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Network neighborhood for query Sequence : ALAT2_HUMAN

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ALAT2_HUMAN
SwissProt Accessions	Q8TD30, Q8N9E2	Gene names	GPT2, AAT2
Domain Architecture	No domain graphic available
Description	Alanine aminotransferase 2 (EC 2.6.1.2) (ALT2) (Glutamic--pyruvic transaminase 2) (GPT 2) (Glutamic--alanine transaminase 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ALAT1_HUMAN
θ value	0 (rank : 1)	NC score	0.994613 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	P24298, P78398, Q93076	Gene names	GPT, AAT1, GPT1
Domain Architecture
Description	Alanine aminotransferase 1 (EC 2.6.1.2) (ALT1) (Glutamic--pyruvic transaminase 1) (GPT 1) (Glutamic--alanine transaminase 1).

ALAT1_MOUSE
θ value	0 (rank : 2)	NC score	0.995003 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	Q8QZR5	Gene names	Gpt, Gpt1
Domain Architecture
Description	Alanine aminotransferase 1 (EC 2.6.1.2) (ALT1) (Glutamic--pyruvic transaminase 1) (GPT 1) (Glutamic--alanine transaminase 1).

ALAT2_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q8TD30, Q8N9E2	Gene names	GPT2, AAT2
Domain Architecture	No domain graphic available
Description	Alanine aminotransferase 2 (EC 2.6.1.2) (ALT2) (Glutamic--pyruvic transaminase 2) (GPT 2) (Glutamic--alanine transaminase 2).

ALAT2_MOUSE
θ value	0 (rank : 4)	NC score	0.999126 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	11	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BGT5, Q8BVY7, Q8K1J3	Gene names	Gpt2, Aat2
Domain Architecture	No domain graphic available
Description	Alanine aminotransferase 2 (EC 2.6.1.2) (ALT2) (Glutamic--pyruvic transaminase 2) (GPT 2) (Glutamic--alanine transaminase 2).

ATTY_MOUSE
θ value	2.5182e-18 (rank : 5)	NC score	0.587857 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	Q8QZR1, Q3UER7, Q8BTI1	Gene names	Tat
Domain Architecture
Description	Tyrosine aminotransferase (EC 2.6.1.5) (L-tyrosine:2-oxoglutarate aminotransferase) (TAT).

ATTY_HUMAN
θ value	1.52774e-15 (rank : 6)	NC score	0.568723 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	P17735	Gene names	TAT
Domain Architecture
Description	Tyrosine aminotransferase (EC 2.6.1.5) (L-tyrosine:2-oxoglutarate aminotransferase) (TAT).

KAT1_MOUSE
θ value	0.00035302 (rank : 7)	NC score	0.314174 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BTY1, Q8BY27	Gene names	Ccbl1, Kat
Domain Architecture
Description	Kynurenine--oxoglutarate transaminase 1 (EC 2.6.1.7) (Kynurenine-- oxoglutarate transaminase I) (Kynurenine aminotransferase I) (KATI) (Glutamine--phenylpyruvate transaminase) (EC 2.6.1.64) (Glutamine transaminase K) (GTK) (Cysteine-S-conjugate beta-lyase) (EC 4.4.1.13).

KAT1_HUMAN
θ value	0.0330416 (rank : 8)	NC score	0.278810 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	Q16773, Q8N191	Gene names	CCBL1
Domain Architecture
Description	Kynurenine--oxoglutarate transaminase 1 (EC 2.6.1.7) (Kynurenine-- oxoglutarate transaminase I) (Kynurenine aminotransferase I) (KATI) (Glutamine--phenylpyruvate transaminase) (EC 2.6.1.64) (Glutamine transaminase K) (GTK) (Cysteine-S-conjugate beta-lyase) (EC 4.4.1.13).

ESPL1_MOUSE
θ value	3.0926 (rank : 9)	NC score	0.018659 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	67	Shared Neighborhood Hits	2
SwissProt Accessions	P60330	Gene names	Espl1, Esp1, Kiaa0165
Domain Architecture
Description	Separin (EC 3.4.22.49) (Separase) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein).

ACOT2_HUMAN
θ value	4.03905 (rank : 10)	NC score	0.013907 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	P49753, Q9NUX4	Gene names	ACOT2, PTE2, PTE2A
Domain Architecture
Description	Acyl-coenzyme A thioesterase 2 (EC 3.1.2.2) (Acyl-CoA thioesterase 2) (Peroxisomal acyl-coenzyme A thioester hydrolase 2a) (Peroxisomal long-chain acyl-coA thioesterase 2) (ZAP128) (CTE-Ia).

CH60_MOUSE
θ value	4.03905 (rank : 11)	NC score	0.015103 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	43	Shared Neighborhood Hits	2
SwissProt Accessions	P63038, P19226, P19227, P97602	Gene names	Hspd1, Hsp60
Domain Architecture	No domain graphic available
Description	60 kDa heat shock protein, mitochondrial precursor (Hsp60) (60 kDa chaperonin) (CPN60) (Heat shock protein 60) (HSP-60) (Mitochondrial matrix protein P1) (HSP-65).

ACOT1_HUMAN
θ value	5.27518 (rank : 12)	NC score	0.013007 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q86TX2, Q3I5F9	Gene names	ACOT1, CTE1
Domain Architecture	No domain graphic available
Description	Acyl-coenzyme A thioesterase 1 (EC 3.1.2.2) (Acyl-CoA thioesterase 1) (Inducible cytosolic acyl-coenzyme A thioester hydrolase) (Long chain acyl-CoA thioester hydrolase) (Long chain acyl-CoA hydrolase) (CTE-I) (CTE-Ib).

UACA_HUMAN
θ value	6.88961 (rank : 13)	NC score	0.002263 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	1622	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

NGAP_HUMAN
θ value	8.99809 (rank : 14)	NC score	0.005261 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	517	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UJF2, O95174, Q5TFU9	Gene names	RASAL2, NGAP
Domain Architecture
Description	Ras GTPase-activating protein nGAP (RAS protein activator-like 1).

Hits sorted by NC score

ALAT2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q8TD30, Q8N9E2	Gene names	GPT2, AAT2
Domain Architecture	No domain graphic available
Description	Alanine aminotransferase 2 (EC 2.6.1.2) (ALT2) (Glutamic--pyruvic transaminase 2) (GPT 2) (Glutamic--alanine transaminase 2).

ALAT2_MOUSE
NC score	0.999126 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	11	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BGT5, Q8BVY7, Q8K1J3	Gene names	Gpt2, Aat2
Domain Architecture	No domain graphic available
Description	Alanine aminotransferase 2 (EC 2.6.1.2) (ALT2) (Glutamic--pyruvic transaminase 2) (GPT 2) (Glutamic--alanine transaminase 2).

ALAT1_MOUSE
NC score	0.995003 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	Q8QZR5	Gene names	Gpt, Gpt1
Domain Architecture
Description	Alanine aminotransferase 1 (EC 2.6.1.2) (ALT1) (Glutamic--pyruvic transaminase 1) (GPT 1) (Glutamic--alanine transaminase 1).

ALAT1_HUMAN
NC score	0.994613 (rank : 4)	θ value	0 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	P24298, P78398, Q93076	Gene names	GPT, AAT1, GPT1
Domain Architecture
Description	Alanine aminotransferase 1 (EC 2.6.1.2) (ALT1) (Glutamic--pyruvic transaminase 1) (GPT 1) (Glutamic--alanine transaminase 1).

ATTY_MOUSE
NC score	0.587857 (rank : 5)	θ value	2.5182e-18 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	Q8QZR1, Q3UER7, Q8BTI1	Gene names	Tat
Domain Architecture
Description	Tyrosine aminotransferase (EC 2.6.1.5) (L-tyrosine:2-oxoglutarate aminotransferase) (TAT).

ATTY_HUMAN
NC score	0.568723 (rank : 6)	θ value	1.52774e-15 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	P17735	Gene names	TAT
Domain Architecture
Description	Tyrosine aminotransferase (EC 2.6.1.5) (L-tyrosine:2-oxoglutarate aminotransferase) (TAT).

KAT1_MOUSE
NC score	0.314174 (rank : 7)	θ value	0.00035302 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BTY1, Q8BY27	Gene names	Ccbl1, Kat
Domain Architecture
Description	Kynurenine--oxoglutarate transaminase 1 (EC 2.6.1.7) (Kynurenine-- oxoglutarate transaminase I) (Kynurenine aminotransferase I) (KATI) (Glutamine--phenylpyruvate transaminase) (EC 2.6.1.64) (Glutamine transaminase K) (GTK) (Cysteine-S-conjugate beta-lyase) (EC 4.4.1.13).

KAT1_HUMAN
NC score	0.278810 (rank : 8)	θ value	0.0330416 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	Q16773, Q8N191	Gene names	CCBL1
Domain Architecture
Description	Kynurenine--oxoglutarate transaminase 1 (EC 2.6.1.7) (Kynurenine-- oxoglutarate transaminase I) (Kynurenine aminotransferase I) (KATI) (Glutamine--phenylpyruvate transaminase) (EC 2.6.1.64) (Glutamine transaminase K) (GTK) (Cysteine-S-conjugate beta-lyase) (EC 4.4.1.13).

ESPL1_MOUSE
NC score	0.018659 (rank : 9)	θ value	3.0926 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	67	Shared Neighborhood Hits	2
SwissProt Accessions	P60330	Gene names	Espl1, Esp1, Kiaa0165
Domain Architecture
Description	Separin (EC 3.4.22.49) (Separase) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein).

CH60_MOUSE
NC score	0.015103 (rank : 10)	θ value	4.03905 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	43	Shared Neighborhood Hits	2
SwissProt Accessions	P63038, P19226, P19227, P97602	Gene names	Hspd1, Hsp60
Domain Architecture	No domain graphic available
Description	60 kDa heat shock protein, mitochondrial precursor (Hsp60) (60 kDa chaperonin) (CPN60) (Heat shock protein 60) (HSP-60) (Mitochondrial matrix protein P1) (HSP-65).

ACOT2_HUMAN
NC score	0.013907 (rank : 11)	θ value	4.03905 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	P49753, Q9NUX4	Gene names	ACOT2, PTE2, PTE2A
Domain Architecture
Description	Acyl-coenzyme A thioesterase 2 (EC 3.1.2.2) (Acyl-CoA thioesterase 2) (Peroxisomal acyl-coenzyme A thioester hydrolase 2a) (Peroxisomal long-chain acyl-coA thioesterase 2) (ZAP128) (CTE-Ia).

ACOT1_HUMAN
NC score	0.013007 (rank : 12)	θ value	5.27518 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q86TX2, Q3I5F9	Gene names	ACOT1, CTE1
Domain Architecture	No domain graphic available
Description	Acyl-coenzyme A thioesterase 1 (EC 3.1.2.2) (Acyl-CoA thioesterase 1) (Inducible cytosolic acyl-coenzyme A thioester hydrolase) (Long chain acyl-CoA thioester hydrolase) (Long chain acyl-CoA hydrolase) (CTE-I) (CTE-Ib).

NGAP_HUMAN
NC score	0.005261 (rank : 13)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	517	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UJF2, O95174, Q5TFU9	Gene names	RASAL2, NGAP
Domain Architecture
Description	Ras GTPase-activating protein nGAP (RAS protein activator-like 1).

UACA_HUMAN
NC score	0.002263 (rank : 14)	θ value	6.88961 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	1622	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.