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Network neighborhood for query Sequence : OSBP2_MOUSE

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OSBP2_MOUSE
SwissProt Accessions	Q5QNQ6, Q8CF21	Gene names	Osbp2
Domain Architecture	No domain graphic available
Description	Oxysterol-binding protein 2.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

OSBP1_HUMAN
θ value	0 (rank : 1)	NC score	0.972015 (rank : 3)
Query Neighborhood Hits	150	Target Neighborhood Hits	180	Shared Neighborhood Hits	69
SwissProt Accessions	P22059	Gene names	OSBP, OSBP1
Domain Architecture
Description	Oxysterol-binding protein 1.

OSBP2_HUMAN
θ value	0 (rank : 2)	NC score	0.985261 (rank : 2)
Query Neighborhood Hits	150	Target Neighborhood Hits	154	Shared Neighborhood Hits	72
SwissProt Accessions	Q969R2, O60396, Q9BY96, Q9BZF0	Gene names	OSBP2, KIAA1664, ORP4, OSBPL4
Domain Architecture
Description	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).

OSBP2_MOUSE
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	150	Target Neighborhood Hits	150	Shared Neighborhood Hits	150
SwissProt Accessions	Q5QNQ6, Q8CF21	Gene names	Osbp2
Domain Architecture	No domain graphic available
Description	Oxysterol-binding protein 2.

OSBL1_MOUSE
θ value	1.82896e-85 (rank : 4)	NC score	0.641164 (rank : 18)
Query Neighborhood Hits	150	Target Neighborhood Hits	336	Shared Neighborhood Hits	32
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

OSBL1_HUMAN
θ value	2.38869e-85 (rank : 5)	NC score	0.626172 (rank : 19)
Query Neighborhood Hits	150	Target Neighborhood Hits	368	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

OSBL6_HUMAN
θ value	3.23591e-74 (rank : 6)	NC score	0.890323 (rank : 9)
Query Neighborhood Hits	150	Target Neighborhood Hits	101	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BZF3, Q7Z4Q1, Q96SR1	Gene names	OSBPL6, ORP6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

OSBL2_HUMAN
θ value	7.20884e-74 (rank : 7)	NC score	0.907733 (rank : 4)
Query Neighborhood Hits	150	Target Neighborhood Hits	23	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H1P3, Q9BZB1, Q9Y4B8	Gene names	OSBPL2, KIAA0772, ORP2
Domain Architecture
Description	Oxysterol-binding protein-related protein 2 (OSBP-related protein 2) (ORP-2).

OSBL6_MOUSE
θ value	3.57772e-73 (rank : 8)	NC score	0.888600 (rank : 10)
Query Neighborhood Hits	150	Target Neighborhood Hits	105	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BXR9, Q8BYW2	Gene names	Osbpl6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

OSBL2_MOUSE
θ value	1.35953e-72 (rank : 9)	NC score	0.907485 (rank : 5)
Query Neighborhood Hits	150	Target Neighborhood Hits	22	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BX94, Q3TCK8, Q8R0H8	Gene names	Osbpl2
Domain Architecture
Description	Oxysterol-binding protein-related protein 2 (OSBP-related protein 2) (ORP-2).

OSBL3_MOUSE
θ value	5.71191e-71 (rank : 10)	NC score	0.895243 (rank : 7)
Query Neighborhood Hits	150	Target Neighborhood Hits	86	Shared Neighborhood Hits	45
SwissProt Accessions	Q9DBS9	Gene names	Osbpl3, Orp3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

OSBL3_HUMAN
θ value	1.66191e-70 (rank : 11)	NC score	0.892414 (rank : 8)
Query Neighborhood Hits	150	Target Neighborhood Hits	93	Shared Neighborhood Hits	45
SwissProt Accessions	Q9H4L5, O14591, O43357, O43358, Q8N702, Q8N703, Q8N704, Q8NFH0, Q8NFH1, Q8NI12, Q8NI13, Q9BZF4, Q9UED6	Gene names	OSBPL3, KIAA0704, ORP3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

OSBL7_HUMAN
θ value	5.53243e-66 (rank : 12)	NC score	0.901147 (rank : 6)
Query Neighborhood Hits	150	Target Neighborhood Hits	71	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BZF2	Gene names	OSBPL7, ORP7
Domain Architecture
Description	Oxysterol-binding protein-related protein 7 (OSBP-related protein 7) (ORP-7).

OSBL5_HUMAN
θ value	5.42112e-21 (rank : 13)	NC score	0.683419 (rank : 11)
Query Neighborhood Hits	150	Target Neighborhood Hits	117	Shared Neighborhood Hits	28
SwissProt Accessions	Q9H0X9, Q9BZB0, Q9P1Z4	Gene names	OSBPL5, KIAA1534, ORP5
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5).

OSBL5_MOUSE
θ value	2.5182e-18 (rank : 14)	NC score	0.678707 (rank : 12)
Query Neighborhood Hits	150	Target Neighborhood Hits	77	Shared Neighborhood Hits	27
SwissProt Accessions	Q9ER64, Q8R510, Q99NF5	Gene names	Osbpl5, Obph1, Osbp2
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5) (Oxysterol-binding protein homolog 1).

OSBL8_HUMAN
θ value	3.28887e-18 (rank : 15)	NC score	0.664424 (rank : 15)
Query Neighborhood Hits	150	Target Neighborhood Hits	289	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

OSB11_MOUSE
θ value	1.80466e-16 (rank : 16)	NC score	0.661808 (rank : 16)
Query Neighborhood Hits	150	Target Neighborhood Hits	71	Shared Neighborhood Hits	36
SwissProt Accessions	Q8CI95	Gene names	Osbpl11
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

PKHA3_MOUSE
θ value	1.99529e-15 (rank : 17)	NC score	0.538893 (rank : 20)
Query Neighborhood Hits	150	Target Neighborhood Hits	67	Shared Neighborhood Hits	43
SwissProt Accessions	Q9ERS4	Gene names	Plekha3, Fapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

OSB11_HUMAN
θ value	7.58209e-15 (rank : 18)	NC score	0.651702 (rank : 17)
Query Neighborhood Hits	150	Target Neighborhood Hits	60	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BXB4	Gene names	OSBPL11, ORP11, OSBP12
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

PKHA3_HUMAN
θ value	1.2105e-12 (rank : 19)	NC score	0.519765 (rank : 21)
Query Neighborhood Hits	150	Target Neighborhood Hits	66	Shared Neighborhood Hits	43
SwissProt Accessions	Q9HB20, Q86TQ1, Q9NXT3	Gene names	PLEKHA3, FAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

OSB10_HUMAN
θ value	7.84624e-12 (rank : 20)	NC score	0.666123 (rank : 14)
Query Neighborhood Hits	150	Target Neighborhood Hits	55	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BXB5, Q9BTU5	Gene names	OSBPL10, ORP10, OSBP9
Domain Architecture
Description	Oxysterol-binding protein-related protein 10 (OSBP-related protein 10) (ORP-10).

C43BP_HUMAN
θ value	5.08577e-11 (rank : 21)	NC score	0.462692 (rank : 22)
Query Neighborhood Hits	150	Target Neighborhood Hits	87	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y5P4, Q96Q85, Q96Q88, Q9H2S7, Q9H2S8	Gene names	COL4A3BP, STARD11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

C43BP_MOUSE
θ value	5.08577e-11 (rank : 22)	NC score	0.459368 (rank : 23)
Query Neighborhood Hits	150	Target Neighborhood Hits	91	Shared Neighborhood Hits	52
SwissProt Accessions	Q9EQG9, Q91WB1, Q9CU52, Q9EQG8	Gene names	Col4a3bp, Stard11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

OSBL9_HUMAN
θ value	6.21693e-09 (rank : 23)	NC score	0.673269 (rank : 13)
Query Neighborhood Hits	150	Target Neighborhood Hits	138	Shared Neighborhood Hits	52
SwissProt Accessions	Q96SU4, Q9H9X2	Gene names	OSBPL9, ORP9, OSBP4
Domain Architecture
Description	Oxysterol-binding protein-related protein 9 (OSBP-related protein 9) (ORP-9).

MYO10_HUMAN
θ value	0.00175202 (rank : 24)	NC score	0.068575 (rank : 62)
Query Neighborhood Hits	150	Target Neighborhood Hits	920	Shared Neighborhood Hits	76
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

DGKK_HUMAN
θ value	0.00298849 (rank : 25)	NC score	0.037706 (rank : 80)
Query Neighborhood Hits	150	Target Neighborhood Hits	378	Shared Neighborhood Hits	23
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

TARA_MOUSE
θ value	0.00665767 (rank : 26)	NC score	0.103674 (rank : 39)
Query Neighborhood Hits	150	Target Neighborhood Hits	1133	Shared Neighborhood Hits	74
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

VITRN_HUMAN
θ value	0.00665767 (rank : 27)	NC score	0.025918 (rank : 89)
Query Neighborhood Hits	150	Target Neighborhood Hits	63	Shared Neighborhood Hits	2
SwissProt Accessions	Q6UXI7, Q6P7T3, Q96DT1	Gene names	VIT
Domain Architecture	No domain graphic available
Description	Vitrin precursor.

DDEF1_MOUSE
θ value	0.00869519 (rank : 28)	NC score	0.115550 (rank : 28)
Query Neighborhood Hits	150	Target Neighborhood Hits	592	Shared Neighborhood Hits	39
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

PKHA6_HUMAN
θ value	0.00869519 (rank : 29)	NC score	0.147643 (rank : 24)
Query Neighborhood Hits	150	Target Neighborhood Hits	556	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA2_MOUSE
θ value	0.0330416 (rank : 30)	NC score	0.117691 (rank : 26)
Query Neighborhood Hits	150	Target Neighborhood Hits	116	Shared Neighborhood Hits	48
SwissProt Accessions	Q9ERS5, Q8BY29	Gene names	Plekha2, Tapp2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2) (PH domain-containing adaptor PHAD47).

PKHA6_MOUSE
θ value	0.0431538 (rank : 31)	NC score	0.138585 (rank : 25)
Query Neighborhood Hits	150	Target Neighborhood Hits	591	Shared Neighborhood Hits	64
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

MRIP_MOUSE
θ value	0.0563607 (rank : 32)	NC score	0.090001 (rank : 48)
Query Neighborhood Hits	150	Target Neighborhood Hits	569	Shared Neighborhood Hits	51
SwissProt Accessions	P97434, Q3TBR5, Q3TC85, Q3TRS0, Q3U1Y8, Q3U3E4, Q5SWZ3, Q5SWZ4, Q5SWZ7, Q6P559, Q80YC8	Gene names	Mrip, Kiaa0864, Rhoip3
Domain Architecture
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (p116Rip) (RIP3).

CEND2_HUMAN
θ value	0.0736092 (rank : 33)	NC score	0.070578 (rank : 60)
Query Neighborhood Hits	150	Target Neighborhood Hits	166	Shared Neighborhood Hits	39
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

DDEF2_HUMAN
θ value	0.0961366 (rank : 34)	NC score	0.083483 (rank : 51)
Query Neighborhood Hits	150	Target Neighborhood Hits	599	Shared Neighborhood Hits	39
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
θ value	0.0961366 (rank : 35)	NC score	0.082877 (rank : 52)
Query Neighborhood Hits	150	Target Neighborhood Hits	625	Shared Neighborhood Hits	38
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

PKHA4_HUMAN
θ value	0.0961366 (rank : 36)	NC score	0.116601 (rank : 27)
Query Neighborhood Hits	150	Target Neighborhood Hits	283	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

DAPP1_MOUSE
θ value	0.125558 (rank : 37)	NC score	0.086606 (rank : 49)
Query Neighborhood Hits	150	Target Neighborhood Hits	225	Shared Neighborhood Hits	49
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

GAB2_MOUSE
θ value	0.125558 (rank : 38)	NC score	0.105862 (rank : 36)
Query Neighborhood Hits	150	Target Neighborhood Hits	220	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

MDC1_MOUSE
θ value	0.163984 (rank : 39)	NC score	0.030710 (rank : 84)
Query Neighborhood Hits	150	Target Neighborhood Hits	998	Shared Neighborhood Hits	49
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MRIP_HUMAN
θ value	0.163984 (rank : 40)	NC score	0.082294 (rank : 53)
Query Neighborhood Hits	150	Target Neighborhood Hits	578	Shared Neighborhood Hits	56
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

RHG25_MOUSE
θ value	0.163984 (rank : 41)	NC score	0.095471 (rank : 42)
Query Neighborhood Hits	150	Target Neighborhood Hits	492	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

PKHB1_MOUSE
θ value	0.21417 (rank : 42)	NC score	0.111993 (rank : 29)
Query Neighborhood Hits	150	Target Neighborhood Hits	47	Shared Neighborhood Hits	32
SwissProt Accessions	Q9QYE9, Q9QYB3, Q9QYB4, Q9QYD2, Q9QYD3	Gene names	Plekhb1, Phr1
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 1 (Pleckstrin homology domain retinal protein 1) (PH domain-containing protein in retina 1) (PHRET1).

WNK2_HUMAN
θ value	0.21417 (rank : 43)	NC score	0.005801 (rank : 147)
Query Neighborhood Hits	150	Target Neighborhood Hits	1407	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

MAP1A_HUMAN
θ value	0.279714 (rank : 44)	NC score	0.024624 (rank : 90)
Query Neighborhood Hits	150	Target Neighborhood Hits	1626	Shared Neighborhood Hits	47
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

PKHA4_MOUSE
θ value	0.279714 (rank : 45)	NC score	0.109662 (rank : 32)
Query Neighborhood Hits	150	Target Neighborhood Hits	202	Shared Neighborhood Hits	44
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

SWP70_MOUSE
θ value	0.279714 (rank : 46)	NC score	0.105374 (rank : 37)
Query Neighborhood Hits	150	Target Neighborhood Hits	1097	Shared Neighborhood Hits	80
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

PKHA2_HUMAN
θ value	0.365318 (rank : 47)	NC score	0.110348 (rank : 30)
Query Neighborhood Hits	150	Target Neighborhood Hits	119	Shared Neighborhood Hits	47
SwissProt Accessions	Q9HB19	Gene names	PLEKHA2, TAPP2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2).

PKHB1_HUMAN
θ value	0.365318 (rank : 48)	NC score	0.109183 (rank : 35)
Query Neighborhood Hits	150	Target Neighborhood Hits	46	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UF11, Q9UBF5, Q9UI37, Q9UI44	Gene names	PLEKHB1, KPL1, PHR1
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 1 (Pleckstrin homology domain retinal protein 1) (PH domain-containing protein in retina 1) (PHRET1).

SWP70_HUMAN
θ value	0.365318 (rank : 49)	NC score	0.109216 (rank : 34)
Query Neighborhood Hits	150	Target Neighborhood Hits	973	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

TARA_HUMAN
θ value	0.365318 (rank : 50)	NC score	0.069115 (rank : 61)
Query Neighborhood Hits	150	Target Neighborhood Hits	1626	Shared Neighborhood Hits	82
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

CYH3_MOUSE
θ value	0.47712 (rank : 51)	NC score	0.080951 (rank : 56)
Query Neighborhood Hits	150	Target Neighborhood Hits	148	Shared Neighborhood Hits	51
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

CYH4_HUMAN
θ value	0.47712 (rank : 52)	NC score	0.093902 (rank : 45)
Query Neighborhood Hits	150	Target Neighborhood Hits	135	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UIA0, Q5R3F9, Q9UGT6	Gene names	PSCD4, CYT4
Domain Architecture
Description	Cytohesin-4.

CYH4_MOUSE
θ value	0.47712 (rank : 53)	NC score	0.095071 (rank : 43)
Query Neighborhood Hits	150	Target Neighborhood Hits	134	Shared Neighborhood Hits	49
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

SGIP1_MOUSE
θ value	0.47712 (rank : 54)	NC score	0.028513 (rank : 86)
Query Neighborhood Hits	150	Target Neighborhood Hits	180	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

CO4A2_MOUSE
θ value	0.62314 (rank : 55)	NC score	0.005481 (rank : 149)
Query Neighborhood Hits	150	Target Neighborhood Hits	492	Shared Neighborhood Hits	10
SwissProt Accessions	P08122, Q61375	Gene names	Col4a2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

DAPP1_HUMAN
θ value	0.62314 (rank : 56)	NC score	0.075737 (rank : 57)
Query Neighborhood Hits	150	Target Neighborhood Hits	227	Shared Neighborhood Hits	48
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DREB_MOUSE
θ value	0.62314 (rank : 57)	NC score	0.044056 (rank : 78)
Query Neighborhood Hits	150	Target Neighborhood Hits	446	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QXS6, Q922X1, Q9QXS5	Gene names	Dbn1, Drba
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

GAB2_HUMAN
θ value	0.62314 (rank : 58)	NC score	0.091808 (rank : 47)
Query Neighborhood Hits	150	Target Neighborhood Hits	188	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UQC2, O60317	Gene names	GAB2, KIAA0571
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (pp100).

PKHA1_HUMAN
θ value	0.62314 (rank : 59)	NC score	0.103800 (rank : 38)
Query Neighborhood Hits	150	Target Neighborhood Hits	127	Shared Neighborhood Hits	48
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

RHG25_HUMAN
θ value	0.62314 (rank : 60)	NC score	0.094311 (rank : 44)
Query Neighborhood Hits	150	Target Neighborhood Hits	550	Shared Neighborhood Hits	64
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

CEND1_HUMAN
θ value	0.813845 (rank : 61)	NC score	0.067399 (rank : 63)
Query Neighborhood Hits	150	Target Neighborhood Hits	284	Shared Neighborhood Hits	49
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

DREB_HUMAN
θ value	0.813845 (rank : 62)	NC score	0.041285 (rank : 79)
Query Neighborhood Hits	150	Target Neighborhood Hits	450	Shared Neighborhood Hits	15
SwissProt Accessions	Q16643	Gene names	DBN1
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

GCC2_MOUSE
θ value	0.813845 (rank : 63)	NC score	0.017117 (rank : 109)
Query Neighborhood Hits	150	Target Neighborhood Hits	1619	Shared Neighborhood Hits	43
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

MLL2_HUMAN
θ value	0.813845 (rank : 64)	NC score	0.019220 (rank : 102)
Query Neighborhood Hits	150	Target Neighborhood Hits	1788	Shared Neighborhood Hits	50
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MTMRD_HUMAN
θ value	0.813845 (rank : 65)	NC score	0.092451 (rank : 46)
Query Neighborhood Hits	150	Target Neighborhood Hits	135	Shared Neighborhood Hits	46
SwissProt Accessions	Q86WG5, Q3MJF0, Q68DQ3, Q6P459, Q6PJD1, Q7Z325, Q7Z621, Q86VE2, Q96FE2, Q9C097	Gene names	SBF2, CMT4B2, KIAA1766, MTMR13
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 13 (SET-binding factor 2).

TPR_HUMAN
θ value	0.813845 (rank : 66)	NC score	0.019680 (rank : 101)
Query Neighborhood Hits	150	Target Neighborhood Hits	1921	Shared Neighborhood Hits	51
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

URP2_MOUSE
θ value	0.813845 (rank : 67)	NC score	0.071971 (rank : 59)
Query Neighborhood Hits	150	Target Neighborhood Hits	37	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K1B8	Gene names	Urp2, Kind3
Domain Architecture
Description	Unc-112-related protein 2 (Kindlin-3).

ATS7_HUMAN
θ value	1.06291 (rank : 68)	NC score	0.005191 (rank : 150)
Query Neighborhood Hits	150	Target Neighborhood Hits	169	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

BSN_HUMAN
θ value	1.06291 (rank : 69)	NC score	0.024617 (rank : 91)
Query Neighborhood Hits	150	Target Neighborhood Hits	1537	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

DOCK9_HUMAN
θ value	1.06291 (rank : 70)	NC score	0.032686 (rank : 81)
Query Neighborhood Hits	150	Target Neighborhood Hits	82	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BZ29, Q5JUD4, Q5JUD6, Q5T2Q1, Q5TAN8, Q9BZ25, Q9BZ26, Q9BZ27, Q9BZ28, Q9UPU4	Gene names	DOCK9, KIAA1058
Domain Architecture
Description	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin 1).

PARD3_MOUSE
θ value	1.06291 (rank : 71)	NC score	0.010338 (rank : 132)
Query Neighborhood Hits	150	Target Neighborhood Hits	290	Shared Neighborhood Hits	9
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

RASA2_MOUSE
θ value	1.06291 (rank : 72)	NC score	0.026149 (rank : 88)
Query Neighborhood Hits	150	Target Neighborhood Hits	159	Shared Neighborhood Hits	24
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

UBP25_HUMAN
θ value	1.06291 (rank : 73)	NC score	0.013334 (rank : 127)
Query Neighborhood Hits	150	Target Neighborhood Hits	124	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UHP3, Q9H9W1	Gene names	USP25, USP21
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (USP on chromosome 21).

AFF2_HUMAN
θ value	1.38821 (rank : 74)	NC score	0.016011 (rank : 116)
Query Neighborhood Hits	150	Target Neighborhood Hits	218	Shared Neighborhood Hits	14
SwissProt Accessions	P51816, O43786, O60215, P78407, Q13521, Q14323, Q9UNA5	Gene names	AFF2, FMR2, OX19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation 2 protein) (Protein FMR-2) (FMR2P) (Protein Ox19) (Fragile X E mental retardation syndrome protein).

AKT1_HUMAN
θ value	1.38821 (rank : 75)	NC score	0.005758 (rank : 148)
Query Neighborhood Hits	150	Target Neighborhood Hits	885	Shared Neighborhood Hits	35
SwissProt Accessions	P31749, Q9BWB6	Gene names	AKT1, PKB, RAC
Domain Architecture
Description	RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-alpha) (Protein kinase B) (PKB) (C-AKT).

FARP1_HUMAN
θ value	1.38821 (rank : 76)	NC score	0.031903 (rank : 82)
Query Neighborhood Hits	150	Target Neighborhood Hits	241	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

PKHA5_HUMAN
θ value	1.38821 (rank : 77)	NC score	0.099615 (rank : 40)
Query Neighborhood Hits	150	Target Neighborhood Hits	455	Shared Neighborhood Hits	57
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

PKHB2_MOUSE
θ value	1.38821 (rank : 78)	NC score	0.081276 (rank : 55)
Query Neighborhood Hits	150	Target Neighborhood Hits	48	Shared Neighborhood Hits	29
SwissProt Accessions	Q9QZC7, Q3UDH6, Q8C4I4, Q8CA27	Gene names	Plekhb2, Evt2
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 2 (Evectin-2).

PXK_HUMAN
θ value	1.38821 (rank : 79)	NC score	0.024146 (rank : 92)
Query Neighborhood Hits	150	Target Neighborhood Hits	216	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z7A4, Q3BCH4, Q3BCH5, Q3BCH6, Q3BDW1, Q45L83, Q59EX3, Q6PK17, Q6ZN39, Q96CA3, Q96R07, Q9NXB8	Gene names	PXK
Domain Architecture	No domain graphic available
Description	PX domain-containing protein kinase-like protein (Modulator of Na,K- ATPase) (MONaKA).

RD23B_MOUSE
θ value	1.38821 (rank : 80)	NC score	0.020578 (rank : 99)
Query Neighborhood Hits	150	Target Neighborhood Hits	189	Shared Neighborhood Hits	14
SwissProt Accessions	P54728	Gene names	Rad23b, Mhr23b
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (mHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

RERE_MOUSE
θ value	1.38821 (rank : 81)	NC score	0.016240 (rank : 114)
Query Neighborhood Hits	150	Target Neighborhood Hits	785	Shared Neighborhood Hits	28
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

RP1L1_HUMAN
θ value	1.38821 (rank : 82)	NC score	0.017235 (rank : 108)
Query Neighborhood Hits	150	Target Neighborhood Hits	1072	Shared Neighborhood Hits	33
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

SNCAP_HUMAN
θ value	1.38821 (rank : 83)	NC score	0.022822 (rank : 93)
Query Neighborhood Hits	150	Target Neighborhood Hits	313	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y6H5	Gene names	SNCAIP
Domain Architecture
Description	Synphilin-1 (Alpha-synuclein-interacting protein).

BAT3_HUMAN
θ value	1.81305 (rank : 84)	NC score	0.019834 (rank : 100)
Query Neighborhood Hits	150	Target Neighborhood Hits	490	Shared Neighborhood Hits	20
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

BSN_MOUSE
θ value	1.81305 (rank : 85)	NC score	0.027098 (rank : 87)
Query Neighborhood Hits	150	Target Neighborhood Hits	2057	Shared Neighborhood Hits	69
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CUTL2_MOUSE
θ value	1.81305 (rank : 86)	NC score	0.013961 (rank : 122)
Query Neighborhood Hits	150	Target Neighborhood Hits	771	Shared Neighborhood Hits	25
SwissProt Accessions	P70298	Gene names	Cutl2
Domain Architecture
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

ENAH_MOUSE
θ value	1.81305 (rank : 87)	NC score	0.017416 (rank : 107)
Query Neighborhood Hits	150	Target Neighborhood Hits	919	Shared Neighborhood Hits	35
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

GCC2_HUMAN
θ value	1.81305 (rank : 88)	NC score	0.017703 (rank : 106)
Query Neighborhood Hits	150	Target Neighborhood Hits	1558	Shared Neighborhood Hits	40
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

K0082_HUMAN
θ value	1.81305 (rank : 89)	NC score	0.016438 (rank : 113)
Query Neighborhood Hits	150	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N1G2, Q14670, Q96FJ9	Gene names	KIAA0082
Domain Architecture	No domain graphic available
Description	Protein KIAA0082.

NCOR1_MOUSE
θ value	1.81305 (rank : 90)	NC score	0.016542 (rank : 112)
Query Neighborhood Hits	150	Target Neighborhood Hits	521	Shared Neighborhood Hits	27
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

PLEK2_MOUSE
θ value	1.81305 (rank : 91)	NC score	0.110032 (rank : 31)
Query Neighborhood Hits	150	Target Neighborhood Hits	96	Shared Neighborhood Hits	41
SwissProt Accessions	Q9WV52	Gene names	Plek2
Domain Architecture
Description	Pleckstrin-2.

RBP24_HUMAN
θ value	1.81305 (rank : 92)	NC score	0.017734 (rank : 105)
Query Neighborhood Hits	150	Target Neighborhood Hits	1559	Shared Neighborhood Hits	40
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

NPAS2_MOUSE
θ value	2.36792 (rank : 93)	NC score	0.010216 (rank : 133)
Query Neighborhood Hits	150	Target Neighborhood Hits	132	Shared Neighborhood Hits	7
SwissProt Accessions	P97460	Gene names	Npas2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2).

PLEK2_HUMAN
θ value	2.36792 (rank : 94)	NC score	0.109535 (rank : 33)
Query Neighborhood Hits	150	Target Neighborhood Hits	101	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

PXK_MOUSE
θ value	2.36792 (rank : 95)	NC score	0.022017 (rank : 96)
Query Neighborhood Hits	150	Target Neighborhood Hits	320	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BX57, Q3TD60, Q3TEL7, Q3TZZ1, Q3U197, Q3U773, Q3UCS5, Q4FBH7, Q91WB6	Gene names	Pxk
Domain Architecture	No domain graphic available
Description	PX domain-containing protein kinase-like protein (Modulator of Na,K- ATPase) (MONaKA).

ZN318_HUMAN
θ value	2.36792 (rank : 96)	NC score	0.016184 (rank : 115)
Query Neighborhood Hits	150	Target Neighborhood Hits	497	Shared Neighborhood Hits	16
SwissProt Accessions	Q5VUA4, O94796, Q4G0E4, Q8NEM6, Q9UNU8, Q9Y2W9	Gene names	ZNF318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Endocrine regulatory protein).

ATX7_MOUSE
θ value	3.0926 (rank : 97)	NC score	0.014133 (rank : 120)
Query Neighborhood Hits	150	Target Neighborhood Hits	328	Shared Neighborhood Hits	9
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

BRE1B_HUMAN
θ value	3.0926 (rank : 98)	NC score	0.011064 (rank : 131)
Query Neighborhood Hits	150	Target Neighborhood Hits	1040	Shared Neighborhood Hits	28
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

K1683_HUMAN
θ value	3.0926 (rank : 99)	NC score	0.022472 (rank : 95)
Query Neighborhood Hits	150	Target Neighborhood Hits	240	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

KIF3B_HUMAN
θ value	3.0926 (rank : 100)	NC score	0.006372 (rank : 141)
Query Neighborhood Hits	150	Target Neighborhood Hits	540	Shared Neighborhood Hits	13
SwissProt Accessions	O15066	Gene names	KIF3B, KIAA0359
Domain Architecture
Description	Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B) (HH0048).

KIF3B_MOUSE
θ value	3.0926 (rank : 101)	NC score	0.006334 (rank : 142)
Query Neighborhood Hits	150	Target Neighborhood Hits	533	Shared Neighborhood Hits	12
SwissProt Accessions	Q61771	Gene names	Kif3b
Domain Architecture
Description	Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B).

MAST2_HUMAN
θ value	3.0926 (rank : 102)	NC score	-0.000107 (rank : 159)
Query Neighborhood Hits	150	Target Neighborhood Hits	1189	Shared Neighborhood Hits	18
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

PELP1_HUMAN
θ value	3.0926 (rank : 103)	NC score	0.022794 (rank : 94)
Query Neighborhood Hits	150	Target Neighborhood Hits	596	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

PKHB2_HUMAN
θ value	3.0926 (rank : 104)	NC score	0.074336 (rank : 58)
Query Neighborhood Hits	150	Target Neighborhood Hits	54	Shared Neighborhood Hits	32
SwissProt Accessions	Q96CS7, Q86W37, Q9BV75, Q9NWK1	Gene names	PLEKHB2, EVT2
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 2 (Evectin-2).

PKHC1_HUMAN
θ value	3.0926 (rank : 105)	NC score	0.031513 (rank : 83)
Query Neighborhood Hits	150	Target Neighborhood Hits	32	Shared Neighborhood Hits	8
SwissProt Accessions	Q96AC1, Q14840, Q86TY7	Gene names	PLEKHC1, KIND2, MIG2
Domain Architecture
Description	Pleckstrin homology domain-containing family C member 1 (Kindlin-2) (Mitogen-inducible gene 2 protein) (Mig-2).

PKHC1_MOUSE
θ value	3.0926 (rank : 106)	NC score	0.030433 (rank : 85)
Query Neighborhood Hits	150	Target Neighborhood Hits	28	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CIB5, Q8C542, Q8K035	Gene names	Plekhc1
Domain Architecture
Description	Pleckstrin homology domain-containing family C member 1.

TRHY_HUMAN
θ value	3.0926 (rank : 107)	NC score	0.010204 (rank : 134)
Query Neighborhood Hits	150	Target Neighborhood Hits	1385	Shared Neighborhood Hits	25
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

URP2_HUMAN
θ value	3.0926 (rank : 108)	NC score	0.060188 (rank : 70)
Query Neighborhood Hits	150	Target Neighborhood Hits	30	Shared Neighborhood Hits	14
SwissProt Accessions	Q86UX7, Q8IUA1, Q8N207, Q9BT48	Gene names	URP2, KIND3, MIG2B
Domain Architecture
Description	Unc-112-related protein 2 (Kindlin-3) (MIG2-like).

AKT1_MOUSE
θ value	4.03905 (rank : 109)	NC score	0.005908 (rank : 146)
Query Neighborhood Hits	150	Target Neighborhood Hits	878	Shared Neighborhood Hits	35
SwissProt Accessions	P31750, Q62274	Gene names	Akt1, Akt, Rac
Domain Architecture
Description	RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-alpha) (AKT1 kinase) (Protein kinase B) (PKB) (C-AKT) (Thymoma viral proto- oncogene).

K1196_HUMAN
θ value	4.03905 (rank : 110)	NC score	0.005954 (rank : 145)
Query Neighborhood Hits	150	Target Neighborhood Hits	618	Shared Neighborhood Hits	10
SwissProt Accessions	Q96KM6, Q9ULM4	Gene names	KIAA1196
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1196.

NCA11_MOUSE
θ value	4.03905 (rank : 111)	NC score	0.003860 (rank : 152)
Query Neighborhood Hits	150	Target Neighborhood Hits	661	Shared Neighborhood Hits	20
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

SUHW3_MOUSE
θ value	4.03905 (rank : 112)	NC score	-0.000601 (rank : 160)
Query Neighborhood Hits	150	Target Neighborhood Hits	697	Shared Neighborhood Hits	6
SwissProt Accessions	Q6P3Y5, Q6ZPM2, Q8K145	Gene names	Suhw3, Kiaa1584
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 3.

VCX1_HUMAN
θ value	4.03905 (rank : 113)	NC score	0.022002 (rank : 97)
Query Neighborhood Hits	150	Target Neighborhood Hits	129	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H320, Q9P0H3	Gene names	VCX, VCX1, VCX10R, VCXB1
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 1 (VCX-B1 protein) (Variably charged protein X-B1) (Variable charge protein on X with ten repeats) (VCX- 10r).

WDR23_MOUSE
θ value	4.03905 (rank : 114)	NC score	0.005069 (rank : 151)
Query Neighborhood Hits	150	Target Neighborhood Hits	271	Shared Neighborhood Hits	2
SwissProt Accessions	Q91VU6, Q3U836, Q8JZV8	Gene names	Wdr23, D14Ucla1
Domain Architecture
Description	WD repeat protein 23.

WNK1_HUMAN
θ value	4.03905 (rank : 115)	NC score	0.001922 (rank : 156)
Query Neighborhood Hits	150	Target Neighborhood Hits	1158	Shared Neighborhood Hits	22
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

ARNT2_MOUSE
θ value	5.27518 (rank : 116)	NC score	0.006928 (rank : 139)
Query Neighborhood Hits	150	Target Neighborhood Hits	115	Shared Neighborhood Hits	7
SwissProt Accessions	Q61324	Gene names	Arnt2
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

LTBP4_MOUSE
θ value	5.27518 (rank : 117)	NC score	0.001004 (rank : 158)
Query Neighborhood Hits	150	Target Neighborhood Hits	607	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

PKHA1_MOUSE
θ value	5.27518 (rank : 118)	NC score	0.096406 (rank : 41)
Query Neighborhood Hits	150	Target Neighborhood Hits	120	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

TCOF_MOUSE
θ value	5.27518 (rank : 119)	NC score	0.021129 (rank : 98)
Query Neighborhood Hits	150	Target Neighborhood Hits	471	Shared Neighborhood Hits	18
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

TXLNB_HUMAN
θ value	5.27518 (rank : 120)	NC score	0.013530 (rank : 125)
Query Neighborhood Hits	150	Target Neighborhood Hits	912	Shared Neighborhood Hits	32
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

APC_MOUSE
θ value	6.88961 (rank : 121)	NC score	0.015088 (rank : 117)
Query Neighborhood Hits	150	Target Neighborhood Hits	441	Shared Neighborhood Hits	18
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

BAG3_MOUSE
θ value	6.88961 (rank : 122)	NC score	0.013386 (rank : 126)
Query Neighborhood Hits	150	Target Neighborhood Hits	513	Shared Neighborhood Hits	31
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

CAF1A_HUMAN
θ value	6.88961 (rank : 123)	NC score	0.014292 (rank : 119)
Query Neighborhood Hits	150	Target Neighborhood Hits	750	Shared Neighborhood Hits	18
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

FGD4_MOUSE
θ value	6.88961 (rank : 124)	NC score	0.012808 (rank : 129)
Query Neighborhood Hits	150	Target Neighborhood Hits	227	Shared Neighborhood Hits	21
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

FINC_MOUSE
θ value	6.88961 (rank : 125)	NC score	0.001928 (rank : 155)
Query Neighborhood Hits	150	Target Neighborhood Hits	309	Shared Neighborhood Hits	5
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

GAB1_MOUSE
θ value	6.88961 (rank : 126)	NC score	0.055746 (rank : 73)
Query Neighborhood Hits	150	Target Neighborhood Hits	233	Shared Neighborhood Hits	40
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

MARCS_HUMAN
θ value	6.88961 (rank : 127)	NC score	0.013771 (rank : 123)
Query Neighborhood Hits	150	Target Neighborhood Hits	204	Shared Neighborhood Hits	13
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

MEGF8_MOUSE
θ value	6.88961 (rank : 128)	NC score	0.003839 (rank : 153)
Query Neighborhood Hits	150	Target Neighborhood Hits	520	Shared Neighborhood Hits	6
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MYLK_MOUSE
θ value	6.88961 (rank : 129)	NC score	-0.001113 (rank : 162)
Query Neighborhood Hits	150	Target Neighborhood Hits	1489	Shared Neighborhood Hits	30
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

NPAS4_HUMAN
θ value	6.88961 (rank : 130)	NC score	0.013763 (rank : 124)
Query Neighborhood Hits	150	Target Neighborhood Hits	214	Shared Neighborhood Hits	17
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

PAI1_HUMAN
θ value	6.88961 (rank : 131)	NC score	0.001368 (rank : 157)
Query Neighborhood Hits	150	Target Neighborhood Hits	78	Shared Neighborhood Hits	2
SwissProt Accessions	P05121	Gene names	SERPINE1, PAI1, PLANH1
Domain Architecture
Description	Plasminogen activator inhibitor 1 precursor (PAI-1) (Endothelial plasminogen activator inhibitor) (PAI).

PESC_HUMAN
θ value	6.88961 (rank : 132)	NC score	0.009114 (rank : 135)
Query Neighborhood Hits	150	Target Neighborhood Hits	90	Shared Neighborhood Hits	2
SwissProt Accessions	O00541, Q6IC29	Gene names	PES1
Domain Architecture
Description	Pescadillo homolog 1.

PININ_HUMAN
θ value	6.88961 (rank : 133)	NC score	0.014543 (rank : 118)
Query Neighborhood Hits	150	Target Neighborhood Hits	753	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

PLCG1_MOUSE
θ value	6.88961 (rank : 134)	NC score	0.007696 (rank : 137)
Query Neighborhood Hits	150	Target Neighborhood Hits	314	Shared Neighborhood Hits	12
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

RTP3_MOUSE
θ value	6.88961 (rank : 135)	NC score	0.018315 (rank : 103)
Query Neighborhood Hits	150	Target Neighborhood Hits	374	Shared Neighborhood Hits	23
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

SRA1_HUMAN
θ value	6.88961 (rank : 136)	NC score	0.012018 (rank : 130)
Query Neighborhood Hits	150	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HD15, Q6NVU9, Q8IXM1, Q9HD13, Q9HD14	Gene names	SRA1
Domain Architecture	No domain graphic available
Description	Steroid receptor RNA activator 1 (Steroid receptor RNA activator protein) (SRAP).

TCOF_HUMAN
θ value	6.88961 (rank : 137)	NC score	0.016835 (rank : 110)
Query Neighborhood Hits	150	Target Neighborhood Hits	543	Shared Neighborhood Hits	21
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

CEND1_MOUSE
θ value	8.99809 (rank : 138)	NC score	0.048995 (rank : 77)
Query Neighborhood Hits	150	Target Neighborhood Hits	260	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

COFA1_HUMAN
θ value	8.99809 (rank : 139)	NC score	0.007981 (rank : 136)
Query Neighborhood Hits	150	Target Neighborhood Hits	292	Shared Neighborhood Hits	13
SwissProt Accessions	P39059, Q5T6J4, Q9Y4W4	Gene names	COL15A1
Domain Architecture
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV) (Restin) (Related to endostatin)].

DOK2_HUMAN
θ value	8.99809 (rank : 140)	NC score	0.006115 (rank : 144)
Query Neighborhood Hits	150	Target Neighborhood Hits	46	Shared Neighborhood Hits	4
SwissProt Accessions	O60496	Gene names	DOK2
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)).

K0310_HUMAN
θ value	8.99809 (rank : 141)	NC score	0.012964 (rank : 128)
Query Neighborhood Hits	150	Target Neighborhood Hits	420	Shared Neighborhood Hits	23
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

KIFC3_MOUSE
θ value	8.99809 (rank : 142)	NC score	0.006233 (rank : 143)
Query Neighborhood Hits	150	Target Neighborhood Hits	571	Shared Neighborhood Hits	19
SwissProt Accessions	O35231, Q91YQ2	Gene names	Kifc3
Domain Architecture
Description	Kinesin-like protein KIFC3.

KIT_HUMAN
θ value	8.99809 (rank : 143)	NC score	-0.000979 (rank : 161)
Query Neighborhood Hits	150	Target Neighborhood Hits	953	Shared Neighborhood Hits	10
SwissProt Accessions	P10721, Q9UM99	Gene names	KIT
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

MAGC1_HUMAN
θ value	8.99809 (rank : 144)	NC score	0.007329 (rank : 138)
Query Neighborhood Hits	150	Target Neighborhood Hits	431	Shared Neighborhood Hits	23
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

MEGF8_HUMAN
θ value	8.99809 (rank : 145)	NC score	0.003401 (rank : 154)
Query Neighborhood Hits	150	Target Neighborhood Hits	528	Shared Neighborhood Hits	5
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

PININ_MOUSE
θ value	8.99809 (rank : 146)	NC score	0.016823 (rank : 111)
Query Neighborhood Hits	150	Target Neighborhood Hits	777	Shared Neighborhood Hits	22
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

SRRM2_MOUSE
θ value	8.99809 (rank : 147)	NC score	0.018301 (rank : 104)
Query Neighborhood Hits	150	Target Neighborhood Hits	1470	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

SYN3_HUMAN
θ value	8.99809 (rank : 148)	NC score	0.006578 (rank : 140)
Query Neighborhood Hits	150	Target Neighborhood Hits	203	Shared Neighborhood Hits	13
SwissProt Accessions	O14994	Gene names	SYN3
Domain Architecture
Description	Synapsin-3 (Synapsin III).

TB182_HUMAN
θ value	8.99809 (rank : 149)	NC score	0.014127 (rank : 121)
Query Neighborhood Hits	150	Target Neighborhood Hits	414	Shared Neighborhood Hits	16
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

ZN219_HUMAN
θ value	8.99809 (rank : 150)	NC score	-0.003186 (rank : 163)
Query Neighborhood Hits	150	Target Neighborhood Hits	876	Shared Neighborhood Hits	11
SwissProt Accessions	Q9P2Y4, Q8IYC1, Q9BW28	Gene names	ZNF219
Domain Architecture	No domain graphic available
Description	Zinc finger protein 219.

CENB1_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.056850 (rank : 72)
Query Neighborhood Hits	150	Target Neighborhood Hits	383	Shared Neighborhood Hits	46
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

CENB5_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.055098 (rank : 75)
Query Neighborhood Hits	150	Target Neighborhood Hits	395	Shared Neighborhood Hits	50
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

CYH1_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.066833 (rank : 64)
Query Neighborhood Hits	150	Target Neighborhood Hits	184	Shared Neighborhood Hits	52
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

CYH1_MOUSE
θ value	θ > 10 (rank : 154)	NC score	0.064689 (rank : 67)
Query Neighborhood Hits	150	Target Neighborhood Hits	176	Shared Neighborhood Hits	49
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

CYH2_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.065054 (rank : 66)
Query Neighborhood Hits	150	Target Neighborhood Hits	175	Shared Neighborhood Hits	47
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

CYH2_MOUSE
θ value	θ > 10 (rank : 156)	NC score	0.065067 (rank : 65)
Query Neighborhood Hits	150	Target Neighborhood Hits	171	Shared Neighborhood Hits	47
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

CYH3_HUMAN
θ value	θ > 10 (rank : 157)	NC score	0.062431 (rank : 68)
Query Neighborhood Hits	150	Target Neighborhood Hits	137	Shared Neighborhood Hits	45
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

DDFL1_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.059766 (rank : 71)
Query Neighborhood Hits	150	Target Neighborhood Hits	353	Shared Neighborhood Hits	33
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

DDFL1_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.062052 (rank : 69)
Query Neighborhood Hits	150	Target Neighborhood Hits	324	Shared Neighborhood Hits	25
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

GAB1_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.055388 (rank : 74)
Query Neighborhood Hits	150	Target Neighborhood Hits	279	Shared Neighborhood Hits	42
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

PLEK_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.082028 (rank : 54)
Query Neighborhood Hits	150	Target Neighborhood Hits	110	Shared Neighborhood Hits	41
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

PLEK_MOUSE
θ value	θ > 10 (rank : 162)	NC score	0.083577 (rank : 50)
Query Neighborhood Hits	150	Target Neighborhood Hits	109	Shared Neighborhood Hits	40
SwissProt Accessions	Q9JHK5, Q9ERI9	Gene names	Plek
Domain Architecture
Description	Pleckstrin.

TBCD2_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.051033 (rank : 76)
Query Neighborhood Hits	150	Target Neighborhood Hits	419	Shared Neighborhood Hits	44
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

Hits sorted by NC score

OSBP2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	150	Target Neighborhood Hits	150	Shared Neighborhood Hits	150
SwissProt Accessions	Q5QNQ6, Q8CF21	Gene names	Osbp2
Domain Architecture	No domain graphic available
Description	Oxysterol-binding protein 2.

OSBP2_HUMAN
NC score	0.985261 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	150	Target Neighborhood Hits	154	Shared Neighborhood Hits	72
SwissProt Accessions	Q969R2, O60396, Q9BY96, Q9BZF0	Gene names	OSBP2, KIAA1664, ORP4, OSBPL4
Domain Architecture
Description	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).

OSBP1_HUMAN
NC score	0.972015 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	150	Target Neighborhood Hits	180	Shared Neighborhood Hits	69
SwissProt Accessions	P22059	Gene names	OSBP, OSBP1
Domain Architecture
Description	Oxysterol-binding protein 1.

OSBL2_HUMAN
NC score	0.907733 (rank : 4)	θ value	7.20884e-74 (rank : 7)
Query Neighborhood Hits	150	Target Neighborhood Hits	23	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H1P3, Q9BZB1, Q9Y4B8	Gene names	OSBPL2, KIAA0772, ORP2
Domain Architecture
Description	Oxysterol-binding protein-related protein 2 (OSBP-related protein 2) (ORP-2).

OSBL2_MOUSE
NC score	0.907485 (rank : 5)	θ value	1.35953e-72 (rank : 9)
Query Neighborhood Hits	150	Target Neighborhood Hits	22	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BX94, Q3TCK8, Q8R0H8	Gene names	Osbpl2
Domain Architecture
Description	Oxysterol-binding protein-related protein 2 (OSBP-related protein 2) (ORP-2).

OSBL7_HUMAN
NC score	0.901147 (rank : 6)	θ value	5.53243e-66 (rank : 12)
Query Neighborhood Hits	150	Target Neighborhood Hits	71	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BZF2	Gene names	OSBPL7, ORP7
Domain Architecture
Description	Oxysterol-binding protein-related protein 7 (OSBP-related protein 7) (ORP-7).

OSBL3_MOUSE
NC score	0.895243 (rank : 7)	θ value	5.71191e-71 (rank : 10)
Query Neighborhood Hits	150	Target Neighborhood Hits	86	Shared Neighborhood Hits	45
SwissProt Accessions	Q9DBS9	Gene names	Osbpl3, Orp3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

OSBL3_HUMAN
NC score	0.892414 (rank : 8)	θ value	1.66191e-70 (rank : 11)
Query Neighborhood Hits	150	Target Neighborhood Hits	93	Shared Neighborhood Hits	45
SwissProt Accessions	Q9H4L5, O14591, O43357, O43358, Q8N702, Q8N703, Q8N704, Q8NFH0, Q8NFH1, Q8NI12, Q8NI13, Q9BZF4, Q9UED6	Gene names	OSBPL3, KIAA0704, ORP3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

OSBL6_HUMAN
NC score	0.890323 (rank : 9)	θ value	3.23591e-74 (rank : 6)
Query Neighborhood Hits	150	Target Neighborhood Hits	101	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BZF3, Q7Z4Q1, Q96SR1	Gene names	OSBPL6, ORP6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

OSBL6_MOUSE
NC score	0.888600 (rank : 10)	θ value	3.57772e-73 (rank : 8)
Query Neighborhood Hits	150	Target Neighborhood Hits	105	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BXR9, Q8BYW2	Gene names	Osbpl6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

OSBL5_HUMAN
NC score	0.683419 (rank : 11)	θ value	5.42112e-21 (rank : 13)
Query Neighborhood Hits	150	Target Neighborhood Hits	117	Shared Neighborhood Hits	28
SwissProt Accessions	Q9H0X9, Q9BZB0, Q9P1Z4	Gene names	OSBPL5, KIAA1534, ORP5
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5).

OSBL5_MOUSE
NC score	0.678707 (rank : 12)	θ value	2.5182e-18 (rank : 14)
Query Neighborhood Hits	150	Target Neighborhood Hits	77	Shared Neighborhood Hits	27
SwissProt Accessions	Q9ER64, Q8R510, Q99NF5	Gene names	Osbpl5, Obph1, Osbp2
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5) (Oxysterol-binding protein homolog 1).

OSBL9_HUMAN
NC score	0.673269 (rank : 13)	θ value	6.21693e-09 (rank : 23)
Query Neighborhood Hits	150	Target Neighborhood Hits	138	Shared Neighborhood Hits	52
SwissProt Accessions	Q96SU4, Q9H9X2	Gene names	OSBPL9, ORP9, OSBP4
Domain Architecture
Description	Oxysterol-binding protein-related protein 9 (OSBP-related protein 9) (ORP-9).

OSB10_HUMAN
NC score	0.666123 (rank : 14)	θ value	7.84624e-12 (rank : 20)
Query Neighborhood Hits	150	Target Neighborhood Hits	55	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BXB5, Q9BTU5	Gene names	OSBPL10, ORP10, OSBP9
Domain Architecture
Description	Oxysterol-binding protein-related protein 10 (OSBP-related protein 10) (ORP-10).

OSBL8_HUMAN
NC score	0.664424 (rank : 15)	θ value	3.28887e-18 (rank : 15)
Query Neighborhood Hits	150	Target Neighborhood Hits	289	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

OSB11_MOUSE
NC score	0.661808 (rank : 16)	θ value	1.80466e-16 (rank : 16)
Query Neighborhood Hits	150	Target Neighborhood Hits	71	Shared Neighborhood Hits	36
SwissProt Accessions	Q8CI95	Gene names	Osbpl11
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

OSB11_HUMAN
NC score	0.651702 (rank : 17)	θ value	7.58209e-15 (rank : 18)
Query Neighborhood Hits	150	Target Neighborhood Hits	60	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BXB4	Gene names	OSBPL11, ORP11, OSBP12
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

OSBL1_MOUSE
NC score	0.641164 (rank : 18)	θ value	1.82896e-85 (rank : 4)
Query Neighborhood Hits	150	Target Neighborhood Hits	336	Shared Neighborhood Hits	32
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

OSBL1_HUMAN
NC score	0.626172 (rank : 19)	θ value	2.38869e-85 (rank : 5)
Query Neighborhood Hits	150	Target Neighborhood Hits	368	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

PKHA3_MOUSE
NC score	0.538893 (rank : 20)	θ value	1.99529e-15 (rank : 17)
Query Neighborhood Hits	150	Target Neighborhood Hits	67	Shared Neighborhood Hits	43
SwissProt Accessions	Q9ERS4	Gene names	Plekha3, Fapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

PKHA3_HUMAN
NC score	0.519765 (rank : 21)	θ value	1.2105e-12 (rank : 19)
Query Neighborhood Hits	150	Target Neighborhood Hits	66	Shared Neighborhood Hits	43
SwissProt Accessions	Q9HB20, Q86TQ1, Q9NXT3	Gene names	PLEKHA3, FAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

C43BP_HUMAN
NC score	0.462692 (rank : 22)	θ value	5.08577e-11 (rank : 21)
Query Neighborhood Hits	150	Target Neighborhood Hits	87	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y5P4, Q96Q85, Q96Q88, Q9H2S7, Q9H2S8	Gene names	COL4A3BP, STARD11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

C43BP_MOUSE
NC score	0.459368 (rank : 23)	θ value	5.08577e-11 (rank : 22)
Query Neighborhood Hits	150	Target Neighborhood Hits	91	Shared Neighborhood Hits	52
SwissProt Accessions	Q9EQG9, Q91WB1, Q9CU52, Q9EQG8	Gene names	Col4a3bp, Stard11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

PKHA6_HUMAN
NC score	0.147643 (rank : 24)	θ value	0.00869519 (rank : 29)
Query Neighborhood Hits	150	Target Neighborhood Hits	556	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA6_MOUSE
NC score	0.138585 (rank : 25)	θ value	0.0431538 (rank : 31)
Query Neighborhood Hits	150	Target Neighborhood Hits	591	Shared Neighborhood Hits	64
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA2_MOUSE
NC score	0.117691 (rank : 26)	θ value	0.0330416 (rank : 30)
Query Neighborhood Hits	150	Target Neighborhood Hits	116	Shared Neighborhood Hits	48
SwissProt Accessions	Q9ERS5, Q8BY29	Gene names	Plekha2, Tapp2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2) (PH domain-containing adaptor PHAD47).

PKHA4_HUMAN
NC score	0.116601 (rank : 27)	θ value	0.0961366 (rank : 36)
Query Neighborhood Hits	150	Target Neighborhood Hits	283	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

DDEF1_MOUSE
NC score	0.115550 (rank : 28)	θ value	0.00869519 (rank : 28)
Query Neighborhood Hits	150	Target Neighborhood Hits	592	Shared Neighborhood Hits	39
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

PKHB1_MOUSE
NC score	0.111993 (rank : 29)	θ value	0.21417 (rank : 42)
Query Neighborhood Hits	150	Target Neighborhood Hits	47	Shared Neighborhood Hits	32
SwissProt Accessions	Q9QYE9, Q9QYB3, Q9QYB4, Q9QYD2, Q9QYD3	Gene names	Plekhb1, Phr1
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 1 (Pleckstrin homology domain retinal protein 1) (PH domain-containing protein in retina 1) (PHRET1).

PKHA2_HUMAN
NC score	0.110348 (rank : 30)	θ value	0.365318 (rank : 47)
Query Neighborhood Hits	150	Target Neighborhood Hits	119	Shared Neighborhood Hits	47
SwissProt Accessions	Q9HB19	Gene names	PLEKHA2, TAPP2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2).

PLEK2_MOUSE
NC score	0.110032 (rank : 31)	θ value	1.81305 (rank : 91)
Query Neighborhood Hits	150	Target Neighborhood Hits	96	Shared Neighborhood Hits	41
SwissProt Accessions	Q9WV52	Gene names	Plek2
Domain Architecture
Description	Pleckstrin-2.

PKHA4_MOUSE
NC score	0.109662 (rank : 32)	θ value	0.279714 (rank : 45)
Query Neighborhood Hits	150	Target Neighborhood Hits	202	Shared Neighborhood Hits	44
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PLEK2_HUMAN
NC score	0.109535 (rank : 33)	θ value	2.36792 (rank : 94)
Query Neighborhood Hits	150	Target Neighborhood Hits	101	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

SWP70_HUMAN
NC score	0.109216 (rank : 34)	θ value	0.365318 (rank : 49)
Query Neighborhood Hits	150	Target Neighborhood Hits	973	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

PKHB1_HUMAN
NC score	0.109183 (rank : 35)	θ value	0.365318 (rank : 48)
Query Neighborhood Hits	150	Target Neighborhood Hits	46	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UF11, Q9UBF5, Q9UI37, Q9UI44	Gene names	PLEKHB1, KPL1, PHR1
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 1 (Pleckstrin homology domain retinal protein 1) (PH domain-containing protein in retina 1) (PHRET1).

GAB2_MOUSE
NC score	0.105862 (rank : 36)	θ value	0.125558 (rank : 38)
Query Neighborhood Hits	150	Target Neighborhood Hits	220	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

SWP70_MOUSE
NC score	0.105374 (rank : 37)	θ value	0.279714 (rank : 46)
Query Neighborhood Hits	150	Target Neighborhood Hits	1097	Shared Neighborhood Hits	80
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

PKHA1_HUMAN
NC score	0.103800 (rank : 38)	θ value	0.62314 (rank : 59)
Query Neighborhood Hits	150	Target Neighborhood Hits	127	Shared Neighborhood Hits	48
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

TARA_MOUSE
NC score	0.103674 (rank : 39)	θ value	0.00665767 (rank : 26)
Query Neighborhood Hits	150	Target Neighborhood Hits	1133	Shared Neighborhood Hits	74
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

PKHA5_HUMAN
NC score	0.099615 (rank : 40)	θ value	1.38821 (rank : 77)
Query Neighborhood Hits	150	Target Neighborhood Hits	455	Shared Neighborhood Hits	57
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

PKHA1_MOUSE
NC score	0.096406 (rank : 41)	θ value	5.27518 (rank : 118)
Query Neighborhood Hits	150	Target Neighborhood Hits	120	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

RHG25_MOUSE
NC score	0.095471 (rank : 42)	θ value	0.163984 (rank : 41)
Query Neighborhood Hits	150	Target Neighborhood Hits	492	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

CYH4_MOUSE
NC score	0.095071 (rank : 43)	θ value	0.47712 (rank : 53)
Query Neighborhood Hits	150	Target Neighborhood Hits	134	Shared Neighborhood Hits	49
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

RHG25_HUMAN
NC score	0.094311 (rank : 44)	θ value	0.62314 (rank : 60)
Query Neighborhood Hits	150	Target Neighborhood Hits	550	Shared Neighborhood Hits	64
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

CYH4_HUMAN
NC score	0.093902 (rank : 45)	θ value	0.47712 (rank : 52)
Query Neighborhood Hits	150	Target Neighborhood Hits	135	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UIA0, Q5R3F9, Q9UGT6	Gene names	PSCD4, CYT4
Domain Architecture
Description	Cytohesin-4.

MTMRD_HUMAN
NC score	0.092451 (rank : 46)	θ value	0.813845 (rank : 65)
Query Neighborhood Hits	150	Target Neighborhood Hits	135	Shared Neighborhood Hits	46
SwissProt Accessions	Q86WG5, Q3MJF0, Q68DQ3, Q6P459, Q6PJD1, Q7Z325, Q7Z621, Q86VE2, Q96FE2, Q9C097	Gene names	SBF2, CMT4B2, KIAA1766, MTMR13
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 13 (SET-binding factor 2).

GAB2_HUMAN
NC score	0.091808 (rank : 47)	θ value	0.62314 (rank : 58)
Query Neighborhood Hits	150	Target Neighborhood Hits	188	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UQC2, O60317	Gene names	GAB2, KIAA0571
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (pp100).

MRIP_MOUSE
NC score	0.090001 (rank : 48)	θ value	0.0563607 (rank : 32)
Query Neighborhood Hits	150	Target Neighborhood Hits	569	Shared Neighborhood Hits	51
SwissProt Accessions	P97434, Q3TBR5, Q3TC85, Q3TRS0, Q3U1Y8, Q3U3E4, Q5SWZ3, Q5SWZ4, Q5SWZ7, Q6P559, Q80YC8	Gene names	Mrip, Kiaa0864, Rhoip3
Domain Architecture
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (p116Rip) (RIP3).

DAPP1_MOUSE
NC score	0.086606 (rank : 49)	θ value	0.125558 (rank : 37)
Query Neighborhood Hits	150	Target Neighborhood Hits	225	Shared Neighborhood Hits	49
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

PLEK_MOUSE
NC score	0.083577 (rank : 50)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	150	Target Neighborhood Hits	109	Shared Neighborhood Hits	40
SwissProt Accessions	Q9JHK5, Q9ERI9	Gene names	Plek
Domain Architecture
Description	Pleckstrin.

DDEF2_HUMAN
NC score	0.083483 (rank : 51)	θ value	0.0961366 (rank : 34)
Query Neighborhood Hits	150	Target Neighborhood Hits	599	Shared Neighborhood Hits	39
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
NC score	0.082877 (rank : 52)	θ value	0.0961366 (rank : 35)
Query Neighborhood Hits	150	Target Neighborhood Hits	625	Shared Neighborhood Hits	38
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

MRIP_HUMAN
NC score	0.082294 (rank : 53)	θ value	0.163984 (rank : 40)
Query Neighborhood Hits	150	Target Neighborhood Hits	578	Shared Neighborhood Hits	56
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

PLEK_HUMAN
NC score	0.082028 (rank : 54)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	150	Target Neighborhood Hits	110	Shared Neighborhood Hits	41
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

PKHB2_MOUSE
NC score	0.081276 (rank : 55)	θ value	1.38821 (rank : 78)
Query Neighborhood Hits	150	Target Neighborhood Hits	48	Shared Neighborhood Hits	29
SwissProt Accessions	Q9QZC7, Q3UDH6, Q8C4I4, Q8CA27	Gene names	Plekhb2, Evt2
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 2 (Evectin-2).

CYH3_MOUSE
NC score	0.080951 (rank : 56)	θ value	0.47712 (rank : 51)
Query Neighborhood Hits	150	Target Neighborhood Hits	148	Shared Neighborhood Hits	51
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

DAPP1_HUMAN
NC score	0.075737 (rank : 57)	θ value	0.62314 (rank : 56)
Query Neighborhood Hits	150	Target Neighborhood Hits	227	Shared Neighborhood Hits	48
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

PKHB2_HUMAN
NC score	0.074336 (rank : 58)	θ value	3.0926 (rank : 104)
Query Neighborhood Hits	150	Target Neighborhood Hits	54	Shared Neighborhood Hits	32
SwissProt Accessions	Q96CS7, Q86W37, Q9BV75, Q9NWK1	Gene names	PLEKHB2, EVT2
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 2 (Evectin-2).

URP2_MOUSE
NC score	0.071971 (rank : 59)	θ value	0.813845 (rank : 67)
Query Neighborhood Hits	150	Target Neighborhood Hits	37	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K1B8	Gene names	Urp2, Kind3
Domain Architecture
Description	Unc-112-related protein 2 (Kindlin-3).

CEND2_HUMAN
NC score	0.070578 (rank : 60)	θ value	0.0736092 (rank : 33)
Query Neighborhood Hits	150	Target Neighborhood Hits	166	Shared Neighborhood Hits	39
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

TARA_HUMAN
NC score	0.069115 (rank : 61)	θ value	0.365318 (rank : 50)
Query Neighborhood Hits	150	Target Neighborhood Hits	1626	Shared Neighborhood Hits	82
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

MYO10_HUMAN
NC score	0.068575 (rank : 62)	θ value	0.00175202 (rank : 24)
Query Neighborhood Hits	150	Target Neighborhood Hits	920	Shared Neighborhood Hits	76
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

CEND1_HUMAN
NC score	0.067399 (rank : 63)	θ value	0.813845 (rank : 61)
Query Neighborhood Hits	150	Target Neighborhood Hits	284	Shared Neighborhood Hits	49
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

CYH1_HUMAN
NC score	0.066833 (rank : 64)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	150	Target Neighborhood Hits	184	Shared Neighborhood Hits	52
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

CYH2_MOUSE
NC score	0.065067 (rank : 65)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	150	Target Neighborhood Hits	171	Shared Neighborhood Hits	47
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

CYH2_HUMAN
NC score	0.065054 (rank : 66)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	150	Target Neighborhood Hits	175	Shared Neighborhood Hits	47
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

CYH1_MOUSE
NC score	0.064689 (rank : 67)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	150	Target Neighborhood Hits	176	Shared Neighborhood Hits	49
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

CYH3_HUMAN
NC score	0.062431 (rank : 68)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	150	Target Neighborhood Hits	137	Shared Neighborhood Hits	45
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

DDFL1_MOUSE
NC score	0.062052 (rank : 69)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	150	Target Neighborhood Hits	324	Shared Neighborhood Hits	25
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

URP2_HUMAN
NC score	0.060188 (rank : 70)	θ value	3.0926 (rank : 108)
Query Neighborhood Hits	150	Target Neighborhood Hits	30	Shared Neighborhood Hits	14
SwissProt Accessions	Q86UX7, Q8IUA1, Q8N207, Q9BT48	Gene names	URP2, KIND3, MIG2B
Domain Architecture
Description	Unc-112-related protein 2 (Kindlin-3) (MIG2-like).

DDFL1_HUMAN
NC score	0.059766 (rank : 71)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	150	Target Neighborhood Hits	353	Shared Neighborhood Hits	33
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

CENB1_HUMAN
NC score	0.056850 (rank : 72)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	150	Target Neighborhood Hits	383	Shared Neighborhood Hits	46
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

GAB1_MOUSE
NC score	0.055746 (rank : 73)	θ value	6.88961 (rank : 126)
Query Neighborhood Hits	150	Target Neighborhood Hits	233	Shared Neighborhood Hits	40
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

GAB1_HUMAN
NC score	0.055388 (rank : 74)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	150	Target Neighborhood Hits	279	Shared Neighborhood Hits	42
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

CENB5_HUMAN
NC score	0.055098 (rank : 75)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	150	Target Neighborhood Hits	395	Shared Neighborhood Hits	50
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

TBCD2_HUMAN
NC score	0.051033 (rank : 76)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	150	Target Neighborhood Hits	419	Shared Neighborhood Hits	44
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

CEND1_MOUSE
NC score	0.048995 (rank : 77)	θ value	8.99809 (rank : 138)
Query Neighborhood Hits	150	Target Neighborhood Hits	260	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

DREB_MOUSE
NC score	0.044056 (rank : 78)	θ value	0.62314 (rank : 57)
Query Neighborhood Hits	150	Target Neighborhood Hits	446	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QXS6, Q922X1, Q9QXS5	Gene names	Dbn1, Drba
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

DREB_HUMAN
NC score	0.041285 (rank : 79)	θ value	0.813845 (rank : 62)
Query Neighborhood Hits	150	Target Neighborhood Hits	450	Shared Neighborhood Hits	15
SwissProt Accessions	Q16643	Gene names	DBN1
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

DGKK_HUMAN
NC score	0.037706 (rank : 80)	θ value	0.00298849 (rank : 25)
Query Neighborhood Hits	150	Target Neighborhood Hits	378	Shared Neighborhood Hits	23
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

DOCK9_HUMAN
NC score	0.032686 (rank : 81)	θ value	1.06291 (rank : 70)
Query Neighborhood Hits	150	Target Neighborhood Hits	82	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BZ29, Q5JUD4, Q5JUD6, Q5T2Q1, Q5TAN8, Q9BZ25, Q9BZ26, Q9BZ27, Q9BZ28, Q9UPU4	Gene names	DOCK9, KIAA1058
Domain Architecture
Description	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin 1).

FARP1_HUMAN
NC score	0.031903 (rank : 82)	θ value	1.38821 (rank : 76)
Query Neighborhood Hits	150	Target Neighborhood Hits	241	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

PKHC1_HUMAN
NC score	0.031513 (rank : 83)	θ value	3.0926 (rank : 105)
Query Neighborhood Hits	150	Target Neighborhood Hits	32	Shared Neighborhood Hits	8
SwissProt Accessions	Q96AC1, Q14840, Q86TY7	Gene names	PLEKHC1, KIND2, MIG2
Domain Architecture
Description	Pleckstrin homology domain-containing family C member 1 (Kindlin-2) (Mitogen-inducible gene 2 protein) (Mig-2).

MDC1_MOUSE
NC score	0.030710 (rank : 84)	θ value	0.163984 (rank : 39)
Query Neighborhood Hits	150	Target Neighborhood Hits	998	Shared Neighborhood Hits	49
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

PKHC1_MOUSE
NC score	0.030433 (rank : 85)	θ value	3.0926 (rank : 106)
Query Neighborhood Hits	150	Target Neighborhood Hits	28	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CIB5, Q8C542, Q8K035	Gene names	Plekhc1
Domain Architecture
Description	Pleckstrin homology domain-containing family C member 1.

SGIP1_MOUSE
NC score	0.028513 (rank : 86)	θ value	0.47712 (rank : 54)
Query Neighborhood Hits	150	Target Neighborhood Hits	180	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

BSN_MOUSE
NC score	0.027098 (rank : 87)	θ value	1.81305 (rank : 85)
Query Neighborhood Hits	150	Target Neighborhood Hits	2057	Shared Neighborhood Hits	69
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

RASA2_MOUSE
NC score	0.026149 (rank : 88)	θ value	1.06291 (rank : 72)
Query Neighborhood Hits	150	Target Neighborhood Hits	159	Shared Neighborhood Hits	24
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

VITRN_HUMAN
NC score	0.025918 (rank : 89)	θ value	0.00665767 (rank : 27)
Query Neighborhood Hits	150	Target Neighborhood Hits	63	Shared Neighborhood Hits	2
SwissProt Accessions	Q6UXI7, Q6P7T3, Q96DT1	Gene names	VIT
Domain Architecture	No domain graphic available
Description	Vitrin precursor.

MAP1A_HUMAN
NC score	0.024624 (rank : 90)	θ value	0.279714 (rank : 44)
Query Neighborhood Hits	150	Target Neighborhood Hits	1626	Shared Neighborhood Hits	47
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

BSN_HUMAN
NC score	0.024617 (rank : 91)	θ value	1.06291 (rank : 69)
Query Neighborhood Hits	150	Target Neighborhood Hits	1537	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

PXK_HUMAN
NC score	0.024146 (rank : 92)	θ value	1.38821 (rank : 79)
Query Neighborhood Hits	150	Target Neighborhood Hits	216	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z7A4, Q3BCH4, Q3BCH5, Q3BCH6, Q3BDW1, Q45L83, Q59EX3, Q6PK17, Q6ZN39, Q96CA3, Q96R07, Q9NXB8	Gene names	PXK
Domain Architecture	No domain graphic available
Description	PX domain-containing protein kinase-like protein (Modulator of Na,K- ATPase) (MONaKA).

SNCAP_HUMAN
NC score	0.022822 (rank : 93)	θ value	1.38821 (rank : 83)
Query Neighborhood Hits	150	Target Neighborhood Hits	313	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y6H5	Gene names	SNCAIP
Domain Architecture
Description	Synphilin-1 (Alpha-synuclein-interacting protein).

PELP1_HUMAN
NC score	0.022794 (rank : 94)	θ value	3.0926 (rank : 103)
Query Neighborhood Hits	150	Target Neighborhood Hits	596	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

K1683_HUMAN
NC score	0.022472 (rank : 95)	θ value	3.0926 (rank : 99)
Query Neighborhood Hits	150	Target Neighborhood Hits	240	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

PXK_MOUSE
NC score	0.022017 (rank : 96)	θ value	2.36792 (rank : 95)
Query Neighborhood Hits	150	Target Neighborhood Hits	320	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BX57, Q3TD60, Q3TEL7, Q3TZZ1, Q3U197, Q3U773, Q3UCS5, Q4FBH7, Q91WB6	Gene names	Pxk
Domain Architecture	No domain graphic available
Description	PX domain-containing protein kinase-like protein (Modulator of Na,K- ATPase) (MONaKA).

VCX1_HUMAN
NC score	0.022002 (rank : 97)	θ value	4.03905 (rank : 113)
Query Neighborhood Hits	150	Target Neighborhood Hits	129	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H320, Q9P0H3	Gene names	VCX, VCX1, VCX10R, VCXB1
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 1 (VCX-B1 protein) (Variably charged protein X-B1) (Variable charge protein on X with ten repeats) (VCX- 10r).

TCOF_MOUSE
NC score	0.021129 (rank : 98)	θ value	5.27518 (rank : 119)
Query Neighborhood Hits	150	Target Neighborhood Hits	471	Shared Neighborhood Hits	18
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

RD23B_MOUSE
NC score	0.020578 (rank : 99)	θ value	1.38821 (rank : 80)
Query Neighborhood Hits	150	Target Neighborhood Hits	189	Shared Neighborhood Hits	14
SwissProt Accessions	P54728	Gene names	Rad23b, Mhr23b
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (mHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

BAT3_HUMAN
NC score	0.019834 (rank : 100)	θ value	1.81305 (rank : 84)
Query Neighborhood Hits	150	Target Neighborhood Hits	490	Shared Neighborhood Hits	20
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

TPR_HUMAN
NC score	0.019680 (rank : 101)	θ value	0.813845 (rank : 66)
Query Neighborhood Hits	150	Target Neighborhood Hits	1921	Shared Neighborhood Hits	51
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

MLL2_HUMAN
NC score	0.019220 (rank : 102)	θ value	0.813845 (rank : 64)
Query Neighborhood Hits	150	Target Neighborhood Hits	1788	Shared Neighborhood Hits	50
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

RTP3_MOUSE
NC score	0.018315 (rank : 103)	θ value	6.88961 (rank : 135)
Query Neighborhood Hits	150	Target Neighborhood Hits	374	Shared Neighborhood Hits	23
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

SRRM2_MOUSE
NC score	0.018301 (rank : 104)	θ value	8.99809 (rank : 147)
Query Neighborhood Hits	150	Target Neighborhood Hits	1470	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

RBP24_HUMAN
NC score	0.017734 (rank : 105)	θ value	1.81305 (rank : 92)
Query Neighborhood Hits	150	Target Neighborhood Hits	1559	Shared Neighborhood Hits	40
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

GCC2_HUMAN
NC score	0.017703 (rank : 106)	θ value	1.81305 (rank : 88)
Query Neighborhood Hits	150	Target Neighborhood Hits	1558	Shared Neighborhood Hits	40
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

ENAH_MOUSE
NC score	0.017416 (rank : 107)	θ value	1.81305 (rank : 87)
Query Neighborhood Hits	150	Target Neighborhood Hits	919	Shared Neighborhood Hits	35
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

RP1L1_HUMAN
NC score	0.017235 (rank : 108)	θ value	1.38821 (rank : 82)
Query Neighborhood Hits	150	Target Neighborhood Hits	1072	Shared Neighborhood Hits	33
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

GCC2_MOUSE
NC score	0.017117 (rank : 109)	θ value	0.813845 (rank : 63)
Query Neighborhood Hits	150	Target Neighborhood Hits	1619	Shared Neighborhood Hits	43
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

TCOF_HUMAN
NC score	0.016835 (rank : 110)	θ value	6.88961 (rank : 137)
Query Neighborhood Hits	150	Target Neighborhood Hits	543	Shared Neighborhood Hits	21
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

PININ_MOUSE
NC score	0.016823 (rank : 111)	θ value	8.99809 (rank : 146)
Query Neighborhood Hits	150	Target Neighborhood Hits	777	Shared Neighborhood Hits	22
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

NCOR1_MOUSE
NC score	0.016542 (rank : 112)	θ value	1.81305 (rank : 90)
Query Neighborhood Hits	150	Target Neighborhood Hits	521	Shared Neighborhood Hits	27
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

K0082_HUMAN
NC score	0.016438 (rank : 113)	θ value	1.81305 (rank : 89)
Query Neighborhood Hits	150	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N1G2, Q14670, Q96FJ9	Gene names	KIAA0082
Domain Architecture	No domain graphic available
Description	Protein KIAA0082.

RERE_MOUSE
NC score	0.016240 (rank : 114)	θ value	1.38821 (rank : 81)
Query Neighborhood Hits	150	Target Neighborhood Hits	785	Shared Neighborhood Hits	28
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

ZN318_HUMAN
NC score	0.016184 (rank : 115)	θ value	2.36792 (rank : 96)
Query Neighborhood Hits	150	Target Neighborhood Hits	497	Shared Neighborhood Hits	16
SwissProt Accessions	Q5VUA4, O94796, Q4G0E4, Q8NEM6, Q9UNU8, Q9Y2W9	Gene names	ZNF318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Endocrine regulatory protein).

AFF2_HUMAN
NC score	0.016011 (rank : 116)	θ value	1.38821 (rank : 74)
Query Neighborhood Hits	150	Target Neighborhood Hits	218	Shared Neighborhood Hits	14
SwissProt Accessions	P51816, O43786, O60215, P78407, Q13521, Q14323, Q9UNA5	Gene names	AFF2, FMR2, OX19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation 2 protein) (Protein FMR-2) (FMR2P) (Protein Ox19) (Fragile X E mental retardation syndrome protein).

APC_MOUSE
NC score	0.015088 (rank : 117)	θ value	6.88961 (rank : 121)
Query Neighborhood Hits	150	Target Neighborhood Hits	441	Shared Neighborhood Hits	18
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

PININ_HUMAN
NC score	0.014543 (rank : 118)	θ value	6.88961 (rank : 133)
Query Neighborhood Hits	150	Target Neighborhood Hits	753	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

CAF1A_HUMAN
NC score	0.014292 (rank : 119)	θ value	6.88961 (rank : 123)
Query Neighborhood Hits	150	Target Neighborhood Hits	750	Shared Neighborhood Hits	18
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

ATX7_MOUSE
NC score	0.014133 (rank : 120)	θ value	3.0926 (rank : 97)
Query Neighborhood Hits	150	Target Neighborhood Hits	328	Shared Neighborhood Hits	9
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

TB182_HUMAN
NC score	0.014127 (rank : 121)	θ value	8.99809 (rank : 149)
Query Neighborhood Hits	150	Target Neighborhood Hits	414	Shared Neighborhood Hits	16
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

CUTL2_MOUSE
NC score	0.013961 (rank : 122)	θ value	1.81305 (rank : 86)
Query Neighborhood Hits	150	Target Neighborhood Hits	771	Shared Neighborhood Hits	25
SwissProt Accessions	P70298	Gene names	Cutl2
Domain Architecture
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

MARCS_HUMAN
NC score	0.013771 (rank : 123)	θ value	6.88961 (rank : 127)
Query Neighborhood Hits	150	Target Neighborhood Hits	204	Shared Neighborhood Hits	13
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

NPAS4_HUMAN
NC score	0.013763 (rank : 124)	θ value	6.88961 (rank : 130)
Query Neighborhood Hits	150	Target Neighborhood Hits	214	Shared Neighborhood Hits	17
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

TXLNB_HUMAN
NC score	0.013530 (rank : 125)	θ value	5.27518 (rank : 120)
Query Neighborhood Hits	150	Target Neighborhood Hits	912	Shared Neighborhood Hits	32
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

BAG3_MOUSE
NC score	0.013386 (rank : 126)	θ value	6.88961 (rank : 122)
Query Neighborhood Hits	150	Target Neighborhood Hits	513	Shared Neighborhood Hits	31
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

UBP25_HUMAN
NC score	0.013334 (rank : 127)	θ value	1.06291 (rank : 73)
Query Neighborhood Hits	150	Target Neighborhood Hits	124	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UHP3, Q9H9W1	Gene names	USP25, USP21
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (USP on chromosome 21).

K0310_HUMAN
NC score	0.012964 (rank : 128)	θ value	8.99809 (rank : 141)
Query Neighborhood Hits	150	Target Neighborhood Hits	420	Shared Neighborhood Hits	23
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

FGD4_MOUSE
NC score	0.012808 (rank : 129)	θ value	6.88961 (rank : 124)
Query Neighborhood Hits	150	Target Neighborhood Hits	227	Shared Neighborhood Hits	21
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

SRA1_HUMAN
NC score	0.012018 (rank : 130)	θ value	6.88961 (rank : 136)
Query Neighborhood Hits	150	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HD15, Q6NVU9, Q8IXM1, Q9HD13, Q9HD14	Gene names	SRA1
Domain Architecture	No domain graphic available
Description	Steroid receptor RNA activator 1 (Steroid receptor RNA activator protein) (SRAP).

BRE1B_HUMAN
NC score	0.011064 (rank : 131)	θ value	3.0926 (rank : 98)
Query Neighborhood Hits	150	Target Neighborhood Hits	1040	Shared Neighborhood Hits	28
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

PARD3_MOUSE
NC score	0.010338 (rank : 132)	θ value	1.06291 (rank : 71)
Query Neighborhood Hits	150	Target Neighborhood Hits	290	Shared Neighborhood Hits	9
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

NPAS2_MOUSE
NC score	0.010216 (rank : 133)	θ value	2.36792 (rank : 93)
Query Neighborhood Hits	150	Target Neighborhood Hits	132	Shared Neighborhood Hits	7
SwissProt Accessions	P97460	Gene names	Npas2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2).

TRHY_HUMAN
NC score	0.010204 (rank : 134)	θ value	3.0926 (rank : 107)
Query Neighborhood Hits	150	Target Neighborhood Hits	1385	Shared Neighborhood Hits	25
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

PESC_HUMAN
NC score	0.009114 (rank : 135)	θ value	6.88961 (rank : 132)
Query Neighborhood Hits	150	Target Neighborhood Hits	90	Shared Neighborhood Hits	2
SwissProt Accessions	O00541, Q6IC29	Gene names	PES1
Domain Architecture
Description	Pescadillo homolog 1.

COFA1_HUMAN
NC score	0.007981 (rank : 136)	θ value	8.99809 (rank : 139)
Query Neighborhood Hits	150	Target Neighborhood Hits	292	Shared Neighborhood Hits	13
SwissProt Accessions	P39059, Q5T6J4, Q9Y4W4	Gene names	COL15A1
Domain Architecture
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV) (Restin) (Related to endostatin)].

PLCG1_MOUSE
NC score	0.007696 (rank : 137)	θ value	6.88961 (rank : 134)
Query Neighborhood Hits	150	Target Neighborhood Hits	314	Shared Neighborhood Hits	12
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

MAGC1_HUMAN
NC score	0.007329 (rank : 138)	θ value	8.99809 (rank : 144)
Query Neighborhood Hits	150	Target Neighborhood Hits	431	Shared Neighborhood Hits	23
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

ARNT2_MOUSE
NC score	0.006928 (rank : 139)	θ value	5.27518 (rank : 116)
Query Neighborhood Hits	150	Target Neighborhood Hits	115	Shared Neighborhood Hits	7
SwissProt Accessions	Q61324	Gene names	Arnt2
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

SYN3_HUMAN
NC score	0.006578 (rank : 140)	θ value	8.99809 (rank : 148)
Query Neighborhood Hits	150	Target Neighborhood Hits	203	Shared Neighborhood Hits	13
SwissProt Accessions	O14994	Gene names	SYN3
Domain Architecture
Description	Synapsin-3 (Synapsin III).

KIF3B_HUMAN
NC score	0.006372 (rank : 141)	θ value	3.0926 (rank : 100)
Query Neighborhood Hits	150	Target Neighborhood Hits	540	Shared Neighborhood Hits	13
SwissProt Accessions	O15066	Gene names	KIF3B, KIAA0359
Domain Architecture
Description	Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B) (HH0048).

KIF3B_MOUSE
NC score	0.006334 (rank : 142)	θ value	3.0926 (rank : 101)
Query Neighborhood Hits	150	Target Neighborhood Hits	533	Shared Neighborhood Hits	12
SwissProt Accessions	Q61771	Gene names	Kif3b
Domain Architecture
Description	Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B).

KIFC3_MOUSE
NC score	0.006233 (rank : 143)	θ value	8.99809 (rank : 142)
Query Neighborhood Hits	150	Target Neighborhood Hits	571	Shared Neighborhood Hits	19
SwissProt Accessions	O35231, Q91YQ2	Gene names	Kifc3
Domain Architecture
Description	Kinesin-like protein KIFC3.

DOK2_HUMAN
NC score	0.006115 (rank : 144)	θ value	8.99809 (rank : 140)
Query Neighborhood Hits	150	Target Neighborhood Hits	46	Shared Neighborhood Hits	4
SwissProt Accessions	O60496	Gene names	DOK2
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)).

K1196_HUMAN
NC score	0.005954 (rank : 145)	θ value	4.03905 (rank : 110)
Query Neighborhood Hits	150	Target Neighborhood Hits	618	Shared Neighborhood Hits	10
SwissProt Accessions	Q96KM6, Q9ULM4	Gene names	KIAA1196
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1196.

AKT1_MOUSE
NC score	0.005908 (rank : 146)	θ value	4.03905 (rank : 109)
Query Neighborhood Hits	150	Target Neighborhood Hits	878	Shared Neighborhood Hits	35
SwissProt Accessions	P31750, Q62274	Gene names	Akt1, Akt, Rac
Domain Architecture
Description	RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-alpha) (AKT1 kinase) (Protein kinase B) (PKB) (C-AKT) (Thymoma viral proto- oncogene).

WNK2_HUMAN
NC score	0.005801 (rank : 147)	θ value	0.21417 (rank : 43)
Query Neighborhood Hits	150	Target Neighborhood Hits	1407	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

AKT1_HUMAN
NC score	0.005758 (rank : 148)	θ value	1.38821 (rank : 75)
Query Neighborhood Hits	150	Target Neighborhood Hits	885	Shared Neighborhood Hits	35
SwissProt Accessions	P31749, Q9BWB6	Gene names	AKT1, PKB, RAC
Domain Architecture
Description	RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-alpha) (Protein kinase B) (PKB) (C-AKT).

CO4A2_MOUSE
NC score	0.005481 (rank : 149)	θ value	0.62314 (rank : 55)
Query Neighborhood Hits	150	Target Neighborhood Hits	492	Shared Neighborhood Hits	10
SwissProt Accessions	P08122, Q61375	Gene names	Col4a2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

ATS7_HUMAN
NC score	0.005191 (rank : 150)	θ value	1.06291 (rank : 68)
Query Neighborhood Hits	150	Target Neighborhood Hits	169	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

WDR23_MOUSE
NC score	0.005069 (rank : 151)	θ value	4.03905 (rank : 114)
Query Neighborhood Hits	150	Target Neighborhood Hits	271	Shared Neighborhood Hits	2
SwissProt Accessions	Q91VU6, Q3U836, Q8JZV8	Gene names	Wdr23, D14Ucla1
Domain Architecture
Description	WD repeat protein 23.

NCA11_MOUSE
NC score	0.003860 (rank : 152)	θ value	4.03905 (rank : 111)
Query Neighborhood Hits	150	Target Neighborhood Hits	661	Shared Neighborhood Hits	20
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

MEGF8_MOUSE
NC score	0.003839 (rank : 153)	θ value	6.88961 (rank : 128)
Query Neighborhood Hits	150	Target Neighborhood Hits	520	Shared Neighborhood Hits	6
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF8_HUMAN
NC score	0.003401 (rank : 154)	θ value	8.99809 (rank : 145)
Query Neighborhood Hits	150	Target Neighborhood Hits	528	Shared Neighborhood Hits	5
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

FINC_MOUSE
NC score	0.001928 (rank : 155)	θ value	6.88961 (rank : 125)
Query Neighborhood Hits	150	Target Neighborhood Hits	309	Shared Neighborhood Hits	5
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

WNK1_HUMAN
NC score	0.001922 (rank : 156)	θ value	4.03905 (rank : 115)
Query Neighborhood Hits	150	Target Neighborhood Hits	1158	Shared Neighborhood Hits	22
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

PAI1_HUMAN
NC score	0.001368 (rank : 157)	θ value	6.88961 (rank : 131)
Query Neighborhood Hits	150	Target Neighborhood Hits	78	Shared Neighborhood Hits	2
SwissProt Accessions	P05121	Gene names	SERPINE1, PAI1, PLANH1
Domain Architecture
Description	Plasminogen activator inhibitor 1 precursor (PAI-1) (Endothelial plasminogen activator inhibitor) (PAI).

LTBP4_MOUSE
NC score	0.001004 (rank : 158)	θ value	5.27518 (rank : 117)
Query Neighborhood Hits	150	Target Neighborhood Hits	607	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

MAST2_HUMAN
NC score	-0.000107 (rank : 159)	θ value	3.0926 (rank : 102)
Query Neighborhood Hits	150	Target Neighborhood Hits	1189	Shared Neighborhood Hits	18
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

SUHW3_MOUSE
NC score	-0.000601 (rank : 160)	θ value	4.03905 (rank : 112)
Query Neighborhood Hits	150	Target Neighborhood Hits	697	Shared Neighborhood Hits	6
SwissProt Accessions	Q6P3Y5, Q6ZPM2, Q8K145	Gene names	Suhw3, Kiaa1584
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 3.

KIT_HUMAN
NC score	-0.000979 (rank : 161)	θ value	8.99809 (rank : 143)
Query Neighborhood Hits	150	Target Neighborhood Hits	953	Shared Neighborhood Hits	10
SwissProt Accessions	P10721, Q9UM99	Gene names	KIT
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

MYLK_MOUSE
NC score	-0.001113 (rank : 162)	θ value	6.88961 (rank : 129)
Query Neighborhood Hits	150	Target Neighborhood Hits	1489	Shared Neighborhood Hits	30
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

ZN219_HUMAN
NC score	-0.003186 (rank : 163)	θ value	8.99809 (rank : 150)
Query Neighborhood Hits	150	Target Neighborhood Hits	876	Shared Neighborhood Hits	11
SwissProt Accessions	Q9P2Y4, Q8IYC1, Q9BW28	Gene names	ZNF219
Domain Architecture	No domain graphic available
Description	Zinc finger protein 219.