Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : SPEG_MOUSE

For an explanation of this page, click here

SPEG_MOUSE
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SPEG_HUMAN
θ value	0 (rank : 1)	NC score	0.986780 (rank : 2)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1762	Shared Neighborhood Hits	1436
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SPEG_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1959	Shared Neighborhood Hits	1959
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

OBSCN_HUMAN
θ value	5.85632e-100 (rank : 3)	NC score	0.941840 (rank : 5)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1931	Shared Neighborhood Hits	1282
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

TITIN_HUMAN
θ value	2.18062e-54 (rank : 4)	NC score	0.889508 (rank : 7)
Query Neighborhood Hits	1959	Target Neighborhood Hits	2923	Shared Neighborhood Hits	1341
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

DAPK2_HUMAN
θ value	1.11993e-50 (rank : 5)	NC score	0.882671 (rank : 8)
Query Neighborhood Hits	1959	Target Neighborhood Hits	832	Shared Neighborhood Hits	811
SwissProt Accessions	Q9UIK4, O75892	Gene names	DAPK2
Domain Architecture
Description	Death-associated protein kinase 2 (EC 2.7.11.1) (DAP kinase 2) (DAP- kinase-related protein 1) (DRP-1).

DAPK2_MOUSE
θ value	1.46268e-50 (rank : 6)	NC score	0.882101 (rank : 9)
Query Neighborhood Hits	1959	Target Neighborhood Hits	834	Shared Neighborhood Hits	814
SwissProt Accessions	Q8VDF3, O88861, Q9QYM4	Gene names	Dapk2
Domain Architecture
Description	Death-associated protein kinase 2 (EC 2.7.11.1) (DAP kinase 2) (DAP- kinase-related protein 1) (DRP-1).

MYLK_MOUSE
θ value	3.2585e-50 (rank : 7)	NC score	0.951002 (rank : 3)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1489	Shared Neighborhood Hits	1180
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

DAPK3_MOUSE
θ value	5.55816e-50 (rank : 8)	NC score	0.881167 (rank : 11)
Query Neighborhood Hits	1959	Target Neighborhood Hits	843	Shared Neighborhood Hits	810
SwissProt Accessions	O54784	Gene names	Dapk3, Zipk
Domain Architecture
Description	Death-associated protein kinase 3 (EC 2.7.11.1) (DAP kinase 3) (DAP- like kinase) (Dlk) (ZIP-kinase).

MYLK_HUMAN
θ value	5.55816e-50 (rank : 9)	NC score	0.950171 (rank : 4)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1328	Shared Neighborhood Hits	1097
SwissProt Accessions	Q15746, O95796, O95797, O95798, O95799, Q14844, Q16794, Q5MY99, Q5MYA0, Q7Z4J0, Q9C0L5, Q9UBG5, Q9UIT9	Gene names	MYLK, MLCK
Domain Architecture
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

DAPK1_HUMAN
θ value	7.25919e-50 (rank : 10)	NC score	0.795941 (rank : 460)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1130	Shared Neighborhood Hits	836
SwissProt Accessions	P53355, Q9BTL8	Gene names	DAPK1, DAPK
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

DAPK1_MOUSE
θ value	1.23823e-49 (rank : 11)	NC score	0.791733 (rank : 468)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1138	Shared Neighborhood Hits	836
SwissProt Accessions	Q80YE7, Q80YE6, Q8R341, Q8VDN6, Q9CSD4, Q9JJP7	Gene names	Dapk1
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

DAPK3_HUMAN
θ value	1.85029e-45 (rank : 12)	NC score	0.879936 (rank : 12)
Query Neighborhood Hits	1959	Target Neighborhood Hits	945	Shared Neighborhood Hits	816
SwissProt Accessions	O43293	Gene names	DAPK3, ZIPK
Domain Architecture
Description	Death-associated protein kinase 3 (EC 2.7.11.1) (DAP kinase 3) (DAP- like kinase) (Dlk) (ZIP-kinase).

MYLK2_HUMAN
θ value	1.56636e-44 (rank : 13)	NC score	0.878967 (rank : 15)
Query Neighborhood Hits	1959	Target Neighborhood Hits	920	Shared Neighborhood Hits	853
SwissProt Accessions	Q9H1R3, Q96I84	Gene names	MYLK2
Domain Architecture
Description	Myosin light chain kinase 2, skeletal/cardiac muscle (EC 2.7.11.18) (MLCK2).

HMCN1_HUMAN
θ value	1.32601e-43 (rank : 14)	NC score	0.290390 (rank : 951)
Query Neighborhood Hits	1959	Target Neighborhood Hits	983	Shared Neighborhood Hits	342
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

TRIO_HUMAN
θ value	3.85808e-43 (rank : 15)	NC score	0.859922 (rank : 89)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1580	Shared Neighborhood Hits	1080
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

DUET_HUMAN
θ value	2.50074e-42 (rank : 16)	NC score	0.897042 (rank : 6)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1220	Shared Neighborhood Hits	1013
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

ST17B_HUMAN
θ value	1.79215e-40 (rank : 17)	NC score	0.879715 (rank : 14)
Query Neighborhood Hits	1959	Target Neighborhood Hits	833	Shared Neighborhood Hits	814
SwissProt Accessions	O94768	Gene names	STK17B, DRAK2
Domain Architecture
Description	Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 2).

ST17B_MOUSE
θ value	8.89434e-40 (rank : 18)	NC score	0.879761 (rank : 13)
Query Neighborhood Hits	1959	Target Neighborhood Hits	838	Shared Neighborhood Hits	818
SwissProt Accessions	Q8BG48, Q3TNG7, Q8BLV9, Q923E7	Gene names	Stk17b, Drak2
Domain Architecture
Description	Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 2).

ST17A_HUMAN
θ value	1.98146e-39 (rank : 19)	NC score	0.881514 (rank : 10)
Query Neighborhood Hits	1959	Target Neighborhood Hits	843	Shared Neighborhood Hits	813
SwissProt Accessions	Q9UEE5, Q8IVC8	Gene names	STK17A, DRAK1
Domain Architecture
Description	Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 1).

OBSL1_HUMAN
θ value	3.37985e-39 (rank : 20)	NC score	0.423459 (rank : 831)
Query Neighborhood Hits	1959	Target Neighborhood Hits	354	Shared Neighborhood Hits	270
SwissProt Accessions	O75147, Q96IW3	Gene names	OBSL1, KIAA0657
Domain Architecture	No domain graphic available
Description	Obscurin-like protein 1 precursor.

PGBM_HUMAN
θ value	2.67802e-36 (rank : 21)	NC score	0.289355 (rank : 955)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1113	Shared Neighborhood Hits	376
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

KCC1D_HUMAN
θ value	4.27553e-34 (rank : 22)	NC score	0.873318 (rank : 22)
Query Neighborhood Hits	1959	Target Neighborhood Hits	846	Shared Neighborhood Hits	820
SwissProt Accessions	Q8IU85, Q9HD31	Gene names	CAMK1D
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK).

KCC1D_MOUSE
θ value	4.27553e-34 (rank : 23)	NC score	0.873447 (rank : 18)
Query Neighborhood Hits	1959	Target Neighborhood Hits	847	Shared Neighborhood Hits	821
SwissProt Accessions	Q8BW96, Q3U450, Q80W64, Q8BWI7	Gene names	Camk1d
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK) (mCKLiK).

KPSH1_HUMAN
θ value	5.584e-34 (rank : 24)	NC score	0.874065 (rank : 16)
Query Neighborhood Hits	1959	Target Neighborhood Hits	842	Shared Neighborhood Hits	818
SwissProt Accessions	P11801, Q9NY19	Gene names	PSKH1
Domain Architecture
Description	Serine/threonine-protein kinase H1 (EC 2.7.11.1) (PSK-H1).

KPSH1_MOUSE
θ value	1.24399e-33 (rank : 25)	NC score	0.874016 (rank : 17)
Query Neighborhood Hits	1959	Target Neighborhood Hits	839	Shared Neighborhood Hits	815
SwissProt Accessions	Q91YA2, Q3U3V3	Gene names	Pskh1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase H1 (EC 2.7.11.1) (PSK-H1).

KCC2D_HUMAN
θ value	2.77131e-33 (rank : 26)	NC score	0.871340 (rank : 32)
Query Neighborhood Hits	1959	Target Neighborhood Hits	830	Shared Neighborhood Hits	808
SwissProt Accessions	Q13557, Q9UGH6, Q9UQE9	Gene names	CAMK2D
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type II delta chain (EC 2.7.11.17) (CaM-kinase II delta chain) (CaM kinase II subunit delta) (CaMK-II subunit delta).

KCC2A_HUMAN
θ value	6.17384e-33 (rank : 27)	NC score	0.870679 (rank : 35)
Query Neighborhood Hits	1959	Target Neighborhood Hits	830	Shared Neighborhood Hits	808
SwissProt Accessions	Q9UQM7, Q9Y352	Gene names	CAMK2A
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type II alpha chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II subunit alpha).

KCC2G_HUMAN
θ value	8.06329e-33 (rank : 28)	NC score	0.872524 (rank : 29)
Query Neighborhood Hits	1959	Target Neighborhood Hits	841	Shared Neighborhood Hits	813
SwissProt Accessions	Q13555, O15378, Q13556, Q5SQZ4	Gene names	CAMK2G
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase type II gamma chain (EC 2.7.11.17) (CaM-kinase II gamma chain) (CaM kinase II gamma subunit) (CaMK-II subunit gamma).

KCC2G_MOUSE
θ value	8.06329e-33 (rank : 29)	NC score	0.872509 (rank : 30)
Query Neighborhood Hits	1959	Target Neighborhood Hits	838	Shared Neighborhood Hits	812
SwissProt Accessions	Q923T9, Q3U3H3, Q8VED3	Gene names	Camk2g
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type II gamma chain (EC 2.7.11.17) (CaM-kinase II gamma chain) (CaM kinase II gamma subunit) (CaMK-II subunit gamma).

KCC2A_MOUSE
θ value	1.0531e-32 (rank : 30)	NC score	0.870614 (rank : 36)
Query Neighborhood Hits	1959	Target Neighborhood Hits	829	Shared Neighborhood Hits	806
SwissProt Accessions	P11798, Q61284	Gene names	Camk2a
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type II alpha chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II subunit alpha).

CSKP_HUMAN
θ value	1.37539e-32 (rank : 31)	NC score	0.822967 (rank : 335)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1022	Shared Neighborhood Hits	816
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

KCC2B_HUMAN
θ value	1.37539e-32 (rank : 32)	NC score	0.871003 (rank : 34)
Query Neighborhood Hits	1959	Target Neighborhood Hits	866	Shared Neighborhood Hits	821
SwissProt Accessions	Q13554, O95437, O95438, O95599, Q9UGH7, Q9UGH8, Q9UGH9, Q9UNX0, Q9UNX7, Q9UP00, Q9Y5N4, Q9Y6F4	Gene names	CAMK2B, CAM2, CAMKB
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type II beta chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II subunit beta) (CaMK-II subunit beta).

KCC2B_MOUSE
θ value	1.37539e-32 (rank : 33)	NC score	0.869066 (rank : 37)
Query Neighborhood Hits	1959	Target Neighborhood Hits	841	Shared Neighborhood Hits	808
SwissProt Accessions	P28652, Q5SVH9	Gene names	Camk2b, Camk2d
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type II beta chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II subunit beta) (CaMK-II subunit beta).

KCC1B_MOUSE
θ value	5.22648e-32 (rank : 34)	NC score	0.873360 (rank : 21)
Query Neighborhood Hits	1959	Target Neighborhood Hits	842	Shared Neighborhood Hits	820
SwissProt Accessions	Q9QYK9, Q80W07	Gene names	Pnck
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase type 1B (EC 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase homolog).

CSKP_MOUSE
θ value	6.82597e-32 (rank : 35)	NC score	0.825228 (rank : 321)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1027	Shared Neighborhood Hits	817
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

KCC1B_HUMAN
θ value	1.98606e-31 (rank : 36)	NC score	0.873215 (rank : 23)
Query Neighborhood Hits	1959	Target Neighborhood Hits	842	Shared Neighborhood Hits	820
SwissProt Accessions	Q6P2M8	Gene names	PNCK
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase type 1B (EC 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase).

KCC1A_HUMAN
θ value	1.6813e-30 (rank : 37)	NC score	0.872726 (rank : 27)
Query Neighborhood Hits	1959	Target Neighborhood Hits	846	Shared Neighborhood Hits	820
SwissProt Accessions	Q14012	Gene names	CAMK1
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha).

KCC1A_MOUSE
θ value	2.19584e-30 (rank : 38)	NC score	0.872801 (rank : 25)
Query Neighborhood Hits	1959	Target Neighborhood Hits	845	Shared Neighborhood Hits	820
SwissProt Accessions	Q91YS8	Gene names	Camk1
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha).

DCAK3_MOUSE
θ value	6.38894e-30 (rank : 39)	NC score	0.872755 (rank : 26)
Query Neighborhood Hits	1959	Target Neighborhood Hits	922	Shared Neighborhood Hits	851
SwissProt Accessions	Q8BWQ5, Q1A748	Gene names	Dcamkl3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL3 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 3) (CLICK-I and II-related) (CLr).

KS6A2_MOUSE
θ value	6.38894e-30 (rank : 40)	NC score	0.854324 (rank : 129)
Query Neighborhood Hits	1959	Target Neighborhood Hits	858	Shared Neighborhood Hits	829
SwissProt Accessions	Q9WUT3, Q9D2C0	Gene names	Rps6ka2, Rsk3
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1) (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (Protein-tyrosine kinase Mpk-9) (MAP kinase- activated protein kinase 1c) (MAPKAPK1C).

DCAK3_HUMAN
θ value	8.3442e-30 (rank : 41)	NC score	0.873361 (rank : 20)
Query Neighborhood Hits	1959	Target Neighborhood Hits	888	Shared Neighborhood Hits	835
SwissProt Accessions	Q9C098	Gene names	DCAMKL3, KIAA1765
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL3 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 3).

KCC4_MOUSE
θ value	1.08979e-29 (rank : 42)	NC score	0.872673 (rank : 28)
Query Neighborhood Hits	1959	Target Neighborhood Hits	899	Shared Neighborhood Hits	827
SwissProt Accessions	P08414, Q61381	Gene names	Camk4
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type IV (EC 2.7.11.17) (CAM kinase-GR) (CaMK IV).

KPSH2_HUMAN
θ value	1.08979e-29 (rank : 43)	NC score	0.873442 (rank : 19)
Query Neighborhood Hits	1959	Target Neighborhood Hits	822	Shared Neighborhood Hits	805
SwissProt Accessions	Q96QS6	Gene names	PSKH2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase H2 (EC 2.7.11.1) (PSK-H2).

KS6A2_HUMAN
θ value	1.08979e-29 (rank : 44)	NC score	0.853873 (rank : 131)
Query Neighborhood Hits	1959	Target Neighborhood Hits	857	Shared Neighborhood Hits	826
SwissProt Accessions	Q15349, Q15419, Q59GJ3, Q5TI68, Q96J38, Q9UJN5	Gene names	RPS6KA2, RSK3
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1) (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (MAP kinase-activated protein kinase 1c) (MAPKAPK1C).

KCC4_HUMAN
θ value	1.85889e-29 (rank : 45)	NC score	0.873094 (rank : 24)
Query Neighborhood Hits	1959	Target Neighborhood Hits	841	Shared Neighborhood Hits	816
SwissProt Accessions	Q16566	Gene names	CAMK4
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type IV (EC 2.7.11.17) (CAM kinase-GR) (CaMK IV).

ROBO2_MOUSE
θ value	1.85889e-29 (rank : 46)	NC score	0.407304 (rank : 841)
Query Neighborhood Hits	1959	Target Neighborhood Hits	504	Shared Neighborhood Hits	332
SwissProt Accessions	Q7TPD3, Q8BJ59	Gene names	Robo2, Kiaa1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

DCAK2_HUMAN
θ value	3.17079e-29 (rank : 47)	NC score	0.860176 (rank : 88)
Query Neighborhood Hits	1959	Target Neighborhood Hits	862	Shared Neighborhood Hits	820
SwissProt Accessions	Q8N568, Q8N399	Gene names	DCAMKL2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL2 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 2).

ROBO2_HUMAN
θ value	3.17079e-29 (rank : 48)	NC score	0.407886 (rank : 839)
Query Neighborhood Hits	1959	Target Neighborhood Hits	479	Shared Neighborhood Hits	323
SwissProt Accessions	Q9HCK4, O43608	Gene names	ROBO2, KIAA1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

KCC1G_MOUSE
θ value	5.40856e-29 (rank : 49)	NC score	0.871402 (rank : 31)
Query Neighborhood Hits	1959	Target Neighborhood Hits	851	Shared Neighborhood Hits	828
SwissProt Accessions	Q91VB2	Gene names	Camk1g
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase type 1G (EC 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM- KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III).

KCC1G_HUMAN
θ value	9.2256e-29 (rank : 50)	NC score	0.871182 (rank : 33)
Query Neighborhood Hits	1959	Target Neighborhood Hits	850	Shared Neighborhood Hits	821
SwissProt Accessions	Q96NX5, Q86UH5, Q9Y3J7	Gene names	CAMK1G, VWS1
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase type 1G (EC 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM- KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III).

MELK_MOUSE
θ value	1.2049e-28 (rank : 51)	NC score	0.864235 (rank : 57)
Query Neighborhood Hits	1959	Target Neighborhood Hits	860	Shared Neighborhood Hits	822
SwissProt Accessions	Q61846, Q61804, Q6ZQH6	Gene names	Melk, Kiaa0175, Pk38
Domain Architecture	No domain graphic available
Description	Maternal embryonic leucine zipper kinase (EC 2.7.11.1) (Protein kinase PK38) (mPK38).

KS6A6_HUMAN
θ value	1.57365e-28 (rank : 52)	NC score	0.853728 (rank : 133)
Query Neighborhood Hits	1959	Target Neighborhood Hits	853	Shared Neighborhood Hits	825
SwissProt Accessions	Q9UK32, Q8WX28, Q9H4S6	Gene names	RPS6KA6, RSK4
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-6 (EC 2.7.11.1) (S6K-alpha 6) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4).

DCAK1_MOUSE
θ value	3.50572e-28 (rank : 53)	NC score	0.860689 (rank : 83)
Query Neighborhood Hits	1959	Target Neighborhood Hits	867	Shared Neighborhood Hits	821
SwissProt Accessions	Q9JLM8, Q6P207	Gene names	Dcamkl1, Dclk
Domain Architecture
Description	Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 1).

DCAK2_MOUSE
θ value	3.50572e-28 (rank : 54)	NC score	0.860636 (rank : 84)
Query Neighborhood Hits	1959	Target Neighborhood Hits	858	Shared Neighborhood Hits	819
SwissProt Accessions	Q6PGN3, Q8BUU0, Q8BX25	Gene names	Dcamkl2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL2 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 2).

KS6A1_MOUSE
θ value	3.50572e-28 (rank : 55)	NC score	0.853741 (rank : 132)
Query Neighborhood Hits	1959	Target Neighborhood Hits	850	Shared Neighborhood Hits	826
SwissProt Accessions	P18653	Gene names	Rps6ka1, Rsk1
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1) (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (p90S6K) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A).

MELK_HUMAN
θ value	3.50572e-28 (rank : 56)	NC score	0.863742 (rank : 58)
Query Neighborhood Hits	1959	Target Neighborhood Hits	847	Shared Neighborhood Hits	819
SwissProt Accessions	Q14680, Q7L3C3	Gene names	MELK, KIAA0175
Domain Architecture	No domain graphic available
Description	Maternal embryonic leucine zipper kinase (EC 2.7.11.1) (hMELK) (Protein kinase PK38) (hPK38).

KS6A3_HUMAN
θ value	4.57862e-28 (rank : 57)	NC score	0.852550 (rank : 143)
Query Neighborhood Hits	1959	Target Neighborhood Hits	859	Shared Neighborhood Hits	827
SwissProt Accessions	P51812, Q4VAP3, Q59H26, Q5JPK8, Q7Z3Z7	Gene names	RPS6KA3, ISPK1, RSK2
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1) (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B).

KS6A3_MOUSE
θ value	4.57862e-28 (rank : 58)	NC score	0.852563 (rank : 142)
Query Neighborhood Hits	1959	Target Neighborhood Hits	860	Shared Neighborhood Hits	827
SwissProt Accessions	P18654, Q03140, Q8K3J8	Gene names	Rps6ka3, Rps6ka-rs1, Rsk2
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1) (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B).

DCAK1_HUMAN
θ value	1.02001e-27 (rank : 59)	NC score	0.860574 (rank : 85)
Query Neighborhood Hits	1959	Target Neighborhood Hits	877	Shared Neighborhood Hits	828
SwissProt Accessions	O15075	Gene names	DCAMKL1, KIAA0369
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 1).

KS6A1_HUMAN
θ value	1.02001e-27 (rank : 60)	NC score	0.853103 (rank : 136)
Query Neighborhood Hits	1959	Target Neighborhood Hits	854	Shared Neighborhood Hits	827
SwissProt Accessions	Q15418, Q5SVM5, Q5SVM8, Q5SVM9, Q96C05, Q9BQK2	Gene names	RPS6KA1, RSK1
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1) (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (p90S6K) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A).

SN1L1_MOUSE
θ value	1.33217e-27 (rank : 61)	NC score	0.859689 (rank : 91)
Query Neighborhood Hits	1959	Target Neighborhood Hits	895	Shared Neighborhood Hits	843
SwissProt Accessions	Q60670	Gene names	Snf1lk, Msk
Domain Architecture
Description	Serine/threonine-protein kinase SNF1-like kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) (HRT-20) (Myocardial SNF1- like kinase).

PHKG1_HUMAN
θ value	2.27234e-27 (rank : 62)	NC score	0.865148 (rank : 51)
Query Neighborhood Hits	1959	Target Neighborhood Hits	838	Shared Neighborhood Hits	818
SwissProt Accessions	Q16816	Gene names	PHKG1, PHKG
Domain Architecture
Description	Phosphorylase b kinase gamma catalytic chain, skeletal muscle isoform (EC 2.7.11.19) (Phosphorylase kinase subunit gamma 1).

AURKB_MOUSE
θ value	8.63488e-27 (rank : 63)	NC score	0.865880 (rank : 48)
Query Neighborhood Hits	1959	Target Neighborhood Hits	858	Shared Neighborhood Hits	830
SwissProt Accessions	O70126, Q61882	Gene names	Aurkb, Ark2, Stk1, Stk12, Stk5
Domain Architecture
Description	Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-B) (Aurora- related kinase 2) (Serine/threonine-protein kinase 5) (STK-1).

NUAK2_HUMAN
θ value	1.47289e-26 (rank : 64)	NC score	0.863695 (rank : 59)
Query Neighborhood Hits	1959	Target Neighborhood Hits	874	Shared Neighborhood Hits	830
SwissProt Accessions	Q9H093	Gene names	NUAK2
Domain Architecture	No domain graphic available
Description	NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (SNF1/AMP kinase-related kinase) (SNARK).

ROBO1_HUMAN
θ value	1.47289e-26 (rank : 65)	NC score	0.408671 (rank : 836)
Query Neighborhood Hits	1959	Target Neighborhood Hits	529	Shared Neighborhood Hits	342
SwissProt Accessions	Q9Y6N7, Q7Z300, Q9BUS7	Gene names	ROBO1, DUTT1
Domain Architecture
Description	Roundabout homolog 1 precursor (H-Robo-1) (Deleted in U twenty twenty).

STK6_HUMAN
θ value	1.92365e-26 (rank : 66)	NC score	0.865951 (rank : 47)
Query Neighborhood Hits	1959	Target Neighborhood Hits	916	Shared Neighborhood Hits	847
SwissProt Accessions	O14965, O60445, O75873, Q9BQD6, Q9UPG5	Gene names	STK6, AIK, ARK1, AURA, BTAK, STK15
Domain Architecture
Description	Serine/threonine-protein kinase 6 (EC 2.7.11.1) (Serine/threonine kinase 15) (Aurora/IPL1-related kinase 1) (Aurora-related kinase 1) (hARK1) (Aurora-A) (Breast-tumor-amplified kinase).

BRSK1_HUMAN
θ value	3.28125e-26 (rank : 67)	NC score	0.864987 (rank : 53)
Query Neighborhood Hits	1959	Target Neighborhood Hits	942	Shared Neighborhood Hits	862
SwissProt Accessions	Q8TDC3, Q5J5B5, Q8NDD0, Q8NDR4, Q8TDC2, Q96AV4, Q96JL4	Gene names	BRSK1, KIAA1811, SAD1
Domain Architecture
Description	BR serine/threonine-protein kinase 1 (EC 2.7.11.1) (SAD1 kinase) (SAD1A).

PHKG2_HUMAN
θ value	3.28125e-26 (rank : 68)	NC score	0.867829 (rank : 41)
Query Neighborhood Hits	1959	Target Neighborhood Hits	839	Shared Neighborhood Hits	819
SwissProt Accessions	P15735, P11800	Gene names	PHKG2
Domain Architecture
Description	Phosphorylase b kinase gamma catalytic chain, testis/liver isoform (EC 2.7.11.19) (PHK-gamma-T) (Phosphorylase kinase subunit gamma 2) (PSK-C3).

PLK3_MOUSE
θ value	3.28125e-26 (rank : 69)	NC score	0.863583 (rank : 62)
Query Neighborhood Hits	1959	Target Neighborhood Hits	863	Shared Neighborhood Hits	826
SwissProt Accessions	Q60806, Q60822, Q9R009	Gene names	Plk3, Cnk, Fnk
Domain Architecture
Description	Serine/threonine-protein kinase PLK3 (EC 2.7.11.21) (Polo-like kinase 3) (PLK-3) (Cytokine-inducible serine/threonine-protein kinase) (FGF- inducible kinase).

CNTN4_HUMAN
θ value	4.28545e-26 (rank : 70)	NC score	0.389963 (rank : 868)
Query Neighborhood Hits	1959	Target Neighborhood Hits	449	Shared Neighborhood Hits	318
SwissProt Accessions	Q8IWV2, Q8IX14, Q8TC35	Gene names	CNTN4
Domain Architecture	No domain graphic available
Description	Contactin-4 precursor (Brain-derived immunoglobulin superfamily protein 2) (BIG-2).

ROBO1_MOUSE
θ value	4.28545e-26 (rank : 71)	NC score	0.408675 (rank : 835)
Query Neighborhood Hits	1959	Target Neighborhood Hits	559	Shared Neighborhood Hits	362
SwissProt Accessions	O89026	Gene names	Robo1, Dutt1
Domain Architecture
Description	Roundabout homolog 1 precursor.

DCC_HUMAN
θ value	7.30988e-26 (rank : 72)	NC score	0.396758 (rank : 853)
Query Neighborhood Hits	1959	Target Neighborhood Hits	583	Shared Neighborhood Hits	398
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

DCC_MOUSE
θ value	7.30988e-26 (rank : 73)	NC score	0.400187 (rank : 849)
Query Neighborhood Hits	1959	Target Neighborhood Hits	896	Shared Neighborhood Hits	545
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

STK33_HUMAN
θ value	7.30988e-26 (rank : 74)	NC score	0.869002 (rank : 38)
Query Neighborhood Hits	1959	Target Neighborhood Hits	879	Shared Neighborhood Hits	827
SwissProt Accessions	Q9BYT3, Q658S6, Q8NEF5	Gene names	STK33
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 33 (EC 2.7.11.1).

CNTN4_MOUSE
θ value	9.54697e-26 (rank : 75)	NC score	0.390386 (rank : 865)
Query Neighborhood Hits	1959	Target Neighborhood Hits	445	Shared Neighborhood Hits	316
SwissProt Accessions	Q69Z26, Q8BRT6, Q8CBD3	Gene names	Cntn4, Kiaa3024
Domain Architecture	No domain graphic available
Description	Contactin-4 precursor (Brain-derived immunoglobulin superfamily protein 2) (BIG-2).

PGBM_MOUSE
θ value	9.54697e-26 (rank : 76)	NC score	0.279851 (rank : 968)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1073	Shared Neighborhood Hits	354
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

SN1L1_HUMAN
θ value	9.54697e-26 (rank : 77)	NC score	0.859079 (rank : 94)
Query Neighborhood Hits	1959	Target Neighborhood Hits	911	Shared Neighborhood Hits	842
SwissProt Accessions	P57059, Q5R2V5, Q86YJ2	Gene names	SNF1LK
Domain Architecture
Description	Serine/threonine-protein kinase SNF1-like kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase SNF1LK).

NUAK2_MOUSE
θ value	1.24688e-25 (rank : 78)	NC score	0.863193 (rank : 66)
Query Neighborhood Hits	1959	Target Neighborhood Hits	878	Shared Neighborhood Hits	832
SwissProt Accessions	Q8BZN4, Q80ZW3, Q8CIC0, Q9DBV0	Gene names	Nuak2
Domain Architecture	No domain graphic available
Description	NUAK family SNF1-like kinase 2 (EC 2.7.11.1).

STK6_MOUSE
θ value	1.24688e-25 (rank : 79)	NC score	0.866011 (rank : 46)
Query Neighborhood Hits	1959	Target Neighborhood Hits	886	Shared Neighborhood Hits	845
SwissProt Accessions	P97477, O35624, Q91YU4	Gene names	Stk6, Ark1, Aurka, Ayk1, Iak1
Domain Architecture
Description	Serine/threonine-protein kinase 6 (EC 2.7.11.1) (Aurora-family kinase 1) (Aurora/IPL1-related kinase 1) (Ipl1- and aurora-related kinase 1) (Aurora-A) (Serine/threonine-protein kinase Ayk1).

PAK7_HUMAN
θ value	1.62847e-25 (rank : 80)	NC score	0.851076 (rank : 153)
Query Neighborhood Hits	1959	Target Neighborhood Hits	875	Shared Neighborhood Hits	835
SwissProt Accessions	Q9P286, Q5W115, Q9BX09, Q9ULF6	Gene names	PAK7, KIAA1264, PAK5
Domain Architecture
Description	Serine/threonine-protein kinase PAK 7 (EC 2.7.11.1) (p21-activated kinase 7) (PAK-7) (PAK-5).

PAK7_MOUSE
θ value	1.62847e-25 (rank : 81)	NC score	0.851229 (rank : 152)
Query Neighborhood Hits	1959	Target Neighborhood Hits	875	Shared Neighborhood Hits	836
SwissProt Accessions	Q8C015, Q3TQJ7, Q6RWS7	Gene names	Pak7, Pak5
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PAK 7 (EC 2.7.11.1) (p21-activated kinase 7) (PAK-7) (p21-activated kinase 5).

PHKG2_MOUSE
θ value	1.62847e-25 (rank : 82)	NC score	0.867914 (rank : 40)
Query Neighborhood Hits	1959	Target Neighborhood Hits	841	Shared Neighborhood Hits	822
SwissProt Accessions	Q9DB30	Gene names	Phkg2
Domain Architecture
Description	Phosphorylase b kinase gamma catalytic chain, testis/liver isoform (EC 2.7.11.19) (PHK-gamma-T) (Phosphorylase kinase subunit gamma 2).

CHK2_MOUSE
θ value	2.77775e-25 (rank : 83)	NC score	0.868757 (rank : 39)
Query Neighborhood Hits	1959	Target Neighborhood Hits	860	Shared Neighborhood Hits	817
SwissProt Accessions	Q9Z265	Gene names	Chek2, Chk2, Rad53
Domain Architecture
Description	Serine/threonine-protein kinase Chk2 (EC 2.7.11.1).

PAK6_HUMAN
θ value	8.08199e-25 (rank : 84)	NC score	0.852829 (rank : 141)
Query Neighborhood Hits	1959	Target Neighborhood Hits	915	Shared Neighborhood Hits	869
SwissProt Accessions	Q9NQU5	Gene names	PAK6, PAK5
Domain Architecture
Description	Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1) (p21-activated kinase 6) (PAK-6) (PAK-5).

PLK4_MOUSE
θ value	8.08199e-25 (rank : 85)	NC score	0.866061 (rank : 45)
Query Neighborhood Hits	1959	Target Neighborhood Hits	879	Shared Neighborhood Hits	832
SwissProt Accessions	Q64702, Q6PEP6, Q78EG6, Q8R0I5, Q9CVR6, Q9CVU6	Gene names	Plk4, Sak, Stk18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine- protein kinase 18).

STK36_HUMAN
θ value	1.05554e-24 (rank : 86)	NC score	0.859870 (rank : 90)
Query Neighborhood Hits	1959	Target Neighborhood Hits	896	Shared Neighborhood Hits	833
SwissProt Accessions	Q9NRP7, Q8TC32, Q9H9N9, Q9UF35, Q9ULE2	Gene names	STK36, KIAA1278
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog).

PLK3_HUMAN
θ value	1.37858e-24 (rank : 87)	NC score	0.863187 (rank : 67)
Query Neighborhood Hits	1959	Target Neighborhood Hits	865	Shared Neighborhood Hits	827
SwissProt Accessions	Q9H4B4, Q15767, Q96CV1	Gene names	PLK3, CNK, FNK, PRK
Domain Architecture
Description	Serine/threonine-protein kinase PLK3 (EC 2.7.11.21) (Polo-like kinase 3) (PLK-3) (Cytokine-inducible serine/threonine-protein kinase) (FGF- inducible kinase) (Proliferation-related kinase).

ROBO3_HUMAN
θ value	1.37858e-24 (rank : 88)	NC score	0.408318 (rank : 837)
Query Neighborhood Hits	1959	Target Neighborhood Hits	570	Shared Neighborhood Hits	388
SwissProt Accessions	Q96MS0	Gene names	ROBO3
Domain Architecture
Description	Roundabout homolog 3 precursor (Roundabout-like protein 3).

AKT3_HUMAN
θ value	1.80048e-24 (rank : 89)	NC score	0.846258 (rank : 183)
Query Neighborhood Hits	1959	Target Neighborhood Hits	872	Shared Neighborhood Hits	822
SwissProt Accessions	Q9Y243, Q96QV3, Q9UFP5	Gene names	AKT3
Domain Architecture
Description	RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) (STK-2).

AKT3_MOUSE
θ value	1.80048e-24 (rank : 90)	NC score	0.846238 (rank : 185)
Query Neighborhood Hits	1959	Target Neighborhood Hits	872	Shared Neighborhood Hits	822
SwissProt Accessions	Q9WUA6	Gene names	Akt3
Domain Architecture
Description	RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma).

PAK3_MOUSE
θ value	1.80048e-24 (rank : 91)	NC score	0.848241 (rank : 165)
Query Neighborhood Hits	1959	Target Neighborhood Hits	874	Shared Neighborhood Hits	829
SwissProt Accessions	Q61036, O88645, Q8K1R5, Q8K1R6	Gene names	Pak3, Pak-3, Pakb, Stk4
Domain Architecture
Description	Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (p21-activated kinase 3) (PAK-3) (Beta-PAK) (CDC42/RAC effector kinase PAK-B).

PHKG1_MOUSE
θ value	2.35151e-24 (rank : 92)	NC score	0.864920 (rank : 54)
Query Neighborhood Hits	1959	Target Neighborhood Hits	840	Shared Neighborhood Hits	818
SwissProt Accessions	P07934	Gene names	Phkg1, Phkg
Domain Architecture
Description	Phosphorylase b kinase gamma catalytic chain, skeletal muscle isoform (EC 2.7.11.19) (Phosphorylase kinase subunit gamma 1).

PAK3_HUMAN
θ value	3.07116e-24 (rank : 93)	NC score	0.848303 (rank : 164)
Query Neighborhood Hits	1959	Target Neighborhood Hits	887	Shared Neighborhood Hits	836
SwissProt Accessions	O75914, Q5JWX1, Q5JWX2, Q7Z2D6, Q7Z2E4, Q7Z3Z8, Q8WWK5, Q8WX23, Q9P0J8	Gene names	PAK3, OPHN3
Domain Architecture
Description	Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (p21-activated kinase 3) (PAK-3) (Beta-PAK) (Oligophrenin-3).

PLK4_HUMAN
θ value	3.07116e-24 (rank : 94)	NC score	0.866311 (rank : 44)
Query Neighborhood Hits	1959	Target Neighborhood Hits	884	Shared Neighborhood Hits	834
SwissProt Accessions	O00444, Q8IYF0, Q96Q95	Gene names	PLK4, SAK, STK18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine- protein kinase 18).

SN1L2_MOUSE
θ value	3.07116e-24 (rank : 95)	NC score	0.856900 (rank : 115)
Query Neighborhood Hits	1959	Target Neighborhood Hits	944	Shared Neighborhood Hits	869
SwissProt Accessions	Q8CFH6	Gene names	Snf1lk2, Sik2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SNF1-like kinase 2 (EC 2.7.11.1) (Salt-inducible kinase 2).

MYPN_HUMAN
θ value	6.84181e-24 (rank : 96)	NC score	0.407559 (rank : 840)
Query Neighborhood Hits	1959	Target Neighborhood Hits	418	Shared Neighborhood Hits	324
SwissProt Accessions	Q86TC9, Q5VV35, Q5VV36, Q86T37, Q8N3L4, Q96K90, Q96KF5	Gene names	MYPN, MYOP
Domain Architecture	No domain graphic available
Description	Myopalladin (145 kDa sarcomeric protein).

PLK2_HUMAN
θ value	6.84181e-24 (rank : 97)	NC score	0.861632 (rank : 75)
Query Neighborhood Hits	1959	Target Neighborhood Hits	854	Shared Neighborhood Hits	827
SwissProt Accessions	Q9NYY3, O60679, Q96CV7, Q9UE61	Gene names	PLK2, SNK
Domain Architecture
Description	Serine/threonine-protein kinase PLK2 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-2) (Serine/threonine-protein kinase SNK) (Serum-inducible kinase).

PLK2_MOUSE
θ value	6.84181e-24 (rank : 98)	NC score	0.861313 (rank : 78)
Query Neighborhood Hits	1959	Target Neighborhood Hits	849	Shared Neighborhood Hits	825
SwissProt Accessions	P53351	Gene names	Plk2, Snk
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PLK2 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-2) (Serine/threonine-protein kinase SNK) (Serum-inducible kinase).

SNRK_MOUSE
θ value	6.84181e-24 (rank : 99)	NC score	0.863660 (rank : 60)
Query Neighborhood Hits	1959	Target Neighborhood Hits	849	Shared Neighborhood Hits	810
SwissProt Accessions	Q8VDU5, Q91WX6	Gene names	Snrk
Domain Architecture	No domain graphic available
Description	SNF-related serine/threonine-protein kinase (EC 2.7.11.1) (SNF1- related kinase).

CNTN6_MOUSE
θ value	8.93572e-24 (rank : 100)	NC score	0.386297 (rank : 879)
Query Neighborhood Hits	1959	Target Neighborhood Hits	429	Shared Neighborhood Hits	313
SwissProt Accessions	Q9JMB8, Q8C6X1	Gene names	Cntn6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (mNB-3).

KPCD1_HUMAN
θ value	8.93572e-24 (rank : 101)	NC score	0.858869 (rank : 97)
Query Neighborhood Hits	1959	Target Neighborhood Hits	901	Shared Neighborhood Hits	820
SwissProt Accessions	Q15139	Gene names	PRKD1, PKD, PKD1, PRKCM
Domain Architecture
Description	Serine/threonine-protein kinase D1 (EC 2.7.11.13) (nPKC-D1) (Protein kinase D) (Protein kinase C mu type) (nPKC-mu).

MARK1_HUMAN
θ value	8.93572e-24 (rank : 102)	NC score	0.855044 (rank : 124)
Query Neighborhood Hits	1959	Target Neighborhood Hits	887	Shared Neighborhood Hits	836
SwissProt Accessions	Q9P0L2, Q5VTF9, Q5VTG0, Q96SW9, Q9P251	Gene names	MARK1, KIAA1477, MARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MARK1 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 1).

MYPN_MOUSE
θ value	8.93572e-24 (rank : 103)	NC score	0.405163 (rank : 843)
Query Neighborhood Hits	1959	Target Neighborhood Hits	421	Shared Neighborhood Hits	315
SwissProt Accessions	Q5DTJ9, Q7TPW5, Q8BZ76	Gene names	Mypn, Kiaa4170
Domain Architecture	No domain graphic available
Description	Myopalladin.

AURKC_MOUSE
θ value	1.16704e-23 (rank : 104)	NC score	0.866930 (rank : 43)
Query Neighborhood Hits	1959	Target Neighborhood Hits	844	Shared Neighborhood Hits	828
SwissProt Accessions	O88445, Q9JLC2	Gene names	Aurkc, Aie1, Stk13
Domain Architecture
Description	Serine/threonine-protein kinase 13 (EC 2.7.11.1) (Aurora/Ipl1/Eg2 protein 1) (Aurora-C).

SN1L2_HUMAN
θ value	1.16704e-23 (rank : 105)	NC score	0.857284 (rank : 110)
Query Neighborhood Hits	1959	Target Neighborhood Hits	964	Shared Neighborhood Hits	881
SwissProt Accessions	Q9H0K1, O94878, Q6AZE2, Q76N03, Q8NCV7, Q96CZ8	Gene names	SNF1LK2, KIAA0781, QIK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SNF1-like kinase 2 (EC 2.7.11.1) (Qin- induced kinase).

CHK2_HUMAN
θ value	1.5242e-23 (rank : 106)	NC score	0.867714 (rank : 42)
Query Neighborhood Hits	1959	Target Neighborhood Hits	859	Shared Neighborhood Hits	817
SwissProt Accessions	O96017, Q6QA03, Q6QA04, Q6QA05, Q6QA06, Q6QA07, Q6QA08, Q6QA10, Q6QA11, Q6QA12, Q6QA13, Q9HCQ8, Q9UGF0, Q9UGF1	Gene names	CHEK2, CHK2
Domain Architecture
Description	Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (Cds1).

KPCD1_MOUSE
θ value	1.99067e-23 (rank : 107)	NC score	0.858581 (rank : 98)
Query Neighborhood Hits	1959	Target Neighborhood Hits	891	Shared Neighborhood Hits	821
SwissProt Accessions	Q62101	Gene names	Prkd1, Pkcm, Pkd, Prkcm
Domain Architecture
Description	Serine/threonine-protein kinase D1 (EC 2.7.11.13) (nPKC-D1) (Protein kinase D) (Protein kinase C mu type) (nPKC-mu).

AKT2_MOUSE
θ value	2.59989e-23 (rank : 108)	NC score	0.844763 (rank : 194)
Query Neighborhood Hits	1959	Target Neighborhood Hits	875	Shared Neighborhood Hits	819
SwissProt Accessions	Q60823	Gene names	Akt2
Domain Architecture
Description	RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta).

KPCD3_MOUSE
θ value	2.59989e-23 (rank : 109)	NC score	0.857241 (rank : 112)
Query Neighborhood Hits	1959	Target Neighborhood Hits	901	Shared Neighborhood Hits	818
SwissProt Accessions	Q8K1Y2	Gene names	Prkd3, Prkcn
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (nPKC-nu).

BRSK2_HUMAN
θ value	3.39556e-23 (rank : 110)	NC score	0.863405 (rank : 64)
Query Neighborhood Hits	1959	Target Neighborhood Hits	897	Shared Neighborhood Hits	841
SwissProt Accessions	Q8IWQ3, O60843, O95099, Q5J5B4, Q8TB60	Gene names	BRSK2, C11orf7, PEN11B, STK29
Domain Architecture
Description	BR serine/threonine-protein kinase 2 (EC 2.7.11.1) (Serine/threonine- protein kinase 29) (SAD1B).

KS6A5_HUMAN
θ value	3.39556e-23 (rank : 111)	NC score	0.850012 (rank : 159)
Query Neighborhood Hits	1959	Target Neighborhood Hits	855	Shared Neighborhood Hits	826
SwissProt Accessions	O75582, O95316, Q96AF7	Gene names	RPS6KA5, MSK1
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear mitogen- and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RSKL).

NFASC_HUMAN
θ value	3.39556e-23 (rank : 112)	NC score	0.394069 (rank : 859)
Query Neighborhood Hits	1959	Target Neighborhood Hits	497	Shared Neighborhood Hits	354
SwissProt Accessions	O94856, Q5T2F0, Q5T2F1, Q5T2F2, Q5T2F3, Q5T2F4, Q5T2F5, Q5T2F6, Q5T2F7, Q5T2F9, Q5T2G0, Q5W9F8, Q68DH3, Q6ZQV6, Q7Z3K1, Q96HT1, Q96K50	Gene names	NFASC, KIAA0756
Domain Architecture
Description	Neurofascin precursor.

AKT2_HUMAN
θ value	4.43474e-23 (rank : 113)	NC score	0.845329 (rank : 189)
Query Neighborhood Hits	1959	Target Neighborhood Hits	878	Shared Neighborhood Hits	819
SwissProt Accessions	P31751, Q68GC0	Gene names	AKT2
Domain Architecture
Description	RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta).

SNRK_HUMAN
θ value	5.79196e-23 (rank : 114)	NC score	0.864395 (rank : 55)
Query Neighborhood Hits	1959	Target Neighborhood Hits	855	Shared Neighborhood Hits	811
SwissProt Accessions	Q9NRH2, Q14706, Q68D15, Q6IQ46, Q9NXI7	Gene names	SNRK, KIAA0096, SNFRK
Domain Architecture	No domain graphic available
Description	SNF-related serine/threonine-protein kinase (EC 2.7.11.1) (SNF1- related kinase).

KPCD3_HUMAN
θ value	7.56453e-23 (rank : 115)	NC score	0.856749 (rank : 116)
Query Neighborhood Hits	1959	Target Neighborhood Hits	895	Shared Neighborhood Hits	819
SwissProt Accessions	O94806	Gene names	PRKD3, EPK2, PRKCN
Domain Architecture
Description	Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (nPKC-nu) (Protein kinase EPK2).

AURKC_HUMAN
θ value	9.87957e-23 (rank : 116)	NC score	0.865287 (rank : 50)
Query Neighborhood Hits	1959	Target Neighborhood Hits	847	Shared Neighborhood Hits	826
SwissProt Accessions	Q9UQB9, O60681, O75442, Q9UPK5	Gene names	AURKC, AIE2, AIK3, STK13
Domain Architecture
Description	Serine/threonine-protein kinase 13 (EC 2.7.11.1) (Aurora/Ipl1/Eg2 protein 2) (Aurora/Ipl1-related kinase 3) (Aurora-C).

K0999_HUMAN
θ value	9.87957e-23 (rank : 117)	NC score	0.857317 (rank : 109)
Query Neighborhood Hits	1959	Target Neighborhood Hits	899	Shared Neighborhood Hits	831
SwissProt Accessions	Q9Y2K2, Q59FY2, Q5M9N1, Q6P3R6, Q8IYM8, Q9HA50	Gene names	KIAA0999
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase KIAA0999 (EC 2.7.11.1).

K0999_MOUSE
θ value	9.87957e-23 (rank : 118)	NC score	0.857419 (rank : 108)
Query Neighborhood Hits	1959	Target Neighborhood Hits	931	Shared Neighborhood Hits	849
SwissProt Accessions	Q6P4S6, Q641L5, Q66JZ5, Q6ZQ09, Q8K075, Q9CYD5	Gene names	Kiaa0999
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase KIAA0999 (EC 2.7.11.1).

MARK2_MOUSE
θ value	9.87957e-23 (rank : 119)	NC score	0.856919 (rank : 114)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1018	Shared Neighborhood Hits	899
SwissProt Accessions	Q05512, Q6PDR4, Q8BR95	Gene names	Mark2, Emk
Domain Architecture
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1).

PAK2_HUMAN
θ value	9.87957e-23 (rank : 120)	NC score	0.850377 (rank : 157)
Query Neighborhood Hits	1959	Target Neighborhood Hits	862	Shared Neighborhood Hits	833
SwissProt Accessions	Q13177, Q13154	Gene names	PAK2
Domain Architecture
Description	Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (p21-activated kinase 2) (PAK-2) (PAK65) (Gamma-PAK) (S6/H4 kinase).

PAK2_MOUSE
θ value	9.87957e-23 (rank : 121)	NC score	0.850296 (rank : 158)
Query Neighborhood Hits	1959	Target Neighborhood Hits	858	Shared Neighborhood Hits	831
SwissProt Accessions	Q8CIN4	Gene names	Pak2
Domain Architecture
Description	Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (p21-activated kinase 2) (PAK-2).

CNTN6_HUMAN
θ value	1.29031e-22 (rank : 122)	NC score	0.384260 (rank : 882)
Query Neighborhood Hits	1959	Target Neighborhood Hits	422	Shared Neighborhood Hits	309
SwissProt Accessions	Q9UQ52	Gene names	CNTN6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (hNB-3).

MARK2_HUMAN
θ value	1.29031e-22 (rank : 123)	NC score	0.857654 (rank : 106)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1056	Shared Neighborhood Hits	914
SwissProt Accessions	Q7KZI7, Q15449, Q15524, Q5XGA3, Q68A18, Q96HB3, Q96RG0	Gene names	MARK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog).

NFASC_MOUSE
θ value	1.29031e-22 (rank : 124)	NC score	0.395441 (rank : 856)
Query Neighborhood Hits	1959	Target Neighborhood Hits	475	Shared Neighborhood Hits	349
SwissProt Accessions	Q810U3	Gene names	Nfasc
Domain Architecture
Description	Neurofascin precursor.

STK36_MOUSE
θ value	1.29031e-22 (rank : 125)	NC score	0.857278 (rank : 111)
Query Neighborhood Hits	1959	Target Neighborhood Hits	877	Shared Neighborhood Hits	829
SwissProt Accessions	Q69ZM6, Q6PDI0, Q80XQ6	Gene names	Stk36, Kiaa1278
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog).

MARK1_MOUSE
θ value	1.6852e-22 (rank : 126)	NC score	0.854691 (rank : 126)
Query Neighborhood Hits	1959	Target Neighborhood Hits	886	Shared Neighborhood Hits	834
SwissProt Accessions	Q8VHJ5, Q69ZI7	Gene names	Mark1, Emk3, Kiaa1477
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MARK1 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 1) (ELKL motif serine/threonine-protein kinase 3).

NEO1_MOUSE
θ value	1.6852e-22 (rank : 127)	NC score	0.393056 (rank : 862)
Query Neighborhood Hits	1959	Target Neighborhood Hits	523	Shared Neighborhood Hits	349
SwissProt Accessions	P97798	Gene names	Neo1, Ngn
Domain Architecture
Description	Neogenin precursor.

AKT1_HUMAN
θ value	2.20094e-22 (rank : 128)	NC score	0.841513 (rank : 211)
Query Neighborhood Hits	1959	Target Neighborhood Hits	885	Shared Neighborhood Hits	818
SwissProt Accessions	P31749, Q9BWB6	Gene names	AKT1, PKB, RAC
Domain Architecture
Description	RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-alpha) (Protein kinase B) (PKB) (C-AKT).

AKT1_MOUSE
θ value	2.20094e-22 (rank : 129)	NC score	0.841234 (rank : 213)
Query Neighborhood Hits	1959	Target Neighborhood Hits	878	Shared Neighborhood Hits	818
SwissProt Accessions	P31750, Q62274	Gene names	Akt1, Akt, Rac
Domain Architecture
Description	RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-alpha) (AKT1 kinase) (Protein kinase B) (PKB) (C-AKT) (Thymoma viral proto- oncogene).

HUNK_HUMAN
θ value	2.20094e-22 (rank : 130)	NC score	0.862972 (rank : 68)
Query Neighborhood Hits	1959	Target Neighborhood Hits	884	Shared Neighborhood Hits	829
SwissProt Accessions	P57058	Gene names	HUNK, MAKV
Domain Architecture
Description	Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (Serine/threonine-protein kinase MAK-V) (B19).

MARK4_HUMAN
θ value	2.20094e-22 (rank : 131)	NC score	0.857992 (rank : 101)
Query Neighborhood Hits	1959	Target Neighborhood Hits	886	Shared Neighborhood Hits	845
SwissProt Accessions	Q96L34, Q8NG37, Q96JG7, Q96SQ2, Q9BYD8	Gene names	MARK4, KIAA1860, MARKL1
Domain Architecture
Description	MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase-like 1).

MARK4_MOUSE
θ value	2.20094e-22 (rank : 132)	NC score	0.857630 (rank : 107)
Query Neighborhood Hits	1959	Target Neighborhood Hits	898	Shared Neighborhood Hits	838
SwissProt Accessions	Q8CIP4, Q80T81	Gene names	Mark4, Kiaa1860
Domain Architecture	No domain graphic available
Description	MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1).

PAK1_HUMAN
θ value	2.20094e-22 (rank : 133)	NC score	0.848475 (rank : 163)
Query Neighborhood Hits	1959	Target Neighborhood Hits	873	Shared Neighborhood Hits	841
SwissProt Accessions	Q13153, O75561, Q13567, Q32M53, Q32M54, Q86W79	Gene names	PAK1
Domain Architecture
Description	Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (p21-activated kinase 1) (PAK-1) (P65-PAK) (Alpha-PAK).

HUNK_MOUSE
θ value	2.87452e-22 (rank : 134)	NC score	0.863221 (rank : 65)
Query Neighborhood Hits	1959	Target Neighborhood Hits	874	Shared Neighborhood Hits	828
SwissProt Accessions	O88866	Gene names	Hunk, Makv
Domain Architecture
Description	Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (Serine/threonine-protein kinase MAK-V).

MARK3_MOUSE
θ value	2.87452e-22 (rank : 135)	NC score	0.856019 (rank : 119)
Query Neighborhood Hits	1959	Target Neighborhood Hits	919	Shared Neighborhood Hits	846
SwissProt Accessions	Q03141, Q3TM40, Q3V1U3, Q8C6G9, Q8R375, Q9JKE4	Gene names	Mark3, Emk2, Mpk10
Domain Architecture	No domain graphic available
Description	MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (MPK-10) (ELKL motif kinase 2).

NEO1_HUMAN
θ value	3.75424e-22 (rank : 136)	NC score	0.393573 (rank : 861)
Query Neighborhood Hits	1959	Target Neighborhood Hits	530	Shared Neighborhood Hits	346
SwissProt Accessions	Q92859, O00340	Gene names	NEO1, NGN
Domain Architecture
Description	Neogenin precursor.

CAMKV_HUMAN
θ value	6.40375e-22 (rank : 137)	NC score	0.852500 (rank : 144)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1084	Shared Neighborhood Hits	897
SwissProt Accessions	Q8NCB2, Q6FIB8, Q8NBS8, Q8NC85, Q8NDU4, Q8WTT8, Q9BQC9, Q9H0Q5	Gene names	CAMKV
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

CAMKV_MOUSE
θ value	6.40375e-22 (rank : 138)	NC score	0.853570 (rank : 134)
Query Neighborhood Hits	1959	Target Neighborhood Hits	848	Shared Neighborhood Hits	798
SwissProt Accessions	Q3UHL1, Q8VD20	Gene names	Camkv
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

KPCD2_HUMAN
θ value	6.40375e-22 (rank : 139)	NC score	0.859348 (rank : 92)
Query Neighborhood Hits	1959	Target Neighborhood Hits	910	Shared Neighborhood Hits	822
SwissProt Accessions	Q9BZL6, Q8TB08, Q9P0T6, Q9Y3X8	Gene names	PRKD2, PKD2
Domain Architecture
Description	Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2).

ULK3_MOUSE
θ value	6.40375e-22 (rank : 140)	NC score	0.865122 (rank : 52)
Query Neighborhood Hits	1959	Target Neighborhood Hits	872	Shared Neighborhood Hits	824
SwissProt Accessions	Q3U3Q1, Q8K1X6, Q9DBR8	Gene names	Ulk3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3).

CNTN5_HUMAN
θ value	8.36355e-22 (rank : 141)	NC score	0.392445 (rank : 863)
Query Neighborhood Hits	1959	Target Neighborhood Hits	446	Shared Neighborhood Hits	334
SwissProt Accessions	O94779, O94780	Gene names	CNTN5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2) (hNB-2).

PAK1_MOUSE
θ value	8.36355e-22 (rank : 142)	NC score	0.848095 (rank : 166)
Query Neighborhood Hits	1959	Target Neighborhood Hits	878	Shared Neighborhood Hits	844
SwissProt Accessions	O88643	Gene names	Pak1, Paka
Domain Architecture
Description	Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (p21-activated kinase 1) (PAK-1) (P65-PAK) (Alpha-PAK) (CDC42/RAC effector kinase PAK-A).

NUAK1_HUMAN
θ value	1.09232e-21 (rank : 143)	NC score	0.861932 (rank : 73)
Query Neighborhood Hits	1959	Target Neighborhood Hits	874	Shared Neighborhood Hits	831
SwissProt Accessions	O60285, Q96KA8	Gene names	NUAK1, ARK5, KIAA0537
Domain Architecture	No domain graphic available
Description	NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase 5).

NUAK1_MOUSE
θ value	1.09232e-21 (rank : 144)	NC score	0.862008 (rank : 72)
Query Neighborhood Hits	1959	Target Neighborhood Hits	881	Shared Neighborhood Hits	839
SwissProt Accessions	Q641K5, Q6I6D6, Q8CGE1	Gene names	Nuak1, Kiaa0537
Domain Architecture	No domain graphic available
Description	NUAK family SNF1-like kinase 1 (EC 2.7.11.1).

AAPK2_HUMAN
θ value	1.42661e-21 (rank : 145)	NC score	0.860185 (rank : 87)
Query Neighborhood Hits	1959	Target Neighborhood Hits	843	Shared Neighborhood Hits	824
SwissProt Accessions	P54646, Q9H1E8, Q9UD43	Gene names	PRKAA2, AMPK, AMPK2
Domain Architecture
Description	5'-AMP-activated protein kinase catalytic subunit alpha-2 (EC 2.7.11.1) (AMPK alpha-2 chain).

CNTN3_MOUSE
θ value	1.42661e-21 (rank : 146)	NC score	0.383239 (rank : 884)
Query Neighborhood Hits	1959	Target Neighborhood Hits	447	Shared Neighborhood Hits	320
SwissProt Accessions	Q07409	Gene names	Cntn3, Pang, Pcs
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

KAPCG_HUMAN
θ value	1.86321e-21 (rank : 147)	NC score	0.851827 (rank : 147)
Query Neighborhood Hits	1959	Target Neighborhood Hits	845	Shared Neighborhood Hits	822
SwissProt Accessions	P22612, O60850, Q86YI1	Gene names	PRKACG
Domain Architecture
Description	cAMP-dependent protein kinase, gamma-catalytic subunit (EC 2.7.11.11) (PKA C-gamma).

MYPC1_HUMAN
θ value	2.43343e-21 (rank : 148)	NC score	0.364753 (rank : 897)
Query Neighborhood Hits	1959	Target Neighborhood Hits	303	Shared Neighborhood Hits	257
SwissProt Accessions	Q00872, Q15497	Gene names	MYBPC1, MYBPCS
Domain Architecture
Description	Myosin-binding protein C, slow-type (Slow MyBP-C) (C-protein, skeletal muscle slow isoform).

AURKB_HUMAN
θ value	3.17815e-21 (rank : 149)	NC score	0.865508 (rank : 49)
Query Neighborhood Hits	1959	Target Neighborhood Hits	847	Shared Neighborhood Hits	826
SwissProt Accessions	Q96GD4, O14630, O60446, O95083, Q96DV5, Q9UQ46	Gene names	AURKB, AIK2, AIM1, ARK2, STK12
Domain Architecture
Description	Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-B) (Aurora- and Ipl1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1- related kinase 2) (Aurora-related kinase 2) (STK-1).

DSCL1_HUMAN
θ value	4.15078e-21 (rank : 150)	NC score	0.397813 (rank : 851)
Query Neighborhood Hits	1959	Target Neighborhood Hits	589	Shared Neighborhood Hits	386
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

L1CAM_HUMAN
θ value	4.15078e-21 (rank : 151)	NC score	0.388443 (rank : 873)
Query Neighborhood Hits	1959	Target Neighborhood Hits	457	Shared Neighborhood Hits	331
SwissProt Accessions	P32004, Q8TA87	Gene names	L1CAM, CAML1, MIC5
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

PLK1_MOUSE
θ value	5.42112e-21 (rank : 152)	NC score	0.864313 (rank : 56)
Query Neighborhood Hits	1959	Target Neighborhood Hits	849	Shared Neighborhood Hits	820
SwissProt Accessions	Q07832	Gene names	Plk1, Plk
Domain Architecture
Description	Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13).

CDKL1_MOUSE
θ value	7.0802e-21 (rank : 153)	NC score	0.834744 (rank : 257)
Query Neighborhood Hits	1959	Target Neighborhood Hits	829	Shared Neighborhood Hits	812
SwissProt Accessions	Q8CEQ0	Gene names	Cdkl1
Domain Architecture	No domain graphic available
Description	Cyclin-dependent kinase-like 1 (EC 2.7.11.22).

PAK4_HUMAN
θ value	7.0802e-21 (rank : 154)	NC score	0.850891 (rank : 154)
Query Neighborhood Hits	1959	Target Neighborhood Hits	924	Shared Neighborhood Hits	875
SwissProt Accessions	O96013, Q8N4E1, Q8NCH5, Q8NDE3, Q9BU33, Q9ULS8	Gene names	PAK4, KIAA1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

L1CAM_MOUSE
θ value	9.24701e-21 (rank : 155)	NC score	0.387269 (rank : 876)
Query Neighborhood Hits	1959	Target Neighborhood Hits	457	Shared Neighborhood Hits	328
SwissProt Accessions	P11627	Gene names	L1cam, Caml1
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

PLK1_HUMAN
θ value	9.24701e-21 (rank : 156)	NC score	0.863476 (rank : 63)
Query Neighborhood Hits	1959	Target Neighborhood Hits	849	Shared Neighborhood Hits	821
SwissProt Accessions	P53350, Q15153, Q99746	Gene names	PLK1, PLK
Domain Architecture
Description	Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13).

PUNC_HUMAN
θ value	9.24701e-21 (rank : 157)	NC score	0.402479 (rank : 847)
Query Neighborhood Hits	1959	Target Neighborhood Hits	449	Shared Neighborhood Hits	308
SwissProt Accessions	Q8IVU1, O95215	Gene names	PUNC
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

ST38L_HUMAN
θ value	9.24701e-21 (rank : 158)	NC score	0.825063 (rank : 322)
Query Neighborhood Hits	1959	Target Neighborhood Hits	824	Shared Neighborhood Hits	790
SwissProt Accessions	Q9Y2H1, Q8TBX7	Gene names	STK38L, KIAA0965, NDR2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 38-like (EC 2.7.11.1) (NDR2 protein kinase) (Nuclear Dbf2-related kinase 2).

BOC_MOUSE
θ value	1.2077e-20 (rank : 159)	NC score	0.397707 (rank : 852)
Query Neighborhood Hits	1959	Target Neighborhood Hits	433	Shared Neighborhood Hits	320
SwissProt Accessions	Q6AZB0, Q6KAM5, Q6P5H3, Q7TMJ3, Q8CE73, Q8CE91, Q8R377, Q923W7	Gene names	Boc
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

KS6A4_MOUSE
θ value	1.2077e-20 (rank : 160)	NC score	0.846431 (rank : 180)
Query Neighborhood Hits	1959	Target Neighborhood Hits	866	Shared Neighborhood Hits	826
SwissProt Accessions	Q9Z2B9, Q91X18	Gene names	Rps6ka4, Msk2
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-4 (EC 2.7.11.1) (Nuclear mitogen- and stress-activated protein kinase 2) (90 kDa ribosomal protein S6 kinase 4) (RSK-like protein kinase) (RLSK).

ST32C_HUMAN
θ value	1.2077e-20 (rank : 161)	NC score	0.843856 (rank : 202)
Query Neighborhood Hits	1959	Target Neighborhood Hits	832	Shared Neighborhood Hits	813
SwissProt Accessions	Q86UX6, Q5T0Q5, Q86UE1	Gene names	STK32C
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 32C (EC 2.7.11.1) (PKE) (YANK3).

CDKL4_HUMAN
θ value	1.5773e-20 (rank : 162)	NC score	0.831211 (rank : 279)
Query Neighborhood Hits	1959	Target Neighborhood Hits	828	Shared Neighborhood Hits	810
SwissProt Accessions	Q5MAI5	Gene names	CDKL4
Domain Architecture	No domain graphic available
Description	Cyclin-dependent kinase-like 4 (EC 2.7.11.22).

DSCAM_HUMAN
θ value	1.5773e-20 (rank : 163)	NC score	0.394961 (rank : 858)
Query Neighborhood Hits	1959	Target Neighborhood Hits	524	Shared Neighborhood Hits	347
SwissProt Accessions	O60469, O60468	Gene names	DSCAM
Domain Architecture
Description	Down syndrome cell adhesion molecule precursor (CHD2).

CNTN3_HUMAN
θ value	2.06002e-20 (rank : 164)	NC score	0.386320 (rank : 878)
Query Neighborhood Hits	1959	Target Neighborhood Hits	455	Shared Neighborhood Hits	325
SwissProt Accessions	Q9P232, Q9H039	Gene names	CNTN3, KIAA1496, PANG
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

KKCC1_HUMAN
θ value	2.06002e-20 (rank : 165)	NC score	0.862451 (rank : 71)
Query Neighborhood Hits	1959	Target Neighborhood Hits	858	Shared Neighborhood Hits	831
SwissProt Accessions	Q8N5S9, Q9BQH3	Gene names	CAMKK1, CAMKKA
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase kinase 1 (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-kinase kinase alpha) (CaM-KK alpha) (CaMKK alpha) (CaMKK 1) (CaM-kinase IV kinase).

KS6A4_HUMAN
θ value	2.06002e-20 (rank : 166)	NC score	0.846369 (rank : 181)
Query Neighborhood Hits	1959	Target Neighborhood Hits	868	Shared Neighborhood Hits	829
SwissProt Accessions	O75676, O75585, Q53ES8	Gene names	RPS6KA4, MSK2
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-4 (EC 2.7.11.1) (Nuclear mitogen- and stress-activated protein kinase 2) (90 kDa ribosomal protein S6 kinase 4) (Ribosomal protein kinase B) (RSKB).

KS6A5_MOUSE
θ value	2.06002e-20 (rank : 167)	NC score	0.843367 (rank : 206)
Query Neighborhood Hits	1959	Target Neighborhood Hits	854	Shared Neighborhood Hits	823
SwissProt Accessions	Q8C050, Q8CI92	Gene names	Rps6ka5, Msk1
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear mitogen- and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RLSK).

AAPK1_HUMAN
θ value	2.69047e-20 (rank : 168)	NC score	0.860907 (rank : 80)
Query Neighborhood Hits	1959	Target Neighborhood Hits	842	Shared Neighborhood Hits	824
SwissProt Accessions	Q13131, O00286, Q5D0E1, Q9UNQ4	Gene names	PRKAA1, AMPK1
Domain Architecture
Description	5'-AMP-activated protein kinase catalytic subunit alpha-1 (EC 2.7.11.1) (AMPK alpha-1 chain).

AAPK1_MOUSE
θ value	2.69047e-20 (rank : 169)	NC score	0.860738 (rank : 81)
Query Neighborhood Hits	1959	Target Neighborhood Hits	843	Shared Neighborhood Hits	824
SwissProt Accessions	Q5EG47	Gene names	Prkaa1
Domain Architecture	No domain graphic available
Description	5'-AMP-activated protein kinase catalytic subunit alpha-1 (EC 2.7.11.1) (AMPK alpha-1 chain).

CDKL4_MOUSE
θ value	2.69047e-20 (rank : 170)	NC score	0.833536 (rank : 266)
Query Neighborhood Hits	1959	Target Neighborhood Hits	833	Shared Neighborhood Hits	814
SwissProt Accessions	Q3TZA2	Gene names	Cdkl4
Domain Architecture	No domain graphic available
Description	Cyclin-dependent kinase-like 4 (EC 2.7.11.22).

KGP1A_HUMAN
θ value	2.69047e-20 (rank : 171)	NC score	0.837293 (rank : 235)
Query Neighborhood Hits	1959	Target Neighborhood Hits	901	Shared Neighborhood Hits	822
SwissProt Accessions	Q13976	Gene names	PRKG1, PRKGR1A
Domain Architecture
Description	cGMP-dependent protein kinase 1, alpha isozyme (EC 2.7.11.12) (CGK 1 alpha) (cGKI-alpha).

KGP1B_HUMAN
θ value	2.69047e-20 (rank : 172)	NC score	0.836903 (rank : 242)
Query Neighborhood Hits	1959	Target Neighborhood Hits	921	Shared Neighborhood Hits	825
SwissProt Accessions	P14619	Gene names	PRKG1, PRKG1B, PRKGR1B
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KGP1B_MOUSE
θ value	2.69047e-20 (rank : 173)	NC score	0.836970 (rank : 241)
Query Neighborhood Hits	1959	Target Neighborhood Hits	922	Shared Neighborhood Hits	825
SwissProt Accessions	Q9Z0Z0	Gene names	Prkg1, Prkg1b, Prkgr1b
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KKCC1_MOUSE
θ value	3.51386e-20 (rank : 174)	NC score	0.862459 (rank : 70)
Query Neighborhood Hits	1959	Target Neighborhood Hits	866	Shared Neighborhood Hits	838
SwissProt Accessions	Q8VBY2, Q9R054	Gene names	Camkk1, Camkk
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase kinase 1 (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-kinase kinase alpha) (CaM-KK alpha) (CaMKK alpha) (CaMKK 1) (CaM-kinase IV kinase).

PRKX_MOUSE
θ value	3.51386e-20 (rank : 175)	NC score	0.851629 (rank : 148)
Query Neighborhood Hits	1959	Target Neighborhood Hits	846	Shared Neighborhood Hits	824
SwissProt Accessions	Q922R0, Q3UCD1, Q8BHD6, Q9QZ12	Gene names	Prkx, Pkare
Domain Architecture
Description	Serine/threonine-protein kinase PRKX (EC 2.7.11.1) (PKA-related protein kinase).

CDKL1_HUMAN
θ value	4.58923e-20 (rank : 176)	NC score	0.834224 (rank : 263)
Query Neighborhood Hits	1959	Target Neighborhood Hits	830	Shared Neighborhood Hits	813
SwissProt Accessions	Q00532, Q6QUA0	Gene names	CDKL1
Domain Architecture
Description	Cyclin-dependent kinase-like 1 (EC 2.7.11.22) (Serine/threonine- protein kinase KKIALRE) (Protein kinase p42 KKIALRE).

M3K6_HUMAN
θ value	4.58923e-20 (rank : 177)	NC score	0.843996 (rank : 199)
Query Neighborhood Hits	1959	Target Neighborhood Hits	889	Shared Neighborhood Hits	837
SwissProt Accessions	O95382	Gene names	MAP3K6, MAPKKK6
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 6 (EC 2.7.11.25).

NEK3_MOUSE
θ value	4.58923e-20 (rank : 178)	NC score	0.852834 (rank : 140)
Query Neighborhood Hits	1959	Target Neighborhood Hits	854	Shared Neighborhood Hits	826
SwissProt Accessions	Q9R0A5, Q9Z0X9	Gene names	Nek3
Domain Architecture
Description	Serine/threonine-protein kinase Nek3 (EC 2.7.11.1) (NimA-related protein kinase 3).

NRCAM_MOUSE
θ value	4.58923e-20 (rank : 179)	NC score	0.385826 (rank : 880)
Query Neighborhood Hits	1959	Target Neighborhood Hits	432	Shared Neighborhood Hits	325
SwissProt Accessions	Q810U4, Q80U33, Q8BLG8, Q8BX92, Q8BYJ8	Gene names	Nrcam, Kiaa0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (mBravo).

STK3_HUMAN
θ value	4.58923e-20 (rank : 180)	NC score	0.834886 (rank : 255)
Query Neighborhood Hits	1959	Target Neighborhood Hits	861	Shared Neighborhood Hits	821
SwissProt Accessions	Q13188, Q15445, Q15801, Q96FM6	Gene names	STK3, MST2
Domain Architecture
Description	Serine/threonine-protein kinase 3 (EC 2.7.11.1) (STE20-like kinase MST2) (MST-2) (Mammalian STE20-like protein kinase 2) (Serine/threonine-protein kinase Krs-1).

STK4_HUMAN
θ value	4.58923e-20 (rank : 181)	NC score	0.834935 (rank : 253)
Query Neighborhood Hits	1959	Target Neighborhood Hits	870	Shared Neighborhood Hits	824
SwissProt Accessions	Q13043, Q15802, Q4G156, Q5H982, Q6PD60, Q9BR32, Q9NTZ4	Gene names	STK4, MST1
Domain Architecture
Description	Serine/threonine-protein kinase 4 (EC 2.7.11.1) (STE20-like kinase MST1) (MST-1) (Mammalian STE20-like protein kinase 1) (Serine/threonine-protein kinase Krs-2).

PRKX_HUMAN
θ value	5.99374e-20 (rank : 182)	NC score	0.851367 (rank : 151)
Query Neighborhood Hits	1959	Target Neighborhood Hits	847	Shared Neighborhood Hits	822
SwissProt Accessions	P51817	Gene names	PRKX, PKX1
Domain Architecture
Description	Serine/threonine-protein kinase PRKX (EC 2.7.11.1) (Protein kinase PKX1).

CNTN1_MOUSE
θ value	7.82807e-20 (rank : 183)	NC score	0.383716 (rank : 883)
Query Neighborhood Hits	1959	Target Neighborhood Hits	422	Shared Neighborhood Hits	316
SwissProt Accessions	P12960, Q6NXV7, Q8BR42, Q8C6A0	Gene names	Cntn1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3).

CNTN5_MOUSE
θ value	1.02238e-19 (rank : 184)	NC score	0.388772 (rank : 870)
Query Neighborhood Hits	1959	Target Neighborhood Hits	434	Shared Neighborhood Hits	332
SwissProt Accessions	P68500	Gene names	Cntn5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2).

ROBO3_MOUSE
θ value	1.02238e-19 (rank : 185)	NC score	0.404887 (rank : 845)
Query Neighborhood Hits	1959	Target Neighborhood Hits	524	Shared Neighborhood Hits	370
SwissProt Accessions	Q9Z2I4	Gene names	Robo3, Rbig1
Domain Architecture
Description	Roundabout homolog 3 precursor (Retinoblastoma-inhibiting gene 1) (Rig-1).

ST32C_MOUSE
θ value	1.02238e-19 (rank : 186)	NC score	0.845562 (rank : 186)
Query Neighborhood Hits	1959	Target Neighborhood Hits	824	Shared Neighborhood Hits	809
SwissProt Accessions	Q8QZV4, Q9JJG4	Gene names	Stk32c, Pkek
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 32C (EC 2.7.11.1).

MAPK3_MOUSE
θ value	1.74391e-19 (rank : 187)	NC score	0.859262 (rank : 93)
Query Neighborhood Hits	1959	Target Neighborhood Hits	811	Shared Neighborhood Hits	795
SwissProt Accessions	Q3UMW7, Q3T9E6, Q8K0G3	Gene names	Mapkapk3
Domain Architecture	No domain graphic available
Description	MAP kinase-activated protein kinase 3 (EC 2.7.11.1) (MAPK-activated protein kinase 3) (MAPKAP kinase 3) (MAPKAPK-3).

STK3_MOUSE
θ value	1.74391e-19 (rank : 188)	NC score	0.835209 (rank : 249)
Query Neighborhood Hits	1959	Target Neighborhood Hits	869	Shared Neighborhood Hits	821
SwissProt Accessions	Q9JI10, Q60877, Q80UG4, Q8CI58	Gene names	Stk3, Mess1, Mst2
Domain Architecture
Description	Serine/threonine-protein kinase 3 (EC 2.7.11.1) (STE20-like kinase MST2) (MST-2) (Mammalian STE20-like protein kinase 2).

MKNK1_MOUSE
θ value	2.27762e-19 (rank : 189)	NC score	0.852888 (rank : 138)
Query Neighborhood Hits	1959	Target Neighborhood Hits	811	Shared Neighborhood Hits	790
SwissProt Accessions	O08605	Gene names	Mknk1, Mnk1
Domain Architecture
Description	MAP kinase-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (Mnk1).

STK4_MOUSE
θ value	2.27762e-19 (rank : 190)	NC score	0.834955 (rank : 252)
Query Neighborhood Hits	1959	Target Neighborhood Hits	873	Shared Neighborhood Hits	824
SwissProt Accessions	Q9JI11	Gene names	Stk4, Mst1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 4 (EC 2.7.11.1) (STE20-like kinase MST1) (MST-1) (Mammalian STE20-like protein kinase 1).

M3K3_HUMAN
θ value	2.97466e-19 (rank : 191)	NC score	0.846748 (rank : 176)
Query Neighborhood Hits	1959	Target Neighborhood Hits	885	Shared Neighborhood Hits	835
SwissProt Accessions	Q99759	Gene names	MAP3K3, MAPKKK3, MEKK3
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3).

MAPK3_HUMAN
θ value	2.97466e-19 (rank : 192)	NC score	0.858929 (rank : 95)
Query Neighborhood Hits	1959	Target Neighborhood Hits	807	Shared Neighborhood Hits	787
SwissProt Accessions	Q16644	Gene names	MAPKAPK3
Domain Architecture	No domain graphic available
Description	MAP kinase-activated protein kinase 3 (EC 2.7.11.1) (MAPK-activated protein kinase 3) (MAPKAP kinase 3) (MAPKAPK-3) (Chromosome 3p kinase) (3pK).

NCAM2_MOUSE
θ value	2.97466e-19 (rank : 193)	NC score	0.395579 (rank : 855)
Query Neighborhood Hits	1959	Target Neighborhood Hits	472	Shared Neighborhood Hits	332
SwissProt Accessions	O35136, O35962	Gene names	Ncam2, Ocam, Rncam
Domain Architecture
Description	Neural cell adhesion molecule 2 precursor (N-CAM 2) (RB-8 neural cell adhesion molecule) (R4B12).

ST38L_MOUSE
θ value	2.97466e-19 (rank : 194)	NC score	0.818944 (rank : 353)
Query Neighborhood Hits	1959	Target Neighborhood Hits	821	Shared Neighborhood Hits	788
SwissProt Accessions	Q7TSE6, Q6P6K6, Q8BWK4	Gene names	Stk38l, Ndr2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 38-like (EC 2.7.11.1) (NDR2 protein kinase) (Nuclear Dbf2-related kinase 2).

CNTN1_HUMAN
θ value	5.07402e-19 (rank : 195)	NC score	0.383183 (rank : 885)
Query Neighborhood Hits	1959	Target Neighborhood Hits	431	Shared Neighborhood Hits	316
SwissProt Accessions	Q12860, Q12861, Q14030, Q8N466	Gene names	CNTN1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3) (Glycoprotein gp135).

M3K3_MOUSE
θ value	5.07402e-19 (rank : 196)	NC score	0.846903 (rank : 174)
Query Neighborhood Hits	1959	Target Neighborhood Hits	876	Shared Neighborhood Hits	834
SwissProt Accessions	Q61084	Gene names	Map3k3, Mekk3
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3).

NEK3_HUMAN
θ value	5.07402e-19 (rank : 197)	NC score	0.850817 (rank : 155)
Query Neighborhood Hits	1959	Target Neighborhood Hits	865	Shared Neighborhood Hits	826
SwissProt Accessions	P51956, Q8WUN5	Gene names	NEK3
Domain Architecture
Description	Serine/threonine-protein kinase Nek3 (EC 2.7.11.1) (NimA-related protein kinase 3) (HSPK 36).

KS6B2_MOUSE
θ value	6.62687e-19 (rank : 198)	NC score	0.845148 (rank : 190)
Query Neighborhood Hits	1959	Target Neighborhood Hits	871	Shared Neighborhood Hits	835
SwissProt Accessions	Q9Z1M4	Gene names	Rps6kb2
Domain Architecture
Description	Ribosomal protein S6 kinase beta-2 (EC 2.7.11.1) (S6K-beta 2) (70 kDa ribosomal protein S6 kinase 2) (p70-S6KB) (p70 ribosomal S6 kinase beta) (p70 S6Kbeta) (S6K2).

MUSK_HUMAN
θ value	6.62687e-19 (rank : 199)	NC score	0.736245 (rank : 564)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1074	Shared Neighborhood Hits	1002
SwissProt Accessions	O15146	Gene names	MUSK
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (Muscle-specific kinase receptor) (MuSK).

MAPK2_HUMAN
θ value	8.65492e-19 (rank : 200)	NC score	0.861490 (rank : 77)
Query Neighborhood Hits	1959	Target Neighborhood Hits	844	Shared Neighborhood Hits	816
SwissProt Accessions	P49137, Q8IYD6	Gene names	MAPKAPK2
Domain Architecture
Description	MAP kinase-activated protein kinase 2 (EC 2.7.11.1) (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAPK-2) (MK2).

PUNC_MOUSE
θ value	8.65492e-19 (rank : 201)	NC score	0.402941 (rank : 846)
Query Neighborhood Hits	1959	Target Neighborhood Hits	501	Shared Neighborhood Hits	348
SwissProt Accessions	Q8BQC3, O70246, Q792T2, Q9Z2S6	Gene names	Punc
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

KAPCA_HUMAN
θ value	1.13037e-18 (rank : 202)	NC score	0.848639 (rank : 162)
Query Neighborhood Hits	1959	Target Neighborhood Hits	838	Shared Neighborhood Hits	820
SwissProt Accessions	P17612, Q9H2Y0, Q9NRB4, Q9NRH9	Gene names	PRKACA, PKACA
Domain Architecture
Description	cAMP-dependent protein kinase, alpha-catalytic subunit (EC 2.7.11.11) (PKA C-alpha).

KAPCB_HUMAN
θ value	1.13037e-18 (rank : 203)	NC score	0.848046 (rank : 167)
Query Neighborhood Hits	1959	Target Neighborhood Hits	837	Shared Neighborhood Hits	821
SwissProt Accessions	P22694, Q59GC0, Q5BNE9, Q5BNF0, Q5BNF1, Q5BNF2, Q5BNF3, Q5CZ92, Q5T1K3, Q7Z3M1, Q8IYR5, Q8IZQ0	Gene names	PRKACB
Domain Architecture
Description	cAMP-dependent protein kinase, beta-catalytic subunit (EC 2.7.11.11) (PKA C-beta).

KKCC2_HUMAN
θ value	1.13037e-18 (rank : 204)	NC score	0.861630 (rank : 76)
Query Neighborhood Hits	1959	Target Neighborhood Hits	852	Shared Neighborhood Hits	820
SwissProt Accessions	Q96RR4, O94883, Q8IUG2, Q8IUG3, Q8N3I4, Q8WY03, Q8WY04, Q8WY05, Q8WY06, Q96RP1, Q96RP2, Q96RR3, Q9BWE9, Q9UER3, Q9UES2, Q9Y5N2	Gene names	CAMKK2, CAMKKB, KIAA0787
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase kinase 2 (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta).

KKCC2_MOUSE
θ value	1.13037e-18 (rank : 205)	NC score	0.861729 (rank : 74)
Query Neighborhood Hits	1959	Target Neighborhood Hits	855	Shared Neighborhood Hits	819
SwissProt Accessions	Q8C078, Q80TS0, Q8BXM8, Q8C0G3, Q8CH42, Q8QZT7	Gene names	Camkk2, Kiaa0787
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase kinase 2 (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta).

KS6B1_HUMAN
θ value	1.13037e-18 (rank : 206)	NC score	0.846548 (rank : 178)
Query Neighborhood Hits	1959	Target Neighborhood Hits	850	Shared Neighborhood Hits	821
SwissProt Accessions	P23443	Gene names	RPS6KB1
Domain Architecture
Description	Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1) (Ribosomal protein S6 kinase I) (S6K) (S6K1) (70 kDa ribosomal protein S6 kinase 1) (p70 S6 kinase alpha) (p70(S6K)-alpha) (p70-S6K) (P70S6K) (p70-alpha).

KS6B1_MOUSE
θ value	1.13037e-18 (rank : 207)	NC score	0.846556 (rank : 177)
Query Neighborhood Hits	1959	Target Neighborhood Hits	849	Shared Neighborhood Hits	821
SwissProt Accessions	Q8BSK8, Q8CHX0	Gene names	Rps6kb1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1) (Ribosomal protein S6 kinase I) (S6K) (S6K1) (70 kDa ribosomal protein S6 kinase 1) (p70 S6 kinase alpha) (p70(S6K)-alpha) (p70-S6K) (P70S6K).

MARK3_HUMAN
θ value	1.13037e-18 (rank : 208)	NC score	0.851586 (rank : 149)
Query Neighborhood Hits	1959	Target Neighborhood Hits	893	Shared Neighborhood Hits	831
SwissProt Accessions	P27448, O60219, Q8TB41, Q8WX83, Q96RG1, Q9UMY9, Q9UN34	Gene names	MARK3, CTAK1
Domain Architecture
Description	MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (Cdc25C- associated protein kinase 1) (cTAK1) (C-TAK1) (Serine/threonine protein kinase p78) (Ser/Thr protein kinase PAR-1) (Protein kinase STK10).

PDPK1_MOUSE
θ value	1.13037e-18 (rank : 209)	NC score	0.856713 (rank : 117)
Query Neighborhood Hits	1959	Target Neighborhood Hits	852	Shared Neighborhood Hits	825
SwissProt Accessions	Q9Z2A0, Q9R1D8, Q9R215	Gene names	Pdpk1, Pdk1
Domain Architecture
Description	3-phosphoinositide-dependent protein kinase 1 (EC 2.7.11.1) (mPDK1).

PKN3_MOUSE
θ value	1.13037e-18 (rank : 210)	NC score	0.834545 (rank : 260)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1009	Shared Neighborhood Hits	877
SwissProt Accessions	Q8K045	Gene names	Pkn3, Pknbeta
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

SGK3_MOUSE
θ value	1.47631e-18 (rank : 211)	NC score	0.838244 (rank : 229)
Query Neighborhood Hits	1959	Target Neighborhood Hits	882	Shared Neighborhood Hits	817
SwissProt Accessions	Q9ERE3, Q3UAY2	Gene names	Sgk3, Cisk, Sgkl
Domain Architecture
Description	Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid- regulated kinase-like) (Cytokine-independent survival kinase).

IKKA_MOUSE
θ value	1.92812e-18 (rank : 212)	NC score	0.845398 (rank : 188)
Query Neighborhood Hits	1959	Target Neighborhood Hits	867	Shared Neighborhood Hits	820
SwissProt Accessions	Q60680, Q80VU2, Q9D2X3	Gene names	Chuk, Ikka
Domain Architecture
Description	Inhibitor of nuclear factor kappa-B kinase alpha subunit (EC 2.7.11.10) (I kappa-B kinase alpha) (IkBKA) (IKK-alpha) (IKK-A) (IkappaB kinase) (I-kappa-B kinase 1) (IKK1) (Conserved helix-loop- helix ubiquitous kinase) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA).

KAPCA_MOUSE
θ value	1.92812e-18 (rank : 213)	NC score	0.848917 (rank : 161)
Query Neighborhood Hits	1959	Target Neighborhood Hits	836	Shared Neighborhood Hits	820
SwissProt Accessions	P05132, Q9JID0	Gene names	Prkaca, Pkaca
Domain Architecture
Description	cAMP-dependent protein kinase, alpha-catalytic subunit (EC 2.7.11.11) (PKA C-alpha).

KS6B2_HUMAN
θ value	1.92812e-18 (rank : 214)	NC score	0.846540 (rank : 179)
Query Neighborhood Hits	1959	Target Neighborhood Hits	858	Shared Neighborhood Hits	834
SwissProt Accessions	Q9UBS0, O94809, Q9UEC1	Gene names	RPS6KB2, STK14B
Domain Architecture
Description	Ribosomal protein S6 kinase beta-2 (EC 2.7.11.1) (S6K2) (70 kDa ribosomal protein S6 kinase 2) (p70-S6KB) (p70 ribosomal S6 kinase beta) (p70 S6Kbeta) (p70 S6 kinase beta) (S6K-beta) (p70-beta) (S6 kinase-related kinase) (SRK) (Serine/threonine-protein kinase 14 beta).

MAPK2_MOUSE
θ value	1.92812e-18 (rank : 215)	NC score	0.861119 (rank : 79)
Query Neighborhood Hits	1959	Target Neighborhood Hits	831	Shared Neighborhood Hits	807
SwissProt Accessions	P49138, Q6P561	Gene names	Mapkapk2, Rps6kc1
Domain Architecture	No domain graphic available
Description	MAP kinase-activated protein kinase 2 (EC 2.7.11.1) (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAPK-2) (MK2).

MYPC2_HUMAN
θ value	1.92812e-18 (rank : 216)	NC score	0.357904 (rank : 903)
Query Neighborhood Hits	1959	Target Neighborhood Hits	316	Shared Neighborhood Hits	263
SwissProt Accessions	Q14324	Gene names	MYBPC2, MYBPCF
Domain Architecture
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

PRKY_HUMAN
θ value	1.92812e-18 (rank : 217)	NC score	0.856545 (rank : 118)
Query Neighborhood Hits	1959	Target Neighborhood Hits	844	Shared Neighborhood Hits	822
SwissProt Accessions	O43930, O15348, O15349	Gene names	PRKY
Domain Architecture
Description	Serine/threonine-protein kinase PRKY (EC 2.7.11.1).

PTK7_HUMAN
θ value	1.92812e-18 (rank : 218)	NC score	0.766238 (rank : 528)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1103	Shared Neighborhood Hits	998
SwissProt Accessions	Q13308, Q13417	Gene names	PTK7, CCK4
Domain Architecture
Description	Tyrosine-protein kinase-like 7 precursor (Colon carcinoma kinase 4) (CCK-4).

ST32A_MOUSE
θ value	1.92812e-18 (rank : 219)	NC score	0.846829 (rank : 175)
Query Neighborhood Hits	1959	Target Neighborhood Hits	833	Shared Neighborhood Hits	813
SwissProt Accessions	Q8BGW6, Q7TPQ4	Gene names	Stk32a
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 32A (EC 2.7.11.1).

STK24_HUMAN
θ value	1.92812e-18 (rank : 220)	NC score	0.831369 (rank : 278)
Query Neighborhood Hits	1959	Target Neighborhood Hits	853	Shared Neighborhood Hits	826
SwissProt Accessions	Q9Y6E0, O14840	Gene names	STK24, MST3, STK3
Domain Architecture
Description	Serine/threonine-protein kinase 24 (EC 2.7.11.1) (STE20-like kinase MST3) (MST-3) (Mammalian STE20-like protein kinase 3).

KAPCB_MOUSE
θ value	3.28887e-18 (rank : 221)	NC score	0.847804 (rank : 168)
Query Neighborhood Hits	1959	Target Neighborhood Hits	836	Shared Neighborhood Hits	821
SwissProt Accessions	P68181, P05206, Q3TQH5, Q3UDD0, Q3UTH5	Gene names	Prkacb, Pkacb
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase, beta-catalytic subunit (EC 2.7.11.11) (PKA C-beta).

KPCA_HUMAN
θ value	3.28887e-18 (rank : 222)	NC score	0.811523 (rank : 386)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1070	Shared Neighborhood Hits	821
SwissProt Accessions	P17252, Q15137, Q96RE4	Gene names	PRKCA, PKCA, PRKACA
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

PDPK1_HUMAN
θ value	3.28887e-18 (rank : 223)	NC score	0.857077 (rank : 113)
Query Neighborhood Hits	1959	Target Neighborhood Hits	851	Shared Neighborhood Hits	825
SwissProt Accessions	O15530	Gene names	PDPK1, PDK1
Domain Architecture
Description	3-phosphoinositide-dependent protein kinase 1 (EC 2.7.11.1) (hPDK1).

PKN1_HUMAN
θ value	3.28887e-18 (rank : 224)	NC score	0.832917 (rank : 270)
Query Neighborhood Hits	1959	Target Neighborhood Hits	886	Shared Neighborhood Hits	828
SwissProt Accessions	Q16512, Q15143, Q8IUV5	Gene names	PKN1, PKN, PRK1, PRKCL1
Domain Architecture
Description	Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protein kinase C- like 1) (Protein-kinase C-related kinase 1) (Protein kinase C-like PKN) (Serine-threonine protein kinase N) (Protein kinase PKN-alpha).

PKN1_MOUSE
θ value	3.28887e-18 (rank : 225)	NC score	0.833210 (rank : 267)
Query Neighborhood Hits	1959	Target Neighborhood Hits	888	Shared Neighborhood Hits	821
SwissProt Accessions	P70268, Q7TST2	Gene names	Pkn1, Pkn, Prk1, Prkcl1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protein kinase C- like 1) (Protein-kinase C-related kinase 1) (Protein kinase C-like PKN) (Serine-threonine protein kinase N).

MAPK5_HUMAN
θ value	4.29542e-18 (rank : 226)	NC score	0.843556 (rank : 204)
Query Neighborhood Hits	1959	Target Neighborhood Hits	795	Shared Neighborhood Hits	775
SwissProt Accessions	Q8IW41, O60491, Q86X46, Q9BVX9, Q9UG86	Gene names	MAPKAPK5, PRAK
Domain Architecture	No domain graphic available
Description	MAP kinase-activated protein kinase 5 (EC 2.7.11.1) (MAPK-activated protein kinase 5) (MAPKAP kinase 5) (p38-regulated/activated protein kinase).

BOC_HUMAN
θ value	5.60996e-18 (rank : 227)	NC score	0.395793 (rank : 854)
Query Neighborhood Hits	1959	Target Neighborhood Hits	543	Shared Neighborhood Hits	353
SwissProt Accessions	Q9BWV1, Q6UXJ5, Q8N2P7, Q8NF26	Gene names	BOC
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

CHK1_HUMAN
θ value	5.60996e-18 (rank : 228)	NC score	0.860198 (rank : 86)
Query Neighborhood Hits	1959	Target Neighborhood Hits	843	Shared Neighborhood Hits	817
SwissProt Accessions	O14757	Gene names	CHEK1, CHK1
Domain Architecture
Description	Serine/threonine-protein kinase Chk1 (EC 2.7.11.1).

MAPK5_MOUSE
θ value	5.60996e-18 (rank : 229)	NC score	0.844793 (rank : 193)
Query Neighborhood Hits	1959	Target Neighborhood Hits	799	Shared Neighborhood Hits	779
SwissProt Accessions	O54992, Q6QME4, Q6QME5, Q6QME6, Q6QME7	Gene names	Mapkapk5
Domain Architecture	No domain graphic available
Description	MAP kinase-activated protein kinase 5 (EC 2.7.11.1) (MAPK-activated protein kinase 5) (MAPKAP kinase 5).

MUSK_MOUSE
θ value	5.60996e-18 (rank : 230)	NC score	0.733086 (rank : 571)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1057	Shared Neighborhood Hits	992
SwissProt Accessions	Q61006, Q61005, Q61987, Q61988	Gene names	Musk, Nsk2
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific kinase receptor) (MuSK).

NIM1_HUMAN
θ value	5.60996e-18 (rank : 231)	NC score	0.857810 (rank : 104)
Query Neighborhood Hits	1959	Target Neighborhood Hits	850	Shared Neighborhood Hits	820
SwissProt Accessions	Q8IY84	Gene names	NIM1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase NIM1 (EC 2.7.11.1).

IKKA_HUMAN
θ value	7.32683e-18 (rank : 232)	NC score	0.843396 (rank : 205)
Query Neighborhood Hits	1959	Target Neighborhood Hits	863	Shared Neighborhood Hits	819
SwissProt Accessions	O15111, O14666, Q13132, Q92467	Gene names	CHUK, IKKA
Domain Architecture
Description	Inhibitor of nuclear factor kappa-B kinase alpha subunit (EC 2.7.11.10) (I kappa-B kinase alpha) (IkBKA) (IKK-alpha) (IKK-A) (IkappaB kinase) (I-kappa-B kinase 1) (IKK1) (Conserved helix-loop- helix ubiquitous kinase) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA).

MK01_HUMAN
θ value	7.32683e-18 (rank : 233)	NC score	0.803754 (rank : 435)
Query Neighborhood Hits	1959	Target Neighborhood Hits	836	Shared Neighborhood Hits	816
SwissProt Accessions	P28482	Gene names	MAPK1, ERK2, PRKM1
Domain Architecture
Description	Mitogen-activated protein kinase 1 (EC 2.7.11.24) (Extracellular signal-regulated kinase 2) (ERK-2) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2) (p42-MAPK) (ERT1).

SGK2_HUMAN
θ value	7.32683e-18 (rank : 234)	NC score	0.843982 (rank : 201)
Query Neighborhood Hits	1959	Target Neighborhood Hits	840	Shared Neighborhood Hits	817
SwissProt Accessions	Q9HBY8, Q9UKG6	Gene names	SGK2
Domain Architecture
Description	Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 2).

ST32A_HUMAN
θ value	7.32683e-18 (rank : 235)	NC score	0.846321 (rank : 182)
Query Neighborhood Hits	1959	Target Neighborhood Hits	834	Shared Neighborhood Hits	816
SwissProt Accessions	Q8WU08	Gene names	STK32A
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 32A (EC 2.7.11.1) (YANK1).

LRIG1_HUMAN
θ value	9.56915e-18 (rank : 236)	NC score	0.283999 (rank : 960)
Query Neighborhood Hits	1959	Target Neighborhood Hits	654	Shared Neighborhood Hits	309
SwissProt Accessions	Q96JA1, Q6IQ51, Q96CF9, Q9BYB8, Q9UFI4	Gene names	LRIG1, LIG1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

MK01_MOUSE
θ value	9.56915e-18 (rank : 237)	NC score	0.803524 (rank : 436)
Query Neighborhood Hits	1959	Target Neighborhood Hits	836	Shared Neighborhood Hits	816
SwissProt Accessions	P63085, P27703, Q3V1U6	Gene names	Mapk1, Erk2, Mapk, Prkm1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 1 (EC 2.7.11.24) (Extracellular signal-regulated kinase 2) (ERK-2) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2) (p42-MAPK) (ERT1).

MYPC3_MOUSE
θ value	9.56915e-18 (rank : 238)	NC score	0.350953 (rank : 911)
Query Neighborhood Hits	1959	Target Neighborhood Hits	310	Shared Neighborhood Hits	260
SwissProt Accessions	O70468, O88997	Gene names	Mybpc3
Domain Architecture
Description	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform).

ROCK1_HUMAN
θ value	9.56915e-18 (rank : 239)	NC score	0.733702 (rank : 570)
Query Neighborhood Hits	1959	Target Neighborhood Hits	2000	Shared Neighborhood Hits	914
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

ROCK1_MOUSE
θ value	9.56915e-18 (rank : 240)	NC score	0.719094 (rank : 591)
Query Neighborhood Hits	1959	Target Neighborhood Hits	2126	Shared Neighborhood Hits	925
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

SDK1_HUMAN
θ value	9.56915e-18 (rank : 241)	NC score	0.382347 (rank : 887)
Query Neighborhood Hits	1959	Target Neighborhood Hits	511	Shared Neighborhood Hits	353
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

SGK2_MOUSE
θ value	9.56915e-18 (rank : 242)	NC score	0.843725 (rank : 203)
Query Neighborhood Hits	1959	Target Neighborhood Hits	833	Shared Neighborhood Hits	815
SwissProt Accessions	Q9QZS5, Q8R0P6	Gene names	Sgk2
Domain Architecture
Description	Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 2).

CDK2_HUMAN
θ value	1.24977e-17 (rank : 243)	NC score	0.821290 (rank : 342)
Query Neighborhood Hits	1959	Target Neighborhood Hits	832	Shared Neighborhood Hits	814
SwissProt Accessions	P24941	Gene names	CDK2
Domain Architecture
Description	Cell division protein kinase 2 (EC 2.7.11.22) (p33 protein kinase).

KGP2_MOUSE
θ value	1.24977e-17 (rank : 244)	NC score	0.836881 (rank : 243)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1029	Shared Neighborhood Hits	831
SwissProt Accessions	Q61410	Gene names	Prkg2, Prkgr2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

SGK3_HUMAN
θ value	1.24977e-17 (rank : 245)	NC score	0.837854 (rank : 231)
Query Neighborhood Hits	1959	Target Neighborhood Hits	877	Shared Neighborhood Hits	817
SwissProt Accessions	Q96BR1, Q9P1Q7, Q9UKG5	Gene names	SGK3, SGKL
Domain Architecture
Description	Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid- regulated kinase-like).

ULK1_HUMAN
θ value	1.24977e-17 (rank : 246)	NC score	0.857943 (rank : 102)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1121	Shared Neighborhood Hits	934
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).

KGP2_HUMAN
θ value	1.63225e-17 (rank : 247)	NC score	0.837226 (rank : 236)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1023	Shared Neighborhood Hits	832
SwissProt Accessions	Q13237, O00125, O60916	Gene names	PRKG2, PRKGR2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

KPCB_HUMAN
θ value	1.63225e-17 (rank : 248)	NC score	0.805395 (rank : 424)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1121	Shared Neighborhood Hits	821
SwissProt Accessions	P05771, O43744, P05127, Q15138, Q93060, Q9UE49, Q9UE50, Q9UEH8, Q9UJ30, Q9UJ33	Gene names	PRKCB1, PKCB, PRKCB
Domain Architecture
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

KPCB_MOUSE
θ value	1.63225e-17 (rank : 249)	NC score	0.805842 (rank : 419)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1117	Shared Neighborhood Hits	820
SwissProt Accessions	P68404, P04410, P04411	Gene names	Prkcb1, Pkcb, Prkcb
Domain Architecture	No domain graphic available
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

KPCG_HUMAN
θ value	1.63225e-17 (rank : 250)	NC score	0.806022 (rank : 418)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1126	Shared Neighborhood Hits	823
SwissProt Accessions	P05129	Gene names	PRKCG, PKCG
Domain Architecture
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

KPCG_MOUSE
θ value	2.13179e-17 (rank : 251)	NC score	0.806259 (rank : 415)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1123	Shared Neighborhood Hits	823
SwissProt Accessions	P63318, P05697	Gene names	Prkcg, Pkcc, Pkcg, Prkcc
Domain Architecture	No domain graphic available
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

MRCKG_HUMAN
θ value	2.13179e-17 (rank : 252)	NC score	0.785921 (rank : 486)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1519	Shared Neighborhood Hits	878
SwissProt Accessions	Q6DT37, O00565	Gene names	CDC42BPG
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

STK38_MOUSE
θ value	2.13179e-17 (rank : 253)	NC score	0.823557 (rank : 331)
Query Neighborhood Hits	1959	Target Neighborhood Hits	838	Shared Neighborhood Hits	796
SwissProt Accessions	Q91VJ4	Gene names	Stk38, Ndr1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1 protein kinase) (Nuclear Dbf2-related kinase 1).

TSSK3_HUMAN
θ value	2.13179e-17 (rank : 254)	NC score	0.852180 (rank : 145)
Query Neighborhood Hits	1959	Target Neighborhood Hits	806	Shared Neighborhood Hits	789
SwissProt Accessions	Q96PN8	Gene names	TSSK3, SPOGA3, STK22C
Domain Architecture
Description	Testis-specific serine/threonine-protein kinase 3 (EC 2.7.11.1) (TSSK- 3) (Testis-specific kinase 3) (TSK-3) (Serine/threonine-protein kinase 22C).

TSSK3_MOUSE
θ value	2.13179e-17 (rank : 255)	NC score	0.851925 (rank : 146)
Query Neighborhood Hits	1959	Target Neighborhood Hits	806	Shared Neighborhood Hits	788
SwissProt Accessions	Q9D2E1, Q9JL98	Gene names	Tssk3, Stk22c, Stk22d
Domain Architecture
Description	Testis-specific serine/threonine-protein kinase 3 (EC 2.7.11.1) (TSSK- 3) (Testis-specific kinase 3) (TSK-3) (Serine/threonine-protein kinase 22C).

CHK1_MOUSE
θ value	2.7842e-17 (rank : 256)	NC score	0.860713 (rank : 82)
Query Neighborhood Hits	1959	Target Neighborhood Hits	839	Shared Neighborhood Hits	819
SwissProt Accessions	O35280, O54925, Q8CI40, Q9D0N2	Gene names	Chek1, Chk1
Domain Architecture
Description	Serine/threonine-protein kinase Chk1 (EC 2.7.11.1).

MRCKB_MOUSE
θ value	2.7842e-17 (rank : 257)	NC score	0.724636 (rank : 585)
Query Neighborhood Hits	1959	Target Neighborhood Hits	2180	Shared Neighborhood Hits	946
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

NCAM2_HUMAN
θ value	2.7842e-17 (rank : 258)	NC score	0.394046 (rank : 860)
Query Neighborhood Hits	1959	Target Neighborhood Hits	441	Shared Neighborhood Hits	327
SwissProt Accessions	O15394	Gene names	NCAM2, NCAM21
Domain Architecture
Description	Neural cell adhesion molecule 2 precursor (N-CAM 2).

RK_MOUSE
θ value	2.7842e-17 (rank : 259)	NC score	0.841819 (rank : 209)
Query Neighborhood Hits	1959	Target Neighborhood Hits	829	Shared Neighborhood Hits	812
SwissProt Accessions	Q9WVL4	Gene names	Grk1, Rhok
Domain Architecture
Description	Rhodopsin kinase precursor (EC 2.7.11.14) (RK) (G protein-coupled receptor kinase 1).

CDC2_HUMAN
θ value	3.63628e-17 (rank : 260)	NC score	0.826630 (rank : 309)
Query Neighborhood Hits	1959	Target Neighborhood Hits	842	Shared Neighborhood Hits	820
SwissProt Accessions	P06493, O60764	Gene names	CDC2
Domain Architecture
Description	Cell division control protein 2 homolog (EC 2.7.11.22) (EC 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1).

M3K12_HUMAN
θ value	3.63628e-17 (rank : 261)	NC score	0.788277 (rank : 478)
Query Neighborhood Hits	1959	Target Neighborhood Hits	940	Shared Neighborhood Hits	851
SwissProt Accessions	Q12852, Q86VQ5, Q8WY25	Gene names	MAP3K12, ZPK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

M3K12_MOUSE
θ value	3.63628e-17 (rank : 262)	NC score	0.788123 (rank : 479)
Query Neighborhood Hits	1959	Target Neighborhood Hits	957	Shared Neighborhood Hits	854
SwissProt Accessions	Q60700, P70286, Q3TLL7, Q8C4N7, Q8CBX3, Q8CDL6	Gene names	Map3k12, Zpk
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

M3K5_HUMAN
θ value	3.63628e-17 (rank : 263)	NC score	0.840278 (rank : 219)
Query Neighborhood Hits	1959	Target Neighborhood Hits	868	Shared Neighborhood Hits	819
SwissProt Accessions	Q99683, Q5THN3, Q99461	Gene names	MAP3K5, ASK1, MAPKKK5, MEKK5
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5) (Apoptosis signal- regulating kinase 1) (ASK-1).

M3K5_MOUSE
θ value	3.63628e-17 (rank : 264)	NC score	0.840384 (rank : 218)
Query Neighborhood Hits	1959	Target Neighborhood Hits	867	Shared Neighborhood Hits	820
SwissProt Accessions	O35099	Gene names	Map3k5, Ask1, Mekk5
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5) (Apoptosis signal- regulating kinase 1) (ASK-1).

PAK4_MOUSE
θ value	3.63628e-17 (rank : 265)	NC score	0.850676 (rank : 156)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1098	Shared Neighborhood Hits	934
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

PKN2_HUMAN
θ value	3.63628e-17 (rank : 266)	NC score	0.835042 (rank : 251)
Query Neighborhood Hits	1959	Target Neighborhood Hits	892	Shared Neighborhood Hits	819
SwissProt Accessions	Q16513, Q9H1W4	Gene names	PKN2, PRK2, PRKCL2
Domain Architecture
Description	Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein kinase C- like 2) (Protein-kinase C-related kinase 2).

PKN2_MOUSE
θ value	3.63628e-17 (rank : 267)	NC score	0.835323 (rank : 247)
Query Neighborhood Hits	1959	Target Neighborhood Hits	899	Shared Neighborhood Hits	820
SwissProt Accessions	Q8BWW9, Q80WS2, Q8BJL7	Gene names	Pkn2, Prkcl2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein kinase C- like 2) (Protein-kinase C-related kinase 2).

PTPRD_HUMAN
θ value	3.63628e-17 (rank : 268)	NC score	0.277612 (rank : 972)
Query Neighborhood Hits	1959	Target Neighborhood Hits	485	Shared Neighborhood Hits	314
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

CNTN2_MOUSE
θ value	4.74913e-17 (rank : 269)	NC score	0.387246 (rank : 877)
Query Neighborhood Hits	1959	Target Neighborhood Hits	450	Shared Neighborhood Hits	335
SwissProt Accessions	Q61330, Q6NZJ4, Q7TSJ5	Gene names	Cntn2, Tax
Domain Architecture	No domain graphic available
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

IKKB_MOUSE
θ value	4.74913e-17 (rank : 270)	NC score	0.840826 (rank : 215)
Query Neighborhood Hits	1959	Target Neighborhood Hits	984	Shared Neighborhood Hits	820
SwissProt Accessions	O88351, Q9R1J6	Gene names	Ikbkb, Ikkb
Domain Architecture
Description	Inhibitor of nuclear factor kappa B kinase subunit beta (EC 2.7.11.10) (I-kappa-B-kinase beta) (IkBKB) (IKK-beta) (IKK-B) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB).

MKNK2_MOUSE
θ value	4.74913e-17 (rank : 271)	NC score	0.855172 (rank : 122)
Query Neighborhood Hits	1959	Target Neighborhood Hits	819	Shared Neighborhood Hits	800
SwissProt Accessions	Q8CDB0, O08606, Q75PY0, Q9D893	Gene names	Mknk2, Mnk2
Domain Architecture
Description	MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 2) (Mnk2).

STK24_MOUSE
θ value	4.74913e-17 (rank : 272)	NC score	0.830565 (rank : 284)
Query Neighborhood Hits	1959	Target Neighborhood Hits	856	Shared Neighborhood Hits	827
SwissProt Accessions	Q99KH8	Gene names	Stk24
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 24 (EC 2.7.11.1).

KPCI_MOUSE
θ value	6.20254e-17 (rank : 273)	NC score	0.831792 (rank : 276)
Query Neighborhood Hits	1959	Target Neighborhood Hits	888	Shared Neighborhood Hits	825
SwissProt Accessions	Q62074	Gene names	Prkci, Pkcl
Domain Architecture
Description	Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota) (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota).

NRCAM_HUMAN
θ value	6.20254e-17 (rank : 274)	NC score	0.382618 (rank : 886)
Query Neighborhood Hits	1959	Target Neighborhood Hits	439	Shared Neighborhood Hits	329
SwissProt Accessions	Q92823, O15051, O15179, Q9UHI3, Q9UHI4	Gene names	NRCAM, KIAA0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (hBravo).

ROCK2_HUMAN
θ value	6.20254e-17 (rank : 275)	NC score	0.738120 (rank : 563)
Query Neighborhood Hits	1959	Target Neighborhood Hits	2073	Shared Neighborhood Hits	916
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

STK38_HUMAN
θ value	6.20254e-17 (rank : 276)	NC score	0.823618 (rank : 329)
Query Neighborhood Hits	1959	Target Neighborhood Hits	840	Shared Neighborhood Hits	796
SwissProt Accessions	Q15208	Gene names	STK38, NDR1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1 protein kinase) (Nuclear Dbf2-related kinase 1).

M3K15_HUMAN
θ value	8.10077e-17 (rank : 277)	NC score	0.839346 (rank : 224)
Query Neighborhood Hits	1959	Target Neighborhood Hits	914	Shared Neighborhood Hits	827
SwissProt Accessions	Q6ZN16, Q5JPR4, Q6ZMV3	Gene names	MAP3K15
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 15 (EC 2.7.11.25) (MAPK/ERK kinase kinase 15) (MEK kinase 15) (MEKK 15).

MAK_MOUSE
θ value	8.10077e-17 (rank : 278)	NC score	0.821334 (rank : 341)
Query Neighborhood Hits	1959	Target Neighborhood Hits	873	Shared Neighborhood Hits	830
SwissProt Accessions	Q04859	Gene names	Mak, Rck
Domain Architecture
Description	Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male germ cell- associated kinase) (Protein kinase RCK).

NIM1_MOUSE
θ value	8.10077e-17 (rank : 279)	NC score	0.858905 (rank : 96)
Query Neighborhood Hits	1959	Target Neighborhood Hits	850	Shared Neighborhood Hits	822
SwissProt Accessions	Q8BHI9, Q8BXQ9	Gene names	NIM1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase NIM1 (EC 2.7.11.1).

SDK1_MOUSE
θ value	8.10077e-17 (rank : 280)	NC score	0.380126 (rank : 888)
Query Neighborhood Hits	1959	Target Neighborhood Hits	495	Shared Neighborhood Hits	344
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

ST32B_HUMAN
θ value	8.10077e-17 (rank : 281)	NC score	0.844130 (rank : 198)
Query Neighborhood Hits	1959	Target Neighborhood Hits	830	Shared Neighborhood Hits	814
SwissProt Accessions	Q9NY57, Q6UXH3, Q8IY14	Gene names	STK32B
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 32B (EC 2.7.11.1) (YANK2).

M3K13_HUMAN
θ value	1.058e-16 (rank : 282)	NC score	0.795666 (rank : 462)
Query Neighborhood Hits	1959	Target Neighborhood Hits	911	Shared Neighborhood Hits	834
SwissProt Accessions	O43283	Gene names	MAP3K13, LZK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Mixed lineage kinase) (MLK) (Leucine zipper-bearing kinase).

M3K2_MOUSE
θ value	1.058e-16 (rank : 283)	NC score	0.846977 (rank : 171)
Query Neighborhood Hits	1959	Target Neighborhood Hits	846	Shared Neighborhood Hits	821
SwissProt Accessions	Q61083	Gene names	Map3k2, Mekk2
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2).

MKNK2_HUMAN
θ value	1.058e-16 (rank : 284)	NC score	0.855656 (rank : 120)
Query Neighborhood Hits	1959	Target Neighborhood Hits	821	Shared Neighborhood Hits	802
SwissProt Accessions	Q9HBH9, Q6GPI3, Q9HBH8, Q9UHR0, Q9Y2N6	Gene names	MKNK2, MNK2
Domain Architecture
Description	MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 2) (Mnk2).

MRCKA_HUMAN
θ value	1.058e-16 (rank : 285)	NC score	0.736201 (rank : 565)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1999	Shared Neighborhood Hits	901
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

MRCKB_HUMAN
θ value	1.058e-16 (rank : 286)	NC score	0.717134 (rank : 593)
Query Neighborhood Hits	1959	Target Neighborhood Hits	2239	Shared Neighborhood Hits	960
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

ROCK2_MOUSE
θ value	1.058e-16 (rank : 287)	NC score	0.731228 (rank : 573)
Query Neighborhood Hits	1959	Target Neighborhood Hits	2072	Shared Neighborhood Hits	911
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

TSSK6_MOUSE
θ value	1.058e-16 (rank : 288)	NC score	0.855084 (rank : 123)
Query Neighborhood Hits	1959	Target Neighborhood Hits	824	Shared Neighborhood Hits	810
SwissProt Accessions	Q925K9, Q5RL09, Q8C625	Gene names	Tssk6, Sstk
Domain Architecture	No domain graphic available
Description	Testis-specific serine/threonine-protein kinase 6 (EC 2.7.11.1) (TSSK- 6) (Small serine/threonine kinase) (Serine/threonine-protein kinase SSTK).

CDKL5_HUMAN
θ value	1.38178e-16 (rank : 289)	NC score	0.835261 (rank : 248)
Query Neighborhood Hits	1959	Target Neighborhood Hits	967	Shared Neighborhood Hits	867
SwissProt Accessions	O76039, Q14198, Q5H985, Q9UJL6	Gene names	CDKL5, STK9
Domain Architecture
Description	Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine- protein kinase 9).

MK03_MOUSE
θ value	1.38178e-16 (rank : 290)	NC score	0.805754 (rank : 421)
Query Neighborhood Hits	1959	Target Neighborhood Hits	840	Shared Neighborhood Hits	817
SwissProt Accessions	Q63844, Q61531, Q8K0X5, Q91YW5	Gene names	Mapk3, Erk1, Prkm3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 3 (EC 2.7.11.24) (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase 1) (MAPK 1) (p44-ERK1) (ERT2) (p44-MAPK) (Microtubule- associated protein 2 kinase) (MNK1).

NEK2_HUMAN
θ value	1.38178e-16 (rank : 291)	NC score	0.846962 (rank : 172)
Query Neighborhood Hits	1959	Target Neighborhood Hits	908	Shared Neighborhood Hits	808
SwissProt Accessions	P51955, Q53FD6, Q5VXZ1, Q6NZX8, Q7Z634, Q86XH2, Q96QN9	Gene names	NEK2, NLK1
Domain Architecture
Description	Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (NimA-related protein kinase 2) (NimA-like protein kinase 1) (HSPK 21).

SLK_MOUSE
θ value	1.38178e-16 (rank : 292)	NC score	0.807089 (rank : 411)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1798	Shared Neighborhood Hits	923
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

TTK_HUMAN
θ value	1.38178e-16 (rank : 293)	NC score	0.838449 (rank : 228)
Query Neighborhood Hits	1959	Target Neighborhood Hits	816	Shared Neighborhood Hits	775
SwissProt Accessions	P33981	Gene names	TTK, MPS1L1
Domain Architecture
Description	Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein kinase) (PYT).

CNTN2_HUMAN
θ value	1.80466e-16 (rank : 294)	NC score	0.387822 (rank : 875)
Query Neighborhood Hits	1959	Target Neighborhood Hits	440	Shared Neighborhood Hits	331
SwissProt Accessions	Q02246, P78432	Gene names	CNTN2, TAG1, TAX1
Domain Architecture
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

GRK4_MOUSE
θ value	1.80466e-16 (rank : 295)	NC score	0.828653 (rank : 294)
Query Neighborhood Hits	1959	Target Neighborhood Hits	808	Shared Neighborhood Hits	797
SwissProt Accessions	O70291	Gene names	Grk4, Gprk2l
Domain Architecture
Description	G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK4).

GRK5_HUMAN
θ value	1.80466e-16 (rank : 296)	NC score	0.834594 (rank : 259)
Query Neighborhood Hits	1959	Target Neighborhood Hits	819	Shared Neighborhood Hits	802
SwissProt Accessions	P34947	Gene names	GRK5, GPRK5
Domain Architecture
Description	G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK5).

GRK5_MOUSE
θ value	1.80466e-16 (rank : 297)	NC score	0.834911 (rank : 254)
Query Neighborhood Hits	1959	Target Neighborhood Hits	823	Shared Neighborhood Hits	802
SwissProt Accessions	Q8VEB1, O70292, O70297	Gene names	Grk5, Gprk5
Domain Architecture
Description	G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK5).

KPCA_MOUSE
θ value	1.80466e-16 (rank : 298)	NC score	0.812091 (rank : 385)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1067	Shared Neighborhood Hits	817
SwissProt Accessions	P20444	Gene names	Prkca, Pkca
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

PASK_MOUSE
θ value	1.80466e-16 (rank : 299)	NC score	0.858311 (rank : 99)
Query Neighborhood Hits	1959	Target Neighborhood Hits	867	Shared Neighborhood Hits	817
SwissProt Accessions	Q8CEE6, Q91YD8	Gene names	Pask, Kiaa0135
Domain Architecture
Description	PAS domain-containing serine/threonine-protein kinase (EC 2.7.11.1) (PAS-kinase) (PASKIN).

SGK1_HUMAN
θ value	1.80466e-16 (rank : 300)	NC score	0.844155 (rank : 196)
Query Neighborhood Hits	1959	Target Neighborhood Hits	848	Shared Neighborhood Hits	823
SwissProt Accessions	O00141, Q5TCN3, Q9UN56	Gene names	SGK, SGK1
Domain Architecture
Description	Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 1).

MAK_HUMAN
θ value	2.35696e-16 (rank : 301)	NC score	0.819832 (rank : 348)
Query Neighborhood Hits	1959	Target Neighborhood Hits	857	Shared Neighborhood Hits	822
SwissProt Accessions	P20794, Q9NUH7	Gene names	MAK
Domain Architecture
Description	Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male germ cell- associated kinase).

MRCKG_MOUSE
θ value	2.35696e-16 (rank : 302)	NC score	0.784679 (rank : 492)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1466	Shared Neighborhood Hits	862
SwissProt Accessions	Q80UW5	Gene names	Cdc42bpg
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

TNIK_HUMAN
θ value	2.35696e-16 (rank : 303)	NC score	0.806066 (rank : 416)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1570	Shared Neighborhood Hits	940
SwissProt Accessions	Q9UKE5, O60298, Q8WUY7, Q9UKD8, Q9UKD9, Q9UKE0, Q9UKE1, Q9UKE2, Q9UKE3, Q9UKE4	Gene names	TNIK, KIAA0551
Domain Architecture
Description	TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1).

CDKL2_MOUSE
θ value	3.07829e-16 (rank : 304)	NC score	0.831007 (rank : 281)
Query Neighborhood Hits	1959	Target Neighborhood Hits	854	Shared Neighborhood Hits	820
SwissProt Accessions	Q9QUK0, Q3UL60, Q3V3X7, Q9QYI1, Q9QYI2	Gene names	Cdkl2, Kkiamre, Kkm
Domain Architecture	No domain graphic available
Description	Cyclin-dependent kinase-like 2 (EC 2.7.11.22) (Serine/threonine- protein kinase KKIAMRE).

IKKB_HUMAN
θ value	3.07829e-16 (rank : 305)	NC score	0.841226 (rank : 214)
Query Neighborhood Hits	1959	Target Neighborhood Hits	980	Shared Neighborhood Hits	826
SwissProt Accessions	O14920, O75327	Gene names	IKBKB, IKKB
Domain Architecture
Description	Inhibitor of nuclear factor kappa B kinase subunit beta (EC 2.7.11.10) (I-kappa-B-kinase beta) (IkBKB) (IKK-beta) (IKK-B) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB).

KPCL_MOUSE
θ value	3.07829e-16 (rank : 306)	NC score	0.828725 (rank : 292)
Query Neighborhood Hits	1959	Target Neighborhood Hits	891	Shared Neighborhood Hits	809
SwissProt Accessions	P23298	Gene names	Prkch, Pkch
Domain Architecture
Description	Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta) (PKC-L).

PFTK1_HUMAN
θ value	3.07829e-16 (rank : 307)	NC score	0.819522 (rank : 351)
Query Neighborhood Hits	1959	Target Neighborhood Hits	834	Shared Neighborhood Hits	808
SwissProt Accessions	O94921, Q75N06, Q75N22, Q8N764, Q9H3D7, Q9UDR0	Gene names	PFTK1, KIAA0834
Domain Architecture
Description	Serine/threonine-protein kinase PFTAIRE-1 (EC 2.7.11.22).

SGK1_MOUSE
θ value	3.07829e-16 (rank : 308)	NC score	0.843988 (rank : 200)
Query Neighborhood Hits	1959	Target Neighborhood Hits	848	Shared Neighborhood Hits	822
SwissProt Accessions	Q9WVC6	Gene names	Sgk, Sgk1
Domain Architecture
Description	Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 1).

ULK1_MOUSE
θ value	3.07829e-16 (rank : 309)	NC score	0.857725 (rank : 105)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1214	Shared Neighborhood Hits	989
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

CDC2_MOUSE
θ value	4.02038e-16 (rank : 310)	NC score	0.825687 (rank : 318)
Query Neighborhood Hits	1959	Target Neighborhood Hits	838	Shared Neighborhood Hits	819
SwissProt Accessions	P11440, P70337, Q3TI12	Gene names	Cdc2, Cdc2a
Domain Architecture
Description	Cell division control protein 2 homolog (EC 2.7.11.22) (EC 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1).

M3K2_HUMAN
θ value	4.02038e-16 (rank : 311)	NC score	0.845479 (rank : 187)
Query Neighborhood Hits	1959	Target Neighborhood Hits	849	Shared Neighborhood Hits	825
SwissProt Accessions	Q9Y2U5, Q53QL9, Q53S75, Q59GZ6, Q8NC32, Q9NYK3	Gene names	MAP3K2, MAPKKK2, MEKK2
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2).

NEK11_MOUSE
θ value	4.02038e-16 (rank : 312)	NC score	0.841243 (rank : 212)
Query Neighborhood Hits	1959	Target Neighborhood Hits	875	Shared Neighborhood Hits	822
SwissProt Accessions	Q8C0Q4, Q8BLS6, Q8BW62	Gene names	Nek11
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11).

NEK1_MOUSE
θ value	4.02038e-16 (rank : 313)	NC score	0.844151 (rank : 197)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1311	Shared Neighborhood Hits	901
SwissProt Accessions	P51954	Gene names	Nek1
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1).

SDK2_MOUSE
θ value	4.02038e-16 (rank : 314)	NC score	0.377391 (rank : 890)
Query Neighborhood Hits	1959	Target Neighborhood Hits	480	Shared Neighborhood Hits	346
SwissProt Accessions	Q6V4S5, Q3TTK1, Q5U5W7, Q6ZPP2	Gene names	Sdk2, Kiaa1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

TTK_MOUSE
θ value	4.02038e-16 (rank : 315)	NC score	0.837170 (rank : 237)
Query Neighborhood Hits	1959	Target Neighborhood Hits	803	Shared Neighborhood Hits	758
SwissProt Accessions	P35761	Gene names	Ttk, Esk
Domain Architecture
Description	Dual specificity protein kinase TTK (EC 2.7.12.1) (ESK) (PYT).

LRIG2_MOUSE
θ value	5.25075e-16 (rank : 316)	NC score	0.280189 (rank : 967)
Query Neighborhood Hits	1959	Target Neighborhood Hits	586	Shared Neighborhood Hits	292
SwissProt Accessions	Q52KR2, Q69ZY8	Gene names	Lrig2, Kiaa0806
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor.

MK03_HUMAN
θ value	5.25075e-16 (rank : 317)	NC score	0.805641 (rank : 422)
Query Neighborhood Hits	1959	Target Neighborhood Hits	837	Shared Neighborhood Hits	817
SwissProt Accessions	P27361	Gene names	MAPK3, ERK1, PRKM3
Domain Architecture
Description	Mitogen-activated protein kinase 3 (EC 2.7.11.24) (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase 1) (MAPK 1) (p44-ERK1) (ERT2) (p44-MAPK) (Microtubule- associated protein 2 kinase).

NEK2_MOUSE
θ value	5.25075e-16 (rank : 318)	NC score	0.846937 (rank : 173)
Query Neighborhood Hits	1959	Target Neighborhood Hits	876	Shared Neighborhood Hits	806
SwissProt Accessions	O35942, O35959	Gene names	Nek2
Domain Architecture
Description	Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (NimA-related protein kinase 2).

PTPRF_HUMAN
θ value	5.25075e-16 (rank : 319)	NC score	0.282838 (rank : 963)
Query Neighborhood Hits	1959	Target Neighborhood Hits	489	Shared Neighborhood Hits	322
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

RK_HUMAN
θ value	5.25075e-16 (rank : 320)	NC score	0.838829 (rank : 227)
Query Neighborhood Hits	1959	Target Neighborhood Hits	835	Shared Neighborhood Hits	814
SwissProt Accessions	Q15835	Gene names	GRK1, RHOK
Domain Architecture
Description	Rhodopsin kinase precursor (EC 2.7.11.14) (RK) (G protein-coupled receptor kinase 1).

TSSK6_HUMAN
θ value	5.25075e-16 (rank : 321)	NC score	0.854083 (rank : 130)
Query Neighborhood Hits	1959	Target Neighborhood Hits	824	Shared Neighborhood Hits	811
SwissProt Accessions	Q9BXA6, Q6ZMC4, Q96LJ4	Gene names	TSSK6, FKSG82, SSTK
Domain Architecture	No domain graphic available
Description	Testis-specific serine/threonine-protein kinase 6 (EC 2.7.11.1) (TSSK- 6) (Small serine/threonine kinase) (Serine/threonine-protein kinase SSTK).

MAST2_HUMAN
θ value	6.85773e-16 (rank : 322)	NC score	0.830173 (rank : 287)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1189	Shared Neighborhood Hits	931
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MAST2_MOUSE
θ value	6.85773e-16 (rank : 323)	NC score	0.831139 (rank : 280)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1110	Shared Neighborhood Hits	899
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

NEK4_MOUSE
θ value	6.85773e-16 (rank : 324)	NC score	0.846255 (rank : 184)
Query Neighborhood Hits	1959	Target Neighborhood Hits	899	Shared Neighborhood Hits	836
SwissProt Accessions	Q9Z1J2, O35673, Q9R1J1	Gene names	Nek4, Stk2
Domain Architecture
Description	Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2).

PFTK1_MOUSE
θ value	6.85773e-16 (rank : 325)	NC score	0.819559 (rank : 350)
Query Neighborhood Hits	1959	Target Neighborhood Hits	835	Shared Neighborhood Hits	808
SwissProt Accessions	O35495, O35848	Gene names	Pftk1
Domain Architecture
Description	Serine/threonine-protein kinase PFTAIRE-1 (EC 2.7.11.22).

PKN3_HUMAN
θ value	6.85773e-16 (rank : 326)	NC score	0.834491 (rank : 261)
Query Neighborhood Hits	1959	Target Neighborhood Hits	893	Shared Neighborhood Hits	831
SwissProt Accessions	Q6P5Z2, Q9UM03	Gene names	PKN3, PKNBETA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

PTPRD_MOUSE
θ value	6.85773e-16 (rank : 327)	NC score	0.283059 (rank : 961)
Query Neighborhood Hits	1959	Target Neighborhood Hits	491	Shared Neighborhood Hits	320
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

CDK2_MOUSE
θ value	8.95645e-16 (rank : 328)	NC score	0.818635 (rank : 354)
Query Neighborhood Hits	1959	Target Neighborhood Hits	828	Shared Neighborhood Hits	812
SwissProt Accessions	P97377, O55105	Gene names	Cdk2
Domain Architecture
Description	Cell division protein kinase 2 (EC 2.7.11.22).

CDK3_HUMAN
θ value	8.95645e-16 (rank : 329)	NC score	0.822810 (rank : 336)
Query Neighborhood Hits	1959	Target Neighborhood Hits	843	Shared Neighborhood Hits	820
SwissProt Accessions	Q00526	Gene names	CDK3
Domain Architecture
Description	Cell division protein kinase 3 (EC 2.7.11.22).

GRK6_HUMAN
θ value	8.95645e-16 (rank : 330)	NC score	0.834598 (rank : 258)
Query Neighborhood Hits	1959	Target Neighborhood Hits	823	Shared Neighborhood Hits	808
SwissProt Accessions	P43250, O60541, Q13652	Gene names	GRK6, GPRK6
Domain Architecture
Description	G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK6).

KPCI_HUMAN
θ value	8.95645e-16 (rank : 331)	NC score	0.831373 (rank : 277)
Query Neighborhood Hits	1959	Target Neighborhood Hits	885	Shared Neighborhood Hits	826
SwissProt Accessions	P41743, Q8WW06	Gene names	PRKCI, DXS1179E
Domain Architecture
Description	Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota) (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) (PRKC-lambda/iota).

NEK4_HUMAN
θ value	8.95645e-16 (rank : 332)	NC score	0.844855 (rank : 192)
Query Neighborhood Hits	1959	Target Neighborhood Hits	883	Shared Neighborhood Hits	828
SwissProt Accessions	P51957	Gene names	NEK4, STK2
Domain Architecture
Description	Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2) (Serine/threonine-protein kinase NRK2).

SLK_HUMAN
θ value	8.95645e-16 (rank : 333)	NC score	0.805256 (rank : 426)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1775	Shared Neighborhood Hits	920
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

ST32B_MOUSE
θ value	8.95645e-16 (rank : 334)	NC score	0.844552 (rank : 195)
Query Neighborhood Hits	1959	Target Neighborhood Hits	828	Shared Neighborhood Hits	813
SwissProt Accessions	Q9JJX8, Q7TMD3, Q8C4E0	Gene names	Stk32b, Stk32
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 32B (EC 2.7.11.1).

NLK_HUMAN
θ value	1.16975e-15 (rank : 335)	NC score	0.808482 (rank : 406)
Query Neighborhood Hits	1959	Target Neighborhood Hits	840	Shared Neighborhood Hits	822
SwissProt Accessions	Q9UBE8, Q2PNI9, Q6P2A3	Gene names	NLK, LAK1
Domain Architecture	No domain graphic available
Description	Serine/threonine kinase NLK (EC 2.7.11.24) (Nemo-like kinase) (Protein LAK1).

NLK_MOUSE
θ value	1.16975e-15 (rank : 336)	NC score	0.808533 (rank : 405)
Query Neighborhood Hits	1959	Target Neighborhood Hits	839	Shared Neighborhood Hits	822
SwissProt Accessions	O54949, Q6PF98	Gene names	Nlk
Domain Architecture	No domain graphic available
Description	Serine/threonine kinase NLK (EC 2.7.11.24) (Nemo-like kinase).

TSSK4_MOUSE
θ value	1.16975e-15 (rank : 337)	NC score	0.854840 (rank : 125)
Query Neighborhood Hits	1959	Target Neighborhood Hits	840	Shared Neighborhood Hits	822
SwissProt Accessions	Q9D411	Gene names	Tssk4
Domain Architecture	No domain graphic available
Description	Testis-specific serine/threonine-protein kinase 4 (EC 2.7.11.1) (TSSK- 4) (Testis-specific kinase 4) (TSK-4).

MAST4_HUMAN
θ value	1.52774e-15 (rank : 338)	NC score	0.830275 (rank : 286)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1804	Shared Neighborhood Hits	1149
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

TAOK1_HUMAN
θ value	1.52774e-15 (rank : 339)	NC score	0.775268 (rank : 511)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1734	Shared Neighborhood Hits	916
SwissProt Accessions	Q7L7X3, Q96L75, Q9H2K7, Q9H7S5, Q9P2I6	Gene names	TAOK1, KIAA1361, MAP3K16
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1) (STE20-like kinase PSK2) (Kinase from chicken homolog B) (hKFC-B).

TAOK1_MOUSE
θ value	1.52774e-15 (rank : 340)	NC score	0.775731 (rank : 510)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1720	Shared Neighborhood Hits	913
SwissProt Accessions	Q5F2E8, Q69ZL2, Q8JZX2, Q91VG7	Gene names	Taok1, Kiaa1361
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1).

CDK5_MOUSE
θ value	1.99529e-15 (rank : 341)	NC score	0.816152 (rank : 363)
Query Neighborhood Hits	1959	Target Neighborhood Hits	826	Shared Neighborhood Hits	810
SwissProt Accessions	P49615	Gene names	Cdk5, Crk6
Domain Architecture
Description	Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) (CRK6).

CDKL2_HUMAN
θ value	1.99529e-15 (rank : 342)	NC score	0.830451 (rank : 285)
Query Neighborhood Hits	1959	Target Neighborhood Hits	838	Shared Neighborhood Hits	815
SwissProt Accessions	Q92772	Gene names	CDKL2
Domain Architecture	No domain graphic available
Description	Cyclin-dependent kinase-like 2 (EC 2.7.11.22) (Serine/threonine- protein kinase KKIAMRE) (Protein kinase p56 KKIAMRE).

GRK6_MOUSE
θ value	1.99529e-15 (rank : 343)	NC score	0.833777 (rank : 265)
Query Neighborhood Hits	1959	Target Neighborhood Hits	820	Shared Neighborhood Hits	807
SwissProt Accessions	O70293, O70294, O70295	Gene names	Grk6, Gprk6
Domain Architecture
Description	G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK6).

KPCZ_HUMAN
θ value	1.99529e-15 (rank : 344)	NC score	0.826957 (rank : 306)
Query Neighborhood Hits	1959	Target Neighborhood Hits	884	Shared Neighborhood Hits	818
SwissProt Accessions	Q05513, Q15207, Q5SYT5, Q969S4	Gene names	PRKCZ, PKC2
Domain Architecture
Description	Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta).

KPCZ_MOUSE
θ value	1.99529e-15 (rank : 345)	NC score	0.826998 (rank : 304)
Query Neighborhood Hits	1959	Target Neighborhood Hits	882	Shared Neighborhood Hits	818
SwissProt Accessions	Q02956	Gene names	Prkcz, Pkcz
Domain Architecture
Description	Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta).

LRIG1_MOUSE
θ value	1.99529e-15 (rank : 346)	NC score	0.278108 (rank : 971)
Query Neighborhood Hits	1959	Target Neighborhood Hits	627	Shared Neighborhood Hits	297
SwissProt Accessions	P70193	Gene names	Lrig1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

M4K1_HUMAN
θ value	1.99529e-15 (rank : 347)	NC score	0.825876 (rank : 316)
Query Neighborhood Hits	1959	Target Neighborhood Hits	884	Shared Neighborhood Hits	829
SwissProt Accessions	Q92918	Gene names	MAP4K1, HPK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1) (Hematopoietic progenitor kinase).

MYO3B_HUMAN
θ value	1.99529e-15 (rank : 348)	NC score	0.717747 (rank : 592)
Query Neighborhood Hits	1959	Target Neighborhood Hits	923	Shared Neighborhood Hits	838
SwissProt Accessions	Q8WXR4, Q8IX64, Q8IX65, Q8IX66, Q8IX67, Q8IX68	Gene names	MYO3B
Domain Architecture
Description	Myosin IIIB (EC 2.7.11.1).

TAOK2_MOUSE
θ value	1.99529e-15 (rank : 349)	NC score	0.797158 (rank : 457)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1373	Shared Neighborhood Hits	876
SwissProt Accessions	Q6ZQ29, Q7TSS8	Gene names	Taok2, Kiaa0881
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Thousand and one amino acid protein 2).

VGFR1_HUMAN
θ value	1.99529e-15 (rank : 350)	NC score	0.720242 (rank : 590)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1109	Shared Neighborhood Hits	1017
SwissProt Accessions	P17948, O60722, P16057, Q12954	Gene names	FLT1, FLT, FRT
Domain Architecture
Description	Vascular endothelial growth factor receptor 1 precursor (EC 2.7.10.1) (VEGFR-1) (Vascular permeability factor receptor) (Tyrosine-protein kinase receptor FLT) (Flt-1) (Tyrosine-protein kinase FRT) (Fms-like tyrosine kinase 1).

CDK5_HUMAN
θ value	2.60593e-15 (rank : 351)	NC score	0.816289 (rank : 361)
Query Neighborhood Hits	1959	Target Neighborhood Hits	826	Shared Neighborhood Hits	810
SwissProt Accessions	Q00535	Gene names	CDK5
Domain Architecture
Description	Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE).

DMPK_MOUSE
θ value	2.60593e-15 (rank : 352)	NC score	0.818419 (rank : 356)
Query Neighborhood Hits	1959	Target Neighborhood Hits	908	Shared Neighborhood Hits	811
SwissProt Accessions	P54265	Gene names	Dmpk, Dm15, Mdpk
Domain Architecture
Description	Myotonin-protein kinase (EC 2.7.11.1) (Myotonic dystrophy protein kinase) (MDPK) (DM-kinase) (DMK) (DMPK) (MT-PK).

IKKE_HUMAN
θ value	2.60593e-15 (rank : 353)	NC score	0.841767 (rank : 210)
Query Neighborhood Hits	1959	Target Neighborhood Hits	837	Shared Neighborhood Hits	798
SwissProt Accessions	Q14164	Gene names	IKBKE, IKKE, IKKI, KIAA0151
Domain Architecture
Description	Inhibitor of nuclear factor kappa-B kinase epsilon subunit (EC 2.7.11.10) (I kappa-B kinase epsilon) (IkBKE) (IKK-epsilon) (IKK- E) (Inducible I kappa-B kinase) (IKK-i).

MINK1_MOUSE
θ value	2.60593e-15 (rank : 354)	NC score	0.806494 (rank : 412)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1451	Shared Neighborhood Hits	916
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

STK10_MOUSE
θ value	2.60593e-15 (rank : 355)	NC score	0.768851 (rank : 524)
Query Neighborhood Hits	1959	Target Neighborhood Hits	2132	Shared Neighborhood Hits	981
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

VGFR1_MOUSE
θ value	2.60593e-15 (rank : 356)	NC score	0.725170 (rank : 584)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1118	Shared Neighborhood Hits	1016
SwissProt Accessions	P35969, O55094, Q61517	Gene names	Flt1, Emrk2, Flt
Domain Architecture
Description	Vascular endothelial growth factor receptor 1 precursor (EC 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) (Embryonic receptor kinase 2).

VGFR2_HUMAN
θ value	2.60593e-15 (rank : 357)	NC score	0.710842 (rank : 603)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1103	Shared Neighborhood Hits	1005
SwissProt Accessions	P35968, O60723, Q14178	Gene names	KDR, FLK1
Domain Architecture
Description	Vascular endothelial growth factor receptor 2 precursor (EC 2.7.10.1) (VEGFR-2) (Kinase insert domain receptor) (Protein-tyrosine kinase receptor Flk-1) (CD309 antigen).

ARBK1_HUMAN
θ value	3.40345e-15 (rank : 358)	NC score	0.824392 (rank : 324)
Query Neighborhood Hits	1959	Target Neighborhood Hits	859	Shared Neighborhood Hits	813
SwissProt Accessions	P25098, Q13837	Gene names	ADRBK1, BARK, BARK1, GRK2
Domain Architecture
Description	Beta-adrenergic receptor kinase 1 (EC 2.7.11.15) (Beta-ARK-1) (G- protein coupled receptor kinase 2).

LRIG2_HUMAN
θ value	3.40345e-15 (rank : 359)	NC score	0.281429 (rank : 965)
Query Neighborhood Hits	1959	Target Neighborhood Hits	595	Shared Neighborhood Hits	296
SwissProt Accessions	O94898, Q9NSN2	Gene names	LRIG2, KIAA0806, LIG2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor (LIG-2).

TSSK2_HUMAN
θ value	3.40345e-15 (rank : 360)	NC score	0.853027 (rank : 137)
Query Neighborhood Hits	1959	Target Neighborhood Hits	826	Shared Neighborhood Hits	808
SwissProt Accessions	Q96PF2, Q8IY55	Gene names	TSSK2, DGSG, SPOGA2, STK22B
Domain Architecture
Description	Testis-specific serine/threonine-protein kinase 2 (EC 2.7.11.1) (TSSK- 2) (Testis-specific kinase 2) (TSK-2) (Serine/threonine-protein kinase 22B) (DiGeorge syndrome protein G).

ULK4_MOUSE
θ value	3.40345e-15 (rank : 361)	NC score	0.847643 (rank : 169)
Query Neighborhood Hits	1959	Target Neighborhood Hits	793	Shared Neighborhood Hits	766
SwissProt Accessions	Q3V129, Q2VP87, Q32LZ6, Q8BLS0, Q8C8Z5, Q9D4H6	Gene names	Ulk4
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK4 (EC 2.7.11.1) (Unc-51-like kinase 4).

CDK7_HUMAN
θ value	4.44505e-15 (rank : 362)	NC score	0.819809 (rank : 349)
Query Neighborhood Hits	1959	Target Neighborhood Hits	833	Shared Neighborhood Hits	811
SwissProt Accessions	P50613, Q9BS60, Q9UE19	Gene names	CDK7, MO15
Domain Architecture
Description	Cell division protein kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (CDK- activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 kDa protein kinase) (P39 Mo15) (STK1) (CAK1).

CDK7_MOUSE
θ value	4.44505e-15 (rank : 363)	NC score	0.819901 (rank : 347)
Query Neighborhood Hits	1959	Target Neighborhood Hits	835	Shared Neighborhood Hits	812
SwissProt Accessions	Q03147, Q99KK3	Gene names	Cdk7, Cdkn7, Crk4, Mo15, Mpk-7
Domain Architecture
Description	Cell division protein kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (CDK- activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 kDa protein kinase) (P39 Mo15) (Protein-tyrosine kinase MPK-7) (CR4 protein kinase) (CRK4).

CDKL3_HUMAN
θ value	4.44505e-15 (rank : 364)	NC score	0.837073 (rank : 239)
Query Neighborhood Hits	1959	Target Neighborhood Hits	853	Shared Neighborhood Hits	823
SwissProt Accessions	Q8IVW4, Q9P114	Gene names	CDKL3, NKIAMRE
Domain Architecture	No domain graphic available
Description	Cyclin-dependent kinase-like 3 (EC 2.7.11.22) (Serine/threonine protein kinase NKIAMRE).

IKKE_MOUSE
θ value	4.44505e-15 (rank : 365)	NC score	0.840481 (rank : 217)
Query Neighborhood Hits	1959	Target Neighborhood Hits	848	Shared Neighborhood Hits	801
SwissProt Accessions	Q9R0T8	Gene names	Ikbke, Ikke, Ikki
Domain Architecture
Description	Inhibitor of nuclear factor kappa-B kinase epsilon subunit (EC 2.7.11.10) (I kappa-B kinase epsilon) (IkBKE) (IKK-epsilon) (IKK- E) (Inducible I kappa-B kinase) (IKK-i).

MST4_HUMAN
θ value	4.44505e-15 (rank : 366)	NC score	0.830044 (rank : 290)
Query Neighborhood Hits	1959	Target Neighborhood Hits	852	Shared Neighborhood Hits	822
SwissProt Accessions	Q9P289, Q3ZB77, Q9BXC4	Gene names	MST4, MASK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MST4 (EC 2.7.11.1) (STE20-like kinase MST4) (MST-4) (Mammalian STE20-like protein kinase 4) (Serine/threonine-protein kinase MASK) (Mst3 and SOK1-related kinase).

MST4_MOUSE
θ value	4.44505e-15 (rank : 367)	NC score	0.830099 (rank : 289)
Query Neighborhood Hits	1959	Target Neighborhood Hits	860	Shared Neighborhood Hits	822
SwissProt Accessions	Q99JT2	Gene names	Mst4
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MST4 (EC 2.7.11.1) (STE20-like kinase MST4) (MST-4) (Mammalian STE20-like protein kinase 4).

MYPC2_MOUSE
θ value	4.44505e-15 (rank : 368)	NC score	0.352339 (rank : 909)
Query Neighborhood Hits	1959	Target Neighborhood Hits	297	Shared Neighborhood Hits	250
SwissProt Accessions	Q5XKE0, Q8C109, Q8K2V0	Gene names	Mybpc2
Domain Architecture	No domain graphic available
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

STK10_HUMAN
θ value	4.44505e-15 (rank : 369)	NC score	0.790156 (rank : 472)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1921	Shared Neighborhood Hits	974
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

MYOTI_MOUSE
θ value	5.8054e-15 (rank : 370)	NC score	0.399315 (rank : 850)
Query Neighborhood Hits	1959	Target Neighborhood Hits	297	Shared Neighborhood Hits	258
SwissProt Accessions	Q9JIF9	Gene names	Myot, Ttid
Domain Architecture	No domain graphic available
Description	Myotilin (Titin immunoglobulin domain protein) (Myofibrillar titin- like Ig domains protein).

NEK8_HUMAN
θ value	5.8054e-15 (rank : 371)	NC score	0.837072 (rank : 240)
Query Neighborhood Hits	1959	Target Neighborhood Hits	872	Shared Neighborhood Hits	825
SwissProt Accessions	Q86SG6, Q2M1S6, Q8NDH1	Gene names	NEK8, JCK, NEK12A
Domain Architecture
Description	Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never in mitosis A-related kinase 8) (NimA-related protein kinase 8) (NIMA-related kinase 12a).

NEK8_MOUSE
θ value	5.8054e-15 (rank : 372)	NC score	0.837093 (rank : 238)
Query Neighborhood Hits	1959	Target Neighborhood Hits	872	Shared Neighborhood Hits	824
SwissProt Accessions	Q91ZR4, Q3U498, Q9D685	Gene names	Nek8, Jck
Domain Architecture
Description	Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never in mitosis A-related kinase 8) (NimA-related protein kinase 8).

TAOK2_HUMAN
θ value	5.8054e-15 (rank : 373)	NC score	0.809454 (rank : 401)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1172	Shared Neighborhood Hits	864
SwissProt Accessions	Q9UL54, O94957, Q6UW73, Q7LC09, Q9NSW2	Gene names	TAOK2, KIAA0881, MAP3K17, PSK, PSK1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Thousand and one amino acid protein 2) (Prostate-derived STE20-like kinase 1) (PSK-1) (Kinase from chicken homolog C) (hKFC-C).

M4K3_HUMAN
θ value	7.58209e-15 (rank : 374)	NC score	0.826349 (rank : 312)
Query Neighborhood Hits	1959	Target Neighborhood Hits	857	Shared Neighborhood Hits	822
SwissProt Accessions	Q8IVH8, Q8IVH7, Q9UDM5, Q9Y6R5	Gene names	MAP4K3
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3) (Germinal center kinase-related protein kinase) (GLK).

M4K4_HUMAN
θ value	7.58209e-15 (rank : 375)	NC score	0.793964 (rank : 465)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1589	Shared Neighborhood Hits	905
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

MINK1_HUMAN
θ value	7.58209e-15 (rank : 376)	NC score	0.806464 (rank : 413)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1477	Shared Neighborhood Hits	933
SwissProt Accessions	Q8N4C8, Q9P1X1, Q9P2R8	Gene names	MINK1, MAP4K6, MINK
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

SDK2_HUMAN
θ value	7.58209e-15 (rank : 377)	NC score	0.378280 (rank : 889)
Query Neighborhood Hits	1959	Target Neighborhood Hits	495	Shared Neighborhood Hits	345
SwissProt Accessions	Q58EX2, Q86VY3, Q9NTD2, Q9NVB3, Q9P214	Gene names	SDK2, KIAA1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

AL2S7_HUMAN
θ value	9.90251e-15 (rank : 378)	NC score	0.810367 (rank : 396)
Query Neighborhood Hits	1959	Target Neighborhood Hits	831	Shared Neighborhood Hits	809
SwissProt Accessions	Q96Q40, Q4ZG86, Q53TV1	Gene names	ALS2CR7
Domain Architecture
Description	Serine/threonine-protein kinase ALS2CR7 (EC 2.7.11.22) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein).

ARBK1_MOUSE
θ value	9.90251e-15 (rank : 379)	NC score	0.823607 (rank : 330)
Query Neighborhood Hits	1959	Target Neighborhood Hits	849	Shared Neighborhood Hits	812
SwissProt Accessions	Q99MK8, Q99LL8	Gene names	Adrbk1, Grk2
Domain Architecture
Description	Beta-adrenergic receptor kinase 1 (EC 2.7.11.15) (Beta-ARK-1) (G- protein-coupled receptor kinase 2).

CD2L7_HUMAN
θ value	9.90251e-15 (rank : 380)	NC score	0.815611 (rank : 365)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1275	Shared Neighborhood Hits	996
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

CDKL3_MOUSE
θ value	9.90251e-15 (rank : 381)	NC score	0.837787 (rank : 233)
Query Neighborhood Hits	1959	Target Neighborhood Hits	857	Shared Neighborhood Hits	824
SwissProt Accessions	Q8BLF2, Q5M6W2, Q8BKR2, Q8BL49, Q8BVE0, Q8K134	Gene names	Cdkl3
Domain Architecture	No domain graphic available
Description	Cyclin-dependent kinase-like 3 (EC 2.7.11.22).

FGRL1_HUMAN
θ value	9.90251e-15 (rank : 382)	NC score	0.391143 (rank : 864)
Query Neighborhood Hits	1959	Target Neighborhood Hits	335	Shared Neighborhood Hits	272
SwissProt Accessions	Q8N441, Q6PJN1, Q9BXN7, Q9H4D7	Gene names	FGFRL1, FGFR5, FHFR
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5) (FGFR-like protein) (FGF homologous factor receptor).

KPCE_HUMAN
θ value	9.90251e-15 (rank : 383)	NC score	0.826435 (rank : 311)
Query Neighborhood Hits	1959	Target Neighborhood Hits	906	Shared Neighborhood Hits	818
SwissProt Accessions	Q02156, Q53SL4, Q53SM5, Q9UE81	Gene names	PRKCE, PKCE
Domain Architecture
Description	Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon).

MAST1_HUMAN
θ value	9.90251e-15 (rank : 384)	NC score	0.827636 (rank : 301)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1146	Shared Neighborhood Hits	918
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MAST1_MOUSE
θ value	9.90251e-15 (rank : 385)	NC score	0.827315 (rank : 302)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1123	Shared Neighborhood Hits	906
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MYOTI_HUMAN
θ value	9.90251e-15 (rank : 386)	NC score	0.400311 (rank : 848)
Query Neighborhood Hits	1959	Target Neighborhood Hits	292	Shared Neighborhood Hits	257
SwissProt Accessions	Q9UBF9	Gene names	MYOT, TTID
Domain Architecture	No domain graphic available
Description	Myotilin (Titin immunoglobulin domain protein) (Myofibrillar titin- like Ig domains protein) (57 kDa cytoskeletal protein).

NEK11_HUMAN
θ value	9.90251e-15 (rank : 387)	NC score	0.837792 (rank : 232)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1043	Shared Neighborhood Hits	837
SwissProt Accessions	Q8NG66, Q5JPC0, Q8NG65, Q8TBY1, Q9H5F4	Gene names	NEK11
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11).

ARBK2_HUMAN
θ value	1.29331e-14 (rank : 388)	NC score	0.823913 (rank : 328)
Query Neighborhood Hits	1959	Target Neighborhood Hits	849	Shared Neighborhood Hits	810
SwissProt Accessions	P35626, Q9UGW9	Gene names	ADRBK2, BARK2, GRK3
Domain Architecture
Description	Beta-adrenergic receptor kinase 2 (EC 2.7.11.15) (Beta-ARK-2) (G- protein-coupled receptor kinase 3).

FGRL1_MOUSE
θ value	1.29331e-14 (rank : 389)	NC score	0.390220 (rank : 866)
Query Neighborhood Hits	1959	Target Neighborhood Hits	325	Shared Neighborhood Hits	275
SwissProt Accessions	Q91V87, Q920C2, Q920C3	Gene names	Fgfrl1, Fgfr5
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5).

ICK_HUMAN
θ value	1.29331e-14 (rank : 390)	NC score	0.821249 (rank : 343)
Query Neighborhood Hits	1959	Target Neighborhood Hits	867	Shared Neighborhood Hits	829
SwissProt Accessions	Q9UPZ9, O75985, Q5THL2, Q8IYH8, Q9BX17, Q9NYX3	Gene names	ICK, KIAA0936
Domain Architecture
Description	Serine/threonine-protein kinase ICK (EC 2.7.11.22) (Intestinal cell kinase) (hICK) (MAK-related kinase) (MRK) (Laryngeal cancer kinase 2) (LCK2).

LRIG3_HUMAN
θ value	1.29331e-14 (rank : 391)	NC score	0.266406 (rank : 982)
Query Neighborhood Hits	1959	Target Neighborhood Hits	601	Shared Neighborhood Hits	295
SwissProt Accessions	Q6UXM1, Q6UXL7, Q8NC72	Gene names	LRIG3, LIG3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor (LIG-3).

LSAMP_HUMAN
θ value	1.29331e-14 (rank : 392)	NC score	0.370071 (rank : 893)
Query Neighborhood Hits	1959	Target Neighborhood Hits	347	Shared Neighborhood Hits	275
SwissProt Accessions	Q13449, Q8IV49	Gene names	LSAMP, LAMP
Domain Architecture
Description	Limbic system-associated membrane protein precursor (LSAMP).

LSAMP_MOUSE
θ value	1.29331e-14 (rank : 393)	NC score	0.369967 (rank : 894)
Query Neighborhood Hits	1959	Target Neighborhood Hits	344	Shared Neighborhood Hits	274
SwissProt Accessions	Q8BLK3	Gene names	Lsamp
Domain Architecture	No domain graphic available
Description	Limbic system-associated membrane protein precursor (LSAMP).

NCA11_HUMAN
θ value	1.29331e-14 (rank : 394)	NC score	0.388444 (rank : 872)
Query Neighborhood Hits	1959	Target Neighborhood Hits	443	Shared Neighborhood Hits	327
SwissProt Accessions	P13591, Q15829, Q16180	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 140 kDa isoform precursor (N-CAM 140) (NCAM-140) (CD56 antigen).

TBK1_HUMAN
θ value	1.29331e-14 (rank : 395)	NC score	0.839429 (rank : 223)
Query Neighborhood Hits	1959	Target Neighborhood Hits	861	Shared Neighborhood Hits	791
SwissProt Accessions	Q9UHD2, Q8IYV3, Q9NUJ5	Gene names	TBK1, NAK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (TANK-binding kinase 1) (T2K) (NF-kappa-B-activating kinase).

ULK3_HUMAN
θ value	1.29331e-14 (rank : 396)	NC score	0.863598 (rank : 61)
Query Neighborhood Hits	1959	Target Neighborhood Hits	830	Shared Neighborhood Hits	816
SwissProt Accessions	Q6PHR2, Q9NPN5, Q9UFS4	Gene names	ULK3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3).

YSK4_HUMAN
θ value	1.29331e-14 (rank : 397)	NC score	0.835074 (rank : 250)
Query Neighborhood Hits	1959	Target Neighborhood Hits	921	Shared Neighborhood Hits	830
SwissProt Accessions	Q56UN5, Q56UN1, Q56UN2, Q56UN3, Q56UN4, Q8N4E9, Q9H5T2	Gene names	YSK4, RCK
Domain Architecture	No domain graphic available
Description	SPS1/STE20-related protein kinase YSK4 (EC 2.7.11.1) (Regulated in COPD, protein kinase).

GRK4_HUMAN
θ value	1.68911e-14 (rank : 398)	NC score	0.830785 (rank : 282)
Query Neighborhood Hits	1959	Target Neighborhood Hits	822	Shared Neighborhood Hits	803
SwissProt Accessions	P32298, O00641, O00642, Q13293, Q13294, Q13295, Q14453, Q14725, Q15313, Q15314, Q15315, Q15316	Gene names	GRK4, GPRK2L, GPRK4
Domain Architecture
Description	G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK4) (ITI1).

ICK_MOUSE
θ value	1.68911e-14 (rank : 399)	NC score	0.821875 (rank : 338)
Query Neighborhood Hits	1959	Target Neighborhood Hits	860	Shared Neighborhood Hits	831
SwissProt Accessions	Q9JKV2, Q8K138	Gene names	Ick
Domain Architecture
Description	Serine/threonine-protein kinase ICK (EC 2.7.11.22) (Intestinal cell kinase) (mICK) (MAK-related kinase) (MRK).

LRIG3_MOUSE
θ value	1.68911e-14 (rank : 400)	NC score	0.269277 (rank : 979)
Query Neighborhood Hits	1959	Target Neighborhood Hits	611	Shared Neighborhood Hits	296
SwissProt Accessions	Q6P1C6, Q6ZPE6, Q8BRF0, Q8BS51, Q8C5E4	Gene names	Lrig3, Kiaa3016
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor.

MAST3_HUMAN
θ value	1.68911e-14 (rank : 401)	NC score	0.834067 (rank : 264)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1128	Shared Neighborhood Hits	930
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

MYO3A_MOUSE
θ value	1.68911e-14 (rank : 402)	NC score	0.729670 (rank : 576)
Query Neighborhood Hits	1959	Target Neighborhood Hits	902	Shared Neighborhood Hits	820
SwissProt Accessions	Q8K3H5	Gene names	Myo3a
Domain Architecture
Description	Myosin IIIA (EC 2.7.11.1).

TAOK3_HUMAN
θ value	1.68911e-14 (rank : 403)	NC score	0.785066 (rank : 491)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1494	Shared Neighborhood Hits	882
SwissProt Accessions	Q9H2K8, Q658N1, Q8IUM4, Q9HC79, Q9NZM9, Q9UHG7	Gene names	TAOK3, DPK, JIK, KDS, MAP3K18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3) (Jun kinase-inhibitory kinase) (JNK/SAPK- inhibitory kinase) (Dendritic cell-derived protein kinase) (Cutaneous T-cell lymphoma tumor antigen HD-CL-09) (CTCL tumor antigen HD-CL-09) (Kinase from chicken homolog A) (hKFC-A).

TBK1_MOUSE
θ value	1.68911e-14 (rank : 404)	NC score	0.839088 (rank : 226)
Query Neighborhood Hits	1959	Target Neighborhood Hits	893	Shared Neighborhood Hits	792
SwissProt Accessions	Q9WUN2, Q9CT90, Q9DC03	Gene names	Tbk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (TANK-binding kinase 1) (T2K).

TSSK1_MOUSE
θ value	1.68911e-14 (rank : 405)	NC score	0.853402 (rank : 135)
Query Neighborhood Hits	1959	Target Neighborhood Hits	835	Shared Neighborhood Hits	810
SwissProt Accessions	Q61241	Gene names	Tssk1, Stk22a
Domain Architecture
Description	Testis-specific serine/threonine-protein kinase 1 (EC 2.7.11.1) (TSSK- 1) (Testis-specific kinase 1) (TSK-1) (Serine/threonine-protein kinase 22A).

TSSK4_HUMAN
θ value	1.68911e-14 (rank : 406)	NC score	0.852878 (rank : 139)
Query Neighborhood Hits	1959	Target Neighborhood Hits	836	Shared Neighborhood Hits	822
SwissProt Accessions	Q6SA08	Gene names	TSSK4, C14orf20, STK22E
Domain Architecture	No domain graphic available
Description	Testis-specific serine/threonine-protein kinase 4 (EC 2.7.11.1) (TSSK- 4) (Testis-specific kinase 4) (TSK-4) (Serine/threonine-protein kinase 22E).

CTRO_HUMAN
θ value	2.20605e-14 (rank : 407)	NC score	0.734024 (rank : 568)
Query Neighborhood Hits	1959	Target Neighborhood Hits	2092	Shared Neighborhood Hits	941
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

KPCT_MOUSE
θ value	2.20605e-14 (rank : 408)	NC score	0.832400 (rank : 274)
Query Neighborhood Hits	1959	Target Neighborhood Hits	895	Shared Neighborhood Hits	825
SwissProt Accessions	Q02111	Gene names	Prkcq, Pkcq
Domain Architecture
Description	Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta).

M4K2_HUMAN
θ value	2.20605e-14 (rank : 409)	NC score	0.823502 (rank : 333)
Query Neighborhood Hits	1959	Target Neighborhood Hits	850	Shared Neighborhood Hits	820
SwissProt Accessions	Q12851	Gene names	MAP4K2, GCK, RAB8IP
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Germinal center kinase) (GC kinase) (Rab8-interacting protein) (B lymphocyte serine/threonine-protein kinase).

M4K2_MOUSE
θ value	2.20605e-14 (rank : 410)	NC score	0.823548 (rank : 332)
Query Neighborhood Hits	1959	Target Neighborhood Hits	843	Shared Neighborhood Hits	813
SwissProt Accessions	Q61161	Gene names	Map4k2, Rab8ip
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Germinal center kinase) (GCK) (Rab8-interacting protein).

M4K5_HUMAN
θ value	2.20605e-14 (rank : 411)	NC score	0.818971 (rank : 352)
Query Neighborhood Hits	1959	Target Neighborhood Hits	845	Shared Neighborhood Hits	815
SwissProt Accessions	Q9Y4K4, Q8IYF6	Gene names	MAP4K5
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 5) (MEK kinase kinase 5) (MEKKK 5) (Kinase homologous to SPS1/STE20) (KHS).

MP2K2_MOUSE
θ value	2.20605e-14 (rank : 412)	NC score	0.826679 (rank : 308)
Query Neighborhood Hits	1959	Target Neighborhood Hits	828	Shared Neighborhood Hits	814
SwissProt Accessions	Q63932	Gene names	Map2k2, Mek2, Mkk2, Prkmk2
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 2 (EC 2.7.12.2) (MAP kinase kinase 2) (MAPKK 2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK2).

NEK1_HUMAN
θ value	2.20605e-14 (rank : 413)	NC score	0.845097 (rank : 191)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1129	Shared Neighborhood Hits	862
SwissProt Accessions	Q96PY6, Q9Y594	Gene names	NEK1, KIAA1901
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1) (NY-REN-55 antigen).

TAOK3_MOUSE
θ value	2.20605e-14 (rank : 414)	NC score	0.787473 (rank : 482)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1458	Shared Neighborhood Hits	874
SwissProt Accessions	Q8BYC6, Q3V3B3	Gene names	Taok3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3).

KPCE_MOUSE
θ value	2.88119e-14 (rank : 415)	NC score	0.826464 (rank : 310)
Query Neighborhood Hits	1959	Target Neighborhood Hits	906	Shared Neighborhood Hits	819
SwissProt Accessions	P16054	Gene names	Prkce, Pkce, Pkcea
Domain Architecture
Description	Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon).

M4K5_MOUSE
θ value	2.88119e-14 (rank : 416)	NC score	0.820256 (rank : 345)
Query Neighborhood Hits	1959	Target Neighborhood Hits	839	Shared Neighborhood Hits	810
SwissProt Accessions	Q8BPM2, Q6PEQ2, Q8C3U5, Q8CGF3, Q99LM7, Q9CX73	Gene names	Map4k5
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 5) (MEK kinase kinase 5) (MEKKK 5).

MYOM1_MOUSE
θ value	2.88119e-14 (rank : 417)	NC score	0.353208 (rank : 908)
Query Neighborhood Hits	1959	Target Neighborhood Hits	415	Shared Neighborhood Hits	296
SwissProt Accessions	Q62234	Gene names	Myom1
Domain Architecture
Description	Myomesin-1 (Skelemin).

PCTK2_HUMAN
θ value	2.88119e-14 (rank : 418)	NC score	0.813431 (rank : 376)
Query Neighborhood Hits	1959	Target Neighborhood Hits	837	Shared Neighborhood Hits	811
SwissProt Accessions	Q00537, Q8NEB8	Gene names	PCTK2
Domain Architecture
Description	Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22) (PCTAIRE- motif protein kinase 2).

STK11_HUMAN
θ value	2.88119e-14 (rank : 419)	NC score	0.862851 (rank : 69)
Query Neighborhood Hits	1959	Target Neighborhood Hits	831	Shared Neighborhood Hits	814
SwissProt Accessions	Q15831	Gene names	STK11, LKB1, PJS
Domain Architecture
Description	Serine/threonine-protein kinase 11 (EC 2.7.11.1) (Serine/threonine- protein kinase LKB1) (NY-REN-19 antigen).

DMPK_HUMAN
θ value	3.76295e-14 (rank : 420)	NC score	0.817953 (rank : 358)
Query Neighborhood Hits	1959	Target Neighborhood Hits	944	Shared Neighborhood Hits	821
SwissProt Accessions	Q09013, Q16205	Gene names	DMPK, MDPK
Domain Architecture
Description	Myotonin-protein kinase (EC 2.7.11.1) (Myotonic dystrophy protein kinase) (MDPK) (DM-kinase) (DMK) (DMPK) (MT-PK).

MDGA1_HUMAN
θ value	3.76295e-14 (rank : 421)	NC score	0.352297 (rank : 910)
Query Neighborhood Hits	1959	Target Neighborhood Hits	358	Shared Neighborhood Hits	274
SwissProt Accessions	Q8NFP4, Q8NBE3	Gene names	MDGA1, MAMDC3
Domain Architecture
Description	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 precursor (MAM domain-containing protein 3) (GPI and MAM protein) (Glycosylphosphatidylinositol-MAM) (GPIM).

NCA12_HUMAN
θ value	3.76295e-14 (rank : 422)	NC score	0.389127 (rank : 869)
Query Neighborhood Hits	1959	Target Neighborhood Hits	437	Shared Neighborhood Hits	323
SwissProt Accessions	P13592, P13593	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120) (CD56 antigen).

PASK_HUMAN
θ value	3.76295e-14 (rank : 423)	NC score	0.854635 (rank : 127)
Query Neighborhood Hits	1959	Target Neighborhood Hits	857	Shared Neighborhood Hits	812
SwissProt Accessions	Q96RG2, Q86XH6, Q99763, Q9UFR7	Gene names	PASK, KIAA0135
Domain Architecture
Description	PAS domain-containing serine/threonine-protein kinase (EC 2.7.11.1) (PAS-kinase) (PASKIN) (hPASK).

PCTK2_MOUSE
θ value	3.76295e-14 (rank : 424)	NC score	0.813079 (rank : 378)
Query Neighborhood Hits	1959	Target Neighborhood Hits	836	Shared Neighborhood Hits	811
SwissProt Accessions	Q8K0D0	Gene names	Pctk2
Domain Architecture
Description	Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22) (PCTAIRE- motif protein kinase 2).

ULK2_HUMAN
θ value	3.76295e-14 (rank : 425)	NC score	0.857888 (rank : 103)
Query Neighborhood Hits	1959	Target Neighborhood Hits	979	Shared Neighborhood Hits	876
SwissProt Accessions	Q8IYT8, O75119	Gene names	ULK2, KIAA0623
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2).

ULK2_MOUSE
θ value	3.76295e-14 (rank : 426)	NC score	0.858091 (rank : 100)
Query Neighborhood Hits	1959	Target Neighborhood Hits	943	Shared Neighborhood Hits	865
SwissProt Accessions	Q9QY01, Q80TV7, Q9WTP4	Gene names	Ulk2, Kiaa0623
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2) (Serine/threonine-protein kinase Unc51.2).

KPCD_HUMAN
θ value	4.91457e-14 (rank : 427)	NC score	0.827125 (rank : 303)
Query Neighborhood Hits	1959	Target Neighborhood Hits	900	Shared Neighborhood Hits	821
SwissProt Accessions	Q05655, Q15144	Gene names	PRKCD
Domain Architecture
Description	Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta).

MK04_MOUSE
θ value	4.91457e-14 (rank : 428)	NC score	0.808831 (rank : 404)
Query Neighborhood Hits	1959	Target Neighborhood Hits	852	Shared Neighborhood Hits	818
SwissProt Accessions	Q6P5G0	Gene names	Mapk4, Erk4, Prkm4
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 4 (EC 2.7.11.24) (Extracellular signal-regulated kinase 4) (ERK-4).

MK07_MOUSE
θ value	4.91457e-14 (rank : 429)	NC score	0.811250 (rank : 389)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1054	Shared Neighborhood Hits	931
SwissProt Accessions	Q9WVS8	Gene names	Mapk7, Erk5
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase).

MK12_MOUSE
θ value	4.91457e-14 (rank : 430)	NC score	0.814397 (rank : 374)
Query Neighborhood Hits	1959	Target Neighborhood Hits	835	Shared Neighborhood Hits	814
SwissProt Accessions	O08911, Q9D0M4	Gene names	Mapk12, Sapk3
Domain Architecture
Description	Mitogen-activated protein kinase 12 (EC 2.7.11.24) (Extracellular signal-regulated kinase 6) (ERK-6) (Stress-activated protein kinase 3) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma).

ARAF_MOUSE
θ value	6.41864e-14 (rank : 431)	NC score	0.764867 (rank : 534)
Query Neighborhood Hits	1959	Target Neighborhood Hits	874	Shared Neighborhood Hits	819
SwissProt Accessions	P04627, Q99J44, Q9CTT5, Q9D6R6, Q9DBU7	Gene names	Araf, A-raf, Araf1
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1).

M3K10_HUMAN
θ value	6.41864e-14 (rank : 432)	NC score	0.765378 (rank : 531)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1071	Shared Neighborhood Hits	837
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

M3K1_MOUSE
θ value	6.41864e-14 (rank : 433)	NC score	0.847127 (rank : 170)
Query Neighborhood Hits	1959	Target Neighborhood Hits	952	Shared Neighborhood Hits	857
SwissProt Accessions	P53349, Q60831, Q9R0U3, Q9R256	Gene names	Map3k1, Mekk, Mekk1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1).

M4K1_MOUSE
θ value	6.41864e-14 (rank : 434)	NC score	0.823934 (rank : 327)
Query Neighborhood Hits	1959	Target Neighborhood Hits	858	Shared Neighborhood Hits	827
SwissProt Accessions	P70218, Q8R3R0, Q99K62	Gene names	Map4k1, Hpk1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1) (Hematopoietic progenitor kinase) (HPK).

TESK2_HUMAN
θ value	6.41864e-14 (rank : 435)	NC score	0.781758 (rank : 498)
Query Neighborhood Hits	1959	Target Neighborhood Hits	851	Shared Neighborhood Hits	811
SwissProt Accessions	Q96S53, Q8N520, Q9Y3Q6	Gene names	TESK2
Domain Architecture
Description	Dual specificity testis-specific protein kinase 2 (EC 2.7.12.1) (Testicular protein kinase 2).

KPCD_MOUSE
θ value	8.38298e-14 (rank : 436)	NC score	0.825961 (rank : 315)
Query Neighborhood Hits	1959	Target Neighborhood Hits	888	Shared Neighborhood Hits	818
SwissProt Accessions	P28867, Q91V85, Q9Z333	Gene names	Prkcd, Pkcd
Domain Architecture
Description	Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta).

MK06_HUMAN
θ value	8.38298e-14 (rank : 437)	NC score	0.799038 (rank : 449)
Query Neighborhood Hits	1959	Target Neighborhood Hits	815	Shared Neighborhood Hits	790
SwissProt Accessions	Q16659, Q68DH4, Q8IYN8	Gene names	MAPK6, ERK3, PRKM6
Domain Architecture
Description	Mitogen-activated protein kinase 6 (EC 2.7.11.24) (Extracellular signal-regulated kinase 3) (ERK-3) (MAP kinase isoform p97) (p97- MAPK).

MK06_MOUSE
θ value	8.38298e-14 (rank : 438)	NC score	0.798884 (rank : 451)
Query Neighborhood Hits	1959	Target Neighborhood Hits	818	Shared Neighborhood Hits	791
SwissProt Accessions	Q61532, Q497T9, Q6YKB0, Q7TT30, Q80XH5, Q922U4, Q9JLU6	Gene names	Mapk6, Erk3, Prkm4, Prkm6
Domain Architecture
Description	Mitogen-activated protein kinase 6 (EC 2.7.11.24) (Extracellular signal-regulated kinase 3) (ERK-3).

MP2K2_HUMAN
θ value	8.38298e-14 (rank : 439)	NC score	0.828052 (rank : 298)
Query Neighborhood Hits	1959	Target Neighborhood Hits	830	Shared Neighborhood Hits	815
SwissProt Accessions	P36507	Gene names	MAP2K2, MEK2, MKK2, PRKMK2
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 2 (EC 2.7.12.2) (MAP kinase kinase 2) (MAPKK 2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK2).

PCTK3_HUMAN
θ value	8.38298e-14 (rank : 440)	NC score	0.814908 (rank : 369)
Query Neighborhood Hits	1959	Target Neighborhood Hits	827	Shared Neighborhood Hits	804
SwissProt Accessions	Q07002, Q5VXQ2, Q96F90	Gene names	PCTK3
Domain Architecture
Description	Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22) (PCTAIRE- motif protein kinase 3).

PMYT1_HUMAN
θ value	8.38298e-14 (rank : 441)	NC score	0.822328 (rank : 337)
Query Neighborhood Hits	1959	Target Neighborhood Hits	814	Shared Neighborhood Hits	795
SwissProt Accessions	Q99640, O14731, Q7LE24, Q8TCM9	Gene names	PKMYT1, MYT1
Domain Architecture	No domain graphic available
Description	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase).

CD2L5_HUMAN
θ value	1.09485e-13 (rank : 442)	NC score	0.809697 (rank : 400)
Query Neighborhood Hits	1959	Target Neighborhood Hits	987	Shared Neighborhood Hits	859
SwissProt Accessions	Q14004, Q6DKQ9, Q75MH4, Q75MH5, Q96JN4, Q9H4A0, Q9H4A1, Q9UDR4	Gene names	CDC2L5, CDC2L, CHED, KIAA1791
Domain Architecture
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5) (Cholinesterase-related cell division controller).

CD2L5_MOUSE
θ value	1.09485e-13 (rank : 443)	NC score	0.810020 (rank : 399)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1011	Shared Neighborhood Hits	877
SwissProt Accessions	Q69ZA1, Q80V11, Q8BZG1, Q8K0A4	Gene names	Cdc2l5, Kiaa1791
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5).

MK07_HUMAN
θ value	1.09485e-13 (rank : 444)	NC score	0.810675 (rank : 393)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1087	Shared Neighborhood Hits	944
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

MK13_MOUSE
θ value	1.09485e-13 (rank : 445)	NC score	0.810029 (rank : 398)
Query Neighborhood Hits	1959	Target Neighborhood Hits	832	Shared Neighborhood Hits	815
SwissProt Accessions	Q9Z1B7, Q99M57	Gene names	Mapk13, Serk4
Domain Architecture
Description	Mitogen-activated protein kinase 13 (EC 2.7.11.24) (Stress-activated protein kinase 4) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta).

ARAF_HUMAN
θ value	1.42992e-13 (rank : 446)	NC score	0.765288 (rank : 532)
Query Neighborhood Hits	1959	Target Neighborhood Hits	924	Shared Neighborhood Hits	834
SwissProt Accessions	P10398, P07557, Q5H9B3	Gene names	ARAF, ARAF1, PKS, PKS2
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (A- raf-1) (Proto-oncogene Pks).

PCTK3_MOUSE
θ value	1.42992e-13 (rank : 447)	NC score	0.816978 (rank : 359)
Query Neighborhood Hits	1959	Target Neighborhood Hits	834	Shared Neighborhood Hits	811
SwissProt Accessions	Q04899	Gene names	Pctk3
Domain Architecture
Description	Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22) (PCTAIRE- motif protein kinase 3).

TSSK1_HUMAN
θ value	1.42992e-13 (rank : 448)	NC score	0.851400 (rank : 150)
Query Neighborhood Hits	1959	Target Neighborhood Hits	840	Shared Neighborhood Hits	811
SwissProt Accessions	Q9BXA7	Gene names	TSSK1, SPOGA1, SPOGA4, STK22A, STK22D
Domain Architecture
Description	Testis-specific serine/threonine-protein kinase 1 (EC 2.7.11.1) (TSSK- 1) (Testis-specific kinase 1) (TSK-1) (Serine/threonine-protein kinase 22A).

MYPC3_HUMAN
θ value	1.86753e-13 (rank : 449)	NC score	0.348366 (rank : 913)
Query Neighborhood Hits	1959	Target Neighborhood Hits	318	Shared Neighborhood Hits	263
SwissProt Accessions	Q14896, Q16410, Q6R2F7, Q9UE27, Q9UM53	Gene names	MYBPC3
Domain Architecture
Description	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform).

NRK_HUMAN
θ value	1.86753e-13 (rank : 450)	NC score	0.814918 (rank : 368)
Query Neighborhood Hits	1959	Target Neighborhood Hits	931	Shared Neighborhood Hits	834
SwissProt Accessions	Q7Z2Y5, Q32ND6, Q5H9K2, Q6ZMP2	Gene names	NRK
Domain Architecture	No domain graphic available
Description	Nik-related protein kinase (EC 2.7.11.1).

TESK2_MOUSE
θ value	1.86753e-13 (rank : 451)	NC score	0.781719 (rank : 499)
Query Neighborhood Hits	1959	Target Neighborhood Hits	833	Shared Neighborhood Hits	800
SwissProt Accessions	Q8VCT9	Gene names	Tesk2
Domain Architecture
Description	Dual specificity testis-specific protein kinase 2 (EC 2.7.12.1) (Testicular protein kinase 2).

CDK3_MOUSE
θ value	2.43908e-13 (rank : 452)	NC score	0.825776 (rank : 317)
Query Neighborhood Hits	1959	Target Neighborhood Hits	829	Shared Neighborhood Hits	814
SwissProt Accessions	Q80YP0	Gene names	Cdk3
Domain Architecture	No domain graphic available
Description	Truncated cell division protein kinase 3 homolog.

KPCL_HUMAN
θ value	2.43908e-13 (rank : 453)	NC score	0.826863 (rank : 307)
Query Neighborhood Hits	1959	Target Neighborhood Hits	887	Shared Neighborhood Hits	809
SwissProt Accessions	P24723, Q16246	Gene names	PRKCH, PKCL
Domain Architecture
Description	Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta) (PKC-L).

NEK7_HUMAN
θ value	2.43908e-13 (rank : 454)	NC score	0.839724 (rank : 221)
Query Neighborhood Hits	1959	Target Neighborhood Hits	846	Shared Neighborhood Hits	824
SwissProt Accessions	Q8TDX7	Gene names	NEK7
Domain Architecture
Description	Serine/threonine-protein kinase Nek7 (EC 2.7.11.1) (NimA-related protein kinase 7).

RAF1_HUMAN
θ value	2.43908e-13 (rank : 455)	NC score	0.768644 (rank : 525)
Query Neighborhood Hits	1959	Target Neighborhood Hits	886	Shared Neighborhood Hits	823
SwissProt Accessions	P04049	Gene names	RAF1, RAF
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

RAF1_MOUSE
θ value	2.43908e-13 (rank : 456)	NC score	0.769101 (rank : 523)
Query Neighborhood Hits	1959	Target Neighborhood Hits	886	Shared Neighborhood Hits	826
SwissProt Accessions	Q99N57, Q91WH1	Gene names	Raf1, Craf
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

STK25_MOUSE
θ value	2.43908e-13 (rank : 457)	NC score	0.827895 (rank : 300)
Query Neighborhood Hits	1959	Target Neighborhood Hits	851	Shared Neighborhood Hits	822
SwissProt Accessions	Q9Z2W1	Gene names	Stk25, Sok1
Domain Architecture
Description	Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Sterile 20/oxidant stress-response kinase 1) (Ste20/oxidant stress response kinase 1) (SOK-1) (Ste20-like kinase).

NEK7_MOUSE
θ value	3.18553e-13 (rank : 458)	NC score	0.839707 (rank : 222)
Query Neighborhood Hits	1959	Target Neighborhood Hits	847	Shared Neighborhood Hits	825
SwissProt Accessions	Q9ES74, Q3UEV7	Gene names	Nek7
Domain Architecture
Description	Serine/threonine-protein kinase Nek7 (EC 2.7.11.1) (NimA-related protein kinase 7).

NRK_MOUSE
θ value	3.18553e-13 (rank : 459)	NC score	0.813563 (rank : 375)
Query Neighborhood Hits	1959	Target Neighborhood Hits	899	Shared Neighborhood Hits	832
SwissProt Accessions	Q9R0G8, Q6NV55, Q8C9S9, Q9R0S4	Gene names	Nrk, Nesk
Domain Architecture	No domain graphic available
Description	Nik-related protein kinase (EC 2.7.11.1) (Nck-interacting kinase-like embryo specific kinase) (NIK-like embryo-specific kinase) (NESK).

SRMS_MOUSE
θ value	3.18553e-13 (rank : 460)	NC score	0.689470 (rank : 636)
Query Neighborhood Hits	1959	Target Neighborhood Hits	964	Shared Neighborhood Hits	816
SwissProt Accessions	Q62270, Q62360, Q923M5	Gene names	Srms, Srm
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70).

MKNK1_HUMAN
θ value	4.16044e-13 (rank : 461)	NC score	0.812141 (rank : 384)
Query Neighborhood Hits	1959	Target Neighborhood Hits	701	Shared Neighborhood Hits	684
SwissProt Accessions	Q9BUB5, O00312, Q5TC06, Q6V0N6	Gene names	MKNK1, MNK1
Domain Architecture
Description	MAP kinase-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (Mnk1).

PCTK1_HUMAN
θ value	4.16044e-13 (rank : 462)	NC score	0.816159 (rank : 362)
Query Neighborhood Hits	1959	Target Neighborhood Hits	832	Shared Neighborhood Hits	810
SwissProt Accessions	Q00536	Gene names	PCTK1
Domain Architecture
Description	Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22) (PCTAIRE- motif protein kinase 1).

PCTK1_MOUSE
θ value	4.16044e-13 (rank : 463)	NC score	0.815921 (rank : 364)
Query Neighborhood Hits	1959	Target Neighborhood Hits	832	Shared Neighborhood Hits	810
SwissProt Accessions	Q04735	Gene names	Pctk1, Crk5
Domain Architecture
Description	Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22) (PCTAIRE- motif protein kinase 1) (CRK5).

CCRK_MOUSE
θ value	5.43371e-13 (rank : 464)	NC score	0.814684 (rank : 371)
Query Neighborhood Hits	1959	Target Neighborhood Hits	832	Shared Neighborhood Hits	815
SwissProt Accessions	Q9JHU3, Q5EDC2	Gene names	Ccrk, Cdch
Domain Architecture	No domain graphic available
Description	Cell cycle-related kinase (EC 2.7.11.22) (Cyclin-kinase-activating kinase p42) (CDK-activating kinase p42) (CAK-kinase p42) (CDK-related protein kinase PNQLARE) (Cyclin-dependent protein kinase H).

CDK9_HUMAN
θ value	5.43371e-13 (rank : 465)	NC score	0.802645 (rank : 438)
Query Neighborhood Hits	1959	Target Neighborhood Hits	822	Shared Neighborhood Hits	805
SwissProt Accessions	P50750, Q5JU24, Q5JU25, Q5U006, Q96TF1	Gene names	CDK9, CDC2L4
Domain Architecture
Description	Cell division protein kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (Cyclin- dependent kinase 9) (Serine/threonine-protein kinase PITALRE) (C-2K) (Cell division cycle 2-like protein kinase 4).

GSK3A_HUMAN
θ value	5.43371e-13 (rank : 466)	NC score	0.814498 (rank : 373)
Query Neighborhood Hits	1959	Target Neighborhood Hits	835	Shared Neighborhood Hits	794
SwissProt Accessions	P49840, O14959	Gene names	GSK3A
Domain Architecture
Description	Glycogen synthase kinase-3 alpha (EC 2.7.11.26) (GSK-3 alpha).

M4K4_MOUSE
θ value	5.43371e-13 (rank : 467)	NC score	0.789108 (rank : 476)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1560	Shared Neighborhood Hits	908
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

MK12_HUMAN
θ value	5.43371e-13 (rank : 468)	NC score	0.812883 (rank : 379)
Query Neighborhood Hits	1959	Target Neighborhood Hits	830	Shared Neighborhood Hits	812
SwissProt Accessions	P53778, Q14260, Q99588, Q99672	Gene names	MAPK12, ERK6, SAPK3
Domain Architecture
Description	Mitogen-activated protein kinase 12 (EC 2.7.11.24) (Extracellular signal-regulated kinase 6) (ERK-6) (ERK5) (Stress-activated protein kinase 3) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma).

STK25_HUMAN
θ value	5.43371e-13 (rank : 469)	NC score	0.828273 (rank : 297)
Query Neighborhood Hits	1959	Target Neighborhood Hits	853	Shared Neighborhood Hits	822
SwissProt Accessions	O00506, Q15522, Q5BJF1	Gene names	STK25, SOK1, YSK1
Domain Architecture
Description	Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Sterile 20/oxidant stress-response kinase 1) (Ste20/oxidant stress response kinase 1) (SOK-1) (Ste20-like kinase).

CHL1_MOUSE
θ value	7.09661e-13 (rank : 470)	NC score	0.376595 (rank : 892)
Query Neighborhood Hits	1959	Target Neighborhood Hits	402	Shared Neighborhood Hits	310
SwissProt Accessions	P70232, Q8BS24, Q8C6W0, Q8C823, Q8VBY7	Gene names	Chl1, Call
Domain Architecture	No domain graphic available
Description	Neural cell adhesion molecule L1-like protein precursor (Cell adhesion molecule with homology to L1CAM) (Close homolog of L1) (Chl1-like protein).

OXSR1_HUMAN
θ value	7.09661e-13 (rank : 471)	NC score	0.830574 (rank : 283)
Query Neighborhood Hits	1959	Target Neighborhood Hits	874	Shared Neighborhood Hits	833
SwissProt Accessions	O95747, Q3LR53, Q7Z501, Q9UPQ1	Gene names	OXSR1, KIAA1101, OSR1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress- responsive 1 protein).

CCRK_HUMAN
θ value	9.26847e-13 (rank : 472)	NC score	0.815258 (rank : 367)
Query Neighborhood Hits	1959	Target Neighborhood Hits	835	Shared Neighborhood Hits	817
SwissProt Accessions	Q8IZL9, Q5EDC4, Q5VYW1, Q9BUF4	Gene names	CCRK, CDCH
Domain Architecture	No domain graphic available
Description	Cell cycle-related kinase (EC 2.7.11.22) (Cyclin-kinase-activating kinase p42) (CDK-activating kinase p42) (CAK-kinase p42) (Cyclin- dependent protein kinase H).

MOK_HUMAN
θ value	9.26847e-13 (rank : 473)	NC score	0.807527 (rank : 410)
Query Neighborhood Hits	1959	Target Neighborhood Hits	807	Shared Neighborhood Hits	793
SwissProt Accessions	Q9UQ07, Q92790, Q93067	Gene names	RAGE, MOK, RAGE1
Domain Architecture
Description	MAPK/MAK/MRK overlapping kinase (EC 2.7.11.22) (MOK protein kinase) (Renal tumor antigen 1) (RAGE-1).

OPCM_HUMAN
θ value	9.26847e-13 (rank : 474)	NC score	0.367533 (rank : 895)
Query Neighborhood Hits	1959	Target Neighborhood Hits	332	Shared Neighborhood Hits	276
SwissProt Accessions	Q14982	Gene names	OPCML, OBCAM
Domain Architecture
Description	Opioid-binding protein/cell adhesion molecule precursor (OBCAM) (Opioid-binding cell adhesion molecule) (OPCML).

CDK9_MOUSE
θ value	1.2105e-12 (rank : 475)	NC score	0.802008 (rank : 440)
Query Neighborhood Hits	1959	Target Neighborhood Hits	822	Shared Neighborhood Hits	805
SwissProt Accessions	Q99J95, Q3U002, Q3UMY2, Q3UPT3, Q3UQI6, Q8BTN0	Gene names	Cdk9
Domain Architecture	No domain graphic available
Description	Cell division protein kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (Cyclin- dependent kinase 9).

M3K4_MOUSE
θ value	1.2105e-12 (rank : 476)	NC score	0.839747 (rank : 220)
Query Neighborhood Hits	1959	Target Neighborhood Hits	924	Shared Neighborhood Hits	836
SwissProt Accessions	O08648, O08649, O70124	Gene names	Map3k4, Mekk4
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4).

MP2K5_MOUSE
θ value	1.2105e-12 (rank : 477)	NC score	0.825343 (rank : 319)
Query Neighborhood Hits	1959	Target Neighborhood Hits	840	Shared Neighborhood Hits	820
SwissProt Accessions	Q9WVS7, Q8CFM3, Q8K360, Q9D222	Gene names	Map2k5, Mek5, Mkk5, Prkmk5
Domain Architecture	No domain graphic available
Description	Dual specificity mitogen-activated protein kinase kinase 5 (EC 2.7.12.2) (MAP kinase kinase 5) (MAPKK 5) (MAPK/ERK kinase 5).

MYO3A_HUMAN
θ value	1.2105e-12 (rank : 478)	NC score	0.722415 (rank : 588)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1033	Shared Neighborhood Hits	838
SwissProt Accessions	Q8NEV4, Q8WX17, Q9NYS8	Gene names	MYO3A
Domain Architecture
Description	Myosin IIIA (EC 2.7.11.1).

PIM2_MOUSE
θ value	1.2105e-12 (rank : 479)	NC score	0.837786 (rank : 234)
Query Neighborhood Hits	1959	Target Neighborhood Hits	809	Shared Neighborhood Hits	792
SwissProt Accessions	Q62070, Q62071, Q62072	Gene names	Pim2, Pim-2
Domain Architecture
Description	Serine/threonine-protein kinase Pim-2 (EC 2.7.11.1).

LATS1_HUMAN
θ value	1.58096e-12 (rank : 480)	NC score	0.805040 (rank : 430)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1057	Shared Neighborhood Hits	888
SwissProt Accessions	O95835, Q6PKD0	Gene names	LATS1, WARTS
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts).

NCA11_MOUSE
θ value	1.58096e-12 (rank : 481)	NC score	0.390058 (rank : 867)
Query Neighborhood Hits	1959	Target Neighborhood Hits	661	Shared Neighborhood Hits	438
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

NCA12_MOUSE
θ value	1.58096e-12 (rank : 482)	NC score	0.385725 (rank : 881)
Query Neighborhood Hits	1959	Target Neighborhood Hits	399	Shared Neighborhood Hits	307
SwissProt Accessions	P13594, Q61950	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120).

OXSR1_MOUSE
θ value	1.58096e-12 (rank : 483)	NC score	0.830100 (rank : 288)
Query Neighborhood Hits	1959	Target Neighborhood Hits	865	Shared Neighborhood Hits	827
SwissProt Accessions	Q6P9R2, Q8BVZ9, Q8C0B9	Gene names	Oxsr1, Osr1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress- responsive 1 protein).

TLK2_HUMAN
θ value	1.58096e-12 (rank : 484)	NC score	0.823047 (rank : 334)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1044	Shared Neighborhood Hits	792
SwissProt Accessions	Q86UE8, Q9UKI7, Q9Y4F7	Gene names	TLK2
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (Tousled- like kinase 2) (PKU-alpha).

TLK2_MOUSE
θ value	1.58096e-12 (rank : 485)	NC score	0.820870 (rank : 344)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1088	Shared Neighborhood Hits	799
SwissProt Accessions	O55047, Q9D5Y5	Gene names	Tlk2
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (Tousled- like kinase 2).

TSSK2_MOUSE
θ value	1.58096e-12 (rank : 486)	NC score	0.849177 (rank : 160)
Query Neighborhood Hits	1959	Target Neighborhood Hits	819	Shared Neighborhood Hits	798
SwissProt Accessions	O54863	Gene names	Tssk2, Stk22b
Domain Architecture
Description	Testis-specific serine/threonine-protein kinase 2 (EC 2.7.11.1) (TSSK- 2) (Testis-specific kinase 2) (TSK-2) (Serine/threonine-protein kinase 22B).

GSK3B_HUMAN
θ value	2.0648e-12 (rank : 487)	NC score	0.812552 (rank : 382)
Query Neighborhood Hits	1959	Target Neighborhood Hits	801	Shared Neighborhood Hits	788
SwissProt Accessions	P49841, Q9BWH3, Q9UL47	Gene names	GSK3B
Domain Architecture
Description	Glycogen synthase kinase-3 beta (EC 2.7.11.26) (GSK-3 beta).

GSK3B_MOUSE
θ value	2.0648e-12 (rank : 488)	NC score	0.812555 (rank : 381)
Query Neighborhood Hits	1959	Target Neighborhood Hits	800	Shared Neighborhood Hits	788
SwissProt Accessions	Q9WV60	Gene names	Gsk3b
Domain Architecture
Description	Glycogen synthase kinase-3 beta (EC 2.7.11.26) (GSK-3 beta).

M3K7_HUMAN
θ value	2.0648e-12 (rank : 489)	NC score	0.780494 (rank : 502)
Query Neighborhood Hits	1959	Target Neighborhood Hits	892	Shared Neighborhood Hits	814
SwissProt Accessions	O43318, O43317, O43319, Q5TDN2, Q5TDN3	Gene names	MAP3K7, TAK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta- activated kinase 1).

M3K7_MOUSE
θ value	2.0648e-12 (rank : 490)	NC score	0.780615 (rank : 501)
Query Neighborhood Hits	1959	Target Neighborhood Hits	892	Shared Neighborhood Hits	815
SwissProt Accessions	Q62073	Gene names	Map3k7, Tak1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta- activated kinase 1).

MOK_MOUSE
θ value	2.0648e-12 (rank : 491)	NC score	0.805341 (rank : 425)
Query Neighborhood Hits	1959	Target Neighborhood Hits	796	Shared Neighborhood Hits	785
SwissProt Accessions	Q9WVS4, Q8CFU4	Gene names	Rage, Mok
Domain Architecture
Description	MAPK/MAK/MRK overlapping kinase (EC 2.7.11.22) (MOK protein kinase).

TLK1_HUMAN
θ value	2.0648e-12 (rank : 492)	NC score	0.824248 (rank : 325)
Query Neighborhood Hits	1959	Target Neighborhood Hits	967	Shared Neighborhood Hits	771
SwissProt Accessions	Q9UKI8, Q14150, Q8N591, Q9NYH2, Q9Y4F6	Gene names	TLK1, KIAA0137
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1) (Tousled- like kinase 1) (PKU-beta).

TLK1_MOUSE
θ value	2.0648e-12 (rank : 493)	NC score	0.824236 (rank : 326)
Query Neighborhood Hits	1959	Target Neighborhood Hits	947	Shared Neighborhood Hits	768
SwissProt Accessions	Q8C0V0	Gene names	Tlk1
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1) (Tousled- like kinase 1).

WNK1_HUMAN
θ value	2.0648e-12 (rank : 494)	NC score	0.795874 (rank : 461)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1158	Shared Neighborhood Hits	885
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

WNK1_MOUSE
θ value	2.0648e-12 (rank : 495)	NC score	0.794266 (rank : 463)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1179	Shared Neighborhood Hits	890
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

WNK3_HUMAN
θ value	2.0648e-12 (rank : 496)	NC score	0.801369 (rank : 443)
Query Neighborhood Hits	1959	Target Neighborhood Hits	948	Shared Neighborhood Hits	782
SwissProt Accessions	Q9BYP7, Q9HCK6	Gene names	WNK3, KIAA1566, PRKWNK3
Domain Architecture
Description	Serine/threonine-protein kinase WNK3 (EC 2.7.11.1) (Protein kinase with no lysine 3) (Protein kinase, lysine-deficient 3).

BTK_HUMAN
θ value	2.69671e-12 (rank : 497)	NC score	0.686988 (rank : 644)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1026	Shared Neighborhood Hits	815
SwissProt Accessions	Q06187	Gene names	BTK, AGMX1, ATK, BPK
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK).

E2AK2_MOUSE
θ value	2.69671e-12 (rank : 498)	NC score	0.839167 (rank : 225)
Query Neighborhood Hits	1959	Target Neighborhood Hits	864	Shared Neighborhood Hits	824
SwissProt Accessions	Q03963, Q61742, Q62026	Gene names	Eif2ak2, Pkr, Prkr, Tik
Domain Architecture
Description	Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Interferon-inducible RNA-dependent protein kinase) (Protein kinase RNA-activated) (PKR) (p68 kinase) (P1/eIF-2A protein kinase) (Serine/threonine-protein kinase TIK).

M3K14_MOUSE
θ value	2.69671e-12 (rank : 499)	NC score	0.836561 (rank : 245)
Query Neighborhood Hits	1959	Target Neighborhood Hits	889	Shared Neighborhood Hits	824
SwissProt Accessions	Q9WUL6	Gene names	Map3k14, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF- kappa beta-inducing kinase) (Serine/threonine-protein kinase NIK).

M3K4_HUMAN
θ value	2.69671e-12 (rank : 500)	NC score	0.840704 (rank : 216)
Query Neighborhood Hits	1959	Target Neighborhood Hits	911	Shared Neighborhood Hits	836
SwissProt Accessions	Q9Y6R4, Q92612	Gene names	MAP3K4, KIAA0213, MAPKKK4, MEKK4, MTK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4) (MAP three kinase 1).

BTK_MOUSE
θ value	3.52202e-12 (rank : 501)	NC score	0.686524 (rank : 645)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1017	Shared Neighborhood Hits	814
SwissProt Accessions	P35991, Q61365	Gene names	Btk, Bpk
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB).

MP2K1_HUMAN
θ value	3.52202e-12 (rank : 502)	NC score	0.826284 (rank : 313)
Query Neighborhood Hits	1959	Target Neighborhood Hits	826	Shared Neighborhood Hits	812
SwissProt Accessions	Q02750	Gene names	MAP2K1, MEK1, PRKMK1
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 1 (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1).

MP2K1_MOUSE
θ value	3.52202e-12 (rank : 503)	NC score	0.826183 (rank : 314)
Query Neighborhood Hits	1959	Target Neighborhood Hits	826	Shared Neighborhood Hits	812
SwissProt Accessions	P31938	Gene names	Map2k1, Mek1, Prkmk1
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 1 (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1).

NEK6_HUMAN
θ value	3.52202e-12 (rank : 504)	NC score	0.842326 (rank : 207)
Query Neighborhood Hits	1959	Target Neighborhood Hits	848	Shared Neighborhood Hits	825
SwissProt Accessions	Q9HC98, Q96E83, Q9ULX2	Gene names	NEK6
Domain Architecture
Description	Serine/threonine-protein kinase Nek6 (EC 2.7.11.1) (NimA-related protein kinase 6) (Protein kinase SID6-1512).

NEK6_MOUSE
θ value	3.52202e-12 (rank : 505)	NC score	0.842179 (rank : 208)
Query Neighborhood Hits	1959	Target Neighborhood Hits	851	Shared Neighborhood Hits	825
SwissProt Accessions	Q9ES70, Q3TCE9, Q8C6E6, Q9D0E2, Q9DBI8	Gene names	Nek6
Domain Architecture
Description	Serine/threonine-protein kinase Nek6 (EC 2.7.11.1) (NimA-related protein kinase 6).

KPCT_HUMAN
θ value	4.59992e-12 (rank : 506)	NC score	0.832227 (rank : 275)
Query Neighborhood Hits	1959	Target Neighborhood Hits	897	Shared Neighborhood Hits	827
SwissProt Accessions	Q04759, Q3MJF1, Q64FY5, Q9H508, Q9H549	Gene names	PRKCQ, PRKCT
Domain Architecture
Description	Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta).

M3K9_HUMAN
θ value	4.59992e-12 (rank : 507)	NC score	0.765521 (rank : 529)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1123	Shared Neighborhood Hits	871
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

MK04_HUMAN
θ value	4.59992e-12 (rank : 508)	NC score	0.809151 (rank : 402)
Query Neighborhood Hits	1959	Target Neighborhood Hits	837	Shared Neighborhood Hits	815
SwissProt Accessions	P31152	Gene names	MAPK4, ERK4, PRKM4
Domain Architecture
Description	Mitogen-activated protein kinase 4 (EC 2.7.11.24) (Extracellular signal-regulated kinase 4) (ERK-4) (MAP kinase isoform p63) (p63- MAPK).

NEK9_HUMAN
θ value	4.59992e-12 (rank : 509)	NC score	0.825320 (rank : 320)
Query Neighborhood Hits	1959	Target Neighborhood Hits	900	Shared Neighborhood Hits	833
SwissProt Accessions	Q8TD19, Q52LK6, Q8NCN0, Q8TCY4, Q9UPI4, Q9Y6S4, Q9Y6S5, Q9Y6S6	Gene names	NEK9, KIAA1995, NEK8, NERCC
Domain Architecture
Description	Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (NimA-related protein kinase 9) (Never in mitosis A-related kinase 9) (Nercc1 kinase) (NIMA-related kinase 8) (Nek8).

NEK9_MOUSE
θ value	4.59992e-12 (rank : 510)	NC score	0.824643 (rank : 323)
Query Neighborhood Hits	1959	Target Neighborhood Hits	890	Shared Neighborhood Hits	829
SwissProt Accessions	Q8K1R7, Q8R3P1	Gene names	Nek9, Nercc
Domain Architecture
Description	Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (NimA-related protein kinase 9) (Never in mitosis A-related kinase 9).

CDK6_HUMAN
θ value	6.00763e-12 (rank : 511)	NC score	0.814738 (rank : 370)
Query Neighborhood Hits	1959	Target Neighborhood Hits	837	Shared Neighborhood Hits	815
SwissProt Accessions	Q00534	Gene names	CDK6
Domain Architecture
Description	Cell division protein kinase 6 (EC 2.7.11.22) (Serine/threonine- protein kinase PLSTIRE).

CDK6_MOUSE
θ value	6.00763e-12 (rank : 512)	NC score	0.815308 (rank : 366)
Query Neighborhood Hits	1959	Target Neighborhood Hits	837	Shared Neighborhood Hits	815
SwissProt Accessions	Q64261, Q9R1D2, Q9R1D3	Gene names	Cdk6, Crk2
Domain Architecture
Description	Cell division protein kinase 6 (EC 2.7.11.22) (Serine/threonine- protein kinase PLSTIRE) (CRK2).

CDON_HUMAN
θ value	6.00763e-12 (rank : 513)	NC score	0.388675 (rank : 871)
Query Neighborhood Hits	1959	Target Neighborhood Hits	412	Shared Neighborhood Hits	297
SwissProt Accessions	Q4KMG0, O14631	Gene names	CDON, CDO
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

ERN2_MOUSE
θ value	6.00763e-12 (rank : 514)	NC score	0.805227 (rank : 428)
Query Neighborhood Hits	1959	Target Neighborhood Hits	825	Shared Neighborhood Hits	803
SwissProt Accessions	Q9Z2E3	Gene names	Ern2, Ire2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase/endoribonuclease IRE2 precursor (Inositol-requiring protein 2) (IRE1b) (Ire1-beta) (Endoplasmic reticulum-to-nucleus signaling 2) (mIre1) [Includes: Serine/threonine- protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)].

M3K14_HUMAN
θ value	6.00763e-12 (rank : 515)	NC score	0.838077 (rank : 230)
Query Neighborhood Hits	1959	Target Neighborhood Hits	887	Shared Neighborhood Hits	835
SwissProt Accessions	Q99558, Q8IYN1	Gene names	MAP3K14, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF- kappa beta-inducing kinase) (Serine/threonine-protein kinase NIK) (HsNIK).

ACK1_HUMAN
θ value	7.84624e-12 (rank : 516)	NC score	0.675012 (rank : 667)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1140	Shared Neighborhood Hits	963
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

ACK1_MOUSE
θ value	7.84624e-12 (rank : 517)	NC score	0.673019 (rank : 671)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1080	Shared Neighborhood Hits	935
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

CTRO_MOUSE
θ value	7.84624e-12 (rank : 518)	NC score	0.713633 (rank : 600)
Query Neighborhood Hits	1959	Target Neighborhood Hits	2344	Shared Neighborhood Hits	967
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

PIM1_HUMAN
θ value	7.84624e-12 (rank : 519)	NC score	0.835469 (rank : 246)
Query Neighborhood Hits	1959	Target Neighborhood Hits	797	Shared Neighborhood Hits	782
SwissProt Accessions	P11309, Q38RT9, Q96RG3	Gene names	PIM1
Domain Architecture
Description	Proto-oncogene serine/threonine-protein kinase Pim-1 (EC 2.7.11.1).

HIPK4_HUMAN
θ value	1.02475e-11 (rank : 520)	NC score	0.797814 (rank : 454)
Query Neighborhood Hits	1959	Target Neighborhood Hits	799	Shared Neighborhood Hits	786
SwissProt Accessions	Q8NE63	Gene names	HIPK4
Domain Architecture	No domain graphic available
Description	Homeodomain-interacting protein kinase 4 (EC 2.7.11.1).

MYOM1_HUMAN
θ value	1.02475e-11 (rank : 521)	NC score	0.346255 (rank : 914)
Query Neighborhood Hits	1959	Target Neighborhood Hits	405	Shared Neighborhood Hits	283
SwissProt Accessions	P52179	Gene names	MYOM1
Domain Architecture
Description	Myomesin-1 (190 kDa titin-associated protein) (190 kDa connectin- associated protein).

MYOM2_HUMAN
θ value	1.02475e-11 (rank : 522)	NC score	0.355730 (rank : 905)
Query Neighborhood Hits	1959	Target Neighborhood Hits	341	Shared Neighborhood Hits	267
SwissProt Accessions	P54296	Gene names	MYOM2
Domain Architecture
Description	Myomesin-2 (M-protein) (165 kDa titin-associated protein) (165 kDa connectin-associated protein).

TEC_HUMAN
θ value	1.02475e-11 (rank : 523)	NC score	0.695506 (rank : 625)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1006	Shared Neighborhood Hits	816
SwissProt Accessions	P42680	Gene names	TEC, PSCTK4
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

TEC_MOUSE
θ value	1.02475e-11 (rank : 524)	NC score	0.700543 (rank : 615)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1006	Shared Neighborhood Hits	813
SwissProt Accessions	P24604, Q9R1M9, Q9WVN0, Q9WVN1, Q9WVN2, Q9WVN3	Gene names	Tec
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

WNK2_HUMAN
θ value	1.02475e-11 (rank : 525)	NC score	0.794083 (rank : 464)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1407	Shared Neighborhood Hits	1022
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

ERN2_HUMAN
θ value	1.33837e-11 (rank : 526)	NC score	0.808037 (rank : 408)
Query Neighborhood Hits	1959	Target Neighborhood Hits	844	Shared Neighborhood Hits	814
SwissProt Accessions	Q76MJ5, Q6ZNC0	Gene names	ERN2, IRE2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase/endoribonuclease IRE2 precursor (Inositol-requiring protein 2) (hIRE2p) (IRE1b) (Ire1-beta) (Endoplasmic reticulum-to-nucleus signaling 2) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)].

MK13_HUMAN
θ value	1.33837e-11 (rank : 527)	NC score	0.808373 (rank : 407)
Query Neighborhood Hits	1959	Target Neighborhood Hits	829	Shared Neighborhood Hits	813
SwissProt Accessions	O15264, O14739, O15124, Q9UNU0	Gene names	MAPK13, PRKM13, SAPK4
Domain Architecture
Description	Mitogen-activated protein kinase 13 (EC 2.7.11.24) (Stress-activated protein kinase 4) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta).

PIM3_HUMAN
θ value	1.33837e-11 (rank : 528)	NC score	0.834836 (rank : 256)
Query Neighborhood Hits	1959	Target Neighborhood Hits	789	Shared Neighborhood Hits	774
SwissProt Accessions	Q86V86, Q68BM2	Gene names	PIM3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase Pim-3 (EC 2.7.11.1).

CHL1_HUMAN
θ value	1.74796e-11 (rank : 529)	NC score	0.376655 (rank : 891)
Query Neighborhood Hits	1959	Target Neighborhood Hits	413	Shared Neighborhood Hits	317
SwissProt Accessions	O00533, Q2M3G2, Q59FY0	Gene names	CHL1, CALL
Domain Architecture	No domain graphic available
Description	Neural cell adhesion molecule L1-like protein precursor (Close homolog of L1).

DYRK3_HUMAN
θ value	1.74796e-11 (rank : 530)	NC score	0.792781 (rank : 467)
Query Neighborhood Hits	1959	Target Neighborhood Hits	798	Shared Neighborhood Hits	784
SwissProt Accessions	O43781	Gene names	DYRK3
Domain Architecture
Description	Dual specificity tyrosine-phosphorylation-regulated kinase 3 (EC 2.7.12.1).

SBK1_HUMAN
θ value	1.74796e-11 (rank : 531)	NC score	0.854352 (rank : 128)
Query Neighborhood Hits	1959	Target Neighborhood Hits	828	Shared Neighborhood Hits	807
SwissProt Accessions	Q52WX2	Gene names	SBK1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SBK1 (EC 2.7.11.1) (SH3-binding kinase 1).

M3K11_HUMAN
θ value	2.28291e-11 (rank : 532)	NC score	0.766594 (rank : 527)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1136	Shared Neighborhood Hits	896
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

PMYT1_MOUSE
θ value	2.28291e-11 (rank : 533)	NC score	0.826959 (rank : 305)
Query Neighborhood Hits	1959	Target Neighborhood Hits	910	Shared Neighborhood Hits	850
SwissProt Accessions	Q9ESG9, Q8R3L4	Gene names	Pkmyt1, Myt1
Domain Architecture	No domain graphic available
Description	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase).

SBK1_MOUSE
θ value	2.28291e-11 (rank : 534)	NC score	0.855590 (rank : 121)
Query Neighborhood Hits	1959	Target Neighborhood Hits	824	Shared Neighborhood Hits	806
SwissProt Accessions	Q8QZX0	Gene names	Sbk1, Sbk
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SBK1 (EC 2.7.11.1) (SH3-binding kinase 1).

MLTK_HUMAN
θ value	2.98157e-11 (rank : 535)	NC score	0.763119 (rank : 537)
Query Neighborhood Hits	1959	Target Neighborhood Hits	911	Shared Neighborhood Hits	826
SwissProt Accessions	Q9NYL2, Q53SX1, Q580W8, Q59GY5, Q86YW8, Q9HCC4, Q9HCC5, Q9HDD2, Q9NYE9	Gene names	MLTK, ZAK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Cervical cancer suppressor gene 4 protein).

CDON_MOUSE
θ value	3.89403e-11 (rank : 536)	NC score	0.387859 (rank : 874)
Query Neighborhood Hits	1959	Target Neighborhood Hits	410	Shared Neighborhood Hits	308
SwissProt Accessions	Q32MD9, O88971	Gene names	Cdon, Cdo
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

JAK2_HUMAN
θ value	3.89403e-11 (rank : 537)	NC score	0.734763 (rank : 566)
Query Neighborhood Hits	1959	Target Neighborhood Hits	847	Shared Neighborhood Hits	811
SwissProt Accessions	O60674, O14636, O75297	Gene names	JAK2
Domain Architecture
Description	Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2).

MK14_HUMAN
θ value	3.89403e-11 (rank : 538)	NC score	0.810626 (rank : 394)
Query Neighborhood Hits	1959	Target Neighborhood Hits	838	Shared Neighborhood Hits	817
SwissProt Accessions	Q16539, O60776, Q13083, Q14084, Q8TDX0	Gene names	MAPK14, CSBP, CSBP1, CSBP2, MXI2
Domain Architecture
Description	Mitogen-activated protein kinase 14 (EC 2.7.11.24) (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Cytokine suppressive anti-inflammatory drug-binding protein) (CSAID-binding protein) (CSBP) (MAX-interacting protein 2) (MAP kinase MXI2) (SAPK2A).

PIM3_MOUSE
θ value	3.89403e-11 (rank : 539)	NC score	0.832928 (rank : 269)
Query Neighborhood Hits	1959	Target Neighborhood Hits	783	Shared Neighborhood Hits	769
SwissProt Accessions	P58750	Gene names	Pim3
Domain Architecture
Description	Serine/threonine-protein kinase Pim-3 (EC 2.7.11.1).

PTPRS_HUMAN
θ value	3.89403e-11 (rank : 540)	NC score	0.274332 (rank : 977)
Query Neighborhood Hits	1959	Target Neighborhood Hits	472	Shared Neighborhood Hits	316
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

STK39_HUMAN
θ value	3.89403e-11 (rank : 541)	NC score	0.828395 (rank : 296)
Query Neighborhood Hits	1959	Target Neighborhood Hits	882	Shared Neighborhood Hits	832
SwissProt Accessions	Q9UEW8, O14774, Q9UER4	Gene names	STK39, SPAK
Domain Architecture
Description	STE20/SPS1-related proline-alanine-rich protein kinase (EC 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39) (DCHT).

STK39_MOUSE
θ value	3.89403e-11 (rank : 542)	NC score	0.828908 (rank : 291)
Query Neighborhood Hits	1959	Target Neighborhood Hits	915	Shared Neighborhood Hits	841
SwissProt Accessions	Q9Z1W9, Q80W13	Gene names	Stk39, Spak
Domain Architecture
Description	STE20/SPS1-related proline-alanine-rich protein kinase (EC 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39).

BRAF1_HUMAN
θ value	5.08577e-11 (rank : 543)	NC score	0.767759 (rank : 526)
Query Neighborhood Hits	1959	Target Neighborhood Hits	883	Shared Neighborhood Hits	818
SwissProt Accessions	P15056, Q13878, Q9Y6T3	Gene names	BRAF, BRAF1, RAFB1
Domain Architecture
Description	B-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1).

ERN1_HUMAN
θ value	5.08577e-11 (rank : 544)	NC score	0.811086 (rank : 390)
Query Neighborhood Hits	1959	Target Neighborhood Hits	829	Shared Neighborhood Hits	805
SwissProt Accessions	O75460	Gene names	ERN1, IRE1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase/endoribonuclease IRE1 precursor (Inositol-requiring protein 1) (hIRE1p) (IRE1a) (Ire1-alpha) (Endoplasmic reticulum-to-nucleus signaling 1) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)].

FAK1_HUMAN
θ value	5.08577e-11 (rank : 545)	NC score	0.698051 (rank : 620)
Query Neighborhood Hits	1959	Target Neighborhood Hits	850	Shared Neighborhood Hits	806
SwissProt Accessions	Q05397, Q14291, Q9UD85	Gene names	PTK2, FAK, FAK1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK) (Protein- tyrosine kinase 2).

FAK1_MOUSE
θ value	5.08577e-11 (rank : 546)	NC score	0.697660 (rank : 621)
Query Neighborhood Hits	1959	Target Neighborhood Hits	850	Shared Neighborhood Hits	805
SwissProt Accessions	P34152, O08578	Gene names	Ptk2, Fadk, Fak, Fak1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK).

MK14_MOUSE
θ value	5.08577e-11 (rank : 547)	NC score	0.810815 (rank : 391)
Query Neighborhood Hits	1959	Target Neighborhood Hits	838	Shared Neighborhood Hits	817
SwissProt Accessions	P47811, O08666, Q3UZS3, Q8C289, Q9JLV8, Q9QZ80	Gene names	Mapk14, Crk1, Csbp1, Csbp2
Domain Architecture
Description	Mitogen-activated protein kinase 14 (EC 2.7.11.24) (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (CRK1).

RIPK5_HUMAN
θ value	5.08577e-11 (rank : 548)	NC score	0.790952 (rank : 470)
Query Neighborhood Hits	1959	Target Neighborhood Hits	864	Shared Neighborhood Hits	818
SwissProt Accessions	Q6XUX3, O75060, Q5RKT0, Q6IN87, Q6P997, Q86Y03, Q9P1S5	Gene names	RIPK5, KIAA0472, RIP5
Domain Architecture	No domain graphic available
Description	Receptor-interacting serine/threonine-protein kinase 5 (EC 2.7.11.1) (Dusty protein kinase) (Dusty PK) (RIP-homologous kinase).

RIPK5_MOUSE
θ value	5.08577e-11 (rank : 549)	NC score	0.790252 (rank : 471)
Query Neighborhood Hits	1959	Target Neighborhood Hits	874	Shared Neighborhood Hits	818
SwissProt Accessions	Q6XUX1, Q3ULK4, Q5EBN5, Q8C7D4, Q8C923, Q9CTP7	Gene names	Ripk5
Domain Architecture	No domain graphic available
Description	Receptor-interacting serine/threonine-protein kinase 5 (EC 2.7.11.1) (Dusty protein kinase) (Dusty PK).

JAK2_MOUSE
θ value	6.64225e-11 (rank : 550)	NC score	0.734041 (rank : 567)
Query Neighborhood Hits	1959	Target Neighborhood Hits	839	Shared Neighborhood Hits	806
SwissProt Accessions	Q62120, Q62124	Gene names	Jak2
Domain Architecture
Description	Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2).

MP2K5_HUMAN
θ value	6.64225e-11 (rank : 551)	NC score	0.819942 (rank : 346)
Query Neighborhood Hits	1959	Target Neighborhood Hits	837	Shared Neighborhood Hits	817
SwissProt Accessions	Q13163	Gene names	MAP2K5, MEK5, MKK5, PRKMK5
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 5 (EC 2.7.12.2) (MAP kinase kinase 5) (MAPKK 5) (MAPK/ERK kinase 5).

PIM1_MOUSE
θ value	6.64225e-11 (rank : 552)	NC score	0.834329 (rank : 262)
Query Neighborhood Hits	1959	Target Neighborhood Hits	787	Shared Neighborhood Hits	768
SwissProt Accessions	P06803	Gene names	Pim1, Pim-1
Domain Architecture	No domain graphic available
Description	Proto-oncogene serine/threonine-protein kinase Pim-1 (EC 2.7.11.1).

ERN1_MOUSE
θ value	8.67504e-11 (rank : 553)	NC score	0.810182 (rank : 397)
Query Neighborhood Hits	1959	Target Neighborhood Hits	823	Shared Neighborhood Hits	803
SwissProt Accessions	Q9EQY0, Q9D340	Gene names	Ern1, Ire1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase/endoribonuclease IRE1 precursor (Inositol-requiring protein 1) (IRE1a) (Ire1-alpha) (Endoplasmic reticulum-to-nucleus signaling 1) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)].

MK11_MOUSE
θ value	8.67504e-11 (rank : 554)	NC score	0.805756 (rank : 420)
Query Neighborhood Hits	1959	Target Neighborhood Hits	835	Shared Neighborhood Hits	816
SwissProt Accessions	Q9WUI1	Gene names	Mapk11, Prkm11
Domain Architecture
Description	Mitogen-activated protein kinase 11 (EC 2.7.11.24) (Mitogen-activated protein kinase p38 beta) (MAP kinase p38 beta) (p38B).

MLTK_MOUSE
θ value	8.67504e-11 (rank : 555)	NC score	0.763094 (rank : 538)
Query Neighborhood Hits	1959	Target Neighborhood Hits	874	Shared Neighborhood Hits	812
SwissProt Accessions	Q9ESL4, Q3V1X8, Q8BR73, Q9ESL3	Gene names	Mltk
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif kinase ZAK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK).

SRMS_HUMAN
θ value	8.67504e-11 (rank : 556)	NC score	0.683063 (rank : 654)
Query Neighborhood Hits	1959	Target Neighborhood Hits	946	Shared Neighborhood Hits	814
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).

WNK4_HUMAN
θ value	8.67504e-11 (rank : 557)	NC score	0.796143 (rank : 459)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1043	Shared Neighborhood Hits	866
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

CD2L1_HUMAN
θ value	1.133e-10 (rank : 558)	NC score	0.787077 (rank : 484)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1467	Shared Neighborhood Hits	895
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

MOS_MOUSE
θ value	1.133e-10 (rank : 559)	NC score	0.764944 (rank : 533)
Query Neighborhood Hits	1959	Target Neighborhood Hits	833	Shared Neighborhood Hits	813
SwissProt Accessions	P00536	Gene names	Mos
Domain Architecture	No domain graphic available
Description	Proto-oncogene serine/threonine-protein kinase mos (EC 2.7.11.1) (c- mos) (Oocyte maturation factor mos).

PIM2_HUMAN
θ value	1.133e-10 (rank : 560)	NC score	0.836784 (rank : 244)
Query Neighborhood Hits	1959	Target Neighborhood Hits	808	Shared Neighborhood Hits	792
SwissProt Accessions	Q9P1W9, Q99739	Gene names	PIM2
Domain Architecture
Description	Serine/threonine-protein kinase Pim-2 (EC 2.7.11.1) (Pim-2h).

WNK4_MOUSE
θ value	1.133e-10 (rank : 561)	NC score	0.796823 (rank : 458)
Query Neighborhood Hits	1959	Target Neighborhood Hits	961	Shared Neighborhood Hits	822
SwissProt Accessions	Q80UE6, Q4VAC1, Q80XB5, Q80XN2, Q8R0N0, Q8R340	Gene names	Wnk4, Prkwnk4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

CDK4_HUMAN
θ value	1.47974e-10 (rank : 562)	NC score	0.805238 (rank : 427)
Query Neighborhood Hits	1959	Target Neighborhood Hits	834	Shared Neighborhood Hits	815
SwissProt Accessions	P11802, O00576	Gene names	CDK4
Domain Architecture
Description	Cell division protein kinase 4 (EC 2.7.11.22) (Cyclin-dependent kinase 4) (PSK-J3).

LATS2_MOUSE
θ value	1.47974e-10 (rank : 563)	NC score	0.800199 (rank : 445)
Query Neighborhood Hits	1959	Target Neighborhood Hits	879	Shared Neighborhood Hits	826
SwissProt Accessions	Q7TSJ6, Q8CDJ4, Q9JMI3	Gene names	Lats2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein).

M3K8_MOUSE
θ value	1.47974e-10 (rank : 564)	NC score	0.832988 (rank : 268)
Query Neighborhood Hits	1959	Target Neighborhood Hits	815	Shared Neighborhood Hits	791
SwissProt Accessions	Q07174	Gene names	Map3k8, Cot
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 8 (EC 2.7.11.25) (COT proto-oncogene serine/threonine-protein kinase) (C-COT) (Cancer Osaka thyroid oncogene).

CD2L1_MOUSE
θ value	1.9326e-10 (rank : 565)	NC score	0.787465 (rank : 483)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1463	Shared Neighborhood Hits	892
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

DYRK4_HUMAN
θ value	1.9326e-10 (rank : 566)	NC score	0.777502 (rank : 506)
Query Neighborhood Hits	1959	Target Neighborhood Hits	750	Shared Neighborhood Hits	740
SwissProt Accessions	Q9NR20, Q8NEF2, Q92631	Gene names	DYRK4
Domain Architecture	No domain graphic available
Description	Dual specificity tyrosine-phosphorylation-regulated kinase 4 (EC 2.7.12.1).

CDK4_MOUSE
θ value	2.52405e-10 (rank : 567)	NC score	0.805590 (rank : 423)
Query Neighborhood Hits	1959	Target Neighborhood Hits	838	Shared Neighborhood Hits	815
SwissProt Accessions	P30285	Gene names	Cdk4, Crk3
Domain Architecture
Description	Cell division protein kinase 4 (EC 2.7.11.22) (Cyclin-dependent kinase 4) (PSK-J3) (CRK3).

JAK3_HUMAN
θ value	2.52405e-10 (rank : 568)	NC score	0.727177 (rank : 582)
Query Neighborhood Hits	1959	Target Neighborhood Hits	827	Shared Neighborhood Hits	802
SwissProt Accessions	P52333, Q13259, Q13260, Q13611, Q9Y6S2	Gene names	JAK3
Domain Architecture
Description	Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK).

LRRK2_HUMAN
θ value	2.52405e-10 (rank : 569)	NC score	0.701645 (rank : 613)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1382	Shared Neighborhood Hits	846
SwissProt Accessions	Q5S007, Q6ZS50, Q8NCX9	Gene names	LRRK2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin).

M3K8_HUMAN
θ value	2.52405e-10 (rank : 570)	NC score	0.832707 (rank : 271)
Query Neighborhood Hits	1959	Target Neighborhood Hits	807	Shared Neighborhood Hits	790
SwissProt Accessions	P41279, Q14275, Q9HC81	Gene names	MAP3K8, COT
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 8 (EC 2.7.11.25) (COT proto-oncogene serine/threonine-protein kinase) (C-COT) (Cancer Osaka thyroid oncogene).

IRAK4_MOUSE
θ value	3.29651e-10 (rank : 571)	NC score	0.778364 (rank : 504)
Query Neighborhood Hits	1959	Target Neighborhood Hits	820	Shared Neighborhood Hits	793
SwissProt Accessions	Q8R4K2, Q80WW1	Gene names	Irak4
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1) (IRAK-4).

LATS1_MOUSE
θ value	3.29651e-10 (rank : 572)	NC score	0.801781 (rank : 441)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1027	Shared Neighborhood Hits	872
SwissProt Accessions	Q8BYR2, Q9Z0W4	Gene names	Lats1, Warts
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase).

NTRI_HUMAN
θ value	3.29651e-10 (rank : 573)	NC score	0.358938 (rank : 900)
Query Neighborhood Hits	1959	Target Neighborhood Hits	344	Shared Neighborhood Hits	279
SwissProt Accessions	Q9P121, Q6UXJ3, Q86VJ9	Gene names	NT
Domain Architecture
Description	Neurotrimin precursor (hNT).

NTRI_MOUSE
θ value	3.29651e-10 (rank : 574)	NC score	0.359909 (rank : 899)
Query Neighborhood Hits	1959	Target Neighborhood Hits	342	Shared Neighborhood Hits	278
SwissProt Accessions	Q99PJ0	Gene names	Nt, Hnt
Domain Architecture
Description	Neurotrimin precursor.

RIPK1_HUMAN
θ value	3.29651e-10 (rank : 575)	NC score	0.776258 (rank : 508)
Query Neighborhood Hits	1959	Target Neighborhood Hits	891	Shared Neighborhood Hits	830
SwissProt Accessions	Q13546, Q13180	Gene names	RIPK1, RIP
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

VGFR2_MOUSE
θ value	3.29651e-10 (rank : 576)	NC score	0.710198 (rank : 605)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1089	Shared Neighborhood Hits	999
SwissProt Accessions	P35918	Gene names	Kdr, Flk-1, Flk1
Domain Architecture
Description	Vascular endothelial growth factor receptor 2 precursor (EC 2.7.10.1) (VEGFR-2) (Protein-tyrosine kinase receptor flk-1) (Fetal liver kinase 1) (Kinase NYK) (CD309 antigen).

SN_HUMAN
θ value	4.30538e-10 (rank : 577)	NC score	0.321909 (rank : 927)
Query Neighborhood Hits	1959	Target Neighborhood Hits	434	Shared Neighborhood Hits	279
SwissProt Accessions	Q9BZZ2, Q96DL4, Q9GZS5, Q9H1H6, Q9H1H7, Q9H7L7	Gene names	SN
Domain Architecture
Description	Sialoadhesin precursor (Sialic acid-binding Ig-like lectin-1) (Siglec- 1) (CD169 antigen).

LRRK2_MOUSE
θ value	5.62301e-10 (rank : 578)	NC score	0.685358 (rank : 648)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1359	Shared Neighborhood Hits	838
SwissProt Accessions	Q5S006, Q8BWG7, Q8BZJ6, Q8CI84, Q8K062	Gene names	Lrrk2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1).

RIPK1_MOUSE
θ value	5.62301e-10 (rank : 579)	NC score	0.769313 (rank : 522)
Query Neighborhood Hits	1959	Target Neighborhood Hits	874	Shared Neighborhood Hits	826
SwissProt Accessions	Q60855, Q3U0J3, Q8CD90	Gene names	Ripk1, Rinp, Rip
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

CD2L2_HUMAN
θ value	7.34386e-10 (rank : 580)	NC score	0.789288 (rank : 475)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1439	Shared Neighborhood Hits	897
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

CDK10_HUMAN
θ value	7.34386e-10 (rank : 581)	NC score	0.803340 (rank : 437)
Query Neighborhood Hits	1959	Target Neighborhood Hits	831	Shared Neighborhood Hits	816
SwissProt Accessions	Q15131, Q15130	Gene names	CDK10
Domain Architecture
Description	Cell division protein kinase 10 (EC 2.7.11.22) (Serine/threonine- protein kinase PISSLRE).

DYR1B_HUMAN
θ value	7.34386e-10 (rank : 582)	NC score	0.781972 (rank : 497)
Query Neighborhood Hits	1959	Target Neighborhood Hits	831	Shared Neighborhood Hits	791
SwissProt Accessions	Q9Y463, O75258, O75788, O75789	Gene names	DYRK1B, MIRK
Domain Architecture
Description	Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1) (Mirk protein kinase) (Minibrain-related kinase).

DYR1B_MOUSE
θ value	7.34386e-10 (rank : 583)	NC score	0.785588 (rank : 488)
Query Neighborhood Hits	1959	Target Neighborhood Hits	799	Shared Neighborhood Hits	779
SwissProt Accessions	Q9Z188	Gene names	Dyrk1b
Domain Architecture
Description	Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1).

FGFR1_MOUSE
θ value	7.34386e-10 (rank : 584)	NC score	0.751720 (rank : 548)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1068	Shared Neighborhood Hits	1010
SwissProt Accessions	P16092, Q01736, Q61562, Q80T10	Gene names	Fgfr1, Flg
Domain Architecture
Description	Basic fibroblast growth factor receptor 1 precursor (EC 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) (CD331 antigen).

MYBPH_MOUSE
θ value	7.34386e-10 (rank : 585)	NC score	0.327968 (rank : 924)
Query Neighborhood Hits	1959	Target Neighborhood Hits	290	Shared Neighborhood Hits	252
SwissProt Accessions	P70402	Gene names	Mybph
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

PRP4B_HUMAN
θ value	7.34386e-10 (rank : 586)	NC score	0.765489 (rank : 530)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1030	Shared Neighborhood Hits	818
SwissProt Accessions	Q13523, Q8TDP2, Q96QT7, Q9UEE6	Gene names	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (PRP4 kinase).

PRP4B_MOUSE
θ value	7.34386e-10 (rank : 587)	NC score	0.763483 (rank : 536)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1040	Shared Neighborhood Hits	816
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

BMX_MOUSE
θ value	9.59137e-10 (rank : 588)	NC score	0.689944 (rank : 634)
Query Neighborhood Hits	1959	Target Neighborhood Hits	912	Shared Neighborhood Hits	791
SwissProt Accessions	P97504	Gene names	Bmx
Domain Architecture	No domain graphic available
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein homolog).

DYR1A_HUMAN
θ value	9.59137e-10 (rank : 589)	NC score	0.771481 (rank : 519)
Query Neighborhood Hits	1959	Target Neighborhood Hits	764	Shared Neighborhood Hits	749
SwissProt Accessions	Q13627, O60769, Q92582, Q92810, Q9UNM5	Gene names	DYRK1A, DYRK, MNB, MNBH
Domain Architecture
Description	Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.1) (Protein kinase minibrain homolog) (MNBH) (HP86) (Dual specificity YAK1-related kinase).

DYR1A_MOUSE
θ value	9.59137e-10 (rank : 590)	NC score	0.771483 (rank : 518)
Query Neighborhood Hits	1959	Target Neighborhood Hits	762	Shared Neighborhood Hits	748
SwissProt Accessions	Q61214	Gene names	Dyrk1a, Dyrk
Domain Architecture
Description	Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.1) (Protein kinase minibrain homolog) (MNBH) (MP86) (Dual specificity YAK1-related kinase).

MK11_HUMAN
θ value	9.59137e-10 (rank : 591)	NC score	0.799350 (rank : 446)
Query Neighborhood Hits	1959	Target Neighborhood Hits	823	Shared Neighborhood Hits	810
SwissProt Accessions	Q15759, O00284, O15472, Q2XNF2	Gene names	MAPK11, PRKM11, SAPK2
Domain Architecture
Description	Mitogen-activated protein kinase 11 (EC 2.7.11.24) (Mitogen-activated protein kinase p38 beta) (MAP kinase p38 beta) (p38b) (p38-2) (Stress- activated protein kinase 2).

NTRK2_HUMAN
θ value	9.59137e-10 (rank : 592)	NC score	0.728052 (rank : 579)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1081	Shared Neighborhood Hits	963
SwissProt Accessions	Q16620, Q16675, Q8WXJ6	Gene names	NTRK2, TRKB
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB) (Trk-B).

NTRK2_MOUSE
θ value	9.59137e-10 (rank : 593)	NC score	0.728036 (rank : 580)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1088	Shared Neighborhood Hits	961
SwissProt Accessions	P15209, Q3TUF9, Q80WU0, Q91XJ9	Gene names	Ntrk2, Trkb
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B).

DYRK2_HUMAN
θ value	1.25267e-09 (rank : 594)	NC score	0.791454 (rank : 469)
Query Neighborhood Hits	1959	Target Neighborhood Hits	799	Shared Neighborhood Hits	779
SwissProt Accessions	Q92630	Gene names	DYRK2
Domain Architecture
Description	Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1).

E2AK2_HUMAN
θ value	1.25267e-09 (rank : 595)	NC score	0.828692 (rank : 293)
Query Neighborhood Hits	1959	Target Neighborhood Hits	856	Shared Neighborhood Hits	814
SwissProt Accessions	P19525	Gene names	EIF2AK2, PKR, PRKR
Domain Architecture
Description	Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Interferon-inducible RNA-dependent protein kinase) (Protein kinase RNA-activated) (PKR) (p68 kinase) (P1/eIF-2A protein kinase).

NEGR1_HUMAN
θ value	1.25267e-09 (rank : 596)	NC score	0.358912 (rank : 901)
Query Neighborhood Hits	1959	Target Neighborhood Hits	346	Shared Neighborhood Hits	269
SwissProt Accessions	Q7Z3B1, Q5VT21, Q6UY06, Q8NAQ3	Gene names	NEGR1
Domain Architecture	No domain graphic available
Description	Neuronal growth regulator 1 precursor.

FES_HUMAN
θ value	1.63604e-09 (rank : 597)	NC score	0.713643 (rank : 599)
Query Neighborhood Hits	1959	Target Neighborhood Hits	978	Shared Neighborhood Hits	802
SwissProt Accessions	P07332	Gene names	FES, FPS
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

LIMK1_HUMAN
θ value	1.63604e-09 (rank : 598)	NC score	0.748384 (rank : 552)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1005	Shared Neighborhood Hits	819
SwissProt Accessions	P53667, O15283, Q15820, Q15821, Q75MU3, Q9Y5Q1	Gene names	LIMK1, LIMK
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1).

MK15_HUMAN
θ value	1.63604e-09 (rank : 599)	NC score	0.818521 (rank : 355)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1038	Shared Neighborhood Hits	922
SwissProt Accessions	Q8TD08, Q2TCF9, Q8N362	Gene names	MAPK15, ERK8
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 8).

TESK1_MOUSE
θ value	1.63604e-09 (rank : 600)	NC score	0.782622 (rank : 496)
Query Neighborhood Hits	1959	Target Neighborhood Hits	862	Shared Neighborhood Hits	814
SwissProt Accessions	O70146, O70147	Gene names	Tesk1
Domain Architecture
Description	Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein kinase 1).

FGFR1_HUMAN
θ value	2.79066e-09 (rank : 601)	NC score	0.751608 (rank : 549)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1069	Shared Neighborhood Hits	1012
SwissProt Accessions	P11362, P17049, Q02063, Q02065, Q14306, Q14307, Q8N685	Gene names	FGFR1, FGFBR, FLG, FLT2
Domain Architecture
Description	Basic fibroblast growth factor receptor 1 precursor (EC 2.7.10.1) (FGFR-1) (bFGF-R) (Fms-like tyrosine kinase 2) (c-fgr) (CD331 antigen).

HCK_HUMAN
θ value	2.79066e-09 (rank : 602)	NC score	0.671105 (rank : 680)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1035	Shared Neighborhood Hits	827
SwissProt Accessions	P08631, Q5T7K1, Q5T7K2, Q96CC0, Q9H5Y5, Q9NUA4, Q9UMJ5	Gene names	HCK
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p59-HCK/p60-HCK) (Hemopoietic cell kinase).

MP2K6_HUMAN
θ value	2.79066e-09 (rank : 603)	NC score	0.805215 (rank : 429)
Query Neighborhood Hits	1959	Target Neighborhood Hits	830	Shared Neighborhood Hits	810
SwissProt Accessions	P52564	Gene names	MAP2K6, MEK6, MKK6, PRKMK6
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 6 (EC 2.7.12.2) (MAP kinase kinase 6) (MAPKK 6) (MAPK/ERK kinase 6) (SAPKK3).

BMX_HUMAN
θ value	3.64472e-09 (rank : 604)	NC score	0.690668 (rank : 632)
Query Neighborhood Hits	1959	Target Neighborhood Hits	942	Shared Neighborhood Hits	803
SwissProt Accessions	P51813, O60564, Q12871	Gene names	BMX
Domain Architecture
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38).

MYBPH_HUMAN
θ value	3.64472e-09 (rank : 605)	NC score	0.329098 (rank : 923)
Query Neighborhood Hits	1959	Target Neighborhood Hits	256	Shared Neighborhood Hits	238
SwissProt Accessions	Q13203, Q16886, Q86YC5	Gene names	MYBPH
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

NEGR1_MOUSE
θ value	3.64472e-09 (rank : 606)	NC score	0.358445 (rank : 902)
Query Neighborhood Hits	1959	Target Neighborhood Hits	349	Shared Neighborhood Hits	270
SwissProt Accessions	Q80Z24, Q3UHQ8, Q80T70	Gene names	Negr1, Kiaa3001, Ntra
Domain Architecture	No domain graphic available
Description	Neuronal growth regulator 1 precursor (Kilon protein) (Kindred of IgLON) (Neurotractin).

M3KL4_HUMAN
θ value	4.76016e-09 (rank : 607)	NC score	0.753731 (rank : 546)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1087	Shared Neighborhood Hits	832
SwissProt Accessions	Q5TCX8, Q5TCX7, Q5TCX9, Q8WWN1, Q8WWN2, Q96JM1	Gene names	MLK4, KIAA1804
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase 4).

MAMC1_MOUSE
θ value	4.76016e-09 (rank : 608)	NC score	0.353541 (rank : 907)
Query Neighborhood Hits	1959	Target Neighborhood Hits	357	Shared Neighborhood Hits	270
SwissProt Accessions	P60755	Gene names	Mamdc1, Mdga2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

MK09_HUMAN
θ value	4.76016e-09 (rank : 609)	NC score	0.804539 (rank : 433)
Query Neighborhood Hits	1959	Target Neighborhood Hits	842	Shared Neighborhood Hits	822
SwissProt Accessions	P45984, Q15708, Q15710, Q15711, Q8N5C5	Gene names	MAPK9, JNK2, PRKM9
Domain Architecture
Description	Mitogen-activated protein kinase 9 (EC 2.7.11.24) (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2) (JNK-55).

MK10_MOUSE
θ value	4.76016e-09 (rank : 610)	NC score	0.797341 (rank : 456)
Query Neighborhood Hits	1959	Target Neighborhood Hits	849	Shared Neighborhood Hits	819
SwissProt Accessions	Q61831, Q9R0U6	Gene names	Mapk10, Jnk3, Prkm10, Serk2
Domain Architecture
Description	Mitogen-activated protein kinase 10 (EC 2.7.11.24) (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3) (MAP kinase p49 3F12).

TXK_HUMAN
θ value	4.76016e-09 (rank : 611)	NC score	0.693160 (rank : 630)
Query Neighborhood Hits	1959	Target Neighborhood Hits	971	Shared Neighborhood Hits	809
SwissProt Accessions	P42681, Q14220	Gene names	TXK
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2).

TXK_MOUSE
θ value	4.76016e-09 (rank : 612)	NC score	0.681384 (rank : 655)
Query Neighborhood Hits	1959	Target Neighborhood Hits	980	Shared Neighborhood Hits	803
SwissProt Accessions	P42682	Gene names	Txk, Rlk
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18) (Resting lymphocyte kinase).

GAK_HUMAN
θ value	6.21693e-09 (rank : 613)	NC score	0.788035 (rank : 480)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1028	Shared Neighborhood Hits	883
SwissProt Accessions	O14976, Q9BVY6	Gene names	GAK
Domain Architecture
Description	Cyclin G-associated kinase (EC 2.7.11.1).

HIPK2_HUMAN
θ value	6.21693e-09 (rank : 614)	NC score	0.773115 (rank : 515)
Query Neighborhood Hits	1959	Target Neighborhood Hits	845	Shared Neighborhood Hits	796
SwissProt Accessions	Q9H2X6, Q75MR7, Q8WWI4, Q9H2Y1	Gene names	HIPK2
Domain Architecture
Description	Homeodomain-interacting protein kinase 2 (EC 2.7.11.1) (hHIPk2).

HIPK2_MOUSE
θ value	6.21693e-09 (rank : 615)	NC score	0.772496 (rank : 516)
Query Neighborhood Hits	1959	Target Neighborhood Hits	871	Shared Neighborhood Hits	803
SwissProt Accessions	Q9QZR5, O88905, Q99P45, Q99P46, Q9D2E6, Q9D474, Q9EQL2, Q9QZR4	Gene names	Hipk2, Nbak1, Stank
Domain Architecture
Description	Homeodomain-interacting protein kinase 2 (EC 2.7.11.1) (Nuclear body- associated kinase 1) (Sialophorin tail-associated nuclear serine/threonine-protein kinase).

MAMC1_HUMAN
θ value	6.21693e-09 (rank : 616)	NC score	0.354241 (rank : 906)
Query Neighborhood Hits	1959	Target Neighborhood Hits	357	Shared Neighborhood Hits	271
SwissProt Accessions	Q7Z553	Gene names	MAMDC1, MDGA2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

CD22_HUMAN
θ value	8.11959e-09 (rank : 617)	NC score	0.311952 (rank : 936)
Query Neighborhood Hits	1959	Target Neighborhood Hits	365	Shared Neighborhood Hits	246
SwissProt Accessions	P20273, O95699, O95701, O95702, O95703, Q01665, Q92872, Q92873, Q9UQA6, Q9UQA7, Q9UQA8, Q9UQA9, Q9UQB0, Q9Y2A6	Gene names	CD22
Domain Architecture
Description	B-cell receptor CD22 precursor (Leu-14) (B-lymphocyte cell adhesion molecule) (BL-CAM) (Siglec-2).

HIPK1_HUMAN
θ value	8.11959e-09 (rank : 618)	NC score	0.774018 (rank : 513)
Query Neighborhood Hits	1959	Target Neighborhood Hits	843	Shared Neighborhood Hits	794
SwissProt Accessions	Q86Z02, O75125, Q8IYD7, Q8NDN5, Q8NEB6, Q8TBZ1	Gene names	HIPK1, KIAA0630
Domain Architecture
Description	Homeodomain-interacting protein kinase 1 (EC 2.7.11.1).

HIPK1_MOUSE
θ value	8.11959e-09 (rank : 619)	NC score	0.773710 (rank : 514)
Query Neighborhood Hits	1959	Target Neighborhood Hits	838	Shared Neighborhood Hits	790
SwissProt Accessions	O88904, Q80TV5, Q9QUQ8, Q9QZR3, Q9WVN7	Gene names	Hipk1, Kiaa0630, Myak, Nbak2
Domain Architecture
Description	Homeodomain-interacting protein kinase 1 (EC 2.7.11.1) (Protein kinase Myak) (Nuclear body-associated kinase 2).

KIRR2_HUMAN
θ value	8.11959e-09 (rank : 620)	NC score	0.318533 (rank : 928)
Query Neighborhood Hits	1959	Target Neighborhood Hits	321	Shared Neighborhood Hits	238
SwissProt Accessions	Q6UWL6, Q6P1R1, Q7Z5P1, Q7Z5P2, Q96IQ8, Q9H0T1	Gene names	KIRREL2, NEPH3
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2) (Nephrin-like protein 3).

LYN_MOUSE
θ value	8.11959e-09 (rank : 621)	NC score	0.685491 (rank : 647)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1023	Shared Neighborhood Hits	834
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

RYK_MOUSE
θ value	8.11959e-09 (rank : 622)	NC score	0.551917 (rank : 805)
Query Neighborhood Hits	1959	Target Neighborhood Hits	715	Shared Neighborhood Hits	692
SwissProt Accessions	Q01887, Q61890	Gene names	Ryk, Mrk
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1) (Kinase VIK) (NYK- R) (Met-related kinase).

GAK_MOUSE
θ value	1.06045e-08 (rank : 623)	NC score	0.784248 (rank : 493)
Query Neighborhood Hits	1959	Target Neighborhood Hits	964	Shared Neighborhood Hits	837
SwissProt Accessions	Q99KY4, Q6P1I8, Q6P9S5, Q8BM74, Q8K0Q4	Gene names	Gak
Domain Architecture	No domain graphic available
Description	Cyclin G-associated kinase (EC 2.7.11.1).

LATS2_HUMAN
θ value	1.06045e-08 (rank : 624)	NC score	0.798982 (rank : 450)
Query Neighborhood Hits	1959	Target Neighborhood Hits	884	Shared Neighborhood Hits	832
SwissProt Accessions	Q9NRM7, Q9P2X1	Gene names	LATS2, KPM
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein) (Warts-like kinase).

MK10_HUMAN
θ value	1.06045e-08 (rank : 625)	NC score	0.797737 (rank : 455)
Query Neighborhood Hits	1959	Target Neighborhood Hits	836	Shared Neighborhood Hits	815
SwissProt Accessions	P53779, Q15707	Gene names	MAPK10, JNK3, JNK3A, PRKM10
Domain Architecture
Description	Mitogen-activated protein kinase 10 (EC 2.7.11.24) (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3) (MAP kinase p49 3F12).

CLK2_HUMAN
θ value	1.38499e-08 (rank : 626)	NC score	0.752000 (rank : 547)
Query Neighborhood Hits	1959	Target Neighborhood Hits	752	Shared Neighborhood Hits	736
SwissProt Accessions	P49760, Q96CQ0	Gene names	CLK2
Domain Architecture
Description	Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2).

E2AK3_MOUSE
θ value	1.38499e-08 (rank : 627)	NC score	0.802538 (rank : 439)
Query Neighborhood Hits	1959	Target Neighborhood Hits	851	Shared Neighborhood Hits	821
SwissProt Accessions	Q9Z2B5, Q9CTK8, Q9CWT5	Gene names	Eif2ak3, Pek, Perk
Domain Architecture
Description	Eukaryotic translation initiation factor 2-alpha kinase 3 precursor (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase).

FGFR2_HUMAN
θ value	1.38499e-08 (rank : 628)	NC score	0.748333 (rank : 553)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1062	Shared Neighborhood Hits	996
SwissProt Accessions	P21802, P18443, Q01742, Q12922, Q14300, Q14301, Q14302, Q14303, Q14304, Q14305, Q14672, Q14718, Q14719, Q86YI4, Q96KL9, Q96KM0, Q96KM1, Q96KM2, Q9NZU2, Q9NZU3, Q9UD01, Q9UD02, Q9UIH3, Q9UIH4, Q9UIH5, Q9UIH6, Q9UIH7, Q9UIH8, Q9UM87, Q9UMC6, Q9UNS7, Q9UQH7, Q9UQH8, Q9UQH9, Q9UQI0	Gene names	FGFR2, BEK, KSAM
Domain Architecture
Description	Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor 2) (CD332 antigen).

MATK_MOUSE
θ value	1.38499e-08 (rank : 629)	NC score	0.687979 (rank : 642)
Query Neighborhood Hits	1959	Target Neighborhood Hits	952	Shared Neighborhood Hits	820
SwissProt Accessions	P41242, Q6LE90	Gene names	Matk, Ctk, Ntk
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK).

MK09_MOUSE
θ value	1.38499e-08 (rank : 630)	NC score	0.800533 (rank : 444)
Query Neighborhood Hits	1959	Target Neighborhood Hits	843	Shared Neighborhood Hits	821
SwissProt Accessions	Q9WTU6, Q8C097, Q8VDD2, Q9WTU4, Q9WTU5	Gene names	Mapk9, Jnk2, Prkm9
Domain Architecture
Description	Mitogen-activated protein kinase 9 (EC 2.7.11.24) (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2).

MP2K6_MOUSE
θ value	1.38499e-08 (rank : 631)	NC score	0.806036 (rank : 417)
Query Neighborhood Hits	1959	Target Neighborhood Hits	830	Shared Neighborhood Hits	811
SwissProt Accessions	P70236	Gene names	Map2k6, Prkmk6, Sapkk3
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 6 (EC 2.7.12.2) (MAP kinase kinase 6) (MAPKK 6) (MAPK/ERK kinase 6) (SAPKK3).

ROR2_MOUSE
θ value	1.38499e-08 (rank : 632)	NC score	0.676685 (rank : 665)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1000	Shared Neighborhood Hits	930
SwissProt Accessions	Q9Z138	Gene names	Ror2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2) (mROR2).

SN_MOUSE
θ value	1.38499e-08 (rank : 633)	NC score	0.324800 (rank : 925)
Query Neighborhood Hits	1959	Target Neighborhood Hits	416	Shared Neighborhood Hits	277
SwissProt Accessions	Q62230, O55216, Q62228, Q62229	Gene names	Sn, Sa
Domain Architecture
Description	Sialoadhesin precursor (Sialic acid-binding Ig-like lectin-1) (Siglec- 1) (Sheep erythrocyte receptor) (SER) (CD169 antigen).

WEE1_MOUSE
θ value	1.38499e-08 (rank : 634)	NC score	0.787748 (rank : 481)
Query Neighborhood Hits	1959	Target Neighborhood Hits	794	Shared Neighborhood Hits	762
SwissProt Accessions	P47810, Q9EPL7	Gene names	Wee1
Domain Architecture
Description	Wee1-like protein kinase (EC 2.7.10.2) (Wee1A kinase).

LCK_HUMAN
θ value	1.80886e-08 (rank : 635)	NC score	0.672331 (rank : 675)
Query Neighborhood Hits	1959	Target Neighborhood Hits	987	Shared Neighborhood Hits	821
SwissProt Accessions	P06239, P07100, Q12850, Q13152, Q5TDH8, Q5TDH9, Q96DW4, Q9NYT8	Gene names	LCK
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell- specific protein-tyrosine kinase).

LYN_HUMAN
θ value	1.80886e-08 (rank : 636)	NC score	0.684328 (rank : 651)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1022	Shared Neighborhood Hits	834
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

MOS_HUMAN
θ value	1.80886e-08 (rank : 637)	NC score	0.764380 (rank : 535)
Query Neighborhood Hits	1959	Target Neighborhood Hits	829	Shared Neighborhood Hits	812
SwissProt Accessions	P00540	Gene names	MOS
Domain Architecture
Description	Proto-oncogene serine/threonine-protein kinase mos (EC 2.7.11.1) (c- mos) (Oocyte maturation factor mos).

PTK6_MOUSE
θ value	1.80886e-08 (rank : 638)	NC score	0.707772 (rank : 609)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1026	Shared Neighborhood Hits	821
SwissProt Accessions	Q64434	Gene names	Ptk6, Sik
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related intestinal kinase).

SRRM2_HUMAN
θ value	1.80886e-08 (rank : 639)	NC score	0.118797 (rank : 1100)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1296	Shared Neighborhood Hits	457
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

STK40_HUMAN
θ value	1.80886e-08 (rank : 640)	NC score	0.810742 (rank : 392)
Query Neighborhood Hits	1959	Target Neighborhood Hits	751	Shared Neighborhood Hits	734
SwissProt Accessions	Q8N2I9, Q5VTK8, Q5VTK9, Q6ZMN1, Q8N2J8, Q8N3I6, Q96HN6, Q96I44, Q9BSA3, Q9H7H6	Gene names	STK40, SHIK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 40 (EC 2.7.11.1) (SINK-homologous serine/threonine-protein kinase).

STK40_MOUSE
θ value	1.80886e-08 (rank : 641)	NC score	0.810611 (rank : 395)
Query Neighborhood Hits	1959	Target Neighborhood Hits	751	Shared Neighborhood Hits	734
SwissProt Accessions	Q7TNL3, Q3U3G3, Q811D6, Q8BKT1, Q9D7K3	Gene names	Stk40, Lyk4
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 40 (EC 2.7.11.1) (Serine/threonine- protein kinase lyk4).

CI094_HUMAN
θ value	2.36244e-08 (rank : 642)	NC score	0.280328 (rank : 966)
Query Neighborhood Hits	1959	Target Neighborhood Hits	310	Shared Neighborhood Hits	232
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

JAK1_HUMAN
θ value	2.36244e-08 (rank : 643)	NC score	0.716975 (rank : 594)
Query Neighborhood Hits	1959	Target Neighborhood Hits	858	Shared Neighborhood Hits	811
SwissProt Accessions	P23458	Gene names	JAK1, JAK1A
Domain Architecture
Description	Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1).

LIMK1_MOUSE
θ value	2.36244e-08 (rank : 644)	NC score	0.747489 (rank : 555)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1008	Shared Neighborhood Hits	817
SwissProt Accessions	P53668	Gene names	Limk1, Limk
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (KIZ-1).

PDK1L_HUMAN
θ value	2.36244e-08 (rank : 645)	NC score	0.832525 (rank : 272)
Query Neighborhood Hits	1959	Target Neighborhood Hits	821	Shared Neighborhood Hits	801
SwissProt Accessions	Q8N165, Q5T2I0, Q8NDB3	Gene names	PDIK1L, CLIK1L
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PDIK1L (EC 2.7.11.1) (PDLIM1- interacting kinase 1-like).

PDK1L_MOUSE
θ value	2.36244e-08 (rank : 646)	NC score	0.832404 (rank : 273)
Query Neighborhood Hits	1959	Target Neighborhood Hits	821	Shared Neighborhood Hits	802
SwissProt Accessions	Q8QZR7, Q3URF0, Q8BKB3	Gene names	Pdik1l
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PDIK1L (EC 2.7.11.1) (PDLIM1- interacting kinase 1-like).

ROR2_HUMAN
θ value	2.36244e-08 (rank : 647)	NC score	0.696924 (rank : 624)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1014	Shared Neighborhood Hits	949
SwissProt Accessions	Q01974, Q59GF5, Q5SPI5, Q9HAY7, Q9HB61	Gene names	ROR2, NTRKR2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2).

TRIB2_HUMAN
θ value	2.36244e-08 (rank : 648)	NC score	0.770981 (rank : 520)
Query Neighborhood Hits	1959	Target Neighborhood Hits	657	Shared Neighborhood Hits	649
SwissProt Accessions	Q92519	Gene names	TRIB2, TRB2
Domain Architecture	No domain graphic available
Description	Tribbles homolog 2 (TRB-2).

TRIB2_MOUSE
θ value	2.36244e-08 (rank : 649)	NC score	0.770443 (rank : 521)
Query Neighborhood Hits	1959	Target Neighborhood Hits	653	Shared Neighborhood Hits	645
SwissProt Accessions	Q8K4K3, Q8K017, Q8R2V8	Gene names	Trib2
Domain Architecture	No domain graphic available
Description	Tribbles homolog 2 (TRB-2).

TYK2_HUMAN
θ value	2.36244e-08 (rank : 650)	NC score	0.727412 (rank : 581)
Query Neighborhood Hits	1959	Target Neighborhood Hits	841	Shared Neighborhood Hits	813
SwissProt Accessions	P29597, Q6QB10, Q96CH0	Gene names	TYK2
Domain Architecture
Description	Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2).

CSK21_HUMAN
θ value	3.08544e-08 (rank : 651)	NC score	0.804781 (rank : 432)
Query Neighborhood Hits	1959	Target Neighborhood Hits	772	Shared Neighborhood Hits	763
SwissProt Accessions	P68400, P19138, P20426, Q14013	Gene names	CSNK2A1, CK2A1
Domain Architecture	No domain graphic available
Description	Casein kinase II subunit alpha (EC 2.7.11.1) (CK II).

FES_MOUSE
θ value	3.08544e-08 (rank : 652)	NC score	0.714657 (rank : 597)
Query Neighborhood Hits	1959	Target Neighborhood Hits	980	Shared Neighborhood Hits	812
SwissProt Accessions	P16879, Q62122	Gene names	Fes, Fps
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

LCK_MOUSE
θ value	3.08544e-08 (rank : 653)	NC score	0.676817 (rank : 663)
Query Neighborhood Hits	1959	Target Neighborhood Hits	981	Shared Neighborhood Hits	819
SwissProt Accessions	P06240, Q61794, Q61795, Q62320, Q91X65	Gene names	Lck, Lsk-t
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK).

MK15_MOUSE
θ value	3.08544e-08 (rank : 654)	NC score	0.814666 (rank : 372)
Query Neighborhood Hits	1959	Target Neighborhood Hits	843	Shared Neighborhood Hits	819
SwissProt Accessions	Q80Y86	Gene names	Mapk15, Erk7
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 7).

MP2K7_HUMAN
θ value	3.08544e-08 (rank : 655)	NC score	0.818282 (rank : 357)
Query Neighborhood Hits	1959	Target Neighborhood Hits	833	Shared Neighborhood Hits	806
SwissProt Accessions	O14733, O14648, O14816, O60452, O60453	Gene names	MAP2K7, JNKK2, MKK7, PRKMK7
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 7 (EC 2.7.12.2) (MAP kinase kinase 7) (MAPKK 7) (MAPK/ERK kinase 7) (JNK-activating kinase 2) (c-Jun N-terminal kinase kinase 2) (JNK kinase 2) (JNKK 2).

TRIB3_HUMAN
θ value	3.08544e-08 (rank : 656)	NC score	0.710691 (rank : 604)
Query Neighborhood Hits	1959	Target Neighborhood Hits	519	Shared Neighborhood Hits	513
SwissProt Accessions	Q96RU7, Q53GU4, Q53ZW7, Q6I9Y9, Q8TAI6, Q9H5M8, Q9NUD2	Gene names	TRIB3, C20orf97, NIPK, SKIP3, TRB3
Domain Architecture
Description	Tribbles homolog 3 (TRB-3) (Neuronal cell death-inducible putative kinase) (p65-interacting inhibitor of NF-kappaB) (SINK).

FRK_HUMAN
θ value	4.0297e-08 (rank : 657)	NC score	0.684667 (rank : 650)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1058	Shared Neighborhood Hits	828
SwissProt Accessions	P42685, Q13128	Gene names	FRK
Domain Architecture
Description	Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear tyrosine protein kinase RAK).

GRK7_HUMAN
θ value	4.0297e-08 (rank : 658)	NC score	0.828540 (rank : 295)
Query Neighborhood Hits	1959	Target Neighborhood Hits	820	Shared Neighborhood Hits	809
SwissProt Accessions	Q8WTQ7	Gene names	GRK7, GPRK7
Domain Architecture
Description	G protein-coupled receptor kinase 7 precursor (EC 2.7.11.16) (G protein-coupled receptor kinase GRK7).

HIPK3_HUMAN
θ value	4.0297e-08 (rank : 659)	NC score	0.774132 (rank : 512)
Query Neighborhood Hits	1959	Target Neighborhood Hits	867	Shared Neighborhood Hits	807
SwissProt Accessions	Q9H422, O14632, Q2PBG4, Q2PBG5, Q92632, Q9HAS2	Gene names	HIPK3, DYRK6, FIST3, PKY
Domain Architecture	No domain graphic available
Description	Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Homolog of protein kinase YAK1) (Fas-interacting serine/threonine-protein kinase) (FIST) (Androgen receptor-interacting nuclear protein kinase) (ANPK).

HIPK3_MOUSE
θ value	4.0297e-08 (rank : 660)	NC score	0.775978 (rank : 509)
Query Neighborhood Hits	1959	Target Neighborhood Hits	857	Shared Neighborhood Hits	802
SwissProt Accessions	Q9ERH7, O88906, Q9QZR2	Gene names	Hipk3, Fist3
Domain Architecture	No domain graphic available
Description	Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Fas- interacting serine/threonine-protein kinase) (FIST) (Nuclear body- associated kinase 3) (Nbak3) (Androgen receptor-interacting nuclear protein kinase) (ANPK).

EPHB3_HUMAN
θ value	5.26297e-08 (rank : 661)	NC score	0.656709 (rank : 719)
Query Neighborhood Hits	1959	Target Neighborhood Hits	996	Shared Neighborhood Hits	876
SwissProt Accessions	P54753, Q7Z740	Gene names	EPHB3, ETK2, HEK2
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2).

EPHB3_MOUSE
θ value	5.26297e-08 (rank : 662)	NC score	0.655547 (rank : 722)
Query Neighborhood Hits	1959	Target Neighborhood Hits	996	Shared Neighborhood Hits	873
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

RYK_HUMAN
θ value	5.26297e-08 (rank : 663)	NC score	0.537799 (rank : 809)
Query Neighborhood Hits	1959	Target Neighborhood Hits	701	Shared Neighborhood Hits	681
SwissProt Accessions	P34925, Q04696	Gene names	RYK, JTK5A
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1).

TYK2_MOUSE
θ value	5.26297e-08 (rank : 664)	NC score	0.723047 (rank : 587)
Query Neighborhood Hits	1959	Target Neighborhood Hits	850	Shared Neighborhood Hits	816
SwissProt Accessions	Q9R117, O88431, Q8VE41	Gene names	Tyk2
Domain Architecture
Description	Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2).

CSK_MOUSE
θ value	6.87365e-08 (rank : 665)	NC score	0.695445 (rank : 626)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1009	Shared Neighborhood Hits	820
SwissProt Accessions	P41241, Q03143	Gene names	Csk
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase MPK-2) (p50CSK).

FER_HUMAN
θ value	6.87365e-08 (rank : 666)	NC score	0.695152 (rank : 627)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1278	Shared Neighborhood Hits	811
SwissProt Accessions	P16591	Gene names	FER, TYK3
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2) (p94-FER) (c- FER).

FGFR2_MOUSE
θ value	6.87365e-08 (rank : 667)	NC score	0.744960 (rank : 557)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1062	Shared Neighborhood Hits	994
SwissProt Accessions	P21803, O55141, Q00389, Q61342	Gene names	Fgfr2, Bek, Ect1
Domain Architecture
Description	Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor) (CD332 antigen).

MASTL_MOUSE
θ value	6.87365e-08 (rank : 668)	NC score	0.821362 (rank : 340)
Query Neighborhood Hits	1959	Target Neighborhood Hits	862	Shared Neighborhood Hits	823
SwissProt Accessions	Q8C0P0, Q5RJW0, Q6NXX9, Q8BVF3, Q9CZH9, Q9D9V0	Gene names	Mastl
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase-like (EC 2.7.11.1).

MATK_HUMAN
θ value	6.87365e-08 (rank : 669)	NC score	0.683725 (rank : 653)
Query Neighborhood Hits	1959	Target Neighborhood Hits	954	Shared Neighborhood Hits	817
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

TESK1_HUMAN
θ value	6.87365e-08 (rank : 670)	NC score	0.780905 (rank : 500)
Query Neighborhood Hits	1959	Target Neighborhood Hits	864	Shared Neighborhood Hits	811
SwissProt Accessions	Q15569	Gene names	TESK1
Domain Architecture
Description	Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein kinase 1).

VGFR3_MOUSE
θ value	6.87365e-08 (rank : 671)	NC score	0.693275 (rank : 629)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1056	Shared Neighborhood Hits	981
SwissProt Accessions	P35917	Gene names	Flt4, Flt-4
Domain Architecture
Description	Vascular endothelial growth factor receptor 3 precursor (EC 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4).

CLK2_MOUSE
θ value	8.97725e-08 (rank : 672)	NC score	0.739897 (rank : 562)
Query Neighborhood Hits	1959	Target Neighborhood Hits	743	Shared Neighborhood Hits	730
SwissProt Accessions	O35491	Gene names	Clk2
Domain Architecture
Description	Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2).

IRAK4_HUMAN
θ value	8.97725e-08 (rank : 673)	NC score	0.772417 (rank : 517)
Query Neighborhood Hits	1959	Target Neighborhood Hits	816	Shared Neighborhood Hits	794
SwissProt Accessions	Q9NWZ3, Q8TDF7, Q9Y589	Gene names	IRAK4
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1) (IRAK-4) (NY- REN-64 antigen).

ITK_MOUSE
θ value	8.97725e-08 (rank : 674)	NC score	0.688945 (rank : 637)
Query Neighborhood Hits	1959	Target Neighborhood Hits	985	Shared Neighborhood Hits	815
SwissProt Accessions	Q03526	Gene names	Itk, Emt, Tlk, Tsk
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK).

MASTL_HUMAN
θ value	8.97725e-08 (rank : 675)	NC score	0.821750 (rank : 339)
Query Neighborhood Hits	1959	Target Neighborhood Hits	894	Shared Neighborhood Hits	828
SwissProt Accessions	Q96GX5, Q5T8D5, Q5T8D7, Q8NCD6, Q96SJ5	Gene names	MASTL, THC2
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase-like (EC 2.7.11.1).

CSK21_MOUSE
θ value	1.17247e-07 (rank : 676)	NC score	0.805000 (rank : 431)
Query Neighborhood Hits	1959	Target Neighborhood Hits	770	Shared Neighborhood Hits	763
SwissProt Accessions	Q60737	Gene names	Csnk2a1, Ckiia
Domain Architecture
Description	Casein kinase II subunit alpha (EC 2.7.11.1) (CK II).

HCK_MOUSE
θ value	1.17247e-07 (rank : 677)	NC score	0.666056 (rank : 690)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1029	Shared Neighborhood Hits	823
SwissProt Accessions	P08103	Gene names	Hck
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK).

MP2K3_HUMAN
θ value	1.17247e-07 (rank : 678)	NC score	0.807733 (rank : 409)
Query Neighborhood Hits	1959	Target Neighborhood Hits	825	Shared Neighborhood Hits	810
SwissProt Accessions	P46734, Q99441, Q9UE71, Q9UE72	Gene names	MAP2K3, MEK3, MKK3, PRKMK3
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 3 (EC 2.7.12.2) (MAP kinase kinase 3) (MAPKK 3) (MAPK/ERK kinase 3).

MP2K4_HUMAN
θ value	1.17247e-07 (rank : 679)	NC score	0.811380 (rank : 387)
Query Neighborhood Hits	1959	Target Neighborhood Hits	832	Shared Neighborhood Hits	811
SwissProt Accessions	P45985, Q5U0B8	Gene names	MAP2K4, JNKK1, MKK4, PRKMK4, SERK1
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 4 (EC 2.7.12.2) (MAP kinase kinase 4) (JNK-activating kinase 1) (c-Jun N-terminal kinase kinase 1) (JNKK) (SAPK/ERK kinase 1) (SEK1).

VGFR3_HUMAN
θ value	1.17247e-07 (rank : 680)	NC score	0.689658 (rank : 635)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1037	Shared Neighborhood Hits	974
SwissProt Accessions	P35916	Gene names	FLT4
Domain Architecture
Description	Vascular endothelial growth factor receptor 3 precursor (EC 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4).

FGFR3_HUMAN
θ value	1.53129e-07 (rank : 681)	NC score	0.741399 (rank : 561)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1042	Shared Neighborhood Hits	996
SwissProt Accessions	P22607, Q14308, Q16294, Q16608	Gene names	FGFR3, JTK4
Domain Architecture
Description	Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1) (FGFR-3) (CD333 antigen).

LRRK1_MOUSE
θ value	1.53129e-07 (rank : 682)	NC score	0.713765 (rank : 598)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1267	Shared Neighborhood Hits	838
SwissProt Accessions	Q3UHC2, Q3U476, Q66JQ4, Q6GQR9, Q6NZF5, Q6ZPI4, Q8BKP3, Q8BU93, Q8BUY0, Q8BVV2, Q8R085	Gene names	Lrrk1, Kiaa1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

MK08_HUMAN
θ value	1.53129e-07 (rank : 683)	NC score	0.798025 (rank : 453)
Query Neighborhood Hits	1959	Target Neighborhood Hits	834	Shared Neighborhood Hits	814
SwissProt Accessions	P45983, Q15709, Q15712, Q15713	Gene names	MAPK8, JNK1, PRKM8
Domain Architecture
Description	Mitogen-activated protein kinase 8 (EC 2.7.11.24) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1) (JNK-46).

MK08_MOUSE
θ value	1.53129e-07 (rank : 684)	NC score	0.798673 (rank : 452)
Query Neighborhood Hits	1959	Target Neighborhood Hits	834	Shared Neighborhood Hits	814
SwissProt Accessions	Q91Y86	Gene names	Mapk8, Jnk1, Prkm8
Domain Architecture
Description	Mitogen-activated protein kinase 8 (EC 2.7.11.24) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1).

MP2K4_MOUSE
θ value	1.53129e-07 (rank : 685)	NC score	0.811336 (rank : 388)
Query Neighborhood Hits	1959	Target Neighborhood Hits	833	Shared Neighborhood Hits	811
SwissProt Accessions	P47809	Gene names	Map2k4, Jnkk1, Prkmk4, Sek1, Serk1
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 4 (EC 2.7.12.2) (MAP kinase kinase 4) (MAPKK 4) (MAPK/ERK kinase 4) (JNK-activating kinase 1) (C-JUN N-terminal kinase kinase 1) (JNK kinase 1) (JNKK 1) (SAPK/ERK kinase 1) (SEK1).

TRIB1_HUMAN
θ value	1.53129e-07 (rank : 686)	NC score	0.743451 (rank : 558)
Query Neighborhood Hits	1959	Target Neighborhood Hits	598	Shared Neighborhood Hits	585
SwissProt Accessions	Q96RU8, O15180, Q9H2Y8	Gene names	TRIB1, C8FW, GIG2, TRB1
Domain Architecture	No domain graphic available
Description	Tribbles homolog 1 (TRB-1) (SKIP1) (G-protein-coupled receptor-induced protein 2) (GIG-2).

BLK_MOUSE
θ value	1.99992e-07 (rank : 687)	NC score	0.670018 (rank : 681)
Query Neighborhood Hits	1959	Target Neighborhood Hits	992	Shared Neighborhood Hits	819
SwissProt Accessions	P16277	Gene names	Blk
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

CSK22_HUMAN
θ value	1.99992e-07 (rank : 688)	NC score	0.799197 (rank : 447)
Query Neighborhood Hits	1959	Target Neighborhood Hits	758	Shared Neighborhood Hits	754
SwissProt Accessions	P19784	Gene names	CSNK2A2, CK2A2
Domain Architecture
Description	Casein kinase II subunit alpha' (EC 2.7.11.1) (CK II).

CSK22_MOUSE
θ value	1.99992e-07 (rank : 689)	NC score	0.799186 (rank : 448)
Query Neighborhood Hits	1959	Target Neighborhood Hits	758	Shared Neighborhood Hits	754
SwissProt Accessions	O54833	Gene names	Csnk2a2
Domain Architecture
Description	Casein kinase II subunit alpha' (EC 2.7.11.1) (CK II).

JAK3_MOUSE
θ value	1.99992e-07 (rank : 690)	NC score	0.732243 (rank : 572)
Query Neighborhood Hits	1959	Target Neighborhood Hits	821	Shared Neighborhood Hits	795
SwissProt Accessions	Q62137, Q61746, Q61747	Gene names	Jak3
Domain Architecture
Description	Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3).

KIRR3_MOUSE
θ value	1.99992e-07 (rank : 691)	NC score	0.298332 (rank : 947)
Query Neighborhood Hits	1959	Target Neighborhood Hits	292	Shared Neighborhood Hits	226
SwissProt Accessions	Q8BR86, Q6P555, Q810H3, Q8BGQ5, Q8BRS8	Gene names	Kirrel3, Kiaa1867
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 3 precursor (Kin of irregular chiasm-like protein 3).

MP2K3_MOUSE
θ value	1.99992e-07 (rank : 692)	NC score	0.808867 (rank : 403)
Query Neighborhood Hits	1959	Target Neighborhood Hits	826	Shared Neighborhood Hits	811
SwissProt Accessions	O09110, P97293, Q91VX1	Gene names	Map2k3, Mkk3, Prkmk3
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 3 (EC 2.7.12.2) (MAP kinase kinase 3) (MAPKK 3) (MAPK/ERK kinase 3).

TRIB1_MOUSE
θ value	1.99992e-07 (rank : 693)	NC score	0.742171 (rank : 559)
Query Neighborhood Hits	1959	Target Neighborhood Hits	593	Shared Neighborhood Hits	584
SwissProt Accessions	Q8K4K4, Q8BFS7, Q8BJR9, Q8BZX3, Q91W04	Gene names	Trib1, Trb1
Domain Architecture	No domain graphic available
Description	Tribbles homolog 1 (TRB-1).

VCAM1_MOUSE
θ value	1.99992e-07 (rank : 694)	NC score	0.341678 (rank : 917)
Query Neighborhood Hits	1959	Target Neighborhood Hits	320	Shared Neighborhood Hits	253
SwissProt Accessions	P29533	Gene names	Vcam1, Vcam-1
Domain Architecture
Description	Vascular cell adhesion protein 1 precursor (V-CAM 1).

CSK_HUMAN
θ value	2.61198e-07 (rank : 695)	NC score	0.687598 (rank : 643)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1009	Shared Neighborhood Hits	819
SwissProt Accessions	P41240, Q6FGZ6	Gene names	CSK
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase CYL).

E2AK3_HUMAN
θ value	2.61198e-07 (rank : 696)	NC score	0.804164 (rank : 434)
Query Neighborhood Hits	1959	Target Neighborhood Hits	859	Shared Neighborhood Hits	820
SwissProt Accessions	Q9NZJ5, O95846	Gene names	EIF2AK3, PEK, PERK
Domain Architecture
Description	Eukaryotic translation initiation factor 2-alpha kinase 3 precursor (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase) (HsPEK).

FGR_HUMAN
θ value	2.61198e-07 (rank : 697)	NC score	0.655190 (rank : 724)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1067	Shared Neighborhood Hits	829
SwissProt Accessions	P09769, Q9UIQ3	Gene names	FGR, SRC2
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

ITK_HUMAN
θ value	2.61198e-07 (rank : 698)	NC score	0.688406 (rank : 640)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1016	Shared Neighborhood Hits	819
SwissProt Accessions	Q08881	Gene names	ITK, EMT, LYK
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT).

KIRR3_HUMAN
θ value	2.61198e-07 (rank : 699)	NC score	0.300046 (rank : 943)
Query Neighborhood Hits	1959	Target Neighborhood Hits	302	Shared Neighborhood Hits	232
SwissProt Accessions	Q8IZU9, Q6UWJ9, Q6UWL5, Q96JG0	Gene names	KIRREL3, KIAA1867, NEPH2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 3 precursor (Kin of irregular chiasm-like protein 3) (Nephrin-like 2).

SRC_HUMAN
θ value	2.61198e-07 (rank : 700)	NC score	0.663631 (rank : 698)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1058	Shared Neighborhood Hits	823
SwissProt Accessions	P12931, Q86VB9, Q9H5A8	Gene names	SRC, SRC1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c- Src) (pp60c-src).

WEE1B_MOUSE
θ value	2.61198e-07 (rank : 701)	NC score	0.758041 (rank : 542)
Query Neighborhood Hits	1959	Target Neighborhood Hits	765	Shared Neighborhood Hits	736
SwissProt Accessions	Q66JT0, Q4U4S4, Q7TPV9	Gene names	Wee1b, Wee2
Domain Architecture	No domain graphic available
Description	Wee1-like protein kinase 1B (EC 2.7.10.2) (Wee1B kinase) (mWee1B).

CD2L6_HUMAN
θ value	3.41135e-07 (rank : 702)	NC score	0.789379 (rank : 474)
Query Neighborhood Hits	1959	Target Neighborhood Hits	844	Shared Neighborhood Hits	810
SwissProt Accessions	Q9BWU1, Q5JQZ7, Q5JR00, Q8TC78, Q9UPX2	Gene names	CDC2L6, CDK11, KIAA1028
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 6 (EC 2.7.11.22) (CDC2- related protein kinase 6) (Death-preventing kinase) (Cyclin-dependent kinase 11).

CD2L6_MOUSE
θ value	3.41135e-07 (rank : 703)	NC score	0.789542 (rank : 473)
Query Neighborhood Hits	1959	Target Neighborhood Hits	851	Shared Neighborhood Hits	814
SwissProt Accessions	Q8BWD8, Q80TM1	Gene names	Cdc2l6, Kiaa1028
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 6 (EC 2.7.11.22) (CDC2- related protein kinase 6).

FGR_MOUSE
θ value	3.41135e-07 (rank : 704)	NC score	0.652278 (rank : 729)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1069	Shared Neighborhood Hits	826
SwissProt Accessions	P14234, Q61404	Gene names	Fgr
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

KC1G1_HUMAN
θ value	3.41135e-07 (rank : 705)	NC score	0.654840 (rank : 726)
Query Neighborhood Hits	1959	Target Neighborhood Hits	708	Shared Neighborhood Hits	700
SwissProt Accessions	Q9HCP0, Q96AE9, Q9HCP1	Gene names	CSNK1G1
Domain Architecture
Description	Casein kinase I isoform gamma-1 (EC 2.7.11.1) (CKI-gamma 1).

KC1G1_MOUSE
θ value	3.41135e-07 (rank : 706)	NC score	0.656840 (rank : 718)
Query Neighborhood Hits	1959	Target Neighborhood Hits	713	Shared Neighborhood Hits	703
SwissProt Accessions	Q8BTH8	Gene names	Csnk1g1
Domain Architecture
Description	Casein kinase I isoform gamma-1 (EC 2.7.11.1) (CKI-gamma 1).

LIMK2_HUMAN
θ value	3.41135e-07 (rank : 707)	NC score	0.750955 (rank : 550)
Query Neighborhood Hits	1959	Target Neighborhood Hits	986	Shared Neighborhood Hits	813
SwissProt Accessions	P53671, Q7KZ80, Q96E10, Q99464	Gene names	LIMK2
Domain Architecture
Description	LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2).

STK16_MOUSE
θ value	3.41135e-07 (rank : 708)	NC score	0.812350 (rank : 383)
Query Neighborhood Hits	1959	Target Neighborhood Hits	824	Shared Neighborhood Hits	804
SwissProt Accessions	O88697, Q9JMJ0, Q9JMJ1, Q9QX00	Gene names	Stk16, Edpk, Krct, Mpsk1, Pkl12, Tsf1
Domain Architecture
Description	Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Protein kinase PKL12) (Myristoylated and palmitoylated serine/threonine-protein kinase) (MPSK) (TGF-beta-stimulated factor 1) (TSF-1) (Protein kinase Krct).

EPHA1_HUMAN
θ value	4.45536e-07 (rank : 709)	NC score	0.647927 (rank : 733)
Query Neighborhood Hits	1959	Target Neighborhood Hits	997	Shared Neighborhood Hits	843
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

EPHA4_HUMAN
θ value	4.45536e-07 (rank : 710)	NC score	0.661188 (rank : 704)
Query Neighborhood Hits	1959	Target Neighborhood Hits	975	Shared Neighborhood Hits	866
SwissProt Accessions	P54764	Gene names	EPHA4, HEK8, SEK
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8).

EPHA4_MOUSE
θ value	4.45536e-07 (rank : 711)	NC score	0.662168 (rank : 703)
Query Neighborhood Hits	1959	Target Neighborhood Hits	982	Shared Neighborhood Hits	868
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

EPHA7_HUMAN
θ value	4.45536e-07 (rank : 712)	NC score	0.673908 (rank : 669)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1053	Shared Neighborhood Hits	879
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

F5006_HUMAN
θ value	4.45536e-07 (rank : 713)	NC score	0.812615 (rank : 380)
Query Neighborhood Hits	1959	Target Neighborhood Hits	794	Shared Neighborhood Hits	782
SwissProt Accessions	Q96LW2, Q49A48	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase FLJ25006 (EC 2.7.11.1).

FGFR4_MOUSE
θ value	4.45536e-07 (rank : 714)	NC score	0.715085 (rank : 596)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1026	Shared Neighborhood Hits	983
SwissProt Accessions	Q03142, Q5J7D9, Q8C3V5, Q8CIB8	Gene names	Fgfr4, Fgfr-4, Mpk-11
Domain Architecture
Description	Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1) (FGFR-4) (Protein-tyrosine kinase receptor MPK-11) (CD334 antigen).

LIMK2_MOUSE
θ value	4.45536e-07 (rank : 715)	NC score	0.748293 (rank : 554)
Query Neighborhood Hits	1959	Target Neighborhood Hits	998	Shared Neighborhood Hits	812
SwissProt Accessions	O54785, O54776, O55238, Q9QUL4	Gene names	Limk2
Domain Architecture
Description	LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2).

NPHN_MOUSE
θ value	4.45536e-07 (rank : 716)	NC score	0.335817 (rank : 919)
Query Neighborhood Hits	1959	Target Neighborhood Hits	370	Shared Neighborhood Hits	276
SwissProt Accessions	Q9QZS7	Gene names	Nphs1, Nphn
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

SRC_MOUSE
θ value	4.45536e-07 (rank : 717)	NC score	0.664777 (rank : 695)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1033	Shared Neighborhood Hits	826
SwissProt Accessions	P05480	Gene names	Src
Domain Architecture
Description	Neuronal proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c-Src) (pp60c-src).

SRRM1_MOUSE
θ value	4.45536e-07 (rank : 718)	NC score	0.133089 (rank : 1074)
Query Neighborhood Hits	1959	Target Neighborhood Hits	966	Shared Neighborhood Hits	417
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

TNK1_MOUSE
θ value	4.45536e-07 (rank : 719)	NC score	0.679516 (rank : 658)
Query Neighborhood Hits	1959	Target Neighborhood Hits	806	Shared Neighborhood Hits	770
SwissProt Accessions	Q99ML2, Q8CCC4, Q8K0X9, Q91V11	Gene names	Tnk1, Kos1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (Kinase of embryonic stem cells).

CDK8_HUMAN
θ value	5.81887e-07 (rank : 720)	NC score	0.786461 (rank : 485)
Query Neighborhood Hits	1959	Target Neighborhood Hits	831	Shared Neighborhood Hits	807
SwissProt Accessions	P49336	Gene names	CDK8
Domain Architecture
Description	Cell division protein kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Protein kinase K35).

CLK1_MOUSE
θ value	5.81887e-07 (rank : 721)	NC score	0.760622 (rank : 539)
Query Neighborhood Hits	1959	Target Neighborhood Hits	760	Shared Neighborhood Hits	749
SwissProt Accessions	P22518	Gene names	Clk1, Clk, Sty
Domain Architecture
Description	Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1) (Protein kinase STY).

EPHA7_MOUSE
θ value	5.81887e-07 (rank : 722)	NC score	0.673625 (rank : 670)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1025	Shared Neighborhood Hits	875
SwissProt Accessions	Q61772, Q61505, Q61773, Q61774	Gene names	Epha7, Ebk, Ehk3, Mdk1
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1).

LRRK1_HUMAN
θ value	5.81887e-07 (rank : 723)	NC score	0.715513 (rank : 595)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1237	Shared Neighborhood Hits	832
SwissProt Accessions	Q38SD2, Q6NVH5, Q6NYC0, Q6ZNL9, Q6ZNM9, Q96JN5, Q9H5S3	Gene names	LRRK1, KIAA1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

MUC1_HUMAN
θ value	5.81887e-07 (rank : 724)	NC score	0.082289 (rank : 1163)
Query Neighborhood Hits	1959	Target Neighborhood Hits	975	Shared Neighborhood Hits	398
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

RON_HUMAN
θ value	5.81887e-07 (rank : 725)	NC score	0.652470 (rank : 728)
Query Neighborhood Hits	1959	Target Neighborhood Hits	842	Shared Neighborhood Hits	794
SwissProt Accessions	Q04912	Gene names	MST1R, RON
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (CDw136 antigen) [Contains: Macrophage- stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

ROR1_MOUSE
θ value	5.81887e-07 (rank : 726)	NC score	0.708069 (rank : 608)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1025	Shared Neighborhood Hits	968
SwissProt Accessions	Q9Z139	Gene names	Ror1, Ntrkr1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1) (mROR1).

TRIB3_MOUSE
θ value	5.81887e-07 (rank : 727)	NC score	0.731044 (rank : 574)
Query Neighborhood Hits	1959	Target Neighborhood Hits	578	Shared Neighborhood Hits	571
SwissProt Accessions	Q8K4K2, Q3UMQ0, Q921E7	Gene names	Trib3, Nipk, Trb3
Domain Architecture
Description	Tribbles homolog 3 (TRB-3) (Neuronal cell death-inducible putative kinase).

VCAM1_HUMAN
θ value	5.81887e-07 (rank : 728)	NC score	0.340304 (rank : 918)
Query Neighborhood Hits	1959	Target Neighborhood Hits	352	Shared Neighborhood Hits	249
SwissProt Accessions	P19320, Q6NUP8	Gene names	VCAM1, L1CAM
Domain Architecture
Description	Vascular cell adhesion protein 1 precursor (V-CAM 1) (CD106 antigen) (INCAM-100).

CLK1_HUMAN
θ value	7.59969e-07 (rank : 729)	NC score	0.760449 (rank : 540)
Query Neighborhood Hits	1959	Target Neighborhood Hits	756	Shared Neighborhood Hits	741
SwissProt Accessions	P49759	Gene names	CLK1, CLK
Domain Architecture
Description	Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1).

CLK4_MOUSE
θ value	7.59969e-07 (rank : 730)	NC score	0.754958 (rank : 544)
Query Neighborhood Hits	1959	Target Neighborhood Hits	759	Shared Neighborhood Hits	745
SwissProt Accessions	O35493, O35721, Q8CEU9, Q99LU6	Gene names	Clk4
Domain Architecture
Description	Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4).

EPHB1_HUMAN
θ value	7.59969e-07 (rank : 731)	NC score	0.674647 (rank : 668)
Query Neighborhood Hits	1959	Target Neighborhood Hits	988	Shared Neighborhood Hits	864
SwissProt Accessions	P54762, O43569, O95142, O95143	Gene names	EPHB1, EPHT2, NET
Domain Architecture
Description	Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK).

F5006_MOUSE
θ value	7.59969e-07 (rank : 732)	NC score	0.816639 (rank : 360)
Query Neighborhood Hits	1959	Target Neighborhood Hits	793	Shared Neighborhood Hits	785
SwissProt Accessions	Q5SYL1	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase FLJ25006 (EC 2.7.11.1).

FGFR3_MOUSE
θ value	7.59969e-07 (rank : 733)	NC score	0.741812 (rank : 560)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1059	Shared Neighborhood Hits	1002
SwissProt Accessions	Q61851, Q61564, Q63834	Gene names	Fgfr3, Mfr3, Sam3
Domain Architecture
Description	Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1) (FGFR-3) (Heparin-binding growth factor receptor) (CD333 antigen).

FYN_HUMAN
θ value	7.59969e-07 (rank : 734)	NC score	0.668767 (rank : 683)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1078	Shared Neighborhood Hits	831
SwissProt Accessions	P06241	Gene names	FYN
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK).

PTK6_HUMAN
θ value	7.59969e-07 (rank : 735)	NC score	0.709376 (rank : 607)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1020	Shared Neighborhood Hits	819
SwissProt Accessions	Q13882	Gene names	PTK6, BRK
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK).

JAK1_MOUSE
θ value	9.92553e-07 (rank : 736)	NC score	0.709528 (rank : 606)
Query Neighborhood Hits	1959	Target Neighborhood Hits	854	Shared Neighborhood Hits	809
SwissProt Accessions	P52332, Q62126	Gene names	Jak1
Domain Architecture
Description	Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1).

ROR1_HUMAN
θ value	9.92553e-07 (rank : 737)	NC score	0.706523 (rank : 610)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1018	Shared Neighborhood Hits	961
SwissProt Accessions	Q01973, Q92776	Gene names	ROR1, NTRKR1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1).

SIG11_HUMAN
θ value	9.92553e-07 (rank : 738)	NC score	0.281900 (rank : 964)
Query Neighborhood Hits	1959	Target Neighborhood Hits	273	Shared Neighborhood Hits	241
SwissProt Accessions	Q96RL6	Gene names	SIGLEC11
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 11 precursor (Siglec-11) (Sialic acid-binding lectin 11).

STK16_HUMAN
θ value	9.92553e-07 (rank : 739)	NC score	0.813081 (rank : 377)
Query Neighborhood Hits	1959	Target Neighborhood Hits	824	Shared Neighborhood Hits	808
SwissProt Accessions	O75716, Q96KI2, Q9UEN3, Q9UP78	Gene names	STK16, MPSK1, PKL12, TSF1
Domain Architecture
Description	Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Protein kinase PKL12) (Myristoylated and palmitoylated serine/threonine-protein kinase) (MPSK) (TGF-beta-stimulated factor 1) (TSF-1) (hPSK).

WEE1_HUMAN
θ value	9.92553e-07 (rank : 740)	NC score	0.777871 (rank : 505)
Query Neighborhood Hits	1959	Target Neighborhood Hits	777	Shared Neighborhood Hits	748
SwissProt Accessions	P30291	Gene names	WEE1
Domain Architecture
Description	Wee1-like protein kinase (EC 2.7.10.2) (Wee1A kinase) (WEE1hu).

YES_HUMAN
θ value	9.92553e-07 (rank : 741)	NC score	0.660021 (rank : 711)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1059	Shared Neighborhood Hits	821
SwissProt Accessions	P07947	Gene names	YES1, YES
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

ZAP70_HUMAN
θ value	9.92553e-07 (rank : 742)	NC score	0.699039 (rank : 618)
Query Neighborhood Hits	1959	Target Neighborhood Hits	893	Shared Neighborhood Hits	804
SwissProt Accessions	P43403	Gene names	ZAP70, SRK
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

CD22_MOUSE
θ value	1.29631e-06 (rank : 743)	NC score	0.312405 (rank : 934)
Query Neighborhood Hits	1959	Target Neighborhood Hits	331	Shared Neighborhood Hits	233
SwissProt Accessions	P35329, Q9JHL2, Q9JJX9, Q9JJY0, Q9JJY1, Q9R056, Q9R094, Q9WU51	Gene names	Cd22, Lyb-8
Domain Architecture
Description	B-cell receptor CD22 precursor (Leu-14) (B-lymphocyte cell adhesion molecule) (BL-CAM) (Siglec-2).

CLK4_HUMAN
θ value	1.29631e-06 (rank : 744)	NC score	0.756087 (rank : 543)
Query Neighborhood Hits	1959	Target Neighborhood Hits	759	Shared Neighborhood Hits	746
SwissProt Accessions	Q9HAZ1	Gene names	CLK4
Domain Architecture
Description	Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4).

EPHA2_MOUSE
θ value	1.29631e-06 (rank : 745)	NC score	0.660037 (rank : 710)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1020	Shared Neighborhood Hits	862
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

FYN_MOUSE
θ value	1.29631e-06 (rank : 746)	NC score	0.663793 (rank : 697)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1073	Shared Neighborhood Hits	833
SwissProt Accessions	P39688	Gene names	Fyn
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn).

KC1G3_HUMAN
θ value	1.29631e-06 (rank : 747)	NC score	0.651434 (rank : 730)
Query Neighborhood Hits	1959	Target Neighborhood Hits	711	Shared Neighborhood Hits	705
SwissProt Accessions	Q9Y6M4, Q86WZ7, Q9Y6M3	Gene names	CSNK1G3
Domain Architecture
Description	Casein kinase I isoform gamma-3 (EC 2.7.11.1) (CKI-gamma 3).

ROBO4_MOUSE
θ value	1.29631e-06 (rank : 748)	NC score	0.361433 (rank : 898)
Query Neighborhood Hits	1959	Target Neighborhood Hits	358	Shared Neighborhood Hits	281
SwissProt Accessions	Q8C310, Q9DBW1	Gene names	Robo4
Domain Architecture
Description	Roundabout homolog 4 precursor.

STYK1_MOUSE
θ value	1.29631e-06 (rank : 749)	NC score	0.642407 (rank : 746)
Query Neighborhood Hits	1959	Target Neighborhood Hits	779	Shared Neighborhood Hits	757
SwissProt Accessions	Q6J9G1, Q8BZH6, Q8BZT1	Gene names	Styk1, Nok
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (mNOK).

YES_MOUSE
θ value	1.29631e-06 (rank : 750)	NC score	0.659351 (rank : 712)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1052	Shared Neighborhood Hits	818
SwissProt Accessions	Q04736	Gene names	Yes1, Yes
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

ATL3_HUMAN
θ value	1.69304e-06 (rank : 751)	NC score	0.214609 (rank : 1006)
Query Neighborhood Hits	1959	Target Neighborhood Hits	414	Shared Neighborhood Hits	263
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

EPHA1_MOUSE
θ value	1.69304e-06 (rank : 752)	NC score	0.639627 (rank : 749)
Query Neighborhood Hits	1959	Target Neighborhood Hits	958	Shared Neighborhood Hits	837
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

EPHA5_HUMAN
θ value	1.69304e-06 (rank : 753)	NC score	0.666492 (rank : 688)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1009	Shared Neighborhood Hits	875
SwissProt Accessions	P54756	Gene names	EPHA5, EHK1, HEK7
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein- tyrosine kinase HEK7).

KSYK_MOUSE
θ value	1.69304e-06 (rank : 754)	NC score	0.699549 (rank : 616)
Query Neighborhood Hits	1959	Target Neighborhood Hits	944	Shared Neighborhood Hits	820
SwissProt Accessions	P48025	Gene names	Syk
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

NPHN_HUMAN
θ value	1.69304e-06 (rank : 755)	NC score	0.342150 (rank : 916)
Query Neighborhood Hits	1959	Target Neighborhood Hits	362	Shared Neighborhood Hits	277
SwissProt Accessions	O60500	Gene names	NPHS1, NPHN
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

E2AK1_MOUSE
θ value	2.21117e-06 (rank : 756)	NC score	0.806358 (rank : 414)
Query Neighborhood Hits	1959	Target Neighborhood Hits	821	Shared Neighborhood Hits	801
SwissProt Accessions	Q9Z2R9, Q8C024, Q8K123, Q9CTP5, Q9D601	Gene names	Eif2ak1, Hri
Domain Architecture
Description	Eukaryotic translation initiation factor 2-alpha kinase 1 (EC 2.7.11.1) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Heme-controlled repressor) (HCR) (Hemin-sensitive initiation factor 2-alpha kinase).

EPHA2_HUMAN
θ value	2.21117e-06 (rank : 757)	NC score	0.662755 (rank : 701)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1021	Shared Neighborhood Hits	871
SwissProt Accessions	P29317	Gene names	EPHA2, ECK
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase).

KIRR2_MOUSE
θ value	2.21117e-06 (rank : 758)	NC score	0.312117 (rank : 935)
Query Neighborhood Hits	1959	Target Neighborhood Hits	326	Shared Neighborhood Hits	238
SwissProt Accessions	Q7TSU7, Q7TQ98	Gene names	Kirrel2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2).

NACAM_MOUSE
θ value	2.21117e-06 (rank : 759)	NC score	0.124885 (rank : 1083)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1866	Shared Neighborhood Hits	634
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

DDR2_HUMAN
θ value	2.88788e-06 (rank : 760)	NC score	0.635407 (rank : 750)
Query Neighborhood Hits	1959	Target Neighborhood Hits	818	Shared Neighborhood Hits	765
SwissProt Accessions	Q16832	Gene names	DDR2, NTRKR3, TKT, TYRO10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

EPHA3_HUMAN
θ value	2.88788e-06 (rank : 761)	NC score	0.672492 (rank : 674)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1005	Shared Neighborhood Hits	885
SwissProt Accessions	P29320, Q9H2V3, Q9H2V4	Gene names	EPHA3, ETK, ETK1, HEK
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4).

KC1G2_HUMAN
θ value	2.88788e-06 (rank : 762)	NC score	0.625601 (rank : 761)
Query Neighborhood Hits	1959	Target Neighborhood Hits	693	Shared Neighborhood Hits	686
SwissProt Accessions	P78368, O00704, Q8WUB1	Gene names	CSNK1G2
Domain Architecture
Description	Casein kinase I isoform gamma-2 (EC 2.7.11.1) (CKI-gamma 2).

KSYK_HUMAN
θ value	2.88788e-06 (rank : 763)	NC score	0.699198 (rank : 617)
Query Neighborhood Hits	1959	Target Neighborhood Hits	901	Shared Neighborhood Hits	799
SwissProt Accessions	P43405	Gene names	SYK
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

SRRM2_MOUSE
θ value	2.88788e-06 (rank : 764)	NC score	0.123688 (rank : 1090)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1470	Shared Neighborhood Hits	506
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

WEE1B_HUMAN
θ value	2.88788e-06 (rank : 765)	NC score	0.760313 (rank : 541)
Query Neighborhood Hits	1959	Target Neighborhood Hits	836	Shared Neighborhood Hits	760
SwissProt Accessions	P0C1S8	Gene names	WEE1B, WEE2
Domain Architecture	No domain graphic available
Description	Wee1-like protein kinase 1B (EC 2.7.10.2) (Wee1B kinase).

BLK_HUMAN
θ value	3.77169e-06 (rank : 766)	NC score	0.671195 (rank : 679)
Query Neighborhood Hits	1959	Target Neighborhood Hits	994	Shared Neighborhood Hits	821
SwissProt Accessions	P51451, Q16291	Gene names	BLK
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

EPHA5_MOUSE
θ value	3.77169e-06 (rank : 767)	NC score	0.677823 (rank : 662)
Query Neighborhood Hits	1959	Target Neighborhood Hits	950	Shared Neighborhood Hits	860
SwissProt Accessions	Q60629	Gene names	Epha5, Bsk, Cek7, Ehk1
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7).

RAGE_MOUSE
θ value	3.77169e-06 (rank : 768)	NC score	0.308866 (rank : 940)
Query Neighborhood Hits	1959	Target Neighborhood Hits	295	Shared Neighborhood Hits	220
SwissProt Accessions	Q62151	Gene names	Ager, Rage
Domain Architecture
Description	Advanced glycosylation end product-specific receptor precursor (Receptor for advanced glycosylation end products).

RON_MOUSE
θ value	3.77169e-06 (rank : 769)	NC score	0.641409 (rank : 747)
Query Neighborhood Hits	1959	Target Neighborhood Hits	836	Shared Neighborhood Hits	785
SwissProt Accessions	Q62190, Q62555	Gene names	Mst1r, Ron, Stk
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

TIE2_HUMAN
θ value	3.77169e-06 (rank : 770)	NC score	0.688459 (rank : 639)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1192	Shared Neighborhood Hits	888
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

FGFR4_HUMAN
θ value	4.92598e-06 (rank : 771)	NC score	0.733870 (rank : 569)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1037	Shared Neighborhood Hits	995
SwissProt Accessions	P22455, O43785, Q14309	Gene names	FGFR4, JTK2, TKF
Domain Architecture
Description	Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1) (FGFR-4) (CD334 antigen).

NFH_MOUSE
θ value	4.92598e-06 (rank : 772)	NC score	0.074492 (rank : 1191)
Query Neighborhood Hits	1959	Target Neighborhood Hits	2247	Shared Neighborhood Hits	613
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

TIE2_MOUSE
θ value	4.92598e-06 (rank : 773)	NC score	0.688196 (rank : 641)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1204	Shared Neighborhood Hits	888
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

EPHB2_HUMAN
θ value	6.43352e-06 (rank : 774)	NC score	0.658521 (rank : 714)
Query Neighborhood Hits	1959	Target Neighborhood Hits	983	Shared Neighborhood Hits	859
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

EPHB2_MOUSE
θ value	6.43352e-06 (rank : 775)	NC score	0.658694 (rank : 713)
Query Neighborhood Hits	1959	Target Neighborhood Hits	982	Shared Neighborhood Hits	859
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

KC1G2_MOUSE
θ value	6.43352e-06 (rank : 776)	NC score	0.626672 (rank : 760)
Query Neighborhood Hits	1959	Target Neighborhood Hits	695	Shared Neighborhood Hits	686
SwissProt Accessions	Q8BVP5	Gene names	Csnk1g2
Domain Architecture	No domain graphic available
Description	Casein kinase I isoform gamma-2 (EC 2.7.11.1) (CKI-gamma 2).

STK35_HUMAN
θ value	6.43352e-06 (rank : 777)	NC score	0.828013 (rank : 299)
Query Neighborhood Hits	1959	Target Neighborhood Hits	825	Shared Neighborhood Hits	804
SwissProt Accessions	Q8TDR2, Q5T3R1, Q5T3R2, Q96AB4, Q9BZ06	Gene names	STK35, CLIK1, PDIK1
Domain Architecture
Description	Serine/threonine-protein kinase 35 (EC 2.7.11.1) (CLP-36-interacting kinase) (Clik1) (PDLIM1-interacting kinase 1).

ALK_MOUSE
θ value	8.40245e-06 (rank : 778)	NC score	0.604993 (rank : 780)
Query Neighborhood Hits	1959	Target Neighborhood Hits	811	Shared Neighborhood Hits	739
SwissProt Accessions	P97793	Gene names	Alk
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

E2AK1_HUMAN
θ value	8.40245e-06 (rank : 779)	NC score	0.801546 (rank : 442)
Query Neighborhood Hits	1959	Target Neighborhood Hits	833	Shared Neighborhood Hits	804
SwissProt Accessions	Q9BQI3, Q8NBW3, Q9HC02, Q9NYE0, Q9P0V6, Q9P1J5, Q9P2H8, Q9UHG4	Gene names	EIF2AK1, HRI, KIAA1369
Domain Architecture
Description	Eukaryotic translation initiation factor 2-alpha kinase 1 (EC 2.7.11.1) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Heme-controlled repressor) (HCR) (Hemin-sensitive initiation factor 2-alpha kinase).

INSR_MOUSE
θ value	8.40245e-06 (rank : 780)	NC score	0.644590 (rank : 739)
Query Neighborhood Hits	1959	Target Neighborhood Hits	968	Shared Neighborhood Hits	825
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

RET_HUMAN
θ value	8.40245e-06 (rank : 781)	NC score	0.666885 (rank : 686)
Query Neighborhood Hits	1959	Target Neighborhood Hits	873	Shared Neighborhood Hits	795
SwissProt Accessions	P07949, Q15250	Gene names	RET
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

VRK1_MOUSE
θ value	8.40245e-06 (rank : 782)	NC score	0.487504 (rank : 818)
Query Neighborhood Hits	1959	Target Neighborhood Hits	583	Shared Neighborhood Hits	573
SwissProt Accessions	Q80X41, O88635, O88636, Q8C2P7, Q91YH9	Gene names	Vrk1
Domain Architecture
Description	Serine/threonine-protein kinase VRK1 (EC 2.7.11.1) (Vaccinia-related kinase 1) (Serine/threonine-protein kinase 51PK).

AVR2B_HUMAN
θ value	1.09739e-05 (rank : 783)	NC score	0.629437 (rank : 757)
Query Neighborhood Hits	1959	Target Neighborhood Hits	748	Shared Neighborhood Hits	728
SwissProt Accessions	Q13705, Q4VAV0	Gene names	ACVR2B
Domain Architecture
Description	Activin receptor type 2B precursor (EC 2.7.11.30) (Activin receptor type IIB) (ACTR-IIB).

AVR2B_MOUSE
θ value	1.09739e-05 (rank : 784)	NC score	0.629644 (rank : 756)
Query Neighborhood Hits	1959	Target Neighborhood Hits	749	Shared Neighborhood Hits	728
SwissProt Accessions	P27040	Gene names	Acvr2b
Domain Architecture
Description	Activin receptor type 2B precursor (EC 2.7.11.30) (Activin receptor type IIB) (ACTR-IIB).

LTK_HUMAN
θ value	1.09739e-05 (rank : 785)	NC score	0.598945 (rank : 784)
Query Neighborhood Hits	1959	Target Neighborhood Hits	774	Shared Neighborhood Hits	740
SwissProt Accessions	P29376	Gene names	LTK, TYK1
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1) (Protein tyrosine kinase 1).

CLK3_HUMAN
θ value	1.43324e-05 (rank : 786)	NC score	0.728992 (rank : 577)
Query Neighborhood Hits	1959	Target Neighborhood Hits	748	Shared Neighborhood Hits	730
SwissProt Accessions	P49761, Q9BRS3, Q9BUJ7	Gene names	CLK3
Domain Architecture
Description	Dual specificity protein kinase CLK3 (EC 2.7.12.1) (CDC-like kinase 3).

CLK3_MOUSE
θ value	1.43324e-05 (rank : 787)	NC score	0.728341 (rank : 578)
Query Neighborhood Hits	1959	Target Neighborhood Hits	761	Shared Neighborhood Hits	732
SwissProt Accessions	O35492	Gene names	Clk3
Domain Architecture
Description	Dual specificity protein kinase CLK3 (EC 2.7.12.1) (CDC-like kinase 3).

DDR2_MOUSE
θ value	1.43324e-05 (rank : 788)	NC score	0.641182 (rank : 748)
Query Neighborhood Hits	1959	Target Neighborhood Hits	813	Shared Neighborhood Hits	767
SwissProt Accessions	Q62371	Gene names	Ddr2, Ntrkr3, Tkt, Tyro10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

FSTL4_HUMAN
θ value	1.43324e-05 (rank : 789)	NC score	0.315393 (rank : 931)
Query Neighborhood Hits	1959	Target Neighborhood Hits	344	Shared Neighborhood Hits	260
SwissProt Accessions	Q6MZW2, Q8TBU0, Q9UPU1	Gene names	FSTL4, KIAA1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4).

NTRK1_HUMAN
θ value	1.43324e-05 (rank : 790)	NC score	0.660095 (rank : 709)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1023	Shared Neighborhood Hits	876
SwissProt Accessions	P04629, P08119, Q15655, Q15656, Q5D056, Q5VZS2, Q9UIU7	Gene names	NTRK1, TRK
Domain Architecture
Description	High affinity nerve growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1 transforming tyrosine kinase protein) (p140-TrkA) (Trk-A).

PGFRA_HUMAN
θ value	1.43324e-05 (rank : 791)	NC score	0.663313 (rank : 699)
Query Neighborhood Hits	1959	Target Neighborhood Hits	980	Shared Neighborhood Hits	928
SwissProt Accessions	P16234, Q96KZ7	Gene names	PDGFRA
Domain Architecture
Description	Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen).

PGFRA_MOUSE
θ value	1.43324e-05 (rank : 792)	NC score	0.660562 (rank : 708)
Query Neighborhood Hits	1959	Target Neighborhood Hits	975	Shared Neighborhood Hits	924
SwissProt Accessions	P26618, Q62046	Gene names	Pdgfra
Domain Architecture
Description	Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen).

PGFRB_HUMAN
θ value	1.43324e-05 (rank : 793)	NC score	0.649523 (rank : 732)
Query Neighborhood Hits	1959	Target Neighborhood Hits	962	Shared Neighborhood Hits	919
SwissProt Accessions	P09619, Q8N5L4	Gene names	PDGFRB
Domain Architecture
Description	Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen).

ROBO4_HUMAN
θ value	1.43324e-05 (rank : 794)	NC score	0.357853 (rank : 904)
Query Neighborhood Hits	1959	Target Neighborhood Hits	364	Shared Neighborhood Hits	292
SwissProt Accessions	Q8WZ75, Q8TEG1, Q96JV6, Q9H718, Q9NWJ8	Gene names	ROBO4
Domain Architecture
Description	Roundabout homolog 4 precursor (Magic roundabout).

ZAP70_MOUSE
θ value	1.43324e-05 (rank : 795)	NC score	0.697198 (rank : 623)
Query Neighborhood Hits	1959	Target Neighborhood Hits	905	Shared Neighborhood Hits	809
SwissProt Accessions	P43404	Gene names	Zap70, Srk, Zap-70
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

EPHB4_HUMAN
θ value	1.87187e-05 (rank : 796)	NC score	0.664244 (rank : 696)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1056	Shared Neighborhood Hits	867
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

EPHB4_MOUSE
θ value	1.87187e-05 (rank : 797)	NC score	0.668855 (rank : 682)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1013	Shared Neighborhood Hits	863
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

INSR_HUMAN
θ value	1.87187e-05 (rank : 798)	NC score	0.644870 (rank : 738)
Query Neighborhood Hits	1959	Target Neighborhood Hits	963	Shared Neighborhood Hits	829
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

TNK1_HUMAN
θ value	1.87187e-05 (rank : 799)	NC score	0.672139 (rank : 677)
Query Neighborhood Hits	1959	Target Neighborhood Hits	815	Shared Neighborhood Hits	775
SwissProt Accessions	Q13470, O95364, Q8IYI4	Gene names	TNK1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1).

AAK1_HUMAN
θ value	2.44474e-05 (rank : 800)	NC score	0.785847 (rank : 487)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1077	Shared Neighborhood Hits	926
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

AAK1_MOUSE
θ value	2.44474e-05 (rank : 801)	NC score	0.783662 (rank : 495)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1051	Shared Neighborhood Hits	896
SwissProt Accessions	Q3UHJ0, Q3TY53, Q6ZPZ6, Q80XP6	Gene names	Aak1, Kiaa1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

ALK_HUMAN
θ value	2.44474e-05 (rank : 802)	NC score	0.606924 (rank : 779)
Query Neighborhood Hits	1959	Target Neighborhood Hits	795	Shared Neighborhood Hits	732
SwissProt Accessions	Q9UM73, Q9Y4K6	Gene names	ALK
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

EPHA8_MOUSE
θ value	2.44474e-05 (rank : 803)	NC score	0.658058 (rank : 715)
Query Neighborhood Hits	1959	Target Neighborhood Hits	969	Shared Neighborhood Hits	867
SwissProt Accessions	O09127	Gene names	Epha8, Eek
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase).

PINK1_HUMAN
θ value	2.44474e-05 (rank : 804)	NC score	0.725681 (rank : 583)
Query Neighborhood Hits	1959	Target Neighborhood Hits	741	Shared Neighborhood Hits	717
SwissProt Accessions	Q9BXM7, Q8N6T9, Q8NBU3, Q96DE4	Gene names	PINK1
Domain Architecture
Description	Serine/threonine-protein kinase PINK1, mitochondrial precursor (EC 2.7.11.1) (PTEN-induced putative kinase protein 1) (BRPK).

SCYL2_HUMAN
θ value	2.44474e-05 (rank : 805)	NC score	0.616772 (rank : 769)
Query Neighborhood Hits	1959	Target Neighborhood Hits	632	Shared Neighborhood Hits	566
SwissProt Accessions	Q6P3W7, Q96EF4, Q96ST4, Q9H7V5, Q9NVH3, Q9P2I7	Gene names	SCYL2, CVAK104, KIAA1360
Domain Architecture	No domain graphic available
Description	SCY1-like protein 2 (Coated vesicle-associated kinase of 104 kDa).

SIG10_HUMAN
θ value	2.44474e-05 (rank : 806)	NC score	0.277541 (rank : 973)
Query Neighborhood Hits	1959	Target Neighborhood Hits	363	Shared Neighborhood Hits	276
SwissProt Accessions	Q96LC7, Q6UXI8, Q96G54, Q96LC8	Gene names	SIGLEC10, SLG2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 10 precursor (Siglec-10) (Siglec- like protein 2).

AATK_MOUSE
θ value	3.19293e-05 (rank : 807)	NC score	0.632070 (rank : 752)
Query Neighborhood Hits	1959	Target Neighborhood Hits	942	Shared Neighborhood Hits	813
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

BMP2K_HUMAN
θ value	3.19293e-05 (rank : 808)	NC score	0.783957 (rank : 494)
Query Neighborhood Hits	1959	Target Neighborhood Hits	867	Shared Neighborhood Hits	782
SwissProt Accessions	Q9NSY1, O94791, Q8IYF2, Q8N2G7, Q8NHG9, Q9NTG8	Gene names	BMP2K, BIKE
Domain Architecture
Description	BMP-2-inducible protein kinase (EC 2.7.11.1) (BIKe).

BMP2K_MOUSE
θ value	3.19293e-05 (rank : 809)	NC score	0.785474 (rank : 490)
Query Neighborhood Hits	1959	Target Neighborhood Hits	874	Shared Neighborhood Hits	785
SwissProt Accessions	Q91Z96, Q8C8L7	Gene names	Bmp2k, Bike
Domain Architecture
Description	BMP-2-inducible protein kinase (EC 2.7.11.1) (BIKe).

MET_MOUSE
θ value	3.19293e-05 (rank : 810)	NC score	0.645478 (rank : 736)
Query Neighborhood Hits	1959	Target Neighborhood Hits	844	Shared Neighborhood Hits	785
SwissProt Accessions	P16056, Q62125	Gene names	Met
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

RIPK2_HUMAN
θ value	3.19293e-05 (rank : 811)	NC score	0.701158 (rank : 614)
Query Neighborhood Hits	1959	Target Neighborhood Hits	774	Shared Neighborhood Hits	741
SwissProt Accessions	O43353, Q6UWF0	Gene names	RIPK2, CARDIAK, RICK, RIP2
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (CARD-containing interleukin-1 beta-converting enzyme- associated kinase) (CARD-containing IL-1 beta ICE-kinase).

RIPK2_MOUSE
θ value	3.19293e-05 (rank : 812)	NC score	0.698763 (rank : 619)
Query Neighborhood Hits	1959	Target Neighborhood Hits	776	Shared Neighborhood Hits	740
SwissProt Accessions	P58801	Gene names	Ripk2
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1).

SCYL2_MOUSE
θ value	3.19293e-05 (rank : 813)	NC score	0.597534 (rank : 785)
Query Neighborhood Hits	1959	Target Neighborhood Hits	603	Shared Neighborhood Hits	542
SwissProt Accessions	Q8CFE4, Q3UT57, Q3UWU9, Q8K0M4	Gene names	Scyl2, Cvak104, D10Ertd802e
Domain Architecture	No domain graphic available
Description	SCY1-like protein 2 (Coated vesicle-associated kinase of 104 kDa).

ERBB2_MOUSE
θ value	4.1701e-05 (rank : 814)	NC score	0.647751 (rank : 734)
Query Neighborhood Hits	1959	Target Neighborhood Hits	918	Shared Neighborhood Hits	815
SwissProt Accessions	P70424, Q61525, Q6ZPE0	Gene names	Erbb2, Kiaa3023, Neu
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene).

LRFN3_HUMAN
θ value	4.1701e-05 (rank : 815)	NC score	0.179472 (rank : 1022)
Query Neighborhood Hits	1959	Target Neighborhood Hits	444	Shared Neighborhood Hits	211
SwissProt Accessions	Q9BTN0, Q6UY10	Gene names	LRFN3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 3 precursor.

NTRK3_HUMAN
θ value	4.1701e-05 (rank : 816)	NC score	0.697262 (rank : 622)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1115	Shared Neighborhood Hits	947
SwissProt Accessions	Q16288, Q12827, Q16289	Gene names	NTRK3, TRKC
Domain Architecture
Description	NT-3 growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C).

PGFRB_MOUSE
θ value	4.1701e-05 (rank : 817)	NC score	0.653334 (rank : 727)
Query Neighborhood Hits	1959	Target Neighborhood Hits	960	Shared Neighborhood Hits	913
SwissProt Accessions	P05622	Gene names	Pdgfrb, Pdgfr
Domain Architecture
Description	Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen).

RET_MOUSE
θ value	4.1701e-05 (rank : 818)	NC score	0.665401 (rank : 693)
Query Neighborhood Hits	1959	Target Neighborhood Hits	884	Shared Neighborhood Hits	795
SwissProt Accessions	P35546, Q8BQ34, Q9QXH9	Gene names	Ret
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

SRRM1_HUMAN
θ value	4.1701e-05 (rank : 819)	NC score	0.105830 (rank : 1119)
Query Neighborhood Hits	1959	Target Neighborhood Hits	690	Shared Neighborhood Hits	278
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

UHMK1_HUMAN
θ value	4.1701e-05 (rank : 820)	NC score	0.778527 (rank : 503)
Query Neighborhood Hits	1959	Target Neighborhood Hits	808	Shared Neighborhood Hits	766
SwissProt Accessions	Q8TAS1, Q96C22	Gene names	UHMK1, KIS, KIST
Domain Architecture
Description	Serine/threonine-protein kinase Kist (EC 2.7.11.1) (Kinase interacting with stathmin) (U2AF homology motif kinase 1).

UHMK1_MOUSE
θ value	4.1701e-05 (rank : 821)	NC score	0.777265 (rank : 507)
Query Neighborhood Hits	1959	Target Neighborhood Hits	809	Shared Neighborhood Hits	766
SwissProt Accessions	P97343, Q61775, Q9CYT1	Gene names	Uhmk1, Kis, Kist
Domain Architecture
Description	Serine/threonine-protein kinase Kist (EC 2.7.11.1) (Kinase interacting with stathmin) (U2AF homology motif kinase 1).

ABL2_HUMAN
θ value	5.44631e-05 (rank : 822)	NC score	0.683728 (rank : 652)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1045	Shared Neighborhood Hits	829
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

CSF1R_MOUSE
θ value	5.44631e-05 (rank : 823)	NC score	0.633504 (rank : 751)
Query Neighborhood Hits	1959	Target Neighborhood Hits	983	Shared Neighborhood Hits	933
SwissProt Accessions	P09581, Q3U3P1, Q9DBH9	Gene names	Csf1r, Csfmr, Fms
Domain Architecture
Description	Macrophage colony-stimulating factor 1 receptor precursor (EC 2.7.10.1) (CSF-1-R) (Fms proto-oncogene) (c-fms) (CD115 antigen).

ERBB2_HUMAN
θ value	5.44631e-05 (rank : 824)	NC score	0.646232 (rank : 735)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1073	Shared Neighborhood Hits	876
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

FSTL4_MOUSE
θ value	5.44631e-05 (rank : 825)	NC score	0.309889 (rank : 939)
Query Neighborhood Hits	1959	Target Neighborhood Hits	333	Shared Neighborhood Hits	255
SwissProt Accessions	Q5STE3, Q5DU03	Gene names	Fstl4, Kiaa1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4) (m- D/Bsp120I 1-1).

IGS4B_MOUSE
θ value	5.44631e-05 (rank : 826)	NC score	0.278283 (rank : 970)
Query Neighborhood Hits	1959	Target Neighborhood Hits	328	Shared Neighborhood Hits	235
SwissProt Accessions	Q99N28, Q8BSQ8, Q8K1H8	Gene names	Igsf4b, Necl1, Syncam3, Tsll1
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 4B precursor (Nectin-like protein 1) (Necl-1) (TSLC1-like protein 1) (Synaptic cell adhesion molecule 3).

LRFN4_MOUSE
θ value	5.44631e-05 (rank : 827)	NC score	0.190138 (rank : 1015)
Query Neighborhood Hits	1959	Target Neighborhood Hits	442	Shared Neighborhood Hits	213
SwissProt Accessions	Q80XU8, Q3TQG8, Q8K3C4	Gene names	Lrfn4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursor.

LTK_MOUSE
θ value	5.44631e-05 (rank : 828)	NC score	0.604208 (rank : 781)
Query Neighborhood Hits	1959	Target Neighborhood Hits	770	Shared Neighborhood Hits	736
SwissProt Accessions	P08923	Gene names	Ltk
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1).

MET_HUMAN
θ value	5.44631e-05 (rank : 829)	NC score	0.643298 (rank : 744)
Query Neighborhood Hits	1959	Target Neighborhood Hits	831	Shared Neighborhood Hits	784
SwissProt Accessions	P08581, O60366, Q12875, Q9UDX7, Q9UPL8	Gene names	MET
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

PINK1_MOUSE
θ value	5.44631e-05 (rank : 830)	NC score	0.729894 (rank : 575)
Query Neighborhood Hits	1959	Target Neighborhood Hits	726	Shared Neighborhood Hits	712
SwissProt Accessions	Q99MQ3, Q7TMZ3, Q811I8, Q91XU5	Gene names	Pink1
Domain Architecture
Description	Serine/threonine-protein kinase PINK1, mitochondrial precursor (EC 2.7.11.1) (PTEN-induced putative kinase protein 1) (BRPK).

VRK1_HUMAN
θ value	5.44631e-05 (rank : 831)	NC score	0.481884 (rank : 820)
Query Neighborhood Hits	1959	Target Neighborhood Hits	584	Shared Neighborhood Hits	573
SwissProt Accessions	Q99986	Gene names	VRK1
Domain Architecture
Description	Serine/threonine-protein kinase VRK1 (EC 2.7.11.1) (Vaccinia-related kinase 1).

VSIG2_HUMAN
θ value	5.44631e-05 (rank : 832)	NC score	0.274653 (rank : 976)
Query Neighborhood Hits	1959	Target Neighborhood Hits	321	Shared Neighborhood Hits	229
SwissProt Accessions	Q96IQ7, O95791, Q9NX42	Gene names	VSIG2, CTH, CTXL
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 2 precursor (CT- like protein) (Cortical thymocyte-like protein).

EPHA8_HUMAN
θ value	7.1131e-05 (rank : 833)	NC score	0.661064 (rank : 705)
Query Neighborhood Hits	1959	Target Neighborhood Hits	956	Shared Neighborhood Hits	868
SwissProt Accessions	P29322, Q9NUA9, Q9P269	Gene names	EPHA8, EEK, KIAA1459
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3).

FAK2_MOUSE
θ value	7.1131e-05 (rank : 834)	NC score	0.685019 (rank : 649)
Query Neighborhood Hits	1959	Target Neighborhood Hits	851	Shared Neighborhood Hits	793
SwissProt Accessions	Q9QVP9	Gene names	Ptk2b, Fak2, Pyk2, Raftk
Domain Architecture	No domain graphic available
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

LRFN3_MOUSE
θ value	7.1131e-05 (rank : 835)	NC score	0.186811 (rank : 1018)
Query Neighborhood Hits	1959	Target Neighborhood Hits	455	Shared Neighborhood Hits	220
SwissProt Accessions	Q8BLY3	Gene names	Lrfn3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 3 precursor.

RIPK3_HUMAN
θ value	7.1131e-05 (rank : 836)	NC score	0.750845 (rank : 551)
Query Neighborhood Hits	1959	Target Neighborhood Hits	828	Shared Neighborhood Hits	797
SwissProt Accessions	Q9Y572	Gene names	RIPK3, RIP3
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3).

EPHA3_MOUSE
θ value	9.29e-05 (rank : 837)	NC score	0.666083 (rank : 689)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1009	Shared Neighborhood Hits	890
SwissProt Accessions	P29319	Gene names	Epha3, Etk1, Mek4, Tyro4
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (MEK4).

ERBB3_MOUSE
θ value	9.29e-05 (rank : 838)	NC score	0.621587 (rank : 765)
Query Neighborhood Hits	1959	Target Neighborhood Hits	898	Shared Neighborhood Hits	770
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

KSR1_HUMAN
θ value	9.29e-05 (rank : 839)	NC score	0.711990 (rank : 601)
Query Neighborhood Hits	1959	Target Neighborhood Hits	867	Shared Neighborhood Hits	794
SwissProt Accessions	Q8IVT5, Q13476	Gene names	KSR1, KSR
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras).

KSR2_HUMAN
θ value	9.29e-05 (rank : 840)	NC score	0.747382 (rank : 556)
Query Neighborhood Hits	1959	Target Neighborhood Hits	920	Shared Neighborhood Hits	843
SwissProt Accessions	Q6VAB6, Q8N775	Gene names	KSR2
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-2 (hKSR2).

SIGL8_HUMAN
θ value	9.29e-05 (rank : 841)	NC score	0.192024 (rank : 1012)
Query Neighborhood Hits	1959	Target Neighborhood Hits	252	Shared Neighborhood Hits	216
SwissProt Accessions	Q9NYZ4, Q7Z728	Gene names	SIGLEC8, SAF2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 8 precursor (Siglec-8) (Sialoadhesin family member 2) (SAF-2) (CDw329 antigen).

TIE1_HUMAN
θ value	9.29e-05 (rank : 842)	NC score	0.672828 (rank : 673)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1241	Shared Neighborhood Hits	909
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TIE1_MOUSE
θ value	9.29e-05 (rank : 843)	NC score	0.677919 (rank : 661)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1266	Shared Neighborhood Hits	923
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

ABL1_HUMAN
θ value	0.000121331 (rank : 844)	NC score	0.688588 (rank : 638)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1220	Shared Neighborhood Hits	913
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

FAK2_HUMAN
θ value	0.000121331 (rank : 845)	NC score	0.680244 (rank : 656)
Query Neighborhood Hits	1959	Target Neighborhood Hits	847	Shared Neighborhood Hits	790
SwissProt Accessions	Q14289, Q13475, Q14290, Q16709	Gene names	PTK2B, FAK2, PYK2, RAFTK
Domain Architecture
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

ICAM5_HUMAN
θ value	0.000121331 (rank : 846)	NC score	0.290820 (rank : 949)
Query Neighborhood Hits	1959	Target Neighborhood Hits	276	Shared Neighborhood Hits	232
SwissProt Accessions	Q9UMF0, Q9Y6F3	Gene names	ICAM5, TLCN, TLN
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

IGF1R_HUMAN
θ value	0.000121331 (rank : 847)	NC score	0.625330 (rank : 762)
Query Neighborhood Hits	1959	Target Neighborhood Hits	977	Shared Neighborhood Hits	818
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

JAM2_HUMAN
θ value	0.000121331 (rank : 848)	NC score	0.284369 (rank : 959)
Query Neighborhood Hits	1959	Target Neighborhood Hits	304	Shared Neighborhood Hits	246
SwissProt Accessions	P57087, Q6UXG6, Q6YNC1	Gene names	JAM2, C21orf43, VEJAM
Domain Architecture
Description	Junctional adhesion molecule B precursor (JAM-B) (Junctional adhesion molecule 2) (Vascular endothelial junction-associated molecule) (VE- JAM) (CD322 antigen).

MAG_HUMAN
θ value	0.000121331 (rank : 849)	NC score	0.330725 (rank : 922)
Query Neighborhood Hits	1959	Target Neighborhood Hits	278	Shared Neighborhood Hits	244
SwissProt Accessions	P20916	Gene names	MAG
Domain Architecture
Description	Myelin-associated glycoprotein precursor (Siglec-4a).

RPKL1_HUMAN
θ value	0.000121331 (rank : 850)	NC score	0.692880 (rank : 631)
Query Neighborhood Hits	1959	Target Neighborhood Hits	708	Shared Neighborhood Hits	669
SwissProt Accessions	Q9Y6S9, Q69YT9, Q6ZMQ6, Q96NR9, Q9BSU9	Gene names	RPS6KL1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase-like 1 (EC 2.7.11.1).

AATK_HUMAN
θ value	0.000158464 (rank : 851)	NC score	0.644918 (rank : 737)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1243	Shared Neighborhood Hits	950
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

ABL1_MOUSE
θ value	0.000158464 (rank : 852)	NC score	0.690194 (rank : 633)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1178	Shared Neighborhood Hits	899
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

CSF1R_HUMAN
θ value	0.000158464 (rank : 853)	NC score	0.616946 (rank : 768)
Query Neighborhood Hits	1959	Target Neighborhood Hits	943	Shared Neighborhood Hits	901
SwissProt Accessions	P07333, Q6LDW5, Q6LDY4	Gene names	CSF1R, FMS
Domain Architecture
Description	Macrophage colony-stimulating factor 1 receptor precursor (EC 2.7.10.1) (CSF-1-R) (Fms proto-oncogene) (c-fms) (CD115 antigen).

E2AK4_HUMAN
θ value	0.000158464 (rank : 854)	NC score	0.789065 (rank : 477)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1012	Shared Neighborhood Hits	834
SwissProt Accessions	Q9P2K8, Q69YL7, Q6DC97, Q96GN6, Q9H5K1, Q9NSQ3, Q9NSZ5, Q9UJ56	Gene names	EIF2AK4, GCN2, KIAA1338
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 2-alpha kinase 4 (EC 2.7.11.1) (GCN2-like protein).

IGF1R_MOUSE
θ value	0.000158464 (rank : 855)	NC score	0.627372 (rank : 758)
Query Neighborhood Hits	1959	Target Neighborhood Hits	973	Shared Neighborhood Hits	816
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

JPH2_MOUSE
θ value	0.000158464 (rank : 856)	NC score	0.033653 (rank : 1485)
Query Neighborhood Hits	1959	Target Neighborhood Hits	279	Shared Neighborhood Hits	121
SwissProt Accessions	Q9ET78, Q9ET79	Gene names	Jph2, Jp2
Domain Architecture	No domain graphic available
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

KSR1_MOUSE
θ value	0.000158464 (rank : 857)	NC score	0.721060 (rank : 589)
Query Neighborhood Hits	1959	Target Neighborhood Hits	870	Shared Neighborhood Hits	807
SwissProt Accessions	Q61097, Q61648, Q78DX8	Gene names	Ksr1, Ksr
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras) (mKSR1) (Hb protein).

MUC18_MOUSE
θ value	0.000158464 (rank : 858)	NC score	0.288606 (rank : 956)
Query Neighborhood Hits	1959	Target Neighborhood Hits	292	Shared Neighborhood Hits	221
SwissProt Accessions	Q8R2Y2, Q9EPF1, Q9ESS7, Q9JHQ2, Q9JHQ3	Gene names	Mcam, Muc18
Domain Architecture	No domain graphic available
Description	Cell surface glycoprotein MUC18 precursor (Melanoma-associated antigen MUC18) (Melanoma cell adhesion molecule) (Gicerin).

SON_HUMAN
θ value	0.000158464 (rank : 859)	NC score	0.088215 (rank : 1146)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1568	Shared Neighborhood Hits	526
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

TYRO3_HUMAN
θ value	0.000158464 (rank : 860)	NC score	0.705999 (rank : 611)
Query Neighborhood Hits	1959	Target Neighborhood Hits	995	Shared Neighborhood Hits	939
SwissProt Accessions	Q06418, O14953, Q86VR3	Gene names	TYRO3, BYK, DTK, RSE, SKY
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine- protein kinase DTK) (Protein-tyrosine kinase byk).

TYRO3_MOUSE
θ value	0.000158464 (rank : 861)	NC score	0.704737 (rank : 612)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1007	Shared Neighborhood Hits	944
SwissProt Accessions	P55144, O09070, O09080, P70285, Q60752, Q62482, Q62483, Q62484, Q78E85, Q78E87	Gene names	Tyro3, Dtk, Rse
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase DTK) (TK19-2) (Etk2/tyro3).

ERBB3_HUMAN
θ value	0.00020696 (rank : 862)	NC score	0.617812 (rank : 767)
Query Neighborhood Hits	1959	Target Neighborhood Hits	918	Shared Neighborhood Hits	768
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

LCP2_HUMAN
θ value	0.00020696 (rank : 863)	NC score	0.083660 (rank : 1159)
Query Neighborhood Hits	1959	Target Neighborhood Hits	531	Shared Neighborhood Hits	246
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

LRFN4_HUMAN
θ value	0.00020696 (rank : 864)	NC score	0.191644 (rank : 1014)
Query Neighborhood Hits	1959	Target Neighborhood Hits	462	Shared Neighborhood Hits	222
SwissProt Accessions	Q6PJG9, Q9BWJ0	Gene names	LRFN4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursor.

LRFN5_MOUSE
θ value	0.00020696 (rank : 865)	NC score	0.176106 (rank : 1026)
Query Neighborhood Hits	1959	Target Neighborhood Hits	472	Shared Neighborhood Hits	227
SwissProt Accessions	Q8BXA0, Q8BJH4, Q8BZL0	Gene names	Lrfn5
Domain Architecture
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 5 precursor.

NCOA6_HUMAN
θ value	0.00020696 (rank : 866)	NC score	0.087264 (rank : 1147)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1202	Shared Neighborhood Hits	443
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

RAGE_HUMAN
θ value	0.00020696 (rank : 867)	NC score	0.318238 (rank : 929)
Query Neighborhood Hits	1959	Target Neighborhood Hits	269	Shared Neighborhood Hits	234
SwissProt Accessions	Q15109, Q15279, Q9H2X7, Q9Y3R3	Gene names	AGER, RAGE
Domain Architecture
Description	Advanced glycosylation end product-specific receptor precursor (Receptor for advanced glycosylation end products).

AVR2A_HUMAN
θ value	0.000270298 (rank : 868)	NC score	0.643399 (rank : 743)
Query Neighborhood Hits	1959	Target Neighborhood Hits	767	Shared Neighborhood Hits	751
SwissProt Accessions	P27037, Q53TH4, Q6NWV2, Q92474	Gene names	ACVR2A, ACVR2
Domain Architecture
Description	Activin receptor type 2A precursor (EC 2.7.11.30) (Activin receptor type IIA) (ACTR-IIA) (ACTRIIA).

AVR2A_MOUSE
θ value	0.000270298 (rank : 869)	NC score	0.643413 (rank : 742)
Query Neighborhood Hits	1959	Target Neighborhood Hits	767	Shared Neighborhood Hits	751
SwissProt Accessions	P27038	Gene names	Acvr2a, Acvr2
Domain Architecture
Description	Activin receptor type 2A precursor (EC 2.7.11.30) (Activin receptor type IIA) (ACTR-IIA).

BUB1_MOUSE
θ value	0.000270298 (rank : 870)	NC score	0.576581 (rank : 799)
Query Neighborhood Hits	1959	Target Neighborhood Hits	583	Shared Neighborhood Hits	538
SwissProt Accessions	O08901, O09007	Gene names	Bub1
Domain Architecture
Description	Mitotic checkpoint serine/threonine-protein kinase BUB1 (EC 2.7.11.1) (MBUB1) (BUB1A).

CI096_HUMAN
θ value	0.000270298 (rank : 871)	NC score	0.793801 (rank : 466)
Query Neighborhood Hits	1959	Target Neighborhood Hits	821	Shared Neighborhood Hits	793
SwissProt Accessions	Q8NE28, Q5T8U8	Gene names	C9orf96
Domain Architecture	No domain graphic available
Description	Protein kinase-like protein C9orf96.

FLT3_MOUSE
θ value	0.000270298 (rank : 872)	NC score	0.612483 (rank : 771)
Query Neighborhood Hits	1959	Target Neighborhood Hits	847	Shared Neighborhood Hits	826
SwissProt Accessions	Q00342	Gene names	Flt3, Flk-2, Flt-3
Domain Architecture
Description	FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor flk-2) (Fetal liver kinase 2) (Tyrosine-protein kinase FLT3) (CD135 antigen).

FSTL5_HUMAN
θ value	0.000270298 (rank : 873)	NC score	0.310431 (rank : 938)
Query Neighborhood Hits	1959	Target Neighborhood Hits	347	Shared Neighborhood Hits	258
SwissProt Accessions	Q8N475, Q9NSW7, Q9ULF7	Gene names	FSTL5, KIAA1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5).

ICAM5_MOUSE
θ value	0.000270298 (rank : 874)	NC score	0.299903 (rank : 944)
Query Neighborhood Hits	1959	Target Neighborhood Hits	308	Shared Neighborhood Hits	241
SwissProt Accessions	Q60625	Gene names	Icam5, Tlcn
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

KAZD1_MOUSE
θ value	0.000270298 (rank : 875)	NC score	0.282842 (rank : 962)
Query Neighborhood Hits	1959	Target Neighborhood Hits	281	Shared Neighborhood Hits	201
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).

MAG_MOUSE
θ value	0.000270298 (rank : 876)	NC score	0.331375 (rank : 921)
Query Neighborhood Hits	1959	Target Neighborhood Hits	271	Shared Neighborhood Hits	243
SwissProt Accessions	P20917, P16880	Gene names	Mag
Domain Architecture
Description	Myelin-associated glycoprotein precursor (Siglec-4a).

CUTL1_MOUSE
θ value	0.00035302 (rank : 877)	NC score	0.026573 (rank : 1535)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1620	Shared Neighborhood Hits	279
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

FSTL5_MOUSE
θ value	0.00035302 (rank : 878)	NC score	0.305883 (rank : 941)
Query Neighborhood Hits	1959	Target Neighborhood Hits	355	Shared Neighborhood Hits	255
SwissProt Accessions	Q8BFR2, Q80TG3, Q8C4T3	Gene names	Fstl5, Kiaa1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5) (m- D/Bsp120I 1-2).

SIGL5_HUMAN
θ value	0.00035302 (rank : 879)	NC score	0.191847 (rank : 1013)
Query Neighborhood Hits	1959	Target Neighborhood Hits	246	Shared Neighborhood Hits	193
SwissProt Accessions	O15389	Gene names	SIGLEC5, CD33L2, OBBP2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 5 precursor (Siglec-5) (Obesity- binding protein 2) (OB-binding protein 2) (OB-BP2) (CD33 antigen-like 2) (CD170 antigen).

E2AK4_MOUSE
θ value	0.000461057 (rank : 880)	NC score	0.785581 (rank : 489)
Query Neighborhood Hits	1959	Target Neighborhood Hits	984	Shared Neighborhood Hits	832
SwissProt Accessions	Q9QZ05, Q6GQT4, Q6ZPT5, Q8C5S0, Q8CIF5, Q9CT30, Q9CUV9, Q9ESB6, Q9ESB7, Q9ESB8	Gene names	Eif2ak4, Gcn2, Kiaa1338
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 2-alpha kinase 4 (EC 2.7.11.1) (GCN2-like protein) (mGCN2).

FLT3_HUMAN
θ value	0.000461057 (rank : 881)	NC score	0.607656 (rank : 777)
Query Neighborhood Hits	1959	Target Neighborhood Hits	843	Shared Neighborhood Hits	817
SwissProt Accessions	P36888, Q13414	Gene names	FLT3, STK1
Domain Architecture
Description	FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor FLT3) (Stem cell tyrosine kinase 1) (STK-1) (CD135 antigen).

IRPL2_HUMAN
θ value	0.000461057 (rank : 882)	NC score	0.165890 (rank : 1036)
Query Neighborhood Hits	1959	Target Neighborhood Hits	194	Shared Neighborhood Hits	140
SwissProt Accessions	Q9NP60, Q9NZN0	Gene names	IL1RAPL2, IL1R9
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 2 precursor (IL1RAPL-2-related protein) (Interleukin-1 receptor 9) (IL-1R9) (IL-1 receptor accessory protein-like 2) (Three immunoglobulin domain- containing IL-1 receptor-related 1) (TIGIRR-1).

IRPL2_MOUSE
θ value	0.000461057 (rank : 883)	NC score	0.163579 (rank : 1040)
Query Neighborhood Hits	1959	Target Neighborhood Hits	195	Shared Neighborhood Hits	138
SwissProt Accessions	Q9ERS6, Q9ER66	Gene names	Il1rapl2
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 2 precursor (IL1RAPL-2-related protein) (TIGIRR-1).

LRC24_HUMAN
θ value	0.000461057 (rank : 884)	NC score	0.136611 (rank : 1072)
Query Neighborhood Hits	1959	Target Neighborhood Hits	404	Shared Neighborhood Hits	193
SwissProt Accessions	Q50LG9	Gene names	LRRC24
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 24 precursor.

LRFN5_HUMAN
θ value	0.000461057 (rank : 885)	NC score	0.172332 (rank : 1033)
Query Neighborhood Hits	1959	Target Neighborhood Hits	464	Shared Neighborhood Hits	223
SwissProt Accessions	Q96NI6, Q86XL2	Gene names	LRFN5, C14orf146
Domain Architecture
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 5 precursor.

TTBK1_HUMAN
θ value	0.000461057 (rank : 886)	NC score	0.685869 (rank : 646)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1058	Shared Neighborhood Hits	832
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

TTBK2_HUMAN
θ value	0.000461057 (rank : 887)	NC score	0.672277 (rank : 676)
Query Neighborhood Hits	1959	Target Neighborhood Hits	822	Shared Neighborhood Hits	740
SwissProt Accessions	Q6IQ55, O94932, Q6ZN52, Q8IVV1	Gene names	TTBK2, KIAA0847
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 2 (EC 2.7.11.1).

ANKK1_HUMAN
θ value	0.000602161 (rank : 888)	NC score	0.582202 (rank : 797)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1075	Shared Neighborhood Hits	785
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

K1802_MOUSE
θ value	0.000602161 (rank : 889)	NC score	0.056845 (rank : 1304)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1596	Shared Neighborhood Hits	449
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

KC1AL_HUMAN
θ value	0.000602161 (rank : 890)	NC score	0.662683 (rank : 702)
Query Neighborhood Hits	1959	Target Neighborhood Hits	734	Shared Neighborhood Hits	723
SwissProt Accessions	Q8N752	Gene names	CSNK1A1L
Domain Architecture
Description	Casein kinase I isoform alpha-like (EC 2.7.11.1) (CKI-alpha-like) (CK1).

KIT_HUMAN
θ value	0.000602161 (rank : 891)	NC score	0.644559 (rank : 740)
Query Neighborhood Hits	1959	Target Neighborhood Hits	953	Shared Neighborhood Hits	907
SwissProt Accessions	P10721, Q9UM99	Gene names	KIT
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

MDC1_HUMAN
θ value	0.000602161 (rank : 892)	NC score	0.105078 (rank : 1120)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1446	Shared Neighborhood Hits	467
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

OGFR_HUMAN
θ value	0.000602161 (rank : 893)	NC score	0.095065 (rank : 1136)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1582	Shared Neighborhood Hits	543
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

PRRT3_HUMAN
θ value	0.000602161 (rank : 894)	NC score	0.101223 (rank : 1127)
Query Neighborhood Hits	1959	Target Neighborhood Hits	998	Shared Neighborhood Hits	433
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

SAPS1_HUMAN
θ value	0.000602161 (rank : 895)	NC score	0.062455 (rank : 1270)
Query Neighborhood Hits	1959	Target Neighborhood Hits	704	Shared Neighborhood Hits	330
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

AKAP2_MOUSE
θ value	0.000786445 (rank : 896)	NC score	0.048828 (rank : 1372)
Query Neighborhood Hits	1959	Target Neighborhood Hits	385	Shared Neighborhood Hits	124
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

ANKK1_MOUSE
θ value	0.000786445 (rank : 897)	NC score	0.593376 (rank : 789)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1072	Shared Neighborhood Hits	790
SwissProt Accessions	Q8BZ25	Gene names	Ankk1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1).

EGFR_HUMAN
θ value	0.000786445 (rank : 898)	NC score	0.655090 (rank : 725)
Query Neighborhood Hits	1959	Target Neighborhood Hits	939	Shared Neighborhood Hits	799
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

EGFR_MOUSE
θ value	0.000786445 (rank : 899)	NC score	0.655494 (rank : 723)
Query Neighborhood Hits	1959	Target Neighborhood Hits	927	Shared Neighborhood Hits	805
SwissProt Accessions	Q01279	Gene names	Egfr
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1).

EPHA6_HUMAN
θ value	0.000786445 (rank : 900)	NC score	0.607415 (rank : 778)
Query Neighborhood Hits	1959	Target Neighborhood Hits	959	Shared Neighborhood Hits	845
SwissProt Accessions	Q9UF33	Gene names	EPHA6, EHK2
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

EPHA6_MOUSE
θ value	0.000786445 (rank : 901)	NC score	0.609032 (rank : 775)
Query Neighborhood Hits	1959	Target Neighborhood Hits	946	Shared Neighborhood Hits	839
SwissProt Accessions	Q62413, Q8CCN2	Gene names	Epha6, Ehk-2, Ehk2
Domain Architecture
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

INSRR_HUMAN
θ value	0.000786445 (rank : 902)	NC score	0.626913 (rank : 759)
Query Neighborhood Hits	1959	Target Neighborhood Hits	950	Shared Neighborhood Hits	808
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

KC1D_HUMAN
θ value	0.000786445 (rank : 903)	NC score	0.660991 (rank : 707)
Query Neighborhood Hits	1959	Target Neighborhood Hits	737	Shared Neighborhood Hits	723
SwissProt Accessions	P48730, Q96KZ6, Q9BTN5	Gene names	CSNK1D
Domain Architecture
Description	Casein kinase I isoform delta (EC 2.7.11.1) (CKI-delta) (CKId).

KC1D_MOUSE
θ value	0.000786445 (rank : 904)	NC score	0.660999 (rank : 706)
Query Neighborhood Hits	1959	Target Neighborhood Hits	737	Shared Neighborhood Hits	723
SwissProt Accessions	Q9DC28, Q3TZK2, Q99KK4	Gene names	Csnk1d
Domain Architecture
Description	Casein kinase I isoform delta (EC 2.7.11.1) (CKI-delta) (CKId).

KC1E_HUMAN
θ value	0.000786445 (rank : 905)	NC score	0.657813 (rank : 716)
Query Neighborhood Hits	1959	Target Neighborhood Hits	732	Shared Neighborhood Hits	721
SwissProt Accessions	P49674	Gene names	CSNK1E
Domain Architecture
Description	Casein kinase I isoform epsilon (EC 2.7.11.1) (CKI-epsilon) (CKIe).

KC1E_MOUSE
θ value	0.000786445 (rank : 906)	NC score	0.657766 (rank : 717)
Query Neighborhood Hits	1959	Target Neighborhood Hits	728	Shared Neighborhood Hits	720
SwissProt Accessions	Q9JMK2, Q8R389	Gene names	Csnk1e
Domain Architecture
Description	Casein kinase I isoform epsilon (EC 2.7.11.1) (CKI-epsilon) (CKIe).

LRFN2_HUMAN
θ value	0.000786445 (rank : 907)	NC score	0.188505 (rank : 1016)
Query Neighborhood Hits	1959	Target Neighborhood Hits	450	Shared Neighborhood Hits	220
SwissProt Accessions	Q9ULH4, Q5SYP9	Gene names	LRFN2, KIAA1246
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 2 precursor.

LRFN2_MOUSE
θ value	0.000786445 (rank : 908)	NC score	0.188237 (rank : 1017)
Query Neighborhood Hits	1959	Target Neighborhood Hits	450	Shared Neighborhood Hits	220
SwissProt Accessions	Q80TG9, Q9CYK3	Gene names	Lrfn2, Kiaa1246
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 2 precursor.

MDC1_MOUSE
θ value	0.000786445 (rank : 909)	NC score	0.099899 (rank : 1129)
Query Neighborhood Hits	1959	Target Neighborhood Hits	998	Shared Neighborhood Hits	405
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

RGS3_MOUSE
θ value	0.000786445 (rank : 910)	NC score	0.086747 (rank : 1153)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1621	Shared Neighborhood Hits	557
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SIG12_HUMAN
θ value	0.000786445 (rank : 911)	NC score	0.179689 (rank : 1021)
Query Neighborhood Hits	1959	Target Neighborhood Hits	245	Shared Neighborhood Hits	213
SwissProt Accessions	Q96PQ1, Q8IYH7	Gene names	SIGLEC12, SIGLECL1, SLG
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 12 precursor (Siglec-12) (Sialic acid-binding Ig-like lectin-like 1) (Siglec-L1).

SRPK2_HUMAN
θ value	0.000786445 (rank : 912)	NC score	0.538407 (rank : 808)
Query Neighborhood Hits	1959	Target Neighborhood Hits	664	Shared Neighborhood Hits	573
SwissProt Accessions	P78362, O75220, O75221, Q6NUL0, Q6V1X2, Q8IYQ3	Gene names	SRPK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SRPK2 (EC 2.7.11.1) (Serine/arginine- rich protein-specific kinase 2) (SR-protein-specific kinase 2) (SFRS protein kinase 2).

SRPK2_MOUSE
θ value	0.000786445 (rank : 913)	NC score	0.535838 (rank : 813)
Query Neighborhood Hits	1959	Target Neighborhood Hits	765	Shared Neighborhood Hits	587
SwissProt Accessions	O54781, Q8VCD9	Gene names	Srpk2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SRPK2 (EC 2.7.11.1) (Serine/arginine- rich protein-specific kinase 2) (SR-protein-specific kinase 2) (SFRS protein kinase 2).

CIC_HUMAN
θ value	0.00102713 (rank : 914)	NC score	0.062310 (rank : 1273)
Query Neighborhood Hits	1959	Target Neighborhood Hits	992	Shared Neighborhood Hits	395
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

ERBB4_HUMAN
θ value	0.00102713 (rank : 915)	NC score	0.656596 (rank : 720)
Query Neighborhood Hits	1959	Target Neighborhood Hits	910	Shared Neighborhood Hits	797
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

IBP7_HUMAN
θ value	0.00102713 (rank : 916)	NC score	0.246637 (rank : 994)
Query Neighborhood Hits	1959	Target Neighborhood Hits	220	Shared Neighborhood Hits	165
SwissProt Accessions	Q16270, Q07822	Gene names	IGFBP7, MAC25, PSF
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein) (Prostacyclin-stimulating factor) (PGI2-stimulating factor) (IGFBP-rP1).

LRC21_HUMAN
θ value	0.00102713 (rank : 917)	NC score	0.175531 (rank : 1027)
Query Neighborhood Hits	1959	Target Neighborhood Hits	456	Shared Neighborhood Hits	224
SwissProt Accessions	Q9P2V4, Q9Y4N7	Gene names	LRRC21, PAL
Domain Architecture
Description	Leucine-rich repeat-containing protein 21 precursor (Photoreceptor- associated LRR superfamily protein) (Retina-specific protein PAL).

LU_HUMAN
θ value	0.00102713 (rank : 918)	NC score	0.315323 (rank : 932)
Query Neighborhood Hits	1959	Target Neighborhood Hits	283	Shared Neighborhood Hits	232
SwissProt Accessions	P50895, Q86VC7	Gene names	BCAM, LU, MSK19
Domain Architecture
Description	Lutheran blood group glycoprotein precursor (B-CAM cell surface glycoprotein) (Auberger B antigen) (F8/G253 antigen) (CD239 antigen).

RIPK3_MOUSE
θ value	0.00102713 (rank : 919)	NC score	0.754548 (rank : 545)
Query Neighborhood Hits	1959	Target Neighborhood Hits	867	Shared Neighborhood Hits	814
SwissProt Accessions	Q9QZL0	Gene names	Ripk3, Rip3
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (mRIP3).

INSRR_MOUSE
θ value	0.00134147 (rank : 920)	NC score	0.629775 (rank : 755)
Query Neighborhood Hits	1959	Target Neighborhood Hits	961	Shared Neighborhood Hits	807
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

IRPL1_HUMAN
θ value	0.00134147 (rank : 921)	NC score	0.157460 (rank : 1045)
Query Neighborhood Hits	1959	Target Neighborhood Hits	196	Shared Neighborhood Hits	152
SwissProt Accessions	Q9NZN1, Q9UJ53	Gene names	IL1RAPL1, OPHN4
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 1 precursor (IL1RAPL-1) (Oligophrenin-4) (Three immunoglobulin domain-containing IL-1 receptor-related 2) (TIGIRR-2).

IRPL1_MOUSE
θ value	0.00134147 (rank : 922)	NC score	0.162031 (rank : 1041)
Query Neighborhood Hits	1959	Target Neighborhood Hits	186	Shared Neighborhood Hits	149
SwissProt Accessions	P59823	Gene names	Il1rapl1
Domain Architecture	No domain graphic available
Description	X-linked interleukin-1 receptor accessory protein-like 1 precursor (IL1RAPL-1).

JAM2_MOUSE
θ value	0.00134147 (rank : 923)	NC score	0.275293 (rank : 975)
Query Neighborhood Hits	1959	Target Neighborhood Hits	292	Shared Neighborhood Hits	234
SwissProt Accessions	Q9JI59, Q8C5K9, Q8CE95	Gene names	Jam2, Vejam
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule B precursor (JAM-B) (Junctional adhesion molecule 2) (Vascular endothelial junction-associated molecule) (VE- JAM) (CD322 antigen).

KC1A_HUMAN
θ value	0.00134147 (rank : 924)	NC score	0.665438 (rank : 691)
Query Neighborhood Hits	1959	Target Neighborhood Hits	728	Shared Neighborhood Hits	723
SwissProt Accessions	P48729, Q96HD2	Gene names	CSNK1A1
Domain Architecture
Description	Casein kinase I isoform alpha (EC 2.7.11.1) (CKI-alpha) (CK1).

KC1A_MOUSE
θ value	0.00134147 (rank : 925)	NC score	0.665438 (rank : 692)
Query Neighborhood Hits	1959	Target Neighborhood Hits	728	Shared Neighborhood Hits	723
SwissProt Accessions	Q8BK63, Q3UIL0, Q64506, Q80XI2, Q99LY3	Gene names	Csnk1a1
Domain Architecture
Description	Casein kinase I isoform alpha (EC 2.7.11.1) (CKI-alpha) (CK1).

LRC21_MOUSE
θ value	0.00134147 (rank : 926)	NC score	0.176160 (rank : 1025)
Query Neighborhood Hits	1959	Target Neighborhood Hits	462	Shared Neighborhood Hits	229
SwissProt Accessions	Q8K099, Q8BXN3	Gene names	Lrrc21, Pal
Domain Architecture
Description	Leucine-rich repeat-containing protein 21 precursor (Photoreceptor- associated LRR superfamily protein) (Retina-specific protein PAL).

MAP1B_HUMAN
θ value	0.00134147 (rank : 927)	NC score	0.050610 (rank : 1349)
Query Neighborhood Hits	1959	Target Neighborhood Hits	903	Shared Neighborhood Hits	204
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

MERTK_HUMAN
θ value	0.00134147 (rank : 928)	NC score	0.667708 (rank : 685)
Query Neighborhood Hits	1959	Target Neighborhood Hits	988	Shared Neighborhood Hits	922
SwissProt Accessions	Q12866, Q9HBB4	Gene names	MERTK, MER
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

T22D4_HUMAN
θ value	0.00134147 (rank : 929)	NC score	0.064493 (rank : 1257)
Query Neighborhood Hits	1959	Target Neighborhood Hits	403	Shared Neighborhood Hits	207
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

TTBK2_MOUSE
θ value	0.00134147 (rank : 930)	NC score	0.668696 (rank : 684)
Query Neighborhood Hits	1959	Target Neighborhood Hits	811	Shared Neighborhood Hits	725
SwissProt Accessions	Q3UVR3, Q3TSR6, Q3UFW0, Q571D1, Q8BKA4, Q924U8	Gene names	Ttbk2, Kiaa0847, Ttbk1
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 2.

VRK2_HUMAN
θ value	0.00134147 (rank : 931)	NC score	0.480565 (rank : 821)
Query Neighborhood Hits	1959	Target Neighborhood Hits	582	Shared Neighborhood Hits	559
SwissProt Accessions	Q86Y07, Q49AK9, Q53EU9, Q86Y08, Q86Y09, Q86Y10, Q86Y11, Q86Y12, Q8IXI5, Q99987	Gene names	VRK2
Domain Architecture
Description	Serine/threonine-protein kinase VRK2 (EC 2.7.11.1) (Vaccinia-related kinase 2).

DDR1_HUMAN
θ value	0.00175202 (rank : 932)	NC score	0.609797 (rank : 773)
Query Neighborhood Hits	1959	Target Neighborhood Hits	819	Shared Neighborhood Hits	762
SwissProt Accessions	Q08345, Q14196, Q16562, Q5ST12, Q9UD37	Gene names	DDR1, CAK, EDDR1, RTK6, TRKE
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (TRK E) (Protein-tyrosine kinase RTK 6) (HGK2) (CD167a antigen).

LRRN5_HUMAN
θ value	0.00175202 (rank : 933)	NC score	0.146128 (rank : 1061)
Query Neighborhood Hits	1959	Target Neighborhood Hits	493	Shared Neighborhood Hits	240
SwissProt Accessions	O75325, Q5T0Y0, Q6UXM0, Q8N182	Gene names	LRRN5, GAC1, LRRN2
Domain Architecture
Description	Leucine-rich repeats neuronal protein 5 precursor (Glioma amplified on chromosome 1 protein).

MAGE1_HUMAN
θ value	0.00175202 (rank : 934)	NC score	0.069434 (rank : 1220)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1389	Shared Neighborhood Hits	486
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MILK1_MOUSE
θ value	0.00175202 (rank : 935)	NC score	0.049434 (rank : 1368)
Query Neighborhood Hits	1959	Target Neighborhood Hits	788	Shared Neighborhood Hits	324
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

NRBP_MOUSE
θ value	0.00175202 (rank : 936)	NC score	0.468910 (rank : 823)
Query Neighborhood Hits	1959	Target Neighborhood Hits	442	Shared Neighborhood Hits	415
SwissProt Accessions	Q99J45, Q8BL77	Gene names	Nrbp1, Madm, Nrbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor-binding protein (MLF1 adapter molecule) (HLS7- interacting protein kinase).

TNI3K_HUMAN
θ value	0.00175202 (rank : 937)	NC score	0.643286 (rank : 745)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1084	Shared Neighborhood Hits	793
SwissProt Accessions	Q59H18, Q49AR1, Q6MZS9, Q9Y2V6	Gene names	TNNI3K, CARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

UFO_MOUSE
θ value	0.00175202 (rank : 938)	NC score	0.678571 (rank : 660)
Query Neighborhood Hits	1959	Target Neighborhood Hits	988	Shared Neighborhood Hits	896
SwissProt Accessions	Q00993	Gene names	Axl, Ark, Ufo
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (Adhesion-related kinase).

CDC7_MOUSE
θ value	0.00228821 (rank : 939)	NC score	0.676770 (rank : 664)
Query Neighborhood Hits	1959	Target Neighborhood Hits	641	Shared Neighborhood Hits	629
SwissProt Accessions	Q9Z0H0, Q9Z2Y7	Gene names	Cdc7, Cdc7l1
Domain Architecture
Description	Cell division cycle 7-related protein kinase (EC 2.7.11.1) (CDC7- related kinase) (muCdc7).

CEAM1_HUMAN
θ value	0.00228821 (rank : 940)	NC score	0.239004 (rank : 996)
Query Neighborhood Hits	1959	Target Neighborhood Hits	348	Shared Neighborhood Hits	237
SwissProt Accessions	P13688, O60430, Q13858, Q15600, Q9UQV9	Gene names	CEACAM1, BGP, BGP1
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 1 precursor (Biliary glycoprotein 1) (BGP-1) (CD66 antigen) (CD66a antigen).

CILP2_HUMAN
θ value	0.00228821 (rank : 941)	NC score	0.185640 (rank : 1019)
Query Neighborhood Hits	1959	Target Neighborhood Hits	307	Shared Neighborhood Hits	190
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

ILRL1_HUMAN
θ value	0.00228821 (rank : 942)	NC score	0.124023 (rank : 1087)
Query Neighborhood Hits	1959	Target Neighborhood Hits	167	Shared Neighborhood Hits	122
SwissProt Accessions	Q01638, Q53TU7, Q8NEJ3, Q9ULV7, Q9UQ44	Gene names	IL1RL1, DER4, ST2, T1
Domain Architecture
Description	Interleukin-1 receptor-like 1 precursor (ST2 protein).

JAM3_HUMAN
θ value	0.00228821 (rank : 943)	NC score	0.290752 (rank : 950)
Query Neighborhood Hits	1959	Target Neighborhood Hits	271	Shared Neighborhood Hits	226
SwissProt Accessions	Q9BX67, Q8WWL8, Q96FL1	Gene names	JAM3
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule C precursor (JAM-C) (Junctional adhesion molecule 3) (JAM-3) (JAM-2).

KIRR1_HUMAN
θ value	0.00228821 (rank : 944)	NC score	0.293934 (rank : 948)
Query Neighborhood Hits	1959	Target Neighborhood Hits	401	Shared Neighborhood Hits	248
SwissProt Accessions	Q96J84, Q5XKC6, Q7Z696, Q7Z7N8, Q8TB15, Q9H9N1, Q9NVA5	Gene names	KIRREL, NEPH1
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 1 precursor (Kin of irregular chiasm-like protein 1) (Nephrin-like protein 1).

KIRR1_MOUSE
θ value	0.00228821 (rank : 945)	NC score	0.290068 (rank : 952)
Query Neighborhood Hits	1959	Target Neighborhood Hits	403	Shared Neighborhood Hits	245
SwissProt Accessions	Q80W68, Q8CIJ4, Q8CJ59, Q923L4	Gene names	Kirrel1, Kirrel, Neph1
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 1 precursor (Kin of irregular chiasm-like protein 1) (Nephrin-like protein 1).

NGL1_HUMAN
θ value	0.00228821 (rank : 946)	NC score	0.124757 (rank : 1084)
Query Neighborhood Hits	1959	Target Neighborhood Hits	511	Shared Neighborhood Hits	229
SwissProt Accessions	Q9HCJ2, Q7L0N3	Gene names	LRRC4C, KIAA1580, NGL1
Domain Architecture	No domain graphic available
Description	Netrin-G1 ligand precursor (NGL-1) (Leucine-rich repeat-containing protein 4C).

RGS3_HUMAN
θ value	0.00228821 (rank : 947)	NC score	0.074303 (rank : 1194)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1375	Shared Neighborhood Hits	452
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

RPKL1_MOUSE
θ value	0.00228821 (rank : 948)	NC score	0.694953 (rank : 628)
Query Neighborhood Hits	1959	Target Neighborhood Hits	704	Shared Neighborhood Hits	679
SwissProt Accessions	Q8R2S1, Q8R1D4	Gene names	Rps6kl1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase-like 1 (EC 2.7.11.1).

TULP4_HUMAN
θ value	0.00228821 (rank : 949)	NC score	0.041619 (rank : 1426)
Query Neighborhood Hits	1959	Target Neighborhood Hits	426	Shared Neighborhood Hits	147
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

BSN_MOUSE
θ value	0.00298849 (rank : 950)	NC score	0.099022 (rank : 1132)
Query Neighborhood Hits	1959	Target Neighborhood Hits	2057	Shared Neighborhood Hits	624
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

DDR1_MOUSE
θ value	0.00298849 (rank : 951)	NC score	0.611934 (rank : 772)
Query Neighborhood Hits	1959	Target Neighborhood Hits	818	Shared Neighborhood Hits	761
SwissProt Accessions	Q03146	Gene names	Ddr1, Cak, Eddr1, Mpk6
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (Protein-tyrosine kinase MPK-6) (CD167a antigen).

GUC2F_HUMAN
θ value	0.00298849 (rank : 952)	NC score	0.511085 (rank : 816)
Query Neighborhood Hits	1959	Target Neighborhood Hits	740	Shared Neighborhood Hits	668
SwissProt Accessions	P51841, Q9UJF1	Gene names	GUCY2F, GUC2F, RETGC2
Domain Architecture
Description	Retinal guanylyl cyclase 2 precursor (EC 4.6.1.2) (Guanylate cyclase 2F, retinal) (RETGC-2) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2) (Guanylate cyclase F) (GC-F).

IGS4B_HUMAN
θ value	0.00298849 (rank : 953)	NC score	0.270183 (rank : 978)
Query Neighborhood Hits	1959	Target Neighborhood Hits	305	Shared Neighborhood Hits	227
SwissProt Accessions	Q8N126, Q9NVJ5, Q9UJP1	Gene names	IGSF4B, NECL1, SYNCAM3, TSLL1
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 4B precursor (Nectin-like protein 1) (TSLC1-like protein 1) (Synaptic cell adhesion molecule 3) (Brain immunoglobulin receptor).

KIT_MOUSE
θ value	0.00298849 (rank : 954)	NC score	0.644275 (rank : 741)
Query Neighborhood Hits	1959	Target Neighborhood Hits	949	Shared Neighborhood Hits	912
SwissProt Accessions	P05532, Q61415, Q61416, Q61417, Q6LEE9	Gene names	Kit, Sl
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

LRC4B_HUMAN
θ value	0.00298849 (rank : 955)	NC score	0.124008 (rank : 1088)
Query Neighborhood Hits	1959	Target Neighborhood Hits	479	Shared Neighborhood Hits	216
SwissProt Accessions	Q9NT99, Q3ZCQ4, Q58F20	Gene names	LRRC4B, LRIG4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4B precursor.

LRC4B_MOUSE
θ value	0.00298849 (rank : 956)	NC score	0.125156 (rank : 1082)
Query Neighborhood Hits	1959	Target Neighborhood Hits	484	Shared Neighborhood Hits	218
SwissProt Accessions	P0C192	Gene names	Lrrc4b, Lrig4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4B precursor.

NGL1_MOUSE
θ value	0.00298849 (rank : 957)	NC score	0.124716 (rank : 1085)
Query Neighborhood Hits	1959	Target Neighborhood Hits	512	Shared Neighborhood Hits	229
SwissProt Accessions	Q8C031, Q8BGH8	Gene names	Lrrc4c, Ngl1
Domain Architecture	No domain graphic available
Description	Netrin-G1 ligand precursor (NGL-1) (Leucine-rich repeat-containing protein 4C).

NRBP_HUMAN
θ value	0.00298849 (rank : 958)	NC score	0.470572 (rank : 822)
Query Neighborhood Hits	1959	Target Neighborhood Hits	448	Shared Neighborhood Hits	420
SwissProt Accessions	Q9UHY1, Q53FZ5, Q96SU3	Gene names	NRBP1, BCON3, NRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor-binding protein.

SPR1B_MOUSE
θ value	0.00298849 (rank : 959)	NC score	0.068722 (rank : 1226)
Query Neighborhood Hits	1959	Target Neighborhood Hits	395	Shared Neighborhood Hits	189
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

COTE1_HUMAN
θ value	0.00390308 (rank : 960)	NC score	0.028963 (rank : 1519)
Query Neighborhood Hits	1959	Target Neighborhood Hits	40	Shared Neighborhood Hits	12
SwissProt Accessions	P81408	Gene names	C1orf2, COTE1
Domain Architecture	No domain graphic available
Description	Protein COTE1.

EPHAA_HUMAN
θ value	0.00390308 (rank : 961)	NC score	0.553415 (rank : 804)
Query Neighborhood Hits	1959	Target Neighborhood Hits	960	Shared Neighborhood Hits	788
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

GRIN1_HUMAN
θ value	0.00390308 (rank : 962)	NC score	0.068555 (rank : 1228)
Query Neighborhood Hits	1959	Target Neighborhood Hits	681	Shared Neighborhood Hits	274
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

RIPK4_HUMAN
θ value	0.00390308 (rank : 963)	NC score	0.582583 (rank : 796)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1094	Shared Neighborhood Hits	796
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

ROS_HUMAN
θ value	0.00390308 (rank : 964)	NC score	0.665064 (rank : 694)
Query Neighborhood Hits	1959	Target Neighborhood Hits	907	Shared Neighborhood Hits	825
SwissProt Accessions	P08922, Q15368	Gene names	ROS1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ROS precursor (EC 2.7.10.1) (c- ros-1).

SIGL6_HUMAN
θ value	0.00390308 (rank : 965)	NC score	0.175501 (rank : 1029)
Query Neighborhood Hits	1959	Target Neighborhood Hits	233	Shared Neighborhood Hits	198
SwissProt Accessions	O43699, O15388, O43700	Gene names	SIGLEC6, CD33L, CD33L1, OBBP1
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 6 precursor (Siglec-6) (Obesity- binding protein 1) (OB-BP1) (CD33 antigen-like 1) (CDw327 antigen).

SREC2_HUMAN
θ value	0.00390308 (rank : 966)	NC score	0.022855 (rank : 1600)
Query Neighborhood Hits	1959	Target Neighborhood Hits	645	Shared Neighborhood Hits	149
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

SRPK1_HUMAN
θ value	0.00390308 (rank : 967)	NC score	0.537527 (rank : 810)
Query Neighborhood Hits	1959	Target Neighborhood Hits	706	Shared Neighborhood Hits	593
SwissProt Accessions	Q96SB4, Q12890, Q5R364, Q5R365, Q8IY12	Gene names	SRPK1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SRPK1 (EC 2.7.11.1) (Serine/arginine- rich protein-specific kinase 1) (SR-protein-specific kinase 1) (SFRS protein kinase 1).

SRPK1_MOUSE
θ value	0.00390308 (rank : 968)	NC score	0.539174 (rank : 807)
Query Neighborhood Hits	1959	Target Neighborhood Hits	639	Shared Neighborhood Hits	573
SwissProt Accessions	O70551, O70193, Q99JT3	Gene names	Srpk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SRPK1 (EC 2.7.11.1) (Serine/arginine- rich protein-specific kinase 1) (SR-protein-specific kinase 1) (SFRS protein kinase 1).

STK23_HUMAN
θ value	0.00390308 (rank : 969)	NC score	0.535483 (rank : 814)
Query Neighborhood Hits	1959	Target Neighborhood Hits	556	Shared Neighborhood Hits	551
SwissProt Accessions	Q9UPE1, Q13583, Q9UM62	Gene names	STK23, MSSK1
Domain Architecture
Description	Serine/threonine-protein kinase 23 (EC 2.7.11.1) (Muscle-specific serine kinase 1) (MSSK-1).

STK23_MOUSE
θ value	0.00390308 (rank : 970)	NC score	0.535889 (rank : 812)
Query Neighborhood Hits	1959	Target Neighborhood Hits	572	Shared Neighborhood Hits	557
SwissProt Accessions	Q9Z0G2	Gene names	Stk23, Mssk1
Domain Architecture
Description	Serine/threonine-protein kinase 23 (EC 2.7.11.1) (Muscle-specific serine kinase 1) (MSSK-1).

TMIGD_MOUSE
θ value	0.00390308 (rank : 971)	NC score	0.310433 (rank : 937)
Query Neighborhood Hits	1959	Target Neighborhood Hits	234	Shared Neighborhood Hits	214
SwissProt Accessions	Q9D7L8, Q8R202	Gene names	Tmigd
Domain Architecture	No domain graphic available
Description	Transmembrane and immunoglobulin domain-containing protein precursor.

TNI3K_MOUSE
θ value	0.00390308 (rank : 972)	NC score	0.649571 (rank : 731)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1079	Shared Neighborhood Hits	788
SwissProt Accessions	Q5GIG6, Q5GIG5	Gene names	Tnni3k, Cark
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

MAP1A_HUMAN
θ value	0.00509761 (rank : 973)	NC score	0.060390 (rank : 1283)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1626	Shared Neighborhood Hits	398
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

PRG4_HUMAN
θ value	0.00509761 (rank : 974)	NC score	0.084057 (rank : 1158)
Query Neighborhood Hits	1959	Target Neighborhood Hits	764	Shared Neighborhood Hits	305
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRG4_MOUSE
θ value	0.00509761 (rank : 975)	NC score	0.075924 (rank : 1186)
Query Neighborhood Hits	1959	Target Neighborhood Hits	624	Shared Neighborhood Hits	242
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

RP3A_HUMAN
θ value	0.00509761 (rank : 976)	NC score	0.032749 (rank : 1493)
Query Neighborhood Hits	1959	Target Neighborhood Hits	305	Shared Neighborhood Hits	93
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

STYK1_HUMAN
θ value	0.00509761 (rank : 977)	NC score	0.656401 (rank : 721)
Query Neighborhood Hits	1959	Target Neighborhood Hits	786	Shared Neighborhood Hits	764
SwissProt Accessions	Q6J9G0, Q9BXY2, Q9NSH1	Gene names	STYK1, NOK
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (Protein PK-unique).

WIRE_HUMAN
θ value	0.00509761 (rank : 978)	NC score	0.068809 (rank : 1225)
Query Neighborhood Hits	1959	Target Neighborhood Hits	329	Shared Neighborhood Hits	178
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

CEA20_HUMAN
θ value	0.00665767 (rank : 979)	NC score	0.263268 (rank : 986)
Query Neighborhood Hits	1959	Target Neighborhood Hits	251	Shared Neighborhood Hits	197
SwissProt Accessions	Q6UY09	Gene names	CEACAM20
Domain Architecture	No domain graphic available
Description	Carcinoembryonic antigen-related cell adhesion molecule 20 precursor.

ELOA3_HUMAN
θ value	0.00665767 (rank : 980)	NC score	0.028272 (rank : 1524)
Query Neighborhood Hits	1959	Target Neighborhood Hits	98	Shared Neighborhood Hits	44
SwissProt Accessions	Q8NG57	Gene names	TCEB3C, TCEB3L2
Domain Architecture
Description	RNA polymerase II transcription factor SIII subunit A3 (Elongin-A3) (EloA3) (Transcription elongation factor B polypeptide 3C).

IL1R2_MOUSE
θ value	0.00665767 (rank : 981)	NC score	0.157845 (rank : 1044)
Query Neighborhood Hits	1959	Target Neighborhood Hits	125	Shared Neighborhood Hits	101
SwissProt Accessions	P27931	Gene names	Il1r2, Il-1r2, Il1rb
Domain Architecture
Description	Interleukin-1 receptor type II precursor (IL-1R-2) (IL-1R-beta) (CD121b antigen).

JAM3_MOUSE
θ value	0.00665767 (rank : 982)	NC score	0.289814 (rank : 953)
Query Neighborhood Hits	1959	Target Neighborhood Hits	286	Shared Neighborhood Hits	228
SwissProt Accessions	Q9D8B7, Q8BT59, Q9D1M9, Q9EPK4	Gene names	Jam3
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule C precursor (JAM-C) (Junctional adhesion molecule 3) (JAM-3) (JAM-2).

LAG3_MOUSE
θ value	0.00665767 (rank : 983)	NC score	0.109876 (rank : 1111)
Query Neighborhood Hits	1959	Target Neighborhood Hits	117	Shared Neighborhood Hits	85
SwissProt Accessions	Q61790, Q0VBL2	Gene names	Lag3
Domain Architecture
Description	Lymphocyte activation gene 3 protein precursor (LAG-3) (CD223 antigen).

MERTK_MOUSE
θ value	0.00665767 (rank : 984)	NC score	0.672949 (rank : 672)
Query Neighborhood Hits	1959	Target Neighborhood Hits	974	Shared Neighborhood Hits	906
SwissProt Accessions	Q60805, Q62194	Gene names	Mertk, Mer
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

MUC2_HUMAN
θ value	0.00665767 (rank : 985)	NC score	0.049854 (rank : 1361)
Query Neighborhood Hits	1959	Target Neighborhood Hits	906	Shared Neighborhood Hits	290
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

PRR12_HUMAN
θ value	0.00665767 (rank : 986)	NC score	0.081983 (rank : 1165)
Query Neighborhood Hits	1959	Target Neighborhood Hits	460	Shared Neighborhood Hits	217
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

SPR1A_MOUSE
θ value	0.00665767 (rank : 987)	NC score	0.056224 (rank : 1310)
Query Neighborhood Hits	1959	Target Neighborhood Hits	343	Shared Neighborhood Hits	155
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

TMIGD_HUMAN
θ value	0.00665767 (rank : 988)	NC score	0.316773 (rank : 930)
Query Neighborhood Hits	1959	Target Neighborhood Hits	240	Shared Neighborhood Hits	214
SwissProt Accessions	Q6UXZ0, Q6ZMC6	Gene names	TMIGD
Domain Architecture	No domain graphic available
Description	Transmembrane and immunoglobulin domain-containing protein precursor.

VSIG2_MOUSE
θ value	0.00665767 (rank : 989)	NC score	0.264318 (rank : 984)
Query Neighborhood Hits	1959	Target Neighborhood Hits	316	Shared Neighborhood Hits	217
SwissProt Accessions	Q9Z109, Q9CVA4, Q9D0T4	Gene names	Vsig2, Ctm, Ctxl
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 2 precursor (CT- like protein) (Cortical thymocyte-like protein).

ZEP1_MOUSE
θ value	0.00665767 (rank : 990)	NC score	-0.007920 (rank : 2057)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1063	Shared Neighborhood Hits	203
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

ARI1B_HUMAN
θ value	0.00869519 (rank : 991)	NC score	0.049140 (rank : 1370)
Query Neighborhood Hits	1959	Target Neighborhood Hits	567	Shared Neighborhood Hits	220
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

CBL_MOUSE
θ value	0.00869519 (rank : 992)	NC score	0.022106 (rank : 1608)
Query Neighborhood Hits	1959	Target Neighborhood Hits	426	Shared Neighborhood Hits	130
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

CEAM5_HUMAN
θ value	0.00869519 (rank : 993)	NC score	0.268564 (rank : 981)
Query Neighborhood Hits	1959	Target Neighborhood Hits	343	Shared Neighborhood Hits	252
SwissProt Accessions	P06731	Gene names	CEACAM5, CEA
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 5 precursor (Carcinoembryonic antigen) (CEA) (Meconium antigen 100) (CD66e antigen).

MTSS1_HUMAN
θ value	0.00869519 (rank : 994)	NC score	0.045531 (rank : 1393)
Query Neighborhood Hits	1959	Target Neighborhood Hits	504	Shared Neighborhood Hits	175
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

NRG2_HUMAN
θ value	0.00869519 (rank : 995)	NC score	0.256482 (rank : 988)
Query Neighborhood Hits	1959	Target Neighborhood Hits	419	Shared Neighborhood Hits	258
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

PCLO_MOUSE
θ value	0.00869519 (rank : 996)	NC score	0.092988 (rank : 1140)
Query Neighborhood Hits	1959	Target Neighborhood Hits	2275	Shared Neighborhood Hits	654
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

UBP42_HUMAN
θ value	0.00869519 (rank : 997)	NC score	0.018802 (rank : 1658)
Query Neighborhood Hits	1959	Target Neighborhood Hits	445	Shared Neighborhood Hits	153
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

YLPM1_MOUSE
θ value	0.00869519 (rank : 998)	NC score	0.058529 (rank : 1293)
Query Neighborhood Hits	1959	Target Neighborhood Hits	505	Shared Neighborhood Hits	218
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

ALEX_HUMAN
θ value	0.0113563 (rank : 999)	NC score	0.073715 (rank : 1198)
Query Neighborhood Hits	1959	Target Neighborhood Hits	361	Shared Neighborhood Hits	195
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

CN092_MOUSE
θ value	0.0113563 (rank : 1000)	NC score	0.024429 (rank : 1570)
Query Neighborhood Hits	1959	Target Neighborhood Hits	206	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BU11, Q80UI2, Q99PN9, Q9CS16	Gene names
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

CSKI2_MOUSE
θ value	0.0113563 (rank : 1001)	NC score	0.041235 (rank : 1430)
Query Neighborhood Hits	1959	Target Neighborhood Hits	812	Shared Neighborhood Hits	249
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

IWS1_MOUSE
θ value	0.0113563 (rank : 1002)	NC score	0.050522 (rank : 1351)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1258	Shared Neighborhood Hits	333
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

NEB2_HUMAN
θ value	0.0113563 (rank : 1003)	NC score	0.023176 (rank : 1593)
Query Neighborhood Hits	1959	Target Neighborhood Hits	883	Shared Neighborhood Hits	139
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

RP3A_MOUSE
θ value	0.0113563 (rank : 1004)	NC score	0.036898 (rank : 1464)
Query Neighborhood Hits	1959	Target Neighborhood Hits	510	Shared Neighborhood Hits	203
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SVIL_MOUSE
θ value	0.0113563 (rank : 1005)	NC score	0.036669 (rank : 1465)
Query Neighborhood Hits	1959	Target Neighborhood Hits	439	Shared Neighborhood Hits	131
SwissProt Accessions	Q8K4L3	Gene names	Svil
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

SYN1_MOUSE
θ value	0.0113563 (rank : 1006)	NC score	0.053696 (rank : 1325)
Query Neighborhood Hits	1959	Target Neighborhood Hits	363	Shared Neighborhood Hits	187
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

CS016_HUMAN
θ value	0.0148317 (rank : 1007)	NC score	0.066529 (rank : 1242)
Query Neighborhood Hits	1959	Target Neighborhood Hits	310	Shared Neighborhood Hits	160
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

EFS_HUMAN
θ value	0.0148317 (rank : 1008)	NC score	0.047075 (rank : 1382)
Query Neighborhood Hits	1959	Target Neighborhood Hits	348	Shared Neighborhood Hits	146
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

EPHB6_HUMAN
θ value	0.0148317 (rank : 1009)	NC score	0.553618 (rank : 803)
Query Neighborhood Hits	1959	Target Neighborhood Hits	912	Shared Neighborhood Hits	754
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

MFA3L_HUMAN
θ value	0.0148317 (rank : 1010)	NC score	0.269228 (rank : 980)
Query Neighborhood Hits	1959	Target Neighborhood Hits	230	Shared Neighborhood Hits	209
SwissProt Accessions	O75121, Q6TNA8, Q9BVE1, Q9BXK0	Gene names	MFAP3L, KIAA0626
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 3-like precursor (Protein kinase NYD-SP9).

NCOR2_HUMAN
θ value	0.0148317 (rank : 1011)	NC score	0.061082 (rank : 1278)
Query Neighborhood Hits	1959	Target Neighborhood Hits	870	Shared Neighborhood Hits	287
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

PDZD2_HUMAN
θ value	0.0148317 (rank : 1012)	NC score	0.040011 (rank : 1441)
Query Neighborhood Hits	1959	Target Neighborhood Hits	772	Shared Neighborhood Hits	250
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

SYNPO_HUMAN
θ value	0.0148317 (rank : 1013)	NC score	0.043619 (rank : 1410)
Query Neighborhood Hits	1959	Target Neighborhood Hits	281	Shared Neighborhood Hits	144
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

WASL_HUMAN
θ value	0.0148317 (rank : 1014)	NC score	0.067680 (rank : 1233)
Query Neighborhood Hits	1959	Target Neighborhood Hits	312	Shared Neighborhood Hits	170
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

BSN_HUMAN
θ value	0.0193708 (rank : 1015)	NC score	0.086890 (rank : 1152)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1537	Shared Neighborhood Hits	486
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CILP1_HUMAN
θ value	0.0193708 (rank : 1016)	NC score	0.151858 (rank : 1055)
Query Neighborhood Hits	1959	Target Neighborhood Hits	266	Shared Neighborhood Hits	171
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

GUC2D_HUMAN
θ value	0.0193708 (rank : 1017)	NC score	0.464056 (rank : 825)
Query Neighborhood Hits	1959	Target Neighborhood Hits	715	Shared Neighborhood Hits	655
SwissProt Accessions	Q02846, Q6LEA7	Gene names	GUCY2D, CORD6, GUC1A4, GUC2D, RETGC, RETGC1
Domain Architecture
Description	Retinal guanylyl cyclase 1 precursor (EC 4.6.1.2) (Guanylate cyclase 2D, retinal) (RETGC-1) (Rod outer segment membrane guanylate cyclase) (ROS-GC).

MOR2A_MOUSE
θ value	0.0193708 (rank : 1018)	NC score	0.020439 (rank : 1638)
Query Neighborhood Hits	1959	Target Neighborhood Hits	220	Shared Neighborhood Hits	70
SwissProt Accessions	Q69ZX6, Q5QNQ7, Q6P547	Gene names	Morc2a, Kiaa0852, Zcwcc1
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 2A (Zinc finger CW-type coiled-coil domain protein 1).

NEB2_MOUSE
θ value	0.0193708 (rank : 1019)	NC score	0.025213 (rank : 1563)
Query Neighborhood Hits	1959	Target Neighborhood Hits	889	Shared Neighborhood Hits	142
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NRG2_MOUSE
θ value	0.0193708 (rank : 1020)	NC score	0.248330 (rank : 993)
Query Neighborhood Hits	1959	Target Neighborhood Hits	392	Shared Neighborhood Hits	239
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

PI5PA_HUMAN
θ value	0.0193708 (rank : 1021)	NC score	0.064006 (rank : 1259)
Query Neighborhood Hits	1959	Target Neighborhood Hits	749	Shared Neighborhood Hits	349
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

RP1L1_HUMAN
θ value	0.0193708 (rank : 1022)	NC score	0.059684 (rank : 1288)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1072	Shared Neighborhood Hits	285
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

USH2A_HUMAN
θ value	0.0193708 (rank : 1023)	NC score	0.130331 (rank : 1075)
Query Neighborhood Hits	1959	Target Neighborhood Hits	600	Shared Neighborhood Hits	161
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

VRK2_MOUSE
θ value	0.0193708 (rank : 1024)	NC score	0.482602 (rank : 819)
Query Neighborhood Hits	1959	Target Neighborhood Hits	586	Shared Neighborhood Hits	575
SwissProt Accessions	Q8BN21, Q5F1Z5, Q5SP88, Q8BPU8, Q8CJ46, Q91WS1, Q9CZF9	Gene names	Vrk2
Domain Architecture
Description	Serine/threonine-protein kinase VRK2 (EC 2.7.11.1) (Vaccinia-related kinase 2).

WIRE_MOUSE
θ value	0.0193708 (rank : 1025)	NC score	0.063312 (rank : 1264)
Query Neighborhood Hits	1959	Target Neighborhood Hits	310	Shared Neighborhood Hits	168
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

CENG1_HUMAN
θ value	0.0252991 (rank : 1026)	NC score	0.004081 (rank : 1893)
Query Neighborhood Hits	1959	Target Neighborhood Hits	544	Shared Neighborhood Hits	103
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

ESPL1_MOUSE
θ value	0.0252991 (rank : 1027)	NC score	0.019052 (rank : 1653)
Query Neighborhood Hits	1959	Target Neighborhood Hits	67	Shared Neighborhood Hits	13
SwissProt Accessions	P60330	Gene names	Espl1, Esp1, Kiaa0165
Domain Architecture
Description	Separin (EC 3.4.22.49) (Separase) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein).

GSCR1_HUMAN
θ value	0.0252991 (rank : 1028)	NC score	0.076267 (rank : 1185)
Query Neighborhood Hits	1959	Target Neighborhood Hits	674	Shared Neighborhood Hits	295
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

IBP7_MOUSE
θ value	0.0252991 (rank : 1029)	NC score	0.236118 (rank : 997)
Query Neighborhood Hits	1959	Target Neighborhood Hits	230	Shared Neighborhood Hits	161
SwissProt Accessions	Q61581, O88812, Q9EQW0	Gene names	Igfbp7, Mac25
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).

NPTN_HUMAN
θ value	0.0252991 (rank : 1030)	NC score	0.299495 (rank : 945)
Query Neighborhood Hits	1959	Target Neighborhood Hits	212	Shared Neighborhood Hits	197
SwissProt Accessions	Q9Y639, Q59EJ9, Q6NVX7, Q9Y640	Gene names	NPTN, SDFR1, SDR1
Domain Architecture	No domain graphic available
Description	Neuroplastin precursor (Stromal cell-derived receptor 1) (SDR-1).

SYN3_HUMAN
θ value	0.0252991 (rank : 1031)	NC score	0.035417 (rank : 1470)
Query Neighborhood Hits	1959	Target Neighborhood Hits	203	Shared Neighborhood Hits	98
SwissProt Accessions	O14994	Gene names	SYN3
Domain Architecture
Description	Synapsin-3 (Synapsin III).

TARSH_HUMAN
θ value	0.0252991 (rank : 1032)	NC score	0.155206 (rank : 1048)
Query Neighborhood Hits	1959	Target Neighborhood Hits	768	Shared Neighborhood Hits	393
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

TGFR1_HUMAN
θ value	0.0252991 (rank : 1033)	NC score	0.599481 (rank : 782)
Query Neighborhood Hits	1959	Target Neighborhood Hits	755	Shared Neighborhood Hits	735
SwissProt Accessions	P36897	Gene names	TGFBR1
Domain Architecture
Description	TGF-beta receptor type-1 precursor (EC 2.7.11.30) (TGF-beta receptor type I) (TGFR-1) (TGF-beta type I receptor) (Serine/threonine-protein kinase receptor R4) (SKR4) (Activin receptor-like kinase 5) (ALK-5).

TGFR1_MOUSE
θ value	0.0252991 (rank : 1034)	NC score	0.599139 (rank : 783)
Query Neighborhood Hits	1959	Target Neighborhood Hits	753	Shared Neighborhood Hits	735
SwissProt Accessions	Q64729	Gene names	Tgfbr1
Domain Architecture
Description	TGF-beta receptor type-1 precursor (EC 2.7.11.30) (TGF-beta receptor type I) (TGFR-1) (TGF-beta type I receptor) (ESK2).

ACINU_MOUSE
θ value	0.0330416 (rank : 1035)	NC score	0.046238 (rank : 1386)
Query Neighborhood Hits	1959	Target Neighborhood Hits	712	Shared Neighborhood Hits	187
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

KAZD1_HUMAN
θ value	0.0330416 (rank : 1036)	NC score	0.256338 (rank : 989)
Query Neighborhood Hits	1959	Target Neighborhood Hits	248	Shared Neighborhood Hits	165
SwissProt Accessions	Q96I82, Q6ZMB1, Q9BQ73	Gene names	KAZALD1
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor.

LRRC4_HUMAN
θ value	0.0330416 (rank : 1037)	NC score	0.109237 (rank : 1113)
Query Neighborhood Hits	1959	Target Neighborhood Hits	444	Shared Neighborhood Hits	201
SwissProt Accessions	Q9HBW1, Q6ZMI8, Q96A85	Gene names	LRRC4, BAG
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4 precursor (Brain tumor- associated protein LRRC4) (NAG14).

MLL3_HUMAN
θ value	0.0330416 (rank : 1038)	NC score	0.057303 (rank : 1302)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1644	Shared Neighborhood Hits	476
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MYO15_HUMAN
θ value	0.0330416 (rank : 1039)	NC score	0.028776 (rank : 1520)
Query Neighborhood Hits	1959	Target Neighborhood Hits	671	Shared Neighborhood Hits	286
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

NCOA6_MOUSE
θ value	0.0330416 (rank : 1040)	NC score	0.078683 (rank : 1177)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1076	Shared Neighborhood Hits	388
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

NFH_HUMAN
θ value	0.0330416 (rank : 1041)	NC score	0.026046 (rank : 1544)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1242	Shared Neighborhood Hits	269
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

NPTN_MOUSE
θ value	0.0330416 (rank : 1042)	NC score	0.298410 (rank : 946)
Query Neighborhood Hits	1959	Target Neighborhood Hits	216	Shared Neighborhood Hits	197
SwissProt Accessions	P97300, Q3U519, Q8C637, Q8C6H8	Gene names	Nptn, Sdfr1, Sdr1
Domain Architecture	No domain graphic available
Description	Neuroplastin precursor (Stromal cell-derived receptor 1) (SDR-1).

PCLO_HUMAN
θ value	0.0330416 (rank : 1043)	NC score	0.088549 (rank : 1145)
Query Neighborhood Hits	1959	Target Neighborhood Hits	2046	Shared Neighborhood Hits	576
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PSL1_HUMAN
θ value	0.0330416 (rank : 1044)	NC score	0.052533 (rank : 1331)
Query Neighborhood Hits	1959	Target Neighborhood Hits	650	Shared Neighborhood Hits	280
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

RTP3_MOUSE
θ value	0.0330416 (rank : 1045)	NC score	0.053447 (rank : 1326)
Query Neighborhood Hits	1959	Target Neighborhood Hits	374	Shared Neighborhood Hits	171
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

SEPT9_HUMAN
θ value	0.0330416 (rank : 1046)	NC score	0.042086 (rank : 1423)
Query Neighborhood Hits	1959	Target Neighborhood Hits	706	Shared Neighborhood Hits	299
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

SIGL7_HUMAN
θ value	0.0330416 (rank : 1047)	NC score	0.139548 (rank : 1068)
Query Neighborhood Hits	1959	Target Neighborhood Hits	180	Shared Neighborhood Hits	156
SwissProt Accessions	Q9Y286, Q9NZQ1, Q9UJ86, Q9UJ87, Q9Y502	Gene names	SIGLEC7, AIRM1
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 7 precursor (Siglec-7) (QA79 membrane protein) (Adhesion inhibitory receptor molecule 1) (AIRM-1) (p75) (D-siglec) (CDw328 antigen).

SVIL_HUMAN
θ value	0.0330416 (rank : 1048)	NC score	0.030142 (rank : 1510)
Query Neighborhood Hits	1959	Target Neighborhood Hits	232	Shared Neighborhood Hits	78
SwissProt Accessions	O95425, O60611, O60612, Q5VZK5, Q5VZK6, Q9H1R7	Gene names	SVIL
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

TARA_HUMAN
θ value	0.0330416 (rank : 1049)	NC score	0.079219 (rank : 1176)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1626	Shared Neighborhood Hits	463
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TGFR2_HUMAN
θ value	0.0330416 (rank : 1050)	NC score	0.631277 (rank : 754)
Query Neighborhood Hits	1959	Target Neighborhood Hits	748	Shared Neighborhood Hits	728
SwissProt Accessions	P37173, Q15580, Q6DKT6, Q99474	Gene names	TGFBR2
Domain Architecture
Description	TGF-beta receptor type-2 precursor (EC 2.7.11.30) (TGF-beta receptor type II) (TGFR-2) (TGF-beta type II receptor).

TGFR2_MOUSE
θ value	0.0330416 (rank : 1051)	NC score	0.631444 (rank : 753)
Query Neighborhood Hits	1959	Target Neighborhood Hits	748	Shared Neighborhood Hits	729
SwissProt Accessions	Q62312, Q63947	Gene names	Tgfbr2
Domain Architecture
Description	TGF-beta receptor type-2 precursor (EC 2.7.11.30) (TGF-beta receptor type II) (TGFR-2) (TGF-beta type II receptor).

WASL_MOUSE
θ value	0.0330416 (rank : 1052)	NC score	0.062821 (rank : 1266)
Query Neighborhood Hits	1959	Target Neighborhood Hits	339	Shared Neighborhood Hits	172
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

BAT2_MOUSE
θ value	0.0431538 (rank : 1053)	NC score	0.067621 (rank : 1234)
Query Neighborhood Hits	1959	Target Neighborhood Hits	947	Shared Neighborhood Hits	384
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BMR1A_HUMAN
θ value	0.0431538 (rank : 1054)	NC score	0.609294 (rank : 774)
Query Neighborhood Hits	1959	Target Neighborhood Hits	759	Shared Neighborhood Hits	736
SwissProt Accessions	P36894, Q8NEN8	Gene names	BMPR1A, ACVRLK3, ALK3
Domain Architecture
Description	Bone morphogenetic protein receptor type IA precursor (EC 2.7.11.30) (Serine/threonine-protein kinase receptor R5) (SKR5) (Activin receptor-like kinase 3) (ALK-3) (CD292 antigen).

BMR1A_MOUSE
θ value	0.0431538 (rank : 1055)	NC score	0.608372 (rank : 776)
Query Neighborhood Hits	1959	Target Neighborhood Hits	758	Shared Neighborhood Hits	736
SwissProt Accessions	P36895	Gene names	Bmpr1a, Acvrlk3, Bmpr
Domain Architecture
Description	Bone morphogenetic protein receptor type IA precursor (EC 2.7.11.30) (Serine/threonine-protein kinase receptor R5) (SKR5) (Activin receptor-like kinase 3) (ALK-3) (BMP-2/BMP-4 receptor).

DIDO1_HUMAN
θ value	0.0431538 (rank : 1056)	NC score	0.046270 (rank : 1385)
Query Neighborhood Hits	1959	Target Neighborhood Hits	960	Shared Neighborhood Hits	310
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

DREB_HUMAN
θ value	0.0431538 (rank : 1057)	NC score	0.042640 (rank : 1418)
Query Neighborhood Hits	1959	Target Neighborhood Hits	450	Shared Neighborhood Hits	106
SwissProt Accessions	Q16643	Gene names	DBN1
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

GPA33_MOUSE
θ value	0.0431538 (rank : 1058)	NC score	0.221924 (rank : 1004)
Query Neighborhood Hits	1959	Target Neighborhood Hits	294	Shared Neighborhood Hits	183
SwissProt Accessions	Q9JKA5, Q922D5	Gene names	Gpa33
Domain Architecture
Description	Cell surface A33 antigen precursor (Glycoprotein A33) (mA33).

MBB1A_HUMAN
θ value	0.0431538 (rank : 1059)	NC score	0.063446 (rank : 1262)
Query Neighborhood Hits	1959	Target Neighborhood Hits	665	Shared Neighborhood Hits	269
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

MUC7_HUMAN
θ value	0.0431538 (rank : 1060)	NC score	0.082202 (rank : 1164)
Query Neighborhood Hits	1959	Target Neighborhood Hits	538	Shared Neighborhood Hits	246
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

NRG1_HUMAN
θ value	0.0431538 (rank : 1061)	NC score	0.193000 (rank : 1011)
Query Neighborhood Hits	1959	Target Neighborhood Hits	285	Shared Neighborhood Hits	170
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

PAX1_HUMAN
θ value	0.0431538 (rank : 1062)	NC score	0.007838 (rank : 1827)
Query Neighborhood Hits	1959	Target Neighborhood Hits	72	Shared Neighborhood Hits	24
SwissProt Accessions	P15863, Q642X9, Q6NTC0, Q9Y558	Gene names	PAX1, HUP48
Domain Architecture
Description	Paired box protein Pax-1 (HUP48).

PSG3_HUMAN
θ value	0.0431538 (rank : 1063)	NC score	0.175530 (rank : 1028)
Query Neighborhood Hits	1959	Target Neighborhood Hits	242	Shared Neighborhood Hits	196
SwissProt Accessions	Q16557, Q08265, Q9BRW2, Q9UPL4, Q9UQ77	Gene names	PSG3
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 3 precursor (PSBG-3) (Carcinoembryonic antigen SG5).

UNC5D_HUMAN
θ value	0.0431538 (rank : 1064)	NC score	0.152936 (rank : 1052)
Query Neighborhood Hits	1959	Target Neighborhood Hits	267	Shared Neighborhood Hits	179
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

UNC5D_MOUSE
θ value	0.0431538 (rank : 1065)	NC score	0.154748 (rank : 1049)
Query Neighborhood Hits	1959	Target Neighborhood Hits	268	Shared Neighborhood Hits	179
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

ACVR1_MOUSE
θ value	0.0563607 (rank : 1066)	NC score	0.622615 (rank : 764)
Query Neighborhood Hits	1959	Target Neighborhood Hits	768	Shared Neighborhood Hits	748
SwissProt Accessions	P37172, Q3UDH5, Q91VF1	Gene names	Acvr1, Acvrlk2, Tgfb1
Domain Architecture
Description	Activin receptor type-1 precursor (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) (Serine/threonine-protein kinase receptor R1) (SKR1) (TGF-B superfamily receptor type I) (TSR-I) (TSK-7L).

BASP_HUMAN
θ value	0.0563607 (rank : 1067)	NC score	0.072615 (rank : 1204)
Query Neighborhood Hits	1959	Target Neighborhood Hits	321	Shared Neighborhood Hits	133
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BUB1_HUMAN
θ value	0.0563607 (rank : 1068)	NC score	0.405156 (rank : 844)
Query Neighborhood Hits	1959	Target Neighborhood Hits	543	Shared Neighborhood Hits	426
SwissProt Accessions	O43683, O43430, O43643, O60626	Gene names	BUB1, BUB1L
Domain Architecture
Description	Mitotic checkpoint serine/threonine-protein kinase BUB1 (EC 2.7.11.1) (hBUB1) (BUB1A).

CDC7_HUMAN
θ value	0.0563607 (rank : 1069)	NC score	0.679128 (rank : 659)
Query Neighborhood Hits	1959	Target Neighborhood Hits	652	Shared Neighborhood Hits	630
SwissProt Accessions	O00311, O00558	Gene names	CDC7, CDC7L1
Domain Architecture
Description	Cell division cycle 7-related protein kinase (EC 2.7.11.1) (CDC7- related kinase) (HsCdc7) (huCdc7).

FOG1_HUMAN
θ value	0.0563607 (rank : 1070)	NC score	-0.006491 (rank : 2051)
Query Neighborhood Hits	1959	Target Neighborhood Hits	981	Shared Neighborhood Hits	188
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

FOXD2_MOUSE
θ value	0.0563607 (rank : 1071)	NC score	0.001290 (rank : 1949)
Query Neighborhood Hits	1959	Target Neighborhood Hits	130	Shared Neighborhood Hits	34
SwissProt Accessions	O35392	Gene names	Foxd2, Mf2
Domain Architecture
Description	Forkhead box protein D2 (Mesoderm/mesenchyme forkhead 2) (MF-2).

GUC2G_MOUSE
θ value	0.0563607 (rank : 1072)	NC score	0.443614 (rank : 827)
Query Neighborhood Hits	1959	Target Neighborhood Hits	644	Shared Neighborhood Hits	572
SwissProt Accessions	Q6TL19, Q8BWU7	Gene names	Gucy2g
Domain Architecture	No domain graphic available
Description	Guanylate cyclase 2G precursor (EC 4.6.1.2) (Guanylyl cyclase receptor G) (mGC-G).

IASPP_MOUSE
θ value	0.0563607 (rank : 1073)	NC score	0.062935 (rank : 1265)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1024	Shared Neighborhood Hits	344
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

NFRKB_MOUSE
θ value	0.0563607 (rank : 1074)	NC score	0.041606 (rank : 1427)
Query Neighborhood Hits	1959	Target Neighborhood Hits	393	Shared Neighborhood Hits	176
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

PHLB1_HUMAN
θ value	0.0563607 (rank : 1075)	NC score	0.046073 (rank : 1389)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1038	Shared Neighborhood Hits	269
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PHLB1_MOUSE
θ value	0.0563607 (rank : 1076)	NC score	0.035361 (rank : 1471)
Query Neighborhood Hits	1959	Target Neighborhood Hits	678	Shared Neighborhood Hits	174
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PO6F1_MOUSE
θ value	0.0563607 (rank : 1077)	NC score	0.012716 (rank : 1748)
Query Neighborhood Hits	1959	Target Neighborhood Hits	581	Shared Neighborhood Hits	159
SwissProt Accessions	Q07916, Q91XK3	Gene names	Pou6f1, Emb
Domain Architecture
Description	POU domain, class 6, transcription factor 1 (Octamer-binding transcription factor EMB) (Transcription regulatory protein MCP-1).

SEPT9_MOUSE
θ value	0.0563607 (rank : 1078)	NC score	0.019679 (rank : 1645)
Query Neighborhood Hits	1959	Target Neighborhood Hits	238	Shared Neighborhood Hits	91
SwissProt Accessions	Q80UG5, Q3URP2, Q80TM7, Q9QYX9	Gene names	Sept9, Kiaa0991, Sint1
Domain Architecture	No domain graphic available
Description	Septin-9 (SL3-3 integration site 1 protein).

SET1A_HUMAN
θ value	0.0563607 (rank : 1079)	NC score	0.060907 (rank : 1280)
Query Neighborhood Hits	1959	Target Neighborhood Hits	690	Shared Neighborhood Hits	245
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SIGL5_MOUSE
θ value	0.0563607 (rank : 1080)	NC score	0.221023 (rank : 1005)
Query Neighborhood Hits	1959	Target Neighborhood Hits	271	Shared Neighborhood Hits	223
SwissProt Accessions	Q920G3	Gene names	Siglec5, Siglecf
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 5 precursor (Siglec-5) (Sialic acid-binding Ig-like lectin-F) (mSiglec-F).

TROAP_HUMAN
θ value	0.0563607 (rank : 1081)	NC score	0.046300 (rank : 1384)
Query Neighborhood Hits	1959	Target Neighborhood Hits	258	Shared Neighborhood Hits	134
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

UBP21_MOUSE
θ value	0.0563607 (rank : 1082)	NC score	0.000091 (rank : 1970)
Query Neighborhood Hits	1959	Target Neighborhood Hits	101	Shared Neighborhood Hits	16
SwissProt Accessions	Q9QZL6, Q9D0R1	Gene names	Usp21, Usp23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21).

UNC5A_HUMAN
θ value	0.0563607 (rank : 1083)	NC score	0.123091 (rank : 1092)
Query Neighborhood Hits	1959	Target Neighborhood Hits	198	Shared Neighborhood Hits	131
SwissProt Accessions	Q6ZN44, Q8TF26, Q96GP4	Gene names	UNC5A, KIAA1976, UNC5H1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

WASIP_HUMAN
θ value	0.0563607 (rank : 1084)	NC score	0.081967 (rank : 1166)
Query Neighborhood Hits	1959	Target Neighborhood Hits	458	Shared Neighborhood Hits	219
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

WWP1_HUMAN
θ value	0.0563607 (rank : 1085)	NC score	0.002239 (rank : 1930)
Query Neighborhood Hits	1959	Target Neighborhood Hits	262	Shared Neighborhood Hits	80
SwissProt Accessions	Q9H0M0, O00307, Q96BP4	Gene names	WWP1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1) (Atropin-1-interacting protein 5) (AIP5).

ACVR1_HUMAN
θ value	0.0736092 (rank : 1086)	NC score	0.616553 (rank : 770)
Query Neighborhood Hits	1959	Target Neighborhood Hits	760	Shared Neighborhood Hits	742
SwissProt Accessions	Q04771	Gene names	ACVR1, ACVRLK2
Domain Architecture
Description	Activin receptor type-1 precursor (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) (Serine/threonine-protein kinase receptor R1) (SKR1) (Activin receptor-like kinase 2) (ALK-2) (TGF-B superfamily receptor type I) (TSR-I).

BAT2_HUMAN
θ value	0.0736092 (rank : 1087)	NC score	0.079842 (rank : 1174)
Query Neighborhood Hits	1959	Target Neighborhood Hits	931	Shared Neighborhood Hits	384
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CAC1B_HUMAN
θ value	0.0736092 (rank : 1088)	NC score	0.003900 (rank : 1898)
Query Neighborhood Hits	1959	Target Neighborhood Hits	257	Shared Neighborhood Hits	73
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

DVL3_HUMAN
θ value	0.0736092 (rank : 1089)	NC score	0.006914 (rank : 1843)
Query Neighborhood Hits	1959	Target Neighborhood Hits	194	Shared Neighborhood Hits	38
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

LARP4_HUMAN
θ value	0.0736092 (rank : 1090)	NC score	0.023527 (rank : 1584)
Query Neighborhood Hits	1959	Target Neighborhood Hits	69	Shared Neighborhood Hits	28
SwissProt Accessions	Q71RC2, Q5CZ97, Q96NF9	Gene names	LARP4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

MAP1B_MOUSE
θ value	0.0736092 (rank : 1091)	NC score	0.048274 (rank : 1378)
Query Neighborhood Hits	1959	Target Neighborhood Hits	977	Shared Neighborhood Hits	226
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

MORC2_HUMAN
θ value	0.0736092 (rank : 1092)	NC score	0.024459 (rank : 1568)
Query Neighborhood Hits	1959	Target Neighborhood Hits	207	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y6X9, Q9UF28, Q9Y6V2	Gene names	MORC2, KIAA0852, ZCWCC1
Domain Architecture
Description	MORC family CW-type zinc finger protein 2 (Zinc finger CW-type coiled- coil domain protein 1).

PECA1_MOUSE
θ value	0.0736092 (rank : 1093)	NC score	0.123999 (rank : 1089)
Query Neighborhood Hits	1959	Target Neighborhood Hits	126	Shared Neighborhood Hits	100
SwissProt Accessions	Q08481	Gene names	Pecam1, Pecam, Pecam-1
Domain Architecture
Description	Platelet endothelial cell adhesion molecule precursor (PECAM-1) (CD31 antigen).

PRP1_HUMAN
θ value	0.0736092 (rank : 1094)	NC score	0.080909 (rank : 1169)
Query Neighborhood Hits	1959	Target Neighborhood Hits	385	Shared Neighborhood Hits	179
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

SPR1A_HUMAN
θ value	0.0736092 (rank : 1095)	NC score	0.044600 (rank : 1401)
Query Neighborhood Hits	1959	Target Neighborhood Hits	136	Shared Neighborhood Hits	58
SwissProt Accessions	P35321, Q9UDG4	Gene names	SPRR1A
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein IA) (SPR-IA) (SPRK) (19 kDa pancornulin).

SPRR3_HUMAN
θ value	0.0736092 (rank : 1096)	NC score	0.054455 (rank : 1321)
Query Neighborhood Hits	1959	Target Neighborhood Hits	102	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UBC9, O75597, Q4ZGI7, Q5T525, Q8NET7, Q9UDG3	Gene names	SPRR3, SPRC
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta) (Esophagin) (22 kDa pancornulin).

SYN1_HUMAN
θ value	0.0736092 (rank : 1097)	NC score	0.055901 (rank : 1313)
Query Neighborhood Hits	1959	Target Neighborhood Hits	419	Shared Neighborhood Hits	207
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

TMPSD_MOUSE
θ value	0.0736092 (rank : 1098)	NC score	-0.005179 (rank : 2040)
Query Neighborhood Hits	1959	Target Neighborhood Hits	334	Shared Neighborhood Hits	82
SwissProt Accessions	Q5U405, Q8CFE0, Q91VQ8	Gene names	Tmprss13, Msp
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

ANK2_HUMAN
θ value	0.0961366 (rank : 1099)	NC score	0.046165 (rank : 1388)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1615	Shared Neighborhood Hits	451
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ANPRA_HUMAN
θ value	0.0961366 (rank : 1100)	NC score	0.412253 (rank : 834)
Query Neighborhood Hits	1959	Target Neighborhood Hits	612	Shared Neighborhood Hits	535
SwissProt Accessions	P16066, Q6P4Q3	Gene names	NPR1, ANPRA
Domain Architecture
Description	Atrial natriuretic peptide receptor A precursor (ANP-A) (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor).

BAG4_HUMAN
θ value	0.0961366 (rank : 1101)	NC score	0.024309 (rank : 1571)
Query Neighborhood Hits	1959	Target Neighborhood Hits	96	Shared Neighborhood Hits	38
SwissProt Accessions	O95429, O95818	Gene names	BAG4, SODD
Domain Architecture
Description	BAG family molecular chaperone regulator 4 (BCL2-associated athanogene 4) (BAG-4) (Silencer of death domains).

BASI_HUMAN
θ value	0.0961366 (rank : 1102)	NC score	0.264588 (rank : 983)
Query Neighborhood Hits	1959	Target Neighborhood Hits	211	Shared Neighborhood Hits	188
SwissProt Accessions	P35613, Q7Z796, Q8IZL7	Gene names	BSG
Domain Architecture
Description	Basigin precursor (Leukocyte activation antigen M6) (Collagenase stimulatory factor) (Extracellular matrix metalloproteinase inducer) (EMMPRIN) (5F7) (Tumor cell-derived collagenase stimulatory factor) (TCSF) (OK blood group antigen) (CD147 antigen).

BMPR2_MOUSE
θ value	0.0961366 (rank : 1103)	NC score	0.584528 (rank : 793)
Query Neighborhood Hits	1959	Target Neighborhood Hits	738	Shared Neighborhood Hits	697
SwissProt Accessions	O35607	Gene names	Bmpr2
Domain Architecture
Description	Bone morphogenetic protein receptor type-2 precursor (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II) (BRK-3).

CILP1_MOUSE
θ value	0.0961366 (rank : 1104)	NC score	0.160301 (rank : 1042)
Query Neighborhood Hits	1959	Target Neighborhood Hits	282	Shared Neighborhood Hits	191
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

GUC2E_MOUSE
θ value	0.0961366 (rank : 1105)	NC score	0.442430 (rank : 829)
Query Neighborhood Hits	1959	Target Neighborhood Hits	692	Shared Neighborhood Hits	627
SwissProt Accessions	P52785	Gene names	Gucy2e, Guc2e
Domain Architecture
Description	Guanylyl cyclase GC-E precursor (EC 4.6.1.2) (Guanylate cyclase 2E).

HHLA2_HUMAN
θ value	0.0961366 (rank : 1106)	NC score	0.099622 (rank : 1131)
Query Neighborhood Hits	1959	Target Neighborhood Hits	140	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UM44, Q9NWQ6	Gene names	HHLA2
Domain Architecture	No domain graphic available
Description	HERV-H LTR-associating protein 2 precursor (Human endogenous retrovirus-H long terminal repeat-associating protein 2).

JADE2_HUMAN
θ value	0.0961366 (rank : 1107)	NC score	0.010783 (rank : 1780)
Query Neighborhood Hits	1959	Target Neighborhood Hits	199	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

KLF17_HUMAN
θ value	0.0961366 (rank : 1108)	NC score	-0.018741 (rank : 2092)
Query Neighborhood Hits	1959	Target Neighborhood Hits	882	Shared Neighborhood Hits	148
SwissProt Accessions	Q5JT82, Q86VQ7, Q8N805	Gene names	KLF17, ZNF393
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 17 (Zinc finger protein 393).

LARP4_MOUSE
θ value	0.0961366 (rank : 1109)	NC score	0.033822 (rank : 1483)
Query Neighborhood Hits	1959	Target Neighborhood Hits	260	Shared Neighborhood Hits	122
SwissProt Accessions	Q8BWW4, Q3UR69	Gene names	Larp4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

PHC1_HUMAN
θ value	0.0961366 (rank : 1110)	NC score	0.027865 (rank : 1529)
Query Neighborhood Hits	1959	Target Neighborhood Hits	227	Shared Neighborhood Hits	91
SwissProt Accessions	P78364, Q8WVM3, Q9BU63	Gene names	PHC1, EDR1, PH1
Domain Architecture
Description	Polyhomeotic-like protein 1 (hPH1) (Early development regulatory protein 1).

UBQL3_HUMAN
θ value	0.0961366 (rank : 1111)	NC score	0.014000 (rank : 1730)
Query Neighborhood Hits	1959	Target Neighborhood Hits	141	Shared Neighborhood Hits	53
SwissProt Accessions	Q9H347, Q9NRE0	Gene names	UBQLN3
Domain Architecture
Description	Ubiquilin-3.

AIM1_HUMAN
θ value	0.125558 (rank : 1112)	NC score	0.025935 (rank : 1547)
Query Neighborhood Hits	1959	Target Neighborhood Hits	247	Shared Neighborhood Hits	100
SwissProt Accessions	Q9Y4K1, O00296, Q5VWJ2	Gene names	AIM1
Domain Architecture
Description	Absent in melanoma 1 protein.

AKAP2_HUMAN
θ value	0.125558 (rank : 1113)	NC score	0.022405 (rank : 1606)
Query Neighborhood Hits	1959	Target Neighborhood Hits	507	Shared Neighborhood Hits	111
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

AL2S4_MOUSE
θ value	0.125558 (rank : 1114)	NC score	0.039807 (rank : 1443)
Query Neighborhood Hits	1959	Target Neighborhood Hits	193	Shared Neighborhood Hits	90
SwissProt Accessions	Q3V0J1, Q3TIS2	Gene names	Als2cr4
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein homolog.

ALO17_HUMAN
θ value	0.125558 (rank : 1115)	NC score	0.028409 (rank : 1523)
Query Neighborhood Hits	1959	Target Neighborhood Hits	317	Shared Neighborhood Hits	79
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

BCAR1_HUMAN
θ value	0.125558 (rank : 1116)	NC score	0.043961 (rank : 1407)
Query Neighborhood Hits	1959	Target Neighborhood Hits	554	Shared Neighborhood Hits	222
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

CCDC6_HUMAN
θ value	0.125558 (rank : 1117)	NC score	0.023949 (rank : 1573)
Query Neighborhood Hits	1959	Target Neighborhood Hits	723	Shared Neighborhood Hits	116
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

CSKI1_HUMAN
θ value	0.125558 (rank : 1118)	NC score	0.051513 (rank : 1342)
Query Neighborhood Hits	1959	Target Neighborhood Hits	997	Shared Neighborhood Hits	362
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CUTL2_HUMAN
θ value	0.125558 (rank : 1119)	NC score	0.023614 (rank : 1581)
Query Neighborhood Hits	1959	Target Neighborhood Hits	906	Shared Neighborhood Hits	188
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

DPOD3_HUMAN
θ value	0.125558 (rank : 1120)	NC score	0.021082 (rank : 1626)
Query Neighborhood Hits	1959	Target Neighborhood Hits	109	Shared Neighborhood Hits	41
SwissProt Accessions	Q15054	Gene names	POLD3, KIAA0039
Domain Architecture	No domain graphic available
Description	DNA polymerase subunit delta 3 (DNA polymerase subunit delta p66).

ESAM_HUMAN
θ value	0.125558 (rank : 1121)	NC score	0.197858 (rank : 1010)
Query Neighborhood Hits	1959	Target Neighborhood Hits	251	Shared Neighborhood Hits	195
SwissProt Accessions	Q96AP7, Q96T50	Gene names	ESAM
Domain Architecture	No domain graphic available
Description	Endothelial cell-selective adhesion molecule precursor.

ESAM_MOUSE
θ value	0.125558 (rank : 1122)	NC score	0.178966 (rank : 1023)
Query Neighborhood Hits	1959	Target Neighborhood Hits	222	Shared Neighborhood Hits	173
SwissProt Accessions	Q925F2	Gene names	Esam, Esam1
Domain Architecture	No domain graphic available
Description	Endothelial cell-selective adhesion molecule precursor.

JPH2_HUMAN
θ value	0.125558 (rank : 1123)	NC score	0.055227 (rank : 1316)
Query Neighborhood Hits	1959	Target Neighborhood Hits	639	Shared Neighborhood Hits	297
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

K1802_HUMAN
θ value	0.125558 (rank : 1124)	NC score	0.041205 (rank : 1432)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1378	Shared Neighborhood Hits	404
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

LRRN3_HUMAN
θ value	0.125558 (rank : 1125)	NC score	0.154394 (rank : 1051)
Query Neighborhood Hits	1959	Target Neighborhood Hits	461	Shared Neighborhood Hits	221
SwissProt Accessions	Q9H3W5, O43377, Q6I9V8, Q8IYQ6	Gene names	LRRN3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 3 precursor (Neuronal leucine- rich repeat protein 3) (NLRR-3).

MISS_MOUSE
θ value	0.125558 (rank : 1126)	NC score	0.052763 (rank : 1329)
Query Neighborhood Hits	1959	Target Neighborhood Hits	444	Shared Neighborhood Hits	207
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

PRAX_HUMAN
θ value	0.125558 (rank : 1127)	NC score	0.050369 (rank : 1352)
Query Neighborhood Hits	1959	Target Neighborhood Hits	215	Shared Neighborhood Hits	94
SwissProt Accessions	Q9BXM0, Q9BXL9, Q9HCF2	Gene names	PRX, KIAA1620
Domain Architecture
Description	Periaxin.

PTN23_MOUSE
θ value	0.125558 (rank : 1128)	NC score	0.037270 (rank : 1460)
Query Neighborhood Hits	1959	Target Neighborhood Hits	726	Shared Neighborhood Hits	249
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

RTN1_MOUSE
θ value	0.125558 (rank : 1129)	NC score	0.026247 (rank : 1542)
Query Neighborhood Hits	1959	Target Neighborhood Hits	189	Shared Neighborhood Hits	95
SwissProt Accessions	Q8K0T0, Q8K4S4	Gene names	Rtn1, Nsp
Domain Architecture	No domain graphic available
Description	Reticulon-1 (Neuroendocrine-specific protein).

SFRIP_HUMAN
θ value	0.125558 (rank : 1130)	NC score	0.051980 (rank : 1339)
Query Neighborhood Hits	1959	Target Neighborhood Hits	530	Shared Neighborhood Hits	161
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

SON_MOUSE
θ value	0.125558 (rank : 1131)	NC score	0.065711 (rank : 1248)
Query Neighborhood Hits	1959	Target Neighborhood Hits	957	Shared Neighborhood Hits	351
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

UFO_HUMAN
θ value	0.125558 (rank : 1132)	NC score	0.671707 (rank : 678)
Query Neighborhood Hits	1959	Target Neighborhood Hits	981	Shared Neighborhood Hits	893
SwissProt Accessions	P30530	Gene names	AXL, UFO
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (AXL oncogene).

A1BG_HUMAN
θ value	0.163984 (rank : 1133)	NC score	0.055801 (rank : 1314)
Query Neighborhood Hits	1959	Target Neighborhood Hits	94	Shared Neighborhood Hits	44
SwissProt Accessions	P04217, Q8IYJ6, Q96P39	Gene names	A1BG
Domain Architecture
Description	Alpha-1B-glycoprotein precursor (Alpha-1-B glycoprotein).

AL2S2_HUMAN
θ value	0.163984 (rank : 1134)	NC score	0.723483 (rank : 586)
Query Neighborhood Hits	1959	Target Neighborhood Hits	727	Shared Neighborhood Hits	701
SwissProt Accessions	Q9C0K7, Q5BKY7, Q9P1L0	Gene names	ALS2CR2, ILPIP
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ALS2CR2 (EC 2.7.11.1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein) (ILP- interacting protein) (CALS-21).

ANPRA_MOUSE
θ value	0.163984 (rank : 1135)	NC score	0.412359 (rank : 833)
Query Neighborhood Hits	1959	Target Neighborhood Hits	600	Shared Neighborhood Hits	527
SwissProt Accessions	P18293	Gene names	Npr1, Npra
Domain Architecture
Description	Atrial natriuretic peptide receptor A precursor (ANP-A) (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor).

MLL2_HUMAN
θ value	0.163984 (rank : 1136)	NC score	0.060174 (rank : 1284)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1788	Shared Neighborhood Hits	475
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MYCB2_MOUSE
θ value	0.163984 (rank : 1137)	NC score	0.023786 (rank : 1576)
Query Neighborhood Hits	1959	Target Neighborhood Hits	307	Shared Neighborhood Hits	74
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

NPAS1_HUMAN
θ value	0.163984 (rank : 1138)	NC score	0.003484 (rank : 1906)
Query Neighborhood Hits	1959	Target Neighborhood Hits	77	Shared Neighborhood Hits	21
SwissProt Accessions	Q99742, Q99632, Q9BY83	Gene names	NPAS1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1) (Member of PAS protein 5) (MOP5).

NSD1_HUMAN
θ value	0.163984 (rank : 1139)	NC score	0.020713 (rank : 1634)
Query Neighborhood Hits	1959	Target Neighborhood Hits	427	Shared Neighborhood Hits	144
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

PDLI7_MOUSE
θ value	0.163984 (rank : 1140)	NC score	0.005777 (rank : 1876)
Query Neighborhood Hits	1959	Target Neighborhood Hits	279	Shared Neighborhood Hits	47
SwissProt Accessions	Q3TJD7, Q80ZY6, Q810S3, Q8C1S4, Q9CRA1	Gene names	Pdlim7, Enigma
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

PI3R4_HUMAN
θ value	0.163984 (rank : 1141)	NC score	0.349937 (rank : 912)
Query Neighborhood Hits	1959	Target Neighborhood Hits	534	Shared Neighborhood Hits	351
SwissProt Accessions	Q99570	Gene names	PIK3R4
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 4 (EC 2.7.11.1) (PI3- kinase regulatory subunit 4) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein).

PI3R4_MOUSE
θ value	0.163984 (rank : 1142)	NC score	0.364956 (rank : 896)
Query Neighborhood Hits	1959	Target Neighborhood Hits	535	Shared Neighborhood Hits	362
SwissProt Accessions	Q8VD65, Q56A65, Q8C948, Q8C9D7, Q9CVC5	Gene names	Pik3r4
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 4 (EC 2.7.11.1) (PI3- kinase regulatory subunit 4).

RERE_HUMAN
θ value	0.163984 (rank : 1143)	NC score	0.054964 (rank : 1318)
Query Neighborhood Hits	1959	Target Neighborhood Hits	779	Shared Neighborhood Hits	290
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

SC24C_HUMAN
θ value	0.163984 (rank : 1144)	NC score	0.048381 (rank : 1376)
Query Neighborhood Hits	1959	Target Neighborhood Hits	662	Shared Neighborhood Hits	270
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

SFPQ_HUMAN
θ value	0.163984 (rank : 1145)	NC score	0.057703 (rank : 1297)
Query Neighborhood Hits	1959	Target Neighborhood Hits	986	Shared Neighborhood Hits	274
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

SFRS8_HUMAN
θ value	0.163984 (rank : 1146)	NC score	0.039139 (rank : 1448)
Query Neighborhood Hits	1959	Target Neighborhood Hits	166	Shared Neighborhood Hits	67
SwissProt Accessions	Q12872	Gene names	SFRS8, SWAP
Domain Architecture
Description	Splicing factor, arginine/serine-rich 8 (Suppressor of white apricot protein homolog).

SPR1B_HUMAN
θ value	0.163984 (rank : 1147)	NC score	0.039706 (rank : 1445)
Query Neighborhood Hits	1959	Target Neighborhood Hits	102	Shared Neighborhood Hits	41
SwissProt Accessions	P22528, P22529, P22530, Q5T524	Gene names	SPRR1B
Domain Architecture	No domain graphic available
Description	Cornifin B (Small proline-rich protein IB) (SPR-IB) (14.9 kDa pancornulin).

STAP2_HUMAN
θ value	0.163984 (rank : 1148)	NC score	0.015614 (rank : 1708)
Query Neighborhood Hits	1959	Target Neighborhood Hits	29	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UGK3, Q9NXI2	Gene names	STAP2, BKS
Domain Architecture	No domain graphic available
Description	Signal-transducing adaptor protein 2 (STAP-2) (Breast tumor kinase substrate) (BRK substrate).

ASXL1_HUMAN
θ value	0.21417 (rank : 1149)	NC score	0.024728 (rank : 1566)
Query Neighborhood Hits	1959	Target Neighborhood Hits	260	Shared Neighborhood Hits	84
SwissProt Accessions	Q8IXJ9, Q5JWS9, Q8IYY7, Q9H466, Q9NQF8, Q9UFJ0, Q9UFP8, Q9Y2I4	Gene names	ASXL1, KIAA0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

BCAR1_MOUSE
θ value	0.21417 (rank : 1150)	NC score	0.038593 (rank : 1455)
Query Neighborhood Hits	1959	Target Neighborhood Hits	438	Shared Neighborhood Hits	189
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

CAC1H_MOUSE
θ value	0.21417 (rank : 1151)	NC score	0.005199 (rank : 1882)
Query Neighborhood Hits	1959	Target Neighborhood Hits	230	Shared Neighborhood Hits	83
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

CNOT3_HUMAN
θ value	0.21417 (rank : 1152)	NC score	0.045530 (rank : 1394)
Query Neighborhood Hits	1959	Target Neighborhood Hits	425	Shared Neighborhood Hits	131
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

ELOA2_HUMAN
θ value	0.21417 (rank : 1153)	NC score	0.025394 (rank : 1559)
Query Neighborhood Hits	1959	Target Neighborhood Hits	165	Shared Neighborhood Hits	59
SwissProt Accessions	Q8IYF1, Q9P2V9	Gene names	TCEB3B, TCEB3L
Domain Architecture
Description	RNA polymerase II transcription factor SIII subunit A2 (Elongin-A2) (EloA2) (Transcription elongation factor B polypeptide 3B).

FOXR1_HUMAN
θ value	0.21417 (rank : 1154)	NC score	0.000368 (rank : 1965)
Query Neighborhood Hits	1959	Target Neighborhood Hits	85	Shared Neighborhood Hits	13
SwissProt Accessions	Q6PIV2, Q86UT9, Q8IXX2	Gene names	FOXR1, DLNB13, FOXN5
Domain Architecture	No domain graphic available
Description	Forkhead box protein R1 (Forkhead box protein N5).

HCN2_HUMAN
θ value	0.21417 (rank : 1155)	NC score	0.025879 (rank : 1548)
Query Neighborhood Hits	1959	Target Neighborhood Hits	369	Shared Neighborhood Hits	156
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

IF4B_MOUSE
θ value	0.21417 (rank : 1156)	NC score	0.023266 (rank : 1588)
Query Neighborhood Hits	1959	Target Neighborhood Hits	368	Shared Neighborhood Hits	131
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

JPH3_HUMAN
θ value	0.21417 (rank : 1157)	NC score	0.012290 (rank : 1756)
Query Neighborhood Hits	1959	Target Neighborhood Hits	80	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WXH2, Q8N471, Q9HDC3, Q9HDC4	Gene names	JPH3, JP3
Domain Architecture
Description	Junctophilin-3 (Junctophilin type 3) (JP-3).

K0423_HUMAN
θ value	0.21417 (rank : 1158)	NC score	0.017613 (rank : 1672)
Query Neighborhood Hits	1959	Target Neighborhood Hits	171	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y4F4, Q68D66, Q6PG27	Gene names	KIAA0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

KIF17_HUMAN
θ value	0.21417 (rank : 1159)	NC score	0.002551 (rank : 1926)
Query Neighborhood Hits	1959	Target Neighborhood Hits	365	Shared Neighborhood Hits	67
SwissProt Accessions	Q9P2E2, O95077, Q53YS6, Q5VWA9, Q6GSA8, Q8N411	Gene names	KIF17, KIAA1405, KIF3X
Domain Architecture
Description	Kinesin-like protein KIF17 (KIF3-related motor protein).

LRRC4_MOUSE
θ value	0.21417 (rank : 1160)	NC score	0.093753 (rank : 1138)
Query Neighborhood Hits	1959	Target Neighborhood Hits	412	Shared Neighborhood Hits	175
SwissProt Accessions	Q99PH1, Q8VI35	Gene names	Lrrc4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing 4 protein precursor (Brain tumor- associated protein MBAG1).

LRRN3_MOUSE
θ value	0.21417 (rank : 1161)	NC score	0.146011 (rank : 1062)
Query Neighborhood Hits	1959	Target Neighborhood Hits	455	Shared Neighborhood Hits	221
SwissProt Accessions	Q8CBC6, P97860	Gene names	Lrrn3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 3 precursor (Neuronal leucine- rich repeat protein 3) (NLRR-3).

LZTS2_MOUSE
θ value	0.21417 (rank : 1162)	NC score	0.017513 (rank : 1676)
Query Neighborhood Hits	1959	Target Neighborhood Hits	423	Shared Neighborhood Hits	71
SwissProt Accessions	Q91YU6, Q569X6	Gene names	Lzts2, Kiaa1813
Domain Architecture
Description	Leucine zipper putative tumor suppressor 2.

MINT_MOUSE
θ value	0.21417 (rank : 1163)	NC score	0.062494 (rank : 1269)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1514	Shared Neighborhood Hits	433
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NCOR2_MOUSE
θ value	0.21417 (rank : 1164)	NC score	0.045219 (rank : 1396)
Query Neighborhood Hits	1959	Target Neighborhood Hits	790	Shared Neighborhood Hits	231
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

OBF1_HUMAN
θ value	0.21417 (rank : 1165)	NC score	0.042743 (rank : 1416)
Query Neighborhood Hits	1959	Target Neighborhood Hits	203	Shared Neighborhood Hits	117
SwissProt Accessions	Q16633, Q14983	Gene names	POU2AF1, OBF1
Domain Architecture	No domain graphic available
Description	POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (OCT-binding factor 1) (BOB-1) (OCA-B).

PKHA4_MOUSE
θ value	0.21417 (rank : 1166)	NC score	0.013996 (rank : 1731)
Query Neighborhood Hits	1959	Target Neighborhood Hits	202	Shared Neighborhood Hits	66
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PRGC2_MOUSE
θ value	0.21417 (rank : 1167)	NC score	0.020805 (rank : 1632)
Query Neighborhood Hits	1959	Target Neighborhood Hits	225	Shared Neighborhood Hits	67
SwissProt Accessions	Q8VHJ7, Q8C1C0	Gene names	Ppargc1b, Errl1, Pgc1, Pgc1b, Ppargc1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta protein) (PGC-1beta) (ERR ligand 1) (PPARGC-1-beta) (PGC-1-beta).

PRP2_MOUSE
θ value	0.21417 (rank : 1168)	NC score	0.084426 (rank : 1157)
Query Neighborhood Hits	1959	Target Neighborhood Hits	347	Shared Neighborhood Hits	175
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PSG8_HUMAN
θ value	0.21417 (rank : 1169)	NC score	0.175420 (rank : 1030)
Query Neighborhood Hits	1959	Target Neighborhood Hits	239	Shared Neighborhood Hits	194
SwissProt Accessions	Q9UQ74, O60410	Gene names	PSG8
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 8 precursor (PSBG-8).

SIX5_MOUSE
θ value	0.21417 (rank : 1170)	NC score	0.008254 (rank : 1820)
Query Neighborhood Hits	1959	Target Neighborhood Hits	354	Shared Neighborhood Hits	82
SwissProt Accessions	P70178	Gene names	Six5, Dmahp
Domain Architecture
Description	Homeobox protein SIX5 (DM locus-associated homeodomain protein homolog).

TP53B_MOUSE
θ value	0.21417 (rank : 1171)	NC score	0.052305 (rank : 1335)
Query Neighborhood Hits	1959	Target Neighborhood Hits	644	Shared Neighborhood Hits	217
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

ZAR1_HUMAN
θ value	0.21417 (rank : 1172)	NC score	0.042169 (rank : 1422)
Query Neighborhood Hits	1959	Target Neighborhood Hits	163	Shared Neighborhood Hits	73
SwissProt Accessions	Q86SH2	Gene names	ZAR1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

ZIMP7_HUMAN
θ value	0.21417 (rank : 1173)	NC score	0.014034 (rank : 1729)
Query Neighborhood Hits	1959	Target Neighborhood Hits	290	Shared Neighborhood Hits	91
SwissProt Accessions	Q8NF64, O94790, Q659A8, Q6JKL5, Q8WTX8, Q96Q01, Q9BQH7	Gene names	ZIMP7, KIAA1886
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

ZN692_MOUSE
θ value	0.21417 (rank : 1174)	NC score	-0.025147 (rank : 2105)
Query Neighborhood Hits	1959	Target Neighborhood Hits	751	Shared Neighborhood Hits	61
SwissProt Accessions	Q3U381	Gene names	Znf692, Zfp692
Domain Architecture	No domain graphic available
Description	Zinc finger protein 692.

APC_MOUSE
θ value	0.279714 (rank : 1175)	NC score	0.024149 (rank : 1572)
Query Neighborhood Hits	1959	Target Neighborhood Hits	441	Shared Neighborhood Hits	114
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

ARI1A_HUMAN
θ value	0.279714 (rank : 1176)	NC score	0.046231 (rank : 1387)
Query Neighborhood Hits	1959	Target Neighborhood Hits	787	Shared Neighborhood Hits	269
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

BMPR2_HUMAN
θ value	0.279714 (rank : 1177)	NC score	0.585223 (rank : 792)
Query Neighborhood Hits	1959	Target Neighborhood Hits	736	Shared Neighborhood Hits	697
SwissProt Accessions	Q13873, Q16569	Gene names	BMPR2, PPH1
Domain Architecture
Description	Bone morphogenetic protein receptor type-2 precursor (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II).

CG1_HUMAN
θ value	0.279714 (rank : 1178)	NC score	0.042356 (rank : 1420)
Query Neighborhood Hits	1959	Target Neighborhood Hits	222	Shared Neighborhood Hits	105
SwissProt Accessions	Q13495	Gene names	CXorf6, CG1
Domain Architecture	No domain graphic available
Description	CG1 protein (F18).

DNMBP_HUMAN
θ value	0.279714 (rank : 1179)	NC score	0.034326 (rank : 1479)
Query Neighborhood Hits	1959	Target Neighborhood Hits	413	Shared Neighborhood Hits	91
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

GPA33_HUMAN
θ value	0.279714 (rank : 1180)	NC score	0.208884 (rank : 1008)
Query Neighborhood Hits	1959	Target Neighborhood Hits	273	Shared Neighborhood Hits	182
SwissProt Accessions	Q99795	Gene names	GPA33
Domain Architecture
Description	Cell surface A33 antigen precursor (Glycoprotein A33).

IF4G3_MOUSE
θ value	0.279714 (rank : 1181)	NC score	0.014467 (rank : 1724)
Query Neighborhood Hits	1959	Target Neighborhood Hits	279	Shared Neighborhood Hits	83
SwissProt Accessions	Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0	Gene names	Eif4g3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

IRAK3_MOUSE
θ value	0.279714 (rank : 1182)	NC score	0.587285 (rank : 791)
Query Neighborhood Hits	1959	Target Neighborhood Hits	628	Shared Neighborhood Hits	597
SwissProt Accessions	Q8K4B2, Q8C7U8, Q8CE40, Q8K1S8	Gene names	Irak3
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1) (IRAK-3) (IL- 1 receptor-associated kinase M) (IRAK-M).

KI13B_HUMAN
θ value	0.279714 (rank : 1183)	NC score	0.001673 (rank : 1939)
Query Neighborhood Hits	1959	Target Neighborhood Hits	492	Shared Neighborhood Hits	103
SwissProt Accessions	Q9NQT8, O75134, Q9BYJ6	Gene names	KIF13B, GAKIN, KIAA0639
Domain Architecture
Description	Kinesin-like protein KIF13B (Kinesin-like protein GAKIN).

KLF12_HUMAN
θ value	0.279714 (rank : 1184)	NC score	-0.023533 (rank : 2097)
Query Neighborhood Hits	1959	Target Neighborhood Hits	717	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y4X4, Q5VZM7, Q9UHZ0	Gene names	KLF12, AP2REP
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 12 (Transcriptional repressor AP-2rep).

LR37A_HUMAN
θ value	0.279714 (rank : 1185)	NC score	0.058956 (rank : 1289)
Query Neighborhood Hits	1959	Target Neighborhood Hits	720	Shared Neighborhood Hits	270
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

LRC41_MOUSE
θ value	0.279714 (rank : 1186)	NC score	0.012212 (rank : 1757)
Query Neighborhood Hits	1959	Target Neighborhood Hits	37	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K1C9, Q91VX4	Gene names	Lrrc41, Muf1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 41 (Protein Muf1).

MLL4_HUMAN
θ value	0.279714 (rank : 1187)	NC score	0.042497 (rank : 1419)
Query Neighborhood Hits	1959	Target Neighborhood Hits	722	Shared Neighborhood Hits	277
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

MUCM_MOUSE
θ value	0.279714 (rank : 1188)	NC score	0.023265 (rank : 1589)
Query Neighborhood Hits	1959	Target Neighborhood Hits	242	Shared Neighborhood Hits	43
SwissProt Accessions	P01873	Gene names
Domain Architecture	No domain graphic available
Description	Ig mu chain C region membrane-bound form.

MUC_MOUSE
θ value	0.279714 (rank : 1189)	NC score	0.023732 (rank : 1577)
Query Neighborhood Hits	1959	Target Neighborhood Hits	242	Shared Neighborhood Hits	44
SwissProt Accessions	P01872	Gene names
Domain Architecture	No domain graphic available
Description	Ig mu chain C region secreted form.

NUMA1_HUMAN
θ value	0.279714 (rank : 1190)	NC score	0.014515 (rank : 1723)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1523	Shared Neighborhood Hits	177
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

PDLI7_HUMAN
θ value	0.279714 (rank : 1191)	NC score	0.020940 (rank : 1629)
Query Neighborhood Hits	1959	Target Neighborhood Hits	547	Shared Neighborhood Hits	193
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

PRR6_HUMAN
θ value	0.279714 (rank : 1192)	NC score	0.019128 (rank : 1651)
Query Neighborhood Hits	1959	Target Neighborhood Hits	39	Shared Neighborhood Hits	25
SwissProt Accessions	Q7Z7K6, Q3L8N5, Q8NFH6	Gene names	PRR6
Domain Architecture	No domain graphic available
Description	Proline-rich protein 6 (Nuclear protein p30).

PTN23_HUMAN
θ value	0.279714 (rank : 1193)	NC score	0.033305 (rank : 1488)
Query Neighborhood Hits	1959	Target Neighborhood Hits	646	Shared Neighborhood Hits	206
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

RN5A_MOUSE
θ value	0.279714 (rank : 1194)	NC score	0.313898 (rank : 933)
Query Neighborhood Hits	1959	Target Neighborhood Hits	899	Shared Neighborhood Hits	617
SwissProt Accessions	Q05921, Q9ERU7	Gene names	Rnasel, Rns4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

RUNX2_HUMAN
θ value	0.279714 (rank : 1195)	NC score	0.016864 (rank : 1692)
Query Neighborhood Hits	1959	Target Neighborhood Hits	103	Shared Neighborhood Hits	50
SwissProt Accessions	Q13950, O14614, O14615, O95181	Gene names	RUNX2, AML3, CBFA1, OSF2, PEBP2A
Domain Architecture
Description	Runt-related transcription factor 2 (Core-binding factor, alpha 1 subunit) (CBF-alpha 1) (Acute myeloid leukemia 3 protein) (Oncogene AML-3) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEBP2-alpha A) (PEA2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit) (Osteoblast- specific transcription factor 2) (OSF-2).

RUNX2_MOUSE
θ value	0.279714 (rank : 1196)	NC score	0.015767 (rank : 1705)
Query Neighborhood Hits	1959	Target Neighborhood Hits	119	Shared Neighborhood Hits	54
SwissProt Accessions	Q08775, O35183, Q08776, Q9JLN0, Q9QUQ6, Q9QY29, Q9R0U4, Q9Z2J7	Gene names	Runx2, Aml3, Cbfa1, Osf2, Pebp2a
Domain Architecture
Description	Runt-related transcription factor 2 (Core-binding factor, alpha 1 subunit) (CBF-alpha 1) (Acute myeloid leukemia 3 protein) (Oncogene AML-3) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEBP2-alpha A) (PEA2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit) (Osteoblast- specific transcription factor 2) (OSF-2).

SEM6B_MOUSE
θ value	0.279714 (rank : 1197)	NC score	0.001464 (rank : 1943)
Query Neighborhood Hits	1959	Target Neighborhood Hits	200	Shared Neighborhood Hits	69
SwissProt Accessions	O54951	Gene names	Sema6b, Seman
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin VIB) (Sema VIB) (Semaphorin N) (Sema N).

USH2A_MOUSE
θ value	0.279714 (rank : 1198)	NC score	0.124055 (rank : 1086)
Query Neighborhood Hits	1959	Target Neighborhood Hits	626	Shared Neighborhood Hits	176
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

ZC3H3_HUMAN
θ value	0.279714 (rank : 1199)	NC score	0.013867 (rank : 1733)
Query Neighborhood Hits	1959	Target Neighborhood Hits	159	Shared Neighborhood Hits	53
SwissProt Accessions	Q8IXZ2, Q14163, Q8N4E2, Q9BUS4	Gene names	ZC3H3, KIAA0150, ZC3HDC3
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

ZN687_HUMAN
θ value	0.279714 (rank : 1200)	NC score	-0.008131 (rank : 2058)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1244	Shared Neighborhood Hits	265
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

AHTF1_MOUSE
θ value	0.365318 (rank : 1201)	NC score	0.021089 (rank : 1625)
Query Neighborhood Hits	1959	Target Neighborhood Hits	176	Shared Neighborhood Hits	69
SwissProt Accessions	Q8CJF7, Q8BVJ5, Q8VD55	Gene names	Ahctf1, Elys
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

ARMX2_HUMAN
θ value	0.365318 (rank : 1202)	NC score	0.025370 (rank : 1560)
Query Neighborhood Hits	1959	Target Neighborhood Hits	134	Shared Neighborhood Hits	57
SwissProt Accessions	Q7L311, O60267, Q5H9D9	Gene names	ARMCX2, ALEX2, KIAA0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2 (Protein ALEX2) (ARM protein lost in epithelial cancers on chromosome X 2).

BASI_MOUSE
θ value	0.365318 (rank : 1203)	NC score	0.256332 (rank : 990)
Query Neighborhood Hits	1959	Target Neighborhood Hits	238	Shared Neighborhood Hits	201
SwissProt Accessions	P18572, Q6LDB0, Q7TSC0	Gene names	Bsg
Domain Architecture
Description	Basigin precursor (Basic immunoglobulin superfamily) (Membrane glycoprotein gp42) (HT7 antigen) (CD147 antigen).

CCD45_MOUSE
θ value	0.365318 (rank : 1204)	NC score	0.037610 (rank : 1457)
Query Neighborhood Hits	1959	Target Neighborhood Hits	663	Shared Neighborhood Hits	127
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

CT032_HUMAN
θ value	0.365318 (rank : 1205)	NC score	0.025287 (rank : 1561)
Query Neighborhood Hits	1959	Target Neighborhood Hits	235	Shared Neighborhood Hits	77
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

DNM3B_MOUSE
θ value	0.365318 (rank : 1206)	NC score	0.006046 (rank : 1868)
Query Neighborhood Hits	1959	Target Neighborhood Hits	61	Shared Neighborhood Hits	12
SwissProt Accessions	O88509, O88510, O88511	Gene names	Dnmt3b
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3B (EC 2.1.1.37) (Dnmt3b) (DNA methyltransferase MmuIIIB) (DNA MTase MmuIIIB) (M.MmuIIIB).

DVL3_MOUSE
θ value	0.365318 (rank : 1207)	NC score	0.006469 (rank : 1854)
Query Neighborhood Hits	1959	Target Neighborhood Hits	198	Shared Neighborhood Hits	46
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

EP300_HUMAN
θ value	0.365318 (rank : 1208)	NC score	0.050534 (rank : 1350)
Query Neighborhood Hits	1959	Target Neighborhood Hits	821	Shared Neighborhood Hits	327
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

EPHB6_MOUSE
θ value	0.365318 (rank : 1209)	NC score	0.566189 (rank : 801)
Query Neighborhood Hits	1959	Target Neighborhood Hits	906	Shared Neighborhood Hits	778
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

ETV3_HUMAN
θ value	0.365318 (rank : 1210)	NC score	0.018192 (rank : 1665)
Query Neighborhood Hits	1959	Target Neighborhood Hits	312	Shared Neighborhood Hits	122
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

FINC_HUMAN
θ value	0.365318 (rank : 1211)	NC score	0.151216 (rank : 1057)
Query Neighborhood Hits	1959	Target Neighborhood Hits	302	Shared Neighborhood Hits	149
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

GA2L1_MOUSE
θ value	0.365318 (rank : 1212)	NC score	0.025735 (rank : 1552)
Query Neighborhood Hits	1959	Target Neighborhood Hits	114	Shared Neighborhood Hits	54
SwissProt Accessions	Q8JZP9, Q5SVG0, Q8K573	Gene names	Gas2l1
Domain Architecture	No domain graphic available
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1).

GORS2_MOUSE
θ value	0.365318 (rank : 1213)	NC score	0.016076 (rank : 1699)
Query Neighborhood Hits	1959	Target Neighborhood Hits	89	Shared Neighborhood Hits	46
SwissProt Accessions	Q99JX3, Q3U9D2, Q8CCD0, Q91W68	Gene names	Gorasp2
Domain Architecture	No domain graphic available
Description	Golgi reassembly-stacking protein 2 (GRS2) (Golgi reassembly-stacking protein of 55 kDa) (GRASP55).

HRSL5_HUMAN
θ value	0.365318 (rank : 1214)	NC score	0.010862 (rank : 1778)
Query Neighborhood Hits	1959	Target Neighborhood Hits	26	Shared Neighborhood Hits	11
SwissProt Accessions	Q96KN8	Gene names	HRASLS5, HRLP5
Domain Architecture
Description	HRAS-like suppressor 5 (H-rev107-like protein 5).

HXB4_HUMAN
θ value	0.365318 (rank : 1215)	NC score	-0.010864 (rank : 2068)
Query Neighborhood Hits	1959	Target Neighborhood Hits	376	Shared Neighborhood Hits	59
SwissProt Accessions	P17483, Q9NTA0	Gene names	HOXB4, HOX2F
Domain Architecture
Description	Homeobox protein Hox-B4 (Hox-2F) (Hox-2.6).

IWS1_HUMAN
θ value	0.365318 (rank : 1216)	NC score	0.050340 (rank : 1353)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1241	Shared Neighborhood Hits	301
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

JHD3B_MOUSE
θ value	0.365318 (rank : 1217)	NC score	0.010318 (rank : 1786)
Query Neighborhood Hits	1959	Target Neighborhood Hits	152	Shared Neighborhood Hits	67
SwissProt Accessions	Q91VY5, Q3UR22, Q6ZQ30, Q99K42	Gene names	Jmjd2b, Jhdm3b
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

KLD8B_MOUSE
θ value	0.365318 (rank : 1218)	NC score	-0.001850 (rank : 2000)
Query Neighborhood Hits	1959	Target Neighborhood Hits	80	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D2D9	Gene names	Klhdc8b
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 8B.

KS6C1_HUMAN
θ value	0.365318 (rank : 1219)	NC score	0.663119 (rank : 700)
Query Neighborhood Hits	1959	Target Neighborhood Hits	682	Shared Neighborhood Hits	636
SwissProt Accessions	Q96S38, Q8TDD3, Q9NSF4, Q9UL66	Gene names	RPS6KC1, RPK118
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase delta-1 (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase) (Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein) (SPHK1-binding protein).

LRRN1_MOUSE
θ value	0.365318 (rank : 1220)	NC score	0.144749 (rank : 1064)
Query Neighborhood Hits	1959	Target Neighborhood Hits	508	Shared Neighborhood Hits	247
SwissProt Accessions	Q61809, Q3USY1, Q69ZI0	Gene names	Lrrn1, Kiaa1497
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 1 precursor (Neuronal leucine- rich repeat protein 1) (NLRR-1).

MEF2A_HUMAN
θ value	0.365318 (rank : 1221)	NC score	0.009420 (rank : 1799)
Query Neighborhood Hits	1959	Target Neighborhood Hits	69	Shared Neighborhood Hits	25
SwissProt Accessions	Q02078, O43814, Q14223, Q14224, Q96D14	Gene names	MEF2A, MEF2
Domain Architecture
Description	Myocyte-specific enhancer factor 2A (Serum response factor-like protein 1).

MEF2D_MOUSE
θ value	0.365318 (rank : 1222)	NC score	0.011798 (rank : 1763)
Query Neighborhood Hits	1959	Target Neighborhood Hits	146	Shared Neighborhood Hits	68
SwissProt Accessions	Q63943, Q63944	Gene names	Mef2d
Domain Architecture
Description	Myocyte-specific enhancer factor 2D.

MFA3L_MOUSE
θ value	0.365318 (rank : 1223)	NC score	0.228006 (rank : 1002)
Query Neighborhood Hits	1959	Target Neighborhood Hits	214	Shared Neighborhood Hits	196
SwissProt Accessions	Q9D3X9, Q80TV6, Q8BJA9	Gene names	Mfap3l, Kiaa0626
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 3-like precursor.

MILK2_HUMAN
θ value	0.365318 (rank : 1224)	NC score	0.027014 (rank : 1533)
Query Neighborhood Hits	1959	Target Neighborhood Hits	457	Shared Neighborhood Hits	156
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

MINT_HUMAN
θ value	0.365318 (rank : 1225)	NC score	0.049841 (rank : 1363)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1291	Shared Neighborhood Hits	354
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MUC18_HUMAN
θ value	0.365318 (rank : 1226)	NC score	0.288312 (rank : 957)
Query Neighborhood Hits	1959	Target Neighborhood Hits	275	Shared Neighborhood Hits	221
SwissProt Accessions	P43121, O95812, Q59E86, Q6PHR3, Q6ZTR2	Gene names	MCAM, MUC18
Domain Architecture
Description	Cell surface glycoprotein MUC18 precursor (Melanoma-associated antigen MUC18) (Melanoma cell adhesion molecule) (Melanoma-associated antigen A32) (S-endo 1 endothelial-associated antigen) (Cell surface glycoprotein P1H12) (CD146 antigen).

MUCDL_HUMAN
θ value	0.365318 (rank : 1227)	NC score	0.042240 (rank : 1421)
Query Neighborhood Hits	1959	Target Neighborhood Hits	777	Shared Neighborhood Hits	293
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

NPAS4_HUMAN
θ value	0.365318 (rank : 1228)	NC score	0.023277 (rank : 1587)
Query Neighborhood Hits	1959	Target Neighborhood Hits	214	Shared Neighborhood Hits	88
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

PSG2_HUMAN
θ value	0.365318 (rank : 1229)	NC score	0.163591 (rank : 1038)
Query Neighborhood Hits	1959	Target Neighborhood Hits	229	Shared Neighborhood Hits	189
SwissProt Accessions	P11465, Q8TCD9, Q9UEA4, Q9UQ78	Gene names	PSG2
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 2 precursor (PSBG-2) (Pregnancy-specific beta-1 glycoprotein E) (PS-beta-E).

PSG5_HUMAN
θ value	0.365318 (rank : 1230)	NC score	0.151410 (rank : 1056)
Query Neighborhood Hits	1959	Target Neighborhood Hits	231	Shared Neighborhood Hits	188
SwissProt Accessions	Q15238, Q15239, Q96QJ1, Q9UQ75	Gene names	PSG5
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 5 precursor (PSBG-5) (Fetal liver non-specific cross-reactive antigen 3) (FL-NCA-3).

RAPH1_HUMAN
θ value	0.365318 (rank : 1231)	NC score	0.056104 (rank : 1312)
Query Neighborhood Hits	1959	Target Neighborhood Hits	593	Shared Neighborhood Hits	266
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

RECQ4_HUMAN
θ value	0.365318 (rank : 1232)	NC score	0.006933 (rank : 1842)
Query Neighborhood Hits	1959	Target Neighborhood Hits	177	Shared Neighborhood Hits	51
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

RFX1_HUMAN
θ value	0.365318 (rank : 1233)	NC score	0.032868 (rank : 1492)
Query Neighborhood Hits	1959	Target Neighborhood Hits	256	Shared Neighborhood Hits	137
SwissProt Accessions	P22670	Gene names	RFX1
Domain Architecture
Description	MHC class II regulatory factor RFX1 (RFX) (Enhancer factor C) (EF-C).

RNF25_HUMAN
θ value	0.365318 (rank : 1234)	NC score	0.021429 (rank : 1621)
Query Neighborhood Hits	1959	Target Neighborhood Hits	163	Shared Neighborhood Hits	66
SwissProt Accessions	Q96BH1, Q9H874	Gene names	RNF25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-).

SALL3_HUMAN
θ value	0.365318 (rank : 1235)	NC score	-0.015076 (rank : 2087)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1066	Shared Neighborhood Hits	200
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

SFPQ_MOUSE
θ value	0.365318 (rank : 1236)	NC score	0.050174 (rank : 1356)
Query Neighborhood Hits	1959	Target Neighborhood Hits	958	Shared Neighborhood Hits	271
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

SNIP_MOUSE
θ value	0.365318 (rank : 1237)	NC score	0.025817 (rank : 1550)
Query Neighborhood Hits	1959	Target Neighborhood Hits	319	Shared Neighborhood Hits	96
SwissProt Accessions	Q9QWI6, O70298	Gene names	P140, Kiaa1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

SYNJ1_HUMAN
θ value	0.365318 (rank : 1238)	NC score	0.041282 (rank : 1429)
Query Neighborhood Hits	1959	Target Neighborhood Hits	498	Shared Neighborhood Hits	242
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

TENN_HUMAN
θ value	0.365318 (rank : 1239)	NC score	0.066335 (rank : 1244)
Query Neighborhood Hits	1959	Target Neighborhood Hits	453	Shared Neighborhood Hits	118
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TJAP1_HUMAN
θ value	0.365318 (rank : 1240)	NC score	0.018489 (rank : 1663)
Query Neighborhood Hits	1959	Target Neighborhood Hits	214	Shared Neighborhood Hits	43
SwissProt Accessions	Q5JTD0, Q5JTD1, Q5JWW1, Q68DB2, Q6P2P3, Q9H7V7	Gene names	TJAP1, PILT, TJP4
Domain Architecture	No domain graphic available
Description	Tight junction-associated protein 1 (Tight junction protein 4) (Protein incorporated later into tight junctions).

TXND2_MOUSE
θ value	0.365318 (rank : 1241)	NC score	0.031819 (rank : 1500)
Query Neighborhood Hits	1959	Target Neighborhood Hits	828	Shared Neighborhood Hits	166
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

WASIP_MOUSE
θ value	0.365318 (rank : 1242)	NC score	0.074444 (rank : 1192)
Query Neighborhood Hits	1959	Target Neighborhood Hits	392	Shared Neighborhood Hits	204
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

3BP1_HUMAN
θ value	0.47712 (rank : 1243)	NC score	0.023012 (rank : 1596)
Query Neighborhood Hits	1959	Target Neighborhood Hits	376	Shared Neighborhood Hits	172
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

BPTF_HUMAN
θ value	0.47712 (rank : 1244)	NC score	0.028716 (rank : 1521)
Query Neighborhood Hits	1959	Target Neighborhood Hits	786	Shared Neighborhood Hits	201
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

CJ047_HUMAN
θ value	0.47712 (rank : 1245)	NC score	0.025503 (rank : 1557)
Query Neighborhood Hits	1959	Target Neighborhood Hits	164	Shared Neighborhood Hits	80
SwissProt Accessions	Q86WR7, Q5W0J9, Q5W0K0, Q5W0K1, Q5W0K2, Q6PJC8, Q8N317	Gene names	C10orf47
Domain Architecture	No domain graphic available
Description	Protein C10orf47.

CO039_MOUSE
θ value	0.47712 (rank : 1246)	NC score	0.062796 (rank : 1267)
Query Neighborhood Hits	1959	Target Neighborhood Hits	445	Shared Neighborhood Hits	229
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

CTDP1_HUMAN
θ value	0.47712 (rank : 1247)	NC score	0.034859 (rank : 1474)
Query Neighborhood Hits	1959	Target Neighborhood Hits	416	Shared Neighborhood Hits	190
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

DDX51_HUMAN
θ value	0.47712 (rank : 1248)	NC score	0.003737 (rank : 1903)
Query Neighborhood Hits	1959	Target Neighborhood Hits	332	Shared Neighborhood Hits	94
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DUS8_HUMAN
θ value	0.47712 (rank : 1249)	NC score	0.009113 (rank : 1805)
Query Neighborhood Hits	1959	Target Neighborhood Hits	161	Shared Neighborhood Hits	60
SwissProt Accessions	Q13202	Gene names	DUSP8, VH5
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase hVH-5).

FBSH_MOUSE
θ value	0.47712 (rank : 1250)	NC score	0.020410 (rank : 1639)
Query Neighborhood Hits	1959	Target Neighborhood Hits	52	Shared Neighborhood Hits	28
SwissProt Accessions	Q8R089	Gene names	Fbs1, Fbs
Domain Architecture	No domain graphic available
Description	Probable fibrosin-1 long transcript protein.

FYB_MOUSE
θ value	0.47712 (rank : 1251)	NC score	0.024456 (rank : 1569)
Query Neighborhood Hits	1959	Target Neighborhood Hits	194	Shared Neighborhood Hits	64
SwissProt Accessions	O35601, Q9Z2H3	Gene names	Fyb
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

GA2L2_MOUSE
θ value	0.47712 (rank : 1252)	NC score	0.041087 (rank : 1434)
Query Neighborhood Hits	1959	Target Neighborhood Hits	395	Shared Neighborhood Hits	200
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

GAB1_MOUSE
θ value	0.47712 (rank : 1253)	NC score	0.021709 (rank : 1614)
Query Neighborhood Hits	1959	Target Neighborhood Hits	233	Shared Neighborhood Hits	92
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

GAK4_HUMAN
θ value	0.47712 (rank : 1254)	NC score	0.021745 (rank : 1613)
Query Neighborhood Hits	1959	Target Neighborhood Hits	415	Shared Neighborhood Hits	191
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

H13_MOUSE
θ value	0.47712 (rank : 1255)	NC score	0.014782 (rank : 1720)
Query Neighborhood Hits	1959	Target Neighborhood Hits	81	Shared Neighborhood Hits	36
SwissProt Accessions	P43277, Q8C6M4	Gene names	Hist1h1d, H1f3
Domain Architecture
Description	Histone H1.3 (H1 VAR.4) (H1d).

HCFC2_HUMAN
θ value	0.47712 (rank : 1256)	NC score	0.074422 (rank : 1193)
Query Neighborhood Hits	1959	Target Neighborhood Hits	154	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Y5Z7	Gene names	HCFC2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

HORN_MOUSE
θ value	0.47712 (rank : 1257)	NC score	0.003056 (rank : 1916)
Query Neighborhood Hits	1959	Target Neighborhood Hits	218	Shared Neighborhood Hits	43
SwissProt Accessions	Q8VHD8	Gene names	Hrnr
Domain Architecture
Description	Hornerin.

INVS_MOUSE
θ value	0.47712 (rank : 1258)	NC score	0.021487 (rank : 1618)
Query Neighborhood Hits	1959	Target Neighborhood Hits	609	Shared Neighborhood Hits	178
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

KS6C1_MOUSE
θ value	0.47712 (rank : 1259)	NC score	0.666797 (rank : 687)
Query Neighborhood Hits	1959	Target Neighborhood Hits	700	Shared Neighborhood Hits	637
SwissProt Accessions	Q8BLK9, Q3UDY3, Q6PDY4, Q8BMQ5, Q8BX49	Gene names	Rps6kc1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase delta-1 (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase).

LAD1_MOUSE
θ value	0.47712 (rank : 1260)	NC score	0.067235 (rank : 1236)
Query Neighborhood Hits	1959	Target Neighborhood Hits	391	Shared Neighborhood Hits	164
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

LDB3_MOUSE
θ value	0.47712 (rank : 1261)	NC score	0.020106 (rank : 1641)
Query Neighborhood Hits	1959	Target Neighborhood Hits	510	Shared Neighborhood Hits	171
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

LEUK_HUMAN
θ value	0.47712 (rank : 1262)	NC score	0.038401 (rank : 1456)
Query Neighborhood Hits	1959	Target Neighborhood Hits	213	Shared Neighborhood Hits	87
SwissProt Accessions	P16150	Gene names	SPN, CD43
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Galactoglycoprotein) (GALGP) (CD43 antigen).

LPP_HUMAN
θ value	0.47712 (rank : 1263)	NC score	0.040674 (rank : 1437)
Query Neighborhood Hits	1959	Target Neighborhood Hits	775	Shared Neighborhood Hits	286
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

MYST3_MOUSE
θ value	0.47712 (rank : 1264)	NC score	0.012093 (rank : 1759)
Query Neighborhood Hits	1959	Target Neighborhood Hits	688	Shared Neighborhood Hits	171
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

PSG9_HUMAN
θ value	0.47712 (rank : 1265)	NC score	0.154526 (rank : 1050)
Query Neighborhood Hits	1959	Target Neighborhood Hits	221	Shared Neighborhood Hits	186
SwissProt Accessions	Q00887, Q15236, Q15237, Q8WW78, Q9UQ73	Gene names	PSG9, PSG11
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 9 precursor (PSBG-9) (Pregnancy-specific glycoprotein 9) (Pregnancy-specific beta-1 glycoprotein B) (PS-beta-B) (PS34) (Pregnancy-specific glycoprotein 7) (PSG7).

PVRL3_HUMAN
θ value	0.47712 (rank : 1266)	NC score	0.138620 (rank : 1069)
Query Neighborhood Hits	1959	Target Neighborhood Hits	204	Shared Neighborhood Hits	142
SwissProt Accessions	Q9NQS3, Q6NVZ3, Q8WVU4, Q9BVA9, Q9Y412	Gene names	PVRL3, PRR3
Domain Architecture	No domain graphic available
Description	Poliovirus receptor-related protein 3 precursor (Nectin-3) (CDw113 antigen).

SELPL_MOUSE
θ value	0.47712 (rank : 1267)	NC score	0.072321 (rank : 1208)
Query Neighborhood Hits	1959	Target Neighborhood Hits	588	Shared Neighborhood Hits	269
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SYP2L_HUMAN
θ value	0.47712 (rank : 1268)	NC score	0.037409 (rank : 1459)
Query Neighborhood Hits	1959	Target Neighborhood Hits	400	Shared Neighborhood Hits	173
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

T22D4_MOUSE
θ value	0.47712 (rank : 1269)	NC score	0.022774 (rank : 1602)
Query Neighborhood Hits	1959	Target Neighborhood Hits	92	Shared Neighborhood Hits	50
SwissProt Accessions	Q9EQN3	Gene names	Tsc22d4, Tilz2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2).

TAF3_MOUSE
θ value	0.47712 (rank : 1270)	NC score	0.042742 (rank : 1417)
Query Neighborhood Hits	1959	Target Neighborhood Hits	463	Shared Neighborhood Hits	122
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TARA_MOUSE
θ value	0.47712 (rank : 1271)	NC score	0.052038 (rank : 1338)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1133	Shared Neighborhood Hits	325
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TAU_MOUSE
θ value	0.47712 (rank : 1272)	NC score	0.053263 (rank : 1327)
Query Neighborhood Hits	1959	Target Neighborhood Hits	502	Shared Neighborhood Hits	225
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TITF1_MOUSE
θ value	0.47712 (rank : 1273)	NC score	-0.007753 (rank : 2056)
Query Neighborhood Hits	1959	Target Neighborhood Hits	335	Shared Neighborhood Hits	31
SwissProt Accessions	P50220	Gene names	Titf1, Nkx-2.1, Nkx2-1, Ttf1
Domain Architecture	No domain graphic available
Description	Thyroid transcription factor 1 (Thyroid nuclear factor 1) (TTF-1) (Homeobox protein Nkx-2.1).

TJAP1_MOUSE
θ value	0.47712 (rank : 1274)	NC score	0.019430 (rank : 1648)
Query Neighborhood Hits	1959	Target Neighborhood Hits	295	Shared Neighborhood Hits	51
SwissProt Accessions	Q9DCD5, Q8CFL7, Q8R5I2	Gene names	Tjap1, Pilt, Tjp4
Domain Architecture	No domain graphic available
Description	Tight junction-associated protein 1 (Tight junction protein 4) (Protein incorporated later into tight junctions).

TM108_MOUSE
θ value	0.47712 (rank : 1275)	NC score	0.039470 (rank : 1446)
Query Neighborhood Hits	1959	Target Neighborhood Hits	336	Shared Neighborhood Hits	158
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

TMPSD_HUMAN
θ value	0.47712 (rank : 1276)	NC score	-0.005467 (rank : 2041)
Query Neighborhood Hits	1959	Target Neighborhood Hits	333	Shared Neighborhood Hits	72
SwissProt Accessions	Q9BYE2, Q86YM4, Q96JY8, Q9BYE1	Gene names	TMPRSS13, MSP, TMPRSS11
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

TULP4_MOUSE
θ value	0.47712 (rank : 1277)	NC score	0.023250 (rank : 1590)
Query Neighborhood Hits	1959	Target Neighborhood Hits	247	Shared Neighborhood Hits	68
SwissProt Accessions	Q9JIL5, Q8CA75, Q922C2	Gene names	Tulp4, Tusp
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

UNC5B_HUMAN
θ value	0.47712 (rank : 1278)	NC score	0.115115 (rank : 1105)
Query Neighborhood Hits	1959	Target Neighborhood Hits	225	Shared Neighborhood Hits	138
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

UNC5B_MOUSE
θ value	0.47712 (rank : 1279)	NC score	0.112566 (rank : 1107)
Query Neighborhood Hits	1959	Target Neighborhood Hits	226	Shared Neighborhood Hits	139
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

XRCC1_HUMAN
θ value	0.47712 (rank : 1280)	NC score	0.027897 (rank : 1528)
Query Neighborhood Hits	1959	Target Neighborhood Hits	131	Shared Neighborhood Hits	51
SwissProt Accessions	P18887, Q9HCB1	Gene names	XRCC1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

ZN335_HUMAN
θ value	0.47712 (rank : 1281)	NC score	-0.023699 (rank : 2099)
Query Neighborhood Hits	1959	Target Neighborhood Hits	973	Shared Neighborhood Hits	127
SwissProt Accessions	Q9H4Z2, Q9H684	Gene names	ZNF335
Domain Architecture	No domain graphic available
Description	Zinc finger protein 335.

ACV1C_MOUSE
θ value	0.62314 (rank : 1282)	NC score	0.540637 (rank : 806)
Query Neighborhood Hits	1959	Target Neighborhood Hits	715	Shared Neighborhood Hits	689
SwissProt Accessions	Q8K348	Gene names	Acvr1c, Alk7
Domain Architecture	No domain graphic available
Description	Activin receptor type 1C precursor (EC 2.7.11.30) (ACTR-IC) (Activin receptor-like kinase 7) (ALK-7).

AMGO3_HUMAN
θ value	0.62314 (rank : 1283)	NC score	0.047706 (rank : 1380)
Query Neighborhood Hits	1959	Target Neighborhood Hits	276	Shared Neighborhood Hits	84
SwissProt Accessions	Q86WK7, Q96JH6	Gene names	AMIGO3, ALI3, KIAA1851
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 3 precursor (AMIGO-3) (Alivin-3).

ANGL6_MOUSE
θ value	0.62314 (rank : 1284)	NC score	-0.002606 (rank : 2009)
Query Neighborhood Hits	1959	Target Neighborhood Hits	63	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R0Z6	Gene names	Angptl6, Agf
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 6 precursor (Angiopoietin-like 6) (Angiopoietin-related growth factor).

ASPP1_MOUSE
θ value	0.62314 (rank : 1285)	NC score	0.051409 (rank : 1343)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1244	Shared Neighborhood Hits	341
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

CBL_HUMAN
θ value	0.62314 (rank : 1286)	NC score	0.014362 (rank : 1725)
Query Neighborhood Hits	1959	Target Neighborhood Hits	353	Shared Neighborhood Hits	96
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CF150_HUMAN
θ value	0.62314 (rank : 1287)	NC score	0.034163 (rank : 1480)
Query Neighborhood Hits	1959	Target Neighborhood Hits	96	Shared Neighborhood Hits	50
SwissProt Accessions	Q8N884, Q32NC9, Q5SWL0, Q5SWL1, Q96E45	Gene names	C6orf150
Domain Architecture	No domain graphic available
Description	Protein C6orf150.

DOS_HUMAN
θ value	0.62314 (rank : 1288)	NC score	0.017466 (rank : 1679)
Query Neighborhood Hits	1959	Target Neighborhood Hits	68	Shared Neighborhood Hits	26
SwissProt Accessions	Q8N350, O43385	Gene names	DOS, C19orf26
Domain Architecture	No domain graphic available
Description	Protein Dos.

EVC_MOUSE
θ value	0.62314 (rank : 1289)	NC score	0.011976 (rank : 1761)
Query Neighborhood Hits	1959	Target Neighborhood Hits	80	Shared Neighborhood Hits	13
SwissProt Accessions	P57680	Gene names	Evc
Domain Architecture	No domain graphic available
Description	Ellis-van Creveld syndrome protein homolog.

FCRLA_MOUSE
θ value	0.62314 (rank : 1290)	NC score	0.056234 (rank : 1309)
Query Neighborhood Hits	1959	Target Neighborhood Hits	110	Shared Neighborhood Hits	62
SwissProt Accessions	Q920A9, Q3T9Q2, Q8K3U9, Q8VHP5	Gene names	Fcrla, Fcrl, Fcrl1, Fcrlm1, Fcrx, Freb
Domain Architecture	No domain graphic available
Description	Fc receptor-like and mucin-like 1 precursor (Fc receptor-like A) (Fc receptor homolog expressed in B-cells) (Fc receptor-related protein X) (FcRX) (Fc receptor-like protein).

GAB1_HUMAN
θ value	0.62314 (rank : 1291)	NC score	0.025276 (rank : 1562)
Query Neighborhood Hits	1959	Target Neighborhood Hits	279	Shared Neighborhood Hits	124
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

HDAC7_HUMAN
θ value	0.62314 (rank : 1292)	NC score	0.004717 (rank : 1889)
Query Neighborhood Hits	1959	Target Neighborhood Hits	64	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WUI4, Q7Z5I1, Q96K01, Q9BR73, Q9H7L0, Q9NW41, Q9NWA9, Q9NYK9, Q9UFU7	Gene names	HDAC7A, HDAC7
Domain Architecture
Description	Histone deacetylase 7a (HD7a).

ILRL2_MOUSE
θ value	0.62314 (rank : 1293)	NC score	0.128829 (rank : 1077)
Query Neighborhood Hits	1959	Target Neighborhood Hits	158	Shared Neighborhood Hits	136
SwissProt Accessions	Q9ERS7	Gene names	Il1rl2
Domain Architecture
Description	Interleukin-1 receptor-like 2 precursor (IL-1Rrp2).

IRS2_HUMAN
θ value	0.62314 (rank : 1294)	NC score	0.034772 (rank : 1475)
Query Neighborhood Hits	1959	Target Neighborhood Hits	262	Shared Neighborhood Hits	131
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

JHD3B_HUMAN
θ value	0.62314 (rank : 1295)	NC score	0.005908 (rank : 1872)
Query Neighborhood Hits	1959	Target Neighborhood Hits	128	Shared Neighborhood Hits	43
SwissProt Accessions	O94953, O75274, Q6P3R5, Q9P1V1, Q9UF40	Gene names	JMJD2B, JHDM3B, KIAA0876
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

K0423_MOUSE
θ value	0.62314 (rank : 1296)	NC score	0.012686 (rank : 1749)
Query Neighborhood Hits	1959	Target Neighborhood Hits	115	Shared Neighborhood Hits	27
SwissProt Accessions	Q6A070	Gene names	Kiaa0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

K1543_HUMAN
θ value	0.62314 (rank : 1297)	NC score	0.049574 (rank : 1365)
Query Neighborhood Hits	1959	Target Neighborhood Hits	435	Shared Neighborhood Hits	205
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

LRC24_MOUSE
θ value	0.62314 (rank : 1298)	NC score	0.120860 (rank : 1097)
Query Neighborhood Hits	1959	Target Neighborhood Hits	387	Shared Neighborhood Hits	191
SwissProt Accessions	Q8BHA1	Gene names	Lrrc24
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 24 precursor.

LRRN1_HUMAN
θ value	0.62314 (rank : 1299)	NC score	0.150309 (rank : 1059)
Query Neighborhood Hits	1959	Target Neighborhood Hits	518	Shared Neighborhood Hits	250
SwissProt Accessions	Q6UXK5, Q3LID5, Q8IYV5, Q9H8V1, Q9P231	Gene names	LRRN1, KIAA1497
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 1 precursor (Neuronal leucine- rich repeat protein 1) (NLRR-1).

MTF1_HUMAN
θ value	0.62314 (rank : 1300)	NC score	-0.025184 (rank : 2106)
Query Neighborhood Hits	1959	Target Neighborhood Hits	814	Shared Neighborhood Hits	99
SwissProt Accessions	Q14872, Q96CB1	Gene names	MTF1
Domain Architecture	No domain graphic available
Description	Metal-regulatory transcription factor 1 (Transcription factor MTF-1) (MRE-binding transcription factor).

NPAS4_MOUSE
θ value	0.62314 (rank : 1301)	NC score	0.026518 (rank : 1537)
Query Neighborhood Hits	1959	Target Neighborhood Hits	245	Shared Neighborhood Hits	107
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

PGCB_HUMAN
θ value	0.62314 (rank : 1302)	NC score	0.000062 (rank : 1973)
Query Neighborhood Hits	1959	Target Neighborhood Hits	478	Shared Neighborhood Hits	83
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

PI5PA_MOUSE
θ value	0.62314 (rank : 1303)	NC score	0.046996 (rank : 1383)
Query Neighborhood Hits	1959	Target Neighborhood Hits	331	Shared Neighborhood Hits	189
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

RERE_MOUSE
θ value	0.62314 (rank : 1304)	NC score	0.052356 (rank : 1334)
Query Neighborhood Hits	1959	Target Neighborhood Hits	785	Shared Neighborhood Hits	294
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

REXO1_HUMAN
θ value	0.62314 (rank : 1305)	NC score	0.026335 (rank : 1540)
Query Neighborhood Hits	1959	Target Neighborhood Hits	242	Shared Neighborhood Hits	104
SwissProt Accessions	Q8N1G1, Q9ULT2	Gene names	REXO1, ELOABP1, KIAA1138, TCEB3BP1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Elongin A-binding protein 1) (EloA-BP1) (Transcription elongation factor B polypeptide 3-binding protein 1).

SFR15_HUMAN
θ value	0.62314 (rank : 1306)	NC score	0.043036 (rank : 1414)
Query Neighborhood Hits	1959	Target Neighborhood Hits	368	Shared Neighborhood Hits	135
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

TAF6L_MOUSE
θ value	0.62314 (rank : 1307)	NC score	0.016765 (rank : 1693)
Query Neighborhood Hits	1959	Target Neighborhood Hits	146	Shared Neighborhood Hits	71
SwissProt Accessions	Q8R2K4, Q8C5T2	Gene names	Taf6l, Paf65a
Domain Architecture
Description	TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (PCAF-associated factor 65 alpha) (PAF65- alpha).

TB182_HUMAN
θ value	0.62314 (rank : 1308)	NC score	0.043216 (rank : 1412)
Query Neighborhood Hits	1959	Target Neighborhood Hits	414	Shared Neighborhood Hits	139
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

TBX2_MOUSE
θ value	0.62314 (rank : 1309)	NC score	0.001180 (rank : 1951)
Query Neighborhood Hits	1959	Target Neighborhood Hits	97	Shared Neighborhood Hits	36
SwissProt Accessions	Q60707	Gene names	Tbx2
Domain Architecture
Description	T-box transcription factor TBX2 (T-box protein 2).

UNC5A_MOUSE
θ value	0.62314 (rank : 1310)	NC score	0.107177 (rank : 1116)
Query Neighborhood Hits	1959	Target Neighborhood Hits	203	Shared Neighborhood Hits	127
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

WWC1_HUMAN
θ value	0.62314 (rank : 1311)	NC score	0.009249 (rank : 1803)
Query Neighborhood Hits	1959	Target Neighborhood Hits	290	Shared Neighborhood Hits	46
SwissProt Accessions	Q8IX03, O94946, Q6MZX4, Q6Y2F8, Q7Z4G8, Q8WVM4, Q9BT29	Gene names	WWC1, KIAA0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA) (HBeAg-binding protein 3).

ALX4_HUMAN
θ value	0.813845 (rank : 1312)	NC score	-0.012483 (rank : 2075)
Query Neighborhood Hits	1959	Target Neighborhood Hits	394	Shared Neighborhood Hits	49
SwissProt Accessions	Q9H161, Q96JN7, Q9H198, Q9HAY9	Gene names	ALX4, KIAA1788
Domain Architecture
Description	Homeobox protein aristaless-like 4.

ARHG1_MOUSE
θ value	0.813845 (rank : 1313)	NC score	0.008018 (rank : 1824)
Query Neighborhood Hits	1959	Target Neighborhood Hits	266	Shared Neighborhood Hits	91
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

CBP_HUMAN
θ value	0.813845 (rank : 1314)	NC score	0.054957 (rank : 1319)
Query Neighborhood Hits	1959	Target Neighborhood Hits	941	Shared Neighborhood Hits	355
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CD166_MOUSE
θ value	0.813845 (rank : 1315)	NC score	0.225316 (rank : 1003)
Query Neighborhood Hits	1959	Target Neighborhood Hits	252	Shared Neighborhood Hits	188
SwissProt Accessions	Q61490, O70136, Q8CDA5, Q8R2T0	Gene names	Alcam
Domain Architecture
Description	CD166 antigen precursor (Activated leukocyte-cell adhesion molecule) (ALCAM) (DM-GRASP protein).

CE025_HUMAN
θ value	0.813845 (rank : 1316)	NC score	0.026443 (rank : 1538)
Query Neighborhood Hits	1959	Target Neighborhood Hits	114	Shared Neighborhood Hits	53
SwissProt Accessions	Q8NDZ2, Q6NXN8, Q6ZTU4, Q8IZ15	Gene names	C5orf25
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C5orf25.

CK024_MOUSE
θ value	0.813845 (rank : 1317)	NC score	0.050331 (rank : 1355)
Query Neighborhood Hits	1959	Target Neighborhood Hits	307	Shared Neighborhood Hits	140
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

CNTP1_MOUSE
θ value	0.813845 (rank : 1318)	NC score	0.008303 (rank : 1818)
Query Neighborhood Hits	1959	Target Neighborhood Hits	183	Shared Neighborhood Hits	32
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

CNTRB_MOUSE
θ value	0.813845 (rank : 1319)	NC score	0.040430 (rank : 1438)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1029	Shared Neighborhood Hits	188
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

CO039_HUMAN
θ value	0.813845 (rank : 1320)	NC score	0.048583 (rank : 1375)
Query Neighborhood Hits	1959	Target Neighborhood Hits	264	Shared Neighborhood Hits	143
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

CRTC1_MOUSE
θ value	0.813845 (rank : 1321)	NC score	0.032742 (rank : 1494)
Query Neighborhood Hits	1959	Target Neighborhood Hits	230	Shared Neighborhood Hits	117
SwissProt Accessions	Q68ED7, Q6ZQ85	Gene names	Crtc1, Kiaa0616, Mect1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1 homolog).

CSKI2_HUMAN
θ value	0.813845 (rank : 1322)	NC score	0.043004 (rank : 1415)
Query Neighborhood Hits	1959	Target Neighborhood Hits	747	Shared Neighborhood Hits	229
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

ENL_HUMAN
θ value	0.813845 (rank : 1323)	NC score	0.041853 (rank : 1425)
Query Neighborhood Hits	1959	Target Neighborhood Hits	305	Shared Neighborhood Hits	107
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

FNDC3_HUMAN
θ value	0.813845 (rank : 1324)	NC score	0.234008 (rank : 999)
Query Neighborhood Hits	1959	Target Neighborhood Hits	196	Shared Neighborhood Hits	133
SwissProt Accessions	Q9Y2H6, Q5JVF9, Q6EVH3, Q6N020, Q6P9D5, Q9H1W1	Gene names	FNDC3A, FNDC3, KIAA0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

FNDC3_MOUSE
θ value	0.813845 (rank : 1325)	NC score	0.234870 (rank : 998)
Query Neighborhood Hits	1959	Target Neighborhood Hits	207	Shared Neighborhood Hits	133
SwissProt Accessions	Q8BX90, Q2VEY7, Q6ZQ15, Q811D3, Q8BTM3	Gene names	Fndc3a, D14Ertd453e, Fndc3, Kiaa0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

FOSL2_MOUSE
θ value	0.813845 (rank : 1326)	NC score	0.005617 (rank : 1877)
Query Neighborhood Hits	1959	Target Neighborhood Hits	151	Shared Neighborhood Hits	22
SwissProt Accessions	P47930	Gene names	Fosl2, Fra-2, Fra2
Domain Architecture	No domain graphic available
Description	Fos-related antigen 2.

FOXL2_MOUSE
θ value	0.813845 (rank : 1327)	NC score	0.000083 (rank : 1972)
Query Neighborhood Hits	1959	Target Neighborhood Hits	151	Shared Neighborhood Hits	54
SwissProt Accessions	O88470, Q8K3X9	Gene names	Foxl2, Pfrk
Domain Architecture	No domain graphic available
Description	Forkhead box protein L2 (Pituitary forkhead factor) (P-Frk).

GAK12_HUMAN
θ value	0.813845 (rank : 1328)	NC score	0.019548 (rank : 1647)
Query Neighborhood Hits	1959	Target Neighborhood Hits	374	Shared Neighborhood Hits	169
SwissProt Accessions	P63130, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K102 Gag protein) (HERV-K(III) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK6_HUMAN
θ value	0.813845 (rank : 1329)	NC score	0.021967 (rank : 1610)
Query Neighborhood Hits	1959	Target Neighborhood Hits	392	Shared Neighborhood Hits	183
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

HCFC1_MOUSE
θ value	0.813845 (rank : 1330)	NC score	0.056609 (rank : 1307)
Query Neighborhood Hits	1959	Target Neighborhood Hits	348	Shared Neighborhood Hits	148
SwissProt Accessions	Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2	Gene names	Hcfc1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

HXD9_HUMAN
θ value	0.813845 (rank : 1331)	NC score	-0.010615 (rank : 2066)
Query Neighborhood Hits	1959	Target Neighborhood Hits	352	Shared Neighborhood Hits	32
SwissProt Accessions	P28356	Gene names	HOXD9, HOX4C
Domain Architecture
Description	Homeobox protein Hox-D9 (Hox-4C) (Hox-5.2).

IQEC3_HUMAN
θ value	0.813845 (rank : 1332)	NC score	0.004918 (rank : 1885)
Query Neighborhood Hits	1959	Target Neighborhood Hits	125	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UPP2, Q8TB43	Gene names	IQSEC3, KIAA1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

LAD1_HUMAN
θ value	0.813845 (rank : 1333)	NC score	0.060786 (rank : 1281)
Query Neighborhood Hits	1959	Target Neighborhood Hits	441	Shared Neighborhood Hits	174
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

LCP2_MOUSE
θ value	0.813845 (rank : 1334)	NC score	0.047582 (rank : 1381)
Query Neighborhood Hits	1959	Target Neighborhood Hits	177	Shared Neighborhood Hits	83
SwissProt Accessions	Q60787	Gene names	Lcp2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

LSM11_HUMAN
θ value	0.813845 (rank : 1335)	NC score	0.019738 (rank : 1644)
Query Neighborhood Hits	1959	Target Neighborhood Hits	16	Shared Neighborhood Hits	6
SwissProt Accessions	P83369, Q7Z7P0, Q8N975	Gene names	LSM11
Domain Architecture	No domain graphic available
Description	U7 snRNA-associated Sm-like protein LSm11.

MA1B1_HUMAN
θ value	0.813845 (rank : 1336)	NC score	0.011659 (rank : 1765)
Query Neighborhood Hits	1959	Target Neighborhood Hits	125	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UKM7, Q5VSG3, Q9BRS9, Q9Y5K7	Gene names	MAN1B1
Domain Architecture
Description	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (EC 3.2.1.113) (ER alpha-1,2-mannosidase) (Mannosidase alpha class 1B member 1) (Man9GlcNAc2-specific-processing alpha-mannosidase).

NFAC1_HUMAN
θ value	0.813845 (rank : 1337)	NC score	0.017542 (rank : 1675)
Query Neighborhood Hits	1959	Target Neighborhood Hits	312	Shared Neighborhood Hits	146
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

PDE9A_HUMAN
θ value	0.813845 (rank : 1338)	NC score	-0.004046 (rank : 2027)
Query Neighborhood Hits	1959	Target Neighborhood Hits	93	Shared Neighborhood Hits	5
SwissProt Accessions	O76083, O75490, O75491, O95225, Q86SF7, Q86SI6, Q86SJ3, Q86WN3, Q86WN4, Q86WN5, Q86WN6, Q86WN7, Q86WN8, Q86WN9, Q86WP0	Gene names	PDE9A
Domain Architecture
Description	High-affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (EC 3.1.4.35).

PDL1_HUMAN
θ value	0.813845 (rank : 1339)	NC score	0.121972 (rank : 1093)
Query Neighborhood Hits	1959	Target Neighborhood Hits	195	Shared Neighborhood Hits	132
SwissProt Accessions	Q9NZQ7, Q66RK1, Q6WEX4, Q9NUZ5	Gene names	CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

PDL2_MOUSE
θ value	0.813845 (rank : 1340)	NC score	0.110137 (rank : 1110)
Query Neighborhood Hits	1959	Target Neighborhood Hits	116	Shared Neighborhood Hits	90
SwissProt Accessions	Q9WUL5	Gene names	Pdcd1lg2, B7dc, Btdc, Cd273, Pdl2
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 2 precursor (Programmed death ligand 2) (PD-L2) (PD-1-ligand 2) (PDCD1 ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD273 antigen).

PPAC3_MOUSE
θ value	0.813845 (rank : 1341)	NC score	0.005798 (rank : 1874)
Query Neighborhood Hits	1959	Target Neighborhood Hits	22	Shared Neighborhood Hits	6
SwissProt Accessions	Q91WB2	Gene names	Ppapdc3
Domain Architecture	No domain graphic available
Description	Probable lipid phosphate phosphatase PPAPDC3 (EC 3.1.3.-) (Phosphatidic acid phosphatase type 2 domain-containing protein 3).

PRLR_HUMAN
θ value	0.813845 (rank : 1342)	NC score	0.017084 (rank : 1684)
Query Neighborhood Hits	1959	Target Neighborhood Hits	95	Shared Neighborhood Hits	33
SwissProt Accessions	P16471, Q16354, Q9BX87	Gene names	PRLR
Domain Architecture
Description	Prolactin receptor precursor (PRL-R).

PSG4_HUMAN
θ value	0.813845 (rank : 1343)	NC score	0.172521 (rank : 1032)
Query Neighborhood Hits	1959	Target Neighborhood Hits	243	Shared Neighborhood Hits	196
SwissProt Accessions	Q00888, Q13047, Q13048, Q15234, Q15240, Q9UQ76	Gene names	PSG4, CGM4, PSG9
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 4 precursor (PSBG-4) (PSBG-9).

PSG6_HUMAN
θ value	0.813845 (rank : 1344)	NC score	0.159895 (rank : 1043)
Query Neighborhood Hits	1959	Target Neighborhood Hits	231	Shared Neighborhood Hits	189
SwissProt Accessions	Q00889	Gene names	PSG6, CGM3, PSGGB
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 6 precursor (PSBG-6).

RBBP6_HUMAN
θ value	0.813845 (rank : 1345)	NC score	0.030748 (rank : 1506)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1135	Shared Neighborhood Hits	239
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RBBP6_MOUSE
θ value	0.813845 (rank : 1346)	NC score	0.042014 (rank : 1424)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1014	Shared Neighborhood Hits	226
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

S12A5_HUMAN
θ value	0.813845 (rank : 1347)	NC score	0.001393 (rank : 1946)
Query Neighborhood Hits	1959	Target Neighborhood Hits	68	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H2X9, Q5VZ41, Q9H4Z0, Q9ULP4	Gene names	SLC12A5, KCC2, KIAA1176
Domain Architecture
Description	Solute carrier family 12 member 5 (Electroneutral potassium-chloride cotransporter 2) (Erythroid K-Cl cotransporter 2) (Neuronal K-Cl cotransporter) (hKCC2).

SC6A5_HUMAN
θ value	0.813845 (rank : 1348)	NC score	-0.003556 (rank : 2021)
Query Neighborhood Hits	1959	Target Neighborhood Hits	69	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y345, O95288, Q9BX77	Gene names	SLC6A5, GLYT2
Domain Architecture
Description	Sodium- and chloride-dependent glycine transporter 2 (GlyT2) (GlyT-2) (Solute carrier family 6 member 5).

SF3B1_HUMAN
θ value	0.813845 (rank : 1349)	NC score	0.040043 (rank : 1440)
Query Neighborhood Hits	1959	Target Neighborhood Hits	341	Shared Neighborhood Hits	148
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_MOUSE
θ value	0.813845 (rank : 1350)	NC score	0.040987 (rank : 1436)
Query Neighborhood Hits	1959	Target Neighborhood Hits	352	Shared Neighborhood Hits	152
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SIG12_MOUSE
θ value	0.813845 (rank : 1351)	NC score	0.127357 (rank : 1078)
Query Neighborhood Hits	1959	Target Neighborhood Hits	225	Shared Neighborhood Hits	163
SwissProt Accessions	Q91Y57	Gene names	Siglec12, Siglec5, Siglece, Siglecl1
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 12 precursor (Siglec-12) (Sialic acid-binding Ig-like lectin-like 1) (Siglec-L1) (Sialic acid-binding Ig-like lectin 5) (Siglec-5) (mSiglec-E) (Myeloid inhibitory siglec) (MIS).

TAU_HUMAN
θ value	0.813845 (rank : 1352)	NC score	0.048124 (rank : 1379)
Query Neighborhood Hits	1959	Target Neighborhood Hits	448	Shared Neighborhood Hits	198
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TXLNA_HUMAN
θ value	0.813845 (rank : 1353)	NC score	0.029430 (rank : 1514)
Query Neighborhood Hits	1959	Target Neighborhood Hits	982	Shared Neighborhood Hits	175
SwissProt Accessions	P40222, Q66K62, Q86T54, Q86T85, Q86T86, Q86Y86, Q86YW3, Q8N2Y3	Gene names	TXLNA, TXLN
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

ZN318_HUMAN
θ value	0.813845 (rank : 1354)	NC score	0.029482 (rank : 1513)
Query Neighborhood Hits	1959	Target Neighborhood Hits	497	Shared Neighborhood Hits	115
SwissProt Accessions	Q5VUA4, O94796, Q4G0E4, Q8NEM6, Q9UNU8, Q9Y2W9	Gene names	ZNF318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Endocrine regulatory protein).

ACV1C_HUMAN
θ value	1.06291 (rank : 1355)	NC score	0.536291 (rank : 811)
Query Neighborhood Hits	1959	Target Neighborhood Hits	709	Shared Neighborhood Hits	684
SwissProt Accessions	Q8NER5, Q4ZFZ8, Q86UL1, Q86UL2, Q8TBG2	Gene names	ACVR1C, ALK7
Domain Architecture	No domain graphic available
Description	Activin receptor type 1C precursor (EC 2.7.11.30) (ACTR-IC) (Activin receptor-like kinase 7) (ALK-7).

ANK3_HUMAN
θ value	1.06291 (rank : 1356)	NC score	0.014053 (rank : 1728)
Query Neighborhood Hits	1959	Target Neighborhood Hits	853	Shared Neighborhood Hits	174
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

APXL_HUMAN
θ value	1.06291 (rank : 1357)	NC score	0.044220 (rank : 1405)
Query Neighborhood Hits	1959	Target Neighborhood Hits	553	Shared Neighborhood Hits	179
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

B3A3_HUMAN
θ value	1.06291 (rank : 1358)	NC score	0.002588 (rank : 1924)
Query Neighborhood Hits	1959	Target Neighborhood Hits	119	Shared Neighborhood Hits	43
SwissProt Accessions	P48751	Gene names	SLC4A3, AE3
Domain Architecture
Description	Anion exchange protein 3 (Neuronal band 3-like protein) (Solute carrier family 4 member 3) (Cardiac/brain band 3-like protein) (CAE3/BAE3).

BAG3_HUMAN
θ value	1.06291 (rank : 1359)	NC score	0.041404 (rank : 1428)
Query Neighborhood Hits	1959	Target Neighborhood Hits	314	Shared Neighborhood Hits	159
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

BAZ2A_HUMAN
θ value	1.06291 (rank : 1360)	NC score	0.031107 (rank : 1504)
Query Neighborhood Hits	1959	Target Neighborhood Hits	780	Shared Neighborhood Hits	260
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

BAZ2A_MOUSE
θ value	1.06291 (rank : 1361)	NC score	0.034053 (rank : 1481)
Query Neighborhood Hits	1959	Target Neighborhood Hits	744	Shared Neighborhood Hits	267
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

BCL9_HUMAN
θ value	1.06291 (rank : 1362)	NC score	0.056173 (rank : 1311)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1008	Shared Neighborhood Hits	374
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

BTBDC_HUMAN
θ value	1.06291 (rank : 1363)	NC score	0.034585 (rank : 1477)
Query Neighborhood Hits	1959	Target Neighborhood Hits	248	Shared Neighborhood Hits	96
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

CCNK_MOUSE
θ value	1.06291 (rank : 1364)	NC score	0.041144 (rank : 1433)
Query Neighborhood Hits	1959	Target Neighborhood Hits	350	Shared Neighborhood Hits	155
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

CEAM1_MOUSE
θ value	1.06291 (rank : 1365)	NC score	0.258273 (rank : 987)
Query Neighborhood Hits	1959	Target Neighborhood Hits	326	Shared Neighborhood Hits	245
SwissProt Accessions	P31809	Gene names	Ceacam1, Bgp, Bgp1, Bgpd
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 1 precursor (Biliary glycoprotein 1) (BGP-1) (Murine hepatitis virus receptor) (MHV-R) (Biliary glycoprotein D).

CENG1_MOUSE
θ value	1.06291 (rank : 1366)	NC score	0.003214 (rank : 1913)
Query Neighborhood Hits	1959	Target Neighborhood Hits	531	Shared Neighborhood Hits	104
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

CTGE6_HUMAN
θ value	1.06291 (rank : 1367)	NC score	0.007455 (rank : 1834)
Query Neighborhood Hits	1959	Target Neighborhood Hits	650	Shared Neighborhood Hits	75
SwissProt Accessions	Q86UF2	Gene names	CTAGE6
Domain Architecture	No domain graphic available
Description	Protein cTAGE-6 (cTAGE family member 6).

DBPA_HUMAN
θ value	1.06291 (rank : 1368)	NC score	0.011289 (rank : 1771)
Query Neighborhood Hits	1959	Target Neighborhood Hits	52	Shared Neighborhood Hits	20
SwissProt Accessions	P16989, Q14121, Q969N6	Gene names	CSDA, DBPA
Domain Architecture
Description	DNA-binding protein A (Cold shock domain-containing protein A) (Single-strand DNA-binding protein NF-GMB).

DIAP1_HUMAN
θ value	1.06291 (rank : 1369)	NC score	0.020966 (rank : 1628)
Query Neighborhood Hits	1959	Target Neighborhood Hits	784	Shared Neighborhood Hits	181
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

DSPP_MOUSE
θ value	1.06291 (rank : 1370)	NC score	0.022856 (rank : 1599)
Query Neighborhood Hits	1959	Target Neighborhood Hits	491	Shared Neighborhood Hits	101
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

EI2BD_HUMAN
θ value	1.06291 (rank : 1371)	NC score	0.012097 (rank : 1758)
Query Neighborhood Hits	1959	Target Neighborhood Hits	34	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UI10, Q5BJF4, Q9BUV9, Q9UBG4, Q9UIQ9, Q9UJ95	Gene names	EIF2B4, EIF2BD
Domain Architecture
Description	Translation initiation factor eIF-2B subunit delta (eIF-2B GDP-GTP exchange factor subunit delta).

FA47A_HUMAN
θ value	1.06291 (rank : 1372)	NC score	0.066091 (rank : 1245)
Query Neighborhood Hits	1959	Target Neighborhood Hits	451	Shared Neighborhood Hits	219
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

FMN2_HUMAN
θ value	1.06291 (rank : 1373)	NC score	0.038724 (rank : 1452)
Query Neighborhood Hits	1959	Target Neighborhood Hits	484	Shared Neighborhood Hits	182
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

FOG1_MOUSE
θ value	1.06291 (rank : 1374)	NC score	-0.004108 (rank : 2029)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1237	Shared Neighborhood Hits	308
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

GA2L1_HUMAN
θ value	1.06291 (rank : 1375)	NC score	0.020968 (rank : 1627)
Query Neighborhood Hits	1959	Target Neighborhood Hits	177	Shared Neighborhood Hits	67
SwissProt Accessions	Q99501, Q53EN7, Q92640, Q9BUY9	Gene names	GAS2L1, GAR22
Domain Architecture
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1) (GAS2-related protein on chromosome 22) (GAR22 protein).

GAK11_HUMAN
θ value	1.06291 (rank : 1376)	NC score	0.021655 (rank : 1615)
Query Neighborhood Hits	1959	Target Neighborhood Hits	409	Shared Neighborhood Hits	191
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK2_HUMAN
θ value	1.06291 (rank : 1377)	NC score	0.021136 (rank : 1622)
Query Neighborhood Hits	1959	Target Neighborhood Hits	406	Shared Neighborhood Hits	186
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GLIS1_MOUSE
θ value	1.06291 (rank : 1378)	NC score	-0.024486 (rank : 2101)
Query Neighborhood Hits	1959	Target Neighborhood Hits	751	Shared Neighborhood Hits	74
SwissProt Accessions	Q8K1M4, Q6NZF6, Q8R4Z3	Gene names	Glis1, Gli5
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS1 (GLI-similar 1) (Gli homologous protein 1) (GliH1).

GLIS3_MOUSE
θ value	1.06291 (rank : 1379)	NC score	-0.020485 (rank : 2094)
Query Neighborhood Hits	1959	Target Neighborhood Hits	861	Shared Neighborhood Hits	134
SwissProt Accessions	Q6XP49, Q8BI60	Gene names	Glis3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS3 (GLI-similar 3).

IL1R1_HUMAN
θ value	1.06291 (rank : 1380)	NC score	0.134474 (rank : 1073)
Query Neighborhood Hits	1959	Target Neighborhood Hits	140	Shared Neighborhood Hits	119
SwissProt Accessions	P14778	Gene names	IL1R1, IL1R, IL1RA, IL1RT1
Domain Architecture
Description	Interleukin-1 receptor type I precursor (IL-1R-1) (IL-1RT1) (IL-1R- alpha) (p80) (CD121a antigen).

IRAK1_HUMAN
θ value	1.06291 (rank : 1381)	NC score	0.679838 (rank : 657)
Query Neighborhood Hits	1959	Target Neighborhood Hits	820	Shared Neighborhood Hits	767
SwissProt Accessions	P51617, Q7Z5V4, Q96RL2	Gene names	IRAK1, IRAK
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1).

IRAK3_HUMAN
θ value	1.06291 (rank : 1382)	NC score	0.583713 (rank : 794)
Query Neighborhood Hits	1959	Target Neighborhood Hits	644	Shared Neighborhood Hits	620
SwissProt Accessions	Q9Y616	Gene names	IRAK3
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1) (IRAK-3) (IL- 1 receptor-associated kinase M) (IRAK-M).

IRS1_MOUSE
θ value	1.06291 (rank : 1383)	NC score	0.017557 (rank : 1674)
Query Neighborhood Hits	1959	Target Neighborhood Hits	112	Shared Neighborhood Hits	48
SwissProt Accessions	P35569	Gene names	Irs1, Irs-1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

JAM1_HUMAN
θ value	1.06291 (rank : 1384)	NC score	0.288019 (rank : 958)
Query Neighborhood Hits	1959	Target Neighborhood Hits	294	Shared Neighborhood Hits	234
SwissProt Accessions	Q9Y624	Gene names	F11R, JAM1, JCAM
Domain Architecture
Description	Junctional adhesion molecule A precursor (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (Platelet adhesion molecule 1) (PAM-1) (Platelet F11 receptor) (CD321 antigen).

JIP2_MOUSE
θ value	1.06291 (rank : 1385)	NC score	0.019133 (rank : 1650)
Query Neighborhood Hits	1959	Target Neighborhood Hits	144	Shared Neighborhood Hits	40
SwissProt Accessions	Q9ERE9, Q9CXI4	Gene names	Mapk8ip2, Ib2, Jip2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

K0460_MOUSE
θ value	1.06291 (rank : 1386)	NC score	0.027510 (rank : 1530)
Query Neighborhood Hits	1959	Target Neighborhood Hits	374	Shared Neighborhood Hits	114
SwissProt Accessions	Q6NXI6, Q3U3L8, Q6ZQA7	Gene names	Kiaa0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

K2C7_HUMAN
θ value	1.06291 (rank : 1387)	NC score	-0.005849 (rank : 2045)
Query Neighborhood Hits	1959	Target Neighborhood Hits	369	Shared Neighborhood Hits	24
SwissProt Accessions	P08729, Q92676, Q9BUD8, Q9Y3R7	Gene names	KRT7, SCL
Domain Architecture
Description	Keratin, type II cytoskeletal 7 (Cytokeratin-7) (CK-7) (Keratin-7) (K7) (Sarcolectin).

LRRF1_HUMAN
θ value	1.06291 (rank : 1388)	NC score	0.015788 (rank : 1704)
Query Neighborhood Hits	1959	Target Neighborhood Hits	625	Shared Neighborhood Hits	88
SwissProt Accessions	Q32MZ4, O75766, O75799, Q32MZ5, Q53T49, Q6PKG2	Gene names	LRRFIP1, GCF2, TRIP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (TAR RNA-interacting protein) (GC-binding factor 2).

MALT1_HUMAN
θ value	1.06291 (rank : 1389)	NC score	0.305434 (rank : 942)
Query Neighborhood Hits	1959	Target Neighborhood Hits	236	Shared Neighborhood Hits	208
SwissProt Accessions	Q9UDY8, Q9NTB7, Q9ULX4	Gene names	MALT1, MLT
Domain Architecture
Description	Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (EC 3.4.22.-) (MALT lymphoma-associated translocation) (Paracaspase).

MILK1_HUMAN
θ value	1.06291 (rank : 1390)	NC score	0.033822 (rank : 1482)
Query Neighborhood Hits	1959	Target Neighborhood Hits	427	Shared Neighborhood Hits	181
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MKL1_HUMAN
θ value	1.06291 (rank : 1391)	NC score	0.022089 (rank : 1609)
Query Neighborhood Hits	1959	Target Neighborhood Hits	232	Shared Neighborhood Hits	90
SwissProt Accessions	Q969V6, Q8TCL1, Q96SC5, Q96SC6, Q9P2B0	Gene names	MKL1, KIAA1438, MAL
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein) (Megakaryocytic acute leukemia protein).

MKL2_MOUSE
θ value	1.06291 (rank : 1392)	NC score	0.016166 (rank : 1697)
Query Neighborhood Hits	1959	Target Neighborhood Hits	269	Shared Neighborhood Hits	77
SwissProt Accessions	P59759	Gene names	Mkl2, Mrtfb
Domain Architecture
Description	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B).

MYO15_MOUSE
θ value	1.06291 (rank : 1393)	NC score	0.022635 (rank : 1603)
Query Neighborhood Hits	1959	Target Neighborhood Hits	467	Shared Neighborhood Hits	188
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

NFIC_MOUSE
θ value	1.06291 (rank : 1394)	NC score	0.004823 (rank : 1886)
Query Neighborhood Hits	1959	Target Neighborhood Hits	66	Shared Neighborhood Hits	26
SwissProt Accessions	P70255, O09072, P70256, Q3U2I9, Q99MA3, Q99MA4, Q99MA5, Q99MA6, Q99MA7, Q99MA8, Q9R1G3	Gene names	Nfic
Domain Architecture
Description	Nuclear factor 1 C-type (Nuclear factor 1/C) (NF1-C) (NFI-C) (NF-I/C) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

NFM_HUMAN
θ value	1.06291 (rank : 1395)	NC score	0.014580 (rank : 1721)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1328	Shared Neighborhood Hits	241
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

PCX3_MOUSE
θ value	1.06291 (rank : 1396)	NC score	0.020676 (rank : 1635)
Query Neighborhood Hits	1959	Target Neighborhood Hits	134	Shared Neighborhood Hits	63
SwissProt Accessions	Q8VI59	Gene names	Pcnxl3
Domain Architecture
Description	Pecanex-like protein 3.

PDC6I_MOUSE
θ value	1.06291 (rank : 1397)	NC score	0.025647 (rank : 1553)
Query Neighborhood Hits	1959	Target Neighborhood Hits	275	Shared Neighborhood Hits	105
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

PHC2_HUMAN
θ value	1.06291 (rank : 1398)	NC score	0.035974 (rank : 1469)
Query Neighborhood Hits	1959	Target Neighborhood Hits	388	Shared Neighborhood Hits	179
SwissProt Accessions	Q8IXK0, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7	Gene names	PHC2, EDR2, PH2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2).

PPRB_MOUSE
θ value	1.06291 (rank : 1399)	NC score	0.037554 (rank : 1458)
Query Neighborhood Hits	1959	Target Neighborhood Hits	354	Shared Neighborhood Hits	133
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

PRB3_HUMAN
θ value	1.06291 (rank : 1400)	NC score	0.064735 (rank : 1255)
Query Neighborhood Hits	1959	Target Neighborhood Hits	318	Shared Neighborhood Hits	160
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

PTCD1_HUMAN
θ value	1.06291 (rank : 1401)	NC score	0.010642 (rank : 1784)
Query Neighborhood Hits	1959	Target Neighborhood Hits	52	Shared Neighborhood Hits	24
SwissProt Accessions	O75127, Q66K60, Q9UDV2	Gene names	PTCD1, KIAA0632
Domain Architecture	No domain graphic available
Description	Pentatricopeptide repeat protein 1.

QSCN6_HUMAN
θ value	1.06291 (rank : 1402)	NC score	0.006319 (rank : 1861)
Query Neighborhood Hits	1959	Target Neighborhood Hits	98	Shared Neighborhood Hits	30
SwissProt Accessions	O00391, Q59G29, Q5T2X0, Q8TDL6, Q8WVP4	Gene names	QSCN6, QSOX1
Domain Architecture	No domain graphic available
Description	Sulfhydryl oxidase 1 precursor (EC 1.8.3.2) (Quiescin Q6) (hQSOX).

RANB3_MOUSE
θ value	1.06291 (rank : 1403)	NC score	0.016990 (rank : 1688)
Query Neighborhood Hits	1959	Target Neighborhood Hits	123	Shared Neighborhood Hits	57
SwissProt Accessions	Q9CT10, Q3TIS4, Q3U2G4, Q3UYG7	Gene names	Ranbp3
Domain Architecture	No domain graphic available
Description	Ran-binding protein 3 (RanBP3).

S12A5_MOUSE
θ value	1.06291 (rank : 1404)	NC score	0.000808 (rank : 1958)
Query Neighborhood Hits	1959	Target Neighborhood Hits	59	Shared Neighborhood Hits	5
SwissProt Accessions	Q91V14, Q9Z0M7	Gene names	Slc12a5, Kcc2
Domain Architecture
Description	Solute carrier family 12 member 5 (Electroneutral potassium-chloride cotransporter 2) (K-Cl cotransporter 2) (Neuronal K-Cl cotransporter) (mKCC2).

SAM68_HUMAN
θ value	1.06291 (rank : 1405)	NC score	0.009830 (rank : 1797)
Query Neighborhood Hits	1959	Target Neighborhood Hits	68	Shared Neighborhood Hits	27
SwissProt Accessions	Q07666, Q6PJX7, Q8NB97, Q99760	Gene names	KHDRBS1, SAM68
Domain Architecture	No domain graphic available
Description	KH domain-containing, RNA-binding, signal transduction-associated protein 1 (p21 Ras GTPase-activating protein-associated p62) (GAP- associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p68).

SF01_HUMAN
θ value	1.06291 (rank : 1406)	NC score	0.043942 (rank : 1408)
Query Neighborhood Hits	1959	Target Neighborhood Hits	287	Shared Neighborhood Hits	133
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

SFRS2_HUMAN
θ value	1.06291 (rank : 1407)	NC score	-0.003261 (rank : 2017)
Query Neighborhood Hits	1959	Target Neighborhood Hits	222	Shared Neighborhood Hits	31
SwissProt Accessions	Q01130	Gene names	SFRS2
Domain Architecture
Description	Splicing factor, arginine/serine-rich 2 (Splicing factor SC35) (SC-35) (Splicing component, 35 kDa) (Protein PR264).

SFRS2_MOUSE
θ value	1.06291 (rank : 1408)	NC score	-0.003261 (rank : 2018)
Query Neighborhood Hits	1959	Target Neighborhood Hits	222	Shared Neighborhood Hits	31
SwissProt Accessions	Q62093, Q542L3, Q60701	Gene names	Sfrs2, Pr264, Sfrs10
Domain Architecture
Description	Splicing factor, arginine/serine-rich 2 (Splicing factor SC35) (SC-35) (Splicing component, 35 kDa) (Protein PR264) (Putative myelin regulatory factor 1) (MRF-1).

SGIP1_HUMAN
θ value	1.06291 (rank : 1409)	NC score	0.031731 (rank : 1501)
Query Neighborhood Hits	1959	Target Neighborhood Hits	198	Shared Neighborhood Hits	98
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SIN3A_MOUSE
θ value	1.06291 (rank : 1410)	NC score	0.014136 (rank : 1726)
Query Neighborhood Hits	1959	Target Neighborhood Hits	169	Shared Neighborhood Hits	71
SwissProt Accessions	Q60520, Q60820, Q62139, Q62140, Q7TPU8, Q7TSZ2	Gene names	Sin3a
Domain Architecture
Description	Paired amphipathic helix protein Sin3a (Transcriptional corepressor Sin3a) (Histone deacetylase complex subunit Sin3a).

STK31_HUMAN
θ value	1.06291 (rank : 1411)	NC score	0.342625 (rank : 915)
Query Neighborhood Hits	1959	Target Neighborhood Hits	570	Shared Neighborhood Hits	374
SwissProt Accessions	Q9BXU1, Q9BXH8	Gene names	STK31
Domain Architecture
Description	Serine/threonine-protein kinase 31 (EC 2.7.11.1) (Serine/threonine- protein kinase NYD-SPK).

TCOF_HUMAN
θ value	1.06291 (rank : 1412)	NC score	0.051887 (rank : 1341)
Query Neighborhood Hits	1959	Target Neighborhood Hits	543	Shared Neighborhood Hits	190
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

TRPM6_HUMAN
θ value	1.06291 (rank : 1413)	NC score	-0.000898 (rank : 1988)
Query Neighborhood Hits	1959	Target Neighborhood Hits	91	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BX84, Q6VPR8, Q6VPR9, Q6VPS0, Q6VPS1, Q6VPS2	Gene names	TRPM6, CHAK2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6).

UNC5C_MOUSE
θ value	1.06291 (rank : 1414)	NC score	0.121586 (rank : 1094)
Query Neighborhood Hits	1959	Target Neighborhood Hits	225	Shared Neighborhood Hits	143
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

USBP1_HUMAN
θ value	1.06291 (rank : 1415)	NC score	0.006045 (rank : 1869)
Query Neighborhood Hits	1959	Target Neighborhood Hits	188	Shared Neighborhood Hits	32
SwissProt Accessions	Q8N6Y0, Q8NBX7, Q96KH3, Q9BYI8	Gene names	USHBP1, AIEBP, MCC2
Domain Architecture	No domain graphic available
Description	USH1C-binding protein 1 (Usher syndrome type-1C protein-binding protein 1) (MCC-2) (AIE-75 binding protein).

WAPL_HUMAN
θ value	1.06291 (rank : 1416)	NC score	0.012732 (rank : 1747)
Query Neighborhood Hits	1959	Target Neighborhood Hits	122	Shared Neighborhood Hits	26
SwissProt Accessions	Q7Z5K2, Q5VSK5, Q8IX10, Q92549	Gene names	WAPAL, FOE, KIAA0261, WAPL
Domain Architecture	No domain graphic available
Description	Wings apart-like protein homolog (Friend of EBNA2 protein).

ZEP2_HUMAN
θ value	1.06291 (rank : 1417)	NC score	-0.013454 (rank : 2078)
Query Neighborhood Hits	1959	Target Neighborhood Hits	937	Shared Neighborhood Hits	139
SwissProt Accessions	P31629, Q02646, Q5THT5, Q9NS05	Gene names	HIVEP2
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 (HIV- EP2) (MHC-binding protein 2) (MBP-2).

ZEP2_MOUSE
θ value	1.06291 (rank : 1418)	NC score	-0.012287 (rank : 2074)
Query Neighborhood Hits	1959	Target Neighborhood Hits	964	Shared Neighborhood Hits	160
SwissProt Accessions	Q3UHF7, O55140, Q3UVD4, Q3UVH5	Gene names	Hivep2, Mibp1
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 homolog (Myc intron-binding protein 1) (MIBP-1).

ZN318_MOUSE
θ value	1.06291 (rank : 1419)	NC score	0.023603 (rank : 1583)
Query Neighborhood Hits	1959	Target Neighborhood Hits	642	Shared Neighborhood Hits	135
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

ACVL1_MOUSE
θ value	1.38821 (rank : 1420)	NC score	0.574788 (rank : 800)
Query Neighborhood Hits	1959	Target Neighborhood Hits	739	Shared Neighborhood Hits	724
SwissProt Accessions	Q61288, Q61289	Gene names	Acvrl1, Acvrlk1, Alk-1
Domain Architecture
Description	Serine/threonine-protein kinase receptor R3 precursor (EC 2.7.11.30) (SKR3) (Activin receptor-like kinase 1) (ALK-1) (TGF-B superfamily receptor type I) (TSR-I).

ADAM9_MOUSE
θ value	1.38821 (rank : 1421)	NC score	-0.006813 (rank : 2052)
Query Neighborhood Hits	1959	Target Neighborhood Hits	325	Shared Neighborhood Hits	42
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

AF17_HUMAN
θ value	1.38821 (rank : 1422)	NC score	0.015928 (rank : 1703)
Query Neighborhood Hits	1959	Target Neighborhood Hits	230	Shared Neighborhood Hits	84
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

AMGO3_MOUSE
θ value	1.38821 (rank : 1423)	NC score	0.044936 (rank : 1398)
Query Neighborhood Hits	1959	Target Neighborhood Hits	276	Shared Neighborhood Hits	80
SwissProt Accessions	Q8C2S7, Q6ZPH1, Q8CEB3	Gene names	Amigo3, Ali3, Kiaa1851
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 3 precursor (AMIGO-3) (Alivin-3).

ATS14_HUMAN
θ value	1.38821 (rank : 1424)	NC score	0.007373 (rank : 1835)
Query Neighborhood Hits	1959	Target Neighborhood Hits	382	Shared Neighborhood Hits	129
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

B4GN4_HUMAN
θ value	1.38821 (rank : 1425)	NC score	0.011277 (rank : 1772)
Query Neighborhood Hits	1959	Target Neighborhood Hits	131	Shared Neighborhood Hits	55
SwissProt Accessions	Q76KP1, Q96LV2	Gene names	B4GALNT4
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 1 (EC 2.4.1.244) (NGalNAc-T1) (Beta- 1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4).

CHD4_MOUSE
θ value	1.38821 (rank : 1426)	NC score	0.002841 (rank : 1921)
Query Neighborhood Hits	1959	Target Neighborhood Hits	408	Shared Neighborhood Hits	100
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

CNTRB_HUMAN
θ value	1.38821 (rank : 1427)	NC score	0.025644 (rank : 1554)
Query Neighborhood Hits	1959	Target Neighborhood Hits	690	Shared Neighborhood Hits	97
SwissProt Accessions	Q8N137, Q331K3, Q69YV7, Q8NCB8, Q8WXV3, Q96CQ7, Q9C060	Gene names	CNTROB, LIP8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

DDX54_MOUSE
θ value	1.38821 (rank : 1428)	NC score	-0.005812 (rank : 2044)
Query Neighborhood Hits	1959	Target Neighborhood Hits	124	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K4L0	Gene names	Ddx54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54).

ENAH_MOUSE
θ value	1.38821 (rank : 1429)	NC score	0.058671 (rank : 1292)
Query Neighborhood Hits	1959	Target Neighborhood Hits	919	Shared Neighborhood Hits	286
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

FA47B_HUMAN
θ value	1.38821 (rank : 1430)	NC score	0.066084 (rank : 1246)
Query Neighborhood Hits	1959	Target Neighborhood Hits	431	Shared Neighborhood Hits	210
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

FA61A_MOUSE
θ value	1.38821 (rank : 1431)	NC score	0.023505 (rank : 1585)
Query Neighborhood Hits	1959	Target Neighborhood Hits	81	Shared Neighborhood Hits	46
SwissProt Accessions	Q8K2F8, Q9CTG8	Gene names	Fam61a
Domain Architecture	No domain graphic available
Description	Protein FAM61A.

FOXL2_HUMAN
θ value	1.38821 (rank : 1432)	NC score	-0.000670 (rank : 1984)
Query Neighborhood Hits	1959	Target Neighborhood Hits	142	Shared Neighborhood Hits	43
SwissProt Accessions	P58012, Q4ZGJ3	Gene names	FOXL2
Domain Architecture
Description	Forkhead box protein L2.

GLU2B_MOUSE
θ value	1.38821 (rank : 1433)	NC score	0.016943 (rank : 1689)
Query Neighborhood Hits	1959	Target Neighborhood Hits	357	Shared Neighborhood Hits	59
SwissProt Accessions	O08795, Q921X2	Gene names	Prkcsh
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

GP162_HUMAN
θ value	1.38821 (rank : 1434)	NC score	-0.004693 (rank : 2036)
Query Neighborhood Hits	1959	Target Neighborhood Hits	244	Shared Neighborhood Hits	4
SwissProt Accessions	Q16538, Q16664, Q59EH5, Q66K56	Gene names	GPR162, GRCA
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 162 (Gene-rich cluster gene A protein).

HB2A_MOUSE
θ value	1.38821 (rank : 1435)	NC score	-0.011000 (rank : 2070)
Query Neighborhood Hits	1959	Target Neighborhood Hits	203	Shared Neighborhood Hits	10
SwissProt Accessions	P14483	Gene names	H2-Ab1, H2-iabeta
Domain Architecture
Description	H-2 class II histocompatibility antigen, A beta chain precursor.

HCFC2_MOUSE
θ value	1.38821 (rank : 1436)	NC score	0.115596 (rank : 1104)
Query Neighborhood Hits	1959	Target Neighborhood Hits	97	Shared Neighborhood Hits	88
SwissProt Accessions	Q9D968	Gene names	Hcfc2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

HDAC7_MOUSE
θ value	1.38821 (rank : 1437)	NC score	0.004361 (rank : 1892)
Query Neighborhood Hits	1959	Target Neighborhood Hits	85	Shared Neighborhood Hits	22
SwissProt Accessions	Q8C2B3, Q8C2C9, Q8C8X4, Q8CB80, Q8CDA3, Q9JL72	Gene names	Hdac7a, Hdac7
Domain Architecture
Description	Histone deacetylase 7a (HD7a).

HIC1_HUMAN
θ value	1.38821 (rank : 1438)	NC score	-0.026842 (rank : 2112)
Query Neighborhood Hits	1959	Target Neighborhood Hits	838	Shared Neighborhood Hits	77
SwissProt Accessions	Q14526	Gene names	HIC1, ZBTB29
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1) (Zinc finger and BTB domain-containing protein 29).

HXB3_MOUSE
θ value	1.38821 (rank : 1439)	NC score	-0.010936 (rank : 2069)
Query Neighborhood Hits	1959	Target Neighborhood Hits	493	Shared Neighborhood Hits	82
SwissProt Accessions	P09026, P10285, Q4PJ06, Q61680	Gene names	Hoxb3, Hox-2.7, Hoxb-3
Domain Architecture
Description	Homeobox protein Hox-B3 (Hox-2.7) (Homeobox protein MH-23).

IF39_MOUSE
θ value	1.38821 (rank : 1440)	NC score	0.024496 (rank : 1567)
Query Neighborhood Hits	1959	Target Neighborhood Hits	206	Shared Neighborhood Hits	74
SwissProt Accessions	Q8JZQ9, Q922K2	Gene names	Eif3s9
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116).

K1210_HUMAN
θ value	1.38821 (rank : 1441)	NC score	0.021953 (rank : 1611)
Query Neighborhood Hits	1959	Target Neighborhood Hits	219	Shared Neighborhood Hits	79
SwissProt Accessions	Q9ULL0, Q5JPN4	Gene names	KIAA1210
Domain Architecture	No domain graphic available
Description	Protein KIAA1210.

KCNC3_HUMAN
θ value	1.38821 (rank : 1442)	NC score	0.000961 (rank : 1957)
Query Neighborhood Hits	1959	Target Neighborhood Hits	256	Shared Neighborhood Hits	83
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNC3_MOUSE
θ value	1.38821 (rank : 1443)	NC score	-0.003242 (rank : 2016)
Query Neighborhood Hits	1959	Target Neighborhood Hits	173	Shared Neighborhood Hits	36
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

MARCS_HUMAN
θ value	1.38821 (rank : 1444)	NC score	0.053880 (rank : 1323)
Query Neighborhood Hits	1959	Target Neighborhood Hits	204	Shared Neighborhood Hits	99
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

MEGF9_HUMAN
θ value	1.38821 (rank : 1445)	NC score	0.022947 (rank : 1598)
Query Neighborhood Hits	1959	Target Neighborhood Hits	557	Shared Neighborhood Hits	150
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MKL1_MOUSE
θ value	1.38821 (rank : 1446)	NC score	0.043182 (rank : 1413)
Query Neighborhood Hits	1959	Target Neighborhood Hits	667	Shared Neighborhood Hits	272
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

MLL3_MOUSE
θ value	1.38821 (rank : 1447)	NC score	0.051238 (rank : 1345)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1399	Shared Neighborhood Hits	382
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MYCB2_HUMAN
θ value	1.38821 (rank : 1448)	NC score	0.025788 (rank : 1551)
Query Neighborhood Hits	1959	Target Neighborhood Hits	390	Shared Neighborhood Hits	104
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

NOTC2_MOUSE
θ value	1.38821 (rank : 1449)	NC score	0.003249 (rank : 1912)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1069	Shared Neighborhood Hits	182
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NPBL_MOUSE
θ value	1.38821 (rank : 1450)	NC score	0.044924 (rank : 1399)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1041	Shared Neighborhood Hits	283
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

P73L_HUMAN
θ value	1.38821 (rank : 1451)	NC score	0.008376 (rank : 1816)
Query Neighborhood Hits	1959	Target Neighborhood Hits	102	Shared Neighborhood Hits	43
SwissProt Accessions	Q9H3D4, O75080, O75195, O75922, O76078, Q6VEG2, Q6VEG3, Q6VEG4, Q6VFJ1, Q6VFJ2, Q6VFJ3, Q6VH20, Q7LDI3, Q7LDI4, Q7LDI5, Q96KR0, Q9H3D2, Q9H3D3, Q9H3P8, Q9NPH7, Q9P1B4, Q9P1B5, Q9P1B6, Q9P1B7, Q9UBV9, Q9UE10, Q9UP26, Q9UP27, Q9UP28, Q9UP74	Gene names	TP73L, KET, P63, P73H, P73L
Domain Architecture	No domain graphic available
Description	Tumor protein p73-like (p73L) (p63) (Tumor protein 63) (TP63) (p51) (p40) (Keratinocyte transcription factor KET) (Chronic ulcerative stomatitis protein) (CUSP).

PDC6I_HUMAN
θ value	1.38821 (rank : 1452)	NC score	0.033289 (rank : 1489)
Query Neighborhood Hits	1959	Target Neighborhood Hits	278	Shared Neighborhood Hits	124
SwissProt Accessions	Q8WUM4, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5	Gene names	PDCD6IP, AIP1, ALIX, KIAA1375
Domain Architecture
Description	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95).

PO121_HUMAN
θ value	1.38821 (rank : 1453)	NC score	0.048366 (rank : 1377)
Query Neighborhood Hits	1959	Target Neighborhood Hits	344	Shared Neighborhood Hits	144
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

PSG1_HUMAN
θ value	1.38821 (rank : 1454)	NC score	0.163584 (rank : 1039)
Query Neighborhood Hits	1959	Target Neighborhood Hits	232	Shared Neighborhood Hits	195
SwissProt Accessions	P11464, O75236, P11462, P11463, Q15231, Q15241, Q15243, Q16660, Q9P1W5, Q9UQ79	Gene names	PSG1, B1G1, PSGGA
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 1 precursor (PSBG-1) (Pregnancy-specific beta-1 glycoprotein C/D) (PS-beta-C/D) (Fetal liver non-specific cross-reactive antigen 1/2) (FL-NCA-1/2) (PSG95) (CD66f antigen).

PXK_MOUSE
θ value	1.38821 (rank : 1455)	NC score	0.172880 (rank : 1031)
Query Neighborhood Hits	1959	Target Neighborhood Hits	320	Shared Neighborhood Hits	226
SwissProt Accessions	Q8BX57, Q3TD60, Q3TEL7, Q3TZZ1, Q3U197, Q3U773, Q3UCS5, Q4FBH7, Q91WB6	Gene names	Pxk
Domain Architecture	No domain graphic available
Description	PX domain-containing protein kinase-like protein (Modulator of Na,K- ATPase) (MONaKA).

SCG1_HUMAN
θ value	1.38821 (rank : 1456)	NC score	0.010176 (rank : 1790)
Query Neighborhood Hits	1959	Target Neighborhood Hits	156	Shared Neighborhood Hits	37
SwissProt Accessions	P05060, Q9BQV6, Q9UJA6	Gene names	CHGB, SCG1
Domain Architecture
Description	Secretogranin-1 precursor (Secretogranin I) (SgI) (Chromogranin B) (CgB) [Contains: GAWK peptide; CCB peptide].

SOX17_HUMAN
θ value	1.38821 (rank : 1457)	NC score	-0.000501 (rank : 1982)
Query Neighborhood Hits	1959	Target Neighborhood Hits	108	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H6I2	Gene names	SOX17
Domain Architecture
Description	Transcription factor SOX-17.

SPTN4_HUMAN
θ value	1.38821 (rank : 1458)	NC score	0.003357 (rank : 1908)
Query Neighborhood Hits	1959	Target Neighborhood Hits	570	Shared Neighborhood Hits	88
SwissProt Accessions	Q9H254, Q9H1K7, Q9H1K8, Q9H1K9, Q9H3G8, Q9HCD0	Gene names	SPTBN4, KIAA1642, SPTBN3
Domain Architecture
Description	Spectrin beta chain, brain 3 (Spectrin, non-erythroid beta chain 3) (Beta-IV spectrin).

SYNJ1_MOUSE
θ value	1.38821 (rank : 1459)	NC score	0.049848 (rank : 1362)
Query Neighborhood Hits	1959	Target Neighborhood Hits	516	Shared Neighborhood Hits	256
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

TECT3_MOUSE
θ value	1.38821 (rank : 1460)	NC score	0.006175 (rank : 1864)
Query Neighborhood Hits	1959	Target Neighborhood Hits	33	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R2Q6, Q8CDF3, Q9CRC5	Gene names	Tect3
Domain Architecture	No domain graphic available
Description	Tectonic-3 precursor.

TXND2_HUMAN
θ value	1.38821 (rank : 1461)	NC score	0.070904 (rank : 1211)
Query Neighborhood Hits	1959	Target Neighborhood Hits	793	Shared Neighborhood Hits	275
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

WASF2_MOUSE
θ value	1.38821 (rank : 1462)	NC score	0.039361 (rank : 1447)
Query Neighborhood Hits	1959	Target Neighborhood Hits	315	Shared Neighborhood Hits	170
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

WBS14_MOUSE
θ value	1.38821 (rank : 1463)	NC score	0.028067 (rank : 1526)
Query Neighborhood Hits	1959	Target Neighborhood Hits	171	Shared Neighborhood Hits	75
SwissProt Accessions	Q99MZ3, Q99MY9, Q99MZ0, Q99MZ1, Q99MZ2, Q9JLM5	Gene names	Mlxipl, Mio, Wbscr14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein homolog (Mlx interactor) (MLX-interacting protein-like).

ZN219_HUMAN
θ value	1.38821 (rank : 1464)	NC score	-0.019401 (rank : 2093)
Query Neighborhood Hits	1959	Target Neighborhood Hits	876	Shared Neighborhood Hits	137
SwissProt Accessions	Q9P2Y4, Q8IYC1, Q9BW28	Gene names	ZNF219
Domain Architecture	No domain graphic available
Description	Zinc finger protein 219.

ZN447_HUMAN
θ value	1.38821 (rank : 1465)	NC score	-0.018733 (rank : 2091)
Query Neighborhood Hits	1959	Target Neighborhood Hits	899	Shared Neighborhood Hits	129
SwissProt Accessions	Q8TBC5, Q9BRK7, Q9H9A0	Gene names	ZNF447
Domain Architecture	No domain graphic available
Description	Zinc finger protein 447.

ARHG3_HUMAN
θ value	1.81305 (rank : 1466)	NC score	0.007571 (rank : 1832)
Query Neighborhood Hits	1959	Target Neighborhood Hits	82	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NR81, Q6NUN3, Q7Z4U2, Q7Z5T2, Q9H7T4	Gene names	ARHGEF3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3 (Exchange factor found in platelets and leukemic and neuronal tissues) (XPLN).

ARMX2_MOUSE
θ value	1.81305 (rank : 1467)	NC score	0.023840 (rank : 1575)
Query Neighborhood Hits	1959	Target Neighborhood Hits	349	Shared Neighborhood Hits	158
SwissProt Accessions	Q6A058, Q9CXI9	Gene names	Armcx2, Kiaa0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2.

BAG3_MOUSE
θ value	1.81305 (rank : 1468)	NC score	0.048690 (rank : 1374)
Query Neighborhood Hits	1959	Target Neighborhood Hits	513	Shared Neighborhood Hits	243
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

BASP_MOUSE
θ value	1.81305 (rank : 1469)	NC score	0.073021 (rank : 1202)
Query Neighborhood Hits	1959	Target Neighborhood Hits	260	Shared Neighborhood Hits	114
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BT1A1_MOUSE
θ value	1.81305 (rank : 1470)	NC score	0.039806 (rank : 1444)
Query Neighborhood Hits	1959	Target Neighborhood Hits	252	Shared Neighborhood Hits	105
SwissProt Accessions	Q62556, P97392, Q8K2H7, Q921K7	Gene names	Btn1a1, Btn
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

CABIN_HUMAN
θ value	1.81305 (rank : 1471)	NC score	0.049879 (rank : 1359)
Query Neighborhood Hits	1959	Target Neighborhood Hits	490	Shared Neighborhood Hits	232
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

CBP_MOUSE
θ value	1.81305 (rank : 1472)	NC score	0.057456 (rank : 1300)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1051	Shared Neighborhood Hits	403
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CEL_HUMAN
θ value	1.81305 (rank : 1473)	NC score	0.038749 (rank : 1451)
Query Neighborhood Hits	1959	Target Neighborhood Hits	896	Shared Neighborhood Hits	332
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

CLIC6_HUMAN
θ value	1.81305 (rank : 1474)	NC score	0.010354 (rank : 1785)
Query Neighborhood Hits	1959	Target Neighborhood Hits	289	Shared Neighborhood Hits	97
SwissProt Accessions	Q96NY7, Q8IX31	Gene names	CLIC6, CLIC1L
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel 6.

COGA1_HUMAN
θ value	1.81305 (rank : 1475)	NC score	0.008099 (rank : 1821)
Query Neighborhood Hits	1959	Target Neighborhood Hits	345	Shared Neighborhood Hits	112
SwissProt Accessions	Q07092	Gene names	COL16A1
Domain Architecture
Description	Collagen alpha-1(XVI) chain precursor.

CSKI1_MOUSE
θ value	1.81305 (rank : 1476)	NC score	0.050120 (rank : 1357)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1031	Shared Neighborhood Hits	376
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CUTL2_MOUSE
θ value	1.81305 (rank : 1477)	NC score	0.014911 (rank : 1718)
Query Neighborhood Hits	1959	Target Neighborhood Hits	771	Shared Neighborhood Hits	144
SwissProt Accessions	P70298	Gene names	Cutl2
Domain Architecture
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

DIP2A_HUMAN
θ value	1.81305 (rank : 1478)	NC score	0.007651 (rank : 1830)
Query Neighborhood Hits	1959	Target Neighborhood Hits	48	Shared Neighborhood Hits	18
SwissProt Accessions	Q14689, Q8IVA3, Q8N4S2, Q8TD89, Q96ML9	Gene names	DIP2A, C21orf106, DIP2, KIAA0184
Domain Architecture
Description	Disco-interacting protein 2 homolog A.

DPOD1_HUMAN
θ value	1.81305 (rank : 1479)	NC score	0.001934 (rank : 1934)
Query Neighborhood Hits	1959	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	P28340, Q8NER3, Q96H98	Gene names	POLD1, POLD
Domain Architecture
Description	DNA polymerase delta catalytic subunit (EC 2.7.7.7) (DNA polymerase subunit delta p125).

E2F4_HUMAN
θ value	1.81305 (rank : 1480)	NC score	0.011131 (rank : 1773)
Query Neighborhood Hits	1959	Target Neighborhood Hits	188	Shared Neighborhood Hits	75
SwissProt Accessions	Q16254, Q12991, Q15328	Gene names	E2F4
Domain Architecture
Description	Transcription factor E2F4 (E2F-4).

ES8L1_MOUSE
θ value	1.81305 (rank : 1481)	NC score	0.020673 (rank : 1636)
Query Neighborhood Hits	1959	Target Neighborhood Hits	143	Shared Neighborhood Hits	45
SwissProt Accessions	Q8R5F8, Q8R0D6, Q9D2M6	Gene names	Eps8l1, Eps8r1
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 1 (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-like protein 1).

FBSH_HUMAN
θ value	1.81305 (rank : 1482)	NC score	0.016487 (rank : 1696)
Query Neighborhood Hits	1959	Target Neighborhood Hits	46	Shared Neighborhood Hits	26
SwissProt Accessions	Q9HAH7, Q96CI9, Q9H9X4	Gene names	FBS1, FBS
Domain Architecture	No domain graphic available
Description	Probable fibrosin-1 long transcript protein.

FLIP1_HUMAN
θ value	1.81305 (rank : 1483)	NC score	0.016104 (rank : 1698)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1405	Shared Neighborhood Hits	176
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

FOXC2_HUMAN
θ value	1.81305 (rank : 1484)	NC score	0.001288 (rank : 1950)
Query Neighborhood Hits	1959	Target Neighborhood Hits	236	Shared Neighborhood Hits	87
SwissProt Accessions	Q99958	Gene names	FOXC2, FKHL14, MFH1
Domain Architecture
Description	Forkhead box protein C2 (Forkhead-related protein FKHL14) (Mesenchyme fork head protein 1) (MFH-1 protein) (Transcription factor FKH-14).

FOXK2_HUMAN
θ value	1.81305 (rank : 1485)	NC score	0.001611 (rank : 1941)
Query Neighborhood Hits	1959	Target Neighborhood Hits	190	Shared Neighborhood Hits	59
SwissProt Accessions	Q01167, Q13622, Q13623, Q13624	Gene names	FOXK2, ILF, ILF1
Domain Architecture
Description	Forkhead box protein K2 (Interleukin enhancer-binding factor 1) (Cellular transcription factor ILF-1).

GAK5_HUMAN
θ value	1.81305 (rank : 1486)	NC score	0.021761 (rank : 1612)
Query Neighborhood Hits	1959	Target Neighborhood Hits	429	Shared Neighborhood Hits	191
SwissProt Accessions	P62684	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K113 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GCFC_HUMAN
θ value	1.81305 (rank : 1487)	NC score	0.007899 (rank : 1825)
Query Neighborhood Hits	1959	Target Neighborhood Hits	86	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y5B6, Q9NYQ0	Gene names	GCFC, C21orf66
Domain Architecture	No domain graphic available
Description	GC-rich sequence DNA-binding factor homolog.

GGN_HUMAN
θ value	1.81305 (rank : 1488)	NC score	0.048930 (rank : 1371)
Query Neighborhood Hits	1959	Target Neighborhood Hits	269	Shared Neighborhood Hits	140
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GLI4_HUMAN
θ value	1.81305 (rank : 1489)	NC score	-0.027545 (rank : 2116)
Query Neighborhood Hits	1959	Target Neighborhood Hits	735	Shared Neighborhood Hits	48
SwissProt Accessions	P10075, Q96CK9	Gene names	GLI4, HKR4
Domain Architecture
Description	Zinc finger protein GLI4 (Krueppel-related zinc finger protein 4) (Protein HKR4).

HGFA_HUMAN
θ value	1.81305 (rank : 1490)	NC score	-0.009804 (rank : 2064)
Query Neighborhood Hits	1959	Target Neighborhood Hits	436	Shared Neighborhood Hits	41
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

HXA3_MOUSE
θ value	1.81305 (rank : 1491)	NC score	-0.003033 (rank : 2015)
Query Neighborhood Hits	1959	Target Neighborhood Hits	558	Shared Neighborhood Hits	150
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

IGSF8_HUMAN
θ value	1.81305 (rank : 1492)	NC score	0.044279 (rank : 1403)
Query Neighborhood Hits	1959	Target Neighborhood Hits	88	Shared Neighborhood Hits	41
SwissProt Accessions	Q969P0, Q8NG09, Q96DP4, Q9BTG9	Gene names	IGSF8, CD81P3, EWI2, KCT4
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 8 precursor (CD81 partner 3) (Glu- Trp-Ile EWI motif-containing protein 2) (EWI-2) (Keratinocytes- associated transmembrane protein 4) (KCT-4) (LIR-D1) (CD316 antigen).

IQEC2_HUMAN
θ value	1.81305 (rank : 1493)	NC score	0.017063 (rank : 1685)
Query Neighborhood Hits	1959	Target Neighborhood Hits	403	Shared Neighborhood Hits	156
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IQEC2_MOUSE
θ value	1.81305 (rank : 1494)	NC score	0.017398 (rank : 1681)
Query Neighborhood Hits	1959	Target Neighborhood Hits	417	Shared Neighborhood Hits	157
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IRS1_HUMAN
θ value	1.81305 (rank : 1495)	NC score	0.012809 (rank : 1745)
Query Neighborhood Hits	1959	Target Neighborhood Hits	109	Shared Neighborhood Hits	39
SwissProt Accessions	P35568	Gene names	IRS1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

K2002_HUMAN
θ value	1.81305 (rank : 1496)	NC score	0.322411 (rank : 926)
Query Neighborhood Hits	1959	Target Neighborhood Hits	274	Shared Neighborhood Hits	264
SwissProt Accessions	Q9H792, Q6ZS78, Q8NCM3	Gene names	KIAA2002
Domain Architecture	No domain graphic available
Description	Uncharacterized tyrosine-protein kinase KIAA2002 (EC 2.7.10.2).

KIFC2_HUMAN
θ value	1.81305 (rank : 1497)	NC score	-0.003725 (rank : 2023)
Query Neighborhood Hits	1959	Target Neighborhood Hits	237	Shared Neighborhood Hits	29
SwissProt Accessions	Q96AC6	Gene names	KIFC2
Domain Architecture
Description	Kinesin-like protein KIFC2.

LRCH4_HUMAN
θ value	1.81305 (rank : 1498)	NC score	0.013250 (rank : 1741)
Query Neighborhood Hits	1959	Target Neighborhood Hits	305	Shared Neighborhood Hits	58
SwissProt Accessions	O75427, Q8WV85, Q96ID0	Gene names	LRCH4, LRN, LRRN4
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 4 (Leucine-rich neuronal protein).

MADCA_HUMAN
θ value	1.81305 (rank : 1499)	NC score	0.061054 (rank : 1279)
Query Neighborhood Hits	1959	Target Neighborhood Hits	221	Shared Neighborhood Hits	125
SwissProt Accessions	Q13477, O60222, O75867	Gene names	MADCAM1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (hMAdCAM-1).

MAML1_HUMAN
θ value	1.81305 (rank : 1500)	NC score	0.017596 (rank : 1673)
Query Neighborhood Hits	1959	Target Neighborhood Hits	228	Shared Neighborhood Hits	93
SwissProt Accessions	Q92585, Q9NZ12	Gene names	MAML1, KIAA0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

MMP21_HUMAN
θ value	1.81305 (rank : 1501)	NC score	-0.002658 (rank : 2012)
Query Neighborhood Hits	1959	Target Neighborhood Hits	76	Shared Neighborhood Hits	15
SwissProt Accessions	Q8N119, Q8NG02	Gene names	MMP21
Domain Architecture	No domain graphic available
Description	Matrix metalloproteinase-21 precursor (EC 3.4.24.-) (MMP-21).

NPHP4_MOUSE
θ value	1.81305 (rank : 1502)	NC score	0.009265 (rank : 1802)
Query Neighborhood Hits	1959	Target Neighborhood Hits	62	Shared Neighborhood Hits	28
SwissProt Accessions	P59240	Gene names	Nphp4
Domain Architecture	No domain graphic available
Description	Nephrocystin-4 (Nephroretinin).

PAR10_HUMAN
θ value	1.81305 (rank : 1503)	NC score	0.003035 (rank : 1917)
Query Neighborhood Hits	1959	Target Neighborhood Hits	142	Shared Neighborhood Hits	27
SwissProt Accessions	Q53GL7, Q8N2I0, Q8WV05, Q96CH7	Gene names	PARP10
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 10 (EC 2.4.2.30) (PARP-10).

PGCA_HUMAN
θ value	1.81305 (rank : 1504)	NC score	0.011468 (rank : 1769)
Query Neighborhood Hits	1959	Target Neighborhood Hits	821	Shared Neighborhood Hits	205
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

PGFRL_MOUSE
θ value	1.81305 (rank : 1505)	NC score	0.137257 (rank : 1071)
Query Neighborhood Hits	1959	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	Q6PE55, Q3V182, Q9D0Z1	Gene names	Pdgfrl
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor receptor-like protein precursor.

PLCB3_HUMAN
θ value	1.81305 (rank : 1506)	NC score	0.018802 (rank : 1657)
Query Neighborhood Hits	1959	Target Neighborhood Hits	445	Shared Neighborhood Hits	72
SwissProt Accessions	Q01970	Gene names	PLCB3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

PPRB_HUMAN
θ value	1.81305 (rank : 1507)	NC score	0.041221 (rank : 1431)
Query Neighborhood Hits	1959	Target Neighborhood Hits	311	Shared Neighborhood Hits	122
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

PRAX_MOUSE
θ value	1.81305 (rank : 1508)	NC score	0.045487 (rank : 1395)
Query Neighborhood Hits	1959	Target Neighborhood Hits	199	Shared Neighborhood Hits	95
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

PSG11_HUMAN
θ value	1.81305 (rank : 1509)	NC score	0.164877 (rank : 1037)
Query Neighborhood Hits	1959	Target Neighborhood Hits	223	Shared Neighborhood Hits	191
SwissProt Accessions	Q9UQ72, Q13179, Q15242, Q9UNE4	Gene names	PSG11, PSG13
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 11 precursor (PSBG-11) (PSBG- 13).

RIMB1_HUMAN
θ value	1.81305 (rank : 1510)	NC score	0.051206 (rank : 1346)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1479	Shared Neighborhood Hits	341
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RIMS1_HUMAN
θ value	1.81305 (rank : 1511)	NC score	0.029657 (rank : 1512)
Query Neighborhood Hits	1959	Target Neighborhood Hits	437	Shared Neighborhood Hits	113
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

SAM68_MOUSE
θ value	1.81305 (rank : 1512)	NC score	0.010170 (rank : 1791)
Query Neighborhood Hits	1959	Target Neighborhood Hits	65	Shared Neighborhood Hits	21
SwissProt Accessions	Q60749, Q3U8T3, Q60735, Q99M33	Gene names	Khdrbs1
Domain Architecture	No domain graphic available
Description	KH domain-containing, RNA-binding, signal transduction-associated protein 1 (p21 Ras GTPase-activating protein-associated p62) (GAP- associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p68).

SYNPO_MOUSE
θ value	1.81305 (rank : 1513)	NC score	0.036325 (rank : 1466)
Query Neighborhood Hits	1959	Target Neighborhood Hits	242	Shared Neighborhood Hits	133
SwissProt Accessions	Q8CC35, Q99JI0	Gene names	Synpo, Kiaa1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

TBX10_MOUSE
θ value	1.81305 (rank : 1514)	NC score	-0.001543 (rank : 1996)
Query Neighborhood Hits	1959	Target Neighborhood Hits	47	Shared Neighborhood Hits	11
SwissProt Accessions	Q810F8, O54841, Q6QH75	Gene names	Tbx10, Tbx13, Tbx7
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX10 (T-box protein 10) (T-box protein 13) (MmTBX7).

TOIP1_HUMAN
θ value	1.81305 (rank : 1515)	NC score	0.013472 (rank : 1739)
Query Neighborhood Hits	1959	Target Neighborhood Hits	58	Shared Neighborhood Hits	20
SwissProt Accessions	Q5JTV8, Q5JTV6, Q8IZ65, Q9H8Y6, Q9HAJ1, Q9NV52, Q9Y3X5	Gene names	TOR1AIP1
Domain Architecture	No domain graphic available
Description	Torsin-1A-interacting protein 1.

TTC28_HUMAN
θ value	1.81305 (rank : 1516)	NC score	0.012462 (rank : 1753)
Query Neighborhood Hits	1959	Target Neighborhood Hits	271	Shared Neighborhood Hits	81
SwissProt Accessions	Q96AY4, O95928, O95929, Q9NTE4, Q9UG31, Q9UGG5, Q9UPV8, Q9Y3S5	Gene names	TTC28, KIAA1043
Domain Architecture
Description	Tetratricopeptide repeat protein 28 (TPR repeat protein 28).

ZN268_HUMAN
θ value	1.81305 (rank : 1517)	NC score	-0.027417 (rank : 2114)
Query Neighborhood Hits	1959	Target Neighborhood Hits	753	Shared Neighborhood Hits	47
SwissProt Accessions	Q14587, Q96RH4, Q9BZJ9	Gene names	ZNF268
Domain Architecture
Description	Zinc finger protein 268 (Zinc finger protein HZF3).

ZN645_HUMAN
θ value	1.81305 (rank : 1518)	NC score	0.036284 (rank : 1467)
Query Neighborhood Hits	1959	Target Neighborhood Hits	265	Shared Neighborhood Hits	108
SwissProt Accessions	Q8N7E2, Q6DJY9	Gene names	ZNF645
Domain Architecture	No domain graphic available
Description	Zinc finger protein 645.

ZO2_MOUSE
θ value	1.81305 (rank : 1519)	NC score	0.012448 (rank : 1754)
Query Neighborhood Hits	1959	Target Neighborhood Hits	296	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

ADA19_MOUSE
θ value	2.36792 (rank : 1520)	NC score	-0.004553 (rank : 2035)
Query Neighborhood Hits	1959	Target Neighborhood Hits	315	Shared Neighborhood Hits	52
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

ANR47_HUMAN
θ value	2.36792 (rank : 1521)	NC score	0.006801 (rank : 1849)
Query Neighborhood Hits	1959	Target Neighborhood Hits	369	Shared Neighborhood Hits	66
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

ATBF1_HUMAN
θ value	2.36792 (rank : 1522)	NC score	-0.013764 (rank : 2081)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1547	Shared Neighborhood Hits	250
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

CA065_HUMAN
θ value	2.36792 (rank : 1523)	NC score	0.036935 (rank : 1462)
Query Neighborhood Hits	1959	Target Neighborhood Hits	469	Shared Neighborhood Hits	85
SwissProt Accessions	Q8N715, Q8N746, Q8NA93	Gene names	C1orf65
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf65.

CA106_HUMAN
θ value	2.36792 (rank : 1524)	NC score	0.011574 (rank : 1768)
Query Neighborhood Hits	1959	Target Neighborhood Hits	124	Shared Neighborhood Hits	46
SwissProt Accessions	Q3KP66, Q9NV65, Q9NVI0	Gene names	C1orf106
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106.

CALX_HUMAN
θ value	2.36792 (rank : 1525)	NC score	0.008076 (rank : 1822)
Query Neighborhood Hits	1959	Target Neighborhood Hits	96	Shared Neighborhood Hits	29
SwissProt Accessions	P27824	Gene names	CANX
Domain Architecture
Description	Calnexin precursor (Major histocompatibility complex class I antigen- binding protein p88) (p90) (IP90).

CASC3_MOUSE
θ value	2.36792 (rank : 1526)	NC score	0.043868 (rank : 1409)
Query Neighborhood Hits	1959	Target Neighborhood Hits	333	Shared Neighborhood Hits	152
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

CJ078_MOUSE
θ value	2.36792 (rank : 1527)	NC score	0.061226 (rank : 1276)
Query Neighborhood Hits	1959	Target Neighborhood Hits	559	Shared Neighborhood Hits	214
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

CLGN_HUMAN
θ value	2.36792 (rank : 1528)	NC score	0.003828 (rank : 1901)
Query Neighborhood Hits	1959	Target Neighborhood Hits	111	Shared Neighborhood Hits	20
SwissProt Accessions	O14967	Gene names	CLGN
Domain Architecture
Description	Calmegin precursor.

CT055_MOUSE
θ value	2.36792 (rank : 1529)	NC score	0.015969 (rank : 1702)
Query Neighborhood Hits	1959	Target Neighborhood Hits	52	Shared Neighborhood Hits	33
SwissProt Accessions	Q8R184, Q8BQE5, Q8K024, Q8VEM7, Q9CU80	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf55 homolog.

CXAR_HUMAN
θ value	2.36792 (rank : 1530)	NC score	0.167001 (rank : 1034)
Query Neighborhood Hits	1959	Target Neighborhood Hits	245	Shared Neighborhood Hits	167
SwissProt Accessions	P78310, O00694, Q8WWT6, Q8WWT7, Q8WWT8, Q9UKV4	Gene names	CXADR, CAR
Domain Architecture
Description	Coxsackievirus and adenovirus receptor precursor (Coxsackievirus B- adenovirus receptor) (hCAR) (CVB3-binding protein) (HCVADR).

DIAP1_MOUSE
θ value	2.36792 (rank : 1531)	NC score	0.020910 (rank : 1630)
Query Neighborhood Hits	1959	Target Neighborhood Hits	839	Shared Neighborhood Hits	172
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

EHMT2_MOUSE
θ value	2.36792 (rank : 1532)	NC score	0.014815 (rank : 1719)
Query Neighborhood Hits	1959	Target Neighborhood Hits	750	Shared Neighborhood Hits	195
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

FBX42_MOUSE
θ value	2.36792 (rank : 1533)	NC score	0.006004 (rank : 1870)
Query Neighborhood Hits	1959	Target Neighborhood Hits	84	Shared Neighborhood Hits	25
SwissProt Accessions	Q6PDJ6, Q8CE76, Q99KY2	Gene names	Fbxo42
Domain Architecture	No domain graphic available
Description	F-box only protein 42.

FOXL1_HUMAN
θ value	2.36792 (rank : 1534)	NC score	-0.001868 (rank : 2002)
Query Neighborhood Hits	1959	Target Neighborhood Hits	114	Shared Neighborhood Hits	31
SwissProt Accessions	Q12952, Q9H242	Gene names	FOXL1, FKHL11, FREAC7
Domain Architecture
Description	Forkhead box protein L1 (Forkhead-related protein FKHL11) (Forkhead- related transcription factor 7) (FREAC-7).

GP152_HUMAN
θ value	2.36792 (rank : 1535)	NC score	0.002566 (rank : 1925)
Query Neighborhood Hits	1959	Target Neighborhood Hits	636	Shared Neighborhood Hits	157
SwissProt Accessions	Q8TDT2, Q86SM0	Gene names	GPR152, PGR5
Domain Architecture
Description	Probable G-protein coupled receptor 152 (G-protein coupled receptor PGR5).

HCN4_MOUSE
θ value	2.36792 (rank : 1536)	NC score	0.022953 (rank : 1597)
Query Neighborhood Hits	1959	Target Neighborhood Hits	284	Shared Neighborhood Hits	134
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

HMX2_MOUSE
θ value	2.36792 (rank : 1537)	NC score	-0.013385 (rank : 2076)
Query Neighborhood Hits	1959	Target Neighborhood Hits	354	Shared Neighborhood Hits	31
SwissProt Accessions	P43687, Q8R1Q2	Gene names	Hmx2, Nkx-5.2, Nkx5-2
Domain Architecture
Description	Homeobox protein HMX2 (Homeobox protein Nkx-5.2).

HN1L_HUMAN
θ value	2.36792 (rank : 1538)	NC score	0.017790 (rank : 1670)
Query Neighborhood Hits	1959	Target Neighborhood Hits	88	Shared Neighborhood Hits	54
SwissProt Accessions	Q9H910, Q6EIC7	Gene names	C16orf34, HN1L
Domain Architecture	No domain graphic available
Description	Hematological and neurological expressed 1-like protein (HN1-like protein).

IRAK1_MOUSE
θ value	2.36792 (rank : 1539)	NC score	0.675147 (rank : 666)
Query Neighborhood Hits	1959	Target Neighborhood Hits	784	Shared Neighborhood Hits	742
SwissProt Accessions	Q62406, Q6Y3Z5, Q6Y3Z6	Gene names	Irak1, Il1rak
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK).

K1949_HUMAN
θ value	2.36792 (rank : 1540)	NC score	0.016864 (rank : 1691)
Query Neighborhood Hits	1959	Target Neighborhood Hits	121	Shared Neighborhood Hits	50
SwissProt Accessions	Q6NYC8, Q68CK8, Q6ZUJ6, Q8NDQ4, Q8TF52, Q9BRL9	Gene names	KIAA1949
Domain Architecture	No domain graphic available
Description	Protein KIAA1949.

K2027_HUMAN
θ value	2.36792 (rank : 1541)	NC score	0.030813 (rank : 1505)
Query Neighborhood Hits	1959	Target Neighborhood Hits	194	Shared Neighborhood Hits	84
SwissProt Accessions	Q6ZVF9, Q8IVE4	Gene names	KIAA2027
Domain Architecture	No domain graphic available
Description	Protein KIAA2027.

KCNQ1_MOUSE
θ value	2.36792 (rank : 1542)	NC score	0.000688 (rank : 1960)
Query Neighborhood Hits	1959	Target Neighborhood Hits	175	Shared Neighborhood Hits	51
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNQ2_MOUSE
θ value	2.36792 (rank : 1543)	NC score	-0.000204 (rank : 1979)
Query Neighborhood Hits	1959	Target Neighborhood Hits	163	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Z351, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350	Gene names	Kcnq2, Kqt2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Potassium channel subunit alpha KvLQT2) (KQT-like 2).

KLD8B_HUMAN
θ value	2.36792 (rank : 1544)	NC score	-0.003335 (rank : 2019)
Query Neighborhood Hits	1959	Target Neighborhood Hits	80	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IXV7	Gene names	KLHDC8B
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 8B.

KLF17_MOUSE
θ value	2.36792 (rank : 1545)	NC score	-0.025682 (rank : 2107)
Query Neighborhood Hits	1959	Target Neighborhood Hits	684	Shared Neighborhood Hits	48
SwissProt Accessions	Q8CFA7, Q3UT30, Q6P233, Q9D351	Gene names	Klf17, Gzf, Zfp393, Znf393
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 17 (Zinc finger protein 393) (Germ cell-specific zinc finger protein).

MAGD4_HUMAN
θ value	2.36792 (rank : 1546)	NC score	0.014537 (rank : 1722)
Query Neighborhood Hits	1959	Target Neighborhood Hits	338	Shared Neighborhood Hits	160
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

MLKL_MOUSE
θ value	2.36792 (rank : 1547)	NC score	0.620402 (rank : 766)
Query Neighborhood Hits	1959	Target Neighborhood Hits	707	Shared Neighborhood Hits	681
SwissProt Accessions	Q9D2Y4, Q8CIJ5	Gene names	Mlkl
Domain Architecture	No domain graphic available
Description	Mixed lineage kinase domain-like protein.

NIPBL_HUMAN
θ value	2.36792 (rank : 1548)	NC score	0.050335 (rank : 1354)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1311	Shared Neighborhood Hits	312
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

NOL1_HUMAN
θ value	2.36792 (rank : 1549)	NC score	0.013714 (rank : 1737)
Query Neighborhood Hits	1959	Target Neighborhood Hits	74	Shared Neighborhood Hits	23
SwissProt Accessions	P46087	Gene names	NOL1
Domain Architecture
Description	Proliferating-cell nucleolar antigen p120 (Proliferation-associated nucleolar protein p120).

NPFF1_HUMAN
θ value	2.36792 (rank : 1550)	NC score	-0.030032 (rank : 2119)
Query Neighborhood Hits	1959	Target Neighborhood Hits	858	Shared Neighborhood Hits	5
SwissProt Accessions	Q9GZQ6, Q8NGR0, Q96RN3	Gene names	NPFFR1, GPR147, NPFF1
Domain Architecture
Description	Neuropeptide FF receptor 1 (G-protein coupled receptor 147) (RFamide- related peptide receptor OT7T022).

PA24B_MOUSE
θ value	2.36792 (rank : 1551)	NC score	0.010250 (rank : 1787)
Query Neighborhood Hits	1959	Target Neighborhood Hits	102	Shared Neighborhood Hits	17
SwissProt Accessions	Q4QQM1, Q80VV8, Q91W88	Gene names	Pla2g4b
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

PECA1_HUMAN
θ value	2.36792 (rank : 1552)	NC score	0.149107 (rank : 1060)
Query Neighborhood Hits	1959	Target Neighborhood Hits	178	Shared Neighborhood Hits	140
SwissProt Accessions	P16284, Q6LDA9, Q8TBH1, Q96RF5, Q96RF6, Q9NP65, Q9NPB7, Q9NPG9, Q9NQS9, Q9NQT0, Q9NQT1, Q9NQT2	Gene names	PECAM1
Domain Architecture
Description	Platelet endothelial cell adhesion molecule precursor (PECAM-1) (EndoCAM) (GPIIA') (CD31 antigen).

PER3_HUMAN
θ value	2.36792 (rank : 1553)	NC score	0.026036 (rank : 1545)
Query Neighborhood Hits	1959	Target Neighborhood Hits	479	Shared Neighborhood Hits	192
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

PHLPP_HUMAN
θ value	2.36792 (rank : 1554)	NC score	0.025536 (rank : 1556)
Query Neighborhood Hits	1959	Target Neighborhood Hits	604	Shared Neighborhood Hits	178
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

PKHA6_HUMAN
θ value	2.36792 (rank : 1555)	NC score	0.023192 (rank : 1592)
Query Neighborhood Hits	1959	Target Neighborhood Hits	556	Shared Neighborhood Hits	160
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PLRG1_MOUSE
θ value	2.36792 (rank : 1556)	NC score	-0.013633 (rank : 2079)
Query Neighborhood Hits	1959	Target Neighborhood Hits	308	Shared Neighborhood Hits	12
SwissProt Accessions	Q922V4, O55039	Gene names	Plrg1
Domain Architecture
Description	Pleiotropic regulator 1.

PRGC2_HUMAN
θ value	2.36792 (rank : 1557)	NC score	0.023466 (rank : 1586)
Query Neighborhood Hits	1959	Target Neighborhood Hits	272	Shared Neighborhood Hits	105
SwissProt Accessions	Q86YN6, Q86YN3, Q86YN4, Q86YN5, Q8N1N9, Q8TDE4, Q8TDE5	Gene names	PPARGC1B, PERC, PGC1, PGC1B, PPARGC1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta) (PGC-1-related estrogen receptor alpha coactivator) (PPARGC-1-beta) (PGC-1-beta).

PSG7_HUMAN
θ value	2.36792 (rank : 1558)	NC score	0.166483 (rank : 1035)
Query Neighborhood Hits	1959	Target Neighborhood Hits	239	Shared Neighborhood Hits	194
SwissProt Accessions	Q13046, Q15232	Gene names	PSG7
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 7 precursor (PSBG-7).

PYGO1_HUMAN
θ value	2.36792 (rank : 1559)	NC score	0.008866 (rank : 1809)
Query Neighborhood Hits	1959	Target Neighborhood Hits	90	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y3Y4	Gene names	PYGO1
Domain Architecture
Description	Pygopus homolog 1.

RANB3_HUMAN
θ value	2.36792 (rank : 1560)	NC score	0.014084 (rank : 1727)
Query Neighborhood Hits	1959	Target Neighborhood Hits	117	Shared Neighborhood Hits	46
SwissProt Accessions	Q9H6Z4, O60405, O75759, O75760, Q9BT47, Q9UG74	Gene names	RANBP3
Domain Architecture	No domain graphic available
Description	Ran-binding protein 3 (RanBP3).

RTN2_HUMAN
θ value	2.36792 (rank : 1561)	NC score	0.010734 (rank : 1783)
Query Neighborhood Hits	1959	Target Neighborhood Hits	59	Shared Neighborhood Hits	28
SwissProt Accessions	O75298, O60509, Q7RTM6, Q7RTN1, Q7RTN2	Gene names	RTN2, NSPL1
Domain Architecture
Description	Reticulon-2 (Neuroendocrine-specific protein-like 1) (NSP-like protein 1) (NSPLI).

SCMH1_MOUSE
θ value	2.36792 (rank : 1562)	NC score	0.007823 (rank : 1828)
Query Neighborhood Hits	1959	Target Neighborhood Hits	87	Shared Neighborhood Hits	36
SwissProt Accessions	Q8K214, Q9JME0	Gene names	Scmh1
Domain Architecture	No domain graphic available
Description	Polycomb protein SCMH1 (Sex comb on midleg homolog 1).

SETD2_HUMAN
θ value	2.36792 (rank : 1563)	NC score	0.015716 (rank : 1706)
Query Neighborhood Hits	1959	Target Neighborhood Hits	412	Shared Neighborhood Hits	103
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SFR11_HUMAN
θ value	2.36792 (rank : 1564)	NC score	0.027958 (rank : 1527)
Query Neighborhood Hits	1959	Target Neighborhood Hits	246	Shared Neighborhood Hits	62
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

SHC1_HUMAN
θ value	2.36792 (rank : 1565)	NC score	0.038761 (rank : 1450)
Query Neighborhood Hits	1959	Target Neighborhood Hits	170	Shared Neighborhood Hits	63
SwissProt Accessions	P29353, O15290, Q8N4K5, Q96CL1	Gene names	SHC1, SHC, SHCA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

SOX18_HUMAN
θ value	2.36792 (rank : 1566)	NC score	-0.001981 (rank : 2003)
Query Neighborhood Hits	1959	Target Neighborhood Hits	106	Shared Neighborhood Hits	23
SwissProt Accessions	P35713, Q9NPH8	Gene names	SOX18
Domain Architecture
Description	Transcription factor SOX-18.

SYN2_HUMAN
θ value	2.36792 (rank : 1567)	NC score	0.030338 (rank : 1508)
Query Neighborhood Hits	1959	Target Neighborhood Hits	213	Shared Neighborhood Hits	113
SwissProt Accessions	Q92777	Gene names	SYN2
Domain Architecture
Description	Synapsin-2 (Synapsin II).

TAF3_HUMAN
θ value	2.36792 (rank : 1568)	NC score	0.038703 (rank : 1454)
Query Neighborhood Hits	1959	Target Neighborhood Hits	568	Shared Neighborhood Hits	150
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TBC10_HUMAN
θ value	2.36792 (rank : 1569)	NC score	0.006356 (rank : 1860)
Query Neighborhood Hits	1959	Target Neighborhood Hits	64	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BXI6, O76053, Q543A2	Gene names	TBC1D10A, EPI64, TBC1D10
Domain Architecture
Description	TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa) (EPI64 protein).

TBC10_MOUSE
θ value	2.36792 (rank : 1570)	NC score	0.007282 (rank : 1837)
Query Neighborhood Hits	1959	Target Neighborhood Hits	94	Shared Neighborhood Hits	36
SwissProt Accessions	P58802	Gene names	Tbc1d10a, Epi64, Tbc1d10
Domain Architecture
Description	TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa) (EPI64 protein).

UNC5C_HUMAN
θ value	2.36792 (rank : 1571)	NC score	0.120169 (rank : 1098)
Query Neighborhood Hits	1959	Target Neighborhood Hits	226	Shared Neighborhood Hits	139
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

XPC_HUMAN
θ value	2.36792 (rank : 1572)	NC score	0.010209 (rank : 1788)
Query Neighborhood Hits	1959	Target Neighborhood Hits	64	Shared Neighborhood Hits	23
SwissProt Accessions	Q01831, Q96AX0	Gene names	XPC, XPCC
Domain Architecture
Description	DNA-repair protein complementing XP-C cells (Xeroderma pigmentosum group C-complementing protein) (p125).

3BP2_HUMAN
θ value	3.0926 (rank : 1573)	NC score	0.031247 (rank : 1503)
Query Neighborhood Hits	1959	Target Neighborhood Hits	296	Shared Neighborhood Hits	131
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

AFAD_HUMAN
θ value	3.0926 (rank : 1574)	NC score	0.023609 (rank : 1582)
Query Neighborhood Hits	1959	Target Neighborhood Hits	689	Shared Neighborhood Hits	136
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

AFF2_MOUSE
θ value	3.0926 (rank : 1575)	NC score	0.022367 (rank : 1607)
Query Neighborhood Hits	1959	Target Neighborhood Hits	225	Shared Neighborhood Hits	100
SwissProt Accessions	O55112	Gene names	Aff2, Fmr2, Ox19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation protein 2 homolog) (Protein FMR-2) (FMR2P) (Protein Ox19).

AT11C_HUMAN
θ value	3.0926 (rank : 1576)	NC score	-0.003889 (rank : 2024)
Query Neighborhood Hits	1959	Target Neighborhood Hits	89	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NB49, Q5JT69, Q5JT70, Q5JT71, Q5JT72, Q5JT73, Q6ZND5, Q6ZU50, Q6ZUP7, Q70IJ9, Q70IK0, Q8WX24	Gene names	ATP11C, ATPIG, ATPIQ
Domain Architecture	No domain graphic available
Description	Probable phospholipid-transporting ATPase IG (EC 3.6.3.1) (ATPase class I type 11C) (ATPase IG) (ATPase IQ) (ATPase class VI type 11C).

ATBF1_MOUSE
θ value	3.0926 (rank : 1577)	NC score	-0.005170 (rank : 2039)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1841	Shared Neighborhood Hits	325
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

BFSP1_HUMAN
θ value	3.0926 (rank : 1578)	NC score	0.003063 (rank : 1915)
Query Neighborhood Hits	1959	Target Neighborhood Hits	508	Shared Neighborhood Hits	58
SwissProt Accessions	Q12934, O43595, O76034, Q9HBX4	Gene names	BFSP1
Domain Architecture
Description	Filensin (Beaded filament structural protein 1) (Lens fiber cell beaded-filament structural protein CP 115) (CP115) (Lens intermediate filament-like heavy) (LIFL-H).

CCD1A_HUMAN
θ value	3.0926 (rank : 1579)	NC score	0.015479 (rank : 1712)
Query Neighborhood Hits	1959	Target Neighborhood Hits	123	Shared Neighborhood Hits	54
SwissProt Accessions	Q6P1N0, Q7Z435, Q86XV0, Q8NF89, Q9H603, Q9NXI1	Gene names	CC2D1A
Domain Architecture	No domain graphic available
Description	Coiled-coil and C2 domain-containing protein 1A (Five repressor element under dual repression-binding protein 1) (FRE under dual repression-binding protein 1) (Freud-1) (Putative NF-kappa-B- activating protein 023N).

CCD96_HUMAN
θ value	3.0926 (rank : 1580)	NC score	0.021456 (rank : 1619)
Query Neighborhood Hits	1959	Target Neighborhood Hits	595	Shared Neighborhood Hits	123
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CHD3_HUMAN
θ value	3.0926 (rank : 1581)	NC score	-0.000814 (rank : 1986)
Query Neighborhood Hits	1959	Target Neighborhood Hits	397	Shared Neighborhood Hits	79
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

CSPG3_MOUSE
θ value	3.0926 (rank : 1582)	NC score	0.001849 (rank : 1938)
Query Neighborhood Hits	1959	Target Neighborhood Hits	657	Shared Neighborhood Hits	141
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

DBPA_MOUSE
θ value	3.0926 (rank : 1583)	NC score	0.008406 (rank : 1815)
Query Neighborhood Hits	1959	Target Neighborhood Hits	64	Shared Neighborhood Hits	31
SwissProt Accessions	Q9JKB3, Q80WG4, Q9EQF7, Q9EQF8	Gene names	Csda, Msy4, Ybx3
Domain Architecture	No domain graphic available
Description	DNA-binding protein A (Cold shock domain-containing protein A) (Y-box protein 3).

DGKK_HUMAN
θ value	3.0926 (rank : 1584)	NC score	0.055329 (rank : 1315)
Query Neighborhood Hits	1959	Target Neighborhood Hits	378	Shared Neighborhood Hits	177
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

DIP2A_MOUSE
θ value	3.0926 (rank : 1585)	NC score	0.005308 (rank : 1881)
Query Neighborhood Hits	1959	Target Neighborhood Hits	32	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BWT5, Q8CHI0	Gene names	Dip2a, Dip2, Kiaa0184
Domain Architecture
Description	Disco-interacting protein 2 homolog A.

DYN1_HUMAN
θ value	3.0926 (rank : 1586)	NC score	0.017356 (rank : 1682)
Query Neighborhood Hits	1959	Target Neighborhood Hits	216	Shared Neighborhood Hits	104
SwissProt Accessions	Q05193	Gene names	DNM1, DNM
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

DYN1_MOUSE
θ value	3.0926 (rank : 1587)	NC score	0.012343 (rank : 1755)
Query Neighborhood Hits	1959	Target Neighborhood Hits	168	Shared Neighborhood Hits	73
SwissProt Accessions	P39053, Q61358, Q61359, Q61360, Q8JZZ4, Q9CSY7, Q9QXX1	Gene names	Dnm1, Dnm
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

EMIL2_HUMAN
θ value	3.0926 (rank : 1588)	NC score	0.001156 (rank : 1953)
Query Neighborhood Hits	1959	Target Neighborhood Hits	573	Shared Neighborhood Hits	98
SwissProt Accessions	Q9BXX0, Q8NBH3, Q96JQ4	Gene names	EMILIN2
Domain Architecture
Description	EMILIN-2 precursor (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Protein FOAP-10).

ETV3_MOUSE
θ value	3.0926 (rank : 1589)	NC score	0.001383 (rank : 1947)
Query Neighborhood Hits	1959	Target Neighborhood Hits	128	Shared Neighborhood Hits	43
SwissProt Accessions	Q8R4Z4, Q9QZW1	Gene names	Etv3, Mets, Pe1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

GOGA3_HUMAN
θ value	3.0926 (rank : 1590)	NC score	0.013728 (rank : 1736)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1317	Shared Neighborhood Hits	169
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

HNF3B_MOUSE
θ value	3.0926 (rank : 1591)	NC score	-0.001329 (rank : 1995)
Query Neighborhood Hits	1959	Target Neighborhood Hits	112	Shared Neighborhood Hits	31
SwissProt Accessions	P35583, Q60602	Gene names	Foxa2, Hnf3b, Tcf-3b, Tcf3b
Domain Architecture
Description	Hepatocyte nuclear factor 3-beta (HNF-3B) (Forkhead box protein A2).

HXA3_HUMAN
θ value	3.0926 (rank : 1592)	NC score	-0.003524 (rank : 2020)
Query Neighborhood Hits	1959	Target Neighborhood Hits	535	Shared Neighborhood Hits	135
SwissProt Accessions	O43365	Gene names	HOXA3, HOX1E
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1E).

JAM1_MOUSE
θ value	3.0926 (rank : 1593)	NC score	0.278816 (rank : 969)
Query Neighborhood Hits	1959	Target Neighborhood Hits	287	Shared Neighborhood Hits	221
SwissProt Accessions	O88792	Gene names	F11r, Jam1, Jcam, Jcam1
Domain Architecture
Description	Junctional adhesion molecule A precursor (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (CD321 antigen).

JAML1_MOUSE
θ value	3.0926 (rank : 1594)	NC score	0.101484 (rank : 1126)
Query Neighborhood Hits	1959	Target Neighborhood Hits	185	Shared Neighborhood Hits	110
SwissProt Accessions	Q80UL9, Q5DTC4	Gene names	Amica1, Gm638, Jaml
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule-like precursor (mCrea7).

JIP1_HUMAN
θ value	3.0926 (rank : 1595)	NC score	0.025637 (rank : 1555)
Query Neighborhood Hits	1959	Target Neighborhood Hits	271	Shared Neighborhood Hits	120
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

JIP2_HUMAN
θ value	3.0926 (rank : 1596)	NC score	0.027210 (rank : 1532)
Query Neighborhood Hits	1959	Target Neighborhood Hits	288	Shared Neighborhood Hits	106
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

K0310_HUMAN
θ value	3.0926 (rank : 1597)	NC score	0.044152 (rank : 1406)
Query Neighborhood Hits	1959	Target Neighborhood Hits	420	Shared Neighborhood Hits	201
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

K1683_HUMAN
θ value	3.0926 (rank : 1598)	NC score	0.049491 (rank : 1366)
Query Neighborhood Hits	1959	Target Neighborhood Hits	240	Shared Neighborhood Hits	116
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

KLF12_MOUSE
θ value	3.0926 (rank : 1599)	NC score	-0.024218 (rank : 2100)
Query Neighborhood Hits	1959	Target Neighborhood Hits	721	Shared Neighborhood Hits	60
SwissProt Accessions	O35738	Gene names	Klf12, Ap2rep
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 12 (Transcriptional repressor AP-2rep).

KLF13_HUMAN
θ value	3.0926 (rank : 1600)	NC score	-0.024948 (rank : 2103)
Query Neighborhood Hits	1959	Target Neighborhood Hits	739	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Y2Y9, Q9Y356	Gene names	KLF13, BTEB3, NSLP1
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 13 (Transcription factor BTEB3) (Basic transcription element-binding protein 3) (BTE-binding protein 3) (RANTES factor of late activated T-lymphocytes 1) (RFLAT-1) (Transcription factor NSLP1) (Novel Sp1-like zinc finger transcription factor 1).

LIPA3_HUMAN
θ value	3.0926 (rank : 1601)	NC score	0.009266 (rank : 1801)
Query Neighborhood Hits	1959	Target Neighborhood Hits	828	Shared Neighborhood Hits	99
SwissProt Accessions	O75145, Q9H8B5, Q9UEW4	Gene names	PPFIA3, KIAA0654
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

LRC41_HUMAN
θ value	3.0926 (rank : 1602)	NC score	0.012502 (rank : 1752)
Query Neighborhood Hits	1959	Target Neighborhood Hits	51	Shared Neighborhood Hits	15
SwissProt Accessions	Q15345, Q71RA8, Q9BSM0	Gene names	LRRC41, MUF1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 41 (Protein Muf1).

MED12_HUMAN
θ value	3.0926 (rank : 1603)	NC score	0.020740 (rank : 1633)
Query Neighborhood Hits	1959	Target Neighborhood Hits	262	Shared Neighborhood Hits	63
SwissProt Accessions	Q93074, O15410, O75557, Q9UHV6, Q9UND7	Gene names	MED12, ARC240, CAGH45, HOPA, KIAA0192, TNRC11, TRAP230
Domain Architecture	No domain graphic available
Description	Mediator of RNA polymerase II transcription subunit 12 (Thyroid hormone receptor-associated protein complex 230 kDa component) (Trap230) (Activator-recruited cofactor 240 kDa component) (ARC240) (CAG repeat protein 45) (OPA-containing protein) (Trinucleotide repeat-containing gene 11 protein).

MTR1L_HUMAN
θ value	3.0926 (rank : 1604)	NC score	-0.023201 (rank : 2096)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1180	Shared Neighborhood Hits	149
SwissProt Accessions	Q13585	Gene names	GPR50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).

NBEA_MOUSE
θ value	3.0926 (rank : 1605)	NC score	0.000478 (rank : 1963)
Query Neighborhood Hits	1959	Target Neighborhood Hits	225	Shared Neighborhood Hits	29
SwissProt Accessions	Q9EPN1, Q8C931, Q9EPM9, Q9EPN0, Q9WVM9	Gene names	Nbea, Lyst2
Domain Architecture
Description	Protein neurobeachin (Lysosomal-trafficking regulator 2).

PB1_HUMAN
θ value	3.0926 (rank : 1606)	NC score	0.003344 (rank : 1909)
Query Neighborhood Hits	1959	Target Neighborhood Hits	261	Shared Neighborhood Hits	58
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

PCQAP_MOUSE
θ value	3.0926 (rank : 1607)	NC score	0.049869 (rank : 1360)
Query Neighborhood Hits	1959	Target Neighborhood Hits	506	Shared Neighborhood Hits	166
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

PKHA4_HUMAN
θ value	3.0926 (rank : 1608)	NC score	0.022493 (rank : 1604)
Query Neighborhood Hits	1959	Target Neighborhood Hits	283	Shared Neighborhood Hits	109
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PRRT1_MOUSE
θ value	3.0926 (rank : 1609)	NC score	0.022806 (rank : 1601)
Query Neighborhood Hits	1959	Target Neighborhood Hits	102	Shared Neighborhood Hits	48
SwissProt Accessions	O35449	Gene names	Prrt1, Ng5
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 1.

PTPRU_HUMAN
θ value	3.0926 (rank : 1610)	NC score	0.087000 (rank : 1149)
Query Neighborhood Hits	1959	Target Neighborhood Hits	237	Shared Neighborhood Hits	129
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

PVRL3_MOUSE
θ value	3.0926 (rank : 1611)	NC score	0.143248 (rank : 1066)
Query Neighborhood Hits	1959	Target Neighborhood Hits	212	Shared Neighborhood Hits	149
SwissProt Accessions	Q9JLB9, Q9D006, Q9JLB7, Q9JLB8	Gene names	Pvrl3
Domain Architecture	No domain graphic available
Description	Poliovirus receptor-related protein 3 precursor (Cell adhesion molecule nectin-3) (Nectin-3) (CDw113 antigen).

PZRN3_MOUSE
θ value	3.0926 (rank : 1612)	NC score	-0.003690 (rank : 2022)
Query Neighborhood Hits	1959	Target Neighborhood Hits	447	Shared Neighborhood Hits	61
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

SEM4D_MOUSE
θ value	3.0926 (rank : 1613)	NC score	0.008705 (rank : 1813)
Query Neighborhood Hits	1959	Target Neighborhood Hits	143	Shared Neighborhood Hits	55
SwissProt Accessions	O09126	Gene names	Sema4d, Semacl2, Semaj
Domain Architecture
Description	Semaphorin-4D precursor (Semaphorin J) (Sema J) (Semaphorin C-like 2) (M-Sema G).

SHAN1_HUMAN
θ value	3.0926 (rank : 1614)	NC score	0.039915 (rank : 1442)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1041	Shared Neighborhood Hits	293
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SHC2_HUMAN
θ value	3.0926 (rank : 1615)	NC score	0.038883 (rank : 1449)
Query Neighborhood Hits	1959	Target Neighborhood Hits	170	Shared Neighborhood Hits	60
SwissProt Accessions	P98077, O60230, Q9NPL5, Q9UCX4	Gene names	SHC2, SCK, SHCB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck).

SIN3A_HUMAN
θ value	3.0926 (rank : 1616)	NC score	0.015266 (rank : 1714)
Query Neighborhood Hits	1959	Target Neighborhood Hits	180	Shared Neighborhood Hits	87
SwissProt Accessions	Q96ST3, Q8N8N4, Q8NC83, Q8WV18, Q96L98, Q9UFQ1	Gene names	SIN3A
Domain Architecture
Description	Paired amphipathic helix protein Sin3a (Transcriptional corepressor Sin3a) (Histone deacetylase complex subunit Sin3a).

SIX5_HUMAN
θ value	3.0926 (rank : 1617)	NC score	0.003917 (rank : 1897)
Query Neighborhood Hits	1959	Target Neighborhood Hits	386	Shared Neighborhood Hits	80
SwissProt Accessions	Q8N196	Gene names	SIX5, DMAHP
Domain Architecture	No domain graphic available
Description	Homeobox protein SIX5 (DM locus-associated homeodomain protein).

SL9A1_MOUSE
θ value	3.0926 (rank : 1618)	NC score	0.002001 (rank : 1933)
Query Neighborhood Hits	1959	Target Neighborhood Hits	32	Shared Neighborhood Hits	6
SwissProt Accessions	Q61165	Gene names	Slc9a1, Nhe1
Domain Architecture
Description	Sodium/hydrogen exchanger 1 (Na(+)/H(+) exchanger 1) (NHE-1) (Solute carrier family 9 member 1).

SNPC4_HUMAN
θ value	3.0926 (rank : 1619)	NC score	0.049446 (rank : 1367)
Query Neighborhood Hits	1959	Target Neighborhood Hits	589	Shared Neighborhood Hits	263
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

SNPC4_MOUSE
θ value	3.0926 (rank : 1620)	NC score	0.018393 (rank : 1664)
Query Neighborhood Hits	1959	Target Neighborhood Hits	237	Shared Neighborhood Hits	94
SwissProt Accessions	Q8BP86, Q6PGG7, Q80UG9, Q810L1	Gene names	Snapc4
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit).

SOX5_HUMAN
θ value	3.0926 (rank : 1621)	NC score	0.003791 (rank : 1902)
Query Neighborhood Hits	1959	Target Neighborhood Hits	219	Shared Neighborhood Hits	40
SwissProt Accessions	P35711, Q86UK8, Q8J017, Q8J018, Q8J019, Q8J020, Q8N1D9, Q8N7E0, Q8TEA4	Gene names	SOX5
Domain Architecture
Description	Transcription factor SOX-5.

SOX5_MOUSE
θ value	3.0926 (rank : 1622)	NC score	0.002962 (rank : 1920)
Query Neighborhood Hits	1959	Target Neighborhood Hits	196	Shared Neighborhood Hits	37
SwissProt Accessions	P35710, O88184, O89018	Gene names	Sox5, Sox-5
Domain Architecture
Description	Transcription factor SOX-5.

SYP2L_MOUSE
θ value	3.0926 (rank : 1623)	NC score	0.029200 (rank : 1517)
Query Neighborhood Hits	1959	Target Neighborhood Hits	289	Shared Neighborhood Hits	114
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

TAF4_HUMAN
θ value	3.0926 (rank : 1624)	NC score	0.069385 (rank : 1222)
Query Neighborhood Hits	1959	Target Neighborhood Hits	687	Shared Neighborhood Hits	263
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

TPO_MOUSE
θ value	3.0926 (rank : 1625)	NC score	0.026322 (rank : 1541)
Query Neighborhood Hits	1959	Target Neighborhood Hits	258	Shared Neighborhood Hits	110
SwissProt Accessions	P40226	Gene names	Thpo
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

TRIPC_HUMAN
θ value	3.0926 (rank : 1626)	NC score	0.010976 (rank : 1776)
Query Neighborhood Hits	1959	Target Neighborhood Hits	319	Shared Neighborhood Hits	89
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

VSIG4_HUMAN
θ value	3.0926 (rank : 1627)	NC score	0.232804 (rank : 1001)
Query Neighborhood Hits	1959	Target Neighborhood Hits	236	Shared Neighborhood Hits	188
SwissProt Accessions	Q9Y279, Q6UXI4	Gene names	VSIG4, Z39IG
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 4 precursor (Protein Z39Ig).

WASF4_HUMAN
θ value	3.0926 (rank : 1628)	NC score	0.035231 (rank : 1473)
Query Neighborhood Hits	1959	Target Neighborhood Hits	282	Shared Neighborhood Hits	153
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

YETS2_MOUSE
θ value	3.0926 (rank : 1629)	NC score	0.020847 (rank : 1631)
Query Neighborhood Hits	1959	Target Neighborhood Hits	278	Shared Neighborhood Hits	106
SwissProt Accessions	Q3TUF7, Q6PGF8, Q80TI2, Q8CG86	Gene names	Yeats2, Kiaa1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

ZFP38_HUMAN
θ value	3.0926 (rank : 1630)	NC score	-0.027356 (rank : 2113)
Query Neighborhood Hits	1959	Target Neighborhood Hits	766	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y5A6, Q9H0B5	Gene names	ZNF38, ZFP38, ZSCAN21
Domain Architecture
Description	Zinc finger protein 38 homolog (Zfp-38) (Zinc finger and SCAN domain- containing protein 21) (NY-REN-21 antigen).

ZN687_MOUSE
θ value	3.0926 (rank : 1631)	NC score	-0.016349 (rank : 2089)
Query Neighborhood Hits	1959	Target Neighborhood Hits	913	Shared Neighborhood Hits	145
SwissProt Accessions	Q9D2D7, Q6PAP3, Q6ZPQ9	Gene names	Znf687, Kiaa1441, Zfp687
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

ACD_HUMAN
θ value	4.03905 (rank : 1632)	NC score	0.032023 (rank : 1498)
Query Neighborhood Hits	1959	Target Neighborhood Hits	143	Shared Neighborhood Hits	80
SwissProt Accessions	Q96AP0, Q562H5, Q9H8F9	Gene names	ACD, PIP1, PTOP
Domain Architecture	No domain graphic available
Description	Adrenocortical dysplasia protein homolog (POT1 and TIN2-interacting protein).

ACINU_HUMAN
θ value	4.03905 (rank : 1633)	NC score	0.053028 (rank : 1328)
Query Neighborhood Hits	1959	Target Neighborhood Hits	828	Shared Neighborhood Hits	199
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

ARHGF_HUMAN
θ value	4.03905 (rank : 1634)	NC score	0.019965 (rank : 1642)
Query Neighborhood Hits	1959	Target Neighborhood Hits	214	Shared Neighborhood Hits	92
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

ATX7_HUMAN
θ value	4.03905 (rank : 1635)	NC score	0.028980 (rank : 1518)
Query Neighborhood Hits	1959	Target Neighborhood Hits	351	Shared Neighborhood Hits	163
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

BAI1_MOUSE
θ value	4.03905 (rank : 1636)	NC score	0.009182 (rank : 1804)
Query Neighborhood Hits	1959	Target Neighborhood Hits	340	Shared Neighborhood Hits	101
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI2_HUMAN
θ value	4.03905 (rank : 1637)	NC score	0.006421 (rank : 1857)
Query Neighborhood Hits	1959	Target Neighborhood Hits	332	Shared Neighborhood Hits	76
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BSCL2_HUMAN
θ value	4.03905 (rank : 1638)	NC score	0.010816 (rank : 1779)
Query Neighborhood Hits	1959	Target Neighborhood Hits	148	Shared Neighborhood Hits	34
SwissProt Accessions	Q96G97, Q96SV1, Q9BSQ0	Gene names	BSCL2
Domain Architecture	No domain graphic available
Description	Seipin (Bernardinelli-Seip congenital lipodystrophy type 2 protein).

BTNL1_MOUSE
θ value	4.03905 (rank : 1639)	NC score	0.034590 (rank : 1476)
Query Neighborhood Hits	1959	Target Neighborhood Hits	151	Shared Neighborhood Hits	76
SwissProt Accessions	Q7TST0, O70356	Gene names	Btnl1, Btnl3, Gm316, Ng10
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 1 precursor.

CAC1A_HUMAN
θ value	4.03905 (rank : 1640)	NC score	0.008707 (rank : 1812)
Query Neighborhood Hits	1959	Target Neighborhood Hits	387	Shared Neighborhood Hits	128
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAN12_HUMAN
θ value	4.03905 (rank : 1641)	NC score	-0.001677 (rank : 1999)
Query Neighborhood Hits	1959	Target Neighborhood Hits	47	Shared Neighborhood Hits	5
SwissProt Accessions	Q6ZSI9	Gene names	CAPN12
Domain Architecture	No domain graphic available
Description	Calpain-12 (EC 3.4.22.-).

CD166_HUMAN
θ value	4.03905 (rank : 1642)	NC score	0.210631 (rank : 1007)
Query Neighborhood Hits	1959	Target Neighborhood Hits	247	Shared Neighborhood Hits	183
SwissProt Accessions	Q13740, O60892	Gene names	ALCAM, MEMD
Domain Architecture
Description	CD166 antigen precursor (Activated leukocyte-cell adhesion molecule) (ALCAM).

CDX4_MOUSE
θ value	4.03905 (rank : 1643)	NC score	-0.013796 (rank : 2082)
Query Neighborhood Hits	1959	Target Neighborhood Hits	378	Shared Neighborhood Hits	47
SwissProt Accessions	Q07424	Gene names	Cdx4, Cdx-4
Domain Architecture
Description	Homeobox protein CDX-4 (Caudal-type homeobox protein 4).

CEAM6_HUMAN
θ value	4.03905 (rank : 1644)	NC score	0.202237 (rank : 1009)
Query Neighborhood Hits	1959	Target Neighborhood Hits	308	Shared Neighborhood Hits	229
SwissProt Accessions	P40199, Q14920	Gene names	CEACAM6, NCA
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 6 precursor (Normal cross-reacting antigen) (Nonspecific crossreacting antigen) (CD66c antigen).

CJ012_HUMAN
θ value	4.03905 (rank : 1645)	NC score	0.049415 (rank : 1369)
Query Neighborhood Hits	1959	Target Neighborhood Hits	467	Shared Neighborhood Hits	163
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

CO5A1_HUMAN
θ value	4.03905 (rank : 1646)	NC score	0.006109 (rank : 1867)
Query Neighborhood Hits	1959	Target Neighborhood Hits	434	Shared Neighborhood Hits	136
SwissProt Accessions	P20908, Q15094, Q5SUX4	Gene names	COL5A1
Domain Architecture
Description	Collagen alpha-1(V) chain precursor.

CP007_MOUSE
θ value	4.03905 (rank : 1647)	NC score	0.015682 (rank : 1707)
Query Neighborhood Hits	1959	Target Neighborhood Hits	231	Shared Neighborhood Hits	78
SwissProt Accessions	Q8C190, Q6PFD1	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf7 homolog (5-day ovary-specific transcript 1 protein).

CU087_HUMAN
θ value	4.03905 (rank : 1648)	NC score	0.013007 (rank : 1743)
Query Neighborhood Hits	1959	Target Neighborhood Hits	26	Shared Neighborhood Hits	16
SwissProt Accessions	P59051	Gene names	C21orf87
Domain Architecture	No domain graphic available
Description	Protein C21orf87.

DDX18_MOUSE
θ value	4.03905 (rank : 1649)	NC score	-0.005647 (rank : 2042)
Query Neighborhood Hits	1959	Target Neighborhood Hits	115	Shared Neighborhood Hits	20
SwissProt Accessions	Q8K363, Q3MIB0, Q8BVZ2, Q9D2E0	Gene names	Ddx18
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18).

DEN1A_MOUSE
θ value	4.03905 (rank : 1650)	NC score	0.009298 (rank : 1800)
Query Neighborhood Hits	1959	Target Neighborhood Hits	178	Shared Neighborhood Hits	78
SwissProt Accessions	Q8K382	Gene names	Dennd1a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

DNL1_HUMAN
θ value	4.03905 (rank : 1651)	NC score	0.018799 (rank : 1659)
Query Neighborhood Hits	1959	Target Neighborhood Hits	216	Shared Neighborhood Hits	81
SwissProt Accessions	P18858	Gene names	LIG1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

DPOD3_MOUSE
θ value	4.03905 (rank : 1652)	NC score	0.018027 (rank : 1667)
Query Neighborhood Hits	1959	Target Neighborhood Hits	118	Shared Neighborhood Hits	49
SwissProt Accessions	Q9EQ28	Gene names	Pold3
Domain Architecture	No domain graphic available
Description	DNA polymerase subunit delta 3 (DNA polymerase subunit delta p66).

EDA_HUMAN
θ value	4.03905 (rank : 1653)	NC score	0.002246 (rank : 1929)
Query Neighborhood Hits	1959	Target Neighborhood Hits	134	Shared Neighborhood Hits	47
SwissProt Accessions	Q92838, O75910, Q5JUM7, Q9UP77, Q9Y6L0, Q9Y6L1, Q9Y6L2, Q9Y6L3, Q9Y6L4	Gene names	EDA, ED1
Domain Architecture
Description	Ectodysplasin-A (Ectodermal dysplasia protein) (EDA protein) [Contains: Ectodysplasin-A, membrane form; Ectodysplasin-A, secreted form].

ENAH_HUMAN
θ value	4.03905 (rank : 1654)	NC score	0.045645 (rank : 1392)
Query Neighborhood Hits	1959	Target Neighborhood Hits	784	Shared Neighborhood Hits	210
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

ETV5_MOUSE
θ value	4.03905 (rank : 1655)	NC score	0.004051 (rank : 1894)
Query Neighborhood Hits	1959	Target Neighborhood Hits	328	Shared Neighborhood Hits	120
SwissProt Accessions	Q9CXC9, Q3TG49, Q8C0F3, Q9JHB1	Gene names	Etv5
Domain Architecture	No domain graphic available
Description	ETS translocation variant 5.

FBX42_HUMAN
θ value	4.03905 (rank : 1656)	NC score	0.010122 (rank : 1792)
Query Neighborhood Hits	1959	Target Neighborhood Hits	121	Shared Neighborhood Hits	41
SwissProt Accessions	Q6P3S6, Q5TEU8, Q86XI0, Q8N3N4, Q8N5F8, Q9BRM0, Q9P2L4	Gene names	FBXO42, FBX42, KIAA1332
Domain Architecture	No domain graphic available
Description	F-box only protein 42.

FOXI2_MOUSE
θ value	4.03905 (rank : 1657)	NC score	-0.004036 (rank : 2026)
Query Neighborhood Hits	1959	Target Neighborhood Hits	89	Shared Neighborhood Hits	17
SwissProt Accessions	Q3I5G5, Q8BIK9	Gene names	Foxi2
Domain Architecture	No domain graphic available
Description	Forkhead box protein I2.

GGA3_HUMAN
θ value	4.03905 (rank : 1658)	NC score	0.003849 (rank : 1900)
Query Neighborhood Hits	1959	Target Neighborhood Hits	127	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NZ52, Q15017, Q6IS16, Q9UJY3	Gene names	GGA3, KIAA0154
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

GP162_MOUSE
θ value	4.03905 (rank : 1659)	NC score	-0.005966 (rank : 2046)
Query Neighborhood Hits	1959	Target Neighborhood Hits	242	Shared Neighborhood Hits	3
SwissProt Accessions	Q3UN16, O88835	Gene names	Gpr162
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 162.

GUC2C_HUMAN
θ value	4.03905 (rank : 1660)	NC score	0.458266 (rank : 826)
Query Neighborhood Hits	1959	Target Neighborhood Hits	624	Shared Neighborhood Hits	573
SwissProt Accessions	P25092	Gene names	GUCY2C, GUC2C, STAR
Domain Architecture
Description	Heat-stable enterotoxin receptor precursor (GC-C) (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) (hSTAR).

I20RA_MOUSE
θ value	4.03905 (rank : 1661)	NC score	0.009029 (rank : 1806)
Query Neighborhood Hits	1959	Target Neighborhood Hits	37	Shared Neighborhood Hits	13
SwissProt Accessions	Q6PHB0, Q8BW64	Gene names	Il20ra
Domain Architecture	No domain graphic available
Description	Interleukin-20 receptor alpha chain precursor (IL-20R-alpha) (IL- 20R1).

IF16_HUMAN
θ value	4.03905 (rank : 1662)	NC score	0.013676 (rank : 1738)
Query Neighborhood Hits	1959	Target Neighborhood Hits	182	Shared Neighborhood Hits	85
SwissProt Accessions	Q16666, Q9UH78	Gene names	IFI16, IFNGIP1
Domain Architecture
Description	Gamma-interferon-inducible protein Ifi-16 (Interferon-inducible myeloid differentiation transcriptional activator) (IFI 16).

IF3A_HUMAN
θ value	4.03905 (rank : 1663)	NC score	0.023624 (rank : 1580)
Query Neighborhood Hits	1959	Target Neighborhood Hits	875	Shared Neighborhood Hits	112
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

IF4G1_MOUSE
θ value	4.03905 (rank : 1664)	NC score	0.031255 (rank : 1502)
Query Neighborhood Hits	1959	Target Neighborhood Hits	534	Shared Neighborhood Hits	214
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

K1024_MOUSE
θ value	4.03905 (rank : 1665)	NC score	0.003692 (rank : 1904)
Query Neighborhood Hits	1959	Target Neighborhood Hits	57	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K3V7, Q69ZS9	Gene names	Kiaa1024
Domain Architecture
Description	UPF0258 protein KIAA1024 (Protein DD1).

L2GL1_HUMAN
θ value	4.03905 (rank : 1666)	NC score	-0.000091 (rank : 1976)
Query Neighborhood Hits	1959	Target Neighborhood Hits	64	Shared Neighborhood Hits	9
SwissProt Accessions	Q15334, O00188, Q58F11, Q86UK6	Gene names	LLGL1, HUGL
Domain Architecture	No domain graphic available
Description	Lethal(2) giant larvae protein homolog 1 (LLGL) (Human homolog to the D-lgl gene) (Hugl-1) (DLG4).

LDB3_HUMAN
θ value	4.03905 (rank : 1667)	NC score	0.017951 (rank : 1668)
Query Neighborhood Hits	1959	Target Neighborhood Hits	497	Shared Neighborhood Hits	154
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

MAP4_HUMAN
θ value	4.03905 (rank : 1668)	NC score	0.056901 (rank : 1303)
Query Neighborhood Hits	1959	Target Neighborhood Hits	428	Shared Neighborhood Hits	187
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MAP4_MOUSE
θ value	4.03905 (rank : 1669)	NC score	0.056829 (rank : 1305)
Query Neighborhood Hits	1959	Target Neighborhood Hits	409	Shared Neighborhood Hits	184
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MPP2_MOUSE
θ value	4.03905 (rank : 1670)	NC score	0.023199 (rank : 1591)
Query Neighborhood Hits	1959	Target Neighborhood Hits	189	Shared Neighborhood Hits	36
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

MUCB_HUMAN
θ value	4.03905 (rank : 1671)	NC score	0.007331 (rank : 1836)
Query Neighborhood Hits	1959	Target Neighborhood Hits	233	Shared Neighborhood Hits	33
SwissProt Accessions	P04220	Gene names
Domain Architecture	No domain graphic available
Description	Ig mu heavy chain disease protein (BOT).

MUC_HUMAN
θ value	4.03905 (rank : 1672)	NC score	0.007063 (rank : 1840)
Query Neighborhood Hits	1959	Target Neighborhood Hits	231	Shared Neighborhood Hits	31
SwissProt Accessions	P01871	Gene names	IGHM
Domain Architecture
Description	Ig mu chain C region.

NBEA_HUMAN
θ value	4.03905 (rank : 1673)	NC score	-0.000075 (rank : 1974)
Query Neighborhood Hits	1959	Target Neighborhood Hits	186	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NFP9, Q9HCM8, Q9NSU1, Q9NW98, Q9Y6J1	Gene names	NBEA, BCL8B, KIAA1544, LYST2
Domain Architecture
Description	Protein neurobeachin (Lysosomal-trafficking regulator 2) (Protein BCL8B).

NCOA7_MOUSE
θ value	4.03905 (rank : 1674)	NC score	0.002696 (rank : 1922)
Query Neighborhood Hits	1959	Target Neighborhood Hits	114	Shared Neighborhood Hits	18
SwissProt Accessions	Q6DFV7, Q3TAR1, Q3UNB3, Q66K05, Q6ZQM4, Q8BJ15, Q8BJ39	Gene names	Ncoa7
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 7.

PCDH8_HUMAN
θ value	4.03905 (rank : 1675)	NC score	-0.011172 (rank : 2071)
Query Neighborhood Hits	1959	Target Neighborhood Hits	164	Shared Neighborhood Hits	14
SwissProt Accessions	O95206, Q8IYE9, Q96SF1	Gene names	PCDH8
Domain Architecture
Description	Protocadherin-8 precursor (Arcadlin).

PCQAP_HUMAN
θ value	4.03905 (rank : 1676)	NC score	0.055194 (rank : 1317)
Query Neighborhood Hits	1959	Target Neighborhood Hits	549	Shared Neighborhood Hits	178
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

PERQ1_HUMAN
θ value	4.03905 (rank : 1677)	NC score	0.006196 (rank : 1862)
Query Neighborhood Hits	1959	Target Neighborhood Hits	28	Shared Neighborhood Hits	8
SwissProt Accessions	O75420	Gene names	PERQ1
Domain Architecture
Description	PERQ amino acid rich with GYF domain protein 1.

PHXR5_MOUSE
θ value	4.03905 (rank : 1678)	NC score	0.013301 (rank : 1740)
Query Neighborhood Hits	1959	Target Neighborhood Hits	102	Shared Neighborhood Hits	12
SwissProt Accessions	P08399	Gene names	Phxr5, Per
Domain Architecture	No domain graphic available
Description	Per-hexamer repeat protein 5.

PKHA6_MOUSE
θ value	4.03905 (rank : 1679)	NC score	0.027483 (rank : 1531)
Query Neighborhood Hits	1959	Target Neighborhood Hits	591	Shared Neighborhood Hits	167
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PLCB1_HUMAN
θ value	4.03905 (rank : 1680)	NC score	0.017112 (rank : 1683)
Query Neighborhood Hits	1959	Target Neighborhood Hits	614	Shared Neighborhood Hits	105
SwissProt Accessions	Q9NQ66, O60325, Q5TFF7, Q5TGC9, Q8IV93, Q9BQW2, Q9H4H2, Q9H8H5, Q9NQ65, Q9NQH9, Q9NTH4, Q9UJP6, Q9UM26	Gene names	PLCB1, KIAA0581
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

PLRG1_HUMAN
θ value	4.03905 (rank : 1681)	NC score	-0.013442 (rank : 2077)
Query Neighborhood Hits	1959	Target Neighborhood Hits	318	Shared Neighborhood Hits	18
SwissProt Accessions	O43660, Q8WUD8	Gene names	PLRG1
Domain Architecture
Description	Pleiotropic regulator 1.

PO6F2_MOUSE
θ value	4.03905 (rank : 1682)	NC score	0.006849 (rank : 1847)
Query Neighborhood Hits	1959	Target Neighborhood Hits	639	Shared Neighborhood Hits	175
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

PZRN4_HUMAN
θ value	4.03905 (rank : 1683)	NC score	-0.004145 (rank : 2030)
Query Neighborhood Hits	1959	Target Neighborhood Hits	438	Shared Neighborhood Hits	40
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

RBNS5_HUMAN
θ value	4.03905 (rank : 1684)	NC score	0.008741 (rank : 1811)
Query Neighborhood Hits	1959	Target Neighborhood Hits	242	Shared Neighborhood Hits	69
SwissProt Accessions	Q9H1K0, Q3KP30, Q59EY8, Q8NAQ1	Gene names	ZFYVE20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20) (110 kDa protein).

RECQ4_MOUSE
θ value	4.03905 (rank : 1685)	NC score	0.001004 (rank : 1955)
Query Neighborhood Hits	1959	Target Neighborhood Hits	206	Shared Neighborhood Hits	48
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

RGL2_MOUSE
θ value	4.03905 (rank : 1686)	NC score	0.000266 (rank : 1969)
Query Neighborhood Hits	1959	Target Neighborhood Hits	51	Shared Neighborhood Hits	12
SwissProt Accessions	Q61193, Q9QUJ2	Gene names	Rgl2, Rab2l, Rlf
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator-like 2 (RalGDS-like factor) (RAS-associated protein RAB2L).

RING1_MOUSE
θ value	4.03905 (rank : 1687)	NC score	-0.007069 (rank : 2054)
Query Neighborhood Hits	1959	Target Neighborhood Hits	220	Shared Neighborhood Hits	22
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

RNPS1_HUMAN
θ value	4.03905 (rank : 1688)	NC score	0.006738 (rank : 1850)
Query Neighborhood Hits	1959	Target Neighborhood Hits	285	Shared Neighborhood Hits	56
SwissProt Accessions	Q15287, O75308, Q8WY42, Q9NYG3	Gene names	RNPS1, LDC2
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2).

RNPS1_MOUSE
θ value	4.03905 (rank : 1689)	NC score	0.006738 (rank : 1851)
Query Neighborhood Hits	1959	Target Neighborhood Hits	285	Shared Neighborhood Hits	56
SwissProt Accessions	Q99M28, Q3TMJ1, Q922H8	Gene names	Rnps1
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1.

RUSC1_HUMAN
θ value	4.03905 (rank : 1690)	NC score	0.017483 (rank : 1678)
Query Neighborhood Hits	1959	Target Neighborhood Hits	226	Shared Neighborhood Hits	71
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

SGOL2_MOUSE
θ value	4.03905 (rank : 1691)	NC score	0.004416 (rank : 1891)
Query Neighborhood Hits	1959	Target Neighborhood Hits	112	Shared Neighborhood Hits	15
SwissProt Accessions	Q7TSY8, Q811I4, Q8C9C4, Q8CGJ4, Q9CS55	Gene names	Sgol2
Domain Architecture	No domain graphic available
Description	Shugoshin-like 2.

SI1L2_MOUSE
θ value	4.03905 (rank : 1692)	NC score	0.000456 (rank : 1964)
Query Neighborhood Hits	1959	Target Neighborhood Hits	124	Shared Neighborhood Hits	20
SwissProt Accessions	Q80TE4, Q6PDY1	Gene names	Sipa1l2, Kiaa0545
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

SIGIR_MOUSE
θ value	4.03905 (rank : 1693)	NC score	0.060629 (rank : 1282)
Query Neighborhood Hits	1959	Target Neighborhood Hits	95	Shared Neighborhood Hits	61
SwissProt Accessions	Q9JLZ8, Q52L48	Gene names	Sigirr, Tir8
Domain Architecture	No domain graphic available
Description	Single Ig IL-1-related receptor (Single Ig IL-1R-related molecule) (Single immunoglobulin domain-containing IL1R-related protein) (Toll/interleukin-1 receptor 8) (TIR8).

SORC2_MOUSE
θ value	4.03905 (rank : 1694)	NC score	-0.000196 (rank : 1978)
Query Neighborhood Hits	1959	Target Neighborhood Hits	32	Shared Neighborhood Hits	9
SwissProt Accessions	Q9EPR5	Gene names	Sorcs2
Domain Architecture
Description	VPS10 domain-containing receptor SorCS2 precursor.

SORL_HUMAN
θ value	4.03905 (rank : 1695)	NC score	0.074296 (rank : 1195)
Query Neighborhood Hits	1959	Target Neighborhood Hits	440	Shared Neighborhood Hits	118
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

SYNJ2_HUMAN
θ value	4.03905 (rank : 1696)	NC score	0.015330 (rank : 1713)
Query Neighborhood Hits	1959	Target Neighborhood Hits	136	Shared Neighborhood Hits	68
SwissProt Accessions	O15056, Q5TA13, Q5TA16, Q5TA19, Q86XK0, Q8IZA8, Q9H226	Gene names	SYNJ2, KIAA0348
Domain Architecture	No domain graphic available
Description	Synaptojanin-2 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 2).

TCOF_MOUSE
θ value	4.03905 (rank : 1697)	NC score	0.056684 (rank : 1306)
Query Neighborhood Hits	1959	Target Neighborhood Hits	471	Shared Neighborhood Hits	178
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

TGON2_HUMAN
θ value	4.03905 (rank : 1698)	NC score	0.069393 (rank : 1221)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1037	Shared Neighborhood Hits	332
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TITF1_HUMAN
θ value	4.03905 (rank : 1699)	NC score	-0.009985 (rank : 2065)
Query Neighborhood Hits	1959	Target Neighborhood Hits	332	Shared Neighborhood Hits	29
SwissProt Accessions	P43699, O14954, O14955, Q9BRJ8	Gene names	TITF1, NKX2-1, NKX2A, TTF1
Domain Architecture
Description	Thyroid transcription factor 1 (Thyroid nuclear factor 1) (TTF-1) (Homeobox protein Nkx-2.1) (Homeobox protein NK-2 homolog A).

TM108_HUMAN
θ value	4.03905 (rank : 1700)	NC score	0.044258 (rank : 1404)
Query Neighborhood Hits	1959	Target Neighborhood Hits	166	Shared Neighborhood Hits	95
SwissProt Accessions	Q6UXF1, Q9BQH1, Q9BW81, Q9C0H3	Gene names	TMEM108, KIAA1690
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

TREF1_MOUSE
θ value	4.03905 (rank : 1701)	NC score	-0.001852 (rank : 2001)
Query Neighborhood Hits	1959	Target Neighborhood Hits	682	Shared Neighborhood Hits	99
SwissProt Accessions	Q8BXJ2, Q6PCQ4, Q80X25, Q810H8, Q8BY31	Gene names	Trerf1
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132).

YAP1_HUMAN
θ value	4.03905 (rank : 1702)	NC score	0.013977 (rank : 1732)
Query Neighborhood Hits	1959	Target Neighborhood Hits	173	Shared Neighborhood Hits	69
SwissProt Accessions	P46937	Gene names	YAP1, YAP65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

ZCC2_HUMAN
θ value	4.03905 (rank : 1703)	NC score	0.003851 (rank : 1899)
Query Neighborhood Hits	1959	Target Neighborhood Hits	47	Shared Neighborhood Hits	14
SwissProt Accessions	Q7Z2W4, Q8IW57, Q8TAJ3, Q96N79, Q9H8R9, Q9P0Y7	Gene names	ZC3HAV1, ZC3HDC2
Domain Architecture
Description	Zinc finger CCCH type antiviral protein 1 (Zinc finger CCCH domain- containing protein 2).

ZN598_HUMAN
θ value	4.03905 (rank : 1704)	NC score	0.019107 (rank : 1652)
Query Neighborhood Hits	1959	Target Neighborhood Hits	339	Shared Neighborhood Hits	89
SwissProt Accessions	Q86UK7, Q8IW49, Q8N3D9, Q96FG3, Q9H7J3	Gene names	ZNF598
Domain Architecture	No domain graphic available
Description	Zinc finger protein 598.

ZN688_HUMAN
θ value	4.03905 (rank : 1705)	NC score	-0.024604 (rank : 2102)
Query Neighborhood Hits	1959	Target Neighborhood Hits	873	Shared Neighborhood Hits	127
SwissProt Accessions	Q8WV14, O75701, Q8IW91, Q96MN0	Gene names	ZNF688
Domain Architecture	No domain graphic available
Description	Zinc finger protein 688.

ZO3_MOUSE
θ value	4.03905 (rank : 1706)	NC score	0.007019 (rank : 1841)
Query Neighborhood Hits	1959	Target Neighborhood Hits	224	Shared Neighborhood Hits	47
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

2DMB_MOUSE
θ value	5.27518 (rank : 1707)	NC score	-0.009097 (rank : 2061)
Query Neighborhood Hits	1959	Target Neighborhood Hits	214	Shared Neighborhood Hits	17
SwissProt Accessions	P35737	Gene names	H2-DMb1, H-2Mb1, Mb
Domain Architecture
Description	Class II histocompatibility antigen, M beta 1 chain precursor (H2-M beta 1 chain).

3BP2_MOUSE
θ value	5.27518 (rank : 1708)	NC score	0.023639 (rank : 1579)
Query Neighborhood Hits	1959	Target Neighborhood Hits	142	Shared Neighborhood Hits	57
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

41_MOUSE
θ value	5.27518 (rank : 1709)	NC score	-0.004774 (rank : 2037)
Query Neighborhood Hits	1959	Target Neighborhood Hits	184	Shared Neighborhood Hits	34
SwissProt Accessions	P48193, Q68FF1, Q6NVF5	Gene names	Epb41, Epb4.1
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (4.1R).

ALLC_HUMAN
θ value	5.27518 (rank : 1710)	NC score	0.003003 (rank : 1918)
Query Neighborhood Hits	1959	Target Neighborhood Hits	3	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N6M5, Q53T95, Q5RL81, Q96RE6, Q9NZA7	Gene names	ALLC
Domain Architecture	No domain graphic available
Description	Probable allantoicase (EC 3.5.3.4) (Allantoate amidinohydrolase).

ALMS1_HUMAN
θ value	5.27518 (rank : 1711)	NC score	0.028132 (rank : 1525)
Query Neighborhood Hits	1959	Target Neighborhood Hits	356	Shared Neighborhood Hits	127
SwissProt Accessions	Q8TCU4, Q53S05, Q580Q8, Q86VP9, Q9Y4G4	Gene names	ALMS1, KIAA0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1.

ALX3_MOUSE
θ value	5.27518 (rank : 1712)	NC score	-0.013762 (rank : 2080)
Query Neighborhood Hits	1959	Target Neighborhood Hits	386	Shared Neighborhood Hits	42
SwissProt Accessions	O70137	Gene names	Alx3
Domain Architecture
Description	Homeobox protein aristaless-like 3 (Proline-rich transcription factor ALX3).

ANKS6_MOUSE
θ value	5.27518 (rank : 1713)	NC score	0.010763 (rank : 1781)
Query Neighborhood Hits	1959	Target Neighborhood Hits	435	Shared Neighborhood Hits	81
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

ANR11_HUMAN
θ value	5.27518 (rank : 1714)	NC score	0.025026 (rank : 1564)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1289	Shared Neighborhood Hits	294
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

ATF2_HUMAN
θ value	5.27518 (rank : 1715)	NC score	0.012796 (rank : 1746)
Query Neighborhood Hits	1959	Target Neighborhood Hits	402	Shared Neighborhood Hits	104
SwissProt Accessions	P15336, Q13000	Gene names	ATF2, CREB2, CREBP1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (HB16).

ATF2_MOUSE
θ value	5.27518 (rank : 1716)	NC score	0.012082 (rank : 1760)
Query Neighborhood Hits	1959	Target Neighborhood Hits	397	Shared Neighborhood Hits	103
SwissProt Accessions	P16951, Q64089, Q64090, Q64091	Gene names	Atf2
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (MXBP protein).

B3A3_MOUSE
θ value	5.27518 (rank : 1717)	NC score	0.001449 (rank : 1944)
Query Neighborhood Hits	1959	Target Neighborhood Hits	112	Shared Neighborhood Hits	39
SwissProt Accessions	P16283	Gene names	Slc4a3, Ae3
Domain Architecture
Description	Anion exchange protein 3 (Neuronal band 3-like protein) (Solute carrier family 4 member 3).

BAI1_HUMAN
θ value	5.27518 (rank : 1718)	NC score	0.012628 (rank : 1750)
Query Neighborhood Hits	1959	Target Neighborhood Hits	375	Shared Neighborhood Hits	122
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI2_MOUSE
θ value	5.27518 (rank : 1719)	NC score	0.006476 (rank : 1853)
Query Neighborhood Hits	1959	Target Neighborhood Hits	323	Shared Neighborhood Hits	66
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAT3_HUMAN
θ value	5.27518 (rank : 1720)	NC score	0.032237 (rank : 1497)
Query Neighborhood Hits	1959	Target Neighborhood Hits	490	Shared Neighborhood Hits	193
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

BAZ1A_HUMAN
θ value	5.27518 (rank : 1721)	NC score	0.016909 (rank : 1690)
Query Neighborhood Hits	1959	Target Neighborhood Hits	693	Shared Neighborhood Hits	127
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

BMP6_HUMAN
θ value	5.27518 (rank : 1722)	NC score	-0.007555 (rank : 2055)
Query Neighborhood Hits	1959	Target Neighborhood Hits	82	Shared Neighborhood Hits	4
SwissProt Accessions	P22004	Gene names	BMP6, VGR
Domain Architecture
Description	Bone morphogenetic protein 6 precursor (BMP-6).

CALR_MOUSE
θ value	5.27518 (rank : 1723)	NC score	0.001894 (rank : 1937)
Query Neighborhood Hits	1959	Target Neighborhood Hits	68	Shared Neighborhood Hits	12
SwissProt Accessions	P14211	Gene names	Calr
Domain Architecture
Description	Calreticulin precursor (CRP55) (Calregulin) (HACBP) (ERp60).

CECR2_HUMAN
θ value	5.27518 (rank : 1724)	NC score	0.024960 (rank : 1565)
Query Neighborhood Hits	1959	Target Neighborhood Hits	543	Shared Neighborhood Hits	192
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

CN155_HUMAN
θ value	5.27518 (rank : 1725)	NC score	0.067423 (rank : 1235)
Query Neighborhood Hits	1959	Target Neighborhood Hits	385	Shared Neighborhood Hits	181
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

CO1A1_MOUSE
θ value	5.27518 (rank : 1726)	NC score	0.011787 (rank : 1764)
Query Neighborhood Hits	1959	Target Neighborhood Hits	457	Shared Neighborhood Hits	142
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CS021_HUMAN
θ value	5.27518 (rank : 1727)	NC score	0.016578 (rank : 1695)
Query Neighborhood Hits	1959	Target Neighborhood Hits	98	Shared Neighborhood Hits	52
SwissProt Accessions	Q8IVT2	Gene names	C19orf21
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf21.

CUTL1_HUMAN
θ value	5.27518 (rank : 1728)	NC score	0.019639 (rank : 1646)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1574	Shared Neighborhood Hits	269
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

DDX20_MOUSE
θ value	5.27518 (rank : 1729)	NC score	-0.005796 (rank : 2043)
Query Neighborhood Hits	1959	Target Neighborhood Hits	177	Shared Neighborhood Hits	47
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

DDX46_MOUSE
θ value	5.27518 (rank : 1730)	NC score	-0.001613 (rank : 1998)
Query Neighborhood Hits	1959	Target Neighborhood Hits	358	Shared Neighborhood Hits	63
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

DNMBP_MOUSE
θ value	5.27518 (rank : 1731)	NC score	0.029668 (rank : 1511)
Query Neighborhood Hits	1959	Target Neighborhood Hits	435	Shared Neighborhood Hits	116
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

DOK7_MOUSE
θ value	5.27518 (rank : 1732)	NC score	0.012572 (rank : 1751)
Query Neighborhood Hits	1959	Target Neighborhood Hits	169	Shared Neighborhood Hits	76
SwissProt Accessions	Q18PE0, Q3TCZ6, Q5FW70, Q8C8U7	Gene names	Dok7
Domain Architecture	No domain graphic available
Description	Protein Dok-7 (Downstream of tyrosine kinase 7).

DUS8_MOUSE
θ value	5.27518 (rank : 1733)	NC score	0.001312 (rank : 1948)
Query Neighborhood Hits	1959	Target Neighborhood Hits	119	Shared Neighborhood Hits	33
SwissProt Accessions	O09112	Gene names	Dusp8, Nttp1
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Neuronal tyrosine threonine phosphatase 1).

DYN3_HUMAN
θ value	5.27518 (rank : 1734)	NC score	0.008964 (rank : 1808)
Query Neighborhood Hits	1959	Target Neighborhood Hits	158	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UQ16, O14982, O95555, Q5W129, Q9H0P3, Q9H548, Q9NQ68, Q9NQN6	Gene names	DNM3, KIAA0820
Domain Architecture
Description	Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin).

EGR2_MOUSE
θ value	5.27518 (rank : 1735)	NC score	-0.025008 (rank : 2104)
Query Neighborhood Hits	1959	Target Neighborhood Hits	745	Shared Neighborhood Hits	71
SwissProt Accessions	P08152	Gene names	Egr2, Egr-2, Krox-20, Zfp-25
Domain Architecture	No domain graphic available
Description	Early growth response protein 2 (EGR-2) (Krox-20 protein).

EP400_HUMAN
θ value	5.27518 (rank : 1736)	NC score	0.019293 (rank : 1649)
Query Neighborhood Hits	1959	Target Neighborhood Hits	556	Shared Neighborhood Hits	213
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

EVI1_MOUSE
θ value	5.27518 (rank : 1737)	NC score	-0.026842 (rank : 2111)
Query Neighborhood Hits	1959	Target Neighborhood Hits	826	Shared Neighborhood Hits	70
SwissProt Accessions	P14404	Gene names	Evi1, Evi-1
Domain Architecture	No domain graphic available
Description	Ecotropic virus integration 1 site protein.

EVL_HUMAN
θ value	5.27518 (rank : 1738)	NC score	0.025427 (rank : 1558)
Query Neighborhood Hits	1959	Target Neighborhood Hits	260	Shared Neighborhood Hits	129
SwissProt Accessions	Q9UI08, O95884, Q7Z522, Q8TBV1, Q9UF25, Q9UIC2	Gene names	EVL, RNB6
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

FMNL_HUMAN
θ value	5.27518 (rank : 1739)	NC score	0.033659 (rank : 1484)
Query Neighborhood Hits	1959	Target Neighborhood Hits	529	Shared Neighborhood Hits	192
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

GPTC8_HUMAN
θ value	5.27518 (rank : 1740)	NC score	0.023699 (rank : 1578)
Query Neighborhood Hits	1959	Target Neighborhood Hits	366	Shared Neighborhood Hits	105
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

H14_HUMAN
θ value	5.27518 (rank : 1741)	NC score	0.011108 (rank : 1774)
Query Neighborhood Hits	1959	Target Neighborhood Hits	87	Shared Neighborhood Hits	36
SwissProt Accessions	P10412	Gene names	HIST1H1E, H1F4
Domain Architecture
Description	Histone H1.4 (Histone H1b).

HCFC1_HUMAN
θ value	5.27518 (rank : 1742)	NC score	0.048712 (rank : 1373)
Query Neighborhood Hits	1959	Target Neighborhood Hits	331	Shared Neighborhood Hits	143
SwissProt Accessions	P51610, Q6P4G5	Gene names	HCFC1, HCF1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) (VP16 accessory protein) (VCAF) (CFF) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C- terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

HCLS1_HUMAN
θ value	5.27518 (rank : 1743)	NC score	0.026921 (rank : 1534)
Query Neighborhood Hits	1959	Target Neighborhood Hits	358	Shared Neighborhood Hits	132
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

HCN4_HUMAN
θ value	5.27518 (rank : 1744)	NC score	0.018841 (rank : 1656)
Query Neighborhood Hits	1959	Target Neighborhood Hits	303	Shared Neighborhood Hits	132
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

HD_MOUSE
θ value	5.27518 (rank : 1745)	NC score	0.007174 (rank : 1839)
Query Neighborhood Hits	1959	Target Neighborhood Hits	116	Shared Neighborhood Hits	43
SwissProt Accessions	P42859	Gene names	Hd, Hdh
Domain Architecture
Description	Huntingtin (Huntington disease protein homolog) (HD protein).

HSPB8_HUMAN
θ value	5.27518 (rank : 1746)	NC score	0.000089 (rank : 1971)
Query Neighborhood Hits	1959	Target Neighborhood Hits	25	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UJY1, Q6FIH3, Q9UKS3	Gene names	HSPB8, CRYAC, E2IG1, HSP22
Domain Architecture
Description	Heat-shock protein beta-8 (HspB8) (Alpha crystallin C chain) (Small stress protein-like protein HSP22) (E2-induced gene 1 protein) (Protein kinase H11).

I11RA_HUMAN
θ value	5.27518 (rank : 1747)	NC score	0.046059 (rank : 1390)
Query Neighborhood Hits	1959	Target Neighborhood Hits	138	Shared Neighborhood Hits	63
SwissProt Accessions	Q14626, Q16542, Q7KYJ7	Gene names	IL11RA
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha chain precursor (IL-11R-alpha) (IL- 11RA).

ILDR1_MOUSE
θ value	5.27518 (rank : 1748)	NC score	0.002135 (rank : 1931)
Query Neighborhood Hits	1959	Target Neighborhood Hits	33	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CBR1, Q6PFB3, Q8CB39, Q91VS0	Gene names	Ildr1
Domain Architecture	No domain graphic available
Description	Immunoglobulin-like domain-containing receptor 1 precursor.

IRAK2_HUMAN
θ value	5.27518 (rank : 1749)	NC score	0.624587 (rank : 763)
Query Neighborhood Hits	1959	Target Neighborhood Hits	714	Shared Neighborhood Hits	689
SwissProt Accessions	O43187	Gene names	IRAK2
Domain Architecture
Description	Interleukin-1 receptor-associated kinase-like 2 (IRAK-2).

JPH3_MOUSE
θ value	5.27518 (rank : 1750)	NC score	0.008263 (rank : 1819)
Query Neighborhood Hits	1959	Target Neighborhood Hits	80	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ET77, Q9EQZ2	Gene names	Jph3, Jp3
Domain Architecture
Description	Junctophilin-3 (Junctophilin type 3) (JP-3).

K1849_MOUSE
θ value	5.27518 (rank : 1751)	NC score	0.004627 (rank : 1890)
Query Neighborhood Hits	1959	Target Neighborhood Hits	335	Shared Neighborhood Hits	82
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

K1949_MOUSE
θ value	5.27518 (rank : 1752)	NC score	0.021516 (rank : 1617)
Query Neighborhood Hits	1959	Target Neighborhood Hits	134	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BQ30, Q3UDS6, Q8CEY9, Q8R3D8	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA1949 homolog.

KCNQ4_HUMAN
θ value	5.27518 (rank : 1753)	NC score	0.001927 (rank : 1935)
Query Neighborhood Hits	1959	Target Neighborhood Hits	136	Shared Neighborhood Hits	28
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

LAP4_HUMAN
θ value	5.27518 (rank : 1754)	NC score	0.018712 (rank : 1660)
Query Neighborhood Hits	1959	Target Neighborhood Hits	608	Shared Neighborhood Hits	129
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

LIPA3_MOUSE
θ value	5.27518 (rank : 1755)	NC score	0.010753 (rank : 1782)
Query Neighborhood Hits	1959	Target Neighborhood Hits	636	Shared Neighborhood Hits	76
SwissProt Accessions	P60469	Gene names	Ppfia3
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

LMBL3_HUMAN
θ value	5.27518 (rank : 1756)	NC score	0.001622 (rank : 1940)
Query Neighborhood Hits	1959	Target Neighborhood Hits	88	Shared Neighborhood Hits	25
SwissProt Accessions	Q96JM7, Q5VUM9, Q6P9B5	Gene names	L3MBTL3, KIAA1798
Domain Architecture	No domain graphic available
Description	Lethal(3)malignant brain tumor-like 3 protein (L(3)mbt-like 3 protein) (H-l(3)mbt-like protein).

LNP_MOUSE
θ value	5.27518 (rank : 1757)	NC score	0.009953 (rank : 1794)
Query Neighborhood Hits	1959	Target Neighborhood Hits	83	Shared Neighborhood Hits	41
SwissProt Accessions	Q7TQ95, Q69ZC5, Q6PAQ1, Q6PEN8	Gene names	Lnp, Kiaa1715, Uln
Domain Architecture	No domain graphic available
Description	Protein lunapark (Protein ulnaless).

MAML2_HUMAN
θ value	5.27518 (rank : 1758)	NC score	0.020389 (rank : 1640)
Query Neighborhood Hits	1959	Target Neighborhood Hits	360	Shared Neighborhood Hits	98
SwissProt Accessions	Q8IZL2, Q6AI23, Q6Y3A3, Q8IUL3, Q96JK6	Gene names	MAML2, KIAA1819
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 2 (Mam-2).

MEFV_MOUSE
θ value	5.27518 (rank : 1759)	NC score	-0.001129 (rank : 1994)
Query Neighborhood Hits	1959	Target Neighborhood Hits	236	Shared Neighborhood Hits	40
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

MEGF9_MOUSE
θ value	5.27518 (rank : 1760)	NC score	0.035254 (rank : 1472)
Query Neighborhood Hits	1959	Target Neighborhood Hits	896	Shared Neighborhood Hits	292
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MELPH_HUMAN
θ value	5.27518 (rank : 1761)	NC score	0.008348 (rank : 1817)
Query Neighborhood Hits	1959	Target Neighborhood Hits	145	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BV36, Q9HA71	Gene names	MLPH, SLAC2A
Domain Architecture	No domain graphic available
Description	Melanophilin (Exophilin-3) (Synaptotagmin-like protein 2a) (Slp homolog lacking C2 domains a).

MEN1_HUMAN
θ value	5.27518 (rank : 1762)	NC score	0.005124 (rank : 1884)
Query Neighborhood Hits	1959	Target Neighborhood Hits	21	Shared Neighborhood Hits	12
SwissProt Accessions	O00255, O00632, Q9BUK2	Gene names	MEN1, SCG2
Domain Architecture
Description	Menin.

MFAP3_MOUSE
θ value	5.27518 (rank : 1763)	NC score	0.070172 (rank : 1214)
Query Neighborhood Hits	1959	Target Neighborhood Hits	97	Shared Neighborhood Hits	86
SwissProt Accessions	Q922T2, Q8BHK5	Gene names	Mfap3
Domain Architecture	No domain graphic available
Description	Microfibril-associated glycoprotein 3 precursor.

MNT_MOUSE
θ value	5.27518 (rank : 1764)	NC score	0.033383 (rank : 1487)
Query Neighborhood Hits	1959	Target Neighborhood Hits	432	Shared Neighborhood Hits	150
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

NASP_HUMAN
θ value	5.27518 (rank : 1765)	NC score	0.015567 (rank : 1710)
Query Neighborhood Hits	1959	Target Neighborhood Hits	709	Shared Neighborhood Hits	125
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

NCTR2_HUMAN
θ value	5.27518 (rank : 1766)	NC score	0.015561 (rank : 1711)
Query Neighborhood Hits	1959	Target Neighborhood Hits	99	Shared Neighborhood Hits	50
SwissProt Accessions	O95944, Q9H562, Q9H563, Q9H564, Q9UMT1, Q9UMT2	Gene names	NCR2, LY95
Domain Architecture
Description	Natural cytotoxicity triggering receptor 2 precursor (Natural killer cell p44-related protein) (NKp44) (NK-p44) (NK cell-activating receptor) (Lymphocyte antigen 95 homolog) (CD336 antigen).

NDC1_MOUSE
θ value	5.27518 (rank : 1767)	NC score	0.004018 (rank : 1895)
Query Neighborhood Hits	1959	Target Neighborhood Hits	45	Shared Neighborhood Hits	17
SwissProt Accessions	Q8VCB1	Gene names	Tmem48, Ndc1
Domain Architecture	No domain graphic available
Description	Nucleoporin NDC1 (Transmembrane protein 48).

NETR_MOUSE
θ value	5.27518 (rank : 1768)	NC score	-0.014331 (rank : 2083)
Query Neighborhood Hits	1959	Target Neighborhood Hits	216	Shared Neighborhood Hits	14
SwissProt Accessions	O08762	Gene names	Prss12, Bssp3
Domain Architecture
Description	Neurotrypsin precursor (EC 3.4.21.-) (Motopsin) (Brain-specific serine protease 3) (BSSP-3).

OBF1_MOUSE
θ value	5.27518 (rank : 1769)	NC score	0.017445 (rank : 1680)
Query Neighborhood Hits	1959	Target Neighborhood Hits	73	Shared Neighborhood Hits	40
SwissProt Accessions	Q64693	Gene names	Pou2af1, Obf-1
Domain Architecture	No domain graphic available
Description	POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (OCT-binding factor 1) (BOB-1) (BOB1) (OCA-B).

PCBP4_HUMAN
θ value	5.27518 (rank : 1770)	NC score	0.001904 (rank : 1936)
Query Neighborhood Hits	1959	Target Neighborhood Hits	49	Shared Neighborhood Hits	16
SwissProt Accessions	P57723, Q96AH7	Gene names	PCBP4
Domain Architecture
Description	Poly(rC)-binding protein 4 (Alpha-CP4).

PGFRL_HUMAN
θ value	5.27518 (rank : 1771)	NC score	0.151958 (rank : 1054)
Query Neighborhood Hits	1959	Target Neighborhood Hits	115	Shared Neighborhood Hits	111
SwissProt Accessions	Q15198, Q6FH04	Gene names	PDGFRL, PRLTS
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor receptor-like protein precursor (PDGF receptor beta-like tumor suppressor).

PHLPP_MOUSE
θ value	5.27518 (rank : 1772)	NC score	0.021123 (rank : 1624)
Query Neighborhood Hits	1959	Target Neighborhood Hits	394	Shared Neighborhood Hits	93
SwissProt Accessions	Q8CHE4, Q6PCN0, Q8QZU8, Q8R5E5, Q99KL6	Gene names	Phlpp, Kiaa0606, Plekhe1, Scop
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein).

PO6F2_HUMAN
θ value	5.27518 (rank : 1773)	NC score	0.006179 (rank : 1863)
Query Neighborhood Hits	1959	Target Neighborhood Hits	618	Shared Neighborhood Hits	159
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

PSG10_HUMAN
θ value	5.27518 (rank : 1774)	NC score	0.156017 (rank : 1047)
Query Neighborhood Hits	1959	Target Neighborhood Hits	227	Shared Neighborhood Hits	186
SwissProt Accessions	Q15235, O75244, Q15224	Gene names	PSG10, PSG12
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 10 precursor (PSBG-10) (PSBG- 12).

PZRN3_HUMAN
θ value	5.27518 (rank : 1775)	NC score	-0.003896 (rank : 2025)
Query Neighborhood Hits	1959	Target Neighborhood Hits	461	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

RAVR1_MOUSE
θ value	5.27518 (rank : 1776)	NC score	-0.002789 (rank : 2014)
Query Neighborhood Hits	1959	Target Neighborhood Hits	179	Shared Neighborhood Hits	28
SwissProt Accessions	Q9CW46, Q5DTT6, Q811K0, Q8C3Z1, Q8CA14	Gene names	Raver1, Kiaa1978
Domain Architecture	No domain graphic available
Description	Ribonucleoprotein PTB-binding 1 (Protein raver-1).

REEP2_MOUSE
θ value	5.27518 (rank : 1777)	NC score	-0.000887 (rank : 1987)
Query Neighborhood Hits	1959	Target Neighborhood Hits	31	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VCD6	Gene names	Reep2
Domain Architecture	No domain graphic available
Description	Receptor expression-enhancing protein 2.

RFX1_MOUSE
θ value	5.27518 (rank : 1778)	NC score	0.015582 (rank : 1709)
Query Neighborhood Hits	1959	Target Neighborhood Hits	181	Shared Neighborhood Hits	93
SwissProt Accessions	P48377	Gene names	Rfx1
Domain Architecture
Description	DNA-binding protein RFX1.

SAFB1_HUMAN
θ value	5.27518 (rank : 1779)	NC score	0.009552 (rank : 1798)
Query Neighborhood Hits	1959	Target Neighborhood Hits	493	Shared Neighborhood Hits	88
SwissProt Accessions	Q15424, O60406, Q59HH8	Gene names	SAFB, HAP, HET, SAFB1
Domain Architecture
Description	Scaffold attachment factor B (Scaffold attachment factor B1) (SAF-B) (HSP27 estrogen response element-TATA box-binding protein) (HSP27 ERE- TATA-binding protein).

SAM14_HUMAN
θ value	5.27518 (rank : 1780)	NC score	0.007701 (rank : 1829)
Query Neighborhood Hits	1959	Target Neighborhood Hits	81	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IZD0, Q8N2X0	Gene names	SAMD14
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 14.

SDC3_MOUSE
θ value	5.27518 (rank : 1781)	NC score	0.032021 (rank : 1499)
Query Neighborhood Hits	1959	Target Neighborhood Hits	107	Shared Neighborhood Hits	60
SwissProt Accessions	Q64519, Q3UDD9, Q6ZQA4, Q7TQD4	Gene names	Sdc3, Kiaa0468
Domain Architecture
Description	Syndecan-3 precursor (SYND3).

SEM6D_MOUSE
θ value	5.27518 (rank : 1782)	NC score	0.000332 (rank : 1966)
Query Neighborhood Hits	1959	Target Neighborhood Hits	161	Shared Neighborhood Hits	51
SwissProt Accessions	Q76KF0, Q76KF1, Q76KF2, Q76KF3, Q76KF4, Q80TD0	Gene names	Sema6d, Kiaa1479
Domain Architecture	No domain graphic available
Description	Semaphorin-6D precursor.

SOX30_MOUSE
θ value	5.27518 (rank : 1783)	NC score	0.007621 (rank : 1831)
Query Neighborhood Hits	1959	Target Neighborhood Hits	374	Shared Neighborhood Hits	137
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

SOX9_HUMAN
θ value	5.27518 (rank : 1784)	NC score	0.003204 (rank : 1914)
Query Neighborhood Hits	1959	Target Neighborhood Hits	210	Shared Neighborhood Hits	75
SwissProt Accessions	P48436	Gene names	SOX9
Domain Architecture
Description	Transcription factor SOX-9.

SSBP4_HUMAN
θ value	5.27518 (rank : 1785)	NC score	0.029424 (rank : 1515)
Query Neighborhood Hits	1959	Target Neighborhood Hits	753	Shared Neighborhood Hits	267
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

STK31_MOUSE
θ value	5.27518 (rank : 1786)	NC score	0.289649 (rank : 954)
Query Neighborhood Hits	1959	Target Neighborhood Hits	474	Shared Neighborhood Hits	309
SwissProt Accessions	Q99MW1	Gene names	Stk31
Domain Architecture
Description	Serine/threonine-protein kinase 31 (EC 2.7.11.1).

TF3B_HUMAN
θ value	5.27518 (rank : 1787)	NC score	0.004785 (rank : 1887)
Query Neighborhood Hits	1959	Target Neighborhood Hits	60	Shared Neighborhood Hits	20
SwissProt Accessions	Q92994, Q13223, Q5PR24, Q6IQ02, Q9HCW6, Q9HCW7, Q9HCW8	Gene names	BRF1, BRF
Domain Architecture
Description	Transcription factor IIIB 90 kDa subunit (TFIIIB90) (hTFIIIB90) (B- related factor 1) (BRF-1) (hBRF) (TATA box-binding protein-associated factor, RNA polymerase III, subunit 2) (TAF3B2).

TM16H_MOUSE
θ value	5.27518 (rank : 1788)	NC score	0.006374 (rank : 1858)
Query Neighborhood Hits	1959	Target Neighborhood Hits	65	Shared Neighborhood Hits	18
SwissProt Accessions	Q6PB70, Q69ZE4	Gene names	Tmem16h, Kiaa1623
Domain Architecture	No domain graphic available
Description	Transmembrane protein 16H.

UBP51_HUMAN
θ value	5.27518 (rank : 1789)	NC score	-0.001014 (rank : 1991)
Query Neighborhood Hits	1959	Target Neighborhood Hits	162	Shared Neighborhood Hits	56
SwissProt Accessions	Q70EK9, Q8IWJ8	Gene names	USP51
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51).

VGLL1_HUMAN
θ value	5.27518 (rank : 1790)	NC score	0.011606 (rank : 1766)
Query Neighborhood Hits	1959	Target Neighborhood Hits	12	Shared Neighborhood Hits	7
SwissProt Accessions	Q99990	Gene names	VGLL1, TDU
Domain Architecture	No domain graphic available
Description	Transcription cofactor vestigial-like protein 1 (Vgl-1) (Protein TONDU).

ZN524_HUMAN
θ value	5.27518 (rank : 1791)	NC score	-0.027452 (rank : 2115)
Query Neighborhood Hits	1959	Target Neighborhood Hits	707	Shared Neighborhood Hits	45
SwissProt Accessions	Q96C55, Q6NW31, Q96IL7	Gene names	ZNF524
Domain Architecture	No domain graphic available
Description	Zinc finger protein 524.

ZN628_HUMAN
θ value	5.27518 (rank : 1792)	NC score	-0.026606 (rank : 2110)
Query Neighborhood Hits	1959	Target Neighborhood Hits	814	Shared Neighborhood Hits	80
SwissProt Accessions	Q5EBL2, Q86X34	Gene names	ZNF628
Domain Architecture	No domain graphic available
Description	Zinc finger protein 628.

ZO1_HUMAN
θ value	5.27518 (rank : 1793)	NC score	0.018127 (rank : 1666)
Query Neighborhood Hits	1959	Target Neighborhood Hits	474	Shared Neighborhood Hits	163
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ZYX_MOUSE
θ value	5.27518 (rank : 1794)	NC score	0.017030 (rank : 1686)
Query Neighborhood Hits	1959	Target Neighborhood Hits	347	Shared Neighborhood Hits	114
SwissProt Accessions	Q62523, P70461	Gene names	Zyx
Domain Architecture
Description	Zyxin.

ASB2_MOUSE
θ value	6.88961 (rank : 1795)	NC score	0.004740 (rank : 1888)
Query Neighborhood Hits	1959	Target Neighborhood Hits	321	Shared Neighborhood Hits	37
SwissProt Accessions	Q8K0L0, Q9CTH4, Q9WV73	Gene names	Asb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ATX2L_HUMAN
θ value	6.88961 (rank : 1796)	NC score	0.038704 (rank : 1453)
Query Neighborhood Hits	1959	Target Neighborhood Hits	443	Shared Neighborhood Hits	199
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

CAN12_MOUSE
θ value	6.88961 (rank : 1797)	NC score	-0.002312 (rank : 2005)
Query Neighborhood Hits	1959	Target Neighborhood Hits	56	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ER56, Q9ER53, Q9ER54, Q9ER55	Gene names	Capn12
Domain Architecture
Description	Calpain-12 (EC 3.4.22.-).

CD44_MOUSE
θ value	6.88961 (rank : 1798)	NC score	0.003258 (rank : 1911)
Query Neighborhood Hits	1959	Target Neighborhood Hits	64	Shared Neighborhood Hits	17
SwissProt Accessions	P15379, Q05732, Q61395, Q62060, Q62061, Q62062, Q62063, Q62408, Q62409, Q64296, Q99J14, Q9QYX8	Gene names	Cd44, Ly-24
Domain Architecture
Description	CD44 antigen precursor (Phagocytic glycoprotein 1) (PGP-1) (HUTCH-I) (Extracellular matrix receptor III) (ECMR-III) (GP90 lymphocyte homing/adhesion receptor) (Hermes antigen) (Hyaluronate receptor) (Lymphocyte antigen Ly-24).

CD6_HUMAN
θ value	6.88961 (rank : 1799)	NC score	-0.002405 (rank : 2008)
Query Neighborhood Hits	1959	Target Neighborhood Hits	65	Shared Neighborhood Hits	13
SwissProt Accessions	P30203, Q9UMF2, Q9Y4K7, Q9Y4K8, Q9Y4K9, Q9Y4L0	Gene names	CD6
Domain Architecture
Description	T-cell differentiation antigen CD6 precursor (T12) (TP120).

CELR3_HUMAN
θ value	6.88961 (rank : 1800)	NC score	-0.011198 (rank : 2072)
Query Neighborhood Hits	1959	Target Neighborhood Hits	680	Shared Neighborhood Hits	83
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

CITE4_MOUSE
θ value	6.88961 (rank : 1801)	NC score	0.011026 (rank : 1775)
Query Neighborhood Hits	1959	Target Neighborhood Hits	73	Shared Neighborhood Hits	35
SwissProt Accessions	Q9WUL8, Q66JX0, Q8R176, Q9CZV4	Gene names	Cited4, Mrg2
Domain Architecture	No domain graphic available
Description	Cbp/p300-interacting transactivator 4 (MSG1-related protein 2) (MRG- 2).

CLGN_MOUSE
θ value	6.88961 (rank : 1802)	NC score	0.006858 (rank : 1846)
Query Neighborhood Hits	1959	Target Neighborhood Hits	142	Shared Neighborhood Hits	33
SwissProt Accessions	P52194, Q9D2K5	Gene names	Clgn, Meg1
Domain Architecture
Description	Calmegin precursor (MEG 1 antigen) (Calnexin-T) (A2/6).

CO3A1_HUMAN
θ value	6.88961 (rank : 1803)	NC score	0.013199 (rank : 1742)
Query Neighborhood Hits	1959	Target Neighborhood Hits	452	Shared Neighborhood Hits	152
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CO5A1_MOUSE
θ value	6.88961 (rank : 1804)	NC score	0.006367 (rank : 1859)
Query Neighborhood Hits	1959	Target Neighborhood Hits	419	Shared Neighborhood Hits	137
SwissProt Accessions	O88207	Gene names	Col5a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(V) chain precursor.

CRSP2_HUMAN
θ value	6.88961 (rank : 1805)	NC score	0.033272 (rank : 1490)
Query Neighborhood Hits	1959	Target Neighborhood Hits	380	Shared Neighborhood Hits	167
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

CSPG3_HUMAN
θ value	6.88961 (rank : 1806)	NC score	0.002534 (rank : 1927)
Query Neighborhood Hits	1959	Target Neighborhood Hits	676	Shared Neighborhood Hits	151
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

DAB2P_HUMAN
θ value	6.88961 (rank : 1807)	NC score	0.006492 (rank : 1852)
Query Neighborhood Hits	1959	Target Neighborhood Hits	303	Shared Neighborhood Hits	64
SwissProt Accessions	Q5VWQ8, Q8TDL2, Q96SE1, Q9C0C0	Gene names	DAB2IP, AF9Q34, AIP1, KIAA1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein) (DAB2 interaction protein) (ASK-interacting protein 1).

DAB2P_MOUSE
θ value	6.88961 (rank : 1808)	NC score	0.005611 (rank : 1878)
Query Neighborhood Hits	1959	Target Neighborhood Hits	284	Shared Neighborhood Hits	54
SwissProt Accessions	Q3UHC7, Q3TPD5, Q3UH44, Q6JTV1, Q80T97	Gene names	Dab2ip, Kiaa1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein).

DAB2_HUMAN
θ value	6.88961 (rank : 1809)	NC score	0.009967 (rank : 1793)
Query Neighborhood Hits	1959	Target Neighborhood Hits	197	Shared Neighborhood Hits	78
SwissProt Accessions	P98082, Q13598, Q9BTY0, Q9UK04	Gene names	DAB2, DOC2
Domain Architecture
Description	Disabled homolog 2 (Differentially expressed protein 2) (DOC-2).

DAZP2_HUMAN
θ value	6.88961 (rank : 1810)	NC score	0.005426 (rank : 1879)
Query Neighborhood Hits	1959	Target Neighborhood Hits	33	Shared Neighborhood Hits	13
SwissProt Accessions	Q15038	Gene names	DAZAP2, KIAA0058
Domain Architecture	No domain graphic available
Description	DAZ-associated protein 2 (Deleted in azoospermia-associated protein 2).

DAZP2_MOUSE
θ value	6.88961 (rank : 1811)	NC score	0.005952 (rank : 1871)
Query Neighborhood Hits	1959	Target Neighborhood Hits	35	Shared Neighborhood Hits	15
SwissProt Accessions	Q9DCP9, O88675, Q3UVI4	Gene names	Dazap2, Prtb
Domain Architecture	No domain graphic available
Description	DAZ-associated protein 2 (Deleted in azoospermia-associated protein 2) (Proline-rich protein expressed in brain).

DDX18_HUMAN
θ value	6.88961 (rank : 1812)	NC score	-0.006063 (rank : 2048)
Query Neighborhood Hits	1959	Target Neighborhood Hits	124	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NVP1, Q6IAU4, Q92732, Q9BQB7	Gene names	DDX18
Domain Architecture
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb).

DDX46_HUMAN
θ value	6.88961 (rank : 1813)	NC score	-0.001557 (rank : 1997)
Query Neighborhood Hits	1959	Target Neighborhood Hits	357	Shared Neighborhood Hits	56
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

DOK2_MOUSE
θ value	6.88961 (rank : 1814)	NC score	0.016070 (rank : 1700)
Query Neighborhood Hits	1959	Target Neighborhood Hits	244	Shared Neighborhood Hits	112
SwissProt Accessions	O70469, O70272, Q99KL1	Gene names	Dok2, Frip
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)) (Dok- related protein) (Dok-R) (IL-four receptor-interacting protein) (FRIP).

DOT1L_HUMAN
θ value	6.88961 (rank : 1815)	NC score	0.044448 (rank : 1402)
Query Neighborhood Hits	1959	Target Neighborhood Hits	660	Shared Neighborhood Hits	220
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

DTX3_MOUSE
θ value	6.88961 (rank : 1816)	NC score	-0.007003 (rank : 2053)
Query Neighborhood Hits	1959	Target Neighborhood Hits	202	Shared Neighborhood Hits	12
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

ERR1_HUMAN
θ value	6.88961 (rank : 1817)	NC score	-0.008713 (rank : 2060)
Query Neighborhood Hits	1959	Target Neighborhood Hits	157	Shared Neighborhood Hits	37
SwissProt Accessions	P11474, Q14514	Gene names	ESRRA, ERR1, ESRL1, NR3B1
Domain Architecture
Description	Steroid hormone receptor ERR1 (Estrogen-related receptor, alpha) (ERR- alpha) (Estrogen receptor-like 1).

EYA4_MOUSE
θ value	6.88961 (rank : 1818)	NC score	0.000981 (rank : 1956)
Query Neighborhood Hits	1959	Target Neighborhood Hits	74	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Z191	Gene names	Eya4
Domain Architecture
Description	Eyes absent homolog 4 (EC 3.1.3.48).

FGD1_MOUSE
θ value	6.88961 (rank : 1819)	NC score	0.015160 (rank : 1716)
Query Neighborhood Hits	1959	Target Neighborhood Hits	387	Shared Neighborhood Hits	127
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FILA_HUMAN
θ value	6.88961 (rank : 1820)	NC score	0.018640 (rank : 1661)
Query Neighborhood Hits	1959	Target Neighborhood Hits	685	Shared Neighborhood Hits	144
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

FMN1A_MOUSE
θ value	6.88961 (rank : 1821)	NC score	0.030229 (rank : 1509)
Query Neighborhood Hits	1959	Target Neighborhood Hits	423	Shared Neighborhood Hits	170
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

FMN1B_MOUSE
θ value	6.88961 (rank : 1822)	NC score	0.029364 (rank : 1516)
Query Neighborhood Hits	1959	Target Neighborhood Hits	447	Shared Neighborhood Hits	168
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

GAK10_HUMAN
θ value	6.88961 (rank : 1823)	NC score	0.017656 (rank : 1671)
Query Neighborhood Hits	1959	Target Neighborhood Hits	289	Shared Neighborhood Hits	136
SwissProt Accessions	P87889, P10263, P10264, Q69385, Q9UKH6	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q33.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K10 Gag protein) (HERV-K107 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GTSE1_MOUSE
θ value	6.88961 (rank : 1824)	NC score	0.026027 (rank : 1546)
Query Neighborhood Hits	1959	Target Neighborhood Hits	245	Shared Neighborhood Hits	119
SwissProt Accessions	Q8R080, O89015, Q9CSG9	Gene names	Gtse1, B99
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (Gtse-1) (B99 protein).

HXA4_MOUSE
θ value	6.88961 (rank : 1825)	NC score	-0.012036 (rank : 2073)
Query Neighborhood Hits	1959	Target Neighborhood Hits	379	Shared Neighborhood Hits	54
SwissProt Accessions	P06798, Q61684, Q64388, Q8BPE6	Gene names	Hoxa4, Hox-1.4, Hoxa-4
Domain Architecture
Description	Homeobox protein Hox-A4 (Hox-1.4) (Homeobox protein MH-3).

IF3A_MOUSE
θ value	6.88961 (rank : 1826)	NC score	0.023885 (rank : 1574)
Query Neighborhood Hits	1959	Target Neighborhood Hits	871	Shared Neighborhood Hits	115
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

IF4G1_HUMAN
θ value	6.88961 (rank : 1827)	NC score	0.028538 (rank : 1522)
Query Neighborhood Hits	1959	Target Neighborhood Hits	347	Shared Neighborhood Hits	139
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

ITAE_MOUSE
θ value	6.88961 (rank : 1828)	NC score	-0.006442 (rank : 2050)
Query Neighborhood Hits	1959	Target Neighborhood Hits	73	Shared Neighborhood Hits	5
SwissProt Accessions	Q60677	Gene names	Itgae
Domain Architecture
Description	Integrin alpha-E precursor (Integrin alpha M290) (CD103 antigen) [Contains: Integrin alpha-E light chain; Integrin alpha-E heavy chain].

KCNK4_MOUSE
θ value	6.88961 (rank : 1829)	NC score	-0.000241 (rank : 1980)
Query Neighborhood Hits	1959	Target Neighborhood Hits	118	Shared Neighborhood Hits	33
SwissProt Accessions	O88454	Gene names	Kcnk4, Traak
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK).

KIF17_MOUSE
θ value	6.88961 (rank : 1830)	NC score	0.000325 (rank : 1967)
Query Neighborhood Hits	1959	Target Neighborhood Hits	452	Shared Neighborhood Hits	67
SwissProt Accessions	Q99PW8	Gene names	Kif17
Domain Architecture
Description	Kinesin-like protein KIF17 (MmKIF17).

LRP11_HUMAN
θ value	6.88961 (rank : 1831)	NC score	0.000308 (rank : 1968)
Query Neighborhood Hits	1959	Target Neighborhood Hits	82	Shared Neighborhood Hits	8
SwissProt Accessions	Q86VZ4, Q5VYC0, Q96SN6	Gene names	LRP11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.

MBD6_HUMAN
θ value	6.88961 (rank : 1832)	NC score	0.064914 (rank : 1254)
Query Neighborhood Hits	1959	Target Neighborhood Hits	349	Shared Neighborhood Hits	167
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

MCRS1_HUMAN
θ value	6.88961 (rank : 1833)	NC score	0.003316 (rank : 1910)
Query Neighborhood Hits	1959	Target Neighborhood Hits	23	Shared Neighborhood Hits	9
SwissProt Accessions	Q96EZ8, O14742, O75497, Q6VN53	Gene names	MCRS1, MSP58
Domain Architecture
Description	Microspherule protein 1 (58 kDa microspherule protein) (Cell cycle- regulated factor p78) (MCRS2).

N4BP3_HUMAN
θ value	6.88961 (rank : 1834)	NC score	0.005882 (rank : 1873)
Query Neighborhood Hits	1959	Target Neighborhood Hits	156	Shared Neighborhood Hits	21
SwissProt Accessions	O15049, Q7Z6I3	Gene names	N4BP3, KIAA0341
Domain Architecture
Description	NEDD4-binding protein 3 (N4BP3).

NR4A1_HUMAN
θ value	6.88961 (rank : 1835)	NC score	-0.009337 (rank : 2062)
Query Neighborhood Hits	1959	Target Neighborhood Hits	133	Shared Neighborhood Hits	21
SwissProt Accessions	P22736	Gene names	NR4A1, GFRP1, HMR, NAK1
Domain Architecture
Description	Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR) (Early response protein NAK1) (TR3 orphan receptor) (ST-59).

NRL_HUMAN
θ value	6.88961 (rank : 1836)	NC score	-0.001044 (rank : 1993)
Query Neighborhood Hits	1959	Target Neighborhood Hits	39	Shared Neighborhood Hits	6
SwissProt Accessions	P54845	Gene names	NRL
Domain Architecture
Description	Neural retina-specific leucine zipper protein (NRL) (D14S46E).

NRX2A_HUMAN
θ value	6.88961 (rank : 1837)	NC score	0.018896 (rank : 1655)
Query Neighborhood Hits	1959	Target Neighborhood Hits	614	Shared Neighborhood Hits	191
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NRX2B_HUMAN
θ value	6.88961 (rank : 1838)	NC score	0.019795 (rank : 1643)
Query Neighborhood Hits	1959	Target Neighborhood Hits	481	Shared Neighborhood Hits	178
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

NUMBL_HUMAN
θ value	6.88961 (rank : 1839)	NC score	0.018961 (rank : 1654)
Query Neighborhood Hits	1959	Target Neighborhood Hits	394	Shared Neighborhood Hits	167
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

PCBP4_MOUSE
θ value	6.88961 (rank : 1840)	NC score	-0.000153 (rank : 1977)
Query Neighborhood Hits	1959	Target Neighborhood Hits	46	Shared Neighborhood Hits	11
SwissProt Accessions	P57724, Q91VR3	Gene names	Pcbp4
Domain Architecture
Description	Poly(rC)-binding protein 4 (Alpha-CP4).

PEF1_HUMAN
θ value	6.88961 (rank : 1841)	NC score	-0.002680 (rank : 2013)
Query Neighborhood Hits	1959	Target Neighborhood Hits	135	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UBV8	Gene names	PEF1, ABP32
Domain Architecture	No domain graphic available
Description	Peflin (PEF protein with a long N-terminal hydrophobic domain) (Penta- EF hand domain-containing protein 1).

PELP1_MOUSE
θ value	6.88961 (rank : 1842)	NC score	0.043499 (rank : 1411)
Query Neighborhood Hits	1959	Target Neighborhood Hits	709	Shared Neighborhood Hits	241
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

PP16A_HUMAN
θ value	6.88961 (rank : 1843)	NC score	0.007269 (rank : 1838)
Query Neighborhood Hits	1959	Target Neighborhood Hits	340	Shared Neighborhood Hits	53
SwissProt Accessions	Q96I34	Gene names	PPP1R16A, MYPT3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase- targeting subunit 3).

RIMS2_HUMAN
θ value	6.88961 (rank : 1844)	NC score	0.017506 (rank : 1677)
Query Neighborhood Hits	1959	Target Neighborhood Hits	342	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

SEM6D_HUMAN
θ value	6.88961 (rank : 1845)	NC score	-0.000275 (rank : 1981)
Query Neighborhood Hits	1959	Target Neighborhood Hits	169	Shared Neighborhood Hits	48
SwissProt Accessions	Q8NFY4, Q8NFY3, Q8NFY5, Q8NFY6, Q8NFY7, Q9P249	Gene names	SEMA6D, KIAA1479
Domain Architecture	No domain graphic available
Description	Semaphorin-6D precursor.

SFR17_HUMAN
θ value	6.88961 (rank : 1846)	NC score	0.026522 (rank : 1536)
Query Neighborhood Hits	1959	Target Neighborhood Hits	325	Shared Neighborhood Hits	66
SwissProt Accessions	Q8TF01, Q5T064, Q6P2B4, Q6P2N4, Q6PJ93, Q6PK36, Q7Z640, Q8TF00, Q96K10, Q96SM5, Q9P076, Q9P0C0, Q9Y4N3	Gene names	SRRP130, C6orf111
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 130 (Serine-arginine-rich- splicing regulatory protein 130) (SRrp130) (SR-rich protein) (SR- related protein).

SI1L2_HUMAN
θ value	6.88961 (rank : 1847)	NC score	-0.001000 (rank : 1990)
Query Neighborhood Hits	1959	Target Neighborhood Hits	131	Shared Neighborhood Hits	18
SwissProt Accessions	Q9P2F8, Q5VXR7, Q5VXR8, Q641Q4, Q8NA38, Q96DZ3, Q9H9F6	Gene names	SIPA1L2, KIAA1389
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

SWP70_MOUSE
θ value	6.88961 (rank : 1848)	NC score	0.026378 (rank : 1539)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1097	Shared Neighborhood Hits	137
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

TACC3_HUMAN
θ value	6.88961 (rank : 1849)	NC score	0.022415 (rank : 1605)
Query Neighborhood Hits	1959	Target Neighborhood Hits	779	Shared Neighborhood Hits	180
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

TCP10_HUMAN
θ value	6.88961 (rank : 1850)	NC score	0.023153 (rank : 1595)
Query Neighborhood Hits	1959	Target Neighborhood Hits	134	Shared Neighborhood Hits	56
SwissProt Accessions	Q12799	Gene names	TCP10, TCP10A
Domain Architecture
Description	T-complex protein 10A homolog.

TCRG1_HUMAN
θ value	6.88961 (rank : 1851)	NC score	0.040202 (rank : 1439)
Query Neighborhood Hits	1959	Target Neighborhood Hits	929	Shared Neighborhood Hits	218
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TM119_MOUSE
θ value	6.88961 (rank : 1852)	NC score	0.003664 (rank : 1905)
Query Neighborhood Hits	1959	Target Neighborhood Hits	30	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R138, Q8BP14	Gene names	Tmem119
Domain Architecture	No domain graphic available
Description	Transmembrane protein 119 precursor.

TMM25_HUMAN
θ value	6.88961 (rank : 1853)	NC score	0.045691 (rank : 1391)
Query Neighborhood Hits	1959	Target Neighborhood Hits	43	Shared Neighborhood Hits	40
SwissProt Accessions	Q86YD3, Q6UW89, Q86UA7, Q96KA6, Q96MW9	Gene names	TMEM25
Domain Architecture	No domain graphic available
Description	Transmembrane protein 25 precursor.

TMM25_MOUSE
θ value	6.88961 (rank : 1854)	NC score	0.049776 (rank : 1364)
Query Neighborhood Hits	1959	Target Neighborhood Hits	46	Shared Neighborhood Hits	44
SwissProt Accessions	Q9DCF1, Q3TMP3, Q6PAK7	Gene names	Tmem25
Domain Architecture	No domain graphic available
Description	Transmembrane protein 25 precursor.

TSYL1_MOUSE
θ value	6.88961 (rank : 1855)	NC score	0.000564 (rank : 1961)
Query Neighborhood Hits	1959	Target Neighborhood Hits	105	Shared Neighborhood Hits	33
SwissProt Accessions	O88852, Q3TKW0	Gene names	Tspyl1, Tspyl
Domain Architecture
Description	Testis-specific Y-encoded-like protein 1 (TSPY-like 1).

TUB_MOUSE
θ value	6.88961 (rank : 1856)	NC score	0.002980 (rank : 1919)
Query Neighborhood Hits	1959	Target Neighborhood Hits	28	Shared Neighborhood Hits	11
SwissProt Accessions	P50586	Gene names	Tub, Rd5
Domain Architecture
Description	Tubby protein.

UBP49_MOUSE
θ value	6.88961 (rank : 1857)	NC score	-0.004364 (rank : 2032)
Query Neighborhood Hits	1959	Target Neighborhood Hits	91	Shared Neighborhood Hits	10
SwissProt Accessions	Q6P9L4	Gene names	Usp49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

VAX1_MOUSE
θ value	6.88961 (rank : 1858)	NC score	-0.014983 (rank : 2086)
Query Neighborhood Hits	1959	Target Neighborhood Hits	351	Shared Neighborhood Hits	35
SwissProt Accessions	Q2NKI2, O88880	Gene names	Vax1
Domain Architecture	No domain graphic available
Description	Ventral anterior homeobox 1.

WASF3_MOUSE
θ value	6.88961 (rank : 1859)	NC score	0.023174 (rank : 1594)
Query Neighborhood Hits	1959	Target Neighborhood Hits	188	Shared Neighborhood Hits	100
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

ZFP13_MOUSE
θ value	6.88961 (rank : 1860)	NC score	-0.027619 (rank : 2117)
Query Neighborhood Hits	1959	Target Neighborhood Hits	771	Shared Neighborhood Hits	66
SwissProt Accessions	P10754, Q80WS0, Q8CDD0	Gene names	Zfp13, Krox-8, Zfp-13
Domain Architecture	No domain graphic available
Description	Zinc finger protein 13 (Zfp-13) (Krox-8 protein).

ZN295_HUMAN
θ value	6.88961 (rank : 1861)	NC score	-0.027706 (rank : 2118)
Query Neighborhood Hits	1959	Target Neighborhood Hits	847	Shared Neighborhood Hits	59
SwissProt Accessions	Q9ULJ3, Q6P4R0	Gene names	ZNF295, KIAA1227, ZBTB21
Domain Architecture
Description	Zinc finger protein 295 (Zinc finger and BTB domain-containing protein 21).

ZN385_HUMAN
θ value	6.88961 (rank : 1862)	NC score	0.032417 (rank : 1496)
Query Neighborhood Hits	1959	Target Neighborhood Hits	614	Shared Neighborhood Hits	230
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

ZN516_MOUSE
θ value	6.88961 (rank : 1863)	NC score	-0.015746 (rank : 2088)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1197	Shared Neighborhood Hits	250
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

AFF1_MOUSE
θ value	8.99809 (rank : 1864)	NC score	0.030728 (rank : 1507)
Query Neighborhood Hits	1959	Target Neighborhood Hits	351	Shared Neighborhood Hits	131
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

ANKR6_HUMAN
θ value	8.99809 (rank : 1865)	NC score	0.006907 (rank : 1844)
Query Neighborhood Hits	1959	Target Neighborhood Hits	439	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

ATF6A_HUMAN
θ value	8.99809 (rank : 1866)	NC score	0.006150 (rank : 1865)
Query Neighborhood Hits	1959	Target Neighborhood Hits	174	Shared Neighborhood Hits	37
SwissProt Accessions	P18850, O15139, Q5VW62, Q6IPB5, Q9UEC9	Gene names	ATF6
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 alpha (Activating transcription factor 6 alpha) (ATF6-alpha).

ATN1_HUMAN
θ value	8.99809 (rank : 1867)	NC score	0.058838 (rank : 1290)
Query Neighborhood Hits	1959	Target Neighborhood Hits	676	Shared Neighborhood Hits	237
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

BAG4_MOUSE
θ value	8.99809 (rank : 1868)	NC score	0.015124 (rank : 1717)
Query Neighborhood Hits	1959	Target Neighborhood Hits	79	Shared Neighborhood Hits	37
SwissProt Accessions	Q8CI61, Q3TRL9, Q91VT5, Q9CWG2	Gene names	Bag4, Sodd
Domain Architecture
Description	BAG family molecular chaperone regulator 4 (BCL2-associated athanogene 4) (BAG-4) (Silencer of death domains).

BAT3_MOUSE
θ value	8.99809 (rank : 1869)	NC score	0.033114 (rank : 1491)
Query Neighborhood Hits	1959	Target Neighborhood Hits	518	Shared Neighborhood Hits	212
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

BCL6_HUMAN
θ value	8.99809 (rank : 1870)	NC score	-0.026003 (rank : 2109)
Query Neighborhood Hits	1959	Target Neighborhood Hits	922	Shared Neighborhood Hits	109
SwissProt Accessions	P41182	Gene names	BCL6, BCL5, LAZ3, ZBTB27, ZNF51
Domain Architecture
Description	B-cell lymphoma 6 protein (BCL-6) (Zinc finger protein 51) (LAZ-3 protein) (BCL-5) (Zinc finger and BTB domain-containing protein 27).

BNC2_HUMAN
θ value	8.99809 (rank : 1871)	NC score	-0.002221 (rank : 2004)
Query Neighborhood Hits	1959	Target Neighborhood Hits	439	Shared Neighborhood Hits	47
SwissProt Accessions	Q6ZN30, Q6T3A3, Q8NAR2, Q9H6J0, Q9NXV0	Gene names	BNC2
Domain Architecture	No domain graphic available
Description	Zinc finger protein basonuclin-2.

BNC2_MOUSE
θ value	8.99809 (rank : 1872)	NC score	-0.002608 (rank : 2010)
Query Neighborhood Hits	1959	Target Neighborhood Hits	456	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BMQ3, Q6T3A4	Gene names	Bnc2
Domain Architecture	No domain graphic available
Description	Zinc finger protein basonuclin-2.

BRD2_HUMAN
θ value	8.99809 (rank : 1873)	NC score	0.002038 (rank : 1932)
Query Neighborhood Hits	1959	Target Neighborhood Hits	242	Shared Neighborhood Hits	63
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

BRD3_HUMAN
θ value	8.99809 (rank : 1874)	NC score	0.010186 (rank : 1789)
Query Neighborhood Hits	1959	Target Neighborhood Hits	369	Shared Neighborhood Hits	92
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

BRD4_HUMAN
θ value	8.99809 (rank : 1875)	NC score	0.034396 (rank : 1478)
Query Neighborhood Hits	1959	Target Neighborhood Hits	851	Shared Neighborhood Hits	282
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

C1QR1_HUMAN
θ value	8.99809 (rank : 1876)	NC score	-0.002633 (rank : 2011)
Query Neighborhood Hits	1959	Target Neighborhood Hits	493	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

C2TA_HUMAN
θ value	8.99809 (rank : 1877)	NC score	0.006877 (rank : 1845)
Query Neighborhood Hits	1959	Target Neighborhood Hits	190	Shared Neighborhood Hits	74
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

CAC1B_MOUSE
θ value	8.99809 (rank : 1878)	NC score	0.005356 (rank : 1880)
Query Neighborhood Hits	1959	Target Neighborhood Hits	351	Shared Neighborhood Hits	114
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CBLB_MOUSE
θ value	8.99809 (rank : 1879)	NC score	0.005777 (rank : 1875)
Query Neighborhood Hits	1959	Target Neighborhood Hits	277	Shared Neighborhood Hits	57
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

CD5R2_MOUSE
θ value	8.99809 (rank : 1880)	NC score	0.007889 (rank : 1826)
Query Neighborhood Hits	1959	Target Neighborhood Hits	57	Shared Neighborhood Hits	34
SwissProt Accessions	O35926, O35277	Gene names	Cdk5r2, Nck5ai
Domain Architecture
Description	Cyclin-dependent kinase 5 activator 2 precursor (CDK5 activator 2) (Cyclin-dependent kinase 5 regulatory subunit 2) (P39) (P39I).

CEBPD_HUMAN
θ value	8.99809 (rank : 1881)	NC score	0.005181 (rank : 1883)
Query Neighborhood Hits	1959	Target Neighborhood Hits	135	Shared Neighborhood Hits	39
SwissProt Accessions	P49716, Q14937	Gene names	CEBPD
Domain Architecture
Description	CCAAT/enhancer-binding protein delta (C/EBP delta) (Nuclear factor NF- IL6-beta) (NF-IL6-beta).

CI066_HUMAN
θ value	8.99809 (rank : 1882)	NC score	0.003372 (rank : 1907)
Query Neighborhood Hits	1959	Target Neighborhood Hits	25	Shared Neighborhood Hits	9
SwissProt Accessions	Q5T8R8, Q96NB0	Gene names	C9orf66
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf66.

CIC_MOUSE
θ value	8.99809 (rank : 1883)	NC score	0.045137 (rank : 1397)
Query Neighborhood Hits	1959	Target Neighborhood Hits	742	Shared Neighborhood Hits	305
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CJ108_HUMAN
θ value	8.99809 (rank : 1884)	NC score	0.026153 (rank : 1543)
Query Neighborhood Hits	1959	Target Neighborhood Hits	165	Shared Neighborhood Hits	80
SwissProt Accessions	Q8N8Z3	Gene names	C10orf108
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C10orf108.

CO1A1_HUMAN
θ value	8.99809 (rank : 1885)	NC score	0.009940 (rank : 1796)
Query Neighborhood Hits	1959	Target Neighborhood Hits	475	Shared Neighborhood Hits	139
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CO7A1_HUMAN
θ value	8.99809 (rank : 1886)	NC score	0.082320 (rank : 1162)
Query Neighborhood Hits	1959	Target Neighborhood Hits	807	Shared Neighborhood Hits	281
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

COIA1_MOUSE
θ value	8.99809 (rank : 1887)	NC score	0.006140 (rank : 1866)
Query Neighborhood Hits	1959	Target Neighborhood Hits	481	Shared Neighborhood Hits	154
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

CP053_MOUSE
θ value	8.99809 (rank : 1888)	NC score	0.006806 (rank : 1848)
Query Neighborhood Hits	1959	Target Neighborhood Hits	38	Shared Neighborhood Hits	14
SwissProt Accessions	Q99L02	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf53 homolog.

CRIP3_HUMAN
θ value	8.99809 (rank : 1889)	NC score	0.000480 (rank : 1962)
Query Neighborhood Hits	1959	Target Neighborhood Hits	104	Shared Neighborhood Hits	15
SwissProt Accessions	Q6Q6R5, Q5T043, Q6Q6R4, Q6Q6R6, Q6Q6R7	Gene names	CRIP3
Domain Architecture	No domain graphic available
Description	Cysteine-rich protein 3 (CRP3) (Chromosome 6 LIM-only protein) (h6LIMo).

CSTN3_HUMAN
θ value	8.99809 (rank : 1890)	NC score	-0.006372 (rank : 2049)
Query Neighborhood Hits	1959	Target Neighborhood Hits	145	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BQT9, O94831	Gene names	CLSTN3, CS3, KIAA0726
Domain Architecture
Description	Calsyntenin-3 precursor.

CSTN3_MOUSE
θ value	8.99809 (rank : 1891)	NC score	-0.005985 (rank : 2047)
Query Neighborhood Hits	1959	Target Neighborhood Hits	142	Shared Neighborhood Hits	9
SwissProt Accessions	Q99JH7	Gene names	Clstn3, Cs3, Cstn3
Domain Architecture
Description	Calsyntenin-3 precursor.

DCP1A_MOUSE
θ value	8.99809 (rank : 1892)	NC score	0.013734 (rank : 1735)
Query Neighborhood Hits	1959	Target Neighborhood Hits	103	Shared Neighborhood Hits	50
SwissProt Accessions	Q91YD3, Q6NZE3	Gene names	Dcp1a, Mitc1, Smif
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (MAD homolog 4-interacting transcription coactivator 1) (Smad4-interacting transcriptional co-activator).

DNMT1_HUMAN
θ value	8.99809 (rank : 1893)	NC score	0.021442 (rank : 1620)
Query Neighborhood Hits	1959	Target Neighborhood Hits	401	Shared Neighborhood Hits	109
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

DPOLL_HUMAN
θ value	8.99809 (rank : 1894)	NC score	-0.000091 (rank : 1975)
Query Neighborhood Hits	1959	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UGP5, Q5JQP5, Q6NUM2, Q9HA10, Q9HB35	Gene names	POLL
Domain Architecture
Description	DNA polymerase lambda (EC 2.7.7.7) (EC 4.2.99.-) (Pol Lambda) (DNA polymerase kappa) (DNA polymerase beta-2) (Pol beta2).

DUX4_HUMAN
θ value	8.99809 (rank : 1895)	NC score	-0.008556 (rank : 2059)
Query Neighborhood Hits	1959	Target Neighborhood Hits	403	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UBX2	Gene names	DUX4, DUX10
Domain Architecture	No domain graphic available
Description	Double homeobox protein 4 (Double homeobox protein 10) (Double homeobox protein 4/10).

EFS_MOUSE
θ value	8.99809 (rank : 1896)	NC score	0.041048 (rank : 1435)
Query Neighborhood Hits	1959	Target Neighborhood Hits	389	Shared Neighborhood Hits	159
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

FMNL_MOUSE
θ value	8.99809 (rank : 1897)	NC score	0.021132 (rank : 1623)
Query Neighborhood Hits	1959	Target Neighborhood Hits	428	Shared Neighborhood Hits	145
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

FOXC1_MOUSE
θ value	8.99809 (rank : 1898)	NC score	0.001409 (rank : 1945)
Query Neighborhood Hits	1959	Target Neighborhood Hits	218	Shared Neighborhood Hits	80
SwissProt Accessions	Q61572, O88409, Q61582	Gene names	Foxc1, Fkh1, Fkhl7, Freac3, Mf1
Domain Architecture
Description	Forkhead box protein C1 (Forkhead-related protein FKHL7) (Forkhead- related transcription factor 3) (FREAC-3) (Transcription factor FKH-1) (Mesoderm/mesenchyme forkhead 1) (MF-1).

FOXE2_HUMAN
θ value	8.99809 (rank : 1899)	NC score	0.000798 (rank : 1959)
Query Neighborhood Hits	1959	Target Neighborhood Hits	236	Shared Neighborhood Hits	82
SwissProt Accessions	Q99526	Gene names	FOXE2
Domain Architecture
Description	Forkhead box protein E2 (HNF-3/fork head-like protein 5) (HFKL5) (HFKH4).

GAK7_HUMAN
θ value	8.99809 (rank : 1900)	NC score	0.009020 (rank : 1807)
Query Neighborhood Hits	1959	Target Neighborhood Hits	90	Shared Neighborhood Hits	48
SwissProt Accessions	Q96PI4, Q9QC08	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q23.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K18 Gag protein) (HERV-K110 Gag protein) (HERV-K(C1a) Gag protein) [Contains: Matrix protein].

GLI2_HUMAN
θ value	8.99809 (rank : 1901)	NC score	-0.022172 (rank : 2095)
Query Neighborhood Hits	1959	Target Neighborhood Hits	971	Shared Neighborhood Hits	159
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

GNAS1_HUMAN
θ value	8.99809 (rank : 1902)	NC score	0.008805 (rank : 1810)
Query Neighborhood Hits	1959	Target Neighborhood Hits	278	Shared Neighborhood Hits	100
SwissProt Accessions	Q5JWF2, O75684, O75685, Q5JW67, Q5JWF1, Q9NY42	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

HD_HUMAN
θ value	8.99809 (rank : 1903)	NC score	0.010956 (rank : 1777)
Query Neighborhood Hits	1959	Target Neighborhood Hits	165	Shared Neighborhood Hits	65
SwissProt Accessions	P42858, Q9UQB7	Gene names	HD, IT15
Domain Architecture
Description	Huntingtin (Huntington disease protein) (HD protein).

HEMGN_MOUSE
θ value	8.99809 (rank : 1904)	NC score	0.011905 (rank : 1762)
Query Neighborhood Hits	1959	Target Neighborhood Hits	81	Shared Neighborhood Hits	42
SwissProt Accessions	Q9ERZ0, Q3TAE6, Q80YT2, Q8CF29	Gene names	Hemgn, Ndr
Domain Architecture	No domain graphic available
Description	Hemogen (Hemopoietic gene protein) (Negative differentiation regulator protein) (mNDR).

HNF3B_HUMAN
θ value	8.99809 (rank : 1905)	NC score	-0.002354 (rank : 2006)
Query Neighborhood Hits	1959	Target Neighborhood Hits	106	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y261, Q8WUW4, Q96DF7	Gene names	FOXA2, HNF3B, TCF3B
Domain Architecture
Description	Hepatocyte nuclear factor 3-beta (HNF-3B) (Forkhead box protein A2).

HSPB8_MOUSE
θ value	8.99809 (rank : 1906)	NC score	-0.000768 (rank : 1985)
Query Neighborhood Hits	1959	Target Neighborhood Hits	34	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JK92	Gene names	Hspb8, Cryac, Hsp22
Domain Architecture
Description	Heat-shock protein beta-8 (HspB8) (Alpha crystallin C chain) (Small stress protein-like protein HSP22).

IER2_HUMAN
θ value	8.99809 (rank : 1907)	NC score	0.003949 (rank : 1896)
Query Neighborhood Hits	1959	Target Neighborhood Hits	29	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BTL4, Q03827, Q2TAZ2	Gene names	IER2, ETR101
Domain Architecture	No domain graphic available
Description	Immediate early response gene 2 protein (Protein ETR101).

IF35_MOUSE
θ value	8.99809 (rank : 1908)	NC score	0.025832 (rank : 1549)
Query Neighborhood Hits	1959	Target Neighborhood Hits	210	Shared Neighborhood Hits	109
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

IL1R1_MOUSE
θ value	8.99809 (rank : 1909)	NC score	0.120941 (rank : 1096)
Query Neighborhood Hits	1959	Target Neighborhood Hits	142	Shared Neighborhood Hits	120
SwissProt Accessions	P13504	Gene names	Il1r1, Il-1r1, Il1ra
Domain Architecture
Description	Interleukin-1 receptor type I precursor (IL-1R-1) (p80) (CD121a antigen).

INOC1_HUMAN
θ value	8.99809 (rank : 1910)	NC score	0.001158 (rank : 1952)
Query Neighborhood Hits	1959	Target Neighborhood Hits	181	Shared Neighborhood Hits	26
SwissProt Accessions	Q9ULG1, Q9NTG6	Gene names	INOC1, KIAA1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-) (hINO80).

IP3KB_HUMAN
θ value	8.99809 (rank : 1911)	NC score	0.006426 (rank : 1856)
Query Neighborhood Hits	1959	Target Neighborhood Hits	124	Shared Neighborhood Hits	40
SwissProt Accessions	P27987, Q5VWL9, Q5VWM0, Q96BZ2, Q96JS1, Q9UH47	Gene names	ITPKB
Domain Architecture
Description	Inositol-trisphosphate 3-kinase B (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase B) (IP3K B) (IP3 3-kinase B) (IP3K-B).

K2002_MOUSE
θ value	8.99809 (rank : 1912)	NC score	0.264036 (rank : 985)
Query Neighborhood Hits	1959	Target Neighborhood Hits	267	Shared Neighborhood Hits	232
SwissProt Accessions	Q69Z38, Q8R365	Gene names	Kiaa2002
Domain Architecture	No domain graphic available
Description	Uncharacterized tyrosine-protein kinase KIAA2002 (EC 2.7.10.2).

KCD12_HUMAN
θ value	8.99809 (rank : 1913)	NC score	-0.004473 (rank : 2033)
Query Neighborhood Hits	1959	Target Neighborhood Hits	64	Shared Neighborhood Hits	7
SwissProt Accessions	Q96CX2	Gene names	KCTD12, C13orf2, KIAA1778, PFET1
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD12 (Pfetin) (Predominantly fetal expressed T1 domain).

KCD18_HUMAN
θ value	8.99809 (rank : 1914)	NC score	0.002612 (rank : 1923)
Query Neighborhood Hits	1959	Target Neighborhood Hits	117	Shared Neighborhood Hits	39
SwissProt Accessions	Q6PI47, Q53T21, Q6NW26, Q6PCD8, Q8N9B7, Q96N73	Gene names	KCTD18
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD18.

KCNH1_MOUSE
θ value	8.99809 (rank : 1915)	NC score	-0.001016 (rank : 1992)
Query Neighborhood Hits	1959	Target Neighborhood Hits	94	Shared Neighborhood Hits	14
SwissProt Accessions	Q60603	Gene names	Kcnh1, Eag
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (EAG1) (m-eag).

KCNQ2_HUMAN
θ value	8.99809 (rank : 1916)	NC score	-0.002370 (rank : 2007)
Query Neighborhood Hits	1959	Target Neighborhood Hits	114	Shared Neighborhood Hits	21
SwissProt Accessions	O43526, O43796, O75580, O95845, Q5VYT8, Q96J59, Q99454	Gene names	KCNQ2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (KQT-like 2).

KIF1C_HUMAN
θ value	8.99809 (rank : 1917)	NC score	-0.004244 (rank : 2031)
Query Neighborhood Hits	1959	Target Neighborhood Hits	128	Shared Neighborhood Hits	28
SwissProt Accessions	O43896, O75186	Gene names	KIF1C, KIAA0706
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF1C.

KR261_HUMAN
θ value	8.99809 (rank : 1918)	NC score	-0.004782 (rank : 2038)
Query Neighborhood Hits	1959	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	Q6PEX3	Gene names	KRTAP26-1, KAP26.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 26-1.

L2GL1_MOUSE
θ value	8.99809 (rank : 1919)	NC score	-0.000619 (rank : 1983)
Query Neighborhood Hits	1959	Target Neighborhood Hits	70	Shared Neighborhood Hits	8
SwissProt Accessions	Q80Y17, Q61856, Q7TNV3, Q8BN92	Gene names	Llgl1, Llglh
Domain Architecture	No domain graphic available
Description	Lethal(2) giant larvae protein homolog 1 (LLGL) (Mlgl) (Mgl-1).

LAMA5_HUMAN
θ value	8.99809 (rank : 1920)	NC score	0.011467 (rank : 1770)
Query Neighborhood Hits	1959	Target Neighborhood Hits	976	Shared Neighborhood Hits	151
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

MYO9B_HUMAN
θ value	8.99809 (rank : 1921)	NC score	0.032462 (rank : 1495)
Query Neighborhood Hits	1959	Target Neighborhood Hits	641	Shared Neighborhood Hits	234
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

NMDE3_MOUSE
θ value	8.99809 (rank : 1922)	NC score	-0.004104 (rank : 2028)
Query Neighborhood Hits	1959	Target Neighborhood Hits	86	Shared Neighborhood Hits	25
SwissProt Accessions	Q01098	Gene names	Grin2c
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 3 precursor (N-methyl D- aspartate receptor subtype 2C) (NR2C) (NMDAR2C).

NOL3_MOUSE
θ value	8.99809 (rank : 1923)	NC score	0.016042 (rank : 1701)
Query Neighborhood Hits	1959	Target Neighborhood Hits	97	Shared Neighborhood Hits	40
SwissProt Accessions	Q9D1X0	Gene names	Nol3
Domain Architecture
Description	Nucleolar protein 3.

NR1H3_HUMAN
θ value	8.99809 (rank : 1924)	NC score	-0.010797 (rank : 2067)
Query Neighborhood Hits	1959	Target Neighborhood Hits	104	Shared Neighborhood Hits	4
SwissProt Accessions	Q13133, Q96H87	Gene names	NR1H3, LXRA
Domain Architecture
Description	Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear orphan receptor LXR-alpha).

NUCKS_HUMAN
θ value	8.99809 (rank : 1925)	NC score	0.011577 (rank : 1767)
Query Neighborhood Hits	1959	Target Neighborhood Hits	143	Shared Neighborhood Hits	41
SwissProt Accessions	Q9H1E3, Q9H1D6, Q9H723	Gene names	NUCKS1, NUCKS
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (P1).

PCD15_MOUSE
θ value	8.99809 (rank : 1926)	NC score	-0.009499 (rank : 2063)
Query Neighborhood Hits	1959	Target Neighborhood Hits	262	Shared Neighborhood Hits	75
SwissProt Accessions	Q99PJ1	Gene names	Pcdh15
Domain Architecture
Description	Protocadherin-15 precursor.

PININ_HUMAN
θ value	8.99809 (rank : 1927)	NC score	0.036184 (rank : 1468)
Query Neighborhood Hits	1959	Target Neighborhood Hits	753	Shared Neighborhood Hits	140
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

PO121_MOUSE
θ value	8.99809 (rank : 1928)	NC score	0.044729 (rank : 1400)
Query Neighborhood Hits	1959	Target Neighborhood Hits	345	Shared Neighborhood Hits	143
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

PRB4S_HUMAN
θ value	8.99809 (rank : 1929)	NC score	0.073767 (rank : 1197)
Query Neighborhood Hits	1959	Target Neighborhood Hits	330	Shared Neighborhood Hits	165
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

PRCC_HUMAN
θ value	8.99809 (rank : 1930)	NC score	0.018635 (rank : 1662)
Query Neighborhood Hits	1959	Target Neighborhood Hits	109	Shared Neighborhood Hits	55
SwissProt Accessions	Q92733, O00665, O00724	Gene names	PRCC, TPRC
Domain Architecture	No domain graphic available
Description	Proline-rich protein PRCC (Papillary renal cell carcinoma translocation-associated gene protein).

PSD4_MOUSE
θ value	8.99809 (rank : 1931)	NC score	0.001061 (rank : 1954)
Query Neighborhood Hits	1959	Target Neighborhood Hits	78	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BLR5, Q3TE33, Q3TQF5, Q3UD59, Q3UFH9, Q80V44	Gene names	Psd4
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4).

PVRL1_HUMAN
θ value	8.99809 (rank : 1932)	NC score	0.129530 (rank : 1076)
Query Neighborhood Hits	1959	Target Neighborhood Hits	219	Shared Neighborhood Hits	153
SwissProt Accessions	Q15223, O75465, Q9HBE6, Q9HBW2	Gene names	PVRL1, HVEC, PRR1
Domain Architecture
Description	Poliovirus receptor-related protein 1 precursor (Herpes virus entry mediator C) (HveC) (Nectin-1) (Herpesvirus Ig-like receptor) (HIgR) (CD111 antigen).

RBM16_HUMAN
θ value	8.99809 (rank : 1933)	NC score	0.016717 (rank : 1694)
Query Neighborhood Hits	1959	Target Neighborhood Hits	300	Shared Neighborhood Hits	91
SwissProt Accessions	Q9UPN6, Q5TBU6, Q9BQN8, Q9BX43	Gene names	RBM16, KIAA1116
Domain Architecture
Description	Putative RNA-binding protein 16 (RNA-binding motif protein 16).

RECQ5_HUMAN
θ value	8.99809 (rank : 1934)	NC score	0.015181 (rank : 1715)
Query Neighborhood Hits	1959	Target Neighborhood Hits	390	Shared Neighborhood Hits	152
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

SAM14_MOUSE
θ value	8.99809 (rank : 1935)	NC score	0.007518 (rank : 1833)
Query Neighborhood Hits	1959	Target Neighborhood Hits	91	Shared Neighborhood Hits	33
SwissProt Accessions	Q8K070, Q5SWB7, Q8BHE2, Q8C8N5	Gene names	Samd14
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 14.

SF3A1_HUMAN
θ value	8.99809 (rank : 1936)	NC score	0.021559 (rank : 1616)
Query Neighborhood Hits	1959	Target Neighborhood Hits	199	Shared Neighborhood Hits	102
SwissProt Accessions	Q15459	Gene names	SF3A1, SAP114
Domain Architecture
Description	Splicing factor 3 subunit 1 (Spliceosome-associated protein 114) (SAP 114) (SF3a120).

SHC1_MOUSE
θ value	8.99809 (rank : 1937)	NC score	0.036904 (rank : 1463)
Query Neighborhood Hits	1959	Target Neighborhood Hits	180	Shared Neighborhood Hits	64
SwissProt Accessions	P98083, Q3U2Q7, Q8BFY3, Q8K4C6, Q8K4C7	Gene names	Shc1, Shc, ShcA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

SIA7A_HUMAN
θ value	8.99809 (rank : 1938)	NC score	0.008065 (rank : 1823)
Query Neighborhood Hits	1959	Target Neighborhood Hits	177	Shared Neighborhood Hits	69
SwissProt Accessions	Q9NSC7, Q6UW90, Q9NSC6	Gene names	ST6GALNAC1, SIAT7A
Domain Architecture
Description	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (EC 2.4.99.3) (GalNAc alpha-2,6-sialyltransferase I) (ST6GalNAc I) (Sialyltransferase 7A).

SNIP1_MOUSE
θ value	8.99809 (rank : 1939)	NC score	0.008544 (rank : 1814)
Query Neighborhood Hits	1959	Target Neighborhood Hits	113	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BIZ6, Q3V106, Q8BIZ4	Gene names	Snip1
Domain Architecture
Description	Smad nuclear-interacting protein 1.

SNIP_HUMAN
θ value	8.99809 (rank : 1940)	NC score	0.020658 (rank : 1637)
Query Neighborhood Hits	1959	Target Neighborhood Hits	313	Shared Neighborhood Hits	93
SwissProt Accessions	Q9C0H9, Q8N4W8	Gene names	P140, KIAA1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

SOAT1_HUMAN
θ value	8.99809 (rank : 1941)	NC score	-0.000942 (rank : 1989)
Query Neighborhood Hits	1959	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	P35610, Q8N1E4	Gene names	SOAT1, ACACT, ACACT1, ACAT, ACAT1, SOAT, STAT
Domain Architecture
Description	Sterol O-acyltransferase 1 (EC 2.3.1.26) (Cholesterol acyltransferase 1) (Acyl coenzyme A:cholesterol acyltransferase 1) (ACAT-1).

SP110_HUMAN
θ value	8.99809 (rank : 1942)	NC score	0.001574 (rank : 1942)
Query Neighborhood Hits	1959	Target Neighborhood Hits	141	Shared Neighborhood Hits	41
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

TAB3_MOUSE
θ value	8.99809 (rank : 1943)	NC score	0.017921 (rank : 1669)
Query Neighborhood Hits	1959	Target Neighborhood Hits	273	Shared Neighborhood Hits	118
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

TENN_MOUSE
θ value	8.99809 (rank : 1944)	NC score	0.077394 (rank : 1181)
Query Neighborhood Hits	1959	Target Neighborhood Hits	484	Shared Neighborhood Hits	130
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENS4_MOUSE
θ value	8.99809 (rank : 1945)	NC score	0.037212 (rank : 1461)
Query Neighborhood Hits	1959	Target Neighborhood Hits	225	Shared Neighborhood Hits	114
SwissProt Accessions	Q8BZ33, Q3TCM8, Q7TNR5	Gene names	Tns4
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor.

TR13B_HUMAN
θ value	8.99809 (rank : 1946)	NC score	0.002469 (rank : 1928)
Query Neighborhood Hits	1959	Target Neighborhood Hits	24	Shared Neighborhood Hits	8
SwissProt Accessions	O14836, Q7Z6F5	Gene names	TNFRSF13B, TACI
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 13B (Transmembrane activator and CAML interactor) (CD267 antigen).

TRI66_HUMAN
θ value	8.99809 (rank : 1947)	NC score	0.009946 (rank : 1795)
Query Neighborhood Hits	1959	Target Neighborhood Hits	479	Shared Neighborhood Hits	137
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TRY3_HUMAN
θ value	8.99809 (rank : 1948)	NC score	-0.014399 (rank : 2084)
Query Neighborhood Hits	1959	Target Neighborhood Hits	178	Shared Neighborhood Hits	7
SwissProt Accessions	P35030, P15951, Q15665, Q9UQV3	Gene names	PRSS3, PRSS4, TRY3, TRY4
Domain Architecture
Description	Trypsin-3 precursor (EC 3.4.21.4) (Trypsin III) (Brain trypsinogen) (Mesotrypsinogen) (Trypsin IV).

TSKS_HUMAN
θ value	8.99809 (rank : 1949)	NC score	0.006446 (rank : 1855)
Query Neighborhood Hits	1959	Target Neighborhood Hits	220	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UJT2, Q8WXJ0	Gene names	STK22S1, TSKS, TSKS1
Domain Architecture	No domain graphic available
Description	Testis-specific serine kinase substrate (Testis-specific kinase substrate) (STK22 substrate 1).

U2AFM_MOUSE
θ value	8.99809 (rank : 1950)	NC score	0.012817 (rank : 1744)
Query Neighborhood Hits	1959	Target Neighborhood Hits	543	Shared Neighborhood Hits	68
SwissProt Accessions	Q62377	Gene names	Zrsr2, U2af1-rs2, U2af1l2, U2af1rs2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2).

UBN1_HUMAN
θ value	8.99809 (rank : 1951)	NC score	0.013866 (rank : 1734)
Query Neighborhood Hits	1959	Target Neighborhood Hits	170	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NPG3, Q13079, Q9P1P7	Gene names	UBN1
Domain Architecture	No domain graphic available
Description	Ubinuclein (Ubiquitously expressed nuclear protein) (VT4).

VAX1_HUMAN
θ value	8.99809 (rank : 1952)	NC score	-0.014657 (rank : 2085)
Query Neighborhood Hits	1959	Target Neighborhood Hits	355	Shared Neighborhood Hits	37
SwissProt Accessions	Q5SQQ9, Q6ZSX0	Gene names	VAX1
Domain Architecture	No domain graphic available
Description	Ventral anterior homeobox 1.

WASF2_HUMAN
θ value	8.99809 (rank : 1953)	NC score	0.033556 (rank : 1486)
Query Neighborhood Hits	1959	Target Neighborhood Hits	280	Shared Neighborhood Hits	151
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

YLPM1_HUMAN
θ value	8.99809 (rank : 1954)	NC score	0.061640 (rank : 1274)
Query Neighborhood Hits	1959	Target Neighborhood Hits	670	Shared Neighborhood Hits	285
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

ZBT45_HUMAN
θ value	8.99809 (rank : 1955)	NC score	-0.025816 (rank : 2108)
Query Neighborhood Hits	1959	Target Neighborhood Hits	901	Shared Neighborhood Hits	110
SwissProt Accessions	Q96K62	Gene names	ZBTB45, ZNF499
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 45 (Zinc finger protein 499).

ZBTB3_HUMAN
θ value	8.99809 (rank : 1956)	NC score	-0.023548 (rank : 2098)
Query Neighborhood Hits	1959	Target Neighborhood Hits	910	Shared Neighborhood Hits	113
SwissProt Accessions	Q9H5J0	Gene names	ZBTB3
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 3.

ZHX3_MOUSE
θ value	8.99809 (rank : 1957)	NC score	-0.004535 (rank : 2034)
Query Neighborhood Hits	1959	Target Neighborhood Hits	321	Shared Neighborhood Hits	26
SwissProt Accessions	Q8C0Q2, Q80U14	Gene names	Zhx3, Kiaa0395, Tix1
Domain Architecture
Description	Zinc finger and homeodomain protein 3 (Triple homeobox protein 1).

ZN438_HUMAN
θ value	8.99809 (rank : 1958)	NC score	-0.018158 (rank : 2090)
Query Neighborhood Hits	1959	Target Neighborhood Hits	906	Shared Neighborhood Hits	161
SwissProt Accessions	Q7Z4V0, Q5T426, Q658Q4, Q6ZN65	Gene names	ZNF438
Domain Architecture	No domain graphic available
Description	Zinc finger protein 438.

ZO1_MOUSE
θ value	8.99809 (rank : 1959)	NC score	0.017004 (rank : 1687)
Query Neighborhood Hits	1959	Target Neighborhood Hits	453	Shared Neighborhood Hits	152
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ACV1B_HUMAN
θ value	θ > 10 (rank : 1960)	NC score	0.593876 (rank : 788)
Query Neighborhood Hits	1959	Target Neighborhood Hits	753	Shared Neighborhood Hits	735
SwissProt Accessions	P36896, Q15479, Q15480, Q15481, Q15482	Gene names	ACVR1B, ACVRLK4
Domain Architecture
Description	Activin receptor type 1B precursor (EC 2.7.11.30) (ACTR-IB) (Serine/threonine-protein kinase receptor R2) (SKR2) (Activin receptor-like kinase 4) (ALK-4).

ACV1B_MOUSE
θ value	θ > 10 (rank : 1961)	NC score	0.594161 (rank : 787)
Query Neighborhood Hits	1959	Target Neighborhood Hits	753	Shared Neighborhood Hits	735
SwissProt Accessions	Q61271	Gene names	Acvr1b
Domain Architecture
Description	Activin receptor type 1B precursor (EC 2.7.11.30) (ACTR-IB) (Serine/threonine-protein kinase receptor R2) (SKR2).

ACVL1_HUMAN
θ value	θ > 10 (rank : 1962)	NC score	0.554581 (rank : 802)
Query Neighborhood Hits	1959	Target Neighborhood Hits	716	Shared Neighborhood Hits	699
SwissProt Accessions	P37023	Gene names	ACVRL1, ACVRLK1, ALK1
Domain Architecture
Description	Serine/threonine-protein kinase receptor R3 precursor (EC 2.7.11.30) (SKR3) (Activin receptor-like kinase 1) (ALK-1) (TGF-B superfamily receptor type I) (TSR-I).

AL2S2_MOUSE
θ value	θ > 10 (rank : 1963)	NC score	0.711061 (rank : 602)
Query Neighborhood Hits	1959	Target Neighborhood Hits	709	Shared Neighborhood Hits	685
SwissProt Accessions	Q8K4T3, Q6P922, Q8BU86, Q8BXK0, Q8K4T2	Gene names	Als2cr2, Papk
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ALS2CR2 (EC 2.7.11.1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein homolog) (ILP-interacting protein homolog) (Polyploidy-associated protein kinase).

AMGO2_HUMAN
θ value	θ > 10 (rank : 1964)	NC score	0.058697 (rank : 1291)
Query Neighborhood Hits	1959	Target Neighborhood Hits	357	Shared Neighborhood Hits	135
SwissProt Accessions	Q86SJ2, Q7Z4A0, Q96CN8	Gene names	AMIGO2, ALI1
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 2 precursor (AMIGO-2) (Alivin-1) (Differentially expressed in gastric adenocarcinomas) (DEGA).

AMHR2_HUMAN
θ value	θ > 10 (rank : 1965)	NC score	0.498217 (rank : 817)
Query Neighborhood Hits	1959	Target Neighborhood Hits	715	Shared Neighborhood Hits	658
SwissProt Accessions	Q16671, Q13762	Gene names	AMHR2, AMHR
Domain Architecture
Description	Anti-Muellerian hormone type-2 receptor precursor (EC 2.7.11.30) (Anti-Muellerian hormone type II receptor) (AMH type II receptor) (MIS type II receptor) (MISRII) (MRII).

ANKF1_HUMAN
θ value	θ > 10 (rank : 1966)	NC score	0.062380 (rank : 1271)
Query Neighborhood Hits	1959	Target Neighborhood Hits	126	Shared Neighborhood Hits	50
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

ANPRB_HUMAN
θ value	θ > 10 (rank : 1967)	NC score	0.443216 (rank : 828)
Query Neighborhood Hits	1959	Target Neighborhood Hits	646	Shared Neighborhood Hits	571
SwissProt Accessions	P20594, O60871, Q9UQ50	Gene names	NPR2, ANPRB
Domain Architecture
Description	Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor).

ANPRB_MOUSE
θ value	θ > 10 (rank : 1968)	NC score	0.416962 (rank : 832)
Query Neighborhood Hits	1959	Target Neighborhood Hits	607	Shared Neighborhood Hits	545
SwissProt Accessions	Q6VVW5, Q6VVW3, Q6VVW4, Q8CGA9	Gene names	Npr2
Domain Architecture	No domain graphic available
Description	Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor).

BMR1B_HUMAN
θ value	θ > 10 (rank : 1969)	NC score	0.593118 (rank : 790)
Query Neighborhood Hits	1959	Target Neighborhood Hits	760	Shared Neighborhood Hits	736
SwissProt Accessions	O00238, P78366	Gene names	BMPR1B
Domain Architecture
Description	Bone morphogenetic protein receptor type IB precursor (EC 2.7.11.30) (CDw293 antigen).

BMR1B_MOUSE
θ value	θ > 10 (rank : 1970)	NC score	0.594481 (rank : 786)
Query Neighborhood Hits	1959	Target Neighborhood Hits	758	Shared Neighborhood Hits	737
SwissProt Accessions	P36898, Q3TRF2	Gene names	Bmpr1b, Acvrlk6
Domain Architecture
Description	Bone morphogenetic protein receptor type IB precursor (EC 2.7.11.30) (Serine/threonine-protein kinase receptor R6) (SKR6) (Activin receptor-like kinase 6) (ALK-6).

BTNL2_HUMAN
θ value	θ > 10 (rank : 1971)	NC score	0.057309 (rank : 1301)
Query Neighborhood Hits	1959	Target Neighborhood Hits	164	Shared Neighborhood Hits	100
SwissProt Accessions	Q9UIR0, O98261, Q5JYF9, Q5RIF8, Q5SP08, Q5SP09, Q5SRW3, Q5SRW4, Q5SU36, Q95HK0	Gene names	BTNL2
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 2 precursor (BTL-II).

BUB1B_HUMAN
θ value	θ > 10 (rank : 1972)	NC score	0.102275 (rank : 1124)
Query Neighborhood Hits	1959	Target Neighborhood Hits	208	Shared Neighborhood Hits	119
SwissProt Accessions	O60566, O60501, O60627, O60758, O75389, Q96KM4	Gene names	BUB1B, BUBR1, MAD3L
Domain Architecture
Description	Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (hBUBR1) (MAD3/BUB1-related protein kinase) (Mitotic checkpoint kinase MAD3L) (SSK1).

BUB1B_MOUSE
θ value	θ > 10 (rank : 1973)	NC score	0.083005 (rank : 1161)
Query Neighborhood Hits	1959	Target Neighborhood Hits	202	Shared Neighborhood Hits	135
SwissProt Accessions	Q9Z1S0	Gene names	Bub1b, Mad3l
Domain Architecture
Description	Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (MAD3/BUB1-related protein kinase) (Mitotic checkpoint kinase MAD3L).

CD276_HUMAN
θ value	θ > 10 (rank : 1974)	NC score	0.150735 (rank : 1058)
Query Neighborhood Hits	1959	Target Neighborhood Hits	261	Shared Neighborhood Hits	153
SwissProt Accessions	Q5ZPR3, Q6P5Y4, Q6UXI2, Q8NBI8, Q8NC34, Q8NCB6, Q9BXR1	Gene names	CD276, B7H3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3) (4Ig-B7-H3).

CD276_MOUSE
θ value	θ > 10 (rank : 1975)	NC score	0.118353 (rank : 1101)
Query Neighborhood Hits	1959	Target Neighborhood Hits	243	Shared Neighborhood Hits	156
SwissProt Accessions	Q8VE98	Gene names	Cd276, B7h3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3).

CD4_HUMAN
θ value	θ > 10 (rank : 1976)	NC score	0.062663 (rank : 1268)
Query Neighborhood Hits	1959	Target Neighborhood Hits	122	Shared Neighborhood Hits	59
SwissProt Accessions	P01730, Q4ZGK2, Q5U066	Gene names	CD4
Domain Architecture
Description	T-cell surface glycoprotein CD4 precursor (T-cell surface antigen T4/Leu-3).

CD79A_HUMAN
θ value	θ > 10 (rank : 1977)	NC score	0.081182 (rank : 1167)
Query Neighborhood Hits	1959	Target Neighborhood Hits	102	Shared Neighborhood Hits	62
SwissProt Accessions	P11912	Gene names	CD79A, IGA, MB1
Domain Architecture
Description	B-cell antigen receptor complex-associated protein alpha-chain precursor (Ig-alpha) (MB-1 membrane glycoprotein) (Surface IgM- associated protein) (Membrane-bound immunoglobulin-associated protein) (CD79a antigen).

CD80_HUMAN
θ value	θ > 10 (rank : 1978)	NC score	0.080538 (rank : 1172)
Query Neighborhood Hits	1959	Target Neighborhood Hits	129	Shared Neighborhood Hits	91
SwissProt Accessions	P33681	Gene names	CD80, CD28LG, CD28LG1, LAB7
Domain Architecture
Description	T-lymphocyte activation antigen CD80 precursor (Activation B7-1 antigen) (CTLA-4 counter-receptor B7.1) (B7) (BB1).

CD80_MOUSE
θ value	θ > 10 (rank : 1979)	NC score	0.078328 (rank : 1179)
Query Neighborhood Hits	1959	Target Neighborhood Hits	136	Shared Neighborhood Hits	93
SwissProt Accessions	Q00609, Q61332	Gene names	Cd80, B7
Domain Architecture
Description	T-lymphocyte activation antigen CD80 precursor (Activation B7-1 antigen) (B7).

CEAM7_HUMAN
θ value	θ > 10 (rank : 1980)	NC score	0.103012 (rank : 1121)
Query Neighborhood Hits	1959	Target Neighborhood Hits	170	Shared Neighborhood Hits	132
SwissProt Accessions	Q14002, O15148, O15149, Q13983, Q9UPJ2	Gene names	CEACAM7, CGM2
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 7 precursor (Carcinoembryonic antigen CGM2).

CEAM8_HUMAN
θ value	θ > 10 (rank : 1981)	NC score	0.178086 (rank : 1024)
Query Neighborhood Hits	1959	Target Neighborhood Hits	264	Shared Neighborhood Hits	212
SwissProt Accessions	P31997, O60399, Q16574	Gene names	CEACAM8, CGM6
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 8 precursor (Carcinoembryonic antigen CGM6) (Nonspecific cross-reacting antigen NCA-95) (CD67 antigen) (CD66b antigen).

CHIN_HUMAN
θ value	θ > 10 (rank : 1982)	NC score	0.065183 (rank : 1252)
Query Neighborhood Hits	1959	Target Neighborhood Hits	227	Shared Neighborhood Hits	67
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIN_MOUSE
θ value	θ > 10 (rank : 1983)	NC score	0.065730 (rank : 1247)
Query Neighborhood Hits	1959	Target Neighborhood Hits	229	Shared Neighborhood Hits	68
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIO_HUMAN
θ value	θ > 10 (rank : 1984)	NC score	0.066348 (rank : 1243)
Query Neighborhood Hits	1959	Target Neighborhood Hits	220	Shared Neighborhood Hits	66
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

CHIO_MOUSE
θ value	θ > 10 (rank : 1985)	NC score	0.059873 (rank : 1286)
Query Neighborhood Hits	1959	Target Neighborhood Hits	130	Shared Neighborhood Hits	38
SwissProt Accessions	Q80XD1, Q9D9W2, Q9ER57	Gene names	Chn2, Arhgap3, Bch
Domain Architecture	No domain graphic available
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

CK024_HUMAN
θ value	θ > 10 (rank : 1986)	NC score	0.064609 (rank : 1256)
Query Neighborhood Hits	1959	Target Neighborhood Hits	408	Shared Neighborhood Hits	214
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

COCA1_HUMAN
θ value	θ > 10 (rank : 1987)	NC score	0.106397 (rank : 1118)
Query Neighborhood Hits	1959	Target Neighborhood Hits	458	Shared Neighborhood Hits	197
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

COCA1_MOUSE
θ value	θ > 10 (rank : 1988)	NC score	0.113808 (rank : 1106)
Query Neighborhood Hits	1959	Target Neighborhood Hits	467	Shared Neighborhood Hits	214
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

COEA1_HUMAN
θ value	θ > 10 (rank : 1989)	NC score	0.073370 (rank : 1201)
Query Neighborhood Hits	1959	Target Neighborhood Hits	427	Shared Neighborhood Hits	169
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

COEA1_MOUSE
θ value	θ > 10 (rank : 1990)	NC score	0.089821 (rank : 1143)
Query Neighborhood Hits	1959	Target Neighborhood Hits	402	Shared Neighborhood Hits	161
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

COKA1_HUMAN
θ value	θ > 10 (rank : 1991)	NC score	0.065241 (rank : 1251)
Query Neighborhood Hits	1959	Target Neighborhood Hits	403	Shared Neighborhood Hits	162
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

CSF3R_HUMAN
θ value	θ > 10 (rank : 1992)	NC score	0.080618 (rank : 1171)
Query Neighborhood Hits	1959	Target Neighborhood Hits	140	Shared Neighborhood Hits	79
SwissProt Accessions	Q99062	Gene names	CSF3R, GCSFR
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

CSF3R_MOUSE
θ value	θ > 10 (rank : 1993)	NC score	0.062370 (rank : 1272)
Query Neighborhood Hits	1959	Target Neighborhood Hits	104	Shared Neighborhood Hits	58
SwissProt Accessions	P40223	Gene names	Csf3r, Csfgr
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

CT075_HUMAN
θ value	θ > 10 (rank : 1994)	NC score	0.067738 (rank : 1231)
Query Neighborhood Hits	1959	Target Neighborhood Hits	387	Shared Neighborhood Hits	128
SwissProt Accessions	Q8WUT4, Q5JWV6, Q9H419	Gene names	C20orf75
Domain Architecture
Description	Uncharacterized protein C20orf75 precursor.

CT075_MOUSE
θ value	θ > 10 (rank : 1995)	NC score	0.050929 (rank : 1348)
Query Neighborhood Hits	1959	Target Neighborhood Hits	358	Shared Neighborhood Hits	106
SwissProt Accessions	P59383	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf75 homolog precursor.

CXAR_MOUSE
θ value	θ > 10 (rank : 1996)	NC score	0.156895 (rank : 1046)
Query Neighborhood Hits	1959	Target Neighborhood Hits	250	Shared Neighborhood Hits	161
SwissProt Accessions	P97792, O09052, Q3ULD0, Q91W66, Q99KG0, Q9DBJ8	Gene names	Cxadr, Car
Domain Architecture
Description	Coxsackievirus and adenovirus receptor homolog precursor (CAR) (mCAR).

DAPP1_HUMAN
θ value	θ > 10 (rank : 1997)	NC score	0.052582 (rank : 1330)
Query Neighborhood Hits	1959	Target Neighborhood Hits	227	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DAPP1_MOUSE
θ value	θ > 10 (rank : 1998)	NC score	0.051274 (rank : 1344)
Query Neighborhood Hits	1959	Target Neighborhood Hits	225	Shared Neighborhood Hits	69
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DCX_HUMAN
θ value	θ > 10 (rank : 1999)	NC score	0.075252 (rank : 1187)
Query Neighborhood Hits	1959	Target Neighborhood Hits	141	Shared Neighborhood Hits	74
SwissProt Accessions	O43602, O43911	Gene names	DCX, DBCN, LISX
Domain Architecture
Description	Neuronal migration protein doublecortin (Lissencephalin-X) (Lis-X) (Doublin).

DCX_MOUSE
θ value	θ > 10 (rank : 2000)	NC score	0.070402 (rank : 1213)
Query Neighborhood Hits	1959	Target Neighborhood Hits	124	Shared Neighborhood Hits	46
SwissProt Accessions	O88809	Gene names	Dcx, Dcn
Domain Architecture
Description	Neuronal migration protein doublecortin (Lissencephalin-X) (Lis-X) (Doublin).

DGKD_HUMAN
θ value	θ > 10 (rank : 2001)	NC score	0.068284 (rank : 1229)
Query Neighborhood Hits	1959	Target Neighborhood Hits	231	Shared Neighborhood Hits	91
SwissProt Accessions	Q16760, Q14158, Q6PK55, Q8NG53	Gene names	DGKD, KIAA0145
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase delta (EC 2.7.1.107) (Diglyceride kinase delta) (DGK-delta) (DAG kinase delta) (130 kDa diacylglycerol kinase).

DGKH_HUMAN
θ value	θ > 10 (rank : 2002)	NC score	0.063661 (rank : 1261)
Query Neighborhood Hits	1959	Target Neighborhood Hits	255	Shared Neighborhood Hits	87
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

DGKQ_HUMAN
θ value	θ > 10 (rank : 2003)	NC score	0.061321 (rank : 1275)
Query Neighborhood Hits	1959	Target Neighborhood Hits	131	Shared Neighborhood Hits	43
SwissProt Accessions	P52824	Gene names	DGKQ, DAGK4
Domain Architecture
Description	Diacylglycerol kinase theta (EC 2.7.1.107) (Diglyceride kinase theta) (DGK-theta) (DAG kinase theta).

EMB_HUMAN
θ value	θ > 10 (rank : 2004)	NC score	0.068700 (rank : 1227)
Query Neighborhood Hits	1959	Target Neighborhood Hits	54	Shared Neighborhood Hits	42
SwissProt Accessions	Q6PCB8	Gene names	EMB
Domain Architecture	No domain graphic available
Description	Embigin precursor.

EMB_MOUSE
θ value	θ > 10 (rank : 2005)	NC score	0.125252 (rank : 1081)
Query Neighborhood Hits	1959	Target Neighborhood Hits	83	Shared Neighborhood Hits	73
SwissProt Accessions	P21995, Q3UFF1, Q8C2J8, Q8C543, Q96C38	Gene names	Emb, Gp70
Domain Architecture
Description	Embigin precursor (Teratocarcinoma glycoprotein Gp-70).

FCERA_HUMAN
θ value	θ > 10 (rank : 2006)	NC score	0.092106 (rank : 1141)
Query Neighborhood Hits	1959	Target Neighborhood Hits	150	Shared Neighborhood Hits	108
SwissProt Accessions	P12319	Gene names	FCER1A, FCE1A
Domain Architecture
Description	High affinity immunoglobulin epsilon receptor alpha-subunit precursor (FcERI) (IgE Fc receptor, alpha-subunit) (Fc-epsilon RI-alpha).

FCG2B_HUMAN
θ value	θ > 10 (rank : 2007)	NC score	0.054148 (rank : 1322)
Query Neighborhood Hits	1959	Target Neighborhood Hits	116	Shared Neighborhood Hits	76
SwissProt Accessions	P31994, O95649, Q53X85, Q5VXA9, Q8NIA1	Gene names	FCGR2B, CD32, FCG2, IGFR2
Domain Architecture
Description	Low affinity immunoglobulin gamma Fc region receptor II-b precursor (Fc-gamma RII-b) (FcRII-b) (IgG Fc receptor II-b) (Fc-gamma-RIIb) (CD32 antigen) (CDw32).

FCG2C_HUMAN
θ value	θ > 10 (rank : 2008)	NC score	0.053817 (rank : 1324)
Query Neighborhood Hits	1959	Target Neighborhood Hits	118	Shared Neighborhood Hits	77
SwissProt Accessions	P31995, O00523, O00524, O00525	Gene names	FCGR2C, CD32, FCG2, IGFR2
Domain Architecture
Description	Low affinity immunoglobulin gamma Fc region receptor II-c precursor (Fc-gamma RII-c) (FcRII-c) (IgG Fc receptor II-c) (Fc-gamma-RIIc) (CD32 antigen) (CDw32).

FCGR1_HUMAN
θ value	θ > 10 (rank : 2009)	NC score	0.086972 (rank : 1150)
Query Neighborhood Hits	1959	Target Neighborhood Hits	145	Shared Neighborhood Hits	99
SwissProt Accessions	P12314, P12315, Q92495, Q92663	Gene names	FCGR1A, FCG1, FCGR1, IGFR1
Domain Architecture
Description	High affinity immunoglobulin gamma Fc receptor I precursor (Fc-gamma RI) (FcRI) (IgG Fc receptor I) (CD64 antigen).

FCGR1_MOUSE
θ value	θ > 10 (rank : 2010)	NC score	0.066540 (rank : 1241)
Query Neighborhood Hits	1959	Target Neighborhood Hits	123	Shared Neighborhood Hits	87
SwissProt Accessions	P26151	Gene names	Fcgr1, Fcg1
Domain Architecture
Description	High affinity immunoglobulin gamma Fc receptor I precursor (Fc-gamma RI) (FcRI) (IgG Fc receptor I).

FCRL2_HUMAN
θ value	θ > 10 (rank : 2011)	NC score	0.233449 (rank : 1000)
Query Neighborhood Hits	1959	Target Neighborhood Hits	251	Shared Neighborhood Hits	189
SwissProt Accessions	Q96LA5, Q6NTA1, Q9BZI4, Q9BZI5, Q9BZI6	Gene names	FCRL2, FCRH2, IFGP4, IRTA4, SPAP1
Domain Architecture	No domain graphic available
Description	Fc receptor-like protein 2 precursor (SH2 domain-containing phosphatase anchor protein 1) (Fc receptor homolog 2) (FcRH2) (Immunoglobulin receptor translocation-associated 4 protein).

FCRL5_HUMAN
θ value	θ > 10 (rank : 2012)	NC score	0.243957 (rank : 995)
Query Neighborhood Hits	1959	Target Neighborhood Hits	267	Shared Neighborhood Hits	214
SwissProt Accessions	Q96RD9, Q495Q2, Q495Q4, Q5VYK9, Q6UY46	Gene names	FCRL5, FCRH5, IRTA2
Domain Architecture	No domain graphic available
Description	Fc receptor-like protein 5 precursor (Immunoglobulin receptor translocation-associated gene 2 protein) (BXMAS1) (CD307 antigen).

FCRLA_HUMAN
θ value	θ > 10 (rank : 2013)	NC score	0.051011 (rank : 1347)
Query Neighborhood Hits	1959	Target Neighborhood Hits	135	Shared Neighborhood Hits	76
SwissProt Accessions	Q7L513, Q5VXA1, Q5VXA2, Q5VXA3, Q5VXB0, Q8NEW4, Q8WXH3, Q96PC6, Q96PJ0, Q96PJ1, Q96PJ2, Q96PJ4, Q9BR57	Gene names	FCRLA, FCRL, FCRL1, FCRLM1, FCRX, FREB
Domain Architecture	No domain graphic available
Description	Fc receptor-like and mucin-like 1 precursor (Fc receptor-like A) (Fc receptor homolog expressed in B-cells) (Fc receptor-related protein X) (FcRX) (Fc receptor-like protein).

FINC_MOUSE
θ value	θ > 10 (rank : 2014)	NC score	0.152630 (rank : 1053)
Query Neighborhood Hits	1959	Target Neighborhood Hits	309	Shared Neighborhood Hits	152
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

FPRP_HUMAN
θ value	θ > 10 (rank : 2015)	NC score	0.063988 (rank : 1260)
Query Neighborhood Hits	1959	Target Neighborhood Hits	130	Shared Neighborhood Hits	85
SwissProt Accessions	Q9P2B2, Q8N2K6	Gene names	PTGFRN, CD9P1, FPRP, KIAA1436
Domain Architecture
Description	Prostaglandin F2 receptor negative regulator precursor (Prostaglandin F2-alpha receptor regulatory protein) (Prostaglandin F2-alpha receptor-associated protein) (CD9 partner 1) (CD9P-1) (CD315 antigen).

FPRP_MOUSE
θ value	θ > 10 (rank : 2016)	NC score	0.059730 (rank : 1287)
Query Neighborhood Hits	1959	Target Neighborhood Hits	116	Shared Neighborhood Hits	66
SwissProt Accessions	Q9WV91	Gene names	Ptgfrn, Fprp
Domain Architecture
Description	Prostaglandin F2 receptor negative regulator precursor (Prostaglandin F2-alpha receptor regulatory protein) (Prostaglandin F2-alpha receptor-associated protein) (CD315 antigen).

GGN_MOUSE
θ value	θ > 10 (rank : 2017)	NC score	0.052357 (rank : 1333)
Query Neighborhood Hits	1959	Target Neighborhood Hits	311	Shared Neighborhood Hits	160
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GRAP2_HUMAN
θ value	θ > 10 (rank : 2018)	NC score	0.069574 (rank : 1219)
Query Neighborhood Hits	1959	Target Neighborhood Hits	304	Shared Neighborhood Hits	73
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

GRAP2_MOUSE
θ value	θ > 10 (rank : 2019)	NC score	0.068111 (rank : 1230)
Query Neighborhood Hits	1959	Target Neighborhood Hits	297	Shared Neighborhood Hits	71
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

GRAP_HUMAN
θ value	θ > 10 (rank : 2020)	NC score	0.073590 (rank : 1200)
Query Neighborhood Hits	1959	Target Neighborhood Hits	307	Shared Neighborhood Hits	80
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

GRAP_MOUSE
θ value	θ > 10 (rank : 2021)	NC score	0.072388 (rank : 1206)
Query Neighborhood Hits	1959	Target Neighborhood Hits	309	Shared Neighborhood Hits	79
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

GRB2_HUMAN
θ value	θ > 10 (rank : 2022)	NC score	0.069784 (rank : 1217)
Query Neighborhood Hits	1959	Target Neighborhood Hits	310	Shared Neighborhood Hits	76
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
θ value	θ > 10 (rank : 2023)	NC score	0.069716 (rank : 1218)
Query Neighborhood Hits	1959	Target Neighborhood Hits	312	Shared Neighborhood Hits	76
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

GRP3_HUMAN
θ value	θ > 10 (rank : 2024)	NC score	0.089524 (rank : 1144)
Query Neighborhood Hits	1959	Target Neighborhood Hits	131	Shared Neighborhood Hits	42
SwissProt Accessions	Q8IV61, O94931	Gene names	RASGRP3, GRP3, KIAA0846
Domain Architecture
Description	RAS guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1).

I12R1_HUMAN
θ value	θ > 10 (rank : 2025)	NC score	0.060101 (rank : 1285)
Query Neighborhood Hits	1959	Target Neighborhood Hits	78	Shared Neighborhood Hits	49
SwissProt Accessions	P42701	Gene names	IL12RB1, IL12R, IL12RB
Domain Architecture
Description	Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) (IL- 12RB1) (CD212 antigen).

I12R2_HUMAN
θ value	θ > 10 (rank : 2026)	NC score	0.102435 (rank : 1123)
Query Neighborhood Hits	1959	Target Neighborhood Hits	163	Shared Neighborhood Hits	97
SwissProt Accessions	Q99665	Gene names	IL12RB2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

I12R2_MOUSE
θ value	θ > 10 (rank : 2027)	NC score	0.102844 (rank : 1122)
Query Neighborhood Hits	1959	Target Neighborhood Hits	143	Shared Neighborhood Hits	92
SwissProt Accessions	P97378	Gene names	Il12rb2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

ICAM1_HUMAN
θ value	θ > 10 (rank : 2028)	NC score	0.072135 (rank : 1209)
Query Neighborhood Hits	1959	Target Neighborhood Hits	80	Shared Neighborhood Hits	67
SwissProt Accessions	P05362, Q96B50	Gene names	ICAM1
Domain Architecture
Description	Intercellular adhesion molecule 1 precursor (ICAM-1) (Major group rhinovirus receptor) (CD54 antigen).

ICAM1_MOUSE
θ value	θ > 10 (rank : 2029)	NC score	0.077363 (rank : 1182)
Query Neighborhood Hits	1959	Target Neighborhood Hits	99	Shared Neighborhood Hits	86
SwissProt Accessions	P13597, Q61828	Gene names	Icam1, Icam-1
Domain Architecture
Description	Intercellular adhesion molecule 1 precursor (ICAM-1) (MALA-2).

ICAM3_HUMAN
θ value	θ > 10 (rank : 2030)	NC score	0.069803 (rank : 1216)
Query Neighborhood Hits	1959	Target Neighborhood Hits	100	Shared Neighborhood Hits	82
SwissProt Accessions	P32942	Gene names	ICAM3
Domain Architecture
Description	Intercellular adhesion molecule 3 precursor (ICAM-3) (ICAM-R) (CDw50) (CD50 antigen).

IGS21_HUMAN
θ value	θ > 10 (rank : 2031)	NC score	0.108016 (rank : 1115)
Query Neighborhood Hits	1959	Target Neighborhood Hits	123	Shared Neighborhood Hits	101
SwissProt Accessions	Q96ID5, Q8NBR8	Gene names	IGSF21
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 21 precursor.

IGS21_MOUSE
θ value	θ > 10 (rank : 2032)	NC score	0.107168 (rank : 1117)
Query Neighborhood Hits	1959	Target Neighborhood Hits	118	Shared Neighborhood Hits	98
SwissProt Accessions	Q7TNR6	Gene names	Igsf21
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 21 precursor.

IGSF2_HUMAN
θ value	θ > 10 (rank : 2033)	NC score	0.066923 (rank : 1239)
Query Neighborhood Hits	1959	Target Neighborhood Hits	208	Shared Neighborhood Hits	94
SwissProt Accessions	Q93033, Q15856	Gene names	IGSF2, CD101, EWI101, V7
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 2 precursor (Glu-Trp-Ile EWI motif- containing protein 101) (EWI-101) (Cell surface glycoprotein V7) (CD101 antigen).

IL1R2_HUMAN
θ value	θ > 10 (rank : 2034)	NC score	0.180444 (rank : 1020)
Query Neighborhood Hits	1959	Target Neighborhood Hits	153	Shared Neighborhood Hits	125
SwissProt Accessions	P27930, Q9UE68	Gene names	IL1R2, IL1RB
Domain Architecture
Description	Interleukin-1 receptor type II precursor (IL-1R-2) (IL-1R-beta) (CD121b antigen) (CDw121b).

IL6RB_HUMAN
θ value	θ > 10 (rank : 2035)	NC score	0.137454 (rank : 1070)
Query Neighborhood Hits	1959	Target Neighborhood Hits	181	Shared Neighborhood Hits	105
SwissProt Accessions	P40189, Q9UQ41	Gene names	IL6ST
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin M receptor) (CD130 antigen) (CDw130).

IL6RB_MOUSE
θ value	θ > 10 (rank : 2036)	NC score	0.116532 (rank : 1103)
Query Neighborhood Hits	1959	Target Neighborhood Hits	168	Shared Neighborhood Hits	104
SwissProt Accessions	Q00560	Gene names	Il6st
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (CD130 antigen).

ILK1_HUMAN
θ value	θ > 10 (rank : 2037)	NC score	0.408234 (rank : 838)
Query Neighborhood Hits	1959	Target Neighborhood Hits	857	Shared Neighborhood Hits	585
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

ILK2_HUMAN
θ value	θ > 10 (rank : 2038)	NC score	0.395238 (rank : 857)
Query Neighborhood Hits	1959	Target Neighborhood Hits	848	Shared Neighborhood Hits	577
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

ILK_MOUSE
θ value	θ > 10 (rank : 2039)	NC score	0.406103 (rank : 842)
Query Neighborhood Hits	1959	Target Neighborhood Hits	858	Shared Neighborhood Hits	586
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

ILRL1_MOUSE
θ value	θ > 10 (rank : 2040)	NC score	0.087202 (rank : 1148)
Query Neighborhood Hits	1959	Target Neighborhood Hits	172	Shared Neighborhood Hits	123
SwissProt Accessions	P14719, Q05208	Gene names	Il1rl1, Ly84, St2, Ste2
Domain Architecture
Description	Interleukin-1 receptor-like 1 precursor (ST2 protein) (T1 protein) (Lymphocyte antigen 84).

ILRL2_HUMAN
θ value	θ > 10 (rank : 2041)	NC score	0.077051 (rank : 1184)
Query Neighborhood Hits	1959	Target Neighborhood Hits	112	Shared Neighborhood Hits	91
SwissProt Accessions	Q9HB29, Q13525, Q45H74	Gene names	IL1RL2, IL1RRP2
Domain Architecture
Description	Interleukin-1 receptor-like 2 precursor (IL-1Rrp2) (Interleukin-1 receptor-related protein 2) (IL1R-rp2).

ITB4_HUMAN
θ value	θ > 10 (rank : 2042)	NC score	0.123152 (rank : 1091)
Query Neighborhood Hits	1959	Target Neighborhood Hits	458	Shared Neighborhood Hits	151
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

JAML1_HUMAN
θ value	θ > 10 (rank : 2043)	NC score	0.052089 (rank : 1336)
Query Neighborhood Hits	1959	Target Neighborhood Hits	108	Shared Neighborhood Hits	55
SwissProt Accessions	Q86YT9, Q5DTC6, Q7Z499, Q8N9I7, Q8NF70	Gene names	AMICA1, JAML
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule-like precursor (Dendritic cell-specific protein CREA7-1) (Adhesion molecule interacting with CXADR antigen 1).

KALM_HUMAN
θ value	θ > 10 (rank : 2044)	NC score	0.110890 (rank : 1108)
Query Neighborhood Hits	1959	Target Neighborhood Hits	114	Shared Neighborhood Hits	71
SwissProt Accessions	P23352	Gene names	KAL1, ADMLX, KAL, KALIG1
Domain Architecture
Description	Anosmin-1 precursor (Kallmann syndrome protein) (Adhesion molecule- like X-linked).

LAG3_HUMAN
θ value	θ > 10 (rank : 2045)	NC score	0.084902 (rank : 1156)
Query Neighborhood Hits	1959	Target Neighborhood Hits	129	Shared Neighborhood Hits	80
SwissProt Accessions	P18627	Gene names	LAG3, FDC
Domain Architecture
Description	Lymphocyte activation gene 3 protein precursor (LAG-3) (FDC protein) (CD223 antigen).

LIFR_HUMAN
θ value	θ > 10 (rank : 2046)	NC score	0.110435 (rank : 1109)
Query Neighborhood Hits	1959	Target Neighborhood Hits	130	Shared Neighborhood Hits	76
SwissProt Accessions	P42702, Q6LCD9	Gene names	LIFR
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (CD118 antigen).

LIFR_MOUSE
θ value	θ > 10 (rank : 2047)	NC score	0.100894 (rank : 1128)
Query Neighborhood Hits	1959	Target Neighborhood Hits	127	Shared Neighborhood Hits	70
SwissProt Accessions	P42703	Gene names	Lifr
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (D-factor/LIF receptor) (CD118 antigen).

MARCS_MOUSE
θ value	θ > 10 (rank : 2048)	NC score	0.052058 (rank : 1337)
Query Neighborhood Hits	1959	Target Neighborhood Hits	227	Shared Neighborhood Hits	98
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

MFAP3_HUMAN
θ value	θ > 10 (rank : 2049)	NC score	0.074539 (rank : 1190)
Query Neighborhood Hits	1959	Target Neighborhood Hits	91	Shared Neighborhood Hits	82
SwissProt Accessions	P55082, Q9NXA7	Gene names	MFAP3
Domain Architecture
Description	Microfibril-associated glycoprotein 3 precursor.

MLKL_HUMAN
θ value	θ > 10 (rank : 2050)	NC score	0.527220 (rank : 815)
Query Neighborhood Hits	1959	Target Neighborhood Hits	600	Shared Neighborhood Hits	565
SwissProt Accessions	Q8NB16, Q8N6V0	Gene names	MLKL
Domain Architecture	No domain graphic available
Description	Mixed lineage kinase domain-like protein.

MOX2R_HUMAN
θ value	θ > 10 (rank : 2051)	NC score	0.057961 (rank : 1296)
Query Neighborhood Hits	1959	Target Neighborhood Hits	51	Shared Neighborhood Hits	42
SwissProt Accessions	Q8TD46, Q8TD44, Q8TD45, Q8TD52	Gene names	CD200R1, CD200R, CRTR2, MOX2R, OX2R
Domain Architecture	No domain graphic available
Description	Cell surface glycoprotein OX2 receptor precursor (CD200 cell surface glycoprotein receptor).

MOX2R_MOUSE
θ value	θ > 10 (rank : 2052)	NC score	0.121434 (rank : 1095)
Query Neighborhood Hits	1959	Target Neighborhood Hits	110	Shared Neighborhood Hits	93
SwissProt Accessions	Q9ES57	Gene names	Cd200r1, Mox2r, Ox2r
Domain Architecture	No domain graphic available
Description	Cell surface glycoprotein OX2 receptor precursor (CD200 cell surface glycoprotein receptor).

NCK1_HUMAN
θ value	θ > 10 (rank : 2053)	NC score	0.066984 (rank : 1237)
Query Neighborhood Hits	1959	Target Neighborhood Hits	312	Shared Neighborhood Hits	73
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

NCK2_HUMAN
θ value	θ > 10 (rank : 2054)	NC score	0.066948 (rank : 1238)
Query Neighborhood Hits	1959	Target Neighborhood Hits	310	Shared Neighborhood Hits	75
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

NOLC1_HUMAN
θ value	θ > 10 (rank : 2055)	NC score	0.051969 (rank : 1340)
Query Neighborhood Hits	1959	Target Neighborhood Hits	452	Shared Neighborhood Hits	150
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

NTKL_HUMAN
θ value	θ > 10 (rank : 2056)	NC score	0.255430 (rank : 991)
Query Neighborhood Hits	1959	Target Neighborhood Hits	266	Shared Neighborhood Hits	223
SwissProt Accessions	Q96KG9, Q96G50, Q96KG8, Q96KH1, Q9HAW5, Q9HBL3, Q9NR53	Gene names	SCYL1, GKLP, NTKL, TAPK, TEIF, TRAP
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like protein (SCY1-like protein 1) (Teratoma- associated tyrosine kinase) (Telomerase transcriptional element- interacting factor) (Telomerase regulation-associated protein).

NTKL_MOUSE
θ value	θ > 10 (rank : 2057)	NC score	0.335263 (rank : 920)
Query Neighborhood Hits	1959	Target Neighborhood Hits	326	Shared Neighborhood Hits	290
SwissProt Accessions	Q9EQC5, Q3TST7, Q3UKU0, Q8K222	Gene names	Scyl1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like protein (SCY1-like protein 1) (105 kDa kinase- like protein) (Mitosis-associated kinase-like protein NTKL).

OX2G_HUMAN
θ value	θ > 10 (rank : 2058)	NC score	0.074893 (rank : 1188)
Query Neighborhood Hits	1959	Target Neighborhood Hits	100	Shared Neighborhood Hits	75
SwissProt Accessions	P41217, Q6J2Q6, Q6PIQ4, Q8TB85, Q9H3J3	Gene names	CD200, MOX2
Domain Architecture
Description	OX-2 membrane glycoprotein precursor (CD200 antigen).

OX2G_MOUSE
θ value	θ > 10 (rank : 2059)	NC score	0.086971 (rank : 1151)
Query Neighborhood Hits	1959	Target Neighborhood Hits	105	Shared Neighborhood Hits	82
SwissProt Accessions	O54901, O54816, Q9JHD5	Gene names	Cd200, Mox2
Domain Architecture
Description	OX-2 membrane glycoprotein precursor (MRC OX-2 antigen) (CD200 antigen).

PACE1_HUMAN
θ value	θ > 10 (rank : 2060)	NC score	0.065165 (rank : 1253)
Query Neighborhood Hits	1959	Target Neighborhood Hits	74	Shared Neighborhood Hits	54
SwissProt Accessions	Q8IZE3, Q5THA6, Q5THA8, Q8IZN9, Q96C56, Q9UBK6	Gene names	SCYL3, PACE1
Domain Architecture	No domain graphic available
Description	Protein-associating with the carboxyl-terminal domain of ezrin (Ezrin- binding protein PACE-1) (SCY1-like protein 3).

PACE1_MOUSE
θ value	θ > 10 (rank : 2061)	NC score	0.068849 (rank : 1223)
Query Neighborhood Hits	1959	Target Neighborhood Hits	92	Shared Neighborhood Hits	64
SwissProt Accessions	Q9DBQ7, Q6NY01, Q8BQC9, Q8BRJ1	Gene names	Scyl3, Pace1
Domain Architecture	No domain graphic available
Description	Protein-associating with the carboxyl-terminal domain of ezrin (Ezrin- binding protein PACE-1) (SCY1-like protein 3).

PDL1_MOUSE
θ value	θ > 10 (rank : 2062)	NC score	0.096915 (rank : 1135)
Query Neighborhood Hits	1959	Target Neighborhood Hits	168	Shared Neighborhood Hits	118
SwissProt Accessions	Q9EP73	Gene names	Cd274, B7h1, Pdcd1l1, Pdcd1lg1, Pdl1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

PDL2_HUMAN
θ value	θ > 10 (rank : 2063)	NC score	0.080824 (rank : 1170)
Query Neighborhood Hits	1959	Target Neighborhood Hits	114	Shared Neighborhood Hits	80
SwissProt Accessions	Q9BQ51, Q5T7Z6, Q6JXL8, Q6JXL9	Gene names	PDCD1LG2, B7DC, CD273, PDCD1L2, PDL2
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 2 precursor (Programmed death ligand 2) (PD-L2) (PD-1-ligand 2) (PDCD1 ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD273 antigen).

PDZD8_HUMAN
θ value	θ > 10 (rank : 2064)	NC score	0.074187 (rank : 1196)
Query Neighborhood Hits	1959	Target Neighborhood Hits	185	Shared Neighborhood Hits	68
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

PIGR_HUMAN
θ value	θ > 10 (rank : 2065)	NC score	0.116749 (rank : 1102)
Query Neighborhood Hits	1959	Target Neighborhood Hits	164	Shared Neighborhood Hits	99
SwissProt Accessions	P01833, Q8IZY7	Gene names	PIGR
Domain Architecture
Description	Polymeric-immunoglobulin receptor precursor (Poly-Ig receptor) (PIGR) (Hepatocellular carcinoma-associated protein TB6) [Contains: Secretory component].

PIGR_MOUSE
θ value	θ > 10 (rank : 2066)	NC score	0.125958 (rank : 1080)
Query Neighborhood Hits	1959	Target Neighborhood Hits	214	Shared Neighborhood Hits	128
SwissProt Accessions	O70570	Gene names	Pigr
Domain Architecture
Description	Polymeric-immunoglobulin receptor precursor (Poly-Ig receptor) (PIGR) [Contains: Secretory component].

PRPK_HUMAN
θ value	θ > 10 (rank : 2067)	NC score	0.145635 (rank : 1063)
Query Neighborhood Hits	1959	Target Neighborhood Hits	131	Shared Neighborhood Hits	127
SwissProt Accessions	Q96S44, Q3T977, Q5JZ01, Q96FM7, Q9NQE6	Gene names	TP53RK, C20orf64, PRPK
Domain Architecture
Description	TP53-regulating kinase (EC 2.7.11.1) (p53-related protein kinase) (Nori-2).

PRPK_MOUSE
θ value	θ > 10 (rank : 2068)	NC score	0.144030 (rank : 1065)
Query Neighborhood Hits	1959	Target Neighborhood Hits	139	Shared Neighborhood Hits	129
SwissProt Accessions	Q99PW4, Q91W37, Q9CZ32	Gene names	Tp53rk, Prpk, Trp53rk
Domain Architecture
Description	TP53-regulating kinase (EC 2.7.11.1) (p53-related protein kinase) (Nori-2).

PTPRK_HUMAN
θ value	θ > 10 (rank : 2069)	NC score	0.078157 (rank : 1180)
Query Neighborhood Hits	1959	Target Neighborhood Hits	228	Shared Neighborhood Hits	120
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRK_MOUSE
θ value	θ > 10 (rank : 2070)	NC score	0.079370 (rank : 1175)
Query Neighborhood Hits	1959	Target Neighborhood Hits	223	Shared Neighborhood Hits	118
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRM_HUMAN
θ value	θ > 10 (rank : 2071)	NC score	0.102112 (rank : 1125)
Query Neighborhood Hits	1959	Target Neighborhood Hits	244	Shared Neighborhood Hits	135
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRM_MOUSE
θ value	θ > 10 (rank : 2072)	NC score	0.099662 (rank : 1130)
Query Neighborhood Hits	1959	Target Neighborhood Hits	238	Shared Neighborhood Hits	134
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRT_HUMAN
θ value	θ > 10 (rank : 2073)	NC score	0.085742 (rank : 1155)
Query Neighborhood Hits	1959	Target Neighborhood Hits	217	Shared Neighborhood Hits	112
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

PTPRT_MOUSE
θ value	θ > 10 (rank : 2074)	NC score	0.086344 (rank : 1154)
Query Neighborhood Hits	1959	Target Neighborhood Hits	219	Shared Neighborhood Hits	113
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

PVRL1_MOUSE
θ value	θ > 10 (rank : 2075)	NC score	0.119142 (rank : 1099)
Query Neighborhood Hits	1959	Target Neighborhood Hits	201	Shared Neighborhood Hits	144
SwissProt Accessions	Q9JKF6, Q9ERL5, Q9JI17	Gene names	Pvrl1, Hvec, Prr1
Domain Architecture
Description	Poliovirus receptor-related protein 1 precursor (Herpes virus entry mediator C) (HveC) (Nectin-1) (CD111 antigen).

PVRL2_HUMAN
θ value	θ > 10 (rank : 2076)	NC score	0.096987 (rank : 1134)
Query Neighborhood Hits	1959	Target Neighborhood Hits	185	Shared Neighborhood Hits	122
SwissProt Accessions	Q92692, O75455, Q96J29	Gene names	PVRL2, HVEB, PRR2
Domain Architecture
Description	Poliovirus receptor-related protein 2 precursor (Herpes virus entry mediator B) (HveB) (Nectin-2) (CD112 antigen).

PVRL2_MOUSE
θ value	θ > 10 (rank : 2077)	NC score	0.108623 (rank : 1114)
Query Neighborhood Hits	1959	Target Neighborhood Hits	242	Shared Neighborhood Hits	131
SwissProt Accessions	P32507, Q62096	Gene names	Pvrl2, Mph, Pvr, Pvs
Domain Architecture
Description	Poliovirus receptor-related protein 2 precursor (Murine herpesvirus entry protein B) (mHveB) (Nectin-2) (Poliovirus receptor homolog) (CD112 antigen).

PVR_HUMAN
θ value	θ > 10 (rank : 2078)	NC score	0.109780 (rank : 1112)
Query Neighborhood Hits	1959	Target Neighborhood Hits	195	Shared Neighborhood Hits	120
SwissProt Accessions	P15151, P15152, Q15267, Q15268, Q96BJ1	Gene names	PVR, PVS
Domain Architecture
Description	Poliovirus receptor precursor (Nectin-like protein 5) (Necl-5) (CD155 antigen).

PXK_HUMAN
θ value	θ > 10 (rank : 2079)	NC score	0.126655 (rank : 1079)
Query Neighborhood Hits	1959	Target Neighborhood Hits	216	Shared Neighborhood Hits	154
SwissProt Accessions	Q7Z7A4, Q3BCH4, Q3BCH5, Q3BCH6, Q3BDW1, Q45L83, Q59EX3, Q6PK17, Q6ZN39, Q96CA3, Q96R07, Q9NXB8	Gene names	PXK
Domain Architecture	No domain graphic available
Description	PX domain-containing protein kinase-like protein (Modulator of Na,K- ATPase) (MONaKA).

RASA1_HUMAN
θ value	θ > 10 (rank : 2080)	NC score	0.058431 (rank : 1294)
Query Neighborhood Hits	1959	Target Neighborhood Hits	258	Shared Neighborhood Hits	75
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

RASF1_HUMAN
θ value	θ > 10 (rank : 2081)	NC score	0.058099 (rank : 1295)
Query Neighborhood Hits	1959	Target Neighborhood Hits	62	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NS23, O14571, O60539, O60710, Q9HB04, Q9HB18, Q9NS22, Q9UND4, Q9UND5	Gene names	RASSF1, RDA32
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 1.

RASF1_MOUSE
θ value	θ > 10 (rank : 2082)	NC score	0.071238 (rank : 1210)
Query Neighborhood Hits	1959	Target Neighborhood Hits	74	Shared Neighborhood Hits	35
SwissProt Accessions	Q99MK9, Q9WUF5	Gene names	Rassf1
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 1 (Protein 123F2).

RIMB2_HUMAN
θ value	θ > 10 (rank : 2083)	NC score	0.054934 (rank : 1320)
Query Neighborhood Hits	1959	Target Neighborhood Hits	263	Shared Neighborhood Hits	89
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

RN5A_HUMAN
θ value	θ > 10 (rank : 2084)	NC score	0.140354 (rank : 1067)
Query Neighborhood Hits	1959	Target Neighborhood Hits	608	Shared Neighborhood Hits	339
SwissProt Accessions	Q05823	Gene names	RNASEL, RNS4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

SH21A_HUMAN
θ value	θ > 10 (rank : 2085)	NC score	0.052472 (rank : 1332)
Query Neighborhood Hits	1959	Target Neighborhood Hits	89	Shared Neighborhood Hits	42
SwissProt Accessions	O60880, O95383, O95384, O95385, O95386, Q9UNR0	Gene names	SH2D1A, DSHP, SAP
Domain Architecture
Description	SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP) (Duncan disease SH2-protein).

SH21A_MOUSE
θ value	θ > 10 (rank : 2086)	NC score	0.057694 (rank : 1298)
Query Neighborhood Hits	1959	Target Neighborhood Hits	89	Shared Neighborhood Hits	43
SwissProt Accessions	O88890, Q9QWV6	Gene names	Sh2d1a, Xlp
Domain Architecture
Description	SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP).

SH21B_HUMAN
θ value	θ > 10 (rank : 2087)	NC score	0.057632 (rank : 1299)
Query Neighborhood Hits	1959	Target Neighborhood Hits	101	Shared Neighborhood Hits	44
SwissProt Accessions	O14796, Q5T0L1, Q8NI18, Q969K9	Gene names	SH2D1B, EAT2
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

SH21B_MOUSE
θ value	θ > 10 (rank : 2088)	NC score	0.063334 (rank : 1263)
Query Neighborhood Hits	1959	Target Neighborhood Hits	101	Shared Neighborhood Hits	44
SwissProt Accessions	O35324, Q8C268	Gene names	Sh2d1b, Eat2, Sh2d1b1
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

SHPS1_HUMAN
θ value	θ > 10 (rank : 2089)	NC score	0.065345 (rank : 1250)
Query Neighborhood Hits	1959	Target Neighborhood Hits	455	Shared Neighborhood Hits	111
SwissProt Accessions	P78324, O00683, O43799, Q8N517, Q8TAL8, Q9H0Z2, Q9UDX2, Q9UIJ6, Q9Y4U9	Gene names	SIRPA, BIT, MFR, MYD1, PTPNS1, SHPS1, SIRP
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type substrate 1 precursor (SHP substrate 1) (SHPS-1) (Inhibitory receptor SHPS-1) (Signal- regulatory protein alpha-1) (Sirp-alpha-1) (Sirp-alpha-2) (Sirp-alpha- 3) (MyD-1 antigen) (Brain Ig-like molecule with tyrosine-based activation motifs) (Bit) (Macrophage fusion receptor) (p84) (CD172a antigen).

SIGL9_HUMAN
θ value	θ > 10 (rank : 2090)	NC score	0.065460 (rank : 1249)
Query Neighborhood Hits	1959	Target Neighborhood Hits	76	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y336, Q9BYI9	Gene names	SIGLEC9
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 9 precursor (Siglec-9) (Protein FOAP-9).

SIRB1_HUMAN
θ value	θ > 10 (rank : 2091)	NC score	0.056445 (rank : 1308)
Query Neighborhood Hits	1959	Target Neighborhood Hits	422	Shared Neighborhood Hits	98
SwissProt Accessions	O00241, Q5TFR0, Q8TB12, Q9H1U5, Q9Y4V0	Gene names	SIRPB1
Domain Architecture
Description	Signal-regulatory protein beta-1 precursor (SIRP-beta-1) (CD172b antigen).

SLAP1_HUMAN
θ value	θ > 10 (rank : 2092)	NC score	0.093291 (rank : 1139)
Query Neighborhood Hits	1959	Target Neighborhood Hits	113	Shared Neighborhood Hits	43
SwissProt Accessions	Q13239, Q9UMQ8	Gene names	SLA, SLAP, SLAP1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (hSLAP).

SLAP1_MOUSE
θ value	θ > 10 (rank : 2093)	NC score	0.091961 (rank : 1142)
Query Neighborhood Hits	1959	Target Neighborhood Hits	117	Shared Neighborhood Hits	43
SwissProt Accessions	Q60898, Q8C9Q8, Q8CAT0, Q8CBE9, Q8QZX8	Gene names	Sla, Slap, Slap1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (mSLAP).

SLAP2_HUMAN
θ value	θ > 10 (rank : 2094)	NC score	0.094647 (rank : 1137)
Query Neighborhood Hits	1959	Target Neighborhood Hits	139	Shared Neighborhood Hits	51
SwissProt Accessions	Q9H6Q3, Q5TH27, Q5TH28, Q8WY18, Q96QI4, Q9H135	Gene names	SLA2, C20orf156, SLAP2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2) (Modulator of antigen receptor signaling) (MARS).

SLAP2_MOUSE
θ value	θ > 10 (rank : 2095)	NC score	0.097477 (rank : 1133)
Query Neighborhood Hits	1959	Target Neighborhood Hits	136	Shared Neighborhood Hits	48
SwissProt Accessions	Q8R4L0, Q3UU74, Q8C0K2, Q8VI42, Q9D1Z9	Gene names	Sla2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2).

SORL_MOUSE
θ value	θ > 10 (rank : 2096)	NC score	0.072806 (rank : 1203)
Query Neighborhood Hits	1959	Target Neighborhood Hits	439	Shared Neighborhood Hits	125
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

STAC3_HUMAN
θ value	θ > 10 (rank : 2097)	NC score	0.080259 (rank : 1173)
Query Neighborhood Hits	1959	Target Neighborhood Hits	228	Shared Neighborhood Hits	74
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC3_MOUSE
θ value	θ > 10 (rank : 2098)	NC score	0.080965 (rank : 1168)
Query Neighborhood Hits	1959	Target Neighborhood Hits	232	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC_HUMAN
θ value	θ > 10 (rank : 2099)	NC score	0.077314 (rank : 1183)
Query Neighborhood Hits	1959	Target Neighborhood Hits	276	Shared Neighborhood Hits	91
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

STAC_MOUSE
θ value	θ > 10 (rank : 2100)	NC score	0.083443 (rank : 1160)
Query Neighborhood Hits	1959	Target Neighborhood Hits	268	Shared Neighborhood Hits	92
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

TENA_HUMAN
θ value	θ > 10 (rank : 2101)	NC score	0.050007 (rank : 1358)
Query Neighborhood Hits	1959	Target Neighborhood Hits	631	Shared Neighborhood Hits	136
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

TENR_HUMAN
θ value	θ > 10 (rank : 2102)	NC score	0.078479 (rank : 1178)
Query Neighborhood Hits	1959	Target Neighborhood Hits	526	Shared Neighborhood Hits	142
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

TENR_MOUSE
θ value	θ > 10 (rank : 2103)	NC score	0.074827 (rank : 1189)
Query Neighborhood Hits	1959	Target Neighborhood Hits	531	Shared Neighborhood Hits	136
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

TENX_HUMAN
θ value	θ > 10 (rank : 2104)	NC score	0.061122 (rank : 1277)
Query Neighborhood Hits	1959	Target Neighborhood Hits	789	Shared Neighborhood Hits	190
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

TEX14_HUMAN
θ value	θ > 10 (rank : 2105)	NC score	0.426905 (rank : 830)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1103	Shared Neighborhood Hits	646
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

TEX14_MOUSE
θ value	θ > 10 (rank : 2106)	NC score	0.465645 (rank : 824)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1333	Shared Neighborhood Hits	697
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

TOPK_HUMAN
θ value	θ > 10 (rank : 2107)	NC score	0.577739 (rank : 798)
Query Neighborhood Hits	1959	Target Neighborhood Hits	605	Shared Neighborhood Hits	583
SwissProt Accessions	Q96KB5, Q9NPD9, Q9NYL7, Q9NZK6	Gene names	PBK, TOPK
Domain Architecture	No domain graphic available
Description	T-lymphokine-activated killer cell-originated protein kinase (EC 2.7.12.2) (T-LAK cell-originated protein kinase) (PDZ-binding kinase) (Spermatogenesis-related protein kinase) (SPK) (MAPKK-like protein kinase) (Nori-3).

TOPK_MOUSE
θ value	θ > 10 (rank : 2108)	NC score	0.582944 (rank : 795)
Query Neighborhood Hits	1959	Target Neighborhood Hits	618	Shared Neighborhood Hits	595
SwissProt Accessions	Q9JJ78, Q922V2, Q9D184	Gene names	Pbk, Topk
Domain Architecture	No domain graphic available
Description	T-lymphokine-activated killer cell-originated protein kinase (EC 2.7.12.2) (T-LAK cell-originated protein kinase) (PDZ-binding kinase).

UN13A_HUMAN
θ value	θ > 10 (rank : 2109)	NC score	0.070468 (rank : 1212)
Query Neighborhood Hits	1959	Target Neighborhood Hits	285	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

UN13B_HUMAN
θ value	θ > 10 (rank : 2110)	NC score	0.066624 (rank : 1240)
Query Neighborhood Hits	1959	Target Neighborhood Hits	217	Shared Neighborhood Hits	54
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

UN13B_MOUSE
θ value	θ > 10 (rank : 2111)	NC score	0.064304 (rank : 1258)
Query Neighborhood Hits	1959	Target Neighborhood Hits	210	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

VAV2_HUMAN
θ value	θ > 10 (rank : 2112)	NC score	0.070123 (rank : 1215)
Query Neighborhood Hits	1959	Target Neighborhood Hits	453	Shared Neighborhood Hits	115
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

VAV2_MOUSE
θ value	θ > 10 (rank : 2113)	NC score	0.067714 (rank : 1232)
Query Neighborhood Hits	1959	Target Neighborhood Hits	456	Shared Neighborhood Hits	115
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

VAV3_HUMAN
θ value	θ > 10 (rank : 2114)	NC score	0.072391 (rank : 1205)
Query Neighborhood Hits	1959	Target Neighborhood Hits	398	Shared Neighborhood Hits	107
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

VAV3_MOUSE
θ value	θ > 10 (rank : 2115)	NC score	0.072365 (rank : 1207)
Query Neighborhood Hits	1959	Target Neighborhood Hits	404	Shared Neighborhood Hits	112
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

VAV_HUMAN
θ value	θ > 10 (rank : 2116)	NC score	0.073607 (rank : 1199)
Query Neighborhood Hits	1959	Target Neighborhood Hits	452	Shared Neighborhood Hits	111
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

VAV_MOUSE
θ value	θ > 10 (rank : 2117)	NC score	0.068836 (rank : 1224)
Query Neighborhood Hits	1959	Target Neighborhood Hits	430	Shared Neighborhood Hits	108
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

VRK3_HUMAN
θ value	θ > 10 (rank : 2118)	NC score	0.276386 (rank : 974)
Query Neighborhood Hits	1959	Target Neighborhood Hits	349	Shared Neighborhood Hits	326
SwissProt Accessions	Q8IV63, Q9P2V8	Gene names	VRK3
Domain Architecture
Description	Serine/threonine-protein kinase VRK3 (EC 2.7.11.1) (Vaccinia-related kinase 3).

VRK3_MOUSE
θ value	θ > 10 (rank : 2119)	NC score	0.249058 (rank : 992)
Query Neighborhood Hits	1959	Target Neighborhood Hits	342	Shared Neighborhood Hits	322
SwissProt Accessions	Q8K3G5, Q921W6	Gene names	Vrk3
Domain Architecture
Description	Serine/threonine-protein kinase VRK3 (EC 2.7.11.1) (Vaccinia-related kinase 3).

Hits sorted by NC score

SPEG_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1959	Shared Neighborhood Hits	1959
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SPEG_HUMAN
NC score	0.986780 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1762	Shared Neighborhood Hits	1436
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

MYLK_MOUSE
NC score	0.951002 (rank : 3)	θ value	3.2585e-50 (rank : 7)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1489	Shared Neighborhood Hits	1180
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

MYLK_HUMAN
NC score	0.950171 (rank : 4)	θ value	5.55816e-50 (rank : 9)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1328	Shared Neighborhood Hits	1097
SwissProt Accessions	Q15746, O95796, O95797, O95798, O95799, Q14844, Q16794, Q5MY99, Q5MYA0, Q7Z4J0, Q9C0L5, Q9UBG5, Q9UIT9	Gene names	MYLK, MLCK
Domain Architecture
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

OBSCN_HUMAN
NC score	0.941840 (rank : 5)	θ value	5.85632e-100 (rank : 3)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1931	Shared Neighborhood Hits	1282
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

DUET_HUMAN
NC score	0.897042 (rank : 6)	θ value	2.50074e-42 (rank : 16)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1220	Shared Neighborhood Hits	1013
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

TITIN_HUMAN
NC score	0.889508 (rank : 7)	θ value	2.18062e-54 (rank : 4)
Query Neighborhood Hits	1959	Target Neighborhood Hits	2923	Shared Neighborhood Hits	1341
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

DAPK2_HUMAN
NC score	0.882671 (rank : 8)	θ value	1.11993e-50 (rank : 5)
Query Neighborhood Hits	1959	Target Neighborhood Hits	832	Shared Neighborhood Hits	811
SwissProt Accessions	Q9UIK4, O75892	Gene names	DAPK2
Domain Architecture
Description	Death-associated protein kinase 2 (EC 2.7.11.1) (DAP kinase 2) (DAP- kinase-related protein 1) (DRP-1).

DAPK2_MOUSE
NC score	0.882101 (rank : 9)	θ value	1.46268e-50 (rank : 6)
Query Neighborhood Hits	1959	Target Neighborhood Hits	834	Shared Neighborhood Hits	814
SwissProt Accessions	Q8VDF3, O88861, Q9QYM4	Gene names	Dapk2
Domain Architecture
Description	Death-associated protein kinase 2 (EC 2.7.11.1) (DAP kinase 2) (DAP- kinase-related protein 1) (DRP-1).

ST17A_HUMAN
NC score	0.881514 (rank : 10)	θ value	1.98146e-39 (rank : 19)
Query Neighborhood Hits	1959	Target Neighborhood Hits	843	Shared Neighborhood Hits	813
SwissProt Accessions	Q9UEE5, Q8IVC8	Gene names	STK17A, DRAK1
Domain Architecture
Description	Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 1).

DAPK3_MOUSE
NC score	0.881167 (rank : 11)	θ value	5.55816e-50 (rank : 8)
Query Neighborhood Hits	1959	Target Neighborhood Hits	843	Shared Neighborhood Hits	810
SwissProt Accessions	O54784	Gene names	Dapk3, Zipk
Domain Architecture
Description	Death-associated protein kinase 3 (EC 2.7.11.1) (DAP kinase 3) (DAP- like kinase) (Dlk) (ZIP-kinase).

DAPK3_HUMAN
NC score	0.879936 (rank : 12)	θ value	1.85029e-45 (rank : 12)
Query Neighborhood Hits	1959	Target Neighborhood Hits	945	Shared Neighborhood Hits	816
SwissProt Accessions	O43293	Gene names	DAPK3, ZIPK
Domain Architecture
Description	Death-associated protein kinase 3 (EC 2.7.11.1) (DAP kinase 3) (DAP- like kinase) (Dlk) (ZIP-kinase).

ST17B_MOUSE
NC score	0.879761 (rank : 13)	θ value	8.89434e-40 (rank : 18)
Query Neighborhood Hits	1959	Target Neighborhood Hits	838	Shared Neighborhood Hits	818
SwissProt Accessions	Q8BG48, Q3TNG7, Q8BLV9, Q923E7	Gene names	Stk17b, Drak2
Domain Architecture
Description	Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 2).

ST17B_HUMAN
NC score	0.879715 (rank : 14)	θ value	1.79215e-40 (rank : 17)
Query Neighborhood Hits	1959	Target Neighborhood Hits	833	Shared Neighborhood Hits	814
SwissProt Accessions	O94768	Gene names	STK17B, DRAK2
Domain Architecture
Description	Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 2).

MYLK2_HUMAN
NC score	0.878967 (rank : 15)	θ value	1.56636e-44 (rank : 13)
Query Neighborhood Hits	1959	Target Neighborhood Hits	920	Shared Neighborhood Hits	853
SwissProt Accessions	Q9H1R3, Q96I84	Gene names	MYLK2
Domain Architecture
Description	Myosin light chain kinase 2, skeletal/cardiac muscle (EC 2.7.11.18) (MLCK2).

KPSH1_HUMAN
NC score	0.874065 (rank : 16)	θ value	5.584e-34 (rank : 24)
Query Neighborhood Hits	1959	Target Neighborhood Hits	842	Shared Neighborhood Hits	818
SwissProt Accessions	P11801, Q9NY19	Gene names	PSKH1
Domain Architecture
Description	Serine/threonine-protein kinase H1 (EC 2.7.11.1) (PSK-H1).

KPSH1_MOUSE
NC score	0.874016 (rank : 17)	θ value	1.24399e-33 (rank : 25)
Query Neighborhood Hits	1959	Target Neighborhood Hits	839	Shared Neighborhood Hits	815
SwissProt Accessions	Q91YA2, Q3U3V3	Gene names	Pskh1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase H1 (EC 2.7.11.1) (PSK-H1).

KCC1D_MOUSE
NC score	0.873447 (rank : 18)	θ value	4.27553e-34 (rank : 23)
Query Neighborhood Hits	1959	Target Neighborhood Hits	847	Shared Neighborhood Hits	821
SwissProt Accessions	Q8BW96, Q3U450, Q80W64, Q8BWI7	Gene names	Camk1d
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK) (mCKLiK).

KPSH2_HUMAN
NC score	0.873442 (rank : 19)	θ value	1.08979e-29 (rank : 43)
Query Neighborhood Hits	1959	Target Neighborhood Hits	822	Shared Neighborhood Hits	805
SwissProt Accessions	Q96QS6	Gene names	PSKH2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase H2 (EC 2.7.11.1) (PSK-H2).

DCAK3_HUMAN
NC score	0.873361 (rank : 20)	θ value	8.3442e-30 (rank : 41)
Query Neighborhood Hits	1959	Target Neighborhood Hits	888	Shared Neighborhood Hits	835
SwissProt Accessions	Q9C098	Gene names	DCAMKL3, KIAA1765
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL3 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 3).

KCC1B_MOUSE
NC score	0.873360 (rank : 21)	θ value	5.22648e-32 (rank : 34)
Query Neighborhood Hits	1959	Target Neighborhood Hits	842	Shared Neighborhood Hits	820
SwissProt Accessions	Q9QYK9, Q80W07	Gene names	Pnck
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase type 1B (EC 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase homolog).

KCC1D_HUMAN
NC score	0.873318 (rank : 22)	θ value	4.27553e-34 (rank : 22)
Query Neighborhood Hits	1959	Target Neighborhood Hits	846	Shared Neighborhood Hits	820
SwissProt Accessions	Q8IU85, Q9HD31	Gene names	CAMK1D
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK).

KCC1B_HUMAN
NC score	0.873215 (rank : 23)	θ value	1.98606e-31 (rank : 36)
Query Neighborhood Hits	1959	Target Neighborhood Hits	842	Shared Neighborhood Hits	820
SwissProt Accessions	Q6P2M8	Gene names	PNCK
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase type 1B (EC 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase).

KCC4_HUMAN
NC score	0.873094 (rank : 24)	θ value	1.85889e-29 (rank : 45)
Query Neighborhood Hits	1959	Target Neighborhood Hits	841	Shared Neighborhood Hits	816
SwissProt Accessions	Q16566	Gene names	CAMK4
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type IV (EC 2.7.11.17) (CAM kinase-GR) (CaMK IV).

KCC1A_MOUSE
NC score	0.872801 (rank : 25)	θ value	2.19584e-30 (rank : 38)
Query Neighborhood Hits	1959	Target Neighborhood Hits	845	Shared Neighborhood Hits	820
SwissProt Accessions	Q91YS8	Gene names	Camk1
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha).

DCAK3_MOUSE
NC score	0.872755 (rank : 26)	θ value	6.38894e-30 (rank : 39)
Query Neighborhood Hits	1959	Target Neighborhood Hits	922	Shared Neighborhood Hits	851
SwissProt Accessions	Q8BWQ5, Q1A748	Gene names	Dcamkl3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL3 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 3) (CLICK-I and II-related) (CLr).

KCC1A_HUMAN
NC score	0.872726 (rank : 27)	θ value	1.6813e-30 (rank : 37)
Query Neighborhood Hits	1959	Target Neighborhood Hits	846	Shared Neighborhood Hits	820
SwissProt Accessions	Q14012	Gene names	CAMK1
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha).

KCC4_MOUSE
NC score	0.872673 (rank : 28)	θ value	1.08979e-29 (rank : 42)
Query Neighborhood Hits	1959	Target Neighborhood Hits	899	Shared Neighborhood Hits	827
SwissProt Accessions	P08414, Q61381	Gene names	Camk4
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type IV (EC 2.7.11.17) (CAM kinase-GR) (CaMK IV).

KCC2G_HUMAN
NC score	0.872524 (rank : 29)	θ value	8.06329e-33 (rank : 28)
Query Neighborhood Hits	1959	Target Neighborhood Hits	841	Shared Neighborhood Hits	813
SwissProt Accessions	Q13555, O15378, Q13556, Q5SQZ4	Gene names	CAMK2G
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase type II gamma chain (EC 2.7.11.17) (CaM-kinase II gamma chain) (CaM kinase II gamma subunit) (CaMK-II subunit gamma).

KCC2G_MOUSE
NC score	0.872509 (rank : 30)	θ value	8.06329e-33 (rank : 29)
Query Neighborhood Hits	1959	Target Neighborhood Hits	838	Shared Neighborhood Hits	812
SwissProt Accessions	Q923T9, Q3U3H3, Q8VED3	Gene names	Camk2g
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type II gamma chain (EC 2.7.11.17) (CaM-kinase II gamma chain) (CaM kinase II gamma subunit) (CaMK-II subunit gamma).

KCC1G_MOUSE
NC score	0.871402 (rank : 31)	θ value	5.40856e-29 (rank : 49)
Query Neighborhood Hits	1959	Target Neighborhood Hits	851	Shared Neighborhood Hits	828
SwissProt Accessions	Q91VB2	Gene names	Camk1g
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase type 1G (EC 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM- KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III).

KCC2D_HUMAN
NC score	0.871340 (rank : 32)	θ value	2.77131e-33 (rank : 26)
Query Neighborhood Hits	1959	Target Neighborhood Hits	830	Shared Neighborhood Hits	808
SwissProt Accessions	Q13557, Q9UGH6, Q9UQE9	Gene names	CAMK2D
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type II delta chain (EC 2.7.11.17) (CaM-kinase II delta chain) (CaM kinase II subunit delta) (CaMK-II subunit delta).

KCC1G_HUMAN
NC score	0.871182 (rank : 33)	θ value	9.2256e-29 (rank : 50)
Query Neighborhood Hits	1959	Target Neighborhood Hits	850	Shared Neighborhood Hits	821
SwissProt Accessions	Q96NX5, Q86UH5, Q9Y3J7	Gene names	CAMK1G, VWS1
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase type 1G (EC 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM- KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III).

KCC2B_HUMAN
NC score	0.871003 (rank : 34)	θ value	1.37539e-32 (rank : 32)
Query Neighborhood Hits	1959	Target Neighborhood Hits	866	Shared Neighborhood Hits	821
SwissProt Accessions	Q13554, O95437, O95438, O95599, Q9UGH7, Q9UGH8, Q9UGH9, Q9UNX0, Q9UNX7, Q9UP00, Q9Y5N4, Q9Y6F4	Gene names	CAMK2B, CAM2, CAMKB
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type II beta chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II subunit beta) (CaMK-II subunit beta).

KCC2A_HUMAN
NC score	0.870679 (rank : 35)	θ value	6.17384e-33 (rank : 27)
Query Neighborhood Hits	1959	Target Neighborhood Hits	830	Shared Neighborhood Hits	808
SwissProt Accessions	Q9UQM7, Q9Y352	Gene names	CAMK2A
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type II alpha chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II subunit alpha).

KCC2A_MOUSE
NC score	0.870614 (rank : 36)	θ value	1.0531e-32 (rank : 30)
Query Neighborhood Hits	1959	Target Neighborhood Hits	829	Shared Neighborhood Hits	806
SwissProt Accessions	P11798, Q61284	Gene names	Camk2a
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type II alpha chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II subunit alpha).

KCC2B_MOUSE
NC score	0.869066 (rank : 37)	θ value	1.37539e-32 (rank : 33)
Query Neighborhood Hits	1959	Target Neighborhood Hits	841	Shared Neighborhood Hits	808
SwissProt Accessions	P28652, Q5SVH9	Gene names	Camk2b, Camk2d
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type II beta chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II subunit beta) (CaMK-II subunit beta).

STK33_HUMAN
NC score	0.869002 (rank : 38)	θ value	7.30988e-26 (rank : 74)
Query Neighborhood Hits	1959	Target Neighborhood Hits	879	Shared Neighborhood Hits	827
SwissProt Accessions	Q9BYT3, Q658S6, Q8NEF5	Gene names	STK33
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 33 (EC 2.7.11.1).

CHK2_MOUSE
NC score	0.868757 (rank : 39)	θ value	2.77775e-25 (rank : 83)
Query Neighborhood Hits	1959	Target Neighborhood Hits	860	Shared Neighborhood Hits	817
SwissProt Accessions	Q9Z265	Gene names	Chek2, Chk2, Rad53
Domain Architecture
Description	Serine/threonine-protein kinase Chk2 (EC 2.7.11.1).

PHKG2_MOUSE
NC score	0.867914 (rank : 40)	θ value	1.62847e-25 (rank : 82)
Query Neighborhood Hits	1959	Target Neighborhood Hits	841	Shared Neighborhood Hits	822
SwissProt Accessions	Q9DB30	Gene names	Phkg2
Domain Architecture
Description	Phosphorylase b kinase gamma catalytic chain, testis/liver isoform (EC 2.7.11.19) (PHK-gamma-T) (Phosphorylase kinase subunit gamma 2).

PHKG2_HUMAN
NC score	0.867829 (rank : 41)	θ value	3.28125e-26 (rank : 68)
Query Neighborhood Hits	1959	Target Neighborhood Hits	839	Shared Neighborhood Hits	819
SwissProt Accessions	P15735, P11800	Gene names	PHKG2
Domain Architecture
Description	Phosphorylase b kinase gamma catalytic chain, testis/liver isoform (EC 2.7.11.19) (PHK-gamma-T) (Phosphorylase kinase subunit gamma 2) (PSK-C3).

CHK2_HUMAN
NC score	0.867714 (rank : 42)	θ value	1.5242e-23 (rank : 106)
Query Neighborhood Hits	1959	Target Neighborhood Hits	859	Shared Neighborhood Hits	817
SwissProt Accessions	O96017, Q6QA03, Q6QA04, Q6QA05, Q6QA06, Q6QA07, Q6QA08, Q6QA10, Q6QA11, Q6QA12, Q6QA13, Q9HCQ8, Q9UGF0, Q9UGF1	Gene names	CHEK2, CHK2
Domain Architecture
Description	Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (Cds1).

AURKC_MOUSE
NC score	0.866930 (rank : 43)	θ value	1.16704e-23 (rank : 104)
Query Neighborhood Hits	1959	Target Neighborhood Hits	844	Shared Neighborhood Hits	828
SwissProt Accessions	O88445, Q9JLC2	Gene names	Aurkc, Aie1, Stk13
Domain Architecture
Description	Serine/threonine-protein kinase 13 (EC 2.7.11.1) (Aurora/Ipl1/Eg2 protein 1) (Aurora-C).

PLK4_HUMAN
NC score	0.866311 (rank : 44)	θ value	3.07116e-24 (rank : 94)
Query Neighborhood Hits	1959	Target Neighborhood Hits	884	Shared Neighborhood Hits	834
SwissProt Accessions	O00444, Q8IYF0, Q96Q95	Gene names	PLK4, SAK, STK18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine- protein kinase 18).

PLK4_MOUSE
NC score	0.866061 (rank : 45)	θ value	8.08199e-25 (rank : 85)
Query Neighborhood Hits	1959	Target Neighborhood Hits	879	Shared Neighborhood Hits	832
SwissProt Accessions	Q64702, Q6PEP6, Q78EG6, Q8R0I5, Q9CVR6, Q9CVU6	Gene names	Plk4, Sak, Stk18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine- protein kinase 18).

STK6_MOUSE
NC score	0.866011 (rank : 46)	θ value	1.24688e-25 (rank : 79)
Query Neighborhood Hits	1959	Target Neighborhood Hits	886	Shared Neighborhood Hits	845
SwissProt Accessions	P97477, O35624, Q91YU4	Gene names	Stk6, Ark1, Aurka, Ayk1, Iak1
Domain Architecture
Description	Serine/threonine-protein kinase 6 (EC 2.7.11.1) (Aurora-family kinase 1) (Aurora/IPL1-related kinase 1) (Ipl1- and aurora-related kinase 1) (Aurora-A) (Serine/threonine-protein kinase Ayk1).

STK6_HUMAN
NC score	0.865951 (rank : 47)	θ value	1.92365e-26 (rank : 66)
Query Neighborhood Hits	1959	Target Neighborhood Hits	916	Shared Neighborhood Hits	847
SwissProt Accessions	O14965, O60445, O75873, Q9BQD6, Q9UPG5	Gene names	STK6, AIK, ARK1, AURA, BTAK, STK15
Domain Architecture
Description	Serine/threonine-protein kinase 6 (EC 2.7.11.1) (Serine/threonine kinase 15) (Aurora/IPL1-related kinase 1) (Aurora-related kinase 1) (hARK1) (Aurora-A) (Breast-tumor-amplified kinase).

AURKB_MOUSE
NC score	0.865880 (rank : 48)	θ value	8.63488e-27 (rank : 63)
Query Neighborhood Hits	1959	Target Neighborhood Hits	858	Shared Neighborhood Hits	830
SwissProt Accessions	O70126, Q61882	Gene names	Aurkb, Ark2, Stk1, Stk12, Stk5
Domain Architecture
Description	Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-B) (Aurora- related kinase 2) (Serine/threonine-protein kinase 5) (STK-1).

AURKB_HUMAN
NC score	0.865508 (rank : 49)	θ value	3.17815e-21 (rank : 149)
Query Neighborhood Hits	1959	Target Neighborhood Hits	847	Shared Neighborhood Hits	826
SwissProt Accessions	Q96GD4, O14630, O60446, O95083, Q96DV5, Q9UQ46	Gene names	AURKB, AIK2, AIM1, ARK2, STK12
Domain Architecture
Description	Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-B) (Aurora- and Ipl1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1- related kinase 2) (Aurora-related kinase 2) (STK-1).

AURKC_HUMAN
NC score	0.865287 (rank : 50)	θ value	9.87957e-23 (rank : 116)
Query Neighborhood Hits	1959	Target Neighborhood Hits	847	Shared Neighborhood Hits	826
SwissProt Accessions	Q9UQB9, O60681, O75442, Q9UPK5	Gene names	AURKC, AIE2, AIK3, STK13
Domain Architecture
Description	Serine/threonine-protein kinase 13 (EC 2.7.11.1) (Aurora/Ipl1/Eg2 protein 2) (Aurora/Ipl1-related kinase 3) (Aurora-C).

PHKG1_HUMAN
NC score	0.865148 (rank : 51)	θ value	2.27234e-27 (rank : 62)
Query Neighborhood Hits	1959	Target Neighborhood Hits	838	Shared Neighborhood Hits	818
SwissProt Accessions	Q16816	Gene names	PHKG1, PHKG
Domain Architecture
Description	Phosphorylase b kinase gamma catalytic chain, skeletal muscle isoform (EC 2.7.11.19) (Phosphorylase kinase subunit gamma 1).

ULK3_MOUSE
NC score	0.865122 (rank : 52)	θ value	6.40375e-22 (rank : 140)
Query Neighborhood Hits	1959	Target Neighborhood Hits	872	Shared Neighborhood Hits	824
SwissProt Accessions	Q3U3Q1, Q8K1X6, Q9DBR8	Gene names	Ulk3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3).

BRSK1_HUMAN
NC score	0.864987 (rank : 53)	θ value	3.28125e-26 (rank : 67)
Query Neighborhood Hits	1959	Target Neighborhood Hits	942	Shared Neighborhood Hits	862
SwissProt Accessions	Q8TDC3, Q5J5B5, Q8NDD0, Q8NDR4, Q8TDC2, Q96AV4, Q96JL4	Gene names	BRSK1, KIAA1811, SAD1
Domain Architecture
Description	BR serine/threonine-protein kinase 1 (EC 2.7.11.1) (SAD1 kinase) (SAD1A).

PHKG1_MOUSE
NC score	0.864920 (rank : 54)	θ value	2.35151e-24 (rank : 92)
Query Neighborhood Hits	1959	Target Neighborhood Hits	840	Shared Neighborhood Hits	818
SwissProt Accessions	P07934	Gene names	Phkg1, Phkg
Domain Architecture
Description	Phosphorylase b kinase gamma catalytic chain, skeletal muscle isoform (EC 2.7.11.19) (Phosphorylase kinase subunit gamma 1).

SNRK_HUMAN
NC score	0.864395 (rank : 55)	θ value	5.79196e-23 (rank : 114)
Query Neighborhood Hits	1959	Target Neighborhood Hits	855	Shared Neighborhood Hits	811
SwissProt Accessions	Q9NRH2, Q14706, Q68D15, Q6IQ46, Q9NXI7	Gene names	SNRK, KIAA0096, SNFRK
Domain Architecture	No domain graphic available
Description	SNF-related serine/threonine-protein kinase (EC 2.7.11.1) (SNF1- related kinase).

PLK1_MOUSE
NC score	0.864313 (rank : 56)	θ value	5.42112e-21 (rank : 152)
Query Neighborhood Hits	1959	Target Neighborhood Hits	849	Shared Neighborhood Hits	820
SwissProt Accessions	Q07832	Gene names	Plk1, Plk
Domain Architecture
Description	Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13).

MELK_MOUSE
NC score	0.864235 (rank : 57)	θ value	1.2049e-28 (rank : 51)
Query Neighborhood Hits	1959	Target Neighborhood Hits	860	Shared Neighborhood Hits	822
SwissProt Accessions	Q61846, Q61804, Q6ZQH6	Gene names	Melk, Kiaa0175, Pk38
Domain Architecture	No domain graphic available
Description	Maternal embryonic leucine zipper kinase (EC 2.7.11.1) (Protein kinase PK38) (mPK38).

MELK_HUMAN
NC score	0.863742 (rank : 58)	θ value	3.50572e-28 (rank : 56)
Query Neighborhood Hits	1959	Target Neighborhood Hits	847	Shared Neighborhood Hits	819
SwissProt Accessions	Q14680, Q7L3C3	Gene names	MELK, KIAA0175
Domain Architecture	No domain graphic available
Description	Maternal embryonic leucine zipper kinase (EC 2.7.11.1) (hMELK) (Protein kinase PK38) (hPK38).

NUAK2_HUMAN
NC score	0.863695 (rank : 59)	θ value	1.47289e-26 (rank : 64)
Query Neighborhood Hits	1959	Target Neighborhood Hits	874	Shared Neighborhood Hits	830
SwissProt Accessions	Q9H093	Gene names	NUAK2
Domain Architecture	No domain graphic available
Description	NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (SNF1/AMP kinase-related kinase) (SNARK).

SNRK_MOUSE
NC score	0.863660 (rank : 60)	θ value	6.84181e-24 (rank : 99)
Query Neighborhood Hits	1959	Target Neighborhood Hits	849	Shared Neighborhood Hits	810
SwissProt Accessions	Q8VDU5, Q91WX6	Gene names	Snrk
Domain Architecture	No domain graphic available
Description	SNF-related serine/threonine-protein kinase (EC 2.7.11.1) (SNF1- related kinase).

ULK3_HUMAN
NC score	0.863598 (rank : 61)	θ value	1.29331e-14 (rank : 396)
Query Neighborhood Hits	1959	Target Neighborhood Hits	830	Shared Neighborhood Hits	816
SwissProt Accessions	Q6PHR2, Q9NPN5, Q9UFS4	Gene names	ULK3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3).

PLK3_MOUSE
NC score	0.863583 (rank : 62)	θ value	3.28125e-26 (rank : 69)
Query Neighborhood Hits	1959	Target Neighborhood Hits	863	Shared Neighborhood Hits	826
SwissProt Accessions	Q60806, Q60822, Q9R009	Gene names	Plk3, Cnk, Fnk
Domain Architecture
Description	Serine/threonine-protein kinase PLK3 (EC 2.7.11.21) (Polo-like kinase 3) (PLK-3) (Cytokine-inducible serine/threonine-protein kinase) (FGF- inducible kinase).

PLK1_HUMAN
NC score	0.863476 (rank : 63)	θ value	9.24701e-21 (rank : 156)
Query Neighborhood Hits	1959	Target Neighborhood Hits	849	Shared Neighborhood Hits	821
SwissProt Accessions	P53350, Q15153, Q99746	Gene names	PLK1, PLK
Domain Architecture
Description	Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13).

BRSK2_HUMAN
NC score	0.863405 (rank : 64)	θ value	3.39556e-23 (rank : 110)
Query Neighborhood Hits	1959	Target Neighborhood Hits	897	Shared Neighborhood Hits	841
SwissProt Accessions	Q8IWQ3, O60843, O95099, Q5J5B4, Q8TB60	Gene names	BRSK2, C11orf7, PEN11B, STK29
Domain Architecture
Description	BR serine/threonine-protein kinase 2 (EC 2.7.11.1) (Serine/threonine- protein kinase 29) (SAD1B).

HUNK_MOUSE
NC score	0.863221 (rank : 65)	θ value	2.87452e-22 (rank : 134)
Query Neighborhood Hits	1959	Target Neighborhood Hits	874	Shared Neighborhood Hits	828
SwissProt Accessions	O88866	Gene names	Hunk, Makv
Domain Architecture
Description	Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (Serine/threonine-protein kinase MAK-V).

NUAK2_MOUSE
NC score	0.863193 (rank : 66)	θ value	1.24688e-25 (rank : 78)
Query Neighborhood Hits	1959	Target Neighborhood Hits	878	Shared Neighborhood Hits	832
SwissProt Accessions	Q8BZN4, Q80ZW3, Q8CIC0, Q9DBV0	Gene names	Nuak2
Domain Architecture	No domain graphic available
Description	NUAK family SNF1-like kinase 2 (EC 2.7.11.1).

PLK3_HUMAN
NC score	0.863187 (rank : 67)	θ value	1.37858e-24 (rank : 87)
Query Neighborhood Hits	1959	Target Neighborhood Hits	865	Shared Neighborhood Hits	827
SwissProt Accessions	Q9H4B4, Q15767, Q96CV1	Gene names	PLK3, CNK, FNK, PRK
Domain Architecture
Description	Serine/threonine-protein kinase PLK3 (EC 2.7.11.21) (Polo-like kinase 3) (PLK-3) (Cytokine-inducible serine/threonine-protein kinase) (FGF- inducible kinase) (Proliferation-related kinase).

HUNK_HUMAN
NC score	0.862972 (rank : 68)	θ value	2.20094e-22 (rank : 130)
Query Neighborhood Hits	1959	Target Neighborhood Hits	884	Shared Neighborhood Hits	829
SwissProt Accessions	P57058	Gene names	HUNK, MAKV
Domain Architecture
Description	Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (Serine/threonine-protein kinase MAK-V) (B19).

STK11_HUMAN
NC score	0.862851 (rank : 69)	θ value	2.88119e-14 (rank : 419)
Query Neighborhood Hits	1959	Target Neighborhood Hits	831	Shared Neighborhood Hits	814
SwissProt Accessions	Q15831	Gene names	STK11, LKB1, PJS
Domain Architecture
Description	Serine/threonine-protein kinase 11 (EC 2.7.11.1) (Serine/threonine- protein kinase LKB1) (NY-REN-19 antigen).

KKCC1_MOUSE
NC score	0.862459 (rank : 70)	θ value	3.51386e-20 (rank : 174)
Query Neighborhood Hits	1959	Target Neighborhood Hits	866	Shared Neighborhood Hits	838
SwissProt Accessions	Q8VBY2, Q9R054	Gene names	Camkk1, Camkk
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase kinase 1 (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-kinase kinase alpha) (CaM-KK alpha) (CaMKK alpha) (CaMKK 1) (CaM-kinase IV kinase).

KKCC1_HUMAN
NC score	0.862451 (rank : 71)	θ value	2.06002e-20 (rank : 165)
Query Neighborhood Hits	1959	Target Neighborhood Hits	858	Shared Neighborhood Hits	831
SwissProt Accessions	Q8N5S9, Q9BQH3	Gene names	CAMKK1, CAMKKA
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase kinase 1 (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-kinase kinase alpha) (CaM-KK alpha) (CaMKK alpha) (CaMKK 1) (CaM-kinase IV kinase).

NUAK1_MOUSE
NC score	0.862008 (rank : 72)	θ value	1.09232e-21 (rank : 144)
Query Neighborhood Hits	1959	Target Neighborhood Hits	881	Shared Neighborhood Hits	839
SwissProt Accessions	Q641K5, Q6I6D6, Q8CGE1	Gene names	Nuak1, Kiaa0537
Domain Architecture	No domain graphic available
Description	NUAK family SNF1-like kinase 1 (EC 2.7.11.1).

NUAK1_HUMAN
NC score	0.861932 (rank : 73)	θ value	1.09232e-21 (rank : 143)
Query Neighborhood Hits	1959	Target Neighborhood Hits	874	Shared Neighborhood Hits	831
SwissProt Accessions	O60285, Q96KA8	Gene names	NUAK1, ARK5, KIAA0537
Domain Architecture	No domain graphic available
Description	NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase 5).

KKCC2_MOUSE
NC score	0.861729 (rank : 74)	θ value	1.13037e-18 (rank : 205)
Query Neighborhood Hits	1959	Target Neighborhood Hits	855	Shared Neighborhood Hits	819
SwissProt Accessions	Q8C078, Q80TS0, Q8BXM8, Q8C0G3, Q8CH42, Q8QZT7	Gene names	Camkk2, Kiaa0787
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase kinase 2 (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta).

PLK2_HUMAN
NC score	0.861632 (rank : 75)	θ value	6.84181e-24 (rank : 97)
Query Neighborhood Hits	1959	Target Neighborhood Hits	854	Shared Neighborhood Hits	827
SwissProt Accessions	Q9NYY3, O60679, Q96CV7, Q9UE61	Gene names	PLK2, SNK
Domain Architecture
Description	Serine/threonine-protein kinase PLK2 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-2) (Serine/threonine-protein kinase SNK) (Serum-inducible kinase).

KKCC2_HUMAN
NC score	0.861630 (rank : 76)	θ value	1.13037e-18 (rank : 204)
Query Neighborhood Hits	1959	Target Neighborhood Hits	852	Shared Neighborhood Hits	820
SwissProt Accessions	Q96RR4, O94883, Q8IUG2, Q8IUG3, Q8N3I4, Q8WY03, Q8WY04, Q8WY05, Q8WY06, Q96RP1, Q96RP2, Q96RR3, Q9BWE9, Q9UER3, Q9UES2, Q9Y5N2	Gene names	CAMKK2, CAMKKB, KIAA0787
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase kinase 2 (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta).

MAPK2_HUMAN
NC score	0.861490 (rank : 77)	θ value	8.65492e-19 (rank : 200)
Query Neighborhood Hits	1959	Target Neighborhood Hits	844	Shared Neighborhood Hits	816
SwissProt Accessions	P49137, Q8IYD6	Gene names	MAPKAPK2
Domain Architecture
Description	MAP kinase-activated protein kinase 2 (EC 2.7.11.1) (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAPK-2) (MK2).

PLK2_MOUSE
NC score	0.861313 (rank : 78)	θ value	6.84181e-24 (rank : 98)
Query Neighborhood Hits	1959	Target Neighborhood Hits	849	Shared Neighborhood Hits	825
SwissProt Accessions	P53351	Gene names	Plk2, Snk
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PLK2 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-2) (Serine/threonine-protein kinase SNK) (Serum-inducible kinase).

MAPK2_MOUSE
NC score	0.861119 (rank : 79)	θ value	1.92812e-18 (rank : 215)
Query Neighborhood Hits	1959	Target Neighborhood Hits	831	Shared Neighborhood Hits	807
SwissProt Accessions	P49138, Q6P561	Gene names	Mapkapk2, Rps6kc1
Domain Architecture	No domain graphic available
Description	MAP kinase-activated protein kinase 2 (EC 2.7.11.1) (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAPK-2) (MK2).

AAPK1_HUMAN
NC score	0.860907 (rank : 80)	θ value	2.69047e-20 (rank : 168)
Query Neighborhood Hits	1959	Target Neighborhood Hits	842	Shared Neighborhood Hits	824
SwissProt Accessions	Q13131, O00286, Q5D0E1, Q9UNQ4	Gene names	PRKAA1, AMPK1
Domain Architecture
Description	5'-AMP-activated protein kinase catalytic subunit alpha-1 (EC 2.7.11.1) (AMPK alpha-1 chain).

AAPK1_MOUSE
NC score	0.860738 (rank : 81)	θ value	2.69047e-20 (rank : 169)
Query Neighborhood Hits	1959	Target Neighborhood Hits	843	Shared Neighborhood Hits	824
SwissProt Accessions	Q5EG47	Gene names	Prkaa1
Domain Architecture	No domain graphic available
Description	5'-AMP-activated protein kinase catalytic subunit alpha-1 (EC 2.7.11.1) (AMPK alpha-1 chain).

CHK1_MOUSE
NC score	0.860713 (rank : 82)	θ value	2.7842e-17 (rank : 256)
Query Neighborhood Hits	1959	Target Neighborhood Hits	839	Shared Neighborhood Hits	819
SwissProt Accessions	O35280, O54925, Q8CI40, Q9D0N2	Gene names	Chek1, Chk1
Domain Architecture
Description	Serine/threonine-protein kinase Chk1 (EC 2.7.11.1).

DCAK1_MOUSE
NC score	0.860689 (rank : 83)	θ value	3.50572e-28 (rank : 53)
Query Neighborhood Hits	1959	Target Neighborhood Hits	867	Shared Neighborhood Hits	821
SwissProt Accessions	Q9JLM8, Q6P207	Gene names	Dcamkl1, Dclk
Domain Architecture
Description	Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 1).

DCAK2_MOUSE
NC score	0.860636 (rank : 84)	θ value	3.50572e-28 (rank : 54)
Query Neighborhood Hits	1959	Target Neighborhood Hits	858	Shared Neighborhood Hits	819
SwissProt Accessions	Q6PGN3, Q8BUU0, Q8BX25	Gene names	Dcamkl2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL2 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 2).

DCAK1_HUMAN
NC score	0.860574 (rank : 85)	θ value	1.02001e-27 (rank : 59)
Query Neighborhood Hits	1959	Target Neighborhood Hits	877	Shared Neighborhood Hits	828
SwissProt Accessions	O15075	Gene names	DCAMKL1, KIAA0369
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 1).

CHK1_HUMAN
NC score	0.860198 (rank : 86)	θ value	5.60996e-18 (rank : 228)
Query Neighborhood Hits	1959	Target Neighborhood Hits	843	Shared Neighborhood Hits	817
SwissProt Accessions	O14757	Gene names	CHEK1, CHK1
Domain Architecture
Description	Serine/threonine-protein kinase Chk1 (EC 2.7.11.1).

AAPK2_HUMAN
NC score	0.860185 (rank : 87)	θ value	1.42661e-21 (rank : 145)
Query Neighborhood Hits	1959	Target Neighborhood Hits	843	Shared Neighborhood Hits	824
SwissProt Accessions	P54646, Q9H1E8, Q9UD43	Gene names	PRKAA2, AMPK, AMPK2
Domain Architecture
Description	5'-AMP-activated protein kinase catalytic subunit alpha-2 (EC 2.7.11.1) (AMPK alpha-2 chain).

DCAK2_HUMAN
NC score	0.860176 (rank : 88)	θ value	3.17079e-29 (rank : 47)
Query Neighborhood Hits	1959	Target Neighborhood Hits	862	Shared Neighborhood Hits	820
SwissProt Accessions	Q8N568, Q8N399	Gene names	DCAMKL2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL2 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 2).

TRIO_HUMAN
NC score	0.859922 (rank : 89)	θ value	3.85808e-43 (rank : 15)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1580	Shared Neighborhood Hits	1080
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

STK36_HUMAN
NC score	0.859870 (rank : 90)	θ value	1.05554e-24 (rank : 86)
Query Neighborhood Hits	1959	Target Neighborhood Hits	896	Shared Neighborhood Hits	833
SwissProt Accessions	Q9NRP7, Q8TC32, Q9H9N9, Q9UF35, Q9ULE2	Gene names	STK36, KIAA1278
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog).

SN1L1_MOUSE
NC score	0.859689 (rank : 91)	θ value	1.33217e-27 (rank : 61)
Query Neighborhood Hits	1959	Target Neighborhood Hits	895	Shared Neighborhood Hits	843
SwissProt Accessions	Q60670	Gene names	Snf1lk, Msk
Domain Architecture
Description	Serine/threonine-protein kinase SNF1-like kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) (HRT-20) (Myocardial SNF1- like kinase).

KPCD2_HUMAN
NC score	0.859348 (rank : 92)	θ value	6.40375e-22 (rank : 139)
Query Neighborhood Hits	1959	Target Neighborhood Hits	910	Shared Neighborhood Hits	822
SwissProt Accessions	Q9BZL6, Q8TB08, Q9P0T6, Q9Y3X8	Gene names	PRKD2, PKD2
Domain Architecture
Description	Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2).

MAPK3_MOUSE
NC score	0.859262 (rank : 93)	θ value	1.74391e-19 (rank : 187)
Query Neighborhood Hits	1959	Target Neighborhood Hits	811	Shared Neighborhood Hits	795
SwissProt Accessions	Q3UMW7, Q3T9E6, Q8K0G3	Gene names	Mapkapk3
Domain Architecture	No domain graphic available
Description	MAP kinase-activated protein kinase 3 (EC 2.7.11.1) (MAPK-activated protein kinase 3) (MAPKAP kinase 3) (MAPKAPK-3).

SN1L1_HUMAN
NC score	0.859079 (rank : 94)	θ value	9.54697e-26 (rank : 77)
Query Neighborhood Hits	1959	Target Neighborhood Hits	911	Shared Neighborhood Hits	842
SwissProt Accessions	P57059, Q5R2V5, Q86YJ2	Gene names	SNF1LK
Domain Architecture
Description	Serine/threonine-protein kinase SNF1-like kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase SNF1LK).

MAPK3_HUMAN
NC score	0.858929 (rank : 95)	θ value	2.97466e-19 (rank : 192)
Query Neighborhood Hits	1959	Target Neighborhood Hits	807	Shared Neighborhood Hits	787
SwissProt Accessions	Q16644	Gene names	MAPKAPK3
Domain Architecture	No domain graphic available
Description	MAP kinase-activated protein kinase 3 (EC 2.7.11.1) (MAPK-activated protein kinase 3) (MAPKAP kinase 3) (MAPKAPK-3) (Chromosome 3p kinase) (3pK).

NIM1_MOUSE
NC score	0.858905 (rank : 96)	θ value	8.10077e-17 (rank : 279)
Query Neighborhood Hits	1959	Target Neighborhood Hits	850	Shared Neighborhood Hits	822
SwissProt Accessions	Q8BHI9, Q8BXQ9	Gene names	NIM1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase NIM1 (EC 2.7.11.1).

KPCD1_HUMAN
NC score	0.858869 (rank : 97)	θ value	8.93572e-24 (rank : 101)
Query Neighborhood Hits	1959	Target Neighborhood Hits	901	Shared Neighborhood Hits	820
SwissProt Accessions	Q15139	Gene names	PRKD1, PKD, PKD1, PRKCM
Domain Architecture
Description	Serine/threonine-protein kinase D1 (EC 2.7.11.13) (nPKC-D1) (Protein kinase D) (Protein kinase C mu type) (nPKC-mu).

KPCD1_MOUSE
NC score	0.858581 (rank : 98)	θ value	1.99067e-23 (rank : 107)
Query Neighborhood Hits	1959	Target Neighborhood Hits	891	Shared Neighborhood Hits	821
SwissProt Accessions	Q62101	Gene names	Prkd1, Pkcm, Pkd, Prkcm
Domain Architecture
Description	Serine/threonine-protein kinase D1 (EC 2.7.11.13) (nPKC-D1) (Protein kinase D) (Protein kinase C mu type) (nPKC-mu).

PASK_MOUSE
NC score	0.858311 (rank : 99)	θ value	1.80466e-16 (rank : 299)
Query Neighborhood Hits	1959	Target Neighborhood Hits	867	Shared Neighborhood Hits	817
SwissProt Accessions	Q8CEE6, Q91YD8	Gene names	Pask, Kiaa0135
Domain Architecture
Description	PAS domain-containing serine/threonine-protein kinase (EC 2.7.11.1) (PAS-kinase) (PASKIN).

ULK2_MOUSE
NC score	0.858091 (rank : 100)	θ value	3.76295e-14 (rank : 426)
Query Neighborhood Hits	1959	Target Neighborhood Hits	943	Shared Neighborhood Hits	865
SwissProt Accessions	Q9QY01, Q80TV7, Q9WTP4	Gene names	Ulk2, Kiaa0623
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2) (Serine/threonine-protein kinase Unc51.2).

MARK4_HUMAN
NC score	0.857992 (rank : 101)	θ value	2.20094e-22 (rank : 131)
Query Neighborhood Hits	1959	Target Neighborhood Hits	886	Shared Neighborhood Hits	845
SwissProt Accessions	Q96L34, Q8NG37, Q96JG7, Q96SQ2, Q9BYD8	Gene names	MARK4, KIAA1860, MARKL1
Domain Architecture
Description	MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase-like 1).

ULK1_HUMAN
NC score	0.857943 (rank : 102)	θ value	1.24977e-17 (rank : 246)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1121	Shared Neighborhood Hits	934
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).

ULK2_HUMAN
NC score	0.857888 (rank : 103)	θ value	3.76295e-14 (rank : 425)
Query Neighborhood Hits	1959	Target Neighborhood Hits	979	Shared Neighborhood Hits	876
SwissProt Accessions	Q8IYT8, O75119	Gene names	ULK2, KIAA0623
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2).

NIM1_HUMAN
NC score	0.857810 (rank : 104)	θ value	5.60996e-18 (rank : 231)
Query Neighborhood Hits	1959	Target Neighborhood Hits	850	Shared Neighborhood Hits	820
SwissProt Accessions	Q8IY84	Gene names	NIM1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase NIM1 (EC 2.7.11.1).

ULK1_MOUSE
NC score	0.857725 (rank : 105)	θ value	3.07829e-16 (rank : 309)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1214	Shared Neighborhood Hits	989
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

MARK2_HUMAN
NC score	0.857654 (rank : 106)	θ value	1.29031e-22 (rank : 123)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1056	Shared Neighborhood Hits	914
SwissProt Accessions	Q7KZI7, Q15449, Q15524, Q5XGA3, Q68A18, Q96HB3, Q96RG0	Gene names	MARK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog).

MARK4_MOUSE
NC score	0.857630 (rank : 107)	θ value	2.20094e-22 (rank : 132)
Query Neighborhood Hits	1959	Target Neighborhood Hits	898	Shared Neighborhood Hits	838
SwissProt Accessions	Q8CIP4, Q80T81	Gene names	Mark4, Kiaa1860
Domain Architecture	No domain graphic available
Description	MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1).

K0999_MOUSE
NC score	0.857419 (rank : 108)	θ value	9.87957e-23 (rank : 118)
Query Neighborhood Hits	1959	Target Neighborhood Hits	931	Shared Neighborhood Hits	849
SwissProt Accessions	Q6P4S6, Q641L5, Q66JZ5, Q6ZQ09, Q8K075, Q9CYD5	Gene names	Kiaa0999
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase KIAA0999 (EC 2.7.11.1).

K0999_HUMAN
NC score	0.857317 (rank : 109)	θ value	9.87957e-23 (rank : 117)
Query Neighborhood Hits	1959	Target Neighborhood Hits	899	Shared Neighborhood Hits	831
SwissProt Accessions	Q9Y2K2, Q59FY2, Q5M9N1, Q6P3R6, Q8IYM8, Q9HA50	Gene names	KIAA0999
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase KIAA0999 (EC 2.7.11.1).

SN1L2_HUMAN
NC score	0.857284 (rank : 110)	θ value	1.16704e-23 (rank : 105)
Query Neighborhood Hits	1959	Target Neighborhood Hits	964	Shared Neighborhood Hits	881
SwissProt Accessions	Q9H0K1, O94878, Q6AZE2, Q76N03, Q8NCV7, Q96CZ8	Gene names	SNF1LK2, KIAA0781, QIK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SNF1-like kinase 2 (EC 2.7.11.1) (Qin- induced kinase).

STK36_MOUSE
NC score	0.857278 (rank : 111)	θ value	1.29031e-22 (rank : 125)
Query Neighborhood Hits	1959	Target Neighborhood Hits	877	Shared Neighborhood Hits	829
SwissProt Accessions	Q69ZM6, Q6PDI0, Q80XQ6	Gene names	Stk36, Kiaa1278
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog).

KPCD3_MOUSE
NC score	0.857241 (rank : 112)	θ value	2.59989e-23 (rank : 109)
Query Neighborhood Hits	1959	Target Neighborhood Hits	901	Shared Neighborhood Hits	818
SwissProt Accessions	Q8K1Y2	Gene names	Prkd3, Prkcn
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (nPKC-nu).

PDPK1_HUMAN
NC score	0.857077 (rank : 113)	θ value	3.28887e-18 (rank : 223)
Query Neighborhood Hits	1959	Target Neighborhood Hits	851	Shared Neighborhood Hits	825
SwissProt Accessions	O15530	Gene names	PDPK1, PDK1
Domain Architecture
Description	3-phosphoinositide-dependent protein kinase 1 (EC 2.7.11.1) (hPDK1).

MARK2_MOUSE
NC score	0.856919 (rank : 114)	θ value	9.87957e-23 (rank : 119)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1018	Shared Neighborhood Hits	899
SwissProt Accessions	Q05512, Q6PDR4, Q8BR95	Gene names	Mark2, Emk
Domain Architecture
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1).

SN1L2_MOUSE
NC score	0.856900 (rank : 115)	θ value	3.07116e-24 (rank : 95)
Query Neighborhood Hits	1959	Target Neighborhood Hits	944	Shared Neighborhood Hits	869
SwissProt Accessions	Q8CFH6	Gene names	Snf1lk2, Sik2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SNF1-like kinase 2 (EC 2.7.11.1) (Salt-inducible kinase 2).

KPCD3_HUMAN
NC score	0.856749 (rank : 116)	θ value	7.56453e-23 (rank : 115)
Query Neighborhood Hits	1959	Target Neighborhood Hits	895	Shared Neighborhood Hits	819
SwissProt Accessions	O94806	Gene names	PRKD3, EPK2, PRKCN
Domain Architecture
Description	Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (nPKC-nu) (Protein kinase EPK2).

PDPK1_MOUSE
NC score	0.856713 (rank : 117)	θ value	1.13037e-18 (rank : 209)
Query Neighborhood Hits	1959	Target Neighborhood Hits	852	Shared Neighborhood Hits	825
SwissProt Accessions	Q9Z2A0, Q9R1D8, Q9R215	Gene names	Pdpk1, Pdk1
Domain Architecture
Description	3-phosphoinositide-dependent protein kinase 1 (EC 2.7.11.1) (mPDK1).

PRKY_HUMAN
NC score	0.856545 (rank : 118)	θ value	1.92812e-18 (rank : 217)
Query Neighborhood Hits	1959	Target Neighborhood Hits	844	Shared Neighborhood Hits	822
SwissProt Accessions	O43930, O15348, O15349	Gene names	PRKY
Domain Architecture
Description	Serine/threonine-protein kinase PRKY (EC 2.7.11.1).

MARK3_MOUSE
NC score	0.856019 (rank : 119)	θ value	2.87452e-22 (rank : 135)
Query Neighborhood Hits	1959	Target Neighborhood Hits	919	Shared Neighborhood Hits	846
SwissProt Accessions	Q03141, Q3TM40, Q3V1U3, Q8C6G9, Q8R375, Q9JKE4	Gene names	Mark3, Emk2, Mpk10
Domain Architecture	No domain graphic available
Description	MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (MPK-10) (ELKL motif kinase 2).

MKNK2_HUMAN
NC score	0.855656 (rank : 120)	θ value	1.058e-16 (rank : 284)
Query Neighborhood Hits	1959	Target Neighborhood Hits	821	Shared Neighborhood Hits	802
SwissProt Accessions	Q9HBH9, Q6GPI3, Q9HBH8, Q9UHR0, Q9Y2N6	Gene names	MKNK2, MNK2
Domain Architecture
Description	MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 2) (Mnk2).

SBK1_MOUSE
NC score	0.855590 (rank : 121)	θ value	2.28291e-11 (rank : 534)
Query Neighborhood Hits	1959	Target Neighborhood Hits	824	Shared Neighborhood Hits	806
SwissProt Accessions	Q8QZX0	Gene names	Sbk1, Sbk
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SBK1 (EC 2.7.11.1) (SH3-binding kinase 1).

MKNK2_MOUSE
NC score	0.855172 (rank : 122)	θ value	4.74913e-17 (rank : 271)
Query Neighborhood Hits	1959	Target Neighborhood Hits	819	Shared Neighborhood Hits	800
SwissProt Accessions	Q8CDB0, O08606, Q75PY0, Q9D893	Gene names	Mknk2, Mnk2
Domain Architecture
Description	MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 2) (Mnk2).

TSSK6_MOUSE
NC score	0.855084 (rank : 123)	θ value	1.058e-16 (rank : 288)
Query Neighborhood Hits	1959	Target Neighborhood Hits	824	Shared Neighborhood Hits	810
SwissProt Accessions	Q925K9, Q5RL09, Q8C625	Gene names	Tssk6, Sstk
Domain Architecture	No domain graphic available
Description	Testis-specific serine/threonine-protein kinase 6 (EC 2.7.11.1) (TSSK- 6) (Small serine/threonine kinase) (Serine/threonine-protein kinase SSTK).

MARK1_HUMAN
NC score	0.855044 (rank : 124)	θ value	8.93572e-24 (rank : 102)
Query Neighborhood Hits	1959	Target Neighborhood Hits	887	Shared Neighborhood Hits	836
SwissProt Accessions	Q9P0L2, Q5VTF9, Q5VTG0, Q96SW9, Q9P251	Gene names	MARK1, KIAA1477, MARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MARK1 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 1).

TSSK4_MOUSE
NC score	0.854840 (rank : 125)	θ value	1.16975e-15 (rank : 337)
Query Neighborhood Hits	1959	Target Neighborhood Hits	840	Shared Neighborhood Hits	822
SwissProt Accessions	Q9D411	Gene names	Tssk4
Domain Architecture	No domain graphic available
Description	Testis-specific serine/threonine-protein kinase 4 (EC 2.7.11.1) (TSSK- 4) (Testis-specific kinase 4) (TSK-4).

MARK1_MOUSE
NC score	0.854691 (rank : 126)	θ value	1.6852e-22 (rank : 126)
Query Neighborhood Hits	1959	Target Neighborhood Hits	886	Shared Neighborhood Hits	834
SwissProt Accessions	Q8VHJ5, Q69ZI7	Gene names	Mark1, Emk3, Kiaa1477
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MARK1 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 1) (ELKL motif serine/threonine-protein kinase 3).

PASK_HUMAN
NC score	0.854635 (rank : 127)	θ value	3.76295e-14 (rank : 423)
Query Neighborhood Hits	1959	Target Neighborhood Hits	857	Shared Neighborhood Hits	812
SwissProt Accessions	Q96RG2, Q86XH6, Q99763, Q9UFR7	Gene names	PASK, KIAA0135
Domain Architecture
Description	PAS domain-containing serine/threonine-protein kinase (EC 2.7.11.1) (PAS-kinase) (PASKIN) (hPASK).

SBK1_HUMAN
NC score	0.854352 (rank : 128)	θ value	1.74796e-11 (rank : 531)
Query Neighborhood Hits	1959	Target Neighborhood Hits	828	Shared Neighborhood Hits	807
SwissProt Accessions	Q52WX2	Gene names	SBK1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SBK1 (EC 2.7.11.1) (SH3-binding kinase 1).

KS6A2_MOUSE
NC score	0.854324 (rank : 129)	θ value	6.38894e-30 (rank : 40)
Query Neighborhood Hits	1959	Target Neighborhood Hits	858	Shared Neighborhood Hits	829
SwissProt Accessions	Q9WUT3, Q9D2C0	Gene names	Rps6ka2, Rsk3
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1) (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (Protein-tyrosine kinase Mpk-9) (MAP kinase- activated protein kinase 1c) (MAPKAPK1C).

TSSK6_HUMAN
NC score	0.854083 (rank : 130)	θ value	5.25075e-16 (rank : 321)
Query Neighborhood Hits	1959	Target Neighborhood Hits	824	Shared Neighborhood Hits	811
SwissProt Accessions	Q9BXA6, Q6ZMC4, Q96LJ4	Gene names	TSSK6, FKSG82, SSTK
Domain Architecture	No domain graphic available
Description	Testis-specific serine/threonine-protein kinase 6 (EC 2.7.11.1) (TSSK- 6) (Small serine/threonine kinase) (Serine/threonine-protein kinase SSTK).

KS6A2_HUMAN
NC score	0.853873 (rank : 131)	θ value	1.08979e-29 (rank : 44)
Query Neighborhood Hits	1959	Target Neighborhood Hits	857	Shared Neighborhood Hits	826
SwissProt Accessions	Q15349, Q15419, Q59GJ3, Q5TI68, Q96J38, Q9UJN5	Gene names	RPS6KA2, RSK3
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1) (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (MAP kinase-activated protein kinase 1c) (MAPKAPK1C).

KS6A1_MOUSE
NC score	0.853741 (rank : 132)	θ value	3.50572e-28 (rank : 55)
Query Neighborhood Hits	1959	Target Neighborhood Hits	850	Shared Neighborhood Hits	826
SwissProt Accessions	P18653	Gene names	Rps6ka1, Rsk1
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1) (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (p90S6K) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A).

KS6A6_HUMAN
NC score	0.853728 (rank : 133)	θ value	1.57365e-28 (rank : 52)
Query Neighborhood Hits	1959	Target Neighborhood Hits	853	Shared Neighborhood Hits	825
SwissProt Accessions	Q9UK32, Q8WX28, Q9H4S6	Gene names	RPS6KA6, RSK4
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-6 (EC 2.7.11.1) (S6K-alpha 6) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4).

CAMKV_MOUSE
NC score	0.853570 (rank : 134)	θ value	6.40375e-22 (rank : 138)
Query Neighborhood Hits	1959	Target Neighborhood Hits	848	Shared Neighborhood Hits	798
SwissProt Accessions	Q3UHL1, Q8VD20	Gene names	Camkv
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

TSSK1_MOUSE
NC score	0.853402 (rank : 135)	θ value	1.68911e-14 (rank : 405)
Query Neighborhood Hits	1959	Target Neighborhood Hits	835	Shared Neighborhood Hits	810
SwissProt Accessions	Q61241	Gene names	Tssk1, Stk22a
Domain Architecture
Description	Testis-specific serine/threonine-protein kinase 1 (EC 2.7.11.1) (TSSK- 1) (Testis-specific kinase 1) (TSK-1) (Serine/threonine-protein kinase 22A).

KS6A1_HUMAN
NC score	0.853103 (rank : 136)	θ value	1.02001e-27 (rank : 60)
Query Neighborhood Hits	1959	Target Neighborhood Hits	854	Shared Neighborhood Hits	827
SwissProt Accessions	Q15418, Q5SVM5, Q5SVM8, Q5SVM9, Q96C05, Q9BQK2	Gene names	RPS6KA1, RSK1
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1) (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (p90S6K) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A).

TSSK2_HUMAN
NC score	0.853027 (rank : 137)	θ value	3.40345e-15 (rank : 360)
Query Neighborhood Hits	1959	Target Neighborhood Hits	826	Shared Neighborhood Hits	808
SwissProt Accessions	Q96PF2, Q8IY55	Gene names	TSSK2, DGSG, SPOGA2, STK22B
Domain Architecture
Description	Testis-specific serine/threonine-protein kinase 2 (EC 2.7.11.1) (TSSK- 2) (Testis-specific kinase 2) (TSK-2) (Serine/threonine-protein kinase 22B) (DiGeorge syndrome protein G).

MKNK1_MOUSE
NC score	0.852888 (rank : 138)	θ value	2.27762e-19 (rank : 189)
Query Neighborhood Hits	1959	Target Neighborhood Hits	811	Shared Neighborhood Hits	790
SwissProt Accessions	O08605	Gene names	Mknk1, Mnk1
Domain Architecture
Description	MAP kinase-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (Mnk1).

TSSK4_HUMAN
NC score	0.852878 (rank : 139)	θ value	1.68911e-14 (rank : 406)
Query Neighborhood Hits	1959	Target Neighborhood Hits	836	Shared Neighborhood Hits	822
SwissProt Accessions	Q6SA08	Gene names	TSSK4, C14orf20, STK22E
Domain Architecture	No domain graphic available
Description	Testis-specific serine/threonine-protein kinase 4 (EC 2.7.11.1) (TSSK- 4) (Testis-specific kinase 4) (TSK-4) (Serine/threonine-protein kinase 22E).

NEK3_MOUSE
NC score	0.852834 (rank : 140)	θ value	4.58923e-20 (rank : 178)
Query Neighborhood Hits	1959	Target Neighborhood Hits	854	Shared Neighborhood Hits	826
SwissProt Accessions	Q9R0A5, Q9Z0X9	Gene names	Nek3
Domain Architecture
Description	Serine/threonine-protein kinase Nek3 (EC 2.7.11.1) (NimA-related protein kinase 3).

PAK6_HUMAN
NC score	0.852829 (rank : 141)	θ value	8.08199e-25 (rank : 84)
Query Neighborhood Hits	1959	Target Neighborhood Hits	915	Shared Neighborhood Hits	869
SwissProt Accessions	Q9NQU5	Gene names	PAK6, PAK5
Domain Architecture
Description	Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1) (p21-activated kinase 6) (PAK-6) (PAK-5).

KS6A3_MOUSE
NC score	0.852563 (rank : 142)	θ value	4.57862e-28 (rank : 58)
Query Neighborhood Hits	1959	Target Neighborhood Hits	860	Shared Neighborhood Hits	827
SwissProt Accessions	P18654, Q03140, Q8K3J8	Gene names	Rps6ka3, Rps6ka-rs1, Rsk2
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1) (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B).

KS6A3_HUMAN
NC score	0.852550 (rank : 143)	θ value	4.57862e-28 (rank : 57)
Query Neighborhood Hits	1959	Target Neighborhood Hits	859	Shared Neighborhood Hits	827
SwissProt Accessions	P51812, Q4VAP3, Q59H26, Q5JPK8, Q7Z3Z7	Gene names	RPS6KA3, ISPK1, RSK2
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1) (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B).

CAMKV_HUMAN
NC score	0.852500 (rank : 144)	θ value	6.40375e-22 (rank : 137)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1084	Shared Neighborhood Hits	897
SwissProt Accessions	Q8NCB2, Q6FIB8, Q8NBS8, Q8NC85, Q8NDU4, Q8WTT8, Q9BQC9, Q9H0Q5	Gene names	CAMKV
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

TSSK3_HUMAN
NC score	0.852180 (rank : 145)	θ value	2.13179e-17 (rank : 254)
Query Neighborhood Hits	1959	Target Neighborhood Hits	806	Shared Neighborhood Hits	789
SwissProt Accessions	Q96PN8	Gene names	TSSK3, SPOGA3, STK22C
Domain Architecture
Description	Testis-specific serine/threonine-protein kinase 3 (EC 2.7.11.1) (TSSK- 3) (Testis-specific kinase 3) (TSK-3) (Serine/threonine-protein kinase 22C).

TSSK3_MOUSE
NC score	0.851925 (rank : 146)	θ value	2.13179e-17 (rank : 255)
Query Neighborhood Hits	1959	Target Neighborhood Hits	806	Shared Neighborhood Hits	788
SwissProt Accessions	Q9D2E1, Q9JL98	Gene names	Tssk3, Stk22c, Stk22d
Domain Architecture
Description	Testis-specific serine/threonine-protein kinase 3 (EC 2.7.11.1) (TSSK- 3) (Testis-specific kinase 3) (TSK-3) (Serine/threonine-protein kinase 22C).

KAPCG_HUMAN
NC score	0.851827 (rank : 147)	θ value	1.86321e-21 (rank : 147)
Query Neighborhood Hits	1959	Target Neighborhood Hits	845	Shared Neighborhood Hits	822
SwissProt Accessions	P22612, O60850, Q86YI1	Gene names	PRKACG
Domain Architecture
Description	cAMP-dependent protein kinase, gamma-catalytic subunit (EC 2.7.11.11) (PKA C-gamma).

PRKX_MOUSE
NC score	0.851629 (rank : 148)	θ value	3.51386e-20 (rank : 175)
Query Neighborhood Hits	1959	Target Neighborhood Hits	846	Shared Neighborhood Hits	824
SwissProt Accessions	Q922R0, Q3UCD1, Q8BHD6, Q9QZ12	Gene names	Prkx, Pkare
Domain Architecture
Description	Serine/threonine-protein kinase PRKX (EC 2.7.11.1) (PKA-related protein kinase).

MARK3_HUMAN
NC score	0.851586 (rank : 149)	θ value	1.13037e-18 (rank : 208)
Query Neighborhood Hits	1959	Target Neighborhood Hits	893	Shared Neighborhood Hits	831
SwissProt Accessions	P27448, O60219, Q8TB41, Q8WX83, Q96RG1, Q9UMY9, Q9UN34	Gene names	MARK3, CTAK1
Domain Architecture
Description	MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (Cdc25C- associated protein kinase 1) (cTAK1) (C-TAK1) (Serine/threonine protein kinase p78) (Ser/Thr protein kinase PAR-1) (Protein kinase STK10).

TSSK1_HUMAN
NC score	0.851400 (rank : 150)	θ value	1.42992e-13 (rank : 448)
Query Neighborhood Hits	1959	Target Neighborhood Hits	840	Shared Neighborhood Hits	811
SwissProt Accessions	Q9BXA7	Gene names	TSSK1, SPOGA1, SPOGA4, STK22A, STK22D
Domain Architecture
Description	Testis-specific serine/threonine-protein kinase 1 (EC 2.7.11.1) (TSSK- 1) (Testis-specific kinase 1) (TSK-1) (Serine/threonine-protein kinase 22A).

PRKX_HUMAN
NC score	0.851367 (rank : 151)	θ value	5.99374e-20 (rank : 182)
Query Neighborhood Hits	1959	Target Neighborhood Hits	847	Shared Neighborhood Hits	822
SwissProt Accessions	P51817	Gene names	PRKX, PKX1
Domain Architecture
Description	Serine/threonine-protein kinase PRKX (EC 2.7.11.1) (Protein kinase PKX1).

PAK7_MOUSE
NC score	0.851229 (rank : 152)	θ value	1.62847e-25 (rank : 81)
Query Neighborhood Hits	1959	Target Neighborhood Hits	875	Shared Neighborhood Hits	836
SwissProt Accessions	Q8C015, Q3TQJ7, Q6RWS7	Gene names	Pak7, Pak5
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PAK 7 (EC 2.7.11.1) (p21-activated kinase 7) (PAK-7) (p21-activated kinase 5).

PAK7_HUMAN
NC score	0.851076 (rank : 153)	θ value	1.62847e-25 (rank : 80)
Query Neighborhood Hits	1959	Target Neighborhood Hits	875	Shared Neighborhood Hits	835
SwissProt Accessions	Q9P286, Q5W115, Q9BX09, Q9ULF6	Gene names	PAK7, KIAA1264, PAK5
Domain Architecture
Description	Serine/threonine-protein kinase PAK 7 (EC 2.7.11.1) (p21-activated kinase 7) (PAK-7) (PAK-5).

PAK4_HUMAN
NC score	0.850891 (rank : 154)	θ value	7.0802e-21 (rank : 154)
Query Neighborhood Hits	1959	Target Neighborhood Hits	924	Shared Neighborhood Hits	875
SwissProt Accessions	O96013, Q8N4E1, Q8NCH5, Q8NDE3, Q9BU33, Q9ULS8	Gene names	PAK4, KIAA1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

NEK3_HUMAN
NC score	0.850817 (rank : 155)	θ value	5.07402e-19 (rank : 197)
Query Neighborhood Hits	1959	Target Neighborhood Hits	865	Shared Neighborhood Hits	826
SwissProt Accessions	P51956, Q8WUN5	Gene names	NEK3
Domain Architecture
Description	Serine/threonine-protein kinase Nek3 (EC 2.7.11.1) (NimA-related protein kinase 3) (HSPK 36).

PAK4_MOUSE
NC score	0.850676 (rank : 156)	θ value	3.63628e-17 (rank : 265)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1098	Shared Neighborhood Hits	934
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

PAK2_HUMAN
NC score	0.850377 (rank : 157)	θ value	9.87957e-23 (rank : 120)
Query Neighborhood Hits	1959	Target Neighborhood Hits	862	Shared Neighborhood Hits	833
SwissProt Accessions	Q13177, Q13154	Gene names	PAK2
Domain Architecture
Description	Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (p21-activated kinase 2) (PAK-2) (PAK65) (Gamma-PAK) (S6/H4 kinase).

PAK2_MOUSE
NC score	0.850296 (rank : 158)	θ value	9.87957e-23 (rank : 121)
Query Neighborhood Hits	1959	Target Neighborhood Hits	858	Shared Neighborhood Hits	831
SwissProt Accessions	Q8CIN4	Gene names	Pak2
Domain Architecture
Description	Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (p21-activated kinase 2) (PAK-2).

KS6A5_HUMAN
NC score	0.850012 (rank : 159)	θ value	3.39556e-23 (rank : 111)
Query Neighborhood Hits	1959	Target Neighborhood Hits	855	Shared Neighborhood Hits	826
SwissProt Accessions	O75582, O95316, Q96AF7	Gene names	RPS6KA5, MSK1
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear mitogen- and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RSKL).

TSSK2_MOUSE
NC score	0.849177 (rank : 160)	θ value	1.58096e-12 (rank : 486)
Query Neighborhood Hits	1959	Target Neighborhood Hits	819	Shared Neighborhood Hits	798
SwissProt Accessions	O54863	Gene names	Tssk2, Stk22b
Domain Architecture
Description	Testis-specific serine/threonine-protein kinase 2 (EC 2.7.11.1) (TSSK- 2) (Testis-specific kinase 2) (TSK-2) (Serine/threonine-protein kinase 22B).

KAPCA_MOUSE
NC score	0.848917 (rank : 161)	θ value	1.92812e-18 (rank : 213)
Query Neighborhood Hits	1959	Target Neighborhood Hits	836	Shared Neighborhood Hits	820
SwissProt Accessions	P05132, Q9JID0	Gene names	Prkaca, Pkaca
Domain Architecture
Description	cAMP-dependent protein kinase, alpha-catalytic subunit (EC 2.7.11.11) (PKA C-alpha).

KAPCA_HUMAN
NC score	0.848639 (rank : 162)	θ value	1.13037e-18 (rank : 202)
Query Neighborhood Hits	1959	Target Neighborhood Hits	838	Shared Neighborhood Hits	820
SwissProt Accessions	P17612, Q9H2Y0, Q9NRB4, Q9NRH9	Gene names	PRKACA, PKACA
Domain Architecture
Description	cAMP-dependent protein kinase, alpha-catalytic subunit (EC 2.7.11.11) (PKA C-alpha).

PAK1_HUMAN
NC score	0.848475 (rank : 163)	θ value	2.20094e-22 (rank : 133)
Query Neighborhood Hits	1959	Target Neighborhood Hits	873	Shared Neighborhood Hits	841
SwissProt Accessions	Q13153, O75561, Q13567, Q32M53, Q32M54, Q86W79	Gene names	PAK1
Domain Architecture
Description	Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (p21-activated kinase 1) (PAK-1) (P65-PAK) (Alpha-PAK).

PAK3_HUMAN
NC score	0.848303 (rank : 164)	θ value	3.07116e-24 (rank : 93)
Query Neighborhood Hits	1959	Target Neighborhood Hits	887	Shared Neighborhood Hits	836
SwissProt Accessions	O75914, Q5JWX1, Q5JWX2, Q7Z2D6, Q7Z2E4, Q7Z3Z8, Q8WWK5, Q8WX23, Q9P0J8	Gene names	PAK3, OPHN3
Domain Architecture
Description	Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (p21-activated kinase 3) (PAK-3) (Beta-PAK) (Oligophrenin-3).

PAK3_MOUSE
NC score	0.848241 (rank : 165)	θ value	1.80048e-24 (rank : 91)
Query Neighborhood Hits	1959	Target Neighborhood Hits	874	Shared Neighborhood Hits	829
SwissProt Accessions	Q61036, O88645, Q8K1R5, Q8K1R6	Gene names	Pak3, Pak-3, Pakb, Stk4
Domain Architecture
Description	Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (p21-activated kinase 3) (PAK-3) (Beta-PAK) (CDC42/RAC effector kinase PAK-B).

PAK1_MOUSE
NC score	0.848095 (rank : 166)	θ value	8.36355e-22 (rank : 142)
Query Neighborhood Hits	1959	Target Neighborhood Hits	878	Shared Neighborhood Hits	844
SwissProt Accessions	O88643	Gene names	Pak1, Paka
Domain Architecture
Description	Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (p21-activated kinase 1) (PAK-1) (P65-PAK) (Alpha-PAK) (CDC42/RAC effector kinase PAK-A).

KAPCB_HUMAN
NC score	0.848046 (rank : 167)	θ value	1.13037e-18 (rank : 203)
Query Neighborhood Hits	1959	Target Neighborhood Hits	837	Shared Neighborhood Hits	821
SwissProt Accessions	P22694, Q59GC0, Q5BNE9, Q5BNF0, Q5BNF1, Q5BNF2, Q5BNF3, Q5CZ92, Q5T1K3, Q7Z3M1, Q8IYR5, Q8IZQ0	Gene names	PRKACB
Domain Architecture
Description	cAMP-dependent protein kinase, beta-catalytic subunit (EC 2.7.11.11) (PKA C-beta).

KAPCB_MOUSE
NC score	0.847804 (rank : 168)	θ value	3.28887e-18 (rank : 221)
Query Neighborhood Hits	1959	Target Neighborhood Hits	836	Shared Neighborhood Hits	821
SwissProt Accessions	P68181, P05206, Q3TQH5, Q3UDD0, Q3UTH5	Gene names	Prkacb, Pkacb
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase, beta-catalytic subunit (EC 2.7.11.11) (PKA C-beta).

ULK4_MOUSE
NC score	0.847643 (rank : 169)	θ value	3.40345e-15 (rank : 361)
Query Neighborhood Hits	1959	Target Neighborhood Hits	793	Shared Neighborhood Hits	766
SwissProt Accessions	Q3V129, Q2VP87, Q32LZ6, Q8BLS0, Q8C8Z5, Q9D4H6	Gene names	Ulk4
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK4 (EC 2.7.11.1) (Unc-51-like kinase 4).

M3K1_MOUSE
NC score	0.847127 (rank : 170)	θ value	6.41864e-14 (rank : 433)
Query Neighborhood Hits	1959	Target Neighborhood Hits	952	Shared Neighborhood Hits	857
SwissProt Accessions	P53349, Q60831, Q9R0U3, Q9R256	Gene names	Map3k1, Mekk, Mekk1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1).

M3K2_MOUSE
NC score	0.846977 (rank : 171)	θ value	1.058e-16 (rank : 283)
Query Neighborhood Hits	1959	Target Neighborhood Hits	846	Shared Neighborhood Hits	821
SwissProt Accessions	Q61083	Gene names	Map3k2, Mekk2
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2).

NEK2_HUMAN
NC score	0.846962 (rank : 172)	θ value	1.38178e-16 (rank : 291)
Query Neighborhood Hits	1959	Target Neighborhood Hits	908	Shared Neighborhood Hits	808
SwissProt Accessions	P51955, Q53FD6, Q5VXZ1, Q6NZX8, Q7Z634, Q86XH2, Q96QN9	Gene names	NEK2, NLK1
Domain Architecture
Description	Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (NimA-related protein kinase 2) (NimA-like protein kinase 1) (HSPK 21).

NEK2_MOUSE
NC score	0.846937 (rank : 173)	θ value	5.25075e-16 (rank : 318)
Query Neighborhood Hits	1959	Target Neighborhood Hits	876	Shared Neighborhood Hits	806
SwissProt Accessions	O35942, O35959	Gene names	Nek2
Domain Architecture
Description	Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (NimA-related protein kinase 2).

M3K3_MOUSE
NC score	0.846903 (rank : 174)	θ value	5.07402e-19 (rank : 196)
Query Neighborhood Hits	1959	Target Neighborhood Hits	876	Shared Neighborhood Hits	834
SwissProt Accessions	Q61084	Gene names	Map3k3, Mekk3
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3).

ST32A_MOUSE
NC score	0.846829 (rank : 175)	θ value	1.92812e-18 (rank : 219)
Query Neighborhood Hits	1959	Target Neighborhood Hits	833	Shared Neighborhood Hits	813
SwissProt Accessions	Q8BGW6, Q7TPQ4	Gene names	Stk32a
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 32A (EC 2.7.11.1).

M3K3_HUMAN
NC score	0.846748 (rank : 176)	θ value	2.97466e-19 (rank : 191)
Query Neighborhood Hits	1959	Target Neighborhood Hits	885	Shared Neighborhood Hits	835
SwissProt Accessions	Q99759	Gene names	MAP3K3, MAPKKK3, MEKK3
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3).

KS6B1_MOUSE
NC score	0.846556 (rank : 177)	θ value	1.13037e-18 (rank : 207)
Query Neighborhood Hits	1959	Target Neighborhood Hits	849	Shared Neighborhood Hits	821
SwissProt Accessions	Q8BSK8, Q8CHX0	Gene names	Rps6kb1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1) (Ribosomal protein S6 kinase I) (S6K) (S6K1) (70 kDa ribosomal protein S6 kinase 1) (p70 S6 kinase alpha) (p70(S6K)-alpha) (p70-S6K) (P70S6K).

KS6B1_HUMAN
NC score	0.846548 (rank : 178)	θ value	1.13037e-18 (rank : 206)
Query Neighborhood Hits	1959	Target Neighborhood Hits	850	Shared Neighborhood Hits	821
SwissProt Accessions	P23443	Gene names	RPS6KB1
Domain Architecture
Description	Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1) (Ribosomal protein S6 kinase I) (S6K) (S6K1) (70 kDa ribosomal protein S6 kinase 1) (p70 S6 kinase alpha) (p70(S6K)-alpha) (p70-S6K) (P70S6K) (p70-alpha).

KS6B2_HUMAN
NC score	0.846540 (rank : 179)	θ value	1.92812e-18 (rank : 214)
Query Neighborhood Hits	1959	Target Neighborhood Hits	858	Shared Neighborhood Hits	834
SwissProt Accessions	Q9UBS0, O94809, Q9UEC1	Gene names	RPS6KB2, STK14B
Domain Architecture
Description	Ribosomal protein S6 kinase beta-2 (EC 2.7.11.1) (S6K2) (70 kDa ribosomal protein S6 kinase 2) (p70-S6KB) (p70 ribosomal S6 kinase beta) (p70 S6Kbeta) (p70 S6 kinase beta) (S6K-beta) (p70-beta) (S6 kinase-related kinase) (SRK) (Serine/threonine-protein kinase 14 beta).

KS6A4_MOUSE
NC score	0.846431 (rank : 180)	θ value	1.2077e-20 (rank : 160)
Query Neighborhood Hits	1959	Target Neighborhood Hits	866	Shared Neighborhood Hits	826
SwissProt Accessions	Q9Z2B9, Q91X18	Gene names	Rps6ka4, Msk2
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-4 (EC 2.7.11.1) (Nuclear mitogen- and stress-activated protein kinase 2) (90 kDa ribosomal protein S6 kinase 4) (RSK-like protein kinase) (RLSK).

KS6A4_HUMAN
NC score	0.846369 (rank : 181)	θ value	2.06002e-20 (rank : 166)
Query Neighborhood Hits	1959	Target Neighborhood Hits	868	Shared Neighborhood Hits	829
SwissProt Accessions	O75676, O75585, Q53ES8	Gene names	RPS6KA4, MSK2
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-4 (EC 2.7.11.1) (Nuclear mitogen- and stress-activated protein kinase 2) (90 kDa ribosomal protein S6 kinase 4) (Ribosomal protein kinase B) (RSKB).

ST32A_HUMAN
NC score	0.846321 (rank : 182)	θ value	7.32683e-18 (rank : 235)
Query Neighborhood Hits	1959	Target Neighborhood Hits	834	Shared Neighborhood Hits	816
SwissProt Accessions	Q8WU08	Gene names	STK32A
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 32A (EC 2.7.11.1) (YANK1).

AKT3_HUMAN
NC score	0.846258 (rank : 183)	θ value	1.80048e-24 (rank : 89)
Query Neighborhood Hits	1959	Target Neighborhood Hits	872	Shared Neighborhood Hits	822
SwissProt Accessions	Q9Y243, Q96QV3, Q9UFP5	Gene names	AKT3
Domain Architecture
Description	RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) (STK-2).

NEK4_MOUSE
NC score	0.846255 (rank : 184)	θ value	6.85773e-16 (rank : 324)
Query Neighborhood Hits	1959	Target Neighborhood Hits	899	Shared Neighborhood Hits	836
SwissProt Accessions	Q9Z1J2, O35673, Q9R1J1	Gene names	Nek4, Stk2
Domain Architecture
Description	Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2).

AKT3_MOUSE
NC score	0.846238 (rank : 185)	θ value	1.80048e-24 (rank : 90)
Query Neighborhood Hits	1959	Target Neighborhood Hits	872	Shared Neighborhood Hits	822
SwissProt Accessions	Q9WUA6	Gene names	Akt3
Domain Architecture
Description	RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma).

ST32C_MOUSE
NC score	0.845562 (rank : 186)	θ value	1.02238e-19 (rank : 186)
Query Neighborhood Hits	1959	Target Neighborhood Hits	824	Shared Neighborhood Hits	809
SwissProt Accessions	Q8QZV4, Q9JJG4	Gene names	Stk32c, Pkek
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 32C (EC 2.7.11.1).

M3K2_HUMAN
NC score	0.845479 (rank : 187)	θ value	4.02038e-16 (rank : 311)
Query Neighborhood Hits	1959	Target Neighborhood Hits	849	Shared Neighborhood Hits	825
SwissProt Accessions	Q9Y2U5, Q53QL9, Q53S75, Q59GZ6, Q8NC32, Q9NYK3	Gene names	MAP3K2, MAPKKK2, MEKK2
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2).

IKKA_MOUSE
NC score	0.845398 (rank : 188)	θ value	1.92812e-18 (rank : 212)
Query Neighborhood Hits	1959	Target Neighborhood Hits	867	Shared Neighborhood Hits	820
SwissProt Accessions	Q60680, Q80VU2, Q9D2X3	Gene names	Chuk, Ikka
Domain Architecture
Description	Inhibitor of nuclear factor kappa-B kinase alpha subunit (EC 2.7.11.10) (I kappa-B kinase alpha) (IkBKA) (IKK-alpha) (IKK-A) (IkappaB kinase) (I-kappa-B kinase 1) (IKK1) (Conserved helix-loop- helix ubiquitous kinase) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA).

AKT2_HUMAN
NC score	0.845329 (rank : 189)	θ value	4.43474e-23 (rank : 113)
Query Neighborhood Hits	1959	Target Neighborhood Hits	878	Shared Neighborhood Hits	819
SwissProt Accessions	P31751, Q68GC0	Gene names	AKT2
Domain Architecture
Description	RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta).

KS6B2_MOUSE
NC score	0.845148 (rank : 190)	θ value	6.62687e-19 (rank : 198)
Query Neighborhood Hits	1959	Target Neighborhood Hits	871	Shared Neighborhood Hits	835
SwissProt Accessions	Q9Z1M4	Gene names	Rps6kb2
Domain Architecture
Description	Ribosomal protein S6 kinase beta-2 (EC 2.7.11.1) (S6K-beta 2) (70 kDa ribosomal protein S6 kinase 2) (p70-S6KB) (p70 ribosomal S6 kinase beta) (p70 S6Kbeta) (S6K2).

NEK1_HUMAN
NC score	0.845097 (rank : 191)	θ value	2.20605e-14 (rank : 413)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1129	Shared Neighborhood Hits	862
SwissProt Accessions	Q96PY6, Q9Y594	Gene names	NEK1, KIAA1901
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1) (NY-REN-55 antigen).

NEK4_HUMAN
NC score	0.844855 (rank : 192)	θ value	8.95645e-16 (rank : 332)
Query Neighborhood Hits	1959	Target Neighborhood Hits	883	Shared Neighborhood Hits	828
SwissProt Accessions	P51957	Gene names	NEK4, STK2
Domain Architecture
Description	Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2) (Serine/threonine-protein kinase NRK2).

MAPK5_MOUSE
NC score	0.844793 (rank : 193)	θ value	5.60996e-18 (rank : 229)
Query Neighborhood Hits	1959	Target Neighborhood Hits	799	Shared Neighborhood Hits	779
SwissProt Accessions	O54992, Q6QME4, Q6QME5, Q6QME6, Q6QME7	Gene names	Mapkapk5
Domain Architecture	No domain graphic available
Description	MAP kinase-activated protein kinase 5 (EC 2.7.11.1) (MAPK-activated protein kinase 5) (MAPKAP kinase 5).

AKT2_MOUSE
NC score	0.844763 (rank : 194)	θ value	2.59989e-23 (rank : 108)
Query Neighborhood Hits	1959	Target Neighborhood Hits	875	Shared Neighborhood Hits	819
SwissProt Accessions	Q60823	Gene names	Akt2
Domain Architecture
Description	RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta).

ST32B_MOUSE
NC score	0.844552 (rank : 195)	θ value	8.95645e-16 (rank : 334)
Query Neighborhood Hits	1959	Target Neighborhood Hits	828	Shared Neighborhood Hits	813
SwissProt Accessions	Q9JJX8, Q7TMD3, Q8C4E0	Gene names	Stk32b, Stk32
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 32B (EC 2.7.11.1).

SGK1_HUMAN
NC score	0.844155 (rank : 196)	θ value	1.80466e-16 (rank : 300)
Query Neighborhood Hits	1959	Target Neighborhood Hits	848	Shared Neighborhood Hits	823
SwissProt Accessions	O00141, Q5TCN3, Q9UN56	Gene names	SGK, SGK1
Domain Architecture
Description	Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 1).

NEK1_MOUSE
NC score	0.844151 (rank : 197)	θ value	4.02038e-16 (rank : 313)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1311	Shared Neighborhood Hits	901
SwissProt Accessions	P51954	Gene names	Nek1
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1).

ST32B_HUMAN
NC score	0.844130 (rank : 198)	θ value	8.10077e-17 (rank : 281)
Query Neighborhood Hits	1959	Target Neighborhood Hits	830	Shared Neighborhood Hits	814
SwissProt Accessions	Q9NY57, Q6UXH3, Q8IY14	Gene names	STK32B
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 32B (EC 2.7.11.1) (YANK2).

M3K6_HUMAN
NC score	0.843996 (rank : 199)	θ value	4.58923e-20 (rank : 177)
Query Neighborhood Hits	1959	Target Neighborhood Hits	889	Shared Neighborhood Hits	837
SwissProt Accessions	O95382	Gene names	MAP3K6, MAPKKK6
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 6 (EC 2.7.11.25).

SGK1_MOUSE
NC score	0.843988 (rank : 200)	θ value	3.07829e-16 (rank : 308)
Query Neighborhood Hits	1959	Target Neighborhood Hits	848	Shared Neighborhood Hits	822
SwissProt Accessions	Q9WVC6	Gene names	Sgk, Sgk1
Domain Architecture
Description	Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 1).

SGK2_HUMAN
NC score	0.843982 (rank : 201)	θ value	7.32683e-18 (rank : 234)
Query Neighborhood Hits	1959	Target Neighborhood Hits	840	Shared Neighborhood Hits	817
SwissProt Accessions	Q9HBY8, Q9UKG6	Gene names	SGK2
Domain Architecture
Description	Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 2).

ST32C_HUMAN
NC score	0.843856 (rank : 202)	θ value	1.2077e-20 (rank : 161)
Query Neighborhood Hits	1959	Target Neighborhood Hits	832	Shared Neighborhood Hits	813
SwissProt Accessions	Q86UX6, Q5T0Q5, Q86UE1	Gene names	STK32C
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 32C (EC 2.7.11.1) (PKE) (YANK3).

SGK2_MOUSE
NC score	0.843725 (rank : 203)	θ value	9.56915e-18 (rank : 242)
Query Neighborhood Hits	1959	Target Neighborhood Hits	833	Shared Neighborhood Hits	815
SwissProt Accessions	Q9QZS5, Q8R0P6	Gene names	Sgk2
Domain Architecture
Description	Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 2).

MAPK5_HUMAN
NC score	0.843556 (rank : 204)	θ value	4.29542e-18 (rank : 226)
Query Neighborhood Hits	1959	Target Neighborhood Hits	795	Shared Neighborhood Hits	775
SwissProt Accessions	Q8IW41, O60491, Q86X46, Q9BVX9, Q9UG86	Gene names	MAPKAPK5, PRAK
Domain Architecture	No domain graphic available
Description	MAP kinase-activated protein kinase 5 (EC 2.7.11.1) (MAPK-activated protein kinase 5) (MAPKAP kinase 5) (p38-regulated/activated protein kinase).

IKKA_HUMAN
NC score	0.843396 (rank : 205)	θ value	7.32683e-18 (rank : 232)
Query Neighborhood Hits	1959	Target Neighborhood Hits	863	Shared Neighborhood Hits	819
SwissProt Accessions	O15111, O14666, Q13132, Q92467	Gene names	CHUK, IKKA
Domain Architecture
Description	Inhibitor of nuclear factor kappa-B kinase alpha subunit (EC 2.7.11.10) (I kappa-B kinase alpha) (IkBKA) (IKK-alpha) (IKK-A) (IkappaB kinase) (I-kappa-B kinase 1) (IKK1) (Conserved helix-loop- helix ubiquitous kinase) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA).

KS6A5_MOUSE
NC score	0.843367 (rank : 206)	θ value	2.06002e-20 (rank : 167)
Query Neighborhood Hits	1959	Target Neighborhood Hits	854	Shared Neighborhood Hits	823
SwissProt Accessions	Q8C050, Q8CI92	Gene names	Rps6ka5, Msk1
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear mitogen- and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RLSK).

NEK6_HUMAN
NC score	0.842326 (rank : 207)	θ value	3.52202e-12 (rank : 504)
Query Neighborhood Hits	1959	Target Neighborhood Hits	848	Shared Neighborhood Hits	825
SwissProt Accessions	Q9HC98, Q96E83, Q9ULX2	Gene names	NEK6
Domain Architecture
Description	Serine/threonine-protein kinase Nek6 (EC 2.7.11.1) (NimA-related protein kinase 6) (Protein kinase SID6-1512).

NEK6_MOUSE
NC score	0.842179 (rank : 208)	θ value	3.52202e-12 (rank : 505)
Query Neighborhood Hits	1959	Target Neighborhood Hits	851	Shared Neighborhood Hits	825
SwissProt Accessions	Q9ES70, Q3TCE9, Q8C6E6, Q9D0E2, Q9DBI8	Gene names	Nek6
Domain Architecture
Description	Serine/threonine-protein kinase Nek6 (EC 2.7.11.1) (NimA-related protein kinase 6).

RK_MOUSE
NC score	0.841819 (rank : 209)	θ value	2.7842e-17 (rank : 259)
Query Neighborhood Hits	1959	Target Neighborhood Hits	829	Shared Neighborhood Hits	812
SwissProt Accessions	Q9WVL4	Gene names	Grk1, Rhok
Domain Architecture
Description	Rhodopsin kinase precursor (EC 2.7.11.14) (RK) (G protein-coupled receptor kinase 1).

IKKE_HUMAN
NC score	0.841767 (rank : 210)	θ value	2.60593e-15 (rank : 353)
Query Neighborhood Hits	1959	Target Neighborhood Hits	837	Shared Neighborhood Hits	798
SwissProt Accessions	Q14164	Gene names	IKBKE, IKKE, IKKI, KIAA0151
Domain Architecture
Description	Inhibitor of nuclear factor kappa-B kinase epsilon subunit (EC 2.7.11.10) (I kappa-B kinase epsilon) (IkBKE) (IKK-epsilon) (IKK- E) (Inducible I kappa-B kinase) (IKK-i).

AKT1_HUMAN
NC score	0.841513 (rank : 211)	θ value	2.20094e-22 (rank : 128)
Query Neighborhood Hits	1959	Target Neighborhood Hits	885	Shared Neighborhood Hits	818
SwissProt Accessions	P31749, Q9BWB6	Gene names	AKT1, PKB, RAC
Domain Architecture
Description	RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-alpha) (Protein kinase B) (PKB) (C-AKT).

NEK11_MOUSE
NC score	0.841243 (rank : 212)	θ value	4.02038e-16 (rank : 312)
Query Neighborhood Hits	1959	Target Neighborhood Hits	875	Shared Neighborhood Hits	822
SwissProt Accessions	Q8C0Q4, Q8BLS6, Q8BW62	Gene names	Nek11
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11).

AKT1_MOUSE
NC score	0.841234 (rank : 213)	θ value	2.20094e-22 (rank : 129)
Query Neighborhood Hits	1959	Target Neighborhood Hits	878	Shared Neighborhood Hits	818
SwissProt Accessions	P31750, Q62274	Gene names	Akt1, Akt, Rac
Domain Architecture
Description	RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-alpha) (AKT1 kinase) (Protein kinase B) (PKB) (C-AKT) (Thymoma viral proto- oncogene).

IKKB_HUMAN
NC score	0.841226 (rank : 214)	θ value	3.07829e-16 (rank : 305)
Query Neighborhood Hits	1959	Target Neighborhood Hits	980	Shared Neighborhood Hits	826
SwissProt Accessions	O14920, O75327	Gene names	IKBKB, IKKB
Domain Architecture
Description	Inhibitor of nuclear factor kappa B kinase subunit beta (EC 2.7.11.10) (I-kappa-B-kinase beta) (IkBKB) (IKK-beta) (IKK-B) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB).

IKKB_MOUSE
NC score	0.840826 (rank : 215)	θ value	4.74913e-17 (rank : 270)
Query Neighborhood Hits	1959	Target Neighborhood Hits	984	Shared Neighborhood Hits	820
SwissProt Accessions	O88351, Q9R1J6	Gene names	Ikbkb, Ikkb
Domain Architecture
Description	Inhibitor of nuclear factor kappa B kinase subunit beta (EC 2.7.11.10) (I-kappa-B-kinase beta) (IkBKB) (IKK-beta) (IKK-B) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB).

M3K4_HUMAN
NC score	0.840704 (rank : 216)	θ value	2.69671e-12 (rank : 500)
Query Neighborhood Hits	1959	Target Neighborhood Hits	911	Shared Neighborhood Hits	836
SwissProt Accessions	Q9Y6R4, Q92612	Gene names	MAP3K4, KIAA0213, MAPKKK4, MEKK4, MTK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4) (MAP three kinase 1).

IKKE_MOUSE
NC score	0.840481 (rank : 217)	θ value	4.44505e-15 (rank : 365)
Query Neighborhood Hits	1959	Target Neighborhood Hits	848	Shared Neighborhood Hits	801
SwissProt Accessions	Q9R0T8	Gene names	Ikbke, Ikke, Ikki
Domain Architecture
Description	Inhibitor of nuclear factor kappa-B kinase epsilon subunit (EC 2.7.11.10) (I kappa-B kinase epsilon) (IkBKE) (IKK-epsilon) (IKK- E) (Inducible I kappa-B kinase) (IKK-i).

M3K5_MOUSE
NC score	0.840384 (rank : 218)	θ value	3.63628e-17 (rank : 264)
Query Neighborhood Hits	1959	Target Neighborhood Hits	867	Shared Neighborhood Hits	820
SwissProt Accessions	O35099	Gene names	Map3k5, Ask1, Mekk5
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5) (Apoptosis signal- regulating kinase 1) (ASK-1).

M3K5_HUMAN
NC score	0.840278 (rank : 219)	θ value	3.63628e-17 (rank : 263)
Query Neighborhood Hits	1959	Target Neighborhood Hits	868	Shared Neighborhood Hits	819
SwissProt Accessions	Q99683, Q5THN3, Q99461	Gene names	MAP3K5, ASK1, MAPKKK5, MEKK5
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5) (Apoptosis signal- regulating kinase 1) (ASK-1).

M3K4_MOUSE
NC score	0.839747 (rank : 220)	θ value	1.2105e-12 (rank : 476)
Query Neighborhood Hits	1959	Target Neighborhood Hits	924	Shared Neighborhood Hits	836
SwissProt Accessions	O08648, O08649, O70124	Gene names	Map3k4, Mekk4
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4).

NEK7_HUMAN
NC score	0.839724 (rank : 221)	θ value	2.43908e-13 (rank : 454)
Query Neighborhood Hits	1959	Target Neighborhood Hits	846	Shared Neighborhood Hits	824
SwissProt Accessions	Q8TDX7	Gene names	NEK7
Domain Architecture
Description	Serine/threonine-protein kinase Nek7 (EC 2.7.11.1) (NimA-related protein kinase 7).

NEK7_MOUSE
NC score	0.839707 (rank : 222)	θ value	3.18553e-13 (rank : 458)
Query Neighborhood Hits	1959	Target Neighborhood Hits	847	Shared Neighborhood Hits	825
SwissProt Accessions	Q9ES74, Q3UEV7	Gene names	Nek7
Domain Architecture
Description	Serine/threonine-protein kinase Nek7 (EC 2.7.11.1) (NimA-related protein kinase 7).

TBK1_HUMAN
NC score	0.839429 (rank : 223)	θ value	1.29331e-14 (rank : 395)
Query Neighborhood Hits	1959	Target Neighborhood Hits	861	Shared Neighborhood Hits	791
SwissProt Accessions	Q9UHD2, Q8IYV3, Q9NUJ5	Gene names	TBK1, NAK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (TANK-binding kinase 1) (T2K) (NF-kappa-B-activating kinase).

M3K15_HUMAN
NC score	0.839346 (rank : 224)	θ value	8.10077e-17 (rank : 277)
Query Neighborhood Hits	1959	Target Neighborhood Hits	914	Shared Neighborhood Hits	827
SwissProt Accessions	Q6ZN16, Q5JPR4, Q6ZMV3	Gene names	MAP3K15
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 15 (EC 2.7.11.25) (MAPK/ERK kinase kinase 15) (MEK kinase 15) (MEKK 15).

E2AK2_MOUSE
NC score	0.839167 (rank : 225)	θ value	2.69671e-12 (rank : 498)
Query Neighborhood Hits	1959	Target Neighborhood Hits	864	Shared Neighborhood Hits	824
SwissProt Accessions	Q03963, Q61742, Q62026	Gene names	Eif2ak2, Pkr, Prkr, Tik
Domain Architecture
Description	Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Interferon-inducible RNA-dependent protein kinase) (Protein kinase RNA-activated) (PKR) (p68 kinase) (P1/eIF-2A protein kinase) (Serine/threonine-protein kinase TIK).

TBK1_MOUSE
NC score	0.839088 (rank : 226)	θ value	1.68911e-14 (rank : 404)
Query Neighborhood Hits	1959	Target Neighborhood Hits	893	Shared Neighborhood Hits	792
SwissProt Accessions	Q9WUN2, Q9CT90, Q9DC03	Gene names	Tbk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (TANK-binding kinase 1) (T2K).

RK_HUMAN
NC score	0.838829 (rank : 227)	θ value	5.25075e-16 (rank : 320)
Query Neighborhood Hits	1959	Target Neighborhood Hits	835	Shared Neighborhood Hits	814
SwissProt Accessions	Q15835	Gene names	GRK1, RHOK
Domain Architecture
Description	Rhodopsin kinase precursor (EC 2.7.11.14) (RK) (G protein-coupled receptor kinase 1).

TTK_HUMAN
NC score	0.838449 (rank : 228)	θ value	1.38178e-16 (rank : 293)
Query Neighborhood Hits	1959	Target Neighborhood Hits	816	Shared Neighborhood Hits	775
SwissProt Accessions	P33981	Gene names	TTK, MPS1L1
Domain Architecture
Description	Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein kinase) (PYT).

SGK3_MOUSE
NC score	0.838244 (rank : 229)	θ value	1.47631e-18 (rank : 211)
Query Neighborhood Hits	1959	Target Neighborhood Hits	882	Shared Neighborhood Hits	817
SwissProt Accessions	Q9ERE3, Q3UAY2	Gene names	Sgk3, Cisk, Sgkl
Domain Architecture
Description	Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid- regulated kinase-like) (Cytokine-independent survival kinase).

M3K14_HUMAN
NC score	0.838077 (rank : 230)	θ value	6.00763e-12 (rank : 515)
Query Neighborhood Hits	1959	Target Neighborhood Hits	887	Shared Neighborhood Hits	835
SwissProt Accessions	Q99558, Q8IYN1	Gene names	MAP3K14, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF- kappa beta-inducing kinase) (Serine/threonine-protein kinase NIK) (HsNIK).

SGK3_HUMAN
NC score	0.837854 (rank : 231)	θ value	1.24977e-17 (rank : 245)
Query Neighborhood Hits	1959	Target Neighborhood Hits	877	Shared Neighborhood Hits	817
SwissProt Accessions	Q96BR1, Q9P1Q7, Q9UKG5	Gene names	SGK3, SGKL
Domain Architecture
Description	Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid- regulated kinase-like).

NEK11_HUMAN
NC score	0.837792 (rank : 232)	θ value	9.90251e-15 (rank : 387)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1043	Shared Neighborhood Hits	837
SwissProt Accessions	Q8NG66, Q5JPC0, Q8NG65, Q8TBY1, Q9H5F4	Gene names	NEK11
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11).

CDKL3_MOUSE
NC score	0.837787 (rank : 233)	θ value	9.90251e-15 (rank : 381)
Query Neighborhood Hits	1959	Target Neighborhood Hits	857	Shared Neighborhood Hits	824
SwissProt Accessions	Q8BLF2, Q5M6W2, Q8BKR2, Q8BL49, Q8BVE0, Q8K134	Gene names	Cdkl3
Domain Architecture	No domain graphic available
Description	Cyclin-dependent kinase-like 3 (EC 2.7.11.22).

PIM2_MOUSE
NC score	0.837786 (rank : 234)	θ value	1.2105e-12 (rank : 479)
Query Neighborhood Hits	1959	Target Neighborhood Hits	809	Shared Neighborhood Hits	792
SwissProt Accessions	Q62070, Q62071, Q62072	Gene names	Pim2, Pim-2
Domain Architecture
Description	Serine/threonine-protein kinase Pim-2 (EC 2.7.11.1).

KGP1A_HUMAN
NC score	0.837293 (rank : 235)	θ value	2.69047e-20 (rank : 171)
Query Neighborhood Hits	1959	Target Neighborhood Hits	901	Shared Neighborhood Hits	822
SwissProt Accessions	Q13976	Gene names	PRKG1, PRKGR1A
Domain Architecture
Description	cGMP-dependent protein kinase 1, alpha isozyme (EC 2.7.11.12) (CGK 1 alpha) (cGKI-alpha).

KGP2_HUMAN
NC score	0.837226 (rank : 236)	θ value	1.63225e-17 (rank : 247)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1023	Shared Neighborhood Hits	832
SwissProt Accessions	Q13237, O00125, O60916	Gene names	PRKG2, PRKGR2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

TTK_MOUSE
NC score	0.837170 (rank : 237)	θ value	4.02038e-16 (rank : 315)
Query Neighborhood Hits	1959	Target Neighborhood Hits	803	Shared Neighborhood Hits	758
SwissProt Accessions	P35761	Gene names	Ttk, Esk
Domain Architecture
Description	Dual specificity protein kinase TTK (EC 2.7.12.1) (ESK) (PYT).

NEK8_MOUSE
NC score	0.837093 (rank : 238)	θ value	5.8054e-15 (rank : 372)
Query Neighborhood Hits	1959	Target Neighborhood Hits	872	Shared Neighborhood Hits	824
SwissProt Accessions	Q91ZR4, Q3U498, Q9D685	Gene names	Nek8, Jck
Domain Architecture
Description	Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never in mitosis A-related kinase 8) (NimA-related protein kinase 8).

CDKL3_HUMAN
NC score	0.837073 (rank : 239)	θ value	4.44505e-15 (rank : 364)
Query Neighborhood Hits	1959	Target Neighborhood Hits	853	Shared Neighborhood Hits	823
SwissProt Accessions	Q8IVW4, Q9P114	Gene names	CDKL3, NKIAMRE
Domain Architecture	No domain graphic available
Description	Cyclin-dependent kinase-like 3 (EC 2.7.11.22) (Serine/threonine protein kinase NKIAMRE).

NEK8_HUMAN
NC score	0.837072 (rank : 240)	θ value	5.8054e-15 (rank : 371)
Query Neighborhood Hits	1959	Target Neighborhood Hits	872	Shared Neighborhood Hits	825
SwissProt Accessions	Q86SG6, Q2M1S6, Q8NDH1	Gene names	NEK8, JCK, NEK12A
Domain Architecture
Description	Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never in mitosis A-related kinase 8) (NimA-related protein kinase 8) (NIMA-related kinase 12a).

KGP1B_MOUSE
NC score	0.836970 (rank : 241)	θ value	2.69047e-20 (rank : 173)
Query Neighborhood Hits	1959	Target Neighborhood Hits	922	Shared Neighborhood Hits	825
SwissProt Accessions	Q9Z0Z0	Gene names	Prkg1, Prkg1b, Prkgr1b
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KGP1B_HUMAN
NC score	0.836903 (rank : 242)	θ value	2.69047e-20 (rank : 172)
Query Neighborhood Hits	1959	Target Neighborhood Hits	921	Shared Neighborhood Hits	825
SwissProt Accessions	P14619	Gene names	PRKG1, PRKG1B, PRKGR1B
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KGP2_MOUSE
NC score	0.836881 (rank : 243)	θ value	1.24977e-17 (rank : 244)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1029	Shared Neighborhood Hits	831
SwissProt Accessions	Q61410	Gene names	Prkg2, Prkgr2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

PIM2_HUMAN
NC score	0.836784 (rank : 244)	θ value	1.133e-10 (rank : 560)
Query Neighborhood Hits	1959	Target Neighborhood Hits	808	Shared Neighborhood Hits	792
SwissProt Accessions	Q9P1W9, Q99739	Gene names	PIM2
Domain Architecture
Description	Serine/threonine-protein kinase Pim-2 (EC 2.7.11.1) (Pim-2h).

M3K14_MOUSE
NC score	0.836561 (rank : 245)	θ value	2.69671e-12 (rank : 499)
Query Neighborhood Hits	1959	Target Neighborhood Hits	889	Shared Neighborhood Hits	824
SwissProt Accessions	Q9WUL6	Gene names	Map3k14, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF- kappa beta-inducing kinase) (Serine/threonine-protein kinase NIK).

PIM1_HUMAN
NC score	0.835469 (rank : 246)	θ value	7.84624e-12 (rank : 519)
Query Neighborhood Hits	1959	Target Neighborhood Hits	797	Shared Neighborhood Hits	782
SwissProt Accessions	P11309, Q38RT9, Q96RG3	Gene names	PIM1
Domain Architecture
Description	Proto-oncogene serine/threonine-protein kinase Pim-1 (EC 2.7.11.1).

PKN2_MOUSE
NC score	0.835323 (rank : 247)	θ value	3.63628e-17 (rank : 267)
Query Neighborhood Hits	1959	Target Neighborhood Hits	899	Shared Neighborhood Hits	820
SwissProt Accessions	Q8BWW9, Q80WS2, Q8BJL7	Gene names	Pkn2, Prkcl2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein kinase C- like 2) (Protein-kinase C-related kinase 2).

CDKL5_HUMAN
NC score	0.835261 (rank : 248)	θ value	1.38178e-16 (rank : 289)
Query Neighborhood Hits	1959	Target Neighborhood Hits	967	Shared Neighborhood Hits	867
SwissProt Accessions	O76039, Q14198, Q5H985, Q9UJL6	Gene names	CDKL5, STK9
Domain Architecture
Description	Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine- protein kinase 9).

STK3_MOUSE
NC score	0.835209 (rank : 249)	θ value	1.74391e-19 (rank : 188)
Query Neighborhood Hits	1959	Target Neighborhood Hits	869	Shared Neighborhood Hits	821
SwissProt Accessions	Q9JI10, Q60877, Q80UG4, Q8CI58	Gene names	Stk3, Mess1, Mst2
Domain Architecture
Description	Serine/threonine-protein kinase 3 (EC 2.7.11.1) (STE20-like kinase MST2) (MST-2) (Mammalian STE20-like protein kinase 2).

YSK4_HUMAN
NC score	0.835074 (rank : 250)	θ value	1.29331e-14 (rank : 397)
Query Neighborhood Hits	1959	Target Neighborhood Hits	921	Shared Neighborhood Hits	830
SwissProt Accessions	Q56UN5, Q56UN1, Q56UN2, Q56UN3, Q56UN4, Q8N4E9, Q9H5T2	Gene names	YSK4, RCK
Domain Architecture	No domain graphic available
Description	SPS1/STE20-related protein kinase YSK4 (EC 2.7.11.1) (Regulated in COPD, protein kinase).

PKN2_HUMAN
NC score	0.835042 (rank : 251)	θ value	3.63628e-17 (rank : 266)
Query Neighborhood Hits	1959	Target Neighborhood Hits	892	Shared Neighborhood Hits	819
SwissProt Accessions	Q16513, Q9H1W4	Gene names	PKN2, PRK2, PRKCL2
Domain Architecture
Description	Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein kinase C- like 2) (Protein-kinase C-related kinase 2).

STK4_MOUSE
NC score	0.834955 (rank : 252)	θ value	2.27762e-19 (rank : 190)
Query Neighborhood Hits	1959	Target Neighborhood Hits	873	Shared Neighborhood Hits	824
SwissProt Accessions	Q9JI11	Gene names	Stk4, Mst1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 4 (EC 2.7.11.1) (STE20-like kinase MST1) (MST-1) (Mammalian STE20-like protein kinase 1).

STK4_HUMAN
NC score	0.834935 (rank : 253)	θ value	4.58923e-20 (rank : 181)
Query Neighborhood Hits	1959	Target Neighborhood Hits	870	Shared Neighborhood Hits	824
SwissProt Accessions	Q13043, Q15802, Q4G156, Q5H982, Q6PD60, Q9BR32, Q9NTZ4	Gene names	STK4, MST1
Domain Architecture
Description	Serine/threonine-protein kinase 4 (EC 2.7.11.1) (STE20-like kinase MST1) (MST-1) (Mammalian STE20-like protein kinase 1) (Serine/threonine-protein kinase Krs-2).

GRK5_MOUSE
NC score	0.834911 (rank : 254)	θ value	1.80466e-16 (rank : 297)
Query Neighborhood Hits	1959	Target Neighborhood Hits	823	Shared Neighborhood Hits	802
SwissProt Accessions	Q8VEB1, O70292, O70297	Gene names	Grk5, Gprk5
Domain Architecture
Description	G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK5).

STK3_HUMAN
NC score	0.834886 (rank : 255)	θ value	4.58923e-20 (rank : 180)
Query Neighborhood Hits	1959	Target Neighborhood Hits	861	Shared Neighborhood Hits	821
SwissProt Accessions	Q13188, Q15445, Q15801, Q96FM6	Gene names	STK3, MST2
Domain Architecture
Description	Serine/threonine-protein kinase 3 (EC 2.7.11.1) (STE20-like kinase MST2) (MST-2) (Mammalian STE20-like protein kinase 2) (Serine/threonine-protein kinase Krs-1).

PIM3_HUMAN
NC score	0.834836 (rank : 256)	θ value	1.33837e-11 (rank : 528)
Query Neighborhood Hits	1959	Target Neighborhood Hits	789	Shared Neighborhood Hits	774
SwissProt Accessions	Q86V86, Q68BM2	Gene names	PIM3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase Pim-3 (EC 2.7.11.1).

CDKL1_MOUSE
NC score	0.834744 (rank : 257)	θ value	7.0802e-21 (rank : 153)
Query Neighborhood Hits	1959	Target Neighborhood Hits	829	Shared Neighborhood Hits	812
SwissProt Accessions	Q8CEQ0	Gene names	Cdkl1
Domain Architecture	No domain graphic available
Description	Cyclin-dependent kinase-like 1 (EC 2.7.11.22).

GRK6_HUMAN
NC score	0.834598 (rank : 258)	θ value	8.95645e-16 (rank : 330)
Query Neighborhood Hits	1959	Target Neighborhood Hits	823	Shared Neighborhood Hits	808
SwissProt Accessions	P43250, O60541, Q13652	Gene names	GRK6, GPRK6
Domain Architecture
Description	G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK6).

GRK5_HUMAN
NC score	0.834594 (rank : 259)	θ value	1.80466e-16 (rank : 296)
Query Neighborhood Hits	1959	Target Neighborhood Hits	819	Shared Neighborhood Hits	802
SwissProt Accessions	P34947	Gene names	GRK5, GPRK5
Domain Architecture
Description	G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK5).

PKN3_MOUSE
NC score	0.834545 (rank : 260)	θ value	1.13037e-18 (rank : 210)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1009	Shared Neighborhood Hits	877
SwissProt Accessions	Q8K045	Gene names	Pkn3, Pknbeta
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

PKN3_HUMAN
NC score	0.834491 (rank : 261)	θ value	6.85773e-16 (rank : 326)
Query Neighborhood Hits	1959	Target Neighborhood Hits	893	Shared Neighborhood Hits	831
SwissProt Accessions	Q6P5Z2, Q9UM03	Gene names	PKN3, PKNBETA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

PIM1_MOUSE
NC score	0.834329 (rank : 262)	θ value	6.64225e-11 (rank : 552)
Query Neighborhood Hits	1959	Target Neighborhood Hits	787	Shared Neighborhood Hits	768
SwissProt Accessions	P06803	Gene names	Pim1, Pim-1
Domain Architecture	No domain graphic available
Description	Proto-oncogene serine/threonine-protein kinase Pim-1 (EC 2.7.11.1).

CDKL1_HUMAN
NC score	0.834224 (rank : 263)	θ value	4.58923e-20 (rank : 176)
Query Neighborhood Hits	1959	Target Neighborhood Hits	830	Shared Neighborhood Hits	813
SwissProt Accessions	Q00532, Q6QUA0	Gene names	CDKL1
Domain Architecture
Description	Cyclin-dependent kinase-like 1 (EC 2.7.11.22) (Serine/threonine- protein kinase KKIALRE) (Protein kinase p42 KKIALRE).

MAST3_HUMAN
NC score	0.834067 (rank : 264)	θ value	1.68911e-14 (rank : 401)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1128	Shared Neighborhood Hits	930
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

GRK6_MOUSE
NC score	0.833777 (rank : 265)	θ value	1.99529e-15 (rank : 343)
Query Neighborhood Hits	1959	Target Neighborhood Hits	820	Shared Neighborhood Hits	807
SwissProt Accessions	O70293, O70294, O70295	Gene names	Grk6, Gprk6
Domain Architecture
Description	G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK6).

CDKL4_MOUSE
NC score	0.833536 (rank : 266)	θ value	2.69047e-20 (rank : 170)
Query Neighborhood Hits	1959	Target Neighborhood Hits	833	Shared Neighborhood Hits	814
SwissProt Accessions	Q3TZA2	Gene names	Cdkl4
Domain Architecture	No domain graphic available
Description	Cyclin-dependent kinase-like 4 (EC 2.7.11.22).

PKN1_MOUSE
NC score	0.833210 (rank : 267)	θ value	3.28887e-18 (rank : 225)
Query Neighborhood Hits	1959	Target Neighborhood Hits	888	Shared Neighborhood Hits	821
SwissProt Accessions	P70268, Q7TST2	Gene names	Pkn1, Pkn, Prk1, Prkcl1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protein kinase C- like 1) (Protein-kinase C-related kinase 1) (Protein kinase C-like PKN) (Serine-threonine protein kinase N).

M3K8_MOUSE
NC score	0.832988 (rank : 268)	θ value	1.47974e-10 (rank : 564)
Query Neighborhood Hits	1959	Target Neighborhood Hits	815	Shared Neighborhood Hits	791
SwissProt Accessions	Q07174	Gene names	Map3k8, Cot
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 8 (EC 2.7.11.25) (COT proto-oncogene serine/threonine-protein kinase) (C-COT) (Cancer Osaka thyroid oncogene).

PIM3_MOUSE
NC score	0.832928 (rank : 269)	θ value	3.89403e-11 (rank : 539)
Query Neighborhood Hits	1959	Target Neighborhood Hits	783	Shared Neighborhood Hits	769
SwissProt Accessions	P58750	Gene names	Pim3
Domain Architecture
Description	Serine/threonine-protein kinase Pim-3 (EC 2.7.11.1).

PKN1_HUMAN
NC score	0.832917 (rank : 270)	θ value	3.28887e-18 (rank : 224)
Query Neighborhood Hits	1959	Target Neighborhood Hits	886	Shared Neighborhood Hits	828
SwissProt Accessions	Q16512, Q15143, Q8IUV5	Gene names	PKN1, PKN, PRK1, PRKCL1
Domain Architecture
Description	Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protein kinase C- like 1) (Protein-kinase C-related kinase 1) (Protein kinase C-like PKN) (Serine-threonine protein kinase N) (Protein kinase PKN-alpha).

M3K8_HUMAN
NC score	0.832707 (rank : 271)	θ value	2.52405e-10 (rank : 570)
Query Neighborhood Hits	1959	Target Neighborhood Hits	807	Shared Neighborhood Hits	790
SwissProt Accessions	P41279, Q14275, Q9HC81	Gene names	MAP3K8, COT
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 8 (EC 2.7.11.25) (COT proto-oncogene serine/threonine-protein kinase) (C-COT) (Cancer Osaka thyroid oncogene).

PDK1L_HUMAN
NC score	0.832525 (rank : 272)	θ value	2.36244e-08 (rank : 645)
Query Neighborhood Hits	1959	Target Neighborhood Hits	821	Shared Neighborhood Hits	801
SwissProt Accessions	Q8N165, Q5T2I0, Q8NDB3	Gene names	PDIK1L, CLIK1L
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PDIK1L (EC 2.7.11.1) (PDLIM1- interacting kinase 1-like).

PDK1L_MOUSE
NC score	0.832404 (rank : 273)	θ value	2.36244e-08 (rank : 646)
Query Neighborhood Hits	1959	Target Neighborhood Hits	821	Shared Neighborhood Hits	802
SwissProt Accessions	Q8QZR7, Q3URF0, Q8BKB3	Gene names	Pdik1l
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PDIK1L (EC 2.7.11.1) (PDLIM1- interacting kinase 1-like).

KPCT_MOUSE
NC score	0.832400 (rank : 274)	θ value	2.20605e-14 (rank : 408)
Query Neighborhood Hits	1959	Target Neighborhood Hits	895	Shared Neighborhood Hits	825
SwissProt Accessions	Q02111	Gene names	Prkcq, Pkcq
Domain Architecture
Description	Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta).

KPCT_HUMAN
NC score	0.832227 (rank : 275)	θ value	4.59992e-12 (rank : 506)
Query Neighborhood Hits	1959	Target Neighborhood Hits	897	Shared Neighborhood Hits	827
SwissProt Accessions	Q04759, Q3MJF1, Q64FY5, Q9H508, Q9H549	Gene names	PRKCQ, PRKCT
Domain Architecture
Description	Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta).

KPCI_MOUSE
NC score	0.831792 (rank : 276)	θ value	6.20254e-17 (rank : 273)
Query Neighborhood Hits	1959	Target Neighborhood Hits	888	Shared Neighborhood Hits	825
SwissProt Accessions	Q62074	Gene names	Prkci, Pkcl
Domain Architecture
Description	Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota) (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota).

KPCI_HUMAN
NC score	0.831373 (rank : 277)	θ value	8.95645e-16 (rank : 331)
Query Neighborhood Hits	1959	Target Neighborhood Hits	885	Shared Neighborhood Hits	826
SwissProt Accessions	P41743, Q8WW06	Gene names	PRKCI, DXS1179E
Domain Architecture
Description	Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota) (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) (PRKC-lambda/iota).

STK24_HUMAN
NC score	0.831369 (rank : 278)	θ value	1.92812e-18 (rank : 220)
Query Neighborhood Hits	1959	Target Neighborhood Hits	853	Shared Neighborhood Hits	826
SwissProt Accessions	Q9Y6E0, O14840	Gene names	STK24, MST3, STK3
Domain Architecture
Description	Serine/threonine-protein kinase 24 (EC 2.7.11.1) (STE20-like kinase MST3) (MST-3) (Mammalian STE20-like protein kinase 3).

CDKL4_HUMAN
NC score	0.831211 (rank : 279)	θ value	1.5773e-20 (rank : 162)
Query Neighborhood Hits	1959	Target Neighborhood Hits	828	Shared Neighborhood Hits	810
SwissProt Accessions	Q5MAI5	Gene names	CDKL4
Domain Architecture	No domain graphic available
Description	Cyclin-dependent kinase-like 4 (EC 2.7.11.22).

MAST2_MOUSE
NC score	0.831139 (rank : 280)	θ value	6.85773e-16 (rank : 323)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1110	Shared Neighborhood Hits	899
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

CDKL2_MOUSE
NC score	0.831007 (rank : 281)	θ value	3.07829e-16 (rank : 304)
Query Neighborhood Hits	1959	Target Neighborhood Hits	854	Shared Neighborhood Hits	820
SwissProt Accessions	Q9QUK0, Q3UL60, Q3V3X7, Q9QYI1, Q9QYI2	Gene names	Cdkl2, Kkiamre, Kkm
Domain Architecture	No domain graphic available
Description	Cyclin-dependent kinase-like 2 (EC 2.7.11.22) (Serine/threonine- protein kinase KKIAMRE).

GRK4_HUMAN
NC score	0.830785 (rank : 282)	θ value	1.68911e-14 (rank : 398)
Query Neighborhood Hits	1959	Target Neighborhood Hits	822	Shared Neighborhood Hits	803
SwissProt Accessions	P32298, O00641, O00642, Q13293, Q13294, Q13295, Q14453, Q14725, Q15313, Q15314, Q15315, Q15316	Gene names	GRK4, GPRK2L, GPRK4
Domain Architecture
Description	G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK4) (ITI1).

OXSR1_HUMAN
NC score	0.830574 (rank : 283)	θ value	7.09661e-13 (rank : 471)
Query Neighborhood Hits	1959	Target Neighborhood Hits	874	Shared Neighborhood Hits	833
SwissProt Accessions	O95747, Q3LR53, Q7Z501, Q9UPQ1	Gene names	OXSR1, KIAA1101, OSR1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress- responsive 1 protein).

STK24_MOUSE
NC score	0.830565 (rank : 284)	θ value	4.74913e-17 (rank : 272)
Query Neighborhood Hits	1959	Target Neighborhood Hits	856	Shared Neighborhood Hits	827
SwissProt Accessions	Q99KH8	Gene names	Stk24
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 24 (EC 2.7.11.1).

CDKL2_HUMAN
NC score	0.830451 (rank : 285)	θ value	1.99529e-15 (rank : 342)
Query Neighborhood Hits	1959	Target Neighborhood Hits	838	Shared Neighborhood Hits	815
SwissProt Accessions	Q92772	Gene names	CDKL2
Domain Architecture	No domain graphic available
Description	Cyclin-dependent kinase-like 2 (EC 2.7.11.22) (Serine/threonine- protein kinase KKIAMRE) (Protein kinase p56 KKIAMRE).

MAST4_HUMAN
NC score	0.830275 (rank : 286)	θ value	1.52774e-15 (rank : 338)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1804	Shared Neighborhood Hits	1149
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

MAST2_HUMAN
NC score	0.830173 (rank : 287)	θ value	6.85773e-16 (rank : 322)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1189	Shared Neighborhood Hits	931
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

OXSR1_MOUSE
NC score	0.830100 (rank : 288)	θ value	1.58096e-12 (rank : 483)
Query Neighborhood Hits	1959	Target Neighborhood Hits	865	Shared Neighborhood Hits	827
SwissProt Accessions	Q6P9R2, Q8BVZ9, Q8C0B9	Gene names	Oxsr1, Osr1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress- responsive 1 protein).

MST4_MOUSE
NC score	0.830099 (rank : 289)	θ value	4.44505e-15 (rank : 367)
Query Neighborhood Hits	1959	Target Neighborhood Hits	860	Shared Neighborhood Hits	822
SwissProt Accessions	Q99JT2	Gene names	Mst4
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MST4 (EC 2.7.11.1) (STE20-like kinase MST4) (MST-4) (Mammalian STE20-like protein kinase 4).

MST4_HUMAN
NC score	0.830044 (rank : 290)	θ value	4.44505e-15 (rank : 366)
Query Neighborhood Hits	1959	Target Neighborhood Hits	852	Shared Neighborhood Hits	822
SwissProt Accessions	Q9P289, Q3ZB77, Q9BXC4	Gene names	MST4, MASK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MST4 (EC 2.7.11.1) (STE20-like kinase MST4) (MST-4) (Mammalian STE20-like protein kinase 4) (Serine/threonine-protein kinase MASK) (Mst3 and SOK1-related kinase).

STK39_MOUSE
NC score	0.828908 (rank : 291)	θ value	3.89403e-11 (rank : 542)
Query Neighborhood Hits	1959	Target Neighborhood Hits	915	Shared Neighborhood Hits	841
SwissProt Accessions	Q9Z1W9, Q80W13	Gene names	Stk39, Spak
Domain Architecture
Description	STE20/SPS1-related proline-alanine-rich protein kinase (EC 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39).

KPCL_MOUSE
NC score	0.828725 (rank : 292)	θ value	3.07829e-16 (rank : 306)
Query Neighborhood Hits	1959	Target Neighborhood Hits	891	Shared Neighborhood Hits	809
SwissProt Accessions	P23298	Gene names	Prkch, Pkch
Domain Architecture
Description	Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta) (PKC-L).

E2AK2_HUMAN
NC score	0.828692 (rank : 293)	θ value	1.25267e-09 (rank : 595)
Query Neighborhood Hits	1959	Target Neighborhood Hits	856	Shared Neighborhood Hits	814
SwissProt Accessions	P19525	Gene names	EIF2AK2, PKR, PRKR
Domain Architecture
Description	Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Interferon-inducible RNA-dependent protein kinase) (Protein kinase RNA-activated) (PKR) (p68 kinase) (P1/eIF-2A protein kinase).

GRK4_MOUSE
NC score	0.828653 (rank : 294)	θ value	1.80466e-16 (rank : 295)
Query Neighborhood Hits	1959	Target Neighborhood Hits	808	Shared Neighborhood Hits	797
SwissProt Accessions	O70291	Gene names	Grk4, Gprk2l
Domain Architecture
Description	G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK4).

GRK7_HUMAN
NC score	0.828540 (rank : 295)	θ value	4.0297e-08 (rank : 658)
Query Neighborhood Hits	1959	Target Neighborhood Hits	820	Shared Neighborhood Hits	809
SwissProt Accessions	Q8WTQ7	Gene names	GRK7, GPRK7
Domain Architecture
Description	G protein-coupled receptor kinase 7 precursor (EC 2.7.11.16) (G protein-coupled receptor kinase GRK7).

STK39_HUMAN
NC score	0.828395 (rank : 296)	θ value	3.89403e-11 (rank : 541)
Query Neighborhood Hits	1959	Target Neighborhood Hits	882	Shared Neighborhood Hits	832
SwissProt Accessions	Q9UEW8, O14774, Q9UER4	Gene names	STK39, SPAK
Domain Architecture
Description	STE20/SPS1-related proline-alanine-rich protein kinase (EC 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39) (DCHT).

STK25_HUMAN
NC score	0.828273 (rank : 297)	θ value	5.43371e-13 (rank : 469)
Query Neighborhood Hits	1959	Target Neighborhood Hits	853	Shared Neighborhood Hits	822
SwissProt Accessions	O00506, Q15522, Q5BJF1	Gene names	STK25, SOK1, YSK1
Domain Architecture
Description	Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Sterile 20/oxidant stress-response kinase 1) (Ste20/oxidant stress response kinase 1) (SOK-1) (Ste20-like kinase).

MP2K2_HUMAN
NC score	0.828052 (rank : 298)	θ value	8.38298e-14 (rank : 439)
Query Neighborhood Hits	1959	Target Neighborhood Hits	830	Shared Neighborhood Hits	815
SwissProt Accessions	P36507	Gene names	MAP2K2, MEK2, MKK2, PRKMK2
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 2 (EC 2.7.12.2) (MAP kinase kinase 2) (MAPKK 2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK2).

STK35_HUMAN
NC score	0.828013 (rank : 299)	θ value	6.43352e-06 (rank : 777)
Query Neighborhood Hits	1959	Target Neighborhood Hits	825	Shared Neighborhood Hits	804
SwissProt Accessions	Q8TDR2, Q5T3R1, Q5T3R2, Q96AB4, Q9BZ06	Gene names	STK35, CLIK1, PDIK1
Domain Architecture
Description	Serine/threonine-protein kinase 35 (EC 2.7.11.1) (CLP-36-interacting kinase) (Clik1) (PDLIM1-interacting kinase 1).

STK25_MOUSE
NC score	0.827895 (rank : 300)	θ value	2.43908e-13 (rank : 457)
Query Neighborhood Hits	1959	Target Neighborhood Hits	851	Shared Neighborhood Hits	822
SwissProt Accessions	Q9Z2W1	Gene names	Stk25, Sok1
Domain Architecture
Description	Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Sterile 20/oxidant stress-response kinase 1) (Ste20/oxidant stress response kinase 1) (SOK-1) (Ste20-like kinase).

MAST1_HUMAN
NC score	0.827636 (rank : 301)	θ value	9.90251e-15 (rank : 384)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1146	Shared Neighborhood Hits	918
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MAST1_MOUSE
NC score	0.827315 (rank : 302)	θ value	9.90251e-15 (rank : 385)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1123	Shared Neighborhood Hits	906
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

KPCD_HUMAN
NC score	0.827125 (rank : 303)	θ value	4.91457e-14 (rank : 427)
Query Neighborhood Hits	1959	Target Neighborhood Hits	900	Shared Neighborhood Hits	821
SwissProt Accessions	Q05655, Q15144	Gene names	PRKCD
Domain Architecture
Description	Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta).

KPCZ_MOUSE
NC score	0.826998 (rank : 304)	θ value	1.99529e-15 (rank : 345)
Query Neighborhood Hits	1959	Target Neighborhood Hits	882	Shared Neighborhood Hits	818
SwissProt Accessions	Q02956	Gene names	Prkcz, Pkcz
Domain Architecture
Description	Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta).

PMYT1_MOUSE
NC score	0.826959 (rank : 305)	θ value	2.28291e-11 (rank : 533)
Query Neighborhood Hits	1959	Target Neighborhood Hits	910	Shared Neighborhood Hits	850
SwissProt Accessions	Q9ESG9, Q8R3L4	Gene names	Pkmyt1, Myt1
Domain Architecture	No domain graphic available
Description	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase).

KPCZ_HUMAN
NC score	0.826957 (rank : 306)	θ value	1.99529e-15 (rank : 344)
Query Neighborhood Hits	1959	Target Neighborhood Hits	884	Shared Neighborhood Hits	818
SwissProt Accessions	Q05513, Q15207, Q5SYT5, Q969S4	Gene names	PRKCZ, PKC2
Domain Architecture
Description	Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta).

KPCL_HUMAN
NC score	0.826863 (rank : 307)	θ value	2.43908e-13 (rank : 453)
Query Neighborhood Hits	1959	Target Neighborhood Hits	887	Shared Neighborhood Hits	809
SwissProt Accessions	P24723, Q16246	Gene names	PRKCH, PKCL
Domain Architecture
Description	Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta) (PKC-L).

MP2K2_MOUSE
NC score	0.826679 (rank : 308)	θ value	2.20605e-14 (rank : 412)
Query Neighborhood Hits	1959	Target Neighborhood Hits	828	Shared Neighborhood Hits	814
SwissProt Accessions	Q63932	Gene names	Map2k2, Mek2, Mkk2, Prkmk2
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 2 (EC 2.7.12.2) (MAP kinase kinase 2) (MAPKK 2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK2).

CDC2_HUMAN
NC score	0.826630 (rank : 309)	θ value	3.63628e-17 (rank : 260)
Query Neighborhood Hits	1959	Target Neighborhood Hits	842	Shared Neighborhood Hits	820
SwissProt Accessions	P06493, O60764	Gene names	CDC2
Domain Architecture
Description	Cell division control protein 2 homolog (EC 2.7.11.22) (EC 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1).

KPCE_MOUSE
NC score	0.826464 (rank : 310)	θ value	2.88119e-14 (rank : 415)
Query Neighborhood Hits	1959	Target Neighborhood Hits	906	Shared Neighborhood Hits	819
SwissProt Accessions	P16054	Gene names	Prkce, Pkce, Pkcea
Domain Architecture
Description	Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon).

KPCE_HUMAN
NC score	0.826435 (rank : 311)	θ value	9.90251e-15 (rank : 383)
Query Neighborhood Hits	1959	Target Neighborhood Hits	906	Shared Neighborhood Hits	818
SwissProt Accessions	Q02156, Q53SL4, Q53SM5, Q9UE81	Gene names	PRKCE, PKCE
Domain Architecture
Description	Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon).

M4K3_HUMAN
NC score	0.826349 (rank : 312)	θ value	7.58209e-15 (rank : 374)
Query Neighborhood Hits	1959	Target Neighborhood Hits	857	Shared Neighborhood Hits	822
SwissProt Accessions	Q8IVH8, Q8IVH7, Q9UDM5, Q9Y6R5	Gene names	MAP4K3
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3) (Germinal center kinase-related protein kinase) (GLK).

MP2K1_HUMAN
NC score	0.826284 (rank : 313)	θ value	3.52202e-12 (rank : 502)
Query Neighborhood Hits	1959	Target Neighborhood Hits	826	Shared Neighborhood Hits	812
SwissProt Accessions	Q02750	Gene names	MAP2K1, MEK1, PRKMK1
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 1 (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1).

MP2K1_MOUSE
NC score	0.826183 (rank : 314)	θ value	3.52202e-12 (rank : 503)
Query Neighborhood Hits	1959	Target Neighborhood Hits	826	Shared Neighborhood Hits	812
SwissProt Accessions	P31938	Gene names	Map2k1, Mek1, Prkmk1
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 1 (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1).

KPCD_MOUSE
NC score	0.825961 (rank : 315)	θ value	8.38298e-14 (rank : 436)
Query Neighborhood Hits	1959	Target Neighborhood Hits	888	Shared Neighborhood Hits	818
SwissProt Accessions	P28867, Q91V85, Q9Z333	Gene names	Prkcd, Pkcd
Domain Architecture
Description	Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta).

M4K1_HUMAN
NC score	0.825876 (rank : 316)	θ value	1.99529e-15 (rank : 347)
Query Neighborhood Hits	1959	Target Neighborhood Hits	884	Shared Neighborhood Hits	829
SwissProt Accessions	Q92918	Gene names	MAP4K1, HPK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1) (Hematopoietic progenitor kinase).

CDK3_MOUSE
NC score	0.825776 (rank : 317)	θ value	2.43908e-13 (rank : 452)
Query Neighborhood Hits	1959	Target Neighborhood Hits	829	Shared Neighborhood Hits	814
SwissProt Accessions	Q80YP0	Gene names	Cdk3
Domain Architecture	No domain graphic available
Description	Truncated cell division protein kinase 3 homolog.

CDC2_MOUSE
NC score	0.825687 (rank : 318)	θ value	4.02038e-16 (rank : 310)
Query Neighborhood Hits	1959	Target Neighborhood Hits	838	Shared Neighborhood Hits	819
SwissProt Accessions	P11440, P70337, Q3TI12	Gene names	Cdc2, Cdc2a
Domain Architecture
Description	Cell division control protein 2 homolog (EC 2.7.11.22) (EC 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1).

MP2K5_MOUSE
NC score	0.825343 (rank : 319)	θ value	1.2105e-12 (rank : 477)
Query Neighborhood Hits	1959	Target Neighborhood Hits	840	Shared Neighborhood Hits	820
SwissProt Accessions	Q9WVS7, Q8CFM3, Q8K360, Q9D222	Gene names	Map2k5, Mek5, Mkk5, Prkmk5
Domain Architecture	No domain graphic available
Description	Dual specificity mitogen-activated protein kinase kinase 5 (EC 2.7.12.2) (MAP kinase kinase 5) (MAPKK 5) (MAPK/ERK kinase 5).

NEK9_HUMAN
NC score	0.825320 (rank : 320)	θ value	4.59992e-12 (rank : 509)
Query Neighborhood Hits	1959	Target Neighborhood Hits	900	Shared Neighborhood Hits	833
SwissProt Accessions	Q8TD19, Q52LK6, Q8NCN0, Q8TCY4, Q9UPI4, Q9Y6S4, Q9Y6S5, Q9Y6S6	Gene names	NEK9, KIAA1995, NEK8, NERCC
Domain Architecture
Description	Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (NimA-related protein kinase 9) (Never in mitosis A-related kinase 9) (Nercc1 kinase) (NIMA-related kinase 8) (Nek8).

CSKP_MOUSE
NC score	0.825228 (rank : 321)	θ value	6.82597e-32 (rank : 35)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1027	Shared Neighborhood Hits	817
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

ST38L_HUMAN
NC score	0.825063 (rank : 322)	θ value	9.24701e-21 (rank : 158)
Query Neighborhood Hits	1959	Target Neighborhood Hits	824	Shared Neighborhood Hits	790
SwissProt Accessions	Q9Y2H1, Q8TBX7	Gene names	STK38L, KIAA0965, NDR2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 38-like (EC 2.7.11.1) (NDR2 protein kinase) (Nuclear Dbf2-related kinase 2).

NEK9_MOUSE
NC score	0.824643 (rank : 323)	θ value	4.59992e-12 (rank : 510)
Query Neighborhood Hits	1959	Target Neighborhood Hits	890	Shared Neighborhood Hits	829
SwissProt Accessions	Q8K1R7, Q8R3P1	Gene names	Nek9, Nercc
Domain Architecture
Description	Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (NimA-related protein kinase 9) (Never in mitosis A-related kinase 9).

ARBK1_HUMAN
NC score	0.824392 (rank : 324)	θ value	3.40345e-15 (rank : 358)
Query Neighborhood Hits	1959	Target Neighborhood Hits	859	Shared Neighborhood Hits	813
SwissProt Accessions	P25098, Q13837	Gene names	ADRBK1, BARK, BARK1, GRK2
Domain Architecture
Description	Beta-adrenergic receptor kinase 1 (EC 2.7.11.15) (Beta-ARK-1) (G- protein coupled receptor kinase 2).

TLK1_HUMAN
NC score	0.824248 (rank : 325)	θ value	2.0648e-12 (rank : 492)
Query Neighborhood Hits	1959	Target Neighborhood Hits	967	Shared Neighborhood Hits	771
SwissProt Accessions	Q9UKI8, Q14150, Q8N591, Q9NYH2, Q9Y4F6	Gene names	TLK1, KIAA0137
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1) (Tousled- like kinase 1) (PKU-beta).

TLK1_MOUSE
NC score	0.824236 (rank : 326)	θ value	2.0648e-12 (rank : 493)
Query Neighborhood Hits	1959	Target Neighborhood Hits	947	Shared Neighborhood Hits	768
SwissProt Accessions	Q8C0V0	Gene names	Tlk1
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1) (Tousled- like kinase 1).

M4K1_MOUSE
NC score	0.823934 (rank : 327)	θ value	6.41864e-14 (rank : 434)
Query Neighborhood Hits	1959	Target Neighborhood Hits	858	Shared Neighborhood Hits	827
SwissProt Accessions	P70218, Q8R3R0, Q99K62	Gene names	Map4k1, Hpk1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1) (Hematopoietic progenitor kinase) (HPK).

ARBK2_HUMAN
NC score	0.823913 (rank : 328)	θ value	1.29331e-14 (rank : 388)
Query Neighborhood Hits	1959	Target Neighborhood Hits	849	Shared Neighborhood Hits	810
SwissProt Accessions	P35626, Q9UGW9	Gene names	ADRBK2, BARK2, GRK3
Domain Architecture
Description	Beta-adrenergic receptor kinase 2 (EC 2.7.11.15) (Beta-ARK-2) (G- protein-coupled receptor kinase 3).

STK38_HUMAN
NC score	0.823618 (rank : 329)	θ value	6.20254e-17 (rank : 276)
Query Neighborhood Hits	1959	Target Neighborhood Hits	840	Shared Neighborhood Hits	796
SwissProt Accessions	Q15208	Gene names	STK38, NDR1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1 protein kinase) (Nuclear Dbf2-related kinase 1).

ARBK1_MOUSE
NC score	0.823607 (rank : 330)	θ value	9.90251e-15 (rank : 379)
Query Neighborhood Hits	1959	Target Neighborhood Hits	849	Shared Neighborhood Hits	812
SwissProt Accessions	Q99MK8, Q99LL8	Gene names	Adrbk1, Grk2
Domain Architecture
Description	Beta-adrenergic receptor kinase 1 (EC 2.7.11.15) (Beta-ARK-1) (G- protein-coupled receptor kinase 2).

STK38_MOUSE
NC score	0.823557 (rank : 331)	θ value	2.13179e-17 (rank : 253)
Query Neighborhood Hits	1959	Target Neighborhood Hits	838	Shared Neighborhood Hits	796
SwissProt Accessions	Q91VJ4	Gene names	Stk38, Ndr1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1 protein kinase) (Nuclear Dbf2-related kinase 1).

M4K2_MOUSE
NC score	0.823548 (rank : 332)	θ value	2.20605e-14 (rank : 410)
Query Neighborhood Hits	1959	Target Neighborhood Hits	843	Shared Neighborhood Hits	813
SwissProt Accessions	Q61161	Gene names	Map4k2, Rab8ip
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Germinal center kinase) (GCK) (Rab8-interacting protein).

M4K2_HUMAN
NC score	0.823502 (rank : 333)	θ value	2.20605e-14 (rank : 409)
Query Neighborhood Hits	1959	Target Neighborhood Hits	850	Shared Neighborhood Hits	820
SwissProt Accessions	Q12851	Gene names	MAP4K2, GCK, RAB8IP
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Germinal center kinase) (GC kinase) (Rab8-interacting protein) (B lymphocyte serine/threonine-protein kinase).

TLK2_HUMAN
NC score	0.823047 (rank : 334)	θ value	1.58096e-12 (rank : 484)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1044	Shared Neighborhood Hits	792
SwissProt Accessions	Q86UE8, Q9UKI7, Q9Y4F7	Gene names	TLK2
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (Tousled- like kinase 2) (PKU-alpha).

CSKP_HUMAN
NC score	0.822967 (rank : 335)	θ value	1.37539e-32 (rank : 31)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1022	Shared Neighborhood Hits	816
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

CDK3_HUMAN
NC score	0.822810 (rank : 336)	θ value	8.95645e-16 (rank : 329)
Query Neighborhood Hits	1959	Target Neighborhood Hits	843	Shared Neighborhood Hits	820
SwissProt Accessions	Q00526	Gene names	CDK3
Domain Architecture
Description	Cell division protein kinase 3 (EC 2.7.11.22).

PMYT1_HUMAN
NC score	0.822328 (rank : 337)	θ value	8.38298e-14 (rank : 441)
Query Neighborhood Hits	1959	Target Neighborhood Hits	814	Shared Neighborhood Hits	795
SwissProt Accessions	Q99640, O14731, Q7LE24, Q8TCM9	Gene names	PKMYT1, MYT1
Domain Architecture	No domain graphic available
Description	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase).

ICK_MOUSE
NC score	0.821875 (rank : 338)	θ value	1.68911e-14 (rank : 399)
Query Neighborhood Hits	1959	Target Neighborhood Hits	860	Shared Neighborhood Hits	831
SwissProt Accessions	Q9JKV2, Q8K138	Gene names	Ick
Domain Architecture
Description	Serine/threonine-protein kinase ICK (EC 2.7.11.22) (Intestinal cell kinase) (mICK) (MAK-related kinase) (MRK).

MASTL_HUMAN
NC score	0.821750 (rank : 339)	θ value	8.97725e-08 (rank : 675)
Query Neighborhood Hits	1959	Target Neighborhood Hits	894	Shared Neighborhood Hits	828
SwissProt Accessions	Q96GX5, Q5T8D5, Q5T8D7, Q8NCD6, Q96SJ5	Gene names	MASTL, THC2
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase-like (EC 2.7.11.1).

MASTL_MOUSE
NC score	0.821362 (rank : 340)	θ value	6.87365e-08 (rank : 668)
Query Neighborhood Hits	1959	Target Neighborhood Hits	862	Shared Neighborhood Hits	823
SwissProt Accessions	Q8C0P0, Q5RJW0, Q6NXX9, Q8BVF3, Q9CZH9, Q9D9V0	Gene names	Mastl
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase-like (EC 2.7.11.1).

MAK_MOUSE
NC score	0.821334 (rank : 341)	θ value	8.10077e-17 (rank : 278)
Query Neighborhood Hits	1959	Target Neighborhood Hits	873	Shared Neighborhood Hits	830
SwissProt Accessions	Q04859	Gene names	Mak, Rck
Domain Architecture
Description	Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male germ cell- associated kinase) (Protein kinase RCK).

CDK2_HUMAN
NC score	0.821290 (rank : 342)	θ value	1.24977e-17 (rank : 243)
Query Neighborhood Hits	1959	Target Neighborhood Hits	832	Shared Neighborhood Hits	814
SwissProt Accessions	P24941	Gene names	CDK2
Domain Architecture
Description	Cell division protein kinase 2 (EC 2.7.11.22) (p33 protein kinase).

ICK_HUMAN
NC score	0.821249 (rank : 343)	θ value	1.29331e-14 (rank : 390)
Query Neighborhood Hits	1959	Target Neighborhood Hits	867	Shared Neighborhood Hits	829
SwissProt Accessions	Q9UPZ9, O75985, Q5THL2, Q8IYH8, Q9BX17, Q9NYX3	Gene names	ICK, KIAA0936
Domain Architecture
Description	Serine/threonine-protein kinase ICK (EC 2.7.11.22) (Intestinal cell kinase) (hICK) (MAK-related kinase) (MRK) (Laryngeal cancer kinase 2) (LCK2).

TLK2_MOUSE
NC score	0.820870 (rank : 344)	θ value	1.58096e-12 (rank : 485)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1088	Shared Neighborhood Hits	799
SwissProt Accessions	O55047, Q9D5Y5	Gene names	Tlk2
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (Tousled- like kinase 2).

M4K5_MOUSE
NC score	0.820256 (rank : 345)	θ value	2.88119e-14 (rank : 416)
Query Neighborhood Hits	1959	Target Neighborhood Hits	839	Shared Neighborhood Hits	810
SwissProt Accessions	Q8BPM2, Q6PEQ2, Q8C3U5, Q8CGF3, Q99LM7, Q9CX73	Gene names	Map4k5
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 5) (MEK kinase kinase 5) (MEKKK 5).

MP2K5_HUMAN
NC score	0.819942 (rank : 346)	θ value	6.64225e-11 (rank : 551)
Query Neighborhood Hits	1959	Target Neighborhood Hits	837	Shared Neighborhood Hits	817
SwissProt Accessions	Q13163	Gene names	MAP2K5, MEK5, MKK5, PRKMK5
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 5 (EC 2.7.12.2) (MAP kinase kinase 5) (MAPKK 5) (MAPK/ERK kinase 5).

CDK7_MOUSE
NC score	0.819901 (rank : 347)	θ value	4.44505e-15 (rank : 363)
Query Neighborhood Hits	1959	Target Neighborhood Hits	835	Shared Neighborhood Hits	812
SwissProt Accessions	Q03147, Q99KK3	Gene names	Cdk7, Cdkn7, Crk4, Mo15, Mpk-7
Domain Architecture
Description	Cell division protein kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (CDK- activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 kDa protein kinase) (P39 Mo15) (Protein-tyrosine kinase MPK-7) (CR4 protein kinase) (CRK4).

MAK_HUMAN
NC score	0.819832 (rank : 348)	θ value	2.35696e-16 (rank : 301)
Query Neighborhood Hits	1959	Target Neighborhood Hits	857	Shared Neighborhood Hits	822
SwissProt Accessions	P20794, Q9NUH7	Gene names	MAK
Domain Architecture
Description	Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male germ cell- associated kinase).

CDK7_HUMAN
NC score	0.819809 (rank : 349)	θ value	4.44505e-15 (rank : 362)
Query Neighborhood Hits	1959	Target Neighborhood Hits	833	Shared Neighborhood Hits	811
SwissProt Accessions	P50613, Q9BS60, Q9UE19	Gene names	CDK7, MO15
Domain Architecture
Description	Cell division protein kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (CDK- activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 kDa protein kinase) (P39 Mo15) (STK1) (CAK1).

PFTK1_MOUSE
NC score	0.819559 (rank : 350)	θ value	6.85773e-16 (rank : 325)
Query Neighborhood Hits	1959	Target Neighborhood Hits	835	Shared Neighborhood Hits	808
SwissProt Accessions	O35495, O35848	Gene names	Pftk1
Domain Architecture
Description	Serine/threonine-protein kinase PFTAIRE-1 (EC 2.7.11.22).

PFTK1_HUMAN
NC score	0.819522 (rank : 351)	θ value	3.07829e-16 (rank : 307)
Query Neighborhood Hits	1959	Target Neighborhood Hits	834	Shared Neighborhood Hits	808
SwissProt Accessions	O94921, Q75N06, Q75N22, Q8N764, Q9H3D7, Q9UDR0	Gene names	PFTK1, KIAA0834
Domain Architecture
Description	Serine/threonine-protein kinase PFTAIRE-1 (EC 2.7.11.22).

M4K5_HUMAN
NC score	0.818971 (rank : 352)	θ value	2.20605e-14 (rank : 411)
Query Neighborhood Hits	1959	Target Neighborhood Hits	845	Shared Neighborhood Hits	815
SwissProt Accessions	Q9Y4K4, Q8IYF6	Gene names	MAP4K5
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 5) (MEK kinase kinase 5) (MEKKK 5) (Kinase homologous to SPS1/STE20) (KHS).

ST38L_MOUSE
NC score	0.818944 (rank : 353)	θ value	2.97466e-19 (rank : 194)
Query Neighborhood Hits	1959	Target Neighborhood Hits	821	Shared Neighborhood Hits	788
SwissProt Accessions	Q7TSE6, Q6P6K6, Q8BWK4	Gene names	Stk38l, Ndr2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 38-like (EC 2.7.11.1) (NDR2 protein kinase) (Nuclear Dbf2-related kinase 2).

CDK2_MOUSE
NC score	0.818635 (rank : 354)	θ value	8.95645e-16 (rank : 328)
Query Neighborhood Hits	1959	Target Neighborhood Hits	828	Shared Neighborhood Hits	812
SwissProt Accessions	P97377, O55105	Gene names	Cdk2
Domain Architecture
Description	Cell division protein kinase 2 (EC 2.7.11.22).

MK15_HUMAN
NC score	0.818521 (rank : 355)	θ value	1.63604e-09 (rank : 599)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1038	Shared Neighborhood Hits	922
SwissProt Accessions	Q8TD08, Q2TCF9, Q8N362	Gene names	MAPK15, ERK8
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 8).

DMPK_MOUSE
NC score	0.818419 (rank : 356)	θ value	2.60593e-15 (rank : 352)
Query Neighborhood Hits	1959	Target Neighborhood Hits	908	Shared Neighborhood Hits	811
SwissProt Accessions	P54265	Gene names	Dmpk, Dm15, Mdpk
Domain Architecture
Description	Myotonin-protein kinase (EC 2.7.11.1) (Myotonic dystrophy protein kinase) (MDPK) (DM-kinase) (DMK) (DMPK) (MT-PK).

MP2K7_HUMAN
NC score	0.818282 (rank : 357)	θ value	3.08544e-08 (rank : 655)
Query Neighborhood Hits	1959	Target Neighborhood Hits	833	Shared Neighborhood Hits	806
SwissProt Accessions	O14733, O14648, O14816, O60452, O60453	Gene names	MAP2K7, JNKK2, MKK7, PRKMK7
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 7 (EC 2.7.12.2) (MAP kinase kinase 7) (MAPKK 7) (MAPK/ERK kinase 7) (JNK-activating kinase 2) (c-Jun N-terminal kinase kinase 2) (JNK kinase 2) (JNKK 2).

DMPK_HUMAN
NC score	0.817953 (rank : 358)	θ value	3.76295e-14 (rank : 420)
Query Neighborhood Hits	1959	Target Neighborhood Hits	944	Shared Neighborhood Hits	821
SwissProt Accessions	Q09013, Q16205	Gene names	DMPK, MDPK
Domain Architecture
Description	Myotonin-protein kinase (EC 2.7.11.1) (Myotonic dystrophy protein kinase) (MDPK) (DM-kinase) (DMK) (DMPK) (MT-PK).

PCTK3_MOUSE
NC score	0.816978 (rank : 359)	θ value	1.42992e-13 (rank : 447)
Query Neighborhood Hits	1959	Target Neighborhood Hits	834	Shared Neighborhood Hits	811
SwissProt Accessions	Q04899	Gene names	Pctk3
Domain Architecture
Description	Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22) (PCTAIRE- motif protein kinase 3).

F5006_MOUSE
NC score	0.816639 (rank : 360)	θ value	7.59969e-07 (rank : 732)
Query Neighborhood Hits	1959	Target Neighborhood Hits	793	Shared Neighborhood Hits	785
SwissProt Accessions	Q5SYL1	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase FLJ25006 (EC 2.7.11.1).

CDK5_HUMAN
NC score	0.816289 (rank : 361)	θ value	2.60593e-15 (rank : 351)
Query Neighborhood Hits	1959	Target Neighborhood Hits	826	Shared Neighborhood Hits	810
SwissProt Accessions	Q00535	Gene names	CDK5
Domain Architecture
Description	Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE).

PCTK1_HUMAN
NC score	0.816159 (rank : 362)	θ value	4.16044e-13 (rank : 462)
Query Neighborhood Hits	1959	Target Neighborhood Hits	832	Shared Neighborhood Hits	810
SwissProt Accessions	Q00536	Gene names	PCTK1
Domain Architecture
Description	Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22) (PCTAIRE- motif protein kinase 1).

CDK5_MOUSE
NC score	0.816152 (rank : 363)	θ value	1.99529e-15 (rank : 341)
Query Neighborhood Hits	1959	Target Neighborhood Hits	826	Shared Neighborhood Hits	810
SwissProt Accessions	P49615	Gene names	Cdk5, Crk6
Domain Architecture
Description	Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) (CRK6).

PCTK1_MOUSE
NC score	0.815921 (rank : 364)	θ value	4.16044e-13 (rank : 463)
Query Neighborhood Hits	1959	Target Neighborhood Hits	832	Shared Neighborhood Hits	810
SwissProt Accessions	Q04735	Gene names	Pctk1, Crk5
Domain Architecture
Description	Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22) (PCTAIRE- motif protein kinase 1) (CRK5).

CD2L7_HUMAN
NC score	0.815611 (rank : 365)	θ value	9.90251e-15 (rank : 380)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1275	Shared Neighborhood Hits	996
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

CDK6_MOUSE
NC score	0.815308 (rank : 366)	θ value	6.00763e-12 (rank : 512)
Query Neighborhood Hits	1959	Target Neighborhood Hits	837	Shared Neighborhood Hits	815
SwissProt Accessions	Q64261, Q9R1D2, Q9R1D3	Gene names	Cdk6, Crk2
Domain Architecture
Description	Cell division protein kinase 6 (EC 2.7.11.22) (Serine/threonine- protein kinase PLSTIRE) (CRK2).

CCRK_HUMAN
NC score	0.815258 (rank : 367)	θ value	9.26847e-13 (rank : 472)
Query Neighborhood Hits	1959	Target Neighborhood Hits	835	Shared Neighborhood Hits	817
SwissProt Accessions	Q8IZL9, Q5EDC4, Q5VYW1, Q9BUF4	Gene names	CCRK, CDCH
Domain Architecture	No domain graphic available
Description	Cell cycle-related kinase (EC 2.7.11.22) (Cyclin-kinase-activating kinase p42) (CDK-activating kinase p42) (CAK-kinase p42) (Cyclin- dependent protein kinase H).

NRK_HUMAN
NC score	0.814918 (rank : 368)	θ value	1.86753e-13 (rank : 450)
Query Neighborhood Hits	1959	Target Neighborhood Hits	931	Shared Neighborhood Hits	834
SwissProt Accessions	Q7Z2Y5, Q32ND6, Q5H9K2, Q6ZMP2	Gene names	NRK
Domain Architecture	No domain graphic available
Description	Nik-related protein kinase (EC 2.7.11.1).

PCTK3_HUMAN
NC score	0.814908 (rank : 369)	θ value	8.38298e-14 (rank : 440)
Query Neighborhood Hits	1959	Target Neighborhood Hits	827	Shared Neighborhood Hits	804
SwissProt Accessions	Q07002, Q5VXQ2, Q96F90	Gene names	PCTK3
Domain Architecture
Description	Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22) (PCTAIRE- motif protein kinase 3).

CDK6_HUMAN
NC score	0.814738 (rank : 370)	θ value	6.00763e-12 (rank : 511)
Query Neighborhood Hits	1959	Target Neighborhood Hits	837	Shared Neighborhood Hits	815
SwissProt Accessions	Q00534	Gene names	CDK6
Domain Architecture
Description	Cell division protein kinase 6 (EC 2.7.11.22) (Serine/threonine- protein kinase PLSTIRE).

CCRK_MOUSE
NC score	0.814684 (rank : 371)	θ value	5.43371e-13 (rank : 464)
Query Neighborhood Hits	1959	Target Neighborhood Hits	832	Shared Neighborhood Hits	815
SwissProt Accessions	Q9JHU3, Q5EDC2	Gene names	Ccrk, Cdch
Domain Architecture	No domain graphic available
Description	Cell cycle-related kinase (EC 2.7.11.22) (Cyclin-kinase-activating kinase p42) (CDK-activating kinase p42) (CAK-kinase p42) (CDK-related protein kinase PNQLARE) (Cyclin-dependent protein kinase H).

MK15_MOUSE
NC score	0.814666 (rank : 372)	θ value	3.08544e-08 (rank : 654)
Query Neighborhood Hits	1959	Target Neighborhood Hits	843	Shared Neighborhood Hits	819
SwissProt Accessions	Q80Y86	Gene names	Mapk15, Erk7
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 7).

GSK3A_HUMAN
NC score	0.814498 (rank : 373)	θ value	5.43371e-13 (rank : 466)
Query Neighborhood Hits	1959	Target Neighborhood Hits	835	Shared Neighborhood Hits	794
SwissProt Accessions	P49840, O14959	Gene names	GSK3A
Domain Architecture
Description	Glycogen synthase kinase-3 alpha (EC 2.7.11.26) (GSK-3 alpha).

MK12_MOUSE
NC score	0.814397 (rank : 374)	θ value	4.91457e-14 (rank : 430)
Query Neighborhood Hits	1959	Target Neighborhood Hits	835	Shared Neighborhood Hits	814
SwissProt Accessions	O08911, Q9D0M4	Gene names	Mapk12, Sapk3
Domain Architecture
Description	Mitogen-activated protein kinase 12 (EC 2.7.11.24) (Extracellular signal-regulated kinase 6) (ERK-6) (Stress-activated protein kinase 3) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma).

NRK_MOUSE
NC score	0.813563 (rank : 375)	θ value	3.18553e-13 (rank : 459)
Query Neighborhood Hits	1959	Target Neighborhood Hits	899	Shared Neighborhood Hits	832
SwissProt Accessions	Q9R0G8, Q6NV55, Q8C9S9, Q9R0S4	Gene names	Nrk, Nesk
Domain Architecture	No domain graphic available
Description	Nik-related protein kinase (EC 2.7.11.1) (Nck-interacting kinase-like embryo specific kinase) (NIK-like embryo-specific kinase) (NESK).

PCTK2_HUMAN
NC score	0.813431 (rank : 376)	θ value	2.88119e-14 (rank : 418)
Query Neighborhood Hits	1959	Target Neighborhood Hits	837	Shared Neighborhood Hits	811
SwissProt Accessions	Q00537, Q8NEB8	Gene names	PCTK2
Domain Architecture
Description	Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22) (PCTAIRE- motif protein kinase 2).

STK16_HUMAN
NC score	0.813081 (rank : 377)	θ value	9.92553e-07 (rank : 739)
Query Neighborhood Hits	1959	Target Neighborhood Hits	824	Shared Neighborhood Hits	808
SwissProt Accessions	O75716, Q96KI2, Q9UEN3, Q9UP78	Gene names	STK16, MPSK1, PKL12, TSF1
Domain Architecture
Description	Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Protein kinase PKL12) (Myristoylated and palmitoylated serine/threonine-protein kinase) (MPSK) (TGF-beta-stimulated factor 1) (TSF-1) (hPSK).

PCTK2_MOUSE
NC score	0.813079 (rank : 378)	θ value	3.76295e-14 (rank : 424)
Query Neighborhood Hits	1959	Target Neighborhood Hits	836	Shared Neighborhood Hits	811
SwissProt Accessions	Q8K0D0	Gene names	Pctk2
Domain Architecture
Description	Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22) (PCTAIRE- motif protein kinase 2).

MK12_HUMAN
NC score	0.812883 (rank : 379)	θ value	5.43371e-13 (rank : 468)
Query Neighborhood Hits	1959	Target Neighborhood Hits	830	Shared Neighborhood Hits	812
SwissProt Accessions	P53778, Q14260, Q99588, Q99672	Gene names	MAPK12, ERK6, SAPK3
Domain Architecture
Description	Mitogen-activated protein kinase 12 (EC 2.7.11.24) (Extracellular signal-regulated kinase 6) (ERK-6) (ERK5) (Stress-activated protein kinase 3) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma).

F5006_HUMAN
NC score	0.812615 (rank : 380)	θ value	4.45536e-07 (rank : 713)
Query Neighborhood Hits	1959	Target Neighborhood Hits	794	Shared Neighborhood Hits	782
SwissProt Accessions	Q96LW2, Q49A48	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase FLJ25006 (EC 2.7.11.1).

GSK3B_MOUSE
NC score	0.812555 (rank : 381)	θ value	2.0648e-12 (rank : 488)
Query Neighborhood Hits	1959	Target Neighborhood Hits	800	Shared Neighborhood Hits	788
SwissProt Accessions	Q9WV60	Gene names	Gsk3b
Domain Architecture
Description	Glycogen synthase kinase-3 beta (EC 2.7.11.26) (GSK-3 beta).

GSK3B_HUMAN
NC score	0.812552 (rank : 382)	θ value	2.0648e-12 (rank : 487)
Query Neighborhood Hits	1959	Target Neighborhood Hits	801	Shared Neighborhood Hits	788
SwissProt Accessions	P49841, Q9BWH3, Q9UL47	Gene names	GSK3B
Domain Architecture
Description	Glycogen synthase kinase-3 beta (EC 2.7.11.26) (GSK-3 beta).

STK16_MOUSE
NC score	0.812350 (rank : 383)	θ value	3.41135e-07 (rank : 708)
Query Neighborhood Hits	1959	Target Neighborhood Hits	824	Shared Neighborhood Hits	804
SwissProt Accessions	O88697, Q9JMJ0, Q9JMJ1, Q9QX00	Gene names	Stk16, Edpk, Krct, Mpsk1, Pkl12, Tsf1
Domain Architecture
Description	Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Protein kinase PKL12) (Myristoylated and palmitoylated serine/threonine-protein kinase) (MPSK) (TGF-beta-stimulated factor 1) (TSF-1) (Protein kinase Krct).

MKNK1_HUMAN
NC score	0.812141 (rank : 384)	θ value	4.16044e-13 (rank : 461)
Query Neighborhood Hits	1959	Target Neighborhood Hits	701	Shared Neighborhood Hits	684
SwissProt Accessions	Q9BUB5, O00312, Q5TC06, Q6V0N6	Gene names	MKNK1, MNK1
Domain Architecture
Description	MAP kinase-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (Mnk1).

KPCA_MOUSE
NC score	0.812091 (rank : 385)	θ value	1.80466e-16 (rank : 298)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1067	Shared Neighborhood Hits	817
SwissProt Accessions	P20444	Gene names	Prkca, Pkca
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

KPCA_HUMAN
NC score	0.811523 (rank : 386)	θ value	3.28887e-18 (rank : 222)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1070	Shared Neighborhood Hits	821
SwissProt Accessions	P17252, Q15137, Q96RE4	Gene names	PRKCA, PKCA, PRKACA
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

MP2K4_HUMAN
NC score	0.811380 (rank : 387)	θ value	1.17247e-07 (rank : 679)
Query Neighborhood Hits	1959	Target Neighborhood Hits	832	Shared Neighborhood Hits	811
SwissProt Accessions	P45985, Q5U0B8	Gene names	MAP2K4, JNKK1, MKK4, PRKMK4, SERK1
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 4 (EC 2.7.12.2) (MAP kinase kinase 4) (JNK-activating kinase 1) (c-Jun N-terminal kinase kinase 1) (JNKK) (SAPK/ERK kinase 1) (SEK1).

MP2K4_MOUSE
NC score	0.811336 (rank : 388)	θ value	1.53129e-07 (rank : 685)
Query Neighborhood Hits	1959	Target Neighborhood Hits	833	Shared Neighborhood Hits	811
SwissProt Accessions	P47809	Gene names	Map2k4, Jnkk1, Prkmk4, Sek1, Serk1
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 4 (EC 2.7.12.2) (MAP kinase kinase 4) (MAPKK 4) (MAPK/ERK kinase 4) (JNK-activating kinase 1) (C-JUN N-terminal kinase kinase 1) (JNK kinase 1) (JNKK 1) (SAPK/ERK kinase 1) (SEK1).

MK07_MOUSE
NC score	0.811250 (rank : 389)	θ value	4.91457e-14 (rank : 429)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1054	Shared Neighborhood Hits	931
SwissProt Accessions	Q9WVS8	Gene names	Mapk7, Erk5
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase).

ERN1_HUMAN
NC score	0.811086 (rank : 390)	θ value	5.08577e-11 (rank : 544)
Query Neighborhood Hits	1959	Target Neighborhood Hits	829	Shared Neighborhood Hits	805
SwissProt Accessions	O75460	Gene names	ERN1, IRE1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase/endoribonuclease IRE1 precursor (Inositol-requiring protein 1) (hIRE1p) (IRE1a) (Ire1-alpha) (Endoplasmic reticulum-to-nucleus signaling 1) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)].

MK14_MOUSE
NC score	0.810815 (rank : 391)	θ value	5.08577e-11 (rank : 547)
Query Neighborhood Hits	1959	Target Neighborhood Hits	838	Shared Neighborhood Hits	817
SwissProt Accessions	P47811, O08666, Q3UZS3, Q8C289, Q9JLV8, Q9QZ80	Gene names	Mapk14, Crk1, Csbp1, Csbp2
Domain Architecture
Description	Mitogen-activated protein kinase 14 (EC 2.7.11.24) (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (CRK1).

STK40_HUMAN
NC score	0.810742 (rank : 392)	θ value	1.80886e-08 (rank : 640)
Query Neighborhood Hits	1959	Target Neighborhood Hits	751	Shared Neighborhood Hits	734
SwissProt Accessions	Q8N2I9, Q5VTK8, Q5VTK9, Q6ZMN1, Q8N2J8, Q8N3I6, Q96HN6, Q96I44, Q9BSA3, Q9H7H6	Gene names	STK40, SHIK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 40 (EC 2.7.11.1) (SINK-homologous serine/threonine-protein kinase).

MK07_HUMAN
NC score	0.810675 (rank : 393)	θ value	1.09485e-13 (rank : 444)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1087	Shared Neighborhood Hits	944
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

MK14_HUMAN
NC score	0.810626 (rank : 394)	θ value	3.89403e-11 (rank : 538)
Query Neighborhood Hits	1959	Target Neighborhood Hits	838	Shared Neighborhood Hits	817
SwissProt Accessions	Q16539, O60776, Q13083, Q14084, Q8TDX0	Gene names	MAPK14, CSBP, CSBP1, CSBP2, MXI2
Domain Architecture
Description	Mitogen-activated protein kinase 14 (EC 2.7.11.24) (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Cytokine suppressive anti-inflammatory drug-binding protein) (CSAID-binding protein) (CSBP) (MAX-interacting protein 2) (MAP kinase MXI2) (SAPK2A).

STK40_MOUSE
NC score	0.810611 (rank : 395)	θ value	1.80886e-08 (rank : 641)
Query Neighborhood Hits	1959	Target Neighborhood Hits	751	Shared Neighborhood Hits	734
SwissProt Accessions	Q7TNL3, Q3U3G3, Q811D6, Q8BKT1, Q9D7K3	Gene names	Stk40, Lyk4
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 40 (EC 2.7.11.1) (Serine/threonine- protein kinase lyk4).

AL2S7_HUMAN
NC score	0.810367 (rank : 396)	θ value	9.90251e-15 (rank : 378)
Query Neighborhood Hits	1959	Target Neighborhood Hits	831	Shared Neighborhood Hits	809
SwissProt Accessions	Q96Q40, Q4ZG86, Q53TV1	Gene names	ALS2CR7
Domain Architecture
Description	Serine/threonine-protein kinase ALS2CR7 (EC 2.7.11.22) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein).

ERN1_MOUSE
NC score	0.810182 (rank : 397)	θ value	8.67504e-11 (rank : 553)
Query Neighborhood Hits	1959	Target Neighborhood Hits	823	Shared Neighborhood Hits	803
SwissProt Accessions	Q9EQY0, Q9D340	Gene names	Ern1, Ire1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase/endoribonuclease IRE1 precursor (Inositol-requiring protein 1) (IRE1a) (Ire1-alpha) (Endoplasmic reticulum-to-nucleus signaling 1) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)].

MK13_MOUSE
NC score	0.810029 (rank : 398)	θ value	1.09485e-13 (rank : 445)
Query Neighborhood Hits	1959	Target Neighborhood Hits	832	Shared Neighborhood Hits	815
SwissProt Accessions	Q9Z1B7, Q99M57	Gene names	Mapk13, Serk4
Domain Architecture
Description	Mitogen-activated protein kinase 13 (EC 2.7.11.24) (Stress-activated protein kinase 4) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta).

CD2L5_MOUSE
NC score	0.810020 (rank : 399)	θ value	1.09485e-13 (rank : 443)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1011	Shared Neighborhood Hits	877
SwissProt Accessions	Q69ZA1, Q80V11, Q8BZG1, Q8K0A4	Gene names	Cdc2l5, Kiaa1791
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5).

CD2L5_HUMAN
NC score	0.809697 (rank : 400)	θ value	1.09485e-13 (rank : 442)
Query Neighborhood Hits	1959	Target Neighborhood Hits	987	Shared Neighborhood Hits	859
SwissProt Accessions	Q14004, Q6DKQ9, Q75MH4, Q75MH5, Q96JN4, Q9H4A0, Q9H4A1, Q9UDR4	Gene names	CDC2L5, CDC2L, CHED, KIAA1791
Domain Architecture
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5) (Cholinesterase-related cell division controller).

TAOK2_HUMAN
NC score	0.809454 (rank : 401)	θ value	5.8054e-15 (rank : 373)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1172	Shared Neighborhood Hits	864
SwissProt Accessions	Q9UL54, O94957, Q6UW73, Q7LC09, Q9NSW2	Gene names	TAOK2, KIAA0881, MAP3K17, PSK, PSK1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Thousand and one amino acid protein 2) (Prostate-derived STE20-like kinase 1) (PSK-1) (Kinase from chicken homolog C) (hKFC-C).

MK04_HUMAN
NC score	0.809151 (rank : 402)	θ value	4.59992e-12 (rank : 508)
Query Neighborhood Hits	1959	Target Neighborhood Hits	837	Shared Neighborhood Hits	815
SwissProt Accessions	P31152	Gene names	MAPK4, ERK4, PRKM4
Domain Architecture
Description	Mitogen-activated protein kinase 4 (EC 2.7.11.24) (Extracellular signal-regulated kinase 4) (ERK-4) (MAP kinase isoform p63) (p63- MAPK).

MP2K3_MOUSE
NC score	0.808867 (rank : 403)	θ value	1.99992e-07 (rank : 692)
Query Neighborhood Hits	1959	Target Neighborhood Hits	826	Shared Neighborhood Hits	811
SwissProt Accessions	O09110, P97293, Q91VX1	Gene names	Map2k3, Mkk3, Prkmk3
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 3 (EC 2.7.12.2) (MAP kinase kinase 3) (MAPKK 3) (MAPK/ERK kinase 3).

MK04_MOUSE
NC score	0.808831 (rank : 404)	θ value	4.91457e-14 (rank : 428)
Query Neighborhood Hits	1959	Target Neighborhood Hits	852	Shared Neighborhood Hits	818
SwissProt Accessions	Q6P5G0	Gene names	Mapk4, Erk4, Prkm4
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 4 (EC 2.7.11.24) (Extracellular signal-regulated kinase 4) (ERK-4).

NLK_MOUSE
NC score	0.808533 (rank : 405)	θ value	1.16975e-15 (rank : 336)
Query Neighborhood Hits	1959	Target Neighborhood Hits	839	Shared Neighborhood Hits	822
SwissProt Accessions	O54949, Q6PF98	Gene names	Nlk
Domain Architecture	No domain graphic available
Description	Serine/threonine kinase NLK (EC 2.7.11.24) (Nemo-like kinase).

NLK_HUMAN
NC score	0.808482 (rank : 406)	θ value	1.16975e-15 (rank : 335)
Query Neighborhood Hits	1959	Target Neighborhood Hits	840	Shared Neighborhood Hits	822
SwissProt Accessions	Q9UBE8, Q2PNI9, Q6P2A3	Gene names	NLK, LAK1
Domain Architecture	No domain graphic available
Description	Serine/threonine kinase NLK (EC 2.7.11.24) (Nemo-like kinase) (Protein LAK1).

MK13_HUMAN
NC score	0.808373 (rank : 407)	θ value	1.33837e-11 (rank : 527)
Query Neighborhood Hits	1959	Target Neighborhood Hits	829	Shared Neighborhood Hits	813
SwissProt Accessions	O15264, O14739, O15124, Q9UNU0	Gene names	MAPK13, PRKM13, SAPK4
Domain Architecture
Description	Mitogen-activated protein kinase 13 (EC 2.7.11.24) (Stress-activated protein kinase 4) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta).

ERN2_HUMAN
NC score	0.808037 (rank : 408)	θ value	1.33837e-11 (rank : 526)
Query Neighborhood Hits	1959	Target Neighborhood Hits	844	Shared Neighborhood Hits	814
SwissProt Accessions	Q76MJ5, Q6ZNC0	Gene names	ERN2, IRE2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase/endoribonuclease IRE2 precursor (Inositol-requiring protein 2) (hIRE2p) (IRE1b) (Ire1-beta) (Endoplasmic reticulum-to-nucleus signaling 2) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)].

MP2K3_HUMAN
NC score	0.807733 (rank : 409)	θ value	1.17247e-07 (rank : 678)
Query Neighborhood Hits	1959	Target Neighborhood Hits	825	Shared Neighborhood Hits	810
SwissProt Accessions	P46734, Q99441, Q9UE71, Q9UE72	Gene names	MAP2K3, MEK3, MKK3, PRKMK3
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 3 (EC 2.7.12.2) (MAP kinase kinase 3) (MAPKK 3) (MAPK/ERK kinase 3).

MOK_HUMAN
NC score	0.807527 (rank : 410)	θ value	9.26847e-13 (rank : 473)
Query Neighborhood Hits	1959	Target Neighborhood Hits	807	Shared Neighborhood Hits	793
SwissProt Accessions	Q9UQ07, Q92790, Q93067	Gene names	RAGE, MOK, RAGE1
Domain Architecture
Description	MAPK/MAK/MRK overlapping kinase (EC 2.7.11.22) (MOK protein kinase) (Renal tumor antigen 1) (RAGE-1).

SLK_MOUSE
NC score	0.807089 (rank : 411)	θ value	1.38178e-16 (rank : 292)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1798	Shared Neighborhood Hits	923
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

MINK1_MOUSE
NC score	0.806494 (rank : 412)	θ value	2.60593e-15 (rank : 354)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1451	Shared Neighborhood Hits	916
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

MINK1_HUMAN
NC score	0.806464 (rank : 413)	θ value	7.58209e-15 (rank : 376)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1477	Shared Neighborhood Hits	933
SwissProt Accessions	Q8N4C8, Q9P1X1, Q9P2R8	Gene names	MINK1, MAP4K6, MINK
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

E2AK1_MOUSE
NC score	0.806358 (rank : 414)	θ value	2.21117e-06 (rank : 756)
Query Neighborhood Hits	1959	Target Neighborhood Hits	821	Shared Neighborhood Hits	801
SwissProt Accessions	Q9Z2R9, Q8C024, Q8K123, Q9CTP5, Q9D601	Gene names	Eif2ak1, Hri
Domain Architecture
Description	Eukaryotic translation initiation factor 2-alpha kinase 1 (EC 2.7.11.1) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Heme-controlled repressor) (HCR) (Hemin-sensitive initiation factor 2-alpha kinase).

KPCG_MOUSE
NC score	0.806259 (rank : 415)	θ value	2.13179e-17 (rank : 251)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1123	Shared Neighborhood Hits	823
SwissProt Accessions	P63318, P05697	Gene names	Prkcg, Pkcc, Pkcg, Prkcc
Domain Architecture	No domain graphic available
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

TNIK_HUMAN
NC score	0.806066 (rank : 416)	θ value	2.35696e-16 (rank : 303)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1570	Shared Neighborhood Hits	940
SwissProt Accessions	Q9UKE5, O60298, Q8WUY7, Q9UKD8, Q9UKD9, Q9UKE0, Q9UKE1, Q9UKE2, Q9UKE3, Q9UKE4	Gene names	TNIK, KIAA0551
Domain Architecture
Description	TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1).

MP2K6_MOUSE
NC score	0.806036 (rank : 417)	θ value	1.38499e-08 (rank : 631)
Query Neighborhood Hits	1959	Target Neighborhood Hits	830	Shared Neighborhood Hits	811
SwissProt Accessions	P70236	Gene names	Map2k6, Prkmk6, Sapkk3
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 6 (EC 2.7.12.2) (MAP kinase kinase 6) (MAPKK 6) (MAPK/ERK kinase 6) (SAPKK3).

KPCG_HUMAN
NC score	0.806022 (rank : 418)	θ value	1.63225e-17 (rank : 250)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1126	Shared Neighborhood Hits	823
SwissProt Accessions	P05129	Gene names	PRKCG, PKCG
Domain Architecture
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

KPCB_MOUSE
NC score	0.805842 (rank : 419)	θ value	1.63225e-17 (rank : 249)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1117	Shared Neighborhood Hits	820
SwissProt Accessions	P68404, P04410, P04411	Gene names	Prkcb1, Pkcb, Prkcb
Domain Architecture	No domain graphic available
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

MK11_MOUSE
NC score	0.805756 (rank : 420)	θ value	8.67504e-11 (rank : 554)
Query Neighborhood Hits	1959	Target Neighborhood Hits	835	Shared Neighborhood Hits	816
SwissProt Accessions	Q9WUI1	Gene names	Mapk11, Prkm11
Domain Architecture
Description	Mitogen-activated protein kinase 11 (EC 2.7.11.24) (Mitogen-activated protein kinase p38 beta) (MAP kinase p38 beta) (p38B).

MK03_MOUSE
NC score	0.805754 (rank : 421)	θ value	1.38178e-16 (rank : 290)
Query Neighborhood Hits	1959	Target Neighborhood Hits	840	Shared Neighborhood Hits	817
SwissProt Accessions	Q63844, Q61531, Q8K0X5, Q91YW5	Gene names	Mapk3, Erk1, Prkm3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 3 (EC 2.7.11.24) (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase 1) (MAPK 1) (p44-ERK1) (ERT2) (p44-MAPK) (Microtubule- associated protein 2 kinase) (MNK1).

MK03_HUMAN
NC score	0.805641 (rank : 422)	θ value	5.25075e-16 (rank : 317)
Query Neighborhood Hits	1959	Target Neighborhood Hits	837	Shared Neighborhood Hits	817
SwissProt Accessions	P27361	Gene names	MAPK3, ERK1, PRKM3
Domain Architecture
Description	Mitogen-activated protein kinase 3 (EC 2.7.11.24) (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase 1) (MAPK 1) (p44-ERK1) (ERT2) (p44-MAPK) (Microtubule- associated protein 2 kinase).

CDK4_MOUSE
NC score	0.805590 (rank : 423)	θ value	2.52405e-10 (rank : 567)
Query Neighborhood Hits	1959	Target Neighborhood Hits	838	Shared Neighborhood Hits	815
SwissProt Accessions	P30285	Gene names	Cdk4, Crk3
Domain Architecture
Description	Cell division protein kinase 4 (EC 2.7.11.22) (Cyclin-dependent kinase 4) (PSK-J3) (CRK3).

KPCB_HUMAN
NC score	0.805395 (rank : 424)	θ value	1.63225e-17 (rank : 248)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1121	Shared Neighborhood Hits	821
SwissProt Accessions	P05771, O43744, P05127, Q15138, Q93060, Q9UE49, Q9UE50, Q9UEH8, Q9UJ30, Q9UJ33	Gene names	PRKCB1, PKCB, PRKCB
Domain Architecture
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

MOK_MOUSE
NC score	0.805341 (rank : 425)	θ value	2.0648e-12 (rank : 491)
Query Neighborhood Hits	1959	Target Neighborhood Hits	796	Shared Neighborhood Hits	785
SwissProt Accessions	Q9WVS4, Q8CFU4	Gene names	Rage, Mok
Domain Architecture
Description	MAPK/MAK/MRK overlapping kinase (EC 2.7.11.22) (MOK protein kinase).

SLK_HUMAN
NC score	0.805256 (rank : 426)	θ value	8.95645e-16 (rank : 333)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1775	Shared Neighborhood Hits	920
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

CDK4_HUMAN
NC score	0.805238 (rank : 427)	θ value	1.47974e-10 (rank : 562)
Query Neighborhood Hits	1959	Target Neighborhood Hits	834	Shared Neighborhood Hits	815
SwissProt Accessions	P11802, O00576	Gene names	CDK4
Domain Architecture
Description	Cell division protein kinase 4 (EC 2.7.11.22) (Cyclin-dependent kinase 4) (PSK-J3).

ERN2_MOUSE
NC score	0.805227 (rank : 428)	θ value	6.00763e-12 (rank : 514)
Query Neighborhood Hits	1959	Target Neighborhood Hits	825	Shared Neighborhood Hits	803
SwissProt Accessions	Q9Z2E3	Gene names	Ern2, Ire2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase/endoribonuclease IRE2 precursor (Inositol-requiring protein 2) (IRE1b) (Ire1-beta) (Endoplasmic reticulum-to-nucleus signaling 2) (mIre1) [Includes: Serine/threonine- protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)].

MP2K6_HUMAN
NC score	0.805215 (rank : 429)	θ value	2.79066e-09 (rank : 603)
Query Neighborhood Hits	1959	Target Neighborhood Hits	830	Shared Neighborhood Hits	810
SwissProt Accessions	P52564	Gene names	MAP2K6, MEK6, MKK6, PRKMK6
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 6 (EC 2.7.12.2) (MAP kinase kinase 6) (MAPKK 6) (MAPK/ERK kinase 6) (SAPKK3).

LATS1_HUMAN
NC score	0.805040 (rank : 430)	θ value	1.58096e-12 (rank : 480)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1057	Shared Neighborhood Hits	888
SwissProt Accessions	O95835, Q6PKD0	Gene names	LATS1, WARTS
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts).

CSK21_MOUSE
NC score	0.805000 (rank : 431)	θ value	1.17247e-07 (rank : 676)
Query Neighborhood Hits	1959	Target Neighborhood Hits	770	Shared Neighborhood Hits	763
SwissProt Accessions	Q60737	Gene names	Csnk2a1, Ckiia
Domain Architecture
Description	Casein kinase II subunit alpha (EC 2.7.11.1) (CK II).

CSK21_HUMAN
NC score	0.804781 (rank : 432)	θ value	3.08544e-08 (rank : 651)
Query Neighborhood Hits	1959	Target Neighborhood Hits	772	Shared Neighborhood Hits	763
SwissProt Accessions	P68400, P19138, P20426, Q14013	Gene names	CSNK2A1, CK2A1
Domain Architecture	No domain graphic available
Description	Casein kinase II subunit alpha (EC 2.7.11.1) (CK II).

MK09_HUMAN
NC score	0.804539 (rank : 433)	θ value	4.76016e-09 (rank : 609)
Query Neighborhood Hits	1959	Target Neighborhood Hits	842	Shared Neighborhood Hits	822
SwissProt Accessions	P45984, Q15708, Q15710, Q15711, Q8N5C5	Gene names	MAPK9, JNK2, PRKM9
Domain Architecture
Description	Mitogen-activated protein kinase 9 (EC 2.7.11.24) (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2) (JNK-55).

E2AK3_HUMAN
NC score	0.804164 (rank : 434)	θ value	2.61198e-07 (rank : 696)
Query Neighborhood Hits	1959	Target Neighborhood Hits	859	Shared Neighborhood Hits	820
SwissProt Accessions	Q9NZJ5, O95846	Gene names	EIF2AK3, PEK, PERK
Domain Architecture
Description	Eukaryotic translation initiation factor 2-alpha kinase 3 precursor (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase) (HsPEK).

MK01_HUMAN
NC score	0.803754 (rank : 435)	θ value	7.32683e-18 (rank : 233)
Query Neighborhood Hits	1959	Target Neighborhood Hits	836	Shared Neighborhood Hits	816
SwissProt Accessions	P28482	Gene names	MAPK1, ERK2, PRKM1
Domain Architecture
Description	Mitogen-activated protein kinase 1 (EC 2.7.11.24) (Extracellular signal-regulated kinase 2) (ERK-2) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2) (p42-MAPK) (ERT1).

MK01_MOUSE
NC score	0.803524 (rank : 436)	θ value	9.56915e-18 (rank : 237)
Query Neighborhood Hits	1959	Target Neighborhood Hits	836	Shared Neighborhood Hits	816
SwissProt Accessions	P63085, P27703, Q3V1U6	Gene names	Mapk1, Erk2, Mapk, Prkm1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 1 (EC 2.7.11.24) (Extracellular signal-regulated kinase 2) (ERK-2) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2) (p42-MAPK) (ERT1).

CDK10_HUMAN
NC score	0.803340 (rank : 437)	θ value	7.34386e-10 (rank : 581)
Query Neighborhood Hits	1959	Target Neighborhood Hits	831	Shared Neighborhood Hits	816
SwissProt Accessions	Q15131, Q15130	Gene names	CDK10
Domain Architecture
Description	Cell division protein kinase 10 (EC 2.7.11.22) (Serine/threonine- protein kinase PISSLRE).

CDK9_HUMAN
NC score	0.802645 (rank : 438)	θ value	5.43371e-13 (rank : 465)
Query Neighborhood Hits	1959	Target Neighborhood Hits	822	Shared Neighborhood Hits	805
SwissProt Accessions	P50750, Q5JU24, Q5JU25, Q5U006, Q96TF1	Gene names	CDK9, CDC2L4
Domain Architecture
Description	Cell division protein kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (Cyclin- dependent kinase 9) (Serine/threonine-protein kinase PITALRE) (C-2K) (Cell division cycle 2-like protein kinase 4).

E2AK3_MOUSE
NC score	0.802538 (rank : 439)	θ value	1.38499e-08 (rank : 627)
Query Neighborhood Hits	1959	Target Neighborhood Hits	851	Shared Neighborhood Hits	821
SwissProt Accessions	Q9Z2B5, Q9CTK8, Q9CWT5	Gene names	Eif2ak3, Pek, Perk
Domain Architecture
Description	Eukaryotic translation initiation factor 2-alpha kinase 3 precursor (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase).

CDK9_MOUSE
NC score	0.802008 (rank : 440)	θ value	1.2105e-12 (rank : 475)
Query Neighborhood Hits	1959	Target Neighborhood Hits	822	Shared Neighborhood Hits	805
SwissProt Accessions	Q99J95, Q3U002, Q3UMY2, Q3UPT3, Q3UQI6, Q8BTN0	Gene names	Cdk9
Domain Architecture	No domain graphic available
Description	Cell division protein kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (Cyclin- dependent kinase 9).

LATS1_MOUSE
NC score	0.801781 (rank : 441)	θ value	3.29651e-10 (rank : 572)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1027	Shared Neighborhood Hits	872
SwissProt Accessions	Q8BYR2, Q9Z0W4	Gene names	Lats1, Warts
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase).

E2AK1_HUMAN
NC score	0.801546 (rank : 442)	θ value	8.40245e-06 (rank : 779)
Query Neighborhood Hits	1959	Target Neighborhood Hits	833	Shared Neighborhood Hits	804
SwissProt Accessions	Q9BQI3, Q8NBW3, Q9HC02, Q9NYE0, Q9P0V6, Q9P1J5, Q9P2H8, Q9UHG4	Gene names	EIF2AK1, HRI, KIAA1369
Domain Architecture
Description	Eukaryotic translation initiation factor 2-alpha kinase 1 (EC 2.7.11.1) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Heme-controlled repressor) (HCR) (Hemin-sensitive initiation factor 2-alpha kinase).

WNK3_HUMAN
NC score	0.801369 (rank : 443)	θ value	2.0648e-12 (rank : 496)
Query Neighborhood Hits	1959	Target Neighborhood Hits	948	Shared Neighborhood Hits	782
SwissProt Accessions	Q9BYP7, Q9HCK6	Gene names	WNK3, KIAA1566, PRKWNK3
Domain Architecture
Description	Serine/threonine-protein kinase WNK3 (EC 2.7.11.1) (Protein kinase with no lysine 3) (Protein kinase, lysine-deficient 3).

MK09_MOUSE
NC score	0.800533 (rank : 444)	θ value	1.38499e-08 (rank : 630)
Query Neighborhood Hits	1959	Target Neighborhood Hits	843	Shared Neighborhood Hits	821
SwissProt Accessions	Q9WTU6, Q8C097, Q8VDD2, Q9WTU4, Q9WTU5	Gene names	Mapk9, Jnk2, Prkm9
Domain Architecture
Description	Mitogen-activated protein kinase 9 (EC 2.7.11.24) (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2).

LATS2_MOUSE
NC score	0.800199 (rank : 445)	θ value	1.47974e-10 (rank : 563)
Query Neighborhood Hits	1959	Target Neighborhood Hits	879	Shared Neighborhood Hits	826
SwissProt Accessions	Q7TSJ6, Q8CDJ4, Q9JMI3	Gene names	Lats2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein).

MK11_HUMAN
NC score	0.799350 (rank : 446)	θ value	9.59137e-10 (rank : 591)
Query Neighborhood Hits	1959	Target Neighborhood Hits	823	Shared Neighborhood Hits	810
SwissProt Accessions	Q15759, O00284, O15472, Q2XNF2	Gene names	MAPK11, PRKM11, SAPK2
Domain Architecture
Description	Mitogen-activated protein kinase 11 (EC 2.7.11.24) (Mitogen-activated protein kinase p38 beta) (MAP kinase p38 beta) (p38b) (p38-2) (Stress- activated protein kinase 2).

CSK22_HUMAN
NC score	0.799197 (rank : 447)	θ value	1.99992e-07 (rank : 688)
Query Neighborhood Hits	1959	Target Neighborhood Hits	758	Shared Neighborhood Hits	754
SwissProt Accessions	P19784	Gene names	CSNK2A2, CK2A2
Domain Architecture
Description	Casein kinase II subunit alpha' (EC 2.7.11.1) (CK II).

CSK22_MOUSE
NC score	0.799186 (rank : 448)	θ value	1.99992e-07 (rank : 689)
Query Neighborhood Hits	1959	Target Neighborhood Hits	758	Shared Neighborhood Hits	754
SwissProt Accessions	O54833	Gene names	Csnk2a2
Domain Architecture
Description	Casein kinase II subunit alpha' (EC 2.7.11.1) (CK II).

MK06_HUMAN
NC score	0.799038 (rank : 449)	θ value	8.38298e-14 (rank : 437)
Query Neighborhood Hits	1959	Target Neighborhood Hits	815	Shared Neighborhood Hits	790
SwissProt Accessions	Q16659, Q68DH4, Q8IYN8	Gene names	MAPK6, ERK3, PRKM6
Domain Architecture
Description	Mitogen-activated protein kinase 6 (EC 2.7.11.24) (Extracellular signal-regulated kinase 3) (ERK-3) (MAP kinase isoform p97) (p97- MAPK).

LATS2_HUMAN
NC score	0.798982 (rank : 450)	θ value	1.06045e-08 (rank : 624)
Query Neighborhood Hits	1959	Target Neighborhood Hits	884	Shared Neighborhood Hits	832
SwissProt Accessions	Q9NRM7, Q9P2X1	Gene names	LATS2, KPM
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein) (Warts-like kinase).

MK06_MOUSE
NC score	0.798884 (rank : 451)	θ value	8.38298e-14 (rank : 438)
Query Neighborhood Hits	1959	Target Neighborhood Hits	818	Shared Neighborhood Hits	791
SwissProt Accessions	Q61532, Q497T9, Q6YKB0, Q7TT30, Q80XH5, Q922U4, Q9JLU6	Gene names	Mapk6, Erk3, Prkm4, Prkm6
Domain Architecture
Description	Mitogen-activated protein kinase 6 (EC 2.7.11.24) (Extracellular signal-regulated kinase 3) (ERK-3).

MK08_MOUSE
NC score	0.798673 (rank : 452)	θ value	1.53129e-07 (rank : 684)
Query Neighborhood Hits	1959	Target Neighborhood Hits	834	Shared Neighborhood Hits	814
SwissProt Accessions	Q91Y86	Gene names	Mapk8, Jnk1, Prkm8
Domain Architecture
Description	Mitogen-activated protein kinase 8 (EC 2.7.11.24) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1).

MK08_HUMAN
NC score	0.798025 (rank : 453)	θ value	1.53129e-07 (rank : 683)
Query Neighborhood Hits	1959	Target Neighborhood Hits	834	Shared Neighborhood Hits	814
SwissProt Accessions	P45983, Q15709, Q15712, Q15713	Gene names	MAPK8, JNK1, PRKM8
Domain Architecture
Description	Mitogen-activated protein kinase 8 (EC 2.7.11.24) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1) (JNK-46).

HIPK4_HUMAN
NC score	0.797814 (rank : 454)	θ value	1.02475e-11 (rank : 520)
Query Neighborhood Hits	1959	Target Neighborhood Hits	799	Shared Neighborhood Hits	786
SwissProt Accessions	Q8NE63	Gene names	HIPK4
Domain Architecture	No domain graphic available
Description	Homeodomain-interacting protein kinase 4 (EC 2.7.11.1).

MK10_HUMAN
NC score	0.797737 (rank : 455)	θ value	1.06045e-08 (rank : 625)
Query Neighborhood Hits	1959	Target Neighborhood Hits	836	Shared Neighborhood Hits	815
SwissProt Accessions	P53779, Q15707	Gene names	MAPK10, JNK3, JNK3A, PRKM10
Domain Architecture
Description	Mitogen-activated protein kinase 10 (EC 2.7.11.24) (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3) (MAP kinase p49 3F12).

MK10_MOUSE
NC score	0.797341 (rank : 456)	θ value	4.76016e-09 (rank : 610)
Query Neighborhood Hits	1959	Target Neighborhood Hits	849	Shared Neighborhood Hits	819
SwissProt Accessions	Q61831, Q9R0U6	Gene names	Mapk10, Jnk3, Prkm10, Serk2
Domain Architecture
Description	Mitogen-activated protein kinase 10 (EC 2.7.11.24) (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3) (MAP kinase p49 3F12).

TAOK2_MOUSE
NC score	0.797158 (rank : 457)	θ value	1.99529e-15 (rank : 349)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1373	Shared Neighborhood Hits	876
SwissProt Accessions	Q6ZQ29, Q7TSS8	Gene names	Taok2, Kiaa0881
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Thousand and one amino acid protein 2).

WNK4_MOUSE
NC score	0.796823 (rank : 458)	θ value	1.133e-10 (rank : 561)
Query Neighborhood Hits	1959	Target Neighborhood Hits	961	Shared Neighborhood Hits	822
SwissProt Accessions	Q80UE6, Q4VAC1, Q80XB5, Q80XN2, Q8R0N0, Q8R340	Gene names	Wnk4, Prkwnk4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

WNK4_HUMAN
NC score	0.796143 (rank : 459)	θ value	8.67504e-11 (rank : 557)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1043	Shared Neighborhood Hits	866
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

DAPK1_HUMAN
NC score	0.795941 (rank : 460)	θ value	7.25919e-50 (rank : 10)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1130	Shared Neighborhood Hits	836
SwissProt Accessions	P53355, Q9BTL8	Gene names	DAPK1, DAPK
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

WNK1_HUMAN
NC score	0.795874 (rank : 461)	θ value	2.0648e-12 (rank : 494)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1158	Shared Neighborhood Hits	885
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

M3K13_HUMAN
NC score	0.795666 (rank : 462)	θ value	1.058e-16 (rank : 282)
Query Neighborhood Hits	1959	Target Neighborhood Hits	911	Shared Neighborhood Hits	834
SwissProt Accessions	O43283	Gene names	MAP3K13, LZK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Mixed lineage kinase) (MLK) (Leucine zipper-bearing kinase).

WNK1_MOUSE
NC score	0.794266 (rank : 463)	θ value	2.0648e-12 (rank : 495)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1179	Shared Neighborhood Hits	890
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

WNK2_HUMAN
NC score	0.794083 (rank : 464)	θ value	1.02475e-11 (rank : 525)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1407	Shared Neighborhood Hits	1022
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

M4K4_HUMAN
NC score	0.793964 (rank : 465)	θ value	7.58209e-15 (rank : 375)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1589	Shared Neighborhood Hits	905
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

CI096_HUMAN
NC score	0.793801 (rank : 466)	θ value	0.000270298 (rank : 871)
Query Neighborhood Hits	1959	Target Neighborhood Hits	821	Shared Neighborhood Hits	793
SwissProt Accessions	Q8NE28, Q5T8U8	Gene names	C9orf96
Domain Architecture	No domain graphic available
Description	Protein kinase-like protein C9orf96.

DYRK3_HUMAN
NC score	0.792781 (rank : 467)	θ value	1.74796e-11 (rank : 530)
Query Neighborhood Hits	1959	Target Neighborhood Hits	798	Shared Neighborhood Hits	784
SwissProt Accessions	O43781	Gene names	DYRK3
Domain Architecture
Description	Dual specificity tyrosine-phosphorylation-regulated kinase 3 (EC 2.7.12.1).

DAPK1_MOUSE
NC score	0.791733 (rank : 468)	θ value	1.23823e-49 (rank : 11)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1138	Shared Neighborhood Hits	836
SwissProt Accessions	Q80YE7, Q80YE6, Q8R341, Q8VDN6, Q9CSD4, Q9JJP7	Gene names	Dapk1
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

DYRK2_HUMAN
NC score	0.791454 (rank : 469)	θ value	1.25267e-09 (rank : 594)
Query Neighborhood Hits	1959	Target Neighborhood Hits	799	Shared Neighborhood Hits	779
SwissProt Accessions	Q92630	Gene names	DYRK2
Domain Architecture
Description	Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1).

RIPK5_HUMAN
NC score	0.790952 (rank : 470)	θ value	5.08577e-11 (rank : 548)
Query Neighborhood Hits	1959	Target Neighborhood Hits	864	Shared Neighborhood Hits	818
SwissProt Accessions	Q6XUX3, O75060, Q5RKT0, Q6IN87, Q6P997, Q86Y03, Q9P1S5	Gene names	RIPK5, KIAA0472, RIP5
Domain Architecture	No domain graphic available
Description	Receptor-interacting serine/threonine-protein kinase 5 (EC 2.7.11.1) (Dusty protein kinase) (Dusty PK) (RIP-homologous kinase).

RIPK5_MOUSE
NC score	0.790252 (rank : 471)	θ value	5.08577e-11 (rank : 549)
Query Neighborhood Hits	1959	Target Neighborhood Hits	874	Shared Neighborhood Hits	818
SwissProt Accessions	Q6XUX1, Q3ULK4, Q5EBN5, Q8C7D4, Q8C923, Q9CTP7	Gene names	Ripk5
Domain Architecture	No domain graphic available
Description	Receptor-interacting serine/threonine-protein kinase 5 (EC 2.7.11.1) (Dusty protein kinase) (Dusty PK).

STK10_HUMAN
NC score	0.790156 (rank : 472)	θ value	4.44505e-15 (rank : 369)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1921	Shared Neighborhood Hits	974
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

CD2L6_MOUSE
NC score	0.789542 (rank : 473)	θ value	3.41135e-07 (rank : 703)
Query Neighborhood Hits	1959	Target Neighborhood Hits	851	Shared Neighborhood Hits	814
SwissProt Accessions	Q8BWD8, Q80TM1	Gene names	Cdc2l6, Kiaa1028
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 6 (EC 2.7.11.22) (CDC2- related protein kinase 6).

CD2L6_HUMAN
NC score	0.789379 (rank : 474)	θ value	3.41135e-07 (rank : 702)
Query Neighborhood Hits	1959	Target Neighborhood Hits	844	Shared Neighborhood Hits	810
SwissProt Accessions	Q9BWU1, Q5JQZ7, Q5JR00, Q8TC78, Q9UPX2	Gene names	CDC2L6, CDK11, KIAA1028
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 6 (EC 2.7.11.22) (CDC2- related protein kinase 6) (Death-preventing kinase) (Cyclin-dependent kinase 11).

CD2L2_HUMAN
NC score	0.789288 (rank : 475)	θ value	7.34386e-10 (rank : 580)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1439	Shared Neighborhood Hits	897
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

M4K4_MOUSE
NC score	0.789108 (rank : 476)	θ value	5.43371e-13 (rank : 467)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1560	Shared Neighborhood Hits	908
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

E2AK4_HUMAN
NC score	0.789065 (rank : 477)	θ value	0.000158464 (rank : 854)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1012	Shared Neighborhood Hits	834
SwissProt Accessions	Q9P2K8, Q69YL7, Q6DC97, Q96GN6, Q9H5K1, Q9NSQ3, Q9NSZ5, Q9UJ56	Gene names	EIF2AK4, GCN2, KIAA1338
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 2-alpha kinase 4 (EC 2.7.11.1) (GCN2-like protein).

M3K12_HUMAN
NC score	0.788277 (rank : 478)	θ value	3.63628e-17 (rank : 261)
Query Neighborhood Hits	1959	Target Neighborhood Hits	940	Shared Neighborhood Hits	851
SwissProt Accessions	Q12852, Q86VQ5, Q8WY25	Gene names	MAP3K12, ZPK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

M3K12_MOUSE
NC score	0.788123 (rank : 479)	θ value	3.63628e-17 (rank : 262)
Query Neighborhood Hits	1959	Target Neighborhood Hits	957	Shared Neighborhood Hits	854
SwissProt Accessions	Q60700, P70286, Q3TLL7, Q8C4N7, Q8CBX3, Q8CDL6	Gene names	Map3k12, Zpk
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

GAK_HUMAN
NC score	0.788035 (rank : 480)	θ value	6.21693e-09 (rank : 613)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1028	Shared Neighborhood Hits	883
SwissProt Accessions	O14976, Q9BVY6	Gene names	GAK
Domain Architecture
Description	Cyclin G-associated kinase (EC 2.7.11.1).

WEE1_MOUSE
NC score	0.787748 (rank : 481)	θ value	1.38499e-08 (rank : 634)
Query Neighborhood Hits	1959	Target Neighborhood Hits	794	Shared Neighborhood Hits	762
SwissProt Accessions	P47810, Q9EPL7	Gene names	Wee1
Domain Architecture
Description	Wee1-like protein kinase (EC 2.7.10.2) (Wee1A kinase).

TAOK3_MOUSE
NC score	0.787473 (rank : 482)	θ value	2.20605e-14 (rank : 414)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1458	Shared Neighborhood Hits	874
SwissProt Accessions	Q8BYC6, Q3V3B3	Gene names	Taok3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3).

CD2L1_MOUSE
NC score	0.787465 (rank : 483)	θ value	1.9326e-10 (rank : 565)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1463	Shared Neighborhood Hits	892
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

CD2L1_HUMAN
NC score	0.787077 (rank : 484)	θ value	1.133e-10 (rank : 558)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1467	Shared Neighborhood Hits	895
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

CDK8_HUMAN
NC score	0.786461 (rank : 485)	θ value	5.81887e-07 (rank : 720)
Query Neighborhood Hits	1959	Target Neighborhood Hits	831	Shared Neighborhood Hits	807
SwissProt Accessions	P49336	Gene names	CDK8
Domain Architecture
Description	Cell division protein kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Protein kinase K35).

MRCKG_HUMAN
NC score	0.785921 (rank : 486)	θ value	2.13179e-17 (rank : 252)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1519	Shared Neighborhood Hits	878
SwissProt Accessions	Q6DT37, O00565	Gene names	CDC42BPG
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

AAK1_HUMAN
NC score	0.785847 (rank : 487)	θ value	2.44474e-05 (rank : 800)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1077	Shared Neighborhood Hits	926
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

DYR1B_MOUSE
NC score	0.785588 (rank : 488)	θ value	7.34386e-10 (rank : 583)
Query Neighborhood Hits	1959	Target Neighborhood Hits	799	Shared Neighborhood Hits	779
SwissProt Accessions	Q9Z188	Gene names	Dyrk1b
Domain Architecture
Description	Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1).

E2AK4_MOUSE
NC score	0.785581 (rank : 489)	θ value	0.000461057 (rank : 880)
Query Neighborhood Hits	1959	Target Neighborhood Hits	984	Shared Neighborhood Hits	832
SwissProt Accessions	Q9QZ05, Q6GQT4, Q6ZPT5, Q8C5S0, Q8CIF5, Q9CT30, Q9CUV9, Q9ESB6, Q9ESB7, Q9ESB8	Gene names	Eif2ak4, Gcn2, Kiaa1338
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 2-alpha kinase 4 (EC 2.7.11.1) (GCN2-like protein) (mGCN2).

BMP2K_MOUSE
NC score	0.785474 (rank : 490)	θ value	3.19293e-05 (rank : 809)
Query Neighborhood Hits	1959	Target Neighborhood Hits	874	Shared Neighborhood Hits	785
SwissProt Accessions	Q91Z96, Q8C8L7	Gene names	Bmp2k, Bike
Domain Architecture
Description	BMP-2-inducible protein kinase (EC 2.7.11.1) (BIKe).

TAOK3_HUMAN
NC score	0.785066 (rank : 491)	θ value	1.68911e-14 (rank : 403)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1494	Shared Neighborhood Hits	882
SwissProt Accessions	Q9H2K8, Q658N1, Q8IUM4, Q9HC79, Q9NZM9, Q9UHG7	Gene names	TAOK3, DPK, JIK, KDS, MAP3K18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3) (Jun kinase-inhibitory kinase) (JNK/SAPK- inhibitory kinase) (Dendritic cell-derived protein kinase) (Cutaneous T-cell lymphoma tumor antigen HD-CL-09) (CTCL tumor antigen HD-CL-09) (Kinase from chicken homolog A) (hKFC-A).

MRCKG_MOUSE
NC score	0.784679 (rank : 492)	θ value	2.35696e-16 (rank : 302)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1466	Shared Neighborhood Hits	862
SwissProt Accessions	Q80UW5	Gene names	Cdc42bpg
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

GAK_MOUSE
NC score	0.784248 (rank : 493)	θ value	1.06045e-08 (rank : 623)
Query Neighborhood Hits	1959	Target Neighborhood Hits	964	Shared Neighborhood Hits	837
SwissProt Accessions	Q99KY4, Q6P1I8, Q6P9S5, Q8BM74, Q8K0Q4	Gene names	Gak
Domain Architecture	No domain graphic available
Description	Cyclin G-associated kinase (EC 2.7.11.1).

BMP2K_HUMAN
NC score	0.783957 (rank : 494)	θ value	3.19293e-05 (rank : 808)
Query Neighborhood Hits	1959	Target Neighborhood Hits	867	Shared Neighborhood Hits	782
SwissProt Accessions	Q9NSY1, O94791, Q8IYF2, Q8N2G7, Q8NHG9, Q9NTG8	Gene names	BMP2K, BIKE
Domain Architecture
Description	BMP-2-inducible protein kinase (EC 2.7.11.1) (BIKe).

AAK1_MOUSE
NC score	0.783662 (rank : 495)	θ value	2.44474e-05 (rank : 801)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1051	Shared Neighborhood Hits	896
SwissProt Accessions	Q3UHJ0, Q3TY53, Q6ZPZ6, Q80XP6	Gene names	Aak1, Kiaa1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

TESK1_MOUSE
NC score	0.782622 (rank : 496)	θ value	1.63604e-09 (rank : 600)
Query Neighborhood Hits	1959	Target Neighborhood Hits	862	Shared Neighborhood Hits	814
SwissProt Accessions	O70146, O70147	Gene names	Tesk1
Domain Architecture
Description	Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein kinase 1).

DYR1B_HUMAN
NC score	0.781972 (rank : 497)	θ value	7.34386e-10 (rank : 582)
Query Neighborhood Hits	1959	Target Neighborhood Hits	831	Shared Neighborhood Hits	791
SwissProt Accessions	Q9Y463, O75258, O75788, O75789	Gene names	DYRK1B, MIRK
Domain Architecture
Description	Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1) (Mirk protein kinase) (Minibrain-related kinase).

TESK2_HUMAN
NC score	0.781758 (rank : 498)	θ value	6.41864e-14 (rank : 435)
Query Neighborhood Hits	1959	Target Neighborhood Hits	851	Shared Neighborhood Hits	811
SwissProt Accessions	Q96S53, Q8N520, Q9Y3Q6	Gene names	TESK2
Domain Architecture
Description	Dual specificity testis-specific protein kinase 2 (EC 2.7.12.1) (Testicular protein kinase 2).

TESK2_MOUSE
NC score	0.781719 (rank : 499)	θ value	1.86753e-13 (rank : 451)
Query Neighborhood Hits	1959	Target Neighborhood Hits	833	Shared Neighborhood Hits	800
SwissProt Accessions	Q8VCT9	Gene names	Tesk2
Domain Architecture
Description	Dual specificity testis-specific protein kinase 2 (EC 2.7.12.1) (Testicular protein kinase 2).

TESK1_HUMAN
NC score	0.780905 (rank : 500)	θ value	6.87365e-08 (rank : 670)
Query Neighborhood Hits	1959	Target Neighborhood Hits	864	Shared Neighborhood Hits	811
SwissProt Accessions	Q15569	Gene names	TESK1
Domain Architecture
Description	Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein kinase 1).

M3K7_MOUSE
NC score	0.780615 (rank : 501)	θ value	2.0648e-12 (rank : 490)
Query Neighborhood Hits	1959	Target Neighborhood Hits	892	Shared Neighborhood Hits	815
SwissProt Accessions	Q62073	Gene names	Map3k7, Tak1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta- activated kinase 1).

M3K7_HUMAN
NC score	0.780494 (rank : 502)	θ value	2.0648e-12 (rank : 489)
Query Neighborhood Hits	1959	Target Neighborhood Hits	892	Shared Neighborhood Hits	814
SwissProt Accessions	O43318, O43317, O43319, Q5TDN2, Q5TDN3	Gene names	MAP3K7, TAK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta- activated kinase 1).

UHMK1_HUMAN
NC score	0.778527 (rank : 503)	θ value	4.1701e-05 (rank : 820)
Query Neighborhood Hits	1959	Target Neighborhood Hits	808	Shared Neighborhood Hits	766
SwissProt Accessions	Q8TAS1, Q96C22	Gene names	UHMK1, KIS, KIST
Domain Architecture
Description	Serine/threonine-protein kinase Kist (EC 2.7.11.1) (Kinase interacting with stathmin) (U2AF homology motif kinase 1).

IRAK4_MOUSE
NC score	0.778364 (rank : 504)	θ value	3.29651e-10 (rank : 571)
Query Neighborhood Hits	1959	Target Neighborhood Hits	820	Shared Neighborhood Hits	793
SwissProt Accessions	Q8R4K2, Q80WW1	Gene names	Irak4
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1) (IRAK-4).

WEE1_HUMAN
NC score	0.777871 (rank : 505)	θ value	9.92553e-07 (rank : 740)
Query Neighborhood Hits	1959	Target Neighborhood Hits	777	Shared Neighborhood Hits	748
SwissProt Accessions	P30291	Gene names	WEE1
Domain Architecture
Description	Wee1-like protein kinase (EC 2.7.10.2) (Wee1A kinase) (WEE1hu).

DYRK4_HUMAN
NC score	0.777502 (rank : 506)	θ value	1.9326e-10 (rank : 566)
Query Neighborhood Hits	1959	Target Neighborhood Hits	750	Shared Neighborhood Hits	740
SwissProt Accessions	Q9NR20, Q8NEF2, Q92631	Gene names	DYRK4
Domain Architecture	No domain graphic available
Description	Dual specificity tyrosine-phosphorylation-regulated kinase 4 (EC 2.7.12.1).

UHMK1_MOUSE
NC score	0.777265 (rank : 507)	θ value	4.1701e-05 (rank : 821)
Query Neighborhood Hits	1959	Target Neighborhood Hits	809	Shared Neighborhood Hits	766
SwissProt Accessions	P97343, Q61775, Q9CYT1	Gene names	Uhmk1, Kis, Kist
Domain Architecture
Description	Serine/threonine-protein kinase Kist (EC 2.7.11.1) (Kinase interacting with stathmin) (U2AF homology motif kinase 1).

RIPK1_HUMAN
NC score	0.776258 (rank : 508)	θ value	3.29651e-10 (rank : 575)
Query Neighborhood Hits	1959	Target Neighborhood Hits	891	Shared Neighborhood Hits	830
SwissProt Accessions	Q13546, Q13180	Gene names	RIPK1, RIP
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

HIPK3_MOUSE
NC score	0.775978 (rank : 509)	θ value	4.0297e-08 (rank : 660)
Query Neighborhood Hits	1959	Target Neighborhood Hits	857	Shared Neighborhood Hits	802
SwissProt Accessions	Q9ERH7, O88906, Q9QZR2	Gene names	Hipk3, Fist3
Domain Architecture	No domain graphic available
Description	Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Fas- interacting serine/threonine-protein kinase) (FIST) (Nuclear body- associated kinase 3) (Nbak3) (Androgen receptor-interacting nuclear protein kinase) (ANPK).

TAOK1_MOUSE
NC score	0.775731 (rank : 510)	θ value	1.52774e-15 (rank : 340)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1720	Shared Neighborhood Hits	913
SwissProt Accessions	Q5F2E8, Q69ZL2, Q8JZX2, Q91VG7	Gene names	Taok1, Kiaa1361
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1).

TAOK1_HUMAN
NC score	0.775268 (rank : 511)	θ value	1.52774e-15 (rank : 339)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1734	Shared Neighborhood Hits	916
SwissProt Accessions	Q7L7X3, Q96L75, Q9H2K7, Q9H7S5, Q9P2I6	Gene names	TAOK1, KIAA1361, MAP3K16
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1) (STE20-like kinase PSK2) (Kinase from chicken homolog B) (hKFC-B).

HIPK3_HUMAN
NC score	0.774132 (rank : 512)	θ value	4.0297e-08 (rank : 659)
Query Neighborhood Hits	1959	Target Neighborhood Hits	867	Shared Neighborhood Hits	807
SwissProt Accessions	Q9H422, O14632, Q2PBG4, Q2PBG5, Q92632, Q9HAS2	Gene names	HIPK3, DYRK6, FIST3, PKY
Domain Architecture	No domain graphic available
Description	Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Homolog of protein kinase YAK1) (Fas-interacting serine/threonine-protein kinase) (FIST) (Androgen receptor-interacting nuclear protein kinase) (ANPK).

HIPK1_HUMAN
NC score	0.774018 (rank : 513)	θ value	8.11959e-09 (rank : 618)
Query Neighborhood Hits	1959	Target Neighborhood Hits	843	Shared Neighborhood Hits	794
SwissProt Accessions	Q86Z02, O75125, Q8IYD7, Q8NDN5, Q8NEB6, Q8TBZ1	Gene names	HIPK1, KIAA0630
Domain Architecture
Description	Homeodomain-interacting protein kinase 1 (EC 2.7.11.1).

HIPK1_MOUSE
NC score	0.773710 (rank : 514)	θ value	8.11959e-09 (rank : 619)
Query Neighborhood Hits	1959	Target Neighborhood Hits	838	Shared Neighborhood Hits	790
SwissProt Accessions	O88904, Q80TV5, Q9QUQ8, Q9QZR3, Q9WVN7	Gene names	Hipk1, Kiaa0630, Myak, Nbak2
Domain Architecture
Description	Homeodomain-interacting protein kinase 1 (EC 2.7.11.1) (Protein kinase Myak) (Nuclear body-associated kinase 2).

HIPK2_HUMAN
NC score	0.773115 (rank : 515)	θ value	6.21693e-09 (rank : 614)
Query Neighborhood Hits	1959	Target Neighborhood Hits	845	Shared Neighborhood Hits	796
SwissProt Accessions	Q9H2X6, Q75MR7, Q8WWI4, Q9H2Y1	Gene names	HIPK2
Domain Architecture
Description	Homeodomain-interacting protein kinase 2 (EC 2.7.11.1) (hHIPk2).

HIPK2_MOUSE
NC score	0.772496 (rank : 516)	θ value	6.21693e-09 (rank : 615)
Query Neighborhood Hits	1959	Target Neighborhood Hits	871	Shared Neighborhood Hits	803
SwissProt Accessions	Q9QZR5, O88905, Q99P45, Q99P46, Q9D2E6, Q9D474, Q9EQL2, Q9QZR4	Gene names	Hipk2, Nbak1, Stank
Domain Architecture
Description	Homeodomain-interacting protein kinase 2 (EC 2.7.11.1) (Nuclear body- associated kinase 1) (Sialophorin tail-associated nuclear serine/threonine-protein kinase).

IRAK4_HUMAN
NC score	0.772417 (rank : 517)	θ value	8.97725e-08 (rank : 673)
Query Neighborhood Hits	1959	Target Neighborhood Hits	816	Shared Neighborhood Hits	794
SwissProt Accessions	Q9NWZ3, Q8TDF7, Q9Y589	Gene names	IRAK4
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1) (IRAK-4) (NY- REN-64 antigen).

DYR1A_MOUSE
NC score	0.771483 (rank : 518)	θ value	9.59137e-10 (rank : 590)
Query Neighborhood Hits	1959	Target Neighborhood Hits	762	Shared Neighborhood Hits	748
SwissProt Accessions	Q61214	Gene names	Dyrk1a, Dyrk
Domain Architecture
Description	Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.1) (Protein kinase minibrain homolog) (MNBH) (MP86) (Dual specificity YAK1-related kinase).

DYR1A_HUMAN
NC score	0.771481 (rank : 519)	θ value	9.59137e-10 (rank : 589)
Query Neighborhood Hits	1959	Target Neighborhood Hits	764	Shared Neighborhood Hits	749
SwissProt Accessions	Q13627, O60769, Q92582, Q92810, Q9UNM5	Gene names	DYRK1A, DYRK, MNB, MNBH
Domain Architecture
Description	Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.1) (Protein kinase minibrain homolog) (MNBH) (HP86) (Dual specificity YAK1-related kinase).

TRIB2_HUMAN
NC score	0.770981 (rank : 520)	θ value	2.36244e-08 (rank : 648)
Query Neighborhood Hits	1959	Target Neighborhood Hits	657	Shared Neighborhood Hits	649
SwissProt Accessions	Q92519	Gene names	TRIB2, TRB2
Domain Architecture	No domain graphic available
Description	Tribbles homolog 2 (TRB-2).

TRIB2_MOUSE
NC score	0.770443 (rank : 521)	θ value	2.36244e-08 (rank : 649)
Query Neighborhood Hits	1959	Target Neighborhood Hits	653	Shared Neighborhood Hits	645
SwissProt Accessions	Q8K4K3, Q8K017, Q8R2V8	Gene names	Trib2
Domain Architecture	No domain graphic available
Description	Tribbles homolog 2 (TRB-2).

RIPK1_MOUSE
NC score	0.769313 (rank : 522)	θ value	5.62301e-10 (rank : 579)
Query Neighborhood Hits	1959	Target Neighborhood Hits	874	Shared Neighborhood Hits	826
SwissProt Accessions	Q60855, Q3U0J3, Q8CD90	Gene names	Ripk1, Rinp, Rip
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

RAF1_MOUSE
NC score	0.769101 (rank : 523)	θ value	2.43908e-13 (rank : 456)
Query Neighborhood Hits	1959	Target Neighborhood Hits	886	Shared Neighborhood Hits	826
SwissProt Accessions	Q99N57, Q91WH1	Gene names	Raf1, Craf
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

STK10_MOUSE
NC score	0.768851 (rank : 524)	θ value	2.60593e-15 (rank : 355)
Query Neighborhood Hits	1959	Target Neighborhood Hits	2132	Shared Neighborhood Hits	981
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

RAF1_HUMAN
NC score	0.768644 (rank : 525)	θ value	2.43908e-13 (rank : 455)
Query Neighborhood Hits	1959	Target Neighborhood Hits	886	Shared Neighborhood Hits	823
SwissProt Accessions	P04049	Gene names	RAF1, RAF
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

BRAF1_HUMAN
NC score	0.767759 (rank : 526)	θ value	5.08577e-11 (rank : 543)
Query Neighborhood Hits	1959	Target Neighborhood Hits	883	Shared Neighborhood Hits	818
SwissProt Accessions	P15056, Q13878, Q9Y6T3	Gene names	BRAF, BRAF1, RAFB1
Domain Architecture
Description	B-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1).

M3K11_HUMAN
NC score	0.766594 (rank : 527)	θ value	2.28291e-11 (rank : 532)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1136	Shared Neighborhood Hits	896
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

PTK7_HUMAN
NC score	0.766238 (rank : 528)	θ value	1.92812e-18 (rank : 218)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1103	Shared Neighborhood Hits	998
SwissProt Accessions	Q13308, Q13417	Gene names	PTK7, CCK4
Domain Architecture
Description	Tyrosine-protein kinase-like 7 precursor (Colon carcinoma kinase 4) (CCK-4).

M3K9_HUMAN
NC score	0.765521 (rank : 529)	θ value	4.59992e-12 (rank : 507)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1123	Shared Neighborhood Hits	871
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

PRP4B_HUMAN
NC score	0.765489 (rank : 530)	θ value	7.34386e-10 (rank : 586)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1030	Shared Neighborhood Hits	818
SwissProt Accessions	Q13523, Q8TDP2, Q96QT7, Q9UEE6	Gene names	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (PRP4 kinase).

M3K10_HUMAN
NC score	0.765378 (rank : 531)	θ value	6.41864e-14 (rank : 432)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1071	Shared Neighborhood Hits	837
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

ARAF_HUMAN
NC score	0.765288 (rank : 532)	θ value	1.42992e-13 (rank : 446)
Query Neighborhood Hits	1959	Target Neighborhood Hits	924	Shared Neighborhood Hits	834
SwissProt Accessions	P10398, P07557, Q5H9B3	Gene names	ARAF, ARAF1, PKS, PKS2
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (A- raf-1) (Proto-oncogene Pks).

MOS_MOUSE
NC score	0.764944 (rank : 533)	θ value	1.133e-10 (rank : 559)
Query Neighborhood Hits	1959	Target Neighborhood Hits	833	Shared Neighborhood Hits	813
SwissProt Accessions	P00536	Gene names	Mos
Domain Architecture	No domain graphic available
Description	Proto-oncogene serine/threonine-protein kinase mos (EC 2.7.11.1) (c- mos) (Oocyte maturation factor mos).

ARAF_MOUSE
NC score	0.764867 (rank : 534)	θ value	6.41864e-14 (rank : 431)
Query Neighborhood Hits	1959	Target Neighborhood Hits	874	Shared Neighborhood Hits	819
SwissProt Accessions	P04627, Q99J44, Q9CTT5, Q9D6R6, Q9DBU7	Gene names	Araf, A-raf, Araf1
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1).

MOS_HUMAN
NC score	0.764380 (rank : 535)	θ value	1.80886e-08 (rank : 637)
Query Neighborhood Hits	1959	Target Neighborhood Hits	829	Shared Neighborhood Hits	812
SwissProt Accessions	P00540	Gene names	MOS
Domain Architecture
Description	Proto-oncogene serine/threonine-protein kinase mos (EC 2.7.11.1) (c- mos) (Oocyte maturation factor mos).

PRP4B_MOUSE
NC score	0.763483 (rank : 536)	θ value	7.34386e-10 (rank : 587)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1040	Shared Neighborhood Hits	816
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

MLTK_HUMAN
NC score	0.763119 (rank : 537)	θ value	2.98157e-11 (rank : 535)
Query Neighborhood Hits	1959	Target Neighborhood Hits	911	Shared Neighborhood Hits	826
SwissProt Accessions	Q9NYL2, Q53SX1, Q580W8, Q59GY5, Q86YW8, Q9HCC4, Q9HCC5, Q9HDD2, Q9NYE9	Gene names	MLTK, ZAK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Cervical cancer suppressor gene 4 protein).

MLTK_MOUSE
NC score	0.763094 (rank : 538)	θ value	8.67504e-11 (rank : 555)
Query Neighborhood Hits	1959	Target Neighborhood Hits	874	Shared Neighborhood Hits	812
SwissProt Accessions	Q9ESL4, Q3V1X8, Q8BR73, Q9ESL3	Gene names	Mltk
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif kinase ZAK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK).

CLK1_MOUSE
NC score	0.760622 (rank : 539)	θ value	5.81887e-07 (rank : 721)
Query Neighborhood Hits	1959	Target Neighborhood Hits	760	Shared Neighborhood Hits	749
SwissProt Accessions	P22518	Gene names	Clk1, Clk, Sty
Domain Architecture
Description	Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1) (Protein kinase STY).

CLK1_HUMAN
NC score	0.760449 (rank : 540)	θ value	7.59969e-07 (rank : 729)
Query Neighborhood Hits	1959	Target Neighborhood Hits	756	Shared Neighborhood Hits	741
SwissProt Accessions	P49759	Gene names	CLK1, CLK
Domain Architecture
Description	Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1).

WEE1B_HUMAN
NC score	0.760313 (rank : 541)	θ value	2.88788e-06 (rank : 765)
Query Neighborhood Hits	1959	Target Neighborhood Hits	836	Shared Neighborhood Hits	760
SwissProt Accessions	P0C1S8	Gene names	WEE1B, WEE2
Domain Architecture	No domain graphic available
Description	Wee1-like protein kinase 1B (EC 2.7.10.2) (Wee1B kinase).

WEE1B_MOUSE
NC score	0.758041 (rank : 542)	θ value	2.61198e-07 (rank : 701)
Query Neighborhood Hits	1959	Target Neighborhood Hits	765	Shared Neighborhood Hits	736
SwissProt Accessions	Q66JT0, Q4U4S4, Q7TPV9	Gene names	Wee1b, Wee2
Domain Architecture	No domain graphic available
Description	Wee1-like protein kinase 1B (EC 2.7.10.2) (Wee1B kinase) (mWee1B).

CLK4_HUMAN
NC score	0.756087 (rank : 543)	θ value	1.29631e-06 (rank : 744)
Query Neighborhood Hits	1959	Target Neighborhood Hits	759	Shared Neighborhood Hits	746
SwissProt Accessions	Q9HAZ1	Gene names	CLK4
Domain Architecture
Description	Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4).

CLK4_MOUSE
NC score	0.754958 (rank : 544)	θ value	7.59969e-07 (rank : 730)
Query Neighborhood Hits	1959	Target Neighborhood Hits	759	Shared Neighborhood Hits	745
SwissProt Accessions	O35493, O35721, Q8CEU9, Q99LU6	Gene names	Clk4
Domain Architecture
Description	Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4).

RIPK3_MOUSE
NC score	0.754548 (rank : 545)	θ value	0.00102713 (rank : 919)
Query Neighborhood Hits	1959	Target Neighborhood Hits	867	Shared Neighborhood Hits	814
SwissProt Accessions	Q9QZL0	Gene names	Ripk3, Rip3
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (mRIP3).

M3KL4_HUMAN
NC score	0.753731 (rank : 546)	θ value	4.76016e-09 (rank : 607)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1087	Shared Neighborhood Hits	832
SwissProt Accessions	Q5TCX8, Q5TCX7, Q5TCX9, Q8WWN1, Q8WWN2, Q96JM1	Gene names	MLK4, KIAA1804
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase 4).

CLK2_HUMAN
NC score	0.752000 (rank : 547)	θ value	1.38499e-08 (rank : 626)
Query Neighborhood Hits	1959	Target Neighborhood Hits	752	Shared Neighborhood Hits	736
SwissProt Accessions	P49760, Q96CQ0	Gene names	CLK2
Domain Architecture
Description	Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2).

FGFR1_MOUSE
NC score	0.751720 (rank : 548)	θ value	7.34386e-10 (rank : 584)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1068	Shared Neighborhood Hits	1010
SwissProt Accessions	P16092, Q01736, Q61562, Q80T10	Gene names	Fgfr1, Flg
Domain Architecture
Description	Basic fibroblast growth factor receptor 1 precursor (EC 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) (CD331 antigen).

FGFR1_HUMAN
NC score	0.751608 (rank : 549)	θ value	2.79066e-09 (rank : 601)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1069	Shared Neighborhood Hits	1012
SwissProt Accessions	P11362, P17049, Q02063, Q02065, Q14306, Q14307, Q8N685	Gene names	FGFR1, FGFBR, FLG, FLT2
Domain Architecture
Description	Basic fibroblast growth factor receptor 1 precursor (EC 2.7.10.1) (FGFR-1) (bFGF-R) (Fms-like tyrosine kinase 2) (c-fgr) (CD331 antigen).

LIMK2_HUMAN
NC score	0.750955 (rank : 550)	θ value	3.41135e-07 (rank : 707)
Query Neighborhood Hits	1959	Target Neighborhood Hits	986	Shared Neighborhood Hits	813
SwissProt Accessions	P53671, Q7KZ80, Q96E10, Q99464	Gene names	LIMK2
Domain Architecture
Description	LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2).

RIPK3_HUMAN
NC score	0.750845 (rank : 551)	θ value	7.1131e-05 (rank : 836)
Query Neighborhood Hits	1959	Target Neighborhood Hits	828	Shared Neighborhood Hits	797
SwissProt Accessions	Q9Y572	Gene names	RIPK3, RIP3
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3).

LIMK1_HUMAN
NC score	0.748384 (rank : 552)	θ value	1.63604e-09 (rank : 598)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1005	Shared Neighborhood Hits	819
SwissProt Accessions	P53667, O15283, Q15820, Q15821, Q75MU3, Q9Y5Q1	Gene names	LIMK1, LIMK
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1).

FGFR2_HUMAN
NC score	0.748333 (rank : 553)	θ value	1.38499e-08 (rank : 628)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1062	Shared Neighborhood Hits	996
SwissProt Accessions	P21802, P18443, Q01742, Q12922, Q14300, Q14301, Q14302, Q14303, Q14304, Q14305, Q14672, Q14718, Q14719, Q86YI4, Q96KL9, Q96KM0, Q96KM1, Q96KM2, Q9NZU2, Q9NZU3, Q9UD01, Q9UD02, Q9UIH3, Q9UIH4, Q9UIH5, Q9UIH6, Q9UIH7, Q9UIH8, Q9UM87, Q9UMC6, Q9UNS7, Q9UQH7, Q9UQH8, Q9UQH9, Q9UQI0	Gene names	FGFR2, BEK, KSAM
Domain Architecture
Description	Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor 2) (CD332 antigen).

LIMK2_MOUSE
NC score	0.748293 (rank : 554)	θ value	4.45536e-07 (rank : 715)
Query Neighborhood Hits	1959	Target Neighborhood Hits	998	Shared Neighborhood Hits	812
SwissProt Accessions	O54785, O54776, O55238, Q9QUL4	Gene names	Limk2
Domain Architecture
Description	LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2).

LIMK1_MOUSE
NC score	0.747489 (rank : 555)	θ value	2.36244e-08 (rank : 644)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1008	Shared Neighborhood Hits	817
SwissProt Accessions	P53668	Gene names	Limk1, Limk
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (KIZ-1).

KSR2_HUMAN
NC score	0.747382 (rank : 556)	θ value	9.29e-05 (rank : 840)
Query Neighborhood Hits	1959	Target Neighborhood Hits	920	Shared Neighborhood Hits	843
SwissProt Accessions	Q6VAB6, Q8N775	Gene names	KSR2
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-2 (hKSR2).

FGFR2_MOUSE
NC score	0.744960 (rank : 557)	θ value	6.87365e-08 (rank : 667)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1062	Shared Neighborhood Hits	994
SwissProt Accessions	P21803, O55141, Q00389, Q61342	Gene names	Fgfr2, Bek, Ect1
Domain Architecture
Description	Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor) (CD332 antigen).

TRIB1_HUMAN
NC score	0.743451 (rank : 558)	θ value	1.53129e-07 (rank : 686)
Query Neighborhood Hits	1959	Target Neighborhood Hits	598	Shared Neighborhood Hits	585
SwissProt Accessions	Q96RU8, O15180, Q9H2Y8	Gene names	TRIB1, C8FW, GIG2, TRB1
Domain Architecture	No domain graphic available
Description	Tribbles homolog 1 (TRB-1) (SKIP1) (G-protein-coupled receptor-induced protein 2) (GIG-2).

TRIB1_MOUSE
NC score	0.742171 (rank : 559)	θ value	1.99992e-07 (rank : 693)
Query Neighborhood Hits	1959	Target Neighborhood Hits	593	Shared Neighborhood Hits	584
SwissProt Accessions	Q8K4K4, Q8BFS7, Q8BJR9, Q8BZX3, Q91W04	Gene names	Trib1, Trb1
Domain Architecture	No domain graphic available
Description	Tribbles homolog 1 (TRB-1).

FGFR3_MOUSE
NC score	0.741812 (rank : 560)	θ value	7.59969e-07 (rank : 733)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1059	Shared Neighborhood Hits	1002
SwissProt Accessions	Q61851, Q61564, Q63834	Gene names	Fgfr3, Mfr3, Sam3
Domain Architecture
Description	Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1) (FGFR-3) (Heparin-binding growth factor receptor) (CD333 antigen).

FGFR3_HUMAN
NC score	0.741399 (rank : 561)	θ value	1.53129e-07 (rank : 681)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1042	Shared Neighborhood Hits	996
SwissProt Accessions	P22607, Q14308, Q16294, Q16608	Gene names	FGFR3, JTK4
Domain Architecture
Description	Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1) (FGFR-3) (CD333 antigen).

CLK2_MOUSE
NC score	0.739897 (rank : 562)	θ value	8.97725e-08 (rank : 672)
Query Neighborhood Hits	1959	Target Neighborhood Hits	743	Shared Neighborhood Hits	730
SwissProt Accessions	O35491	Gene names	Clk2
Domain Architecture
Description	Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2).

ROCK2_HUMAN
NC score	0.738120 (rank : 563)	θ value	6.20254e-17 (rank : 275)
Query Neighborhood Hits	1959	Target Neighborhood Hits	2073	Shared Neighborhood Hits	916
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

MUSK_HUMAN
NC score	0.736245 (rank : 564)	θ value	6.62687e-19 (rank : 199)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1074	Shared Neighborhood Hits	1002
SwissProt Accessions	O15146	Gene names	MUSK
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (Muscle-specific kinase receptor) (MuSK).

MRCKA_HUMAN
NC score	0.736201 (rank : 565)	θ value	1.058e-16 (rank : 285)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1999	Shared Neighborhood Hits	901
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

JAK2_HUMAN
NC score	0.734763 (rank : 566)	θ value	3.89403e-11 (rank : 537)
Query Neighborhood Hits	1959	Target Neighborhood Hits	847	Shared Neighborhood Hits	811
SwissProt Accessions	O60674, O14636, O75297	Gene names	JAK2
Domain Architecture
Description	Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2).

JAK2_MOUSE
NC score	0.734041 (rank : 567)	θ value	6.64225e-11 (rank : 550)
Query Neighborhood Hits	1959	Target Neighborhood Hits	839	Shared Neighborhood Hits	806
SwissProt Accessions	Q62120, Q62124	Gene names	Jak2
Domain Architecture
Description	Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2).

CTRO_HUMAN
NC score	0.734024 (rank : 568)	θ value	2.20605e-14 (rank : 407)
Query Neighborhood Hits	1959	Target Neighborhood Hits	2092	Shared Neighborhood Hits	941
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

FGFR4_HUMAN
NC score	0.733870 (rank : 569)	θ value	4.92598e-06 (rank : 771)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1037	Shared Neighborhood Hits	995
SwissProt Accessions	P22455, O43785, Q14309	Gene names	FGFR4, JTK2, TKF
Domain Architecture
Description	Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1) (FGFR-4) (CD334 antigen).

ROCK1_HUMAN
NC score	0.733702 (rank : 570)	θ value	9.56915e-18 (rank : 239)
Query Neighborhood Hits	1959	Target Neighborhood Hits	2000	Shared Neighborhood Hits	914
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

MUSK_MOUSE
NC score	0.733086 (rank : 571)	θ value	5.60996e-18 (rank : 230)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1057	Shared Neighborhood Hits	992
SwissProt Accessions	Q61006, Q61005, Q61987, Q61988	Gene names	Musk, Nsk2
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific kinase receptor) (MuSK).

JAK3_MOUSE
NC score	0.732243 (rank : 572)	θ value	1.99992e-07 (rank : 690)
Query Neighborhood Hits	1959	Target Neighborhood Hits	821	Shared Neighborhood Hits	795
SwissProt Accessions	Q62137, Q61746, Q61747	Gene names	Jak3
Domain Architecture
Description	Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3).

ROCK2_MOUSE
NC score	0.731228 (rank : 573)	θ value	1.058e-16 (rank : 287)
Query Neighborhood Hits	1959	Target Neighborhood Hits	2072	Shared Neighborhood Hits	911
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

TRIB3_MOUSE
NC score	0.731044 (rank : 574)	θ value	5.81887e-07 (rank : 727)
Query Neighborhood Hits	1959	Target Neighborhood Hits	578	Shared Neighborhood Hits	571
SwissProt Accessions	Q8K4K2, Q3UMQ0, Q921E7	Gene names	Trib3, Nipk, Trb3
Domain Architecture
Description	Tribbles homolog 3 (TRB-3) (Neuronal cell death-inducible putative kinase).

PINK1_MOUSE
NC score	0.729894 (rank : 575)	θ value	5.44631e-05 (rank : 830)
Query Neighborhood Hits	1959	Target Neighborhood Hits	726	Shared Neighborhood Hits	712
SwissProt Accessions	Q99MQ3, Q7TMZ3, Q811I8, Q91XU5	Gene names	Pink1
Domain Architecture
Description	Serine/threonine-protein kinase PINK1, mitochondrial precursor (EC 2.7.11.1) (PTEN-induced putative kinase protein 1) (BRPK).

MYO3A_MOUSE
NC score	0.729670 (rank : 576)	θ value	1.68911e-14 (rank : 402)
Query Neighborhood Hits	1959	Target Neighborhood Hits	902	Shared Neighborhood Hits	820
SwissProt Accessions	Q8K3H5	Gene names	Myo3a
Domain Architecture
Description	Myosin IIIA (EC 2.7.11.1).

CLK3_HUMAN
NC score	0.728992 (rank : 577)	θ value	1.43324e-05 (rank : 786)
Query Neighborhood Hits	1959	Target Neighborhood Hits	748	Shared Neighborhood Hits	730
SwissProt Accessions	P49761, Q9BRS3, Q9BUJ7	Gene names	CLK3
Domain Architecture
Description	Dual specificity protein kinase CLK3 (EC 2.7.12.1) (CDC-like kinase 3).

CLK3_MOUSE
NC score	0.728341 (rank : 578)	θ value	1.43324e-05 (rank : 787)
Query Neighborhood Hits	1959	Target Neighborhood Hits	761	Shared Neighborhood Hits	732
SwissProt Accessions	O35492	Gene names	Clk3
Domain Architecture
Description	Dual specificity protein kinase CLK3 (EC 2.7.12.1) (CDC-like kinase 3).

NTRK2_HUMAN
NC score	0.728052 (rank : 579)	θ value	9.59137e-10 (rank : 592)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1081	Shared Neighborhood Hits	963
SwissProt Accessions	Q16620, Q16675, Q8WXJ6	Gene names	NTRK2, TRKB
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB) (Trk-B).

NTRK2_MOUSE
NC score	0.728036 (rank : 580)	θ value	9.59137e-10 (rank : 593)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1088	Shared Neighborhood Hits	961
SwissProt Accessions	P15209, Q3TUF9, Q80WU0, Q91XJ9	Gene names	Ntrk2, Trkb
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B).

TYK2_HUMAN
NC score	0.727412 (rank : 581)	θ value	2.36244e-08 (rank : 650)
Query Neighborhood Hits	1959	Target Neighborhood Hits	841	Shared Neighborhood Hits	813
SwissProt Accessions	P29597, Q6QB10, Q96CH0	Gene names	TYK2
Domain Architecture
Description	Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2).

JAK3_HUMAN
NC score	0.727177 (rank : 582)	θ value	2.52405e-10 (rank : 568)
Query Neighborhood Hits	1959	Target Neighborhood Hits	827	Shared Neighborhood Hits	802
SwissProt Accessions	P52333, Q13259, Q13260, Q13611, Q9Y6S2	Gene names	JAK3
Domain Architecture
Description	Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK).

PINK1_HUMAN
NC score	0.725681 (rank : 583)	θ value	2.44474e-05 (rank : 804)
Query Neighborhood Hits	1959	Target Neighborhood Hits	741	Shared Neighborhood Hits	717
SwissProt Accessions	Q9BXM7, Q8N6T9, Q8NBU3, Q96DE4	Gene names	PINK1
Domain Architecture
Description	Serine/threonine-protein kinase PINK1, mitochondrial precursor (EC 2.7.11.1) (PTEN-induced putative kinase protein 1) (BRPK).

VGFR1_MOUSE
NC score	0.725170 (rank : 584)	θ value	2.60593e-15 (rank : 356)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1118	Shared Neighborhood Hits	1016
SwissProt Accessions	P35969, O55094, Q61517	Gene names	Flt1, Emrk2, Flt
Domain Architecture
Description	Vascular endothelial growth factor receptor 1 precursor (EC 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) (Embryonic receptor kinase 2).

MRCKB_MOUSE
NC score	0.724636 (rank : 585)	θ value	2.7842e-17 (rank : 257)
Query Neighborhood Hits	1959	Target Neighborhood Hits	2180	Shared Neighborhood Hits	946
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

AL2S2_HUMAN
NC score	0.723483 (rank : 586)	θ value	0.163984 (rank : 1134)
Query Neighborhood Hits	1959	Target Neighborhood Hits	727	Shared Neighborhood Hits	701
SwissProt Accessions	Q9C0K7, Q5BKY7, Q9P1L0	Gene names	ALS2CR2, ILPIP
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ALS2CR2 (EC 2.7.11.1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein) (ILP- interacting protein) (CALS-21).

TYK2_MOUSE
NC score	0.723047 (rank : 587)	θ value	5.26297e-08 (rank : 664)
Query Neighborhood Hits	1959	Target Neighborhood Hits	850	Shared Neighborhood Hits	816
SwissProt Accessions	Q9R117, O88431, Q8VE41	Gene names	Tyk2
Domain Architecture
Description	Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2).

MYO3A_HUMAN
NC score	0.722415 (rank : 588)	θ value	1.2105e-12 (rank : 478)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1033	Shared Neighborhood Hits	838
SwissProt Accessions	Q8NEV4, Q8WX17, Q9NYS8	Gene names	MYO3A
Domain Architecture
Description	Myosin IIIA (EC 2.7.11.1).

KSR1_MOUSE
NC score	0.721060 (rank : 589)	θ value	0.000158464 (rank : 857)
Query Neighborhood Hits	1959	Target Neighborhood Hits	870	Shared Neighborhood Hits	807
SwissProt Accessions	Q61097, Q61648, Q78DX8	Gene names	Ksr1, Ksr
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras) (mKSR1) (Hb protein).

VGFR1_HUMAN
NC score	0.720242 (rank : 590)	θ value	1.99529e-15 (rank : 350)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1109	Shared Neighborhood Hits	1017
SwissProt Accessions	P17948, O60722, P16057, Q12954	Gene names	FLT1, FLT, FRT
Domain Architecture
Description	Vascular endothelial growth factor receptor 1 precursor (EC 2.7.10.1) (VEGFR-1) (Vascular permeability factor receptor) (Tyrosine-protein kinase receptor FLT) (Flt-1) (Tyrosine-protein kinase FRT) (Fms-like tyrosine kinase 1).

ROCK1_MOUSE
NC score	0.719094 (rank : 591)	θ value	9.56915e-18 (rank : 240)
Query Neighborhood Hits	1959	Target Neighborhood Hits	2126	Shared Neighborhood Hits	925
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

MYO3B_HUMAN
NC score	0.717747 (rank : 592)	θ value	1.99529e-15 (rank : 348)
Query Neighborhood Hits	1959	Target Neighborhood Hits	923	Shared Neighborhood Hits	838
SwissProt Accessions	Q8WXR4, Q8IX64, Q8IX65, Q8IX66, Q8IX67, Q8IX68	Gene names	MYO3B
Domain Architecture
Description	Myosin IIIB (EC 2.7.11.1).

MRCKB_HUMAN
NC score	0.717134 (rank : 593)	θ value	1.058e-16 (rank : 286)
Query Neighborhood Hits	1959	Target Neighborhood Hits	2239	Shared Neighborhood Hits	960
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

JAK1_HUMAN
NC score	0.716975 (rank : 594)	θ value	2.36244e-08 (rank : 643)
Query Neighborhood Hits	1959	Target Neighborhood Hits	858	Shared Neighborhood Hits	811
SwissProt Accessions	P23458	Gene names	JAK1, JAK1A
Domain Architecture
Description	Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1).

LRRK1_HUMAN
NC score	0.715513 (rank : 595)	θ value	5.81887e-07 (rank : 723)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1237	Shared Neighborhood Hits	832
SwissProt Accessions	Q38SD2, Q6NVH5, Q6NYC0, Q6ZNL9, Q6ZNM9, Q96JN5, Q9H5S3	Gene names	LRRK1, KIAA1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

FGFR4_MOUSE
NC score	0.715085 (rank : 596)	θ value	4.45536e-07 (rank : 714)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1026	Shared Neighborhood Hits	983
SwissProt Accessions	Q03142, Q5J7D9, Q8C3V5, Q8CIB8	Gene names	Fgfr4, Fgfr-4, Mpk-11
Domain Architecture
Description	Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1) (FGFR-4) (Protein-tyrosine kinase receptor MPK-11) (CD334 antigen).

FES_MOUSE
NC score	0.714657 (rank : 597)	θ value	3.08544e-08 (rank : 652)
Query Neighborhood Hits	1959	Target Neighborhood Hits	980	Shared Neighborhood Hits	812
SwissProt Accessions	P16879, Q62122	Gene names	Fes, Fps
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

LRRK1_MOUSE
NC score	0.713765 (rank : 598)	θ value	1.53129e-07 (rank : 682)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1267	Shared Neighborhood Hits	838
SwissProt Accessions	Q3UHC2, Q3U476, Q66JQ4, Q6GQR9, Q6NZF5, Q6ZPI4, Q8BKP3, Q8BU93, Q8BUY0, Q8BVV2, Q8R085	Gene names	Lrrk1, Kiaa1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

FES_HUMAN
NC score	0.713643 (rank : 599)	θ value	1.63604e-09 (rank : 597)
Query Neighborhood Hits	1959	Target Neighborhood Hits	978	Shared Neighborhood Hits	802
SwissProt Accessions	P07332	Gene names	FES, FPS
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

CTRO_MOUSE
NC score	0.713633 (rank : 600)	θ value	7.84624e-12 (rank : 518)
Query Neighborhood Hits	1959	Target Neighborhood Hits	2344	Shared Neighborhood Hits	967
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

KSR1_HUMAN
NC score	0.711990 (rank : 601)	θ value	9.29e-05 (rank : 839)
Query Neighborhood Hits	1959	Target Neighborhood Hits	867	Shared Neighborhood Hits	794
SwissProt Accessions	Q8IVT5, Q13476	Gene names	KSR1, KSR
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras).

AL2S2_MOUSE
NC score	0.711061 (rank : 602)	θ value	θ > 10 (rank : 1963)
Query Neighborhood Hits	1959	Target Neighborhood Hits	709	Shared Neighborhood Hits	685
SwissProt Accessions	Q8K4T3, Q6P922, Q8BU86, Q8BXK0, Q8K4T2	Gene names	Als2cr2, Papk
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ALS2CR2 (EC 2.7.11.1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein homolog) (ILP-interacting protein homolog) (Polyploidy-associated protein kinase).

VGFR2_HUMAN
NC score	0.710842 (rank : 603)	θ value	2.60593e-15 (rank : 357)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1103	Shared Neighborhood Hits	1005
SwissProt Accessions	P35968, O60723, Q14178	Gene names	KDR, FLK1
Domain Architecture
Description	Vascular endothelial growth factor receptor 2 precursor (EC 2.7.10.1) (VEGFR-2) (Kinase insert domain receptor) (Protein-tyrosine kinase receptor Flk-1) (CD309 antigen).

TRIB3_HUMAN
NC score	0.710691 (rank : 604)	θ value	3.08544e-08 (rank : 656)
Query Neighborhood Hits	1959	Target Neighborhood Hits	519	Shared Neighborhood Hits	513
SwissProt Accessions	Q96RU7, Q53GU4, Q53ZW7, Q6I9Y9, Q8TAI6, Q9H5M8, Q9NUD2	Gene names	TRIB3, C20orf97, NIPK, SKIP3, TRB3
Domain Architecture
Description	Tribbles homolog 3 (TRB-3) (Neuronal cell death-inducible putative kinase) (p65-interacting inhibitor of NF-kappaB) (SINK).

VGFR2_MOUSE
NC score	0.710198 (rank : 605)	θ value	3.29651e-10 (rank : 576)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1089	Shared Neighborhood Hits	999
SwissProt Accessions	P35918	Gene names	Kdr, Flk-1, Flk1
Domain Architecture
Description	Vascular endothelial growth factor receptor 2 precursor (EC 2.7.10.1) (VEGFR-2) (Protein-tyrosine kinase receptor flk-1) (Fetal liver kinase 1) (Kinase NYK) (CD309 antigen).

JAK1_MOUSE
NC score	0.709528 (rank : 606)	θ value	9.92553e-07 (rank : 736)
Query Neighborhood Hits	1959	Target Neighborhood Hits	854	Shared Neighborhood Hits	809
SwissProt Accessions	P52332, Q62126	Gene names	Jak1
Domain Architecture
Description	Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1).

PTK6_HUMAN
NC score	0.709376 (rank : 607)	θ value	7.59969e-07 (rank : 735)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1020	Shared Neighborhood Hits	819
SwissProt Accessions	Q13882	Gene names	PTK6, BRK
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK).

ROR1_MOUSE
NC score	0.708069 (rank : 608)	θ value	5.81887e-07 (rank : 726)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1025	Shared Neighborhood Hits	968
SwissProt Accessions	Q9Z139	Gene names	Ror1, Ntrkr1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1) (mROR1).

PTK6_MOUSE
NC score	0.707772 (rank : 609)	θ value	1.80886e-08 (rank : 638)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1026	Shared Neighborhood Hits	821
SwissProt Accessions	Q64434	Gene names	Ptk6, Sik
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related intestinal kinase).

ROR1_HUMAN
NC score	0.706523 (rank : 610)	θ value	9.92553e-07 (rank : 737)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1018	Shared Neighborhood Hits	961
SwissProt Accessions	Q01973, Q92776	Gene names	ROR1, NTRKR1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1).

TYRO3_HUMAN
NC score	0.705999 (rank : 611)	θ value	0.000158464 (rank : 860)
Query Neighborhood Hits	1959	Target Neighborhood Hits	995	Shared Neighborhood Hits	939
SwissProt Accessions	Q06418, O14953, Q86VR3	Gene names	TYRO3, BYK, DTK, RSE, SKY
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine- protein kinase DTK) (Protein-tyrosine kinase byk).

TYRO3_MOUSE
NC score	0.704737 (rank : 612)	θ value	0.000158464 (rank : 861)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1007	Shared Neighborhood Hits	944
SwissProt Accessions	P55144, O09070, O09080, P70285, Q60752, Q62482, Q62483, Q62484, Q78E85, Q78E87	Gene names	Tyro3, Dtk, Rse
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase DTK) (TK19-2) (Etk2/tyro3).

LRRK2_HUMAN
NC score	0.701645 (rank : 613)	θ value	2.52405e-10 (rank : 569)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1382	Shared Neighborhood Hits	846
SwissProt Accessions	Q5S007, Q6ZS50, Q8NCX9	Gene names	LRRK2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin).

RIPK2_HUMAN
NC score	0.701158 (rank : 614)	θ value	3.19293e-05 (rank : 811)
Query Neighborhood Hits	1959	Target Neighborhood Hits	774	Shared Neighborhood Hits	741
SwissProt Accessions	O43353, Q6UWF0	Gene names	RIPK2, CARDIAK, RICK, RIP2
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (CARD-containing interleukin-1 beta-converting enzyme- associated kinase) (CARD-containing IL-1 beta ICE-kinase).

TEC_MOUSE
NC score	0.700543 (rank : 615)	θ value	1.02475e-11 (rank : 524)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1006	Shared Neighborhood Hits	813
SwissProt Accessions	P24604, Q9R1M9, Q9WVN0, Q9WVN1, Q9WVN2, Q9WVN3	Gene names	Tec
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

KSYK_MOUSE
NC score	0.699549 (rank : 616)	θ value	1.69304e-06 (rank : 754)
Query Neighborhood Hits	1959	Target Neighborhood Hits	944	Shared Neighborhood Hits	820
SwissProt Accessions	P48025	Gene names	Syk
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

KSYK_HUMAN
NC score	0.699198 (rank : 617)	θ value	2.88788e-06 (rank : 763)
Query Neighborhood Hits	1959	Target Neighborhood Hits	901	Shared Neighborhood Hits	799
SwissProt Accessions	P43405	Gene names	SYK
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

ZAP70_HUMAN
NC score	0.699039 (rank : 618)	θ value	9.92553e-07 (rank : 742)
Query Neighborhood Hits	1959	Target Neighborhood Hits	893	Shared Neighborhood Hits	804
SwissProt Accessions	P43403	Gene names	ZAP70, SRK
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

RIPK2_MOUSE
NC score	0.698763 (rank : 619)	θ value	3.19293e-05 (rank : 812)
Query Neighborhood Hits	1959	Target Neighborhood Hits	776	Shared Neighborhood Hits	740
SwissProt Accessions	P58801	Gene names	Ripk2
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1).

FAK1_HUMAN
NC score	0.698051 (rank : 620)	θ value	5.08577e-11 (rank : 545)
Query Neighborhood Hits	1959	Target Neighborhood Hits	850	Shared Neighborhood Hits	806
SwissProt Accessions	Q05397, Q14291, Q9UD85	Gene names	PTK2, FAK, FAK1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK) (Protein- tyrosine kinase 2).

FAK1_MOUSE
NC score	0.697660 (rank : 621)	θ value	5.08577e-11 (rank : 546)
Query Neighborhood Hits	1959	Target Neighborhood Hits	850	Shared Neighborhood Hits	805
SwissProt Accessions	P34152, O08578	Gene names	Ptk2, Fadk, Fak, Fak1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK).

NTRK3_HUMAN
NC score	0.697262 (rank : 622)	θ value	4.1701e-05 (rank : 816)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1115	Shared Neighborhood Hits	947
SwissProt Accessions	Q16288, Q12827, Q16289	Gene names	NTRK3, TRKC
Domain Architecture
Description	NT-3 growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C).

ZAP70_MOUSE
NC score	0.697198 (rank : 623)	θ value	1.43324e-05 (rank : 795)
Query Neighborhood Hits	1959	Target Neighborhood Hits	905	Shared Neighborhood Hits	809
SwissProt Accessions	P43404	Gene names	Zap70, Srk, Zap-70
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

ROR2_HUMAN
NC score	0.696924 (rank : 624)	θ value	2.36244e-08 (rank : 647)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1014	Shared Neighborhood Hits	949
SwissProt Accessions	Q01974, Q59GF5, Q5SPI5, Q9HAY7, Q9HB61	Gene names	ROR2, NTRKR2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2).

TEC_HUMAN
NC score	0.695506 (rank : 625)	θ value	1.02475e-11 (rank : 523)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1006	Shared Neighborhood Hits	816
SwissProt Accessions	P42680	Gene names	TEC, PSCTK4
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

CSK_MOUSE
NC score	0.695445 (rank : 626)	θ value	6.87365e-08 (rank : 665)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1009	Shared Neighborhood Hits	820
SwissProt Accessions	P41241, Q03143	Gene names	Csk
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase MPK-2) (p50CSK).

FER_HUMAN
NC score	0.695152 (rank : 627)	θ value	6.87365e-08 (rank : 666)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1278	Shared Neighborhood Hits	811
SwissProt Accessions	P16591	Gene names	FER, TYK3
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2) (p94-FER) (c- FER).

RPKL1_MOUSE
NC score	0.694953 (rank : 628)	θ value	0.00228821 (rank : 948)
Query Neighborhood Hits	1959	Target Neighborhood Hits	704	Shared Neighborhood Hits	679
SwissProt Accessions	Q8R2S1, Q8R1D4	Gene names	Rps6kl1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase-like 1 (EC 2.7.11.1).

VGFR3_MOUSE
NC score	0.693275 (rank : 629)	θ value	6.87365e-08 (rank : 671)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1056	Shared Neighborhood Hits	981
SwissProt Accessions	P35917	Gene names	Flt4, Flt-4
Domain Architecture
Description	Vascular endothelial growth factor receptor 3 precursor (EC 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4).

TXK_HUMAN
NC score	0.693160 (rank : 630)	θ value	4.76016e-09 (rank : 611)
Query Neighborhood Hits	1959	Target Neighborhood Hits	971	Shared Neighborhood Hits	809
SwissProt Accessions	P42681, Q14220	Gene names	TXK
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2).

RPKL1_HUMAN
NC score	0.692880 (rank : 631)	θ value	0.000121331 (rank : 850)
Query Neighborhood Hits	1959	Target Neighborhood Hits	708	Shared Neighborhood Hits	669
SwissProt Accessions	Q9Y6S9, Q69YT9, Q6ZMQ6, Q96NR9, Q9BSU9	Gene names	RPS6KL1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase-like 1 (EC 2.7.11.1).

BMX_HUMAN
NC score	0.690668 (rank : 632)	θ value	3.64472e-09 (rank : 604)
Query Neighborhood Hits	1959	Target Neighborhood Hits	942	Shared Neighborhood Hits	803
SwissProt Accessions	P51813, O60564, Q12871	Gene names	BMX
Domain Architecture
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38).

ABL1_MOUSE
NC score	0.690194 (rank : 633)	θ value	0.000158464 (rank : 852)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1178	Shared Neighborhood Hits	899
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

BMX_MOUSE
NC score	0.689944 (rank : 634)	θ value	9.59137e-10 (rank : 588)
Query Neighborhood Hits	1959	Target Neighborhood Hits	912	Shared Neighborhood Hits	791
SwissProt Accessions	P97504	Gene names	Bmx
Domain Architecture	No domain graphic available
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein homolog).

VGFR3_HUMAN
NC score	0.689658 (rank : 635)	θ value	1.17247e-07 (rank : 680)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1037	Shared Neighborhood Hits	974
SwissProt Accessions	P35916	Gene names	FLT4
Domain Architecture
Description	Vascular endothelial growth factor receptor 3 precursor (EC 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4).

SRMS_MOUSE
NC score	0.689470 (rank : 636)	θ value	3.18553e-13 (rank : 460)
Query Neighborhood Hits	1959	Target Neighborhood Hits	964	Shared Neighborhood Hits	816
SwissProt Accessions	Q62270, Q62360, Q923M5	Gene names	Srms, Srm
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70).

ITK_MOUSE
NC score	0.688945 (rank : 637)	θ value	8.97725e-08 (rank : 674)
Query Neighborhood Hits	1959	Target Neighborhood Hits	985	Shared Neighborhood Hits	815
SwissProt Accessions	Q03526	Gene names	Itk, Emt, Tlk, Tsk
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK).

ABL1_HUMAN
NC score	0.688588 (rank : 638)	θ value	0.000121331 (rank : 844)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1220	Shared Neighborhood Hits	913
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

TIE2_HUMAN
NC score	0.688459 (rank : 639)	θ value	3.77169e-06 (rank : 770)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1192	Shared Neighborhood Hits	888
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

ITK_HUMAN
NC score	0.688406 (rank : 640)	θ value	2.61198e-07 (rank : 698)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1016	Shared Neighborhood Hits	819
SwissProt Accessions	Q08881	Gene names	ITK, EMT, LYK
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT).

TIE2_MOUSE
NC score	0.688196 (rank : 641)	θ value	4.92598e-06 (rank : 773)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1204	Shared Neighborhood Hits	888
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

MATK_MOUSE
NC score	0.687979 (rank : 642)	θ value	1.38499e-08 (rank : 629)
Query Neighborhood Hits	1959	Target Neighborhood Hits	952	Shared Neighborhood Hits	820
SwissProt Accessions	P41242, Q6LE90	Gene names	Matk, Ctk, Ntk
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK).

CSK_HUMAN
NC score	0.687598 (rank : 643)	θ value	2.61198e-07 (rank : 695)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1009	Shared Neighborhood Hits	819
SwissProt Accessions	P41240, Q6FGZ6	Gene names	CSK
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase CYL).

BTK_HUMAN
NC score	0.686988 (rank : 644)	θ value	2.69671e-12 (rank : 497)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1026	Shared Neighborhood Hits	815
SwissProt Accessions	Q06187	Gene names	BTK, AGMX1, ATK, BPK
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK).

BTK_MOUSE
NC score	0.686524 (rank : 645)	θ value	3.52202e-12 (rank : 501)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1017	Shared Neighborhood Hits	814
SwissProt Accessions	P35991, Q61365	Gene names	Btk, Bpk
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB).

TTBK1_HUMAN
NC score	0.685869 (rank : 646)	θ value	0.000461057 (rank : 886)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1058	Shared Neighborhood Hits	832
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

LYN_MOUSE
NC score	0.685491 (rank : 647)	θ value	8.11959e-09 (rank : 621)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1023	Shared Neighborhood Hits	834
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

LRRK2_MOUSE
NC score	0.685358 (rank : 648)	θ value	5.62301e-10 (rank : 578)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1359	Shared Neighborhood Hits	838
SwissProt Accessions	Q5S006, Q8BWG7, Q8BZJ6, Q8CI84, Q8K062	Gene names	Lrrk2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1).

FAK2_MOUSE
NC score	0.685019 (rank : 649)	θ value	7.1131e-05 (rank : 834)
Query Neighborhood Hits	1959	Target Neighborhood Hits	851	Shared Neighborhood Hits	793
SwissProt Accessions	Q9QVP9	Gene names	Ptk2b, Fak2, Pyk2, Raftk
Domain Architecture	No domain graphic available
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

FRK_HUMAN
NC score	0.684667 (rank : 650)	θ value	4.0297e-08 (rank : 657)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1058	Shared Neighborhood Hits	828
SwissProt Accessions	P42685, Q13128	Gene names	FRK
Domain Architecture
Description	Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear tyrosine protein kinase RAK).

LYN_HUMAN
NC score	0.684328 (rank : 651)	θ value	1.80886e-08 (rank : 636)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1022	Shared Neighborhood Hits	834
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

ABL2_HUMAN
NC score	0.683728 (rank : 652)	θ value	5.44631e-05 (rank : 822)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1045	Shared Neighborhood Hits	829
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

MATK_HUMAN
NC score	0.683725 (rank : 653)	θ value	6.87365e-08 (rank : 669)
Query Neighborhood Hits	1959	Target Neighborhood Hits	954	Shared Neighborhood Hits	817
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

SRMS_HUMAN
NC score	0.683063 (rank : 654)	θ value	8.67504e-11 (rank : 556)
Query Neighborhood Hits	1959	Target Neighborhood Hits	946	Shared Neighborhood Hits	814
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).

TXK_MOUSE
NC score	0.681384 (rank : 655)	θ value	4.76016e-09 (rank : 612)
Query Neighborhood Hits	1959	Target Neighborhood Hits	980	Shared Neighborhood Hits	803
SwissProt Accessions	P42682	Gene names	Txk, Rlk
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18) (Resting lymphocyte kinase).

FAK2_HUMAN
NC score	0.680244 (rank : 656)	θ value	0.000121331 (rank : 845)
Query Neighborhood Hits	1959	Target Neighborhood Hits	847	Shared Neighborhood Hits	790
SwissProt Accessions	Q14289, Q13475, Q14290, Q16709	Gene names	PTK2B, FAK2, PYK2, RAFTK
Domain Architecture
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

IRAK1_HUMAN
NC score	0.679838 (rank : 657)	θ value	1.06291 (rank : 1381)
Query Neighborhood Hits	1959	Target Neighborhood Hits	820	Shared Neighborhood Hits	767
SwissProt Accessions	P51617, Q7Z5V4, Q96RL2	Gene names	IRAK1, IRAK
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1).

TNK1_MOUSE
NC score	0.679516 (rank : 658)	θ value	4.45536e-07 (rank : 719)
Query Neighborhood Hits	1959	Target Neighborhood Hits	806	Shared Neighborhood Hits	770
SwissProt Accessions	Q99ML2, Q8CCC4, Q8K0X9, Q91V11	Gene names	Tnk1, Kos1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (Kinase of embryonic stem cells).

CDC7_HUMAN
NC score	0.679128 (rank : 659)	θ value	0.0563607 (rank : 1069)
Query Neighborhood Hits	1959	Target Neighborhood Hits	652	Shared Neighborhood Hits	630
SwissProt Accessions	O00311, O00558	Gene names	CDC7, CDC7L1
Domain Architecture
Description	Cell division cycle 7-related protein kinase (EC 2.7.11.1) (CDC7- related kinase) (HsCdc7) (huCdc7).

UFO_MOUSE
NC score	0.678571 (rank : 660)	θ value	0.00175202 (rank : 938)
Query Neighborhood Hits	1959	Target Neighborhood Hits	988	Shared Neighborhood Hits	896
SwissProt Accessions	Q00993	Gene names	Axl, Ark, Ufo
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (Adhesion-related kinase).

TIE1_MOUSE
NC score	0.677919 (rank : 661)	θ value	9.29e-05 (rank : 843)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1266	Shared Neighborhood Hits	923
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

EPHA5_MOUSE
NC score	0.677823 (rank : 662)	θ value	3.77169e-06 (rank : 767)
Query Neighborhood Hits	1959	Target Neighborhood Hits	950	Shared Neighborhood Hits	860
SwissProt Accessions	Q60629	Gene names	Epha5, Bsk, Cek7, Ehk1
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7).

LCK_MOUSE
NC score	0.676817 (rank : 663)	θ value	3.08544e-08 (rank : 653)
Query Neighborhood Hits	1959	Target Neighborhood Hits	981	Shared Neighborhood Hits	819
SwissProt Accessions	P06240, Q61794, Q61795, Q62320, Q91X65	Gene names	Lck, Lsk-t
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK).

CDC7_MOUSE
NC score	0.676770 (rank : 664)	θ value	0.00228821 (rank : 939)
Query Neighborhood Hits	1959	Target Neighborhood Hits	641	Shared Neighborhood Hits	629
SwissProt Accessions	Q9Z0H0, Q9Z2Y7	Gene names	Cdc7, Cdc7l1
Domain Architecture
Description	Cell division cycle 7-related protein kinase (EC 2.7.11.1) (CDC7- related kinase) (muCdc7).

ROR2_MOUSE
NC score	0.676685 (rank : 665)	θ value	1.38499e-08 (rank : 632)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1000	Shared Neighborhood Hits	930
SwissProt Accessions	Q9Z138	Gene names	Ror2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2) (mROR2).

IRAK1_MOUSE
NC score	0.675147 (rank : 666)	θ value	2.36792 (rank : 1539)
Query Neighborhood Hits	1959	Target Neighborhood Hits	784	Shared Neighborhood Hits	742
SwissProt Accessions	Q62406, Q6Y3Z5, Q6Y3Z6	Gene names	Irak1, Il1rak
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK).

ACK1_HUMAN
NC score	0.675012 (rank : 667)	θ value	7.84624e-12 (rank : 516)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1140	Shared Neighborhood Hits	963
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

EPHB1_HUMAN
NC score	0.674647 (rank : 668)	θ value	7.59969e-07 (rank : 731)
Query Neighborhood Hits	1959	Target Neighborhood Hits	988	Shared Neighborhood Hits	864
SwissProt Accessions	P54762, O43569, O95142, O95143	Gene names	EPHB1, EPHT2, NET
Domain Architecture
Description	Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK).

EPHA7_HUMAN
NC score	0.673908 (rank : 669)	θ value	4.45536e-07 (rank : 712)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1053	Shared Neighborhood Hits	879
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

EPHA7_MOUSE
NC score	0.673625 (rank : 670)	θ value	5.81887e-07 (rank : 722)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1025	Shared Neighborhood Hits	875
SwissProt Accessions	Q61772, Q61505, Q61773, Q61774	Gene names	Epha7, Ebk, Ehk3, Mdk1
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1).

ACK1_MOUSE
NC score	0.673019 (rank : 671)	θ value	7.84624e-12 (rank : 517)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1080	Shared Neighborhood Hits	935
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

MERTK_MOUSE
NC score	0.672949 (rank : 672)	θ value	0.00665767 (rank : 984)
Query Neighborhood Hits	1959	Target Neighborhood Hits	974	Shared Neighborhood Hits	906
SwissProt Accessions	Q60805, Q62194	Gene names	Mertk, Mer
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

TIE1_HUMAN
NC score	0.672828 (rank : 673)	θ value	9.29e-05 (rank : 842)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1241	Shared Neighborhood Hits	909
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

EPHA3_HUMAN
NC score	0.672492 (rank : 674)	θ value	2.88788e-06 (rank : 761)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1005	Shared Neighborhood Hits	885
SwissProt Accessions	P29320, Q9H2V3, Q9H2V4	Gene names	EPHA3, ETK, ETK1, HEK
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4).

LCK_HUMAN
NC score	0.672331 (rank : 675)	θ value	1.80886e-08 (rank : 635)
Query Neighborhood Hits	1959	Target Neighborhood Hits	987	Shared Neighborhood Hits	821
SwissProt Accessions	P06239, P07100, Q12850, Q13152, Q5TDH8, Q5TDH9, Q96DW4, Q9NYT8	Gene names	LCK
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell- specific protein-tyrosine kinase).

TTBK2_HUMAN
NC score	0.672277 (rank : 676)	θ value	0.000461057 (rank : 887)
Query Neighborhood Hits	1959	Target Neighborhood Hits	822	Shared Neighborhood Hits	740
SwissProt Accessions	Q6IQ55, O94932, Q6ZN52, Q8IVV1	Gene names	TTBK2, KIAA0847
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 2 (EC 2.7.11.1).

TNK1_HUMAN
NC score	0.672139 (rank : 677)	θ value	1.87187e-05 (rank : 799)
Query Neighborhood Hits	1959	Target Neighborhood Hits	815	Shared Neighborhood Hits	775
SwissProt Accessions	Q13470, O95364, Q8IYI4	Gene names	TNK1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1).

UFO_HUMAN
NC score	0.671707 (rank : 678)	θ value	0.125558 (rank : 1132)
Query Neighborhood Hits	1959	Target Neighborhood Hits	981	Shared Neighborhood Hits	893
SwissProt Accessions	P30530	Gene names	AXL, UFO
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (AXL oncogene).

BLK_HUMAN
NC score	0.671195 (rank : 679)	θ value	3.77169e-06 (rank : 766)
Query Neighborhood Hits	1959	Target Neighborhood Hits	994	Shared Neighborhood Hits	821
SwissProt Accessions	P51451, Q16291	Gene names	BLK
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

HCK_HUMAN
NC score	0.671105 (rank : 680)	θ value	2.79066e-09 (rank : 602)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1035	Shared Neighborhood Hits	827
SwissProt Accessions	P08631, Q5T7K1, Q5T7K2, Q96CC0, Q9H5Y5, Q9NUA4, Q9UMJ5	Gene names	HCK
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p59-HCK/p60-HCK) (Hemopoietic cell kinase).

BLK_MOUSE
NC score	0.670018 (rank : 681)	θ value	1.99992e-07 (rank : 687)
Query Neighborhood Hits	1959	Target Neighborhood Hits	992	Shared Neighborhood Hits	819
SwissProt Accessions	P16277	Gene names	Blk
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

EPHB4_MOUSE
NC score	0.668855 (rank : 682)	θ value	1.87187e-05 (rank : 797)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1013	Shared Neighborhood Hits	863
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

FYN_HUMAN
NC score	0.668767 (rank : 683)	θ value	7.59969e-07 (rank : 734)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1078	Shared Neighborhood Hits	831
SwissProt Accessions	P06241	Gene names	FYN
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK).

TTBK2_MOUSE
NC score	0.668696 (rank : 684)	θ value	0.00134147 (rank : 930)
Query Neighborhood Hits	1959	Target Neighborhood Hits	811	Shared Neighborhood Hits	725
SwissProt Accessions	Q3UVR3, Q3TSR6, Q3UFW0, Q571D1, Q8BKA4, Q924U8	Gene names	Ttbk2, Kiaa0847, Ttbk1
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 2.

MERTK_HUMAN
NC score	0.667708 (rank : 685)	θ value	0.00134147 (rank : 928)
Query Neighborhood Hits	1959	Target Neighborhood Hits	988	Shared Neighborhood Hits	922
SwissProt Accessions	Q12866, Q9HBB4	Gene names	MERTK, MER
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

RET_HUMAN
NC score	0.666885 (rank : 686)	θ value	8.40245e-06 (rank : 781)
Query Neighborhood Hits	1959	Target Neighborhood Hits	873	Shared Neighborhood Hits	795
SwissProt Accessions	P07949, Q15250	Gene names	RET
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

KS6C1_MOUSE
NC score	0.666797 (rank : 687)	θ value	0.47712 (rank : 1259)
Query Neighborhood Hits	1959	Target Neighborhood Hits	700	Shared Neighborhood Hits	637
SwissProt Accessions	Q8BLK9, Q3UDY3, Q6PDY4, Q8BMQ5, Q8BX49	Gene names	Rps6kc1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase delta-1 (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase).

EPHA5_HUMAN
NC score	0.666492 (rank : 688)	θ value	1.69304e-06 (rank : 753)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1009	Shared Neighborhood Hits	875
SwissProt Accessions	P54756	Gene names	EPHA5, EHK1, HEK7
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein- tyrosine kinase HEK7).

EPHA3_MOUSE
NC score	0.666083 (rank : 689)	θ value	9.29e-05 (rank : 837)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1009	Shared Neighborhood Hits	890
SwissProt Accessions	P29319	Gene names	Epha3, Etk1, Mek4, Tyro4
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (MEK4).

HCK_MOUSE
NC score	0.666056 (rank : 690)	θ value	1.17247e-07 (rank : 677)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1029	Shared Neighborhood Hits	823
SwissProt Accessions	P08103	Gene names	Hck
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK).

KC1A_HUMAN
NC score	0.665438 (rank : 691)	θ value	0.00134147 (rank : 924)
Query Neighborhood Hits	1959	Target Neighborhood Hits	728	Shared Neighborhood Hits	723
SwissProt Accessions	P48729, Q96HD2	Gene names	CSNK1A1
Domain Architecture
Description	Casein kinase I isoform alpha (EC 2.7.11.1) (CKI-alpha) (CK1).

KC1A_MOUSE
NC score	0.665438 (rank : 692)	θ value	0.00134147 (rank : 925)
Query Neighborhood Hits	1959	Target Neighborhood Hits	728	Shared Neighborhood Hits	723
SwissProt Accessions	Q8BK63, Q3UIL0, Q64506, Q80XI2, Q99LY3	Gene names	Csnk1a1
Domain Architecture
Description	Casein kinase I isoform alpha (EC 2.7.11.1) (CKI-alpha) (CK1).

RET_MOUSE
NC score	0.665401 (rank : 693)	θ value	4.1701e-05 (rank : 818)
Query Neighborhood Hits	1959	Target Neighborhood Hits	884	Shared Neighborhood Hits	795
SwissProt Accessions	P35546, Q8BQ34, Q9QXH9	Gene names	Ret
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

ROS_HUMAN
NC score	0.665064 (rank : 694)	θ value	0.00390308 (rank : 964)
Query Neighborhood Hits	1959	Target Neighborhood Hits	907	Shared Neighborhood Hits	825
SwissProt Accessions	P08922, Q15368	Gene names	ROS1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ROS precursor (EC 2.7.10.1) (c- ros-1).

SRC_MOUSE
NC score	0.664777 (rank : 695)	θ value	4.45536e-07 (rank : 717)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1033	Shared Neighborhood Hits	826
SwissProt Accessions	P05480	Gene names	Src
Domain Architecture
Description	Neuronal proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c-Src) (pp60c-src).

EPHB4_HUMAN
NC score	0.664244 (rank : 696)	θ value	1.87187e-05 (rank : 796)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1056	Shared Neighborhood Hits	867
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

FYN_MOUSE
NC score	0.663793 (rank : 697)	θ value	1.29631e-06 (rank : 746)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1073	Shared Neighborhood Hits	833
SwissProt Accessions	P39688	Gene names	Fyn
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn).

SRC_HUMAN
NC score	0.663631 (rank : 698)	θ value	2.61198e-07 (rank : 700)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1058	Shared Neighborhood Hits	823
SwissProt Accessions	P12931, Q86VB9, Q9H5A8	Gene names	SRC, SRC1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c- Src) (pp60c-src).

PGFRA_HUMAN
NC score	0.663313 (rank : 699)	θ value	1.43324e-05 (rank : 791)
Query Neighborhood Hits	1959	Target Neighborhood Hits	980	Shared Neighborhood Hits	928
SwissProt Accessions	P16234, Q96KZ7	Gene names	PDGFRA
Domain Architecture
Description	Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen).

KS6C1_HUMAN
NC score	0.663119 (rank : 700)	θ value	0.365318 (rank : 1219)
Query Neighborhood Hits	1959	Target Neighborhood Hits	682	Shared Neighborhood Hits	636
SwissProt Accessions	Q96S38, Q8TDD3, Q9NSF4, Q9UL66	Gene names	RPS6KC1, RPK118
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase delta-1 (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase) (Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein) (SPHK1-binding protein).

EPHA2_HUMAN
NC score	0.662755 (rank : 701)	θ value	2.21117e-06 (rank : 757)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1021	Shared Neighborhood Hits	871
SwissProt Accessions	P29317	Gene names	EPHA2, ECK
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase).

KC1AL_HUMAN
NC score	0.662683 (rank : 702)	θ value	0.000602161 (rank : 890)
Query Neighborhood Hits	1959	Target Neighborhood Hits	734	Shared Neighborhood Hits	723
SwissProt Accessions	Q8N752	Gene names	CSNK1A1L
Domain Architecture
Description	Casein kinase I isoform alpha-like (EC 2.7.11.1) (CKI-alpha-like) (CK1).

EPHA4_MOUSE
NC score	0.662168 (rank : 703)	θ value	4.45536e-07 (rank : 711)
Query Neighborhood Hits	1959	Target Neighborhood Hits	982	Shared Neighborhood Hits	868
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

EPHA4_HUMAN
NC score	0.661188 (rank : 704)	θ value	4.45536e-07 (rank : 710)
Query Neighborhood Hits	1959	Target Neighborhood Hits	975	Shared Neighborhood Hits	866
SwissProt Accessions	P54764	Gene names	EPHA4, HEK8, SEK
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8).

EPHA8_HUMAN
NC score	0.661064 (rank : 705)	θ value	7.1131e-05 (rank : 833)
Query Neighborhood Hits	1959	Target Neighborhood Hits	956	Shared Neighborhood Hits	868
SwissProt Accessions	P29322, Q9NUA9, Q9P269	Gene names	EPHA8, EEK, KIAA1459
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3).

KC1D_MOUSE
NC score	0.660999 (rank : 706)	θ value	0.000786445 (rank : 904)
Query Neighborhood Hits	1959	Target Neighborhood Hits	737	Shared Neighborhood Hits	723
SwissProt Accessions	Q9DC28, Q3TZK2, Q99KK4	Gene names	Csnk1d
Domain Architecture
Description	Casein kinase I isoform delta (EC 2.7.11.1) (CKI-delta) (CKId).

KC1D_HUMAN
NC score	0.660991 (rank : 707)	θ value	0.000786445 (rank : 903)
Query Neighborhood Hits	1959	Target Neighborhood Hits	737	Shared Neighborhood Hits	723
SwissProt Accessions	P48730, Q96KZ6, Q9BTN5	Gene names	CSNK1D
Domain Architecture
Description	Casein kinase I isoform delta (EC 2.7.11.1) (CKI-delta) (CKId).

PGFRA_MOUSE
NC score	0.660562 (rank : 708)	θ value	1.43324e-05 (rank : 792)
Query Neighborhood Hits	1959	Target Neighborhood Hits	975	Shared Neighborhood Hits	924
SwissProt Accessions	P26618, Q62046	Gene names	Pdgfra
Domain Architecture
Description	Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen).

NTRK1_HUMAN
NC score	0.660095 (rank : 709)	θ value	1.43324e-05 (rank : 790)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1023	Shared Neighborhood Hits	876
SwissProt Accessions	P04629, P08119, Q15655, Q15656, Q5D056, Q5VZS2, Q9UIU7	Gene names	NTRK1, TRK
Domain Architecture
Description	High affinity nerve growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1 transforming tyrosine kinase protein) (p140-TrkA) (Trk-A).

EPHA2_MOUSE
NC score	0.660037 (rank : 710)	θ value	1.29631e-06 (rank : 745)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1020	Shared Neighborhood Hits	862
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

YES_HUMAN
NC score	0.660021 (rank : 711)	θ value	9.92553e-07 (rank : 741)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1059	Shared Neighborhood Hits	821
SwissProt Accessions	P07947	Gene names	YES1, YES
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

YES_MOUSE
NC score	0.659351 (rank : 712)	θ value	1.29631e-06 (rank : 750)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1052	Shared Neighborhood Hits	818
SwissProt Accessions	Q04736	Gene names	Yes1, Yes
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

EPHB2_MOUSE
NC score	0.658694 (rank : 713)	θ value	6.43352e-06 (rank : 775)
Query Neighborhood Hits	1959	Target Neighborhood Hits	982	Shared Neighborhood Hits	859
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

EPHB2_HUMAN
NC score	0.658521 (rank : 714)	θ value	6.43352e-06 (rank : 774)
Query Neighborhood Hits	1959	Target Neighborhood Hits	983	Shared Neighborhood Hits	859
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

EPHA8_MOUSE
NC score	0.658058 (rank : 715)	θ value	2.44474e-05 (rank : 803)
Query Neighborhood Hits	1959	Target Neighborhood Hits	969	Shared Neighborhood Hits	867
SwissProt Accessions	O09127	Gene names	Epha8, Eek
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase).

KC1E_HUMAN
NC score	0.657813 (rank : 716)	θ value	0.000786445 (rank : 905)
Query Neighborhood Hits	1959	Target Neighborhood Hits	732	Shared Neighborhood Hits	721
SwissProt Accessions	P49674	Gene names	CSNK1E
Domain Architecture
Description	Casein kinase I isoform epsilon (EC 2.7.11.1) (CKI-epsilon) (CKIe).

KC1E_MOUSE
NC score	0.657766 (rank : 717)	θ value	0.000786445 (rank : 906)
Query Neighborhood Hits	1959	Target Neighborhood Hits	728	Shared Neighborhood Hits	720
SwissProt Accessions	Q9JMK2, Q8R389	Gene names	Csnk1e
Domain Architecture
Description	Casein kinase I isoform epsilon (EC 2.7.11.1) (CKI-epsilon) (CKIe).

KC1G1_MOUSE
NC score	0.656840 (rank : 718)	θ value	3.41135e-07 (rank : 706)
Query Neighborhood Hits	1959	Target Neighborhood Hits	713	Shared Neighborhood Hits	703
SwissProt Accessions	Q8BTH8	Gene names	Csnk1g1
Domain Architecture
Description	Casein kinase I isoform gamma-1 (EC 2.7.11.1) (CKI-gamma 1).

EPHB3_HUMAN
NC score	0.656709 (rank : 719)	θ value	5.26297e-08 (rank : 661)
Query Neighborhood Hits	1959	Target Neighborhood Hits	996	Shared Neighborhood Hits	876
SwissProt Accessions	P54753, Q7Z740	Gene names	EPHB3, ETK2, HEK2
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2).

ERBB4_HUMAN
NC score	0.656596 (rank : 720)	θ value	0.00102713 (rank : 915)
Query Neighborhood Hits	1959	Target Neighborhood Hits	910	Shared Neighborhood Hits	797
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

STYK1_HUMAN
NC score	0.656401 (rank : 721)	θ value	0.00509761 (rank : 977)
Query Neighborhood Hits	1959	Target Neighborhood Hits	786	Shared Neighborhood Hits	764
SwissProt Accessions	Q6J9G0, Q9BXY2, Q9NSH1	Gene names	STYK1, NOK
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (Protein PK-unique).

EPHB3_MOUSE
NC score	0.655547 (rank : 722)	θ value	5.26297e-08 (rank : 662)
Query Neighborhood Hits	1959	Target Neighborhood Hits	996	Shared Neighborhood Hits	873
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

EGFR_MOUSE
NC score	0.655494 (rank : 723)	θ value	0.000786445 (rank : 899)
Query Neighborhood Hits	1959	Target Neighborhood Hits	927	Shared Neighborhood Hits	805
SwissProt Accessions	Q01279	Gene names	Egfr
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1).

FGR_HUMAN
NC score	0.655190 (rank : 724)	θ value	2.61198e-07 (rank : 697)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1067	Shared Neighborhood Hits	829
SwissProt Accessions	P09769, Q9UIQ3	Gene names	FGR, SRC2
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

EGFR_HUMAN
NC score	0.655090 (rank : 725)	θ value	0.000786445 (rank : 898)
Query Neighborhood Hits	1959	Target Neighborhood Hits	939	Shared Neighborhood Hits	799
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

KC1G1_HUMAN
NC score	0.654840 (rank : 726)	θ value	3.41135e-07 (rank : 705)
Query Neighborhood Hits	1959	Target Neighborhood Hits	708	Shared Neighborhood Hits	700
SwissProt Accessions	Q9HCP0, Q96AE9, Q9HCP1	Gene names	CSNK1G1
Domain Architecture
Description	Casein kinase I isoform gamma-1 (EC 2.7.11.1) (CKI-gamma 1).

PGFRB_MOUSE
NC score	0.653334 (rank : 727)	θ value	4.1701e-05 (rank : 817)
Query Neighborhood Hits	1959	Target Neighborhood Hits	960	Shared Neighborhood Hits	913
SwissProt Accessions	P05622	Gene names	Pdgfrb, Pdgfr
Domain Architecture
Description	Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen).

RON_HUMAN
NC score	0.652470 (rank : 728)	θ value	5.81887e-07 (rank : 725)
Query Neighborhood Hits	1959	Target Neighborhood Hits	842	Shared Neighborhood Hits	794
SwissProt Accessions	Q04912	Gene names	MST1R, RON
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (CDw136 antigen) [Contains: Macrophage- stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

FGR_MOUSE
NC score	0.652278 (rank : 729)	θ value	3.41135e-07 (rank : 704)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1069	Shared Neighborhood Hits	826
SwissProt Accessions	P14234, Q61404	Gene names	Fgr
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

KC1G3_HUMAN
NC score	0.651434 (rank : 730)	θ value	1.29631e-06 (rank : 747)
Query Neighborhood Hits	1959	Target Neighborhood Hits	711	Shared Neighborhood Hits	705
SwissProt Accessions	Q9Y6M4, Q86WZ7, Q9Y6M3	Gene names	CSNK1G3
Domain Architecture
Description	Casein kinase I isoform gamma-3 (EC 2.7.11.1) (CKI-gamma 3).

TNI3K_MOUSE
NC score	0.649571 (rank : 731)	θ value	0.00390308 (rank : 972)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1079	Shared Neighborhood Hits	788
SwissProt Accessions	Q5GIG6, Q5GIG5	Gene names	Tnni3k, Cark
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

PGFRB_HUMAN
NC score	0.649523 (rank : 732)	θ value	1.43324e-05 (rank : 793)
Query Neighborhood Hits	1959	Target Neighborhood Hits	962	Shared Neighborhood Hits	919
SwissProt Accessions	P09619, Q8N5L4	Gene names	PDGFRB
Domain Architecture
Description	Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen).

EPHA1_HUMAN
NC score	0.647927 (rank : 733)	θ value	4.45536e-07 (rank : 709)
Query Neighborhood Hits	1959	Target Neighborhood Hits	997	Shared Neighborhood Hits	843
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

ERBB2_MOUSE
NC score	0.647751 (rank : 734)	θ value	4.1701e-05 (rank : 814)
Query Neighborhood Hits	1959	Target Neighborhood Hits	918	Shared Neighborhood Hits	815
SwissProt Accessions	P70424, Q61525, Q6ZPE0	Gene names	Erbb2, Kiaa3023, Neu
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene).

ERBB2_HUMAN
NC score	0.646232 (rank : 735)	θ value	5.44631e-05 (rank : 824)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1073	Shared Neighborhood Hits	876
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

MET_MOUSE
NC score	0.645478 (rank : 736)	θ value	3.19293e-05 (rank : 810)
Query Neighborhood Hits	1959	Target Neighborhood Hits	844	Shared Neighborhood Hits	785
SwissProt Accessions	P16056, Q62125	Gene names	Met
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

AATK_HUMAN
NC score	0.644918 (rank : 737)	θ value	0.000158464 (rank : 851)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1243	Shared Neighborhood Hits	950
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

INSR_HUMAN
NC score	0.644870 (rank : 738)	θ value	1.87187e-05 (rank : 798)
Query Neighborhood Hits	1959	Target Neighborhood Hits	963	Shared Neighborhood Hits	829
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

INSR_MOUSE
NC score	0.644590 (rank : 739)	θ value	8.40245e-06 (rank : 780)
Query Neighborhood Hits	1959	Target Neighborhood Hits	968	Shared Neighborhood Hits	825
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

KIT_HUMAN
NC score	0.644559 (rank : 740)	θ value	0.000602161 (rank : 891)
Query Neighborhood Hits	1959	Target Neighborhood Hits	953	Shared Neighborhood Hits	907
SwissProt Accessions	P10721, Q9UM99	Gene names	KIT
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

KIT_MOUSE
NC score	0.644275 (rank : 741)	θ value	0.00298849 (rank : 954)
Query Neighborhood Hits	1959	Target Neighborhood Hits	949	Shared Neighborhood Hits	912
SwissProt Accessions	P05532, Q61415, Q61416, Q61417, Q6LEE9	Gene names	Kit, Sl
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

AVR2A_MOUSE
NC score	0.643413 (rank : 742)	θ value	0.000270298 (rank : 869)
Query Neighborhood Hits	1959	Target Neighborhood Hits	767	Shared Neighborhood Hits	751
SwissProt Accessions	P27038	Gene names	Acvr2a, Acvr2
Domain Architecture
Description	Activin receptor type 2A precursor (EC 2.7.11.30) (Activin receptor type IIA) (ACTR-IIA).

AVR2A_HUMAN
NC score	0.643399 (rank : 743)	θ value	0.000270298 (rank : 868)
Query Neighborhood Hits	1959	Target Neighborhood Hits	767	Shared Neighborhood Hits	751
SwissProt Accessions	P27037, Q53TH4, Q6NWV2, Q92474	Gene names	ACVR2A, ACVR2
Domain Architecture
Description	Activin receptor type 2A precursor (EC 2.7.11.30) (Activin receptor type IIA) (ACTR-IIA) (ACTRIIA).

MET_HUMAN
NC score	0.643298 (rank : 744)	θ value	5.44631e-05 (rank : 829)
Query Neighborhood Hits	1959	Target Neighborhood Hits	831	Shared Neighborhood Hits	784
SwissProt Accessions	P08581, O60366, Q12875, Q9UDX7, Q9UPL8	Gene names	MET
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

TNI3K_HUMAN
NC score	0.643286 (rank : 745)	θ value	0.00175202 (rank : 937)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1084	Shared Neighborhood Hits	793
SwissProt Accessions	Q59H18, Q49AR1, Q6MZS9, Q9Y2V6	Gene names	TNNI3K, CARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

STYK1_MOUSE
NC score	0.642407 (rank : 746)	θ value	1.29631e-06 (rank : 749)
Query Neighborhood Hits	1959	Target Neighborhood Hits	779	Shared Neighborhood Hits	757
SwissProt Accessions	Q6J9G1, Q8BZH6, Q8BZT1	Gene names	Styk1, Nok
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (mNOK).

RON_MOUSE
NC score	0.641409 (rank : 747)	θ value	3.77169e-06 (rank : 769)
Query Neighborhood Hits	1959	Target Neighborhood Hits	836	Shared Neighborhood Hits	785
SwissProt Accessions	Q62190, Q62555	Gene names	Mst1r, Ron, Stk
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

DDR2_MOUSE
NC score	0.641182 (rank : 748)	θ value	1.43324e-05 (rank : 788)
Query Neighborhood Hits	1959	Target Neighborhood Hits	813	Shared Neighborhood Hits	767
SwissProt Accessions	Q62371	Gene names	Ddr2, Ntrkr3, Tkt, Tyro10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

EPHA1_MOUSE
NC score	0.639627 (rank : 749)	θ value	1.69304e-06 (rank : 752)
Query Neighborhood Hits	1959	Target Neighborhood Hits	958	Shared Neighborhood Hits	837
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

DDR2_HUMAN
NC score	0.635407 (rank : 750)	θ value	2.88788e-06 (rank : 760)
Query Neighborhood Hits	1959	Target Neighborhood Hits	818	Shared Neighborhood Hits	765
SwissProt Accessions	Q16832	Gene names	DDR2, NTRKR3, TKT, TYRO10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

CSF1R_MOUSE
NC score	0.633504 (rank : 751)	θ value	5.44631e-05 (rank : 823)
Query Neighborhood Hits	1959	Target Neighborhood Hits	983	Shared Neighborhood Hits	933
SwissProt Accessions	P09581, Q3U3P1, Q9DBH9	Gene names	Csf1r, Csfmr, Fms
Domain Architecture
Description	Macrophage colony-stimulating factor 1 receptor precursor (EC 2.7.10.1) (CSF-1-R) (Fms proto-oncogene) (c-fms) (CD115 antigen).

AATK_MOUSE
NC score	0.632070 (rank : 752)	θ value	3.19293e-05 (rank : 807)
Query Neighborhood Hits	1959	Target Neighborhood Hits	942	Shared Neighborhood Hits	813
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

TGFR2_MOUSE
NC score	0.631444 (rank : 753)	θ value	0.0330416 (rank : 1051)
Query Neighborhood Hits	1959	Target Neighborhood Hits	748	Shared Neighborhood Hits	729
SwissProt Accessions	Q62312, Q63947	Gene names	Tgfbr2
Domain Architecture
Description	TGF-beta receptor type-2 precursor (EC 2.7.11.30) (TGF-beta receptor type II) (TGFR-2) (TGF-beta type II receptor).

TGFR2_HUMAN
NC score	0.631277 (rank : 754)	θ value	0.0330416 (rank : 1050)
Query Neighborhood Hits	1959	Target Neighborhood Hits	748	Shared Neighborhood Hits	728
SwissProt Accessions	P37173, Q15580, Q6DKT6, Q99474	Gene names	TGFBR2
Domain Architecture
Description	TGF-beta receptor type-2 precursor (EC 2.7.11.30) (TGF-beta receptor type II) (TGFR-2) (TGF-beta type II receptor).

INSRR_MOUSE
NC score	0.629775 (rank : 755)	θ value	0.00134147 (rank : 920)
Query Neighborhood Hits	1959	Target Neighborhood Hits	961	Shared Neighborhood Hits	807
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

AVR2B_MOUSE
NC score	0.629644 (rank : 756)	θ value	1.09739e-05 (rank : 784)
Query Neighborhood Hits	1959	Target Neighborhood Hits	749	Shared Neighborhood Hits	728
SwissProt Accessions	P27040	Gene names	Acvr2b
Domain Architecture
Description	Activin receptor type 2B precursor (EC 2.7.11.30) (Activin receptor type IIB) (ACTR-IIB).

AVR2B_HUMAN
NC score	0.629437 (rank : 757)	θ value	1.09739e-05 (rank : 783)
Query Neighborhood Hits	1959	Target Neighborhood Hits	748	Shared Neighborhood Hits	728
SwissProt Accessions	Q13705, Q4VAV0	Gene names	ACVR2B
Domain Architecture
Description	Activin receptor type 2B precursor (EC 2.7.11.30) (Activin receptor type IIB) (ACTR-IIB).

IGF1R_MOUSE
NC score	0.627372 (rank : 758)	θ value	0.000158464 (rank : 855)
Query Neighborhood Hits	1959	Target Neighborhood Hits	973	Shared Neighborhood Hits	816
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

INSRR_HUMAN
NC score	0.626913 (rank : 759)	θ value	0.000786445 (rank : 902)
Query Neighborhood Hits	1959	Target Neighborhood Hits	950	Shared Neighborhood Hits	808
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

KC1G2_MOUSE
NC score	0.626672 (rank : 760)	θ value	6.43352e-06 (rank : 776)
Query Neighborhood Hits	1959	Target Neighborhood Hits	695	Shared Neighborhood Hits	686
SwissProt Accessions	Q8BVP5	Gene names	Csnk1g2
Domain Architecture	No domain graphic available
Description	Casein kinase I isoform gamma-2 (EC 2.7.11.1) (CKI-gamma 2).

KC1G2_HUMAN
NC score	0.625601 (rank : 761)	θ value	2.88788e-06 (rank : 762)
Query Neighborhood Hits	1959	Target Neighborhood Hits	693	Shared Neighborhood Hits	686
SwissProt Accessions	P78368, O00704, Q8WUB1	Gene names	CSNK1G2
Domain Architecture
Description	Casein kinase I isoform gamma-2 (EC 2.7.11.1) (CKI-gamma 2).

IGF1R_HUMAN
NC score	0.625330 (rank : 762)	θ value	0.000121331 (rank : 847)
Query Neighborhood Hits	1959	Target Neighborhood Hits	977	Shared Neighborhood Hits	818
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

IRAK2_HUMAN
NC score	0.624587 (rank : 763)	θ value	5.27518 (rank : 1749)
Query Neighborhood Hits	1959	Target Neighborhood Hits	714	Shared Neighborhood Hits	689
SwissProt Accessions	O43187	Gene names	IRAK2
Domain Architecture
Description	Interleukin-1 receptor-associated kinase-like 2 (IRAK-2).

ACVR1_MOUSE
NC score	0.622615 (rank : 764)	θ value	0.0563607 (rank : 1066)
Query Neighborhood Hits	1959	Target Neighborhood Hits	768	Shared Neighborhood Hits	748
SwissProt Accessions	P37172, Q3UDH5, Q91VF1	Gene names	Acvr1, Acvrlk2, Tgfb1
Domain Architecture
Description	Activin receptor type-1 precursor (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) (Serine/threonine-protein kinase receptor R1) (SKR1) (TGF-B superfamily receptor type I) (TSR-I) (TSK-7L).

ERBB3_MOUSE
NC score	0.621587 (rank : 765)	θ value	9.29e-05 (rank : 838)
Query Neighborhood Hits	1959	Target Neighborhood Hits	898	Shared Neighborhood Hits	770
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

MLKL_MOUSE
NC score	0.620402 (rank : 766)	θ value	2.36792 (rank : 1547)
Query Neighborhood Hits	1959	Target Neighborhood Hits	707	Shared Neighborhood Hits	681
SwissProt Accessions	Q9D2Y4, Q8CIJ5	Gene names	Mlkl
Domain Architecture	No domain graphic available
Description	Mixed lineage kinase domain-like protein.

ERBB3_HUMAN
NC score	0.617812 (rank : 767)	θ value	0.00020696 (rank : 862)
Query Neighborhood Hits	1959	Target Neighborhood Hits	918	Shared Neighborhood Hits	768
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

CSF1R_HUMAN
NC score	0.616946 (rank : 768)	θ value	0.000158464 (rank : 853)
Query Neighborhood Hits	1959	Target Neighborhood Hits	943	Shared Neighborhood Hits	901
SwissProt Accessions	P07333, Q6LDW5, Q6LDY4	Gene names	CSF1R, FMS
Domain Architecture
Description	Macrophage colony-stimulating factor 1 receptor precursor (EC 2.7.10.1) (CSF-1-R) (Fms proto-oncogene) (c-fms) (CD115 antigen).

SCYL2_HUMAN
NC score	0.616772 (rank : 769)	θ value	2.44474e-05 (rank : 805)
Query Neighborhood Hits	1959	Target Neighborhood Hits	632	Shared Neighborhood Hits	566
SwissProt Accessions	Q6P3W7, Q96EF4, Q96ST4, Q9H7V5, Q9NVH3, Q9P2I7	Gene names	SCYL2, CVAK104, KIAA1360
Domain Architecture	No domain graphic available
Description	SCY1-like protein 2 (Coated vesicle-associated kinase of 104 kDa).

ACVR1_HUMAN
NC score	0.616553 (rank : 770)	θ value	0.0736092 (rank : 1086)
Query Neighborhood Hits	1959	Target Neighborhood Hits	760	Shared Neighborhood Hits	742
SwissProt Accessions	Q04771	Gene names	ACVR1, ACVRLK2
Domain Architecture
Description	Activin receptor type-1 precursor (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) (Serine/threonine-protein kinase receptor R1) (SKR1) (Activin receptor-like kinase 2) (ALK-2) (TGF-B superfamily receptor type I) (TSR-I).

FLT3_MOUSE
NC score	0.612483 (rank : 771)	θ value	0.000270298 (rank : 872)
Query Neighborhood Hits	1959	Target Neighborhood Hits	847	Shared Neighborhood Hits	826
SwissProt Accessions	Q00342	Gene names	Flt3, Flk-2, Flt-3
Domain Architecture
Description	FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor flk-2) (Fetal liver kinase 2) (Tyrosine-protein kinase FLT3) (CD135 antigen).

DDR1_MOUSE
NC score	0.611934 (rank : 772)	θ value	0.00298849 (rank : 951)
Query Neighborhood Hits	1959	Target Neighborhood Hits	818	Shared Neighborhood Hits	761
SwissProt Accessions	Q03146	Gene names	Ddr1, Cak, Eddr1, Mpk6
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (Protein-tyrosine kinase MPK-6) (CD167a antigen).

DDR1_HUMAN
NC score	0.609797 (rank : 773)	θ value	0.00175202 (rank : 932)
Query Neighborhood Hits	1959	Target Neighborhood Hits	819	Shared Neighborhood Hits	762
SwissProt Accessions	Q08345, Q14196, Q16562, Q5ST12, Q9UD37	Gene names	DDR1, CAK, EDDR1, RTK6, TRKE
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (TRK E) (Protein-tyrosine kinase RTK 6) (HGK2) (CD167a antigen).

BMR1A_HUMAN
NC score	0.609294 (rank : 774)	θ value	0.0431538 (rank : 1054)
Query Neighborhood Hits	1959	Target Neighborhood Hits	759	Shared Neighborhood Hits	736
SwissProt Accessions	P36894, Q8NEN8	Gene names	BMPR1A, ACVRLK3, ALK3
Domain Architecture
Description	Bone morphogenetic protein receptor type IA precursor (EC 2.7.11.30) (Serine/threonine-protein kinase receptor R5) (SKR5) (Activin receptor-like kinase 3) (ALK-3) (CD292 antigen).

EPHA6_MOUSE
NC score	0.609032 (rank : 775)	θ value	0.000786445 (rank : 901)
Query Neighborhood Hits	1959	Target Neighborhood Hits	946	Shared Neighborhood Hits	839
SwissProt Accessions	Q62413, Q8CCN2	Gene names	Epha6, Ehk-2, Ehk2
Domain Architecture
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

BMR1A_MOUSE
NC score	0.608372 (rank : 776)	θ value	0.0431538 (rank : 1055)
Query Neighborhood Hits	1959	Target Neighborhood Hits	758	Shared Neighborhood Hits	736
SwissProt Accessions	P36895	Gene names	Bmpr1a, Acvrlk3, Bmpr
Domain Architecture
Description	Bone morphogenetic protein receptor type IA precursor (EC 2.7.11.30) (Serine/threonine-protein kinase receptor R5) (SKR5) (Activin receptor-like kinase 3) (ALK-3) (BMP-2/BMP-4 receptor).

FLT3_HUMAN
NC score	0.607656 (rank : 777)	θ value	0.000461057 (rank : 881)
Query Neighborhood Hits	1959	Target Neighborhood Hits	843	Shared Neighborhood Hits	817
SwissProt Accessions	P36888, Q13414	Gene names	FLT3, STK1
Domain Architecture
Description	FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor FLT3) (Stem cell tyrosine kinase 1) (STK-1) (CD135 antigen).

EPHA6_HUMAN
NC score	0.607415 (rank : 778)	θ value	0.000786445 (rank : 900)
Query Neighborhood Hits	1959	Target Neighborhood Hits	959	Shared Neighborhood Hits	845
SwissProt Accessions	Q9UF33	Gene names	EPHA6, EHK2
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

ALK_HUMAN
NC score	0.606924 (rank : 779)	θ value	2.44474e-05 (rank : 802)
Query Neighborhood Hits	1959	Target Neighborhood Hits	795	Shared Neighborhood Hits	732
SwissProt Accessions	Q9UM73, Q9Y4K6	Gene names	ALK
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

ALK_MOUSE
NC score	0.604993 (rank : 780)	θ value	8.40245e-06 (rank : 778)
Query Neighborhood Hits	1959	Target Neighborhood Hits	811	Shared Neighborhood Hits	739
SwissProt Accessions	P97793	Gene names	Alk
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

LTK_MOUSE
NC score	0.604208 (rank : 781)	θ value	5.44631e-05 (rank : 828)
Query Neighborhood Hits	1959	Target Neighborhood Hits	770	Shared Neighborhood Hits	736
SwissProt Accessions	P08923	Gene names	Ltk
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1).

TGFR1_HUMAN
NC score	0.599481 (rank : 782)	θ value	0.0252991 (rank : 1033)
Query Neighborhood Hits	1959	Target Neighborhood Hits	755	Shared Neighborhood Hits	735
SwissProt Accessions	P36897	Gene names	TGFBR1
Domain Architecture
Description	TGF-beta receptor type-1 precursor (EC 2.7.11.30) (TGF-beta receptor type I) (TGFR-1) (TGF-beta type I receptor) (Serine/threonine-protein kinase receptor R4) (SKR4) (Activin receptor-like kinase 5) (ALK-5).

TGFR1_MOUSE
NC score	0.599139 (rank : 783)	θ value	0.0252991 (rank : 1034)
Query Neighborhood Hits	1959	Target Neighborhood Hits	753	Shared Neighborhood Hits	735
SwissProt Accessions	Q64729	Gene names	Tgfbr1
Domain Architecture
Description	TGF-beta receptor type-1 precursor (EC 2.7.11.30) (TGF-beta receptor type I) (TGFR-1) (TGF-beta type I receptor) (ESK2).

LTK_HUMAN
NC score	0.598945 (rank : 784)	θ value	1.09739e-05 (rank : 785)
Query Neighborhood Hits	1959	Target Neighborhood Hits	774	Shared Neighborhood Hits	740
SwissProt Accessions	P29376	Gene names	LTK, TYK1
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1) (Protein tyrosine kinase 1).

SCYL2_MOUSE
NC score	0.597534 (rank : 785)	θ value	3.19293e-05 (rank : 813)
Query Neighborhood Hits	1959	Target Neighborhood Hits	603	Shared Neighborhood Hits	542
SwissProt Accessions	Q8CFE4, Q3UT57, Q3UWU9, Q8K0M4	Gene names	Scyl2, Cvak104, D10Ertd802e
Domain Architecture	No domain graphic available
Description	SCY1-like protein 2 (Coated vesicle-associated kinase of 104 kDa).

BMR1B_MOUSE
NC score	0.594481 (rank : 786)	θ value	θ > 10 (rank : 1970)
Query Neighborhood Hits	1959	Target Neighborhood Hits	758	Shared Neighborhood Hits	737
SwissProt Accessions	P36898, Q3TRF2	Gene names	Bmpr1b, Acvrlk6
Domain Architecture
Description	Bone morphogenetic protein receptor type IB precursor (EC 2.7.11.30) (Serine/threonine-protein kinase receptor R6) (SKR6) (Activin receptor-like kinase 6) (ALK-6).

ACV1B_MOUSE
NC score	0.594161 (rank : 787)	θ value	θ > 10 (rank : 1961)
Query Neighborhood Hits	1959	Target Neighborhood Hits	753	Shared Neighborhood Hits	735
SwissProt Accessions	Q61271	Gene names	Acvr1b
Domain Architecture
Description	Activin receptor type 1B precursor (EC 2.7.11.30) (ACTR-IB) (Serine/threonine-protein kinase receptor R2) (SKR2).

ACV1B_HUMAN
NC score	0.593876 (rank : 788)	θ value	θ > 10 (rank : 1960)
Query Neighborhood Hits	1959	Target Neighborhood Hits	753	Shared Neighborhood Hits	735
SwissProt Accessions	P36896, Q15479, Q15480, Q15481, Q15482	Gene names	ACVR1B, ACVRLK4
Domain Architecture
Description	Activin receptor type 1B precursor (EC 2.7.11.30) (ACTR-IB) (Serine/threonine-protein kinase receptor R2) (SKR2) (Activin receptor-like kinase 4) (ALK-4).

ANKK1_MOUSE
NC score	0.593376 (rank : 789)	θ value	0.000786445 (rank : 897)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1072	Shared Neighborhood Hits	790
SwissProt Accessions	Q8BZ25	Gene names	Ankk1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1).

BMR1B_HUMAN
NC score	0.593118 (rank : 790)	θ value	θ > 10 (rank : 1969)
Query Neighborhood Hits	1959	Target Neighborhood Hits	760	Shared Neighborhood Hits	736
SwissProt Accessions	O00238, P78366	Gene names	BMPR1B
Domain Architecture
Description	Bone morphogenetic protein receptor type IB precursor (EC 2.7.11.30) (CDw293 antigen).

IRAK3_MOUSE
NC score	0.587285 (rank : 791)	θ value	0.279714 (rank : 1182)
Query Neighborhood Hits	1959	Target Neighborhood Hits	628	Shared Neighborhood Hits	597
SwissProt Accessions	Q8K4B2, Q8C7U8, Q8CE40, Q8K1S8	Gene names	Irak3
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1) (IRAK-3) (IL- 1 receptor-associated kinase M) (IRAK-M).

BMPR2_HUMAN
NC score	0.585223 (rank : 792)	θ value	0.279714 (rank : 1177)
Query Neighborhood Hits	1959	Target Neighborhood Hits	736	Shared Neighborhood Hits	697
SwissProt Accessions	Q13873, Q16569	Gene names	BMPR2, PPH1
Domain Architecture
Description	Bone morphogenetic protein receptor type-2 precursor (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II).

BMPR2_MOUSE
NC score	0.584528 (rank : 793)	θ value	0.0961366 (rank : 1103)
Query Neighborhood Hits	1959	Target Neighborhood Hits	738	Shared Neighborhood Hits	697
SwissProt Accessions	O35607	Gene names	Bmpr2
Domain Architecture
Description	Bone morphogenetic protein receptor type-2 precursor (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II) (BRK-3).

IRAK3_HUMAN
NC score	0.583713 (rank : 794)	θ value	1.06291 (rank : 1382)
Query Neighborhood Hits	1959	Target Neighborhood Hits	644	Shared Neighborhood Hits	620
SwissProt Accessions	Q9Y616	Gene names	IRAK3
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1) (IRAK-3) (IL- 1 receptor-associated kinase M) (IRAK-M).

TOPK_MOUSE
NC score	0.582944 (rank : 795)	θ value	θ > 10 (rank : 2108)
Query Neighborhood Hits	1959	Target Neighborhood Hits	618	Shared Neighborhood Hits	595
SwissProt Accessions	Q9JJ78, Q922V2, Q9D184	Gene names	Pbk, Topk
Domain Architecture	No domain graphic available
Description	T-lymphokine-activated killer cell-originated protein kinase (EC 2.7.12.2) (T-LAK cell-originated protein kinase) (PDZ-binding kinase).

RIPK4_HUMAN
NC score	0.582583 (rank : 796)	θ value	0.00390308 (rank : 963)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1094	Shared Neighborhood Hits	796
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

ANKK1_HUMAN
NC score	0.582202 (rank : 797)	θ value	0.000602161 (rank : 888)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1075	Shared Neighborhood Hits	785
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

TOPK_HUMAN
NC score	0.577739 (rank : 798)	θ value	θ > 10 (rank : 2107)
Query Neighborhood Hits	1959	Target Neighborhood Hits	605	Shared Neighborhood Hits	583
SwissProt Accessions	Q96KB5, Q9NPD9, Q9NYL7, Q9NZK6	Gene names	PBK, TOPK
Domain Architecture	No domain graphic available
Description	T-lymphokine-activated killer cell-originated protein kinase (EC 2.7.12.2) (T-LAK cell-originated protein kinase) (PDZ-binding kinase) (Spermatogenesis-related protein kinase) (SPK) (MAPKK-like protein kinase) (Nori-3).

BUB1_MOUSE
NC score	0.576581 (rank : 799)	θ value	0.000270298 (rank : 870)
Query Neighborhood Hits	1959	Target Neighborhood Hits	583	Shared Neighborhood Hits	538
SwissProt Accessions	O08901, O09007	Gene names	Bub1
Domain Architecture
Description	Mitotic checkpoint serine/threonine-protein kinase BUB1 (EC 2.7.11.1) (MBUB1) (BUB1A).

ACVL1_MOUSE
NC score	0.574788 (rank : 800)	θ value	1.38821 (rank : 1420)
Query Neighborhood Hits	1959	Target Neighborhood Hits	739	Shared Neighborhood Hits	724
SwissProt Accessions	Q61288, Q61289	Gene names	Acvrl1, Acvrlk1, Alk-1
Domain Architecture
Description	Serine/threonine-protein kinase receptor R3 precursor (EC 2.7.11.30) (SKR3) (Activin receptor-like kinase 1) (ALK-1) (TGF-B superfamily receptor type I) (TSR-I).

EPHB6_MOUSE
NC score	0.566189 (rank : 801)	θ value	0.365318 (rank : 1209)
Query Neighborhood Hits	1959	Target Neighborhood Hits	906	Shared Neighborhood Hits	778
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

ACVL1_HUMAN
NC score	0.554581 (rank : 802)	θ value	θ > 10 (rank : 1962)
Query Neighborhood Hits	1959	Target Neighborhood Hits	716	Shared Neighborhood Hits	699
SwissProt Accessions	P37023	Gene names	ACVRL1, ACVRLK1, ALK1
Domain Architecture
Description	Serine/threonine-protein kinase receptor R3 precursor (EC 2.7.11.30) (SKR3) (Activin receptor-like kinase 1) (ALK-1) (TGF-B superfamily receptor type I) (TSR-I).

EPHB6_HUMAN
NC score	0.553618 (rank : 803)	θ value	0.0148317 (rank : 1009)
Query Neighborhood Hits	1959	Target Neighborhood Hits	912	Shared Neighborhood Hits	754
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

EPHAA_HUMAN
NC score	0.553415 (rank : 804)	θ value	0.00390308 (rank : 961)
Query Neighborhood Hits	1959	Target Neighborhood Hits	960	Shared Neighborhood Hits	788
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

RYK_MOUSE
NC score	0.551917 (rank : 805)	θ value	8.11959e-09 (rank : 622)
Query Neighborhood Hits	1959	Target Neighborhood Hits	715	Shared Neighborhood Hits	692
SwissProt Accessions	Q01887, Q61890	Gene names	Ryk, Mrk
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1) (Kinase VIK) (NYK- R) (Met-related kinase).

ACV1C_MOUSE
NC score	0.540637 (rank : 806)	θ value	0.62314 (rank : 1282)
Query Neighborhood Hits	1959	Target Neighborhood Hits	715	Shared Neighborhood Hits	689
SwissProt Accessions	Q8K348	Gene names	Acvr1c, Alk7
Domain Architecture	No domain graphic available
Description	Activin receptor type 1C precursor (EC 2.7.11.30) (ACTR-IC) (Activin receptor-like kinase 7) (ALK-7).

SRPK1_MOUSE
NC score	0.539174 (rank : 807)	θ value	0.00390308 (rank : 968)
Query Neighborhood Hits	1959	Target Neighborhood Hits	639	Shared Neighborhood Hits	573
SwissProt Accessions	O70551, O70193, Q99JT3	Gene names	Srpk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SRPK1 (EC 2.7.11.1) (Serine/arginine- rich protein-specific kinase 1) (SR-protein-specific kinase 1) (SFRS protein kinase 1).

SRPK2_HUMAN
NC score	0.538407 (rank : 808)	θ value	0.000786445 (rank : 912)
Query Neighborhood Hits	1959	Target Neighborhood Hits	664	Shared Neighborhood Hits	573
SwissProt Accessions	P78362, O75220, O75221, Q6NUL0, Q6V1X2, Q8IYQ3	Gene names	SRPK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SRPK2 (EC 2.7.11.1) (Serine/arginine- rich protein-specific kinase 2) (SR-protein-specific kinase 2) (SFRS protein kinase 2).

RYK_HUMAN
NC score	0.537799 (rank : 809)	θ value	5.26297e-08 (rank : 663)
Query Neighborhood Hits	1959	Target Neighborhood Hits	701	Shared Neighborhood Hits	681
SwissProt Accessions	P34925, Q04696	Gene names	RYK, JTK5A
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1).

SRPK1_HUMAN
NC score	0.537527 (rank : 810)	θ value	0.00390308 (rank : 967)
Query Neighborhood Hits	1959	Target Neighborhood Hits	706	Shared Neighborhood Hits	593
SwissProt Accessions	Q96SB4, Q12890, Q5R364, Q5R365, Q8IY12	Gene names	SRPK1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SRPK1 (EC 2.7.11.1) (Serine/arginine- rich protein-specific kinase 1) (SR-protein-specific kinase 1) (SFRS protein kinase 1).

ACV1C_HUMAN
NC score	0.536291 (rank : 811)	θ value	1.06291 (rank : 1355)
Query Neighborhood Hits	1959	Target Neighborhood Hits	709	Shared Neighborhood Hits	684
SwissProt Accessions	Q8NER5, Q4ZFZ8, Q86UL1, Q86UL2, Q8TBG2	Gene names	ACVR1C, ALK7
Domain Architecture	No domain graphic available
Description	Activin receptor type 1C precursor (EC 2.7.11.30) (ACTR-IC) (Activin receptor-like kinase 7) (ALK-7).

STK23_MOUSE
NC score	0.535889 (rank : 812)	θ value	0.00390308 (rank : 970)
Query Neighborhood Hits	1959	Target Neighborhood Hits	572	Shared Neighborhood Hits	557
SwissProt Accessions	Q9Z0G2	Gene names	Stk23, Mssk1
Domain Architecture
Description	Serine/threonine-protein kinase 23 (EC 2.7.11.1) (Muscle-specific serine kinase 1) (MSSK-1).

SRPK2_MOUSE
NC score	0.535838 (rank : 813)	θ value	0.000786445 (rank : 913)
Query Neighborhood Hits	1959	Target Neighborhood Hits	765	Shared Neighborhood Hits	587
SwissProt Accessions	O54781, Q8VCD9	Gene names	Srpk2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SRPK2 (EC 2.7.11.1) (Serine/arginine- rich protein-specific kinase 2) (SR-protein-specific kinase 2) (SFRS protein kinase 2).

STK23_HUMAN
NC score	0.535483 (rank : 814)	θ value	0.00390308 (rank : 969)
Query Neighborhood Hits	1959	Target Neighborhood Hits	556	Shared Neighborhood Hits	551
SwissProt Accessions	Q9UPE1, Q13583, Q9UM62	Gene names	STK23, MSSK1
Domain Architecture
Description	Serine/threonine-protein kinase 23 (EC 2.7.11.1) (Muscle-specific serine kinase 1) (MSSK-1).

MLKL_HUMAN
NC score	0.527220 (rank : 815)	θ value	θ > 10 (rank : 2050)
Query Neighborhood Hits	1959	Target Neighborhood Hits	600	Shared Neighborhood Hits	565
SwissProt Accessions	Q8NB16, Q8N6V0	Gene names	MLKL
Domain Architecture	No domain graphic available
Description	Mixed lineage kinase domain-like protein.

GUC2F_HUMAN
NC score	0.511085 (rank : 816)	θ value	0.00298849 (rank : 952)
Query Neighborhood Hits	1959	Target Neighborhood Hits	740	Shared Neighborhood Hits	668
SwissProt Accessions	P51841, Q9UJF1	Gene names	GUCY2F, GUC2F, RETGC2
Domain Architecture
Description	Retinal guanylyl cyclase 2 precursor (EC 4.6.1.2) (Guanylate cyclase 2F, retinal) (RETGC-2) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2) (Guanylate cyclase F) (GC-F).

AMHR2_HUMAN
NC score	0.498217 (rank : 817)	θ value	θ > 10 (rank : 1965)
Query Neighborhood Hits	1959	Target Neighborhood Hits	715	Shared Neighborhood Hits	658
SwissProt Accessions	Q16671, Q13762	Gene names	AMHR2, AMHR
Domain Architecture
Description	Anti-Muellerian hormone type-2 receptor precursor (EC 2.7.11.30) (Anti-Muellerian hormone type II receptor) (AMH type II receptor) (MIS type II receptor) (MISRII) (MRII).

VRK1_MOUSE
NC score	0.487504 (rank : 818)	θ value	8.40245e-06 (rank : 782)
Query Neighborhood Hits	1959	Target Neighborhood Hits	583	Shared Neighborhood Hits	573
SwissProt Accessions	Q80X41, O88635, O88636, Q8C2P7, Q91YH9	Gene names	Vrk1
Domain Architecture
Description	Serine/threonine-protein kinase VRK1 (EC 2.7.11.1) (Vaccinia-related kinase 1) (Serine/threonine-protein kinase 51PK).

VRK2_MOUSE
NC score	0.482602 (rank : 819)	θ value	0.0193708 (rank : 1024)
Query Neighborhood Hits	1959	Target Neighborhood Hits	586	Shared Neighborhood Hits	575
SwissProt Accessions	Q8BN21, Q5F1Z5, Q5SP88, Q8BPU8, Q8CJ46, Q91WS1, Q9CZF9	Gene names	Vrk2
Domain Architecture
Description	Serine/threonine-protein kinase VRK2 (EC 2.7.11.1) (Vaccinia-related kinase 2).

VRK1_HUMAN
NC score	0.481884 (rank : 820)	θ value	5.44631e-05 (rank : 831)
Query Neighborhood Hits	1959	Target Neighborhood Hits	584	Shared Neighborhood Hits	573
SwissProt Accessions	Q99986	Gene names	VRK1
Domain Architecture
Description	Serine/threonine-protein kinase VRK1 (EC 2.7.11.1) (Vaccinia-related kinase 1).

VRK2_HUMAN
NC score	0.480565 (rank : 821)	θ value	0.00134147 (rank : 931)
Query Neighborhood Hits	1959	Target Neighborhood Hits	582	Shared Neighborhood Hits	559
SwissProt Accessions	Q86Y07, Q49AK9, Q53EU9, Q86Y08, Q86Y09, Q86Y10, Q86Y11, Q86Y12, Q8IXI5, Q99987	Gene names	VRK2
Domain Architecture
Description	Serine/threonine-protein kinase VRK2 (EC 2.7.11.1) (Vaccinia-related kinase 2).

NRBP_HUMAN
NC score	0.470572 (rank : 822)	θ value	0.00298849 (rank : 958)
Query Neighborhood Hits	1959	Target Neighborhood Hits	448	Shared Neighborhood Hits	420
SwissProt Accessions	Q9UHY1, Q53FZ5, Q96SU3	Gene names	NRBP1, BCON3, NRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor-binding protein.

NRBP_MOUSE
NC score	0.468910 (rank : 823)	θ value	0.00175202 (rank : 936)
Query Neighborhood Hits	1959	Target Neighborhood Hits	442	Shared Neighborhood Hits	415
SwissProt Accessions	Q99J45, Q8BL77	Gene names	Nrbp1, Madm, Nrbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor-binding protein (MLF1 adapter molecule) (HLS7- interacting protein kinase).

TEX14_MOUSE
NC score	0.465645 (rank : 824)	θ value	θ > 10 (rank : 2106)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1333	Shared Neighborhood Hits	697
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

GUC2D_HUMAN
NC score	0.464056 (rank : 825)	θ value	0.0193708 (rank : 1017)
Query Neighborhood Hits	1959	Target Neighborhood Hits	715	Shared Neighborhood Hits	655
SwissProt Accessions	Q02846, Q6LEA7	Gene names	GUCY2D, CORD6, GUC1A4, GUC2D, RETGC, RETGC1
Domain Architecture
Description	Retinal guanylyl cyclase 1 precursor (EC 4.6.1.2) (Guanylate cyclase 2D, retinal) (RETGC-1) (Rod outer segment membrane guanylate cyclase) (ROS-GC).

GUC2C_HUMAN
NC score	0.458266 (rank : 826)	θ value	4.03905 (rank : 1660)
Query Neighborhood Hits	1959	Target Neighborhood Hits	624	Shared Neighborhood Hits	573
SwissProt Accessions	P25092	Gene names	GUCY2C, GUC2C, STAR
Domain Architecture
Description	Heat-stable enterotoxin receptor precursor (GC-C) (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) (hSTAR).

GUC2G_MOUSE
NC score	0.443614 (rank : 827)	θ value	0.0563607 (rank : 1072)
Query Neighborhood Hits	1959	Target Neighborhood Hits	644	Shared Neighborhood Hits	572
SwissProt Accessions	Q6TL19, Q8BWU7	Gene names	Gucy2g
Domain Architecture	No domain graphic available
Description	Guanylate cyclase 2G precursor (EC 4.6.1.2) (Guanylyl cyclase receptor G) (mGC-G).

ANPRB_HUMAN
NC score	0.443216 (rank : 828)	θ value	θ > 10 (rank : 1967)
Query Neighborhood Hits	1959	Target Neighborhood Hits	646	Shared Neighborhood Hits	571
SwissProt Accessions	P20594, O60871, Q9UQ50	Gene names	NPR2, ANPRB
Domain Architecture
Description	Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor).

GUC2E_MOUSE
NC score	0.442430 (rank : 829)	θ value	0.0961366 (rank : 1105)
Query Neighborhood Hits	1959	Target Neighborhood Hits	692	Shared Neighborhood Hits	627
SwissProt Accessions	P52785	Gene names	Gucy2e, Guc2e
Domain Architecture
Description	Guanylyl cyclase GC-E precursor (EC 4.6.1.2) (Guanylate cyclase 2E).

TEX14_HUMAN
NC score	0.426905 (rank : 830)	θ value	θ > 10 (rank : 2105)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1103	Shared Neighborhood Hits	646
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

OBSL1_HUMAN
NC score	0.423459 (rank : 831)	θ value	3.37985e-39 (rank : 20)
Query Neighborhood Hits	1959	Target Neighborhood Hits	354	Shared Neighborhood Hits	270
SwissProt Accessions	O75147, Q96IW3	Gene names	OBSL1, KIAA0657
Domain Architecture	No domain graphic available
Description	Obscurin-like protein 1 precursor.

ANPRB_MOUSE
NC score	0.416962 (rank : 832)	θ value	θ > 10 (rank : 1968)
Query Neighborhood Hits	1959	Target Neighborhood Hits	607	Shared Neighborhood Hits	545
SwissProt Accessions	Q6VVW5, Q6VVW3, Q6VVW4, Q8CGA9	Gene names	Npr2
Domain Architecture	No domain graphic available
Description	Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor).

ANPRA_MOUSE
NC score	0.412359 (rank : 833)	θ value	0.163984 (rank : 1135)
Query Neighborhood Hits	1959	Target Neighborhood Hits	600	Shared Neighborhood Hits	527
SwissProt Accessions	P18293	Gene names	Npr1, Npra
Domain Architecture
Description	Atrial natriuretic peptide receptor A precursor (ANP-A) (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor).

ANPRA_HUMAN
NC score	0.412253 (rank : 834)	θ value	0.0961366 (rank : 1100)
Query Neighborhood Hits	1959	Target Neighborhood Hits	612	Shared Neighborhood Hits	535
SwissProt Accessions	P16066, Q6P4Q3	Gene names	NPR1, ANPRA
Domain Architecture
Description	Atrial natriuretic peptide receptor A precursor (ANP-A) (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor).

ROBO1_MOUSE
NC score	0.408675 (rank : 835)	θ value	4.28545e-26 (rank : 71)
Query Neighborhood Hits	1959	Target Neighborhood Hits	559	Shared Neighborhood Hits	362
SwissProt Accessions	O89026	Gene names	Robo1, Dutt1
Domain Architecture
Description	Roundabout homolog 1 precursor.

ROBO1_HUMAN
NC score	0.408671 (rank : 836)	θ value	1.47289e-26 (rank : 65)
Query Neighborhood Hits	1959	Target Neighborhood Hits	529	Shared Neighborhood Hits	342
SwissProt Accessions	Q9Y6N7, Q7Z300, Q9BUS7	Gene names	ROBO1, DUTT1
Domain Architecture
Description	Roundabout homolog 1 precursor (H-Robo-1) (Deleted in U twenty twenty).

ROBO3_HUMAN
NC score	0.408318 (rank : 837)	θ value	1.37858e-24 (rank : 88)
Query Neighborhood Hits	1959	Target Neighborhood Hits	570	Shared Neighborhood Hits	388
SwissProt Accessions	Q96MS0	Gene names	ROBO3
Domain Architecture
Description	Roundabout homolog 3 precursor (Roundabout-like protein 3).

ILK1_HUMAN
NC score	0.408234 (rank : 838)	θ value	θ > 10 (rank : 2037)
Query Neighborhood Hits	1959	Target Neighborhood Hits	857	Shared Neighborhood Hits	585
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

ROBO2_HUMAN
NC score	0.407886 (rank : 839)	θ value	3.17079e-29 (rank : 48)
Query Neighborhood Hits	1959	Target Neighborhood Hits	479	Shared Neighborhood Hits	323
SwissProt Accessions	Q9HCK4, O43608	Gene names	ROBO2, KIAA1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

MYPN_HUMAN
NC score	0.407559 (rank : 840)	θ value	6.84181e-24 (rank : 96)
Query Neighborhood Hits	1959	Target Neighborhood Hits	418	Shared Neighborhood Hits	324
SwissProt Accessions	Q86TC9, Q5VV35, Q5VV36, Q86T37, Q8N3L4, Q96K90, Q96KF5	Gene names	MYPN, MYOP
Domain Architecture	No domain graphic available
Description	Myopalladin (145 kDa sarcomeric protein).

ROBO2_MOUSE
NC score	0.407304 (rank : 841)	θ value	1.85889e-29 (rank : 46)
Query Neighborhood Hits	1959	Target Neighborhood Hits	504	Shared Neighborhood Hits	332
SwissProt Accessions	Q7TPD3, Q8BJ59	Gene names	Robo2, Kiaa1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

ILK_MOUSE
NC score	0.406103 (rank : 842)	θ value	θ > 10 (rank : 2039)
Query Neighborhood Hits	1959	Target Neighborhood Hits	858	Shared Neighborhood Hits	586
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

MYPN_MOUSE
NC score	0.405163 (rank : 843)	θ value	8.93572e-24 (rank : 103)
Query Neighborhood Hits	1959	Target Neighborhood Hits	421	Shared Neighborhood Hits	315
SwissProt Accessions	Q5DTJ9, Q7TPW5, Q8BZ76	Gene names	Mypn, Kiaa4170
Domain Architecture	No domain graphic available
Description	Myopalladin.

BUB1_HUMAN
NC score	0.405156 (rank : 844)	θ value	0.0563607 (rank : 1068)
Query Neighborhood Hits	1959	Target Neighborhood Hits	543	Shared Neighborhood Hits	426
SwissProt Accessions	O43683, O43430, O43643, O60626	Gene names	BUB1, BUB1L
Domain Architecture
Description	Mitotic checkpoint serine/threonine-protein kinase BUB1 (EC 2.7.11.1) (hBUB1) (BUB1A).

ROBO3_MOUSE
NC score	0.404887 (rank : 845)	θ value	1.02238e-19 (rank : 185)
Query Neighborhood Hits	1959	Target Neighborhood Hits	524	Shared Neighborhood Hits	370
SwissProt Accessions	Q9Z2I4	Gene names	Robo3, Rbig1
Domain Architecture
Description	Roundabout homolog 3 precursor (Retinoblastoma-inhibiting gene 1) (Rig-1).

PUNC_MOUSE
NC score	0.402941 (rank : 846)	θ value	8.65492e-19 (rank : 201)
Query Neighborhood Hits	1959	Target Neighborhood Hits	501	Shared Neighborhood Hits	348
SwissProt Accessions	Q8BQC3, O70246, Q792T2, Q9Z2S6	Gene names	Punc
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

PUNC_HUMAN
NC score	0.402479 (rank : 847)	θ value	9.24701e-21 (rank : 157)
Query Neighborhood Hits	1959	Target Neighborhood Hits	449	Shared Neighborhood Hits	308
SwissProt Accessions	Q8IVU1, O95215	Gene names	PUNC
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

MYOTI_HUMAN
NC score	0.400311 (rank : 848)	θ value	9.90251e-15 (rank : 386)
Query Neighborhood Hits	1959	Target Neighborhood Hits	292	Shared Neighborhood Hits	257
SwissProt Accessions	Q9UBF9	Gene names	MYOT, TTID
Domain Architecture	No domain graphic available
Description	Myotilin (Titin immunoglobulin domain protein) (Myofibrillar titin- like Ig domains protein) (57 kDa cytoskeletal protein).

DCC_MOUSE
NC score	0.400187 (rank : 849)	θ value	7.30988e-26 (rank : 73)
Query Neighborhood Hits	1959	Target Neighborhood Hits	896	Shared Neighborhood Hits	545
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

MYOTI_MOUSE
NC score	0.399315 (rank : 850)	θ value	5.8054e-15 (rank : 370)
Query Neighborhood Hits	1959	Target Neighborhood Hits	297	Shared Neighborhood Hits	258
SwissProt Accessions	Q9JIF9	Gene names	Myot, Ttid
Domain Architecture	No domain graphic available
Description	Myotilin (Titin immunoglobulin domain protein) (Myofibrillar titin- like Ig domains protein).

DSCL1_HUMAN
NC score	0.397813 (rank : 851)	θ value	4.15078e-21 (rank : 150)
Query Neighborhood Hits	1959	Target Neighborhood Hits	589	Shared Neighborhood Hits	386
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

BOC_MOUSE
NC score	0.397707 (rank : 852)	θ value	1.2077e-20 (rank : 159)
Query Neighborhood Hits	1959	Target Neighborhood Hits	433	Shared Neighborhood Hits	320
SwissProt Accessions	Q6AZB0, Q6KAM5, Q6P5H3, Q7TMJ3, Q8CE73, Q8CE91, Q8R377, Q923W7	Gene names	Boc
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

DCC_HUMAN
NC score	0.396758 (rank : 853)	θ value	7.30988e-26 (rank : 72)
Query Neighborhood Hits	1959	Target Neighborhood Hits	583	Shared Neighborhood Hits	398
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

BOC_HUMAN
NC score	0.395793 (rank : 854)	θ value	5.60996e-18 (rank : 227)
Query Neighborhood Hits	1959	Target Neighborhood Hits	543	Shared Neighborhood Hits	353
SwissProt Accessions	Q9BWV1, Q6UXJ5, Q8N2P7, Q8NF26	Gene names	BOC
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

NCAM2_MOUSE
NC score	0.395579 (rank : 855)	θ value	2.97466e-19 (rank : 193)
Query Neighborhood Hits	1959	Target Neighborhood Hits	472	Shared Neighborhood Hits	332
SwissProt Accessions	O35136, O35962	Gene names	Ncam2, Ocam, Rncam
Domain Architecture
Description	Neural cell adhesion molecule 2 precursor (N-CAM 2) (RB-8 neural cell adhesion molecule) (R4B12).

NFASC_MOUSE
NC score	0.395441 (rank : 856)	θ value	1.29031e-22 (rank : 124)
Query Neighborhood Hits	1959	Target Neighborhood Hits	475	Shared Neighborhood Hits	349
SwissProt Accessions	Q810U3	Gene names	Nfasc
Domain Architecture
Description	Neurofascin precursor.

ILK2_HUMAN
NC score	0.395238 (rank : 857)	θ value	θ > 10 (rank : 2038)
Query Neighborhood Hits	1959	Target Neighborhood Hits	848	Shared Neighborhood Hits	577
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

DSCAM_HUMAN
NC score	0.394961 (rank : 858)	θ value	1.5773e-20 (rank : 163)
Query Neighborhood Hits	1959	Target Neighborhood Hits	524	Shared Neighborhood Hits	347
SwissProt Accessions	O60469, O60468	Gene names	DSCAM
Domain Architecture
Description	Down syndrome cell adhesion molecule precursor (CHD2).

NFASC_HUMAN
NC score	0.394069 (rank : 859)	θ value	3.39556e-23 (rank : 112)
Query Neighborhood Hits	1959	Target Neighborhood Hits	497	Shared Neighborhood Hits	354
SwissProt Accessions	O94856, Q5T2F0, Q5T2F1, Q5T2F2, Q5T2F3, Q5T2F4, Q5T2F5, Q5T2F6, Q5T2F7, Q5T2F9, Q5T2G0, Q5W9F8, Q68DH3, Q6ZQV6, Q7Z3K1, Q96HT1, Q96K50	Gene names	NFASC, KIAA0756
Domain Architecture
Description	Neurofascin precursor.

NCAM2_HUMAN
NC score	0.394046 (rank : 860)	θ value	2.7842e-17 (rank : 258)
Query Neighborhood Hits	1959	Target Neighborhood Hits	441	Shared Neighborhood Hits	327
SwissProt Accessions	O15394	Gene names	NCAM2, NCAM21
Domain Architecture
Description	Neural cell adhesion molecule 2 precursor (N-CAM 2).

NEO1_HUMAN
NC score	0.393573 (rank : 861)	θ value	3.75424e-22 (rank : 136)
Query Neighborhood Hits	1959	Target Neighborhood Hits	530	Shared Neighborhood Hits	346
SwissProt Accessions	Q92859, O00340	Gene names	NEO1, NGN
Domain Architecture
Description	Neogenin precursor.

NEO1_MOUSE
NC score	0.393056 (rank : 862)	θ value	1.6852e-22 (rank : 127)
Query Neighborhood Hits	1959	Target Neighborhood Hits	523	Shared Neighborhood Hits	349
SwissProt Accessions	P97798	Gene names	Neo1, Ngn
Domain Architecture
Description	Neogenin precursor.

CNTN5_HUMAN
NC score	0.392445 (rank : 863)	θ value	8.36355e-22 (rank : 141)
Query Neighborhood Hits	1959	Target Neighborhood Hits	446	Shared Neighborhood Hits	334
SwissProt Accessions	O94779, O94780	Gene names	CNTN5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2) (hNB-2).

FGRL1_HUMAN
NC score	0.391143 (rank : 864)	θ value	9.90251e-15 (rank : 382)
Query Neighborhood Hits	1959	Target Neighborhood Hits	335	Shared Neighborhood Hits	272
SwissProt Accessions	Q8N441, Q6PJN1, Q9BXN7, Q9H4D7	Gene names	FGFRL1, FGFR5, FHFR
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5) (FGFR-like protein) (FGF homologous factor receptor).

CNTN4_MOUSE
NC score	0.390386 (rank : 865)	θ value	9.54697e-26 (rank : 75)
Query Neighborhood Hits	1959	Target Neighborhood Hits	445	Shared Neighborhood Hits	316
SwissProt Accessions	Q69Z26, Q8BRT6, Q8CBD3	Gene names	Cntn4, Kiaa3024
Domain Architecture	No domain graphic available
Description	Contactin-4 precursor (Brain-derived immunoglobulin superfamily protein 2) (BIG-2).

FGRL1_MOUSE
NC score	0.390220 (rank : 866)	θ value	1.29331e-14 (rank : 389)
Query Neighborhood Hits	1959	Target Neighborhood Hits	325	Shared Neighborhood Hits	275
SwissProt Accessions	Q91V87, Q920C2, Q920C3	Gene names	Fgfrl1, Fgfr5
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5).

NCA11_MOUSE
NC score	0.390058 (rank : 867)	θ value	1.58096e-12 (rank : 481)
Query Neighborhood Hits	1959	Target Neighborhood Hits	661	Shared Neighborhood Hits	438
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

CNTN4_HUMAN
NC score	0.389963 (rank : 868)	θ value	4.28545e-26 (rank : 70)
Query Neighborhood Hits	1959	Target Neighborhood Hits	449	Shared Neighborhood Hits	318
SwissProt Accessions	Q8IWV2, Q8IX14, Q8TC35	Gene names	CNTN4
Domain Architecture	No domain graphic available
Description	Contactin-4 precursor (Brain-derived immunoglobulin superfamily protein 2) (BIG-2).

NCA12_HUMAN
NC score	0.389127 (rank : 869)	θ value	3.76295e-14 (rank : 422)
Query Neighborhood Hits	1959	Target Neighborhood Hits	437	Shared Neighborhood Hits	323
SwissProt Accessions	P13592, P13593	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120) (CD56 antigen).

CNTN5_MOUSE
NC score	0.388772 (rank : 870)	θ value	1.02238e-19 (rank : 184)
Query Neighborhood Hits	1959	Target Neighborhood Hits	434	Shared Neighborhood Hits	332
SwissProt Accessions	P68500	Gene names	Cntn5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2).

CDON_HUMAN
NC score	0.388675 (rank : 871)	θ value	6.00763e-12 (rank : 513)
Query Neighborhood Hits	1959	Target Neighborhood Hits	412	Shared Neighborhood Hits	297
SwissProt Accessions	Q4KMG0, O14631	Gene names	CDON, CDO
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

NCA11_HUMAN
NC score	0.388444 (rank : 872)	θ value	1.29331e-14 (rank : 394)
Query Neighborhood Hits	1959	Target Neighborhood Hits	443	Shared Neighborhood Hits	327
SwissProt Accessions	P13591, Q15829, Q16180	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 140 kDa isoform precursor (N-CAM 140) (NCAM-140) (CD56 antigen).

L1CAM_HUMAN
NC score	0.388443 (rank : 873)	θ value	4.15078e-21 (rank : 151)
Query Neighborhood Hits	1959	Target Neighborhood Hits	457	Shared Neighborhood Hits	331
SwissProt Accessions	P32004, Q8TA87	Gene names	L1CAM, CAML1, MIC5
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

CDON_MOUSE
NC score	0.387859 (rank : 874)	θ value	3.89403e-11 (rank : 536)
Query Neighborhood Hits	1959	Target Neighborhood Hits	410	Shared Neighborhood Hits	308
SwissProt Accessions	Q32MD9, O88971	Gene names	Cdon, Cdo
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

CNTN2_HUMAN
NC score	0.387822 (rank : 875)	θ value	1.80466e-16 (rank : 294)
Query Neighborhood Hits	1959	Target Neighborhood Hits	440	Shared Neighborhood Hits	331
SwissProt Accessions	Q02246, P78432	Gene names	CNTN2, TAG1, TAX1
Domain Architecture
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

L1CAM_MOUSE
NC score	0.387269 (rank : 876)	θ value	9.24701e-21 (rank : 155)
Query Neighborhood Hits	1959	Target Neighborhood Hits	457	Shared Neighborhood Hits	328
SwissProt Accessions	P11627	Gene names	L1cam, Caml1
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

CNTN2_MOUSE
NC score	0.387246 (rank : 877)	θ value	4.74913e-17 (rank : 269)
Query Neighborhood Hits	1959	Target Neighborhood Hits	450	Shared Neighborhood Hits	335
SwissProt Accessions	Q61330, Q6NZJ4, Q7TSJ5	Gene names	Cntn2, Tax
Domain Architecture	No domain graphic available
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

CNTN3_HUMAN
NC score	0.386320 (rank : 878)	θ value	2.06002e-20 (rank : 164)
Query Neighborhood Hits	1959	Target Neighborhood Hits	455	Shared Neighborhood Hits	325
SwissProt Accessions	Q9P232, Q9H039	Gene names	CNTN3, KIAA1496, PANG
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

CNTN6_MOUSE
NC score	0.386297 (rank : 879)	θ value	8.93572e-24 (rank : 100)
Query Neighborhood Hits	1959	Target Neighborhood Hits	429	Shared Neighborhood Hits	313
SwissProt Accessions	Q9JMB8, Q8C6X1	Gene names	Cntn6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (mNB-3).

NRCAM_MOUSE
NC score	0.385826 (rank : 880)	θ value	4.58923e-20 (rank : 179)
Query Neighborhood Hits	1959	Target Neighborhood Hits	432	Shared Neighborhood Hits	325
SwissProt Accessions	Q810U4, Q80U33, Q8BLG8, Q8BX92, Q8BYJ8	Gene names	Nrcam, Kiaa0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (mBravo).

NCA12_MOUSE
NC score	0.385725 (rank : 881)	θ value	1.58096e-12 (rank : 482)
Query Neighborhood Hits	1959	Target Neighborhood Hits	399	Shared Neighborhood Hits	307
SwissProt Accessions	P13594, Q61950	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120).

CNTN6_HUMAN
NC score	0.384260 (rank : 882)	θ value	1.29031e-22 (rank : 122)
Query Neighborhood Hits	1959	Target Neighborhood Hits	422	Shared Neighborhood Hits	309
SwissProt Accessions	Q9UQ52	Gene names	CNTN6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (hNB-3).

CNTN1_MOUSE
NC score	0.383716 (rank : 883)	θ value	7.82807e-20 (rank : 183)
Query Neighborhood Hits	1959	Target Neighborhood Hits	422	Shared Neighborhood Hits	316
SwissProt Accessions	P12960, Q6NXV7, Q8BR42, Q8C6A0	Gene names	Cntn1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3).

CNTN3_MOUSE
NC score	0.383239 (rank : 884)	θ value	1.42661e-21 (rank : 146)
Query Neighborhood Hits	1959	Target Neighborhood Hits	447	Shared Neighborhood Hits	320
SwissProt Accessions	Q07409	Gene names	Cntn3, Pang, Pcs
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

CNTN1_HUMAN
NC score	0.383183 (rank : 885)	θ value	5.07402e-19 (rank : 195)
Query Neighborhood Hits	1959	Target Neighborhood Hits	431	Shared Neighborhood Hits	316
SwissProt Accessions	Q12860, Q12861, Q14030, Q8N466	Gene names	CNTN1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3) (Glycoprotein gp135).

NRCAM_HUMAN
NC score	0.382618 (rank : 886)	θ value	6.20254e-17 (rank : 274)
Query Neighborhood Hits	1959	Target Neighborhood Hits	439	Shared Neighborhood Hits	329
SwissProt Accessions	Q92823, O15051, O15179, Q9UHI3, Q9UHI4	Gene names	NRCAM, KIAA0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (hBravo).

SDK1_HUMAN
NC score	0.382347 (rank : 887)	θ value	9.56915e-18 (rank : 241)
Query Neighborhood Hits	1959	Target Neighborhood Hits	511	Shared Neighborhood Hits	353
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

SDK1_MOUSE
NC score	0.380126 (rank : 888)	θ value	8.10077e-17 (rank : 280)
Query Neighborhood Hits	1959	Target Neighborhood Hits	495	Shared Neighborhood Hits	344
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

SDK2_HUMAN
NC score	0.378280 (rank : 889)	θ value	7.58209e-15 (rank : 377)
Query Neighborhood Hits	1959	Target Neighborhood Hits	495	Shared Neighborhood Hits	345
SwissProt Accessions	Q58EX2, Q86VY3, Q9NTD2, Q9NVB3, Q9P214	Gene names	SDK2, KIAA1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

SDK2_MOUSE
NC score	0.377391 (rank : 890)	θ value	4.02038e-16 (rank : 314)
Query Neighborhood Hits	1959	Target Neighborhood Hits	480	Shared Neighborhood Hits	346
SwissProt Accessions	Q6V4S5, Q3TTK1, Q5U5W7, Q6ZPP2	Gene names	Sdk2, Kiaa1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

CHL1_HUMAN
NC score	0.376655 (rank : 891)	θ value	1.74796e-11 (rank : 529)
Query Neighborhood Hits	1959	Target Neighborhood Hits	413	Shared Neighborhood Hits	317
SwissProt Accessions	O00533, Q2M3G2, Q59FY0	Gene names	CHL1, CALL
Domain Architecture	No domain graphic available
Description	Neural cell adhesion molecule L1-like protein precursor (Close homolog of L1).

CHL1_MOUSE
NC score	0.376595 (rank : 892)	θ value	7.09661e-13 (rank : 470)
Query Neighborhood Hits	1959	Target Neighborhood Hits	402	Shared Neighborhood Hits	310
SwissProt Accessions	P70232, Q8BS24, Q8C6W0, Q8C823, Q8VBY7	Gene names	Chl1, Call
Domain Architecture	No domain graphic available
Description	Neural cell adhesion molecule L1-like protein precursor (Cell adhesion molecule with homology to L1CAM) (Close homolog of L1) (Chl1-like protein).

LSAMP_HUMAN
NC score	0.370071 (rank : 893)	θ value	1.29331e-14 (rank : 392)
Query Neighborhood Hits	1959	Target Neighborhood Hits	347	Shared Neighborhood Hits	275
SwissProt Accessions	Q13449, Q8IV49	Gene names	LSAMP, LAMP
Domain Architecture
Description	Limbic system-associated membrane protein precursor (LSAMP).

LSAMP_MOUSE
NC score	0.369967 (rank : 894)	θ value	1.29331e-14 (rank : 393)
Query Neighborhood Hits	1959	Target Neighborhood Hits	344	Shared Neighborhood Hits	274
SwissProt Accessions	Q8BLK3	Gene names	Lsamp
Domain Architecture	No domain graphic available
Description	Limbic system-associated membrane protein precursor (LSAMP).

OPCM_HUMAN
NC score	0.367533 (rank : 895)	θ value	9.26847e-13 (rank : 474)
Query Neighborhood Hits	1959	Target Neighborhood Hits	332	Shared Neighborhood Hits	276
SwissProt Accessions	Q14982	Gene names	OPCML, OBCAM
Domain Architecture
Description	Opioid-binding protein/cell adhesion molecule precursor (OBCAM) (Opioid-binding cell adhesion molecule) (OPCML).

PI3R4_MOUSE
NC score	0.364956 (rank : 896)	θ value	0.163984 (rank : 1142)
Query Neighborhood Hits	1959	Target Neighborhood Hits	535	Shared Neighborhood Hits	362
SwissProt Accessions	Q8VD65, Q56A65, Q8C948, Q8C9D7, Q9CVC5	Gene names	Pik3r4
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 4 (EC 2.7.11.1) (PI3- kinase regulatory subunit 4).

MYPC1_HUMAN
NC score	0.364753 (rank : 897)	θ value	2.43343e-21 (rank : 148)
Query Neighborhood Hits	1959	Target Neighborhood Hits	303	Shared Neighborhood Hits	257
SwissProt Accessions	Q00872, Q15497	Gene names	MYBPC1, MYBPCS
Domain Architecture
Description	Myosin-binding protein C, slow-type (Slow MyBP-C) (C-protein, skeletal muscle slow isoform).

ROBO4_MOUSE
NC score	0.361433 (rank : 898)	θ value	1.29631e-06 (rank : 748)
Query Neighborhood Hits	1959	Target Neighborhood Hits	358	Shared Neighborhood Hits	281
SwissProt Accessions	Q8C310, Q9DBW1	Gene names	Robo4
Domain Architecture
Description	Roundabout homolog 4 precursor.

NTRI_MOUSE
NC score	0.359909 (rank : 899)	θ value	3.29651e-10 (rank : 574)
Query Neighborhood Hits	1959	Target Neighborhood Hits	342	Shared Neighborhood Hits	278
SwissProt Accessions	Q99PJ0	Gene names	Nt, Hnt
Domain Architecture
Description	Neurotrimin precursor.

NTRI_HUMAN
NC score	0.358938 (rank : 900)	θ value	3.29651e-10 (rank : 573)
Query Neighborhood Hits	1959	Target Neighborhood Hits	344	Shared Neighborhood Hits	279
SwissProt Accessions	Q9P121, Q6UXJ3, Q86VJ9	Gene names	NT
Domain Architecture
Description	Neurotrimin precursor (hNT).

NEGR1_HUMAN
NC score	0.358912 (rank : 901)	θ value	1.25267e-09 (rank : 596)
Query Neighborhood Hits	1959	Target Neighborhood Hits	346	Shared Neighborhood Hits	269
SwissProt Accessions	Q7Z3B1, Q5VT21, Q6UY06, Q8NAQ3	Gene names	NEGR1
Domain Architecture	No domain graphic available
Description	Neuronal growth regulator 1 precursor.

NEGR1_MOUSE
NC score	0.358445 (rank : 902)	θ value	3.64472e-09 (rank : 606)
Query Neighborhood Hits	1959	Target Neighborhood Hits	349	Shared Neighborhood Hits	270
SwissProt Accessions	Q80Z24, Q3UHQ8, Q80T70	Gene names	Negr1, Kiaa3001, Ntra
Domain Architecture	No domain graphic available
Description	Neuronal growth regulator 1 precursor (Kilon protein) (Kindred of IgLON) (Neurotractin).

MYPC2_HUMAN
NC score	0.357904 (rank : 903)	θ value	1.92812e-18 (rank : 216)
Query Neighborhood Hits	1959	Target Neighborhood Hits	316	Shared Neighborhood Hits	263
SwissProt Accessions	Q14324	Gene names	MYBPC2, MYBPCF
Domain Architecture
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

ROBO4_HUMAN
NC score	0.357853 (rank : 904)	θ value	1.43324e-05 (rank : 794)
Query Neighborhood Hits	1959	Target Neighborhood Hits	364	Shared Neighborhood Hits	292
SwissProt Accessions	Q8WZ75, Q8TEG1, Q96JV6, Q9H718, Q9NWJ8	Gene names	ROBO4
Domain Architecture
Description	Roundabout homolog 4 precursor (Magic roundabout).

MYOM2_HUMAN
NC score	0.355730 (rank : 905)	θ value	1.02475e-11 (rank : 522)
Query Neighborhood Hits	1959	Target Neighborhood Hits	341	Shared Neighborhood Hits	267
SwissProt Accessions	P54296	Gene names	MYOM2
Domain Architecture
Description	Myomesin-2 (M-protein) (165 kDa titin-associated protein) (165 kDa connectin-associated protein).

MAMC1_HUMAN
NC score	0.354241 (rank : 906)	θ value	6.21693e-09 (rank : 616)
Query Neighborhood Hits	1959	Target Neighborhood Hits	357	Shared Neighborhood Hits	271
SwissProt Accessions	Q7Z553	Gene names	MAMDC1, MDGA2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

MAMC1_MOUSE
NC score	0.353541 (rank : 907)	θ value	4.76016e-09 (rank : 608)
Query Neighborhood Hits	1959	Target Neighborhood Hits	357	Shared Neighborhood Hits	270
SwissProt Accessions	P60755	Gene names	Mamdc1, Mdga2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

MYOM1_MOUSE
NC score	0.353208 (rank : 908)	θ value	2.88119e-14 (rank : 417)
Query Neighborhood Hits	1959	Target Neighborhood Hits	415	Shared Neighborhood Hits	296
SwissProt Accessions	Q62234	Gene names	Myom1
Domain Architecture
Description	Myomesin-1 (Skelemin).

MYPC2_MOUSE
NC score	0.352339 (rank : 909)	θ value	4.44505e-15 (rank : 368)
Query Neighborhood Hits	1959	Target Neighborhood Hits	297	Shared Neighborhood Hits	250
SwissProt Accessions	Q5XKE0, Q8C109, Q8K2V0	Gene names	Mybpc2
Domain Architecture	No domain graphic available
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

MDGA1_HUMAN
NC score	0.352297 (rank : 910)	θ value	3.76295e-14 (rank : 421)
Query Neighborhood Hits	1959	Target Neighborhood Hits	358	Shared Neighborhood Hits	274
SwissProt Accessions	Q8NFP4, Q8NBE3	Gene names	MDGA1, MAMDC3
Domain Architecture
Description	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 precursor (MAM domain-containing protein 3) (GPI and MAM protein) (Glycosylphosphatidylinositol-MAM) (GPIM).

MYPC3_MOUSE
NC score	0.350953 (rank : 911)	θ value	9.56915e-18 (rank : 238)
Query Neighborhood Hits	1959	Target Neighborhood Hits	310	Shared Neighborhood Hits	260
SwissProt Accessions	O70468, O88997	Gene names	Mybpc3
Domain Architecture
Description	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform).

PI3R4_HUMAN
NC score	0.349937 (rank : 912)	θ value	0.163984 (rank : 1141)
Query Neighborhood Hits	1959	Target Neighborhood Hits	534	Shared Neighborhood Hits	351
SwissProt Accessions	Q99570	Gene names	PIK3R4
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 4 (EC 2.7.11.1) (PI3- kinase regulatory subunit 4) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein).

MYPC3_HUMAN
NC score	0.348366 (rank : 913)	θ value	1.86753e-13 (rank : 449)
Query Neighborhood Hits	1959	Target Neighborhood Hits	318	Shared Neighborhood Hits	263
SwissProt Accessions	Q14896, Q16410, Q6R2F7, Q9UE27, Q9UM53	Gene names	MYBPC3
Domain Architecture
Description	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform).

MYOM1_HUMAN
NC score	0.346255 (rank : 914)	θ value	1.02475e-11 (rank : 521)
Query Neighborhood Hits	1959	Target Neighborhood Hits	405	Shared Neighborhood Hits	283
SwissProt Accessions	P52179	Gene names	MYOM1
Domain Architecture
Description	Myomesin-1 (190 kDa titin-associated protein) (190 kDa connectin- associated protein).

STK31_HUMAN
NC score	0.342625 (rank : 915)	θ value	1.06291 (rank : 1411)
Query Neighborhood Hits	1959	Target Neighborhood Hits	570	Shared Neighborhood Hits	374
SwissProt Accessions	Q9BXU1, Q9BXH8	Gene names	STK31
Domain Architecture
Description	Serine/threonine-protein kinase 31 (EC 2.7.11.1) (Serine/threonine- protein kinase NYD-SPK).

NPHN_HUMAN
NC score	0.342150 (rank : 916)	θ value	1.69304e-06 (rank : 755)
Query Neighborhood Hits	1959	Target Neighborhood Hits	362	Shared Neighborhood Hits	277
SwissProt Accessions	O60500	Gene names	NPHS1, NPHN
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

VCAM1_MOUSE
NC score	0.341678 (rank : 917)	θ value	1.99992e-07 (rank : 694)
Query Neighborhood Hits	1959	Target Neighborhood Hits	320	Shared Neighborhood Hits	253
SwissProt Accessions	P29533	Gene names	Vcam1, Vcam-1
Domain Architecture
Description	Vascular cell adhesion protein 1 precursor (V-CAM 1).

VCAM1_HUMAN
NC score	0.340304 (rank : 918)	θ value	5.81887e-07 (rank : 728)
Query Neighborhood Hits	1959	Target Neighborhood Hits	352	Shared Neighborhood Hits	249
SwissProt Accessions	P19320, Q6NUP8	Gene names	VCAM1, L1CAM
Domain Architecture
Description	Vascular cell adhesion protein 1 precursor (V-CAM 1) (CD106 antigen) (INCAM-100).

NPHN_MOUSE
NC score	0.335817 (rank : 919)	θ value	4.45536e-07 (rank : 716)
Query Neighborhood Hits	1959	Target Neighborhood Hits	370	Shared Neighborhood Hits	276
SwissProt Accessions	Q9QZS7	Gene names	Nphs1, Nphn
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

NTKL_MOUSE
NC score	0.335263 (rank : 920)	θ value	θ > 10 (rank : 2057)
Query Neighborhood Hits	1959	Target Neighborhood Hits	326	Shared Neighborhood Hits	290
SwissProt Accessions	Q9EQC5, Q3TST7, Q3UKU0, Q8K222	Gene names	Scyl1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like protein (SCY1-like protein 1) (105 kDa kinase- like protein) (Mitosis-associated kinase-like protein NTKL).

MAG_MOUSE
NC score	0.331375 (rank : 921)	θ value	0.000270298 (rank : 876)
Query Neighborhood Hits	1959	Target Neighborhood Hits	271	Shared Neighborhood Hits	243
SwissProt Accessions	P20917, P16880	Gene names	Mag
Domain Architecture
Description	Myelin-associated glycoprotein precursor (Siglec-4a).

MAG_HUMAN
NC score	0.330725 (rank : 922)	θ value	0.000121331 (rank : 849)
Query Neighborhood Hits	1959	Target Neighborhood Hits	278	Shared Neighborhood Hits	244
SwissProt Accessions	P20916	Gene names	MAG
Domain Architecture
Description	Myelin-associated glycoprotein precursor (Siglec-4a).

MYBPH_HUMAN
NC score	0.329098 (rank : 923)	θ value	3.64472e-09 (rank : 605)
Query Neighborhood Hits	1959	Target Neighborhood Hits	256	Shared Neighborhood Hits	238
SwissProt Accessions	Q13203, Q16886, Q86YC5	Gene names	MYBPH
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

MYBPH_MOUSE
NC score	0.327968 (rank : 924)	θ value	7.34386e-10 (rank : 585)
Query Neighborhood Hits	1959	Target Neighborhood Hits	290	Shared Neighborhood Hits	252
SwissProt Accessions	P70402	Gene names	Mybph
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

SN_MOUSE
NC score	0.324800 (rank : 925)	θ value	1.38499e-08 (rank : 633)
Query Neighborhood Hits	1959	Target Neighborhood Hits	416	Shared Neighborhood Hits	277
SwissProt Accessions	Q62230, O55216, Q62228, Q62229	Gene names	Sn, Sa
Domain Architecture
Description	Sialoadhesin precursor (Sialic acid-binding Ig-like lectin-1) (Siglec- 1) (Sheep erythrocyte receptor) (SER) (CD169 antigen).

K2002_HUMAN
NC score	0.322411 (rank : 926)	θ value	1.81305 (rank : 1496)
Query Neighborhood Hits	1959	Target Neighborhood Hits	274	Shared Neighborhood Hits	264
SwissProt Accessions	Q9H792, Q6ZS78, Q8NCM3	Gene names	KIAA2002
Domain Architecture	No domain graphic available
Description	Uncharacterized tyrosine-protein kinase KIAA2002 (EC 2.7.10.2).

SN_HUMAN
NC score	0.321909 (rank : 927)	θ value	4.30538e-10 (rank : 577)
Query Neighborhood Hits	1959	Target Neighborhood Hits	434	Shared Neighborhood Hits	279
SwissProt Accessions	Q9BZZ2, Q96DL4, Q9GZS5, Q9H1H6, Q9H1H7, Q9H7L7	Gene names	SN
Domain Architecture
Description	Sialoadhesin precursor (Sialic acid-binding Ig-like lectin-1) (Siglec- 1) (CD169 antigen).

KIRR2_HUMAN
NC score	0.318533 (rank : 928)	θ value	8.11959e-09 (rank : 620)
Query Neighborhood Hits	1959	Target Neighborhood Hits	321	Shared Neighborhood Hits	238
SwissProt Accessions	Q6UWL6, Q6P1R1, Q7Z5P1, Q7Z5P2, Q96IQ8, Q9H0T1	Gene names	KIRREL2, NEPH3
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2) (Nephrin-like protein 3).

RAGE_HUMAN
NC score	0.318238 (rank : 929)	θ value	0.00020696 (rank : 867)
Query Neighborhood Hits	1959	Target Neighborhood Hits	269	Shared Neighborhood Hits	234
SwissProt Accessions	Q15109, Q15279, Q9H2X7, Q9Y3R3	Gene names	AGER, RAGE
Domain Architecture
Description	Advanced glycosylation end product-specific receptor precursor (Receptor for advanced glycosylation end products).

TMIGD_HUMAN
NC score	0.316773 (rank : 930)	θ value	0.00665767 (rank : 988)
Query Neighborhood Hits	1959	Target Neighborhood Hits	240	Shared Neighborhood Hits	214
SwissProt Accessions	Q6UXZ0, Q6ZMC6	Gene names	TMIGD
Domain Architecture	No domain graphic available
Description	Transmembrane and immunoglobulin domain-containing protein precursor.

FSTL4_HUMAN
NC score	0.315393 (rank : 931)	θ value	1.43324e-05 (rank : 789)
Query Neighborhood Hits	1959	Target Neighborhood Hits	344	Shared Neighborhood Hits	260
SwissProt Accessions	Q6MZW2, Q8TBU0, Q9UPU1	Gene names	FSTL4, KIAA1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4).

LU_HUMAN
NC score	0.315323 (rank : 932)	θ value	0.00102713 (rank : 918)
Query Neighborhood Hits	1959	Target Neighborhood Hits	283	Shared Neighborhood Hits	232
SwissProt Accessions	P50895, Q86VC7	Gene names	BCAM, LU, MSK19
Domain Architecture
Description	Lutheran blood group glycoprotein precursor (B-CAM cell surface glycoprotein) (Auberger B antigen) (F8/G253 antigen) (CD239 antigen).

RN5A_MOUSE
NC score	0.313898 (rank : 933)	θ value	0.279714 (rank : 1194)
Query Neighborhood Hits	1959	Target Neighborhood Hits	899	Shared Neighborhood Hits	617
SwissProt Accessions	Q05921, Q9ERU7	Gene names	Rnasel, Rns4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

CD22_MOUSE
NC score	0.312405 (rank : 934)	θ value	1.29631e-06 (rank : 743)
Query Neighborhood Hits	1959	Target Neighborhood Hits	331	Shared Neighborhood Hits	233
SwissProt Accessions	P35329, Q9JHL2, Q9JJX9, Q9JJY0, Q9JJY1, Q9R056, Q9R094, Q9WU51	Gene names	Cd22, Lyb-8
Domain Architecture
Description	B-cell receptor CD22 precursor (Leu-14) (B-lymphocyte cell adhesion molecule) (BL-CAM) (Siglec-2).

KIRR2_MOUSE
NC score	0.312117 (rank : 935)	θ value	2.21117e-06 (rank : 758)
Query Neighborhood Hits	1959	Target Neighborhood Hits	326	Shared Neighborhood Hits	238
SwissProt Accessions	Q7TSU7, Q7TQ98	Gene names	Kirrel2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2).

CD22_HUMAN
NC score	0.311952 (rank : 936)	θ value	8.11959e-09 (rank : 617)
Query Neighborhood Hits	1959	Target Neighborhood Hits	365	Shared Neighborhood Hits	246
SwissProt Accessions	P20273, O95699, O95701, O95702, O95703, Q01665, Q92872, Q92873, Q9UQA6, Q9UQA7, Q9UQA8, Q9UQA9, Q9UQB0, Q9Y2A6	Gene names	CD22
Domain Architecture
Description	B-cell receptor CD22 precursor (Leu-14) (B-lymphocyte cell adhesion molecule) (BL-CAM) (Siglec-2).

TMIGD_MOUSE
NC score	0.310433 (rank : 937)	θ value	0.00390308 (rank : 971)
Query Neighborhood Hits	1959	Target Neighborhood Hits	234	Shared Neighborhood Hits	214
SwissProt Accessions	Q9D7L8, Q8R202	Gene names	Tmigd
Domain Architecture	No domain graphic available
Description	Transmembrane and immunoglobulin domain-containing protein precursor.

FSTL5_HUMAN
NC score	0.310431 (rank : 938)	θ value	0.000270298 (rank : 873)
Query Neighborhood Hits	1959	Target Neighborhood Hits	347	Shared Neighborhood Hits	258
SwissProt Accessions	Q8N475, Q9NSW7, Q9ULF7	Gene names	FSTL5, KIAA1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5).

FSTL4_MOUSE
NC score	0.309889 (rank : 939)	θ value	5.44631e-05 (rank : 825)
Query Neighborhood Hits	1959	Target Neighborhood Hits	333	Shared Neighborhood Hits	255
SwissProt Accessions	Q5STE3, Q5DU03	Gene names	Fstl4, Kiaa1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4) (m- D/Bsp120I 1-1).

RAGE_MOUSE
NC score	0.308866 (rank : 940)	θ value	3.77169e-06 (rank : 768)
Query Neighborhood Hits	1959	Target Neighborhood Hits	295	Shared Neighborhood Hits	220
SwissProt Accessions	Q62151	Gene names	Ager, Rage
Domain Architecture
Description	Advanced glycosylation end product-specific receptor precursor (Receptor for advanced glycosylation end products).

FSTL5_MOUSE
NC score	0.305883 (rank : 941)	θ value	0.00035302 (rank : 878)
Query Neighborhood Hits	1959	Target Neighborhood Hits	355	Shared Neighborhood Hits	255
SwissProt Accessions	Q8BFR2, Q80TG3, Q8C4T3	Gene names	Fstl5, Kiaa1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5) (m- D/Bsp120I 1-2).

MALT1_HUMAN
NC score	0.305434 (rank : 942)	θ value	1.06291 (rank : 1389)
Query Neighborhood Hits	1959	Target Neighborhood Hits	236	Shared Neighborhood Hits	208
SwissProt Accessions	Q9UDY8, Q9NTB7, Q9ULX4	Gene names	MALT1, MLT
Domain Architecture
Description	Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (EC 3.4.22.-) (MALT lymphoma-associated translocation) (Paracaspase).

KIRR3_HUMAN
NC score	0.300046 (rank : 943)	θ value	2.61198e-07 (rank : 699)
Query Neighborhood Hits	1959	Target Neighborhood Hits	302	Shared Neighborhood Hits	232
SwissProt Accessions	Q8IZU9, Q6UWJ9, Q6UWL5, Q96JG0	Gene names	KIRREL3, KIAA1867, NEPH2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 3 precursor (Kin of irregular chiasm-like protein 3) (Nephrin-like 2).

ICAM5_MOUSE
NC score	0.299903 (rank : 944)	θ value	0.000270298 (rank : 874)
Query Neighborhood Hits	1959	Target Neighborhood Hits	308	Shared Neighborhood Hits	241
SwissProt Accessions	Q60625	Gene names	Icam5, Tlcn
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

NPTN_HUMAN
NC score	0.299495 (rank : 945)	θ value	0.0252991 (rank : 1030)
Query Neighborhood Hits	1959	Target Neighborhood Hits	212	Shared Neighborhood Hits	197
SwissProt Accessions	Q9Y639, Q59EJ9, Q6NVX7, Q9Y640	Gene names	NPTN, SDFR1, SDR1
Domain Architecture	No domain graphic available
Description	Neuroplastin precursor (Stromal cell-derived receptor 1) (SDR-1).

NPTN_MOUSE
NC score	0.298410 (rank : 946)	θ value	0.0330416 (rank : 1042)
Query Neighborhood Hits	1959	Target Neighborhood Hits	216	Shared Neighborhood Hits	197
SwissProt Accessions	P97300, Q3U519, Q8C637, Q8C6H8	Gene names	Nptn, Sdfr1, Sdr1
Domain Architecture	No domain graphic available
Description	Neuroplastin precursor (Stromal cell-derived receptor 1) (SDR-1).

KIRR3_MOUSE
NC score	0.298332 (rank : 947)	θ value	1.99992e-07 (rank : 691)
Query Neighborhood Hits	1959	Target Neighborhood Hits	292	Shared Neighborhood Hits	226
SwissProt Accessions	Q8BR86, Q6P555, Q810H3, Q8BGQ5, Q8BRS8	Gene names	Kirrel3, Kiaa1867
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 3 precursor (Kin of irregular chiasm-like protein 3).

KIRR1_HUMAN
NC score	0.293934 (rank : 948)	θ value	0.00228821 (rank : 944)
Query Neighborhood Hits	1959	Target Neighborhood Hits	401	Shared Neighborhood Hits	248
SwissProt Accessions	Q96J84, Q5XKC6, Q7Z696, Q7Z7N8, Q8TB15, Q9H9N1, Q9NVA5	Gene names	KIRREL, NEPH1
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 1 precursor (Kin of irregular chiasm-like protein 1) (Nephrin-like protein 1).

ICAM5_HUMAN
NC score	0.290820 (rank : 949)	θ value	0.000121331 (rank : 846)
Query Neighborhood Hits	1959	Target Neighborhood Hits	276	Shared Neighborhood Hits	232
SwissProt Accessions	Q9UMF0, Q9Y6F3	Gene names	ICAM5, TLCN, TLN
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

JAM3_HUMAN
NC score	0.290752 (rank : 950)	θ value	0.00228821 (rank : 943)
Query Neighborhood Hits	1959	Target Neighborhood Hits	271	Shared Neighborhood Hits	226
SwissProt Accessions	Q9BX67, Q8WWL8, Q96FL1	Gene names	JAM3
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule C precursor (JAM-C) (Junctional adhesion molecule 3) (JAM-3) (JAM-2).

HMCN1_HUMAN
NC score	0.290390 (rank : 951)	θ value	1.32601e-43 (rank : 14)
Query Neighborhood Hits	1959	Target Neighborhood Hits	983	Shared Neighborhood Hits	342
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

KIRR1_MOUSE
NC score	0.290068 (rank : 952)	θ value	0.00228821 (rank : 945)
Query Neighborhood Hits	1959	Target Neighborhood Hits	403	Shared Neighborhood Hits	245
SwissProt Accessions	Q80W68, Q8CIJ4, Q8CJ59, Q923L4	Gene names	Kirrel1, Kirrel, Neph1
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 1 precursor (Kin of irregular chiasm-like protein 1) (Nephrin-like protein 1).

JAM3_MOUSE
NC score	0.289814 (rank : 953)	θ value	0.00665767 (rank : 982)
Query Neighborhood Hits	1959	Target Neighborhood Hits	286	Shared Neighborhood Hits	228
SwissProt Accessions	Q9D8B7, Q8BT59, Q9D1M9, Q9EPK4	Gene names	Jam3
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule C precursor (JAM-C) (Junctional adhesion molecule 3) (JAM-3) (JAM-2).

STK31_MOUSE
NC score	0.289649 (rank : 954)	θ value	5.27518 (rank : 1786)
Query Neighborhood Hits	1959	Target Neighborhood Hits	474	Shared Neighborhood Hits	309
SwissProt Accessions	Q99MW1	Gene names	Stk31
Domain Architecture
Description	Serine/threonine-protein kinase 31 (EC 2.7.11.1).

PGBM_HUMAN
NC score	0.289355 (rank : 955)	θ value	2.67802e-36 (rank : 21)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1113	Shared Neighborhood Hits	376
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

MUC18_MOUSE
NC score	0.288606 (rank : 956)	θ value	0.000158464 (rank : 858)
Query Neighborhood Hits	1959	Target Neighborhood Hits	292	Shared Neighborhood Hits	221
SwissProt Accessions	Q8R2Y2, Q9EPF1, Q9ESS7, Q9JHQ2, Q9JHQ3	Gene names	Mcam, Muc18
Domain Architecture	No domain graphic available
Description	Cell surface glycoprotein MUC18 precursor (Melanoma-associated antigen MUC18) (Melanoma cell adhesion molecule) (Gicerin).

MUC18_HUMAN
NC score	0.288312 (rank : 957)	θ value	0.365318 (rank : 1226)
Query Neighborhood Hits	1959	Target Neighborhood Hits	275	Shared Neighborhood Hits	221
SwissProt Accessions	P43121, O95812, Q59E86, Q6PHR3, Q6ZTR2	Gene names	MCAM, MUC18
Domain Architecture
Description	Cell surface glycoprotein MUC18 precursor (Melanoma-associated antigen MUC18) (Melanoma cell adhesion molecule) (Melanoma-associated antigen A32) (S-endo 1 endothelial-associated antigen) (Cell surface glycoprotein P1H12) (CD146 antigen).

JAM1_HUMAN
NC score	0.288019 (rank : 958)	θ value	1.06291 (rank : 1384)
Query Neighborhood Hits	1959	Target Neighborhood Hits	294	Shared Neighborhood Hits	234
SwissProt Accessions	Q9Y624	Gene names	F11R, JAM1, JCAM
Domain Architecture
Description	Junctional adhesion molecule A precursor (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (Platelet adhesion molecule 1) (PAM-1) (Platelet F11 receptor) (CD321 antigen).

JAM2_HUMAN
NC score	0.284369 (rank : 959)	θ value	0.000121331 (rank : 848)
Query Neighborhood Hits	1959	Target Neighborhood Hits	304	Shared Neighborhood Hits	246
SwissProt Accessions	P57087, Q6UXG6, Q6YNC1	Gene names	JAM2, C21orf43, VEJAM
Domain Architecture
Description	Junctional adhesion molecule B precursor (JAM-B) (Junctional adhesion molecule 2) (Vascular endothelial junction-associated molecule) (VE- JAM) (CD322 antigen).

LRIG1_HUMAN
NC score	0.283999 (rank : 960)	θ value	9.56915e-18 (rank : 236)
Query Neighborhood Hits	1959	Target Neighborhood Hits	654	Shared Neighborhood Hits	309
SwissProt Accessions	Q96JA1, Q6IQ51, Q96CF9, Q9BYB8, Q9UFI4	Gene names	LRIG1, LIG1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

PTPRD_MOUSE
NC score	0.283059 (rank : 961)	θ value	6.85773e-16 (rank : 327)
Query Neighborhood Hits	1959	Target Neighborhood Hits	491	Shared Neighborhood Hits	320
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

KAZD1_MOUSE
NC score	0.282842 (rank : 962)	θ value	0.000270298 (rank : 875)
Query Neighborhood Hits	1959	Target Neighborhood Hits	281	Shared Neighborhood Hits	201
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).

PTPRF_HUMAN
NC score	0.282838 (rank : 963)	θ value	5.25075e-16 (rank : 319)
Query Neighborhood Hits	1959	Target Neighborhood Hits	489	Shared Neighborhood Hits	322
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

SIG11_HUMAN
NC score	0.281900 (rank : 964)	θ value	9.92553e-07 (rank : 738)
Query Neighborhood Hits	1959	Target Neighborhood Hits	273	Shared Neighborhood Hits	241
SwissProt Accessions	Q96RL6	Gene names	SIGLEC11
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 11 precursor (Siglec-11) (Sialic acid-binding lectin 11).

LRIG2_HUMAN
NC score	0.281429 (rank : 965)	θ value	3.40345e-15 (rank : 359)
Query Neighborhood Hits	1959	Target Neighborhood Hits	595	Shared Neighborhood Hits	296
SwissProt Accessions	O94898, Q9NSN2	Gene names	LRIG2, KIAA0806, LIG2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor (LIG-2).

CI094_HUMAN
NC score	0.280328 (rank : 966)	θ value	2.36244e-08 (rank : 642)
Query Neighborhood Hits	1959	Target Neighborhood Hits	310	Shared Neighborhood Hits	232
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

LRIG2_MOUSE
NC score	0.280189 (rank : 967)	θ value	5.25075e-16 (rank : 316)
Query Neighborhood Hits	1959	Target Neighborhood Hits	586	Shared Neighborhood Hits	292
SwissProt Accessions	Q52KR2, Q69ZY8	Gene names	Lrig2, Kiaa0806
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor.

PGBM_MOUSE
NC score	0.279851 (rank : 968)	θ value	9.54697e-26 (rank : 76)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1073	Shared Neighborhood Hits	354
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

JAM1_MOUSE
NC score	0.278816 (rank : 969)	θ value	3.0926 (rank : 1593)
Query Neighborhood Hits	1959	Target Neighborhood Hits	287	Shared Neighborhood Hits	221
SwissProt Accessions	O88792	Gene names	F11r, Jam1, Jcam, Jcam1
Domain Architecture
Description	Junctional adhesion molecule A precursor (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (CD321 antigen).

IGS4B_MOUSE
NC score	0.278283 (rank : 970)	θ value	5.44631e-05 (rank : 826)
Query Neighborhood Hits	1959	Target Neighborhood Hits	328	Shared Neighborhood Hits	235
SwissProt Accessions	Q99N28, Q8BSQ8, Q8K1H8	Gene names	Igsf4b, Necl1, Syncam3, Tsll1
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 4B precursor (Nectin-like protein 1) (Necl-1) (TSLC1-like protein 1) (Synaptic cell adhesion molecule 3).

LRIG1_MOUSE
NC score	0.278108 (rank : 971)	θ value	1.99529e-15 (rank : 346)
Query Neighborhood Hits	1959	Target Neighborhood Hits	627	Shared Neighborhood Hits	297
SwissProt Accessions	P70193	Gene names	Lrig1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

PTPRD_HUMAN
NC score	0.277612 (rank : 972)	θ value	3.63628e-17 (rank : 268)
Query Neighborhood Hits	1959	Target Neighborhood Hits	485	Shared Neighborhood Hits	314
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

SIG10_HUMAN
NC score	0.277541 (rank : 973)	θ value	2.44474e-05 (rank : 806)
Query Neighborhood Hits	1959	Target Neighborhood Hits	363	Shared Neighborhood Hits	276
SwissProt Accessions	Q96LC7, Q6UXI8, Q96G54, Q96LC8	Gene names	SIGLEC10, SLG2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 10 precursor (Siglec-10) (Siglec- like protein 2).

VRK3_HUMAN
NC score	0.276386 (rank : 974)	θ value	θ > 10 (rank : 2118)
Query Neighborhood Hits	1959	Target Neighborhood Hits	349	Shared Neighborhood Hits	326
SwissProt Accessions	Q8IV63, Q9P2V8	Gene names	VRK3
Domain Architecture
Description	Serine/threonine-protein kinase VRK3 (EC 2.7.11.1) (Vaccinia-related kinase 3).

JAM2_MOUSE
NC score	0.275293 (rank : 975)	θ value	0.00134147 (rank : 923)
Query Neighborhood Hits	1959	Target Neighborhood Hits	292	Shared Neighborhood Hits	234
SwissProt Accessions	Q9JI59, Q8C5K9, Q8CE95	Gene names	Jam2, Vejam
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule B precursor (JAM-B) (Junctional adhesion molecule 2) (Vascular endothelial junction-associated molecule) (VE- JAM) (CD322 antigen).

VSIG2_HUMAN
NC score	0.274653 (rank : 976)	θ value	5.44631e-05 (rank : 832)
Query Neighborhood Hits	1959	Target Neighborhood Hits	321	Shared Neighborhood Hits	229
SwissProt Accessions	Q96IQ7, O95791, Q9NX42	Gene names	VSIG2, CTH, CTXL
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 2 precursor (CT- like protein) (Cortical thymocyte-like protein).

PTPRS_HUMAN
NC score	0.274332 (rank : 977)	θ value	3.89403e-11 (rank : 540)
Query Neighborhood Hits	1959	Target Neighborhood Hits	472	Shared Neighborhood Hits	316
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

IGS4B_HUMAN
NC score	0.270183 (rank : 978)	θ value	0.00298849 (rank : 953)
Query Neighborhood Hits	1959	Target Neighborhood Hits	305	Shared Neighborhood Hits	227
SwissProt Accessions	Q8N126, Q9NVJ5, Q9UJP1	Gene names	IGSF4B, NECL1, SYNCAM3, TSLL1
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 4B precursor (Nectin-like protein 1) (TSLC1-like protein 1) (Synaptic cell adhesion molecule 3) (Brain immunoglobulin receptor).

LRIG3_MOUSE
NC score	0.269277 (rank : 979)	θ value	1.68911e-14 (rank : 400)
Query Neighborhood Hits	1959	Target Neighborhood Hits	611	Shared Neighborhood Hits	296
SwissProt Accessions	Q6P1C6, Q6ZPE6, Q8BRF0, Q8BS51, Q8C5E4	Gene names	Lrig3, Kiaa3016
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor.

MFA3L_HUMAN
NC score	0.269228 (rank : 980)	θ value	0.0148317 (rank : 1010)
Query Neighborhood Hits	1959	Target Neighborhood Hits	230	Shared Neighborhood Hits	209
SwissProt Accessions	O75121, Q6TNA8, Q9BVE1, Q9BXK0	Gene names	MFAP3L, KIAA0626
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 3-like precursor (Protein kinase NYD-SP9).

CEAM5_HUMAN
NC score	0.268564 (rank : 981)	θ value	0.00869519 (rank : 993)
Query Neighborhood Hits	1959	Target Neighborhood Hits	343	Shared Neighborhood Hits	252
SwissProt Accessions	P06731	Gene names	CEACAM5, CEA
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 5 precursor (Carcinoembryonic antigen) (CEA) (Meconium antigen 100) (CD66e antigen).

LRIG3_HUMAN
NC score	0.266406 (rank : 982)	θ value	1.29331e-14 (rank : 391)
Query Neighborhood Hits	1959	Target Neighborhood Hits	601	Shared Neighborhood Hits	295
SwissProt Accessions	Q6UXM1, Q6UXL7, Q8NC72	Gene names	LRIG3, LIG3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor (LIG-3).

BASI_HUMAN
NC score	0.264588 (rank : 983)	θ value	0.0961366 (rank : 1102)
Query Neighborhood Hits	1959	Target Neighborhood Hits	211	Shared Neighborhood Hits	188
SwissProt Accessions	P35613, Q7Z796, Q8IZL7	Gene names	BSG
Domain Architecture
Description	Basigin precursor (Leukocyte activation antigen M6) (Collagenase stimulatory factor) (Extracellular matrix metalloproteinase inducer) (EMMPRIN) (5F7) (Tumor cell-derived collagenase stimulatory factor) (TCSF) (OK blood group antigen) (CD147 antigen).

VSIG2_MOUSE
NC score	0.264318 (rank : 984)	θ value	0.00665767 (rank : 989)
Query Neighborhood Hits	1959	Target Neighborhood Hits	316	Shared Neighborhood Hits	217
SwissProt Accessions	Q9Z109, Q9CVA4, Q9D0T4	Gene names	Vsig2, Ctm, Ctxl
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 2 precursor (CT- like protein) (Cortical thymocyte-like protein).

K2002_MOUSE
NC score	0.264036 (rank : 985)	θ value	8.99809 (rank : 1912)
Query Neighborhood Hits	1959	Target Neighborhood Hits	267	Shared Neighborhood Hits	232
SwissProt Accessions	Q69Z38, Q8R365	Gene names	Kiaa2002
Domain Architecture	No domain graphic available
Description	Uncharacterized tyrosine-protein kinase KIAA2002 (EC 2.7.10.2).

CEA20_HUMAN
NC score	0.263268 (rank : 986)	θ value	0.00665767 (rank : 979)
Query Neighborhood Hits	1959	Target Neighborhood Hits	251	Shared Neighborhood Hits	197
SwissProt Accessions	Q6UY09	Gene names	CEACAM20
Domain Architecture	No domain graphic available
Description	Carcinoembryonic antigen-related cell adhesion molecule 20 precursor.

CEAM1_MOUSE
NC score	0.258273 (rank : 987)	θ value	1.06291 (rank : 1365)
Query Neighborhood Hits	1959	Target Neighborhood Hits	326	Shared Neighborhood Hits	245
SwissProt Accessions	P31809	Gene names	Ceacam1, Bgp, Bgp1, Bgpd
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 1 precursor (Biliary glycoprotein 1) (BGP-1) (Murine hepatitis virus receptor) (MHV-R) (Biliary glycoprotein D).

NRG2_HUMAN
NC score	0.256482 (rank : 988)	θ value	0.00869519 (rank : 995)
Query Neighborhood Hits	1959	Target Neighborhood Hits	419	Shared Neighborhood Hits	258
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

KAZD1_HUMAN
NC score	0.256338 (rank : 989)	θ value	0.0330416 (rank : 1036)
Query Neighborhood Hits	1959	Target Neighborhood Hits	248	Shared Neighborhood Hits	165
SwissProt Accessions	Q96I82, Q6ZMB1, Q9BQ73	Gene names	KAZALD1
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor.

BASI_MOUSE
NC score	0.256332 (rank : 990)	θ value	0.365318 (rank : 1203)
Query Neighborhood Hits	1959	Target Neighborhood Hits	238	Shared Neighborhood Hits	201
SwissProt Accessions	P18572, Q6LDB0, Q7TSC0	Gene names	Bsg
Domain Architecture
Description	Basigin precursor (Basic immunoglobulin superfamily) (Membrane glycoprotein gp42) (HT7 antigen) (CD147 antigen).

NTKL_HUMAN
NC score	0.255430 (rank : 991)	θ value	θ > 10 (rank : 2056)
Query Neighborhood Hits	1959	Target Neighborhood Hits	266	Shared Neighborhood Hits	223
SwissProt Accessions	Q96KG9, Q96G50, Q96KG8, Q96KH1, Q9HAW5, Q9HBL3, Q9NR53	Gene names	SCYL1, GKLP, NTKL, TAPK, TEIF, TRAP
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like protein (SCY1-like protein 1) (Teratoma- associated tyrosine kinase) (Telomerase transcriptional element- interacting factor) (Telomerase regulation-associated protein).

VRK3_MOUSE
NC score	0.249058 (rank : 992)	θ value	θ > 10 (rank : 2119)
Query Neighborhood Hits	1959	Target Neighborhood Hits	342	Shared Neighborhood Hits	322
SwissProt Accessions	Q8K3G5, Q921W6	Gene names	Vrk3
Domain Architecture
Description	Serine/threonine-protein kinase VRK3 (EC 2.7.11.1) (Vaccinia-related kinase 3).

NRG2_MOUSE
NC score	0.248330 (rank : 993)	θ value	0.0193708 (rank : 1020)
Query Neighborhood Hits	1959	Target Neighborhood Hits	392	Shared Neighborhood Hits	239
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

IBP7_HUMAN
NC score	0.246637 (rank : 994)	θ value	0.00102713 (rank : 916)
Query Neighborhood Hits	1959	Target Neighborhood Hits	220	Shared Neighborhood Hits	165
SwissProt Accessions	Q16270, Q07822	Gene names	IGFBP7, MAC25, PSF
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein) (Prostacyclin-stimulating factor) (PGI2-stimulating factor) (IGFBP-rP1).

FCRL5_HUMAN
NC score	0.243957 (rank : 995)	θ value	θ > 10 (rank : 2012)
Query Neighborhood Hits	1959	Target Neighborhood Hits	267	Shared Neighborhood Hits	214
SwissProt Accessions	Q96RD9, Q495Q2, Q495Q4, Q5VYK9, Q6UY46	Gene names	FCRL5, FCRH5, IRTA2
Domain Architecture	No domain graphic available
Description	Fc receptor-like protein 5 precursor (Immunoglobulin receptor translocation-associated gene 2 protein) (BXMAS1) (CD307 antigen).

CEAM1_HUMAN
NC score	0.239004 (rank : 996)	θ value	0.00228821 (rank : 940)
Query Neighborhood Hits	1959	Target Neighborhood Hits	348	Shared Neighborhood Hits	237
SwissProt Accessions	P13688, O60430, Q13858, Q15600, Q9UQV9	Gene names	CEACAM1, BGP, BGP1
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 1 precursor (Biliary glycoprotein 1) (BGP-1) (CD66 antigen) (CD66a antigen).

IBP7_MOUSE
NC score	0.236118 (rank : 997)	θ value	0.0252991 (rank : 1029)
Query Neighborhood Hits	1959	Target Neighborhood Hits	230	Shared Neighborhood Hits	161
SwissProt Accessions	Q61581, O88812, Q9EQW0	Gene names	Igfbp7, Mac25
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).

FNDC3_MOUSE
NC score	0.234870 (rank : 998)	θ value	0.813845 (rank : 1325)
Query Neighborhood Hits	1959	Target Neighborhood Hits	207	Shared Neighborhood Hits	133
SwissProt Accessions	Q8BX90, Q2VEY7, Q6ZQ15, Q811D3, Q8BTM3	Gene names	Fndc3a, D14Ertd453e, Fndc3, Kiaa0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

FNDC3_HUMAN
NC score	0.234008 (rank : 999)	θ value	0.813845 (rank : 1324)
Query Neighborhood Hits	1959	Target Neighborhood Hits	196	Shared Neighborhood Hits	133
SwissProt Accessions	Q9Y2H6, Q5JVF9, Q6EVH3, Q6N020, Q6P9D5, Q9H1W1	Gene names	FNDC3A, FNDC3, KIAA0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

FCRL2_HUMAN
NC score	0.233449 (rank : 1000)	θ value	θ > 10 (rank : 2011)
Query Neighborhood Hits	1959	Target Neighborhood Hits	251	Shared Neighborhood Hits	189
SwissProt Accessions	Q96LA5, Q6NTA1, Q9BZI4, Q9BZI5, Q9BZI6	Gene names	FCRL2, FCRH2, IFGP4, IRTA4, SPAP1
Domain Architecture	No domain graphic available
Description	Fc receptor-like protein 2 precursor (SH2 domain-containing phosphatase anchor protein 1) (Fc receptor homolog 2) (FcRH2) (Immunoglobulin receptor translocation-associated 4 protein).

VSIG4_HUMAN
NC score	0.232804 (rank : 1001)	θ value	3.0926 (rank : 1627)
Query Neighborhood Hits	1959	Target Neighborhood Hits	236	Shared Neighborhood Hits	188
SwissProt Accessions	Q9Y279, Q6UXI4	Gene names	VSIG4, Z39IG
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 4 precursor (Protein Z39Ig).

MFA3L_MOUSE
NC score	0.228006 (rank : 1002)	θ value	0.365318 (rank : 1223)
Query Neighborhood Hits	1959	Target Neighborhood Hits	214	Shared Neighborhood Hits	196
SwissProt Accessions	Q9D3X9, Q80TV6, Q8BJA9	Gene names	Mfap3l, Kiaa0626
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 3-like precursor.

CD166_MOUSE
NC score	0.225316 (rank : 1003)	θ value	0.813845 (rank : 1315)
Query Neighborhood Hits	1959	Target Neighborhood Hits	252	Shared Neighborhood Hits	188
SwissProt Accessions	Q61490, O70136, Q8CDA5, Q8R2T0	Gene names	Alcam
Domain Architecture
Description	CD166 antigen precursor (Activated leukocyte-cell adhesion molecule) (ALCAM) (DM-GRASP protein).

GPA33_MOUSE
NC score	0.221924 (rank : 1004)	θ value	0.0431538 (rank : 1058)
Query Neighborhood Hits	1959	Target Neighborhood Hits	294	Shared Neighborhood Hits	183
SwissProt Accessions	Q9JKA5, Q922D5	Gene names	Gpa33
Domain Architecture
Description	Cell surface A33 antigen precursor (Glycoprotein A33) (mA33).

SIGL5_MOUSE
NC score	0.221023 (rank : 1005)	θ value	0.0563607 (rank : 1080)
Query Neighborhood Hits	1959	Target Neighborhood Hits	271	Shared Neighborhood Hits	223
SwissProt Accessions	Q920G3	Gene names	Siglec5, Siglecf
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 5 precursor (Siglec-5) (Sialic acid-binding Ig-like lectin-F) (mSiglec-F).

ATL3_HUMAN
NC score	0.214609 (rank : 1006)	θ value	1.69304e-06 (rank : 751)
Query Neighborhood Hits	1959	Target Neighborhood Hits	414	Shared Neighborhood Hits	263
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

CD166_HUMAN
NC score	0.210631 (rank : 1007)	θ value	4.03905 (rank : 1642)
Query Neighborhood Hits	1959	Target Neighborhood Hits	247	Shared Neighborhood Hits	183
SwissProt Accessions	Q13740, O60892	Gene names	ALCAM, MEMD
Domain Architecture
Description	CD166 antigen precursor (Activated leukocyte-cell adhesion molecule) (ALCAM).

GPA33_HUMAN
NC score	0.208884 (rank : 1008)	θ value	0.279714 (rank : 1180)
Query Neighborhood Hits	1959	Target Neighborhood Hits	273	Shared Neighborhood Hits	182
SwissProt Accessions	Q99795	Gene names	GPA33
Domain Architecture
Description	Cell surface A33 antigen precursor (Glycoprotein A33).

CEAM6_HUMAN
NC score	0.202237 (rank : 1009)	θ value	4.03905 (rank : 1644)
Query Neighborhood Hits	1959	Target Neighborhood Hits	308	Shared Neighborhood Hits	229
SwissProt Accessions	P40199, Q14920	Gene names	CEACAM6, NCA
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 6 precursor (Normal cross-reacting antigen) (Nonspecific crossreacting antigen) (CD66c antigen).

ESAM_HUMAN
NC score	0.197858 (rank : 1010)	θ value	0.125558 (rank : 1121)
Query Neighborhood Hits	1959	Target Neighborhood Hits	251	Shared Neighborhood Hits	195
SwissProt Accessions	Q96AP7, Q96T50	Gene names	ESAM
Domain Architecture	No domain graphic available
Description	Endothelial cell-selective adhesion molecule precursor.

NRG1_HUMAN
NC score	0.193000 (rank : 1011)	θ value	0.0431538 (rank : 1061)
Query Neighborhood Hits	1959	Target Neighborhood Hits	285	Shared Neighborhood Hits	170
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

SIGL8_HUMAN
NC score	0.192024 (rank : 1012)	θ value	9.29e-05 (rank : 841)
Query Neighborhood Hits	1959	Target Neighborhood Hits	252	Shared Neighborhood Hits	216
SwissProt Accessions	Q9NYZ4, Q7Z728	Gene names	SIGLEC8, SAF2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 8 precursor (Siglec-8) (Sialoadhesin family member 2) (SAF-2) (CDw329 antigen).

SIGL5_HUMAN
NC score	0.191847 (rank : 1013)	θ value	0.00035302 (rank : 879)
Query Neighborhood Hits	1959	Target Neighborhood Hits	246	Shared Neighborhood Hits	193
SwissProt Accessions	O15389	Gene names	SIGLEC5, CD33L2, OBBP2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 5 precursor (Siglec-5) (Obesity- binding protein 2) (OB-binding protein 2) (OB-BP2) (CD33 antigen-like 2) (CD170 antigen).

LRFN4_HUMAN
NC score	0.191644 (rank : 1014)	θ value	0.00020696 (rank : 864)
Query Neighborhood Hits	1959	Target Neighborhood Hits	462	Shared Neighborhood Hits	222
SwissProt Accessions	Q6PJG9, Q9BWJ0	Gene names	LRFN4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursor.

LRFN4_MOUSE
NC score	0.190138 (rank : 1015)	θ value	5.44631e-05 (rank : 827)
Query Neighborhood Hits	1959	Target Neighborhood Hits	442	Shared Neighborhood Hits	213
SwissProt Accessions	Q80XU8, Q3TQG8, Q8K3C4	Gene names	Lrfn4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursor.

LRFN2_HUMAN
NC score	0.188505 (rank : 1016)	θ value	0.000786445 (rank : 907)
Query Neighborhood Hits	1959	Target Neighborhood Hits	450	Shared Neighborhood Hits	220
SwissProt Accessions	Q9ULH4, Q5SYP9	Gene names	LRFN2, KIAA1246
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 2 precursor.

LRFN2_MOUSE
NC score	0.188237 (rank : 1017)	θ value	0.000786445 (rank : 908)
Query Neighborhood Hits	1959	Target Neighborhood Hits	450	Shared Neighborhood Hits	220
SwissProt Accessions	Q80TG9, Q9CYK3	Gene names	Lrfn2, Kiaa1246
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 2 precursor.

LRFN3_MOUSE
NC score	0.186811 (rank : 1018)	θ value	7.1131e-05 (rank : 835)
Query Neighborhood Hits	1959	Target Neighborhood Hits	455	Shared Neighborhood Hits	220
SwissProt Accessions	Q8BLY3	Gene names	Lrfn3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 3 precursor.

CILP2_HUMAN
NC score	0.185640 (rank : 1019)	θ value	0.00228821 (rank : 941)
Query Neighborhood Hits	1959	Target Neighborhood Hits	307	Shared Neighborhood Hits	190
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

IL1R2_HUMAN
NC score	0.180444 (rank : 1020)	θ value	θ > 10 (rank : 2034)
Query Neighborhood Hits	1959	Target Neighborhood Hits	153	Shared Neighborhood Hits	125
SwissProt Accessions	P27930, Q9UE68	Gene names	IL1R2, IL1RB
Domain Architecture
Description	Interleukin-1 receptor type II precursor (IL-1R-2) (IL-1R-beta) (CD121b antigen) (CDw121b).

SIG12_HUMAN
NC score	0.179689 (rank : 1021)	θ value	0.000786445 (rank : 911)
Query Neighborhood Hits	1959	Target Neighborhood Hits	245	Shared Neighborhood Hits	213
SwissProt Accessions	Q96PQ1, Q8IYH7	Gene names	SIGLEC12, SIGLECL1, SLG
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 12 precursor (Siglec-12) (Sialic acid-binding Ig-like lectin-like 1) (Siglec-L1).

LRFN3_HUMAN
NC score	0.179472 (rank : 1022)	θ value	4.1701e-05 (rank : 815)
Query Neighborhood Hits	1959	Target Neighborhood Hits	444	Shared Neighborhood Hits	211
SwissProt Accessions	Q9BTN0, Q6UY10	Gene names	LRFN3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 3 precursor.

ESAM_MOUSE
NC score	0.178966 (rank : 1023)	θ value	0.125558 (rank : 1122)
Query Neighborhood Hits	1959	Target Neighborhood Hits	222	Shared Neighborhood Hits	173
SwissProt Accessions	Q925F2	Gene names	Esam, Esam1
Domain Architecture	No domain graphic available
Description	Endothelial cell-selective adhesion molecule precursor.

CEAM8_HUMAN
NC score	0.178086 (rank : 1024)	θ value	θ > 10 (rank : 1981)
Query Neighborhood Hits	1959	Target Neighborhood Hits	264	Shared Neighborhood Hits	212
SwissProt Accessions	P31997, O60399, Q16574	Gene names	CEACAM8, CGM6
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 8 precursor (Carcinoembryonic antigen CGM6) (Nonspecific cross-reacting antigen NCA-95) (CD67 antigen) (CD66b antigen).

LRC21_MOUSE
NC score	0.176160 (rank : 1025)	θ value	0.00134147 (rank : 926)
Query Neighborhood Hits	1959	Target Neighborhood Hits	462	Shared Neighborhood Hits	229
SwissProt Accessions	Q8K099, Q8BXN3	Gene names	Lrrc21, Pal
Domain Architecture
Description	Leucine-rich repeat-containing protein 21 precursor (Photoreceptor- associated LRR superfamily protein) (Retina-specific protein PAL).

LRFN5_MOUSE
NC score	0.176106 (rank : 1026)	θ value	0.00020696 (rank : 865)
Query Neighborhood Hits	1959	Target Neighborhood Hits	472	Shared Neighborhood Hits	227
SwissProt Accessions	Q8BXA0, Q8BJH4, Q8BZL0	Gene names	Lrfn5
Domain Architecture
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 5 precursor.

LRC21_HUMAN
NC score	0.175531 (rank : 1027)	θ value	0.00102713 (rank : 917)
Query Neighborhood Hits	1959	Target Neighborhood Hits	456	Shared Neighborhood Hits	224
SwissProt Accessions	Q9P2V4, Q9Y4N7	Gene names	LRRC21, PAL
Domain Architecture
Description	Leucine-rich repeat-containing protein 21 precursor (Photoreceptor- associated LRR superfamily protein) (Retina-specific protein PAL).

PSG3_HUMAN
NC score	0.175530 (rank : 1028)	θ value	0.0431538 (rank : 1063)
Query Neighborhood Hits	1959	Target Neighborhood Hits	242	Shared Neighborhood Hits	196
SwissProt Accessions	Q16557, Q08265, Q9BRW2, Q9UPL4, Q9UQ77	Gene names	PSG3
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 3 precursor (PSBG-3) (Carcinoembryonic antigen SG5).

SIGL6_HUMAN
NC score	0.175501 (rank : 1029)	θ value	0.00390308 (rank : 965)
Query Neighborhood Hits	1959	Target Neighborhood Hits	233	Shared Neighborhood Hits	198
SwissProt Accessions	O43699, O15388, O43700	Gene names	SIGLEC6, CD33L, CD33L1, OBBP1
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 6 precursor (Siglec-6) (Obesity- binding protein 1) (OB-BP1) (CD33 antigen-like 1) (CDw327 antigen).

PSG8_HUMAN
NC score	0.175420 (rank : 1030)	θ value	0.21417 (rank : 1169)
Query Neighborhood Hits	1959	Target Neighborhood Hits	239	Shared Neighborhood Hits	194
SwissProt Accessions	Q9UQ74, O60410	Gene names	PSG8
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 8 precursor (PSBG-8).

PXK_MOUSE
NC score	0.172880 (rank : 1031)	θ value	1.38821 (rank : 1455)
Query Neighborhood Hits	1959	Target Neighborhood Hits	320	Shared Neighborhood Hits	226
SwissProt Accessions	Q8BX57, Q3TD60, Q3TEL7, Q3TZZ1, Q3U197, Q3U773, Q3UCS5, Q4FBH7, Q91WB6	Gene names	Pxk
Domain Architecture	No domain graphic available
Description	PX domain-containing protein kinase-like protein (Modulator of Na,K- ATPase) (MONaKA).

PSG4_HUMAN
NC score	0.172521 (rank : 1032)	θ value	0.813845 (rank : 1343)
Query Neighborhood Hits	1959	Target Neighborhood Hits	243	Shared Neighborhood Hits	196
SwissProt Accessions	Q00888, Q13047, Q13048, Q15234, Q15240, Q9UQ76	Gene names	PSG4, CGM4, PSG9
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 4 precursor (PSBG-4) (PSBG-9).

LRFN5_HUMAN
NC score	0.172332 (rank : 1033)	θ value	0.000461057 (rank : 885)
Query Neighborhood Hits	1959	Target Neighborhood Hits	464	Shared Neighborhood Hits	223
SwissProt Accessions	Q96NI6, Q86XL2	Gene names	LRFN5, C14orf146
Domain Architecture
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 5 precursor.

CXAR_HUMAN
NC score	0.167001 (rank : 1034)	θ value	2.36792 (rank : 1530)
Query Neighborhood Hits	1959	Target Neighborhood Hits	245	Shared Neighborhood Hits	167
SwissProt Accessions	P78310, O00694, Q8WWT6, Q8WWT7, Q8WWT8, Q9UKV4	Gene names	CXADR, CAR
Domain Architecture
Description	Coxsackievirus and adenovirus receptor precursor (Coxsackievirus B- adenovirus receptor) (hCAR) (CVB3-binding protein) (HCVADR).

PSG7_HUMAN
NC score	0.166483 (rank : 1035)	θ value	2.36792 (rank : 1558)
Query Neighborhood Hits	1959	Target Neighborhood Hits	239	Shared Neighborhood Hits	194
SwissProt Accessions	Q13046, Q15232	Gene names	PSG7
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 7 precursor (PSBG-7).

IRPL2_HUMAN
NC score	0.165890 (rank : 1036)	θ value	0.000461057 (rank : 882)
Query Neighborhood Hits	1959	Target Neighborhood Hits	194	Shared Neighborhood Hits	140
SwissProt Accessions	Q9NP60, Q9NZN0	Gene names	IL1RAPL2, IL1R9
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 2 precursor (IL1RAPL-2-related protein) (Interleukin-1 receptor 9) (IL-1R9) (IL-1 receptor accessory protein-like 2) (Three immunoglobulin domain- containing IL-1 receptor-related 1) (TIGIRR-1).

PSG11_HUMAN
NC score	0.164877 (rank : 1037)	θ value	1.81305 (rank : 1509)
Query Neighborhood Hits	1959	Target Neighborhood Hits	223	Shared Neighborhood Hits	191
SwissProt Accessions	Q9UQ72, Q13179, Q15242, Q9UNE4	Gene names	PSG11, PSG13
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 11 precursor (PSBG-11) (PSBG- 13).

PSG2_HUMAN
NC score	0.163591 (rank : 1038)	θ value	0.365318 (rank : 1229)
Query Neighborhood Hits	1959	Target Neighborhood Hits	229	Shared Neighborhood Hits	189
SwissProt Accessions	P11465, Q8TCD9, Q9UEA4, Q9UQ78	Gene names	PSG2
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 2 precursor (PSBG-2) (Pregnancy-specific beta-1 glycoprotein E) (PS-beta-E).

PSG1_HUMAN
NC score	0.163584 (rank : 1039)	θ value	1.38821 (rank : 1454)
Query Neighborhood Hits	1959	Target Neighborhood Hits	232	Shared Neighborhood Hits	195
SwissProt Accessions	P11464, O75236, P11462, P11463, Q15231, Q15241, Q15243, Q16660, Q9P1W5, Q9UQ79	Gene names	PSG1, B1G1, PSGGA
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 1 precursor (PSBG-1) (Pregnancy-specific beta-1 glycoprotein C/D) (PS-beta-C/D) (Fetal liver non-specific cross-reactive antigen 1/2) (FL-NCA-1/2) (PSG95) (CD66f antigen).

IRPL2_MOUSE
NC score	0.163579 (rank : 1040)	θ value	0.000461057 (rank : 883)
Query Neighborhood Hits	1959	Target Neighborhood Hits	195	Shared Neighborhood Hits	138
SwissProt Accessions	Q9ERS6, Q9ER66	Gene names	Il1rapl2
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 2 precursor (IL1RAPL-2-related protein) (TIGIRR-1).

IRPL1_MOUSE
NC score	0.162031 (rank : 1041)	θ value	0.00134147 (rank : 922)
Query Neighborhood Hits	1959	Target Neighborhood Hits	186	Shared Neighborhood Hits	149
SwissProt Accessions	P59823	Gene names	Il1rapl1
Domain Architecture	No domain graphic available
Description	X-linked interleukin-1 receptor accessory protein-like 1 precursor (IL1RAPL-1).

CILP1_MOUSE
NC score	0.160301 (rank : 1042)	θ value	0.0961366 (rank : 1104)
Query Neighborhood Hits	1959	Target Neighborhood Hits	282	Shared Neighborhood Hits	191
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

PSG6_HUMAN
NC score	0.159895 (rank : 1043)	θ value	0.813845 (rank : 1344)
Query Neighborhood Hits	1959	Target Neighborhood Hits	231	Shared Neighborhood Hits	189
SwissProt Accessions	Q00889	Gene names	PSG6, CGM3, PSGGB
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 6 precursor (PSBG-6).

IL1R2_MOUSE
NC score	0.157845 (rank : 1044)	θ value	0.00665767 (rank : 981)
Query Neighborhood Hits	1959	Target Neighborhood Hits	125	Shared Neighborhood Hits	101
SwissProt Accessions	P27931	Gene names	Il1r2, Il-1r2, Il1rb
Domain Architecture
Description	Interleukin-1 receptor type II precursor (IL-1R-2) (IL-1R-beta) (CD121b antigen).

IRPL1_HUMAN
NC score	0.157460 (rank : 1045)	θ value	0.00134147 (rank : 921)
Query Neighborhood Hits	1959	Target Neighborhood Hits	196	Shared Neighborhood Hits	152
SwissProt Accessions	Q9NZN1, Q9UJ53	Gene names	IL1RAPL1, OPHN4
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 1 precursor (IL1RAPL-1) (Oligophrenin-4) (Three immunoglobulin domain-containing IL-1 receptor-related 2) (TIGIRR-2).

CXAR_MOUSE
NC score	0.156895 (rank : 1046)	θ value	θ > 10 (rank : 1996)
Query Neighborhood Hits	1959	Target Neighborhood Hits	250	Shared Neighborhood Hits	161
SwissProt Accessions	P97792, O09052, Q3ULD0, Q91W66, Q99KG0, Q9DBJ8	Gene names	Cxadr, Car
Domain Architecture
Description	Coxsackievirus and adenovirus receptor homolog precursor (CAR) (mCAR).

PSG10_HUMAN
NC score	0.156017 (rank : 1047)	θ value	5.27518 (rank : 1774)
Query Neighborhood Hits	1959	Target Neighborhood Hits	227	Shared Neighborhood Hits	186
SwissProt Accessions	Q15235, O75244, Q15224	Gene names	PSG10, PSG12
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 10 precursor (PSBG-10) (PSBG- 12).

TARSH_HUMAN
NC score	0.155206 (rank : 1048)	θ value	0.0252991 (rank : 1032)
Query Neighborhood Hits	1959	Target Neighborhood Hits	768	Shared Neighborhood Hits	393
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

UNC5D_MOUSE
NC score	0.154748 (rank : 1049)	θ value	0.0431538 (rank : 1065)
Query Neighborhood Hits	1959	Target Neighborhood Hits	268	Shared Neighborhood Hits	179
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

PSG9_HUMAN
NC score	0.154526 (rank : 1050)	θ value	0.47712 (rank : 1265)
Query Neighborhood Hits	1959	Target Neighborhood Hits	221	Shared Neighborhood Hits	186
SwissProt Accessions	Q00887, Q15236, Q15237, Q8WW78, Q9UQ73	Gene names	PSG9, PSG11
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 9 precursor (PSBG-9) (Pregnancy-specific glycoprotein 9) (Pregnancy-specific beta-1 glycoprotein B) (PS-beta-B) (PS34) (Pregnancy-specific glycoprotein 7) (PSG7).

LRRN3_HUMAN
NC score	0.154394 (rank : 1051)	θ value	0.125558 (rank : 1125)
Query Neighborhood Hits	1959	Target Neighborhood Hits	461	Shared Neighborhood Hits	221
SwissProt Accessions	Q9H3W5, O43377, Q6I9V8, Q8IYQ6	Gene names	LRRN3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 3 precursor (Neuronal leucine- rich repeat protein 3) (NLRR-3).

UNC5D_HUMAN
NC score	0.152936 (rank : 1052)	θ value	0.0431538 (rank : 1064)
Query Neighborhood Hits	1959	Target Neighborhood Hits	267	Shared Neighborhood Hits	179
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

FINC_MOUSE
NC score	0.152630 (rank : 1053)	θ value	θ > 10 (rank : 2014)
Query Neighborhood Hits	1959	Target Neighborhood Hits	309	Shared Neighborhood Hits	152
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

PGFRL_HUMAN
NC score	0.151958 (rank : 1054)	θ value	5.27518 (rank : 1771)
Query Neighborhood Hits	1959	Target Neighborhood Hits	115	Shared Neighborhood Hits	111
SwissProt Accessions	Q15198, Q6FH04	Gene names	PDGFRL, PRLTS
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor receptor-like protein precursor (PDGF receptor beta-like tumor suppressor).

CILP1_HUMAN
NC score	0.151858 (rank : 1055)	θ value	0.0193708 (rank : 1016)
Query Neighborhood Hits	1959	Target Neighborhood Hits	266	Shared Neighborhood Hits	171
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

PSG5_HUMAN
NC score	0.151410 (rank : 1056)	θ value	0.365318 (rank : 1230)
Query Neighborhood Hits	1959	Target Neighborhood Hits	231	Shared Neighborhood Hits	188
SwissProt Accessions	Q15238, Q15239, Q96QJ1, Q9UQ75	Gene names	PSG5
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 5 precursor (PSBG-5) (Fetal liver non-specific cross-reactive antigen 3) (FL-NCA-3).

FINC_HUMAN
NC score	0.151216 (rank : 1057)	θ value	0.365318 (rank : 1211)
Query Neighborhood Hits	1959	Target Neighborhood Hits	302	Shared Neighborhood Hits	149
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

CD276_HUMAN
NC score	0.150735 (rank : 1058)	θ value	θ > 10 (rank : 1974)
Query Neighborhood Hits	1959	Target Neighborhood Hits	261	Shared Neighborhood Hits	153
SwissProt Accessions	Q5ZPR3, Q6P5Y4, Q6UXI2, Q8NBI8, Q8NC34, Q8NCB6, Q9BXR1	Gene names	CD276, B7H3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3) (4Ig-B7-H3).

LRRN1_HUMAN
NC score	0.150309 (rank : 1059)	θ value	0.62314 (rank : 1299)
Query Neighborhood Hits	1959	Target Neighborhood Hits	518	Shared Neighborhood Hits	250
SwissProt Accessions	Q6UXK5, Q3LID5, Q8IYV5, Q9H8V1, Q9P231	Gene names	LRRN1, KIAA1497
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 1 precursor (Neuronal leucine- rich repeat protein 1) (NLRR-1).

PECA1_HUMAN
NC score	0.149107 (rank : 1060)	θ value	2.36792 (rank : 1552)
Query Neighborhood Hits	1959	Target Neighborhood Hits	178	Shared Neighborhood Hits	140
SwissProt Accessions	P16284, Q6LDA9, Q8TBH1, Q96RF5, Q96RF6, Q9NP65, Q9NPB7, Q9NPG9, Q9NQS9, Q9NQT0, Q9NQT1, Q9NQT2	Gene names	PECAM1
Domain Architecture
Description	Platelet endothelial cell adhesion molecule precursor (PECAM-1) (EndoCAM) (GPIIA') (CD31 antigen).

LRRN5_HUMAN
NC score	0.146128 (rank : 1061)	θ value	0.00175202 (rank : 933)
Query Neighborhood Hits	1959	Target Neighborhood Hits	493	Shared Neighborhood Hits	240
SwissProt Accessions	O75325, Q5T0Y0, Q6UXM0, Q8N182	Gene names	LRRN5, GAC1, LRRN2
Domain Architecture
Description	Leucine-rich repeats neuronal protein 5 precursor (Glioma amplified on chromosome 1 protein).

LRRN3_MOUSE
NC score	0.146011 (rank : 1062)	θ value	0.21417 (rank : 1161)
Query Neighborhood Hits	1959	Target Neighborhood Hits	455	Shared Neighborhood Hits	221
SwissProt Accessions	Q8CBC6, P97860	Gene names	Lrrn3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 3 precursor (Neuronal leucine- rich repeat protein 3) (NLRR-3).

PRPK_HUMAN
NC score	0.145635 (rank : 1063)	θ value	θ > 10 (rank : 2067)
Query Neighborhood Hits	1959	Target Neighborhood Hits	131	Shared Neighborhood Hits	127
SwissProt Accessions	Q96S44, Q3T977, Q5JZ01, Q96FM7, Q9NQE6	Gene names	TP53RK, C20orf64, PRPK
Domain Architecture
Description	TP53-regulating kinase (EC 2.7.11.1) (p53-related protein kinase) (Nori-2).

LRRN1_MOUSE
NC score	0.144749 (rank : 1064)	θ value	0.365318 (rank : 1220)
Query Neighborhood Hits	1959	Target Neighborhood Hits	508	Shared Neighborhood Hits	247
SwissProt Accessions	Q61809, Q3USY1, Q69ZI0	Gene names	Lrrn1, Kiaa1497
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 1 precursor (Neuronal leucine- rich repeat protein 1) (NLRR-1).

PRPK_MOUSE
NC score	0.144030 (rank : 1065)	θ value	θ > 10 (rank : 2068)
Query Neighborhood Hits	1959	Target Neighborhood Hits	139	Shared Neighborhood Hits	129
SwissProt Accessions	Q99PW4, Q91W37, Q9CZ32	Gene names	Tp53rk, Prpk, Trp53rk
Domain Architecture
Description	TP53-regulating kinase (EC 2.7.11.1) (p53-related protein kinase) (Nori-2).

PVRL3_MOUSE
NC score	0.143248 (rank : 1066)	θ value	3.0926 (rank : 1611)
Query Neighborhood Hits	1959	Target Neighborhood Hits	212	Shared Neighborhood Hits	149
SwissProt Accessions	Q9JLB9, Q9D006, Q9JLB7, Q9JLB8	Gene names	Pvrl3
Domain Architecture	No domain graphic available
Description	Poliovirus receptor-related protein 3 precursor (Cell adhesion molecule nectin-3) (Nectin-3) (CDw113 antigen).

RN5A_HUMAN
NC score	0.140354 (rank : 1067)	θ value	θ > 10 (rank : 2084)
Query Neighborhood Hits	1959	Target Neighborhood Hits	608	Shared Neighborhood Hits	339
SwissProt Accessions	Q05823	Gene names	RNASEL, RNS4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

SIGL7_HUMAN
NC score	0.139548 (rank : 1068)	θ value	0.0330416 (rank : 1047)
Query Neighborhood Hits	1959	Target Neighborhood Hits	180	Shared Neighborhood Hits	156
SwissProt Accessions	Q9Y286, Q9NZQ1, Q9UJ86, Q9UJ87, Q9Y502	Gene names	SIGLEC7, AIRM1
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 7 precursor (Siglec-7) (QA79 membrane protein) (Adhesion inhibitory receptor molecule 1) (AIRM-1) (p75) (D-siglec) (CDw328 antigen).

PVRL3_HUMAN
NC score	0.138620 (rank : 1069)	θ value	0.47712 (rank : 1266)
Query Neighborhood Hits	1959	Target Neighborhood Hits	204	Shared Neighborhood Hits	142
SwissProt Accessions	Q9NQS3, Q6NVZ3, Q8WVU4, Q9BVA9, Q9Y412	Gene names	PVRL3, PRR3
Domain Architecture	No domain graphic available
Description	Poliovirus receptor-related protein 3 precursor (Nectin-3) (CDw113 antigen).

IL6RB_HUMAN
NC score	0.137454 (rank : 1070)	θ value	θ > 10 (rank : 2035)
Query Neighborhood Hits	1959	Target Neighborhood Hits	181	Shared Neighborhood Hits	105
SwissProt Accessions	P40189, Q9UQ41	Gene names	IL6ST
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin M receptor) (CD130 antigen) (CDw130).

PGFRL_MOUSE
NC score	0.137257 (rank : 1071)	θ value	1.81305 (rank : 1505)
Query Neighborhood Hits	1959	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	Q6PE55, Q3V182, Q9D0Z1	Gene names	Pdgfrl
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor receptor-like protein precursor.

LRC24_HUMAN
NC score	0.136611 (rank : 1072)	θ value	0.000461057 (rank : 884)
Query Neighborhood Hits	1959	Target Neighborhood Hits	404	Shared Neighborhood Hits	193
SwissProt Accessions	Q50LG9	Gene names	LRRC24
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 24 precursor.

IL1R1_HUMAN
NC score	0.134474 (rank : 1073)	θ value	1.06291 (rank : 1380)
Query Neighborhood Hits	1959	Target Neighborhood Hits	140	Shared Neighborhood Hits	119
SwissProt Accessions	P14778	Gene names	IL1R1, IL1R, IL1RA, IL1RT1
Domain Architecture
Description	Interleukin-1 receptor type I precursor (IL-1R-1) (IL-1RT1) (IL-1R- alpha) (p80) (CD121a antigen).

SRRM1_MOUSE
NC score	0.133089 (rank : 1074)	θ value	4.45536e-07 (rank : 718)
Query Neighborhood Hits	1959	Target Neighborhood Hits	966	Shared Neighborhood Hits	417
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

USH2A_HUMAN
NC score	0.130331 (rank : 1075)	θ value	0.0193708 (rank : 1023)
Query Neighborhood Hits	1959	Target Neighborhood Hits	600	Shared Neighborhood Hits	161
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

PVRL1_HUMAN
NC score	0.129530 (rank : 1076)	θ value	8.99809 (rank : 1932)
Query Neighborhood Hits	1959	Target Neighborhood Hits	219	Shared Neighborhood Hits	153
SwissProt Accessions	Q15223, O75465, Q9HBE6, Q9HBW2	Gene names	PVRL1, HVEC, PRR1
Domain Architecture
Description	Poliovirus receptor-related protein 1 precursor (Herpes virus entry mediator C) (HveC) (Nectin-1) (Herpesvirus Ig-like receptor) (HIgR) (CD111 antigen).

ILRL2_MOUSE
NC score	0.128829 (rank : 1077)	θ value	0.62314 (rank : 1293)
Query Neighborhood Hits	1959	Target Neighborhood Hits	158	Shared Neighborhood Hits	136
SwissProt Accessions	Q9ERS7	Gene names	Il1rl2
Domain Architecture
Description	Interleukin-1 receptor-like 2 precursor (IL-1Rrp2).

SIG12_MOUSE
NC score	0.127357 (rank : 1078)	θ value	0.813845 (rank : 1351)
Query Neighborhood Hits	1959	Target Neighborhood Hits	225	Shared Neighborhood Hits	163
SwissProt Accessions	Q91Y57	Gene names	Siglec12, Siglec5, Siglece, Siglecl1
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 12 precursor (Siglec-12) (Sialic acid-binding Ig-like lectin-like 1) (Siglec-L1) (Sialic acid-binding Ig-like lectin 5) (Siglec-5) (mSiglec-E) (Myeloid inhibitory siglec) (MIS).

PXK_HUMAN
NC score	0.126655 (rank : 1079)	θ value	θ > 10 (rank : 2079)
Query Neighborhood Hits	1959	Target Neighborhood Hits	216	Shared Neighborhood Hits	154
SwissProt Accessions	Q7Z7A4, Q3BCH4, Q3BCH5, Q3BCH6, Q3BDW1, Q45L83, Q59EX3, Q6PK17, Q6ZN39, Q96CA3, Q96R07, Q9NXB8	Gene names	PXK
Domain Architecture	No domain graphic available
Description	PX domain-containing protein kinase-like protein (Modulator of Na,K- ATPase) (MONaKA).

PIGR_MOUSE
NC score	0.125958 (rank : 1080)	θ value	θ > 10 (rank : 2066)
Query Neighborhood Hits	1959	Target Neighborhood Hits	214	Shared Neighborhood Hits	128
SwissProt Accessions	O70570	Gene names	Pigr
Domain Architecture
Description	Polymeric-immunoglobulin receptor precursor (Poly-Ig receptor) (PIGR) [Contains: Secretory component].

EMB_MOUSE
NC score	0.125252 (rank : 1081)	θ value	θ > 10 (rank : 2005)
Query Neighborhood Hits	1959	Target Neighborhood Hits	83	Shared Neighborhood Hits	73
SwissProt Accessions	P21995, Q3UFF1, Q8C2J8, Q8C543, Q96C38	Gene names	Emb, Gp70
Domain Architecture
Description	Embigin precursor (Teratocarcinoma glycoprotein Gp-70).

LRC4B_MOUSE
NC score	0.125156 (rank : 1082)	θ value	0.00298849 (rank : 956)
Query Neighborhood Hits	1959	Target Neighborhood Hits	484	Shared Neighborhood Hits	218
SwissProt Accessions	P0C192	Gene names	Lrrc4b, Lrig4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4B precursor.

NACAM_MOUSE
NC score	0.124885 (rank : 1083)	θ value	2.21117e-06 (rank : 759)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1866	Shared Neighborhood Hits	634
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NGL1_HUMAN
NC score	0.124757 (rank : 1084)	θ value	0.00228821 (rank : 946)
Query Neighborhood Hits	1959	Target Neighborhood Hits	511	Shared Neighborhood Hits	229
SwissProt Accessions	Q9HCJ2, Q7L0N3	Gene names	LRRC4C, KIAA1580, NGL1
Domain Architecture	No domain graphic available
Description	Netrin-G1 ligand precursor (NGL-1) (Leucine-rich repeat-containing protein 4C).

NGL1_MOUSE
NC score	0.124716 (rank : 1085)	θ value	0.00298849 (rank : 957)
Query Neighborhood Hits	1959	Target Neighborhood Hits	512	Shared Neighborhood Hits	229
SwissProt Accessions	Q8C031, Q8BGH8	Gene names	Lrrc4c, Ngl1
Domain Architecture	No domain graphic available
Description	Netrin-G1 ligand precursor (NGL-1) (Leucine-rich repeat-containing protein 4C).

USH2A_MOUSE
NC score	0.124055 (rank : 1086)	θ value	0.279714 (rank : 1198)
Query Neighborhood Hits	1959	Target Neighborhood Hits	626	Shared Neighborhood Hits	176
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

ILRL1_HUMAN
NC score	0.124023 (rank : 1087)	θ value	0.00228821 (rank : 942)
Query Neighborhood Hits	1959	Target Neighborhood Hits	167	Shared Neighborhood Hits	122
SwissProt Accessions	Q01638, Q53TU7, Q8NEJ3, Q9ULV7, Q9UQ44	Gene names	IL1RL1, DER4, ST2, T1
Domain Architecture
Description	Interleukin-1 receptor-like 1 precursor (ST2 protein).

LRC4B_HUMAN
NC score	0.124008 (rank : 1088)	θ value	0.00298849 (rank : 955)
Query Neighborhood Hits	1959	Target Neighborhood Hits	479	Shared Neighborhood Hits	216
SwissProt Accessions	Q9NT99, Q3ZCQ4, Q58F20	Gene names	LRRC4B, LRIG4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4B precursor.

PECA1_MOUSE
NC score	0.123999 (rank : 1089)	θ value	0.0736092 (rank : 1093)
Query Neighborhood Hits	1959	Target Neighborhood Hits	126	Shared Neighborhood Hits	100
SwissProt Accessions	Q08481	Gene names	Pecam1, Pecam, Pecam-1
Domain Architecture
Description	Platelet endothelial cell adhesion molecule precursor (PECAM-1) (CD31 antigen).

SRRM2_MOUSE
NC score	0.123688 (rank : 1090)	θ value	2.88788e-06 (rank : 764)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1470	Shared Neighborhood Hits	506
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

ITB4_HUMAN
NC score	0.123152 (rank : 1091)	θ value	θ > 10 (rank : 2042)
Query Neighborhood Hits	1959	Target Neighborhood Hits	458	Shared Neighborhood Hits	151
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

UNC5A_HUMAN
NC score	0.123091 (rank : 1092)	θ value	0.0563607 (rank : 1083)
Query Neighborhood Hits	1959	Target Neighborhood Hits	198	Shared Neighborhood Hits	131
SwissProt Accessions	Q6ZN44, Q8TF26, Q96GP4	Gene names	UNC5A, KIAA1976, UNC5H1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

PDL1_HUMAN
NC score	0.121972 (rank : 1093)	θ value	0.813845 (rank : 1339)
Query Neighborhood Hits	1959	Target Neighborhood Hits	195	Shared Neighborhood Hits	132
SwissProt Accessions	Q9NZQ7, Q66RK1, Q6WEX4, Q9NUZ5	Gene names	CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

UNC5C_MOUSE
NC score	0.121586 (rank : 1094)	θ value	1.06291 (rank : 1414)
Query Neighborhood Hits	1959	Target Neighborhood Hits	225	Shared Neighborhood Hits	143
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

MOX2R_MOUSE
NC score	0.121434 (rank : 1095)	θ value	θ > 10 (rank : 2052)
Query Neighborhood Hits	1959	Target Neighborhood Hits	110	Shared Neighborhood Hits	93
SwissProt Accessions	Q9ES57	Gene names	Cd200r1, Mox2r, Ox2r
Domain Architecture	No domain graphic available
Description	Cell surface glycoprotein OX2 receptor precursor (CD200 cell surface glycoprotein receptor).

IL1R1_MOUSE
NC score	0.120941 (rank : 1096)	θ value	8.99809 (rank : 1909)
Query Neighborhood Hits	1959	Target Neighborhood Hits	142	Shared Neighborhood Hits	120
SwissProt Accessions	P13504	Gene names	Il1r1, Il-1r1, Il1ra
Domain Architecture
Description	Interleukin-1 receptor type I precursor (IL-1R-1) (p80) (CD121a antigen).

LRC24_MOUSE
NC score	0.120860 (rank : 1097)	θ value	0.62314 (rank : 1298)
Query Neighborhood Hits	1959	Target Neighborhood Hits	387	Shared Neighborhood Hits	191
SwissProt Accessions	Q8BHA1	Gene names	Lrrc24
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 24 precursor.

UNC5C_HUMAN
NC score	0.120169 (rank : 1098)	θ value	2.36792 (rank : 1571)
Query Neighborhood Hits	1959	Target Neighborhood Hits	226	Shared Neighborhood Hits	139
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

PVRL1_MOUSE
NC score	0.119142 (rank : 1099)	θ value	θ > 10 (rank : 2075)
Query Neighborhood Hits	1959	Target Neighborhood Hits	201	Shared Neighborhood Hits	144
SwissProt Accessions	Q9JKF6, Q9ERL5, Q9JI17	Gene names	Pvrl1, Hvec, Prr1
Domain Architecture
Description	Poliovirus receptor-related protein 1 precursor (Herpes virus entry mediator C) (HveC) (Nectin-1) (CD111 antigen).

SRRM2_HUMAN
NC score	0.118797 (rank : 1100)	θ value	1.80886e-08 (rank : 639)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1296	Shared Neighborhood Hits	457
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

CD276_MOUSE
NC score	0.118353 (rank : 1101)	θ value	θ > 10 (rank : 1975)
Query Neighborhood Hits	1959	Target Neighborhood Hits	243	Shared Neighborhood Hits	156
SwissProt Accessions	Q8VE98	Gene names	Cd276, B7h3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3).

PIGR_HUMAN
NC score	0.116749 (rank : 1102)	θ value	θ > 10 (rank : 2065)
Query Neighborhood Hits	1959	Target Neighborhood Hits	164	Shared Neighborhood Hits	99
SwissProt Accessions	P01833, Q8IZY7	Gene names	PIGR
Domain Architecture
Description	Polymeric-immunoglobulin receptor precursor (Poly-Ig receptor) (PIGR) (Hepatocellular carcinoma-associated protein TB6) [Contains: Secretory component].

IL6RB_MOUSE
NC score	0.116532 (rank : 1103)	θ value	θ > 10 (rank : 2036)
Query Neighborhood Hits	1959	Target Neighborhood Hits	168	Shared Neighborhood Hits	104
SwissProt Accessions	Q00560	Gene names	Il6st
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (CD130 antigen).

HCFC2_MOUSE
NC score	0.115596 (rank : 1104)	θ value	1.38821 (rank : 1436)
Query Neighborhood Hits	1959	Target Neighborhood Hits	97	Shared Neighborhood Hits	88
SwissProt Accessions	Q9D968	Gene names	Hcfc2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

UNC5B_HUMAN
NC score	0.115115 (rank : 1105)	θ value	0.47712 (rank : 1278)
Query Neighborhood Hits	1959	Target Neighborhood Hits	225	Shared Neighborhood Hits	138
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

COCA1_MOUSE
NC score	0.113808 (rank : 1106)	θ value	θ > 10 (rank : 1988)
Query Neighborhood Hits	1959	Target Neighborhood Hits	467	Shared Neighborhood Hits	214
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

UNC5B_MOUSE
NC score	0.112566 (rank : 1107)	θ value	0.47712 (rank : 1279)
Query Neighborhood Hits	1959	Target Neighborhood Hits	226	Shared Neighborhood Hits	139
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

KALM_HUMAN
NC score	0.110890 (rank : 1108)	θ value	θ > 10 (rank : 2044)
Query Neighborhood Hits	1959	Target Neighborhood Hits	114	Shared Neighborhood Hits	71
SwissProt Accessions	P23352	Gene names	KAL1, ADMLX, KAL, KALIG1
Domain Architecture
Description	Anosmin-1 precursor (Kallmann syndrome protein) (Adhesion molecule- like X-linked).

LIFR_HUMAN
NC score	0.110435 (rank : 1109)	θ value	θ > 10 (rank : 2046)
Query Neighborhood Hits	1959	Target Neighborhood Hits	130	Shared Neighborhood Hits	76
SwissProt Accessions	P42702, Q6LCD9	Gene names	LIFR
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (CD118 antigen).

PDL2_MOUSE
NC score	0.110137 (rank : 1110)	θ value	0.813845 (rank : 1340)
Query Neighborhood Hits	1959	Target Neighborhood Hits	116	Shared Neighborhood Hits	90
SwissProt Accessions	Q9WUL5	Gene names	Pdcd1lg2, B7dc, Btdc, Cd273, Pdl2
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 2 precursor (Programmed death ligand 2) (PD-L2) (PD-1-ligand 2) (PDCD1 ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD273 antigen).

LAG3_MOUSE
NC score	0.109876 (rank : 1111)	θ value	0.00665767 (rank : 983)
Query Neighborhood Hits	1959	Target Neighborhood Hits	117	Shared Neighborhood Hits	85
SwissProt Accessions	Q61790, Q0VBL2	Gene names	Lag3
Domain Architecture
Description	Lymphocyte activation gene 3 protein precursor (LAG-3) (CD223 antigen).

PVR_HUMAN
NC score	0.109780 (rank : 1112)	θ value	θ > 10 (rank : 2078)
Query Neighborhood Hits	1959	Target Neighborhood Hits	195	Shared Neighborhood Hits	120
SwissProt Accessions	P15151, P15152, Q15267, Q15268, Q96BJ1	Gene names	PVR, PVS
Domain Architecture
Description	Poliovirus receptor precursor (Nectin-like protein 5) (Necl-5) (CD155 antigen).

LRRC4_HUMAN
NC score	0.109237 (rank : 1113)	θ value	0.0330416 (rank : 1037)
Query Neighborhood Hits	1959	Target Neighborhood Hits	444	Shared Neighborhood Hits	201
SwissProt Accessions	Q9HBW1, Q6ZMI8, Q96A85	Gene names	LRRC4, BAG
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4 precursor (Brain tumor- associated protein LRRC4) (NAG14).

PVRL2_MOUSE
NC score	0.108623 (rank : 1114)	θ value	θ > 10 (rank : 2077)
Query Neighborhood Hits	1959	Target Neighborhood Hits	242	Shared Neighborhood Hits	131
SwissProt Accessions	P32507, Q62096	Gene names	Pvrl2, Mph, Pvr, Pvs
Domain Architecture
Description	Poliovirus receptor-related protein 2 precursor (Murine herpesvirus entry protein B) (mHveB) (Nectin-2) (Poliovirus receptor homolog) (CD112 antigen).

IGS21_HUMAN
NC score	0.108016 (rank : 1115)	θ value	θ > 10 (rank : 2031)
Query Neighborhood Hits	1959	Target Neighborhood Hits	123	Shared Neighborhood Hits	101
SwissProt Accessions	Q96ID5, Q8NBR8	Gene names	IGSF21
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 21 precursor.

UNC5A_MOUSE
NC score	0.107177 (rank : 1116)	θ value	0.62314 (rank : 1310)
Query Neighborhood Hits	1959	Target Neighborhood Hits	203	Shared Neighborhood Hits	127
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

IGS21_MOUSE
NC score	0.107168 (rank : 1117)	θ value	θ > 10 (rank : 2032)
Query Neighborhood Hits	1959	Target Neighborhood Hits	118	Shared Neighborhood Hits	98
SwissProt Accessions	Q7TNR6	Gene names	Igsf21
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 21 precursor.

COCA1_HUMAN
NC score	0.106397 (rank : 1118)	θ value	θ > 10 (rank : 1987)
Query Neighborhood Hits	1959	Target Neighborhood Hits	458	Shared Neighborhood Hits	197
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

SRRM1_HUMAN
NC score	0.105830 (rank : 1119)	θ value	4.1701e-05 (rank : 819)
Query Neighborhood Hits	1959	Target Neighborhood Hits	690	Shared Neighborhood Hits	278
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

MDC1_HUMAN
NC score	0.105078 (rank : 1120)	θ value	0.000602161 (rank : 892)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1446	Shared Neighborhood Hits	467
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

CEAM7_HUMAN
NC score	0.103012 (rank : 1121)	θ value	θ > 10 (rank : 1980)
Query Neighborhood Hits	1959	Target Neighborhood Hits	170	Shared Neighborhood Hits	132
SwissProt Accessions	Q14002, O15148, O15149, Q13983, Q9UPJ2	Gene names	CEACAM7, CGM2
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 7 precursor (Carcinoembryonic antigen CGM2).

I12R2_MOUSE
NC score	0.102844 (rank : 1122)	θ value	θ > 10 (rank : 2027)
Query Neighborhood Hits	1959	Target Neighborhood Hits	143	Shared Neighborhood Hits	92
SwissProt Accessions	P97378	Gene names	Il12rb2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

I12R2_HUMAN
NC score	0.102435 (rank : 1123)	θ value	θ > 10 (rank : 2026)
Query Neighborhood Hits	1959	Target Neighborhood Hits	163	Shared Neighborhood Hits	97
SwissProt Accessions	Q99665	Gene names	IL12RB2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

BUB1B_HUMAN
NC score	0.102275 (rank : 1124)	θ value	θ > 10 (rank : 1972)
Query Neighborhood Hits	1959	Target Neighborhood Hits	208	Shared Neighborhood Hits	119
SwissProt Accessions	O60566, O60501, O60627, O60758, O75389, Q96KM4	Gene names	BUB1B, BUBR1, MAD3L
Domain Architecture
Description	Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (hBUBR1) (MAD3/BUB1-related protein kinase) (Mitotic checkpoint kinase MAD3L) (SSK1).

PTPRM_HUMAN
NC score	0.102112 (rank : 1125)	θ value	θ > 10 (rank : 2071)
Query Neighborhood Hits	1959	Target Neighborhood Hits	244	Shared Neighborhood Hits	135
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

JAML1_MOUSE
NC score	0.101484 (rank : 1126)	θ value	3.0926 (rank : 1594)
Query Neighborhood Hits	1959	Target Neighborhood Hits	185	Shared Neighborhood Hits	110
SwissProt Accessions	Q80UL9, Q5DTC4	Gene names	Amica1, Gm638, Jaml
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule-like precursor (mCrea7).

PRRT3_HUMAN
NC score	0.101223 (rank : 1127)	θ value	0.000602161 (rank : 894)
Query Neighborhood Hits	1959	Target Neighborhood Hits	998	Shared Neighborhood Hits	433
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

LIFR_MOUSE
NC score	0.100894 (rank : 1128)	θ value	θ > 10 (rank : 2047)
Query Neighborhood Hits	1959	Target Neighborhood Hits	127	Shared Neighborhood Hits	70
SwissProt Accessions	P42703	Gene names	Lifr
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (D-factor/LIF receptor) (CD118 antigen).

MDC1_MOUSE
NC score	0.099899 (rank : 1129)	θ value	0.000786445 (rank : 909)
Query Neighborhood Hits	1959	Target Neighborhood Hits	998	Shared Neighborhood Hits	405
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

PTPRM_MOUSE
NC score	0.099662 (rank : 1130)	θ value	θ > 10 (rank : 2072)
Query Neighborhood Hits	1959	Target Neighborhood Hits	238	Shared Neighborhood Hits	134
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

HHLA2_HUMAN
NC score	0.099622 (rank : 1131)	θ value	0.0961366 (rank : 1106)
Query Neighborhood Hits	1959	Target Neighborhood Hits	140	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UM44, Q9NWQ6	Gene names	HHLA2
Domain Architecture	No domain graphic available
Description	HERV-H LTR-associating protein 2 precursor (Human endogenous retrovirus-H long terminal repeat-associating protein 2).

BSN_MOUSE
NC score	0.099022 (rank : 1132)	θ value	0.00298849 (rank : 950)
Query Neighborhood Hits	1959	Target Neighborhood Hits	2057	Shared Neighborhood Hits	624
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

SLAP2_MOUSE
NC score	0.097477 (rank : 1133)	θ value	θ > 10 (rank : 2095)
Query Neighborhood Hits	1959	Target Neighborhood Hits	136	Shared Neighborhood Hits	48
SwissProt Accessions	Q8R4L0, Q3UU74, Q8C0K2, Q8VI42, Q9D1Z9	Gene names	Sla2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2).

PVRL2_HUMAN
NC score	0.096987 (rank : 1134)	θ value	θ > 10 (rank : 2076)
Query Neighborhood Hits	1959	Target Neighborhood Hits	185	Shared Neighborhood Hits	122
SwissProt Accessions	Q92692, O75455, Q96J29	Gene names	PVRL2, HVEB, PRR2
Domain Architecture
Description	Poliovirus receptor-related protein 2 precursor (Herpes virus entry mediator B) (HveB) (Nectin-2) (CD112 antigen).

PDL1_MOUSE
NC score	0.096915 (rank : 1135)	θ value	θ > 10 (rank : 2062)
Query Neighborhood Hits	1959	Target Neighborhood Hits	168	Shared Neighborhood Hits	118
SwissProt Accessions	Q9EP73	Gene names	Cd274, B7h1, Pdcd1l1, Pdcd1lg1, Pdl1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

OGFR_HUMAN
NC score	0.095065 (rank : 1136)	θ value	0.000602161 (rank : 893)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1582	Shared Neighborhood Hits	543
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

SLAP2_HUMAN
NC score	0.094647 (rank : 1137)	θ value	θ > 10 (rank : 2094)
Query Neighborhood Hits	1959	Target Neighborhood Hits	139	Shared Neighborhood Hits	51
SwissProt Accessions	Q9H6Q3, Q5TH27, Q5TH28, Q8WY18, Q96QI4, Q9H135	Gene names	SLA2, C20orf156, SLAP2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2) (Modulator of antigen receptor signaling) (MARS).

LRRC4_MOUSE
NC score	0.093753 (rank : 1138)	θ value	0.21417 (rank : 1160)
Query Neighborhood Hits	1959	Target Neighborhood Hits	412	Shared Neighborhood Hits	175
SwissProt Accessions	Q99PH1, Q8VI35	Gene names	Lrrc4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing 4 protein precursor (Brain tumor- associated protein MBAG1).

SLAP1_HUMAN
NC score	0.093291 (rank : 1139)	θ value	θ > 10 (rank : 2092)
Query Neighborhood Hits	1959	Target Neighborhood Hits	113	Shared Neighborhood Hits	43
SwissProt Accessions	Q13239, Q9UMQ8	Gene names	SLA, SLAP, SLAP1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (hSLAP).

PCLO_MOUSE
NC score	0.092988 (rank : 1140)	θ value	0.00869519 (rank : 996)
Query Neighborhood Hits	1959	Target Neighborhood Hits	2275	Shared Neighborhood Hits	654
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

FCERA_HUMAN
NC score	0.092106 (rank : 1141)	θ value	θ > 10 (rank : 2006)
Query Neighborhood Hits	1959	Target Neighborhood Hits	150	Shared Neighborhood Hits	108
SwissProt Accessions	P12319	Gene names	FCER1A, FCE1A
Domain Architecture
Description	High affinity immunoglobulin epsilon receptor alpha-subunit precursor (FcERI) (IgE Fc receptor, alpha-subunit) (Fc-epsilon RI-alpha).

SLAP1_MOUSE
NC score	0.091961 (rank : 1142)	θ value	θ > 10 (rank : 2093)
Query Neighborhood Hits	1959	Target Neighborhood Hits	117	Shared Neighborhood Hits	43
SwissProt Accessions	Q60898, Q8C9Q8, Q8CAT0, Q8CBE9, Q8QZX8	Gene names	Sla, Slap, Slap1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (mSLAP).

COEA1_MOUSE
NC score	0.089821 (rank : 1143)	θ value	θ > 10 (rank : 1990)
Query Neighborhood Hits	1959	Target Neighborhood Hits	402	Shared Neighborhood Hits	161
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

GRP3_HUMAN
NC score	0.089524 (rank : 1144)	θ value	θ > 10 (rank : 2024)
Query Neighborhood Hits	1959	Target Neighborhood Hits	131	Shared Neighborhood Hits	42
SwissProt Accessions	Q8IV61, O94931	Gene names	RASGRP3, GRP3, KIAA0846
Domain Architecture
Description	RAS guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1).

PCLO_HUMAN
NC score	0.088549 (rank : 1145)	θ value	0.0330416 (rank : 1043)
Query Neighborhood Hits	1959	Target Neighborhood Hits	2046	Shared Neighborhood Hits	576
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

SON_HUMAN
NC score	0.088215 (rank : 1146)	θ value	0.000158464 (rank : 859)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1568	Shared Neighborhood Hits	526
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

NCOA6_HUMAN
NC score	0.087264 (rank : 1147)	θ value	0.00020696 (rank : 866)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1202	Shared Neighborhood Hits	443
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

ILRL1_MOUSE
NC score	0.087202 (rank : 1148)	θ value	θ > 10 (rank : 2040)
Query Neighborhood Hits	1959	Target Neighborhood Hits	172	Shared Neighborhood Hits	123
SwissProt Accessions	P14719, Q05208	Gene names	Il1rl1, Ly84, St2, Ste2
Domain Architecture
Description	Interleukin-1 receptor-like 1 precursor (ST2 protein) (T1 protein) (Lymphocyte antigen 84).

PTPRU_HUMAN
NC score	0.087000 (rank : 1149)	θ value	3.0926 (rank : 1610)
Query Neighborhood Hits	1959	Target Neighborhood Hits	237	Shared Neighborhood Hits	129
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

FCGR1_HUMAN
NC score	0.086972 (rank : 1150)	θ value	θ > 10 (rank : 2009)
Query Neighborhood Hits	1959	Target Neighborhood Hits	145	Shared Neighborhood Hits	99
SwissProt Accessions	P12314, P12315, Q92495, Q92663	Gene names	FCGR1A, FCG1, FCGR1, IGFR1
Domain Architecture
Description	High affinity immunoglobulin gamma Fc receptor I precursor (Fc-gamma RI) (FcRI) (IgG Fc receptor I) (CD64 antigen).

OX2G_MOUSE
NC score	0.086971 (rank : 1151)	θ value	θ > 10 (rank : 2059)
Query Neighborhood Hits	1959	Target Neighborhood Hits	105	Shared Neighborhood Hits	82
SwissProt Accessions	O54901, O54816, Q9JHD5	Gene names	Cd200, Mox2
Domain Architecture
Description	OX-2 membrane glycoprotein precursor (MRC OX-2 antigen) (CD200 antigen).

BSN_HUMAN
NC score	0.086890 (rank : 1152)	θ value	0.0193708 (rank : 1015)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1537	Shared Neighborhood Hits	486
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

RGS3_MOUSE
NC score	0.086747 (rank : 1153)	θ value	0.000786445 (rank : 910)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1621	Shared Neighborhood Hits	557
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

PTPRT_MOUSE
NC score	0.086344 (rank : 1154)	θ value	θ > 10 (rank : 2074)
Query Neighborhood Hits	1959	Target Neighborhood Hits	219	Shared Neighborhood Hits	113
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

PTPRT_HUMAN
NC score	0.085742 (rank : 1155)	θ value	θ > 10 (rank : 2073)
Query Neighborhood Hits	1959	Target Neighborhood Hits	217	Shared Neighborhood Hits	112
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

LAG3_HUMAN
NC score	0.084902 (rank : 1156)	θ value	θ > 10 (rank : 2045)
Query Neighborhood Hits	1959	Target Neighborhood Hits	129	Shared Neighborhood Hits	80
SwissProt Accessions	P18627	Gene names	LAG3, FDC
Domain Architecture
Description	Lymphocyte activation gene 3 protein precursor (LAG-3) (FDC protein) (CD223 antigen).

PRP2_MOUSE
NC score	0.084426 (rank : 1157)	θ value	0.21417 (rank : 1168)
Query Neighborhood Hits	1959	Target Neighborhood Hits	347	Shared Neighborhood Hits	175
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PRG4_HUMAN
NC score	0.084057 (rank : 1158)	θ value	0.00509761 (rank : 974)
Query Neighborhood Hits	1959	Target Neighborhood Hits	764	Shared Neighborhood Hits	305
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

LCP2_HUMAN
NC score	0.083660 (rank : 1159)	θ value	0.00020696 (rank : 863)
Query Neighborhood Hits	1959	Target Neighborhood Hits	531	Shared Neighborhood Hits	246
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

STAC_MOUSE
NC score	0.083443 (rank : 1160)	θ value	θ > 10 (rank : 2100)
Query Neighborhood Hits	1959	Target Neighborhood Hits	268	Shared Neighborhood Hits	92
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

BUB1B_MOUSE
NC score	0.083005 (rank : 1161)	θ value	θ > 10 (rank : 1973)
Query Neighborhood Hits	1959	Target Neighborhood Hits	202	Shared Neighborhood Hits	135
SwissProt Accessions	Q9Z1S0	Gene names	Bub1b, Mad3l
Domain Architecture
Description	Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (MAD3/BUB1-related protein kinase) (Mitotic checkpoint kinase MAD3L).

CO7A1_HUMAN
NC score	0.082320 (rank : 1162)	θ value	8.99809 (rank : 1886)
Query Neighborhood Hits	1959	Target Neighborhood Hits	807	Shared Neighborhood Hits	281
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

MUC1_HUMAN
NC score	0.082289 (rank : 1163)	θ value	5.81887e-07 (rank : 724)
Query Neighborhood Hits	1959	Target Neighborhood Hits	975	Shared Neighborhood Hits	398
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

MUC7_HUMAN
NC score	0.082202 (rank : 1164)	θ value	0.0431538 (rank : 1060)
Query Neighborhood Hits	1959	Target Neighborhood Hits	538	Shared Neighborhood Hits	246
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

PRR12_HUMAN
NC score	0.081983 (rank : 1165)	θ value	0.00665767 (rank : 986)
Query Neighborhood Hits	1959	Target Neighborhood Hits	460	Shared Neighborhood Hits	217
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

WASIP_HUMAN
NC score	0.081967 (rank : 1166)	θ value	0.0563607 (rank : 1084)
Query Neighborhood Hits	1959	Target Neighborhood Hits	458	Shared Neighborhood Hits	219
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

CD79A_HUMAN
NC score	0.081182 (rank : 1167)	θ value	θ > 10 (rank : 1977)
Query Neighborhood Hits	1959	Target Neighborhood Hits	102	Shared Neighborhood Hits	62
SwissProt Accessions	P11912	Gene names	CD79A, IGA, MB1
Domain Architecture
Description	B-cell antigen receptor complex-associated protein alpha-chain precursor (Ig-alpha) (MB-1 membrane glycoprotein) (Surface IgM- associated protein) (Membrane-bound immunoglobulin-associated protein) (CD79a antigen).

STAC3_MOUSE
NC score	0.080965 (rank : 1168)	θ value	θ > 10 (rank : 2098)
Query Neighborhood Hits	1959	Target Neighborhood Hits	232	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

PRP1_HUMAN
NC score	0.080909 (rank : 1169)	θ value	0.0736092 (rank : 1094)
Query Neighborhood Hits	1959	Target Neighborhood Hits	385	Shared Neighborhood Hits	179
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PDL2_HUMAN
NC score	0.080824 (rank : 1170)	θ value	θ > 10 (rank : 2063)
Query Neighborhood Hits	1959	Target Neighborhood Hits	114	Shared Neighborhood Hits	80
SwissProt Accessions	Q9BQ51, Q5T7Z6, Q6JXL8, Q6JXL9	Gene names	PDCD1LG2, B7DC, CD273, PDCD1L2, PDL2
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 2 precursor (Programmed death ligand 2) (PD-L2) (PD-1-ligand 2) (PDCD1 ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD273 antigen).

CSF3R_HUMAN
NC score	0.080618 (rank : 1171)	θ value	θ > 10 (rank : 1992)
Query Neighborhood Hits	1959	Target Neighborhood Hits	140	Shared Neighborhood Hits	79
SwissProt Accessions	Q99062	Gene names	CSF3R, GCSFR
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

CD80_HUMAN
NC score	0.080538 (rank : 1172)	θ value	θ > 10 (rank : 1978)
Query Neighborhood Hits	1959	Target Neighborhood Hits	129	Shared Neighborhood Hits	91
SwissProt Accessions	P33681	Gene names	CD80, CD28LG, CD28LG1, LAB7
Domain Architecture
Description	T-lymphocyte activation antigen CD80 precursor (Activation B7-1 antigen) (CTLA-4 counter-receptor B7.1) (B7) (BB1).

STAC3_HUMAN
NC score	0.080259 (rank : 1173)	θ value	θ > 10 (rank : 2097)
Query Neighborhood Hits	1959	Target Neighborhood Hits	228	Shared Neighborhood Hits	74
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

BAT2_HUMAN
NC score	0.079842 (rank : 1174)	θ value	0.0736092 (rank : 1087)
Query Neighborhood Hits	1959	Target Neighborhood Hits	931	Shared Neighborhood Hits	384
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

PTPRK_MOUSE
NC score	0.079370 (rank : 1175)	θ value	θ > 10 (rank : 2070)
Query Neighborhood Hits	1959	Target Neighborhood Hits	223	Shared Neighborhood Hits	118
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

TARA_HUMAN
NC score	0.079219 (rank : 1176)	θ value	0.0330416 (rank : 1049)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1626	Shared Neighborhood Hits	463
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

NCOA6_MOUSE
NC score	0.078683 (rank : 1177)	θ value	0.0330416 (rank : 1040)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1076	Shared Neighborhood Hits	388
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

TENR_HUMAN
NC score	0.078479 (rank : 1178)	θ value	θ > 10 (rank : 2102)
Query Neighborhood Hits	1959	Target Neighborhood Hits	526	Shared Neighborhood Hits	142
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

CD80_MOUSE
NC score	0.078328 (rank : 1179)	θ value	θ > 10 (rank : 1979)
Query Neighborhood Hits	1959	Target Neighborhood Hits	136	Shared Neighborhood Hits	93
SwissProt Accessions	Q00609, Q61332	Gene names	Cd80, B7
Domain Architecture
Description	T-lymphocyte activation antigen CD80 precursor (Activation B7-1 antigen) (B7).

PTPRK_HUMAN
NC score	0.078157 (rank : 1180)	θ value	θ > 10 (rank : 2069)
Query Neighborhood Hits	1959	Target Neighborhood Hits	228	Shared Neighborhood Hits	120
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

TENN_MOUSE
NC score	0.077394 (rank : 1181)	θ value	8.99809 (rank : 1944)
Query Neighborhood Hits	1959	Target Neighborhood Hits	484	Shared Neighborhood Hits	130
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

ICAM1_MOUSE
NC score	0.077363 (rank : 1182)	θ value	θ > 10 (rank : 2029)
Query Neighborhood Hits	1959	Target Neighborhood Hits	99	Shared Neighborhood Hits	86
SwissProt Accessions	P13597, Q61828	Gene names	Icam1, Icam-1
Domain Architecture
Description	Intercellular adhesion molecule 1 precursor (ICAM-1) (MALA-2).

STAC_HUMAN
NC score	0.077314 (rank : 1183)	θ value	θ > 10 (rank : 2099)
Query Neighborhood Hits	1959	Target Neighborhood Hits	276	Shared Neighborhood Hits	91
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

ILRL2_HUMAN
NC score	0.077051 (rank : 1184)	θ value	θ > 10 (rank : 2041)
Query Neighborhood Hits	1959	Target Neighborhood Hits	112	Shared Neighborhood Hits	91
SwissProt Accessions	Q9HB29, Q13525, Q45H74	Gene names	IL1RL2, IL1RRP2
Domain Architecture
Description	Interleukin-1 receptor-like 2 precursor (IL-1Rrp2) (Interleukin-1 receptor-related protein 2) (IL1R-rp2).

GSCR1_HUMAN
NC score	0.076267 (rank : 1185)	θ value	0.0252991 (rank : 1028)
Query Neighborhood Hits	1959	Target Neighborhood Hits	674	Shared Neighborhood Hits	295
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

PRG4_MOUSE
NC score	0.075924 (rank : 1186)	θ value	0.00509761 (rank : 975)
Query Neighborhood Hits	1959	Target Neighborhood Hits	624	Shared Neighborhood Hits	242
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

DCX_HUMAN
NC score	0.075252 (rank : 1187)	θ value	θ > 10 (rank : 1999)
Query Neighborhood Hits	1959	Target Neighborhood Hits	141	Shared Neighborhood Hits	74
SwissProt Accessions	O43602, O43911	Gene names	DCX, DBCN, LISX
Domain Architecture
Description	Neuronal migration protein doublecortin (Lissencephalin-X) (Lis-X) (Doublin).

OX2G_HUMAN
NC score	0.074893 (rank : 1188)	θ value	θ > 10 (rank : 2058)
Query Neighborhood Hits	1959	Target Neighborhood Hits	100	Shared Neighborhood Hits	75
SwissProt Accessions	P41217, Q6J2Q6, Q6PIQ4, Q8TB85, Q9H3J3	Gene names	CD200, MOX2
Domain Architecture
Description	OX-2 membrane glycoprotein precursor (CD200 antigen).

TENR_MOUSE
NC score	0.074827 (rank : 1189)	θ value	θ > 10 (rank : 2103)
Query Neighborhood Hits	1959	Target Neighborhood Hits	531	Shared Neighborhood Hits	136
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

MFAP3_HUMAN
NC score	0.074539 (rank : 1190)	θ value	θ > 10 (rank : 2049)
Query Neighborhood Hits	1959	Target Neighborhood Hits	91	Shared Neighborhood Hits	82
SwissProt Accessions	P55082, Q9NXA7	Gene names	MFAP3
Domain Architecture
Description	Microfibril-associated glycoprotein 3 precursor.

NFH_MOUSE
NC score	0.074492 (rank : 1191)	θ value	4.92598e-06 (rank : 772)
Query Neighborhood Hits	1959	Target Neighborhood Hits	2247	Shared Neighborhood Hits	613
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

WASIP_MOUSE
NC score	0.074444 (rank : 1192)	θ value	0.365318 (rank : 1242)
Query Neighborhood Hits	1959	Target Neighborhood Hits	392	Shared Neighborhood Hits	204
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

HCFC2_HUMAN
NC score	0.074422 (rank : 1193)	θ value	0.47712 (rank : 1256)
Query Neighborhood Hits	1959	Target Neighborhood Hits	154	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Y5Z7	Gene names	HCFC2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

RGS3_HUMAN
NC score	0.074303 (rank : 1194)	θ value	0.00228821 (rank : 947)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1375	Shared Neighborhood Hits	452
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

SORL_HUMAN
NC score	0.074296 (rank : 1195)	θ value	4.03905 (rank : 1695)
Query Neighborhood Hits	1959	Target Neighborhood Hits	440	Shared Neighborhood Hits	118
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

PDZD8_HUMAN
NC score	0.074187 (rank : 1196)	θ value	θ > 10 (rank : 2064)
Query Neighborhood Hits	1959	Target Neighborhood Hits	185	Shared Neighborhood Hits	68
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

PRB4S_HUMAN
NC score	0.073767 (rank : 1197)	θ value	8.99809 (rank : 1929)
Query Neighborhood Hits	1959	Target Neighborhood Hits	330	Shared Neighborhood Hits	165
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

ALEX_HUMAN
NC score	0.073715 (rank : 1198)	θ value	0.0113563 (rank : 999)
Query Neighborhood Hits	1959	Target Neighborhood Hits	361	Shared Neighborhood Hits	195
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

VAV_HUMAN
NC score	0.073607 (rank : 1199)	θ value	θ > 10 (rank : 2116)
Query Neighborhood Hits	1959	Target Neighborhood Hits	452	Shared Neighborhood Hits	111
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

GRAP_HUMAN
NC score	0.073590 (rank : 1200)	θ value	θ > 10 (rank : 2020)
Query Neighborhood Hits	1959	Target Neighborhood Hits	307	Shared Neighborhood Hits	80
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

COEA1_HUMAN
NC score	0.073370 (rank : 1201)	θ value	θ > 10 (rank : 1989)
Query Neighborhood Hits	1959	Target Neighborhood Hits	427	Shared Neighborhood Hits	169
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

BASP_MOUSE
NC score	0.073021 (rank : 1202)	θ value	1.81305 (rank : 1469)
Query Neighborhood Hits	1959	Target Neighborhood Hits	260	Shared Neighborhood Hits	114
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

SORL_MOUSE
NC score	0.072806 (rank : 1203)	θ value	θ > 10 (rank : 2096)
Query Neighborhood Hits	1959	Target Neighborhood Hits	439	Shared Neighborhood Hits	125
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

BASP_HUMAN
NC score	0.072615 (rank : 1204)	θ value	0.0563607 (rank : 1067)
Query Neighborhood Hits	1959	Target Neighborhood Hits	321	Shared Neighborhood Hits	133
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

VAV3_HUMAN
NC score	0.072391 (rank : 1205)	θ value	θ > 10 (rank : 2114)
Query Neighborhood Hits	1959	Target Neighborhood Hits	398	Shared Neighborhood Hits	107
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

GRAP_MOUSE
NC score	0.072388 (rank : 1206)	θ value	θ > 10 (rank : 2021)
Query Neighborhood Hits	1959	Target Neighborhood Hits	309	Shared Neighborhood Hits	79
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

VAV3_MOUSE
NC score	0.072365 (rank : 1207)	θ value	θ > 10 (rank : 2115)
Query Neighborhood Hits	1959	Target Neighborhood Hits	404	Shared Neighborhood Hits	112
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

SELPL_MOUSE
NC score	0.072321 (rank : 1208)	θ value	0.47712 (rank : 1267)
Query Neighborhood Hits	1959	Target Neighborhood Hits	588	Shared Neighborhood Hits	269
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

ICAM1_HUMAN
NC score	0.072135 (rank : 1209)	θ value	θ > 10 (rank : 2028)
Query Neighborhood Hits	1959	Target Neighborhood Hits	80	Shared Neighborhood Hits	67
SwissProt Accessions	P05362, Q96B50	Gene names	ICAM1
Domain Architecture
Description	Intercellular adhesion molecule 1 precursor (ICAM-1) (Major group rhinovirus receptor) (CD54 antigen).

RASF1_MOUSE
NC score	0.071238 (rank : 1210)	θ value	θ > 10 (rank : 2082)
Query Neighborhood Hits	1959	Target Neighborhood Hits	74	Shared Neighborhood Hits	35
SwissProt Accessions	Q99MK9, Q9WUF5	Gene names	Rassf1
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 1 (Protein 123F2).

TXND2_HUMAN
NC score	0.070904 (rank : 1211)	θ value	1.38821 (rank : 1461)
Query Neighborhood Hits	1959	Target Neighborhood Hits	793	Shared Neighborhood Hits	275
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

UN13A_HUMAN
NC score	0.070468 (rank : 1212)	θ value	θ > 10 (rank : 2109)
Query Neighborhood Hits	1959	Target Neighborhood Hits	285	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

DCX_MOUSE
NC score	0.070402 (rank : 1213)	θ value	θ > 10 (rank : 2000)
Query Neighborhood Hits	1959	Target Neighborhood Hits	124	Shared Neighborhood Hits	46
SwissProt Accessions	O88809	Gene names	Dcx, Dcn
Domain Architecture
Description	Neuronal migration protein doublecortin (Lissencephalin-X) (Lis-X) (Doublin).

MFAP3_MOUSE
NC score	0.070172 (rank : 1214)	θ value	5.27518 (rank : 1763)
Query Neighborhood Hits	1959	Target Neighborhood Hits	97	Shared Neighborhood Hits	86
SwissProt Accessions	Q922T2, Q8BHK5	Gene names	Mfap3
Domain Architecture	No domain graphic available
Description	Microfibril-associated glycoprotein 3 precursor.

VAV2_HUMAN
NC score	0.070123 (rank : 1215)	θ value	θ > 10 (rank : 2112)
Query Neighborhood Hits	1959	Target Neighborhood Hits	453	Shared Neighborhood Hits	115
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

ICAM3_HUMAN
NC score	0.069803 (rank : 1216)	θ value	θ > 10 (rank : 2030)
Query Neighborhood Hits	1959	Target Neighborhood Hits	100	Shared Neighborhood Hits	82
SwissProt Accessions	P32942	Gene names	ICAM3
Domain Architecture
Description	Intercellular adhesion molecule 3 precursor (ICAM-3) (ICAM-R) (CDw50) (CD50 antigen).

GRB2_HUMAN
NC score	0.069784 (rank : 1217)	θ value	θ > 10 (rank : 2022)
Query Neighborhood Hits	1959	Target Neighborhood Hits	310	Shared Neighborhood Hits	76
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
NC score	0.069716 (rank : 1218)	θ value	θ > 10 (rank : 2023)
Query Neighborhood Hits	1959	Target Neighborhood Hits	312	Shared Neighborhood Hits	76
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

GRAP2_HUMAN
NC score	0.069574 (rank : 1219)	θ value	θ > 10 (rank : 2018)
Query Neighborhood Hits	1959	Target Neighborhood Hits	304	Shared Neighborhood Hits	73
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

MAGE1_HUMAN
NC score	0.069434 (rank : 1220)	θ value	0.00175202 (rank : 934)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1389	Shared Neighborhood Hits	486
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

TGON2_HUMAN
NC score	0.069393 (rank : 1221)	θ value	4.03905 (rank : 1698)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1037	Shared Neighborhood Hits	332
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TAF4_HUMAN
NC score	0.069385 (rank : 1222)	θ value	3.0926 (rank : 1624)
Query Neighborhood Hits	1959	Target Neighborhood Hits	687	Shared Neighborhood Hits	263
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

PACE1_MOUSE
NC score	0.068849 (rank : 1223)	θ value	θ > 10 (rank : 2061)
Query Neighborhood Hits	1959	Target Neighborhood Hits	92	Shared Neighborhood Hits	64
SwissProt Accessions	Q9DBQ7, Q6NY01, Q8BQC9, Q8BRJ1	Gene names	Scyl3, Pace1
Domain Architecture	No domain graphic available
Description	Protein-associating with the carboxyl-terminal domain of ezrin (Ezrin- binding protein PACE-1) (SCY1-like protein 3).

VAV_MOUSE
NC score	0.068836 (rank : 1224)	θ value	θ > 10 (rank : 2117)
Query Neighborhood Hits	1959	Target Neighborhood Hits	430	Shared Neighborhood Hits	108
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

WIRE_HUMAN
NC score	0.068809 (rank : 1225)	θ value	0.00509761 (rank : 978)
Query Neighborhood Hits	1959	Target Neighborhood Hits	329	Shared Neighborhood Hits	178
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

SPR1B_MOUSE
NC score	0.068722 (rank : 1226)	θ value	0.00298849 (rank : 959)
Query Neighborhood Hits	1959	Target Neighborhood Hits	395	Shared Neighborhood Hits	189
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

EMB_HUMAN
NC score	0.068700 (rank : 1227)	θ value	θ > 10 (rank : 2004)
Query Neighborhood Hits	1959	Target Neighborhood Hits	54	Shared Neighborhood Hits	42
SwissProt Accessions	Q6PCB8	Gene names	EMB
Domain Architecture	No domain graphic available
Description	Embigin precursor.

GRIN1_HUMAN
NC score	0.068555 (rank : 1228)	θ value	0.00390308 (rank : 962)
Query Neighborhood Hits	1959	Target Neighborhood Hits	681	Shared Neighborhood Hits	274
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

DGKD_HUMAN
NC score	0.068284 (rank : 1229)	θ value	θ > 10 (rank : 2001)
Query Neighborhood Hits	1959	Target Neighborhood Hits	231	Shared Neighborhood Hits	91
SwissProt Accessions	Q16760, Q14158, Q6PK55, Q8NG53	Gene names	DGKD, KIAA0145
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase delta (EC 2.7.1.107) (Diglyceride kinase delta) (DGK-delta) (DAG kinase delta) (130 kDa diacylglycerol kinase).

GRAP2_MOUSE
NC score	0.068111 (rank : 1230)	θ value	θ > 10 (rank : 2019)
Query Neighborhood Hits	1959	Target Neighborhood Hits	297	Shared Neighborhood Hits	71
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

CT075_HUMAN
NC score	0.067738 (rank : 1231)	θ value	θ > 10 (rank : 1994)
Query Neighborhood Hits	1959	Target Neighborhood Hits	387	Shared Neighborhood Hits	128
SwissProt Accessions	Q8WUT4, Q5JWV6, Q9H419	Gene names	C20orf75
Domain Architecture
Description	Uncharacterized protein C20orf75 precursor.

VAV2_MOUSE
NC score	0.067714 (rank : 1232)	θ value	θ > 10 (rank : 2113)
Query Neighborhood Hits	1959	Target Neighborhood Hits	456	Shared Neighborhood Hits	115
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

WASL_HUMAN
NC score	0.067680 (rank : 1233)	θ value	0.0148317 (rank : 1014)
Query Neighborhood Hits	1959	Target Neighborhood Hits	312	Shared Neighborhood Hits	170
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

BAT2_MOUSE
NC score	0.067621 (rank : 1234)	θ value	0.0431538 (rank : 1053)
Query Neighborhood Hits	1959	Target Neighborhood Hits	947	Shared Neighborhood Hits	384
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CN155_HUMAN
NC score	0.067423 (rank : 1235)	θ value	5.27518 (rank : 1725)
Query Neighborhood Hits	1959	Target Neighborhood Hits	385	Shared Neighborhood Hits	181
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

LAD1_MOUSE
NC score	0.067235 (rank : 1236)	θ value	0.47712 (rank : 1260)
Query Neighborhood Hits	1959	Target Neighborhood Hits	391	Shared Neighborhood Hits	164
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

NCK1_HUMAN
NC score	0.066984 (rank : 1237)	θ value	θ > 10 (rank : 2053)
Query Neighborhood Hits	1959	Target Neighborhood Hits	312	Shared Neighborhood Hits	73
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

NCK2_HUMAN
NC score	0.066948 (rank : 1238)	θ value	θ > 10 (rank : 2054)
Query Neighborhood Hits	1959	Target Neighborhood Hits	310	Shared Neighborhood Hits	75
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

IGSF2_HUMAN
NC score	0.066923 (rank : 1239)	θ value	θ > 10 (rank : 2033)
Query Neighborhood Hits	1959	Target Neighborhood Hits	208	Shared Neighborhood Hits	94
SwissProt Accessions	Q93033, Q15856	Gene names	IGSF2, CD101, EWI101, V7
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 2 precursor (Glu-Trp-Ile EWI motif- containing protein 101) (EWI-101) (Cell surface glycoprotein V7) (CD101 antigen).

UN13B_HUMAN
NC score	0.066624 (rank : 1240)	θ value	θ > 10 (rank : 2110)
Query Neighborhood Hits	1959	Target Neighborhood Hits	217	Shared Neighborhood Hits	54
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

FCGR1_MOUSE
NC score	0.066540 (rank : 1241)	θ value	θ > 10 (rank : 2010)
Query Neighborhood Hits	1959	Target Neighborhood Hits	123	Shared Neighborhood Hits	87
SwissProt Accessions	P26151	Gene names	Fcgr1, Fcg1
Domain Architecture
Description	High affinity immunoglobulin gamma Fc receptor I precursor (Fc-gamma RI) (FcRI) (IgG Fc receptor I).

CS016_HUMAN
NC score	0.066529 (rank : 1242)	θ value	0.0148317 (rank : 1007)
Query Neighborhood Hits	1959	Target Neighborhood Hits	310	Shared Neighborhood Hits	160
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

CHIO_HUMAN
NC score	0.066348 (rank : 1243)	θ value	θ > 10 (rank : 1984)
Query Neighborhood Hits	1959	Target Neighborhood Hits	220	Shared Neighborhood Hits	66
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

TENN_HUMAN
NC score	0.066335 (rank : 1244)	θ value	0.365318 (rank : 1239)
Query Neighborhood Hits	1959	Target Neighborhood Hits	453	Shared Neighborhood Hits	118
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

FA47A_HUMAN
NC score	0.066091 (rank : 1245)	θ value	1.06291 (rank : 1372)
Query Neighborhood Hits	1959	Target Neighborhood Hits	451	Shared Neighborhood Hits	219
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

FA47B_HUMAN
NC score	0.066084 (rank : 1246)	θ value	1.38821 (rank : 1430)
Query Neighborhood Hits	1959	Target Neighborhood Hits	431	Shared Neighborhood Hits	210
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

CHIN_MOUSE
NC score	0.065730 (rank : 1247)	θ value	θ > 10 (rank : 1983)
Query Neighborhood Hits	1959	Target Neighborhood Hits	229	Shared Neighborhood Hits	68
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

SON_MOUSE
NC score	0.065711 (rank : 1248)	θ value	0.125558 (rank : 1131)
Query Neighborhood Hits	1959	Target Neighborhood Hits	957	Shared Neighborhood Hits	351
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

SIGL9_HUMAN
NC score	0.065460 (rank : 1249)	θ value	θ > 10 (rank : 2090)
Query Neighborhood Hits	1959	Target Neighborhood Hits	76	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y336, Q9BYI9	Gene names	SIGLEC9
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 9 precursor (Siglec-9) (Protein FOAP-9).

SHPS1_HUMAN
NC score	0.065345 (rank : 1250)	θ value	θ > 10 (rank : 2089)
Query Neighborhood Hits	1959	Target Neighborhood Hits	455	Shared Neighborhood Hits	111
SwissProt Accessions	P78324, O00683, O43799, Q8N517, Q8TAL8, Q9H0Z2, Q9UDX2, Q9UIJ6, Q9Y4U9	Gene names	SIRPA, BIT, MFR, MYD1, PTPNS1, SHPS1, SIRP
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type substrate 1 precursor (SHP substrate 1) (SHPS-1) (Inhibitory receptor SHPS-1) (Signal- regulatory protein alpha-1) (Sirp-alpha-1) (Sirp-alpha-2) (Sirp-alpha- 3) (MyD-1 antigen) (Brain Ig-like molecule with tyrosine-based activation motifs) (Bit) (Macrophage fusion receptor) (p84) (CD172a antigen).

COKA1_HUMAN
NC score	0.065241 (rank : 1251)	θ value	θ > 10 (rank : 1991)
Query Neighborhood Hits	1959	Target Neighborhood Hits	403	Shared Neighborhood Hits	162
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

CHIN_HUMAN
NC score	0.065183 (rank : 1252)	θ value	θ > 10 (rank : 1982)
Query Neighborhood Hits	1959	Target Neighborhood Hits	227	Shared Neighborhood Hits	67
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

PACE1_HUMAN
NC score	0.065165 (rank : 1253)	θ value	θ > 10 (rank : 2060)
Query Neighborhood Hits	1959	Target Neighborhood Hits	74	Shared Neighborhood Hits	54
SwissProt Accessions	Q8IZE3, Q5THA6, Q5THA8, Q8IZN9, Q96C56, Q9UBK6	Gene names	SCYL3, PACE1
Domain Architecture	No domain graphic available
Description	Protein-associating with the carboxyl-terminal domain of ezrin (Ezrin- binding protein PACE-1) (SCY1-like protein 3).

MBD6_HUMAN
NC score	0.064914 (rank : 1254)	θ value	6.88961 (rank : 1832)
Query Neighborhood Hits	1959	Target Neighborhood Hits	349	Shared Neighborhood Hits	167
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

PRB3_HUMAN
NC score	0.064735 (rank : 1255)	θ value	1.06291 (rank : 1400)
Query Neighborhood Hits	1959	Target Neighborhood Hits	318	Shared Neighborhood Hits	160
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

CK024_HUMAN
NC score	0.064609 (rank : 1256)	θ value	θ > 10 (rank : 1986)
Query Neighborhood Hits	1959	Target Neighborhood Hits	408	Shared Neighborhood Hits	214
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

T22D4_HUMAN
NC score	0.064493 (rank : 1257)	θ value	0.00134147 (rank : 929)
Query Neighborhood Hits	1959	Target Neighborhood Hits	403	Shared Neighborhood Hits	207
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

UN13B_MOUSE
NC score	0.064304 (rank : 1258)	θ value	θ > 10 (rank : 2111)
Query Neighborhood Hits	1959	Target Neighborhood Hits	210	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

PI5PA_HUMAN
NC score	0.064006 (rank : 1259)	θ value	0.0193708 (rank : 1021)
Query Neighborhood Hits	1959	Target Neighborhood Hits	749	Shared Neighborhood Hits	349
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

FPRP_HUMAN
NC score	0.063988 (rank : 1260)	θ value	θ > 10 (rank : 2015)
Query Neighborhood Hits	1959	Target Neighborhood Hits	130	Shared Neighborhood Hits	85
SwissProt Accessions	Q9P2B2, Q8N2K6	Gene names	PTGFRN, CD9P1, FPRP, KIAA1436
Domain Architecture
Description	Prostaglandin F2 receptor negative regulator precursor (Prostaglandin F2-alpha receptor regulatory protein) (Prostaglandin F2-alpha receptor-associated protein) (CD9 partner 1) (CD9P-1) (CD315 antigen).

DGKH_HUMAN
NC score	0.063661 (rank : 1261)	θ value	θ > 10 (rank : 2002)
Query Neighborhood Hits	1959	Target Neighborhood Hits	255	Shared Neighborhood Hits	87
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

MBB1A_HUMAN
NC score	0.063446 (rank : 1262)	θ value	0.0431538 (rank : 1059)
Query Neighborhood Hits	1959	Target Neighborhood Hits	665	Shared Neighborhood Hits	269
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

SH21B_MOUSE
NC score	0.063334 (rank : 1263)	θ value	θ > 10 (rank : 2088)
Query Neighborhood Hits	1959	Target Neighborhood Hits	101	Shared Neighborhood Hits	44
SwissProt Accessions	O35324, Q8C268	Gene names	Sh2d1b, Eat2, Sh2d1b1
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

WIRE_MOUSE
NC score	0.063312 (rank : 1264)	θ value	0.0193708 (rank : 1025)
Query Neighborhood Hits	1959	Target Neighborhood Hits	310	Shared Neighborhood Hits	168
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

IASPP_MOUSE
NC score	0.062935 (rank : 1265)	θ value	0.0563607 (rank : 1073)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1024	Shared Neighborhood Hits	344
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

WASL_MOUSE
NC score	0.062821 (rank : 1266)	θ value	0.0330416 (rank : 1052)
Query Neighborhood Hits	1959	Target Neighborhood Hits	339	Shared Neighborhood Hits	172
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

CO039_MOUSE
NC score	0.062796 (rank : 1267)	θ value	0.47712 (rank : 1246)
Query Neighborhood Hits	1959	Target Neighborhood Hits	445	Shared Neighborhood Hits	229
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

CD4_HUMAN
NC score	0.062663 (rank : 1268)	θ value	θ > 10 (rank : 1976)
Query Neighborhood Hits	1959	Target Neighborhood Hits	122	Shared Neighborhood Hits	59
SwissProt Accessions	P01730, Q4ZGK2, Q5U066	Gene names	CD4
Domain Architecture
Description	T-cell surface glycoprotein CD4 precursor (T-cell surface antigen T4/Leu-3).

MINT_MOUSE
NC score	0.062494 (rank : 1269)	θ value	0.21417 (rank : 1163)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1514	Shared Neighborhood Hits	433
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

SAPS1_HUMAN
NC score	0.062455 (rank : 1270)	θ value	0.000602161 (rank : 895)
Query Neighborhood Hits	1959	Target Neighborhood Hits	704	Shared Neighborhood Hits	330
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

ANKF1_HUMAN
NC score	0.062380 (rank : 1271)	θ value	θ > 10 (rank : 1966)
Query Neighborhood Hits	1959	Target Neighborhood Hits	126	Shared Neighborhood Hits	50
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

CSF3R_MOUSE
NC score	0.062370 (rank : 1272)	θ value	θ > 10 (rank : 1993)
Query Neighborhood Hits	1959	Target Neighborhood Hits	104	Shared Neighborhood Hits	58
SwissProt Accessions	P40223	Gene names	Csf3r, Csfgr
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

CIC_HUMAN
NC score	0.062310 (rank : 1273)	θ value	0.00102713 (rank : 914)
Query Neighborhood Hits	1959	Target Neighborhood Hits	992	Shared Neighborhood Hits	395
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

YLPM1_HUMAN
NC score	0.061640 (rank : 1274)	θ value	8.99809 (rank : 1954)
Query Neighborhood Hits	1959	Target Neighborhood Hits	670	Shared Neighborhood Hits	285
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

DGKQ_HUMAN
NC score	0.061321 (rank : 1275)	θ value	θ > 10 (rank : 2003)
Query Neighborhood Hits	1959	Target Neighborhood Hits	131	Shared Neighborhood Hits	43
SwissProt Accessions	P52824	Gene names	DGKQ, DAGK4
Domain Architecture
Description	Diacylglycerol kinase theta (EC 2.7.1.107) (Diglyceride kinase theta) (DGK-theta) (DAG kinase theta).

CJ078_MOUSE
NC score	0.061226 (rank : 1276)	θ value	2.36792 (rank : 1527)
Query Neighborhood Hits	1959	Target Neighborhood Hits	559	Shared Neighborhood Hits	214
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

TENX_HUMAN
NC score	0.061122 (rank : 1277)	θ value	θ > 10 (rank : 2104)
Query Neighborhood Hits	1959	Target Neighborhood Hits	789	Shared Neighborhood Hits	190
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

NCOR2_HUMAN
NC score	0.061082 (rank : 1278)	θ value	0.0148317 (rank : 1011)
Query Neighborhood Hits	1959	Target Neighborhood Hits	870	Shared Neighborhood Hits	287
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

MADCA_HUMAN
NC score	0.061054 (rank : 1279)	θ value	1.81305 (rank : 1499)
Query Neighborhood Hits	1959	Target Neighborhood Hits	221	Shared Neighborhood Hits	125
SwissProt Accessions	Q13477, O60222, O75867	Gene names	MADCAM1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (hMAdCAM-1).

SET1A_HUMAN
NC score	0.060907 (rank : 1280)	θ value	0.0563607 (rank : 1079)
Query Neighborhood Hits	1959	Target Neighborhood Hits	690	Shared Neighborhood Hits	245
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

LAD1_HUMAN
NC score	0.060786 (rank : 1281)	θ value	0.813845 (rank : 1333)
Query Neighborhood Hits	1959	Target Neighborhood Hits	441	Shared Neighborhood Hits	174
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

SIGIR_MOUSE
NC score	0.060629 (rank : 1282)	θ value	4.03905 (rank : 1693)
Query Neighborhood Hits	1959	Target Neighborhood Hits	95	Shared Neighborhood Hits	61
SwissProt Accessions	Q9JLZ8, Q52L48	Gene names	Sigirr, Tir8
Domain Architecture	No domain graphic available
Description	Single Ig IL-1-related receptor (Single Ig IL-1R-related molecule) (Single immunoglobulin domain-containing IL1R-related protein) (Toll/interleukin-1 receptor 8) (TIR8).

MAP1A_HUMAN
NC score	0.060390 (rank : 1283)	θ value	0.00509761 (rank : 973)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1626	Shared Neighborhood Hits	398
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MLL2_HUMAN
NC score	0.060174 (rank : 1284)	θ value	0.163984 (rank : 1136)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1788	Shared Neighborhood Hits	475
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

I12R1_HUMAN
NC score	0.060101 (rank : 1285)	θ value	θ > 10 (rank : 2025)
Query Neighborhood Hits	1959	Target Neighborhood Hits	78	Shared Neighborhood Hits	49
SwissProt Accessions	P42701	Gene names	IL12RB1, IL12R, IL12RB
Domain Architecture
Description	Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) (IL- 12RB1) (CD212 antigen).

CHIO_MOUSE
NC score	0.059873 (rank : 1286)	θ value	θ > 10 (rank : 1985)
Query Neighborhood Hits	1959	Target Neighborhood Hits	130	Shared Neighborhood Hits	38
SwissProt Accessions	Q80XD1, Q9D9W2, Q9ER57	Gene names	Chn2, Arhgap3, Bch
Domain Architecture	No domain graphic available
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

FPRP_MOUSE
NC score	0.059730 (rank : 1287)	θ value	θ > 10 (rank : 2016)
Query Neighborhood Hits	1959	Target Neighborhood Hits	116	Shared Neighborhood Hits	66
SwissProt Accessions	Q9WV91	Gene names	Ptgfrn, Fprp
Domain Architecture
Description	Prostaglandin F2 receptor negative regulator precursor (Prostaglandin F2-alpha receptor regulatory protein) (Prostaglandin F2-alpha receptor-associated protein) (CD315 antigen).

RP1L1_HUMAN
NC score	0.059684 (rank : 1288)	θ value	0.0193708 (rank : 1022)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1072	Shared Neighborhood Hits	285
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

LR37A_HUMAN
NC score	0.058956 (rank : 1289)	θ value	0.279714 (rank : 1185)
Query Neighborhood Hits	1959	Target Neighborhood Hits	720	Shared Neighborhood Hits	270
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

ATN1_HUMAN
NC score	0.058838 (rank : 1290)	θ value	8.99809 (rank : 1867)
Query Neighborhood Hits	1959	Target Neighborhood Hits	676	Shared Neighborhood Hits	237
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

AMGO2_HUMAN
NC score	0.058697 (rank : 1291)	θ value	θ > 10 (rank : 1964)
Query Neighborhood Hits	1959	Target Neighborhood Hits	357	Shared Neighborhood Hits	135
SwissProt Accessions	Q86SJ2, Q7Z4A0, Q96CN8	Gene names	AMIGO2, ALI1
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 2 precursor (AMIGO-2) (Alivin-1) (Differentially expressed in gastric adenocarcinomas) (DEGA).

ENAH_MOUSE
NC score	0.058671 (rank : 1292)	θ value	1.38821 (rank : 1429)
Query Neighborhood Hits	1959	Target Neighborhood Hits	919	Shared Neighborhood Hits	286
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

YLPM1_MOUSE
NC score	0.058529 (rank : 1293)	θ value	0.00869519 (rank : 998)
Query Neighborhood Hits	1959	Target Neighborhood Hits	505	Shared Neighborhood Hits	218
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

RASA1_HUMAN
NC score	0.058431 (rank : 1294)	θ value	θ > 10 (rank : 2080)
Query Neighborhood Hits	1959	Target Neighborhood Hits	258	Shared Neighborhood Hits	75
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

RASF1_HUMAN
NC score	0.058099 (rank : 1295)	θ value	θ > 10 (rank : 2081)
Query Neighborhood Hits	1959	Target Neighborhood Hits	62	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NS23, O14571, O60539, O60710, Q9HB04, Q9HB18, Q9NS22, Q9UND4, Q9UND5	Gene names	RASSF1, RDA32
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 1.

MOX2R_HUMAN
NC score	0.057961 (rank : 1296)	θ value	θ > 10 (rank : 2051)
Query Neighborhood Hits	1959	Target Neighborhood Hits	51	Shared Neighborhood Hits	42
SwissProt Accessions	Q8TD46, Q8TD44, Q8TD45, Q8TD52	Gene names	CD200R1, CD200R, CRTR2, MOX2R, OX2R
Domain Architecture	No domain graphic available
Description	Cell surface glycoprotein OX2 receptor precursor (CD200 cell surface glycoprotein receptor).

SFPQ_HUMAN
NC score	0.057703 (rank : 1297)	θ value	0.163984 (rank : 1145)
Query Neighborhood Hits	1959	Target Neighborhood Hits	986	Shared Neighborhood Hits	274
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

SH21A_MOUSE
NC score	0.057694 (rank : 1298)	θ value	θ > 10 (rank : 2086)
Query Neighborhood Hits	1959	Target Neighborhood Hits	89	Shared Neighborhood Hits	43
SwissProt Accessions	O88890, Q9QWV6	Gene names	Sh2d1a, Xlp
Domain Architecture
Description	SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP).

SH21B_HUMAN
NC score	0.057632 (rank : 1299)	θ value	θ > 10 (rank : 2087)
Query Neighborhood Hits	1959	Target Neighborhood Hits	101	Shared Neighborhood Hits	44
SwissProt Accessions	O14796, Q5T0L1, Q8NI18, Q969K9	Gene names	SH2D1B, EAT2
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

CBP_MOUSE
NC score	0.057456 (rank : 1300)	θ value	1.81305 (rank : 1472)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1051	Shared Neighborhood Hits	403
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

BTNL2_HUMAN
NC score	0.057309 (rank : 1301)	θ value	θ > 10 (rank : 1971)
Query Neighborhood Hits	1959	Target Neighborhood Hits	164	Shared Neighborhood Hits	100
SwissProt Accessions	Q9UIR0, O98261, Q5JYF9, Q5RIF8, Q5SP08, Q5SP09, Q5SRW3, Q5SRW4, Q5SU36, Q95HK0	Gene names	BTNL2
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 2 precursor (BTL-II).

MLL3_HUMAN
NC score	0.057303 (rank : 1302)	θ value	0.0330416 (rank : 1038)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1644	Shared Neighborhood Hits	476
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MAP4_HUMAN
NC score	0.056901 (rank : 1303)	θ value	4.03905 (rank : 1668)
Query Neighborhood Hits	1959	Target Neighborhood Hits	428	Shared Neighborhood Hits	187
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

K1802_MOUSE
NC score	0.056845 (rank : 1304)	θ value	0.000602161 (rank : 889)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1596	Shared Neighborhood Hits	449
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MAP4_MOUSE
NC score	0.056829 (rank : 1305)	θ value	4.03905 (rank : 1669)
Query Neighborhood Hits	1959	Target Neighborhood Hits	409	Shared Neighborhood Hits	184
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

TCOF_MOUSE
NC score	0.056684 (rank : 1306)	θ value	4.03905 (rank : 1697)
Query Neighborhood Hits	1959	Target Neighborhood Hits	471	Shared Neighborhood Hits	178
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

HCFC1_MOUSE
NC score	0.056609 (rank : 1307)	θ value	0.813845 (rank : 1330)
Query Neighborhood Hits	1959	Target Neighborhood Hits	348	Shared Neighborhood Hits	148
SwissProt Accessions	Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2	Gene names	Hcfc1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

SIRB1_HUMAN
NC score	0.056445 (rank : 1308)	θ value	θ > 10 (rank : 2091)
Query Neighborhood Hits	1959	Target Neighborhood Hits	422	Shared Neighborhood Hits	98
SwissProt Accessions	O00241, Q5TFR0, Q8TB12, Q9H1U5, Q9Y4V0	Gene names	SIRPB1
Domain Architecture
Description	Signal-regulatory protein beta-1 precursor (SIRP-beta-1) (CD172b antigen).

FCRLA_MOUSE
NC score	0.056234 (rank : 1309)	θ value	0.62314 (rank : 1290)
Query Neighborhood Hits	1959	Target Neighborhood Hits	110	Shared Neighborhood Hits	62
SwissProt Accessions	Q920A9, Q3T9Q2, Q8K3U9, Q8VHP5	Gene names	Fcrla, Fcrl, Fcrl1, Fcrlm1, Fcrx, Freb
Domain Architecture	No domain graphic available
Description	Fc receptor-like and mucin-like 1 precursor (Fc receptor-like A) (Fc receptor homolog expressed in B-cells) (Fc receptor-related protein X) (FcRX) (Fc receptor-like protein).

SPR1A_MOUSE
NC score	0.056224 (rank : 1310)	θ value	0.00665767 (rank : 987)
Query Neighborhood Hits	1959	Target Neighborhood Hits	343	Shared Neighborhood Hits	155
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

BCL9_HUMAN
NC score	0.056173 (rank : 1311)	θ value	1.06291 (rank : 1362)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1008	Shared Neighborhood Hits	374
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

RAPH1_HUMAN
NC score	0.056104 (rank : 1312)	θ value	0.365318 (rank : 1231)
Query Neighborhood Hits	1959	Target Neighborhood Hits	593	Shared Neighborhood Hits	266
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

SYN1_HUMAN
NC score	0.055901 (rank : 1313)	θ value	0.0736092 (rank : 1097)
Query Neighborhood Hits	1959	Target Neighborhood Hits	419	Shared Neighborhood Hits	207
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

A1BG_HUMAN
NC score	0.055801 (rank : 1314)	θ value	0.163984 (rank : 1133)
Query Neighborhood Hits	1959	Target Neighborhood Hits	94	Shared Neighborhood Hits	44
SwissProt Accessions	P04217, Q8IYJ6, Q96P39	Gene names	A1BG
Domain Architecture
Description	Alpha-1B-glycoprotein precursor (Alpha-1-B glycoprotein).

DGKK_HUMAN
NC score	0.055329 (rank : 1315)	θ value	3.0926 (rank : 1584)
Query Neighborhood Hits	1959	Target Neighborhood Hits	378	Shared Neighborhood Hits	177
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

JPH2_HUMAN
NC score	0.055227 (rank : 1316)	θ value	0.125558 (rank : 1123)
Query Neighborhood Hits	1959	Target Neighborhood Hits	639	Shared Neighborhood Hits	297
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

PCQAP_HUMAN
NC score	0.055194 (rank : 1317)	θ value	4.03905 (rank : 1676)
Query Neighborhood Hits	1959	Target Neighborhood Hits	549	Shared Neighborhood Hits	178
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

RERE_HUMAN
NC score	0.054964 (rank : 1318)	θ value	0.163984 (rank : 1143)
Query Neighborhood Hits	1959	Target Neighborhood Hits	779	Shared Neighborhood Hits	290
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

CBP_HUMAN
NC score	0.054957 (rank : 1319)	θ value	0.813845 (rank : 1314)
Query Neighborhood Hits	1959	Target Neighborhood Hits	941	Shared Neighborhood Hits	355
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

RIMB2_HUMAN
NC score	0.054934 (rank : 1320)	θ value	θ > 10 (rank : 2083)
Query Neighborhood Hits	1959	Target Neighborhood Hits	263	Shared Neighborhood Hits	89
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

SPRR3_HUMAN
NC score	0.054455 (rank : 1321)	θ value	0.0736092 (rank : 1096)
Query Neighborhood Hits	1959	Target Neighborhood Hits	102	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UBC9, O75597, Q4ZGI7, Q5T525, Q8NET7, Q9UDG3	Gene names	SPRR3, SPRC
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta) (Esophagin) (22 kDa pancornulin).

FCG2B_HUMAN
NC score	0.054148 (rank : 1322)	θ value	θ > 10 (rank : 2007)
Query Neighborhood Hits	1959	Target Neighborhood Hits	116	Shared Neighborhood Hits	76
SwissProt Accessions	P31994, O95649, Q53X85, Q5VXA9, Q8NIA1	Gene names	FCGR2B, CD32, FCG2, IGFR2
Domain Architecture
Description	Low affinity immunoglobulin gamma Fc region receptor II-b precursor (Fc-gamma RII-b) (FcRII-b) (IgG Fc receptor II-b) (Fc-gamma-RIIb) (CD32 antigen) (CDw32).

MARCS_HUMAN
NC score	0.053880 (rank : 1323)	θ value	1.38821 (rank : 1444)
Query Neighborhood Hits	1959	Target Neighborhood Hits	204	Shared Neighborhood Hits	99
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

FCG2C_HUMAN
NC score	0.053817 (rank : 1324)	θ value	θ > 10 (rank : 2008)
Query Neighborhood Hits	1959	Target Neighborhood Hits	118	Shared Neighborhood Hits	77
SwissProt Accessions	P31995, O00523, O00524, O00525	Gene names	FCGR2C, CD32, FCG2, IGFR2
Domain Architecture
Description	Low affinity immunoglobulin gamma Fc region receptor II-c precursor (Fc-gamma RII-c) (FcRII-c) (IgG Fc receptor II-c) (Fc-gamma-RIIc) (CD32 antigen) (CDw32).

SYN1_MOUSE
NC score	0.053696 (rank : 1325)	θ value	0.0113563 (rank : 1006)
Query Neighborhood Hits	1959	Target Neighborhood Hits	363	Shared Neighborhood Hits	187
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

RTP3_MOUSE
NC score	0.053447 (rank : 1326)	θ value	0.0330416 (rank : 1045)
Query Neighborhood Hits	1959	Target Neighborhood Hits	374	Shared Neighborhood Hits	171
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

TAU_MOUSE
NC score	0.053263 (rank : 1327)	θ value	0.47712 (rank : 1272)
Query Neighborhood Hits	1959	Target Neighborhood Hits	502	Shared Neighborhood Hits	225
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

ACINU_HUMAN
NC score	0.053028 (rank : 1328)	θ value	4.03905 (rank : 1633)
Query Neighborhood Hits	1959	Target Neighborhood Hits	828	Shared Neighborhood Hits	199
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

MISS_MOUSE
NC score	0.052763 (rank : 1329)	θ value	0.125558 (rank : 1126)
Query Neighborhood Hits	1959	Target Neighborhood Hits	444	Shared Neighborhood Hits	207
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

DAPP1_HUMAN
NC score	0.052582 (rank : 1330)	θ value	θ > 10 (rank : 1997)
Query Neighborhood Hits	1959	Target Neighborhood Hits	227	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

PSL1_HUMAN
NC score	0.052533 (rank : 1331)	θ value	0.0330416 (rank : 1044)
Query Neighborhood Hits	1959	Target Neighborhood Hits	650	Shared Neighborhood Hits	280
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

SH21A_HUMAN
NC score	0.052472 (rank : 1332)	θ value	θ > 10 (rank : 2085)
Query Neighborhood Hits	1959	Target Neighborhood Hits	89	Shared Neighborhood Hits	42
SwissProt Accessions	O60880, O95383, O95384, O95385, O95386, Q9UNR0	Gene names	SH2D1A, DSHP, SAP
Domain Architecture
Description	SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP) (Duncan disease SH2-protein).

GGN_MOUSE
NC score	0.052357 (rank : 1333)	θ value	θ > 10 (rank : 2017)
Query Neighborhood Hits	1959	Target Neighborhood Hits	311	Shared Neighborhood Hits	160
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

RERE_MOUSE
NC score	0.052356 (rank : 1334)	θ value	0.62314 (rank : 1304)
Query Neighborhood Hits	1959	Target Neighborhood Hits	785	Shared Neighborhood Hits	294
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

TP53B_MOUSE
NC score	0.052305 (rank : 1335)	θ value	0.21417 (rank : 1171)
Query Neighborhood Hits	1959	Target Neighborhood Hits	644	Shared Neighborhood Hits	217
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

JAML1_HUMAN
NC score	0.052089 (rank : 1336)	θ value	θ > 10 (rank : 2043)
Query Neighborhood Hits	1959	Target Neighborhood Hits	108	Shared Neighborhood Hits	55
SwissProt Accessions	Q86YT9, Q5DTC6, Q7Z499, Q8N9I7, Q8NF70	Gene names	AMICA1, JAML
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule-like precursor (Dendritic cell-specific protein CREA7-1) (Adhesion molecule interacting with CXADR antigen 1).

MARCS_MOUSE
NC score	0.052058 (rank : 1337)	θ value	θ > 10 (rank : 2048)
Query Neighborhood Hits	1959	Target Neighborhood Hits	227	Shared Neighborhood Hits	98
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

TARA_MOUSE
NC score	0.052038 (rank : 1338)	θ value	0.47712 (rank : 1271)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1133	Shared Neighborhood Hits	325
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

SFRIP_HUMAN
NC score	0.051980 (rank : 1339)	θ value	0.125558 (rank : 1130)
Query Neighborhood Hits	1959	Target Neighborhood Hits	530	Shared Neighborhood Hits	161
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

NOLC1_HUMAN
NC score	0.051969 (rank : 1340)	θ value	θ > 10 (rank : 2055)
Query Neighborhood Hits	1959	Target Neighborhood Hits	452	Shared Neighborhood Hits	150
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

TCOF_HUMAN
NC score	0.051887 (rank : 1341)	θ value	1.06291 (rank : 1412)
Query Neighborhood Hits	1959	Target Neighborhood Hits	543	Shared Neighborhood Hits	190
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

CSKI1_HUMAN
NC score	0.051513 (rank : 1342)	θ value	0.125558 (rank : 1118)
Query Neighborhood Hits	1959	Target Neighborhood Hits	997	Shared Neighborhood Hits	362
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

ASPP1_MOUSE
NC score	0.051409 (rank : 1343)	θ value	0.62314 (rank : 1285)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1244	Shared Neighborhood Hits	341
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

DAPP1_MOUSE
NC score	0.051274 (rank : 1344)	θ value	θ > 10 (rank : 1998)
Query Neighborhood Hits	1959	Target Neighborhood Hits	225	Shared Neighborhood Hits	69
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

MLL3_MOUSE
NC score	0.051238 (rank : 1345)	θ value	1.38821 (rank : 1447)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1399	Shared Neighborhood Hits	382
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

RIMB1_HUMAN
NC score	0.051206 (rank : 1346)	θ value	1.81305 (rank : 1510)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1479	Shared Neighborhood Hits	341
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

FCRLA_HUMAN
NC score	0.051011 (rank : 1347)	θ value	θ > 10 (rank : 2013)
Query Neighborhood Hits	1959	Target Neighborhood Hits	135	Shared Neighborhood Hits	76
SwissProt Accessions	Q7L513, Q5VXA1, Q5VXA2, Q5VXA3, Q5VXB0, Q8NEW4, Q8WXH3, Q96PC6, Q96PJ0, Q96PJ1, Q96PJ2, Q96PJ4, Q9BR57	Gene names	FCRLA, FCRL, FCRL1, FCRLM1, FCRX, FREB
Domain Architecture	No domain graphic available
Description	Fc receptor-like and mucin-like 1 precursor (Fc receptor-like A) (Fc receptor homolog expressed in B-cells) (Fc receptor-related protein X) (FcRX) (Fc receptor-like protein).

CT075_MOUSE
NC score	0.050929 (rank : 1348)	θ value	θ > 10 (rank : 1995)
Query Neighborhood Hits	1959	Target Neighborhood Hits	358	Shared Neighborhood Hits	106
SwissProt Accessions	P59383	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf75 homolog precursor.

MAP1B_HUMAN
NC score	0.050610 (rank : 1349)	θ value	0.00134147 (rank : 927)
Query Neighborhood Hits	1959	Target Neighborhood Hits	903	Shared Neighborhood Hits	204
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

EP300_HUMAN
NC score	0.050534 (rank : 1350)	θ value	0.365318 (rank : 1208)
Query Neighborhood Hits	1959	Target Neighborhood Hits	821	Shared Neighborhood Hits	327
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

IWS1_MOUSE
NC score	0.050522 (rank : 1351)	θ value	0.0113563 (rank : 1002)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1258	Shared Neighborhood Hits	333
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

PRAX_HUMAN
NC score	0.050369 (rank : 1352)	θ value	0.125558 (rank : 1127)
Query Neighborhood Hits	1959	Target Neighborhood Hits	215	Shared Neighborhood Hits	94
SwissProt Accessions	Q9BXM0, Q9BXL9, Q9HCF2	Gene names	PRX, KIAA1620
Domain Architecture
Description	Periaxin.

IWS1_HUMAN
NC score	0.050340 (rank : 1353)	θ value	0.365318 (rank : 1216)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1241	Shared Neighborhood Hits	301
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

NIPBL_HUMAN
NC score	0.050335 (rank : 1354)	θ value	2.36792 (rank : 1548)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1311	Shared Neighborhood Hits	312
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

CK024_MOUSE
NC score	0.050331 (rank : 1355)	θ value	0.813845 (rank : 1317)
Query Neighborhood Hits	1959	Target Neighborhood Hits	307	Shared Neighborhood Hits	140
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

SFPQ_MOUSE
NC score	0.050174 (rank : 1356)	θ value	0.365318 (rank : 1236)
Query Neighborhood Hits	1959	Target Neighborhood Hits	958	Shared Neighborhood Hits	271
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

CSKI1_MOUSE
NC score	0.050120 (rank : 1357)	θ value	1.81305 (rank : 1476)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1031	Shared Neighborhood Hits	376
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

TENA_HUMAN
NC score	0.050007 (rank : 1358)	θ value	θ > 10 (rank : 2101)
Query Neighborhood Hits	1959	Target Neighborhood Hits	631	Shared Neighborhood Hits	136
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

CABIN_HUMAN
NC score	0.049879 (rank : 1359)	θ value	1.81305 (rank : 1471)
Query Neighborhood Hits	1959	Target Neighborhood Hits	490	Shared Neighborhood Hits	232
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

PCQAP_MOUSE
NC score	0.049869 (rank : 1360)	θ value	3.0926 (rank : 1607)
Query Neighborhood Hits	1959	Target Neighborhood Hits	506	Shared Neighborhood Hits	166
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

MUC2_HUMAN
NC score	0.049854 (rank : 1361)	θ value	0.00665767 (rank : 985)
Query Neighborhood Hits	1959	Target Neighborhood Hits	906	Shared Neighborhood Hits	290
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

SYNJ1_MOUSE
NC score	0.049848 (rank : 1362)	θ value	1.38821 (rank : 1459)
Query Neighborhood Hits	1959	Target Neighborhood Hits	516	Shared Neighborhood Hits	256
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

MINT_HUMAN
NC score	0.049841 (rank : 1363)	θ value	0.365318 (rank : 1225)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1291	Shared Neighborhood Hits	354
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

TMM25_MOUSE
NC score	0.049776 (rank : 1364)	θ value	6.88961 (rank : 1854)
Query Neighborhood Hits	1959	Target Neighborhood Hits	46	Shared Neighborhood Hits	44
SwissProt Accessions	Q9DCF1, Q3TMP3, Q6PAK7	Gene names	Tmem25
Domain Architecture	No domain graphic available
Description	Transmembrane protein 25 precursor.

K1543_HUMAN
NC score	0.049574 (rank : 1365)	θ value	0.62314 (rank : 1297)
Query Neighborhood Hits	1959	Target Neighborhood Hits	435	Shared Neighborhood Hits	205
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

K1683_HUMAN
NC score	0.049491 (rank : 1366)	θ value	3.0926 (rank : 1598)
Query Neighborhood Hits	1959	Target Neighborhood Hits	240	Shared Neighborhood Hits	116
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

SNPC4_HUMAN
NC score	0.049446 (rank : 1367)	θ value	3.0926 (rank : 1619)
Query Neighborhood Hits	1959	Target Neighborhood Hits	589	Shared Neighborhood Hits	263
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

MILK1_MOUSE
NC score	0.049434 (rank : 1368)	θ value	0.00175202 (rank : 935)
Query Neighborhood Hits	1959	Target Neighborhood Hits	788	Shared Neighborhood Hits	324
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

CJ012_HUMAN
NC score	0.049415 (rank : 1369)	θ value	4.03905 (rank : 1645)
Query Neighborhood Hits	1959	Target Neighborhood Hits	467	Shared Neighborhood Hits	163
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

ARI1B_HUMAN
NC score	0.049140 (rank : 1370)	θ value	0.00869519 (rank : 991)
Query Neighborhood Hits	1959	Target Neighborhood Hits	567	Shared Neighborhood Hits	220
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

GGN_HUMAN
NC score	0.048930 (rank : 1371)	θ value	1.81305 (rank : 1488)
Query Neighborhood Hits	1959	Target Neighborhood Hits	269	Shared Neighborhood Hits	140
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

AKAP2_MOUSE
NC score	0.048828 (rank : 1372)	θ value	0.000786445 (rank : 896)
Query Neighborhood Hits	1959	Target Neighborhood Hits	385	Shared Neighborhood Hits	124
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

HCFC1_HUMAN
NC score	0.048712 (rank : 1373)	θ value	5.27518 (rank : 1742)
Query Neighborhood Hits	1959	Target Neighborhood Hits	331	Shared Neighborhood Hits	143
SwissProt Accessions	P51610, Q6P4G5	Gene names	HCFC1, HCF1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) (VP16 accessory protein) (VCAF) (CFF) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C- terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

BAG3_MOUSE
NC score	0.048690 (rank : 1374)	θ value	1.81305 (rank : 1468)
Query Neighborhood Hits	1959	Target Neighborhood Hits	513	Shared Neighborhood Hits	243
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

CO039_HUMAN
NC score	0.048583 (rank : 1375)	θ value	0.813845 (rank : 1320)
Query Neighborhood Hits	1959	Target Neighborhood Hits	264	Shared Neighborhood Hits	143
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

SC24C_HUMAN
NC score	0.048381 (rank : 1376)	θ value	0.163984 (rank : 1144)
Query Neighborhood Hits	1959	Target Neighborhood Hits	662	Shared Neighborhood Hits	270
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

PO121_HUMAN
NC score	0.048366 (rank : 1377)	θ value	1.38821 (rank : 1453)
Query Neighborhood Hits	1959	Target Neighborhood Hits	344	Shared Neighborhood Hits	144
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

MAP1B_MOUSE
NC score	0.048274 (rank : 1378)	θ value	0.0736092 (rank : 1091)
Query Neighborhood Hits	1959	Target Neighborhood Hits	977	Shared Neighborhood Hits	226
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

TAU_HUMAN
NC score	0.048124 (rank : 1379)	θ value	0.813845 (rank : 1352)
Query Neighborhood Hits	1959	Target Neighborhood Hits	448	Shared Neighborhood Hits	198
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

AMGO3_HUMAN
NC score	0.047706 (rank : 1380)	θ value	0.62314 (rank : 1283)
Query Neighborhood Hits	1959	Target Neighborhood Hits	276	Shared Neighborhood Hits	84
SwissProt Accessions	Q86WK7, Q96JH6	Gene names	AMIGO3, ALI3, KIAA1851
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 3 precursor (AMIGO-3) (Alivin-3).

LCP2_MOUSE
NC score	0.047582 (rank : 1381)	θ value	0.813845 (rank : 1334)
Query Neighborhood Hits	1959	Target Neighborhood Hits	177	Shared Neighborhood Hits	83
SwissProt Accessions	Q60787	Gene names	Lcp2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

EFS_HUMAN
NC score	0.047075 (rank : 1382)	θ value	0.0148317 (rank : 1008)
Query Neighborhood Hits	1959	Target Neighborhood Hits	348	Shared Neighborhood Hits	146
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

PI5PA_MOUSE
NC score	0.046996 (rank : 1383)	θ value	0.62314 (rank : 1303)
Query Neighborhood Hits	1959	Target Neighborhood Hits	331	Shared Neighborhood Hits	189
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

TROAP_HUMAN
NC score	0.046300 (rank : 1384)	θ value	0.0563607 (rank : 1081)
Query Neighborhood Hits	1959	Target Neighborhood Hits	258	Shared Neighborhood Hits	134
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

DIDO1_HUMAN
NC score	0.046270 (rank : 1385)	θ value	0.0431538 (rank : 1056)
Query Neighborhood Hits	1959	Target Neighborhood Hits	960	Shared Neighborhood Hits	310
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

ACINU_MOUSE
NC score	0.046238 (rank : 1386)	θ value	0.0330416 (rank : 1035)
Query Neighborhood Hits	1959	Target Neighborhood Hits	712	Shared Neighborhood Hits	187
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

ARI1A_HUMAN
NC score	0.046231 (rank : 1387)	θ value	0.279714 (rank : 1176)
Query Neighborhood Hits	1959	Target Neighborhood Hits	787	Shared Neighborhood Hits	269
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

ANK2_HUMAN
NC score	0.046165 (rank : 1388)	θ value	0.0961366 (rank : 1099)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1615	Shared Neighborhood Hits	451
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

PHLB1_HUMAN
NC score	0.046073 (rank : 1389)	θ value	0.0563607 (rank : 1075)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1038	Shared Neighborhood Hits	269
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

I11RA_HUMAN
NC score	0.046059 (rank : 1390)	θ value	5.27518 (rank : 1747)
Query Neighborhood Hits	1959	Target Neighborhood Hits	138	Shared Neighborhood Hits	63
SwissProt Accessions	Q14626, Q16542, Q7KYJ7	Gene names	IL11RA
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha chain precursor (IL-11R-alpha) (IL- 11RA).

TMM25_HUMAN
NC score	0.045691 (rank : 1391)	θ value	6.88961 (rank : 1853)
Query Neighborhood Hits	1959	Target Neighborhood Hits	43	Shared Neighborhood Hits	40
SwissProt Accessions	Q86YD3, Q6UW89, Q86UA7, Q96KA6, Q96MW9	Gene names	TMEM25
Domain Architecture	No domain graphic available
Description	Transmembrane protein 25 precursor.

ENAH_HUMAN
NC score	0.045645 (rank : 1392)	θ value	4.03905 (rank : 1654)
Query Neighborhood Hits	1959	Target Neighborhood Hits	784	Shared Neighborhood Hits	210
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

MTSS1_HUMAN
NC score	0.045531 (rank : 1393)	θ value	0.00869519 (rank : 994)
Query Neighborhood Hits	1959	Target Neighborhood Hits	504	Shared Neighborhood Hits	175
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

CNOT3_HUMAN
NC score	0.045530 (rank : 1394)	θ value	0.21417 (rank : 1152)
Query Neighborhood Hits	1959	Target Neighborhood Hits	425	Shared Neighborhood Hits	131
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

PRAX_MOUSE
NC score	0.045487 (rank : 1395)	θ value	1.81305 (rank : 1508)
Query Neighborhood Hits	1959	Target Neighborhood Hits	199	Shared Neighborhood Hits	95
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

NCOR2_MOUSE
NC score	0.045219 (rank : 1396)	θ value	0.21417 (rank : 1164)
Query Neighborhood Hits	1959	Target Neighborhood Hits	790	Shared Neighborhood Hits	231
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

CIC_MOUSE
NC score	0.045137 (rank : 1397)	θ value	8.99809 (rank : 1883)
Query Neighborhood Hits	1959	Target Neighborhood Hits	742	Shared Neighborhood Hits	305
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

AMGO3_MOUSE
NC score	0.044936 (rank : 1398)	θ value	1.38821 (rank : 1423)
Query Neighborhood Hits	1959	Target Neighborhood Hits	276	Shared Neighborhood Hits	80
SwissProt Accessions	Q8C2S7, Q6ZPH1, Q8CEB3	Gene names	Amigo3, Ali3, Kiaa1851
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 3 precursor (AMIGO-3) (Alivin-3).

NPBL_MOUSE
NC score	0.044924 (rank : 1399)	θ value	1.38821 (rank : 1450)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1041	Shared Neighborhood Hits	283
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

PO121_MOUSE
NC score	0.044729 (rank : 1400)	θ value	8.99809 (rank : 1928)
Query Neighborhood Hits	1959	Target Neighborhood Hits	345	Shared Neighborhood Hits	143
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

SPR1A_HUMAN
NC score	0.044600 (rank : 1401)	θ value	0.0736092 (rank : 1095)
Query Neighborhood Hits	1959	Target Neighborhood Hits	136	Shared Neighborhood Hits	58
SwissProt Accessions	P35321, Q9UDG4	Gene names	SPRR1A
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein IA) (SPR-IA) (SPRK) (19 kDa pancornulin).

DOT1L_HUMAN
NC score	0.044448 (rank : 1402)	θ value	6.88961 (rank : 1815)
Query Neighborhood Hits	1959	Target Neighborhood Hits	660	Shared Neighborhood Hits	220
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

IGSF8_HUMAN
NC score	0.044279 (rank : 1403)	θ value	1.81305 (rank : 1492)
Query Neighborhood Hits	1959	Target Neighborhood Hits	88	Shared Neighborhood Hits	41
SwissProt Accessions	Q969P0, Q8NG09, Q96DP4, Q9BTG9	Gene names	IGSF8, CD81P3, EWI2, KCT4
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 8 precursor (CD81 partner 3) (Glu- Trp-Ile EWI motif-containing protein 2) (EWI-2) (Keratinocytes- associated transmembrane protein 4) (KCT-4) (LIR-D1) (CD316 antigen).

TM108_HUMAN
NC score	0.044258 (rank : 1404)	θ value	4.03905 (rank : 1700)
Query Neighborhood Hits	1959	Target Neighborhood Hits	166	Shared Neighborhood Hits	95
SwissProt Accessions	Q6UXF1, Q9BQH1, Q9BW81, Q9C0H3	Gene names	TMEM108, KIAA1690
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

APXL_HUMAN
NC score	0.044220 (rank : 1405)	θ value	1.06291 (rank : 1357)
Query Neighborhood Hits	1959	Target Neighborhood Hits	553	Shared Neighborhood Hits	179
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

K0310_HUMAN
NC score	0.044152 (rank : 1406)	θ value	3.0926 (rank : 1597)
Query Neighborhood Hits	1959	Target Neighborhood Hits	420	Shared Neighborhood Hits	201
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

BCAR1_HUMAN
NC score	0.043961 (rank : 1407)	θ value	0.125558 (rank : 1116)
Query Neighborhood Hits	1959	Target Neighborhood Hits	554	Shared Neighborhood Hits	222
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

SF01_HUMAN
NC score	0.043942 (rank : 1408)	θ value	1.06291 (rank : 1406)
Query Neighborhood Hits	1959	Target Neighborhood Hits	287	Shared Neighborhood Hits	133
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

CASC3_MOUSE
NC score	0.043868 (rank : 1409)	θ value	2.36792 (rank : 1526)
Query Neighborhood Hits	1959	Target Neighborhood Hits	333	Shared Neighborhood Hits	152
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

SYNPO_HUMAN
NC score	0.043619 (rank : 1410)	θ value	0.0148317 (rank : 1013)
Query Neighborhood Hits	1959	Target Neighborhood Hits	281	Shared Neighborhood Hits	144
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

PELP1_MOUSE
NC score	0.043499 (rank : 1411)	θ value	6.88961 (rank : 1842)
Query Neighborhood Hits	1959	Target Neighborhood Hits	709	Shared Neighborhood Hits	241
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

TB182_HUMAN
NC score	0.043216 (rank : 1412)	θ value	0.62314 (rank : 1308)
Query Neighborhood Hits	1959	Target Neighborhood Hits	414	Shared Neighborhood Hits	139
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

MKL1_MOUSE
NC score	0.043182 (rank : 1413)	θ value	1.38821 (rank : 1446)
Query Neighborhood Hits	1959	Target Neighborhood Hits	667	Shared Neighborhood Hits	272
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

SFR15_HUMAN
NC score	0.043036 (rank : 1414)	θ value	0.62314 (rank : 1306)
Query Neighborhood Hits	1959	Target Neighborhood Hits	368	Shared Neighborhood Hits	135
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

CSKI2_HUMAN
NC score	0.043004 (rank : 1415)	θ value	0.813845 (rank : 1322)
Query Neighborhood Hits	1959	Target Neighborhood Hits	747	Shared Neighborhood Hits	229
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

OBF1_HUMAN
NC score	0.042743 (rank : 1416)	θ value	0.21417 (rank : 1165)
Query Neighborhood Hits	1959	Target Neighborhood Hits	203	Shared Neighborhood Hits	117
SwissProt Accessions	Q16633, Q14983	Gene names	POU2AF1, OBF1
Domain Architecture	No domain graphic available
Description	POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (OCT-binding factor 1) (BOB-1) (OCA-B).

TAF3_MOUSE
NC score	0.042742 (rank : 1417)	θ value	0.47712 (rank : 1270)
Query Neighborhood Hits	1959	Target Neighborhood Hits	463	Shared Neighborhood Hits	122
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

DREB_HUMAN
NC score	0.042640 (rank : 1418)	θ value	0.0431538 (rank : 1057)
Query Neighborhood Hits	1959	Target Neighborhood Hits	450	Shared Neighborhood Hits	106
SwissProt Accessions	Q16643	Gene names	DBN1
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

MLL4_HUMAN
NC score	0.042497 (rank : 1419)	θ value	0.279714 (rank : 1187)
Query Neighborhood Hits	1959	Target Neighborhood Hits	722	Shared Neighborhood Hits	277
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

CG1_HUMAN
NC score	0.042356 (rank : 1420)	θ value	0.279714 (rank : 1178)
Query Neighborhood Hits	1959	Target Neighborhood Hits	222	Shared Neighborhood Hits	105
SwissProt Accessions	Q13495	Gene names	CXorf6, CG1
Domain Architecture	No domain graphic available
Description	CG1 protein (F18).

MUCDL_HUMAN
NC score	0.042240 (rank : 1421)	θ value	0.365318 (rank : 1227)
Query Neighborhood Hits	1959	Target Neighborhood Hits	777	Shared Neighborhood Hits	293
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

ZAR1_HUMAN
NC score	0.042169 (rank : 1422)	θ value	0.21417 (rank : 1172)
Query Neighborhood Hits	1959	Target Neighborhood Hits	163	Shared Neighborhood Hits	73
SwissProt Accessions	Q86SH2	Gene names	ZAR1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

SEPT9_HUMAN
NC score	0.042086 (rank : 1423)	θ value	0.0330416 (rank : 1046)
Query Neighborhood Hits	1959	Target Neighborhood Hits	706	Shared Neighborhood Hits	299
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

RBBP6_MOUSE
NC score	0.042014 (rank : 1424)	θ value	0.813845 (rank : 1346)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1014	Shared Neighborhood Hits	226
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

ENL_HUMAN
NC score	0.041853 (rank : 1425)	θ value	0.813845 (rank : 1323)
Query Neighborhood Hits	1959	Target Neighborhood Hits	305	Shared Neighborhood Hits	107
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

TULP4_HUMAN
NC score	0.041619 (rank : 1426)	θ value	0.00228821 (rank : 949)
Query Neighborhood Hits	1959	Target Neighborhood Hits	426	Shared Neighborhood Hits	147
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

NFRKB_MOUSE
NC score	0.041606 (rank : 1427)	θ value	0.0563607 (rank : 1074)
Query Neighborhood Hits	1959	Target Neighborhood Hits	393	Shared Neighborhood Hits	176
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

BAG3_HUMAN
NC score	0.041404 (rank : 1428)	θ value	1.06291 (rank : 1359)
Query Neighborhood Hits	1959	Target Neighborhood Hits	314	Shared Neighborhood Hits	159
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

SYNJ1_HUMAN
NC score	0.041282 (rank : 1429)	θ value	0.365318 (rank : 1238)
Query Neighborhood Hits	1959	Target Neighborhood Hits	498	Shared Neighborhood Hits	242
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

CSKI2_MOUSE
NC score	0.041235 (rank : 1430)	θ value	0.0113563 (rank : 1001)
Query Neighborhood Hits	1959	Target Neighborhood Hits	812	Shared Neighborhood Hits	249
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

PPRB_HUMAN
NC score	0.041221 (rank : 1431)	θ value	1.81305 (rank : 1507)
Query Neighborhood Hits	1959	Target Neighborhood Hits	311	Shared Neighborhood Hits	122
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

K1802_HUMAN
NC score	0.041205 (rank : 1432)	θ value	0.125558 (rank : 1124)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1378	Shared Neighborhood Hits	404
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

CCNK_MOUSE
NC score	0.041144 (rank : 1433)	θ value	1.06291 (rank : 1364)
Query Neighborhood Hits	1959	Target Neighborhood Hits	350	Shared Neighborhood Hits	155
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

GA2L2_MOUSE
NC score	0.041087 (rank : 1434)	θ value	0.47712 (rank : 1252)
Query Neighborhood Hits	1959	Target Neighborhood Hits	395	Shared Neighborhood Hits	200
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

EFS_MOUSE
NC score	0.041048 (rank : 1435)	θ value	8.99809 (rank : 1896)
Query Neighborhood Hits	1959	Target Neighborhood Hits	389	Shared Neighborhood Hits	159
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

SF3B1_MOUSE
NC score	0.040987 (rank : 1436)	θ value	0.813845 (rank : 1350)
Query Neighborhood Hits	1959	Target Neighborhood Hits	352	Shared Neighborhood Hits	152
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

LPP_HUMAN
NC score	0.040674 (rank : 1437)	θ value	0.47712 (rank : 1263)
Query Neighborhood Hits	1959	Target Neighborhood Hits	775	Shared Neighborhood Hits	286
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

CNTRB_MOUSE
NC score	0.040430 (rank : 1438)	θ value	0.813845 (rank : 1319)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1029	Shared Neighborhood Hits	188
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

TCRG1_HUMAN
NC score	0.040202 (rank : 1439)	θ value	6.88961 (rank : 1851)
Query Neighborhood Hits	1959	Target Neighborhood Hits	929	Shared Neighborhood Hits	218
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

SF3B1_HUMAN
NC score	0.040043 (rank : 1440)	θ value	0.813845 (rank : 1349)
Query Neighborhood Hits	1959	Target Neighborhood Hits	341	Shared Neighborhood Hits	148
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

PDZD2_HUMAN
NC score	0.040011 (rank : 1441)	θ value	0.0148317 (rank : 1012)
Query Neighborhood Hits	1959	Target Neighborhood Hits	772	Shared Neighborhood Hits	250
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

SHAN1_HUMAN
NC score	0.039915 (rank : 1442)	θ value	3.0926 (rank : 1614)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1041	Shared Neighborhood Hits	293
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

AL2S4_MOUSE
NC score	0.039807 (rank : 1443)	θ value	0.125558 (rank : 1114)
Query Neighborhood Hits	1959	Target Neighborhood Hits	193	Shared Neighborhood Hits	90
SwissProt Accessions	Q3V0J1, Q3TIS2	Gene names	Als2cr4
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein homolog.

BT1A1_MOUSE
NC score	0.039806 (rank : 1444)	θ value	1.81305 (rank : 1470)
Query Neighborhood Hits	1959	Target Neighborhood Hits	252	Shared Neighborhood Hits	105
SwissProt Accessions	Q62556, P97392, Q8K2H7, Q921K7	Gene names	Btn1a1, Btn
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

SPR1B_HUMAN
NC score	0.039706 (rank : 1445)	θ value	0.163984 (rank : 1147)
Query Neighborhood Hits	1959	Target Neighborhood Hits	102	Shared Neighborhood Hits	41
SwissProt Accessions	P22528, P22529, P22530, Q5T524	Gene names	SPRR1B
Domain Architecture	No domain graphic available
Description	Cornifin B (Small proline-rich protein IB) (SPR-IB) (14.9 kDa pancornulin).

TM108_MOUSE
NC score	0.039470 (rank : 1446)	θ value	0.47712 (rank : 1275)
Query Neighborhood Hits	1959	Target Neighborhood Hits	336	Shared Neighborhood Hits	158
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

WASF2_MOUSE
NC score	0.039361 (rank : 1447)	θ value	1.38821 (rank : 1462)
Query Neighborhood Hits	1959	Target Neighborhood Hits	315	Shared Neighborhood Hits	170
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

SFRS8_HUMAN
NC score	0.039139 (rank : 1448)	θ value	0.163984 (rank : 1146)
Query Neighborhood Hits	1959	Target Neighborhood Hits	166	Shared Neighborhood Hits	67
SwissProt Accessions	Q12872	Gene names	SFRS8, SWAP
Domain Architecture
Description	Splicing factor, arginine/serine-rich 8 (Suppressor of white apricot protein homolog).

SHC2_HUMAN
NC score	0.038883 (rank : 1449)	θ value	3.0926 (rank : 1615)
Query Neighborhood Hits	1959	Target Neighborhood Hits	170	Shared Neighborhood Hits	60
SwissProt Accessions	P98077, O60230, Q9NPL5, Q9UCX4	Gene names	SHC2, SCK, SHCB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck).

SHC1_HUMAN
NC score	0.038761 (rank : 1450)	θ value	2.36792 (rank : 1565)
Query Neighborhood Hits	1959	Target Neighborhood Hits	170	Shared Neighborhood Hits	63
SwissProt Accessions	P29353, O15290, Q8N4K5, Q96CL1	Gene names	SHC1, SHC, SHCA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

CEL_HUMAN
NC score	0.038749 (rank : 1451)	θ value	1.81305 (rank : 1473)
Query Neighborhood Hits	1959	Target Neighborhood Hits	896	Shared Neighborhood Hits	332
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

FMN2_HUMAN
NC score	0.038724 (rank : 1452)	θ value	1.06291 (rank : 1373)
Query Neighborhood Hits	1959	Target Neighborhood Hits	484	Shared Neighborhood Hits	182
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

ATX2L_HUMAN
NC score	0.038704 (rank : 1453)	θ value	6.88961 (rank : 1796)
Query Neighborhood Hits	1959	Target Neighborhood Hits	443	Shared Neighborhood Hits	199
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

TAF3_HUMAN
NC score	0.038703 (rank : 1454)	θ value	2.36792 (rank : 1568)
Query Neighborhood Hits	1959	Target Neighborhood Hits	568	Shared Neighborhood Hits	150
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

BCAR1_MOUSE
NC score	0.038593 (rank : 1455)	θ value	0.21417 (rank : 1150)
Query Neighborhood Hits	1959	Target Neighborhood Hits	438	Shared Neighborhood Hits	189
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

LEUK_HUMAN
NC score	0.038401 (rank : 1456)	θ value	0.47712 (rank : 1262)
Query Neighborhood Hits	1959	Target Neighborhood Hits	213	Shared Neighborhood Hits	87
SwissProt Accessions	P16150	Gene names	SPN, CD43
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Galactoglycoprotein) (GALGP) (CD43 antigen).

CCD45_MOUSE
NC score	0.037610 (rank : 1457)	θ value	0.365318 (rank : 1204)
Query Neighborhood Hits	1959	Target Neighborhood Hits	663	Shared Neighborhood Hits	127
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

PPRB_MOUSE
NC score	0.037554 (rank : 1458)	θ value	1.06291 (rank : 1399)
Query Neighborhood Hits	1959	Target Neighborhood Hits	354	Shared Neighborhood Hits	133
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

SYP2L_HUMAN
NC score	0.037409 (rank : 1459)	θ value	0.47712 (rank : 1268)
Query Neighborhood Hits	1959	Target Neighborhood Hits	400	Shared Neighborhood Hits	173
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

PTN23_MOUSE
NC score	0.037270 (rank : 1460)	θ value	0.125558 (rank : 1128)
Query Neighborhood Hits	1959	Target Neighborhood Hits	726	Shared Neighborhood Hits	249
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

TENS4_MOUSE
NC score	0.037212 (rank : 1461)	θ value	8.99809 (rank : 1945)
Query Neighborhood Hits	1959	Target Neighborhood Hits	225	Shared Neighborhood Hits	114
SwissProt Accessions	Q8BZ33, Q3TCM8, Q7TNR5	Gene names	Tns4
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor.

CA065_HUMAN
NC score	0.036935 (rank : 1462)	θ value	2.36792 (rank : 1523)
Query Neighborhood Hits	1959	Target Neighborhood Hits	469	Shared Neighborhood Hits	85
SwissProt Accessions	Q8N715, Q8N746, Q8NA93	Gene names	C1orf65
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf65.

SHC1_MOUSE
NC score	0.036904 (rank : 1463)	θ value	8.99809 (rank : 1937)
Query Neighborhood Hits	1959	Target Neighborhood Hits	180	Shared Neighborhood Hits	64
SwissProt Accessions	P98083, Q3U2Q7, Q8BFY3, Q8K4C6, Q8K4C7	Gene names	Shc1, Shc, ShcA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

RP3A_MOUSE
NC score	0.036898 (rank : 1464)	θ value	0.0113563 (rank : 1004)
Query Neighborhood Hits	1959	Target Neighborhood Hits	510	Shared Neighborhood Hits	203
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SVIL_MOUSE
NC score	0.036669 (rank : 1465)	θ value	0.0113563 (rank : 1005)
Query Neighborhood Hits	1959	Target Neighborhood Hits	439	Shared Neighborhood Hits	131
SwissProt Accessions	Q8K4L3	Gene names	Svil
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

SYNPO_MOUSE
NC score	0.036325 (rank : 1466)	θ value	1.81305 (rank : 1513)
Query Neighborhood Hits	1959	Target Neighborhood Hits	242	Shared Neighborhood Hits	133
SwissProt Accessions	Q8CC35, Q99JI0	Gene names	Synpo, Kiaa1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

ZN645_HUMAN
NC score	0.036284 (rank : 1467)	θ value	1.81305 (rank : 1518)
Query Neighborhood Hits	1959	Target Neighborhood Hits	265	Shared Neighborhood Hits	108
SwissProt Accessions	Q8N7E2, Q6DJY9	Gene names	ZNF645
Domain Architecture	No domain graphic available
Description	Zinc finger protein 645.

PININ_HUMAN
NC score	0.036184 (rank : 1468)	θ value	8.99809 (rank : 1927)
Query Neighborhood Hits	1959	Target Neighborhood Hits	753	Shared Neighborhood Hits	140
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

PHC2_HUMAN
NC score	0.035974 (rank : 1469)	θ value	1.06291 (rank : 1398)
Query Neighborhood Hits	1959	Target Neighborhood Hits	388	Shared Neighborhood Hits	179
SwissProt Accessions	Q8IXK0, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7	Gene names	PHC2, EDR2, PH2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2).

SYN3_HUMAN
NC score	0.035417 (rank : 1470)	θ value	0.0252991 (rank : 1031)
Query Neighborhood Hits	1959	Target Neighborhood Hits	203	Shared Neighborhood Hits	98
SwissProt Accessions	O14994	Gene names	SYN3
Domain Architecture
Description	Synapsin-3 (Synapsin III).

PHLB1_MOUSE
NC score	0.035361 (rank : 1471)	θ value	0.0563607 (rank : 1076)
Query Neighborhood Hits	1959	Target Neighborhood Hits	678	Shared Neighborhood Hits	174
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

MEGF9_MOUSE
NC score	0.035254 (rank : 1472)	θ value	5.27518 (rank : 1760)
Query Neighborhood Hits	1959	Target Neighborhood Hits	896	Shared Neighborhood Hits	292
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

WASF4_HUMAN
NC score	0.035231 (rank : 1473)	θ value	3.0926 (rank : 1628)
Query Neighborhood Hits	1959	Target Neighborhood Hits	282	Shared Neighborhood Hits	153
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

CTDP1_HUMAN
NC score	0.034859 (rank : 1474)	θ value	0.47712 (rank : 1247)
Query Neighborhood Hits	1959	Target Neighborhood Hits	416	Shared Neighborhood Hits	190
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

IRS2_HUMAN
NC score	0.034772 (rank : 1475)	θ value	0.62314 (rank : 1294)
Query Neighborhood Hits	1959	Target Neighborhood Hits	262	Shared Neighborhood Hits	131
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

BTNL1_MOUSE
NC score	0.034590 (rank : 1476)	θ value	4.03905 (rank : 1639)
Query Neighborhood Hits	1959	Target Neighborhood Hits	151	Shared Neighborhood Hits	76
SwissProt Accessions	Q7TST0, O70356	Gene names	Btnl1, Btnl3, Gm316, Ng10
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 1 precursor.

BTBDC_HUMAN
NC score	0.034585 (rank : 1477)	θ value	1.06291 (rank : 1363)
Query Neighborhood Hits	1959	Target Neighborhood Hits	248	Shared Neighborhood Hits	96
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

BRD4_HUMAN
NC score	0.034396 (rank : 1478)	θ value	8.99809 (rank : 1875)
Query Neighborhood Hits	1959	Target Neighborhood Hits	851	Shared Neighborhood Hits	282
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

DNMBP_HUMAN
NC score	0.034326 (rank : 1479)	θ value	0.279714 (rank : 1179)
Query Neighborhood Hits	1959	Target Neighborhood Hits	413	Shared Neighborhood Hits	91
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

CF150_HUMAN
NC score	0.034163 (rank : 1480)	θ value	0.62314 (rank : 1287)
Query Neighborhood Hits	1959	Target Neighborhood Hits	96	Shared Neighborhood Hits	50
SwissProt Accessions	Q8N884, Q32NC9, Q5SWL0, Q5SWL1, Q96E45	Gene names	C6orf150
Domain Architecture	No domain graphic available
Description	Protein C6orf150.

BAZ2A_MOUSE
NC score	0.034053 (rank : 1481)	θ value	1.06291 (rank : 1361)
Query Neighborhood Hits	1959	Target Neighborhood Hits	744	Shared Neighborhood Hits	267
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

MILK1_HUMAN
NC score	0.033822 (rank : 1482)	θ value	1.06291 (rank : 1390)
Query Neighborhood Hits	1959	Target Neighborhood Hits	427	Shared Neighborhood Hits	181
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

LARP4_MOUSE
NC score	0.033822 (rank : 1483)	θ value	0.0961366 (rank : 1109)
Query Neighborhood Hits	1959	Target Neighborhood Hits	260	Shared Neighborhood Hits	122
SwissProt Accessions	Q8BWW4, Q3UR69	Gene names	Larp4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

FMNL_HUMAN
NC score	0.033659 (rank : 1484)	θ value	5.27518 (rank : 1739)
Query Neighborhood Hits	1959	Target Neighborhood Hits	529	Shared Neighborhood Hits	192
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

JPH2_MOUSE
NC score	0.033653 (rank : 1485)	θ value	0.000158464 (rank : 856)
Query Neighborhood Hits	1959	Target Neighborhood Hits	279	Shared Neighborhood Hits	121
SwissProt Accessions	Q9ET78, Q9ET79	Gene names	Jph2, Jp2
Domain Architecture	No domain graphic available
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

WASF2_HUMAN
NC score	0.033556 (rank : 1486)	θ value	8.99809 (rank : 1953)
Query Neighborhood Hits	1959	Target Neighborhood Hits	280	Shared Neighborhood Hits	151
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

MNT_MOUSE
NC score	0.033383 (rank : 1487)	θ value	5.27518 (rank : 1764)
Query Neighborhood Hits	1959	Target Neighborhood Hits	432	Shared Neighborhood Hits	150
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

PTN23_HUMAN
NC score	0.033305 (rank : 1488)	θ value	0.279714 (rank : 1193)
Query Neighborhood Hits	1959	Target Neighborhood Hits	646	Shared Neighborhood Hits	206
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

PDC6I_HUMAN
NC score	0.033289 (rank : 1489)	θ value	1.38821 (rank : 1452)
Query Neighborhood Hits	1959	Target Neighborhood Hits	278	Shared Neighborhood Hits	124
SwissProt Accessions	Q8WUM4, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5	Gene names	PDCD6IP, AIP1, ALIX, KIAA1375
Domain Architecture
Description	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95).

CRSP2_HUMAN
NC score	0.033272 (rank : 1490)	θ value	6.88961 (rank : 1805)
Query Neighborhood Hits	1959	Target Neighborhood Hits	380	Shared Neighborhood Hits	167
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

BAT3_MOUSE
NC score	0.033114 (rank : 1491)	θ value	8.99809 (rank : 1869)
Query Neighborhood Hits	1959	Target Neighborhood Hits	518	Shared Neighborhood Hits	212
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

RFX1_HUMAN
NC score	0.032868 (rank : 1492)	θ value	0.365318 (rank : 1233)
Query Neighborhood Hits	1959	Target Neighborhood Hits	256	Shared Neighborhood Hits	137
SwissProt Accessions	P22670	Gene names	RFX1
Domain Architecture
Description	MHC class II regulatory factor RFX1 (RFX) (Enhancer factor C) (EF-C).

RP3A_HUMAN
NC score	0.032749 (rank : 1493)	θ value	0.00509761 (rank : 976)
Query Neighborhood Hits	1959	Target Neighborhood Hits	305	Shared Neighborhood Hits	93
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

CRTC1_MOUSE
NC score	0.032742 (rank : 1494)	θ value	0.813845 (rank : 1321)
Query Neighborhood Hits	1959	Target Neighborhood Hits	230	Shared Neighborhood Hits	117
SwissProt Accessions	Q68ED7, Q6ZQ85	Gene names	Crtc1, Kiaa0616, Mect1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1 homolog).

MYO9B_HUMAN
NC score	0.032462 (rank : 1495)	θ value	8.99809 (rank : 1921)
Query Neighborhood Hits	1959	Target Neighborhood Hits	641	Shared Neighborhood Hits	234
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

ZN385_HUMAN
NC score	0.032417 (rank : 1496)	θ value	6.88961 (rank : 1862)
Query Neighborhood Hits	1959	Target Neighborhood Hits	614	Shared Neighborhood Hits	230
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

BAT3_HUMAN
NC score	0.032237 (rank : 1497)	θ value	5.27518 (rank : 1720)
Query Neighborhood Hits	1959	Target Neighborhood Hits	490	Shared Neighborhood Hits	193
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

ACD_HUMAN
NC score	0.032023 (rank : 1498)	θ value	4.03905 (rank : 1632)
Query Neighborhood Hits	1959	Target Neighborhood Hits	143	Shared Neighborhood Hits	80
SwissProt Accessions	Q96AP0, Q562H5, Q9H8F9	Gene names	ACD, PIP1, PTOP
Domain Architecture	No domain graphic available
Description	Adrenocortical dysplasia protein homolog (POT1 and TIN2-interacting protein).

SDC3_MOUSE
NC score	0.032021 (rank : 1499)	θ value	5.27518 (rank : 1781)
Query Neighborhood Hits	1959	Target Neighborhood Hits	107	Shared Neighborhood Hits	60
SwissProt Accessions	Q64519, Q3UDD9, Q6ZQA4, Q7TQD4	Gene names	Sdc3, Kiaa0468
Domain Architecture
Description	Syndecan-3 precursor (SYND3).

TXND2_MOUSE
NC score	0.031819 (rank : 1500)	θ value	0.365318 (rank : 1241)
Query Neighborhood Hits	1959	Target Neighborhood Hits	828	Shared Neighborhood Hits	166
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

SGIP1_HUMAN
NC score	0.031731 (rank : 1501)	θ value	1.06291 (rank : 1409)
Query Neighborhood Hits	1959	Target Neighborhood Hits	198	Shared Neighborhood Hits	98
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

IF4G1_MOUSE
NC score	0.031255 (rank : 1502)	θ value	4.03905 (rank : 1664)
Query Neighborhood Hits	1959	Target Neighborhood Hits	534	Shared Neighborhood Hits	214
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

3BP2_HUMAN
NC score	0.031247 (rank : 1503)	θ value	3.0926 (rank : 1573)
Query Neighborhood Hits	1959	Target Neighborhood Hits	296	Shared Neighborhood Hits	131
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

BAZ2A_HUMAN
NC score	0.031107 (rank : 1504)	θ value	1.06291 (rank : 1360)
Query Neighborhood Hits	1959	Target Neighborhood Hits	780	Shared Neighborhood Hits	260
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

K2027_HUMAN
NC score	0.030813 (rank : 1505)	θ value	2.36792 (rank : 1541)
Query Neighborhood Hits	1959	Target Neighborhood Hits	194	Shared Neighborhood Hits	84
SwissProt Accessions	Q6ZVF9, Q8IVE4	Gene names	KIAA2027
Domain Architecture	No domain graphic available
Description	Protein KIAA2027.

RBBP6_HUMAN
NC score	0.030748 (rank : 1506)	θ value	0.813845 (rank : 1345)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1135	Shared Neighborhood Hits	239
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

AFF1_MOUSE
NC score	0.030728 (rank : 1507)	θ value	8.99809 (rank : 1864)
Query Neighborhood Hits	1959	Target Neighborhood Hits	351	Shared Neighborhood Hits	131
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

SYN2_HUMAN
NC score	0.030338 (rank : 1508)	θ value	2.36792 (rank : 1567)
Query Neighborhood Hits	1959	Target Neighborhood Hits	213	Shared Neighborhood Hits	113
SwissProt Accessions	Q92777	Gene names	SYN2
Domain Architecture
Description	Synapsin-2 (Synapsin II).

FMN1A_MOUSE
NC score	0.030229 (rank : 1509)	θ value	6.88961 (rank : 1821)
Query Neighborhood Hits	1959	Target Neighborhood Hits	423	Shared Neighborhood Hits	170
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

SVIL_HUMAN
NC score	0.030142 (rank : 1510)	θ value	0.0330416 (rank : 1048)
Query Neighborhood Hits	1959	Target Neighborhood Hits	232	Shared Neighborhood Hits	78
SwissProt Accessions	O95425, O60611, O60612, Q5VZK5, Q5VZK6, Q9H1R7	Gene names	SVIL
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

DNMBP_MOUSE
NC score	0.029668 (rank : 1511)	θ value	5.27518 (rank : 1731)
Query Neighborhood Hits	1959	Target Neighborhood Hits	435	Shared Neighborhood Hits	116
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

RIMS1_HUMAN
NC score	0.029657 (rank : 1512)	θ value	1.81305 (rank : 1511)
Query Neighborhood Hits	1959	Target Neighborhood Hits	437	Shared Neighborhood Hits	113
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

ZN318_HUMAN
NC score	0.029482 (rank : 1513)	θ value	0.813845 (rank : 1354)
Query Neighborhood Hits	1959	Target Neighborhood Hits	497	Shared Neighborhood Hits	115
SwissProt Accessions	Q5VUA4, O94796, Q4G0E4, Q8NEM6, Q9UNU8, Q9Y2W9	Gene names	ZNF318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Endocrine regulatory protein).

TXLNA_HUMAN
NC score	0.029430 (rank : 1514)	θ value	0.813845 (rank : 1353)
Query Neighborhood Hits	1959	Target Neighborhood Hits	982	Shared Neighborhood Hits	175
SwissProt Accessions	P40222, Q66K62, Q86T54, Q86T85, Q86T86, Q86Y86, Q86YW3, Q8N2Y3	Gene names	TXLNA, TXLN
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

SSBP4_HUMAN
NC score	0.029424 (rank : 1515)	θ value	5.27518 (rank : 1785)
Query Neighborhood Hits	1959	Target Neighborhood Hits	753	Shared Neighborhood Hits	267
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

FMN1B_MOUSE
NC score	0.029364 (rank : 1516)	θ value	6.88961 (rank : 1822)
Query Neighborhood Hits	1959	Target Neighborhood Hits	447	Shared Neighborhood Hits	168
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

SYP2L_MOUSE
NC score	0.029200 (rank : 1517)	θ value	3.0926 (rank : 1623)
Query Neighborhood Hits	1959	Target Neighborhood Hits	289	Shared Neighborhood Hits	114
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

ATX7_HUMAN
NC score	0.028980 (rank : 1518)	θ value	4.03905 (rank : 1635)
Query Neighborhood Hits	1959	Target Neighborhood Hits	351	Shared Neighborhood Hits	163
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

COTE1_HUMAN
NC score	0.028963 (rank : 1519)	θ value	0.00390308 (rank : 960)
Query Neighborhood Hits	1959	Target Neighborhood Hits	40	Shared Neighborhood Hits	12
SwissProt Accessions	P81408	Gene names	C1orf2, COTE1
Domain Architecture	No domain graphic available
Description	Protein COTE1.

MYO15_HUMAN
NC score	0.028776 (rank : 1520)	θ value	0.0330416 (rank : 1039)
Query Neighborhood Hits	1959	Target Neighborhood Hits	671	Shared Neighborhood Hits	286
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

BPTF_HUMAN
NC score	0.028716 (rank : 1521)	θ value	0.47712 (rank : 1244)
Query Neighborhood Hits	1959	Target Neighborhood Hits	786	Shared Neighborhood Hits	201
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

IF4G1_HUMAN
NC score	0.028538 (rank : 1522)	θ value	6.88961 (rank : 1827)
Query Neighborhood Hits	1959	Target Neighborhood Hits	347	Shared Neighborhood Hits	139
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

ALO17_HUMAN
NC score	0.028409 (rank : 1523)	θ value	0.125558 (rank : 1115)
Query Neighborhood Hits	1959	Target Neighborhood Hits	317	Shared Neighborhood Hits	79
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

ELOA3_HUMAN
NC score	0.028272 (rank : 1524)	θ value	0.00665767 (rank : 980)
Query Neighborhood Hits	1959	Target Neighborhood Hits	98	Shared Neighborhood Hits	44
SwissProt Accessions	Q8NG57	Gene names	TCEB3C, TCEB3L2
Domain Architecture
Description	RNA polymerase II transcription factor SIII subunit A3 (Elongin-A3) (EloA3) (Transcription elongation factor B polypeptide 3C).

ALMS1_HUMAN
NC score	0.028132 (rank : 1525)	θ value	5.27518 (rank : 1711)
Query Neighborhood Hits	1959	Target Neighborhood Hits	356	Shared Neighborhood Hits	127
SwissProt Accessions	Q8TCU4, Q53S05, Q580Q8, Q86VP9, Q9Y4G4	Gene names	ALMS1, KIAA0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1.

WBS14_MOUSE
NC score	0.028067 (rank : 1526)	θ value	1.38821 (rank : 1463)
Query Neighborhood Hits	1959	Target Neighborhood Hits	171	Shared Neighborhood Hits	75
SwissProt Accessions	Q99MZ3, Q99MY9, Q99MZ0, Q99MZ1, Q99MZ2, Q9JLM5	Gene names	Mlxipl, Mio, Wbscr14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein homolog (Mlx interactor) (MLX-interacting protein-like).

SFR11_HUMAN
NC score	0.027958 (rank : 1527)	θ value	2.36792 (rank : 1564)
Query Neighborhood Hits	1959	Target Neighborhood Hits	246	Shared Neighborhood Hits	62
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

XRCC1_HUMAN
NC score	0.027897 (rank : 1528)	θ value	0.47712 (rank : 1280)
Query Neighborhood Hits	1959	Target Neighborhood Hits	131	Shared Neighborhood Hits	51
SwissProt Accessions	P18887, Q9HCB1	Gene names	XRCC1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

PHC1_HUMAN
NC score	0.027865 (rank : 1529)	θ value	0.0961366 (rank : 1110)
Query Neighborhood Hits	1959	Target Neighborhood Hits	227	Shared Neighborhood Hits	91
SwissProt Accessions	P78364, Q8WVM3, Q9BU63	Gene names	PHC1, EDR1, PH1
Domain Architecture
Description	Polyhomeotic-like protein 1 (hPH1) (Early development regulatory protein 1).

K0460_MOUSE
NC score	0.027510 (rank : 1530)	θ value	1.06291 (rank : 1386)
Query Neighborhood Hits	1959	Target Neighborhood Hits	374	Shared Neighborhood Hits	114
SwissProt Accessions	Q6NXI6, Q3U3L8, Q6ZQA7	Gene names	Kiaa0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

PKHA6_MOUSE
NC score	0.027483 (rank : 1531)	θ value	4.03905 (rank : 1679)
Query Neighborhood Hits	1959	Target Neighborhood Hits	591	Shared Neighborhood Hits	167
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

JIP2_HUMAN
NC score	0.027210 (rank : 1532)	θ value	3.0926 (rank : 1596)
Query Neighborhood Hits	1959	Target Neighborhood Hits	288	Shared Neighborhood Hits	106
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

MILK2_HUMAN
NC score	0.027014 (rank : 1533)	θ value	0.365318 (rank : 1224)
Query Neighborhood Hits	1959	Target Neighborhood Hits	457	Shared Neighborhood Hits	156
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

HCLS1_HUMAN
NC score	0.026921 (rank : 1534)	θ value	5.27518 (rank : 1743)
Query Neighborhood Hits	1959	Target Neighborhood Hits	358	Shared Neighborhood Hits	132
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

CUTL1_MOUSE
NC score	0.026573 (rank : 1535)	θ value	0.00035302 (rank : 877)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1620	Shared Neighborhood Hits	279
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

SFR17_HUMAN
NC score	0.026522 (rank : 1536)	θ value	6.88961 (rank : 1846)
Query Neighborhood Hits	1959	Target Neighborhood Hits	325	Shared Neighborhood Hits	66
SwissProt Accessions	Q8TF01, Q5T064, Q6P2B4, Q6P2N4, Q6PJ93, Q6PK36, Q7Z640, Q8TF00, Q96K10, Q96SM5, Q9P076, Q9P0C0, Q9Y4N3	Gene names	SRRP130, C6orf111
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 130 (Serine-arginine-rich- splicing regulatory protein 130) (SRrp130) (SR-rich protein) (SR- related protein).

NPAS4_MOUSE
NC score	0.026518 (rank : 1537)	θ value	0.62314 (rank : 1301)
Query Neighborhood Hits	1959	Target Neighborhood Hits	245	Shared Neighborhood Hits	107
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

CE025_HUMAN
NC score	0.026443 (rank : 1538)	θ value	0.813845 (rank : 1316)
Query Neighborhood Hits	1959	Target Neighborhood Hits	114	Shared Neighborhood Hits	53
SwissProt Accessions	Q8NDZ2, Q6NXN8, Q6ZTU4, Q8IZ15	Gene names	C5orf25
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C5orf25.

SWP70_MOUSE
NC score	0.026378 (rank : 1539)	θ value	6.88961 (rank : 1848)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1097	Shared Neighborhood Hits	137
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

REXO1_HUMAN
NC score	0.026335 (rank : 1540)	θ value	0.62314 (rank : 1305)
Query Neighborhood Hits	1959	Target Neighborhood Hits	242	Shared Neighborhood Hits	104
SwissProt Accessions	Q8N1G1, Q9ULT2	Gene names	REXO1, ELOABP1, KIAA1138, TCEB3BP1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Elongin A-binding protein 1) (EloA-BP1) (Transcription elongation factor B polypeptide 3-binding protein 1).

TPO_MOUSE
NC score	0.026322 (rank : 1541)	θ value	3.0926 (rank : 1625)
Query Neighborhood Hits	1959	Target Neighborhood Hits	258	Shared Neighborhood Hits	110
SwissProt Accessions	P40226	Gene names	Thpo
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

RTN1_MOUSE
NC score	0.026247 (rank : 1542)	θ value	0.125558 (rank : 1129)
Query Neighborhood Hits	1959	Target Neighborhood Hits	189	Shared Neighborhood Hits	95
SwissProt Accessions	Q8K0T0, Q8K4S4	Gene names	Rtn1, Nsp
Domain Architecture	No domain graphic available
Description	Reticulon-1 (Neuroendocrine-specific protein).

CJ108_HUMAN
NC score	0.026153 (rank : 1543)	θ value	8.99809 (rank : 1884)
Query Neighborhood Hits	1959	Target Neighborhood Hits	165	Shared Neighborhood Hits	80
SwissProt Accessions	Q8N8Z3	Gene names	C10orf108
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C10orf108.

NFH_HUMAN
NC score	0.026046 (rank : 1544)	θ value	0.0330416 (rank : 1041)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1242	Shared Neighborhood Hits	269
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PER3_HUMAN
NC score	0.026036 (rank : 1545)	θ value	2.36792 (rank : 1553)
Query Neighborhood Hits	1959	Target Neighborhood Hits	479	Shared Neighborhood Hits	192
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

GTSE1_MOUSE
NC score	0.026027 (rank : 1546)	θ value	6.88961 (rank : 1824)
Query Neighborhood Hits	1959	Target Neighborhood Hits	245	Shared Neighborhood Hits	119
SwissProt Accessions	Q8R080, O89015, Q9CSG9	Gene names	Gtse1, B99
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (Gtse-1) (B99 protein).

AIM1_HUMAN
NC score	0.025935 (rank : 1547)	θ value	0.125558 (rank : 1112)
Query Neighborhood Hits	1959	Target Neighborhood Hits	247	Shared Neighborhood Hits	100
SwissProt Accessions	Q9Y4K1, O00296, Q5VWJ2	Gene names	AIM1
Domain Architecture
Description	Absent in melanoma 1 protein.

HCN2_HUMAN
NC score	0.025879 (rank : 1548)	θ value	0.21417 (rank : 1155)
Query Neighborhood Hits	1959	Target Neighborhood Hits	369	Shared Neighborhood Hits	156
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

IF35_MOUSE
NC score	0.025832 (rank : 1549)	θ value	8.99809 (rank : 1908)
Query Neighborhood Hits	1959	Target Neighborhood Hits	210	Shared Neighborhood Hits	109
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

SNIP_MOUSE
NC score	0.025817 (rank : 1550)	θ value	0.365318 (rank : 1237)
Query Neighborhood Hits	1959	Target Neighborhood Hits	319	Shared Neighborhood Hits	96
SwissProt Accessions	Q9QWI6, O70298	Gene names	P140, Kiaa1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

MYCB2_HUMAN
NC score	0.025788 (rank : 1551)	θ value	1.38821 (rank : 1448)
Query Neighborhood Hits	1959	Target Neighborhood Hits	390	Shared Neighborhood Hits	104
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

GA2L1_MOUSE
NC score	0.025735 (rank : 1552)	θ value	0.365318 (rank : 1212)
Query Neighborhood Hits	1959	Target Neighborhood Hits	114	Shared Neighborhood Hits	54
SwissProt Accessions	Q8JZP9, Q5SVG0, Q8K573	Gene names	Gas2l1
Domain Architecture	No domain graphic available
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1).

PDC6I_MOUSE
NC score	0.025647 (rank : 1553)	θ value	1.06291 (rank : 1397)
Query Neighborhood Hits	1959	Target Neighborhood Hits	275	Shared Neighborhood Hits	105
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

CNTRB_HUMAN
NC score	0.025644 (rank : 1554)	θ value	1.38821 (rank : 1427)
Query Neighborhood Hits	1959	Target Neighborhood Hits	690	Shared Neighborhood Hits	97
SwissProt Accessions	Q8N137, Q331K3, Q69YV7, Q8NCB8, Q8WXV3, Q96CQ7, Q9C060	Gene names	CNTROB, LIP8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

JIP1_HUMAN
NC score	0.025637 (rank : 1555)	θ value	3.0926 (rank : 1595)
Query Neighborhood Hits	1959	Target Neighborhood Hits	271	Shared Neighborhood Hits	120
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

PHLPP_HUMAN
NC score	0.025536 (rank : 1556)	θ value	2.36792 (rank : 1554)
Query Neighborhood Hits	1959	Target Neighborhood Hits	604	Shared Neighborhood Hits	178
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

CJ047_HUMAN
NC score	0.025503 (rank : 1557)	θ value	0.47712 (rank : 1245)
Query Neighborhood Hits	1959	Target Neighborhood Hits	164	Shared Neighborhood Hits	80
SwissProt Accessions	Q86WR7, Q5W0J9, Q5W0K0, Q5W0K1, Q5W0K2, Q6PJC8, Q8N317	Gene names	C10orf47
Domain Architecture	No domain graphic available
Description	Protein C10orf47.

EVL_HUMAN
NC score	0.025427 (rank : 1558)	θ value	5.27518 (rank : 1738)
Query Neighborhood Hits	1959	Target Neighborhood Hits	260	Shared Neighborhood Hits	129
SwissProt Accessions	Q9UI08, O95884, Q7Z522, Q8TBV1, Q9UF25, Q9UIC2	Gene names	EVL, RNB6
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

ELOA2_HUMAN
NC score	0.025394 (rank : 1559)	θ value	0.21417 (rank : 1153)
Query Neighborhood Hits	1959	Target Neighborhood Hits	165	Shared Neighborhood Hits	59
SwissProt Accessions	Q8IYF1, Q9P2V9	Gene names	TCEB3B, TCEB3L
Domain Architecture
Description	RNA polymerase II transcription factor SIII subunit A2 (Elongin-A2) (EloA2) (Transcription elongation factor B polypeptide 3B).

ARMX2_HUMAN
NC score	0.025370 (rank : 1560)	θ value	0.365318 (rank : 1202)
Query Neighborhood Hits	1959	Target Neighborhood Hits	134	Shared Neighborhood Hits	57
SwissProt Accessions	Q7L311, O60267, Q5H9D9	Gene names	ARMCX2, ALEX2, KIAA0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2 (Protein ALEX2) (ARM protein lost in epithelial cancers on chromosome X 2).

CT032_HUMAN
NC score	0.025287 (rank : 1561)	θ value	0.365318 (rank : 1205)
Query Neighborhood Hits	1959	Target Neighborhood Hits	235	Shared Neighborhood Hits	77
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

GAB1_HUMAN
NC score	0.025276 (rank : 1562)	θ value	0.62314 (rank : 1291)
Query Neighborhood Hits	1959	Target Neighborhood Hits	279	Shared Neighborhood Hits	124
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

NEB2_MOUSE
NC score	0.025213 (rank : 1563)	θ value	0.0193708 (rank : 1019)
Query Neighborhood Hits	1959	Target Neighborhood Hits	889	Shared Neighborhood Hits	142
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

ANR11_HUMAN
NC score	0.025026 (rank : 1564)	θ value	5.27518 (rank : 1714)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1289	Shared Neighborhood Hits	294
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

CECR2_HUMAN
NC score	0.024960 (rank : 1565)	θ value	5.27518 (rank : 1724)
Query Neighborhood Hits	1959	Target Neighborhood Hits	543	Shared Neighborhood Hits	192
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

ASXL1_HUMAN
NC score	0.024728 (rank : 1566)	θ value	0.21417 (rank : 1149)
Query Neighborhood Hits	1959	Target Neighborhood Hits	260	Shared Neighborhood Hits	84
SwissProt Accessions	Q8IXJ9, Q5JWS9, Q8IYY7, Q9H466, Q9NQF8, Q9UFJ0, Q9UFP8, Q9Y2I4	Gene names	ASXL1, KIAA0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

IF39_MOUSE
NC score	0.024496 (rank : 1567)	θ value	1.38821 (rank : 1440)
Query Neighborhood Hits	1959	Target Neighborhood Hits	206	Shared Neighborhood Hits	74
SwissProt Accessions	Q8JZQ9, Q922K2	Gene names	Eif3s9
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116).

MORC2_HUMAN
NC score	0.024459 (rank : 1568)	θ value	0.0736092 (rank : 1092)
Query Neighborhood Hits	1959	Target Neighborhood Hits	207	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y6X9, Q9UF28, Q9Y6V2	Gene names	MORC2, KIAA0852, ZCWCC1
Domain Architecture
Description	MORC family CW-type zinc finger protein 2 (Zinc finger CW-type coiled- coil domain protein 1).

FYB_MOUSE
NC score	0.024456 (rank : 1569)	θ value	0.47712 (rank : 1251)
Query Neighborhood Hits	1959	Target Neighborhood Hits	194	Shared Neighborhood Hits	64
SwissProt Accessions	O35601, Q9Z2H3	Gene names	Fyb
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

CN092_MOUSE
NC score	0.024429 (rank : 1570)	θ value	0.0113563 (rank : 1000)
Query Neighborhood Hits	1959	Target Neighborhood Hits	206	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BU11, Q80UI2, Q99PN9, Q9CS16	Gene names
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

BAG4_HUMAN
NC score	0.024309 (rank : 1571)	θ value	0.0961366 (rank : 1101)
Query Neighborhood Hits	1959	Target Neighborhood Hits	96	Shared Neighborhood Hits	38
SwissProt Accessions	O95429, O95818	Gene names	BAG4, SODD
Domain Architecture
Description	BAG family molecular chaperone regulator 4 (BCL2-associated athanogene 4) (BAG-4) (Silencer of death domains).

APC_MOUSE
NC score	0.024149 (rank : 1572)	θ value	0.279714 (rank : 1175)
Query Neighborhood Hits	1959	Target Neighborhood Hits	441	Shared Neighborhood Hits	114
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

CCDC6_HUMAN
NC score	0.023949 (rank : 1573)	θ value	0.125558 (rank : 1117)
Query Neighborhood Hits	1959	Target Neighborhood Hits	723	Shared Neighborhood Hits	116
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

IF3A_MOUSE
NC score	0.023885 (rank : 1574)	θ value	6.88961 (rank : 1826)
Query Neighborhood Hits	1959	Target Neighborhood Hits	871	Shared Neighborhood Hits	115
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

ARMX2_MOUSE
NC score	0.023840 (rank : 1575)	θ value	1.81305 (rank : 1467)
Query Neighborhood Hits	1959	Target Neighborhood Hits	349	Shared Neighborhood Hits	158
SwissProt Accessions	Q6A058, Q9CXI9	Gene names	Armcx2, Kiaa0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2.

MYCB2_MOUSE
NC score	0.023786 (rank : 1576)	θ value	0.163984 (rank : 1137)
Query Neighborhood Hits	1959	Target Neighborhood Hits	307	Shared Neighborhood Hits	74
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

MUC_MOUSE
NC score	0.023732 (rank : 1577)	θ value	0.279714 (rank : 1189)
Query Neighborhood Hits	1959	Target Neighborhood Hits	242	Shared Neighborhood Hits	44
SwissProt Accessions	P01872	Gene names
Domain Architecture	No domain graphic available
Description	Ig mu chain C region secreted form.

GPTC8_HUMAN
NC score	0.023699 (rank : 1578)	θ value	5.27518 (rank : 1740)
Query Neighborhood Hits	1959	Target Neighborhood Hits	366	Shared Neighborhood Hits	105
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

3BP2_MOUSE
NC score	0.023639 (rank : 1579)	θ value	5.27518 (rank : 1708)
Query Neighborhood Hits	1959	Target Neighborhood Hits	142	Shared Neighborhood Hits	57
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

IF3A_HUMAN
NC score	0.023624 (rank : 1580)	θ value	4.03905 (rank : 1663)
Query Neighborhood Hits	1959	Target Neighborhood Hits	875	Shared Neighborhood Hits	112
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

CUTL2_HUMAN
NC score	0.023614 (rank : 1581)	θ value	0.125558 (rank : 1119)
Query Neighborhood Hits	1959	Target Neighborhood Hits	906	Shared Neighborhood Hits	188
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

AFAD_HUMAN
NC score	0.023609 (rank : 1582)	θ value	3.0926 (rank : 1574)
Query Neighborhood Hits	1959	Target Neighborhood Hits	689	Shared Neighborhood Hits	136
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

ZN318_MOUSE
NC score	0.023603 (rank : 1583)	θ value	1.06291 (rank : 1419)
Query Neighborhood Hits	1959	Target Neighborhood Hits	642	Shared Neighborhood Hits	135
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

LARP4_HUMAN
NC score	0.023527 (rank : 1584)	θ value	0.0736092 (rank : 1090)
Query Neighborhood Hits	1959	Target Neighborhood Hits	69	Shared Neighborhood Hits	28
SwissProt Accessions	Q71RC2, Q5CZ97, Q96NF9	Gene names	LARP4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

FA61A_MOUSE
NC score	0.023505 (rank : 1585)	θ value	1.38821 (rank : 1431)
Query Neighborhood Hits	1959	Target Neighborhood Hits	81	Shared Neighborhood Hits	46
SwissProt Accessions	Q8K2F8, Q9CTG8	Gene names	Fam61a
Domain Architecture	No domain graphic available
Description	Protein FAM61A.

PRGC2_HUMAN
NC score	0.023466 (rank : 1586)	θ value	2.36792 (rank : 1557)
Query Neighborhood Hits	1959	Target Neighborhood Hits	272	Shared Neighborhood Hits	105
SwissProt Accessions	Q86YN6, Q86YN3, Q86YN4, Q86YN5, Q8N1N9, Q8TDE4, Q8TDE5	Gene names	PPARGC1B, PERC, PGC1, PGC1B, PPARGC1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta) (PGC-1-related estrogen receptor alpha coactivator) (PPARGC-1-beta) (PGC-1-beta).

NPAS4_HUMAN
NC score	0.023277 (rank : 1587)	θ value	0.365318 (rank : 1228)
Query Neighborhood Hits	1959	Target Neighborhood Hits	214	Shared Neighborhood Hits	88
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

IF4B_MOUSE
NC score	0.023266 (rank : 1588)	θ value	0.21417 (rank : 1156)
Query Neighborhood Hits	1959	Target Neighborhood Hits	368	Shared Neighborhood Hits	131
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

MUCM_MOUSE
NC score	0.023265 (rank : 1589)	θ value	0.279714 (rank : 1188)
Query Neighborhood Hits	1959	Target Neighborhood Hits	242	Shared Neighborhood Hits	43
SwissProt Accessions	P01873	Gene names
Domain Architecture	No domain graphic available
Description	Ig mu chain C region membrane-bound form.

TULP4_MOUSE
NC score	0.023250 (rank : 1590)	θ value	0.47712 (rank : 1277)
Query Neighborhood Hits	1959	Target Neighborhood Hits	247	Shared Neighborhood Hits	68
SwissProt Accessions	Q9JIL5, Q8CA75, Q922C2	Gene names	Tulp4, Tusp
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

MPP2_MOUSE
NC score	0.023199 (rank : 1591)	θ value	4.03905 (rank : 1670)
Query Neighborhood Hits	1959	Target Neighborhood Hits	189	Shared Neighborhood Hits	36
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

PKHA6_HUMAN
NC score	0.023192 (rank : 1592)	θ value	2.36792 (rank : 1555)
Query Neighborhood Hits	1959	Target Neighborhood Hits	556	Shared Neighborhood Hits	160
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

NEB2_HUMAN
NC score	0.023176 (rank : 1593)	θ value	0.0113563 (rank : 1003)
Query Neighborhood Hits	1959	Target Neighborhood Hits	883	Shared Neighborhood Hits	139
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

WASF3_MOUSE
NC score	0.023174 (rank : 1594)	θ value	6.88961 (rank : 1859)
Query Neighborhood Hits	1959	Target Neighborhood Hits	188	Shared Neighborhood Hits	100
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

TCP10_HUMAN
NC score	0.023153 (rank : 1595)	θ value	6.88961 (rank : 1850)
Query Neighborhood Hits	1959	Target Neighborhood Hits	134	Shared Neighborhood Hits	56
SwissProt Accessions	Q12799	Gene names	TCP10, TCP10A
Domain Architecture
Description	T-complex protein 10A homolog.

3BP1_HUMAN
NC score	0.023012 (rank : 1596)	θ value	0.47712 (rank : 1243)
Query Neighborhood Hits	1959	Target Neighborhood Hits	376	Shared Neighborhood Hits	172
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

HCN4_MOUSE
NC score	0.022953 (rank : 1597)	θ value	2.36792 (rank : 1536)
Query Neighborhood Hits	1959	Target Neighborhood Hits	284	Shared Neighborhood Hits	134
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

MEGF9_HUMAN
NC score	0.022947 (rank : 1598)	θ value	1.38821 (rank : 1445)
Query Neighborhood Hits	1959	Target Neighborhood Hits	557	Shared Neighborhood Hits	150
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

DSPP_MOUSE
NC score	0.022856 (rank : 1599)	θ value	1.06291 (rank : 1370)
Query Neighborhood Hits	1959	Target Neighborhood Hits	491	Shared Neighborhood Hits	101
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

SREC2_HUMAN
NC score	0.022855 (rank : 1600)	θ value	0.00390308 (rank : 966)
Query Neighborhood Hits	1959	Target Neighborhood Hits	645	Shared Neighborhood Hits	149
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

PRRT1_MOUSE
NC score	0.022806 (rank : 1601)	θ value	3.0926 (rank : 1609)
Query Neighborhood Hits	1959	Target Neighborhood Hits	102	Shared Neighborhood Hits	48
SwissProt Accessions	O35449	Gene names	Prrt1, Ng5
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 1.

T22D4_MOUSE
NC score	0.022774 (rank : 1602)	θ value	0.47712 (rank : 1269)
Query Neighborhood Hits	1959	Target Neighborhood Hits	92	Shared Neighborhood Hits	50
SwissProt Accessions	Q9EQN3	Gene names	Tsc22d4, Tilz2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2).

MYO15_MOUSE
NC score	0.022635 (rank : 1603)	θ value	1.06291 (rank : 1393)
Query Neighborhood Hits	1959	Target Neighborhood Hits	467	Shared Neighborhood Hits	188
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

PKHA4_HUMAN
NC score	0.022493 (rank : 1604)	θ value	3.0926 (rank : 1608)
Query Neighborhood Hits	1959	Target Neighborhood Hits	283	Shared Neighborhood Hits	109
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

TACC3_HUMAN
NC score	0.022415 (rank : 1605)	θ value	6.88961 (rank : 1849)
Query Neighborhood Hits	1959	Target Neighborhood Hits	779	Shared Neighborhood Hits	180
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

AKAP2_HUMAN
NC score	0.022405 (rank : 1606)	θ value	0.125558 (rank : 1113)
Query Neighborhood Hits	1959	Target Neighborhood Hits	507	Shared Neighborhood Hits	111
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

AFF2_MOUSE
NC score	0.022367 (rank : 1607)	θ value	3.0926 (rank : 1575)
Query Neighborhood Hits	1959	Target Neighborhood Hits	225	Shared Neighborhood Hits	100
SwissProt Accessions	O55112	Gene names	Aff2, Fmr2, Ox19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation protein 2 homolog) (Protein FMR-2) (FMR2P) (Protein Ox19).

CBL_MOUSE
NC score	0.022106 (rank : 1608)	θ value	0.00869519 (rank : 992)
Query Neighborhood Hits	1959	Target Neighborhood Hits	426	Shared Neighborhood Hits	130
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

MKL1_HUMAN
NC score	0.022089 (rank : 1609)	θ value	1.06291 (rank : 1391)
Query Neighborhood Hits	1959	Target Neighborhood Hits	232	Shared Neighborhood Hits	90
SwissProt Accessions	Q969V6, Q8TCL1, Q96SC5, Q96SC6, Q9P2B0	Gene names	MKL1, KIAA1438, MAL
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein) (Megakaryocytic acute leukemia protein).

GAK6_HUMAN
NC score	0.021967 (rank : 1610)	θ value	0.813845 (rank : 1329)
Query Neighborhood Hits	1959	Target Neighborhood Hits	392	Shared Neighborhood Hits	183
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

K1210_HUMAN
NC score	0.021953 (rank : 1611)	θ value	1.38821 (rank : 1441)
Query Neighborhood Hits	1959	Target Neighborhood Hits	219	Shared Neighborhood Hits	79
SwissProt Accessions	Q9ULL0, Q5JPN4	Gene names	KIAA1210
Domain Architecture	No domain graphic available
Description	Protein KIAA1210.

GAK5_HUMAN
NC score	0.021761 (rank : 1612)	θ value	1.81305 (rank : 1486)
Query Neighborhood Hits	1959	Target Neighborhood Hits	429	Shared Neighborhood Hits	191
SwissProt Accessions	P62684	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K113 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK4_HUMAN
NC score	0.021745 (rank : 1613)	θ value	0.47712 (rank : 1254)
Query Neighborhood Hits	1959	Target Neighborhood Hits	415	Shared Neighborhood Hits	191
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAB1_MOUSE
NC score	0.021709 (rank : 1614)	θ value	0.47712 (rank : 1253)
Query Neighborhood Hits	1959	Target Neighborhood Hits	233	Shared Neighborhood Hits	92
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

GAK11_HUMAN
NC score	0.021655 (rank : 1615)	θ value	1.06291 (rank : 1376)
Query Neighborhood Hits	1959	Target Neighborhood Hits	409	Shared Neighborhood Hits	191
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

SF3A1_HUMAN
NC score	0.021559 (rank : 1616)	θ value	8.99809 (rank : 1936)
Query Neighborhood Hits	1959	Target Neighborhood Hits	199	Shared Neighborhood Hits	102
SwissProt Accessions	Q15459	Gene names	SF3A1, SAP114
Domain Architecture
Description	Splicing factor 3 subunit 1 (Spliceosome-associated protein 114) (SAP 114) (SF3a120).

K1949_MOUSE
NC score	0.021516 (rank : 1617)	θ value	5.27518 (rank : 1752)
Query Neighborhood Hits	1959	Target Neighborhood Hits	134	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BQ30, Q3UDS6, Q8CEY9, Q8R3D8	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA1949 homolog.

INVS_MOUSE
NC score	0.021487 (rank : 1618)	θ value	0.47712 (rank : 1258)
Query Neighborhood Hits	1959	Target Neighborhood Hits	609	Shared Neighborhood Hits	178
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

CCD96_HUMAN
NC score	0.021456 (rank : 1619)	θ value	3.0926 (rank : 1580)
Query Neighborhood Hits	1959	Target Neighborhood Hits	595	Shared Neighborhood Hits	123
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

DNMT1_HUMAN
NC score	0.021442 (rank : 1620)	θ value	8.99809 (rank : 1893)
Query Neighborhood Hits	1959	Target Neighborhood Hits	401	Shared Neighborhood Hits	109
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

RNF25_HUMAN
NC score	0.021429 (rank : 1621)	θ value	0.365318 (rank : 1234)
Query Neighborhood Hits	1959	Target Neighborhood Hits	163	Shared Neighborhood Hits	66
SwissProt Accessions	Q96BH1, Q9H874	Gene names	RNF25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-).

GAK2_HUMAN
NC score	0.021136 (rank : 1622)	θ value	1.06291 (rank : 1377)
Query Neighborhood Hits	1959	Target Neighborhood Hits	406	Shared Neighborhood Hits	186
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

FMNL_MOUSE
NC score	0.021132 (rank : 1623)	θ value	8.99809 (rank : 1897)
Query Neighborhood Hits	1959	Target Neighborhood Hits	428	Shared Neighborhood Hits	145
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

PHLPP_MOUSE
NC score	0.021123 (rank : 1624)	θ value	5.27518 (rank : 1772)
Query Neighborhood Hits	1959	Target Neighborhood Hits	394	Shared Neighborhood Hits	93
SwissProt Accessions	Q8CHE4, Q6PCN0, Q8QZU8, Q8R5E5, Q99KL6	Gene names	Phlpp, Kiaa0606, Plekhe1, Scop
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein).

AHTF1_MOUSE
NC score	0.021089 (rank : 1625)	θ value	0.365318 (rank : 1201)
Query Neighborhood Hits	1959	Target Neighborhood Hits	176	Shared Neighborhood Hits	69
SwissProt Accessions	Q8CJF7, Q8BVJ5, Q8VD55	Gene names	Ahctf1, Elys
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

DPOD3_HUMAN
NC score	0.021082 (rank : 1626)	θ value	0.125558 (rank : 1120)
Query Neighborhood Hits	1959	Target Neighborhood Hits	109	Shared Neighborhood Hits	41
SwissProt Accessions	Q15054	Gene names	POLD3, KIAA0039
Domain Architecture	No domain graphic available
Description	DNA polymerase subunit delta 3 (DNA polymerase subunit delta p66).

GA2L1_HUMAN
NC score	0.020968 (rank : 1627)	θ value	1.06291 (rank : 1375)
Query Neighborhood Hits	1959	Target Neighborhood Hits	177	Shared Neighborhood Hits	67
SwissProt Accessions	Q99501, Q53EN7, Q92640, Q9BUY9	Gene names	GAS2L1, GAR22
Domain Architecture
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1) (GAS2-related protein on chromosome 22) (GAR22 protein).

DIAP1_HUMAN
NC score	0.020966 (rank : 1628)	θ value	1.06291 (rank : 1369)
Query Neighborhood Hits	1959	Target Neighborhood Hits	784	Shared Neighborhood Hits	181
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

PDLI7_HUMAN
NC score	0.020940 (rank : 1629)	θ value	0.279714 (rank : 1191)
Query Neighborhood Hits	1959	Target Neighborhood Hits	547	Shared Neighborhood Hits	193
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

DIAP1_MOUSE
NC score	0.020910 (rank : 1630)	θ value	2.36792 (rank : 1531)
Query Neighborhood Hits	1959	Target Neighborhood Hits	839	Shared Neighborhood Hits	172
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

YETS2_MOUSE
NC score	0.020847 (rank : 1631)	θ value	3.0926 (rank : 1629)
Query Neighborhood Hits	1959	Target Neighborhood Hits	278	Shared Neighborhood Hits	106
SwissProt Accessions	Q3TUF7, Q6PGF8, Q80TI2, Q8CG86	Gene names	Yeats2, Kiaa1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

PRGC2_MOUSE
NC score	0.020805 (rank : 1632)	θ value	0.21417 (rank : 1167)
Query Neighborhood Hits	1959	Target Neighborhood Hits	225	Shared Neighborhood Hits	67
SwissProt Accessions	Q8VHJ7, Q8C1C0	Gene names	Ppargc1b, Errl1, Pgc1, Pgc1b, Ppargc1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta protein) (PGC-1beta) (ERR ligand 1) (PPARGC-1-beta) (PGC-1-beta).

MED12_HUMAN
NC score	0.020740 (rank : 1633)	θ value	3.0926 (rank : 1603)
Query Neighborhood Hits	1959	Target Neighborhood Hits	262	Shared Neighborhood Hits	63
SwissProt Accessions	Q93074, O15410, O75557, Q9UHV6, Q9UND7	Gene names	MED12, ARC240, CAGH45, HOPA, KIAA0192, TNRC11, TRAP230
Domain Architecture	No domain graphic available
Description	Mediator of RNA polymerase II transcription subunit 12 (Thyroid hormone receptor-associated protein complex 230 kDa component) (Trap230) (Activator-recruited cofactor 240 kDa component) (ARC240) (CAG repeat protein 45) (OPA-containing protein) (Trinucleotide repeat-containing gene 11 protein).

NSD1_HUMAN
NC score	0.020713 (rank : 1634)	θ value	0.163984 (rank : 1139)
Query Neighborhood Hits	1959	Target Neighborhood Hits	427	Shared Neighborhood Hits	144
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

PCX3_MOUSE
NC score	0.020676 (rank : 1635)	θ value	1.06291 (rank : 1396)
Query Neighborhood Hits	1959	Target Neighborhood Hits	134	Shared Neighborhood Hits	63
SwissProt Accessions	Q8VI59	Gene names	Pcnxl3
Domain Architecture
Description	Pecanex-like protein 3.

ES8L1_MOUSE
NC score	0.020673 (rank : 1636)	θ value	1.81305 (rank : 1481)
Query Neighborhood Hits	1959	Target Neighborhood Hits	143	Shared Neighborhood Hits	45
SwissProt Accessions	Q8R5F8, Q8R0D6, Q9D2M6	Gene names	Eps8l1, Eps8r1
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 1 (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-like protein 1).

SNIP_HUMAN
NC score	0.020658 (rank : 1637)	θ value	8.99809 (rank : 1940)
Query Neighborhood Hits	1959	Target Neighborhood Hits	313	Shared Neighborhood Hits	93
SwissProt Accessions	Q9C0H9, Q8N4W8	Gene names	P140, KIAA1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

MOR2A_MOUSE
NC score	0.020439 (rank : 1638)	θ value	0.0193708 (rank : 1018)
Query Neighborhood Hits	1959	Target Neighborhood Hits	220	Shared Neighborhood Hits	70
SwissProt Accessions	Q69ZX6, Q5QNQ7, Q6P547	Gene names	Morc2a, Kiaa0852, Zcwcc1
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 2A (Zinc finger CW-type coiled-coil domain protein 1).

FBSH_MOUSE
NC score	0.020410 (rank : 1639)	θ value	0.47712 (rank : 1250)
Query Neighborhood Hits	1959	Target Neighborhood Hits	52	Shared Neighborhood Hits	28
SwissProt Accessions	Q8R089	Gene names	Fbs1, Fbs
Domain Architecture	No domain graphic available
Description	Probable fibrosin-1 long transcript protein.

MAML2_HUMAN
NC score	0.020389 (rank : 1640)	θ value	5.27518 (rank : 1758)
Query Neighborhood Hits	1959	Target Neighborhood Hits	360	Shared Neighborhood Hits	98
SwissProt Accessions	Q8IZL2, Q6AI23, Q6Y3A3, Q8IUL3, Q96JK6	Gene names	MAML2, KIAA1819
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 2 (Mam-2).

LDB3_MOUSE
NC score	0.020106 (rank : 1641)	θ value	0.47712 (rank : 1261)
Query Neighborhood Hits	1959	Target Neighborhood Hits	510	Shared Neighborhood Hits	171
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

ARHGF_HUMAN
NC score	0.019965 (rank : 1642)	θ value	4.03905 (rank : 1634)
Query Neighborhood Hits	1959	Target Neighborhood Hits	214	Shared Neighborhood Hits	92
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

NRX2B_HUMAN
NC score	0.019795 (rank : 1643)	θ value	6.88961 (rank : 1838)
Query Neighborhood Hits	1959	Target Neighborhood Hits	481	Shared Neighborhood Hits	178
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

LSM11_HUMAN
NC score	0.019738 (rank : 1644)	θ value	0.813845 (rank : 1335)
Query Neighborhood Hits	1959	Target Neighborhood Hits	16	Shared Neighborhood Hits	6
SwissProt Accessions	P83369, Q7Z7P0, Q8N975	Gene names	LSM11
Domain Architecture	No domain graphic available
Description	U7 snRNA-associated Sm-like protein LSm11.

SEPT9_MOUSE
NC score	0.019679 (rank : 1645)	θ value	0.0563607 (rank : 1078)
Query Neighborhood Hits	1959	Target Neighborhood Hits	238	Shared Neighborhood Hits	91
SwissProt Accessions	Q80UG5, Q3URP2, Q80TM7, Q9QYX9	Gene names	Sept9, Kiaa0991, Sint1
Domain Architecture	No domain graphic available
Description	Septin-9 (SL3-3 integration site 1 protein).

CUTL1_HUMAN
NC score	0.019639 (rank : 1646)	θ value	5.27518 (rank : 1728)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1574	Shared Neighborhood Hits	269
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

GAK12_HUMAN
NC score	0.019548 (rank : 1647)	θ value	0.813845 (rank : 1328)
Query Neighborhood Hits	1959	Target Neighborhood Hits	374	Shared Neighborhood Hits	169
SwissProt Accessions	P63130, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K102 Gag protein) (HERV-K(III) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

TJAP1_MOUSE
NC score	0.019430 (rank : 1648)	θ value	0.47712 (rank : 1274)
Query Neighborhood Hits	1959	Target Neighborhood Hits	295	Shared Neighborhood Hits	51
SwissProt Accessions	Q9DCD5, Q8CFL7, Q8R5I2	Gene names	Tjap1, Pilt, Tjp4
Domain Architecture	No domain graphic available
Description	Tight junction-associated protein 1 (Tight junction protein 4) (Protein incorporated later into tight junctions).

EP400_HUMAN
NC score	0.019293 (rank : 1649)	θ value	5.27518 (rank : 1736)
Query Neighborhood Hits	1959	Target Neighborhood Hits	556	Shared Neighborhood Hits	213
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

JIP2_MOUSE
NC score	0.019133 (rank : 1650)	θ value	1.06291 (rank : 1385)
Query Neighborhood Hits	1959	Target Neighborhood Hits	144	Shared Neighborhood Hits	40
SwissProt Accessions	Q9ERE9, Q9CXI4	Gene names	Mapk8ip2, Ib2, Jip2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

PRR6_HUMAN
NC score	0.019128 (rank : 1651)	θ value	0.279714 (rank : 1192)
Query Neighborhood Hits	1959	Target Neighborhood Hits	39	Shared Neighborhood Hits	25
SwissProt Accessions	Q7Z7K6, Q3L8N5, Q8NFH6	Gene names	PRR6
Domain Architecture	No domain graphic available
Description	Proline-rich protein 6 (Nuclear protein p30).

ZN598_HUMAN
NC score	0.019107 (rank : 1652)	θ value	4.03905 (rank : 1704)
Query Neighborhood Hits	1959	Target Neighborhood Hits	339	Shared Neighborhood Hits	89
SwissProt Accessions	Q86UK7, Q8IW49, Q8N3D9, Q96FG3, Q9H7J3	Gene names	ZNF598
Domain Architecture	No domain graphic available
Description	Zinc finger protein 598.

ESPL1_MOUSE
NC score	0.019052 (rank : 1653)	θ value	0.0252991 (rank : 1027)
Query Neighborhood Hits	1959	Target Neighborhood Hits	67	Shared Neighborhood Hits	13
SwissProt Accessions	P60330	Gene names	Espl1, Esp1, Kiaa0165
Domain Architecture
Description	Separin (EC 3.4.22.49) (Separase) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein).

NUMBL_HUMAN
NC score	0.018961 (rank : 1654)	θ value	6.88961 (rank : 1839)
Query Neighborhood Hits	1959	Target Neighborhood Hits	394	Shared Neighborhood Hits	167
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

NRX2A_HUMAN
NC score	0.018896 (rank : 1655)	θ value	6.88961 (rank : 1837)
Query Neighborhood Hits	1959	Target Neighborhood Hits	614	Shared Neighborhood Hits	191
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

HCN4_HUMAN
NC score	0.018841 (rank : 1656)	θ value	5.27518 (rank : 1744)
Query Neighborhood Hits	1959	Target Neighborhood Hits	303	Shared Neighborhood Hits	132
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

PLCB3_HUMAN
NC score	0.018802 (rank : 1657)	θ value	1.81305 (rank : 1506)
Query Neighborhood Hits	1959	Target Neighborhood Hits	445	Shared Neighborhood Hits	72
SwissProt Accessions	Q01970	Gene names	PLCB3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

UBP42_HUMAN
NC score	0.018802 (rank : 1658)	θ value	0.00869519 (rank : 997)
Query Neighborhood Hits	1959	Target Neighborhood Hits	445	Shared Neighborhood Hits	153
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

DNL1_HUMAN
NC score	0.018799 (rank : 1659)	θ value	4.03905 (rank : 1651)
Query Neighborhood Hits	1959	Target Neighborhood Hits	216	Shared Neighborhood Hits	81
SwissProt Accessions	P18858	Gene names	LIG1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

LAP4_HUMAN
NC score	0.018712 (rank : 1660)	θ value	5.27518 (rank : 1754)
Query Neighborhood Hits	1959	Target Neighborhood Hits	608	Shared Neighborhood Hits	129
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

FILA_HUMAN
NC score	0.018640 (rank : 1661)	θ value	6.88961 (rank : 1820)
Query Neighborhood Hits	1959	Target Neighborhood Hits	685	Shared Neighborhood Hits	144
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

PRCC_HUMAN
NC score	0.018635 (rank : 1662)	θ value	8.99809 (rank : 1930)
Query Neighborhood Hits	1959	Target Neighborhood Hits	109	Shared Neighborhood Hits	55
SwissProt Accessions	Q92733, O00665, O00724	Gene names	PRCC, TPRC
Domain Architecture	No domain graphic available
Description	Proline-rich protein PRCC (Papillary renal cell carcinoma translocation-associated gene protein).

TJAP1_HUMAN
NC score	0.018489 (rank : 1663)	θ value	0.365318 (rank : 1240)
Query Neighborhood Hits	1959	Target Neighborhood Hits	214	Shared Neighborhood Hits	43
SwissProt Accessions	Q5JTD0, Q5JTD1, Q5JWW1, Q68DB2, Q6P2P3, Q9H7V7	Gene names	TJAP1, PILT, TJP4
Domain Architecture	No domain graphic available
Description	Tight junction-associated protein 1 (Tight junction protein 4) (Protein incorporated later into tight junctions).

SNPC4_MOUSE
NC score	0.018393 (rank : 1664)	θ value	3.0926 (rank : 1620)
Query Neighborhood Hits	1959	Target Neighborhood Hits	237	Shared Neighborhood Hits	94
SwissProt Accessions	Q8BP86, Q6PGG7, Q80UG9, Q810L1	Gene names	Snapc4
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit).

ETV3_HUMAN
NC score	0.018192 (rank : 1665)	θ value	0.365318 (rank : 1210)
Query Neighborhood Hits	1959	Target Neighborhood Hits	312	Shared Neighborhood Hits	122
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

ZO1_HUMAN
NC score	0.018127 (rank : 1666)	θ value	5.27518 (rank : 1793)
Query Neighborhood Hits	1959	Target Neighborhood Hits	474	Shared Neighborhood Hits	163
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

DPOD3_MOUSE
NC score	0.018027 (rank : 1667)	θ value	4.03905 (rank : 1652)
Query Neighborhood Hits	1959	Target Neighborhood Hits	118	Shared Neighborhood Hits	49
SwissProt Accessions	Q9EQ28	Gene names	Pold3
Domain Architecture	No domain graphic available
Description	DNA polymerase subunit delta 3 (DNA polymerase subunit delta p66).

LDB3_HUMAN
NC score	0.017951 (rank : 1668)	θ value	4.03905 (rank : 1667)
Query Neighborhood Hits	1959	Target Neighborhood Hits	497	Shared Neighborhood Hits	154
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

TAB3_MOUSE
NC score	0.017921 (rank : 1669)	θ value	8.99809 (rank : 1943)
Query Neighborhood Hits	1959	Target Neighborhood Hits	273	Shared Neighborhood Hits	118
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

HN1L_HUMAN
NC score	0.017790 (rank : 1670)	θ value	2.36792 (rank : 1538)
Query Neighborhood Hits	1959	Target Neighborhood Hits	88	Shared Neighborhood Hits	54
SwissProt Accessions	Q9H910, Q6EIC7	Gene names	C16orf34, HN1L
Domain Architecture	No domain graphic available
Description	Hematological and neurological expressed 1-like protein (HN1-like protein).

GAK10_HUMAN
NC score	0.017656 (rank : 1671)	θ value	6.88961 (rank : 1823)
Query Neighborhood Hits	1959	Target Neighborhood Hits	289	Shared Neighborhood Hits	136
SwissProt Accessions	P87889, P10263, P10264, Q69385, Q9UKH6	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q33.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K10 Gag protein) (HERV-K107 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

K0423_HUMAN
NC score	0.017613 (rank : 1672)	θ value	0.21417 (rank : 1158)
Query Neighborhood Hits	1959	Target Neighborhood Hits	171	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y4F4, Q68D66, Q6PG27	Gene names	KIAA0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

MAML1_HUMAN
NC score	0.017596 (rank : 1673)	θ value	1.81305 (rank : 1500)
Query Neighborhood Hits	1959	Target Neighborhood Hits	228	Shared Neighborhood Hits	93
SwissProt Accessions	Q92585, Q9NZ12	Gene names	MAML1, KIAA0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

IRS1_MOUSE
NC score	0.017557 (rank : 1674)	θ value	1.06291 (rank : 1383)
Query Neighborhood Hits	1959	Target Neighborhood Hits	112	Shared Neighborhood Hits	48
SwissProt Accessions	P35569	Gene names	Irs1, Irs-1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

NFAC1_HUMAN
NC score	0.017542 (rank : 1675)	θ value	0.813845 (rank : 1337)
Query Neighborhood Hits	1959	Target Neighborhood Hits	312	Shared Neighborhood Hits	146
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

LZTS2_MOUSE
NC score	0.017513 (rank : 1676)	θ value	0.21417 (rank : 1162)
Query Neighborhood Hits	1959	Target Neighborhood Hits	423	Shared Neighborhood Hits	71
SwissProt Accessions	Q91YU6, Q569X6	Gene names	Lzts2, Kiaa1813
Domain Architecture
Description	Leucine zipper putative tumor suppressor 2.

RIMS2_HUMAN
NC score	0.017506 (rank : 1677)	θ value	6.88961 (rank : 1844)
Query Neighborhood Hits	1959	Target Neighborhood Hits	342	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

RUSC1_HUMAN
NC score	0.017483 (rank : 1678)	θ value	4.03905 (rank : 1690)
Query Neighborhood Hits	1959	Target Neighborhood Hits	226	Shared Neighborhood Hits	71
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

DOS_HUMAN
NC score	0.017466 (rank : 1679)	θ value	0.62314 (rank : 1288)
Query Neighborhood Hits	1959	Target Neighborhood Hits	68	Shared Neighborhood Hits	26
SwissProt Accessions	Q8N350, O43385	Gene names	DOS, C19orf26
Domain Architecture	No domain graphic available
Description	Protein Dos.

OBF1_MOUSE
NC score	0.017445 (rank : 1680)	θ value	5.27518 (rank : 1769)
Query Neighborhood Hits	1959	Target Neighborhood Hits	73	Shared Neighborhood Hits	40
SwissProt Accessions	Q64693	Gene names	Pou2af1, Obf-1
Domain Architecture	No domain graphic available
Description	POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (OCT-binding factor 1) (BOB-1) (BOB1) (OCA-B).

IQEC2_MOUSE
NC score	0.017398 (rank : 1681)	θ value	1.81305 (rank : 1494)
Query Neighborhood Hits	1959	Target Neighborhood Hits	417	Shared Neighborhood Hits	157
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

DYN1_HUMAN
NC score	0.017356 (rank : 1682)	θ value	3.0926 (rank : 1586)
Query Neighborhood Hits	1959	Target Neighborhood Hits	216	Shared Neighborhood Hits	104
SwissProt Accessions	Q05193	Gene names	DNM1, DNM
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

PLCB1_HUMAN
NC score	0.017112 (rank : 1683)	θ value	4.03905 (rank : 1680)
Query Neighborhood Hits	1959	Target Neighborhood Hits	614	Shared Neighborhood Hits	105
SwissProt Accessions	Q9NQ66, O60325, Q5TFF7, Q5TGC9, Q8IV93, Q9BQW2, Q9H4H2, Q9H8H5, Q9NQ65, Q9NQH9, Q9NTH4, Q9UJP6, Q9UM26	Gene names	PLCB1, KIAA0581
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

PRLR_HUMAN
NC score	0.017084 (rank : 1684)	θ value	0.813845 (rank : 1342)
Query Neighborhood Hits	1959	Target Neighborhood Hits	95	Shared Neighborhood Hits	33
SwissProt Accessions	P16471, Q16354, Q9BX87	Gene names	PRLR
Domain Architecture
Description	Prolactin receptor precursor (PRL-R).

IQEC2_HUMAN
NC score	0.017063 (rank : 1685)	θ value	1.81305 (rank : 1493)
Query Neighborhood Hits	1959	Target Neighborhood Hits	403	Shared Neighborhood Hits	156
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

ZYX_MOUSE
NC score	0.017030 (rank : 1686)	θ value	5.27518 (rank : 1794)
Query Neighborhood Hits	1959	Target Neighborhood Hits	347	Shared Neighborhood Hits	114
SwissProt Accessions	Q62523, P70461	Gene names	Zyx
Domain Architecture
Description	Zyxin.

ZO1_MOUSE
NC score	0.017004 (rank : 1687)	θ value	8.99809 (rank : 1959)
Query Neighborhood Hits	1959	Target Neighborhood Hits	453	Shared Neighborhood Hits	152
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

RANB3_MOUSE
NC score	0.016990 (rank : 1688)	θ value	1.06291 (rank : 1403)
Query Neighborhood Hits	1959	Target Neighborhood Hits	123	Shared Neighborhood Hits	57
SwissProt Accessions	Q9CT10, Q3TIS4, Q3U2G4, Q3UYG7	Gene names	Ranbp3
Domain Architecture	No domain graphic available
Description	Ran-binding protein 3 (RanBP3).

GLU2B_MOUSE
NC score	0.016943 (rank : 1689)	θ value	1.38821 (rank : 1433)
Query Neighborhood Hits	1959	Target Neighborhood Hits	357	Shared Neighborhood Hits	59
SwissProt Accessions	O08795, Q921X2	Gene names	Prkcsh
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

BAZ1A_HUMAN
NC score	0.016909 (rank : 1690)	θ value	5.27518 (rank : 1721)
Query Neighborhood Hits	1959	Target Neighborhood Hits	693	Shared Neighborhood Hits	127
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

K1949_HUMAN
NC score	0.016864 (rank : 1691)	θ value	2.36792 (rank : 1540)
Query Neighborhood Hits	1959	Target Neighborhood Hits	121	Shared Neighborhood Hits	50
SwissProt Accessions	Q6NYC8, Q68CK8, Q6ZUJ6, Q8NDQ4, Q8TF52, Q9BRL9	Gene names	KIAA1949
Domain Architecture	No domain graphic available
Description	Protein KIAA1949.

RUNX2_HUMAN
NC score	0.016864 (rank : 1692)	θ value	0.279714 (rank : 1195)
Query Neighborhood Hits	1959	Target Neighborhood Hits	103	Shared Neighborhood Hits	50
SwissProt Accessions	Q13950, O14614, O14615, O95181	Gene names	RUNX2, AML3, CBFA1, OSF2, PEBP2A
Domain Architecture
Description	Runt-related transcription factor 2 (Core-binding factor, alpha 1 subunit) (CBF-alpha 1) (Acute myeloid leukemia 3 protein) (Oncogene AML-3) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEBP2-alpha A) (PEA2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit) (Osteoblast- specific transcription factor 2) (OSF-2).

TAF6L_MOUSE
NC score	0.016765 (rank : 1693)	θ value	0.62314 (rank : 1307)
Query Neighborhood Hits	1959	Target Neighborhood Hits	146	Shared Neighborhood Hits	71
SwissProt Accessions	Q8R2K4, Q8C5T2	Gene names	Taf6l, Paf65a
Domain Architecture
Description	TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (PCAF-associated factor 65 alpha) (PAF65- alpha).

RBM16_HUMAN
NC score	0.016717 (rank : 1694)	θ value	8.99809 (rank : 1933)
Query Neighborhood Hits	1959	Target Neighborhood Hits	300	Shared Neighborhood Hits	91
SwissProt Accessions	Q9UPN6, Q5TBU6, Q9BQN8, Q9BX43	Gene names	RBM16, KIAA1116
Domain Architecture
Description	Putative RNA-binding protein 16 (RNA-binding motif protein 16).

CS021_HUMAN
NC score	0.016578 (rank : 1695)	θ value	5.27518 (rank : 1727)
Query Neighborhood Hits	1959	Target Neighborhood Hits	98	Shared Neighborhood Hits	52
SwissProt Accessions	Q8IVT2	Gene names	C19orf21
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf21.

FBSH_HUMAN
NC score	0.016487 (rank : 1696)	θ value	1.81305 (rank : 1482)
Query Neighborhood Hits	1959	Target Neighborhood Hits	46	Shared Neighborhood Hits	26
SwissProt Accessions	Q9HAH7, Q96CI9, Q9H9X4	Gene names	FBS1, FBS
Domain Architecture	No domain graphic available
Description	Probable fibrosin-1 long transcript protein.

MKL2_MOUSE
NC score	0.016166 (rank : 1697)	θ value	1.06291 (rank : 1392)
Query Neighborhood Hits	1959	Target Neighborhood Hits	269	Shared Neighborhood Hits	77
SwissProt Accessions	P59759	Gene names	Mkl2, Mrtfb
Domain Architecture
Description	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B).

FLIP1_HUMAN
NC score	0.016104 (rank : 1698)	θ value	1.81305 (rank : 1483)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1405	Shared Neighborhood Hits	176
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

GORS2_MOUSE
NC score	0.016076 (rank : 1699)	θ value	0.365318 (rank : 1213)
Query Neighborhood Hits	1959	Target Neighborhood Hits	89	Shared Neighborhood Hits	46
SwissProt Accessions	Q99JX3, Q3U9D2, Q8CCD0, Q91W68	Gene names	Gorasp2
Domain Architecture	No domain graphic available
Description	Golgi reassembly-stacking protein 2 (GRS2) (Golgi reassembly-stacking protein of 55 kDa) (GRASP55).

DOK2_MOUSE
NC score	0.016070 (rank : 1700)	θ value	6.88961 (rank : 1814)
Query Neighborhood Hits	1959	Target Neighborhood Hits	244	Shared Neighborhood Hits	112
SwissProt Accessions	O70469, O70272, Q99KL1	Gene names	Dok2, Frip
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)) (Dok- related protein) (Dok-R) (IL-four receptor-interacting protein) (FRIP).

NOL3_MOUSE
NC score	0.016042 (rank : 1701)	θ value	8.99809 (rank : 1923)
Query Neighborhood Hits	1959	Target Neighborhood Hits	97	Shared Neighborhood Hits	40
SwissProt Accessions	Q9D1X0	Gene names	Nol3
Domain Architecture
Description	Nucleolar protein 3.

CT055_MOUSE
NC score	0.015969 (rank : 1702)	θ value	2.36792 (rank : 1529)
Query Neighborhood Hits	1959	Target Neighborhood Hits	52	Shared Neighborhood Hits	33
SwissProt Accessions	Q8R184, Q8BQE5, Q8K024, Q8VEM7, Q9CU80	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf55 homolog.

AF17_HUMAN
NC score	0.015928 (rank : 1703)	θ value	1.38821 (rank : 1422)
Query Neighborhood Hits	1959	Target Neighborhood Hits	230	Shared Neighborhood Hits	84
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

LRRF1_HUMAN
NC score	0.015788 (rank : 1704)	θ value	1.06291 (rank : 1388)
Query Neighborhood Hits	1959	Target Neighborhood Hits	625	Shared Neighborhood Hits	88
SwissProt Accessions	Q32MZ4, O75766, O75799, Q32MZ5, Q53T49, Q6PKG2	Gene names	LRRFIP1, GCF2, TRIP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (TAR RNA-interacting protein) (GC-binding factor 2).

RUNX2_MOUSE
NC score	0.015767 (rank : 1705)	θ value	0.279714 (rank : 1196)
Query Neighborhood Hits	1959	Target Neighborhood Hits	119	Shared Neighborhood Hits	54
SwissProt Accessions	Q08775, O35183, Q08776, Q9JLN0, Q9QUQ6, Q9QY29, Q9R0U4, Q9Z2J7	Gene names	Runx2, Aml3, Cbfa1, Osf2, Pebp2a
Domain Architecture
Description	Runt-related transcription factor 2 (Core-binding factor, alpha 1 subunit) (CBF-alpha 1) (Acute myeloid leukemia 3 protein) (Oncogene AML-3) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEBP2-alpha A) (PEA2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit) (Osteoblast- specific transcription factor 2) (OSF-2).

SETD2_HUMAN
NC score	0.015716 (rank : 1706)	θ value	2.36792 (rank : 1563)
Query Neighborhood Hits	1959	Target Neighborhood Hits	412	Shared Neighborhood Hits	103
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

CP007_MOUSE
NC score	0.015682 (rank : 1707)	θ value	4.03905 (rank : 1647)
Query Neighborhood Hits	1959	Target Neighborhood Hits	231	Shared Neighborhood Hits	78
SwissProt Accessions	Q8C190, Q6PFD1	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf7 homolog (5-day ovary-specific transcript 1 protein).

STAP2_HUMAN
NC score	0.015614 (rank : 1708)	θ value	0.163984 (rank : 1148)
Query Neighborhood Hits	1959	Target Neighborhood Hits	29	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UGK3, Q9NXI2	Gene names	STAP2, BKS
Domain Architecture	No domain graphic available
Description	Signal-transducing adaptor protein 2 (STAP-2) (Breast tumor kinase substrate) (BRK substrate).

RFX1_MOUSE
NC score	0.015582 (rank : 1709)	θ value	5.27518 (rank : 1778)
Query Neighborhood Hits	1959	Target Neighborhood Hits	181	Shared Neighborhood Hits	93
SwissProt Accessions	P48377	Gene names	Rfx1
Domain Architecture
Description	DNA-binding protein RFX1.

NASP_HUMAN
NC score	0.015567 (rank : 1710)	θ value	5.27518 (rank : 1765)
Query Neighborhood Hits	1959	Target Neighborhood Hits	709	Shared Neighborhood Hits	125
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

NCTR2_HUMAN
NC score	0.015561 (rank : 1711)	θ value	5.27518 (rank : 1766)
Query Neighborhood Hits	1959	Target Neighborhood Hits	99	Shared Neighborhood Hits	50
SwissProt Accessions	O95944, Q9H562, Q9H563, Q9H564, Q9UMT1, Q9UMT2	Gene names	NCR2, LY95
Domain Architecture
Description	Natural cytotoxicity triggering receptor 2 precursor (Natural killer cell p44-related protein) (NKp44) (NK-p44) (NK cell-activating receptor) (Lymphocyte antigen 95 homolog) (CD336 antigen).

CCD1A_HUMAN
NC score	0.015479 (rank : 1712)	θ value	3.0926 (rank : 1579)
Query Neighborhood Hits	1959	Target Neighborhood Hits	123	Shared Neighborhood Hits	54
SwissProt Accessions	Q6P1N0, Q7Z435, Q86XV0, Q8NF89, Q9H603, Q9NXI1	Gene names	CC2D1A
Domain Architecture	No domain graphic available
Description	Coiled-coil and C2 domain-containing protein 1A (Five repressor element under dual repression-binding protein 1) (FRE under dual repression-binding protein 1) (Freud-1) (Putative NF-kappa-B- activating protein 023N).

SYNJ2_HUMAN
NC score	0.015330 (rank : 1713)	θ value	4.03905 (rank : 1696)
Query Neighborhood Hits	1959	Target Neighborhood Hits	136	Shared Neighborhood Hits	68
SwissProt Accessions	O15056, Q5TA13, Q5TA16, Q5TA19, Q86XK0, Q8IZA8, Q9H226	Gene names	SYNJ2, KIAA0348
Domain Architecture	No domain graphic available
Description	Synaptojanin-2 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 2).

SIN3A_HUMAN
NC score	0.015266 (rank : 1714)	θ value	3.0926 (rank : 1616)
Query Neighborhood Hits	1959	Target Neighborhood Hits	180	Shared Neighborhood Hits	87
SwissProt Accessions	Q96ST3, Q8N8N4, Q8NC83, Q8WV18, Q96L98, Q9UFQ1	Gene names	SIN3A
Domain Architecture
Description	Paired amphipathic helix protein Sin3a (Transcriptional corepressor Sin3a) (Histone deacetylase complex subunit Sin3a).

RECQ5_HUMAN
NC score	0.015181 (rank : 1715)	θ value	8.99809 (rank : 1934)
Query Neighborhood Hits	1959	Target Neighborhood Hits	390	Shared Neighborhood Hits	152
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

FGD1_MOUSE
NC score	0.015160 (rank : 1716)	θ value	6.88961 (rank : 1819)
Query Neighborhood Hits	1959	Target Neighborhood Hits	387	Shared Neighborhood Hits	127
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

BAG4_MOUSE
NC score	0.015124 (rank : 1717)	θ value	8.99809 (rank : 1868)
Query Neighborhood Hits	1959	Target Neighborhood Hits	79	Shared Neighborhood Hits	37
SwissProt Accessions	Q8CI61, Q3TRL9, Q91VT5, Q9CWG2	Gene names	Bag4, Sodd
Domain Architecture
Description	BAG family molecular chaperone regulator 4 (BCL2-associated athanogene 4) (BAG-4) (Silencer of death domains).

CUTL2_MOUSE
NC score	0.014911 (rank : 1718)	θ value	1.81305 (rank : 1477)
Query Neighborhood Hits	1959	Target Neighborhood Hits	771	Shared Neighborhood Hits	144
SwissProt Accessions	P70298	Gene names	Cutl2
Domain Architecture
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

EHMT2_MOUSE
NC score	0.014815 (rank : 1719)	θ value	2.36792 (rank : 1532)
Query Neighborhood Hits	1959	Target Neighborhood Hits	750	Shared Neighborhood Hits	195
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

H13_MOUSE
NC score	0.014782 (rank : 1720)	θ value	0.47712 (rank : 1255)
Query Neighborhood Hits	1959	Target Neighborhood Hits	81	Shared Neighborhood Hits	36
SwissProt Accessions	P43277, Q8C6M4	Gene names	Hist1h1d, H1f3
Domain Architecture
Description	Histone H1.3 (H1 VAR.4) (H1d).

NFM_HUMAN
NC score	0.014580 (rank : 1721)	θ value	1.06291 (rank : 1395)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1328	Shared Neighborhood Hits	241
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

MAGD4_HUMAN
NC score	0.014537 (rank : 1722)	θ value	2.36792 (rank : 1546)
Query Neighborhood Hits	1959	Target Neighborhood Hits	338	Shared Neighborhood Hits	160
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

NUMA1_HUMAN
NC score	0.014515 (rank : 1723)	θ value	0.279714 (rank : 1190)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1523	Shared Neighborhood Hits	177
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

IF4G3_MOUSE
NC score	0.014467 (rank : 1724)	θ value	0.279714 (rank : 1181)
Query Neighborhood Hits	1959	Target Neighborhood Hits	279	Shared Neighborhood Hits	83
SwissProt Accessions	Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0	Gene names	Eif4g3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

CBL_HUMAN
NC score	0.014362 (rank : 1725)	θ value	0.62314 (rank : 1286)
Query Neighborhood Hits	1959	Target Neighborhood Hits	353	Shared Neighborhood Hits	96
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

SIN3A_MOUSE
NC score	0.014136 (rank : 1726)	θ value	1.06291 (rank : 1410)
Query Neighborhood Hits	1959	Target Neighborhood Hits	169	Shared Neighborhood Hits	71
SwissProt Accessions	Q60520, Q60820, Q62139, Q62140, Q7TPU8, Q7TSZ2	Gene names	Sin3a
Domain Architecture
Description	Paired amphipathic helix protein Sin3a (Transcriptional corepressor Sin3a) (Histone deacetylase complex subunit Sin3a).

RANB3_HUMAN
NC score	0.014084 (rank : 1727)	θ value	2.36792 (rank : 1560)
Query Neighborhood Hits	1959	Target Neighborhood Hits	117	Shared Neighborhood Hits	46
SwissProt Accessions	Q9H6Z4, O60405, O75759, O75760, Q9BT47, Q9UG74	Gene names	RANBP3
Domain Architecture	No domain graphic available
Description	Ran-binding protein 3 (RanBP3).

ANK3_HUMAN
NC score	0.014053 (rank : 1728)	θ value	1.06291 (rank : 1356)
Query Neighborhood Hits	1959	Target Neighborhood Hits	853	Shared Neighborhood Hits	174
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

ZIMP7_HUMAN
NC score	0.014034 (rank : 1729)	θ value	0.21417 (rank : 1173)
Query Neighborhood Hits	1959	Target Neighborhood Hits	290	Shared Neighborhood Hits	91
SwissProt Accessions	Q8NF64, O94790, Q659A8, Q6JKL5, Q8WTX8, Q96Q01, Q9BQH7	Gene names	ZIMP7, KIAA1886
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

UBQL3_HUMAN
NC score	0.014000 (rank : 1730)	θ value	0.0961366 (rank : 1111)
Query Neighborhood Hits	1959	Target Neighborhood Hits	141	Shared Neighborhood Hits	53
SwissProt Accessions	Q9H347, Q9NRE0	Gene names	UBQLN3
Domain Architecture
Description	Ubiquilin-3.

PKHA4_MOUSE
NC score	0.013996 (rank : 1731)	θ value	0.21417 (rank : 1166)
Query Neighborhood Hits	1959	Target Neighborhood Hits	202	Shared Neighborhood Hits	66
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

YAP1_HUMAN
NC score	0.013977 (rank : 1732)	θ value	4.03905 (rank : 1702)
Query Neighborhood Hits	1959	Target Neighborhood Hits	173	Shared Neighborhood Hits	69
SwissProt Accessions	P46937	Gene names	YAP1, YAP65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

ZC3H3_HUMAN
NC score	0.013867 (rank : 1733)	θ value	0.279714 (rank : 1199)
Query Neighborhood Hits	1959	Target Neighborhood Hits	159	Shared Neighborhood Hits	53
SwissProt Accessions	Q8IXZ2, Q14163, Q8N4E2, Q9BUS4	Gene names	ZC3H3, KIAA0150, ZC3HDC3
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

UBN1_HUMAN
NC score	0.013866 (rank : 1734)	θ value	8.99809 (rank : 1951)
Query Neighborhood Hits	1959	Target Neighborhood Hits	170	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NPG3, Q13079, Q9P1P7	Gene names	UBN1
Domain Architecture	No domain graphic available
Description	Ubinuclein (Ubiquitously expressed nuclear protein) (VT4).

DCP1A_MOUSE
NC score	0.013734 (rank : 1735)	θ value	8.99809 (rank : 1892)
Query Neighborhood Hits	1959	Target Neighborhood Hits	103	Shared Neighborhood Hits	50
SwissProt Accessions	Q91YD3, Q6NZE3	Gene names	Dcp1a, Mitc1, Smif
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (MAD homolog 4-interacting transcription coactivator 1) (Smad4-interacting transcriptional co-activator).

GOGA3_HUMAN
NC score	0.013728 (rank : 1736)	θ value	3.0926 (rank : 1590)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1317	Shared Neighborhood Hits	169
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

NOL1_HUMAN
NC score	0.013714 (rank : 1737)	θ value	2.36792 (rank : 1549)
Query Neighborhood Hits	1959	Target Neighborhood Hits	74	Shared Neighborhood Hits	23
SwissProt Accessions	P46087	Gene names	NOL1
Domain Architecture
Description	Proliferating-cell nucleolar antigen p120 (Proliferation-associated nucleolar protein p120).

IF16_HUMAN
NC score	0.013676 (rank : 1738)	θ value	4.03905 (rank : 1662)
Query Neighborhood Hits	1959	Target Neighborhood Hits	182	Shared Neighborhood Hits	85
SwissProt Accessions	Q16666, Q9UH78	Gene names	IFI16, IFNGIP1
Domain Architecture
Description	Gamma-interferon-inducible protein Ifi-16 (Interferon-inducible myeloid differentiation transcriptional activator) (IFI 16).

TOIP1_HUMAN
NC score	0.013472 (rank : 1739)	θ value	1.81305 (rank : 1515)
Query Neighborhood Hits	1959	Target Neighborhood Hits	58	Shared Neighborhood Hits	20
SwissProt Accessions	Q5JTV8, Q5JTV6, Q8IZ65, Q9H8Y6, Q9HAJ1, Q9NV52, Q9Y3X5	Gene names	TOR1AIP1
Domain Architecture	No domain graphic available
Description	Torsin-1A-interacting protein 1.

PHXR5_MOUSE
NC score	0.013301 (rank : 1740)	θ value	4.03905 (rank : 1678)
Query Neighborhood Hits	1959	Target Neighborhood Hits	102	Shared Neighborhood Hits	12
SwissProt Accessions	P08399	Gene names	Phxr5, Per
Domain Architecture	No domain graphic available
Description	Per-hexamer repeat protein 5.

LRCH4_HUMAN
NC score	0.013250 (rank : 1741)	θ value	1.81305 (rank : 1498)
Query Neighborhood Hits	1959	Target Neighborhood Hits	305	Shared Neighborhood Hits	58
SwissProt Accessions	O75427, Q8WV85, Q96ID0	Gene names	LRCH4, LRN, LRRN4
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 4 (Leucine-rich neuronal protein).

CO3A1_HUMAN
NC score	0.013199 (rank : 1742)	θ value	6.88961 (rank : 1803)
Query Neighborhood Hits	1959	Target Neighborhood Hits	452	Shared Neighborhood Hits	152
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CU087_HUMAN
NC score	0.013007 (rank : 1743)	θ value	4.03905 (rank : 1648)
Query Neighborhood Hits	1959	Target Neighborhood Hits	26	Shared Neighborhood Hits	16
SwissProt Accessions	P59051	Gene names	C21orf87
Domain Architecture	No domain graphic available
Description	Protein C21orf87.

U2AFM_MOUSE
NC score	0.012817 (rank : 1744)	θ value	8.99809 (rank : 1950)
Query Neighborhood Hits	1959	Target Neighborhood Hits	543	Shared Neighborhood Hits	68
SwissProt Accessions	Q62377	Gene names	Zrsr2, U2af1-rs2, U2af1l2, U2af1rs2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2).

IRS1_HUMAN
NC score	0.012809 (rank : 1745)	θ value	1.81305 (rank : 1495)
Query Neighborhood Hits	1959	Target Neighborhood Hits	109	Shared Neighborhood Hits	39
SwissProt Accessions	P35568	Gene names	IRS1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

ATF2_HUMAN
NC score	0.012796 (rank : 1746)	θ value	5.27518 (rank : 1715)
Query Neighborhood Hits	1959	Target Neighborhood Hits	402	Shared Neighborhood Hits	104
SwissProt Accessions	P15336, Q13000	Gene names	ATF2, CREB2, CREBP1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (HB16).

WAPL_HUMAN
NC score	0.012732 (rank : 1747)	θ value	1.06291 (rank : 1416)
Query Neighborhood Hits	1959	Target Neighborhood Hits	122	Shared Neighborhood Hits	26
SwissProt Accessions	Q7Z5K2, Q5VSK5, Q8IX10, Q92549	Gene names	WAPAL, FOE, KIAA0261, WAPL
Domain Architecture	No domain graphic available
Description	Wings apart-like protein homolog (Friend of EBNA2 protein).

PO6F1_MOUSE
NC score	0.012716 (rank : 1748)	θ value	0.0563607 (rank : 1077)
Query Neighborhood Hits	1959	Target Neighborhood Hits	581	Shared Neighborhood Hits	159
SwissProt Accessions	Q07916, Q91XK3	Gene names	Pou6f1, Emb
Domain Architecture
Description	POU domain, class 6, transcription factor 1 (Octamer-binding transcription factor EMB) (Transcription regulatory protein MCP-1).

K0423_MOUSE
NC score	0.012686 (rank : 1749)	θ value	0.62314 (rank : 1296)
Query Neighborhood Hits	1959	Target Neighborhood Hits	115	Shared Neighborhood Hits	27
SwissProt Accessions	Q6A070	Gene names	Kiaa0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

BAI1_HUMAN
NC score	0.012628 (rank : 1750)	θ value	5.27518 (rank : 1718)
Query Neighborhood Hits	1959	Target Neighborhood Hits	375	Shared Neighborhood Hits	122
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

DOK7_MOUSE
NC score	0.012572 (rank : 1751)	θ value	5.27518 (rank : 1732)
Query Neighborhood Hits	1959	Target Neighborhood Hits	169	Shared Neighborhood Hits	76
SwissProt Accessions	Q18PE0, Q3TCZ6, Q5FW70, Q8C8U7	Gene names	Dok7
Domain Architecture	No domain graphic available
Description	Protein Dok-7 (Downstream of tyrosine kinase 7).

LRC41_HUMAN
NC score	0.012502 (rank : 1752)	θ value	3.0926 (rank : 1602)
Query Neighborhood Hits	1959	Target Neighborhood Hits	51	Shared Neighborhood Hits	15
SwissProt Accessions	Q15345, Q71RA8, Q9BSM0	Gene names	LRRC41, MUF1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 41 (Protein Muf1).

TTC28_HUMAN
NC score	0.012462 (rank : 1753)	θ value	1.81305 (rank : 1516)
Query Neighborhood Hits	1959	Target Neighborhood Hits	271	Shared Neighborhood Hits	81
SwissProt Accessions	Q96AY4, O95928, O95929, Q9NTE4, Q9UG31, Q9UGG5, Q9UPV8, Q9Y3S5	Gene names	TTC28, KIAA1043
Domain Architecture
Description	Tetratricopeptide repeat protein 28 (TPR repeat protein 28).

ZO2_MOUSE
NC score	0.012448 (rank : 1754)	θ value	1.81305 (rank : 1519)
Query Neighborhood Hits	1959	Target Neighborhood Hits	296	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

DYN1_MOUSE
NC score	0.012343 (rank : 1755)	θ value	3.0926 (rank : 1587)
Query Neighborhood Hits	1959	Target Neighborhood Hits	168	Shared Neighborhood Hits	73
SwissProt Accessions	P39053, Q61358, Q61359, Q61360, Q8JZZ4, Q9CSY7, Q9QXX1	Gene names	Dnm1, Dnm
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

JPH3_HUMAN
NC score	0.012290 (rank : 1756)	θ value	0.21417 (rank : 1157)
Query Neighborhood Hits	1959	Target Neighborhood Hits	80	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WXH2, Q8N471, Q9HDC3, Q9HDC4	Gene names	JPH3, JP3
Domain Architecture
Description	Junctophilin-3 (Junctophilin type 3) (JP-3).

LRC41_MOUSE
NC score	0.012212 (rank : 1757)	θ value	0.279714 (rank : 1186)
Query Neighborhood Hits	1959	Target Neighborhood Hits	37	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K1C9, Q91VX4	Gene names	Lrrc41, Muf1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 41 (Protein Muf1).

EI2BD_HUMAN
NC score	0.012097 (rank : 1758)	θ value	1.06291 (rank : 1371)
Query Neighborhood Hits	1959	Target Neighborhood Hits	34	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UI10, Q5BJF4, Q9BUV9, Q9UBG4, Q9UIQ9, Q9UJ95	Gene names	EIF2B4, EIF2BD
Domain Architecture
Description	Translation initiation factor eIF-2B subunit delta (eIF-2B GDP-GTP exchange factor subunit delta).

MYST3_MOUSE
NC score	0.012093 (rank : 1759)	θ value	0.47712 (rank : 1264)
Query Neighborhood Hits	1959	Target Neighborhood Hits	688	Shared Neighborhood Hits	171
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

ATF2_MOUSE
NC score	0.012082 (rank : 1760)	θ value	5.27518 (rank : 1716)
Query Neighborhood Hits	1959	Target Neighborhood Hits	397	Shared Neighborhood Hits	103
SwissProt Accessions	P16951, Q64089, Q64090, Q64091	Gene names	Atf2
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (MXBP protein).

EVC_MOUSE
NC score	0.011976 (rank : 1761)	θ value	0.62314 (rank : 1289)
Query Neighborhood Hits	1959	Target Neighborhood Hits	80	Shared Neighborhood Hits	13
SwissProt Accessions	P57680	Gene names	Evc
Domain Architecture	No domain graphic available
Description	Ellis-van Creveld syndrome protein homolog.

HEMGN_MOUSE
NC score	0.011905 (rank : 1762)	θ value	8.99809 (rank : 1904)
Query Neighborhood Hits	1959	Target Neighborhood Hits	81	Shared Neighborhood Hits	42
SwissProt Accessions	Q9ERZ0, Q3TAE6, Q80YT2, Q8CF29	Gene names	Hemgn, Ndr
Domain Architecture	No domain graphic available
Description	Hemogen (Hemopoietic gene protein) (Negative differentiation regulator protein) (mNDR).

MEF2D_MOUSE
NC score	0.011798 (rank : 1763)	θ value	0.365318 (rank : 1222)
Query Neighborhood Hits	1959	Target Neighborhood Hits	146	Shared Neighborhood Hits	68
SwissProt Accessions	Q63943, Q63944	Gene names	Mef2d
Domain Architecture
Description	Myocyte-specific enhancer factor 2D.

CO1A1_MOUSE
NC score	0.011787 (rank : 1764)	θ value	5.27518 (rank : 1726)
Query Neighborhood Hits	1959	Target Neighborhood Hits	457	Shared Neighborhood Hits	142
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

MA1B1_HUMAN
NC score	0.011659 (rank : 1765)	θ value	0.813845 (rank : 1336)
Query Neighborhood Hits	1959	Target Neighborhood Hits	125	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UKM7, Q5VSG3, Q9BRS9, Q9Y5K7	Gene names	MAN1B1
Domain Architecture
Description	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (EC 3.2.1.113) (ER alpha-1,2-mannosidase) (Mannosidase alpha class 1B member 1) (Man9GlcNAc2-specific-processing alpha-mannosidase).

VGLL1_HUMAN
NC score	0.011606 (rank : 1766)	θ value	5.27518 (rank : 1790)
Query Neighborhood Hits	1959	Target Neighborhood Hits	12	Shared Neighborhood Hits	7
SwissProt Accessions	Q99990	Gene names	VGLL1, TDU
Domain Architecture	No domain graphic available
Description	Transcription cofactor vestigial-like protein 1 (Vgl-1) (Protein TONDU).

NUCKS_HUMAN
NC score	0.011577 (rank : 1767)	θ value	8.99809 (rank : 1925)
Query Neighborhood Hits	1959	Target Neighborhood Hits	143	Shared Neighborhood Hits	41
SwissProt Accessions	Q9H1E3, Q9H1D6, Q9H723	Gene names	NUCKS1, NUCKS
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (P1).

CA106_HUMAN
NC score	0.011574 (rank : 1768)	θ value	2.36792 (rank : 1524)
Query Neighborhood Hits	1959	Target Neighborhood Hits	124	Shared Neighborhood Hits	46
SwissProt Accessions	Q3KP66, Q9NV65, Q9NVI0	Gene names	C1orf106
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106.

PGCA_HUMAN
NC score	0.011468 (rank : 1769)	θ value	1.81305 (rank : 1504)
Query Neighborhood Hits	1959	Target Neighborhood Hits	821	Shared Neighborhood Hits	205
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

LAMA5_HUMAN
NC score	0.011467 (rank : 1770)	θ value	8.99809 (rank : 1920)
Query Neighborhood Hits	1959	Target Neighborhood Hits	976	Shared Neighborhood Hits	151
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

DBPA_HUMAN
NC score	0.011289 (rank : 1771)	θ value	1.06291 (rank : 1368)
Query Neighborhood Hits	1959	Target Neighborhood Hits	52	Shared Neighborhood Hits	20
SwissProt Accessions	P16989, Q14121, Q969N6	Gene names	CSDA, DBPA
Domain Architecture
Description	DNA-binding protein A (Cold shock domain-containing protein A) (Single-strand DNA-binding protein NF-GMB).

B4GN4_HUMAN
NC score	0.011277 (rank : 1772)	θ value	1.38821 (rank : 1425)
Query Neighborhood Hits	1959	Target Neighborhood Hits	131	Shared Neighborhood Hits	55
SwissProt Accessions	Q76KP1, Q96LV2	Gene names	B4GALNT4
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 1 (EC 2.4.1.244) (NGalNAc-T1) (Beta- 1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4).

E2F4_HUMAN
NC score	0.011131 (rank : 1773)	θ value	1.81305 (rank : 1480)
Query Neighborhood Hits	1959	Target Neighborhood Hits	188	Shared Neighborhood Hits	75
SwissProt Accessions	Q16254, Q12991, Q15328	Gene names	E2F4
Domain Architecture
Description	Transcription factor E2F4 (E2F-4).

H14_HUMAN
NC score	0.011108 (rank : 1774)	θ value	5.27518 (rank : 1741)
Query Neighborhood Hits	1959	Target Neighborhood Hits	87	Shared Neighborhood Hits	36
SwissProt Accessions	P10412	Gene names	HIST1H1E, H1F4
Domain Architecture
Description	Histone H1.4 (Histone H1b).

CITE4_MOUSE
NC score	0.011026 (rank : 1775)	θ value	6.88961 (rank : 1801)
Query Neighborhood Hits	1959	Target Neighborhood Hits	73	Shared Neighborhood Hits	35
SwissProt Accessions	Q9WUL8, Q66JX0, Q8R176, Q9CZV4	Gene names	Cited4, Mrg2
Domain Architecture	No domain graphic available
Description	Cbp/p300-interacting transactivator 4 (MSG1-related protein 2) (MRG- 2).

TRIPC_HUMAN
NC score	0.010976 (rank : 1776)	θ value	3.0926 (rank : 1626)
Query Neighborhood Hits	1959	Target Neighborhood Hits	319	Shared Neighborhood Hits	89
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

HD_HUMAN
NC score	0.010956 (rank : 1777)	θ value	8.99809 (rank : 1903)
Query Neighborhood Hits	1959	Target Neighborhood Hits	165	Shared Neighborhood Hits	65
SwissProt Accessions	P42858, Q9UQB7	Gene names	HD, IT15
Domain Architecture
Description	Huntingtin (Huntington disease protein) (HD protein).

HRSL5_HUMAN
NC score	0.010862 (rank : 1778)	θ value	0.365318 (rank : 1214)
Query Neighborhood Hits	1959	Target Neighborhood Hits	26	Shared Neighborhood Hits	11
SwissProt Accessions	Q96KN8	Gene names	HRASLS5, HRLP5
Domain Architecture
Description	HRAS-like suppressor 5 (H-rev107-like protein 5).

BSCL2_HUMAN
NC score	0.010816 (rank : 1779)	θ value	4.03905 (rank : 1638)
Query Neighborhood Hits	1959	Target Neighborhood Hits	148	Shared Neighborhood Hits	34
SwissProt Accessions	Q96G97, Q96SV1, Q9BSQ0	Gene names	BSCL2
Domain Architecture	No domain graphic available
Description	Seipin (Bernardinelli-Seip congenital lipodystrophy type 2 protein).

JADE2_HUMAN
NC score	0.010783 (rank : 1780)	θ value	0.0961366 (rank : 1107)
Query Neighborhood Hits	1959	Target Neighborhood Hits	199	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

ANKS6_MOUSE
NC score	0.010763 (rank : 1781)	θ value	5.27518 (rank : 1713)
Query Neighborhood Hits	1959	Target Neighborhood Hits	435	Shared Neighborhood Hits	81
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

LIPA3_MOUSE
NC score	0.010753 (rank : 1782)	θ value	5.27518 (rank : 1755)
Query Neighborhood Hits	1959	Target Neighborhood Hits	636	Shared Neighborhood Hits	76
SwissProt Accessions	P60469	Gene names	Ppfia3
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

RTN2_HUMAN
NC score	0.010734 (rank : 1783)	θ value	2.36792 (rank : 1561)
Query Neighborhood Hits	1959	Target Neighborhood Hits	59	Shared Neighborhood Hits	28
SwissProt Accessions	O75298, O60509, Q7RTM6, Q7RTN1, Q7RTN2	Gene names	RTN2, NSPL1
Domain Architecture
Description	Reticulon-2 (Neuroendocrine-specific protein-like 1) (NSP-like protein 1) (NSPLI).

PTCD1_HUMAN
NC score	0.010642 (rank : 1784)	θ value	1.06291 (rank : 1401)
Query Neighborhood Hits	1959	Target Neighborhood Hits	52	Shared Neighborhood Hits	24
SwissProt Accessions	O75127, Q66K60, Q9UDV2	Gene names	PTCD1, KIAA0632
Domain Architecture	No domain graphic available
Description	Pentatricopeptide repeat protein 1.

CLIC6_HUMAN
NC score	0.010354 (rank : 1785)	θ value	1.81305 (rank : 1474)
Query Neighborhood Hits	1959	Target Neighborhood Hits	289	Shared Neighborhood Hits	97
SwissProt Accessions	Q96NY7, Q8IX31	Gene names	CLIC6, CLIC1L
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel 6.

JHD3B_MOUSE
NC score	0.010318 (rank : 1786)	θ value	0.365318 (rank : 1217)
Query Neighborhood Hits	1959	Target Neighborhood Hits	152	Shared Neighborhood Hits	67
SwissProt Accessions	Q91VY5, Q3UR22, Q6ZQ30, Q99K42	Gene names	Jmjd2b, Jhdm3b
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

PA24B_MOUSE
NC score	0.010250 (rank : 1787)	θ value	2.36792 (rank : 1551)
Query Neighborhood Hits	1959	Target Neighborhood Hits	102	Shared Neighborhood Hits	17
SwissProt Accessions	Q4QQM1, Q80VV8, Q91W88	Gene names	Pla2g4b
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

XPC_HUMAN
NC score	0.010209 (rank : 1788)	θ value	2.36792 (rank : 1572)
Query Neighborhood Hits	1959	Target Neighborhood Hits	64	Shared Neighborhood Hits	23
SwissProt Accessions	Q01831, Q96AX0	Gene names	XPC, XPCC
Domain Architecture
Description	DNA-repair protein complementing XP-C cells (Xeroderma pigmentosum group C-complementing protein) (p125).

BRD3_HUMAN
NC score	0.010186 (rank : 1789)	θ value	8.99809 (rank : 1874)
Query Neighborhood Hits	1959	Target Neighborhood Hits	369	Shared Neighborhood Hits	92
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

SCG1_HUMAN
NC score	0.010176 (rank : 1790)	θ value	1.38821 (rank : 1456)
Query Neighborhood Hits	1959	Target Neighborhood Hits	156	Shared Neighborhood Hits	37
SwissProt Accessions	P05060, Q9BQV6, Q9UJA6	Gene names	CHGB, SCG1
Domain Architecture
Description	Secretogranin-1 precursor (Secretogranin I) (SgI) (Chromogranin B) (CgB) [Contains: GAWK peptide; CCB peptide].

SAM68_MOUSE
NC score	0.010170 (rank : 1791)	θ value	1.81305 (rank : 1512)
Query Neighborhood Hits	1959	Target Neighborhood Hits	65	Shared Neighborhood Hits	21
SwissProt Accessions	Q60749, Q3U8T3, Q60735, Q99M33	Gene names	Khdrbs1
Domain Architecture	No domain graphic available
Description	KH domain-containing, RNA-binding, signal transduction-associated protein 1 (p21 Ras GTPase-activating protein-associated p62) (GAP- associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p68).

FBX42_HUMAN
NC score	0.010122 (rank : 1792)	θ value	4.03905 (rank : 1656)
Query Neighborhood Hits	1959	Target Neighborhood Hits	121	Shared Neighborhood Hits	41
SwissProt Accessions	Q6P3S6, Q5TEU8, Q86XI0, Q8N3N4, Q8N5F8, Q9BRM0, Q9P2L4	Gene names	FBXO42, FBX42, KIAA1332
Domain Architecture	No domain graphic available
Description	F-box only protein 42.

DAB2_HUMAN
NC score	0.009967 (rank : 1793)	θ value	6.88961 (rank : 1809)
Query Neighborhood Hits	1959	Target Neighborhood Hits	197	Shared Neighborhood Hits	78
SwissProt Accessions	P98082, Q13598, Q9BTY0, Q9UK04	Gene names	DAB2, DOC2
Domain Architecture
Description	Disabled homolog 2 (Differentially expressed protein 2) (DOC-2).

LNP_MOUSE
NC score	0.009953 (rank : 1794)	θ value	5.27518 (rank : 1757)
Query Neighborhood Hits	1959	Target Neighborhood Hits	83	Shared Neighborhood Hits	41
SwissProt Accessions	Q7TQ95, Q69ZC5, Q6PAQ1, Q6PEN8	Gene names	Lnp, Kiaa1715, Uln
Domain Architecture	No domain graphic available
Description	Protein lunapark (Protein ulnaless).

TRI66_HUMAN
NC score	0.009946 (rank : 1795)	θ value	8.99809 (rank : 1947)
Query Neighborhood Hits	1959	Target Neighborhood Hits	479	Shared Neighborhood Hits	137
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

CO1A1_HUMAN
NC score	0.009940 (rank : 1796)	θ value	8.99809 (rank : 1885)
Query Neighborhood Hits	1959	Target Neighborhood Hits	475	Shared Neighborhood Hits	139
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

SAM68_HUMAN
NC score	0.009830 (rank : 1797)	θ value	1.06291 (rank : 1405)
Query Neighborhood Hits	1959	Target Neighborhood Hits	68	Shared Neighborhood Hits	27
SwissProt Accessions	Q07666, Q6PJX7, Q8NB97, Q99760	Gene names	KHDRBS1, SAM68
Domain Architecture	No domain graphic available
Description	KH domain-containing, RNA-binding, signal transduction-associated protein 1 (p21 Ras GTPase-activating protein-associated p62) (GAP- associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p68).

SAFB1_HUMAN
NC score	0.009552 (rank : 1798)	θ value	5.27518 (rank : 1779)
Query Neighborhood Hits	1959	Target Neighborhood Hits	493	Shared Neighborhood Hits	88
SwissProt Accessions	Q15424, O60406, Q59HH8	Gene names	SAFB, HAP, HET, SAFB1
Domain Architecture
Description	Scaffold attachment factor B (Scaffold attachment factor B1) (SAF-B) (HSP27 estrogen response element-TATA box-binding protein) (HSP27 ERE- TATA-binding protein).

MEF2A_HUMAN
NC score	0.009420 (rank : 1799)	θ value	0.365318 (rank : 1221)
Query Neighborhood Hits	1959	Target Neighborhood Hits	69	Shared Neighborhood Hits	25
SwissProt Accessions	Q02078, O43814, Q14223, Q14224, Q96D14	Gene names	MEF2A, MEF2
Domain Architecture
Description	Myocyte-specific enhancer factor 2A (Serum response factor-like protein 1).

DEN1A_MOUSE
NC score	0.009298 (rank : 1800)	θ value	4.03905 (rank : 1650)
Query Neighborhood Hits	1959	Target Neighborhood Hits	178	Shared Neighborhood Hits	78
SwissProt Accessions	Q8K382	Gene names	Dennd1a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

LIPA3_HUMAN
NC score	0.009266 (rank : 1801)	θ value	3.0926 (rank : 1601)
Query Neighborhood Hits	1959	Target Neighborhood Hits	828	Shared Neighborhood Hits	99
SwissProt Accessions	O75145, Q9H8B5, Q9UEW4	Gene names	PPFIA3, KIAA0654
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

NPHP4_MOUSE
NC score	0.009265 (rank : 1802)	θ value	1.81305 (rank : 1502)
Query Neighborhood Hits	1959	Target Neighborhood Hits	62	Shared Neighborhood Hits	28
SwissProt Accessions	P59240	Gene names	Nphp4
Domain Architecture	No domain graphic available
Description	Nephrocystin-4 (Nephroretinin).

WWC1_HUMAN
NC score	0.009249 (rank : 1803)	θ value	0.62314 (rank : 1311)
Query Neighborhood Hits	1959	Target Neighborhood Hits	290	Shared Neighborhood Hits	46
SwissProt Accessions	Q8IX03, O94946, Q6MZX4, Q6Y2F8, Q7Z4G8, Q8WVM4, Q9BT29	Gene names	WWC1, KIAA0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA) (HBeAg-binding protein 3).

BAI1_MOUSE
NC score	0.009182 (rank : 1804)	θ value	4.03905 (rank : 1636)
Query Neighborhood Hits	1959	Target Neighborhood Hits	340	Shared Neighborhood Hits	101
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

DUS8_HUMAN
NC score	0.009113 (rank : 1805)	θ value	0.47712 (rank : 1249)
Query Neighborhood Hits	1959	Target Neighborhood Hits	161	Shared Neighborhood Hits	60
SwissProt Accessions	Q13202	Gene names	DUSP8, VH5
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase hVH-5).

I20RA_MOUSE
NC score	0.009029 (rank : 1806)	θ value	4.03905 (rank : 1661)
Query Neighborhood Hits	1959	Target Neighborhood Hits	37	Shared Neighborhood Hits	13
SwissProt Accessions	Q6PHB0, Q8BW64	Gene names	Il20ra
Domain Architecture	No domain graphic available
Description	Interleukin-20 receptor alpha chain precursor (IL-20R-alpha) (IL- 20R1).

GAK7_HUMAN
NC score	0.009020 (rank : 1807)	θ value	8.99809 (rank : 1900)
Query Neighborhood Hits	1959	Target Neighborhood Hits	90	Shared Neighborhood Hits	48
SwissProt Accessions	Q96PI4, Q9QC08	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q23.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K18 Gag protein) (HERV-K110 Gag protein) (HERV-K(C1a) Gag protein) [Contains: Matrix protein].

DYN3_HUMAN
NC score	0.008964 (rank : 1808)	θ value	5.27518 (rank : 1734)
Query Neighborhood Hits	1959	Target Neighborhood Hits	158	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UQ16, O14982, O95555, Q5W129, Q9H0P3, Q9H548, Q9NQ68, Q9NQN6	Gene names	DNM3, KIAA0820
Domain Architecture
Description	Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin).

PYGO1_HUMAN
NC score	0.008866 (rank : 1809)	θ value	2.36792 (rank : 1559)
Query Neighborhood Hits	1959	Target Neighborhood Hits	90	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y3Y4	Gene names	PYGO1
Domain Architecture
Description	Pygopus homolog 1.

GNAS1_HUMAN
NC score	0.008805 (rank : 1810)	θ value	8.99809 (rank : 1902)
Query Neighborhood Hits	1959	Target Neighborhood Hits	278	Shared Neighborhood Hits	100
SwissProt Accessions	Q5JWF2, O75684, O75685, Q5JW67, Q5JWF1, Q9NY42	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

RBNS5_HUMAN
NC score	0.008741 (rank : 1811)	θ value	4.03905 (rank : 1684)
Query Neighborhood Hits	1959	Target Neighborhood Hits	242	Shared Neighborhood Hits	69
SwissProt Accessions	Q9H1K0, Q3KP30, Q59EY8, Q8NAQ1	Gene names	ZFYVE20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20) (110 kDa protein).

CAC1A_HUMAN
NC score	0.008707 (rank : 1812)	θ value	4.03905 (rank : 1640)
Query Neighborhood Hits	1959	Target Neighborhood Hits	387	Shared Neighborhood Hits	128
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

SEM4D_MOUSE
NC score	0.008705 (rank : 1813)	θ value	3.0926 (rank : 1613)
Query Neighborhood Hits	1959	Target Neighborhood Hits	143	Shared Neighborhood Hits	55
SwissProt Accessions	O09126	Gene names	Sema4d, Semacl2, Semaj
Domain Architecture
Description	Semaphorin-4D precursor (Semaphorin J) (Sema J) (Semaphorin C-like 2) (M-Sema G).

SNIP1_MOUSE
NC score	0.008544 (rank : 1814)	θ value	8.99809 (rank : 1939)
Query Neighborhood Hits	1959	Target Neighborhood Hits	113	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BIZ6, Q3V106, Q8BIZ4	Gene names	Snip1
Domain Architecture
Description	Smad nuclear-interacting protein 1.

DBPA_MOUSE
NC score	0.008406 (rank : 1815)	θ value	3.0926 (rank : 1583)
Query Neighborhood Hits	1959	Target Neighborhood Hits	64	Shared Neighborhood Hits	31
SwissProt Accessions	Q9JKB3, Q80WG4, Q9EQF7, Q9EQF8	Gene names	Csda, Msy4, Ybx3
Domain Architecture	No domain graphic available
Description	DNA-binding protein A (Cold shock domain-containing protein A) (Y-box protein 3).

P73L_HUMAN
NC score	0.008376 (rank : 1816)	θ value	1.38821 (rank : 1451)
Query Neighborhood Hits	1959	Target Neighborhood Hits	102	Shared Neighborhood Hits	43
SwissProt Accessions	Q9H3D4, O75080, O75195, O75922, O76078, Q6VEG2, Q6VEG3, Q6VEG4, Q6VFJ1, Q6VFJ2, Q6VFJ3, Q6VH20, Q7LDI3, Q7LDI4, Q7LDI5, Q96KR0, Q9H3D2, Q9H3D3, Q9H3P8, Q9NPH7, Q9P1B4, Q9P1B5, Q9P1B6, Q9P1B7, Q9UBV9, Q9UE10, Q9UP26, Q9UP27, Q9UP28, Q9UP74	Gene names	TP73L, KET, P63, P73H, P73L
Domain Architecture	No domain graphic available
Description	Tumor protein p73-like (p73L) (p63) (Tumor protein 63) (TP63) (p51) (p40) (Keratinocyte transcription factor KET) (Chronic ulcerative stomatitis protein) (CUSP).

MELPH_HUMAN
NC score	0.008348 (rank : 1817)	θ value	5.27518 (rank : 1761)
Query Neighborhood Hits	1959	Target Neighborhood Hits	145	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BV36, Q9HA71	Gene names	MLPH, SLAC2A
Domain Architecture	No domain graphic available
Description	Melanophilin (Exophilin-3) (Synaptotagmin-like protein 2a) (Slp homolog lacking C2 domains a).

CNTP1_MOUSE
NC score	0.008303 (rank : 1818)	θ value	0.813845 (rank : 1318)
Query Neighborhood Hits	1959	Target Neighborhood Hits	183	Shared Neighborhood Hits	32
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

JPH3_MOUSE
NC score	0.008263 (rank : 1819)	θ value	5.27518 (rank : 1750)
Query Neighborhood Hits	1959	Target Neighborhood Hits	80	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ET77, Q9EQZ2	Gene names	Jph3, Jp3
Domain Architecture
Description	Junctophilin-3 (Junctophilin type 3) (JP-3).

SIX5_MOUSE
NC score	0.008254 (rank : 1820)	θ value	0.21417 (rank : 1170)
Query Neighborhood Hits	1959	Target Neighborhood Hits	354	Shared Neighborhood Hits	82
SwissProt Accessions	P70178	Gene names	Six5, Dmahp
Domain Architecture
Description	Homeobox protein SIX5 (DM locus-associated homeodomain protein homolog).

COGA1_HUMAN
NC score	0.008099 (rank : 1821)	θ value	1.81305 (rank : 1475)
Query Neighborhood Hits	1959	Target Neighborhood Hits	345	Shared Neighborhood Hits	112
SwissProt Accessions	Q07092	Gene names	COL16A1
Domain Architecture
Description	Collagen alpha-1(XVI) chain precursor.

CALX_HUMAN
NC score	0.008076 (rank : 1822)	θ value	2.36792 (rank : 1525)
Query Neighborhood Hits	1959	Target Neighborhood Hits	96	Shared Neighborhood Hits	29
SwissProt Accessions	P27824	Gene names	CANX
Domain Architecture
Description	Calnexin precursor (Major histocompatibility complex class I antigen- binding protein p88) (p90) (IP90).

SIA7A_HUMAN
NC score	0.008065 (rank : 1823)	θ value	8.99809 (rank : 1938)
Query Neighborhood Hits	1959	Target Neighborhood Hits	177	Shared Neighborhood Hits	69
SwissProt Accessions	Q9NSC7, Q6UW90, Q9NSC6	Gene names	ST6GALNAC1, SIAT7A
Domain Architecture
Description	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (EC 2.4.99.3) (GalNAc alpha-2,6-sialyltransferase I) (ST6GalNAc I) (Sialyltransferase 7A).

ARHG1_MOUSE
NC score	0.008018 (rank : 1824)	θ value	0.813845 (rank : 1313)
Query Neighborhood Hits	1959	Target Neighborhood Hits	266	Shared Neighborhood Hits	91
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

GCFC_HUMAN
NC score	0.007899 (rank : 1825)	θ value	1.81305 (rank : 1487)
Query Neighborhood Hits	1959	Target Neighborhood Hits	86	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y5B6, Q9NYQ0	Gene names	GCFC, C21orf66
Domain Architecture	No domain graphic available
Description	GC-rich sequence DNA-binding factor homolog.

CD5R2_MOUSE
NC score	0.007889 (rank : 1826)	θ value	8.99809 (rank : 1880)
Query Neighborhood Hits	1959	Target Neighborhood Hits	57	Shared Neighborhood Hits	34
SwissProt Accessions	O35926, O35277	Gene names	Cdk5r2, Nck5ai
Domain Architecture
Description	Cyclin-dependent kinase 5 activator 2 precursor (CDK5 activator 2) (Cyclin-dependent kinase 5 regulatory subunit 2) (P39) (P39I).

PAX1_HUMAN
NC score	0.007838 (rank : 1827)	θ value	0.0431538 (rank : 1062)
Query Neighborhood Hits	1959	Target Neighborhood Hits	72	Shared Neighborhood Hits	24
SwissProt Accessions	P15863, Q642X9, Q6NTC0, Q9Y558	Gene names	PAX1, HUP48
Domain Architecture
Description	Paired box protein Pax-1 (HUP48).

SCMH1_MOUSE
NC score	0.007823 (rank : 1828)	θ value	2.36792 (rank : 1562)
Query Neighborhood Hits	1959	Target Neighborhood Hits	87	Shared Neighborhood Hits	36
SwissProt Accessions	Q8K214, Q9JME0	Gene names	Scmh1
Domain Architecture	No domain graphic available
Description	Polycomb protein SCMH1 (Sex comb on midleg homolog 1).

SAM14_HUMAN
NC score	0.007701 (rank : 1829)	θ value	5.27518 (rank : 1780)
Query Neighborhood Hits	1959	Target Neighborhood Hits	81	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IZD0, Q8N2X0	Gene names	SAMD14
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 14.

DIP2A_HUMAN
NC score	0.007651 (rank : 1830)	θ value	1.81305 (rank : 1478)
Query Neighborhood Hits	1959	Target Neighborhood Hits	48	Shared Neighborhood Hits	18
SwissProt Accessions	Q14689, Q8IVA3, Q8N4S2, Q8TD89, Q96ML9	Gene names	DIP2A, C21orf106, DIP2, KIAA0184
Domain Architecture
Description	Disco-interacting protein 2 homolog A.

SOX30_MOUSE
NC score	0.007621 (rank : 1831)	θ value	5.27518 (rank : 1783)
Query Neighborhood Hits	1959	Target Neighborhood Hits	374	Shared Neighborhood Hits	137
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

ARHG3_HUMAN
NC score	0.007571 (rank : 1832)	θ value	1.81305 (rank : 1466)
Query Neighborhood Hits	1959	Target Neighborhood Hits	82	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NR81, Q6NUN3, Q7Z4U2, Q7Z5T2, Q9H7T4	Gene names	ARHGEF3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3 (Exchange factor found in platelets and leukemic and neuronal tissues) (XPLN).

SAM14_MOUSE
NC score	0.007518 (rank : 1833)	θ value	8.99809 (rank : 1935)
Query Neighborhood Hits	1959	Target Neighborhood Hits	91	Shared Neighborhood Hits	33
SwissProt Accessions	Q8K070, Q5SWB7, Q8BHE2, Q8C8N5	Gene names	Samd14
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 14.

CTGE6_HUMAN
NC score	0.007455 (rank : 1834)	θ value	1.06291 (rank : 1367)
Query Neighborhood Hits	1959	Target Neighborhood Hits	650	Shared Neighborhood Hits	75
SwissProt Accessions	Q86UF2	Gene names	CTAGE6
Domain Architecture	No domain graphic available
Description	Protein cTAGE-6 (cTAGE family member 6).

ATS14_HUMAN
NC score	0.007373 (rank : 1835)	θ value	1.38821 (rank : 1424)
Query Neighborhood Hits	1959	Target Neighborhood Hits	382	Shared Neighborhood Hits	129
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

MUCB_HUMAN
NC score	0.007331 (rank : 1836)	θ value	4.03905 (rank : 1671)
Query Neighborhood Hits	1959	Target Neighborhood Hits	233	Shared Neighborhood Hits	33
SwissProt Accessions	P04220	Gene names
Domain Architecture	No domain graphic available
Description	Ig mu heavy chain disease protein (BOT).

TBC10_MOUSE
NC score	0.007282 (rank : 1837)	θ value	2.36792 (rank : 1570)
Query Neighborhood Hits	1959	Target Neighborhood Hits	94	Shared Neighborhood Hits	36
SwissProt Accessions	P58802	Gene names	Tbc1d10a, Epi64, Tbc1d10
Domain Architecture
Description	TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa) (EPI64 protein).

PP16A_HUMAN
NC score	0.007269 (rank : 1838)	θ value	6.88961 (rank : 1843)
Query Neighborhood Hits	1959	Target Neighborhood Hits	340	Shared Neighborhood Hits	53
SwissProt Accessions	Q96I34	Gene names	PPP1R16A, MYPT3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase- targeting subunit 3).

HD_MOUSE
NC score	0.007174 (rank : 1839)	θ value	5.27518 (rank : 1745)
Query Neighborhood Hits	1959	Target Neighborhood Hits	116	Shared Neighborhood Hits	43
SwissProt Accessions	P42859	Gene names	Hd, Hdh
Domain Architecture
Description	Huntingtin (Huntington disease protein homolog) (HD protein).

MUC_HUMAN
NC score	0.007063 (rank : 1840)	θ value	4.03905 (rank : 1672)
Query Neighborhood Hits	1959	Target Neighborhood Hits	231	Shared Neighborhood Hits	31
SwissProt Accessions	P01871	Gene names	IGHM
Domain Architecture
Description	Ig mu chain C region.

ZO3_MOUSE
NC score	0.007019 (rank : 1841)	θ value	4.03905 (rank : 1706)
Query Neighborhood Hits	1959	Target Neighborhood Hits	224	Shared Neighborhood Hits	47
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

RECQ4_HUMAN
NC score	0.006933 (rank : 1842)	θ value	0.365318 (rank : 1232)
Query Neighborhood Hits	1959	Target Neighborhood Hits	177	Shared Neighborhood Hits	51
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

DVL3_HUMAN
NC score	0.006914 (rank : 1843)	θ value	0.0736092 (rank : 1089)
Query Neighborhood Hits	1959	Target Neighborhood Hits	194	Shared Neighborhood Hits	38
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

ANKR6_HUMAN
NC score	0.006907 (rank : 1844)	θ value	8.99809 (rank : 1865)
Query Neighborhood Hits	1959	Target Neighborhood Hits	439	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

C2TA_HUMAN
NC score	0.006877 (rank : 1845)	θ value	8.99809 (rank : 1877)
Query Neighborhood Hits	1959	Target Neighborhood Hits	190	Shared Neighborhood Hits	74
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

CLGN_MOUSE
NC score	0.006858 (rank : 1846)	θ value	6.88961 (rank : 1802)
Query Neighborhood Hits	1959	Target Neighborhood Hits	142	Shared Neighborhood Hits	33
SwissProt Accessions	P52194, Q9D2K5	Gene names	Clgn, Meg1
Domain Architecture
Description	Calmegin precursor (MEG 1 antigen) (Calnexin-T) (A2/6).

PO6F2_MOUSE
NC score	0.006849 (rank : 1847)	θ value	4.03905 (rank : 1682)
Query Neighborhood Hits	1959	Target Neighborhood Hits	639	Shared Neighborhood Hits	175
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

CP053_MOUSE
NC score	0.006806 (rank : 1848)	θ value	8.99809 (rank : 1888)
Query Neighborhood Hits	1959	Target Neighborhood Hits	38	Shared Neighborhood Hits	14
SwissProt Accessions	Q99L02	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf53 homolog.

ANR47_HUMAN
NC score	0.006801 (rank : 1849)	θ value	2.36792 (rank : 1521)
Query Neighborhood Hits	1959	Target Neighborhood Hits	369	Shared Neighborhood Hits	66
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

RNPS1_HUMAN
NC score	0.006738 (rank : 1850)	θ value	4.03905 (rank : 1688)
Query Neighborhood Hits	1959	Target Neighborhood Hits	285	Shared Neighborhood Hits	56
SwissProt Accessions	Q15287, O75308, Q8WY42, Q9NYG3	Gene names	RNPS1, LDC2
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2).

RNPS1_MOUSE
NC score	0.006738 (rank : 1851)	θ value	4.03905 (rank : 1689)
Query Neighborhood Hits	1959	Target Neighborhood Hits	285	Shared Neighborhood Hits	56
SwissProt Accessions	Q99M28, Q3TMJ1, Q922H8	Gene names	Rnps1
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1.

DAB2P_HUMAN
NC score	0.006492 (rank : 1852)	θ value	6.88961 (rank : 1807)
Query Neighborhood Hits	1959	Target Neighborhood Hits	303	Shared Neighborhood Hits	64
SwissProt Accessions	Q5VWQ8, Q8TDL2, Q96SE1, Q9C0C0	Gene names	DAB2IP, AF9Q34, AIP1, KIAA1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein) (DAB2 interaction protein) (ASK-interacting protein 1).

BAI2_MOUSE
NC score	0.006476 (rank : 1853)	θ value	5.27518 (rank : 1719)
Query Neighborhood Hits	1959	Target Neighborhood Hits	323	Shared Neighborhood Hits	66
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

DVL3_MOUSE
NC score	0.006469 (rank : 1854)	θ value	0.365318 (rank : 1207)
Query Neighborhood Hits	1959	Target Neighborhood Hits	198	Shared Neighborhood Hits	46
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

TSKS_HUMAN
NC score	0.006446 (rank : 1855)	θ value	8.99809 (rank : 1949)
Query Neighborhood Hits	1959	Target Neighborhood Hits	220	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UJT2, Q8WXJ0	Gene names	STK22S1, TSKS, TSKS1
Domain Architecture	No domain graphic available
Description	Testis-specific serine kinase substrate (Testis-specific kinase substrate) (STK22 substrate 1).

IP3KB_HUMAN
NC score	0.006426 (rank : 1856)	θ value	8.99809 (rank : 1911)
Query Neighborhood Hits	1959	Target Neighborhood Hits	124	Shared Neighborhood Hits	40
SwissProt Accessions	P27987, Q5VWL9, Q5VWM0, Q96BZ2, Q96JS1, Q9UH47	Gene names	ITPKB
Domain Architecture
Description	Inositol-trisphosphate 3-kinase B (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase B) (IP3K B) (IP3 3-kinase B) (IP3K-B).

BAI2_HUMAN
NC score	0.006421 (rank : 1857)	θ value	4.03905 (rank : 1637)
Query Neighborhood Hits	1959	Target Neighborhood Hits	332	Shared Neighborhood Hits	76
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

TM16H_MOUSE
NC score	0.006374 (rank : 1858)	θ value	5.27518 (rank : 1788)
Query Neighborhood Hits	1959	Target Neighborhood Hits	65	Shared Neighborhood Hits	18
SwissProt Accessions	Q6PB70, Q69ZE4	Gene names	Tmem16h, Kiaa1623
Domain Architecture	No domain graphic available
Description	Transmembrane protein 16H.

CO5A1_MOUSE
NC score	0.006367 (rank : 1859)	θ value	6.88961 (rank : 1804)
Query Neighborhood Hits	1959	Target Neighborhood Hits	419	Shared Neighborhood Hits	137
SwissProt Accessions	O88207	Gene names	Col5a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(V) chain precursor.

TBC10_HUMAN
NC score	0.006356 (rank : 1860)	θ value	2.36792 (rank : 1569)
Query Neighborhood Hits	1959	Target Neighborhood Hits	64	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BXI6, O76053, Q543A2	Gene names	TBC1D10A, EPI64, TBC1D10
Domain Architecture
Description	TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa) (EPI64 protein).

QSCN6_HUMAN
NC score	0.006319 (rank : 1861)	θ value	1.06291 (rank : 1402)
Query Neighborhood Hits	1959	Target Neighborhood Hits	98	Shared Neighborhood Hits	30
SwissProt Accessions	O00391, Q59G29, Q5T2X0, Q8TDL6, Q8WVP4	Gene names	QSCN6, QSOX1
Domain Architecture	No domain graphic available
Description	Sulfhydryl oxidase 1 precursor (EC 1.8.3.2) (Quiescin Q6) (hQSOX).

PERQ1_HUMAN
NC score	0.006196 (rank : 1862)	θ value	4.03905 (rank : 1677)
Query Neighborhood Hits	1959	Target Neighborhood Hits	28	Shared Neighborhood Hits	8
SwissProt Accessions	O75420	Gene names	PERQ1
Domain Architecture
Description	PERQ amino acid rich with GYF domain protein 1.

PO6F2_HUMAN
NC score	0.006179 (rank : 1863)	θ value	5.27518 (rank : 1773)
Query Neighborhood Hits	1959	Target Neighborhood Hits	618	Shared Neighborhood Hits	159
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

TECT3_MOUSE
NC score	0.006175 (rank : 1864)	θ value	1.38821 (rank : 1460)
Query Neighborhood Hits	1959	Target Neighborhood Hits	33	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R2Q6, Q8CDF3, Q9CRC5	Gene names	Tect3
Domain Architecture	No domain graphic available
Description	Tectonic-3 precursor.

ATF6A_HUMAN
NC score	0.006150 (rank : 1865)	θ value	8.99809 (rank : 1866)
Query Neighborhood Hits	1959	Target Neighborhood Hits	174	Shared Neighborhood Hits	37
SwissProt Accessions	P18850, O15139, Q5VW62, Q6IPB5, Q9UEC9	Gene names	ATF6
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 alpha (Activating transcription factor 6 alpha) (ATF6-alpha).

COIA1_MOUSE
NC score	0.006140 (rank : 1866)	θ value	8.99809 (rank : 1887)
Query Neighborhood Hits	1959	Target Neighborhood Hits	481	Shared Neighborhood Hits	154
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

CO5A1_HUMAN
NC score	0.006109 (rank : 1867)	θ value	4.03905 (rank : 1646)
Query Neighborhood Hits	1959	Target Neighborhood Hits	434	Shared Neighborhood Hits	136
SwissProt Accessions	P20908, Q15094, Q5SUX4	Gene names	COL5A1
Domain Architecture
Description	Collagen alpha-1(V) chain precursor.

DNM3B_MOUSE
NC score	0.006046 (rank : 1868)	θ value	0.365318 (rank : 1206)
Query Neighborhood Hits	1959	Target Neighborhood Hits	61	Shared Neighborhood Hits	12
SwissProt Accessions	O88509, O88510, O88511	Gene names	Dnmt3b
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3B (EC 2.1.1.37) (Dnmt3b) (DNA methyltransferase MmuIIIB) (DNA MTase MmuIIIB) (M.MmuIIIB).

USBP1_HUMAN
NC score	0.006045 (rank : 1869)	θ value	1.06291 (rank : 1415)
Query Neighborhood Hits	1959	Target Neighborhood Hits	188	Shared Neighborhood Hits	32
SwissProt Accessions	Q8N6Y0, Q8NBX7, Q96KH3, Q9BYI8	Gene names	USHBP1, AIEBP, MCC2
Domain Architecture	No domain graphic available
Description	USH1C-binding protein 1 (Usher syndrome type-1C protein-binding protein 1) (MCC-2) (AIE-75 binding protein).

FBX42_MOUSE
NC score	0.006004 (rank : 1870)	θ value	2.36792 (rank : 1533)
Query Neighborhood Hits	1959	Target Neighborhood Hits	84	Shared Neighborhood Hits	25
SwissProt Accessions	Q6PDJ6, Q8CE76, Q99KY2	Gene names	Fbxo42
Domain Architecture	No domain graphic available
Description	F-box only protein 42.

DAZP2_MOUSE
NC score	0.005952 (rank : 1871)	θ value	6.88961 (rank : 1811)
Query Neighborhood Hits	1959	Target Neighborhood Hits	35	Shared Neighborhood Hits	15
SwissProt Accessions	Q9DCP9, O88675, Q3UVI4	Gene names	Dazap2, Prtb
Domain Architecture	No domain graphic available
Description	DAZ-associated protein 2 (Deleted in azoospermia-associated protein 2) (Proline-rich protein expressed in brain).

JHD3B_HUMAN
NC score	0.005908 (rank : 1872)	θ value	0.62314 (rank : 1295)
Query Neighborhood Hits	1959	Target Neighborhood Hits	128	Shared Neighborhood Hits	43
SwissProt Accessions	O94953, O75274, Q6P3R5, Q9P1V1, Q9UF40	Gene names	JMJD2B, JHDM3B, KIAA0876
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

N4BP3_HUMAN
NC score	0.005882 (rank : 1873)	θ value	6.88961 (rank : 1834)
Query Neighborhood Hits	1959	Target Neighborhood Hits	156	Shared Neighborhood Hits	21
SwissProt Accessions	O15049, Q7Z6I3	Gene names	N4BP3, KIAA0341
Domain Architecture
Description	NEDD4-binding protein 3 (N4BP3).

PPAC3_MOUSE
NC score	0.005798 (rank : 1874)	θ value	0.813845 (rank : 1341)
Query Neighborhood Hits	1959	Target Neighborhood Hits	22	Shared Neighborhood Hits	6
SwissProt Accessions	Q91WB2	Gene names	Ppapdc3
Domain Architecture	No domain graphic available
Description	Probable lipid phosphate phosphatase PPAPDC3 (EC 3.1.3.-) (Phosphatidic acid phosphatase type 2 domain-containing protein 3).

CBLB_MOUSE
NC score	0.005777 (rank : 1875)	θ value	8.99809 (rank : 1879)
Query Neighborhood Hits	1959	Target Neighborhood Hits	277	Shared Neighborhood Hits	57
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

PDLI7_MOUSE
NC score	0.005777 (rank : 1876)	θ value	0.163984 (rank : 1140)
Query Neighborhood Hits	1959	Target Neighborhood Hits	279	Shared Neighborhood Hits	47
SwissProt Accessions	Q3TJD7, Q80ZY6, Q810S3, Q8C1S4, Q9CRA1	Gene names	Pdlim7, Enigma
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

FOSL2_MOUSE
NC score	0.005617 (rank : 1877)	θ value	0.813845 (rank : 1326)
Query Neighborhood Hits	1959	Target Neighborhood Hits	151	Shared Neighborhood Hits	22
SwissProt Accessions	P47930	Gene names	Fosl2, Fra-2, Fra2
Domain Architecture	No domain graphic available
Description	Fos-related antigen 2.

DAB2P_MOUSE
NC score	0.005611 (rank : 1878)	θ value	6.88961 (rank : 1808)
Query Neighborhood Hits	1959	Target Neighborhood Hits	284	Shared Neighborhood Hits	54
SwissProt Accessions	Q3UHC7, Q3TPD5, Q3UH44, Q6JTV1, Q80T97	Gene names	Dab2ip, Kiaa1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein).

DAZP2_HUMAN
NC score	0.005426 (rank : 1879)	θ value	6.88961 (rank : 1810)
Query Neighborhood Hits	1959	Target Neighborhood Hits	33	Shared Neighborhood Hits	13
SwissProt Accessions	Q15038	Gene names	DAZAP2, KIAA0058
Domain Architecture	No domain graphic available
Description	DAZ-associated protein 2 (Deleted in azoospermia-associated protein 2).

CAC1B_MOUSE
NC score	0.005356 (rank : 1880)	θ value	8.99809 (rank : 1878)
Query Neighborhood Hits	1959	Target Neighborhood Hits	351	Shared Neighborhood Hits	114
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

DIP2A_MOUSE
NC score	0.005308 (rank : 1881)	θ value	3.0926 (rank : 1585)
Query Neighborhood Hits	1959	Target Neighborhood Hits	32	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BWT5, Q8CHI0	Gene names	Dip2a, Dip2, Kiaa0184
Domain Architecture
Description	Disco-interacting protein 2 homolog A.

CAC1H_MOUSE
NC score	0.005199 (rank : 1882)	θ value	0.21417 (rank : 1151)
Query Neighborhood Hits	1959	Target Neighborhood Hits	230	Shared Neighborhood Hits	83
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

CEBPD_HUMAN
NC score	0.005181 (rank : 1883)	θ value	8.99809 (rank : 1881)
Query Neighborhood Hits	1959	Target Neighborhood Hits	135	Shared Neighborhood Hits	39
SwissProt Accessions	P49716, Q14937	Gene names	CEBPD
Domain Architecture
Description	CCAAT/enhancer-binding protein delta (C/EBP delta) (Nuclear factor NF- IL6-beta) (NF-IL6-beta).

MEN1_HUMAN
NC score	0.005124 (rank : 1884)	θ value	5.27518 (rank : 1762)
Query Neighborhood Hits	1959	Target Neighborhood Hits	21	Shared Neighborhood Hits	12
SwissProt Accessions	O00255, O00632, Q9BUK2	Gene names	MEN1, SCG2
Domain Architecture
Description	Menin.

IQEC3_HUMAN
NC score	0.004918 (rank : 1885)	θ value	0.813845 (rank : 1332)
Query Neighborhood Hits	1959	Target Neighborhood Hits	125	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UPP2, Q8TB43	Gene names	IQSEC3, KIAA1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

NFIC_MOUSE
NC score	0.004823 (rank : 1886)	θ value	1.06291 (rank : 1394)
Query Neighborhood Hits	1959	Target Neighborhood Hits	66	Shared Neighborhood Hits	26
SwissProt Accessions	P70255, O09072, P70256, Q3U2I9, Q99MA3, Q99MA4, Q99MA5, Q99MA6, Q99MA7, Q99MA8, Q9R1G3	Gene names	Nfic
Domain Architecture
Description	Nuclear factor 1 C-type (Nuclear factor 1/C) (NF1-C) (NFI-C) (NF-I/C) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

TF3B_HUMAN
NC score	0.004785 (rank : 1887)	θ value	5.27518 (rank : 1787)
Query Neighborhood Hits	1959	Target Neighborhood Hits	60	Shared Neighborhood Hits	20
SwissProt Accessions	Q92994, Q13223, Q5PR24, Q6IQ02, Q9HCW6, Q9HCW7, Q9HCW8	Gene names	BRF1, BRF
Domain Architecture
Description	Transcription factor IIIB 90 kDa subunit (TFIIIB90) (hTFIIIB90) (B- related factor 1) (BRF-1) (hBRF) (TATA box-binding protein-associated factor, RNA polymerase III, subunit 2) (TAF3B2).

ASB2_MOUSE
NC score	0.004740 (rank : 1888)	θ value	6.88961 (rank : 1795)
Query Neighborhood Hits	1959	Target Neighborhood Hits	321	Shared Neighborhood Hits	37
SwissProt Accessions	Q8K0L0, Q9CTH4, Q9WV73	Gene names	Asb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

HDAC7_HUMAN
NC score	0.004717 (rank : 1889)	θ value	0.62314 (rank : 1292)
Query Neighborhood Hits	1959	Target Neighborhood Hits	64	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WUI4, Q7Z5I1, Q96K01, Q9BR73, Q9H7L0, Q9NW41, Q9NWA9, Q9NYK9, Q9UFU7	Gene names	HDAC7A, HDAC7
Domain Architecture
Description	Histone deacetylase 7a (HD7a).

K1849_MOUSE
NC score	0.004627 (rank : 1890)	θ value	5.27518 (rank : 1751)
Query Neighborhood Hits	1959	Target Neighborhood Hits	335	Shared Neighborhood Hits	82
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

SGOL2_MOUSE
NC score	0.004416 (rank : 1891)	θ value	4.03905 (rank : 1691)
Query Neighborhood Hits	1959	Target Neighborhood Hits	112	Shared Neighborhood Hits	15
SwissProt Accessions	Q7TSY8, Q811I4, Q8C9C4, Q8CGJ4, Q9CS55	Gene names	Sgol2
Domain Architecture	No domain graphic available
Description	Shugoshin-like 2.

HDAC7_MOUSE
NC score	0.004361 (rank : 1892)	θ value	1.38821 (rank : 1437)
Query Neighborhood Hits	1959	Target Neighborhood Hits	85	Shared Neighborhood Hits	22
SwissProt Accessions	Q8C2B3, Q8C2C9, Q8C8X4, Q8CB80, Q8CDA3, Q9JL72	Gene names	Hdac7a, Hdac7
Domain Architecture
Description	Histone deacetylase 7a (HD7a).

CENG1_HUMAN
NC score	0.004081 (rank : 1893)	θ value	0.0252991 (rank : 1026)
Query Neighborhood Hits	1959	Target Neighborhood Hits	544	Shared Neighborhood Hits	103
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

ETV5_MOUSE
NC score	0.004051 (rank : 1894)	θ value	4.03905 (rank : 1655)
Query Neighborhood Hits	1959	Target Neighborhood Hits	328	Shared Neighborhood Hits	120
SwissProt Accessions	Q9CXC9, Q3TG49, Q8C0F3, Q9JHB1	Gene names	Etv5
Domain Architecture	No domain graphic available
Description	ETS translocation variant 5.

NDC1_MOUSE
NC score	0.004018 (rank : 1895)	θ value	5.27518 (rank : 1767)
Query Neighborhood Hits	1959	Target Neighborhood Hits	45	Shared Neighborhood Hits	17
SwissProt Accessions	Q8VCB1	Gene names	Tmem48, Ndc1
Domain Architecture	No domain graphic available
Description	Nucleoporin NDC1 (Transmembrane protein 48).

IER2_HUMAN
NC score	0.003949 (rank : 1896)	θ value	8.99809 (rank : 1907)
Query Neighborhood Hits	1959	Target Neighborhood Hits	29	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BTL4, Q03827, Q2TAZ2	Gene names	IER2, ETR101
Domain Architecture	No domain graphic available
Description	Immediate early response gene 2 protein (Protein ETR101).

SIX5_HUMAN
NC score	0.003917 (rank : 1897)	θ value	3.0926 (rank : 1617)
Query Neighborhood Hits	1959	Target Neighborhood Hits	386	Shared Neighborhood Hits	80
SwissProt Accessions	Q8N196	Gene names	SIX5, DMAHP
Domain Architecture	No domain graphic available
Description	Homeobox protein SIX5 (DM locus-associated homeodomain protein).

CAC1B_HUMAN
NC score	0.003900 (rank : 1898)	θ value	0.0736092 (rank : 1088)
Query Neighborhood Hits	1959	Target Neighborhood Hits	257	Shared Neighborhood Hits	73
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

ZCC2_HUMAN
NC score	0.003851 (rank : 1899)	θ value	4.03905 (rank : 1703)
Query Neighborhood Hits	1959	Target Neighborhood Hits	47	Shared Neighborhood Hits	14
SwissProt Accessions	Q7Z2W4, Q8IW57, Q8TAJ3, Q96N79, Q9H8R9, Q9P0Y7	Gene names	ZC3HAV1, ZC3HDC2
Domain Architecture
Description	Zinc finger CCCH type antiviral protein 1 (Zinc finger CCCH domain- containing protein 2).

GGA3_HUMAN
NC score	0.003849 (rank : 1900)	θ value	4.03905 (rank : 1658)
Query Neighborhood Hits	1959	Target Neighborhood Hits	127	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NZ52, Q15017, Q6IS16, Q9UJY3	Gene names	GGA3, KIAA0154
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

CLGN_HUMAN
NC score	0.003828 (rank : 1901)	θ value	2.36792 (rank : 1528)
Query Neighborhood Hits	1959	Target Neighborhood Hits	111	Shared Neighborhood Hits	20
SwissProt Accessions	O14967	Gene names	CLGN
Domain Architecture
Description	Calmegin precursor.

SOX5_HUMAN
NC score	0.003791 (rank : 1902)	θ value	3.0926 (rank : 1621)
Query Neighborhood Hits	1959	Target Neighborhood Hits	219	Shared Neighborhood Hits	40
SwissProt Accessions	P35711, Q86UK8, Q8J017, Q8J018, Q8J019, Q8J020, Q8N1D9, Q8N7E0, Q8TEA4	Gene names	SOX5
Domain Architecture
Description	Transcription factor SOX-5.

DDX51_HUMAN
NC score	0.003737 (rank : 1903)	θ value	0.47712 (rank : 1248)
Query Neighborhood Hits	1959	Target Neighborhood Hits	332	Shared Neighborhood Hits	94
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

K1024_MOUSE
NC score	0.003692 (rank : 1904)	θ value	4.03905 (rank : 1665)
Query Neighborhood Hits	1959	Target Neighborhood Hits	57	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K3V7, Q69ZS9	Gene names	Kiaa1024
Domain Architecture
Description	UPF0258 protein KIAA1024 (Protein DD1).

TM119_MOUSE
NC score	0.003664 (rank : 1905)	θ value	6.88961 (rank : 1852)
Query Neighborhood Hits	1959	Target Neighborhood Hits	30	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R138, Q8BP14	Gene names	Tmem119
Domain Architecture	No domain graphic available
Description	Transmembrane protein 119 precursor.

NPAS1_HUMAN
NC score	0.003484 (rank : 1906)	θ value	0.163984 (rank : 1138)
Query Neighborhood Hits	1959	Target Neighborhood Hits	77	Shared Neighborhood Hits	21
SwissProt Accessions	Q99742, Q99632, Q9BY83	Gene names	NPAS1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1) (Member of PAS protein 5) (MOP5).

CI066_HUMAN
NC score	0.003372 (rank : 1907)	θ value	8.99809 (rank : 1882)
Query Neighborhood Hits	1959	Target Neighborhood Hits	25	Shared Neighborhood Hits	9
SwissProt Accessions	Q5T8R8, Q96NB0	Gene names	C9orf66
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf66.

SPTN4_HUMAN
NC score	0.003357 (rank : 1908)	θ value	1.38821 (rank : 1458)
Query Neighborhood Hits	1959	Target Neighborhood Hits	570	Shared Neighborhood Hits	88
SwissProt Accessions	Q9H254, Q9H1K7, Q9H1K8, Q9H1K9, Q9H3G8, Q9HCD0	Gene names	SPTBN4, KIAA1642, SPTBN3
Domain Architecture
Description	Spectrin beta chain, brain 3 (Spectrin, non-erythroid beta chain 3) (Beta-IV spectrin).

PB1_HUMAN
NC score	0.003344 (rank : 1909)	θ value	3.0926 (rank : 1606)
Query Neighborhood Hits	1959	Target Neighborhood Hits	261	Shared Neighborhood Hits	58
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

MCRS1_HUMAN
NC score	0.003316 (rank : 1910)	θ value	6.88961 (rank : 1833)
Query Neighborhood Hits	1959	Target Neighborhood Hits	23	Shared Neighborhood Hits	9
SwissProt Accessions	Q96EZ8, O14742, O75497, Q6VN53	Gene names	MCRS1, MSP58
Domain Architecture
Description	Microspherule protein 1 (58 kDa microspherule protein) (Cell cycle- regulated factor p78) (MCRS2).

CD44_MOUSE
NC score	0.003258 (rank : 1911)	θ value	6.88961 (rank : 1798)
Query Neighborhood Hits	1959	Target Neighborhood Hits	64	Shared Neighborhood Hits	17
SwissProt Accessions	P15379, Q05732, Q61395, Q62060, Q62061, Q62062, Q62063, Q62408, Q62409, Q64296, Q99J14, Q9QYX8	Gene names	Cd44, Ly-24
Domain Architecture
Description	CD44 antigen precursor (Phagocytic glycoprotein 1) (PGP-1) (HUTCH-I) (Extracellular matrix receptor III) (ECMR-III) (GP90 lymphocyte homing/adhesion receptor) (Hermes antigen) (Hyaluronate receptor) (Lymphocyte antigen Ly-24).

NOTC2_MOUSE
NC score	0.003249 (rank : 1912)	θ value	1.38821 (rank : 1449)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1069	Shared Neighborhood Hits	182
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

CENG1_MOUSE
NC score	0.003214 (rank : 1913)	θ value	1.06291 (rank : 1366)
Query Neighborhood Hits	1959	Target Neighborhood Hits	531	Shared Neighborhood Hits	104
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

SOX9_HUMAN
NC score	0.003204 (rank : 1914)	θ value	5.27518 (rank : 1784)
Query Neighborhood Hits	1959	Target Neighborhood Hits	210	Shared Neighborhood Hits	75
SwissProt Accessions	P48436	Gene names	SOX9
Domain Architecture
Description	Transcription factor SOX-9.

BFSP1_HUMAN
NC score	0.003063 (rank : 1915)	θ value	3.0926 (rank : 1578)
Query Neighborhood Hits	1959	Target Neighborhood Hits	508	Shared Neighborhood Hits	58
SwissProt Accessions	Q12934, O43595, O76034, Q9HBX4	Gene names	BFSP1
Domain Architecture
Description	Filensin (Beaded filament structural protein 1) (Lens fiber cell beaded-filament structural protein CP 115) (CP115) (Lens intermediate filament-like heavy) (LIFL-H).

HORN_MOUSE
NC score	0.003056 (rank : 1916)	θ value	0.47712 (rank : 1257)
Query Neighborhood Hits	1959	Target Neighborhood Hits	218	Shared Neighborhood Hits	43
SwissProt Accessions	Q8VHD8	Gene names	Hrnr
Domain Architecture
Description	Hornerin.

PAR10_HUMAN
NC score	0.003035 (rank : 1917)	θ value	1.81305 (rank : 1503)
Query Neighborhood Hits	1959	Target Neighborhood Hits	142	Shared Neighborhood Hits	27
SwissProt Accessions	Q53GL7, Q8N2I0, Q8WV05, Q96CH7	Gene names	PARP10
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 10 (EC 2.4.2.30) (PARP-10).

ALLC_HUMAN
NC score	0.003003 (rank : 1918)	θ value	5.27518 (rank : 1710)
Query Neighborhood Hits	1959	Target Neighborhood Hits	3	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N6M5, Q53T95, Q5RL81, Q96RE6, Q9NZA7	Gene names	ALLC
Domain Architecture	No domain graphic available
Description	Probable allantoicase (EC 3.5.3.4) (Allantoate amidinohydrolase).

TUB_MOUSE
NC score	0.002980 (rank : 1919)	θ value	6.88961 (rank : 1856)
Query Neighborhood Hits	1959	Target Neighborhood Hits	28	Shared Neighborhood Hits	11
SwissProt Accessions	P50586	Gene names	Tub, Rd5
Domain Architecture
Description	Tubby protein.

SOX5_MOUSE
NC score	0.002962 (rank : 1920)	θ value	3.0926 (rank : 1622)
Query Neighborhood Hits	1959	Target Neighborhood Hits	196	Shared Neighborhood Hits	37
SwissProt Accessions	P35710, O88184, O89018	Gene names	Sox5, Sox-5
Domain Architecture
Description	Transcription factor SOX-5.

CHD4_MOUSE
NC score	0.002841 (rank : 1921)	θ value	1.38821 (rank : 1426)
Query Neighborhood Hits	1959	Target Neighborhood Hits	408	Shared Neighborhood Hits	100
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

NCOA7_MOUSE
NC score	0.002696 (rank : 1922)	θ value	4.03905 (rank : 1674)
Query Neighborhood Hits	1959	Target Neighborhood Hits	114	Shared Neighborhood Hits	18
SwissProt Accessions	Q6DFV7, Q3TAR1, Q3UNB3, Q66K05, Q6ZQM4, Q8BJ15, Q8BJ39	Gene names	Ncoa7
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 7.

KCD18_HUMAN
NC score	0.002612 (rank : 1923)	θ value	8.99809 (rank : 1914)
Query Neighborhood Hits	1959	Target Neighborhood Hits	117	Shared Neighborhood Hits	39
SwissProt Accessions	Q6PI47, Q53T21, Q6NW26, Q6PCD8, Q8N9B7, Q96N73	Gene names	KCTD18
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD18.

B3A3_HUMAN
NC score	0.002588 (rank : 1924)	θ value	1.06291 (rank : 1358)
Query Neighborhood Hits	1959	Target Neighborhood Hits	119	Shared Neighborhood Hits	43
SwissProt Accessions	P48751	Gene names	SLC4A3, AE3
Domain Architecture
Description	Anion exchange protein 3 (Neuronal band 3-like protein) (Solute carrier family 4 member 3) (Cardiac/brain band 3-like protein) (CAE3/BAE3).

GP152_HUMAN
NC score	0.002566 (rank : 1925)	θ value	2.36792 (rank : 1535)
Query Neighborhood Hits	1959	Target Neighborhood Hits	636	Shared Neighborhood Hits	157
SwissProt Accessions	Q8TDT2, Q86SM0	Gene names	GPR152, PGR5
Domain Architecture
Description	Probable G-protein coupled receptor 152 (G-protein coupled receptor PGR5).

KIF17_HUMAN
NC score	0.002551 (rank : 1926)	θ value	0.21417 (rank : 1159)
Query Neighborhood Hits	1959	Target Neighborhood Hits	365	Shared Neighborhood Hits	67
SwissProt Accessions	Q9P2E2, O95077, Q53YS6, Q5VWA9, Q6GSA8, Q8N411	Gene names	KIF17, KIAA1405, KIF3X
Domain Architecture
Description	Kinesin-like protein KIF17 (KIF3-related motor protein).

CSPG3_HUMAN
NC score	0.002534 (rank : 1927)	θ value	6.88961 (rank : 1806)
Query Neighborhood Hits	1959	Target Neighborhood Hits	676	Shared Neighborhood Hits	151
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

TR13B_HUMAN
NC score	0.002469 (rank : 1928)	θ value	8.99809 (rank : 1946)
Query Neighborhood Hits	1959	Target Neighborhood Hits	24	Shared Neighborhood Hits	8
SwissProt Accessions	O14836, Q7Z6F5	Gene names	TNFRSF13B, TACI
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 13B (Transmembrane activator and CAML interactor) (CD267 antigen).

EDA_HUMAN
NC score	0.002246 (rank : 1929)	θ value	4.03905 (rank : 1653)
Query Neighborhood Hits	1959	Target Neighborhood Hits	134	Shared Neighborhood Hits	47
SwissProt Accessions	Q92838, O75910, Q5JUM7, Q9UP77, Q9Y6L0, Q9Y6L1, Q9Y6L2, Q9Y6L3, Q9Y6L4	Gene names	EDA, ED1
Domain Architecture
Description	Ectodysplasin-A (Ectodermal dysplasia protein) (EDA protein) [Contains: Ectodysplasin-A, membrane form; Ectodysplasin-A, secreted form].

WWP1_HUMAN
NC score	0.002239 (rank : 1930)	θ value	0.0563607 (rank : 1085)
Query Neighborhood Hits	1959	Target Neighborhood Hits	262	Shared Neighborhood Hits	80
SwissProt Accessions	Q9H0M0, O00307, Q96BP4	Gene names	WWP1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1) (Atropin-1-interacting protein 5) (AIP5).

ILDR1_MOUSE
NC score	0.002135 (rank : 1931)	θ value	5.27518 (rank : 1748)
Query Neighborhood Hits	1959	Target Neighborhood Hits	33	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CBR1, Q6PFB3, Q8CB39, Q91VS0	Gene names	Ildr1
Domain Architecture	No domain graphic available
Description	Immunoglobulin-like domain-containing receptor 1 precursor.

BRD2_HUMAN
NC score	0.002038 (rank : 1932)	θ value	8.99809 (rank : 1873)
Query Neighborhood Hits	1959	Target Neighborhood Hits	242	Shared Neighborhood Hits	63
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

SL9A1_MOUSE
NC score	0.002001 (rank : 1933)	θ value	3.0926 (rank : 1618)
Query Neighborhood Hits	1959	Target Neighborhood Hits	32	Shared Neighborhood Hits	6
SwissProt Accessions	Q61165	Gene names	Slc9a1, Nhe1
Domain Architecture
Description	Sodium/hydrogen exchanger 1 (Na(+)/H(+) exchanger 1) (NHE-1) (Solute carrier family 9 member 1).

DPOD1_HUMAN
NC score	0.001934 (rank : 1934)	θ value	1.81305 (rank : 1479)
Query Neighborhood Hits	1959	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	P28340, Q8NER3, Q96H98	Gene names	POLD1, POLD
Domain Architecture
Description	DNA polymerase delta catalytic subunit (EC 2.7.7.7) (DNA polymerase subunit delta p125).

KCNQ4_HUMAN
NC score	0.001927 (rank : 1935)	θ value	5.27518 (rank : 1753)
Query Neighborhood Hits	1959	Target Neighborhood Hits	136	Shared Neighborhood Hits	28
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

PCBP4_HUMAN
NC score	0.001904 (rank : 1936)	θ value	5.27518 (rank : 1770)
Query Neighborhood Hits	1959	Target Neighborhood Hits	49	Shared Neighborhood Hits	16
SwissProt Accessions	P57723, Q96AH7	Gene names	PCBP4
Domain Architecture
Description	Poly(rC)-binding protein 4 (Alpha-CP4).

CALR_MOUSE
NC score	0.001894 (rank : 1937)	θ value	5.27518 (rank : 1723)
Query Neighborhood Hits	1959	Target Neighborhood Hits	68	Shared Neighborhood Hits	12
SwissProt Accessions	P14211	Gene names	Calr
Domain Architecture
Description	Calreticulin precursor (CRP55) (Calregulin) (HACBP) (ERp60).

CSPG3_MOUSE
NC score	0.001849 (rank : 1938)	θ value	3.0926 (rank : 1582)
Query Neighborhood Hits	1959	Target Neighborhood Hits	657	Shared Neighborhood Hits	141
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

KI13B_HUMAN
NC score	0.001673 (rank : 1939)	θ value	0.279714 (rank : 1183)
Query Neighborhood Hits	1959	Target Neighborhood Hits	492	Shared Neighborhood Hits	103
SwissProt Accessions	Q9NQT8, O75134, Q9BYJ6	Gene names	KIF13B, GAKIN, KIAA0639
Domain Architecture
Description	Kinesin-like protein KIF13B (Kinesin-like protein GAKIN).

LMBL3_HUMAN
NC score	0.001622 (rank : 1940)	θ value	5.27518 (rank : 1756)
Query Neighborhood Hits	1959	Target Neighborhood Hits	88	Shared Neighborhood Hits	25
SwissProt Accessions	Q96JM7, Q5VUM9, Q6P9B5	Gene names	L3MBTL3, KIAA1798
Domain Architecture	No domain graphic available
Description	Lethal(3)malignant brain tumor-like 3 protein (L(3)mbt-like 3 protein) (H-l(3)mbt-like protein).

FOXK2_HUMAN
NC score	0.001611 (rank : 1941)	θ value	1.81305 (rank : 1485)
Query Neighborhood Hits	1959	Target Neighborhood Hits	190	Shared Neighborhood Hits	59
SwissProt Accessions	Q01167, Q13622, Q13623, Q13624	Gene names	FOXK2, ILF, ILF1
Domain Architecture
Description	Forkhead box protein K2 (Interleukin enhancer-binding factor 1) (Cellular transcription factor ILF-1).

SP110_HUMAN
NC score	0.001574 (rank : 1942)	θ value	8.99809 (rank : 1942)
Query Neighborhood Hits	1959	Target Neighborhood Hits	141	Shared Neighborhood Hits	41
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

SEM6B_MOUSE
NC score	0.001464 (rank : 1943)	θ value	0.279714 (rank : 1197)
Query Neighborhood Hits	1959	Target Neighborhood Hits	200	Shared Neighborhood Hits	69
SwissProt Accessions	O54951	Gene names	Sema6b, Seman
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin VIB) (Sema VIB) (Semaphorin N) (Sema N).

B3A3_MOUSE
NC score	0.001449 (rank : 1944)	θ value	5.27518 (rank : 1717)
Query Neighborhood Hits	1959	Target Neighborhood Hits	112	Shared Neighborhood Hits	39
SwissProt Accessions	P16283	Gene names	Slc4a3, Ae3
Domain Architecture
Description	Anion exchange protein 3 (Neuronal band 3-like protein) (Solute carrier family 4 member 3).

FOXC1_MOUSE
NC score	0.001409 (rank : 1945)	θ value	8.99809 (rank : 1898)
Query Neighborhood Hits	1959	Target Neighborhood Hits	218	Shared Neighborhood Hits	80
SwissProt Accessions	Q61572, O88409, Q61582	Gene names	Foxc1, Fkh1, Fkhl7, Freac3, Mf1
Domain Architecture
Description	Forkhead box protein C1 (Forkhead-related protein FKHL7) (Forkhead- related transcription factor 3) (FREAC-3) (Transcription factor FKH-1) (Mesoderm/mesenchyme forkhead 1) (MF-1).

S12A5_HUMAN
NC score	0.001393 (rank : 1946)	θ value	0.813845 (rank : 1347)
Query Neighborhood Hits	1959	Target Neighborhood Hits	68	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H2X9, Q5VZ41, Q9H4Z0, Q9ULP4	Gene names	SLC12A5, KCC2, KIAA1176
Domain Architecture
Description	Solute carrier family 12 member 5 (Electroneutral potassium-chloride cotransporter 2) (Erythroid K-Cl cotransporter 2) (Neuronal K-Cl cotransporter) (hKCC2).

ETV3_MOUSE
NC score	0.001383 (rank : 1947)	θ value	3.0926 (rank : 1589)
Query Neighborhood Hits	1959	Target Neighborhood Hits	128	Shared Neighborhood Hits	43
SwissProt Accessions	Q8R4Z4, Q9QZW1	Gene names	Etv3, Mets, Pe1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

DUS8_MOUSE
NC score	0.001312 (rank : 1948)	θ value	5.27518 (rank : 1733)
Query Neighborhood Hits	1959	Target Neighborhood Hits	119	Shared Neighborhood Hits	33
SwissProt Accessions	O09112	Gene names	Dusp8, Nttp1
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Neuronal tyrosine threonine phosphatase 1).

FOXD2_MOUSE
NC score	0.001290 (rank : 1949)	θ value	0.0563607 (rank : 1071)
Query Neighborhood Hits	1959	Target Neighborhood Hits	130	Shared Neighborhood Hits	34
SwissProt Accessions	O35392	Gene names	Foxd2, Mf2
Domain Architecture
Description	Forkhead box protein D2 (Mesoderm/mesenchyme forkhead 2) (MF-2).

FOXC2_HUMAN
NC score	0.001288 (rank : 1950)	θ value	1.81305 (rank : 1484)
Query Neighborhood Hits	1959	Target Neighborhood Hits	236	Shared Neighborhood Hits	87
SwissProt Accessions	Q99958	Gene names	FOXC2, FKHL14, MFH1
Domain Architecture
Description	Forkhead box protein C2 (Forkhead-related protein FKHL14) (Mesenchyme fork head protein 1) (MFH-1 protein) (Transcription factor FKH-14).

TBX2_MOUSE
NC score	0.001180 (rank : 1951)	θ value	0.62314 (rank : 1309)
Query Neighborhood Hits	1959	Target Neighborhood Hits	97	Shared Neighborhood Hits	36
SwissProt Accessions	Q60707	Gene names	Tbx2
Domain Architecture
Description	T-box transcription factor TBX2 (T-box protein 2).

INOC1_HUMAN
NC score	0.001158 (rank : 1952)	θ value	8.99809 (rank : 1910)
Query Neighborhood Hits	1959	Target Neighborhood Hits	181	Shared Neighborhood Hits	26
SwissProt Accessions	Q9ULG1, Q9NTG6	Gene names	INOC1, KIAA1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-) (hINO80).

EMIL2_HUMAN
NC score	0.001156 (rank : 1953)	θ value	3.0926 (rank : 1588)
Query Neighborhood Hits	1959	Target Neighborhood Hits	573	Shared Neighborhood Hits	98
SwissProt Accessions	Q9BXX0, Q8NBH3, Q96JQ4	Gene names	EMILIN2
Domain Architecture
Description	EMILIN-2 precursor (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Protein FOAP-10).

PSD4_MOUSE
NC score	0.001061 (rank : 1954)	θ value	8.99809 (rank : 1931)
Query Neighborhood Hits	1959	Target Neighborhood Hits	78	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BLR5, Q3TE33, Q3TQF5, Q3UD59, Q3UFH9, Q80V44	Gene names	Psd4
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4).

RECQ4_MOUSE
NC score	0.001004 (rank : 1955)	θ value	4.03905 (rank : 1685)
Query Neighborhood Hits	1959	Target Neighborhood Hits	206	Shared Neighborhood Hits	48
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

EYA4_MOUSE
NC score	0.000981 (rank : 1956)	θ value	6.88961 (rank : 1818)
Query Neighborhood Hits	1959	Target Neighborhood Hits	74	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Z191	Gene names	Eya4
Domain Architecture
Description	Eyes absent homolog 4 (EC 3.1.3.48).

KCNC3_HUMAN
NC score	0.000961 (rank : 1957)	θ value	1.38821 (rank : 1442)
Query Neighborhood Hits	1959	Target Neighborhood Hits	256	Shared Neighborhood Hits	83
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

S12A5_MOUSE
NC score	0.000808 (rank : 1958)	θ value	1.06291 (rank : 1404)
Query Neighborhood Hits	1959	Target Neighborhood Hits	59	Shared Neighborhood Hits	5
SwissProt Accessions	Q91V14, Q9Z0M7	Gene names	Slc12a5, Kcc2
Domain Architecture
Description	Solute carrier family 12 member 5 (Electroneutral potassium-chloride cotransporter 2) (K-Cl cotransporter 2) (Neuronal K-Cl cotransporter) (mKCC2).

FOXE2_HUMAN
NC score	0.000798 (rank : 1959)	θ value	8.99809 (rank : 1899)
Query Neighborhood Hits	1959	Target Neighborhood Hits	236	Shared Neighborhood Hits	82
SwissProt Accessions	Q99526	Gene names	FOXE2
Domain Architecture
Description	Forkhead box protein E2 (HNF-3/fork head-like protein 5) (HFKL5) (HFKH4).

KCNQ1_MOUSE
NC score	0.000688 (rank : 1960)	θ value	2.36792 (rank : 1542)
Query Neighborhood Hits	1959	Target Neighborhood Hits	175	Shared Neighborhood Hits	51
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

TSYL1_MOUSE
NC score	0.000564 (rank : 1961)	θ value	6.88961 (rank : 1855)
Query Neighborhood Hits	1959	Target Neighborhood Hits	105	Shared Neighborhood Hits	33
SwissProt Accessions	O88852, Q3TKW0	Gene names	Tspyl1, Tspyl
Domain Architecture
Description	Testis-specific Y-encoded-like protein 1 (TSPY-like 1).

CRIP3_HUMAN
NC score	0.000480 (rank : 1962)	θ value	8.99809 (rank : 1889)
Query Neighborhood Hits	1959	Target Neighborhood Hits	104	Shared Neighborhood Hits	15
SwissProt Accessions	Q6Q6R5, Q5T043, Q6Q6R4, Q6Q6R6, Q6Q6R7	Gene names	CRIP3
Domain Architecture	No domain graphic available
Description	Cysteine-rich protein 3 (CRP3) (Chromosome 6 LIM-only protein) (h6LIMo).

NBEA_MOUSE
NC score	0.000478 (rank : 1963)	θ value	3.0926 (rank : 1605)
Query Neighborhood Hits	1959	Target Neighborhood Hits	225	Shared Neighborhood Hits	29
SwissProt Accessions	Q9EPN1, Q8C931, Q9EPM9, Q9EPN0, Q9WVM9	Gene names	Nbea, Lyst2
Domain Architecture
Description	Protein neurobeachin (Lysosomal-trafficking regulator 2).

SI1L2_MOUSE
NC score	0.000456 (rank : 1964)	θ value	4.03905 (rank : 1692)
Query Neighborhood Hits	1959	Target Neighborhood Hits	124	Shared Neighborhood Hits	20
SwissProt Accessions	Q80TE4, Q6PDY1	Gene names	Sipa1l2, Kiaa0545
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

FOXR1_HUMAN
NC score	0.000368 (rank : 1965)	θ value	0.21417 (rank : 1154)
Query Neighborhood Hits	1959	Target Neighborhood Hits	85	Shared Neighborhood Hits	13
SwissProt Accessions	Q6PIV2, Q86UT9, Q8IXX2	Gene names	FOXR1, DLNB13, FOXN5
Domain Architecture	No domain graphic available
Description	Forkhead box protein R1 (Forkhead box protein N5).

SEM6D_MOUSE
NC score	0.000332 (rank : 1966)	θ value	5.27518 (rank : 1782)
Query Neighborhood Hits	1959	Target Neighborhood Hits	161	Shared Neighborhood Hits	51
SwissProt Accessions	Q76KF0, Q76KF1, Q76KF2, Q76KF3, Q76KF4, Q80TD0	Gene names	Sema6d, Kiaa1479
Domain Architecture	No domain graphic available
Description	Semaphorin-6D precursor.

KIF17_MOUSE
NC score	0.000325 (rank : 1967)	θ value	6.88961 (rank : 1830)
Query Neighborhood Hits	1959	Target Neighborhood Hits	452	Shared Neighborhood Hits	67
SwissProt Accessions	Q99PW8	Gene names	Kif17
Domain Architecture
Description	Kinesin-like protein KIF17 (MmKIF17).

LRP11_HUMAN
NC score	0.000308 (rank : 1968)	θ value	6.88961 (rank : 1831)
Query Neighborhood Hits	1959	Target Neighborhood Hits	82	Shared Neighborhood Hits	8
SwissProt Accessions	Q86VZ4, Q5VYC0, Q96SN6	Gene names	LRP11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.

RGL2_MOUSE
NC score	0.000266 (rank : 1969)	θ value	4.03905 (rank : 1686)
Query Neighborhood Hits	1959	Target Neighborhood Hits	51	Shared Neighborhood Hits	12
SwissProt Accessions	Q61193, Q9QUJ2	Gene names	Rgl2, Rab2l, Rlf
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator-like 2 (RalGDS-like factor) (RAS-associated protein RAB2L).

UBP21_MOUSE
NC score	0.000091 (rank : 1970)	θ value	0.0563607 (rank : 1082)
Query Neighborhood Hits	1959	Target Neighborhood Hits	101	Shared Neighborhood Hits	16
SwissProt Accessions	Q9QZL6, Q9D0R1	Gene names	Usp21, Usp23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21).

HSPB8_HUMAN
NC score	0.000089 (rank : 1971)	θ value	5.27518 (rank : 1746)
Query Neighborhood Hits	1959	Target Neighborhood Hits	25	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UJY1, Q6FIH3, Q9UKS3	Gene names	HSPB8, CRYAC, E2IG1, HSP22
Domain Architecture
Description	Heat-shock protein beta-8 (HspB8) (Alpha crystallin C chain) (Small stress protein-like protein HSP22) (E2-induced gene 1 protein) (Protein kinase H11).

FOXL2_MOUSE
NC score	0.000083 (rank : 1972)	θ value	0.813845 (rank : 1327)
Query Neighborhood Hits	1959	Target Neighborhood Hits	151	Shared Neighborhood Hits	54
SwissProt Accessions	O88470, Q8K3X9	Gene names	Foxl2, Pfrk
Domain Architecture	No domain graphic available
Description	Forkhead box protein L2 (Pituitary forkhead factor) (P-Frk).

PGCB_HUMAN
NC score	0.000062 (rank : 1973)	θ value	0.62314 (rank : 1302)
Query Neighborhood Hits	1959	Target Neighborhood Hits	478	Shared Neighborhood Hits	83
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

NBEA_HUMAN
NC score	-0.000075 (rank : 1974)	θ value	4.03905 (rank : 1673)
Query Neighborhood Hits	1959	Target Neighborhood Hits	186	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NFP9, Q9HCM8, Q9NSU1, Q9NW98, Q9Y6J1	Gene names	NBEA, BCL8B, KIAA1544, LYST2
Domain Architecture
Description	Protein neurobeachin (Lysosomal-trafficking regulator 2) (Protein BCL8B).

DPOLL_HUMAN
NC score	-0.000091 (rank : 1975)	θ value	8.99809 (rank : 1894)
Query Neighborhood Hits	1959	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UGP5, Q5JQP5, Q6NUM2, Q9HA10, Q9HB35	Gene names	POLL
Domain Architecture
Description	DNA polymerase lambda (EC 2.7.7.7) (EC 4.2.99.-) (Pol Lambda) (DNA polymerase kappa) (DNA polymerase beta-2) (Pol beta2).

L2GL1_HUMAN
NC score	-0.000091 (rank : 1976)	θ value	4.03905 (rank : 1666)
Query Neighborhood Hits	1959	Target Neighborhood Hits	64	Shared Neighborhood Hits	9
SwissProt Accessions	Q15334, O00188, Q58F11, Q86UK6	Gene names	LLGL1, HUGL
Domain Architecture	No domain graphic available
Description	Lethal(2) giant larvae protein homolog 1 (LLGL) (Human homolog to the D-lgl gene) (Hugl-1) (DLG4).

PCBP4_MOUSE
NC score	-0.000153 (rank : 1977)	θ value	6.88961 (rank : 1840)
Query Neighborhood Hits	1959	Target Neighborhood Hits	46	Shared Neighborhood Hits	11
SwissProt Accessions	P57724, Q91VR3	Gene names	Pcbp4
Domain Architecture
Description	Poly(rC)-binding protein 4 (Alpha-CP4).

SORC2_MOUSE
NC score	-0.000196 (rank : 1978)	θ value	4.03905 (rank : 1694)
Query Neighborhood Hits	1959	Target Neighborhood Hits	32	Shared Neighborhood Hits	9
SwissProt Accessions	Q9EPR5	Gene names	Sorcs2
Domain Architecture
Description	VPS10 domain-containing receptor SorCS2 precursor.

KCNQ2_MOUSE
NC score	-0.000204 (rank : 1979)	θ value	2.36792 (rank : 1543)
Query Neighborhood Hits	1959	Target Neighborhood Hits	163	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Z351, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350	Gene names	Kcnq2, Kqt2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNK4_MOUSE
NC score	-0.000241 (rank : 1980)	θ value	6.88961 (rank : 1829)
Query Neighborhood Hits	1959	Target Neighborhood Hits	118	Shared Neighborhood Hits	33
SwissProt Accessions	O88454	Gene names	Kcnk4, Traak
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK).

SEM6D_HUMAN
NC score	-0.000275 (rank : 1981)	θ value	6.88961 (rank : 1845)
Query Neighborhood Hits	1959	Target Neighborhood Hits	169	Shared Neighborhood Hits	48
SwissProt Accessions	Q8NFY4, Q8NFY3, Q8NFY5, Q8NFY6, Q8NFY7, Q9P249	Gene names	SEMA6D, KIAA1479
Domain Architecture	No domain graphic available
Description	Semaphorin-6D precursor.

SOX17_HUMAN
NC score	-0.000501 (rank : 1982)	θ value	1.38821 (rank : 1457)
Query Neighborhood Hits	1959	Target Neighborhood Hits	108	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H6I2	Gene names	SOX17
Domain Architecture
Description	Transcription factor SOX-17.

L2GL1_MOUSE
NC score	-0.000619 (rank : 1983)	θ value	8.99809 (rank : 1919)
Query Neighborhood Hits	1959	Target Neighborhood Hits	70	Shared Neighborhood Hits	8
SwissProt Accessions	Q80Y17, Q61856, Q7TNV3, Q8BN92	Gene names	Llgl1, Llglh
Domain Architecture	No domain graphic available
Description	Lethal(2) giant larvae protein homolog 1 (LLGL) (Mlgl) (Mgl-1).

FOXL2_HUMAN
NC score	-0.000670 (rank : 1984)	θ value	1.38821 (rank : 1432)
Query Neighborhood Hits	1959	Target Neighborhood Hits	142	Shared Neighborhood Hits	43
SwissProt Accessions	P58012, Q4ZGJ3	Gene names	FOXL2
Domain Architecture
Description	Forkhead box protein L2.

HSPB8_MOUSE
NC score	-0.000768 (rank : 1985)	θ value	8.99809 (rank : 1906)
Query Neighborhood Hits	1959	Target Neighborhood Hits	34	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JK92	Gene names	Hspb8, Cryac, Hsp22
Domain Architecture
Description	Heat-shock protein beta-8 (HspB8) (Alpha crystallin C chain) (Small stress protein-like protein HSP22).

CHD3_HUMAN
NC score	-0.000814 (rank : 1986)	θ value	3.0926 (rank : 1581)
Query Neighborhood Hits	1959	Target Neighborhood Hits	397	Shared Neighborhood Hits	79
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

REEP2_MOUSE
NC score	-0.000887 (rank : 1987)	θ value	5.27518 (rank : 1777)
Query Neighborhood Hits	1959	Target Neighborhood Hits	31	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VCD6	Gene names	Reep2
Domain Architecture	No domain graphic available
Description	Receptor expression-enhancing protein 2.

TRPM6_HUMAN
NC score	-0.000898 (rank : 1988)	θ value	1.06291 (rank : 1413)
Query Neighborhood Hits	1959	Target Neighborhood Hits	91	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BX84, Q6VPR8, Q6VPR9, Q6VPS0, Q6VPS1, Q6VPS2	Gene names	TRPM6, CHAK2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6).

SOAT1_HUMAN
NC score	-0.000942 (rank : 1989)	θ value	8.99809 (rank : 1941)
Query Neighborhood Hits	1959	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	P35610, Q8N1E4	Gene names	SOAT1, ACACT, ACACT1, ACAT, ACAT1, SOAT, STAT
Domain Architecture
Description	Sterol O-acyltransferase 1 (EC 2.3.1.26) (Cholesterol acyltransferase 1) (Acyl coenzyme A:cholesterol acyltransferase 1) (ACAT-1).

SI1L2_HUMAN
NC score	-0.001000 (rank : 1990)	θ value	6.88961 (rank : 1847)
Query Neighborhood Hits	1959	Target Neighborhood Hits	131	Shared Neighborhood Hits	18
SwissProt Accessions	Q9P2F8, Q5VXR7, Q5VXR8, Q641Q4, Q8NA38, Q96DZ3, Q9H9F6	Gene names	SIPA1L2, KIAA1389
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

UBP51_HUMAN
NC score	-0.001014 (rank : 1991)	θ value	5.27518 (rank : 1789)
Query Neighborhood Hits	1959	Target Neighborhood Hits	162	Shared Neighborhood Hits	56
SwissProt Accessions	Q70EK9, Q8IWJ8	Gene names	USP51
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51).

KCNH1_MOUSE
NC score	-0.001016 (rank : 1992)	θ value	8.99809 (rank : 1915)
Query Neighborhood Hits	1959	Target Neighborhood Hits	94	Shared Neighborhood Hits	14
SwissProt Accessions	Q60603	Gene names	Kcnh1, Eag
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (EAG1) (m-eag).

NRL_HUMAN
NC score	-0.001044 (rank : 1993)	θ value	6.88961 (rank : 1836)
Query Neighborhood Hits	1959	Target Neighborhood Hits	39	Shared Neighborhood Hits	6
SwissProt Accessions	P54845	Gene names	NRL
Domain Architecture
Description	Neural retina-specific leucine zipper protein (NRL) (D14S46E).

MEFV_MOUSE
NC score	-0.001129 (rank : 1994)	θ value	5.27518 (rank : 1759)
Query Neighborhood Hits	1959	Target Neighborhood Hits	236	Shared Neighborhood Hits	40
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

HNF3B_MOUSE
NC score	-0.001329 (rank : 1995)	θ value	3.0926 (rank : 1591)
Query Neighborhood Hits	1959	Target Neighborhood Hits	112	Shared Neighborhood Hits	31
SwissProt Accessions	P35583, Q60602	Gene names	Foxa2, Hnf3b, Tcf-3b, Tcf3b
Domain Architecture
Description	Hepatocyte nuclear factor 3-beta (HNF-3B) (Forkhead box protein A2).

TBX10_MOUSE
NC score	-0.001543 (rank : 1996)	θ value	1.81305 (rank : 1514)
Query Neighborhood Hits	1959	Target Neighborhood Hits	47	Shared Neighborhood Hits	11
SwissProt Accessions	Q810F8, O54841, Q6QH75	Gene names	Tbx10, Tbx13, Tbx7
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX10 (T-box protein 10) (T-box protein 13) (MmTBX7).

DDX46_HUMAN
NC score	-0.001557 (rank : 1997)	θ value	6.88961 (rank : 1813)
Query Neighborhood Hits	1959	Target Neighborhood Hits	357	Shared Neighborhood Hits	56
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

DDX46_MOUSE
NC score	-0.001613 (rank : 1998)	θ value	5.27518 (rank : 1730)
Query Neighborhood Hits	1959	Target Neighborhood Hits	358	Shared Neighborhood Hits	63
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

CAN12_HUMAN
NC score	-0.001677 (rank : 1999)	θ value	4.03905 (rank : 1641)
Query Neighborhood Hits	1959	Target Neighborhood Hits	47	Shared Neighborhood Hits	5
SwissProt Accessions	Q6ZSI9	Gene names	CAPN12
Domain Architecture	No domain graphic available
Description	Calpain-12 (EC 3.4.22.-).

KLD8B_MOUSE
NC score	-0.001850 (rank : 2000)	θ value	0.365318 (rank : 1218)
Query Neighborhood Hits	1959	Target Neighborhood Hits	80	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D2D9	Gene names	Klhdc8b
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 8B.

TREF1_MOUSE
NC score	-0.001852 (rank : 2001)	θ value	4.03905 (rank : 1701)
Query Neighborhood Hits	1959	Target Neighborhood Hits	682	Shared Neighborhood Hits	99
SwissProt Accessions	Q8BXJ2, Q6PCQ4, Q80X25, Q810H8, Q8BY31	Gene names	Trerf1
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132).

FOXL1_HUMAN
NC score	-0.001868 (rank : 2002)	θ value	2.36792 (rank : 1534)
Query Neighborhood Hits	1959	Target Neighborhood Hits	114	Shared Neighborhood Hits	31
SwissProt Accessions	Q12952, Q9H242	Gene names	FOXL1, FKHL11, FREAC7
Domain Architecture
Description	Forkhead box protein L1 (Forkhead-related protein FKHL11) (Forkhead- related transcription factor 7) (FREAC-7).

SOX18_HUMAN
NC score	-0.001981 (rank : 2003)	θ value	2.36792 (rank : 1566)
Query Neighborhood Hits	1959	Target Neighborhood Hits	106	Shared Neighborhood Hits	23
SwissProt Accessions	P35713, Q9NPH8	Gene names	SOX18
Domain Architecture
Description	Transcription factor SOX-18.

BNC2_HUMAN
NC score	-0.002221 (rank : 2004)	θ value	8.99809 (rank : 1871)
Query Neighborhood Hits	1959	Target Neighborhood Hits	439	Shared Neighborhood Hits	47
SwissProt Accessions	Q6ZN30, Q6T3A3, Q8NAR2, Q9H6J0, Q9NXV0	Gene names	BNC2
Domain Architecture	No domain graphic available
Description	Zinc finger protein basonuclin-2.

CAN12_MOUSE
NC score	-0.002312 (rank : 2005)	θ value	6.88961 (rank : 1797)
Query Neighborhood Hits	1959	Target Neighborhood Hits	56	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ER56, Q9ER53, Q9ER54, Q9ER55	Gene names	Capn12
Domain Architecture
Description	Calpain-12 (EC 3.4.22.-).

HNF3B_HUMAN
NC score	-0.002354 (rank : 2006)	θ value	8.99809 (rank : 1905)
Query Neighborhood Hits	1959	Target Neighborhood Hits	106	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y261, Q8WUW4, Q96DF7	Gene names	FOXA2, HNF3B, TCF3B
Domain Architecture
Description	Hepatocyte nuclear factor 3-beta (HNF-3B) (Forkhead box protein A2).

KCNQ2_HUMAN
NC score	-0.002370 (rank : 2007)	θ value	8.99809 (rank : 1916)
Query Neighborhood Hits	1959	Target Neighborhood Hits	114	Shared Neighborhood Hits	21
SwissProt Accessions	O43526, O43796, O75580, O95845, Q5VYT8, Q96J59, Q99454	Gene names	KCNQ2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (KQT-like 2).

CD6_HUMAN
NC score	-0.002405 (rank : 2008)	θ value	6.88961 (rank : 1799)
Query Neighborhood Hits	1959	Target Neighborhood Hits	65	Shared Neighborhood Hits	13
SwissProt Accessions	P30203, Q9UMF2, Q9Y4K7, Q9Y4K8, Q9Y4K9, Q9Y4L0	Gene names	CD6
Domain Architecture
Description	T-cell differentiation antigen CD6 precursor (T12) (TP120).

ANGL6_MOUSE
NC score	-0.002606 (rank : 2009)	θ value	0.62314 (rank : 1284)
Query Neighborhood Hits	1959	Target Neighborhood Hits	63	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R0Z6	Gene names	Angptl6, Agf
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 6 precursor (Angiopoietin-like 6) (Angiopoietin-related growth factor).

BNC2_MOUSE
NC score	-0.002608 (rank : 2010)	θ value	8.99809 (rank : 1872)
Query Neighborhood Hits	1959	Target Neighborhood Hits	456	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BMQ3, Q6T3A4	Gene names	Bnc2
Domain Architecture	No domain graphic available
Description	Zinc finger protein basonuclin-2.

C1QR1_HUMAN
NC score	-0.002633 (rank : 2011)	θ value	8.99809 (rank : 1876)
Query Neighborhood Hits	1959	Target Neighborhood Hits	493	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

MMP21_HUMAN
NC score	-0.002658 (rank : 2012)	θ value	1.81305 (rank : 1501)
Query Neighborhood Hits	1959	Target Neighborhood Hits	76	Shared Neighborhood Hits	15
SwissProt Accessions	Q8N119, Q8NG02	Gene names	MMP21
Domain Architecture	No domain graphic available
Description	Matrix metalloproteinase-21 precursor (EC 3.4.24.-) (MMP-21).

PEF1_HUMAN
NC score	-0.002680 (rank : 2013)	θ value	6.88961 (rank : 1841)
Query Neighborhood Hits	1959	Target Neighborhood Hits	135	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UBV8	Gene names	PEF1, ABP32
Domain Architecture	No domain graphic available
Description	Peflin (PEF protein with a long N-terminal hydrophobic domain) (Penta- EF hand domain-containing protein 1).

RAVR1_MOUSE
NC score	-0.002789 (rank : 2014)	θ value	5.27518 (rank : 1776)
Query Neighborhood Hits	1959	Target Neighborhood Hits	179	Shared Neighborhood Hits	28
SwissProt Accessions	Q9CW46, Q5DTT6, Q811K0, Q8C3Z1, Q8CA14	Gene names	Raver1, Kiaa1978
Domain Architecture	No domain graphic available
Description	Ribonucleoprotein PTB-binding 1 (Protein raver-1).

HXA3_MOUSE
NC score	-0.003033 (rank : 2015)	θ value	1.81305 (rank : 1491)
Query Neighborhood Hits	1959	Target Neighborhood Hits	558	Shared Neighborhood Hits	150
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

KCNC3_MOUSE
NC score	-0.003242 (rank : 2016)	θ value	1.38821 (rank : 1443)
Query Neighborhood Hits	1959	Target Neighborhood Hits	173	Shared Neighborhood Hits	36
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

SFRS2_HUMAN
NC score	-0.003261 (rank : 2017)	θ value	1.06291 (rank : 1407)
Query Neighborhood Hits	1959	Target Neighborhood Hits	222	Shared Neighborhood Hits	31
SwissProt Accessions	Q01130	Gene names	SFRS2
Domain Architecture
Description	Splicing factor, arginine/serine-rich 2 (Splicing factor SC35) (SC-35) (Splicing component, 35 kDa) (Protein PR264).

SFRS2_MOUSE
NC score	-0.003261 (rank : 2018)	θ value	1.06291 (rank : 1408)
Query Neighborhood Hits	1959	Target Neighborhood Hits	222	Shared Neighborhood Hits	31
SwissProt Accessions	Q62093, Q542L3, Q60701	Gene names	Sfrs2, Pr264, Sfrs10
Domain Architecture
Description	Splicing factor, arginine/serine-rich 2 (Splicing factor SC35) (SC-35) (Splicing component, 35 kDa) (Protein PR264) (Putative myelin regulatory factor 1) (MRF-1).

KLD8B_HUMAN
NC score	-0.003335 (rank : 2019)	θ value	2.36792 (rank : 1544)
Query Neighborhood Hits	1959	Target Neighborhood Hits	80	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IXV7	Gene names	KLHDC8B
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 8B.

HXA3_HUMAN
NC score	-0.003524 (rank : 2020)	θ value	3.0926 (rank : 1592)
Query Neighborhood Hits	1959	Target Neighborhood Hits	535	Shared Neighborhood Hits	135
SwissProt Accessions	O43365	Gene names	HOXA3, HOX1E
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1E).

SC6A5_HUMAN
NC score	-0.003556 (rank : 2021)	θ value	0.813845 (rank : 1348)
Query Neighborhood Hits	1959	Target Neighborhood Hits	69	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y345, O95288, Q9BX77	Gene names	SLC6A5, GLYT2
Domain Architecture
Description	Sodium- and chloride-dependent glycine transporter 2 (GlyT2) (GlyT-2) (Solute carrier family 6 member 5).

PZRN3_MOUSE
NC score	-0.003690 (rank : 2022)	θ value	3.0926 (rank : 1612)
Query Neighborhood Hits	1959	Target Neighborhood Hits	447	Shared Neighborhood Hits	61
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

KIFC2_HUMAN
NC score	-0.003725 (rank : 2023)	θ value	1.81305 (rank : 1497)
Query Neighborhood Hits	1959	Target Neighborhood Hits	237	Shared Neighborhood Hits	29
SwissProt Accessions	Q96AC6	Gene names	KIFC2
Domain Architecture
Description	Kinesin-like protein KIFC2.

AT11C_HUMAN
NC score	-0.003889 (rank : 2024)	θ value	3.0926 (rank : 1576)
Query Neighborhood Hits	1959	Target Neighborhood Hits	89	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NB49, Q5JT69, Q5JT70, Q5JT71, Q5JT72, Q5JT73, Q6ZND5, Q6ZU50, Q6ZUP7, Q70IJ9, Q70IK0, Q8WX24	Gene names	ATP11C, ATPIG, ATPIQ
Domain Architecture	No domain graphic available
Description	Probable phospholipid-transporting ATPase IG (EC 3.6.3.1) (ATPase class I type 11C) (ATPase IG) (ATPase IQ) (ATPase class VI type 11C).

PZRN3_HUMAN
NC score	-0.003896 (rank : 2025)	θ value	5.27518 (rank : 1775)
Query Neighborhood Hits	1959	Target Neighborhood Hits	461	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

FOXI2_MOUSE
NC score	-0.004036 (rank : 2026)	θ value	4.03905 (rank : 1657)
Query Neighborhood Hits	1959	Target Neighborhood Hits	89	Shared Neighborhood Hits	17
SwissProt Accessions	Q3I5G5, Q8BIK9	Gene names	Foxi2
Domain Architecture	No domain graphic available
Description	Forkhead box protein I2.

PDE9A_HUMAN
NC score	-0.004046 (rank : 2027)	θ value	0.813845 (rank : 1338)
Query Neighborhood Hits	1959	Target Neighborhood Hits	93	Shared Neighborhood Hits	5
SwissProt Accessions	O76083, O75490, O75491, O95225, Q86SF7, Q86SI6, Q86SJ3, Q86WN3, Q86WN4, Q86WN5, Q86WN6, Q86WN7, Q86WN8, Q86WN9, Q86WP0	Gene names	PDE9A
Domain Architecture
Description	High-affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (EC 3.1.4.35).

NMDE3_MOUSE
NC score	-0.004104 (rank : 2028)	θ value	8.99809 (rank : 1922)
Query Neighborhood Hits	1959	Target Neighborhood Hits	86	Shared Neighborhood Hits	25
SwissProt Accessions	Q01098	Gene names	Grin2c
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 3 precursor (N-methyl D- aspartate receptor subtype 2C) (NR2C) (NMDAR2C).

FOG1_MOUSE
NC score	-0.004108 (rank : 2029)	θ value	1.06291 (rank : 1374)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1237	Shared Neighborhood Hits	308
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

PZRN4_HUMAN
NC score	-0.004145 (rank : 2030)	θ value	4.03905 (rank : 1683)
Query Neighborhood Hits	1959	Target Neighborhood Hits	438	Shared Neighborhood Hits	40
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

KIF1C_HUMAN
NC score	-0.004244 (rank : 2031)	θ value	8.99809 (rank : 1917)
Query Neighborhood Hits	1959	Target Neighborhood Hits	128	Shared Neighborhood Hits	28
SwissProt Accessions	O43896, O75186	Gene names	KIF1C, KIAA0706
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF1C.

UBP49_MOUSE
NC score	-0.004364 (rank : 2032)	θ value	6.88961 (rank : 1857)
Query Neighborhood Hits	1959	Target Neighborhood Hits	91	Shared Neighborhood Hits	10
SwissProt Accessions	Q6P9L4	Gene names	Usp49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

KCD12_HUMAN
NC score	-0.004473 (rank : 2033)	θ value	8.99809 (rank : 1913)
Query Neighborhood Hits	1959	Target Neighborhood Hits	64	Shared Neighborhood Hits	7
SwissProt Accessions	Q96CX2	Gene names	KCTD12, C13orf2, KIAA1778, PFET1
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD12 (Pfetin) (Predominantly fetal expressed T1 domain).

ZHX3_MOUSE
NC score	-0.004535 (rank : 2034)	θ value	8.99809 (rank : 1957)
Query Neighborhood Hits	1959	Target Neighborhood Hits	321	Shared Neighborhood Hits	26
SwissProt Accessions	Q8C0Q2, Q80U14	Gene names	Zhx3, Kiaa0395, Tix1
Domain Architecture
Description	Zinc finger and homeodomain protein 3 (Triple homeobox protein 1).

ADA19_MOUSE
NC score	-0.004553 (rank : 2035)	θ value	2.36792 (rank : 1520)
Query Neighborhood Hits	1959	Target Neighborhood Hits	315	Shared Neighborhood Hits	52
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

GP162_HUMAN
NC score	-0.004693 (rank : 2036)	θ value	1.38821 (rank : 1434)
Query Neighborhood Hits	1959	Target Neighborhood Hits	244	Shared Neighborhood Hits	4
SwissProt Accessions	Q16538, Q16664, Q59EH5, Q66K56	Gene names	GPR162, GRCA
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 162 (Gene-rich cluster gene A protein).

41_MOUSE
NC score	-0.004774 (rank : 2037)	θ value	5.27518 (rank : 1709)
Query Neighborhood Hits	1959	Target Neighborhood Hits	184	Shared Neighborhood Hits	34
SwissProt Accessions	P48193, Q68FF1, Q6NVF5	Gene names	Epb41, Epb4.1
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (4.1R).

KR261_HUMAN
NC score	-0.004782 (rank : 2038)	θ value	8.99809 (rank : 1918)
Query Neighborhood Hits	1959	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	Q6PEX3	Gene names	KRTAP26-1, KAP26.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 26-1.

ATBF1_MOUSE
NC score	-0.005170 (rank : 2039)	θ value	3.0926 (rank : 1577)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1841	Shared Neighborhood Hits	325
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

TMPSD_MOUSE
NC score	-0.005179 (rank : 2040)	θ value	0.0736092 (rank : 1098)
Query Neighborhood Hits	1959	Target Neighborhood Hits	334	Shared Neighborhood Hits	82
SwissProt Accessions	Q5U405, Q8CFE0, Q91VQ8	Gene names	Tmprss13, Msp
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

TMPSD_HUMAN
NC score	-0.005467 (rank : 2041)	θ value	0.47712 (rank : 1276)
Query Neighborhood Hits	1959	Target Neighborhood Hits	333	Shared Neighborhood Hits	72
SwissProt Accessions	Q9BYE2, Q86YM4, Q96JY8, Q9BYE1	Gene names	TMPRSS13, MSP, TMPRSS11
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

DDX18_MOUSE
NC score	-0.005647 (rank : 2042)	θ value	4.03905 (rank : 1649)
Query Neighborhood Hits	1959	Target Neighborhood Hits	115	Shared Neighborhood Hits	20
SwissProt Accessions	Q8K363, Q3MIB0, Q8BVZ2, Q9D2E0	Gene names	Ddx18
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18).

DDX20_MOUSE
NC score	-0.005796 (rank : 2043)	θ value	5.27518 (rank : 1729)
Query Neighborhood Hits	1959	Target Neighborhood Hits	177	Shared Neighborhood Hits	47
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

DDX54_MOUSE
NC score	-0.005812 (rank : 2044)	θ value	1.38821 (rank : 1428)
Query Neighborhood Hits	1959	Target Neighborhood Hits	124	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K4L0	Gene names	Ddx54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54).

K2C7_HUMAN
NC score	-0.005849 (rank : 2045)	θ value	1.06291 (rank : 1387)
Query Neighborhood Hits	1959	Target Neighborhood Hits	369	Shared Neighborhood Hits	24
SwissProt Accessions	P08729, Q92676, Q9BUD8, Q9Y3R7	Gene names	KRT7, SCL
Domain Architecture
Description	Keratin, type II cytoskeletal 7 (Cytokeratin-7) (CK-7) (Keratin-7) (K7) (Sarcolectin).

GP162_MOUSE
NC score	-0.005966 (rank : 2046)	θ value	4.03905 (rank : 1659)
Query Neighborhood Hits	1959	Target Neighborhood Hits	242	Shared Neighborhood Hits	3
SwissProt Accessions	Q3UN16, O88835	Gene names	Gpr162
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 162.

CSTN3_MOUSE
NC score	-0.005985 (rank : 2047)	θ value	8.99809 (rank : 1891)
Query Neighborhood Hits	1959	Target Neighborhood Hits	142	Shared Neighborhood Hits	9
SwissProt Accessions	Q99JH7	Gene names	Clstn3, Cs3, Cstn3
Domain Architecture
Description	Calsyntenin-3 precursor.

DDX18_HUMAN
NC score	-0.006063 (rank : 2048)	θ value	6.88961 (rank : 1812)
Query Neighborhood Hits	1959	Target Neighborhood Hits	124	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NVP1, Q6IAU4, Q92732, Q9BQB7	Gene names	DDX18
Domain Architecture
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb).

CSTN3_HUMAN
NC score	-0.006372 (rank : 2049)	θ value	8.99809 (rank : 1890)
Query Neighborhood Hits	1959	Target Neighborhood Hits	145	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BQT9, O94831	Gene names	CLSTN3, CS3, KIAA0726
Domain Architecture
Description	Calsyntenin-3 precursor.

ITAE_MOUSE
NC score	-0.006442 (rank : 2050)	θ value	6.88961 (rank : 1828)
Query Neighborhood Hits	1959	Target Neighborhood Hits	73	Shared Neighborhood Hits	5
SwissProt Accessions	Q60677	Gene names	Itgae
Domain Architecture
Description	Integrin alpha-E precursor (Integrin alpha M290) (CD103 antigen) [Contains: Integrin alpha-E light chain; Integrin alpha-E heavy chain].

FOG1_HUMAN
NC score	-0.006491 (rank : 2051)	θ value	0.0563607 (rank : 1070)
Query Neighborhood Hits	1959	Target Neighborhood Hits	981	Shared Neighborhood Hits	188
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

ADAM9_MOUSE
NC score	-0.006813 (rank : 2052)	θ value	1.38821 (rank : 1421)
Query Neighborhood Hits	1959	Target Neighborhood Hits	325	Shared Neighborhood Hits	42
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

DTX3_MOUSE
NC score	-0.007003 (rank : 2053)	θ value	6.88961 (rank : 1816)
Query Neighborhood Hits	1959	Target Neighborhood Hits	202	Shared Neighborhood Hits	12
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

RING1_MOUSE
NC score	-0.007069 (rank : 2054)	θ value	4.03905 (rank : 1687)
Query Neighborhood Hits	1959	Target Neighborhood Hits	220	Shared Neighborhood Hits	22
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

BMP6_HUMAN
NC score	-0.007555 (rank : 2055)	θ value	5.27518 (rank : 1722)
Query Neighborhood Hits	1959	Target Neighborhood Hits	82	Shared Neighborhood Hits	4
SwissProt Accessions	P22004	Gene names	BMP6, VGR
Domain Architecture
Description	Bone morphogenetic protein 6 precursor (BMP-6).

TITF1_MOUSE
NC score	-0.007753 (rank : 2056)	θ value	0.47712 (rank : 1273)
Query Neighborhood Hits	1959	Target Neighborhood Hits	335	Shared Neighborhood Hits	31
SwissProt Accessions	P50220	Gene names	Titf1, Nkx-2.1, Nkx2-1, Ttf1
Domain Architecture	No domain graphic available
Description	Thyroid transcription factor 1 (Thyroid nuclear factor 1) (TTF-1) (Homeobox protein Nkx-2.1).

ZEP1_MOUSE
NC score	-0.007920 (rank : 2057)	θ value	0.00665767 (rank : 990)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1063	Shared Neighborhood Hits	203
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

ZN687_HUMAN
NC score	-0.008131 (rank : 2058)	θ value	0.279714 (rank : 1200)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1244	Shared Neighborhood Hits	265
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

DUX4_HUMAN
NC score	-0.008556 (rank : 2059)	θ value	8.99809 (rank : 1895)
Query Neighborhood Hits	1959	Target Neighborhood Hits	403	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UBX2	Gene names	DUX4, DUX10
Domain Architecture	No domain graphic available
Description	Double homeobox protein 4 (Double homeobox protein 10) (Double homeobox protein 4/10).

ERR1_HUMAN
NC score	-0.008713 (rank : 2060)	θ value	6.88961 (rank : 1817)
Query Neighborhood Hits	1959	Target Neighborhood Hits	157	Shared Neighborhood Hits	37
SwissProt Accessions	P11474, Q14514	Gene names	ESRRA, ERR1, ESRL1, NR3B1
Domain Architecture
Description	Steroid hormone receptor ERR1 (Estrogen-related receptor, alpha) (ERR- alpha) (Estrogen receptor-like 1).

2DMB_MOUSE
NC score	-0.009097 (rank : 2061)	θ value	5.27518 (rank : 1707)
Query Neighborhood Hits	1959	Target Neighborhood Hits	214	Shared Neighborhood Hits	17
SwissProt Accessions	P35737	Gene names	H2-DMb1, H-2Mb1, Mb
Domain Architecture
Description	Class II histocompatibility antigen, M beta 1 chain precursor (H2-M beta 1 chain).

NR4A1_HUMAN
NC score	-0.009337 (rank : 2062)	θ value	6.88961 (rank : 1835)
Query Neighborhood Hits	1959	Target Neighborhood Hits	133	Shared Neighborhood Hits	21
SwissProt Accessions	P22736	Gene names	NR4A1, GFRP1, HMR, NAK1
Domain Architecture
Description	Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR) (Early response protein NAK1) (TR3 orphan receptor) (ST-59).

PCD15_MOUSE
NC score	-0.009499 (rank : 2063)	θ value	8.99809 (rank : 1926)
Query Neighborhood Hits	1959	Target Neighborhood Hits	262	Shared Neighborhood Hits	75
SwissProt Accessions	Q99PJ1	Gene names	Pcdh15
Domain Architecture
Description	Protocadherin-15 precursor.

HGFA_HUMAN
NC score	-0.009804 (rank : 2064)	θ value	1.81305 (rank : 1490)
Query Neighborhood Hits	1959	Target Neighborhood Hits	436	Shared Neighborhood Hits	41
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

TITF1_HUMAN
NC score	-0.009985 (rank : 2065)	θ value	4.03905 (rank : 1699)
Query Neighborhood Hits	1959	Target Neighborhood Hits	332	Shared Neighborhood Hits	29
SwissProt Accessions	P43699, O14954, O14955, Q9BRJ8	Gene names	TITF1, NKX2-1, NKX2A, TTF1
Domain Architecture
Description	Thyroid transcription factor 1 (Thyroid nuclear factor 1) (TTF-1) (Homeobox protein Nkx-2.1) (Homeobox protein NK-2 homolog A).

HXD9_HUMAN
NC score	-0.010615 (rank : 2066)	θ value	0.813845 (rank : 1331)
Query Neighborhood Hits	1959	Target Neighborhood Hits	352	Shared Neighborhood Hits	32
SwissProt Accessions	P28356	Gene names	HOXD9, HOX4C
Domain Architecture
Description	Homeobox protein Hox-D9 (Hox-4C) (Hox-5.2).

NR1H3_HUMAN
NC score	-0.010797 (rank : 2067)	θ value	8.99809 (rank : 1924)
Query Neighborhood Hits	1959	Target Neighborhood Hits	104	Shared Neighborhood Hits	4
SwissProt Accessions	Q13133, Q96H87	Gene names	NR1H3, LXRA
Domain Architecture
Description	Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear orphan receptor LXR-alpha).

HXB4_HUMAN
NC score	-0.010864 (rank : 2068)	θ value	0.365318 (rank : 1215)
Query Neighborhood Hits	1959	Target Neighborhood Hits	376	Shared Neighborhood Hits	59
SwissProt Accessions	P17483, Q9NTA0	Gene names	HOXB4, HOX2F
Domain Architecture
Description	Homeobox protein Hox-B4 (Hox-2F) (Hox-2.6).

HXB3_MOUSE
NC score	-0.010936 (rank : 2069)	θ value	1.38821 (rank : 1439)
Query Neighborhood Hits	1959	Target Neighborhood Hits	493	Shared Neighborhood Hits	82
SwissProt Accessions	P09026, P10285, Q4PJ06, Q61680	Gene names	Hoxb3, Hox-2.7, Hoxb-3
Domain Architecture
Description	Homeobox protein Hox-B3 (Hox-2.7) (Homeobox protein MH-23).

HB2A_MOUSE
NC score	-0.011000 (rank : 2070)	θ value	1.38821 (rank : 1435)
Query Neighborhood Hits	1959	Target Neighborhood Hits	203	Shared Neighborhood Hits	10
SwissProt Accessions	P14483	Gene names	H2-Ab1, H2-iabeta
Domain Architecture
Description	H-2 class II histocompatibility antigen, A beta chain precursor.

PCDH8_HUMAN
NC score	-0.011172 (rank : 2071)	θ value	4.03905 (rank : 1675)
Query Neighborhood Hits	1959	Target Neighborhood Hits	164	Shared Neighborhood Hits	14
SwissProt Accessions	O95206, Q8IYE9, Q96SF1	Gene names	PCDH8
Domain Architecture
Description	Protocadherin-8 precursor (Arcadlin).

CELR3_HUMAN
NC score	-0.011198 (rank : 2072)	θ value	6.88961 (rank : 1800)
Query Neighborhood Hits	1959	Target Neighborhood Hits	680	Shared Neighborhood Hits	83
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

HXA4_MOUSE
NC score	-0.012036 (rank : 2073)	θ value	6.88961 (rank : 1825)
Query Neighborhood Hits	1959	Target Neighborhood Hits	379	Shared Neighborhood Hits	54
SwissProt Accessions	P06798, Q61684, Q64388, Q8BPE6	Gene names	Hoxa4, Hox-1.4, Hoxa-4
Domain Architecture
Description	Homeobox protein Hox-A4 (Hox-1.4) (Homeobox protein MH-3).

ZEP2_MOUSE
NC score	-0.012287 (rank : 2074)	θ value	1.06291 (rank : 1418)
Query Neighborhood Hits	1959	Target Neighborhood Hits	964	Shared Neighborhood Hits	160
SwissProt Accessions	Q3UHF7, O55140, Q3UVD4, Q3UVH5	Gene names	Hivep2, Mibp1
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 homolog (Myc intron-binding protein 1) (MIBP-1).

ALX4_HUMAN
NC score	-0.012483 (rank : 2075)	θ value	0.813845 (rank : 1312)
Query Neighborhood Hits	1959	Target Neighborhood Hits	394	Shared Neighborhood Hits	49
SwissProt Accessions	Q9H161, Q96JN7, Q9H198, Q9HAY9	Gene names	ALX4, KIAA1788
Domain Architecture
Description	Homeobox protein aristaless-like 4.

HMX2_MOUSE
NC score	-0.013385 (rank : 2076)	θ value	2.36792 (rank : 1537)
Query Neighborhood Hits	1959	Target Neighborhood Hits	354	Shared Neighborhood Hits	31
SwissProt Accessions	P43687, Q8R1Q2	Gene names	Hmx2, Nkx-5.2, Nkx5-2
Domain Architecture
Description	Homeobox protein HMX2 (Homeobox protein Nkx-5.2).

PLRG1_HUMAN
NC score	-0.013442 (rank : 2077)	θ value	4.03905 (rank : 1681)
Query Neighborhood Hits	1959	Target Neighborhood Hits	318	Shared Neighborhood Hits	18
SwissProt Accessions	O43660, Q8WUD8	Gene names	PLRG1
Domain Architecture
Description	Pleiotropic regulator 1.

ZEP2_HUMAN
NC score	-0.013454 (rank : 2078)	θ value	1.06291 (rank : 1417)
Query Neighborhood Hits	1959	Target Neighborhood Hits	937	Shared Neighborhood Hits	139
SwissProt Accessions	P31629, Q02646, Q5THT5, Q9NS05	Gene names	HIVEP2
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 (HIV- EP2) (MHC-binding protein 2) (MBP-2).

PLRG1_MOUSE
NC score	-0.013633 (rank : 2079)	θ value	2.36792 (rank : 1556)
Query Neighborhood Hits	1959	Target Neighborhood Hits	308	Shared Neighborhood Hits	12
SwissProt Accessions	Q922V4, O55039	Gene names	Plrg1
Domain Architecture
Description	Pleiotropic regulator 1.

ALX3_MOUSE
NC score	-0.013762 (rank : 2080)	θ value	5.27518 (rank : 1712)
Query Neighborhood Hits	1959	Target Neighborhood Hits	386	Shared Neighborhood Hits	42
SwissProt Accessions	O70137	Gene names	Alx3
Domain Architecture
Description	Homeobox protein aristaless-like 3 (Proline-rich transcription factor ALX3).

ATBF1_HUMAN
NC score	-0.013764 (rank : 2081)	θ value	2.36792 (rank : 1522)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1547	Shared Neighborhood Hits	250
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

CDX4_MOUSE
NC score	-0.013796 (rank : 2082)	θ value	4.03905 (rank : 1643)
Query Neighborhood Hits	1959	Target Neighborhood Hits	378	Shared Neighborhood Hits	47
SwissProt Accessions	Q07424	Gene names	Cdx4, Cdx-4
Domain Architecture
Description	Homeobox protein CDX-4 (Caudal-type homeobox protein 4).

NETR_MOUSE
NC score	-0.014331 (rank : 2083)	θ value	5.27518 (rank : 1768)
Query Neighborhood Hits	1959	Target Neighborhood Hits	216	Shared Neighborhood Hits	14
SwissProt Accessions	O08762	Gene names	Prss12, Bssp3
Domain Architecture
Description	Neurotrypsin precursor (EC 3.4.21.-) (Motopsin) (Brain-specific serine protease 3) (BSSP-3).

TRY3_HUMAN
NC score	-0.014399 (rank : 2084)	θ value	8.99809 (rank : 1948)
Query Neighborhood Hits	1959	Target Neighborhood Hits	178	Shared Neighborhood Hits	7
SwissProt Accessions	P35030, P15951, Q15665, Q9UQV3	Gene names	PRSS3, PRSS4, TRY3, TRY4
Domain Architecture
Description	Trypsin-3 precursor (EC 3.4.21.4) (Trypsin III) (Brain trypsinogen) (Mesotrypsinogen) (Trypsin IV).

VAX1_HUMAN
NC score	-0.014657 (rank : 2085)	θ value	8.99809 (rank : 1952)
Query Neighborhood Hits	1959	Target Neighborhood Hits	355	Shared Neighborhood Hits	37
SwissProt Accessions	Q5SQQ9, Q6ZSX0	Gene names	VAX1
Domain Architecture	No domain graphic available
Description	Ventral anterior homeobox 1.

VAX1_MOUSE
NC score	-0.014983 (rank : 2086)	θ value	6.88961 (rank : 1858)
Query Neighborhood Hits	1959	Target Neighborhood Hits	351	Shared Neighborhood Hits	35
SwissProt Accessions	Q2NKI2, O88880	Gene names	Vax1
Domain Architecture	No domain graphic available
Description	Ventral anterior homeobox 1.

SALL3_HUMAN
NC score	-0.015076 (rank : 2087)	θ value	0.365318 (rank : 1235)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1066	Shared Neighborhood Hits	200
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

ZN516_MOUSE
NC score	-0.015746 (rank : 2088)	θ value	6.88961 (rank : 1863)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1197	Shared Neighborhood Hits	250
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

ZN687_MOUSE
NC score	-0.016349 (rank : 2089)	θ value	3.0926 (rank : 1631)
Query Neighborhood Hits	1959	Target Neighborhood Hits	913	Shared Neighborhood Hits	145
SwissProt Accessions	Q9D2D7, Q6PAP3, Q6ZPQ9	Gene names	Znf687, Kiaa1441, Zfp687
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

ZN438_HUMAN
NC score	-0.018158 (rank : 2090)	θ value	8.99809 (rank : 1958)
Query Neighborhood Hits	1959	Target Neighborhood Hits	906	Shared Neighborhood Hits	161
SwissProt Accessions	Q7Z4V0, Q5T426, Q658Q4, Q6ZN65	Gene names	ZNF438
Domain Architecture	No domain graphic available
Description	Zinc finger protein 438.

ZN447_HUMAN
NC score	-0.018733 (rank : 2091)	θ value	1.38821 (rank : 1465)
Query Neighborhood Hits	1959	Target Neighborhood Hits	899	Shared Neighborhood Hits	129
SwissProt Accessions	Q8TBC5, Q9BRK7, Q9H9A0	Gene names	ZNF447
Domain Architecture	No domain graphic available
Description	Zinc finger protein 447.

KLF17_HUMAN
NC score	-0.018741 (rank : 2092)	θ value	0.0961366 (rank : 1108)
Query Neighborhood Hits	1959	Target Neighborhood Hits	882	Shared Neighborhood Hits	148
SwissProt Accessions	Q5JT82, Q86VQ7, Q8N805	Gene names	KLF17, ZNF393
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 17 (Zinc finger protein 393).

ZN219_HUMAN
NC score	-0.019401 (rank : 2093)	θ value	1.38821 (rank : 1464)
Query Neighborhood Hits	1959	Target Neighborhood Hits	876	Shared Neighborhood Hits	137
SwissProt Accessions	Q9P2Y4, Q8IYC1, Q9BW28	Gene names	ZNF219
Domain Architecture	No domain graphic available
Description	Zinc finger protein 219.

GLIS3_MOUSE
NC score	-0.020485 (rank : 2094)	θ value	1.06291 (rank : 1379)
Query Neighborhood Hits	1959	Target Neighborhood Hits	861	Shared Neighborhood Hits	134
SwissProt Accessions	Q6XP49, Q8BI60	Gene names	Glis3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS3 (GLI-similar 3).

GLI2_HUMAN
NC score	-0.022172 (rank : 2095)	θ value	8.99809 (rank : 1901)
Query Neighborhood Hits	1959	Target Neighborhood Hits	971	Shared Neighborhood Hits	159
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

MTR1L_HUMAN
NC score	-0.023201 (rank : 2096)	θ value	3.0926 (rank : 1604)
Query Neighborhood Hits	1959	Target Neighborhood Hits	1180	Shared Neighborhood Hits	149
SwissProt Accessions	Q13585	Gene names	GPR50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).

KLF12_HUMAN
NC score	-0.023533 (rank : 2097)	θ value	0.279714 (rank : 1184)
Query Neighborhood Hits	1959	Target Neighborhood Hits	717	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y4X4, Q5VZM7, Q9UHZ0	Gene names	KLF12, AP2REP
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 12 (Transcriptional repressor AP-2rep).

ZBTB3_HUMAN
NC score	-0.023548 (rank : 2098)	θ value	8.99809 (rank : 1956)
Query Neighborhood Hits	1959	Target Neighborhood Hits	910	Shared Neighborhood Hits	113
SwissProt Accessions	Q9H5J0	Gene names	ZBTB3
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 3.

ZN335_HUMAN
NC score	-0.023699 (rank : 2099)	θ value	0.47712 (rank : 1281)
Query Neighborhood Hits	1959	Target Neighborhood Hits	973	Shared Neighborhood Hits	127
SwissProt Accessions	Q9H4Z2, Q9H684	Gene names	ZNF335
Domain Architecture	No domain graphic available
Description	Zinc finger protein 335.

KLF12_MOUSE
NC score	-0.024218 (rank : 2100)	θ value	3.0926 (rank : 1599)
Query Neighborhood Hits	1959	Target Neighborhood Hits	721	Shared Neighborhood Hits	60
SwissProt Accessions	O35738	Gene names	Klf12, Ap2rep
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 12 (Transcriptional repressor AP-2rep).

GLIS1_MOUSE
NC score	-0.024486 (rank : 2101)	θ value	1.06291 (rank : 1378)
Query Neighborhood Hits	1959	Target Neighborhood Hits	751	Shared Neighborhood Hits	74
SwissProt Accessions	Q8K1M4, Q6NZF6, Q8R4Z3	Gene names	Glis1, Gli5
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS1 (GLI-similar 1) (Gli homologous protein 1) (GliH1).

ZN688_HUMAN
NC score	-0.024604 (rank : 2102)	θ value	4.03905 (rank : 1705)
Query Neighborhood Hits	1959	Target Neighborhood Hits	873	Shared Neighborhood Hits	127
SwissProt Accessions	Q8WV14, O75701, Q8IW91, Q96MN0	Gene names	ZNF688
Domain Architecture	No domain graphic available
Description	Zinc finger protein 688.

KLF13_HUMAN
NC score	-0.024948 (rank : 2103)	θ value	3.0926 (rank : 1600)
Query Neighborhood Hits	1959	Target Neighborhood Hits	739	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Y2Y9, Q9Y356	Gene names	KLF13, BTEB3, NSLP1
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 13 (Transcription factor BTEB3) (Basic transcription element-binding protein 3) (BTE-binding protein 3) (RANTES factor of late activated T-lymphocytes 1) (RFLAT-1) (Transcription factor NSLP1) (Novel Sp1-like zinc finger transcription factor 1).

EGR2_MOUSE
NC score	-0.025008 (rank : 2104)	θ value	5.27518 (rank : 1735)
Query Neighborhood Hits	1959	Target Neighborhood Hits	745	Shared Neighborhood Hits	71
SwissProt Accessions	P08152	Gene names	Egr2, Egr-2, Krox-20, Zfp-25
Domain Architecture	No domain graphic available
Description	Early growth response protein 2 (EGR-2) (Krox-20 protein).

ZN692_MOUSE
NC score	-0.025147 (rank : 2105)	θ value	0.21417 (rank : 1174)
Query Neighborhood Hits	1959	Target Neighborhood Hits	751	Shared Neighborhood Hits	61
SwissProt Accessions	Q3U381	Gene names	Znf692, Zfp692
Domain Architecture	No domain graphic available
Description	Zinc finger protein 692.

MTF1_HUMAN
NC score	-0.025184 (rank : 2106)	θ value	0.62314 (rank : 1300)
Query Neighborhood Hits	1959	Target Neighborhood Hits	814	Shared Neighborhood Hits	99
SwissProt Accessions	Q14872, Q96CB1	Gene names	MTF1
Domain Architecture	No domain graphic available
Description	Metal-regulatory transcription factor 1 (Transcription factor MTF-1) (MRE-binding transcription factor).

KLF17_MOUSE
NC score	-0.025682 (rank : 2107)	θ value	2.36792 (rank : 1545)
Query Neighborhood Hits	1959	Target Neighborhood Hits	684	Shared Neighborhood Hits	48
SwissProt Accessions	Q8CFA7, Q3UT30, Q6P233, Q9D351	Gene names	Klf17, Gzf, Zfp393, Znf393
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 17 (Zinc finger protein 393) (Germ cell-specific zinc finger protein).

ZBT45_HUMAN
NC score	-0.025816 (rank : 2108)	θ value	8.99809 (rank : 1955)
Query Neighborhood Hits	1959	Target Neighborhood Hits	901	Shared Neighborhood Hits	110
SwissProt Accessions	Q96K62	Gene names	ZBTB45, ZNF499
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 45 (Zinc finger protein 499).

BCL6_HUMAN
NC score	-0.026003 (rank : 2109)	θ value	8.99809 (rank : 1870)
Query Neighborhood Hits	1959	Target Neighborhood Hits	922	Shared Neighborhood Hits	109
SwissProt Accessions	P41182	Gene names	BCL6, BCL5, LAZ3, ZBTB27, ZNF51
Domain Architecture
Description	B-cell lymphoma 6 protein (BCL-6) (Zinc finger protein 51) (LAZ-3 protein) (BCL-5) (Zinc finger and BTB domain-containing protein 27).

ZN628_HUMAN
NC score	-0.026606 (rank : 2110)	θ value	5.27518 (rank : 1792)
Query Neighborhood Hits	1959	Target Neighborhood Hits	814	Shared Neighborhood Hits	80
SwissProt Accessions	Q5EBL2, Q86X34	Gene names	ZNF628
Domain Architecture	No domain graphic available
Description	Zinc finger protein 628.

EVI1_MOUSE
NC score	-0.026842 (rank : 2111)	θ value	5.27518 (rank : 1737)
Query Neighborhood Hits	1959	Target Neighborhood Hits	826	Shared Neighborhood Hits	70
SwissProt Accessions	P14404	Gene names	Evi1, Evi-1
Domain Architecture	No domain graphic available
Description	Ecotropic virus integration 1 site protein.

HIC1_HUMAN
NC score	-0.026842 (rank : 2112)	θ value	1.38821 (rank : 1438)
Query Neighborhood Hits	1959	Target Neighborhood Hits	838	Shared Neighborhood Hits	77
SwissProt Accessions	Q14526	Gene names	HIC1, ZBTB29
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1) (Zinc finger and BTB domain-containing protein 29).

ZFP38_HUMAN
NC score	-0.027356 (rank : 2113)	θ value	3.0926 (rank : 1630)
Query Neighborhood Hits	1959	Target Neighborhood Hits	766	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y5A6, Q9H0B5	Gene names	ZNF38, ZFP38, ZSCAN21
Domain Architecture
Description	Zinc finger protein 38 homolog (Zfp-38) (Zinc finger and SCAN domain- containing protein 21) (NY-REN-21 antigen).

ZN268_HUMAN
NC score	-0.027417 (rank : 2114)	θ value	1.81305 (rank : 1517)
Query Neighborhood Hits	1959	Target Neighborhood Hits	753	Shared Neighborhood Hits	47
SwissProt Accessions	Q14587, Q96RH4, Q9BZJ9	Gene names	ZNF268
Domain Architecture
Description	Zinc finger protein 268 (Zinc finger protein HZF3).

ZN524_HUMAN
NC score	-0.027452 (rank : 2115)	θ value	5.27518 (rank : 1791)
Query Neighborhood Hits	1959	Target Neighborhood Hits	707	Shared Neighborhood Hits	45
SwissProt Accessions	Q96C55, Q6NW31, Q96IL7	Gene names	ZNF524
Domain Architecture	No domain graphic available
Description	Zinc finger protein 524.

GLI4_HUMAN
NC score	-0.027545 (rank : 2116)	θ value	1.81305 (rank : 1489)
Query Neighborhood Hits	1959	Target Neighborhood Hits	735	Shared Neighborhood Hits	48
SwissProt Accessions	P10075, Q96CK9	Gene names	GLI4, HKR4
Domain Architecture
Description	Zinc finger protein GLI4 (Krueppel-related zinc finger protein 4) (Protein HKR4).

ZFP13_MOUSE
NC score	-0.027619 (rank : 2117)	θ value	6.88961 (rank : 1860)
Query Neighborhood Hits	1959	Target Neighborhood Hits	771	Shared Neighborhood Hits	66
SwissProt Accessions	P10754, Q80WS0, Q8CDD0	Gene names	Zfp13, Krox-8, Zfp-13
Domain Architecture	No domain graphic available
Description	Zinc finger protein 13 (Zfp-13) (Krox-8 protein).

ZN295_HUMAN
NC score	-0.027706 (rank : 2118)	θ value	6.88961 (rank : 1861)
Query Neighborhood Hits	1959	Target Neighborhood Hits	847	Shared Neighborhood Hits	59
SwissProt Accessions	Q9ULJ3, Q6P4R0	Gene names	ZNF295, KIAA1227, ZBTB21
Domain Architecture
Description	Zinc finger protein 295 (Zinc finger and BTB domain-containing protein 21).

NPFF1_HUMAN
NC score	-0.030032 (rank : 2119)	θ value	2.36792 (rank : 1550)
Query Neighborhood Hits	1959	Target Neighborhood Hits	858	Shared Neighborhood Hits	5
SwissProt Accessions	Q9GZQ6, Q8NGR0, Q96RN3	Gene names	NPFFR1, GPR147, NPFF1
Domain Architecture
Description	Neuropeptide FF receptor 1 (G-protein coupled receptor 147) (RFamide- related peptide receptor OT7T022).