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Network neighborhood for query Sequence : SOX5_HUMAN

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SOX5_HUMAN
SwissProt Accessions	P35711, Q86UK8, Q8J017, Q8J018, Q8J019, Q8J020, Q8N1D9, Q8N7E0, Q8TEA4	Gene names	SOX5
Domain Architecture
Description	Transcription factor SOX-5.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SOX5_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	219	Target Neighborhood Hits	219	Shared Neighborhood Hits	219
SwissProt Accessions	P35711, Q86UK8, Q8J017, Q8J018, Q8J019, Q8J020, Q8N1D9, Q8N7E0, Q8TEA4	Gene names	SOX5
Domain Architecture
Description	Transcription factor SOX-5.

SOX5_MOUSE
θ value	0 (rank : 2)	NC score	0.996992 (rank : 2)
Query Neighborhood Hits	219	Target Neighborhood Hits	196	Shared Neighborhood Hits	183
SwissProt Accessions	P35710, O88184, O89018	Gene names	Sox5, Sox-5
Domain Architecture
Description	Transcription factor SOX-5.

SOX6_HUMAN
θ value	0 (rank : 3)	NC score	0.966185 (rank : 3)
Query Neighborhood Hits	219	Target Neighborhood Hits	332	Shared Neighborhood Hits	138
SwissProt Accessions	P35712, Q9BXQ3, Q9BXQ4, Q9BXQ5, Q9H0I8	Gene names	SOX6
Domain Architecture
Description	Transcription factor SOX-6.

SOX6_MOUSE
θ value	0 (rank : 4)	NC score	0.964328 (rank : 4)
Query Neighborhood Hits	219	Target Neighborhood Hits	341	Shared Neighborhood Hits	139
SwissProt Accessions	P40645, Q62250, Q9QWS5	Gene names	Sox6, Sox-6
Domain Architecture
Description	Transcription factor SOX-6 (SOX-LZ).

SOX13_HUMAN
θ value	4.98072e-83 (rank : 5)	NC score	0.890351 (rank : 5)
Query Neighborhood Hits	219	Target Neighborhood Hits	464	Shared Neighborhood Hits	114
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

SOX13_MOUSE
θ value	1.89707e-74 (rank : 6)	NC score	0.886154 (rank : 6)
Query Neighborhood Hits	219	Target Neighborhood Hits	495	Shared Neighborhood Hits	113
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

SOX7_MOUSE
θ value	2.35151e-24 (rank : 7)	NC score	0.853273 (rank : 14)
Query Neighborhood Hits	219	Target Neighborhood Hits	105	Shared Neighborhood Hits	83
SwissProt Accessions	P40646, Q9R1T6	Gene names	Sox7, Sox-7
Domain Architecture
Description	Transcription factor SOX-7 (mSOX7).

SOX7_HUMAN
θ value	6.84181e-24 (rank : 8)	NC score	0.846493 (rank : 16)
Query Neighborhood Hits	219	Target Neighborhood Hits	140	Shared Neighborhood Hits	80
SwissProt Accessions	Q9BT81	Gene names	SOX7
Domain Architecture
Description	Transcription factor SOX-7.

SOX18_MOUSE
θ value	3.75424e-22 (rank : 9)	NC score	0.855835 (rank : 11)
Query Neighborhood Hits	219	Target Neighborhood Hits	105	Shared Neighborhood Hits	75
SwissProt Accessions	P43680, Q9EQ73	Gene names	Sox18, Sox-18
Domain Architecture
Description	Transcription factor SOX-18.

SOX9_HUMAN
θ value	6.40375e-22 (rank : 10)	NC score	0.815461 (rank : 38)
Query Neighborhood Hits	219	Target Neighborhood Hits	210	Shared Neighborhood Hits	90
SwissProt Accessions	P48436	Gene names	SOX9
Domain Architecture
Description	Transcription factor SOX-9.

SOX9_MOUSE
θ value	6.40375e-22 (rank : 11)	NC score	0.816325 (rank : 37)
Query Neighborhood Hits	219	Target Neighborhood Hits	188	Shared Neighborhood Hits	85
SwissProt Accessions	Q04887, Q8C7L2, Q91ZK2, Q99KQ0	Gene names	Sox9, Sox-9
Domain Architecture
Description	Transcription factor SOX-9.

SOX4_HUMAN
θ value	8.36355e-22 (rank : 12)	NC score	0.856874 (rank : 10)
Query Neighborhood Hits	219	Target Neighborhood Hits	111	Shared Neighborhood Hits	77
SwissProt Accessions	Q06945	Gene names	SOX4
Domain Architecture
Description	Transcription factor SOX-4.

SOX4_MOUSE
θ value	1.42661e-21 (rank : 13)	NC score	0.854807 (rank : 13)
Query Neighborhood Hits	219	Target Neighborhood Hits	108	Shared Neighborhood Hits	77
SwissProt Accessions	Q06831	Gene names	Sox4, Sox-4
Domain Architecture
Description	Transcription factor SOX-4.

SOX10_HUMAN
θ value	5.42112e-21 (rank : 14)	NC score	0.817981 (rank : 36)
Query Neighborhood Hits	219	Target Neighborhood Hits	122	Shared Neighborhood Hits	72
SwissProt Accessions	P56693	Gene names	SOX10
Domain Architecture
Description	Transcription factor SOX-10.

SOX10_MOUSE
θ value	5.42112e-21 (rank : 15)	NC score	0.819031 (rank : 34)
Query Neighborhood Hits	219	Target Neighborhood Hits	110	Shared Neighborhood Hits	72
SwissProt Accessions	Q04888, O08518, O09141, O54856, P70416	Gene names	Sox10, Sox-10, Sox21
Domain Architecture
Description	Transcription factor SOX-10 (SOX-21) (Transcription factor SOX-M).

SRY_MOUSE
θ value	5.42112e-21 (rank : 16)	NC score	0.855606 (rank : 12)
Query Neighborhood Hits	219	Target Neighborhood Hits	139	Shared Neighborhood Hits	87
SwissProt Accessions	Q05738	Gene names	Sry, Tdf, Tdy
Domain Architecture
Description	Sex-determining region Y protein (Testis-determining factor).

SOX17_MOUSE
θ value	9.24701e-21 (rank : 17)	NC score	0.834405 (rank : 24)
Query Neighborhood Hits	219	Target Neighborhood Hits	223	Shared Neighborhood Hits	85
SwissProt Accessions	Q61473, Q61472, Q62248	Gene names	Sox17, Sox-17
Domain Architecture
Description	Transcription factor SOX-17.

SOX8_HUMAN
θ value	9.24701e-21 (rank : 18)	NC score	0.833054 (rank : 27)
Query Neighborhood Hits	219	Target Neighborhood Hits	100	Shared Neighborhood Hits	77
SwissProt Accessions	P57073, Q9NZW2	Gene names	SOX8
Domain Architecture
Description	Transcription factor SOX-8.

SOX8_MOUSE
θ value	9.24701e-21 (rank : 19)	NC score	0.831746 (rank : 28)
Query Neighborhood Hits	219	Target Neighborhood Hits	96	Shared Neighborhood Hits	75
SwissProt Accessions	Q04886	Gene names	Sox8, Sox-8
Domain Architecture
Description	Transcription factor SOX-8.

SOX2_HUMAN
θ value	1.2077e-20 (rank : 20)	NC score	0.835227 (rank : 23)
Query Neighborhood Hits	219	Target Neighborhood Hits	89	Shared Neighborhood Hits	80
SwissProt Accessions	P48431, Q14537	Gene names	SOX2
Domain Architecture
Description	Transcription factor SOX-2.

SOX2_MOUSE
θ value	1.2077e-20 (rank : 21)	NC score	0.835231 (rank : 22)
Query Neighborhood Hits	219	Target Neighborhood Hits	90	Shared Neighborhood Hits	80
SwissProt Accessions	P48432	Gene names	Sox2, Sox-2
Domain Architecture
Description	Transcription factor SOX-2.

SRY_HUMAN
θ value	2.06002e-20 (rank : 22)	NC score	0.864920 (rank : 9)
Query Neighborhood Hits	219	Target Neighborhood Hits	83	Shared Neighborhood Hits	80
SwissProt Accessions	Q05066	Gene names	SRY, TDF
Domain Architecture
Description	Sex-determining region Y protein (Testis-determining factor).

SOX12_HUMAN
θ value	7.82807e-20 (rank : 23)	NC score	0.868186 (rank : 8)
Query Neighborhood Hits	219	Target Neighborhood Hits	111	Shared Neighborhood Hits	74
SwissProt Accessions	O15370, Q9NUD4	Gene names	SOX12, SOX22
Domain Architecture
Description	SOX-12 protein (SOX-22 protein).

SOX12_MOUSE
θ value	7.82807e-20 (rank : 24)	NC score	0.870773 (rank : 7)
Query Neighborhood Hits	219	Target Neighborhood Hits	98	Shared Neighborhood Hits	75
SwissProt Accessions	Q04890, P70417, Q6NXL2	Gene names	Sox12, Sox-12
Domain Architecture	No domain graphic available
Description	SOX-12 protein.

SOX17_HUMAN
θ value	1.74391e-19 (rank : 25)	NC score	0.840760 (rank : 19)
Query Neighborhood Hits	219	Target Neighborhood Hits	108	Shared Neighborhood Hits	80
SwissProt Accessions	Q9H6I2	Gene names	SOX17
Domain Architecture
Description	Transcription factor SOX-17.

SOX18_HUMAN
θ value	9.56915e-18 (rank : 26)	NC score	0.843995 (rank : 18)
Query Neighborhood Hits	219	Target Neighborhood Hits	106	Shared Neighborhood Hits	76
SwissProt Accessions	P35713, Q9NPH8	Gene names	SOX18
Domain Architecture
Description	Transcription factor SOX-18.

SOX14_HUMAN
θ value	1.24977e-17 (rank : 27)	NC score	0.834029 (rank : 26)
Query Neighborhood Hits	219	Target Neighborhood Hits	102	Shared Neighborhood Hits	81
SwissProt Accessions	O95416, Q3KPH7	Gene names	SOX14, SOX28
Domain Architecture
Description	Transcription factor SOX-14.

SOX14_MOUSE
θ value	1.24977e-17 (rank : 28)	NC score	0.834120 (rank : 25)
Query Neighborhood Hits	219	Target Neighborhood Hits	100	Shared Neighborhood Hits	81
SwissProt Accessions	Q04892, Q9JLC9, Q9JLD0, Q9QXU4	Gene names	Sox14, Sox-14
Domain Architecture
Description	Transcription factor SOX-14.

SOX1_HUMAN
θ value	1.80466e-16 (rank : 29)	NC score	0.828023 (rank : 30)
Query Neighborhood Hits	219	Target Neighborhood Hits	90	Shared Neighborhood Hits	80
SwissProt Accessions	O00570	Gene names	SOX1
Domain Architecture
Description	SOX-1 protein.

SOX1_MOUSE
θ value	2.35696e-16 (rank : 30)	NC score	0.826934 (rank : 31)
Query Neighborhood Hits	219	Target Neighborhood Hits	90	Shared Neighborhood Hits	80
SwissProt Accessions	P53783	Gene names	Sox1, Sox-1
Domain Architecture
Description	SOX-1 protein.

SOX11_HUMAN
θ value	3.07829e-16 (rank : 31)	NC score	0.846769 (rank : 15)
Query Neighborhood Hits	219	Target Neighborhood Hits	89	Shared Neighborhood Hits	78
SwissProt Accessions	P35716	Gene names	SOX11
Domain Architecture
Description	Transcription factor SOX-11.

SOX11_MOUSE
θ value	3.07829e-16 (rank : 32)	NC score	0.844175 (rank : 17)
Query Neighborhood Hits	219	Target Neighborhood Hits	96	Shared Neighborhood Hits	79
SwissProt Accessions	Q7M6Y2, O35178, O89036, Q04889, Q80XF0	Gene names	Sox11, Sox-11
Domain Architecture	No domain graphic available
Description	Transcription factor SOX-11.

SOX21_HUMAN
θ value	6.85773e-16 (rank : 33)	NC score	0.835501 (rank : 21)
Query Neighborhood Hits	219	Target Neighborhood Hits	89	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Y651, P35715, Q15504	Gene names	SOX21, SOX25, SOXA
Domain Architecture
Description	Transcription factor SOX-21 (SOX-A).

SOX21_MOUSE
θ value	6.85773e-16 (rank : 34)	NC score	0.835512 (rank : 20)
Query Neighborhood Hits	219	Target Neighborhood Hits	90	Shared Neighborhood Hits	79
SwissProt Accessions	Q811W0, Q8VH35	Gene names	Sox21
Domain Architecture	No domain graphic available
Description	Transcription factor SOX-21.

SOX3_MOUSE
θ value	1.52774e-15 (rank : 35)	NC score	0.821821 (rank : 33)
Query Neighborhood Hits	219	Target Neighborhood Hits	101	Shared Neighborhood Hits	79
SwissProt Accessions	P53784	Gene names	Sox3, Sox-3
Domain Architecture
Description	Transcription factor SOX-3.

SOX3_HUMAN
θ value	1.99529e-15 (rank : 36)	NC score	0.818154 (rank : 35)
Query Neighborhood Hits	219	Target Neighborhood Hits	109	Shared Neighborhood Hits	80
SwissProt Accessions	P41225, P35714, Q9NP49	Gene names	SOX3
Domain Architecture
Description	Transcription factor SOX-3.

SOX15_HUMAN
θ value	6.41864e-14 (rank : 37)	NC score	0.825107 (rank : 32)
Query Neighborhood Hits	219	Target Neighborhood Hits	134	Shared Neighborhood Hits	82
SwissProt Accessions	O60248, P35717, Q9Y6W7	Gene names	SOX15, SOX12, SOX20, SOX26, SOX27
Domain Architecture
Description	SOX-15 protein (SOX-20 protein) (SOX-12 protein).

SOX15_MOUSE
θ value	1.09485e-13 (rank : 38)	NC score	0.829985 (rank : 29)
Query Neighborhood Hits	219	Target Neighborhood Hits	100	Shared Neighborhood Hits	80
SwissProt Accessions	P43267, O70204, P70418, Q62246, Q91V00, Q91V43, Q920T1, Q9JLG2	Gene names	Sox15, Sox-15
Domain Architecture
Description	SOX-15 protein.

SOX30_HUMAN
θ value	1.2105e-12 (rank : 39)	NC score	0.742337 (rank : 40)
Query Neighborhood Hits	219	Target Neighborhood Hits	305	Shared Neighborhood Hits	88
SwissProt Accessions	O94993, O94995, Q8IYX6	Gene names	SOX30
Domain Architecture
Description	Transcription factor SOX-30.

SOX30_MOUSE
θ value	1.2105e-12 (rank : 40)	NC score	0.743365 (rank : 39)
Query Neighborhood Hits	219	Target Neighborhood Hits	374	Shared Neighborhood Hits	95
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

CIC_HUMAN
θ value	2.0648e-12 (rank : 41)	NC score	0.592791 (rank : 46)
Query Neighborhood Hits	219	Target Neighborhood Hits	992	Shared Neighborhood Hits	106
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CIC_MOUSE
θ value	2.0648e-12 (rank : 42)	NC score	0.628672 (rank : 43)
Query Neighborhood Hits	219	Target Neighborhood Hits	742	Shared Neighborhood Hits	99
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

HBP1_MOUSE
θ value	6.21693e-09 (rank : 43)	NC score	0.662432 (rank : 41)
Query Neighborhood Hits	219	Target Neighborhood Hits	86	Shared Neighborhood Hits	77
SwissProt Accessions	Q8R316, Q3V0I4, Q8BUS3, Q8C199	Gene names	Hbp1
Domain Architecture	No domain graphic available
Description	HMG box-containing protein 1 (HMG box transcription factor 1) (High mobility group box transcription factor 1).

LEF1_HUMAN
θ value	1.80886e-08 (rank : 44)	NC score	0.579940 (rank : 49)
Query Neighborhood Hits	219	Target Neighborhood Hits	150	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UJU2, Q9HAZ0	Gene names	LEF1
Domain Architecture
Description	Lymphoid enhancer-binding factor 1 (LEF-1) (T cell-specific transcription factor 1-alpha) (TCF1-alpha).

LEF1_MOUSE
θ value	1.80886e-08 (rank : 45)	NC score	0.578639 (rank : 50)
Query Neighborhood Hits	219	Target Neighborhood Hits	161	Shared Neighborhood Hits	76
SwissProt Accessions	P27782	Gene names	Lef1, Lef-1
Domain Architecture
Description	Lymphoid enhancer-binding factor 1 (LEF-1).

HBP1_HUMAN
θ value	3.08544e-08 (rank : 46)	NC score	0.659501 (rank : 42)
Query Neighborhood Hits	219	Target Neighborhood Hits	89	Shared Neighborhood Hits	76
SwissProt Accessions	O60381, Q8TBM1, Q8TE93, Q96AJ2	Gene names	HBP1
Domain Architecture	No domain graphic available
Description	HMG box-containing protein 1 (HMG box transcription factor 1) (High mobility group box transcription factor 1).

TCF7_HUMAN
θ value	6.87365e-08 (rank : 47)	NC score	0.624591 (rank : 44)
Query Neighborhood Hits	219	Target Neighborhood Hits	186	Shared Neighborhood Hits	73
SwissProt Accessions	P36402, Q9UKI4	Gene names	TCF7, TCF1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

TF7L2_HUMAN
θ value	1.17247e-07 (rank : 48)	NC score	0.574639 (rank : 52)
Query Neighborhood Hits	219	Target Neighborhood Hits	119	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NQB0, O00185, Q9NQB1, Q9NQB2, Q9NQB3, Q9NQB4, Q9NQB5, Q9NQB6, Q9NQB7, Q9ULC2	Gene names	TCF7L2, TCF4
Domain Architecture
Description	Transcription factor 7-like 2 (HMG box transcription factor 4) (T- cell-specific transcription factor 4) (TCF-4) (hTCF-4).

TF7L2_MOUSE
θ value	1.17247e-07 (rank : 49)	NC score	0.578198 (rank : 51)
Query Neighborhood Hits	219	Target Neighborhood Hits	95	Shared Neighborhood Hits	65
SwissProt Accessions	Q924A0, O70574, Q91XP2, Q91XP3, Q91XP4, Q924A1, Q9Z0V3, Q9Z0V4	Gene names	Tcf7l2, Tcf4
Domain Architecture
Description	Transcription factor 7-like 2 (HMG box transcription factor 4) (T- cell-specific transcription factor 4) (TCF-4) (mTCF-4).

TCF7_MOUSE
θ value	1.69304e-06 (rank : 50)	NC score	0.585028 (rank : 48)
Query Neighborhood Hits	219	Target Neighborhood Hits	277	Shared Neighborhood Hits	73
SwissProt Accessions	Q00417	Gene names	Tcf7, Tcf-1, Tcf1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

BBX_HUMAN
θ value	4.92598e-06 (rank : 51)	NC score	0.596206 (rank : 45)
Query Neighborhood Hits	219	Target Neighborhood Hits	167	Shared Neighborhood Hits	84
SwissProt Accessions	Q8WY36, Q2TAJ1, Q7L3J8, Q7LBY8, Q8NDB0, Q8WY35, Q9H0J6	Gene names	BBX, HBP2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

TF7L1_MOUSE
θ value	4.92598e-06 (rank : 52)	NC score	0.558061 (rank : 53)
Query Neighborhood Hits	219	Target Neighborhood Hits	131	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Z1J1, O70450, O70573	Gene names	Tcf7l1, Tcf3
Domain Architecture
Description	Transcription factor 7-like 1 (HMG box transcription factor 3) (TCF-3) (mTCF-3).

TF7L1_HUMAN
θ value	6.43352e-06 (rank : 53)	NC score	0.555020 (rank : 54)
Query Neighborhood Hits	219	Target Neighborhood Hits	129	Shared Neighborhood Hits	73
SwissProt Accessions	Q9HCS4, Q53R97, Q6PD70, Q9NP00	Gene names	TCF7L1, TCF3
Domain Architecture
Description	Transcription factor 7-like 1 (HMG box transcription factor 3) (TCF- 3).

BBX_MOUSE
θ value	1.09739e-05 (rank : 54)	NC score	0.586527 (rank : 47)
Query Neighborhood Hits	219	Target Neighborhood Hits	152	Shared Neighborhood Hits	77
SwissProt Accessions	Q8VBW5, Q3TZK1, Q6NXY8, Q6PEU3, Q8BQJ7, Q8C7E0, Q8CDQ0, Q8CDV1, Q8VI48, Q8VI49, Q8VI50, Q9CS94	Gene names	Bbx, Hbp2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

SSRP1_HUMAN
θ value	5.44631e-05 (rank : 55)	NC score	0.511688 (rank : 58)
Query Neighborhood Hits	219	Target Neighborhood Hits	187	Shared Neighborhood Hits	86
SwissProt Accessions	Q08945, Q5BJG8	Gene names	SSRP1, FACT80
Domain Architecture
Description	FACT complex subunit SSRP1 (Facilitates chromatin transcription complex subunit SSRP1) (FACT 80 kDa subunit) (FACTp80) (Chromatin- specific transcription elongation factor 80 kDa subunit) (Structure- specific recognition protein 1) (hSSRP1) (Recombination signal sequence recognition protein 1) (T160).

HMGB2_HUMAN
θ value	0.000158464 (rank : 56)	NC score	0.494610 (rank : 60)
Query Neighborhood Hits	219	Target Neighborhood Hits	114	Shared Neighborhood Hits	82
SwissProt Accessions	P26583	Gene names	HMGB2, HMG2
Domain Architecture
Description	High mobility group protein B2 (High mobility group protein 2) (HMG- 2).

SSRP1_MOUSE
θ value	0.000158464 (rank : 57)	NC score	0.519071 (rank : 57)
Query Neighborhood Hits	219	Target Neighborhood Hits	193	Shared Neighborhood Hits	92
SwissProt Accessions	Q08943, Q3U9Z2, Q3UJ75, Q4V9U4, Q8CGA6	Gene names	Ssrp1
Domain Architecture
Description	FACT complex subunit SSRP1 (Facilitates chromatin transcription complex subunit SSRP1) (Structure-specific recognition protein 1) (Recombination signal sequence recognition protein 1) (T160).

UBF1_MOUSE
θ value	0.000270298 (rank : 58)	NC score	0.443642 (rank : 66)
Query Neighborhood Hits	219	Target Neighborhood Hits	419	Shared Neighborhood Hits	107
SwissProt Accessions	P25976	Gene names	Ubtf, Tcfubf, Ubf-1, Ubf1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1).

HMGB2_MOUSE
θ value	0.00035302 (rank : 59)	NC score	0.482663 (rank : 62)
Query Neighborhood Hits	219	Target Neighborhood Hits	111	Shared Neighborhood Hits	81
SwissProt Accessions	P30681, Q3UXT1, Q9EQD5	Gene names	Hmgb2, Hmg2
Domain Architecture
Description	High mobility group protein B2 (High mobility group protein 2) (HMG- 2).

HMGB3_HUMAN
θ value	0.00035302 (rank : 60)	NC score	0.528948 (rank : 55)
Query Neighborhood Hits	219	Target Neighborhood Hits	86	Shared Neighborhood Hits	72
SwissProt Accessions	O15347, O95556, Q6NS40	Gene names	HMGB3, HMG2A, HMG4
Domain Architecture
Description	High mobility group protein B3 (High mobility group protein 4) (HMG-4) (High mobility group protein 2a) (HMG-2a).

HMGB3_MOUSE
θ value	0.00035302 (rank : 61)	NC score	0.524786 (rank : 56)
Query Neighborhood Hits	219	Target Neighborhood Hits	88	Shared Neighborhood Hits	73
SwissProt Accessions	O54879	Gene names	Hmgb3, Hmg2a, Hmg4
Domain Architecture
Description	High mobility group protein B3 (High mobility group protein 4) (HMG-4) (High mobility group protein 2a) (HMG-2a).

HM20B_HUMAN
θ value	0.000786445 (rank : 62)	NC score	0.511260 (rank : 59)
Query Neighborhood Hits	219	Target Neighborhood Hits	126	Shared Neighborhood Hits	85
SwissProt Accessions	Q9P0W2, Q6IBP8, Q8NBD5, Q9HD21, Q9Y491, Q9Y4A2	Gene names	HMG20B, BRAF35, HMGX2, SMARCE1R
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related (SMARCE1-related protein) (HMG domain protein HMG20B) (Structural DNA-binding protein BRAF35) (BRCA2- associated factor 35) (Sox-like transcriptional factor).

UBF1_HUMAN
θ value	0.000786445 (rank : 63)	NC score	0.445355 (rank : 65)
Query Neighborhood Hits	219	Target Neighborhood Hits	415	Shared Neighborhood Hits	102
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

HM20B_MOUSE
θ value	0.00102713 (rank : 64)	NC score	0.492872 (rank : 61)
Query Neighborhood Hits	219	Target Neighborhood Hits	122	Shared Neighborhood Hits	87
SwissProt Accessions	Q9Z104, Q9NSF7, Q9NSF8	Gene names	Hmg20b, Braf35, Hmgx2, Smarce1r
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related (SMARCE1-related protein) (HMG domain protein HMG20B) (Structural DNA-binding protein BRAF35) (BRCA2- associated factor 35).

HMGB1_HUMAN
θ value	0.00298849 (rank : 65)	NC score	0.453690 (rank : 63)
Query Neighborhood Hits	219	Target Neighborhood Hits	126	Shared Neighborhood Hits	82
SwissProt Accessions	P09429, Q6IBE1	Gene names	HMGB1, HMG1
Domain Architecture
Description	High mobility group protein B1 (High mobility group protein 1) (HMG- 1).

HMGB1_MOUSE
θ value	0.00298849 (rank : 66)	NC score	0.453374 (rank : 64)
Query Neighborhood Hits	219	Target Neighborhood Hits	123	Shared Neighborhood Hits	81
SwissProt Accessions	P63158, P07155, P27109, P27428	Gene names	Hmgb1, Hmg-1, Hmg1
Domain Architecture	No domain graphic available
Description	High mobility group protein B1 (High mobility group protein 1) (HMG- 1).

HM20A_HUMAN
θ value	0.00869519 (rank : 67)	NC score	0.430850 (rank : 68)
Query Neighborhood Hits	219	Target Neighborhood Hits	343	Shared Neighborhood Hits	118
SwissProt Accessions	Q9NP66, Q53G31, Q9NSF6	Gene names	HMG20A, HMGX1
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (HMG domain-containing protein HMGX1).

HM20A_MOUSE
θ value	0.00869519 (rank : 68)	NC score	0.431199 (rank : 67)
Query Neighborhood Hits	219	Target Neighborhood Hits	348	Shared Neighborhood Hits	117
SwissProt Accessions	Q9DC33, Q3LSF9, Q6NV87, Q8BSK1, Q8C3C1, Q8CAA0, Q9CYG2	Gene names	Hmg20a, Ibraf
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (iBRAF) (Inhibitor of BRAF35) (HMG domain protein HMGX1).

CF060_HUMAN
θ value	0.0148317 (rank : 69)	NC score	0.066426 (rank : 92)
Query Neighborhood Hits	219	Target Neighborhood Hits	1270	Shared Neighborhood Hits	84
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

HIP1_HUMAN
θ value	0.0148317 (rank : 70)	NC score	0.056664 (rank : 109)
Query Neighborhood Hits	219	Target Neighborhood Hits	1016	Shared Neighborhood Hits	78
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

TFEB_HUMAN
θ value	0.0330416 (rank : 71)	NC score	0.043605 (rank : 150)
Query Neighborhood Hits	219	Target Neighborhood Hits	111	Shared Neighborhood Hits	10
SwissProt Accessions	P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8	Gene names	TFEB
Domain Architecture
Description	Transcription factor EB.

GOGA1_HUMAN
θ value	0.0431538 (rank : 72)	NC score	0.069195 (rank : 89)
Query Neighborhood Hits	219	Target Neighborhood Hits	1222	Shared Neighborhood Hits	92
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

MAP4_MOUSE
θ value	0.0431538 (rank : 73)	NC score	0.045011 (rank : 147)
Query Neighborhood Hits	219	Target Neighborhood Hits	409	Shared Neighborhood Hits	23
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

CCD46_MOUSE
θ value	0.0563607 (rank : 74)	NC score	0.063156 (rank : 93)
Query Neighborhood Hits	219	Target Neighborhood Hits	1405	Shared Neighborhood Hits	95
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

CUTL1_MOUSE
θ value	0.0563607 (rank : 75)	NC score	0.077253 (rank : 84)
Query Neighborhood Hits	219	Target Neighborhood Hits	1620	Shared Neighborhood Hits	95
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

TOX_HUMAN
θ value	0.0563607 (rank : 76)	NC score	0.239247 (rank : 79)
Query Neighborhood Hits	219	Target Neighborhood Hits	106	Shared Neighborhood Hits	53
SwissProt Accessions	O94900, Q96AV5	Gene names	TOX, KIAA0808
Domain Architecture	No domain graphic available
Description	Thymus high mobility group box protein TOX.

TOX_MOUSE
θ value	0.0563607 (rank : 77)	NC score	0.239542 (rank : 78)
Query Neighborhood Hits	219	Target Neighborhood Hits	95	Shared Neighborhood Hits	53
SwissProt Accessions	Q66JW3, Q8BKH9, Q8BYQ5, Q8R4H0	Gene names	Tox
Domain Architecture	No domain graphic available
Description	Thymus high mobility group box protein TOX.

CASP_HUMAN
θ value	0.0736092 (rank : 78)	NC score	0.074569 (rank : 85)
Query Neighborhood Hits	219	Target Neighborhood Hits	1131	Shared Neighborhood Hits	87
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CN092_HUMAN
θ value	0.0736092 (rank : 79)	NC score	0.263748 (rank : 74)
Query Neighborhood Hits	219	Target Neighborhood Hits	143	Shared Neighborhood Hits	67
SwissProt Accessions	O94842	Gene names	C14orf92, KIAA0737
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

CN092_MOUSE
θ value	0.0736092 (rank : 80)	NC score	0.256919 (rank : 75)
Query Neighborhood Hits	219	Target Neighborhood Hits	206	Shared Neighborhood Hits	72
SwissProt Accessions	Q8BU11, Q80UI2, Q99PN9, Q9CS16	Gene names
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

CUTL1_HUMAN
θ value	0.0736092 (rank : 81)	NC score	0.071303 (rank : 88)
Query Neighborhood Hits	219	Target Neighborhood Hits	1574	Shared Neighborhood Hits	95
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

HMG1X_HUMAN
θ value	0.0736092 (rank : 82)	NC score	0.407373 (rank : 69)
Query Neighborhood Hits	219	Target Neighborhood Hits	97	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UGV6	Gene names	HMG1L10
Domain Architecture
Description	High mobility group protein 1-like 10 (HMG-1L10).

MAGE1_HUMAN
θ value	0.0736092 (rank : 83)	NC score	0.019782 (rank : 198)
Query Neighborhood Hits	219	Target Neighborhood Hits	1389	Shared Neighborhood Hits	39
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

STK10_HUMAN
θ value	0.0736092 (rank : 84)	NC score	0.022659 (rank : 191)
Query Neighborhood Hits	219	Target Neighborhood Hits	1921	Shared Neighborhood Hits	87
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

MRCKB_HUMAN
θ value	0.0961366 (rank : 85)	NC score	0.025959 (rank : 185)
Query Neighborhood Hits	219	Target Neighborhood Hits	2239	Shared Neighborhood Hits	100
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

SYGP1_HUMAN
θ value	0.0961366 (rank : 86)	NC score	0.041725 (rank : 156)
Query Neighborhood Hits	219	Target Neighborhood Hits	589	Shared Neighborhood Hits	62
SwissProt Accessions	Q96PV0, Q8TCS2, Q9UGE2	Gene names	SYNGAP1, KIAA1938
Domain Architecture
Description	Ras GTPase-activating protein SynGAP (Synaptic Ras-GTPase-activating protein 1) (Synaptic Ras-GAP 1) (Neuronal RasGAP).

CCD46_HUMAN
θ value	0.125558 (rank : 87)	NC score	0.066833 (rank : 91)
Query Neighborhood Hits	219	Target Neighborhood Hits	1430	Shared Neighborhood Hits	99
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

GOGA5_MOUSE
θ value	0.125558 (rank : 88)	NC score	0.058506 (rank : 104)
Query Neighborhood Hits	219	Target Neighborhood Hits	1434	Shared Neighborhood Hits	93
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

STK10_MOUSE
θ value	0.125558 (rank : 89)	NC score	0.023735 (rank : 189)
Query Neighborhood Hits	219	Target Neighborhood Hits	2132	Shared Neighborhood Hits	93
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

BAZ2A_MOUSE
θ value	0.163984 (rank : 90)	NC score	0.026498 (rank : 183)
Query Neighborhood Hits	219	Target Neighborhood Hits	744	Shared Neighborhood Hits	46
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

TFEB_MOUSE
θ value	0.163984 (rank : 91)	NC score	0.041736 (rank : 155)
Query Neighborhood Hits	219	Target Neighborhood Hits	119	Shared Neighborhood Hits	12
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

CASP_MOUSE
θ value	0.21417 (rank : 92)	NC score	0.073734 (rank : 86)
Query Neighborhood Hits	219	Target Neighborhood Hits	1152	Shared Neighborhood Hits	86
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

GOGB1_HUMAN
θ value	0.21417 (rank : 93)	NC score	0.046658 (rank : 139)
Query Neighborhood Hits	219	Target Neighborhood Hits	2297	Shared Neighborhood Hits	104
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

K0555_HUMAN
θ value	0.21417 (rank : 94)	NC score	0.061378 (rank : 99)
Query Neighborhood Hits	219	Target Neighborhood Hits	880	Shared Neighborhood Hits	77
SwissProt Accessions	Q96AA8, O60302	Gene names	KIAA0555
Domain Architecture	No domain graphic available
Description	Protein KIAA0555.

AZI1_MOUSE
θ value	0.279714 (rank : 95)	NC score	0.061787 (rank : 98)
Query Neighborhood Hits	219	Target Neighborhood Hits	990	Shared Neighborhood Hits	81
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

MY18A_HUMAN
θ value	0.279714 (rank : 96)	NC score	0.045792 (rank : 145)
Query Neighborhood Hits	219	Target Neighborhood Hits	1929	Shared Neighborhood Hits	97
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MY18A_MOUSE
θ value	0.279714 (rank : 97)	NC score	0.046626 (rank : 141)
Query Neighborhood Hits	219	Target Neighborhood Hits	1989	Shared Neighborhood Hits	102
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

NIN_MOUSE
θ value	0.279714 (rank : 98)	NC score	0.052770 (rank : 119)
Query Neighborhood Hits	219	Target Neighborhood Hits	1376	Shared Neighborhood Hits	89
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

PB1_HUMAN
θ value	0.279714 (rank : 99)	NC score	0.255312 (rank : 76)
Query Neighborhood Hits	219	Target Neighborhood Hits	261	Shared Neighborhood Hits	85
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

RAI14_MOUSE
θ value	0.279714 (rank : 100)	NC score	0.034359 (rank : 172)
Query Neighborhood Hits	219	Target Neighborhood Hits	1505	Shared Neighborhood Hits	86
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

SMCE1_HUMAN
θ value	0.279714 (rank : 101)	NC score	0.323708 (rank : 71)
Query Neighborhood Hits	219	Target Neighborhood Hits	272	Shared Neighborhood Hits	99
SwissProt Accessions	Q969G3, O43539	Gene names	SMARCE1, BAF57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 (BRG1-associated factor 57).

SMCE1_MOUSE
θ value	0.279714 (rank : 102)	NC score	0.308379 (rank : 72)
Query Neighborhood Hits	219	Target Neighborhood Hits	409	Shared Neighborhood Hits	106
SwissProt Accessions	O54941, Q8BPD9	Gene names	Smarce1, Baf57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator chromatin subfamily E member 1 (BRG1-associated factor 57).

ATX1_MOUSE
θ value	0.365318 (rank : 103)	NC score	0.062913 (rank : 95)
Query Neighborhood Hits	219	Target Neighborhood Hits	264	Shared Neighborhood Hits	18
SwissProt Accessions	P54254	Gene names	Atxn1, Sca1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).

E41L2_MOUSE
θ value	0.365318 (rank : 104)	NC score	0.017234 (rank : 203)
Query Neighborhood Hits	219	Target Neighborhood Hits	459	Shared Neighborhood Hits	35
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

GCX1_HUMAN
θ value	0.365318 (rank : 105)	NC score	0.207339 (rank : 82)
Query Neighborhood Hits	219	Target Neighborhood Hits	132	Shared Neighborhood Hits	55
SwissProt Accessions	Q96NM4, Q5TE33, Q5TE34, Q5TE35, Q96IC9, Q9BQN5	Gene names	GCX1, C20orf100
Domain Architecture
Description	Granulosa cell HMG box protein 1 (GCX-1).

GOGA3_MOUSE
θ value	0.365318 (rank : 106)	NC score	0.050281 (rank : 132)
Query Neighborhood Hits	219	Target Neighborhood Hits	1437	Shared Neighborhood Hits	85
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

HAP1_HUMAN
θ value	0.365318 (rank : 107)	NC score	0.062279 (rank : 96)
Query Neighborhood Hits	219	Target Neighborhood Hits	606	Shared Neighborhood Hits	69
SwissProt Accessions	P54257, O75358, Q9H4G3, Q9HA98, Q9NY90	Gene names	HAP1, HLP1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1) (Neuroan 1).

HGS_HUMAN
θ value	0.365318 (rank : 108)	NC score	0.071999 (rank : 87)
Query Neighborhood Hits	219	Target Neighborhood Hits	517	Shared Neighborhood Hits	46
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

HGS_MOUSE
θ value	0.365318 (rank : 109)	NC score	0.069105 (rank : 90)
Query Neighborhood Hits	219	Target Neighborhood Hits	589	Shared Neighborhood Hits	52
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

IFT81_MOUSE
θ value	0.47712 (rank : 110)	NC score	0.060829 (rank : 100)
Query Neighborhood Hits	219	Target Neighborhood Hits	959	Shared Neighborhood Hits	78
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

PTPRN_MOUSE
θ value	0.47712 (rank : 111)	NC score	0.010759 (rank : 214)
Query Neighborhood Hits	219	Target Neighborhood Hits	240	Shared Neighborhood Hits	8
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

RB6I2_HUMAN
θ value	0.47712 (rank : 112)	NC score	0.059758 (rank : 102)
Query Neighborhood Hits	219	Target Neighborhood Hits	1584	Shared Neighborhood Hits	95
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

HOME2_MOUSE
θ value	0.62314 (rank : 113)	NC score	0.042067 (rank : 153)
Query Neighborhood Hits	219	Target Neighborhood Hits	882	Shared Neighborhood Hits	76
SwissProt Accessions	Q9QWW1, O89025, Q9Z0E4	Gene names	Homer2, Vesl2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up- regulated during seizure and LTP 2) (Vesl-2).

RB6I2_MOUSE
θ value	0.62314 (rank : 114)	NC score	0.062178 (rank : 97)
Query Neighborhood Hits	219	Target Neighborhood Hits	1433	Shared Neighborhood Hits	94
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

ACINU_MOUSE
θ value	0.813845 (rank : 115)	NC score	0.043048 (rank : 151)
Query Neighborhood Hits	219	Target Neighborhood Hits	712	Shared Neighborhood Hits	72
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

AF9_HUMAN
θ value	0.813845 (rank : 116)	NC score	0.020445 (rank : 197)
Query Neighborhood Hits	219	Target Neighborhood Hits	202	Shared Neighborhood Hits	11
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

CCD11_HUMAN
θ value	0.813845 (rank : 117)	NC score	0.077984 (rank : 83)
Query Neighborhood Hits	219	Target Neighborhood Hits	822	Shared Neighborhood Hits	81
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CP250_HUMAN
θ value	0.813845 (rank : 118)	NC score	0.054925 (rank : 111)
Query Neighborhood Hits	219	Target Neighborhood Hits	1805	Shared Neighborhood Hits	105
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

MLL3_HUMAN
θ value	0.813845 (rank : 119)	NC score	0.037808 (rank : 164)
Query Neighborhood Hits	219	Target Neighborhood Hits	1644	Shared Neighborhood Hits	82
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

BPAEA_MOUSE
θ value	1.06291 (rank : 120)	NC score	0.047088 (rank : 138)
Query Neighborhood Hits	219	Target Neighborhood Hits	1480	Shared Neighborhood Hits	91
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CENPF_HUMAN
θ value	1.06291 (rank : 121)	NC score	0.050699 (rank : 131)
Query Neighborhood Hits	219	Target Neighborhood Hits	1932	Shared Neighborhood Hits	98
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CEP57_HUMAN
θ value	1.06291 (rank : 122)	NC score	0.052490 (rank : 121)
Query Neighborhood Hits	219	Target Neighborhood Hits	576	Shared Neighborhood Hits	70
SwissProt Accessions	Q86XR8, Q14704, Q8IXP0, Q9BVF9	Gene names	CEP57, KIAA0092, TSP57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin) (FGF2-interacting protein).

GOGA4_HUMAN
θ value	1.06291 (rank : 123)	NC score	0.051637 (rank : 125)
Query Neighborhood Hits	219	Target Neighborhood Hits	2034	Shared Neighborhood Hits	103
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

JHD2C_MOUSE
θ value	1.06291 (rank : 124)	NC score	0.020843 (rank : 196)
Query Neighborhood Hits	219	Target Neighborhood Hits	297	Shared Neighborhood Hits	12
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

LIPS_MOUSE
θ value	1.06291 (rank : 125)	NC score	0.031246 (rank : 177)
Query Neighborhood Hits	219	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	P54310, P97866, Q3TE34, Q6GU16	Gene names	Lipe
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

SPEG_HUMAN
θ value	1.06291 (rank : 126)	NC score	0.008614 (rank : 221)
Query Neighborhood Hits	219	Target Neighborhood Hits	1762	Shared Neighborhood Hits	34
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

CE290_HUMAN
θ value	1.38821 (rank : 127)	NC score	0.054538 (rank : 114)
Query Neighborhood Hits	219	Target Neighborhood Hits	1553	Shared Neighborhood Hits	95
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

GOGA5_HUMAN
θ value	1.38821 (rank : 128)	NC score	0.060276 (rank : 101)
Query Neighborhood Hits	219	Target Neighborhood Hits	1168	Shared Neighborhood Hits	86
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

LMNB2_HUMAN
θ value	1.38821 (rank : 129)	NC score	0.034364 (rank : 170)
Query Neighborhood Hits	219	Target Neighborhood Hits	723	Shared Neighborhood Hits	73
SwissProt Accessions	Q03252, O75292, Q14734, Q96DF6	Gene names	LMNB2, LMN2
Domain Architecture
Description	Lamin-B2.

PRRT3_HUMAN
θ value	1.38821 (rank : 130)	NC score	0.028897 (rank : 181)
Query Neighborhood Hits	219	Target Neighborhood Hits	998	Shared Neighborhood Hits	46
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

TFAM_MOUSE
θ value	1.38821 (rank : 131)	NC score	0.304168 (rank : 73)
Query Neighborhood Hits	219	Target Neighborhood Hits	93	Shared Neighborhood Hits	78
SwissProt Accessions	P40630, P97894, P97906, Q543I8, Q9DBM9	Gene names	Tfam, Hmgts
Domain Architecture
Description	Transcription factor A, mitochondrial precursor (mtTFA) (Testis- specific high mobility group protein) (TS-HMG).

TSNA1_HUMAN
θ value	1.38821 (rank : 132)	NC score	0.033117 (rank : 173)
Query Neighborhood Hits	219	Target Neighborhood Hits	178	Shared Neighborhood Hits	17
SwissProt Accessions	Q96NA8	Gene names	TSNARE1
Domain Architecture	No domain graphic available
Description	t-SNARE domain-containing protein 1.

CENPE_HUMAN
θ value	1.81305 (rank : 133)	NC score	0.046194 (rank : 143)
Query Neighborhood Hits	219	Target Neighborhood Hits	2060	Shared Neighborhood Hits	101
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

CREB3_HUMAN
θ value	1.81305 (rank : 134)	NC score	0.030272 (rank : 179)
Query Neighborhood Hits	219	Target Neighborhood Hits	138	Shared Neighborhood Hits	23
SwissProt Accessions	O43889, O14671, O14919, Q96GK8, Q9H2W3, Q9UE77	Gene names	CREB3, LZIP
Domain Architecture	No domain graphic available
Description	Cyclic AMP-responsive element-binding protein 3 (Luman protein) (Transcription factor LZIP-alpha).

FARP1_HUMAN
θ value	1.81305 (rank : 135)	NC score	0.006032 (rank : 224)
Query Neighborhood Hits	219	Target Neighborhood Hits	241	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

FES_MOUSE
θ value	1.81305 (rank : 136)	NC score	-0.000113 (rank : 230)
Query Neighborhood Hits	219	Target Neighborhood Hits	980	Shared Neighborhood Hits	32
SwissProt Accessions	P16879, Q62122	Gene names	Fes, Fps
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

GFC1_HUMAN
θ value	1.81305 (rank : 137)	NC score	0.026426 (rank : 184)
Query Neighborhood Hits	219	Target Neighborhood Hits	95	Shared Neighborhood Hits	6
SwissProt Accessions	P63117	Gene names
Domain Architecture	No domain graphic available
Description	HERV-F(c)1_Xq21.33 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein].

GLU2B_MOUSE
θ value	1.81305 (rank : 138)	NC score	0.037429 (rank : 165)
Query Neighborhood Hits	219	Target Neighborhood Hits	357	Shared Neighborhood Hits	41
SwissProt Accessions	O08795, Q921X2	Gene names	Prkcsh
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

GOGA4_MOUSE
θ value	1.81305 (rank : 139)	NC score	0.054734 (rank : 113)
Query Neighborhood Hits	219	Target Neighborhood Hits	1939	Shared Neighborhood Hits	96
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

RIN3_HUMAN
θ value	1.81305 (rank : 140)	NC score	0.023194 (rank : 190)
Query Neighborhood Hits	219	Target Neighborhood Hits	227	Shared Neighborhood Hits	20
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

ATX1_HUMAN
θ value	2.36792 (rank : 141)	NC score	0.051689 (rank : 124)
Query Neighborhood Hits	219	Target Neighborhood Hits	79	Shared Neighborhood Hits	15
SwissProt Accessions	P54253, Q9UJG2, Q9Y4J1	Gene names	ATXN1, ATX1, SCA1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein).

MYH7_HUMAN
θ value	2.36792 (rank : 142)	NC score	0.035941 (rank : 169)
Query Neighborhood Hits	219	Target Neighborhood Hits	1559	Shared Neighborhood Hits	92
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

RIN3_MOUSE
θ value	2.36792 (rank : 143)	NC score	0.039238 (rank : 162)
Query Neighborhood Hits	219	Target Neighborhood Hits	239	Shared Neighborhood Hits	20
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

SYEP_MOUSE
θ value	2.36792 (rank : 144)	NC score	0.017350 (rank : 202)
Query Neighborhood Hits	219	Target Neighborhood Hits	123	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CGC7	Gene names	Eprs, Qprs
Domain Architecture	No domain graphic available
Description	Bifunctional aminoacyl-tRNA synthetase [Includes: Glutamyl-tRNA synthetase (EC 6.1.1.17) (Glutamate--tRNA ligase); Prolyl-tRNA synthetase (EC 6.1.1.15) (Proline--tRNA ligase)].

TUFT1_HUMAN
θ value	2.36792 (rank : 145)	NC score	0.044278 (rank : 149)
Query Neighborhood Hits	219	Target Neighborhood Hits	686	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NNX1, Q5T384, Q5T385, Q9BU28, Q9H5L1	Gene names	TUFT1
Domain Architecture	No domain graphic available
Description	Tuftelin.

TUFT1_MOUSE
θ value	2.36792 (rank : 146)	NC score	0.046531 (rank : 142)
Query Neighborhood Hits	219	Target Neighborhood Hits	732	Shared Neighborhood Hits	75
SwissProt Accessions	O08970	Gene names	Tuft1
Domain Architecture
Description	Tuftelin.

ANLN_HUMAN
θ value	3.0926 (rank : 147)	NC score	0.013666 (rank : 207)
Query Neighborhood Hits	219	Target Neighborhood Hits	222	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NQW6, Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0	Gene names	ANLN
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

CENPK_MOUSE
θ value	3.0926 (rank : 148)	NC score	0.031313 (rank : 176)
Query Neighborhood Hits	219	Target Neighborhood Hits	149	Shared Neighborhood Hits	28
SwissProt Accessions	Q9ESN5, Q3UXA9, Q569Q3, Q8C469	Gene names	Cenpk, Solt
Domain Architecture	No domain graphic available
Description	Centromere protein K (CENP-K) (SoxLZ/Sox6 leucine zipper-binding protein in testis).

CP135_HUMAN
θ value	3.0926 (rank : 149)	NC score	0.049744 (rank : 134)
Query Neighborhood Hits	219	Target Neighborhood Hits	1290	Shared Neighborhood Hits	85
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

GCC2_MOUSE
θ value	3.0926 (rank : 150)	NC score	0.049343 (rank : 136)
Query Neighborhood Hits	219	Target Neighborhood Hits	1619	Shared Neighborhood Hits	97
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

KTN1_MOUSE
θ value	3.0926 (rank : 151)	NC score	0.047479 (rank : 137)
Query Neighborhood Hits	219	Target Neighborhood Hits	1324	Shared Neighborhood Hits	90
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

MRCKB_MOUSE
θ value	3.0926 (rank : 152)	NC score	0.025859 (rank : 186)
Query Neighborhood Hits	219	Target Neighborhood Hits	2180	Shared Neighborhood Hits	100
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

NEMO_HUMAN
θ value	3.0926 (rank : 153)	NC score	0.051251 (rank : 129)
Query Neighborhood Hits	219	Target Neighborhood Hits	820	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Y6K9	Gene names	IKBKG, FIP3, NEMO
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (FIP-3).

PACS1_HUMAN
θ value	3.0926 (rank : 154)	NC score	0.024954 (rank : 188)
Query Neighborhood Hits	219	Target Neighborhood Hits	82	Shared Neighborhood Hits	13
SwissProt Accessions	Q6VY07, Q6PJY6, Q6PKB6, Q7Z590, Q7Z5W4, Q8N8K6, Q96MW0, Q9NW92, Q9ULP5	Gene names	PACS1, KIAA1175
Domain Architecture	No domain graphic available
Description	Phosphofurin acidic cluster sorting protein 1 (PACS-1).

RBCC1_HUMAN
θ value	3.0926 (rank : 155)	NC score	0.051486 (rank : 127)
Query Neighborhood Hits	219	Target Neighborhood Hits	1023	Shared Neighborhood Hits	82
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

SPEG_MOUSE
θ value	3.0926 (rank : 156)	NC score	0.003791 (rank : 227)
Query Neighborhood Hits	219	Target Neighborhood Hits	1959	Shared Neighborhood Hits	40
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

APC_MOUSE
θ value	4.03905 (rank : 157)	NC score	0.029326 (rank : 180)
Query Neighborhood Hits	219	Target Neighborhood Hits	441	Shared Neighborhood Hits	60
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

CJ078_MOUSE
θ value	4.03905 (rank : 158)	NC score	0.039313 (rank : 161)
Query Neighborhood Hits	219	Target Neighborhood Hits	559	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

DESP_HUMAN
θ value	4.03905 (rank : 159)	NC score	0.042274 (rank : 152)
Query Neighborhood Hits	219	Target Neighborhood Hits	1470	Shared Neighborhood Hits	92
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

DYHC_HUMAN
θ value	4.03905 (rank : 160)	NC score	0.040726 (rank : 157)
Query Neighborhood Hits	219	Target Neighborhood Hits	733	Shared Neighborhood Hits	74
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYHC_MOUSE
θ value	4.03905 (rank : 161)	NC score	0.040688 (rank : 158)
Query Neighborhood Hits	219	Target Neighborhood Hits	729	Shared Neighborhood Hits	74
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

HM2L1_HUMAN
θ value	4.03905 (rank : 162)	NC score	0.364427 (rank : 70)
Query Neighborhood Hits	219	Target Neighborhood Hits	130	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UGU5, O75672, O75673, Q9UMT5	Gene names	HMG2L1, HMGBCG
Domain Architecture
Description	High mobility group protein 2-like 1 (Protein HMGBCG).

MYH2_HUMAN
θ value	4.03905 (rank : 163)	NC score	0.036636 (rank : 167)
Query Neighborhood Hits	219	Target Neighborhood Hits	1491	Shared Neighborhood Hits	88
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

TIM44_MOUSE
θ value	4.03905 (rank : 164)	NC score	0.021605 (rank : 192)
Query Neighborhood Hits	219	Target Neighborhood Hits	235	Shared Neighborhood Hits	32
SwissProt Accessions	O35857	Gene names	Timm44, Mimt44, Tim44
Domain Architecture
Description	Import inner membrane translocase subunit TIM44, mitochondrial precursor.

XYLT1_HUMAN
θ value	4.03905 (rank : 165)	NC score	0.013215 (rank : 209)
Query Neighborhood Hits	219	Target Neighborhood Hits	87	Shared Neighborhood Hits	5
SwissProt Accessions	Q86Y38, Q9H1B6	Gene names	XYLT1, XT1
Domain Architecture	No domain graphic available
Description	Xylosyltransferase 1 (EC 2.4.2.26) (Xylosyltransferase I) (XylT-I) (XT-I) (Peptide O-xylosyltransferase 1).

ALMS1_HUMAN
θ value	5.27518 (rank : 166)	NC score	0.021245 (rank : 195)
Query Neighborhood Hits	219	Target Neighborhood Hits	356	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TCU4, Q53S05, Q580Q8, Q86VP9, Q9Y4G4	Gene names	ALMS1, KIAA0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1.

BPA1_MOUSE
θ value	5.27518 (rank : 167)	NC score	0.031399 (rank : 175)
Query Neighborhood Hits	219	Target Neighborhood Hits	1477	Shared Neighborhood Hits	86
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CRTC1_HUMAN
θ value	5.27518 (rank : 168)	NC score	0.049443 (rank : 135)
Query Neighborhood Hits	219	Target Neighborhood Hits	319	Shared Neighborhood Hits	25
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

CS016_HUMAN
θ value	5.27518 (rank : 169)	NC score	0.036810 (rank : 166)
Query Neighborhood Hits	219	Target Neighborhood Hits	310	Shared Neighborhood Hits	20
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

EPN2_MOUSE
θ value	5.27518 (rank : 170)	NC score	0.017694 (rank : 201)
Query Neighborhood Hits	219	Target Neighborhood Hits	111	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CHU3, O70447, Q8BZ85	Gene names	Epn2
Domain Architecture
Description	Epsin-2 (EPS-15-interacting protein 2) (Intersectin-EH-binding protein 2) (Ibp2).

HDAC4_HUMAN
θ value	5.27518 (rank : 171)	NC score	0.021530 (rank : 194)
Query Neighborhood Hits	219	Target Neighborhood Hits	390	Shared Neighborhood Hits	60
SwissProt Accessions	P56524, Q9UND6	Gene names	HDAC4, KIAA0288
Domain Architecture
Description	Histone deacetylase 4 (HD4).

PF21A_HUMAN
θ value	5.27518 (rank : 172)	NC score	0.018708 (rank : 199)
Query Neighborhood Hits	219	Target Neighborhood Hits	303	Shared Neighborhood Hits	27
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

PF21A_MOUSE
θ value	5.27518 (rank : 173)	NC score	0.021560 (rank : 193)
Query Neighborhood Hits	219	Target Neighborhood Hits	285	Shared Neighborhood Hits	33
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

SUHW4_HUMAN
θ value	5.27518 (rank : 174)	NC score	-0.000860 (rank : 232)
Query Neighborhood Hits	219	Target Neighborhood Hits	860	Shared Neighborhood Hits	16
SwissProt Accessions	Q6N043, Q6MZM6, Q6N085, Q9H0U5, Q9HCI8, Q9NXS0	Gene names	SUHW4, KIAA1584
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 4.

TITIN_HUMAN
θ value	5.27518 (rank : 175)	NC score	0.003099 (rank : 228)
Query Neighborhood Hits	219	Target Neighborhood Hits	2923	Shared Neighborhood Hits	85
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

TRIPB_HUMAN
θ value	5.27518 (rank : 176)	NC score	0.057302 (rank : 105)
Query Neighborhood Hits	219	Target Neighborhood Hits	1587	Shared Neighborhood Hits	100
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

ADDB_MOUSE
θ value	6.88961 (rank : 177)	NC score	0.011313 (rank : 212)
Query Neighborhood Hits	219	Target Neighborhood Hits	574	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

AF10_HUMAN
θ value	6.88961 (rank : 178)	NC score	0.007469 (rank : 222)
Query Neighborhood Hits	219	Target Neighborhood Hits	198	Shared Neighborhood Hits	13
SwissProt Accessions	P55197	Gene names	MLLT10, AF10
Domain Architecture
Description	Protein AF-10.

APLP2_HUMAN
θ value	6.88961 (rank : 179)	NC score	0.017903 (rank : 200)
Query Neighborhood Hits	219	Target Neighborhood Hits	193	Shared Neighborhood Hits	29
SwissProt Accessions	Q06481	Gene names	APLP2, APPL2
Domain Architecture
Description	Amyloid-like protein 2 precursor (Amyloid protein homolog) (APPH) (CDEI box-binding protein) (CDEBP).

BCL9_HUMAN
θ value	6.88961 (rank : 180)	NC score	0.025487 (rank : 187)
Query Neighborhood Hits	219	Target Neighborhood Hits	1008	Shared Neighborhood Hits	44
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

CAR14_MOUSE
θ value	6.88961 (rank : 181)	NC score	0.045757 (rank : 146)
Query Neighborhood Hits	219	Target Neighborhood Hits	526	Shared Neighborhood Hits	69
SwissProt Accessions	Q99KF0	Gene names	Card14, Bimp2
Domain Architecture
Description	Caspase recruitment domain-containing protein 14 (Bcl10-interacting MAGUK protein 2) (Bimp2).

COPD_HUMAN
θ value	6.88961 (rank : 182)	NC score	0.012537 (rank : 211)
Query Neighborhood Hits	219	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	P48444, Q52M80	Gene names	ARCN1, COPD
Domain Architecture
Description	Coatomer subunit delta (Delta-coat protein) (Delta-COP) (Archain).

COPD_MOUSE
θ value	6.88961 (rank : 183)	NC score	0.012537 (rank : 210)
Query Neighborhood Hits	219	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	Q5XJY5	Gene names	Arcn1, Copd
Domain Architecture	No domain graphic available
Description	Coatomer subunit delta (Delta-coat protein) (Delta-COP) (Archain).

DAZP1_MOUSE
θ value	6.88961 (rank : 184)	NC score	0.005103 (rank : 226)
Query Neighborhood Hits	219	Target Neighborhood Hits	313	Shared Neighborhood Hits	13
SwissProt Accessions	Q9JII5	Gene names	Dazap1
Domain Architecture
Description	DAZ-associated protein 1 (Deleted in azoospermia-associated protein 1).

ELF4_MOUSE
θ value	6.88961 (rank : 185)	NC score	0.011079 (rank : 213)
Query Neighborhood Hits	219	Target Neighborhood Hits	191	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z2U4	Gene names	Elf4, Mef
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-4 (E74-like factor 4) (Myeloid Elf-1-like factor).

ENAM_HUMAN
θ value	6.88961 (rank : 186)	NC score	0.013643 (rank : 208)
Query Neighborhood Hits	219	Target Neighborhood Hits	227	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NRM1, Q9H3D1	Gene names	ENAM
Domain Architecture
Description	Enamelin precursor.

HAP1_MOUSE
θ value	6.88961 (rank : 187)	NC score	0.038087 (rank : 163)
Query Neighborhood Hits	219	Target Neighborhood Hits	388	Shared Neighborhood Hits	53
SwissProt Accessions	O35668, O35636	Gene names	Hap1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1).

IQEC2_MOUSE
θ value	6.88961 (rank : 188)	NC score	0.016656 (rank : 205)
Query Neighborhood Hits	219	Target Neighborhood Hits	417	Shared Neighborhood Hits	33
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

KIF4A_MOUSE
θ value	6.88961 (rank : 189)	NC score	0.032825 (rank : 174)
Query Neighborhood Hits	219	Target Neighborhood Hits	1033	Shared Neighborhood Hits	88
SwissProt Accessions	P33174	Gene names	Kif4a, Kif4, Kns4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

MAP4_HUMAN
θ value	6.88961 (rank : 190)	NC score	0.031194 (rank : 178)
Query Neighborhood Hits	219	Target Neighborhood Hits	428	Shared Neighborhood Hits	25
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MARK2_HUMAN
θ value	6.88961 (rank : 191)	NC score	-0.001044 (rank : 233)
Query Neighborhood Hits	219	Target Neighborhood Hits	1056	Shared Neighborhood Hits	25
SwissProt Accessions	Q7KZI7, Q15449, Q15524, Q5XGA3, Q68A18, Q96HB3, Q96RG0	Gene names	MARK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog).

MYH1_HUMAN
θ value	6.88961 (rank : 192)	NC score	0.036090 (rank : 168)
Query Neighborhood Hits	219	Target Neighborhood Hits	1478	Shared Neighborhood Hits	88
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

PLCB4_HUMAN
θ value	6.88961 (rank : 193)	NC score	0.040673 (rank : 159)
Query Neighborhood Hits	219	Target Neighborhood Hits	658	Shared Neighborhood Hits	72
SwissProt Accessions	Q15147, Q5JYS8, Q5JYT0, Q5JYT4, Q9BQW5, Q9BQW6, Q9BQW8, Q9UJQ2	Gene names	PLCB4
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-4) (PLC-beta-4).

RFIP3_HUMAN
θ value	6.88961 (rank : 194)	NC score	0.057115 (rank : 107)
Query Neighborhood Hits	219	Target Neighborhood Hits	1055	Shared Neighborhood Hits	84
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

UBP37_HUMAN
θ value	6.88961 (rank : 195)	NC score	0.010204 (rank : 217)
Query Neighborhood Hits	219	Target Neighborhood Hits	208	Shared Neighborhood Hits	22
SwissProt Accessions	Q86T82, Q9HCH8	Gene names	USP37, KIAA1594
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.1.2.15) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37) (Deubiquitinating enzyme 37).

ANK2_HUMAN
θ value	8.99809 (rank : 196)	NC score	0.009490 (rank : 220)
Query Neighborhood Hits	219	Target Neighborhood Hits	1615	Shared Neighborhood Hits	67
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

CEND_HUMAN
θ value	8.99809 (rank : 197)	NC score	0.009895 (rank : 219)
Query Neighborhood Hits	219	Target Neighborhood Hits	84	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N111, Q9NYM6	Gene names	CEND1, BM88
Domain Architecture	No domain graphic available
Description	Cell cycle exit and neuronal differentiation protein 1 (BM88 antigen).

CYLN2_MOUSE
θ value	8.99809 (rank : 198)	NC score	0.041928 (rank : 154)
Query Neighborhood Hits	219	Target Neighborhood Hits	1002	Shared Neighborhood Hits	80
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

DNMBP_HUMAN
θ value	8.99809 (rank : 199)	NC score	0.001980 (rank : 229)
Query Neighborhood Hits	219	Target Neighborhood Hits	413	Shared Neighborhood Hits	20
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

ERC2_HUMAN
θ value	8.99809 (rank : 200)	NC score	0.052298 (rank : 122)
Query Neighborhood Hits	219	Target Neighborhood Hits	1156	Shared Neighborhood Hits	88
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

ERC2_MOUSE
θ value	8.99809 (rank : 201)	NC score	0.051420 (rank : 128)
Query Neighborhood Hits	219	Target Neighborhood Hits	1166	Shared Neighborhood Hits	89
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

GCP4_MOUSE
θ value	8.99809 (rank : 202)	NC score	0.005596 (rank : 225)
Query Neighborhood Hits	219	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D4F8	Gene names	Tubgcp4, D2Ertd435e, Gcp4
Domain Architecture
Description	Gamma-tubulin complex component 4 (GCP-4).

GOGA1_MOUSE
θ value	8.99809 (rank : 203)	NC score	0.062923 (rank : 94)
Query Neighborhood Hits	219	Target Neighborhood Hits	994	Shared Neighborhood Hits	85
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

K1H1_MOUSE
θ value	8.99809 (rank : 204)	NC score	0.010701 (rank : 215)
Query Neighborhood Hits	219	Target Neighborhood Hits	450	Shared Neighborhood Hits	54
SwissProt Accessions	Q61765	Gene names	Krtha1, Hka1, Krt1-1
Domain Architecture
Description	Keratin, type I cuticular Ha1 (Hair keratin, type I Ha1) (HKA-1).

KMHN1_MOUSE
θ value	8.99809 (rank : 205)	NC score	0.046656 (rank : 140)
Query Neighborhood Hits	219	Target Neighborhood Hits	949	Shared Neighborhood Hits	78
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

LAMA2_HUMAN
θ value	8.99809 (rank : 206)	NC score	0.013923 (rank : 206)
Query Neighborhood Hits	219	Target Neighborhood Hits	1092	Shared Neighborhood Hits	63
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

MDC1_MOUSE
θ value	8.99809 (rank : 207)	NC score	0.017098 (rank : 204)
Query Neighborhood Hits	219	Target Neighborhood Hits	998	Shared Neighborhood Hits	41
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MTMR5_HUMAN
θ value	8.99809 (rank : 208)	NC score	0.010518 (rank : 216)
Query Neighborhood Hits	219	Target Neighborhood Hits	141	Shared Neighborhood Hits	9
SwissProt Accessions	O95248, O60228, Q5JXD8, Q5PPM2, Q96GR9, Q9UGB8	Gene names	SBF1, MTMR5
Domain Architecture
Description	SET-binding factor 1 (Sbf1) (Myotubularin-related protein 5).

NAF1_MOUSE
θ value	8.99809 (rank : 209)	NC score	0.040119 (rank : 160)
Query Neighborhood Hits	219	Target Neighborhood Hits	852	Shared Neighborhood Hits	73
SwissProt Accessions	Q9WUU8, Q922A9, Q922F7, Q9EPP8, Q9R0X3	Gene names	Tnip1, Abin, Naf1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (A20- binding inhibitor of NF-kappa-B activation) (ABIN) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).

NFAC1_HUMAN
θ value	8.99809 (rank : 210)	NC score	0.009961 (rank : 218)
Query Neighborhood Hits	219	Target Neighborhood Hits	312	Shared Neighborhood Hits	13
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

NR1D2_HUMAN
θ value	8.99809 (rank : 211)	NC score	-0.000418 (rank : 231)
Query Neighborhood Hits	219	Target Neighborhood Hits	115	Shared Neighborhood Hits	2
SwissProt Accessions	Q14995, O00402, Q86XD4	Gene names	NR1D2
Domain Architecture
Description	Orphan nuclear receptor NR1D2 (Rev-erb-beta) (EAR-1R) (Orphan nuclear hormone receptor BD73).

PCNT_HUMAN
θ value	8.99809 (rank : 212)	NC score	0.052203 (rank : 123)
Query Neighborhood Hits	219	Target Neighborhood Hits	1551	Shared Neighborhood Hits	98
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

PMS1_HUMAN
θ value	8.99809 (rank : 213)	NC score	0.215526 (rank : 81)
Query Neighborhood Hits	219	Target Neighborhood Hits	126	Shared Neighborhood Hits	73
SwissProt Accessions	P54277	Gene names	PMS1, PMSL1
Domain Architecture
Description	PMS1 protein homolog 1 (DNA mismatch repair protein PMS1).

R3HD2_MOUSE
θ value	8.99809 (rank : 214)	NC score	0.027539 (rank : 182)
Query Neighborhood Hits	219	Target Neighborhood Hits	397	Shared Neighborhood Hits	18
SwissProt Accessions	Q80TM6, Q80YB1, Q8BLS5, Q9CW50	Gene names	R3hdm2, Kiaa1002
Domain Architecture
Description	R3H domain-containing protein 2.

REST_HUMAN
θ value	8.99809 (rank : 215)	NC score	0.045833 (rank : 144)
Query Neighborhood Hits	219	Target Neighborhood Hits	1605	Shared Neighborhood Hits	96
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

ST5_HUMAN
θ value	8.99809 (rank : 216)	NC score	0.006150 (rank : 223)
Query Neighborhood Hits	219	Target Neighborhood Hits	151	Shared Neighborhood Hits	10
SwissProt Accessions	P78524, P78523, Q16492, Q7KYY2, Q7KZ12, Q8NE12, Q9BQQ6	Gene names	ST5, DENND2B, HTS1
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (HeLa tumor suppression 1) (DENN domain-containing protein 2B).

SWP70_MOUSE
θ value	8.99809 (rank : 217)	NC score	0.044335 (rank : 148)
Query Neighborhood Hits	219	Target Neighborhood Hits	1097	Shared Neighborhood Hits	84
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

UACA_MOUSE
θ value	8.99809 (rank : 218)	NC score	0.034362 (rank : 171)
Query Neighborhood Hits	219	Target Neighborhood Hits	1620	Shared Neighborhood Hits	85
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

ZIM2_HUMAN
θ value	8.99809 (rank : 219)	NC score	-0.006615 (rank : 234)
Query Neighborhood Hits	219	Target Neighborhood Hits	718	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NZV7	Gene names	ZIM2
Domain Architecture
Description	Zinc finger imprinted 2.

AMOT_HUMAN
θ value	θ > 10 (rank : 220)	NC score	0.056441 (rank : 110)
Query Neighborhood Hits	219	Target Neighborhood Hits	712	Shared Neighborhood Hits	77
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

AZI1_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.050135 (rank : 133)
Query Neighborhood Hits	219	Target Neighborhood Hits	1000	Shared Neighborhood Hits	76
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

CALD1_HUMAN
θ value	θ > 10 (rank : 222)	NC score	0.053562 (rank : 118)
Query Neighborhood Hits	219	Target Neighborhood Hits	959	Shared Neighborhood Hits	82
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

CCD11_MOUSE
θ value	θ > 10 (rank : 223)	NC score	0.054143 (rank : 115)
Query Neighborhood Hits	219	Target Neighborhood Hits	498	Shared Neighborhood Hits	68
SwissProt Accessions	Q9D439	Gene names	Ccdc11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CCD19_HUMAN
θ value	θ > 10 (rank : 224)	NC score	0.051119 (rank : 130)
Query Neighborhood Hits	219	Target Neighborhood Hits	639	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UL16	Gene names	CCDC19, NESG1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 19 (Nasopharyngeal epithelium- specific protein 1).

CCD91_MOUSE
θ value	θ > 10 (rank : 225)	NC score	0.051547 (rank : 126)
Query Neighborhood Hits	219	Target Neighborhood Hits	699	Shared Neighborhood Hits	67
SwissProt Accessions	Q9D8L5, Q8R3N8, Q9D9E8	Gene names	Ccdc91, Ggabp
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner).

CEP55_HUMAN
θ value	θ > 10 (rank : 226)	NC score	0.054898 (rank : 112)
Query Neighborhood Hits	219	Target Neighborhood Hits	504	Shared Neighborhood Hits	66
SwissProt Accessions	Q53EZ4, Q32WF5, Q3MV20, Q5VY28, Q6N034, Q96H32, Q9NVS7	Gene names	CEP55, C10orf3, URCC6
Domain Architecture	No domain graphic available
Description	Centrosome protein 55 (Up-regulated in colon cancer 6).

CEP57_MOUSE
θ value	θ > 10 (rank : 227)	NC score	0.053826 (rank : 117)
Query Neighborhood Hits	219	Target Neighborhood Hits	580	Shared Neighborhood Hits	70
SwissProt Accessions	Q8CEE0, Q6ZQJ3, Q7TN18, Q80X65, Q810F2, Q9D4J4, Q9D5S4, Q9D5W5	Gene names	Cep57, Kiaa0092, Tsp57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin).

ENAH_MOUSE
θ value	θ > 10 (rank : 228)	NC score	0.053938 (rank : 116)
Query Neighborhood Hits	219	Target Neighborhood Hits	919	Shared Neighborhood Hits	84
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

INVO_HUMAN
θ value	θ > 10 (rank : 229)	NC score	0.059022 (rank : 103)
Query Neighborhood Hits	219	Target Neighborhood Hits	636	Shared Neighborhood Hits	74
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

INVO_MOUSE
θ value	θ > 10 (rank : 230)	NC score	0.056880 (rank : 108)
Query Neighborhood Hits	219	Target Neighborhood Hits	474	Shared Neighborhood Hits	71
SwissProt Accessions	P48997	Gene names	Ivl
Domain Architecture	No domain graphic available
Description	Involucrin.

LUZP1_HUMAN
θ value	θ > 10 (rank : 231)	NC score	0.052522 (rank : 120)
Query Neighborhood Hits	219	Target Neighborhood Hits	739	Shared Neighborhood Hits	74
SwissProt Accessions	Q86V48, Q5TH93, Q8N4X3, Q8TEH1	Gene names	LUZP1
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1.

LUZP1_MOUSE
θ value	θ > 10 (rank : 232)	NC score	0.057201 (rank : 106)
Query Neighborhood Hits	219	Target Neighborhood Hits	940	Shared Neighborhood Hits	83
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

SP100_HUMAN
θ value	θ > 10 (rank : 233)	NC score	0.226175 (rank : 80)
Query Neighborhood Hits	219	Target Neighborhood Hits	117	Shared Neighborhood Hits	67
SwissProt Accessions	P23497, O75450, Q13343, Q96F70, Q96T24, Q96T95, Q9NP33, Q9UE32	Gene names	SP100
Domain Architecture
Description	Nuclear autoantigen Sp-100 (Speckled 100 kDa) (Nuclear dot-associated Sp100 protein) (Lysp100b).

TFAM_HUMAN
θ value	θ > 10 (rank : 234)	NC score	0.248902 (rank : 77)
Query Neighborhood Hits	219	Target Neighborhood Hits	156	Shared Neighborhood Hits	70
SwissProt Accessions	Q00059	Gene names	TFAM, TCF6L2
Domain Architecture
Description	Transcription factor A, mitochondrial precursor (mtTFA) (Mitochondrial transcription factor 1) (MtTF1) (Transcription factor 6-like 2).

Hits sorted by NC score

SOX5_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	219	Target Neighborhood Hits	219	Shared Neighborhood Hits	219
SwissProt Accessions	P35711, Q86UK8, Q8J017, Q8J018, Q8J019, Q8J020, Q8N1D9, Q8N7E0, Q8TEA4	Gene names	SOX5
Domain Architecture
Description	Transcription factor SOX-5.

SOX5_MOUSE
NC score	0.996992 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	219	Target Neighborhood Hits	196	Shared Neighborhood Hits	183
SwissProt Accessions	P35710, O88184, O89018	Gene names	Sox5, Sox-5
Domain Architecture
Description	Transcription factor SOX-5.

SOX6_HUMAN
NC score	0.966185 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	219	Target Neighborhood Hits	332	Shared Neighborhood Hits	138
SwissProt Accessions	P35712, Q9BXQ3, Q9BXQ4, Q9BXQ5, Q9H0I8	Gene names	SOX6
Domain Architecture
Description	Transcription factor SOX-6.

SOX6_MOUSE
NC score	0.964328 (rank : 4)	θ value	0 (rank : 4)
Query Neighborhood Hits	219	Target Neighborhood Hits	341	Shared Neighborhood Hits	139
SwissProt Accessions	P40645, Q62250, Q9QWS5	Gene names	Sox6, Sox-6
Domain Architecture
Description	Transcription factor SOX-6 (SOX-LZ).

SOX13_HUMAN
NC score	0.890351 (rank : 5)	θ value	4.98072e-83 (rank : 5)
Query Neighborhood Hits	219	Target Neighborhood Hits	464	Shared Neighborhood Hits	114
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

SOX13_MOUSE
NC score	0.886154 (rank : 6)	θ value	1.89707e-74 (rank : 6)
Query Neighborhood Hits	219	Target Neighborhood Hits	495	Shared Neighborhood Hits	113
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

SOX12_MOUSE
NC score	0.870773 (rank : 7)	θ value	7.82807e-20 (rank : 24)
Query Neighborhood Hits	219	Target Neighborhood Hits	98	Shared Neighborhood Hits	75
SwissProt Accessions	Q04890, P70417, Q6NXL2	Gene names	Sox12, Sox-12
Domain Architecture	No domain graphic available
Description	SOX-12 protein.

SOX12_HUMAN
NC score	0.868186 (rank : 8)	θ value	7.82807e-20 (rank : 23)
Query Neighborhood Hits	219	Target Neighborhood Hits	111	Shared Neighborhood Hits	74
SwissProt Accessions	O15370, Q9NUD4	Gene names	SOX12, SOX22
Domain Architecture
Description	SOX-12 protein (SOX-22 protein).

SRY_HUMAN
NC score	0.864920 (rank : 9)	θ value	2.06002e-20 (rank : 22)
Query Neighborhood Hits	219	Target Neighborhood Hits	83	Shared Neighborhood Hits	80
SwissProt Accessions	Q05066	Gene names	SRY, TDF
Domain Architecture
Description	Sex-determining region Y protein (Testis-determining factor).

SOX4_HUMAN
NC score	0.856874 (rank : 10)	θ value	8.36355e-22 (rank : 12)
Query Neighborhood Hits	219	Target Neighborhood Hits	111	Shared Neighborhood Hits	77
SwissProt Accessions	Q06945	Gene names	SOX4
Domain Architecture
Description	Transcription factor SOX-4.

SOX18_MOUSE
NC score	0.855835 (rank : 11)	θ value	3.75424e-22 (rank : 9)
Query Neighborhood Hits	219	Target Neighborhood Hits	105	Shared Neighborhood Hits	75
SwissProt Accessions	P43680, Q9EQ73	Gene names	Sox18, Sox-18
Domain Architecture
Description	Transcription factor SOX-18.

SRY_MOUSE
NC score	0.855606 (rank : 12)	θ value	5.42112e-21 (rank : 16)
Query Neighborhood Hits	219	Target Neighborhood Hits	139	Shared Neighborhood Hits	87
SwissProt Accessions	Q05738	Gene names	Sry, Tdf, Tdy
Domain Architecture
Description	Sex-determining region Y protein (Testis-determining factor).

SOX4_MOUSE
NC score	0.854807 (rank : 13)	θ value	1.42661e-21 (rank : 13)
Query Neighborhood Hits	219	Target Neighborhood Hits	108	Shared Neighborhood Hits	77
SwissProt Accessions	Q06831	Gene names	Sox4, Sox-4
Domain Architecture
Description	Transcription factor SOX-4.

SOX7_MOUSE
NC score	0.853273 (rank : 14)	θ value	2.35151e-24 (rank : 7)
Query Neighborhood Hits	219	Target Neighborhood Hits	105	Shared Neighborhood Hits	83
SwissProt Accessions	P40646, Q9R1T6	Gene names	Sox7, Sox-7
Domain Architecture
Description	Transcription factor SOX-7 (mSOX7).

SOX11_HUMAN
NC score	0.846769 (rank : 15)	θ value	3.07829e-16 (rank : 31)
Query Neighborhood Hits	219	Target Neighborhood Hits	89	Shared Neighborhood Hits	78
SwissProt Accessions	P35716	Gene names	SOX11
Domain Architecture
Description	Transcription factor SOX-11.

SOX7_HUMAN
NC score	0.846493 (rank : 16)	θ value	6.84181e-24 (rank : 8)
Query Neighborhood Hits	219	Target Neighborhood Hits	140	Shared Neighborhood Hits	80
SwissProt Accessions	Q9BT81	Gene names	SOX7
Domain Architecture
Description	Transcription factor SOX-7.

SOX11_MOUSE
NC score	0.844175 (rank : 17)	θ value	3.07829e-16 (rank : 32)
Query Neighborhood Hits	219	Target Neighborhood Hits	96	Shared Neighborhood Hits	79
SwissProt Accessions	Q7M6Y2, O35178, O89036, Q04889, Q80XF0	Gene names	Sox11, Sox-11
Domain Architecture	No domain graphic available
Description	Transcription factor SOX-11.

SOX18_HUMAN
NC score	0.843995 (rank : 18)	θ value	9.56915e-18 (rank : 26)
Query Neighborhood Hits	219	Target Neighborhood Hits	106	Shared Neighborhood Hits	76
SwissProt Accessions	P35713, Q9NPH8	Gene names	SOX18
Domain Architecture
Description	Transcription factor SOX-18.

SOX17_HUMAN
NC score	0.840760 (rank : 19)	θ value	1.74391e-19 (rank : 25)
Query Neighborhood Hits	219	Target Neighborhood Hits	108	Shared Neighborhood Hits	80
SwissProt Accessions	Q9H6I2	Gene names	SOX17
Domain Architecture
Description	Transcription factor SOX-17.

SOX21_MOUSE
NC score	0.835512 (rank : 20)	θ value	6.85773e-16 (rank : 34)
Query Neighborhood Hits	219	Target Neighborhood Hits	90	Shared Neighborhood Hits	79
SwissProt Accessions	Q811W0, Q8VH35	Gene names	Sox21
Domain Architecture	No domain graphic available
Description	Transcription factor SOX-21.

SOX21_HUMAN
NC score	0.835501 (rank : 21)	θ value	6.85773e-16 (rank : 33)
Query Neighborhood Hits	219	Target Neighborhood Hits	89	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Y651, P35715, Q15504	Gene names	SOX21, SOX25, SOXA
Domain Architecture
Description	Transcription factor SOX-21 (SOX-A).

SOX2_MOUSE
NC score	0.835231 (rank : 22)	θ value	1.2077e-20 (rank : 21)
Query Neighborhood Hits	219	Target Neighborhood Hits	90	Shared Neighborhood Hits	80
SwissProt Accessions	P48432	Gene names	Sox2, Sox-2
Domain Architecture
Description	Transcription factor SOX-2.

SOX2_HUMAN
NC score	0.835227 (rank : 23)	θ value	1.2077e-20 (rank : 20)
Query Neighborhood Hits	219	Target Neighborhood Hits	89	Shared Neighborhood Hits	80
SwissProt Accessions	P48431, Q14537	Gene names	SOX2
Domain Architecture
Description	Transcription factor SOX-2.

SOX17_MOUSE
NC score	0.834405 (rank : 24)	θ value	9.24701e-21 (rank : 17)
Query Neighborhood Hits	219	Target Neighborhood Hits	223	Shared Neighborhood Hits	85
SwissProt Accessions	Q61473, Q61472, Q62248	Gene names	Sox17, Sox-17
Domain Architecture
Description	Transcription factor SOX-17.

SOX14_MOUSE
NC score	0.834120 (rank : 25)	θ value	1.24977e-17 (rank : 28)
Query Neighborhood Hits	219	Target Neighborhood Hits	100	Shared Neighborhood Hits	81
SwissProt Accessions	Q04892, Q9JLC9, Q9JLD0, Q9QXU4	Gene names	Sox14, Sox-14
Domain Architecture
Description	Transcription factor SOX-14.

SOX14_HUMAN
NC score	0.834029 (rank : 26)	θ value	1.24977e-17 (rank : 27)
Query Neighborhood Hits	219	Target Neighborhood Hits	102	Shared Neighborhood Hits	81
SwissProt Accessions	O95416, Q3KPH7	Gene names	SOX14, SOX28
Domain Architecture
Description	Transcription factor SOX-14.

SOX8_HUMAN
NC score	0.833054 (rank : 27)	θ value	9.24701e-21 (rank : 18)
Query Neighborhood Hits	219	Target Neighborhood Hits	100	Shared Neighborhood Hits	77
SwissProt Accessions	P57073, Q9NZW2	Gene names	SOX8
Domain Architecture
Description	Transcription factor SOX-8.

SOX8_MOUSE
NC score	0.831746 (rank : 28)	θ value	9.24701e-21 (rank : 19)
Query Neighborhood Hits	219	Target Neighborhood Hits	96	Shared Neighborhood Hits	75
SwissProt Accessions	Q04886	Gene names	Sox8, Sox-8
Domain Architecture
Description	Transcription factor SOX-8.

SOX15_MOUSE
NC score	0.829985 (rank : 29)	θ value	1.09485e-13 (rank : 38)
Query Neighborhood Hits	219	Target Neighborhood Hits	100	Shared Neighborhood Hits	80
SwissProt Accessions	P43267, O70204, P70418, Q62246, Q91V00, Q91V43, Q920T1, Q9JLG2	Gene names	Sox15, Sox-15
Domain Architecture
Description	SOX-15 protein.

SOX1_HUMAN
NC score	0.828023 (rank : 30)	θ value	1.80466e-16 (rank : 29)
Query Neighborhood Hits	219	Target Neighborhood Hits	90	Shared Neighborhood Hits	80
SwissProt Accessions	O00570	Gene names	SOX1
Domain Architecture
Description	SOX-1 protein.

SOX1_MOUSE
NC score	0.826934 (rank : 31)	θ value	2.35696e-16 (rank : 30)
Query Neighborhood Hits	219	Target Neighborhood Hits	90	Shared Neighborhood Hits	80
SwissProt Accessions	P53783	Gene names	Sox1, Sox-1
Domain Architecture
Description	SOX-1 protein.

SOX15_HUMAN
NC score	0.825107 (rank : 32)	θ value	6.41864e-14 (rank : 37)
Query Neighborhood Hits	219	Target Neighborhood Hits	134	Shared Neighborhood Hits	82
SwissProt Accessions	O60248, P35717, Q9Y6W7	Gene names	SOX15, SOX12, SOX20, SOX26, SOX27
Domain Architecture
Description	SOX-15 protein (SOX-20 protein) (SOX-12 protein).

SOX3_MOUSE
NC score	0.821821 (rank : 33)	θ value	1.52774e-15 (rank : 35)
Query Neighborhood Hits	219	Target Neighborhood Hits	101	Shared Neighborhood Hits	79
SwissProt Accessions	P53784	Gene names	Sox3, Sox-3
Domain Architecture
Description	Transcription factor SOX-3.

SOX10_MOUSE
NC score	0.819031 (rank : 34)	θ value	5.42112e-21 (rank : 15)
Query Neighborhood Hits	219	Target Neighborhood Hits	110	Shared Neighborhood Hits	72
SwissProt Accessions	Q04888, O08518, O09141, O54856, P70416	Gene names	Sox10, Sox-10, Sox21
Domain Architecture
Description	Transcription factor SOX-10 (SOX-21) (Transcription factor SOX-M).

SOX3_HUMAN
NC score	0.818154 (rank : 35)	θ value	1.99529e-15 (rank : 36)
Query Neighborhood Hits	219	Target Neighborhood Hits	109	Shared Neighborhood Hits	80
SwissProt Accessions	P41225, P35714, Q9NP49	Gene names	SOX3
Domain Architecture
Description	Transcription factor SOX-3.

SOX10_HUMAN
NC score	0.817981 (rank : 36)	θ value	5.42112e-21 (rank : 14)
Query Neighborhood Hits	219	Target Neighborhood Hits	122	Shared Neighborhood Hits	72
SwissProt Accessions	P56693	Gene names	SOX10
Domain Architecture
Description	Transcription factor SOX-10.

SOX9_MOUSE
NC score	0.816325 (rank : 37)	θ value	6.40375e-22 (rank : 11)
Query Neighborhood Hits	219	Target Neighborhood Hits	188	Shared Neighborhood Hits	85
SwissProt Accessions	Q04887, Q8C7L2, Q91ZK2, Q99KQ0	Gene names	Sox9, Sox-9
Domain Architecture
Description	Transcription factor SOX-9.

SOX9_HUMAN
NC score	0.815461 (rank : 38)	θ value	6.40375e-22 (rank : 10)
Query Neighborhood Hits	219	Target Neighborhood Hits	210	Shared Neighborhood Hits	90
SwissProt Accessions	P48436	Gene names	SOX9
Domain Architecture
Description	Transcription factor SOX-9.

SOX30_MOUSE
NC score	0.743365 (rank : 39)	θ value	1.2105e-12 (rank : 40)
Query Neighborhood Hits	219	Target Neighborhood Hits	374	Shared Neighborhood Hits	95
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

SOX30_HUMAN
NC score	0.742337 (rank : 40)	θ value	1.2105e-12 (rank : 39)
Query Neighborhood Hits	219	Target Neighborhood Hits	305	Shared Neighborhood Hits	88
SwissProt Accessions	O94993, O94995, Q8IYX6	Gene names	SOX30
Domain Architecture
Description	Transcription factor SOX-30.

HBP1_MOUSE
NC score	0.662432 (rank : 41)	θ value	6.21693e-09 (rank : 43)
Query Neighborhood Hits	219	Target Neighborhood Hits	86	Shared Neighborhood Hits	77
SwissProt Accessions	Q8R316, Q3V0I4, Q8BUS3, Q8C199	Gene names	Hbp1
Domain Architecture	No domain graphic available
Description	HMG box-containing protein 1 (HMG box transcription factor 1) (High mobility group box transcription factor 1).

HBP1_HUMAN
NC score	0.659501 (rank : 42)	θ value	3.08544e-08 (rank : 46)
Query Neighborhood Hits	219	Target Neighborhood Hits	89	Shared Neighborhood Hits	76
SwissProt Accessions	O60381, Q8TBM1, Q8TE93, Q96AJ2	Gene names	HBP1
Domain Architecture	No domain graphic available
Description	HMG box-containing protein 1 (HMG box transcription factor 1) (High mobility group box transcription factor 1).

CIC_MOUSE
NC score	0.628672 (rank : 43)	θ value	2.0648e-12 (rank : 42)
Query Neighborhood Hits	219	Target Neighborhood Hits	742	Shared Neighborhood Hits	99
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

TCF7_HUMAN
NC score	0.624591 (rank : 44)	θ value	6.87365e-08 (rank : 47)
Query Neighborhood Hits	219	Target Neighborhood Hits	186	Shared Neighborhood Hits	73
SwissProt Accessions	P36402, Q9UKI4	Gene names	TCF7, TCF1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

BBX_HUMAN
NC score	0.596206 (rank : 45)	θ value	4.92598e-06 (rank : 51)
Query Neighborhood Hits	219	Target Neighborhood Hits	167	Shared Neighborhood Hits	84
SwissProt Accessions	Q8WY36, Q2TAJ1, Q7L3J8, Q7LBY8, Q8NDB0, Q8WY35, Q9H0J6	Gene names	BBX, HBP2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

CIC_HUMAN
NC score	0.592791 (rank : 46)	θ value	2.0648e-12 (rank : 41)
Query Neighborhood Hits	219	Target Neighborhood Hits	992	Shared Neighborhood Hits	106
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

BBX_MOUSE
NC score	0.586527 (rank : 47)	θ value	1.09739e-05 (rank : 54)
Query Neighborhood Hits	219	Target Neighborhood Hits	152	Shared Neighborhood Hits	77
SwissProt Accessions	Q8VBW5, Q3TZK1, Q6NXY8, Q6PEU3, Q8BQJ7, Q8C7E0, Q8CDQ0, Q8CDV1, Q8VI48, Q8VI49, Q8VI50, Q9CS94	Gene names	Bbx, Hbp2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

TCF7_MOUSE
NC score	0.585028 (rank : 48)	θ value	1.69304e-06 (rank : 50)
Query Neighborhood Hits	219	Target Neighborhood Hits	277	Shared Neighborhood Hits	73
SwissProt Accessions	Q00417	Gene names	Tcf7, Tcf-1, Tcf1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

LEF1_HUMAN
NC score	0.579940 (rank : 49)	θ value	1.80886e-08 (rank : 44)
Query Neighborhood Hits	219	Target Neighborhood Hits	150	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UJU2, Q9HAZ0	Gene names	LEF1
Domain Architecture
Description	Lymphoid enhancer-binding factor 1 (LEF-1) (T cell-specific transcription factor 1-alpha) (TCF1-alpha).

LEF1_MOUSE
NC score	0.578639 (rank : 50)	θ value	1.80886e-08 (rank : 45)
Query Neighborhood Hits	219	Target Neighborhood Hits	161	Shared Neighborhood Hits	76
SwissProt Accessions	P27782	Gene names	Lef1, Lef-1
Domain Architecture
Description	Lymphoid enhancer-binding factor 1 (LEF-1).

TF7L2_MOUSE
NC score	0.578198 (rank : 51)	θ value	1.17247e-07 (rank : 49)
Query Neighborhood Hits	219	Target Neighborhood Hits	95	Shared Neighborhood Hits	65
SwissProt Accessions	Q924A0, O70574, Q91XP2, Q91XP3, Q91XP4, Q924A1, Q9Z0V3, Q9Z0V4	Gene names	Tcf7l2, Tcf4
Domain Architecture
Description	Transcription factor 7-like 2 (HMG box transcription factor 4) (T- cell-specific transcription factor 4) (TCF-4) (mTCF-4).

TF7L2_HUMAN
NC score	0.574639 (rank : 52)	θ value	1.17247e-07 (rank : 48)
Query Neighborhood Hits	219	Target Neighborhood Hits	119	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NQB0, O00185, Q9NQB1, Q9NQB2, Q9NQB3, Q9NQB4, Q9NQB5, Q9NQB6, Q9NQB7, Q9ULC2	Gene names	TCF7L2, TCF4
Domain Architecture
Description	Transcription factor 7-like 2 (HMG box transcription factor 4) (T- cell-specific transcription factor 4) (TCF-4) (hTCF-4).

TF7L1_MOUSE
NC score	0.558061 (rank : 53)	θ value	4.92598e-06 (rank : 52)
Query Neighborhood Hits	219	Target Neighborhood Hits	131	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Z1J1, O70450, O70573	Gene names	Tcf7l1, Tcf3
Domain Architecture
Description	Transcription factor 7-like 1 (HMG box transcription factor 3) (TCF-3) (mTCF-3).

TF7L1_HUMAN
NC score	0.555020 (rank : 54)	θ value	6.43352e-06 (rank : 53)
Query Neighborhood Hits	219	Target Neighborhood Hits	129	Shared Neighborhood Hits	73
SwissProt Accessions	Q9HCS4, Q53R97, Q6PD70, Q9NP00	Gene names	TCF7L1, TCF3
Domain Architecture
Description	Transcription factor 7-like 1 (HMG box transcription factor 3) (TCF- 3).

HMGB3_HUMAN
NC score	0.528948 (rank : 55)	θ value	0.00035302 (rank : 60)
Query Neighborhood Hits	219	Target Neighborhood Hits	86	Shared Neighborhood Hits	72
SwissProt Accessions	O15347, O95556, Q6NS40	Gene names	HMGB3, HMG2A, HMG4
Domain Architecture
Description	High mobility group protein B3 (High mobility group protein 4) (HMG-4) (High mobility group protein 2a) (HMG-2a).

HMGB3_MOUSE
NC score	0.524786 (rank : 56)	θ value	0.00035302 (rank : 61)
Query Neighborhood Hits	219	Target Neighborhood Hits	88	Shared Neighborhood Hits	73
SwissProt Accessions	O54879	Gene names	Hmgb3, Hmg2a, Hmg4
Domain Architecture
Description	High mobility group protein B3 (High mobility group protein 4) (HMG-4) (High mobility group protein 2a) (HMG-2a).

SSRP1_MOUSE
NC score	0.519071 (rank : 57)	θ value	0.000158464 (rank : 57)
Query Neighborhood Hits	219	Target Neighborhood Hits	193	Shared Neighborhood Hits	92
SwissProt Accessions	Q08943, Q3U9Z2, Q3UJ75, Q4V9U4, Q8CGA6	Gene names	Ssrp1
Domain Architecture
Description	FACT complex subunit SSRP1 (Facilitates chromatin transcription complex subunit SSRP1) (Structure-specific recognition protein 1) (Recombination signal sequence recognition protein 1) (T160).

SSRP1_HUMAN
NC score	0.511688 (rank : 58)	θ value	5.44631e-05 (rank : 55)
Query Neighborhood Hits	219	Target Neighborhood Hits	187	Shared Neighborhood Hits	86
SwissProt Accessions	Q08945, Q5BJG8	Gene names	SSRP1, FACT80
Domain Architecture
Description	FACT complex subunit SSRP1 (Facilitates chromatin transcription complex subunit SSRP1) (FACT 80 kDa subunit) (FACTp80) (Chromatin- specific transcription elongation factor 80 kDa subunit) (Structure- specific recognition protein 1) (hSSRP1) (Recombination signal sequence recognition protein 1) (T160).

HM20B_HUMAN
NC score	0.511260 (rank : 59)	θ value	0.000786445 (rank : 62)
Query Neighborhood Hits	219	Target Neighborhood Hits	126	Shared Neighborhood Hits	85
SwissProt Accessions	Q9P0W2, Q6IBP8, Q8NBD5, Q9HD21, Q9Y491, Q9Y4A2	Gene names	HMG20B, BRAF35, HMGX2, SMARCE1R
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related (SMARCE1-related protein) (HMG domain protein HMG20B) (Structural DNA-binding protein BRAF35) (BRCA2- associated factor 35) (Sox-like transcriptional factor).

HMGB2_HUMAN
NC score	0.494610 (rank : 60)	θ value	0.000158464 (rank : 56)
Query Neighborhood Hits	219	Target Neighborhood Hits	114	Shared Neighborhood Hits	82
SwissProt Accessions	P26583	Gene names	HMGB2, HMG2
Domain Architecture
Description	High mobility group protein B2 (High mobility group protein 2) (HMG- 2).

HM20B_MOUSE
NC score	0.492872 (rank : 61)	θ value	0.00102713 (rank : 64)
Query Neighborhood Hits	219	Target Neighborhood Hits	122	Shared Neighborhood Hits	87
SwissProt Accessions	Q9Z104, Q9NSF7, Q9NSF8	Gene names	Hmg20b, Braf35, Hmgx2, Smarce1r
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related (SMARCE1-related protein) (HMG domain protein HMG20B) (Structural DNA-binding protein BRAF35) (BRCA2- associated factor 35).

HMGB2_MOUSE
NC score	0.482663 (rank : 62)	θ value	0.00035302 (rank : 59)
Query Neighborhood Hits	219	Target Neighborhood Hits	111	Shared Neighborhood Hits	81
SwissProt Accessions	P30681, Q3UXT1, Q9EQD5	Gene names	Hmgb2, Hmg2
Domain Architecture
Description	High mobility group protein B2 (High mobility group protein 2) (HMG- 2).

HMGB1_HUMAN
NC score	0.453690 (rank : 63)	θ value	0.00298849 (rank : 65)
Query Neighborhood Hits	219	Target Neighborhood Hits	126	Shared Neighborhood Hits	82
SwissProt Accessions	P09429, Q6IBE1	Gene names	HMGB1, HMG1
Domain Architecture
Description	High mobility group protein B1 (High mobility group protein 1) (HMG- 1).

HMGB1_MOUSE
NC score	0.453374 (rank : 64)	θ value	0.00298849 (rank : 66)
Query Neighborhood Hits	219	Target Neighborhood Hits	123	Shared Neighborhood Hits	81
SwissProt Accessions	P63158, P07155, P27109, P27428	Gene names	Hmgb1, Hmg-1, Hmg1
Domain Architecture	No domain graphic available
Description	High mobility group protein B1 (High mobility group protein 1) (HMG- 1).

UBF1_HUMAN
NC score	0.445355 (rank : 65)	θ value	0.000786445 (rank : 63)
Query Neighborhood Hits	219	Target Neighborhood Hits	415	Shared Neighborhood Hits	102
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

UBF1_MOUSE
NC score	0.443642 (rank : 66)	θ value	0.000270298 (rank : 58)
Query Neighborhood Hits	219	Target Neighborhood Hits	419	Shared Neighborhood Hits	107
SwissProt Accessions	P25976	Gene names	Ubtf, Tcfubf, Ubf-1, Ubf1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1).

HM20A_MOUSE
NC score	0.431199 (rank : 67)	θ value	0.00869519 (rank : 68)
Query Neighborhood Hits	219	Target Neighborhood Hits	348	Shared Neighborhood Hits	117
SwissProt Accessions	Q9DC33, Q3LSF9, Q6NV87, Q8BSK1, Q8C3C1, Q8CAA0, Q9CYG2	Gene names	Hmg20a, Ibraf
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (iBRAF) (Inhibitor of BRAF35) (HMG domain protein HMGX1).

HM20A_HUMAN
NC score	0.430850 (rank : 68)	θ value	0.00869519 (rank : 67)
Query Neighborhood Hits	219	Target Neighborhood Hits	343	Shared Neighborhood Hits	118
SwissProt Accessions	Q9NP66, Q53G31, Q9NSF6	Gene names	HMG20A, HMGX1
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (HMG domain-containing protein HMGX1).

HMG1X_HUMAN
NC score	0.407373 (rank : 69)	θ value	0.0736092 (rank : 82)
Query Neighborhood Hits	219	Target Neighborhood Hits	97	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UGV6	Gene names	HMG1L10
Domain Architecture
Description	High mobility group protein 1-like 10 (HMG-1L10).

HM2L1_HUMAN
NC score	0.364427 (rank : 70)	θ value	4.03905 (rank : 162)
Query Neighborhood Hits	219	Target Neighborhood Hits	130	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UGU5, O75672, O75673, Q9UMT5	Gene names	HMG2L1, HMGBCG
Domain Architecture
Description	High mobility group protein 2-like 1 (Protein HMGBCG).

SMCE1_HUMAN
NC score	0.323708 (rank : 71)	θ value	0.279714 (rank : 101)
Query Neighborhood Hits	219	Target Neighborhood Hits	272	Shared Neighborhood Hits	99
SwissProt Accessions	Q969G3, O43539	Gene names	SMARCE1, BAF57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 (BRG1-associated factor 57).

SMCE1_MOUSE
NC score	0.308379 (rank : 72)	θ value	0.279714 (rank : 102)
Query Neighborhood Hits	219	Target Neighborhood Hits	409	Shared Neighborhood Hits	106
SwissProt Accessions	O54941, Q8BPD9	Gene names	Smarce1, Baf57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator chromatin subfamily E member 1 (BRG1-associated factor 57).

TFAM_MOUSE
NC score	0.304168 (rank : 73)	θ value	1.38821 (rank : 131)
Query Neighborhood Hits	219	Target Neighborhood Hits	93	Shared Neighborhood Hits	78
SwissProt Accessions	P40630, P97894, P97906, Q543I8, Q9DBM9	Gene names	Tfam, Hmgts
Domain Architecture
Description	Transcription factor A, mitochondrial precursor (mtTFA) (Testis- specific high mobility group protein) (TS-HMG).

CN092_HUMAN
NC score	0.263748 (rank : 74)	θ value	0.0736092 (rank : 79)
Query Neighborhood Hits	219	Target Neighborhood Hits	143	Shared Neighborhood Hits	67
SwissProt Accessions	O94842	Gene names	C14orf92, KIAA0737
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

CN092_MOUSE
NC score	0.256919 (rank : 75)	θ value	0.0736092 (rank : 80)
Query Neighborhood Hits	219	Target Neighborhood Hits	206	Shared Neighborhood Hits	72
SwissProt Accessions	Q8BU11, Q80UI2, Q99PN9, Q9CS16	Gene names
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

PB1_HUMAN
NC score	0.255312 (rank : 76)	θ value	0.279714 (rank : 99)
Query Neighborhood Hits	219	Target Neighborhood Hits	261	Shared Neighborhood Hits	85
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

TFAM_HUMAN
NC score	0.248902 (rank : 77)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	219	Target Neighborhood Hits	156	Shared Neighborhood Hits	70
SwissProt Accessions	Q00059	Gene names	TFAM, TCF6L2
Domain Architecture
Description	Transcription factor A, mitochondrial precursor (mtTFA) (Mitochondrial transcription factor 1) (MtTF1) (Transcription factor 6-like 2).

TOX_MOUSE
NC score	0.239542 (rank : 78)	θ value	0.0563607 (rank : 77)
Query Neighborhood Hits	219	Target Neighborhood Hits	95	Shared Neighborhood Hits	53
SwissProt Accessions	Q66JW3, Q8BKH9, Q8BYQ5, Q8R4H0	Gene names	Tox
Domain Architecture	No domain graphic available
Description	Thymus high mobility group box protein TOX.

TOX_HUMAN
NC score	0.239247 (rank : 79)	θ value	0.0563607 (rank : 76)
Query Neighborhood Hits	219	Target Neighborhood Hits	106	Shared Neighborhood Hits	53
SwissProt Accessions	O94900, Q96AV5	Gene names	TOX, KIAA0808
Domain Architecture	No domain graphic available
Description	Thymus high mobility group box protein TOX.

SP100_HUMAN
NC score	0.226175 (rank : 80)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	219	Target Neighborhood Hits	117	Shared Neighborhood Hits	67
SwissProt Accessions	P23497, O75450, Q13343, Q96F70, Q96T24, Q96T95, Q9NP33, Q9UE32	Gene names	SP100
Domain Architecture
Description	Nuclear autoantigen Sp-100 (Speckled 100 kDa) (Nuclear dot-associated Sp100 protein) (Lysp100b).

PMS1_HUMAN
NC score	0.215526 (rank : 81)	θ value	8.99809 (rank : 213)
Query Neighborhood Hits	219	Target Neighborhood Hits	126	Shared Neighborhood Hits	73
SwissProt Accessions	P54277	Gene names	PMS1, PMSL1
Domain Architecture
Description	PMS1 protein homolog 1 (DNA mismatch repair protein PMS1).

GCX1_HUMAN
NC score	0.207339 (rank : 82)	θ value	0.365318 (rank : 105)
Query Neighborhood Hits	219	Target Neighborhood Hits	132	Shared Neighborhood Hits	55
SwissProt Accessions	Q96NM4, Q5TE33, Q5TE34, Q5TE35, Q96IC9, Q9BQN5	Gene names	GCX1, C20orf100
Domain Architecture
Description	Granulosa cell HMG box protein 1 (GCX-1).

CCD11_HUMAN
NC score	0.077984 (rank : 83)	θ value	0.813845 (rank : 117)
Query Neighborhood Hits	219	Target Neighborhood Hits	822	Shared Neighborhood Hits	81
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CUTL1_MOUSE
NC score	0.077253 (rank : 84)	θ value	0.0563607 (rank : 75)
Query Neighborhood Hits	219	Target Neighborhood Hits	1620	Shared Neighborhood Hits	95
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

CASP_HUMAN
NC score	0.074569 (rank : 85)	θ value	0.0736092 (rank : 78)
Query Neighborhood Hits	219	Target Neighborhood Hits	1131	Shared Neighborhood Hits	87
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CASP_MOUSE
NC score	0.073734 (rank : 86)	θ value	0.21417 (rank : 92)
Query Neighborhood Hits	219	Target Neighborhood Hits	1152	Shared Neighborhood Hits	86
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

HGS_HUMAN
NC score	0.071999 (rank : 87)	θ value	0.365318 (rank : 108)
Query Neighborhood Hits	219	Target Neighborhood Hits	517	Shared Neighborhood Hits	46
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

CUTL1_HUMAN
NC score	0.071303 (rank : 88)	θ value	0.0736092 (rank : 81)
Query Neighborhood Hits	219	Target Neighborhood Hits	1574	Shared Neighborhood Hits	95
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

GOGA1_HUMAN
NC score	0.069195 (rank : 89)	θ value	0.0431538 (rank : 72)
Query Neighborhood Hits	219	Target Neighborhood Hits	1222	Shared Neighborhood Hits	92
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

HGS_MOUSE
NC score	0.069105 (rank : 90)	θ value	0.365318 (rank : 109)
Query Neighborhood Hits	219	Target Neighborhood Hits	589	Shared Neighborhood Hits	52
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

CCD46_HUMAN
NC score	0.066833 (rank : 91)	θ value	0.125558 (rank : 87)
Query Neighborhood Hits	219	Target Neighborhood Hits	1430	Shared Neighborhood Hits	99
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

CF060_HUMAN
NC score	0.066426 (rank : 92)	θ value	0.0148317 (rank : 69)
Query Neighborhood Hits	219	Target Neighborhood Hits	1270	Shared Neighborhood Hits	84
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

CCD46_MOUSE
NC score	0.063156 (rank : 93)	θ value	0.0563607 (rank : 74)
Query Neighborhood Hits	219	Target Neighborhood Hits	1405	Shared Neighborhood Hits	95
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

GOGA1_MOUSE
NC score	0.062923 (rank : 94)	θ value	8.99809 (rank : 203)
Query Neighborhood Hits	219	Target Neighborhood Hits	994	Shared Neighborhood Hits	85
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

ATX1_MOUSE
NC score	0.062913 (rank : 95)	θ value	0.365318 (rank : 103)
Query Neighborhood Hits	219	Target Neighborhood Hits	264	Shared Neighborhood Hits	18
SwissProt Accessions	P54254	Gene names	Atxn1, Sca1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).

HAP1_HUMAN
NC score	0.062279 (rank : 96)	θ value	0.365318 (rank : 107)
Query Neighborhood Hits	219	Target Neighborhood Hits	606	Shared Neighborhood Hits	69
SwissProt Accessions	P54257, O75358, Q9H4G3, Q9HA98, Q9NY90	Gene names	HAP1, HLP1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1) (Neuroan 1).

RB6I2_MOUSE
NC score	0.062178 (rank : 97)	θ value	0.62314 (rank : 114)
Query Neighborhood Hits	219	Target Neighborhood Hits	1433	Shared Neighborhood Hits	94
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

AZI1_MOUSE
NC score	0.061787 (rank : 98)	θ value	0.279714 (rank : 95)
Query Neighborhood Hits	219	Target Neighborhood Hits	990	Shared Neighborhood Hits	81
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

K0555_HUMAN
NC score	0.061378 (rank : 99)	θ value	0.21417 (rank : 94)
Query Neighborhood Hits	219	Target Neighborhood Hits	880	Shared Neighborhood Hits	77
SwissProt Accessions	Q96AA8, O60302	Gene names	KIAA0555
Domain Architecture	No domain graphic available
Description	Protein KIAA0555.

IFT81_MOUSE
NC score	0.060829 (rank : 100)	θ value	0.47712 (rank : 110)
Query Neighborhood Hits	219	Target Neighborhood Hits	959	Shared Neighborhood Hits	78
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

GOGA5_HUMAN
NC score	0.060276 (rank : 101)	θ value	1.38821 (rank : 128)
Query Neighborhood Hits	219	Target Neighborhood Hits	1168	Shared Neighborhood Hits	86
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

RB6I2_HUMAN
NC score	0.059758 (rank : 102)	θ value	0.47712 (rank : 112)
Query Neighborhood Hits	219	Target Neighborhood Hits	1584	Shared Neighborhood Hits	95
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

INVO_HUMAN
NC score	0.059022 (rank : 103)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	219	Target Neighborhood Hits	636	Shared Neighborhood Hits	74
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

GOGA5_MOUSE
NC score	0.058506 (rank : 104)	θ value	0.125558 (rank : 88)
Query Neighborhood Hits	219	Target Neighborhood Hits	1434	Shared Neighborhood Hits	93
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

TRIPB_HUMAN
NC score	0.057302 (rank : 105)	θ value	5.27518 (rank : 176)
Query Neighborhood Hits	219	Target Neighborhood Hits	1587	Shared Neighborhood Hits	100
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

LUZP1_MOUSE
NC score	0.057201 (rank : 106)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	219	Target Neighborhood Hits	940	Shared Neighborhood Hits	83
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

RFIP3_HUMAN
NC score	0.057115 (rank : 107)	θ value	6.88961 (rank : 194)
Query Neighborhood Hits	219	Target Neighborhood Hits	1055	Shared Neighborhood Hits	84
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

INVO_MOUSE
NC score	0.056880 (rank : 108)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	219	Target Neighborhood Hits	474	Shared Neighborhood Hits	71
SwissProt Accessions	P48997	Gene names	Ivl
Domain Architecture	No domain graphic available
Description	Involucrin.

HIP1_HUMAN
NC score	0.056664 (rank : 109)	θ value	0.0148317 (rank : 70)
Query Neighborhood Hits	219	Target Neighborhood Hits	1016	Shared Neighborhood Hits	78
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

AMOT_HUMAN
NC score	0.056441 (rank : 110)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	219	Target Neighborhood Hits	712	Shared Neighborhood Hits	77
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

CP250_HUMAN
NC score	0.054925 (rank : 111)	θ value	0.813845 (rank : 118)
Query Neighborhood Hits	219	Target Neighborhood Hits	1805	Shared Neighborhood Hits	105
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

CEP55_HUMAN
NC score	0.054898 (rank : 112)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	219	Target Neighborhood Hits	504	Shared Neighborhood Hits	66
SwissProt Accessions	Q53EZ4, Q32WF5, Q3MV20, Q5VY28, Q6N034, Q96H32, Q9NVS7	Gene names	CEP55, C10orf3, URCC6
Domain Architecture	No domain graphic available
Description	Centrosome protein 55 (Up-regulated in colon cancer 6).

GOGA4_MOUSE
NC score	0.054734 (rank : 113)	θ value	1.81305 (rank : 139)
Query Neighborhood Hits	219	Target Neighborhood Hits	1939	Shared Neighborhood Hits	96
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

CE290_HUMAN
NC score	0.054538 (rank : 114)	θ value	1.38821 (rank : 127)
Query Neighborhood Hits	219	Target Neighborhood Hits	1553	Shared Neighborhood Hits	95
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

CCD11_MOUSE
NC score	0.054143 (rank : 115)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	219	Target Neighborhood Hits	498	Shared Neighborhood Hits	68
SwissProt Accessions	Q9D439	Gene names	Ccdc11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

ENAH_MOUSE
NC score	0.053938 (rank : 116)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	219	Target Neighborhood Hits	919	Shared Neighborhood Hits	84
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

CEP57_MOUSE
NC score	0.053826 (rank : 117)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	219	Target Neighborhood Hits	580	Shared Neighborhood Hits	70
SwissProt Accessions	Q8CEE0, Q6ZQJ3, Q7TN18, Q80X65, Q810F2, Q9D4J4, Q9D5S4, Q9D5W5	Gene names	Cep57, Kiaa0092, Tsp57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin).

CALD1_HUMAN
NC score	0.053562 (rank : 118)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	219	Target Neighborhood Hits	959	Shared Neighborhood Hits	82
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

NIN_MOUSE
NC score	0.052770 (rank : 119)	θ value	0.279714 (rank : 98)
Query Neighborhood Hits	219	Target Neighborhood Hits	1376	Shared Neighborhood Hits	89
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

LUZP1_HUMAN
NC score	0.052522 (rank : 120)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	219	Target Neighborhood Hits	739	Shared Neighborhood Hits	74
SwissProt Accessions	Q86V48, Q5TH93, Q8N4X3, Q8TEH1	Gene names	LUZP1
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1.

CEP57_HUMAN
NC score	0.052490 (rank : 121)	θ value	1.06291 (rank : 122)
Query Neighborhood Hits	219	Target Neighborhood Hits	576	Shared Neighborhood Hits	70
SwissProt Accessions	Q86XR8, Q14704, Q8IXP0, Q9BVF9	Gene names	CEP57, KIAA0092, TSP57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin) (FGF2-interacting protein).

ERC2_HUMAN
NC score	0.052298 (rank : 122)	θ value	8.99809 (rank : 200)
Query Neighborhood Hits	219	Target Neighborhood Hits	1156	Shared Neighborhood Hits	88
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

PCNT_HUMAN
NC score	0.052203 (rank : 123)	θ value	8.99809 (rank : 212)
Query Neighborhood Hits	219	Target Neighborhood Hits	1551	Shared Neighborhood Hits	98
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

ATX1_HUMAN
NC score	0.051689 (rank : 124)	θ value	2.36792 (rank : 141)
Query Neighborhood Hits	219	Target Neighborhood Hits	79	Shared Neighborhood Hits	15
SwissProt Accessions	P54253, Q9UJG2, Q9Y4J1	Gene names	ATXN1, ATX1, SCA1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein).

GOGA4_HUMAN
NC score	0.051637 (rank : 125)	θ value	1.06291 (rank : 123)
Query Neighborhood Hits	219	Target Neighborhood Hits	2034	Shared Neighborhood Hits	103
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

CCD91_MOUSE
NC score	0.051547 (rank : 126)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	219	Target Neighborhood Hits	699	Shared Neighborhood Hits	67
SwissProt Accessions	Q9D8L5, Q8R3N8, Q9D9E8	Gene names	Ccdc91, Ggabp
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner).

RBCC1_HUMAN
NC score	0.051486 (rank : 127)	θ value	3.0926 (rank : 155)
Query Neighborhood Hits	219	Target Neighborhood Hits	1023	Shared Neighborhood Hits	82
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

ERC2_MOUSE
NC score	0.051420 (rank : 128)	θ value	8.99809 (rank : 201)
Query Neighborhood Hits	219	Target Neighborhood Hits	1166	Shared Neighborhood Hits	89
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

NEMO_HUMAN
NC score	0.051251 (rank : 129)	θ value	3.0926 (rank : 153)
Query Neighborhood Hits	219	Target Neighborhood Hits	820	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Y6K9	Gene names	IKBKG, FIP3, NEMO
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (FIP-3).

CCD19_HUMAN
NC score	0.051119 (rank : 130)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	219	Target Neighborhood Hits	639	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UL16	Gene names	CCDC19, NESG1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 19 (Nasopharyngeal epithelium- specific protein 1).

CENPF_HUMAN
NC score	0.050699 (rank : 131)	θ value	1.06291 (rank : 121)
Query Neighborhood Hits	219	Target Neighborhood Hits	1932	Shared Neighborhood Hits	98
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

GOGA3_MOUSE
NC score	0.050281 (rank : 132)	θ value	0.365318 (rank : 106)
Query Neighborhood Hits	219	Target Neighborhood Hits	1437	Shared Neighborhood Hits	85
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

AZI1_HUMAN
NC score	0.050135 (rank : 133)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	219	Target Neighborhood Hits	1000	Shared Neighborhood Hits	76
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

CP135_HUMAN
NC score	0.049744 (rank : 134)	θ value	3.0926 (rank : 149)
Query Neighborhood Hits	219	Target Neighborhood Hits	1290	Shared Neighborhood Hits	85
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CRTC1_HUMAN
NC score	0.049443 (rank : 135)	θ value	5.27518 (rank : 168)
Query Neighborhood Hits	219	Target Neighborhood Hits	319	Shared Neighborhood Hits	25
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

GCC2_MOUSE
NC score	0.049343 (rank : 136)	θ value	3.0926 (rank : 150)
Query Neighborhood Hits	219	Target Neighborhood Hits	1619	Shared Neighborhood Hits	97
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

KTN1_MOUSE
NC score	0.047479 (rank : 137)	θ value	3.0926 (rank : 151)
Query Neighborhood Hits	219	Target Neighborhood Hits	1324	Shared Neighborhood Hits	90
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

BPAEA_MOUSE
NC score	0.047088 (rank : 138)	θ value	1.06291 (rank : 120)
Query Neighborhood Hits	219	Target Neighborhood Hits	1480	Shared Neighborhood Hits	91
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

GOGB1_HUMAN
NC score	0.046658 (rank : 139)	θ value	0.21417 (rank : 93)
Query Neighborhood Hits	219	Target Neighborhood Hits	2297	Shared Neighborhood Hits	104
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

KMHN1_MOUSE
NC score	0.046656 (rank : 140)	θ value	8.99809 (rank : 205)
Query Neighborhood Hits	219	Target Neighborhood Hits	949	Shared Neighborhood Hits	78
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

MY18A_MOUSE
NC score	0.046626 (rank : 141)	θ value	0.279714 (rank : 97)
Query Neighborhood Hits	219	Target Neighborhood Hits	1989	Shared Neighborhood Hits	102
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

TUFT1_MOUSE
NC score	0.046531 (rank : 142)	θ value	2.36792 (rank : 146)
Query Neighborhood Hits	219	Target Neighborhood Hits	732	Shared Neighborhood Hits	75
SwissProt Accessions	O08970	Gene names	Tuft1
Domain Architecture
Description	Tuftelin.

CENPE_HUMAN
NC score	0.046194 (rank : 143)	θ value	1.81305 (rank : 133)
Query Neighborhood Hits	219	Target Neighborhood Hits	2060	Shared Neighborhood Hits	101
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

REST_HUMAN
NC score	0.045833 (rank : 144)	θ value	8.99809 (rank : 215)
Query Neighborhood Hits	219	Target Neighborhood Hits	1605	Shared Neighborhood Hits	96
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

MY18A_HUMAN
NC score	0.045792 (rank : 145)	θ value	0.279714 (rank : 96)
Query Neighborhood Hits	219	Target Neighborhood Hits	1929	Shared Neighborhood Hits	97
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

CAR14_MOUSE
NC score	0.045757 (rank : 146)	θ value	6.88961 (rank : 181)
Query Neighborhood Hits	219	Target Neighborhood Hits	526	Shared Neighborhood Hits	69
SwissProt Accessions	Q99KF0	Gene names	Card14, Bimp2
Domain Architecture
Description	Caspase recruitment domain-containing protein 14 (Bcl10-interacting MAGUK protein 2) (Bimp2).

MAP4_MOUSE
NC score	0.045011 (rank : 147)	θ value	0.0431538 (rank : 73)
Query Neighborhood Hits	219	Target Neighborhood Hits	409	Shared Neighborhood Hits	23
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

SWP70_MOUSE
NC score	0.044335 (rank : 148)	θ value	8.99809 (rank : 217)
Query Neighborhood Hits	219	Target Neighborhood Hits	1097	Shared Neighborhood Hits	84
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

TUFT1_HUMAN
NC score	0.044278 (rank : 149)	θ value	2.36792 (rank : 145)
Query Neighborhood Hits	219	Target Neighborhood Hits	686	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NNX1, Q5T384, Q5T385, Q9BU28, Q9H5L1	Gene names	TUFT1
Domain Architecture	No domain graphic available
Description	Tuftelin.

TFEB_HUMAN
NC score	0.043605 (rank : 150)	θ value	0.0330416 (rank : 71)
Query Neighborhood Hits	219	Target Neighborhood Hits	111	Shared Neighborhood Hits	10
SwissProt Accessions	P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8	Gene names	TFEB
Domain Architecture
Description	Transcription factor EB.

ACINU_MOUSE
NC score	0.043048 (rank : 151)	θ value	0.813845 (rank : 115)
Query Neighborhood Hits	219	Target Neighborhood Hits	712	Shared Neighborhood Hits	72
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

DESP_HUMAN
NC score	0.042274 (rank : 152)	θ value	4.03905 (rank : 159)
Query Neighborhood Hits	219	Target Neighborhood Hits	1470	Shared Neighborhood Hits	92
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

HOME2_MOUSE
NC score	0.042067 (rank : 153)	θ value	0.62314 (rank : 113)
Query Neighborhood Hits	219	Target Neighborhood Hits	882	Shared Neighborhood Hits	76
SwissProt Accessions	Q9QWW1, O89025, Q9Z0E4	Gene names	Homer2, Vesl2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up- regulated during seizure and LTP 2) (Vesl-2).

CYLN2_MOUSE
NC score	0.041928 (rank : 154)	θ value	8.99809 (rank : 198)
Query Neighborhood Hits	219	Target Neighborhood Hits	1002	Shared Neighborhood Hits	80
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

TFEB_MOUSE
NC score	0.041736 (rank : 155)	θ value	0.163984 (rank : 91)
Query Neighborhood Hits	219	Target Neighborhood Hits	119	Shared Neighborhood Hits	12
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

SYGP1_HUMAN
NC score	0.041725 (rank : 156)	θ value	0.0961366 (rank : 86)
Query Neighborhood Hits	219	Target Neighborhood Hits	589	Shared Neighborhood Hits	62
SwissProt Accessions	Q96PV0, Q8TCS2, Q9UGE2	Gene names	SYNGAP1, KIAA1938
Domain Architecture
Description	Ras GTPase-activating protein SynGAP (Synaptic Ras-GTPase-activating protein 1) (Synaptic Ras-GAP 1) (Neuronal RasGAP).

DYHC_HUMAN
NC score	0.040726 (rank : 157)	θ value	4.03905 (rank : 160)
Query Neighborhood Hits	219	Target Neighborhood Hits	733	Shared Neighborhood Hits	74
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYHC_MOUSE
NC score	0.040688 (rank : 158)	θ value	4.03905 (rank : 161)
Query Neighborhood Hits	219	Target Neighborhood Hits	729	Shared Neighborhood Hits	74
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

PLCB4_HUMAN
NC score	0.040673 (rank : 159)	θ value	6.88961 (rank : 193)
Query Neighborhood Hits	219	Target Neighborhood Hits	658	Shared Neighborhood Hits	72
SwissProt Accessions	Q15147, Q5JYS8, Q5JYT0, Q5JYT4, Q9BQW5, Q9BQW6, Q9BQW8, Q9UJQ2	Gene names	PLCB4
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-4) (PLC-beta-4).

NAF1_MOUSE
NC score	0.040119 (rank : 160)	θ value	8.99809 (rank : 209)
Query Neighborhood Hits	219	Target Neighborhood Hits	852	Shared Neighborhood Hits	73
SwissProt Accessions	Q9WUU8, Q922A9, Q922F7, Q9EPP8, Q9R0X3	Gene names	Tnip1, Abin, Naf1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (A20- binding inhibitor of NF-kappa-B activation) (ABIN) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).

CJ078_MOUSE
NC score	0.039313 (rank : 161)	θ value	4.03905 (rank : 158)
Query Neighborhood Hits	219	Target Neighborhood Hits	559	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

RIN3_MOUSE
NC score	0.039238 (rank : 162)	θ value	2.36792 (rank : 143)
Query Neighborhood Hits	219	Target Neighborhood Hits	239	Shared Neighborhood Hits	20
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

HAP1_MOUSE
NC score	0.038087 (rank : 163)	θ value	6.88961 (rank : 187)
Query Neighborhood Hits	219	Target Neighborhood Hits	388	Shared Neighborhood Hits	53
SwissProt Accessions	O35668, O35636	Gene names	Hap1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1).

MLL3_HUMAN
NC score	0.037808 (rank : 164)	θ value	0.813845 (rank : 119)
Query Neighborhood Hits	219	Target Neighborhood Hits	1644	Shared Neighborhood Hits	82
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

GLU2B_MOUSE
NC score	0.037429 (rank : 165)	θ value	1.81305 (rank : 138)
Query Neighborhood Hits	219	Target Neighborhood Hits	357	Shared Neighborhood Hits	41
SwissProt Accessions	O08795, Q921X2	Gene names	Prkcsh
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

CS016_HUMAN
NC score	0.036810 (rank : 166)	θ value	5.27518 (rank : 169)
Query Neighborhood Hits	219	Target Neighborhood Hits	310	Shared Neighborhood Hits	20
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

MYH2_HUMAN
NC score	0.036636 (rank : 167)	θ value	4.03905 (rank : 163)
Query Neighborhood Hits	219	Target Neighborhood Hits	1491	Shared Neighborhood Hits	88
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

MYH1_HUMAN
NC score	0.036090 (rank : 168)	θ value	6.88961 (rank : 192)
Query Neighborhood Hits	219	Target Neighborhood Hits	1478	Shared Neighborhood Hits	88
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

MYH7_HUMAN
NC score	0.035941 (rank : 169)	θ value	2.36792 (rank : 142)
Query Neighborhood Hits	219	Target Neighborhood Hits	1559	Shared Neighborhood Hits	92
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

LMNB2_HUMAN
NC score	0.034364 (rank : 170)	θ value	1.38821 (rank : 129)
Query Neighborhood Hits	219	Target Neighborhood Hits	723	Shared Neighborhood Hits	73
SwissProt Accessions	Q03252, O75292, Q14734, Q96DF6	Gene names	LMNB2, LMN2
Domain Architecture
Description	Lamin-B2.

UACA_MOUSE
NC score	0.034362 (rank : 171)	θ value	8.99809 (rank : 218)
Query Neighborhood Hits	219	Target Neighborhood Hits	1620	Shared Neighborhood Hits	85
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

RAI14_MOUSE
NC score	0.034359 (rank : 172)	θ value	0.279714 (rank : 100)
Query Neighborhood Hits	219	Target Neighborhood Hits	1505	Shared Neighborhood Hits	86
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

TSNA1_HUMAN
NC score	0.033117 (rank : 173)	θ value	1.38821 (rank : 132)
Query Neighborhood Hits	219	Target Neighborhood Hits	178	Shared Neighborhood Hits	17
SwissProt Accessions	Q96NA8	Gene names	TSNARE1
Domain Architecture	No domain graphic available
Description	t-SNARE domain-containing protein 1.

KIF4A_MOUSE
NC score	0.032825 (rank : 174)	θ value	6.88961 (rank : 189)
Query Neighborhood Hits	219	Target Neighborhood Hits	1033	Shared Neighborhood Hits	88
SwissProt Accessions	P33174	Gene names	Kif4a, Kif4, Kns4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

BPA1_MOUSE
NC score	0.031399 (rank : 175)	θ value	5.27518 (rank : 167)
Query Neighborhood Hits	219	Target Neighborhood Hits	1477	Shared Neighborhood Hits	86
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CENPK_MOUSE
NC score	0.031313 (rank : 176)	θ value	3.0926 (rank : 148)
Query Neighborhood Hits	219	Target Neighborhood Hits	149	Shared Neighborhood Hits	28
SwissProt Accessions	Q9ESN5, Q3UXA9, Q569Q3, Q8C469	Gene names	Cenpk, Solt
Domain Architecture	No domain graphic available
Description	Centromere protein K (CENP-K) (SoxLZ/Sox6 leucine zipper-binding protein in testis).

LIPS_MOUSE
NC score	0.031246 (rank : 177)	θ value	1.06291 (rank : 125)
Query Neighborhood Hits	219	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	P54310, P97866, Q3TE34, Q6GU16	Gene names	Lipe
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

MAP4_HUMAN
NC score	0.031194 (rank : 178)	θ value	6.88961 (rank : 190)
Query Neighborhood Hits	219	Target Neighborhood Hits	428	Shared Neighborhood Hits	25
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

CREB3_HUMAN
NC score	0.030272 (rank : 179)	θ value	1.81305 (rank : 134)
Query Neighborhood Hits	219	Target Neighborhood Hits	138	Shared Neighborhood Hits	23
SwissProt Accessions	O43889, O14671, O14919, Q96GK8, Q9H2W3, Q9UE77	Gene names	CREB3, LZIP
Domain Architecture	No domain graphic available
Description	Cyclic AMP-responsive element-binding protein 3 (Luman protein) (Transcription factor LZIP-alpha).

APC_MOUSE
NC score	0.029326 (rank : 180)	θ value	4.03905 (rank : 157)
Query Neighborhood Hits	219	Target Neighborhood Hits	441	Shared Neighborhood Hits	60
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

PRRT3_HUMAN
NC score	0.028897 (rank : 181)	θ value	1.38821 (rank : 130)
Query Neighborhood Hits	219	Target Neighborhood Hits	998	Shared Neighborhood Hits	46
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

R3HD2_MOUSE
NC score	0.027539 (rank : 182)	θ value	8.99809 (rank : 214)
Query Neighborhood Hits	219	Target Neighborhood Hits	397	Shared Neighborhood Hits	18
SwissProt Accessions	Q80TM6, Q80YB1, Q8BLS5, Q9CW50	Gene names	R3hdm2, Kiaa1002
Domain Architecture
Description	R3H domain-containing protein 2.

BAZ2A_MOUSE
NC score	0.026498 (rank : 183)	θ value	0.163984 (rank : 90)
Query Neighborhood Hits	219	Target Neighborhood Hits	744	Shared Neighborhood Hits	46
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

GFC1_HUMAN
NC score	0.026426 (rank : 184)	θ value	1.81305 (rank : 137)
Query Neighborhood Hits	219	Target Neighborhood Hits	95	Shared Neighborhood Hits	6
SwissProt Accessions	P63117	Gene names
Domain Architecture	No domain graphic available
Description	HERV-F(c)1_Xq21.33 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein].

MRCKB_HUMAN
NC score	0.025959 (rank : 185)	θ value	0.0961366 (rank : 85)
Query Neighborhood Hits	219	Target Neighborhood Hits	2239	Shared Neighborhood Hits	100
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

MRCKB_MOUSE
NC score	0.025859 (rank : 186)	θ value	3.0926 (rank : 152)
Query Neighborhood Hits	219	Target Neighborhood Hits	2180	Shared Neighborhood Hits	100
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

BCL9_HUMAN
NC score	0.025487 (rank : 187)	θ value	6.88961 (rank : 180)
Query Neighborhood Hits	219	Target Neighborhood Hits	1008	Shared Neighborhood Hits	44
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

PACS1_HUMAN
NC score	0.024954 (rank : 188)	θ value	3.0926 (rank : 154)
Query Neighborhood Hits	219	Target Neighborhood Hits	82	Shared Neighborhood Hits	13
SwissProt Accessions	Q6VY07, Q6PJY6, Q6PKB6, Q7Z590, Q7Z5W4, Q8N8K6, Q96MW0, Q9NW92, Q9ULP5	Gene names	PACS1, KIAA1175
Domain Architecture	No domain graphic available
Description	Phosphofurin acidic cluster sorting protein 1 (PACS-1).

STK10_MOUSE
NC score	0.023735 (rank : 189)	θ value	0.125558 (rank : 89)
Query Neighborhood Hits	219	Target Neighborhood Hits	2132	Shared Neighborhood Hits	93
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

RIN3_HUMAN
NC score	0.023194 (rank : 190)	θ value	1.81305 (rank : 140)
Query Neighborhood Hits	219	Target Neighborhood Hits	227	Shared Neighborhood Hits	20
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

STK10_HUMAN
NC score	0.022659 (rank : 191)	θ value	0.0736092 (rank : 84)
Query Neighborhood Hits	219	Target Neighborhood Hits	1921	Shared Neighborhood Hits	87
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

TIM44_MOUSE
NC score	0.021605 (rank : 192)	θ value	4.03905 (rank : 164)
Query Neighborhood Hits	219	Target Neighborhood Hits	235	Shared Neighborhood Hits	32
SwissProt Accessions	O35857	Gene names	Timm44, Mimt44, Tim44
Domain Architecture
Description	Import inner membrane translocase subunit TIM44, mitochondrial precursor.

PF21A_MOUSE
NC score	0.021560 (rank : 193)	θ value	5.27518 (rank : 173)
Query Neighborhood Hits	219	Target Neighborhood Hits	285	Shared Neighborhood Hits	33
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

HDAC4_HUMAN
NC score	0.021530 (rank : 194)	θ value	5.27518 (rank : 171)
Query Neighborhood Hits	219	Target Neighborhood Hits	390	Shared Neighborhood Hits	60
SwissProt Accessions	P56524, Q9UND6	Gene names	HDAC4, KIAA0288
Domain Architecture
Description	Histone deacetylase 4 (HD4).

ALMS1_HUMAN
NC score	0.021245 (rank : 195)	θ value	5.27518 (rank : 166)
Query Neighborhood Hits	219	Target Neighborhood Hits	356	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TCU4, Q53S05, Q580Q8, Q86VP9, Q9Y4G4	Gene names	ALMS1, KIAA0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1.

JHD2C_MOUSE
NC score	0.020843 (rank : 196)	θ value	1.06291 (rank : 124)
Query Neighborhood Hits	219	Target Neighborhood Hits	297	Shared Neighborhood Hits	12
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

AF9_HUMAN
NC score	0.020445 (rank : 197)	θ value	0.813845 (rank : 116)
Query Neighborhood Hits	219	Target Neighborhood Hits	202	Shared Neighborhood Hits	11
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

MAGE1_HUMAN
NC score	0.019782 (rank : 198)	θ value	0.0736092 (rank : 83)
Query Neighborhood Hits	219	Target Neighborhood Hits	1389	Shared Neighborhood Hits	39
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

PF21A_HUMAN
NC score	0.018708 (rank : 199)	θ value	5.27518 (rank : 172)
Query Neighborhood Hits	219	Target Neighborhood Hits	303	Shared Neighborhood Hits	27
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

APLP2_HUMAN
NC score	0.017903 (rank : 200)	θ value	6.88961 (rank : 179)
Query Neighborhood Hits	219	Target Neighborhood Hits	193	Shared Neighborhood Hits	29
SwissProt Accessions	Q06481	Gene names	APLP2, APPL2
Domain Architecture
Description	Amyloid-like protein 2 precursor (Amyloid protein homolog) (APPH) (CDEI box-binding protein) (CDEBP).

EPN2_MOUSE
NC score	0.017694 (rank : 201)	θ value	5.27518 (rank : 170)
Query Neighborhood Hits	219	Target Neighborhood Hits	111	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CHU3, O70447, Q8BZ85	Gene names	Epn2
Domain Architecture
Description	Epsin-2 (EPS-15-interacting protein 2) (Intersectin-EH-binding protein 2) (Ibp2).

SYEP_MOUSE
NC score	0.017350 (rank : 202)	θ value	2.36792 (rank : 144)
Query Neighborhood Hits	219	Target Neighborhood Hits	123	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CGC7	Gene names	Eprs, Qprs
Domain Architecture	No domain graphic available
Description	Bifunctional aminoacyl-tRNA synthetase [Includes: Glutamyl-tRNA synthetase (EC 6.1.1.17) (Glutamate--tRNA ligase); Prolyl-tRNA synthetase (EC 6.1.1.15) (Proline--tRNA ligase)].

E41L2_MOUSE
NC score	0.017234 (rank : 203)	θ value	0.365318 (rank : 104)
Query Neighborhood Hits	219	Target Neighborhood Hits	459	Shared Neighborhood Hits	35
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

MDC1_MOUSE
NC score	0.017098 (rank : 204)	θ value	8.99809 (rank : 207)
Query Neighborhood Hits	219	Target Neighborhood Hits	998	Shared Neighborhood Hits	41
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

IQEC2_MOUSE
NC score	0.016656 (rank : 205)	θ value	6.88961 (rank : 188)
Query Neighborhood Hits	219	Target Neighborhood Hits	417	Shared Neighborhood Hits	33
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

LAMA2_HUMAN
NC score	0.013923 (rank : 206)	θ value	8.99809 (rank : 206)
Query Neighborhood Hits	219	Target Neighborhood Hits	1092	Shared Neighborhood Hits	63
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

ANLN_HUMAN
NC score	0.013666 (rank : 207)	θ value	3.0926 (rank : 147)
Query Neighborhood Hits	219	Target Neighborhood Hits	222	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NQW6, Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0	Gene names	ANLN
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

ENAM_HUMAN
NC score	0.013643 (rank : 208)	θ value	6.88961 (rank : 186)
Query Neighborhood Hits	219	Target Neighborhood Hits	227	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NRM1, Q9H3D1	Gene names	ENAM
Domain Architecture
Description	Enamelin precursor.

XYLT1_HUMAN
NC score	0.013215 (rank : 209)	θ value	4.03905 (rank : 165)
Query Neighborhood Hits	219	Target Neighborhood Hits	87	Shared Neighborhood Hits	5
SwissProt Accessions	Q86Y38, Q9H1B6	Gene names	XYLT1, XT1
Domain Architecture	No domain graphic available
Description	Xylosyltransferase 1 (EC 2.4.2.26) (Xylosyltransferase I) (XylT-I) (XT-I) (Peptide O-xylosyltransferase 1).

COPD_MOUSE
NC score	0.012537 (rank : 210)	θ value	6.88961 (rank : 183)
Query Neighborhood Hits	219	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	Q5XJY5	Gene names	Arcn1, Copd
Domain Architecture	No domain graphic available
Description	Coatomer subunit delta (Delta-coat protein) (Delta-COP) (Archain).

COPD_HUMAN
NC score	0.012537 (rank : 211)	θ value	6.88961 (rank : 182)
Query Neighborhood Hits	219	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	P48444, Q52M80	Gene names	ARCN1, COPD
Domain Architecture
Description	Coatomer subunit delta (Delta-coat protein) (Delta-COP) (Archain).

ADDB_MOUSE
NC score	0.011313 (rank : 212)	θ value	6.88961 (rank : 177)
Query Neighborhood Hits	219	Target Neighborhood Hits	574	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

ELF4_MOUSE
NC score	0.011079 (rank : 213)	θ value	6.88961 (rank : 185)
Query Neighborhood Hits	219	Target Neighborhood Hits	191	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z2U4	Gene names	Elf4, Mef
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-4 (E74-like factor 4) (Myeloid Elf-1-like factor).

PTPRN_MOUSE
NC score	0.010759 (rank : 214)	θ value	0.47712 (rank : 111)
Query Neighborhood Hits	219	Target Neighborhood Hits	240	Shared Neighborhood Hits	8
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

K1H1_MOUSE
NC score	0.010701 (rank : 215)	θ value	8.99809 (rank : 204)
Query Neighborhood Hits	219	Target Neighborhood Hits	450	Shared Neighborhood Hits	54
SwissProt Accessions	Q61765	Gene names	Krtha1, Hka1, Krt1-1
Domain Architecture
Description	Keratin, type I cuticular Ha1 (Hair keratin, type I Ha1) (HKA-1).

MTMR5_HUMAN
NC score	0.010518 (rank : 216)	θ value	8.99809 (rank : 208)
Query Neighborhood Hits	219	Target Neighborhood Hits	141	Shared Neighborhood Hits	9
SwissProt Accessions	O95248, O60228, Q5JXD8, Q5PPM2, Q96GR9, Q9UGB8	Gene names	SBF1, MTMR5
Domain Architecture
Description	SET-binding factor 1 (Sbf1) (Myotubularin-related protein 5).

UBP37_HUMAN
NC score	0.010204 (rank : 217)	θ value	6.88961 (rank : 195)
Query Neighborhood Hits	219	Target Neighborhood Hits	208	Shared Neighborhood Hits	22
SwissProt Accessions	Q86T82, Q9HCH8	Gene names	USP37, KIAA1594
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.1.2.15) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37) (Deubiquitinating enzyme 37).

NFAC1_HUMAN
NC score	0.009961 (rank : 218)	θ value	8.99809 (rank : 210)
Query Neighborhood Hits	219	Target Neighborhood Hits	312	Shared Neighborhood Hits	13
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

CEND_HUMAN
NC score	0.009895 (rank : 219)	θ value	8.99809 (rank : 197)
Query Neighborhood Hits	219	Target Neighborhood Hits	84	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N111, Q9NYM6	Gene names	CEND1, BM88
Domain Architecture	No domain graphic available
Description	Cell cycle exit and neuronal differentiation protein 1 (BM88 antigen).

ANK2_HUMAN
NC score	0.009490 (rank : 220)	θ value	8.99809 (rank : 196)
Query Neighborhood Hits	219	Target Neighborhood Hits	1615	Shared Neighborhood Hits	67
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

SPEG_HUMAN
NC score	0.008614 (rank : 221)	θ value	1.06291 (rank : 126)
Query Neighborhood Hits	219	Target Neighborhood Hits	1762	Shared Neighborhood Hits	34
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

AF10_HUMAN
NC score	0.007469 (rank : 222)	θ value	6.88961 (rank : 178)
Query Neighborhood Hits	219	Target Neighborhood Hits	198	Shared Neighborhood Hits	13
SwissProt Accessions	P55197	Gene names	MLLT10, AF10
Domain Architecture
Description	Protein AF-10.

ST5_HUMAN
NC score	0.006150 (rank : 223)	θ value	8.99809 (rank : 216)
Query Neighborhood Hits	219	Target Neighborhood Hits	151	Shared Neighborhood Hits	10
SwissProt Accessions	P78524, P78523, Q16492, Q7KYY2, Q7KZ12, Q8NE12, Q9BQQ6	Gene names	ST5, DENND2B, HTS1
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (HeLa tumor suppression 1) (DENN domain-containing protein 2B).

FARP1_HUMAN
NC score	0.006032 (rank : 224)	θ value	1.81305 (rank : 135)
Query Neighborhood Hits	219	Target Neighborhood Hits	241	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

GCP4_MOUSE
NC score	0.005596 (rank : 225)	θ value	8.99809 (rank : 202)
Query Neighborhood Hits	219	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D4F8	Gene names	Tubgcp4, D2Ertd435e, Gcp4
Domain Architecture
Description	Gamma-tubulin complex component 4 (GCP-4).

DAZP1_MOUSE
NC score	0.005103 (rank : 226)	θ value	6.88961 (rank : 184)
Query Neighborhood Hits	219	Target Neighborhood Hits	313	Shared Neighborhood Hits	13
SwissProt Accessions	Q9JII5	Gene names	Dazap1
Domain Architecture
Description	DAZ-associated protein 1 (Deleted in azoospermia-associated protein 1).

SPEG_MOUSE
NC score	0.003791 (rank : 227)	θ value	3.0926 (rank : 156)
Query Neighborhood Hits	219	Target Neighborhood Hits	1959	Shared Neighborhood Hits	40
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

TITIN_HUMAN
NC score	0.003099 (rank : 228)	θ value	5.27518 (rank : 175)
Query Neighborhood Hits	219	Target Neighborhood Hits	2923	Shared Neighborhood Hits	85
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

DNMBP_HUMAN
NC score	0.001980 (rank : 229)	θ value	8.99809 (rank : 199)
Query Neighborhood Hits	219	Target Neighborhood Hits	413	Shared Neighborhood Hits	20
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

FES_MOUSE
NC score	-0.000113 (rank : 230)	θ value	1.81305 (rank : 136)
Query Neighborhood Hits	219	Target Neighborhood Hits	980	Shared Neighborhood Hits	32
SwissProt Accessions	P16879, Q62122	Gene names	Fes, Fps
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

NR1D2_HUMAN
NC score	-0.000418 (rank : 231)	θ value	8.99809 (rank : 211)
Query Neighborhood Hits	219	Target Neighborhood Hits	115	Shared Neighborhood Hits	2
SwissProt Accessions	Q14995, O00402, Q86XD4	Gene names	NR1D2
Domain Architecture
Description	Orphan nuclear receptor NR1D2 (Rev-erb-beta) (EAR-1R) (Orphan nuclear hormone receptor BD73).

SUHW4_HUMAN
NC score	-0.000860 (rank : 232)	θ value	5.27518 (rank : 174)
Query Neighborhood Hits	219	Target Neighborhood Hits	860	Shared Neighborhood Hits	16
SwissProt Accessions	Q6N043, Q6MZM6, Q6N085, Q9H0U5, Q9HCI8, Q9NXS0	Gene names	SUHW4, KIAA1584
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 4.

MARK2_HUMAN
NC score	-0.001044 (rank : 233)	θ value	6.88961 (rank : 191)
Query Neighborhood Hits	219	Target Neighborhood Hits	1056	Shared Neighborhood Hits	25
SwissProt Accessions	Q7KZI7, Q15449, Q15524, Q5XGA3, Q68A18, Q96HB3, Q96RG0	Gene names	MARK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog).

ZIM2_HUMAN
NC score	-0.006615 (rank : 234)	θ value	8.99809 (rank : 219)
Query Neighborhood Hits	219	Target Neighborhood Hits	718	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NZV7	Gene names	ZIM2
Domain Architecture
Description	Zinc finger imprinted 2.