Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : ESPL1_MOUSE

For an explanation of this page, click here

ESPL1_MOUSE
SwissProt Accessions	P60330	Gene names	Espl1, Esp1, Kiaa0165
Domain Architecture
Description	Separin (EC 3.4.22.49) (Separase) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ESPL1_HUMAN
θ value	0 (rank : 1)	NC score	0.972047 (rank : 2)
Query Neighborhood Hits	67	Target Neighborhood Hits	95	Shared Neighborhood Hits	7
SwissProt Accessions	Q14674	Gene names	ESPL1, ESP1, KIAA0165
Domain Architecture
Description	Separin (EC 3.4.22.49) (Separase) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein).

ESPL1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	67	Target Neighborhood Hits	67	Shared Neighborhood Hits	67
SwissProt Accessions	P60330	Gene names	Espl1, Esp1, Kiaa0165
Domain Architecture
Description	Separin (EC 3.4.22.49) (Separase) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein).

MDC1_HUMAN
θ value	5.44631e-05 (rank : 3)	NC score	0.068366 (rank : 4)
Query Neighborhood Hits	67	Target Neighborhood Hits	1446	Shared Neighborhood Hits	26
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

BTBDC_HUMAN
θ value	0.0193708 (rank : 4)	NC score	0.092385 (rank : 3)
Query Neighborhood Hits	67	Target Neighborhood Hits	248	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

SPEG_MOUSE
θ value	0.0252991 (rank : 5)	NC score	0.019052 (rank : 31)
Query Neighborhood Hits	67	Target Neighborhood Hits	1959	Shared Neighborhood Hits	13
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

UBP31_HUMAN
θ value	0.0330416 (rank : 6)	NC score	0.039537 (rank : 7)
Query Neighborhood Hits	67	Target Neighborhood Hits	293	Shared Neighborhood Hits	5
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

CP250_HUMAN
θ value	0.0736092 (rank : 7)	NC score	0.024382 (rank : 20)
Query Neighborhood Hits	67	Target Neighborhood Hits	1805	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

SPEG_HUMAN
θ value	0.125558 (rank : 8)	NC score	0.017680 (rank : 35)
Query Neighborhood Hits	67	Target Neighborhood Hits	1762	Shared Neighborhood Hits	11
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

ENL_HUMAN
θ value	0.279714 (rank : 9)	NC score	0.054674 (rank : 6)
Query Neighborhood Hits	67	Target Neighborhood Hits	305	Shared Neighborhood Hits	7
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

ZN395_HUMAN
θ value	0.365318 (rank : 10)	NC score	0.062745 (rank : 5)
Query Neighborhood Hits	67	Target Neighborhood Hits	64	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H8N7, Q6F6H2, Q9BY72, Q9NPB2, Q9NS57, Q9NS58, Q9NS59	Gene names	ZNF395, HDBP2, PBF
Domain Architecture	No domain graphic available
Description	Zinc finger protein 395 (Papillomavirus-binding factor) (Papillomavirus regulatory factor 1) (PRF-1) (Huntington disease gene regulatory region-binding protein 2) (HDBP-2) (HD gene regulatory region-binding protein 2) (HD-regulating factor 2) (HDRF-2).

AKAP9_HUMAN
θ value	0.47712 (rank : 11)	NC score	0.026525 (rank : 18)
Query Neighborhood Hits	67	Target Neighborhood Hits	1710	Shared Neighborhood Hits	16
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

TRAF2_MOUSE
θ value	0.47712 (rank : 12)	NC score	0.031188 (rank : 11)
Query Neighborhood Hits	67	Target Neighborhood Hits	394	Shared Neighborhood Hits	6
SwissProt Accessions	P39429, O54896	Gene names	Traf2
Domain Architecture
Description	TNF receptor-associated factor 2.

GGA2_HUMAN
θ value	0.62314 (rank : 13)	NC score	0.026771 (rank : 17)
Query Neighborhood Hits	67	Target Neighborhood Hits	114	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UJY4, O14564, Q9NYN2, Q9UPS2	Gene names	GGA2, KIAA1080
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA2 (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (Gamma-adaptin-related protein 2) (VHS domain and ear domain of gamma-adaptin) (Vear).

WRN_MOUSE
θ value	0.62314 (rank : 14)	NC score	0.032912 (rank : 10)
Query Neighborhood Hits	67	Target Neighborhood Hits	295	Shared Neighborhood Hits	7
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

DOK1_MOUSE
θ value	0.813845 (rank : 15)	NC score	0.030361 (rank : 14)
Query Neighborhood Hits	67	Target Neighborhood Hits	82	Shared Neighborhood Hits	3
SwissProt Accessions	P97465, Q9R213	Gene names	Dok1, Dok
Domain Architecture
Description	Docking protein 1 (Downstream of tyrosine kinase 1) (p62(dok)).

G6PD1_MOUSE
θ value	1.06291 (rank : 16)	NC score	0.027920 (rank : 16)
Query Neighborhood Hits	67	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q00612	Gene names	G6pdx, G6pd, G6pd-1
Domain Architecture
Description	Glucose-6-phosphate 1-dehydrogenase X (EC 1.1.1.49) (G6PD).

ZN167_HUMAN
θ value	1.06291 (rank : 17)	NC score	0.001275 (rank : 67)
Query Neighborhood Hits	67	Target Neighborhood Hits	784	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P0L1, Q6WL09, Q96FQ2	Gene names	ZNF167, ZNF448, ZNF64
Domain Architecture	No domain graphic available
Description	Zinc finger protein 167 (Zinc finger protein 64) (Zinc finger protein 448) (ZFP).

CD248_MOUSE
θ value	1.38821 (rank : 18)	NC score	0.016056 (rank : 41)
Query Neighborhood Hits	67	Target Neighborhood Hits	578	Shared Neighborhood Hits	9
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

WASL_HUMAN
θ value	1.81305 (rank : 19)	NC score	0.028134 (rank : 15)
Query Neighborhood Hits	67	Target Neighborhood Hits	312	Shared Neighborhood Hits	8
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

CABC1_MOUSE
θ value	2.36792 (rank : 20)	NC score	0.037314 (rank : 8)
Query Neighborhood Hits	67	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q60936, Q8K0M1	Gene names	Cabc1
Domain Architecture
Description	Chaperone-activity of bc1 complex-like, mitochondrial precursor (Chaperone-ABC1-like).

DFFA_MOUSE
θ value	2.36792 (rank : 21)	NC score	0.030813 (rank : 12)
Query Neighborhood Hits	67	Target Neighborhood Hits	100	Shared Neighborhood Hits	7
SwissProt Accessions	O54786, O54787	Gene names	Dffa, Icad
Domain Architecture	No domain graphic available
Description	DNA fragmentation factor subunit alpha (DNA fragmentation factor 45 kDa subunit) (DFF-45) (Inhibitor of CAD) (ICAD).

NFYC_HUMAN
θ value	2.36792 (rank : 22)	NC score	0.030556 (rank : 13)
Query Neighborhood Hits	67	Target Neighborhood Hits	46	Shared Neighborhood Hits	2
SwissProt Accessions	Q13952, Q5T6K8, Q5T6L1, Q5TZR6, Q92869, Q9HBX1, Q9NXB5, Q9UM67, Q9UML0, Q9UMT7	Gene names	NFYC
Domain Architecture
Description	Nuclear transcription factor Y subunit gamma (Nuclear transcription factor Y subunit C) (NF-YC) (CAAT-box DNA-binding protein subunit C) (Transactivator HSM-1/2).

RPGF2_HUMAN
θ value	2.36792 (rank : 23)	NC score	0.016847 (rank : 38)
Query Neighborhood Hits	67	Target Neighborhood Hits	242	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

SYNE2_HUMAN
θ value	2.36792 (rank : 24)	NC score	0.021424 (rank : 28)
Query Neighborhood Hits	67	Target Neighborhood Hits	1323	Shared Neighborhood Hits	17
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

AL3B2_HUMAN
θ value	3.0926 (rank : 25)	NC score	0.012458 (rank : 52)
Query Neighborhood Hits	67	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	P48448, Q8NAL5, Q96IB2	Gene names	ALDH3B2, ALDH8
Domain Architecture
Description	Aldehyde dehydrogenase 3B2 (EC 1.2.1.5) (Aldehyde dehydrogenase 8).

ALAT2_HUMAN
θ value	3.0926 (rank : 26)	NC score	0.018659 (rank : 32)
Query Neighborhood Hits	67	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TD30, Q8N9E2	Gene names	GPT2, AAT2
Domain Architecture	No domain graphic available
Description	Alanine aminotransferase 2 (EC 2.6.1.2) (ALT2) (Glutamic--pyruvic transaminase 2) (GPT 2) (Glutamic--alanine transaminase 2).

ATF7_MOUSE
θ value	3.0926 (rank : 27)	NC score	0.025185 (rank : 19)
Query Neighborhood Hits	67	Target Neighborhood Hits	286	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R0S1	Gene names	Atf7
Domain Architecture	No domain graphic available
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

CABC1_HUMAN
θ value	3.0926 (rank : 28)	NC score	0.035570 (rank : 9)
Query Neighborhood Hits	67	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NI60, Q8NCJ6	Gene names	CABC1
Domain Architecture
Description	Chaperone-activity of bc1 complex-like, mitochondrial precursor (Chaperone-ABC1-like).

CENPE_HUMAN
θ value	3.0926 (rank : 29)	NC score	0.012626 (rank : 50)
Query Neighborhood Hits	67	Target Neighborhood Hits	2060	Shared Neighborhood Hits	17
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

CND1_MOUSE
θ value	3.0926 (rank : 30)	NC score	0.023876 (rank : 21)
Query Neighborhood Hits	67	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K2Z4, Q8R0F2, Q8R3H0, Q922B7, Q923A3, Q9CS25, Q9CT32	Gene names	Ncapd2, Capd2, Cnap1
Domain Architecture
Description	Condensin complex subunit 1 (Non-SMC condensin I complex subunit D2) (Chromosome condensation-related SMC-associated protein 1) (Chromosome-associated protein D2) (mCAP-D2) (XCAP-D2 homolog).

CP250_MOUSE
θ value	3.0926 (rank : 31)	NC score	0.022313 (rank : 24)
Query Neighborhood Hits	67	Target Neighborhood Hits	1583	Shared Neighborhood Hits	21
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

MYH9_HUMAN
θ value	3.0926 (rank : 32)	NC score	0.012903 (rank : 48)
Query Neighborhood Hits	67	Target Neighborhood Hits	1762	Shared Neighborhood Hits	17
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYH9_MOUSE
θ value	3.0926 (rank : 33)	NC score	0.012795 (rank : 49)
Query Neighborhood Hits	67	Target Neighborhood Hits	1829	Shared Neighborhood Hits	19
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

PDK2_MOUSE
θ value	3.0926 (rank : 34)	NC score	0.017536 (rank : 36)
Query Neighborhood Hits	67	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JK42	Gene names	Pdk2
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 2).

3BP2_HUMAN
θ value	4.03905 (rank : 35)	NC score	0.022162 (rank : 25)
Query Neighborhood Hits	67	Target Neighborhood Hits	296	Shared Neighborhood Hits	11
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

CTR9_MOUSE
θ value	4.03905 (rank : 36)	NC score	0.020386 (rank : 30)
Query Neighborhood Hits	67	Target Neighborhood Hits	427	Shared Neighborhood Hits	12
SwissProt Accessions	Q62018, Q3UFF5, Q3UY40, Q66JX4, Q7TPS6, Q8BND9, Q8BRD1, Q8C9W7, Q8C9Y3, Q8CHI1	Gene names	Ctr9, Kiaa0155, Sh2bp1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) (Tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa) (TPR-containing, SH2-binding phosphoprotein of 150 kDa) (p150TSP).

IF122_HUMAN
θ value	4.03905 (rank : 37)	NC score	0.016440 (rank : 39)
Query Neighborhood Hits	67	Target Neighborhood Hits	244	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HBG6	Gene names	IFT122, WDR10, WDR140
Domain Architecture
Description	Intraflagellar transport 122 homolog (WD repeat protein 10).

PGCA_MOUSE
θ value	4.03905 (rank : 38)	NC score	0.008789 (rank : 61)
Query Neighborhood Hits	67	Target Neighborhood Hits	643	Shared Neighborhood Hits	6
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

SPN90_MOUSE
θ value	4.03905 (rank : 39)	NC score	0.021887 (rank : 26)
Query Neighborhood Hits	67	Target Neighborhood Hits	157	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ESJ4, Q68G72	Gene names	Nckipsd, Spin90, Wasbp
Domain Architecture	No domain graphic available
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (N-WASP-interacting protein, 90kDa) (Wiskott-Aldrich syndrome protein-binding protein WISH) (N-WASP-binding protein).

TIM_MOUSE
θ value	4.03905 (rank : 40)	NC score	0.023632 (rank : 22)
Query Neighborhood Hits	67	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	Q9R1X4, Q63ZX9, Q6P204, Q6PDL4, Q7TPV8, Q8R0Q2, Q9R268, Q9Z0E7	Gene names	Timeless, Tim1, Timeless1
Domain Architecture	No domain graphic available
Description	Timeless homolog (mTim).

GCC2_MOUSE
θ value	5.27518 (rank : 41)	NC score	0.013996 (rank : 47)
Query Neighborhood Hits	67	Target Neighborhood Hits	1619	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

MYH11_MOUSE
θ value	5.27518 (rank : 42)	NC score	0.011967 (rank : 54)
Query Neighborhood Hits	67	Target Neighborhood Hits	1777	Shared Neighborhood Hits	20
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

NASP_HUMAN
θ value	5.27518 (rank : 43)	NC score	0.023475 (rank : 23)
Query Neighborhood Hits	67	Target Neighborhood Hits	709	Shared Neighborhood Hits	16
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

PEX5_HUMAN
θ value	5.27518 (rank : 44)	NC score	0.015017 (rank : 45)
Query Neighborhood Hits	67	Target Neighborhood Hits	92	Shared Neighborhood Hits	3
SwissProt Accessions	P50542, Q15115, Q15266	Gene names	PEX5, PXR1
Domain Architecture
Description	Peroxisomal targeting signal 1 receptor (Peroxisome receptor 1) (Peroxisomal C-terminal targeting signal import receptor) (PTS1-BP) (Peroxin-5) (PTS1 receptor).

WBP11_HUMAN
θ value	5.27518 (rank : 45)	NC score	0.021810 (rank : 27)
Query Neighborhood Hits	67	Target Neighborhood Hits	354	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

ATF7_HUMAN
θ value	6.88961 (rank : 46)	NC score	0.021172 (rank : 29)
Query Neighborhood Hits	67	Target Neighborhood Hits	333	Shared Neighborhood Hits	5
SwissProt Accessions	P17544, Q13814	Gene names	ATF7, ATFA
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

BRD4_HUMAN
θ value	6.88961 (rank : 47)	NC score	0.015417 (rank : 44)
Query Neighborhood Hits	67	Target Neighborhood Hits	851	Shared Neighborhood Hits	19
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

GLDN_MOUSE
θ value	6.88961 (rank : 48)	NC score	0.010120 (rank : 57)
Query Neighborhood Hits	67	Target Neighborhood Hits	155	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BMF8, Q80ZC5	Gene names	Gldn, Crgl2
Domain Architecture	No domain graphic available
Description	Gliomedin (Cancer-related gene liver 2 protein) (CRG-L2).

K0056_HUMAN
θ value	6.88961 (rank : 49)	NC score	0.017264 (rank : 37)
Query Neighborhood Hits	67	Target Neighborhood Hits	107	Shared Neighborhood Hits	5
SwissProt Accessions	P42695	Gene names	KIAA0056
Domain Architecture	No domain graphic available
Description	Protein KIAA0056.

MAP9_HUMAN
θ value	6.88961 (rank : 50)	NC score	0.015553 (rank : 43)
Query Neighborhood Hits	67	Target Neighborhood Hits	518	Shared Neighborhood Hits	10
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

NECD_MOUSE
θ value	6.88961 (rank : 51)	NC score	0.007897 (rank : 62)
Query Neighborhood Hits	67	Target Neighborhood Hits	85	Shared Neighborhood Hits	3
SwissProt Accessions	P25233, Q542W7, Q61951	Gene names	Ndn
Domain Architecture
Description	Necdin.

NR4A2_MOUSE
θ value	6.88961 (rank : 52)	NC score	0.004285 (rank : 66)
Query Neighborhood Hits	67	Target Neighborhood Hits	121	Shared Neighborhood Hits	2
SwissProt Accessions	Q06219, O08690	Gene names	Nr4a2, Nurr1
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (NUR- related factor 1).

PCLO_MOUSE
θ value	6.88961 (rank : 53)	NC score	0.015975 (rank : 42)
Query Neighborhood Hits	67	Target Neighborhood Hits	2275	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PDK2_HUMAN
θ value	6.88961 (rank : 54)	NC score	0.014537 (rank : 46)
Query Neighborhood Hits	67	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q15119, Q9BS05	Gene names	PDK2
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 2).

PER1_MOUSE
θ value	6.88961 (rank : 55)	NC score	0.009153 (rank : 59)
Query Neighborhood Hits	67	Target Neighborhood Hits	235	Shared Neighborhood Hits	2
SwissProt Accessions	O35973	Gene names	Per1, Per, Rigui
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (mPER) (M-Rigui).

RFIP1_HUMAN
θ value	6.88961 (rank : 56)	NC score	0.012473 (rank : 51)
Query Neighborhood Hits	67	Target Neighborhood Hits	236	Shared Neighborhood Hits	4
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

STAG3_HUMAN
θ value	6.88961 (rank : 57)	NC score	0.009679 (rank : 58)
Query Neighborhood Hits	67	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UJ98, Q8NDP3	Gene names	STAG3
Domain Architecture
Description	Cohesin subunit SA-3 (Stromal antigen 3) (Stromalin 3) (SCC3 homolog 3).

TP53B_MOUSE
θ value	6.88961 (rank : 58)	NC score	0.018163 (rank : 33)
Query Neighborhood Hits	67	Target Neighborhood Hits	644	Shared Neighborhood Hits	15
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

CSKI2_MOUSE
θ value	8.99809 (rank : 59)	NC score	0.006200 (rank : 64)
Query Neighborhood Hits	67	Target Neighborhood Hits	812	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

DDEF2_MOUSE
θ value	8.99809 (rank : 60)	NC score	0.007796 (rank : 63)
Query Neighborhood Hits	67	Target Neighborhood Hits	625	Shared Neighborhood Hits	12
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

GLDN_HUMAN
θ value	8.99809 (rank : 61)	NC score	0.008842 (rank : 60)
Query Neighborhood Hits	67	Target Neighborhood Hits	159	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZMI3, Q6UXZ7, Q7Z359	Gene names	GLDN, COLM
Domain Architecture	No domain graphic available
Description	Gliomedin.

HAP1_HUMAN
θ value	8.99809 (rank : 62)	NC score	0.016234 (rank : 40)
Query Neighborhood Hits	67	Target Neighborhood Hits	606	Shared Neighborhood Hits	14
SwissProt Accessions	P54257, O75358, Q9H4G3, Q9HA98, Q9NY90	Gene names	HAP1, HLP1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1) (Neuroan 1).

LYST_MOUSE
θ value	8.99809 (rank : 63)	NC score	0.010529 (rank : 56)
Query Neighborhood Hits	67	Target Neighborhood Hits	286	Shared Neighborhood Hits	5
SwissProt Accessions	P97412, Q62403, Q8VBS6	Gene names	Lyst, Bg, Chs1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige protein) (CHS1 homolog).

NALP2_HUMAN
θ value	8.99809 (rank : 64)	NC score	0.005648 (rank : 65)
Query Neighborhood Hits	67	Target Neighborhood Hits	65	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NX02, Q53FL5, Q59G09, Q8IXT0, Q9BVN5, Q9H6G6, Q9HAV9, Q9NWK3	Gene names	NALP2, NBS1, PAN1, PYPAF2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 2 (PYRIN domain and NACHT domain-containing protein 1) (PYRIN-containing APAF1-like protein 2) (Nucleotide-binding site protein 1).

RCOR2_HUMAN
θ value	8.99809 (rank : 65)	NC score	0.011925 (rank : 55)
Query Neighborhood Hits	67	Target Neighborhood Hits	114	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IZ40, Q96FP3	Gene names	RCOR2
Domain Architecture	No domain graphic available
Description	REST corepressor 2.

RCOR2_MOUSE
θ value	8.99809 (rank : 66)	NC score	0.011969 (rank : 53)
Query Neighborhood Hits	67	Target Neighborhood Hits	107	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C796, Q9JMK4	Gene names	Rcor2
Domain Architecture	No domain graphic available
Description	REST corepressor 2 (M-CoREST).

WBP11_MOUSE
θ value	8.99809 (rank : 67)	NC score	0.017788 (rank : 34)
Query Neighborhood Hits	67	Target Neighborhood Hits	362	Shared Neighborhood Hits	8
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

Hits sorted by NC score

ESPL1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	67	Target Neighborhood Hits	67	Shared Neighborhood Hits	67
SwissProt Accessions	P60330	Gene names	Espl1, Esp1, Kiaa0165
Domain Architecture
Description	Separin (EC 3.4.22.49) (Separase) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein).

ESPL1_HUMAN
NC score	0.972047 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	67	Target Neighborhood Hits	95	Shared Neighborhood Hits	7
SwissProt Accessions	Q14674	Gene names	ESPL1, ESP1, KIAA0165
Domain Architecture
Description	Separin (EC 3.4.22.49) (Separase) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein).

BTBDC_HUMAN
NC score	0.092385 (rank : 3)	θ value	0.0193708 (rank : 4)
Query Neighborhood Hits	67	Target Neighborhood Hits	248	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

MDC1_HUMAN
NC score	0.068366 (rank : 4)	θ value	5.44631e-05 (rank : 3)
Query Neighborhood Hits	67	Target Neighborhood Hits	1446	Shared Neighborhood Hits	26
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

ZN395_HUMAN
NC score	0.062745 (rank : 5)	θ value	0.365318 (rank : 10)
Query Neighborhood Hits	67	Target Neighborhood Hits	64	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H8N7, Q6F6H2, Q9BY72, Q9NPB2, Q9NS57, Q9NS58, Q9NS59	Gene names	ZNF395, HDBP2, PBF
Domain Architecture	No domain graphic available
Description	Zinc finger protein 395 (Papillomavirus-binding factor) (Papillomavirus regulatory factor 1) (PRF-1) (Huntington disease gene regulatory region-binding protein 2) (HDBP-2) (HD gene regulatory region-binding protein 2) (HD-regulating factor 2) (HDRF-2).

ENL_HUMAN
NC score	0.054674 (rank : 6)	θ value	0.279714 (rank : 9)
Query Neighborhood Hits	67	Target Neighborhood Hits	305	Shared Neighborhood Hits	7
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

UBP31_HUMAN
NC score	0.039537 (rank : 7)	θ value	0.0330416 (rank : 6)
Query Neighborhood Hits	67	Target Neighborhood Hits	293	Shared Neighborhood Hits	5
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

CABC1_MOUSE
NC score	0.037314 (rank : 8)	θ value	2.36792 (rank : 20)
Query Neighborhood Hits	67	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q60936, Q8K0M1	Gene names	Cabc1
Domain Architecture
Description	Chaperone-activity of bc1 complex-like, mitochondrial precursor (Chaperone-ABC1-like).

CABC1_HUMAN
NC score	0.035570 (rank : 9)	θ value	3.0926 (rank : 28)
Query Neighborhood Hits	67	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NI60, Q8NCJ6	Gene names	CABC1
Domain Architecture
Description	Chaperone-activity of bc1 complex-like, mitochondrial precursor (Chaperone-ABC1-like).

WRN_MOUSE
NC score	0.032912 (rank : 10)	θ value	0.62314 (rank : 14)
Query Neighborhood Hits	67	Target Neighborhood Hits	295	Shared Neighborhood Hits	7
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

TRAF2_MOUSE
NC score	0.031188 (rank : 11)	θ value	0.47712 (rank : 12)
Query Neighborhood Hits	67	Target Neighborhood Hits	394	Shared Neighborhood Hits	6
SwissProt Accessions	P39429, O54896	Gene names	Traf2
Domain Architecture
Description	TNF receptor-associated factor 2.

DFFA_MOUSE
NC score	0.030813 (rank : 12)	θ value	2.36792 (rank : 21)
Query Neighborhood Hits	67	Target Neighborhood Hits	100	Shared Neighborhood Hits	7
SwissProt Accessions	O54786, O54787	Gene names	Dffa, Icad
Domain Architecture	No domain graphic available
Description	DNA fragmentation factor subunit alpha (DNA fragmentation factor 45 kDa subunit) (DFF-45) (Inhibitor of CAD) (ICAD).

NFYC_HUMAN
NC score	0.030556 (rank : 13)	θ value	2.36792 (rank : 22)
Query Neighborhood Hits	67	Target Neighborhood Hits	46	Shared Neighborhood Hits	2
SwissProt Accessions	Q13952, Q5T6K8, Q5T6L1, Q5TZR6, Q92869, Q9HBX1, Q9NXB5, Q9UM67, Q9UML0, Q9UMT7	Gene names	NFYC
Domain Architecture
Description	Nuclear transcription factor Y subunit gamma (Nuclear transcription factor Y subunit C) (NF-YC) (CAAT-box DNA-binding protein subunit C) (Transactivator HSM-1/2).

DOK1_MOUSE
NC score	0.030361 (rank : 14)	θ value	0.813845 (rank : 15)
Query Neighborhood Hits	67	Target Neighborhood Hits	82	Shared Neighborhood Hits	3
SwissProt Accessions	P97465, Q9R213	Gene names	Dok1, Dok
Domain Architecture
Description	Docking protein 1 (Downstream of tyrosine kinase 1) (p62(dok)).

WASL_HUMAN
NC score	0.028134 (rank : 15)	θ value	1.81305 (rank : 19)
Query Neighborhood Hits	67	Target Neighborhood Hits	312	Shared Neighborhood Hits	8
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

G6PD1_MOUSE
NC score	0.027920 (rank : 16)	θ value	1.06291 (rank : 16)
Query Neighborhood Hits	67	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q00612	Gene names	G6pdx, G6pd, G6pd-1
Domain Architecture
Description	Glucose-6-phosphate 1-dehydrogenase X (EC 1.1.1.49) (G6PD).

GGA2_HUMAN
NC score	0.026771 (rank : 17)	θ value	0.62314 (rank : 13)
Query Neighborhood Hits	67	Target Neighborhood Hits	114	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UJY4, O14564, Q9NYN2, Q9UPS2	Gene names	GGA2, KIAA1080
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA2 (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (Gamma-adaptin-related protein 2) (VHS domain and ear domain of gamma-adaptin) (Vear).

AKAP9_HUMAN
NC score	0.026525 (rank : 18)	θ value	0.47712 (rank : 11)
Query Neighborhood Hits	67	Target Neighborhood Hits	1710	Shared Neighborhood Hits	16
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

ATF7_MOUSE
NC score	0.025185 (rank : 19)	θ value	3.0926 (rank : 27)
Query Neighborhood Hits	67	Target Neighborhood Hits	286	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R0S1	Gene names	Atf7
Domain Architecture	No domain graphic available
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

CP250_HUMAN
NC score	0.024382 (rank : 20)	θ value	0.0736092 (rank : 7)
Query Neighborhood Hits	67	Target Neighborhood Hits	1805	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

CND1_MOUSE
NC score	0.023876 (rank : 21)	θ value	3.0926 (rank : 30)
Query Neighborhood Hits	67	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K2Z4, Q8R0F2, Q8R3H0, Q922B7, Q923A3, Q9CS25, Q9CT32	Gene names	Ncapd2, Capd2, Cnap1
Domain Architecture
Description	Condensin complex subunit 1 (Non-SMC condensin I complex subunit D2) (Chromosome condensation-related SMC-associated protein 1) (Chromosome-associated protein D2) (mCAP-D2) (XCAP-D2 homolog).

TIM_MOUSE
NC score	0.023632 (rank : 22)	θ value	4.03905 (rank : 40)
Query Neighborhood Hits	67	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	Q9R1X4, Q63ZX9, Q6P204, Q6PDL4, Q7TPV8, Q8R0Q2, Q9R268, Q9Z0E7	Gene names	Timeless, Tim1, Timeless1
Domain Architecture	No domain graphic available
Description	Timeless homolog (mTim).

NASP_HUMAN
NC score	0.023475 (rank : 23)	θ value	5.27518 (rank : 43)
Query Neighborhood Hits	67	Target Neighborhood Hits	709	Shared Neighborhood Hits	16
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

CP250_MOUSE
NC score	0.022313 (rank : 24)	θ value	3.0926 (rank : 31)
Query Neighborhood Hits	67	Target Neighborhood Hits	1583	Shared Neighborhood Hits	21
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

3BP2_HUMAN
NC score	0.022162 (rank : 25)	θ value	4.03905 (rank : 35)
Query Neighborhood Hits	67	Target Neighborhood Hits	296	Shared Neighborhood Hits	11
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

SPN90_MOUSE
NC score	0.021887 (rank : 26)	θ value	4.03905 (rank : 39)
Query Neighborhood Hits	67	Target Neighborhood Hits	157	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ESJ4, Q68G72	Gene names	Nckipsd, Spin90, Wasbp
Domain Architecture	No domain graphic available
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (N-WASP-interacting protein, 90kDa) (Wiskott-Aldrich syndrome protein-binding protein WISH) (N-WASP-binding protein).

WBP11_HUMAN
NC score	0.021810 (rank : 27)	θ value	5.27518 (rank : 45)
Query Neighborhood Hits	67	Target Neighborhood Hits	354	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

SYNE2_HUMAN
NC score	0.021424 (rank : 28)	θ value	2.36792 (rank : 24)
Query Neighborhood Hits	67	Target Neighborhood Hits	1323	Shared Neighborhood Hits	17
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

ATF7_HUMAN
NC score	0.021172 (rank : 29)	θ value	6.88961 (rank : 46)
Query Neighborhood Hits	67	Target Neighborhood Hits	333	Shared Neighborhood Hits	5
SwissProt Accessions	P17544, Q13814	Gene names	ATF7, ATFA
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

CTR9_MOUSE
NC score	0.020386 (rank : 30)	θ value	4.03905 (rank : 36)
Query Neighborhood Hits	67	Target Neighborhood Hits	427	Shared Neighborhood Hits	12
SwissProt Accessions	Q62018, Q3UFF5, Q3UY40, Q66JX4, Q7TPS6, Q8BND9, Q8BRD1, Q8C9W7, Q8C9Y3, Q8CHI1	Gene names	Ctr9, Kiaa0155, Sh2bp1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) (Tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa) (TPR-containing, SH2-binding phosphoprotein of 150 kDa) (p150TSP).

SPEG_MOUSE
NC score	0.019052 (rank : 31)	θ value	0.0252991 (rank : 5)
Query Neighborhood Hits	67	Target Neighborhood Hits	1959	Shared Neighborhood Hits	13
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

ALAT2_HUMAN
NC score	0.018659 (rank : 32)	θ value	3.0926 (rank : 26)
Query Neighborhood Hits	67	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TD30, Q8N9E2	Gene names	GPT2, AAT2
Domain Architecture	No domain graphic available
Description	Alanine aminotransferase 2 (EC 2.6.1.2) (ALT2) (Glutamic--pyruvic transaminase 2) (GPT 2) (Glutamic--alanine transaminase 2).

TP53B_MOUSE
NC score	0.018163 (rank : 33)	θ value	6.88961 (rank : 58)
Query Neighborhood Hits	67	Target Neighborhood Hits	644	Shared Neighborhood Hits	15
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

WBP11_MOUSE
NC score	0.017788 (rank : 34)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	67	Target Neighborhood Hits	362	Shared Neighborhood Hits	8
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

SPEG_HUMAN
NC score	0.017680 (rank : 35)	θ value	0.125558 (rank : 8)
Query Neighborhood Hits	67	Target Neighborhood Hits	1762	Shared Neighborhood Hits	11
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

PDK2_MOUSE
NC score	0.017536 (rank : 36)	θ value	3.0926 (rank : 34)
Query Neighborhood Hits	67	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JK42	Gene names	Pdk2
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 2).

K0056_HUMAN
NC score	0.017264 (rank : 37)	θ value	6.88961 (rank : 49)
Query Neighborhood Hits	67	Target Neighborhood Hits	107	Shared Neighborhood Hits	5
SwissProt Accessions	P42695	Gene names	KIAA0056
Domain Architecture	No domain graphic available
Description	Protein KIAA0056.

RPGF2_HUMAN
NC score	0.016847 (rank : 38)	θ value	2.36792 (rank : 23)
Query Neighborhood Hits	67	Target Neighborhood Hits	242	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

IF122_HUMAN
NC score	0.016440 (rank : 39)	θ value	4.03905 (rank : 37)
Query Neighborhood Hits	67	Target Neighborhood Hits	244	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HBG6	Gene names	IFT122, WDR10, WDR140
Domain Architecture
Description	Intraflagellar transport 122 homolog (WD repeat protein 10).

HAP1_HUMAN
NC score	0.016234 (rank : 40)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	67	Target Neighborhood Hits	606	Shared Neighborhood Hits	14
SwissProt Accessions	P54257, O75358, Q9H4G3, Q9HA98, Q9NY90	Gene names	HAP1, HLP1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1) (Neuroan 1).

CD248_MOUSE
NC score	0.016056 (rank : 41)	θ value	1.38821 (rank : 18)
Query Neighborhood Hits	67	Target Neighborhood Hits	578	Shared Neighborhood Hits	9
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

PCLO_MOUSE
NC score	0.015975 (rank : 42)	θ value	6.88961 (rank : 53)
Query Neighborhood Hits	67	Target Neighborhood Hits	2275	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

MAP9_HUMAN
NC score	0.015553 (rank : 43)	θ value	6.88961 (rank : 50)
Query Neighborhood Hits	67	Target Neighborhood Hits	518	Shared Neighborhood Hits	10
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

BRD4_HUMAN
NC score	0.015417 (rank : 44)	θ value	6.88961 (rank : 47)
Query Neighborhood Hits	67	Target Neighborhood Hits	851	Shared Neighborhood Hits	19
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

PEX5_HUMAN
NC score	0.015017 (rank : 45)	θ value	5.27518 (rank : 44)
Query Neighborhood Hits	67	Target Neighborhood Hits	92	Shared Neighborhood Hits	3
SwissProt Accessions	P50542, Q15115, Q15266	Gene names	PEX5, PXR1
Domain Architecture
Description	Peroxisomal targeting signal 1 receptor (Peroxisome receptor 1) (Peroxisomal C-terminal targeting signal import receptor) (PTS1-BP) (Peroxin-5) (PTS1 receptor).

PDK2_HUMAN
NC score	0.014537 (rank : 46)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	67	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q15119, Q9BS05	Gene names	PDK2
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 2).

GCC2_MOUSE
NC score	0.013996 (rank : 47)	θ value	5.27518 (rank : 41)
Query Neighborhood Hits	67	Target Neighborhood Hits	1619	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

MYH9_HUMAN
NC score	0.012903 (rank : 48)	θ value	3.0926 (rank : 32)
Query Neighborhood Hits	67	Target Neighborhood Hits	1762	Shared Neighborhood Hits	17
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYH9_MOUSE
NC score	0.012795 (rank : 49)	θ value	3.0926 (rank : 33)
Query Neighborhood Hits	67	Target Neighborhood Hits	1829	Shared Neighborhood Hits	19
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

CENPE_HUMAN
NC score	0.012626 (rank : 50)	θ value	3.0926 (rank : 29)
Query Neighborhood Hits	67	Target Neighborhood Hits	2060	Shared Neighborhood Hits	17
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

RFIP1_HUMAN
NC score	0.012473 (rank : 51)	θ value	6.88961 (rank : 56)
Query Neighborhood Hits	67	Target Neighborhood Hits	236	Shared Neighborhood Hits	4
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

AL3B2_HUMAN
NC score	0.012458 (rank : 52)	θ value	3.0926 (rank : 25)
Query Neighborhood Hits	67	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	P48448, Q8NAL5, Q96IB2	Gene names	ALDH3B2, ALDH8
Domain Architecture
Description	Aldehyde dehydrogenase 3B2 (EC 1.2.1.5) (Aldehyde dehydrogenase 8).

RCOR2_MOUSE
NC score	0.011969 (rank : 53)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	67	Target Neighborhood Hits	107	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C796, Q9JMK4	Gene names	Rcor2
Domain Architecture	No domain graphic available
Description	REST corepressor 2 (M-CoREST).

MYH11_MOUSE
NC score	0.011967 (rank : 54)	θ value	5.27518 (rank : 42)
Query Neighborhood Hits	67	Target Neighborhood Hits	1777	Shared Neighborhood Hits	20
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

RCOR2_HUMAN
NC score	0.011925 (rank : 55)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	67	Target Neighborhood Hits	114	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IZ40, Q96FP3	Gene names	RCOR2
Domain Architecture	No domain graphic available
Description	REST corepressor 2.

LYST_MOUSE
NC score	0.010529 (rank : 56)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	67	Target Neighborhood Hits	286	Shared Neighborhood Hits	5
SwissProt Accessions	P97412, Q62403, Q8VBS6	Gene names	Lyst, Bg, Chs1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige protein) (CHS1 homolog).

GLDN_MOUSE
NC score	0.010120 (rank : 57)	θ value	6.88961 (rank : 48)
Query Neighborhood Hits	67	Target Neighborhood Hits	155	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BMF8, Q80ZC5	Gene names	Gldn, Crgl2
Domain Architecture	No domain graphic available
Description	Gliomedin (Cancer-related gene liver 2 protein) (CRG-L2).

STAG3_HUMAN
NC score	0.009679 (rank : 58)	θ value	6.88961 (rank : 57)
Query Neighborhood Hits	67	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UJ98, Q8NDP3	Gene names	STAG3
Domain Architecture
Description	Cohesin subunit SA-3 (Stromal antigen 3) (Stromalin 3) (SCC3 homolog 3).

PER1_MOUSE
NC score	0.009153 (rank : 59)	θ value	6.88961 (rank : 55)
Query Neighborhood Hits	67	Target Neighborhood Hits	235	Shared Neighborhood Hits	2
SwissProt Accessions	O35973	Gene names	Per1, Per, Rigui
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (mPER) (M-Rigui).

GLDN_HUMAN
NC score	0.008842 (rank : 60)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	67	Target Neighborhood Hits	159	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZMI3, Q6UXZ7, Q7Z359	Gene names	GLDN, COLM
Domain Architecture	No domain graphic available
Description	Gliomedin.

PGCA_MOUSE
NC score	0.008789 (rank : 61)	θ value	4.03905 (rank : 38)
Query Neighborhood Hits	67	Target Neighborhood Hits	643	Shared Neighborhood Hits	6
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

NECD_MOUSE
NC score	0.007897 (rank : 62)	θ value	6.88961 (rank : 51)
Query Neighborhood Hits	67	Target Neighborhood Hits	85	Shared Neighborhood Hits	3
SwissProt Accessions	P25233, Q542W7, Q61951	Gene names	Ndn
Domain Architecture
Description	Necdin.

DDEF2_MOUSE
NC score	0.007796 (rank : 63)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	67	Target Neighborhood Hits	625	Shared Neighborhood Hits	12
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

CSKI2_MOUSE
NC score	0.006200 (rank : 64)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	67	Target Neighborhood Hits	812	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

NALP2_HUMAN
NC score	0.005648 (rank : 65)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	67	Target Neighborhood Hits	65	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NX02, Q53FL5, Q59G09, Q8IXT0, Q9BVN5, Q9H6G6, Q9HAV9, Q9NWK3	Gene names	NALP2, NBS1, PAN1, PYPAF2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 2 (PYRIN domain and NACHT domain-containing protein 1) (PYRIN-containing APAF1-like protein 2) (Nucleotide-binding site protein 1).

NR4A2_MOUSE
NC score	0.004285 (rank : 66)	θ value	6.88961 (rank : 52)
Query Neighborhood Hits	67	Target Neighborhood Hits	121	Shared Neighborhood Hits	2
SwissProt Accessions	Q06219, O08690	Gene names	Nr4a2, Nurr1
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (NUR- related factor 1).

ZN167_HUMAN
NC score	0.001275 (rank : 67)	θ value	1.06291 (rank : 17)
Query Neighborhood Hits	67	Target Neighborhood Hits	784	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P0L1, Q6WL09, Q96FQ2	Gene names	ZNF167, ZNF448, ZNF64
Domain Architecture	No domain graphic available
Description	Zinc finger protein 167 (Zinc finger protein 64) (Zinc finger protein 448) (ZFP).