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Network neighborhood for query Sequence : PARD3_MOUSE

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PARD3_MOUSE
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PARD3_HUMAN
θ value	0 (rank : 1)	NC score	0.989551 (rank : 2)
Query Neighborhood Hits	290	Target Neighborhood Hits	312	Shared Neighborhood Hits	238
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

PARD3_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	290	Target Neighborhood Hits	290	Shared Neighborhood Hits	290
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

PAR3L_HUMAN
θ value	5.41814e-138 (rank : 3)	NC score	0.936136 (rank : 3)
Query Neighborhood Hits	290	Target Neighborhood Hits	297	Shared Neighborhood Hits	154
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

MPDZ_MOUSE
θ value	4.01107e-24 (rank : 4)	NC score	0.793894 (rank : 5)
Query Neighborhood Hits	290	Target Neighborhood Hits	298	Shared Neighborhood Hits	167
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

INADL_HUMAN
θ value	1.5242e-23 (rank : 5)	NC score	0.792939 (rank : 6)
Query Neighborhood Hits	290	Target Neighborhood Hits	260	Shared Neighborhood Hits	164
SwissProt Accessions	Q8NI35, O15249, O43742, O60833, Q5VUA5, Q5VUA6, Q5VUA7, Q5VUA8, Q5VUA9, Q5VUB0, Q8WU78, Q9H3N9	Gene names	INADL, PATJ
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions).

INADL_MOUSE
θ value	1.5242e-23 (rank : 6)	NC score	0.791858 (rank : 7)
Query Neighborhood Hits	290	Target Neighborhood Hits	290	Shared Neighborhood Hits	170
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

MPDZ_HUMAN
θ value	1.5242e-23 (rank : 7)	NC score	0.796418 (rank : 4)
Query Neighborhood Hits	290	Target Neighborhood Hits	261	Shared Neighborhood Hits	170
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

PTN13_MOUSE
θ value	3.88503e-19 (rank : 8)	NC score	0.442625 (rank : 96)
Query Neighborhood Hits	290	Target Neighborhood Hits	426	Shared Neighborhood Hits	171
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

PTN13_HUMAN
θ value	8.65492e-19 (rank : 9)	NC score	0.456150 (rank : 93)
Query Neighborhood Hits	290	Target Neighborhood Hits	471	Shared Neighborhood Hits	185
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

DLG4_HUMAN
θ value	4.29542e-18 (rank : 10)	NC score	0.705905 (rank : 19)
Query Neighborhood Hits	290	Target Neighborhood Hits	286	Shared Neighborhood Hits	157
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG4_MOUSE
θ value	4.29542e-18 (rank : 11)	NC score	0.706952 (rank : 18)
Query Neighborhood Hits	290	Target Neighborhood Hits	282	Shared Neighborhood Hits	159
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

LNX1_MOUSE
θ value	9.56915e-18 (rank : 12)	NC score	0.708341 (rank : 17)
Query Neighborhood Hits	290	Target Neighborhood Hits	377	Shared Neighborhood Hits	160
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

DLG2_MOUSE
θ value	1.63225e-17 (rank : 13)	NC score	0.692141 (rank : 27)
Query Neighborhood Hits	290	Target Neighborhood Hits	271	Shared Neighborhood Hits	158
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

LNX2_HUMAN
θ value	1.63225e-17 (rank : 14)	NC score	0.709827 (rank : 16)
Query Neighborhood Hits	290	Target Neighborhood Hits	389	Shared Neighborhood Hits	162
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

MAGI1_MOUSE
θ value	1.63225e-17 (rank : 15)	NC score	0.672367 (rank : 31)
Query Neighborhood Hits	290	Target Neighborhood Hits	403	Shared Neighborhood Hits	186
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

LNX2_MOUSE
θ value	2.7842e-17 (rank : 16)	NC score	0.714775 (rank : 13)
Query Neighborhood Hits	290	Target Neighborhood Hits	407	Shared Neighborhood Hits	160
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

DLG1_MOUSE
θ value	4.74913e-17 (rank : 17)	NC score	0.694767 (rank : 23)
Query Neighborhood Hits	290	Target Neighborhood Hits	285	Shared Neighborhood Hits	154
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

DLG3_MOUSE
θ value	4.74913e-17 (rank : 18)	NC score	0.697462 (rank : 22)
Query Neighborhood Hits	290	Target Neighborhood Hits	274	Shared Neighborhood Hits	157
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

MAGI1_HUMAN
θ value	4.74913e-17 (rank : 19)	NC score	0.666004 (rank : 34)
Query Neighborhood Hits	290	Target Neighborhood Hits	388	Shared Neighborhood Hits	184
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

DLG2_HUMAN
θ value	8.10077e-17 (rank : 20)	NC score	0.690373 (rank : 28)
Query Neighborhood Hits	290	Target Neighborhood Hits	279	Shared Neighborhood Hits	159
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

DLG3_HUMAN
θ value	2.35696e-16 (rank : 21)	NC score	0.693832 (rank : 25)
Query Neighborhood Hits	290	Target Neighborhood Hits	269	Shared Neighborhood Hits	157
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

DLG1_HUMAN
θ value	5.25075e-16 (rank : 22)	NC score	0.692531 (rank : 26)
Query Neighborhood Hits	290	Target Neighborhood Hits	290	Shared Neighborhood Hits	155
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

LNX1_HUMAN
θ value	5.25075e-16 (rank : 23)	NC score	0.702110 (rank : 20)
Query Neighborhood Hits	290	Target Neighborhood Hits	379	Shared Neighborhood Hits	154
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

LAP4_MOUSE
θ value	8.95645e-16 (rank : 24)	NC score	0.477703 (rank : 90)
Query Neighborhood Hits	290	Target Neighborhood Hits	590	Shared Neighborhood Hits	178
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

LAP4_HUMAN
θ value	7.58209e-15 (rank : 25)	NC score	0.479105 (rank : 89)
Query Neighborhood Hits	290	Target Neighborhood Hits	608	Shared Neighborhood Hits	176
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

MAGI2_MOUSE
θ value	2.88119e-14 (rank : 26)	NC score	0.643239 (rank : 42)
Query Neighborhood Hits	290	Target Neighborhood Hits	370	Shared Neighborhood Hits	164
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

MAGI2_HUMAN
θ value	8.38298e-14 (rank : 27)	NC score	0.641784 (rank : 43)
Query Neighborhood Hits	290	Target Neighborhood Hits	373	Shared Neighborhood Hits	164
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

PDZD2_HUMAN
θ value	9.26847e-13 (rank : 28)	NC score	0.690035 (rank : 29)
Query Neighborhood Hits	290	Target Neighborhood Hits	772	Shared Neighborhood Hits	177
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

IL16_HUMAN
θ value	1.133e-10 (rank : 29)	NC score	0.694086 (rank : 24)
Query Neighborhood Hits	290	Target Neighborhood Hits	207	Shared Neighborhood Hits	130
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

NHRF2_HUMAN
θ value	3.29651e-10 (rank : 30)	NC score	0.628647 (rank : 44)
Query Neighborhood Hits	290	Target Neighborhood Hits	197	Shared Neighborhood Hits	150
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

LIN7B_HUMAN
θ value	5.62301e-10 (rank : 31)	NC score	0.717655 (rank : 9)
Query Neighborhood Hits	290	Target Neighborhood Hits	200	Shared Neighborhood Hits	161
SwissProt Accessions	Q9HAP6	Gene names	LIN7B, MALS2, VELI2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein) (hVeli2).

LIN7B_MOUSE
θ value	7.34386e-10 (rank : 32)	NC score	0.717150 (rank : 10)
Query Neighborhood Hits	290	Target Neighborhood Hits	200	Shared Neighborhood Hits	161
SwissProt Accessions	O88951	Gene names	Lin7b, Mals2, Veli2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein).

USH1C_HUMAN
θ value	7.34386e-10 (rank : 33)	NC score	0.697591 (rank : 21)
Query Neighborhood Hits	290	Target Neighborhood Hits	327	Shared Neighborhood Hits	172
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

LIN7C_HUMAN
θ value	1.25267e-09 (rank : 34)	NC score	0.715130 (rank : 11)
Query Neighborhood Hits	290	Target Neighborhood Hits	198	Shared Neighborhood Hits	161
SwissProt Accessions	Q9NUP9	Gene names	LIN7C, MALS3, VELI3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7C_MOUSE
θ value	1.25267e-09 (rank : 35)	NC score	0.715130 (rank : 12)
Query Neighborhood Hits	290	Target Neighborhood Hits	198	Shared Neighborhood Hits	161
SwissProt Accessions	O88952	Gene names	Lin7c, Mals3, Veli3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

NEB2_HUMAN
θ value	1.25267e-09 (rank : 36)	NC score	0.471996 (rank : 91)
Query Neighborhood Hits	290	Target Neighborhood Hits	883	Shared Neighborhood Hits	162
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEB2_MOUSE
θ value	1.25267e-09 (rank : 37)	NC score	0.466623 (rank : 92)
Query Neighborhood Hits	290	Target Neighborhood Hits	889	Shared Neighborhood Hits	162
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

LIN7A_HUMAN
θ value	1.63604e-09 (rank : 38)	NC score	0.711245 (rank : 14)
Query Neighborhood Hits	290	Target Neighborhood Hits	193	Shared Neighborhood Hits	158
SwissProt Accessions	O14910, Q6LES3, Q7LDS4	Gene names	LIN7A, MALS1, VELI1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein) (Tax interaction protein 33) (TIP-33).

LIN7A_MOUSE
θ value	1.63604e-09 (rank : 39)	NC score	0.711216 (rank : 15)
Query Neighborhood Hits	290	Target Neighborhood Hits	193	Shared Neighborhood Hits	158
SwissProt Accessions	Q8JZS0	Gene names	Lin7a, Mals1, Veli1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (mLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein).

NEB1_HUMAN
θ value	1.63604e-09 (rank : 40)	NC score	0.497587 (rank : 82)
Query Neighborhood Hits	290	Target Neighborhood Hits	829	Shared Neighborhood Hits	165
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

PDZD1_MOUSE
θ value	2.79066e-09 (rank : 41)	NC score	0.647602 (rank : 39)
Query Neighborhood Hits	290	Target Neighborhood Hits	191	Shared Neighborhood Hits	141
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

NHRF2_MOUSE
θ value	6.21693e-09 (rank : 42)	NC score	0.617081 (rank : 46)
Query Neighborhood Hits	290	Target Neighborhood Hits	194	Shared Neighborhood Hits	150
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

PDZD1_HUMAN
θ value	6.21693e-09 (rank : 43)	NC score	0.645900 (rank : 41)
Query Neighborhood Hits	290	Target Neighborhood Hits	190	Shared Neighborhood Hits	144
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

GRIP1_HUMAN
θ value	8.11959e-09 (rank : 44)	NC score	0.666861 (rank : 33)
Query Neighborhood Hits	290	Target Neighborhood Hits	231	Shared Neighborhood Hits	168
SwissProt Accessions	Q9Y3R0	Gene names	GRIP1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

PZRN3_HUMAN
θ value	8.11959e-09 (rank : 45)	NC score	0.566275 (rank : 54)
Query Neighborhood Hits	290	Target Neighborhood Hits	461	Shared Neighborhood Hits	154
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_MOUSE
θ value	1.80886e-08 (rank : 46)	NC score	0.570624 (rank : 52)
Query Neighborhood Hits	290	Target Neighborhood Hits	447	Shared Neighborhood Hits	150
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

USH1C_MOUSE
θ value	3.08544e-08 (rank : 47)	NC score	0.647346 (rank : 40)
Query Neighborhood Hits	290	Target Neighborhood Hits	557	Shared Neighborhood Hits	181
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

GRIP1_MOUSE
θ value	4.0297e-08 (rank : 48)	NC score	0.662608 (rank : 35)
Query Neighborhood Hits	290	Target Neighborhood Hits	241	Shared Neighborhood Hits	167
SwissProt Accessions	Q925T6, Q8BLQ3, Q8C0T3, Q925T5, Q925T7	Gene names	Grip1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

DVL2_HUMAN
θ value	6.87365e-08 (rank : 49)	NC score	0.492705 (rank : 84)
Query Neighborhood Hits	290	Target Neighborhood Hits	223	Shared Neighborhood Hits	117
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL2_MOUSE
θ value	6.87365e-08 (rank : 50)	NC score	0.491962 (rank : 85)
Query Neighborhood Hits	290	Target Neighborhood Hits	233	Shared Neighborhood Hits	118
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

NHERF_HUMAN
θ value	8.97725e-08 (rank : 51)	NC score	0.606968 (rank : 47)
Query Neighborhood Hits	290	Target Neighborhood Hits	190	Shared Neighborhood Hits	139
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

AFAD_HUMAN
θ value	1.17247e-07 (rank : 52)	NC score	0.515278 (rank : 69)
Query Neighborhood Hits	290	Target Neighborhood Hits	689	Shared Neighborhood Hits	161
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

K1849_MOUSE
θ value	1.17247e-07 (rank : 53)	NC score	0.543929 (rank : 57)
Query Neighborhood Hits	290	Target Neighborhood Hits	335	Shared Neighborhood Hits	144
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

PZRN4_HUMAN
θ value	1.17247e-07 (rank : 54)	NC score	0.572484 (rank : 51)
Query Neighborhood Hits	290	Target Neighborhood Hits	438	Shared Neighborhood Hits	152
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

DVL3_MOUSE
θ value	1.53129e-07 (rank : 55)	NC score	0.512538 (rank : 71)
Query Neighborhood Hits	290	Target Neighborhood Hits	198	Shared Neighborhood Hits	119
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

DLG5_HUMAN
θ value	1.99992e-07 (rank : 56)	NC score	0.438103 (rank : 98)
Query Neighborhood Hits	290	Target Neighborhood Hits	1088	Shared Neighborhood Hits	190
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

K1849_HUMAN
θ value	1.99992e-07 (rank : 57)	NC score	0.563734 (rank : 55)
Query Neighborhood Hits	290	Target Neighborhood Hits	220	Shared Neighborhood Hits	136
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

NHERF_MOUSE
θ value	1.99992e-07 (rank : 58)	NC score	0.622643 (rank : 45)
Query Neighborhood Hits	290	Target Neighborhood Hits	195	Shared Neighborhood Hits	140
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

WHRN_MOUSE
θ value	1.99992e-07 (rank : 59)	NC score	0.651058 (rank : 38)
Query Neighborhood Hits	290	Target Neighborhood Hits	412	Shared Neighborhood Hits	170
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

GRIP2_HUMAN
θ value	2.61198e-07 (rank : 60)	NC score	0.669741 (rank : 32)
Query Neighborhood Hits	290	Target Neighborhood Hits	256	Shared Neighborhood Hits	165
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

IL16_MOUSE
θ value	2.61198e-07 (rank : 61)	NC score	0.658772 (rank : 36)
Query Neighborhood Hits	290	Target Neighborhood Hits	189	Shared Neighborhood Hits	130
SwissProt Accessions	O54824, O70236, Q3TEM4, Q8R0G5	Gene names	Il16
Domain Architecture	No domain graphic available
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

DVL3_HUMAN
θ value	4.45536e-07 (rank : 62)	NC score	0.510677 (rank : 73)
Query Neighborhood Hits	290	Target Neighborhood Hits	194	Shared Neighborhood Hits	118
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

PDZD3_HUMAN
θ value	4.45536e-07 (rank : 63)	NC score	0.588642 (rank : 49)
Query Neighborhood Hits	290	Target Neighborhood Hits	180	Shared Neighborhood Hits	141
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

PDZD7_HUMAN
θ value	4.45536e-07 (rank : 64)	NC score	0.685771 (rank : 30)
Query Neighborhood Hits	290	Target Neighborhood Hits	181	Shared Neighborhood Hits	149
SwissProt Accessions	Q9H5P4, Q8N321	Gene names	PDZD7, PDZK7
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 7.

SYJ2B_HUMAN
θ value	4.45536e-07 (rank : 65)	NC score	0.761420 (rank : 8)
Query Neighborhood Hits	290	Target Neighborhood Hits	162	Shared Neighborhood Hits	140
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

WHRN_HUMAN
θ value	4.45536e-07 (rank : 66)	NC score	0.655119 (rank : 37)
Query Neighborhood Hits	290	Target Neighborhood Hits	325	Shared Neighborhood Hits	171
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

DVL1_MOUSE
θ value	1.29631e-06 (rank : 67)	NC score	0.505605 (rank : 77)
Query Neighborhood Hits	290	Target Neighborhood Hits	146	Shared Neighborhood Hits	117
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

DVL1_HUMAN
θ value	1.69304e-06 (rank : 68)	NC score	0.507224 (rank : 75)
Query Neighborhood Hits	290	Target Neighborhood Hits	158	Shared Neighborhood Hits	121
SwissProt Accessions	O14640	Gene names	DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

PDZK4_HUMAN
θ value	3.77169e-06 (rank : 69)	NC score	0.485476 (rank : 86)
Query Neighborhood Hits	290	Target Neighborhood Hits	165	Shared Neighborhood Hits	119
SwissProt Accessions	Q76G19, Q8NB75, Q9BUH9, Q9P284	Gene names	PDZK4, KIAA1444, PDZRN4L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

DVL1L_HUMAN
θ value	4.92598e-06 (rank : 70)	NC score	0.493131 (rank : 83)
Query Neighborhood Hits	290	Target Neighborhood Hits	146	Shared Neighborhood Hits	118
SwissProt Accessions	P54792	Gene names	DVL1L1, DVL, DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled- 1-like) (DSH homolog 1-like).

STXB4_HUMAN
θ value	6.43352e-06 (rank : 71)	NC score	0.427970 (rank : 104)
Query Neighborhood Hits	290	Target Neighborhood Hits	616	Shared Neighborhood Hits	128
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

MPP4_HUMAN
θ value	8.40245e-06 (rank : 72)	NC score	0.481343 (rank : 87)
Query Neighborhood Hits	290	Target Neighborhood Hits	205	Shared Neighborhood Hits	133
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

PDZK4_MOUSE
θ value	8.40245e-06 (rank : 73)	NC score	0.480040 (rank : 88)
Query Neighborhood Hits	290	Target Neighborhood Hits	165	Shared Neighborhood Hits	123
SwissProt Accessions	Q9QY39, Q6PHP2	Gene names	Pdzk4, Pdzrn4l, Xlu
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

SNTG2_HUMAN
θ value	8.40245e-06 (rank : 74)	NC score	0.569612 (rank : 53)
Query Neighborhood Hits	290	Target Neighborhood Hits	191	Shared Neighborhood Hits	153
SwissProt Accessions	Q9NY99	Gene names	SNTG2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

SNTA1_MOUSE
θ value	2.44474e-05 (rank : 75)	NC score	0.525537 (rank : 68)
Query Neighborhood Hits	290	Target Neighborhood Hits	170	Shared Neighborhood Hits	139
SwissProt Accessions	Q61234, Q8VEF3	Gene names	Snta1, Snt1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Syntrophin 1).

STXB4_MOUSE
θ value	2.44474e-05 (rank : 76)	NC score	0.427337 (rank : 105)
Query Neighborhood Hits	290	Target Neighborhood Hits	629	Shared Neighborhood Hits	126
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

ARHGB_HUMAN
θ value	5.44631e-05 (rank : 77)	NC score	0.321621 (rank : 124)
Query Neighborhood Hits	290	Target Neighborhood Hits	375	Shared Neighborhood Hits	150
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

SNTA1_HUMAN
θ value	5.44631e-05 (rank : 78)	NC score	0.529616 (rank : 67)
Query Neighborhood Hits	290	Target Neighborhood Hits	186	Shared Neighborhood Hits	142
SwissProt Accessions	Q13424, Q16438	Gene names	SNTA1, SNT1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin 1).

MPP5_HUMAN
θ value	0.000121331 (rank : 79)	NC score	0.437596 (rank : 99)
Query Neighborhood Hits	290	Target Neighborhood Hits	231	Shared Neighborhood Hits	129
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

MPP5_MOUSE
θ value	0.000121331 (rank : 80)	NC score	0.436500 (rank : 100)
Query Neighborhood Hits	290	Target Neighborhood Hits	226	Shared Neighborhood Hits	129
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

RHPN1_MOUSE
θ value	0.000121331 (rank : 81)	NC score	0.335586 (rank : 119)
Query Neighborhood Hits	290	Target Neighborhood Hits	154	Shared Neighborhood Hits	106
SwissProt Accessions	Q61085	Gene names	Rhpn1, Grbp
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

GOPC_MOUSE
θ value	0.000158464 (rank : 82)	NC score	0.589066 (rank : 48)
Query Neighborhood Hits	290	Target Neighborhood Hits	323	Shared Neighborhood Hits	158
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

CSKP_HUMAN
θ value	0.00020696 (rank : 83)	NC score	0.129285 (rank : 176)
Query Neighborhood Hits	290	Target Neighborhood Hits	1022	Shared Neighborhood Hits	122
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

ZO2_MOUSE
θ value	0.00020696 (rank : 84)	NC score	0.505904 (rank : 76)
Query Neighborhood Hits	290	Target Neighborhood Hits	296	Shared Neighborhood Hits	155
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

GOPC_HUMAN
θ value	0.000270298 (rank : 85)	NC score	0.578759 (rank : 50)
Query Neighborhood Hits	290	Target Neighborhood Hits	377	Shared Neighborhood Hits	161
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

NOS1_HUMAN
θ value	0.00035302 (rank : 86)	NC score	0.324859 (rank : 120)
Query Neighborhood Hits	290	Target Neighborhood Hits	218	Shared Neighborhood Hits	134
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

PAR6B_HUMAN
θ value	0.00035302 (rank : 87)	NC score	0.434639 (rank : 102)
Query Neighborhood Hits	290	Target Neighborhood Hits	126	Shared Neighborhood Hits	113
SwissProt Accessions	Q9BYG5, Q9Y510	Gene names	PARD6B, PAR6B
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

PCLO_MOUSE
θ value	0.00035302 (rank : 88)	NC score	0.197668 (rank : 160)
Query Neighborhood Hits	290	Target Neighborhood Hits	2275	Shared Neighborhood Hits	171
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PDZD3_MOUSE
θ value	0.00035302 (rank : 89)	NC score	0.563241 (rank : 56)
Query Neighborhood Hits	290	Target Neighborhood Hits	171	Shared Neighborhood Hits	139
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

ZO2_HUMAN
θ value	0.000461057 (rank : 90)	NC score	0.502893 (rank : 80)
Query Neighborhood Hits	290	Target Neighborhood Hits	289	Shared Neighborhood Hits	155
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

ZO3_MOUSE
θ value	0.000461057 (rank : 91)	NC score	0.543365 (rank : 58)
Query Neighborhood Hits	290	Target Neighborhood Hits	224	Shared Neighborhood Hits	153
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

ARHGC_MOUSE
θ value	0.000602161 (rank : 92)	NC score	0.296875 (rank : 132)
Query Neighborhood Hits	290	Target Neighborhood Hits	344	Shared Neighborhood Hits	145
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

RPTN_MOUSE
θ value	0.000602161 (rank : 93)	NC score	0.054167 (rank : 221)
Query Neighborhood Hits	290	Target Neighborhood Hits	650	Shared Neighborhood Hits	47
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

SNTB2_HUMAN
θ value	0.000602161 (rank : 94)	NC score	0.534537 (rank : 65)
Query Neighborhood Hits	290	Target Neighborhood Hits	180	Shared Neighborhood Hits	140
SwissProt Accessions	Q13425, Q9BY09	Gene names	SNTB2, SNT2B2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

SNTB2_MOUSE
θ value	0.000602161 (rank : 95)	NC score	0.534768 (rank : 64)
Query Neighborhood Hits	290	Target Neighborhood Hits	181	Shared Neighborhood Hits	140
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

SNTG2_MOUSE
θ value	0.000602161 (rank : 96)	NC score	0.531444 (rank : 66)
Query Neighborhood Hits	290	Target Neighborhood Hits	176	Shared Neighborhood Hits	141
SwissProt Accessions	Q925E0	Gene names	Sntg2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

MPP3_HUMAN
θ value	0.000786445 (rank : 97)	NC score	0.435179 (rank : 101)
Query Neighborhood Hits	290	Target Neighborhood Hits	171	Shared Neighborhood Hits	126
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

MPP3_MOUSE
θ value	0.000786445 (rank : 98)	NC score	0.439681 (rank : 97)
Query Neighborhood Hits	290	Target Neighborhood Hits	165	Shared Neighborhood Hits	125
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

PICK1_MOUSE
θ value	0.000786445 (rank : 99)	NC score	0.449615 (rank : 94)
Query Neighborhood Hits	290	Target Neighborhood Hits	131	Shared Neighborhood Hits	119
SwissProt Accessions	Q62083	Gene names	Pick1, Prkcabp
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

SNTB1_HUMAN
θ value	0.000786445 (rank : 100)	NC score	0.505075 (rank : 78)
Query Neighborhood Hits	290	Target Neighborhood Hits	157	Shared Neighborhood Hits	127
SwissProt Accessions	Q13884, O14912, Q4KMG8	Gene names	SNTB1, SNT2B1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Tax interaction protein 43) (TIP-43) (Syntrophin 2) (BSYN2).

SNTB1_MOUSE
θ value	0.000786445 (rank : 101)	NC score	0.503952 (rank : 79)
Query Neighborhood Hits	290	Target Neighborhood Hits	160	Shared Neighborhood Hits	125
SwissProt Accessions	Q99L88, O35925	Gene names	Sntb1, Snt2b1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin 2).

CSKP_MOUSE
θ value	0.00102713 (rank : 102)	NC score	0.125739 (rank : 177)
Query Neighborhood Hits	290	Target Neighborhood Hits	1027	Shared Neighborhood Hits	122
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

MPP4_MOUSE
θ value	0.00102713 (rank : 103)	NC score	0.434445 (rank : 103)
Query Neighborhood Hits	290	Target Neighborhood Hits	188	Shared Neighborhood Hits	118
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

PICK1_HUMAN
θ value	0.00102713 (rank : 104)	NC score	0.448662 (rank : 95)
Query Neighborhood Hits	290	Target Neighborhood Hits	132	Shared Neighborhood Hits	119
SwissProt Accessions	Q9NRD5, O95906	Gene names	PICK1, PRKCABP
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

ARHGC_HUMAN
θ value	0.00134147 (rank : 105)	NC score	0.297108 (rank : 131)
Query Neighborhood Hits	290	Target Neighborhood Hits	351	Shared Neighborhood Hits	142
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

RIMS1_HUMAN
θ value	0.00175202 (rank : 106)	NC score	0.266829 (rank : 139)
Query Neighborhood Hits	290	Target Neighborhood Hits	437	Shared Neighborhood Hits	134
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

NOS1_MOUSE
θ value	0.00228821 (rank : 107)	NC score	0.289059 (rank : 135)
Query Neighborhood Hits	290	Target Neighborhood Hits	155	Shared Neighborhood Hits	108
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

ZO1_HUMAN
θ value	0.00228821 (rank : 108)	NC score	0.502577 (rank : 81)
Query Neighborhood Hits	290	Target Neighborhood Hits	474	Shared Neighborhood Hits	156
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

SNTG1_HUMAN
θ value	0.00298849 (rank : 109)	NC score	0.513869 (rank : 70)
Query Neighborhood Hits	290	Target Neighborhood Hits	181	Shared Neighborhood Hits	150
SwissProt Accessions	Q9NSN8, Q9NY98	Gene names	SNTG1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

APBA3_HUMAN
θ value	0.00390308 (rank : 110)	NC score	0.410489 (rank : 112)
Query Neighborhood Hits	290	Target Neighborhood Hits	201	Shared Neighborhood Hits	133
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

PAR6B_MOUSE
θ value	0.00509761 (rank : 111)	NC score	0.425885 (rank : 107)
Query Neighborhood Hits	290	Target Neighborhood Hits	128	Shared Neighborhood Hits	114
SwissProt Accessions	Q9JK83, Q8R3J8	Gene names	Pard6b, Par6b
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

SNTG1_MOUSE
θ value	0.00509761 (rank : 112)	NC score	0.511942 (rank : 72)
Query Neighborhood Hits	290	Target Neighborhood Hits	179	Shared Neighborhood Hits	149
SwissProt Accessions	Q925E1, Q9D3Z5	Gene names	Sntg1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

LEO1_MOUSE
θ value	0.00665767 (rank : 113)	NC score	0.050766 (rank : 235)
Query Neighborhood Hits	290	Target Neighborhood Hits	946	Shared Neighborhood Hits	65
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

PAR6A_HUMAN
θ value	0.00869519 (rank : 114)	NC score	0.406088 (rank : 113)
Query Neighborhood Hits	290	Target Neighborhood Hits	119	Shared Neighborhood Hits	109
SwissProt Accessions	Q9NPB6, O14911, Q9NPJ7	Gene names	PARD6A, PAR6A
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6) (PAR6C) (Tax interaction protein 40) (TIP-40).

PAR6G_HUMAN
θ value	0.00869519 (rank : 115)	NC score	0.423092 (rank : 109)
Query Neighborhood Hits	290	Target Neighborhood Hits	159	Shared Neighborhood Hits	112
SwissProt Accessions	Q9BYG4	Gene names	PARD6G, PAR6G
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6D).

PAR6G_MOUSE
θ value	0.00869519 (rank : 116)	NC score	0.424522 (rank : 108)
Query Neighborhood Hits	290	Target Neighborhood Hits	121	Shared Neighborhood Hits	111
SwissProt Accessions	Q9JK84	Gene names	Pard6g, Par6g
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6A).

RIMS2_HUMAN
θ value	0.00869519 (rank : 117)	NC score	0.228712 (rank : 151)
Query Neighborhood Hits	290	Target Neighborhood Hits	342	Shared Neighborhood Hits	120
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

RIMS2_MOUSE
θ value	0.00869519 (rank : 118)	NC score	0.227800 (rank : 152)
Query Neighborhood Hits	290	Target Neighborhood Hits	376	Shared Neighborhood Hits	126
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

ZO3_HUMAN
θ value	0.00869519 (rank : 119)	NC score	0.536290 (rank : 62)
Query Neighborhood Hits	290	Target Neighborhood Hits	219	Shared Neighborhood Hits	149
SwissProt Accessions	O95049	Gene names	TJP3, ZO3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

APBA2_HUMAN
θ value	0.0113563 (rank : 120)	NC score	0.414140 (rank : 111)
Query Neighborhood Hits	290	Target Neighborhood Hits	220	Shared Neighborhood Hits	145
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA2_MOUSE
θ value	0.0113563 (rank : 121)	NC score	0.416314 (rank : 110)
Query Neighborhood Hits	290	Target Neighborhood Hits	219	Shared Neighborhood Hits	148
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA1_HUMAN
θ value	0.0148317 (rank : 122)	NC score	0.426574 (rank : 106)
Query Neighborhood Hits	290	Target Neighborhood Hits	325	Shared Neighborhood Hits	150
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

ZO1_MOUSE
θ value	0.0148317 (rank : 123)	NC score	0.509432 (rank : 74)
Query Neighborhood Hits	290	Target Neighborhood Hits	453	Shared Neighborhood Hits	161
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

RPGF2_HUMAN
θ value	0.0193708 (rank : 124)	NC score	0.289356 (rank : 134)
Query Neighborhood Hits	290	Target Neighborhood Hits	242	Shared Neighborhood Hits	131
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

PAR6A_MOUSE
θ value	0.0252991 (rank : 125)	NC score	0.405685 (rank : 114)
Query Neighborhood Hits	290	Target Neighborhood Hits	115	Shared Neighborhood Hits	109
SwissProt Accessions	Q9Z101, Q5RL03, Q6P8R2	Gene names	Pard6a, Par6a
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6).

PDZD6_HUMAN
θ value	0.0252991 (rank : 126)	NC score	0.236192 (rank : 149)
Query Neighborhood Hits	290	Target Neighborhood Hits	81	Shared Neighborhood Hits	56
SwissProt Accessions	Q9ULD6, Q4W5I8, Q86V55	Gene names	PDZD6, KIAA1284, PDZK6
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 6.

RGS12_HUMAN
θ value	0.0252991 (rank : 127)	NC score	0.268924 (rank : 137)
Query Neighborhood Hits	290	Target Neighborhood Hits	333	Shared Neighborhood Hits	120
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

SI1L1_HUMAN
θ value	0.0252991 (rank : 128)	NC score	0.089154 (rank : 189)
Query Neighborhood Hits	290	Target Neighborhood Hits	162	Shared Neighborhood Hits	45
SwissProt Accessions	O43166, O95321, Q9UDU4, Q9UNU4	Gene names	SIPA1L1, E6TP1, KIAA0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1 (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6- targeted protein 1).

MY18A_HUMAN
θ value	0.0330416 (rank : 129)	NC score	0.088646 (rank : 190)
Query Neighborhood Hits	290	Target Neighborhood Hits	1929	Shared Neighborhood Hits	187
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MY18A_MOUSE
θ value	0.0330416 (rank : 130)	NC score	0.094706 (rank : 188)
Query Neighborhood Hits	290	Target Neighborhood Hits	1989	Shared Neighborhood Hits	188
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

APBA3_MOUSE
θ value	0.0431538 (rank : 131)	NC score	0.381351 (rank : 115)
Query Neighborhood Hits	290	Target Neighborhood Hits	174	Shared Neighborhood Hits	126
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

LAP2_HUMAN
θ value	0.0736092 (rank : 132)	NC score	0.214835 (rank : 157)
Query Neighborhood Hits	290	Target Neighborhood Hits	499	Shared Neighborhood Hits	111
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

PRPF3_MOUSE
θ value	0.0736092 (rank : 133)	NC score	0.060874 (rank : 210)
Query Neighborhood Hits	290	Target Neighborhood Hits	74	Shared Neighborhood Hits	7
SwissProt Accessions	Q922U1, Q3TJH4, Q9D6C6	Gene names	Prpf3
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3).

RPGF6_HUMAN
θ value	0.0736092 (rank : 134)	NC score	0.336584 (rank : 118)
Query Neighborhood Hits	290	Target Neighborhood Hits	266	Shared Neighborhood Hits	140
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

EM55_MOUSE
θ value	0.0961366 (rank : 135)	NC score	0.378622 (rank : 117)
Query Neighborhood Hits	290	Target Neighborhood Hits	221	Shared Neighborhood Hits	118
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

GIPC1_MOUSE
θ value	0.0961366 (rank : 136)	NC score	0.248475 (rank : 144)
Query Neighborhood Hits	290	Target Neighborhood Hits	92	Shared Neighborhood Hits	86
SwissProt Accessions	Q9Z0G0	Gene names	Gipc1, Gipc, Rgs19ip1, Semcap1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Synectin) (SemaF cytoplasmic domain-associated protein 1) (SEMCAP-1).

LUZP1_MOUSE
θ value	0.0961366 (rank : 137)	NC score	0.042078 (rank : 252)
Query Neighborhood Hits	290	Target Neighborhood Hits	940	Shared Neighborhood Hits	67
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

PRPF3_HUMAN
θ value	0.0961366 (rank : 138)	NC score	0.060471 (rank : 211)
Query Neighborhood Hits	290	Target Neighborhood Hits	65	Shared Neighborhood Hits	7
SwissProt Accessions	O43395, O43446	Gene names	PRPF3, HPRP3, PRP3
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3) (U4/U6 snRNP 90 kDa protein) (hPrp3).

ELOA1_HUMAN
θ value	0.125558 (rank : 139)	NC score	0.057837 (rank : 214)
Query Neighborhood Hits	290	Target Neighborhood Hits	388	Shared Neighborhood Hits	45
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

EM55_HUMAN
θ value	0.125558 (rank : 140)	NC score	0.379156 (rank : 116)
Query Neighborhood Hits	290	Target Neighborhood Hits	228	Shared Neighborhood Hits	121
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

NIPBL_HUMAN
θ value	0.125558 (rank : 141)	NC score	0.061921 (rank : 208)
Query Neighborhood Hits	290	Target Neighborhood Hits	1311	Shared Neighborhood Hits	87
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

PDLI2_HUMAN
θ value	0.125558 (rank : 142)	NC score	0.317306 (rank : 125)
Query Neighborhood Hits	290	Target Neighborhood Hits	245	Shared Neighborhood Hits	107
SwissProt Accessions	Q96JY6, Q7Z584, Q86WM8, Q8WZ29, Q9H4L9, Q9H7I2	Gene names	PDLIM2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein).

RHPN1_HUMAN
θ value	0.125558 (rank : 143)	NC score	0.295383 (rank : 133)
Query Neighborhood Hits	290	Target Neighborhood Hits	158	Shared Neighborhood Hits	98
SwissProt Accessions	Q8TCX5, Q8TAV1	Gene names	RHPN1
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

GOG8A_HUMAN
θ value	0.163984 (rank : 144)	NC score	0.046817 (rank : 244)
Query Neighborhood Hits	290	Target Neighborhood Hits	635	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NZW0, O94937, Q9NZG8, Q9NZW3	Gene names	GOLGA8A, KIAA0855
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 8A/B (Golgi autoantigen golgin-67) (88 kDa Golgi protein) (Gm88 autoantigen).

PRP40_HUMAN
θ value	0.163984 (rank : 145)	NC score	0.053956 (rank : 223)
Query Neighborhood Hits	290	Target Neighborhood Hits	442	Shared Neighborhood Hits	45
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

PRP40_MOUSE
θ value	0.163984 (rank : 146)	NC score	0.055292 (rank : 220)
Query Neighborhood Hits	290	Target Neighborhood Hits	447	Shared Neighborhood Hits	45
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

SI1L1_MOUSE
θ value	0.163984 (rank : 147)	NC score	0.087620 (rank : 191)
Query Neighborhood Hits	290	Target Neighborhood Hits	189	Shared Neighborhood Hits	50
SwissProt Accessions	Q8C0T5, Q6PDI8, Q80U02, Q8C026	Gene names	Sipa1l1, Kiaa0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1.

GIPC1_HUMAN
θ value	0.21417 (rank : 148)	NC score	0.234427 (rank : 150)
Query Neighborhood Hits	290	Target Neighborhood Hits	91	Shared Neighborhood Hits	81
SwissProt Accessions	O14908, Q9BTC9	Gene names	GIPC1, C19orf3, GIPC, RGS19IP1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Tax interaction protein 2) (TIP-2).

GOGA4_HUMAN
θ value	0.21417 (rank : 149)	NC score	0.041022 (rank : 253)
Query Neighborhood Hits	290	Target Neighborhood Hits	2034	Shared Neighborhood Hits	100
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

MAST1_MOUSE
θ value	0.21417 (rank : 150)	NC score	0.050418 (rank : 236)
Query Neighborhood Hits	290	Target Neighborhood Hits	1123	Shared Neighborhood Hits	118
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

SI1L3_HUMAN
θ value	0.21417 (rank : 151)	NC score	0.073442 (rank : 199)
Query Neighborhood Hits	290	Target Neighborhood Hits	305	Shared Neighborhood Hits	46
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

ZC313_HUMAN
θ value	0.21417 (rank : 152)	NC score	0.070223 (rank : 200)
Query Neighborhood Hits	290	Target Neighborhood Hits	772	Shared Neighborhood Hits	73
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

FYB_MOUSE
θ value	0.279714 (rank : 153)	NC score	0.043804 (rank : 248)
Query Neighborhood Hits	290	Target Neighborhood Hits	194	Shared Neighborhood Hits	16
SwissProt Accessions	O35601, Q9Z2H3	Gene names	Fyb
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

LRRC7_HUMAN
θ value	0.279714 (rank : 154)	NC score	0.222944 (rank : 154)
Query Neighborhood Hits	290	Target Neighborhood Hits	423	Shared Neighborhood Hits	107
SwissProt Accessions	Q96NW7, Q5VXC2, Q5VXC3, Q68D07, Q86VE8, Q8WX20, Q9P2I2	Gene names	LRRC7, KIAA1365, LAP1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

LRRC7_MOUSE
θ value	0.279714 (rank : 155)	NC score	0.222056 (rank : 155)
Query Neighborhood Hits	290	Target Neighborhood Hits	416	Shared Neighborhood Hits	104
SwissProt Accessions	Q80TE7	Gene names	Lrrc7, Kiaa1365, Lap1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

MPP6_MOUSE
θ value	0.279714 (rank : 156)	NC score	0.323521 (rank : 121)
Query Neighborhood Hits	290	Target Neighborhood Hits	187	Shared Neighborhood Hits	91
SwissProt Accessions	Q9JLB0, Q9JLB1, Q9WV37	Gene names	Mpp6, Dlgh4, Pals2
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Protein associated with Lin-7 2) (Dlgh4 protein) (P55T protein).

SHAN2_HUMAN
θ value	0.279714 (rank : 157)	NC score	0.266464 (rank : 141)
Query Neighborhood Hits	290	Target Neighborhood Hits	346	Shared Neighborhood Hits	111
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

SRRM1_MOUSE
θ value	0.279714 (rank : 158)	NC score	0.049695 (rank : 238)
Query Neighborhood Hits	290	Target Neighborhood Hits	966	Shared Neighborhood Hits	59
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

MAST1_HUMAN
θ value	0.365318 (rank : 159)	NC score	0.048539 (rank : 241)
Query Neighborhood Hits	290	Target Neighborhood Hits	1146	Shared Neighborhood Hits	122
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

RHPN2_MOUSE
θ value	0.365318 (rank : 160)	NC score	0.099257 (rank : 187)
Query Neighborhood Hits	290	Target Neighborhood Hits	60	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BWR8, Q9DBN2	Gene names	Rhpn2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2).

RP1L1_MOUSE
θ value	0.365318 (rank : 161)	NC score	0.025144 (rank : 295)
Query Neighborhood Hits	290	Target Neighborhood Hits	170	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CGM2, Q8K0I4	Gene names	Rp1l1, Rp1hl1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein (Retinitis pigmentosa 1-like protein 1).

TRHY_HUMAN
θ value	0.365318 (rank : 162)	NC score	0.049288 (rank : 239)
Query Neighborhood Hits	290	Target Neighborhood Hits	1385	Shared Neighborhood Hits	85
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

EVPL_HUMAN
θ value	0.47712 (rank : 163)	NC score	0.040843 (rank : 254)
Query Neighborhood Hits	290	Target Neighborhood Hits	895	Shared Neighborhood Hits	69
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

LAP2_MOUSE
θ value	0.47712 (rank : 164)	NC score	0.201918 (rank : 158)
Query Neighborhood Hits	290	Target Neighborhood Hits	482	Shared Neighborhood Hits	108
SwissProt Accessions	Q80TH2, Q8BQ14, Q8CE41, Q8K171, Q99JU3, Q9JI47	Gene names	Erbb2ip, Erbin, Kiaa1225, Lap2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

SCG1_HUMAN
θ value	0.47712 (rank : 165)	NC score	0.045679 (rank : 246)
Query Neighborhood Hits	290	Target Neighborhood Hits	156	Shared Neighborhood Hits	20
SwissProt Accessions	P05060, Q9BQV6, Q9UJA6	Gene names	CHGB, SCG1
Domain Architecture
Description	Secretogranin-1 precursor (Secretogranin I) (SgI) (Chromogranin B) (CgB) [Contains: GAWK peptide; CCB peptide].

ATF6B_HUMAN
θ value	0.62314 (rank : 166)	NC score	0.021290 (rank : 302)
Query Neighborhood Hits	290	Target Neighborhood Hits	122	Shared Neighborhood Hits	7
SwissProt Accessions	Q99941, Q13269, Q14343, Q14345, Q99635, Q99637, Q9H3V9, Q9H3W1, Q9NPL0	Gene names	CREBL1, G13
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp) (Protein G13).

GIPC2_HUMAN
θ value	0.62314 (rank : 167)	NC score	0.201557 (rank : 159)
Query Neighborhood Hits	290	Target Neighborhood Hits	93	Shared Neighborhood Hits	88
SwissProt Accessions	Q8TF65, Q8IYD3, Q9NXS7	Gene names	GIPC2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2.

MAST3_HUMAN
θ value	0.62314 (rank : 168)	NC score	0.051200 (rank : 232)
Query Neighborhood Hits	290	Target Neighborhood Hits	1128	Shared Neighborhood Hits	114
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

NC6IP_HUMAN
θ value	0.62314 (rank : 169)	NC score	0.026172 (rank : 292)
Query Neighborhood Hits	290	Target Neighborhood Hits	116	Shared Neighborhood Hits	10
SwissProt Accessions	Q96RS0, Q5GH23, Q8TDG9, Q96QU3, Q9H5V3	Gene names	NCOA6IP, PIMT
Domain Architecture	No domain graphic available
Description	Putative RNA methyltransferase NCOA6IP (EC 2.1.1.-) (Nuclear receptor coactivator 6-interacting protein) (PRIP-interacting protein with methyltransferase motif) (PIPMT) (PIMT) (CLL-associated antigen KW-2) (Hepatocellular carcinoma-associated antigen 137) (HCA137).

BAZ1A_HUMAN
θ value	0.813845 (rank : 170)	NC score	0.034425 (rank : 267)
Query Neighborhood Hits	290	Target Neighborhood Hits	693	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

DNJC3_HUMAN
θ value	0.813845 (rank : 171)	NC score	0.010787 (rank : 324)
Query Neighborhood Hits	290	Target Neighborhood Hits	223	Shared Neighborhood Hits	6
SwissProt Accessions	Q13217, Q86WT9, Q8N4N2	Gene names	DNAJC3, P58IPK, PRKRI
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 3 (Interferon-induced, double-stranded RNA-activated protein kinase inhibitor) (Protein kinase inhibitor p58) (Protein kinase inhibitor of 58 kDa).

LMO7_HUMAN
θ value	0.813845 (rank : 172)	NC score	0.114945 (rank : 184)
Query Neighborhood Hits	290	Target Neighborhood Hits	507	Shared Neighborhood Hits	77
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

MRCKB_MOUSE
θ value	0.813845 (rank : 173)	NC score	0.017442 (rank : 313)
Query Neighborhood Hits	290	Target Neighborhood Hits	2180	Shared Neighborhood Hits	89
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

SYNP2_MOUSE
θ value	0.813845 (rank : 174)	NC score	0.219722 (rank : 156)
Query Neighborhood Hits	290	Target Neighborhood Hits	252	Shared Neighborhood Hits	101
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

ANR12_HUMAN
θ value	1.06291 (rank : 175)	NC score	0.025138 (rank : 296)
Query Neighborhood Hits	290	Target Neighborhood Hits	1081	Shared Neighborhood Hits	65
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

CROP_HUMAN
θ value	1.06291 (rank : 176)	NC score	0.052364 (rank : 230)
Query Neighborhood Hits	290	Target Neighborhood Hits	402	Shared Neighborhood Hits	47
SwissProt Accessions	O95232, Q6PHR9, Q9NUY0, Q9P2S7	Gene names	CROP, CREAP1, O48
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein (cAMP regulatory element-associated protein 1) (CRE-associated protein 1) (CREAP-1) (Luc7A) (Okadaic acid-inducible phosphoprotein OA48-18).

CROP_MOUSE
θ value	1.06291 (rank : 177)	NC score	0.046616 (rank : 245)
Query Neighborhood Hits	290	Target Neighborhood Hits	403	Shared Neighborhood Hits	46
SwissProt Accessions	Q5SUF2, Q3U9D5, Q8BUJ5, Q921Z3, Q9CRS7, Q9CTY4	Gene names	Crop
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein.

CUTL1_MOUSE
θ value	1.06291 (rank : 178)	NC score	0.029320 (rank : 283)
Query Neighborhood Hits	290	Target Neighborhood Hits	1620	Shared Neighborhood Hits	74
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

EFNB3_HUMAN
θ value	1.06291 (rank : 179)	NC score	0.015284 (rank : 318)
Query Neighborhood Hits	290	Target Neighborhood Hits	48	Shared Neighborhood Hits	2
SwissProt Accessions	Q15768, O00680, Q8TBH7, Q92875	Gene names	EFNB3, EPLG8, LERK8
Domain Architecture
Description	Ephrin-B3 precursor (EPH-related receptor tyrosine kinase ligand 8) (LERK-8) (EPH-related receptor transmembrane ligand ELK-L3).

MACF1_HUMAN
θ value	1.06291 (rank : 180)	NC score	0.019976 (rank : 304)
Query Neighborhood Hits	290	Target Neighborhood Hits	1341	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MACF4_HUMAN
θ value	1.06291 (rank : 181)	NC score	0.022946 (rank : 300)
Query Neighborhood Hits	290	Target Neighborhood Hits	1321	Shared Neighborhood Hits	60
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

MPP8_HUMAN
θ value	1.06291 (rank : 182)	NC score	0.033605 (rank : 272)
Query Neighborhood Hits	290	Target Neighborhood Hits	948	Shared Neighborhood Hits	65
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

MRCKB_HUMAN
θ value	1.06291 (rank : 183)	NC score	0.015679 (rank : 317)
Query Neighborhood Hits	290	Target Neighborhood Hits	2239	Shared Neighborhood Hits	93
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

OSBP2_MOUSE
θ value	1.06291 (rank : 184)	NC score	0.010338 (rank : 326)
Query Neighborhood Hits	290	Target Neighborhood Hits	150	Shared Neighborhood Hits	9
SwissProt Accessions	Q5QNQ6, Q8CF21	Gene names	Osbp2
Domain Architecture	No domain graphic available
Description	Oxysterol-binding protein 2.

SDCB1_HUMAN
θ value	1.06291 (rank : 185)	NC score	0.321781 (rank : 123)
Query Neighborhood Hits	290	Target Neighborhood Hits	150	Shared Neighborhood Hits	133
SwissProt Accessions	O00560, O00173, O43391	Gene names	SDCBP, MDA9, SYCL
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Melanoma differentiation- associated protein 9) (MDA-9) (Scaffold protein Pbp1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18).

SDCB1_MOUSE
θ value	1.06291 (rank : 186)	NC score	0.321974 (rank : 122)
Query Neighborhood Hits	290	Target Neighborhood Hits	144	Shared Neighborhood Hits	124
SwissProt Accessions	O08992, Q544P5	Gene names	Sdcbp
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Scaffold protein Pbp1).

SHAN1_HUMAN
θ value	1.06291 (rank : 187)	NC score	0.171121 (rank : 163)
Query Neighborhood Hits	290	Target Neighborhood Hits	1041	Shared Neighborhood Hits	139
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SHAN2_MOUSE
θ value	1.06291 (rank : 188)	NC score	0.237484 (rank : 148)
Query Neighborhood Hits	290	Target Neighborhood Hits	446	Shared Neighborhood Hits	108
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

SIPA1_HUMAN
θ value	1.06291 (rank : 189)	NC score	0.056576 (rank : 216)
Query Neighborhood Hits	290	Target Neighborhood Hits	250	Shared Neighborhood Hits	35
SwissProt Accessions	Q96FS4, O14518, O60484, O60618	Gene names	SIPA1, SPA1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1) (p130 SPA-1).

RBM13_MOUSE
θ value	1.38821 (rank : 190)	NC score	0.036946 (rank : 258)
Query Neighborhood Hits	290	Target Neighborhood Hits	63	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BGS0, Q921E0, Q9D5G6	Gene names	Rbm13
Domain Architecture	No domain graphic available
Description	MAK16-like protein RBM13 (RNA-binding motif protein 13).

SI1L2_MOUSE
θ value	1.38821 (rank : 191)	NC score	0.079984 (rank : 198)
Query Neighborhood Hits	290	Target Neighborhood Hits	124	Shared Neighborhood Hits	46
SwissProt Accessions	Q80TE4, Q6PDY1	Gene names	Sipa1l2, Kiaa0545
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

TX1B3_HUMAN
θ value	1.38821 (rank : 192)	NC score	0.540910 (rank : 60)
Query Neighborhood Hits	290	Target Neighborhood Hits	161	Shared Neighborhood Hits	135
SwissProt Accessions	O14907, Q7LCQ4	Gene names	TAX1BP3, TIP1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1) (Glutaminase-interacting protein 3).

TX1B3_MOUSE
θ value	1.38821 (rank : 193)	NC score	0.535766 (rank : 63)
Query Neighborhood Hits	290	Target Neighborhood Hits	158	Shared Neighborhood Hits	132
SwissProt Accessions	Q9DBG9	Gene names	Tax1bp3
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1).

AXN2_HUMAN
θ value	1.81305 (rank : 194)	NC score	0.038212 (rank : 256)
Query Neighborhood Hits	290	Target Neighborhood Hits	102	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y2T1, Q9H3M6, Q9UH84	Gene names	AXIN2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

CASP_MOUSE
θ value	1.81305 (rank : 195)	NC score	0.027509 (rank : 286)
Query Neighborhood Hits	290	Target Neighborhood Hits	1152	Shared Neighborhood Hits	62
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

K2C5_MOUSE
θ value	1.81305 (rank : 196)	NC score	0.006336 (rank : 334)
Query Neighborhood Hits	290	Target Neighborhood Hits	505	Shared Neighborhood Hits	31
SwissProt Accessions	Q922U2, Q920F2	Gene names	Krt5, Krt2-5
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 5 (Cytokeratin-5) (CK-5) (Keratin-5) (K5).

KIF4A_HUMAN
θ value	1.81305 (rank : 197)	NC score	0.018867 (rank : 306)
Query Neighborhood Hits	290	Target Neighborhood Hits	1159	Shared Neighborhood Hits	67
SwissProt Accessions	O95239, Q86TN3, Q86XX7, Q9NNY6, Q9NY24, Q9UMW3	Gene names	KIF4A, KIF4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

MAP1A_HUMAN
θ value	1.81305 (rank : 198)	NC score	0.037178 (rank : 257)
Query Neighborhood Hits	290	Target Neighborhood Hits	1626	Shared Neighborhood Hits	90
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MAST4_HUMAN
θ value	1.81305 (rank : 199)	NC score	0.051545 (rank : 231)
Query Neighborhood Hits	290	Target Neighborhood Hits	1804	Shared Neighborhood Hits	135
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

PDZD8_HUMAN
θ value	1.81305 (rank : 200)	NC score	0.119653 (rank : 181)
Query Neighborhood Hits	290	Target Neighborhood Hits	185	Shared Neighborhood Hits	44
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

WDR60_MOUSE
θ value	1.81305 (rank : 201)	NC score	0.043586 (rank : 249)
Query Neighborhood Hits	290	Target Neighborhood Hits	344	Shared Neighborhood Hits	45
SwissProt Accessions	Q8C761, Q3UNM4	Gene names	Wdr60
Domain Architecture	No domain graphic available
Description	WD repeat protein 60.

APXL_HUMAN
θ value	2.36792 (rank : 202)	NC score	0.224754 (rank : 153)
Query Neighborhood Hits	290	Target Neighborhood Hits	553	Shared Neighborhood Hits	95
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

BRE1A_MOUSE
θ value	2.36792 (rank : 203)	NC score	0.035357 (rank : 263)
Query Neighborhood Hits	290	Target Neighborhood Hits	1025	Shared Neighborhood Hits	61
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

CCD37_MOUSE
θ value	2.36792 (rank : 204)	NC score	0.034037 (rank : 270)
Query Neighborhood Hits	290	Target Neighborhood Hits	199	Shared Neighborhood Hits	21
SwissProt Accessions	Q80VN0, Q6AXD6	Gene names	Ccdc37
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 37.

CN037_MOUSE
θ value	2.36792 (rank : 205)	NC score	0.035485 (rank : 261)
Query Neighborhood Hits	290	Target Neighborhood Hits	179	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BT18, Q8BFQ7, Q8R1Q5, Q9D6C5	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 homolog precursor.

ETV3_MOUSE
θ value	2.36792 (rank : 206)	NC score	0.009499 (rank : 327)
Query Neighborhood Hits	290	Target Neighborhood Hits	128	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R4Z4, Q9QZW1	Gene names	Etv3, Mets, Pe1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

GIPC2_MOUSE
θ value	2.36792 (rank : 207)	NC score	0.129861 (rank : 175)
Query Neighborhood Hits	290	Target Neighborhood Hits	71	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Z2H7, Q9CVG2	Gene names	Gipc2, Semcap2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2 (SemaF cytoplasmic domain- associated protein 2) (SEMCAP-2).

L2GL1_MOUSE
θ value	2.36792 (rank : 208)	NC score	0.008889 (rank : 329)
Query Neighborhood Hits	290	Target Neighborhood Hits	70	Shared Neighborhood Hits	2
SwissProt Accessions	Q80Y17, Q61856, Q7TNV3, Q8BN92	Gene names	Llgl1, Llglh
Domain Architecture	No domain graphic available
Description	Lethal(2) giant larvae protein homolog 1 (LLGL) (Mlgl) (Mgl-1).

PCNT_MOUSE
θ value	2.36792 (rank : 209)	NC score	0.034382 (rank : 268)
Query Neighborhood Hits	290	Target Neighborhood Hits	1207	Shared Neighborhood Hits	65
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

RNPS1_HUMAN
θ value	2.36792 (rank : 210)	NC score	0.030715 (rank : 278)
Query Neighborhood Hits	290	Target Neighborhood Hits	285	Shared Neighborhood Hits	22
SwissProt Accessions	Q15287, O75308, Q8WY42, Q9NYG3	Gene names	RNPS1, LDC2
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2).

RNPS1_MOUSE
θ value	2.36792 (rank : 211)	NC score	0.030715 (rank : 279)
Query Neighborhood Hits	290	Target Neighborhood Hits	285	Shared Neighborhood Hits	22
SwissProt Accessions	Q99M28, Q3TMJ1, Q922H8	Gene names	Rnps1
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1.

TAD3L_HUMAN
θ value	2.36792 (rank : 212)	NC score	0.035860 (rank : 260)
Query Neighborhood Hits	290	Target Neighborhood Hits	189	Shared Neighborhood Hits	20
SwissProt Accessions	O75528, Q9UFS2	Gene names	TADA3L, ADA3
Domain Architecture	No domain graphic available
Description	Transcriptional adapter 3-like (ADA3-like protein) (ADA3 homolog) (hADA3).

TAD3L_MOUSE
θ value	2.36792 (rank : 213)	NC score	0.036000 (rank : 259)
Query Neighborhood Hits	290	Target Neighborhood Hits	188	Shared Neighborhood Hits	20
SwissProt Accessions	Q8R0L9, Q8CIH4, Q8K289, Q8R5E3, Q9CTJ0	Gene names	Tada3l, Ada3
Domain Architecture	No domain graphic available
Description	Transcriptional adapter 3-like (ADA3-like protein) (ADA3 homolog) (mADA3).

TRIPB_HUMAN
θ value	2.36792 (rank : 214)	NC score	0.029584 (rank : 281)
Query Neighborhood Hits	290	Target Neighborhood Hits	1587	Shared Neighborhood Hits	79
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

CING_MOUSE
θ value	3.0926 (rank : 215)	NC score	0.029409 (rank : 282)
Query Neighborhood Hits	290	Target Neighborhood Hits	1432	Shared Neighborhood Hits	76
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

E41L2_HUMAN
θ value	3.0926 (rank : 216)	NC score	0.038574 (rank : 255)
Query Neighborhood Hits	290	Target Neighborhood Hits	287	Shared Neighborhood Hits	37
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

FGFR3_MOUSE
θ value	3.0926 (rank : 217)	NC score	-0.004839 (rank : 342)
Query Neighborhood Hits	290	Target Neighborhood Hits	1059	Shared Neighborhood Hits	17
SwissProt Accessions	Q61851, Q61564, Q63834	Gene names	Fgfr3, Mfr3, Sam3
Domain Architecture
Description	Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1) (FGFR-3) (Heparin-binding growth factor receptor) (CD333 antigen).

IWS1_MOUSE
θ value	3.0926 (rank : 218)	NC score	0.033830 (rank : 271)
Query Neighborhood Hits	290	Target Neighborhood Hits	1258	Shared Neighborhood Hits	76
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

R3HD1_HUMAN
θ value	3.0926 (rank : 219)	NC score	0.020142 (rank : 303)
Query Neighborhood Hits	290	Target Neighborhood Hits	203	Shared Neighborhood Hits	12
SwissProt Accessions	Q15032, Q8IW32	Gene names	R3HDM1, KIAA0029, R3HDM
Domain Architecture	No domain graphic available
Description	R3H domain-containing protein 1.

RBP22_HUMAN
θ value	3.0926 (rank : 220)	NC score	0.012298 (rank : 323)
Query Neighborhood Hits	290	Target Neighborhood Hits	165	Shared Neighborhood Hits	12
SwissProt Accessions	Q53T03, Q53QN2, Q59GM7	Gene names	RANBP2L2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 2 (RanBP2L2).

SI1L2_HUMAN
θ value	3.0926 (rank : 221)	NC score	0.081755 (rank : 196)
Query Neighborhood Hits	290	Target Neighborhood Hits	131	Shared Neighborhood Hits	45
SwissProt Accessions	Q9P2F8, Q5VXR7, Q5VXR8, Q641Q4, Q8NA38, Q96DZ3, Q9H9F6	Gene names	SIPA1L2, KIAA1389
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

CAF1A_MOUSE
θ value	4.03905 (rank : 222)	NC score	0.034519 (rank : 266)
Query Neighborhood Hits	290	Target Neighborhood Hits	736	Shared Neighborhood Hits	58
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CCD55_MOUSE
θ value	4.03905 (rank : 223)	NC score	0.055883 (rank : 218)
Query Neighborhood Hits	290	Target Neighborhood Hits	519	Shared Neighborhood Hits	61
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

FILA_HUMAN
θ value	4.03905 (rank : 224)	NC score	0.051196 (rank : 233)
Query Neighborhood Hits	290	Target Neighborhood Hits	685	Shared Neighborhood Hits	60
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

NCOR1_HUMAN
θ value	4.03905 (rank : 225)	NC score	0.018665 (rank : 307)
Query Neighborhood Hits	290	Target Neighborhood Hits	577	Shared Neighborhood Hits	41
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

NCOR1_MOUSE
θ value	4.03905 (rank : 226)	NC score	0.026314 (rank : 291)
Query Neighborhood Hits	290	Target Neighborhood Hits	521	Shared Neighborhood Hits	55
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

NKTR_HUMAN
θ value	4.03905 (rank : 227)	NC score	0.027482 (rank : 287)
Query Neighborhood Hits	290	Target Neighborhood Hits	658	Shared Neighborhood Hits	61
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

PREX1_HUMAN
θ value	4.03905 (rank : 228)	NC score	0.044173 (rank : 247)
Query Neighborhood Hits	290	Target Neighborhood Hits	177	Shared Neighborhood Hits	48
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

PSCBP_HUMAN
θ value	4.03905 (rank : 229)	NC score	0.267950 (rank : 138)
Query Neighborhood Hits	290	Target Neighborhood Hits	123	Shared Neighborhood Hits	98
SwissProt Accessions	O60759, Q15630, Q8NE32	Gene names	PSCDBP, CYTIP
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (CYBR) (Cytohesin binder and regulator) (Cytohesin-interacting protein).

RAD50_MOUSE
θ value	4.03905 (rank : 230)	NC score	0.025243 (rank : 294)
Query Neighborhood Hits	290	Target Neighborhood Hits	1366	Shared Neighborhood Hits	76
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

SNPC4_MOUSE
θ value	4.03905 (rank : 231)	NC score	0.018515 (rank : 309)
Query Neighborhood Hits	290	Target Neighborhood Hits	237	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BP86, Q6PGG7, Q80UG9, Q810L1	Gene names	Snapc4
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit).

TPR_HUMAN
θ value	4.03905 (rank : 232)	NC score	0.031242 (rank : 275)
Query Neighborhood Hits	290	Target Neighborhood Hits	1921	Shared Neighborhood Hits	103
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

TRI12_MOUSE
θ value	4.03905 (rank : 233)	NC score	0.022466 (rank : 301)
Query Neighborhood Hits	290	Target Neighborhood Hits	387	Shared Neighborhood Hits	27
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRPM7_MOUSE
θ value	4.03905 (rank : 234)	NC score	0.006296 (rank : 335)
Query Neighborhood Hits	290	Target Neighborhood Hits	113	Shared Neighborhood Hits	8
SwissProt Accessions	Q923J1, Q8C7S7, Q8CE54, Q921Y5, Q925B2, Q9CUT2, Q9JLQ1	Gene names	Trpm7, Chak, Ltrpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1) (Transient receptor potential-phospholipase C- interacting kinase) (TRP-PLIK).

ZN275_HUMAN
θ value	4.03905 (rank : 235)	NC score	-0.008662 (rank : 344)
Query Neighborhood Hits	290	Target Neighborhood Hits	761	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NSD4	Gene names	ZNF275
Domain Architecture	No domain graphic available
Description	Zinc finger protein 275.

ASXL1_HUMAN
θ value	5.27518 (rank : 236)	NC score	0.016527 (rank : 315)
Query Neighborhood Hits	290	Target Neighborhood Hits	260	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IXJ9, Q5JWS9, Q8IYY7, Q9H466, Q9NQF8, Q9UFJ0, Q9UFP8, Q9Y2I4	Gene names	ASXL1, KIAA0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

CCD37_HUMAN
θ value	5.27518 (rank : 237)	NC score	0.025380 (rank : 293)
Query Neighborhood Hits	290	Target Neighborhood Hits	248	Shared Neighborhood Hits	29
SwissProt Accessions	Q494V2, Q494V1, Q494V4, Q8N838	Gene names	CCDC37
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 37.

CF010_HUMAN
θ value	5.27518 (rank : 238)	NC score	0.027022 (rank : 289)
Query Neighborhood Hits	290	Target Neighborhood Hits	329	Shared Neighborhood Hits	36
SwissProt Accessions	Q5SRN2, Q5SPI9, Q5SPJ0, Q5SPK9, Q5SPL0, Q5SRN3, Q5TG25, Q5TG26, Q8N4B6	Gene names	C6orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf10.

CT116_MOUSE
θ value	5.27518 (rank : 239)	NC score	0.034551 (rank : 265)
Query Neighborhood Hits	290	Target Neighborhood Hits	268	Shared Neighborhood Hits	30
SwissProt Accessions	Q80WW9, Q9CT52	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf116 homolog precursor.

GOGA4_MOUSE
θ value	5.27518 (rank : 240)	NC score	0.035367 (rank : 262)
Query Neighborhood Hits	290	Target Neighborhood Hits	1939	Shared Neighborhood Hits	94
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

IDLC_MOUSE
θ value	5.27518 (rank : 241)	NC score	0.034553 (rank : 264)
Query Neighborhood Hits	290	Target Neighborhood Hits	321	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BVN8	Gene names	Dnali1
Domain Architecture	No domain graphic available
Description	Axonemal dynein light intermediate polypeptide 1 (Inner dynein arm light chain, axonemal).

LIMK2_MOUSE
θ value	5.27518 (rank : 242)	NC score	0.019317 (rank : 305)
Query Neighborhood Hits	290	Target Neighborhood Hits	998	Shared Neighborhood Hits	60
SwissProt Accessions	O54785, O54776, O55238, Q9QUL4	Gene names	Limk2
Domain Architecture
Description	LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2).

MPP2_MOUSE
θ value	5.27518 (rank : 243)	NC score	0.314384 (rank : 126)
Query Neighborhood Hits	290	Target Neighborhood Hits	189	Shared Neighborhood Hits	94
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

PTN4_HUMAN
θ value	5.27518 (rank : 244)	NC score	0.135207 (rank : 173)
Query Neighborhood Hits	290	Target Neighborhood Hits	303	Shared Neighborhood Hits	106
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

RM19_HUMAN
θ value	5.27518 (rank : 245)	NC score	0.013246 (rank : 321)
Query Neighborhood Hits	290	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	P49406, Q53TX9	Gene names	MRPL19, KIAA0104
Domain Architecture
Description	39S ribosomal protein L19, mitochondrial precursor (L19mt) (MRP-L19) (MRP-L15).

SYNE2_HUMAN
θ value	5.27518 (rank : 246)	NC score	0.018361 (rank : 311)
Query Neighborhood Hits	290	Target Neighborhood Hits	1323	Shared Neighborhood Hits	60
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

SYP2L_MOUSE
θ value	5.27518 (rank : 247)	NC score	0.172855 (rank : 162)
Query Neighborhood Hits	290	Target Neighborhood Hits	289	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

TCAL5_HUMAN
θ value	5.27518 (rank : 248)	NC score	0.034283 (rank : 269)
Query Neighborhood Hits	290	Target Neighborhood Hits	806	Shared Neighborhood Hits	48
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

TIAM1_HUMAN
θ value	5.27518 (rank : 249)	NC score	0.080699 (rank : 197)
Query Neighborhood Hits	290	Target Neighborhood Hits	225	Shared Neighborhood Hits	69
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

TIAM1_MOUSE
θ value	5.27518 (rank : 250)	NC score	0.055877 (rank : 219)
Query Neighborhood Hits	290	Target Neighborhood Hits	205	Shared Neighborhood Hits	47
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

TR150_HUMAN
θ value	5.27518 (rank : 251)	NC score	0.026521 (rank : 290)
Query Neighborhood Hits	290	Target Neighborhood Hits	313	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y2W1, Q5VTK6	Gene names	THRAP3, TRAP150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

ZKSC1_HUMAN
θ value	5.27518 (rank : 252)	NC score	-0.007910 (rank : 343)
Query Neighborhood Hits	290	Target Neighborhood Hits	949	Shared Neighborhood Hits	29
SwissProt Accessions	P17029, P52745, Q8TBW5, Q8TEK7	Gene names	ZKSCAN1, KOX18, ZNF139, ZNF36
Domain Architecture	No domain graphic available
Description	Zinc finger with KRAB and SCAN domain-containing protein 1 (Zinc finger protein 36) (Zinc finger protein KOX18).

ABCF1_HUMAN
θ value	6.88961 (rank : 253)	NC score	0.018647 (rank : 308)
Query Neighborhood Hits	290	Target Neighborhood Hits	343	Shared Neighborhood Hits	30
SwissProt Accessions	Q8NE71, O14897, Q69YP6	Gene names	ABCF1, ABC50
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50) (TNF-alpha-stimulated ABC protein).

CD2L1_HUMAN
θ value	6.88961 (rank : 254)	NC score	0.007029 (rank : 332)
Query Neighborhood Hits	290	Target Neighborhood Hits	1467	Shared Neighborhood Hits	68
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

CD2L2_HUMAN
θ value	6.88961 (rank : 255)	NC score	0.005536 (rank : 336)
Query Neighborhood Hits	290	Target Neighborhood Hits	1439	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

CROCC_MOUSE
θ value	6.88961 (rank : 256)	NC score	0.030514 (rank : 280)
Query Neighborhood Hits	290	Target Neighborhood Hits	1460	Shared Neighborhood Hits	82
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

DC12_MOUSE
θ value	6.88961 (rank : 257)	NC score	0.013982 (rank : 319)
Query Neighborhood Hits	290	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R1M0	Gene names
Domain Architecture	No domain graphic available
Description	UPF0361 protein DC12 homolog.

DDX3Y_HUMAN
θ value	6.88961 (rank : 258)	NC score	-0.000638 (rank : 341)
Query Neighborhood Hits	290	Target Neighborhood Hits	121	Shared Neighborhood Hits	2
SwissProt Accessions	O15523, Q8IYV7	Gene names	DDX3Y, DBY
Domain Architecture
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal).

ENAH_HUMAN
θ value	6.88961 (rank : 259)	NC score	0.031890 (rank : 274)
Query Neighborhood Hits	290	Target Neighborhood Hits	784	Shared Neighborhood Hits	52
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

FGRL1_HUMAN
θ value	6.88961 (rank : 260)	NC score	0.001563 (rank : 338)
Query Neighborhood Hits	290	Target Neighborhood Hits	335	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N441, Q6PJN1, Q9BXN7, Q9H4D7	Gene names	FGFRL1, FGFR5, FHFR
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5) (FGFR-like protein) (FGF homologous factor receptor).

HOOK3_HUMAN
θ value	6.88961 (rank : 261)	NC score	0.027083 (rank : 288)
Query Neighborhood Hits	290	Target Neighborhood Hits	1070	Shared Neighborhood Hits	64
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

INOC1_HUMAN
θ value	6.88961 (rank : 262)	NC score	0.008289 (rank : 330)
Query Neighborhood Hits	290	Target Neighborhood Hits	181	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ULG1, Q9NTG6	Gene names	INOC1, KIAA1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-) (hINO80).

LAD1_MOUSE
θ value	6.88961 (rank : 263)	NC score	0.017224 (rank : 314)
Query Neighborhood Hits	290	Target Neighborhood Hits	391	Shared Neighborhood Hits	30
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

MLL2_HUMAN
θ value	6.88961 (rank : 264)	NC score	0.016139 (rank : 316)
Query Neighborhood Hits	290	Target Neighborhood Hits	1788	Shared Neighborhood Hits	64
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

NOP14_HUMAN
θ value	6.88961 (rank : 265)	NC score	0.048476 (rank : 242)
Query Neighborhood Hits	290	Target Neighborhood Hits	573	Shared Neighborhood Hits	64
SwissProt Accessions	P78316, Q7LGI5, Q7Z6K0, Q8TBR6	Gene names	NOP14, C4orf9
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

PDLI2_MOUSE
θ value	6.88961 (rank : 266)	NC score	0.266589 (rank : 140)
Query Neighborhood Hits	290	Target Neighborhood Hits	220	Shared Neighborhood Hits	100
SwissProt Accessions	Q8R1G6	Gene names	Pdlim2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique).

RAVR1_MOUSE
θ value	6.88961 (rank : 267)	NC score	0.003393 (rank : 337)
Query Neighborhood Hits	290	Target Neighborhood Hits	179	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CW46, Q5DTT6, Q811K0, Q8C3Z1, Q8CA14	Gene names	Raver1, Kiaa1978
Domain Architecture	No domain graphic available
Description	Ribonucleoprotein PTB-binding 1 (Protein raver-1).

RBCC1_HUMAN
θ value	6.88961 (rank : 268)	NC score	0.028232 (rank : 285)
Query Neighborhood Hits	290	Target Neighborhood Hits	1023	Shared Neighborhood Hits	55
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

TB22A_MOUSE
θ value	6.88961 (rank : 269)	NC score	0.006749 (rank : 333)
Query Neighborhood Hits	290	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R5A6, Q3U268, Q3U3T0, Q8CA49	Gene names	Tbc1d22a, D15Ertd781e
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 22A.

ATRX_MOUSE
θ value	8.99809 (rank : 270)	NC score	0.024247 (rank : 297)
Query Neighborhood Hits	290	Target Neighborhood Hits	682	Shared Neighborhood Hits	63
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

BRE1A_HUMAN
θ value	8.99809 (rank : 271)	NC score	0.032200 (rank : 273)
Query Neighborhood Hits	290	Target Neighborhood Hits	1071	Shared Neighborhood Hits	62
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

CAMLG_HUMAN
θ value	8.99809 (rank : 272)	NC score	0.009459 (rank : 328)
Query Neighborhood Hits	290	Target Neighborhood Hits	15	Shared Neighborhood Hits	5
SwissProt Accessions	P49069	Gene names	CAMLG, CAML
Domain Architecture	No domain graphic available
Description	Calcium signal-modulating cyclophilin ligand (CAML).

CING_HUMAN
θ value	8.99809 (rank : 273)	NC score	0.028237 (rank : 284)
Query Neighborhood Hits	290	Target Neighborhood Hits	1275	Shared Neighborhood Hits	71
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

DC12_HUMAN
θ value	8.99809 (rank : 274)	NC score	0.012680 (rank : 322)
Query Neighborhood Hits	290	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q96FZ2, Q96G34, Q9NRP3	Gene names	C3orf37
Domain Architecture	No domain graphic available
Description	UPF0361 protein DC12.

DREB_MOUSE
θ value	8.99809 (rank : 275)	NC score	0.024206 (rank : 298)
Query Neighborhood Hits	290	Target Neighborhood Hits	446	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QXS6, Q922X1, Q9QXS5	Gene names	Dbn1, Drba
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

EZRI_MOUSE
θ value	8.99809 (rank : 276)	NC score	0.043509 (rank : 250)
Query Neighborhood Hits	290	Target Neighborhood Hits	693	Shared Neighborhood Hits	55
SwissProt Accessions	P26040, Q80ZT8, Q9DCI1	Gene names	Vil2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

FGRL1_MOUSE
θ value	8.99809 (rank : 277)	NC score	0.001162 (rank : 339)
Query Neighborhood Hits	290	Target Neighborhood Hits	325	Shared Neighborhood Hits	5
SwissProt Accessions	Q91V87, Q920C2, Q920C3	Gene names	Fgfrl1, Fgfr5
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5).

FRM4A_HUMAN
θ value	8.99809 (rank : 278)	NC score	0.031206 (rank : 277)
Query Neighborhood Hits	290	Target Neighborhood Hits	110	Shared Neighborhood Hits	12
SwissProt Accessions	Q9P2Q2	Gene names	FRMD4A, FRMD4, KIAA1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

FRM4A_MOUSE
θ value	8.99809 (rank : 279)	NC score	0.031236 (rank : 276)
Query Neighborhood Hits	290	Target Neighborhood Hits	108	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BIE6, Q6PDJ4, Q8CHA6	Gene names	Frmd4a, Frmd4, Kiaa1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

GIPC3_HUMAN
θ value	8.99809 (rank : 280)	NC score	0.123699 (rank : 180)
Query Neighborhood Hits	290	Target Neighborhood Hits	52	Shared Neighborhood Hits	48
SwissProt Accessions	Q8TF64, O75227	Gene names	GIPC3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3.

K0831_HUMAN
θ value	8.99809 (rank : 281)	NC score	0.010506 (rank : 325)
Query Neighborhood Hits	290	Target Neighborhood Hits	203	Shared Neighborhood Hits	20
SwissProt Accessions	Q6ZNE5, O94920	Gene names	KIAA0831
Domain Architecture	No domain graphic available
Description	Protein KIAA0831.

M4K4_HUMAN
θ value	8.99809 (rank : 282)	NC score	0.007920 (rank : 331)
Query Neighborhood Hits	290	Target Neighborhood Hits	1589	Shared Neighborhood Hits	66
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

OBSCN_HUMAN
θ value	8.99809 (rank : 283)	NC score	-0.000465 (rank : 340)
Query Neighborhood Hits	290	Target Neighborhood Hits	1931	Shared Neighborhood Hits	41
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

RBBP6_HUMAN
θ value	8.99809 (rank : 284)	NC score	0.049154 (rank : 240)
Query Neighborhood Hits	290	Target Neighborhood Hits	1135	Shared Neighborhood Hits	80
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RN126_HUMAN
θ value	8.99809 (rank : 285)	NC score	0.018485 (rank : 310)
Query Neighborhood Hits	290	Target Neighborhood Hits	126	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BV68, Q9NWX1	Gene names	RNF126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

RUFY2_HUMAN
θ value	8.99809 (rank : 286)	NC score	0.018219 (rank : 312)
Query Neighborhood Hits	290	Target Neighborhood Hits	1208	Shared Neighborhood Hits	63
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

SFR17_HUMAN
θ value	8.99809 (rank : 287)	NC score	0.047280 (rank : 243)
Query Neighborhood Hits	290	Target Neighborhood Hits	325	Shared Neighborhood Hits	44
SwissProt Accessions	Q8TF01, Q5T064, Q6P2B4, Q6P2N4, Q6PJ93, Q6PK36, Q7Z640, Q8TF00, Q96K10, Q96SM5, Q9P076, Q9P0C0, Q9Y4N3	Gene names	SRRP130, C6orf111
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 130 (Serine-arginine-rich- splicing regulatory protein 130) (SRrp130) (SR-rich protein) (SR- related protein).

SFRS4_MOUSE
θ value	8.99809 (rank : 288)	NC score	0.023933 (rank : 299)
Query Neighborhood Hits	290	Target Neighborhood Hits	406	Shared Neighborhood Hits	41
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

SRRM2_MOUSE
θ value	8.99809 (rank : 289)	NC score	0.043104 (rank : 251)
Query Neighborhood Hits	290	Target Neighborhood Hits	1470	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

ZCPW1_MOUSE
θ value	8.99809 (rank : 290)	NC score	0.013974 (rank : 320)
Query Neighborhood Hits	290	Target Neighborhood Hits	307	Shared Neighborhood Hits	23
SwissProt Accessions	Q6IR42	Gene names	Zcwpw1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1 homolog.

CACB1_HUMAN
θ value	θ > 10 (rank : 291)	NC score	0.053689 (rank : 224)
Query Neighborhood Hits	290	Target Neighborhood Hits	44	Shared Neighborhood Hits	20
SwissProt Accessions	Q02641, O15331, Q02639, Q02640, Q9C085	Gene names	CACNB1, CACNLB1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-1 (CAB1) (Calcium channel voltage-dependent subunit beta 1).

CACB1_MOUSE
θ value	θ > 10 (rank : 292)	NC score	0.056256 (rank : 217)
Query Neighborhood Hits	290	Target Neighborhood Hits	46	Shared Neighborhood Hits	19
SwissProt Accessions	Q8R3Z5, O88517, Q7TPF2, Q8R3Z6, Q9EPT9	Gene names	Cacnb1, Cacnlb1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-1 (CAB1) (Calcium channel voltage-dependent subunit beta 1).

CACB3_HUMAN
θ value	θ > 10 (rank : 293)	NC score	0.053460 (rank : 226)
Query Neighborhood Hits	290	Target Neighborhood Hits	45	Shared Neighborhood Hits	15
SwissProt Accessions	P54284, Q13913	Gene names	CACNB3, CACNLB3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-3 (CAB3) (Calcium channel voltage-dependent subunit beta 3).

CACB3_MOUSE
θ value	θ > 10 (rank : 294)	NC score	0.053299 (rank : 227)
Query Neighborhood Hits	290	Target Neighborhood Hits	48	Shared Neighborhood Hits	17
SwissProt Accessions	P54285	Gene names	Cacnb3, Cacnlb3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-3 (CAB3) (Calcium channel voltage-dependent subunit beta 3) (CCHB3).

CACB4_HUMAN
θ value	θ > 10 (rank : 295)	NC score	0.052661 (rank : 228)
Query Neighborhood Hits	290	Target Neighborhood Hits	47	Shared Neighborhood Hits	17
SwissProt Accessions	O00305, O60515, Q96L40	Gene names	CACNB4, CACNLB4
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-4 (CAB4) (Calcium channel voltage-dependent subunit beta 4).

CACB4_MOUSE
θ value	θ > 10 (rank : 296)	NC score	0.050891 (rank : 234)
Query Neighborhood Hits	290	Target Neighborhood Hits	42	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R0S4, Q8BRN6, Q8CAJ9	Gene names	Cacnb4, Cacnlb4
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-4 (CAB4) (Calcium channel voltage-dependent subunit beta 4).

CAR11_HUMAN
θ value	θ > 10 (rank : 297)	NC score	0.083439 (rank : 195)
Query Neighborhood Hits	290	Target Neighborhood Hits	690	Shared Neighborhood Hits	82
SwissProt Accessions	Q9BXL7, Q548H3	Gene names	CARD11, CARMA1
Domain Architecture
Description	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 3) (Carma 1).

CAR14_HUMAN
θ value	θ > 10 (rank : 298)	NC score	0.060318 (rank : 212)
Query Neighborhood Hits	290	Target Neighborhood Hits	449	Shared Neighborhood Hits	61
SwissProt Accessions	Q9BXL6, Q9BVB5	Gene names	CARD14, CARMA2
Domain Architecture
Description	Caspase recruitment domain-containing protein 14 (CARD-containing MAGUK protein 2) (Carma 2).

CNKR2_HUMAN
θ value	θ > 10 (rank : 299)	NC score	0.104533 (rank : 185)
Query Neighborhood Hits	290	Target Neighborhood Hits	197	Shared Neighborhood Hits	55
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_MOUSE
θ value	θ > 10 (rank : 300)	NC score	0.104515 (rank : 186)
Query Neighborhood Hits	290	Target Neighborhood Hits	197	Shared Neighborhood Hits	54
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CRK_HUMAN
θ value	θ > 10 (rank : 301)	NC score	0.050225 (rank : 237)
Query Neighborhood Hits	290	Target Neighborhood Hits	308	Shared Neighborhood Hits	23
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

GIPC3_MOUSE
θ value	θ > 10 (rank : 302)	NC score	0.117805 (rank : 182)
Query Neighborhood Hits	290	Target Neighborhood Hits	53	Shared Neighborhood Hits	48
SwissProt Accessions	Q8R5M0	Gene names	Gipc3, Rgs19ip3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3 (Regulator of G-protein signaling 19-interacting protein 3).

GRASP_HUMAN
θ value	θ > 10 (rank : 303)	NC score	0.303021 (rank : 129)
Query Neighborhood Hits	290	Target Neighborhood Hits	147	Shared Neighborhood Hits	97
SwissProt Accessions	Q7Z6J2, Q6PIF8, Q7Z741	Gene names	GRASP
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

GRASP_MOUSE
θ value	θ > 10 (rank : 304)	NC score	0.299094 (rank : 130)
Query Neighborhood Hits	290	Target Neighborhood Hits	131	Shared Neighborhood Hits	96
SwissProt Accessions	Q9JJA9, Q9JKL0	Gene names	Grasp
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

HTRA3_HUMAN
θ value	θ > 10 (rank : 305)	NC score	0.062049 (rank : 207)
Query Neighborhood Hits	290	Target Neighborhood Hits	152	Shared Neighborhood Hits	56
SwissProt Accessions	P83110, Q7Z7A2	Gene names	HTRA3, PRSP
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).

HTRA3_MOUSE
θ value	θ > 10 (rank : 306)	NC score	0.068248 (rank : 201)
Query Neighborhood Hits	290	Target Neighborhood Hits	156	Shared Neighborhood Hits	62
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

KGUA_HUMAN
θ value	θ > 10 (rank : 307)	NC score	0.246569 (rank : 146)
Query Neighborhood Hits	290	Target Neighborhood Hits	41	Shared Neighborhood Hits	25
SwissProt Accessions	Q16774	Gene names	GUK1, GMK
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

KGUA_MOUSE
θ value	θ > 10 (rank : 308)	NC score	0.247273 (rank : 145)
Query Neighborhood Hits	290	Target Neighborhood Hits	45	Shared Neighborhood Hits	25
SwissProt Accessions	Q64520	Gene names	Guk1, Gmk
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

LDB3_HUMAN
θ value	θ > 10 (rank : 309)	NC score	0.134987 (rank : 174)
Query Neighborhood Hits	290	Target Neighborhood Hits	497	Shared Neighborhood Hits	92
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

LDB3_MOUSE
θ value	θ > 10 (rank : 310)	NC score	0.136881 (rank : 172)
Query Neighborhood Hits	290	Target Neighborhood Hits	510	Shared Neighborhood Hits	87
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

MPP2_HUMAN
θ value	θ > 10 (rank : 311)	NC score	0.307562 (rank : 128)
Query Neighborhood Hits	290	Target Neighborhood Hits	173	Shared Neighborhood Hits	89
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

MPP6_HUMAN
θ value	θ > 10 (rank : 312)	NC score	0.311917 (rank : 127)
Query Neighborhood Hits	290	Target Neighborhood Hits	180	Shared Neighborhood Hits	88
SwissProt Accessions	Q9NZW5, Q9H0E1	Gene names	MPP6, VAM1
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1).

PDLI1_HUMAN
θ value	θ > 10 (rank : 313)	NC score	0.155413 (rank : 168)
Query Neighborhood Hits	290	Target Neighborhood Hits	242	Shared Neighborhood Hits	77
SwissProt Accessions	O00151, Q5VZH5, Q9BPZ9	Gene names	PDLIM1, CLIM1, CLP36
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

PDLI1_MOUSE
θ value	θ > 10 (rank : 314)	NC score	0.161447 (rank : 166)
Query Neighborhood Hits	290	Target Neighborhood Hits	213	Shared Neighborhood Hits	80
SwissProt Accessions	O70400, Q99K93	Gene names	Pdlim1, Clim1
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

PDLI3_HUMAN
θ value	θ > 10 (rank : 315)	NC score	0.173773 (rank : 161)
Query Neighborhood Hits	290	Target Neighborhood Hits	199	Shared Neighborhood Hits	86
SwissProt Accessions	Q53GG5, O43590, O60439, O60440, Q8N6Y6, Q9BVP4	Gene names	PDLIM3, ALP
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

PDLI3_MOUSE
θ value	θ > 10 (rank : 316)	NC score	0.153214 (rank : 169)
Query Neighborhood Hits	290	Target Neighborhood Hits	197	Shared Neighborhood Hits	82
SwissProt Accessions	O70209	Gene names	Pdlim3
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

PDLI4_HUMAN
θ value	θ > 10 (rank : 317)	NC score	0.167586 (rank : 165)
Query Neighborhood Hits	290	Target Neighborhood Hits	245	Shared Neighborhood Hits	87
SwissProt Accessions	P50479, Q96AT8, Q9BTW8, Q9Y292	Gene names	PDLIM4, RIL
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

PDLI4_MOUSE
θ value	θ > 10 (rank : 318)	NC score	0.167643 (rank : 164)
Query Neighborhood Hits	290	Target Neighborhood Hits	233	Shared Neighborhood Hits	88
SwissProt Accessions	P70271, Q8K0W4	Gene names	Pdlim4, Ril
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

PDLI5_HUMAN
θ value	θ > 10 (rank : 319)	NC score	0.137211 (rank : 171)
Query Neighborhood Hits	290	Target Neighborhood Hits	322	Shared Neighborhood Hits	92
SwissProt Accessions	Q96HC4, O60705	Gene names	PDLIM5, ENH
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

PDLI5_MOUSE
θ value	θ > 10 (rank : 320)	NC score	0.141648 (rank : 170)
Query Neighborhood Hits	290	Target Neighborhood Hits	287	Shared Neighborhood Hits	93
SwissProt Accessions	Q8CI51, Q9QYN0, Q9QYN1, Q9QYN2	Gene names	Pdlim5, Enh
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

PDLI7_HUMAN
θ value	θ > 10 (rank : 321)	NC score	0.123975 (rank : 179)
Query Neighborhood Hits	290	Target Neighborhood Hits	547	Shared Neighborhood Hits	97
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

PDLI7_MOUSE
θ value	θ > 10 (rank : 322)	NC score	0.115581 (rank : 183)
Query Neighborhood Hits	290	Target Neighborhood Hits	279	Shared Neighborhood Hits	80
SwissProt Accessions	Q3TJD7, Q80ZY6, Q810S3, Q8C1S4, Q9CRA1	Gene names	Pdlim7, Enigma
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

PDZ11_HUMAN
θ value	θ > 10 (rank : 323)	NC score	0.542491 (rank : 59)
Query Neighborhood Hits	290	Target Neighborhood Hits	160	Shared Neighborhood Hits	127
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

PDZ11_MOUSE
θ value	θ > 10 (rank : 324)	NC score	0.539376 (rank : 61)
Query Neighborhood Hits	290	Target Neighborhood Hits	154	Shared Neighborhood Hits	120
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

PRAX_HUMAN
θ value	θ > 10 (rank : 325)	NC score	0.064468 (rank : 205)
Query Neighborhood Hits	290	Target Neighborhood Hits	215	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BXM0, Q9BXL9, Q9HCF2	Gene names	PRX, KIAA1620
Domain Architecture
Description	Periaxin.

PRAX_MOUSE
θ value	θ > 10 (rank : 326)	NC score	0.084491 (rank : 194)
Query Neighborhood Hits	290	Target Neighborhood Hits	199	Shared Neighborhood Hits	42
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

PSCBP_MOUSE
θ value	θ > 10 (rank : 327)	NC score	0.283459 (rank : 136)
Query Neighborhood Hits	290	Target Neighborhood Hits	118	Shared Neighborhood Hits	95
SwissProt Accessions	Q91VY6, Q3TZH1, Q8R4T4, Q9QZA9	Gene names	Pscdbp
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (Cbp).

PSMD9_HUMAN
θ value	θ > 10 (rank : 328)	NC score	0.053978 (rank : 222)
Query Neighborhood Hits	290	Target Neighborhood Hits	36	Shared Neighborhood Hits	19
SwissProt Accessions	O00233, Q9BQ42	Gene names	PSMD9
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 9 (26S proteasome regulatory subunit p27).

PTN3_HUMAN
θ value	θ > 10 (rank : 329)	NC score	0.125085 (rank : 178)
Query Neighborhood Hits	290	Target Neighborhood Hits	258	Shared Neighborhood Hits	101
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

RAIN_HUMAN
θ value	θ > 10 (rank : 330)	NC score	0.053491 (rank : 225)
Query Neighborhood Hits	290	Target Neighborhood Hits	33	Shared Neighborhood Hits	3
SwissProt Accessions	Q5U651, Q6U676	Gene names	RASIP1
Domain Architecture	No domain graphic available
Description	Ras-interacting protein 1 (Rain).

RAIN_MOUSE
θ value	θ > 10 (rank : 331)	NC score	0.052521 (rank : 229)
Query Neighborhood Hits	290	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	Q3U0S6, Q6GQW4	Gene names	Rasip1
Domain Architecture	No domain graphic available
Description	Ras-interacting protein 1 (Rain).

RGS3_HUMAN
θ value	θ > 10 (rank : 332)	NC score	0.064731 (rank : 204)
Query Neighborhood Hits	290	Target Neighborhood Hits	1375	Shared Neighborhood Hits	81
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

RGS3_MOUSE
θ value	θ > 10 (rank : 333)	NC score	0.059057 (rank : 213)
Query Neighborhood Hits	290	Target Neighborhood Hits	1621	Shared Neighborhood Hits	92
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

RNF41_HUMAN
θ value	θ > 10 (rank : 334)	NC score	0.084706 (rank : 193)
Query Neighborhood Hits	290	Target Neighborhood Hits	226	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
θ value	θ > 10 (rank : 335)	NC score	0.084836 (rank : 192)
Query Neighborhood Hits	290	Target Neighborhood Hits	224	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

SAV1_HUMAN
θ value	θ > 10 (rank : 336)	NC score	0.066804 (rank : 202)
Query Neighborhood Hits	290	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H4B6, Q6IA58, Q9H949, Q9HAK9	Gene names	SAV1, WW45
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (hWW45).

SAV1_MOUSE
θ value	θ > 10 (rank : 337)	NC score	0.066797 (rank : 203)
Query Neighborhood Hits	290	Target Neighborhood Hits	48	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VEB2, Q9D9N9, Q9ER46	Gene names	Sav1, Ww45, Wwp3
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (mWW45).

SDCB2_HUMAN
θ value	θ > 10 (rank : 338)	NC score	0.256291 (rank : 143)
Query Neighborhood Hits	290	Target Neighborhood Hits	121	Shared Neighborhood Hits	104
SwissProt Accessions	Q9H190, O95892, Q5W0X1, Q9BZ42, Q9H567, Q9NRY8	Gene names	SDCBP2, SITAC18
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

SDCB2_MOUSE
θ value	θ > 10 (rank : 339)	NC score	0.262013 (rank : 142)
Query Neighborhood Hits	290	Target Neighborhood Hits	118	Shared Neighborhood Hits	106
SwissProt Accessions	Q99JZ0	Gene names	Sdcbp2
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

SYNP2_HUMAN
θ value	θ > 10 (rank : 340)	NC score	0.158161 (rank : 167)
Query Neighborhood Hits	290	Target Neighborhood Hits	323	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

SYP2L_HUMAN
θ value	θ > 10 (rank : 341)	NC score	0.240733 (rank : 147)
Query Neighborhood Hits	290	Target Neighborhood Hits	400	Shared Neighborhood Hits	96
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

WWC1_HUMAN
θ value	θ > 10 (rank : 342)	NC score	0.063817 (rank : 206)
Query Neighborhood Hits	290	Target Neighborhood Hits	290	Shared Neighborhood Hits	33
SwissProt Accessions	Q8IX03, O94946, Q6MZX4, Q6Y2F8, Q7Z4G8, Q8WVM4, Q9BT29	Gene names	WWC1, KIAA0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA) (HBeAg-binding protein 3).

WWC1_MOUSE
θ value	θ > 10 (rank : 343)	NC score	0.061562 (rank : 209)
Query Neighborhood Hits	290	Target Neighborhood Hits	290	Shared Neighborhood Hits	26
SwissProt Accessions	Q5SXA9, Q571D0, Q8K1Y3, Q8VD17, Q922W3	Gene names	Wwc1, Kiaa0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA).

YAP1_MOUSE
θ value	θ > 10 (rank : 344)	NC score	0.057142 (rank : 215)
Query Neighborhood Hits	290	Target Neighborhood Hits	96	Shared Neighborhood Hits	12
SwissProt Accessions	P46938, Q52KJ5	Gene names	Yap1, Yap, Yap65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

Hits sorted by NC score

PARD3_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	290	Target Neighborhood Hits	290	Shared Neighborhood Hits	290
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

PARD3_HUMAN
NC score	0.989551 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	290	Target Neighborhood Hits	312	Shared Neighborhood Hits	238
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

PAR3L_HUMAN
NC score	0.936136 (rank : 3)	θ value	5.41814e-138 (rank : 3)
Query Neighborhood Hits	290	Target Neighborhood Hits	297	Shared Neighborhood Hits	154
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

MPDZ_HUMAN
NC score	0.796418 (rank : 4)	θ value	1.5242e-23 (rank : 7)
Query Neighborhood Hits	290	Target Neighborhood Hits	261	Shared Neighborhood Hits	170
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

MPDZ_MOUSE
NC score	0.793894 (rank : 5)	θ value	4.01107e-24 (rank : 4)
Query Neighborhood Hits	290	Target Neighborhood Hits	298	Shared Neighborhood Hits	167
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

INADL_HUMAN
NC score	0.792939 (rank : 6)	θ value	1.5242e-23 (rank : 5)
Query Neighborhood Hits	290	Target Neighborhood Hits	260	Shared Neighborhood Hits	164
SwissProt Accessions	Q8NI35, O15249, O43742, O60833, Q5VUA5, Q5VUA6, Q5VUA7, Q5VUA8, Q5VUA9, Q5VUB0, Q8WU78, Q9H3N9	Gene names	INADL, PATJ
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions).

INADL_MOUSE
NC score	0.791858 (rank : 7)	θ value	1.5242e-23 (rank : 6)
Query Neighborhood Hits	290	Target Neighborhood Hits	290	Shared Neighborhood Hits	170
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

SYJ2B_HUMAN
NC score	0.761420 (rank : 8)	θ value	4.45536e-07 (rank : 65)
Query Neighborhood Hits	290	Target Neighborhood Hits	162	Shared Neighborhood Hits	140
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

LIN7B_HUMAN
NC score	0.717655 (rank : 9)	θ value	5.62301e-10 (rank : 31)
Query Neighborhood Hits	290	Target Neighborhood Hits	200	Shared Neighborhood Hits	161
SwissProt Accessions	Q9HAP6	Gene names	LIN7B, MALS2, VELI2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein) (hVeli2).

LIN7B_MOUSE
NC score	0.717150 (rank : 10)	θ value	7.34386e-10 (rank : 32)
Query Neighborhood Hits	290	Target Neighborhood Hits	200	Shared Neighborhood Hits	161
SwissProt Accessions	O88951	Gene names	Lin7b, Mals2, Veli2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein).

LIN7C_HUMAN
NC score	0.715130 (rank : 11)	θ value	1.25267e-09 (rank : 34)
Query Neighborhood Hits	290	Target Neighborhood Hits	198	Shared Neighborhood Hits	161
SwissProt Accessions	Q9NUP9	Gene names	LIN7C, MALS3, VELI3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7C_MOUSE
NC score	0.715130 (rank : 12)	θ value	1.25267e-09 (rank : 35)
Query Neighborhood Hits	290	Target Neighborhood Hits	198	Shared Neighborhood Hits	161
SwissProt Accessions	O88952	Gene names	Lin7c, Mals3, Veli3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LNX2_MOUSE
NC score	0.714775 (rank : 13)	θ value	2.7842e-17 (rank : 16)
Query Neighborhood Hits	290	Target Neighborhood Hits	407	Shared Neighborhood Hits	160
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

LIN7A_HUMAN
NC score	0.711245 (rank : 14)	θ value	1.63604e-09 (rank : 38)
Query Neighborhood Hits	290	Target Neighborhood Hits	193	Shared Neighborhood Hits	158
SwissProt Accessions	O14910, Q6LES3, Q7LDS4	Gene names	LIN7A, MALS1, VELI1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein) (Tax interaction protein 33) (TIP-33).

LIN7A_MOUSE
NC score	0.711216 (rank : 15)	θ value	1.63604e-09 (rank : 39)
Query Neighborhood Hits	290	Target Neighborhood Hits	193	Shared Neighborhood Hits	158
SwissProt Accessions	Q8JZS0	Gene names	Lin7a, Mals1, Veli1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (mLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein).

LNX2_HUMAN
NC score	0.709827 (rank : 16)	θ value	1.63225e-17 (rank : 14)
Query Neighborhood Hits	290	Target Neighborhood Hits	389	Shared Neighborhood Hits	162
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

LNX1_MOUSE
NC score	0.708341 (rank : 17)	θ value	9.56915e-18 (rank : 12)
Query Neighborhood Hits	290	Target Neighborhood Hits	377	Shared Neighborhood Hits	160
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

DLG4_MOUSE
NC score	0.706952 (rank : 18)	θ value	4.29542e-18 (rank : 11)
Query Neighborhood Hits	290	Target Neighborhood Hits	282	Shared Neighborhood Hits	159
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG4_HUMAN
NC score	0.705905 (rank : 19)	θ value	4.29542e-18 (rank : 10)
Query Neighborhood Hits	290	Target Neighborhood Hits	286	Shared Neighborhood Hits	157
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

LNX1_HUMAN
NC score	0.702110 (rank : 20)	θ value	5.25075e-16 (rank : 23)
Query Neighborhood Hits	290	Target Neighborhood Hits	379	Shared Neighborhood Hits	154
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

USH1C_HUMAN
NC score	0.697591 (rank : 21)	θ value	7.34386e-10 (rank : 33)
Query Neighborhood Hits	290	Target Neighborhood Hits	327	Shared Neighborhood Hits	172
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

DLG3_MOUSE
NC score	0.697462 (rank : 22)	θ value	4.74913e-17 (rank : 18)
Query Neighborhood Hits	290	Target Neighborhood Hits	274	Shared Neighborhood Hits	157
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

DLG1_MOUSE
NC score	0.694767 (rank : 23)	θ value	4.74913e-17 (rank : 17)
Query Neighborhood Hits	290	Target Neighborhood Hits	285	Shared Neighborhood Hits	154
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

IL16_HUMAN
NC score	0.694086 (rank : 24)	θ value	1.133e-10 (rank : 29)
Query Neighborhood Hits	290	Target Neighborhood Hits	207	Shared Neighborhood Hits	130
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

DLG3_HUMAN
NC score	0.693832 (rank : 25)	θ value	2.35696e-16 (rank : 21)
Query Neighborhood Hits	290	Target Neighborhood Hits	269	Shared Neighborhood Hits	157
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

DLG1_HUMAN
NC score	0.692531 (rank : 26)	θ value	5.25075e-16 (rank : 22)
Query Neighborhood Hits	290	Target Neighborhood Hits	290	Shared Neighborhood Hits	155
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

DLG2_MOUSE
NC score	0.692141 (rank : 27)	θ value	1.63225e-17 (rank : 13)
Query Neighborhood Hits	290	Target Neighborhood Hits	271	Shared Neighborhood Hits	158
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

DLG2_HUMAN
NC score	0.690373 (rank : 28)	θ value	8.10077e-17 (rank : 20)
Query Neighborhood Hits	290	Target Neighborhood Hits	279	Shared Neighborhood Hits	159
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

PDZD2_HUMAN
NC score	0.690035 (rank : 29)	θ value	9.26847e-13 (rank : 28)
Query Neighborhood Hits	290	Target Neighborhood Hits	772	Shared Neighborhood Hits	177
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

PDZD7_HUMAN
NC score	0.685771 (rank : 30)	θ value	4.45536e-07 (rank : 64)
Query Neighborhood Hits	290	Target Neighborhood Hits	181	Shared Neighborhood Hits	149
SwissProt Accessions	Q9H5P4, Q8N321	Gene names	PDZD7, PDZK7
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 7.

MAGI1_MOUSE
NC score	0.672367 (rank : 31)	θ value	1.63225e-17 (rank : 15)
Query Neighborhood Hits	290	Target Neighborhood Hits	403	Shared Neighborhood Hits	186
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

GRIP2_HUMAN
NC score	0.669741 (rank : 32)	θ value	2.61198e-07 (rank : 60)
Query Neighborhood Hits	290	Target Neighborhood Hits	256	Shared Neighborhood Hits	165
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

GRIP1_HUMAN
NC score	0.666861 (rank : 33)	θ value	8.11959e-09 (rank : 44)
Query Neighborhood Hits	290	Target Neighborhood Hits	231	Shared Neighborhood Hits	168
SwissProt Accessions	Q9Y3R0	Gene names	GRIP1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

MAGI1_HUMAN
NC score	0.666004 (rank : 34)	θ value	4.74913e-17 (rank : 19)
Query Neighborhood Hits	290	Target Neighborhood Hits	388	Shared Neighborhood Hits	184
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

GRIP1_MOUSE
NC score	0.662608 (rank : 35)	θ value	4.0297e-08 (rank : 48)
Query Neighborhood Hits	290	Target Neighborhood Hits	241	Shared Neighborhood Hits	167
SwissProt Accessions	Q925T6, Q8BLQ3, Q8C0T3, Q925T5, Q925T7	Gene names	Grip1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

IL16_MOUSE
NC score	0.658772 (rank : 36)	θ value	2.61198e-07 (rank : 61)
Query Neighborhood Hits	290	Target Neighborhood Hits	189	Shared Neighborhood Hits	130
SwissProt Accessions	O54824, O70236, Q3TEM4, Q8R0G5	Gene names	Il16
Domain Architecture	No domain graphic available
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

WHRN_HUMAN
NC score	0.655119 (rank : 37)	θ value	4.45536e-07 (rank : 66)
Query Neighborhood Hits	290	Target Neighborhood Hits	325	Shared Neighborhood Hits	171
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

WHRN_MOUSE
NC score	0.651058 (rank : 38)	θ value	1.99992e-07 (rank : 59)
Query Neighborhood Hits	290	Target Neighborhood Hits	412	Shared Neighborhood Hits	170
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

PDZD1_MOUSE
NC score	0.647602 (rank : 39)	θ value	2.79066e-09 (rank : 41)
Query Neighborhood Hits	290	Target Neighborhood Hits	191	Shared Neighborhood Hits	141
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

USH1C_MOUSE
NC score	0.647346 (rank : 40)	θ value	3.08544e-08 (rank : 47)
Query Neighborhood Hits	290	Target Neighborhood Hits	557	Shared Neighborhood Hits	181
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

PDZD1_HUMAN
NC score	0.645900 (rank : 41)	θ value	6.21693e-09 (rank : 43)
Query Neighborhood Hits	290	Target Neighborhood Hits	190	Shared Neighborhood Hits	144
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

MAGI2_MOUSE
NC score	0.643239 (rank : 42)	θ value	2.88119e-14 (rank : 26)
Query Neighborhood Hits	290	Target Neighborhood Hits	370	Shared Neighborhood Hits	164
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

MAGI2_HUMAN
NC score	0.641784 (rank : 43)	θ value	8.38298e-14 (rank : 27)
Query Neighborhood Hits	290	Target Neighborhood Hits	373	Shared Neighborhood Hits	164
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

NHRF2_HUMAN
NC score	0.628647 (rank : 44)	θ value	3.29651e-10 (rank : 30)
Query Neighborhood Hits	290	Target Neighborhood Hits	197	Shared Neighborhood Hits	150
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

NHERF_MOUSE
NC score	0.622643 (rank : 45)	θ value	1.99992e-07 (rank : 58)
Query Neighborhood Hits	290	Target Neighborhood Hits	195	Shared Neighborhood Hits	140
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

NHRF2_MOUSE
NC score	0.617081 (rank : 46)	θ value	6.21693e-09 (rank : 42)
Query Neighborhood Hits	290	Target Neighborhood Hits	194	Shared Neighborhood Hits	150
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

NHERF_HUMAN
NC score	0.606968 (rank : 47)	θ value	8.97725e-08 (rank : 51)
Query Neighborhood Hits	290	Target Neighborhood Hits	190	Shared Neighborhood Hits	139
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

GOPC_MOUSE
NC score	0.589066 (rank : 48)	θ value	0.000158464 (rank : 82)
Query Neighborhood Hits	290	Target Neighborhood Hits	323	Shared Neighborhood Hits	158
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

PDZD3_HUMAN
NC score	0.588642 (rank : 49)	θ value	4.45536e-07 (rank : 63)
Query Neighborhood Hits	290	Target Neighborhood Hits	180	Shared Neighborhood Hits	141
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

GOPC_HUMAN
NC score	0.578759 (rank : 50)	θ value	0.000270298 (rank : 85)
Query Neighborhood Hits	290	Target Neighborhood Hits	377	Shared Neighborhood Hits	161
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

PZRN4_HUMAN
NC score	0.572484 (rank : 51)	θ value	1.17247e-07 (rank : 54)
Query Neighborhood Hits	290	Target Neighborhood Hits	438	Shared Neighborhood Hits	152
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

PZRN3_MOUSE
NC score	0.570624 (rank : 52)	θ value	1.80886e-08 (rank : 46)
Query Neighborhood Hits	290	Target Neighborhood Hits	447	Shared Neighborhood Hits	150
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

SNTG2_HUMAN
NC score	0.569612 (rank : 53)	θ value	8.40245e-06 (rank : 74)
Query Neighborhood Hits	290	Target Neighborhood Hits	191	Shared Neighborhood Hits	153
SwissProt Accessions	Q9NY99	Gene names	SNTG2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

PZRN3_HUMAN
NC score	0.566275 (rank : 54)	θ value	8.11959e-09 (rank : 45)
Query Neighborhood Hits	290	Target Neighborhood Hits	461	Shared Neighborhood Hits	154
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

K1849_HUMAN
NC score	0.563734 (rank : 55)	θ value	1.99992e-07 (rank : 57)
Query Neighborhood Hits	290	Target Neighborhood Hits	220	Shared Neighborhood Hits	136
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

PDZD3_MOUSE
NC score	0.563241 (rank : 56)	θ value	0.00035302 (rank : 89)
Query Neighborhood Hits	290	Target Neighborhood Hits	171	Shared Neighborhood Hits	139
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

K1849_MOUSE
NC score	0.543929 (rank : 57)	θ value	1.17247e-07 (rank : 53)
Query Neighborhood Hits	290	Target Neighborhood Hits	335	Shared Neighborhood Hits	144
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

ZO3_MOUSE
NC score	0.543365 (rank : 58)	θ value	0.000461057 (rank : 91)
Query Neighborhood Hits	290	Target Neighborhood Hits	224	Shared Neighborhood Hits	153
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

PDZ11_HUMAN
NC score	0.542491 (rank : 59)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	290	Target Neighborhood Hits	160	Shared Neighborhood Hits	127
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

TX1B3_HUMAN
NC score	0.540910 (rank : 60)	θ value	1.38821 (rank : 192)
Query Neighborhood Hits	290	Target Neighborhood Hits	161	Shared Neighborhood Hits	135
SwissProt Accessions	O14907, Q7LCQ4	Gene names	TAX1BP3, TIP1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1) (Glutaminase-interacting protein 3).

PDZ11_MOUSE
NC score	0.539376 (rank : 61)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	290	Target Neighborhood Hits	154	Shared Neighborhood Hits	120
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

ZO3_HUMAN
NC score	0.536290 (rank : 62)	θ value	0.00869519 (rank : 119)
Query Neighborhood Hits	290	Target Neighborhood Hits	219	Shared Neighborhood Hits	149
SwissProt Accessions	O95049	Gene names	TJP3, ZO3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

TX1B3_MOUSE
NC score	0.535766 (rank : 63)	θ value	1.38821 (rank : 193)
Query Neighborhood Hits	290	Target Neighborhood Hits	158	Shared Neighborhood Hits	132
SwissProt Accessions	Q9DBG9	Gene names	Tax1bp3
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1).

SNTB2_MOUSE
NC score	0.534768 (rank : 64)	θ value	0.000602161 (rank : 95)
Query Neighborhood Hits	290	Target Neighborhood Hits	181	Shared Neighborhood Hits	140
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

SNTB2_HUMAN
NC score	0.534537 (rank : 65)	θ value	0.000602161 (rank : 94)
Query Neighborhood Hits	290	Target Neighborhood Hits	180	Shared Neighborhood Hits	140
SwissProt Accessions	Q13425, Q9BY09	Gene names	SNTB2, SNT2B2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

SNTG2_MOUSE
NC score	0.531444 (rank : 66)	θ value	0.000602161 (rank : 96)
Query Neighborhood Hits	290	Target Neighborhood Hits	176	Shared Neighborhood Hits	141
SwissProt Accessions	Q925E0	Gene names	Sntg2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

SNTA1_HUMAN
NC score	0.529616 (rank : 67)	θ value	5.44631e-05 (rank : 78)
Query Neighborhood Hits	290	Target Neighborhood Hits	186	Shared Neighborhood Hits	142
SwissProt Accessions	Q13424, Q16438	Gene names	SNTA1, SNT1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin 1).

SNTA1_MOUSE
NC score	0.525537 (rank : 68)	θ value	2.44474e-05 (rank : 75)
Query Neighborhood Hits	290	Target Neighborhood Hits	170	Shared Neighborhood Hits	139
SwissProt Accessions	Q61234, Q8VEF3	Gene names	Snta1, Snt1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Syntrophin 1).

AFAD_HUMAN
NC score	0.515278 (rank : 69)	θ value	1.17247e-07 (rank : 52)
Query Neighborhood Hits	290	Target Neighborhood Hits	689	Shared Neighborhood Hits	161
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

SNTG1_HUMAN
NC score	0.513869 (rank : 70)	θ value	0.00298849 (rank : 109)
Query Neighborhood Hits	290	Target Neighborhood Hits	181	Shared Neighborhood Hits	150
SwissProt Accessions	Q9NSN8, Q9NY98	Gene names	SNTG1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

DVL3_MOUSE
NC score	0.512538 (rank : 71)	θ value	1.53129e-07 (rank : 55)
Query Neighborhood Hits	290	Target Neighborhood Hits	198	Shared Neighborhood Hits	119
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

SNTG1_MOUSE
NC score	0.511942 (rank : 72)	θ value	0.00509761 (rank : 112)
Query Neighborhood Hits	290	Target Neighborhood Hits	179	Shared Neighborhood Hits	149
SwissProt Accessions	Q925E1, Q9D3Z5	Gene names	Sntg1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

DVL3_HUMAN
NC score	0.510677 (rank : 73)	θ value	4.45536e-07 (rank : 62)
Query Neighborhood Hits	290	Target Neighborhood Hits	194	Shared Neighborhood Hits	118
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

ZO1_MOUSE
NC score	0.509432 (rank : 74)	θ value	0.0148317 (rank : 123)
Query Neighborhood Hits	290	Target Neighborhood Hits	453	Shared Neighborhood Hits	161
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

DVL1_HUMAN
NC score	0.507224 (rank : 75)	θ value	1.69304e-06 (rank : 68)
Query Neighborhood Hits	290	Target Neighborhood Hits	158	Shared Neighborhood Hits	121
SwissProt Accessions	O14640	Gene names	DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

ZO2_MOUSE
NC score	0.505904 (rank : 76)	θ value	0.00020696 (rank : 84)
Query Neighborhood Hits	290	Target Neighborhood Hits	296	Shared Neighborhood Hits	155
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

DVL1_MOUSE
NC score	0.505605 (rank : 77)	θ value	1.29631e-06 (rank : 67)
Query Neighborhood Hits	290	Target Neighborhood Hits	146	Shared Neighborhood Hits	117
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

SNTB1_HUMAN
NC score	0.505075 (rank : 78)	θ value	0.000786445 (rank : 100)
Query Neighborhood Hits	290	Target Neighborhood Hits	157	Shared Neighborhood Hits	127
SwissProt Accessions	Q13884, O14912, Q4KMG8	Gene names	SNTB1, SNT2B1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Tax interaction protein 43) (TIP-43) (Syntrophin 2) (BSYN2).

SNTB1_MOUSE
NC score	0.503952 (rank : 79)	θ value	0.000786445 (rank : 101)
Query Neighborhood Hits	290	Target Neighborhood Hits	160	Shared Neighborhood Hits	125
SwissProt Accessions	Q99L88, O35925	Gene names	Sntb1, Snt2b1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin 2).

ZO2_HUMAN
NC score	0.502893 (rank : 80)	θ value	0.000461057 (rank : 90)
Query Neighborhood Hits	290	Target Neighborhood Hits	289	Shared Neighborhood Hits	155
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

ZO1_HUMAN
NC score	0.502577 (rank : 81)	θ value	0.00228821 (rank : 108)
Query Neighborhood Hits	290	Target Neighborhood Hits	474	Shared Neighborhood Hits	156
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

NEB1_HUMAN
NC score	0.497587 (rank : 82)	θ value	1.63604e-09 (rank : 40)
Query Neighborhood Hits	290	Target Neighborhood Hits	829	Shared Neighborhood Hits	165
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

DVL1L_HUMAN
NC score	0.493131 (rank : 83)	θ value	4.92598e-06 (rank : 70)
Query Neighborhood Hits	290	Target Neighborhood Hits	146	Shared Neighborhood Hits	118
SwissProt Accessions	P54792	Gene names	DVL1L1, DVL, DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled- 1-like) (DSH homolog 1-like).

DVL2_HUMAN
NC score	0.492705 (rank : 84)	θ value	6.87365e-08 (rank : 49)
Query Neighborhood Hits	290	Target Neighborhood Hits	223	Shared Neighborhood Hits	117
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL2_MOUSE
NC score	0.491962 (rank : 85)	θ value	6.87365e-08 (rank : 50)
Query Neighborhood Hits	290	Target Neighborhood Hits	233	Shared Neighborhood Hits	118
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

PDZK4_HUMAN
NC score	0.485476 (rank : 86)	θ value	3.77169e-06 (rank : 69)
Query Neighborhood Hits	290	Target Neighborhood Hits	165	Shared Neighborhood Hits	119
SwissProt Accessions	Q76G19, Q8NB75, Q9BUH9, Q9P284	Gene names	PDZK4, KIAA1444, PDZRN4L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

MPP4_HUMAN
NC score	0.481343 (rank : 87)	θ value	8.40245e-06 (rank : 72)
Query Neighborhood Hits	290	Target Neighborhood Hits	205	Shared Neighborhood Hits	133
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

PDZK4_MOUSE
NC score	0.480040 (rank : 88)	θ value	8.40245e-06 (rank : 73)
Query Neighborhood Hits	290	Target Neighborhood Hits	165	Shared Neighborhood Hits	123
SwissProt Accessions	Q9QY39, Q6PHP2	Gene names	Pdzk4, Pdzrn4l, Xlu
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

LAP4_HUMAN
NC score	0.479105 (rank : 89)	θ value	7.58209e-15 (rank : 25)
Query Neighborhood Hits	290	Target Neighborhood Hits	608	Shared Neighborhood Hits	176
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

LAP4_MOUSE
NC score	0.477703 (rank : 90)	θ value	8.95645e-16 (rank : 24)
Query Neighborhood Hits	290	Target Neighborhood Hits	590	Shared Neighborhood Hits	178
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

NEB2_HUMAN
NC score	0.471996 (rank : 91)	θ value	1.25267e-09 (rank : 36)
Query Neighborhood Hits	290	Target Neighborhood Hits	883	Shared Neighborhood Hits	162
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEB2_MOUSE
NC score	0.466623 (rank : 92)	θ value	1.25267e-09 (rank : 37)
Query Neighborhood Hits	290	Target Neighborhood Hits	889	Shared Neighborhood Hits	162
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

PTN13_HUMAN
NC score	0.456150 (rank : 93)	θ value	8.65492e-19 (rank : 9)
Query Neighborhood Hits	290	Target Neighborhood Hits	471	Shared Neighborhood Hits	185
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

PICK1_MOUSE
NC score	0.449615 (rank : 94)	θ value	0.000786445 (rank : 99)
Query Neighborhood Hits	290	Target Neighborhood Hits	131	Shared Neighborhood Hits	119
SwissProt Accessions	Q62083	Gene names	Pick1, Prkcabp
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

PICK1_HUMAN
NC score	0.448662 (rank : 95)	θ value	0.00102713 (rank : 104)
Query Neighborhood Hits	290	Target Neighborhood Hits	132	Shared Neighborhood Hits	119
SwissProt Accessions	Q9NRD5, O95906	Gene names	PICK1, PRKCABP
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

PTN13_MOUSE
NC score	0.442625 (rank : 96)	θ value	3.88503e-19 (rank : 8)
Query Neighborhood Hits	290	Target Neighborhood Hits	426	Shared Neighborhood Hits	171
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

MPP3_MOUSE
NC score	0.439681 (rank : 97)	θ value	0.000786445 (rank : 98)
Query Neighborhood Hits	290	Target Neighborhood Hits	165	Shared Neighborhood Hits	125
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

DLG5_HUMAN
NC score	0.438103 (rank : 98)	θ value	1.99992e-07 (rank : 56)
Query Neighborhood Hits	290	Target Neighborhood Hits	1088	Shared Neighborhood Hits	190
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

MPP5_HUMAN
NC score	0.437596 (rank : 99)	θ value	0.000121331 (rank : 79)
Query Neighborhood Hits	290	Target Neighborhood Hits	231	Shared Neighborhood Hits	129
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

MPP5_MOUSE
NC score	0.436500 (rank : 100)	θ value	0.000121331 (rank : 80)
Query Neighborhood Hits	290	Target Neighborhood Hits	226	Shared Neighborhood Hits	129
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

MPP3_HUMAN
NC score	0.435179 (rank : 101)	θ value	0.000786445 (rank : 97)
Query Neighborhood Hits	290	Target Neighborhood Hits	171	Shared Neighborhood Hits	126
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

PAR6B_HUMAN
NC score	0.434639 (rank : 102)	θ value	0.00035302 (rank : 87)
Query Neighborhood Hits	290	Target Neighborhood Hits	126	Shared Neighborhood Hits	113
SwissProt Accessions	Q9BYG5, Q9Y510	Gene names	PARD6B, PAR6B
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

MPP4_MOUSE
NC score	0.434445 (rank : 103)	θ value	0.00102713 (rank : 103)
Query Neighborhood Hits	290	Target Neighborhood Hits	188	Shared Neighborhood Hits	118
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

STXB4_HUMAN
NC score	0.427970 (rank : 104)	θ value	6.43352e-06 (rank : 71)
Query Neighborhood Hits	290	Target Neighborhood Hits	616	Shared Neighborhood Hits	128
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

STXB4_MOUSE
NC score	0.427337 (rank : 105)	θ value	2.44474e-05 (rank : 76)
Query Neighborhood Hits	290	Target Neighborhood Hits	629	Shared Neighborhood Hits	126
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

APBA1_HUMAN
NC score	0.426574 (rank : 106)	θ value	0.0148317 (rank : 122)
Query Neighborhood Hits	290	Target Neighborhood Hits	325	Shared Neighborhood Hits	150
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

PAR6B_MOUSE
NC score	0.425885 (rank : 107)	θ value	0.00509761 (rank : 111)
Query Neighborhood Hits	290	Target Neighborhood Hits	128	Shared Neighborhood Hits	114
SwissProt Accessions	Q9JK83, Q8R3J8	Gene names	Pard6b, Par6b
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

PAR6G_MOUSE
NC score	0.424522 (rank : 108)	θ value	0.00869519 (rank : 116)
Query Neighborhood Hits	290	Target Neighborhood Hits	121	Shared Neighborhood Hits	111
SwissProt Accessions	Q9JK84	Gene names	Pard6g, Par6g
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6A).

PAR6G_HUMAN
NC score	0.423092 (rank : 109)	θ value	0.00869519 (rank : 115)
Query Neighborhood Hits	290	Target Neighborhood Hits	159	Shared Neighborhood Hits	112
SwissProt Accessions	Q9BYG4	Gene names	PARD6G, PAR6G
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6D).

APBA2_MOUSE
NC score	0.416314 (rank : 110)	θ value	0.0113563 (rank : 121)
Query Neighborhood Hits	290	Target Neighborhood Hits	219	Shared Neighborhood Hits	148
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA2_HUMAN
NC score	0.414140 (rank : 111)	θ value	0.0113563 (rank : 120)
Query Neighborhood Hits	290	Target Neighborhood Hits	220	Shared Neighborhood Hits	145
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA3_HUMAN
NC score	0.410489 (rank : 112)	θ value	0.00390308 (rank : 110)
Query Neighborhood Hits	290	Target Neighborhood Hits	201	Shared Neighborhood Hits	133
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

PAR6A_HUMAN
NC score	0.406088 (rank : 113)	θ value	0.00869519 (rank : 114)
Query Neighborhood Hits	290	Target Neighborhood Hits	119	Shared Neighborhood Hits	109
SwissProt Accessions	Q9NPB6, O14911, Q9NPJ7	Gene names	PARD6A, PAR6A
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6) (PAR6C) (Tax interaction protein 40) (TIP-40).

PAR6A_MOUSE
NC score	0.405685 (rank : 114)	θ value	0.0252991 (rank : 125)
Query Neighborhood Hits	290	Target Neighborhood Hits	115	Shared Neighborhood Hits	109
SwissProt Accessions	Q9Z101, Q5RL03, Q6P8R2	Gene names	Pard6a, Par6a
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6).

APBA3_MOUSE
NC score	0.381351 (rank : 115)	θ value	0.0431538 (rank : 131)
Query Neighborhood Hits	290	Target Neighborhood Hits	174	Shared Neighborhood Hits	126
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

EM55_HUMAN
NC score	0.379156 (rank : 116)	θ value	0.125558 (rank : 140)
Query Neighborhood Hits	290	Target Neighborhood Hits	228	Shared Neighborhood Hits	121
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

EM55_MOUSE
NC score	0.378622 (rank : 117)	θ value	0.0961366 (rank : 135)
Query Neighborhood Hits	290	Target Neighborhood Hits	221	Shared Neighborhood Hits	118
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

RPGF6_HUMAN
NC score	0.336584 (rank : 118)	θ value	0.0736092 (rank : 134)
Query Neighborhood Hits	290	Target Neighborhood Hits	266	Shared Neighborhood Hits	140
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

RHPN1_MOUSE
NC score	0.335586 (rank : 119)	θ value	0.000121331 (rank : 81)
Query Neighborhood Hits	290	Target Neighborhood Hits	154	Shared Neighborhood Hits	106
SwissProt Accessions	Q61085	Gene names	Rhpn1, Grbp
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

NOS1_HUMAN
NC score	0.324859 (rank : 120)	θ value	0.00035302 (rank : 86)
Query Neighborhood Hits	290	Target Neighborhood Hits	218	Shared Neighborhood Hits	134
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

MPP6_MOUSE
NC score	0.323521 (rank : 121)	θ value	0.279714 (rank : 156)
Query Neighborhood Hits	290	Target Neighborhood Hits	187	Shared Neighborhood Hits	91
SwissProt Accessions	Q9JLB0, Q9JLB1, Q9WV37	Gene names	Mpp6, Dlgh4, Pals2
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Protein associated with Lin-7 2) (Dlgh4 protein) (P55T protein).

SDCB1_MOUSE
NC score	0.321974 (rank : 122)	θ value	1.06291 (rank : 186)
Query Neighborhood Hits	290	Target Neighborhood Hits	144	Shared Neighborhood Hits	124
SwissProt Accessions	O08992, Q544P5	Gene names	Sdcbp
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Scaffold protein Pbp1).

SDCB1_HUMAN
NC score	0.321781 (rank : 123)	θ value	1.06291 (rank : 185)
Query Neighborhood Hits	290	Target Neighborhood Hits	150	Shared Neighborhood Hits	133
SwissProt Accessions	O00560, O00173, O43391	Gene names	SDCBP, MDA9, SYCL
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Melanoma differentiation- associated protein 9) (MDA-9) (Scaffold protein Pbp1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18).

ARHGB_HUMAN
NC score	0.321621 (rank : 124)	θ value	5.44631e-05 (rank : 77)
Query Neighborhood Hits	290	Target Neighborhood Hits	375	Shared Neighborhood Hits	150
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

PDLI2_HUMAN
NC score	0.317306 (rank : 125)	θ value	0.125558 (rank : 142)
Query Neighborhood Hits	290	Target Neighborhood Hits	245	Shared Neighborhood Hits	107
SwissProt Accessions	Q96JY6, Q7Z584, Q86WM8, Q8WZ29, Q9H4L9, Q9H7I2	Gene names	PDLIM2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein).

MPP2_MOUSE
NC score	0.314384 (rank : 126)	θ value	5.27518 (rank : 243)
Query Neighborhood Hits	290	Target Neighborhood Hits	189	Shared Neighborhood Hits	94
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

MPP6_HUMAN
NC score	0.311917 (rank : 127)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	290	Target Neighborhood Hits	180	Shared Neighborhood Hits	88
SwissProt Accessions	Q9NZW5, Q9H0E1	Gene names	MPP6, VAM1
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1).

MPP2_HUMAN
NC score	0.307562 (rank : 128)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	290	Target Neighborhood Hits	173	Shared Neighborhood Hits	89
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

GRASP_HUMAN
NC score	0.303021 (rank : 129)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	290	Target Neighborhood Hits	147	Shared Neighborhood Hits	97
SwissProt Accessions	Q7Z6J2, Q6PIF8, Q7Z741	Gene names	GRASP
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

GRASP_MOUSE
NC score	0.299094 (rank : 130)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	290	Target Neighborhood Hits	131	Shared Neighborhood Hits	96
SwissProt Accessions	Q9JJA9, Q9JKL0	Gene names	Grasp
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

ARHGC_HUMAN
NC score	0.297108 (rank : 131)	θ value	0.00134147 (rank : 105)
Query Neighborhood Hits	290	Target Neighborhood Hits	351	Shared Neighborhood Hits	142
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGC_MOUSE
NC score	0.296875 (rank : 132)	θ value	0.000602161 (rank : 92)
Query Neighborhood Hits	290	Target Neighborhood Hits	344	Shared Neighborhood Hits	145
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

RHPN1_HUMAN
NC score	0.295383 (rank : 133)	θ value	0.125558 (rank : 143)
Query Neighborhood Hits	290	Target Neighborhood Hits	158	Shared Neighborhood Hits	98
SwissProt Accessions	Q8TCX5, Q8TAV1	Gene names	RHPN1
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

RPGF2_HUMAN
NC score	0.289356 (rank : 134)	θ value	0.0193708 (rank : 124)
Query Neighborhood Hits	290	Target Neighborhood Hits	242	Shared Neighborhood Hits	131
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

NOS1_MOUSE
NC score	0.289059 (rank : 135)	θ value	0.00228821 (rank : 107)
Query Neighborhood Hits	290	Target Neighborhood Hits	155	Shared Neighborhood Hits	108
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

PSCBP_MOUSE
NC score	0.283459 (rank : 136)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	290	Target Neighborhood Hits	118	Shared Neighborhood Hits	95
SwissProt Accessions	Q91VY6, Q3TZH1, Q8R4T4, Q9QZA9	Gene names	Pscdbp
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (Cbp).

RGS12_HUMAN
NC score	0.268924 (rank : 137)	θ value	0.0252991 (rank : 127)
Query Neighborhood Hits	290	Target Neighborhood Hits	333	Shared Neighborhood Hits	120
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

PSCBP_HUMAN
NC score	0.267950 (rank : 138)	θ value	4.03905 (rank : 229)
Query Neighborhood Hits	290	Target Neighborhood Hits	123	Shared Neighborhood Hits	98
SwissProt Accessions	O60759, Q15630, Q8NE32	Gene names	PSCDBP, CYTIP
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (CYBR) (Cytohesin binder and regulator) (Cytohesin-interacting protein).

RIMS1_HUMAN
NC score	0.266829 (rank : 139)	θ value	0.00175202 (rank : 106)
Query Neighborhood Hits	290	Target Neighborhood Hits	437	Shared Neighborhood Hits	134
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

PDLI2_MOUSE
NC score	0.266589 (rank : 140)	θ value	6.88961 (rank : 266)
Query Neighborhood Hits	290	Target Neighborhood Hits	220	Shared Neighborhood Hits	100
SwissProt Accessions	Q8R1G6	Gene names	Pdlim2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique).

SHAN2_HUMAN
NC score	0.266464 (rank : 141)	θ value	0.279714 (rank : 157)
Query Neighborhood Hits	290	Target Neighborhood Hits	346	Shared Neighborhood Hits	111
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

SDCB2_MOUSE
NC score	0.262013 (rank : 142)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	290	Target Neighborhood Hits	118	Shared Neighborhood Hits	106
SwissProt Accessions	Q99JZ0	Gene names	Sdcbp2
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

SDCB2_HUMAN
NC score	0.256291 (rank : 143)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	290	Target Neighborhood Hits	121	Shared Neighborhood Hits	104
SwissProt Accessions	Q9H190, O95892, Q5W0X1, Q9BZ42, Q9H567, Q9NRY8	Gene names	SDCBP2, SITAC18
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

GIPC1_MOUSE
NC score	0.248475 (rank : 144)	θ value	0.0961366 (rank : 136)
Query Neighborhood Hits	290	Target Neighborhood Hits	92	Shared Neighborhood Hits	86
SwissProt Accessions	Q9Z0G0	Gene names	Gipc1, Gipc, Rgs19ip1, Semcap1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Synectin) (SemaF cytoplasmic domain-associated protein 1) (SEMCAP-1).

KGUA_MOUSE
NC score	0.247273 (rank : 145)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	290	Target Neighborhood Hits	45	Shared Neighborhood Hits	25
SwissProt Accessions	Q64520	Gene names	Guk1, Gmk
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

KGUA_HUMAN
NC score	0.246569 (rank : 146)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	290	Target Neighborhood Hits	41	Shared Neighborhood Hits	25
SwissProt Accessions	Q16774	Gene names	GUK1, GMK
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

SYP2L_HUMAN
NC score	0.240733 (rank : 147)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	290	Target Neighborhood Hits	400	Shared Neighborhood Hits	96
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

SHAN2_MOUSE
NC score	0.237484 (rank : 148)	θ value	1.06291 (rank : 188)
Query Neighborhood Hits	290	Target Neighborhood Hits	446	Shared Neighborhood Hits	108
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

PDZD6_HUMAN
NC score	0.236192 (rank : 149)	θ value	0.0252991 (rank : 126)
Query Neighborhood Hits	290	Target Neighborhood Hits	81	Shared Neighborhood Hits	56
SwissProt Accessions	Q9ULD6, Q4W5I8, Q86V55	Gene names	PDZD6, KIAA1284, PDZK6
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 6.

GIPC1_HUMAN
NC score	0.234427 (rank : 150)	θ value	0.21417 (rank : 148)
Query Neighborhood Hits	290	Target Neighborhood Hits	91	Shared Neighborhood Hits	81
SwissProt Accessions	O14908, Q9BTC9	Gene names	GIPC1, C19orf3, GIPC, RGS19IP1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Tax interaction protein 2) (TIP-2).

RIMS2_HUMAN
NC score	0.228712 (rank : 151)	θ value	0.00869519 (rank : 117)
Query Neighborhood Hits	290	Target Neighborhood Hits	342	Shared Neighborhood Hits	120
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

RIMS2_MOUSE
NC score	0.227800 (rank : 152)	θ value	0.00869519 (rank : 118)
Query Neighborhood Hits	290	Target Neighborhood Hits	376	Shared Neighborhood Hits	126
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

APXL_HUMAN
NC score	0.224754 (rank : 153)	θ value	2.36792 (rank : 202)
Query Neighborhood Hits	290	Target Neighborhood Hits	553	Shared Neighborhood Hits	95
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

LRRC7_HUMAN
NC score	0.222944 (rank : 154)	θ value	0.279714 (rank : 154)
Query Neighborhood Hits	290	Target Neighborhood Hits	423	Shared Neighborhood Hits	107
SwissProt Accessions	Q96NW7, Q5VXC2, Q5VXC3, Q68D07, Q86VE8, Q8WX20, Q9P2I2	Gene names	LRRC7, KIAA1365, LAP1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

LRRC7_MOUSE
NC score	0.222056 (rank : 155)	θ value	0.279714 (rank : 155)
Query Neighborhood Hits	290	Target Neighborhood Hits	416	Shared Neighborhood Hits	104
SwissProt Accessions	Q80TE7	Gene names	Lrrc7, Kiaa1365, Lap1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

SYNP2_MOUSE
NC score	0.219722 (rank : 156)	θ value	0.813845 (rank : 174)
Query Neighborhood Hits	290	Target Neighborhood Hits	252	Shared Neighborhood Hits	101
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

LAP2_HUMAN
NC score	0.214835 (rank : 157)	θ value	0.0736092 (rank : 132)
Query Neighborhood Hits	290	Target Neighborhood Hits	499	Shared Neighborhood Hits	111
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

LAP2_MOUSE
NC score	0.201918 (rank : 158)	θ value	0.47712 (rank : 164)
Query Neighborhood Hits	290	Target Neighborhood Hits	482	Shared Neighborhood Hits	108
SwissProt Accessions	Q80TH2, Q8BQ14, Q8CE41, Q8K171, Q99JU3, Q9JI47	Gene names	Erbb2ip, Erbin, Kiaa1225, Lap2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

GIPC2_HUMAN
NC score	0.201557 (rank : 159)	θ value	0.62314 (rank : 167)
Query Neighborhood Hits	290	Target Neighborhood Hits	93	Shared Neighborhood Hits	88
SwissProt Accessions	Q8TF65, Q8IYD3, Q9NXS7	Gene names	GIPC2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2.

PCLO_MOUSE
NC score	0.197668 (rank : 160)	θ value	0.00035302 (rank : 88)
Query Neighborhood Hits	290	Target Neighborhood Hits	2275	Shared Neighborhood Hits	171
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PDLI3_HUMAN
NC score	0.173773 (rank : 161)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	290	Target Neighborhood Hits	199	Shared Neighborhood Hits	86
SwissProt Accessions	Q53GG5, O43590, O60439, O60440, Q8N6Y6, Q9BVP4	Gene names	PDLIM3, ALP
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

SYP2L_MOUSE
NC score	0.172855 (rank : 162)	θ value	5.27518 (rank : 247)
Query Neighborhood Hits	290	Target Neighborhood Hits	289	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

SHAN1_HUMAN
NC score	0.171121 (rank : 163)	θ value	1.06291 (rank : 187)
Query Neighborhood Hits	290	Target Neighborhood Hits	1041	Shared Neighborhood Hits	139
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

PDLI4_MOUSE
NC score	0.167643 (rank : 164)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	290	Target Neighborhood Hits	233	Shared Neighborhood Hits	88
SwissProt Accessions	P70271, Q8K0W4	Gene names	Pdlim4, Ril
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

PDLI4_HUMAN
NC score	0.167586 (rank : 165)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	290	Target Neighborhood Hits	245	Shared Neighborhood Hits	87
SwissProt Accessions	P50479, Q96AT8, Q9BTW8, Q9Y292	Gene names	PDLIM4, RIL
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

PDLI1_MOUSE
NC score	0.161447 (rank : 166)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	290	Target Neighborhood Hits	213	Shared Neighborhood Hits	80
SwissProt Accessions	O70400, Q99K93	Gene names	Pdlim1, Clim1
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

SYNP2_HUMAN
NC score	0.158161 (rank : 167)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	290	Target Neighborhood Hits	323	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

PDLI1_HUMAN
NC score	0.155413 (rank : 168)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	290	Target Neighborhood Hits	242	Shared Neighborhood Hits	77
SwissProt Accessions	O00151, Q5VZH5, Q9BPZ9	Gene names	PDLIM1, CLIM1, CLP36
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

PDLI3_MOUSE
NC score	0.153214 (rank : 169)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	290	Target Neighborhood Hits	197	Shared Neighborhood Hits	82
SwissProt Accessions	O70209	Gene names	Pdlim3
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

PDLI5_MOUSE
NC score	0.141648 (rank : 170)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	290	Target Neighborhood Hits	287	Shared Neighborhood Hits	93
SwissProt Accessions	Q8CI51, Q9QYN0, Q9QYN1, Q9QYN2	Gene names	Pdlim5, Enh
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

PDLI5_HUMAN
NC score	0.137211 (rank : 171)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	290	Target Neighborhood Hits	322	Shared Neighborhood Hits	92
SwissProt Accessions	Q96HC4, O60705	Gene names	PDLIM5, ENH
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

LDB3_MOUSE
NC score	0.136881 (rank : 172)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	290	Target Neighborhood Hits	510	Shared Neighborhood Hits	87
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

PTN4_HUMAN
NC score	0.135207 (rank : 173)	θ value	5.27518 (rank : 244)
Query Neighborhood Hits	290	Target Neighborhood Hits	303	Shared Neighborhood Hits	106
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

LDB3_HUMAN
NC score	0.134987 (rank : 174)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	290	Target Neighborhood Hits	497	Shared Neighborhood Hits	92
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

GIPC2_MOUSE
NC score	0.129861 (rank : 175)	θ value	2.36792 (rank : 207)
Query Neighborhood Hits	290	Target Neighborhood Hits	71	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Z2H7, Q9CVG2	Gene names	Gipc2, Semcap2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2 (SemaF cytoplasmic domain- associated protein 2) (SEMCAP-2).

CSKP_HUMAN
NC score	0.129285 (rank : 176)	θ value	0.00020696 (rank : 83)
Query Neighborhood Hits	290	Target Neighborhood Hits	1022	Shared Neighborhood Hits	122
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

CSKP_MOUSE
NC score	0.125739 (rank : 177)	θ value	0.00102713 (rank : 102)
Query Neighborhood Hits	290	Target Neighborhood Hits	1027	Shared Neighborhood Hits	122
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

PTN3_HUMAN
NC score	0.125085 (rank : 178)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	290	Target Neighborhood Hits	258	Shared Neighborhood Hits	101
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

PDLI7_HUMAN
NC score	0.123975 (rank : 179)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	290	Target Neighborhood Hits	547	Shared Neighborhood Hits	97
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

GIPC3_HUMAN
NC score	0.123699 (rank : 180)	θ value	8.99809 (rank : 280)
Query Neighborhood Hits	290	Target Neighborhood Hits	52	Shared Neighborhood Hits	48
SwissProt Accessions	Q8TF64, O75227	Gene names	GIPC3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3.

PDZD8_HUMAN
NC score	0.119653 (rank : 181)	θ value	1.81305 (rank : 200)
Query Neighborhood Hits	290	Target Neighborhood Hits	185	Shared Neighborhood Hits	44
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

GIPC3_MOUSE
NC score	0.117805 (rank : 182)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	290	Target Neighborhood Hits	53	Shared Neighborhood Hits	48
SwissProt Accessions	Q8R5M0	Gene names	Gipc3, Rgs19ip3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3 (Regulator of G-protein signaling 19-interacting protein 3).

PDLI7_MOUSE
NC score	0.115581 (rank : 183)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	290	Target Neighborhood Hits	279	Shared Neighborhood Hits	80
SwissProt Accessions	Q3TJD7, Q80ZY6, Q810S3, Q8C1S4, Q9CRA1	Gene names	Pdlim7, Enigma
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

LMO7_HUMAN
NC score	0.114945 (rank : 184)	θ value	0.813845 (rank : 172)
Query Neighborhood Hits	290	Target Neighborhood Hits	507	Shared Neighborhood Hits	77
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

CNKR2_HUMAN
NC score	0.104533 (rank : 185)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	290	Target Neighborhood Hits	197	Shared Neighborhood Hits	55
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_MOUSE
NC score	0.104515 (rank : 186)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	290	Target Neighborhood Hits	197	Shared Neighborhood Hits	54
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

RHPN2_MOUSE
NC score	0.099257 (rank : 187)	θ value	0.365318 (rank : 160)
Query Neighborhood Hits	290	Target Neighborhood Hits	60	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BWR8, Q9DBN2	Gene names	Rhpn2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2).

MY18A_MOUSE
NC score	0.094706 (rank : 188)	θ value	0.0330416 (rank : 130)
Query Neighborhood Hits	290	Target Neighborhood Hits	1989	Shared Neighborhood Hits	188
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

SI1L1_HUMAN
NC score	0.089154 (rank : 189)	θ value	0.0252991 (rank : 128)
Query Neighborhood Hits	290	Target Neighborhood Hits	162	Shared Neighborhood Hits	45
SwissProt Accessions	O43166, O95321, Q9UDU4, Q9UNU4	Gene names	SIPA1L1, E6TP1, KIAA0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1 (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6- targeted protein 1).

MY18A_HUMAN
NC score	0.088646 (rank : 190)	θ value	0.0330416 (rank : 129)
Query Neighborhood Hits	290	Target Neighborhood Hits	1929	Shared Neighborhood Hits	187
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

SI1L1_MOUSE
NC score	0.087620 (rank : 191)	θ value	0.163984 (rank : 147)
Query Neighborhood Hits	290	Target Neighborhood Hits	189	Shared Neighborhood Hits	50
SwissProt Accessions	Q8C0T5, Q6PDI8, Q80U02, Q8C026	Gene names	Sipa1l1, Kiaa0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1.

RNF41_MOUSE
NC score	0.084836 (rank : 192)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	290	Target Neighborhood Hits	224	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_HUMAN
NC score	0.084706 (rank : 193)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	290	Target Neighborhood Hits	226	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

PRAX_MOUSE
NC score	0.084491 (rank : 194)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	290	Target Neighborhood Hits	199	Shared Neighborhood Hits	42
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

CAR11_HUMAN
NC score	0.083439 (rank : 195)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	290	Target Neighborhood Hits	690	Shared Neighborhood Hits	82
SwissProt Accessions	Q9BXL7, Q548H3	Gene names	CARD11, CARMA1
Domain Architecture
Description	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 3) (Carma 1).

SI1L2_HUMAN
NC score	0.081755 (rank : 196)	θ value	3.0926 (rank : 221)
Query Neighborhood Hits	290	Target Neighborhood Hits	131	Shared Neighborhood Hits	45
SwissProt Accessions	Q9P2F8, Q5VXR7, Q5VXR8, Q641Q4, Q8NA38, Q96DZ3, Q9H9F6	Gene names	SIPA1L2, KIAA1389
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

TIAM1_HUMAN
NC score	0.080699 (rank : 197)	θ value	5.27518 (rank : 249)
Query Neighborhood Hits	290	Target Neighborhood Hits	225	Shared Neighborhood Hits	69
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

SI1L2_MOUSE
NC score	0.079984 (rank : 198)	θ value	1.38821 (rank : 191)
Query Neighborhood Hits	290	Target Neighborhood Hits	124	Shared Neighborhood Hits	46
SwissProt Accessions	Q80TE4, Q6PDY1	Gene names	Sipa1l2, Kiaa0545
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

SI1L3_HUMAN
NC score	0.073442 (rank : 199)	θ value	0.21417 (rank : 151)
Query Neighborhood Hits	290	Target Neighborhood Hits	305	Shared Neighborhood Hits	46
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

ZC313_HUMAN
NC score	0.070223 (rank : 200)	θ value	0.21417 (rank : 152)
Query Neighborhood Hits	290	Target Neighborhood Hits	772	Shared Neighborhood Hits	73
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

HTRA3_MOUSE
NC score	0.068248 (rank : 201)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	290	Target Neighborhood Hits	156	Shared Neighborhood Hits	62
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

SAV1_HUMAN
NC score	0.066804 (rank : 202)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	290	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H4B6, Q6IA58, Q9H949, Q9HAK9	Gene names	SAV1, WW45
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (hWW45).

SAV1_MOUSE
NC score	0.066797 (rank : 203)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	290	Target Neighborhood Hits	48	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VEB2, Q9D9N9, Q9ER46	Gene names	Sav1, Ww45, Wwp3
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (mWW45).

RGS3_HUMAN
NC score	0.064731 (rank : 204)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	290	Target Neighborhood Hits	1375	Shared Neighborhood Hits	81
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

PRAX_HUMAN
NC score	0.064468 (rank : 205)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	290	Target Neighborhood Hits	215	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BXM0, Q9BXL9, Q9HCF2	Gene names	PRX, KIAA1620
Domain Architecture
Description	Periaxin.

WWC1_HUMAN
NC score	0.063817 (rank : 206)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	290	Target Neighborhood Hits	290	Shared Neighborhood Hits	33
SwissProt Accessions	Q8IX03, O94946, Q6MZX4, Q6Y2F8, Q7Z4G8, Q8WVM4, Q9BT29	Gene names	WWC1, KIAA0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA) (HBeAg-binding protein 3).

HTRA3_HUMAN
NC score	0.062049 (rank : 207)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	290	Target Neighborhood Hits	152	Shared Neighborhood Hits	56
SwissProt Accessions	P83110, Q7Z7A2	Gene names	HTRA3, PRSP
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).

NIPBL_HUMAN
NC score	0.061921 (rank : 208)	θ value	0.125558 (rank : 141)
Query Neighborhood Hits	290	Target Neighborhood Hits	1311	Shared Neighborhood Hits	87
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

WWC1_MOUSE
NC score	0.061562 (rank : 209)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	290	Target Neighborhood Hits	290	Shared Neighborhood Hits	26
SwissProt Accessions	Q5SXA9, Q571D0, Q8K1Y3, Q8VD17, Q922W3	Gene names	Wwc1, Kiaa0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA).

PRPF3_MOUSE
NC score	0.060874 (rank : 210)	θ value	0.0736092 (rank : 133)
Query Neighborhood Hits	290	Target Neighborhood Hits	74	Shared Neighborhood Hits	7
SwissProt Accessions	Q922U1, Q3TJH4, Q9D6C6	Gene names	Prpf3
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3).

PRPF3_HUMAN
NC score	0.060471 (rank : 211)	θ value	0.0961366 (rank : 138)
Query Neighborhood Hits	290	Target Neighborhood Hits	65	Shared Neighborhood Hits	7
SwissProt Accessions	O43395, O43446	Gene names	PRPF3, HPRP3, PRP3
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3) (U4/U6 snRNP 90 kDa protein) (hPrp3).

CAR14_HUMAN
NC score	0.060318 (rank : 212)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	290	Target Neighborhood Hits	449	Shared Neighborhood Hits	61
SwissProt Accessions	Q9BXL6, Q9BVB5	Gene names	CARD14, CARMA2
Domain Architecture
Description	Caspase recruitment domain-containing protein 14 (CARD-containing MAGUK protein 2) (Carma 2).

RGS3_MOUSE
NC score	0.059057 (rank : 213)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	290	Target Neighborhood Hits	1621	Shared Neighborhood Hits	92
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

ELOA1_HUMAN
NC score	0.057837 (rank : 214)	θ value	0.125558 (rank : 139)
Query Neighborhood Hits	290	Target Neighborhood Hits	388	Shared Neighborhood Hits	45
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

YAP1_MOUSE
NC score	0.057142 (rank : 215)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	290	Target Neighborhood Hits	96	Shared Neighborhood Hits	12
SwissProt Accessions	P46938, Q52KJ5	Gene names	Yap1, Yap, Yap65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

SIPA1_HUMAN
NC score	0.056576 (rank : 216)	θ value	1.06291 (rank : 189)
Query Neighborhood Hits	290	Target Neighborhood Hits	250	Shared Neighborhood Hits	35
SwissProt Accessions	Q96FS4, O14518, O60484, O60618	Gene names	SIPA1, SPA1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1) (p130 SPA-1).

CACB1_MOUSE
NC score	0.056256 (rank : 217)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	290	Target Neighborhood Hits	46	Shared Neighborhood Hits	19
SwissProt Accessions	Q8R3Z5, O88517, Q7TPF2, Q8R3Z6, Q9EPT9	Gene names	Cacnb1, Cacnlb1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-1 (CAB1) (Calcium channel voltage-dependent subunit beta 1).

CCD55_MOUSE
NC score	0.055883 (rank : 218)	θ value	4.03905 (rank : 223)
Query Neighborhood Hits	290	Target Neighborhood Hits	519	Shared Neighborhood Hits	61
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

TIAM1_MOUSE
NC score	0.055877 (rank : 219)	θ value	5.27518 (rank : 250)
Query Neighborhood Hits	290	Target Neighborhood Hits	205	Shared Neighborhood Hits	47
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

PRP40_MOUSE
NC score	0.055292 (rank : 220)	θ value	0.163984 (rank : 146)
Query Neighborhood Hits	290	Target Neighborhood Hits	447	Shared Neighborhood Hits	45
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

RPTN_MOUSE
NC score	0.054167 (rank : 221)	θ value	0.000602161 (rank : 93)
Query Neighborhood Hits	290	Target Neighborhood Hits	650	Shared Neighborhood Hits	47
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

PSMD9_HUMAN
NC score	0.053978 (rank : 222)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	290	Target Neighborhood Hits	36	Shared Neighborhood Hits	19
SwissProt Accessions	O00233, Q9BQ42	Gene names	PSMD9
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 9 (26S proteasome regulatory subunit p27).

PRP40_HUMAN
NC score	0.053956 (rank : 223)	θ value	0.163984 (rank : 145)
Query Neighborhood Hits	290	Target Neighborhood Hits	442	Shared Neighborhood Hits	45
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

CACB1_HUMAN
NC score	0.053689 (rank : 224)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	290	Target Neighborhood Hits	44	Shared Neighborhood Hits	20
SwissProt Accessions	Q02641, O15331, Q02639, Q02640, Q9C085	Gene names	CACNB1, CACNLB1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-1 (CAB1) (Calcium channel voltage-dependent subunit beta 1).

RAIN_HUMAN
NC score	0.053491 (rank : 225)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	290	Target Neighborhood Hits	33	Shared Neighborhood Hits	3
SwissProt Accessions	Q5U651, Q6U676	Gene names	RASIP1
Domain Architecture	No domain graphic available
Description	Ras-interacting protein 1 (Rain).

CACB3_HUMAN
NC score	0.053460 (rank : 226)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	290	Target Neighborhood Hits	45	Shared Neighborhood Hits	15
SwissProt Accessions	P54284, Q13913	Gene names	CACNB3, CACNLB3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-3 (CAB3) (Calcium channel voltage-dependent subunit beta 3).

CACB3_MOUSE
NC score	0.053299 (rank : 227)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	290	Target Neighborhood Hits	48	Shared Neighborhood Hits	17
SwissProt Accessions	P54285	Gene names	Cacnb3, Cacnlb3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-3 (CAB3) (Calcium channel voltage-dependent subunit beta 3) (CCHB3).

CACB4_HUMAN
NC score	0.052661 (rank : 228)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	290	Target Neighborhood Hits	47	Shared Neighborhood Hits	17
SwissProt Accessions	O00305, O60515, Q96L40	Gene names	CACNB4, CACNLB4
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-4 (CAB4) (Calcium channel voltage-dependent subunit beta 4).

RAIN_MOUSE
NC score	0.052521 (rank : 229)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	290	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	Q3U0S6, Q6GQW4	Gene names	Rasip1
Domain Architecture	No domain graphic available
Description	Ras-interacting protein 1 (Rain).

CROP_HUMAN
NC score	0.052364 (rank : 230)	θ value	1.06291 (rank : 176)
Query Neighborhood Hits	290	Target Neighborhood Hits	402	Shared Neighborhood Hits	47
SwissProt Accessions	O95232, Q6PHR9, Q9NUY0, Q9P2S7	Gene names	CROP, CREAP1, O48
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein (cAMP regulatory element-associated protein 1) (CRE-associated protein 1) (CREAP-1) (Luc7A) (Okadaic acid-inducible phosphoprotein OA48-18).

MAST4_HUMAN
NC score	0.051545 (rank : 231)	θ value	1.81305 (rank : 199)
Query Neighborhood Hits	290	Target Neighborhood Hits	1804	Shared Neighborhood Hits	135
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

MAST3_HUMAN
NC score	0.051200 (rank : 232)	θ value	0.62314 (rank : 168)
Query Neighborhood Hits	290	Target Neighborhood Hits	1128	Shared Neighborhood Hits	114
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

FILA_HUMAN
NC score	0.051196 (rank : 233)	θ value	4.03905 (rank : 224)
Query Neighborhood Hits	290	Target Neighborhood Hits	685	Shared Neighborhood Hits	60
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

CACB4_MOUSE
NC score	0.050891 (rank : 234)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	290	Target Neighborhood Hits	42	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R0S4, Q8BRN6, Q8CAJ9	Gene names	Cacnb4, Cacnlb4
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-4 (CAB4) (Calcium channel voltage-dependent subunit beta 4).

LEO1_MOUSE
NC score	0.050766 (rank : 235)	θ value	0.00665767 (rank : 113)
Query Neighborhood Hits	290	Target Neighborhood Hits	946	Shared Neighborhood Hits	65
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

MAST1_MOUSE
NC score	0.050418 (rank : 236)	θ value	0.21417 (rank : 150)
Query Neighborhood Hits	290	Target Neighborhood Hits	1123	Shared Neighborhood Hits	118
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

CRK_HUMAN
NC score	0.050225 (rank : 237)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	290	Target Neighborhood Hits	308	Shared Neighborhood Hits	23
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

SRRM1_MOUSE
NC score	0.049695 (rank : 238)	θ value	0.279714 (rank : 158)
Query Neighborhood Hits	290	Target Neighborhood Hits	966	Shared Neighborhood Hits	59
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

TRHY_HUMAN
NC score	0.049288 (rank : 239)	θ value	0.365318 (rank : 162)
Query Neighborhood Hits	290	Target Neighborhood Hits	1385	Shared Neighborhood Hits	85
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

RBBP6_HUMAN
NC score	0.049154 (rank : 240)	θ value	8.99809 (rank : 284)
Query Neighborhood Hits	290	Target Neighborhood Hits	1135	Shared Neighborhood Hits	80
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

MAST1_HUMAN
NC score	0.048539 (rank : 241)	θ value	0.365318 (rank : 159)
Query Neighborhood Hits	290	Target Neighborhood Hits	1146	Shared Neighborhood Hits	122
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

NOP14_HUMAN
NC score	0.048476 (rank : 242)	θ value	6.88961 (rank : 265)
Query Neighborhood Hits	290	Target Neighborhood Hits	573	Shared Neighborhood Hits	64
SwissProt Accessions	P78316, Q7LGI5, Q7Z6K0, Q8TBR6	Gene names	NOP14, C4orf9
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

SFR17_HUMAN
NC score	0.047280 (rank : 243)	θ value	8.99809 (rank : 287)
Query Neighborhood Hits	290	Target Neighborhood Hits	325	Shared Neighborhood Hits	44
SwissProt Accessions	Q8TF01, Q5T064, Q6P2B4, Q6P2N4, Q6PJ93, Q6PK36, Q7Z640, Q8TF00, Q96K10, Q96SM5, Q9P076, Q9P0C0, Q9Y4N3	Gene names	SRRP130, C6orf111
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 130 (Serine-arginine-rich- splicing regulatory protein 130) (SRrp130) (SR-rich protein) (SR- related protein).

GOG8A_HUMAN
NC score	0.046817 (rank : 244)	θ value	0.163984 (rank : 144)
Query Neighborhood Hits	290	Target Neighborhood Hits	635	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NZW0, O94937, Q9NZG8, Q9NZW3	Gene names	GOLGA8A, KIAA0855
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 8A/B (Golgi autoantigen golgin-67) (88 kDa Golgi protein) (Gm88 autoantigen).

CROP_MOUSE
NC score	0.046616 (rank : 245)	θ value	1.06291 (rank : 177)
Query Neighborhood Hits	290	Target Neighborhood Hits	403	Shared Neighborhood Hits	46
SwissProt Accessions	Q5SUF2, Q3U9D5, Q8BUJ5, Q921Z3, Q9CRS7, Q9CTY4	Gene names	Crop
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein.

SCG1_HUMAN
NC score	0.045679 (rank : 246)	θ value	0.47712 (rank : 165)
Query Neighborhood Hits	290	Target Neighborhood Hits	156	Shared Neighborhood Hits	20
SwissProt Accessions	P05060, Q9BQV6, Q9UJA6	Gene names	CHGB, SCG1
Domain Architecture
Description	Secretogranin-1 precursor (Secretogranin I) (SgI) (Chromogranin B) (CgB) [Contains: GAWK peptide; CCB peptide].

PREX1_HUMAN
NC score	0.044173 (rank : 247)	θ value	4.03905 (rank : 228)
Query Neighborhood Hits	290	Target Neighborhood Hits	177	Shared Neighborhood Hits	48
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

FYB_MOUSE
NC score	0.043804 (rank : 248)	θ value	0.279714 (rank : 153)
Query Neighborhood Hits	290	Target Neighborhood Hits	194	Shared Neighborhood Hits	16
SwissProt Accessions	O35601, Q9Z2H3	Gene names	Fyb
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

WDR60_MOUSE
NC score	0.043586 (rank : 249)	θ value	1.81305 (rank : 201)
Query Neighborhood Hits	290	Target Neighborhood Hits	344	Shared Neighborhood Hits	45
SwissProt Accessions	Q8C761, Q3UNM4	Gene names	Wdr60
Domain Architecture	No domain graphic available
Description	WD repeat protein 60.

EZRI_MOUSE
NC score	0.043509 (rank : 250)	θ value	8.99809 (rank : 276)
Query Neighborhood Hits	290	Target Neighborhood Hits	693	Shared Neighborhood Hits	55
SwissProt Accessions	P26040, Q80ZT8, Q9DCI1	Gene names	Vil2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

SRRM2_MOUSE
NC score	0.043104 (rank : 251)	θ value	8.99809 (rank : 289)
Query Neighborhood Hits	290	Target Neighborhood Hits	1470	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

LUZP1_MOUSE
NC score	0.042078 (rank : 252)	θ value	0.0961366 (rank : 137)
Query Neighborhood Hits	290	Target Neighborhood Hits	940	Shared Neighborhood Hits	67
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

GOGA4_HUMAN
NC score	0.041022 (rank : 253)	θ value	0.21417 (rank : 149)
Query Neighborhood Hits	290	Target Neighborhood Hits	2034	Shared Neighborhood Hits	100
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

EVPL_HUMAN
NC score	0.040843 (rank : 254)	θ value	0.47712 (rank : 163)
Query Neighborhood Hits	290	Target Neighborhood Hits	895	Shared Neighborhood Hits	69
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

E41L2_HUMAN
NC score	0.038574 (rank : 255)	θ value	3.0926 (rank : 216)
Query Neighborhood Hits	290	Target Neighborhood Hits	287	Shared Neighborhood Hits	37
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

AXN2_HUMAN
NC score	0.038212 (rank : 256)	θ value	1.81305 (rank : 194)
Query Neighborhood Hits	290	Target Neighborhood Hits	102	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y2T1, Q9H3M6, Q9UH84	Gene names	AXIN2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

MAP1A_HUMAN
NC score	0.037178 (rank : 257)	θ value	1.81305 (rank : 198)
Query Neighborhood Hits	290	Target Neighborhood Hits	1626	Shared Neighborhood Hits	90
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

RBM13_MOUSE
NC score	0.036946 (rank : 258)	θ value	1.38821 (rank : 190)
Query Neighborhood Hits	290	Target Neighborhood Hits	63	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BGS0, Q921E0, Q9D5G6	Gene names	Rbm13
Domain Architecture	No domain graphic available
Description	MAK16-like protein RBM13 (RNA-binding motif protein 13).

TAD3L_MOUSE
NC score	0.036000 (rank : 259)	θ value	2.36792 (rank : 213)
Query Neighborhood Hits	290	Target Neighborhood Hits	188	Shared Neighborhood Hits	20
SwissProt Accessions	Q8R0L9, Q8CIH4, Q8K289, Q8R5E3, Q9CTJ0	Gene names	Tada3l, Ada3
Domain Architecture	No domain graphic available
Description	Transcriptional adapter 3-like (ADA3-like protein) (ADA3 homolog) (mADA3).

TAD3L_HUMAN
NC score	0.035860 (rank : 260)	θ value	2.36792 (rank : 212)
Query Neighborhood Hits	290	Target Neighborhood Hits	189	Shared Neighborhood Hits	20
SwissProt Accessions	O75528, Q9UFS2	Gene names	TADA3L, ADA3
Domain Architecture	No domain graphic available
Description	Transcriptional adapter 3-like (ADA3-like protein) (ADA3 homolog) (hADA3).

CN037_MOUSE
NC score	0.035485 (rank : 261)	θ value	2.36792 (rank : 205)
Query Neighborhood Hits	290	Target Neighborhood Hits	179	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BT18, Q8BFQ7, Q8R1Q5, Q9D6C5	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 homolog precursor.

GOGA4_MOUSE
NC score	0.035367 (rank : 262)	θ value	5.27518 (rank : 240)
Query Neighborhood Hits	290	Target Neighborhood Hits	1939	Shared Neighborhood Hits	94
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

BRE1A_MOUSE
NC score	0.035357 (rank : 263)	θ value	2.36792 (rank : 203)
Query Neighborhood Hits	290	Target Neighborhood Hits	1025	Shared Neighborhood Hits	61
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

IDLC_MOUSE
NC score	0.034553 (rank : 264)	θ value	5.27518 (rank : 241)
Query Neighborhood Hits	290	Target Neighborhood Hits	321	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BVN8	Gene names	Dnali1
Domain Architecture	No domain graphic available
Description	Axonemal dynein light intermediate polypeptide 1 (Inner dynein arm light chain, axonemal).

CT116_MOUSE
NC score	0.034551 (rank : 265)	θ value	5.27518 (rank : 239)
Query Neighborhood Hits	290	Target Neighborhood Hits	268	Shared Neighborhood Hits	30
SwissProt Accessions	Q80WW9, Q9CT52	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf116 homolog precursor.

CAF1A_MOUSE
NC score	0.034519 (rank : 266)	θ value	4.03905 (rank : 222)
Query Neighborhood Hits	290	Target Neighborhood Hits	736	Shared Neighborhood Hits	58
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

BAZ1A_HUMAN
NC score	0.034425 (rank : 267)	θ value	0.813845 (rank : 170)
Query Neighborhood Hits	290	Target Neighborhood Hits	693	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

PCNT_MOUSE
NC score	0.034382 (rank : 268)	θ value	2.36792 (rank : 209)
Query Neighborhood Hits	290	Target Neighborhood Hits	1207	Shared Neighborhood Hits	65
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

TCAL5_HUMAN
NC score	0.034283 (rank : 269)	θ value	5.27518 (rank : 248)
Query Neighborhood Hits	290	Target Neighborhood Hits	806	Shared Neighborhood Hits	48
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

CCD37_MOUSE
NC score	0.034037 (rank : 270)	θ value	2.36792 (rank : 204)
Query Neighborhood Hits	290	Target Neighborhood Hits	199	Shared Neighborhood Hits	21
SwissProt Accessions	Q80VN0, Q6AXD6	Gene names	Ccdc37
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 37.

IWS1_MOUSE
NC score	0.033830 (rank : 271)	θ value	3.0926 (rank : 218)
Query Neighborhood Hits	290	Target Neighborhood Hits	1258	Shared Neighborhood Hits	76
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MPP8_HUMAN
NC score	0.033605 (rank : 272)	θ value	1.06291 (rank : 182)
Query Neighborhood Hits	290	Target Neighborhood Hits	948	Shared Neighborhood Hits	65
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

BRE1A_HUMAN
NC score	0.032200 (rank : 273)	θ value	8.99809 (rank : 271)
Query Neighborhood Hits	290	Target Neighborhood Hits	1071	Shared Neighborhood Hits	62
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

ENAH_HUMAN
NC score	0.031890 (rank : 274)	θ value	6.88961 (rank : 259)
Query Neighborhood Hits	290	Target Neighborhood Hits	784	Shared Neighborhood Hits	52
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

TPR_HUMAN
NC score	0.031242 (rank : 275)	θ value	4.03905 (rank : 232)
Query Neighborhood Hits	290	Target Neighborhood Hits	1921	Shared Neighborhood Hits	103
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

FRM4A_MOUSE
NC score	0.031236 (rank : 276)	θ value	8.99809 (rank : 279)
Query Neighborhood Hits	290	Target Neighborhood Hits	108	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BIE6, Q6PDJ4, Q8CHA6	Gene names	Frmd4a, Frmd4, Kiaa1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

FRM4A_HUMAN
NC score	0.031206 (rank : 277)	θ value	8.99809 (rank : 278)
Query Neighborhood Hits	290	Target Neighborhood Hits	110	Shared Neighborhood Hits	12
SwissProt Accessions	Q9P2Q2	Gene names	FRMD4A, FRMD4, KIAA1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

RNPS1_HUMAN
NC score	0.030715 (rank : 278)	θ value	2.36792 (rank : 210)
Query Neighborhood Hits	290	Target Neighborhood Hits	285	Shared Neighborhood Hits	22
SwissProt Accessions	Q15287, O75308, Q8WY42, Q9NYG3	Gene names	RNPS1, LDC2
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2).

RNPS1_MOUSE
NC score	0.030715 (rank : 279)	θ value	2.36792 (rank : 211)
Query Neighborhood Hits	290	Target Neighborhood Hits	285	Shared Neighborhood Hits	22
SwissProt Accessions	Q99M28, Q3TMJ1, Q922H8	Gene names	Rnps1
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1.

CROCC_MOUSE
NC score	0.030514 (rank : 280)	θ value	6.88961 (rank : 256)
Query Neighborhood Hits	290	Target Neighborhood Hits	1460	Shared Neighborhood Hits	82
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

TRIPB_HUMAN
NC score	0.029584 (rank : 281)	θ value	2.36792 (rank : 214)
Query Neighborhood Hits	290	Target Neighborhood Hits	1587	Shared Neighborhood Hits	79
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

CING_MOUSE
NC score	0.029409 (rank : 282)	θ value	3.0926 (rank : 215)
Query Neighborhood Hits	290	Target Neighborhood Hits	1432	Shared Neighborhood Hits	76
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

CUTL1_MOUSE
NC score	0.029320 (rank : 283)	θ value	1.06291 (rank : 178)
Query Neighborhood Hits	290	Target Neighborhood Hits	1620	Shared Neighborhood Hits	74
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

CING_HUMAN
NC score	0.028237 (rank : 284)	θ value	8.99809 (rank : 273)
Query Neighborhood Hits	290	Target Neighborhood Hits	1275	Shared Neighborhood Hits	71
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

RBCC1_HUMAN
NC score	0.028232 (rank : 285)	θ value	6.88961 (rank : 268)
Query Neighborhood Hits	290	Target Neighborhood Hits	1023	Shared Neighborhood Hits	55
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

CASP_MOUSE
NC score	0.027509 (rank : 286)	θ value	1.81305 (rank : 195)
Query Neighborhood Hits	290	Target Neighborhood Hits	1152	Shared Neighborhood Hits	62
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

NKTR_HUMAN
NC score	0.027482 (rank : 287)	θ value	4.03905 (rank : 227)
Query Neighborhood Hits	290	Target Neighborhood Hits	658	Shared Neighborhood Hits	61
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

HOOK3_HUMAN
NC score	0.027083 (rank : 288)	θ value	6.88961 (rank : 261)
Query Neighborhood Hits	290	Target Neighborhood Hits	1070	Shared Neighborhood Hits	64
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

CF010_HUMAN
NC score	0.027022 (rank : 289)	θ value	5.27518 (rank : 238)
Query Neighborhood Hits	290	Target Neighborhood Hits	329	Shared Neighborhood Hits	36
SwissProt Accessions	Q5SRN2, Q5SPI9, Q5SPJ0, Q5SPK9, Q5SPL0, Q5SRN3, Q5TG25, Q5TG26, Q8N4B6	Gene names	C6orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf10.

TR150_HUMAN
NC score	0.026521 (rank : 290)	θ value	5.27518 (rank : 251)
Query Neighborhood Hits	290	Target Neighborhood Hits	313	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y2W1, Q5VTK6	Gene names	THRAP3, TRAP150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

NCOR1_MOUSE
NC score	0.026314 (rank : 291)	θ value	4.03905 (rank : 226)
Query Neighborhood Hits	290	Target Neighborhood Hits	521	Shared Neighborhood Hits	55
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

NC6IP_HUMAN
NC score	0.026172 (rank : 292)	θ value	0.62314 (rank : 169)
Query Neighborhood Hits	290	Target Neighborhood Hits	116	Shared Neighborhood Hits	10
SwissProt Accessions	Q96RS0, Q5GH23, Q8TDG9, Q96QU3, Q9H5V3	Gene names	NCOA6IP, PIMT
Domain Architecture	No domain graphic available
Description	Putative RNA methyltransferase NCOA6IP (EC 2.1.1.-) (Nuclear receptor coactivator 6-interacting protein) (PRIP-interacting protein with methyltransferase motif) (PIPMT) (PIMT) (CLL-associated antigen KW-2) (Hepatocellular carcinoma-associated antigen 137) (HCA137).

CCD37_HUMAN
NC score	0.025380 (rank : 293)	θ value	5.27518 (rank : 237)
Query Neighborhood Hits	290	Target Neighborhood Hits	248	Shared Neighborhood Hits	29
SwissProt Accessions	Q494V2, Q494V1, Q494V4, Q8N838	Gene names	CCDC37
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 37.

RAD50_MOUSE
NC score	0.025243 (rank : 294)	θ value	4.03905 (rank : 230)
Query Neighborhood Hits	290	Target Neighborhood Hits	1366	Shared Neighborhood Hits	76
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

RP1L1_MOUSE
NC score	0.025144 (rank : 295)	θ value	0.365318 (rank : 161)
Query Neighborhood Hits	290	Target Neighborhood Hits	170	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CGM2, Q8K0I4	Gene names	Rp1l1, Rp1hl1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein (Retinitis pigmentosa 1-like protein 1).

ANR12_HUMAN
NC score	0.025138 (rank : 296)	θ value	1.06291 (rank : 175)
Query Neighborhood Hits	290	Target Neighborhood Hits	1081	Shared Neighborhood Hits	65
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

ATRX_MOUSE
NC score	0.024247 (rank : 297)	θ value	8.99809 (rank : 270)
Query Neighborhood Hits	290	Target Neighborhood Hits	682	Shared Neighborhood Hits	63
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

DREB_MOUSE
NC score	0.024206 (rank : 298)	θ value	8.99809 (rank : 275)
Query Neighborhood Hits	290	Target Neighborhood Hits	446	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QXS6, Q922X1, Q9QXS5	Gene names	Dbn1, Drba
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

SFRS4_MOUSE
NC score	0.023933 (rank : 299)	θ value	8.99809 (rank : 288)
Query Neighborhood Hits	290	Target Neighborhood Hits	406	Shared Neighborhood Hits	41
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

MACF4_HUMAN
NC score	0.022946 (rank : 300)	θ value	1.06291 (rank : 181)
Query Neighborhood Hits	290	Target Neighborhood Hits	1321	Shared Neighborhood Hits	60
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

TRI12_MOUSE
NC score	0.022466 (rank : 301)	θ value	4.03905 (rank : 233)
Query Neighborhood Hits	290	Target Neighborhood Hits	387	Shared Neighborhood Hits	27
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

ATF6B_HUMAN
NC score	0.021290 (rank : 302)	θ value	0.62314 (rank : 166)
Query Neighborhood Hits	290	Target Neighborhood Hits	122	Shared Neighborhood Hits	7
SwissProt Accessions	Q99941, Q13269, Q14343, Q14345, Q99635, Q99637, Q9H3V9, Q9H3W1, Q9NPL0	Gene names	CREBL1, G13
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp) (Protein G13).

R3HD1_HUMAN
NC score	0.020142 (rank : 303)	θ value	3.0926 (rank : 219)
Query Neighborhood Hits	290	Target Neighborhood Hits	203	Shared Neighborhood Hits	12
SwissProt Accessions	Q15032, Q8IW32	Gene names	R3HDM1, KIAA0029, R3HDM
Domain Architecture	No domain graphic available
Description	R3H domain-containing protein 1.

MACF1_HUMAN
NC score	0.019976 (rank : 304)	θ value	1.06291 (rank : 180)
Query Neighborhood Hits	290	Target Neighborhood Hits	1341	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

LIMK2_MOUSE
NC score	0.019317 (rank : 305)	θ value	5.27518 (rank : 242)
Query Neighborhood Hits	290	Target Neighborhood Hits	998	Shared Neighborhood Hits	60
SwissProt Accessions	O54785, O54776, O55238, Q9QUL4	Gene names	Limk2
Domain Architecture
Description	LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2).

KIF4A_HUMAN
NC score	0.018867 (rank : 306)	θ value	1.81305 (rank : 197)
Query Neighborhood Hits	290	Target Neighborhood Hits	1159	Shared Neighborhood Hits	67
SwissProt Accessions	O95239, Q86TN3, Q86XX7, Q9NNY6, Q9NY24, Q9UMW3	Gene names	KIF4A, KIF4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

NCOR1_HUMAN
NC score	0.018665 (rank : 307)	θ value	4.03905 (rank : 225)
Query Neighborhood Hits	290	Target Neighborhood Hits	577	Shared Neighborhood Hits	41
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

ABCF1_HUMAN
NC score	0.018647 (rank : 308)	θ value	6.88961 (rank : 253)
Query Neighborhood Hits	290	Target Neighborhood Hits	343	Shared Neighborhood Hits	30
SwissProt Accessions	Q8NE71, O14897, Q69YP6	Gene names	ABCF1, ABC50
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50) (TNF-alpha-stimulated ABC protein).

SNPC4_MOUSE
NC score	0.018515 (rank : 309)	θ value	4.03905 (rank : 231)
Query Neighborhood Hits	290	Target Neighborhood Hits	237	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BP86, Q6PGG7, Q80UG9, Q810L1	Gene names	Snapc4
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit).

RN126_HUMAN
NC score	0.018485 (rank : 310)	θ value	8.99809 (rank : 285)
Query Neighborhood Hits	290	Target Neighborhood Hits	126	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BV68, Q9NWX1	Gene names	RNF126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

SYNE2_HUMAN
NC score	0.018361 (rank : 311)	θ value	5.27518 (rank : 246)
Query Neighborhood Hits	290	Target Neighborhood Hits	1323	Shared Neighborhood Hits	60
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

RUFY2_HUMAN
NC score	0.018219 (rank : 312)	θ value	8.99809 (rank : 286)
Query Neighborhood Hits	290	Target Neighborhood Hits	1208	Shared Neighborhood Hits	63
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

MRCKB_MOUSE
NC score	0.017442 (rank : 313)	θ value	0.813845 (rank : 173)
Query Neighborhood Hits	290	Target Neighborhood Hits	2180	Shared Neighborhood Hits	89
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

LAD1_MOUSE
NC score	0.017224 (rank : 314)	θ value	6.88961 (rank : 263)
Query Neighborhood Hits	290	Target Neighborhood Hits	391	Shared Neighborhood Hits	30
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

ASXL1_HUMAN
NC score	0.016527 (rank : 315)	θ value	5.27518 (rank : 236)
Query Neighborhood Hits	290	Target Neighborhood Hits	260	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IXJ9, Q5JWS9, Q8IYY7, Q9H466, Q9NQF8, Q9UFJ0, Q9UFP8, Q9Y2I4	Gene names	ASXL1, KIAA0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

MLL2_HUMAN
NC score	0.016139 (rank : 316)	θ value	6.88961 (rank : 264)
Query Neighborhood Hits	290	Target Neighborhood Hits	1788	Shared Neighborhood Hits	64
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MRCKB_HUMAN
NC score	0.015679 (rank : 317)	θ value	1.06291 (rank : 183)
Query Neighborhood Hits	290	Target Neighborhood Hits	2239	Shared Neighborhood Hits	93
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

EFNB3_HUMAN
NC score	0.015284 (rank : 318)	θ value	1.06291 (rank : 179)
Query Neighborhood Hits	290	Target Neighborhood Hits	48	Shared Neighborhood Hits	2
SwissProt Accessions	Q15768, O00680, Q8TBH7, Q92875	Gene names	EFNB3, EPLG8, LERK8
Domain Architecture
Description	Ephrin-B3 precursor (EPH-related receptor tyrosine kinase ligand 8) (LERK-8) (EPH-related receptor transmembrane ligand ELK-L3).

DC12_MOUSE
NC score	0.013982 (rank : 319)	θ value	6.88961 (rank : 257)
Query Neighborhood Hits	290	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R1M0	Gene names
Domain Architecture	No domain graphic available
Description	UPF0361 protein DC12 homolog.

ZCPW1_MOUSE
NC score	0.013974 (rank : 320)	θ value	8.99809 (rank : 290)
Query Neighborhood Hits	290	Target Neighborhood Hits	307	Shared Neighborhood Hits	23
SwissProt Accessions	Q6IR42	Gene names	Zcwpw1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1 homolog.

RM19_HUMAN
NC score	0.013246 (rank : 321)	θ value	5.27518 (rank : 245)
Query Neighborhood Hits	290	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	P49406, Q53TX9	Gene names	MRPL19, KIAA0104
Domain Architecture
Description	39S ribosomal protein L19, mitochondrial precursor (L19mt) (MRP-L19) (MRP-L15).

DC12_HUMAN
NC score	0.012680 (rank : 322)	θ value	8.99809 (rank : 274)
Query Neighborhood Hits	290	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q96FZ2, Q96G34, Q9NRP3	Gene names	C3orf37
Domain Architecture	No domain graphic available
Description	UPF0361 protein DC12.

RBP22_HUMAN
NC score	0.012298 (rank : 323)	θ value	3.0926 (rank : 220)
Query Neighborhood Hits	290	Target Neighborhood Hits	165	Shared Neighborhood Hits	12
SwissProt Accessions	Q53T03, Q53QN2, Q59GM7	Gene names	RANBP2L2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 2 (RanBP2L2).

DNJC3_HUMAN
NC score	0.010787 (rank : 324)	θ value	0.813845 (rank : 171)
Query Neighborhood Hits	290	Target Neighborhood Hits	223	Shared Neighborhood Hits	6
SwissProt Accessions	Q13217, Q86WT9, Q8N4N2	Gene names	DNAJC3, P58IPK, PRKRI
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 3 (Interferon-induced, double-stranded RNA-activated protein kinase inhibitor) (Protein kinase inhibitor p58) (Protein kinase inhibitor of 58 kDa).

K0831_HUMAN
NC score	0.010506 (rank : 325)	θ value	8.99809 (rank : 281)
Query Neighborhood Hits	290	Target Neighborhood Hits	203	Shared Neighborhood Hits	20
SwissProt Accessions	Q6ZNE5, O94920	Gene names	KIAA0831
Domain Architecture	No domain graphic available
Description	Protein KIAA0831.

OSBP2_MOUSE
NC score	0.010338 (rank : 326)	θ value	1.06291 (rank : 184)
Query Neighborhood Hits	290	Target Neighborhood Hits	150	Shared Neighborhood Hits	9
SwissProt Accessions	Q5QNQ6, Q8CF21	Gene names	Osbp2
Domain Architecture	No domain graphic available
Description	Oxysterol-binding protein 2.

ETV3_MOUSE
NC score	0.009499 (rank : 327)	θ value	2.36792 (rank : 206)
Query Neighborhood Hits	290	Target Neighborhood Hits	128	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R4Z4, Q9QZW1	Gene names	Etv3, Mets, Pe1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

CAMLG_HUMAN
NC score	0.009459 (rank : 328)	θ value	8.99809 (rank : 272)
Query Neighborhood Hits	290	Target Neighborhood Hits	15	Shared Neighborhood Hits	5
SwissProt Accessions	P49069	Gene names	CAMLG, CAML
Domain Architecture	No domain graphic available
Description	Calcium signal-modulating cyclophilin ligand (CAML).

L2GL1_MOUSE
NC score	0.008889 (rank : 329)	θ value	2.36792 (rank : 208)
Query Neighborhood Hits	290	Target Neighborhood Hits	70	Shared Neighborhood Hits	2
SwissProt Accessions	Q80Y17, Q61856, Q7TNV3, Q8BN92	Gene names	Llgl1, Llglh
Domain Architecture	No domain graphic available
Description	Lethal(2) giant larvae protein homolog 1 (LLGL) (Mlgl) (Mgl-1).

INOC1_HUMAN
NC score	0.008289 (rank : 330)	θ value	6.88961 (rank : 262)
Query Neighborhood Hits	290	Target Neighborhood Hits	181	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ULG1, Q9NTG6	Gene names	INOC1, KIAA1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-) (hINO80).

M4K4_HUMAN
NC score	0.007920 (rank : 331)	θ value	8.99809 (rank : 282)
Query Neighborhood Hits	290	Target Neighborhood Hits	1589	Shared Neighborhood Hits	66
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

CD2L1_HUMAN
NC score	0.007029 (rank : 332)	θ value	6.88961 (rank : 254)
Query Neighborhood Hits	290	Target Neighborhood Hits	1467	Shared Neighborhood Hits	68
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

TB22A_MOUSE
NC score	0.006749 (rank : 333)	θ value	6.88961 (rank : 269)
Query Neighborhood Hits	290	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R5A6, Q3U268, Q3U3T0, Q8CA49	Gene names	Tbc1d22a, D15Ertd781e
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 22A.

K2C5_MOUSE
NC score	0.006336 (rank : 334)	θ value	1.81305 (rank : 196)
Query Neighborhood Hits	290	Target Neighborhood Hits	505	Shared Neighborhood Hits	31
SwissProt Accessions	Q922U2, Q920F2	Gene names	Krt5, Krt2-5
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 5 (Cytokeratin-5) (CK-5) (Keratin-5) (K5).

TRPM7_MOUSE
NC score	0.006296 (rank : 335)	θ value	4.03905 (rank : 234)
Query Neighborhood Hits	290	Target Neighborhood Hits	113	Shared Neighborhood Hits	8
SwissProt Accessions	Q923J1, Q8C7S7, Q8CE54, Q921Y5, Q925B2, Q9CUT2, Q9JLQ1	Gene names	Trpm7, Chak, Ltrpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1) (Transient receptor potential-phospholipase C- interacting kinase) (TRP-PLIK).

CD2L2_HUMAN
NC score	0.005536 (rank : 336)	θ value	6.88961 (rank : 255)
Query Neighborhood Hits	290	Target Neighborhood Hits	1439	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

RAVR1_MOUSE
NC score	0.003393 (rank : 337)	θ value	6.88961 (rank : 267)
Query Neighborhood Hits	290	Target Neighborhood Hits	179	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CW46, Q5DTT6, Q811K0, Q8C3Z1, Q8CA14	Gene names	Raver1, Kiaa1978
Domain Architecture	No domain graphic available
Description	Ribonucleoprotein PTB-binding 1 (Protein raver-1).

FGRL1_HUMAN
NC score	0.001563 (rank : 338)	θ value	6.88961 (rank : 260)
Query Neighborhood Hits	290	Target Neighborhood Hits	335	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N441, Q6PJN1, Q9BXN7, Q9H4D7	Gene names	FGFRL1, FGFR5, FHFR
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5) (FGFR-like protein) (FGF homologous factor receptor).

FGRL1_MOUSE
NC score	0.001162 (rank : 339)	θ value	8.99809 (rank : 277)
Query Neighborhood Hits	290	Target Neighborhood Hits	325	Shared Neighborhood Hits	5
SwissProt Accessions	Q91V87, Q920C2, Q920C3	Gene names	Fgfrl1, Fgfr5
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5).

OBSCN_HUMAN
NC score	-0.000465 (rank : 340)	θ value	8.99809 (rank : 283)
Query Neighborhood Hits	290	Target Neighborhood Hits	1931	Shared Neighborhood Hits	41
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

DDX3Y_HUMAN
NC score	-0.000638 (rank : 341)	θ value	6.88961 (rank : 258)
Query Neighborhood Hits	290	Target Neighborhood Hits	121	Shared Neighborhood Hits	2
SwissProt Accessions	O15523, Q8IYV7	Gene names	DDX3Y, DBY
Domain Architecture
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal).

FGFR3_MOUSE
NC score	-0.004839 (rank : 342)	θ value	3.0926 (rank : 217)
Query Neighborhood Hits	290	Target Neighborhood Hits	1059	Shared Neighborhood Hits	17
SwissProt Accessions	Q61851, Q61564, Q63834	Gene names	Fgfr3, Mfr3, Sam3
Domain Architecture
Description	Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1) (FGFR-3) (Heparin-binding growth factor receptor) (CD333 antigen).

ZKSC1_HUMAN
NC score	-0.007910 (rank : 343)	θ value	5.27518 (rank : 252)
Query Neighborhood Hits	290	Target Neighborhood Hits	949	Shared Neighborhood Hits	29
SwissProt Accessions	P17029, P52745, Q8TBW5, Q8TEK7	Gene names	ZKSCAN1, KOX18, ZNF139, ZNF36
Domain Architecture	No domain graphic available
Description	Zinc finger with KRAB and SCAN domain-containing protein 1 (Zinc finger protein 36) (Zinc finger protein KOX18).

ZN275_HUMAN
NC score	-0.008662 (rank : 344)	θ value	4.03905 (rank : 235)
Query Neighborhood Hits	290	Target Neighborhood Hits	761	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NSD4	Gene names	ZNF275
Domain Architecture	No domain graphic available
Description	Zinc finger protein 275.