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Network neighborhood for query Sequence : GAB1_MOUSE

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GAB1_MOUSE
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GAB1_HUMAN
θ value	0 (rank : 1)	NC score	0.963534 (rank : 2)
Query Neighborhood Hits	233	Target Neighborhood Hits	279	Shared Neighborhood Hits	163
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

GAB1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	233	Target Neighborhood Hits	233	Shared Neighborhood Hits	233
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

GAB2_HUMAN
θ value	1.21547e-113 (rank : 3)	NC score	0.884019 (rank : 3)
Query Neighborhood Hits	233	Target Neighborhood Hits	188	Shared Neighborhood Hits	69
SwissProt Accessions	Q9UQC2, O60317	Gene names	GAB2, KIAA0571
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (pp100).

GAB2_MOUSE
θ value	2.70778e-113 (rank : 4)	NC score	0.872651 (rank : 4)
Query Neighborhood Hits	233	Target Neighborhood Hits	220	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

PKHA1_MOUSE
θ value	3.08544e-08 (rank : 5)	NC score	0.383374 (rank : 5)
Query Neighborhood Hits	233	Target Neighborhood Hits	120	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

MYO10_HUMAN
θ value	3.41135e-07 (rank : 6)	NC score	0.111001 (rank : 47)
Query Neighborhood Hits	233	Target Neighborhood Hits	920	Shared Neighborhood Hits	77
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

PKHA1_HUMAN
θ value	1.29631e-06 (rank : 7)	NC score	0.369785 (rank : 6)
Query Neighborhood Hits	233	Target Neighborhood Hits	127	Shared Neighborhood Hits	52
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA2_MOUSE
θ value	1.09739e-05 (rank : 8)	NC score	0.351647 (rank : 8)
Query Neighborhood Hits	233	Target Neighborhood Hits	116	Shared Neighborhood Hits	45
SwissProt Accessions	Q9ERS5, Q8BY29	Gene names	Plekha2, Tapp2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2) (PH domain-containing adaptor PHAD47).

PHLB2_MOUSE
θ value	1.87187e-05 (rank : 9)	NC score	0.175351 (rank : 21)
Query Neighborhood Hits	233	Target Neighborhood Hits	1016	Shared Neighborhood Hits	55
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

PKHA2_HUMAN
θ value	1.87187e-05 (rank : 10)	NC score	0.355330 (rank : 7)
Query Neighborhood Hits	233	Target Neighborhood Hits	119	Shared Neighborhood Hits	45
SwissProt Accessions	Q9HB19	Gene names	PLEKHA2, TAPP2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2).

PHLB2_HUMAN
θ value	2.44474e-05 (rank : 11)	NC score	0.177518 (rank : 20)
Query Neighborhood Hits	233	Target Neighborhood Hits	964	Shared Neighborhood Hits	50
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

IRS1_HUMAN
θ value	9.29e-05 (rank : 12)	NC score	0.215390 (rank : 17)
Query Neighborhood Hits	233	Target Neighborhood Hits	109	Shared Neighborhood Hits	18
SwissProt Accessions	P35568	Gene names	IRS1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

IRS1_MOUSE
θ value	9.29e-05 (rank : 13)	NC score	0.209796 (rank : 18)
Query Neighborhood Hits	233	Target Neighborhood Hits	112	Shared Neighborhood Hits	19
SwissProt Accessions	P35569	Gene names	Irs1, Irs-1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

PLEK_HUMAN
θ value	0.000121331 (rank : 14)	NC score	0.289000 (rank : 9)
Query Neighborhood Hits	233	Target Neighborhood Hits	110	Shared Neighborhood Hits	43
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

PHLB1_MOUSE
θ value	0.000270298 (rank : 15)	NC score	0.221872 (rank : 16)
Query Neighborhood Hits	233	Target Neighborhood Hits	678	Shared Neighborhood Hits	64
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PLEK_MOUSE
θ value	0.000270298 (rank : 16)	NC score	0.281719 (rank : 10)
Query Neighborhood Hits	233	Target Neighborhood Hits	109	Shared Neighborhood Hits	41
SwissProt Accessions	Q9JHK5, Q9ERI9	Gene names	Plek
Domain Architecture
Description	Pleckstrin.

CNKR2_HUMAN
θ value	0.000786445 (rank : 17)	NC score	0.223118 (rank : 15)
Query Neighborhood Hits	233	Target Neighborhood Hits	197	Shared Neighborhood Hits	37
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_MOUSE
θ value	0.000786445 (rank : 18)	NC score	0.223244 (rank : 14)
Query Neighborhood Hits	233	Target Neighborhood Hits	197	Shared Neighborhood Hits	37
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

PHLB1_HUMAN
θ value	0.000786445 (rank : 19)	NC score	0.201103 (rank : 19)
Query Neighborhood Hits	233	Target Neighborhood Hits	1038	Shared Neighborhood Hits	96
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

DAPP1_MOUSE
θ value	0.00134147 (rank : 20)	NC score	0.231517 (rank : 11)
Query Neighborhood Hits	233	Target Neighborhood Hits	225	Shared Neighborhood Hits	50
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DAPP1_HUMAN
θ value	0.00175202 (rank : 21)	NC score	0.229550 (rank : 12)
Query Neighborhood Hits	233	Target Neighborhood Hits	227	Shared Neighborhood Hits	48
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

RPB1_HUMAN
θ value	0.00175202 (rank : 22)	NC score	0.136578 (rank : 28)
Query Neighborhood Hits	233	Target Neighborhood Hits	362	Shared Neighborhood Hits	27
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_MOUSE
θ value	0.00175202 (rank : 23)	NC score	0.136795 (rank : 27)
Query Neighborhood Hits	233	Target Neighborhood Hits	363	Shared Neighborhood Hits	27
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

TARSH_HUMAN
θ value	0.00175202 (rank : 24)	NC score	0.139623 (rank : 26)
Query Neighborhood Hits	233	Target Neighborhood Hits	768	Shared Neighborhood Hits	102
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

CASL_HUMAN
θ value	0.00228821 (rank : 25)	NC score	0.096138 (rank : 60)
Query Neighborhood Hits	233	Target Neighborhood Hits	259	Shared Neighborhood Hits	22
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

CNKR1_HUMAN
θ value	0.00298849 (rank : 26)	NC score	0.225241 (rank : 13)
Query Neighborhood Hits	233	Target Neighborhood Hits	154	Shared Neighborhood Hits	40
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

RAPH1_HUMAN
θ value	0.00869519 (rank : 27)	NC score	0.131895 (rank : 32)
Query Neighborhood Hits	233	Target Neighborhood Hits	593	Shared Neighborhood Hits	67
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

CASL_MOUSE
θ value	0.0148317 (rank : 28)	NC score	0.093912 (rank : 61)
Query Neighborhood Hits	233	Target Neighborhood Hits	225	Shared Neighborhood Hits	15
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

DOC10_HUMAN
θ value	0.0148317 (rank : 29)	NC score	0.121136 (rank : 39)
Query Neighborhood Hits	233	Target Neighborhood Hits	88	Shared Neighborhood Hits	21
SwissProt Accessions	Q96BY6, O75178, Q9NW06, Q9NXI8	Gene names	DOCK10, KIAA0694
Domain Architecture
Description	Dedicator of cytokinesis protein 10 (Protein zizimin 3).

SRRM2_HUMAN
θ value	0.0193708 (rank : 30)	NC score	0.131941 (rank : 31)
Query Neighborhood Hits	233	Target Neighborhood Hits	1296	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

BMX_HUMAN
θ value	0.0252991 (rank : 31)	NC score	0.027792 (rank : 226)
Query Neighborhood Hits	233	Target Neighborhood Hits	942	Shared Neighborhood Hits	35
SwissProt Accessions	P51813, O60564, Q12871	Gene names	BMX
Domain Architecture
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38).

PRG4_MOUSE
θ value	0.0252991 (rank : 32)	NC score	0.070900 (rank : 96)
Query Neighborhood Hits	233	Target Neighborhood Hits	624	Shared Neighborhood Hits	41
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

IWS1_HUMAN
θ value	0.0330416 (rank : 33)	NC score	0.063409 (rank : 119)
Query Neighborhood Hits	233	Target Neighborhood Hits	1241	Shared Neighborhood Hits	62
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

SRRM1_HUMAN
θ value	0.0330416 (rank : 34)	NC score	0.118644 (rank : 41)
Query Neighborhood Hits	233	Target Neighborhood Hits	690	Shared Neighborhood Hits	49
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

BMX_MOUSE
θ value	0.0431538 (rank : 35)	NC score	0.026537 (rank : 230)
Query Neighborhood Hits	233	Target Neighborhood Hits	912	Shared Neighborhood Hits	34
SwissProt Accessions	P97504	Gene names	Bmx
Domain Architecture	No domain graphic available
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein homolog).

SWP70_MOUSE
θ value	0.0431538 (rank : 36)	NC score	0.118348 (rank : 42)
Query Neighborhood Hits	233	Target Neighborhood Hits	1097	Shared Neighborhood Hits	63
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

BAI1_HUMAN
θ value	0.0563607 (rank : 37)	NC score	0.032668 (rank : 214)
Query Neighborhood Hits	233	Target Neighborhood Hits	375	Shared Neighborhood Hits	20
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

DOCK9_MOUSE
θ value	0.0563607 (rank : 38)	NC score	0.109079 (rank : 50)
Query Neighborhood Hits	233	Target Neighborhood Hits	79	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BIK4, Q921Y6	Gene names	Dock9, D14Wsu89e, Kiaa1058
Domain Architecture
Description	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin 1).

MRIP_HUMAN
θ value	0.0563607 (rank : 39)	NC score	0.136177 (rank : 29)
Query Neighborhood Hits	233	Target Neighborhood Hits	578	Shared Neighborhood Hits	45
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

SRRM1_MOUSE
θ value	0.0563607 (rank : 40)	NC score	0.122403 (rank : 37)
Query Neighborhood Hits	233	Target Neighborhood Hits	966	Shared Neighborhood Hits	79
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

TMEPA_MOUSE
θ value	0.0563607 (rank : 41)	NC score	0.088013 (rank : 67)
Query Neighborhood Hits	233	Target Neighborhood Hits	46	Shared Neighborhood Hits	18
SwissProt Accessions	Q9D7R2, Q9EQH9	Gene names	Tmepai, N4wbp4
Domain Architecture	No domain graphic available
Description	Transmembrane prostate androgen-induced protein (NEDD4 WW domain- binding protein 4).

MLL2_HUMAN
θ value	0.0736092 (rank : 42)	NC score	0.065334 (rank : 115)
Query Neighborhood Hits	233	Target Neighborhood Hits	1788	Shared Neighborhood Hits	99
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

SN1L2_MOUSE
θ value	0.0736092 (rank : 43)	NC score	0.010778 (rank : 257)
Query Neighborhood Hits	233	Target Neighborhood Hits	944	Shared Neighborhood Hits	20
SwissProt Accessions	Q8CFH6	Gene names	Snf1lk2, Sik2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SNF1-like kinase 2 (EC 2.7.11.1) (Salt-inducible kinase 2).

TARA_HUMAN
θ value	0.0736092 (rank : 44)	NC score	0.127942 (rank : 34)
Query Neighborhood Hits	233	Target Neighborhood Hits	1626	Shared Neighborhood Hits	122
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

EGR2_MOUSE
θ value	0.0961366 (rank : 45)	NC score	0.008777 (rank : 266)
Query Neighborhood Hits	233	Target Neighborhood Hits	745	Shared Neighborhood Hits	14
SwissProt Accessions	P08152	Gene names	Egr2, Egr-2, Krox-20, Zfp-25
Domain Architecture	No domain graphic available
Description	Early growth response protein 2 (EGR-2) (Krox-20 protein).

MUC1_HUMAN
θ value	0.0961366 (rank : 46)	NC score	0.091367 (rank : 62)
Query Neighborhood Hits	233	Target Neighborhood Hits	975	Shared Neighborhood Hits	103
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

BTBDC_HUMAN
θ value	0.125558 (rank : 47)	NC score	0.105297 (rank : 54)
Query Neighborhood Hits	233	Target Neighborhood Hits	248	Shared Neighborhood Hits	26
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

CEND2_HUMAN
θ value	0.125558 (rank : 48)	NC score	0.105469 (rank : 53)
Query Neighborhood Hits	233	Target Neighborhood Hits	166	Shared Neighborhood Hits	37
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

RHG25_HUMAN
θ value	0.125558 (rank : 49)	NC score	0.125973 (rank : 35)
Query Neighborhood Hits	233	Target Neighborhood Hits	550	Shared Neighborhood Hits	57
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

SWP70_HUMAN
θ value	0.125558 (rank : 50)	NC score	0.115797 (rank : 43)
Query Neighborhood Hits	233	Target Neighborhood Hits	973	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

AB1IP_HUMAN
θ value	0.163984 (rank : 51)	NC score	0.082727 (rank : 71)
Query Neighborhood Hits	233	Target Neighborhood Hits	213	Shared Neighborhood Hits	35
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

ACK1_HUMAN
θ value	0.163984 (rank : 52)	NC score	0.023109 (rank : 238)
Query Neighborhood Hits	233	Target Neighborhood Hits	1140	Shared Neighborhood Hits	69
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

WASF4_HUMAN
θ value	0.163984 (rank : 53)	NC score	0.079040 (rank : 79)
Query Neighborhood Hits	233	Target Neighborhood Hits	282	Shared Neighborhood Hits	35
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

AB1IP_MOUSE
θ value	0.21417 (rank : 54)	NC score	0.089254 (rank : 63)
Query Neighborhood Hits	233	Target Neighborhood Hits	181	Shared Neighborhood Hits	31
SwissProt Accessions	Q8R5A3, O35329, Q8BRU0, Q99KV8	Gene names	Apbb1ip, Prel1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 48).

ACK1_MOUSE
θ value	0.21417 (rank : 55)	NC score	0.021651 (rank : 243)
Query Neighborhood Hits	233	Target Neighborhood Hits	1080	Shared Neighborhood Hits	57
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

DOCK9_HUMAN
θ value	0.21417 (rank : 56)	NC score	0.099614 (rank : 59)
Query Neighborhood Hits	233	Target Neighborhood Hits	82	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BZ29, Q5JUD4, Q5JUD6, Q5T2Q1, Q5TAN8, Q9BZ25, Q9BZ26, Q9BZ27, Q9BZ28, Q9UPU4	Gene names	DOCK9, KIAA1058
Domain Architecture
Description	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin 1).

LRP6_HUMAN
θ value	0.21417 (rank : 57)	NC score	0.029449 (rank : 220)
Query Neighborhood Hits	233	Target Neighborhood Hits	235	Shared Neighborhood Hits	8
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP6_MOUSE
θ value	0.21417 (rank : 58)	NC score	0.029914 (rank : 217)
Query Neighborhood Hits	233	Target Neighborhood Hits	232	Shared Neighborhood Hits	9
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

PKHA5_HUMAN
θ value	0.21417 (rank : 59)	NC score	0.151860 (rank : 24)
Query Neighborhood Hits	233	Target Neighborhood Hits	455	Shared Neighborhood Hits	57
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

RBM16_HUMAN
θ value	0.21417 (rank : 60)	NC score	0.067179 (rank : 107)
Query Neighborhood Hits	233	Target Neighborhood Hits	300	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UPN6, Q5TBU6, Q9BQN8, Q9BX43	Gene names	RBM16, KIAA1116
Domain Architecture
Description	Putative RNA-binding protein 16 (RNA-binding motif protein 16).

S23IP_HUMAN
θ value	0.21417 (rank : 61)	NC score	0.048589 (rank : 166)
Query Neighborhood Hits	233	Target Neighborhood Hits	134	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y6Y8, Q8IXH5, Q9BUK5	Gene names	SEC23IP
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein (p125).

TARA_MOUSE
θ value	0.21417 (rank : 62)	NC score	0.133521 (rank : 30)
Query Neighborhood Hits	233	Target Neighborhood Hits	1133	Shared Neighborhood Hits	97
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

ZCHC8_MOUSE
θ value	0.21417 (rank : 63)	NC score	0.053784 (rank : 146)
Query Neighborhood Hits	233	Target Neighborhood Hits	134	Shared Neighborhood Hits	13
SwissProt Accessions	Q9CYA6, Q3TK71, Q8CCB7, Q91WQ1	Gene names	Zcchc8
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 8.

RNC_HUMAN
θ value	0.279714 (rank : 64)	NC score	0.071616 (rank : 93)
Query Neighborhood Hits	233	Target Neighborhood Hits	176	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NRR4, Q7Z5V2, Q86YH0, Q9NW73, Q9Y2V9, Q9Y4Y0	Gene names	RNASEN, RN3, RNASE3L
Domain Architecture
Description	Ribonuclease III (EC 3.1.26.3) (RNase III) (Drosha) (p241).

WASF1_HUMAN
θ value	0.279714 (rank : 65)	NC score	0.081284 (rank : 74)
Query Neighborhood Hits	233	Target Neighborhood Hits	260	Shared Neighborhood Hits	31
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

ZDHC8_HUMAN
θ value	0.279714 (rank : 66)	NC score	0.041382 (rank : 186)
Query Neighborhood Hits	233	Target Neighborhood Hits	234	Shared Neighborhood Hits	27
SwissProt Accessions	Q9ULC8, Q6ICL1, Q6ZNF5, Q7Z6L9	Gene names	ZDHHC8, KIAA1292, ZDHHCL1, ZNF378
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8) (Zinc finger protein 378).

ARHG7_MOUSE
θ value	0.365318 (rank : 67)	NC score	0.028835 (rank : 222)
Query Neighborhood Hits	233	Target Neighborhood Hits	396	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

CEND1_HUMAN
θ value	0.365318 (rank : 68)	NC score	0.110588 (rank : 49)
Query Neighborhood Hits	233	Target Neighborhood Hits	284	Shared Neighborhood Hits	48
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

DIAP1_HUMAN
θ value	0.365318 (rank : 69)	NC score	0.051992 (rank : 153)
Query Neighborhood Hits	233	Target Neighborhood Hits	784	Shared Neighborhood Hits	36
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

DREB_MOUSE
θ value	0.365318 (rank : 70)	NC score	0.048909 (rank : 164)
Query Neighborhood Hits	233	Target Neighborhood Hits	446	Shared Neighborhood Hits	26
SwissProt Accessions	Q9QXS6, Q922X1, Q9QXS5	Gene names	Dbn1, Drba
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

HNRL1_HUMAN
θ value	0.365318 (rank : 71)	NC score	0.054449 (rank : 144)
Query Neighborhood Hits	233	Target Neighborhood Hits	173	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BUJ2, O76022, Q6ZSZ0, Q7L8P4, Q8N6Z4, Q96G37, Q9HAL3, Q9UG75	Gene names	HNRPUL1, E1BAP5
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1 (Adenovirus early region 1B-associated protein 5) (E1B-55 kDa-associated protein 5) (E1B-AP5).

LTBP4_MOUSE
θ value	0.365318 (rank : 72)	NC score	0.014623 (rank : 251)
Query Neighborhood Hits	233	Target Neighborhood Hits	607	Shared Neighborhood Hits	26
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

TMEPA_HUMAN
θ value	0.365318 (rank : 73)	NC score	0.076973 (rank : 83)
Query Neighborhood Hits	233	Target Neighborhood Hits	46	Shared Neighborhood Hits	11
SwissProt Accessions	Q969W9, Q5TDR6, Q96B72, Q9UJD3	Gene names	TMEPAI, PMEPA1, STAG1
Domain Architecture
Description	Transmembrane prostate androgen-induced protein (Solid tumor- associated 1 protein).

WASL_MOUSE
θ value	0.365318 (rank : 74)	NC score	0.082451 (rank : 72)
Query Neighborhood Hits	233	Target Neighborhood Hits	339	Shared Neighborhood Hits	36
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

ZIM10_MOUSE
θ value	0.365318 (rank : 75)	NC score	0.058984 (rank : 131)
Query Neighborhood Hits	233	Target Neighborhood Hits	430	Shared Neighborhood Hits	54
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ANR41_HUMAN
θ value	0.47712 (rank : 76)	NC score	0.026544 (rank : 229)
Query Neighborhood Hits	233	Target Neighborhood Hits	332	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

BAI1_MOUSE
θ value	0.47712 (rank : 77)	NC score	0.029728 (rank : 219)
Query Neighborhood Hits	233	Target Neighborhood Hits	340	Shared Neighborhood Hits	16
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

CENB2_HUMAN
θ value	0.47712 (rank : 78)	NC score	0.080683 (rank : 75)
Query Neighborhood Hits	233	Target Neighborhood Hits	425	Shared Neighborhood Hits	46
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

DYN3_HUMAN
θ value	0.47712 (rank : 79)	NC score	0.039951 (rank : 189)
Query Neighborhood Hits	233	Target Neighborhood Hits	158	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UQ16, O14982, O95555, Q5W129, Q9H0P3, Q9H548, Q9NQ68, Q9NQN6	Gene names	DNM3, KIAA0820
Domain Architecture
Description	Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin).

HNRL1_MOUSE
θ value	0.47712 (rank : 80)	NC score	0.059384 (rank : 128)
Query Neighborhood Hits	233	Target Neighborhood Hits	200	Shared Neighborhood Hits	28
SwissProt Accessions	Q8VDM6, Q3U201, Q3UPB0, Q6AZA7, Q8BY45, Q8K365	Gene names	Hnrpul1
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1.

PKP4_HUMAN
θ value	0.47712 (rank : 81)	NC score	0.032841 (rank : 213)
Query Neighborhood Hits	233	Target Neighborhood Hits	107	Shared Neighborhood Hits	8
SwissProt Accessions	Q99569	Gene names	PKP4
Domain Architecture
Description	Plakophilin-4 (p0071).

RASA1_HUMAN
θ value	0.47712 (rank : 82)	NC score	0.111818 (rank : 45)
Query Neighborhood Hits	233	Target Neighborhood Hits	258	Shared Neighborhood Hits	38
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

SPEG_MOUSE
θ value	0.47712 (rank : 83)	NC score	0.021709 (rank : 242)
Query Neighborhood Hits	233	Target Neighborhood Hits	1959	Shared Neighborhood Hits	92
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

UBP2L_HUMAN
θ value	0.47712 (rank : 84)	NC score	0.073859 (rank : 88)
Query Neighborhood Hits	233	Target Neighborhood Hits	170	Shared Neighborhood Hits	20
SwissProt Accessions	Q14157, Q5VU75, Q5VU76, Q9BTU3, Q9UGL5	Gene names	UBAP2L, KIAA0144, NICE4
Domain Architecture
Description	Ubiquitin-associated protein 2-like (Protein NICE-4).

CENB1_HUMAN
θ value	0.62314 (rank : 85)	NC score	0.075325 (rank : 85)
Query Neighborhood Hits	233	Target Neighborhood Hits	383	Shared Neighborhood Hits	44
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

CR001_HUMAN
θ value	0.62314 (rank : 86)	NC score	0.070299 (rank : 98)
Query Neighborhood Hits	233	Target Neighborhood Hits	68	Shared Neighborhood Hits	10
SwissProt Accessions	O15165, O15166, O15167, O15168, Q6NXP3	Gene names	C18orf1
Domain Architecture
Description	Protein C18orf1.

CR001_MOUSE
θ value	0.62314 (rank : 87)	NC score	0.069827 (rank : 100)
Query Neighborhood Hits	233	Target Neighborhood Hits	67	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BWJ4	Gene names	D18Ertd653e
Domain Architecture	No domain graphic available
Description	Protein C18orf1 homolog.

PDCD7_MOUSE
θ value	0.62314 (rank : 88)	NC score	0.065884 (rank : 113)
Query Neighborhood Hits	233	Target Neighborhood Hits	214	Shared Neighborhood Hits	14
SwissProt Accessions	Q9WTY1, Q8R5D9	Gene names	Pdcd7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18).

RASA2_MOUSE
θ value	0.62314 (rank : 89)	NC score	0.104109 (rank : 55)
Query Neighborhood Hits	233	Target Neighborhood Hits	159	Shared Neighborhood Hits	35
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

RHG25_MOUSE
θ value	0.62314 (rank : 90)	NC score	0.106742 (rank : 51)
Query Neighborhood Hits	233	Target Neighborhood Hits	492	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

STX5_HUMAN
θ value	0.62314 (rank : 91)	NC score	0.036830 (rank : 199)
Query Neighborhood Hits	233	Target Neighborhood Hits	74	Shared Neighborhood Hits	4
SwissProt Accessions	Q13190, Q5U0D4, Q7Z3T6, Q9BUG1	Gene names	STX5, STX5A
Domain Architecture
Description	Syntaxin-5.

TAF3_MOUSE
θ value	0.62314 (rank : 92)	NC score	0.057004 (rank : 134)
Query Neighborhood Hits	233	Target Neighborhood Hits	463	Shared Neighborhood Hits	32
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

WASIP_MOUSE
θ value	0.62314 (rank : 93)	NC score	0.111300 (rank : 46)
Query Neighborhood Hits	233	Target Neighborhood Hits	392	Shared Neighborhood Hits	47
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

WASL_HUMAN
θ value	0.62314 (rank : 94)	NC score	0.077849 (rank : 81)
Query Neighborhood Hits	233	Target Neighborhood Hits	312	Shared Neighborhood Hits	34
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

CENB5_HUMAN
θ value	0.813845 (rank : 95)	NC score	0.072766 (rank : 91)
Query Neighborhood Hits	233	Target Neighborhood Hits	395	Shared Neighborhood Hits	46
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

FBLI1_MOUSE
θ value	0.813845 (rank : 96)	NC score	0.022586 (rank : 239)
Query Neighborhood Hits	233	Target Neighborhood Hits	228	Shared Neighborhood Hits	13
SwissProt Accessions	Q71FD7, Q99J35	Gene names	Fblim1, Cal
Domain Architecture	No domain graphic available
Description	Filamin-binding LIM protein 1 (CSX-associated LIM).

ZDHC8_MOUSE
θ value	0.813845 (rank : 97)	NC score	0.038160 (rank : 195)
Query Neighborhood Hits	233	Target Neighborhood Hits	243	Shared Neighborhood Hits	19
SwissProt Accessions	Q5Y5T5, Q7TNF7	Gene names	Zdhhc8
Domain Architecture	No domain graphic available
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8).

3BP1_HUMAN
θ value	1.06291 (rank : 98)	NC score	0.050536 (rank : 159)
Query Neighborhood Hits	233	Target Neighborhood Hits	376	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

FHOD1_MOUSE
θ value	1.06291 (rank : 99)	NC score	0.052375 (rank : 151)
Query Neighborhood Hits	233	Target Neighborhood Hits	217	Shared Neighborhood Hits	27
SwissProt Accessions	Q6P9Q4, Q8BMK2	Gene names	Fhod1, Fhos1
Domain Architecture	No domain graphic available
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

KLF10_MOUSE
θ value	1.06291 (rank : 100)	NC score	0.007055 (rank : 270)
Query Neighborhood Hits	233	Target Neighborhood Hits	741	Shared Neighborhood Hits	12
SwissProt Accessions	O89091	Gene names	Klf10, Gdnfif, Tieg, Tieg1
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 10 (Transforming growth factor-beta-inducible early growth response protein 1) (TGFB-inducible early growth response protein 1) (TIEG-1) (GDNF-inducible factor) (Transcription factor GIF) (mGIF).

KLF2_MOUSE
θ value	1.06291 (rank : 101)	NC score	0.005822 (rank : 274)
Query Neighborhood Hits	233	Target Neighborhood Hits	738	Shared Neighborhood Hits	8
SwissProt Accessions	Q60843	Gene names	Klf2, Lklf
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 2 (Lung krueppel-like factor).

MRIP_MOUSE
θ value	1.06291 (rank : 102)	NC score	0.125515 (rank : 36)
Query Neighborhood Hits	233	Target Neighborhood Hits	569	Shared Neighborhood Hits	47
SwissProt Accessions	P97434, Q3TBR5, Q3TC85, Q3TRS0, Q3U1Y8, Q3U3E4, Q5SWZ3, Q5SWZ4, Q5SWZ7, Q6P559, Q80YC8	Gene names	Mrip, Kiaa0864, Rhoip3
Domain Architecture
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (p116Rip) (RIP3).

NECD_HUMAN
θ value	1.06291 (rank : 103)	NC score	0.023967 (rank : 237)
Query Neighborhood Hits	233	Target Neighborhood Hits	82	Shared Neighborhood Hits	11
SwissProt Accessions	Q99608	Gene names	NDN
Domain Architecture
Description	Necdin.

R3HD2_MOUSE
θ value	1.06291 (rank : 104)	NC score	0.042856 (rank : 181)
Query Neighborhood Hits	233	Target Neighborhood Hits	397	Shared Neighborhood Hits	37
SwissProt Accessions	Q80TM6, Q80YB1, Q8BLS5, Q9CW50	Gene names	R3hdm2, Kiaa1002
Domain Architecture
Description	R3H domain-containing protein 2.

T22D2_HUMAN
θ value	1.06291 (rank : 105)	NC score	0.044803 (rank : 176)
Query Neighborhood Hits	233	Target Neighborhood Hits	250	Shared Neighborhood Hits	20
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

AF9_HUMAN
θ value	1.38821 (rank : 106)	NC score	0.054951 (rank : 142)
Query Neighborhood Hits	233	Target Neighborhood Hits	202	Shared Neighborhood Hits	14
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

BLNK_MOUSE
θ value	1.38821 (rank : 107)	NC score	0.088672 (rank : 65)
Query Neighborhood Hits	233	Target Neighborhood Hits	296	Shared Neighborhood Hits	49
SwissProt Accessions	Q9QUN3, O88504	Gene names	Blnk, Bash, Ly57, Slp65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65) (Lymphocyte antigen 57).

BRD4_MOUSE
θ value	1.38821 (rank : 108)	NC score	0.046953 (rank : 172)
Query Neighborhood Hits	233	Target Neighborhood Hits	845	Shared Neighborhood Hits	56
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

BTG3_HUMAN
θ value	1.38821 (rank : 109)	NC score	0.050668 (rank : 157)
Query Neighborhood Hits	233	Target Neighborhood Hits	32	Shared Neighborhood Hits	9
SwissProt Accessions	Q14201, Q96ET7	Gene names	BTG3, ANA, TOB5
Domain Architecture
Description	BTG3 protein (Tob5 protein) (Abundant in neuroepithelium area protein).

DIAP2_MOUSE
θ value	1.38821 (rank : 110)	NC score	0.038100 (rank : 196)
Query Neighborhood Hits	233	Target Neighborhood Hits	260	Shared Neighborhood Hits	18
SwissProt Accessions	O70566, Q8C2G8	Gene names	Diaph2, Diap2
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2) (mDia3).

DIAP3_HUMAN
θ value	1.38821 (rank : 111)	NC score	0.033849 (rank : 208)
Query Neighborhood Hits	233	Target Neighborhood Hits	209	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NSV4, Q5T2S7, Q5XKF6, Q6MZF0, Q6NUP0, Q86VS4, Q8NAV4	Gene names	DIAPH3, DIAP3
Domain Architecture	No domain graphic available
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3).

FGD1_HUMAN
θ value	1.38821 (rank : 112)	NC score	0.022195 (rank : 241)
Query Neighborhood Hits	233	Target Neighborhood Hits	367	Shared Neighborhood Hits	41
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

GSCR1_HUMAN
θ value	1.38821 (rank : 113)	NC score	0.067736 (rank : 105)
Query Neighborhood Hits	233	Target Neighborhood Hits	674	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

KCT2_MOUSE
θ value	1.38821 (rank : 114)	NC score	0.036488 (rank : 201)
Query Neighborhood Hits	233	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K201, Q5SVC5, Q922L7, Q9CVN1	Gene names	Kct2
Domain Architecture	No domain graphic available
Description	Keratinocytes-associated transmembrane protein 2 precursor.

NACAM_MOUSE
θ value	1.38821 (rank : 115)	NC score	0.100554 (rank : 57)
Query Neighborhood Hits	233	Target Neighborhood Hits	1866	Shared Neighborhood Hits	125
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

OSBL3_MOUSE
θ value	1.38821 (rank : 116)	NC score	0.049166 (rank : 163)
Query Neighborhood Hits	233	Target Neighborhood Hits	86	Shared Neighborhood Hits	25
SwissProt Accessions	Q9DBS9	Gene names	Osbpl3, Orp3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

PKP4_MOUSE
θ value	1.38821 (rank : 117)	NC score	0.024656 (rank : 235)
Query Neighborhood Hits	233	Target Neighborhood Hits	129	Shared Neighborhood Hits	7
SwissProt Accessions	Q68FH0, Q640N0, Q68G56, Q8BK47, Q8BVH1, Q9CRE3	Gene names	Pkp4, Armrp
Domain Architecture	No domain graphic available
Description	Plakophilin-4 (Armadillo-related protein).

PTN23_HUMAN
θ value	1.38821 (rank : 118)	NC score	0.028280 (rank : 223)
Query Neighborhood Hits	233	Target Neighborhood Hits	646	Shared Neighborhood Hits	37
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

PYGO2_HUMAN
θ value	1.38821 (rank : 119)	NC score	0.045068 (rank : 175)
Query Neighborhood Hits	233	Target Neighborhood Hits	189	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BRQ0, Q8WYZ4, Q96CY2	Gene names	PYGO2
Domain Architecture
Description	Pygopus homolog 2.

SOS1_HUMAN
θ value	1.38821 (rank : 120)	NC score	0.028951 (rank : 221)
Query Neighborhood Hits	233	Target Neighborhood Hits	274	Shared Neighborhood Hits	25
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

UBP2L_MOUSE
θ value	1.38821 (rank : 121)	NC score	0.052691 (rank : 150)
Query Neighborhood Hits	233	Target Neighborhood Hits	173	Shared Neighborhood Hits	18
SwissProt Accessions	Q80X50, Q8BIT6, Q8BIW4, Q8BJ01, Q8CIG7, Q8K102, Q9CRT6	Gene names	Ubap2l
Domain Architecture	No domain graphic available
Description	Ubiquitin-associated protein 2-like.

WASIP_HUMAN
θ value	1.38821 (rank : 122)	NC score	0.088787 (rank : 64)
Query Neighborhood Hits	233	Target Neighborhood Hits	458	Shared Neighborhood Hits	49
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

ZIM10_HUMAN
θ value	1.38821 (rank : 123)	NC score	0.067287 (rank : 106)
Query Neighborhood Hits	233	Target Neighborhood Hits	577	Shared Neighborhood Hits	78
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

CDSN_MOUSE
θ value	1.81305 (rank : 124)	NC score	0.030300 (rank : 216)
Query Neighborhood Hits	233	Target Neighborhood Hits	131	Shared Neighborhood Hits	7
SwissProt Accessions	Q7TPC1	Gene names	Cdsn
Domain Architecture	No domain graphic available
Description	Corneodesmosin precursor.

CSKI1_MOUSE
θ value	1.81305 (rank : 125)	NC score	0.026116 (rank : 232)
Query Neighborhood Hits	233	Target Neighborhood Hits	1031	Shared Neighborhood Hits	92
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CT151_HUMAN
θ value	1.81305 (rank : 126)	NC score	0.045749 (rank : 173)
Query Neighborhood Hits	233	Target Neighborhood Hits	382	Shared Neighborhood Hits	31
SwissProt Accessions	Q8NC74, Q8N4Z9, Q9BR75, Q9H0Y9	Gene names	C20orf151
Domain Architecture
Description	Uncharacterized protein C20orf151.

LCP2_HUMAN
θ value	1.81305 (rank : 127)	NC score	0.102491 (rank : 56)
Query Neighborhood Hits	233	Target Neighborhood Hits	531	Shared Neighborhood Hits	85
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

LR37A_HUMAN
θ value	1.81305 (rank : 128)	NC score	0.053432 (rank : 147)
Query Neighborhood Hits	233	Target Neighborhood Hits	720	Shared Neighborhood Hits	60
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

OSBL3_HUMAN
θ value	1.81305 (rank : 129)	NC score	0.048246 (rank : 168)
Query Neighborhood Hits	233	Target Neighborhood Hits	93	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H4L5, O14591, O43357, O43358, Q8N702, Q8N703, Q8N704, Q8NFH0, Q8NFH1, Q8NI12, Q8NI13, Q9BZF4, Q9UED6	Gene names	OSBPL3, KIAA0704, ORP3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

PCD15_HUMAN
θ value	1.81305 (rank : 130)	NC score	0.009586 (rank : 259)
Query Neighborhood Hits	233	Target Neighborhood Hits	289	Shared Neighborhood Hits	13
SwissProt Accessions	Q96QU1, Q96QT8	Gene names	PCDH15
Domain Architecture
Description	Protocadherin-15 precursor.

PCLO_MOUSE
θ value	1.81305 (rank : 131)	NC score	0.061863 (rank : 121)
Query Neighborhood Hits	233	Target Neighborhood Hits	2275	Shared Neighborhood Hits	129
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

TCRG1_MOUSE
θ value	1.81305 (rank : 132)	NC score	0.036310 (rank : 202)
Query Neighborhood Hits	233	Target Neighborhood Hits	947	Shared Neighborhood Hits	45
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

BAG3_MOUSE
θ value	2.36792 (rank : 133)	NC score	0.074159 (rank : 87)
Query Neighborhood Hits	233	Target Neighborhood Hits	513	Shared Neighborhood Hits	81
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

BTG3_MOUSE
θ value	2.36792 (rank : 134)	NC score	0.043896 (rank : 179)
Query Neighborhood Hits	233	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	P50615, Q62328	Gene names	Btg3, Ana, Tob5
Domain Architecture
Description	BTG3 protein (Tob5 protein) (Abundant in neuroepithelium area protein).

CABYR_MOUSE
θ value	2.36792 (rank : 135)	NC score	0.037819 (rank : 197)
Query Neighborhood Hits	233	Target Neighborhood Hits	80	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D424, Q91Y41, Q91Y42	Gene names	Cabyr, Cbp86
Domain Architecture	No domain graphic available
Description	Calcium-binding tyrosine phosphorylation-regulated protein (Calcium- binding protein 86) (Testis-specific calcium-binding protein CBP86).

CCNK_MOUSE
θ value	2.36792 (rank : 136)	NC score	0.048097 (rank : 169)
Query Neighborhood Hits	233	Target Neighborhood Hits	350	Shared Neighborhood Hits	35
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

CD2AP_HUMAN
θ value	2.36792 (rank : 137)	NC score	0.027883 (rank : 224)
Query Neighborhood Hits	233	Target Neighborhood Hits	315	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

DDX20_MOUSE
θ value	2.36792 (rank : 138)	NC score	0.008087 (rank : 267)
Query Neighborhood Hits	233	Target Neighborhood Hits	177	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

DPOD3_HUMAN
θ value	2.36792 (rank : 139)	NC score	0.042161 (rank : 185)
Query Neighborhood Hits	233	Target Neighborhood Hits	109	Shared Neighborhood Hits	11
SwissProt Accessions	Q15054	Gene names	POLD3, KIAA0039
Domain Architecture	No domain graphic available
Description	DNA polymerase subunit delta 3 (DNA polymerase subunit delta p66).

FMN1A_MOUSE
θ value	2.36792 (rank : 140)	NC score	0.044412 (rank : 178)
Query Neighborhood Hits	233	Target Neighborhood Hits	423	Shared Neighborhood Hits	37
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

FMN1B_MOUSE
θ value	2.36792 (rank : 141)	NC score	0.042281 (rank : 183)
Query Neighborhood Hits	233	Target Neighborhood Hits	447	Shared Neighborhood Hits	33
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

FOXC1_MOUSE
θ value	2.36792 (rank : 142)	NC score	0.007251 (rank : 268)
Query Neighborhood Hits	233	Target Neighborhood Hits	218	Shared Neighborhood Hits	10
SwissProt Accessions	Q61572, O88409, Q61582	Gene names	Foxc1, Fkh1, Fkhl7, Freac3, Mf1
Domain Architecture
Description	Forkhead box protein C1 (Forkhead-related protein FKHL7) (Forkhead- related transcription factor 3) (FREAC-3) (Transcription factor FKH-1) (Mesoderm/mesenchyme forkhead 1) (MF-1).

GNAS3_HUMAN
θ value	2.36792 (rank : 143)	NC score	0.055845 (rank : 137)
Query Neighborhood Hits	233	Target Neighborhood Hits	71	Shared Neighborhood Hits	7
SwissProt Accessions	O95467, O95417	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Neuroendocrine secretory protein 55 (NESP55) [Contains: LHAL tetrapeptide; GPIPIRRH peptide].

MAGC1_HUMAN
θ value	2.36792 (rank : 144)	NC score	0.047195 (rank : 170)
Query Neighborhood Hits	233	Target Neighborhood Hits	431	Shared Neighborhood Hits	40
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

MTMR5_HUMAN
θ value	2.36792 (rank : 145)	NC score	0.086494 (rank : 68)
Query Neighborhood Hits	233	Target Neighborhood Hits	141	Shared Neighborhood Hits	30
SwissProt Accessions	O95248, O60228, Q5JXD8, Q5PPM2, Q96GR9, Q9UGB8	Gene names	SBF1, MTMR5
Domain Architecture
Description	SET-binding factor 1 (Sbf1) (Myotubularin-related protein 5).

NCOA6_HUMAN
θ value	2.36792 (rank : 146)	NC score	0.088227 (rank : 66)
Query Neighborhood Hits	233	Target Neighborhood Hits	1202	Shared Neighborhood Hits	118
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NCOA6_MOUSE
θ value	2.36792 (rank : 147)	NC score	0.067105 (rank : 108)
Query Neighborhood Hits	233	Target Neighborhood Hits	1076	Shared Neighborhood Hits	102
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

NCOR2_HUMAN
θ value	2.36792 (rank : 148)	NC score	0.040973 (rank : 187)
Query Neighborhood Hits	233	Target Neighborhood Hits	870	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

P3C2B_HUMAN
θ value	2.36792 (rank : 149)	NC score	0.011424 (rank : 255)
Query Neighborhood Hits	233	Target Neighborhood Hits	148	Shared Neighborhood Hits	7
SwissProt Accessions	O00750, O95666, Q5SW99	Gene names	PIK3C2B
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-beta) (PtdIns-3-kinase C2 beta) (PI3K-C2beta) (C2-PI3K).

SOS2_HUMAN
θ value	2.36792 (rank : 150)	NC score	0.038554 (rank : 191)
Query Neighborhood Hits	233	Target Neighborhood Hits	193	Shared Neighborhood Hits	25
SwissProt Accessions	Q07890, Q15503	Gene names	SOS2
Domain Architecture
Description	Son of sevenless homolog 2 (SOS-2).

ST5_MOUSE
θ value	2.36792 (rank : 151)	NC score	0.018243 (rank : 247)
Query Neighborhood Hits	233	Target Neighborhood Hits	126	Shared Neighborhood Hits	10
SwissProt Accessions	Q924W7, Q78H54, Q8K2P3, Q924W8	Gene names	St5, Dennd2b
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (DENN domain-containing protein 2B).

UN119_HUMAN
θ value	2.36792 (rank : 152)	NC score	0.026957 (rank : 228)
Query Neighborhood Hits	233	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q13432, O95126	Gene names	UNC119, RG4
Domain Architecture
Description	Unc-119 protein homolog (Retinal protein 4) (HRG4).

WASF2_HUMAN
θ value	2.36792 (rank : 153)	NC score	0.066190 (rank : 111)
Query Neighborhood Hits	233	Target Neighborhood Hits	280	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

WIRE_HUMAN
θ value	2.36792 (rank : 154)	NC score	0.077119 (rank : 82)
Query Neighborhood Hits	233	Target Neighborhood Hits	329	Shared Neighborhood Hits	39
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

WIRE_MOUSE
θ value	2.36792 (rank : 155)	NC score	0.063648 (rank : 118)
Query Neighborhood Hits	233	Target Neighborhood Hits	310	Shared Neighborhood Hits	35
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

ZYX_HUMAN
θ value	2.36792 (rank : 156)	NC score	0.033565 (rank : 211)
Query Neighborhood Hits	233	Target Neighborhood Hits	387	Shared Neighborhood Hits	28
SwissProt Accessions	Q15942	Gene names	ZYX
Domain Architecture
Description	Zyxin (Zyxin-2).

MEF2A_MOUSE
θ value	3.0926 (rank : 157)	NC score	0.013379 (rank : 254)
Query Neighborhood Hits	233	Target Neighborhood Hits	56	Shared Neighborhood Hits	5
SwissProt Accessions	Q60929	Gene names	Mef2a
Domain Architecture
Description	Myocyte-specific enhancer factor 2A.

PHF3_HUMAN
θ value	3.0926 (rank : 158)	NC score	0.035861 (rank : 204)
Query Neighborhood Hits	233	Target Neighborhood Hits	419	Shared Neighborhood Hits	20
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

PRG4_HUMAN
θ value	3.0926 (rank : 159)	NC score	0.063048 (rank : 120)
Query Neighborhood Hits	233	Target Neighborhood Hits	764	Shared Neighborhood Hits	46
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

RASA2_HUMAN
θ value	3.0926 (rank : 160)	NC score	0.085218 (rank : 69)
Query Neighborhood Hits	233	Target Neighborhood Hits	157	Shared Neighborhood Hits	30
SwissProt Accessions	Q15283, O00695, Q15284, Q92594, Q99577, Q9UEQ2	Gene names	RASA2, GAP1M, RASGAP
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

SCAM3_HUMAN
θ value	3.0926 (rank : 161)	NC score	0.022544 (rank : 240)
Query Neighborhood Hits	233	Target Neighborhood Hits	29	Shared Neighborhood Hits	6
SwissProt Accessions	O14828, O15128, Q96FR8, Q9BPY0	Gene names	SCAMP3, PROPIN1
Domain Architecture
Description	Secretory carrier-associated membrane protein 3 (Secretory carrier membrane protein 3).

SF3A2_MOUSE
θ value	3.0926 (rank : 162)	NC score	0.060104 (rank : 125)
Query Neighborhood Hits	233	Target Neighborhood Hits	247	Shared Neighborhood Hits	27
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SHAN1_HUMAN
θ value	3.0926 (rank : 163)	NC score	0.043064 (rank : 180)
Query Neighborhood Hits	233	Target Neighborhood Hits	1041	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

WASF2_MOUSE
θ value	3.0926 (rank : 164)	NC score	0.066204 (rank : 110)
Query Neighborhood Hits	233	Target Neighborhood Hits	315	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

AF17_HUMAN
θ value	4.03905 (rank : 165)	NC score	0.024533 (rank : 236)
Query Neighborhood Hits	233	Target Neighborhood Hits	230	Shared Neighborhood Hits	18
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

BCL6_MOUSE
θ value	4.03905 (rank : 166)	NC score	-0.000698 (rank : 278)
Query Neighborhood Hits	233	Target Neighborhood Hits	913	Shared Neighborhood Hits	26
SwissProt Accessions	P41183, Q61065	Gene names	Bcl6, Bcl-6
Domain Architecture
Description	B-cell lymphoma 6 protein homolog.

BLNK_HUMAN
θ value	4.03905 (rank : 167)	NC score	0.059991 (rank : 126)
Query Neighborhood Hits	233	Target Neighborhood Hits	228	Shared Neighborhood Hits	32
SwissProt Accessions	Q8WV28, O75498, O75499	Gene names	BLNK, BASH, SLP65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (SLP-65).

C43BP_MOUSE
θ value	4.03905 (rank : 168)	NC score	0.099643 (rank : 58)
Query Neighborhood Hits	233	Target Neighborhood Hits	91	Shared Neighborhood Hits	45
SwissProt Accessions	Q9EQG9, Q91WB1, Q9CU52, Q9EQG8	Gene names	Col4a3bp, Stard11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

CEND1_MOUSE
θ value	4.03905 (rank : 169)	NC score	0.081704 (rank : 73)
Query Neighborhood Hits	233	Target Neighborhood Hits	260	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

CYH1_HUMAN
θ value	4.03905 (rank : 170)	NC score	0.083445 (rank : 70)
Query Neighborhood Hits	233	Target Neighborhood Hits	184	Shared Neighborhood Hits	51
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

EGR2_HUMAN
θ value	4.03905 (rank : 171)	NC score	0.002769 (rank : 277)
Query Neighborhood Hits	233	Target Neighborhood Hits	728	Shared Neighborhood Hits	9
SwissProt Accessions	P11161, Q8IV26, Q9UNA6	Gene names	EGR2, KROX20
Domain Architecture	No domain graphic available
Description	Early growth response protein 2 (EGR-2) (Krox-20 protein) (AT591).

NECD_MOUSE
θ value	4.03905 (rank : 172)	NC score	0.017674 (rank : 248)
Query Neighborhood Hits	233	Target Neighborhood Hits	85	Shared Neighborhood Hits	13
SwissProt Accessions	P25233, Q542W7, Q61951	Gene names	Ndn
Domain Architecture
Description	Necdin.

PDCD7_HUMAN
θ value	4.03905 (rank : 173)	NC score	0.042523 (rank : 182)
Query Neighborhood Hits	233	Target Neighborhood Hits	255	Shared Neighborhood Hits	16
SwissProt Accessions	Q8N8D1, Q96AK8, Q9Y6D7	Gene names	PDCD7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18) (HES18).

SAFB2_HUMAN
θ value	4.03905 (rank : 174)	NC score	0.013494 (rank : 253)
Query Neighborhood Hits	233	Target Neighborhood Hits	720	Shared Neighborhood Hits	20
SwissProt Accessions	Q14151, Q8TB13	Gene names	SAFB2, KIAA0138
Domain Architecture
Description	Scaffold attachment factor B2.

SMR1_MOUSE
θ value	4.03905 (rank : 175)	NC score	0.042272 (rank : 184)
Query Neighborhood Hits	233	Target Neighborhood Hits	103	Shared Neighborhood Hits	15
SwissProt Accessions	Q61900	Gene names	Smr1, Msg1
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 1 precursor (Salivary protein MSG1).

TCRG1_HUMAN
θ value	4.03905 (rank : 176)	NC score	0.033734 (rank : 209)
Query Neighborhood Hits	233	Target Neighborhood Hits	929	Shared Neighborhood Hits	42
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TGON2_HUMAN
θ value	4.03905 (rank : 177)	NC score	0.047099 (rank : 171)
Query Neighborhood Hits	233	Target Neighborhood Hits	1037	Shared Neighborhood Hits	71
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

WASF1_MOUSE
θ value	4.03905 (rank : 178)	NC score	0.068380 (rank : 104)
Query Neighborhood Hits	233	Target Neighborhood Hits	261	Shared Neighborhood Hits	31
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

WASP_HUMAN
θ value	4.03905 (rank : 179)	NC score	0.048605 (rank : 165)
Query Neighborhood Hits	233	Target Neighborhood Hits	195	Shared Neighborhood Hits	21
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

ANR38_HUMAN
θ value	5.27518 (rank : 180)	NC score	0.009455 (rank : 263)
Query Neighborhood Hits	233	Target Neighborhood Hits	443	Shared Neighborhood Hits	19
SwissProt Accessions	Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3	Gene names	ANKRD38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

BNIP3_HUMAN
θ value	5.27518 (rank : 181)	NC score	0.017062 (rank : 249)
Query Neighborhood Hits	233	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q12983, O14620, Q96GP0	Gene names	BNIP3, NIP3
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3.

BOC_MOUSE
θ value	5.27518 (rank : 182)	NC score	0.006514 (rank : 272)
Query Neighborhood Hits	233	Target Neighborhood Hits	433	Shared Neighborhood Hits	10
SwissProt Accessions	Q6AZB0, Q6KAM5, Q6P5H3, Q7TMJ3, Q8CE73, Q8CE91, Q8R377, Q923W7	Gene names	Boc
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

BRD4_HUMAN
θ value	5.27518 (rank : 183)	NC score	0.034910 (rank : 207)
Query Neighborhood Hits	233	Target Neighborhood Hits	851	Shared Neighborhood Hits	59
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

BSN_HUMAN
θ value	5.27518 (rank : 184)	NC score	0.059005 (rank : 130)
Query Neighborhood Hits	233	Target Neighborhood Hits	1537	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CE025_HUMAN
θ value	5.27518 (rank : 185)	NC score	0.027022 (rank : 227)
Query Neighborhood Hits	233	Target Neighborhood Hits	114	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NDZ2, Q6NXN8, Q6ZTU4, Q8IZ15	Gene names	C5orf25
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C5orf25.

CTDP1_MOUSE
θ value	5.27518 (rank : 186)	NC score	0.032845 (rank : 212)
Query Neighborhood Hits	233	Target Neighborhood Hits	146	Shared Neighborhood Hits	11
SwissProt Accessions	Q7TSG2, Q7TSS7, Q9D4S8	Gene names	Ctdp1, Fcp1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

ENAH_HUMAN
θ value	5.27518 (rank : 187)	NC score	0.036585 (rank : 200)
Query Neighborhood Hits	233	Target Neighborhood Hits	784	Shared Neighborhood Hits	42
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

PCLO_HUMAN
θ value	5.27518 (rank : 188)	NC score	0.072713 (rank : 92)
Query Neighborhood Hits	233	Target Neighborhood Hits	2046	Shared Neighborhood Hits	137
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

SF3A2_HUMAN
θ value	5.27518 (rank : 189)	NC score	0.053162 (rank : 149)
Query Neighborhood Hits	233	Target Neighborhood Hits	263	Shared Neighborhood Hits	27
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

TITIN_HUMAN
θ value	5.27518 (rank : 190)	NC score	0.011036 (rank : 256)
Query Neighborhood Hits	233	Target Neighborhood Hits	2923	Shared Neighborhood Hits	76
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

ALEX_HUMAN
θ value	6.88961 (rank : 191)	NC score	0.051059 (rank : 155)
Query Neighborhood Hits	233	Target Neighborhood Hits	361	Shared Neighborhood Hits	39
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

BAT3_MOUSE
θ value	6.88961 (rank : 192)	NC score	0.035855 (rank : 205)
Query Neighborhood Hits	233	Target Neighborhood Hits	518	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

BCAR1_HUMAN
θ value	6.88961 (rank : 193)	NC score	0.066903 (rank : 109)
Query Neighborhood Hits	233	Target Neighborhood Hits	554	Shared Neighborhood Hits	74
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

CARD9_HUMAN
θ value	6.88961 (rank : 194)	NC score	0.016053 (rank : 250)
Query Neighborhood Hits	233	Target Neighborhood Hits	602	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H257, Q5SXM6, Q9H854	Gene names	CARD9
Domain Architecture
Description	Caspase recruitment domain-containing protein 9 (hCARD9).

CD2L7_HUMAN
θ value	6.88961 (rank : 195)	NC score	0.007187 (rank : 269)
Query Neighborhood Hits	233	Target Neighborhood Hits	1275	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

CF055_MOUSE
θ value	6.88961 (rank : 196)	NC score	0.038262 (rank : 193)
Query Neighborhood Hits	233	Target Neighborhood Hits	41	Shared Neighborhood Hits	7
SwissProt Accessions	Q9CR26	Gene names
Domain Architecture
Description	Protein C6orf55 homolog.

CYH1_MOUSE
θ value	6.88961 (rank : 197)	NC score	0.080260 (rank : 76)
Query Neighborhood Hits	233	Target Neighborhood Hits	176	Shared Neighborhood Hits	49
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

DAB2_MOUSE
θ value	6.88961 (rank : 198)	NC score	0.026160 (rank : 231)
Query Neighborhood Hits	233	Target Neighborhood Hits	163	Shared Neighborhood Hits	19
SwissProt Accessions	P98078, Q3U3K1, Q91W56, Q923E1	Gene names	Dab2, Doc2
Domain Architecture
Description	Disabled homolog 2 (DOC-2) (Mitogen-responsive phosphoprotein).

DDEF1_MOUSE
θ value	6.88961 (rank : 199)	NC score	0.048364 (rank : 167)
Query Neighborhood Hits	233	Target Neighborhood Hits	592	Shared Neighborhood Hits	60
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

DTX2_MOUSE
θ value	6.88961 (rank : 200)	NC score	0.009463 (rank : 262)
Query Neighborhood Hits	233	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R3P2, Q9CZV3, Q9ER07, Q9ER08	Gene names	Dtx2
Domain Architecture
Description	Protein deltex-2 (Deltex-2) (Deltex2) (mDTX2).

ERRFI_MOUSE
θ value	6.88961 (rank : 201)	NC score	0.044548 (rank : 177)
Query Neighborhood Hits	233	Target Neighborhood Hits	72	Shared Neighborhood Hits	20
SwissProt Accessions	Q99JZ7	Gene names	Errfi1, Mig6
Domain Architecture	No domain graphic available
Description	ERBB receptor feedback inhibitor 1 (Mitogen-inducible gene 6 protein homolog) (Mig-6).

GA2L2_MOUSE
θ value	6.88961 (rank : 202)	NC score	0.045718 (rank : 174)
Query Neighborhood Hits	233	Target Neighborhood Hits	395	Shared Neighborhood Hits	66
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

GPR64_MOUSE
θ value	6.88961 (rank : 203)	NC score	0.010533 (rank : 258)
Query Neighborhood Hits	233	Target Neighborhood Hits	156	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CJ12, Q8BL10, Q8CJ08, Q8CJ09, Q8CJ10	Gene names	Gpr64, Me6
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (Me6 receptor).

HDAC9_MOUSE
θ value	6.88961 (rank : 204)	NC score	0.013658 (rank : 252)
Query Neighborhood Hits	233	Target Neighborhood Hits	186	Shared Neighborhood Hits	7
SwissProt Accessions	Q99N13, Q9EPT2	Gene names	Hdac9, Hdac7b, Hdrp, Mitr
Domain Architecture	No domain graphic available
Description	Histone deacetylase 9 (HD9) (HD7B) (Histone deacetylase-related protein) (MEF2-interacting transcription repressor MITR).

MINT_MOUSE
θ value	6.88961 (rank : 205)	NC score	0.055955 (rank : 136)
Query Neighborhood Hits	233	Target Neighborhood Hits	1514	Shared Neighborhood Hits	109
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MLL4_HUMAN
θ value	6.88961 (rank : 206)	NC score	0.038341 (rank : 192)
Query Neighborhood Hits	233	Target Neighborhood Hits	722	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

MYCB2_HUMAN
θ value	6.88961 (rank : 207)	NC score	0.029730 (rank : 218)
Query Neighborhood Hits	233	Target Neighborhood Hits	390	Shared Neighborhood Hits	28
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

OSBP2_MOUSE
θ value	6.88961 (rank : 208)	NC score	0.055746 (rank : 138)
Query Neighborhood Hits	233	Target Neighborhood Hits	150	Shared Neighborhood Hits	40
SwissProt Accessions	Q5QNQ6, Q8CF21	Gene names	Osbp2
Domain Architecture	No domain graphic available
Description	Oxysterol-binding protein 2.

PDC6I_MOUSE
θ value	6.88961 (rank : 209)	NC score	0.027804 (rank : 225)
Query Neighborhood Hits	233	Target Neighborhood Hits	275	Shared Neighborhood Hits	23
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

PKHA4_HUMAN
θ value	6.88961 (rank : 210)	NC score	0.119184 (rank : 40)
Query Neighborhood Hits	233	Target Neighborhood Hits	283	Shared Neighborhood Hits	63
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PKHA4_MOUSE
θ value	6.88961 (rank : 211)	NC score	0.121147 (rank : 38)
Query Neighborhood Hits	233	Target Neighborhood Hits	202	Shared Neighborhood Hits	47
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

RERE_MOUSE
θ value	6.88961 (rank : 212)	NC score	0.036889 (rank : 198)
Query Neighborhood Hits	233	Target Neighborhood Hits	785	Shared Neighborhood Hits	59
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

TAF3_HUMAN
θ value	6.88961 (rank : 213)	NC score	0.039123 (rank : 190)
Query Neighborhood Hits	233	Target Neighborhood Hits	568	Shared Neighborhood Hits	36
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TCF20_MOUSE
θ value	6.88961 (rank : 214)	NC score	0.038175 (rank : 194)
Query Neighborhood Hits	233	Target Neighborhood Hits	396	Shared Neighborhood Hits	27
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

UBP51_HUMAN
θ value	6.88961 (rank : 215)	NC score	0.006077 (rank : 273)
Query Neighborhood Hits	233	Target Neighborhood Hits	162	Shared Neighborhood Hits	10
SwissProt Accessions	Q70EK9, Q8IWJ8	Gene names	USP51
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51).

ABI3_HUMAN
θ value	8.99809 (rank : 216)	NC score	0.021422 (rank : 244)
Query Neighborhood Hits	233	Target Neighborhood Hits	227	Shared Neighborhood Hits	16
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

CJ026_MOUSE
θ value	8.99809 (rank : 217)	NC score	0.024733 (rank : 234)
Query Neighborhood Hits	233	Target Neighborhood Hits	92	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BGW2, Q3TF48, Q3U3M2, Q6PD43, Q8R0W8	Gene names	D19Wsu162e
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C10orf26 homolog.

FA8_MOUSE
θ value	8.99809 (rank : 218)	NC score	0.005335 (rank : 275)
Query Neighborhood Hits	233	Target Neighborhood Hits	100	Shared Neighborhood Hits	6
SwissProt Accessions	Q06194	Gene names	F8, Cf8, F8c
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component).

HCN4_HUMAN
θ value	8.99809 (rank : 219)	NC score	0.009496 (rank : 261)
Query Neighborhood Hits	233	Target Neighborhood Hits	303	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

KSR2_HUMAN
θ value	8.99809 (rank : 220)	NC score	0.006595 (rank : 271)
Query Neighborhood Hits	233	Target Neighborhood Hits	920	Shared Neighborhood Hits	22
SwissProt Accessions	Q6VAB6, Q8N775	Gene names	KSR2
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-2 (hKSR2).

MPP8_HUMAN
θ value	8.99809 (rank : 221)	NC score	0.009435 (rank : 264)
Query Neighborhood Hits	233	Target Neighborhood Hits	948	Shared Neighborhood Hits	28
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

MUC2_HUMAN
θ value	8.99809 (rank : 222)	NC score	0.040684 (rank : 188)
Query Neighborhood Hits	233	Target Neighborhood Hits	906	Shared Neighborhood Hits	39
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

OSBL6_HUMAN
θ value	8.99809 (rank : 223)	NC score	0.035851 (rank : 206)
Query Neighborhood Hits	233	Target Neighborhood Hits	101	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BZF3, Q7Z4Q1, Q96SR1	Gene names	OSBPL6, ORP6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

OSBL6_MOUSE
θ value	8.99809 (rank : 224)	NC score	0.036172 (rank : 203)
Query Neighborhood Hits	233	Target Neighborhood Hits	105	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BXR9, Q8BYW2	Gene names	Osbpl6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

PRR12_HUMAN
θ value	8.99809 (rank : 225)	NC score	0.059141 (rank : 129)
Query Neighborhood Hits	233	Target Neighborhood Hits	460	Shared Neighborhood Hits	38
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

RBBP6_HUMAN
θ value	8.99809 (rank : 226)	NC score	0.033679 (rank : 210)
Query Neighborhood Hits	233	Target Neighborhood Hits	1135	Shared Neighborhood Hits	51
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RBBP6_MOUSE
θ value	8.99809 (rank : 227)	NC score	0.031504 (rank : 215)
Query Neighborhood Hits	233	Target Neighborhood Hits	1014	Shared Neighborhood Hits	45
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

SF3A1_MOUSE
θ value	8.99809 (rank : 228)	NC score	0.021257 (rank : 245)
Query Neighborhood Hits	233	Target Neighborhood Hits	198	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K4Z5, Q8C0M7, Q8C128, Q8C175, Q921T3	Gene names	Sf3a1
Domain Architecture	No domain graphic available
Description	Splicing factor 3 subunit 1 (SF3a120).

SORL_MOUSE
θ value	8.99809 (rank : 229)	NC score	0.009399 (rank : 265)
Query Neighborhood Hits	233	Target Neighborhood Hits	439	Shared Neighborhood Hits	9
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

ST5_HUMAN
θ value	8.99809 (rank : 230)	NC score	0.019555 (rank : 246)
Query Neighborhood Hits	233	Target Neighborhood Hits	151	Shared Neighborhood Hits	14
SwissProt Accessions	P78524, P78523, Q16492, Q7KYY2, Q7KZ12, Q8NE12, Q9BQQ6	Gene names	ST5, DENND2B, HTS1
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (HeLa tumor suppression 1) (DENN domain-containing protein 2B).

STB5L_MOUSE
θ value	8.99809 (rank : 231)	NC score	0.004882 (rank : 276)
Query Neighborhood Hits	233	Target Neighborhood Hits	138	Shared Neighborhood Hits	2
SwissProt Accessions	Q5DQR4, Q3TSM3, Q3UVG2, Q5DQR1, Q5DQR2, Q5DQR3, Q8BS52	Gene names	Stxbp5l, Llgl4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 5-like (Tomosyn-2) (Lethal(2) giant larvae protein homolog 4).

TTP_HUMAN
θ value	8.99809 (rank : 232)	NC score	0.009541 (rank : 260)
Query Neighborhood Hits	233	Target Neighborhood Hits	86	Shared Neighborhood Hits	5
SwissProt Accessions	P26651	Gene names	ZFP36, G0S24, TIS11A, TTP
Domain Architecture
Description	Tristetraproline (TTP) (Zinc finger protein 36 homolog) (Zfp-36) (TIS11A protein) (TIS11) (Growth factor-inducible nuclear protein NUP475) (G0/G1 switch regulatory protein 24).

ZYX_MOUSE
θ value	8.99809 (rank : 233)	NC score	0.025298 (rank : 233)
Query Neighborhood Hits	233	Target Neighborhood Hits	347	Shared Neighborhood Hits	22
SwissProt Accessions	Q62523, P70461	Gene names	Zyx
Domain Architecture
Description	Zyxin.

3BP2_HUMAN
θ value	θ > 10 (rank : 234)	NC score	0.069528 (rank : 102)
Query Neighborhood Hits	233	Target Neighborhood Hits	296	Shared Neighborhood Hits	67
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

3BP2_MOUSE
θ value	θ > 10 (rank : 235)	NC score	0.051984 (rank : 154)
Query Neighborhood Hits	233	Target Neighborhood Hits	142	Shared Neighborhood Hits	28
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

BCAR1_MOUSE
θ value	θ > 10 (rank : 236)	NC score	0.055008 (rank : 141)
Query Neighborhood Hits	233	Target Neighborhood Hits	438	Shared Neighborhood Hits	56
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

BCL9_HUMAN
θ value	θ > 10 (rank : 237)	NC score	0.073664 (rank : 89)
Query Neighborhood Hits	233	Target Neighborhood Hits	1008	Shared Neighborhood Hits	108
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

BCL9_MOUSE
θ value	θ > 10 (rank : 238)	NC score	0.050700 (rank : 156)
Query Neighborhood Hits	233	Target Neighborhood Hits	770	Shared Neighborhood Hits	88
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

BSN_MOUSE
θ value	θ > 10 (rank : 239)	NC score	0.066020 (rank : 112)
Query Neighborhood Hits	233	Target Neighborhood Hits	2057	Shared Neighborhood Hits	124
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

C43BP_HUMAN
θ value	θ > 10 (rank : 240)	NC score	0.076709 (rank : 84)
Query Neighborhood Hits	233	Target Neighborhood Hits	87	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y5P4, Q96Q85, Q96Q88, Q9H2S7, Q9H2S8	Gene names	COL4A3BP, STARD11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

CD2_HUMAN
θ value	θ > 10 (rank : 241)	NC score	0.050218 (rank : 162)
Query Neighborhood Hits	233	Target Neighborhood Hits	504	Shared Neighborhood Hits	78
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

CEL_HUMAN
θ value	θ > 10 (rank : 242)	NC score	0.050665 (rank : 158)
Query Neighborhood Hits	233	Target Neighborhood Hits	896	Shared Neighborhood Hits	95
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

CYH2_HUMAN
θ value	θ > 10 (rank : 243)	NC score	0.071321 (rank : 94)
Query Neighborhood Hits	233	Target Neighborhood Hits	175	Shared Neighborhood Hits	47
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

CYH2_MOUSE
θ value	θ > 10 (rank : 244)	NC score	0.071253 (rank : 95)
Query Neighborhood Hits	233	Target Neighborhood Hits	171	Shared Neighborhood Hits	47
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

CYH3_HUMAN
θ value	θ > 10 (rank : 245)	NC score	0.070366 (rank : 97)
Query Neighborhood Hits	233	Target Neighborhood Hits	137	Shared Neighborhood Hits	46
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

CYH3_MOUSE
θ value	θ > 10 (rank : 246)	NC score	0.075035 (rank : 86)
Query Neighborhood Hits	233	Target Neighborhood Hits	148	Shared Neighborhood Hits	46
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

CYH4_HUMAN
θ value	θ > 10 (rank : 247)	NC score	0.069618 (rank : 101)
Query Neighborhood Hits	233	Target Neighborhood Hits	135	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UIA0, Q5R3F9, Q9UGT6	Gene names	PSCD4, CYT4
Domain Architecture
Description	Cytohesin-4.

CYH4_MOUSE
θ value	θ > 10 (rank : 248)	NC score	0.070006 (rank : 99)
Query Neighborhood Hits	233	Target Neighborhood Hits	134	Shared Neighborhood Hits	44
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

DGKH_HUMAN
θ value	θ > 10 (rank : 249)	NC score	0.050512 (rank : 160)
Query Neighborhood Hits	233	Target Neighborhood Hits	255	Shared Neighborhood Hits	41
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

FA47A_HUMAN
θ value	θ > 10 (rank : 250)	NC score	0.073039 (rank : 90)
Query Neighborhood Hits	233	Target Neighborhood Hits	451	Shared Neighborhood Hits	84
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

FA47B_HUMAN
θ value	θ > 10 (rank : 251)	NC score	0.064553 (rank : 116)
Query Neighborhood Hits	233	Target Neighborhood Hits	431	Shared Neighborhood Hits	81
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

GGN_MOUSE
θ value	θ > 10 (rank : 252)	NC score	0.053201 (rank : 148)
Query Neighborhood Hits	233	Target Neighborhood Hits	311	Shared Neighborhood Hits	29
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

IRS2_HUMAN
θ value	θ > 10 (rank : 253)	NC score	0.114349 (rank : 44)
Query Neighborhood Hits	233	Target Neighborhood Hits	262	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

IRS2_MOUSE
θ value	θ > 10 (rank : 254)	NC score	0.106513 (rank : 52)
Query Neighborhood Hits	233	Target Neighborhood Hits	248	Shared Neighborhood Hits	24
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

K1802_MOUSE
θ value	θ > 10 (rank : 255)	NC score	0.055433 (rank : 140)
Query Neighborhood Hits	233	Target Neighborhood Hits	1596	Shared Neighborhood Hits	105
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MAGE1_HUMAN
θ value	θ > 10 (rank : 256)	NC score	0.059603 (rank : 127)
Query Neighborhood Hits	233	Target Neighborhood Hits	1389	Shared Neighborhood Hits	117
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MDC1_HUMAN
θ value	θ > 10 (rank : 257)	NC score	0.079058 (rank : 78)
Query Neighborhood Hits	233	Target Neighborhood Hits	1446	Shared Neighborhood Hits	101
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MDC1_MOUSE
θ value	θ > 10 (rank : 258)	NC score	0.078262 (rank : 80)
Query Neighborhood Hits	233	Target Neighborhood Hits	998	Shared Neighborhood Hits	92
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MISS_MOUSE
θ value	θ > 10 (rank : 259)	NC score	0.050487 (rank : 161)
Query Neighborhood Hits	233	Target Neighborhood Hits	444	Shared Neighborhood Hits	69
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

MLL3_HUMAN
θ value	θ > 10 (rank : 260)	NC score	0.060346 (rank : 124)
Query Neighborhood Hits	233	Target Neighborhood Hits	1644	Shared Neighborhood Hits	123
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MLL3_MOUSE
θ value	θ > 10 (rank : 261)	NC score	0.058672 (rank : 132)
Query Neighborhood Hits	233	Target Neighborhood Hits	1399	Shared Neighborhood Hits	110
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MTMRD_HUMAN
θ value	θ > 10 (rank : 262)	NC score	0.068585 (rank : 103)
Query Neighborhood Hits	233	Target Neighborhood Hits	135	Shared Neighborhood Hits	35
SwissProt Accessions	Q86WG5, Q3MJF0, Q68DQ3, Q6P459, Q6PJD1, Q7Z325, Q7Z621, Q86VE2, Q96FE2, Q9C097	Gene names	SBF2, CMT4B2, KIAA1766, MTMR13
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 13 (SET-binding factor 2).

MUC7_HUMAN
θ value	θ > 10 (rank : 263)	NC score	0.052082 (rank : 152)
Query Neighborhood Hits	233	Target Neighborhood Hits	538	Shared Neighborhood Hits	34
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

OGFR_HUMAN
θ value	θ > 10 (rank : 264)	NC score	0.060529 (rank : 123)
Query Neighborhood Hits	233	Target Neighborhood Hits	1582	Shared Neighborhood Hits	115
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

OSBP1_HUMAN
θ value	θ > 10 (rank : 265)	NC score	0.056865 (rank : 135)
Query Neighborhood Hits	233	Target Neighborhood Hits	180	Shared Neighborhood Hits	39
SwissProt Accessions	P22059	Gene names	OSBP, OSBP1
Domain Architecture
Description	Oxysterol-binding protein 1.

PKHA6_HUMAN
θ value	θ > 10 (rank : 266)	NC score	0.131355 (rank : 33)
Query Neighborhood Hits	233	Target Neighborhood Hits	556	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA6_MOUSE
θ value	θ > 10 (rank : 267)	NC score	0.142301 (rank : 25)
Query Neighborhood Hits	233	Target Neighborhood Hits	591	Shared Neighborhood Hits	82
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PLEK2_HUMAN
θ value	θ > 10 (rank : 268)	NC score	0.165594 (rank : 23)
Query Neighborhood Hits	233	Target Neighborhood Hits	101	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

PLEK2_MOUSE
θ value	θ > 10 (rank : 269)	NC score	0.165680 (rank : 22)
Query Neighborhood Hits	233	Target Neighborhood Hits	96	Shared Neighborhood Hits	41
SwissProt Accessions	Q9WV52	Gene names	Plek2
Domain Architecture
Description	Pleckstrin-2.

PRRT3_HUMAN
θ value	θ > 10 (rank : 270)	NC score	0.065844 (rank : 114)
Query Neighborhood Hits	233	Target Neighborhood Hits	998	Shared Neighborhood Hits	109
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

PYGO1_HUMAN
θ value	θ > 10 (rank : 271)	NC score	0.054629 (rank : 143)
Query Neighborhood Hits	233	Target Neighborhood Hits	90	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y3Y4	Gene names	PYGO1
Domain Architecture
Description	Pygopus homolog 1.

RASA3_HUMAN
θ value	θ > 10 (rank : 272)	NC score	0.058085 (rank : 133)
Query Neighborhood Hits	233	Target Neighborhood Hits	166	Shared Neighborhood Hits	29
SwissProt Accessions	Q14644	Gene names	RASA3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein).

RASA3_MOUSE
θ value	θ > 10 (rank : 273)	NC score	0.055694 (rank : 139)
Query Neighborhood Hits	233	Target Neighborhood Hits	144	Shared Neighborhood Hits	26
SwissProt Accessions	Q60790	Gene names	Rasa3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein) (GapIII).

RGS3_MOUSE
θ value	θ > 10 (rank : 274)	NC score	0.061372 (rank : 122)
Query Neighborhood Hits	233	Target Neighborhood Hits	1621	Shared Neighborhood Hits	134
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

RTP3_MOUSE
θ value	θ > 10 (rank : 275)	NC score	0.053884 (rank : 145)
Query Neighborhood Hits	233	Target Neighborhood Hits	374	Shared Neighborhood Hits	67
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

SON_HUMAN
θ value	θ > 10 (rank : 276)	NC score	0.064044 (rank : 117)
Query Neighborhood Hits	233	Target Neighborhood Hits	1568	Shared Neighborhood Hits	131
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

SRRM2_MOUSE
θ value	θ > 10 (rank : 277)	NC score	0.110962 (rank : 48)
Query Neighborhood Hits	233	Target Neighborhood Hits	1470	Shared Neighborhood Hits	105
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TBCD2_HUMAN
θ value	θ > 10 (rank : 278)	NC score	0.079708 (rank : 77)
Query Neighborhood Hits	233	Target Neighborhood Hits	419	Shared Neighborhood Hits	44
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

Hits sorted by NC score

GAB1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	233	Target Neighborhood Hits	233	Shared Neighborhood Hits	233
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

GAB1_HUMAN
NC score	0.963534 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	233	Target Neighborhood Hits	279	Shared Neighborhood Hits	163
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

GAB2_HUMAN
NC score	0.884019 (rank : 3)	θ value	1.21547e-113 (rank : 3)
Query Neighborhood Hits	233	Target Neighborhood Hits	188	Shared Neighborhood Hits	69
SwissProt Accessions	Q9UQC2, O60317	Gene names	GAB2, KIAA0571
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (pp100).

GAB2_MOUSE
NC score	0.872651 (rank : 4)	θ value	2.70778e-113 (rank : 4)
Query Neighborhood Hits	233	Target Neighborhood Hits	220	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

PKHA1_MOUSE
NC score	0.383374 (rank : 5)	θ value	3.08544e-08 (rank : 5)
Query Neighborhood Hits	233	Target Neighborhood Hits	120	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA1_HUMAN
NC score	0.369785 (rank : 6)	θ value	1.29631e-06 (rank : 7)
Query Neighborhood Hits	233	Target Neighborhood Hits	127	Shared Neighborhood Hits	52
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA2_HUMAN
NC score	0.355330 (rank : 7)	θ value	1.87187e-05 (rank : 10)
Query Neighborhood Hits	233	Target Neighborhood Hits	119	Shared Neighborhood Hits	45
SwissProt Accessions	Q9HB19	Gene names	PLEKHA2, TAPP2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2).

PKHA2_MOUSE
NC score	0.351647 (rank : 8)	θ value	1.09739e-05 (rank : 8)
Query Neighborhood Hits	233	Target Neighborhood Hits	116	Shared Neighborhood Hits	45
SwissProt Accessions	Q9ERS5, Q8BY29	Gene names	Plekha2, Tapp2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2) (PH domain-containing adaptor PHAD47).

PLEK_HUMAN
NC score	0.289000 (rank : 9)	θ value	0.000121331 (rank : 14)
Query Neighborhood Hits	233	Target Neighborhood Hits	110	Shared Neighborhood Hits	43
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

PLEK_MOUSE
NC score	0.281719 (rank : 10)	θ value	0.000270298 (rank : 16)
Query Neighborhood Hits	233	Target Neighborhood Hits	109	Shared Neighborhood Hits	41
SwissProt Accessions	Q9JHK5, Q9ERI9	Gene names	Plek
Domain Architecture
Description	Pleckstrin.

DAPP1_MOUSE
NC score	0.231517 (rank : 11)	θ value	0.00134147 (rank : 20)
Query Neighborhood Hits	233	Target Neighborhood Hits	225	Shared Neighborhood Hits	50
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DAPP1_HUMAN
NC score	0.229550 (rank : 12)	θ value	0.00175202 (rank : 21)
Query Neighborhood Hits	233	Target Neighborhood Hits	227	Shared Neighborhood Hits	48
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

CNKR1_HUMAN
NC score	0.225241 (rank : 13)	θ value	0.00298849 (rank : 26)
Query Neighborhood Hits	233	Target Neighborhood Hits	154	Shared Neighborhood Hits	40
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

CNKR2_MOUSE
NC score	0.223244 (rank : 14)	θ value	0.000786445 (rank : 18)
Query Neighborhood Hits	233	Target Neighborhood Hits	197	Shared Neighborhood Hits	37
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_HUMAN
NC score	0.223118 (rank : 15)	θ value	0.000786445 (rank : 17)
Query Neighborhood Hits	233	Target Neighborhood Hits	197	Shared Neighborhood Hits	37
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

PHLB1_MOUSE
NC score	0.221872 (rank : 16)	θ value	0.000270298 (rank : 15)
Query Neighborhood Hits	233	Target Neighborhood Hits	678	Shared Neighborhood Hits	64
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

IRS1_HUMAN
NC score	0.215390 (rank : 17)	θ value	9.29e-05 (rank : 12)
Query Neighborhood Hits	233	Target Neighborhood Hits	109	Shared Neighborhood Hits	18
SwissProt Accessions	P35568	Gene names	IRS1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

IRS1_MOUSE
NC score	0.209796 (rank : 18)	θ value	9.29e-05 (rank : 13)
Query Neighborhood Hits	233	Target Neighborhood Hits	112	Shared Neighborhood Hits	19
SwissProt Accessions	P35569	Gene names	Irs1, Irs-1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

PHLB1_HUMAN
NC score	0.201103 (rank : 19)	θ value	0.000786445 (rank : 19)
Query Neighborhood Hits	233	Target Neighborhood Hits	1038	Shared Neighborhood Hits	96
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PHLB2_HUMAN
NC score	0.177518 (rank : 20)	θ value	2.44474e-05 (rank : 11)
Query Neighborhood Hits	233	Target Neighborhood Hits	964	Shared Neighborhood Hits	50
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

PHLB2_MOUSE
NC score	0.175351 (rank : 21)	θ value	1.87187e-05 (rank : 9)
Query Neighborhood Hits	233	Target Neighborhood Hits	1016	Shared Neighborhood Hits	55
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

PLEK2_MOUSE
NC score	0.165680 (rank : 22)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	233	Target Neighborhood Hits	96	Shared Neighborhood Hits	41
SwissProt Accessions	Q9WV52	Gene names	Plek2
Domain Architecture
Description	Pleckstrin-2.

PLEK2_HUMAN
NC score	0.165594 (rank : 23)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	233	Target Neighborhood Hits	101	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

PKHA5_HUMAN
NC score	0.151860 (rank : 24)	θ value	0.21417 (rank : 59)
Query Neighborhood Hits	233	Target Neighborhood Hits	455	Shared Neighborhood Hits	57
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

PKHA6_MOUSE
NC score	0.142301 (rank : 25)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	233	Target Neighborhood Hits	591	Shared Neighborhood Hits	82
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

TARSH_HUMAN
NC score	0.139623 (rank : 26)	θ value	0.00175202 (rank : 24)
Query Neighborhood Hits	233	Target Neighborhood Hits	768	Shared Neighborhood Hits	102
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

RPB1_MOUSE
NC score	0.136795 (rank : 27)	θ value	0.00175202 (rank : 23)
Query Neighborhood Hits	233	Target Neighborhood Hits	363	Shared Neighborhood Hits	27
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_HUMAN
NC score	0.136578 (rank : 28)	θ value	0.00175202 (rank : 22)
Query Neighborhood Hits	233	Target Neighborhood Hits	362	Shared Neighborhood Hits	27
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

MRIP_HUMAN
NC score	0.136177 (rank : 29)	θ value	0.0563607 (rank : 39)
Query Neighborhood Hits	233	Target Neighborhood Hits	578	Shared Neighborhood Hits	45
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

TARA_MOUSE
NC score	0.133521 (rank : 30)	θ value	0.21417 (rank : 62)
Query Neighborhood Hits	233	Target Neighborhood Hits	1133	Shared Neighborhood Hits	97
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

SRRM2_HUMAN
NC score	0.131941 (rank : 31)	θ value	0.0193708 (rank : 30)
Query Neighborhood Hits	233	Target Neighborhood Hits	1296	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

RAPH1_HUMAN
NC score	0.131895 (rank : 32)	θ value	0.00869519 (rank : 27)
Query Neighborhood Hits	233	Target Neighborhood Hits	593	Shared Neighborhood Hits	67
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

PKHA6_HUMAN
NC score	0.131355 (rank : 33)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	233	Target Neighborhood Hits	556	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

TARA_HUMAN
NC score	0.127942 (rank : 34)	θ value	0.0736092 (rank : 44)
Query Neighborhood Hits	233	Target Neighborhood Hits	1626	Shared Neighborhood Hits	122
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

RHG25_HUMAN
NC score	0.125973 (rank : 35)	θ value	0.125558 (rank : 49)
Query Neighborhood Hits	233	Target Neighborhood Hits	550	Shared Neighborhood Hits	57
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

MRIP_MOUSE
NC score	0.125515 (rank : 36)	θ value	1.06291 (rank : 102)
Query Neighborhood Hits	233	Target Neighborhood Hits	569	Shared Neighborhood Hits	47
SwissProt Accessions	P97434, Q3TBR5, Q3TC85, Q3TRS0, Q3U1Y8, Q3U3E4, Q5SWZ3, Q5SWZ4, Q5SWZ7, Q6P559, Q80YC8	Gene names	Mrip, Kiaa0864, Rhoip3
Domain Architecture
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (p116Rip) (RIP3).

SRRM1_MOUSE
NC score	0.122403 (rank : 37)	θ value	0.0563607 (rank : 40)
Query Neighborhood Hits	233	Target Neighborhood Hits	966	Shared Neighborhood Hits	79
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

PKHA4_MOUSE
NC score	0.121147 (rank : 38)	θ value	6.88961 (rank : 211)
Query Neighborhood Hits	233	Target Neighborhood Hits	202	Shared Neighborhood Hits	47
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

DOC10_HUMAN
NC score	0.121136 (rank : 39)	θ value	0.0148317 (rank : 29)
Query Neighborhood Hits	233	Target Neighborhood Hits	88	Shared Neighborhood Hits	21
SwissProt Accessions	Q96BY6, O75178, Q9NW06, Q9NXI8	Gene names	DOCK10, KIAA0694
Domain Architecture
Description	Dedicator of cytokinesis protein 10 (Protein zizimin 3).

PKHA4_HUMAN
NC score	0.119184 (rank : 40)	θ value	6.88961 (rank : 210)
Query Neighborhood Hits	233	Target Neighborhood Hits	283	Shared Neighborhood Hits	63
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

SRRM1_HUMAN
NC score	0.118644 (rank : 41)	θ value	0.0330416 (rank : 34)
Query Neighborhood Hits	233	Target Neighborhood Hits	690	Shared Neighborhood Hits	49
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SWP70_MOUSE
NC score	0.118348 (rank : 42)	θ value	0.0431538 (rank : 36)
Query Neighborhood Hits	233	Target Neighborhood Hits	1097	Shared Neighborhood Hits	63
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SWP70_HUMAN
NC score	0.115797 (rank : 43)	θ value	0.125558 (rank : 50)
Query Neighborhood Hits	233	Target Neighborhood Hits	973	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

IRS2_HUMAN
NC score	0.114349 (rank : 44)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	233	Target Neighborhood Hits	262	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

RASA1_HUMAN
NC score	0.111818 (rank : 45)	θ value	0.47712 (rank : 82)
Query Neighborhood Hits	233	Target Neighborhood Hits	258	Shared Neighborhood Hits	38
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

WASIP_MOUSE
NC score	0.111300 (rank : 46)	θ value	0.62314 (rank : 93)
Query Neighborhood Hits	233	Target Neighborhood Hits	392	Shared Neighborhood Hits	47
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

MYO10_HUMAN
NC score	0.111001 (rank : 47)	θ value	3.41135e-07 (rank : 6)
Query Neighborhood Hits	233	Target Neighborhood Hits	920	Shared Neighborhood Hits	77
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

SRRM2_MOUSE
NC score	0.110962 (rank : 48)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	233	Target Neighborhood Hits	1470	Shared Neighborhood Hits	105
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

CEND1_HUMAN
NC score	0.110588 (rank : 49)	θ value	0.365318 (rank : 68)
Query Neighborhood Hits	233	Target Neighborhood Hits	284	Shared Neighborhood Hits	48
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

DOCK9_MOUSE
NC score	0.109079 (rank : 50)	θ value	0.0563607 (rank : 38)
Query Neighborhood Hits	233	Target Neighborhood Hits	79	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BIK4, Q921Y6	Gene names	Dock9, D14Wsu89e, Kiaa1058
Domain Architecture
Description	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin 1).

RHG25_MOUSE
NC score	0.106742 (rank : 51)	θ value	0.62314 (rank : 90)
Query Neighborhood Hits	233	Target Neighborhood Hits	492	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

IRS2_MOUSE
NC score	0.106513 (rank : 52)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	233	Target Neighborhood Hits	248	Shared Neighborhood Hits	24
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

CEND2_HUMAN
NC score	0.105469 (rank : 53)	θ value	0.125558 (rank : 48)
Query Neighborhood Hits	233	Target Neighborhood Hits	166	Shared Neighborhood Hits	37
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

BTBDC_HUMAN
NC score	0.105297 (rank : 54)	θ value	0.125558 (rank : 47)
Query Neighborhood Hits	233	Target Neighborhood Hits	248	Shared Neighborhood Hits	26
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

RASA2_MOUSE
NC score	0.104109 (rank : 55)	θ value	0.62314 (rank : 89)
Query Neighborhood Hits	233	Target Neighborhood Hits	159	Shared Neighborhood Hits	35
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

LCP2_HUMAN
NC score	0.102491 (rank : 56)	θ value	1.81305 (rank : 127)
Query Neighborhood Hits	233	Target Neighborhood Hits	531	Shared Neighborhood Hits	85
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

NACAM_MOUSE
NC score	0.100554 (rank : 57)	θ value	1.38821 (rank : 115)
Query Neighborhood Hits	233	Target Neighborhood Hits	1866	Shared Neighborhood Hits	125
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

C43BP_MOUSE
NC score	0.099643 (rank : 58)	θ value	4.03905 (rank : 168)
Query Neighborhood Hits	233	Target Neighborhood Hits	91	Shared Neighborhood Hits	45
SwissProt Accessions	Q9EQG9, Q91WB1, Q9CU52, Q9EQG8	Gene names	Col4a3bp, Stard11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

DOCK9_HUMAN
NC score	0.099614 (rank : 59)	θ value	0.21417 (rank : 56)
Query Neighborhood Hits	233	Target Neighborhood Hits	82	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BZ29, Q5JUD4, Q5JUD6, Q5T2Q1, Q5TAN8, Q9BZ25, Q9BZ26, Q9BZ27, Q9BZ28, Q9UPU4	Gene names	DOCK9, KIAA1058
Domain Architecture
Description	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin 1).

CASL_HUMAN
NC score	0.096138 (rank : 60)	θ value	0.00228821 (rank : 25)
Query Neighborhood Hits	233	Target Neighborhood Hits	259	Shared Neighborhood Hits	22
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

CASL_MOUSE
NC score	0.093912 (rank : 61)	θ value	0.0148317 (rank : 28)
Query Neighborhood Hits	233	Target Neighborhood Hits	225	Shared Neighborhood Hits	15
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

MUC1_HUMAN
NC score	0.091367 (rank : 62)	θ value	0.0961366 (rank : 46)
Query Neighborhood Hits	233	Target Neighborhood Hits	975	Shared Neighborhood Hits	103
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

AB1IP_MOUSE
NC score	0.089254 (rank : 63)	θ value	0.21417 (rank : 54)
Query Neighborhood Hits	233	Target Neighborhood Hits	181	Shared Neighborhood Hits	31
SwissProt Accessions	Q8R5A3, O35329, Q8BRU0, Q99KV8	Gene names	Apbb1ip, Prel1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 48).

WASIP_HUMAN
NC score	0.088787 (rank : 64)	θ value	1.38821 (rank : 122)
Query Neighborhood Hits	233	Target Neighborhood Hits	458	Shared Neighborhood Hits	49
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

BLNK_MOUSE
NC score	0.088672 (rank : 65)	θ value	1.38821 (rank : 107)
Query Neighborhood Hits	233	Target Neighborhood Hits	296	Shared Neighborhood Hits	49
SwissProt Accessions	Q9QUN3, O88504	Gene names	Blnk, Bash, Ly57, Slp65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65) (Lymphocyte antigen 57).

NCOA6_HUMAN
NC score	0.088227 (rank : 66)	θ value	2.36792 (rank : 146)
Query Neighborhood Hits	233	Target Neighborhood Hits	1202	Shared Neighborhood Hits	118
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

TMEPA_MOUSE
NC score	0.088013 (rank : 67)	θ value	0.0563607 (rank : 41)
Query Neighborhood Hits	233	Target Neighborhood Hits	46	Shared Neighborhood Hits	18
SwissProt Accessions	Q9D7R2, Q9EQH9	Gene names	Tmepai, N4wbp4
Domain Architecture	No domain graphic available
Description	Transmembrane prostate androgen-induced protein (NEDD4 WW domain- binding protein 4).

MTMR5_HUMAN
NC score	0.086494 (rank : 68)	θ value	2.36792 (rank : 145)
Query Neighborhood Hits	233	Target Neighborhood Hits	141	Shared Neighborhood Hits	30
SwissProt Accessions	O95248, O60228, Q5JXD8, Q5PPM2, Q96GR9, Q9UGB8	Gene names	SBF1, MTMR5
Domain Architecture
Description	SET-binding factor 1 (Sbf1) (Myotubularin-related protein 5).

RASA2_HUMAN
NC score	0.085218 (rank : 69)	θ value	3.0926 (rank : 160)
Query Neighborhood Hits	233	Target Neighborhood Hits	157	Shared Neighborhood Hits	30
SwissProt Accessions	Q15283, O00695, Q15284, Q92594, Q99577, Q9UEQ2	Gene names	RASA2, GAP1M, RASGAP
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

CYH1_HUMAN
NC score	0.083445 (rank : 70)	θ value	4.03905 (rank : 170)
Query Neighborhood Hits	233	Target Neighborhood Hits	184	Shared Neighborhood Hits	51
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

AB1IP_HUMAN
NC score	0.082727 (rank : 71)	θ value	0.163984 (rank : 51)
Query Neighborhood Hits	233	Target Neighborhood Hits	213	Shared Neighborhood Hits	35
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

WASL_MOUSE
NC score	0.082451 (rank : 72)	θ value	0.365318 (rank : 74)
Query Neighborhood Hits	233	Target Neighborhood Hits	339	Shared Neighborhood Hits	36
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

CEND1_MOUSE
NC score	0.081704 (rank : 73)	θ value	4.03905 (rank : 169)
Query Neighborhood Hits	233	Target Neighborhood Hits	260	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

WASF1_HUMAN
NC score	0.081284 (rank : 74)	θ value	0.279714 (rank : 65)
Query Neighborhood Hits	233	Target Neighborhood Hits	260	Shared Neighborhood Hits	31
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

CENB2_HUMAN
NC score	0.080683 (rank : 75)	θ value	0.47712 (rank : 78)
Query Neighborhood Hits	233	Target Neighborhood Hits	425	Shared Neighborhood Hits	46
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

CYH1_MOUSE
NC score	0.080260 (rank : 76)	θ value	6.88961 (rank : 197)
Query Neighborhood Hits	233	Target Neighborhood Hits	176	Shared Neighborhood Hits	49
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

TBCD2_HUMAN
NC score	0.079708 (rank : 77)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	233	Target Neighborhood Hits	419	Shared Neighborhood Hits	44
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

MDC1_HUMAN
NC score	0.079058 (rank : 78)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	233	Target Neighborhood Hits	1446	Shared Neighborhood Hits	101
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

WASF4_HUMAN
NC score	0.079040 (rank : 79)	θ value	0.163984 (rank : 53)
Query Neighborhood Hits	233	Target Neighborhood Hits	282	Shared Neighborhood Hits	35
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

MDC1_MOUSE
NC score	0.078262 (rank : 80)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	233	Target Neighborhood Hits	998	Shared Neighborhood Hits	92
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

WASL_HUMAN
NC score	0.077849 (rank : 81)	θ value	0.62314 (rank : 94)
Query Neighborhood Hits	233	Target Neighborhood Hits	312	Shared Neighborhood Hits	34
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WIRE_HUMAN
NC score	0.077119 (rank : 82)	θ value	2.36792 (rank : 154)
Query Neighborhood Hits	233	Target Neighborhood Hits	329	Shared Neighborhood Hits	39
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

TMEPA_HUMAN
NC score	0.076973 (rank : 83)	θ value	0.365318 (rank : 73)
Query Neighborhood Hits	233	Target Neighborhood Hits	46	Shared Neighborhood Hits	11
SwissProt Accessions	Q969W9, Q5TDR6, Q96B72, Q9UJD3	Gene names	TMEPAI, PMEPA1, STAG1
Domain Architecture
Description	Transmembrane prostate androgen-induced protein (Solid tumor- associated 1 protein).

C43BP_HUMAN
NC score	0.076709 (rank : 84)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	233	Target Neighborhood Hits	87	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y5P4, Q96Q85, Q96Q88, Q9H2S7, Q9H2S8	Gene names	COL4A3BP, STARD11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

CENB1_HUMAN
NC score	0.075325 (rank : 85)	θ value	0.62314 (rank : 85)
Query Neighborhood Hits	233	Target Neighborhood Hits	383	Shared Neighborhood Hits	44
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

CYH3_MOUSE
NC score	0.075035 (rank : 86)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	233	Target Neighborhood Hits	148	Shared Neighborhood Hits	46
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

BAG3_MOUSE
NC score	0.074159 (rank : 87)	θ value	2.36792 (rank : 133)
Query Neighborhood Hits	233	Target Neighborhood Hits	513	Shared Neighborhood Hits	81
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

UBP2L_HUMAN
NC score	0.073859 (rank : 88)	θ value	0.47712 (rank : 84)
Query Neighborhood Hits	233	Target Neighborhood Hits	170	Shared Neighborhood Hits	20
SwissProt Accessions	Q14157, Q5VU75, Q5VU76, Q9BTU3, Q9UGL5	Gene names	UBAP2L, KIAA0144, NICE4
Domain Architecture
Description	Ubiquitin-associated protein 2-like (Protein NICE-4).

BCL9_HUMAN
NC score	0.073664 (rank : 89)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	233	Target Neighborhood Hits	1008	Shared Neighborhood Hits	108
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

FA47A_HUMAN
NC score	0.073039 (rank : 90)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	233	Target Neighborhood Hits	451	Shared Neighborhood Hits	84
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

CENB5_HUMAN
NC score	0.072766 (rank : 91)	θ value	0.813845 (rank : 95)
Query Neighborhood Hits	233	Target Neighborhood Hits	395	Shared Neighborhood Hits	46
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

PCLO_HUMAN
NC score	0.072713 (rank : 92)	θ value	5.27518 (rank : 188)
Query Neighborhood Hits	233	Target Neighborhood Hits	2046	Shared Neighborhood Hits	137
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

RNC_HUMAN
NC score	0.071616 (rank : 93)	θ value	0.279714 (rank : 64)
Query Neighborhood Hits	233	Target Neighborhood Hits	176	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NRR4, Q7Z5V2, Q86YH0, Q9NW73, Q9Y2V9, Q9Y4Y0	Gene names	RNASEN, RN3, RNASE3L
Domain Architecture
Description	Ribonuclease III (EC 3.1.26.3) (RNase III) (Drosha) (p241).

CYH2_HUMAN
NC score	0.071321 (rank : 94)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	233	Target Neighborhood Hits	175	Shared Neighborhood Hits	47
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

CYH2_MOUSE
NC score	0.071253 (rank : 95)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	233	Target Neighborhood Hits	171	Shared Neighborhood Hits	47
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

PRG4_MOUSE
NC score	0.070900 (rank : 96)	θ value	0.0252991 (rank : 32)
Query Neighborhood Hits	233	Target Neighborhood Hits	624	Shared Neighborhood Hits	41
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

CYH3_HUMAN
NC score	0.070366 (rank : 97)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	233	Target Neighborhood Hits	137	Shared Neighborhood Hits	46
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

CR001_HUMAN
NC score	0.070299 (rank : 98)	θ value	0.62314 (rank : 86)
Query Neighborhood Hits	233	Target Neighborhood Hits	68	Shared Neighborhood Hits	10
SwissProt Accessions	O15165, O15166, O15167, O15168, Q6NXP3	Gene names	C18orf1
Domain Architecture
Description	Protein C18orf1.

CYH4_MOUSE
NC score	0.070006 (rank : 99)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	233	Target Neighborhood Hits	134	Shared Neighborhood Hits	44
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

CR001_MOUSE
NC score	0.069827 (rank : 100)	θ value	0.62314 (rank : 87)
Query Neighborhood Hits	233	Target Neighborhood Hits	67	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BWJ4	Gene names	D18Ertd653e
Domain Architecture	No domain graphic available
Description	Protein C18orf1 homolog.

CYH4_HUMAN
NC score	0.069618 (rank : 101)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	233	Target Neighborhood Hits	135	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UIA0, Q5R3F9, Q9UGT6	Gene names	PSCD4, CYT4
Domain Architecture
Description	Cytohesin-4.

3BP2_HUMAN
NC score	0.069528 (rank : 102)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	233	Target Neighborhood Hits	296	Shared Neighborhood Hits	67
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

MTMRD_HUMAN
NC score	0.068585 (rank : 103)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	233	Target Neighborhood Hits	135	Shared Neighborhood Hits	35
SwissProt Accessions	Q86WG5, Q3MJF0, Q68DQ3, Q6P459, Q6PJD1, Q7Z325, Q7Z621, Q86VE2, Q96FE2, Q9C097	Gene names	SBF2, CMT4B2, KIAA1766, MTMR13
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 13 (SET-binding factor 2).

WASF1_MOUSE
NC score	0.068380 (rank : 104)	θ value	4.03905 (rank : 178)
Query Neighborhood Hits	233	Target Neighborhood Hits	261	Shared Neighborhood Hits	31
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

GSCR1_HUMAN
NC score	0.067736 (rank : 105)	θ value	1.38821 (rank : 113)
Query Neighborhood Hits	233	Target Neighborhood Hits	674	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

ZIM10_HUMAN
NC score	0.067287 (rank : 106)	θ value	1.38821 (rank : 123)
Query Neighborhood Hits	233	Target Neighborhood Hits	577	Shared Neighborhood Hits	78
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

RBM16_HUMAN
NC score	0.067179 (rank : 107)	θ value	0.21417 (rank : 60)
Query Neighborhood Hits	233	Target Neighborhood Hits	300	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UPN6, Q5TBU6, Q9BQN8, Q9BX43	Gene names	RBM16, KIAA1116
Domain Architecture
Description	Putative RNA-binding protein 16 (RNA-binding motif protein 16).

NCOA6_MOUSE
NC score	0.067105 (rank : 108)	θ value	2.36792 (rank : 147)
Query Neighborhood Hits	233	Target Neighborhood Hits	1076	Shared Neighborhood Hits	102
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

BCAR1_HUMAN
NC score	0.066903 (rank : 109)	θ value	6.88961 (rank : 193)
Query Neighborhood Hits	233	Target Neighborhood Hits	554	Shared Neighborhood Hits	74
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

WASF2_MOUSE
NC score	0.066204 (rank : 110)	θ value	3.0926 (rank : 164)
Query Neighborhood Hits	233	Target Neighborhood Hits	315	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

WASF2_HUMAN
NC score	0.066190 (rank : 111)	θ value	2.36792 (rank : 153)
Query Neighborhood Hits	233	Target Neighborhood Hits	280	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

BSN_MOUSE
NC score	0.066020 (rank : 112)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	233	Target Neighborhood Hits	2057	Shared Neighborhood Hits	124
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

PDCD7_MOUSE
NC score	0.065884 (rank : 113)	θ value	0.62314 (rank : 88)
Query Neighborhood Hits	233	Target Neighborhood Hits	214	Shared Neighborhood Hits	14
SwissProt Accessions	Q9WTY1, Q8R5D9	Gene names	Pdcd7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18).

PRRT3_HUMAN
NC score	0.065844 (rank : 114)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	233	Target Neighborhood Hits	998	Shared Neighborhood Hits	109
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

MLL2_HUMAN
NC score	0.065334 (rank : 115)	θ value	0.0736092 (rank : 42)
Query Neighborhood Hits	233	Target Neighborhood Hits	1788	Shared Neighborhood Hits	99
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

FA47B_HUMAN
NC score	0.064553 (rank : 116)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	233	Target Neighborhood Hits	431	Shared Neighborhood Hits	81
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

SON_HUMAN
NC score	0.064044 (rank : 117)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	233	Target Neighborhood Hits	1568	Shared Neighborhood Hits	131
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

WIRE_MOUSE
NC score	0.063648 (rank : 118)	θ value	2.36792 (rank : 155)
Query Neighborhood Hits	233	Target Neighborhood Hits	310	Shared Neighborhood Hits	35
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

IWS1_HUMAN
NC score	0.063409 (rank : 119)	θ value	0.0330416 (rank : 33)
Query Neighborhood Hits	233	Target Neighborhood Hits	1241	Shared Neighborhood Hits	62
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

PRG4_HUMAN
NC score	0.063048 (rank : 120)	θ value	3.0926 (rank : 159)
Query Neighborhood Hits	233	Target Neighborhood Hits	764	Shared Neighborhood Hits	46
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PCLO_MOUSE
NC score	0.061863 (rank : 121)	θ value	1.81305 (rank : 131)
Query Neighborhood Hits	233	Target Neighborhood Hits	2275	Shared Neighborhood Hits	129
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

RGS3_MOUSE
NC score	0.061372 (rank : 122)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	233	Target Neighborhood Hits	1621	Shared Neighborhood Hits	134
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

OGFR_HUMAN
NC score	0.060529 (rank : 123)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	233	Target Neighborhood Hits	1582	Shared Neighborhood Hits	115
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

MLL3_HUMAN
NC score	0.060346 (rank : 124)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	233	Target Neighborhood Hits	1644	Shared Neighborhood Hits	123
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

SF3A2_MOUSE
NC score	0.060104 (rank : 125)	θ value	3.0926 (rank : 162)
Query Neighborhood Hits	233	Target Neighborhood Hits	247	Shared Neighborhood Hits	27
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

BLNK_HUMAN
NC score	0.059991 (rank : 126)	θ value	4.03905 (rank : 167)
Query Neighborhood Hits	233	Target Neighborhood Hits	228	Shared Neighborhood Hits	32
SwissProt Accessions	Q8WV28, O75498, O75499	Gene names	BLNK, BASH, SLP65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (SLP-65).

MAGE1_HUMAN
NC score	0.059603 (rank : 127)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	233	Target Neighborhood Hits	1389	Shared Neighborhood Hits	117
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

HNRL1_MOUSE
NC score	0.059384 (rank : 128)	θ value	0.47712 (rank : 80)
Query Neighborhood Hits	233	Target Neighborhood Hits	200	Shared Neighborhood Hits	28
SwissProt Accessions	Q8VDM6, Q3U201, Q3UPB0, Q6AZA7, Q8BY45, Q8K365	Gene names	Hnrpul1
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1.

PRR12_HUMAN
NC score	0.059141 (rank : 129)	θ value	8.99809 (rank : 225)
Query Neighborhood Hits	233	Target Neighborhood Hits	460	Shared Neighborhood Hits	38
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

BSN_HUMAN
NC score	0.059005 (rank : 130)	θ value	5.27518 (rank : 184)
Query Neighborhood Hits	233	Target Neighborhood Hits	1537	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

ZIM10_MOUSE
NC score	0.058984 (rank : 131)	θ value	0.365318 (rank : 75)
Query Neighborhood Hits	233	Target Neighborhood Hits	430	Shared Neighborhood Hits	54
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

MLL3_MOUSE
NC score	0.058672 (rank : 132)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	233	Target Neighborhood Hits	1399	Shared Neighborhood Hits	110
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

RASA3_HUMAN
NC score	0.058085 (rank : 133)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	233	Target Neighborhood Hits	166	Shared Neighborhood Hits	29
SwissProt Accessions	Q14644	Gene names	RASA3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein).

TAF3_MOUSE
NC score	0.057004 (rank : 134)	θ value	0.62314 (rank : 92)
Query Neighborhood Hits	233	Target Neighborhood Hits	463	Shared Neighborhood Hits	32
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

OSBP1_HUMAN
NC score	0.056865 (rank : 135)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	233	Target Neighborhood Hits	180	Shared Neighborhood Hits	39
SwissProt Accessions	P22059	Gene names	OSBP, OSBP1
Domain Architecture
Description	Oxysterol-binding protein 1.

MINT_MOUSE
NC score	0.055955 (rank : 136)	θ value	6.88961 (rank : 205)
Query Neighborhood Hits	233	Target Neighborhood Hits	1514	Shared Neighborhood Hits	109
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

GNAS3_HUMAN
NC score	0.055845 (rank : 137)	θ value	2.36792 (rank : 143)
Query Neighborhood Hits	233	Target Neighborhood Hits	71	Shared Neighborhood Hits	7
SwissProt Accessions	O95467, O95417	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Neuroendocrine secretory protein 55 (NESP55) [Contains: LHAL tetrapeptide; GPIPIRRH peptide].

OSBP2_MOUSE
NC score	0.055746 (rank : 138)	θ value	6.88961 (rank : 208)
Query Neighborhood Hits	233	Target Neighborhood Hits	150	Shared Neighborhood Hits	40
SwissProt Accessions	Q5QNQ6, Q8CF21	Gene names	Osbp2
Domain Architecture	No domain graphic available
Description	Oxysterol-binding protein 2.

RASA3_MOUSE
NC score	0.055694 (rank : 139)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	233	Target Neighborhood Hits	144	Shared Neighborhood Hits	26
SwissProt Accessions	Q60790	Gene names	Rasa3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein) (GapIII).

K1802_MOUSE
NC score	0.055433 (rank : 140)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	233	Target Neighborhood Hits	1596	Shared Neighborhood Hits	105
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

BCAR1_MOUSE
NC score	0.055008 (rank : 141)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	233	Target Neighborhood Hits	438	Shared Neighborhood Hits	56
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

AF9_HUMAN
NC score	0.054951 (rank : 142)	θ value	1.38821 (rank : 106)
Query Neighborhood Hits	233	Target Neighborhood Hits	202	Shared Neighborhood Hits	14
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

PYGO1_HUMAN
NC score	0.054629 (rank : 143)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	233	Target Neighborhood Hits	90	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y3Y4	Gene names	PYGO1
Domain Architecture
Description	Pygopus homolog 1.

HNRL1_HUMAN
NC score	0.054449 (rank : 144)	θ value	0.365318 (rank : 71)
Query Neighborhood Hits	233	Target Neighborhood Hits	173	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BUJ2, O76022, Q6ZSZ0, Q7L8P4, Q8N6Z4, Q96G37, Q9HAL3, Q9UG75	Gene names	HNRPUL1, E1BAP5
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1 (Adenovirus early region 1B-associated protein 5) (E1B-55 kDa-associated protein 5) (E1B-AP5).

RTP3_MOUSE
NC score	0.053884 (rank : 145)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	233	Target Neighborhood Hits	374	Shared Neighborhood Hits	67
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

ZCHC8_MOUSE
NC score	0.053784 (rank : 146)	θ value	0.21417 (rank : 63)
Query Neighborhood Hits	233	Target Neighborhood Hits	134	Shared Neighborhood Hits	13
SwissProt Accessions	Q9CYA6, Q3TK71, Q8CCB7, Q91WQ1	Gene names	Zcchc8
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 8.

LR37A_HUMAN
NC score	0.053432 (rank : 147)	θ value	1.81305 (rank : 128)
Query Neighborhood Hits	233	Target Neighborhood Hits	720	Shared Neighborhood Hits	60
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

GGN_MOUSE
NC score	0.053201 (rank : 148)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	233	Target Neighborhood Hits	311	Shared Neighborhood Hits	29
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

SF3A2_HUMAN
NC score	0.053162 (rank : 149)	θ value	5.27518 (rank : 189)
Query Neighborhood Hits	233	Target Neighborhood Hits	263	Shared Neighborhood Hits	27
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

UBP2L_MOUSE
NC score	0.052691 (rank : 150)	θ value	1.38821 (rank : 121)
Query Neighborhood Hits	233	Target Neighborhood Hits	173	Shared Neighborhood Hits	18
SwissProt Accessions	Q80X50, Q8BIT6, Q8BIW4, Q8BJ01, Q8CIG7, Q8K102, Q9CRT6	Gene names	Ubap2l
Domain Architecture	No domain graphic available
Description	Ubiquitin-associated protein 2-like.

FHOD1_MOUSE
NC score	0.052375 (rank : 151)	θ value	1.06291 (rank : 99)
Query Neighborhood Hits	233	Target Neighborhood Hits	217	Shared Neighborhood Hits	27
SwissProt Accessions	Q6P9Q4, Q8BMK2	Gene names	Fhod1, Fhos1
Domain Architecture	No domain graphic available
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

MUC7_HUMAN
NC score	0.052082 (rank : 152)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	233	Target Neighborhood Hits	538	Shared Neighborhood Hits	34
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

DIAP1_HUMAN
NC score	0.051992 (rank : 153)	θ value	0.365318 (rank : 69)
Query Neighborhood Hits	233	Target Neighborhood Hits	784	Shared Neighborhood Hits	36
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

3BP2_MOUSE
NC score	0.051984 (rank : 154)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	233	Target Neighborhood Hits	142	Shared Neighborhood Hits	28
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

ALEX_HUMAN
NC score	0.051059 (rank : 155)	θ value	6.88961 (rank : 191)
Query Neighborhood Hits	233	Target Neighborhood Hits	361	Shared Neighborhood Hits	39
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

BCL9_MOUSE
NC score	0.050700 (rank : 156)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	233	Target Neighborhood Hits	770	Shared Neighborhood Hits	88
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

BTG3_HUMAN
NC score	0.050668 (rank : 157)	θ value	1.38821 (rank : 109)
Query Neighborhood Hits	233	Target Neighborhood Hits	32	Shared Neighborhood Hits	9
SwissProt Accessions	Q14201, Q96ET7	Gene names	BTG3, ANA, TOB5
Domain Architecture
Description	BTG3 protein (Tob5 protein) (Abundant in neuroepithelium area protein).

CEL_HUMAN
NC score	0.050665 (rank : 158)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	233	Target Neighborhood Hits	896	Shared Neighborhood Hits	95
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

3BP1_HUMAN
NC score	0.050536 (rank : 159)	θ value	1.06291 (rank : 98)
Query Neighborhood Hits	233	Target Neighborhood Hits	376	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

DGKH_HUMAN
NC score	0.050512 (rank : 160)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	233	Target Neighborhood Hits	255	Shared Neighborhood Hits	41
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

MISS_MOUSE
NC score	0.050487 (rank : 161)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	233	Target Neighborhood Hits	444	Shared Neighborhood Hits	69
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

CD2_HUMAN
NC score	0.050218 (rank : 162)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	233	Target Neighborhood Hits	504	Shared Neighborhood Hits	78
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

OSBL3_MOUSE
NC score	0.049166 (rank : 163)	θ value	1.38821 (rank : 116)
Query Neighborhood Hits	233	Target Neighborhood Hits	86	Shared Neighborhood Hits	25
SwissProt Accessions	Q9DBS9	Gene names	Osbpl3, Orp3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

DREB_MOUSE
NC score	0.048909 (rank : 164)	θ value	0.365318 (rank : 70)
Query Neighborhood Hits	233	Target Neighborhood Hits	446	Shared Neighborhood Hits	26
SwissProt Accessions	Q9QXS6, Q922X1, Q9QXS5	Gene names	Dbn1, Drba
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

WASP_HUMAN
NC score	0.048605 (rank : 165)	θ value	4.03905 (rank : 179)
Query Neighborhood Hits	233	Target Neighborhood Hits	195	Shared Neighborhood Hits	21
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

S23IP_HUMAN
NC score	0.048589 (rank : 166)	θ value	0.21417 (rank : 61)
Query Neighborhood Hits	233	Target Neighborhood Hits	134	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y6Y8, Q8IXH5, Q9BUK5	Gene names	SEC23IP
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein (p125).

DDEF1_MOUSE
NC score	0.048364 (rank : 167)	θ value	6.88961 (rank : 199)
Query Neighborhood Hits	233	Target Neighborhood Hits	592	Shared Neighborhood Hits	60
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

OSBL3_HUMAN
NC score	0.048246 (rank : 168)	θ value	1.81305 (rank : 129)
Query Neighborhood Hits	233	Target Neighborhood Hits	93	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H4L5, O14591, O43357, O43358, Q8N702, Q8N703, Q8N704, Q8NFH0, Q8NFH1, Q8NI12, Q8NI13, Q9BZF4, Q9UED6	Gene names	OSBPL3, KIAA0704, ORP3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

CCNK_MOUSE
NC score	0.048097 (rank : 169)	θ value	2.36792 (rank : 136)
Query Neighborhood Hits	233	Target Neighborhood Hits	350	Shared Neighborhood Hits	35
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

MAGC1_HUMAN
NC score	0.047195 (rank : 170)	θ value	2.36792 (rank : 144)
Query Neighborhood Hits	233	Target Neighborhood Hits	431	Shared Neighborhood Hits	40
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

TGON2_HUMAN
NC score	0.047099 (rank : 171)	θ value	4.03905 (rank : 177)
Query Neighborhood Hits	233	Target Neighborhood Hits	1037	Shared Neighborhood Hits	71
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

BRD4_MOUSE
NC score	0.046953 (rank : 172)	θ value	1.38821 (rank : 108)
Query Neighborhood Hits	233	Target Neighborhood Hits	845	Shared Neighborhood Hits	56
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

CT151_HUMAN
NC score	0.045749 (rank : 173)	θ value	1.81305 (rank : 126)
Query Neighborhood Hits	233	Target Neighborhood Hits	382	Shared Neighborhood Hits	31
SwissProt Accessions	Q8NC74, Q8N4Z9, Q9BR75, Q9H0Y9	Gene names	C20orf151
Domain Architecture
Description	Uncharacterized protein C20orf151.

GA2L2_MOUSE
NC score	0.045718 (rank : 174)	θ value	6.88961 (rank : 202)
Query Neighborhood Hits	233	Target Neighborhood Hits	395	Shared Neighborhood Hits	66
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

PYGO2_HUMAN
NC score	0.045068 (rank : 175)	θ value	1.38821 (rank : 119)
Query Neighborhood Hits	233	Target Neighborhood Hits	189	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BRQ0, Q8WYZ4, Q96CY2	Gene names	PYGO2
Domain Architecture
Description	Pygopus homolog 2.

T22D2_HUMAN
NC score	0.044803 (rank : 176)	θ value	1.06291 (rank : 105)
Query Neighborhood Hits	233	Target Neighborhood Hits	250	Shared Neighborhood Hits	20
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

ERRFI_MOUSE
NC score	0.044548 (rank : 177)	θ value	6.88961 (rank : 201)
Query Neighborhood Hits	233	Target Neighborhood Hits	72	Shared Neighborhood Hits	20
SwissProt Accessions	Q99JZ7	Gene names	Errfi1, Mig6
Domain Architecture	No domain graphic available
Description	ERBB receptor feedback inhibitor 1 (Mitogen-inducible gene 6 protein homolog) (Mig-6).

FMN1A_MOUSE
NC score	0.044412 (rank : 178)	θ value	2.36792 (rank : 140)
Query Neighborhood Hits	233	Target Neighborhood Hits	423	Shared Neighborhood Hits	37
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

BTG3_MOUSE
NC score	0.043896 (rank : 179)	θ value	2.36792 (rank : 134)
Query Neighborhood Hits	233	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	P50615, Q62328	Gene names	Btg3, Ana, Tob5
Domain Architecture
Description	BTG3 protein (Tob5 protein) (Abundant in neuroepithelium area protein).

SHAN1_HUMAN
NC score	0.043064 (rank : 180)	θ value	3.0926 (rank : 163)
Query Neighborhood Hits	233	Target Neighborhood Hits	1041	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

R3HD2_MOUSE
NC score	0.042856 (rank : 181)	θ value	1.06291 (rank : 104)
Query Neighborhood Hits	233	Target Neighborhood Hits	397	Shared Neighborhood Hits	37
SwissProt Accessions	Q80TM6, Q80YB1, Q8BLS5, Q9CW50	Gene names	R3hdm2, Kiaa1002
Domain Architecture
Description	R3H domain-containing protein 2.

PDCD7_HUMAN
NC score	0.042523 (rank : 182)	θ value	4.03905 (rank : 173)
Query Neighborhood Hits	233	Target Neighborhood Hits	255	Shared Neighborhood Hits	16
SwissProt Accessions	Q8N8D1, Q96AK8, Q9Y6D7	Gene names	PDCD7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18) (HES18).

FMN1B_MOUSE
NC score	0.042281 (rank : 183)	θ value	2.36792 (rank : 141)
Query Neighborhood Hits	233	Target Neighborhood Hits	447	Shared Neighborhood Hits	33
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

SMR1_MOUSE
NC score	0.042272 (rank : 184)	θ value	4.03905 (rank : 175)
Query Neighborhood Hits	233	Target Neighborhood Hits	103	Shared Neighborhood Hits	15
SwissProt Accessions	Q61900	Gene names	Smr1, Msg1
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 1 precursor (Salivary protein MSG1).

DPOD3_HUMAN
NC score	0.042161 (rank : 185)	θ value	2.36792 (rank : 139)
Query Neighborhood Hits	233	Target Neighborhood Hits	109	Shared Neighborhood Hits	11
SwissProt Accessions	Q15054	Gene names	POLD3, KIAA0039
Domain Architecture	No domain graphic available
Description	DNA polymerase subunit delta 3 (DNA polymerase subunit delta p66).

ZDHC8_HUMAN
NC score	0.041382 (rank : 186)	θ value	0.279714 (rank : 66)
Query Neighborhood Hits	233	Target Neighborhood Hits	234	Shared Neighborhood Hits	27
SwissProt Accessions	Q9ULC8, Q6ICL1, Q6ZNF5, Q7Z6L9	Gene names	ZDHHC8, KIAA1292, ZDHHCL1, ZNF378
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8) (Zinc finger protein 378).

NCOR2_HUMAN
NC score	0.040973 (rank : 187)	θ value	2.36792 (rank : 148)
Query Neighborhood Hits	233	Target Neighborhood Hits	870	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

MUC2_HUMAN
NC score	0.040684 (rank : 188)	θ value	8.99809 (rank : 222)
Query Neighborhood Hits	233	Target Neighborhood Hits	906	Shared Neighborhood Hits	39
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

DYN3_HUMAN
NC score	0.039951 (rank : 189)	θ value	0.47712 (rank : 79)
Query Neighborhood Hits	233	Target Neighborhood Hits	158	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UQ16, O14982, O95555, Q5W129, Q9H0P3, Q9H548, Q9NQ68, Q9NQN6	Gene names	DNM3, KIAA0820
Domain Architecture
Description	Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin).

TAF3_HUMAN
NC score	0.039123 (rank : 190)	θ value	6.88961 (rank : 213)
Query Neighborhood Hits	233	Target Neighborhood Hits	568	Shared Neighborhood Hits	36
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

SOS2_HUMAN
NC score	0.038554 (rank : 191)	θ value	2.36792 (rank : 150)
Query Neighborhood Hits	233	Target Neighborhood Hits	193	Shared Neighborhood Hits	25
SwissProt Accessions	Q07890, Q15503	Gene names	SOS2
Domain Architecture
Description	Son of sevenless homolog 2 (SOS-2).

MLL4_HUMAN
NC score	0.038341 (rank : 192)	θ value	6.88961 (rank : 206)
Query Neighborhood Hits	233	Target Neighborhood Hits	722	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

CF055_MOUSE
NC score	0.038262 (rank : 193)	θ value	6.88961 (rank : 196)
Query Neighborhood Hits	233	Target Neighborhood Hits	41	Shared Neighborhood Hits	7
SwissProt Accessions	Q9CR26	Gene names
Domain Architecture
Description	Protein C6orf55 homolog.

TCF20_MOUSE
NC score	0.038175 (rank : 194)	θ value	6.88961 (rank : 214)
Query Neighborhood Hits	233	Target Neighborhood Hits	396	Shared Neighborhood Hits	27
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

ZDHC8_MOUSE
NC score	0.038160 (rank : 195)	θ value	0.813845 (rank : 97)
Query Neighborhood Hits	233	Target Neighborhood Hits	243	Shared Neighborhood Hits	19
SwissProt Accessions	Q5Y5T5, Q7TNF7	Gene names	Zdhhc8
Domain Architecture	No domain graphic available
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8).

DIAP2_MOUSE
NC score	0.038100 (rank : 196)	θ value	1.38821 (rank : 110)
Query Neighborhood Hits	233	Target Neighborhood Hits	260	Shared Neighborhood Hits	18
SwissProt Accessions	O70566, Q8C2G8	Gene names	Diaph2, Diap2
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2) (mDia3).

CABYR_MOUSE
NC score	0.037819 (rank : 197)	θ value	2.36792 (rank : 135)
Query Neighborhood Hits	233	Target Neighborhood Hits	80	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D424, Q91Y41, Q91Y42	Gene names	Cabyr, Cbp86
Domain Architecture	No domain graphic available
Description	Calcium-binding tyrosine phosphorylation-regulated protein (Calcium- binding protein 86) (Testis-specific calcium-binding protein CBP86).

RERE_MOUSE
NC score	0.036889 (rank : 198)	θ value	6.88961 (rank : 212)
Query Neighborhood Hits	233	Target Neighborhood Hits	785	Shared Neighborhood Hits	59
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

STX5_HUMAN
NC score	0.036830 (rank : 199)	θ value	0.62314 (rank : 91)
Query Neighborhood Hits	233	Target Neighborhood Hits	74	Shared Neighborhood Hits	4
SwissProt Accessions	Q13190, Q5U0D4, Q7Z3T6, Q9BUG1	Gene names	STX5, STX5A
Domain Architecture
Description	Syntaxin-5.

ENAH_HUMAN
NC score	0.036585 (rank : 200)	θ value	5.27518 (rank : 187)
Query Neighborhood Hits	233	Target Neighborhood Hits	784	Shared Neighborhood Hits	42
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

KCT2_MOUSE
NC score	0.036488 (rank : 201)	θ value	1.38821 (rank : 114)
Query Neighborhood Hits	233	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K201, Q5SVC5, Q922L7, Q9CVN1	Gene names	Kct2
Domain Architecture	No domain graphic available
Description	Keratinocytes-associated transmembrane protein 2 precursor.

TCRG1_MOUSE
NC score	0.036310 (rank : 202)	θ value	1.81305 (rank : 132)
Query Neighborhood Hits	233	Target Neighborhood Hits	947	Shared Neighborhood Hits	45
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

OSBL6_MOUSE
NC score	0.036172 (rank : 203)	θ value	8.99809 (rank : 224)
Query Neighborhood Hits	233	Target Neighborhood Hits	105	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BXR9, Q8BYW2	Gene names	Osbpl6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

PHF3_HUMAN
NC score	0.035861 (rank : 204)	θ value	3.0926 (rank : 158)
Query Neighborhood Hits	233	Target Neighborhood Hits	419	Shared Neighborhood Hits	20
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

BAT3_MOUSE
NC score	0.035855 (rank : 205)	θ value	6.88961 (rank : 192)
Query Neighborhood Hits	233	Target Neighborhood Hits	518	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

OSBL6_HUMAN
NC score	0.035851 (rank : 206)	θ value	8.99809 (rank : 223)
Query Neighborhood Hits	233	Target Neighborhood Hits	101	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BZF3, Q7Z4Q1, Q96SR1	Gene names	OSBPL6, ORP6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

BRD4_HUMAN
NC score	0.034910 (rank : 207)	θ value	5.27518 (rank : 183)
Query Neighborhood Hits	233	Target Neighborhood Hits	851	Shared Neighborhood Hits	59
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

DIAP3_HUMAN
NC score	0.033849 (rank : 208)	θ value	1.38821 (rank : 111)
Query Neighborhood Hits	233	Target Neighborhood Hits	209	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NSV4, Q5T2S7, Q5XKF6, Q6MZF0, Q6NUP0, Q86VS4, Q8NAV4	Gene names	DIAPH3, DIAP3
Domain Architecture	No domain graphic available
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3).

TCRG1_HUMAN
NC score	0.033734 (rank : 209)	θ value	4.03905 (rank : 176)
Query Neighborhood Hits	233	Target Neighborhood Hits	929	Shared Neighborhood Hits	42
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

RBBP6_HUMAN
NC score	0.033679 (rank : 210)	θ value	8.99809 (rank : 226)
Query Neighborhood Hits	233	Target Neighborhood Hits	1135	Shared Neighborhood Hits	51
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

ZYX_HUMAN
NC score	0.033565 (rank : 211)	θ value	2.36792 (rank : 156)
Query Neighborhood Hits	233	Target Neighborhood Hits	387	Shared Neighborhood Hits	28
SwissProt Accessions	Q15942	Gene names	ZYX
Domain Architecture
Description	Zyxin (Zyxin-2).

CTDP1_MOUSE
NC score	0.032845 (rank : 212)	θ value	5.27518 (rank : 186)
Query Neighborhood Hits	233	Target Neighborhood Hits	146	Shared Neighborhood Hits	11
SwissProt Accessions	Q7TSG2, Q7TSS7, Q9D4S8	Gene names	Ctdp1, Fcp1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

PKP4_HUMAN
NC score	0.032841 (rank : 213)	θ value	0.47712 (rank : 81)
Query Neighborhood Hits	233	Target Neighborhood Hits	107	Shared Neighborhood Hits	8
SwissProt Accessions	Q99569	Gene names	PKP4
Domain Architecture
Description	Plakophilin-4 (p0071).

BAI1_HUMAN
NC score	0.032668 (rank : 214)	θ value	0.0563607 (rank : 37)
Query Neighborhood Hits	233	Target Neighborhood Hits	375	Shared Neighborhood Hits	20
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

RBBP6_MOUSE
NC score	0.031504 (rank : 215)	θ value	8.99809 (rank : 227)
Query Neighborhood Hits	233	Target Neighborhood Hits	1014	Shared Neighborhood Hits	45
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

CDSN_MOUSE
NC score	0.030300 (rank : 216)	θ value	1.81305 (rank : 124)
Query Neighborhood Hits	233	Target Neighborhood Hits	131	Shared Neighborhood Hits	7
SwissProt Accessions	Q7TPC1	Gene names	Cdsn
Domain Architecture	No domain graphic available
Description	Corneodesmosin precursor.

LRP6_MOUSE
NC score	0.029914 (rank : 217)	θ value	0.21417 (rank : 58)
Query Neighborhood Hits	233	Target Neighborhood Hits	232	Shared Neighborhood Hits	9
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

MYCB2_HUMAN
NC score	0.029730 (rank : 218)	θ value	6.88961 (rank : 207)
Query Neighborhood Hits	233	Target Neighborhood Hits	390	Shared Neighborhood Hits	28
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

BAI1_MOUSE
NC score	0.029728 (rank : 219)	θ value	0.47712 (rank : 77)
Query Neighborhood Hits	233	Target Neighborhood Hits	340	Shared Neighborhood Hits	16
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

LRP6_HUMAN
NC score	0.029449 (rank : 220)	θ value	0.21417 (rank : 57)
Query Neighborhood Hits	233	Target Neighborhood Hits	235	Shared Neighborhood Hits	8
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

SOS1_HUMAN
NC score	0.028951 (rank : 221)	θ value	1.38821 (rank : 120)
Query Neighborhood Hits	233	Target Neighborhood Hits	274	Shared Neighborhood Hits	25
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

ARHG7_MOUSE
NC score	0.028835 (rank : 222)	θ value	0.365318 (rank : 67)
Query Neighborhood Hits	233	Target Neighborhood Hits	396	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

PTN23_HUMAN
NC score	0.028280 (rank : 223)	θ value	1.38821 (rank : 118)
Query Neighborhood Hits	233	Target Neighborhood Hits	646	Shared Neighborhood Hits	37
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

CD2AP_HUMAN
NC score	0.027883 (rank : 224)	θ value	2.36792 (rank : 137)
Query Neighborhood Hits	233	Target Neighborhood Hits	315	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

PDC6I_MOUSE
NC score	0.027804 (rank : 225)	θ value	6.88961 (rank : 209)
Query Neighborhood Hits	233	Target Neighborhood Hits	275	Shared Neighborhood Hits	23
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

BMX_HUMAN
NC score	0.027792 (rank : 226)	θ value	0.0252991 (rank : 31)
Query Neighborhood Hits	233	Target Neighborhood Hits	942	Shared Neighborhood Hits	35
SwissProt Accessions	P51813, O60564, Q12871	Gene names	BMX
Domain Architecture
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38).

CE025_HUMAN
NC score	0.027022 (rank : 227)	θ value	5.27518 (rank : 185)
Query Neighborhood Hits	233	Target Neighborhood Hits	114	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NDZ2, Q6NXN8, Q6ZTU4, Q8IZ15	Gene names	C5orf25
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C5orf25.

UN119_HUMAN
NC score	0.026957 (rank : 228)	θ value	2.36792 (rank : 152)
Query Neighborhood Hits	233	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q13432, O95126	Gene names	UNC119, RG4
Domain Architecture
Description	Unc-119 protein homolog (Retinal protein 4) (HRG4).

ANR41_HUMAN
NC score	0.026544 (rank : 229)	θ value	0.47712 (rank : 76)
Query Neighborhood Hits	233	Target Neighborhood Hits	332	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

BMX_MOUSE
NC score	0.026537 (rank : 230)	θ value	0.0431538 (rank : 35)
Query Neighborhood Hits	233	Target Neighborhood Hits	912	Shared Neighborhood Hits	34
SwissProt Accessions	P97504	Gene names	Bmx
Domain Architecture	No domain graphic available
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein homolog).

DAB2_MOUSE
NC score	0.026160 (rank : 231)	θ value	6.88961 (rank : 198)
Query Neighborhood Hits	233	Target Neighborhood Hits	163	Shared Neighborhood Hits	19
SwissProt Accessions	P98078, Q3U3K1, Q91W56, Q923E1	Gene names	Dab2, Doc2
Domain Architecture
Description	Disabled homolog 2 (DOC-2) (Mitogen-responsive phosphoprotein).

CSKI1_MOUSE
NC score	0.026116 (rank : 232)	θ value	1.81305 (rank : 125)
Query Neighborhood Hits	233	Target Neighborhood Hits	1031	Shared Neighborhood Hits	92
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

ZYX_MOUSE
NC score	0.025298 (rank : 233)	θ value	8.99809 (rank : 233)
Query Neighborhood Hits	233	Target Neighborhood Hits	347	Shared Neighborhood Hits	22
SwissProt Accessions	Q62523, P70461	Gene names	Zyx
Domain Architecture
Description	Zyxin.

CJ026_MOUSE
NC score	0.024733 (rank : 234)	θ value	8.99809 (rank : 217)
Query Neighborhood Hits	233	Target Neighborhood Hits	92	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BGW2, Q3TF48, Q3U3M2, Q6PD43, Q8R0W8	Gene names	D19Wsu162e
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C10orf26 homolog.

PKP4_MOUSE
NC score	0.024656 (rank : 235)	θ value	1.38821 (rank : 117)
Query Neighborhood Hits	233	Target Neighborhood Hits	129	Shared Neighborhood Hits	7
SwissProt Accessions	Q68FH0, Q640N0, Q68G56, Q8BK47, Q8BVH1, Q9CRE3	Gene names	Pkp4, Armrp
Domain Architecture	No domain graphic available
Description	Plakophilin-4 (Armadillo-related protein).

AF17_HUMAN
NC score	0.024533 (rank : 236)	θ value	4.03905 (rank : 165)
Query Neighborhood Hits	233	Target Neighborhood Hits	230	Shared Neighborhood Hits	18
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

NECD_HUMAN
NC score	0.023967 (rank : 237)	θ value	1.06291 (rank : 103)
Query Neighborhood Hits	233	Target Neighborhood Hits	82	Shared Neighborhood Hits	11
SwissProt Accessions	Q99608	Gene names	NDN
Domain Architecture
Description	Necdin.

ACK1_HUMAN
NC score	0.023109 (rank : 238)	θ value	0.163984 (rank : 52)
Query Neighborhood Hits	233	Target Neighborhood Hits	1140	Shared Neighborhood Hits	69
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

FBLI1_MOUSE
NC score	0.022586 (rank : 239)	θ value	0.813845 (rank : 96)
Query Neighborhood Hits	233	Target Neighborhood Hits	228	Shared Neighborhood Hits	13
SwissProt Accessions	Q71FD7, Q99J35	Gene names	Fblim1, Cal
Domain Architecture	No domain graphic available
Description	Filamin-binding LIM protein 1 (CSX-associated LIM).

SCAM3_HUMAN
NC score	0.022544 (rank : 240)	θ value	3.0926 (rank : 161)
Query Neighborhood Hits	233	Target Neighborhood Hits	29	Shared Neighborhood Hits	6
SwissProt Accessions	O14828, O15128, Q96FR8, Q9BPY0	Gene names	SCAMP3, PROPIN1
Domain Architecture
Description	Secretory carrier-associated membrane protein 3 (Secretory carrier membrane protein 3).

FGD1_HUMAN
NC score	0.022195 (rank : 241)	θ value	1.38821 (rank : 112)
Query Neighborhood Hits	233	Target Neighborhood Hits	367	Shared Neighborhood Hits	41
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

SPEG_MOUSE
NC score	0.021709 (rank : 242)	θ value	0.47712 (rank : 83)
Query Neighborhood Hits	233	Target Neighborhood Hits	1959	Shared Neighborhood Hits	92
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

ACK1_MOUSE
NC score	0.021651 (rank : 243)	θ value	0.21417 (rank : 55)
Query Neighborhood Hits	233	Target Neighborhood Hits	1080	Shared Neighborhood Hits	57
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

ABI3_HUMAN
NC score	0.021422 (rank : 244)	θ value	8.99809 (rank : 216)
Query Neighborhood Hits	233	Target Neighborhood Hits	227	Shared Neighborhood Hits	16
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

SF3A1_MOUSE
NC score	0.021257 (rank : 245)	θ value	8.99809 (rank : 228)
Query Neighborhood Hits	233	Target Neighborhood Hits	198	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K4Z5, Q8C0M7, Q8C128, Q8C175, Q921T3	Gene names	Sf3a1
Domain Architecture	No domain graphic available
Description	Splicing factor 3 subunit 1 (SF3a120).

ST5_HUMAN
NC score	0.019555 (rank : 246)	θ value	8.99809 (rank : 230)
Query Neighborhood Hits	233	Target Neighborhood Hits	151	Shared Neighborhood Hits	14
SwissProt Accessions	P78524, P78523, Q16492, Q7KYY2, Q7KZ12, Q8NE12, Q9BQQ6	Gene names	ST5, DENND2B, HTS1
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (HeLa tumor suppression 1) (DENN domain-containing protein 2B).

ST5_MOUSE
NC score	0.018243 (rank : 247)	θ value	2.36792 (rank : 151)
Query Neighborhood Hits	233	Target Neighborhood Hits	126	Shared Neighborhood Hits	10
SwissProt Accessions	Q924W7, Q78H54, Q8K2P3, Q924W8	Gene names	St5, Dennd2b
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (DENN domain-containing protein 2B).

NECD_MOUSE
NC score	0.017674 (rank : 248)	θ value	4.03905 (rank : 172)
Query Neighborhood Hits	233	Target Neighborhood Hits	85	Shared Neighborhood Hits	13
SwissProt Accessions	P25233, Q542W7, Q61951	Gene names	Ndn
Domain Architecture
Description	Necdin.

BNIP3_HUMAN
NC score	0.017062 (rank : 249)	θ value	5.27518 (rank : 181)
Query Neighborhood Hits	233	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q12983, O14620, Q96GP0	Gene names	BNIP3, NIP3
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3.

CARD9_HUMAN
NC score	0.016053 (rank : 250)	θ value	6.88961 (rank : 194)
Query Neighborhood Hits	233	Target Neighborhood Hits	602	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H257, Q5SXM6, Q9H854	Gene names	CARD9
Domain Architecture
Description	Caspase recruitment domain-containing protein 9 (hCARD9).

LTBP4_MOUSE
NC score	0.014623 (rank : 251)	θ value	0.365318 (rank : 72)
Query Neighborhood Hits	233	Target Neighborhood Hits	607	Shared Neighborhood Hits	26
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

HDAC9_MOUSE
NC score	0.013658 (rank : 252)	θ value	6.88961 (rank : 204)
Query Neighborhood Hits	233	Target Neighborhood Hits	186	Shared Neighborhood Hits	7
SwissProt Accessions	Q99N13, Q9EPT2	Gene names	Hdac9, Hdac7b, Hdrp, Mitr
Domain Architecture	No domain graphic available
Description	Histone deacetylase 9 (HD9) (HD7B) (Histone deacetylase-related protein) (MEF2-interacting transcription repressor MITR).

SAFB2_HUMAN
NC score	0.013494 (rank : 253)	θ value	4.03905 (rank : 174)
Query Neighborhood Hits	233	Target Neighborhood Hits	720	Shared Neighborhood Hits	20
SwissProt Accessions	Q14151, Q8TB13	Gene names	SAFB2, KIAA0138
Domain Architecture
Description	Scaffold attachment factor B2.

MEF2A_MOUSE
NC score	0.013379 (rank : 254)	θ value	3.0926 (rank : 157)
Query Neighborhood Hits	233	Target Neighborhood Hits	56	Shared Neighborhood Hits	5
SwissProt Accessions	Q60929	Gene names	Mef2a
Domain Architecture
Description	Myocyte-specific enhancer factor 2A.

P3C2B_HUMAN
NC score	0.011424 (rank : 255)	θ value	2.36792 (rank : 149)
Query Neighborhood Hits	233	Target Neighborhood Hits	148	Shared Neighborhood Hits	7
SwissProt Accessions	O00750, O95666, Q5SW99	Gene names	PIK3C2B
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-beta) (PtdIns-3-kinase C2 beta) (PI3K-C2beta) (C2-PI3K).

TITIN_HUMAN
NC score	0.011036 (rank : 256)	θ value	5.27518 (rank : 190)
Query Neighborhood Hits	233	Target Neighborhood Hits	2923	Shared Neighborhood Hits	76
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

SN1L2_MOUSE
NC score	0.010778 (rank : 257)	θ value	0.0736092 (rank : 43)
Query Neighborhood Hits	233	Target Neighborhood Hits	944	Shared Neighborhood Hits	20
SwissProt Accessions	Q8CFH6	Gene names	Snf1lk2, Sik2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SNF1-like kinase 2 (EC 2.7.11.1) (Salt-inducible kinase 2).

GPR64_MOUSE
NC score	0.010533 (rank : 258)	θ value	6.88961 (rank : 203)
Query Neighborhood Hits	233	Target Neighborhood Hits	156	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CJ12, Q8BL10, Q8CJ08, Q8CJ09, Q8CJ10	Gene names	Gpr64, Me6
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (Me6 receptor).

PCD15_HUMAN
NC score	0.009586 (rank : 259)	θ value	1.81305 (rank : 130)
Query Neighborhood Hits	233	Target Neighborhood Hits	289	Shared Neighborhood Hits	13
SwissProt Accessions	Q96QU1, Q96QT8	Gene names	PCDH15
Domain Architecture
Description	Protocadherin-15 precursor.

TTP_HUMAN
NC score	0.009541 (rank : 260)	θ value	8.99809 (rank : 232)
Query Neighborhood Hits	233	Target Neighborhood Hits	86	Shared Neighborhood Hits	5
SwissProt Accessions	P26651	Gene names	ZFP36, G0S24, TIS11A, TTP
Domain Architecture
Description	Tristetraproline (TTP) (Zinc finger protein 36 homolog) (Zfp-36) (TIS11A protein) (TIS11) (Growth factor-inducible nuclear protein NUP475) (G0/G1 switch regulatory protein 24).

HCN4_HUMAN
NC score	0.009496 (rank : 261)	θ value	8.99809 (rank : 219)
Query Neighborhood Hits	233	Target Neighborhood Hits	303	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

DTX2_MOUSE
NC score	0.009463 (rank : 262)	θ value	6.88961 (rank : 200)
Query Neighborhood Hits	233	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R3P2, Q9CZV3, Q9ER07, Q9ER08	Gene names	Dtx2
Domain Architecture
Description	Protein deltex-2 (Deltex-2) (Deltex2) (mDTX2).

ANR38_HUMAN
NC score	0.009455 (rank : 263)	θ value	5.27518 (rank : 180)
Query Neighborhood Hits	233	Target Neighborhood Hits	443	Shared Neighborhood Hits	19
SwissProt Accessions	Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3	Gene names	ANKRD38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

MPP8_HUMAN
NC score	0.009435 (rank : 264)	θ value	8.99809 (rank : 221)
Query Neighborhood Hits	233	Target Neighborhood Hits	948	Shared Neighborhood Hits	28
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

SORL_MOUSE
NC score	0.009399 (rank : 265)	θ value	8.99809 (rank : 229)
Query Neighborhood Hits	233	Target Neighborhood Hits	439	Shared Neighborhood Hits	9
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

EGR2_MOUSE
NC score	0.008777 (rank : 266)	θ value	0.0961366 (rank : 45)
Query Neighborhood Hits	233	Target Neighborhood Hits	745	Shared Neighborhood Hits	14
SwissProt Accessions	P08152	Gene names	Egr2, Egr-2, Krox-20, Zfp-25
Domain Architecture	No domain graphic available
Description	Early growth response protein 2 (EGR-2) (Krox-20 protein).

DDX20_MOUSE
NC score	0.008087 (rank : 267)	θ value	2.36792 (rank : 138)
Query Neighborhood Hits	233	Target Neighborhood Hits	177	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

FOXC1_MOUSE
NC score	0.007251 (rank : 268)	θ value	2.36792 (rank : 142)
Query Neighborhood Hits	233	Target Neighborhood Hits	218	Shared Neighborhood Hits	10
SwissProt Accessions	Q61572, O88409, Q61582	Gene names	Foxc1, Fkh1, Fkhl7, Freac3, Mf1
Domain Architecture
Description	Forkhead box protein C1 (Forkhead-related protein FKHL7) (Forkhead- related transcription factor 3) (FREAC-3) (Transcription factor FKH-1) (Mesoderm/mesenchyme forkhead 1) (MF-1).

CD2L7_HUMAN
NC score	0.007187 (rank : 269)	θ value	6.88961 (rank : 195)
Query Neighborhood Hits	233	Target Neighborhood Hits	1275	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

KLF10_MOUSE
NC score	0.007055 (rank : 270)	θ value	1.06291 (rank : 100)
Query Neighborhood Hits	233	Target Neighborhood Hits	741	Shared Neighborhood Hits	12
SwissProt Accessions	O89091	Gene names	Klf10, Gdnfif, Tieg, Tieg1
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 10 (Transforming growth factor-beta-inducible early growth response protein 1) (TGFB-inducible early growth response protein 1) (TIEG-1) (GDNF-inducible factor) (Transcription factor GIF) (mGIF).

KSR2_HUMAN
NC score	0.006595 (rank : 271)	θ value	8.99809 (rank : 220)
Query Neighborhood Hits	233	Target Neighborhood Hits	920	Shared Neighborhood Hits	22
SwissProt Accessions	Q6VAB6, Q8N775	Gene names	KSR2
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-2 (hKSR2).

BOC_MOUSE
NC score	0.006514 (rank : 272)	θ value	5.27518 (rank : 182)
Query Neighborhood Hits	233	Target Neighborhood Hits	433	Shared Neighborhood Hits	10
SwissProt Accessions	Q6AZB0, Q6KAM5, Q6P5H3, Q7TMJ3, Q8CE73, Q8CE91, Q8R377, Q923W7	Gene names	Boc
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

UBP51_HUMAN
NC score	0.006077 (rank : 273)	θ value	6.88961 (rank : 215)
Query Neighborhood Hits	233	Target Neighborhood Hits	162	Shared Neighborhood Hits	10
SwissProt Accessions	Q70EK9, Q8IWJ8	Gene names	USP51
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51).

KLF2_MOUSE
NC score	0.005822 (rank : 274)	θ value	1.06291 (rank : 101)
Query Neighborhood Hits	233	Target Neighborhood Hits	738	Shared Neighborhood Hits	8
SwissProt Accessions	Q60843	Gene names	Klf2, Lklf
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 2 (Lung krueppel-like factor).

FA8_MOUSE
NC score	0.005335 (rank : 275)	θ value	8.99809 (rank : 218)
Query Neighborhood Hits	233	Target Neighborhood Hits	100	Shared Neighborhood Hits	6
SwissProt Accessions	Q06194	Gene names	F8, Cf8, F8c
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component).

STB5L_MOUSE
NC score	0.004882 (rank : 276)	θ value	8.99809 (rank : 231)
Query Neighborhood Hits	233	Target Neighborhood Hits	138	Shared Neighborhood Hits	2
SwissProt Accessions	Q5DQR4, Q3TSM3, Q3UVG2, Q5DQR1, Q5DQR2, Q5DQR3, Q8BS52	Gene names	Stxbp5l, Llgl4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 5-like (Tomosyn-2) (Lethal(2) giant larvae protein homolog 4).

EGR2_HUMAN
NC score	0.002769 (rank : 277)	θ value	4.03905 (rank : 171)
Query Neighborhood Hits	233	Target Neighborhood Hits	728	Shared Neighborhood Hits	9
SwissProt Accessions	P11161, Q8IV26, Q9UNA6	Gene names	EGR2, KROX20
Domain Architecture	No domain graphic available
Description	Early growth response protein 2 (EGR-2) (Krox-20 protein) (AT591).

BCL6_MOUSE
NC score	-0.000698 (rank : 278)	θ value	4.03905 (rank : 166)
Query Neighborhood Hits	233	Target Neighborhood Hits	913	Shared Neighborhood Hits	26
SwissProt Accessions	P41183, Q61065	Gene names	Bcl6, Bcl-6
Domain Architecture
Description	B-cell lymphoma 6 protein homolog.