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Network neighborhood for query Sequence : 3BP2_HUMAN

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3BP2_HUMAN
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

3BP2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	296	Target Neighborhood Hits	296	Shared Neighborhood Hits	296
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

3BP2_MOUSE
θ value	0 (rank : 2)	NC score	0.925478 (rank : 2)
Query Neighborhood Hits	296	Target Neighborhood Hits	142	Shared Neighborhood Hits	90
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

PKHA6_MOUSE
θ value	2.21117e-06 (rank : 3)	NC score	0.343618 (rank : 3)
Query Neighborhood Hits	296	Target Neighborhood Hits	591	Shared Neighborhood Hits	89
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA6_HUMAN
θ value	2.88788e-06 (rank : 4)	NC score	0.338320 (rank : 4)
Query Neighborhood Hits	296	Target Neighborhood Hits	556	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

RHG25_MOUSE
θ value	0.00020696 (rank : 5)	NC score	0.211178 (rank : 24)
Query Neighborhood Hits	296	Target Neighborhood Hits	492	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

CYH3_HUMAN
θ value	0.00035302 (rank : 6)	NC score	0.271813 (rank : 12)
Query Neighborhood Hits	296	Target Neighborhood Hits	137	Shared Neighborhood Hits	45
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

PRGC2_HUMAN
θ value	0.00035302 (rank : 7)	NC score	0.135006 (rank : 33)
Query Neighborhood Hits	296	Target Neighborhood Hits	272	Shared Neighborhood Hits	41
SwissProt Accessions	Q86YN6, Q86YN3, Q86YN4, Q86YN5, Q8N1N9, Q8TDE4, Q8TDE5	Gene names	PPARGC1B, PERC, PGC1, PGC1B, PPARGC1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta) (PGC-1-related estrogen receptor alpha coactivator) (PPARGC-1-beta) (PGC-1-beta).

NFH_MOUSE
θ value	0.000461057 (rank : 8)	NC score	0.084768 (rank : 119)
Query Neighborhood Hits	296	Target Neighborhood Hits	2247	Shared Neighborhood Hits	151
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

CYH3_MOUSE
θ value	0.000602161 (rank : 9)	NC score	0.271236 (rank : 13)
Query Neighborhood Hits	296	Target Neighborhood Hits	148	Shared Neighborhood Hits	45
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

SAPS1_HUMAN
θ value	0.000602161 (rank : 10)	NC score	0.126188 (rank : 38)
Query Neighborhood Hits	296	Target Neighborhood Hits	704	Shared Neighborhood Hits	110
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

CYH1_HUMAN
θ value	0.000786445 (rank : 11)	NC score	0.269913 (rank : 15)
Query Neighborhood Hits	296	Target Neighborhood Hits	184	Shared Neighborhood Hits	48
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

CYH1_MOUSE
θ value	0.000786445 (rank : 12)	NC score	0.268628 (rank : 16)
Query Neighborhood Hits	296	Target Neighborhood Hits	176	Shared Neighborhood Hits	47
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

CYH4_MOUSE
θ value	0.000786445 (rank : 13)	NC score	0.268063 (rank : 18)
Query Neighborhood Hits	296	Target Neighborhood Hits	134	Shared Neighborhood Hits	45
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

PKHA4_HUMAN
θ value	0.000786445 (rank : 14)	NC score	0.311410 (rank : 5)
Query Neighborhood Hits	296	Target Neighborhood Hits	283	Shared Neighborhood Hits	69
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PKHA5_HUMAN
θ value	0.000786445 (rank : 15)	NC score	0.264823 (rank : 19)
Query Neighborhood Hits	296	Target Neighborhood Hits	455	Shared Neighborhood Hits	48
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

CYH4_HUMAN
θ value	0.00102713 (rank : 16)	NC score	0.268114 (rank : 17)
Query Neighborhood Hits	296	Target Neighborhood Hits	135	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UIA0, Q5R3F9, Q9UGT6	Gene names	PSCD4, CYT4
Domain Architecture
Description	Cytohesin-4.

RHG25_HUMAN
θ value	0.00102713 (rank : 17)	NC score	0.202035 (rank : 27)
Query Neighborhood Hits	296	Target Neighborhood Hits	550	Shared Neighborhood Hits	55
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

DAPP1_MOUSE
θ value	0.00228821 (rank : 18)	NC score	0.246640 (rank : 22)
Query Neighborhood Hits	296	Target Neighborhood Hits	225	Shared Neighborhood Hits	53
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

PKHA4_MOUSE
θ value	0.00228821 (rank : 19)	NC score	0.308497 (rank : 6)
Query Neighborhood Hits	296	Target Neighborhood Hits	202	Shared Neighborhood Hits	50
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

CYH2_HUMAN
θ value	0.00298849 (rank : 20)	NC score	0.263178 (rank : 20)
Query Neighborhood Hits	296	Target Neighborhood Hits	175	Shared Neighborhood Hits	45
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

CYH2_MOUSE
θ value	0.00298849 (rank : 21)	NC score	0.263076 (rank : 21)
Query Neighborhood Hits	296	Target Neighborhood Hits	171	Shared Neighborhood Hits	45
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

PLEK2_MOUSE
θ value	0.00298849 (rank : 22)	NC score	0.275981 (rank : 8)
Query Neighborhood Hits	296	Target Neighborhood Hits	96	Shared Neighborhood Hits	33
SwissProt Accessions	Q9WV52	Gene names	Plek2
Domain Architecture
Description	Pleckstrin-2.

DAPP1_HUMAN
θ value	0.00390308 (rank : 23)	NC score	0.245233 (rank : 23)
Query Neighborhood Hits	296	Target Neighborhood Hits	227	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

MUC1_HUMAN
θ value	0.00390308 (rank : 24)	NC score	0.131374 (rank : 34)
Query Neighborhood Hits	296	Target Neighborhood Hits	975	Shared Neighborhood Hits	136
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

MYO10_HUMAN
θ value	0.00390308 (rank : 25)	NC score	0.077779 (rank : 148)
Query Neighborhood Hits	296	Target Neighborhood Hits	920	Shared Neighborhood Hits	61
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

PKHA1_HUMAN
θ value	0.00390308 (rank : 26)	NC score	0.275178 (rank : 9)
Query Neighborhood Hits	296	Target Neighborhood Hits	127	Shared Neighborhood Hits	41
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA1_MOUSE
θ value	0.00390308 (rank : 27)	NC score	0.273804 (rank : 10)
Query Neighborhood Hits	296	Target Neighborhood Hits	120	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PLEK_HUMAN
θ value	0.00509761 (rank : 28)	NC score	0.286813 (rank : 7)
Query Neighborhood Hits	296	Target Neighborhood Hits	110	Shared Neighborhood Hits	43
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

PRRT3_HUMAN
θ value	0.00509761 (rank : 29)	NC score	0.175135 (rank : 28)
Query Neighborhood Hits	296	Target Neighborhood Hits	998	Shared Neighborhood Hits	156
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

PLEK2_HUMAN
θ value	0.00665767 (rank : 30)	NC score	0.270976 (rank : 14)
Query Neighborhood Hits	296	Target Neighborhood Hits	101	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

DIAP1_MOUSE
θ value	0.00869519 (rank : 31)	NC score	0.095717 (rank : 96)
Query Neighborhood Hits	296	Target Neighborhood Hits	839	Shared Neighborhood Hits	63
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

PDZD8_HUMAN
θ value	0.00869519 (rank : 32)	NC score	0.093056 (rank : 102)
Query Neighborhood Hits	296	Target Neighborhood Hits	185	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

SET1A_HUMAN
θ value	0.0113563 (rank : 33)	NC score	0.109331 (rank : 59)
Query Neighborhood Hits	296	Target Neighborhood Hits	690	Shared Neighborhood Hits	66
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

LCP2_HUMAN
θ value	0.0193708 (rank : 34)	NC score	0.145629 (rank : 31)
Query Neighborhood Hits	296	Target Neighborhood Hits	531	Shared Neighborhood Hits	108
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

CSK_MOUSE
θ value	0.0252991 (rank : 35)	NC score	0.045135 (rank : 344)
Query Neighborhood Hits	296	Target Neighborhood Hits	1009	Shared Neighborhood Hits	37
SwissProt Accessions	P41241, Q03143	Gene names	Csk
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase MPK-2) (p50CSK).

FA47B_HUMAN
θ value	0.0252991 (rank : 36)	NC score	0.153468 (rank : 30)
Query Neighborhood Hits	296	Target Neighborhood Hits	431	Shared Neighborhood Hits	105
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

PLEK_MOUSE
θ value	0.0252991 (rank : 37)	NC score	0.273434 (rank : 11)
Query Neighborhood Hits	296	Target Neighborhood Hits	109	Shared Neighborhood Hits	40
SwissProt Accessions	Q9JHK5, Q9ERI9	Gene names	Plek
Domain Architecture
Description	Pleckstrin.

RASA1_HUMAN
θ value	0.0252991 (rank : 38)	NC score	0.160291 (rank : 29)
Query Neighborhood Hits	296	Target Neighborhood Hits	258	Shared Neighborhood Hits	50
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

AFAD_HUMAN
θ value	0.0330416 (rank : 39)	NC score	0.055279 (rank : 277)
Query Neighborhood Hits	296	Target Neighborhood Hits	689	Shared Neighborhood Hits	34
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

MATK_HUMAN
θ value	0.0330416 (rank : 40)	NC score	0.043964 (rank : 349)
Query Neighborhood Hits	296	Target Neighborhood Hits	954	Shared Neighborhood Hits	36
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

MLL3_MOUSE
θ value	0.0330416 (rank : 41)	NC score	0.108769 (rank : 60)
Query Neighborhood Hits	296	Target Neighborhood Hits	1399	Shared Neighborhood Hits	137
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

EGR4_HUMAN
θ value	0.0431538 (rank : 42)	NC score	0.015877 (rank : 439)
Query Neighborhood Hits	296	Target Neighborhood Hits	939	Shared Neighborhood Hits	66
SwissProt Accessions	Q05215	Gene names	EGR4
Domain Architecture
Description	Early growth response protein 4 (EGR-4) (AT133).

MATK_MOUSE
θ value	0.0431538 (rank : 43)	NC score	0.043151 (rank : 351)
Query Neighborhood Hits	296	Target Neighborhood Hits	952	Shared Neighborhood Hits	36
SwissProt Accessions	P41242, Q6LE90	Gene names	Matk, Ctk, Ntk
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK).

CSK_HUMAN
θ value	0.0563607 (rank : 44)	NC score	0.044011 (rank : 348)
Query Neighborhood Hits	296	Target Neighborhood Hits	1009	Shared Neighborhood Hits	37
SwissProt Accessions	P41240, Q6FGZ6	Gene names	CSK
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase CYL).

FARP1_HUMAN
θ value	0.0563607 (rank : 45)	NC score	0.102037 (rank : 75)
Query Neighborhood Hits	296	Target Neighborhood Hits	241	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

H6ST3_HUMAN
θ value	0.0563607 (rank : 46)	NC score	0.057942 (rank : 256)
Query Neighborhood Hits	296	Target Neighborhood Hits	66	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IZP7, Q5W0L0, Q68CW6	Gene names	HS6ST3
Domain Architecture	No domain graphic available
Description	Heparan-sulfate 6-O-sulfotransferase 3 (EC 2.8.2.-) (HS6ST-3).

ACK1_MOUSE
θ value	0.0736092 (rank : 47)	NC score	0.041976 (rank : 356)
Query Neighborhood Hits	296	Target Neighborhood Hits	1080	Shared Neighborhood Hits	84
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

OST4_HUMAN
θ value	0.0736092 (rank : 48)	NC score	0.033953 (rank : 381)
Query Neighborhood Hits	296	Target Neighborhood Hits	95	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y661, Q5QI42, Q8NDC2	Gene names	HS3ST4, 3OST4
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 4 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4) (Heparan sulfate 3-O-sulfotransferase 4) (h3-OST-4).

APS_MOUSE
θ value	0.0961366 (rank : 49)	NC score	0.121268 (rank : 47)
Query Neighborhood Hits	296	Target Neighborhood Hits	134	Shared Neighborhood Hits	19
SwissProt Accessions	Q9JID9, O88936	Gene names	Aps
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

FMN2_MOUSE
θ value	0.0961366 (rank : 50)	NC score	0.127429 (rank : 35)
Query Neighborhood Hits	296	Target Neighborhood Hits	349	Shared Neighborhood Hits	68
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

MTR1L_HUMAN
θ value	0.0961366 (rank : 51)	NC score	0.013242 (rank : 445)
Query Neighborhood Hits	296	Target Neighborhood Hits	1180	Shared Neighborhood Hits	41
SwissProt Accessions	Q13585	Gene names	GPR50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).

FGD4_MOUSE
θ value	0.125558 (rank : 52)	NC score	0.082071 (rank : 130)
Query Neighborhood Hits	296	Target Neighborhood Hits	227	Shared Neighborhood Hits	31
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

HD_HUMAN
θ value	0.125558 (rank : 53)	NC score	0.054373 (rank : 288)
Query Neighborhood Hits	296	Target Neighborhood Hits	165	Shared Neighborhood Hits	22
SwissProt Accessions	P42858, Q9UQB7	Gene names	HD, IT15
Domain Architecture
Description	Huntingtin (Huntington disease protein) (HD protein).

RCOR2_HUMAN
θ value	0.125558 (rank : 54)	NC score	0.071093 (rank : 181)
Query Neighborhood Hits	296	Target Neighborhood Hits	114	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IZ40, Q96FP3	Gene names	RCOR2
Domain Architecture	No domain graphic available
Description	REST corepressor 2.

RCOR2_MOUSE
θ value	0.125558 (rank : 55)	NC score	0.071552 (rank : 176)
Query Neighborhood Hits	296	Target Neighborhood Hits	107	Shared Neighborhood Hits	24
SwissProt Accessions	Q8C796, Q9JMK4	Gene names	Rcor2
Domain Architecture	No domain graphic available
Description	REST corepressor 2 (M-CoREST).

TACC2_HUMAN
θ value	0.125558 (rank : 56)	NC score	0.053888 (rank : 291)
Query Neighborhood Hits	296	Target Neighborhood Hits	856	Shared Neighborhood Hits	58
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

UBP51_HUMAN
θ value	0.125558 (rank : 57)	NC score	0.028180 (rank : 401)
Query Neighborhood Hits	296	Target Neighborhood Hits	162	Shared Neighborhood Hits	17
SwissProt Accessions	Q70EK9, Q8IWJ8	Gene names	USP51
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51).

FGR_HUMAN
θ value	0.163984 (rank : 58)	NC score	0.039859 (rank : 364)
Query Neighborhood Hits	296	Target Neighborhood Hits	1067	Shared Neighborhood Hits	43
SwissProt Accessions	P09769, Q9UIQ3	Gene names	FGR, SRC2
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

FMN1A_MOUSE
θ value	0.163984 (rank : 59)	NC score	0.121570 (rank : 46)
Query Neighborhood Hits	296	Target Neighborhood Hits	423	Shared Neighborhood Hits	63
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

FMN1B_MOUSE
θ value	0.163984 (rank : 60)	NC score	0.123422 (rank : 44)
Query Neighborhood Hits	296	Target Neighborhood Hits	447	Shared Neighborhood Hits	67
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

NUP53_HUMAN
θ value	0.163984 (rank : 61)	NC score	0.083412 (rank : 122)
Query Neighborhood Hits	296	Target Neighborhood Hits	156	Shared Neighborhood Hits	41
SwissProt Accessions	Q8NFH5, Q4ZFZ9, Q53S95, Q8TDJ1	Gene names	NUP35, MP44, NUP53
Domain Architecture	No domain graphic available
Description	Nucleoporin NUP53 (Nuclear pore complex protein Nup53) (Nucleoporin Nup35) (35 kDa nucleoporin) (Mitotic phosphoprotein 44) (MP-44).

APS_HUMAN
θ value	0.21417 (rank : 62)	NC score	0.126419 (rank : 37)
Query Neighborhood Hits	296	Target Neighborhood Hits	162	Shared Neighborhood Hits	26
SwissProt Accessions	O14492	Gene names	APS
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

FARP2_MOUSE
θ value	0.21417 (rank : 63)	NC score	0.100647 (rank : 78)
Query Neighborhood Hits	296	Target Neighborhood Hits	209	Shared Neighborhood Hits	40
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

GNRP_HUMAN
θ value	0.21417 (rank : 64)	NC score	0.124888 (rank : 40)
Query Neighborhood Hits	296	Target Neighborhood Hits	239	Shared Neighborhood Hits	39
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

P55G_MOUSE
θ value	0.21417 (rank : 65)	NC score	0.097865 (rank : 91)
Query Neighborhood Hits	296	Target Neighborhood Hits	401	Shared Neighborhood Hits	25
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

YLPM1_MOUSE
θ value	0.21417 (rank : 66)	NC score	0.117314 (rank : 50)
Query Neighborhood Hits	296	Target Neighborhood Hits	505	Shared Neighborhood Hits	69
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

ZN206_HUMAN
θ value	0.21417 (rank : 67)	NC score	0.001407 (rank : 465)
Query Neighborhood Hits	296	Target Neighborhood Hits	853	Shared Neighborhood Hits	31
SwissProt Accessions	Q96SZ4	Gene names	ZNF206, ZSCAN10
Domain Architecture	No domain graphic available
Description	Zinc finger protein 206 (Zinc finger and SCAN domain-containing protein 10).

AB1IP_HUMAN
θ value	0.365318 (rank : 68)	NC score	0.088021 (rank : 112)
Query Neighborhood Hits	296	Target Neighborhood Hits	213	Shared Neighborhood Hits	51
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

ANTR1_MOUSE
θ value	0.365318 (rank : 69)	NC score	0.059528 (rank : 250)
Query Neighborhood Hits	296	Target Neighborhood Hits	143	Shared Neighborhood Hits	31
SwissProt Accessions	Q9CZ52	Gene names	Antxr1, Atr, Tem8
Domain Architecture
Description	Anthrax toxin receptor 1 precursor (Tumor endothelial marker 8).

BLK_HUMAN
θ value	0.365318 (rank : 70)	NC score	0.034381 (rank : 379)
Query Neighborhood Hits	296	Target Neighborhood Hits	994	Shared Neighborhood Hits	38
SwissProt Accessions	P51451, Q16291	Gene names	BLK
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

CD248_HUMAN
θ value	0.365318 (rank : 71)	NC score	0.055540 (rank : 275)
Query Neighborhood Hits	296	Target Neighborhood Hits	679	Shared Neighborhood Hits	84
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

P55G_HUMAN
θ value	0.365318 (rank : 72)	NC score	0.094432 (rank : 99)
Query Neighborhood Hits	296	Target Neighborhood Hits	451	Shared Neighborhood Hits	26
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

PRR12_HUMAN
θ value	0.365318 (rank : 73)	NC score	0.125237 (rank : 39)
Query Neighborhood Hits	296	Target Neighborhood Hits	460	Shared Neighborhood Hits	64
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

ZN750_MOUSE
θ value	0.365318 (rank : 74)	NC score	0.064561 (rank : 225)
Query Neighborhood Hits	296	Target Neighborhood Hits	346	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

FGD1_HUMAN
θ value	0.47712 (rank : 75)	NC score	0.092333 (rank : 105)
Query Neighborhood Hits	296	Target Neighborhood Hits	367	Shared Neighborhood Hits	56
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD1_MOUSE
θ value	0.47712 (rank : 76)	NC score	0.099221 (rank : 81)
Query Neighborhood Hits	296	Target Neighborhood Hits	387	Shared Neighborhood Hits	67
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

M3K9_HUMAN
θ value	0.47712 (rank : 77)	NC score	0.026016 (rank : 407)
Query Neighborhood Hits	296	Target Neighborhood Hits	1123	Shared Neighborhood Hits	41
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

RGS3_HUMAN
θ value	0.47712 (rank : 78)	NC score	0.091914 (rank : 106)
Query Neighborhood Hits	296	Target Neighborhood Hits	1375	Shared Neighborhood Hits	159
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

WBP11_HUMAN
θ value	0.47712 (rank : 79)	NC score	0.106616 (rank : 64)
Query Neighborhood Hits	296	Target Neighborhood Hits	354	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

WBP11_MOUSE
θ value	0.47712 (rank : 80)	NC score	0.106072 (rank : 68)
Query Neighborhood Hits	296	Target Neighborhood Hits	362	Shared Neighborhood Hits	50
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

BLNK_HUMAN
θ value	0.62314 (rank : 81)	NC score	0.126467 (rank : 36)
Query Neighborhood Hits	296	Target Neighborhood Hits	228	Shared Neighborhood Hits	54
SwissProt Accessions	Q8WV28, O75498, O75499	Gene names	BLNK, BASH, SLP65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (SLP-65).

CEND2_HUMAN
θ value	0.62314 (rank : 82)	NC score	0.098682 (rank : 89)
Query Neighborhood Hits	296	Target Neighborhood Hits	166	Shared Neighborhood Hits	45
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

PRCC_HUMAN
θ value	0.62314 (rank : 83)	NC score	0.079034 (rank : 143)
Query Neighborhood Hits	296	Target Neighborhood Hits	109	Shared Neighborhood Hits	25
SwissProt Accessions	Q92733, O00665, O00724	Gene names	PRCC, TPRC
Domain Architecture	No domain graphic available
Description	Proline-rich protein PRCC (Papillary renal cell carcinoma translocation-associated gene protein).

RIPK3_MOUSE
θ value	0.62314 (rank : 84)	NC score	0.025694 (rank : 409)
Query Neighborhood Hits	296	Target Neighborhood Hits	867	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QZL0	Gene names	Ripk3, Rip3
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (mRIP3).

WASP_MOUSE
θ value	0.62314 (rank : 85)	NC score	0.074371 (rank : 163)
Query Neighborhood Hits	296	Target Neighborhood Hits	223	Shared Neighborhood Hits	44
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

ACRO_HUMAN
θ value	0.813845 (rank : 86)	NC score	0.008935 (rank : 454)
Query Neighborhood Hits	296	Target Neighborhood Hits	291	Shared Neighborhood Hits	27
SwissProt Accessions	P10323, Q6ICK2	Gene names	ACR, ACRS
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

CBP_MOUSE
θ value	0.813845 (rank : 87)	NC score	0.081512 (rank : 135)
Query Neighborhood Hits	296	Target Neighborhood Hits	1051	Shared Neighborhood Hits	125
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

DRD4_HUMAN
θ value	0.813845 (rank : 88)	NC score	0.008926 (rank : 455)
Query Neighborhood Hits	296	Target Neighborhood Hits	886	Shared Neighborhood Hits	17
SwissProt Accessions	P21917	Gene names	DRD4
Domain Architecture
Description	D(4) dopamine receptor (Dopamine D4 receptor) (D(2C) dopamine receptor).

ESX1L_HUMAN
θ value	0.813845 (rank : 89)	NC score	0.023569 (rank : 415)
Query Neighborhood Hits	296	Target Neighborhood Hits	498	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N693, Q7Z6K7	Gene names	ESX1L, ESX1R
Domain Architecture
Description	Extraembryonic, spermatogenesis, homeobox 1-like protein.

ETV3_HUMAN
θ value	0.813845 (rank : 90)	NC score	0.045538 (rank : 342)
Query Neighborhood Hits	296	Target Neighborhood Hits	312	Shared Neighborhood Hits	46
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

FARP2_HUMAN
θ value	0.813845 (rank : 91)	NC score	0.092885 (rank : 103)
Query Neighborhood Hits	296	Target Neighborhood Hits	240	Shared Neighborhood Hits	43
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

LTBP4_MOUSE
θ value	0.813845 (rank : 92)	NC score	0.019202 (rank : 428)
Query Neighborhood Hits	296	Target Neighborhood Hits	607	Shared Neighborhood Hits	33
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

MLL4_HUMAN
θ value	0.813845 (rank : 93)	NC score	0.098929 (rank : 84)
Query Neighborhood Hits	296	Target Neighborhood Hits	722	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

PKN3_MOUSE
θ value	0.813845 (rank : 94)	NC score	0.014191 (rank : 443)
Query Neighborhood Hits	296	Target Neighborhood Hits	1009	Shared Neighborhood Hits	45
SwissProt Accessions	Q8K045	Gene names	Pkn3, Pknbeta
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

PLXB1_HUMAN
θ value	0.813845 (rank : 95)	NC score	0.032418 (rank : 387)
Query Neighborhood Hits	296	Target Neighborhood Hits	360	Shared Neighborhood Hits	53
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

PTN23_MOUSE
θ value	0.813845 (rank : 96)	NC score	0.041936 (rank : 357)
Query Neighborhood Hits	296	Target Neighborhood Hits	726	Shared Neighborhood Hits	66
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

RFX1_HUMAN
θ value	0.813845 (rank : 97)	NC score	0.051995 (rank : 314)
Query Neighborhood Hits	296	Target Neighborhood Hits	256	Shared Neighborhood Hits	38
SwissProt Accessions	P22670	Gene names	RFX1
Domain Architecture
Description	MHC class II regulatory factor RFX1 (RFX) (Enhancer factor C) (EF-C).

SFR15_HUMAN
θ value	0.813845 (rank : 98)	NC score	0.083013 (rank : 125)
Query Neighborhood Hits	296	Target Neighborhood Hits	368	Shared Neighborhood Hits	52
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

SON_HUMAN
θ value	0.813845 (rank : 99)	NC score	0.120659 (rank : 48)
Query Neighborhood Hits	296	Target Neighborhood Hits	1568	Shared Neighborhood Hits	181
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

TB182_HUMAN
θ value	0.813845 (rank : 100)	NC score	0.071493 (rank : 177)
Query Neighborhood Hits	296	Target Neighborhood Hits	414	Shared Neighborhood Hits	39
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

TITIN_HUMAN
θ value	0.813845 (rank : 101)	NC score	0.024440 (rank : 412)
Query Neighborhood Hits	296	Target Neighborhood Hits	2923	Shared Neighborhood Hits	116
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

3BP1_HUMAN
θ value	1.06291 (rank : 102)	NC score	0.074242 (rank : 164)
Query Neighborhood Hits	296	Target Neighborhood Hits	376	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

BLNK_MOUSE
θ value	1.06291 (rank : 103)	NC score	0.118778 (rank : 49)
Query Neighborhood Hits	296	Target Neighborhood Hits	296	Shared Neighborhood Hits	67
SwissProt Accessions	Q9QUN3, O88504	Gene names	Blnk, Bash, Ly57, Slp65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65) (Lymphocyte antigen 57).

CE025_HUMAN
θ value	1.06291 (rank : 104)	NC score	0.066201 (rank : 205)
Query Neighborhood Hits	296	Target Neighborhood Hits	114	Shared Neighborhood Hits	21
SwissProt Accessions	Q8NDZ2, Q6NXN8, Q6ZTU4, Q8IZ15	Gene names	C5orf25
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C5orf25.

CENG3_MOUSE
θ value	1.06291 (rank : 105)	NC score	0.048639 (rank : 340)
Query Neighborhood Hits	296	Target Neighborhood Hits	467	Shared Neighborhood Hits	19
SwissProt Accessions	Q8VHH5, Q812F7	Gene names	Centg3, Agap3
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CO3A1_HUMAN
θ value	1.06291 (rank : 106)	NC score	0.042416 (rank : 355)
Query Neighborhood Hits	296	Target Neighborhood Hits	452	Shared Neighborhood Hits	37
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

MLL3_HUMAN
θ value	1.06291 (rank : 107)	NC score	0.123638 (rank : 43)
Query Neighborhood Hits	296	Target Neighborhood Hits	1644	Shared Neighborhood Hits	161
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

P85A_HUMAN
θ value	1.06291 (rank : 108)	NC score	0.098933 (rank : 83)
Query Neighborhood Hits	296	Target Neighborhood Hits	479	Shared Neighborhood Hits	36
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

TACC2_MOUSE
θ value	1.06291 (rank : 109)	NC score	0.054752 (rank : 283)
Query Neighborhood Hits	296	Target Neighborhood Hits	774	Shared Neighborhood Hits	49
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

WASF2_MOUSE
θ value	1.06291 (rank : 110)	NC score	0.081688 (rank : 133)
Query Neighborhood Hits	296	Target Neighborhood Hits	315	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

ZN687_HUMAN
θ value	1.06291 (rank : 111)	NC score	0.031380 (rank : 389)
Query Neighborhood Hits	296	Target Neighborhood Hits	1244	Shared Neighborhood Hits	111
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

AMBN_HUMAN
θ value	1.38821 (rank : 112)	NC score	0.055571 (rank : 274)
Query Neighborhood Hits	296	Target Neighborhood Hits	107	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NP70, Q9H2X1, Q9H4L1	Gene names	AMBN
Domain Architecture
Description	Ameloblastin precursor.

ANTR1_HUMAN
θ value	1.38821 (rank : 113)	NC score	0.057488 (rank : 259)
Query Neighborhood Hits	296	Target Neighborhood Hits	128	Shared Neighborhood Hits	28
SwissProt Accessions	Q9H6X2, Q96P02, Q9NVP3	Gene names	ANTXR1, ATR, TEM8
Domain Architecture
Description	Anthrax toxin receptor 1 precursor (Tumor endothelial marker 8).

BMX_HUMAN
θ value	1.38821 (rank : 114)	NC score	0.039414 (rank : 365)
Query Neighborhood Hits	296	Target Neighborhood Hits	942	Shared Neighborhood Hits	57
SwissProt Accessions	P51813, O60564, Q12871	Gene names	BMX
Domain Architecture
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38).

CA106_MOUSE
θ value	1.38821 (rank : 115)	NC score	0.040943 (rank : 360)
Query Neighborhood Hits	296	Target Neighborhood Hits	89	Shared Neighborhood Hits	14
SwissProt Accessions	Q7TN12, Q7TN27, Q8BGK3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106 homolog.

CS007_MOUSE
θ value	1.38821 (rank : 116)	NC score	0.089123 (rank : 111)
Query Neighborhood Hits	296	Target Neighborhood Hits	464	Shared Neighborhood Hits	60
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

DAZP1_HUMAN
θ value	1.38821 (rank : 117)	NC score	0.029194 (rank : 399)
Query Neighborhood Hits	296	Target Neighborhood Hits	313	Shared Neighborhood Hits	30
SwissProt Accessions	Q96EP5, Q96MJ3, Q9NRR9	Gene names	DAZAP1
Domain Architecture
Description	DAZ-associated protein 1 (Deleted in azoospermia-associated protein 1).

DAZP1_MOUSE
θ value	1.38821 (rank : 118)	NC score	0.029498 (rank : 397)
Query Neighborhood Hits	296	Target Neighborhood Hits	313	Shared Neighborhood Hits	32
SwissProt Accessions	Q9JII5	Gene names	Dazap1
Domain Architecture
Description	DAZ-associated protein 1 (Deleted in azoospermia-associated protein 1).

FGD4_HUMAN
θ value	1.38821 (rank : 119)	NC score	0.073586 (rank : 166)
Query Neighborhood Hits	296	Target Neighborhood Hits	219	Shared Neighborhood Hits	30
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

GNRP_MOUSE
θ value	1.38821 (rank : 120)	NC score	0.116515 (rank : 51)
Query Neighborhood Hits	296	Target Neighborhood Hits	191	Shared Neighborhood Hits	44
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

HXB4_HUMAN
θ value	1.38821 (rank : 121)	NC score	0.011887 (rank : 448)
Query Neighborhood Hits	296	Target Neighborhood Hits	376	Shared Neighborhood Hits	22
SwissProt Accessions	P17483, Q9NTA0	Gene names	HOXB4, HOX2F
Domain Architecture
Description	Homeobox protein Hox-B4 (Hox-2F) (Hox-2.6).

JIP1_HUMAN
θ value	1.38821 (rank : 122)	NC score	0.059661 (rank : 249)
Query Neighborhood Hits	296	Target Neighborhood Hits	271	Shared Neighborhood Hits	48
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

JIP1_MOUSE
θ value	1.38821 (rank : 123)	NC score	0.060348 (rank : 246)
Query Neighborhood Hits	296	Target Neighborhood Hits	259	Shared Neighborhood Hits	50
SwissProt Accessions	Q9WVI9, O35145, Q925J8, Q9R1H9, Q9R1Z1, Q9WVI7, Q9WVI8	Gene names	Mapk8ip1, Ib1, Jip1, Mapk8ip, Prkm8ip
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain-1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

MAST4_HUMAN
θ value	1.38821 (rank : 124)	NC score	0.027918 (rank : 404)
Query Neighborhood Hits	296	Target Neighborhood Hits	1804	Shared Neighborhood Hits	116
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

MLL2_HUMAN
θ value	1.38821 (rank : 125)	NC score	0.101014 (rank : 77)
Query Neighborhood Hits	296	Target Neighborhood Hits	1788	Shared Neighborhood Hits	136
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

NCOA6_HUMAN
θ value	1.38821 (rank : 126)	NC score	0.121677 (rank : 45)
Query Neighborhood Hits	296	Target Neighborhood Hits	1202	Shared Neighborhood Hits	146
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NCOA6_MOUSE
θ value	1.38821 (rank : 127)	NC score	0.099807 (rank : 79)
Query Neighborhood Hits	296	Target Neighborhood Hits	1076	Shared Neighborhood Hits	122
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

P85A_MOUSE
θ value	1.38821 (rank : 128)	NC score	0.096423 (rank : 93)
Query Neighborhood Hits	296	Target Neighborhood Hits	435	Shared Neighborhood Hits	36
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

PCLO_HUMAN
θ value	1.38821 (rank : 129)	NC score	0.090854 (rank : 107)
Query Neighborhood Hits	296	Target Neighborhood Hits	2046	Shared Neighborhood Hits	150
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

RERE_MOUSE
θ value	1.38821 (rank : 130)	NC score	0.094390 (rank : 101)
Query Neighborhood Hits	296	Target Neighborhood Hits	785	Shared Neighborhood Hits	85
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

S23IP_MOUSE
θ value	1.38821 (rank : 131)	NC score	0.065533 (rank : 212)
Query Neighborhood Hits	296	Target Neighborhood Hits	363	Shared Neighborhood Hits	59
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

SSBP4_HUMAN
θ value	1.38821 (rank : 132)	NC score	0.084388 (rank : 120)
Query Neighborhood Hits	296	Target Neighborhood Hits	753	Shared Neighborhood Hits	125
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

TBC10_MOUSE
θ value	1.38821 (rank : 133)	NC score	0.025726 (rank : 408)
Query Neighborhood Hits	296	Target Neighborhood Hits	94	Shared Neighborhood Hits	12
SwissProt Accessions	P58802	Gene names	Tbc1d10a, Epi64, Tbc1d10
Domain Architecture
Description	TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa) (EPI64 protein).

VAV2_MOUSE
θ value	1.38821 (rank : 134)	NC score	0.065440 (rank : 214)
Query Neighborhood Hits	296	Target Neighborhood Hits	456	Shared Neighborhood Hits	43
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

ACK1_HUMAN
θ value	1.81305 (rank : 135)	NC score	0.040289 (rank : 362)
Query Neighborhood Hits	296	Target Neighborhood Hits	1140	Shared Neighborhood Hits	97
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

B4GN4_HUMAN
θ value	1.81305 (rank : 136)	NC score	0.045224 (rank : 343)
Query Neighborhood Hits	296	Target Neighborhood Hits	131	Shared Neighborhood Hits	17
SwissProt Accessions	Q76KP1, Q96LV2	Gene names	B4GALNT4
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 1 (EC 2.4.1.244) (NGalNAc-T1) (Beta- 1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4).

BAT2_HUMAN
θ value	1.81305 (rank : 137)	NC score	0.109460 (rank : 58)
Query Neighborhood Hits	296	Target Neighborhood Hits	931	Shared Neighborhood Hits	117
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CCD21_MOUSE
θ value	1.81305 (rank : 138)	NC score	0.022322 (rank : 417)
Query Neighborhood Hits	296	Target Neighborhood Hits	1135	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CENG2_HUMAN
θ value	1.81305 (rank : 139)	NC score	0.042522 (rank : 354)
Query Neighborhood Hits	296	Target Neighborhood Hits	471	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UPQ3, Q541S5, Q6P9D7, Q9NV93	Gene names	CENTG2, AGAP1, KIAA1099
Domain Architecture
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1).

CRTC1_HUMAN
θ value	1.81305 (rank : 140)	NC score	0.072489 (rank : 171)
Query Neighborhood Hits	296	Target Neighborhood Hits	319	Shared Neighborhood Hits	66
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

FHOD1_MOUSE
θ value	1.81305 (rank : 141)	NC score	0.078333 (rank : 144)
Query Neighborhood Hits	296	Target Neighborhood Hits	217	Shared Neighborhood Hits	43
SwissProt Accessions	Q6P9Q4, Q8BMK2	Gene names	Fhod1, Fhos1
Domain Architecture	No domain graphic available
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

FMN2_HUMAN
θ value	1.81305 (rank : 142)	NC score	0.124556 (rank : 41)
Query Neighborhood Hits	296	Target Neighborhood Hits	484	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

GGN_MOUSE
θ value	1.81305 (rank : 143)	NC score	0.098864 (rank : 86)
Query Neighborhood Hits	296	Target Neighborhood Hits	311	Shared Neighborhood Hits	58
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

K1802_MOUSE
θ value	1.81305 (rank : 144)	NC score	0.090131 (rank : 108)
Query Neighborhood Hits	296	Target Neighborhood Hits	1596	Shared Neighborhood Hits	163
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MICA1_HUMAN
θ value	1.81305 (rank : 145)	NC score	0.019003 (rank : 429)
Query Neighborhood Hits	296	Target Neighborhood Hits	279	Shared Neighborhood Hits	26
SwissProt Accessions	Q8TDZ2, Q7Z633, Q8IVS9, Q96G47, Q9H6X6, Q9H7I0, Q9HAA1, Q9UFF7	Gene names	MICAL1, MICAL, NICAL
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

MYO15_HUMAN
θ value	1.81305 (rank : 146)	NC score	0.043386 (rank : 350)
Query Neighborhood Hits	296	Target Neighborhood Hits	671	Shared Neighborhood Hits	119
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

NCOR2_HUMAN
θ value	1.81305 (rank : 147)	NC score	0.075388 (rank : 162)
Query Neighborhood Hits	296	Target Neighborhood Hits	870	Shared Neighborhood Hits	86
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

PKHA2_HUMAN
θ value	1.81305 (rank : 148)	NC score	0.205163 (rank : 26)
Query Neighborhood Hits	296	Target Neighborhood Hits	119	Shared Neighborhood Hits	42
SwissProt Accessions	Q9HB19	Gene names	PLEKHA2, TAPP2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2).

RSMN_HUMAN
θ value	1.81305 (rank : 149)	NC score	0.064920 (rank : 221)
Query Neighborhood Hits	296	Target Neighborhood Hits	110	Shared Neighborhood Hits	19
SwissProt Accessions	P63162, P14648, P17135	Gene names	SNRPN, HCERN3, SMN
Domain Architecture	No domain graphic available
Description	Small nuclear ribonucleoprotein-associated protein N (snRNP-N) (Sm protein N) (Sm-N) (SmN) (Sm-D) (Tissue-specific-splicing protein).

RSMN_MOUSE
θ value	1.81305 (rank : 150)	NC score	0.064920 (rank : 222)
Query Neighborhood Hits	296	Target Neighborhood Hits	110	Shared Neighborhood Hits	19
SwissProt Accessions	P63163, P14648, P17135	Gene names	Snrpn, Smn
Domain Architecture	No domain graphic available
Description	Small nuclear ribonucleoprotein-associated protein N (snRNP-N) (Sm protein N) (Sm-N) (SmN) (Sm-D) (Tissue-specific-splicing protein).

WASL_MOUSE
θ value	1.81305 (rank : 151)	NC score	0.094426 (rank : 100)
Query Neighborhood Hits	296	Target Neighborhood Hits	339	Shared Neighborhood Hits	62
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

ASPP1_HUMAN
θ value	2.36792 (rank : 152)	NC score	0.030890 (rank : 392)
Query Neighborhood Hits	296	Target Neighborhood Hits	956	Shared Neighborhood Hits	55
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

CEND3_HUMAN
θ value	2.36792 (rank : 153)	NC score	0.080452 (rank : 138)
Query Neighborhood Hits	296	Target Neighborhood Hits	275	Shared Neighborhood Hits	56
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

CENG1_HUMAN
θ value	2.36792 (rank : 154)	NC score	0.049669 (rank : 339)
Query Neighborhood Hits	296	Target Neighborhood Hits	544	Shared Neighborhood Hits	30
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

CENG1_MOUSE
θ value	2.36792 (rank : 155)	NC score	0.055197 (rank : 280)
Query Neighborhood Hits	296	Target Neighborhood Hits	531	Shared Neighborhood Hits	39
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

CJ108_HUMAN
θ value	2.36792 (rank : 156)	NC score	0.080271 (rank : 141)
Query Neighborhood Hits	296	Target Neighborhood Hits	165	Shared Neighborhood Hits	48
SwissProt Accessions	Q8N8Z3	Gene names	C10orf108
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C10orf108.

CS007_HUMAN
θ value	2.36792 (rank : 157)	NC score	0.062730 (rank : 232)
Query Neighborhood Hits	296	Target Neighborhood Hits	401	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

DHX37_HUMAN
θ value	2.36792 (rank : 158)	NC score	0.017314 (rank : 434)
Query Neighborhood Hits	296	Target Neighborhood Hits	133	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IY37, Q9BUI7, Q9P211	Gene names	DHX37, DDX37, KIAA1517
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX37 (EC 3.6.1.-) (DEAH box protein 37).

H6ST3_MOUSE
θ value	2.36792 (rank : 159)	NC score	0.043029 (rank : 352)
Query Neighborhood Hits	296	Target Neighborhood Hits	46	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QYK4	Gene names	Hs6st3
Domain Architecture	No domain graphic available
Description	Heparan-sulfate 6-O-sulfotransferase 3 (EC 2.8.2.-) (HS6ST-3) (mHS6ST- 3).

NFH_HUMAN
θ value	2.36792 (rank : 160)	NC score	0.037790 (rank : 367)
Query Neighborhood Hits	296	Target Neighborhood Hits	1242	Shared Neighborhood Hits	52
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PCD15_HUMAN
θ value	2.36792 (rank : 161)	NC score	0.013401 (rank : 444)
Query Neighborhood Hits	296	Target Neighborhood Hits	289	Shared Neighborhood Hits	28
SwissProt Accessions	Q96QU1, Q96QT8	Gene names	PCDH15
Domain Architecture
Description	Protocadherin-15 precursor.

PRG4_HUMAN
θ value	2.36792 (rank : 162)	NC score	0.082690 (rank : 126)
Query Neighborhood Hits	296	Target Neighborhood Hits	764	Shared Neighborhood Hits	70
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

RERE_HUMAN
θ value	2.36792 (rank : 163)	NC score	0.089141 (rank : 110)
Query Neighborhood Hits	296	Target Neighborhood Hits	779	Shared Neighborhood Hits	81
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

SETBP_HUMAN
θ value	2.36792 (rank : 164)	NC score	0.051278 (rank : 325)
Query Neighborhood Hits	296	Target Neighborhood Hits	305	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y6X0, Q9UEF3	Gene names	SETBP1, KIAA0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

SRRM1_HUMAN
θ value	2.36792 (rank : 165)	NC score	0.095837 (rank : 94)
Query Neighborhood Hits	296	Target Neighborhood Hits	690	Shared Neighborhood Hits	71
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

ZO2_MOUSE
θ value	2.36792 (rank : 166)	NC score	0.018013 (rank : 433)
Query Neighborhood Hits	296	Target Neighborhood Hits	296	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

BAT2_MOUSE
θ value	3.0926 (rank : 167)	NC score	0.097896 (rank : 90)
Query Neighborhood Hits	296	Target Neighborhood Hits	947	Shared Neighborhood Hits	121
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CCD96_MOUSE
θ value	3.0926 (rank : 168)	NC score	0.028308 (rank : 400)
Query Neighborhood Hits	296	Target Neighborhood Hits	704	Shared Neighborhood Hits	31
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CD2L7_HUMAN
θ value	3.0926 (rank : 169)	NC score	0.018560 (rank : 430)
Query Neighborhood Hits	296	Target Neighborhood Hits	1275	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

CENA2_HUMAN
θ value	3.0926 (rank : 170)	NC score	0.076890 (rank : 155)
Query Neighborhood Hits	296	Target Neighborhood Hits	83	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

CEND3_MOUSE
θ value	3.0926 (rank : 171)	NC score	0.076596 (rank : 157)
Query Neighborhood Hits	296	Target Neighborhood Hits	228	Shared Neighborhood Hits	50
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

CENG3_HUMAN
θ value	3.0926 (rank : 172)	NC score	0.044660 (rank : 346)
Query Neighborhood Hits	296	Target Neighborhood Hits	455	Shared Neighborhood Hits	18
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CTHR1_HUMAN
θ value	3.0926 (rank : 173)	NC score	0.028164 (rank : 402)
Query Neighborhood Hits	296	Target Neighborhood Hits	126	Shared Neighborhood Hits	5
SwissProt Accessions	Q96CG8, Q6UW91, Q8IX63	Gene names	CTHRC1
Domain Architecture	No domain graphic available
Description	Collagen triple helix repeat-containing protein 1 precursor (NMTC1 protein).

CTHR1_MOUSE
θ value	3.0926 (rank : 174)	NC score	0.028134 (rank : 403)
Query Neighborhood Hits	296	Target Neighborhood Hits	123	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D1D6	Gene names	Cthrc1
Domain Architecture	No domain graphic available
Description	Collagen triple helix repeat-containing protein 1 precursor.

DAAM1_HUMAN
θ value	3.0926 (rank : 175)	NC score	0.068302 (rank : 196)
Query Neighborhood Hits	296	Target Neighborhood Hits	483	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y4D1, Q86U34, Q8N1Z8, Q8TB39	Gene names	DAAM1, KIAA0666
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

DAAM2_MOUSE
θ value	3.0926 (rank : 176)	NC score	0.060903 (rank : 240)
Query Neighborhood Hits	296	Target Neighborhood Hits	371	Shared Neighborhood Hits	29
SwissProt Accessions	Q80U19, Q810J5	Gene names	Daam2, Kiaa0381
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 2.

ENL_HUMAN
θ value	3.0926 (rank : 177)	NC score	0.051367 (rank : 322)
Query Neighborhood Hits	296	Target Neighborhood Hits	305	Shared Neighborhood Hits	31
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

MYST3_HUMAN
θ value	3.0926 (rank : 178)	NC score	0.039286 (rank : 366)
Query Neighborhood Hits	296	Target Neighborhood Hits	772	Shared Neighborhood Hits	47
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

PCLO_MOUSE
θ value	3.0926 (rank : 179)	NC score	0.089677 (rank : 109)
Query Neighborhood Hits	296	Target Neighborhood Hits	2275	Shared Neighborhood Hits	174
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PKHA2_MOUSE
θ value	3.0926 (rank : 180)	NC score	0.207291 (rank : 25)
Query Neighborhood Hits	296	Target Neighborhood Hits	116	Shared Neighborhood Hits	39
SwissProt Accessions	Q9ERS5, Q8BY29	Gene names	Plekha2, Tapp2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2) (PH domain-containing adaptor PHAD47).

RAPH1_HUMAN
θ value	3.0926 (rank : 181)	NC score	0.098712 (rank : 88)
Query Neighborhood Hits	296	Target Neighborhood Hits	593	Shared Neighborhood Hits	92
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

RSMB_HUMAN
θ value	3.0926 (rank : 182)	NC score	0.058660 (rank : 254)
Query Neighborhood Hits	296	Target Neighborhood Hits	117	Shared Neighborhood Hits	18
SwissProt Accessions	P14678, Q15490, Q9UIS5	Gene names	SNRPB, COD, SNRPB1
Domain Architecture
Description	Small nuclear ribonucleoprotein-associated proteins B and B' (snRNP-B) (Sm protein B/B') (Sm-B/Sm-B') (SmB/SmB').

S23IP_HUMAN
θ value	3.0926 (rank : 183)	NC score	0.042950 (rank : 353)
Query Neighborhood Hits	296	Target Neighborhood Hits	134	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y6Y8, Q8IXH5, Q9BUK5	Gene names	SEC23IP
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein (p125).

SLAP2_MOUSE
θ value	3.0926 (rank : 184)	NC score	0.067162 (rank : 201)
Query Neighborhood Hits	296	Target Neighborhood Hits	136	Shared Neighborhood Hits	23
SwissProt Accessions	Q8R4L0, Q3UU74, Q8C0K2, Q8VI42, Q9D1Z9	Gene names	Sla2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2).

SPEG_MOUSE
θ value	3.0926 (rank : 185)	NC score	0.031247 (rank : 391)
Query Neighborhood Hits	296	Target Neighborhood Hits	1959	Shared Neighborhood Hits	131
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SREC2_HUMAN
θ value	3.0926 (rank : 186)	NC score	0.022003 (rank : 419)
Query Neighborhood Hits	296	Target Neighborhood Hits	645	Shared Neighborhood Hits	37
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

STRC_MOUSE
θ value	3.0926 (rank : 187)	NC score	0.029232 (rank : 398)
Query Neighborhood Hits	296	Target Neighborhood Hits	89	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VIM6	Gene names	Strc
Domain Architecture	No domain graphic available
Description	Stereocilin precursor.

SYN1_HUMAN
θ value	3.0926 (rank : 188)	NC score	0.067977 (rank : 199)
Query Neighborhood Hits	296	Target Neighborhood Hits	419	Shared Neighborhood Hits	62
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

WASIP_HUMAN
θ value	3.0926 (rank : 189)	NC score	0.110022 (rank : 57)
Query Neighborhood Hits	296	Target Neighborhood Hits	458	Shared Neighborhood Hits	68
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

YLPM1_HUMAN
θ value	3.0926 (rank : 190)	NC score	0.095751 (rank : 95)
Query Neighborhood Hits	296	Target Neighborhood Hits	670	Shared Neighborhood Hits	87
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

B4GN4_MOUSE
θ value	4.03905 (rank : 191)	NC score	0.036046 (rank : 372)
Query Neighborhood Hits	296	Target Neighborhood Hits	129	Shared Neighborhood Hits	25
SwissProt Accessions	Q766D5, Q8CHV2	Gene names	B4galnt4
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 1 (EC 2.4.1.244) (NGalNAc-T1) (Beta- 1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4).

BMX_MOUSE
θ value	4.03905 (rank : 192)	NC score	0.036736 (rank : 371)
Query Neighborhood Hits	296	Target Neighborhood Hits	912	Shared Neighborhood Hits	52
SwissProt Accessions	P97504	Gene names	Bmx
Domain Architecture	No domain graphic available
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein homolog).

COIA1_HUMAN
θ value	4.03905 (rank : 193)	NC score	0.037323 (rank : 368)
Query Neighborhood Hits	296	Target Neighborhood Hits	447	Shared Neighborhood Hits	51
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

CSKI1_HUMAN
θ value	4.03905 (rank : 194)	NC score	0.044943 (rank : 345)
Query Neighborhood Hits	296	Target Neighborhood Hits	997	Shared Neighborhood Hits	115
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

ENAH_HUMAN
θ value	4.03905 (rank : 195)	NC score	0.034996 (rank : 375)
Query Neighborhood Hits	296	Target Neighborhood Hits	784	Shared Neighborhood Hits	61
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

ESPL1_MOUSE
θ value	4.03905 (rank : 196)	NC score	0.022162 (rank : 418)
Query Neighborhood Hits	296	Target Neighborhood Hits	67	Shared Neighborhood Hits	11
SwissProt Accessions	P60330	Gene names	Espl1, Esp1, Kiaa0165
Domain Architecture
Description	Separin (EC 3.4.22.49) (Separase) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein).

FOG1_HUMAN
θ value	4.03905 (rank : 197)	NC score	0.020484 (rank : 425)
Query Neighborhood Hits	296	Target Neighborhood Hits	981	Shared Neighborhood Hits	51
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

FOXK1_MOUSE
θ value	4.03905 (rank : 198)	NC score	0.015240 (rank : 441)
Query Neighborhood Hits	296	Target Neighborhood Hits	215	Shared Neighborhood Hits	34
SwissProt Accessions	P42128, O35939	Gene names	Foxk1, Mnf
Domain Architecture
Description	Forkhead box protein K1 (Myocyte nuclear factor) (MNF).

GGA2_HUMAN
θ value	4.03905 (rank : 199)	NC score	0.019469 (rank : 427)
Query Neighborhood Hits	296	Target Neighborhood Hits	114	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UJY4, O14564, Q9NYN2, Q9UPS2	Gene names	GGA2, KIAA1080
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA2 (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (Gamma-adaptin-related protein 2) (VHS domain and ear domain of gamma-adaptin) (Vear).

HERC5_HUMAN
θ value	4.03905 (rank : 200)	NC score	0.008239 (rank : 457)
Query Neighborhood Hits	296	Target Neighborhood Hits	66	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UII4	Gene names	HERC5, CEB1, CEBP1
Domain Architecture
Description	HECT domain and RCC1-like domain-containing protein 5 (Cyclin-E- binding protein 1).

HME1_MOUSE
θ value	4.03905 (rank : 201)	NC score	0.012450 (rank : 447)
Query Neighborhood Hits	296	Target Neighborhood Hits	397	Shared Neighborhood Hits	21
SwissProt Accessions	P09065	Gene names	En1, En-1
Domain Architecture
Description	Homeobox protein engrailed-1 (Mo-En-1).

MCSP_MOUSE
θ value	4.03905 (rank : 202)	NC score	0.033560 (rank : 382)
Query Neighborhood Hits	296	Target Neighborhood Hits	108	Shared Neighborhood Hits	8
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

MYL4_HUMAN
θ value	4.03905 (rank : 203)	NC score	0.009413 (rank : 453)
Query Neighborhood Hits	296	Target Neighborhood Hits	66	Shared Neighborhood Hits	4
SwissProt Accessions	P12829, P11783	Gene names	MYL4, MLC1
Domain Architecture
Description	Myosin light polypeptide 4 (Myosin light chain 1, embryonic muscle/atrial isoform) (Myosin light chain alkali, GT-1 isoform).

PO6F2_HUMAN
θ value	4.03905 (rank : 204)	NC score	0.029925 (rank : 396)
Query Neighborhood Hits	296	Target Neighborhood Hits	618	Shared Neighborhood Hits	46
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

PO6F2_MOUSE
θ value	4.03905 (rank : 205)	NC score	0.032369 (rank : 388)
Query Neighborhood Hits	296	Target Neighborhood Hits	639	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

RFX1_MOUSE
θ value	4.03905 (rank : 206)	NC score	0.034113 (rank : 380)
Query Neighborhood Hits	296	Target Neighborhood Hits	181	Shared Neighborhood Hits	24
SwissProt Accessions	P48377	Gene names	Rfx1
Domain Architecture
Description	DNA-binding protein RFX1.

RGL2_HUMAN
θ value	4.03905 (rank : 207)	NC score	0.024535 (rank : 411)
Query Neighborhood Hits	296	Target Neighborhood Hits	45	Shared Neighborhood Hits	10
SwissProt Accessions	O15211, Q9Y3F3	Gene names	RGL2, RAB2L
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator-like 2 (RalGDS-like factor) (RAS-associated protein RAB2L).

RIN3_HUMAN
θ value	4.03905 (rank : 208)	NC score	0.056808 (rank : 262)
Query Neighborhood Hits	296	Target Neighborhood Hits	227	Shared Neighborhood Hits	41
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

SNPC4_MOUSE
θ value	4.03905 (rank : 209)	NC score	0.036019 (rank : 374)
Query Neighborhood Hits	296	Target Neighborhood Hits	237	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BP86, Q6PGG7, Q80UG9, Q810L1	Gene names	Snapc4
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit).

SOX13_MOUSE
θ value	4.03905 (rank : 210)	NC score	0.037120 (rank : 369)
Query Neighborhood Hits	296	Target Neighborhood Hits	495	Shared Neighborhood Hits	82
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

SOX17_MOUSE
θ value	4.03905 (rank : 211)	NC score	0.020768 (rank : 423)
Query Neighborhood Hits	296	Target Neighborhood Hits	223	Shared Neighborhood Hits	30
SwissProt Accessions	Q61473, Q61472, Q62248	Gene names	Sox17, Sox-17
Domain Architecture
Description	Transcription factor SOX-17.

SPRR3_HUMAN
θ value	4.03905 (rank : 212)	NC score	0.064963 (rank : 220)
Query Neighborhood Hits	296	Target Neighborhood Hits	102	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UBC9, O75597, Q4ZGI7, Q5T525, Q8NET7, Q9UDG3	Gene names	SPRR3, SPRC
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta) (Esophagin) (22 kDa pancornulin).

TRRAP_HUMAN
θ value	4.03905 (rank : 213)	NC score	0.020943 (rank : 421)
Query Neighborhood Hits	296	Target Neighborhood Hits	117	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y4A5, O75218, Q9Y631, Q9Y6H4	Gene names	TRRAP, PAF400
Domain Architecture
Description	Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog).

WASF1_HUMAN
θ value	4.03905 (rank : 214)	NC score	0.072008 (rank : 172)
Query Neighborhood Hits	296	Target Neighborhood Hits	260	Shared Neighborhood Hits	46
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

WFS1_MOUSE
θ value	4.03905 (rank : 215)	NC score	0.020929 (rank : 422)
Query Neighborhood Hits	296	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	P56695, Q9Z276	Gene names	Wfs1
Domain Architecture	No domain graphic available
Description	Wolframin.

AGT2_HUMAN
θ value	5.27518 (rank : 216)	NC score	0.031287 (rank : 390)
Query Neighborhood Hits	296	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BYV1, Q53FB4, Q53FY7, Q53G03, Q5W7Q1	Gene names	AGXT2, AGT2
Domain Architecture
Description	Alanine--glyoxylate aminotransferase 2, mitochondrial precursor (EC 2.6.1.44) ((R)-3-amino-2-methylpropionate--pyruvate transaminase) (EC 2.6.1.40) (AGT 2) (Beta-alanine-pyruvate aminotransferase) (Beta- ALAAT II) (D-AIBAT).

CCNK_MOUSE
θ value	5.27518 (rank : 217)	NC score	0.072532 (rank : 170)
Query Neighborhood Hits	296	Target Neighborhood Hits	350	Shared Neighborhood Hits	57
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

FGD6_HUMAN
θ value	5.27518 (rank : 218)	NC score	0.080275 (rank : 140)
Query Neighborhood Hits	296	Target Neighborhood Hits	237	Shared Neighborhood Hits	37
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

FOXQ1_HUMAN
θ value	5.27518 (rank : 219)	NC score	0.008674 (rank : 456)
Query Neighborhood Hits	296	Target Neighborhood Hits	115	Shared Neighborhood Hits	9
SwissProt Accessions	Q9C009, Q9NS06	Gene names	FOXQ1, HFH1
Domain Architecture
Description	Forkhead box protein Q1 (Hepatocyte nuclear factor 3 forkhead homolog 1) (HNF-3/forkhead-like protein 1) (HFH-1).

GCH1_HUMAN
θ value	5.27518 (rank : 220)	NC score	0.033419 (rank : 384)
Query Neighborhood Hits	296	Target Neighborhood Hits	69	Shared Neighborhood Hits	11
SwissProt Accessions	P30793, Q9Y4I8	Gene names	GCH1, DYT5, GCH
Domain Architecture
Description	GTP cyclohydrolase I (EC 3.5.4.16) (GTP-CH-I).

GGN_HUMAN
θ value	5.27518 (rank : 221)	NC score	0.098920 (rank : 85)
Query Neighborhood Hits	296	Target Neighborhood Hits	269	Shared Neighborhood Hits	50
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

IASPP_MOUSE
θ value	5.27518 (rank : 222)	NC score	0.060438 (rank : 245)
Query Neighborhood Hits	296	Target Neighborhood Hits	1024	Shared Neighborhood Hits	118
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

IL3RB_HUMAN
θ value	5.27518 (rank : 223)	NC score	0.037100 (rank : 370)
Query Neighborhood Hits	296	Target Neighborhood Hits	163	Shared Neighborhood Hits	25
SwissProt Accessions	P32927	Gene names	CSF2RB, IL3RB, IL5RB
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen) (CDw131).

MUCDL_MOUSE
θ value	5.27518 (rank : 224)	NC score	0.033447 (rank : 383)
Query Neighborhood Hits	296	Target Neighborhood Hits	461	Shared Neighborhood Hits	45
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

PCD16_HUMAN
θ value	5.27518 (rank : 225)	NC score	0.005429 (rank : 458)
Query Neighborhood Hits	296	Target Neighborhood Hits	245	Shared Neighborhood Hits	11
SwissProt Accessions	Q96JQ0, O15098	Gene names	DCHS1, CDH19, FIB1, KIAA1773, PCDH16
Domain Architecture
Description	Protocadherin-16 precursor (Dachsous 1) (Cadherin-19) (Fibroblast cadherin 1).

PELP1_HUMAN
θ value	5.27518 (rank : 226)	NC score	0.053472 (rank : 296)
Query Neighborhood Hits	296	Target Neighborhood Hits	596	Shared Neighborhood Hits	47
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

RCOR3_MOUSE
θ value	5.27518 (rank : 227)	NC score	0.053405 (rank : 297)
Query Neighborhood Hits	296	Target Neighborhood Hits	110	Shared Neighborhood Hits	21
SwissProt Accessions	Q6PGA0	Gene names	Rcor3
Domain Architecture	No domain graphic available
Description	REST corepressor 3.

REEP4_HUMAN
θ value	5.27518 (rank : 228)	NC score	0.011530 (rank : 449)
Query Neighborhood Hits	296	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H6H4, Q86VL1, Q9H6I5, Q9HBP4	Gene names	REEP4, C8orf20
Domain Architecture	No domain graphic available
Description	Receptor expression-enhancing protein 4.

SF3A1_MOUSE
θ value	5.27518 (rank : 229)	NC score	0.044572 (rank : 347)
Query Neighborhood Hits	296	Target Neighborhood Hits	198	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K4Z5, Q8C0M7, Q8C128, Q8C175, Q921T3	Gene names	Sf3a1
Domain Architecture	No domain graphic available
Description	Splicing factor 3 subunit 1 (SF3a120).

SFPQ_HUMAN
θ value	5.27518 (rank : 230)	NC score	0.066442 (rank : 204)
Query Neighborhood Hits	296	Target Neighborhood Hits	986	Shared Neighborhood Hits	80
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

TCRG1_HUMAN
θ value	5.27518 (rank : 231)	NC score	0.040447 (rank : 361)
Query Neighborhood Hits	296	Target Neighborhood Hits	929	Shared Neighborhood Hits	58
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

VAV2_HUMAN
θ value	5.27518 (rank : 232)	NC score	0.060530 (rank : 244)
Query Neighborhood Hits	296	Target Neighborhood Hits	453	Shared Neighborhood Hits	43
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

ZDHC8_HUMAN
θ value	5.27518 (rank : 233)	NC score	0.024199 (rank : 413)
Query Neighborhood Hits	296	Target Neighborhood Hits	234	Shared Neighborhood Hits	36
SwissProt Accessions	Q9ULC8, Q6ICL1, Q6ZNF5, Q7Z6L9	Gene names	ZDHHC8, KIAA1292, ZDHHCL1, ZNF378
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8) (Zinc finger protein 378).

ZN207_HUMAN
θ value	5.27518 (rank : 234)	NC score	0.068430 (rank : 195)
Query Neighborhood Hits	296	Target Neighborhood Hits	326	Shared Neighborhood Hits	28
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

ZN628_HUMAN
θ value	5.27518 (rank : 235)	NC score	0.001532 (rank : 464)
Query Neighborhood Hits	296	Target Neighborhood Hits	814	Shared Neighborhood Hits	24
SwissProt Accessions	Q5EBL2, Q86X34	Gene names	ZNF628
Domain Architecture	No domain graphic available
Description	Zinc finger protein 628.

AKAP1_HUMAN
θ value	6.88961 (rank : 236)	NC score	0.015353 (rank : 440)
Query Neighborhood Hits	296	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	Q92667, Q13320, Q9BW14	Gene names	AKAP1, AKAP149
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (A-kinase anchor protein 149 kDa) (AKAP 149) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein 84) (S-AKAP84).

AMOT_HUMAN
θ value	6.88961 (rank : 237)	NC score	0.032610 (rank : 386)
Query Neighborhood Hits	296	Target Neighborhood Hits	712	Shared Neighborhood Hits	50
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

BRD4_MOUSE
θ value	6.88961 (rank : 238)	NC score	0.056557 (rank : 265)
Query Neighborhood Hits	296	Target Neighborhood Hits	845	Shared Neighborhood Hits	60
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

CABIN_HUMAN
θ value	6.88961 (rank : 239)	NC score	0.058351 (rank : 255)
Query Neighborhood Hits	296	Target Neighborhood Hits	490	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

CECR2_HUMAN
θ value	6.88961 (rank : 240)	NC score	0.062494 (rank : 234)
Query Neighborhood Hits	296	Target Neighborhood Hits	543	Shared Neighborhood Hits	84
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

CELR2_HUMAN
θ value	6.88961 (rank : 241)	NC score	0.004213 (rank : 461)
Query Neighborhood Hits	296	Target Neighborhood Hits	657	Shared Neighborhood Hits	17
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

CJ047_MOUSE
θ value	6.88961 (rank : 242)	NC score	0.030876 (rank : 393)
Query Neighborhood Hits	296	Target Neighborhood Hits	76	Shared Neighborhood Hits	15
SwissProt Accessions	Q8C5R2, Q8R017, Q8R2Z9	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf47 homolog.

CUTL2_MOUSE
θ value	6.88961 (rank : 243)	NC score	0.020720 (rank : 424)
Query Neighborhood Hits	296	Target Neighborhood Hits	771	Shared Neighborhood Hits	45
SwissProt Accessions	P70298	Gene names	Cutl2
Domain Architecture
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

DIAP1_HUMAN
θ value	6.88961 (rank : 244)	NC score	0.084980 (rank : 118)
Query Neighborhood Hits	296	Target Neighborhood Hits	784	Shared Neighborhood Hits	67
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

EPN1_MOUSE
θ value	6.88961 (rank : 245)	NC score	0.040953 (rank : 359)
Query Neighborhood Hits	296	Target Neighborhood Hits	240	Shared Neighborhood Hits	37
SwissProt Accessions	Q80VP1, O70446	Gene names	Epn1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (Intersectin-EH-binding protein 1) (Ibp1).

ERBB2_MOUSE
θ value	6.88961 (rank : 246)	NC score	0.023856 (rank : 414)
Query Neighborhood Hits	296	Target Neighborhood Hits	918	Shared Neighborhood Hits	32
SwissProt Accessions	P70424, Q61525, Q6ZPE0	Gene names	Erbb2, Kiaa3023, Neu
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene).

FOXL2_HUMAN
θ value	6.88961 (rank : 247)	NC score	0.011108 (rank : 452)
Query Neighborhood Hits	296	Target Neighborhood Hits	142	Shared Neighborhood Hits	17
SwissProt Accessions	P58012, Q4ZGJ3	Gene names	FOXL2
Domain Architecture
Description	Forkhead box protein L2.

GR65_HUMAN
θ value	6.88961 (rank : 248)	NC score	0.034535 (rank : 378)
Query Neighborhood Hits	296	Target Neighborhood Hits	148	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BQQ3, Q8N272, Q96H42	Gene names	GORASP1, GRASP65
Domain Architecture	No domain graphic available
Description	Golgi reassembly-stacking protein 1 (Golgi reassembly-stacking protein of 65 kDa) (GRASP65) (Golgi peripheral membrane protein p65) (Golgi phosphoprotein 5) (GOLPH5).

IWS1_HUMAN
θ value	6.88961 (rank : 249)	NC score	0.053996 (rank : 290)
Query Neighborhood Hits	296	Target Neighborhood Hits	1241	Shared Neighborhood Hits	83
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

KLF16_HUMAN
θ value	6.88961 (rank : 250)	NC score	-0.000067 (rank : 467)
Query Neighborhood Hits	296	Target Neighborhood Hits	737	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BXK1	Gene names	KLF16, BTEB4, NSLP2
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 16 (Transcription factor BTEB4) (Basic transcription element-binding protein 4) (BTE-binding protein 4) (Novel Sp1-like zinc finger transcription factor 2) (Transcription factor NSLP2).

M4K4_HUMAN
θ value	6.88961 (rank : 251)	NC score	0.011526 (rank : 450)
Query Neighborhood Hits	296	Target Neighborhood Hits	1589	Shared Neighborhood Hits	44
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

MYST3_MOUSE
θ value	6.88961 (rank : 252)	NC score	0.034626 (rank : 377)
Query Neighborhood Hits	296	Target Neighborhood Hits	688	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

PF21A_HUMAN
θ value	6.88961 (rank : 253)	NC score	0.027737 (rank : 405)
Query Neighborhood Hits	296	Target Neighborhood Hits	303	Shared Neighborhood Hits	20
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

PF21A_MOUSE
θ value	6.88961 (rank : 254)	NC score	0.026938 (rank : 406)
Query Neighborhood Hits	296	Target Neighborhood Hits	285	Shared Neighborhood Hits	18
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

PLCG2_HUMAN
θ value	6.88961 (rank : 255)	NC score	0.055264 (rank : 278)
Query Neighborhood Hits	296	Target Neighborhood Hits	280	Shared Neighborhood Hits	29
SwissProt Accessions	P16885, Q969T5	Gene names	PLCG2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV).

POGZ_MOUSE
θ value	6.88961 (rank : 256)	NC score	0.003575 (rank : 463)
Query Neighborhood Hits	296	Target Neighborhood Hits	765	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BZH4, Q4VA94, Q80TZ8, Q8C0K1, Q8K294	Gene names	Pogz, Kiaa0461
Domain Architecture
Description	Pogo transposable element with ZNF domain.

PRP2_MOUSE
θ value	6.88961 (rank : 257)	NC score	0.103080 (rank : 72)
Query Neighborhood Hits	296	Target Neighborhood Hits	347	Shared Neighborhood Hits	51
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

RAD9A_MOUSE
θ value	6.88961 (rank : 258)	NC score	0.018402 (rank : 431)
Query Neighborhood Hits	296	Target Neighborhood Hits	47	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z0F6, Q8QZZ3	Gene names	Rad9a, Rad9
Domain Architecture	No domain graphic available
Description	Cell cycle checkpoint control protein RAD9A (EC 3.1.11.2) (DNA repair exonuclease rad9 homolog A) (Rad9-like protein) (mRAD9).

RBM12_MOUSE
θ value	6.88961 (rank : 259)	NC score	0.053210 (rank : 300)
Query Neighborhood Hits	296	Target Neighborhood Hits	313	Shared Neighborhood Hits	41
SwissProt Accessions	Q8R4X3, Q8K373, Q8R302, Q9CS80	Gene names	Rbm12
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

S2A4R_HUMAN
θ value	6.88961 (rank : 260)	NC score	0.034955 (rank : 376)
Query Neighborhood Hits	296	Target Neighborhood Hits	54	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NR83, Q6F6I6, Q6F6I7, Q6GTK5, Q8TAH5, Q8WVW7, Q96QD3, Q9BV85	Gene names	SLC2A4RG, HDBP1
Domain Architecture	No domain graphic available
Description	SLC2A4 regulator (GLUT4 enhancer factor) (GEF) (Huntington disease gene regulatory region-binding protein 1) (HDBP-1).

SC24A_MOUSE
θ value	6.88961 (rank : 261)	NC score	0.062472 (rank : 235)
Query Neighborhood Hits	296	Target Neighborhood Hits	394	Shared Neighborhood Hits	82
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

SF3A1_HUMAN
θ value	6.88961 (rank : 262)	NC score	0.045946 (rank : 341)
Query Neighborhood Hits	296	Target Neighborhood Hits	199	Shared Neighborhood Hits	33
SwissProt Accessions	Q15459	Gene names	SF3A1, SAP114
Domain Architecture
Description	Splicing factor 3 subunit 1 (Spliceosome-associated protein 114) (SAP 114) (SF3a120).

SF3B4_HUMAN
θ value	6.88961 (rank : 263)	NC score	0.032998 (rank : 385)
Query Neighborhood Hits	296	Target Neighborhood Hits	445	Shared Neighborhood Hits	44
SwissProt Accessions	Q15427	Gene names	SF3B4, SAP49
Domain Architecture
Description	Splicing factor 3B subunit 4 (Spliceosome-associated protein 49) (SAP 49) (SF3b50) (Pre-mRNA-splicing factor SF3b 49 kDa subunit).

SYNJ1_HUMAN
θ value	6.88961 (rank : 264)	NC score	0.051573 (rank : 320)
Query Neighborhood Hits	296	Target Neighborhood Hits	498	Shared Neighborhood Hits	75
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

TCGAP_HUMAN
θ value	6.88961 (rank : 265)	NC score	0.086324 (rank : 115)
Query Neighborhood Hits	296	Target Neighborhood Hits	872	Shared Neighborhood Hits	122
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TNK1_MOUSE
θ value	6.88961 (rank : 266)	NC score	0.025390 (rank : 410)
Query Neighborhood Hits	296	Target Neighborhood Hits	806	Shared Neighborhood Hits	27
SwissProt Accessions	Q99ML2, Q8CCC4, Q8K0X9, Q91V11	Gene names	Tnk1, Kos1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (Kinase of embryonic stem cells).

TTBK1_HUMAN
θ value	6.88961 (rank : 267)	NC score	0.021639 (rank : 420)
Query Neighborhood Hits	296	Target Neighborhood Hits	1058	Shared Neighborhood Hits	60
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

UBQL3_HUMAN
θ value	6.88961 (rank : 268)	NC score	0.017229 (rank : 435)
Query Neighborhood Hits	296	Target Neighborhood Hits	141	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H347, Q9NRE0	Gene names	UBQLN3
Domain Architecture
Description	Ubiquilin-3.

WASF1_MOUSE
θ value	6.88961 (rank : 269)	NC score	0.070477 (rank : 184)
Query Neighborhood Hits	296	Target Neighborhood Hits	261	Shared Neighborhood Hits	43
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

YTHD1_HUMAN
θ value	6.88961 (rank : 270)	NC score	0.016008 (rank : 438)
Query Neighborhood Hits	296	Target Neighborhood Hits	71	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BYJ9, Q8N3G5, Q8TBT1, Q96AN4, Q96S57, Q9BTI7, Q9NX79	Gene names	YTHDF1, C20orf21
Domain Architecture
Description	YTH domain family protein 1 (Dermatomyositis associated with cancer putative autoantigen 1) (DACA-1).

ZDHC8_MOUSE
θ value	6.88961 (rank : 271)	NC score	0.018035 (rank : 432)
Query Neighborhood Hits	296	Target Neighborhood Hits	243	Shared Neighborhood Hits	25
SwissProt Accessions	Q5Y5T5, Q7TNF7	Gene names	Zdhhc8
Domain Architecture	No domain graphic available
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8).

ATS8_HUMAN
θ value	8.99809 (rank : 272)	NC score	0.001166 (rank : 466)
Query Neighborhood Hits	296	Target Neighborhood Hits	145	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UP79, Q9NZS0	Gene names	ADAMTS8, METH2
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2) (METH- 8).

CA106_HUMAN
θ value	8.99809 (rank : 273)	NC score	0.030258 (rank : 394)
Query Neighborhood Hits	296	Target Neighborhood Hits	124	Shared Neighborhood Hits	14
SwissProt Accessions	Q3KP66, Q9NV65, Q9NVI0	Gene names	C1orf106
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106.

CCD1A_MOUSE
θ value	8.99809 (rank : 274)	NC score	0.014883 (rank : 442)
Query Neighborhood Hits	296	Target Neighborhood Hits	83	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K1A6, Q2MJB5, Q8R3Z4	Gene names	Cc2d1a
Domain Architecture	No domain graphic available
Description	Coiled-coil and C2 domain-containing protein 1A (Five repressor element under dual repression-binding protein 1) (FRE under dual repression-binding protein 1) (Freud-1).

CELR2_MOUSE
θ value	8.99809 (rank : 275)	NC score	0.004099 (rank : 462)
Query Neighborhood Hits	296	Target Neighborhood Hits	584	Shared Neighborhood Hits	14
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

CENG2_MOUSE
θ value	8.99809 (rank : 276)	NC score	0.036039 (rank : 373)
Query Neighborhood Hits	296	Target Neighborhood Hits	463	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

DIAP2_HUMAN
θ value	8.99809 (rank : 277)	NC score	0.066625 (rank : 202)
Query Neighborhood Hits	296	Target Neighborhood Hits	342	Shared Neighborhood Hits	43
SwissProt Accessions	O60879, O60878, Q8WX06, Q8WX48, Q9UJL2	Gene names	DIAPH2, DIA
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2).

DMRTA_HUMAN
θ value	8.99809 (rank : 278)	NC score	0.012751 (rank : 446)
Query Neighborhood Hits	296	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q5VZB9, Q8N8Y9, Q9H4B9	Gene names	DMRTA1, DMO
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor A1.

FA53C_HUMAN
θ value	8.99809 (rank : 279)	NC score	0.016609 (rank : 437)
Query Neighborhood Hits	296	Target Neighborhood Hits	29	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NYF3	Gene names	FAM53C, C5orf6
Domain Architecture	No domain graphic available
Description	Protein FAM53C.

HXA3_MOUSE
θ value	8.99809 (rank : 280)	NC score	0.016628 (rank : 436)
Query Neighborhood Hits	296	Target Neighborhood Hits	558	Shared Neighborhood Hits	50
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

HXD9_HUMAN
θ value	8.99809 (rank : 281)	NC score	0.004386 (rank : 460)
Query Neighborhood Hits	296	Target Neighborhood Hits	352	Shared Neighborhood Hits	12
SwissProt Accessions	P28356	Gene names	HOXD9, HOX4C
Domain Architecture
Description	Homeobox protein Hox-D9 (Hox-4C) (Hox-5.2).

IRX3_HUMAN
θ value	8.99809 (rank : 282)	NC score	0.020399 (rank : 426)
Query Neighborhood Hits	296	Target Neighborhood Hits	342	Shared Neighborhood Hits	26
SwissProt Accessions	P78415, Q7Z4A4, Q7Z4A5, Q8IVC6	Gene names	IRX3, IRXB1
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-3 (Iroquois homeobox protein 3) (Homeodomain protein IRXB1).

MAP1A_HUMAN
θ value	8.99809 (rank : 283)	NC score	0.055011 (rank : 282)
Query Neighborhood Hits	296	Target Neighborhood Hits	1626	Shared Neighborhood Hits	132
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MINT_HUMAN
θ value	8.99809 (rank : 284)	NC score	0.050582 (rank : 333)
Query Neighborhood Hits	296	Target Neighborhood Hits	1291	Shared Neighborhood Hits	88
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MNT_HUMAN
θ value	8.99809 (rank : 285)	NC score	0.071298 (rank : 178)
Query Neighborhood Hits	296	Target Neighborhood Hits	496	Shared Neighborhood Hits	84
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

NCOR2_MOUSE
θ value	8.99809 (rank : 286)	NC score	0.061945 (rank : 236)
Query Neighborhood Hits	296	Target Neighborhood Hits	790	Shared Neighborhood Hits	72
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

NUMBL_HUMAN
θ value	8.99809 (rank : 287)	NC score	0.070573 (rank : 183)
Query Neighborhood Hits	296	Target Neighborhood Hits	394	Shared Neighborhood Hits	89
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

NUP53_MOUSE
θ value	8.99809 (rank : 288)	NC score	0.051304 (rank : 324)
Query Neighborhood Hits	296	Target Neighborhood Hits	94	Shared Neighborhood Hits	20
SwissProt Accessions	Q8R4R6, Q9D7J2	Gene names	Nup35, Mp44, Nup53
Domain Architecture	No domain graphic available
Description	Nucleoporin NUP53 (Nuclear pore complex protein Nup53) (Nucleoporin Nup35) (35 kDa nucleoporin) (Mitotic phosphoprotein 44) (MP-44).

P53_HUMAN
θ value	8.99809 (rank : 289)	NC score	0.011414 (rank : 451)
Query Neighborhood Hits	296	Target Neighborhood Hits	42	Shared Neighborhood Hits	5
SwissProt Accessions	P04637, Q15086, Q15087, Q15088, Q16535, Q16807, Q16808, Q16809, Q16810, Q16811, Q16848, Q86UG1, Q8J016, Q99659, Q9BTM4, Q9HAQ8, Q9NP68, Q9NPJ2, Q9NZD0, Q9UBI2, Q9UQ61	Gene names	TP53, P53
Domain Architecture
Description	Cellular tumor antigen p53 (Tumor suppressor p53) (Phosphoprotein p53) (Antigen NY-CO-13).

RBM12_HUMAN
θ value	8.99809 (rank : 290)	NC score	0.040063 (rank : 363)
Query Neighborhood Hits	296	Target Neighborhood Hits	298	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NTZ6, O94865, Q8N3B1, Q9H196	Gene names	RBM12, KIAA0765
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

SF04_MOUSE
θ value	8.99809 (rank : 291)	NC score	0.030187 (rank : 395)
Query Neighborhood Hits	296	Target Neighborhood Hits	95	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CH02, Q8R094	Gene names	Sf4
Domain Architecture	No domain graphic available
Description	Splicing factor 4.

SHAN2_HUMAN
θ value	8.99809 (rank : 292)	NC score	0.023431 (rank : 416)
Query Neighborhood Hits	296	Target Neighborhood Hits	346	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

SRRM1_MOUSE
θ value	8.99809 (rank : 293)	NC score	0.097853 (rank : 92)
Query Neighborhood Hits	296	Target Neighborhood Hits	966	Shared Neighborhood Hits	106
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SYN3_HUMAN
θ value	8.99809 (rank : 294)	NC score	0.041224 (rank : 358)
Query Neighborhood Hits	296	Target Neighborhood Hits	203	Shared Neighborhood Hits	35
SwissProt Accessions	O14994	Gene names	SYN3
Domain Architecture
Description	Synapsin-3 (Synapsin III).

TP53B_MOUSE
θ value	8.99809 (rank : 295)	NC score	0.057796 (rank : 257)
Query Neighborhood Hits	296	Target Neighborhood Hits	644	Shared Neighborhood Hits	63
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

ZN219_HUMAN
θ value	8.99809 (rank : 296)	NC score	0.004930 (rank : 459)
Query Neighborhood Hits	296	Target Neighborhood Hits	876	Shared Neighborhood Hits	39
SwissProt Accessions	Q9P2Y4, Q8IYC1, Q9BW28	Gene names	ZNF219
Domain Architecture	No domain graphic available
Description	Zinc finger protein 219.

3BP1_MOUSE
θ value	θ > 10 (rank : 297)	NC score	0.052110 (rank : 313)
Query Neighborhood Hits	296	Target Neighborhood Hits	238	Shared Neighborhood Hits	37
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

AB1IP_MOUSE
θ value	θ > 10 (rank : 298)	NC score	0.054553 (rank : 286)
Query Neighborhood Hits	296	Target Neighborhood Hits	181	Shared Neighborhood Hits	35
SwissProt Accessions	Q8R5A3, O35329, Q8BRU0, Q99KV8	Gene names	Apbb1ip, Prel1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 48).

ALEX_HUMAN
θ value	θ > 10 (rank : 299)	NC score	0.060739 (rank : 242)
Query Neighborhood Hits	296	Target Neighborhood Hits	361	Shared Neighborhood Hits	57
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

ALEX_MOUSE
θ value	θ > 10 (rank : 300)	NC score	0.051763 (rank : 319)
Query Neighborhood Hits	296	Target Neighborhood Hits	197	Shared Neighborhood Hits	37
SwissProt Accessions	Q6R0H6, Q8BIR3	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

ANLN_HUMAN
θ value	θ > 10 (rank : 301)	NC score	0.079339 (rank : 142)
Query Neighborhood Hits	296	Target Neighborhood Hits	222	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NQW6, Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0	Gene names	ANLN
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

ANLN_MOUSE
θ value	θ > 10 (rank : 302)	NC score	0.065333 (rank : 215)
Query Neighborhood Hits	296	Target Neighborhood Hits	297	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K298, Q8BL79, Q8BLB3, Q8K2N0, Q9CUY0	Gene names	Anln
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

ARHGF_HUMAN
θ value	θ > 10 (rank : 303)	NC score	0.052320 (rank : 311)
Query Neighborhood Hits	296	Target Neighborhood Hits	214	Shared Neighborhood Hits	43
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

ARI1A_HUMAN
θ value	θ > 10 (rank : 304)	NC score	0.060613 (rank : 243)
Query Neighborhood Hits	296	Target Neighborhood Hits	787	Shared Neighborhood Hits	94
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

ATN1_HUMAN
θ value	θ > 10 (rank : 305)	NC score	0.087505 (rank : 113)
Query Neighborhood Hits	296	Target Neighborhood Hits	676	Shared Neighborhood Hits	73
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

BAG3_MOUSE
θ value	θ > 10 (rank : 306)	NC score	0.069421 (rank : 189)
Query Neighborhood Hits	296	Target Neighborhood Hits	513	Shared Neighborhood Hits	88
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

BASP_HUMAN
θ value	θ > 10 (rank : 307)	NC score	0.052608 (rank : 309)
Query Neighborhood Hits	296	Target Neighborhood Hits	321	Shared Neighborhood Hits	30
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BASP_MOUSE
θ value	θ > 10 (rank : 308)	NC score	0.051104 (rank : 329)
Query Neighborhood Hits	296	Target Neighborhood Hits	260	Shared Neighborhood Hits	26
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BAT3_MOUSE
θ value	θ > 10 (rank : 309)	NC score	0.059493 (rank : 251)
Query Neighborhood Hits	296	Target Neighborhood Hits	518	Shared Neighborhood Hits	83
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

BCAR1_HUMAN
θ value	θ > 10 (rank : 310)	NC score	0.053211 (rank : 299)
Query Neighborhood Hits	296	Target Neighborhood Hits	554	Shared Neighborhood Hits	103
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

BCL9_HUMAN
θ value	θ > 10 (rank : 311)	NC score	0.101019 (rank : 76)
Query Neighborhood Hits	296	Target Neighborhood Hits	1008	Shared Neighborhood Hits	151
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

BCL9_MOUSE
θ value	θ > 10 (rank : 312)	NC score	0.087076 (rank : 114)
Query Neighborhood Hits	296	Target Neighborhood Hits	770	Shared Neighborhood Hits	124
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

BIG1_HUMAN
θ value	θ > 10 (rank : 313)	NC score	0.107241 (rank : 62)
Query Neighborhood Hits	296	Target Neighborhood Hits	76	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y6D6, Q9NV46, Q9UFV2, Q9UNL0	Gene names	ARFGEF1, ARFGEP1, BIG1
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Brefeldin A-inhibited GEP 1) (p200 ARF-GEP1) (p200 ARF guanine nucleotide exchange factor).

BIG2_HUMAN
θ value	θ > 10 (rank : 314)	NC score	0.107587 (rank : 61)
Query Neighborhood Hits	296	Target Neighborhood Hits	66	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y6D5, Q5TFT9, Q9NTS1	Gene names	ARFGEF2, ARFGEP2, BIG2
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (Brefeldin A-inhibited GEP 2).

BSN_HUMAN
θ value	θ > 10 (rank : 315)	NC score	0.071855 (rank : 173)
Query Neighborhood Hits	296	Target Neighborhood Hits	1537	Shared Neighborhood Hits	134
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

BSN_MOUSE
θ value	θ > 10 (rank : 316)	NC score	0.081535 (rank : 134)
Query Neighborhood Hits	296	Target Neighborhood Hits	2057	Shared Neighborhood Hits	165
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

C43BP_MOUSE
θ value	θ > 10 (rank : 317)	NC score	0.053865 (rank : 292)
Query Neighborhood Hits	296	Target Neighborhood Hits	91	Shared Neighborhood Hits	30
SwissProt Accessions	Q9EQG9, Q91WB1, Q9CU52, Q9EQG8	Gene names	Col4a3bp, Stard11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

CASC3_MOUSE
θ value	θ > 10 (rank : 318)	NC score	0.052892 (rank : 304)
Query Neighborhood Hits	296	Target Neighborhood Hits	333	Shared Neighborhood Hits	47
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

CBP_HUMAN
θ value	θ > 10 (rank : 319)	NC score	0.071021 (rank : 182)
Query Neighborhood Hits	296	Target Neighborhood Hits	941	Shared Neighborhood Hits	114
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CD2_HUMAN
θ value	θ > 10 (rank : 320)	NC score	0.076895 (rank : 154)
Query Neighborhood Hits	296	Target Neighborhood Hits	504	Shared Neighborhood Hits	100
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

CDN1C_HUMAN
θ value	θ > 10 (rank : 321)	NC score	0.055220 (rank : 279)
Query Neighborhood Hits	296	Target Neighborhood Hits	168	Shared Neighborhood Hits	29
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

CEL_HUMAN
θ value	θ > 10 (rank : 322)	NC score	0.080307 (rank : 139)
Query Neighborhood Hits	296	Target Neighborhood Hits	896	Shared Neighborhood Hits	133
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

CENA1_HUMAN
θ value	θ > 10 (rank : 323)	NC score	0.078184 (rank : 146)
Query Neighborhood Hits	296	Target Neighborhood Hits	87	Shared Neighborhood Hits	41
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

CENB1_HUMAN
θ value	θ > 10 (rank : 324)	NC score	0.070051 (rank : 187)
Query Neighborhood Hits	296	Target Neighborhood Hits	383	Shared Neighborhood Hits	44
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

CENB2_HUMAN
θ value	θ > 10 (rank : 325)	NC score	0.085265 (rank : 117)
Query Neighborhood Hits	296	Target Neighborhood Hits	425	Shared Neighborhood Hits	48
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

CENB5_HUMAN
θ value	θ > 10 (rank : 326)	NC score	0.077624 (rank : 149)
Query Neighborhood Hits	296	Target Neighborhood Hits	395	Shared Neighborhood Hits	42
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

CEND1_HUMAN
θ value	θ > 10 (rank : 327)	NC score	0.077470 (rank : 151)
Query Neighborhood Hits	296	Target Neighborhood Hits	284	Shared Neighborhood Hits	47
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

CEND1_MOUSE
θ value	θ > 10 (rank : 328)	NC score	0.064506 (rank : 226)
Query Neighborhood Hits	296	Target Neighborhood Hits	260	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

CIC_HUMAN
θ value	θ > 10 (rank : 329)	NC score	0.063244 (rank : 230)
Query Neighborhood Hits	296	Target Neighborhood Hits	992	Shared Neighborhood Hits	120
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CJ078_MOUSE
θ value	θ > 10 (rank : 330)	NC score	0.055807 (rank : 271)
Query Neighborhood Hits	296	Target Neighborhood Hits	559	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

CK024_HUMAN
θ value	θ > 10 (rank : 331)	NC score	0.076574 (rank : 158)
Query Neighborhood Hits	296	Target Neighborhood Hits	408	Shared Neighborhood Hits	63
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

CN032_HUMAN
θ value	θ > 10 (rank : 332)	NC score	0.066011 (rank : 207)
Query Neighborhood Hits	296	Target Neighborhood Hits	267	Shared Neighborhood Hits	34
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

CN032_MOUSE
θ value	θ > 10 (rank : 333)	NC score	0.065585 (rank : 211)
Query Neighborhood Hits	296	Target Neighborhood Hits	233	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

CN155_HUMAN
θ value	θ > 10 (rank : 334)	NC score	0.064830 (rank : 224)
Query Neighborhood Hits	296	Target Neighborhood Hits	385	Shared Neighborhood Hits	43
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

CNKR1_HUMAN
θ value	θ > 10 (rank : 335)	NC score	0.143426 (rank : 32)
Query Neighborhood Hits	296	Target Neighborhood Hits	154	Shared Neighborhood Hits	36
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

CNKR2_HUMAN
θ value	θ > 10 (rank : 336)	NC score	0.105074 (rank : 70)
Query Neighborhood Hits	296	Target Neighborhood Hits	197	Shared Neighborhood Hits	35
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_MOUSE
θ value	θ > 10 (rank : 337)	NC score	0.105218 (rank : 69)
Query Neighborhood Hits	296	Target Neighborhood Hits	197	Shared Neighborhood Hits	35
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CO039_MOUSE
θ value	θ > 10 (rank : 338)	NC score	0.065666 (rank : 208)
Query Neighborhood Hits	296	Target Neighborhood Hits	445	Shared Neighborhood Hits	83
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

CRSP2_HUMAN
θ value	θ > 10 (rank : 339)	NC score	0.052369 (rank : 310)
Query Neighborhood Hits	296	Target Neighborhood Hits	380	Shared Neighborhood Hits	72
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

CS016_HUMAN
θ value	θ > 10 (rank : 340)	NC score	0.056478 (rank : 267)
Query Neighborhood Hits	296	Target Neighborhood Hits	310	Shared Neighborhood Hits	45
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

DAAM1_MOUSE
θ value	θ > 10 (rank : 341)	NC score	0.053601 (rank : 294)
Query Neighborhood Hits	296	Target Neighborhood Hits	443	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BPM0, Q80Y68, Q9CQQ2	Gene names	Daam1
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

DAAM2_HUMAN
θ value	θ > 10 (rank : 342)	NC score	0.053582 (rank : 295)
Query Neighborhood Hits	296	Target Neighborhood Hits	350	Shared Neighborhood Hits	21
SwissProt Accessions	Q86T65, Q5T4U0, Q9NQI5, Q9Y4G0	Gene names	DAAM2, KIAA0381
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 2.

DGKH_HUMAN
θ value	θ > 10 (rank : 343)	NC score	0.057557 (rank : 258)
Query Neighborhood Hits	296	Target Neighborhood Hits	255	Shared Neighborhood Hits	42
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

DGKK_HUMAN
θ value	θ > 10 (rank : 344)	NC score	0.061182 (rank : 239)
Query Neighborhood Hits	296	Target Neighborhood Hits	378	Shared Neighborhood Hits	52
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

DIAP2_MOUSE
θ value	θ > 10 (rank : 345)	NC score	0.065604 (rank : 210)
Query Neighborhood Hits	296	Target Neighborhood Hits	260	Shared Neighborhood Hits	39
SwissProt Accessions	O70566, Q8C2G8	Gene names	Diaph2, Diap2
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2) (mDia3).

DIAP3_HUMAN
θ value	θ > 10 (rank : 346)	NC score	0.051789 (rank : 317)
Query Neighborhood Hits	296	Target Neighborhood Hits	209	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NSV4, Q5T2S7, Q5XKF6, Q6MZF0, Q6NUP0, Q86VS4, Q8NAV4	Gene names	DIAPH3, DIAP3
Domain Architecture	No domain graphic available
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3).

DIAP3_MOUSE
θ value	θ > 10 (rank : 347)	NC score	0.052752 (rank : 307)
Query Neighborhood Hits	296	Target Neighborhood Hits	221	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z207	Gene names	Diaph3, Diap3
Domain Architecture
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3) (mDIA2) (p134mDIA2).

DIDO1_HUMAN
θ value	θ > 10 (rank : 348)	NC score	0.059821 (rank : 248)
Query Neighborhood Hits	296	Target Neighborhood Hits	960	Shared Neighborhood Hits	102
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

ENAH_MOUSE
θ value	θ > 10 (rank : 349)	NC score	0.068860 (rank : 191)
Query Neighborhood Hits	296	Target Neighborhood Hits	919	Shared Neighborhood Hits	84
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

EP300_HUMAN
θ value	θ > 10 (rank : 350)	NC score	0.065044 (rank : 218)
Query Neighborhood Hits	296	Target Neighborhood Hits	821	Shared Neighborhood Hits	91
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

FA47A_HUMAN
θ value	θ > 10 (rank : 351)	NC score	0.110098 (rank : 56)
Query Neighborhood Hits	296	Target Neighborhood Hits	451	Shared Neighborhood Hits	93
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

FBX8_HUMAN
θ value	θ > 10 (rank : 352)	NC score	0.099110 (rank : 82)
Query Neighborhood Hits	296	Target Neighborhood Hits	44	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NRD0, Q6UWN4, Q9NRP5, Q9UKC4	Gene names	FBXO8, FBS, FBX8
Domain Architecture
Description	F-box only protein 8 (F-box/SEC7 protein FBS).

FBX8_MOUSE
θ value	θ > 10 (rank : 353)	NC score	0.099518 (rank : 80)
Query Neighborhood Hits	296	Target Neighborhood Hits	45	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QZN3	Gene names	Fbxo8, Fbx8
Domain Architecture
Description	F-box only protein 8.

FGD2_HUMAN
θ value	θ > 10 (rank : 354)	NC score	0.056541 (rank : 266)
Query Neighborhood Hits	296	Target Neighborhood Hits	151	Shared Neighborhood Hits	23
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

FGD2_MOUSE
θ value	θ > 10 (rank : 355)	NC score	0.058747 (rank : 252)
Query Neighborhood Hits	296	Target Neighborhood Hits	163	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

FGD3_HUMAN
θ value	θ > 10 (rank : 356)	NC score	0.051363 (rank : 323)
Query Neighborhood Hits	296	Target Neighborhood Hits	249	Shared Neighborhood Hits	19
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

FGD3_MOUSE
θ value	θ > 10 (rank : 357)	NC score	0.060831 (rank : 241)
Query Neighborhood Hits	296	Target Neighborhood Hits	257	Shared Neighborhood Hits	26
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

FGD5_HUMAN
θ value	θ > 10 (rank : 358)	NC score	0.068252 (rank : 197)
Query Neighborhood Hits	296	Target Neighborhood Hits	235	Shared Neighborhood Hits	28
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

FGD5_MOUSE
θ value	θ > 10 (rank : 359)	NC score	0.068244 (rank : 198)
Query Neighborhood Hits	296	Target Neighborhood Hits	170	Shared Neighborhood Hits	25
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

FGD6_MOUSE
θ value	θ > 10 (rank : 360)	NC score	0.077502 (rank : 150)
Query Neighborhood Hits	296	Target Neighborhood Hits	282	Shared Neighborhood Hits	45
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

FHOD1_HUMAN
θ value	θ > 10 (rank : 361)	NC score	0.056799 (rank : 263)
Query Neighborhood Hits	296	Target Neighborhood Hits	184	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y613, Q59F76, Q6Y1F2, Q76MS8, Q8N521	Gene names	FHOD1, FHOS
Domain Architecture
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

FMNL_HUMAN
θ value	θ > 10 (rank : 362)	NC score	0.083137 (rank : 124)
Query Neighborhood Hits	296	Target Neighborhood Hits	529	Shared Neighborhood Hits	64
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

FMNL_MOUSE
θ value	θ > 10 (rank : 363)	NC score	0.065626 (rank : 209)
Query Neighborhood Hits	296	Target Neighborhood Hits	428	Shared Neighborhood Hits	48
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

GA2L2_MOUSE
θ value	θ > 10 (rank : 364)	NC score	0.052864 (rank : 305)
Query Neighborhood Hits	296	Target Neighborhood Hits	395	Shared Neighborhood Hits	88
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

GAB1_HUMAN
θ value	θ > 10 (rank : 365)	NC score	0.076829 (rank : 156)
Query Neighborhood Hits	296	Target Neighborhood Hits	279	Shared Neighborhood Hits	70
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

GAB1_MOUSE
θ value	θ > 10 (rank : 366)	NC score	0.069528 (rank : 188)
Query Neighborhood Hits	296	Target Neighborhood Hits	233	Shared Neighborhood Hits	67
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

GAB2_HUMAN
θ value	θ > 10 (rank : 367)	NC score	0.057318 (rank : 260)
Query Neighborhood Hits	296	Target Neighborhood Hits	188	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UQC2, O60317	Gene names	GAB2, KIAA0571
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (pp100).

GAB2_MOUSE
θ value	θ > 10 (rank : 368)	NC score	0.062596 (rank : 233)
Query Neighborhood Hits	296	Target Neighborhood Hits	220	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

GBF1_HUMAN
θ value	θ > 10 (rank : 369)	NC score	0.111470 (rank : 55)
Query Neighborhood Hits	296	Target Neighborhood Hits	142	Shared Neighborhood Hits	19
SwissProt Accessions	Q92538, Q5VXX3, Q96CK6, Q96HZ3, Q9H473	Gene names	GBF1, KIAA0248
Domain Architecture
Description	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1).

GRAP_HUMAN
θ value	θ > 10 (rank : 370)	NC score	0.050831 (rank : 331)
Query Neighborhood Hits	296	Target Neighborhood Hits	307	Shared Neighborhood Hits	31
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

GRAP_MOUSE
θ value	θ > 10 (rank : 371)	NC score	0.051769 (rank : 318)
Query Neighborhood Hits	296	Target Neighborhood Hits	309	Shared Neighborhood Hits	31
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

GRB7_HUMAN
θ value	θ > 10 (rank : 372)	NC score	0.050539 (rank : 334)
Query Neighborhood Hits	296	Target Neighborhood Hits	156	Shared Neighborhood Hits	33
SwissProt Accessions	Q14451, Q92568, Q96DF9	Gene names	GRB7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7) (B47).

GSCR1_HUMAN
θ value	θ > 10 (rank : 373)	NC score	0.082184 (rank : 128)
Query Neighborhood Hits	296	Target Neighborhood Hits	674	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

HRX_HUMAN
θ value	θ > 10 (rank : 374)	NC score	0.054560 (rank : 285)
Query Neighborhood Hits	296	Target Neighborhood Hits	825	Shared Neighborhood Hits	56
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

IQEC1_HUMAN
θ value	θ > 10 (rank : 375)	NC score	0.095088 (rank : 97)
Query Neighborhood Hits	296	Target Neighborhood Hits	76	Shared Neighborhood Hits	15
SwissProt Accessions	Q6DN90, O94863, Q96D85	Gene names	IQSEC1, ARFGEP100, BRAG2, KIAA0763
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 1 (ADP-ribosylation factors guanine nucleotide-exchange protein 100) (ADP-ribosylation factors guanine nucleotide-exchange protein 2) (Brefeldin-resistant Arf-GEF 2 protein).

IQEC1_MOUSE
θ value	θ > 10 (rank : 376)	NC score	0.092735 (rank : 104)
Query Neighborhood Hits	296	Target Neighborhood Hits	54	Shared Neighborhood Hits	10
SwissProt Accessions	Q8R0S2, Q3TZC3, Q5DU15	Gene names	Iqsec1, Kiaa0763
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 1.

IQEC2_HUMAN
θ value	θ > 10 (rank : 377)	NC score	0.106611 (rank : 65)
Query Neighborhood Hits	296	Target Neighborhood Hits	403	Shared Neighborhood Hits	52
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IQEC2_MOUSE
θ value	θ > 10 (rank : 378)	NC score	0.106807 (rank : 63)
Query Neighborhood Hits	296	Target Neighborhood Hits	417	Shared Neighborhood Hits	51
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IQEC3_HUMAN
θ value	θ > 10 (rank : 379)	NC score	0.106322 (rank : 67)
Query Neighborhood Hits	296	Target Neighborhood Hits	125	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UPP2, Q8TB43	Gene names	IQSEC3, KIAA1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

IQEC3_MOUSE
θ value	θ > 10 (rank : 380)	NC score	0.112690 (rank : 53)
Query Neighborhood Hits	296	Target Neighborhood Hits	274	Shared Neighborhood Hits	46
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

IWS1_MOUSE
θ value	θ > 10 (rank : 381)	NC score	0.052995 (rank : 302)
Query Neighborhood Hits	296	Target Neighborhood Hits	1258	Shared Neighborhood Hits	97
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

K0310_HUMAN
θ value	θ > 10 (rank : 382)	NC score	0.055824 (rank : 270)
Query Neighborhood Hits	296	Target Neighborhood Hits	420	Shared Neighborhood Hits	74
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

K1543_HUMAN
θ value	θ > 10 (rank : 383)	NC score	0.051068 (rank : 330)
Query Neighborhood Hits	296	Target Neighborhood Hits	435	Shared Neighborhood Hits	72
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

K1543_MOUSE
θ value	θ > 10 (rank : 384)	NC score	0.055050 (rank : 281)
Query Neighborhood Hits	296	Target Neighborhood Hits	497	Shared Neighborhood Hits	75
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

K1802_HUMAN
θ value	θ > 10 (rank : 385)	NC score	0.065077 (rank : 217)
Query Neighborhood Hits	296	Target Neighborhood Hits	1378	Shared Neighborhood Hits	132
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

LCP2_MOUSE
θ value	θ > 10 (rank : 386)	NC score	0.076998 (rank : 153)
Query Neighborhood Hits	296	Target Neighborhood Hits	177	Shared Neighborhood Hits	34
SwissProt Accessions	Q60787	Gene names	Lcp2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

LNK_HUMAN
θ value	θ > 10 (rank : 387)	NC score	0.055398 (rank : 276)
Query Neighborhood Hits	296	Target Neighborhood Hits	151	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UQQ2, O95184	Gene names	LNK
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

LNK_MOUSE
θ value	θ > 10 (rank : 388)	NC score	0.055752 (rank : 272)
Query Neighborhood Hits	296	Target Neighborhood Hits	132	Shared Neighborhood Hits	19
SwissProt Accessions	O09039	Gene names	Lnk
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

LPP_HUMAN
θ value	θ > 10 (rank : 389)	NC score	0.056779 (rank : 264)
Query Neighborhood Hits	296	Target Neighborhood Hits	775	Shared Neighborhood Hits	123
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

MAGE1_HUMAN
θ value	θ > 10 (rank : 390)	NC score	0.074155 (rank : 165)
Query Neighborhood Hits	296	Target Neighborhood Hits	1389	Shared Neighborhood Hits	144
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MARCS_HUMAN
θ value	θ > 10 (rank : 391)	NC score	0.051423 (rank : 321)
Query Neighborhood Hits	296	Target Neighborhood Hits	204	Shared Neighborhood Hits	21
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

MBD6_HUMAN
θ value	θ > 10 (rank : 392)	NC score	0.083336 (rank : 123)
Query Neighborhood Hits	296	Target Neighborhood Hits	349	Shared Neighborhood Hits	52
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

MDC1_HUMAN
θ value	θ > 10 (rank : 393)	NC score	0.080672 (rank : 137)
Query Neighborhood Hits	296	Target Neighborhood Hits	1446	Shared Neighborhood Hits	125
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MDC1_MOUSE
θ value	θ > 10 (rank : 394)	NC score	0.082122 (rank : 129)
Query Neighborhood Hits	296	Target Neighborhood Hits	998	Shared Neighborhood Hits	120
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MILK1_MOUSE
θ value	θ > 10 (rank : 395)	NC score	0.066093 (rank : 206)
Query Neighborhood Hits	296	Target Neighborhood Hits	788	Shared Neighborhood Hits	121
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MINT_MOUSE
θ value	θ > 10 (rank : 396)	NC score	0.064991 (rank : 219)
Query Neighborhood Hits	296	Target Neighborhood Hits	1514	Shared Neighborhood Hits	142
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MISS_MOUSE
θ value	θ > 10 (rank : 397)	NC score	0.081364 (rank : 136)
Query Neighborhood Hits	296	Target Neighborhood Hits	444	Shared Neighborhood Hits	85
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

MKL1_MOUSE
θ value	θ > 10 (rank : 398)	NC score	0.050524 (rank : 335)
Query Neighborhood Hits	296	Target Neighborhood Hits	667	Shared Neighborhood Hits	104
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

MRIP_MOUSE
θ value	θ > 10 (rank : 399)	NC score	0.051210 (rank : 327)
Query Neighborhood Hits	296	Target Neighborhood Hits	569	Shared Neighborhood Hits	40
SwissProt Accessions	P97434, Q3TBR5, Q3TC85, Q3TRS0, Q3U1Y8, Q3U3E4, Q5SWZ3, Q5SWZ4, Q5SWZ7, Q6P559, Q80YC8	Gene names	Mrip, Kiaa0864, Rhoip3
Domain Architecture
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (p116Rip) (RIP3).

MUC1_MOUSE
θ value	θ > 10 (rank : 400)	NC score	0.055945 (rank : 269)
Query Neighborhood Hits	296	Target Neighborhood Hits	388	Shared Neighborhood Hits	32
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

MUC7_HUMAN
θ value	θ > 10 (rank : 401)	NC score	0.085405 (rank : 116)
Query Neighborhood Hits	296	Target Neighborhood Hits	538	Shared Neighborhood Hits	68
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

MUCDL_HUMAN
θ value	θ > 10 (rank : 402)	NC score	0.063220 (rank : 231)
Query Neighborhood Hits	296	Target Neighborhood Hits	777	Shared Neighborhood Hits	98
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

NACAM_MOUSE
θ value	θ > 10 (rank : 403)	NC score	0.103415 (rank : 71)
Query Neighborhood Hits	296	Target Neighborhood Hits	1866	Shared Neighborhood Hits	167
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NCK2_HUMAN
θ value	θ > 10 (rank : 404)	NC score	0.050016 (rank : 338)
Query Neighborhood Hits	296	Target Neighborhood Hits	310	Shared Neighborhood Hits	31
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

NOLC1_HUMAN
θ value	θ > 10 (rank : 405)	NC score	0.051975 (rank : 315)
Query Neighborhood Hits	296	Target Neighborhood Hits	452	Shared Neighborhood Hits	37
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

OGFR_HUMAN
θ value	θ > 10 (rank : 406)	NC score	0.102586 (rank : 74)
Query Neighborhood Hits	296	Target Neighborhood Hits	1582	Shared Neighborhood Hits	170
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

OSBP1_HUMAN
θ value	θ > 10 (rank : 407)	NC score	0.052774 (rank : 306)
Query Neighborhood Hits	296	Target Neighborhood Hits	180	Shared Neighborhood Hits	39
SwissProt Accessions	P22059	Gene names	OSBP, OSBP1
Domain Architecture
Description	Oxysterol-binding protein 1.

P85B_HUMAN
θ value	θ > 10 (rank : 408)	NC score	0.078237 (rank : 145)
Query Neighborhood Hits	296	Target Neighborhood Hits	543	Shared Neighborhood Hits	44
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

P85B_MOUSE
θ value	θ > 10 (rank : 409)	NC score	0.077244 (rank : 152)
Query Neighborhood Hits	296	Target Neighborhood Hits	519	Shared Neighborhood Hits	36
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

PCQAP_HUMAN
θ value	θ > 10 (rank : 410)	NC score	0.053180 (rank : 301)
Query Neighborhood Hits	296	Target Neighborhood Hits	549	Shared Neighborhood Hits	49
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

PELP1_MOUSE
θ value	θ > 10 (rank : 411)	NC score	0.071095 (rank : 180)
Query Neighborhood Hits	296	Target Neighborhood Hits	709	Shared Neighborhood Hits	92
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

PHLB1_HUMAN
θ value	θ > 10 (rank : 412)	NC score	0.072657 (rank : 169)
Query Neighborhood Hits	296	Target Neighborhood Hits	1038	Shared Neighborhood Hits	111
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PHLB1_MOUSE
θ value	θ > 10 (rank : 413)	NC score	0.071725 (rank : 175)
Query Neighborhood Hits	296	Target Neighborhood Hits	678	Shared Neighborhood Hits	80
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PI5PA_HUMAN
θ value	θ > 10 (rank : 414)	NC score	0.071733 (rank : 174)
Query Neighborhood Hits	296	Target Neighborhood Hits	749	Shared Neighborhood Hits	121
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PKHB1_HUMAN
θ value	θ > 10 (rank : 415)	NC score	0.061193 (rank : 238)
Query Neighborhood Hits	296	Target Neighborhood Hits	46	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UF11, Q9UBF5, Q9UI37, Q9UI44	Gene names	PLEKHB1, KPL1, PHR1
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 1 (Pleckstrin homology domain retinal protein 1) (PH domain-containing protein in retina 1) (PHRET1).

PKHB1_MOUSE
θ value	θ > 10 (rank : 416)	NC score	0.054202 (rank : 289)
Query Neighborhood Hits	296	Target Neighborhood Hits	47	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QYE9, Q9QYB3, Q9QYB4, Q9QYD2, Q9QYD3	Gene names	Plekhb1, Phr1
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 1 (Pleckstrin homology domain retinal protein 1) (PH domain-containing protein in retina 1) (PHRET1).

PKHB2_HUMAN
θ value	θ > 10 (rank : 417)	NC score	0.076084 (rank : 160)
Query Neighborhood Hits	296	Target Neighborhood Hits	54	Shared Neighborhood Hits	23
SwissProt Accessions	Q96CS7, Q86W37, Q9BV75, Q9NWK1	Gene names	PLEKHB2, EVT2
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 2 (Evectin-2).

PKHB2_MOUSE
θ value	θ > 10 (rank : 418)	NC score	0.083897 (rank : 121)
Query Neighborhood Hits	296	Target Neighborhood Hits	48	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QZC7, Q3UDH6, Q8C4I4, Q8CA27	Gene names	Plekhb2, Evt2
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 2 (Evectin-2).

PLCG1_HUMAN
θ value	θ > 10 (rank : 419)	NC score	0.051243 (rank : 326)
Query Neighborhood Hits	296	Target Neighborhood Hits	293	Shared Neighborhood Hits	33
SwissProt Accessions	P19174, Q2V575	Gene names	PLCG1, PLC1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

PLCG1_MOUSE
θ value	θ > 10 (rank : 420)	NC score	0.050752 (rank : 332)
Query Neighborhood Hits	296	Target Neighborhood Hits	314	Shared Neighborhood Hits	33
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

PRB3_HUMAN
θ value	θ > 10 (rank : 421)	NC score	0.070104 (rank : 186)
Query Neighborhood Hits	296	Target Neighborhood Hits	318	Shared Neighborhood Hits	43
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

PRB4S_HUMAN
θ value	θ > 10 (rank : 422)	NC score	0.081979 (rank : 132)
Query Neighborhood Hits	296	Target Neighborhood Hits	330	Shared Neighborhood Hits	52
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

PRG4_MOUSE
θ value	θ > 10 (rank : 423)	NC score	0.063988 (rank : 227)
Query Neighborhood Hits	296	Target Neighborhood Hits	624	Shared Neighborhood Hits	58
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRGC2_MOUSE
θ value	θ > 10 (rank : 424)	NC score	0.057228 (rank : 261)
Query Neighborhood Hits	296	Target Neighborhood Hits	225	Shared Neighborhood Hits	22
SwissProt Accessions	Q8VHJ7, Q8C1C0	Gene names	Ppargc1b, Errl1, Pgc1, Pgc1b, Ppargc1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta protein) (PGC-1beta) (ERR ligand 1) (PPARGC-1-beta) (PGC-1-beta).

PRP1_HUMAN
θ value	θ > 10 (rank : 425)	NC score	0.098854 (rank : 87)
Query Neighborhood Hits	296	Target Neighborhood Hits	385	Shared Neighborhood Hits	51
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PSD3_HUMAN
θ value	θ > 10 (rank : 426)	NC score	0.124116 (rank : 42)
Query Neighborhood Hits	296	Target Neighborhood Hits	75	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NYI0, Q9Y2F1	Gene names	PSD3, EFA6R, HCA67, KIAA0942
Domain Architecture
Description	PH and SEC7 domain-containing protein 3 (Pleckstrin homology and SEC7 domain-containing protein 3) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6) (Hepatocellular carcinoma- associated antigen 67).

PSD4_HUMAN
θ value	θ > 10 (rank : 427)	NC score	0.113950 (rank : 52)
Query Neighborhood Hits	296	Target Neighborhood Hits	178	Shared Neighborhood Hits	32
SwissProt Accessions	Q8NDX1, O95621, Q4ZG34, Q6GPH8, Q8IYP4	Gene names	PSD4, EFA6B, TIC
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B) (Telomeric of interleukin-1 cluster protein).

PSD4_MOUSE
θ value	θ > 10 (rank : 428)	NC score	0.102625 (rank : 73)
Query Neighborhood Hits	296	Target Neighborhood Hits	78	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BLR5, Q3TE33, Q3TQF5, Q3UD59, Q3UFH9, Q80V44	Gene names	Psd4
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4).

PSL1_HUMAN
θ value	θ > 10 (rank : 429)	NC score	0.071193 (rank : 179)
Query Neighborhood Hits	296	Target Neighborhood Hits	650	Shared Neighborhood Hits	126
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

RASA3_HUMAN
θ value	θ > 10 (rank : 430)	NC score	0.053681 (rank : 293)
Query Neighborhood Hits	296	Target Neighborhood Hits	166	Shared Neighborhood Hits	34
SwissProt Accessions	Q14644	Gene names	RASA3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein).

RGS3_MOUSE
θ value	θ > 10 (rank : 431)	NC score	0.106460 (rank : 66)
Query Neighborhood Hits	296	Target Neighborhood Hits	1621	Shared Neighborhood Hits	176
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SC24C_HUMAN
θ value	θ > 10 (rank : 432)	NC score	0.076190 (rank : 159)
Query Neighborhood Hits	296	Target Neighborhood Hits	662	Shared Neighborhood Hits	111
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

SELPL_MOUSE
θ value	θ > 10 (rank : 433)	NC score	0.068677 (rank : 193)
Query Neighborhood Hits	296	Target Neighborhood Hits	588	Shared Neighborhood Hits	90
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SELV_HUMAN
θ value	θ > 10 (rank : 434)	NC score	0.056136 (rank : 268)
Query Neighborhood Hits	296	Target Neighborhood Hits	118	Shared Neighborhood Hits	22
SwissProt Accessions	P59797	Gene names	SELV
Domain Architecture	No domain graphic available
Description	Selenoprotein V.

SF3A2_HUMAN
θ value	θ > 10 (rank : 435)	NC score	0.069304 (rank : 190)
Query Neighborhood Hits	296	Target Neighborhood Hits	263	Shared Neighborhood Hits	41
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SF3A2_MOUSE
θ value	θ > 10 (rank : 436)	NC score	0.064835 (rank : 223)
Query Neighborhood Hits	296	Target Neighborhood Hits	247	Shared Neighborhood Hits	41
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SFPQ_MOUSE
θ value	θ > 10 (rank : 437)	NC score	0.058683 (rank : 253)
Query Neighborhood Hits	296	Target Neighborhood Hits	958	Shared Neighborhood Hits	73
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

SH21B_HUMAN
θ value	θ > 10 (rank : 438)	NC score	0.051134 (rank : 328)
Query Neighborhood Hits	296	Target Neighborhood Hits	101	Shared Neighborhood Hits	14
SwissProt Accessions	O14796, Q5T0L1, Q8NI18, Q969K9	Gene names	SH2D1B, EAT2
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

SH21B_MOUSE
θ value	θ > 10 (rank : 439)	NC score	0.052924 (rank : 303)
Query Neighborhood Hits	296	Target Neighborhood Hits	101	Shared Neighborhood Hits	15
SwissProt Accessions	O35324, Q8C268	Gene names	Sh2d1b, Eat2, Sh2d1b1
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

SLAP2_HUMAN
θ value	θ > 10 (rank : 440)	NC score	0.052634 (rank : 308)
Query Neighborhood Hits	296	Target Neighborhood Hits	139	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H6Q3, Q5TH27, Q5TH28, Q8WY18, Q96QI4, Q9H135	Gene names	SLA2, C20orf156, SLAP2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2) (Modulator of antigen receptor signaling) (MARS).

SNPC4_HUMAN
θ value	θ > 10 (rank : 441)	NC score	0.065217 (rank : 216)
Query Neighborhood Hits	296	Target Neighborhood Hits	589	Shared Neighborhood Hits	92
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

SON_MOUSE
θ value	θ > 10 (rank : 442)	NC score	0.082031 (rank : 131)
Query Neighborhood Hits	296	Target Neighborhood Hits	957	Shared Neighborhood Hits	116
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

SPR1A_MOUSE
θ value	θ > 10 (rank : 443)	NC score	0.070311 (rank : 185)
Query Neighborhood Hits	296	Target Neighborhood Hits	343	Shared Neighborhood Hits	88
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

SPR1B_MOUSE
θ value	θ > 10 (rank : 444)	NC score	0.082663 (rank : 127)
Query Neighborhood Hits	296	Target Neighborhood Hits	395	Shared Neighborhood Hits	96
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

SRRM2_HUMAN
θ value	θ > 10 (rank : 445)	NC score	0.063323 (rank : 228)
Query Neighborhood Hits	296	Target Neighborhood Hits	1296	Shared Neighborhood Hits	95
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SRRM2_MOUSE
θ value	θ > 10 (rank : 446)	NC score	0.063296 (rank : 229)
Query Neighborhood Hits	296	Target Neighborhood Hits	1470	Shared Neighborhood Hits	106
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

SWP70_HUMAN
θ value	θ > 10 (rank : 447)	NC score	0.075674 (rank : 161)
Query Neighborhood Hits	296	Target Neighborhood Hits	973	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SWP70_MOUSE
θ value	θ > 10 (rank : 448)	NC score	0.073525 (rank : 167)
Query Neighborhood Hits	296	Target Neighborhood Hits	1097	Shared Neighborhood Hits	60
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SYN1_MOUSE
θ value	θ > 10 (rank : 449)	NC score	0.050348 (rank : 336)
Query Neighborhood Hits	296	Target Neighborhood Hits	363	Shared Neighborhood Hits	49
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

TAF4_HUMAN
θ value	θ > 10 (rank : 450)	NC score	0.078034 (rank : 147)
Query Neighborhood Hits	296	Target Neighborhood Hits	687	Shared Neighborhood Hits	71
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

TARA_HUMAN
θ value	θ > 10 (rank : 451)	NC score	0.068838 (rank : 192)
Query Neighborhood Hits	296	Target Neighborhood Hits	1626	Shared Neighborhood Hits	123
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TARA_MOUSE
θ value	θ > 10 (rank : 452)	NC score	0.067938 (rank : 200)
Query Neighborhood Hits	296	Target Neighborhood Hits	1133	Shared Neighborhood Hits	94
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TARSH_HUMAN
θ value	θ > 10 (rank : 453)	NC score	0.111816 (rank : 54)
Query Neighborhood Hits	296	Target Neighborhood Hits	768	Shared Neighborhood Hits	120
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

TGON2_HUMAN
θ value	θ > 10 (rank : 454)	NC score	0.053311 (rank : 298)
Query Neighborhood Hits	296	Target Neighborhood Hits	1037	Shared Neighborhood Hits	80
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TXND2_HUMAN
θ value	θ > 10 (rank : 455)	NC score	0.061392 (rank : 237)
Query Neighborhood Hits	296	Target Neighborhood Hits	793	Shared Neighborhood Hits	75
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

VAV3_HUMAN
θ value	θ > 10 (rank : 456)	NC score	0.052299 (rank : 312)
Query Neighborhood Hits	296	Target Neighborhood Hits	398	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

VAV3_MOUSE
θ value	θ > 10 (rank : 457)	NC score	0.054490 (rank : 287)
Query Neighborhood Hits	296	Target Neighborhood Hits	404	Shared Neighborhood Hits	39
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

WASF2_HUMAN
θ value	θ > 10 (rank : 458)	NC score	0.060274 (rank : 247)
Query Neighborhood Hits	296	Target Neighborhood Hits	280	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

WASF3_HUMAN
θ value	θ > 10 (rank : 459)	NC score	0.051874 (rank : 316)
Query Neighborhood Hits	296	Target Neighborhood Hits	204	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UPY6, O94974	Gene names	WASF3, KIAA0900, SCAR3, WAVE3
Domain Architecture
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3) (Verprolin homology domain-containing protein 3).

WASF4_HUMAN
θ value	θ > 10 (rank : 460)	NC score	0.066444 (rank : 203)
Query Neighborhood Hits	296	Target Neighborhood Hits	282	Shared Neighborhood Hits	57
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

WASIP_MOUSE
θ value	θ > 10 (rank : 461)	NC score	0.094629 (rank : 98)
Query Neighborhood Hits	296	Target Neighborhood Hits	392	Shared Neighborhood Hits	68
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

WASL_HUMAN
θ value	θ > 10 (rank : 462)	NC score	0.073468 (rank : 168)
Query Neighborhood Hits	296	Target Neighborhood Hits	312	Shared Neighborhood Hits	60
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WASP_HUMAN
θ value	θ > 10 (rank : 463)	NC score	0.054565 (rank : 284)
Query Neighborhood Hits	296	Target Neighborhood Hits	195	Shared Neighborhood Hits	34
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

WIRE_HUMAN
θ value	θ > 10 (rank : 464)	NC score	0.068647 (rank : 194)
Query Neighborhood Hits	296	Target Neighborhood Hits	329	Shared Neighborhood Hits	49
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

WIRE_MOUSE
θ value	θ > 10 (rank : 465)	NC score	0.065444 (rank : 213)
Query Neighborhood Hits	296	Target Neighborhood Hits	310	Shared Neighborhood Hits	54
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

ZIMP7_MOUSE
θ value	θ > 10 (rank : 466)	NC score	0.050295 (rank : 337)
Query Neighborhood Hits	296	Target Neighborhood Hits	566	Shared Neighborhood Hits	96
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

ZN385_HUMAN
θ value	θ > 10 (rank : 467)	NC score	0.055683 (rank : 273)
Query Neighborhood Hits	296	Target Neighborhood Hits	614	Shared Neighborhood Hits	93
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

Hits sorted by NC score

3BP2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	296	Target Neighborhood Hits	296	Shared Neighborhood Hits	296
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

3BP2_MOUSE
NC score	0.925478 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	296	Target Neighborhood Hits	142	Shared Neighborhood Hits	90
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

PKHA6_MOUSE
NC score	0.343618 (rank : 3)	θ value	2.21117e-06 (rank : 3)
Query Neighborhood Hits	296	Target Neighborhood Hits	591	Shared Neighborhood Hits	89
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA6_HUMAN
NC score	0.338320 (rank : 4)	θ value	2.88788e-06 (rank : 4)
Query Neighborhood Hits	296	Target Neighborhood Hits	556	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA4_HUMAN
NC score	0.311410 (rank : 5)	θ value	0.000786445 (rank : 14)
Query Neighborhood Hits	296	Target Neighborhood Hits	283	Shared Neighborhood Hits	69
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PKHA4_MOUSE
NC score	0.308497 (rank : 6)	θ value	0.00228821 (rank : 19)
Query Neighborhood Hits	296	Target Neighborhood Hits	202	Shared Neighborhood Hits	50
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PLEK_HUMAN
NC score	0.286813 (rank : 7)	θ value	0.00509761 (rank : 28)
Query Neighborhood Hits	296	Target Neighborhood Hits	110	Shared Neighborhood Hits	43
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

PLEK2_MOUSE
NC score	0.275981 (rank : 8)	θ value	0.00298849 (rank : 22)
Query Neighborhood Hits	296	Target Neighborhood Hits	96	Shared Neighborhood Hits	33
SwissProt Accessions	Q9WV52	Gene names	Plek2
Domain Architecture
Description	Pleckstrin-2.

PKHA1_HUMAN
NC score	0.275178 (rank : 9)	θ value	0.00390308 (rank : 26)
Query Neighborhood Hits	296	Target Neighborhood Hits	127	Shared Neighborhood Hits	41
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA1_MOUSE
NC score	0.273804 (rank : 10)	θ value	0.00390308 (rank : 27)
Query Neighborhood Hits	296	Target Neighborhood Hits	120	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PLEK_MOUSE
NC score	0.273434 (rank : 11)	θ value	0.0252991 (rank : 37)
Query Neighborhood Hits	296	Target Neighborhood Hits	109	Shared Neighborhood Hits	40
SwissProt Accessions	Q9JHK5, Q9ERI9	Gene names	Plek
Domain Architecture
Description	Pleckstrin.

CYH3_HUMAN
NC score	0.271813 (rank : 12)	θ value	0.00035302 (rank : 6)
Query Neighborhood Hits	296	Target Neighborhood Hits	137	Shared Neighborhood Hits	45
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

CYH3_MOUSE
NC score	0.271236 (rank : 13)	θ value	0.000602161 (rank : 9)
Query Neighborhood Hits	296	Target Neighborhood Hits	148	Shared Neighborhood Hits	45
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

PLEK2_HUMAN
NC score	0.270976 (rank : 14)	θ value	0.00665767 (rank : 30)
Query Neighborhood Hits	296	Target Neighborhood Hits	101	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

CYH1_HUMAN
NC score	0.269913 (rank : 15)	θ value	0.000786445 (rank : 11)
Query Neighborhood Hits	296	Target Neighborhood Hits	184	Shared Neighborhood Hits	48
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

CYH1_MOUSE
NC score	0.268628 (rank : 16)	θ value	0.000786445 (rank : 12)
Query Neighborhood Hits	296	Target Neighborhood Hits	176	Shared Neighborhood Hits	47
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

CYH4_HUMAN
NC score	0.268114 (rank : 17)	θ value	0.00102713 (rank : 16)
Query Neighborhood Hits	296	Target Neighborhood Hits	135	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UIA0, Q5R3F9, Q9UGT6	Gene names	PSCD4, CYT4
Domain Architecture
Description	Cytohesin-4.

CYH4_MOUSE
NC score	0.268063 (rank : 18)	θ value	0.000786445 (rank : 13)
Query Neighborhood Hits	296	Target Neighborhood Hits	134	Shared Neighborhood Hits	45
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

PKHA5_HUMAN
NC score	0.264823 (rank : 19)	θ value	0.000786445 (rank : 15)
Query Neighborhood Hits	296	Target Neighborhood Hits	455	Shared Neighborhood Hits	48
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

CYH2_HUMAN
NC score	0.263178 (rank : 20)	θ value	0.00298849 (rank : 20)
Query Neighborhood Hits	296	Target Neighborhood Hits	175	Shared Neighborhood Hits	45
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

CYH2_MOUSE
NC score	0.263076 (rank : 21)	θ value	0.00298849 (rank : 21)
Query Neighborhood Hits	296	Target Neighborhood Hits	171	Shared Neighborhood Hits	45
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

DAPP1_MOUSE
NC score	0.246640 (rank : 22)	θ value	0.00228821 (rank : 18)
Query Neighborhood Hits	296	Target Neighborhood Hits	225	Shared Neighborhood Hits	53
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DAPP1_HUMAN
NC score	0.245233 (rank : 23)	θ value	0.00390308 (rank : 23)
Query Neighborhood Hits	296	Target Neighborhood Hits	227	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

RHG25_MOUSE
NC score	0.211178 (rank : 24)	θ value	0.00020696 (rank : 5)
Query Neighborhood Hits	296	Target Neighborhood Hits	492	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

PKHA2_MOUSE
NC score	0.207291 (rank : 25)	θ value	3.0926 (rank : 180)
Query Neighborhood Hits	296	Target Neighborhood Hits	116	Shared Neighborhood Hits	39
SwissProt Accessions	Q9ERS5, Q8BY29	Gene names	Plekha2, Tapp2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2) (PH domain-containing adaptor PHAD47).

PKHA2_HUMAN
NC score	0.205163 (rank : 26)	θ value	1.81305 (rank : 148)
Query Neighborhood Hits	296	Target Neighborhood Hits	119	Shared Neighborhood Hits	42
SwissProt Accessions	Q9HB19	Gene names	PLEKHA2, TAPP2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2).

RHG25_HUMAN
NC score	0.202035 (rank : 27)	θ value	0.00102713 (rank : 17)
Query Neighborhood Hits	296	Target Neighborhood Hits	550	Shared Neighborhood Hits	55
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

PRRT3_HUMAN
NC score	0.175135 (rank : 28)	θ value	0.00509761 (rank : 29)
Query Neighborhood Hits	296	Target Neighborhood Hits	998	Shared Neighborhood Hits	156
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

RASA1_HUMAN
NC score	0.160291 (rank : 29)	θ value	0.0252991 (rank : 38)
Query Neighborhood Hits	296	Target Neighborhood Hits	258	Shared Neighborhood Hits	50
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

FA47B_HUMAN
NC score	0.153468 (rank : 30)	θ value	0.0252991 (rank : 36)
Query Neighborhood Hits	296	Target Neighborhood Hits	431	Shared Neighborhood Hits	105
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

LCP2_HUMAN
NC score	0.145629 (rank : 31)	θ value	0.0193708 (rank : 34)
Query Neighborhood Hits	296	Target Neighborhood Hits	531	Shared Neighborhood Hits	108
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

CNKR1_HUMAN
NC score	0.143426 (rank : 32)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	296	Target Neighborhood Hits	154	Shared Neighborhood Hits	36
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

PRGC2_HUMAN
NC score	0.135006 (rank : 33)	θ value	0.00035302 (rank : 7)
Query Neighborhood Hits	296	Target Neighborhood Hits	272	Shared Neighborhood Hits	41
SwissProt Accessions	Q86YN6, Q86YN3, Q86YN4, Q86YN5, Q8N1N9, Q8TDE4, Q8TDE5	Gene names	PPARGC1B, PERC, PGC1, PGC1B, PPARGC1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta) (PGC-1-related estrogen receptor alpha coactivator) (PPARGC-1-beta) (PGC-1-beta).

MUC1_HUMAN
NC score	0.131374 (rank : 34)	θ value	0.00390308 (rank : 24)
Query Neighborhood Hits	296	Target Neighborhood Hits	975	Shared Neighborhood Hits	136
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

FMN2_MOUSE
NC score	0.127429 (rank : 35)	θ value	0.0961366 (rank : 50)
Query Neighborhood Hits	296	Target Neighborhood Hits	349	Shared Neighborhood Hits	68
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

BLNK_HUMAN
NC score	0.126467 (rank : 36)	θ value	0.62314 (rank : 81)
Query Neighborhood Hits	296	Target Neighborhood Hits	228	Shared Neighborhood Hits	54
SwissProt Accessions	Q8WV28, O75498, O75499	Gene names	BLNK, BASH, SLP65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (SLP-65).

APS_HUMAN
NC score	0.126419 (rank : 37)	θ value	0.21417 (rank : 62)
Query Neighborhood Hits	296	Target Neighborhood Hits	162	Shared Neighborhood Hits	26
SwissProt Accessions	O14492	Gene names	APS
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

SAPS1_HUMAN
NC score	0.126188 (rank : 38)	θ value	0.000602161 (rank : 10)
Query Neighborhood Hits	296	Target Neighborhood Hits	704	Shared Neighborhood Hits	110
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

PRR12_HUMAN
NC score	0.125237 (rank : 39)	θ value	0.365318 (rank : 73)
Query Neighborhood Hits	296	Target Neighborhood Hits	460	Shared Neighborhood Hits	64
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

GNRP_HUMAN
NC score	0.124888 (rank : 40)	θ value	0.21417 (rank : 64)
Query Neighborhood Hits	296	Target Neighborhood Hits	239	Shared Neighborhood Hits	39
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

FMN2_HUMAN
NC score	0.124556 (rank : 41)	θ value	1.81305 (rank : 142)
Query Neighborhood Hits	296	Target Neighborhood Hits	484	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

PSD3_HUMAN
NC score	0.124116 (rank : 42)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	296	Target Neighborhood Hits	75	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NYI0, Q9Y2F1	Gene names	PSD3, EFA6R, HCA67, KIAA0942
Domain Architecture
Description	PH and SEC7 domain-containing protein 3 (Pleckstrin homology and SEC7 domain-containing protein 3) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6) (Hepatocellular carcinoma- associated antigen 67).

MLL3_HUMAN
NC score	0.123638 (rank : 43)	θ value	1.06291 (rank : 107)
Query Neighborhood Hits	296	Target Neighborhood Hits	1644	Shared Neighborhood Hits	161
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

FMN1B_MOUSE
NC score	0.123422 (rank : 44)	θ value	0.163984 (rank : 60)
Query Neighborhood Hits	296	Target Neighborhood Hits	447	Shared Neighborhood Hits	67
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

NCOA6_HUMAN
NC score	0.121677 (rank : 45)	θ value	1.38821 (rank : 126)
Query Neighborhood Hits	296	Target Neighborhood Hits	1202	Shared Neighborhood Hits	146
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

FMN1A_MOUSE
NC score	0.121570 (rank : 46)	θ value	0.163984 (rank : 59)
Query Neighborhood Hits	296	Target Neighborhood Hits	423	Shared Neighborhood Hits	63
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

APS_MOUSE
NC score	0.121268 (rank : 47)	θ value	0.0961366 (rank : 49)
Query Neighborhood Hits	296	Target Neighborhood Hits	134	Shared Neighborhood Hits	19
SwissProt Accessions	Q9JID9, O88936	Gene names	Aps
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

SON_HUMAN
NC score	0.120659 (rank : 48)	θ value	0.813845 (rank : 99)
Query Neighborhood Hits	296	Target Neighborhood Hits	1568	Shared Neighborhood Hits	181
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

BLNK_MOUSE
NC score	0.118778 (rank : 49)	θ value	1.06291 (rank : 103)
Query Neighborhood Hits	296	Target Neighborhood Hits	296	Shared Neighborhood Hits	67
SwissProt Accessions	Q9QUN3, O88504	Gene names	Blnk, Bash, Ly57, Slp65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65) (Lymphocyte antigen 57).

YLPM1_MOUSE
NC score	0.117314 (rank : 50)	θ value	0.21417 (rank : 66)
Query Neighborhood Hits	296	Target Neighborhood Hits	505	Shared Neighborhood Hits	69
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

GNRP_MOUSE
NC score	0.116515 (rank : 51)	θ value	1.38821 (rank : 120)
Query Neighborhood Hits	296	Target Neighborhood Hits	191	Shared Neighborhood Hits	44
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

PSD4_HUMAN
NC score	0.113950 (rank : 52)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	296	Target Neighborhood Hits	178	Shared Neighborhood Hits	32
SwissProt Accessions	Q8NDX1, O95621, Q4ZG34, Q6GPH8, Q8IYP4	Gene names	PSD4, EFA6B, TIC
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B) (Telomeric of interleukin-1 cluster protein).

IQEC3_MOUSE
NC score	0.112690 (rank : 53)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	296	Target Neighborhood Hits	274	Shared Neighborhood Hits	46
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

TARSH_HUMAN
NC score	0.111816 (rank : 54)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	296	Target Neighborhood Hits	768	Shared Neighborhood Hits	120
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

GBF1_HUMAN
NC score	0.111470 (rank : 55)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	296	Target Neighborhood Hits	142	Shared Neighborhood Hits	19
SwissProt Accessions	Q92538, Q5VXX3, Q96CK6, Q96HZ3, Q9H473	Gene names	GBF1, KIAA0248
Domain Architecture
Description	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1).

FA47A_HUMAN
NC score	0.110098 (rank : 56)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	296	Target Neighborhood Hits	451	Shared Neighborhood Hits	93
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

WASIP_HUMAN
NC score	0.110022 (rank : 57)	θ value	3.0926 (rank : 189)
Query Neighborhood Hits	296	Target Neighborhood Hits	458	Shared Neighborhood Hits	68
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

BAT2_HUMAN
NC score	0.109460 (rank : 58)	θ value	1.81305 (rank : 137)
Query Neighborhood Hits	296	Target Neighborhood Hits	931	Shared Neighborhood Hits	117
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

SET1A_HUMAN
NC score	0.109331 (rank : 59)	θ value	0.0113563 (rank : 33)
Query Neighborhood Hits	296	Target Neighborhood Hits	690	Shared Neighborhood Hits	66
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

MLL3_MOUSE
NC score	0.108769 (rank : 60)	θ value	0.0330416 (rank : 41)
Query Neighborhood Hits	296	Target Neighborhood Hits	1399	Shared Neighborhood Hits	137
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

BIG2_HUMAN
NC score	0.107587 (rank : 61)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	296	Target Neighborhood Hits	66	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y6D5, Q5TFT9, Q9NTS1	Gene names	ARFGEF2, ARFGEP2, BIG2
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (Brefeldin A-inhibited GEP 2).

BIG1_HUMAN
NC score	0.107241 (rank : 62)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	296	Target Neighborhood Hits	76	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y6D6, Q9NV46, Q9UFV2, Q9UNL0	Gene names	ARFGEF1, ARFGEP1, BIG1
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Brefeldin A-inhibited GEP 1) (p200 ARF-GEP1) (p200 ARF guanine nucleotide exchange factor).

IQEC2_MOUSE
NC score	0.106807 (rank : 63)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	296	Target Neighborhood Hits	417	Shared Neighborhood Hits	51
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

WBP11_HUMAN
NC score	0.106616 (rank : 64)	θ value	0.47712 (rank : 79)
Query Neighborhood Hits	296	Target Neighborhood Hits	354	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

IQEC2_HUMAN
NC score	0.106611 (rank : 65)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	296	Target Neighborhood Hits	403	Shared Neighborhood Hits	52
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

RGS3_MOUSE
NC score	0.106460 (rank : 66)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	296	Target Neighborhood Hits	1621	Shared Neighborhood Hits	176
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

IQEC3_HUMAN
NC score	0.106322 (rank : 67)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	296	Target Neighborhood Hits	125	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UPP2, Q8TB43	Gene names	IQSEC3, KIAA1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

WBP11_MOUSE
NC score	0.106072 (rank : 68)	θ value	0.47712 (rank : 80)
Query Neighborhood Hits	296	Target Neighborhood Hits	362	Shared Neighborhood Hits	50
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

CNKR2_MOUSE
NC score	0.105218 (rank : 69)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	296	Target Neighborhood Hits	197	Shared Neighborhood Hits	35
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_HUMAN
NC score	0.105074 (rank : 70)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	296	Target Neighborhood Hits	197	Shared Neighborhood Hits	35
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

NACAM_MOUSE
NC score	0.103415 (rank : 71)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	296	Target Neighborhood Hits	1866	Shared Neighborhood Hits	167
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PRP2_MOUSE
NC score	0.103080 (rank : 72)	θ value	6.88961 (rank : 257)
Query Neighborhood Hits	296	Target Neighborhood Hits	347	Shared Neighborhood Hits	51
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PSD4_MOUSE
NC score	0.102625 (rank : 73)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	296	Target Neighborhood Hits	78	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BLR5, Q3TE33, Q3TQF5, Q3UD59, Q3UFH9, Q80V44	Gene names	Psd4
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4).

OGFR_HUMAN
NC score	0.102586 (rank : 74)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	296	Target Neighborhood Hits	1582	Shared Neighborhood Hits	170
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

FARP1_HUMAN
NC score	0.102037 (rank : 75)	θ value	0.0563607 (rank : 45)
Query Neighborhood Hits	296	Target Neighborhood Hits	241	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

BCL9_HUMAN
NC score	0.101019 (rank : 76)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	296	Target Neighborhood Hits	1008	Shared Neighborhood Hits	151
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

MLL2_HUMAN
NC score	0.101014 (rank : 77)	θ value	1.38821 (rank : 125)
Query Neighborhood Hits	296	Target Neighborhood Hits	1788	Shared Neighborhood Hits	136
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

FARP2_MOUSE
NC score	0.100647 (rank : 78)	θ value	0.21417 (rank : 63)
Query Neighborhood Hits	296	Target Neighborhood Hits	209	Shared Neighborhood Hits	40
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

NCOA6_MOUSE
NC score	0.099807 (rank : 79)	θ value	1.38821 (rank : 127)
Query Neighborhood Hits	296	Target Neighborhood Hits	1076	Shared Neighborhood Hits	122
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

FBX8_MOUSE
NC score	0.099518 (rank : 80)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	296	Target Neighborhood Hits	45	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QZN3	Gene names	Fbxo8, Fbx8
Domain Architecture
Description	F-box only protein 8.

FGD1_MOUSE
NC score	0.099221 (rank : 81)	θ value	0.47712 (rank : 76)
Query Neighborhood Hits	296	Target Neighborhood Hits	387	Shared Neighborhood Hits	67
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FBX8_HUMAN
NC score	0.099110 (rank : 82)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	296	Target Neighborhood Hits	44	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NRD0, Q6UWN4, Q9NRP5, Q9UKC4	Gene names	FBXO8, FBS, FBX8
Domain Architecture
Description	F-box only protein 8 (F-box/SEC7 protein FBS).

P85A_HUMAN
NC score	0.098933 (rank : 83)	θ value	1.06291 (rank : 108)
Query Neighborhood Hits	296	Target Neighborhood Hits	479	Shared Neighborhood Hits	36
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

MLL4_HUMAN
NC score	0.098929 (rank : 84)	θ value	0.813845 (rank : 93)
Query Neighborhood Hits	296	Target Neighborhood Hits	722	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

GGN_HUMAN
NC score	0.098920 (rank : 85)	θ value	5.27518 (rank : 221)
Query Neighborhood Hits	296	Target Neighborhood Hits	269	Shared Neighborhood Hits	50
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GGN_MOUSE
NC score	0.098864 (rank : 86)	θ value	1.81305 (rank : 143)
Query Neighborhood Hits	296	Target Neighborhood Hits	311	Shared Neighborhood Hits	58
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

PRP1_HUMAN
NC score	0.098854 (rank : 87)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	296	Target Neighborhood Hits	385	Shared Neighborhood Hits	51
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

RAPH1_HUMAN
NC score	0.098712 (rank : 88)	θ value	3.0926 (rank : 181)
Query Neighborhood Hits	296	Target Neighborhood Hits	593	Shared Neighborhood Hits	92
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

CEND2_HUMAN
NC score	0.098682 (rank : 89)	θ value	0.62314 (rank : 82)
Query Neighborhood Hits	296	Target Neighborhood Hits	166	Shared Neighborhood Hits	45
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

BAT2_MOUSE
NC score	0.097896 (rank : 90)	θ value	3.0926 (rank : 167)
Query Neighborhood Hits	296	Target Neighborhood Hits	947	Shared Neighborhood Hits	121
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

P55G_MOUSE
NC score	0.097865 (rank : 91)	θ value	0.21417 (rank : 65)
Query Neighborhood Hits	296	Target Neighborhood Hits	401	Shared Neighborhood Hits	25
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

SRRM1_MOUSE
NC score	0.097853 (rank : 92)	θ value	8.99809 (rank : 293)
Query Neighborhood Hits	296	Target Neighborhood Hits	966	Shared Neighborhood Hits	106
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

P85A_MOUSE
NC score	0.096423 (rank : 93)	θ value	1.38821 (rank : 128)
Query Neighborhood Hits	296	Target Neighborhood Hits	435	Shared Neighborhood Hits	36
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

SRRM1_HUMAN
NC score	0.095837 (rank : 94)	θ value	2.36792 (rank : 165)
Query Neighborhood Hits	296	Target Neighborhood Hits	690	Shared Neighborhood Hits	71
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

YLPM1_HUMAN
NC score	0.095751 (rank : 95)	θ value	3.0926 (rank : 190)
Query Neighborhood Hits	296	Target Neighborhood Hits	670	Shared Neighborhood Hits	87
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

DIAP1_MOUSE
NC score	0.095717 (rank : 96)	θ value	0.00869519 (rank : 31)
Query Neighborhood Hits	296	Target Neighborhood Hits	839	Shared Neighborhood Hits	63
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

IQEC1_HUMAN
NC score	0.095088 (rank : 97)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	296	Target Neighborhood Hits	76	Shared Neighborhood Hits	15
SwissProt Accessions	Q6DN90, O94863, Q96D85	Gene names	IQSEC1, ARFGEP100, BRAG2, KIAA0763
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 1 (ADP-ribosylation factors guanine nucleotide-exchange protein 100) (ADP-ribosylation factors guanine nucleotide-exchange protein 2) (Brefeldin-resistant Arf-GEF 2 protein).

WASIP_MOUSE
NC score	0.094629 (rank : 98)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	296	Target Neighborhood Hits	392	Shared Neighborhood Hits	68
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

P55G_HUMAN
NC score	0.094432 (rank : 99)	θ value	0.365318 (rank : 72)
Query Neighborhood Hits	296	Target Neighborhood Hits	451	Shared Neighborhood Hits	26
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

WASL_MOUSE
NC score	0.094426 (rank : 100)	θ value	1.81305 (rank : 151)
Query Neighborhood Hits	296	Target Neighborhood Hits	339	Shared Neighborhood Hits	62
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

RERE_MOUSE
NC score	0.094390 (rank : 101)	θ value	1.38821 (rank : 130)
Query Neighborhood Hits	296	Target Neighborhood Hits	785	Shared Neighborhood Hits	85
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

PDZD8_HUMAN
NC score	0.093056 (rank : 102)	θ value	0.00869519 (rank : 32)
Query Neighborhood Hits	296	Target Neighborhood Hits	185	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

FARP2_HUMAN
NC score	0.092885 (rank : 103)	θ value	0.813845 (rank : 91)
Query Neighborhood Hits	296	Target Neighborhood Hits	240	Shared Neighborhood Hits	43
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

IQEC1_MOUSE
NC score	0.092735 (rank : 104)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	296	Target Neighborhood Hits	54	Shared Neighborhood Hits	10
SwissProt Accessions	Q8R0S2, Q3TZC3, Q5DU15	Gene names	Iqsec1, Kiaa0763
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 1.

FGD1_HUMAN
NC score	0.092333 (rank : 105)	θ value	0.47712 (rank : 75)
Query Neighborhood Hits	296	Target Neighborhood Hits	367	Shared Neighborhood Hits	56
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

RGS3_HUMAN
NC score	0.091914 (rank : 106)	θ value	0.47712 (rank : 78)
Query Neighborhood Hits	296	Target Neighborhood Hits	1375	Shared Neighborhood Hits	159
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

PCLO_HUMAN
NC score	0.090854 (rank : 107)	θ value	1.38821 (rank : 129)
Query Neighborhood Hits	296	Target Neighborhood Hits	2046	Shared Neighborhood Hits	150
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

K1802_MOUSE
NC score	0.090131 (rank : 108)	θ value	1.81305 (rank : 144)
Query Neighborhood Hits	296	Target Neighborhood Hits	1596	Shared Neighborhood Hits	163
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

PCLO_MOUSE
NC score	0.089677 (rank : 109)	θ value	3.0926 (rank : 179)
Query Neighborhood Hits	296	Target Neighborhood Hits	2275	Shared Neighborhood Hits	174
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

RERE_HUMAN
NC score	0.089141 (rank : 110)	θ value	2.36792 (rank : 163)
Query Neighborhood Hits	296	Target Neighborhood Hits	779	Shared Neighborhood Hits	81
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

CS007_MOUSE
NC score	0.089123 (rank : 111)	θ value	1.38821 (rank : 116)
Query Neighborhood Hits	296	Target Neighborhood Hits	464	Shared Neighborhood Hits	60
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

AB1IP_HUMAN
NC score	0.088021 (rank : 112)	θ value	0.365318 (rank : 68)
Query Neighborhood Hits	296	Target Neighborhood Hits	213	Shared Neighborhood Hits	51
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

ATN1_HUMAN
NC score	0.087505 (rank : 113)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	296	Target Neighborhood Hits	676	Shared Neighborhood Hits	73
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

BCL9_MOUSE
NC score	0.087076 (rank : 114)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	296	Target Neighborhood Hits	770	Shared Neighborhood Hits	124
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

TCGAP_HUMAN
NC score	0.086324 (rank : 115)	θ value	6.88961 (rank : 265)
Query Neighborhood Hits	296	Target Neighborhood Hits	872	Shared Neighborhood Hits	122
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

MUC7_HUMAN
NC score	0.085405 (rank : 116)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	296	Target Neighborhood Hits	538	Shared Neighborhood Hits	68
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

CENB2_HUMAN
NC score	0.085265 (rank : 117)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	296	Target Neighborhood Hits	425	Shared Neighborhood Hits	48
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

DIAP1_HUMAN
NC score	0.084980 (rank : 118)	θ value	6.88961 (rank : 244)
Query Neighborhood Hits	296	Target Neighborhood Hits	784	Shared Neighborhood Hits	67
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

NFH_MOUSE
NC score	0.084768 (rank : 119)	θ value	0.000461057 (rank : 8)
Query Neighborhood Hits	296	Target Neighborhood Hits	2247	Shared Neighborhood Hits	151
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

SSBP4_HUMAN
NC score	0.084388 (rank : 120)	θ value	1.38821 (rank : 132)
Query Neighborhood Hits	296	Target Neighborhood Hits	753	Shared Neighborhood Hits	125
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

PKHB2_MOUSE
NC score	0.083897 (rank : 121)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	296	Target Neighborhood Hits	48	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QZC7, Q3UDH6, Q8C4I4, Q8CA27	Gene names	Plekhb2, Evt2
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 2 (Evectin-2).

NUP53_HUMAN
NC score	0.083412 (rank : 122)	θ value	0.163984 (rank : 61)
Query Neighborhood Hits	296	Target Neighborhood Hits	156	Shared Neighborhood Hits	41
SwissProt Accessions	Q8NFH5, Q4ZFZ9, Q53S95, Q8TDJ1	Gene names	NUP35, MP44, NUP53
Domain Architecture	No domain graphic available
Description	Nucleoporin NUP53 (Nuclear pore complex protein Nup53) (Nucleoporin Nup35) (35 kDa nucleoporin) (Mitotic phosphoprotein 44) (MP-44).

MBD6_HUMAN
NC score	0.083336 (rank : 123)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	296	Target Neighborhood Hits	349	Shared Neighborhood Hits	52
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

FMNL_HUMAN
NC score	0.083137 (rank : 124)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	296	Target Neighborhood Hits	529	Shared Neighborhood Hits	64
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

SFR15_HUMAN
NC score	0.083013 (rank : 125)	θ value	0.813845 (rank : 98)
Query Neighborhood Hits	296	Target Neighborhood Hits	368	Shared Neighborhood Hits	52
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

PRG4_HUMAN
NC score	0.082690 (rank : 126)	θ value	2.36792 (rank : 162)
Query Neighborhood Hits	296	Target Neighborhood Hits	764	Shared Neighborhood Hits	70
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SPR1B_MOUSE
NC score	0.082663 (rank : 127)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	296	Target Neighborhood Hits	395	Shared Neighborhood Hits	96
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

GSCR1_HUMAN
NC score	0.082184 (rank : 128)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	296	Target Neighborhood Hits	674	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

MDC1_MOUSE
NC score	0.082122 (rank : 129)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	296	Target Neighborhood Hits	998	Shared Neighborhood Hits	120
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

FGD4_MOUSE
NC score	0.082071 (rank : 130)	θ value	0.125558 (rank : 52)
Query Neighborhood Hits	296	Target Neighborhood Hits	227	Shared Neighborhood Hits	31
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

SON_MOUSE
NC score	0.082031 (rank : 131)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	296	Target Neighborhood Hits	957	Shared Neighborhood Hits	116
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

PRB4S_HUMAN
NC score	0.081979 (rank : 132)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	296	Target Neighborhood Hits	330	Shared Neighborhood Hits	52
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

WASF2_MOUSE
NC score	0.081688 (rank : 133)	θ value	1.06291 (rank : 110)
Query Neighborhood Hits	296	Target Neighborhood Hits	315	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

BSN_MOUSE
NC score	0.081535 (rank : 134)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	296	Target Neighborhood Hits	2057	Shared Neighborhood Hits	165
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CBP_MOUSE
NC score	0.081512 (rank : 135)	θ value	0.813845 (rank : 87)
Query Neighborhood Hits	296	Target Neighborhood Hits	1051	Shared Neighborhood Hits	125
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

MISS_MOUSE
NC score	0.081364 (rank : 136)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	296	Target Neighborhood Hits	444	Shared Neighborhood Hits	85
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

MDC1_HUMAN
NC score	0.080672 (rank : 137)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	296	Target Neighborhood Hits	1446	Shared Neighborhood Hits	125
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

CEND3_HUMAN
NC score	0.080452 (rank : 138)	θ value	2.36792 (rank : 153)
Query Neighborhood Hits	296	Target Neighborhood Hits	275	Shared Neighborhood Hits	56
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

CEL_HUMAN
NC score	0.080307 (rank : 139)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	296	Target Neighborhood Hits	896	Shared Neighborhood Hits	133
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

FGD6_HUMAN
NC score	0.080275 (rank : 140)	θ value	5.27518 (rank : 218)
Query Neighborhood Hits	296	Target Neighborhood Hits	237	Shared Neighborhood Hits	37
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

CJ108_HUMAN
NC score	0.080271 (rank : 141)	θ value	2.36792 (rank : 156)
Query Neighborhood Hits	296	Target Neighborhood Hits	165	Shared Neighborhood Hits	48
SwissProt Accessions	Q8N8Z3	Gene names	C10orf108
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C10orf108.

ANLN_HUMAN
NC score	0.079339 (rank : 142)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	296	Target Neighborhood Hits	222	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NQW6, Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0	Gene names	ANLN
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

PRCC_HUMAN
NC score	0.079034 (rank : 143)	θ value	0.62314 (rank : 83)
Query Neighborhood Hits	296	Target Neighborhood Hits	109	Shared Neighborhood Hits	25
SwissProt Accessions	Q92733, O00665, O00724	Gene names	PRCC, TPRC
Domain Architecture	No domain graphic available
Description	Proline-rich protein PRCC (Papillary renal cell carcinoma translocation-associated gene protein).

FHOD1_MOUSE
NC score	0.078333 (rank : 144)	θ value	1.81305 (rank : 141)
Query Neighborhood Hits	296	Target Neighborhood Hits	217	Shared Neighborhood Hits	43
SwissProt Accessions	Q6P9Q4, Q8BMK2	Gene names	Fhod1, Fhos1
Domain Architecture	No domain graphic available
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

P85B_HUMAN
NC score	0.078237 (rank : 145)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	296	Target Neighborhood Hits	543	Shared Neighborhood Hits	44
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

CENA1_HUMAN
NC score	0.078184 (rank : 146)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	296	Target Neighborhood Hits	87	Shared Neighborhood Hits	41
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

TAF4_HUMAN
NC score	0.078034 (rank : 147)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	296	Target Neighborhood Hits	687	Shared Neighborhood Hits	71
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

MYO10_HUMAN
NC score	0.077779 (rank : 148)	θ value	0.00390308 (rank : 25)
Query Neighborhood Hits	296	Target Neighborhood Hits	920	Shared Neighborhood Hits	61
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

CENB5_HUMAN
NC score	0.077624 (rank : 149)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	296	Target Neighborhood Hits	395	Shared Neighborhood Hits	42
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

FGD6_MOUSE
NC score	0.077502 (rank : 150)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	296	Target Neighborhood Hits	282	Shared Neighborhood Hits	45
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

CEND1_HUMAN
NC score	0.077470 (rank : 151)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	296	Target Neighborhood Hits	284	Shared Neighborhood Hits	47
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

P85B_MOUSE
NC score	0.077244 (rank : 152)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	296	Target Neighborhood Hits	519	Shared Neighborhood Hits	36
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

LCP2_MOUSE
NC score	0.076998 (rank : 153)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	296	Target Neighborhood Hits	177	Shared Neighborhood Hits	34
SwissProt Accessions	Q60787	Gene names	Lcp2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

CD2_HUMAN
NC score	0.076895 (rank : 154)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	296	Target Neighborhood Hits	504	Shared Neighborhood Hits	100
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

CENA2_HUMAN
NC score	0.076890 (rank : 155)	θ value	3.0926 (rank : 170)
Query Neighborhood Hits	296	Target Neighborhood Hits	83	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

GAB1_HUMAN
NC score	0.076829 (rank : 156)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	296	Target Neighborhood Hits	279	Shared Neighborhood Hits	70
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

CEND3_MOUSE
NC score	0.076596 (rank : 157)	θ value	3.0926 (rank : 171)
Query Neighborhood Hits	296	Target Neighborhood Hits	228	Shared Neighborhood Hits	50
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

CK024_HUMAN
NC score	0.076574 (rank : 158)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	296	Target Neighborhood Hits	408	Shared Neighborhood Hits	63
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

SC24C_HUMAN
NC score	0.076190 (rank : 159)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	296	Target Neighborhood Hits	662	Shared Neighborhood Hits	111
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

PKHB2_HUMAN
NC score	0.076084 (rank : 160)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	296	Target Neighborhood Hits	54	Shared Neighborhood Hits	23
SwissProt Accessions	Q96CS7, Q86W37, Q9BV75, Q9NWK1	Gene names	PLEKHB2, EVT2
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 2 (Evectin-2).

SWP70_HUMAN
NC score	0.075674 (rank : 161)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	296	Target Neighborhood Hits	973	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

NCOR2_HUMAN
NC score	0.075388 (rank : 162)	θ value	1.81305 (rank : 147)
Query Neighborhood Hits	296	Target Neighborhood Hits	870	Shared Neighborhood Hits	86
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

WASP_MOUSE
NC score	0.074371 (rank : 163)	θ value	0.62314 (rank : 85)
Query Neighborhood Hits	296	Target Neighborhood Hits	223	Shared Neighborhood Hits	44
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

3BP1_HUMAN
NC score	0.074242 (rank : 164)	θ value	1.06291 (rank : 102)
Query Neighborhood Hits	296	Target Neighborhood Hits	376	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

MAGE1_HUMAN
NC score	0.074155 (rank : 165)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	296	Target Neighborhood Hits	1389	Shared Neighborhood Hits	144
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

FGD4_HUMAN
NC score	0.073586 (rank : 166)	θ value	1.38821 (rank : 119)
Query Neighborhood Hits	296	Target Neighborhood Hits	219	Shared Neighborhood Hits	30
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

SWP70_MOUSE
NC score	0.073525 (rank : 167)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	296	Target Neighborhood Hits	1097	Shared Neighborhood Hits	60
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

WASL_HUMAN
NC score	0.073468 (rank : 168)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	296	Target Neighborhood Hits	312	Shared Neighborhood Hits	60
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

PHLB1_HUMAN
NC score	0.072657 (rank : 169)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	296	Target Neighborhood Hits	1038	Shared Neighborhood Hits	111
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

CCNK_MOUSE
NC score	0.072532 (rank : 170)	θ value	5.27518 (rank : 217)
Query Neighborhood Hits	296	Target Neighborhood Hits	350	Shared Neighborhood Hits	57
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

CRTC1_HUMAN
NC score	0.072489 (rank : 171)	θ value	1.81305 (rank : 140)
Query Neighborhood Hits	296	Target Neighborhood Hits	319	Shared Neighborhood Hits	66
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

WASF1_HUMAN
NC score	0.072008 (rank : 172)	θ value	4.03905 (rank : 214)
Query Neighborhood Hits	296	Target Neighborhood Hits	260	Shared Neighborhood Hits	46
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

BSN_HUMAN
NC score	0.071855 (rank : 173)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	296	Target Neighborhood Hits	1537	Shared Neighborhood Hits	134
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

PI5PA_HUMAN
NC score	0.071733 (rank : 174)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	296	Target Neighborhood Hits	749	Shared Neighborhood Hits	121
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PHLB1_MOUSE
NC score	0.071725 (rank : 175)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	296	Target Neighborhood Hits	678	Shared Neighborhood Hits	80
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

RCOR2_MOUSE
NC score	0.071552 (rank : 176)	θ value	0.125558 (rank : 55)
Query Neighborhood Hits	296	Target Neighborhood Hits	107	Shared Neighborhood Hits	24
SwissProt Accessions	Q8C796, Q9JMK4	Gene names	Rcor2
Domain Architecture	No domain graphic available
Description	REST corepressor 2 (M-CoREST).

TB182_HUMAN
NC score	0.071493 (rank : 177)	θ value	0.813845 (rank : 100)
Query Neighborhood Hits	296	Target Neighborhood Hits	414	Shared Neighborhood Hits	39
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

MNT_HUMAN
NC score	0.071298 (rank : 178)	θ value	8.99809 (rank : 285)
Query Neighborhood Hits	296	Target Neighborhood Hits	496	Shared Neighborhood Hits	84
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

PSL1_HUMAN
NC score	0.071193 (rank : 179)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	296	Target Neighborhood Hits	650	Shared Neighborhood Hits	126
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

PELP1_MOUSE
NC score	0.071095 (rank : 180)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	296	Target Neighborhood Hits	709	Shared Neighborhood Hits	92
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

RCOR2_HUMAN
NC score	0.071093 (rank : 181)	θ value	0.125558 (rank : 54)
Query Neighborhood Hits	296	Target Neighborhood Hits	114	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IZ40, Q96FP3	Gene names	RCOR2
Domain Architecture	No domain graphic available
Description	REST corepressor 2.

CBP_HUMAN
NC score	0.071021 (rank : 182)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	296	Target Neighborhood Hits	941	Shared Neighborhood Hits	114
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

NUMBL_HUMAN
NC score	0.070573 (rank : 183)	θ value	8.99809 (rank : 287)
Query Neighborhood Hits	296	Target Neighborhood Hits	394	Shared Neighborhood Hits	89
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

WASF1_MOUSE
NC score	0.070477 (rank : 184)	θ value	6.88961 (rank : 269)
Query Neighborhood Hits	296	Target Neighborhood Hits	261	Shared Neighborhood Hits	43
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

SPR1A_MOUSE
NC score	0.070311 (rank : 185)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	296	Target Neighborhood Hits	343	Shared Neighborhood Hits	88
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

PRB3_HUMAN
NC score	0.070104 (rank : 186)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	296	Target Neighborhood Hits	318	Shared Neighborhood Hits	43
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

CENB1_HUMAN
NC score	0.070051 (rank : 187)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	296	Target Neighborhood Hits	383	Shared Neighborhood Hits	44
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

GAB1_MOUSE
NC score	0.069528 (rank : 188)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	296	Target Neighborhood Hits	233	Shared Neighborhood Hits	67
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

BAG3_MOUSE
NC score	0.069421 (rank : 189)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	296	Target Neighborhood Hits	513	Shared Neighborhood Hits	88
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

SF3A2_HUMAN
NC score	0.069304 (rank : 190)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	296	Target Neighborhood Hits	263	Shared Neighborhood Hits	41
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

ENAH_MOUSE
NC score	0.068860 (rank : 191)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	296	Target Neighborhood Hits	919	Shared Neighborhood Hits	84
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

TARA_HUMAN
NC score	0.068838 (rank : 192)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	296	Target Neighborhood Hits	1626	Shared Neighborhood Hits	123
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

SELPL_MOUSE
NC score	0.068677 (rank : 193)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	296	Target Neighborhood Hits	588	Shared Neighborhood Hits	90
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

WIRE_HUMAN
NC score	0.068647 (rank : 194)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	296	Target Neighborhood Hits	329	Shared Neighborhood Hits	49
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

ZN207_HUMAN
NC score	0.068430 (rank : 195)	θ value	5.27518 (rank : 234)
Query Neighborhood Hits	296	Target Neighborhood Hits	326	Shared Neighborhood Hits	28
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

DAAM1_HUMAN
NC score	0.068302 (rank : 196)	θ value	3.0926 (rank : 175)
Query Neighborhood Hits	296	Target Neighborhood Hits	483	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y4D1, Q86U34, Q8N1Z8, Q8TB39	Gene names	DAAM1, KIAA0666
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

FGD5_HUMAN
NC score	0.068252 (rank : 197)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	296	Target Neighborhood Hits	235	Shared Neighborhood Hits	28
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

FGD5_MOUSE
NC score	0.068244 (rank : 198)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	296	Target Neighborhood Hits	170	Shared Neighborhood Hits	25
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

SYN1_HUMAN
NC score	0.067977 (rank : 199)	θ value	3.0926 (rank : 188)
Query Neighborhood Hits	296	Target Neighborhood Hits	419	Shared Neighborhood Hits	62
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

TARA_MOUSE
NC score	0.067938 (rank : 200)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	296	Target Neighborhood Hits	1133	Shared Neighborhood Hits	94
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

SLAP2_MOUSE
NC score	0.067162 (rank : 201)	θ value	3.0926 (rank : 184)
Query Neighborhood Hits	296	Target Neighborhood Hits	136	Shared Neighborhood Hits	23
SwissProt Accessions	Q8R4L0, Q3UU74, Q8C0K2, Q8VI42, Q9D1Z9	Gene names	Sla2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2).

DIAP2_HUMAN
NC score	0.066625 (rank : 202)	θ value	8.99809 (rank : 277)
Query Neighborhood Hits	296	Target Neighborhood Hits	342	Shared Neighborhood Hits	43
SwissProt Accessions	O60879, O60878, Q8WX06, Q8WX48, Q9UJL2	Gene names	DIAPH2, DIA
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2).

WASF4_HUMAN
NC score	0.066444 (rank : 203)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	296	Target Neighborhood Hits	282	Shared Neighborhood Hits	57
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

SFPQ_HUMAN
NC score	0.066442 (rank : 204)	θ value	5.27518 (rank : 230)
Query Neighborhood Hits	296	Target Neighborhood Hits	986	Shared Neighborhood Hits	80
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

CE025_HUMAN
NC score	0.066201 (rank : 205)	θ value	1.06291 (rank : 104)
Query Neighborhood Hits	296	Target Neighborhood Hits	114	Shared Neighborhood Hits	21
SwissProt Accessions	Q8NDZ2, Q6NXN8, Q6ZTU4, Q8IZ15	Gene names	C5orf25
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C5orf25.

MILK1_MOUSE
NC score	0.066093 (rank : 206)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	296	Target Neighborhood Hits	788	Shared Neighborhood Hits	121
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

CN032_HUMAN
NC score	0.066011 (rank : 207)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	296	Target Neighborhood Hits	267	Shared Neighborhood Hits	34
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

CO039_MOUSE
NC score	0.065666 (rank : 208)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	296	Target Neighborhood Hits	445	Shared Neighborhood Hits	83
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

FMNL_MOUSE
NC score	0.065626 (rank : 209)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	296	Target Neighborhood Hits	428	Shared Neighborhood Hits	48
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

DIAP2_MOUSE
NC score	0.065604 (rank : 210)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	296	Target Neighborhood Hits	260	Shared Neighborhood Hits	39
SwissProt Accessions	O70566, Q8C2G8	Gene names	Diaph2, Diap2
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2) (mDia3).

CN032_MOUSE
NC score	0.065585 (rank : 211)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	296	Target Neighborhood Hits	233	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

S23IP_MOUSE
NC score	0.065533 (rank : 212)	θ value	1.38821 (rank : 131)
Query Neighborhood Hits	296	Target Neighborhood Hits	363	Shared Neighborhood Hits	59
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

WIRE_MOUSE
NC score	0.065444 (rank : 213)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	296	Target Neighborhood Hits	310	Shared Neighborhood Hits	54
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

VAV2_MOUSE
NC score	0.065440 (rank : 214)	θ value	1.38821 (rank : 134)
Query Neighborhood Hits	296	Target Neighborhood Hits	456	Shared Neighborhood Hits	43
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

ANLN_MOUSE
NC score	0.065333 (rank : 215)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	296	Target Neighborhood Hits	297	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K298, Q8BL79, Q8BLB3, Q8K2N0, Q9CUY0	Gene names	Anln
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

SNPC4_HUMAN
NC score	0.065217 (rank : 216)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	296	Target Neighborhood Hits	589	Shared Neighborhood Hits	92
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

K1802_HUMAN
NC score	0.065077 (rank : 217)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	296	Target Neighborhood Hits	1378	Shared Neighborhood Hits	132
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

EP300_HUMAN
NC score	0.065044 (rank : 218)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	296	Target Neighborhood Hits	821	Shared Neighborhood Hits	91
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

MINT_MOUSE
NC score	0.064991 (rank : 219)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	296	Target Neighborhood Hits	1514	Shared Neighborhood Hits	142
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

SPRR3_HUMAN
NC score	0.064963 (rank : 220)	θ value	4.03905 (rank : 212)
Query Neighborhood Hits	296	Target Neighborhood Hits	102	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UBC9, O75597, Q4ZGI7, Q5T525, Q8NET7, Q9UDG3	Gene names	SPRR3, SPRC
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta) (Esophagin) (22 kDa pancornulin).

RSMN_HUMAN
NC score	0.064920 (rank : 221)	θ value	1.81305 (rank : 149)
Query Neighborhood Hits	296	Target Neighborhood Hits	110	Shared Neighborhood Hits	19
SwissProt Accessions	P63162, P14648, P17135	Gene names	SNRPN, HCERN3, SMN
Domain Architecture	No domain graphic available
Description	Small nuclear ribonucleoprotein-associated protein N (snRNP-N) (Sm protein N) (Sm-N) (SmN) (Sm-D) (Tissue-specific-splicing protein).

RSMN_MOUSE
NC score	0.064920 (rank : 222)	θ value	1.81305 (rank : 150)
Query Neighborhood Hits	296	Target Neighborhood Hits	110	Shared Neighborhood Hits	19
SwissProt Accessions	P63163, P14648, P17135	Gene names	Snrpn, Smn
Domain Architecture	No domain graphic available
Description	Small nuclear ribonucleoprotein-associated protein N (snRNP-N) (Sm protein N) (Sm-N) (SmN) (Sm-D) (Tissue-specific-splicing protein).

SF3A2_MOUSE
NC score	0.064835 (rank : 223)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	296	Target Neighborhood Hits	247	Shared Neighborhood Hits	41
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

CN155_HUMAN
NC score	0.064830 (rank : 224)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	296	Target Neighborhood Hits	385	Shared Neighborhood Hits	43
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

ZN750_MOUSE
NC score	0.064561 (rank : 225)	θ value	0.365318 (rank : 74)
Query Neighborhood Hits	296	Target Neighborhood Hits	346	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

CEND1_MOUSE
NC score	0.064506 (rank : 226)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	296	Target Neighborhood Hits	260	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

PRG4_MOUSE
NC score	0.063988 (rank : 227)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	296	Target Neighborhood Hits	624	Shared Neighborhood Hits	58
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SRRM2_HUMAN
NC score	0.063323 (rank : 228)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	296	Target Neighborhood Hits	1296	Shared Neighborhood Hits	95
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SRRM2_MOUSE
NC score	0.063296 (rank : 229)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	296	Target Neighborhood Hits	1470	Shared Neighborhood Hits	106
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

CIC_HUMAN
NC score	0.063244 (rank : 230)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	296	Target Neighborhood Hits	992	Shared Neighborhood Hits	120
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

MUCDL_HUMAN
NC score	0.063220 (rank : 231)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	296	Target Neighborhood Hits	777	Shared Neighborhood Hits	98
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

CS007_HUMAN
NC score	0.062730 (rank : 232)	θ value	2.36792 (rank : 157)
Query Neighborhood Hits	296	Target Neighborhood Hits	401	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

GAB2_MOUSE
NC score	0.062596 (rank : 233)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	296	Target Neighborhood Hits	220	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

CECR2_HUMAN
NC score	0.062494 (rank : 234)	θ value	6.88961 (rank : 240)
Query Neighborhood Hits	296	Target Neighborhood Hits	543	Shared Neighborhood Hits	84
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

SC24A_MOUSE
NC score	0.062472 (rank : 235)	θ value	6.88961 (rank : 261)
Query Neighborhood Hits	296	Target Neighborhood Hits	394	Shared Neighborhood Hits	82
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

NCOR2_MOUSE
NC score	0.061945 (rank : 236)	θ value	8.99809 (rank : 286)
Query Neighborhood Hits	296	Target Neighborhood Hits	790	Shared Neighborhood Hits	72
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

TXND2_HUMAN
NC score	0.061392 (rank : 237)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	296	Target Neighborhood Hits	793	Shared Neighborhood Hits	75
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

PKHB1_HUMAN
NC score	0.061193 (rank : 238)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	296	Target Neighborhood Hits	46	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UF11, Q9UBF5, Q9UI37, Q9UI44	Gene names	PLEKHB1, KPL1, PHR1
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 1 (Pleckstrin homology domain retinal protein 1) (PH domain-containing protein in retina 1) (PHRET1).

DGKK_HUMAN
NC score	0.061182 (rank : 239)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	296	Target Neighborhood Hits	378	Shared Neighborhood Hits	52
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

DAAM2_MOUSE
NC score	0.060903 (rank : 240)	θ value	3.0926 (rank : 176)
Query Neighborhood Hits	296	Target Neighborhood Hits	371	Shared Neighborhood Hits	29
SwissProt Accessions	Q80U19, Q810J5	Gene names	Daam2, Kiaa0381
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 2.

FGD3_MOUSE
NC score	0.060831 (rank : 241)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	296	Target Neighborhood Hits	257	Shared Neighborhood Hits	26
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

ALEX_HUMAN
NC score	0.060739 (rank : 242)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	296	Target Neighborhood Hits	361	Shared Neighborhood Hits	57
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

ARI1A_HUMAN
NC score	0.060613 (rank : 243)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	296	Target Neighborhood Hits	787	Shared Neighborhood Hits	94
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

VAV2_HUMAN
NC score	0.060530 (rank : 244)	θ value	5.27518 (rank : 232)
Query Neighborhood Hits	296	Target Neighborhood Hits	453	Shared Neighborhood Hits	43
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

IASPP_MOUSE
NC score	0.060438 (rank : 245)	θ value	5.27518 (rank : 222)
Query Neighborhood Hits	296	Target Neighborhood Hits	1024	Shared Neighborhood Hits	118
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

JIP1_MOUSE
NC score	0.060348 (rank : 246)	θ value	1.38821 (rank : 123)
Query Neighborhood Hits	296	Target Neighborhood Hits	259	Shared Neighborhood Hits	50
SwissProt Accessions	Q9WVI9, O35145, Q925J8, Q9R1H9, Q9R1Z1, Q9WVI7, Q9WVI8	Gene names	Mapk8ip1, Ib1, Jip1, Mapk8ip, Prkm8ip
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain-1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

WASF2_HUMAN
NC score	0.060274 (rank : 247)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	296	Target Neighborhood Hits	280	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

DIDO1_HUMAN
NC score	0.059821 (rank : 248)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	296	Target Neighborhood Hits	960	Shared Neighborhood Hits	102
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

JIP1_HUMAN
NC score	0.059661 (rank : 249)	θ value	1.38821 (rank : 122)
Query Neighborhood Hits	296	Target Neighborhood Hits	271	Shared Neighborhood Hits	48
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

ANTR1_MOUSE
NC score	0.059528 (rank : 250)	θ value	0.365318 (rank : 69)
Query Neighborhood Hits	296	Target Neighborhood Hits	143	Shared Neighborhood Hits	31
SwissProt Accessions	Q9CZ52	Gene names	Antxr1, Atr, Tem8
Domain Architecture
Description	Anthrax toxin receptor 1 precursor (Tumor endothelial marker 8).

BAT3_MOUSE
NC score	0.059493 (rank : 251)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	296	Target Neighborhood Hits	518	Shared Neighborhood Hits	83
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

FGD2_MOUSE
NC score	0.058747 (rank : 252)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	296	Target Neighborhood Hits	163	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

SFPQ_MOUSE
NC score	0.058683 (rank : 253)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	296	Target Neighborhood Hits	958	Shared Neighborhood Hits	73
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

RSMB_HUMAN
NC score	0.058660 (rank : 254)	θ value	3.0926 (rank : 182)
Query Neighborhood Hits	296	Target Neighborhood Hits	117	Shared Neighborhood Hits	18
SwissProt Accessions	P14678, Q15490, Q9UIS5	Gene names	SNRPB, COD, SNRPB1
Domain Architecture
Description	Small nuclear ribonucleoprotein-associated proteins B and B' (snRNP-B) (Sm protein B/B') (Sm-B/Sm-B') (SmB/SmB').

CABIN_HUMAN
NC score	0.058351 (rank : 255)	θ value	6.88961 (rank : 239)
Query Neighborhood Hits	296	Target Neighborhood Hits	490	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

H6ST3_HUMAN
NC score	0.057942 (rank : 256)	θ value	0.0563607 (rank : 46)
Query Neighborhood Hits	296	Target Neighborhood Hits	66	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IZP7, Q5W0L0, Q68CW6	Gene names	HS6ST3
Domain Architecture	No domain graphic available
Description	Heparan-sulfate 6-O-sulfotransferase 3 (EC 2.8.2.-) (HS6ST-3).

TP53B_MOUSE
NC score	0.057796 (rank : 257)	θ value	8.99809 (rank : 295)
Query Neighborhood Hits	296	Target Neighborhood Hits	644	Shared Neighborhood Hits	63
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

DGKH_HUMAN
NC score	0.057557 (rank : 258)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	296	Target Neighborhood Hits	255	Shared Neighborhood Hits	42
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

ANTR1_HUMAN
NC score	0.057488 (rank : 259)	θ value	1.38821 (rank : 113)
Query Neighborhood Hits	296	Target Neighborhood Hits	128	Shared Neighborhood Hits	28
SwissProt Accessions	Q9H6X2, Q96P02, Q9NVP3	Gene names	ANTXR1, ATR, TEM8
Domain Architecture
Description	Anthrax toxin receptor 1 precursor (Tumor endothelial marker 8).

GAB2_HUMAN
NC score	0.057318 (rank : 260)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	296	Target Neighborhood Hits	188	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UQC2, O60317	Gene names	GAB2, KIAA0571
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (pp100).

PRGC2_MOUSE
NC score	0.057228 (rank : 261)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	296	Target Neighborhood Hits	225	Shared Neighborhood Hits	22
SwissProt Accessions	Q8VHJ7, Q8C1C0	Gene names	Ppargc1b, Errl1, Pgc1, Pgc1b, Ppargc1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta protein) (PGC-1beta) (ERR ligand 1) (PPARGC-1-beta) (PGC-1-beta).

RIN3_HUMAN
NC score	0.056808 (rank : 262)	θ value	4.03905 (rank : 208)
Query Neighborhood Hits	296	Target Neighborhood Hits	227	Shared Neighborhood Hits	41
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

FHOD1_HUMAN
NC score	0.056799 (rank : 263)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	296	Target Neighborhood Hits	184	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y613, Q59F76, Q6Y1F2, Q76MS8, Q8N521	Gene names	FHOD1, FHOS
Domain Architecture
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

LPP_HUMAN
NC score	0.056779 (rank : 264)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	296	Target Neighborhood Hits	775	Shared Neighborhood Hits	123
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

BRD4_MOUSE
NC score	0.056557 (rank : 265)	θ value	6.88961 (rank : 238)
Query Neighborhood Hits	296	Target Neighborhood Hits	845	Shared Neighborhood Hits	60
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

FGD2_HUMAN
NC score	0.056541 (rank : 266)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	296	Target Neighborhood Hits	151	Shared Neighborhood Hits	23
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

CS016_HUMAN
NC score	0.056478 (rank : 267)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	296	Target Neighborhood Hits	310	Shared Neighborhood Hits	45
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

SELV_HUMAN
NC score	0.056136 (rank : 268)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	296	Target Neighborhood Hits	118	Shared Neighborhood Hits	22
SwissProt Accessions	P59797	Gene names	SELV
Domain Architecture	No domain graphic available
Description	Selenoprotein V.

MUC1_MOUSE
NC score	0.055945 (rank : 269)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	296	Target Neighborhood Hits	388	Shared Neighborhood Hits	32
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

K0310_HUMAN
NC score	0.055824 (rank : 270)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	296	Target Neighborhood Hits	420	Shared Neighborhood Hits	74
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

CJ078_MOUSE
NC score	0.055807 (rank : 271)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	296	Target Neighborhood Hits	559	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

LNK_MOUSE
NC score	0.055752 (rank : 272)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	296	Target Neighborhood Hits	132	Shared Neighborhood Hits	19
SwissProt Accessions	O09039	Gene names	Lnk
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

ZN385_HUMAN
NC score	0.055683 (rank : 273)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	296	Target Neighborhood Hits	614	Shared Neighborhood Hits	93
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

AMBN_HUMAN
NC score	0.055571 (rank : 274)	θ value	1.38821 (rank : 112)
Query Neighborhood Hits	296	Target Neighborhood Hits	107	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NP70, Q9H2X1, Q9H4L1	Gene names	AMBN
Domain Architecture
Description	Ameloblastin precursor.

CD248_HUMAN
NC score	0.055540 (rank : 275)	θ value	0.365318 (rank : 71)
Query Neighborhood Hits	296	Target Neighborhood Hits	679	Shared Neighborhood Hits	84
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

LNK_HUMAN
NC score	0.055398 (rank : 276)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	296	Target Neighborhood Hits	151	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UQQ2, O95184	Gene names	LNK
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

AFAD_HUMAN
NC score	0.055279 (rank : 277)	θ value	0.0330416 (rank : 39)
Query Neighborhood Hits	296	Target Neighborhood Hits	689	Shared Neighborhood Hits	34
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

PLCG2_HUMAN
NC score	0.055264 (rank : 278)	θ value	6.88961 (rank : 255)
Query Neighborhood Hits	296	Target Neighborhood Hits	280	Shared Neighborhood Hits	29
SwissProt Accessions	P16885, Q969T5	Gene names	PLCG2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV).

CDN1C_HUMAN
NC score	0.055220 (rank : 279)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	296	Target Neighborhood Hits	168	Shared Neighborhood Hits	29
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

CENG1_MOUSE
NC score	0.055197 (rank : 280)	θ value	2.36792 (rank : 155)
Query Neighborhood Hits	296	Target Neighborhood Hits	531	Shared Neighborhood Hits	39
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

K1543_MOUSE
NC score	0.055050 (rank : 281)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	296	Target Neighborhood Hits	497	Shared Neighborhood Hits	75
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

MAP1A_HUMAN
NC score	0.055011 (rank : 282)	θ value	8.99809 (rank : 283)
Query Neighborhood Hits	296	Target Neighborhood Hits	1626	Shared Neighborhood Hits	132
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

TACC2_MOUSE
NC score	0.054752 (rank : 283)	θ value	1.06291 (rank : 109)
Query Neighborhood Hits	296	Target Neighborhood Hits	774	Shared Neighborhood Hits	49
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

WASP_HUMAN
NC score	0.054565 (rank : 284)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	296	Target Neighborhood Hits	195	Shared Neighborhood Hits	34
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

HRX_HUMAN
NC score	0.054560 (rank : 285)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	296	Target Neighborhood Hits	825	Shared Neighborhood Hits	56
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

AB1IP_MOUSE
NC score	0.054553 (rank : 286)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	296	Target Neighborhood Hits	181	Shared Neighborhood Hits	35
SwissProt Accessions	Q8R5A3, O35329, Q8BRU0, Q99KV8	Gene names	Apbb1ip, Prel1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 48).

VAV3_MOUSE
NC score	0.054490 (rank : 287)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	296	Target Neighborhood Hits	404	Shared Neighborhood Hits	39
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

HD_HUMAN
NC score	0.054373 (rank : 288)	θ value	0.125558 (rank : 53)
Query Neighborhood Hits	296	Target Neighborhood Hits	165	Shared Neighborhood Hits	22
SwissProt Accessions	P42858, Q9UQB7	Gene names	HD, IT15
Domain Architecture
Description	Huntingtin (Huntington disease protein) (HD protein).

PKHB1_MOUSE
NC score	0.054202 (rank : 289)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	296	Target Neighborhood Hits	47	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QYE9, Q9QYB3, Q9QYB4, Q9QYD2, Q9QYD3	Gene names	Plekhb1, Phr1
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 1 (Pleckstrin homology domain retinal protein 1) (PH domain-containing protein in retina 1) (PHRET1).

IWS1_HUMAN
NC score	0.053996 (rank : 290)	θ value	6.88961 (rank : 249)
Query Neighborhood Hits	296	Target Neighborhood Hits	1241	Shared Neighborhood Hits	83
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

TACC2_HUMAN
NC score	0.053888 (rank : 291)	θ value	0.125558 (rank : 56)
Query Neighborhood Hits	296	Target Neighborhood Hits	856	Shared Neighborhood Hits	58
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

C43BP_MOUSE
NC score	0.053865 (rank : 292)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	296	Target Neighborhood Hits	91	Shared Neighborhood Hits	30
SwissProt Accessions	Q9EQG9, Q91WB1, Q9CU52, Q9EQG8	Gene names	Col4a3bp, Stard11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

RASA3_HUMAN
NC score	0.053681 (rank : 293)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	296	Target Neighborhood Hits	166	Shared Neighborhood Hits	34
SwissProt Accessions	Q14644	Gene names	RASA3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein).

DAAM1_MOUSE
NC score	0.053601 (rank : 294)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	296	Target Neighborhood Hits	443	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BPM0, Q80Y68, Q9CQQ2	Gene names	Daam1
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

DAAM2_HUMAN
NC score	0.053582 (rank : 295)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	296	Target Neighborhood Hits	350	Shared Neighborhood Hits	21
SwissProt Accessions	Q86T65, Q5T4U0, Q9NQI5, Q9Y4G0	Gene names	DAAM2, KIAA0381
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 2.

PELP1_HUMAN
NC score	0.053472 (rank : 296)	θ value	5.27518 (rank : 226)
Query Neighborhood Hits	296	Target Neighborhood Hits	596	Shared Neighborhood Hits	47
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

RCOR3_MOUSE
NC score	0.053405 (rank : 297)	θ value	5.27518 (rank : 227)
Query Neighborhood Hits	296	Target Neighborhood Hits	110	Shared Neighborhood Hits	21
SwissProt Accessions	Q6PGA0	Gene names	Rcor3
Domain Architecture	No domain graphic available
Description	REST corepressor 3.

TGON2_HUMAN
NC score	0.053311 (rank : 298)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	296	Target Neighborhood Hits	1037	Shared Neighborhood Hits	80
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

BCAR1_HUMAN
NC score	0.053211 (rank : 299)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	296	Target Neighborhood Hits	554	Shared Neighborhood Hits	103
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

RBM12_MOUSE
NC score	0.053210 (rank : 300)	θ value	6.88961 (rank : 259)
Query Neighborhood Hits	296	Target Neighborhood Hits	313	Shared Neighborhood Hits	41
SwissProt Accessions	Q8R4X3, Q8K373, Q8R302, Q9CS80	Gene names	Rbm12
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

PCQAP_HUMAN
NC score	0.053180 (rank : 301)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	296	Target Neighborhood Hits	549	Shared Neighborhood Hits	49
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

IWS1_MOUSE
NC score	0.052995 (rank : 302)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	296	Target Neighborhood Hits	1258	Shared Neighborhood Hits	97
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

SH21B_MOUSE
NC score	0.052924 (rank : 303)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	296	Target Neighborhood Hits	101	Shared Neighborhood Hits	15
SwissProt Accessions	O35324, Q8C268	Gene names	Sh2d1b, Eat2, Sh2d1b1
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

CASC3_MOUSE
NC score	0.052892 (rank : 304)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	296	Target Neighborhood Hits	333	Shared Neighborhood Hits	47
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

GA2L2_MOUSE
NC score	0.052864 (rank : 305)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	296	Target Neighborhood Hits	395	Shared Neighborhood Hits	88
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

OSBP1_HUMAN
NC score	0.052774 (rank : 306)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	296	Target Neighborhood Hits	180	Shared Neighborhood Hits	39
SwissProt Accessions	P22059	Gene names	OSBP, OSBP1
Domain Architecture
Description	Oxysterol-binding protein 1.

DIAP3_MOUSE
NC score	0.052752 (rank : 307)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	296	Target Neighborhood Hits	221	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z207	Gene names	Diaph3, Diap3
Domain Architecture
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3) (mDIA2) (p134mDIA2).

SLAP2_HUMAN
NC score	0.052634 (rank : 308)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	296	Target Neighborhood Hits	139	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H6Q3, Q5TH27, Q5TH28, Q8WY18, Q96QI4, Q9H135	Gene names	SLA2, C20orf156, SLAP2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2) (Modulator of antigen receptor signaling) (MARS).

BASP_HUMAN
NC score	0.052608 (rank : 309)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	296	Target Neighborhood Hits	321	Shared Neighborhood Hits	30
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

CRSP2_HUMAN
NC score	0.052369 (rank : 310)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	296	Target Neighborhood Hits	380	Shared Neighborhood Hits	72
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

ARHGF_HUMAN
NC score	0.052320 (rank : 311)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	296	Target Neighborhood Hits	214	Shared Neighborhood Hits	43
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

VAV3_HUMAN
NC score	0.052299 (rank : 312)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	296	Target Neighborhood Hits	398	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

3BP1_MOUSE
NC score	0.052110 (rank : 313)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	296	Target Neighborhood Hits	238	Shared Neighborhood Hits	37
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

RFX1_HUMAN
NC score	0.051995 (rank : 314)	θ value	0.813845 (rank : 97)
Query Neighborhood Hits	296	Target Neighborhood Hits	256	Shared Neighborhood Hits	38
SwissProt Accessions	P22670	Gene names	RFX1
Domain Architecture
Description	MHC class II regulatory factor RFX1 (RFX) (Enhancer factor C) (EF-C).

NOLC1_HUMAN
NC score	0.051975 (rank : 315)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	296	Target Neighborhood Hits	452	Shared Neighborhood Hits	37
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

WASF3_HUMAN
NC score	0.051874 (rank : 316)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	296	Target Neighborhood Hits	204	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UPY6, O94974	Gene names	WASF3, KIAA0900, SCAR3, WAVE3
Domain Architecture
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3) (Verprolin homology domain-containing protein 3).

DIAP3_HUMAN
NC score	0.051789 (rank : 317)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	296	Target Neighborhood Hits	209	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NSV4, Q5T2S7, Q5XKF6, Q6MZF0, Q6NUP0, Q86VS4, Q8NAV4	Gene names	DIAPH3, DIAP3
Domain Architecture	No domain graphic available
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3).

GRAP_MOUSE
NC score	0.051769 (rank : 318)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	296	Target Neighborhood Hits	309	Shared Neighborhood Hits	31
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

ALEX_MOUSE
NC score	0.051763 (rank : 319)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	296	Target Neighborhood Hits	197	Shared Neighborhood Hits	37
SwissProt Accessions	Q6R0H6, Q8BIR3	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

SYNJ1_HUMAN
NC score	0.051573 (rank : 320)	θ value	6.88961 (rank : 264)
Query Neighborhood Hits	296	Target Neighborhood Hits	498	Shared Neighborhood Hits	75
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

MARCS_HUMAN
NC score	0.051423 (rank : 321)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	296	Target Neighborhood Hits	204	Shared Neighborhood Hits	21
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

ENL_HUMAN
NC score	0.051367 (rank : 322)	θ value	3.0926 (rank : 177)
Query Neighborhood Hits	296	Target Neighborhood Hits	305	Shared Neighborhood Hits	31
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

FGD3_HUMAN
NC score	0.051363 (rank : 323)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	296	Target Neighborhood Hits	249	Shared Neighborhood Hits	19
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

NUP53_MOUSE
NC score	0.051304 (rank : 324)	θ value	8.99809 (rank : 288)
Query Neighborhood Hits	296	Target Neighborhood Hits	94	Shared Neighborhood Hits	20
SwissProt Accessions	Q8R4R6, Q9D7J2	Gene names	Nup35, Mp44, Nup53
Domain Architecture	No domain graphic available
Description	Nucleoporin NUP53 (Nuclear pore complex protein Nup53) (Nucleoporin Nup35) (35 kDa nucleoporin) (Mitotic phosphoprotein 44) (MP-44).

SETBP_HUMAN
NC score	0.051278 (rank : 325)	θ value	2.36792 (rank : 164)
Query Neighborhood Hits	296	Target Neighborhood Hits	305	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y6X0, Q9UEF3	Gene names	SETBP1, KIAA0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

PLCG1_HUMAN
NC score	0.051243 (rank : 326)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	296	Target Neighborhood Hits	293	Shared Neighborhood Hits	33
SwissProt Accessions	P19174, Q2V575	Gene names	PLCG1, PLC1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

MRIP_MOUSE
NC score	0.051210 (rank : 327)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	296	Target Neighborhood Hits	569	Shared Neighborhood Hits	40
SwissProt Accessions	P97434, Q3TBR5, Q3TC85, Q3TRS0, Q3U1Y8, Q3U3E4, Q5SWZ3, Q5SWZ4, Q5SWZ7, Q6P559, Q80YC8	Gene names	Mrip, Kiaa0864, Rhoip3
Domain Architecture
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (p116Rip) (RIP3).

SH21B_HUMAN
NC score	0.051134 (rank : 328)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	296	Target Neighborhood Hits	101	Shared Neighborhood Hits	14
SwissProt Accessions	O14796, Q5T0L1, Q8NI18, Q969K9	Gene names	SH2D1B, EAT2
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

BASP_MOUSE
NC score	0.051104 (rank : 329)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	296	Target Neighborhood Hits	260	Shared Neighborhood Hits	26
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

K1543_HUMAN
NC score	0.051068 (rank : 330)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	296	Target Neighborhood Hits	435	Shared Neighborhood Hits	72
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

GRAP_HUMAN
NC score	0.050831 (rank : 331)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	296	Target Neighborhood Hits	307	Shared Neighborhood Hits	31
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

PLCG1_MOUSE
NC score	0.050752 (rank : 332)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	296	Target Neighborhood Hits	314	Shared Neighborhood Hits	33
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

MINT_HUMAN
NC score	0.050582 (rank : 333)	θ value	8.99809 (rank : 284)
Query Neighborhood Hits	296	Target Neighborhood Hits	1291	Shared Neighborhood Hits	88
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

GRB7_HUMAN
NC score	0.050539 (rank : 334)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	296	Target Neighborhood Hits	156	Shared Neighborhood Hits	33
SwissProt Accessions	Q14451, Q92568, Q96DF9	Gene names	GRB7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7) (B47).

MKL1_MOUSE
NC score	0.050524 (rank : 335)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	296	Target Neighborhood Hits	667	Shared Neighborhood Hits	104
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

SYN1_MOUSE
NC score	0.050348 (rank : 336)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	296	Target Neighborhood Hits	363	Shared Neighborhood Hits	49
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

ZIMP7_MOUSE
NC score	0.050295 (rank : 337)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	296	Target Neighborhood Hits	566	Shared Neighborhood Hits	96
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

NCK2_HUMAN
NC score	0.050016 (rank : 338)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	296	Target Neighborhood Hits	310	Shared Neighborhood Hits	31
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

CENG1_HUMAN
NC score	0.049669 (rank : 339)	θ value	2.36792 (rank : 154)
Query Neighborhood Hits	296	Target Neighborhood Hits	544	Shared Neighborhood Hits	30
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

CENG3_MOUSE
NC score	0.048639 (rank : 340)	θ value	1.06291 (rank : 105)
Query Neighborhood Hits	296	Target Neighborhood Hits	467	Shared Neighborhood Hits	19
SwissProt Accessions	Q8VHH5, Q812F7	Gene names	Centg3, Agap3
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

SF3A1_HUMAN
NC score	0.045946 (rank : 341)	θ value	6.88961 (rank : 262)
Query Neighborhood Hits	296	Target Neighborhood Hits	199	Shared Neighborhood Hits	33
SwissProt Accessions	Q15459	Gene names	SF3A1, SAP114
Domain Architecture
Description	Splicing factor 3 subunit 1 (Spliceosome-associated protein 114) (SAP 114) (SF3a120).

ETV3_HUMAN
NC score	0.045538 (rank : 342)	θ value	0.813845 (rank : 90)
Query Neighborhood Hits	296	Target Neighborhood Hits	312	Shared Neighborhood Hits	46
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

B4GN4_HUMAN
NC score	0.045224 (rank : 343)	θ value	1.81305 (rank : 136)
Query Neighborhood Hits	296	Target Neighborhood Hits	131	Shared Neighborhood Hits	17
SwissProt Accessions	Q76KP1, Q96LV2	Gene names	B4GALNT4
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 1 (EC 2.4.1.244) (NGalNAc-T1) (Beta- 1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4).

CSK_MOUSE
NC score	0.045135 (rank : 344)	θ value	0.0252991 (rank : 35)
Query Neighborhood Hits	296	Target Neighborhood Hits	1009	Shared Neighborhood Hits	37
SwissProt Accessions	P41241, Q03143	Gene names	Csk
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase MPK-2) (p50CSK).

CSKI1_HUMAN
NC score	0.044943 (rank : 345)	θ value	4.03905 (rank : 194)
Query Neighborhood Hits	296	Target Neighborhood Hits	997	Shared Neighborhood Hits	115
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CENG3_HUMAN
NC score	0.044660 (rank : 346)	θ value	3.0926 (rank : 172)
Query Neighborhood Hits	296	Target Neighborhood Hits	455	Shared Neighborhood Hits	18
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

SF3A1_MOUSE
NC score	0.044572 (rank : 347)	θ value	5.27518 (rank : 229)
Query Neighborhood Hits	296	Target Neighborhood Hits	198	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K4Z5, Q8C0M7, Q8C128, Q8C175, Q921T3	Gene names	Sf3a1
Domain Architecture	No domain graphic available
Description	Splicing factor 3 subunit 1 (SF3a120).

CSK_HUMAN
NC score	0.044011 (rank : 348)	θ value	0.0563607 (rank : 44)
Query Neighborhood Hits	296	Target Neighborhood Hits	1009	Shared Neighborhood Hits	37
SwissProt Accessions	P41240, Q6FGZ6	Gene names	CSK
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase CYL).

MATK_HUMAN
NC score	0.043964 (rank : 349)	θ value	0.0330416 (rank : 40)
Query Neighborhood Hits	296	Target Neighborhood Hits	954	Shared Neighborhood Hits	36
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

MYO15_HUMAN
NC score	0.043386 (rank : 350)	θ value	1.81305 (rank : 146)
Query Neighborhood Hits	296	Target Neighborhood Hits	671	Shared Neighborhood Hits	119
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

MATK_MOUSE
NC score	0.043151 (rank : 351)	θ value	0.0431538 (rank : 43)
Query Neighborhood Hits	296	Target Neighborhood Hits	952	Shared Neighborhood Hits	36
SwissProt Accessions	P41242, Q6LE90	Gene names	Matk, Ctk, Ntk
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK).

H6ST3_MOUSE
NC score	0.043029 (rank : 352)	θ value	2.36792 (rank : 159)
Query Neighborhood Hits	296	Target Neighborhood Hits	46	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QYK4	Gene names	Hs6st3
Domain Architecture	No domain graphic available
Description	Heparan-sulfate 6-O-sulfotransferase 3 (EC 2.8.2.-) (HS6ST-3) (mHS6ST- 3).

S23IP_HUMAN
NC score	0.042950 (rank : 353)	θ value	3.0926 (rank : 183)
Query Neighborhood Hits	296	Target Neighborhood Hits	134	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y6Y8, Q8IXH5, Q9BUK5	Gene names	SEC23IP
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein (p125).

CENG2_HUMAN
NC score	0.042522 (rank : 354)	θ value	1.81305 (rank : 139)
Query Neighborhood Hits	296	Target Neighborhood Hits	471	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UPQ3, Q541S5, Q6P9D7, Q9NV93	Gene names	CENTG2, AGAP1, KIAA1099
Domain Architecture
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1).

CO3A1_HUMAN
NC score	0.042416 (rank : 355)	θ value	1.06291 (rank : 106)
Query Neighborhood Hits	296	Target Neighborhood Hits	452	Shared Neighborhood Hits	37
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

ACK1_MOUSE
NC score	0.041976 (rank : 356)	θ value	0.0736092 (rank : 47)
Query Neighborhood Hits	296	Target Neighborhood Hits	1080	Shared Neighborhood Hits	84
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

PTN23_MOUSE
NC score	0.041936 (rank : 357)	θ value	0.813845 (rank : 96)
Query Neighborhood Hits	296	Target Neighborhood Hits	726	Shared Neighborhood Hits	66
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

SYN3_HUMAN
NC score	0.041224 (rank : 358)	θ value	8.99809 (rank : 294)
Query Neighborhood Hits	296	Target Neighborhood Hits	203	Shared Neighborhood Hits	35
SwissProt Accessions	O14994	Gene names	SYN3
Domain Architecture
Description	Synapsin-3 (Synapsin III).

EPN1_MOUSE
NC score	0.040953 (rank : 359)	θ value	6.88961 (rank : 245)
Query Neighborhood Hits	296	Target Neighborhood Hits	240	Shared Neighborhood Hits	37
SwissProt Accessions	Q80VP1, O70446	Gene names	Epn1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (Intersectin-EH-binding protein 1) (Ibp1).

CA106_MOUSE
NC score	0.040943 (rank : 360)	θ value	1.38821 (rank : 115)
Query Neighborhood Hits	296	Target Neighborhood Hits	89	Shared Neighborhood Hits	14
SwissProt Accessions	Q7TN12, Q7TN27, Q8BGK3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106 homolog.

TCRG1_HUMAN
NC score	0.040447 (rank : 361)	θ value	5.27518 (rank : 231)
Query Neighborhood Hits	296	Target Neighborhood Hits	929	Shared Neighborhood Hits	58
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

ACK1_HUMAN
NC score	0.040289 (rank : 362)	θ value	1.81305 (rank : 135)
Query Neighborhood Hits	296	Target Neighborhood Hits	1140	Shared Neighborhood Hits	97
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

RBM12_HUMAN
NC score	0.040063 (rank : 363)	θ value	8.99809 (rank : 290)
Query Neighborhood Hits	296	Target Neighborhood Hits	298	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NTZ6, O94865, Q8N3B1, Q9H196	Gene names	RBM12, KIAA0765
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

FGR_HUMAN
NC score	0.039859 (rank : 364)	θ value	0.163984 (rank : 58)
Query Neighborhood Hits	296	Target Neighborhood Hits	1067	Shared Neighborhood Hits	43
SwissProt Accessions	P09769, Q9UIQ3	Gene names	FGR, SRC2
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

BMX_HUMAN
NC score	0.039414 (rank : 365)	θ value	1.38821 (rank : 114)
Query Neighborhood Hits	296	Target Neighborhood Hits	942	Shared Neighborhood Hits	57
SwissProt Accessions	P51813, O60564, Q12871	Gene names	BMX
Domain Architecture
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38).

MYST3_HUMAN
NC score	0.039286 (rank : 366)	θ value	3.0926 (rank : 178)
Query Neighborhood Hits	296	Target Neighborhood Hits	772	Shared Neighborhood Hits	47
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

NFH_HUMAN
NC score	0.037790 (rank : 367)	θ value	2.36792 (rank : 160)
Query Neighborhood Hits	296	Target Neighborhood Hits	1242	Shared Neighborhood Hits	52
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

COIA1_HUMAN
NC score	0.037323 (rank : 368)	θ value	4.03905 (rank : 193)
Query Neighborhood Hits	296	Target Neighborhood Hits	447	Shared Neighborhood Hits	51
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

SOX13_MOUSE
NC score	0.037120 (rank : 369)	θ value	4.03905 (rank : 210)
Query Neighborhood Hits	296	Target Neighborhood Hits	495	Shared Neighborhood Hits	82
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

IL3RB_HUMAN
NC score	0.037100 (rank : 370)	θ value	5.27518 (rank : 223)
Query Neighborhood Hits	296	Target Neighborhood Hits	163	Shared Neighborhood Hits	25
SwissProt Accessions	P32927	Gene names	CSF2RB, IL3RB, IL5RB
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen) (CDw131).

BMX_MOUSE
NC score	0.036736 (rank : 371)	θ value	4.03905 (rank : 192)
Query Neighborhood Hits	296	Target Neighborhood Hits	912	Shared Neighborhood Hits	52
SwissProt Accessions	P97504	Gene names	Bmx
Domain Architecture	No domain graphic available
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein homolog).

B4GN4_MOUSE
NC score	0.036046 (rank : 372)	θ value	4.03905 (rank : 191)
Query Neighborhood Hits	296	Target Neighborhood Hits	129	Shared Neighborhood Hits	25
SwissProt Accessions	Q766D5, Q8CHV2	Gene names	B4galnt4
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 1 (EC 2.4.1.244) (NGalNAc-T1) (Beta- 1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4).

CENG2_MOUSE
NC score	0.036039 (rank : 373)	θ value	8.99809 (rank : 276)
Query Neighborhood Hits	296	Target Neighborhood Hits	463	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

SNPC4_MOUSE
NC score	0.036019 (rank : 374)	θ value	4.03905 (rank : 209)
Query Neighborhood Hits	296	Target Neighborhood Hits	237	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BP86, Q6PGG7, Q80UG9, Q810L1	Gene names	Snapc4
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit).

ENAH_HUMAN
NC score	0.034996 (rank : 375)	θ value	4.03905 (rank : 195)
Query Neighborhood Hits	296	Target Neighborhood Hits	784	Shared Neighborhood Hits	61
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

S2A4R_HUMAN
NC score	0.034955 (rank : 376)	θ value	6.88961 (rank : 260)
Query Neighborhood Hits	296	Target Neighborhood Hits	54	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NR83, Q6F6I6, Q6F6I7, Q6GTK5, Q8TAH5, Q8WVW7, Q96QD3, Q9BV85	Gene names	SLC2A4RG, HDBP1
Domain Architecture	No domain graphic available
Description	SLC2A4 regulator (GLUT4 enhancer factor) (GEF) (Huntington disease gene regulatory region-binding protein 1) (HDBP-1).

MYST3_MOUSE
NC score	0.034626 (rank : 377)	θ value	6.88961 (rank : 252)
Query Neighborhood Hits	296	Target Neighborhood Hits	688	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

GR65_HUMAN
NC score	0.034535 (rank : 378)	θ value	6.88961 (rank : 248)
Query Neighborhood Hits	296	Target Neighborhood Hits	148	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BQQ3, Q8N272, Q96H42	Gene names	GORASP1, GRASP65
Domain Architecture	No domain graphic available
Description	Golgi reassembly-stacking protein 1 (Golgi reassembly-stacking protein of 65 kDa) (GRASP65) (Golgi peripheral membrane protein p65) (Golgi phosphoprotein 5) (GOLPH5).

BLK_HUMAN
NC score	0.034381 (rank : 379)	θ value	0.365318 (rank : 70)
Query Neighborhood Hits	296	Target Neighborhood Hits	994	Shared Neighborhood Hits	38
SwissProt Accessions	P51451, Q16291	Gene names	BLK
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

RFX1_MOUSE
NC score	0.034113 (rank : 380)	θ value	4.03905 (rank : 206)
Query Neighborhood Hits	296	Target Neighborhood Hits	181	Shared Neighborhood Hits	24
SwissProt Accessions	P48377	Gene names	Rfx1
Domain Architecture
Description	DNA-binding protein RFX1.

OST4_HUMAN
NC score	0.033953 (rank : 381)	θ value	0.0736092 (rank : 48)
Query Neighborhood Hits	296	Target Neighborhood Hits	95	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y661, Q5QI42, Q8NDC2	Gene names	HS3ST4, 3OST4
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 4 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4) (Heparan sulfate 3-O-sulfotransferase 4) (h3-OST-4).

MCSP_MOUSE
NC score	0.033560 (rank : 382)	θ value	4.03905 (rank : 202)
Query Neighborhood Hits	296	Target Neighborhood Hits	108	Shared Neighborhood Hits	8
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

MUCDL_MOUSE
NC score	0.033447 (rank : 383)	θ value	5.27518 (rank : 224)
Query Neighborhood Hits	296	Target Neighborhood Hits	461	Shared Neighborhood Hits	45
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

GCH1_HUMAN
NC score	0.033419 (rank : 384)	θ value	5.27518 (rank : 220)
Query Neighborhood Hits	296	Target Neighborhood Hits	69	Shared Neighborhood Hits	11
SwissProt Accessions	P30793, Q9Y4I8	Gene names	GCH1, DYT5, GCH
Domain Architecture
Description	GTP cyclohydrolase I (EC 3.5.4.16) (GTP-CH-I).

SF3B4_HUMAN
NC score	0.032998 (rank : 385)	θ value	6.88961 (rank : 263)
Query Neighborhood Hits	296	Target Neighborhood Hits	445	Shared Neighborhood Hits	44
SwissProt Accessions	Q15427	Gene names	SF3B4, SAP49
Domain Architecture
Description	Splicing factor 3B subunit 4 (Spliceosome-associated protein 49) (SAP 49) (SF3b50) (Pre-mRNA-splicing factor SF3b 49 kDa subunit).

AMOT_HUMAN
NC score	0.032610 (rank : 386)	θ value	6.88961 (rank : 237)
Query Neighborhood Hits	296	Target Neighborhood Hits	712	Shared Neighborhood Hits	50
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

PLXB1_HUMAN
NC score	0.032418 (rank : 387)	θ value	0.813845 (rank : 95)
Query Neighborhood Hits	296	Target Neighborhood Hits	360	Shared Neighborhood Hits	53
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

PO6F2_MOUSE
NC score	0.032369 (rank : 388)	θ value	4.03905 (rank : 205)
Query Neighborhood Hits	296	Target Neighborhood Hits	639	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

ZN687_HUMAN
NC score	0.031380 (rank : 389)	θ value	1.06291 (rank : 111)
Query Neighborhood Hits	296	Target Neighborhood Hits	1244	Shared Neighborhood Hits	111
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

AGT2_HUMAN
NC score	0.031287 (rank : 390)	θ value	5.27518 (rank : 216)
Query Neighborhood Hits	296	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BYV1, Q53FB4, Q53FY7, Q53G03, Q5W7Q1	Gene names	AGXT2, AGT2
Domain Architecture
Description	Alanine--glyoxylate aminotransferase 2, mitochondrial precursor (EC 2.6.1.44) ((R)-3-amino-2-methylpropionate--pyruvate transaminase) (EC 2.6.1.40) (AGT 2) (Beta-alanine-pyruvate aminotransferase) (Beta- ALAAT II) (D-AIBAT).

SPEG_MOUSE
NC score	0.031247 (rank : 391)	θ value	3.0926 (rank : 185)
Query Neighborhood Hits	296	Target Neighborhood Hits	1959	Shared Neighborhood Hits	131
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

ASPP1_HUMAN
NC score	0.030890 (rank : 392)	θ value	2.36792 (rank : 152)
Query Neighborhood Hits	296	Target Neighborhood Hits	956	Shared Neighborhood Hits	55
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

CJ047_MOUSE
NC score	0.030876 (rank : 393)	θ value	6.88961 (rank : 242)
Query Neighborhood Hits	296	Target Neighborhood Hits	76	Shared Neighborhood Hits	15
SwissProt Accessions	Q8C5R2, Q8R017, Q8R2Z9	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf47 homolog.

CA106_HUMAN
NC score	0.030258 (rank : 394)	θ value	8.99809 (rank : 273)
Query Neighborhood Hits	296	Target Neighborhood Hits	124	Shared Neighborhood Hits	14
SwissProt Accessions	Q3KP66, Q9NV65, Q9NVI0	Gene names	C1orf106
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106.

SF04_MOUSE
NC score	0.030187 (rank : 395)	θ value	8.99809 (rank : 291)
Query Neighborhood Hits	296	Target Neighborhood Hits	95	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CH02, Q8R094	Gene names	Sf4
Domain Architecture	No domain graphic available
Description	Splicing factor 4.

PO6F2_HUMAN
NC score	0.029925 (rank : 396)	θ value	4.03905 (rank : 204)
Query Neighborhood Hits	296	Target Neighborhood Hits	618	Shared Neighborhood Hits	46
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

DAZP1_MOUSE
NC score	0.029498 (rank : 397)	θ value	1.38821 (rank : 118)
Query Neighborhood Hits	296	Target Neighborhood Hits	313	Shared Neighborhood Hits	32
SwissProt Accessions	Q9JII5	Gene names	Dazap1
Domain Architecture
Description	DAZ-associated protein 1 (Deleted in azoospermia-associated protein 1).

STRC_MOUSE
NC score	0.029232 (rank : 398)	θ value	3.0926 (rank : 187)
Query Neighborhood Hits	296	Target Neighborhood Hits	89	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VIM6	Gene names	Strc
Domain Architecture	No domain graphic available
Description	Stereocilin precursor.

DAZP1_HUMAN
NC score	0.029194 (rank : 399)	θ value	1.38821 (rank : 117)
Query Neighborhood Hits	296	Target Neighborhood Hits	313	Shared Neighborhood Hits	30
SwissProt Accessions	Q96EP5, Q96MJ3, Q9NRR9	Gene names	DAZAP1
Domain Architecture
Description	DAZ-associated protein 1 (Deleted in azoospermia-associated protein 1).

CCD96_MOUSE
NC score	0.028308 (rank : 400)	θ value	3.0926 (rank : 168)
Query Neighborhood Hits	296	Target Neighborhood Hits	704	Shared Neighborhood Hits	31
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

UBP51_HUMAN
NC score	0.028180 (rank : 401)	θ value	0.125558 (rank : 57)
Query Neighborhood Hits	296	Target Neighborhood Hits	162	Shared Neighborhood Hits	17
SwissProt Accessions	Q70EK9, Q8IWJ8	Gene names	USP51
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51).

CTHR1_HUMAN
NC score	0.028164 (rank : 402)	θ value	3.0926 (rank : 173)
Query Neighborhood Hits	296	Target Neighborhood Hits	126	Shared Neighborhood Hits	5
SwissProt Accessions	Q96CG8, Q6UW91, Q8IX63	Gene names	CTHRC1
Domain Architecture	No domain graphic available
Description	Collagen triple helix repeat-containing protein 1 precursor (NMTC1 protein).

CTHR1_MOUSE
NC score	0.028134 (rank : 403)	θ value	3.0926 (rank : 174)
Query Neighborhood Hits	296	Target Neighborhood Hits	123	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D1D6	Gene names	Cthrc1
Domain Architecture	No domain graphic available
Description	Collagen triple helix repeat-containing protein 1 precursor.

MAST4_HUMAN
NC score	0.027918 (rank : 404)	θ value	1.38821 (rank : 124)
Query Neighborhood Hits	296	Target Neighborhood Hits	1804	Shared Neighborhood Hits	116
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

PF21A_HUMAN
NC score	0.027737 (rank : 405)	θ value	6.88961 (rank : 253)
Query Neighborhood Hits	296	Target Neighborhood Hits	303	Shared Neighborhood Hits	20
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

PF21A_MOUSE
NC score	0.026938 (rank : 406)	θ value	6.88961 (rank : 254)
Query Neighborhood Hits	296	Target Neighborhood Hits	285	Shared Neighborhood Hits	18
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

M3K9_HUMAN
NC score	0.026016 (rank : 407)	θ value	0.47712 (rank : 77)
Query Neighborhood Hits	296	Target Neighborhood Hits	1123	Shared Neighborhood Hits	41
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

TBC10_MOUSE
NC score	0.025726 (rank : 408)	θ value	1.38821 (rank : 133)
Query Neighborhood Hits	296	Target Neighborhood Hits	94	Shared Neighborhood Hits	12
SwissProt Accessions	P58802	Gene names	Tbc1d10a, Epi64, Tbc1d10
Domain Architecture
Description	TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa) (EPI64 protein).

RIPK3_MOUSE
NC score	0.025694 (rank : 409)	θ value	0.62314 (rank : 84)
Query Neighborhood Hits	296	Target Neighborhood Hits	867	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QZL0	Gene names	Ripk3, Rip3
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (mRIP3).

TNK1_MOUSE
NC score	0.025390 (rank : 410)	θ value	6.88961 (rank : 266)
Query Neighborhood Hits	296	Target Neighborhood Hits	806	Shared Neighborhood Hits	27
SwissProt Accessions	Q99ML2, Q8CCC4, Q8K0X9, Q91V11	Gene names	Tnk1, Kos1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (Kinase of embryonic stem cells).

RGL2_HUMAN
NC score	0.024535 (rank : 411)	θ value	4.03905 (rank : 207)
Query Neighborhood Hits	296	Target Neighborhood Hits	45	Shared Neighborhood Hits	10
SwissProt Accessions	O15211, Q9Y3F3	Gene names	RGL2, RAB2L
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator-like 2 (RalGDS-like factor) (RAS-associated protein RAB2L).

TITIN_HUMAN
NC score	0.024440 (rank : 412)	θ value	0.813845 (rank : 101)
Query Neighborhood Hits	296	Target Neighborhood Hits	2923	Shared Neighborhood Hits	116
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

ZDHC8_HUMAN
NC score	0.024199 (rank : 413)	θ value	5.27518 (rank : 233)
Query Neighborhood Hits	296	Target Neighborhood Hits	234	Shared Neighborhood Hits	36
SwissProt Accessions	Q9ULC8, Q6ICL1, Q6ZNF5, Q7Z6L9	Gene names	ZDHHC8, KIAA1292, ZDHHCL1, ZNF378
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8) (Zinc finger protein 378).

ERBB2_MOUSE
NC score	0.023856 (rank : 414)	θ value	6.88961 (rank : 246)
Query Neighborhood Hits	296	Target Neighborhood Hits	918	Shared Neighborhood Hits	32
SwissProt Accessions	P70424, Q61525, Q6ZPE0	Gene names	Erbb2, Kiaa3023, Neu
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene).

ESX1L_HUMAN
NC score	0.023569 (rank : 415)	θ value	0.813845 (rank : 89)
Query Neighborhood Hits	296	Target Neighborhood Hits	498	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N693, Q7Z6K7	Gene names	ESX1L, ESX1R
Domain Architecture
Description	Extraembryonic, spermatogenesis, homeobox 1-like protein.

SHAN2_HUMAN
NC score	0.023431 (rank : 416)	θ value	8.99809 (rank : 292)
Query Neighborhood Hits	296	Target Neighborhood Hits	346	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

CCD21_MOUSE
NC score	0.022322 (rank : 417)	θ value	1.81305 (rank : 138)
Query Neighborhood Hits	296	Target Neighborhood Hits	1135	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

ESPL1_MOUSE
NC score	0.022162 (rank : 418)	θ value	4.03905 (rank : 196)
Query Neighborhood Hits	296	Target Neighborhood Hits	67	Shared Neighborhood Hits	11
SwissProt Accessions	P60330	Gene names	Espl1, Esp1, Kiaa0165
Domain Architecture
Description	Separin (EC 3.4.22.49) (Separase) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein).

SREC2_HUMAN
NC score	0.022003 (rank : 419)	θ value	3.0926 (rank : 186)
Query Neighborhood Hits	296	Target Neighborhood Hits	645	Shared Neighborhood Hits	37
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

TTBK1_HUMAN
NC score	0.021639 (rank : 420)	θ value	6.88961 (rank : 267)
Query Neighborhood Hits	296	Target Neighborhood Hits	1058	Shared Neighborhood Hits	60
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

TRRAP_HUMAN
NC score	0.020943 (rank : 421)	θ value	4.03905 (rank : 213)
Query Neighborhood Hits	296	Target Neighborhood Hits	117	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y4A5, O75218, Q9Y631, Q9Y6H4	Gene names	TRRAP, PAF400
Domain Architecture
Description	Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog).

WFS1_MOUSE
NC score	0.020929 (rank : 422)	θ value	4.03905 (rank : 215)
Query Neighborhood Hits	296	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	P56695, Q9Z276	Gene names	Wfs1
Domain Architecture	No domain graphic available
Description	Wolframin.

SOX17_MOUSE
NC score	0.020768 (rank : 423)	θ value	4.03905 (rank : 211)
Query Neighborhood Hits	296	Target Neighborhood Hits	223	Shared Neighborhood Hits	30
SwissProt Accessions	Q61473, Q61472, Q62248	Gene names	Sox17, Sox-17
Domain Architecture
Description	Transcription factor SOX-17.

CUTL2_MOUSE
NC score	0.020720 (rank : 424)	θ value	6.88961 (rank : 243)
Query Neighborhood Hits	296	Target Neighborhood Hits	771	Shared Neighborhood Hits	45
SwissProt Accessions	P70298	Gene names	Cutl2
Domain Architecture
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

FOG1_HUMAN
NC score	0.020484 (rank : 425)	θ value	4.03905 (rank : 197)
Query Neighborhood Hits	296	Target Neighborhood Hits	981	Shared Neighborhood Hits	51
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

IRX3_HUMAN
NC score	0.020399 (rank : 426)	θ value	8.99809 (rank : 282)
Query Neighborhood Hits	296	Target Neighborhood Hits	342	Shared Neighborhood Hits	26
SwissProt Accessions	P78415, Q7Z4A4, Q7Z4A5, Q8IVC6	Gene names	IRX3, IRXB1
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-3 (Iroquois homeobox protein 3) (Homeodomain protein IRXB1).

GGA2_HUMAN
NC score	0.019469 (rank : 427)	θ value	4.03905 (rank : 199)
Query Neighborhood Hits	296	Target Neighborhood Hits	114	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UJY4, O14564, Q9NYN2, Q9UPS2	Gene names	GGA2, KIAA1080
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA2 (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (Gamma-adaptin-related protein 2) (VHS domain and ear domain of gamma-adaptin) (Vear).

LTBP4_MOUSE
NC score	0.019202 (rank : 428)	θ value	0.813845 (rank : 92)
Query Neighborhood Hits	296	Target Neighborhood Hits	607	Shared Neighborhood Hits	33
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

MICA1_HUMAN
NC score	0.019003 (rank : 429)	θ value	1.81305 (rank : 145)
Query Neighborhood Hits	296	Target Neighborhood Hits	279	Shared Neighborhood Hits	26
SwissProt Accessions	Q8TDZ2, Q7Z633, Q8IVS9, Q96G47, Q9H6X6, Q9H7I0, Q9HAA1, Q9UFF7	Gene names	MICAL1, MICAL, NICAL
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

CD2L7_HUMAN
NC score	0.018560 (rank : 430)	θ value	3.0926 (rank : 169)
Query Neighborhood Hits	296	Target Neighborhood Hits	1275	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

RAD9A_MOUSE
NC score	0.018402 (rank : 431)	θ value	6.88961 (rank : 258)
Query Neighborhood Hits	296	Target Neighborhood Hits	47	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z0F6, Q8QZZ3	Gene names	Rad9a, Rad9
Domain Architecture	No domain graphic available
Description	Cell cycle checkpoint control protein RAD9A (EC 3.1.11.2) (DNA repair exonuclease rad9 homolog A) (Rad9-like protein) (mRAD9).

ZDHC8_MOUSE
NC score	0.018035 (rank : 432)	θ value	6.88961 (rank : 271)
Query Neighborhood Hits	296	Target Neighborhood Hits	243	Shared Neighborhood Hits	25
SwissProt Accessions	Q5Y5T5, Q7TNF7	Gene names	Zdhhc8
Domain Architecture	No domain graphic available
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8).

ZO2_MOUSE
NC score	0.018013 (rank : 433)	θ value	2.36792 (rank : 166)
Query Neighborhood Hits	296	Target Neighborhood Hits	296	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

DHX37_HUMAN
NC score	0.017314 (rank : 434)	θ value	2.36792 (rank : 158)
Query Neighborhood Hits	296	Target Neighborhood Hits	133	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IY37, Q9BUI7, Q9P211	Gene names	DHX37, DDX37, KIAA1517
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX37 (EC 3.6.1.-) (DEAH box protein 37).

UBQL3_HUMAN
NC score	0.017229 (rank : 435)	θ value	6.88961 (rank : 268)
Query Neighborhood Hits	296	Target Neighborhood Hits	141	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H347, Q9NRE0	Gene names	UBQLN3
Domain Architecture
Description	Ubiquilin-3.

HXA3_MOUSE
NC score	0.016628 (rank : 436)	θ value	8.99809 (rank : 280)
Query Neighborhood Hits	296	Target Neighborhood Hits	558	Shared Neighborhood Hits	50
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

FA53C_HUMAN
NC score	0.016609 (rank : 437)	θ value	8.99809 (rank : 279)
Query Neighborhood Hits	296	Target Neighborhood Hits	29	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NYF3	Gene names	FAM53C, C5orf6
Domain Architecture	No domain graphic available
Description	Protein FAM53C.

YTHD1_HUMAN
NC score	0.016008 (rank : 438)	θ value	6.88961 (rank : 270)
Query Neighborhood Hits	296	Target Neighborhood Hits	71	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BYJ9, Q8N3G5, Q8TBT1, Q96AN4, Q96S57, Q9BTI7, Q9NX79	Gene names	YTHDF1, C20orf21
Domain Architecture
Description	YTH domain family protein 1 (Dermatomyositis associated with cancer putative autoantigen 1) (DACA-1).

EGR4_HUMAN
NC score	0.015877 (rank : 439)	θ value	0.0431538 (rank : 42)
Query Neighborhood Hits	296	Target Neighborhood Hits	939	Shared Neighborhood Hits	66
SwissProt Accessions	Q05215	Gene names	EGR4
Domain Architecture
Description	Early growth response protein 4 (EGR-4) (AT133).

AKAP1_HUMAN
NC score	0.015353 (rank : 440)	θ value	6.88961 (rank : 236)
Query Neighborhood Hits	296	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	Q92667, Q13320, Q9BW14	Gene names	AKAP1, AKAP149
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (A-kinase anchor protein 149 kDa) (AKAP 149) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein 84) (S-AKAP84).

FOXK1_MOUSE
NC score	0.015240 (rank : 441)	θ value	4.03905 (rank : 198)
Query Neighborhood Hits	296	Target Neighborhood Hits	215	Shared Neighborhood Hits	34
SwissProt Accessions	P42128, O35939	Gene names	Foxk1, Mnf
Domain Architecture
Description	Forkhead box protein K1 (Myocyte nuclear factor) (MNF).

CCD1A_MOUSE
NC score	0.014883 (rank : 442)	θ value	8.99809 (rank : 274)
Query Neighborhood Hits	296	Target Neighborhood Hits	83	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K1A6, Q2MJB5, Q8R3Z4	Gene names	Cc2d1a
Domain Architecture	No domain graphic available
Description	Coiled-coil and C2 domain-containing protein 1A (Five repressor element under dual repression-binding protein 1) (FRE under dual repression-binding protein 1) (Freud-1).

PKN3_MOUSE
NC score	0.014191 (rank : 443)	θ value	0.813845 (rank : 94)
Query Neighborhood Hits	296	Target Neighborhood Hits	1009	Shared Neighborhood Hits	45
SwissProt Accessions	Q8K045	Gene names	Pkn3, Pknbeta
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

PCD15_HUMAN
NC score	0.013401 (rank : 444)	θ value	2.36792 (rank : 161)
Query Neighborhood Hits	296	Target Neighborhood Hits	289	Shared Neighborhood Hits	28
SwissProt Accessions	Q96QU1, Q96QT8	Gene names	PCDH15
Domain Architecture
Description	Protocadherin-15 precursor.

MTR1L_HUMAN
NC score	0.013242 (rank : 445)	θ value	0.0961366 (rank : 51)
Query Neighborhood Hits	296	Target Neighborhood Hits	1180	Shared Neighborhood Hits	41
SwissProt Accessions	Q13585	Gene names	GPR50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).

DMRTA_HUMAN
NC score	0.012751 (rank : 446)	θ value	8.99809 (rank : 278)
Query Neighborhood Hits	296	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q5VZB9, Q8N8Y9, Q9H4B9	Gene names	DMRTA1, DMO
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor A1.

HME1_MOUSE
NC score	0.012450 (rank : 447)	θ value	4.03905 (rank : 201)
Query Neighborhood Hits	296	Target Neighborhood Hits	397	Shared Neighborhood Hits	21
SwissProt Accessions	P09065	Gene names	En1, En-1
Domain Architecture
Description	Homeobox protein engrailed-1 (Mo-En-1).

HXB4_HUMAN
NC score	0.011887 (rank : 448)	θ value	1.38821 (rank : 121)
Query Neighborhood Hits	296	Target Neighborhood Hits	376	Shared Neighborhood Hits	22
SwissProt Accessions	P17483, Q9NTA0	Gene names	HOXB4, HOX2F
Domain Architecture
Description	Homeobox protein Hox-B4 (Hox-2F) (Hox-2.6).

REEP4_HUMAN
NC score	0.011530 (rank : 449)	θ value	5.27518 (rank : 228)
Query Neighborhood Hits	296	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H6H4, Q86VL1, Q9H6I5, Q9HBP4	Gene names	REEP4, C8orf20
Domain Architecture	No domain graphic available
Description	Receptor expression-enhancing protein 4.

M4K4_HUMAN
NC score	0.011526 (rank : 450)	θ value	6.88961 (rank : 251)
Query Neighborhood Hits	296	Target Neighborhood Hits	1589	Shared Neighborhood Hits	44
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

P53_HUMAN
NC score	0.011414 (rank : 451)	θ value	8.99809 (rank : 289)
Query Neighborhood Hits	296	Target Neighborhood Hits	42	Shared Neighborhood Hits	5
SwissProt Accessions	P04637, Q15086, Q15087, Q15088, Q16535, Q16807, Q16808, Q16809, Q16810, Q16811, Q16848, Q86UG1, Q8J016, Q99659, Q9BTM4, Q9HAQ8, Q9NP68, Q9NPJ2, Q9NZD0, Q9UBI2, Q9UQ61	Gene names	TP53, P53
Domain Architecture
Description	Cellular tumor antigen p53 (Tumor suppressor p53) (Phosphoprotein p53) (Antigen NY-CO-13).

FOXL2_HUMAN
NC score	0.011108 (rank : 452)	θ value	6.88961 (rank : 247)
Query Neighborhood Hits	296	Target Neighborhood Hits	142	Shared Neighborhood Hits	17
SwissProt Accessions	P58012, Q4ZGJ3	Gene names	FOXL2
Domain Architecture
Description	Forkhead box protein L2.

MYL4_HUMAN
NC score	0.009413 (rank : 453)	θ value	4.03905 (rank : 203)
Query Neighborhood Hits	296	Target Neighborhood Hits	66	Shared Neighborhood Hits	4
SwissProt Accessions	P12829, P11783	Gene names	MYL4, MLC1
Domain Architecture
Description	Myosin light polypeptide 4 (Myosin light chain 1, embryonic muscle/atrial isoform) (Myosin light chain alkali, GT-1 isoform).

ACRO_HUMAN
NC score	0.008935 (rank : 454)	θ value	0.813845 (rank : 86)
Query Neighborhood Hits	296	Target Neighborhood Hits	291	Shared Neighborhood Hits	27
SwissProt Accessions	P10323, Q6ICK2	Gene names	ACR, ACRS
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

DRD4_HUMAN
NC score	0.008926 (rank : 455)	θ value	0.813845 (rank : 88)
Query Neighborhood Hits	296	Target Neighborhood Hits	886	Shared Neighborhood Hits	17
SwissProt Accessions	P21917	Gene names	DRD4
Domain Architecture
Description	D(4) dopamine receptor (Dopamine D4 receptor) (D(2C) dopamine receptor).

FOXQ1_HUMAN
NC score	0.008674 (rank : 456)	θ value	5.27518 (rank : 219)
Query Neighborhood Hits	296	Target Neighborhood Hits	115	Shared Neighborhood Hits	9
SwissProt Accessions	Q9C009, Q9NS06	Gene names	FOXQ1, HFH1
Domain Architecture
Description	Forkhead box protein Q1 (Hepatocyte nuclear factor 3 forkhead homolog 1) (HNF-3/forkhead-like protein 1) (HFH-1).

HERC5_HUMAN
NC score	0.008239 (rank : 457)	θ value	4.03905 (rank : 200)
Query Neighborhood Hits	296	Target Neighborhood Hits	66	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UII4	Gene names	HERC5, CEB1, CEBP1
Domain Architecture
Description	HECT domain and RCC1-like domain-containing protein 5 (Cyclin-E- binding protein 1).

PCD16_HUMAN
NC score	0.005429 (rank : 458)	θ value	5.27518 (rank : 225)
Query Neighborhood Hits	296	Target Neighborhood Hits	245	Shared Neighborhood Hits	11
SwissProt Accessions	Q96JQ0, O15098	Gene names	DCHS1, CDH19, FIB1, KIAA1773, PCDH16
Domain Architecture
Description	Protocadherin-16 precursor (Dachsous 1) (Cadherin-19) (Fibroblast cadherin 1).

ZN219_HUMAN
NC score	0.004930 (rank : 459)	θ value	8.99809 (rank : 296)
Query Neighborhood Hits	296	Target Neighborhood Hits	876	Shared Neighborhood Hits	39
SwissProt Accessions	Q9P2Y4, Q8IYC1, Q9BW28	Gene names	ZNF219
Domain Architecture	No domain graphic available
Description	Zinc finger protein 219.

HXD9_HUMAN
NC score	0.004386 (rank : 460)	θ value	8.99809 (rank : 281)
Query Neighborhood Hits	296	Target Neighborhood Hits	352	Shared Neighborhood Hits	12
SwissProt Accessions	P28356	Gene names	HOXD9, HOX4C
Domain Architecture
Description	Homeobox protein Hox-D9 (Hox-4C) (Hox-5.2).

CELR2_HUMAN
NC score	0.004213 (rank : 461)	θ value	6.88961 (rank : 241)
Query Neighborhood Hits	296	Target Neighborhood Hits	657	Shared Neighborhood Hits	17
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

CELR2_MOUSE
NC score	0.004099 (rank : 462)	θ value	8.99809 (rank : 275)
Query Neighborhood Hits	296	Target Neighborhood Hits	584	Shared Neighborhood Hits	14
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

POGZ_MOUSE
NC score	0.003575 (rank : 463)	θ value	6.88961 (rank : 256)
Query Neighborhood Hits	296	Target Neighborhood Hits	765	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BZH4, Q4VA94, Q80TZ8, Q8C0K1, Q8K294	Gene names	Pogz, Kiaa0461
Domain Architecture
Description	Pogo transposable element with ZNF domain.

ZN628_HUMAN
NC score	0.001532 (rank : 464)	θ value	5.27518 (rank : 235)
Query Neighborhood Hits	296	Target Neighborhood Hits	814	Shared Neighborhood Hits	24
SwissProt Accessions	Q5EBL2, Q86X34	Gene names	ZNF628
Domain Architecture	No domain graphic available
Description	Zinc finger protein 628.

ZN206_HUMAN
NC score	0.001407 (rank : 465)	θ value	0.21417 (rank : 67)
Query Neighborhood Hits	296	Target Neighborhood Hits	853	Shared Neighborhood Hits	31
SwissProt Accessions	Q96SZ4	Gene names	ZNF206, ZSCAN10
Domain Architecture	No domain graphic available
Description	Zinc finger protein 206 (Zinc finger and SCAN domain-containing protein 10).

ATS8_HUMAN
NC score	0.001166 (rank : 466)	θ value	8.99809 (rank : 272)
Query Neighborhood Hits	296	Target Neighborhood Hits	145	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UP79, Q9NZS0	Gene names	ADAMTS8, METH2
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2) (METH- 8).

KLF16_HUMAN
NC score	-0.000067 (rank : 467)	θ value	6.88961 (rank : 250)
Query Neighborhood Hits	296	Target Neighborhood Hits	737	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BXK1	Gene names	KLF16, BTEB4, NSLP2
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 16 (Transcription factor BTEB4) (Basic transcription element-binding protein 4) (BTE-binding protein 4) (Novel Sp1-like zinc finger transcription factor 2) (Transcription factor NSLP2).