.

CREB1_MOUSE
NC score	0.310759 (rank : 10)	θ value	0.00228821 (rank : 14)
Query Neighborhood Hits	122	Target Neighborhood Hits	58	Shared Neighborhood Hits	20
SwissProt Accessions	Q01147	Gene names	Creb1, Creb-1
Domain Architecture
Description	cAMP response element-binding protein (CREB).

CREB1_HUMAN
NC score	0.310746 (rank : 11)	θ value	0.00228821 (rank : 13)
Query Neighborhood Hits	122	Target Neighborhood Hits	57	Shared Neighborhood Hits	20
SwissProt Accessions	P16220, P21934, Q9UMA7	Gene names	CREB1
Domain Architecture
Description	cAMP response element-binding protein (CREB).

ZHANG_MOUSE
NC score	0.301379 (rank : 12)	θ value	0.00134147 (rank : 11)
Query Neighborhood Hits	122	Target Neighborhood Hits	20	Shared Neighborhood Hits	8
SwissProt Accessions	Q91ZR3, Q91Y72	Gene names	Zf
Domain Architecture	No domain graphic available
Description	Host cell factor-binding transcription factor Zhangfei (HCF-binding transcription factor Zhangfei) (Tyrosine kinase-associated leucine zipper protein LAZip).

ZHANG_HUMAN
NC score	0.301277 (rank : 13)	θ value	0.00134147 (rank : 10)
Query Neighborhood Hits	122	Target Neighborhood Hits	24	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NS37	Gene names	ZF
Domain Architecture	No domain graphic available
Description	Host cell factor-binding transcription factor Zhangfei (HCF-binding transcription factor Zhangfei).

ATF7_HUMAN
NC score	0.181528 (rank : 14)	θ value	0.0252991 (rank : 15)
Query Neighborhood Hits	122	Target Neighborhood Hits	333	Shared Neighborhood Hits	30
SwissProt Accessions	P17544, Q13814	Gene names	ATF7, ATFA
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

ATF7_MOUSE
NC score	0.181357 (rank : 15)	θ value	0.0252991 (rank : 16)
Query Neighborhood Hits	122	Target Neighborhood Hits	286	Shared Neighborhood Hits	28
SwissProt Accessions	Q8R0S1	Gene names	Atf7
Domain Architecture	No domain graphic available
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

XBP1_MOUSE
NC score	0.173235 (rank : 16)	θ value	0.0563607 (rank : 18)
Query Neighborhood Hits	122	Target Neighborhood Hits	99	Shared Neighborhood Hits	13
SwissProt Accessions	O35426, Q8VHM0, Q922G5, Q9ESS3	Gene names	Xbp1, Treb5
Domain Architecture	No domain graphic available
Description	X box-binding protein 1 (XBP-1) (Tax-responsive element-binding protein 5 homolog).

ATF2_HUMAN
NC score	0.153451 (rank : 17)	θ value	0.21417 (rank : 23)
Query Neighborhood Hits	122	Target Neighborhood Hits	402	Shared Neighborhood Hits	32
SwissProt Accessions	P15336, Q13000	Gene names	ATF2, CREB2, CREBP1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (HB16).

ATF2_MOUSE
NC score	0.151952 (rank : 18)	θ value	0.21417 (rank : 24)
Query Neighborhood Hits	122	Target Neighborhood Hits	397	Shared Neighborhood Hits	32
SwissProt Accessions	P16951, Q64089, Q64090, Q64091	Gene names	Atf2
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (MXBP protein).

CREB5_HUMAN
NC score	0.150139 (rank : 19)	θ value	2.36792 (rank : 54)
Query Neighborhood Hits	122	Target Neighborhood Hits	222	Shared Neighborhood Hits	25
SwissProt Accessions	Q02930, Q05886, Q06246	Gene names	CREB5, CREBPA
Domain Architecture
Description	cAMP response element-binding protein 5 (CRE-BPa).

JUNB_HUMAN
NC score	0.131924 (rank : 20)	θ value	0.365318 (rank : 29)
Query Neighborhood Hits	122	Target Neighborhood Hits	97	Shared Neighborhood Hits	24
SwissProt Accessions	P17275, Q96GH3	Gene names	JUNB
Domain Architecture
Description	Transcription factor jun-B.

JUNB_MOUSE
NC score	0.129316 (rank : 21)	θ value	0.365318 (rank : 30)
Query Neighborhood Hits	122	Target Neighborhood Hits	116	Shared Neighborhood Hits	24
SwissProt Accessions	P09450, Q8C2G9	Gene names	Junb, Jun-b
Domain Architecture
Description	Transcription factor jun-B.

JUND_HUMAN
NC score	0.100248 (rank : 22)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	122	Target Neighborhood Hits	122	Shared Neighborhood Hits	26
SwissProt Accessions	P17535	Gene names	JUND
Domain Architecture
Description	Transcription factor jun-D.

JUND_MOUSE
NC score	0.098432 (rank : 23)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	122	Target Neighborhood Hits	134	Shared Neighborhood Hits	26
SwissProt Accessions	P15066	Gene names	Jund, Jun-d, Jund1
Domain Architecture
Description	Transcription factor jun-D.

JUN_MOUSE
NC score	0.098123 (rank : 24)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	122	Target Neighborhood Hits	145	Shared Neighborhood Hits	25
SwissProt Accessions	P05627	Gene names	Jun
Domain Architecture
Description	Transcription factor AP-1 (Activator protein 1) (AP1) (Proto-oncogene c-jun) (V-jun avian sarcoma virus 17 oncogene homolog) (Jun A) (AH119).

JUN_HUMAN
NC score	0.097852 (rank : 25)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	122	Target Neighborhood Hits	144	Shared Neighborhood Hits	25
SwissProt Accessions	P05412, Q96G93	Gene names	JUN
Domain Architecture
Description	Transcription factor AP-1 (Activator protein 1) (AP1) (Proto-oncogene c-jun) (V-jun avian sarcoma virus 17 oncogene homolog) (p39).

XBP1_HUMAN
NC score	0.094140 (rank : 26)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	122	Target Neighborhood Hits	109	Shared Neighborhood Hits	15
SwissProt Accessions	P17861, Q8WYK6, Q969P1, Q96BD7	Gene names	XBP1, TREB5, XBP2
Domain Architecture	No domain graphic available
Description	X box-binding protein 1 (XBP-1) (Tax-responsive element-binding protein 5).

CDC37_HUMAN
NC score	0.086394 (rank : 27)	θ value	0.0563607 (rank : 17)
Query Neighborhood Hits	122	Target Neighborhood Hits	506	Shared Neighborhood Hits	12
SwissProt Accessions	Q16543	Gene names	CDC37
Domain Architecture
Description	Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37).

ATF3_HUMAN
NC score	0.084358 (rank : 28)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	122	Target Neighborhood Hits	120	Shared Neighborhood Hits	23
SwissProt Accessions	P18847	Gene names	ATF3
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-3 (Activating transcription factor 3).

ATF3_MOUSE
NC score	0.083758 (rank : 29)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	122	Target Neighborhood Hits	120	Shared Neighborhood Hits	23
SwissProt Accessions	Q60765	Gene names	Atf3
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-3 (Activating transcription factor 3) (Transcription factor LRG-21).

PCQAP_HUMAN
NC score	0.083383 (rank : 30)	θ value	0.0736092 (rank : 19)
Query Neighborhood Hits	122	Target Neighborhood Hits	549	Shared Neighborhood Hits	28
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

ATF5_MOUSE
NC score	0.079382 (rank : 31)	θ value	0.125558 (rank : 22)
Query Neighborhood Hits	122	Target Neighborhood Hits	62	Shared Neighborhood Hits	11
SwissProt Accessions	O70191, Q58E51, Q99NH6	Gene names	Atf5, Atfx, Nap1
Domain Architecture	No domain graphic available
Description	Cyclic AMP-dependent transcription factor ATF-5 (Activating transcription factor 5-alpha/beta) (Transcription factor ATFx) (Transcription factor-like protein ODA-10) (BZIP protein ATF7) (NRIF3- associated protein) (NAP1).

PCQAP_MOUSE
NC score	0.068033 (rank : 32)	θ value	0.365318 (rank : 31)
Query Neighborhood Hits	122	Target Neighborhood Hits	506	Shared Neighborhood Hits	24
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

K1543_MOUSE
NC score	0.061296 (rank : 33)	θ value	0.279714 (rank : 26)
Query Neighborhood Hits	122	Target Neighborhood Hits	497	Shared Neighborhood Hits	29
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

BAT2_HUMAN
NC score	0.056401 (rank : 34)	θ value	0.813845 (rank : 33)
Query Neighborhood Hits	122	Target Neighborhood Hits	931	Shared Neighborhood Hits	44
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

MDC1_MOUSE
NC score	0.054582 (rank : 35)	θ value	1.06291 (rank : 38)
Query Neighborhood Hits	122	Target Neighborhood Hits	998	Shared Neighborhood Hits	47
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

BATF_MOUSE
NC score	0.052646 (rank : 36)	θ value	6.88961 (rank : 91)
Query Neighborhood Hits	122	Target Neighborhood Hits	100	Shared Neighborhood Hits	13
SwissProt Accessions	O35284	Gene names	Batf
Domain Architecture
Description	ATF-like basic leucine zipper transcription factor B-ATF.

RIMB1_MOUSE
NC score	0.052110 (rank : 37)	θ value	0.0961366 (rank : 21)
Query Neighborhood Hits	122	Target Neighborhood Hits	1376	Shared Neighborhood Hits	36
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

BAZ2A_MOUSE
NC score	0.051765 (rank : 38)	θ value	0.279714 (rank : 25)
Query Neighborhood Hits	122	Target Neighborhood Hits	744	Shared Neighborhood Hits	41
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

FOSL1_MOUSE
NC score	0.051574 (rank : 39)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	122	Target Neighborhood Hits	113	Shared Neighborhood Hits	13
SwissProt Accessions	P48755, O35285	Gene names	Fosl1, Fra1
Domain Architecture
Description	Fos-related antigen 1 (FRA-1).

MAP4_MOUSE
NC score	0.048231 (rank : 40)	θ value	0.279714 (rank : 27)
Query Neighborhood Hits	122	Target Neighborhood Hits	409	Shared Neighborhood Hits	19
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MELPH_HUMAN
NC score	0.047710 (rank : 41)	θ value	1.06291 (rank : 39)
Query Neighborhood Hits	122	Target Neighborhood Hits	145	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BV36, Q9HA71	Gene names	MLPH, SLAC2A
Domain Architecture	No domain graphic available
Description	Melanophilin (Exophilin-3) (Synaptotagmin-like protein 2a) (Slp homolog lacking C2 domains a).

MUC1_HUMAN
NC score	0.044832 (rank : 42)	θ value	0.279714 (rank : 28)
Query Neighborhood Hits	122	Target Neighborhood Hits	975	Shared Neighborhood Hits	44
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

WBP11_MOUSE
NC score	0.044658 (rank : 43)	θ value	2.36792 (rank : 60)
Query Neighborhood Hits	122	Target Neighborhood Hits	362	Shared Neighborhood Hits	18
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

WBP11_HUMAN
NC score	0.044575 (rank : 44)	θ value	2.36792 (rank : 59)
Query Neighborhood Hits	122	Target Neighborhood Hits	354	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

BAT2_MOUSE
NC score	0.043584 (rank : 45)	θ value	4.03905 (rank : 69)
Query Neighborhood Hits	122	Target Neighborhood Hits	947	Shared Neighborhood Hits	45
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

RIMB1_HUMAN
NC score	0.043550 (rank : 46)	θ value	1.38821 (rank : 43)
Query Neighborhood Hits	122	Target Neighborhood Hits	1479	Shared Neighborhood Hits	43
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

MAFB_MOUSE
NC score	0.040873 (rank : 47)	θ value	8.99809 (rank : 112)
Query Neighborhood Hits	122	Target Neighborhood Hits	92	Shared Neighborhood Hits	16
SwissProt Accessions	P54841	Gene names	Mafb, Krml, Maf1
Domain Architecture
Description	Transcription factor MafB (V-maf musculoaponeurotic fibrosarcoma oncogene homolog B) (Transcription factor MAF1) (Segmentation protein KR) (Kreisler).

RFIP3_HUMAN
NC score	0.040584 (rank : 48)	θ value	0.813845 (rank : 36)
Query Neighborhood Hits	122	Target Neighborhood Hits	1055	Shared Neighborhood Hits	34
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

MAFF_MOUSE
NC score	0.040252 (rank : 49)	θ value	8.99809 (rank : 114)
Query Neighborhood Hits	122	Target Neighborhood Hits	53	Shared Neighborhood Hits	13
SwissProt Accessions	O54791	Gene names	Maff
Domain Architecture
Description	Transcription factor MafF (V-maf musculoaponeurotic fibrosarcoma oncogene homolog F).

MAD4_MOUSE
NC score	0.039827 (rank : 50)	θ value	3.0926 (rank : 63)
Query Neighborhood Hits	122	Target Neighborhood Hits	65	Shared Neighborhood Hits	7
SwissProt Accessions	Q60948	Gene names	Mxd4, Mad4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

MEGF9_HUMAN
NC score	0.039584 (rank : 51)	θ value	0.00175202 (rank : 12)
Query Neighborhood Hits	122	Target Neighborhood Hits	557	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MAFB_HUMAN
NC score	0.039468 (rank : 52)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	122	Target Neighborhood Hits	96	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y5Q3, Q9H1F1	Gene names	MAFB, KRML
Domain Architecture
Description	Transcription factor MafB (V-maf musculoaponeurotic fibrosarcoma oncogene homolog B).

MAFF_HUMAN
NC score	0.039279 (rank : 53)	θ value	8.99809 (rank : 113)
Query Neighborhood Hits	122	Target Neighborhood Hits	54	Shared Neighborhood Hits	13
SwissProt Accessions	Q9ULX9, Q9Y525	Gene names	MAFF
Domain Architecture
Description	Transcription factor MafF (V-maf musculoaponeurotic fibrosarcoma oncogene homolog F) (U-Maf).

MADCA_HUMAN
NC score	0.038935 (rank : 54)	θ value	2.36792 (rank : 57)
Query Neighborhood Hits	122	Target Neighborhood Hits	221	Shared Neighborhood Hits	17
SwissProt Accessions	Q13477, O60222, O75867	Gene names	MADCAM1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (hMAdCAM-1).

SON_HUMAN
NC score	0.038717 (rank : 55)	θ value	3.0926 (rank : 67)
Query Neighborhood Hits	122	Target Neighborhood Hits	1568	Shared Neighborhood Hits	63
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

BAT3_MOUSE
NC score	0.038679 (rank : 56)	θ value	3.0926 (rank : 61)
Query Neighborhood Hits	122	Target Neighborhood Hits	518	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

MLL3_HUMAN
NC score	0.037589 (rank : 57)	θ value	8.99809 (rank : 116)
Query Neighborhood Hits	122	Target Neighborhood Hits	1644	Shared Neighborhood Hits	67
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

WASIP_MOUSE
NC score	0.037435 (rank : 58)	θ value	4.03905 (rank : 77)
Query Neighborhood Hits	122	Target Neighborhood Hits	392	Shared Neighborhood Hits	25
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

DIAP1_MOUSE
NC score	0.035837 (rank : 59)	θ value	0.0961366 (rank : 20)
Query Neighborhood Hits	122	Target Neighborhood Hits	839	Shared Neighborhood Hits	27
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

RTP3_MOUSE
NC score	0.034566 (rank : 60)	θ value	1.81305 (rank : 50)
Query Neighborhood Hits	122	Target Neighborhood Hits	374	Shared Neighborhood Hits	23
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

HEBP2_MOUSE
NC score	0.034537 (rank : 61)	θ value	1.81305 (rank : 44)
Query Neighborhood Hits	122	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WU63	Gene names	Hebp2, Soul
Domain Architecture	No domain graphic available
Description	Heme-binding protein 2 (Protein SOUL).

PODXL_HUMAN
NC score	0.033556 (rank : 62)	θ value	4.03905 (rank : 72)
Query Neighborhood Hits	122	Target Neighborhood Hits	191	Shared Neighborhood Hits	12
SwissProt Accessions	O00592	Gene names	PODXL, PCLP, PCLP1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

SPAG5_HUMAN
NC score	0.033377 (rank : 63)	θ value	0.813845 (rank : 37)
Query Neighborhood Hits	122	Target Neighborhood Hits	625	Shared Neighborhood Hits	19
SwissProt Accessions	Q96R06, O95213, Q9BWE8, Q9NT17, Q9UFE6	Gene names	SPAG5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Astrin) (Mitotic spindle-associated protein p126) (MAP126) (Deepest).

SATB2_HUMAN
NC score	0.030981 (rank : 64)	θ value	4.03905 (rank : 75)
Query Neighborhood Hits	122	Target Neighborhood Hits	58	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UPW6	Gene names	SATB2, KIAA1034
Domain Architecture
Description	DNA-binding protein SATB2 (Special AT-rich sequence-binding protein 2).

SATB2_MOUSE
NC score	0.030978 (rank : 65)	θ value	4.03905 (rank : 76)
Query Neighborhood Hits	122	Target Neighborhood Hits	58	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VI24	Gene names	Satb2, Kiaa1034
Domain Architecture
Description	DNA-binding protein SATB2 (Special AT-rich sequence-binding protein 2).

ALEX_MOUSE
NC score	0.030914 (rank : 66)	θ value	4.03905 (rank : 68)
Query Neighborhood Hits	122	Target Neighborhood Hits	197	Shared Neighborhood Hits	15
SwissProt Accessions	Q6R0H6, Q8BIR3	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

WASP_HUMAN
NC score	0.029973 (rank : 67)	θ value	1.81305 (rank : 52)
Query Neighborhood Hits	122	Target Neighborhood Hits	195	Shared Neighborhood Hits	17
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

SATB1_HUMAN
NC score	0.029830 (rank : 68)	θ value	5.27518 (rank : 87)
Query Neighborhood Hits	122	Target Neighborhood Hits	130	Shared Neighborhood Hits	10
SwissProt Accessions	Q01826	Gene names	SATB1
Domain Architecture
Description	DNA-binding protein SATB1 (Special AT-rich sequence-binding protein 1).

NDE1_HUMAN
NC score	0.029665 (rank : 69)	θ value	0.813845 (rank : 35)
Query Neighborhood Hits	122	Target Neighborhood Hits	823	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NXR1, Q49AQ2	Gene names	NDE1, NUDE
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE).

GGN_HUMAN
NC score	0.029661 (rank : 70)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	122	Target Neighborhood Hits	269	Shared Neighborhood Hits	15
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

MLL3_MOUSE
NC score	0.029389 (rank : 71)	θ value	3.0926 (rank : 64)
Query Neighborhood Hits	122	Target Neighborhood Hits	1399	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

FMN2_HUMAN
NC score	0.028704 (rank : 72)	θ value	5.27518 (rank : 82)
Query Neighborhood Hits	122	Target Neighborhood Hits	484	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

PRR8_HUMAN
NC score	0.027684 (rank : 73)	θ value	8.99809 (rank : 117)
Query Neighborhood Hits	122	Target Neighborhood Hits	217	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NSV0	Gene names	PRR8
Domain Architecture	No domain graphic available
Description	Proline-rich protein 8.

FMNL_HUMAN
NC score	0.027542 (rank : 74)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	122	Target Neighborhood Hits	529	Shared Neighborhood Hits	30
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

PCLO_HUMAN
NC score	0.027509 (rank : 75)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	122	Target Neighborhood Hits	2046	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

HOOK1_MOUSE
NC score	0.026368 (rank : 76)	θ value	1.81305 (rank : 45)
Query Neighborhood Hits	122	Target Neighborhood Hits	910	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BIL5, Q8BIZ2, Q8K0P1, Q8K454, Q9CTN6	Gene names	Hook1
Domain Architecture
Description	Hook homolog 1.

UROL1_HUMAN
NC score	0.026356 (rank : 77)	θ value	1.06291 (rank : 41)
Query Neighborhood Hits	122	Target Neighborhood Hits	213	Shared Neighborhood Hits	3
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

NCOR1_HUMAN
NC score	0.026079 (rank : 78)	θ value	2.36792 (rank : 58)
Query Neighborhood Hits	122	Target Neighborhood Hits	577	Shared Neighborhood Hits	21
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

SEPT9_HUMAN
NC score	0.025810 (rank : 79)	θ value	3.0926 (rank : 66)
Query Neighborhood Hits	122	Target Neighborhood Hits	706	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

MAD4_HUMAN
NC score	0.025147 (rank : 80)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	122	Target Neighborhood Hits	94	Shared Neighborhood Hits	8
SwissProt Accessions	Q14582, Q5TZX4	Gene names	MXD4, MAD4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

SET1A_HUMAN
NC score	0.024618 (rank : 81)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	122	Target Neighborhood Hits	690	Shared Neighborhood Hits	27
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

MAP1A_HUMAN
NC score	0.023919 (rank : 82)	θ value	5.27518 (rank : 85)
Query Neighborhood Hits	122	Target Neighborhood Hits	1626	Shared Neighborhood Hits	52
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

RTN4_HUMAN
NC score	0.023875 (rank : 83)	θ value	3.0926 (rank : 65)
Query Neighborhood Hits	122	Target Neighborhood Hits	357	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

TP53B_MOUSE
NC score	0.023235 (rank : 84)	θ value	6.88961 (rank : 100)
Query Neighborhood Hits	122	Target Neighborhood Hits	644	Shared Neighborhood Hits	26
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

ZC3H6_HUMAN
NC score	0.022112 (rank : 85)	θ value	8.99809 (rank : 122)
Query Neighborhood Hits	122	Target Neighborhood Hits	228	Shared Neighborhood Hits	17
SwissProt Accessions	P61129	Gene names	ZC3H6, KIAA2035, ZC3HDC6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

HOOK1_HUMAN
NC score	0.022081 (rank : 86)	θ value	5.27518 (rank : 84)
Query Neighborhood Hits	122	Target Neighborhood Hits	942	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

R3HD2_MOUSE
NC score	0.022040 (rank : 87)	θ value	8.99809 (rank : 118)
Query Neighborhood Hits	122	Target Neighborhood Hits	397	Shared Neighborhood Hits	24
SwissProt Accessions	Q80TM6, Q80YB1, Q8BLS5, Q9CW50	Gene names	R3hdm2, Kiaa1002
Domain Architecture
Description	R3H domain-containing protein 2.

PARD3_MOUSE
NC score	0.021290 (rank : 88)	θ value	0.62314 (rank : 32)
Query Neighborhood Hits	122	Target Neighborhood Hits	290	Shared Neighborhood Hits	7
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

LR37B_HUMAN
NC score	0.020857 (rank : 89)	θ value	2.36792 (rank : 56)
Query Neighborhood Hits	122	Target Neighborhood Hits	392	Shared Neighborhood Hits	13
SwissProt Accessions	Q96QE4, Q5YKG6	Gene names	LRRC37B
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37B precursor (C66 SLIT-like testicular protein).

TBC10_HUMAN
NC score	0.020748 (rank : 90)	θ value	1.81305 (rank : 51)
Query Neighborhood Hits	122	Target Neighborhood Hits	64	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BXI6, O76053, Q543A2	Gene names	TBC1D10A, EPI64, TBC1D10
Domain Architecture
Description	TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa) (EPI64 protein).

RC3H1_HUMAN
NC score	0.020121 (rank : 91)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	122	Target Neighborhood Hits	433	Shared Neighborhood Hits	22
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

MYCB2_HUMAN
NC score	0.020038 (rank : 92)	θ value	1.81305 (rank : 47)
Query Neighborhood Hits	122	Target Neighborhood Hits	390	Shared Neighborhood Hits	5
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

CDX2_MOUSE
NC score	0.019163 (rank : 93)	θ value	0.813845 (rank : 34)
Query Neighborhood Hits	122	Target Neighborhood Hits	336	Shared Neighborhood Hits	9
SwissProt Accessions	P43241	Gene names	Cdx2, Cdx-2
Domain Architecture
Description	Homeobox protein CDX-2 (Caudal-type homeobox protein 2).

CI039_HUMAN
NC score	0.018089 (rank : 94)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	122	Target Neighborhood Hits	1171	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

CDX2_HUMAN
NC score	0.017422 (rank : 95)	θ value	1.38821 (rank : 42)
Query Neighborhood Hits	122	Target Neighborhood Hits	330	Shared Neighborhood Hits	7
SwissProt Accessions	Q99626, O00503, Q969L8	Gene names	CDX2, CDX3
Domain Architecture
Description	Homeobox protein CDX-2 (Caudal-type homeobox protein 2) (CDX-3).

AB1IP_MOUSE
NC score	0.017116 (rank : 96)	θ value	5.27518 (rank : 78)
Query Neighborhood Hits	122	Target Neighborhood Hits	181	Shared Neighborhood Hits	12
SwissProt Accessions	Q8R5A3, O35329, Q8BRU0, Q99KV8	Gene names	Apbb1ip, Prel1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 48).

GON4L_HUMAN
NC score	0.016929 (rank : 97)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	122	Target Neighborhood Hits	555	Shared Neighborhood Hits	23
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

TUFT1_MOUSE
NC score	0.016542 (rank : 98)	θ value	5.27518 (rank : 88)
Query Neighborhood Hits	122	Target Neighborhood Hits	732	Shared Neighborhood Hits	23
SwissProt Accessions	O08970	Gene names	Tuft1
Domain Architecture
Description	Tuftelin.

SMRC2_MOUSE
NC score	0.016230 (rank : 99)	θ value	8.99809 (rank : 119)
Query Neighborhood Hits	122	Target Neighborhood Hits	487	Shared Neighborhood Hits	16
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

CSKI1_HUMAN
NC score	0.016138 (rank : 100)	θ value	2.36792 (rank : 55)
Query Neighborhood Hits	122	Target Neighborhood Hits	997	Shared Neighborhood Hits	36
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

PRA12_HUMAN
NC score	0.014941 (rank : 101)	θ value	1.81305 (rank : 49)
Query Neighborhood Hits	122	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	O95522	Gene names
Domain Architecture	No domain graphic available
Description	PRAME family member DJ1198H6.2.

SHAN1_HUMAN
NC score	0.014883 (rank : 102)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	122	Target Neighborhood Hits	1041	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

RAVR2_HUMAN
NC score	0.014527 (rank : 103)	θ value	4.03905 (rank : 73)
Query Neighborhood Hits	122	Target Neighborhood Hits	144	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HCJ3, Q6P141, Q9NPV7	Gene names	RAVER2, KIAA1579
Domain Architecture	No domain graphic available
Description	Ribonucleoprotein PTB-binding 2 (Protein raver-2).

KCNN3_HUMAN
NC score	0.014410 (rank : 104)	θ value	4.03905 (rank : 71)
Query Neighborhood Hits	122	Target Neighborhood Hits	216	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UGI6, O43517	Gene names	KCNN3, K3
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 3 (SK3) (SKCa3).

DDEF2_HUMAN
NC score	0.014250 (rank : 105)	θ value	4.03905 (rank : 70)
Query Neighborhood Hits	122	Target Neighborhood Hits	599	Shared Neighborhood Hits	22
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

HMMR_MOUSE
NC score	0.013632 (rank : 106)	θ value	5.27518 (rank : 83)
Query Neighborhood Hits	122	Target Neighborhood Hits	1178	Shared Neighborhood Hits	24
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

CDX1_MOUSE
NC score	0.013543 (rank : 107)	θ value	5.27518 (rank : 80)
Query Neighborhood Hits	122	Target Neighborhood Hits	379	Shared Neighborhood Hits	14
SwissProt Accessions	P18111, Q8VCF7	Gene names	Cdx1, Cdx-1
Domain Architecture
Description	Homeobox protein CDX-1 (Caudal-type homeobox protein 1).

P3C2B_HUMAN
NC score	0.013031 (rank : 108)	θ value	1.81305 (rank : 48)
Query Neighborhood Hits	122	Target Neighborhood Hits	148	Shared Neighborhood Hits	5
SwissProt Accessions	O00750, O95666, Q5SW99	Gene names	PIK3C2B
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-beta) (PtdIns-3-kinase C2 beta) (PI3K-C2beta) (C2-PI3K).

ELK1_HUMAN
NC score	0.012601 (rank : 109)	θ value	3.0926 (rank : 62)
Query Neighborhood Hits	122	Target Neighborhood Hits	112	Shared Neighborhood Hits	6
SwissProt Accessions	P19419, O75606, O95058, Q969X8, Q9UJM4	Gene names	ELK1
Domain Architecture
Description	ETS domain-containing protein Elk-1.

HCLS1_HUMAN
NC score	0.011812 (rank : 110)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	122	Target Neighborhood Hits	358	Shared Neighborhood Hits	17
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

HD_HUMAN
NC score	0.011807 (rank : 111)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	122	Target Neighborhood Hits	165	Shared Neighborhood Hits	6
SwissProt Accessions	P42858, Q9UQB7	Gene names	HD, IT15
Domain Architecture
Description	Huntingtin (Huntington disease protein) (HD protein).

UBP49_HUMAN
NC score	0.011607 (rank : 112)	θ value	5.27518 (rank : 89)
Query Neighborhood Hits	122	Target Neighborhood Hits	100	Shared Neighborhood Hits	3
SwissProt Accessions	Q70CQ1, Q96CK4	Gene names	USP49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

SYNE2_HUMAN
NC score	0.011280 (rank : 113)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	122	Target Neighborhood Hits	1323	Shared Neighborhood Hits	28
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

GGA1_HUMAN
NC score	0.011000 (rank : 114)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	122	Target Neighborhood Hits	169	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UJY5, Q5TG07, Q9BW94, Q9UG00, Q9UGW0, Q9UGW1	Gene names	GGA1
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

TOP2A_HUMAN
NC score	0.010989 (rank : 115)	θ value	6.88961 (rank : 99)
Query Neighborhood Hits	122	Target Neighborhood Hits	135	Shared Neighborhood Hits	5
SwissProt Accessions	P11388, Q71UN1, Q9HB24, Q9HB25, Q9HB26, Q9UP44, Q9UQP9	Gene names	TOP2A, TOP2
Domain Architecture
Description	DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme).

TREF1_HUMAN
NC score	0.010882 (rank : 116)	θ value	6.88961 (rank : 101)
Query Neighborhood Hits	122	Target Neighborhood Hits	651	Shared Neighborhood Hits	13
SwissProt Accessions	Q96PN7, Q7Z6T2, Q7Z6T3, Q9NQ72, Q9NQ73, Q9NUN9	Gene names	TRERF1, RAPA, TREP132
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132) (Zinc finger protein rapa).

UBP49_MOUSE
NC score	0.010096 (rank : 117)	θ value	8.99809 (rank : 121)
Query Neighborhood Hits	122	Target Neighborhood Hits	91	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P9L4	Gene names	Usp49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

MRCKB_MOUSE
NC score	0.009977 (rank : 118)	θ value	5.27518 (rank : 86)
Query Neighborhood Hits	122	Target Neighborhood Hits	2180	Shared Neighborhood Hits	38
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

LAMA2_MOUSE
NC score	0.009240 (rank : 119)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	122	Target Neighborhood Hits	1198	Shared Neighborhood Hits	17
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

ATBF1_HUMAN
NC score	0.008977 (rank : 120)	θ value	5.27518 (rank : 79)
Query Neighborhood Hits	122	Target Neighborhood Hits	1547	Shared Neighborhood Hits	32
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

MEF2A_HUMAN
NC score	0.008326 (rank : 121)	θ value	8.99809 (rank : 115)
Query Neighborhood Hits	122	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	Q02078, O43814, Q14223, Q14224, Q96D14	Gene names	MEF2A, MEF2
Domain Architecture
Description	Myocyte-specific enhancer factor 2A (Serum response factor-like protein 1).

HXA10_MOUSE
NC score	0.008313 (rank : 122)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	122	Target Neighborhood Hits	365	Shared Neighborhood Hits	11
SwissProt Accessions	P31310, Q80Y22	Gene names	Hoxa10, Hox-1.8, Hoxa-10
Domain Architecture
Description	Homeobox protein Hox-A10 (Hox-1.8).

TITIN_HUMAN
NC score	0.008257 (rank : 123)	θ value	1.06291 (rank : 40)
Query Neighborhood Hits	122	Target Neighborhood Hits	2923	Shared Neighborhood Hits	49
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

HLX1_HUMAN
NC score	0.007809 (rank : 124)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	122	Target Neighborhood Hits	370	Shared Neighborhood Hits	8
SwissProt Accessions	Q14774, Q15988	Gene names	HLX1
Domain Architecture
Description	Homeobox protein HLX1 (Homeobox protein HB24).

GAK8_HUMAN
NC score	0.006123 (rank : 125)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	122	Target Neighborhood Hits	145	Shared Neighborhood Hits	13
SwissProt Accessions	Q9HDB9	Gene names	ERVK5
Domain Architecture	No domain graphic available
Description	HERV-K_3q12.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(II) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

MK07_HUMAN
NC score	0.005267 (rank : 126)	θ value	1.81305 (rank : 46)
Query Neighborhood Hits	122	Target Neighborhood Hits	1087	Shared Neighborhood Hits	21
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

FOG1_MOUSE
NC score	0.004953 (rank : 127)	θ value	8.99809 (rank : 103)
Query Neighborhood Hits	122	Target Neighborhood Hits	1237	Shared Neighborhood Hits	30
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

CD2L7_HUMAN
NC score	0.004922 (rank : 128)	θ value	2.36792 (rank : 53)
Query Neighborhood Hits	122	Target Neighborhood Hits	1275	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

STK11_HUMAN
NC score	0.000717 (rank : 129)	θ value	8.99809 (rank : 120)
Query Neighborhood Hits	122	Target Neighborhood Hits	831	Shared Neighborhood Hits	6
SwissProt Accessions	Q15831	Gene names	STK11, LKB1, PJS
Domain Architecture
Description	Serine/threonine-protein kinase 11 (EC 2.7.11.1) (Serine/threonine- protein kinase LKB1) (NY-REN-19 antigen).

ZN282_HUMAN
NC score	-0.001286 (rank : 130)	θ value	5.27518 (rank : 90)
Query Neighborhood Hits	122	Target Neighborhood Hits	796	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UDV7, O43691, Q6DKK0	Gene names	ZNF282, HUB1
Domain Architecture
Description	Zinc finger protein 282 (HTLV-I U5RE-binding protein 1) (HUB-1).