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Network neighborhood for query Sequence : TITIN_HUMAN

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TITIN_HUMAN
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

HMCN1_HUMAN
θ value	0 (rank : 1)	NC score	0.418776 (rank : 921)
Query Neighborhood Hits	2923	Target Neighborhood Hits	983	Shared Neighborhood Hits	538
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

OBSCN_HUMAN
θ value	0 (rank : 2)	NC score	0.903999 (rank : 2)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1931	Shared Neighborhood Hits	1346
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

TITIN_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	2923	Target Neighborhood Hits	2923	Shared Neighborhood Hits	2923
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

PGBM_HUMAN
θ value	6.00439e-129 (rank : 4)	NC score	0.416093 (rank : 925)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1113	Shared Neighborhood Hits	526
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

MYLK_HUMAN
θ value	2.62879e-100 (rank : 5)	NC score	0.902152 (rank : 3)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1328	Shared Neighborhood Hits	1146
SwissProt Accessions	Q15746, O95796, O95797, O95798, O95799, Q14844, Q16794, Q5MY99, Q5MYA0, Q7Z4J0, Q9C0L5, Q9UBG5, Q9UIT9	Gene names	MYLK, MLCK
Domain Architecture
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

MYLK_MOUSE
θ value	5.85632e-100 (rank : 6)	NC score	0.901136 (rank : 4)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1489	Shared Neighborhood Hits	1223
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

MYPC3_MOUSE
θ value	8.20983e-86 (rank : 7)	NC score	0.499702 (rank : 840)
Query Neighborhood Hits	2923	Target Neighborhood Hits	310	Shared Neighborhood Hits	295
SwissProt Accessions	O70468, O88997	Gene names	Mybpc3
Domain Architecture
Description	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform).

PGBM_MOUSE
θ value	9.39325e-82 (rank : 8)	NC score	0.401515 (rank : 946)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1073	Shared Neighborhood Hits	512
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

OBSL1_HUMAN
θ value	1.49966e-79 (rank : 9)	NC score	0.548242 (rank : 762)
Query Neighborhood Hits	2923	Target Neighborhood Hits	354	Shared Neighborhood Hits	321
SwissProt Accessions	O75147, Q96IW3	Gene names	OBSL1, KIAA0657
Domain Architecture	No domain graphic available
Description	Obscurin-like protein 1 precursor.

MYPC2_MOUSE
θ value	4.99229e-75 (rank : 10)	NC score	0.503310 (rank : 839)
Query Neighborhood Hits	2923	Target Neighborhood Hits	297	Shared Neighborhood Hits	282
SwissProt Accessions	Q5XKE0, Q8C109, Q8K2V0	Gene names	Mybpc2
Domain Architecture	No domain graphic available
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

MYPC2_HUMAN
θ value	9.41505e-74 (rank : 11)	NC score	0.505363 (rank : 837)
Query Neighborhood Hits	2923	Target Neighborhood Hits	316	Shared Neighborhood Hits	303
SwissProt Accessions	Q14324	Gene names	MYBPC2, MYBPCF
Domain Architecture
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

MYPC1_HUMAN
θ value	1.22964e-73 (rank : 12)	NC score	0.510480 (rank : 834)
Query Neighborhood Hits	2923	Target Neighborhood Hits	303	Shared Neighborhood Hits	289
SwissProt Accessions	Q00872, Q15497	Gene names	MYBPC1, MYBPCS
Domain Architecture
Description	Myosin-binding protein C, slow-type (Slow MyBP-C) (C-protein, skeletal muscle slow isoform).

MYPC3_HUMAN
θ value	7.45998e-71 (rank : 13)	NC score	0.499067 (rank : 841)
Query Neighborhood Hits	2923	Target Neighborhood Hits	318	Shared Neighborhood Hits	300
SwissProt Accessions	Q14896, Q16410, Q6R2F7, Q9UE27, Q9UM53	Gene names	MYBPC3
Domain Architecture
Description	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform).

MYOM2_HUMAN
θ value	1.27248e-70 (rank : 14)	NC score	0.515430 (rank : 824)
Query Neighborhood Hits	2923	Target Neighborhood Hits	341	Shared Neighborhood Hits	324
SwissProt Accessions	P54296	Gene names	MYOM2
Domain Architecture
Description	Myomesin-2 (M-protein) (165 kDa titin-associated protein) (165 kDa connectin-associated protein).

MYOM1_HUMAN
θ value	1.40689e-69 (rank : 15)	NC score	0.513569 (rank : 827)
Query Neighborhood Hits	2923	Target Neighborhood Hits	405	Shared Neighborhood Hits	374
SwissProt Accessions	P52179	Gene names	MYOM1
Domain Architecture
Description	Myomesin-1 (190 kDa titin-associated protein) (190 kDa connectin- associated protein).

MYOM1_MOUSE
θ value	2.93355e-67 (rank : 16)	NC score	0.515829 (rank : 823)
Query Neighborhood Hits	2923	Target Neighborhood Hits	415	Shared Neighborhood Hits	381
SwissProt Accessions	Q62234	Gene names	Myom1
Domain Architecture
Description	Myomesin-1 (Skelemin).

DSCAM_HUMAN
θ value	1.11475e-66 (rank : 17)	NC score	0.573024 (rank : 702)
Query Neighborhood Hits	2923	Target Neighborhood Hits	524	Shared Neighborhood Hits	473
SwissProt Accessions	O60469, O60468	Gene names	DSCAM
Domain Architecture
Description	Down syndrome cell adhesion molecule precursor (CHD2).

DSCL1_HUMAN
θ value	1.96772e-63 (rank : 18)	NC score	0.575410 (rank : 696)
Query Neighborhood Hits	2923	Target Neighborhood Hits	589	Shared Neighborhood Hits	502
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

SDK2_MOUSE
θ value	1.55911e-60 (rank : 19)	NC score	0.556003 (rank : 737)
Query Neighborhood Hits	2923	Target Neighborhood Hits	480	Shared Neighborhood Hits	443
SwissProt Accessions	Q6V4S5, Q3TTK1, Q5U5W7, Q6ZPP2	Gene names	Sdk2, Kiaa1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

DUET_HUMAN
θ value	2.03627e-60 (rank : 20)	NC score	0.824743 (rank : 7)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1220	Shared Neighborhood Hits	1026
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

MYPN_HUMAN
θ value	5.54529e-58 (rank : 21)	NC score	0.522430 (rank : 816)
Query Neighborhood Hits	2923	Target Neighborhood Hits	418	Shared Neighborhood Hits	355
SwissProt Accessions	Q86TC9, Q5VV35, Q5VV36, Q86T37, Q8N3L4, Q96K90, Q96KF5	Gene names	MYPN, MYOP
Domain Architecture	No domain graphic available
Description	Myopalladin (145 kDa sarcomeric protein).

MYPN_MOUSE
θ value	2.7521e-57 (rank : 22)	NC score	0.518493 (rank : 820)
Query Neighborhood Hits	2923	Target Neighborhood Hits	421	Shared Neighborhood Hits	338
SwissProt Accessions	Q5DTJ9, Q7TPW5, Q8BZ76	Gene names	Mypn, Kiaa4170
Domain Architecture	No domain graphic available
Description	Myopalladin.

MYLK2_HUMAN
θ value	3.0428e-56 (rank : 23)	NC score	0.759385 (rank : 14)
Query Neighborhood Hits	2923	Target Neighborhood Hits	920	Shared Neighborhood Hits	830
SwissProt Accessions	Q9H1R3, Q96I84	Gene names	MYLK2
Domain Architecture
Description	Myosin light chain kinase 2, skeletal/cardiac muscle (EC 2.7.11.18) (MLCK2).

SDK2_HUMAN
θ value	6.77864e-56 (rank : 24)	NC score	0.557133 (rank : 729)
Query Neighborhood Hits	2923	Target Neighborhood Hits	495	Shared Neighborhood Hits	456
SwissProt Accessions	Q58EX2, Q86VY3, Q9NTD2, Q9NVB3, Q9P214	Gene names	SDK2, KIAA1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

SDK1_MOUSE
θ value	3.36421e-55 (rank : 25)	NC score	0.554658 (rank : 744)
Query Neighborhood Hits	2923	Target Neighborhood Hits	495	Shared Neighborhood Hits	444
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

DAPK3_MOUSE
θ value	5.73848e-55 (rank : 26)	NC score	0.759809 (rank : 12)
Query Neighborhood Hits	2923	Target Neighborhood Hits	843	Shared Neighborhood Hits	792
SwissProt Accessions	O54784	Gene names	Dapk3, Zipk
Domain Architecture
Description	Death-associated protein kinase 3 (EC 2.7.11.1) (DAP kinase 3) (DAP- like kinase) (Dlk) (ZIP-kinase).

DAPK3_HUMAN
θ value	7.49467e-55 (rank : 27)	NC score	0.759705 (rank : 13)
Query Neighborhood Hits	2923	Target Neighborhood Hits	945	Shared Neighborhood Hits	848
SwissProt Accessions	O43293	Gene names	DAPK3, ZIPK
Domain Architecture
Description	Death-associated protein kinase 3 (EC 2.7.11.1) (DAP kinase 3) (DAP- like kinase) (Dlk) (ZIP-kinase).

DAPK1_MOUSE
θ value	1.66964e-54 (rank : 28)	NC score	0.682034 (rank : 450)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1138	Shared Neighborhood Hits	827
SwissProt Accessions	Q80YE7, Q80YE6, Q8R341, Q8VDN6, Q9CSD4, Q9JJP7	Gene names	Dapk1
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

DAPK2_HUMAN
θ value	2.18062e-54 (rank : 29)	NC score	0.761178 (rank : 9)
Query Neighborhood Hits	2923	Target Neighborhood Hits	832	Shared Neighborhood Hits	787
SwissProt Accessions	Q9UIK4, O75892	Gene names	DAPK2
Domain Architecture
Description	Death-associated protein kinase 2 (EC 2.7.11.1) (DAP kinase 2) (DAP- kinase-related protein 1) (DRP-1).

SPEG_MOUSE
θ value	2.18062e-54 (rank : 30)	NC score	0.889508 (rank : 5)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1959	Shared Neighborhood Hits	1341
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

DAPK2_MOUSE
θ value	6.34462e-54 (rank : 31)	NC score	0.760354 (rank : 10)
Query Neighborhood Hits	2923	Target Neighborhood Hits	834	Shared Neighborhood Hits	789
SwissProt Accessions	Q8VDF3, O88861, Q9QYM4	Gene names	Dapk2
Domain Architecture
Description	Death-associated protein kinase 2 (EC 2.7.11.1) (DAP kinase 2) (DAP- kinase-related protein 1) (DRP-1).

SDK1_HUMAN
θ value	8.28633e-54 (rank : 32)	NC score	0.556173 (rank : 735)
Query Neighborhood Hits	2923	Target Neighborhood Hits	511	Shared Neighborhood Hits	449
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

DAPK1_HUMAN
θ value	1.84601e-53 (rank : 33)	NC score	0.685735 (rank : 423)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1130	Shared Neighborhood Hits	827
SwissProt Accessions	P53355, Q9BTL8	Gene names	DAPK1, DAPK
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

SN_MOUSE
θ value	4.11246e-53 (rank : 34)	NC score	0.482356 (rank : 867)
Query Neighborhood Hits	2923	Target Neighborhood Hits	416	Shared Neighborhood Hits	364
SwissProt Accessions	Q62230, O55216, Q62228, Q62229	Gene names	Sn, Sa
Domain Architecture
Description	Sialoadhesin precursor (Sialic acid-binding Ig-like lectin-1) (Siglec- 1) (Sheep erythrocyte receptor) (SER) (CD169 antigen).

SPEG_HUMAN
θ value	7.75577e-52 (rank : 35)	NC score	0.889460 (rank : 6)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1762	Shared Neighborhood Hits	1282
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

ST17A_HUMAN
θ value	2.1121e-49 (rank : 36)	NC score	0.759891 (rank : 11)
Query Neighborhood Hits	2923	Target Neighborhood Hits	843	Shared Neighborhood Hits	790
SwissProt Accessions	Q9UEE5, Q8IVC8	Gene names	STK17A, DRAK1
Domain Architecture
Description	Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 1).

SN_HUMAN
θ value	4.70527e-49 (rank : 37)	NC score	0.478313 (rank : 876)
Query Neighborhood Hits	2923	Target Neighborhood Hits	434	Shared Neighborhood Hits	377
SwissProt Accessions	Q9BZZ2, Q96DL4, Q9GZS5, Q9H1H6, Q9H1H7, Q9H7L7	Gene names	SN
Domain Architecture
Description	Sialoadhesin precursor (Sialic acid-binding Ig-like lectin-1) (Siglec- 1) (CD169 antigen).

ST17B_HUMAN
θ value	6.35935e-46 (rank : 38)	NC score	0.757065 (rank : 15)
Query Neighborhood Hits	2923	Target Neighborhood Hits	833	Shared Neighborhood Hits	784
SwissProt Accessions	O94768	Gene names	STK17B, DRAK2
Domain Architecture
Description	Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 2).

ST17B_MOUSE
θ value	1.08474e-45 (rank : 39)	NC score	0.756993 (rank : 16)
Query Neighborhood Hits	2923	Target Neighborhood Hits	838	Shared Neighborhood Hits	788
SwissProt Accessions	Q8BG48, Q3TNG7, Q8BLV9, Q923E7	Gene names	Stk17b, Drak2
Domain Architecture
Description	Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 2).

ROBO3_HUMAN
θ value	2.95404e-43 (rank : 40)	NC score	0.560646 (rank : 723)
Query Neighborhood Hits	2923	Target Neighborhood Hits	570	Shared Neighborhood Hits	479
SwissProt Accessions	Q96MS0	Gene names	ROBO3
Domain Architecture
Description	Roundabout homolog 3 precursor (Roundabout-like protein 3).

CNTN4_MOUSE
θ value	1.12253e-42 (rank : 41)	NC score	0.534138 (rank : 795)
Query Neighborhood Hits	2923	Target Neighborhood Hits	445	Shared Neighborhood Hits	422
SwissProt Accessions	Q69Z26, Q8BRT6, Q8CBD3	Gene names	Cntn4, Kiaa3024
Domain Architecture	No domain graphic available
Description	Contactin-4 precursor (Brain-derived immunoglobulin superfamily protein 2) (BIG-2).

NCAM2_HUMAN
θ value	1.46607e-42 (rank : 42)	NC score	0.554628 (rank : 745)
Query Neighborhood Hits	2923	Target Neighborhood Hits	441	Shared Neighborhood Hits	422
SwissProt Accessions	O15394	Gene names	NCAM2, NCAM21
Domain Architecture
Description	Neural cell adhesion molecule 2 precursor (N-CAM 2).

ROBO1_HUMAN
θ value	1.91475e-42 (rank : 43)	NC score	0.551848 (rank : 753)
Query Neighborhood Hits	2923	Target Neighborhood Hits	529	Shared Neighborhood Hits	461
SwissProt Accessions	Q9Y6N7, Q7Z300, Q9BUS7	Gene names	ROBO1, DUTT1
Domain Architecture
Description	Roundabout homolog 1 precursor (H-Robo-1) (Deleted in U twenty twenty).

FNDC3_MOUSE
θ value	2.50074e-42 (rank : 44)	NC score	0.414069 (rank : 932)
Query Neighborhood Hits	2923	Target Neighborhood Hits	207	Shared Neighborhood Hits	183
SwissProt Accessions	Q8BX90, Q2VEY7, Q6ZQ15, Q811D3, Q8BTM3	Gene names	Fndc3a, D14Ertd453e, Fndc3, Kiaa0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

KCC4_HUMAN
θ value	3.26607e-42 (rank : 45)	NC score	0.752377 (rank : 24)
Query Neighborhood Hits	2923	Target Neighborhood Hits	841	Shared Neighborhood Hits	784
SwissProt Accessions	Q16566	Gene names	CAMK4
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type IV (EC 2.7.11.17) (CAM kinase-GR) (CaMK IV).

KCC4_MOUSE
θ value	3.26607e-42 (rank : 46)	NC score	0.752647 (rank : 21)
Query Neighborhood Hits	2923	Target Neighborhood Hits	899	Shared Neighborhood Hits	823
SwissProt Accessions	P08414, Q61381	Gene names	Camk4
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type IV (EC 2.7.11.17) (CAM kinase-GR) (CaMK IV).

NCAM2_MOUSE
θ value	4.2656e-42 (rank : 47)	NC score	0.560598 (rank : 724)
Query Neighborhood Hits	2923	Target Neighborhood Hits	472	Shared Neighborhood Hits	446
SwissProt Accessions	O35136, O35962	Gene names	Ncam2, Ocam, Rncam
Domain Architecture
Description	Neural cell adhesion molecule 2 precursor (N-CAM 2) (RB-8 neural cell adhesion molecule) (R4B12).

ROBO2_MOUSE
θ value	4.2656e-42 (rank : 48)	NC score	0.556889 (rank : 731)
Query Neighborhood Hits	2923	Target Neighborhood Hits	504	Shared Neighborhood Hits	461
SwissProt Accessions	Q7TPD3, Q8BJ59	Gene names	Robo2, Kiaa1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

ROBO3_MOUSE
θ value	5.57106e-42 (rank : 49)	NC score	0.553214 (rank : 749)
Query Neighborhood Hits	2923	Target Neighborhood Hits	524	Shared Neighborhood Hits	457
SwissProt Accessions	Q9Z2I4	Gene names	Robo3, Rbig1
Domain Architecture
Description	Roundabout homolog 3 precursor (Retinoblastoma-inhibiting gene 1) (Rig-1).

ROBO1_MOUSE
θ value	7.27602e-42 (rank : 50)	NC score	0.555008 (rank : 743)
Query Neighborhood Hits	2923	Target Neighborhood Hits	559	Shared Neighborhood Hits	483
SwissProt Accessions	O89026	Gene names	Robo1, Dutt1
Domain Architecture
Description	Roundabout homolog 1 precursor.

ROBO2_HUMAN
θ value	7.27602e-42 (rank : 51)	NC score	0.556466 (rank : 732)
Query Neighborhood Hits	2923	Target Neighborhood Hits	479	Shared Neighborhood Hits	446
SwissProt Accessions	Q9HCK4, O43608	Gene names	ROBO2, KIAA1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

CNTN4_HUMAN
θ value	1.62093e-41 (rank : 52)	NC score	0.533376 (rank : 800)
Query Neighborhood Hits	2923	Target Neighborhood Hits	449	Shared Neighborhood Hits	425
SwissProt Accessions	Q8IWV2, Q8IX14, Q8TC35	Gene names	CNTN4
Domain Architecture	No domain graphic available
Description	Contactin-4 precursor (Brain-derived immunoglobulin superfamily protein 2) (BIG-2).

FNDC3_HUMAN
θ value	2.76489e-41 (rank : 53)	NC score	0.410101 (rank : 937)
Query Neighborhood Hits	2923	Target Neighborhood Hits	196	Shared Neighborhood Hits	183
SwissProt Accessions	Q9Y2H6, Q5JVF9, Q6EVH3, Q6N020, Q6P9D5, Q9H1W1	Gene names	FNDC3A, FNDC3, KIAA0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

KPSH1_HUMAN
θ value	1.79215e-40 (rank : 54)	NC score	0.752839 (rank : 20)
Query Neighborhood Hits	2923	Target Neighborhood Hits	842	Shared Neighborhood Hits	787
SwissProt Accessions	P11801, Q9NY19	Gene names	PSKH1
Domain Architecture
Description	Serine/threonine-protein kinase H1 (EC 2.7.11.1) (PSK-H1).

CNTN6_MOUSE
θ value	3.05695e-40 (rank : 55)	NC score	0.524566 (rank : 806)
Query Neighborhood Hits	2923	Target Neighborhood Hits	429	Shared Neighborhood Hits	411
SwissProt Accessions	Q9JMB8, Q8C6X1	Gene names	Cntn6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (mNB-3).

PTPRD_HUMAN
θ value	3.05695e-40 (rank : 56)	NC score	0.419731 (rank : 919)
Query Neighborhood Hits	2923	Target Neighborhood Hits	485	Shared Neighborhood Hits	400
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

KPSH1_MOUSE
θ value	5.21438e-40 (rank : 57)	NC score	0.752522 (rank : 22)
Query Neighborhood Hits	2923	Target Neighborhood Hits	839	Shared Neighborhood Hits	787
SwissProt Accessions	Q91YA2, Q3U3V3	Gene names	Pskh1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase H1 (EC 2.7.11.1) (PSK-H1).

MYBPH_MOUSE
θ value	1.51715e-39 (rank : 58)	NC score	0.459577 (rank : 894)
Query Neighborhood Hits	2923	Target Neighborhood Hits	290	Shared Neighborhood Hits	260
SwissProt Accessions	P70402	Gene names	Mybph
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

CNTN5_HUMAN
θ value	4.41421e-39 (rank : 59)	NC score	0.538283 (rank : 787)
Query Neighborhood Hits	2923	Target Neighborhood Hits	446	Shared Neighborhood Hits	433
SwissProt Accessions	O94779, O94780	Gene names	CNTN5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2) (hNB-2).

FINC_MOUSE
θ value	7.52953e-39 (rank : 60)	NC score	0.329248 (rank : 989)
Query Neighborhood Hits	2923	Target Neighborhood Hits	309	Shared Neighborhood Hits	215
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

PTK7_HUMAN
θ value	1.28434e-38 (rank : 61)	NC score	0.743487 (rank : 49)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1103	Shared Neighborhood Hits	1028
SwissProt Accessions	Q13308, Q13417	Gene names	PTK7, CCK4
Domain Architecture
Description	Tyrosine-protein kinase-like 7 precursor (Colon carcinoma kinase 4) (CCK-4).

KCC1D_HUMAN
θ value	2.19075e-38 (rank : 62)	NC score	0.752199 (rank : 27)
Query Neighborhood Hits	2923	Target Neighborhood Hits	846	Shared Neighborhood Hits	788
SwissProt Accessions	Q8IU85, Q9HD31	Gene names	CAMK1D
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK).

KCC1D_MOUSE
θ value	2.19075e-38 (rank : 63)	NC score	0.752329 (rank : 26)
Query Neighborhood Hits	2923	Target Neighborhood Hits	847	Shared Neighborhood Hits	789
SwissProt Accessions	Q8BW96, Q3U450, Q80W64, Q8BWI7	Gene names	Camk1d
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK) (mCKLiK).

CNTN5_MOUSE
θ value	2.86122e-38 (rank : 64)	NC score	0.533634 (rank : 798)
Query Neighborhood Hits	2923	Target Neighborhood Hits	434	Shared Neighborhood Hits	418
SwissProt Accessions	P68500	Gene names	Cntn5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2).

KCC1A_MOUSE
θ value	3.73686e-38 (rank : 65)	NC score	0.753507 (rank : 18)
Query Neighborhood Hits	2923	Target Neighborhood Hits	845	Shared Neighborhood Hits	793
SwissProt Accessions	Q91YS8	Gene names	Camk1
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha).

CNTN6_HUMAN
θ value	6.37413e-38 (rank : 66)	NC score	0.522938 (rank : 813)
Query Neighborhood Hits	2923	Target Neighborhood Hits	422	Shared Neighborhood Hits	409
SwissProt Accessions	Q9UQ52	Gene names	CNTN6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (hNB-3).

KCC1A_HUMAN
θ value	1.08726e-37 (rank : 67)	NC score	0.753359 (rank : 19)
Query Neighborhood Hits	2923	Target Neighborhood Hits	846	Shared Neighborhood Hits	793
SwissProt Accessions	Q14012	Gene names	CAMK1
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha).

MYBPH_HUMAN
θ value	1.08726e-37 (rank : 68)	NC score	0.458358 (rank : 896)
Query Neighborhood Hits	2923	Target Neighborhood Hits	256	Shared Neighborhood Hits	249
SwissProt Accessions	Q13203, Q16886, Q86YC5	Gene names	MYBPH
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

KCC2G_HUMAN
θ value	3.16345e-37 (rank : 69)	NC score	0.750306 (rank : 33)
Query Neighborhood Hits	2923	Target Neighborhood Hits	841	Shared Neighborhood Hits	787
SwissProt Accessions	Q13555, O15378, Q13556, Q5SQZ4	Gene names	CAMK2G
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase type II gamma chain (EC 2.7.11.17) (CaM-kinase II gamma chain) (CaM kinase II gamma subunit) (CaMK-II subunit gamma).

KCC2G_MOUSE
θ value	3.16345e-37 (rank : 70)	NC score	0.750330 (rank : 32)
Query Neighborhood Hits	2923	Target Neighborhood Hits	838	Shared Neighborhood Hits	788
SwissProt Accessions	Q923T9, Q3U3H3, Q8VED3	Gene names	Camk2g
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type II gamma chain (EC 2.7.11.17) (CaM-kinase II gamma chain) (CaM kinase II gamma subunit) (CaMK-II subunit gamma).

KCC2D_HUMAN
θ value	7.04741e-37 (rank : 71)	NC score	0.749563 (rank : 39)
Query Neighborhood Hits	2923	Target Neighborhood Hits	830	Shared Neighborhood Hits	786
SwissProt Accessions	Q13557, Q9UGH6, Q9UQE9	Gene names	CAMK2D
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type II delta chain (EC 2.7.11.17) (CaM-kinase II delta chain) (CaM kinase II subunit delta) (CaMK-II subunit delta).

PTPRD_MOUSE
θ value	7.04741e-37 (rank : 72)	NC score	0.428986 (rank : 910)
Query Neighborhood Hits	2923	Target Neighborhood Hits	491	Shared Neighborhood Hits	410
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

CNTN3_MOUSE
θ value	9.20422e-37 (rank : 73)	NC score	0.529490 (rank : 804)
Query Neighborhood Hits	2923	Target Neighborhood Hits	447	Shared Neighborhood Hits	430
SwissProt Accessions	Q07409	Gene names	Cntn3, Pang, Pcs
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

KPSH2_HUMAN
θ value	1.20211e-36 (rank : 74)	NC score	0.754003 (rank : 17)
Query Neighborhood Hits	2923	Target Neighborhood Hits	822	Shared Neighborhood Hits	783
SwissProt Accessions	Q96QS6	Gene names	PSKH2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase H2 (EC 2.7.11.1) (PSK-H2).

NEO1_HUMAN
θ value	1.20211e-36 (rank : 75)	NC score	0.555356 (rank : 740)
Query Neighborhood Hits	2923	Target Neighborhood Hits	530	Shared Neighborhood Hits	460
SwissProt Accessions	Q92859, O00340	Gene names	NEO1, NGN
Domain Architecture
Description	Neogenin precursor.

PRAX_HUMAN
θ value	1.20211e-36 (rank : 76)	NC score	0.128730 (rank : 1160)
Query Neighborhood Hits	2923	Target Neighborhood Hits	215	Shared Neighborhood Hits	110
SwissProt Accessions	Q9BXM0, Q9BXL9, Q9HCF2	Gene names	PRX, KIAA1620
Domain Architecture
Description	Periaxin.

KCC2A_HUMAN
θ value	3.4976e-36 (rank : 77)	NC score	0.749931 (rank : 36)
Query Neighborhood Hits	2923	Target Neighborhood Hits	830	Shared Neighborhood Hits	783
SwissProt Accessions	Q9UQM7, Q9Y352	Gene names	CAMK2A
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type II alpha chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II subunit alpha).

CNTN3_HUMAN
θ value	4.568e-36 (rank : 78)	NC score	0.534253 (rank : 794)
Query Neighborhood Hits	2923	Target Neighborhood Hits	455	Shared Neighborhood Hits	434
SwissProt Accessions	Q9P232, Q9H039	Gene names	CNTN3, KIAA1496, PANG
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

KCC2A_MOUSE
θ value	4.568e-36 (rank : 79)	NC score	0.749711 (rank : 38)
Query Neighborhood Hits	2923	Target Neighborhood Hits	829	Shared Neighborhood Hits	783
SwissProt Accessions	P11798, Q61284	Gene names	Camk2a
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type II alpha chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II subunit alpha).

L1CAM_HUMAN
θ value	4.568e-36 (rank : 80)	NC score	0.533828 (rank : 797)
Query Neighborhood Hits	2923	Target Neighborhood Hits	457	Shared Neighborhood Hits	432
SwissProt Accessions	P32004, Q8TA87	Gene names	L1CAM, CAML1, MIC5
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

TRIO_HUMAN
θ value	5.96599e-36 (rank : 81)	NC score	0.776941 (rank : 8)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1580	Shared Neighborhood Hits	1212
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

CNTN2_MOUSE
θ value	1.01765e-35 (rank : 82)	NC score	0.538941 (rank : 784)
Query Neighborhood Hits	2923	Target Neighborhood Hits	450	Shared Neighborhood Hits	428
SwissProt Accessions	Q61330, Q6NZJ4, Q7TSJ5	Gene names	Cntn2, Tax
Domain Architecture	No domain graphic available
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

NRCAM_HUMAN
θ value	1.01765e-35 (rank : 83)	NC score	0.539377 (rank : 779)
Query Neighborhood Hits	2923	Target Neighborhood Hits	439	Shared Neighborhood Hits	414
SwissProt Accessions	Q92823, O15051, O15179, Q9UHI3, Q9UHI4	Gene names	NRCAM, KIAA0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (hBravo).

DCAK3_HUMAN
θ value	6.59618e-35 (rank : 84)	NC score	0.751028 (rank : 28)
Query Neighborhood Hits	2923	Target Neighborhood Hits	888	Shared Neighborhood Hits	812
SwissProt Accessions	Q9C098	Gene names	DCAMKL3, KIAA1765
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL3 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 3).

CSKP_HUMAN
θ value	8.61488e-35 (rank : 85)	NC score	0.709405 (rank : 265)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1022	Shared Neighborhood Hits	808
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

CSKP_MOUSE
θ value	8.61488e-35 (rank : 86)	NC score	0.711306 (rank : 243)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1027	Shared Neighborhood Hits	807
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

KCC1B_MOUSE
θ value	8.61488e-35 (rank : 87)	NC score	0.752381 (rank : 23)
Query Neighborhood Hits	2923	Target Neighborhood Hits	842	Shared Neighborhood Hits	789
SwissProt Accessions	Q9QYK9, Q80W07	Gene names	Pnck
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase type 1B (EC 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase homolog).

NEO1_MOUSE
θ value	8.61488e-35 (rank : 88)	NC score	0.553631 (rank : 748)
Query Neighborhood Hits	2923	Target Neighborhood Hits	523	Shared Neighborhood Hits	461
SwissProt Accessions	P97798	Gene names	Neo1, Ngn
Domain Architecture
Description	Neogenin precursor.

KCC2B_HUMAN
θ value	1.12514e-34 (rank : 89)	NC score	0.749799 (rank : 37)
Query Neighborhood Hits	2923	Target Neighborhood Hits	866	Shared Neighborhood Hits	800
SwissProt Accessions	Q13554, O95437, O95438, O95599, Q9UGH7, Q9UGH8, Q9UGH9, Q9UNX0, Q9UNX7, Q9UP00, Q9Y5N4, Q9Y6F4	Gene names	CAMK2B, CAM2, CAMKB
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type II beta chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II subunit beta) (CaMK-II subunit beta).

KCC2B_MOUSE
θ value	1.12514e-34 (rank : 90)	NC score	0.747648 (rank : 41)
Query Neighborhood Hits	2923	Target Neighborhood Hits	841	Shared Neighborhood Hits	783
SwissProt Accessions	P28652, Q5SVH9	Gene names	Camk2b, Camk2d
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type II beta chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II subunit beta) (CaMK-II subunit beta).

NCA11_HUMAN
θ value	1.12514e-34 (rank : 91)	NC score	0.539056 (rank : 783)
Query Neighborhood Hits	2923	Target Neighborhood Hits	443	Shared Neighborhood Hits	413
SwissProt Accessions	P13591, Q15829, Q16180	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 140 kDa isoform precursor (N-CAM 140) (NCAM-140) (CD56 antigen).

NCA12_HUMAN
θ value	1.12514e-34 (rank : 92)	NC score	0.536242 (rank : 791)
Query Neighborhood Hits	2923	Target Neighborhood Hits	437	Shared Neighborhood Hits	408
SwissProt Accessions	P13592, P13593	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120) (CD56 antigen).

PHKG1_HUMAN
θ value	1.9192e-34 (rank : 93)	NC score	0.741880 (rank : 57)
Query Neighborhood Hits	2923	Target Neighborhood Hits	838	Shared Neighborhood Hits	781
SwissProt Accessions	Q16816	Gene names	PHKG1, PHKG
Domain Architecture
Description	Phosphorylase b kinase gamma catalytic chain, skeletal muscle isoform (EC 2.7.11.19) (Phosphorylase kinase subunit gamma 1).

FINC_HUMAN
θ value	3.27365e-34 (rank : 94)	NC score	0.323993 (rank : 994)
Query Neighborhood Hits	2923	Target Neighborhood Hits	302	Shared Neighborhood Hits	217
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

NCA11_MOUSE
θ value	3.27365e-34 (rank : 95)	NC score	0.540786 (rank : 775)
Query Neighborhood Hits	2923	Target Neighborhood Hits	661	Shared Neighborhood Hits	532
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

NCA12_MOUSE
θ value	3.27365e-34 (rank : 96)	NC score	0.533550 (rank : 799)
Query Neighborhood Hits	2923	Target Neighborhood Hits	399	Shared Neighborhood Hits	387
SwissProt Accessions	P13594, Q61950	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120).

CNTN2_HUMAN
θ value	4.27553e-34 (rank : 97)	NC score	0.539226 (rank : 782)
Query Neighborhood Hits	2923	Target Neighborhood Hits	440	Shared Neighborhood Hits	424
SwissProt Accessions	Q02246, P78432	Gene names	CNTN2, TAG1, TAX1
Domain Architecture
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

DCAK2_HUMAN
θ value	4.27553e-34 (rank : 98)	NC score	0.741990 (rank : 56)
Query Neighborhood Hits	2923	Target Neighborhood Hits	862	Shared Neighborhood Hits	794
SwissProt Accessions	Q8N568, Q8N399	Gene names	DCAMKL2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL2 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 2).

KCC1B_HUMAN
θ value	4.27553e-34 (rank : 99)	NC score	0.752336 (rank : 25)
Query Neighborhood Hits	2923	Target Neighborhood Hits	842	Shared Neighborhood Hits	789
SwissProt Accessions	Q6P2M8	Gene names	PNCK
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase type 1B (EC 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase).

KCC1G_HUMAN
θ value	4.27553e-34 (rank : 100)	NC score	0.750442 (rank : 31)
Query Neighborhood Hits	2923	Target Neighborhood Hits	850	Shared Neighborhood Hits	791
SwissProt Accessions	Q96NX5, Q86UH5, Q9Y3J7	Gene names	CAMK1G, VWS1
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase type 1G (EC 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM- KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III).

KCC1G_MOUSE
θ value	4.27553e-34 (rank : 101)	NC score	0.750473 (rank : 30)
Query Neighborhood Hits	2923	Target Neighborhood Hits	851	Shared Neighborhood Hits	790
SwissProt Accessions	Q91VB2	Gene names	Camk1g
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase type 1G (EC 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM- KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III).

PTPRF_HUMAN
θ value	5.584e-34 (rank : 102)	NC score	0.428483 (rank : 911)
Query Neighborhood Hits	2923	Target Neighborhood Hits	489	Shared Neighborhood Hits	418
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

DCAK3_MOUSE
θ value	7.29293e-34 (rank : 103)	NC score	0.750606 (rank : 29)
Query Neighborhood Hits	2923	Target Neighborhood Hits	922	Shared Neighborhood Hits	818
SwissProt Accessions	Q8BWQ5, Q1A748	Gene names	Dcamkl3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL3 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 3) (CLICK-I and II-related) (CLr).

NFASC_HUMAN
θ value	2.12192e-33 (rank : 104)	NC score	0.540589 (rank : 776)
Query Neighborhood Hits	2923	Target Neighborhood Hits	497	Shared Neighborhood Hits	449
SwissProt Accessions	O94856, Q5T2F0, Q5T2F1, Q5T2F2, Q5T2F3, Q5T2F4, Q5T2F5, Q5T2F6, Q5T2F7, Q5T2F9, Q5T2G0, Q5W9F8, Q68DH3, Q6ZQV6, Q7Z3K1, Q96HT1, Q96K50	Gene names	NFASC, KIAA0756
Domain Architecture
Description	Neurofascin precursor.

NRCAM_MOUSE
θ value	2.12192e-33 (rank : 105)	NC score	0.537469 (rank : 788)
Query Neighborhood Hits	2923	Target Neighborhood Hits	432	Shared Neighborhood Hits	399
SwissProt Accessions	Q810U4, Q80U33, Q8BLG8, Q8BX92, Q8BYJ8	Gene names	Nrcam, Kiaa0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (mBravo).

PHKG1_MOUSE
θ value	2.12192e-33 (rank : 106)	NC score	0.742410 (rank : 53)
Query Neighborhood Hits	2923	Target Neighborhood Hits	840	Shared Neighborhood Hits	780
SwissProt Accessions	P07934	Gene names	Phkg1, Phkg
Domain Architecture
Description	Phosphorylase b kinase gamma catalytic chain, skeletal muscle isoform (EC 2.7.11.19) (Phosphorylase kinase subunit gamma 1).

PHKG2_HUMAN
θ value	2.12192e-33 (rank : 107)	NC score	0.743630 (rank : 47)
Query Neighborhood Hits	2923	Target Neighborhood Hits	839	Shared Neighborhood Hits	786
SwissProt Accessions	P15735, P11800	Gene names	PHKG2
Domain Architecture
Description	Phosphorylase b kinase gamma catalytic chain, testis/liver isoform (EC 2.7.11.19) (PHK-gamma-T) (Phosphorylase kinase subunit gamma 2) (PSK-C3).

DCAK2_MOUSE
θ value	4.72714e-33 (rank : 108)	NC score	0.742099 (rank : 55)
Query Neighborhood Hits	2923	Target Neighborhood Hits	858	Shared Neighborhood Hits	793
SwissProt Accessions	Q6PGN3, Q8BUU0, Q8BX25	Gene names	Dcamkl2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL2 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 2).

NFASC_MOUSE
θ value	4.72714e-33 (rank : 109)	NC score	0.539724 (rank : 777)
Query Neighborhood Hits	2923	Target Neighborhood Hits	475	Shared Neighborhood Hits	439
SwissProt Accessions	Q810U3	Gene names	Nfasc
Domain Architecture
Description	Neurofascin precursor.

TENX_HUMAN
θ value	6.17384e-33 (rank : 110)	NC score	0.161443 (rank : 1125)
Query Neighborhood Hits	2923	Target Neighborhood Hits	789	Shared Neighborhood Hits	255
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

CHK2_MOUSE
θ value	8.06329e-33 (rank : 111)	NC score	0.746258 (rank : 43)
Query Neighborhood Hits	2923	Target Neighborhood Hits	860	Shared Neighborhood Hits	787
SwissProt Accessions	Q9Z265	Gene names	Chek2, Chk2, Rad53
Domain Architecture
Description	Serine/threonine-protein kinase Chk2 (EC 2.7.11.1).

L1CAM_MOUSE
θ value	8.06329e-33 (rank : 112)	NC score	0.535137 (rank : 792)
Query Neighborhood Hits	2923	Target Neighborhood Hits	457	Shared Neighborhood Hits	433
SwissProt Accessions	P11627	Gene names	L1cam, Caml1
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

PHKG2_MOUSE
θ value	1.0531e-32 (rank : 113)	NC score	0.744113 (rank : 46)
Query Neighborhood Hits	2923	Target Neighborhood Hits	841	Shared Neighborhood Hits	788
SwissProt Accessions	Q9DB30	Gene names	Phkg2
Domain Architecture
Description	Phosphorylase b kinase gamma catalytic chain, testis/liver isoform (EC 2.7.11.19) (PHK-gamma-T) (Phosphorylase kinase subunit gamma 2).

DCAK1_HUMAN
θ value	2.34606e-32 (rank : 114)	NC score	0.743179 (rank : 50)
Query Neighborhood Hits	2923	Target Neighborhood Hits	877	Shared Neighborhood Hits	798
SwissProt Accessions	O15075	Gene names	DCAMKL1, KIAA0369
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 1).

DCAK1_MOUSE
θ value	2.34606e-32 (rank : 115)	NC score	0.743010 (rank : 51)
Query Neighborhood Hits	2923	Target Neighborhood Hits	867	Shared Neighborhood Hits	791
SwissProt Accessions	Q9JLM8, Q6P207	Gene names	Dcamkl1, Dclk
Domain Architecture
Description	Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 1).

KS6A1_MOUSE
θ value	2.34606e-32 (rank : 116)	NC score	0.736082 (rank : 83)
Query Neighborhood Hits	2923	Target Neighborhood Hits	850	Shared Neighborhood Hits	794
SwissProt Accessions	P18653	Gene names	Rps6ka1, Rsk1
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1) (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (p90S6K) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A).

MKNK2_HUMAN
θ value	6.82597e-32 (rank : 117)	NC score	0.742443 (rank : 52)
Query Neighborhood Hits	2923	Target Neighborhood Hits	821	Shared Neighborhood Hits	773
SwissProt Accessions	Q9HBH9, Q6GPI3, Q9HBH8, Q9UHR0, Q9Y2N6	Gene names	MKNK2, MNK2
Domain Architecture
Description	MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 2) (Mnk2).

MKNK2_MOUSE
θ value	8.91499e-32 (rank : 118)	NC score	0.742114 (rank : 54)
Query Neighborhood Hits	2923	Target Neighborhood Hits	819	Shared Neighborhood Hits	772
SwissProt Accessions	Q8CDB0, O08606, Q75PY0, Q9D893	Gene names	Mknk2, Mnk2
Domain Architecture
Description	MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 2) (Mnk2).

KS6A2_HUMAN
θ value	1.16434e-31 (rank : 119)	NC score	0.734267 (rank : 94)
Query Neighborhood Hits	2923	Target Neighborhood Hits	857	Shared Neighborhood Hits	794
SwissProt Accessions	Q15349, Q15419, Q59GJ3, Q5TI68, Q96J38, Q9UJN5	Gene names	RPS6KA2, RSK3
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1) (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (MAP kinase-activated protein kinase 1c) (MAPKAPK1C).

CHL1_MOUSE
θ value	2.59387e-31 (rank : 120)	NC score	0.516137 (rank : 822)
Query Neighborhood Hits	2923	Target Neighborhood Hits	402	Shared Neighborhood Hits	385
SwissProt Accessions	P70232, Q8BS24, Q8C6W0, Q8C823, Q8VBY7	Gene names	Chl1, Call
Domain Architecture	No domain graphic available
Description	Neural cell adhesion molecule L1-like protein precursor (Cell adhesion molecule with homology to L1CAM) (Close homolog of L1) (Chl1-like protein).

DCC_HUMAN
θ value	2.59387e-31 (rank : 121)	NC score	0.553886 (rank : 747)
Query Neighborhood Hits	2923	Target Neighborhood Hits	583	Shared Neighborhood Hits	498
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

KS6A1_HUMAN
θ value	2.59387e-31 (rank : 122)	NC score	0.733753 (rank : 101)
Query Neighborhood Hits	2923	Target Neighborhood Hits	854	Shared Neighborhood Hits	794
SwissProt Accessions	Q15418, Q5SVM5, Q5SVM8, Q5SVM9, Q96C05, Q9BQK2	Gene names	RPS6KA1, RSK1
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1) (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (p90S6K) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A).

MKNK1_MOUSE
θ value	2.59387e-31 (rank : 123)	NC score	0.737742 (rank : 71)
Query Neighborhood Hits	2923	Target Neighborhood Hits	811	Shared Neighborhood Hits	758
SwissProt Accessions	O08605	Gene names	Mknk1, Mnk1
Domain Architecture
Description	MAP kinase-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (Mnk1).

CNTN1_HUMAN
θ value	4.42448e-31 (rank : 124)	NC score	0.524012 (rank : 811)
Query Neighborhood Hits	2923	Target Neighborhood Hits	431	Shared Neighborhood Hits	403
SwissProt Accessions	Q12860, Q12861, Q14030, Q8N466	Gene names	CNTN1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3) (Glycoprotein gp135).

CHK2_HUMAN
θ value	5.77852e-31 (rank : 125)	NC score	0.745284 (rank : 44)
Query Neighborhood Hits	2923	Target Neighborhood Hits	859	Shared Neighborhood Hits	790
SwissProt Accessions	O96017, Q6QA03, Q6QA04, Q6QA05, Q6QA06, Q6QA07, Q6QA08, Q6QA10, Q6QA11, Q6QA12, Q6QA13, Q9HCQ8, Q9UGF0, Q9UGF1	Gene names	CHEK2, CHK2
Domain Architecture
Description	Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (Cds1).

DCC_MOUSE
θ value	5.77852e-31 (rank : 126)	NC score	0.548107 (rank : 763)
Query Neighborhood Hits	2923	Target Neighborhood Hits	896	Shared Neighborhood Hits	599
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

KS6A2_MOUSE
θ value	7.54701e-31 (rank : 127)	NC score	0.735010 (rank : 88)
Query Neighborhood Hits	2923	Target Neighborhood Hits	858	Shared Neighborhood Hits	795
SwissProt Accessions	Q9WUT3, Q9D2C0	Gene names	Rps6ka2, Rsk3
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1) (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (Protein-tyrosine kinase Mpk-9) (MAP kinase- activated protein kinase 1c) (MAPKAPK1C).

KS6A3_HUMAN
θ value	1.28732e-30 (rank : 128)	NC score	0.733321 (rank : 104)
Query Neighborhood Hits	2923	Target Neighborhood Hits	859	Shared Neighborhood Hits	795
SwissProt Accessions	P51812, Q4VAP3, Q59H26, Q5JPK8, Q7Z3Z7	Gene names	RPS6KA3, ISPK1, RSK2
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1) (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B).

KS6A3_MOUSE
θ value	1.28732e-30 (rank : 129)	NC score	0.733265 (rank : 105)
Query Neighborhood Hits	2923	Target Neighborhood Hits	860	Shared Neighborhood Hits	795
SwissProt Accessions	P18654, Q03140, Q8K3J8	Gene names	Rps6ka3, Rps6ka-rs1, Rsk2
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1) (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B).

CAMKV_HUMAN
θ value	1.6813e-30 (rank : 130)	NC score	0.741691 (rank : 59)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1084	Shared Neighborhood Hits	867
SwissProt Accessions	Q8NCB2, Q6FIB8, Q8NBS8, Q8NC85, Q8NDU4, Q8WTT8, Q9BQC9, Q9H0Q5	Gene names	CAMKV
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

CAMKV_MOUSE
θ value	1.6813e-30 (rank : 131)	NC score	0.743584 (rank : 48)
Query Neighborhood Hits	2923	Target Neighborhood Hits	848	Shared Neighborhood Hits	787
SwissProt Accessions	Q3UHL1, Q8VD20	Gene names	Camkv
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

MYOTI_MOUSE
θ value	2.86786e-30 (rank : 132)	NC score	0.512757 (rank : 831)
Query Neighborhood Hits	2923	Target Neighborhood Hits	297	Shared Neighborhood Hits	278
SwissProt Accessions	Q9JIF9	Gene names	Myot, Ttid
Domain Architecture	No domain graphic available
Description	Myotilin (Titin immunoglobulin domain protein) (Myofibrillar titin- like Ig domains protein).

PRAX_MOUSE
θ value	2.86786e-30 (rank : 133)	NC score	0.128351 (rank : 1161)
Query Neighborhood Hits	2923	Target Neighborhood Hits	199	Shared Neighborhood Hits	97
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

PTPRS_HUMAN
θ value	2.86786e-30 (rank : 134)	NC score	0.413689 (rank : 933)
Query Neighborhood Hits	2923	Target Neighborhood Hits	472	Shared Neighborhood Hits	398
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

CNTN1_MOUSE
θ value	6.38894e-30 (rank : 135)	NC score	0.524079 (rank : 810)
Query Neighborhood Hits	2923	Target Neighborhood Hits	422	Shared Neighborhood Hits	403
SwissProt Accessions	P12960, Q6NXV7, Q8BR42, Q8C6A0	Gene names	Cntn1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3).

KPCD3_MOUSE
θ value	1.08979e-29 (rank : 136)	NC score	0.735971 (rank : 85)
Query Neighborhood Hits	2923	Target Neighborhood Hits	901	Shared Neighborhood Hits	792
SwissProt Accessions	Q8K1Y2	Gene names	Prkd3, Prkcn
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (nPKC-nu).

KS6A5_HUMAN
θ value	1.08979e-29 (rank : 137)	NC score	0.730445 (rank : 127)
Query Neighborhood Hits	2923	Target Neighborhood Hits	855	Shared Neighborhood Hits	791
SwissProt Accessions	O75582, O95316, Q96AF7	Gene names	RPS6KA5, MSK1
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear mitogen- and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RSKL).

CDON_MOUSE
θ value	1.4233e-29 (rank : 138)	NC score	0.533002 (rank : 801)
Query Neighborhood Hits	2923	Target Neighborhood Hits	410	Shared Neighborhood Hits	374
SwissProt Accessions	Q32MD9, O88971	Gene names	Cdon, Cdo
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

KPCD3_HUMAN
θ value	1.4233e-29 (rank : 139)	NC score	0.735481 (rank : 87)
Query Neighborhood Hits	2923	Target Neighborhood Hits	895	Shared Neighborhood Hits	790
SwissProt Accessions	O94806	Gene names	PRKD3, EPK2, PRKCN
Domain Architecture
Description	Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (nPKC-nu) (Protein kinase EPK2).

MYOTI_HUMAN
θ value	1.85889e-29 (rank : 140)	NC score	0.513420 (rank : 830)
Query Neighborhood Hits	2923	Target Neighborhood Hits	292	Shared Neighborhood Hits	277
SwissProt Accessions	Q9UBF9	Gene names	MYOT, TTID
Domain Architecture	No domain graphic available
Description	Myotilin (Titin immunoglobulin domain protein) (Myofibrillar titin- like Ig domains protein) (57 kDa cytoskeletal protein).

BOC_MOUSE
θ value	3.17079e-29 (rank : 141)	NC score	0.538431 (rank : 786)
Query Neighborhood Hits	2923	Target Neighborhood Hits	433	Shared Neighborhood Hits	386
SwissProt Accessions	Q6AZB0, Q6KAM5, Q6P5H3, Q7TMJ3, Q8CE73, Q8CE91, Q8R377, Q923W7	Gene names	Boc
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

KPCD1_HUMAN
θ value	4.14116e-29 (rank : 142)	NC score	0.736215 (rank : 82)
Query Neighborhood Hits	2923	Target Neighborhood Hits	901	Shared Neighborhood Hits	792
SwissProt Accessions	Q15139	Gene names	PRKD1, PKD, PKD1, PRKCM
Domain Architecture
Description	Serine/threonine-protein kinase D1 (EC 2.7.11.13) (nPKC-D1) (Protein kinase D) (Protein kinase C mu type) (nPKC-mu).

KPCD1_MOUSE
θ value	4.14116e-29 (rank : 143)	NC score	0.735972 (rank : 84)
Query Neighborhood Hits	2923	Target Neighborhood Hits	891	Shared Neighborhood Hits	793
SwissProt Accessions	Q62101	Gene names	Prkd1, Pkcm, Pkd, Prkcm
Domain Architecture
Description	Serine/threonine-protein kinase D1 (EC 2.7.11.13) (nPKC-D1) (Protein kinase D) (Protein kinase C mu type) (nPKC-mu).

KPCD2_HUMAN
θ value	1.2049e-28 (rank : 144)	NC score	0.736888 (rank : 77)
Query Neighborhood Hits	2923	Target Neighborhood Hits	910	Shared Neighborhood Hits	794
SwissProt Accessions	Q9BZL6, Q8TB08, Q9P0T6, Q9Y3X8	Gene names	PRKD2, PKD2
Domain Architecture
Description	Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2).

MAPK2_MOUSE
θ value	1.57365e-28 (rank : 145)	NC score	0.750177 (rank : 34)
Query Neighborhood Hits	2923	Target Neighborhood Hits	831	Shared Neighborhood Hits	783
SwissProt Accessions	P49138, Q6P561	Gene names	Mapkapk2, Rps6kc1
Domain Architecture	No domain graphic available
Description	MAP kinase-activated protein kinase 2 (EC 2.7.11.1) (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAPK-2) (MK2).

KS6A6_HUMAN
θ value	3.50572e-28 (rank : 146)	NC score	0.734051 (rank : 98)
Query Neighborhood Hits	2923	Target Neighborhood Hits	853	Shared Neighborhood Hits	787
SwissProt Accessions	Q9UK32, Q8WX28, Q9H4S6	Gene names	RPS6KA6, RSK4
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-6 (EC 2.7.11.1) (S6K-alpha 6) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4).

LRIG1_HUMAN
θ value	5.97985e-28 (rank : 147)	NC score	0.381708 (rank : 959)
Query Neighborhood Hits	2923	Target Neighborhood Hits	654	Shared Neighborhood Hits	385
SwissProt Accessions	Q96JA1, Q6IQ51, Q96CF9, Q9BYB8, Q9UFI4	Gene names	LRIG1, LIG1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

MAMC1_HUMAN
θ value	5.97985e-28 (rank : 148)	NC score	0.491682 (rank : 854)
Query Neighborhood Hits	2923	Target Neighborhood Hits	357	Shared Neighborhood Hits	328
SwissProt Accessions	Q7Z553	Gene names	MAMDC1, MDGA2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

CHL1_HUMAN
θ value	7.80994e-28 (rank : 149)	NC score	0.518586 (rank : 818)
Query Neighborhood Hits	2923	Target Neighborhood Hits	413	Shared Neighborhood Hits	390
SwissProt Accessions	O00533, Q2M3G2, Q59FY0	Gene names	CHL1, CALL
Domain Architecture	No domain graphic available
Description	Neural cell adhesion molecule L1-like protein precursor (Close homolog of L1).

MAMC1_MOUSE
θ value	7.80994e-28 (rank : 150)	NC score	0.490194 (rank : 856)
Query Neighborhood Hits	2923	Target Neighborhood Hits	357	Shared Neighborhood Hits	327
SwissProt Accessions	P60755	Gene names	Mamdc1, Mdga2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

STK6_MOUSE
θ value	7.80994e-28 (rank : 151)	NC score	0.737515 (rank : 72)
Query Neighborhood Hits	2923	Target Neighborhood Hits	886	Shared Neighborhood Hits	797
SwissProt Accessions	P97477, O35624, Q91YU4	Gene names	Stk6, Ark1, Aurka, Ayk1, Iak1
Domain Architecture
Description	Serine/threonine-protein kinase 6 (EC 2.7.11.1) (Aurora-family kinase 1) (Aurora/IPL1-related kinase 1) (Ipl1- and aurora-related kinase 1) (Aurora-A) (Serine/threonine-protein kinase Ayk1).

LRIG1_MOUSE
θ value	1.02001e-27 (rank : 152)	NC score	0.370598 (rank : 967)
Query Neighborhood Hits	2923	Target Neighborhood Hits	627	Shared Neighborhood Hits	371
SwissProt Accessions	P70193	Gene names	Lrig1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

MAPK3_HUMAN
θ value	1.02001e-27 (rank : 153)	NC score	0.747314 (rank : 42)
Query Neighborhood Hits	2923	Target Neighborhood Hits	807	Shared Neighborhood Hits	762
SwissProt Accessions	Q16644	Gene names	MAPKAPK3
Domain Architecture	No domain graphic available
Description	MAP kinase-activated protein kinase 3 (EC 2.7.11.1) (MAPK-activated protein kinase 3) (MAPKAP kinase 3) (MAPKAPK-3) (Chromosome 3p kinase) (3pK).

BOC_HUMAN
θ value	1.33217e-27 (rank : 154)	NC score	0.539298 (rank : 780)
Query Neighborhood Hits	2923	Target Neighborhood Hits	543	Shared Neighborhood Hits	418
SwissProt Accessions	Q9BWV1, Q6UXJ5, Q8N2P7, Q8NF26	Gene names	BOC
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

SNRK_HUMAN
θ value	2.27234e-27 (rank : 155)	NC score	0.741738 (rank : 58)
Query Neighborhood Hits	2923	Target Neighborhood Hits	855	Shared Neighborhood Hits	790
SwissProt Accessions	Q9NRH2, Q14706, Q68D15, Q6IQ46, Q9NXI7	Gene names	SNRK, KIAA0096, SNFRK
Domain Architecture	No domain graphic available
Description	SNF-related serine/threonine-protein kinase (EC 2.7.11.1) (SNF1- related kinase).

ULK3_MOUSE
θ value	2.27234e-27 (rank : 156)	NC score	0.741036 (rank : 60)
Query Neighborhood Hits	2923	Target Neighborhood Hits	872	Shared Neighborhood Hits	796
SwissProt Accessions	Q3U3Q1, Q8K1X6, Q9DBR8	Gene names	Ulk3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3).

USH2A_HUMAN
θ value	2.27234e-27 (rank : 157)	NC score	0.232701 (rank : 1043)
Query Neighborhood Hits	2923	Target Neighborhood Hits	600	Shared Neighborhood Hits	236
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

MAPK2_HUMAN
θ value	2.96777e-27 (rank : 158)	NC score	0.750018 (rank : 35)
Query Neighborhood Hits	2923	Target Neighborhood Hits	844	Shared Neighborhood Hits	786
SwissProt Accessions	P49137, Q8IYD6	Gene names	MAPKAPK2
Domain Architecture
Description	MAP kinase-activated protein kinase 2 (EC 2.7.11.1) (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAPK-2) (MK2).

CDON_HUMAN
θ value	5.06226e-27 (rank : 159)	NC score	0.532382 (rank : 802)
Query Neighborhood Hits	2923	Target Neighborhood Hits	412	Shared Neighborhood Hits	367
SwissProt Accessions	Q4KMG0, O14631	Gene names	CDON, CDO
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

SNRK_MOUSE
θ value	1.12775e-26 (rank : 160)	NC score	0.740683 (rank : 61)
Query Neighborhood Hits	2923	Target Neighborhood Hits	849	Shared Neighborhood Hits	786
SwissProt Accessions	Q8VDU5, Q91WX6	Gene names	Snrk
Domain Architecture	No domain graphic available
Description	SNF-related serine/threonine-protein kinase (EC 2.7.11.1) (SNF1- related kinase).

MAPK3_MOUSE
θ value	1.92365e-26 (rank : 161)	NC score	0.747900 (rank : 40)
Query Neighborhood Hits	2923	Target Neighborhood Hits	811	Shared Neighborhood Hits	770
SwissProt Accessions	Q3UMW7, Q3T9E6, Q8K0G3	Gene names	Mapkapk3
Domain Architecture	No domain graphic available
Description	MAP kinase-activated protein kinase 3 (EC 2.7.11.1) (MAPK-activated protein kinase 3) (MAPKAP kinase 3) (MAPKAPK-3).

STK33_HUMAN
θ value	1.92365e-26 (rank : 162)	NC score	0.744872 (rank : 45)
Query Neighborhood Hits	2923	Target Neighborhood Hits	879	Shared Neighborhood Hits	807
SwissProt Accessions	Q9BYT3, Q658S6, Q8NEF5	Gene names	STK33
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 33 (EC 2.7.11.1).

LRIG2_HUMAN
θ value	2.51237e-26 (rank : 163)	NC score	0.372883 (rank : 964)
Query Neighborhood Hits	2923	Target Neighborhood Hits	595	Shared Neighborhood Hits	358
SwissProt Accessions	O94898, Q9NSN2	Gene names	LRIG2, KIAA0806, LIG2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor (LIG-2).

NPHN_MOUSE
θ value	5.59698e-26 (rank : 164)	NC score	0.489597 (rank : 859)
Query Neighborhood Hits	2923	Target Neighborhood Hits	370	Shared Neighborhood Hits	345
SwissProt Accessions	Q9QZS7	Gene names	Nphs1, Nphn
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

MDGA1_HUMAN
θ value	7.30988e-26 (rank : 165)	NC score	0.484758 (rank : 863)
Query Neighborhood Hits	2923	Target Neighborhood Hits	358	Shared Neighborhood Hits	332
SwissProt Accessions	Q8NFP4, Q8NBE3	Gene names	MDGA1, MAMDC3
Domain Architecture
Description	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 precursor (MAM domain-containing protein 3) (GPI and MAM protein) (Glycosylphosphatidylinositol-MAM) (GPIM).

LRIG2_MOUSE
θ value	1.24688e-25 (rank : 166)	NC score	0.370585 (rank : 968)
Query Neighborhood Hits	2923	Target Neighborhood Hits	586	Shared Neighborhood Hits	350
SwissProt Accessions	Q52KR2, Q69ZY8	Gene names	Lrig2, Kiaa0806
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor.

PLK4_HUMAN
θ value	1.24688e-25 (rank : 167)	NC score	0.739111 (rank : 62)
Query Neighborhood Hits	2923	Target Neighborhood Hits	884	Shared Neighborhood Hits	796
SwissProt Accessions	O00444, Q8IYF0, Q96Q95	Gene names	PLK4, SAK, STK18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine- protein kinase 18).

PUNC_HUMAN
θ value	1.24688e-25 (rank : 168)	NC score	0.541104 (rank : 774)
Query Neighborhood Hits	2923	Target Neighborhood Hits	449	Shared Neighborhood Hits	393
SwissProt Accessions	Q8IVU1, O95215	Gene names	PUNC
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

STK36_HUMAN
θ value	1.62847e-25 (rank : 169)	NC score	0.731938 (rank : 119)
Query Neighborhood Hits	2923	Target Neighborhood Hits	896	Shared Neighborhood Hits	801
SwissProt Accessions	Q9NRP7, Q8TC32, Q9H9N9, Q9UF35, Q9ULE2	Gene names	STK36, KIAA1278
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog).

STK6_HUMAN
θ value	1.62847e-25 (rank : 170)	NC score	0.737077 (rank : 75)
Query Neighborhood Hits	2923	Target Neighborhood Hits	916	Shared Neighborhood Hits	818
SwissProt Accessions	O14965, O60445, O75873, Q9BQD6, Q9UPG5	Gene names	STK6, AIK, ARK1, AURA, BTAK, STK15
Domain Architecture
Description	Serine/threonine-protein kinase 6 (EC 2.7.11.1) (Serine/threonine kinase 15) (Aurora/IPL1-related kinase 1) (Aurora-related kinase 1) (hARK1) (Aurora-A) (Breast-tumor-amplified kinase).

FCRL5_HUMAN
θ value	2.12685e-25 (rank : 171)	NC score	0.406437 (rank : 942)
Query Neighborhood Hits	2923	Target Neighborhood Hits	267	Shared Neighborhood Hits	250
SwissProt Accessions	Q96RD9, Q495Q2, Q495Q4, Q5VYK9, Q6UY46	Gene names	FCRL5, FCRH5, IRTA2
Domain Architecture	No domain graphic available
Description	Fc receptor-like protein 5 precursor (Immunoglobulin receptor translocation-associated gene 2 protein) (BXMAS1) (CD307 antigen).

LRIG3_MOUSE
θ value	2.12685e-25 (rank : 172)	NC score	0.360288 (rank : 970)
Query Neighborhood Hits	2923	Target Neighborhood Hits	611	Shared Neighborhood Hits	361
SwissProt Accessions	Q6P1C6, Q6ZPE6, Q8BRF0, Q8BS51, Q8C5E4	Gene names	Lrig3, Kiaa3016
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor.

CD22_HUMAN
θ value	4.73814e-25 (rank : 173)	NC score	0.463989 (rank : 886)
Query Neighborhood Hits	2923	Target Neighborhood Hits	365	Shared Neighborhood Hits	323
SwissProt Accessions	P20273, O95699, O95701, O95702, O95703, Q01665, Q92872, Q92873, Q9UQA6, Q9UQA7, Q9UQA8, Q9UQA9, Q9UQB0, Q9Y2A6	Gene names	CD22
Domain Architecture
Description	B-cell receptor CD22 precursor (Leu-14) (B-lymphocyte cell adhesion molecule) (BL-CAM) (Siglec-2).

LRIG3_HUMAN
θ value	4.73814e-25 (rank : 174)	NC score	0.355743 (rank : 973)
Query Neighborhood Hits	2923	Target Neighborhood Hits	601	Shared Neighborhood Hits	357
SwissProt Accessions	Q6UXM1, Q6UXL7, Q8NC72	Gene names	LRIG3, LIG3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor (LIG-3).

MAPK5_MOUSE
θ value	4.73814e-25 (rank : 175)	NC score	0.734441 (rank : 92)
Query Neighborhood Hits	2923	Target Neighborhood Hits	799	Shared Neighborhood Hits	756
SwissProt Accessions	O54992, Q6QME4, Q6QME5, Q6QME6, Q6QME7	Gene names	Mapkapk5
Domain Architecture	No domain graphic available
Description	MAP kinase-activated protein kinase 5 (EC 2.7.11.1) (MAPK-activated protein kinase 5) (MAPKAP kinase 5).

NUAK2_HUMAN
θ value	4.73814e-25 (rank : 176)	NC score	0.738565 (rank : 68)
Query Neighborhood Hits	2923	Target Neighborhood Hits	874	Shared Neighborhood Hits	796
SwissProt Accessions	Q9H093	Gene names	NUAK2
Domain Architecture	No domain graphic available
Description	NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (SNF1/AMP kinase-related kinase) (SNARK).

PUNC_MOUSE
θ value	4.73814e-25 (rank : 177)	NC score	0.538915 (rank : 785)
Query Neighborhood Hits	2923	Target Neighborhood Hits	501	Shared Neighborhood Hits	403
SwissProt Accessions	Q8BQC3, O70246, Q792T2, Q9Z2S6	Gene names	Punc
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

MAPK5_HUMAN
θ value	6.18819e-25 (rank : 178)	NC score	0.733371 (rank : 103)
Query Neighborhood Hits	2923	Target Neighborhood Hits	795	Shared Neighborhood Hits	752
SwissProt Accessions	Q8IW41, O60491, Q86X46, Q9BVX9, Q9UG86	Gene names	MAPKAPK5, PRAK
Domain Architecture	No domain graphic available
Description	MAP kinase-activated protein kinase 5 (EC 2.7.11.1) (MAPK-activated protein kinase 5) (MAPKAP kinase 5) (p38-regulated/activated protein kinase).

PLK4_MOUSE
θ value	6.18819e-25 (rank : 179)	NC score	0.738884 (rank : 64)
Query Neighborhood Hits	2923	Target Neighborhood Hits	879	Shared Neighborhood Hits	796
SwissProt Accessions	Q64702, Q6PEP6, Q78EG6, Q8R0I5, Q9CVR6, Q9CVU6	Gene names	Plk4, Sak, Stk18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine- protein kinase 18).

CEAM5_HUMAN
θ value	8.08199e-25 (rank : 180)	NC score	0.426436 (rank : 914)
Query Neighborhood Hits	2923	Target Neighborhood Hits	343	Shared Neighborhood Hits	320
SwissProt Accessions	P06731	Gene names	CEACAM5, CEA
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 5 precursor (Carcinoembryonic antigen) (CEA) (Meconium antigen 100) (CD66e antigen).

MELK_MOUSE
θ value	8.08199e-25 (rank : 181)	NC score	0.738819 (rank : 66)
Query Neighborhood Hits	2923	Target Neighborhood Hits	860	Shared Neighborhood Hits	794
SwissProt Accessions	Q61846, Q61804, Q6ZQH6	Gene names	Melk, Kiaa0175, Pk38
Domain Architecture	No domain graphic available
Description	Maternal embryonic leucine zipper kinase (EC 2.7.11.1) (Protein kinase PK38) (mPK38).

BRSK1_HUMAN
θ value	1.80048e-24 (rank : 182)	NC score	0.738745 (rank : 67)
Query Neighborhood Hits	2923	Target Neighborhood Hits	942	Shared Neighborhood Hits	814
SwissProt Accessions	Q8TDC3, Q5J5B5, Q8NDD0, Q8NDR4, Q8TDC2, Q96AV4, Q96JL4	Gene names	BRSK1, KIAA1811, SAD1
Domain Architecture
Description	BR serine/threonine-protein kinase 1 (EC 2.7.11.1) (SAD1 kinase) (SAD1A).

MKNK1_HUMAN
θ value	1.80048e-24 (rank : 183)	NC score	0.708227 (rank : 276)
Query Neighborhood Hits	2923	Target Neighborhood Hits	701	Shared Neighborhood Hits	655
SwissProt Accessions	Q9BUB5, O00312, Q5TC06, Q6V0N6	Gene names	MKNK1, MNK1
Domain Architecture
Description	MAP kinase-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (Mnk1).

NIM1_HUMAN
θ value	1.80048e-24 (rank : 184)	NC score	0.736517 (rank : 80)
Query Neighborhood Hits	2923	Target Neighborhood Hits	850	Shared Neighborhood Hits	791
SwissProt Accessions	Q8IY84	Gene names	NIM1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase NIM1 (EC 2.7.11.1).

NIM1_MOUSE
θ value	1.80048e-24 (rank : 185)	NC score	0.737295 (rank : 74)
Query Neighborhood Hits	2923	Target Neighborhood Hits	850	Shared Neighborhood Hits	792
SwissProt Accessions	Q8BHI9, Q8BXQ9	Gene names	NIM1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase NIM1 (EC 2.7.11.1).

VGFR1_HUMAN
θ value	2.35151e-24 (rank : 186)	NC score	0.692595 (rank : 372)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1109	Shared Neighborhood Hits	1033
SwissProt Accessions	P17948, O60722, P16057, Q12954	Gene names	FLT1, FLT, FRT
Domain Architecture
Description	Vascular endothelial growth factor receptor 1 precursor (EC 2.7.10.1) (VEGFR-1) (Vascular permeability factor receptor) (Tyrosine-protein kinase receptor FLT) (Flt-1) (Tyrosine-protein kinase FRT) (Fms-like tyrosine kinase 1).

PKN2_HUMAN
θ value	3.07116e-24 (rank : 187)	NC score	0.715528 (rank : 218)
Query Neighborhood Hits	2923	Target Neighborhood Hits	892	Shared Neighborhood Hits	814
SwissProt Accessions	Q16513, Q9H1W4	Gene names	PKN2, PRK2, PRKCL2
Domain Architecture
Description	Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein kinase C- like 2) (Protein-kinase C-related kinase 2).

ULK2_MOUSE
θ value	3.07116e-24 (rank : 188)	NC score	0.732899 (rank : 107)
Query Neighborhood Hits	2923	Target Neighborhood Hits	943	Shared Neighborhood Hits	823
SwissProt Accessions	Q9QY01, Q80TV7, Q9WTP4	Gene names	Ulk2, Kiaa0623
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2) (Serine/threonine-protein kinase Unc51.2).

MELK_HUMAN
θ value	4.01107e-24 (rank : 189)	NC score	0.738439 (rank : 69)
Query Neighborhood Hits	2923	Target Neighborhood Hits	847	Shared Neighborhood Hits	786
SwissProt Accessions	Q14680, Q7L3C3	Gene names	MELK, KIAA0175
Domain Architecture	No domain graphic available
Description	Maternal embryonic leucine zipper kinase (EC 2.7.11.1) (hMELK) (Protein kinase PK38) (hPK38).

PKN2_MOUSE
θ value	4.01107e-24 (rank : 190)	NC score	0.715806 (rank : 215)
Query Neighborhood Hits	2923	Target Neighborhood Hits	899	Shared Neighborhood Hits	818
SwissProt Accessions	Q8BWW9, Q80WS2, Q8BJL7	Gene names	Pkn2, Prkcl2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein kinase C- like 2) (Protein-kinase C-related kinase 2).

ULK2_HUMAN
θ value	4.01107e-24 (rank : 191)	NC score	0.732458 (rank : 115)
Query Neighborhood Hits	2923	Target Neighborhood Hits	979	Shared Neighborhood Hits	826
SwissProt Accessions	Q8IYT8, O75119	Gene names	ULK2, KIAA0623
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2).

NPHN_HUMAN
θ value	5.23862e-24 (rank : 192)	NC score	0.492496 (rank : 852)
Query Neighborhood Hits	2923	Target Neighborhood Hits	362	Shared Neighborhood Hits	337
SwissProt Accessions	O60500	Gene names	NPHS1, NPHN
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

K0999_MOUSE
θ value	6.84181e-24 (rank : 193)	NC score	0.732888 (rank : 108)
Query Neighborhood Hits	2923	Target Neighborhood Hits	931	Shared Neighborhood Hits	811
SwissProt Accessions	Q6P4S6, Q641L5, Q66JZ5, Q6ZQ09, Q8K075, Q9CYD5	Gene names	Kiaa0999
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase KIAA0999 (EC 2.7.11.1).

PAK6_HUMAN
θ value	6.84181e-24 (rank : 194)	NC score	0.722729 (rank : 166)
Query Neighborhood Hits	2923	Target Neighborhood Hits	915	Shared Neighborhood Hits	832
SwissProt Accessions	Q9NQU5	Gene names	PAK6, PAK5
Domain Architecture
Description	Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1) (p21-activated kinase 6) (PAK-6) (PAK-5).

K0999_HUMAN
θ value	8.93572e-24 (rank : 195)	NC score	0.732853 (rank : 109)
Query Neighborhood Hits	2923	Target Neighborhood Hits	899	Shared Neighborhood Hits	801
SwissProt Accessions	Q9Y2K2, Q59FY2, Q5M9N1, Q6P3R6, Q8IYM8, Q9HA50	Gene names	KIAA0999
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase KIAA0999 (EC 2.7.11.1).

NUAK2_MOUSE
θ value	1.16704e-23 (rank : 196)	NC score	0.737880 (rank : 70)
Query Neighborhood Hits	2923	Target Neighborhood Hits	878	Shared Neighborhood Hits	796
SwissProt Accessions	Q8BZN4, Q80ZW3, Q8CIC0, Q9DBV0	Gene names	Nuak2
Domain Architecture	No domain graphic available
Description	NUAK family SNF1-like kinase 2 (EC 2.7.11.1).

SN1L1_MOUSE
θ value	1.16704e-23 (rank : 197)	NC score	0.734056 (rank : 97)
Query Neighborhood Hits	2923	Target Neighborhood Hits	895	Shared Neighborhood Hits	808
SwissProt Accessions	Q60670	Gene names	Snf1lk, Msk
Domain Architecture
Description	Serine/threonine-protein kinase SNF1-like kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) (HRT-20) (Myocardial SNF1- like kinase).

AKT1_HUMAN
θ value	1.5242e-23 (rank : 198)	NC score	0.719466 (rank : 186)
Query Neighborhood Hits	2923	Target Neighborhood Hits	885	Shared Neighborhood Hits	789
SwissProt Accessions	P31749, Q9BWB6	Gene names	AKT1, PKB, RAC
Domain Architecture
Description	RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-alpha) (Protein kinase B) (PKB) (C-AKT).

CD22_MOUSE
θ value	1.99067e-23 (rank : 199)	NC score	0.459307 (rank : 895)
Query Neighborhood Hits	2923	Target Neighborhood Hits	331	Shared Neighborhood Hits	296
SwissProt Accessions	P35329, Q9JHL2, Q9JJX9, Q9JJY0, Q9JJY1, Q9R056, Q9R094, Q9WU51	Gene names	Cd22, Lyb-8
Domain Architecture
Description	B-cell receptor CD22 precursor (Leu-14) (B-lymphocyte cell adhesion molecule) (BL-CAM) (Siglec-2).

NUAK1_MOUSE
θ value	1.99067e-23 (rank : 200)	NC score	0.736785 (rank : 78)
Query Neighborhood Hits	2923	Target Neighborhood Hits	881	Shared Neighborhood Hits	800
SwissProt Accessions	Q641K5, Q6I6D6, Q8CGE1	Gene names	Nuak1, Kiaa0537
Domain Architecture	No domain graphic available
Description	NUAK family SNF1-like kinase 1 (EC 2.7.11.1).

NUAK1_HUMAN
θ value	2.59989e-23 (rank : 201)	NC score	0.736528 (rank : 79)
Query Neighborhood Hits	2923	Target Neighborhood Hits	874	Shared Neighborhood Hits	795
SwissProt Accessions	O60285, Q96KA8	Gene names	NUAK1, ARK5, KIAA0537
Domain Architecture	No domain graphic available
Description	NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase 5).

TENN_MOUSE
θ value	2.59989e-23 (rank : 202)	NC score	0.200909 (rank : 1081)
Query Neighborhood Hits	2923	Target Neighborhood Hits	484	Shared Neighborhood Hits	190
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

BRSK2_HUMAN
θ value	5.79196e-23 (rank : 203)	NC score	0.737349 (rank : 73)
Query Neighborhood Hits	2923	Target Neighborhood Hits	897	Shared Neighborhood Hits	810
SwissProt Accessions	Q8IWQ3, O60843, O95099, Q5J5B4, Q8TB60	Gene names	BRSK2, C11orf7, PEN11B, STK29
Domain Architecture
Description	BR serine/threonine-protein kinase 2 (EC 2.7.11.1) (Serine/threonine- protein kinase 29) (SAD1B).

KS6A4_MOUSE
θ value	5.79196e-23 (rank : 204)	NC score	0.726584 (rank : 152)
Query Neighborhood Hits	2923	Target Neighborhood Hits	866	Shared Neighborhood Hits	793
SwissProt Accessions	Q9Z2B9, Q91X18	Gene names	Rps6ka4, Msk2
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-4 (EC 2.7.11.1) (Nuclear mitogen- and stress-activated protein kinase 2) (90 kDa ribosomal protein S6 kinase 4) (RSK-like protein kinase) (RLSK).

VCAM1_MOUSE
θ value	5.79196e-23 (rank : 205)	NC score	0.478554 (rank : 874)
Query Neighborhood Hits	2923	Target Neighborhood Hits	320	Shared Neighborhood Hits	300
SwissProt Accessions	P29533	Gene names	Vcam1, Vcam-1
Domain Architecture
Description	Vascular cell adhesion protein 1 precursor (V-CAM 1).

AKT1_MOUSE
θ value	7.56453e-23 (rank : 206)	NC score	0.718919 (rank : 190)
Query Neighborhood Hits	2923	Target Neighborhood Hits	878	Shared Neighborhood Hits	788
SwissProt Accessions	P31750, Q62274	Gene names	Akt1, Akt, Rac
Domain Architecture
Description	RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-alpha) (AKT1 kinase) (Protein kinase B) (PKB) (C-AKT) (Thymoma viral proto- oncogene).

TXND2_HUMAN
θ value	9.87957e-23 (rank : 207)	NC score	0.117276 (rank : 1174)
Query Neighborhood Hits	2923	Target Neighborhood Hits	793	Shared Neighborhood Hits	378
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

AKT2_HUMAN
θ value	1.29031e-22 (rank : 208)	NC score	0.721903 (rank : 172)
Query Neighborhood Hits	2923	Target Neighborhood Hits	878	Shared Neighborhood Hits	785
SwissProt Accessions	P31751, Q68GC0	Gene names	AKT2
Domain Architecture
Description	RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta).

ULK1_MOUSE
θ value	1.29031e-22 (rank : 209)	NC score	0.728987 (rank : 139)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1214	Shared Neighborhood Hits	905
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

KS6A4_HUMAN
θ value	1.6852e-22 (rank : 210)	NC score	0.725967 (rank : 158)
Query Neighborhood Hits	2923	Target Neighborhood Hits	868	Shared Neighborhood Hits	792
SwissProt Accessions	O75676, O75585, Q53ES8	Gene names	RPS6KA4, MSK2
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-4 (EC 2.7.11.1) (Nuclear mitogen- and stress-activated protein kinase 2) (90 kDa ribosomal protein S6 kinase 4) (Ribosomal protein kinase B) (RSKB).

VGFR1_MOUSE
θ value	1.6852e-22 (rank : 211)	NC score	0.694244 (rank : 354)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1118	Shared Neighborhood Hits	1032
SwissProt Accessions	P35969, O55094, Q61517	Gene names	Flt1, Emrk2, Flt
Domain Architecture
Description	Vascular endothelial growth factor receptor 1 precursor (EC 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) (Embryonic receptor kinase 2).

PKN1_HUMAN
θ value	2.20094e-22 (rank : 212)	NC score	0.713483 (rank : 234)
Query Neighborhood Hits	2923	Target Neighborhood Hits	886	Shared Neighborhood Hits	805
SwissProt Accessions	Q16512, Q15143, Q8IUV5	Gene names	PKN1, PKN, PRK1, PRKCL1
Domain Architecture
Description	Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protein kinase C- like 1) (Protein-kinase C-related kinase 1) (Protein kinase C-like PKN) (Serine-threonine protein kinase N) (Protein kinase PKN-alpha).

TENA_HUMAN
θ value	2.20094e-22 (rank : 213)	NC score	0.149852 (rank : 1137)
Query Neighborhood Hits	2923	Target Neighborhood Hits	631	Shared Neighborhood Hits	203
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

AKT3_HUMAN
θ value	2.87452e-22 (rank : 214)	NC score	0.722391 (rank : 168)
Query Neighborhood Hits	2923	Target Neighborhood Hits	872	Shared Neighborhood Hits	789
SwissProt Accessions	Q9Y243, Q96QV3, Q9UFP5	Gene names	AKT3
Domain Architecture
Description	RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) (STK-2).

AKT3_MOUSE
θ value	2.87452e-22 (rank : 215)	NC score	0.722375 (rank : 169)
Query Neighborhood Hits	2923	Target Neighborhood Hits	872	Shared Neighborhood Hits	789
SwissProt Accessions	Q9WUA6	Gene names	Akt3
Domain Architecture
Description	RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma).

AURKC_HUMAN
θ value	2.87452e-22 (rank : 216)	NC score	0.737052 (rank : 76)
Query Neighborhood Hits	2923	Target Neighborhood Hits	847	Shared Neighborhood Hits	789
SwissProt Accessions	Q9UQB9, O60681, O75442, Q9UPK5	Gene names	AURKC, AIE2, AIK3, STK13
Domain Architecture
Description	Serine/threonine-protein kinase 13 (EC 2.7.11.1) (Aurora/Ipl1/Eg2 protein 2) (Aurora/Ipl1-related kinase 3) (Aurora-C).

KIRR1_MOUSE
θ value	2.87452e-22 (rank : 217)	NC score	0.429438 (rank : 909)
Query Neighborhood Hits	2923	Target Neighborhood Hits	403	Shared Neighborhood Hits	333
SwissProt Accessions	Q80W68, Q8CIJ4, Q8CJ59, Q923L4	Gene names	Kirrel1, Kirrel, Neph1
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 1 precursor (Kin of irregular chiasm-like protein 1) (Nephrin-like protein 1).

NEK1_HUMAN
θ value	2.87452e-22 (rank : 218)	NC score	0.721604 (rank : 174)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1129	Shared Neighborhood Hits	929
SwissProt Accessions	Q96PY6, Q9Y594	Gene names	NEK1, KIAA1901
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1) (NY-REN-55 antigen).

ULK1_HUMAN
θ value	3.75424e-22 (rank : 219)	NC score	0.730301 (rank : 128)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1121	Shared Neighborhood Hits	865
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).

AURKC_MOUSE
θ value	4.9032e-22 (rank : 220)	NC score	0.738877 (rank : 65)
Query Neighborhood Hits	2923	Target Neighborhood Hits	844	Shared Neighborhood Hits	788
SwissProt Accessions	O88445, Q9JLC2	Gene names	Aurkc, Aie1, Stk13
Domain Architecture
Description	Serine/threonine-protein kinase 13 (EC 2.7.11.1) (Aurora/Ipl1/Eg2 protein 1) (Aurora-C).

TENR_MOUSE
θ value	4.9032e-22 (rank : 221)	NC score	0.193237 (rank : 1090)
Query Neighborhood Hits	2923	Target Neighborhood Hits	531	Shared Neighborhood Hits	211
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

MUSK_HUMAN
θ value	6.40375e-22 (rank : 222)	NC score	0.705582 (rank : 287)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1074	Shared Neighborhood Hits	1002
SwissProt Accessions	O15146	Gene names	MUSK
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (Muscle-specific kinase receptor) (MuSK).

AKT2_MOUSE
θ value	8.36355e-22 (rank : 223)	NC score	0.721121 (rank : 177)
Query Neighborhood Hits	2923	Target Neighborhood Hits	875	Shared Neighborhood Hits	784
SwissProt Accessions	Q60823	Gene names	Akt2
Domain Architecture
Description	RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta).

KIRR1_HUMAN
θ value	8.36355e-22 (rank : 224)	NC score	0.432821 (rank : 906)
Query Neighborhood Hits	2923	Target Neighborhood Hits	401	Shared Neighborhood Hits	332
SwissProt Accessions	Q96J84, Q5XKC6, Q7Z696, Q7Z7N8, Q8TB15, Q9H9N1, Q9NVA5	Gene names	KIRREL, NEPH1
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 1 precursor (Kin of irregular chiasm-like protein 1) (Nephrin-like protein 1).

PAK2_MOUSE
θ value	8.36355e-22 (rank : 225)	NC score	0.718021 (rank : 200)
Query Neighborhood Hits	2923	Target Neighborhood Hits	858	Shared Neighborhood Hits	797
SwissProt Accessions	Q8CIN4	Gene names	Pak2
Domain Architecture
Description	Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (p21-activated kinase 2) (PAK-2).

PKN1_MOUSE
θ value	8.36355e-22 (rank : 226)	NC score	0.714080 (rank : 227)
Query Neighborhood Hits	2923	Target Neighborhood Hits	888	Shared Neighborhood Hits	801
SwissProt Accessions	P70268, Q7TST2	Gene names	Pkn1, Pkn, Prk1, Prkcl1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protein kinase C- like 1) (Protein-kinase C-related kinase 1) (Protein kinase C-like PKN) (Serine-threonine protein kinase N).

AAPK2_HUMAN
θ value	1.09232e-21 (rank : 227)	NC score	0.734849 (rank : 90)
Query Neighborhood Hits	2923	Target Neighborhood Hits	843	Shared Neighborhood Hits	789
SwissProt Accessions	P54646, Q9H1E8, Q9UD43	Gene names	PRKAA2, AMPK, AMPK2
Domain Architecture
Description	5'-AMP-activated protein kinase catalytic subunit alpha-2 (EC 2.7.11.1) (AMPK alpha-2 chain).

NEK1_MOUSE
θ value	1.09232e-21 (rank : 228)	NC score	0.722421 (rank : 167)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1311	Shared Neighborhood Hits	995
SwissProt Accessions	P51954	Gene names	Nek1
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1).

SN1L1_HUMAN
θ value	1.09232e-21 (rank : 229)	NC score	0.734066 (rank : 96)
Query Neighborhood Hits	2923	Target Neighborhood Hits	911	Shared Neighborhood Hits	810
SwissProt Accessions	P57059, Q5R2V5, Q86YJ2	Gene names	SNF1LK
Domain Architecture
Description	Serine/threonine-protein kinase SNF1-like kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase SNF1LK).

VCAM1_HUMAN
θ value	1.09232e-21 (rank : 230)	NC score	0.479537 (rank : 871)
Query Neighborhood Hits	2923	Target Neighborhood Hits	352	Shared Neighborhood Hits	313
SwissProt Accessions	P19320, Q6NUP8	Gene names	VCAM1, L1CAM
Domain Architecture
Description	Vascular cell adhesion protein 1 precursor (V-CAM 1) (CD106 antigen) (INCAM-100).

PAK2_HUMAN
θ value	1.42661e-21 (rank : 231)	NC score	0.718346 (rank : 198)
Query Neighborhood Hits	2923	Target Neighborhood Hits	862	Shared Neighborhood Hits	802
SwissProt Accessions	Q13177, Q13154	Gene names	PAK2
Domain Architecture
Description	Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (p21-activated kinase 2) (PAK-2) (PAK65) (Gamma-PAK) (S6/H4 kinase).

USH2A_MOUSE
θ value	1.42661e-21 (rank : 232)	NC score	0.223892 (rank : 1056)
Query Neighborhood Hits	2923	Target Neighborhood Hits	626	Shared Neighborhood Hits	241
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

MUSK_MOUSE
θ value	1.86321e-21 (rank : 233)	NC score	0.702705 (rank : 303)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1057	Shared Neighborhood Hits	994
SwissProt Accessions	Q61006, Q61005, Q61987, Q61988	Gene names	Musk, Nsk2
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific kinase receptor) (MuSK).

NACAM_MOUSE
θ value	1.86321e-21 (rank : 234)	NC score	0.125039 (rank : 1162)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1866	Shared Neighborhood Hits	663
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

SGK1_HUMAN
θ value	1.86321e-21 (rank : 235)	NC score	0.720859 (rank : 179)
Query Neighborhood Hits	2923	Target Neighborhood Hits	848	Shared Neighborhood Hits	786
SwissProt Accessions	O00141, Q5TCN3, Q9UN56	Gene names	SGK, SGK1
Domain Architecture
Description	Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 1).

STK36_MOUSE
θ value	1.86321e-21 (rank : 236)	NC score	0.729450 (rank : 135)
Query Neighborhood Hits	2923	Target Neighborhood Hits	877	Shared Neighborhood Hits	799
SwissProt Accessions	Q69ZM6, Q6PDI0, Q80XQ6	Gene names	Stk36, Kiaa1278
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog).

AAPK1_HUMAN
θ value	3.17815e-21 (rank : 237)	NC score	0.734164 (rank : 95)
Query Neighborhood Hits	2923	Target Neighborhood Hits	842	Shared Neighborhood Hits	788
SwissProt Accessions	Q13131, O00286, Q5D0E1, Q9UNQ4	Gene names	PRKAA1, AMPK1
Domain Architecture
Description	5'-AMP-activated protein kinase catalytic subunit alpha-1 (EC 2.7.11.1) (AMPK alpha-1 chain).

KS6A5_MOUSE
θ value	3.17815e-21 (rank : 238)	NC score	0.722061 (rank : 171)
Query Neighborhood Hits	2923	Target Neighborhood Hits	854	Shared Neighborhood Hits	791
SwissProt Accessions	Q8C050, Q8CI92	Gene names	Rps6ka5, Msk1
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear mitogen- and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RLSK).

PASK_MOUSE
θ value	3.17815e-21 (rank : 239)	NC score	0.734987 (rank : 89)
Query Neighborhood Hits	2923	Target Neighborhood Hits	867	Shared Neighborhood Hits	780
SwissProt Accessions	Q8CEE6, Q91YD8	Gene names	Pask, Kiaa0135
Domain Architecture
Description	PAS domain-containing serine/threonine-protein kinase (EC 2.7.11.1) (PAS-kinase) (PASKIN).

PRKX_HUMAN
θ value	3.17815e-21 (rank : 240)	NC score	0.724984 (rank : 159)
Query Neighborhood Hits	2923	Target Neighborhood Hits	847	Shared Neighborhood Hits	786
SwissProt Accessions	P51817	Gene names	PRKX, PKX1
Domain Architecture
Description	Serine/threonine-protein kinase PRKX (EC 2.7.11.1) (Protein kinase PKX1).

AURKB_MOUSE
θ value	4.15078e-21 (rank : 241)	NC score	0.736398 (rank : 81)
Query Neighborhood Hits	2923	Target Neighborhood Hits	858	Shared Neighborhood Hits	790
SwissProt Accessions	O70126, Q61882	Gene names	Aurkb, Ark2, Stk1, Stk12, Stk5
Domain Architecture
Description	Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-B) (Aurora- related kinase 2) (Serine/threonine-protein kinase 5) (STK-1).

PAK3_MOUSE
θ value	4.15078e-21 (rank : 242)	NC score	0.715716 (rank : 216)
Query Neighborhood Hits	2923	Target Neighborhood Hits	874	Shared Neighborhood Hits	795
SwissProt Accessions	Q61036, O88645, Q8K1R5, Q8K1R6	Gene names	Pak3, Pak-3, Pakb, Stk4
Domain Architecture
Description	Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (p21-activated kinase 3) (PAK-3) (Beta-PAK) (CDC42/RAC effector kinase PAK-B).

PKN3_HUMAN
θ value	4.15078e-21 (rank : 243)	NC score	0.716943 (rank : 204)
Query Neighborhood Hits	2923	Target Neighborhood Hits	893	Shared Neighborhood Hits	811
SwissProt Accessions	Q6P5Z2, Q9UM03	Gene names	PKN3, PKNBETA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

SGK2_HUMAN
θ value	5.42112e-21 (rank : 244)	NC score	0.720856 (rank : 180)
Query Neighborhood Hits	2923	Target Neighborhood Hits	840	Shared Neighborhood Hits	788
SwissProt Accessions	Q9HBY8, Q9UKG6	Gene names	SGK2
Domain Architecture
Description	Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 2).

STK11_HUMAN
θ value	5.42112e-21 (rank : 245)	NC score	0.733980 (rank : 99)
Query Neighborhood Hits	2923	Target Neighborhood Hits	831	Shared Neighborhood Hits	779
SwissProt Accessions	Q15831	Gene names	STK11, LKB1, PJS
Domain Architecture
Description	Serine/threonine-protein kinase 11 (EC 2.7.11.1) (Serine/threonine- protein kinase LKB1) (NY-REN-19 antigen).

VGFR2_HUMAN
θ value	5.42112e-21 (rank : 246)	NC score	0.682557 (rank : 446)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1103	Shared Neighborhood Hits	1019
SwissProt Accessions	P35968, O60723, Q14178	Gene names	KDR, FLK1
Domain Architecture
Description	Vascular endothelial growth factor receptor 2 precursor (EC 2.7.10.1) (VEGFR-2) (Kinase insert domain receptor) (Protein-tyrosine kinase receptor Flk-1) (CD309 antigen).

PAK7_MOUSE
θ value	7.0802e-21 (rank : 247)	NC score	0.719071 (rank : 189)
Query Neighborhood Hits	2923	Target Neighborhood Hits	875	Shared Neighborhood Hits	793
SwissProt Accessions	Q8C015, Q3TQJ7, Q6RWS7	Gene names	Pak7, Pak5
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PAK 7 (EC 2.7.11.1) (p21-activated kinase 7) (PAK-7) (p21-activated kinase 5).

MARK3_MOUSE
θ value	9.24701e-21 (rank : 248)	NC score	0.728840 (rank : 140)
Query Neighborhood Hits	2923	Target Neighborhood Hits	919	Shared Neighborhood Hits	816
SwissProt Accessions	Q03141, Q3TM40, Q3V1U3, Q8C6G9, Q8R375, Q9JKE4	Gene names	Mark3, Emk2, Mpk10
Domain Architecture	No domain graphic available
Description	MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (MPK-10) (ELKL motif kinase 2).

PAK7_HUMAN
θ value	9.24701e-21 (rank : 249)	NC score	0.718795 (rank : 193)
Query Neighborhood Hits	2923	Target Neighborhood Hits	875	Shared Neighborhood Hits	792
SwissProt Accessions	Q9P286, Q5W115, Q9BX09, Q9ULF6	Gene names	PAK7, KIAA1264, PAK5
Domain Architecture
Description	Serine/threonine-protein kinase PAK 7 (EC 2.7.11.1) (p21-activated kinase 7) (PAK-7) (PAK-5).

AAPK1_MOUSE
θ value	1.2077e-20 (rank : 250)	NC score	0.733900 (rank : 100)
Query Neighborhood Hits	2923	Target Neighborhood Hits	843	Shared Neighborhood Hits	788
SwissProt Accessions	Q5EG47	Gene names	Prkaa1
Domain Architecture	No domain graphic available
Description	5'-AMP-activated protein kinase catalytic subunit alpha-1 (EC 2.7.11.1) (AMPK alpha-1 chain).

KPCT_MOUSE
θ value	1.5773e-20 (rank : 251)	NC score	0.712053 (rank : 240)
Query Neighborhood Hits	2923	Target Neighborhood Hits	895	Shared Neighborhood Hits	785
SwissProt Accessions	Q02111	Gene names	Prkcq, Pkcq
Domain Architecture
Description	Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta).

PAK1_HUMAN
θ value	1.5773e-20 (rank : 252)	NC score	0.715909 (rank : 213)
Query Neighborhood Hits	2923	Target Neighborhood Hits	873	Shared Neighborhood Hits	802
SwissProt Accessions	Q13153, O75561, Q13567, Q32M53, Q32M54, Q86W79	Gene names	PAK1
Domain Architecture
Description	Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (p21-activated kinase 1) (PAK-1) (P65-PAK) (Alpha-PAK).

SN1L2_HUMAN
θ value	1.5773e-20 (rank : 253)	NC score	0.733489 (rank : 102)
Query Neighborhood Hits	2923	Target Neighborhood Hits	964	Shared Neighborhood Hits	855
SwissProt Accessions	Q9H0K1, O94878, Q6AZE2, Q76N03, Q8NCV7, Q96CZ8	Gene names	SNF1LK2, KIAA0781, QIK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SNF1-like kinase 2 (EC 2.7.11.1) (Qin- induced kinase).

TENN_HUMAN
θ value	1.5773e-20 (rank : 254)	NC score	0.181253 (rank : 1102)
Query Neighborhood Hits	2923	Target Neighborhood Hits	453	Shared Neighborhood Hits	178
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

ULK3_HUMAN
θ value	1.5773e-20 (rank : 255)	NC score	0.738890 (rank : 63)
Query Neighborhood Hits	2923	Target Neighborhood Hits	830	Shared Neighborhood Hits	783
SwissProt Accessions	Q6PHR2, Q9NPN5, Q9UFS4	Gene names	ULK3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3).

MARK2_HUMAN
θ value	2.06002e-20 (rank : 256)	NC score	0.729811 (rank : 131)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1056	Shared Neighborhood Hits	861
SwissProt Accessions	Q7KZI7, Q15449, Q15524, Q5XGA3, Q68A18, Q96HB3, Q96RG0	Gene names	MARK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog).

NEK3_MOUSE
θ value	2.06002e-20 (rank : 257)	NC score	0.723506 (rank : 164)
Query Neighborhood Hits	2923	Target Neighborhood Hits	854	Shared Neighborhood Hits	793
SwissProt Accessions	Q9R0A5, Q9Z0X9	Gene names	Nek3
Domain Architecture
Description	Serine/threonine-protein kinase Nek3 (EC 2.7.11.1) (NimA-related protein kinase 3).

PASK_HUMAN
θ value	2.06002e-20 (rank : 258)	NC score	0.732734 (rank : 112)
Query Neighborhood Hits	2923	Target Neighborhood Hits	857	Shared Neighborhood Hits	776
SwissProt Accessions	Q96RG2, Q86XH6, Q99763, Q9UFR7	Gene names	PASK, KIAA0135
Domain Architecture
Description	PAS domain-containing serine/threonine-protein kinase (EC 2.7.11.1) (PAS-kinase) (PASKIN) (hPASK).

SGK1_MOUSE
θ value	2.06002e-20 (rank : 259)	NC score	0.720682 (rank : 182)
Query Neighborhood Hits	2923	Target Neighborhood Hits	848	Shared Neighborhood Hits	786
SwissProt Accessions	Q9WVC6	Gene names	Sgk, Sgk1
Domain Architecture
Description	Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 1).

SN1L2_MOUSE
θ value	2.69047e-20 (rank : 260)	NC score	0.732439 (rank : 116)
Query Neighborhood Hits	2923	Target Neighborhood Hits	944	Shared Neighborhood Hits	841
SwissProt Accessions	Q8CFH6	Gene names	Snf1lk2, Sik2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SNF1-like kinase 2 (EC 2.7.11.1) (Salt-inducible kinase 2).

NTRI_HUMAN
θ value	3.51386e-20 (rank : 261)	NC score	0.487882 (rank : 861)
Query Neighborhood Hits	2923	Target Neighborhood Hits	344	Shared Neighborhood Hits	335
SwissProt Accessions	Q9P121, Q6UXJ3, Q86VJ9	Gene names	NT
Domain Architecture
Description	Neurotrimin precursor (hNT).

PAK3_HUMAN
θ value	3.51386e-20 (rank : 262)	NC score	0.715595 (rank : 217)
Query Neighborhood Hits	2923	Target Neighborhood Hits	887	Shared Neighborhood Hits	810
SwissProt Accessions	O75914, Q5JWX1, Q5JWX2, Q7Z2D6, Q7Z2E4, Q7Z3Z8, Q8WWK5, Q8WX23, Q9P0J8	Gene names	PAK3, OPHN3
Domain Architecture
Description	Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (p21-activated kinase 3) (PAK-3) (Beta-PAK) (Oligophrenin-3).

PRKX_MOUSE
θ value	3.51386e-20 (rank : 263)	NC score	0.726439 (rank : 154)
Query Neighborhood Hits	2923	Target Neighborhood Hits	846	Shared Neighborhood Hits	789
SwissProt Accessions	Q922R0, Q3UCD1, Q8BHD6, Q9QZ12	Gene names	Prkx, Pkare
Domain Architecture
Description	Serine/threonine-protein kinase PRKX (EC 2.7.11.1) (PKA-related protein kinase).

SGK2_MOUSE
θ value	3.51386e-20 (rank : 264)	NC score	0.720891 (rank : 178)
Query Neighborhood Hits	2923	Target Neighborhood Hits	833	Shared Neighborhood Hits	784
SwissProt Accessions	Q9QZS5, Q8R0P6	Gene names	Sgk2
Domain Architecture
Description	Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 2).

SGK3_HUMAN
θ value	3.51386e-20 (rank : 265)	NC score	0.716430 (rank : 207)
Query Neighborhood Hits	2923	Target Neighborhood Hits	877	Shared Neighborhood Hits	783
SwissProt Accessions	Q96BR1, Q9P1Q7, Q9UKG5	Gene names	SGK3, SGKL
Domain Architecture
Description	Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid- regulated kinase-like).

CDKL2_MOUSE
θ value	4.58923e-20 (rank : 266)	NC score	0.708519 (rank : 273)
Query Neighborhood Hits	2923	Target Neighborhood Hits	854	Shared Neighborhood Hits	785
SwissProt Accessions	Q9QUK0, Q3UL60, Q3V3X7, Q9QYI1, Q9QYI2	Gene names	Cdkl2, Kkiamre, Kkm
Domain Architecture	No domain graphic available
Description	Cyclin-dependent kinase-like 2 (EC 2.7.11.22) (Serine/threonine- protein kinase KKIAMRE).

MARK1_HUMAN
θ value	4.58923e-20 (rank : 267)	NC score	0.728160 (rank : 143)
Query Neighborhood Hits	2923	Target Neighborhood Hits	887	Shared Neighborhood Hits	804
SwissProt Accessions	Q9P0L2, Q5VTF9, Q5VTG0, Q96SW9, Q9P251	Gene names	MARK1, KIAA1477, MARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MARK1 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 1).

MARK1_MOUSE
θ value	4.58923e-20 (rank : 268)	NC score	0.728137 (rank : 144)
Query Neighborhood Hits	2923	Target Neighborhood Hits	886	Shared Neighborhood Hits	803
SwissProt Accessions	Q8VHJ5, Q69ZI7	Gene names	Mark1, Emk3, Kiaa1477
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MARK1 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 1) (ELKL motif serine/threonine-protein kinase 3).

OPCM_HUMAN
θ value	4.58923e-20 (rank : 269)	NC score	0.489917 (rank : 857)
Query Neighborhood Hits	2923	Target Neighborhood Hits	332	Shared Neighborhood Hits	324
SwissProt Accessions	Q14982	Gene names	OPCML, OBCAM
Domain Architecture
Description	Opioid-binding protein/cell adhesion molecule precursor (OBCAM) (Opioid-binding cell adhesion molecule) (OPCML).

KPCE_MOUSE
θ value	5.99374e-20 (rank : 270)	NC score	0.708870 (rank : 268)
Query Neighborhood Hits	2923	Target Neighborhood Hits	906	Shared Neighborhood Hits	787
SwissProt Accessions	P16054	Gene names	Prkce, Pkce, Pkcea
Domain Architecture
Description	Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon).

KS6B1_HUMAN
θ value	5.99374e-20 (rank : 271)	NC score	0.724699 (rank : 161)
Query Neighborhood Hits	2923	Target Neighborhood Hits	850	Shared Neighborhood Hits	787
SwissProt Accessions	P23443	Gene names	RPS6KB1
Domain Architecture
Description	Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1) (Ribosomal protein S6 kinase I) (S6K) (S6K1) (70 kDa ribosomal protein S6 kinase 1) (p70 S6 kinase alpha) (p70(S6K)-alpha) (p70-S6K) (P70S6K) (p70-alpha).

KS6B1_MOUSE
θ value	5.99374e-20 (rank : 272)	NC score	0.724703 (rank : 160)
Query Neighborhood Hits	2923	Target Neighborhood Hits	849	Shared Neighborhood Hits	787
SwissProt Accessions	Q8BSK8, Q8CHX0	Gene names	Rps6kb1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1) (Ribosomal protein S6 kinase I) (S6K) (S6K1) (70 kDa ribosomal protein S6 kinase 1) (p70 S6 kinase alpha) (p70(S6K)-alpha) (p70-S6K) (P70S6K).

SGK3_MOUSE
θ value	5.99374e-20 (rank : 273)	NC score	0.715927 (rank : 212)
Query Neighborhood Hits	2923	Target Neighborhood Hits	882	Shared Neighborhood Hits	783
SwissProt Accessions	Q9ERE3, Q3UAY2	Gene names	Sgk3, Cisk, Sgkl
Domain Architecture
Description	Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid- regulated kinase-like) (Cytokine-independent survival kinase).

AURKB_HUMAN
θ value	7.82807e-20 (rank : 274)	NC score	0.735819 (rank : 86)
Query Neighborhood Hits	2923	Target Neighborhood Hits	847	Shared Neighborhood Hits	788
SwissProt Accessions	Q96GD4, O14630, O60446, O95083, Q96DV5, Q9UQ46	Gene names	AURKB, AIK2, AIM1, ARK2, STK12
Domain Architecture
Description	Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-B) (Aurora- and Ipl1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1- related kinase 2) (Aurora-related kinase 2) (STK-1).

MARK2_MOUSE
θ value	7.82807e-20 (rank : 275)	NC score	0.729063 (rank : 138)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1018	Shared Neighborhood Hits	854
SwissProt Accessions	Q05512, Q6PDR4, Q8BR95	Gene names	Mark2, Emk
Domain Architecture
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1).

NEK8_MOUSE
θ value	7.82807e-20 (rank : 276)	NC score	0.710680 (rank : 252)
Query Neighborhood Hits	2923	Target Neighborhood Hits	872	Shared Neighborhood Hits	793
SwissProt Accessions	Q91ZR4, Q3U498, Q9D685	Gene names	Nek8, Jck
Domain Architecture
Description	Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never in mitosis A-related kinase 8) (NimA-related protein kinase 8).

NEK8_HUMAN
θ value	1.33526e-19 (rank : 277)	NC score	0.710705 (rank : 251)
Query Neighborhood Hits	2923	Target Neighborhood Hits	872	Shared Neighborhood Hits	795
SwissProt Accessions	Q86SG6, Q2M1S6, Q8NDH1	Gene names	NEK8, JCK, NEK12A
Domain Architecture
Description	Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never in mitosis A-related kinase 8) (NimA-related protein kinase 8) (NIMA-related kinase 12a).

NTRI_MOUSE
θ value	1.33526e-19 (rank : 278)	NC score	0.489139 (rank : 860)
Query Neighborhood Hits	2923	Target Neighborhood Hits	342	Shared Neighborhood Hits	334
SwissProt Accessions	Q99PJ0	Gene names	Nt, Hnt
Domain Architecture
Description	Neurotrimin precursor.

PDPK1_HUMAN
θ value	1.33526e-19 (rank : 279)	NC score	0.730917 (rank : 124)
Query Neighborhood Hits	2923	Target Neighborhood Hits	851	Shared Neighborhood Hits	789
SwissProt Accessions	O15530	Gene names	PDPK1, PDK1
Domain Architecture
Description	3-phosphoinositide-dependent protein kinase 1 (EC 2.7.11.1) (hPDK1).

PAK1_MOUSE
θ value	1.74391e-19 (rank : 280)	NC score	0.715246 (rank : 222)
Query Neighborhood Hits	2923	Target Neighborhood Hits	878	Shared Neighborhood Hits	805
SwissProt Accessions	O88643	Gene names	Pak1, Paka
Domain Architecture
Description	Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (p21-activated kinase 1) (PAK-1) (P65-PAK) (Alpha-PAK) (CDC42/RAC effector kinase PAK-A).

PDPK1_MOUSE
θ value	1.74391e-19 (rank : 281)	NC score	0.730744 (rank : 125)
Query Neighborhood Hits	2923	Target Neighborhood Hits	852	Shared Neighborhood Hits	789
SwissProt Accessions	Q9Z2A0, Q9R1D8, Q9R215	Gene names	Pdpk1, Pdk1
Domain Architecture
Description	3-phosphoinositide-dependent protein kinase 1 (EC 2.7.11.1) (mPDK1).

PLK2_HUMAN
θ value	1.74391e-19 (rank : 282)	NC score	0.729694 (rank : 133)
Query Neighborhood Hits	2923	Target Neighborhood Hits	854	Shared Neighborhood Hits	785
SwissProt Accessions	Q9NYY3, O60679, Q96CV7, Q9UE61	Gene names	PLK2, SNK
Domain Architecture
Description	Serine/threonine-protein kinase PLK2 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-2) (Serine/threonine-protein kinase SNK) (Serum-inducible kinase).

CDKL3_MOUSE
θ value	2.27762e-19 (rank : 283)	NC score	0.714030 (rank : 228)
Query Neighborhood Hits	2923	Target Neighborhood Hits	857	Shared Neighborhood Hits	788
SwissProt Accessions	Q8BLF2, Q5M6W2, Q8BKR2, Q8BL49, Q8BVE0, Q8K134	Gene names	Cdkl3
Domain Architecture	No domain graphic available
Description	Cyclin-dependent kinase-like 3 (EC 2.7.11.22).

KPCT_HUMAN
θ value	2.27762e-19 (rank : 284)	NC score	0.712028 (rank : 241)
Query Neighborhood Hits	2923	Target Neighborhood Hits	897	Shared Neighborhood Hits	787
SwissProt Accessions	Q04759, Q3MJF1, Q64FY5, Q9H508, Q9H549	Gene names	PRKCQ, PRKCT
Domain Architecture
Description	Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta).

PKN3_MOUSE
θ value	2.27762e-19 (rank : 285)	NC score	0.715442 (rank : 220)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1009	Shared Neighborhood Hits	849
SwissProt Accessions	Q8K045	Gene names	Pkn3, Pknbeta
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

KPCE_HUMAN
θ value	2.97466e-19 (rank : 286)	NC score	0.708852 (rank : 269)
Query Neighborhood Hits	2923	Target Neighborhood Hits	906	Shared Neighborhood Hits	790
SwissProt Accessions	Q02156, Q53SL4, Q53SM5, Q9UE81	Gene names	PRKCE, PKCE
Domain Architecture
Description	Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon).

KPCG_MOUSE
θ value	2.97466e-19 (rank : 287)	NC score	0.690519 (rank : 394)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1123	Shared Neighborhood Hits	795
SwissProt Accessions	P63318, P05697	Gene names	Prkcg, Pkcc, Pkcg, Prkcc
Domain Architecture	No domain graphic available
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

PLK2_MOUSE
θ value	2.97466e-19 (rank : 288)	NC score	0.729383 (rank : 136)
Query Neighborhood Hits	2923	Target Neighborhood Hits	849	Shared Neighborhood Hits	784
SwissProt Accessions	P53351	Gene names	Plk2, Snk
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PLK2 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-2) (Serine/threonine-protein kinase SNK) (Serum-inducible kinase).

STK4_MOUSE
θ value	2.97466e-19 (rank : 289)	NC score	0.702307 (rank : 307)
Query Neighborhood Hits	2923	Target Neighborhood Hits	873	Shared Neighborhood Hits	792
SwissProt Accessions	Q9JI11	Gene names	Stk4, Mst1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 4 (EC 2.7.11.1) (STE20-like kinase MST1) (MST-1) (Mammalian STE20-like protein kinase 1).

KPCG_HUMAN
θ value	3.88503e-19 (rank : 290)	NC score	0.690288 (rank : 396)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1126	Shared Neighborhood Hits	797
SwissProt Accessions	P05129	Gene names	PRKCG, PKCG
Domain Architecture
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

MARK4_HUMAN
θ value	3.88503e-19 (rank : 291)	NC score	0.730068 (rank : 129)
Query Neighborhood Hits	2923	Target Neighborhood Hits	886	Shared Neighborhood Hits	805
SwissProt Accessions	Q96L34, Q8NG37, Q96JG7, Q96SQ2, Q9BYD8	Gene names	MARK4, KIAA1860, MARKL1
Domain Architecture
Description	MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase-like 1).

MARK4_MOUSE
θ value	3.88503e-19 (rank : 292)	NC score	0.729839 (rank : 130)
Query Neighborhood Hits	2923	Target Neighborhood Hits	898	Shared Neighborhood Hits	807
SwissProt Accessions	Q8CIP4, Q80T81	Gene names	Mark4, Kiaa1860
Domain Architecture	No domain graphic available
Description	MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1).

CDKL4_MOUSE
θ value	5.07402e-19 (rank : 293)	NC score	0.708639 (rank : 272)
Query Neighborhood Hits	2923	Target Neighborhood Hits	833	Shared Neighborhood Hits	779
SwissProt Accessions	Q3TZA2	Gene names	Cdkl4
Domain Architecture	No domain graphic available
Description	Cyclin-dependent kinase-like 4 (EC 2.7.11.22).

DYRK4_HUMAN
θ value	5.07402e-19 (rank : 294)	NC score	0.677278 (rank : 469)
Query Neighborhood Hits	2923	Target Neighborhood Hits	750	Shared Neighborhood Hits	733
SwissProt Accessions	Q9NR20, Q8NEF2, Q92631	Gene names	DYRK4
Domain Architecture	No domain graphic available
Description	Dual specificity tyrosine-phosphorylation-regulated kinase 4 (EC 2.7.12.1).

KAPCG_HUMAN
θ value	5.07402e-19 (rank : 295)	NC score	0.728734 (rank : 141)
Query Neighborhood Hits	2923	Target Neighborhood Hits	845	Shared Neighborhood Hits	788
SwissProt Accessions	P22612, O60850, Q86YI1	Gene names	PRKACG
Domain Architecture
Description	cAMP-dependent protein kinase, gamma-catalytic subunit (EC 2.7.11.11) (PKA C-gamma).

CDKL3_HUMAN
θ value	6.62687e-19 (rank : 296)	NC score	0.713429 (rank : 235)
Query Neighborhood Hits	2923	Target Neighborhood Hits	853	Shared Neighborhood Hits	790
SwissProt Accessions	Q8IVW4, Q9P114	Gene names	CDKL3, NKIAMRE
Domain Architecture	No domain graphic available
Description	Cyclin-dependent kinase-like 3 (EC 2.7.11.22) (Serine/threonine protein kinase NKIAMRE).

GRK5_MOUSE
θ value	8.65492e-19 (rank : 297)	NC score	0.716285 (rank : 208)
Query Neighborhood Hits	2923	Target Neighborhood Hits	823	Shared Neighborhood Hits	769
SwissProt Accessions	Q8VEB1, O70292, O70297	Gene names	Grk5, Gprk5
Domain Architecture
Description	G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK5).

GRK6_HUMAN
θ value	8.65492e-19 (rank : 298)	NC score	0.716050 (rank : 209)
Query Neighborhood Hits	2923	Target Neighborhood Hits	823	Shared Neighborhood Hits	775
SwissProt Accessions	P43250, O60541, Q13652	Gene names	GRK6, GPRK6
Domain Architecture
Description	G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK6).

PAK4_HUMAN
θ value	8.65492e-19 (rank : 299)	NC score	0.720797 (rank : 181)
Query Neighborhood Hits	2923	Target Neighborhood Hits	924	Shared Neighborhood Hits	829
SwissProt Accessions	O96013, Q8N4E1, Q8NCH5, Q8NDE3, Q9BU33, Q9ULS8	Gene names	PAK4, KIAA1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

PAK4_MOUSE
θ value	8.65492e-19 (rank : 300)	NC score	0.719206 (rank : 188)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1098	Shared Neighborhood Hits	866
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

CEAM1_MOUSE
θ value	1.13037e-18 (rank : 301)	NC score	0.415362 (rank : 927)
Query Neighborhood Hits	2923	Target Neighborhood Hits	326	Shared Neighborhood Hits	296
SwissProt Accessions	P31809	Gene names	Ceacam1, Bgp, Bgp1, Bgpd
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 1 precursor (Biliary glycoprotein 1) (BGP-1) (Murine hepatitis virus receptor) (MHV-R) (Biliary glycoprotein D).

CDKL2_HUMAN
θ value	1.47631e-18 (rank : 302)	NC score	0.708724 (rank : 271)
Query Neighborhood Hits	2923	Target Neighborhood Hits	838	Shared Neighborhood Hits	782
SwissProt Accessions	Q92772	Gene names	CDKL2
Domain Architecture	No domain graphic available
Description	Cyclin-dependent kinase-like 2 (EC 2.7.11.22) (Serine/threonine- protein kinase KKIAMRE) (Protein kinase p56 KKIAMRE).

KIRR3_HUMAN
θ value	1.47631e-18 (rank : 303)	NC score	0.430132 (rank : 907)
Query Neighborhood Hits	2923	Target Neighborhood Hits	302	Shared Neighborhood Hits	278
SwissProt Accessions	Q8IZU9, Q6UWJ9, Q6UWL5, Q96JG0	Gene names	KIRREL3, KIAA1867, NEPH2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 3 precursor (Kin of irregular chiasm-like protein 3) (Nephrin-like 2).

FGRL1_HUMAN
θ value	1.92812e-18 (rank : 304)	NC score	0.496295 (rank : 846)
Query Neighborhood Hits	2923	Target Neighborhood Hits	335	Shared Neighborhood Hits	310
SwissProt Accessions	Q8N441, Q6PJN1, Q9BXN7, Q9H4D7	Gene names	FGFRL1, FGFR5, FHFR
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5) (FGFR-like protein) (FGF homologous factor receptor).

GRK5_HUMAN
θ value	1.92812e-18 (rank : 305)	NC score	0.715859 (rank : 214)
Query Neighborhood Hits	2923	Target Neighborhood Hits	819	Shared Neighborhood Hits	769
SwissProt Accessions	P34947	Gene names	GRK5, GPRK5
Domain Architecture
Description	G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK5).

KPCD_MOUSE
θ value	1.92812e-18 (rank : 306)	NC score	0.710057 (rank : 259)
Query Neighborhood Hits	2923	Target Neighborhood Hits	888	Shared Neighborhood Hits	783
SwissProt Accessions	P28867, Q91V85, Q9Z333	Gene names	Prkcd, Pkcd
Domain Architecture
Description	Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta).

KPCL_MOUSE
θ value	1.92812e-18 (rank : 307)	NC score	0.710841 (rank : 249)
Query Neighborhood Hits	2923	Target Neighborhood Hits	891	Shared Neighborhood Hits	779
SwissProt Accessions	P23298	Gene names	Prkch, Pkch
Domain Architecture
Description	Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta) (PKC-L).

PRKY_HUMAN
θ value	1.92812e-18 (rank : 308)	NC score	0.729091 (rank : 137)
Query Neighborhood Hits	2923	Target Neighborhood Hits	844	Shared Neighborhood Hits	785
SwissProt Accessions	O43930, O15348, O15349	Gene names	PRKY
Domain Architecture
Description	Serine/threonine-protein kinase PRKY (EC 2.7.11.1).

STK3_MOUSE
θ value	1.92812e-18 (rank : 309)	NC score	0.702880 (rank : 299)
Query Neighborhood Hits	2923	Target Neighborhood Hits	869	Shared Neighborhood Hits	795
SwissProt Accessions	Q9JI10, Q60877, Q80UG4, Q8CI58	Gene names	Stk3, Mess1, Mst2
Domain Architecture
Description	Serine/threonine-protein kinase 3 (EC 2.7.11.1) (STE20-like kinase MST2) (MST-2) (Mammalian STE20-like protein kinase 2).

FGRL1_MOUSE
θ value	2.5182e-18 (rank : 310)	NC score	0.494183 (rank : 850)
Query Neighborhood Hits	2923	Target Neighborhood Hits	325	Shared Neighborhood Hits	311
SwissProt Accessions	Q91V87, Q920C2, Q920C3	Gene names	Fgfrl1, Fgfr5
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5).

GRK4_HUMAN
θ value	2.5182e-18 (rank : 311)	NC score	0.712897 (rank : 237)
Query Neighborhood Hits	2923	Target Neighborhood Hits	822	Shared Neighborhood Hits	775
SwissProt Accessions	P32298, O00641, O00642, Q13293, Q13294, Q13295, Q14453, Q14725, Q15313, Q15314, Q15315, Q15316	Gene names	GRK4, GPRK2L, GPRK4
Domain Architecture
Description	G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK4) (ITI1).

KAPCB_MOUSE
θ value	2.5182e-18 (rank : 312)	NC score	0.726688 (rank : 150)
Query Neighborhood Hits	2923	Target Neighborhood Hits	836	Shared Neighborhood Hits	785
SwissProt Accessions	P68181, P05206, Q3TQH5, Q3UDD0, Q3UTH5	Gene names	Prkacb, Pkacb
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase, beta-catalytic subunit (EC 2.7.11.11) (PKA C-beta).

KIRR3_MOUSE
θ value	2.5182e-18 (rank : 313)	NC score	0.426490 (rank : 913)
Query Neighborhood Hits	2923	Target Neighborhood Hits	292	Shared Neighborhood Hits	268
SwissProt Accessions	Q8BR86, Q6P555, Q810H3, Q8BGQ5, Q8BRS8	Gene names	Kirrel3, Kiaa1867
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 3 precursor (Kin of irregular chiasm-like protein 3).

KPCA_HUMAN
θ value	2.5182e-18 (rank : 314)	NC score	0.695170 (rank : 347)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1070	Shared Neighborhood Hits	794
SwissProt Accessions	P17252, Q15137, Q96RE4	Gene names	PRKCA, PKCA, PRKACA
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

KPCA_MOUSE
θ value	2.5182e-18 (rank : 315)	NC score	0.696253 (rank : 342)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1067	Shared Neighborhood Hits	791
SwissProt Accessions	P20444	Gene names	Prkca, Pkca
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

KS6B2_MOUSE
θ value	2.5182e-18 (rank : 316)	NC score	0.723299 (rank : 165)
Query Neighborhood Hits	2923	Target Neighborhood Hits	871	Shared Neighborhood Hits	799
SwissProt Accessions	Q9Z1M4	Gene names	Rps6kb2
Domain Architecture
Description	Ribosomal protein S6 kinase beta-2 (EC 2.7.11.1) (S6K-beta 2) (70 kDa ribosomal protein S6 kinase 2) (p70-S6KB) (p70 ribosomal S6 kinase beta) (p70 S6Kbeta) (S6K2).

CDKL4_HUMAN
θ value	3.28887e-18 (rank : 317)	NC score	0.706468 (rank : 284)
Query Neighborhood Hits	2923	Target Neighborhood Hits	828	Shared Neighborhood Hits	775
SwissProt Accessions	Q5MAI5	Gene names	CDKL4
Domain Architecture	No domain graphic available
Description	Cyclin-dependent kinase-like 4 (EC 2.7.11.22).

CTRO_MOUSE
θ value	3.28887e-18 (rank : 318)	NC score	0.634245 (rank : 582)
Query Neighborhood Hits	2923	Target Neighborhood Hits	2344	Shared Neighborhood Hits	1261
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

NEK4_MOUSE
θ value	3.28887e-18 (rank : 319)	NC score	0.717770 (rank : 202)
Query Neighborhood Hits	2923	Target Neighborhood Hits	899	Shared Neighborhood Hits	808
SwissProt Accessions	Q9Z1J2, O35673, Q9R1J1	Gene names	Nek4, Stk2
Domain Architecture
Description	Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2).

STK4_HUMAN
θ value	3.28887e-18 (rank : 320)	NC score	0.702087 (rank : 308)
Query Neighborhood Hits	2923	Target Neighborhood Hits	870	Shared Neighborhood Hits	791
SwissProt Accessions	Q13043, Q15802, Q4G156, Q5H982, Q6PD60, Q9BR32, Q9NTZ4	Gene names	STK4, MST1
Domain Architecture
Description	Serine/threonine-protein kinase 4 (EC 2.7.11.1) (STE20-like kinase MST1) (MST-1) (Mammalian STE20-like protein kinase 1) (Serine/threonine-protein kinase Krs-2).

CSK21_HUMAN
θ value	4.29542e-18 (rank : 321)	NC score	0.694976 (rank : 350)
Query Neighborhood Hits	2923	Target Neighborhood Hits	772	Shared Neighborhood Hits	741
SwissProt Accessions	P68400, P19138, P20426, Q14013	Gene names	CSNK2A1, CK2A1
Domain Architecture	No domain graphic available
Description	Casein kinase II subunit alpha (EC 2.7.11.1) (CK II).

CTRO_HUMAN
θ value	4.29542e-18 (rank : 322)	NC score	0.648527 (rank : 550)
Query Neighborhood Hits	2923	Target Neighborhood Hits	2092	Shared Neighborhood Hits	1195
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

GRK6_MOUSE
θ value	4.29542e-18 (rank : 323)	NC score	0.715293 (rank : 221)
Query Neighborhood Hits	2923	Target Neighborhood Hits	820	Shared Neighborhood Hits	773
SwissProt Accessions	O70293, O70294, O70295	Gene names	Grk6, Gprk6
Domain Architecture
Description	G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK6).

STK3_HUMAN
θ value	4.29542e-18 (rank : 324)	NC score	0.702329 (rank : 306)
Query Neighborhood Hits	2923	Target Neighborhood Hits	861	Shared Neighborhood Hits	794
SwissProt Accessions	Q13188, Q15445, Q15801, Q96FM6	Gene names	STK3, MST2
Domain Architecture
Description	Serine/threonine-protein kinase 3 (EC 2.7.11.1) (STE20-like kinase MST2) (MST-2) (Mammalian STE20-like protein kinase 2) (Serine/threonine-protein kinase Krs-1).

GRK4_MOUSE
θ value	5.60996e-18 (rank : 325)	NC score	0.712535 (rank : 238)
Query Neighborhood Hits	2923	Target Neighborhood Hits	808	Shared Neighborhood Hits	765
SwissProt Accessions	O70291	Gene names	Grk4, Gprk2l
Domain Architecture
Description	G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK4).

KAPCA_MOUSE
θ value	5.60996e-18 (rank : 326)	NC score	0.727505 (rank : 147)
Query Neighborhood Hits	2923	Target Neighborhood Hits	836	Shared Neighborhood Hits	786
SwissProt Accessions	P05132, Q9JID0	Gene names	Prkaca, Pkaca
Domain Architecture
Description	cAMP-dependent protein kinase, alpha-catalytic subunit (EC 2.7.11.11) (PKA C-alpha).

KAPCB_HUMAN
θ value	5.60996e-18 (rank : 327)	NC score	0.726827 (rank : 149)
Query Neighborhood Hits	2923	Target Neighborhood Hits	837	Shared Neighborhood Hits	785
SwissProt Accessions	P22694, Q59GC0, Q5BNE9, Q5BNF0, Q5BNF1, Q5BNF2, Q5BNF3, Q5CZ92, Q5T1K3, Q7Z3M1, Q8IYR5, Q8IZQ0	Gene names	PRKACB
Domain Architecture
Description	cAMP-dependent protein kinase, beta-catalytic subunit (EC 2.7.11.11) (PKA C-beta).

LSAMP_MOUSE
θ value	5.60996e-18 (rank : 328)	NC score	0.494641 (rank : 848)
Query Neighborhood Hits	2923	Target Neighborhood Hits	344	Shared Neighborhood Hits	336
SwissProt Accessions	Q8BLK3	Gene names	Lsamp
Domain Architecture	No domain graphic available
Description	Limbic system-associated membrane protein precursor (LSAMP).

ROCK1_HUMAN
θ value	5.60996e-18 (rank : 329)	NC score	0.648162 (rank : 554)
Query Neighborhood Hits	2923	Target Neighborhood Hits	2000	Shared Neighborhood Hits	1175
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

ROCK1_MOUSE
θ value	5.60996e-18 (rank : 330)	NC score	0.637679 (rank : 577)
Query Neighborhood Hits	2923	Target Neighborhood Hits	2126	Shared Neighborhood Hits	1209
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

TENR_HUMAN
θ value	5.60996e-18 (rank : 331)	NC score	0.197371 (rank : 1086)
Query Neighborhood Hits	2923	Target Neighborhood Hits	526	Shared Neighborhood Hits	209
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

CDKL1_MOUSE
θ value	7.32683e-18 (rank : 332)	NC score	0.710595 (rank : 253)
Query Neighborhood Hits	2923	Target Neighborhood Hits	829	Shared Neighborhood Hits	776
SwissProt Accessions	Q8CEQ0	Gene names	Cdkl1
Domain Architecture	No domain graphic available
Description	Cyclin-dependent kinase-like 1 (EC 2.7.11.22).

KS6B2_HUMAN
θ value	7.32683e-18 (rank : 333)	NC score	0.724365 (rank : 162)
Query Neighborhood Hits	2923	Target Neighborhood Hits	858	Shared Neighborhood Hits	796
SwissProt Accessions	Q9UBS0, O94809, Q9UEC1	Gene names	RPS6KB2, STK14B
Domain Architecture
Description	Ribosomal protein S6 kinase beta-2 (EC 2.7.11.1) (S6K2) (70 kDa ribosomal protein S6 kinase 2) (p70-S6KB) (p70 ribosomal S6 kinase beta) (p70 S6Kbeta) (p70 S6 kinase beta) (S6K-beta) (p70-beta) (S6 kinase-related kinase) (SRK) (Serine/threonine-protein kinase 14 beta).

M3K4_HUMAN
θ value	7.32683e-18 (rank : 334)	NC score	0.710245 (rank : 257)
Query Neighborhood Hits	2923	Target Neighborhood Hits	911	Shared Neighborhood Hits	817
SwissProt Accessions	Q9Y6R4, Q92612	Gene names	MAP3K4, KIAA0213, MAPKKK4, MEKK4, MTK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4) (MAP three kinase 1).

KIRR2_MOUSE
θ value	9.56915e-18 (rank : 335)	NC score	0.445180 (rank : 901)
Query Neighborhood Hits	2923	Target Neighborhood Hits	326	Shared Neighborhood Hits	295
SwissProt Accessions	Q7TSU7, Q7TQ98	Gene names	Kirrel2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2).

KPCL_HUMAN
θ value	9.56915e-18 (rank : 336)	NC score	0.709487 (rank : 264)
Query Neighborhood Hits	2923	Target Neighborhood Hits	887	Shared Neighborhood Hits	778
SwissProt Accessions	P24723, Q16246	Gene names	PRKCH, PKCL
Domain Architecture
Description	Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta) (PKC-L).

NEK11_MOUSE
θ value	9.56915e-18 (rank : 337)	NC score	0.715223 (rank : 223)
Query Neighborhood Hits	2923	Target Neighborhood Hits	875	Shared Neighborhood Hits	798
SwissProt Accessions	Q8C0Q4, Q8BLS6, Q8BW62	Gene names	Nek11
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11).

KPCD_HUMAN
θ value	1.24977e-17 (rank : 338)	NC score	0.710063 (rank : 258)
Query Neighborhood Hits	2923	Target Neighborhood Hits	900	Shared Neighborhood Hits	785
SwissProt Accessions	Q05655, Q15144	Gene names	PRKCD
Domain Architecture
Description	Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta).

MARK3_HUMAN
θ value	1.24977e-17 (rank : 339)	NC score	0.726464 (rank : 153)
Query Neighborhood Hits	2923	Target Neighborhood Hits	893	Shared Neighborhood Hits	803
SwissProt Accessions	P27448, O60219, Q8TB41, Q8WX83, Q96RG1, Q9UMY9, Q9UN34	Gene names	MARK3, CTAK1
Domain Architecture
Description	MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (Cdc25C- associated protein kinase 1) (cTAK1) (C-TAK1) (Serine/threonine protein kinase p78) (Ser/Thr protein kinase PAR-1) (Protein kinase STK10).

NEK4_HUMAN
θ value	1.24977e-17 (rank : 340)	NC score	0.716817 (rank : 206)
Query Neighborhood Hits	2923	Target Neighborhood Hits	883	Shared Neighborhood Hits	801
SwissProt Accessions	P51957	Gene names	NEK4, STK2
Domain Architecture
Description	Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2) (Serine/threonine-protein kinase NRK2).

ROCK2_HUMAN
θ value	1.24977e-17 (rank : 341)	NC score	0.651278 (rank : 547)
Query Neighborhood Hits	2923	Target Neighborhood Hits	2073	Shared Neighborhood Hits	1187
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

CSK21_MOUSE
θ value	1.63225e-17 (rank : 342)	NC score	0.695153 (rank : 348)
Query Neighborhood Hits	2923	Target Neighborhood Hits	770	Shared Neighborhood Hits	741
SwissProt Accessions	Q60737	Gene names	Csnk2a1, Ckiia
Domain Architecture
Description	Casein kinase II subunit alpha (EC 2.7.11.1) (CK II).

LSAMP_HUMAN
θ value	1.63225e-17 (rank : 343)	NC score	0.494779 (rank : 847)
Query Neighborhood Hits	2923	Target Neighborhood Hits	347	Shared Neighborhood Hits	339
SwissProt Accessions	Q13449, Q8IV49	Gene names	LSAMP, LAMP
Domain Architecture
Description	Limbic system-associated membrane protein precursor (LSAMP).

KAPCA_HUMAN
θ value	2.13179e-17 (rank : 344)	NC score	0.726984 (rank : 148)
Query Neighborhood Hits	2923	Target Neighborhood Hits	838	Shared Neighborhood Hits	786
SwissProt Accessions	P17612, Q9H2Y0, Q9NRB4, Q9NRH9	Gene names	PRKACA, PKACA
Domain Architecture
Description	cAMP-dependent protein kinase, alpha-catalytic subunit (EC 2.7.11.11) (PKA C-alpha).

CDC2_MOUSE
θ value	2.7842e-17 (rank : 345)	NC score	0.701189 (rank : 310)
Query Neighborhood Hits	2923	Target Neighborhood Hits	838	Shared Neighborhood Hits	784
SwissProt Accessions	P11440, P70337, Q3TI12	Gene names	Cdc2, Cdc2a
Domain Architecture
Description	Cell division control protein 2 homolog (EC 2.7.11.22) (EC 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1).

TSSK1_MOUSE
θ value	2.7842e-17 (rank : 346)	NC score	0.729777 (rank : 132)
Query Neighborhood Hits	2923	Target Neighborhood Hits	835	Shared Neighborhood Hits	776
SwissProt Accessions	Q61241	Gene names	Tssk1, Stk22a
Domain Architecture
Description	Testis-specific serine/threonine-protein kinase 1 (EC 2.7.11.1) (TSSK- 1) (Testis-specific kinase 1) (TSK-1) (Serine/threonine-protein kinase 22A).

TSSK3_MOUSE
θ value	2.7842e-17 (rank : 347)	NC score	0.726242 (rank : 155)
Query Neighborhood Hits	2923	Target Neighborhood Hits	806	Shared Neighborhood Hits	757
SwissProt Accessions	Q9D2E1, Q9JL98	Gene names	Tssk3, Stk22c, Stk22d
Domain Architecture
Description	Testis-specific serine/threonine-protein kinase 3 (EC 2.7.11.1) (TSSK- 3) (Testis-specific kinase 3) (TSK-3) (Serine/threonine-protein kinase 22C).

CDKL1_HUMAN
θ value	3.63628e-17 (rank : 348)	NC score	0.710447 (rank : 255)
Query Neighborhood Hits	2923	Target Neighborhood Hits	830	Shared Neighborhood Hits	776
SwissProt Accessions	Q00532, Q6QUA0	Gene names	CDKL1
Domain Architecture
Description	Cyclin-dependent kinase-like 1 (EC 2.7.11.22) (Serine/threonine- protein kinase KKIALRE) (Protein kinase p42 KKIALRE).

M3K4_MOUSE
θ value	3.63628e-17 (rank : 349)	NC score	0.708472 (rank : 274)
Query Neighborhood Hits	2923	Target Neighborhood Hits	924	Shared Neighborhood Hits	817
SwissProt Accessions	O08648, O08649, O70124	Gene names	Map3k4, Mekk4
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4).

TSSK3_HUMAN
θ value	3.63628e-17 (rank : 350)	NC score	0.726181 (rank : 156)
Query Neighborhood Hits	2923	Target Neighborhood Hits	806	Shared Neighborhood Hits	756
SwissProt Accessions	Q96PN8	Gene names	TSSK3, SPOGA3, STK22C
Domain Architecture
Description	Testis-specific serine/threonine-protein kinase 3 (EC 2.7.11.1) (TSSK- 3) (Testis-specific kinase 3) (TSK-3) (Serine/threonine-protein kinase 22C).

NEK3_HUMAN
θ value	4.74913e-17 (rank : 351)	NC score	0.721877 (rank : 173)
Query Neighborhood Hits	2923	Target Neighborhood Hits	865	Shared Neighborhood Hits	801
SwissProt Accessions	P51956, Q8WUN5	Gene names	NEK3
Domain Architecture
Description	Serine/threonine-protein kinase Nek3 (EC 2.7.11.1) (NimA-related protein kinase 3) (HSPK 36).

ST32B_MOUSE
θ value	6.20254e-17 (rank : 352)	NC score	0.718571 (rank : 196)
Query Neighborhood Hits	2923	Target Neighborhood Hits	828	Shared Neighborhood Hits	779
SwissProt Accessions	Q9JJX8, Q7TMD3, Q8C4E0	Gene names	Stk32b, Stk32
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 32B (EC 2.7.11.1).

NEK11_HUMAN
θ value	8.10077e-17 (rank : 353)	NC score	0.713498 (rank : 233)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1043	Shared Neighborhood Hits	888
SwissProt Accessions	Q8NG66, Q5JPC0, Q8NG65, Q8TBY1, Q9H5F4	Gene names	NEK11
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11).

CDK5_HUMAN
θ value	1.058e-16 (rank : 354)	NC score	0.693038 (rank : 368)
Query Neighborhood Hits	2923	Target Neighborhood Hits	826	Shared Neighborhood Hits	771
SwissProt Accessions	Q00535	Gene names	CDK5
Domain Architecture
Description	Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE).

CDK5_MOUSE
θ value	1.058e-16 (rank : 355)	NC score	0.692913 (rank : 370)
Query Neighborhood Hits	2923	Target Neighborhood Hits	826	Shared Neighborhood Hits	771
SwissProt Accessions	P49615	Gene names	Cdk5, Crk6
Domain Architecture
Description	Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) (CRK6).

DYRK3_HUMAN
θ value	1.058e-16 (rank : 356)	NC score	0.686463 (rank : 420)
Query Neighborhood Hits	2923	Target Neighborhood Hits	798	Shared Neighborhood Hits	759
SwissProt Accessions	O43781	Gene names	DYRK3
Domain Architecture
Description	Dual specificity tyrosine-phosphorylation-regulated kinase 3 (EC 2.7.12.1).

KPCB_HUMAN
θ value	1.058e-16 (rank : 357)	NC score	0.691202 (rank : 385)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1121	Shared Neighborhood Hits	795
SwissProt Accessions	P05771, O43744, P05127, Q15138, Q93060, Q9UE49, Q9UE50, Q9UEH8, Q9UJ30, Q9UJ33	Gene names	PRKCB1, PKCB, PRKCB
Domain Architecture
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

KPCB_MOUSE
θ value	1.058e-16 (rank : 358)	NC score	0.691609 (rank : 382)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1117	Shared Neighborhood Hits	794
SwissProt Accessions	P68404, P04410, P04411	Gene names	Prkcb1, Pkcb, Prkcb
Domain Architecture	No domain graphic available
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

ROCK2_MOUSE
θ value	1.058e-16 (rank : 359)	NC score	0.645785 (rank : 559)
Query Neighborhood Hits	2923	Target Neighborhood Hits	2072	Shared Neighborhood Hits	1200
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

CDC2_HUMAN
θ value	1.38178e-16 (rank : 360)	NC score	0.701881 (rank : 309)
Query Neighborhood Hits	2923	Target Neighborhood Hits	842	Shared Neighborhood Hits	787
SwissProt Accessions	P06493, O60764	Gene names	CDC2
Domain Architecture
Description	Cell division control protein 2 homolog (EC 2.7.11.22) (EC 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1).

PLK1_MOUSE
θ value	1.38178e-16 (rank : 361)	NC score	0.732993 (rank : 106)
Query Neighborhood Hits	2923	Target Neighborhood Hits	849	Shared Neighborhood Hits	784
SwissProt Accessions	Q07832	Gene names	Plk1, Plk
Domain Architecture
Description	Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13).

VGFR2_MOUSE
θ value	1.38178e-16 (rank : 362)	NC score	0.681338 (rank : 454)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1089	Shared Neighborhood Hits	1010
SwissProt Accessions	P35918	Gene names	Kdr, Flk-1, Flk1
Domain Architecture
Description	Vascular endothelial growth factor receptor 2 precursor (EC 2.7.10.1) (VEGFR-2) (Protein-tyrosine kinase receptor flk-1) (Fetal liver kinase 1) (Kinase NYK) (CD309 antigen).

HUNK_MOUSE
θ value	1.80466e-16 (rank : 363)	NC score	0.734602 (rank : 91)
Query Neighborhood Hits	2923	Target Neighborhood Hits	874	Shared Neighborhood Hits	797
SwissProt Accessions	O88866	Gene names	Hunk, Makv
Domain Architecture
Description	Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (Serine/threonine-protein kinase MAK-V).

MK15_HUMAN
θ value	1.80466e-16 (rank : 364)	NC score	0.698763 (rank : 327)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1038	Shared Neighborhood Hits	836
SwissProt Accessions	Q8TD08, Q2TCF9, Q8N362	Gene names	MAPK15, ERK8
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 8).

CSK22_HUMAN
θ value	2.35696e-16 (rank : 365)	NC score	0.689700 (rank : 401)
Query Neighborhood Hits	2923	Target Neighborhood Hits	758	Shared Neighborhood Hits	730
SwissProt Accessions	P19784	Gene names	CSNK2A2, CK2A2
Domain Architecture
Description	Casein kinase II subunit alpha' (EC 2.7.11.1) (CK II).

MOK_HUMAN
θ value	2.35696e-16 (rank : 366)	NC score	0.693922 (rank : 355)
Query Neighborhood Hits	2923	Target Neighborhood Hits	807	Shared Neighborhood Hits	763
SwissProt Accessions	Q9UQ07, Q92790, Q93067	Gene names	RAGE, MOK, RAGE1
Domain Architecture
Description	MAPK/MAK/MRK overlapping kinase (EC 2.7.11.22) (MOK protein kinase) (Renal tumor antigen 1) (RAGE-1).

PCTK3_MOUSE
θ value	2.35696e-16 (rank : 367)	NC score	0.693315 (rank : 363)
Query Neighborhood Hits	2923	Target Neighborhood Hits	834	Shared Neighborhood Hits	776
SwissProt Accessions	Q04899	Gene names	Pctk3
Domain Architecture
Description	Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22) (PCTAIRE- motif protein kinase 3).

PLK1_HUMAN
θ value	2.35696e-16 (rank : 368)	NC score	0.732543 (rank : 114)
Query Neighborhood Hits	2923	Target Neighborhood Hits	849	Shared Neighborhood Hits	784
SwissProt Accessions	P53350, Q15153, Q99746	Gene names	PLK1, PLK
Domain Architecture
Description	Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13).

CSK22_MOUSE
θ value	3.07829e-16 (rank : 369)	NC score	0.689735 (rank : 400)
Query Neighborhood Hits	2923	Target Neighborhood Hits	758	Shared Neighborhood Hits	730
SwissProt Accessions	O54833	Gene names	Csnk2a2
Domain Architecture
Description	Casein kinase II subunit alpha' (EC 2.7.11.1) (CK II).

KKCC1_HUMAN
θ value	3.07829e-16 (rank : 370)	NC score	0.732338 (rank : 117)
Query Neighborhood Hits	2923	Target Neighborhood Hits	858	Shared Neighborhood Hits	786
SwissProt Accessions	Q8N5S9, Q9BQH3	Gene names	CAMKK1, CAMKKA
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase kinase 1 (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-kinase kinase alpha) (CaM-KK alpha) (CaMKK alpha) (CaMKK 1) (CaM-kinase IV kinase).

KKCC1_MOUSE
θ value	3.07829e-16 (rank : 371)	NC score	0.732635 (rank : 113)
Query Neighborhood Hits	2923	Target Neighborhood Hits	866	Shared Neighborhood Hits	793
SwissProt Accessions	Q8VBY2, Q9R054	Gene names	Camkk1, Camkk
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase kinase 1 (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-kinase kinase alpha) (CaM-KK alpha) (CaMKK alpha) (CaMKK 1) (CaM-kinase IV kinase).

KPCI_MOUSE
θ value	3.07829e-16 (rank : 372)	NC score	0.709994 (rank : 260)
Query Neighborhood Hits	2923	Target Neighborhood Hits	888	Shared Neighborhood Hits	793
SwissProt Accessions	Q62074	Gene names	Prkci, Pkcl
Domain Architecture
Description	Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota) (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota).

NEK9_HUMAN
θ value	3.07829e-16 (rank : 373)	NC score	0.699498 (rank : 321)
Query Neighborhood Hits	2923	Target Neighborhood Hits	900	Shared Neighborhood Hits	800
SwissProt Accessions	Q8TD19, Q52LK6, Q8NCN0, Q8TCY4, Q9UPI4, Q9Y6S4, Q9Y6S5, Q9Y6S6	Gene names	NEK9, KIAA1995, NEK8, NERCC
Domain Architecture
Description	Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (NimA-related protein kinase 9) (Never in mitosis A-related kinase 9) (Nercc1 kinase) (NIMA-related kinase 8) (Nek8).

PLK3_HUMAN
θ value	3.07829e-16 (rank : 374)	NC score	0.731137 (rank : 122)
Query Neighborhood Hits	2923	Target Neighborhood Hits	865	Shared Neighborhood Hits	791
SwissProt Accessions	Q9H4B4, Q15767, Q96CV1	Gene names	PLK3, CNK, FNK, PRK
Domain Architecture
Description	Serine/threonine-protein kinase PLK3 (EC 2.7.11.21) (Polo-like kinase 3) (PLK-3) (Cytokine-inducible serine/threonine-protein kinase) (FGF- inducible kinase) (Proliferation-related kinase).

RK_MOUSE
θ value	3.07829e-16 (rank : 375)	NC score	0.714099 (rank : 226)
Query Neighborhood Hits	2923	Target Neighborhood Hits	829	Shared Neighborhood Hits	777
SwissProt Accessions	Q9WVL4	Gene names	Grk1, Rhok
Domain Architecture
Description	Rhodopsin kinase precursor (EC 2.7.11.14) (RK) (G protein-coupled receptor kinase 1).

TSSK2_HUMAN
θ value	3.07829e-16 (rank : 376)	NC score	0.729546 (rank : 134)
Query Neighborhood Hits	2923	Target Neighborhood Hits	826	Shared Neighborhood Hits	771
SwissProt Accessions	Q96PF2, Q8IY55	Gene names	TSSK2, DGSG, SPOGA2, STK22B
Domain Architecture
Description	Testis-specific serine/threonine-protein kinase 2 (EC 2.7.11.1) (TSSK- 2) (Testis-specific kinase 2) (TSK-2) (Serine/threonine-protein kinase 22B) (DiGeorge syndrome protein G).

ST32C_HUMAN
θ value	4.02038e-16 (rank : 377)	NC score	0.718647 (rank : 195)
Query Neighborhood Hits	2923	Target Neighborhood Hits	832	Shared Neighborhood Hits	778
SwissProt Accessions	Q86UX6, Q5T0Q5, Q86UE1	Gene names	STK32C
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 32C (EC 2.7.11.1) (PKE) (YANK3).

HUNK_HUMAN
θ value	5.25075e-16 (rank : 378)	NC score	0.734417 (rank : 93)
Query Neighborhood Hits	2923	Target Neighborhood Hits	884	Shared Neighborhood Hits	800
SwissProt Accessions	P57058	Gene names	HUNK, MAKV
Domain Architecture
Description	Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (Serine/threonine-protein kinase MAK-V) (B19).

KIRR2_HUMAN
θ value	5.25075e-16 (rank : 379)	NC score	0.449615 (rank : 899)
Query Neighborhood Hits	2923	Target Neighborhood Hits	321	Shared Neighborhood Hits	298
SwissProt Accessions	Q6UWL6, Q6P1R1, Q7Z5P1, Q7Z5P2, Q96IQ8, Q9H0T1	Gene names	KIRREL2, NEPH3
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2) (Nephrin-like protein 3).

KPCI_HUMAN
θ value	5.25075e-16 (rank : 380)	NC score	0.709871 (rank : 262)
Query Neighborhood Hits	2923	Target Neighborhood Hits	885	Shared Neighborhood Hits	793
SwissProt Accessions	P41743, Q8WW06	Gene names	PRKCI, DXS1179E
Domain Architecture
Description	Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota) (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) (PRKC-lambda/iota).

ST32C_MOUSE
θ value	5.25075e-16 (rank : 381)	NC score	0.720383 (rank : 183)
Query Neighborhood Hits	2923	Target Neighborhood Hits	824	Shared Neighborhood Hits	779
SwissProt Accessions	Q8QZV4, Q9JJG4	Gene names	Stk32c, Pkek
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 32C (EC 2.7.11.1).

STK24_HUMAN
θ value	5.25075e-16 (rank : 382)	NC score	0.699570 (rank : 320)
Query Neighborhood Hits	2923	Target Neighborhood Hits	853	Shared Neighborhood Hits	791
SwissProt Accessions	Q9Y6E0, O14840	Gene names	STK24, MST3, STK3
Domain Architecture
Description	Serine/threonine-protein kinase 24 (EC 2.7.11.1) (STE20-like kinase MST3) (MST-3) (Mammalian STE20-like protein kinase 3).

CDKL5_HUMAN
θ value	6.85773e-16 (rank : 383)	NC score	0.713280 (rank : 236)
Query Neighborhood Hits	2923	Target Neighborhood Hits	967	Shared Neighborhood Hits	831
SwissProt Accessions	O76039, Q14198, Q5H985, Q9UJL6	Gene names	CDKL5, STK9
Domain Architecture
Description	Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine- protein kinase 9).

CHK1_MOUSE
θ value	6.85773e-16 (rank : 384)	NC score	0.728184 (rank : 142)
Query Neighborhood Hits	2923	Target Neighborhood Hits	839	Shared Neighborhood Hits	780
SwissProt Accessions	O35280, O54925, Q8CI40, Q9D0N2	Gene names	Chek1, Chk1
Domain Architecture
Description	Serine/threonine-protein kinase Chk1 (EC 2.7.11.1).

IKKB_HUMAN
θ value	6.85773e-16 (rank : 385)	NC score	0.718742 (rank : 194)
Query Neighborhood Hits	2923	Target Neighborhood Hits	980	Shared Neighborhood Hits	863
SwissProt Accessions	O14920, O75327	Gene names	IKBKB, IKKB
Domain Architecture
Description	Inhibitor of nuclear factor kappa B kinase subunit beta (EC 2.7.11.10) (I-kappa-B-kinase beta) (IkBKB) (IKK-beta) (IKK-B) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB).

PLK3_MOUSE
θ value	6.85773e-16 (rank : 386)	NC score	0.731093 (rank : 123)
Query Neighborhood Hits	2923	Target Neighborhood Hits	863	Shared Neighborhood Hits	791
SwissProt Accessions	Q60806, Q60822, Q9R009	Gene names	Plk3, Cnk, Fnk
Domain Architecture
Description	Serine/threonine-protein kinase PLK3 (EC 2.7.11.21) (Polo-like kinase 3) (PLK-3) (Cytokine-inducible serine/threonine-protein kinase) (FGF- inducible kinase).

VGFR3_HUMAN
θ value	6.85773e-16 (rank : 387)	NC score	0.648322 (rank : 551)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1037	Shared Neighborhood Hits	968
SwissProt Accessions	P35916	Gene names	FLT4
Domain Architecture
Description	Vascular endothelial growth factor receptor 3 precursor (EC 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4).

IKKB_MOUSE
θ value	8.95645e-16 (rank : 388)	NC score	0.719435 (rank : 187)
Query Neighborhood Hits	2923	Target Neighborhood Hits	984	Shared Neighborhood Hits	864
SwissProt Accessions	O88351, Q9R1J6	Gene names	Ikbkb, Ikkb
Domain Architecture
Description	Inhibitor of nuclear factor kappa B kinase subunit beta (EC 2.7.11.10) (I-kappa-B-kinase beta) (IkBKB) (IKK-beta) (IKK-B) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB).

KGP1A_HUMAN
θ value	8.95645e-16 (rank : 389)	NC score	0.713778 (rank : 230)
Query Neighborhood Hits	2923	Target Neighborhood Hits	901	Shared Neighborhood Hits	798
SwissProt Accessions	Q13976	Gene names	PRKG1, PRKGR1A
Domain Architecture
Description	cGMP-dependent protein kinase 1, alpha isozyme (EC 2.7.11.12) (CGK 1 alpha) (cGKI-alpha).

KGP1B_HUMAN
θ value	8.95645e-16 (rank : 390)	NC score	0.713609 (rank : 232)
Query Neighborhood Hits	2923	Target Neighborhood Hits	921	Shared Neighborhood Hits	815
SwissProt Accessions	P14619	Gene names	PRKG1, PRKG1B, PRKGR1B
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KGP1B_MOUSE
θ value	8.95645e-16 (rank : 391)	NC score	0.713673 (rank : 231)
Query Neighborhood Hits	2923	Target Neighborhood Hits	922	Shared Neighborhood Hits	815
SwissProt Accessions	Q9Z0Z0	Gene names	Prkg1, Prkg1b, Prkgr1b
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

MST4_HUMAN
θ value	8.95645e-16 (rank : 392)	NC score	0.698782 (rank : 326)
Query Neighborhood Hits	2923	Target Neighborhood Hits	852	Shared Neighborhood Hits	788
SwissProt Accessions	Q9P289, Q3ZB77, Q9BXC4	Gene names	MST4, MASK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MST4 (EC 2.7.11.1) (STE20-like kinase MST4) (MST-4) (Mammalian STE20-like protein kinase 4) (Serine/threonine-protein kinase MASK) (Mst3 and SOK1-related kinase).

MST4_MOUSE
θ value	8.95645e-16 (rank : 393)	NC score	0.698824 (rank : 325)
Query Neighborhood Hits	2923	Target Neighborhood Hits	860	Shared Neighborhood Hits	790
SwissProt Accessions	Q99JT2	Gene names	Mst4
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MST4 (EC 2.7.11.1) (STE20-like kinase MST4) (MST-4) (Mammalian STE20-like protein kinase 4).

STK24_MOUSE
θ value	8.95645e-16 (rank : 394)	NC score	0.699099 (rank : 323)
Query Neighborhood Hits	2923	Target Neighborhood Hits	856	Shared Neighborhood Hits	791
SwissProt Accessions	Q99KH8	Gene names	Stk24
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 24 (EC 2.7.11.1).

CHK1_HUMAN
θ value	1.16975e-15 (rank : 395)	NC score	0.727707 (rank : 146)
Query Neighborhood Hits	2923	Target Neighborhood Hits	843	Shared Neighborhood Hits	782
SwissProt Accessions	O14757	Gene names	CHEK1, CHK1
Domain Architecture
Description	Serine/threonine-protein kinase Chk1 (EC 2.7.11.1).

TSSK1_HUMAN
θ value	1.16975e-15 (rank : 396)	NC score	0.728080 (rank : 145)
Query Neighborhood Hits	2923	Target Neighborhood Hits	840	Shared Neighborhood Hits	779
SwissProt Accessions	Q9BXA7	Gene names	TSSK1, SPOGA1, SPOGA4, STK22A, STK22D
Domain Architecture
Description	Testis-specific serine/threonine-protein kinase 1 (EC 2.7.11.1) (TSSK- 1) (Testis-specific kinase 1) (TSK-1) (Serine/threonine-protein kinase 22A).

IGS4B_MOUSE
θ value	1.99529e-15 (rank : 397)	NC score	0.414185 (rank : 931)
Query Neighborhood Hits	2923	Target Neighborhood Hits	328	Shared Neighborhood Hits	305
SwissProt Accessions	Q99N28, Q8BSQ8, Q8K1H8	Gene names	Igsf4b, Necl1, Syncam3, Tsll1
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 4B precursor (Nectin-like protein 1) (Necl-1) (TSLC1-like protein 1) (Synaptic cell adhesion molecule 3).

IKKA_MOUSE
θ value	1.99529e-15 (rank : 398)	NC score	0.720042 (rank : 184)
Query Neighborhood Hits	2923	Target Neighborhood Hits	867	Shared Neighborhood Hits	805
SwissProt Accessions	Q60680, Q80VU2, Q9D2X3	Gene names	Chuk, Ikka
Domain Architecture
Description	Inhibitor of nuclear factor kappa-B kinase alpha subunit (EC 2.7.11.10) (I kappa-B kinase alpha) (IkBKA) (IKK-alpha) (IKK-A) (IkappaB kinase) (I-kappa-B kinase 1) (IKK1) (Conserved helix-loop- helix ubiquitous kinase) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA).

MRCKB_HUMAN
θ value	1.99529e-15 (rank : 399)	NC score	0.634691 (rank : 581)
Query Neighborhood Hits	2923	Target Neighborhood Hits	2239	Shared Neighborhood Hits	1228
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

TSSK4_MOUSE
θ value	1.99529e-15 (rank : 400)	NC score	0.726156 (rank : 157)
Query Neighborhood Hits	2923	Target Neighborhood Hits	840	Shared Neighborhood Hits	779
SwissProt Accessions	Q9D411	Gene names	Tssk4
Domain Architecture	No domain graphic available
Description	Testis-specific serine/threonine-protein kinase 4 (EC 2.7.11.1) (TSSK- 4) (Testis-specific kinase 4) (TSK-4).

YSK4_HUMAN
θ value	1.99529e-15 (rank : 401)	NC score	0.704547 (rank : 290)
Query Neighborhood Hits	2923	Target Neighborhood Hits	921	Shared Neighborhood Hits	819
SwissProt Accessions	Q56UN5, Q56UN1, Q56UN2, Q56UN3, Q56UN4, Q8N4E9, Q9H5T2	Gene names	YSK4, RCK
Domain Architecture	No domain graphic available
Description	SPS1/STE20-related protein kinase YSK4 (EC 2.7.11.1) (Regulated in COPD, protein kinase).

CEAM1_HUMAN
θ value	2.60593e-15 (rank : 402)	NC score	0.384959 (rank : 952)
Query Neighborhood Hits	2923	Target Neighborhood Hits	348	Shared Neighborhood Hits	316
SwissProt Accessions	P13688, O60430, Q13858, Q15600, Q9UQV9	Gene names	CEACAM1, BGP, BGP1
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 1 precursor (Biliary glycoprotein 1) (BGP-1) (CD66 antigen) (CD66a antigen).

CLK4_HUMAN
θ value	2.60593e-15 (rank : 403)	NC score	0.665819 (rank : 510)
Query Neighborhood Hits	2923	Target Neighborhood Hits	759	Shared Neighborhood Hits	733
SwissProt Accessions	Q9HAZ1	Gene names	CLK4
Domain Architecture
Description	Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4).

KKCC2_HUMAN
θ value	2.60593e-15 (rank : 404)	NC score	0.732850 (rank : 110)
Query Neighborhood Hits	2923	Target Neighborhood Hits	852	Shared Neighborhood Hits	782
SwissProt Accessions	Q96RR4, O94883, Q8IUG2, Q8IUG3, Q8N3I4, Q8WY03, Q8WY04, Q8WY05, Q8WY06, Q96RP1, Q96RP2, Q96RR3, Q9BWE9, Q9UER3, Q9UES2, Q9Y5N2	Gene names	CAMKK2, CAMKKB, KIAA0787
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase kinase 2 (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta).

PIM2_HUMAN
θ value	2.60593e-15 (rank : 405)	NC score	0.722307 (rank : 170)
Query Neighborhood Hits	2923	Target Neighborhood Hits	808	Shared Neighborhood Hits	764
SwissProt Accessions	Q9P1W9, Q99739	Gene names	PIM2
Domain Architecture
Description	Serine/threonine-protein kinase Pim-2 (EC 2.7.11.1) (Pim-2h).

STK25_HUMAN
θ value	2.60593e-15 (rank : 406)	NC score	0.696260 (rank : 341)
Query Neighborhood Hits	2923	Target Neighborhood Hits	853	Shared Neighborhood Hits	791
SwissProt Accessions	O00506, Q15522, Q5BJF1	Gene names	STK25, SOK1, YSK1
Domain Architecture
Description	Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Sterile 20/oxidant stress-response kinase 1) (Ste20/oxidant stress response kinase 1) (SOK-1) (Ste20-like kinase).

MOK_MOUSE
θ value	3.40345e-15 (rank : 407)	NC score	0.692418 (rank : 374)
Query Neighborhood Hits	2923	Target Neighborhood Hits	796	Shared Neighborhood Hits	754
SwissProt Accessions	Q9WVS4, Q8CFU4	Gene names	Rage, Mok
Domain Architecture
Description	MAPK/MAK/MRK overlapping kinase (EC 2.7.11.22) (MOK protein kinase).

MRCKB_MOUSE
θ value	3.40345e-15 (rank : 408)	NC score	0.640020 (rank : 571)
Query Neighborhood Hits	2923	Target Neighborhood Hits	2180	Shared Neighborhood Hits	1229
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

ICAM5_HUMAN
θ value	4.44505e-15 (rank : 409)	NC score	0.405152 (rank : 945)
Query Neighborhood Hits	2923	Target Neighborhood Hits	276	Shared Neighborhood Hits	256
SwissProt Accessions	Q9UMF0, Q9Y6F3	Gene names	ICAM5, TLCN, TLN
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

M4K1_MOUSE
θ value	4.44505e-15 (rank : 410)	NC score	0.691741 (rank : 381)
Query Neighborhood Hits	2923	Target Neighborhood Hits	858	Shared Neighborhood Hits	792
SwissProt Accessions	P70218, Q8R3R0, Q99K62	Gene names	Map4k1, Hpk1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1) (Hematopoietic progenitor kinase) (HPK).

MAK_HUMAN
θ value	4.44505e-15 (rank : 411)	NC score	0.700213 (rank : 316)
Query Neighborhood Hits	2923	Target Neighborhood Hits	857	Shared Neighborhood Hits	787
SwissProt Accessions	P20794, Q9NUH7	Gene names	MAK
Domain Architecture
Description	Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male germ cell- associated kinase).

DYRK2_HUMAN
θ value	5.8054e-15 (rank : 412)	NC score	0.683150 (rank : 443)
Query Neighborhood Hits	2923	Target Neighborhood Hits	799	Shared Neighborhood Hits	751
SwissProt Accessions	Q92630	Gene names	DYRK2
Domain Architecture
Description	Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1).

KPCZ_HUMAN
θ value	5.8054e-15 (rank : 413)	NC score	0.706765 (rank : 282)
Query Neighborhood Hits	2923	Target Neighborhood Hits	884	Shared Neighborhood Hits	786
SwissProt Accessions	Q05513, Q15207, Q5SYT5, Q969S4	Gene names	PRKCZ, PKC2
Domain Architecture
Description	Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta).

KPCZ_MOUSE
θ value	5.8054e-15 (rank : 414)	NC score	0.706873 (rank : 281)
Query Neighborhood Hits	2923	Target Neighborhood Hits	882	Shared Neighborhood Hits	787
SwissProt Accessions	Q02956	Gene names	Prkcz, Pkcz
Domain Architecture
Description	Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta).

MAK_MOUSE
θ value	5.8054e-15 (rank : 415)	NC score	0.701121 (rank : 312)
Query Neighborhood Hits	2923	Target Neighborhood Hits	873	Shared Neighborhood Hits	796
SwissProt Accessions	Q04859	Gene names	Mak, Rck
Domain Architecture
Description	Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male germ cell- associated kinase) (Protein kinase RCK).

ST32B_HUMAN
θ value	5.8054e-15 (rank : 416)	NC score	0.717938 (rank : 201)
Query Neighborhood Hits	2923	Target Neighborhood Hits	830	Shared Neighborhood Hits	779
SwissProt Accessions	Q9NY57, Q6UXH3, Q8IY14	Gene names	STK32B
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 32B (EC 2.7.11.1) (YANK2).

TNIK_HUMAN
θ value	5.8054e-15 (rank : 417)	NC score	0.684820 (rank : 429)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1570	Shared Neighborhood Hits	1095
SwissProt Accessions	Q9UKE5, O60298, Q8WUY7, Q9UKD8, Q9UKD9, Q9UKE0, Q9UKE1, Q9UKE2, Q9UKE3, Q9UKE4	Gene names	TNIK, KIAA0551
Domain Architecture
Description	TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1).

CLK4_MOUSE
θ value	7.58209e-15 (rank : 418)	NC score	0.664668 (rank : 514)
Query Neighborhood Hits	2923	Target Neighborhood Hits	759	Shared Neighborhood Hits	734
SwissProt Accessions	O35493, O35721, Q8CEU9, Q99LU6	Gene names	Clk4
Domain Architecture
Description	Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4).

FGFR1_MOUSE
θ value	7.58209e-15 (rank : 419)	NC score	0.693521 (rank : 361)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1068	Shared Neighborhood Hits	1004
SwissProt Accessions	P16092, Q01736, Q61562, Q80T10	Gene names	Fgfr1, Flg
Domain Architecture
Description	Basic fibroblast growth factor receptor 1 precursor (EC 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) (CD331 antigen).

KKCC2_MOUSE
θ value	7.58209e-15 (rank : 420)	NC score	0.732813 (rank : 111)
Query Neighborhood Hits	2923	Target Neighborhood Hits	855	Shared Neighborhood Hits	784
SwissProt Accessions	Q8C078, Q80TS0, Q8BXM8, Q8C0G3, Q8CH42, Q8QZT7	Gene names	Camkk2, Kiaa0787
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase kinase 2 (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta).

ULK4_MOUSE
θ value	7.58209e-15 (rank : 421)	NC score	0.721380 (rank : 176)
Query Neighborhood Hits	2923	Target Neighborhood Hits	793	Shared Neighborhood Hits	752
SwissProt Accessions	Q3V129, Q2VP87, Q32LZ6, Q8BLS0, Q8C8Z5, Q9D4H6	Gene names	Ulk4
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK4 (EC 2.7.11.1) (Unc-51-like kinase 4).

CDK3_HUMAN
θ value	9.90251e-15 (rank : 422)	NC score	0.700290 (rank : 315)
Query Neighborhood Hits	2923	Target Neighborhood Hits	843	Shared Neighborhood Hits	787
SwissProt Accessions	Q00526	Gene names	CDK3
Domain Architecture
Description	Cell division protein kinase 3 (EC 2.7.11.22).

DYR1B_MOUSE
θ value	9.90251e-15 (rank : 423)	NC score	0.681592 (rank : 453)
Query Neighborhood Hits	2923	Target Neighborhood Hits	799	Shared Neighborhood Hits	763
SwissProt Accessions	Q9Z188	Gene names	Dyrk1b
Domain Architecture
Description	Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1).

IKKA_HUMAN
θ value	9.90251e-15 (rank : 424)	NC score	0.718122 (rank : 199)
Query Neighborhood Hits	2923	Target Neighborhood Hits	863	Shared Neighborhood Hits	798
SwissProt Accessions	O15111, O14666, Q13132, Q92467	Gene names	CHUK, IKKA
Domain Architecture
Description	Inhibitor of nuclear factor kappa-B kinase alpha subunit (EC 2.7.11.10) (I kappa-B kinase alpha) (IkBKA) (IKK-alpha) (IKK-A) (IkappaB kinase) (I-kappa-B kinase 1) (IKK1) (Conserved helix-loop- helix ubiquitous kinase) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA).

VGFR3_MOUSE
θ value	9.90251e-15 (rank : 425)	NC score	0.651977 (rank : 545)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1056	Shared Neighborhood Hits	990
SwissProt Accessions	P35917	Gene names	Flt4, Flt-4
Domain Architecture
Description	Vascular endothelial growth factor receptor 3 precursor (EC 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4).

MAST4_HUMAN
θ value	1.29331e-14 (rank : 426)	NC score	0.705786 (rank : 286)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1804	Shared Neighborhood Hits	1098
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

NEGR1_HUMAN
θ value	1.29331e-14 (rank : 427)	NC score	0.484361 (rank : 864)
Query Neighborhood Hits	2923	Target Neighborhood Hits	346	Shared Neighborhood Hits	337
SwissProt Accessions	Q7Z3B1, Q5VT21, Q6UY06, Q8NAQ3	Gene names	NEGR1
Domain Architecture	No domain graphic available
Description	Neuronal growth regulator 1 precursor.

PCTK1_HUMAN
θ value	1.29331e-14 (rank : 428)	NC score	0.692421 (rank : 373)
Query Neighborhood Hits	2923	Target Neighborhood Hits	832	Shared Neighborhood Hits	777
SwissProt Accessions	Q00536	Gene names	PCTK1
Domain Architecture
Description	Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22) (PCTAIRE- motif protein kinase 1).

PCTK3_HUMAN
θ value	1.29331e-14 (rank : 429)	NC score	0.690284 (rank : 397)
Query Neighborhood Hits	2923	Target Neighborhood Hits	827	Shared Neighborhood Hits	769
SwissProt Accessions	Q07002, Q5VXQ2, Q96F90	Gene names	PCTK3
Domain Architecture
Description	Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22) (PCTAIRE- motif protein kinase 3).

PIM2_MOUSE
θ value	1.29331e-14 (rank : 430)	NC score	0.721401 (rank : 175)
Query Neighborhood Hits	2923	Target Neighborhood Hits	809	Shared Neighborhood Hits	763
SwissProt Accessions	Q62070, Q62071, Q62072	Gene names	Pim2, Pim-2
Domain Architecture
Description	Serine/threonine-protein kinase Pim-2 (EC 2.7.11.1).

STK25_MOUSE
θ value	1.29331e-14 (rank : 431)	NC score	0.695840 (rank : 345)
Query Neighborhood Hits	2923	Target Neighborhood Hits	851	Shared Neighborhood Hits	790
SwissProt Accessions	Q9Z2W1	Gene names	Stk25, Sok1
Domain Architecture
Description	Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Sterile 20/oxidant stress-response kinase 1) (Ste20/oxidant stress response kinase 1) (SOK-1) (Ste20-like kinase).

TSSK2_MOUSE
θ value	1.29331e-14 (rank : 432)	NC score	0.726653 (rank : 151)
Query Neighborhood Hits	2923	Target Neighborhood Hits	819	Shared Neighborhood Hits	765
SwissProt Accessions	O54863	Gene names	Tssk2, Stk22b
Domain Architecture
Description	Testis-specific serine/threonine-protein kinase 2 (EC 2.7.11.1) (TSSK- 2) (Testis-specific kinase 2) (TSK-2) (Serine/threonine-protein kinase 22B).

MAST2_MOUSE
θ value	1.68911e-14 (rank : 433)	NC score	0.708850 (rank : 270)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1110	Shared Neighborhood Hits	865
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MK03_HUMAN
θ value	1.68911e-14 (rank : 434)	NC score	0.685535 (rank : 424)
Query Neighborhood Hits	2923	Target Neighborhood Hits	837	Shared Neighborhood Hits	778
SwissProt Accessions	P27361	Gene names	MAPK3, ERK1, PRKM3
Domain Architecture
Description	Mitogen-activated protein kinase 3 (EC 2.7.11.24) (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase 1) (MAPK 1) (p44-ERK1) (ERT2) (p44-MAPK) (Microtubule- associated protein 2 kinase).

MK03_MOUSE
θ value	1.68911e-14 (rank : 435)	NC score	0.685749 (rank : 422)
Query Neighborhood Hits	2923	Target Neighborhood Hits	840	Shared Neighborhood Hits	780
SwissProt Accessions	Q63844, Q61531, Q8K0X5, Q91YW5	Gene names	Mapk3, Erk1, Prkm3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 3 (EC 2.7.11.24) (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase 1) (MAPK 1) (p44-ERK1) (ERT2) (p44-MAPK) (Microtubule- associated protein 2 kinase) (MNK1).

MRCKG_MOUSE
θ value	1.68911e-14 (rank : 436)	NC score	0.678285 (rank : 464)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1466	Shared Neighborhood Hits	1038
SwissProt Accessions	Q80UW5	Gene names	Cdc42bpg
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

DYR1B_HUMAN
θ value	2.20605e-14 (rank : 437)	NC score	0.677678 (rank : 467)
Query Neighborhood Hits	2923	Target Neighborhood Hits	831	Shared Neighborhood Hits	774
SwissProt Accessions	Q9Y463, O75258, O75788, O75789	Gene names	DYRK1B, MIRK
Domain Architecture
Description	Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1) (Mirk protein kinase) (Minibrain-related kinase).

NEK9_MOUSE
θ value	2.20605e-14 (rank : 438)	NC score	0.698423 (rank : 331)
Query Neighborhood Hits	2923	Target Neighborhood Hits	890	Shared Neighborhood Hits	798
SwissProt Accessions	Q8K1R7, Q8R3P1	Gene names	Nek9, Nercc
Domain Architecture
Description	Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (NimA-related protein kinase 9) (Never in mitosis A-related kinase 9).

TSSK4_HUMAN
θ value	2.20605e-14 (rank : 439)	NC score	0.724194 (rank : 163)
Query Neighborhood Hits	2923	Target Neighborhood Hits	836	Shared Neighborhood Hits	783
SwissProt Accessions	Q6SA08	Gene names	TSSK4, C14orf20, STK22E
Domain Architecture	No domain graphic available
Description	Testis-specific serine/threonine-protein kinase 4 (EC 2.7.11.1) (TSSK- 4) (Testis-specific kinase 4) (TSK-4) (Serine/threonine-protein kinase 22E).

MRCKA_HUMAN
θ value	2.88119e-14 (rank : 440)	NC score	0.648233 (rank : 552)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1999	Shared Neighborhood Hits	1174
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

PCTK1_MOUSE
θ value	2.88119e-14 (rank : 441)	NC score	0.691964 (rank : 375)
Query Neighborhood Hits	2923	Target Neighborhood Hits	832	Shared Neighborhood Hits	776
SwissProt Accessions	Q04735	Gene names	Pctk1, Crk5
Domain Architecture
Description	Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22) (PCTAIRE- motif protein kinase 1) (CRK5).

RK_HUMAN
θ value	2.88119e-14 (rank : 442)	NC score	0.711115 (rank : 245)
Query Neighborhood Hits	2923	Target Neighborhood Hits	835	Shared Neighborhood Hits	777
SwissProt Accessions	Q15835	Gene names	GRK1, RHOK
Domain Architecture
Description	Rhodopsin kinase precursor (EC 2.7.11.14) (RK) (G protein-coupled receptor kinase 1).

SBK1_MOUSE
θ value	2.88119e-14 (rank : 443)	NC score	0.731997 (rank : 118)
Query Neighborhood Hits	2923	Target Neighborhood Hits	824	Shared Neighborhood Hits	774
SwissProt Accessions	Q8QZX0	Gene names	Sbk1, Sbk
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SBK1 (EC 2.7.11.1) (SH3-binding kinase 1).

SLK_MOUSE
θ value	2.88119e-14 (rank : 444)	NC score	0.697627 (rank : 335)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1798	Shared Neighborhood Hits	1173
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

ST38L_HUMAN
θ value	2.88119e-14 (rank : 445)	NC score	0.704700 (rank : 289)
Query Neighborhood Hits	2923	Target Neighborhood Hits	824	Shared Neighborhood Hits	777
SwissProt Accessions	Q9Y2H1, Q8TBX7	Gene names	STK38L, KIAA0965, NDR2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 38-like (EC 2.7.11.1) (NDR2 protein kinase) (Nuclear Dbf2-related kinase 2).

COCA1_MOUSE
θ value	3.76295e-14 (rank : 446)	NC score	0.242195 (rank : 1036)
Query Neighborhood Hits	2923	Target Neighborhood Hits	467	Shared Neighborhood Hits	259
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

M3K5_HUMAN
θ value	3.76295e-14 (rank : 447)	NC score	0.708131 (rank : 279)
Query Neighborhood Hits	2923	Target Neighborhood Hits	868	Shared Neighborhood Hits	793
SwissProt Accessions	Q99683, Q5THN3, Q99461	Gene names	MAP3K5, ASK1, MAPKKK5, MEKK5
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5) (Apoptosis signal- regulating kinase 1) (ASK-1).

M3K3_HUMAN
θ value	4.91457e-14 (rank : 448)	NC score	0.709983 (rank : 261)
Query Neighborhood Hits	2923	Target Neighborhood Hits	885	Shared Neighborhood Hits	808
SwissProt Accessions	Q99759	Gene names	MAP3K3, MAPKKK3, MEKK3
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3).

M3K3_MOUSE
θ value	4.91457e-14 (rank : 449)	NC score	0.710362 (rank : 256)
Query Neighborhood Hits	2923	Target Neighborhood Hits	876	Shared Neighborhood Hits	799
SwissProt Accessions	Q61084	Gene names	Map3k3, Mekk3
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3).

M3K5_MOUSE
θ value	4.91457e-14 (rank : 450)	NC score	0.708149 (rank : 278)
Query Neighborhood Hits	2923	Target Neighborhood Hits	867	Shared Neighborhood Hits	793
SwissProt Accessions	O35099	Gene names	Map3k5, Ask1, Mekk5
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5) (Apoptosis signal- regulating kinase 1) (ASK-1).

MK12_MOUSE
θ value	4.91457e-14 (rank : 451)	NC score	0.693868 (rank : 356)
Query Neighborhood Hits	2923	Target Neighborhood Hits	835	Shared Neighborhood Hits	778
SwissProt Accessions	O08911, Q9D0M4	Gene names	Mapk12, Sapk3
Domain Architecture
Description	Mitogen-activated protein kinase 12 (EC 2.7.11.24) (Extracellular signal-regulated kinase 6) (ERK-6) (Stress-activated protein kinase 3) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma).

MK14_MOUSE
θ value	4.91457e-14 (rank : 452)	NC score	0.691036 (rank : 387)
Query Neighborhood Hits	2923	Target Neighborhood Hits	838	Shared Neighborhood Hits	780
SwissProt Accessions	P47811, O08666, Q3UZS3, Q8C289, Q9JLV8, Q9QZ80	Gene names	Mapk14, Crk1, Csbp1, Csbp2
Domain Architecture
Description	Mitogen-activated protein kinase 14 (EC 2.7.11.24) (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (CRK1).

MRCKG_HUMAN
θ value	4.91457e-14 (rank : 453)	NC score	0.678168 (rank : 465)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1519	Shared Neighborhood Hits	1038
SwissProt Accessions	Q6DT37, O00565	Gene names	CDC42BPG
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

CDK2_HUMAN
θ value	6.41864e-14 (rank : 454)	NC score	0.696975 (rank : 337)
Query Neighborhood Hits	2923	Target Neighborhood Hits	832	Shared Neighborhood Hits	780
SwissProt Accessions	P24941	Gene names	CDK2
Domain Architecture
Description	Cell division protein kinase 2 (EC 2.7.11.22) (p33 protein kinase).

ICAM5_MOUSE
θ value	6.41864e-14 (rank : 455)	NC score	0.418010 (rank : 922)
Query Neighborhood Hits	2923	Target Neighborhood Hits	308	Shared Neighborhood Hits	274
SwissProt Accessions	Q60625	Gene names	Icam5, Tlcn
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

MAST3_HUMAN
θ value	6.41864e-14 (rank : 456)	NC score	0.710842 (rank : 248)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1128	Shared Neighborhood Hits	890
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

MK01_HUMAN
θ value	6.41864e-14 (rank : 457)	NC score	0.684990 (rank : 427)
Query Neighborhood Hits	2923	Target Neighborhood Hits	836	Shared Neighborhood Hits	779
SwissProt Accessions	P28482	Gene names	MAPK1, ERK2, PRKM1
Domain Architecture
Description	Mitogen-activated protein kinase 1 (EC 2.7.11.24) (Extracellular signal-regulated kinase 2) (ERK-2) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2) (p42-MAPK) (ERT1).

MK01_MOUSE
θ value	6.41864e-14 (rank : 458)	NC score	0.684823 (rank : 428)
Query Neighborhood Hits	2923	Target Neighborhood Hits	836	Shared Neighborhood Hits	779
SwissProt Accessions	P63085, P27703, Q3V1U6	Gene names	Mapk1, Erk2, Mapk, Prkm1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 1 (EC 2.7.11.24) (Extracellular signal-regulated kinase 2) (ERK-2) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2) (p42-MAPK) (ERT1).

NEK6_HUMAN
θ value	6.41864e-14 (rank : 459)	NC score	0.714784 (rank : 224)
Query Neighborhood Hits	2923	Target Neighborhood Hits	848	Shared Neighborhood Hits	791
SwissProt Accessions	Q9HC98, Q96E83, Q9ULX2	Gene names	NEK6
Domain Architecture
Description	Serine/threonine-protein kinase Nek6 (EC 2.7.11.1) (NimA-related protein kinase 6) (Protein kinase SID6-1512).

SBK1_HUMAN
θ value	6.41864e-14 (rank : 460)	NC score	0.731394 (rank : 121)
Query Neighborhood Hits	2923	Target Neighborhood Hits	828	Shared Neighborhood Hits	777
SwissProt Accessions	Q52WX2	Gene names	SBK1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SBK1 (EC 2.7.11.1) (SH3-binding kinase 1).

ST32A_MOUSE
θ value	6.41864e-14 (rank : 461)	NC score	0.719958 (rank : 185)
Query Neighborhood Hits	2923	Target Neighborhood Hits	833	Shared Neighborhood Hits	784
SwissProt Accessions	Q8BGW6, Q7TPQ4	Gene names	Stk32a
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 32A (EC 2.7.11.1).

TTK_MOUSE
θ value	6.41864e-14 (rank : 462)	NC score	0.710833 (rank : 250)
Query Neighborhood Hits	2923	Target Neighborhood Hits	803	Shared Neighborhood Hits	735
SwissProt Accessions	P35761	Gene names	Ttk, Esk
Domain Architecture
Description	Dual specificity protein kinase TTK (EC 2.7.12.1) (ESK) (PYT).

DYR1A_HUMAN
θ value	8.38298e-14 (rank : 463)	NC score	0.669625 (rank : 495)
Query Neighborhood Hits	2923	Target Neighborhood Hits	764	Shared Neighborhood Hits	740
SwissProt Accessions	Q13627, O60769, Q92582, Q92810, Q9UNM5	Gene names	DYRK1A, DYRK, MNB, MNBH
Domain Architecture
Description	Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.1) (Protein kinase minibrain homolog) (MNBH) (HP86) (Dual specificity YAK1-related kinase).

DYR1A_MOUSE
θ value	8.38298e-14 (rank : 464)	NC score	0.669628 (rank : 494)
Query Neighborhood Hits	2923	Target Neighborhood Hits	762	Shared Neighborhood Hits	739
SwissProt Accessions	Q61214	Gene names	Dyrk1a, Dyrk
Domain Architecture
Description	Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.1) (Protein kinase minibrain homolog) (MNBH) (MP86) (Dual specificity YAK1-related kinase).

FGFR1_HUMAN
θ value	8.38298e-14 (rank : 465)	NC score	0.693759 (rank : 358)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1069	Shared Neighborhood Hits	1005
SwissProt Accessions	P11362, P17049, Q02063, Q02065, Q14306, Q14307, Q8N685	Gene names	FGFR1, FGFBR, FLG, FLT2
Domain Architecture
Description	Basic fibroblast growth factor receptor 1 precursor (EC 2.7.10.1) (FGFR-1) (bFGF-R) (Fms-like tyrosine kinase 2) (c-fgr) (CD331 antigen).

MAST2_HUMAN
θ value	8.38298e-14 (rank : 466)	NC score	0.707539 (rank : 280)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1189	Shared Neighborhood Hits	898
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

NEK6_MOUSE
θ value	8.38298e-14 (rank : 467)	NC score	0.714710 (rank : 225)
Query Neighborhood Hits	2923	Target Neighborhood Hits	851	Shared Neighborhood Hits	791
SwissProt Accessions	Q9ES70, Q3TCE9, Q8C6E6, Q9D0E2, Q9DBI8	Gene names	Nek6
Domain Architecture
Description	Serine/threonine-protein kinase Nek6 (EC 2.7.11.1) (NimA-related protein kinase 6).

PCTK2_HUMAN
θ value	8.38298e-14 (rank : 468)	NC score	0.689894 (rank : 399)
Query Neighborhood Hits	2923	Target Neighborhood Hits	837	Shared Neighborhood Hits	777
SwissProt Accessions	Q00537, Q8NEB8	Gene names	PCTK2
Domain Architecture
Description	Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22) (PCTAIRE- motif protein kinase 2).

PCTK2_MOUSE
θ value	8.38298e-14 (rank : 469)	NC score	0.689529 (rank : 405)
Query Neighborhood Hits	2923	Target Neighborhood Hits	836	Shared Neighborhood Hits	776
SwissProt Accessions	Q8K0D0	Gene names	Pctk2
Domain Architecture
Description	Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22) (PCTAIRE- motif protein kinase 2).

PIM1_HUMAN
θ value	8.38298e-14 (rank : 470)	NC score	0.718402 (rank : 197)
Query Neighborhood Hits	2923	Target Neighborhood Hits	797	Shared Neighborhood Hits	758
SwissProt Accessions	P11309, Q38RT9, Q96RG3	Gene names	PIM1
Domain Architecture
Description	Proto-oncogene serine/threonine-protein kinase Pim-1 (EC 2.7.11.1).

CDK2_MOUSE
θ value	1.09485e-13 (rank : 471)	NC score	0.693166 (rank : 366)
Query Neighborhood Hits	2923	Target Neighborhood Hits	828	Shared Neighborhood Hits	776
SwissProt Accessions	P97377, O55105	Gene names	Cdk2
Domain Architecture
Description	Cell division protein kinase 2 (EC 2.7.11.22).

CEAM6_HUMAN
θ value	1.09485e-13 (rank : 472)	NC score	0.346722 (rank : 979)
Query Neighborhood Hits	2923	Target Neighborhood Hits	308	Shared Neighborhood Hits	291
SwissProt Accessions	P40199, Q14920	Gene names	CEACAM6, NCA
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 6 precursor (Normal cross-reacting antigen) (Nonspecific crossreacting antigen) (CD66c antigen).

M3K15_HUMAN
θ value	1.09485e-13 (rank : 473)	NC score	0.706748 (rank : 283)
Query Neighborhood Hits	2923	Target Neighborhood Hits	914	Shared Neighborhood Hits	815
SwissProt Accessions	Q6ZN16, Q5JPR4, Q6ZMV3	Gene names	MAP3K15
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 15 (EC 2.7.11.25) (MAPK/ERK kinase kinase 15) (MEK kinase 15) (MEKK 15).

M4K1_HUMAN
θ value	1.09485e-13 (rank : 474)	NC score	0.692949 (rank : 369)
Query Neighborhood Hits	2923	Target Neighborhood Hits	884	Shared Neighborhood Hits	800
SwissProt Accessions	Q92918	Gene names	MAP4K1, HPK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1) (Hematopoietic progenitor kinase).

M4K2_HUMAN
θ value	1.09485e-13 (rank : 475)	NC score	0.691190 (rank : 386)
Query Neighborhood Hits	2923	Target Neighborhood Hits	850	Shared Neighborhood Hits	784
SwissProt Accessions	Q12851	Gene names	MAP4K2, GCK, RAB8IP
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Germinal center kinase) (GC kinase) (Rab8-interacting protein) (B lymphocyte serine/threonine-protein kinase).

MK14_HUMAN
θ value	1.09485e-13 (rank : 476)	NC score	0.690913 (rank : 389)
Query Neighborhood Hits	2923	Target Neighborhood Hits	838	Shared Neighborhood Hits	780
SwissProt Accessions	Q16539, O60776, Q13083, Q14084, Q8TDX0	Gene names	MAPK14, CSBP, CSBP1, CSBP2, MXI2
Domain Architecture
Description	Mitogen-activated protein kinase 14 (EC 2.7.11.24) (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Cytokine suppressive anti-inflammatory drug-binding protein) (CSAID-binding protein) (CSBP) (MAX-interacting protein 2) (MAP kinase MXI2) (SAPK2A).

NEK7_HUMAN
θ value	1.09485e-13 (rank : 477)	NC score	0.710855 (rank : 247)
Query Neighborhood Hits	2923	Target Neighborhood Hits	846	Shared Neighborhood Hits	790
SwissProt Accessions	Q8TDX7	Gene names	NEK7
Domain Architecture
Description	Serine/threonine-protein kinase Nek7 (EC 2.7.11.1) (NimA-related protein kinase 7).

NEK2_HUMAN
θ value	1.42992e-13 (rank : 478)	NC score	0.718835 (rank : 192)
Query Neighborhood Hits	2923	Target Neighborhood Hits	908	Shared Neighborhood Hits	818
SwissProt Accessions	P51955, Q53FD6, Q5VXZ1, Q6NZX8, Q7Z634, Q86XH2, Q96QN9	Gene names	NEK2, NLK1
Domain Architecture
Description	Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (NimA-related protein kinase 2) (NimA-like protein kinase 1) (HSPK 21).

ST32A_HUMAN
θ value	1.42992e-13 (rank : 479)	NC score	0.718914 (rank : 191)
Query Neighborhood Hits	2923	Target Neighborhood Hits	834	Shared Neighborhood Hits	780
SwissProt Accessions	Q8WU08	Gene names	STK32A
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 32A (EC 2.7.11.1) (YANK1).

DMPK_HUMAN
θ value	1.86753e-13 (rank : 480)	NC score	0.695935 (rank : 344)
Query Neighborhood Hits	2923	Target Neighborhood Hits	944	Shared Neighborhood Hits	830
SwissProt Accessions	Q09013, Q16205	Gene names	DMPK, MDPK
Domain Architecture
Description	Myotonin-protein kinase (EC 2.7.11.1) (Myotonic dystrophy protein kinase) (MDPK) (DM-kinase) (DMK) (DMPK) (MT-PK).

MINK1_HUMAN
θ value	1.86753e-13 (rank : 481)	NC score	0.683314 (rank : 442)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1477	Shared Neighborhood Hits	1083
SwissProt Accessions	Q8N4C8, Q9P1X1, Q9P2R8	Gene names	MINK1, MAP4K6, MINK
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

NEGR1_MOUSE
θ value	1.86753e-13 (rank : 482)	NC score	0.481736 (rank : 868)
Query Neighborhood Hits	2923	Target Neighborhood Hits	349	Shared Neighborhood Hits	337
SwissProt Accessions	Q80Z24, Q3UHQ8, Q80T70	Gene names	Negr1, Kiaa3001, Ntra
Domain Architecture	No domain graphic available
Description	Neuronal growth regulator 1 precursor (Kilon protein) (Kindred of IgLON) (Neurotractin).

NEK7_MOUSE
θ value	1.86753e-13 (rank : 483)	NC score	0.710900 (rank : 246)
Query Neighborhood Hits	2923	Target Neighborhood Hits	847	Shared Neighborhood Hits	791
SwissProt Accessions	Q9ES74, Q3UEV7	Gene names	Nek7
Domain Architecture
Description	Serine/threonine-protein kinase Nek7 (EC 2.7.11.1) (NimA-related protein kinase 7).

NPTN_MOUSE
θ value	1.86753e-13 (rank : 484)	NC score	0.412025 (rank : 935)
Query Neighborhood Hits	2923	Target Neighborhood Hits	216	Shared Neighborhood Hits	212
SwissProt Accessions	P97300, Q3U519, Q8C637, Q8C6H8	Gene names	Nptn, Sdfr1, Sdr1
Domain Architecture	No domain graphic available
Description	Neuroplastin precursor (Stromal cell-derived receptor 1) (SDR-1).

SLK_HUMAN
θ value	1.86753e-13 (rank : 485)	NC score	0.696280 (rank : 340)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1775	Shared Neighborhood Hits	1156
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

STK38_HUMAN
θ value	1.86753e-13 (rank : 486)	NC score	0.704028 (rank : 293)
Query Neighborhood Hits	2923	Target Neighborhood Hits	840	Shared Neighborhood Hits	784
SwissProt Accessions	Q15208	Gene names	STK38, NDR1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1 protein kinase) (Nuclear Dbf2-related kinase 1).

FCRL2_HUMAN
θ value	2.43908e-13 (rank : 487)	NC score	0.387469 (rank : 949)
Query Neighborhood Hits	2923	Target Neighborhood Hits	251	Shared Neighborhood Hits	231
SwissProt Accessions	Q96LA5, Q6NTA1, Q9BZI4, Q9BZI5, Q9BZI6	Gene names	FCRL2, FCRH2, IFGP4, IRTA4, SPAP1
Domain Architecture	No domain graphic available
Description	Fc receptor-like protein 2 precursor (SH2 domain-containing phosphatase anchor protein 1) (Fc receptor homolog 2) (FcRH2) (Immunoglobulin receptor translocation-associated 4 protein).

KGP2_HUMAN
θ value	2.43908e-13 (rank : 488)	NC score	0.715962 (rank : 211)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1023	Shared Neighborhood Hits	871
SwissProt Accessions	Q13237, O00125, O60916	Gene names	PRKG2, PRKGR2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

M4K3_HUMAN
θ value	2.43908e-13 (rank : 489)	NC score	0.692805 (rank : 371)
Query Neighborhood Hits	2923	Target Neighborhood Hits	857	Shared Neighborhood Hits	789
SwissProt Accessions	Q8IVH8, Q8IVH7, Q9UDM5, Q9Y6R5	Gene names	MAP4K3
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3) (Germinal center kinase-related protein kinase) (GLK).

MAP4_HUMAN
θ value	2.43908e-13 (rank : 490)	NC score	0.097127 (rank : 1212)
Query Neighborhood Hits	2923	Target Neighborhood Hits	428	Shared Neighborhood Hits	221
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

FGFR3_MOUSE
θ value	3.18553e-13 (rank : 491)	NC score	0.686343 (rank : 421)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1059	Shared Neighborhood Hits	994
SwissProt Accessions	Q61851, Q61564, Q63834	Gene names	Fgfr3, Mfr3, Sam3
Domain Architecture
Description	Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1) (FGFR-3) (Heparin-binding growth factor receptor) (CD333 antigen).

M4K2_MOUSE
θ value	3.18553e-13 (rank : 492)	NC score	0.691271 (rank : 384)
Query Neighborhood Hits	2923	Target Neighborhood Hits	843	Shared Neighborhood Hits	777
SwissProt Accessions	Q61161	Gene names	Map4k2, Rab8ip
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Germinal center kinase) (GCK) (Rab8-interacting protein).

MINK1_MOUSE
θ value	3.18553e-13 (rank : 493)	NC score	0.682859 (rank : 444)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1451	Shared Neighborhood Hits	1066
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

M3K8_HUMAN
θ value	4.16044e-13 (rank : 494)	NC score	0.704865 (rank : 288)
Query Neighborhood Hits	2923	Target Neighborhood Hits	807	Shared Neighborhood Hits	769
SwissProt Accessions	P41279, Q14275, Q9HC81	Gene names	MAP3K8, COT
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 8 (EC 2.7.11.25) (COT proto-oncogene serine/threonine-protein kinase) (C-COT) (Cancer Osaka thyroid oncogene).

SON_HUMAN
θ value	4.16044e-13 (rank : 495)	NC score	0.090350 (rank : 1232)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1568	Shared Neighborhood Hits	531
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

CLK1_HUMAN
θ value	5.43371e-13 (rank : 496)	NC score	0.667399 (rank : 504)
Query Neighborhood Hits	2923	Target Neighborhood Hits	756	Shared Neighborhood Hits	733
SwissProt Accessions	P49759	Gene names	CLK1, CLK
Domain Architecture
Description	Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1).

ICK_MOUSE
θ value	5.43371e-13 (rank : 497)	NC score	0.700734 (rank : 314)
Query Neighborhood Hits	2923	Target Neighborhood Hits	860	Shared Neighborhood Hits	795
SwissProt Accessions	Q9JKV2, Q8K138	Gene names	Ick
Domain Architecture
Description	Serine/threonine-protein kinase ICK (EC 2.7.11.22) (Intestinal cell kinase) (mICK) (MAK-related kinase) (MRK).

KGP2_MOUSE
θ value	5.43371e-13 (rank : 498)	NC score	0.715972 (rank : 210)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1029	Shared Neighborhood Hits	883
SwissProt Accessions	Q61410	Gene names	Prkg2, Prkgr2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

M3K2_HUMAN
θ value	7.09661e-13 (rank : 499)	NC score	0.708168 (rank : 277)
Query Neighborhood Hits	2923	Target Neighborhood Hits	849	Shared Neighborhood Hits	787
SwissProt Accessions	Q9Y2U5, Q53QL9, Q53S75, Q59GZ6, Q8NC32, Q9NYK3	Gene names	MAP3K2, MAPKKK2, MEKK2
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2).

MK13_HUMAN
θ value	7.09661e-13 (rank : 500)	NC score	0.689596 (rank : 404)
Query Neighborhood Hits	2923	Target Neighborhood Hits	829	Shared Neighborhood Hits	776
SwissProt Accessions	O15264, O14739, O15124, Q9UNU0	Gene names	MAPK13, PRKM13, SAPK4
Domain Architecture
Description	Mitogen-activated protein kinase 13 (EC 2.7.11.24) (Stress-activated protein kinase 4) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta).

TTK_HUMAN
θ value	7.09661e-13 (rank : 501)	NC score	0.711888 (rank : 242)
Query Neighborhood Hits	2923	Target Neighborhood Hits	816	Shared Neighborhood Hits	749
SwissProt Accessions	P33981	Gene names	TTK, MPS1L1
Domain Architecture
Description	Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein kinase) (PYT).

ATL3_HUMAN
θ value	9.26847e-13 (rank : 502)	NC score	0.283502 (rank : 1013)
Query Neighborhood Hits	2923	Target Neighborhood Hits	414	Shared Neighborhood Hits	290
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

EPHA1_HUMAN
θ value	9.26847e-13 (rank : 503)	NC score	0.569889 (rank : 710)
Query Neighborhood Hits	2923	Target Neighborhood Hits	997	Shared Neighborhood Hits	828
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

FER_HUMAN
θ value	9.26847e-13 (rank : 504)	NC score	0.602957 (rank : 629)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1278	Shared Neighborhood Hits	963
SwissProt Accessions	P16591	Gene names	FER, TYK3
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2) (p94-FER) (c- FER).

FSTL4_HUMAN
θ value	9.26847e-13 (rank : 505)	NC score	0.423125 (rank : 917)
Query Neighborhood Hits	2923	Target Neighborhood Hits	344	Shared Neighborhood Hits	275
SwissProt Accessions	Q6MZW2, Q8TBU0, Q9UPU1	Gene names	FSTL4, KIAA1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4).

CLK2_HUMAN
θ value	1.2105e-12 (rank : 506)	NC score	0.661283 (rank : 523)
Query Neighborhood Hits	2923	Target Neighborhood Hits	752	Shared Neighborhood Hits	734
SwissProt Accessions	P49760, Q96CQ0	Gene names	CLK2
Domain Architecture
Description	Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2).

IGS4B_HUMAN
θ value	1.2105e-12 (rank : 507)	NC score	0.405291 (rank : 944)
Query Neighborhood Hits	2923	Target Neighborhood Hits	305	Shared Neighborhood Hits	288
SwissProt Accessions	Q8N126, Q9NVJ5, Q9UJP1	Gene names	IGSF4B, NECL1, SYNCAM3, TSLL1
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 4B precursor (Nectin-like protein 1) (TSLC1-like protein 1) (Synaptic cell adhesion molecule 3) (Brain immunoglobulin receptor).

PFTK1_HUMAN
θ value	1.2105e-12 (rank : 508)	NC score	0.693065 (rank : 367)
Query Neighborhood Hits	2923	Target Neighborhood Hits	834	Shared Neighborhood Hits	778
SwissProt Accessions	O94921, Q75N06, Q75N22, Q8N764, Q9H3D7, Q9UDR0	Gene names	PFTK1, KIAA0834
Domain Architecture
Description	Serine/threonine-protein kinase PFTAIRE-1 (EC 2.7.11.22).

PIM1_MOUSE
θ value	1.2105e-12 (rank : 509)	NC score	0.716860 (rank : 205)
Query Neighborhood Hits	2923	Target Neighborhood Hits	787	Shared Neighborhood Hits	749
SwissProt Accessions	P06803	Gene names	Pim1, Pim-1
Domain Architecture	No domain graphic available
Description	Proto-oncogene serine/threonine-protein kinase Pim-1 (EC 2.7.11.1).

STK38_MOUSE
θ value	1.2105e-12 (rank : 510)	NC score	0.703494 (rank : 296)
Query Neighborhood Hits	2923	Target Neighborhood Hits	838	Shared Neighborhood Hits	784
SwissProt Accessions	Q91VJ4	Gene names	Stk38, Ndr1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1 protein kinase) (Nuclear Dbf2-related kinase 1).

CD2L5_HUMAN
θ value	1.58096e-12 (rank : 511)	NC score	0.687613 (rank : 415)
Query Neighborhood Hits	2923	Target Neighborhood Hits	987	Shared Neighborhood Hits	829
SwissProt Accessions	Q14004, Q6DKQ9, Q75MH4, Q75MH5, Q96JN4, Q9H4A0, Q9H4A1, Q9UDR4	Gene names	CDC2L5, CDC2L, CHED, KIAA1791
Domain Architecture
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5) (Cholinesterase-related cell division controller).

CO7A1_HUMAN
θ value	1.58096e-12 (rank : 512)	NC score	0.172273 (rank : 1109)
Query Neighborhood Hits	2923	Target Neighborhood Hits	807	Shared Neighborhood Hits	313
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

DMPK_MOUSE
θ value	1.58096e-12 (rank : 513)	NC score	0.695962 (rank : 343)
Query Neighborhood Hits	2923	Target Neighborhood Hits	908	Shared Neighborhood Hits	821
SwissProt Accessions	P54265	Gene names	Dmpk, Dm15, Mdpk
Domain Architecture
Description	Myotonin-protein kinase (EC 2.7.11.1) (Myotonic dystrophy protein kinase) (MDPK) (DM-kinase) (DMK) (DMPK) (MT-PK).

FGFR4_MOUSE
θ value	1.58096e-12 (rank : 514)	NC score	0.665619 (rank : 512)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1026	Shared Neighborhood Hits	965
SwissProt Accessions	Q03142, Q5J7D9, Q8C3V5, Q8CIB8	Gene names	Fgfr4, Fgfr-4, Mpk-11
Domain Architecture
Description	Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1) (FGFR-4) (Protein-tyrosine kinase receptor MPK-11) (CD334 antigen).

ICK_HUMAN
θ value	1.58096e-12 (rank : 515)	NC score	0.700180 (rank : 317)
Query Neighborhood Hits	2923	Target Neighborhood Hits	867	Shared Neighborhood Hits	793
SwissProt Accessions	Q9UPZ9, O75985, Q5THL2, Q8IYH8, Q9BX17, Q9NYX3	Gene names	ICK, KIAA0936
Domain Architecture
Description	Serine/threonine-protein kinase ICK (EC 2.7.11.22) (Intestinal cell kinase) (hICK) (MAK-related kinase) (MRK) (Laryngeal cancer kinase 2) (LCK2).

M4K4_HUMAN
θ value	1.58096e-12 (rank : 516)	NC score	0.674672 (rank : 476)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1589	Shared Neighborhood Hits	1100
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

MAST1_HUMAN
θ value	1.58096e-12 (rank : 517)	NC score	0.704362 (rank : 291)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1146	Shared Neighborhood Hits	880
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MK12_HUMAN
θ value	1.58096e-12 (rank : 518)	NC score	0.693331 (rank : 362)
Query Neighborhood Hits	2923	Target Neighborhood Hits	830	Shared Neighborhood Hits	776
SwissProt Accessions	P53778, Q14260, Q99588, Q99672	Gene names	MAPK12, ERK6, SAPK3
Domain Architecture
Description	Mitogen-activated protein kinase 12 (EC 2.7.11.24) (Extracellular signal-regulated kinase 6) (ERK-6) (ERK5) (Stress-activated protein kinase 3) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma).

MK13_MOUSE
θ value	1.58096e-12 (rank : 519)	NC score	0.690649 (rank : 392)
Query Neighborhood Hits	2923	Target Neighborhood Hits	832	Shared Neighborhood Hits	778
SwissProt Accessions	Q9Z1B7, Q99M57	Gene names	Mapk13, Serk4
Domain Architecture
Description	Mitogen-activated protein kinase 13 (EC 2.7.11.24) (Stress-activated protein kinase 4) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta).

PFTK1_MOUSE
θ value	1.58096e-12 (rank : 520)	NC score	0.693296 (rank : 364)
Query Neighborhood Hits	2923	Target Neighborhood Hits	835	Shared Neighborhood Hits	781
SwissProt Accessions	O35495, O35848	Gene names	Pftk1
Domain Architecture
Description	Serine/threonine-protein kinase PFTAIRE-1 (EC 2.7.11.22).

CCRK_HUMAN
θ value	2.0648e-12 (rank : 521)	NC score	0.691460 (rank : 383)
Query Neighborhood Hits	2923	Target Neighborhood Hits	835	Shared Neighborhood Hits	777
SwissProt Accessions	Q8IZL9, Q5EDC4, Q5VYW1, Q9BUF4	Gene names	CCRK, CDCH
Domain Architecture	No domain graphic available
Description	Cell cycle-related kinase (EC 2.7.11.22) (Cyclin-kinase-activating kinase p42) (CDK-activating kinase p42) (CAK-kinase p42) (Cyclin- dependent protein kinase H).

CLK1_MOUSE
θ value	2.0648e-12 (rank : 522)	NC score	0.666851 (rank : 507)
Query Neighborhood Hits	2923	Target Neighborhood Hits	760	Shared Neighborhood Hits	737
SwissProt Accessions	P22518	Gene names	Clk1, Clk, Sty
Domain Architecture
Description	Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1) (Protein kinase STY).

CLK2_MOUSE
θ value	2.0648e-12 (rank : 523)	NC score	0.651912 (rank : 546)
Query Neighborhood Hits	2923	Target Neighborhood Hits	743	Shared Neighborhood Hits	728
SwissProt Accessions	O35491	Gene names	Clk2
Domain Architecture
Description	Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2).

HIPK1_HUMAN
θ value	2.0648e-12 (rank : 524)	NC score	0.674135 (rank : 481)
Query Neighborhood Hits	2923	Target Neighborhood Hits	843	Shared Neighborhood Hits	777
SwissProt Accessions	Q86Z02, O75125, Q8IYD7, Q8NDN5, Q8NEB6, Q8TBZ1	Gene names	HIPK1, KIAA0630
Domain Architecture
Description	Homeodomain-interacting protein kinase 1 (EC 2.7.11.1).

HIPK1_MOUSE
θ value	2.0648e-12 (rank : 525)	NC score	0.673932 (rank : 483)
Query Neighborhood Hits	2923	Target Neighborhood Hits	838	Shared Neighborhood Hits	774
SwissProt Accessions	O88904, Q80TV5, Q9QUQ8, Q9QZR3, Q9WVN7	Gene names	Hipk1, Kiaa0630, Myak, Nbak2
Domain Architecture
Description	Homeodomain-interacting protein kinase 1 (EC 2.7.11.1) (Protein kinase Myak) (Nuclear body-associated kinase 2).

MK06_MOUSE
θ value	2.0648e-12 (rank : 526)	NC score	0.680376 (rank : 461)
Query Neighborhood Hits	2923	Target Neighborhood Hits	818	Shared Neighborhood Hits	772
SwissProt Accessions	Q61532, Q497T9, Q6YKB0, Q7TT30, Q80XH5, Q922U4, Q9JLU6	Gene names	Mapk6, Erk3, Prkm4, Prkm6
Domain Architecture
Description	Mitogen-activated protein kinase 6 (EC 2.7.11.24) (Extracellular signal-regulated kinase 3) (ERK-3).

MK15_MOUSE
θ value	2.0648e-12 (rank : 527)	NC score	0.698585 (rank : 329)
Query Neighborhood Hits	2923	Target Neighborhood Hits	843	Shared Neighborhood Hits	780
SwissProt Accessions	Q80Y86	Gene names	Mapk15, Erk7
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 7).

NFH_MOUSE
θ value	2.0648e-12 (rank : 528)	NC score	0.084725 (rank : 1249)
Query Neighborhood Hits	2923	Target Neighborhood Hits	2247	Shared Neighborhood Hits	814
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

ST38L_MOUSE
θ value	2.0648e-12 (rank : 529)	NC score	0.699834 (rank : 318)
Query Neighborhood Hits	2923	Target Neighborhood Hits	821	Shared Neighborhood Hits	777
SwissProt Accessions	Q7TSE6, Q6P6K6, Q8BWK4	Gene names	Stk38l, Ndr2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 38-like (EC 2.7.11.1) (NDR2 protein kinase) (Nuclear Dbf2-related kinase 2).

TENA_MOUSE
θ value	2.0648e-12 (rank : 530)	NC score	0.138810 (rank : 1151)
Query Neighborhood Hits	2923	Target Neighborhood Hits	596	Shared Neighborhood Hits	188
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

CLK3_HUMAN
θ value	2.69671e-12 (rank : 531)	NC score	0.642971 (rank : 565)
Query Neighborhood Hits	2923	Target Neighborhood Hits	748	Shared Neighborhood Hits	725
SwissProt Accessions	P49761, Q9BRS3, Q9BUJ7	Gene names	CLK3
Domain Architecture
Description	Dual specificity protein kinase CLK3 (EC 2.7.12.1) (CDC-like kinase 3).

CLK3_MOUSE
θ value	2.69671e-12 (rank : 532)	NC score	0.642456 (rank : 566)
Query Neighborhood Hits	2923	Target Neighborhood Hits	761	Shared Neighborhood Hits	728
SwissProt Accessions	O35492	Gene names	Clk3
Domain Architecture
Description	Dual specificity protein kinase CLK3 (EC 2.7.12.1) (CDC-like kinase 3).

CSF1R_MOUSE
θ value	2.69671e-12 (rank : 533)	NC score	0.588653 (rank : 668)
Query Neighborhood Hits	2923	Target Neighborhood Hits	983	Shared Neighborhood Hits	916
SwissProt Accessions	P09581, Q3U3P1, Q9DBH9	Gene names	Csf1r, Csfmr, Fms
Domain Architecture
Description	Macrophage colony-stimulating factor 1 receptor precursor (EC 2.7.10.1) (CSF-1-R) (Fms proto-oncogene) (c-fms) (CD115 antigen).

FGFR2_HUMAN
θ value	2.69671e-12 (rank : 534)	NC score	0.687328 (rank : 416)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1062	Shared Neighborhood Hits	993
SwissProt Accessions	P21802, P18443, Q01742, Q12922, Q14300, Q14301, Q14302, Q14303, Q14304, Q14305, Q14672, Q14718, Q14719, Q86YI4, Q96KL9, Q96KM0, Q96KM1, Q96KM2, Q9NZU2, Q9NZU3, Q9UD01, Q9UD02, Q9UIH3, Q9UIH4, Q9UIH5, Q9UIH6, Q9UIH7, Q9UIH8, Q9UM87, Q9UMC6, Q9UNS7, Q9UQH7, Q9UQH8, Q9UQH9, Q9UQI0	Gene names	FGFR2, BEK, KSAM
Domain Architecture
Description	Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor 2) (CD332 antigen).

LATS1_HUMAN
θ value	2.69671e-12 (rank : 535)	NC score	0.689633 (rank : 403)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1057	Shared Neighborhood Hits	895
SwissProt Accessions	O95835, Q6PKD0	Gene names	LATS1, WARTS
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts).

MAG_HUMAN
θ value	2.69671e-12 (rank : 536)	NC score	0.454189 (rank : 897)
Query Neighborhood Hits	2923	Target Neighborhood Hits	278	Shared Neighborhood Hits	269
SwissProt Accessions	P20916	Gene names	MAG
Domain Architecture
Description	Myelin-associated glycoprotein precursor (Siglec-4a).

MK06_HUMAN
θ value	2.69671e-12 (rank : 537)	NC score	0.680582 (rank : 457)
Query Neighborhood Hits	2923	Target Neighborhood Hits	815	Shared Neighborhood Hits	769
SwissProt Accessions	Q16659, Q68DH4, Q8IYN8	Gene names	MAPK6, ERK3, PRKM6
Domain Architecture
Description	Mitogen-activated protein kinase 6 (EC 2.7.11.24) (Extracellular signal-regulated kinase 3) (ERK-3) (MAP kinase isoform p97) (p97- MAPK).

OXSR1_HUMAN
θ value	2.69671e-12 (rank : 538)	NC score	0.698971 (rank : 324)
Query Neighborhood Hits	2923	Target Neighborhood Hits	874	Shared Neighborhood Hits	797
SwissProt Accessions	O95747, Q3LR53, Q7Z501, Q9UPQ1	Gene names	OXSR1, KIAA1101, OSR1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress- responsive 1 protein).

OXSR1_MOUSE
θ value	2.69671e-12 (rank : 539)	NC score	0.698719 (rank : 328)
Query Neighborhood Hits	2923	Target Neighborhood Hits	865	Shared Neighborhood Hits	793
SwissProt Accessions	Q6P9R2, Q8BVZ9, Q8C0B9	Gene names	Oxsr1, Osr1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress- responsive 1 protein).

MAST1_MOUSE
θ value	3.52202e-12 (rank : 540)	NC score	0.703881 (rank : 294)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1123	Shared Neighborhood Hits	863
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

NEK2_MOUSE
θ value	3.52202e-12 (rank : 541)	NC score	0.717670 (rank : 203)
Query Neighborhood Hits	2923	Target Neighborhood Hits	876	Shared Neighborhood Hits	788
SwissProt Accessions	O35942, O35959	Gene names	Nek2
Domain Architecture
Description	Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (NimA-related protein kinase 2).

ROBO4_HUMAN
θ value	3.52202e-12 (rank : 542)	NC score	0.470465 (rank : 882)
Query Neighborhood Hits	2923	Target Neighborhood Hits	364	Shared Neighborhood Hits	322
SwissProt Accessions	Q8WZ75, Q8TEG1, Q96JV6, Q9H718, Q9NWJ8	Gene names	ROBO4
Domain Architecture
Description	Roundabout homolog 4 precursor (Magic roundabout).

LATS2_HUMAN
θ value	4.59992e-12 (rank : 543)	NC score	0.685491 (rank : 425)
Query Neighborhood Hits	2923	Target Neighborhood Hits	884	Shared Neighborhood Hits	800
SwissProt Accessions	Q9NRM7, Q9P2X1	Gene names	LATS2, KPM
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein) (Warts-like kinase).

STK40_HUMAN
θ value	4.59992e-12 (rank : 544)	NC score	0.702857 (rank : 300)
Query Neighborhood Hits	2923	Target Neighborhood Hits	751	Shared Neighborhood Hits	718
SwissProt Accessions	Q8N2I9, Q5VTK8, Q5VTK9, Q6ZMN1, Q8N2J8, Q8N3I6, Q96HN6, Q96I44, Q9BSA3, Q9H7H6	Gene names	STK40, SHIK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 40 (EC 2.7.11.1) (SINK-homologous serine/threonine-protein kinase).

STK40_MOUSE
θ value	4.59992e-12 (rank : 545)	NC score	0.702624 (rank : 304)
Query Neighborhood Hits	2923	Target Neighborhood Hits	751	Shared Neighborhood Hits	717
SwissProt Accessions	Q7TNL3, Q3U3G3, Q811D6, Q8BKT1, Q9D7K3	Gene names	Stk40, Lyk4
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 40 (EC 2.7.11.1) (Serine/threonine- protein kinase lyk4).

TAOK1_MOUSE
θ value	4.59992e-12 (rank : 546)	NC score	0.663560 (rank : 518)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1720	Shared Neighborhood Hits	1145
SwissProt Accessions	Q5F2E8, Q69ZL2, Q8JZX2, Q91VG7	Gene names	Taok1, Kiaa1361
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1).

CCRK_MOUSE
θ value	6.00763e-12 (rank : 547)	NC score	0.690837 (rank : 390)
Query Neighborhood Hits	2923	Target Neighborhood Hits	832	Shared Neighborhood Hits	773
SwissProt Accessions	Q9JHU3, Q5EDC2	Gene names	Ccrk, Cdch
Domain Architecture	No domain graphic available
Description	Cell cycle-related kinase (EC 2.7.11.22) (Cyclin-kinase-activating kinase p42) (CDK-activating kinase p42) (CAK-kinase p42) (CDK-related protein kinase PNQLARE) (Cyclin-dependent protein kinase H).

CD2L5_MOUSE
θ value	6.00763e-12 (rank : 548)	NC score	0.688603 (rank : 410)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1011	Shared Neighborhood Hits	857
SwissProt Accessions	Q69ZA1, Q80V11, Q8BZG1, Q8K0A4	Gene names	Cdc2l5, Kiaa1791
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5).

CDK7_HUMAN
θ value	6.00763e-12 (rank : 549)	NC score	0.694981 (rank : 349)
Query Neighborhood Hits	2923	Target Neighborhood Hits	833	Shared Neighborhood Hits	773
SwissProt Accessions	P50613, Q9BS60, Q9UE19	Gene names	CDK7, MO15
Domain Architecture
Description	Cell division protein kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (CDK- activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 kDa protein kinase) (P39 Mo15) (STK1) (CAK1).

CDK7_MOUSE
θ value	6.00763e-12 (rank : 550)	NC score	0.694788 (rank : 351)
Query Neighborhood Hits	2923	Target Neighborhood Hits	835	Shared Neighborhood Hits	773
SwissProt Accessions	Q03147, Q99KK3	Gene names	Cdk7, Cdkn7, Crk4, Mo15, Mpk-7
Domain Architecture
Description	Cell division protein kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (CDK- activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 kDa protein kinase) (P39 Mo15) (Protein-tyrosine kinase MPK-7) (CR4 protein kinase) (CRK4).

FGFR2_MOUSE
θ value	6.00763e-12 (rank : 551)	NC score	0.682515 (rank : 447)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1062	Shared Neighborhood Hits	992
SwissProt Accessions	P21803, O55141, Q00389, Q61342	Gene names	Fgfr2, Bek, Ect1
Domain Architecture
Description	Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor) (CD332 antigen).

MAG_MOUSE
θ value	6.00763e-12 (rank : 552)	NC score	0.453748 (rank : 898)
Query Neighborhood Hits	2923	Target Neighborhood Hits	271	Shared Neighborhood Hits	262
SwissProt Accessions	P20917, P16880	Gene names	Mag
Domain Architecture
Description	Myelin-associated glycoprotein precursor (Siglec-4a).

MK08_HUMAN
θ value	6.00763e-12 (rank : 553)	NC score	0.683955 (rank : 437)
Query Neighborhood Hits	2923	Target Neighborhood Hits	834	Shared Neighborhood Hits	777
SwissProt Accessions	P45983, Q15709, Q15712, Q15713	Gene names	MAPK8, JNK1, PRKM8
Domain Architecture
Description	Mitogen-activated protein kinase 8 (EC 2.7.11.24) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1) (JNK-46).

MK08_MOUSE
θ value	6.00763e-12 (rank : 554)	NC score	0.684485 (rank : 432)
Query Neighborhood Hits	2923	Target Neighborhood Hits	834	Shared Neighborhood Hits	777
SwissProt Accessions	Q91Y86	Gene names	Mapk8, Jnk1, Prkm8
Domain Architecture
Description	Mitogen-activated protein kinase 8 (EC 2.7.11.24) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1).

STK10_HUMAN
θ value	6.00763e-12 (rank : 555)	NC score	0.682644 (rank : 445)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1921	Shared Neighborhood Hits	1213
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

TAOK1_HUMAN
θ value	6.00763e-12 (rank : 556)	NC score	0.663289 (rank : 519)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1734	Shared Neighborhood Hits	1154
SwissProt Accessions	Q7L7X3, Q96L75, Q9H2K7, Q9H7S5, Q9P2I6	Gene names	TAOK1, KIAA1361, MAP3K16
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1) (STE20-like kinase PSK2) (Kinase from chicken homolog B) (hKFC-B).

CD276_HUMAN
θ value	7.84624e-12 (rank : 557)	NC score	0.274297 (rank : 1018)
Query Neighborhood Hits	2923	Target Neighborhood Hits	261	Shared Neighborhood Hits	222
SwissProt Accessions	Q5ZPR3, Q6P5Y4, Q6UXI2, Q8NBI8, Q8NC34, Q8NCB6, Q9BXR1	Gene names	CD276, B7H3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3) (4Ig-B7-H3).

EPHA3_MOUSE
θ value	7.84624e-12 (rank : 558)	NC score	0.600191 (rank : 634)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1009	Shared Neighborhood Hits	889
SwissProt Accessions	P29319	Gene names	Epha3, Etk1, Mek4, Tyro4
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (MEK4).

FSTL5_HUMAN
θ value	7.84624e-12 (rank : 559)	NC score	0.415169 (rank : 928)
Query Neighborhood Hits	2923	Target Neighborhood Hits	347	Shared Neighborhood Hits	269
SwissProt Accessions	Q8N475, Q9NSW7, Q9ULF7	Gene names	FSTL5, KIAA1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5).

ROBO4_MOUSE
θ value	7.84624e-12 (rank : 560)	NC score	0.474904 (rank : 879)
Query Neighborhood Hits	2923	Target Neighborhood Hits	358	Shared Neighborhood Hits	310
SwissProt Accessions	Q8C310, Q9DBW1	Gene names	Robo4
Domain Architecture
Description	Roundabout homolog 4 precursor.

STK10_MOUSE
θ value	7.84624e-12 (rank : 561)	NC score	0.667967 (rank : 502)
Query Neighborhood Hits	2923	Target Neighborhood Hits	2132	Shared Neighborhood Hits	1268
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

TYRO3_HUMAN
θ value	7.84624e-12 (rank : 562)	NC score	0.656745 (rank : 533)
Query Neighborhood Hits	2923	Target Neighborhood Hits	995	Shared Neighborhood Hits	935
SwissProt Accessions	Q06418, O14953, Q86VR3	Gene names	TYRO3, BYK, DTK, RSE, SKY
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine- protein kinase DTK) (Protein-tyrosine kinase byk).

EPHA4_MOUSE
θ value	1.02475e-11 (rank : 563)	NC score	0.596460 (rank : 646)
Query Neighborhood Hits	2923	Target Neighborhood Hits	982	Shared Neighborhood Hits	868
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

FGFR3_HUMAN
θ value	1.02475e-11 (rank : 564)	NC score	0.682476 (rank : 449)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1042	Shared Neighborhood Hits	979
SwissProt Accessions	P22607, Q14308, Q16294, Q16608	Gene names	FGFR3, JTK4
Domain Architecture
Description	Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1) (FGFR-3) (CD333 antigen).

JAK1_HUMAN
θ value	1.02475e-11 (rank : 565)	NC score	0.611232 (rank : 614)
Query Neighborhood Hits	2923	Target Neighborhood Hits	858	Shared Neighborhood Hits	783
SwissProt Accessions	P23458	Gene names	JAK1, JAK1A
Domain Architecture
Description	Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1).

LATS2_MOUSE
θ value	1.02475e-11 (rank : 566)	NC score	0.684767 (rank : 430)
Query Neighborhood Hits	2923	Target Neighborhood Hits	879	Shared Neighborhood Hits	790
SwissProt Accessions	Q7TSJ6, Q8CDJ4, Q9JMI3	Gene names	Lats2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein).

M3K2_MOUSE
θ value	1.02475e-11 (rank : 567)	NC score	0.709072 (rank : 267)
Query Neighborhood Hits	2923	Target Neighborhood Hits	846	Shared Neighborhood Hits	786
SwissProt Accessions	Q61083	Gene names	Map3k2, Mekk2
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2).

M3K6_HUMAN
θ value	1.02475e-11 (rank : 568)	NC score	0.709128 (rank : 266)
Query Neighborhood Hits	2923	Target Neighborhood Hits	889	Shared Neighborhood Hits	811
SwissProt Accessions	O95382	Gene names	MAP3K6, MAPKKK6
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 6 (EC 2.7.11.25).

FGFR4_HUMAN
θ value	1.33837e-11 (rank : 569)	NC score	0.680929 (rank : 456)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1037	Shared Neighborhood Hits	976
SwissProt Accessions	P22455, O43785, Q14309	Gene names	FGFR4, JTK2, TKF
Domain Architecture
Description	Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1) (FGFR-4) (CD334 antigen).

CEA20_HUMAN
θ value	1.74796e-11 (rank : 570)	NC score	0.398917 (rank : 947)
Query Neighborhood Hits	2923	Target Neighborhood Hits	251	Shared Neighborhood Hits	232
SwissProt Accessions	Q6UY09	Gene names	CEACAM20
Domain Architecture	No domain graphic available
Description	Carcinoembryonic antigen-related cell adhesion molecule 20 precursor.

MASTL_HUMAN
θ value	1.74796e-11 (rank : 571)	NC score	0.699152 (rank : 322)
Query Neighborhood Hits	2923	Target Neighborhood Hits	894	Shared Neighborhood Hits	791
SwissProt Accessions	Q96GX5, Q5T8D5, Q5T8D7, Q8NCD6, Q96SJ5	Gene names	MASTL, THC2
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase-like (EC 2.7.11.1).

MUC18_HUMAN
θ value	1.74796e-11 (rank : 572)	NC score	0.419615 (rank : 920)
Query Neighborhood Hits	2923	Target Neighborhood Hits	275	Shared Neighborhood Hits	258
SwissProt Accessions	P43121, O95812, Q59E86, Q6PHR3, Q6ZTR2	Gene names	MCAM, MUC18
Domain Architecture
Description	Cell surface glycoprotein MUC18 precursor (Melanoma-associated antigen MUC18) (Melanoma cell adhesion molecule) (Melanoma-associated antigen A32) (S-endo 1 endothelial-associated antigen) (Cell surface glycoprotein P1H12) (CD146 antigen).

NPTN_HUMAN
θ value	1.74796e-11 (rank : 573)	NC score	0.408578 (rank : 941)
Query Neighborhood Hits	2923	Target Neighborhood Hits	212	Shared Neighborhood Hits	208
SwissProt Accessions	Q9Y639, Q59EJ9, Q6NVX7, Q9Y640	Gene names	NPTN, SDFR1, SDR1
Domain Architecture	No domain graphic available
Description	Neuroplastin precursor (Stromal cell-derived receptor 1) (SDR-1).

PECA1_HUMAN
θ value	1.74796e-11 (rank : 574)	NC score	0.271628 (rank : 1021)
Query Neighborhood Hits	2923	Target Neighborhood Hits	178	Shared Neighborhood Hits	170
SwissProt Accessions	P16284, Q6LDA9, Q8TBH1, Q96RF5, Q96RF6, Q9NP65, Q9NPB7, Q9NPG9, Q9NQS9, Q9NQT0, Q9NQT1, Q9NQT2	Gene names	PECAM1
Domain Architecture
Description	Platelet endothelial cell adhesion molecule precursor (PECAM-1) (EndoCAM) (GPIIA') (CD31 antigen).

CD2L7_HUMAN
θ value	2.28291e-11 (rank : 575)	NC score	0.694286 (rank : 353)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1275	Shared Neighborhood Hits	989
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

EPHA4_HUMAN
θ value	2.28291e-11 (rank : 576)	NC score	0.594954 (rank : 650)
Query Neighborhood Hits	2923	Target Neighborhood Hits	975	Shared Neighborhood Hits	865
SwissProt Accessions	P54764	Gene names	EPHA4, HEK8, SEK
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8).

EPHB1_HUMAN
θ value	2.28291e-11 (rank : 577)	NC score	0.600810 (rank : 632)
Query Neighborhood Hits	2923	Target Neighborhood Hits	988	Shared Neighborhood Hits	862
SwissProt Accessions	P54762, O43569, O95142, O95143	Gene names	EPHB1, EPHT2, NET
Domain Architecture
Description	Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK).

FSTL4_MOUSE
θ value	2.98157e-11 (rank : 578)	NC score	0.415019 (rank : 929)
Query Neighborhood Hits	2923	Target Neighborhood Hits	333	Shared Neighborhood Hits	266
SwissProt Accessions	Q5STE3, Q5DU03	Gene names	Fstl4, Kiaa1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4) (m- D/Bsp120I 1-1).

GRK7_HUMAN
θ value	2.98157e-11 (rank : 579)	NC score	0.705963 (rank : 285)
Query Neighborhood Hits	2923	Target Neighborhood Hits	820	Shared Neighborhood Hits	773
SwissProt Accessions	Q8WTQ7	Gene names	GRK7, GPRK7
Domain Architecture
Description	G protein-coupled receptor kinase 7 precursor (EC 2.7.11.16) (G protein-coupled receptor kinase GRK7).

HIPK2_HUMAN
θ value	2.98157e-11 (rank : 580)	NC score	0.673471 (rank : 485)
Query Neighborhood Hits	2923	Target Neighborhood Hits	845	Shared Neighborhood Hits	773
SwissProt Accessions	Q9H2X6, Q75MR7, Q8WWI4, Q9H2Y1	Gene names	HIPK2
Domain Architecture
Description	Homeodomain-interacting protein kinase 2 (EC 2.7.11.1) (hHIPk2).

HIPK2_MOUSE
θ value	2.98157e-11 (rank : 581)	NC score	0.672675 (rank : 487)
Query Neighborhood Hits	2923	Target Neighborhood Hits	871	Shared Neighborhood Hits	786
SwissProt Accessions	Q9QZR5, O88905, Q99P45, Q99P46, Q9D2E6, Q9D474, Q9EQL2, Q9QZR4	Gene names	Hipk2, Nbak1, Stank
Domain Architecture
Description	Homeodomain-interacting protein kinase 2 (EC 2.7.11.1) (Nuclear body- associated kinase 1) (Sialophorin tail-associated nuclear serine/threonine-protein kinase).

IKKE_HUMAN
θ value	2.98157e-11 (rank : 582)	NC score	0.709514 (rank : 263)
Query Neighborhood Hits	2923	Target Neighborhood Hits	837	Shared Neighborhood Hits	778
SwissProt Accessions	Q14164	Gene names	IKBKE, IKKE, IKKI, KIAA0151
Domain Architecture
Description	Inhibitor of nuclear factor kappa-B kinase epsilon subunit (EC 2.7.11.10) (I kappa-B kinase epsilon) (IkBKE) (IKK-epsilon) (IKK- E) (Inducible I kappa-B kinase) (IKK-i).

M3K8_MOUSE
θ value	2.98157e-11 (rank : 583)	NC score	0.703792 (rank : 295)
Query Neighborhood Hits	2923	Target Neighborhood Hits	815	Shared Neighborhood Hits	767
SwissProt Accessions	Q07174	Gene names	Map3k8, Cot
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 8 (EC 2.7.11.25) (COT proto-oncogene serine/threonine-protein kinase) (C-COT) (Cancer Osaka thyroid oncogene).

M4K5_HUMAN
θ value	2.98157e-11 (rank : 584)	NC score	0.683595 (rank : 439)
Query Neighborhood Hits	2923	Target Neighborhood Hits	845	Shared Neighborhood Hits	778
SwissProt Accessions	Q9Y4K4, Q8IYF6	Gene names	MAP4K5
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 5) (MEK kinase kinase 5) (MEKKK 5) (Kinase homologous to SPS1/STE20) (KHS).

MLTK_MOUSE
θ value	2.98157e-11 (rank : 585)	NC score	0.641175 (rank : 567)
Query Neighborhood Hits	2923	Target Neighborhood Hits	874	Shared Neighborhood Hits	779
SwissProt Accessions	Q9ESL4, Q3V1X8, Q8BR73, Q9ESL3	Gene names	Mltk
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif kinase ZAK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK).

NLK_HUMAN
θ value	2.98157e-11 (rank : 586)	NC score	0.683897 (rank : 438)
Query Neighborhood Hits	2923	Target Neighborhood Hits	840	Shared Neighborhood Hits	780
SwissProt Accessions	Q9UBE8, Q2PNI9, Q6P2A3	Gene names	NLK, LAK1
Domain Architecture	No domain graphic available
Description	Serine/threonine kinase NLK (EC 2.7.11.24) (Nemo-like kinase) (Protein LAK1).

NLK_MOUSE
θ value	2.98157e-11 (rank : 587)	NC score	0.683976 (rank : 436)
Query Neighborhood Hits	2923	Target Neighborhood Hits	839	Shared Neighborhood Hits	780
SwissProt Accessions	O54949, Q6PF98	Gene names	Nlk
Domain Architecture	No domain graphic available
Description	Serine/threonine kinase NLK (EC 2.7.11.24) (Nemo-like kinase).

PIM3_MOUSE
θ value	2.98157e-11 (rank : 588)	NC score	0.713910 (rank : 229)
Query Neighborhood Hits	2923	Target Neighborhood Hits	783	Shared Neighborhood Hits	747
SwissProt Accessions	P58750	Gene names	Pim3
Domain Architecture
Description	Serine/threonine-protein kinase Pim-3 (EC 2.7.11.1).

TSSK6_MOUSE
θ value	2.98157e-11 (rank : 589)	NC score	0.731461 (rank : 120)
Query Neighborhood Hits	2923	Target Neighborhood Hits	824	Shared Neighborhood Hits	783
SwissProt Accessions	Q925K9, Q5RL09, Q8C625	Gene names	Tssk6, Sstk
Domain Architecture	No domain graphic available
Description	Testis-specific serine/threonine-protein kinase 6 (EC 2.7.11.1) (TSSK- 6) (Small serine/threonine kinase) (Serine/threonine-protein kinase SSTK).

MK11_MOUSE
θ value	3.89403e-11 (rank : 590)	NC score	0.686627 (rank : 419)
Query Neighborhood Hits	2923	Target Neighborhood Hits	835	Shared Neighborhood Hits	783
SwissProt Accessions	Q9WUI1	Gene names	Mapk11, Prkm11
Domain Architecture
Description	Mitogen-activated protein kinase 11 (EC 2.7.11.24) (Mitogen-activated protein kinase p38 beta) (MAP kinase p38 beta) (p38B).

MYO3A_HUMAN
θ value	3.89403e-11 (rank : 591)	NC score	0.619606 (rank : 601)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1033	Shared Neighborhood Hits	883
SwissProt Accessions	Q8NEV4, Q8WX17, Q9NYS8	Gene names	MYO3A
Domain Architecture
Description	Myosin IIIA (EC 2.7.11.1).

TAOK3_HUMAN
θ value	3.89403e-11 (rank : 592)	NC score	0.668450 (rank : 500)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1494	Shared Neighborhood Hits	1078
SwissProt Accessions	Q9H2K8, Q658N1, Q8IUM4, Q9HC79, Q9NZM9, Q9UHG7	Gene names	TAOK3, DPK, JIK, KDS, MAP3K18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3) (Jun kinase-inhibitory kinase) (JNK/SAPK- inhibitory kinase) (Dendritic cell-derived protein kinase) (Cutaneous T-cell lymphoma tumor antigen HD-CL-09) (CTCL tumor antigen HD-CL-09) (Kinase from chicken homolog A) (hKFC-A).

CDK10_HUMAN
θ value	5.08577e-11 (rank : 593)	NC score	0.677495 (rank : 468)
Query Neighborhood Hits	2923	Target Neighborhood Hits	831	Shared Neighborhood Hits	779
SwissProt Accessions	Q15131, Q15130	Gene names	CDK10
Domain Architecture
Description	Cell division protein kinase 10 (EC 2.7.11.22) (Serine/threonine- protein kinase PISSLRE).

HIPK3_HUMAN
θ value	5.08577e-11 (rank : 594)	NC score	0.673732 (rank : 484)
Query Neighborhood Hits	2923	Target Neighborhood Hits	867	Shared Neighborhood Hits	772
SwissProt Accessions	Q9H422, O14632, Q2PBG4, Q2PBG5, Q92632, Q9HAS2	Gene names	HIPK3, DYRK6, FIST3, PKY
Domain Architecture	No domain graphic available
Description	Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Homolog of protein kinase YAK1) (Fas-interacting serine/threonine-protein kinase) (FIST) (Androgen receptor-interacting nuclear protein kinase) (ANPK).

JAM1_HUMAN
θ value	5.08577e-11 (rank : 595)	NC score	0.433176 (rank : 904)
Query Neighborhood Hits	2923	Target Neighborhood Hits	294	Shared Neighborhood Hits	280
SwissProt Accessions	Q9Y624	Gene names	F11R, JAM1, JCAM
Domain Architecture
Description	Junctional adhesion molecule A precursor (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (Platelet adhesion molecule 1) (PAM-1) (Platelet F11 receptor) (CD321 antigen).

LATS1_MOUSE
θ value	5.08577e-11 (rank : 596)	NC score	0.686986 (rank : 418)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1027	Shared Neighborhood Hits	883
SwissProt Accessions	Q8BYR2, Q9Z0W4	Gene names	Lats1, Warts
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase).

M4K5_MOUSE
θ value	5.08577e-11 (rank : 597)	NC score	0.684271 (rank : 435)
Query Neighborhood Hits	2923	Target Neighborhood Hits	839	Shared Neighborhood Hits	774
SwissProt Accessions	Q8BPM2, Q6PEQ2, Q8C3U5, Q8CGF3, Q99LM7, Q9CX73	Gene names	Map4k5
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 5) (MEK kinase kinase 5) (MEKKK 5).

MLTK_HUMAN
θ value	5.08577e-11 (rank : 598)	NC score	0.640781 (rank : 568)
Query Neighborhood Hits	2923	Target Neighborhood Hits	911	Shared Neighborhood Hits	791
SwissProt Accessions	Q9NYL2, Q53SX1, Q580W8, Q59GY5, Q86YW8, Q9HCC4, Q9HCC5, Q9HDD2, Q9NYE9	Gene names	MLTK, ZAK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Cervical cancer suppressor gene 4 protein).

MYO3A_MOUSE
θ value	5.08577e-11 (rank : 599)	NC score	0.623732 (rank : 595)
Query Neighborhood Hits	2923	Target Neighborhood Hits	902	Shared Neighborhood Hits	819
SwissProt Accessions	Q8K3H5	Gene names	Myo3a
Domain Architecture
Description	Myosin IIIA (EC 2.7.11.1).

COEA1_HUMAN
θ value	6.64225e-11 (rank : 600)	NC score	0.180134 (rank : 1104)
Query Neighborhood Hits	2923	Target Neighborhood Hits	427	Shared Neighborhood Hits	208
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

COEA1_MOUSE
θ value	6.64225e-11 (rank : 601)	NC score	0.203583 (rank : 1075)
Query Neighborhood Hits	2923	Target Neighborhood Hits	402	Shared Neighborhood Hits	202
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

EPHA1_MOUSE
θ value	6.64225e-11 (rank : 602)	NC score	0.561666 (rank : 720)
Query Neighborhood Hits	2923	Target Neighborhood Hits	958	Shared Neighborhood Hits	815
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

HIPK3_MOUSE
θ value	6.64225e-11 (rank : 603)	NC score	0.675390 (rank : 471)
Query Neighborhood Hits	2923	Target Neighborhood Hits	857	Shared Neighborhood Hits	773
SwissProt Accessions	Q9ERH7, O88906, Q9QZR2	Gene names	Hipk3, Fist3
Domain Architecture	No domain graphic available
Description	Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Fas- interacting serine/threonine-protein kinase) (FIST) (Nuclear body- associated kinase 3) (Nbak3) (Androgen receptor-interacting nuclear protein kinase) (ANPK).

M4K4_MOUSE
θ value	6.64225e-11 (rank : 604)	NC score	0.669713 (rank : 493)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1560	Shared Neighborhood Hits	1088
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

MK07_HUMAN
θ value	6.64225e-11 (rank : 605)	NC score	0.688368 (rank : 411)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1087	Shared Neighborhood Hits	898
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

MK07_MOUSE
θ value	6.64225e-11 (rank : 606)	NC score	0.689142 (rank : 406)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1054	Shared Neighborhood Hits	890
SwissProt Accessions	Q9WVS8	Gene names	Mapk7, Erk5
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase).

PIM3_HUMAN
θ value	6.64225e-11 (rank : 607)	NC score	0.715515 (rank : 219)
Query Neighborhood Hits	2923	Target Neighborhood Hits	789	Shared Neighborhood Hits	751
SwissProt Accessions	Q86V86, Q68BM2	Gene names	PIM3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase Pim-3 (EC 2.7.11.1).

PSG8_HUMAN
θ value	6.64225e-11 (rank : 608)	NC score	0.301544 (rank : 1000)
Query Neighborhood Hits	2923	Target Neighborhood Hits	239	Shared Neighborhood Hits	231
SwissProt Accessions	Q9UQ74, O60410	Gene names	PSG8
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 8 precursor (PSBG-8).

TBK1_MOUSE
θ value	6.64225e-11 (rank : 609)	NC score	0.711129 (rank : 244)
Query Neighborhood Hits	2923	Target Neighborhood Hits	893	Shared Neighborhood Hits	825
SwissProt Accessions	Q9WUN2, Q9CT90, Q9DC03	Gene names	Tbk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (TANK-binding kinase 1) (T2K).

CDK3_MOUSE
θ value	8.67504e-11 (rank : 610)	NC score	0.696858 (rank : 338)
Query Neighborhood Hits	2923	Target Neighborhood Hits	829	Shared Neighborhood Hits	778
SwissProt Accessions	Q80YP0	Gene names	Cdk3
Domain Architecture	No domain graphic available
Description	Truncated cell division protein kinase 3 homolog.

COCA1_HUMAN
θ value	8.67504e-11 (rank : 611)	NC score	0.230266 (rank : 1047)
Query Neighborhood Hits	2923	Target Neighborhood Hits	458	Shared Neighborhood Hits	238
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

EPHA5_HUMAN
θ value	8.67504e-11 (rank : 612)	NC score	0.599370 (rank : 638)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1009	Shared Neighborhood Hits	883
SwissProt Accessions	P54756	Gene names	EPHA5, EHK1, HEK7
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein- tyrosine kinase HEK7).

GSK3B_HUMAN
θ value	8.67504e-11 (rank : 613)	NC score	0.691958 (rank : 377)
Query Neighborhood Hits	2923	Target Neighborhood Hits	801	Shared Neighborhood Hits	758
SwissProt Accessions	P49841, Q9BWH3, Q9UL47	Gene names	GSK3B
Domain Architecture
Description	Glycogen synthase kinase-3 beta (EC 2.7.11.26) (GSK-3 beta).

GSK3B_MOUSE
θ value	8.67504e-11 (rank : 614)	NC score	0.691964 (rank : 376)
Query Neighborhood Hits	2923	Target Neighborhood Hits	800	Shared Neighborhood Hits	758
SwissProt Accessions	Q9WV60	Gene names	Gsk3b
Domain Architecture
Description	Glycogen synthase kinase-3 beta (EC 2.7.11.26) (GSK-3 beta).

ITB4_HUMAN
θ value	8.67504e-11 (rank : 615)	NC score	0.215087 (rank : 1065)
Query Neighborhood Hits	2923	Target Neighborhood Hits	458	Shared Neighborhood Hits	211
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

MASTL_MOUSE
θ value	8.67504e-11 (rank : 616)	NC score	0.698460 (rank : 330)
Query Neighborhood Hits	2923	Target Neighborhood Hits	862	Shared Neighborhood Hits	785
SwissProt Accessions	Q8C0P0, Q5RJW0, Q6NXX9, Q8BVF3, Q9CZH9, Q9D9V0	Gene names	Mastl
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase-like (EC 2.7.11.1).

PGFRA_HUMAN
θ value	8.67504e-11 (rank : 617)	NC score	0.610137 (rank : 616)
Query Neighborhood Hits	2923	Target Neighborhood Hits	980	Shared Neighborhood Hits	904
SwissProt Accessions	P16234, Q96KZ7	Gene names	PDGFRA
Domain Architecture
Description	Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen).

TAOK3_MOUSE
θ value	8.67504e-11 (rank : 618)	NC score	0.668895 (rank : 497)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1458	Shared Neighborhood Hits	1065
SwissProt Accessions	Q8BYC6, Q3V3B3	Gene names	Taok3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3).

TYRO3_MOUSE
θ value	8.67504e-11 (rank : 619)	NC score	0.654376 (rank : 537)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1007	Shared Neighborhood Hits	943
SwissProt Accessions	P55144, O09070, O09080, P70285, Q60752, Q62482, Q62483, Q62484, Q78E85, Q78E87	Gene names	Tyro3, Dtk, Rse
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase DTK) (TK19-2) (Etk2/tyro3).

EPHA7_HUMAN
θ value	1.133e-10 (rank : 620)	NC score	0.608211 (rank : 620)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1053	Shared Neighborhood Hits	890
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

FSTL5_MOUSE
θ value	1.133e-10 (rank : 621)	NC score	0.409943 (rank : 938)
Query Neighborhood Hits	2923	Target Neighborhood Hits	355	Shared Neighborhood Hits	267
SwissProt Accessions	Q8BFR2, Q80TG3, Q8C4T3	Gene names	Fstl5, Kiaa1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5) (m- D/Bsp120I 1-2).

GSK3A_HUMAN
θ value	1.133e-10 (rank : 622)	NC score	0.693245 (rank : 365)
Query Neighborhood Hits	2923	Target Neighborhood Hits	835	Shared Neighborhood Hits	769
SwissProt Accessions	P49840, O14959	Gene names	GSK3A
Domain Architecture
Description	Glycogen synthase kinase-3 alpha (EC 2.7.11.26) (GSK-3 alpha).

MK09_HUMAN
θ value	1.133e-10 (rank : 623)	NC score	0.687769 (rank : 413)
Query Neighborhood Hits	2923	Target Neighborhood Hits	842	Shared Neighborhood Hits	786
SwissProt Accessions	P45984, Q15708, Q15710, Q15711, Q8N5C5	Gene names	MAPK9, JNK2, PRKM9
Domain Architecture
Description	Mitogen-activated protein kinase 9 (EC 2.7.11.24) (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2) (JNK-55).

MK10_HUMAN
θ value	1.133e-10 (rank : 624)	NC score	0.681977 (rank : 451)
Query Neighborhood Hits	2923	Target Neighborhood Hits	836	Shared Neighborhood Hits	776
SwissProt Accessions	P53779, Q15707	Gene names	MAPK10, JNK3, JNK3A, PRKM10
Domain Architecture
Description	Mitogen-activated protein kinase 10 (EC 2.7.11.24) (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3) (MAP kinase p49 3F12).

RAF1_HUMAN
θ value	1.133e-10 (rank : 625)	NC score	0.645618 (rank : 561)
Query Neighborhood Hits	2923	Target Neighborhood Hits	886	Shared Neighborhood Hits	787
SwissProt Accessions	P04049	Gene names	RAF1, RAF
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

TAOK2_HUMAN
θ value	1.133e-10 (rank : 626)	NC score	0.680404 (rank : 460)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1172	Shared Neighborhood Hits	954
SwissProt Accessions	Q9UL54, O94957, Q6UW73, Q7LC09, Q9NSW2	Gene names	TAOK2, KIAA0881, MAP3K17, PSK, PSK1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Thousand and one amino acid protein 2) (Prostate-derived STE20-like kinase 1) (PSK-1) (Kinase from chicken homolog C) (hKFC-C).

EPHA3_HUMAN
θ value	1.47974e-10 (rank : 627)	NC score	0.604148 (rank : 628)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1005	Shared Neighborhood Hits	887
SwissProt Accessions	P29320, Q9H2V3, Q9H2V4	Gene names	EPHA3, ETK, ETK1, HEK
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4).

LCK_MOUSE
θ value	1.47974e-10 (rank : 628)	NC score	0.576666 (rank : 692)
Query Neighborhood Hits	2923	Target Neighborhood Hits	981	Shared Neighborhood Hits	778
SwissProt Accessions	P06240, Q61794, Q61795, Q62320, Q91X65	Gene names	Lck, Lsk-t
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK).

RAF1_MOUSE
θ value	1.47974e-10 (rank : 629)	NC score	0.646460 (rank : 557)
Query Neighborhood Hits	2923	Target Neighborhood Hits	886	Shared Neighborhood Hits	790
SwissProt Accessions	Q99N57, Q91WH1	Gene names	Raf1, Craf
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

TAOK2_MOUSE
θ value	1.47974e-10 (rank : 630)	NC score	0.674737 (rank : 474)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1373	Shared Neighborhood Hits	1042
SwissProt Accessions	Q6ZQ29, Q7TSS8	Gene names	Taok2, Kiaa0881
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Thousand and one amino acid protein 2).

TRIB2_MOUSE
θ value	1.47974e-10 (rank : 631)	NC score	0.670590 (rank : 491)
Query Neighborhood Hits	2923	Target Neighborhood Hits	653	Shared Neighborhood Hits	635
SwissProt Accessions	Q8K4K3, Q8K017, Q8R2V8	Gene names	Trib2
Domain Architecture	No domain graphic available
Description	Tribbles homolog 2 (TRB-2).

TSSK6_HUMAN
θ value	1.47974e-10 (rank : 632)	NC score	0.730684 (rank : 126)
Query Neighborhood Hits	2923	Target Neighborhood Hits	824	Shared Neighborhood Hits	784
SwissProt Accessions	Q9BXA6, Q6ZMC4, Q96LJ4	Gene names	TSSK6, FKSG82, SSTK
Domain Architecture	No domain graphic available
Description	Testis-specific serine/threonine-protein kinase 6 (EC 2.7.11.1) (TSSK- 6) (Small serine/threonine kinase) (Serine/threonine-protein kinase SSTK).

TXK_HUMAN
θ value	1.47974e-10 (rank : 633)	NC score	0.590836 (rank : 660)
Query Neighborhood Hits	2923	Target Neighborhood Hits	971	Shared Neighborhood Hits	775
SwissProt Accessions	P42681, Q14220	Gene names	TXK
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2).

JAK1_MOUSE
θ value	1.9326e-10 (rank : 634)	NC score	0.605056 (rank : 625)
Query Neighborhood Hits	2923	Target Neighborhood Hits	854	Shared Neighborhood Hits	780
SwissProt Accessions	P52332, Q62126	Gene names	Jak1
Domain Architecture
Description	Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1).

MK04_HUMAN
θ value	1.9326e-10 (rank : 635)	NC score	0.690356 (rank : 395)
Query Neighborhood Hits	2923	Target Neighborhood Hits	837	Shared Neighborhood Hits	780
SwissProt Accessions	P31152	Gene names	MAPK4, ERK4, PRKM4
Domain Architecture
Description	Mitogen-activated protein kinase 4 (EC 2.7.11.24) (Extracellular signal-regulated kinase 4) (ERK-4) (MAP kinase isoform p63) (p63- MAPK).

MK10_MOUSE
θ value	1.9326e-10 (rank : 636)	NC score	0.681285 (rank : 455)
Query Neighborhood Hits	2923	Target Neighborhood Hits	849	Shared Neighborhood Hits	780
SwissProt Accessions	Q61831, Q9R0U6	Gene names	Mapk10, Jnk3, Prkm10, Serk2
Domain Architecture
Description	Mitogen-activated protein kinase 10 (EC 2.7.11.24) (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3) (MAP kinase p49 3F12).

TBK1_HUMAN
θ value	1.9326e-10 (rank : 637)	NC score	0.710547 (rank : 254)
Query Neighborhood Hits	2923	Target Neighborhood Hits	861	Shared Neighborhood Hits	799
SwissProt Accessions	Q9UHD2, Q8IYV3, Q9NUJ5	Gene names	TBK1, NAK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (TANK-binding kinase 1) (T2K) (NF-kappa-B-activating kinase).

DDR2_HUMAN
θ value	2.52405e-10 (rank : 638)	NC score	0.549425 (rank : 757)
Query Neighborhood Hits	2923	Target Neighborhood Hits	818	Shared Neighborhood Hits	733
SwissProt Accessions	Q16832	Gene names	DDR2, NTRKR3, TKT, TYRO10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

TRIB2_HUMAN
θ value	2.52405e-10 (rank : 639)	NC score	0.670939 (rank : 490)
Query Neighborhood Hits	2923	Target Neighborhood Hits	657	Shared Neighborhood Hits	640
SwissProt Accessions	Q92519	Gene names	TRIB2, TRB2
Domain Architecture	No domain graphic available
Description	Tribbles homolog 2 (TRB-2).

IKKE_MOUSE
θ value	3.29651e-10 (rank : 640)	NC score	0.708345 (rank : 275)
Query Neighborhood Hits	2923	Target Neighborhood Hits	848	Shared Neighborhood Hits	785
SwissProt Accessions	Q9R0T8	Gene names	Ikbke, Ikke, Ikki
Domain Architecture
Description	Inhibitor of nuclear factor kappa-B kinase epsilon subunit (EC 2.7.11.10) (I kappa-B kinase epsilon) (IkBKE) (IKK-epsilon) (IKK- E) (Inducible I kappa-B kinase) (IKK-i).

K1802_MOUSE
θ value	3.29651e-10 (rank : 641)	NC score	0.039529 (rank : 1848)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1596	Shared Neighborhood Hits	405
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

KSYK_HUMAN
θ value	3.29651e-10 (rank : 642)	NC score	0.601998 (rank : 630)
Query Neighborhood Hits	2923	Target Neighborhood Hits	901	Shared Neighborhood Hits	763
SwissProt Accessions	P43405	Gene names	SYK
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

MERTK_HUMAN
θ value	3.29651e-10 (rank : 643)	NC score	0.613277 (rank : 610)
Query Neighborhood Hits	2923	Target Neighborhood Hits	988	Shared Neighborhood Hits	923
SwissProt Accessions	Q12866, Q9HBB4	Gene names	MERTK, MER
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

MK11_HUMAN
θ value	3.29651e-10 (rank : 644)	NC score	0.681832 (rank : 452)
Query Neighborhood Hits	2923	Target Neighborhood Hits	823	Shared Neighborhood Hits	776
SwissProt Accessions	Q15759, O00284, O15472, Q2XNF2	Gene names	MAPK11, PRKM11, SAPK2
Domain Architecture
Description	Mitogen-activated protein kinase 11 (EC 2.7.11.24) (Mitogen-activated protein kinase p38 beta) (MAP kinase p38 beta) (p38b) (p38-2) (Stress- activated protein kinase 2).

PGFRB_MOUSE
θ value	3.29651e-10 (rank : 645)	NC score	0.599387 (rank : 637)
Query Neighborhood Hits	2923	Target Neighborhood Hits	960	Shared Neighborhood Hits	897
SwissProt Accessions	P05622	Gene names	Pdgfrb, Pdgfr
Domain Architecture
Description	Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen).

ROR1_MOUSE
θ value	3.29651e-10 (rank : 646)	NC score	0.639787 (rank : 572)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1025	Shared Neighborhood Hits	937
SwissProt Accessions	Q9Z139	Gene names	Ror1, Ntrkr1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1) (mROR1).

SRMS_MOUSE
θ value	3.29651e-10 (rank : 647)	NC score	0.587422 (rank : 670)
Query Neighborhood Hits	2923	Target Neighborhood Hits	964	Shared Neighborhood Hits	782
SwissProt Accessions	Q62270, Q62360, Q923M5	Gene names	Srms, Srm
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70).

TXND2_MOUSE
θ value	3.29651e-10 (rank : 648)	NC score	0.079448 (rank : 1266)
Query Neighborhood Hits	2923	Target Neighborhood Hits	828	Shared Neighborhood Hits	348
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

EPHA7_MOUSE
θ value	4.30538e-10 (rank : 649)	NC score	0.607997 (rank : 621)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1025	Shared Neighborhood Hits	885
SwissProt Accessions	Q61772, Q61505, Q61773, Q61774	Gene names	Epha7, Ebk, Ehk3, Mdk1
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1).

LCK_HUMAN
θ value	4.30538e-10 (rank : 650)	NC score	0.572544 (rank : 704)
Query Neighborhood Hits	2923	Target Neighborhood Hits	987	Shared Neighborhood Hits	782
SwissProt Accessions	P06239, P07100, Q12850, Q13152, Q5TDH8, Q5TDH9, Q96DW4, Q9NYT8	Gene names	LCK
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell- specific protein-tyrosine kinase).

MP2K5_MOUSE
θ value	4.30538e-10 (rank : 651)	NC score	0.693766 (rank : 357)
Query Neighborhood Hits	2923	Target Neighborhood Hits	840	Shared Neighborhood Hits	780
SwissProt Accessions	Q9WVS7, Q8CFM3, Q8K360, Q9D222	Gene names	Map2k5, Mek5, Mkk5, Prkmk5
Domain Architecture	No domain graphic available
Description	Dual specificity mitogen-activated protein kinase kinase 5 (EC 2.7.12.2) (MAP kinase kinase 5) (MAPKK 5) (MAPK/ERK kinase 5).

SRMS_HUMAN
θ value	4.30538e-10 (rank : 652)	NC score	0.583027 (rank : 685)
Query Neighborhood Hits	2923	Target Neighborhood Hits	946	Shared Neighborhood Hits	781
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).

TRIB1_HUMAN
θ value	4.30538e-10 (rank : 653)	NC score	0.650459 (rank : 548)
Query Neighborhood Hits	2923	Target Neighborhood Hits	598	Shared Neighborhood Hits	581
SwissProt Accessions	Q96RU8, O15180, Q9H2Y8	Gene names	TRIB1, C8FW, GIG2, TRB1
Domain Architecture	No domain graphic available
Description	Tribbles homolog 1 (TRB-1) (SKIP1) (G-protein-coupled receptor-induced protein 2) (GIG-2).

ZAP70_HUMAN
θ value	4.30538e-10 (rank : 654)	NC score	0.599778 (rank : 636)
Query Neighborhood Hits	2923	Target Neighborhood Hits	893	Shared Neighborhood Hits	765
SwissProt Accessions	P43403	Gene names	ZAP70, SRK
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

JAM1_MOUSE
θ value	5.62301e-10 (rank : 655)	NC score	0.420000 (rank : 918)
Query Neighborhood Hits	2923	Target Neighborhood Hits	287	Shared Neighborhood Hits	275
SwissProt Accessions	O88792	Gene names	F11r, Jam1, Jcam, Jcam1
Domain Architecture
Description	Junctional adhesion molecule A precursor (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (CD321 antigen).

NTRK3_HUMAN
θ value	5.62301e-10 (rank : 656)	NC score	0.633348 (rank : 583)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1115	Shared Neighborhood Hits	930
SwissProt Accessions	Q16288, Q12827, Q16289	Gene names	NTRK3, TRKC
Domain Architecture
Description	NT-3 growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C).

ROR2_HUMAN
θ value	5.62301e-10 (rank : 657)	NC score	0.633213 (rank : 584)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1014	Shared Neighborhood Hits	924
SwissProt Accessions	Q01974, Q59GF5, Q5SPI5, Q9HAY7, Q9HB61	Gene names	ROR2, NTRKR2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2).

CI094_HUMAN
θ value	7.34386e-10 (rank : 658)	NC score	0.350354 (rank : 975)
Query Neighborhood Hits	2923	Target Neighborhood Hits	310	Shared Neighborhood Hits	241
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

FAK1_HUMAN
θ value	7.34386e-10 (rank : 659)	NC score	0.599158 (rank : 639)
Query Neighborhood Hits	2923	Target Neighborhood Hits	850	Shared Neighborhood Hits	775
SwissProt Accessions	Q05397, Q14291, Q9UD85	Gene names	PTK2, FAK, FAK1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK) (Protein- tyrosine kinase 2).

HIPK4_HUMAN
θ value	7.34386e-10 (rank : 660)	NC score	0.688661 (rank : 409)
Query Neighborhood Hits	2923	Target Neighborhood Hits	799	Shared Neighborhood Hits	760
SwissProt Accessions	Q8NE63	Gene names	HIPK4
Domain Architecture	No domain graphic available
Description	Homeodomain-interacting protein kinase 4 (EC 2.7.11.1).

PSG7_HUMAN
θ value	7.34386e-10 (rank : 661)	NC score	0.291473 (rank : 1009)
Query Neighborhood Hits	2923	Target Neighborhood Hits	239	Shared Neighborhood Hits	229
SwissProt Accessions	Q13046, Q15232	Gene names	PSG7
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 7 precursor (PSBG-7).

SIG11_HUMAN
θ value	7.34386e-10 (rank : 662)	NC score	0.385108 (rank : 951)
Query Neighborhood Hits	2923	Target Neighborhood Hits	273	Shared Neighborhood Hits	255
SwissProt Accessions	Q96RL6	Gene names	SIGLEC11
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 11 precursor (Siglec-11) (Sialic acid-binding lectin 11).

BMX_HUMAN
θ value	9.59137e-10 (rank : 663)	NC score	0.587417 (rank : 671)
Query Neighborhood Hits	2923	Target Neighborhood Hits	942	Shared Neighborhood Hits	773
SwissProt Accessions	P51813, O60564, Q12871	Gene names	BMX
Domain Architecture
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38).

CEAM8_HUMAN
θ value	9.59137e-10 (rank : 664)	NC score	0.312611 (rank : 997)
Query Neighborhood Hits	2923	Target Neighborhood Hits	264	Shared Neighborhood Hits	248
SwissProt Accessions	P31997, O60399, Q16574	Gene names	CEACAM8, CGM6
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 8 precursor (Carcinoembryonic antigen CGM6) (Nonspecific cross-reacting antigen NCA-95) (CD67 antigen) (CD66b antigen).

MK04_MOUSE
θ value	9.59137e-10 (rank : 665)	NC score	0.688669 (rank : 408)
Query Neighborhood Hits	2923	Target Neighborhood Hits	852	Shared Neighborhood Hits	778
SwissProt Accessions	Q6P5G0	Gene names	Mapk4, Erk4, Prkm4
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 4 (EC 2.7.11.24) (Extracellular signal-regulated kinase 4) (ERK-4).

MK09_MOUSE
θ value	9.59137e-10 (rank : 666)	NC score	0.684278 (rank : 434)
Query Neighborhood Hits	2923	Target Neighborhood Hits	843	Shared Neighborhood Hits	785
SwissProt Accessions	Q9WTU6, Q8C097, Q8VDD2, Q9WTU4, Q9WTU5	Gene names	Mapk9, Jnk2, Prkm9
Domain Architecture
Description	Mitogen-activated protein kinase 9 (EC 2.7.11.24) (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2).

PRRT3_HUMAN
θ value	9.59137e-10 (rank : 667)	NC score	0.071844 (rank : 1297)
Query Neighborhood Hits	2923	Target Neighborhood Hits	998	Shared Neighborhood Hits	335
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

WNK1_MOUSE
θ value	9.59137e-10 (rank : 668)	NC score	0.658753 (rank : 529)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1179	Shared Neighborhood Hits	866
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

EPHA8_HUMAN
θ value	1.25267e-09 (rank : 669)	NC score	0.594390 (rank : 651)
Query Neighborhood Hits	2923	Target Neighborhood Hits	956	Shared Neighborhood Hits	871
SwissProt Accessions	P29322, Q9NUA9, Q9P269	Gene names	EPHA8, EEK, KIAA1459
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3).

M3K1_MOUSE
θ value	1.25267e-09 (rank : 670)	NC score	0.712378 (rank : 239)
Query Neighborhood Hits	2923	Target Neighborhood Hits	952	Shared Neighborhood Hits	820
SwissProt Accessions	P53349, Q60831, Q9R0U3, Q9R256	Gene names	Map3k1, Mekk, Mekk1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1).

NTRK2_HUMAN
θ value	1.25267e-09 (rank : 671)	NC score	0.657981 (rank : 532)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1081	Shared Neighborhood Hits	942
SwissProt Accessions	Q16620, Q16675, Q8WXJ6	Gene names	NTRK2, TRKB
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB) (Trk-B).

PSG2_HUMAN
θ value	1.25267e-09 (rank : 672)	NC score	0.286632 (rank : 1011)
Query Neighborhood Hits	2923	Target Neighborhood Hits	229	Shared Neighborhood Hits	224
SwissProt Accessions	P11465, Q8TCD9, Q9UEA4, Q9UQ78	Gene names	PSG2
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 2 precursor (PSBG-2) (Pregnancy-specific beta-1 glycoprotein E) (PS-beta-E).

SIG10_HUMAN
θ value	1.25267e-09 (rank : 673)	NC score	0.379473 (rank : 960)
Query Neighborhood Hits	2923	Target Neighborhood Hits	363	Shared Neighborhood Hits	289
SwissProt Accessions	Q96LC7, Q6UXI8, Q96G54, Q96LC8	Gene names	SIGLEC10, SLG2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 10 precursor (Siglec-10) (Siglec- like protein 2).

TRIB1_MOUSE
θ value	1.25267e-09 (rank : 674)	NC score	0.648864 (rank : 549)
Query Neighborhood Hits	2923	Target Neighborhood Hits	593	Shared Neighborhood Hits	579
SwissProt Accessions	Q8K4K4, Q8BFS7, Q8BJR9, Q8BZX3, Q91W04	Gene names	Trib1, Trb1
Domain Architecture	No domain graphic available
Description	Tribbles homolog 1 (TRB-1).

WNK1_HUMAN
θ value	1.25267e-09 (rank : 675)	NC score	0.660280 (rank : 526)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1158	Shared Neighborhood Hits	880
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

WNK4_MOUSE
θ value	1.25267e-09 (rank : 676)	NC score	0.659767 (rank : 527)
Query Neighborhood Hits	2923	Target Neighborhood Hits	961	Shared Neighborhood Hits	799
SwissProt Accessions	Q80UE6, Q4VAC1, Q80XB5, Q80XN2, Q8R0N0, Q8R340	Gene names	Wnk4, Prkwnk4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

AL2S7_HUMAN
θ value	1.63604e-09 (rank : 677)	NC score	0.684606 (rank : 431)
Query Neighborhood Hits	2923	Target Neighborhood Hits	831	Shared Neighborhood Hits	775
SwissProt Accessions	Q96Q40, Q4ZG86, Q53TV1	Gene names	ALS2CR7
Domain Architecture
Description	Serine/threonine-protein kinase ALS2CR7 (EC 2.7.11.22) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein).

EPHA8_MOUSE
θ value	1.63604e-09 (rank : 678)	NC score	0.591888 (rank : 655)
Query Neighborhood Hits	2923	Target Neighborhood Hits	969	Shared Neighborhood Hits	869
SwissProt Accessions	O09127	Gene names	Epha8, Eek
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase).

FES_HUMAN
θ value	1.63604e-09 (rank : 679)	NC score	0.611492 (rank : 613)
Query Neighborhood Hits	2923	Target Neighborhood Hits	978	Shared Neighborhood Hits	805
SwissProt Accessions	P07332	Gene names	FES, FPS
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

JAM2_HUMAN
θ value	1.63604e-09 (rank : 680)	NC score	0.416531 (rank : 924)
Query Neighborhood Hits	2923	Target Neighborhood Hits	304	Shared Neighborhood Hits	296
SwissProt Accessions	P57087, Q6UXG6, Q6YNC1	Gene names	JAM2, C21orf43, VEJAM
Domain Architecture
Description	Junctional adhesion molecule B precursor (JAM-B) (Junctional adhesion molecule 2) (Vascular endothelial junction-associated molecule) (VE- JAM) (CD322 antigen).

KSYK_MOUSE
θ value	1.63604e-09 (rank : 681)	NC score	0.601838 (rank : 631)
Query Neighborhood Hits	2923	Target Neighborhood Hits	944	Shared Neighborhood Hits	779
SwissProt Accessions	P48025	Gene names	Syk
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

MUC18_MOUSE
θ value	1.63604e-09 (rank : 682)	NC score	0.412930 (rank : 934)
Query Neighborhood Hits	2923	Target Neighborhood Hits	292	Shared Neighborhood Hits	262
SwissProt Accessions	Q8R2Y2, Q9EPF1, Q9ESS7, Q9JHQ2, Q9JHQ3	Gene names	Mcam, Muc18
Domain Architecture	No domain graphic available
Description	Cell surface glycoprotein MUC18 precursor (Melanoma-associated antigen MUC18) (Melanoma cell adhesion molecule) (Gicerin).

NTRK2_MOUSE
θ value	1.63604e-09 (rank : 683)	NC score	0.658135 (rank : 531)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1088	Shared Neighborhood Hits	942
SwissProt Accessions	P15209, Q3TUF9, Q80WU0, Q91XJ9	Gene names	Ntrk2, Trkb
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B).

PRP4B_HUMAN
θ value	1.63604e-09 (rank : 684)	NC score	0.668737 (rank : 499)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1030	Shared Neighborhood Hits	883
SwissProt Accessions	Q13523, Q8TDP2, Q96QT7, Q9UEE6	Gene names	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (PRP4 kinase).

PRP4B_MOUSE
θ value	1.63604e-09 (rank : 685)	NC score	0.667377 (rank : 505)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1040	Shared Neighborhood Hits	884
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

ROS_HUMAN
θ value	1.63604e-09 (rank : 686)	NC score	0.598182 (rank : 642)
Query Neighborhood Hits	2923	Target Neighborhood Hits	907	Shared Neighborhood Hits	831
SwissProt Accessions	P08922, Q15368	Gene names	ROS1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ROS precursor (EC 2.7.10.1) (c- ros-1).

STK39_HUMAN
θ value	1.63604e-09 (rank : 687)	NC score	0.697444 (rank : 336)
Query Neighborhood Hits	2923	Target Neighborhood Hits	882	Shared Neighborhood Hits	796
SwissProt Accessions	Q9UEW8, O14774, Q9UER4	Gene names	STK39, SPAK
Domain Architecture
Description	STE20/SPS1-related proline-alanine-rich protein kinase (EC 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39) (DCHT).

STK39_MOUSE
θ value	1.63604e-09 (rank : 688)	NC score	0.697905 (rank : 332)
Query Neighborhood Hits	2923	Target Neighborhood Hits	915	Shared Neighborhood Hits	810
SwissProt Accessions	Q9Z1W9, Q80W13	Gene names	Stk39, Spak
Domain Architecture
Description	STE20/SPS1-related proline-alanine-rich protein kinase (EC 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39).

TXK_MOUSE
θ value	1.63604e-09 (rank : 689)	NC score	0.579694 (rank : 689)
Query Neighborhood Hits	2923	Target Neighborhood Hits	980	Shared Neighborhood Hits	767
SwissProt Accessions	P42682	Gene names	Txk, Rlk
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18) (Resting lymphocyte kinase).

ZAP70_MOUSE
θ value	1.63604e-09 (rank : 690)	NC score	0.598602 (rank : 640)
Query Neighborhood Hits	2923	Target Neighborhood Hits	905	Shared Neighborhood Hits	773
SwissProt Accessions	P43404	Gene names	Zap70, Srk, Zap-70
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

BRAF1_HUMAN
θ value	2.13673e-09 (rank : 691)	NC score	0.643374 (rank : 564)
Query Neighborhood Hits	2923	Target Neighborhood Hits	883	Shared Neighborhood Hits	781
SwissProt Accessions	P15056, Q13878, Q9Y6T3	Gene names	BRAF, BRAF1, RAFB1
Domain Architecture
Description	B-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1).

EPHB2_MOUSE
θ value	2.13673e-09 (rank : 692)	NC score	0.591192 (rank : 658)
Query Neighborhood Hits	2923	Target Neighborhood Hits	982	Shared Neighborhood Hits	858
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

EPHB4_HUMAN
θ value	2.13673e-09 (rank : 693)	NC score	0.596688 (rank : 645)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1056	Shared Neighborhood Hits	878
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

IL6RB_HUMAN
θ value	2.13673e-09 (rank : 694)	NC score	0.246518 (rank : 1034)
Query Neighborhood Hits	2923	Target Neighborhood Hits	181	Shared Neighborhood Hits	152
SwissProt Accessions	P40189, Q9UQ41	Gene names	IL6ST
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin M receptor) (CD130 antigen) (CDw130).

JAM3_MOUSE
θ value	2.13673e-09 (rank : 695)	NC score	0.414777 (rank : 930)
Query Neighborhood Hits	2923	Target Neighborhood Hits	286	Shared Neighborhood Hits	266
SwissProt Accessions	Q9D8B7, Q8BT59, Q9D1M9, Q9EPK4	Gene names	Jam3
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule C precursor (JAM-C) (Junctional adhesion molecule 3) (JAM-3) (JAM-2).

LAD1_MOUSE
θ value	2.13673e-09 (rank : 696)	NC score	0.105966 (rank : 1191)
Query Neighborhood Hits	2923	Target Neighborhood Hits	391	Shared Neighborhood Hits	234
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

MP2K5_HUMAN
θ value	2.13673e-09 (rank : 697)	NC score	0.688925 (rank : 407)
Query Neighborhood Hits	2923	Target Neighborhood Hits	837	Shared Neighborhood Hits	776
SwissProt Accessions	Q13163	Gene names	MAP2K5, MEK5, MKK5, PRKMK5
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 5 (EC 2.7.12.2) (MAP kinase kinase 5) (MAPKK 5) (MAPK/ERK kinase 5).

BMX_MOUSE
θ value	2.79066e-09 (rank : 698)	NC score	0.587028 (rank : 673)
Query Neighborhood Hits	2923	Target Neighborhood Hits	912	Shared Neighborhood Hits	764
SwissProt Accessions	P97504	Gene names	Bmx
Domain Architecture	No domain graphic available
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein homolog).

CDK6_MOUSE
θ value	2.79066e-09 (rank : 699)	NC score	0.693755 (rank : 359)
Query Neighborhood Hits	2923	Target Neighborhood Hits	837	Shared Neighborhood Hits	782
SwissProt Accessions	Q64261, Q9R1D2, Q9R1D3	Gene names	Cdk6, Crk2
Domain Architecture
Description	Cell division protein kinase 6 (EC 2.7.11.22) (Serine/threonine- protein kinase PLSTIRE) (CRK2).

FAK1_MOUSE
θ value	2.79066e-09 (rank : 700)	NC score	0.598555 (rank : 641)
Query Neighborhood Hits	2923	Target Neighborhood Hits	850	Shared Neighborhood Hits	770
SwissProt Accessions	P34152, O08578	Gene names	Ptk2, Fadk, Fak, Fak1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK).

JAK2_MOUSE
θ value	2.79066e-09 (rank : 701)	NC score	0.623204 (rank : 596)
Query Neighborhood Hits	2923	Target Neighborhood Hits	839	Shared Neighborhood Hits	778
SwissProt Accessions	Q62120, Q62124	Gene names	Jak2
Domain Architecture
Description	Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2).

JAK3_HUMAN
θ value	2.79066e-09 (rank : 702)	NC score	0.619701 (rank : 600)
Query Neighborhood Hits	2923	Target Neighborhood Hits	827	Shared Neighborhood Hits	767
SwissProt Accessions	P52333, Q13259, Q13260, Q13611, Q9Y6S2	Gene names	JAK3
Domain Architecture
Description	Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK).

KIT_HUMAN
θ value	2.79066e-09 (rank : 703)	NC score	0.586199 (rank : 674)
Query Neighborhood Hits	2923	Target Neighborhood Hits	953	Shared Neighborhood Hits	886
SwissProt Accessions	P10721, Q9UM99	Gene names	KIT
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

PDK1L_HUMAN
θ value	2.79066e-09 (rank : 704)	NC score	0.703055 (rank : 297)
Query Neighborhood Hits	2923	Target Neighborhood Hits	821	Shared Neighborhood Hits	766
SwissProt Accessions	Q8N165, Q5T2I0, Q8NDB3	Gene names	PDIK1L, CLIK1L
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PDIK1L (EC 2.7.11.1) (PDLIM1- interacting kinase 1-like).

PGFRA_MOUSE
θ value	2.79066e-09 (rank : 705)	NC score	0.607034 (rank : 622)
Query Neighborhood Hits	2923	Target Neighborhood Hits	975	Shared Neighborhood Hits	905
SwissProt Accessions	P26618, Q62046	Gene names	Pdgfra
Domain Architecture
Description	Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen).

PGFRB_HUMAN
θ value	2.79066e-09 (rank : 706)	NC score	0.595048 (rank : 649)
Query Neighborhood Hits	2923	Target Neighborhood Hits	962	Shared Neighborhood Hits	898
SwissProt Accessions	P09619, Q8N5L4	Gene names	PDGFRB
Domain Architecture
Description	Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen).

PTK6_HUMAN
θ value	2.79066e-09 (rank : 707)	NC score	0.606009 (rank : 624)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1020	Shared Neighborhood Hits	788
SwissProt Accessions	Q13882	Gene names	PTK6, BRK
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK).

PTK6_MOUSE
θ value	2.79066e-09 (rank : 708)	NC score	0.604913 (rank : 626)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1026	Shared Neighborhood Hits	791
SwissProt Accessions	Q64434	Gene names	Ptk6, Sik
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related intestinal kinase).

PTPRJ_HUMAN
θ value	2.79066e-09 (rank : 709)	NC score	0.112741 (rank : 1178)
Query Neighborhood Hits	2923	Target Neighborhood Hits	207	Shared Neighborhood Hits	122
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

CDK6_HUMAN
θ value	3.64472e-09 (rank : 710)	NC score	0.693612 (rank : 360)
Query Neighborhood Hits	2923	Target Neighborhood Hits	837	Shared Neighborhood Hits	782
SwissProt Accessions	Q00534	Gene names	CDK6
Domain Architecture
Description	Cell division protein kinase 6 (EC 2.7.11.22) (Serine/threonine- protein kinase PLSTIRE).

DDR2_MOUSE
θ value	3.64472e-09 (rank : 711)	NC score	0.553214 (rank : 750)
Query Neighborhood Hits	2923	Target Neighborhood Hits	813	Shared Neighborhood Hits	733
SwissProt Accessions	Q62371	Gene names	Ddr2, Ntrkr3, Tkt, Tyro10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

EPHB2_HUMAN
θ value	3.64472e-09 (rank : 712)	NC score	0.591006 (rank : 659)
Query Neighborhood Hits	2923	Target Neighborhood Hits	983	Shared Neighborhood Hits	858
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

EPHB3_HUMAN
θ value	3.64472e-09 (rank : 713)	NC score	0.589061 (rank : 665)
Query Neighborhood Hits	2923	Target Neighborhood Hits	996	Shared Neighborhood Hits	873
SwissProt Accessions	P54753, Q7Z740	Gene names	EPHB3, ETK2, HEK2
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2).

JAK2_HUMAN
θ value	3.64472e-09 (rank : 714)	NC score	0.624339 (rank : 593)
Query Neighborhood Hits	2923	Target Neighborhood Hits	847	Shared Neighborhood Hits	781
SwissProt Accessions	O60674, O14636, O75297	Gene names	JAK2
Domain Architecture
Description	Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2).

JAM3_HUMAN
θ value	3.64472e-09 (rank : 715)	NC score	0.410858 (rank : 936)
Query Neighborhood Hits	2923	Target Neighborhood Hits	271	Shared Neighborhood Hits	262
SwissProt Accessions	Q9BX67, Q8WWL8, Q96FL1	Gene names	JAM3
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule C precursor (JAM-C) (Junctional adhesion molecule 3) (JAM-3) (JAM-2).

PSG1_HUMAN
θ value	3.64472e-09 (rank : 716)	NC score	0.285345 (rank : 1012)
Query Neighborhood Hits	2923	Target Neighborhood Hits	232	Shared Neighborhood Hits	223
SwissProt Accessions	P11464, O75236, P11462, P11463, Q15231, Q15241, Q15243, Q16660, Q9P1W5, Q9UQ79	Gene names	PSG1, B1G1, PSGGA
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 1 precursor (PSBG-1) (Pregnancy-specific beta-1 glycoprotein C/D) (PS-beta-C/D) (Fetal liver non-specific cross-reactive antigen 1/2) (FL-NCA-1/2) (PSG95) (CD66f antigen).

EPHA6_HUMAN
θ value	4.76016e-09 (rank : 717)	NC score	0.547325 (rank : 764)
Query Neighborhood Hits	2923	Target Neighborhood Hits	959	Shared Neighborhood Hits	838
SwissProt Accessions	Q9UF33	Gene names	EPHA6, EHK2
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

EPHB4_MOUSE
θ value	4.76016e-09 (rank : 718)	NC score	0.600117 (rank : 635)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1013	Shared Neighborhood Hits	871
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

FES_MOUSE
θ value	4.76016e-09 (rank : 719)	NC score	0.612898 (rank : 611)
Query Neighborhood Hits	2923	Target Neighborhood Hits	980	Shared Neighborhood Hits	823
SwissProt Accessions	P16879, Q62122	Gene names	Fes, Fps
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

KIT_MOUSE
θ value	4.76016e-09 (rank : 720)	NC score	0.589756 (rank : 663)
Query Neighborhood Hits	2923	Target Neighborhood Hits	949	Shared Neighborhood Hits	888
SwissProt Accessions	P05532, Q61415, Q61416, Q61417, Q6LEE9	Gene names	Kit, Sl
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

M3K13_HUMAN
θ value	4.76016e-09 (rank : 721)	NC score	0.668361 (rank : 501)
Query Neighborhood Hits	2923	Target Neighborhood Hits	911	Shared Neighborhood Hits	799
SwissProt Accessions	O43283	Gene names	MAP3K13, LZK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Mixed lineage kinase) (MLK) (Leucine zipper-bearing kinase).

NFH_HUMAN
θ value	4.76016e-09 (rank : 722)	NC score	0.071604 (rank : 1299)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1242	Shared Neighborhood Hits	592
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PDK1L_MOUSE
θ value	4.76016e-09 (rank : 723)	NC score	0.702994 (rank : 298)
Query Neighborhood Hits	2923	Target Neighborhood Hits	821	Shared Neighborhood Hits	766
SwissProt Accessions	Q8QZR7, Q3URF0, Q8BKB3	Gene names	Pdik1l
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PDIK1L (EC 2.7.11.1) (PDLIM1- interacting kinase 1-like).

ROR2_MOUSE
θ value	4.76016e-09 (rank : 724)	NC score	0.618283 (rank : 603)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1000	Shared Neighborhood Hits	907
SwissProt Accessions	Q9Z138	Gene names	Ror2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2) (mROR2).

TIE2_HUMAN
θ value	4.76016e-09 (rank : 725)	NC score	0.624978 (rank : 591)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1192	Shared Neighborhood Hits	907
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

TLK2_HUMAN
θ value	4.76016e-09 (rank : 726)	NC score	0.702782 (rank : 302)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1044	Shared Neighborhood Hits	878
SwissProt Accessions	Q86UE8, Q9UKI7, Q9Y4F7	Gene names	TLK2
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (Tousled- like kinase 2) (PKU-alpha).

TLK2_MOUSE
θ value	4.76016e-09 (rank : 727)	NC score	0.702489 (rank : 305)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1088	Shared Neighborhood Hits	913
SwissProt Accessions	O55047, Q9D5Y5	Gene names	Tlk2
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (Tousled- like kinase 2).

DDR1_HUMAN
θ value	6.21693e-09 (rank : 728)	NC score	0.527287 (rank : 805)
Query Neighborhood Hits	2923	Target Neighborhood Hits	819	Shared Neighborhood Hits	732
SwissProt Accessions	Q08345, Q14196, Q16562, Q5ST12, Q9UD37	Gene names	DDR1, CAK, EDDR1, RTK6, TRKE
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (TRK E) (Protein-tyrosine kinase RTK 6) (HGK2) (CD167a antigen).

LRFN3_MOUSE
θ value	6.21693e-09 (rank : 729)	NC score	0.240488 (rank : 1041)
Query Neighborhood Hits	2923	Target Neighborhood Hits	455	Shared Neighborhood Hits	247
SwissProt Accessions	Q8BLY3	Gene names	Lrfn3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 3 precursor.

MYO3B_HUMAN
θ value	6.21693e-09 (rank : 730)	NC score	0.614127 (rank : 609)
Query Neighborhood Hits	2923	Target Neighborhood Hits	923	Shared Neighborhood Hits	818
SwissProt Accessions	Q8WXR4, Q8IX64, Q8IX65, Q8IX66, Q8IX67, Q8IX68	Gene names	MYO3B
Domain Architecture
Description	Myosin IIIB (EC 2.7.11.1).

TLK1_HUMAN
θ value	6.21693e-09 (rank : 731)	NC score	0.701169 (rank : 311)
Query Neighborhood Hits	2923	Target Neighborhood Hits	967	Shared Neighborhood Hits	842
SwissProt Accessions	Q9UKI8, Q14150, Q8N591, Q9NYH2, Q9Y4F6	Gene names	TLK1, KIAA0137
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1) (Tousled- like kinase 1) (PKU-beta).

TLK1_MOUSE
θ value	6.21693e-09 (rank : 732)	NC score	0.700934 (rank : 313)
Query Neighborhood Hits	2923	Target Neighborhood Hits	947	Shared Neighborhood Hits	821
SwissProt Accessions	Q8C0V0	Gene names	Tlk1
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1) (Tousled- like kinase 1).

TNK1_HUMAN
θ value	6.21693e-09 (rank : 733)	NC score	0.575751 (rank : 694)
Query Neighborhood Hits	2923	Target Neighborhood Hits	815	Shared Neighborhood Hits	739
SwissProt Accessions	Q13470, O95364, Q8IYI4	Gene names	TNK1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1).

TYK2_HUMAN
θ value	6.21693e-09 (rank : 734)	NC score	0.617601 (rank : 604)
Query Neighborhood Hits	2923	Target Neighborhood Hits	841	Shared Neighborhood Hits	778
SwissProt Accessions	P29597, Q6QB10, Q96CH0	Gene names	TYK2
Domain Architecture
Description	Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2).

JAK3_MOUSE
θ value	8.11959e-09 (rank : 735)	NC score	0.625994 (rank : 590)
Query Neighborhood Hits	2923	Target Neighborhood Hits	821	Shared Neighborhood Hits	762
SwissProt Accessions	Q62137, Q61746, Q61747	Gene names	Jak3
Domain Architecture
Description	Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3).

JAM2_MOUSE
θ value	8.11959e-09 (rank : 736)	NC score	0.405521 (rank : 943)
Query Neighborhood Hits	2923	Target Neighborhood Hits	292	Shared Neighborhood Hits	276
SwissProt Accessions	Q9JI59, Q8C5K9, Q8CE95	Gene names	Jam2, Vejam
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule B precursor (JAM-B) (Junctional adhesion molecule 2) (Vascular endothelial junction-associated molecule) (VE- JAM) (CD322 antigen).

PSG4_HUMAN
θ value	8.11959e-09 (rank : 737)	NC score	0.295919 (rank : 1005)
Query Neighborhood Hits	2923	Target Neighborhood Hits	243	Shared Neighborhood Hits	233
SwissProt Accessions	Q00888, Q13047, Q13048, Q15234, Q15240, Q9UQ76	Gene names	PSG4, CGM4, PSG9
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 4 precursor (PSBG-4) (PSBG-9).

ROR1_HUMAN
θ value	8.11959e-09 (rank : 738)	NC score	0.638624 (rank : 575)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1018	Shared Neighborhood Hits	929
SwissProt Accessions	Q01973, Q92776	Gene names	ROR1, NTRKR1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1).

WNK3_HUMAN
θ value	8.11959e-09 (rank : 739)	NC score	0.662935 (rank : 521)
Query Neighborhood Hits	2923	Target Neighborhood Hits	948	Shared Neighborhood Hits	785
SwissProt Accessions	Q9BYP7, Q9HCK6	Gene names	WNK3, KIAA1566, PRKWNK3
Domain Architecture
Description	Serine/threonine-protein kinase WNK3 (EC 2.7.11.1) (Protein kinase with no lysine 3) (Protein kinase, lysine-deficient 3).

EPHA5_MOUSE
θ value	1.06045e-08 (rank : 740)	NC score	0.600809 (rank : 633)
Query Neighborhood Hits	2923	Target Neighborhood Hits	950	Shared Neighborhood Hits	863
SwissProt Accessions	Q60629	Gene names	Epha5, Bsk, Cek7, Ehk1
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7).

FAK2_MOUSE
θ value	1.06045e-08 (rank : 741)	NC score	0.589210 (rank : 664)
Query Neighborhood Hits	2923	Target Neighborhood Hits	851	Shared Neighborhood Hits	765
SwissProt Accessions	Q9QVP9	Gene names	Ptk2b, Fak2, Pyk2, Raftk
Domain Architecture	No domain graphic available
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

MERTK_MOUSE
θ value	1.06045e-08 (rank : 742)	NC score	0.616444 (rank : 606)
Query Neighborhood Hits	2923	Target Neighborhood Hits	974	Shared Neighborhood Hits	903
SwissProt Accessions	Q60805, Q62194	Gene names	Mertk, Mer
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

NRK_HUMAN
θ value	1.06045e-08 (rank : 743)	NC score	0.682498 (rank : 448)
Query Neighborhood Hits	2923	Target Neighborhood Hits	931	Shared Neighborhood Hits	818
SwissProt Accessions	Q7Z2Y5, Q32ND6, Q5H9K2, Q6ZMP2	Gene names	NRK
Domain Architecture	No domain graphic available
Description	Nik-related protein kinase (EC 2.7.11.1).

ARBK2_HUMAN
θ value	1.38499e-08 (rank : 744)	NC score	0.697645 (rank : 334)
Query Neighborhood Hits	2923	Target Neighborhood Hits	849	Shared Neighborhood Hits	781
SwissProt Accessions	P35626, Q9UGW9	Gene names	ADRBK2, BARK2, GRK3
Domain Architecture
Description	Beta-adrenergic receptor kinase 2 (EC 2.7.11.15) (Beta-ARK-2) (G- protein-coupled receptor kinase 3).

EPHB3_MOUSE
θ value	1.38499e-08 (rank : 745)	NC score	0.588665 (rank : 667)
Query Neighborhood Hits	2923	Target Neighborhood Hits	996	Shared Neighborhood Hits	874
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

FAK2_HUMAN
θ value	1.38499e-08 (rank : 746)	NC score	0.584927 (rank : 680)
Query Neighborhood Hits	2923	Target Neighborhood Hits	847	Shared Neighborhood Hits	761
SwissProt Accessions	Q14289, Q13475, Q14290, Q16709	Gene names	PTK2B, FAK2, PYK2, RAFTK
Domain Architecture
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

FCGR1_HUMAN
θ value	1.38499e-08 (rank : 747)	NC score	0.189781 (rank : 1097)
Query Neighborhood Hits	2923	Target Neighborhood Hits	145	Shared Neighborhood Hits	126
SwissProt Accessions	P12314, P12315, Q92495, Q92663	Gene names	FCGR1A, FCG1, FCGR1, IGFR1
Domain Architecture
Description	High affinity immunoglobulin gamma Fc receptor I precursor (Fc-gamma RI) (FcRI) (IgG Fc receptor I) (CD64 antigen).

MDC1_MOUSE
θ value	1.38499e-08 (rank : 748)	NC score	0.093819 (rank : 1224)
Query Neighborhood Hits	2923	Target Neighborhood Hits	998	Shared Neighborhood Hits	424
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

PSG10_HUMAN
θ value	1.38499e-08 (rank : 749)	NC score	0.278645 (rank : 1016)
Query Neighborhood Hits	2923	Target Neighborhood Hits	227	Shared Neighborhood Hits	218
SwissProt Accessions	Q15235, O75244, Q15224	Gene names	PSG10, PSG12
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 10 precursor (PSBG-10) (PSBG- 12).

PSG6_HUMAN
θ value	1.38499e-08 (rank : 750)	NC score	0.281174 (rank : 1014)
Query Neighborhood Hits	2923	Target Neighborhood Hits	231	Shared Neighborhood Hits	220
SwissProt Accessions	Q00889	Gene names	PSG6, CGM3, PSGGB
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 6 precursor (PSBG-6).

PSG9_HUMAN
θ value	1.38499e-08 (rank : 751)	NC score	0.273848 (rank : 1019)
Query Neighborhood Hits	2923	Target Neighborhood Hits	221	Shared Neighborhood Hits	214
SwissProt Accessions	Q00887, Q15236, Q15237, Q8WW78, Q9UQ73	Gene names	PSG9, PSG11
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 9 precursor (PSBG-9) (Pregnancy-specific glycoprotein 9) (Pregnancy-specific beta-1 glycoprotein B) (PS-beta-B) (PS34) (Pregnancy-specific glycoprotein 7) (PSG7).

TIE1_MOUSE
θ value	1.38499e-08 (rank : 752)	NC score	0.621926 (rank : 597)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1266	Shared Neighborhood Hits	948
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

BASI_HUMAN
θ value	1.80886e-08 (rank : 753)	NC score	0.377039 (rank : 962)
Query Neighborhood Hits	2923	Target Neighborhood Hits	211	Shared Neighborhood Hits	205
SwissProt Accessions	P35613, Q7Z796, Q8IZL7	Gene names	BSG
Domain Architecture
Description	Basigin precursor (Leukocyte activation antigen M6) (Collagenase stimulatory factor) (Extracellular matrix metalloproteinase inducer) (EMMPRIN) (5F7) (Tumor cell-derived collagenase stimulatory factor) (TCSF) (OK blood group antigen) (CD147 antigen).

COKA1_HUMAN
θ value	1.80886e-08 (rank : 754)	NC score	0.166636 (rank : 1115)
Query Neighborhood Hits	2923	Target Neighborhood Hits	403	Shared Neighborhood Hits	180
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

CXAR_HUMAN
θ value	1.80886e-08 (rank : 755)	NC score	0.278133 (rank : 1017)
Query Neighborhood Hits	2923	Target Neighborhood Hits	245	Shared Neighborhood Hits	218
SwissProt Accessions	P78310, O00694, Q8WWT6, Q8WWT7, Q8WWT8, Q9UKV4	Gene names	CXADR, CAR
Domain Architecture
Description	Coxsackievirus and adenovirus receptor precursor (Coxsackievirus B- adenovirus receptor) (hCAR) (CVB3-binding protein) (HCVADR).

EMB_MOUSE
θ value	1.80886e-08 (rank : 756)	NC score	0.210042 (rank : 1066)
Query Neighborhood Hits	2923	Target Neighborhood Hits	83	Shared Neighborhood Hits	82
SwissProt Accessions	P21995, Q3UFF1, Q8C2J8, Q8C543, Q96C38	Gene names	Emb, Gp70
Domain Architecture
Description	Embigin precursor (Teratocarcinoma glycoprotein Gp-70).

M3KL4_HUMAN
θ value	1.80886e-08 (rank : 757)	NC score	0.638942 (rank : 573)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1087	Shared Neighborhood Hits	862
SwissProt Accessions	Q5TCX8, Q5TCX7, Q5TCX9, Q8WWN1, Q8WWN2, Q96JM1	Gene names	MLK4, KIAA1804
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase 4).

MDC1_HUMAN
θ value	1.80886e-08 (rank : 758)	NC score	0.104674 (rank : 1198)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1446	Shared Neighborhood Hits	567
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

DDR1_MOUSE
θ value	2.36244e-08 (rank : 759)	NC score	0.529623 (rank : 803)
Query Neighborhood Hits	2923	Target Neighborhood Hits	818	Shared Neighborhood Hits	731
SwissProt Accessions	Q03146	Gene names	Ddr1, Cak, Eddr1, Mpk6
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (Protein-tyrosine kinase MPK-6) (CD167a antigen).

IL6RB_MOUSE
θ value	2.36244e-08 (rank : 760)	NC score	0.224101 (rank : 1055)
Query Neighborhood Hits	2923	Target Neighborhood Hits	168	Shared Neighborhood Hits	147
SwissProt Accessions	Q00560	Gene names	Il6st
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (CD130 antigen).

LU_HUMAN
θ value	2.36244e-08 (rank : 761)	NC score	0.440216 (rank : 902)
Query Neighborhood Hits	2923	Target Neighborhood Hits	283	Shared Neighborhood Hits	266
SwissProt Accessions	P50895, Q86VC7	Gene names	BCAM, LU, MSK19
Domain Architecture
Description	Lutheran blood group glycoprotein precursor (B-CAM cell surface glycoprotein) (Auberger B antigen) (F8/G253 antigen) (CD239 antigen).

BTK_HUMAN
θ value	3.08544e-08 (rank : 762)	NC score	0.585125 (rank : 678)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1026	Shared Neighborhood Hits	785
SwissProt Accessions	Q06187	Gene names	BTK, AGMX1, ATK, BPK
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK).

EPHA2_HUMAN
θ value	3.08544e-08 (rank : 763)	NC score	0.590631 (rank : 661)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1021	Shared Neighborhood Hits	866
SwissProt Accessions	P29317	Gene names	EPHA2, ECK
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase).

LRFN5_MOUSE
θ value	3.08544e-08 (rank : 764)	NC score	0.228177 (rank : 1052)
Query Neighborhood Hits	2923	Target Neighborhood Hits	472	Shared Neighborhood Hits	253
SwissProt Accessions	Q8BXA0, Q8BJH4, Q8BZL0	Gene names	Lrfn5
Domain Architecture
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 5 precursor.

LYN_MOUSE
θ value	3.08544e-08 (rank : 765)	NC score	0.583788 (rank : 683)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1023	Shared Neighborhood Hits	799
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

PSG11_HUMAN
θ value	3.08544e-08 (rank : 766)	NC score	0.288331 (rank : 1010)
Query Neighborhood Hits	2923	Target Neighborhood Hits	223	Shared Neighborhood Hits	217
SwissProt Accessions	Q9UQ72, Q13179, Q15242, Q9UNE4	Gene names	PSG11, PSG13
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 11 precursor (PSBG-11) (PSBG- 13).

ARBK1_HUMAN
θ value	4.0297e-08 (rank : 767)	NC score	0.697809 (rank : 333)
Query Neighborhood Hits	2923	Target Neighborhood Hits	859	Shared Neighborhood Hits	782
SwissProt Accessions	P25098, Q13837	Gene names	ADRBK1, BARK, BARK1, GRK2
Domain Architecture
Description	Beta-adrenergic receptor kinase 1 (EC 2.7.11.15) (Beta-ARK-1) (G- protein coupled receptor kinase 2).

ARBK1_MOUSE
θ value	4.0297e-08 (rank : 768)	NC score	0.696593 (rank : 339)
Query Neighborhood Hits	2923	Target Neighborhood Hits	849	Shared Neighborhood Hits	777
SwissProt Accessions	Q99MK8, Q99LL8	Gene names	Adrbk1, Grk2
Domain Architecture
Description	Beta-adrenergic receptor kinase 1 (EC 2.7.11.15) (Beta-ARK-1) (G- protein-coupled receptor kinase 2).

CXAR_MOUSE
θ value	4.0297e-08 (rank : 769)	NC score	0.265560 (rank : 1024)
Query Neighborhood Hits	2923	Target Neighborhood Hits	250	Shared Neighborhood Hits	223
SwissProt Accessions	P97792, O09052, Q3ULD0, Q91W66, Q99KG0, Q9DBJ8	Gene names	Cxadr, Car
Domain Architecture
Description	Coxsackievirus and adenovirus receptor homolog precursor (CAR) (mCAR).

EPHA6_MOUSE
θ value	4.0297e-08 (rank : 770)	NC score	0.545813 (rank : 767)
Query Neighborhood Hits	2923	Target Neighborhood Hits	946	Shared Neighborhood Hits	829
SwissProt Accessions	Q62413, Q8CCN2	Gene names	Epha6, Ehk-2, Ehk2
Domain Architecture
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

ITK_HUMAN
θ value	4.0297e-08 (rank : 771)	NC score	0.585958 (rank : 676)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1016	Shared Neighborhood Hits	791
SwissProt Accessions	Q08881	Gene names	ITK, EMT, LYK
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT).

PMYT1_MOUSE
θ value	4.0297e-08 (rank : 772)	NC score	0.694498 (rank : 352)
Query Neighborhood Hits	2923	Target Neighborhood Hits	910	Shared Neighborhood Hits	799
SwissProt Accessions	Q9ESG9, Q8R3L4	Gene names	Pkmyt1, Myt1
Domain Architecture	No domain graphic available
Description	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase).

EPHA2_MOUSE
θ value	5.26297e-08 (rank : 773)	NC score	0.587269 (rank : 672)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1020	Shared Neighborhood Hits	857
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

HCK_HUMAN
θ value	5.26297e-08 (rank : 774)	NC score	0.571807 (rank : 705)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1035	Shared Neighborhood Hits	796
SwissProt Accessions	P08631, Q5T7K1, Q5T7K2, Q96CC0, Q9H5Y5, Q9NUA4, Q9UMJ5	Gene names	HCK
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p59-HCK/p60-HCK) (Hemopoietic cell kinase).

MP2K4_HUMAN
θ value	5.26297e-08 (rank : 775)	NC score	0.683556 (rank : 440)
Query Neighborhood Hits	2923	Target Neighborhood Hits	832	Shared Neighborhood Hits	780
SwissProt Accessions	P45985, Q5U0B8	Gene names	MAP2K4, JNKK1, MKK4, PRKMK4, SERK1
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 4 (EC 2.7.12.2) (MAP kinase kinase 4) (JNK-activating kinase 1) (c-Jun N-terminal kinase kinase 1) (JNKK) (SAPK/ERK kinase 1) (SEK1).

MP2K4_MOUSE
θ value	5.26297e-08 (rank : 776)	NC score	0.683514 (rank : 441)
Query Neighborhood Hits	2923	Target Neighborhood Hits	833	Shared Neighborhood Hits	780
SwissProt Accessions	P47809	Gene names	Map2k4, Jnkk1, Prkmk4, Sek1, Serk1
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 4 (EC 2.7.12.2) (MAP kinase kinase 4) (MAPKK 4) (MAPK/ERK kinase 4) (JNK-activating kinase 1) (C-JUN N-terminal kinase kinase 1) (JNK kinase 1) (JNKK 1) (SAPK/ERK kinase 1) (SEK1).

PMYT1_HUMAN
θ value	5.26297e-08 (rank : 777)	NC score	0.690525 (rank : 393)
Query Neighborhood Hits	2923	Target Neighborhood Hits	814	Shared Neighborhood Hits	759
SwissProt Accessions	Q99640, O14731, Q7LE24, Q8TCM9	Gene names	PKMYT1, MYT1
Domain Architecture	No domain graphic available
Description	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase).

PSG3_HUMAN
θ value	5.26297e-08 (rank : 778)	NC score	0.299433 (rank : 1002)
Query Neighborhood Hits	2923	Target Neighborhood Hits	242	Shared Neighborhood Hits	231
SwissProt Accessions	Q16557, Q08265, Q9BRW2, Q9UPL4, Q9UQ77	Gene names	PSG3
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 3 precursor (PSBG-3) (Carcinoembryonic antigen SG5).

SON_MOUSE
θ value	5.26297e-08 (rank : 779)	NC score	0.089915 (rank : 1234)
Query Neighborhood Hits	2923	Target Neighborhood Hits	957	Shared Neighborhood Hits	377
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

STK16_MOUSE
θ value	5.26297e-08 (rank : 780)	NC score	0.688142 (rank : 412)
Query Neighborhood Hits	2923	Target Neighborhood Hits	824	Shared Neighborhood Hits	775
SwissProt Accessions	O88697, Q9JMJ0, Q9JMJ1, Q9QX00	Gene names	Stk16, Edpk, Krct, Mpsk1, Pkl12, Tsf1
Domain Architecture
Description	Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Protein kinase PKL12) (Myristoylated and palmitoylated serine/threonine-protein kinase) (MPSK) (TGF-beta-stimulated factor 1) (TSF-1) (Protein kinase Krct).

BASI_MOUSE
θ value	6.87365e-08 (rank : 781)	NC score	0.367418 (rank : 969)
Query Neighborhood Hits	2923	Target Neighborhood Hits	238	Shared Neighborhood Hits	225
SwissProt Accessions	P18572, Q6LDB0, Q7TSC0	Gene names	Bsg
Domain Architecture
Description	Basigin precursor (Basic immunoglobulin superfamily) (Membrane glycoprotein gp42) (HT7 antigen) (CD147 antigen).

BTK_MOUSE
θ value	6.87365e-08 (rank : 782)	NC score	0.584460 (rank : 681)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1017	Shared Neighborhood Hits	785
SwissProt Accessions	P35991, Q61365	Gene names	Btk, Bpk
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB).

GP116_HUMAN
θ value	6.87365e-08 (rank : 783)	NC score	0.073527 (rank : 1288)
Query Neighborhood Hits	2923	Target Neighborhood Hits	167	Shared Neighborhood Hits	89
SwissProt Accessions	Q8IZF2, O94858, Q6RGN2, Q86SP0, Q9Y3Z2	Gene names	GPR116, KIAA0758
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 116 precursor.

HCK_MOUSE
θ value	6.87365e-08 (rank : 784)	NC score	0.567577 (rank : 712)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1029	Shared Neighborhood Hits	795
SwissProt Accessions	P08103	Gene names	Hck
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK).

LAD1_HUMAN
θ value	6.87365e-08 (rank : 785)	NC score	0.099029 (rank : 1206)
Query Neighborhood Hits	2923	Target Neighborhood Hits	441	Shared Neighborhood Hits	218
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

MP2K6_HUMAN
θ value	6.87365e-08 (rank : 786)	NC score	0.674227 (rank : 480)
Query Neighborhood Hits	2923	Target Neighborhood Hits	830	Shared Neighborhood Hits	770
SwissProt Accessions	P52564	Gene names	MAP2K6, MEK6, MKK6, PRKMK6
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 6 (EC 2.7.12.2) (MAP kinase kinase 6) (MAPKK 6) (MAPK/ERK kinase 6) (SAPKK3).

MP2K6_MOUSE
θ value	6.87365e-08 (rank : 787)	NC score	0.675361 (rank : 473)
Query Neighborhood Hits	2923	Target Neighborhood Hits	830	Shared Neighborhood Hits	771
SwissProt Accessions	P70236	Gene names	Map2k6, Prkmk6, Sapkk3
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 6 (EC 2.7.12.2) (MAP kinase kinase 6) (MAPKK 6) (MAPK/ERK kinase 6) (SAPKK3).

STK16_HUMAN
θ value	6.87365e-08 (rank : 788)	NC score	0.690277 (rank : 398)
Query Neighborhood Hits	2923	Target Neighborhood Hits	824	Shared Neighborhood Hits	778
SwissProt Accessions	O75716, Q96KI2, Q9UEN3, Q9UP78	Gene names	STK16, MPSK1, PKL12, TSF1
Domain Architecture
Description	Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Protein kinase PKL12) (Myristoylated and palmitoylated serine/threonine-protein kinase) (MPSK) (TGF-beta-stimulated factor 1) (TSF-1) (hPSK).

ARAF_HUMAN
θ value	8.97725e-08 (rank : 789)	NC score	0.640431 (rank : 569)
Query Neighborhood Hits	2923	Target Neighborhood Hits	924	Shared Neighborhood Hits	794
SwissProt Accessions	P10398, P07557, Q5H9B3	Gene names	ARAF, ARAF1, PKS, PKS2
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (A- raf-1) (Proto-oncogene Pks).

ARAF_MOUSE
θ value	8.97725e-08 (rank : 790)	NC score	0.640425 (rank : 570)
Query Neighborhood Hits	2923	Target Neighborhood Hits	874	Shared Neighborhood Hits	781
SwissProt Accessions	P04627, Q99J44, Q9CTT5, Q9D6R6, Q9DBU7	Gene names	Araf, A-raf, Araf1
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1).

INSRR_HUMAN
θ value	8.97725e-08 (rank : 791)	NC score	0.551121 (rank : 755)
Query Neighborhood Hits	2923	Target Neighborhood Hits	950	Shared Neighborhood Hits	800
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

IRPL2_HUMAN
θ value	8.97725e-08 (rank : 792)	NC score	0.228633 (rank : 1051)
Query Neighborhood Hits	2923	Target Neighborhood Hits	194	Shared Neighborhood Hits	163
SwissProt Accessions	Q9NP60, Q9NZN0	Gene names	IL1RAPL2, IL1R9
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 2 precursor (IL1RAPL-2-related protein) (Interleukin-1 receptor 9) (IL-1R9) (IL-1 receptor accessory protein-like 2) (Three immunoglobulin domain- containing IL-1 receptor-related 1) (TIGIRR-1).

LRFN3_HUMAN
θ value	8.97725e-08 (rank : 793)	NC score	0.228739 (rank : 1050)
Query Neighborhood Hits	2923	Target Neighborhood Hits	444	Shared Neighborhood Hits	234
SwissProt Accessions	Q9BTN0, Q6UY10	Gene names	LRFN3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 3 precursor.

LRFN5_HUMAN
θ value	8.97725e-08 (rank : 794)	NC score	0.223303 (rank : 1057)
Query Neighborhood Hits	2923	Target Neighborhood Hits	464	Shared Neighborhood Hits	247
SwissProt Accessions	Q96NI6, Q86XL2	Gene names	LRFN5, C14orf146
Domain Architecture
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 5 precursor.

MALT1_HUMAN
θ value	8.97725e-08 (rank : 795)	NC score	0.426306 (rank : 915)
Query Neighborhood Hits	2923	Target Neighborhood Hits	236	Shared Neighborhood Hits	227
SwissProt Accessions	Q9UDY8, Q9NTB7, Q9ULX4	Gene names	MALT1, MLT
Domain Architecture
Description	Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (EC 3.4.22.-) (MALT lymphoma-associated translocation) (Paracaspase).

PECA1_MOUSE
θ value	8.97725e-08 (rank : 796)	NC score	0.218127 (rank : 1062)
Query Neighborhood Hits	2923	Target Neighborhood Hits	126	Shared Neighborhood Hits	121
SwissProt Accessions	Q08481	Gene names	Pecam1, Pecam, Pecam-1
Domain Architecture
Description	Platelet endothelial cell adhesion molecule precursor (PECAM-1) (CD31 antigen).

SORL_HUMAN
θ value	8.97725e-08 (rank : 797)	NC score	0.139053 (rank : 1150)
Query Neighborhood Hits	2923	Target Neighborhood Hits	440	Shared Neighborhood Hits	165
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

SORL_MOUSE
θ value	8.97725e-08 (rank : 798)	NC score	0.136217 (rank : 1153)
Query Neighborhood Hits	2923	Target Neighborhood Hits	439	Shared Neighborhood Hits	167
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

VSIG2_HUMAN
θ value	8.97725e-08 (rank : 799)	NC score	0.383040 (rank : 957)
Query Neighborhood Hits	2923	Target Neighborhood Hits	321	Shared Neighborhood Hits	282
SwissProt Accessions	Q96IQ7, O95791, Q9NX42	Gene names	VSIG2, CTH, CTXL
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 2 precursor (CT- like protein) (Cortical thymocyte-like protein).

CD2L2_HUMAN
θ value	1.17247e-07 (rank : 800)	NC score	0.675473 (rank : 470)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1439	Shared Neighborhood Hits	1056
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

CD2L6_HUMAN
θ value	1.17247e-07 (rank : 801)	NC score	0.668838 (rank : 498)
Query Neighborhood Hits	2923	Target Neighborhood Hits	844	Shared Neighborhood Hits	777
SwissProt Accessions	Q9BWU1, Q5JQZ7, Q5JR00, Q8TC78, Q9UPX2	Gene names	CDC2L6, CDK11, KIAA1028
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 6 (EC 2.7.11.22) (CDC2- related protein kinase 6) (Death-preventing kinase) (Cyclin-dependent kinase 11).

CD2L6_MOUSE
θ value	1.17247e-07 (rank : 802)	NC score	0.668954 (rank : 496)
Query Neighborhood Hits	2923	Target Neighborhood Hits	851	Shared Neighborhood Hits	780
SwissProt Accessions	Q8BWD8, Q80TM1	Gene names	Cdc2l6, Kiaa1028
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 6 (EC 2.7.11.22) (CDC2- related protein kinase 6).

CSF1R_HUMAN
θ value	1.17247e-07 (rank : 803)	NC score	0.564431 (rank : 717)
Query Neighborhood Hits	2923	Target Neighborhood Hits	943	Shared Neighborhood Hits	878
SwissProt Accessions	P07333, Q6LDW5, Q6LDY4	Gene names	CSF1R, FMS
Domain Architecture
Description	Macrophage colony-stimulating factor 1 receptor precursor (EC 2.7.10.1) (CSF-1-R) (Fms proto-oncogene) (c-fms) (CD115 antigen).

FGR_HUMAN
θ value	1.17247e-07 (rank : 804)	NC score	0.558094 (rank : 727)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1067	Shared Neighborhood Hits	801
SwissProt Accessions	P09769, Q9UIQ3	Gene names	FGR, SRC2
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

INSR_HUMAN
θ value	1.17247e-07 (rank : 805)	NC score	0.566132 (rank : 714)
Query Neighborhood Hits	2923	Target Neighborhood Hits	963	Shared Neighborhood Hits	816
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

ITK_MOUSE
θ value	1.17247e-07 (rank : 806)	NC score	0.585958 (rank : 675)
Query Neighborhood Hits	2923	Target Neighborhood Hits	985	Shared Neighborhood Hits	782
SwissProt Accessions	Q03526	Gene names	Itk, Emt, Tlk, Tsk
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK).

KSR1_MOUSE
θ value	1.17247e-07 (rank : 807)	NC score	0.606130 (rank : 623)
Query Neighborhood Hits	2923	Target Neighborhood Hits	870	Shared Neighborhood Hits	769
SwissProt Accessions	Q61097, Q61648, Q78DX8	Gene names	Ksr1, Ksr
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras) (mKSR1) (Hb protein).

LYN_HUMAN
θ value	1.17247e-07 (rank : 808)	NC score	0.582622 (rank : 686)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1022	Shared Neighborhood Hits	797
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

M3K14_MOUSE
θ value	1.17247e-07 (rank : 809)	NC score	0.699765 (rank : 319)
Query Neighborhood Hits	2923	Target Neighborhood Hits	889	Shared Neighborhood Hits	792
SwissProt Accessions	Q9WUL6	Gene names	Map3k14, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF- kappa beta-inducing kinase) (Serine/threonine-protein kinase NIK).

MATK_HUMAN
θ value	1.17247e-07 (rank : 810)	NC score	0.582091 (rank : 688)
Query Neighborhood Hits	2923	Target Neighborhood Hits	954	Shared Neighborhood Hits	777
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

PTPRM_HUMAN
θ value	1.17247e-07 (rank : 811)	NC score	0.185969 (rank : 1098)
Query Neighborhood Hits	2923	Target Neighborhood Hits	244	Shared Neighborhood Hits	178
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

TRIB3_HUMAN
θ value	1.17247e-07 (rank : 812)	NC score	0.620650 (rank : 598)
Query Neighborhood Hits	2923	Target Neighborhood Hits	519	Shared Neighborhood Hits	509
SwissProt Accessions	Q96RU7, Q53GU4, Q53ZW7, Q6I9Y9, Q8TAI6, Q9H5M8, Q9NUD2	Gene names	TRIB3, C20orf97, NIPK, SKIP3, TRB3
Domain Architecture
Description	Tribbles homolog 3 (TRB-3) (Neuronal cell death-inducible putative kinase) (p65-interacting inhibitor of NF-kappaB) (SINK).

TYK2_MOUSE
θ value	1.17247e-07 (rank : 813)	NC score	0.614866 (rank : 607)
Query Neighborhood Hits	2923	Target Neighborhood Hits	850	Shared Neighborhood Hits	783
SwissProt Accessions	Q9R117, O88431, Q8VE41	Gene names	Tyk2
Domain Architecture
Description	Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2).

CD2L1_HUMAN
θ value	1.53129e-07 (rank : 814)	NC score	0.674472 (rank : 478)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1467	Shared Neighborhood Hits	1054
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

CD2L1_MOUSE
θ value	1.53129e-07 (rank : 815)	NC score	0.674546 (rank : 477)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1463	Shared Neighborhood Hits	1052
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

CDK4_MOUSE
θ value	1.53129e-07 (rank : 816)	NC score	0.685346 (rank : 426)
Query Neighborhood Hits	2923	Target Neighborhood Hits	838	Shared Neighborhood Hits	781
SwissProt Accessions	P30285	Gene names	Cdk4, Crk3
Domain Architecture
Description	Cell division protein kinase 4 (EC 2.7.11.22) (Cyclin-dependent kinase 4) (PSK-J3) (CRK3).

CDK8_HUMAN
θ value	1.53129e-07 (rank : 817)	NC score	0.666611 (rank : 508)
Query Neighborhood Hits	2923	Target Neighborhood Hits	831	Shared Neighborhood Hits	774
SwissProt Accessions	P49336	Gene names	CDK8
Domain Architecture
Description	Cell division protein kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Protein kinase K35).

FRK_HUMAN
θ value	1.53129e-07 (rank : 818)	NC score	0.583428 (rank : 684)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1058	Shared Neighborhood Hits	796
SwissProt Accessions	P42685, Q13128	Gene names	FRK
Domain Architecture
Description	Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear tyrosine protein kinase RAK).

LTK_HUMAN
θ value	1.53129e-07 (rank : 819)	NC score	0.518358 (rank : 821)
Query Neighborhood Hits	2923	Target Neighborhood Hits	774	Shared Neighborhood Hits	709
SwissProt Accessions	P29376	Gene names	LTK, TYK1
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1) (Protein tyrosine kinase 1).

LTK_MOUSE
θ value	1.53129e-07 (rank : 820)	NC score	0.524312 (rank : 807)
Query Neighborhood Hits	2923	Target Neighborhood Hits	770	Shared Neighborhood Hits	701
SwissProt Accessions	P08923	Gene names	Ltk
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1).

MP2K2_HUMAN
θ value	1.53129e-07 (rank : 821)	NC score	0.691876 (rank : 379)
Query Neighborhood Hits	2923	Target Neighborhood Hits	830	Shared Neighborhood Hits	776
SwissProt Accessions	P36507	Gene names	MAP2K2, MEK2, MKK2, PRKMK2
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 2 (EC 2.7.12.2) (MAP kinase kinase 2) (MAPKK 2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK2).

RAGE_MOUSE
θ value	1.53129e-07 (rank : 822)	NC score	0.408865 (rank : 939)
Query Neighborhood Hits	2923	Target Neighborhood Hits	295	Shared Neighborhood Hits	243
SwissProt Accessions	Q62151	Gene names	Ager, Rage
Domain Architecture
Description	Advanced glycosylation end product-specific receptor precursor (Receptor for advanced glycosylation end products).

TEC_HUMAN
θ value	1.53129e-07 (rank : 823)	NC score	0.591282 (rank : 657)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1006	Shared Neighborhood Hits	784
SwissProt Accessions	P42680	Gene names	TEC, PSCTK4
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

ABL1_HUMAN
θ value	1.99992e-07 (rank : 824)	NC score	0.588375 (rank : 669)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1220	Shared Neighborhood Hits	860
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

INSRR_MOUSE
θ value	1.99992e-07 (rank : 825)	NC score	0.554380 (rank : 746)
Query Neighborhood Hits	2923	Target Neighborhood Hits	961	Shared Neighborhood Hits	801
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

TEC_MOUSE
θ value	1.99992e-07 (rank : 826)	NC score	0.595828 (rank : 647)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1006	Shared Neighborhood Hits	787
SwissProt Accessions	P24604, Q9R1M9, Q9WVN0, Q9WVN1, Q9WVN2, Q9WVN3	Gene names	Tec
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

VSIG4_HUMAN
θ value	1.99992e-07 (rank : 827)	NC score	0.355892 (rank : 972)
Query Neighborhood Hits	2923	Target Neighborhood Hits	236	Shared Neighborhood Hits	230
SwissProt Accessions	Q9Y279, Q6UXI4	Gene names	VSIG4, Z39IG
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 4 precursor (Protein Z39Ig).

ABL1_MOUSE
θ value	2.61198e-07 (rank : 828)	NC score	0.590323 (rank : 662)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1178	Shared Neighborhood Hits	869
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

CDK4_HUMAN
θ value	2.61198e-07 (rank : 829)	NC score	0.684398 (rank : 433)
Query Neighborhood Hits	2923	Target Neighborhood Hits	834	Shared Neighborhood Hits	779
SwissProt Accessions	P11802, O00576	Gene names	CDK4
Domain Architecture
Description	Cell division protein kinase 4 (EC 2.7.11.22) (Cyclin-dependent kinase 4) (PSK-J3).

IRAK4_HUMAN
θ value	2.61198e-07 (rank : 830)	NC score	0.643727 (rank : 563)
Query Neighborhood Hits	2923	Target Neighborhood Hits	816	Shared Neighborhood Hits	759
SwissProt Accessions	Q9NWZ3, Q8TDF7, Q9Y589	Gene names	IRAK4
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1) (IRAK-4) (NY- REN-64 antigen).

LRFN2_MOUSE
θ value	2.61198e-07 (rank : 831)	NC score	0.241787 (rank : 1037)
Query Neighborhood Hits	2923	Target Neighborhood Hits	450	Shared Neighborhood Hits	246
SwissProt Accessions	Q80TG9, Q9CYK3	Gene names	Lrfn2, Kiaa1246
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 2 precursor.

M3K11_HUMAN
θ value	2.61198e-07 (rank : 832)	NC score	0.646568 (rank : 556)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1136	Shared Neighborhood Hits	877
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

M3K12_HUMAN
θ value	2.61198e-07 (rank : 833)	NC score	0.660953 (rank : 524)
Query Neighborhood Hits	2923	Target Neighborhood Hits	940	Shared Neighborhood Hits	820
SwissProt Accessions	Q12852, Q86VQ5, Q8WY25	Gene names	MAP3K12, ZPK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

M3K12_MOUSE
θ value	2.61198e-07 (rank : 834)	NC score	0.660675 (rank : 525)
Query Neighborhood Hits	2923	Target Neighborhood Hits	957	Shared Neighborhood Hits	820
SwissProt Accessions	Q60700, P70286, Q3TLL7, Q8C4N7, Q8CBX3, Q8CDL6	Gene names	Map3k12, Zpk
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

M3K14_HUMAN
θ value	2.61198e-07 (rank : 835)	NC score	0.704163 (rank : 292)
Query Neighborhood Hits	2923	Target Neighborhood Hits	887	Shared Neighborhood Hits	807
SwissProt Accessions	Q99558, Q8IYN1	Gene names	MAP3K14, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF- kappa beta-inducing kinase) (Serine/threonine-protein kinase NIK) (HsNIK).

NRG2_MOUSE
θ value	2.61198e-07 (rank : 836)	NC score	0.335392 (rank : 987)
Query Neighborhood Hits	2923	Target Neighborhood Hits	392	Shared Neighborhood Hits	269
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

PCLO_HUMAN
θ value	2.61198e-07 (rank : 837)	NC score	0.096692 (rank : 1215)
Query Neighborhood Hits	2923	Target Neighborhood Hits	2046	Shared Neighborhood Hits	766
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

TIE1_HUMAN
θ value	2.61198e-07 (rank : 838)	NC score	0.614546 (rank : 608)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1241	Shared Neighborhood Hits	930
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

WEE1_MOUSE
θ value	2.61198e-07 (rank : 839)	NC score	0.665697 (rank : 511)
Query Neighborhood Hits	2923	Target Neighborhood Hits	794	Shared Neighborhood Hits	739
SwissProt Accessions	P47810, Q9EPL7	Gene names	Wee1
Domain Architecture
Description	Wee1-like protein kinase (EC 2.7.10.2) (Wee1A kinase).

CD166_HUMAN
θ value	3.41135e-07 (rank : 840)	NC score	0.331352 (rank : 988)
Query Neighborhood Hits	2923	Target Neighborhood Hits	247	Shared Neighborhood Hits	229
SwissProt Accessions	Q13740, O60892	Gene names	ALCAM, MEMD
Domain Architecture
Description	CD166 antigen precursor (Activated leukocyte-cell adhesion molecule) (ALCAM).

CSK_HUMAN
θ value	3.41135e-07 (rank : 841)	NC score	0.585543 (rank : 677)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1009	Shared Neighborhood Hits	787
SwissProt Accessions	P41240, Q6FGZ6	Gene names	CSK
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase CYL).

IRPL2_MOUSE
θ value	3.41135e-07 (rank : 842)	NC score	0.225322 (rank : 1054)
Query Neighborhood Hits	2923	Target Neighborhood Hits	195	Shared Neighborhood Hits	162
SwissProt Accessions	Q9ERS6, Q9ER66	Gene names	Il1rapl2
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 2 precursor (IL1RAPL-2-related protein) (TIGIRR-1).

M3K9_HUMAN
θ value	3.41135e-07 (rank : 843)	NC score	0.645886 (rank : 558)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1123	Shared Neighborhood Hits	867
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

NRG2_HUMAN
θ value	3.41135e-07 (rank : 844)	NC score	0.342490 (rank : 984)
Query Neighborhood Hits	2923	Target Neighborhood Hits	419	Shared Neighborhood Hits	287
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

PGFRL_HUMAN
θ value	3.41135e-07 (rank : 845)	NC score	0.217084 (rank : 1063)
Query Neighborhood Hits	2923	Target Neighborhood Hits	115	Shared Neighborhood Hits	113
SwissProt Accessions	Q15198, Q6FH04	Gene names	PDGFRL, PRLTS
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor receptor-like protein precursor (PDGF receptor beta-like tumor suppressor).

TMIGD_MOUSE
θ value	3.41135e-07 (rank : 846)	NC score	0.415810 (rank : 926)
Query Neighborhood Hits	2923	Target Neighborhood Hits	234	Shared Neighborhood Hits	233
SwissProt Accessions	Q9D7L8, Q8R202	Gene names	Tmigd
Domain Architecture	No domain graphic available
Description	Transmembrane and immunoglobulin domain-containing protein precursor.

AAK1_MOUSE
θ value	4.45536e-07 (rank : 847)	NC score	0.665291 (rank : 513)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1051	Shared Neighborhood Hits	872
SwissProt Accessions	Q3UHJ0, Q3TY53, Q6ZPZ6, Q80XP6	Gene names	Aak1, Kiaa1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

ACK1_MOUSE
θ value	4.45536e-07 (rank : 848)	NC score	0.571035 (rank : 708)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1080	Shared Neighborhood Hits	868
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

FLT3_HUMAN
θ value	4.45536e-07 (rank : 849)	NC score	0.536975 (rank : 789)
Query Neighborhood Hits	2923	Target Neighborhood Hits	843	Shared Neighborhood Hits	785
SwissProt Accessions	P36888, Q13414	Gene names	FLT3, STK1
Domain Architecture
Description	FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor FLT3) (Stem cell tyrosine kinase 1) (STK-1) (CD135 antigen).

LRRK1_MOUSE
θ value	4.45536e-07 (rank : 850)	NC score	0.608595 (rank : 618)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1267	Shared Neighborhood Hits	824
SwissProt Accessions	Q3UHC2, Q3U476, Q66JQ4, Q6GQR9, Q6NZF5, Q6ZPI4, Q8BKP3, Q8BU93, Q8BUY0, Q8BVV2, Q8R085	Gene names	Lrrk1, Kiaa1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

MATK_MOUSE
θ value	4.45536e-07 (rank : 851)	NC score	0.585105 (rank : 679)
Query Neighborhood Hits	2923	Target Neighborhood Hits	952	Shared Neighborhood Hits	780
SwissProt Accessions	P41242, Q6LE90	Gene names	Matk, Ctk, Ntk
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK).

NRK_MOUSE
θ value	4.45536e-07 (rank : 852)	NC score	0.680405 (rank : 459)
Query Neighborhood Hits	2923	Target Neighborhood Hits	899	Shared Neighborhood Hits	813
SwissProt Accessions	Q9R0G8, Q6NV55, Q8C9S9, Q9R0S4	Gene names	Nrk, Nesk
Domain Architecture	No domain graphic available
Description	Nik-related protein kinase (EC 2.7.11.1) (Nck-interacting kinase-like embryo specific kinase) (NIK-like embryo-specific kinase) (NESK).

TIE2_MOUSE
θ value	4.45536e-07 (rank : 853)	NC score	0.624526 (rank : 592)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1204	Shared Neighborhood Hits	905
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

AAK1_HUMAN
θ value	5.81887e-07 (rank : 854)	NC score	0.666534 (rank : 509)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1077	Shared Neighborhood Hits	882
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

IL1R1_HUMAN
θ value	5.81887e-07 (rank : 855)	NC score	0.197708 (rank : 1084)
Query Neighborhood Hits	2923	Target Neighborhood Hits	140	Shared Neighborhood Hits	132
SwissProt Accessions	P14778	Gene names	IL1R1, IL1R, IL1RA, IL1RT1
Domain Architecture
Description	Interleukin-1 receptor type I precursor (IL-1R-1) (IL-1RT1) (IL-1R- alpha) (p80) (CD121a antigen).

ILRL2_MOUSE
θ value	5.81887e-07 (rank : 856)	NC score	0.193958 (rank : 1089)
Query Neighborhood Hits	2923	Target Neighborhood Hits	158	Shared Neighborhood Hits	152
SwissProt Accessions	Q9ERS7	Gene names	Il1rl2
Domain Architecture
Description	Interleukin-1 receptor-like 2 precursor (IL-1Rrp2).

INSR_MOUSE
θ value	5.81887e-07 (rank : 857)	NC score	0.566400 (rank : 713)
Query Neighborhood Hits	2923	Target Neighborhood Hits	968	Shared Neighborhood Hits	817
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

LRFN2_HUMAN
θ value	5.81887e-07 (rank : 858)	NC score	0.241761 (rank : 1038)
Query Neighborhood Hits	2923	Target Neighborhood Hits	450	Shared Neighborhood Hits	243
SwissProt Accessions	Q9ULH4, Q5SYP9	Gene names	LRFN2, KIAA1246
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 2 precursor.

LRFN4_HUMAN
θ value	5.81887e-07 (rank : 859)	NC score	0.247310 (rank : 1033)
Query Neighborhood Hits	2923	Target Neighborhood Hits	462	Shared Neighborhood Hits	252
SwissProt Accessions	Q6PJG9, Q9BWJ0	Gene names	LRFN4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursor.

M3K10_HUMAN
θ value	5.81887e-07 (rank : 860)	NC score	0.644406 (rank : 562)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1071	Shared Neighborhood Hits	851
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

SIG12_HUMAN
θ value	5.81887e-07 (rank : 861)	NC score	0.257065 (rank : 1029)
Query Neighborhood Hits	2923	Target Neighborhood Hits	245	Shared Neighborhood Hits	233
SwissProt Accessions	Q96PQ1, Q8IYH7	Gene names	SIGLEC12, SIGLECL1, SLG
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 12 precursor (Siglec-12) (Sialic acid-binding Ig-like lectin-like 1) (Siglec-L1).

TNK1_MOUSE
θ value	5.81887e-07 (rank : 862)	NC score	0.582604 (rank : 687)
Query Neighborhood Hits	2923	Target Neighborhood Hits	806	Shared Neighborhood Hits	737
SwissProt Accessions	Q99ML2, Q8CCC4, Q8K0X9, Q91V11	Gene names	Tnk1, Kos1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (Kinase of embryonic stem cells).

WEE1_HUMAN
θ value	5.81887e-07 (rank : 863)	NC score	0.655538 (rank : 535)
Query Neighborhood Hits	2923	Target Neighborhood Hits	777	Shared Neighborhood Hits	725
SwissProt Accessions	P30291	Gene names	WEE1
Domain Architecture
Description	Wee1-like protein kinase (EC 2.7.10.2) (Wee1A kinase) (WEE1hu).

ALK_MOUSE
θ value	7.59969e-07 (rank : 864)	NC score	0.522881 (rank : 814)
Query Neighborhood Hits	2923	Target Neighborhood Hits	811	Shared Neighborhood Hits	712
SwissProt Accessions	P97793	Gene names	Alk
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

FA47B_HUMAN
θ value	7.59969e-07 (rank : 865)	NC score	0.061484 (rank : 1401)
Query Neighborhood Hits	2923	Target Neighborhood Hits	431	Shared Neighborhood Hits	164
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

GAK_MOUSE
θ value	7.59969e-07 (rank : 866)	NC score	0.661503 (rank : 522)
Query Neighborhood Hits	2923	Target Neighborhood Hits	964	Shared Neighborhood Hits	802
SwissProt Accessions	Q99KY4, Q6P1I8, Q6P9S5, Q8BM74, Q8K0Q4	Gene names	Gak
Domain Architecture	No domain graphic available
Description	Cyclin G-associated kinase (EC 2.7.11.1).

IGF1R_HUMAN
θ value	7.59969e-07 (rank : 867)	NC score	0.550165 (rank : 756)
Query Neighborhood Hits	2923	Target Neighborhood Hits	977	Shared Neighborhood Hits	806
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

KSR1_HUMAN
θ value	7.59969e-07 (rank : 868)	NC score	0.597551 (rank : 644)
Query Neighborhood Hits	2923	Target Neighborhood Hits	867	Shared Neighborhood Hits	755
SwissProt Accessions	Q8IVT5, Q13476	Gene names	KSR1, KSR
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras).

LRRC4_HUMAN
θ value	7.59969e-07 (rank : 869)	NC score	0.144698 (rank : 1143)
Query Neighborhood Hits	2923	Target Neighborhood Hits	444	Shared Neighborhood Hits	225
SwissProt Accessions	Q9HBW1, Q6ZMI8, Q96A85	Gene names	LRRC4, BAG
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4 precursor (Brain tumor- associated protein LRRC4) (NAG14).

MP2K2_MOUSE
θ value	7.59969e-07 (rank : 870)	NC score	0.689685 (rank : 402)
Query Neighborhood Hits	2923	Target Neighborhood Hits	828	Shared Neighborhood Hits	775
SwissProt Accessions	Q63932	Gene names	Map2k2, Mek2, Mkk2, Prkmk2
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 2 (EC 2.7.12.2) (MAP kinase kinase 2) (MAPKK 2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK2).

NFM_HUMAN
θ value	7.59969e-07 (rank : 871)	NC score	0.052249 (rank : 1656)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1328	Shared Neighborhood Hits	573
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

PVRL3_MOUSE
θ value	7.59969e-07 (rank : 872)	NC score	0.248198 (rank : 1032)
Query Neighborhood Hits	2923	Target Neighborhood Hits	212	Shared Neighborhood Hits	203
SwissProt Accessions	Q9JLB9, Q9D006, Q9JLB7, Q9JLB8	Gene names	Pvrl3
Domain Architecture	No domain graphic available
Description	Poliovirus receptor-related protein 3 precursor (Cell adhesion molecule nectin-3) (Nectin-3) (CDw113 antigen).

ACK1_HUMAN
θ value	9.92553e-07 (rank : 873)	NC score	0.573137 (rank : 701)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1140	Shared Neighborhood Hits	896
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

CDK9_HUMAN
θ value	9.92553e-07 (rank : 874)	NC score	0.674678 (rank : 475)
Query Neighborhood Hits	2923	Target Neighborhood Hits	822	Shared Neighborhood Hits	766
SwissProt Accessions	P50750, Q5JU24, Q5JU25, Q5U006, Q96TF1	Gene names	CDK9, CDC2L4
Domain Architecture
Description	Cell division protein kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (Cyclin- dependent kinase 9) (Serine/threonine-protein kinase PITALRE) (C-2K) (Cell division cycle 2-like protein kinase 4).

E2AK2_MOUSE
θ value	9.92553e-07 (rank : 875)	NC score	0.702833 (rank : 301)
Query Neighborhood Hits	2923	Target Neighborhood Hits	864	Shared Neighborhood Hits	784
SwissProt Accessions	Q03963, Q61742, Q62026	Gene names	Eif2ak2, Pkr, Prkr, Tik
Domain Architecture
Description	Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Interferon-inducible RNA-dependent protein kinase) (Protein kinase RNA-activated) (PKR) (p68 kinase) (P1/eIF-2A protein kinase) (Serine/threonine-protein kinase TIK).

GAK_HUMAN
θ value	9.92553e-07 (rank : 876)	NC score	0.664050 (rank : 516)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1028	Shared Neighborhood Hits	830
SwissProt Accessions	O14976, Q9BVY6	Gene names	GAK
Domain Architecture
Description	Cyclin G-associated kinase (EC 2.7.11.1).

MP2K1_HUMAN
θ value	9.92553e-07 (rank : 877)	NC score	0.690922 (rank : 388)
Query Neighborhood Hits	2923	Target Neighborhood Hits	826	Shared Neighborhood Hits	776
SwissProt Accessions	Q02750	Gene names	MAP2K1, MEK1, PRKMK1
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 1 (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1).

MP2K1_MOUSE
θ value	9.92553e-07 (rank : 878)	NC score	0.690780 (rank : 391)
Query Neighborhood Hits	2923	Target Neighborhood Hits	826	Shared Neighborhood Hits	776
SwissProt Accessions	P31938	Gene names	Map2k1, Mek1, Prkmk1
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 1 (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1).

NRG1_HUMAN
θ value	9.92553e-07 (rank : 879)	NC score	0.263713 (rank : 1025)
Query Neighborhood Hits	2923	Target Neighborhood Hits	285	Shared Neighborhood Hits	199
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

TRIB3_MOUSE
θ value	9.92553e-07 (rank : 880)	NC score	0.636330 (rank : 580)
Query Neighborhood Hits	2923	Target Neighborhood Hits	578	Shared Neighborhood Hits	566
SwissProt Accessions	Q8K4K2, Q3UMQ0, Q921E7	Gene names	Trib3, Nipk, Trb3
Domain Architecture
Description	Tribbles homolog 3 (TRB-3) (Neuronal cell death-inducible putative kinase).

ALK_HUMAN
θ value	1.29631e-06 (rank : 881)	NC score	0.524131 (rank : 809)
Query Neighborhood Hits	2923	Target Neighborhood Hits	795	Shared Neighborhood Hits	698
SwissProt Accessions	Q9UM73, Q9Y4K6	Gene names	ALK
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

BLK_MOUSE
θ value	1.29631e-06 (rank : 882)	NC score	0.571426 (rank : 707)
Query Neighborhood Hits	2923	Target Neighborhood Hits	992	Shared Neighborhood Hits	780
SwissProt Accessions	P16277	Gene names	Blk
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

EPHAA_HUMAN
θ value	1.29631e-06 (rank : 883)	NC score	0.498063 (rank : 843)
Query Neighborhood Hits	2923	Target Neighborhood Hits	960	Shared Neighborhood Hits	770
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

ERN1_MOUSE
θ value	1.29631e-06 (rank : 884)	NC score	0.680441 (rank : 458)
Query Neighborhood Hits	2923	Target Neighborhood Hits	823	Shared Neighborhood Hits	766
SwissProt Accessions	Q9EQY0, Q9D340	Gene names	Ern1, Ire1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase/endoribonuclease IRE1 precursor (Inositol-requiring protein 1) (IRE1a) (Ire1-alpha) (Endoplasmic reticulum-to-nucleus signaling 1) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)].

IGF1R_MOUSE
θ value	1.29631e-06 (rank : 885)	NC score	0.551284 (rank : 754)
Query Neighborhood Hits	2923	Target Neighborhood Hits	973	Shared Neighborhood Hits	810
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

IRAK4_MOUSE
θ value	1.29631e-06 (rank : 886)	NC score	0.648210 (rank : 553)
Query Neighborhood Hits	2923	Target Neighborhood Hits	820	Shared Neighborhood Hits	757
SwissProt Accessions	Q8R4K2, Q80WW1	Gene names	Irak4
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1) (IRAK-4).

LRRK1_HUMAN
θ value	1.29631e-06 (rank : 887)	NC score	0.610963 (rank : 615)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1237	Shared Neighborhood Hits	819
SwissProt Accessions	Q38SD2, Q6NVH5, Q6NYC0, Q6ZNL9, Q6ZNM9, Q96JN5, Q9H5S3	Gene names	LRRK1, KIAA1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

MP2K3_MOUSE
θ value	1.29631e-06 (rank : 888)	NC score	0.678820 (rank : 463)
Query Neighborhood Hits	2923	Target Neighborhood Hits	826	Shared Neighborhood Hits	770
SwissProt Accessions	O09110, P97293, Q91VX1	Gene names	Map2k3, Mkk3, Prkmk3
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 3 (EC 2.7.12.2) (MAP kinase kinase 3) (MAPKK 3) (MAPK/ERK kinase 3).

OGFR_MOUSE
θ value	1.29631e-06 (rank : 889)	NC score	0.055951 (rank : 1558)
Query Neighborhood Hits	2923	Target Neighborhood Hits	584	Shared Neighborhood Hits	208
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

FCG2A_HUMAN
θ value	1.69304e-06 (rank : 890)	NC score	0.139510 (rank : 1149)
Query Neighborhood Hits	2923	Target Neighborhood Hits	92	Shared Neighborhood Hits	88
SwissProt Accessions	P12318	Gene names	FCGR2A, CD32, FCG2, IGFR2
Domain Architecture
Description	Low affinity immunoglobulin gamma Fc region receptor II-a precursor (Fc-gamma RII-a) (FcRII-a) (IgG Fc receptor II-a) (Fc-gamma-RIIa) (CD32 antigen) (CDw32).

I12R2_HUMAN
θ value	1.69304e-06 (rank : 891)	NC score	0.203503 (rank : 1076)
Query Neighborhood Hits	2923	Target Neighborhood Hits	163	Shared Neighborhood Hits	134
SwissProt Accessions	Q99665	Gene names	IL12RB2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

PVRL3_HUMAN
θ value	1.69304e-06 (rank : 892)	NC score	0.240939 (rank : 1040)
Query Neighborhood Hits	2923	Target Neighborhood Hits	204	Shared Neighborhood Hits	193
SwissProt Accessions	Q9NQS3, Q6NVZ3, Q8WVU4, Q9BVA9, Q9Y412	Gene names	PVRL3, PRR3
Domain Architecture	No domain graphic available
Description	Poliovirus receptor-related protein 3 precursor (Nectin-3) (CDw113 antigen).

TMIGD_HUMAN
θ value	1.69304e-06 (rank : 893)	NC score	0.433359 (rank : 903)
Query Neighborhood Hits	2923	Target Neighborhood Hits	240	Shared Neighborhood Hits	234
SwissProt Accessions	Q6UXZ0, Q6ZMC6	Gene names	TMIGD
Domain Architecture	No domain graphic available
Description	Transmembrane and immunoglobulin domain-containing protein precursor.

LIMK1_HUMAN
θ value	2.21117e-06 (rank : 894)	NC score	0.627971 (rank : 587)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1005	Shared Neighborhood Hits	791
SwissProt Accessions	P53667, O15283, Q15820, Q15821, Q75MU3, Q9Y5Q1	Gene names	LIMK1, LIMK
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1).

NGL1_HUMAN
θ value	2.21117e-06 (rank : 895)	NC score	0.164808 (rank : 1119)
Query Neighborhood Hits	2923	Target Neighborhood Hits	511	Shared Neighborhood Hits	273
SwissProt Accessions	Q9HCJ2, Q7L0N3	Gene names	LRRC4C, KIAA1580, NGL1
Domain Architecture	No domain graphic available
Description	Netrin-G1 ligand precursor (NGL-1) (Leucine-rich repeat-containing protein 4C).

NGL1_MOUSE
θ value	2.21117e-06 (rank : 896)	NC score	0.165038 (rank : 1117)
Query Neighborhood Hits	2923	Target Neighborhood Hits	512	Shared Neighborhood Hits	274
SwissProt Accessions	Q8C031, Q8BGH8	Gene names	Lrrc4c, Ngl1
Domain Architecture	No domain graphic available
Description	Netrin-G1 ligand precursor (NGL-1) (Leucine-rich repeat-containing protein 4C).

ABL2_HUMAN
θ value	2.88788e-06 (rank : 897)	NC score	0.584133 (rank : 682)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1045	Shared Neighborhood Hits	797
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

EMB_HUMAN
θ value	2.88788e-06 (rank : 898)	NC score	0.143723 (rank : 1145)
Query Neighborhood Hits	2923	Target Neighborhood Hits	54	Shared Neighborhood Hits	49
SwissProt Accessions	Q6PCB8	Gene names	EMB
Domain Architecture	No domain graphic available
Description	Embigin precursor.

FCG2B_HUMAN
θ value	2.88788e-06 (rank : 899)	NC score	0.154460 (rank : 1132)
Query Neighborhood Hits	2923	Target Neighborhood Hits	116	Shared Neighborhood Hits	102
SwissProt Accessions	P31994, O95649, Q53X85, Q5VXA9, Q8NIA1	Gene names	FCGR2B, CD32, FCG2, IGFR2
Domain Architecture
Description	Low affinity immunoglobulin gamma Fc region receptor II-b precursor (Fc-gamma RII-b) (FcRII-b) (IgG Fc receptor II-b) (Fc-gamma-RIIb) (CD32 antigen) (CDw32).

FCG2C_HUMAN
θ value	2.88788e-06 (rank : 900)	NC score	0.153735 (rank : 1134)
Query Neighborhood Hits	2923	Target Neighborhood Hits	118	Shared Neighborhood Hits	103
SwissProt Accessions	P31995, O00523, O00524, O00525	Gene names	FCGR2C, CD32, FCG2, IGFR2
Domain Architecture
Description	Low affinity immunoglobulin gamma Fc region receptor II-c precursor (Fc-gamma RII-c) (FcRII-c) (IgG Fc receptor II-c) (Fc-gamma-RIIc) (CD32 antigen) (CDw32).

SPR1B_MOUSE
θ value	2.88788e-06 (rank : 901)	NC score	0.058167 (rank : 1489)
Query Neighborhood Hits	2923	Target Neighborhood Hits	395	Shared Neighborhood Hits	130
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

UHMK1_HUMAN
θ value	2.88788e-06 (rank : 902)	NC score	0.675376 (rank : 472)
Query Neighborhood Hits	2923	Target Neighborhood Hits	808	Shared Neighborhood Hits	746
SwissProt Accessions	Q8TAS1, Q96C22	Gene names	UHMK1, KIS, KIST
Domain Architecture
Description	Serine/threonine-protein kinase Kist (EC 2.7.11.1) (Kinase interacting with stathmin) (U2AF homology motif kinase 1).

VSIG2_MOUSE
θ value	2.88788e-06 (rank : 903)	NC score	0.371145 (rank : 966)
Query Neighborhood Hits	2923	Target Neighborhood Hits	316	Shared Neighborhood Hits	264
SwissProt Accessions	Q9Z109, Q9CVA4, Q9D0T4	Gene names	Vsig2, Ctm, Ctxl
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 2 precursor (CT- like protein) (Cortical thymocyte-like protein).

ADDB_MOUSE
θ value	3.77169e-06 (rank : 904)	NC score	0.048126 (rank : 1730)
Query Neighborhood Hits	2923	Target Neighborhood Hits	574	Shared Neighborhood Hits	248
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

BLK_HUMAN
θ value	3.77169e-06 (rank : 905)	NC score	0.571574 (rank : 706)
Query Neighborhood Hits	2923	Target Neighborhood Hits	994	Shared Neighborhood Hits	783
SwissProt Accessions	P51451, Q16291	Gene names	BLK
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

CDK9_MOUSE
θ value	3.77169e-06 (rank : 906)	NC score	0.674041 (rank : 482)
Query Neighborhood Hits	2923	Target Neighborhood Hits	822	Shared Neighborhood Hits	766
SwissProt Accessions	Q99J95, Q3U002, Q3UMY2, Q3UPT3, Q3UQI6, Q8BTN0	Gene names	Cdk9
Domain Architecture	No domain graphic available
Description	Cell division protein kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (Cyclin- dependent kinase 9).

LIMK1_MOUSE
θ value	3.77169e-06 (rank : 907)	NC score	0.627685 (rank : 588)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1008	Shared Neighborhood Hits	789
SwissProt Accessions	P53668	Gene names	Limk1, Limk
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (KIZ-1).

LRRN5_HUMAN
θ value	3.77169e-06 (rank : 908)	NC score	0.196355 (rank : 1088)
Query Neighborhood Hits	2923	Target Neighborhood Hits	493	Shared Neighborhood Hits	266
SwissProt Accessions	O75325, Q5T0Y0, Q6UXM0, Q8N182	Gene names	LRRN5, GAC1, LRRN2
Domain Architecture
Description	Leucine-rich repeats neuronal protein 5 precursor (Glioma amplified on chromosome 1 protein).

MP2K3_HUMAN
θ value	3.77169e-06 (rank : 909)	NC score	0.677691 (rank : 466)
Query Neighborhood Hits	2923	Target Neighborhood Hits	825	Shared Neighborhood Hits	769
SwissProt Accessions	P46734, Q99441, Q9UE71, Q9UE72	Gene names	MAP2K3, MEK3, MKK3, PRKMK3
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 3 (EC 2.7.12.2) (MAP kinase kinase 3) (MAPKK 3) (MAPK/ERK kinase 3).

CILP1_HUMAN
θ value	4.92598e-06 (rank : 910)	NC score	0.209284 (rank : 1067)
Query Neighborhood Hits	2923	Target Neighborhood Hits	266	Shared Neighborhood Hits	184
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

CSK_MOUSE
θ value	4.92598e-06 (rank : 911)	NC score	0.591399 (rank : 656)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1009	Shared Neighborhood Hits	788
SwissProt Accessions	P41241, Q03143	Gene names	Csk
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase MPK-2) (p50CSK).

KC1AL_HUMAN
θ value	4.92598e-06 (rank : 912)	NC score	0.555873 (rank : 738)
Query Neighborhood Hits	2923	Target Neighborhood Hits	734	Shared Neighborhood Hits	709
SwissProt Accessions	Q8N752	Gene names	CSNK1A1L
Domain Architecture
Description	Casein kinase I isoform alpha-like (EC 2.7.11.1) (CKI-alpha-like) (CK1).

MFA3L_HUMAN
θ value	4.92598e-06 (rank : 913)	NC score	0.347392 (rank : 978)
Query Neighborhood Hits	2923	Target Neighborhood Hits	230	Shared Neighborhood Hits	220
SwissProt Accessions	O75121, Q6TNA8, Q9BVE1, Q9BXK0	Gene names	MFAP3L, KIAA0626
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 3-like precursor (Protein kinase NYD-SP9).

PTPRM_MOUSE
θ value	4.92598e-06 (rank : 914)	NC score	0.182172 (rank : 1101)
Query Neighborhood Hits	2923	Target Neighborhood Hits	238	Shared Neighborhood Hits	175
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

UHMK1_MOUSE
θ value	4.92598e-06 (rank : 915)	NC score	0.674260 (rank : 479)
Query Neighborhood Hits	2923	Target Neighborhood Hits	809	Shared Neighborhood Hits	747
SwissProt Accessions	P97343, Q61775, Q9CYT1	Gene names	Uhmk1, Kis, Kist
Domain Architecture
Description	Serine/threonine-protein kinase Kist (EC 2.7.11.1) (Kinase interacting with stathmin) (U2AF homology motif kinase 1).

ERN1_HUMAN
θ value	6.43352e-06 (rank : 916)	NC score	0.680216 (rank : 462)
Query Neighborhood Hits	2923	Target Neighborhood Hits	829	Shared Neighborhood Hits	772
SwissProt Accessions	O75460	Gene names	ERN1, IRE1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase/endoribonuclease IRE1 precursor (Inositol-requiring protein 1) (hIRE1p) (IRE1a) (Ire1-alpha) (Endoplasmic reticulum-to-nucleus signaling 1) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)].

ERN2_MOUSE
θ value	6.43352e-06 (rank : 917)	NC score	0.667591 (rank : 503)
Query Neighborhood Hits	2923	Target Neighborhood Hits	825	Shared Neighborhood Hits	766
SwissProt Accessions	Q9Z2E3	Gene names	Ern2, Ire2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase/endoribonuclease IRE2 precursor (Inositol-requiring protein 2) (IRE1b) (Ire1-beta) (Endoplasmic reticulum-to-nucleus signaling 2) (mIre1) [Includes: Serine/threonine- protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)].

HCFC2_HUMAN
θ value	6.43352e-06 (rank : 918)	NC score	0.123198 (rank : 1165)
Query Neighborhood Hits	2923	Target Neighborhood Hits	154	Shared Neighborhood Hits	99
SwissProt Accessions	Q9Y5Z7	Gene names	HCFC2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

RGS3_MOUSE
θ value	6.43352e-06 (rank : 919)	NC score	0.063756 (rank : 1363)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1621	Shared Neighborhood Hits	506
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SIGL8_HUMAN
θ value	6.43352e-06 (rank : 920)	NC score	0.262385 (rank : 1026)
Query Neighborhood Hits	2923	Target Neighborhood Hits	252	Shared Neighborhood Hits	234
SwissProt Accessions	Q9NYZ4, Q7Z728	Gene names	SIGLEC8, SAF2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 8 precursor (Siglec-8) (Sialoadhesin family member 2) (SAF-2) (CDw329 antigen).

TESK1_HUMAN
θ value	6.43352e-06 (rank : 921)	NC score	0.653121 (rank : 543)
Query Neighborhood Hits	2923	Target Neighborhood Hits	864	Shared Neighborhood Hits	775
SwissProt Accessions	Q15569	Gene names	TESK1
Domain Architecture
Description	Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein kinase 1).

TESK1_MOUSE
θ value	6.43352e-06 (rank : 922)	NC score	0.654549 (rank : 536)
Query Neighborhood Hits	2923	Target Neighborhood Hits	862	Shared Neighborhood Hits	780
SwissProt Accessions	O70146, O70147	Gene names	Tesk1
Domain Architecture
Description	Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein kinase 1).

F5006_MOUSE
θ value	8.40245e-06 (rank : 923)	NC score	0.691897 (rank : 378)
Query Neighborhood Hits	2923	Target Neighborhood Hits	793	Shared Neighborhood Hits	753
SwissProt Accessions	Q5SYL1	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase FLJ25006 (EC 2.7.11.1).

FCERA_HUMAN
θ value	8.40245e-06 (rank : 924)	NC score	0.189992 (rank : 1096)
Query Neighborhood Hits	2923	Target Neighborhood Hits	150	Shared Neighborhood Hits	137
SwissProt Accessions	P12319	Gene names	FCER1A, FCE1A
Domain Architecture
Description	High affinity immunoglobulin epsilon receptor alpha-subunit precursor (FcERI) (IgE Fc receptor, alpha-subunit) (Fc-epsilon RI-alpha).

KSR2_HUMAN
θ value	8.40245e-06 (rank : 925)	NC score	0.623773 (rank : 594)
Query Neighborhood Hits	2923	Target Neighborhood Hits	920	Shared Neighborhood Hits	804
SwissProt Accessions	Q6VAB6, Q8N775	Gene names	KSR2
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-2 (hKSR2).

LRC4B_HUMAN
θ value	8.40245e-06 (rank : 926)	NC score	0.163137 (rank : 1123)
Query Neighborhood Hits	2923	Target Neighborhood Hits	479	Shared Neighborhood Hits	252
SwissProt Accessions	Q9NT99, Q3ZCQ4, Q58F20	Gene names	LRRC4B, LRIG4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4B precursor.

LRC4B_MOUSE
θ value	8.40245e-06 (rank : 927)	NC score	0.164843 (rank : 1118)
Query Neighborhood Hits	2923	Target Neighborhood Hits	484	Shared Neighborhood Hits	258
SwissProt Accessions	P0C192	Gene names	Lrrc4b, Lrig4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4B precursor.

RPKL1_MOUSE
θ value	8.40245e-06 (rank : 928)	NC score	0.597629 (rank : 643)
Query Neighborhood Hits	2923	Target Neighborhood Hits	704	Shared Neighborhood Hits	658
SwissProt Accessions	Q8R2S1, Q8R1D4	Gene names	Rps6kl1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase-like 1 (EC 2.7.11.1).

UFO_MOUSE
θ value	8.40245e-06 (rank : 929)	NC score	0.617305 (rank : 605)
Query Neighborhood Hits	2923	Target Neighborhood Hits	988	Shared Neighborhood Hits	899
SwissProt Accessions	Q00993	Gene names	Axl, Ark, Ufo
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (Adhesion-related kinase).

CD166_MOUSE
θ value	1.09739e-05 (rank : 930)	NC score	0.344537 (rank : 981)
Query Neighborhood Hits	2923	Target Neighborhood Hits	252	Shared Neighborhood Hits	234
SwissProt Accessions	Q61490, O70136, Q8CDA5, Q8R2T0	Gene names	Alcam
Domain Architecture
Description	CD166 antigen precursor (Activated leukocyte-cell adhesion molecule) (ALCAM) (DM-GRASP protein).

EPHB6_HUMAN
θ value	1.09739e-05 (rank : 931)	NC score	0.511224 (rank : 833)
Query Neighborhood Hits	2923	Target Neighborhood Hits	912	Shared Neighborhood Hits	754
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

ESAM_HUMAN
θ value	1.09739e-05 (rank : 932)	NC score	0.301398 (rank : 1001)
Query Neighborhood Hits	2923	Target Neighborhood Hits	251	Shared Neighborhood Hits	218
SwissProt Accessions	Q96AP7, Q96T50	Gene names	ESAM
Domain Architecture	No domain graphic available
Description	Endothelial cell-selective adhesion molecule precursor.

FLT3_MOUSE
θ value	1.09739e-05 (rank : 933)	NC score	0.543935 (rank : 770)
Query Neighborhood Hits	2923	Target Neighborhood Hits	847	Shared Neighborhood Hits	791
SwissProt Accessions	Q00342	Gene names	Flt3, Flk-2, Flt-3
Domain Architecture
Description	FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor flk-2) (Fetal liver kinase 2) (Tyrosine-protein kinase FLT3) (CD135 antigen).

KAZD1_MOUSE
θ value	1.09739e-05 (rank : 934)	NC score	0.351633 (rank : 974)
Query Neighborhood Hits	2923	Target Neighborhood Hits	281	Shared Neighborhood Hits	209
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).

LRFN4_MOUSE
θ value	1.09739e-05 (rank : 935)	NC score	0.241525 (rank : 1039)
Query Neighborhood Hits	2923	Target Neighborhood Hits	442	Shared Neighborhood Hits	240
SwissProt Accessions	Q80XU8, Q3TQG8, Q8K3C4	Gene names	Lrfn4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursor.

MAP1A_HUMAN
θ value	1.09739e-05 (rank : 936)	NC score	0.096524 (rank : 1216)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1626	Shared Neighborhood Hits	667
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

NTRK1_HUMAN
θ value	1.09739e-05 (rank : 937)	NC score	0.577809 (rank : 690)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1023	Shared Neighborhood Hits	857
SwissProt Accessions	P04629, P08119, Q15655, Q15656, Q5D056, Q5VZS2, Q9UIU7	Gene names	NTRK1, TRK
Domain Architecture
Description	High affinity nerve growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1 transforming tyrosine kinase protein) (p140-TrkA) (Trk-A).

UFO_HUMAN
θ value	1.09739e-05 (rank : 938)	NC score	0.608960 (rank : 617)
Query Neighborhood Hits	2923	Target Neighborhood Hits	981	Shared Neighborhood Hits	896
SwissProt Accessions	P30530	Gene names	AXL, UFO
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (AXL oncogene).

FGR_MOUSE
θ value	1.43324e-05 (rank : 939)	NC score	0.555100 (rank : 742)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1069	Shared Neighborhood Hits	796
SwissProt Accessions	P14234, Q61404	Gene names	Fgr
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

GPA33_MOUSE
θ value	1.43324e-05 (rank : 940)	NC score	0.339946 (rank : 985)
Query Neighborhood Hits	2923	Target Neighborhood Hits	294	Shared Neighborhood Hits	252
SwissProt Accessions	Q9JKA5, Q922D5	Gene names	Gpa33
Domain Architecture
Description	Cell surface A33 antigen precursor (Glycoprotein A33) (mA33).

SIGL5_MOUSE
θ value	1.43324e-05 (rank : 941)	NC score	0.317628 (rank : 996)
Query Neighborhood Hits	2923	Target Neighborhood Hits	271	Shared Neighborhood Hits	258
SwissProt Accessions	Q920G3	Gene names	Siglec5, Siglecf
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 5 precursor (Siglec-5) (Sialic acid-binding Ig-like lectin-F) (mSiglec-F).

SYTL2_HUMAN
θ value	1.43324e-05 (rank : 942)	NC score	0.027026 (rank : 2062)
Query Neighborhood Hits	2923	Target Neighborhood Hits	248	Shared Neighborhood Hits	81
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

WEE1B_MOUSE
θ value	1.43324e-05 (rank : 943)	NC score	0.638523 (rank : 576)
Query Neighborhood Hits	2923	Target Neighborhood Hits	765	Shared Neighborhood Hits	715
SwissProt Accessions	Q66JT0, Q4U4S4, Q7TPV9	Gene names	Wee1b, Wee2
Domain Architecture	No domain graphic available
Description	Wee1-like protein kinase 1B (EC 2.7.10.2) (Wee1B kinase) (mWee1B).

BMP2K_MOUSE
θ value	1.87187e-05 (rank : 944)	NC score	0.664119 (rank : 515)
Query Neighborhood Hits	2923	Target Neighborhood Hits	874	Shared Neighborhood Hits	761
SwissProt Accessions	Q91Z96, Q8C8L7	Gene names	Bmp2k, Bike
Domain Architecture
Description	BMP-2-inducible protein kinase (EC 2.7.11.1) (BIKe).

FYN_HUMAN
θ value	1.87187e-05 (rank : 945)	NC score	0.568559 (rank : 711)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1078	Shared Neighborhood Hits	794
SwissProt Accessions	P06241	Gene names	FYN
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK).

K1802_HUMAN
θ value	1.87187e-05 (rank : 946)	NC score	0.037059 (rank : 1888)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1378	Shared Neighborhood Hits	365
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

LRRN3_HUMAN
θ value	1.87187e-05 (rank : 947)	NC score	0.207371 (rank : 1069)
Query Neighborhood Hits	2923	Target Neighborhood Hits	461	Shared Neighborhood Hits	249
SwissProt Accessions	Q9H3W5, O43377, Q6I9V8, Q8IYQ6	Gene names	LRRN3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 3 precursor (Neuronal leucine- rich repeat protein 3) (NLRR-3).

PTPRB_HUMAN
θ value	1.87187e-05 (rank : 948)	NC score	0.131215 (rank : 1156)
Query Neighborhood Hits	2923	Target Neighborhood Hits	242	Shared Neighborhood Hits	132
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

STK35_HUMAN
θ value	1.87187e-05 (rank : 949)	NC score	0.695228 (rank : 346)
Query Neighborhood Hits	2923	Target Neighborhood Hits	825	Shared Neighborhood Hits	767
SwissProt Accessions	Q8TDR2, Q5T3R1, Q5T3R2, Q96AB4, Q9BZ06	Gene names	STK35, CLIK1, PDIK1
Domain Architecture
Description	Serine/threonine-protein kinase 35 (EC 2.7.11.1) (CLP-36-interacting kinase) (Clik1) (PDLIM1-interacting kinase 1).

I12R2_MOUSE
θ value	2.44474e-05 (rank : 950)	NC score	0.201779 (rank : 1079)
Query Neighborhood Hits	2923	Target Neighborhood Hits	143	Shared Neighborhood Hits	127
SwissProt Accessions	P97378	Gene names	Il12rb2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

LRC21_HUMAN
θ value	2.44474e-05 (rank : 951)	NC score	0.230812 (rank : 1045)
Query Neighborhood Hits	2923	Target Neighborhood Hits	456	Shared Neighborhood Hits	257
SwissProt Accessions	Q9P2V4, Q9Y4N7	Gene names	LRRC21, PAL
Domain Architecture
Description	Leucine-rich repeat-containing protein 21 precursor (Photoreceptor- associated LRR superfamily protein) (Retina-specific protein PAL).

LRC21_MOUSE
θ value	2.44474e-05 (rank : 952)	NC score	0.232894 (rank : 1042)
Query Neighborhood Hits	2923	Target Neighborhood Hits	462	Shared Neighborhood Hits	262
SwissProt Accessions	Q8K099, Q8BXN3	Gene names	Lrrc21, Pal
Domain Architecture
Description	Leucine-rich repeat-containing protein 21 precursor (Photoreceptor- associated LRR superfamily protein) (Retina-specific protein PAL).

LRRN1_HUMAN
θ value	2.44474e-05 (rank : 953)	NC score	0.204646 (rank : 1073)
Query Neighborhood Hits	2923	Target Neighborhood Hits	518	Shared Neighborhood Hits	289
SwissProt Accessions	Q6UXK5, Q3LID5, Q8IYV5, Q9H8V1, Q9P231	Gene names	LRRN1, KIAA1497
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 1 precursor (Neuronal leucine- rich repeat protein 1) (NLRR-1).

M3K7_HUMAN
θ value	2.44474e-05 (rank : 954)	NC score	0.654099 (rank : 539)
Query Neighborhood Hits	2923	Target Neighborhood Hits	892	Shared Neighborhood Hits	798
SwissProt Accessions	O43318, O43317, O43319, Q5TDN2, Q5TDN3	Gene names	MAP3K7, TAK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta- activated kinase 1).

M3K7_MOUSE
θ value	2.44474e-05 (rank : 955)	NC score	0.654259 (rank : 538)
Query Neighborhood Hits	2923	Target Neighborhood Hits	892	Shared Neighborhood Hits	799
SwissProt Accessions	Q62073	Gene names	Map3k7, Tak1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta- activated kinase 1).

MFA3L_MOUSE
θ value	2.44474e-05 (rank : 956)	NC score	0.297242 (rank : 1004)
Query Neighborhood Hits	2923	Target Neighborhood Hits	214	Shared Neighborhood Hits	203
SwissProt Accessions	Q9D3X9, Q80TV6, Q8BJA9	Gene names	Mfap3l, Kiaa0626
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 3-like precursor.

MP2K7_HUMAN
θ value	2.44474e-05 (rank : 957)	NC score	0.687144 (rank : 417)
Query Neighborhood Hits	2923	Target Neighborhood Hits	833	Shared Neighborhood Hits	776
SwissProt Accessions	O14733, O14648, O14816, O60452, O60453	Gene names	MAP2K7, JNKK2, MKK7, PRKMK7
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 7 (EC 2.7.12.2) (MAP kinase kinase 7) (MAPKK 7) (MAPK/ERK kinase 7) (JNK-activating kinase 2) (c-Jun N-terminal kinase kinase 2) (JNK kinase 2) (JNKK 2).

RET_HUMAN
θ value	2.44474e-05 (rank : 958)	NC score	0.575084 (rank : 697)
Query Neighborhood Hits	2923	Target Neighborhood Hits	873	Shared Neighborhood Hits	774
SwissProt Accessions	P07949, Q15250	Gene names	RET
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

RGS3_HUMAN
θ value	2.44474e-05 (rank : 959)	NC score	0.054131 (rank : 1608)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1375	Shared Neighborhood Hits	401
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

SPRR3_HUMAN
θ value	2.44474e-05 (rank : 960)	NC score	0.064458 (rank : 1349)
Query Neighborhood Hits	2923	Target Neighborhood Hits	102	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UBC9, O75597, Q4ZGI7, Q5T525, Q8NET7, Q9UDG3	Gene names	SPRR3, SPRC
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta) (Esophagin) (22 kDa pancornulin).

UNC5D_HUMAN
θ value	2.44474e-05 (rank : 961)	NC score	0.202630 (rank : 1077)
Query Neighborhood Hits	2923	Target Neighborhood Hits	267	Shared Neighborhood Hits	191
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

UNC5D_MOUSE
θ value	2.44474e-05 (rank : 962)	NC score	0.205157 (rank : 1071)
Query Neighborhood Hits	2923	Target Neighborhood Hits	268	Shared Neighborhood Hits	192
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

WEE1B_HUMAN
θ value	2.44474e-05 (rank : 963)	NC score	0.637401 (rank : 578)
Query Neighborhood Hits	2923	Target Neighborhood Hits	836	Shared Neighborhood Hits	746
SwissProt Accessions	P0C1S8	Gene names	WEE1B, WEE2
Domain Architecture	No domain graphic available
Description	Wee1-like protein kinase 1B (EC 2.7.10.2) (Wee1B kinase).

IL1R2_HUMAN
θ value	3.19293e-05 (rank : 964)	NC score	0.258063 (rank : 1028)
Query Neighborhood Hits	2923	Target Neighborhood Hits	153	Shared Neighborhood Hits	150
SwissProt Accessions	P27930, Q9UE68	Gene names	IL1R2, IL1RB
Domain Architecture
Description	Interleukin-1 receptor type II precursor (IL-1R-2) (IL-1R-beta) (CD121b antigen) (CDw121b).

LRRN3_MOUSE
θ value	3.19293e-05 (rank : 965)	NC score	0.196503 (rank : 1087)
Query Neighborhood Hits	2923	Target Neighborhood Hits	455	Shared Neighborhood Hits	245
SwissProt Accessions	Q8CBC6, P97860	Gene names	Lrrn3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 3 precursor (Neuronal leucine- rich repeat protein 3) (NLRR-3).

PTPRK_HUMAN
θ value	3.19293e-05 (rank : 966)	NC score	0.147044 (rank : 1139)
Query Neighborhood Hits	2923	Target Neighborhood Hits	228	Shared Neighborhood Hits	158
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

SEPT9_HUMAN
θ value	3.19293e-05 (rank : 967)	NC score	0.035938 (rank : 1904)
Query Neighborhood Hits	2923	Target Neighborhood Hits	706	Shared Neighborhood Hits	261
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

SLAF5_MOUSE
θ value	3.19293e-05 (rank : 968)	NC score	0.074065 (rank : 1285)
Query Neighborhood Hits	2923	Target Neighborhood Hits	93	Shared Neighborhood Hits	77
SwissProt Accessions	Q18PI6, Q18PI7, Q3TBT1, Q3U0A2, Q8BFV0, Q9Z178	Gene names	Cd84, Slamf5
Domain Architecture	No domain graphic available
Description	SLAM family member 5 precursor (Signaling lymphocytic activation molecule 5) (Leukocyte differentiation antigen CD84) (CD84 antigen).

TARSH_HUMAN
θ value	3.19293e-05 (rank : 969)	NC score	0.190086 (rank : 1095)
Query Neighborhood Hits	2923	Target Neighborhood Hits	768	Shared Neighborhood Hits	381
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

TESK2_HUMAN
θ value	3.19293e-05 (rank : 970)	NC score	0.653949 (rank : 540)
Query Neighborhood Hits	2923	Target Neighborhood Hits	851	Shared Neighborhood Hits	771
SwissProt Accessions	Q96S53, Q8N520, Q9Y3Q6	Gene names	TESK2
Domain Architecture
Description	Dual specificity testis-specific protein kinase 2 (EC 2.7.12.1) (Testicular protein kinase 2).

YES_HUMAN
θ value	3.19293e-05 (rank : 971)	NC score	0.560776 (rank : 722)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1059	Shared Neighborhood Hits	793
SwissProt Accessions	P07947	Gene names	YES1, YES
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

AN30A_HUMAN
θ value	4.1701e-05 (rank : 972)	NC score	0.060645 (rank : 1424)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1119	Shared Neighborhood Hits	424
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

CILP2_HUMAN
θ value	4.1701e-05 (rank : 973)	NC score	0.249943 (rank : 1031)
Query Neighborhood Hits	2923	Target Neighborhood Hits	307	Shared Neighborhood Hits	211
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

GPA33_HUMAN
θ value	4.1701e-05 (rank : 974)	NC score	0.324936 (rank : 993)
Query Neighborhood Hits	2923	Target Neighborhood Hits	273	Shared Neighborhood Hits	238
SwissProt Accessions	Q99795	Gene names	GPA33
Domain Architecture
Description	Cell surface A33 antigen precursor (Glycoprotein A33).

HEMGN_HUMAN
θ value	4.1701e-05 (rank : 975)	NC score	0.043334 (rank : 1790)
Query Neighborhood Hits	2923	Target Neighborhood Hits	92	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BXL5, Q6XAR3, Q86XY5, Q9NPC0	Gene names	HEMGN, EDAG, NDR
Domain Architecture	No domain graphic available
Description	Hemogen (Hemopoietic gene protein) (Negative differentiation regulator protein) (Erythroid differentiation-associated gene protein) (EDAG-1).

KAZD1_HUMAN
θ value	4.1701e-05 (rank : 976)	NC score	0.318131 (rank : 995)
Query Neighborhood Hits	2923	Target Neighborhood Hits	248	Shared Neighborhood Hits	174
SwissProt Accessions	Q96I82, Q6ZMB1, Q9BQ73	Gene names	KAZALD1
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor.

LIFR_HUMAN
θ value	4.1701e-05 (rank : 977)	NC score	0.198629 (rank : 1082)
Query Neighborhood Hits	2923	Target Neighborhood Hits	130	Shared Neighborhood Hits	108
SwissProt Accessions	P42702, Q6LCD9	Gene names	LIFR
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (CD118 antigen).

PTPRJ_MOUSE
θ value	4.1701e-05 (rank : 978)	NC score	0.107327 (rank : 1187)
Query Neighborhood Hits	2923	Target Neighborhood Hits	188	Shared Neighborhood Hits	111
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

YES_MOUSE
θ value	4.1701e-05 (rank : 979)	NC score	0.560165 (rank : 725)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1052	Shared Neighborhood Hits	786
SwissProt Accessions	Q04736	Gene names	Yes1, Yes
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

CD244_HUMAN
θ value	5.44631e-05 (rank : 980)	NC score	0.095425 (rank : 1219)
Query Neighborhood Hits	2923	Target Neighborhood Hits	72	Shared Neighborhood Hits	56
SwissProt Accessions	Q9BZW8, Q96T47, Q9NQD2, Q9NQD3, Q9Y288	Gene names	CD244, 2B4
Domain Architecture
Description	Natural killer cell receptor 2B4 precursor (NKR2B4) (NK cell type I receptor protein 2B4) (h2B4) (CD244 antigen) (NK cell activation- inducing ligand) (NAIL).

JADE2_MOUSE
θ value	5.44631e-05 (rank : 981)	NC score	0.030447 (rank : 2000)
Query Neighborhood Hits	2923	Target Neighborhood Hits	560	Shared Neighborhood Hits	207
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

LRRC4_MOUSE
θ value	5.44631e-05 (rank : 982)	NC score	0.124739 (rank : 1163)
Query Neighborhood Hits	2923	Target Neighborhood Hits	412	Shared Neighborhood Hits	194
SwissProt Accessions	Q99PH1, Q8VI35	Gene names	Lrrc4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing 4 protein precursor (Brain tumor- associated protein MBAG1).

PTPRT_HUMAN
θ value	5.44631e-05 (rank : 983)	NC score	0.163531 (rank : 1122)
Query Neighborhood Hits	2923	Target Neighborhood Hits	217	Shared Neighborhood Hits	152
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

PTPRT_MOUSE
θ value	5.44631e-05 (rank : 984)	NC score	0.164220 (rank : 1121)
Query Neighborhood Hits	2923	Target Neighborhood Hits	219	Shared Neighborhood Hits	151
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

RTN4_HUMAN
θ value	5.44631e-05 (rank : 985)	NC score	0.051773 (rank : 1665)
Query Neighborhood Hits	2923	Target Neighborhood Hits	357	Shared Neighborhood Hits	186
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

TRIM1_MOUSE
θ value	5.44631e-05 (rank : 986)	NC score	0.040467 (rank : 1837)
Query Neighborhood Hits	2923	Target Neighborhood Hits	361	Shared Neighborhood Hits	131
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

CCNB3_HUMAN
θ value	7.1131e-05 (rank : 987)	NC score	0.045065 (rank : 1764)
Query Neighborhood Hits	2923	Target Neighborhood Hits	368	Shared Neighborhood Hits	196
SwissProt Accessions	Q8WWL7, Q96SB5, Q96SB6, Q96SB7, Q9NT38	Gene names	CCNB3, CYCB3
Domain Architecture
Description	G2/mitotic-specific cyclin-B3.

EPHB6_MOUSE
θ value	7.1131e-05 (rank : 988)	NC score	0.520948 (rank : 817)
Query Neighborhood Hits	2923	Target Neighborhood Hits	906	Shared Neighborhood Hits	769
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

FCGR1_MOUSE
θ value	7.1131e-05 (rank : 989)	NC score	0.166065 (rank : 1116)
Query Neighborhood Hits	2923	Target Neighborhood Hits	123	Shared Neighborhood Hits	112
SwissProt Accessions	P26151	Gene names	Fcgr1, Fcg1
Domain Architecture
Description	High affinity immunoglobulin gamma Fc receptor I precursor (Fc-gamma RI) (FcRI) (IgG Fc receptor I).

MOS_MOUSE
θ value	7.1131e-05 (rank : 990)	NC score	0.632442 (rank : 585)
Query Neighborhood Hits	2923	Target Neighborhood Hits	833	Shared Neighborhood Hits	773
SwissProt Accessions	P00536	Gene names	Mos
Domain Architecture	No domain graphic available
Description	Proto-oncogene serine/threonine-protein kinase mos (EC 2.7.11.1) (c- mos) (Oocyte maturation factor mos).

RAGE_HUMAN
θ value	7.1131e-05 (rank : 991)	NC score	0.424616 (rank : 916)
Query Neighborhood Hits	2923	Target Neighborhood Hits	269	Shared Neighborhood Hits	260
SwissProt Accessions	Q15109, Q15279, Q9H2X7, Q9Y3R3	Gene names	AGER, RAGE
Domain Architecture
Description	Advanced glycosylation end product-specific receptor precursor (Receptor for advanced glycosylation end products).

RPKL1_HUMAN
θ value	7.1131e-05 (rank : 992)	NC score	0.594344 (rank : 652)
Query Neighborhood Hits	2923	Target Neighborhood Hits	708	Shared Neighborhood Hits	649
SwissProt Accessions	Q9Y6S9, Q69YT9, Q6ZMQ6, Q96NR9, Q9BSU9	Gene names	RPS6KL1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase-like 1 (EC 2.7.11.1).

TRI18_HUMAN
θ value	7.1131e-05 (rank : 993)	NC score	0.037480 (rank : 1883)
Query Neighborhood Hits	2923	Target Neighborhood Hits	307	Shared Neighborhood Hits	93
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

BMP2K_HUMAN
θ value	9.29e-05 (rank : 994)	NC score	0.663035 (rank : 520)
Query Neighborhood Hits	2923	Target Neighborhood Hits	867	Shared Neighborhood Hits	772
SwissProt Accessions	Q9NSY1, O94791, Q8IYF2, Q8N2G7, Q8NHG9, Q9NTG8	Gene names	BMP2K, BIKE
Domain Architecture
Description	BMP-2-inducible protein kinase (EC 2.7.11.1) (BIKe).

CD276_MOUSE
θ value	9.29e-05 (rank : 995)	NC score	0.227886 (rank : 1053)
Query Neighborhood Hits	2923	Target Neighborhood Hits	243	Shared Neighborhood Hits	214
SwissProt Accessions	Q8VE98	Gene names	Cd276, B7h3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3).

CDC7_HUMAN
θ value	9.29e-05 (rank : 996)	NC score	0.593273 (rank : 653)
Query Neighborhood Hits	2923	Target Neighborhood Hits	652	Shared Neighborhood Hits	625
SwissProt Accessions	O00311, O00558	Gene names	CDC7, CDC7L1
Domain Architecture
Description	Cell division cycle 7-related protein kinase (EC 2.7.11.1) (CDC7- related kinase) (HsCdc7) (huCdc7).

CILP1_MOUSE
θ value	9.29e-05 (rank : 997)	NC score	0.221822 (rank : 1058)
Query Neighborhood Hits	2923	Target Neighborhood Hits	282	Shared Neighborhood Hits	207
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

ERN2_HUMAN
θ value	9.29e-05 (rank : 998)	NC score	0.671109 (rank : 489)
Query Neighborhood Hits	2923	Target Neighborhood Hits	844	Shared Neighborhood Hits	778
SwissProt Accessions	Q76MJ5, Q6ZNC0	Gene names	ERN2, IRE2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase/endoribonuclease IRE2 precursor (Inositol-requiring protein 2) (hIRE2p) (IRE1b) (Ire1-beta) (Endoplasmic reticulum-to-nucleus signaling 2) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)].

IL1AP_MOUSE
θ value	9.29e-05 (rank : 999)	NC score	0.088370 (rank : 1241)
Query Neighborhood Hits	2923	Target Neighborhood Hits	94	Shared Neighborhood Hits	67
SwissProt Accessions	Q61730, Q8VCB9	Gene names	Il1rap
Domain Architecture
Description	Interleukin-1 receptor accessory protein precursor (IL-1 receptor accessory protein) (IL-1RAcP).

IL1R2_MOUSE
θ value	9.29e-05 (rank : 1000)	NC score	0.218380 (rank : 1061)
Query Neighborhood Hits	2923	Target Neighborhood Hits	125	Shared Neighborhood Hits	117
SwissProt Accessions	P27931	Gene names	Il1r2, Il-1r2, Il1rb
Domain Architecture
Description	Interleukin-1 receptor type II precursor (IL-1R-2) (IL-1R-beta) (CD121b antigen).

IRPL1_HUMAN
θ value	9.29e-05 (rank : 1001)	NC score	0.216282 (rank : 1064)
Query Neighborhood Hits	2923	Target Neighborhood Hits	196	Shared Neighborhood Hits	183
SwissProt Accessions	Q9NZN1, Q9UJ53	Gene names	IL1RAPL1, OPHN4
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 1 precursor (IL1RAPL-1) (Oligophrenin-4) (Three immunoglobulin domain-containing IL-1 receptor-related 2) (TIGIRR-2).

LRRK2_HUMAN
θ value	9.29e-05 (rank : 1002)	NC score	0.591903 (rank : 654)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1382	Shared Neighborhood Hits	835
SwissProt Accessions	Q5S007, Q6ZS50, Q8NCX9	Gene names	LRRK2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin).

PSG5_HUMAN
θ value	9.29e-05 (rank : 1003)	NC score	0.271729 (rank : 1020)
Query Neighborhood Hits	2923	Target Neighborhood Hits	231	Shared Neighborhood Hits	223
SwissProt Accessions	Q15238, Q15239, Q96QJ1, Q9UQ75	Gene names	PSG5
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 5 precursor (PSBG-5) (Fetal liver non-specific cross-reactive antigen 3) (FL-NCA-3).

PTPRK_MOUSE
θ value	9.29e-05 (rank : 1004)	NC score	0.148822 (rank : 1138)
Query Neighborhood Hits	2923	Target Neighborhood Hits	223	Shared Neighborhood Hits	154
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

RET_MOUSE
θ value	9.29e-05 (rank : 1005)	NC score	0.573834 (rank : 698)
Query Neighborhood Hits	2923	Target Neighborhood Hits	884	Shared Neighborhood Hits	778
SwissProt Accessions	P35546, Q8BQ34, Q9QXH9	Gene names	Ret
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

SPR1A_MOUSE
θ value	9.29e-05 (rank : 1006)	NC score	0.049956 (rank : 1707)
Query Neighborhood Hits	2923	Target Neighborhood Hits	343	Shared Neighborhood Hits	119
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

SRC_HUMAN
θ value	9.29e-05 (rank : 1007)	NC score	0.563103 (rank : 719)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1058	Shared Neighborhood Hits	791
SwissProt Accessions	P12931, Q86VB9, Q9H5A8	Gene names	SRC, SRC1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c- Src) (pp60c-src).

ACINU_HUMAN
θ value	0.000121331 (rank : 1008)	NC score	0.090298 (rank : 1233)
Query Neighborhood Hits	2923	Target Neighborhood Hits	828	Shared Neighborhood Hits	417
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

IRPL1_MOUSE
θ value	0.000121331 (rank : 1009)	NC score	0.219995 (rank : 1059)
Query Neighborhood Hits	2923	Target Neighborhood Hits	186	Shared Neighborhood Hits	175
SwissProt Accessions	P59823	Gene names	Il1rapl1
Domain Architecture	No domain graphic available
Description	X-linked interleukin-1 receptor accessory protein-like 1 precursor (IL1RAPL-1).

LRRN1_MOUSE
θ value	0.000121331 (rank : 1010)	NC score	0.197539 (rank : 1085)
Query Neighborhood Hits	2923	Target Neighborhood Hits	508	Shared Neighborhood Hits	282
SwissProt Accessions	Q61809, Q3USY1, Q69ZI0	Gene names	Lrrn1, Kiaa1497
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 1 precursor (Neuronal leucine- rich repeat protein 1) (NLRR-1).

MAP2_HUMAN
θ value	0.000121331 (rank : 1011)	NC score	0.052883 (rank : 1641)
Query Neighborhood Hits	2923	Target Neighborhood Hits	348	Shared Neighborhood Hits	179
SwissProt Accessions	P11137, Q99975, Q99976	Gene names	MAP2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2) (MAP-2).

MOES_HUMAN
θ value	0.000121331 (rank : 1012)	NC score	0.050558 (rank : 1692)
Query Neighborhood Hits	2923	Target Neighborhood Hits	892	Shared Neighborhood Hits	368
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

MOES_MOUSE
θ value	0.000121331 (rank : 1013)	NC score	0.051140 (rank : 1680)
Query Neighborhood Hits	2923	Target Neighborhood Hits	923	Shared Neighborhood Hits	369
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

MOS_HUMAN
θ value	0.000121331 (rank : 1014)	NC score	0.636724 (rank : 579)
Query Neighborhood Hits	2923	Target Neighborhood Hits	829	Shared Neighborhood Hits	773
SwissProt Accessions	P00540	Gene names	MOS
Domain Architecture
Description	Proto-oncogene serine/threonine-protein kinase mos (EC 2.7.11.1) (c- mos) (Oocyte maturation factor mos).

SCYL2_HUMAN
θ value	0.000121331 (rank : 1015)	NC score	0.539469 (rank : 778)
Query Neighborhood Hits	2923	Target Neighborhood Hits	632	Shared Neighborhood Hits	575
SwissProt Accessions	Q6P3W7, Q96EF4, Q96ST4, Q9H7V5, Q9NVH3, Q9P2I7	Gene names	SCYL2, CVAK104, KIAA1360
Domain Architecture	No domain graphic available
Description	SCY1-like protein 2 (Coated vesicle-associated kinase of 104 kDa).

SEPT9_MOUSE
θ value	0.000121331 (rank : 1016)	NC score	0.023628 (rank : 2132)
Query Neighborhood Hits	2923	Target Neighborhood Hits	238	Shared Neighborhood Hits	87
SwissProt Accessions	Q80UG5, Q3URP2, Q80TM7, Q9QYX9	Gene names	Sept9, Kiaa0991, Sint1
Domain Architecture	No domain graphic available
Description	Septin-9 (SL3-3 integration site 1 protein).

HCFC2_MOUSE
θ value	0.000158464 (rank : 1017)	NC score	0.184776 (rank : 1099)
Query Neighborhood Hits	2923	Target Neighborhood Hits	97	Shared Neighborhood Hits	95
SwissProt Accessions	Q9D968	Gene names	Hcfc2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

LAG3_HUMAN
θ value	0.000158464 (rank : 1018)	NC score	0.141661 (rank : 1146)
Query Neighborhood Hits	2923	Target Neighborhood Hits	129	Shared Neighborhood Hits	100
SwissProt Accessions	P18627	Gene names	LAG3, FDC
Domain Architecture
Description	Lymphocyte activation gene 3 protein precursor (LAG-3) (FDC protein) (CD223 antigen).

RIPK5_HUMAN
θ value	0.000158464 (rank : 1019)	NC score	0.658961 (rank : 528)
Query Neighborhood Hits	2923	Target Neighborhood Hits	864	Shared Neighborhood Hits	792
SwissProt Accessions	Q6XUX3, O75060, Q5RKT0, Q6IN87, Q6P997, Q86Y03, Q9P1S5	Gene names	RIPK5, KIAA0472, RIP5
Domain Architecture	No domain graphic available
Description	Receptor-interacting serine/threonine-protein kinase 5 (EC 2.7.11.1) (Dusty protein kinase) (Dusty PK) (RIP-homologous kinase).

RIPK5_MOUSE
θ value	0.000158464 (rank : 1020)	NC score	0.658517 (rank : 530)
Query Neighborhood Hits	2923	Target Neighborhood Hits	874	Shared Neighborhood Hits	794
SwissProt Accessions	Q6XUX1, Q3ULK4, Q5EBN5, Q8C7D4, Q8C923, Q9CTP7	Gene names	Ripk5
Domain Architecture	No domain graphic available
Description	Receptor-interacting serine/threonine-protein kinase 5 (EC 2.7.11.1) (Dusty protein kinase) (Dusty PK).

SHPS1_HUMAN
θ value	0.000158464 (rank : 1021)	NC score	0.131903 (rank : 1155)
Query Neighborhood Hits	2923	Target Neighborhood Hits	455	Shared Neighborhood Hits	208
SwissProt Accessions	P78324, O00683, O43799, Q8N517, Q8TAL8, Q9H0Z2, Q9UDX2, Q9UIJ6, Q9Y4U9	Gene names	SIRPA, BIT, MFR, MYD1, PTPNS1, SHPS1, SIRP
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type substrate 1 precursor (SHP substrate 1) (SHPS-1) (Inhibitory receptor SHPS-1) (Signal- regulatory protein alpha-1) (Sirp-alpha-1) (Sirp-alpha-2) (Sirp-alpha- 3) (MyD-1 antigen) (Brain Ig-like molecule with tyrosine-based activation motifs) (Bit) (Macrophage fusion receptor) (p84) (CD172a antigen).

SIGL6_HUMAN
θ value	0.000158464 (rank : 1022)	NC score	0.246161 (rank : 1035)
Query Neighborhood Hits	2923	Target Neighborhood Hits	233	Shared Neighborhood Hits	222
SwissProt Accessions	O43699, O15388, O43700	Gene names	SIGLEC6, CD33L, CD33L1, OBBP1
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 6 precursor (Siglec-6) (Obesity- binding protein 1) (OB-BP1) (CD33 antigen-like 1) (CDw327 antigen).

TESK2_MOUSE
θ value	0.000158464 (rank : 1023)	NC score	0.653542 (rank : 542)
Query Neighborhood Hits	2923	Target Neighborhood Hits	833	Shared Neighborhood Hits	766
SwissProt Accessions	Q8VCT9	Gene names	Tesk2
Domain Architecture
Description	Dual specificity testis-specific protein kinase 2 (EC 2.7.12.1) (Testicular protein kinase 2).

TP53B_MOUSE
θ value	0.000158464 (rank : 1024)	NC score	0.065726 (rank : 1341)
Query Neighborhood Hits	2923	Target Neighborhood Hits	644	Shared Neighborhood Hits	277
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

ANK2_HUMAN
θ value	0.00020696 (rank : 1025)	NC score	0.045063 (rank : 1765)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1615	Shared Neighborhood Hits	546
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ANKF1_HUMAN
θ value	0.00020696 (rank : 1026)	NC score	0.109243 (rank : 1185)
Query Neighborhood Hits	2923	Target Neighborhood Hits	126	Shared Neighborhood Hits	60
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

CALD1_HUMAN
θ value	0.00020696 (rank : 1027)	NC score	0.081353 (rank : 1257)
Query Neighborhood Hits	2923	Target Neighborhood Hits	959	Shared Neighborhood Hits	417
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

CDC7_MOUSE
θ value	0.00020696 (rank : 1028)	NC score	0.588976 (rank : 666)
Query Neighborhood Hits	2923	Target Neighborhood Hits	641	Shared Neighborhood Hits	621
SwissProt Accessions	Q9Z0H0, Q9Z2Y7	Gene names	Cdc7, Cdc7l1
Domain Architecture
Description	Cell division cycle 7-related protein kinase (EC 2.7.11.1) (CDC7- related kinase) (muCdc7).

ECM1_MOUSE
θ value	0.00020696 (rank : 1029)	NC score	0.035805 (rank : 1910)
Query Neighborhood Hits	2923	Target Neighborhood Hits	105	Shared Neighborhood Hits	44
SwissProt Accessions	Q61508	Gene names	Ecm1
Domain Architecture
Description	Extracellular matrix protein 1 precursor (Secretory component p85).

ESAM_MOUSE
θ value	0.00020696 (rank : 1030)	NC score	0.269005 (rank : 1022)
Query Neighborhood Hits	2923	Target Neighborhood Hits	222	Shared Neighborhood Hits	204
SwissProt Accessions	Q925F2	Gene names	Esam, Esam1
Domain Architecture	No domain graphic available
Description	Endothelial cell-selective adhesion molecule precursor.

ETV3_HUMAN
θ value	0.00020696 (rank : 1031)	NC score	0.021976 (rank : 2170)
Query Neighborhood Hits	2923	Target Neighborhood Hits	312	Shared Neighborhood Hits	135
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

F5006_HUMAN
θ value	0.00020696 (rank : 1032)	NC score	0.687667 (rank : 414)
Query Neighborhood Hits	2923	Target Neighborhood Hits	794	Shared Neighborhood Hits	749
SwissProt Accessions	Q96LW2, Q49A48	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase FLJ25006 (EC 2.7.11.1).

KALM_HUMAN
θ value	0.00020696 (rank : 1033)	NC score	0.177265 (rank : 1106)
Query Neighborhood Hits	2923	Target Neighborhood Hits	114	Shared Neighborhood Hits	83
SwissProt Accessions	P23352	Gene names	KAL1, ADMLX, KAL, KALIG1
Domain Architecture
Description	Anosmin-1 precursor (Kallmann syndrome protein) (Adhesion molecule- like X-linked).

SIG12_MOUSE
θ value	0.00020696 (rank : 1034)	NC score	0.191581 (rank : 1092)
Query Neighborhood Hits	2923	Target Neighborhood Hits	225	Shared Neighborhood Hits	191
SwissProt Accessions	Q91Y57	Gene names	Siglec12, Siglec5, Siglece, Siglecl1
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 12 precursor (Siglec-12) (Sialic acid-binding Ig-like lectin-like 1) (Siglec-L1) (Sialic acid-binding Ig-like lectin 5) (Siglec-5) (mSiglec-E) (Myeloid inhibitory siglec) (MIS).

STYK1_HUMAN
θ value	0.00020696 (rank : 1035)	NC score	0.570727 (rank : 709)
Query Neighborhood Hits	2923	Target Neighborhood Hits	786	Shared Neighborhood Hits	735
SwissProt Accessions	Q6J9G0, Q9BXY2, Q9NSH1	Gene names	STYK1, NOK
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (Protein PK-unique).

UNC5A_MOUSE
θ value	0.00020696 (rank : 1036)	NC score	0.146844 (rank : 1140)
Query Neighborhood Hits	2923	Target Neighborhood Hits	203	Shared Neighborhood Hits	131
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

ANK3_HUMAN
θ value	0.000270298 (rank : 1037)	NC score	0.017009 (rank : 2263)
Query Neighborhood Hits	2923	Target Neighborhood Hits	853	Shared Neighborhood Hits	278
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

FYN_MOUSE
θ value	0.000270298 (rank : 1038)	NC score	0.563894 (rank : 718)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1073	Shared Neighborhood Hits	795
SwissProt Accessions	P39688	Gene names	Fyn
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn).

MYO9B_HUMAN
θ value	0.000270298 (rank : 1039)	NC score	0.050564 (rank : 1691)
Query Neighborhood Hits	2923	Target Neighborhood Hits	641	Shared Neighborhood Hits	268
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

SCYL2_MOUSE
θ value	0.000270298 (rank : 1040)	NC score	0.523462 (rank : 812)
Query Neighborhood Hits	2923	Target Neighborhood Hits	603	Shared Neighborhood Hits	552
SwissProt Accessions	Q8CFE4, Q3UT57, Q3UWU9, Q8K0M4	Gene names	Scyl2, Cvak104, D10Ertd802e
Domain Architecture	No domain graphic available
Description	SCY1-like protein 2 (Coated vesicle-associated kinase of 104 kDa).

CI096_HUMAN
θ value	0.00035302 (rank : 1041)	NC score	0.671975 (rank : 488)
Query Neighborhood Hits	2923	Target Neighborhood Hits	821	Shared Neighborhood Hits	763
SwissProt Accessions	Q8NE28, Q5T8U8	Gene names	C9orf96
Domain Architecture	No domain graphic available
Description	Protein kinase-like protein C9orf96.

E2AK3_HUMAN
θ value	0.00035302 (rank : 1042)	NC score	0.673118 (rank : 486)
Query Neighborhood Hits	2923	Target Neighborhood Hits	859	Shared Neighborhood Hits	785
SwissProt Accessions	Q9NZJ5, O95846	Gene names	EIF2AK3, PEK, PERK
Domain Architecture
Description	Eukaryotic translation initiation factor 2-alpha kinase 3 precursor (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase) (HsPEK).

ILRL1_HUMAN
θ value	0.00035302 (rank : 1043)	NC score	0.176397 (rank : 1107)
Query Neighborhood Hits	2923	Target Neighborhood Hits	167	Shared Neighborhood Hits	141
SwissProt Accessions	Q01638, Q53TU7, Q8NEJ3, Q9ULV7, Q9UQ44	Gene names	IL1RL1, DER4, ST2, T1
Domain Architecture
Description	Interleukin-1 receptor-like 1 precursor (ST2 protein).

ILRL2_HUMAN
θ value	0.00035302 (rank : 1044)	NC score	0.134851 (rank : 1154)
Query Neighborhood Hits	2923	Target Neighborhood Hits	112	Shared Neighborhood Hits	105
SwissProt Accessions	Q9HB29, Q13525, Q45H74	Gene names	IL1RL2, IL1RRP2
Domain Architecture
Description	Interleukin-1 receptor-like 2 precursor (IL-1Rrp2) (Interleukin-1 receptor-related protein 2) (IL1R-rp2).

KC1A_HUMAN
θ value	0.00035302 (rank : 1045)	NC score	0.556442 (rank : 733)
Query Neighborhood Hits	2923	Target Neighborhood Hits	728	Shared Neighborhood Hits	712
SwissProt Accessions	P48729, Q96HD2	Gene names	CSNK1A1
Domain Architecture
Description	Casein kinase I isoform alpha (EC 2.7.11.1) (CKI-alpha) (CK1).

KC1A_MOUSE
θ value	0.00035302 (rank : 1046)	NC score	0.556442 (rank : 734)
Query Neighborhood Hits	2923	Target Neighborhood Hits	728	Shared Neighborhood Hits	712
SwissProt Accessions	Q8BK63, Q3UIL0, Q64506, Q80XI2, Q99LY3	Gene names	Csnk1a1
Domain Architecture
Description	Casein kinase I isoform alpha (EC 2.7.11.1) (CKI-alpha) (CK1).

PIGR_MOUSE
θ value	0.00035302 (rank : 1047)	NC score	0.202187 (rank : 1078)
Query Neighborhood Hits	2923	Target Neighborhood Hits	214	Shared Neighborhood Hits	172
SwissProt Accessions	O70570	Gene names	Pigr
Domain Architecture
Description	Polymeric-immunoglobulin receptor precursor (Poly-Ig receptor) (PIGR) [Contains: Secretory component].

PVR_HUMAN
θ value	0.00035302 (rank : 1048)	NC score	0.204491 (rank : 1074)
Query Neighborhood Hits	2923	Target Neighborhood Hits	195	Shared Neighborhood Hits	168
SwissProt Accessions	P15151, P15152, Q15267, Q15268, Q96BJ1	Gene names	PVR, PVS
Domain Architecture
Description	Poliovirus receptor precursor (Nectin-like protein 5) (Necl-5) (CD155 antigen).

SRC_MOUSE
θ value	0.00035302 (rank : 1049)	NC score	0.564438 (rank : 716)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1033	Shared Neighborhood Hits	785
SwissProt Accessions	P05480	Gene names	Src
Domain Architecture
Description	Neuronal proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c-Src) (pp60c-src).

AKAP9_HUMAN
θ value	0.000461057 (rank : 1050)	NC score	0.065195 (rank : 1345)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1710	Shared Neighborhood Hits	542
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

CP135_MOUSE
θ value	0.000461057 (rank : 1051)	NC score	0.062660 (rank : 1384)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1278	Shared Neighborhood Hits	451
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

E2AK3_MOUSE
θ value	0.000461057 (rank : 1052)	NC score	0.670069 (rank : 492)
Query Neighborhood Hits	2923	Target Neighborhood Hits	851	Shared Neighborhood Hits	788
SwissProt Accessions	Q9Z2B5, Q9CTK8, Q9CWT5	Gene names	Eif2ak3, Pek, Perk
Domain Architecture
Description	Eukaryotic translation initiation factor 2-alpha kinase 3 precursor (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase).

GP158_MOUSE
θ value	0.000461057 (rank : 1053)	NC score	0.022268 (rank : 2164)
Query Neighborhood Hits	2923	Target Neighborhood Hits	82	Shared Neighborhood Hits	24
SwissProt Accessions	Q8C419, Q8CHB0	Gene names	Gpr158, Kiaa1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

GTF2I_HUMAN
θ value	0.000461057 (rank : 1054)	NC score	0.024632 (rank : 2114)
Query Neighborhood Hits	2923	Target Neighborhood Hits	151	Shared Neighborhood Hits	61
SwissProt Accessions	P78347, O14743, O15359, O43546, O43588, O43589, Q9BSZ4	Gene names	GTF2I, BAP135, WBSCR6
Domain Architecture
Description	General transcription factor II-I (GTFII-I) (TFII-I) (Bruton tyrosine kinase-associated protein 135) (BTK-associated protein 135) (BAP-135) (SRF-Phox1-interacting protein) (SPIN) (Williams-Beuren syndrome chromosome region 6 protein).

RADI_HUMAN
θ value	0.000461057 (rank : 1055)	NC score	0.045222 (rank : 1762)
Query Neighborhood Hits	2923	Target Neighborhood Hits	741	Shared Neighborhood Hits	316
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

SIRB1_HUMAN
θ value	0.000461057 (rank : 1056)	NC score	0.121238 (rank : 1168)
Query Neighborhood Hits	2923	Target Neighborhood Hits	422	Shared Neighborhood Hits	191
SwissProt Accessions	O00241, Q5TFR0, Q8TB12, Q9H1U5, Q9Y4V0	Gene names	SIRPB1
Domain Architecture
Description	Signal-regulatory protein beta-1 precursor (SIRP-beta-1) (CD172b antigen).

SRPK2_HUMAN
θ value	0.000461057 (rank : 1057)	NC score	0.463829 (rank : 887)
Query Neighborhood Hits	2923	Target Neighborhood Hits	664	Shared Neighborhood Hits	600
SwissProt Accessions	P78362, O75220, O75221, Q6NUL0, Q6V1X2, Q8IYQ3	Gene names	SRPK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SRPK2 (EC 2.7.11.1) (Serine/arginine- rich protein-specific kinase 2) (SR-protein-specific kinase 2) (SFRS protein kinase 2).

SRPK2_MOUSE
θ value	0.000461057 (rank : 1058)	NC score	0.465553 (rank : 884)
Query Neighborhood Hits	2923	Target Neighborhood Hits	765	Shared Neighborhood Hits	664
SwissProt Accessions	O54781, Q8VCD9	Gene names	Srpk2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SRPK2 (EC 2.7.11.1) (Serine/arginine- rich protein-specific kinase 2) (SR-protein-specific kinase 2) (SFRS protein kinase 2).

TRDN_HUMAN
θ value	0.000461057 (rank : 1059)	NC score	0.093154 (rank : 1226)
Query Neighborhood Hits	2923	Target Neighborhood Hits	542	Shared Neighborhood Hits	306
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

UNC5A_HUMAN
θ value	0.000461057 (rank : 1060)	NC score	0.164245 (rank : 1120)
Query Neighborhood Hits	2923	Target Neighborhood Hits	198	Shared Neighborhood Hits	132
SwissProt Accessions	Q6ZN44, Q8TF26, Q96GP4	Gene names	UNC5A, KIAA1976, UNC5H1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

BT1A1_MOUSE
θ value	0.000602161 (rank : 1061)	NC score	0.080927 (rank : 1259)
Query Neighborhood Hits	2923	Target Neighborhood Hits	252	Shared Neighborhood Hits	170
SwissProt Accessions	Q62556, P97392, Q8K2H7, Q921K7	Gene names	Btn1a1, Btn
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

CD248_HUMAN
θ value	0.000602161 (rank : 1062)	NC score	0.032730 (rank : 1977)
Query Neighborhood Hits	2923	Target Neighborhood Hits	679	Shared Neighborhood Hits	193
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

FCG3A_HUMAN
θ value	0.000602161 (rank : 1063)	NC score	0.104552 (rank : 1200)
Query Neighborhood Hits	2923	Target Neighborhood Hits	65	Shared Neighborhood Hits	64
SwissProt Accessions	P08637	Gene names	FCGR3A, CD16A, FCG3, FCGR3, IGFR3
Domain Architecture
Description	Low affinity immunoglobulin gamma Fc region receptor III-A precursor (IgG Fc receptor III-2) (Fc-gamma RIII-alpha) (Fc-gamma RIIIa) (FcRIIIa) (Fc-gamma RIII) (FcRIII) (FcR-10) (CD16a antigen).

FCG3B_HUMAN
θ value	0.000602161 (rank : 1064)	NC score	0.112842 (rank : 1177)
Query Neighborhood Hits	2923	Target Neighborhood Hits	67	Shared Neighborhood Hits	66
SwissProt Accessions	O75015	Gene names	FCGR3B, CD16B, FCG3, FCGR3, IGFR3
Domain Architecture
Description	Low affinity immunoglobulin gamma Fc region receptor III-B precursor (IgG Fc receptor III-1) (Fc-gamma RIII-beta) (Fc-gamma RIIIb) (FcRIIIb) (Fc-gamma RIII) (FcRIII) (FcR-10) (CD16b antigen).

IL1R1_MOUSE
θ value	0.000602161 (rank : 1065)	NC score	0.181196 (rank : 1103)
Query Neighborhood Hits	2923	Target Neighborhood Hits	142	Shared Neighborhood Hits	133
SwissProt Accessions	P13504	Gene names	Il1r1, Il-1r1, Il1ra
Domain Architecture
Description	Interleukin-1 receptor type I precursor (IL-1R-1) (p80) (CD121a antigen).

MYO15_MOUSE
θ value	0.000602161 (rank : 1066)	NC score	0.038165 (rank : 1873)
Query Neighborhood Hits	2923	Target Neighborhood Hits	467	Shared Neighborhood Hits	183
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

PIGR_HUMAN
θ value	0.000602161 (rank : 1067)	NC score	0.179575 (rank : 1105)
Query Neighborhood Hits	2923	Target Neighborhood Hits	164	Shared Neighborhood Hits	135
SwissProt Accessions	P01833, Q8IZY7	Gene names	PIGR
Domain Architecture
Description	Polymeric-immunoglobulin receptor precursor (Poly-Ig receptor) (PIGR) (Hepatocellular carcinoma-associated protein TB6) [Contains: Secretory component].

PRG4_MOUSE
θ value	0.000602161 (rank : 1068)	NC score	0.110646 (rank : 1181)
Query Neighborhood Hits	2923	Target Neighborhood Hits	624	Shared Neighborhood Hits	323
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SIGL7_HUMAN
θ value	0.000602161 (rank : 1069)	NC score	0.201278 (rank : 1080)
Query Neighborhood Hits	2923	Target Neighborhood Hits	180	Shared Neighborhood Hits	166
SwissProt Accessions	Q9Y286, Q9NZQ1, Q9UJ86, Q9UJ87, Q9Y502	Gene names	SIGLEC7, AIRM1
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 7 precursor (Siglec-7) (QA79 membrane protein) (Adhesion inhibitory receptor molecule 1) (AIRM-1) (p75) (D-siglec) (CDw328 antigen).

TSC1_HUMAN
θ value	0.000602161 (rank : 1070)	NC score	0.068320 (rank : 1319)
Query Neighborhood Hits	2923	Target Neighborhood Hits	765	Shared Neighborhood Hits	332
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

CEAM7_HUMAN
θ value	0.000786445 (rank : 1071)	NC score	0.207693 (rank : 1068)
Query Neighborhood Hits	2923	Target Neighborhood Hits	170	Shared Neighborhood Hits	163
SwissProt Accessions	Q14002, O15148, O15149, Q13983, Q9UPJ2	Gene names	CEACAM7, CGM2
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 7 precursor (Carcinoembryonic antigen CGM2).

E2AK2_HUMAN
θ value	0.000786445 (rank : 1072)	NC score	0.691840 (rank : 380)
Query Neighborhood Hits	2923	Target Neighborhood Hits	856	Shared Neighborhood Hits	782
SwissProt Accessions	P19525	Gene names	EIF2AK2, PKR, PRKR
Domain Architecture
Description	Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Interferon-inducible RNA-dependent protein kinase) (Protein kinase RNA-activated) (PKR) (p68 kinase) (P1/eIF-2A protein kinase).

IGHG4_HUMAN
θ value	0.000786445 (rank : 1073)	NC score	0.041897 (rank : 1817)
Query Neighborhood Hits	2923	Target Neighborhood Hits	223	Shared Neighborhood Hits	69
SwissProt Accessions	P01861	Gene names	IGHG4
Domain Architecture
Description	Ig gamma-4 chain C region.

IGSF2_HUMAN
θ value	0.000786445 (rank : 1074)	NC score	0.118471 (rank : 1172)
Query Neighborhood Hits	2923	Target Neighborhood Hits	208	Shared Neighborhood Hits	138
SwissProt Accessions	Q93033, Q15856	Gene names	IGSF2, CD101, EWI101, V7
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 2 precursor (Glu-Trp-Ile EWI motif- containing protein 101) (EWI-101) (Cell surface glycoprotein V7) (CD101 antigen).

IWS1_HUMAN
θ value	0.000786445 (rank : 1075)	NC score	0.057618 (rank : 1503)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1241	Shared Neighborhood Hits	438
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

LRRK2_MOUSE
θ value	0.000786445 (rank : 1076)	NC score	0.576806 (rank : 691)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1359	Shared Neighborhood Hits	826
SwissProt Accessions	Q5S006, Q8BWG7, Q8BZJ6, Q8CI84, Q8K062	Gene names	Lrrk2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1).

SIGL5_HUMAN
θ value	0.000786445 (rank : 1077)	NC score	0.266754 (rank : 1023)
Query Neighborhood Hits	2923	Target Neighborhood Hits	246	Shared Neighborhood Hits	219
SwissProt Accessions	O15389	Gene names	SIGLEC5, CD33L2, OBBP2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 5 precursor (Siglec-5) (Obesity- binding protein 2) (OB-binding protein 2) (OB-BP2) (CD33 antigen-like 2) (CD170 antigen).

UNC5C_MOUSE
θ value	0.000786445 (rank : 1078)	NC score	0.161630 (rank : 1124)
Query Neighborhood Hits	2923	Target Neighborhood Hits	225	Shared Neighborhood Hits	148
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

CEL_HUMAN
θ value	0.00102713 (rank : 1079)	NC score	0.023362 (rank : 2139)
Query Neighborhood Hits	2923	Target Neighborhood Hits	896	Shared Neighborhood Hits	271
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

IBP7_HUMAN
θ value	0.00102713 (rank : 1080)	NC score	0.302358 (rank : 999)
Query Neighborhood Hits	2923	Target Neighborhood Hits	220	Shared Neighborhood Hits	168
SwissProt Accessions	Q16270, Q07822	Gene names	IGFBP7, MAC25, PSF
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein) (Prostacyclin-stimulating factor) (PGI2-stimulating factor) (IGFBP-rP1).

IL1AP_HUMAN
θ value	0.00102713 (rank : 1081)	NC score	0.076686 (rank : 1275)
Query Neighborhood Hits	2923	Target Neighborhood Hits	85	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NPH3, O14915, Q86WJ7	Gene names	IL1RAP
Domain Architecture
Description	Interleukin-1 receptor accessory protein precursor (IL-1 receptor accessory protein) (IL-1RAcP).

IRAK3_MOUSE
θ value	0.00102713 (rank : 1082)	NC score	0.494321 (rank : 849)
Query Neighborhood Hits	2923	Target Neighborhood Hits	628	Shared Neighborhood Hits	563
SwissProt Accessions	Q8K4B2, Q8C7U8, Q8CE40, Q8K1S8	Gene names	Irak3
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1) (IRAK-3) (IL- 1 receptor-associated kinase M) (IRAK-M).

LR37A_HUMAN
θ value	0.00102713 (rank : 1083)	NC score	0.074096 (rank : 1284)
Query Neighborhood Hits	2923	Target Neighborhood Hits	720	Shared Neighborhood Hits	286
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

MINT_MOUSE
θ value	0.00102713 (rank : 1084)	NC score	0.072825 (rank : 1293)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1514	Shared Neighborhood Hits	572
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NFM_MOUSE
θ value	0.00102713 (rank : 1085)	NC score	0.045525 (rank : 1758)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1159	Shared Neighborhood Hits	478
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

NRBP_HUMAN
θ value	0.00102713 (rank : 1086)	NC score	0.384249 (rank : 953)
Query Neighborhood Hits	2923	Target Neighborhood Hits	448	Shared Neighborhood Hits	406
SwissProt Accessions	Q9UHY1, Q53FZ5, Q96SU3	Gene names	NRBP1, BCON3, NRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor-binding protein.

NRBP_MOUSE
θ value	0.00102713 (rank : 1087)	NC score	0.382601 (rank : 958)
Query Neighborhood Hits	2923	Target Neighborhood Hits	442	Shared Neighborhood Hits	405
SwissProt Accessions	Q99J45, Q8BL77	Gene names	Nrbp1, Madm, Nrbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor-binding protein (MLF1 adapter molecule) (HLS7- interacting protein kinase).

NTKL_MOUSE
θ value	0.00102713 (rank : 1088)	NC score	0.297749 (rank : 1003)
Query Neighborhood Hits	2923	Target Neighborhood Hits	326	Shared Neighborhood Hits	293
SwissProt Accessions	Q9EQC5, Q3TST7, Q3UKU0, Q8K222	Gene names	Scyl1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like protein (SCY1-like protein 1) (105 kDa kinase- like protein) (Mitosis-associated kinase-like protein NTKL).

PDL1_MOUSE
θ value	0.00102713 (rank : 1089)	NC score	0.176062 (rank : 1108)
Query Neighborhood Hits	2923	Target Neighborhood Hits	168	Shared Neighborhood Hits	153
SwissProt Accessions	Q9EP73	Gene names	Cd274, B7h1, Pdcd1l1, Pdcd1lg1, Pdl1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

PGFRL_MOUSE
θ value	0.00102713 (rank : 1090)	NC score	0.190734 (rank : 1094)
Query Neighborhood Hits	2923	Target Neighborhood Hits	106	Shared Neighborhood Hits	100
SwissProt Accessions	Q6PE55, Q3V182, Q9D0Z1	Gene names	Pdgfrl
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor receptor-like protein precursor.

PTPRG_HUMAN
θ value	0.00102713 (rank : 1091)	NC score	0.058673 (rank : 1477)
Query Neighborhood Hits	2923	Target Neighborhood Hits	231	Shared Neighborhood Hits	98
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

BCL6_MOUSE
θ value	0.00134147 (rank : 1092)	NC score	-0.027155 (rank : 3095)
Query Neighborhood Hits	2923	Target Neighborhood Hits	913	Shared Neighborhood Hits	126
SwissProt Accessions	P41183, Q61065	Gene names	Bcl6, Bcl-6
Domain Architecture
Description	B-cell lymphoma 6 protein homolog.

HCFC1_MOUSE
θ value	0.00134147 (rank : 1093)	NC score	0.090525 (rank : 1231)
Query Neighborhood Hits	2923	Target Neighborhood Hits	348	Shared Neighborhood Hits	172
SwissProt Accessions	Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2	Gene names	Hcfc1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

IGHG1_HUMAN
θ value	0.00134147 (rank : 1094)	NC score	0.042711 (rank : 1799)
Query Neighborhood Hits	2923	Target Neighborhood Hits	229	Shared Neighborhood Hits	71
SwissProt Accessions	P01857	Gene names	IGHG1
Domain Architecture
Description	Ig gamma-1 chain C region.

OBF1_HUMAN
θ value	0.00134147 (rank : 1095)	NC score	0.039911 (rank : 1845)
Query Neighborhood Hits	2923	Target Neighborhood Hits	203	Shared Neighborhood Hits	81
SwissProt Accessions	Q16633, Q14983	Gene names	POU2AF1, OBF1
Domain Architecture	No domain graphic available
Description	POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (OCT-binding factor 1) (BOB-1) (OCA-B).

PVRL2_MOUSE
θ value	0.00134147 (rank : 1096)	NC score	0.198230 (rank : 1083)
Query Neighborhood Hits	2923	Target Neighborhood Hits	242	Shared Neighborhood Hits	166
SwissProt Accessions	P32507, Q62096	Gene names	Pvrl2, Mph, Pvr, Pvs
Domain Architecture
Description	Poliovirus receptor-related protein 2 precursor (Murine herpesvirus entry protein B) (mHveB) (Nectin-2) (Poliovirus receptor homolog) (CD112 antigen).

UNC5B_HUMAN
θ value	0.00134147 (rank : 1097)	NC score	0.153968 (rank : 1133)
Query Neighborhood Hits	2923	Target Neighborhood Hits	225	Shared Neighborhood Hits	147
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

UNC5B_MOUSE
θ value	0.00134147 (rank : 1098)	NC score	0.151471 (rank : 1136)
Query Neighborhood Hits	2923	Target Neighborhood Hits	226	Shared Neighborhood Hits	145
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

AL2S4_MOUSE
θ value	0.00175202 (rank : 1099)	NC score	0.040869 (rank : 1831)
Query Neighborhood Hits	2923	Target Neighborhood Hits	193	Shared Neighborhood Hits	79
SwissProt Accessions	Q3V0J1, Q3TIS2	Gene names	Als2cr4
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein homolog.

ASPP1_MOUSE
θ value	0.00175202 (rank : 1100)	NC score	0.051436 (rank : 1673)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1244	Shared Neighborhood Hits	459
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

CKAP4_MOUSE
θ value	0.00175202 (rank : 1101)	NC score	0.056707 (rank : 1540)
Query Neighborhood Hits	2923	Target Neighborhood Hits	596	Shared Neighborhood Hits	253
SwissProt Accessions	Q8BMK4, Q8BTK8, Q8R3F2	Gene names	Ckap4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

HHLA2_HUMAN
θ value	0.00175202 (rank : 1102)	NC score	0.155925 (rank : 1131)
Query Neighborhood Hits	2923	Target Neighborhood Hits	140	Shared Neighborhood Hits	119
SwissProt Accessions	Q9UM44, Q9NWQ6	Gene names	HHLA2
Domain Architecture	No domain graphic available
Description	HERV-H LTR-associating protein 2 precursor (Human endogenous retrovirus-H long terminal repeat-associating protein 2).

IL27B_HUMAN
θ value	0.00175202 (rank : 1103)	NC score	0.119920 (rank : 1171)
Query Neighborhood Hits	2923	Target Neighborhood Hits	80	Shared Neighborhood Hits	76
SwissProt Accessions	Q14213, O75269	Gene names	EBI3, IL27B
Domain Architecture
Description	Interleukin-27 beta chain precursor (IL-27B) (Epstein-Barr virus- induced gene 3 protein) (EBV-induced gene 3 protein).

LRC24_HUMAN
θ value	0.00175202 (rank : 1104)	NC score	0.171852 (rank : 1111)
Query Neighborhood Hits	2923	Target Neighborhood Hits	404	Shared Neighborhood Hits	214
SwissProt Accessions	Q50LG9	Gene names	LRRC24
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 24 precursor.

MAP1B_HUMAN
θ value	0.00175202 (rank : 1105)	NC score	0.092441 (rank : 1228)
Query Neighborhood Hits	2923	Target Neighborhood Hits	903	Shared Neighborhood Hits	433
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

PDL2_MOUSE
θ value	0.00175202 (rank : 1106)	NC score	0.171443 (rank : 1112)
Query Neighborhood Hits	2923	Target Neighborhood Hits	116	Shared Neighborhood Hits	110
SwissProt Accessions	Q9WUL5	Gene names	Pdcd1lg2, B7dc, Btdc, Cd273, Pdl2
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 2 precursor (Programmed death ligand 2) (PD-L2) (PD-1-ligand 2) (PDCD1 ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD273 antigen).

RIMB2_MOUSE
θ value	0.00175202 (rank : 1107)	NC score	0.094109 (rank : 1222)
Query Neighborhood Hits	2923	Target Neighborhood Hits	246	Shared Neighborhood Hits	115
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

SHPS1_MOUSE
θ value	0.00175202 (rank : 1108)	NC score	0.101177 (rank : 1202)
Query Neighborhood Hits	2923	Target Neighborhood Hits	439	Shared Neighborhood Hits	197
SwissProt Accessions	P97797, O08907, O35924, O88555, O88556, P97796, Q8R559, Q9QX57, Q9WTN4	Gene names	Sirpa, Bit, Myd1, Ptpns1, Shps1, Sirp
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type substrate 1 precursor (SHP substrate 1) (SHPS-1) (Inhibitory receptor SHPS-1) (Signal- regulatory protein alpha-1) (Sirp-alpha-1) (mSIRP-alpha1) (MyD-1 antigen) (Brain Ig-like molecule with tyrosine-based activation motifs) (Bit) (p84) (CD172a antigen).

TIMD4_MOUSE
θ value	0.00175202 (rank : 1109)	NC score	0.038284 (rank : 1871)
Query Neighborhood Hits	2923	Target Neighborhood Hits	65	Shared Neighborhood Hits	42
SwissProt Accessions	Q6U7R4, Q6U7R3, Q8CIC7	Gene names	Timd4, Tim4
Domain Architecture	No domain graphic available
Description	T-cell immunoglobulin and mucin domain-containing protein 4 precursor (TIMD-4) (T-cell membrane protein 4) (TIM-4) (Spleen, mucin- containing, knockout of lymphotoxin protein) (SMUCKLER).

TMM25_HUMAN
θ value	0.00175202 (rank : 1110)	NC score	0.086751 (rank : 1245)
Query Neighborhood Hits	2923	Target Neighborhood Hits	43	Shared Neighborhood Hits	41
SwissProt Accessions	Q86YD3, Q6UW89, Q86UA7, Q96KA6, Q96MW9	Gene names	TMEM25
Domain Architecture	No domain graphic available
Description	Transmembrane protein 25 precursor.

UNC5C_HUMAN
θ value	0.00175202 (rank : 1111)	NC score	0.160107 (rank : 1126)
Query Neighborhood Hits	2923	Target Neighborhood Hits	226	Shared Neighborhood Hits	143
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

BCAR1_HUMAN
θ value	0.00228821 (rank : 1112)	NC score	0.034920 (rank : 1931)
Query Neighborhood Hits	2923	Target Neighborhood Hits	554	Shared Neighborhood Hits	188
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

CO039_MOUSE
θ value	0.00228821 (rank : 1113)	NC score	0.049671 (rank : 1712)
Query Neighborhood Hits	2923	Target Neighborhood Hits	445	Shared Neighborhood Hits	196
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

I12R1_HUMAN
θ value	0.00228821 (rank : 1114)	NC score	0.107278 (rank : 1188)
Query Neighborhood Hits	2923	Target Neighborhood Hits	78	Shared Neighborhood Hits	68
SwissProt Accessions	P42701	Gene names	IL12RB1, IL12R, IL12RB
Domain Architecture
Description	Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) (IL- 12RB1) (CD212 antigen).

IBP7_MOUSE
θ value	0.00228821 (rank : 1115)	NC score	0.291945 (rank : 1008)
Query Neighborhood Hits	2923	Target Neighborhood Hits	230	Shared Neighborhood Hits	168
SwissProt Accessions	Q61581, O88812, Q9EQW0	Gene names	Igfbp7, Mac25
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).

KC1E_HUMAN
θ value	0.00228821 (rank : 1116)	NC score	0.549419 (rank : 758)
Query Neighborhood Hits	2923	Target Neighborhood Hits	732	Shared Neighborhood Hits	708
SwissProt Accessions	P49674	Gene names	CSNK1E
Domain Architecture
Description	Casein kinase I isoform epsilon (EC 2.7.11.1) (CKI-epsilon) (CKIe).

KC1E_MOUSE
θ value	0.00228821 (rank : 1117)	NC score	0.549412 (rank : 759)
Query Neighborhood Hits	2923	Target Neighborhood Hits	728	Shared Neighborhood Hits	708
SwissProt Accessions	Q9JMK2, Q8R389	Gene names	Csnk1e
Domain Architecture
Description	Casein kinase I isoform epsilon (EC 2.7.11.1) (CKI-epsilon) (CKIe).

KS6C1_HUMAN
θ value	0.00228821 (rank : 1118)	NC score	0.572920 (rank : 703)
Query Neighborhood Hits	2923	Target Neighborhood Hits	682	Shared Neighborhood Hits	633
SwissProt Accessions	Q96S38, Q8TDD3, Q9NSF4, Q9UL66	Gene names	RPS6KC1, RPK118
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase delta-1 (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase) (Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein) (SPHK1-binding protein).

LIFR_MOUSE
θ value	0.00228821 (rank : 1119)	NC score	0.191204 (rank : 1093)
Query Neighborhood Hits	2923	Target Neighborhood Hits	127	Shared Neighborhood Hits	108
SwissProt Accessions	P42703	Gene names	Lifr
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (D-factor/LIF receptor) (CD118 antigen).

LIMK2_MOUSE
θ value	0.00228821 (rank : 1120)	NC score	0.627234 (rank : 589)
Query Neighborhood Hits	2923	Target Neighborhood Hits	998	Shared Neighborhood Hits	781
SwissProt Accessions	O54785, O54776, O55238, Q9QUL4	Gene names	Limk2
Domain Architecture
Description	LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2).

PCLO_MOUSE
θ value	0.00228821 (rank : 1121)	NC score	0.089627 (rank : 1235)
Query Neighborhood Hits	2923	Target Neighborhood Hits	2275	Shared Neighborhood Hits	786
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

STAT2_MOUSE
θ value	0.00228821 (rank : 1122)	NC score	0.016816 (rank : 2268)
Query Neighborhood Hits	2923	Target Neighborhood Hits	175	Shared Neighborhood Hits	66
SwissProt Accessions	Q9WVL2, Q64188, Q64189, Q64250	Gene names	Stat2
Domain Architecture
Description	Signal transducer and activator of transcription 2.

STYK1_MOUSE
θ value	0.00228821 (rank : 1123)	NC score	0.557057 (rank : 730)
Query Neighborhood Hits	2923	Target Neighborhood Hits	779	Shared Neighborhood Hits	727
SwissProt Accessions	Q6J9G1, Q8BZH6, Q8BZT1	Gene names	Styk1, Nok
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (mNOK).

TACC2_HUMAN
θ value	0.00228821 (rank : 1124)	NC score	0.071807 (rank : 1298)
Query Neighborhood Hits	2923	Target Neighborhood Hits	856	Shared Neighborhood Hits	417
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

CT075_HUMAN
θ value	0.00298849 (rank : 1125)	NC score	0.121274 (rank : 1167)
Query Neighborhood Hits	2923	Target Neighborhood Hits	387	Shared Neighborhood Hits	159
SwissProt Accessions	Q8WUT4, Q5JWV6, Q9H419	Gene names	C20orf75
Domain Architecture
Description	Uncharacterized protein C20orf75 precursor.

K0319_MOUSE
θ value	0.00298849 (rank : 1126)	NC score	0.044342 (rank : 1771)
Query Neighborhood Hits	2923	Target Neighborhood Hits	134	Shared Neighborhood Hits	61
SwissProt Accessions	Q5SZV5, Q80U39	Gene names	Kiaa0319
Domain Architecture	No domain graphic available
Description	Protein KIAA0319 precursor.

LAG3_MOUSE
θ value	0.00298849 (rank : 1127)	NC score	0.157076 (rank : 1128)
Query Neighborhood Hits	2923	Target Neighborhood Hits	117	Shared Neighborhood Hits	104
SwissProt Accessions	Q61790, Q0VBL2	Gene names	Lag3
Domain Architecture
Description	Lymphocyte activation gene 3 protein precursor (LAG-3) (CD223 antigen).

LIMK2_HUMAN
θ value	0.00298849 (rank : 1128)	NC score	0.629596 (rank : 586)
Query Neighborhood Hits	2923	Target Neighborhood Hits	986	Shared Neighborhood Hits	778
SwissProt Accessions	P53671, Q7KZ80, Q96E10, Q99464	Gene names	LIMK2
Domain Architecture
Description	LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2).

PTPRG_MOUSE
θ value	0.00298849 (rank : 1129)	NC score	0.057046 (rank : 1527)
Query Neighborhood Hits	2923	Target Neighborhood Hits	260	Shared Neighborhood Hits	108
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRU_HUMAN
θ value	0.00298849 (rank : 1130)	NC score	0.159438 (rank : 1127)
Query Neighborhood Hits	2923	Target Neighborhood Hits	237	Shared Neighborhood Hits	172
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

SAFB2_HUMAN
θ value	0.00298849 (rank : 1131)	NC score	0.047517 (rank : 1734)
Query Neighborhood Hits	2923	Target Neighborhood Hits	720	Shared Neighborhood Hits	303
SwissProt Accessions	Q14151, Q8TB13	Gene names	SAFB2, KIAA0138
Domain Architecture
Description	Scaffold attachment factor B2.

TGON2_HUMAN
θ value	0.00298849 (rank : 1132)	NC score	0.069826 (rank : 1308)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1037	Shared Neighborhood Hits	351
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TPSNR_MOUSE
θ value	0.00298849 (rank : 1133)	NC score	0.104626 (rank : 1199)
Query Neighborhood Hits	2923	Target Neighborhood Hits	336	Shared Neighborhood Hits	173
SwissProt Accessions	Q8VD31	Gene names	Tapbpl
Domain Architecture	No domain graphic available
Description	Tapasin-related protein precursor (TAPASIN-R) (Tapasin-like) (TAP- binding protein-related protein) (TAPBP-R) (TAP-binding protein-like).

ZAN_HUMAN
θ value	0.00298849 (rank : 1134)	NC score	0.058277 (rank : 1486)
Query Neighborhood Hits	2923	Target Neighborhood Hits	679	Shared Neighborhood Hits	221
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

ALMS1_HUMAN
θ value	0.00390308 (rank : 1135)	NC score	0.040908 (rank : 1830)
Query Neighborhood Hits	2923	Target Neighborhood Hits	356	Shared Neighborhood Hits	149
SwissProt Accessions	Q8TCU4, Q53S05, Q580Q8, Q86VP9, Q9Y4G4	Gene names	ALMS1, KIAA0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1.

BPTF_HUMAN
θ value	0.00390308 (rank : 1136)	NC score	0.050471 (rank : 1695)
Query Neighborhood Hits	2923	Target Neighborhood Hits	786	Shared Neighborhood Hits	343
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

FANK1_MOUSE
θ value	0.00390308 (rank : 1137)	NC score	0.027907 (rank : 2049)
Query Neighborhood Hits	2923	Target Neighborhood Hits	325	Shared Neighborhood Hits	82
SwissProt Accessions	Q9DAM9, Q9CUA7	Gene names	Fank1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains 1 protein (Germ cell- specific gene 1 protein) (GSG1).

IWS1_MOUSE
θ value	0.00390308 (rank : 1138)	NC score	0.054466 (rank : 1590)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1258	Shared Neighborhood Hits	423
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

KS6C1_MOUSE
θ value	0.00390308 (rank : 1139)	NC score	0.576650 (rank : 693)
Query Neighborhood Hits	2923	Target Neighborhood Hits	700	Shared Neighborhood Hits	636
SwissProt Accessions	Q8BLK9, Q3UDY3, Q6PDY4, Q8BMQ5, Q8BX49	Gene names	Rps6kc1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase delta-1 (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase).

LCP2_HUMAN
θ value	0.00390308 (rank : 1140)	NC score	0.060751 (rank : 1421)
Query Neighborhood Hits	2923	Target Neighborhood Hits	531	Shared Neighborhood Hits	215
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

PRLR_MOUSE
θ value	0.00390308 (rank : 1141)	NC score	0.058921 (rank : 1470)
Query Neighborhood Hits	2923	Target Neighborhood Hits	82	Shared Neighborhood Hits	59
SwissProt Accessions	Q08501, P15212, P15213, Q62099	Gene names	Prlr
Domain Architecture
Description	Prolactin receptor precursor (PRL-R).

THOC2_HUMAN
θ value	0.00390308 (rank : 1142)	NC score	0.054825 (rank : 1582)
Query Neighborhood Hits	2923	Target Neighborhood Hits	337	Shared Neighborhood Hits	173
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

TRI18_MOUSE
θ value	0.00390308 (rank : 1143)	NC score	0.029937 (rank : 2002)
Query Neighborhood Hits	2923	Target Neighborhood Hits	292	Shared Neighborhood Hits	78
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

TTBK1_HUMAN
θ value	0.00390308 (rank : 1144)	NC score	0.575563 (rank : 695)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1058	Shared Neighborhood Hits	822
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

AKA12_HUMAN
θ value	0.00509761 (rank : 1145)	NC score	0.068263 (rank : 1320)
Query Neighborhood Hits	2923	Target Neighborhood Hits	825	Shared Neighborhood Hits	366
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

BTNL2_HUMAN
θ value	0.00509761 (rank : 1146)	NC score	0.120658 (rank : 1169)
Query Neighborhood Hits	2923	Target Neighborhood Hits	164	Shared Neighborhood Hits	144
SwissProt Accessions	Q9UIR0, O98261, Q5JYF9, Q5RIF8, Q5SP08, Q5SP09, Q5SRW3, Q5SRW4, Q5SU36, Q95HK0	Gene names	BTNL2
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 2 precursor (BTL-II).

GOGB1_HUMAN
θ value	0.00509761 (rank : 1147)	NC score	0.064535 (rank : 1348)
Query Neighborhood Hits	2923	Target Neighborhood Hits	2297	Shared Neighborhood Hits	668
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

I18RA_MOUSE
θ value	0.00509761 (rank : 1148)	NC score	0.088569 (rank : 1240)
Query Neighborhood Hits	2923	Target Neighborhood Hits	93	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Z2B1	Gene names	Il18rap
Domain Architecture	No domain graphic available
Description	Interleukin-18 receptor accessory protein precursor (IL-18 receptor accessory protein) (IL-18RAcP) (Interleukin-18 receptor accessory protein-like) (IL-18Rbeta) (IL-1R accessory protein-like) (IL-1RAcPL) (Accessory protein-like) (AcPL) (IL-1R7).

IGHG2_HUMAN
θ value	0.00509761 (rank : 1149)	NC score	0.035842 (rank : 1908)
Query Neighborhood Hits	2923	Target Neighborhood Hits	208	Shared Neighborhood Hits	60
SwissProt Accessions	P01859	Gene names	IGHG2
Domain Architecture
Description	Ig gamma-2 chain C region.

IGHG3_HUMAN
θ value	0.00509761 (rank : 1150)	NC score	0.043711 (rank : 1782)
Query Neighborhood Hits	2923	Target Neighborhood Hits	234	Shared Neighborhood Hits	79
SwissProt Accessions	P01860	Gene names	IGHG3
Domain Architecture
Description	Ig gamma-3 chain C region (Heavy chain disease protein) (HDC).

IL18R_MOUSE
θ value	0.00509761 (rank : 1151)	NC score	0.070952 (rank : 1303)
Query Neighborhood Hits	2923	Target Neighborhood Hits	82	Shared Neighborhood Hits	50
SwissProt Accessions	Q61098	Gene names	Il18r1
Domain Architecture
Description	Interleukin-18 receptor 1 precursor (IL1 receptor-related protein) (IL-1Rrp).

KC1D_HUMAN
θ value	0.00509761 (rank : 1152)	NC score	0.552657 (rank : 752)
Query Neighborhood Hits	2923	Target Neighborhood Hits	737	Shared Neighborhood Hits	713
SwissProt Accessions	P48730, Q96KZ6, Q9BTN5	Gene names	CSNK1D
Domain Architecture
Description	Casein kinase I isoform delta (EC 2.7.11.1) (CKI-delta) (CKId).

KC1D_MOUSE
θ value	0.00509761 (rank : 1153)	NC score	0.552674 (rank : 751)
Query Neighborhood Hits	2923	Target Neighborhood Hits	737	Shared Neighborhood Hits	713
SwissProt Accessions	Q9DC28, Q3TZK2, Q99KK4	Gene names	Csnk1d
Domain Architecture
Description	Casein kinase I isoform delta (EC 2.7.11.1) (CKI-delta) (CKId).

LRC24_MOUSE
θ value	0.00509761 (rank : 1154)	NC score	0.157034 (rank : 1129)
Query Neighborhood Hits	2923	Target Neighborhood Hits	387	Shared Neighborhood Hits	211
SwissProt Accessions	Q8BHA1	Gene names	Lrrc24
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 24 precursor.

LY9_MOUSE
θ value	0.00509761 (rank : 1155)	NC score	0.109645 (rank : 1184)
Query Neighborhood Hits	2923	Target Neighborhood Hits	110	Shared Neighborhood Hits	91
SwissProt Accessions	Q01965, Q9ES29, Q9ES35, Q9ES36	Gene names	Ly9, Ly-9
Domain Architecture
Description	T-lymphocyte surface antigen Ly-9 precursor (Lymphocyte antigen 9) (Cell-surface molecule Ly-9).

MAP4_MOUSE
θ value	0.00509761 (rank : 1156)	NC score	0.082120 (rank : 1256)
Query Neighborhood Hits	2923	Target Neighborhood Hits	409	Shared Neighborhood Hits	204
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

NTKL_HUMAN
θ value	0.00509761 (rank : 1157)	NC score	0.231568 (rank : 1044)
Query Neighborhood Hits	2923	Target Neighborhood Hits	266	Shared Neighborhood Hits	231
SwissProt Accessions	Q96KG9, Q96G50, Q96KG8, Q96KH1, Q9HAW5, Q9HBL3, Q9NR53	Gene names	SCYL1, GKLP, NTKL, TAPK, TEIF, TRAP
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like protein (SCY1-like protein 1) (Teratoma- associated tyrosine kinase) (Telomerase transcriptional element- interacting factor) (Telomerase regulation-associated protein).

PTPRV_MOUSE
θ value	0.00509761 (rank : 1158)	NC score	0.106353 (rank : 1190)
Query Neighborhood Hits	2923	Target Neighborhood Hits	179	Shared Neighborhood Hits	95
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

RIPK1_MOUSE
θ value	0.00509761 (rank : 1159)	NC score	0.638780 (rank : 574)
Query Neighborhood Hits	2923	Target Neighborhood Hits	874	Shared Neighborhood Hits	787
SwissProt Accessions	Q60855, Q3U0J3, Q8CD90	Gene names	Ripk1, Rinp, Rip
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

STK23_HUMAN
θ value	0.00509761 (rank : 1160)	NC score	0.460883 (rank : 889)
Query Neighborhood Hits	2923	Target Neighborhood Hits	556	Shared Neighborhood Hits	548
SwissProt Accessions	Q9UPE1, Q13583, Q9UM62	Gene names	STK23, MSSK1
Domain Architecture
Description	Serine/threonine-protein kinase 23 (EC 2.7.11.1) (Muscle-specific serine kinase 1) (MSSK-1).

STK23_MOUSE
θ value	0.00509761 (rank : 1161)	NC score	0.460821 (rank : 890)
Query Neighborhood Hits	2923	Target Neighborhood Hits	572	Shared Neighborhood Hits	555
SwissProt Accessions	Q9Z0G2	Gene names	Stk23, Mssk1
Domain Architecture
Description	Serine/threonine-protein kinase 23 (EC 2.7.11.1) (Muscle-specific serine kinase 1) (MSSK-1).

CO039_HUMAN
θ value	0.00665767 (rank : 1162)	NC score	0.048617 (rank : 1727)
Query Neighborhood Hits	2923	Target Neighborhood Hits	264	Shared Neighborhood Hits	119
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

FCRLA_HUMAN
θ value	0.00665767 (rank : 1163)	NC score	0.129410 (rank : 1158)
Query Neighborhood Hits	2923	Target Neighborhood Hits	135	Shared Neighborhood Hits	102
SwissProt Accessions	Q7L513, Q5VXA1, Q5VXA2, Q5VXA3, Q5VXB0, Q8NEW4, Q8WXH3, Q96PC6, Q96PJ0, Q96PJ1, Q96PJ2, Q96PJ4, Q9BR57	Gene names	FCRLA, FCRL, FCRL1, FCRLM1, FCRX, FREB
Domain Architecture	No domain graphic available
Description	Fc receptor-like and mucin-like 1 precursor (Fc receptor-like A) (Fc receptor homolog expressed in B-cells) (Fc receptor-related protein X) (FcRX) (Fc receptor-like protein).

FPRP_MOUSE
θ value	0.00665767 (rank : 1164)	NC score	0.101173 (rank : 1203)
Query Neighborhood Hits	2923	Target Neighborhood Hits	116	Shared Neighborhood Hits	95
SwissProt Accessions	Q9WV91	Gene names	Ptgfrn, Fprp
Domain Architecture
Description	Prostaglandin F2 receptor negative regulator precursor (Prostaglandin F2-alpha receptor regulatory protein) (Prostaglandin F2-alpha receptor-associated protein) (CD315 antigen).

HCFC1_HUMAN
θ value	0.00665767 (rank : 1165)	NC score	0.079141 (rank : 1267)
Query Neighborhood Hits	2923	Target Neighborhood Hits	331	Shared Neighborhood Hits	155
SwissProt Accessions	P51610, Q6P4G5	Gene names	HCFC1, HCF1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) (VP16 accessory protein) (VCAF) (CFF) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C- terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

I20RA_HUMAN
θ value	0.00665767 (rank : 1166)	NC score	0.023298 (rank : 2142)
Query Neighborhood Hits	2923	Target Neighborhood Hits	39	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UHF4, Q6UWA9, Q96SH8	Gene names	IL20RA, ZCYTOR7
Domain Architecture	No domain graphic available
Description	Interleukin-20 receptor alpha chain precursor (IL-20R-alpha) (IL-20R1) (Cytokine receptor family 2 member 8) (Cytokine receptor class-II member 8) (CRF2-8) (ZcytoR7).

IGH1M_MOUSE
θ value	0.00665767 (rank : 1167)	NC score	0.038299 (rank : 1870)
Query Neighborhood Hits	2923	Target Neighborhood Hits	223	Shared Neighborhood Hits	66
SwissProt Accessions	P01869	Gene names
Domain Architecture	No domain graphic available
Description	Ig gamma-1 chain C region, membrane-bound form.

IGHG1_MOUSE
θ value	0.00665767 (rank : 1168)	NC score	0.038386 (rank : 1866)
Query Neighborhood Hits	2923	Target Neighborhood Hits	219	Shared Neighborhood Hits	65
SwissProt Accessions	P01868	Gene names
Domain Architecture
Description	Ig gamma-1 chain C region secreted form.

MYH11_MOUSE
θ value	0.00665767 (rank : 1169)	NC score	0.057513 (rank : 1506)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1777	Shared Neighborhood Hits	565
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

PVRL1_HUMAN
θ value	0.00665767 (rank : 1170)	NC score	0.228840 (rank : 1049)
Query Neighborhood Hits	2923	Target Neighborhood Hits	219	Shared Neighborhood Hits	192
SwissProt Accessions	Q15223, O75465, Q9HBE6, Q9HBW2	Gene names	PVRL1, HVEC, PRR1
Domain Architecture
Description	Poliovirus receptor-related protein 1 precursor (Herpes virus entry mediator C) (HveC) (Nectin-1) (Herpesvirus Ig-like receptor) (HIgR) (CD111 antigen).

PVRL2_HUMAN
θ value	0.00665767 (rank : 1171)	NC score	0.184735 (rank : 1100)
Query Neighborhood Hits	2923	Target Neighborhood Hits	185	Shared Neighborhood Hits	148
SwissProt Accessions	Q92692, O75455, Q96J29	Gene names	PVRL2, HVEB, PRR2
Domain Architecture
Description	Poliovirus receptor-related protein 2 precursor (Herpes virus entry mediator B) (HveB) (Nectin-2) (CD112 antigen).

RADI_MOUSE
θ value	0.00665767 (rank : 1172)	NC score	0.044237 (rank : 1773)
Query Neighborhood Hits	2923	Target Neighborhood Hits	773	Shared Neighborhood Hits	329
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

REST_HUMAN
θ value	0.00665767 (rank : 1173)	NC score	0.061394 (rank : 1405)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1605	Shared Neighborhood Hits	539
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

SEM3C_MOUSE
θ value	0.00665767 (rank : 1174)	NC score	0.023794 (rank : 2130)
Query Neighborhood Hits	2923	Target Neighborhood Hits	113	Shared Neighborhood Hits	65
SwissProt Accessions	Q62181	Gene names	Sema3c, Semae, SemE
Domain Architecture
Description	Semaphorin-3C precursor (Semaphorin E) (Sema E).

AFF2_HUMAN
θ value	0.00869519 (rank : 1175)	NC score	0.033181 (rank : 1964)
Query Neighborhood Hits	2923	Target Neighborhood Hits	218	Shared Neighborhood Hits	107
SwissProt Accessions	P51816, O43786, O60215, P78407, Q13521, Q14323, Q9UNA5	Gene names	AFF2, FMR2, OX19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation 2 protein) (Protein FMR-2) (FMR2P) (Protein Ox19) (Fragile X E mental retardation syndrome protein).

BRD4_HUMAN
θ value	0.00869519 (rank : 1176)	NC score	0.062683 (rank : 1381)
Query Neighborhood Hits	2923	Target Neighborhood Hits	851	Shared Neighborhood Hits	448
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

CJ118_MOUSE
θ value	0.00869519 (rank : 1177)	NC score	0.061918 (rank : 1395)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1132	Shared Neighborhood Hits	427
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

ICAM1_MOUSE
θ value	0.00869519 (rank : 1178)	NC score	0.128951 (rank : 1159)
Query Neighborhood Hits	2923	Target Neighborhood Hits	99	Shared Neighborhood Hits	91
SwissProt Accessions	P13597, Q61828	Gene names	Icam1, Icam-1
Domain Architecture
Description	Intercellular adhesion molecule 1 precursor (ICAM-1) (MALA-2).

IL6RA_HUMAN
θ value	0.00869519 (rank : 1179)	NC score	0.082994 (rank : 1254)
Query Neighborhood Hits	2923	Target Neighborhood Hits	96	Shared Neighborhood Hits	82
SwissProt Accessions	P08887, Q16202, Q53EQ7, Q5FWG2, Q5VZ23	Gene names	IL6R
Domain Architecture
Description	Interleukin-6 receptor alpha chain precursor (IL-6R-alpha) (IL-6R 1) (Membrane glycoprotein 80) (gp80) (CD126 antigen).

LIRA4_HUMAN
θ value	0.00869519 (rank : 1180)	NC score	0.038830 (rank : 1861)
Query Neighborhood Hits	2923	Target Neighborhood Hits	92	Shared Neighborhood Hits	64
SwissProt Accessions	P59901	Gene names	LILRA4, ILT7
Domain Architecture
Description	Leukocyte immunoglobulin-like receptor subfamily A member 4 precursor (Immunoglobulin-like transcript 7) (ILT-7) (CD85g antigen).

LY9_HUMAN
θ value	0.00869519 (rank : 1181)	NC score	0.074877 (rank : 1281)
Query Neighborhood Hits	2923	Target Neighborhood Hits	82	Shared Neighborhood Hits	65
SwissProt Accessions	Q9HBG7, Q14775, Q5VYI3, Q9H4N5, Q9NQ24	Gene names	LY9
Domain Architecture
Description	T-lymphocyte surface antigen Ly-9 precursor (Lymphocyte antigen 9) (Cell-surface molecule Ly-9) (CD229 antigen).

MAP1B_MOUSE
θ value	0.00869519 (rank : 1182)	NC score	0.085360 (rank : 1247)
Query Neighborhood Hits	2923	Target Neighborhood Hits	977	Shared Neighborhood Hits	449
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

MINT_HUMAN
θ value	0.00869519 (rank : 1183)	NC score	0.077493 (rank : 1272)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1291	Shared Neighborhood Hits	521
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MLL3_MOUSE
θ value	0.00869519 (rank : 1184)	NC score	0.034719 (rank : 1935)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1399	Shared Neighborhood Hits	455
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MYO15_HUMAN
θ value	0.00869519 (rank : 1185)	NC score	0.039138 (rank : 1852)
Query Neighborhood Hits	2923	Target Neighborhood Hits	671	Shared Neighborhood Hits	254
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

PDL1_HUMAN
θ value	0.00869519 (rank : 1186)	NC score	0.204748 (rank : 1072)
Query Neighborhood Hits	2923	Target Neighborhood Hits	195	Shared Neighborhood Hits	175
SwissProt Accessions	Q9NZQ7, Q66RK1, Q6WEX4, Q9NUZ5	Gene names	CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

PLEC1_HUMAN
θ value	0.00869519 (rank : 1187)	NC score	0.051695 (rank : 1668)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1326	Shared Neighborhood Hits	463
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

RTN4_MOUSE
θ value	0.00869519 (rank : 1188)	NC score	0.045322 (rank : 1761)
Query Neighborhood Hits	2923	Target Neighborhood Hits	341	Shared Neighborhood Hits	176
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

RYK_HUMAN
θ value	0.00869519 (rank : 1189)	NC score	0.460527 (rank : 892)
Query Neighborhood Hits	2923	Target Neighborhood Hits	701	Shared Neighborhood Hits	652
SwissProt Accessions	P34925, Q04696	Gene names	RYK, JTK5A
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1).

SLAF6_HUMAN
θ value	0.00869519 (rank : 1190)	NC score	0.052272 (rank : 1654)
Query Neighborhood Hits	2923	Target Neighborhood Hits	62	Shared Neighborhood Hits	56
SwissProt Accessions	Q96DU3, Q5TAT3, Q96DV0	Gene names	SLAMF6, KALI
Domain Architecture	No domain graphic available
Description	SLAM family member 6 precursor (NK-T-B-antigen) (NTB-A) (Activating NK receptor).

SRRM1_MOUSE
θ value	0.00869519 (rank : 1191)	NC score	0.107266 (rank : 1189)
Query Neighborhood Hits	2923	Target Neighborhood Hits	966	Shared Neighborhood Hits	416
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

TAF3_MOUSE
θ value	0.00869519 (rank : 1192)	NC score	0.064273 (rank : 1351)
Query Neighborhood Hits	2923	Target Neighborhood Hits	463	Shared Neighborhood Hits	251
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TNI3K_MOUSE
θ value	0.00869519 (rank : 1193)	NC score	0.541182 (rank : 773)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1079	Shared Neighborhood Hits	765
SwissProt Accessions	Q5GIG6, Q5GIG5	Gene names	Tnni3k, Cark
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

TPR_HUMAN
θ value	0.00869519 (rank : 1194)	NC score	0.063854 (rank : 1361)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1921	Shared Neighborhood Hits	609
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

TRIM9_MOUSE
θ value	0.00869519 (rank : 1195)	NC score	0.057101 (rank : 1524)
Query Neighborhood Hits	2923	Target Neighborhood Hits	274	Shared Neighborhood Hits	87
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

CD244_MOUSE
θ value	0.0113563 (rank : 1196)	NC score	0.043393 (rank : 1787)
Query Neighborhood Hits	2923	Target Neighborhood Hits	38	Shared Neighborhood Hits	25
SwissProt Accessions	Q07763, O88654, Q9JIE0	Gene names	Cd244, 2b4, Nmrk
Domain Architecture
Description	Natural killer cell receptor 2B4 precursor (NKR2B4) (NK cell type I receptor protein 2B4) (CD244 antigen) (Non MHC restricted killing associated).

CT075_MOUSE
θ value	0.0113563 (rank : 1197)	NC score	0.096912 (rank : 1213)
Query Neighborhood Hits	2923	Target Neighborhood Hits	358	Shared Neighborhood Hits	137
SwissProt Accessions	P59383	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf75 homolog precursor.

ESCO1_HUMAN
θ value	0.0113563 (rank : 1198)	NC score	0.045426 (rank : 1760)
Query Neighborhood Hits	2923	Target Neighborhood Hits	361	Shared Neighborhood Hits	190
SwissProt Accessions	Q5FWF5, Q69YG4, Q69YS3, Q6IMD7, Q8N3Z5, Q8NBG2, Q96PX7	Gene names	ESCO1, EFO1, KIAA1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1) (Establishment factor- like protein 1) (EFO1p) (hEFO1) (CTF7 homolog 1).

FANK1_HUMAN
θ value	0.0113563 (rank : 1199)	NC score	0.027092 (rank : 2061)
Query Neighborhood Hits	2923	Target Neighborhood Hits	326	Shared Neighborhood Hits	77
SwissProt Accessions	Q8TC84, Q6UXY9, Q6X7T6	Gene names	FANK1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains protein 1.

FCGR2_MOUSE
θ value	0.0113563 (rank : 1200)	NC score	0.105955 (rank : 1192)
Query Neighborhood Hits	2923	Target Neighborhood Hits	105	Shared Neighborhood Hits	84
SwissProt Accessions	P08101, P08102, P12316, P97917, Q60938, Q60939, Q60940, Q61170, Q61558	Gene names	Fcgr2, Fcgr2b, Ly-17
Domain Architecture
Description	Low affinity immunoglobulin gamma Fc region receptor II precursor (Fc- gamma RII) (FcRII) (IgG Fc receptor II beta) (Fc gamma receptor IIB) (Fc-gamma-RIIB) (Lymphocyte antigen Ly-17) (CD32 antigen).

IGS21_HUMAN
θ value	0.0113563 (rank : 1201)	NC score	0.172017 (rank : 1110)
Query Neighborhood Hits	2923	Target Neighborhood Hits	123	Shared Neighborhood Hits	118
SwissProt Accessions	Q96ID5, Q8NBR8	Gene names	IGSF21
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 21 precursor.

IGS21_MOUSE
θ value	0.0113563 (rank : 1202)	NC score	0.171421 (rank : 1113)
Query Neighborhood Hits	2923	Target Neighborhood Hits	118	Shared Neighborhood Hits	113
SwissProt Accessions	Q7TNR6	Gene names	Igsf21
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 21 precursor.

KI67_HUMAN
θ value	0.0113563 (rank : 1203)	NC score	0.071044 (rank : 1302)
Query Neighborhood Hits	2923	Target Neighborhood Hits	581	Shared Neighborhood Hits	282
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

MUC_MOUSE
θ value	0.0113563 (rank : 1204)	NC score	0.059434 (rank : 1458)
Query Neighborhood Hits	2923	Target Neighborhood Hits	242	Shared Neighborhood Hits	90
SwissProt Accessions	P01872	Gene names
Domain Architecture	No domain graphic available
Description	Ig mu chain C region secreted form.

PAPOG_MOUSE
θ value	0.0113563 (rank : 1205)	NC score	0.014042 (rank : 2357)
Query Neighborhood Hits	2923	Target Neighborhood Hits	103	Shared Neighborhood Hits	46
SwissProt Accessions	Q6PCL9, Q8BZC9	Gene names	Papolg
Domain Architecture	No domain graphic available
Description	Poly(A) polymerase gamma (EC 2.7.7.19) (PAP gamma) (Polynucleotide adenylyltransferase gamma) (SRP RNA 3' adenylating enzyme).

PLCB4_HUMAN
θ value	0.0113563 (rank : 1206)	NC score	0.057268 (rank : 1516)
Query Neighborhood Hits	2923	Target Neighborhood Hits	658	Shared Neighborhood Hits	326
SwissProt Accessions	Q15147, Q5JYS8, Q5JYT0, Q5JYT4, Q9BQW5, Q9BQW6, Q9BQW8, Q9UJQ2	Gene names	PLCB4
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-4) (PLC-beta-4).

PTPRO_HUMAN
θ value	0.0113563 (rank : 1207)	NC score	0.082865 (rank : 1255)
Query Neighborhood Hits	2923	Target Neighborhood Hits	139	Shared Neighborhood Hits	75
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

SIRPG_HUMAN
θ value	0.0113563 (rank : 1208)	NC score	0.097321 (rank : 1210)
Query Neighborhood Hits	2923	Target Neighborhood Hits	359	Shared Neighborhood Hits	153
SwissProt Accessions	Q9P1W8, Q8WWA5, Q9NQK8	Gene names	SIRPG, SIRPB2
Domain Architecture
Description	Signal-regulatory protein gamma precursor (Signal-regulatory protein beta-2) (SIRP-beta-2) (SIRP-b2) (CD172g antigen).

TMM25_MOUSE
θ value	0.0113563 (rank : 1209)	NC score	0.086993 (rank : 1244)
Query Neighborhood Hits	2923	Target Neighborhood Hits	46	Shared Neighborhood Hits	45
SwissProt Accessions	Q9DCF1, Q3TMP3, Q6PAK7	Gene names	Tmem25
Domain Architecture	No domain graphic available
Description	Transmembrane protein 25 precursor.

AMPH_HUMAN
θ value	0.0148317 (rank : 1210)	NC score	0.046661 (rank : 1743)
Query Neighborhood Hits	2923	Target Neighborhood Hits	455	Shared Neighborhood Hits	204
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

C102B_HUMAN
θ value	0.0148317 (rank : 1211)	NC score	0.055333 (rank : 1570)
Query Neighborhood Hits	2923	Target Neighborhood Hits	542	Shared Neighborhood Hits	257
SwissProt Accessions	Q68D86, Q7Z467, Q8NDK7, Q9H5C1	Gene names	CCDC102B, C18orf14
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 102B.

CASZ1_HUMAN
θ value	0.0148317 (rank : 1212)	NC score	0.005514 (rank : 2609)
Query Neighborhood Hits	2923	Target Neighborhood Hits	473	Shared Neighborhood Hits	68
SwissProt Accessions	Q86V15, Q5T9S1, Q8WX49, Q8WX50, Q9BT16, Q9NXC6	Gene names	CASZ1, CST, ZNF693
Domain Architecture	No domain graphic available
Description	Castor homolog 1 zinc finger protein (Castor-related protein) (Zinc finger protein 693).

CCD12_HUMAN
θ value	0.0148317 (rank : 1213)	NC score	0.034054 (rank : 1947)
Query Neighborhood Hits	2923	Target Neighborhood Hits	39	Shared Neighborhood Hits	19
SwissProt Accessions	Q8WUD4, Q8N8I4	Gene names	CCDC12
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 12.

CD3E_MOUSE
θ value	0.0148317 (rank : 1214)	NC score	0.056172 (rank : 1551)
Query Neighborhood Hits	2923	Target Neighborhood Hits	34	Shared Neighborhood Hits	24
SwissProt Accessions	P22646	Gene names	Cd3e
Domain Architecture
Description	T-cell surface glycoprotein CD3 epsilon chain precursor (T-cell surface antigen T3/Leu-4 epsilon chain).

CSF3R_MOUSE
θ value	0.0148317 (rank : 1215)	NC score	0.137630 (rank : 1152)
Query Neighborhood Hits	2923	Target Neighborhood Hits	104	Shared Neighborhood Hits	96
SwissProt Accessions	P40223	Gene names	Csf3r, Csfgr
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

GCBM_MOUSE
θ value	0.0148317 (rank : 1216)	NC score	0.035557 (rank : 1917)
Query Neighborhood Hits	2923	Target Neighborhood Hits	218	Shared Neighborhood Hits	65
SwissProt Accessions	P01867	Gene names
Domain Architecture
Description	Ig gamma-2B chain C region, membrane-bound form.

GCB_MOUSE
θ value	0.0148317 (rank : 1217)	NC score	0.035542 (rank : 1918)
Query Neighborhood Hits	2923	Target Neighborhood Hits	214	Shared Neighborhood Hits	63
SwissProt Accessions	P01866	Gene names
Domain Architecture	No domain graphic available
Description	Ig gamma-2B chain C region secreted form.

HS105_HUMAN
θ value	0.0148317 (rank : 1218)	NC score	0.018487 (rank : 2227)
Query Neighborhood Hits	2923	Target Neighborhood Hits	209	Shared Neighborhood Hits	115
SwissProt Accessions	Q92598, O95739, Q5TBM6, Q5TBM8, Q9UPC4	Gene names	HSPH1, HSP105, HSP110, KIAA0201
Domain Architecture
Description	Heat-shock protein 105 kDa (Heat shock 110 kDa protein) (Antigen NY- CO-25).

MOX2R_MOUSE
θ value	0.0148317 (rank : 1219)	NC score	0.191910 (rank : 1091)
Query Neighborhood Hits	2923	Target Neighborhood Hits	110	Shared Neighborhood Hits	107
SwissProt Accessions	Q9ES57	Gene names	Cd200r1, Mox2r, Ox2r
Domain Architecture	No domain graphic available
Description	Cell surface glycoprotein OX2 receptor precursor (CD200 cell surface glycoprotein receptor).

MUCM_MOUSE
θ value	0.0148317 (rank : 1220)	NC score	0.059253 (rank : 1464)
Query Neighborhood Hits	2923	Target Neighborhood Hits	242	Shared Neighborhood Hits	89
SwissProt Accessions	P01873	Gene names
Domain Architecture	No domain graphic available
Description	Ig mu chain C region membrane-bound form.

MYO5A_HUMAN
θ value	0.0148317 (rank : 1221)	NC score	0.056390 (rank : 1545)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1092	Shared Neighborhood Hits	433
SwissProt Accessions	Q9Y4I1, O60653, Q07902, Q16249, Q9UE30, Q9UE31	Gene names	MYO5A, MYH12
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin).

PRG4_HUMAN
θ value	0.0148317 (rank : 1222)	NC score	0.107542 (rank : 1186)
Query Neighborhood Hits	2923	Target Neighborhood Hits	764	Shared Neighborhood Hits	374
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRLR_HUMAN
θ value	0.0148317 (rank : 1223)	NC score	0.060366 (rank : 1429)
Query Neighborhood Hits	2923	Target Neighborhood Hits	95	Shared Neighborhood Hits	66
SwissProt Accessions	P16471, Q16354, Q9BX87	Gene names	PRLR
Domain Architecture
Description	Prolactin receptor precursor (PRL-R).

RIPK3_MOUSE
θ value	0.0148317 (rank : 1224)	NC score	0.619378 (rank : 602)
Query Neighborhood Hits	2923	Target Neighborhood Hits	867	Shared Neighborhood Hits	770
SwissProt Accessions	Q9QZL0	Gene names	Ripk3, Rip3
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (mRIP3).

SYCP1_MOUSE
θ value	0.0148317 (rank : 1225)	NC score	0.060217 (rank : 1435)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1456	Shared Neighborhood Hits	515
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

VRK3_HUMAN
θ value	0.0148317 (rank : 1226)	NC score	0.229347 (rank : 1048)
Query Neighborhood Hits	2923	Target Neighborhood Hits	349	Shared Neighborhood Hits	321
SwissProt Accessions	Q8IV63, Q9P2V8	Gene names	VRK3
Domain Architecture
Description	Serine/threonine-protein kinase VRK3 (EC 2.7.11.1) (Vaccinia-related kinase 3).

BCOR_HUMAN
θ value	0.0193708 (rank : 1227)	NC score	0.015447 (rank : 2305)
Query Neighborhood Hits	2923	Target Neighborhood Hits	609	Shared Neighborhood Hits	171
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

BT3A2_HUMAN
θ value	0.0193708 (rank : 1228)	NC score	0.096845 (rank : 1214)
Query Neighborhood Hits	2923	Target Neighborhood Hits	158	Shared Neighborhood Hits	134
SwissProt Accessions	P78410, O00477, O15338, O75658, Q76PA0, Q9BU81, Q9NR44	Gene names	BTN3A2, BT3.2, BTF3, BTF4
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A2 precursor.

BT3A3_HUMAN
θ value	0.0193708 (rank : 1229)	NC score	0.057766 (rank : 1498)
Query Neighborhood Hits	2923	Target Neighborhood Hits	233	Shared Neighborhood Hits	152
SwissProt Accessions	O00478	Gene names	BTN3A3, BTF3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A3 precursor.

CD79A_HUMAN
θ value	0.0193708 (rank : 1230)	NC score	0.122500 (rank : 1166)
Query Neighborhood Hits	2923	Target Neighborhood Hits	102	Shared Neighborhood Hits	82
SwissProt Accessions	P11912	Gene names	CD79A, IGA, MB1
Domain Architecture
Description	B-cell antigen receptor complex-associated protein alpha-chain precursor (Ig-alpha) (MB-1 membrane glycoprotein) (Surface IgM- associated protein) (Membrane-bound immunoglobulin-associated protein) (CD79a antigen).

CD7_MOUSE
θ value	0.0193708 (rank : 1231)	NC score	0.057157 (rank : 1521)
Query Neighborhood Hits	2923	Target Neighborhood Hits	142	Shared Neighborhood Hits	87
SwissProt Accessions	P50283	Gene names	Cd7
Domain Architecture
Description	T-cell antigen CD7 precursor.

EEA1_HUMAN
θ value	0.0193708 (rank : 1232)	NC score	0.056216 (rank : 1550)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1796	Shared Neighborhood Hits	558
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

GCAB_MOUSE
θ value	0.0193708 (rank : 1233)	NC score	0.033886 (rank : 1950)
Query Neighborhood Hits	2923	Target Neighborhood Hits	203	Shared Neighborhood Hits	57
SwissProt Accessions	P01864	Gene names
Domain Architecture	No domain graphic available
Description	Ig gamma-2A chain C region secreted form (B allele).

GCC2_MOUSE
θ value	0.0193708 (rank : 1234)	NC score	0.060751 (rank : 1420)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1619	Shared Neighborhood Hits	535
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

GNAS1_MOUSE
θ value	0.0193708 (rank : 1235)	NC score	0.016630 (rank : 2274)
Query Neighborhood Hits	2923	Target Neighborhood Hits	651	Shared Neighborhood Hits	201
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

HS74L_MOUSE
θ value	0.0193708 (rank : 1236)	NC score	0.016175 (rank : 2286)
Query Neighborhood Hits	2923	Target Neighborhood Hits	141	Shared Neighborhood Hits	68
SwissProt Accessions	P48722, P97854, Q8BQD0, Q8CC45, Q91X29	Gene names	Hspa4l, Apg1, Hsp4l, Osp94
Domain Architecture
Description	Heat shock 70 kDa protein 4L (Osmotic stress protein 94) (Heat shock 70-related protein APG-1).

K1543_HUMAN
θ value	0.0193708 (rank : 1237)	NC score	0.048750 (rank : 1721)
Query Neighborhood Hits	2923	Target Neighborhood Hits	435	Shared Neighborhood Hits	175
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

KIF17_HUMAN
θ value	0.0193708 (rank : 1238)	NC score	0.015350 (rank : 2309)
Query Neighborhood Hits	2923	Target Neighborhood Hits	365	Shared Neighborhood Hits	196
SwissProt Accessions	Q9P2E2, O95077, Q53YS6, Q5VWA9, Q6GSA8, Q8N411	Gene names	KIF17, KIAA1405, KIF3X
Domain Architecture
Description	Kinesin-like protein KIF17 (KIF3-related motor protein).

MYH14_MOUSE
θ value	0.0193708 (rank : 1239)	NC score	0.055783 (rank : 1561)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1225	Shared Neighborhood Hits	431
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

NCOA6_HUMAN
θ value	0.0193708 (rank : 1240)	NC score	0.057684 (rank : 1502)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1202	Shared Neighborhood Hits	413
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NOP56_HUMAN
θ value	0.0193708 (rank : 1241)	NC score	0.029394 (rank : 2017)
Query Neighborhood Hits	2923	Target Neighborhood Hits	95	Shared Neighborhood Hits	58
SwissProt Accessions	O00567, Q9NQ05	Gene names	NOL5A, NOP56
Domain Architecture
Description	Nucleolar protein Nop56 (Nucleolar protein 5A).

SMC2_HUMAN
θ value	0.0193708 (rank : 1242)	NC score	0.061859 (rank : 1397)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1405	Shared Neighborhood Hits	513
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

TRI36_MOUSE
θ value	0.0193708 (rank : 1243)	NC score	0.033471 (rank : 1960)
Query Neighborhood Hits	2923	Target Neighborhood Hits	266	Shared Neighborhood Hits	86
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

TRI46_HUMAN
θ value	0.0193708 (rank : 1244)	NC score	0.027904 (rank : 2050)
Query Neighborhood Hits	2923	Target Neighborhood Hits	291	Shared Neighborhood Hits	85
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI46_MOUSE
θ value	0.0193708 (rank : 1245)	NC score	0.028408 (rank : 2037)
Query Neighborhood Hits	2923	Target Neighborhood Hits	287	Shared Neighborhood Hits	85
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRIM9_HUMAN
θ value	0.0193708 (rank : 1246)	NC score	0.060036 (rank : 1439)
Query Neighborhood Hits	2923	Target Neighborhood Hits	294	Shared Neighborhood Hits	99
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

TRML1_MOUSE
θ value	0.0193708 (rank : 1247)	NC score	0.043942 (rank : 1780)
Query Neighborhood Hits	2923	Target Neighborhood Hits	44	Shared Neighborhood Hits	29
SwissProt Accessions	Q8K558, Q9D3N6	Gene names	Treml1, Tlt1
Domain Architecture	No domain graphic available
Description	Trem-like transcript 1 protein precursor (TLT-1) (Triggering receptor expressed on myeloid cells-like protein 1).

UACA_HUMAN
θ value	0.0193708 (rank : 1248)	NC score	0.048650 (rank : 1723)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1622	Shared Neighborhood Hits	469
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

YLPM1_HUMAN
θ value	0.0193708 (rank : 1249)	NC score	0.058841 (rank : 1473)
Query Neighborhood Hits	2923	Target Neighborhood Hits	670	Shared Neighborhood Hits	269
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

ZFP95_HUMAN
θ value	0.0193708 (rank : 1250)	NC score	-0.029075 (rank : 3107)
Query Neighborhood Hits	2923	Target Neighborhood Hits	775	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y2L8	Gene names	ZFP95, KIAA1015
Domain Architecture
Description	Zinc finger protein 95 homolog (Zfp-95).

BT1A1_HUMAN
θ value	0.0252991 (rank : 1251)	NC score	0.072624 (rank : 1294)
Query Neighborhood Hits	2923	Target Neighborhood Hits	322	Shared Neighborhood Hits	161
SwissProt Accessions	Q13410, Q9H458	Gene names	BTN1A1, BTN
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

HS74L_HUMAN
θ value	0.0252991 (rank : 1252)	NC score	0.018108 (rank : 2235)
Query Neighborhood Hits	2923	Target Neighborhood Hits	141	Shared Neighborhood Hits	82
SwissProt Accessions	O95757, Q4W5M5, Q8IWA2	Gene names	HSPA4L, APG1, OSP94
Domain Architecture
Description	Heat shock 70 kDa protein 4L (Osmotic stress protein 94) (Heat shock 70-related protein APG-1).

JAML1_MOUSE
θ value	0.0252991 (rank : 1253)	NC score	0.156881 (rank : 1130)
Query Neighborhood Hits	2923	Target Neighborhood Hits	185	Shared Neighborhood Hits	153
SwissProt Accessions	Q80UL9, Q5DTC4	Gene names	Amica1, Gm638, Jaml
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule-like precursor (mCrea7).

K0586_HUMAN
θ value	0.0252991 (rank : 1254)	NC score	0.066379 (rank : 1333)
Query Neighborhood Hits	2923	Target Neighborhood Hits	311	Shared Neighborhood Hits	182
SwissProt Accessions	Q9BVV6, O60328	Gene names	KIAA0586
Domain Architecture	No domain graphic available
Description	Protein KIAA0586.

KI13A_MOUSE
θ value	0.0252991 (rank : 1255)	NC score	0.015676 (rank : 2295)
Query Neighborhood Hits	2923	Target Neighborhood Hits	395	Shared Neighborhood Hits	202
SwissProt Accessions	Q9EQW7, O35062	Gene names	Kif13a
Domain Architecture
Description	Kinesin-like protein KIF13A.

KTN1_HUMAN
θ value	0.0252991 (rank : 1256)	NC score	0.058580 (rank : 1479)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1197	Shared Neighborhood Hits	425
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

RIPK1_HUMAN
θ value	0.0252991 (rank : 1257)	NC score	0.645740 (rank : 560)
Query Neighborhood Hits	2923	Target Neighborhood Hits	891	Shared Neighborhood Hits	798
SwissProt Accessions	Q13546, Q13180	Gene names	RIPK1, RIP
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

TRIPB_HUMAN
θ value	0.0252991 (rank : 1258)	NC score	0.062398 (rank : 1388)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1587	Shared Neighborhood Hits	525
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

TTBK2_HUMAN
θ value	0.0252991 (rank : 1259)	NC score	0.565721 (rank : 715)
Query Neighborhood Hits	2923	Target Neighborhood Hits	822	Shared Neighborhood Hits	740
SwissProt Accessions	Q6IQ55, O94932, Q6ZN52, Q8IVV1	Gene names	TTBK2, KIAA0847
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 2 (EC 2.7.11.1).

WDR76_HUMAN
θ value	0.0252991 (rank : 1260)	NC score	0.019692 (rank : 2211)
Query Neighborhood Hits	2923	Target Neighborhood Hits	73	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H967	Gene names	WDR76
Domain Architecture	No domain graphic available
Description	WD repeat protein 76.

APC_HUMAN
θ value	0.0330416 (rank : 1261)	NC score	0.042604 (rank : 1801)
Query Neighborhood Hits	2923	Target Neighborhood Hits	603	Shared Neighborhood Hits	275
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

BLNK_HUMAN
θ value	0.0330416 (rank : 1262)	NC score	0.051973 (rank : 1662)
Query Neighborhood Hits	2923	Target Neighborhood Hits	228	Shared Neighborhood Hits	107
SwissProt Accessions	Q8WV28, O75498, O75499	Gene names	BLNK, BASH, SLP65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (SLP-65).

BRD8_HUMAN
θ value	0.0330416 (rank : 1263)	NC score	0.019016 (rank : 2220)
Query Neighborhood Hits	2923	Target Neighborhood Hits	292	Shared Neighborhood Hits	104
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

CASL_HUMAN
θ value	0.0330416 (rank : 1264)	NC score	0.024143 (rank : 2127)
Query Neighborhood Hits	2923	Target Neighborhood Hits	259	Shared Neighborhood Hits	85
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

CRLF1_MOUSE
θ value	0.0330416 (rank : 1265)	NC score	0.105867 (rank : 1194)
Query Neighborhood Hits	2923	Target Neighborhood Hits	116	Shared Neighborhood Hits	98
SwissProt Accessions	Q9JM58	Gene names	Crlf1, Crlm3
Domain Architecture
Description	Cytokine receptor-like factor 1 precursor (Cytokine-like factor 1) (CLF-1) (Cytokine receptor-like molecule 3) (CRLM-3) (NR6).

GOGA1_HUMAN
θ value	0.0330416 (rank : 1266)	NC score	0.063136 (rank : 1372)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1222	Shared Neighborhood Hits	445
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

K1543_MOUSE
θ value	0.0330416 (rank : 1267)	NC score	0.045759 (rank : 1753)
Query Neighborhood Hits	2923	Target Neighborhood Hits	497	Shared Neighborhood Hits	204
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

LRBA_HUMAN
θ value	0.0330416 (rank : 1268)	NC score	0.007195 (rank : 2560)
Query Neighborhood Hits	2923	Target Neighborhood Hits	196	Shared Neighborhood Hits	41
SwissProt Accessions	P50851, Q9H2U3, Q9H2U4	Gene names	LRBA, BGL, CDC4L, LBA
Domain Architecture
Description	Lipopolysaccharide-responsive and beige-like anchor protein (CDC4-like protein) (Beige-like protein).

MBB1A_HUMAN
θ value	0.0330416 (rank : 1269)	NC score	0.054405 (rank : 1595)
Query Neighborhood Hits	2923	Target Neighborhood Hits	665	Shared Neighborhood Hits	269
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

MUC_HUMAN
θ value	0.0330416 (rank : 1270)	NC score	0.041758 (rank : 1818)
Query Neighborhood Hits	2923	Target Neighborhood Hits	231	Shared Neighborhood Hits	77
SwissProt Accessions	P01871	Gene names	IGHM
Domain Architecture
Description	Ig mu chain C region.

NIPBL_HUMAN
θ value	0.0330416 (rank : 1271)	NC score	0.062916 (rank : 1378)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1311	Shared Neighborhood Hits	512
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

PHF20_HUMAN
θ value	0.0330416 (rank : 1272)	NC score	0.035673 (rank : 1913)
Query Neighborhood Hits	2923	Target Neighborhood Hits	394	Shared Neighborhood Hits	176
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

PVRL1_MOUSE
θ value	0.0330416 (rank : 1273)	NC score	0.219652 (rank : 1060)
Query Neighborhood Hits	2923	Target Neighborhood Hits	201	Shared Neighborhood Hits	183
SwissProt Accessions	Q9JKF6, Q9ERL5, Q9JI17	Gene names	Pvrl1, Hvec, Prr1
Domain Architecture
Description	Poliovirus receptor-related protein 1 precursor (Herpes virus entry mediator C) (HveC) (Nectin-1) (CD111 antigen).

SAFB2_MOUSE
θ value	0.0330416 (rank : 1274)	NC score	0.041257 (rank : 1826)
Query Neighborhood Hits	2923	Target Neighborhood Hits	581	Shared Neighborhood Hits	253
SwissProt Accessions	Q80YR5, Q8K153	Gene names	Safb2
Domain Architecture
Description	Scaffold attachment factor B2.

SMC4_MOUSE
θ value	0.0330416 (rank : 1275)	NC score	0.048631 (rank : 1726)
Query Neighborhood Hits	2923	Target Neighborhood Hits	830	Shared Neighborhood Hits	334
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

SYUG_MOUSE
θ value	0.0330416 (rank : 1276)	NC score	0.021321 (rank : 2176)
Query Neighborhood Hits	2923	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z0F7	Gene names	Sncg, Persyn
Domain Architecture
Description	Gamma-synuclein (Persyn).

TTBK2_MOUSE
θ value	0.0330416 (rank : 1277)	NC score	0.561646 (rank : 721)
Query Neighborhood Hits	2923	Target Neighborhood Hits	811	Shared Neighborhood Hits	728
SwissProt Accessions	Q3UVR3, Q3TSR6, Q3UFW0, Q571D1, Q8BKA4, Q924U8	Gene names	Ttbk2, Kiaa0847, Ttbk1
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 2.

ZN645_HUMAN
θ value	0.0330416 (rank : 1278)	NC score	0.030719 (rank : 1998)
Query Neighborhood Hits	2923	Target Neighborhood Hits	265	Shared Neighborhood Hits	78
SwissProt Accessions	Q8N7E2, Q6DJY9	Gene names	ZNF645
Domain Architecture	No domain graphic available
Description	Zinc finger protein 645.

ATS19_HUMAN
θ value	0.0431538 (rank : 1279)	NC score	0.011667 (rank : 2421)
Query Neighborhood Hits	2923	Target Neighborhood Hits	203	Shared Neighborhood Hits	54
SwissProt Accessions	Q8TE59	Gene names	ADAMTS19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

BCL6_HUMAN
θ value	0.0431538 (rank : 1280)	NC score	-0.027759 (rank : 3098)
Query Neighborhood Hits	2923	Target Neighborhood Hits	922	Shared Neighborhood Hits	123
SwissProt Accessions	P41182	Gene names	BCL6, BCL5, LAZ3, ZBTB27, ZNF51
Domain Architecture
Description	B-cell lymphoma 6 protein (BCL-6) (Zinc finger protein 51) (LAZ-3 protein) (BCL-5) (Zinc finger and BTB domain-containing protein 27).

BT3A1_HUMAN
θ value	0.0431538 (rank : 1281)	NC score	0.056953 (rank : 1530)
Query Neighborhood Hits	2923	Target Neighborhood Hits	229	Shared Neighborhood Hits	150
SwissProt Accessions	O00481, Q99420, Q9HCY1	Gene names	BTN3A1, BTF5
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A1 precursor (CD277 antigen).

CCD21_HUMAN
θ value	0.0431538 (rank : 1282)	NC score	0.062161 (rank : 1391)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1228	Shared Neighborhood Hits	467
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CRLF1_HUMAN
θ value	0.0431538 (rank : 1283)	NC score	0.111136 (rank : 1179)
Query Neighborhood Hits	2923	Target Neighborhood Hits	122	Shared Neighborhood Hits	105
SwissProt Accessions	O75462, Q9UHH5	Gene names	CRLF1, ZCYTOR5
Domain Architecture
Description	Cytokine receptor-like factor 1 precursor (Cytokine-like factor 1) (CLF-1) (ZcytoR5).

GHR_HUMAN
θ value	0.0431538 (rank : 1284)	NC score	0.032133 (rank : 1981)
Query Neighborhood Hits	2923	Target Neighborhood Hits	57	Shared Neighborhood Hits	35
SwissProt Accessions	P10912, Q9HCX2	Gene names	GHR
Domain Architecture
Description	Growth hormone receptor precursor (GH receptor) (Somatotropin receptor) [Contains: Growth hormone-binding protein (GH-binding protein) (GHBP) (Serum-binding protein)].

HC127_HUMAN
θ value	0.0431538 (rank : 1285)	NC score	0.048000 (rank : 1731)
Query Neighborhood Hits	2923	Target Neighborhood Hits	292	Shared Neighborhood Hits	159
SwissProt Accessions	Q9NQZ6, Q5JTF9, Q9H9C3, Q9H9H7, Q9ULQ4	Gene names	HCA127, KIAA1166
Domain Architecture	No domain graphic available
Description	Hepatocellular carcinoma-associated antigen 127.

HC127_MOUSE
θ value	0.0431538 (rank : 1286)	NC score	0.048000 (rank : 1732)
Query Neighborhood Hits	2923	Target Neighborhood Hits	292	Shared Neighborhood Hits	159
SwissProt Accessions	Q68FG0, Q6ZPW6	Gene names	Hca127, Kiaa1166
Domain Architecture	No domain graphic available
Description	Hepatocellular carcinoma-associated antigen 127 homolog.

I18RA_HUMAN
θ value	0.0431538 (rank : 1287)	NC score	0.087232 (rank : 1243)
Query Neighborhood Hits	2923	Target Neighborhood Hits	97	Shared Neighborhood Hits	72
SwissProt Accessions	O95256, Q53TT4, Q53TU5	Gene names	IL18RAP
Domain Architecture	No domain graphic available
Description	Interleukin-18 receptor accessory protein precursor (IL-18 receptor accessory protein) (IL-18RAcP) (Interleukin-18 receptor accessory protein-like) (IL-18Rbeta) (IL-1R accessory protein-like) (IL-1RAcPL) (Accessory protein-like) (AcPL) (IL-1R7) (CDw218b antigen).

INCE_MOUSE
θ value	0.0431538 (rank : 1288)	NC score	0.073916 (rank : 1287)
Query Neighborhood Hits	2923	Target Neighborhood Hits	903	Shared Neighborhood Hits	398
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

LEPR_HUMAN
θ value	0.0431538 (rank : 1289)	NC score	0.072913 (rank : 1292)
Query Neighborhood Hits	2923	Target Neighborhood Hits	112	Shared Neighborhood Hits	86
SwissProt Accessions	P48357, Q13592, Q13593, Q13594, Q92919, Q92920, Q92921	Gene names	LEPR, DB, OBR
Domain Architecture
Description	Leptin receptor precursor (LEP-R) (OB receptor) (OB-R) (HuB219) (CD295 antigen).

LRC45_HUMAN
θ value	0.0431538 (rank : 1290)	NC score	0.062518 (rank : 1386)
Query Neighborhood Hits	2923	Target Neighborhood Hits	933	Shared Neighborhood Hits	396
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

MYH2_HUMAN
θ value	0.0431538 (rank : 1291)	NC score	0.054333 (rank : 1597)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1491	Shared Neighborhood Hits	478
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

PAF49_HUMAN
θ value	0.0431538 (rank : 1292)	NC score	0.051240 (rank : 1678)
Query Neighborhood Hits	2923	Target Neighborhood Hits	169	Shared Neighborhood Hits	93
SwissProt Accessions	O15446, Q32N11, Q7Z5U2, Q9UPF6	Gene names	CD3EAP, ASE1, CAST, PAF49
Domain Architecture	No domain graphic available
Description	RNA polymerase I-associated factor PAF49 (Anti-sense to ERCC-1 protein) (ASE-1) (CD3-epsilon-associated protein) (CD3E-associated protein) (CAST).

PHF20_MOUSE
θ value	0.0431538 (rank : 1293)	NC score	0.041370 (rank : 1824)
Query Neighborhood Hits	2923	Target Neighborhood Hits	513	Shared Neighborhood Hits	219
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

RYK_MOUSE
θ value	0.0431538 (rank : 1294)	NC score	0.471303 (rank : 881)
Query Neighborhood Hits	2923	Target Neighborhood Hits	715	Shared Neighborhood Hits	663
SwissProt Accessions	Q01887, Q61890	Gene names	Ryk, Mrk
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1) (Kinase VIK) (NYK- R) (Met-related kinase).

SEM4C_HUMAN
θ value	0.0431538 (rank : 1295)	NC score	0.019423 (rank : 2216)
Query Neighborhood Hits	2923	Target Neighborhood Hits	84	Shared Neighborhood Hits	35
SwissProt Accessions	Q9C0C4, Q7Z5X0	Gene names	SEMA4C, KIAA1739
Domain Architecture
Description	Semaphorin-4C precursor.

TRI36_HUMAN
θ value	0.0431538 (rank : 1296)	NC score	0.026672 (rank : 2072)
Query Neighborhood Hits	2923	Target Neighborhood Hits	282	Shared Neighborhood Hits	93
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

TRI42_HUMAN
θ value	0.0431538 (rank : 1297)	NC score	0.045023 (rank : 1766)
Query Neighborhood Hits	2923	Target Neighborhood Hits	283	Shared Neighborhood Hits	74
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRIM1_HUMAN
θ value	0.0431538 (rank : 1298)	NC score	0.027245 (rank : 2060)
Query Neighborhood Hits	2923	Target Neighborhood Hits	345	Shared Neighborhood Hits	111
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

VRK1_MOUSE
θ value	0.0431538 (rank : 1299)	NC score	0.389227 (rank : 948)
Query Neighborhood Hits	2923	Target Neighborhood Hits	583	Shared Neighborhood Hits	566
SwissProt Accessions	Q80X41, O88635, O88636, Q8C2P7, Q91YH9	Gene names	Vrk1
Domain Architecture
Description	Serine/threonine-protein kinase VRK1 (EC 2.7.11.1) (Vaccinia-related kinase 1) (Serine/threonine-protein kinase 51PK).

ATS19_MOUSE
θ value	0.0563607 (rank : 1300)	NC score	0.011041 (rank : 2440)
Query Neighborhood Hits	2923	Target Neighborhood Hits	188	Shared Neighborhood Hits	36
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATS2_MOUSE
θ value	0.0563607 (rank : 1301)	NC score	0.010447 (rank : 2458)
Query Neighborhood Hits	2923	Target Neighborhood Hits	179	Shared Neighborhood Hits	27
SwissProt Accessions	Q8C9W3	Gene names	Adamts2
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

BAT2_HUMAN
θ value	0.0563607 (rank : 1302)	NC score	0.067249 (rank : 1327)
Query Neighborhood Hits	2923	Target Neighborhood Hits	931	Shared Neighborhood Hits	355
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BT2A1_HUMAN
θ value	0.0563607 (rank : 1303)	NC score	0.026355 (rank : 2079)
Query Neighborhood Hits	2923	Target Neighborhood Hits	185	Shared Neighborhood Hits	98
SwissProt Accessions	Q7KYR7, O00475, P78408, Q7KYQ7, Q7Z386, Q9NU62	Gene names	BTN2A1, BT2.1, BTF1
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A1 precursor.

CCD11_HUMAN
θ value	0.0563607 (rank : 1304)	NC score	0.077382 (rank : 1273)
Query Neighborhood Hits	2923	Target Neighborhood Hits	822	Shared Neighborhood Hits	382
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CCD12_MOUSE
θ value	0.0563607 (rank : 1305)	NC score	0.035421 (rank : 1923)
Query Neighborhood Hits	2923	Target Neighborhood Hits	50	Shared Neighborhood Hits	33
SwissProt Accessions	Q8R344, Q9CZH5	Gene names	Ccdc12
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 12.

CHD9_MOUSE
θ value	0.0563607 (rank : 1306)	NC score	0.014743 (rank : 2330)
Query Neighborhood Hits	2923	Target Neighborhood Hits	427	Shared Neighborhood Hits	165
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

CUTL2_HUMAN
θ value	0.0563607 (rank : 1307)	NC score	0.042501 (rank : 1804)
Query Neighborhood Hits	2923	Target Neighborhood Hits	906	Shared Neighborhood Hits	328
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

FXL19_MOUSE
θ value	0.0563607 (rank : 1308)	NC score	0.016660 (rank : 2272)
Query Neighborhood Hits	2923	Target Neighborhood Hits	217	Shared Neighborhood Hits	74
SwissProt Accessions	Q6PB97, Q7TSH0, Q8BIB4	Gene names	Fbxl19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

GOGA4_MOUSE
θ value	0.0563607 (rank : 1309)	NC score	0.064306 (rank : 1350)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1939	Shared Neighborhood Hits	607
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

GRAP1_HUMAN
θ value	0.0563607 (rank : 1310)	NC score	0.061367 (rank : 1407)
Query Neighborhood Hits	2923	Target Neighborhood Hits	944	Shared Neighborhood Hits	371
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

HPPD_MOUSE
θ value	0.0563607 (rank : 1311)	NC score	0.020130 (rank : 2202)
Query Neighborhood Hits	2923	Target Neighborhood Hits	6	Shared Neighborhood Hits	4
SwissProt Accessions	P49429, P97322, Q3UEQ0, Q91WV9	Gene names	Hpd
Domain Architecture
Description	4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) (4HPPD) (HPD) (4- hydroxyphenylpyruvic acid oxidase) (HPPDase) (F protein) (F Alloantigen).

HXB5_MOUSE
θ value	0.0563607 (rank : 1312)	NC score	-0.014263 (rank : 3073)
Query Neighborhood Hits	2923	Target Neighborhood Hits	337	Shared Neighborhood Hits	26
SwissProt Accessions	P09079, Q3ZAY8	Gene names	Hoxb5, Hox-2.1, Hoxb-5
Domain Architecture
Description	Homeobox protein Hox-B5 (Hox-2.1) (MU-1) (H24.1).

I12R1_MOUSE
θ value	0.0563607 (rank : 1313)	NC score	0.091146 (rank : 1230)
Query Neighborhood Hits	2923	Target Neighborhood Hits	70	Shared Neighborhood Hits	57
SwissProt Accessions	Q60837	Gene names	Il12rb1, Il12rb
Domain Architecture
Description	Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) (CD212 antigen).

IF4G1_MOUSE
θ value	0.0563607 (rank : 1314)	NC score	0.028541 (rank : 2032)
Query Neighborhood Hits	2923	Target Neighborhood Hits	534	Shared Neighborhood Hits	189
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

IL27B_MOUSE
θ value	0.0563607 (rank : 1315)	NC score	0.065926 (rank : 1335)
Query Neighborhood Hits	2923	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	O35228	Gene names	Ebi3, Il17b
Domain Architecture
Description	Interleukin-27 beta chain precursor (IL-27B) (Epstein-Barr virus- induced gene 3 protein homolog).

KC1G1_MOUSE
θ value	0.0563607 (rank : 1316)	NC score	0.541236 (rank : 772)
Query Neighborhood Hits	2923	Target Neighborhood Hits	713	Shared Neighborhood Hits	694
SwissProt Accessions	Q8BTH8	Gene names	Csnk1g1
Domain Architecture
Description	Casein kinase I isoform gamma-1 (EC 2.7.11.1) (CKI-gamma 1).

MACF4_HUMAN
θ value	0.0563607 (rank : 1317)	NC score	0.050024 (rank : 1706)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1321	Shared Neighborhood Hits	429
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

MAP2_MOUSE
θ value	0.0563607 (rank : 1318)	NC score	0.048501 (rank : 1728)
Query Neighborhood Hits	2923	Target Neighborhood Hits	342	Shared Neighborhood Hits	170
SwissProt Accessions	P20357	Gene names	Map2, Mtap2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2).

MERL_HUMAN
θ value	0.0563607 (rank : 1319)	NC score	0.038367 (rank : 1867)
Query Neighborhood Hits	2923	Target Neighborhood Hits	532	Shared Neighborhood Hits	254
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

MERL_MOUSE
θ value	0.0563607 (rank : 1320)	NC score	0.038585 (rank : 1863)
Query Neighborhood Hits	2923	Target Neighborhood Hits	524	Shared Neighborhood Hits	256
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

MUCB_HUMAN
θ value	0.0563607 (rank : 1321)	NC score	0.042051 (rank : 1813)
Query Neighborhood Hits	2923	Target Neighborhood Hits	233	Shared Neighborhood Hits	77
SwissProt Accessions	P04220	Gene names
Domain Architecture	No domain graphic available
Description	Ig mu heavy chain disease protein (BOT).

MYH9_HUMAN
θ value	0.0563607 (rank : 1322)	NC score	0.056697 (rank : 1541)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1762	Shared Neighborhood Hits	569
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

NOLC1_HUMAN
θ value	0.0563607 (rank : 1323)	NC score	0.088744 (rank : 1239)
Query Neighborhood Hits	2923	Target Neighborhood Hits	452	Shared Neighborhood Hits	218
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

AFF2_MOUSE
θ value	0.0736092 (rank : 1324)	NC score	0.034557 (rank : 1939)
Query Neighborhood Hits	2923	Target Neighborhood Hits	225	Shared Neighborhood Hits	107
SwissProt Accessions	O55112	Gene names	Aff2, Fmr2, Ox19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation protein 2 homolog) (Protein FMR-2) (FMR2P) (Protein Ox19).

APXL_HUMAN
θ value	0.0736092 (rank : 1325)	NC score	0.051500 (rank : 1672)
Query Neighborhood Hits	2923	Target Neighborhood Hits	553	Shared Neighborhood Hits	228
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

ASXL1_MOUSE
θ value	0.0736092 (rank : 1326)	NC score	0.022757 (rank : 2152)
Query Neighborhood Hits	2923	Target Neighborhood Hits	182	Shared Neighborhood Hits	78
SwissProt Accessions	P59598	Gene names	Asxl1, Kiaa0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

BAT2_MOUSE
θ value	0.0736092 (rank : 1327)	NC score	0.061468 (rank : 1402)
Query Neighborhood Hits	2923	Target Neighborhood Hits	947	Shared Neighborhood Hits	359
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CABIN_HUMAN
θ value	0.0736092 (rank : 1328)	NC score	0.044229 (rank : 1774)
Query Neighborhood Hits	2923	Target Neighborhood Hits	490	Shared Neighborhood Hits	172
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

CCD46_MOUSE
θ value	0.0736092 (rank : 1329)	NC score	0.068330 (rank : 1318)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1405	Shared Neighborhood Hits	490
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

CP250_MOUSE
θ value	0.0736092 (rank : 1330)	NC score	0.060504 (rank : 1427)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1583	Shared Neighborhood Hits	519
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

ERBB4_HUMAN
θ value	0.0736092 (rank : 1331)	NC score	0.557226 (rank : 728)
Query Neighborhood Hits	2923	Target Neighborhood Hits	910	Shared Neighborhood Hits	768
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

FBX41_HUMAN
θ value	0.0736092 (rank : 1332)	NC score	0.040737 (rank : 1834)
Query Neighborhood Hits	2923	Target Neighborhood Hits	475	Shared Neighborhood Hits	214
SwissProt Accessions	Q8TF61	Gene names	FBXO41, FBX41, KIAA1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

FBX41_MOUSE
θ value	0.0736092 (rank : 1333)	NC score	0.040949 (rank : 1829)
Query Neighborhood Hits	2923	Target Neighborhood Hits	430	Shared Neighborhood Hits	201
SwissProt Accessions	Q6NS60, Q6P7W4, Q6ZPG1	Gene names	Fbxo41, D6Ertd538e, Kiaa1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

FCRLA_MOUSE
θ value	0.0736092 (rank : 1334)	NC score	0.131117 (rank : 1157)
Query Neighborhood Hits	2923	Target Neighborhood Hits	110	Shared Neighborhood Hits	91
SwissProt Accessions	Q920A9, Q3T9Q2, Q8K3U9, Q8VHP5	Gene names	Fcrla, Fcrl, Fcrl1, Fcrlm1, Fcrx, Freb
Domain Architecture	No domain graphic available
Description	Fc receptor-like and mucin-like 1 precursor (Fc receptor-like A) (Fc receptor homolog expressed in B-cells) (Fc receptor-related protein X) (FcRX) (Fc receptor-like protein).

HXB5_HUMAN
θ value	0.0736092 (rank : 1335)	NC score	-0.014661 (rank : 3074)
Query Neighborhood Hits	2923	Target Neighborhood Hits	332	Shared Neighborhood Hits	22
SwissProt Accessions	P09067, P09069	Gene names	HOXB5, HOX2A
Domain Architecture
Description	Homeobox protein Hox-B5 (Hox-2A) (HHO.C10) (HU-1).

I11RA_HUMAN
θ value	0.0736092 (rank : 1336)	NC score	0.092828 (rank : 1227)
Query Neighborhood Hits	2923	Target Neighborhood Hits	138	Shared Neighborhood Hits	102
SwissProt Accessions	Q14626, Q16542, Q7KYJ7	Gene names	IL11RA
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha chain precursor (IL-11R-alpha) (IL- 11RA).

I13R2_HUMAN
θ value	0.0736092 (rank : 1337)	NC score	0.030465 (rank : 1999)
Query Neighborhood Hits	2923	Target Neighborhood Hits	41	Shared Neighborhood Hits	24
SwissProt Accessions	Q14627, O00667	Gene names	IL13RA2, IL13R
Domain Architecture	No domain graphic available
Description	Interleukin-13 receptor alpha-2 chain precursor (Interleukin-13- binding protein) (CD213a2 antigen).

I20RA_MOUSE
θ value	0.0736092 (rank : 1338)	NC score	0.026111 (rank : 2085)
Query Neighborhood Hits	2923	Target Neighborhood Hits	37	Shared Neighborhood Hits	19
SwissProt Accessions	Q6PHB0, Q8BW64	Gene names	Il20ra
Domain Architecture	No domain graphic available
Description	Interleukin-20 receptor alpha chain precursor (IL-20R-alpha) (IL- 20R1).

I27RA_MOUSE
θ value	0.0736092 (rank : 1339)	NC score	0.060355 (rank : 1430)
Query Neighborhood Hits	2923	Target Neighborhood Hits	55	Shared Neighborhood Hits	45
SwissProt Accessions	O70394	Gene names	Il27ra, Tccr, Wsx1
Domain Architecture	No domain graphic available
Description	Interleukin-27 receptor alpha chain precursor (IL-27R-alpha) (WSX-1) (Type I T-cell cytokine receptor) (TCCR).

IF4B_MOUSE
θ value	0.0736092 (rank : 1340)	NC score	0.022066 (rank : 2168)
Query Neighborhood Hits	2923	Target Neighborhood Hits	368	Shared Neighborhood Hits	118
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

ILRL1_MOUSE
θ value	0.0736092 (rank : 1341)	NC score	0.146257 (rank : 1141)
Query Neighborhood Hits	2923	Target Neighborhood Hits	172	Shared Neighborhood Hits	144
SwissProt Accessions	P14719, Q05208	Gene names	Il1rl1, Ly84, St2, Ste2
Domain Architecture
Description	Interleukin-1 receptor-like 1 precursor (ST2 protein) (T1 protein) (Lymphocyte antigen 84).

K0319_HUMAN
θ value	0.0736092 (rank : 1342)	NC score	0.042640 (rank : 1800)
Query Neighborhood Hits	2923	Target Neighborhood Hits	154	Shared Neighborhood Hits	64
SwissProt Accessions	Q5VV43, Q9UJC8, Q9Y4G7	Gene names	KIAA0319
Domain Architecture	No domain graphic available
Description	Protein KIAA0319 precursor.

KC1G1_HUMAN
θ value	0.0736092 (rank : 1343)	NC score	0.539244 (rank : 781)
Query Neighborhood Hits	2923	Target Neighborhood Hits	708	Shared Neighborhood Hits	692
SwissProt Accessions	Q9HCP0, Q96AE9, Q9HCP1	Gene names	CSNK1G1
Domain Architecture
Description	Casein kinase I isoform gamma-1 (EC 2.7.11.1) (CKI-gamma 1).

KV1C_HUMAN
θ value	0.0736092 (rank : 1344)	NC score	-0.000298 (rank : 2851)
Query Neighborhood Hits	2923	Target Neighborhood Hits	257	Shared Neighborhood Hits	80
SwissProt Accessions	P01595	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-I region Bi.

MA1B1_HUMAN
θ value	0.0736092 (rank : 1345)	NC score	0.009854 (rank : 2476)
Query Neighborhood Hits	2923	Target Neighborhood Hits	125	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UKM7, Q5VSG3, Q9BRS9, Q9Y5K7	Gene names	MAN1B1
Domain Architecture
Description	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (EC 3.2.1.113) (ER alpha-1,2-mannosidase) (Mannosidase alpha class 1B member 1) (Man9GlcNAc2-specific-processing alpha-mannosidase).

MFAP3_HUMAN
θ value	0.0736092 (rank : 1346)	NC score	0.110176 (rank : 1182)
Query Neighborhood Hits	2923	Target Neighborhood Hits	91	Shared Neighborhood Hits	89
SwissProt Accessions	P55082, Q9NXA7	Gene names	MFAP3
Domain Architecture
Description	Microfibril-associated glycoprotein 3 precursor.

MYH8_HUMAN
θ value	0.0736092 (rank : 1347)	NC score	0.054819 (rank : 1583)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1610	Shared Neighborhood Hits	524
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

PAPOG_HUMAN
θ value	0.0736092 (rank : 1348)	NC score	0.011211 (rank : 2434)
Query Neighborhood Hits	2923	Target Neighborhood Hits	44	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BWT3, Q969N1, Q9H8L2, Q9HAD0	Gene names	PAPOLG, PAP2, PAPG
Domain Architecture
Description	Poly(A) polymerase gamma (EC 2.7.7.19) (PAP gamma) (Polynucleotide adenylyltransferase gamma) (SRP RNA 3' adenylating enzyme) (Neo- poly(A) polymerase) (Neo-PAP).

RB6I2_HUMAN
θ value	0.0736092 (rank : 1349)	NC score	0.062674 (rank : 1382)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1584	Shared Neighborhood Hits	526
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

RIMB2_HUMAN
θ value	0.0736092 (rank : 1350)	NC score	0.098319 (rank : 1209)
Query Neighborhood Hits	2923	Target Neighborhood Hits	263	Shared Neighborhood Hits	120
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

RP1_MOUSE
θ value	0.0736092 (rank : 1351)	NC score	0.038212 (rank : 1872)
Query Neighborhood Hits	2923	Target Neighborhood Hits	104	Shared Neighborhood Hits	44
SwissProt Accessions	P56716	Gene names	Rp1, Orp1, Rp1h
Domain Architecture
Description	Oxygen-regulated protein 1 (Retinitis pigmentosa RP1 protein homolog).

SEM3C_HUMAN
θ value	0.0736092 (rank : 1352)	NC score	0.020677 (rank : 2188)
Query Neighborhood Hits	2923	Target Neighborhood Hits	106	Shared Neighborhood Hits	61
SwissProt Accessions	Q99985	Gene names	SEMA3C, SEMAE
Domain Architecture
Description	Semaphorin-3C precursor (Semaphorin E) (Sema E).

SEM4C_MOUSE
θ value	0.0736092 (rank : 1353)	NC score	0.013648 (rank : 2365)
Query Neighborhood Hits	2923	Target Neighborhood Hits	77	Shared Neighborhood Hits	34
SwissProt Accessions	Q64151	Gene names	Sema4c, Semacl1, Semai
Domain Architecture
Description	Semaphorin-4C precursor (Semaphorin I) (Sema I) (Semaphorin C-like 1) (M-Sema F).

TRAK1_HUMAN
θ value	0.0736092 (rank : 1354)	NC score	0.051288 (rank : 1677)
Query Neighborhood Hits	2923	Target Neighborhood Hits	660	Shared Neighborhood Hits	300
SwissProt Accessions	Q9UPV9, Q96B69	Gene names	TRAK1, KIAA1042, OIP106
Domain Architecture	No domain graphic available
Description	Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase- interacting protein).

TRI42_MOUSE
θ value	0.0736092 (rank : 1355)	NC score	0.035389 (rank : 1924)
Query Neighborhood Hits	2923	Target Neighborhood Hits	316	Shared Neighborhood Hits	69
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

ZN318_MOUSE
θ value	0.0736092 (rank : 1356)	NC score	0.048881 (rank : 1719)
Query Neighborhood Hits	2923	Target Neighborhood Hits	642	Shared Neighborhood Hits	301
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

AKAP2_MOUSE
θ value	0.0961366 (rank : 1357)	NC score	0.043643 (rank : 1784)
Query Neighborhood Hits	2923	Target Neighborhood Hits	385	Shared Neighborhood Hits	181
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

BRD4_MOUSE
θ value	0.0961366 (rank : 1358)	NC score	0.062036 (rank : 1392)
Query Neighborhood Hits	2923	Target Neighborhood Hits	845	Shared Neighborhood Hits	447
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

CD248_MOUSE
θ value	0.0961366 (rank : 1359)	NC score	0.021578 (rank : 2172)
Query Neighborhood Hits	2923	Target Neighborhood Hits	578	Shared Neighborhood Hits	165
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CKAP4_HUMAN
θ value	0.0961366 (rank : 1360)	NC score	0.052675 (rank : 1644)
Query Neighborhood Hits	2923	Target Neighborhood Hits	592	Shared Neighborhood Hits	262
SwissProt Accessions	Q07065, Q504S5, Q53ES6	Gene names	CKAP4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

ENAM_HUMAN
θ value	0.0961366 (rank : 1361)	NC score	0.028498 (rank : 2034)
Query Neighborhood Hits	2923	Target Neighborhood Hits	227	Shared Neighborhood Hits	93
SwissProt Accessions	Q9NRM1, Q9H3D1	Gene names	ENAM
Domain Architecture
Description	Enamelin precursor.

FPRP_HUMAN
θ value	0.0961366 (rank : 1362)	NC score	0.110919 (rank : 1180)
Query Neighborhood Hits	2923	Target Neighborhood Hits	130	Shared Neighborhood Hits	116
SwissProt Accessions	Q9P2B2, Q8N2K6	Gene names	PTGFRN, CD9P1, FPRP, KIAA1436
Domain Architecture
Description	Prostaglandin F2 receptor negative regulator precursor (Prostaglandin F2-alpha receptor regulatory protein) (Prostaglandin F2-alpha receptor-associated protein) (CD9 partner 1) (CD9P-1) (CD315 antigen).

HOOK3_HUMAN
θ value	0.0961366 (rank : 1363)	NC score	0.050993 (rank : 1682)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1070	Shared Neighborhood Hits	394
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

HPPD_HUMAN
θ value	0.0961366 (rank : 1364)	NC score	0.019335 (rank : 2217)
Query Neighborhood Hits	2923	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	P32754, Q13234	Gene names	HPD, PPD
Domain Architecture
Description	4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) (4HPPD) (HPD) (HPPDase) (4-hydroxyphenylpyruvic acid oxidase).

HS105_MOUSE
θ value	0.0961366 (rank : 1365)	NC score	0.014797 (rank : 2329)
Query Neighborhood Hits	2923	Target Neighborhood Hits	129	Shared Neighborhood Hits	71
SwissProt Accessions	Q61699, Q3TNS2, Q3UIY8, Q62578, Q62579, Q6A0A5, Q8C430, Q8VCW6	Gene names	Hsph1, Hsp105, Hsp110, Kiaa0201
Domain Architecture
Description	Heat-shock protein 105 kDa (Heat shock-related 100 kDa protein E7I) (HSP-E7I) (Heat shock 110 kDa protein) (42 degrees C-HSP).

IL12B_MOUSE
θ value	0.0961366 (rank : 1366)	NC score	0.048648 (rank : 1724)
Query Neighborhood Hits	2923	Target Neighborhood Hits	43	Shared Neighborhood Hits	41
SwissProt Accessions	P43432, Q9QUM1	Gene names	Il12b
Domain Architecture
Description	Interleukin-12 beta chain precursor (IL-12B) (IL-12 p40) (Cytotoxic lymphocyte maturation factor 40 kDa subunit) (CLMF p40).

IL2RG_HUMAN
θ value	0.0961366 (rank : 1367)	NC score	0.019850 (rank : 2206)
Query Neighborhood Hits	2923	Target Neighborhood Hits	34	Shared Neighborhood Hits	16
SwissProt Accessions	P31785	Gene names	IL2RG
Domain Architecture
Description	Cytokine receptor common gamma chain precursor (Gamma-C) (Interleukin- 2 receptor gamma chain) (IL-2R gamma chain) (p64) (CD132 antigen).

LIPA2_HUMAN
θ value	0.0961366 (rank : 1368)	NC score	0.054310 (rank : 1600)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1044	Shared Neighborhood Hits	403
SwissProt Accessions	O75334	Gene names	PPFIA2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

LIPA2_MOUSE
θ value	0.0961366 (rank : 1369)	NC score	0.055918 (rank : 1559)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1282	Shared Neighborhood Hits	480
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

LV5A_HUMAN
θ value	0.0961366 (rank : 1370)	NC score	0.006200 (rank : 2597)
Query Neighborhood Hits	2923	Target Neighborhood Hits	220	Shared Neighborhood Hits	80
SwissProt Accessions	P01719	Gene names
Domain Architecture	No domain graphic available
Description	Ig lambda chain V-V region DEL.

MYH1_HUMAN
θ value	0.0961366 (rank : 1371)	NC score	0.054686 (rank : 1586)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1478	Shared Neighborhood Hits	491
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

MYH1_MOUSE
θ value	0.0961366 (rank : 1372)	NC score	0.054632 (rank : 1588)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1461	Shared Neighborhood Hits	484
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

MYH8_MOUSE
θ value	0.0961366 (rank : 1373)	NC score	0.054040 (rank : 1613)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1600	Shared Neighborhood Hits	518
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MYH9_MOUSE
θ value	0.0961366 (rank : 1374)	NC score	0.056643 (rank : 1542)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1829	Shared Neighborhood Hits	589
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

NOP56_MOUSE
θ value	0.0961366 (rank : 1375)	NC score	0.028958 (rank : 2026)
Query Neighborhood Hits	2923	Target Neighborhood Hits	129	Shared Neighborhood Hits	75
SwissProt Accessions	Q9D6Z1, Q3UD45, Q8BVL1, Q8VDT2, Q99LT8, Q9CT15	Gene names	Nol5a, Nop56
Domain Architecture
Description	Nucleolar protein Nop56 (Nucleolar protein 5A).

OGFR_HUMAN
θ value	0.0961366 (rank : 1376)	NC score	0.063992 (rank : 1357)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1582	Shared Neighborhood Hits	441
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

PDL2_HUMAN
θ value	0.0961366 (rank : 1377)	NC score	0.140003 (rank : 1148)
Query Neighborhood Hits	2923	Target Neighborhood Hits	114	Shared Neighborhood Hits	107
SwissProt Accessions	Q9BQ51, Q5T7Z6, Q6JXL8, Q6JXL9	Gene names	PDCD1LG2, B7DC, CD273, PDCD1L2, PDL2
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 2 precursor (Programmed death ligand 2) (PD-L2) (PD-1-ligand 2) (PDCD1 ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD273 antigen).

RRBP1_MOUSE
θ value	0.0961366 (rank : 1378)	NC score	0.059278 (rank : 1463)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1650	Shared Neighborhood Hits	544
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

SLAF8_MOUSE
θ value	0.0961366 (rank : 1379)	NC score	0.064090 (rank : 1356)
Query Neighborhood Hits	2923	Target Neighborhood Hits	52	Shared Neighborhood Hits	48
SwissProt Accessions	Q9D3G2, Q8R3T7	Gene names	Slamf8, Blame
Domain Architecture	No domain graphic available
Description	SLAM family member 8 precursor (B-lymphocyte activator macrophage expressed).

TIMD4_HUMAN
θ value	0.0961366 (rank : 1380)	NC score	0.026619 (rank : 2074)
Query Neighborhood Hits	2923	Target Neighborhood Hits	55	Shared Neighborhood Hits	35
SwissProt Accessions	Q96H15	Gene names	TIMD4, TIM4
Domain Architecture	No domain graphic available
Description	T-cell immunoglobulin and mucin domain-containing protein 4 precursor (TIMD-4) (T-cell membrane protein 4) (TIM-4).

TOP2A_HUMAN
θ value	0.0961366 (rank : 1381)	NC score	0.014963 (rank : 2322)
Query Neighborhood Hits	2923	Target Neighborhood Hits	135	Shared Neighborhood Hits	64
SwissProt Accessions	P11388, Q71UN1, Q9HB24, Q9HB25, Q9HB26, Q9UP44, Q9UQP9	Gene names	TOP2A, TOP2
Domain Architecture
Description	DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme).

2B1A_HUMAN
θ value	0.125558 (rank : 1382)	NC score	0.004411 (rank : 2664)
Query Neighborhood Hits	2923	Target Neighborhood Hits	211	Shared Neighborhood Hits	60
SwissProt Accessions	Q30167, Q9MYF5	Gene names	HLA-DRB1
Domain Architecture
Description	HLA class II histocompatibility antigen, DRB1-10 beta chain precursor (MHC class I antigen DRB1*10) (DRw10).

AKAP5_HUMAN
θ value	0.125558 (rank : 1383)	NC score	0.024994 (rank : 2107)
Query Neighborhood Hits	2923	Target Neighborhood Hits	41	Shared Neighborhood Hits	19
SwissProt Accessions	P24588	Gene names	AKAP5, AKAP79
Domain Architecture
Description	A-kinase anchor protein 5 (A-kinase anchor protein 79 kDa) (AKAP 79) (cAMP-dependent protein kinase regulatory subunit II high affinity- binding protein) (H21).

ATX2L_MOUSE
θ value	0.125558 (rank : 1384)	NC score	0.032981 (rank : 1969)
Query Neighborhood Hits	2923	Target Neighborhood Hits	401	Shared Neighborhood Hits	158
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

BTNL1_MOUSE
θ value	0.125558 (rank : 1385)	NC score	0.086299 (rank : 1246)
Query Neighborhood Hits	2923	Target Neighborhood Hits	151	Shared Neighborhood Hits	124
SwissProt Accessions	Q7TST0, O70356	Gene names	Btnl1, Btnl3, Gm316, Ng10
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 1 precursor.

CENPE_HUMAN
θ value	0.125558 (rank : 1386)	NC score	0.055703 (rank : 1562)
Query Neighborhood Hits	2923	Target Neighborhood Hits	2060	Shared Neighborhood Hits	631
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

FOXM1_HUMAN
θ value	0.125558 (rank : 1387)	NC score	0.001980 (rank : 2764)
Query Neighborhood Hits	2923	Target Neighborhood Hits	167	Shared Neighborhood Hits	57
SwissProt Accessions	Q08050, O43258, O43259, O43260, Q4ZGG7, Q9BRL2	Gene names	FOXM1, FKHL16, HFH11, MPP2, WIN
Domain Architecture
Description	Forkhead box protein M1 (Forkhead-related protein FKHL16) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/fork-head homolog 11) (HFH-11) (Winged helix factor from INS-1 cells) (M-phase phosphoprotein 2) (MPM-2 reactive phosphoprotein 2) (Transcription factor Trident).

GCC2_HUMAN
θ value	0.125558 (rank : 1388)	NC score	0.060115 (rank : 1437)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1558	Shared Neighborhood Hits	500
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

GP73_MOUSE
θ value	0.125558 (rank : 1389)	NC score	0.057463 (rank : 1507)
Query Neighborhood Hits	2923	Target Neighborhood Hits	506	Shared Neighborhood Hits	271
SwissProt Accessions	Q91XA2	Gene names	Golph2
Domain Architecture	No domain graphic available
Description	Golgi phosphoprotein 2 (Golgi membrane protein GP73).

HCLS1_HUMAN
θ value	0.125558 (rank : 1390)	NC score	0.024607 (rank : 2117)
Query Neighborhood Hits	2923	Target Neighborhood Hits	358	Shared Neighborhood Hits	140
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

IRAK3_HUMAN
θ value	0.125558 (rank : 1391)	NC score	0.492142 (rank : 853)
Query Neighborhood Hits	2923	Target Neighborhood Hits	644	Shared Neighborhood Hits	586
SwissProt Accessions	Q9Y616	Gene names	IRAK3
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1) (IRAK-3) (IL- 1 receptor-associated kinase M) (IRAK-M).

LIRB5_HUMAN
θ value	0.125558 (rank : 1392)	NC score	0.032000 (rank : 1982)
Query Neighborhood Hits	2923	Target Neighborhood Hits	100	Shared Neighborhood Hits	62
SwissProt Accessions	O75023, Q8N760	Gene names	LILRB5, LIR8
Domain Architecture
Description	Leukocyte immunoglobulin-like receptor subfamily B member 5 precursor (Leukocyte immunoglobulin-like receptor 8) (LIR-8) (CD85c antigen).

MOR2A_MOUSE
θ value	0.125558 (rank : 1393)	NC score	0.020239 (rank : 2198)
Query Neighborhood Hits	2923	Target Neighborhood Hits	220	Shared Neighborhood Hits	117
SwissProt Accessions	Q69ZX6, Q5QNQ7, Q6P547	Gene names	Morc2a, Kiaa0852, Zcwcc1
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 2A (Zinc finger CW-type coiled-coil domain protein 1).

MYH4_HUMAN
θ value	0.125558 (rank : 1394)	NC score	0.052454 (rank : 1651)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1377	Shared Neighborhood Hits	457
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

MYH4_MOUSE
θ value	0.125558 (rank : 1395)	NC score	0.052547 (rank : 1648)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1476	Shared Neighborhood Hits	479
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

OX2G_MOUSE
θ value	0.125558 (rank : 1396)	NC score	0.140144 (rank : 1147)
Query Neighborhood Hits	2923	Target Neighborhood Hits	105	Shared Neighborhood Hits	101
SwissProt Accessions	O54901, O54816, Q9JHD5	Gene names	Cd200, Mox2
Domain Architecture
Description	OX-2 membrane glycoprotein precursor (MRC OX-2 antigen) (CD200 antigen).

RBP24_HUMAN
θ value	0.125558 (rank : 1397)	NC score	0.060049 (rank : 1438)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1559	Shared Neighborhood Hits	499
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

SETBP_HUMAN
θ value	0.125558 (rank : 1398)	NC score	0.036795 (rank : 1893)
Query Neighborhood Hits	2923	Target Neighborhood Hits	305	Shared Neighborhood Hits	145
SwissProt Accessions	Q9Y6X0, Q9UEF3	Gene names	SETBP1, KIAA0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

SETD8_MOUSE
θ value	0.125558 (rank : 1399)	NC score	0.022610 (rank : 2156)
Query Neighborhood Hits	2923	Target Neighborhood Hits	131	Shared Neighborhood Hits	68
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).

SIGIR_MOUSE
θ value	0.125558 (rank : 1400)	NC score	0.088768 (rank : 1238)
Query Neighborhood Hits	2923	Target Neighborhood Hits	95	Shared Neighborhood Hits	71
SwissProt Accessions	Q9JLZ8, Q52L48	Gene names	Sigirr, Tir8
Domain Architecture	No domain graphic available
Description	Single Ig IL-1-related receptor (Single Ig IL-1R-related molecule) (Single immunoglobulin domain-containing IL1R-related protein) (Toll/interleukin-1 receptor 8) (TIR8).

SLAF1_MOUSE
θ value	0.125558 (rank : 1401)	NC score	0.049782 (rank : 1710)
Query Neighborhood Hits	2923	Target Neighborhood Hits	60	Shared Neighborhood Hits	49
SwissProt Accessions	Q9QUM4, Q9QXZ3	Gene names	Slamf1, Slam
Domain Architecture
Description	Signaling lymphocytic activation molecule precursor (CD150 antigen).

SRPK1_MOUSE
θ value	0.125558 (rank : 1402)	NC score	0.460376 (rank : 893)
Query Neighborhood Hits	2923	Target Neighborhood Hits	639	Shared Neighborhood Hits	579
SwissProt Accessions	O70551, O70193, Q99JT3	Gene names	Srpk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SRPK1 (EC 2.7.11.1) (Serine/arginine- rich protein-specific kinase 1) (SR-protein-specific kinase 1) (SFRS protein kinase 1).

TCAL5_HUMAN
θ value	0.125558 (rank : 1403)	NC score	0.024834 (rank : 2111)
Query Neighborhood Hits	2923	Target Neighborhood Hits	806	Shared Neighborhood Hits	249
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

TTF2_MOUSE
θ value	0.125558 (rank : 1404)	NC score	0.020629 (rank : 2189)
Query Neighborhood Hits	2923	Target Neighborhood Hits	364	Shared Neighborhood Hits	161
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

ZN291_HUMAN
θ value	0.125558 (rank : 1405)	NC score	0.063507 (rank : 1365)
Query Neighborhood Hits	2923	Target Neighborhood Hits	647	Shared Neighborhood Hits	317
SwissProt Accessions	Q9BY12	Gene names	ZNF291
Domain Architecture
Description	Zinc finger protein 291.

ANGL3_MOUSE
θ value	0.163984 (rank : 1406)	NC score	0.043229 (rank : 1792)
Query Neighborhood Hits	2923	Target Neighborhood Hits	306	Shared Neighborhood Hits	157
SwissProt Accessions	Q9R182	Gene names	Angptl3
Domain Architecture
Description	Angiopoietin-related protein 3 precursor (Angiopoietin-like 3).

BLNK_MOUSE
θ value	0.163984 (rank : 1407)	NC score	0.053985 (rank : 1615)
Query Neighborhood Hits	2923	Target Neighborhood Hits	296	Shared Neighborhood Hits	141
SwissProt Accessions	Q9QUN3, O88504	Gene names	Blnk, Bash, Ly57, Slp65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65) (Lymphocyte antigen 57).

CCD91_HUMAN
θ value	0.163984 (rank : 1408)	NC score	0.068750 (rank : 1316)
Query Neighborhood Hits	2923	Target Neighborhood Hits	868	Shared Neighborhood Hits	389
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

CD226_MOUSE
θ value	0.163984 (rank : 1409)	NC score	0.063984 (rank : 1358)
Query Neighborhood Hits	2923	Target Neighborhood Hits	64	Shared Neighborhood Hits	58
SwissProt Accessions	Q8K4F0	Gene names	Cd226, Pta1
Domain Architecture
Description	CD226 antigen precursor (Platelet and T-cell activation antigen 1).

CD45_HUMAN
θ value	0.163984 (rank : 1410)	NC score	0.068040 (rank : 1323)
Query Neighborhood Hits	2923	Target Neighborhood Hits	243	Shared Neighborhood Hits	104
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

CD4_HUMAN
θ value	0.163984 (rank : 1411)	NC score	0.105446 (rank : 1195)
Query Neighborhood Hits	2923	Target Neighborhood Hits	122	Shared Neighborhood Hits	97
SwissProt Accessions	P01730, Q4ZGK2, Q5U066	Gene names	CD4
Domain Architecture
Description	T-cell surface glycoprotein CD4 precursor (T-cell surface antigen T4/Leu-3).

CENPF_HUMAN
θ value	0.163984 (rank : 1412)	NC score	0.058266 (rank : 1487)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1932	Shared Neighborhood Hits	569
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CS016_HUMAN
θ value	0.163984 (rank : 1413)	NC score	0.062975 (rank : 1375)
Query Neighborhood Hits	2923	Target Neighborhood Hits	310	Shared Neighborhood Hits	168
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

E41L3_MOUSE
θ value	0.163984 (rank : 1414)	NC score	0.013533 (rank : 2368)
Query Neighborhood Hits	2923	Target Neighborhood Hits	250	Shared Neighborhood Hits	118
SwissProt Accessions	Q9WV92, Q9R102	Gene names	Epb41l3, Dal1, Epb4.1l3
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1).

EGFR_HUMAN
θ value	0.163984 (rank : 1415)	NC score	0.555458 (rank : 739)
Query Neighborhood Hits	2923	Target Neighborhood Hits	939	Shared Neighborhood Hits	770
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

EGFR_MOUSE
θ value	0.163984 (rank : 1416)	NC score	0.556075 (rank : 736)
Query Neighborhood Hits	2923	Target Neighborhood Hits	927	Shared Neighborhood Hits	776
SwissProt Accessions	Q01279	Gene names	Egfr
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1).

ENL_HUMAN
θ value	0.163984 (rank : 1417)	NC score	0.061406 (rank : 1404)
Query Neighborhood Hits	2923	Target Neighborhood Hits	305	Shared Neighborhood Hits	156
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

FLIP1_HUMAN
θ value	0.163984 (rank : 1418)	NC score	0.059867 (rank : 1446)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1405	Shared Neighborhood Hits	490
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

GOGA4_HUMAN
θ value	0.163984 (rank : 1419)	NC score	0.065476 (rank : 1342)
Query Neighborhood Hits	2923	Target Neighborhood Hits	2034	Shared Neighborhood Hits	620
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

HPLN3_MOUSE
θ value	0.163984 (rank : 1420)	NC score	0.025795 (rank : 2092)
Query Neighborhood Hits	2923	Target Neighborhood Hits	95	Shared Neighborhood Hits	75
SwissProt Accessions	Q80WM5, Q80XX3	Gene names	Hapln3, Lpr3
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 3 precursor (Link protein 3).

ICB1_MOUSE
θ value	0.163984 (rank : 1421)	NC score	0.013453 (rank : 2370)
Query Neighborhood Hits	2923	Target Neighborhood Hits	69	Shared Neighborhood Hits	37
SwissProt Accessions	Q91YX0	Gene names	Icb1
Domain Architecture	No domain graphic available
Description	Induced by contact to basement membrane 1 protein homolog (ICB-1 protein).

INAR1_MOUSE
θ value	0.163984 (rank : 1422)	NC score	0.028222 (rank : 2045)
Query Neighborhood Hits	2923	Target Neighborhood Hits	36	Shared Neighborhood Hits	21
SwissProt Accessions	P33896	Gene names	Ifnar1, Ifar, Ifnar
Domain Architecture	No domain graphic available
Description	Interferon-alpha/beta receptor alpha chain precursor (IFN-alpha-REC).

K1219_HUMAN
θ value	0.163984 (rank : 1423)	NC score	0.012590 (rank : 2394)
Query Neighborhood Hits	2923	Target Neighborhood Hits	85	Shared Neighborhood Hits	35
SwissProt Accessions	Q86X10, Q5TG31, Q8N3D1, Q8WWC0, Q9H3X8, Q9UJR1, Q9ULK1, Q9Y3G9	Gene names	KIAA1219
Domain Architecture	No domain graphic available
Description	Protein KIAA1219.

K1914_MOUSE
θ value	0.163984 (rank : 1424)	NC score	0.030781 (rank : 1996)
Query Neighborhood Hits	2923	Target Neighborhood Hits	216	Shared Neighborhood Hits	116
SwissProt Accessions	Q5DTU0, Q8BID1, Q8K2G0	Gene names	Kiaa1914
Domain Architecture	No domain graphic available
Description	Protein KIAA1914.

LIRA3_HUMAN
θ value	0.163984 (rank : 1425)	NC score	0.043400 (rank : 1786)
Query Neighborhood Hits	2923	Target Neighborhood Hits	92	Shared Neighborhood Hits	63
SwissProt Accessions	Q8N6C8, O15469, O15470, O75016, Q8N151, Q8N154, Q8NHJ1, Q8NHJ2, Q8NHJ3, Q8NHJ4	Gene names	LILRA3, ILT6, LIR4
Domain Architecture	No domain graphic available
Description	Leukocyte immunoglobulin-like receptor subfamily A member 3 precursor (Leukocyte immunoglobulin-like receptor 4) (LIR-4) (Immunoglobulin- like transcript 6) (ILT-6) (Monocyte inhibitory receptor HM43/HM31) (CD85e antigen).

MOG_HUMAN
θ value	0.163984 (rank : 1426)	NC score	0.044531 (rank : 1769)
Query Neighborhood Hits	2923	Target Neighborhood Hits	73	Shared Neighborhood Hits	63
SwissProt Accessions	Q16653, O00713, O00714, O00715, Q13054, Q13055, Q14855, Q92891, Q92892, Q92893, Q92894, Q92895, Q93053, Q96KU9, Q96KV0, Q96KV1, Q99605	Gene names	MOG
Domain Architecture
Description	Myelin-oligodendrocyte glycoprotein precursor.

MRE11_HUMAN
θ value	0.163984 (rank : 1427)	NC score	0.016316 (rank : 2284)
Query Neighborhood Hits	2923	Target Neighborhood Hits	95	Shared Neighborhood Hits	47
SwissProt Accessions	P49959, O43475	Gene names	MRE11A, HNGS1, MRE11
Domain Architecture
Description	Double-strand break repair protein MRE11A (MRE11 homolog 1) (MRE11 meiotic recombination 11 homolog A).

PKHA6_MOUSE
θ value	0.163984 (rank : 1428)	NC score	0.034666 (rank : 1936)
Query Neighborhood Hits	2923	Target Neighborhood Hits	591	Shared Neighborhood Hits	250
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PORIM_MOUSE
θ value	0.163984 (rank : 1429)	NC score	0.024723 (rank : 2113)
Query Neighborhood Hits	2923	Target Neighborhood Hits	43	Shared Neighborhood Hits	22
SwissProt Accessions	Q91Z22, Q3T9F6, Q3TLL2, Q3U1R6, Q8CEX4	Gene names	Tmem123
Domain Architecture	No domain graphic available
Description	Porimin precursor (Transmembrane protein 123).

POT15_HUMAN
θ value	0.163984 (rank : 1430)	NC score	0.025666 (rank : 2095)
Query Neighborhood Hits	2923	Target Neighborhood Hits	893	Shared Neighborhood Hits	334
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

RBBP6_MOUSE
θ value	0.163984 (rank : 1431)	NC score	0.065906 (rank : 1337)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1014	Shared Neighborhood Hits	405
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

SAS6_MOUSE
θ value	0.163984 (rank : 1432)	NC score	0.057703 (rank : 1501)
Query Neighborhood Hits	2923	Target Neighborhood Hits	931	Shared Neighborhood Hits	371
SwissProt Accessions	Q80UK7, Q9CYT4	Gene names	Sass6, Sas6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog.

SIGL9_HUMAN
θ value	0.163984 (rank : 1433)	NC score	0.105035 (rank : 1197)
Query Neighborhood Hits	2923	Target Neighborhood Hits	76	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Y336, Q9BYI9	Gene names	SIGLEC9
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 9 precursor (Siglec-9) (Protein FOAP-9).

SMC2_MOUSE
θ value	0.163984 (rank : 1434)	NC score	0.052456 (rank : 1650)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1131	Shared Neighborhood Hits	436
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

SRPK1_HUMAN
θ value	0.163984 (rank : 1435)	NC score	0.460586 (rank : 891)
Query Neighborhood Hits	2923	Target Neighborhood Hits	706	Shared Neighborhood Hits	616
SwissProt Accessions	Q96SB4, Q12890, Q5R364, Q5R365, Q8IY12	Gene names	SRPK1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SRPK1 (EC 2.7.11.1) (Serine/arginine- rich protein-specific kinase 1) (SR-protein-specific kinase 1) (SFRS protein kinase 1).

SYYC_MOUSE
θ value	0.163984 (rank : 1436)	NC score	0.013326 (rank : 2374)
Query Neighborhood Hits	2923	Target Neighborhood Hits	27	Shared Neighborhood Hits	8
SwissProt Accessions	Q91WQ3, Q3TEC8, Q3U9A1, Q3UTA7, Q8BVT2, Q8C183	Gene names	Yars
Domain Architecture	No domain graphic available
Description	Tyrosyl-tRNA synthetase, cytoplasmic (EC 6.1.1.1) (Tyrosyl--tRNA ligase) (TyrRS).

TUFT1_MOUSE
θ value	0.163984 (rank : 1437)	NC score	0.050750 (rank : 1685)
Query Neighborhood Hits	2923	Target Neighborhood Hits	732	Shared Neighborhood Hits	305
SwissProt Accessions	O08970	Gene names	Tuft1
Domain Architecture
Description	Tuftelin.

ZAN_MOUSE
θ value	0.163984 (rank : 1438)	NC score	0.043050 (rank : 1795)
Query Neighborhood Hits	2923	Target Neighborhood Hits	808	Shared Neighborhood Hits	198
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

ZO2_MOUSE
θ value	0.163984 (rank : 1439)	NC score	0.011696 (rank : 2420)
Query Neighborhood Hits	2923	Target Neighborhood Hits	296	Shared Neighborhood Hits	83
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

ANR11_HUMAN
θ value	0.21417 (rank : 1440)	NC score	0.036090 (rank : 1903)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1289	Shared Neighborhood Hits	451
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

ANR21_HUMAN
θ value	0.21417 (rank : 1441)	NC score	0.023934 (rank : 2129)
Query Neighborhood Hits	2923	Target Neighborhood Hits	864	Shared Neighborhood Hits	320
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

CAF1A_MOUSE
θ value	0.21417 (rank : 1442)	NC score	0.061360 (rank : 1408)
Query Neighborhood Hits	2923	Target Neighborhood Hits	736	Shared Neighborhood Hits	346
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CASP_MOUSE
θ value	0.21417 (rank : 1443)	NC score	0.058457 (rank : 1480)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1152	Shared Neighborhood Hits	432
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CC47_MOUSE
θ value	0.21417 (rank : 1444)	NC score	0.017683 (rank : 2245)
Query Neighborhood Hits	2923	Target Neighborhood Hits	245	Shared Neighborhood Hits	81
SwissProt Accessions	Q9D024, Q3TSB5, Q3V1S7, Q8C5D9, Q920S6	Gene names	Ccdc47, Asp4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor (Adipocyte-specific protein 4).

CCD46_HUMAN
θ value	0.21417 (rank : 1445)	NC score	0.068539 (rank : 1317)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1430	Shared Neighborhood Hits	490
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

CCD93_HUMAN
θ value	0.21417 (rank : 1446)	NC score	0.058338 (rank : 1483)
Query Neighborhood Hits	2923	Target Neighborhood Hits	600	Shared Neighborhood Hits	290
SwissProt Accessions	Q567U6, Q4LE78, Q53TJ2, Q8TBX5, Q9H6R5, Q9NV15	Gene names	CCDC93
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 93.

CJ012_HUMAN
θ value	0.21417 (rank : 1447)	NC score	0.060646 (rank : 1423)
Query Neighborhood Hits	2923	Target Neighborhood Hits	467	Shared Neighborhood Hits	204
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

CJ118_HUMAN
θ value	0.21417 (rank : 1448)	NC score	0.053357 (rank : 1630)
Query Neighborhood Hits	2923	Target Neighborhood Hits	937	Shared Neighborhood Hits	352
SwissProt Accessions	Q7Z3E2, Q2M2V6, Q6NS91, Q7RTP1, Q8N117, Q8N3G3, Q8N6C2, Q9NWA3	Gene names	C10orf118
Domain Architecture	No domain graphic available
Description	Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2).

CNTFR_HUMAN
θ value	0.21417 (rank : 1449)	NC score	0.056223 (rank : 1549)
Query Neighborhood Hits	2923	Target Neighborhood Hits	66	Shared Neighborhood Hits	53
SwissProt Accessions	P26992	Gene names	CNTFR
Domain Architecture
Description	Ciliary neurotrophic factor receptor alpha precursor (CNTFR alpha).

CO8A2_HUMAN
θ value	0.21417 (rank : 1450)	NC score	0.013586 (rank : 2367)
Query Neighborhood Hits	2923	Target Neighborhood Hits	299	Shared Neighborhood Hits	92
SwissProt Accessions	P25067, Q8TEJ5	Gene names	COL8A2
Domain Architecture
Description	Collagen alpha-2(VIII) chain precursor (Endothelial collagen).

CP250_HUMAN
θ value	0.21417 (rank : 1451)	NC score	0.062673 (rank : 1383)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1805	Shared Neighborhood Hits	556
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

CSKI1_MOUSE
θ value	0.21417 (rank : 1452)	NC score	0.043274 (rank : 1791)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1031	Shared Neighborhood Hits	364
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CUTL1_MOUSE
θ value	0.21417 (rank : 1453)	NC score	0.055425 (rank : 1567)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1620	Shared Neighborhood Hits	538
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

DESP_HUMAN
θ value	0.21417 (rank : 1454)	NC score	0.059695 (rank : 1453)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1470	Shared Neighborhood Hits	498
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

E41L3_HUMAN
θ value	0.21417 (rank : 1455)	NC score	0.009855 (rank : 2475)
Query Neighborhood Hits	2923	Target Neighborhood Hits	113	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y2J2, O95713, Q9BRP5	Gene names	EPB41L3, DAL1, KIAA0987
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1).

ECM1_HUMAN
θ value	0.21417 (rank : 1456)	NC score	0.030730 (rank : 1997)
Query Neighborhood Hits	2923	Target Neighborhood Hits	182	Shared Neighborhood Hits	84
SwissProt Accessions	Q16610	Gene names	ECM1
Domain Architecture
Description	Extracellular matrix protein 1 precursor (Secretory component p85).

EMSY_MOUSE
θ value	0.21417 (rank : 1457)	NC score	0.036240 (rank : 1902)
Query Neighborhood Hits	2923	Target Neighborhood Hits	294	Shared Neighborhood Hits	132
SwissProt Accessions	Q8BMB0, Q5FWK5, Q80XU1, Q8VDW9	Gene names	Emsy
Domain Architecture
Description	Protein EMSY.

ESCO2_HUMAN
θ value	0.21417 (rank : 1458)	NC score	0.019595 (rank : 2213)
Query Neighborhood Hits	2923	Target Neighborhood Hits	45	Shared Neighborhood Hits	25
SwissProt Accessions	Q56NI9	Gene names	ESCO2
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO2 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 2) (ECO1 homolog 2).

FCGR3_MOUSE
θ value	0.21417 (rank : 1459)	NC score	0.093186 (rank : 1225)
Query Neighborhood Hits	2923	Target Neighborhood Hits	98	Shared Neighborhood Hits	75
SwissProt Accessions	P08508	Gene names	Fcgr3
Domain Architecture
Description	Low affinity immunoglobulin gamma Fc region receptor III precursor (IgG Fc receptor III) (Fc-gamma RIII) (FcRIII).

GAK10_HUMAN
θ value	0.21417 (rank : 1460)	NC score	0.013318 (rank : 2375)
Query Neighborhood Hits	2923	Target Neighborhood Hits	289	Shared Neighborhood Hits	109
SwissProt Accessions	P87889, P10263, P10264, Q69385, Q9UKH6	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q33.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K10 Gag protein) (HERV-K107 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK11_HUMAN
θ value	0.21417 (rank : 1461)	NC score	0.014620 (rank : 2337)
Query Neighborhood Hits	2923	Target Neighborhood Hits	409	Shared Neighborhood Hits	144
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK2_HUMAN
θ value	0.21417 (rank : 1462)	NC score	0.014244 (rank : 2347)
Query Neighborhood Hits	2923	Target Neighborhood Hits	406	Shared Neighborhood Hits	137
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK4_HUMAN
θ value	0.21417 (rank : 1463)	NC score	0.014703 (rank : 2333)
Query Neighborhood Hits	2923	Target Neighborhood Hits	415	Shared Neighborhood Hits	147
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK5_HUMAN
θ value	0.21417 (rank : 1464)	NC score	0.014584 (rank : 2339)
Query Neighborhood Hits	2923	Target Neighborhood Hits	429	Shared Neighborhood Hits	145
SwissProt Accessions	P62684	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K113 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GP125_HUMAN
θ value	0.21417 (rank : 1465)	NC score	0.050062 (rank : 1703)
Query Neighborhood Hits	2923	Target Neighborhood Hits	327	Shared Neighborhood Hits	93
SwissProt Accessions	Q8IWK6, Q6UXK9, Q86SQ5, Q8TC55	Gene names	GPR125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

GP125_MOUSE
θ value	0.21417 (rank : 1466)	NC score	0.051751 (rank : 1666)
Query Neighborhood Hits	2923	Target Neighborhood Hits	329	Shared Neighborhood Hits	98
SwissProt Accessions	Q7TT36, Q6PE67, Q8VE71	Gene names	Gpr125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

HUWE1_MOUSE
θ value	0.21417 (rank : 1467)	NC score	0.013992 (rank : 2361)
Query Neighborhood Hits	2923	Target Neighborhood Hits	406	Shared Neighborhood Hits	150
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

ICOSL_MOUSE
θ value	0.21417 (rank : 1468)	NC score	0.091514 (rank : 1229)
Query Neighborhood Hits	2923	Target Neighborhood Hits	93	Shared Neighborhood Hits	82
SwissProt Accessions	Q9JHJ8	Gene names	Icoslg, B7h2, B7rp1, Icosl
Domain Architecture
Description	ICOS ligand precursor (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (LICOS) (CD275 antigen).

KC1G2_HUMAN
θ value	0.21417 (rank : 1469)	NC score	0.513629 (rank : 826)
Query Neighborhood Hits	2923	Target Neighborhood Hits	693	Shared Neighborhood Hits	680
SwissProt Accessions	P78368, O00704, Q8WUB1	Gene names	CSNK1G2
Domain Architecture
Description	Casein kinase I isoform gamma-2 (EC 2.7.11.1) (CKI-gamma 2).

LIRB1_HUMAN
θ value	0.21417 (rank : 1470)	NC score	0.028330 (rank : 2043)
Query Neighborhood Hits	2923	Target Neighborhood Hits	116	Shared Neighborhood Hits	65
SwissProt Accessions	Q8NHL6, O75024, O75025, Q8NHJ9, Q8NHK0	Gene names	LILRB1, ILT2, LIR1, MIR7
Domain Architecture	No domain graphic available
Description	Leukocyte immunoglobulin-like receptor subfamily B member 1 precursor (Leukocyte immunoglobulin-like receptor 1) (LIR-1) (Immunoglobulin- like transcript 2) (ILT-2) (Monocyte/macrophage immunoglobulin-like receptor 7) (MIR-7) (CD85j antigen).

LIRB4_MOUSE
θ value	0.21417 (rank : 1471)	NC score	0.015455 (rank : 2304)
Query Neighborhood Hits	2923	Target Neighborhood Hits	56	Shared Neighborhood Hits	32
SwissProt Accessions	Q64281, Q64312	Gene names	Lilrb4, Gp49b
Domain Architecture	No domain graphic available
Description	Leukocyte immunoglobulin-like receptor subfamily B member 4 precursor (Mast cell surface glycoprotein Gp49B).

NP1L3_HUMAN
θ value	0.21417 (rank : 1472)	NC score	0.024225 (rank : 2126)
Query Neighborhood Hits	2923	Target Neighborhood Hits	172	Shared Neighborhood Hits	101
SwissProt Accessions	Q99457, O60788	Gene names	NAP1L3, BNAP
Domain Architecture
Description	Nucleosome assembly protein 1-like 3.

PHC2_HUMAN
θ value	0.21417 (rank : 1473)	NC score	0.020323 (rank : 2197)
Query Neighborhood Hits	2923	Target Neighborhood Hits	388	Shared Neighborhood Hits	166
SwissProt Accessions	Q8IXK0, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7	Gene names	PHC2, EDR2, PH2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2).

PI3R4_MOUSE
θ value	0.21417 (rank : 1474)	NC score	0.311154 (rank : 998)
Query Neighborhood Hits	2923	Target Neighborhood Hits	535	Shared Neighborhood Hits	364
SwissProt Accessions	Q8VD65, Q56A65, Q8C948, Q8C9D7, Q9CVC5	Gene names	Pik3r4
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 4 (EC 2.7.11.1) (PI3- kinase regulatory subunit 4).

RBM34_HUMAN
θ value	0.21417 (rank : 1475)	NC score	-0.002555 (rank : 2921)
Query Neighborhood Hits	2923	Target Neighborhood Hits	208	Shared Neighborhood Hits	36
SwissProt Accessions	P42696, Q8N2Z8, Q9H5A1	Gene names	RBM34, KIAA0117
Domain Architecture
Description	RNA-binding protein 34 (RNA-binding motif protein 34).

SNPC4_MOUSE
θ value	0.21417 (rank : 1476)	NC score	0.024286 (rank : 2124)
Query Neighborhood Hits	2923	Target Neighborhood Hits	237	Shared Neighborhood Hits	111
SwissProt Accessions	Q8BP86, Q6PGG7, Q80UG9, Q810L1	Gene names	Snapc4
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit).

STXB4_MOUSE
θ value	0.21417 (rank : 1477)	NC score	0.036630 (rank : 1898)
Query Neighborhood Hits	2923	Target Neighborhood Hits	629	Shared Neighborhood Hits	275
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

SYNE1_HUMAN
θ value	0.21417 (rank : 1478)	NC score	0.046034 (rank : 1751)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1484	Shared Neighborhood Hits	466
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

SYYC_HUMAN
θ value	0.21417 (rank : 1479)	NC score	0.012622 (rank : 2392)
Query Neighborhood Hits	2923	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	P54577, O43276, Q53EN1	Gene names	YARS
Domain Architecture
Description	Tyrosyl-tRNA synthetase, cytoplasmic (EC 6.1.1.1) (Tyrosyl--tRNA ligase) (TyrRS).

TRI66_MOUSE
θ value	0.21417 (rank : 1480)	NC score	0.022748 (rank : 2153)
Query Neighborhood Hits	2923	Target Neighborhood Hits	491	Shared Neighborhood Hits	210
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

UBP8_HUMAN
θ value	0.21417 (rank : 1481)	NC score	0.022218 (rank : 2166)
Query Neighborhood Hits	2923	Target Neighborhood Hits	751	Shared Neighborhood Hits	345
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

VRK1_HUMAN
θ value	0.21417 (rank : 1482)	NC score	0.383370 (rank : 955)
Query Neighborhood Hits	2923	Target Neighborhood Hits	584	Shared Neighborhood Hits	566
SwissProt Accessions	Q99986	Gene names	VRK1
Domain Architecture
Description	Serine/threonine-protein kinase VRK1 (EC 2.7.11.1) (Vaccinia-related kinase 1).

BTLA_HUMAN
θ value	0.279714 (rank : 1483)	NC score	0.036315 (rank : 1901)
Query Neighborhood Hits	2923	Target Neighborhood Hits	21	Shared Neighborhood Hits	15
SwissProt Accessions	Q7Z6A9, Q6ZNH9	Gene names	BTLA
Domain Architecture	No domain graphic available
Description	B- and T-lymphocyte attenuator precursor (B- and T-lymphocyte- associated protein) (CD272 antigen).

CAC1H_HUMAN
θ value	0.279714 (rank : 1484)	NC score	0.003804 (rank : 2689)
Query Neighborhood Hits	2923	Target Neighborhood Hits	307	Shared Neighborhood Hits	87
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

CCD39_MOUSE
θ value	0.279714 (rank : 1485)	NC score	0.061852 (rank : 1398)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1026	Shared Neighborhood Hits	407
SwissProt Accessions	Q9D5Y1, Q8CDG6	Gene names	Ccdc39, D3Ertd789e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

CD80_MOUSE
θ value	0.279714 (rank : 1486)	NC score	0.151763 (rank : 1135)
Query Neighborhood Hits	2923	Target Neighborhood Hits	136	Shared Neighborhood Hits	126
SwissProt Accessions	Q00609, Q61332	Gene names	Cd80, B7
Domain Architecture
Description	T-lymphocyte activation antigen CD80 precursor (Activation B7-1 antigen) (B7).

CDT1_MOUSE
θ value	0.279714 (rank : 1487)	NC score	0.024253 (rank : 2125)
Query Neighborhood Hits	2923	Target Neighborhood Hits	72	Shared Neighborhood Hits	39
SwissProt Accessions	Q8R4E9, Q8BUQ1, Q8BX29, Q8R3V0, Q8R4E8	Gene names	Cdt1, Ris2
Domain Architecture	No domain graphic available
Description	DNA replication factor Cdt1 (Double parked homolog) (DUP) (Retroviral insertion site 2 protein).

CHCH3_MOUSE
θ value	0.279714 (rank : 1488)	NC score	0.045719 (rank : 1754)
Query Neighborhood Hits	2923	Target Neighborhood Hits	249	Shared Neighborhood Hits	153
SwissProt Accessions	Q9CRB9	Gene names	Chchd3
Domain Architecture	No domain graphic available
Description	Coiled-coil-helix-coiled-coil-helix domain-containing protein 3.

CIR_MOUSE
θ value	0.279714 (rank : 1489)	NC score	0.029874 (rank : 2006)
Query Neighborhood Hits	2923	Target Neighborhood Hits	255	Shared Neighborhood Hits	112
SwissProt Accessions	Q9DA19, Q3V2N9, Q4KL44, Q52KL9, Q5FW66	Gene names	Cir
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor.

CN092_MOUSE
θ value	0.279714 (rank : 1490)	NC score	0.017869 (rank : 2240)
Query Neighborhood Hits	2923	Target Neighborhood Hits	206	Shared Neighborhood Hits	88
SwissProt Accessions	Q8BU11, Q80UI2, Q99PN9, Q9CS16	Gene names
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

CS007_MOUSE
θ value	0.279714 (rank : 1491)	NC score	0.031797 (rank : 1986)
Query Neighborhood Hits	2923	Target Neighborhood Hits	464	Shared Neighborhood Hits	185
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

DIDO1_HUMAN
θ value	0.279714 (rank : 1492)	NC score	0.035924 (rank : 1905)
Query Neighborhood Hits	2923	Target Neighborhood Hits	960	Shared Neighborhood Hits	328
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

E2AK4_HUMAN
θ value	0.279714 (rank : 1493)	NC score	0.652742 (rank : 544)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1012	Shared Neighborhood Hits	866
SwissProt Accessions	Q9P2K8, Q69YL7, Q6DC97, Q96GN6, Q9H5K1, Q9NSQ3, Q9NSZ5, Q9UJ56	Gene names	EIF2AK4, GCN2, KIAA1338
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 2-alpha kinase 4 (EC 2.7.11.1) (GCN2-like protein).

ERBB2_HUMAN
θ value	0.279714 (rank : 1494)	NC score	0.546457 (rank : 766)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1073	Shared Neighborhood Hits	820
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

ERMAP_HUMAN
θ value	0.279714 (rank : 1495)	NC score	0.014186 (rank : 2350)
Query Neighborhood Hits	2923	Target Neighborhood Hits	155	Shared Neighborhood Hits	69
SwissProt Accessions	Q96PL5, Q5VV53, Q6DUE0, Q7Z3X0, Q8NCV8, Q8NCW2, Q8NCW3, Q96PL6	Gene names	ERMAP, RD, SC
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor (hERMAP) (Scianna blood group antigen) (Radin blood group antigen).

FA50A_HUMAN
θ value	0.279714 (rank : 1496)	NC score	0.037018 (rank : 1889)
Query Neighborhood Hits	2923	Target Neighborhood Hits	264	Shared Neighborhood Hits	160
SwissProt Accessions	Q14320, Q5HY37	Gene names	FAM50A, DXS9928E, HXC26, XAP5
Domain Architecture
Description	Protein FAM50A (Protein XAP-5) (Protein HXC-26).

FA50A_MOUSE
θ value	0.279714 (rank : 1497)	NC score	0.040418 (rank : 1839)
Query Neighborhood Hits	2923	Target Neighborhood Hits	293	Shared Neighborhood Hits	169
SwissProt Accessions	Q9WV03, Q9D866	Gene names	Fam50a, D0HXS9928E, Xap5
Domain Architecture
Description	Protein FAM50A (XAP-5 protein).

GC3M_MOUSE
θ value	0.279714 (rank : 1498)	NC score	0.034259 (rank : 1945)
Query Neighborhood Hits	2923	Target Neighborhood Hits	215	Shared Neighborhood Hits	60
SwissProt Accessions	P03987	Gene names
Domain Architecture
Description	Ig gamma-3 chain C region, membrane-bound form.

GC3_MOUSE
θ value	0.279714 (rank : 1499)	NC score	0.033875 (rank : 1951)
Query Neighborhood Hits	2923	Target Neighborhood Hits	212	Shared Neighborhood Hits	58
SwissProt Accessions	P22436	Gene names
Domain Architecture	No domain graphic available
Description	Ig gamma-3 chain C region, secreted form.

GCAA_MOUSE
θ value	0.279714 (rank : 1500)	NC score	0.033785 (rank : 1953)
Query Neighborhood Hits	2923	Target Neighborhood Hits	210	Shared Neighborhood Hits	57
SwissProt Accessions	P01863	Gene names
Domain Architecture
Description	Ig gamma-2A chain C region, A allele.

GCAM_MOUSE
θ value	0.279714 (rank : 1501)	NC score	0.033946 (rank : 1949)
Query Neighborhood Hits	2923	Target Neighborhood Hits	214	Shared Neighborhood Hits	59
SwissProt Accessions	P01865	Gene names	Igh-1a
Domain Architecture
Description	Ig gamma-2A chain C region, membrane-bound form.

HB21_MOUSE
θ value	0.279714 (rank : 1502)	NC score	0.004543 (rank : 2660)
Query Neighborhood Hits	2923	Target Neighborhood Hits	213	Shared Neighborhood Hits	60
SwissProt Accessions	P04230, O78226	Gene names	H2-Eb1
Domain Architecture
Description	H-2 class II histocompatibility antigen, E-B beta chain precursor.

HB24_MOUSE
θ value	0.279714 (rank : 1503)	NC score	0.004136 (rank : 2672)
Query Neighborhood Hits	2923	Target Neighborhood Hits	213	Shared Neighborhood Hits	59
SwissProt Accessions	P20040	Gene names
Domain Architecture
Description	H-2 class II histocompatibility antigen, E-Q beta chain precursor (E- W17).

HB2I_MOUSE
θ value	0.279714 (rank : 1504)	NC score	0.004414 (rank : 2663)
Query Neighborhood Hits	2923	Target Neighborhood Hits	211	Shared Neighborhood Hits	59
SwissProt Accessions	P18468	Gene names	H2-Eb1
Domain Architecture
Description	H-2 class II histocompatibility antigen, I-A beta chain precursor.

HB2J_MOUSE
θ value	0.279714 (rank : 1505)	NC score	0.003781 (rank : 2690)
Query Neighborhood Hits	2923	Target Neighborhood Hits	214	Shared Neighborhood Hits	59
SwissProt Accessions	P18469	Gene names	H2-Eb1
Domain Architecture
Description	H-2 class II histocompatibility antigen, I-E beta chain precursor.

I11RB_MOUSE
θ value	0.279714 (rank : 1506)	NC score	0.098396 (rank : 1208)
Query Neighborhood Hits	2923	Target Neighborhood Hits	101	Shared Neighborhood Hits	85
SwissProt Accessions	P70225, O09074, Q78DW8	Gene names	Il11ra2
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha-2 chain precursor (IL-11R-alpha-2) (Interleukin-11 receptor beta chain) (IL-11R-beta).

IF3A_MOUSE
θ value	0.279714 (rank : 1507)	NC score	0.065294 (rank : 1344)
Query Neighborhood Hits	2923	Target Neighborhood Hits	871	Shared Neighborhood Hits	391
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

INAR1_HUMAN
θ value	0.279714 (rank : 1508)	NC score	0.029468 (rank : 2013)
Query Neighborhood Hits	2923	Target Neighborhood Hits	49	Shared Neighborhood Hits	29
SwissProt Accessions	P17181, Q53GW9, Q53H11, Q8WTZ2	Gene names	IFNAR1, IFNAR
Domain Architecture	No domain graphic available
Description	Interferon-alpha/beta receptor alpha chain precursor (IFN-alpha-REC).

IZUM1_HUMAN
θ value	0.279714 (rank : 1509)	NC score	0.034521 (rank : 1940)
Query Neighborhood Hits	2923	Target Neighborhood Hits	21	Shared Neighborhood Hits	17
SwissProt Accessions	Q8IYV9, Q6Q8P6, Q6Q8P7	Gene names	IZUMO1
Domain Architecture	No domain graphic available
Description	Izumo sperm-egg fusion protein 1 precursor (Sperm-specific protein izumo).

KC1G3_HUMAN
θ value	0.279714 (rank : 1510)	NC score	0.536310 (rank : 790)
Query Neighborhood Hits	2923	Target Neighborhood Hits	711	Shared Neighborhood Hits	697
SwissProt Accessions	Q9Y6M4, Q86WZ7, Q9Y6M3	Gene names	CSNK1G3
Domain Architecture
Description	Casein kinase I isoform gamma-3 (EC 2.7.11.1) (CKI-gamma 3).

LIPS_HUMAN
θ value	0.279714 (rank : 1511)	NC score	0.035382 (rank : 1925)
Query Neighborhood Hits	2923	Target Neighborhood Hits	314	Shared Neighborhood Hits	145
SwissProt Accessions	Q05469, Q3LRT2, Q6NSL7	Gene names	LIPE
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

LRC27_HUMAN
θ value	0.279714 (rank : 1512)	NC score	0.049088 (rank : 1716)
Query Neighborhood Hits	2923	Target Neighborhood Hits	710	Shared Neighborhood Hits	295
SwissProt Accessions	Q9C0I9, Q5SZH6, Q5SZH8, Q5SZH9, Q86XT5, Q8N7C8, Q8NA21	Gene names	LRRC27, KIAA1674
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 27.

MFAP3_MOUSE
θ value	0.279714 (rank : 1513)	NC score	0.105920 (rank : 1193)
Query Neighborhood Hits	2923	Target Neighborhood Hits	97	Shared Neighborhood Hits	91
SwissProt Accessions	Q922T2, Q8BHK5	Gene names	Mfap3
Domain Architecture	No domain graphic available
Description	Microfibril-associated glycoprotein 3 precursor.

PAR14_MOUSE
θ value	0.279714 (rank : 1514)	NC score	0.004888 (rank : 2643)
Query Neighborhood Hits	2923	Target Neighborhood Hits	113	Shared Neighborhood Hits	36
SwissProt Accessions	Q2EMV9, Q571C6, Q8BN35, Q8VDT6	Gene names	Parp14, Kiaa1268
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 14 (EC 2.4.2.30) (PARP-14) (Collaborator of STAT6) (CoaSt6).

PDE1C_HUMAN
θ value	0.279714 (rank : 1515)	NC score	-0.001984 (rank : 2908)
Query Neighborhood Hits	2923	Target Neighborhood Hits	134	Shared Neighborhood Hits	44
SwissProt Accessions	Q14123, Q14124	Gene names	PDE1C
Domain Architecture
Description	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (EC 3.1.4.17) (Cam-PDE 1C) (hCam-3).

PHLB1_HUMAN
θ value	0.279714 (rank : 1516)	NC score	0.058106 (rank : 1490)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1038	Shared Neighborhood Hits	434
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PIBF1_HUMAN
θ value	0.279714 (rank : 1517)	NC score	0.067138 (rank : 1329)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1041	Shared Neighborhood Hits	409
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

PLCB1_HUMAN
θ value	0.279714 (rank : 1518)	NC score	0.037263 (rank : 1885)
Query Neighborhood Hits	2923	Target Neighborhood Hits	614	Shared Neighborhood Hits	287
SwissProt Accessions	Q9NQ66, O60325, Q5TFF7, Q5TGC9, Q8IV93, Q9BQW2, Q9H4H2, Q9H8H5, Q9NQ65, Q9NQH9, Q9NTH4, Q9UJP6, Q9UM26	Gene names	PLCB1, KIAA0581
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

RAD50_MOUSE
θ value	0.279714 (rank : 1519)	NC score	0.059865 (rank : 1447)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1366	Shared Neighborhood Hits	460
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

RTP3_MOUSE
θ value	0.279714 (rank : 1520)	NC score	0.044176 (rank : 1776)
Query Neighborhood Hits	2923	Target Neighborhood Hits	374	Shared Neighborhood Hits	174
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

SLIT2_HUMAN
θ value	0.279714 (rank : 1521)	NC score	0.043785 (rank : 1781)
Query Neighborhood Hits	2923	Target Neighborhood Hits	708	Shared Neighborhood Hits	125
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SMCA1_MOUSE
θ value	0.279714 (rank : 1522)	NC score	0.003693 (rank : 2696)
Query Neighborhood Hits	2923	Target Neighborhood Hits	117	Shared Neighborhood Hits	46
SwissProt Accessions	Q6PGB8, Q8BSS1, Q91Y58	Gene names	Smarca1, Snf2l
Domain Architecture	No domain graphic available
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1) (DNA-dependent ATPase SNF2L).

SOX13_HUMAN
θ value	0.279714 (rank : 1523)	NC score	0.009384 (rank : 2496)
Query Neighborhood Hits	2923	Target Neighborhood Hits	464	Shared Neighborhood Hits	163
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

TCPE_HUMAN
θ value	0.279714 (rank : 1524)	NC score	0.000941 (rank : 2805)
Query Neighborhood Hits	2923	Target Neighborhood Hits	39	Shared Neighborhood Hits	7
SwissProt Accessions	P48643	Gene names	CCT5, CCTE, KIAA0098
Domain Architecture
Description	T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon).

TTC12_MOUSE
θ value	0.279714 (rank : 1525)	NC score	0.001688 (rank : 2772)
Query Neighborhood Hits	2923	Target Neighborhood Hits	98	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BW49	Gene names	Ttc12
Domain Architecture
Description	Tetratricopeptide repeat protein 12 (TPR repeat protein 12).

UN84B_HUMAN
θ value	0.279714 (rank : 1526)	NC score	0.015512 (rank : 2303)
Query Neighborhood Hits	2923	Target Neighborhood Hits	172	Shared Neighborhood Hits	96
SwissProt Accessions	Q9UH99, O75156, Q6B4H1, Q7Z3E3	Gene names	UNC84B, FRIGG, KIAA0668, RAB5IP, SUN2
Domain Architecture	No domain graphic available
Description	Sad1/unc-84-like protein 2 (Rab5-interacting protein) (Rab5IP).

VRK2_HUMAN
θ value	0.279714 (rank : 1527)	NC score	0.383526 (rank : 954)
Query Neighborhood Hits	2923	Target Neighborhood Hits	582	Shared Neighborhood Hits	555
SwissProt Accessions	Q86Y07, Q49AK9, Q53EU9, Q86Y08, Q86Y09, Q86Y10, Q86Y11, Q86Y12, Q8IXI5, Q99987	Gene names	VRK2
Domain Architecture
Description	Serine/threonine-protein kinase VRK2 (EC 2.7.11.1) (Vaccinia-related kinase 2).

WBP4_MOUSE
θ value	0.279714 (rank : 1528)	NC score	0.016824 (rank : 2267)
Query Neighborhood Hits	2923	Target Neighborhood Hits	100	Shared Neighborhood Hits	36
SwissProt Accessions	Q61048, Q8K1Z9, Q9CS45	Gene names	Wbp4, Fbp21, Fnbp21
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 4 (WBP-4) (Formin-binding protein 21).

ZC313_HUMAN
θ value	0.279714 (rank : 1529)	NC score	0.070759 (rank : 1304)
Query Neighborhood Hits	2923	Target Neighborhood Hits	772	Shared Neighborhood Hits	338
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

ZN688_HUMAN
θ value	0.279714 (rank : 1530)	NC score	-0.027727 (rank : 3097)
Query Neighborhood Hits	2923	Target Neighborhood Hits	873	Shared Neighborhood Hits	134
SwissProt Accessions	Q8WV14, O75701, Q8IW91, Q96MN0	Gene names	ZNF688
Domain Architecture	No domain graphic available
Description	Zinc finger protein 688.

ZN710_HUMAN
θ value	0.279714 (rank : 1531)	NC score	-0.028172 (rank : 3099)
Query Neighborhood Hits	2923	Target Neighborhood Hits	796	Shared Neighborhood Hits	84
SwissProt Accessions	Q8N1W2, Q6ZMK9, Q8NDU0	Gene names	ZNF710
Domain Architecture	No domain graphic available
Description	Zinc finger protein 710.

ADDA_MOUSE
θ value	0.365318 (rank : 1532)	NC score	0.029526 (rank : 2011)
Query Neighborhood Hits	2923	Target Neighborhood Hits	198	Shared Neighborhood Hits	112
SwissProt Accessions	Q9QYC0, Q9JLE3	Gene names	Add1
Domain Architecture
Description	Alpha-adducin (Erythrocyte adducin subunit alpha).

AIM1_HUMAN
θ value	0.365318 (rank : 1533)	NC score	0.021393 (rank : 2174)
Query Neighborhood Hits	2923	Target Neighborhood Hits	247	Shared Neighborhood Hits	107
SwissProt Accessions	Q9Y4K1, O00296, Q5VWJ2	Gene names	AIM1
Domain Architecture
Description	Absent in melanoma 1 protein.

ARI5B_HUMAN
θ value	0.365318 (rank : 1534)	NC score	0.028425 (rank : 2036)
Query Neighborhood Hits	2923	Target Neighborhood Hits	328	Shared Neighborhood Hits	167
SwissProt Accessions	Q14865, Q7Z3M4, Q8N421, Q9H786	Gene names	ARID5B, DESRT, MRF2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (Mrf1-like) (Modulator recognition factor 2) (MRF-2).

ASTN_MOUSE
θ value	0.365318 (rank : 1535)	NC score	0.014042 (rank : 2358)
Query Neighborhood Hits	2923	Target Neighborhood Hits	98	Shared Neighborhood Hits	23
SwissProt Accessions	Q61137, Q505A0, Q7TQG3, Q8CHH2	Gene names	Astn, Astn1, Kiaa0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor (Neuronal migration protein GC14).

CASC3_MOUSE
θ value	0.365318 (rank : 1536)	NC score	0.034406 (rank : 1943)
Query Neighborhood Hits	2923	Target Neighborhood Hits	333	Shared Neighborhood Hits	143
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

CASL_MOUSE
θ value	0.365318 (rank : 1537)	NC score	0.019006 (rank : 2221)
Query Neighborhood Hits	2923	Target Neighborhood Hits	225	Shared Neighborhood Hits	70
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

CCD11_MOUSE
θ value	0.365318 (rank : 1538)	NC score	0.065406 (rank : 1343)
Query Neighborhood Hits	2923	Target Neighborhood Hits	498	Shared Neighborhood Hits	246
SwissProt Accessions	Q9D439	Gene names	Ccdc11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CD79B_MOUSE
θ value	0.365318 (rank : 1539)	NC score	0.044819 (rank : 1768)
Query Neighborhood Hits	2923	Target Neighborhood Hits	150	Shared Neighborhood Hits	78
SwissProt Accessions	P15530	Gene names	Cd79b, Igb
Domain Architecture
Description	B-cell antigen receptor complex-associated protein beta-chain precursor (B-cell-specific glycoprotein B29) (Immunoglobulin- associated B29 protein) (IG-beta) (CD79b antigen).

CING_MOUSE
θ value	0.365318 (rank : 1540)	NC score	0.062935 (rank : 1377)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1432	Shared Neighborhood Hits	493
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

CN155_HUMAN
θ value	0.365318 (rank : 1541)	NC score	0.099475 (rank : 1205)
Query Neighborhood Hits	2923	Target Neighborhood Hits	385	Shared Neighborhood Hits	229
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

CNTFR_MOUSE
θ value	0.365318 (rank : 1542)	NC score	0.056316 (rank : 1546)
Query Neighborhood Hits	2923	Target Neighborhood Hits	74	Shared Neighborhood Hits	62
SwissProt Accessions	O88507, Q80T01	Gene names	Cntfr
Domain Architecture	No domain graphic available
Description	Ciliary neurotrophic factor receptor alpha precursor (CNTFR alpha).

CO4A3_HUMAN
θ value	0.365318 (rank : 1543)	NC score	0.014979 (rank : 2320)
Query Neighborhood Hits	2923	Target Neighborhood Hits	421	Shared Neighborhood Hits	113
SwissProt Accessions	Q01955, Q9BQT2	Gene names	COL4A3
Domain Architecture
Description	Collagen alpha-3(IV) chain precursor (Goodpasture antigen).

CRLF2_MOUSE
θ value	0.365318 (rank : 1544)	NC score	0.043205 (rank : 1794)
Query Neighborhood Hits	2923	Target Neighborhood Hits	39	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CII9, Q9CRJ6, Q9JIE7, Q9JIQ7, Q9JJH8, Q9JMD5	Gene names	Crlf2, Crlm2, Tpte2, Tslpr
Domain Architecture
Description	Cytokine receptor-like factor 2 precursor (Type I cytokine receptor delta 1) (Cytokine receptor-like molecule 2) (CRLM-2) (Thymic stromal lymphopoietin protein receptor) (TSLPR).

CSF3R_HUMAN
θ value	0.365318 (rank : 1545)	NC score	0.167531 (rank : 1114)
Query Neighborhood Hits	2923	Target Neighborhood Hits	140	Shared Neighborhood Hits	120
SwissProt Accessions	Q99062	Gene names	CSF3R, GCSFR
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

CTGE5_MOUSE
θ value	0.365318 (rank : 1546)	NC score	0.047197 (rank : 1738)
Query Neighborhood Hits	2923	Target Neighborhood Hits	928	Shared Neighborhood Hits	381
SwissProt Accessions	Q8R311, Q8CIE3	Gene names	Ctage5, Mea6, Mgea6
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 5 homolog (cTAGE-5 protein) (Meningioma-expressed antigen 6).

EFHB_MOUSE
θ value	0.365318 (rank : 1547)	NC score	0.009835 (rank : 2478)
Query Neighborhood Hits	2923	Target Neighborhood Hits	120	Shared Neighborhood Hits	32
SwissProt Accessions	Q8CDU5	Gene names	Efhb
Domain Architecture	No domain graphic available
Description	EF-hand domain-containing family member B.

FA13C_MOUSE
θ value	0.365318 (rank : 1548)	NC score	0.011574 (rank : 2423)
Query Neighborhood Hits	2923	Target Neighborhood Hits	79	Shared Neighborhood Hits	34
SwissProt Accessions	Q9DBR2	Gene names	Fam13c1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

FYB_HUMAN
θ value	0.365318 (rank : 1549)	NC score	0.042060 (rank : 1812)
Query Neighborhood Hits	2923	Target Neighborhood Hits	379	Shared Neighborhood Hits	170
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

GBP1_MOUSE
θ value	0.365318 (rank : 1550)	NC score	0.028052 (rank : 2048)
Query Neighborhood Hits	2923	Target Neighborhood Hits	302	Shared Neighborhood Hits	167
SwissProt Accessions	Q01514	Gene names	Gbp1, Gbp-1, Mag-1, Mpa1
Domain Architecture
Description	Interferon-induced guanylate-binding protein 1 (GTP-binding protein 1) (Guanine nucleotide-binding protein 1) (GBP-1) (mGBP1) (mGBP-1) (Interferon-gamma-inducible protein MAG-1).

HB2C_HUMAN
θ value	0.365318 (rank : 1551)	NC score	0.003341 (rank : 2713)
Query Neighborhood Hits	2923	Target Neighborhood Hits	211	Shared Neighborhood Hits	59
SwissProt Accessions	P01914	Gene names
Domain Architecture
Description	HLA class II histocompatibility antigen, DR-1 beta chain precursor (Clone P2-beta-4).

I11RA_MOUSE
θ value	0.365318 (rank : 1552)	NC score	0.094102 (rank : 1223)
Query Neighborhood Hits	2923	Target Neighborhood Hits	95	Shared Neighborhood Hits	81
SwissProt Accessions	Q64385, Q6NSQ0	Gene names	Il11ra1, Etl2, Il11ra
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha-1 chain precursor (IL-11R-alpha-1) (IL- 11RA1) (IL-11R-alpha) (IL-11RA) (Enhancer trap locus homolog 2) (Etl- 2) (NR-1).

I27RA_HUMAN
θ value	0.365318 (rank : 1553)	NC score	0.081024 (rank : 1258)
Query Neighborhood Hits	2923	Target Neighborhood Hits	60	Shared Neighborhood Hits	50
SwissProt Accessions	Q6UWB1, O60624	Gene names	IL27RA, CRL1, TCCR, WSX1
Domain Architecture	No domain graphic available
Description	Interleukin-27 receptor alpha chain precursor (IL-27R-alpha) (WSX-1) (Type I T-cell cytokine receptor) (TCCR) (Protein CRL1).

JHD3C_MOUSE
θ value	0.365318 (rank : 1554)	NC score	0.005269 (rank : 2619)
Query Neighborhood Hits	2923	Target Neighborhood Hits	84	Shared Neighborhood Hits	28
SwissProt Accessions	Q8VCD7, Q3UNP7, Q69ZZ5, Q8BUY6, Q8BWA1	Gene names	Jmjd2c, Jhdm3c, Kiaa0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C).

KTNA1_MOUSE
θ value	0.365318 (rank : 1555)	NC score	-0.004121 (rank : 2958)
Query Neighborhood Hits	2923	Target Neighborhood Hits	123	Shared Neighborhood Hits	25
SwissProt Accessions	Q9WV86	Gene names	Katna1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A1 (EC 3.6.4.3) (Katanin p60 subunit A1) (p60 katanin) (Lipotransin).

LEPR_MOUSE
θ value	0.365318 (rank : 1556)	NC score	0.066742 (rank : 1331)
Query Neighborhood Hits	2923	Target Neighborhood Hits	109	Shared Neighborhood Hits	82
SwissProt Accessions	P48356, O35686, O54986, Q61215, Q64309, Q9QWG3, Q9QWV5	Gene names	Lepr, db, Obr
Domain Architecture
Description	Leptin receptor precursor (LEP-R) (OB receptor) (OB-R) (B219) (CD295 antigen).

LMO7_HUMAN
θ value	0.365318 (rank : 1557)	NC score	0.025645 (rank : 2096)
Query Neighborhood Hits	2923	Target Neighborhood Hits	507	Shared Neighborhood Hits	195
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

LV7A_HUMAN
θ value	0.365318 (rank : 1558)	NC score	-0.000981 (rank : 2878)
Query Neighborhood Hits	2923	Target Neighborhood Hits	193	Shared Neighborhood Hits	61
SwissProt Accessions	P01720	Gene names
Domain Architecture	No domain graphic available
Description	Ig lambda chain V-VII region MOT.

M6PBP_MOUSE
θ value	0.365318 (rank : 1559)	NC score	0.014967 (rank : 2321)
Query Neighborhood Hits	2923	Target Neighborhood Hits	91	Shared Neighborhood Hits	56
SwissProt Accessions	Q9DBG5, Q3TK05, Q8BKV9, Q9CZK1	Gene names	M6prbp1, Tip47
Domain Architecture	No domain graphic available
Description	Mannose-6-phosphate receptor-binding protein 1 (Cargo selection protein TIP47).

MTSS1_HUMAN
θ value	0.365318 (rank : 1560)	NC score	0.036865 (rank : 1892)
Query Neighborhood Hits	2923	Target Neighborhood Hits	504	Shared Neighborhood Hits	196
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

NRBF2_MOUSE
θ value	0.365318 (rank : 1561)	NC score	0.019771 (rank : 2207)
Query Neighborhood Hits	2923	Target Neighborhood Hits	113	Shared Neighborhood Hits	66
SwissProt Accessions	Q8VCQ3, Q9DCG3	Gene names	Nrbf2
Domain Architecture	No domain graphic available
Description	Nuclear receptor-binding factor 2 (NRBF-2).

PCNT_HUMAN
θ value	0.365318 (rank : 1562)	NC score	0.064211 (rank : 1355)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1551	Shared Neighborhood Hits	529
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

PRP40_MOUSE
θ value	0.365318 (rank : 1563)	NC score	0.034008 (rank : 1948)
Query Neighborhood Hits	2923	Target Neighborhood Hits	447	Shared Neighborhood Hits	208
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

RBCC1_HUMAN
θ value	0.365318 (rank : 1564)	NC score	0.061168 (rank : 1410)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1023	Shared Neighborhood Hits	401
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

RC3H1_HUMAN
θ value	0.365318 (rank : 1565)	NC score	0.009733 (rank : 2479)
Query Neighborhood Hits	2923	Target Neighborhood Hits	433	Shared Neighborhood Hits	132
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

RL1D1_HUMAN
θ value	0.365318 (rank : 1566)	NC score	0.046241 (rank : 1748)
Query Neighborhood Hits	2923	Target Neighborhood Hits	180	Shared Neighborhood Hits	111
SwissProt Accessions	O76021, Q6PL22, Q8IWS7, Q8WUZ1, Q9HDA9, Q9Y3Z9	Gene names	RSL1D1, CATX11, CSIG, PBK1
Domain Architecture	No domain graphic available
Description	Ribosomal L1 domain-containing protein 1 (Cellular senescence- inhibited gene protein) (Protein PBK1) (CATX-11).

RT35_HUMAN
θ value	0.365318 (rank : 1567)	NC score	0.018682 (rank : 2224)
Query Neighborhood Hits	2923	Target Neighborhood Hits	73	Shared Neighborhood Hits	39
SwissProt Accessions	P82673, Q32LZ1, Q6P4C6, Q7L1M6, Q96AI0, Q9H044, Q9HC14, Q9P1R5	Gene names	MRPS35, MRPS28
Domain Architecture	No domain graphic available
Description	28S ribosomal protein S35, mitochondrial precursor (S35mt) (MRP-S35) (Mitochondrial ribosomal protein S28) (MRP-S28).

SEM4D_MOUSE
θ value	0.365318 (rank : 1568)	NC score	0.019579 (rank : 2214)
Query Neighborhood Hits	2923	Target Neighborhood Hits	143	Shared Neighborhood Hits	65
SwissProt Accessions	O09126	Gene names	Sema4d, Semacl2, Semaj
Domain Architecture
Description	Semaphorin-4D precursor (Semaphorin J) (Sema J) (Semaphorin C-like 2) (M-Sema G).

SETBP_MOUSE
θ value	0.365318 (rank : 1569)	NC score	0.034990 (rank : 1930)
Query Neighborhood Hits	2923	Target Neighborhood Hits	352	Shared Neighborhood Hits	163
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

SMPX_HUMAN
θ value	0.365318 (rank : 1570)	NC score	0.019733 (rank : 2209)
Query Neighborhood Hits	2923	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UHP9	Gene names	SMPX, SRMX
Domain Architecture	No domain graphic available
Description	Small muscular protein (Stretch-responsive skeletal muscle protein).

SNPC4_HUMAN
θ value	0.365318 (rank : 1571)	NC score	0.036652 (rank : 1897)
Query Neighborhood Hits	2923	Target Neighborhood Hits	589	Shared Neighborhood Hits	233
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

TPM1_MOUSE
θ value	0.365318 (rank : 1572)	NC score	0.048709 (rank : 1722)
Query Neighborhood Hits	2923	Target Neighborhood Hits	729	Shared Neighborhood Hits	313
SwissProt Accessions	P58771, P02558, P19354, P46902, P99034	Gene names	Tpm1, Tpm-1, Tpma
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

TPSNR_HUMAN
θ value	0.365318 (rank : 1573)	NC score	0.097216 (rank : 1211)
Query Neighborhood Hits	2923	Target Neighborhood Hits	330	Shared Neighborhood Hits	161
SwissProt Accessions	Q9BX59, Q9NWB8	Gene names	TAPBPL
Domain Architecture	No domain graphic available
Description	Tapasin-related protein precursor (TAPASIN-R) (Tapasin-like) (TAP- binding protein-related protein) (TAPBP-R) (TAP-binding protein-like).

TPX2_HUMAN
θ value	0.365318 (rank : 1574)	NC score	0.033807 (rank : 1952)
Query Neighborhood Hits	2923	Target Neighborhood Hits	150	Shared Neighborhood Hits	92
SwissProt Accessions	Q9ULW0, Q9H1R4, Q9NRA3, Q9UFN9, Q9UL00, Q9Y2M1	Gene names	TPX2, C20orf1, C20orf2, DIL2, HCA519
Domain Architecture	No domain graphic available
Description	Targeting protein for Xklp2 (Restricted expression proliferation- associated protein 100) (p100) (Differentially expressed in cancerous and noncancerous lung cells 2) (DIL-2) (Protein FLS353) (Hepatocellular carcinoma-associated antigen 519).

TRI17_MOUSE
θ value	0.365318 (rank : 1575)	NC score	0.011469 (rank : 2427)
Query Neighborhood Hits	2923	Target Neighborhood Hits	620	Shared Neighborhood Hits	263
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

YETS2_MOUSE
θ value	0.365318 (rank : 1576)	NC score	0.023575 (rank : 2134)
Query Neighborhood Hits	2923	Target Neighborhood Hits	278	Shared Neighborhood Hits	108
SwissProt Accessions	Q3TUF7, Q6PGF8, Q80TI2, Q8CG86	Gene names	Yeats2, Kiaa1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

ZN365_MOUSE
θ value	0.365318 (rank : 1577)	NC score	0.026626 (rank : 2073)
Query Neighborhood Hits	2923	Target Neighborhood Hits	193	Shared Neighborhood Hits	115
SwissProt Accessions	Q8BG89, Q80TQ4, Q8BK39, Q8BXT2	Gene names	Znf365, Kiaa0844, Zfp365
Domain Architecture	No domain graphic available
Description	Protein ZNF365 (Su48).

ZN406_MOUSE
θ value	0.365318 (rank : 1578)	NC score	-0.028424 (rank : 3100)
Query Neighborhood Hits	2923	Target Neighborhood Hits	800	Shared Neighborhood Hits	83
SwissProt Accessions	Q7TS63	Gene names	Znf406, Zfp406
Domain Architecture	No domain graphic available
Description	Zinc finger protein 406.

ZN516_MOUSE
θ value	0.365318 (rank : 1579)	NC score	-0.022251 (rank : 3084)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1197	Shared Neighborhood Hits	225
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

2DOB_HUMAN
θ value	0.47712 (rank : 1580)	NC score	0.000925 (rank : 2807)
Query Neighborhood Hits	2923	Target Neighborhood Hits	201	Shared Neighborhood Hits	48
SwissProt Accessions	P13765, Q29746, Q29825	Gene names	HLA-DOB
Domain Architecture
Description	HLA class II histocompatibility antigen, DO beta chain precursor (MHC class II antigen DOB).

A1BG_HUMAN
θ value	0.47712 (rank : 1581)	NC score	0.080419 (rank : 1262)
Query Neighborhood Hits	2923	Target Neighborhood Hits	94	Shared Neighborhood Hits	66
SwissProt Accessions	P04217, Q8IYJ6, Q96P39	Gene names	A1BG
Domain Architecture
Description	Alpha-1B-glycoprotein precursor (Alpha-1-B glycoprotein).

ACINU_MOUSE
θ value	0.47712 (rank : 1582)	NC score	0.075296 (rank : 1279)
Query Neighborhood Hits	2923	Target Neighborhood Hits	712	Shared Neighborhood Hits	375
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

ADDB_HUMAN
θ value	0.47712 (rank : 1583)	NC score	0.026072 (rank : 2086)
Query Neighborhood Hits	2923	Target Neighborhood Hits	142	Shared Neighborhood Hits	72
SwissProt Accessions	P35612, Q13482, Q16412, Q59G82, Q5U5P4, Q6P0P2, Q6PGQ4, Q7Z688, Q7Z689, Q7Z690, Q7Z691	Gene names	ADD2, ADDB
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta).

AIM2_HUMAN
θ value	0.47712 (rank : 1584)	NC score	0.006501 (rank : 2590)
Query Neighborhood Hits	2923	Target Neighborhood Hits	34	Shared Neighborhood Hits	10
SwissProt Accessions	O14862	Gene names	AIM2
Domain Architecture
Description	Interferon-inducible protein AIM2 (Absent in melanoma 2).

APBA2_HUMAN
θ value	0.47712 (rank : 1585)	NC score	0.008129 (rank : 2533)
Query Neighborhood Hits	2923	Target Neighborhood Hits	220	Shared Neighborhood Hits	50
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

ARHG1_HUMAN
θ value	0.47712 (rank : 1586)	NC score	0.004069 (rank : 2675)
Query Neighborhood Hits	2923	Target Neighborhood Hits	176	Shared Neighborhood Hits	51
SwissProt Accessions	Q92888, O00513, Q8N4J4, Q96BF4, Q96F17, Q9BSB1	Gene names	ARHGEF1
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide exchange factor) (Sub1.5).

BAG3_MOUSE
θ value	0.47712 (rank : 1587)	NC score	0.035423 (rank : 1921)
Query Neighborhood Hits	2923	Target Neighborhood Hits	513	Shared Neighborhood Hits	229
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

BCAR1_MOUSE
θ value	0.47712 (rank : 1588)	NC score	0.029942 (rank : 2001)
Query Neighborhood Hits	2923	Target Neighborhood Hits	438	Shared Neighborhood Hits	155
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

BPAEA_MOUSE
θ value	0.47712 (rank : 1589)	NC score	0.055694 (rank : 1564)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1480	Shared Neighborhood Hits	515
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CABYR_MOUSE
θ value	0.47712 (rank : 1590)	NC score	0.020061 (rank : 2204)
Query Neighborhood Hits	2923	Target Neighborhood Hits	80	Shared Neighborhood Hits	33
SwissProt Accessions	Q9D424, Q91Y41, Q91Y42	Gene names	Cabyr, Cbp86
Domain Architecture	No domain graphic available
Description	Calcium-binding tyrosine phosphorylation-regulated protein (Calcium- binding protein 86) (Testis-specific calcium-binding protein CBP86).

CBL_HUMAN
θ value	0.47712 (rank : 1591)	NC score	0.007162 (rank : 2566)
Query Neighborhood Hits	2923	Target Neighborhood Hits	353	Shared Neighborhood Hits	85
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CCD60_HUMAN
θ value	0.47712 (rank : 1592)	NC score	0.016780 (rank : 2270)
Query Neighborhood Hits	2923	Target Neighborhood Hits	21	Shared Neighborhood Hits	13
SwissProt Accessions	Q8IWA6	Gene names	CCDC60
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 60.

CD226_HUMAN
θ value	0.47712 (rank : 1593)	NC score	0.087453 (rank : 1242)
Query Neighborhood Hits	2923	Target Neighborhood Hits	87	Shared Neighborhood Hits	79
SwissProt Accessions	Q15762	Gene names	CD226, DNAM1
Domain Architecture
Description	CD226 antigen precursor (DNAX accessory molecule 1) (DNAM-1).

CD48_MOUSE
θ value	0.47712 (rank : 1594)	NC score	0.102960 (rank : 1201)
Query Neighborhood Hits	2923	Target Neighborhood Hits	96	Shared Neighborhood Hits	80
SwissProt Accessions	P18181, Q545K2	Gene names	Cd48, Bcm-1
Domain Architecture
Description	CD48 antigen precursor (MRC OX-45 surface antigen) (BCM1 surface antigen) (BLAST-1) (HM48-1) (sgp-60).

CHD9_HUMAN
θ value	0.47712 (rank : 1595)	NC score	0.008344 (rank : 2527)
Query Neighborhood Hits	2923	Target Neighborhood Hits	343	Shared Neighborhood Hits	130
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

CHMP6_MOUSE
θ value	0.47712 (rank : 1596)	NC score	0.019496 (rank : 2215)
Query Neighborhood Hits	2923	Target Neighborhood Hits	99	Shared Neighborhood Hits	42
SwissProt Accessions	P0C0A3	Gene names	Chmp6
Domain Architecture	No domain graphic available
Description	Charged multivesicular body protein 6 (Chromatin-modifying protein 6).

CLGN_MOUSE
θ value	0.47712 (rank : 1597)	NC score	0.012549 (rank : 2399)
Query Neighborhood Hits	2923	Target Neighborhood Hits	142	Shared Neighborhood Hits	55
SwissProt Accessions	P52194, Q9D2K5	Gene names	Clgn, Meg1
Domain Architecture
Description	Calmegin precursor (MEG 1 antigen) (Calnexin-T) (A2/6).

CN045_HUMAN
θ value	0.47712 (rank : 1598)	NC score	0.036662 (rank : 1896)
Query Neighborhood Hits	2923	Target Neighborhood Hits	227	Shared Neighborhood Hits	113
SwissProt Accessions	Q8ND07, Q9H5P8	Gene names	C14orf45
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf45.

CO6A3_HUMAN
θ value	0.47712 (rank : 1599)	NC score	0.019698 (rank : 2210)
Query Neighborhood Hits	2923	Target Neighborhood Hits	317	Shared Neighborhood Hits	99
SwissProt Accessions	P12111, Q16501	Gene names	COL6A3
Domain Architecture
Description	Collagen alpha-3(VI) chain precursor.

CR034_HUMAN
θ value	0.47712 (rank : 1600)	NC score	0.052708 (rank : 1643)
Query Neighborhood Hits	2923	Target Neighborhood Hits	538	Shared Neighborhood Hits	247
SwissProt Accessions	Q5BJE1, Q6ZP67, Q6ZU20	Gene names	C18orf34
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34.

CUTL1_HUMAN
θ value	0.47712 (rank : 1601)	NC score	0.054731 (rank : 1584)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1574	Shared Neighborhood Hits	535
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

EP15_HUMAN
θ value	0.47712 (rank : 1602)	NC score	0.040406 (rank : 1840)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1021	Shared Neighborhood Hits	376
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

EVPL_MOUSE
θ value	0.47712 (rank : 1603)	NC score	0.053736 (rank : 1623)
Query Neighborhood Hits	2923	Target Neighborhood Hits	952	Shared Neighborhood Hits	363
SwissProt Accessions	Q9D952	Gene names	Evpl
Domain Architecture
Description	Envoplakin (p210) (210 kDa cornified envelope precursor protein).

HIP1_HUMAN
θ value	0.47712 (rank : 1604)	NC score	0.057709 (rank : 1500)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1016	Shared Neighborhood Hits	399
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

HPLN4_HUMAN
θ value	0.47712 (rank : 1605)	NC score	0.036354 (rank : 1900)
Query Neighborhood Hits	2923	Target Neighborhood Hits	100	Shared Neighborhood Hits	84
SwissProt Accessions	Q86UW8, Q96PW2	Gene names	HAPLN4, BRAL2, KIAA1926
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 4 precursor (Brain link protein 2).

IL2RG_MOUSE
θ value	0.47712 (rank : 1606)	NC score	0.024304 (rank : 2123)
Query Neighborhood Hits	2923	Target Neighborhood Hits	42	Shared Neighborhood Hits	25
SwissProt Accessions	P34902	Gene names	Il2rg
Domain Architecture
Description	Cytokine receptor common gamma chain precursor (Gamma-C) (Interleukin- 2 receptor gamma chain) (IL-2R gamma chain) (p64) (CD132 antigen).

ITSN1_MOUSE
θ value	0.47712 (rank : 1607)	NC score	0.063862 (rank : 1360)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1669	Shared Neighborhood Hits	593
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

K0562_MOUSE
θ value	0.47712 (rank : 1608)	NC score	0.014674 (rank : 2335)
Query Neighborhood Hits	2923	Target Neighborhood Hits	86	Shared Neighborhood Hits	39
SwissProt Accessions	Q80V31, Q6ZQ95	Gene names	Kiaa0562
Domain Architecture	No domain graphic available
Description	Protein KIAA0562.

K2002_HUMAN
θ value	0.47712 (rank : 1609)	NC score	0.279858 (rank : 1015)
Query Neighborhood Hits	2923	Target Neighborhood Hits	274	Shared Neighborhood Hits	261
SwissProt Accessions	Q9H792, Q6ZS78, Q8NCM3	Gene names	KIAA2002
Domain Architecture	No domain graphic available
Description	Uncharacterized tyrosine-protein kinase KIAA2002 (EC 2.7.10.2).

KC1G2_MOUSE
θ value	0.47712 (rank : 1610)	NC score	0.514460 (rank : 825)
Query Neighborhood Hits	2923	Target Neighborhood Hits	695	Shared Neighborhood Hits	680
SwissProt Accessions	Q8BVP5	Gene names	Csnk1g2
Domain Architecture	No domain graphic available
Description	Casein kinase I isoform gamma-2 (EC 2.7.11.1) (CKI-gamma 2).

LMNA_HUMAN
θ value	0.47712 (rank : 1611)	NC score	0.028332 (rank : 2042)
Query Neighborhood Hits	2923	Target Neighborhood Hits	653	Shared Neighborhood Hits	299
SwissProt Accessions	P02545, P02546, Q969I8, Q96JA2	Gene names	LMNA, LMN1
Domain Architecture
Description	Lamin-A/C (70 kDa lamin) (NY-REN-32 antigen).

LV3B_HUMAN
θ value	0.47712 (rank : 1612)	NC score	0.004149 (rank : 2671)
Query Neighborhood Hits	2923	Target Neighborhood Hits	232	Shared Neighborhood Hits	81
SwissProt Accessions	P80748	Gene names
Domain Architecture	No domain graphic available
Description	Ig lambda chain V-III region LOI.

MAVS_HUMAN
θ value	0.47712 (rank : 1613)	NC score	0.041335 (rank : 1825)
Query Neighborhood Hits	2923	Target Neighborhood Hits	271	Shared Neighborhood Hits	125
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

MED6_HUMAN
θ value	0.47712 (rank : 1614)	NC score	0.018389 (rank : 2229)
Query Neighborhood Hits	2923	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	O75586, O15401, Q9BTH1, Q9UHL1	Gene names	MED6, ARC33
Domain Architecture
Description	RNA polymerase transcriptional regulation mediator, subunit 6 homolog (Activator-recruited cofactor 33 kDa component) (ARC33) (NY-REN-28 antigen).

MOG_MOUSE
θ value	0.47712 (rank : 1615)	NC score	0.050117 (rank : 1702)
Query Neighborhood Hits	2923	Target Neighborhood Hits	102	Shared Neighborhood Hits	84
SwissProt Accessions	Q61885, P70364, Q62003	Gene names	Mog
Domain Architecture
Description	Myelin-oligodendrocyte glycoprotein precursor.

MOX2R_HUMAN
θ value	0.47712 (rank : 1616)	NC score	0.099743 (rank : 1204)
Query Neighborhood Hits	2923	Target Neighborhood Hits	51	Shared Neighborhood Hits	51
SwissProt Accessions	Q8TD46, Q8TD44, Q8TD45, Q8TD52	Gene names	CD200R1, CD200R, CRTR2, MOX2R, OX2R
Domain Architecture	No domain graphic available
Description	Cell surface glycoprotein OX2 receptor precursor (CD200 cell surface glycoprotein receptor).

MTSS1_MOUSE
θ value	0.47712 (rank : 1617)	NC score	0.032869 (rank : 1972)
Query Neighborhood Hits	2923	Target Neighborhood Hits	592	Shared Neighborhood Hits	215
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

MYO5A_MOUSE
θ value	0.47712 (rank : 1618)	NC score	0.054259 (rank : 1603)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1117	Shared Neighborhood Hits	437
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

NIN_MOUSE
θ value	0.47712 (rank : 1619)	NC score	0.056848 (rank : 1537)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1376	Shared Neighborhood Hits	440
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

NOP5_HUMAN
θ value	0.47712 (rank : 1620)	NC score	0.021385 (rank : 2175)
Query Neighborhood Hits	2923	Target Neighborhood Hits	84	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y2X3, Q6PK08, Q9P036, Q9UFN3	Gene names	NOP5
Domain Architecture
Description	Nucleolar protein NOP5 (Nucleolar protein 5) (NOP58).

NP1L4_MOUSE
θ value	0.47712 (rank : 1621)	NC score	0.005411 (rank : 2614)
Query Neighborhood Hits	2923	Target Neighborhood Hits	41	Shared Neighborhood Hits	13
SwissProt Accessions	Q78ZA7, O88701	Gene names	Nap1l4
Domain Architecture	No domain graphic available
Description	Nucleosome assembly protein 1-like 4.

PDCD1_HUMAN
θ value	0.47712 (rank : 1622)	NC score	0.022997 (rank : 2146)
Query Neighborhood Hits	2923	Target Neighborhood Hits	106	Shared Neighborhood Hits	46
SwissProt Accessions	Q15116, O00517	Gene names	PDCD1, PD1
Domain Architecture
Description	Programmed cell death protein 1 precursor (Protein PD-1) (hPD-1) (CD279 antigen).

PGCA_MOUSE
θ value	0.47712 (rank : 1623)	NC score	0.026992 (rank : 2063)
Query Neighborhood Hits	2923	Target Neighborhood Hits	643	Shared Neighborhood Hits	198
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

PML_HUMAN
θ value	0.47712 (rank : 1624)	NC score	0.013884 (rank : 2363)
Query Neighborhood Hits	2923	Target Neighborhood Hits	248	Shared Neighborhood Hits	82
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

PTPRN_HUMAN
θ value	0.47712 (rank : 1625)	NC score	0.045955 (rank : 1752)
Query Neighborhood Hits	2923	Target Neighborhood Hits	156	Shared Neighborhood Hits	56
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

RAI1_HUMAN
θ value	0.47712 (rank : 1626)	NC score	0.022180 (rank : 2167)
Query Neighborhood Hits	2923	Target Neighborhood Hits	360	Shared Neighborhood Hits	137
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

REST_MOUSE
θ value	0.47712 (rank : 1627)	NC score	0.057544 (rank : 1505)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1506	Shared Neighborhood Hits	496
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

RIPK3_HUMAN
θ value	0.47712 (rank : 1628)	NC score	0.620156 (rank : 599)
Query Neighborhood Hits	2923	Target Neighborhood Hits	828	Shared Neighborhood Hits	764
SwissProt Accessions	Q9Y572	Gene names	RIPK3, RIP3
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3).

RM40_MOUSE
θ value	0.47712 (rank : 1629)	NC score	0.014561 (rank : 2340)
Query Neighborhood Hits	2923	Target Neighborhood Hits	30	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Z2Q5, Q9CS52	Gene names	Mrpl40, Nlvcf
Domain Architecture	No domain graphic available
Description	39S ribosomal protein L40, mitochondrial precursor (L40mt) (MRP-40) (Nuclear localization signal-containing protein deleted in velocardiofacial syndrome homolog).

SF04_HUMAN
θ value	0.47712 (rank : 1630)	NC score	0.011259 (rank : 2433)
Query Neighborhood Hits	2923	Target Neighborhood Hits	83	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IWZ8, O60378, Q6P3X9, Q8TCQ4, Q8WWT4, Q8WWT5, Q9NTG3	Gene names	SF4
Domain Architecture	No domain graphic available
Description	Splicing factor 4 (RNA-binding protein RBP).

SLAF7_MOUSE
θ value	0.47712 (rank : 1631)	NC score	0.035790 (rank : 1911)
Query Neighborhood Hits	2923	Target Neighborhood Hits	46	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BHK6, Q8BTL2, Q8CJ63, Q8CJ64, Q8CJ65, Q91XA0	Gene names	Slamf7
Domain Architecture	No domain graphic available
Description	SLAM family member 7 precursor (Leukocyte cell-surface antigen) (Novel Ly9).

SMP1L_HUMAN
θ value	0.47712 (rank : 1632)	NC score	0.001457 (rank : 2782)
Query Neighborhood Hits	2923	Target Neighborhood Hits	74	Shared Neighborhood Hits	24
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

SOX13_MOUSE
θ value	0.47712 (rank : 1633)	NC score	0.012468 (rank : 2404)
Query Neighborhood Hits	2923	Target Neighborhood Hits	495	Shared Neighborhood Hits	166
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

SPESP_MOUSE
θ value	0.47712 (rank : 1634)	NC score	0.014522 (rank : 2342)
Query Neighborhood Hits	2923	Target Neighborhood Hits	20	Shared Neighborhood Hits	11
SwissProt Accessions	Q9D5A0, Q9D5X8	Gene names	Spesp1
Domain Architecture	No domain graphic available
Description	Sperm equatorial segment protein 1 precursor.

SVIL_HUMAN
θ value	0.47712 (rank : 1635)	NC score	0.020603 (rank : 2191)
Query Neighborhood Hits	2923	Target Neighborhood Hits	232	Shared Neighborhood Hits	104
SwissProt Accessions	O95425, O60611, O60612, Q5VZK5, Q5VZK6, Q9H1R7	Gene names	SVIL
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

SYCP3_HUMAN
θ value	0.47712 (rank : 1636)	NC score	0.035460 (rank : 1919)
Query Neighborhood Hits	2923	Target Neighborhood Hits	276	Shared Neighborhood Hits	154
SwissProt Accessions	Q8IZU3	Gene names	SYCP3, SCP3
Domain Architecture	No domain graphic available
Description	Synaptonemal complex protein 3 (SCP-3).

TACC2_MOUSE
θ value	0.47712 (rank : 1637)	NC score	0.061887 (rank : 1396)
Query Neighborhood Hits	2923	Target Neighborhood Hits	774	Shared Neighborhood Hits	386
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

TARA_HUMAN
θ value	0.47712 (rank : 1638)	NC score	0.077341 (rank : 1274)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1626	Shared Neighborhood Hits	619
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TAXB1_HUMAN
θ value	0.47712 (rank : 1639)	NC score	0.058935 (rank : 1469)
Query Neighborhood Hits	2923	Target Neighborhood Hits	829	Shared Neighborhood Hits	355
SwissProt Accessions	Q86VP1, O60398, O95770, Q13311, Q9BQG5, Q9UI88	Gene names	TAX1BP1, T6BP
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 (TRAF6-binding protein).

TCOF_HUMAN
θ value	0.47712 (rank : 1640)	NC score	0.063378 (rank : 1367)
Query Neighborhood Hits	2923	Target Neighborhood Hits	543	Shared Neighborhood Hits	238
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

TCRG1_MOUSE
θ value	0.47712 (rank : 1641)	NC score	0.074286 (rank : 1283)
Query Neighborhood Hits	2923	Target Neighborhood Hits	947	Shared Neighborhood Hits	470
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

TPM1_HUMAN
θ value	0.47712 (rank : 1642)	NC score	0.047392 (rank : 1735)
Query Neighborhood Hits	2923	Target Neighborhood Hits	716	Shared Neighborhood Hits	305
SwissProt Accessions	P09493, P09494, P10469, Q86W64, Q96IK2, Q9UCY9	Gene names	TPM1, TMSA
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

TUFT1_HUMAN
θ value	0.47712 (rank : 1643)	NC score	0.054019 (rank : 1614)
Query Neighborhood Hits	2923	Target Neighborhood Hits	686	Shared Neighborhood Hits	302
SwissProt Accessions	Q9NNX1, Q5T384, Q5T385, Q9BU28, Q9H5L1	Gene names	TUFT1
Domain Architecture	No domain graphic available
Description	Tuftelin.

ZEP2_MOUSE
θ value	0.47712 (rank : 1644)	NC score	-0.018794 (rank : 3080)
Query Neighborhood Hits	2923	Target Neighborhood Hits	964	Shared Neighborhood Hits	163
SwissProt Accessions	Q3UHF7, O55140, Q3UVD4, Q3UVH5	Gene names	Hivep2, Mibp1
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 homolog (Myc intron-binding protein 1) (MIBP-1).

ZHX2_MOUSE
θ value	0.47712 (rank : 1645)	NC score	0.001347 (rank : 2787)
Query Neighborhood Hits	2923	Target Neighborhood Hits	435	Shared Neighborhood Hits	74
SwissProt Accessions	Q8C0C0	Gene names	Zhx2, Afr1, Raf
Domain Architecture
Description	Zinc fingers and homeoboxes protein 2 (Zinc finger and homeodomain protein 2) (Alpha-fetoprotein regulator 1) (AFP regulator 1) (Regulator of AFP).

ZSWM3_HUMAN
θ value	0.47712 (rank : 1646)	NC score	0.006999 (rank : 2573)
Query Neighborhood Hits	2923	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q96MP5, Q9BR13	Gene names	ZSWIM3, C20orf164
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 3.

AMGO1_HUMAN
θ value	0.62314 (rank : 1647)	NC score	0.064642 (rank : 1347)
Query Neighborhood Hits	2923	Target Neighborhood Hits	353	Shared Neighborhood Hits	140
SwissProt Accessions	Q86WK6, Q8IW71, Q9ULQ7	Gene names	AMIGO1, ALI2, AMIGO, KIAA1163
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 1 precursor (AMIGO-1) (Alivin-2).

ANR26_MOUSE
θ value	0.62314 (rank : 1648)	NC score	0.051817 (rank : 1664)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1554	Shared Neighborhood Hits	478
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

ASTN_HUMAN
θ value	0.62314 (rank : 1649)	NC score	0.013235 (rank : 2378)
Query Neighborhood Hits	2923	Target Neighborhood Hits	105	Shared Neighborhood Hits	23
SwissProt Accessions	O14525, O60799, Q5W0V7, Q5W0V8	Gene names	ASTN, ASTN1, KIAA0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor.

ASXL1_HUMAN
θ value	0.62314 (rank : 1650)	NC score	0.026317 (rank : 2081)
Query Neighborhood Hits	2923	Target Neighborhood Hits	260	Shared Neighborhood Hits	98
SwissProt Accessions	Q8IXJ9, Q5JWS9, Q8IYY7, Q9H466, Q9NQF8, Q9UFJ0, Q9UFP8, Q9Y2I4	Gene names	ASXL1, KIAA0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

ATF2_HUMAN
θ value	0.62314 (rank : 1651)	NC score	0.015110 (rank : 2316)
Query Neighborhood Hits	2923	Target Neighborhood Hits	402	Shared Neighborhood Hits	111
SwissProt Accessions	P15336, Q13000	Gene names	ATF2, CREB2, CREBP1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (HB16).

ATF2_MOUSE
θ value	0.62314 (rank : 1652)	NC score	0.014049 (rank : 2356)
Query Neighborhood Hits	2923	Target Neighborhood Hits	397	Shared Neighborhood Hits	108
SwissProt Accessions	P16951, Q64089, Q64090, Q64091	Gene names	Atf2
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (MXBP protein).

BSN_MOUSE
θ value	0.62314 (rank : 1653)	NC score	0.080492 (rank : 1261)
Query Neighborhood Hits	2923	Target Neighborhood Hits	2057	Shared Neighborhood Hits	691
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CCD21_MOUSE
θ value	0.62314 (rank : 1654)	NC score	0.067709 (rank : 1325)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1135	Shared Neighborhood Hits	464
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CD48_HUMAN
θ value	0.62314 (rank : 1655)	NC score	0.084112 (rank : 1252)
Query Neighborhood Hits	2923	Target Neighborhood Hits	64	Shared Neighborhood Hits	55
SwissProt Accessions	P09326	Gene names	CD48, BCM1, BLAST1
Domain Architecture	No domain graphic available
Description	CD48 antigen precursor (B-lymphocyte activation marker BLAST-1) (BCM1 surface antigen) (Leukocyte antigen MEM-102) (TCT.1).

CD80_HUMAN
θ value	0.62314 (rank : 1656)	NC score	0.143724 (rank : 1144)
Query Neighborhood Hits	2923	Target Neighborhood Hits	129	Shared Neighborhood Hits	120
SwissProt Accessions	P33681	Gene names	CD80, CD28LG, CD28LG1, LAB7
Domain Architecture
Description	T-lymphocyte activation antigen CD80 precursor (Activation B7-1 antigen) (CTLA-4 counter-receptor B7.1) (B7) (BB1).

CHRD_MOUSE
θ value	0.62314 (rank : 1657)	NC score	0.003764 (rank : 2692)
Query Neighborhood Hits	2923	Target Neighborhood Hits	102	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Z0E2	Gene names	Chrd
Domain Architecture
Description	Chordin precursor.

CIC_HUMAN
θ value	0.62314 (rank : 1658)	NC score	0.038907 (rank : 1858)
Query Neighborhood Hits	2923	Target Neighborhood Hits	992	Shared Neighborhood Hits	344
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CO8A2_MOUSE
θ value	0.62314 (rank : 1659)	NC score	0.009661 (rank : 2482)
Query Neighborhood Hits	2923	Target Neighborhood Hits	273	Shared Neighborhood Hits	81
SwissProt Accessions	P25318, Q68ED0, Q6KAQ4, Q6P1C4	Gene names	Col8a2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(VIII) chain precursor (Endothelial collagen).

DACT1_HUMAN
θ value	0.62314 (rank : 1660)	NC score	0.026904 (rank : 2065)
Query Neighborhood Hits	2923	Target Neighborhood Hits	228	Shared Neighborhood Hits	102
SwissProt Accessions	Q9NYF0, Q86TY0	Gene names	DACT1, DPR1, HNG3
Domain Architecture	No domain graphic available
Description	Dapper homolog 1 (hDPR1) (Heptacellular carcinoma novel gene 3 protein).

DVL2_HUMAN
θ value	0.62314 (rank : 1661)	NC score	0.001281 (rank : 2790)
Query Neighborhood Hits	2923	Target Neighborhood Hits	223	Shared Neighborhood Hits	53
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

ERBB2_MOUSE
θ value	0.62314 (rank : 1662)	NC score	0.548887 (rank : 761)
Query Neighborhood Hits	2923	Target Neighborhood Hits	918	Shared Neighborhood Hits	790
SwissProt Accessions	P70424, Q61525, Q6ZPE0	Gene names	Erbb2, Kiaa3023, Neu
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene).

FA47A_HUMAN
θ value	0.62314 (rank : 1663)	NC score	0.060229 (rank : 1434)
Query Neighborhood Hits	2923	Target Neighborhood Hits	451	Shared Neighborhood Hits	194
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

FCERA_MOUSE
θ value	0.62314 (rank : 1664)	NC score	0.094238 (rank : 1221)
Query Neighborhood Hits	2923	Target Neighborhood Hits	54	Shared Neighborhood Hits	50
SwissProt Accessions	P20489	Gene names	Fcer1a, Fce1a
Domain Architecture
Description	High affinity immunoglobulin epsilon receptor alpha-subunit precursor (FcERI) (IgE Fc receptor, alpha-subunit) (Fc-epsilon RI-alpha).

FOXC2_HUMAN
θ value	0.62314 (rank : 1665)	NC score	-0.004687 (rank : 2969)
Query Neighborhood Hits	2923	Target Neighborhood Hits	236	Shared Neighborhood Hits	63
SwissProt Accessions	Q99958	Gene names	FOXC2, FKHL14, MFH1
Domain Architecture
Description	Forkhead box protein C2 (Forkhead-related protein FKHL14) (Mesenchyme fork head protein 1) (MFH-1 protein) (Transcription factor FKH-14).

GAK12_HUMAN
θ value	0.62314 (rank : 1666)	NC score	0.013008 (rank : 2384)
Query Neighborhood Hits	2923	Target Neighborhood Hits	374	Shared Neighborhood Hits	130
SwissProt Accessions	P63130, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K102 Gag protein) (HERV-K(III) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GHR_MOUSE
θ value	0.62314 (rank : 1667)	NC score	0.024479 (rank : 2119)
Query Neighborhood Hits	2923	Target Neighborhood Hits	43	Shared Neighborhood Hits	29
SwissProt Accessions	P16882, P16590, Q61653, Q6DI66, Q80W86, Q8R1M5, Q920Z3, Q9R264	Gene names	Ghr
Domain Architecture
Description	Growth hormone receptor precursor (GH receptor) (Somatotropin receptor) [Contains: Growth hormone-binding protein (GH-binding protein) (GHBP) (Serum-binding protein)].

GOGA1_MOUSE
θ value	0.62314 (rank : 1668)	NC score	0.060844 (rank : 1418)
Query Neighborhood Hits	2923	Target Neighborhood Hits	994	Shared Neighborhood Hits	396
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

GP179_HUMAN
θ value	0.62314 (rank : 1669)	NC score	0.032169 (rank : 1980)
Query Neighborhood Hits	2923	Target Neighborhood Hits	372	Shared Neighborhood Hits	147
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

H13_HUMAN
θ value	0.62314 (rank : 1670)	NC score	0.017891 (rank : 2238)
Query Neighborhood Hits	2923	Target Neighborhood Hits	61	Shared Neighborhood Hits	31
SwissProt Accessions	P16402	Gene names	HIST1H1D, H1F3
Domain Architecture
Description	Histone H1.3 (Histone H1c).

HCN2_MOUSE
θ value	0.62314 (rank : 1671)	NC score	0.013245 (rank : 2377)
Query Neighborhood Hits	2923	Target Neighborhood Hits	278	Shared Neighborhood Hits	129
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

INCE_HUMAN
θ value	0.62314 (rank : 1672)	NC score	0.074862 (rank : 1282)
Query Neighborhood Hits	2923	Target Neighborhood Hits	978	Shared Neighborhood Hits	425
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

IRBP_HUMAN
θ value	0.62314 (rank : 1673)	NC score	0.007123 (rank : 2568)
Query Neighborhood Hits	2923	Target Neighborhood Hits	17	Shared Neighborhood Hits	7
SwissProt Accessions	P10745	Gene names	RBP3
Domain Architecture
Description	Interphotoreceptor retinoid-binding protein precursor (IRBP) (Interstitial retinol-binding protein).

KIF17_MOUSE
θ value	0.62314 (rank : 1674)	NC score	0.016622 (rank : 2275)
Query Neighborhood Hits	2923	Target Neighborhood Hits	452	Shared Neighborhood Hits	235
SwissProt Accessions	Q99PW8	Gene names	Kif17
Domain Architecture
Description	Kinesin-like protein KIF17 (MmKIF17).

KTN1_MOUSE
θ value	0.62314 (rank : 1675)	NC score	0.062793 (rank : 1379)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1324	Shared Neighborhood Hits	487
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

LIPB1_MOUSE
θ value	0.62314 (rank : 1676)	NC score	0.040751 (rank : 1833)
Query Neighborhood Hits	2923	Target Neighborhood Hits	727	Shared Neighborhood Hits	312
SwissProt Accessions	Q8C8U0, Q69ZN5, Q6GQV3, Q80VB4, Q9CUT7	Gene names	Ppfibp1, Kiaa1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1).

LIRB4_HUMAN
θ value	0.62314 (rank : 1677)	NC score	0.028185 (rank : 2046)
Query Neighborhood Hits	2923	Target Neighborhood Hits	111	Shared Neighborhood Hits	72
SwissProt Accessions	Q8NHJ6, O15468, O75021, Q8N1C7, Q8NHL5	Gene names	LILRB4, ILT3, LIR5
Domain Architecture	No domain graphic available
Description	Leukocyte immunoglobulin-like receptor subfamily B member 4 precursor (Leukocyte immunoglobulin-like receptor 5) (LIR-5) (Immunoglobulin- like transcript 3) (ILT-3) (Monocyte inhibitory receptor HM18) (CD85k antigen).

LMNA_MOUSE
θ value	0.62314 (rank : 1678)	NC score	0.028139 (rank : 2047)
Query Neighborhood Hits	2923	Target Neighborhood Hits	661	Shared Neighborhood Hits	301
SwissProt Accessions	P48678, P11516, P97859, Q3TIH0, Q3TTS8, Q3UCA0, Q3UCJ8, Q91WF2, Q9DC21	Gene names	Lmna, Lmn1
Domain Architecture
Description	Lamin-A/C.

MAGE1_HUMAN
θ value	0.62314 (rank : 1679)	NC score	0.040991 (rank : 1828)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1389	Shared Neighborhood Hits	441
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MYO10_HUMAN
θ value	0.62314 (rank : 1680)	NC score	0.047141 (rank : 1740)
Query Neighborhood Hits	2923	Target Neighborhood Hits	920	Shared Neighborhood Hits	387
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

NFAT5_HUMAN
θ value	0.62314 (rank : 1681)	NC score	0.010462 (rank : 2457)
Query Neighborhood Hits	2923	Target Neighborhood Hits	217	Shared Neighborhood Hits	72
SwissProt Accessions	O94916, O95693, Q9UN18	Gene names	NFAT5, KIAA0827, TONEBP
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T-cell transcription factor NFAT5) (NF-AT5) (Tonicity-responsive enhancer-binding protein) (TonE- binding protein) (TonEBP).

NPBL_MOUSE
θ value	0.62314 (rank : 1682)	NC score	0.052891 (rank : 1638)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1041	Shared Neighborhood Hits	397
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

PGCA_HUMAN
θ value	0.62314 (rank : 1683)	NC score	0.032744 (rank : 1975)
Query Neighborhood Hits	2923	Target Neighborhood Hits	821	Shared Neighborhood Hits	258
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

PODXL_MOUSE
θ value	0.62314 (rank : 1684)	NC score	0.033670 (rank : 1957)
Query Neighborhood Hits	2923	Target Neighborhood Hits	130	Shared Neighborhood Hits	69
SwissProt Accessions	Q9R0M4, Q9ESZ1	Gene names	Podxl, Pclp1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

PRGR_MOUSE
θ value	0.62314 (rank : 1685)	NC score	-0.004987 (rank : 2976)
Query Neighborhood Hits	2923	Target Neighborhood Hits	286	Shared Neighborhood Hits	65
SwissProt Accessions	Q00175	Gene names	Pgr, Nr3c3, Pr
Domain Architecture
Description	Progesterone receptor (PR).

PRP40_HUMAN
θ value	0.62314 (rank : 1686)	NC score	0.033056 (rank : 1967)
Query Neighborhood Hits	2923	Target Neighborhood Hits	442	Shared Neighborhood Hits	202
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

RP1L1_HUMAN
θ value	0.62314 (rank : 1687)	NC score	0.078046 (rank : 1270)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1072	Shared Neighborhood Hits	406
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

RP3A_MOUSE
θ value	0.62314 (rank : 1688)	NC score	0.022290 (rank : 2161)
Query Neighborhood Hits	2923	Target Neighborhood Hits	510	Shared Neighborhood Hits	165
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SELPL_MOUSE
θ value	0.62314 (rank : 1689)	NC score	0.058097 (rank : 1491)
Query Neighborhood Hits	2923	Target Neighborhood Hits	588	Shared Neighborhood Hits	243
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SEM4G_HUMAN
θ value	0.62314 (rank : 1690)	NC score	0.016375 (rank : 2281)
Query Neighborhood Hits	2923	Target Neighborhood Hits	88	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NTN9, Q9HCF3	Gene names	SEMA4G, KIAA1619
Domain Architecture
Description	Semaphorin-4G precursor.

SENP7_HUMAN
θ value	0.62314 (rank : 1691)	NC score	0.014739 (rank : 2331)
Query Neighborhood Hits	2923	Target Neighborhood Hits	97	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BQF6, Q96PS5, Q9C0F6, Q9HBT5	Gene names	SENP7, KIAA1707, SSP2, SUSP2
Domain Architecture
Description	Sentrin-specific protease 7 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP7) (SUMO-1-specific protease 2).

SETD2_HUMAN
θ value	0.62314 (rank : 1692)	NC score	0.022912 (rank : 2148)
Query Neighborhood Hits	2923	Target Neighborhood Hits	412	Shared Neighborhood Hits	180
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SIA7A_MOUSE
θ value	0.62314 (rank : 1693)	NC score	0.008506 (rank : 2523)
Query Neighborhood Hits	2923	Target Neighborhood Hits	203	Shared Neighborhood Hits	79
SwissProt Accessions	Q9QZ39, Q9JJP5	Gene names	St6galnac1, Siat7a
Domain Architecture
Description	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (EC 2.4.99.3) (GalNAc alpha-2,6-sialyltransferase I) (ST6GalNAc I) (Sialyltransferase 7A).

SPR1A_HUMAN
θ value	0.62314 (rank : 1694)	NC score	0.035578 (rank : 1915)
Query Neighborhood Hits	2923	Target Neighborhood Hits	136	Shared Neighborhood Hits	45
SwissProt Accessions	P35321, Q9UDG4	Gene names	SPRR1A
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein IA) (SPR-IA) (SPRK) (19 kDa pancornulin).

SVIL_MOUSE
θ value	0.62314 (rank : 1695)	NC score	0.029912 (rank : 2004)
Query Neighborhood Hits	2923	Target Neighborhood Hits	439	Shared Neighborhood Hits	174
SwissProt Accessions	Q8K4L3	Gene names	Svil
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

TAXB1_MOUSE
θ value	0.62314 (rank : 1696)	NC score	0.057766 (rank : 1497)
Query Neighborhood Hits	2923	Target Neighborhood Hits	886	Shared Neighborhood Hits	363
SwissProt Accessions	Q3UKC1, Q91YT6, Q9CVF0, Q9DC45	Gene names	Tax1bp1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 homolog.

TTC16_HUMAN
θ value	0.62314 (rank : 1697)	NC score	0.021217 (rank : 2179)
Query Neighborhood Hits	2923	Target Neighborhood Hits	417	Shared Neighborhood Hits	142
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

ZN318_HUMAN
θ value	0.62314 (rank : 1698)	NC score	0.041937 (rank : 1814)
Query Neighborhood Hits	2923	Target Neighborhood Hits	497	Shared Neighborhood Hits	258
SwissProt Accessions	Q5VUA4, O94796, Q4G0E4, Q8NEM6, Q9UNU8, Q9Y2W9	Gene names	ZNF318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Endocrine regulatory protein).

ZRF1_MOUSE
θ value	0.62314 (rank : 1699)	NC score	0.041471 (rank : 1822)
Query Neighborhood Hits	2923	Target Neighborhood Hits	414	Shared Neighborhood Hits	195
SwissProt Accessions	P54103	Gene names	Zrf1, Dnajc2
Domain Architecture
Description	Zuotin-related factor 1.

3BP2_HUMAN
θ value	0.813845 (rank : 1700)	NC score	0.024440 (rank : 2120)
Query Neighborhood Hits	2923	Target Neighborhood Hits	296	Shared Neighborhood Hits	116
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

ABCA2_HUMAN
θ value	0.813845 (rank : 1701)	NC score	-0.005113 (rank : 2978)
Query Neighborhood Hits	2923	Target Neighborhood Hits	143	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BZC7	Gene names	ABCA2, ABC2
Domain Architecture
Description	ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2).

AKAP1_MOUSE
θ value	0.813845 (rank : 1702)	NC score	0.012578 (rank : 2397)
Query Neighborhood Hits	2923	Target Neighborhood Hits	198	Shared Neighborhood Hits	71
SwissProt Accessions	O08715, O08714, P97488	Gene names	Akap1, Akap
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein) (S-AKAP).

B2L13_MOUSE
θ value	0.813845 (rank : 1703)	NC score	0.012523 (rank : 2401)
Query Neighborhood Hits	2923	Target Neighborhood Hits	58	Shared Neighborhood Hits	22
SwissProt Accessions	P59017	Gene names	Bcl2l13, Mil1
Domain Architecture	No domain graphic available
Description	Bcl-2-like 13 protein (Protein Mil1) (Bcl-rambo).

B4GN4_MOUSE
θ value	0.813845 (rank : 1704)	NC score	0.004695 (rank : 2652)
Query Neighborhood Hits	2923	Target Neighborhood Hits	129	Shared Neighborhood Hits	36
SwissProt Accessions	Q766D5, Q8CHV2	Gene names	B4galnt4
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 1 (EC 2.4.1.244) (NGalNAc-T1) (Beta- 1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4).

BAT3_HUMAN
θ value	0.813845 (rank : 1705)	NC score	0.025577 (rank : 2097)
Query Neighborhood Hits	2923	Target Neighborhood Hits	490	Shared Neighborhood Hits	167
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

BAT3_MOUSE
θ value	0.813845 (rank : 1706)	NC score	0.028376 (rank : 2040)
Query Neighborhood Hits	2923	Target Neighborhood Hits	518	Shared Neighborhood Hits	179
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

BT2A3_HUMAN
θ value	0.813845 (rank : 1707)	NC score	0.031824 (rank : 1985)
Query Neighborhood Hits	2923	Target Neighborhood Hits	195	Shared Neighborhood Hits	94
SwissProt Accessions	Q96KV6	Gene names	BTN2A3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A3 precursor.

CABYR_HUMAN
θ value	0.813845 (rank : 1708)	NC score	0.021208 (rank : 2180)
Query Neighborhood Hits	2923	Target Neighborhood Hits	87	Shared Neighborhood Hits	39
SwissProt Accessions	O75952, Q8WXW5, Q9HAY3, Q9HAY4, Q9HAY5, Q9HCY9	Gene names	CABYR, CBP86, FSP2
Domain Architecture	No domain graphic available
Description	Calcium-binding tyrosine phosphorylation-regulated protein (Calcium- binding protein 86) (Testis-specific calcium-binding protein CBP86) (Fibrousheathin-2) (FSP-2).

CALX_HUMAN
θ value	0.813845 (rank : 1709)	NC score	0.011069 (rank : 2438)
Query Neighborhood Hits	2923	Target Neighborhood Hits	96	Shared Neighborhood Hits	45
SwissProt Accessions	P27824	Gene names	CANX
Domain Architecture
Description	Calnexin precursor (Major histocompatibility complex class I antigen- binding protein p88) (p90) (IP90).

CASP_HUMAN
θ value	0.813845 (rank : 1710)	NC score	0.057760 (rank : 1499)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1131	Shared Neighborhood Hits	432
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CBP_MOUSE
θ value	0.813845 (rank : 1711)	NC score	0.044285 (rank : 1772)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1051	Shared Neighborhood Hits	407
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CK024_HUMAN
θ value	0.813845 (rank : 1712)	NC score	0.056002 (rank : 1557)
Query Neighborhood Hits	2923	Target Neighborhood Hits	408	Shared Neighborhood Hits	167
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

CLMN_HUMAN
θ value	0.813845 (rank : 1713)	NC score	0.008147 (rank : 2531)
Query Neighborhood Hits	2923	Target Neighborhood Hits	205	Shared Neighborhood Hits	72
SwissProt Accessions	Q96JQ2, Q9H713, Q9HA23, Q9HA57, Q9UFP4, Q9ULN2	Gene names	CLMN, KIAA1188
Domain Architecture
Description	Calmin.

CN145_HUMAN
θ value	0.813845 (rank : 1714)	NC score	0.061103 (rank : 1411)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1196	Shared Neighborhood Hits	455
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

DAF1_MOUSE
θ value	0.813845 (rank : 1715)	NC score	0.000701 (rank : 2816)
Query Neighborhood Hits	2923	Target Neighborhood Hits	204	Shared Neighborhood Hits	68
SwissProt Accessions	Q61475, P97732, Q61397	Gene names	Cd55a, Daf1
Domain Architecture
Description	Complement decay-accelerating factor, GPI-anchored precursor (DAF-GPI) (CD55 antigen).

DHX57_MOUSE
θ value	0.813845 (rank : 1716)	NC score	0.000316 (rank : 2830)
Query Neighborhood Hits	2923	Target Neighborhood Hits	125	Shared Neighborhood Hits	28
SwissProt Accessions	Q6P5D3, Q3TS93, Q6NZK4, Q6P1B4, Q8BI63, Q8BIA2, Q8R360	Gene names	Dhx57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

DLG7_MOUSE
θ value	0.813845 (rank : 1717)	NC score	0.011178 (rank : 2436)
Query Neighborhood Hits	2923	Target Neighborhood Hits	84	Shared Neighborhood Hits	34
SwissProt Accessions	Q8K4R9, Q6ZQL3, Q80VS7, Q8BUC8, Q8BZ79	Gene names	Dlg7, Kiaa0008
Domain Architecture	No domain graphic available
Description	Discs large homolog 7 (Hepatoma up-regulated protein homolog) (HURP).

DNMT1_HUMAN
θ value	0.813845 (rank : 1718)	NC score	0.039222 (rank : 1850)
Query Neighborhood Hits	2923	Target Neighborhood Hits	401	Shared Neighborhood Hits	202
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

FA48A_MOUSE
θ value	0.813845 (rank : 1719)	NC score	0.009480 (rank : 2491)
Query Neighborhood Hits	2923	Target Neighborhood Hits	15	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TT00, Q8BG53, Q9JLS9	Gene names	Fam48a, D3Ertd300e
Domain Architecture	No domain graphic available
Description	Protein FAM48A (p38-interacting protein) (p38IP).

GAK6_HUMAN
θ value	0.813845 (rank : 1720)	NC score	0.014369 (rank : 2346)
Query Neighborhood Hits	2923	Target Neighborhood Hits	392	Shared Neighborhood Hits	142
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GCP60_HUMAN
θ value	0.813845 (rank : 1721)	NC score	0.041917 (rank : 1816)
Query Neighborhood Hits	2923	Target Neighborhood Hits	419	Shared Neighborhood Hits	207
SwissProt Accessions	Q9H3P7, Q5VTJ0, Q6P9F1, Q8IZC5, Q8N4D6, Q9H6U3	Gene names	ACBD3, GCP60
Domain Architecture	No domain graphic available
Description	Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi phosphoprotein 1) (GOLPH1) (Golgi complex-associated protein 1) (GOCAP1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7).

GDE5_MOUSE
θ value	0.813845 (rank : 1722)	NC score	0.006061 (rank : 2601)
Query Neighborhood Hits	2923	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C0L9, Q3TLV6, Q80TD5, Q8BKJ7, Q8BKW7, Q8CFW2, Q9D759	Gene names	Gde5, Kiaa1434, Prei4
Domain Architecture	No domain graphic available
Description	Putative glycerophosphodiester phosphodiesterase 5 (EC 3.1.-.-) (Preimplantation protein 4).

GP73_HUMAN
θ value	0.813845 (rank : 1723)	NC score	0.043039 (rank : 1796)
Query Neighborhood Hits	2923	Target Neighborhood Hits	309	Shared Neighborhood Hits	178
SwissProt Accessions	Q8NBJ4, Q6IAF4, Q9NRB9	Gene names	GOLPH2
Domain Architecture	No domain graphic available
Description	Golgi phosphoprotein 2 (Golgi membrane protein GP73).

HB22_MOUSE
θ value	0.813845 (rank : 1724)	NC score	0.003567 (rank : 2707)
Query Neighborhood Hits	2923	Target Neighborhood Hits	210	Shared Neighborhood Hits	57
SwissProt Accessions	P01915	Gene names
Domain Architecture	No domain graphic available
Description	H-2 class II histocompatibility antigen, E-D beta chain precursor.

HDAC7_HUMAN
θ value	0.813845 (rank : 1725)	NC score	0.003305 (rank : 2714)
Query Neighborhood Hits	2923	Target Neighborhood Hits	64	Shared Neighborhood Hits	22
SwissProt Accessions	Q8WUI4, Q7Z5I1, Q96K01, Q9BR73, Q9H7L0, Q9NW41, Q9NWA9, Q9NYK9, Q9UFU7	Gene names	HDAC7A, HDAC7
Domain Architecture
Description	Histone deacetylase 7a (HD7a).

HDAC7_MOUSE
θ value	0.813845 (rank : 1726)	NC score	0.003822 (rank : 2687)
Query Neighborhood Hits	2923	Target Neighborhood Hits	85	Shared Neighborhood Hits	33
SwissProt Accessions	Q8C2B3, Q8C2C9, Q8C8X4, Q8CB80, Q8CDA3, Q9JL72	Gene names	Hdac7a, Hdac7
Domain Architecture
Description	Histone deacetylase 7a (HD7a).

HMMR_MOUSE
θ value	0.813845 (rank : 1727)	NC score	0.059874 (rank : 1445)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1178	Shared Neighborhood Hits	445
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

HPLN1_MOUSE
θ value	0.813845 (rank : 1728)	NC score	0.020034 (rank : 2205)
Query Neighborhood Hits	2923	Target Neighborhood Hits	64	Shared Neighborhood Hits	50
SwissProt Accessions	Q9QUP5, Q9D1G9, Q9Z1X7	Gene names	Hapln1, Crtl1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 1 precursor (Proteoglycan link protein) (Cartilage link protein) (LP).

IF3A_HUMAN
θ value	0.813845 (rank : 1729)	NC score	0.063939 (rank : 1359)
Query Neighborhood Hits	2923	Target Neighborhood Hits	875	Shared Neighborhood Hits	389
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

IGHA2_HUMAN
θ value	0.813845 (rank : 1730)	NC score	0.035103 (rank : 1928)
Query Neighborhood Hits	2923	Target Neighborhood Hits	184	Shared Neighborhood Hits	62
SwissProt Accessions	P01877	Gene names	IGHA2
Domain Architecture
Description	Ig alpha-2 chain C region.

ITPR1_MOUSE
θ value	0.813845 (rank : 1731)	NC score	0.003581 (rank : 2704)
Query Neighborhood Hits	2923	Target Neighborhood Hits	99	Shared Neighborhood Hits	40
SwissProt Accessions	P11881, P20943, Q99LG5	Gene names	Itpr1, Insp3r, Pcd6, Pcp1
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 1 (Type 1 inositol 1,4,5- trisphosphate receptor) (Type 1 InsP3 receptor) (IP3 receptor isoform 1) (InsP3R1) (Inositol 1,4,5-trisphosphate-binding protein P400) (Purkinje cell protein 1) (Protein PCD-6).

LPP_HUMAN
θ value	0.813845 (rank : 1732)	NC score	0.016668 (rank : 2271)
Query Neighborhood Hits	2923	Target Neighborhood Hits	775	Shared Neighborhood Hits	231
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

LRSM1_HUMAN
θ value	0.813845 (rank : 1733)	NC score	0.041505 (rank : 1821)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1078	Shared Neighborhood Hits	379
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

LV3A_HUMAN
θ value	0.813845 (rank : 1734)	NC score	0.000933 (rank : 2806)
Query Neighborhood Hits	2923	Target Neighborhood Hits	238	Shared Neighborhood Hits	69
SwissProt Accessions	P01714	Gene names
Domain Architecture	No domain graphic available
Description	Ig lambda chain V-III region SH.

MUC5B_HUMAN
θ value	0.813845 (rank : 1735)	NC score	0.049083 (rank : 1717)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1020	Shared Neighborhood Hits	313
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

NOTC2_HUMAN
θ value	0.813845 (rank : 1736)	NC score	0.023518 (rank : 2135)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1113	Shared Neighborhood Hits	232
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

OBF1_MOUSE
θ value	0.813845 (rank : 1737)	NC score	0.022969 (rank : 2147)
Query Neighborhood Hits	2923	Target Neighborhood Hits	73	Shared Neighborhood Hits	27
SwissProt Accessions	Q64693	Gene names	Pou2af1, Obf-1
Domain Architecture	No domain graphic available
Description	POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (OCT-binding factor 1) (BOB-1) (BOB1) (OCA-B).

PACS1_HUMAN
θ value	0.813845 (rank : 1738)	NC score	0.018212 (rank : 2232)
Query Neighborhood Hits	2923	Target Neighborhood Hits	82	Shared Neighborhood Hits	46
SwissProt Accessions	Q6VY07, Q6PJY6, Q6PKB6, Q7Z590, Q7Z5W4, Q8N8K6, Q96MW0, Q9NW92, Q9ULP5	Gene names	PACS1, KIAA1175
Domain Architecture	No domain graphic available
Description	Phosphofurin acidic cluster sorting protein 1 (PACS-1).

PC11Y_HUMAN
θ value	0.813845 (rank : 1739)	NC score	-0.007303 (rank : 3012)
Query Neighborhood Hits	2923	Target Neighborhood Hits	205	Shared Neighborhood Hits	56
SwissProt Accessions	Q9BZA8, Q70LR6, Q70LR8, Q70LS0, Q70LS1, Q70LS2, Q70LS3, Q70LS4, Q70LS5, Q8WY34, Q9BZA9, Q9H4E1	Gene names	PCDH11Y, PCDH11, PCDH22, PCDHY
Domain Architecture	No domain graphic available
Description	Protocadherin-11 Y-linked precursor (Protocadherin-11) (Protocadherin- 22) (Protocadherin on the Y chromosome) (PCDH-Y) (Protocadherin prostate cancer) (Protocadherin-PC).

PDLI7_HUMAN
θ value	0.813845 (rank : 1740)	NC score	0.003446 (rank : 2710)
Query Neighborhood Hits	2923	Target Neighborhood Hits	547	Shared Neighborhood Hits	154
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

PHLB1_MOUSE
θ value	0.813845 (rank : 1741)	NC score	0.046513 (rank : 1746)
Query Neighborhood Hits	2923	Target Neighborhood Hits	678	Shared Neighborhood Hits	302
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PKHA5_HUMAN
θ value	0.813845 (rank : 1742)	NC score	0.029465 (rank : 2014)
Query Neighborhood Hits	2923	Target Neighborhood Hits	455	Shared Neighborhood Hits	202
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

PSL1_HUMAN
θ value	0.813845 (rank : 1743)	NC score	0.027469 (rank : 2055)
Query Neighborhood Hits	2923	Target Neighborhood Hits	650	Shared Neighborhood Hits	210
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

RAI14_HUMAN
θ value	0.813845 (rank : 1744)	NC score	0.038126 (rank : 1874)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1367	Shared Neighborhood Hits	438
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

RFIP1_MOUSE
θ value	0.813845 (rank : 1745)	NC score	0.017256 (rank : 2256)
Query Neighborhood Hits	2923	Target Neighborhood Hits	152	Shared Neighborhood Hits	57
SwissProt Accessions	Q9D620, Q3UBC2, Q8BN24	Gene names	Rab11fip1, Rcp
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

SNTB2_MOUSE
θ value	0.813845 (rank : 1746)	NC score	-0.001299 (rank : 2892)
Query Neighborhood Hits	2923	Target Neighborhood Hits	181	Shared Neighborhood Hits	38
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

SRRM1_HUMAN
θ value	0.813845 (rank : 1747)	NC score	0.096367 (rank : 1218)
Query Neighborhood Hits	2923	Target Neighborhood Hits	690	Shared Neighborhood Hits	323
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SYCP1_HUMAN
θ value	0.813845 (rank : 1748)	NC score	0.060329 (rank : 1431)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1313	Shared Neighborhood Hits	478
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

SYGP1_HUMAN
θ value	0.813845 (rank : 1749)	NC score	0.029142 (rank : 2023)
Query Neighborhood Hits	2923	Target Neighborhood Hits	589	Shared Neighborhood Hits	281
SwissProt Accessions	Q96PV0, Q8TCS2, Q9UGE2	Gene names	SYNGAP1, KIAA1938
Domain Architecture
Description	Ras GTPase-activating protein SynGAP (Synaptic Ras-GTPase-activating protein 1) (Synaptic Ras-GAP 1) (Neuronal RasGAP).

SYUG_HUMAN
θ value	0.813845 (rank : 1750)	NC score	0.013096 (rank : 2381)
Query Neighborhood Hits	2923	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	O76070, O15104, Q96P61	Gene names	SNCG, BCSG1, PERSYN, PRSN
Domain Architecture
Description	Gamma-synuclein (Persyn) (Breast cancer-specific gene 1 protein) (Synoretin) (SR).

TBLX_MOUSE
θ value	0.813845 (rank : 1751)	NC score	-0.016204 (rank : 3076)
Query Neighborhood Hits	2923	Target Neighborhood Hits	335	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QXE7, Q8BMM0, Q8BYQ4, Q8C0A1	Gene names	Tbl1x, Tbl1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1X (Transducin beta-like 1X protein).

TCPE_MOUSE
θ value	0.813845 (rank : 1752)	NC score	-0.000066 (rank : 2841)
Query Neighborhood Hits	2923	Target Neighborhood Hits	37	Shared Neighborhood Hits	7
SwissProt Accessions	P80316	Gene names	Cct5, Ccte
Domain Architecture
Description	T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon).

TF3C4_MOUSE
θ value	0.813845 (rank : 1753)	NC score	0.007766 (rank : 2547)
Query Neighborhood Hits	2923	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BMQ2, Q8BKZ4	Gene names	Gtf3c4
Domain Architecture	No domain graphic available
Description	General transcription factor 3C polypeptide 4 (EC 2.3.1.48) (Transcription factor IIIC subunit delta) (TF3C-delta) (TFIIIC 90 kDa subunit) (TFIIIC 90).

TM110_HUMAN
θ value	0.813845 (rank : 1754)	NC score	0.009228 (rank : 2503)
Query Neighborhood Hits	2923	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q86TL2	Gene names	TMEM110
Domain Architecture	No domain graphic available
Description	Transmembrane protein 110.

TOPK_HUMAN
θ value	0.813845 (rank : 1755)	NC score	0.473467 (rank : 880)
Query Neighborhood Hits	2923	Target Neighborhood Hits	605	Shared Neighborhood Hits	545
SwissProt Accessions	Q96KB5, Q9NPD9, Q9NYL7, Q9NZK6	Gene names	PBK, TOPK
Domain Architecture	No domain graphic available
Description	T-lymphokine-activated killer cell-originated protein kinase (EC 2.7.12.2) (T-LAK cell-originated protein kinase) (PDZ-binding kinase) (Spermatogenesis-related protein kinase) (SPK) (MAPKK-like protein kinase) (Nori-3).

TRHY_HUMAN
θ value	0.813845 (rank : 1756)	NC score	0.070756 (rank : 1305)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1385	Shared Neighborhood Hits	494
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

TSH1_MOUSE
θ value	0.813845 (rank : 1757)	NC score	0.000882 (rank : 2810)
Query Neighborhood Hits	2923	Target Neighborhood Hits	675	Shared Neighborhood Hits	119
SwissProt Accessions	Q5DTH5, Q6PE60, Q8VD19, Q9JLD5	Gene names	Tshz1, Kiaa4206, Sdccag33, Tsh1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3 homolog).

U235_HUMAN
θ value	0.813845 (rank : 1758)	NC score	0.013178 (rank : 2380)
Query Neighborhood Hits	2923	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WUR7	Gene names	C15orf40
Domain Architecture
Description	UPF0235 protein C15orf40.

VDP_HUMAN
θ value	0.813845 (rank : 1759)	NC score	0.046042 (rank : 1750)
Query Neighborhood Hits	2923	Target Neighborhood Hits	645	Shared Neighborhood Hits	282
SwissProt Accessions	O60763	Gene names	VDP
Domain Architecture
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

VPS72_MOUSE
θ value	0.813845 (rank : 1760)	NC score	0.021452 (rank : 2173)
Query Neighborhood Hits	2923	Target Neighborhood Hits	286	Shared Neighborhood Hits	104
SwissProt Accessions	Q62481, Q3U2N4, Q810A9, Q99K81	Gene names	Vps72, Tcfl1, Yl1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

WDTC1_HUMAN
θ value	0.813845 (rank : 1761)	NC score	-0.009141 (rank : 3050)
Query Neighborhood Hits	2923	Target Neighborhood Hits	299	Shared Neighborhood Hits	21
SwissProt Accessions	Q8N5D0, Q9NV87, Q9UPW4	Gene names	WDTC1, KIAA1037
Domain Architecture
Description	WD and tetratricopeptide repeats protein 1.

ZC11A_MOUSE
θ value	0.813845 (rank : 1762)	NC score	0.026459 (rank : 2077)
Query Neighborhood Hits	2923	Target Neighborhood Hits	216	Shared Neighborhood Hits	111
SwissProt Accessions	Q6NZF1, Q6NXW9, Q6PDR6, Q80TU7, Q8C5L5, Q99JN6	Gene names	Zc3h11a, Kiaa0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

ZN217_HUMAN
θ value	0.813845 (rank : 1763)	NC score	-0.023601 (rank : 3088)
Query Neighborhood Hits	2923	Target Neighborhood Hits	905	Shared Neighborhood Hits	142
SwissProt Accessions	O75362	Gene names	ZNF217, ZABC1
Domain Architecture	No domain graphic available
Description	Zinc finger protein 217.

ZN638_HUMAN
θ value	0.813845 (rank : 1764)	NC score	0.026966 (rank : 2064)
Query Neighborhood Hits	2923	Target Neighborhood Hits	343	Shared Neighborhood Hits	163
SwissProt Accessions	Q14966, Q53R34, Q5XJ05, Q68DP3, Q6P2H2, Q7Z3T7, Q8NF92, Q8TCA1, Q9H2G1, Q9NP37	Gene names	ZNF638, NP220, ZFML
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein) (Cutaneous T-cell lymphoma-associated antigen se33-1) (CTCL tumor antigen se33-1).

ALEX_MOUSE
θ value	1.06291 (rank : 1765)	NC score	0.052877 (rank : 1642)
Query Neighborhood Hits	2923	Target Neighborhood Hits	197	Shared Neighborhood Hits	103
SwissProt Accessions	Q6R0H6, Q8BIR3	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

ATF6B_HUMAN
θ value	1.06291 (rank : 1766)	NC score	0.008257 (rank : 2530)
Query Neighborhood Hits	2923	Target Neighborhood Hits	122	Shared Neighborhood Hits	49
SwissProt Accessions	Q99941, Q13269, Q14343, Q14345, Q99635, Q99637, Q9H3V9, Q9H3W1, Q9NPL0	Gene names	CREBL1, G13
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp) (Protein G13).

BIN1_MOUSE
θ value	1.06291 (rank : 1767)	NC score	0.025689 (rank : 2094)
Query Neighborhood Hits	2923	Target Neighborhood Hits	283	Shared Neighborhood Hits	108
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

CAF1A_HUMAN
θ value	1.06291 (rank : 1768)	NC score	0.058900 (rank : 1472)
Query Neighborhood Hits	2923	Target Neighborhood Hits	750	Shared Neighborhood Hits	342
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CCD45_MOUSE
θ value	1.06291 (rank : 1769)	NC score	0.060548 (rank : 1426)
Query Neighborhood Hits	2923	Target Neighborhood Hits	663	Shared Neighborhood Hits	330
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

CD8A_MOUSE
θ value	1.06291 (rank : 1770)	NC score	0.027652 (rank : 2054)
Query Neighborhood Hits	2923	Target Neighborhood Hits	41	Shared Neighborhood Hits	23
SwissProt Accessions	P01731	Gene names	Cd8a, Lyt-2, Lyt2
Domain Architecture
Description	T-cell surface glycoprotein CD8 alpha chain precursor (T-cell surface glycoprotein Lyt-2) (CD8a antigen).

CO4A5_HUMAN
θ value	1.06291 (rank : 1771)	NC score	0.015722 (rank : 2294)
Query Neighborhood Hits	2923	Target Neighborhood Hits	383	Shared Neighborhood Hits	120
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

CROCC_HUMAN
θ value	1.06291 (rank : 1772)	NC score	0.059768 (rank : 1451)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1409	Shared Neighborhood Hits	472
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

CSPG2_MOUSE
θ value	1.06291 (rank : 1773)	NC score	0.017198 (rank : 2259)
Query Neighborhood Hits	2923	Target Neighborhood Hits	711	Shared Neighborhood Hits	189
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

CT072_HUMAN
θ value	1.06291 (rank : 1774)	NC score	0.008277 (rank : 2529)
Query Neighborhood Hits	2923	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BQP7, Q96SW3	Gene names	C20orf72
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf72.

CYLN2_HUMAN
θ value	1.06291 (rank : 1775)	NC score	0.058289 (rank : 1485)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1004	Shared Neighborhood Hits	403
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

DVL2_MOUSE
θ value	1.06291 (rank : 1776)	NC score	0.001347 (rank : 2786)
Query Neighborhood Hits	2923	Target Neighborhood Hits	233	Shared Neighborhood Hits	61
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

FOXP1_MOUSE
θ value	1.06291 (rank : 1777)	NC score	0.000775 (rank : 2815)
Query Neighborhood Hits	2923	Target Neighborhood Hits	241	Shared Neighborhood Hits	97
SwissProt Accessions	P58462	Gene names	Foxp1
Domain Architecture
Description	Forkhead box protein P1 (Forkhead-related transcription factor 1).

GCP60_MOUSE
θ value	1.06291 (rank : 1778)	NC score	0.039126 (rank : 1854)
Query Neighborhood Hits	2923	Target Neighborhood Hits	395	Shared Neighborhood Hits	189
SwissProt Accessions	Q8BMP6, O35371	Gene names	Acbd3, Gcp60, Pap7
Domain Architecture	No domain graphic available
Description	Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi phosphoprotein 1) (GOLPH1) (Golgi complex-associated protein 1) (GOCAP1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7).

GOGA3_MOUSE
θ value	1.06291 (rank : 1779)	NC score	0.057588 (rank : 1504)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1437	Shared Neighborhood Hits	477
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

GON4L_HUMAN
θ value	1.06291 (rank : 1780)	NC score	0.026713 (rank : 2070)
Query Neighborhood Hits	2923	Target Neighborhood Hits	555	Shared Neighborhood Hits	233
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

GOPC_HUMAN
θ value	1.06291 (rank : 1781)	NC score	0.011641 (rank : 2422)
Query Neighborhood Hits	2923	Target Neighborhood Hits	377	Shared Neighborhood Hits	145
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

HERC2_MOUSE
θ value	1.06291 (rank : 1782)	NC score	0.012574 (rank : 2398)
Query Neighborhood Hits	2923	Target Neighborhood Hits	167	Shared Neighborhood Hits	43
SwissProt Accessions	Q4U2R1, O88473, Q3TRJ8, Q3TS47, Q3TST2, Q3UFQ6, Q3URH7, Q5DU32, Q7TPR5, Q80VV7, Q9QYT1, Q9Z168, Q9Z171	Gene names	Herc2, jdf2, Kiaa0393, rjs
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

HPLN4_MOUSE
θ value	1.06291 (rank : 1783)	NC score	0.032640 (rank : 1978)
Query Neighborhood Hits	2923	Target Neighborhood Hits	98	Shared Neighborhood Hits	78
SwissProt Accessions	Q80WM4, Q80XX2	Gene names	Hapln4, Bral2, Lpr4
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 4 precursor (Brain link protein 2) (Link protein 4).

HSP74_HUMAN
θ value	1.06291 (rank : 1784)	NC score	0.011360 (rank : 2431)
Query Neighborhood Hits	2923	Target Neighborhood Hits	154	Shared Neighborhood Hits	78
SwissProt Accessions	P34932, O95756	Gene names	HSPA4
Domain Architecture
Description	Heat shock 70 kDa protein 4 (Heat shock 70-related protein APG-2) (HSP70RY).

HUWE1_HUMAN
θ value	1.06291 (rank : 1785)	NC score	0.012384 (rank : 2405)
Query Neighborhood Hits	2923	Target Neighborhood Hits	443	Shared Neighborhood Hits	163
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

IDS_HUMAN
θ value	1.06291 (rank : 1786)	NC score	0.002474 (rank : 2745)
Query Neighborhood Hits	2923	Target Neighborhood Hits	30	Shared Neighborhood Hits	5
SwissProt Accessions	P22304, Q14604	Gene names	IDS
Domain Architecture
Description	Iduronate 2-sulfatase precursor (EC 3.1.6.13) (Alpha-L-iduronate sulfate sulfatase) (Idursulfase) [Contains: Iduronate 2-sulfatase 42 kDa chain; Iduronate 2-sulfatase 14 kDa chain].

IF4G1_HUMAN
θ value	1.06291 (rank : 1787)	NC score	0.033686 (rank : 1956)
Query Neighborhood Hits	2923	Target Neighborhood Hits	347	Shared Neighborhood Hits	168
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

IGHDM_MOUSE
θ value	1.06291 (rank : 1788)	NC score	0.017814 (rank : 2241)
Query Neighborhood Hits	2923	Target Neighborhood Hits	162	Shared Neighborhood Hits	46
SwissProt Accessions	P01882	Gene names
Domain Architecture	No domain graphic available
Description	Ig delta chain C region membrane-bound form.

IGHD_MOUSE
θ value	1.06291 (rank : 1789)	NC score	0.016455 (rank : 2279)
Query Neighborhood Hits	2923	Target Neighborhood Hits	160	Shared Neighborhood Hits	46
SwissProt Accessions	P01881	Gene names
Domain Architecture	No domain graphic available
Description	Ig delta chain C region secreted form.

IL5RA_MOUSE
θ value	1.06291 (rank : 1790)	NC score	0.013532 (rank : 2369)
Query Neighborhood Hits	2923	Target Neighborhood Hits	33	Shared Neighborhood Hits	18
SwissProt Accessions	P21183	Gene names	Il5ra, Il5r
Domain Architecture	No domain graphic available
Description	Interleukin-5 receptor alpha chain precursor (IL-5R-alpha) (CD125 antigen).

KIF3B_HUMAN
θ value	1.06291 (rank : 1791)	NC score	0.020496 (rank : 2194)
Query Neighborhood Hits	2923	Target Neighborhood Hits	540	Shared Neighborhood Hits	256
SwissProt Accessions	O15066	Gene names	KIF3B, KIAA0359
Domain Architecture
Description	Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B) (HH0048).

KIF9_HUMAN
θ value	1.06291 (rank : 1792)	NC score	0.005115 (rank : 2630)
Query Neighborhood Hits	2923	Target Neighborhood Hits	118	Shared Neighborhood Hits	55
SwissProt Accessions	Q9HAQ2, Q86Z28, Q9H8A4	Gene names	KIF9
Domain Architecture
Description	Kinesin-like protein KIF9.

MAGC1_HUMAN
θ value	1.06291 (rank : 1793)	NC score	0.015263 (rank : 2313)
Query Neighborhood Hits	2923	Target Neighborhood Hits	431	Shared Neighborhood Hits	165
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

MLL2_HUMAN
θ value	1.06291 (rank : 1794)	NC score	0.069025 (rank : 1312)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1788	Shared Neighborhood Hits	644
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MY18A_MOUSE
θ value	1.06291 (rank : 1795)	NC score	0.064219 (rank : 1354)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1989	Shared Neighborhood Hits	618
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MYBB_HUMAN
θ value	1.06291 (rank : 1796)	NC score	0.008777 (rank : 2513)
Query Neighborhood Hits	2923	Target Neighborhood Hits	78	Shared Neighborhood Hits	36
SwissProt Accessions	P10244	Gene names	MYBL2, BMYB
Domain Architecture
Description	Myb-related protein B (B-Myb).

MYH14_HUMAN
θ value	1.06291 (rank : 1797)	NC score	0.049702 (rank : 1711)
Query Neighborhood Hits	2923	Target Neighborhood Hits	995	Shared Neighborhood Hits	345
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

MYH3_HUMAN
θ value	1.06291 (rank : 1798)	NC score	0.054285 (rank : 1601)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1660	Shared Neighborhood Hits	528
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

NALP5_HUMAN
θ value	1.06291 (rank : 1799)	NC score	-0.001640 (rank : 2901)
Query Neighborhood Hits	2923	Target Neighborhood Hits	88	Shared Neighborhood Hits	12
SwissProt Accessions	P59047, Q86W29	Gene names	NALP5, MATER
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Mater protein homolog).

NCOR2_MOUSE
θ value	1.06291 (rank : 1800)	NC score	0.053758 (rank : 1622)
Query Neighborhood Hits	2923	Target Neighborhood Hits	790	Shared Neighborhood Hits	374
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

NIN_HUMAN
θ value	1.06291 (rank : 1801)	NC score	0.059677 (rank : 1454)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1416	Shared Neighborhood Hits	476
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

PCNT_MOUSE
θ value	1.06291 (rank : 1802)	NC score	0.063248 (rank : 1369)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1207	Shared Neighborhood Hits	440
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

PO6F1_MOUSE
θ value	1.06291 (rank : 1803)	NC score	0.002429 (rank : 2748)
Query Neighborhood Hits	2923	Target Neighborhood Hits	581	Shared Neighborhood Hits	150
SwissProt Accessions	Q07916, Q91XK3	Gene names	Pou6f1, Emb
Domain Architecture
Description	POU domain, class 6, transcription factor 1 (Octamer-binding transcription factor EMB) (Transcription regulatory protein MCP-1).

PRD15_HUMAN
θ value	1.06291 (rank : 1804)	NC score	-0.028613 (rank : 3101)
Query Neighborhood Hits	2923	Target Neighborhood Hits	805	Shared Neighborhood Hits	89
SwissProt Accessions	P57071, Q8N0X3, Q8NEX0, Q9NQV3	Gene names	PRDM15, C21orf83, ZNF298
Domain Architecture
Description	PR domain zinc finger protein 15 (PR domain-containing protein 15) (Zinc finger protein 298).

PWWP2_HUMAN
θ value	1.06291 (rank : 1805)	NC score	0.017444 (rank : 2251)
Query Neighborhood Hits	2923	Target Neighborhood Hits	80	Shared Neighborhood Hits	33
SwissProt Accessions	Q6NUJ5, Q5SZI0, Q6ZQX5, Q96F43	Gene names	PWWP2
Domain Architecture	No domain graphic available
Description	PWWP domain-containing protein 2.

RBBP6_HUMAN
θ value	1.06291 (rank : 1806)	NC score	0.053415 (rank : 1629)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1135	Shared Neighborhood Hits	448
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RBM28_HUMAN
θ value	1.06291 (rank : 1807)	NC score	-0.003850 (rank : 2956)
Query Neighborhood Hits	2923	Target Neighborhood Hits	307	Shared Neighborhood Hits	55
SwissProt Accessions	Q9NW13, Q96CV3	Gene names	RBM28
Domain Architecture	No domain graphic available
Description	RNA-binding protein 28 (RNA-binding motif protein 28).

REN3A_HUMAN
θ value	1.06291 (rank : 1808)	NC score	0.031797 (rank : 1987)
Query Neighborhood Hits	2923	Target Neighborhood Hits	248	Shared Neighborhood Hits	128
SwissProt Accessions	Q9H1J1, Q5T8C3, Q5T8C9, Q7Z6N3, Q86YK1, Q9BZI8	Gene names	UPF3A, RENT3A, UPF3
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3A (Nonsense mRNA reducing factor 3A) (Up-frameshift suppressor 3 homolog A) (hUpf3).

RN5A_MOUSE
θ value	1.06291 (rank : 1809)	NC score	0.258106 (rank : 1027)
Query Neighborhood Hits	2923	Target Neighborhood Hits	899	Shared Neighborhood Hits	611
SwissProt Accessions	Q05921, Q9ERU7	Gene names	Rnasel, Rns4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

SAPS1_MOUSE
θ value	1.06291 (rank : 1810)	NC score	0.009460 (rank : 2493)
Query Neighborhood Hits	2923	Target Neighborhood Hits	144	Shared Neighborhood Hits	65
SwissProt Accessions	Q7TSI3, Q80TJ4	Gene names	Saps1, Kiaa1115
Domain Architecture	No domain graphic available
Description	SAPS domain family member 1.

SCML2_HUMAN
θ value	1.06291 (rank : 1811)	NC score	0.003242 (rank : 2718)
Query Neighborhood Hits	2923	Target Neighborhood Hits	68	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UQR0, Q86U98, Q8IWD0, Q8NDP2, Q9UGC5	Gene names	SCML2
Domain Architecture
Description	Sex comb on midleg-like protein 2.

SIGIR_HUMAN
θ value	1.06291 (rank : 1812)	NC score	0.050781 (rank : 1684)
Query Neighborhood Hits	2923	Target Neighborhood Hits	53	Shared Neighborhood Hits	31
SwissProt Accessions	Q6IA17, Q3KQY2, Q6UXI3, Q9H733	Gene names	SIGIRR
Domain Architecture	No domain graphic available
Description	Single Ig IL-1-related receptor (Single Ig IL-1R-related molecule) (Single immunoglobulin domain-containing IL1R-related protein) (Toll/interleukin-1 receptor 8) (TIR8).

SKIL_HUMAN
θ value	1.06291 (rank : 1813)	NC score	0.035730 (rank : 1912)
Query Neighborhood Hits	2923	Target Neighborhood Hits	460	Shared Neighborhood Hits	223
SwissProt Accessions	P12757, O00464, P12756, Q07501	Gene names	SKIL, SNO
Domain Architecture
Description	Ski-like protein (Ski-related protein) (Ski-related oncogene).

SYAP1_MOUSE
θ value	1.06291 (rank : 1814)	NC score	0.015389 (rank : 2308)
Query Neighborhood Hits	2923	Target Neighborhood Hits	55	Shared Neighborhood Hits	32
SwissProt Accessions	Q9D5V6, Q3UI67, Q9D870	Gene names	Syap1
Domain Architecture
Description	Synapse-associated protein 1.

TP53B_HUMAN
θ value	1.06291 (rank : 1815)	NC score	0.039017 (rank : 1855)
Query Neighborhood Hits	2923	Target Neighborhood Hits	413	Shared Neighborhood Hits	181
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

VRK3_MOUSE
θ value	1.06291 (rank : 1816)	NC score	0.206706 (rank : 1070)
Query Neighborhood Hits	2923	Target Neighborhood Hits	342	Shared Neighborhood Hits	320
SwissProt Accessions	Q8K3G5, Q921W6	Gene names	Vrk3
Domain Architecture
Description	Serine/threonine-protein kinase VRK3 (EC 2.7.11.1) (Vaccinia-related kinase 3).

WDR46_HUMAN
θ value	1.06291 (rank : 1817)	NC score	0.004705 (rank : 2651)
Query Neighborhood Hits	2923	Target Neighborhood Hits	147	Shared Neighborhood Hits	24
SwissProt Accessions	O15213, Q5STK5	Gene names	WDR46, BING4, C6orf11
Domain Architecture
Description	WD repeat protein 46 (WD repeat protein BING4).

ZCPW1_MOUSE
θ value	1.06291 (rank : 1818)	NC score	0.032413 (rank : 1979)
Query Neighborhood Hits	2923	Target Neighborhood Hits	307	Shared Neighborhood Hits	155
SwissProt Accessions	Q6IR42	Gene names	Zcwpw1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1 homolog.

AMGO1_MOUSE
θ value	1.38821 (rank : 1819)	NC score	0.052883 (rank : 1640)
Query Neighborhood Hits	2923	Target Neighborhood Hits	325	Shared Neighborhood Hits	115
SwissProt Accessions	Q80ZD8, Q69ZQ0, Q8R5D4, Q921U9	Gene names	Amigo1, Ali2, Amigo, Kiaa1163
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 1 precursor (AMIGO-1) (Alivin-2).

AMPH_MOUSE
θ value	1.38821 (rank : 1820)	NC score	0.037654 (rank : 1880)
Query Neighborhood Hits	2923	Target Neighborhood Hits	291	Shared Neighborhood Hits	129
SwissProt Accessions	Q7TQF7, Q8R1C4	Gene names	Amph, Amph1
Domain Architecture
Description	Amphiphysin.

APBA1_HUMAN
θ value	1.38821 (rank : 1821)	NC score	0.011000 (rank : 2445)
Query Neighborhood Hits	2923	Target Neighborhood Hits	325	Shared Neighborhood Hits	79
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

BASP_MOUSE
θ value	1.38821 (rank : 1822)	NC score	0.084839 (rank : 1248)
Query Neighborhood Hits	2923	Target Neighborhood Hits	260	Shared Neighborhood Hits	145
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

CA049_MOUSE
θ value	1.38821 (rank : 1823)	NC score	0.025949 (rank : 2089)
Query Neighborhood Hits	2923	Target Neighborhood Hits	121	Shared Neighborhood Hits	82
SwissProt Accessions	Q14BK3, Q4KKY9, Q9D9J9	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf49 homolog.

CALX_MOUSE
θ value	1.38821 (rank : 1824)	NC score	0.008569 (rank : 2521)
Query Neighborhood Hits	2923	Target Neighborhood Hits	76	Shared Neighborhood Hits	28
SwissProt Accessions	P35564	Gene names	Canx
Domain Architecture
Description	Calnexin precursor.

CBS_HUMAN
θ value	1.38821 (rank : 1825)	NC score	0.009499 (rank : 2489)
Query Neighborhood Hits	2923	Target Neighborhood Hits	21	Shared Neighborhood Hits	6
SwissProt Accessions	P35520, Q99425, Q9BWC5	Gene names	CBS
Domain Architecture
Description	Cystathionine beta-synthase (EC 4.2.1.22) (Serine sulfhydrase) (Beta- thionase).

CC025_HUMAN
θ value	1.38821 (rank : 1826)	NC score	0.011490 (rank : 2426)
Query Neighborhood Hits	2923	Target Neighborhood Hits	31	Shared Neighborhood Hits	16
SwissProt Accessions	Q6NXP0, Q69YX4	Gene names	C3orf25
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf25.

CCD60_MOUSE
θ value	1.38821 (rank : 1827)	NC score	0.010118 (rank : 2466)
Query Neighborhood Hits	2923	Target Neighborhood Hits	18	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C4J0, Q6DIA4, Q6PAQ3	Gene names	Ccdc60
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 60.

CCD96_MOUSE
θ value	1.38821 (rank : 1828)	NC score	0.068078 (rank : 1322)
Query Neighborhood Hits	2923	Target Neighborhood Hits	704	Shared Neighborhood Hits	363
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CD7_HUMAN
θ value	1.38821 (rank : 1829)	NC score	0.047075 (rank : 1741)
Query Neighborhood Hits	2923	Target Neighborhood Hits	190	Shared Neighborhood Hits	90
SwissProt Accessions	P09564	Gene names	CD7
Domain Architecture
Description	T-cell antigen CD7 precursor (GP40) (T-cell leukemia antigen) (TP41) (Leu-9).

CK5P2_HUMAN
θ value	1.38821 (rank : 1830)	NC score	0.059488 (rank : 1457)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1433	Shared Neighborhood Hits	517
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

CO9A3_HUMAN
θ value	1.38821 (rank : 1831)	NC score	0.013310 (rank : 2376)
Query Neighborhood Hits	2923	Target Neighborhood Hits	361	Shared Neighborhood Hits	92
SwissProt Accessions	Q14050, Q13681, Q9H4G9, Q9UPE2	Gene names	COL9A3
Domain Architecture	No domain graphic available
Description	Collagen alpha-3(IX) chain precursor.

CU013_HUMAN
θ value	1.38821 (rank : 1832)	NC score	0.043971 (rank : 1779)
Query Neighborhood Hits	2923	Target Neighborhood Hits	405	Shared Neighborhood Hits	207
SwissProt Accessions	O95447	Gene names	C21orf13
Domain Architecture
Description	Protein C21orf13.

CYH3_HUMAN
θ value	1.38821 (rank : 1833)	NC score	0.007191 (rank : 2563)
Query Neighborhood Hits	2923	Target Neighborhood Hits	137	Shared Neighborhood Hits	41
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

CYH3_MOUSE
θ value	1.38821 (rank : 1834)	NC score	0.010215 (rank : 2463)
Query Neighborhood Hits	2923	Target Neighborhood Hits	148	Shared Neighborhood Hits	44
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

DAB2P_HUMAN
θ value	1.38821 (rank : 1835)	NC score	0.016809 (rank : 2269)
Query Neighborhood Hits	2923	Target Neighborhood Hits	303	Shared Neighborhood Hits	145
SwissProt Accessions	Q5VWQ8, Q8TDL2, Q96SE1, Q9C0C0	Gene names	DAB2IP, AF9Q34, AIP1, KIAA1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein) (DAB2 interaction protein) (ASK-interacting protein 1).

DAB2P_MOUSE
θ value	1.38821 (rank : 1836)	NC score	0.016101 (rank : 2289)
Query Neighborhood Hits	2923	Target Neighborhood Hits	284	Shared Neighborhood Hits	138
SwissProt Accessions	Q3UHC7, Q3TPD5, Q3UH44, Q6JTV1, Q80T97	Gene names	Dab2ip, Kiaa1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein).

DCP1A_HUMAN
θ value	1.38821 (rank : 1837)	NC score	0.027801 (rank : 2052)
Query Neighborhood Hits	2923	Target Neighborhood Hits	228	Shared Neighborhood Hits	107
SwissProt Accessions	Q9NPI6	Gene names	DCP1A, SMIF
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (Smad4-interacting transcriptional co-activator).

DOCK2_MOUSE
θ value	1.38821 (rank : 1838)	NC score	0.003867 (rank : 2684)
Query Neighborhood Hits	2923	Target Neighborhood Hits	104	Shared Neighborhood Hits	32
SwissProt Accessions	Q8C3J5, Q99M79	Gene names	Dock2
Domain Architecture
Description	Dedicator of cytokinesis protein 2 (Hch protein).

DREB_HUMAN
θ value	1.38821 (rank : 1839)	NC score	0.054190 (rank : 1605)
Query Neighborhood Hits	2923	Target Neighborhood Hits	450	Shared Neighborhood Hits	254
SwissProt Accessions	Q16643	Gene names	DBN1
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

E41L2_HUMAN
θ value	1.38821 (rank : 1840)	NC score	0.015234 (rank : 2314)
Query Neighborhood Hits	2923	Target Neighborhood Hits	287	Shared Neighborhood Hits	150
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

E41L2_MOUSE
θ value	1.38821 (rank : 1841)	NC score	0.019002 (rank : 2222)
Query Neighborhood Hits	2923	Target Neighborhood Hits	459	Shared Neighborhood Hits	213
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

ENKUR_HUMAN
θ value	1.38821 (rank : 1842)	NC score	0.012975 (rank : 2386)
Query Neighborhood Hits	2923	Target Neighborhood Hits	64	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TC29	Gene names	C10orf63
Domain Architecture	No domain graphic available
Description	Enkurin.

ERC2_HUMAN
θ value	1.38821 (rank : 1843)	NC score	0.052180 (rank : 1660)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1156	Shared Neighborhood Hits	410
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

ESPL1_HUMAN
θ value	1.38821 (rank : 1844)	NC score	0.006258 (rank : 2595)
Query Neighborhood Hits	2923	Target Neighborhood Hits	95	Shared Neighborhood Hits	35
SwissProt Accessions	Q14674	Gene names	ESPL1, ESP1, KIAA0165
Domain Architecture
Description	Separin (EC 3.4.22.49) (Separase) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein).

GOPC_MOUSE
θ value	1.38821 (rank : 1845)	NC score	0.010116 (rank : 2467)
Query Neighborhood Hits	2923	Target Neighborhood Hits	323	Shared Neighborhood Hits	119
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

GP158_HUMAN
θ value	1.38821 (rank : 1846)	NC score	0.023342 (rank : 2140)
Query Neighborhood Hits	2923	Target Neighborhood Hits	221	Shared Neighborhood Hits	92
SwissProt Accessions	Q5T848, Q6QR81, Q9ULT3	Gene names	GPR158, KIAA1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

GT2D1_HUMAN
θ value	1.38821 (rank : 1847)	NC score	0.010586 (rank : 2453)
Query Neighborhood Hits	2923	Target Neighborhood Hits	46	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UHL9, O95444, Q75MX7, Q86UM3, Q8WVC4, Q9UHK8, Q9UI91	Gene names	GTF2IRD1, CREAM1, GTF3, MUSTRD1, RBAP2, WBSCR11, WBSCR12
Domain Architecture
Description	General transcription factor II-I repeat domain-containing protein 1 (GTF2I repeat domain-containing protein 1) (Muscle TFII-I repeat domain-containing protein 1) (General transcription factor III) (Slow- muscle-fiber enhancer-binding protein) (USE B1-binding protein) (MusTRD1/BEN) (Williams-Beuren syndrome chromosome region 11 protein).

H15_MOUSE
θ value	1.38821 (rank : 1848)	NC score	0.020079 (rank : 2203)
Query Neighborhood Hits	2923	Target Neighborhood Hits	79	Shared Neighborhood Hits	44
SwissProt Accessions	P43276, Q9CRM8	Gene names	Hist1h1b, H1f5
Domain Architecture
Description	Histone H1.5 (H1 VAR.5) (H1b).

HCLS1_MOUSE
θ value	1.38821 (rank : 1849)	NC score	0.023053 (rank : 2145)
Query Neighborhood Hits	2923	Target Neighborhood Hits	329	Shared Neighborhood Hits	131
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

HM20A_MOUSE
θ value	1.38821 (rank : 1850)	NC score	0.015890 (rank : 2291)
Query Neighborhood Hits	2923	Target Neighborhood Hits	348	Shared Neighborhood Hits	154
SwissProt Accessions	Q9DC33, Q3LSF9, Q6NV87, Q8BSK1, Q8C3C1, Q8CAA0, Q9CYG2	Gene names	Hmg20a, Ibraf
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (iBRAF) (Inhibitor of BRAF35) (HMG domain protein HMGX1).

HMMR_HUMAN
θ value	1.38821 (rank : 1851)	NC score	0.059146 (rank : 1466)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1082	Shared Neighborhood Hits	401
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

IL16_HUMAN
θ value	1.38821 (rank : 1852)	NC score	0.003474 (rank : 2709)
Query Neighborhood Hits	2923	Target Neighborhood Hits	207	Shared Neighborhood Hits	54
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

IZUM1_MOUSE
θ value	1.38821 (rank : 1853)	NC score	0.018694 (rank : 2223)
Query Neighborhood Hits	2923	Target Neighborhood Hits	41	Shared Neighborhood Hits	18
SwissProt Accessions	Q9D9J7	Gene names	Izumo1
Domain Architecture	No domain graphic available
Description	Izumo sperm-egg fusion protein 1 precursor (Sperm-specific protein izumo).

JHD2A_HUMAN
θ value	1.38821 (rank : 1854)	NC score	0.006794 (rank : 2579)
Query Neighborhood Hits	2923	Target Neighborhood Hits	118	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y4C1, Q53S72, Q68D47, Q68UT9, Q6N050, Q8IY08	Gene names	JMJD1A, JHDM2A, JMJD1, KIAA0742
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2A (EC 1.14.11.-) (Jumonji domain-containing protein 1A).

JHD3C_HUMAN
θ value	1.38821 (rank : 1855)	NC score	0.003805 (rank : 2688)
Query Neighborhood Hits	2923	Target Neighborhood Hits	91	Shared Neighborhood Hits	33
SwissProt Accessions	Q9H3R0, O94877, Q2M3M0, Q5JUC9, Q5VYJ2, Q5VYJ3	Gene names	JMJD2C, GASC1, JHDM3C, KIAA0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C) (Gene amplified in squamous cell carcinoma 1 protein) (GASC-1 protein).

K1914_HUMAN
θ value	1.38821 (rank : 1856)	NC score	0.024322 (rank : 2122)
Query Neighborhood Hits	2923	Target Neighborhood Hits	255	Shared Neighborhood Hits	124
SwissProt Accessions	Q8N4X5, Q8TB54, Q96PX4, Q96SY5	Gene names	KIAA1914
Domain Architecture	No domain graphic available
Description	Protein KIAA1914.

KIF14_HUMAN
θ value	1.38821 (rank : 1857)	NC score	0.027808 (rank : 2051)
Query Neighborhood Hits	2923	Target Neighborhood Hits	732	Shared Neighborhood Hits	345
SwissProt Accessions	Q15058	Gene names	KIF14, KIAA0042
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF14.

KIF3B_MOUSE
θ value	1.38821 (rank : 1858)	NC score	0.020697 (rank : 2187)
Query Neighborhood Hits	2923	Target Neighborhood Hits	533	Shared Neighborhood Hits	249
SwissProt Accessions	Q61771	Gene names	Kif3b
Domain Architecture
Description	Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B).

KIF4A_HUMAN
θ value	1.38821 (rank : 1859)	NC score	0.044221 (rank : 1775)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1159	Shared Neighborhood Hits	440
SwissProt Accessions	O95239, Q86TN3, Q86XX7, Q9NNY6, Q9NY24, Q9UMW3	Gene names	KIF4A, KIF4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

KV1L_HUMAN
θ value	1.38821 (rank : 1860)	NC score	-0.003106 (rank : 2937)
Query Neighborhood Hits	2923	Target Neighborhood Hits	239	Shared Neighborhood Hits	68
SwissProt Accessions	P01604	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-I region Kue.

LRC45_MOUSE
θ value	1.38821 (rank : 1861)	NC score	0.063154 (rank : 1371)
Query Neighborhood Hits	2923	Target Neighborhood Hits	959	Shared Neighborhood Hits	386
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

LV4C_HUMAN
θ value	1.38821 (rank : 1862)	NC score	0.010141 (rank : 2465)
Query Neighborhood Hits	2923	Target Neighborhood Hits	284	Shared Neighborhood Hits	97
SwissProt Accessions	P01717	Gene names
Domain Architecture	No domain graphic available
Description	Ig lambda chain V-IV region Hil.

MACF1_MOUSE
θ value	1.38821 (rank : 1863)	NC score	0.038990 (rank : 1856)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1313	Shared Neighborhood Hits	419
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

MCCA_HUMAN
θ value	1.38821 (rank : 1864)	NC score	0.000789 (rank : 2813)
Query Neighborhood Hits	2923	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	Q96RQ3, Q59ES4, Q9H959, Q9NS97	Gene names	MCCC1, MCCA
Domain Architecture
Description	Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial precursor (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 1) (MCCase subunit alpha) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha) (3- methylcrotonyl-CoA carboxylase biotin-containing subunit).

MYCL2_HUMAN
θ value	1.38821 (rank : 1865)	NC score	0.002373 (rank : 2750)
Query Neighborhood Hits	2923	Target Neighborhood Hits	63	Shared Neighborhood Hits	11
SwissProt Accessions	P12525	Gene names	MYCL2
Domain Architecture
Description	L-myc-2 protein.

MYO6_HUMAN
θ value	1.38821 (rank : 1866)	NC score	0.044110 (rank : 1777)
Query Neighborhood Hits	2923	Target Neighborhood Hits	727	Shared Neighborhood Hits	341
SwissProt Accessions	Q9UM54, Q9BZZ7, Q9UEG2	Gene names	MYO6, KIAA0389
Domain Architecture
Description	Myosin-6 (Myosin VI).

MYSM1_HUMAN
θ value	1.38821 (rank : 1867)	NC score	0.007003 (rank : 2571)
Query Neighborhood Hits	2923	Target Neighborhood Hits	73	Shared Neighborhood Hits	30
SwissProt Accessions	Q5VVJ2, Q7Z3G8, Q96PX3	Gene names	MYSM1, KIAA1915
Domain Architecture	No domain graphic available
Description	Protein MYSM1 (Myb-like, SWIRM and MPN domain-containing protein 1).

NHS_HUMAN
θ value	1.38821 (rank : 1868)	NC score	0.029402 (rank : 2016)
Query Neighborhood Hits	2923	Target Neighborhood Hits	198	Shared Neighborhood Hits	92
SwissProt Accessions	Q6T4R5, Q5J7Q0, Q5J7Q1, Q68DR5	Gene names	NHS
Domain Architecture	No domain graphic available
Description	Nance-Horan syndrome protein (Congenital cataracts and dental anomalies protein).

NUP62_HUMAN
θ value	1.38821 (rank : 1869)	NC score	0.032930 (rank : 1970)
Query Neighborhood Hits	2923	Target Neighborhood Hits	195	Shared Neighborhood Hits	116
SwissProt Accessions	P37198, Q503A4, Q96C43, Q9NSL1	Gene names	NUP62
Domain Architecture
Description	Nuclear pore glycoprotein p62 (62 kDa nucleoporin).

PHF14_MOUSE
θ value	1.38821 (rank : 1870)	NC score	0.018293 (rank : 2230)
Query Neighborhood Hits	2923	Target Neighborhood Hits	342	Shared Neighborhood Hits	167
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

PHF3_HUMAN
θ value	1.38821 (rank : 1871)	NC score	0.022342 (rank : 2160)
Query Neighborhood Hits	2923	Target Neighborhood Hits	419	Shared Neighborhood Hits	164
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

PHLB2_HUMAN
θ value	1.38821 (rank : 1872)	NC score	0.055320 (rank : 1571)
Query Neighborhood Hits	2923	Target Neighborhood Hits	964	Shared Neighborhood Hits	402
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

PI3R4_HUMAN
θ value	1.38821 (rank : 1873)	NC score	0.295788 (rank : 1006)
Query Neighborhood Hits	2923	Target Neighborhood Hits	534	Shared Neighborhood Hits	350
SwissProt Accessions	Q99570	Gene names	PIK3R4
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 4 (EC 2.7.11.1) (PI3- kinase regulatory subunit 4) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein).

PSIP1_MOUSE
θ value	1.38821 (rank : 1874)	NC score	0.024925 (rank : 2108)
Query Neighborhood Hits	2923	Target Neighborhood Hits	313	Shared Neighborhood Hits	147
SwissProt Accessions	Q99JF8, Q3TEJ7, Q3TTD7, Q3UTA1, Q80WQ7, Q99JF7, Q99LR4, Q9CT03	Gene names	Psip1, Ledgf
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (mLEDGF).

RAD50_HUMAN
θ value	1.38821 (rank : 1875)	NC score	0.059795 (rank : 1449)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1317	Shared Neighborhood Hits	453
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

RBP1_HUMAN
θ value	1.38821 (rank : 1876)	NC score	0.026015 (rank : 2087)
Query Neighborhood Hits	2923	Target Neighborhood Hits	521	Shared Neighborhood Hits	230
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

RBP1_MOUSE
θ value	1.38821 (rank : 1877)	NC score	0.024624 (rank : 2115)
Query Neighborhood Hits	2923	Target Neighborhood Hits	493	Shared Neighborhood Hits	229
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

RFIP1_HUMAN
θ value	1.38821 (rank : 1878)	NC score	0.029888 (rank : 2005)
Query Neighborhood Hits	2923	Target Neighborhood Hits	236	Shared Neighborhood Hits	113
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

RMP_HUMAN
θ value	1.38821 (rank : 1879)	NC score	0.013938 (rank : 2362)
Query Neighborhood Hits	2923	Target Neighborhood Hits	40	Shared Neighborhood Hits	17
SwissProt Accessions	O94763	Gene names	RMP, C19orf2
Domain Architecture
Description	RNA polymerase II subunit 5-mediating protein (RPB5-mediating protein).

SCEL_HUMAN
θ value	1.38821 (rank : 1880)	NC score	0.009412 (rank : 2495)
Query Neighborhood Hits	2923	Target Neighborhood Hits	117	Shared Neighborhood Hits	43
SwissProt Accessions	O95171	Gene names	SCEL
Domain Architecture
Description	Sciellin.

SEM3E_HUMAN
θ value	1.38821 (rank : 1881)	NC score	0.006904 (rank : 2575)
Query Neighborhood Hits	2923	Target Neighborhood Hits	73	Shared Neighborhood Hits	26
SwissProt Accessions	O15041, Q75M94, Q75M97	Gene names	SEMA3E, KIAA0331
Domain Architecture	No domain graphic available
Description	Semaphorin-3E precursor.

SEM3F_HUMAN
θ value	1.38821 (rank : 1882)	NC score	0.016952 (rank : 2264)
Query Neighborhood Hits	2923	Target Neighborhood Hits	100	Shared Neighborhood Hits	54
SwissProt Accessions	Q13275, Q13274, Q13372, Q15704	Gene names	SEMA3F
Domain Architecture
Description	Semaphorin-3F precursor (Semaphorin IV) (Sema IV) (Sema III/F).

SEZ6L_HUMAN
θ value	1.38821 (rank : 1883)	NC score	0.005131 (rank : 2627)
Query Neighborhood Hits	2923	Target Neighborhood Hits	289	Shared Neighborhood Hits	75
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

SF3A1_HUMAN
θ value	1.38821 (rank : 1884)	NC score	0.033167 (rank : 1965)
Query Neighborhood Hits	2923	Target Neighborhood Hits	199	Shared Neighborhood Hits	104
SwissProt Accessions	Q15459	Gene names	SF3A1, SAP114
Domain Architecture
Description	Splicing factor 3 subunit 1 (Spliceosome-associated protein 114) (SAP 114) (SF3a120).

SH2D3_HUMAN
θ value	1.38821 (rank : 1885)	NC score	0.025148 (rank : 2105)
Query Neighborhood Hits	2923	Target Neighborhood Hits	188	Shared Neighborhood Hits	62
SwissProt Accessions	Q8N5H7, Q5HYE5, Q6UY42, Q8N6X3, Q9Y2X5	Gene names	SH2D3C, NSP3
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (Novel SH2-containing protein 3).

SLAF5_HUMAN
θ value	1.38821 (rank : 1886)	NC score	0.058821 (rank : 1474)
Query Neighborhood Hits	2923	Target Neighborhood Hits	65	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UIB8, O15430, O95266, O95660, Q5H9R1, Q6FHA8, Q8WLP1, Q8WWI8, Q9UF04, Q9UIB6, Q9UIB7, Q9UIT7	Gene names	CD84, SLAMF5
Domain Architecture	No domain graphic available
Description	SLAM family member 5 precursor (Signaling lymphocytic activation molecule 5) (Leukocyte differentiation antigen CD84) (CD84 antigen) (Cell surface antigen MAX.3) (Hly9-beta).

SLIT2_MOUSE
θ value	1.38821 (rank : 1887)	NC score	0.042960 (rank : 1797)
Query Neighborhood Hits	2923	Target Neighborhood Hits	684	Shared Neighborhood Hits	123
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SMCA4_HUMAN
θ value	1.38821 (rank : 1888)	NC score	0.027401 (rank : 2056)
Query Neighborhood Hits	2923	Target Neighborhood Hits	597	Shared Neighborhood Hits	284
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

SPR1B_HUMAN
θ value	1.38821 (rank : 1889)	NC score	0.033579 (rank : 1958)
Query Neighborhood Hits	2923	Target Neighborhood Hits	102	Shared Neighborhood Hits	38
SwissProt Accessions	P22528, P22529, P22530, Q5T524	Gene names	SPRR1B
Domain Architecture	No domain graphic available
Description	Cornifin B (Small proline-rich protein IB) (SPR-IB) (14.9 kDa pancornulin).

SPT6H_MOUSE
θ value	1.38821 (rank : 1890)	NC score	0.011006 (rank : 2442)
Query Neighborhood Hits	2923	Target Neighborhood Hits	104	Shared Neighborhood Hits	43
SwissProt Accessions	Q62383, Q5SYM0, Q6GQS3, Q6ZQI0, Q8BQY6	Gene names	Supt6h, Kiaa0162
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT6.

SRRM2_HUMAN
θ value	1.38821 (rank : 1891)	NC score	0.094786 (rank : 1220)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1296	Shared Neighborhood Hits	509
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

STAT6_HUMAN
θ value	1.38821 (rank : 1892)	NC score	0.005098 (rank : 2633)
Query Neighborhood Hits	2923	Target Neighborhood Hits	132	Shared Neighborhood Hits	50
SwissProt Accessions	P42226	Gene names	STAT6
Domain Architecture
Description	Signal transducer and activator of transcription 6 (IL-4 Stat).

SYTL2_MOUSE
θ value	1.38821 (rank : 1893)	NC score	0.018649 (rank : 2225)
Query Neighborhood Hits	2923	Target Neighborhood Hits	253	Shared Neighborhood Hits	72
SwissProt Accessions	Q99N50, Q8BT37, Q99J89, Q99J90, Q99N51, Q99N52, Q99N55, Q99N56	Gene names	Sytl2, Slp2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

TAF3_HUMAN
θ value	1.38821 (rank : 1894)	NC score	0.058723 (rank : 1476)
Query Neighborhood Hits	2923	Target Neighborhood Hits	568	Shared Neighborhood Hits	289
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TAU_HUMAN
θ value	1.38821 (rank : 1895)	NC score	0.061079 (rank : 1412)
Query Neighborhood Hits	2923	Target Neighborhood Hits	448	Shared Neighborhood Hits	195
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

WDR46_MOUSE
θ value	1.38821 (rank : 1896)	NC score	0.014121 (rank : 2354)
Query Neighborhood Hits	2923	Target Neighborhood Hits	243	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Z0H1	Gene names	Wdr46, Bing4
Domain Architecture
Description	WD repeat protein 46 (WD repeat protein BING4).

WDTC1_MOUSE
θ value	1.38821 (rank : 1897)	NC score	-0.009593 (rank : 3053)
Query Neighborhood Hits	2923	Target Neighborhood Hits	298	Shared Neighborhood Hits	21
SwissProt Accessions	Q80ZK9	Gene names	Wdtc1
Domain Architecture
Description	WD and tetratricopeptide repeats protein 1.

ZN206_HUMAN
θ value	1.38821 (rank : 1898)	NC score	-0.028879 (rank : 3104)
Query Neighborhood Hits	2923	Target Neighborhood Hits	853	Shared Neighborhood Hits	109
SwissProt Accessions	Q96SZ4	Gene names	ZNF206, ZSCAN10
Domain Architecture	No domain graphic available
Description	Zinc finger protein 206 (Zinc finger and SCAN domain-containing protein 10).

ZN438_HUMAN
θ value	1.38821 (rank : 1899)	NC score	-0.022199 (rank : 3083)
Query Neighborhood Hits	2923	Target Neighborhood Hits	906	Shared Neighborhood Hits	140
SwissProt Accessions	Q7Z4V0, Q5T426, Q658Q4, Q6ZN65	Gene names	ZNF438
Domain Architecture	No domain graphic available
Description	Zinc finger protein 438.

ACTN2_HUMAN
θ value	1.81305 (rank : 1900)	NC score	0.002167 (rank : 2758)
Query Neighborhood Hits	2923	Target Neighborhood Hits	295	Shared Neighborhood Hits	114
SwissProt Accessions	P35609, Q86TF4, Q86TI8	Gene names	ACTN2
Domain Architecture
Description	Alpha-actinin-2 (Alpha actinin skeletal muscle isoform 2) (F-actin cross-linking protein).

ACTN2_MOUSE
θ value	1.81305 (rank : 1901)	NC score	0.001241 (rank : 2793)
Query Neighborhood Hits	2923	Target Neighborhood Hits	287	Shared Neighborhood Hits	111
SwissProt Accessions	Q9JI91	Gene names	Actn2
Domain Architecture
Description	Alpha-actinin-2 (Alpha actinin skeletal muscle isoform 2) (F-actin cross-linking protein).

ADA12_MOUSE
θ value	1.81305 (rank : 1902)	NC score	0.003068 (rank : 2724)
Query Neighborhood Hits	2923	Target Neighborhood Hits	474	Shared Neighborhood Hits	141
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

AF9_HUMAN
θ value	1.81305 (rank : 1903)	NC score	0.033287 (rank : 1962)
Query Neighborhood Hits	2923	Target Neighborhood Hits	202	Shared Neighborhood Hits	88
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

AFAD_HUMAN
θ value	1.81305 (rank : 1904)	NC score	0.035314 (rank : 1926)
Query Neighborhood Hits	2923	Target Neighborhood Hits	689	Shared Neighborhood Hits	287
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

AMGO2_HUMAN
θ value	1.81305 (rank : 1905)	NC score	0.080078 (rank : 1264)
Query Neighborhood Hits	2923	Target Neighborhood Hits	357	Shared Neighborhood Hits	153
SwissProt Accessions	Q86SJ2, Q7Z4A0, Q96CN8	Gene names	AMIGO2, ALI1
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 2 precursor (AMIGO-2) (Alivin-1) (Differentially expressed in gastric adenocarcinomas) (DEGA).

ANLN_MOUSE
θ value	1.81305 (rank : 1906)	NC score	0.031832 (rank : 1984)
Query Neighborhood Hits	2923	Target Neighborhood Hits	297	Shared Neighborhood Hits	167
SwissProt Accessions	Q8K298, Q8BL79, Q8BLB3, Q8K2N0, Q9CUY0	Gene names	Anln
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

ANR12_HUMAN
θ value	1.81305 (rank : 1907)	NC score	0.038302 (rank : 1869)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1081	Shared Neighborhood Hits	410
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

ANR25_MOUSE
θ value	1.81305 (rank : 1908)	NC score	0.014600 (rank : 2338)
Query Neighborhood Hits	2923	Target Neighborhood Hits	398	Shared Neighborhood Hits	102
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

ANXA7_HUMAN
θ value	1.81305 (rank : 1909)	NC score	-0.000896 (rank : 2876)
Query Neighborhood Hits	2923	Target Neighborhood Hits	168	Shared Neighborhood Hits	50
SwissProt Accessions	P20073	Gene names	ANXA7, ANX7, SNX
Domain Architecture
Description	Annexin A7 (Annexin VII) (Synexin).

ARHG1_MOUSE
θ value	1.81305 (rank : 1910)	NC score	0.008684 (rank : 2515)
Query Neighborhood Hits	2923	Target Neighborhood Hits	266	Shared Neighborhood Hits	94
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

ARID2_HUMAN
θ value	1.81305 (rank : 1911)	NC score	0.017677 (rank : 2247)
Query Neighborhood Hits	2923	Target Neighborhood Hits	302	Shared Neighborhood Hits	102
SwissProt Accessions	Q68CP9, Q5EB51, Q645I3, Q6ZRY5, Q7Z3I5, Q86T28, Q96SJ6, Q9HCL5	Gene names	ARID2, KIAA1557
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 2 (ARID domain- containing protein 2) (BRG1-associated factor 200) (BAF200).

ARMX4_HUMAN
θ value	1.81305 (rank : 1912)	NC score	0.015725 (rank : 2293)
Query Neighborhood Hits	2923	Target Neighborhood Hits	60	Shared Neighborhood Hits	31
SwissProt Accessions	Q5H9R4, Q5H9K8, Q8N8D6	Gene names	ARMCX4
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 4.

ATBF1_MOUSE
θ value	1.81305 (rank : 1913)	NC score	-0.006138 (rank : 2997)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1841	Shared Neighborhood Hits	403
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

AVR2A_HUMAN
θ value	1.81305 (rank : 1914)	NC score	0.513554 (rank : 829)
Query Neighborhood Hits	2923	Target Neighborhood Hits	767	Shared Neighborhood Hits	713
SwissProt Accessions	P27037, Q53TH4, Q6NWV2, Q92474	Gene names	ACVR2A, ACVR2
Domain Architecture
Description	Activin receptor type 2A precursor (EC 2.7.11.30) (Activin receptor type IIA) (ACTR-IIA) (ACTRIIA).

AVR2A_MOUSE
θ value	1.81305 (rank : 1915)	NC score	0.513566 (rank : 828)
Query Neighborhood Hits	2923	Target Neighborhood Hits	767	Shared Neighborhood Hits	713
SwissProt Accessions	P27038	Gene names	Acvr2a, Acvr2
Domain Architecture
Description	Activin receptor type 2A precursor (EC 2.7.11.30) (Activin receptor type IIA) (ACTR-IIA).

CCD91_MOUSE
θ value	1.81305 (rank : 1916)	NC score	0.056877 (rank : 1536)
Query Neighborhood Hits	2923	Target Neighborhood Hits	699	Shared Neighborhood Hits	321
SwissProt Accessions	Q9D8L5, Q8R3N8, Q9D9E8	Gene names	Ccdc91, Ggabp
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner).

CCNL1_MOUSE
θ value	1.81305 (rank : 1917)	NC score	0.005817 (rank : 2606)
Query Neighborhood Hits	2923	Target Neighborhood Hits	71	Shared Neighborhood Hits	29
SwissProt Accessions	Q52KE7, Q8BQ75, Q8R5H9, Q922K0, Q9CSZ3, Q9WV44	Gene names	Ccnl1, Ania6a, Ccn1
Domain Architecture	No domain graphic available
Description	Cyclin-L1 (Cyclin-L) (Cyclin Ania-6a).

CF182_MOUSE
θ value	1.81305 (rank : 1918)	NC score	0.053260 (rank : 1632)
Query Neighborhood Hits	2923	Target Neighborhood Hits	551	Shared Neighborhood Hits	271
SwissProt Accessions	Q8VDS7, Q9CZE0, Q9D5A1	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf182 homolog.

CI039_HUMAN
θ value	1.81305 (rank : 1919)	NC score	0.065916 (rank : 1336)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1171	Shared Neighborhood Hits	448
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

CNTRB_MOUSE
θ value	1.81305 (rank : 1920)	NC score	0.067878 (rank : 1324)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1029	Shared Neighborhood Hits	426
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

CO5A3_HUMAN
θ value	1.81305 (rank : 1921)	NC score	0.011848 (rank : 2417)
Query Neighborhood Hits	2923	Target Neighborhood Hits	433	Shared Neighborhood Hits	112
SwissProt Accessions	P25940, Q9NZQ6	Gene names	COL5A3
Domain Architecture
Description	Collagen alpha-3(V) chain precursor.

CROCC_MOUSE
θ value	1.81305 (rank : 1922)	NC score	0.061533 (rank : 1400)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1460	Shared Neighborhood Hits	502
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

CSMD2_HUMAN
θ value	1.81305 (rank : 1923)	NC score	-0.007552 (rank : 3023)
Query Neighborhood Hits	2923	Target Neighborhood Hits	188	Shared Neighborhood Hits	25
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

CX039_HUMAN
θ value	1.81305 (rank : 1924)	NC score	0.008984 (rank : 2508)
Query Neighborhood Hits	2923	Target Neighborhood Hits	20	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PEV8, Q8WVP6, Q96AV3	Gene names	CXorf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein CXorf39.

CX039_MOUSE
θ value	1.81305 (rank : 1925)	NC score	0.009426 (rank : 2494)
Query Neighborhood Hits	2923	Target Neighborhood Hits	19	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K2D0, Q3U3R2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein CXorf39 homolog.

DMD_HUMAN
θ value	1.81305 (rank : 1926)	NC score	0.041522 (rank : 1820)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1135	Shared Neighborhood Hits	413
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

DMN_HUMAN
θ value	1.81305 (rank : 1927)	NC score	0.022883 (rank : 2149)
Query Neighborhood Hits	2923	Target Neighborhood Hits	690	Shared Neighborhood Hits	311
SwissProt Accessions	O15061	Gene names	DMN, KIAA0353
Domain Architecture
Description	Desmuslin.

DNL1_MOUSE
θ value	1.81305 (rank : 1928)	NC score	0.023322 (rank : 2141)
Query Neighborhood Hits	2923	Target Neighborhood Hits	110	Shared Neighborhood Hits	70
SwissProt Accessions	P37913	Gene names	Lig1, Lig-1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

DPPA4_MOUSE
θ value	1.81305 (rank : 1929)	NC score	0.006683 (rank : 2582)
Query Neighborhood Hits	2923	Target Neighborhood Hits	10	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CCG4, Q6P228, Q810Y6	Gene names	Dppa4
Domain Architecture	No domain graphic available
Description	Developmental pluripotency-associated protein 4.

E2AK1_HUMAN
θ value	1.81305 (rank : 1930)	NC score	0.663993 (rank : 517)
Query Neighborhood Hits	2923	Target Neighborhood Hits	833	Shared Neighborhood Hits	777
SwissProt Accessions	Q9BQI3, Q8NBW3, Q9HC02, Q9NYE0, Q9P0V6, Q9P1J5, Q9P2H8, Q9UHG4	Gene names	EIF2AK1, HRI, KIAA1369
Domain Architecture
Description	Eukaryotic translation initiation factor 2-alpha kinase 1 (EC 2.7.11.1) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Heme-controlled repressor) (HCR) (Hemin-sensitive initiation factor 2-alpha kinase).

ELOA1_HUMAN
θ value	1.81305 (rank : 1931)	NC score	0.028396 (rank : 2038)
Query Neighborhood Hits	2923	Target Neighborhood Hits	388	Shared Neighborhood Hits	150
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

EPOR_MOUSE
θ value	1.81305 (rank : 1932)	NC score	0.015008 (rank : 2318)
Query Neighborhood Hits	2923	Target Neighborhood Hits	52	Shared Neighborhood Hits	28
SwissProt Accessions	P14753, Q63852	Gene names	Epor
Domain Architecture
Description	Erythropoietin receptor precursor (EPO-R).

ESCO2_MOUSE
θ value	1.81305 (rank : 1933)	NC score	0.014201 (rank : 2349)
Query Neighborhood Hits	2923	Target Neighborhood Hits	29	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CIB9, Q3UMT6, Q6IQX5, Q8BNG9, Q8BQF8, Q9CRI8	Gene names	Esco2
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO2 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 2) (ECO1 homolog 2).

ETV5_MOUSE
θ value	1.81305 (rank : 1934)	NC score	0.001564 (rank : 2777)
Query Neighborhood Hits	2923	Target Neighborhood Hits	328	Shared Neighborhood Hits	99
SwissProt Accessions	Q9CXC9, Q3TG49, Q8C0F3, Q9JHB1	Gene names	Etv5
Domain Architecture	No domain graphic available
Description	ETS translocation variant 5.

FBN1_MOUSE
θ value	1.81305 (rank : 1935)	NC score	0.017068 (rank : 2260)
Query Neighborhood Hits	2923	Target Neighborhood Hits	563	Shared Neighborhood Hits	108
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

GAB1_HUMAN
θ value	1.81305 (rank : 1936)	NC score	0.014678 (rank : 2334)
Query Neighborhood Hits	2923	Target Neighborhood Hits	279	Shared Neighborhood Hits	106
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

GFPT2_HUMAN
θ value	1.81305 (rank : 1937)	NC score	0.003904 (rank : 2683)
Query Neighborhood Hits	2923	Target Neighborhood Hits	14	Shared Neighborhood Hits	5
SwissProt Accessions	O94808, Q53XM2, Q9BWS4	Gene names	GFPT2
Domain Architecture
Description	Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 2 (EC 2.6.1.16) (Hexosephosphate aminotransferase 2) (D-fructose-6- phosphate amidotransferase 2) (GFAT 2) (GFAT2).

HGS_HUMAN
θ value	1.81305 (rank : 1938)	NC score	0.014992 (rank : 2319)
Query Neighborhood Hits	2923	Target Neighborhood Hits	517	Shared Neighborhood Hits	194
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

HNF1A_MOUSE
θ value	1.81305 (rank : 1939)	NC score	0.009675 (rank : 2481)
Query Neighborhood Hits	2923	Target Neighborhood Hits	212	Shared Neighborhood Hits	69
SwissProt Accessions	P22361	Gene names	Tcf1, Hnf-1, Hnf-1a, Hnf1a
Domain Architecture
Description	Hepatocyte nuclear factor 1-alpha (HNF-1A) (Liver-specific transcription factor LF-B1) (LFB1).

HPLN1_HUMAN
θ value	1.81305 (rank : 1940)	NC score	0.021266 (rank : 2177)
Query Neighborhood Hits	2923	Target Neighborhood Hits	67	Shared Neighborhood Hits	54
SwissProt Accessions	P10915	Gene names	HAPLN1, CRTL1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 1 precursor (Proteoglycan link protein) (Cartilage link protein) (LP).

ICAL_HUMAN
θ value	1.81305 (rank : 1941)	NC score	0.037316 (rank : 1884)
Query Neighborhood Hits	2923	Target Neighborhood Hits	275	Shared Neighborhood Hits	140
SwissProt Accessions	P20810, O95360, Q96D08, Q9H1Z5	Gene names	CAST
Domain Architecture
Description	Calpastatin (Calpain inhibitor) (Sperm BS-17 component).

ICAM2_MOUSE
θ value	1.81305 (rank : 1942)	NC score	0.032873 (rank : 1971)
Query Neighborhood Hits	2923	Target Neighborhood Hits	17	Shared Neighborhood Hits	11
SwissProt Accessions	P35330, Q9D8Q4	Gene names	Icam2, Icam-2
Domain Architecture
Description	Intercellular adhesion molecule 2 precursor (ICAM-2) (CD102 antigen) (Lymphocyte function-associated AG-1 counter-receptor).

IFT81_MOUSE
θ value	1.81305 (rank : 1943)	NC score	0.062229 (rank : 1389)
Query Neighborhood Hits	2923	Target Neighborhood Hits	959	Shared Neighborhood Hits	392
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

INADL_MOUSE
θ value	1.81305 (rank : 1944)	NC score	0.005115 (rank : 2631)
Query Neighborhood Hits	2923	Target Neighborhood Hits	290	Shared Neighborhood Hits	72
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

INP5E_HUMAN
θ value	1.81305 (rank : 1945)	NC score	0.012342 (rank : 2406)
Query Neighborhood Hits	2923	Target Neighborhood Hits	201	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NRR6, Q15734	Gene names	INPP5E
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

JHD1B_MOUSE
θ value	1.81305 (rank : 1946)	NC score	0.003268 (rank : 2717)
Query Neighborhood Hits	2923	Target Neighborhood Hits	214	Shared Neighborhood Hits	77
SwissProt Accessions	Q6P1G2, Q3V396, Q6PFD0, Q6ZPE8, Q9CSF7, Q9QZN6	Gene names	Fbxl10, Fbl10, Jhdm1b, Kiaa3014
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10).

JPH2_HUMAN
θ value	1.81305 (rank : 1947)	NC score	0.026673 (rank : 2071)
Query Neighborhood Hits	2923	Target Neighborhood Hits	639	Shared Neighborhood Hits	223
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

K0555_HUMAN
θ value	1.81305 (rank : 1948)	NC score	0.065169 (rank : 1346)
Query Neighborhood Hits	2923	Target Neighborhood Hits	880	Shared Neighborhood Hits	366
SwissProt Accessions	Q96AA8, O60302	Gene names	KIAA0555
Domain Architecture	No domain graphic available
Description	Protein KIAA0555.

K2002_MOUSE
θ value	1.81305 (rank : 1949)	NC score	0.230269 (rank : 1046)
Query Neighborhood Hits	2923	Target Neighborhood Hits	267	Shared Neighborhood Hits	233
SwissProt Accessions	Q69Z38, Q8R365	Gene names	Kiaa2002
Domain Architecture	No domain graphic available
Description	Uncharacterized tyrosine-protein kinase KIAA2002 (EC 2.7.10.2).

KI13A_HUMAN
θ value	1.81305 (rank : 1950)	NC score	0.009366 (rank : 2497)
Query Neighborhood Hits	2923	Target Neighborhood Hits	359	Shared Neighborhood Hits	176
SwissProt Accessions	Q9H1H9, Q9H1H8	Gene names	KIF13A, RBKIN
Domain Architecture
Description	Kinesin-like protein KIF13A (Kinesin-like protein RBKIN).

KIF5A_HUMAN
θ value	1.81305 (rank : 1951)	NC score	0.031963 (rank : 1983)
Query Neighborhood Hits	2923	Target Neighborhood Hits	843	Shared Neighborhood Hits	341
SwissProt Accessions	Q12840, Q4LE26	Gene names	KIF5A, NKHC1
Domain Architecture
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

KIF5C_HUMAN
θ value	1.81305 (rank : 1952)	NC score	0.036695 (rank : 1894)
Query Neighborhood Hits	2923	Target Neighborhood Hits	974	Shared Neighborhood Hits	367
SwissProt Accessions	O60282, O95079	Gene names	KIF5C, KIAA0531, NKHC2
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

KIF5C_MOUSE
θ value	1.81305 (rank : 1953)	NC score	0.038878 (rank : 1860)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1040	Shared Neighborhood Hits	398
SwissProt Accessions	P28738, Q9Z2F8	Gene names	Kif5c, Nkhc2
Domain Architecture
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

KV1G_HUMAN
θ value	1.81305 (rank : 1954)	NC score	-0.000800 (rank : 2870)
Query Neighborhood Hits	2923	Target Neighborhood Hits	241	Shared Neighborhood Hits	77
SwissProt Accessions	P01599	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-I region Gal.

LIRB3_HUMAN
θ value	1.81305 (rank : 1955)	NC score	0.024498 (rank : 2118)
Query Neighborhood Hits	2923	Target Neighborhood Hits	125	Shared Neighborhood Hits	62
SwissProt Accessions	O75022, O15471, Q86U49	Gene names	LILRB3, ILT5, LIR3
Domain Architecture	No domain graphic available
Description	Leukocyte immunoglobulin-like receptor subfamily B member 3 precursor (Leukocyte immunoglobulin-like receptor 3) (LIR-3) (Immunoglobulin- like transcript 5) (ILT-5) (Monocyte inhibitory receptor HL9) (CD85a antigen).

LV4E_HUMAN
θ value	1.81305 (rank : 1956)	NC score	0.001410 (rank : 2785)
Query Neighborhood Hits	2923	Target Neighborhood Hits	218	Shared Neighborhood Hits	72
SwissProt Accessions	P06889	Gene names
Domain Architecture	No domain graphic available
Description	Ig lambda chain V-IV region MOL.

MACF1_HUMAN
θ value	1.81305 (rank : 1957)	NC score	0.042154 (rank : 1810)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1341	Shared Neighborhood Hits	421
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MANS1_MOUSE
θ value	1.81305 (rank : 1958)	NC score	0.011991 (rank : 2416)
Query Neighborhood Hits	2923	Target Neighborhood Hits	19	Shared Neighborhood Hits	9
SwissProt Accessions	Q9CR33, Q80V71	Gene names	Mansc1
Domain Architecture	No domain graphic available
Description	MANSC domain-containing protein 1 precursor.

MEGF9_MOUSE
θ value	1.81305 (rank : 1959)	NC score	0.045593 (rank : 1757)
Query Neighborhood Hits	2923	Target Neighborhood Hits	896	Shared Neighborhood Hits	263
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MY116_MOUSE
θ value	1.81305 (rank : 1960)	NC score	0.019609 (rank : 2212)
Query Neighborhood Hits	2923	Target Neighborhood Hits	70	Shared Neighborhood Hits	32
SwissProt Accessions	P17564	Gene names	Myd116
Domain Architecture	No domain graphic available
Description	Myeloid differentiation primary response protein MyD116.

MYBB_MOUSE
θ value	1.81305 (rank : 1961)	NC score	0.008382 (rank : 2525)
Query Neighborhood Hits	2923	Target Neighborhood Hits	73	Shared Neighborhood Hits	35
SwissProt Accessions	P48972	Gene names	Mybl2, Bmyb
Domain Architecture
Description	Myb-related protein B (B-Myb).

NOTC2_MOUSE
θ value	1.81305 (rank : 1962)	NC score	0.022705 (rank : 2154)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1069	Shared Neighborhood Hits	207
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NP1L3_MOUSE
θ value	1.81305 (rank : 1963)	NC score	0.022367 (rank : 2159)
Query Neighborhood Hits	2923	Target Neighborhood Hits	233	Shared Neighborhood Hits	114
SwissProt Accessions	Q794H2, O54802	Gene names	Nap1l3, Mb20
Domain Architecture	No domain graphic available
Description	Nucleosome assembly protein 1-like 3 (Brain-specific protein MB20).

NUP62_MOUSE
θ value	1.81305 (rank : 1964)	NC score	0.031009 (rank : 1995)
Query Neighborhood Hits	2923	Target Neighborhood Hits	200	Shared Neighborhood Hits	109
SwissProt Accessions	Q63850, Q99JN7	Gene names	Nup62
Domain Architecture
Description	Nuclear pore glycoprotein p62 (62 kDa nucleoporin).

PCDC2_HUMAN
θ value	1.81305 (rank : 1965)	NC score	-0.008293 (rank : 3032)
Query Neighborhood Hits	2923	Target Neighborhood Hits	185	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y5I4, Q9Y5F4	Gene names	PCDHAC2
Domain Architecture
Description	Protocadherin alpha C2 precursor (PCDH-alpha-C2).

PCOC1_HUMAN
θ value	1.81305 (rank : 1966)	NC score	-0.003303 (rank : 2941)
Query Neighborhood Hits	2923	Target Neighborhood Hits	146	Shared Neighborhood Hits	35
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

PECR_HUMAN
θ value	1.81305 (rank : 1967)	NC score	-0.004775 (rank : 2970)
Query Neighborhood Hits	2923	Target Neighborhood Hits	77	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BY49, Q6IAK9, Q9NRD4, Q9NY60, Q9P1A4	Gene names	PECR
Domain Architecture	No domain graphic available
Description	Peroxisomal trans-2-enoyl-CoA reductase (EC 1.3.1.38) (TERP) (HPDHase) (pVI-ARL) (2,4-dienoyl-CoA reductase-related protein) (DCR-RP).

PELP1_HUMAN
θ value	1.81305 (rank : 1968)	NC score	0.051416 (rank : 1674)
Query Neighborhood Hits	2923	Target Neighborhood Hits	596	Shared Neighborhood Hits	303
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

PGCB_MOUSE
θ value	1.81305 (rank : 1969)	NC score	0.010778 (rank : 2449)
Query Neighborhood Hits	2923	Target Neighborhood Hits	459	Shared Neighborhood Hits	113
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

PRP1_HUMAN
θ value	1.81305 (rank : 1970)	NC score	0.079639 (rank : 1265)
Query Neighborhood Hits	2923	Target Neighborhood Hits	385	Shared Neighborhood Hits	190
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PRP5_HUMAN
θ value	1.81305 (rank : 1971)	NC score	0.045649 (rank : 1755)
Query Neighborhood Hits	2923	Target Neighborhood Hits	108	Shared Neighborhood Hits	48
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

PSIP1_HUMAN
θ value	1.81305 (rank : 1972)	NC score	0.023189 (rank : 2143)
Query Neighborhood Hits	2923	Target Neighborhood Hits	341	Shared Neighborhood Hits	157
SwissProt Accessions	O75475, O00256, O95368, Q6P391, Q86YB9, Q9NZI3, Q9UER6	Gene names	PSIP1, DFS70, LEDGF, PSIP2
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (Transcriptional coactivator p75/p52) (Dense fine speckles 70 kDa protein) (DFS 70) (CLL-associated antigen KW-7).

RECQ5_HUMAN
θ value	1.81305 (rank : 1973)	NC score	0.007565 (rank : 2552)
Query Neighborhood Hits	2923	Target Neighborhood Hits	390	Shared Neighborhood Hits	134
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

RN168_HUMAN
θ value	1.81305 (rank : 1974)	NC score	0.006848 (rank : 2577)
Query Neighborhood Hits	2923	Target Neighborhood Hits	370	Shared Neighborhood Hits	103
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RNZ2_HUMAN
θ value	1.81305 (rank : 1975)	NC score	0.004779 (rank : 2649)
Query Neighborhood Hits	2923	Target Neighborhood Hits	17	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BQ52, Q9HAS8, Q9HAS9, Q9NVT1	Gene names	ELAC2, HPC2
Domain Architecture
Description	Zinc phosphodiesterase ELAC protein 2 (EC 3.1.26.11) (Ribonuclease Z 2) (RNase Z 2) (tRNase Z 2) (tRNA 3 endonuclease 2) (ElaC homolog protein 2) (Heredity prostate cancer protein 2).

RPGF1_HUMAN
θ value	1.81305 (rank : 1976)	NC score	0.003688 (rank : 2697)
Query Neighborhood Hits	2923	Target Neighborhood Hits	262	Shared Neighborhood Hits	81
SwissProt Accessions	Q13905	Gene names	RAPGEF1, GRF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP).

RPTN_MOUSE
θ value	1.81305 (rank : 1977)	NC score	0.018198 (rank : 2233)
Query Neighborhood Hits	2923	Target Neighborhood Hits	650	Shared Neighborhood Hits	209
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

RSF1_HUMAN
θ value	1.81305 (rank : 1978)	NC score	0.050029 (rank : 1705)
Query Neighborhood Hits	2923	Target Neighborhood Hits	539	Shared Neighborhood Hits	269
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

RTN1_MOUSE
θ value	1.81305 (rank : 1979)	NC score	0.026762 (rank : 2069)
Query Neighborhood Hits	2923	Target Neighborhood Hits	189	Shared Neighborhood Hits	88
SwissProt Accessions	Q8K0T0, Q8K4S4	Gene names	Rtn1, Nsp
Domain Architecture	No domain graphic available
Description	Reticulon-1 (Neuroendocrine-specific protein).

SCN4B_MOUSE
θ value	1.81305 (rank : 1980)	NC score	0.037947 (rank : 1878)
Query Neighborhood Hits	2923	Target Neighborhood Hits	59	Shared Neighborhood Hits	48
SwissProt Accessions	Q7M729	Gene names	Scn4b
Domain Architecture	No domain graphic available
Description	Sodium channel beta-4 subunit precursor.

SDS3_HUMAN
θ value	1.81305 (rank : 1981)	NC score	0.031257 (rank : 1993)
Query Neighborhood Hits	2923	Target Neighborhood Hits	257	Shared Neighborhood Hits	146
SwissProt Accessions	Q9H7L9, Q8N6H0, Q9H8D2	Gene names	SUDS3, SDS3
Domain Architecture	No domain graphic available
Description	Sin3 histone deacetylase corepressor complex component SDS3 (Suppressor of defective silencing 3 protein homolog).

SDS3_MOUSE
θ value	1.81305 (rank : 1982)	NC score	0.029414 (rank : 2015)
Query Neighborhood Hits	2923	Target Neighborhood Hits	248	Shared Neighborhood Hits	141
SwissProt Accessions	Q8BR65, Q3UC92, Q6P6K1, Q7TNT0, Q8BRR7, Q8K5B4	Gene names	Suds3, Sds3
Domain Architecture	No domain graphic available
Description	Sin3 histone deacetylase corepressor complex component SDS3 (Suppressor of defective silencing 3 protein homolog).

SEM4G_MOUSE
θ value	1.81305 (rank : 1983)	NC score	0.016648 (rank : 2273)
Query Neighborhood Hits	2923	Target Neighborhood Hits	99	Shared Neighborhood Hits	49
SwissProt Accessions	Q9WUH7	Gene names	Sema4g
Domain Architecture
Description	Semaphorin-4G precursor.

SFRS8_HUMAN
θ value	1.81305 (rank : 1984)	NC score	0.033440 (rank : 1961)
Query Neighborhood Hits	2923	Target Neighborhood Hits	166	Shared Neighborhood Hits	81
SwissProt Accessions	Q12872	Gene names	SFRS8, SWAP
Domain Architecture
Description	Splicing factor, arginine/serine-rich 8 (Suppressor of white apricot protein homolog).

SNIP_HUMAN
θ value	1.81305 (rank : 1985)	NC score	0.027269 (rank : 2058)
Query Neighborhood Hits	2923	Target Neighborhood Hits	313	Shared Neighborhood Hits	164
SwissProt Accessions	Q9C0H9, Q8N4W8	Gene names	P140, KIAA1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

SRBP2_HUMAN
θ value	1.81305 (rank : 1986)	NC score	0.004060 (rank : 2676)
Query Neighborhood Hits	2923	Target Neighborhood Hits	133	Shared Neighborhood Hits	31
SwissProt Accessions	Q12772, Q9UH04	Gene names	SREBF2, SREBP2
Domain Architecture
Description	Sterol regulatory element-binding protein 2 (SREBP-2) (Sterol regulatory element-binding transcription factor 2).

SRR_MOUSE
θ value	1.81305 (rank : 1987)	NC score	0.006041 (rank : 2603)
Query Neighborhood Hits	2923	Target Neighborhood Hits	11	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QZX7	Gene names	Srr
Domain Architecture
Description	Serine racemase (EC 5.1.1.-).

STMN1_HUMAN
θ value	1.81305 (rank : 1988)	NC score	0.045108 (rank : 1763)
Query Neighborhood Hits	2923	Target Neighborhood Hits	554	Shared Neighborhood Hits	291
SwissProt Accessions	P16949	Gene names	STMN1, LAP18, OP18
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Protein Pr22).

SUHW2_HUMAN
θ value	1.81305 (rank : 1989)	NC score	-0.025336 (rank : 3091)
Query Neighborhood Hits	2923	Target Neighborhood Hits	683	Shared Neighborhood Hits	60
SwissProt Accessions	Q86YH2	Gene names	SUHW2, ZNF632
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 2 (5'OY11.1) (Zinc finger protein 632).

SYAP1_HUMAN
θ value	1.81305 (rank : 1990)	NC score	0.013754 (rank : 2364)
Query Neighborhood Hits	2923	Target Neighborhood Hits	58	Shared Neighborhood Hits	33
SwissProt Accessions	Q96A49, Q96C60, Q96JQ6, Q96T20	Gene names	SYAP1
Domain Architecture
Description	Synapse-associated protein 1.

TAB3_MOUSE
θ value	1.81305 (rank : 1991)	NC score	0.015936 (rank : 2290)
Query Neighborhood Hits	2923	Target Neighborhood Hits	273	Shared Neighborhood Hits	108
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

TBL1Y_HUMAN
θ value	1.81305 (rank : 1992)	NC score	-0.016313 (rank : 3077)
Query Neighborhood Hits	2923	Target Neighborhood Hits	331	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BQ87	Gene names	TBL1Y, TBL1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1Y (Transducin beta-like 1Y protein) (Transducin-beta-like 1, Y-linked).

TCGAP_HUMAN
θ value	1.81305 (rank : 1993)	NC score	0.006085 (rank : 2600)
Query Neighborhood Hits	2923	Target Neighborhood Hits	872	Shared Neighborhood Hits	230
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TEX14_HUMAN
θ value	1.81305 (rank : 1994)	NC score	0.372602 (rank : 965)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1103	Shared Neighborhood Hits	690
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

TIMD1_MOUSE
θ value	1.81305 (rank : 1995)	NC score	0.042424 (rank : 1806)
Query Neighborhood Hits	2923	Target Neighborhood Hits	97	Shared Neighborhood Hits	69
SwissProt Accessions	Q5QNS5, Q7TPU2, Q8VIM1, Q8VIM2	Gene names	Havcr1, Tim1, Timd1
Domain Architecture	No domain graphic available
Description	Hepatitis A virus cellular receptor 1 homolog precursor (HAVcr-1) (T cell immunoglobulin and mucin domain-containing protein 1) (TIMD-1) (T cell membrane protein 1) (TIM-1).

TNR3_HUMAN
θ value	1.81305 (rank : 1996)	NC score	-0.000962 (rank : 2877)
Query Neighborhood Hits	2923	Target Neighborhood Hits	145	Shared Neighborhood Hits	34
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

TOPK_MOUSE
θ value	1.81305 (rank : 1997)	NC score	0.478238 (rank : 877)
Query Neighborhood Hits	2923	Target Neighborhood Hits	618	Shared Neighborhood Hits	559
SwissProt Accessions	Q9JJ78, Q922V2, Q9D184	Gene names	Pbk, Topk
Domain Architecture	No domain graphic available
Description	T-lymphokine-activated killer cell-originated protein kinase (EC 2.7.12.2) (T-LAK cell-originated protein kinase) (PDZ-binding kinase).

TR95_MOUSE
θ value	1.81305 (rank : 1998)	NC score	0.003397 (rank : 2711)
Query Neighborhood Hits	2923	Target Neighborhood Hits	95	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PGF3	Gene names	Thrap5
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein complex 95 kDa component (Trap95) (Thyroid hormone receptor-associated protein 5) (Vitamin D3 receptor-interacting protein complex component DRIP92).

TROP_HUMAN
θ value	1.81305 (rank : 1999)	NC score	-0.002939 (rank : 2933)
Query Neighborhood Hits	2923	Target Neighborhood Hits	158	Shared Neighborhood Hits	26
SwissProt Accessions	Q12816, Q9NU89, Q9UPN8	Gene names	TRO, KIAA1114, MAGED3
Domain Architecture
Description	Trophinin (MAGE-D3 antigen).

TRPM6_MOUSE
θ value	1.81305 (rank : 2000)	NC score	-0.001540 (rank : 2897)
Query Neighborhood Hits	2923	Target Neighborhood Hits	78	Shared Neighborhood Hits	22
SwissProt Accessions	Q8CIR4	Gene names	Trpm6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6).

TTC28_HUMAN
θ value	1.81305 (rank : 2001)	NC score	0.010005 (rank : 2471)
Query Neighborhood Hits	2923	Target Neighborhood Hits	271	Shared Neighborhood Hits	93
SwissProt Accessions	Q96AY4, O95928, O95929, Q9NTE4, Q9UG31, Q9UGG5, Q9UPV8, Q9Y3S5	Gene names	TTC28, KIAA1043
Domain Architecture
Description	Tetratricopeptide repeat protein 28 (TPR repeat protein 28).

TTLL2_HUMAN
θ value	1.81305 (rank : 2002)	NC score	0.002284 (rank : 2754)
Query Neighborhood Hits	2923	Target Neighborhood Hits	23	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BWV7, Q7Z6R8, Q86X22	Gene names	TTLL2, C6orf104
Domain Architecture
Description	Tubulin--tyrosine ligase-like protein 2 (Testis-specific protein NYD- TSPG).

TVA3_MOUSE
θ value	1.81305 (rank : 2003)	NC score	0.000620 (rank : 2820)
Query Neighborhood Hits	2923	Target Neighborhood Hits	192	Shared Neighborhood Hits	59
SwissProt Accessions	P06323	Gene names
Domain Architecture	No domain graphic available
Description	T-cell receptor alpha chain V region CTL-F3 precursor.

TXD11_MOUSE
θ value	1.81305 (rank : 2004)	NC score	0.007527 (rank : 2554)
Query Neighborhood Hits	2923	Target Neighborhood Hits	81	Shared Neighborhood Hits	27
SwissProt Accessions	Q8K2W3, Q8BMR8, Q8VCK9	Gene names	Txndc11
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 11.

TXLNA_HUMAN
θ value	1.81305 (rank : 2005)	NC score	0.052270 (rank : 1655)
Query Neighborhood Hits	2923	Target Neighborhood Hits	982	Shared Neighborhood Hits	398
SwissProt Accessions	P40222, Q66K62, Q86T54, Q86T85, Q86T86, Q86Y86, Q86YW3, Q8N2Y3	Gene names	TXLNA, TXLN
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

UROL1_MOUSE
θ value	1.81305 (rank : 2006)	NC score	0.014621 (rank : 2336)
Query Neighborhood Hits	2923	Target Neighborhood Hits	235	Shared Neighborhood Hits	60
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

ZBT26_HUMAN
θ value	1.81305 (rank : 2007)	NC score	-0.030585 (rank : 3126)
Query Neighborhood Hits	2923	Target Neighborhood Hits	784	Shared Neighborhood Hits	68
SwissProt Accessions	Q9HCK0, Q8WTR1	Gene names	ZBTB26, KIAA1572, ZNF481
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 26 (Zinc finger protein 481) (Zinc finger protein Bioref).

ZBTB9_MOUSE
θ value	1.81305 (rank : 2008)	NC score	-0.026129 (rank : 3092)
Query Neighborhood Hits	2923	Target Neighborhood Hits	780	Shared Neighborhood Hits	68
SwissProt Accessions	Q8CDC7, Q3U3B2, Q9CYQ0	Gene names	Zbtb9
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 9.

5NT1B_MOUSE
θ value	2.36792 (rank : 2009)	NC score	0.012581 (rank : 2395)
Query Neighborhood Hits	2923	Target Neighborhood Hits	78	Shared Neighborhood Hits	46
SwissProt Accessions	Q91YE9, Q91Y48	Gene names	Nt5c1b, Airp
Domain Architecture
Description	Cytosolic 5'-nucleotidase 1B (EC 3.1.3.5) (Cytosolic 5'-nucleotidase IB) (cN1B) (cN-IB) (Autoimmune infertility-related protein).

AFF4_HUMAN
θ value	2.36792 (rank : 2010)	NC score	0.039355 (rank : 1849)
Query Neighborhood Hits	2923	Target Neighborhood Hits	611	Shared Neighborhood Hits	238
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

AKAP4_HUMAN
θ value	2.36792 (rank : 2011)	NC score	0.002442 (rank : 2747)
Query Neighborhood Hits	2923	Target Neighborhood Hits	33	Shared Neighborhood Hits	9
SwissProt Accessions	Q5JQC9, O60904, O95246, Q5JQD1, Q5JQD2, Q5JQD3	Gene names	AKAP4, AKAP82
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 4 precursor (Protein kinase A-anchoring protein 4) (PRKA4) (A-kinase anchor protein 82 kDa) (AKAP 82) (hAKAP82) (Major sperm fibrous sheath protein) (HI).

ANF_HUMAN
θ value	2.36792 (rank : 2012)	NC score	0.008016 (rank : 2540)
Query Neighborhood Hits	2923	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	P01160, Q13766	Gene names	NPPA, PND
Domain Architecture
Description	Atrial natriuretic factor precursor (ANF) (Atrial natriuretic peptide) (ANP) (Prepronatriodilatin) (CDD-ANF) [Contains: Cardiodilatin-related peptide (CDP)].

ANGL3_HUMAN
θ value	2.36792 (rank : 2013)	NC score	0.035636 (rank : 1914)
Query Neighborhood Hits	2923	Target Neighborhood Hits	289	Shared Neighborhood Hits	141
SwissProt Accessions	Q9Y5C1	Gene names	ANGPTL3, ANGPT5
Domain Architecture
Description	Angiopoietin-related protein 3 precursor (Angiopoietin-like 3) (Angiopoietin-5) (ANG-5).

ANR38_MOUSE
θ value	2.36792 (rank : 2014)	NC score	0.020583 (rank : 2193)
Query Neighborhood Hits	2923	Target Neighborhood Hits	512	Shared Neighborhood Hits	194
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

ASPH_HUMAN
θ value	2.36792 (rank : 2015)	NC score	0.017793 (rank : 2242)
Query Neighborhood Hits	2923	Target Neighborhood Hits	158	Shared Neighborhood Hits	57
SwissProt Accessions	Q12797	Gene names	ASPH
Domain Architecture
Description	Aspartyl/asparaginyl beta-hydroxylase (EC 1.14.11.16) (Aspartate beta- hydroxylase) (ASP beta-hydroxylase) (Peptide-aspartate beta- dioxygenase).

AT2A3_HUMAN
θ value	2.36792 (rank : 2016)	NC score	-0.005785 (rank : 2991)
Query Neighborhood Hits	2923	Target Neighborhood Hits	71	Shared Neighborhood Hits	5
SwissProt Accessions	Q93084, O60900, O60901, O75501, O75502, Q16115, Q8TEX5, Q8TEX6	Gene names	ATP2A3
Domain Architecture
Description	Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 (EC 3.6.3.8) (Calcium pump 3) (SERCA3) (SR Ca(2+)-ATPase 3).

AT2A3_MOUSE
θ value	2.36792 (rank : 2017)	NC score	-0.005621 (rank : 2988)
Query Neighborhood Hits	2923	Target Neighborhood Hits	73	Shared Neighborhood Hits	10
SwissProt Accessions	Q64518, O70625, Q64517	Gene names	Atp2a3
Domain Architecture
Description	Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 (EC 3.6.3.8) (Calcium pump 3) (SERCA3) (SR Ca(2+)-ATPase 3).

AZI1_MOUSE
θ value	2.36792 (rank : 2018)	NC score	0.057080 (rank : 1525)
Query Neighborhood Hits	2923	Target Neighborhood Hits	990	Shared Neighborhood Hits	396
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

CALR_HUMAN
θ value	2.36792 (rank : 2019)	NC score	0.007729 (rank : 2548)
Query Neighborhood Hits	2923	Target Neighborhood Hits	85	Shared Neighborhood Hits	37
SwissProt Accessions	P27797	Gene names	CALR, CRTC
Domain Architecture
Description	Calreticulin precursor (CRP55) (Calregulin) (HACBP) (ERp60) (grp60).

CBL_MOUSE
θ value	2.36792 (rank : 2020)	NC score	0.009530 (rank : 2486)
Query Neighborhood Hits	2923	Target Neighborhood Hits	426	Shared Neighborhood Hits	120
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

CCD39_HUMAN
θ value	2.36792 (rank : 2021)	NC score	0.057314 (rank : 1512)
Query Neighborhood Hits	2923	Target Neighborhood Hits	868	Shared Neighborhood Hits	350
SwissProt Accessions	Q9UFE4	Gene names	CCDC39
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

CCD41_MOUSE
θ value	2.36792 (rank : 2022)	NC score	0.063575 (rank : 1364)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1399	Shared Neighborhood Hits	490
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

CCNL1_HUMAN
θ value	2.36792 (rank : 2023)	NC score	0.004853 (rank : 2644)
Query Neighborhood Hits	2923	Target Neighborhood Hits	79	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UK58, Q6NVY9, Q6UWS7, Q8NI48, Q96QT0, Q9NZF3	Gene names	CCNL1
Domain Architecture	No domain graphic available
Description	Cyclin-L1 (Cyclin-L).

CD4_MOUSE
θ value	2.36792 (rank : 2024)	NC score	0.040653 (rank : 1835)
Query Neighborhood Hits	2923	Target Neighborhood Hits	41	Shared Neighborhood Hits	30
SwissProt Accessions	P06332	Gene names	Cd4
Domain Architecture
Description	T-cell surface glycoprotein CD4 precursor (T-cell surface antigen T4/Leu-3) (T-cell differentiation antigen L3T4).

CD79A_MOUSE
θ value	2.36792 (rank : 2025)	NC score	0.022523 (rank : 2157)
Query Neighborhood Hits	2923	Target Neighborhood Hits	17	Shared Neighborhood Hits	16
SwissProt Accessions	P11911	Gene names	Cd79a, Iga, Mb-1
Domain Architecture
Description	B-cell antigen receptor complex-associated protein alpha-chain precursor (IG-alpha) (MB-1 membrane glycoprotein) (Surface IgM- associated protein) (Membrane-bound immunoglobulin-associated protein) (CD79a antigen).

CD86_MOUSE
θ value	2.36792 (rank : 2026)	NC score	0.063210 (rank : 1370)
Query Neighborhood Hits	2923	Target Neighborhood Hits	85	Shared Neighborhood Hits	75
SwissProt Accessions	P42082	Gene names	Cd86
Domain Architecture
Description	T-lymphocyte activation antigen CD86 precursor (Activation B7-2 antigen) (Early T-cell costimulatory molecule 1) (ETC-1).

CE152_HUMAN
θ value	2.36792 (rank : 2027)	NC score	0.061373 (rank : 1406)
Query Neighborhood Hits	2923	Target Neighborhood Hits	976	Shared Neighborhood Hits	389
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

CE290_HUMAN
θ value	2.36792 (rank : 2028)	NC score	0.059339 (rank : 1460)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1553	Shared Neighborhood Hits	511
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

CENPQ_MOUSE
θ value	2.36792 (rank : 2029)	NC score	0.022412 (rank : 2158)
Query Neighborhood Hits	2923	Target Neighborhood Hits	160	Shared Neighborhood Hits	100
SwissProt Accessions	Q9CPQ5, Q8C2G4, Q8VEF8, Q9CX70	Gene names	Cenpq
Domain Architecture	No domain graphic available
Description	Centromere protein Q (CENP-Q).

CEP35_HUMAN
θ value	2.36792 (rank : 2030)	NC score	0.057150 (rank : 1523)
Query Neighborhood Hits	2923	Target Neighborhood Hits	811	Shared Neighborhood Hits	383
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

CI093_HUMAN
θ value	2.36792 (rank : 2031)	NC score	0.061958 (rank : 1394)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1088	Shared Neighborhood Hits	418
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

CJ068_HUMAN
θ value	2.36792 (rank : 2032)	NC score	0.049925 (rank : 1708)
Query Neighborhood Hits	2923	Target Neighborhood Hits	316	Shared Neighborhood Hits	177
SwissProt Accessions	Q9H943, Q8N7T7	Gene names	C10orf68
Domain Architecture	No domain graphic available
Description	Protein C10orf68.

COFA1_MOUSE
θ value	2.36792 (rank : 2033)	NC score	0.014921 (rank : 2325)
Query Neighborhood Hits	2923	Target Neighborhood Hits	305	Shared Neighborhood Hits	88
SwissProt Accessions	O35206, Q9EQD9	Gene names	Col15a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV)].

COG8_MOUSE
θ value	2.36792 (rank : 2034)	NC score	0.007800 (rank : 2546)
Query Neighborhood Hits	2923	Target Neighborhood Hits	147	Shared Neighborhood Hits	50
SwissProt Accessions	Q9JJA2	Gene names	Cog8
Domain Architecture
Description	Conserved oligomeric Golgi complex component 8.

COIA1_MOUSE
θ value	2.36792 (rank : 2035)	NC score	0.016527 (rank : 2277)
Query Neighborhood Hits	2923	Target Neighborhood Hits	481	Shared Neighborhood Hits	143
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

CT116_MOUSE
θ value	2.36792 (rank : 2036)	NC score	0.034783 (rank : 1933)
Query Neighborhood Hits	2923	Target Neighborhood Hits	268	Shared Neighborhood Hits	151
SwissProt Accessions	Q80WW9, Q9CT52	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf116 homolog precursor.

CXXC6_HUMAN
θ value	2.36792 (rank : 2037)	NC score	0.017022 (rank : 2262)
Query Neighborhood Hits	2923	Target Neighborhood Hits	180	Shared Neighborhood Hits	71
SwissProt Accessions	Q8NFU7, Q5VUP7, Q7Z6B6, Q8TCR1, Q9C0I7	Gene names	CXXC6, KIAA1676, LCX
Domain Architecture	No domain graphic available
Description	CXXC-type zinc finger protein 6 (Leukemia-associated protein with a CXXC domain).

DDEF2_HUMAN
θ value	2.36792 (rank : 2038)	NC score	0.006718 (rank : 2580)
Query Neighborhood Hits	2923	Target Neighborhood Hits	599	Shared Neighborhood Hits	176
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DHX40_HUMAN
θ value	2.36792 (rank : 2039)	NC score	-0.000260 (rank : 2849)
Query Neighborhood Hits	2923	Target Neighborhood Hits	34	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IX18, Q5JPH4, Q8TC86, Q8WY53, Q9BXM1, Q9H6M9	Gene names	DHX40, DDX40
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX40 (EC 3.6.1.-) (DEAH box protein 40) (ARG147) (Protein PAD).

DHX40_MOUSE
θ value	2.36792 (rank : 2040)	NC score	-0.000105 (rank : 2843)
Query Neighborhood Hits	2923	Target Neighborhood Hits	40	Shared Neighborhood Hits	15
SwissProt Accessions	Q6PE54, Q8BPH2, Q8CD88, Q9CWN3	Gene names	Dhx40
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX40 (EC 3.6.1.-) (DEAH box protein 40).

DIAP2_HUMAN
θ value	2.36792 (rank : 2041)	NC score	0.017254 (rank : 2257)
Query Neighborhood Hits	2923	Target Neighborhood Hits	342	Shared Neighborhood Hits	176
SwissProt Accessions	O60879, O60878, Q8WX06, Q8WX48, Q9UJL2	Gene names	DIAPH2, DIA
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2).

DPOLA_MOUSE
θ value	2.36792 (rank : 2042)	NC score	0.005263 (rank : 2620)
Query Neighborhood Hits	2923	Target Neighborhood Hits	56	Shared Neighborhood Hits	22
SwissProt Accessions	P33609	Gene names	Pola1, Pola
Domain Architecture
Description	DNA polymerase alpha catalytic subunit (EC 2.7.7.7).

EHMT2_MOUSE
θ value	2.36792 (rank : 2043)	NC score	0.008293 (rank : 2528)
Query Neighborhood Hits	2923	Target Neighborhood Hits	750	Shared Neighborhood Hits	183
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

EMSY_HUMAN
θ value	2.36792 (rank : 2044)	NC score	0.036934 (rank : 1891)
Query Neighborhood Hits	2923	Target Neighborhood Hits	296	Shared Neighborhood Hits	132
SwissProt Accessions	Q7Z589, Q4G109, Q8NBU6, Q8TE50, Q9H8I9, Q9NRH0	Gene names	EMSY, C11orf30
Domain Architecture
Description	Protein EMSY.

ERMAP_MOUSE
θ value	2.36792 (rank : 2045)	NC score	0.032802 (rank : 1974)
Query Neighborhood Hits	2923	Target Neighborhood Hits	231	Shared Neighborhood Hits	118
SwissProt Accessions	Q9JLN5, Q3UV82, Q6P4T5, Q8CEH1	Gene names	Ermap
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor.

FAN_MOUSE
θ value	2.36792 (rank : 2046)	NC score	-0.011353 (rank : 3061)
Query Neighborhood Hits	2923	Target Neighborhood Hits	292	Shared Neighborhood Hits	25
SwissProt Accessions	O35242	Gene names	Nsmaf, Fan
Domain Architecture
Description	Protein FAN (Factor associated with N-SMase activation) (Factor associated with neutral sphingomyelinase activation).

FMNL_MOUSE
θ value	2.36792 (rank : 2047)	NC score	0.028322 (rank : 2044)
Query Neighborhood Hits	2923	Target Neighborhood Hits	428	Shared Neighborhood Hits	230
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

GBP1_HUMAN
θ value	2.36792 (rank : 2048)	NC score	0.028903 (rank : 2028)
Query Neighborhood Hits	2923	Target Neighborhood Hits	339	Shared Neighborhood Hits	199
SwissProt Accessions	P32455	Gene names	GBP1
Domain Architecture
Description	Interferon-induced guanylate-binding protein 1 (GTP-binding protein 1) (Guanine nucleotide-binding protein 1) (GBP-1) (HuGBP-1).

GFPT2_MOUSE
θ value	2.36792 (rank : 2049)	NC score	0.003630 (rank : 2700)
Query Neighborhood Hits	2923	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z2Z9	Gene names	Gfpt2
Domain Architecture
Description	Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 2 (EC 2.6.1.16) (Hexosephosphate aminotransferase 2) (D-fructose-6- phosphate amidotransferase 2) (GFAT 2) (GFAT2).

GP152_MOUSE
θ value	2.36792 (rank : 2050)	NC score	-0.011227 (rank : 3059)
Query Neighborhood Hits	2923	Target Neighborhood Hits	607	Shared Neighborhood Hits	104
SwissProt Accessions	Q8BXS7	Gene names	Gpr152
Domain Architecture
Description	Probable G-protein coupled receptor 152.

GPS2_HUMAN
θ value	2.36792 (rank : 2051)	NC score	0.042595 (rank : 1802)
Query Neighborhood Hits	2923	Target Neighborhood Hits	459	Shared Neighborhood Hits	204
SwissProt Accessions	Q13227	Gene names	GPS2
Domain Architecture	No domain graphic available
Description	G protein pathway suppressor 2 (Protein GPS2).

GPVI_HUMAN
θ value	2.36792 (rank : 2052)	NC score	0.017398 (rank : 2252)
Query Neighborhood Hits	2923	Target Neighborhood Hits	68	Shared Neighborhood Hits	45
SwissProt Accessions	Q9HCN6, Q9HCN7, Q9UIF2	Gene names	GP6, GPVI
Domain Architecture	No domain graphic available
Description	Platelet glycoprotein VI precursor.

HA21_MOUSE
θ value	2.36792 (rank : 2053)	NC score	-0.001503 (rank : 2896)
Query Neighborhood Hits	2923	Target Neighborhood Hits	192	Shared Neighborhood Hits	42
SwissProt Accessions	P01904	Gene names	H2-Ea
Domain Architecture
Description	H-2 class II histocompatibility antigen, E-D alpha chain precursor (H2-IE-alpha).

HA22_MOUSE
θ value	2.36792 (rank : 2054)	NC score	-0.001642 (rank : 2902)
Query Neighborhood Hits	2923	Target Neighborhood Hits	193	Shared Neighborhood Hits	43
SwissProt Accessions	P04224, Q31157	Gene names
Domain Architecture
Description	H-2 class II histocompatibility antigen, E-K alpha chain precursor.

HM20A_HUMAN
θ value	2.36792 (rank : 2055)	NC score	0.014723 (rank : 2332)
Query Neighborhood Hits	2923	Target Neighborhood Hits	343	Shared Neighborhood Hits	155
SwissProt Accessions	Q9NP66, Q53G31, Q9NSF6	Gene names	HMG20A, HMGX1
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (HMG domain-containing protein HMGX1).

HPLN3_HUMAN
θ value	2.36792 (rank : 2056)	NC score	0.020870 (rank : 2185)
Query Neighborhood Hits	2923	Target Neighborhood Hits	70	Shared Neighborhood Hits	54
SwissProt Accessions	Q96S86	Gene names	HAPLN3
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 3 precursor.

ICAM3_HUMAN
θ value	2.36792 (rank : 2057)	NC score	0.110128 (rank : 1183)
Query Neighborhood Hits	2923	Target Neighborhood Hits	100	Shared Neighborhood Hits	90
SwissProt Accessions	P32942	Gene names	ICAM3
Domain Architecture
Description	Intercellular adhesion molecule 3 precursor (ICAM-3) (ICAM-R) (CDw50) (CD50 antigen).

IDH3A_MOUSE
θ value	2.36792 (rank : 2058)	NC score	0.003642 (rank : 2699)
Query Neighborhood Hits	2923	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D6R2, Q3UAM8, Q8C8A1, Q9D1L1	Gene names	Idh3a
Domain Architecture	No domain graphic available
Description	Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH).

IGHE_MOUSE
θ value	2.36792 (rank : 2059)	NC score	0.022869 (rank : 2150)
Query Neighborhood Hits	2923	Target Neighborhood Hits	209	Shared Neighborhood Hits	54
SwissProt Accessions	P06336, P01856	Gene names
Domain Architecture
Description	Ig epsilon chain C region.

IL21R_MOUSE
θ value	2.36792 (rank : 2060)	NC score	0.009691 (rank : 2480)
Query Neighborhood Hits	2923	Target Neighborhood Hits	43	Shared Neighborhood Hits	23
SwissProt Accessions	Q9JHX3, Q9ESM1	Gene names	Il21r, Nilr
Domain Architecture	No domain graphic available
Description	Interleukin-21 receptor precursor (IL-21R) (Novel interleukin receptor) (Lymphocyte receptor beta) (LR-beta) (Novel cytokine receptor NR8).

ILK1_HUMAN
θ value	2.36792 (rank : 2061)	NC score	0.345598 (rank : 980)
Query Neighborhood Hits	2923	Target Neighborhood Hits	857	Shared Neighborhood Hits	567
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

ILK2_HUMAN
θ value	2.36792 (rank : 2062)	NC score	0.335641 (rank : 986)
Query Neighborhood Hits	2923	Target Neighborhood Hits	848	Shared Neighborhood Hits	562
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

ILK_MOUSE
θ value	2.36792 (rank : 2063)	NC score	0.343798 (rank : 982)
Query Neighborhood Hits	2923	Target Neighborhood Hits	858	Shared Neighborhood Hits	568
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

IRAK2_HUMAN
θ value	2.36792 (rank : 2064)	NC score	0.518540 (rank : 819)
Query Neighborhood Hits	2923	Target Neighborhood Hits	714	Shared Neighborhood Hits	654
SwissProt Accessions	O43187	Gene names	IRAK2
Domain Architecture
Description	Interleukin-1 receptor-associated kinase-like 2 (IRAK-2).

JHD2A_MOUSE
θ value	2.36792 (rank : 2065)	NC score	0.006293 (rank : 2594)
Query Neighborhood Hits	2923	Target Neighborhood Hits	123	Shared Neighborhood Hits	53
SwissProt Accessions	Q6PCM1, Q2MJQ6, Q3TKW8, Q3UML3, Q6ZQ57, Q8K2J6, Q8K2K4, Q8R350	Gene names	Jmjd1a, Jhdm2a, Kiaa0742
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2A (EC 1.14.11.-) (Jumonji domain-containing protein 1A).

K1196_HUMAN
θ value	2.36792 (rank : 2066)	NC score	-0.003563 (rank : 2951)
Query Neighborhood Hits	2923	Target Neighborhood Hits	618	Shared Neighborhood Hits	78
SwissProt Accessions	Q96KM6, Q9ULM4	Gene names	KIAA1196
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1196.

KCNQ3_HUMAN
θ value	2.36792 (rank : 2067)	NC score	-0.004969 (rank : 2975)
Query Neighborhood Hits	2923	Target Neighborhood Hits	114	Shared Neighborhood Hits	16
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KIF2C_HUMAN
θ value	2.36792 (rank : 2068)	NC score	0.003017 (rank : 2726)
Query Neighborhood Hits	2923	Target Neighborhood Hits	138	Shared Neighborhood Hits	62
SwissProt Accessions	Q99661, Q96C18, Q96HB8, Q9BWV8	Gene names	KIF2C, KNSL6
Domain Architecture
Description	Kinesin-like protein KIF2C (Mitotic centromere-associated kinesin) (MCAK) (Kinesin-like protein 6).

KIF5A_MOUSE
θ value	2.36792 (rank : 2069)	NC score	0.031735 (rank : 1988)
Query Neighborhood Hits	2923	Target Neighborhood Hits	859	Shared Neighborhood Hits	341
SwissProt Accessions	P33175, Q5DTP1, Q6PDY7, Q9Z2F9	Gene names	Kif5a, Kiaa4086, Kif5, Nkhc1
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

KV1B_HUMAN
θ value	2.36792 (rank : 2070)	NC score	-0.003361 (rank : 2943)
Query Neighborhood Hits	2923	Target Neighborhood Hits	244	Shared Neighborhood Hits	68
SwissProt Accessions	P01594	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-I region AU.

KV3H_MOUSE
θ value	2.36792 (rank : 2071)	NC score	-0.004278 (rank : 2959)
Query Neighborhood Hits	2923	Target Neighborhood Hits	243	Shared Neighborhood Hits	70
SwissProt Accessions	P01660	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-III region PC 3741/TEPC 111.

KV3K_HUMAN
θ value	2.36792 (rank : 2072)	NC score	0.000360 (rank : 2829)
Query Neighborhood Hits	2923	Target Neighborhood Hits	279	Shared Neighborhood Hits	84
SwissProt Accessions	P06311	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-III region IARC/BL41 precursor.

KV5D_MOUSE
θ value	2.36792 (rank : 2073)	NC score	0.002108 (rank : 2760)
Query Neighborhood Hits	2923	Target Neighborhood Hits	255	Shared Neighborhood Hits	90
SwissProt Accessions	P01636	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-V region MOPC 149.

KV5S_MOUSE
θ value	2.36792 (rank : 2074)	NC score	-0.004623 (rank : 2967)
Query Neighborhood Hits	2923	Target Neighborhood Hits	243	Shared Neighborhood Hits	67
SwissProt Accessions	P01652	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-V region J606.

LAMA5_HUMAN
θ value	2.36792 (rank : 2075)	NC score	0.044349 (rank : 1770)
Query Neighborhood Hits	2923	Target Neighborhood Hits	976	Shared Neighborhood Hits	298
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LEUK_HUMAN
θ value	2.36792 (rank : 2076)	NC score	0.025756 (rank : 2093)
Query Neighborhood Hits	2923	Target Neighborhood Hits	213	Shared Neighborhood Hits	90
SwissProt Accessions	P16150	Gene names	SPN, CD43
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Galactoglycoprotein) (GALGP) (CD43 antigen).

MNT_HUMAN
θ value	2.36792 (rank : 2077)	NC score	0.041419 (rank : 1823)
Query Neighborhood Hits	2923	Target Neighborhood Hits	496	Shared Neighborhood Hits	219
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MYH6_HUMAN
θ value	2.36792 (rank : 2078)	NC score	0.052552 (rank : 1647)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1426	Shared Neighborhood Hits	467
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH6_MOUSE
θ value	2.36792 (rank : 2079)	NC score	0.053832 (rank : 1620)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1501	Shared Neighborhood Hits	488
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH7_HUMAN
θ value	2.36792 (rank : 2080)	NC score	0.053649 (rank : 1625)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1559	Shared Neighborhood Hits	493
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

MYP0_HUMAN
θ value	2.36792 (rank : 2081)	NC score	0.037632 (rank : 1881)
Query Neighborhood Hits	2923	Target Neighborhood Hits	58	Shared Neighborhood Hits	46
SwissProt Accessions	P25189, Q16072, Q92677, Q9BR67	Gene names	MPZ
Domain Architecture
Description	Myelin P0 protein precursor (Myelin protein zero) (Myelin peripheral protein) (MPP).

MYP0_MOUSE
θ value	2.36792 (rank : 2082)	NC score	0.035562 (rank : 1916)
Query Neighborhood Hits	2923	Target Neighborhood Hits	60	Shared Neighborhood Hits	46
SwissProt Accessions	P27573	Gene names	Mpz, P0
Domain Architecture
Description	Myelin P0 protein precursor (Myelin protein zero) (Myelin peripheral protein) (MPP).

NLGN3_MOUSE
θ value	2.36792 (rank : 2083)	NC score	-0.000538 (rank : 2861)
Query Neighborhood Hits	2923	Target Neighborhood Hits	48	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BYM5, Q8BXR4	Gene names	Nlgn3
Domain Architecture
Description	Neuroligin-3 precursor (Gliotactin homolog).

NMI_HUMAN
θ value	2.36792 (rank : 2084)	NC score	0.009291 (rank : 2500)
Query Neighborhood Hits	2923	Target Neighborhood Hits	102	Shared Neighborhood Hits	54
SwissProt Accessions	Q13287, Q53TI8, Q9BVE5	Gene names	NMI
Domain Architecture
Description	N-myc-interactor (Nmi) (N-myc and STAT interactor).

NOL1_HUMAN
θ value	2.36792 (rank : 2085)	NC score	0.014943 (rank : 2323)
Query Neighborhood Hits	2923	Target Neighborhood Hits	74	Shared Neighborhood Hits	33
SwissProt Accessions	P46087	Gene names	NOL1
Domain Architecture
Description	Proliferating-cell nucleolar antigen p120 (Proliferation-associated nucleolar protein p120).

NUMA1_HUMAN
θ value	2.36792 (rank : 2086)	NC score	0.058430 (rank : 1482)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1523	Shared Neighborhood Hits	504
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

NUMBL_HUMAN
θ value	2.36792 (rank : 2087)	NC score	0.009360 (rank : 2498)
Query Neighborhood Hits	2923	Target Neighborhood Hits	394	Shared Neighborhood Hits	130
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

OS9_HUMAN
θ value	2.36792 (rank : 2088)	NC score	0.017683 (rank : 2246)
Query Neighborhood Hits	2923	Target Neighborhood Hits	134	Shared Neighborhood Hits	66
SwissProt Accessions	Q13438, O00579	Gene names	OS9
Domain Architecture	No domain graphic available
Description	Protein OS-9 precursor (Amplified in osteosarcoma 9).

PCD19_HUMAN
θ value	2.36792 (rank : 2089)	NC score	-0.008431 (rank : 3038)
Query Neighborhood Hits	2923	Target Neighborhood Hits	164	Shared Neighborhood Hits	34
SwissProt Accessions	Q8TAB3, Q5JTG1, Q5JTG2, Q68DT7, Q9P2N3	Gene names	PCDH19, KIAA1313
Domain Architecture
Description	Protocadherin-19 precursor.

PDZD1_MOUSE
θ value	2.36792 (rank : 2090)	NC score	0.007384 (rank : 2556)
Query Neighborhood Hits	2923	Target Neighborhood Hits	191	Shared Neighborhood Hits	43
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

PKD1_HUMAN
θ value	2.36792 (rank : 2091)	NC score	0.034468 (rank : 1942)
Query Neighborhood Hits	2923	Target Neighborhood Hits	387	Shared Neighborhood Hits	85
SwissProt Accessions	P98161, Q15140, Q15141	Gene names	PKD1
Domain Architecture
Description	Polycystin-1 precursor (Autosomal dominant polycystic kidney disease protein 1).

PML_MOUSE
θ value	2.36792 (rank : 2092)	NC score	0.010468 (rank : 2456)
Query Neighborhood Hits	2923	Target Neighborhood Hits	246	Shared Neighborhood Hits	80
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

R113B_HUMAN
θ value	2.36792 (rank : 2093)	NC score	0.000547 (rank : 2823)
Query Neighborhood Hits	2923	Target Neighborhood Hits	165	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

RAI1_MOUSE
θ value	2.36792 (rank : 2094)	NC score	0.021853 (rank : 2171)
Query Neighborhood Hits	2923	Target Neighborhood Hits	344	Shared Neighborhood Hits	129
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

RENT2_HUMAN
θ value	2.36792 (rank : 2095)	NC score	0.047345 (rank : 1736)
Query Neighborhood Hits	2923	Target Neighborhood Hits	618	Shared Neighborhood Hits	288
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

RIMB1_HUMAN
θ value	2.36792 (rank : 2096)	NC score	0.083262 (rank : 1253)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1479	Shared Neighborhood Hits	551
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RIPK2_MOUSE
θ value	2.36792 (rank : 2097)	NC score	0.573219 (rank : 699)
Query Neighborhood Hits	2923	Target Neighborhood Hits	776	Shared Neighborhood Hits	707
SwissProt Accessions	P58801	Gene names	Ripk2
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1).

RN168_MOUSE
θ value	2.36792 (rank : 2098)	NC score	0.018021 (rank : 2237)
Query Neighborhood Hits	2923	Target Neighborhood Hits	440	Shared Neighborhood Hits	153
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RP1L1_MOUSE
θ value	2.36792 (rank : 2099)	NC score	0.036960 (rank : 1890)
Query Neighborhood Hits	2923	Target Neighborhood Hits	170	Shared Neighborhood Hits	61
SwissProt Accessions	Q8CGM2, Q8K0I4	Gene names	Rp1l1, Rp1hl1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein (Retinitis pigmentosa 1-like protein 1).

S19BP_HUMAN
θ value	2.36792 (rank : 2100)	NC score	0.008748 (rank : 2514)
Query Neighborhood Hits	2923	Target Neighborhood Hits	13	Shared Neighborhood Hits	5
SwissProt Accessions	Q86WX3, Q5JZA1	Gene names	RPS19BP1
Domain Architecture	No domain graphic available
Description	40S ribosomal protein S19-binding protein 1 (RPS19-binding protein 1) (S19BP).

SASH1_MOUSE
θ value	2.36792 (rank : 2101)	NC score	0.029928 (rank : 2003)
Query Neighborhood Hits	2923	Target Neighborhood Hits	263	Shared Neighborhood Hits	114
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

SEM3E_MOUSE
θ value	2.36792 (rank : 2102)	NC score	0.008017 (rank : 2539)
Query Neighborhood Hits	2923	Target Neighborhood Hits	76	Shared Neighborhood Hits	29
SwissProt Accessions	P70275, O09078, O09079	Gene names	Sema3e, Semah, Semh
Domain Architecture
Description	Semaphorin-3E precursor (Semaphorin H) (Sema H).

SEM3F_MOUSE
θ value	2.36792 (rank : 2103)	NC score	0.012673 (rank : 2391)
Query Neighborhood Hits	2923	Target Neighborhood Hits	86	Shared Neighborhood Hits	41
SwissProt Accessions	O88632, O88633	Gene names	Sema3f
Domain Architecture
Description	Semaphorin-3F precursor (Semaphorin IV) (Sema IV).

SEPT8_HUMAN
θ value	2.36792 (rank : 2104)	NC score	0.012086 (rank : 2411)
Query Neighborhood Hits	2923	Target Neighborhood Hits	290	Shared Neighborhood Hits	149
SwissProt Accessions	Q92599, Q8IX36, Q8IX37, Q9BVB3	Gene names	SEPT8, KIAA0202
Domain Architecture
Description	Septin-8.

SETD8_HUMAN
θ value	2.36792 (rank : 2105)	NC score	0.014922 (rank : 2324)
Query Neighborhood Hits	2923	Target Neighborhood Hits	114	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NQR1, Q86W83, Q8TD09	Gene names	SETD8, PRSET7, SET07, SET8
Domain Architecture
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8) (PR/SET domain-containing protein 07) (PR/SET07) (PR-Set7).

SORC2_HUMAN
θ value	2.36792 (rank : 2106)	NC score	0.011413 (rank : 2429)
Query Neighborhood Hits	2923	Target Neighborhood Hits	66	Shared Neighborhood Hits	26
SwissProt Accessions	Q96PQ0, Q9P2L7	Gene names	SORCS2, KIAA1329
Domain Architecture
Description	VPS10 domain-containing receptor SorCS2 precursor.

SYNP2_HUMAN
θ value	2.36792 (rank : 2107)	NC score	0.012175 (rank : 2409)
Query Neighborhood Hits	2923	Target Neighborhood Hits	323	Shared Neighborhood Hits	118
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

TAK1L_HUMAN
θ value	2.36792 (rank : 2108)	NC score	0.029156 (rank : 2022)
Query Neighborhood Hits	2923	Target Neighborhood Hits	141	Shared Neighborhood Hits	84
SwissProt Accessions	P57077	Gene names	TAK1L, C21orf7
Domain Architecture	No domain graphic available
Description	TAK1-like protein.

TERT_MOUSE
θ value	2.36792 (rank : 2109)	NC score	0.007243 (rank : 2558)
Query Neighborhood Hits	2923	Target Neighborhood Hits	50	Shared Neighborhood Hits	27
SwissProt Accessions	O70372, O35432, Q9JK99	Gene names	Tert
Domain Architecture	No domain graphic available
Description	Telomerase reverse transcriptase (EC 2.7.7.49) (Telomerase catalytic subunit).

TM1L1_MOUSE
θ value	2.36792 (rank : 2110)	NC score	0.002864 (rank : 2732)
Query Neighborhood Hits	2923	Target Neighborhood Hits	43	Shared Neighborhood Hits	16
SwissProt Accessions	Q923U0, Q99KE0, Q9D6Y5	Gene names	Tom1l1, Srcasm
Domain Architecture
Description	TOM1-like 1 protein (Target of myb-like 1 protein) (Src-activating and signaling molecule protein).

TNNT3_MOUSE
θ value	2.36792 (rank : 2111)	NC score	0.035421 (rank : 1922)
Query Neighborhood Hits	2923	Target Neighborhood Hits	317	Shared Neighborhood Hits	188
SwissProt Accessions	Q9QZ47, O35575, O35576, O35577, O35578, O35579, O35580, O35581, O35582, O35583, O35584, O35585, P97456, Q99L89, Q9QZ46	Gene names	Tnnt3
Domain Architecture	No domain graphic available
Description	Troponin T, fast skeletal muscle (TnTf) (Fast skeletal muscle troponin T) (fTnT).

TPM4_HUMAN
θ value	2.36792 (rank : 2112)	NC score	0.042563 (rank : 1803)
Query Neighborhood Hits	2923	Target Neighborhood Hits	525	Shared Neighborhood Hits	240
SwissProt Accessions	P67936, P07226, Q15659, Q9BU85, Q9H8Q3	Gene names	TPM4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4) (TM30p1).

TRUB1_MOUSE
θ value	2.36792 (rank : 2113)	NC score	0.005679 (rank : 2608)
Query Neighborhood Hits	2923	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C0D0, Q5EBH7, Q9D331	Gene names	Trub1
Domain Architecture	No domain graphic available
Description	Probable tRNA pseudouridine synthase 1 (EC 5.4.99.-).

TTC15_MOUSE
θ value	2.36792 (rank : 2114)	NC score	0.009841 (rank : 2477)
Query Neighborhood Hits	2923	Target Neighborhood Hits	113	Shared Neighborhood Hits	32
SwissProt Accessions	Q8K2L8, Q8BX27	Gene names	Ttc15
Domain Architecture
Description	Tetratricopeptide repeat protein 15 (TPR repeat protein 15).

UB7I1_MOUSE
θ value	2.36792 (rank : 2115)	NC score	0.008138 (rank : 2532)
Query Neighborhood Hits	2923	Target Neighborhood Hits	206	Shared Neighborhood Hits	58
SwissProt Accessions	P58283, Q3U493, Q3UE56, Q3UGM3, Q68FN0, Q6P1H8, Q6PWY5, Q8BN27, Q8C1U3	Gene names	Ubce7ip1, Triad3, Uip83, Zin
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (UbcM4-interacting protein 83) (Triad domain- containing protein 3).

UBF1_HUMAN
θ value	2.36792 (rank : 2116)	NC score	0.015431 (rank : 2306)
Query Neighborhood Hits	2923	Target Neighborhood Hits	415	Shared Neighborhood Hits	159
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

UBP10_HUMAN
θ value	2.36792 (rank : 2117)	NC score	0.002612 (rank : 2737)
Query Neighborhood Hits	2923	Target Neighborhood Hits	153	Shared Neighborhood Hits	38
SwissProt Accessions	Q14694, Q9BWG7, Q9NSL7	Gene names	USP10, KIAA0190
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

UBPW_MOUSE
θ value	2.36792 (rank : 2118)	NC score	-0.005700 (rank : 2989)
Query Neighborhood Hits	2923	Target Neighborhood Hits	89	Shared Neighborhood Hits	10
SwissProt Accessions	Q61068	Gene names	Dub1, Dub-1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase DUB-1 (EC 3.1.2.15) (Ubiquitin thioesterase DUB-1) (Ubiquitin-specific-processing protease DUB-1) (Deubiquitinating enzyme 1).

UCRI_MOUSE
θ value	2.36792 (rank : 2119)	NC score	0.006804 (rank : 2578)
Query Neighborhood Hits	2923	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CR68	Gene names	Uqcrfs1
Domain Architecture	No domain graphic available
Description	Ubiquinol-cytochrome c reductase iron-sulfur subunit, mitochondrial precursor (EC 1.10.2.2) (Rieske iron-sulfur protein) (RISP).

VPP4_MOUSE
θ value	2.36792 (rank : 2120)	NC score	0.002763 (rank : 2734)
Query Neighborhood Hits	2923	Target Neighborhood Hits	35	Shared Neighborhood Hits	14
SwissProt Accessions	Q920R6, Q8CJ79, Q920B5	Gene names	Atp6v0a4, Atp6n1b
Domain Architecture
Description	Vacuolar proton translocating ATPase 116 kDa subunit a isoform 4 (V- ATPase 116 kDa isoform a4) (Vacuolar proton translocating ATPase 116 kDa subunit a kidney isoform).

ZBT39_HUMAN
θ value	2.36792 (rank : 2121)	NC score	-0.030609 (rank : 3127)
Query Neighborhood Hits	2923	Target Neighborhood Hits	805	Shared Neighborhood Hits	62
SwissProt Accessions	O15060	Gene names	ZBTB39, KIAA0352
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 39.

ZN185_MOUSE
θ value	2.36792 (rank : 2122)	NC score	0.009261 (rank : 2501)
Query Neighborhood Hits	2923	Target Neighborhood Hits	89	Shared Neighborhood Hits	28
SwissProt Accessions	Q62394	Gene names	Znf185, Zfp185
Domain Architecture
Description	Zinc finger protein 185 (LIM-domain protein Zfp185) (P1-A).

ZN509_MOUSE
θ value	2.36792 (rank : 2123)	NC score	-0.029293 (rank : 3110)
Query Neighborhood Hits	2923	Target Neighborhood Hits	990	Shared Neighborhood Hits	147
SwissProt Accessions	Q8BXX2, Q8CID4, Q8K2Z6	Gene names	Znf509, Zfp509
Domain Architecture	No domain graphic available
Description	Zinc finger protein 509.

ABC8A_MOUSE
θ value	3.0926 (rank : 2124)	NC score	-0.006988 (rank : 3007)
Query Neighborhood Hits	2923	Target Neighborhood Hits	115	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K442, Q6PAV3, Q8C0A9, Q8R0R4	Gene names	Abca8a
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 8-A.

ABCF1_HUMAN
θ value	3.0926 (rank : 2125)	NC score	0.010821 (rank : 2448)
Query Neighborhood Hits	2923	Target Neighborhood Hits	343	Shared Neighborhood Hits	143
SwissProt Accessions	Q8NE71, O14897, Q69YP6	Gene names	ABCF1, ABC50
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50) (TNF-alpha-stimulated ABC protein).

AMRP_HUMAN
θ value	3.0926 (rank : 2126)	NC score	0.014119 (rank : 2355)
Query Neighborhood Hits	2923	Target Neighborhood Hits	126	Shared Neighborhood Hits	62
SwissProt Accessions	P30533	Gene names	LRPAP1, A2MRAP
Domain Architecture
Description	Alpha-2-macroglobulin receptor-associated protein precursor (Alpha-2- MRAP) (Low density lipoprotein receptor-related protein-associated protein 1) (RAP).

ANTR1_MOUSE
θ value	3.0926 (rank : 2127)	NC score	0.020383 (rank : 2196)
Query Neighborhood Hits	2923	Target Neighborhood Hits	143	Shared Neighborhood Hits	89
SwissProt Accessions	Q9CZ52	Gene names	Antxr1, Atr, Tem8
Domain Architecture
Description	Anthrax toxin receptor 1 precursor (Tumor endothelial marker 8).

BACH2_HUMAN
θ value	3.0926 (rank : 2128)	NC score	-0.009082 (rank : 3049)
Query Neighborhood Hits	2923	Target Neighborhood Hits	234	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BYV9, Q59H70, Q5T793, Q9NTS5	Gene names	BACH2
Domain Architecture
Description	Transcription regulator protein BACH2 (BTB and CNC homolog 2).

BAIP3_MOUSE
θ value	3.0926 (rank : 2129)	NC score	0.015541 (rank : 2302)
Query Neighborhood Hits	2923	Target Neighborhood Hits	112	Shared Neighborhood Hits	21
SwissProt Accessions	Q80TT2, Q6RUT4	Gene names	Baiap3, Gm937, Kiaa0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

BAZ2A_MOUSE
θ value	3.0926 (rank : 2130)	NC score	0.026835 (rank : 2067)
Query Neighborhood Hits	2923	Target Neighborhood Hits	744	Shared Neighborhood Hits	305
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

BICD1_HUMAN
θ value	3.0926 (rank : 2131)	NC score	0.048920 (rank : 1718)
Query Neighborhood Hits	2923	Target Neighborhood Hits	844	Shared Neighborhood Hits	350
SwissProt Accessions	Q96G01, O43892, O43893	Gene names	BICD1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

BICD1_MOUSE
θ value	3.0926 (rank : 2132)	NC score	0.048442 (rank : 1729)
Query Neighborhood Hits	2923	Target Neighborhood Hits	837	Shared Neighborhood Hits	341
SwissProt Accessions	Q8BR07, O55206, Q8BQ18, Q8BRR8, Q8C4D3, Q8CAK6, Q8R2J4, Q8R2J5, Q8R2J6, Q91YP7	Gene names	Bicd1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

BNC1_HUMAN
θ value	3.0926 (rank : 2133)	NC score	-0.005535 (rank : 2985)
Query Neighborhood Hits	2923	Target Neighborhood Hits	460	Shared Neighborhood Hits	50
SwissProt Accessions	Q01954, Q15840	Gene names	BNC1, BNC
Domain Architecture	No domain graphic available
Description	Zinc finger protein basonuclin-1.

BTBDC_HUMAN
θ value	3.0926 (rank : 2134)	NC score	0.025550 (rank : 2100)
Query Neighborhood Hits	2923	Target Neighborhood Hits	248	Shared Neighborhood Hits	84
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

BUB1_MOUSE
θ value	3.0926 (rank : 2135)	NC score	0.486462 (rank : 862)
Query Neighborhood Hits	2923	Target Neighborhood Hits	583	Shared Neighborhood Hits	548
SwissProt Accessions	O08901, O09007	Gene names	Bub1
Domain Architecture
Description	Mitotic checkpoint serine/threonine-protein kinase BUB1 (EC 2.7.11.1) (MBUB1) (BUB1A).

CACB2_HUMAN
θ value	3.0926 (rank : 2136)	NC score	0.004926 (rank : 2640)
Query Neighborhood Hits	2923	Target Neighborhood Hits	99	Shared Neighborhood Hits	29
SwissProt Accessions	Q08289, O00304, Q8WX81, Q96NZ3, Q96NZ4, Q96NZ5, Q9BWU2, Q9HD32, Q9Y340, Q9Y341	Gene names	CACNB2, CACNLB2, MYSB
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2) (Lambert-Eaton myasthenic syndrome antigen B) (MYSB).

CACB2_MOUSE
θ value	3.0926 (rank : 2137)	NC score	0.003946 (rank : 2678)
Query Neighborhood Hits	2923	Target Neighborhood Hits	94	Shared Neighborhood Hits	20
SwissProt Accessions	Q8CC27, Q8C5J5, Q9CTQ6	Gene names	Cacnb2, Cacnlb2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2).

CAD10_HUMAN
θ value	3.0926 (rank : 2138)	NC score	-0.010209 (rank : 3055)
Query Neighborhood Hits	2923	Target Neighborhood Hits	162	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y6N8, Q9ULB3	Gene names	CDH10
Domain Architecture
Description	Cadherin-10 precursor (T2-cadherin).

CASP5_HUMAN
θ value	3.0926 (rank : 2139)	NC score	-0.000045 (rank : 2840)
Query Neighborhood Hits	2923	Target Neighborhood Hits	28	Shared Neighborhood Hits	5
SwissProt Accessions	P51878	Gene names	CASP5, ICH3
Domain Architecture
Description	Caspase-5 precursor (EC 3.4.22.-) (CASP-5) (ICH-3 protease) (TY protease) (ICE(rel)-III) [Contains: Caspase-5 subunit p20; Caspase-5 subunit p10].

CBP_HUMAN
θ value	3.0926 (rank : 2140)	NC score	0.045610 (rank : 1756)
Query Neighborhood Hits	2923	Target Neighborhood Hits	941	Shared Neighborhood Hits	366
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CCD27_MOUSE
θ value	3.0926 (rank : 2141)	NC score	0.049906 (rank : 1709)
Query Neighborhood Hits	2923	Target Neighborhood Hits	461	Shared Neighborhood Hits	239
SwissProt Accessions	Q3V036	Gene names	Ccdc27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

CCD47_HUMAN
θ value	3.0926 (rank : 2142)	NC score	0.013995 (rank : 2360)
Query Neighborhood Hits	2923	Target Neighborhood Hits	119	Shared Neighborhood Hits	48
SwissProt Accessions	Q96A33, Q96D00, Q96JZ7, Q9H3E4, Q9NRG3	Gene names	CCDC47
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor.

CCNB3_MOUSE
θ value	3.0926 (rank : 2143)	NC score	0.014000 (rank : 2359)
Query Neighborhood Hits	2923	Target Neighborhood Hits	211	Shared Neighborhood Hits	100
SwissProt Accessions	Q810T2, Q810T3, Q8VDC8	Gene names	Ccnb3, Cycb3
Domain Architecture
Description	G2/mitotic-specific cyclin-B3.

CD2_HUMAN
θ value	3.0926 (rank : 2144)	NC score	0.034252 (rank : 1946)
Query Neighborhood Hits	2923	Target Neighborhood Hits	504	Shared Neighborhood Hits	181
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

CD86_HUMAN
θ value	3.0926 (rank : 2145)	NC score	0.058993 (rank : 1468)
Query Neighborhood Hits	2923	Target Neighborhood Hits	85	Shared Neighborhood Hits	69
SwissProt Accessions	P42081, Q13655, Q7M4L5	Gene names	CD86, CD28LG2
Domain Architecture
Description	T-lymphocyte activation antigen CD86 precursor (Activation B7-2 antigen) (CTLA-4 counter-receptor B7.2) (B70) (FUN-1) (BU63).

CF142_HUMAN
θ value	3.0926 (rank : 2146)	NC score	0.006866 (rank : 2576)
Query Neighborhood Hits	2923	Target Neighborhood Hits	25	Shared Neighborhood Hits	11
SwissProt Accessions	Q5VWP3, Q96H08, Q96NF7	Gene names	C6orf142
Domain Architecture	No domain graphic available
Description	Protein C6orf142.

CI078_HUMAN
θ value	3.0926 (rank : 2147)	NC score	0.013043 (rank : 2383)
Query Neighborhood Hits	2923	Target Neighborhood Hits	66	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NZ63, Q8WVU6, Q9NT39	Gene names	C9orf78
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf78 (Hepatocellular carcinoma-associated antigen 59).

CPNE3_HUMAN
θ value	3.0926 (rank : 2148)	NC score	0.004917 (rank : 2642)
Query Neighborhood Hits	2923	Target Neighborhood Hits	90	Shared Neighborhood Hits	14
SwissProt Accessions	O75131, Q8IYA1	Gene names	CPNE3, CPN3, KIAA0636
Domain Architecture
Description	Copine-3 (Copine III).

CR034_MOUSE
θ value	3.0926 (rank : 2149)	NC score	0.050602 (rank : 1690)
Query Neighborhood Hits	2923	Target Neighborhood Hits	643	Shared Neighborhood Hits	289
SwissProt Accessions	Q8CDV0	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34 homolog.

CSPG3_HUMAN
θ value	3.0926 (rank : 2150)	NC score	0.017754 (rank : 2243)
Query Neighborhood Hits	2923	Target Neighborhood Hits	676	Shared Neighborhood Hits	180
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

DC1L2_MOUSE
θ value	3.0926 (rank : 2151)	NC score	0.008865 (rank : 2510)
Query Neighborhood Hits	2923	Target Neighborhood Hits	173	Shared Neighborhood Hits	48
SwissProt Accessions	Q6PDL0	Gene names	Dync1li2, Dncli2, Dnclic2
Domain Architecture	No domain graphic available
Description	Cytoplasmic dynein 1 light intermediate chain 2 (Dynein light intermediate chain 2, cytosolic).

DDX10_HUMAN
θ value	3.0926 (rank : 2152)	NC score	-0.005450 (rank : 2982)
Query Neighborhood Hits	2923	Target Neighborhood Hits	210	Shared Neighborhood Hits	73
SwissProt Accessions	Q13206, Q5BJD8	Gene names	DDX10
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DHX15_HUMAN
θ value	3.0926 (rank : 2153)	NC score	-0.000858 (rank : 2873)
Query Neighborhood Hits	2923	Target Neighborhood Hits	50	Shared Neighborhood Hits	18
SwissProt Accessions	O43143, Q9NQT7	Gene names	DHX15, DBP1, DDX15
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 (EC 3.6.1.-) (DEAH box protein 15) (ATP-dependent RNA helicase #46).

DHX15_MOUSE
θ value	3.0926 (rank : 2154)	NC score	-0.000803 (rank : 2871)
Query Neighborhood Hits	2923	Target Neighborhood Hits	52	Shared Neighborhood Hits	19
SwissProt Accessions	O35286, Q99L91	Gene names	Dhx15, Ddx15, Deah9
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 (EC 3.6.1.-) (DEAH box protein 15).

DLGP2_MOUSE
θ value	3.0926 (rank : 2155)	NC score	0.002322 (rank : 2752)
Query Neighborhood Hits	2923	Target Neighborhood Hits	49	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BJ42, Q6XBF3	Gene names	Dlgap2, Dap2
Domain Architecture	No domain graphic available
Description	Disks large-associated protein 2 (DAP-2) (SAP90/PSD-95-associated protein 2) (SAPAP2) (PSD-95/SAP90-binding protein 2).

DOCK3_HUMAN
θ value	3.0926 (rank : 2156)	NC score	0.002539 (rank : 2743)
Query Neighborhood Hits	2923	Target Neighborhood Hits	87	Shared Neighborhood Hits	32
SwissProt Accessions	Q8IZD9, O15017	Gene names	DOCK3, KIAA0299, MOCA
Domain Architecture
Description	Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP protein).

DYN1_HUMAN
θ value	3.0926 (rank : 2157)	NC score	0.012933 (rank : 2387)
Query Neighborhood Hits	2923	Target Neighborhood Hits	216	Shared Neighborhood Hits	99
SwissProt Accessions	Q05193	Gene names	DNM1, DNM
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

DYN1_MOUSE
θ value	3.0926 (rank : 2158)	NC score	0.008651 (rank : 2517)
Query Neighborhood Hits	2923	Target Neighborhood Hits	168	Shared Neighborhood Hits	72
SwissProt Accessions	P39053, Q61358, Q61359, Q61360, Q8JZZ4, Q9CSY7, Q9QXX1	Gene names	Dnm1, Dnm
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

DZIP3_HUMAN
θ value	3.0926 (rank : 2159)	NC score	0.016324 (rank : 2283)
Query Neighborhood Hits	2923	Target Neighborhood Hits	399	Shared Neighborhood Hits	159
SwissProt Accessions	Q86Y13, O75162, Q6P3R9, Q6PH82, Q86Y14, Q86Y15, Q86Y16, Q8IWI0, Q96RS9	Gene names	DZIP3, KIAA0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3) (RNA-binding ubiquitin ligase of 138 kDa) (hRUL138).

EGFL9_HUMAN
θ value	3.0926 (rank : 2160)	NC score	0.026401 (rank : 2078)
Query Neighborhood Hits	2923	Target Neighborhood Hits	365	Shared Neighborhood Hits	62
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

EGFL9_MOUSE
θ value	3.0926 (rank : 2161)	NC score	0.025878 (rank : 2090)
Query Neighborhood Hits	2923	Target Neighborhood Hits	379	Shared Neighborhood Hits	65
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

ELK4_MOUSE
θ value	3.0926 (rank : 2162)	NC score	0.002570 (rank : 2740)
Query Neighborhood Hits	2923	Target Neighborhood Hits	107	Shared Neighborhood Hits	38
SwissProt Accessions	P41158	Gene names	Elk4, Sap1
Domain Architecture
Description	ETS domain-containing protein Elk-4 (Serum response factor accessory protein 1) (SAP-1).

ENP6_HUMAN
θ value	3.0926 (rank : 2163)	NC score	0.001021 (rank : 2800)
Query Neighborhood Hits	2923	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	O75354, Q7Z5B5, Q8TAS7, Q9UJD1	Gene names	ENTPD6, CD39L2
Domain Architecture
Description	Ectonucleoside triphosphate diphosphohydrolase 6 (EC 3.6.1.6) (NTPDase 6) (CD39 antigen-like 2).

EPC1_MOUSE
θ value	3.0926 (rank : 2164)	NC score	0.005127 (rank : 2629)
Query Neighborhood Hits	2923	Target Neighborhood Hits	47	Shared Neighborhood Hits	20
SwissProt Accessions	Q8C9X6, Q9Z299	Gene names	Epc1
Domain Architecture	No domain graphic available
Description	Enhancer of polycomb homolog 1.

ESCO1_MOUSE
θ value	3.0926 (rank : 2165)	NC score	0.016432 (rank : 2280)
Query Neighborhood Hits	2923	Target Neighborhood Hits	87	Shared Neighborhood Hits	54
SwissProt Accessions	Q69Z69, Q8BQI2, Q8BR47, Q922F5	Gene names	Esco1, Kiaa1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1).

FA13C_HUMAN
θ value	3.0926 (rank : 2166)	NC score	0.013227 (rank : 2379)
Query Neighborhood Hits	2923	Target Neighborhood Hits	94	Shared Neighborhood Hits	51
SwissProt Accessions	Q8NE31, Q99787	Gene names	FAM13C1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

FA8_HUMAN
θ value	3.0926 (rank : 2167)	NC score	0.003629 (rank : 2701)
Query Neighborhood Hits	2923	Target Neighborhood Hits	112	Shared Neighborhood Hits	31
SwissProt Accessions	P00451	Gene names	F8, F8C
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component) (Antihemophilic factor) (AHF) [Contains: Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIII B chain; Factor VIIIa light chain].

FGD6_HUMAN
θ value	3.0926 (rank : 2168)	NC score	0.005185 (rank : 2623)
Query Neighborhood Hits	2923	Target Neighborhood Hits	237	Shared Neighborhood Hits	55
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

FLRT1_HUMAN
θ value	3.0926 (rank : 2169)	NC score	0.039788 (rank : 1847)
Query Neighborhood Hits	2923	Target Neighborhood Hits	286	Shared Neighborhood Hits	77
SwissProt Accessions	Q9NZU1	Gene names	FLRT1
Domain Architecture
Description	Leucine-rich repeat transmembrane protein FLRT1 precursor (Fibronectin-like domain-containing leucine-rich transmembrane protein 1).

FOG2_HUMAN
θ value	3.0926 (rank : 2170)	NC score	-0.023012 (rank : 3087)
Query Neighborhood Hits	2923	Target Neighborhood Hits	731	Shared Neighborhood Hits	70
SwissProt Accessions	Q8WW38, Q9NPL7, Q9NPS4, Q9UNI5	Gene names	ZFPM2, FOG2
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM2 (Zinc finger protein multitype 2) (Friend of GATA protein 2) (FOG-2) (hFOG-2).

FOG2_MOUSE
θ value	3.0926 (rank : 2171)	NC score	-0.022744 (rank : 3086)
Query Neighborhood Hits	2923	Target Neighborhood Hits	714	Shared Neighborhood Hits	68
SwissProt Accessions	Q8CCH7, Q9Z0F2	Gene names	Zfpm2, Fog2
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM2 (Zinc finger protein multitype 2) (Friend of GATA protein 2) (Friend of GATA-2) (FOG-2) (mFOG-2).

GA45B_MOUSE
θ value	3.0926 (rank : 2172)	NC score	0.002220 (rank : 2756)
Query Neighborhood Hits	2923	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	P22339, Q3U342, Q9R106	Gene names	Gadd45b, Myd118
Domain Architecture
Description	Growth arrest and DNA-damage-inducible protein GADD45 beta (Negative growth-regulatory protein MyD118) (Myeloid differentiation primary response protein MyD118).

GABPA_HUMAN
θ value	3.0926 (rank : 2173)	NC score	-0.002800 (rank : 2930)
Query Neighborhood Hits	2923	Target Neighborhood Hits	55	Shared Neighborhood Hits	9
SwissProt Accessions	Q06546, Q12939	Gene names	GABPA, E4TF1A
Domain Architecture
Description	GA-binding protein alpha chain (GABP-subunit alpha) (Transcription factor E4TF1-60) (Nuclear respiratory factor 2 subunit alpha).

HXA3_HUMAN
θ value	3.0926 (rank : 2174)	NC score	-0.008374 (rank : 3036)
Query Neighborhood Hits	2923	Target Neighborhood Hits	535	Shared Neighborhood Hits	125
SwissProt Accessions	O43365	Gene names	HOXA3, HOX1E
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1E).

IL12B_HUMAN
θ value	3.0926 (rank : 2175)	NC score	0.036555 (rank : 1899)
Query Neighborhood Hits	2923	Target Neighborhood Hits	51	Shared Neighborhood Hits	40
SwissProt Accessions	P29460	Gene names	IL12B, NKSF2
Domain Architecture
Description	Interleukin-12 beta chain precursor (IL-12B) (IL-12 p40) (Cytotoxic lymphocyte maturation factor 40 kDa subunit) (CLMF p40) (NK cell stimulatory factor chain 2) (NKSF2).

INGR2_HUMAN
θ value	3.0926 (rank : 2176)	NC score	0.015645 (rank : 2297)
Query Neighborhood Hits	2923	Target Neighborhood Hits	22	Shared Neighborhood Hits	13
SwissProt Accessions	P38484, Q9BTL5	Gene names	IFNGR2, IFNGT1
Domain Architecture
Description	Interferon-gamma receptor beta chain precursor (Interferon-gamma receptor accessory factor 1) (AF-1) (Interferon-gamma transducer 1).

JAML1_HUMAN
θ value	3.0926 (rank : 2177)	NC score	0.088908 (rank : 1236)
Query Neighborhood Hits	2923	Target Neighborhood Hits	108	Shared Neighborhood Hits	90
SwissProt Accessions	Q86YT9, Q5DTC6, Q7Z499, Q8N9I7, Q8NF70	Gene names	AMICA1, JAML
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule-like precursor (Dendritic cell-specific protein CREA7-1) (Adhesion molecule interacting with CXADR antigen 1).

K1683_HUMAN
θ value	3.0926 (rank : 2178)	NC score	0.040418 (rank : 1838)
Query Neighborhood Hits	2923	Target Neighborhood Hits	240	Shared Neighborhood Hits	111
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

KI21A_MOUSE
θ value	3.0926 (rank : 2179)	NC score	0.027268 (rank : 2059)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1317	Shared Neighborhood Hits	463
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

KIFC1_HUMAN
θ value	3.0926 (rank : 2180)	NC score	0.026238 (rank : 2083)
Query Neighborhood Hits	2923	Target Neighborhood Hits	545	Shared Neighborhood Hits	262
SwissProt Accessions	Q9BW19, O60887, Q14834, Q9UQP7	Gene names	KIFC1, HSET, KNSL2
Domain Architecture
Description	Kinesin-like protein KIFC1 (Kinesin-like protein 2) (Kinesin-related protein HSET).

KV1A_HUMAN
θ value	3.0926 (rank : 2181)	NC score	-0.001330 (rank : 2893)
Query Neighborhood Hits	2923	Target Neighborhood Hits	203	Shared Neighborhood Hits	69
SwissProt Accessions	P01593	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-I region AG.

KV1Q_HUMAN
θ value	3.0926 (rank : 2182)	NC score	0.000924 (rank : 2808)
Query Neighborhood Hits	2923	Target Neighborhood Hits	197	Shared Neighborhood Hits	78
SwissProt Accessions	P01609	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-I region Scw.

KV5N_MOUSE
θ value	3.0926 (rank : 2183)	NC score	-0.002626 (rank : 2925)
Query Neighborhood Hits	2923	Target Neighborhood Hits	206	Shared Neighborhood Hits	70
SwissProt Accessions	P01647	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-V region HP 124E1.

LAP4_MOUSE
θ value	3.0926 (rank : 2184)	NC score	0.021025 (rank : 2184)
Query Neighborhood Hits	2923	Target Neighborhood Hits	590	Shared Neighborhood Hits	157
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

LCP2_MOUSE
θ value	3.0926 (rank : 2185)	NC score	0.038887 (rank : 1859)
Query Neighborhood Hits	2923	Target Neighborhood Hits	177	Shared Neighborhood Hits	80
SwissProt Accessions	Q60787	Gene names	Lcp2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

LHX4_MOUSE
θ value	3.0926 (rank : 2186)	NC score	-0.013611 (rank : 3070)
Query Neighborhood Hits	2923	Target Neighborhood Hits	457	Shared Neighborhood Hits	30
SwissProt Accessions	P53776, O08916, Q9R280	Gene names	Lhx4, Gsh-4, Gsh4
Domain Architecture
Description	LIM/homeobox protein Lhx4.

LRP11_MOUSE
θ value	3.0926 (rank : 2187)	NC score	0.011743 (rank : 2418)
Query Neighborhood Hits	2923	Target Neighborhood Hits	81	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CB67, Q8C7Y7	Gene names	Lrp11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.

LV4D_HUMAN
θ value	3.0926 (rank : 2188)	NC score	0.000439 (rank : 2825)
Query Neighborhood Hits	2923	Target Neighborhood Hits	199	Shared Neighborhood Hits	69
SwissProt Accessions	P01718	Gene names
Domain Architecture	No domain graphic available
Description	Ig lambda chain V-IV region Kern.

LYRM3_HUMAN
θ value	3.0926 (rank : 2189)	NC score	0.007983 (rank : 2541)
Query Neighborhood Hits	2923	Target Neighborhood Hits	3	Shared Neighborhood Hits	2
SwissProt Accessions	Q5U5X0, Q86Y68	Gene names	LYRM3, C5orf31
Domain Architecture	No domain graphic available
Description	LYR motif-containing protein 3.

MMP17_MOUSE
θ value	3.0926 (rank : 2190)	NC score	-0.006265 (rank : 2998)
Query Neighborhood Hits	2923	Target Neighborhood Hits	60	Shared Neighborhood Hits	6
SwissProt Accessions	Q9R0S3	Gene names	Mmp17, Mt4mmp
Domain Architecture
Description	Matrix metalloproteinase-17 precursor (EC 3.4.24.-) (MMP-17) (Membrane-type matrix metalloproteinase 4) (MT-MMP 4) (Membrane-type-4 matrix metalloproteinase) (MT4-MMP).

MNT_MOUSE
θ value	3.0926 (rank : 2191)	NC score	0.039152 (rank : 1851)
Query Neighborhood Hits	2923	Target Neighborhood Hits	432	Shared Neighborhood Hits	200
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MRP5_HUMAN
θ value	3.0926 (rank : 2192)	NC score	-0.007895 (rank : 3030)
Query Neighborhood Hits	2923	Target Neighborhood Hits	110	Shared Neighborhood Hits	11
SwissProt Accessions	O15440, O14517, Q9UN85, Q9UNP5, Q9UQC3	Gene names	ABCC5, MRP5
Domain Architecture
Description	Multidrug resistance-associated protein 5 (ATP-binding cassette sub- family C member 5) (Multi-specific organic anion transporter-C) (MOAT- C) (pABC11) (SMRP).

MYH10_HUMAN
θ value	3.0926 (rank : 2193)	NC score	0.054446 (rank : 1591)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1620	Shared Neighborhood Hits	525
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYRIP_MOUSE
θ value	3.0926 (rank : 2194)	NC score	0.012058 (rank : 2413)
Query Neighborhood Hits	2923	Target Neighborhood Hits	207	Shared Neighborhood Hits	86
SwissProt Accessions	Q8K3I4, Q8CFC0, Q8K4H5	Gene names	Myrip, Slac2c
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

MYST4_MOUSE
θ value	3.0926 (rank : 2195)	NC score	0.007541 (rank : 2553)
Query Neighborhood Hits	2923	Target Neighborhood Hits	416	Shared Neighborhood Hits	160
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

NCOA6_MOUSE
θ value	3.0926 (rank : 2196)	NC score	0.050416 (rank : 1696)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1076	Shared Neighborhood Hits	371
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

NCOR2_HUMAN
θ value	3.0926 (rank : 2197)	NC score	0.063398 (rank : 1366)
Query Neighborhood Hits	2923	Target Neighborhood Hits	870	Shared Neighborhood Hits	431
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

NOG2_HUMAN
θ value	3.0926 (rank : 2198)	NC score	0.012006 (rank : 2414)
Query Neighborhood Hits	2923	Target Neighborhood Hits	117	Shared Neighborhood Hits	67
SwissProt Accessions	Q13823, Q9BWN7	Gene names	GNL2, NGP1
Domain Architecture
Description	Nucleolar GTP-binding protein 2 (Autoantigen NGP-1).

NOG2_MOUSE
θ value	3.0926 (rank : 2199)	NC score	0.007808 (rank : 2545)
Query Neighborhood Hits	2923	Target Neighborhood Hits	71	Shared Neighborhood Hits	37
SwissProt Accessions	Q99LH1, Q8BIF8	Gene names	Gnl2
Domain Architecture	No domain graphic available
Description	Nucleolar GTP-binding protein 2.

NUCL_HUMAN
θ value	3.0926 (rank : 2200)	NC score	0.002982 (rank : 2727)
Query Neighborhood Hits	2923	Target Neighborhood Hits	415	Shared Neighborhood Hits	99
SwissProt Accessions	P19338, Q53SK1, Q8NB06	Gene names	NCL
Domain Architecture
Description	Nucleolin (Protein C23).

NUCL_MOUSE
θ value	3.0926 (rank : 2201)	NC score	0.002341 (rank : 2751)
Query Neighborhood Hits	2923	Target Neighborhood Hits	425	Shared Neighborhood Hits	103
SwissProt Accessions	P09405, Q548M9, Q61991, Q99K50	Gene names	Ncl, Nuc
Domain Architecture
Description	Nucleolin (Protein C23).

NUP88_MOUSE
θ value	3.0926 (rank : 2202)	NC score	0.028606 (rank : 2031)
Query Neighborhood Hits	2923	Target Neighborhood Hits	239	Shared Neighborhood Hits	141
SwissProt Accessions	Q8CEC0, Q80Z13, Q8K090	Gene names	Nup88
Domain Architecture	No domain graphic available
Description	Nuclear pore complex protein Nup88 (Nucleoporin Nup88) (88 kDa nuclear pore complex protein).

P2Y14_MOUSE
θ value	3.0926 (rank : 2203)	NC score	-0.024357 (rank : 3089)
Query Neighborhood Hits	2923	Target Neighborhood Hits	520	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ESG6	Gene names	P2ry14, Gpr105
Domain Architecture
Description	P2Y purinoceptor 14 (P2Y14) (UDP-glucose receptor) (G-protein coupled receptor 105).

PDZD2_HUMAN
θ value	3.0926 (rank : 2204)	NC score	0.022261 (rank : 2165)
Query Neighborhood Hits	2923	Target Neighborhood Hits	772	Shared Neighborhood Hits	235
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

PEPL_MOUSE
θ value	3.0926 (rank : 2205)	NC score	0.059998 (rank : 1440)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1105	Shared Neighborhood Hits	437
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

PER1_HUMAN
θ value	3.0926 (rank : 2206)	NC score	0.014473 (rank : 2343)
Query Neighborhood Hits	2923	Target Neighborhood Hits	215	Shared Neighborhood Hits	98
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

PGCB_HUMAN
θ value	3.0926 (rank : 2207)	NC score	0.012477 (rank : 2403)
Query Neighborhood Hits	2923	Target Neighborhood Hits	478	Shared Neighborhood Hits	142
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

PKCB1_HUMAN
θ value	3.0926 (rank : 2208)	NC score	0.026486 (rank : 2076)
Query Neighborhood Hits	2923	Target Neighborhood Hits	488	Shared Neighborhood Hits	205
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

PLVAP_HUMAN
θ value	3.0926 (rank : 2209)	NC score	0.042744 (rank : 1798)
Query Neighborhood Hits	2923	Target Neighborhood Hits	397	Shared Neighborhood Hits	226
SwissProt Accessions	Q9BX97, Q86VP0, Q8N8Y0, Q8ND68, Q8TER8, Q9BZD5	Gene names	PLVAP, FELS, PV1
Domain Architecture	No domain graphic available
Description	Plasmalemma vesicle-associated protein (Plasmalemma vesicle protein 1) (PV-1) (Fenestrated endothelial-linked structure protein).

PLXB1_HUMAN
θ value	3.0926 (rank : 2210)	NC score	0.004455 (rank : 2662)
Query Neighborhood Hits	2923	Target Neighborhood Hits	360	Shared Neighborhood Hits	128
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

PRPE_HUMAN
θ value	3.0926 (rank : 2211)	NC score	0.053525 (rank : 1628)
Query Neighborhood Hits	2923	Target Neighborhood Hits	44	Shared Neighborhood Hits	21
SwissProt Accessions	P02811	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide P-E (IB-9).

RABE1_HUMAN
θ value	3.0926 (rank : 2212)	NC score	0.057391 (rank : 1509)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1104	Shared Neighborhood Hits	421
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

RAD21_HUMAN
θ value	3.0926 (rank : 2213)	NC score	0.009589 (rank : 2485)
Query Neighborhood Hits	2923	Target Neighborhood Hits	46	Shared Neighborhood Hits	26
SwissProt Accessions	O60216, Q15001, Q99568	Gene names	RAD21, HR21, KIAA0078, NXP1
Domain Architecture
Description	Double-strand-break repair protein rad21 homolog (hHR21) (Nuclear matrix protein 1) (NXP-1) (SCC1 homolog).

RAD21_MOUSE
θ value	3.0926 (rank : 2214)	NC score	0.012990 (rank : 2385)
Query Neighborhood Hits	2923	Target Neighborhood Hits	59	Shared Neighborhood Hits	34
SwissProt Accessions	Q61550, P70219, Q91VB9, Q9DBU4	Gene names	Rad21, Hr21
Domain Architecture
Description	Double-strand-break repair protein rad21 homolog (Pokeweed agglutinin- binding protein 29) (PW29) (SCC1 homolog).

RBM28_MOUSE
θ value	3.0926 (rank : 2215)	NC score	-0.002385 (rank : 2917)
Query Neighborhood Hits	2923	Target Neighborhood Hits	368	Shared Neighborhood Hits	92
SwissProt Accessions	Q8CGC6, Q8BG25, Q8VEJ8, Q9CS22, Q9CSE6	Gene names	Rbm28
Domain Architecture	No domain graphic available
Description	RNA-binding protein 28 (RNA-binding motif protein 28).

RBPMS_MOUSE
θ value	3.0926 (rank : 2216)	NC score	0.004241 (rank : 2670)
Query Neighborhood Hits	2923	Target Neighborhood Hits	47	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WVB0	Gene names	Rbpms, Hermes
Domain Architecture
Description	RNA-binding protein with multiple splicing (RBP-MS) (HEart, RRM Expressed Sequence) (Hermes).

REC8L_HUMAN
θ value	3.0926 (rank : 2217)	NC score	0.019767 (rank : 2208)
Query Neighborhood Hits	2923	Target Neighborhood Hits	45	Shared Neighborhood Hits	27
SwissProt Accessions	O95072, Q8WUV8, Q9BTF2, Q9NVQ9	Gene names	REC8L1, REC8
Domain Architecture
Description	Meiotic recombination protein REC8-like 1 (Cohesin Rec8p).

RIF1_MOUSE
θ value	3.0926 (rank : 2218)	NC score	0.024900 (rank : 2109)
Query Neighborhood Hits	2923	Target Neighborhood Hits	315	Shared Neighborhood Hits	145
SwissProt Accessions	Q6PR54, Q6T8D9, Q7TPD8, Q8BTU2, Q8C408, Q9CS77	Gene names	Rif1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog) (mRif1).

S23IP_MOUSE
θ value	3.0926 (rank : 2219)	NC score	0.017309 (rank : 2253)
Query Neighborhood Hits	2923	Target Neighborhood Hits	363	Shared Neighborhood Hits	140
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

SCN4B_HUMAN
θ value	3.0926 (rank : 2220)	NC score	0.047864 (rank : 1733)
Query Neighborhood Hits	2923	Target Neighborhood Hits	68	Shared Neighborhood Hits	57
SwissProt Accessions	Q8IWT1, Q6PIG5	Gene names	SCN4B
Domain Architecture	No domain graphic available
Description	Sodium channel beta-4 subunit precursor.

SDPR_MOUSE
θ value	3.0926 (rank : 2221)	NC score	0.037494 (rank : 1882)
Query Neighborhood Hits	2923	Target Neighborhood Hits	485	Shared Neighborhood Hits	233
SwissProt Accessions	Q63918, Q3V1P6, Q78EC3, Q8CBT4	Gene names	Sdpr, Sdr
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein).

SMC3_HUMAN
θ value	3.0926 (rank : 2222)	NC score	0.054407 (rank : 1594)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1186	Shared Neighborhood Hits	437
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

SMC3_MOUSE
θ value	3.0926 (rank : 2223)	NC score	0.054667 (rank : 1587)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1187	Shared Neighborhood Hits	439
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

SMN_HUMAN
θ value	3.0926 (rank : 2224)	NC score	0.008349 (rank : 2526)
Query Neighborhood Hits	2923	Target Neighborhood Hits	39	Shared Neighborhood Hits	14
SwissProt Accessions	Q16637, Q13119, Q96J51	Gene names	SMN1, SMN, SMNT
Domain Architecture
Description	Survival motor neuron protein (Component of gems 1) (Gemin-1).

SYNE2_HUMAN
θ value	3.0926 (rank : 2225)	NC score	0.042118 (rank : 1811)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1323	Shared Neighborhood Hits	443
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

SYNP2_MOUSE
θ value	3.0926 (rank : 2226)	NC score	0.014813 (rank : 2328)
Query Neighborhood Hits	2923	Target Neighborhood Hits	252	Shared Neighborhood Hits	95
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

TAF6L_MOUSE
θ value	3.0926 (rank : 2227)	NC score	0.008597 (rank : 2520)
Query Neighborhood Hits	2923	Target Neighborhood Hits	146	Shared Neighborhood Hits	44
SwissProt Accessions	Q8R2K4, Q8C5T2	Gene names	Taf6l, Paf65a
Domain Architecture
Description	TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (PCAF-associated factor 65 alpha) (PAF65- alpha).

TRIM8_MOUSE
θ value	3.0926 (rank : 2228)	NC score	0.012596 (rank : 2393)
Query Neighborhood Hits	2923	Target Neighborhood Hits	674	Shared Neighborhood Hits	225
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRUB1_HUMAN
θ value	3.0926 (rank : 2229)	NC score	0.005229 (rank : 2622)
Query Neighborhood Hits	2923	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WWH5, Q53ES2	Gene names	TRUB1, PUS4
Domain Architecture	No domain graphic available
Description	Probable tRNA pseudouridine synthase 1 (EC 5.4.99.-).

TSH3_MOUSE
θ value	3.0926 (rank : 2230)	NC score	-0.002331 (rank : 2913)
Query Neighborhood Hits	2923	Target Neighborhood Hits	590	Shared Neighborhood Hits	95
SwissProt Accessions	Q8CGV9, Q5DTX4	Gene names	Tshz3, Kiaa1474, Tsh3, Zfp537, Znf537
Domain Architecture	No domain graphic available
Description	Teashirt homolog 3 (Zinc finger protein 537).

TXND3_MOUSE
θ value	3.0926 (rank : 2231)	NC score	0.002288 (rank : 2753)
Query Neighborhood Hits	2923	Target Neighborhood Hits	51	Shared Neighborhood Hits	13
SwissProt Accessions	Q715T0, Q80W74	Gene names	Txndc3, Sptrx2
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 3 (Spermatid-specific thioredoxin-2) (Sptrx-2).

U2AFM_HUMAN
θ value	3.0926 (rank : 2232)	NC score	0.035890 (rank : 1906)
Query Neighborhood Hits	2923	Target Neighborhood Hits	577	Shared Neighborhood Hits	273
SwissProt Accessions	Q15696	Gene names	ZRSR2, U2AF1-RS2, U2AF1L2, U2AF1RS2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2) (NY-REN-20 antigen).

UBP29_HUMAN
θ value	3.0926 (rank : 2233)	NC score	-0.003243 (rank : 2939)
Query Neighborhood Hits	2923	Target Neighborhood Hits	94	Shared Neighborhood Hits	12
SwissProt Accessions	Q9HBJ7	Gene names	USP29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

UROL1_HUMAN
θ value	3.0926 (rank : 2234)	NC score	0.010511 (rank : 2454)
Query Neighborhood Hits	2923	Target Neighborhood Hits	213	Shared Neighborhood Hits	43
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

VATA1_HUMAN
θ value	3.0926 (rank : 2235)	NC score	0.002138 (rank : 2759)
Query Neighborhood Hits	2923	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	P38606, Q96DY6, Q9UHY3	Gene names	ATP6V1A, ATP6A1, ATP6V1A1, VPP2
Domain Architecture
Description	Vacuolar ATP synthase catalytic subunit A, ubiquitous isoform (EC 3.6.3.14) (V-ATPase subunit A 1) (Vacuolar proton pump alpha subunit 1) (V-ATPase 69 kDa subunit 1) (Isoform VA68).

VATA1_MOUSE
θ value	3.0926 (rank : 2236)	NC score	0.002206 (rank : 2757)
Query Neighborhood Hits	2923	Target Neighborhood Hits	19	Shared Neighborhood Hits	5
SwissProt Accessions	P50516	Gene names	Atp6v1a, Atp6a1, Atp6a2, Atp6v1a1
Domain Architecture
Description	Vacuolar ATP synthase catalytic subunit A, ubiquitous isoform (EC 3.6.3.14) (V-ATPase subunit A 1) (Vacuolar proton pump alpha subunit 1) (V-ATPase 69 kDa subunit 1).

VINC_HUMAN
θ value	3.0926 (rank : 2237)	NC score	0.012579 (rank : 2396)
Query Neighborhood Hits	2923	Target Neighborhood Hits	145	Shared Neighborhood Hits	88
SwissProt Accessions	P18206, Q16450, Q5SWX2, Q7Z3B8, Q8IXU7	Gene names	VCL
Domain Architecture
Description	Vinculin (Metavinculin).

VINC_MOUSE
θ value	3.0926 (rank : 2238)	NC score	0.009463 (rank : 2492)
Query Neighborhood Hits	2923	Target Neighborhood Hits	135	Shared Neighborhood Hits	75
SwissProt Accessions	Q64727, Q8BP32, Q8BS46, Q922C5, Q922D9	Gene names	Vcl
Domain Architecture
Description	Vinculin (Metavinculin).

VPS25_HUMAN
θ value	3.0926 (rank : 2239)	NC score	0.006145 (rank : 2599)
Query Neighborhood Hits	2923	Target Neighborhood Hits	3	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BRG1	Gene names	VPS25, DERP9, EAP20
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 25 (hVps25) (ELL- associated protein of 20 kDa) (Dermal papilla-derived protein 9).

VRK2_MOUSE
θ value	3.0926 (rank : 2240)	NC score	0.383122 (rank : 956)
Query Neighborhood Hits	2923	Target Neighborhood Hits	586	Shared Neighborhood Hits	567
SwissProt Accessions	Q8BN21, Q5F1Z5, Q5SP88, Q8BPU8, Q8CJ46, Q91WS1, Q9CZF9	Gene names	Vrk2
Domain Architecture
Description	Serine/threonine-protein kinase VRK2 (EC 2.7.11.1) (Vaccinia-related kinase 2).

XKR6_HUMAN
θ value	3.0926 (rank : 2241)	NC score	-0.000096 (rank : 2842)
Query Neighborhood Hits	2923	Target Neighborhood Hits	43	Shared Neighborhood Hits	6
SwissProt Accessions	Q5GH73, Q8TBA0	Gene names	XKR6, C8orf21, C8orf7, XRG6
Domain Architecture	No domain graphic available
Description	XK-related protein 6.

ZF161_HUMAN
θ value	3.0926 (rank : 2242)	NC score	-0.031722 (rank : 3128)
Query Neighborhood Hits	2923	Target Neighborhood Hits	822	Shared Neighborhood Hits	66
SwissProt Accessions	O43829, O00403	Gene names	ZFP161, ZBTB14
Domain Architecture
Description	Zinc finger protein 161 homolog (Zfp-161) (Zinc finger protein 5) (hZF5) (Zinc finger and BTB domain-containing protein 14).

ZF161_MOUSE
θ value	3.0926 (rank : 2243)	NC score	-0.031736 (rank : 3129)
Query Neighborhood Hits	2923	Target Neighborhood Hits	821	Shared Neighborhood Hits	66
SwissProt Accessions	Q08376	Gene names	Zfp161, Zfp-5, Zfp5
Domain Architecture
Description	Zinc finger protein 161 (Zfp-161) (Zinc finger protein 5) (ZF5).

ZN232_HUMAN
θ value	3.0926 (rank : 2244)	NC score	-0.029600 (rank : 3112)
Query Neighborhood Hits	2923	Target Neighborhood Hits	754	Shared Neighborhood Hits	75
SwissProt Accessions	Q9UNY5	Gene names	ZNF232, ZSCAN11
Domain Architecture
Description	Zinc finger protein 232 (Zinc finger and SCAN domain-containing protein 11).

ZSCA5_HUMAN
θ value	3.0926 (rank : 2245)	NC score	-0.028654 (rank : 3102)
Query Neighborhood Hits	2923	Target Neighborhood Hits	862	Shared Neighborhood Hits	124
SwissProt Accessions	Q9BUG6	Gene names	ZSCAN5, ZNF495
Domain Architecture	No domain graphic available
Description	Zinc finger and SCAN domain-containing protein 5 (Zinc finger protein 495).

AAT1_HUMAN
θ value	4.03905 (rank : 2246)	NC score	0.026550 (rank : 2075)
Query Neighborhood Hits	2923	Target Neighborhood Hits	199	Shared Neighborhood Hits	128
SwissProt Accessions	Q7Z4T9, Q68DX2, Q8TD41, Q96A45, Q96JE8	Gene names	AAT1, C3orf15
Domain Architecture	No domain graphic available
Description	AMY-1-associating protein expressed in testis 1 (AAT-1).

ACO12_HUMAN
θ value	4.03905 (rank : 2247)	NC score	0.000258 (rank : 2832)
Query Neighborhood Hits	2923	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WYK0	Gene names	ACOT12, CACH, CACH1, STARD12
Domain Architecture
Description	Acyl-coenzyme A thioesterase 12 (EC 3.1.2.1) (Acyl-CoA thioesterase 12) (Acyl-CoA thioester hydrolase 12) (Cytoplasmic acetyl-CoA hydrolase 1) (CACH-1) (hCACH-1) (START domain-containing protein 12) (StARD12).

AMOT_HUMAN
θ value	4.03905 (rank : 2248)	NC score	0.054975 (rank : 1577)
Query Neighborhood Hits	2923	Target Neighborhood Hits	712	Shared Neighborhood Hits	349
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

ANTR1_HUMAN
θ value	4.03905 (rank : 2249)	NC score	0.018394 (rank : 2228)
Query Neighborhood Hits	2923	Target Neighborhood Hits	128	Shared Neighborhood Hits	78
SwissProt Accessions	Q9H6X2, Q96P02, Q9NVP3	Gene names	ANTXR1, ATR, TEM8
Domain Architecture
Description	Anthrax toxin receptor 1 precursor (Tumor endothelial marker 8).

ARRD2_HUMAN
θ value	4.03905 (rank : 2250)	NC score	-0.000161 (rank : 2845)
Query Neighborhood Hits	2923	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TBH0, O95895, Q6ZRV9, Q8WYG6	Gene names	ARRDC2
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 2.

ASPC1_MOUSE
θ value	4.03905 (rank : 2251)	NC score	0.009526 (rank : 2487)
Query Neighborhood Hits	2923	Target Neighborhood Hits	47	Shared Neighborhood Hits	24
SwissProt Accessions	Q8VBT9, Q3UKD1, Q6V7K5, Q9CT64	Gene names	Aspscr1, Tug
Domain Architecture	No domain graphic available
Description	Tether containing UBX domain for GLUT4 (Alveolar soft part sarcoma chromosome region candidate 1 homolog).

ATCAY_HUMAN
θ value	4.03905 (rank : 2252)	NC score	-0.000227 (rank : 2848)
Query Neighborhood Hits	2923	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	Q86WG3, Q8NAQ2, Q8TAQ3, Q96HC6, Q96JF5	Gene names	ATCAY, KIAA1872
Domain Architecture
Description	Caytaxin (Ataxia Cayman type protein) (BNIP-H).

ATS12_HUMAN
θ value	4.03905 (rank : 2253)	NC score	0.009248 (rank : 2502)
Query Neighborhood Hits	2923	Target Neighborhood Hits	251	Shared Neighborhood Hits	49
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATTY_MOUSE
θ value	4.03905 (rank : 2254)	NC score	0.001188 (rank : 2794)
Query Neighborhood Hits	2923	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q8QZR1, Q3UER7, Q8BTI1	Gene names	Tat
Domain Architecture
Description	Tyrosine aminotransferase (EC 2.6.1.5) (L-tyrosine:2-oxoglutarate aminotransferase) (TAT).

BAIP3_HUMAN
θ value	4.03905 (rank : 2255)	NC score	0.017307 (rank : 2254)
Query Neighborhood Hits	2923	Target Neighborhood Hits	108	Shared Neighborhood Hits	22
SwissProt Accessions	O94812, O94839, Q2M226, Q658J2, Q76N05, Q96RZ3, Q9UJK1	Gene names	BAIAP3, KIAA0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

BAZ2A_HUMAN
θ value	4.03905 (rank : 2256)	NC score	0.029481 (rank : 2012)
Query Neighborhood Hits	2923	Target Neighborhood Hits	780	Shared Neighborhood Hits	332
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

BAZ2B_HUMAN
θ value	4.03905 (rank : 2257)	NC score	0.040350 (rank : 1841)
Query Neighborhood Hits	2923	Target Neighborhood Hits	803	Shared Neighborhood Hits	349
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

BRD3_MOUSE
θ value	4.03905 (rank : 2258)	NC score	0.029560 (rank : 2010)
Query Neighborhood Hits	2923	Target Neighborhood Hits	402	Shared Neighborhood Hits	229
SwissProt Accessions	Q8K2F0, Q8C665, Q8CAX7, Q9JI25	Gene names	Brd3, Fsrg2
Domain Architecture
Description	Bromodomain-containing protein 3 (Bromodomain-containing FSH-like protein FSRG2).

BUB1B_HUMAN
θ value	4.03905 (rank : 2259)	NC score	0.098844 (rank : 1207)
Query Neighborhood Hits	2923	Target Neighborhood Hits	208	Shared Neighborhood Hits	159
SwissProt Accessions	O60566, O60501, O60627, O60758, O75389, Q96KM4	Gene names	BUB1B, BUBR1, MAD3L
Domain Architecture
Description	Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (hBUBR1) (MAD3/BUB1-related protein kinase) (Mitotic checkpoint kinase MAD3L) (SSK1).

CCD41_HUMAN
θ value	4.03905 (rank : 2260)	NC score	0.060739 (rank : 1422)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1139	Shared Neighborhood Hits	424
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

CCNK_HUMAN
θ value	4.03905 (rank : 2261)	NC score	0.007924 (rank : 2542)
Query Neighborhood Hits	2923	Target Neighborhood Hits	101	Shared Neighborhood Hits	58
SwissProt Accessions	O75909, Q96B63, Q9NNY9	Gene names	CCNK, CPR4
Domain Architecture
Description	Cyclin-K.

CD3G_MOUSE
θ value	4.03905 (rank : 2262)	NC score	0.010280 (rank : 2462)
Query Neighborhood Hits	2923	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	P11942	Gene names	Cd3g
Domain Architecture
Description	T-cell surface glycoprotein CD3 gamma chain precursor (T-cell receptor T3 gamma chain).

CHD6_HUMAN
θ value	4.03905 (rank : 2263)	NC score	0.009185 (rank : 2505)
Query Neighborhood Hits	2923	Target Neighborhood Hits	342	Shared Neighborhood Hits	142
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

CHD8_HUMAN
θ value	4.03905 (rank : 2264)	NC score	0.006007 (rank : 2604)
Query Neighborhood Hits	2923	Target Neighborhood Hits	235	Shared Neighborhood Hits	94
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

CNGA2_MOUSE
θ value	4.03905 (rank : 2265)	NC score	0.001602 (rank : 2775)
Query Neighborhood Hits	2923	Target Neighborhood Hits	86	Shared Neighborhood Hits	35
SwissProt Accessions	Q62398	Gene names	Cnga2, Cncg2, Cncg4
Domain Architecture
Description	Cyclic nucleotide-gated olfactory channel (Cyclic nucleotide-gated cation channel 2) (CNG channel 2) (CNG-2) (CNG2).

CO1A1_HUMAN
θ value	4.03905 (rank : 2266)	NC score	0.015234 (rank : 2315)
Query Neighborhood Hits	2923	Target Neighborhood Hits	475	Shared Neighborhood Hits	138
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CPNE3_MOUSE
θ value	4.03905 (rank : 2267)	NC score	0.004800 (rank : 2647)
Query Neighborhood Hits	2923	Target Neighborhood Hits	90	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BT60, Q5CZX9, Q5DU22	Gene names	Cpne3, Kiaa0636
Domain Architecture
Description	Copine-3 (Copine III).

CROP_HUMAN
θ value	4.03905 (rank : 2268)	NC score	0.039130 (rank : 1853)
Query Neighborhood Hits	2923	Target Neighborhood Hits	402	Shared Neighborhood Hits	207
SwissProt Accessions	O95232, Q6PHR9, Q9NUY0, Q9P2S7	Gene names	CROP, CREAP1, O48
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein (cAMP regulatory element-associated protein 1) (CRE-associated protein 1) (CREAP-1) (Luc7A) (Okadaic acid-inducible phosphoprotein OA48-18).

CROP_MOUSE
θ value	4.03905 (rank : 2269)	NC score	0.038583 (rank : 1864)
Query Neighborhood Hits	2923	Target Neighborhood Hits	403	Shared Neighborhood Hits	209
SwissProt Accessions	Q5SUF2, Q3U9D5, Q8BUJ5, Q921Z3, Q9CRS7, Q9CTY4	Gene names	Crop
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein.

DACH1_MOUSE
θ value	4.03905 (rank : 2270)	NC score	0.008638 (rank : 2518)
Query Neighborhood Hits	2923	Target Neighborhood Hits	228	Shared Neighborhood Hits	101
SwissProt Accessions	Q9QYB2, O88716, Q8BPQ0, Q8C8D7, Q9QY47, Q9R218, Q9Z0Y5	Gene names	Dach1, Dach
Domain Architecture
Description	Dachshund homolog 1 (Dach1).

DDX52_HUMAN
θ value	4.03905 (rank : 2271)	NC score	-0.008830 (rank : 3044)
Query Neighborhood Hits	2923	Target Neighborhood Hits	107	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y2R4, Q86YG1, Q8N213, Q9NVE0, Q9Y482	Gene names	DDX52, ROK1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DLG1_MOUSE
θ value	4.03905 (rank : 2272)	NC score	0.006052 (rank : 2602)
Query Neighborhood Hits	2923	Target Neighborhood Hits	285	Shared Neighborhood Hits	65
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

DPOLA_HUMAN
θ value	4.03905 (rank : 2273)	NC score	0.003359 (rank : 2712)
Query Neighborhood Hits	2923	Target Neighborhood Hits	41	Shared Neighborhood Hits	13
SwissProt Accessions	P09884, Q86UQ7	Gene names	POLA1, POLA
Domain Architecture
Description	DNA polymerase alpha catalytic subunit (EC 2.7.7.7).

DTD1_HUMAN
θ value	4.03905 (rank : 2274)	NC score	0.011182 (rank : 2435)
Query Neighborhood Hits	2923	Target Neighborhood Hits	50	Shared Neighborhood Hits	25
SwissProt Accessions	Q8TEA8, Q496D1, Q5W184, Q8WXU8, Q9BW67, Q9H464, Q9H474	Gene names	HARS2, C20orf88
Domain Architecture
Description	Probable D-tyrosyl-tRNA(Tyr) deacylase (EC 3.1.-.-).

DTD1_MOUSE
θ value	4.03905 (rank : 2275)	NC score	0.009981 (rank : 2472)
Query Neighborhood Hits	2923	Target Neighborhood Hits	37	Shared Neighborhood Hits	21
SwissProt Accessions	Q9DD18, Q9CRE8, Q9CYL0, Q9D013, Q9D1G4	Gene names	Hars2
Domain Architecture
Description	Probable D-tyrosyl-tRNA(Tyr) deacylase (EC 3.1.-.-).

EGF_HUMAN
θ value	4.03905 (rank : 2276)	NC score	0.007128 (rank : 2567)
Query Neighborhood Hits	2923	Target Neighborhood Hits	343	Shared Neighborhood Hits	67
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

EMIL2_HUMAN
θ value	4.03905 (rank : 2277)	NC score	0.028395 (rank : 2039)
Query Neighborhood Hits	2923	Target Neighborhood Hits	573	Shared Neighborhood Hits	262
SwissProt Accessions	Q9BXX0, Q8NBH3, Q96JQ4	Gene names	EMILIN2
Domain Architecture
Description	EMILIN-2 precursor (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Protein FOAP-10).

EP400_HUMAN
θ value	4.03905 (rank : 2278)	NC score	0.025347 (rank : 2102)
Query Neighborhood Hits	2923	Target Neighborhood Hits	556	Shared Neighborhood Hits	268
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

ETV6_HUMAN
θ value	4.03905 (rank : 2279)	NC score	-0.000609 (rank : 2863)
Query Neighborhood Hits	2923	Target Neighborhood Hits	120	Shared Neighborhood Hits	36
SwissProt Accessions	P41212, Q9UMF6	Gene names	ETV6, TEL, TEL1
Domain Architecture
Description	Transcription factor ETV6 (ETS-related protein Tel1) (Tel) (ETS translocation variant 6).

EVPL_HUMAN
θ value	4.03905 (rank : 2280)	NC score	0.056951 (rank : 1531)
Query Neighborhood Hits	2923	Target Neighborhood Hits	895	Shared Neighborhood Hits	380
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

FLIP1_MOUSE
θ value	4.03905 (rank : 2281)	NC score	0.057390 (rank : 1510)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1176	Shared Neighborhood Hits	454
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

GBP5_HUMAN
θ value	4.03905 (rank : 2282)	NC score	0.017888 (rank : 2239)
Query Neighborhood Hits	2923	Target Neighborhood Hits	200	Shared Neighborhood Hits	112
SwissProt Accessions	Q96PP8	Gene names	GBP5
Domain Architecture
Description	Interferon-induced guanylate-binding protein 5 (GTP-binding protein 5) (Guanine nucleotide-binding protein 5) (GBP-5) (GBP-TA antigen).

GIDRP_HUMAN
θ value	4.03905 (rank : 2283)	NC score	0.005397 (rank : 2615)
Query Neighborhood Hits	2923	Target Neighborhood Hits	49	Shared Neighborhood Hits	23
SwissProt Accessions	Q7Z5L2, O60598, Q5W0B4, Q5W0B5, Q86VT9, Q8N9H0	Gene names	GIDRP88, C10orf28
Domain Architecture	No domain graphic available
Description	Growth inhibition and differentiation-related protein 88 (Putative mitochondrial space protein 32.1).

GLI1_MOUSE
θ value	4.03905 (rank : 2284)	NC score	-0.028984 (rank : 3105)
Query Neighborhood Hits	2923	Target Neighborhood Hits	785	Shared Neighborhood Hits	85
SwissProt Accessions	P47806, Q9QYK1	Gene names	Gli1, Gli
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI1 (Glioma-associated oncogene homolog).

GP124_MOUSE
θ value	4.03905 (rank : 2285)	NC score	0.038362 (rank : 1868)
Query Neighborhood Hits	2923	Target Neighborhood Hits	423	Shared Neighborhood Hits	107
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

GP176_MOUSE
θ value	4.03905 (rank : 2286)	NC score	-0.024467 (rank : 3090)
Query Neighborhood Hits	2923	Target Neighborhood Hits	539	Shared Neighborhood Hits	16
SwissProt Accessions	Q80WT4, Q80UC4	Gene names	Gpr176, Agr9, Gm1012
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 176 (G-protein coupled receptor AGR9).

H15_HUMAN
θ value	4.03905 (rank : 2287)	NC score	0.016919 (rank : 2266)
Query Neighborhood Hits	2923	Target Neighborhood Hits	76	Shared Neighborhood Hits	35
SwissProt Accessions	P16401, Q14529	Gene names	HIST1H1B, H1F5
Domain Architecture
Description	Histone H1.5 (Histone H1a).

HPLN2_HUMAN
θ value	4.03905 (rank : 2288)	NC score	0.028943 (rank : 2027)
Query Neighborhood Hits	2923	Target Neighborhood Hits	80	Shared Neighborhood Hits	59
SwissProt Accessions	Q9GZV7	Gene names	HAPLN2, BRAL1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 2 precursor (Brain link protein 1).

HPLN2_MOUSE
θ value	4.03905 (rank : 2289)	NC score	0.040791 (rank : 1832)
Query Neighborhood Hits	2923	Target Neighborhood Hits	102	Shared Neighborhood Hits	86
SwissProt Accessions	Q9ESM3	Gene names	Hapln2, Bral1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 2 precursor (Brain link protein 1).

HRX_HUMAN
θ value	4.03905 (rank : 2290)	NC score	0.031467 (rank : 1991)
Query Neighborhood Hits	2923	Target Neighborhood Hits	825	Shared Neighborhood Hits	328
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

HSP74_MOUSE
θ value	4.03905 (rank : 2291)	NC score	0.015424 (rank : 2307)
Query Neighborhood Hits	2923	Target Neighborhood Hits	257	Shared Neighborhood Hits	134
SwissProt Accessions	Q61316	Gene names	Hspa4, Hsp110
Domain Architecture
Description	Heat shock 70 kDa protein 4 (Heat shock 70-related protein APG-2).

HXA3_MOUSE
θ value	4.03905 (rank : 2292)	NC score	-0.007791 (rank : 3028)
Query Neighborhood Hits	2923	Target Neighborhood Hits	558	Shared Neighborhood Hits	144
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

IDH3A_HUMAN
θ value	4.03905 (rank : 2293)	NC score	0.003215 (rank : 2721)
Query Neighborhood Hits	2923	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	P50213, Q9H3X0	Gene names	IDH3A
Domain Architecture
Description	Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH).

IDS_MOUSE
θ value	4.03905 (rank : 2294)	NC score	0.000666 (rank : 2817)
Query Neighborhood Hits	2923	Target Neighborhood Hits	36	Shared Neighborhood Hits	6
SwissProt Accessions	Q08890, Q3TM30	Gene names	Ids
Domain Architecture
Description	Iduronate 2-sulfatase precursor (EC 3.1.6.13) (Alpha-L-iduronate sulfate sulfatase).

IF4B_HUMAN
θ value	4.03905 (rank : 2295)	NC score	0.020770 (rank : 2186)
Query Neighborhood Hits	2923	Target Neighborhood Hits	417	Shared Neighborhood Hits	122
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

IL4RA_MOUSE
θ value	4.03905 (rank : 2296)	NC score	0.011998 (rank : 2415)
Query Neighborhood Hits	2923	Target Neighborhood Hits	194	Shared Neighborhood Hits	80
SwissProt Accessions	P16382, O54690, Q60583, Q8CBW5	Gene names	Il4r, Il4ra
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (IL-4- binding protein) (IL4-BP)].

ITPR1_HUMAN
θ value	4.03905 (rank : 2297)	NC score	0.002551 (rank : 2742)
Query Neighborhood Hits	2923	Target Neighborhood Hits	90	Shared Neighborhood Hits	33
SwissProt Accessions	Q14643, Q14660, Q99897	Gene names	ITPR1, INSP3R1
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 1 (Type 1 inositol 1,4,5- trisphosphate receptor) (Type 1 InsP3 receptor) (IP3 receptor isoform 1) (InsP3R1) (IP3R).

K1024_HUMAN
θ value	4.03905 (rank : 2298)	NC score	0.003285 (rank : 2715)
Query Neighborhood Hits	2923	Target Neighborhood Hits	66	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UPX6	Gene names	KIAA1024
Domain Architecture
Description	UPF0258 protein KIAA1024.

KU86_MOUSE
θ value	4.03905 (rank : 2299)	NC score	0.004943 (rank : 2638)
Query Neighborhood Hits	2923	Target Neighborhood Hits	23	Shared Neighborhood Hits	12
SwissProt Accessions	P27641	Gene names	Xrcc5, G22p2
Domain Architecture
Description	ATP-dependent DNA helicase 2 subunit 2 (EC 3.6.1.-) (ATP-dependent DNA helicase II 80 kDa subunit) (Ku autoantigen protein p86 homolog) (Ku80) (CTC box-binding factor 85 kDa subunit) (CTCBF) (CTC85) (Nuclear factor IV) (DNA-repair protein XRCC5).

KV3H_HUMAN
θ value	4.03905 (rank : 2300)	NC score	-0.000184 (rank : 2847)
Query Neighborhood Hits	2923	Target Neighborhood Hits	285	Shared Neighborhood Hits	82
SwissProt Accessions	P04207	Gene names
Domain Architecture
Description	Ig kappa chain V-III region CLL precursor (Rheumatoid factor).

KV3I_MOUSE
θ value	4.03905 (rank : 2301)	NC score	-0.004401 (rank : 2964)
Query Neighborhood Hits	2923	Target Neighborhood Hits	242	Shared Neighborhood Hits	70
SwissProt Accessions	P01661	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-III region MOPC 63 precursor.

KV3J_MOUSE
θ value	4.03905 (rank : 2302)	NC score	-0.004381 (rank : 2963)
Query Neighborhood Hits	2923	Target Neighborhood Hits	242	Shared Neighborhood Hits	71
SwissProt Accessions	P01662	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-III region ABPC 22/PC 9245.

KV3K_MOUSE
θ value	4.03905 (rank : 2303)	NC score	-0.004600 (rank : 2965)
Query Neighborhood Hits	2923	Target Neighborhood Hits	241	Shared Neighborhood Hits	69
SwissProt Accessions	P01663	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-III region PC 4050.

KV5B_MOUSE
θ value	4.03905 (rank : 2304)	NC score	0.000960 (rank : 2803)
Query Neighborhood Hits	2923	Target Neighborhood Hits	253	Shared Neighborhood Hits	87
SwissProt Accessions	P01634	Gene names
Domain Architecture
Description	Ig kappa chain V-V region MOPC 21 precursor.

LDB3_MOUSE
θ value	4.03905 (rank : 2305)	NC score	0.010992 (rank : 2446)
Query Neighborhood Hits	2923	Target Neighborhood Hits	510	Shared Neighborhood Hits	170
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

LHX4_HUMAN
θ value	4.03905 (rank : 2306)	NC score	-0.013738 (rank : 3071)
Query Neighborhood Hits	2923	Target Neighborhood Hits	455	Shared Neighborhood Hits	30
SwissProt Accessions	Q969G2, Q8NHE0, Q8TCJ1, Q8WWX2, Q969W2	Gene names	LHX4
Domain Architecture
Description	LIM/homeobox protein Lhx4.

LIMA1_MOUSE
θ value	4.03905 (rank : 2307)	NC score	0.007295 (rank : 2557)
Query Neighborhood Hits	2923	Target Neighborhood Hits	298	Shared Neighborhood Hits	88
SwissProt Accessions	Q9ERG0, Q9ERG1	Gene names	Lima1, D15Ertd366e, Eplin
Domain Architecture
Description	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm) (mEPLIN).

LIPB2_HUMAN
θ value	4.03905 (rank : 2308)	NC score	0.034583 (rank : 1938)
Query Neighborhood Hits	2923	Target Neighborhood Hits	599	Shared Neighborhood Hits	260
SwissProt Accessions	Q8ND30, O75337, Q8WW26	Gene names	PPFIBP2
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2).

LTB1L_MOUSE
θ value	4.03905 (rank : 2309)	NC score	0.016187 (rank : 2285)
Query Neighborhood Hits	2923	Target Neighborhood Hits	514	Shared Neighborhood Hits	100
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	4.03905 (rank : 2310)	NC score	0.016108 (rank : 2288)
Query Neighborhood Hits	2923	Target Neighborhood Hits	479	Shared Neighborhood Hits	92
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LV4B_HUMAN
θ value	4.03905 (rank : 2311)	NC score	0.000208 (rank : 2834)
Query Neighborhood Hits	2923	Target Neighborhood Hits	202	Shared Neighborhood Hits	70
SwissProt Accessions	P01716	Gene names
Domain Architecture	No domain graphic available
Description	Ig lambda chain V-IV region X.

LV6A_HUMAN
θ value	4.03905 (rank : 2312)	NC score	-0.004616 (rank : 2966)
Query Neighborhood Hits	2923	Target Neighborhood Hits	284	Shared Neighborhood Hits	75
SwissProt Accessions	P01721	Gene names
Domain Architecture	No domain graphic available
Description	Ig lambda chain V-VI region AR.

LZTS1_MOUSE
θ value	4.03905 (rank : 2313)	NC score	0.039790 (rank : 1846)
Query Neighborhood Hits	2923	Target Neighborhood Hits	540	Shared Neighborhood Hits	259
SwissProt Accessions	P60853	Gene names	Lzts1, Fez1
Domain Architecture	No domain graphic available
Description	Leucine zipper putative tumor suppressor 1 (F37/Esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

MAML2_HUMAN
θ value	4.03905 (rank : 2314)	NC score	0.023513 (rank : 2137)
Query Neighborhood Hits	2923	Target Neighborhood Hits	360	Shared Neighborhood Hits	152
SwissProt Accessions	Q8IZL2, Q6AI23, Q6Y3A3, Q8IUL3, Q96JK6	Gene names	MAML2, KIAA1819
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 2 (Mam-2).

MAP9_MOUSE
θ value	4.03905 (rank : 2315)	NC score	0.046569 (rank : 1745)
Query Neighborhood Hits	2923	Target Neighborhood Hits	529	Shared Neighborhood Hits	258
SwissProt Accessions	Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7	Gene names	Map9, Asap
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

MIS_MOUSE
θ value	4.03905 (rank : 2316)	NC score	-0.002214 (rank : 2911)
Query Neighborhood Hits	2923	Target Neighborhood Hits	86	Shared Neighborhood Hits	10
SwissProt Accessions	P27106	Gene names	Amh
Domain Architecture
Description	Muellerian-inhibiting factor precursor (MIS) (Anti-Muellerian hormone) (AMH) (Muellerian-inhibiting substance).

MPRI_HUMAN
θ value	4.03905 (rank : 2317)	NC score	0.008967 (rank : 2509)
Query Neighborhood Hits	2923	Target Neighborhood Hits	67	Shared Neighborhood Hits	21
SwissProt Accessions	P11717, Q7Z7G9, Q96PT5	Gene names	IGF2R, MPRI
Domain Architecture
Description	Cation-independent mannose-6-phosphate receptor precursor (CI Man-6-P receptor) (CI-MPR) (M6PR) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (300 kDa mannose 6-phosphate receptor) (MPR 300) (MPR300) (CD222 antigen).

MYH10_MOUSE
θ value	4.03905 (rank : 2318)	NC score	0.054104 (rank : 1610)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1612	Shared Neighborhood Hits	531
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH11_HUMAN
θ value	4.03905 (rank : 2319)	NC score	0.056117 (rank : 1552)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1806	Shared Neighborhood Hits	572
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH13_HUMAN
θ value	4.03905 (rank : 2320)	NC score	0.052450 (rank : 1652)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1504	Shared Neighborhood Hits	467
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

MYO6_MOUSE
θ value	4.03905 (rank : 2321)	NC score	0.041572 (rank : 1819)
Query Neighborhood Hits	2923	Target Neighborhood Hits	586	Shared Neighborhood Hits	286
SwissProt Accessions	Q64331	Gene names	Myo6, Sv
Domain Architecture
Description	Myosin-6 (Myosin VI).

NASP_HUMAN
θ value	4.03905 (rank : 2322)	NC score	0.048645 (rank : 1725)
Query Neighborhood Hits	2923	Target Neighborhood Hits	709	Shared Neighborhood Hits	300
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

NCOA2_HUMAN
θ value	4.03905 (rank : 2323)	NC score	0.000555 (rank : 2822)
Query Neighborhood Hits	2923	Target Neighborhood Hits	281	Shared Neighborhood Hits	73
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

NCTR1_HUMAN
θ value	4.03905 (rank : 2324)	NC score	0.011062 (rank : 2439)
Query Neighborhood Hits	2923	Target Neighborhood Hits	44	Shared Neighborhood Hits	24
SwissProt Accessions	O76036, O76016, O76017, O76018	Gene names	NCR1, LY94
Domain Architecture	No domain graphic available
Description	Natural cytotoxicity triggering receptor 1 precursor (Natural killer cell p46-related protein) (NKp46) (hNKp46) (NK-p46) (NK cell- activating receptor) (Lymphocyte antigen 94 homolog) (CD335 antigen).

NLGN2_HUMAN
θ value	4.03905 (rank : 2325)	NC score	-0.000315 (rank : 2852)
Query Neighborhood Hits	2923	Target Neighborhood Hits	55	Shared Neighborhood Hits	18
SwissProt Accessions	Q8NFZ4, Q9P2I1	Gene names	NLGN2, KIAA1366
Domain Architecture
Description	Neuroligin-2 precursor.

NLGN2_MOUSE
θ value	4.03905 (rank : 2326)	NC score	-0.000526 (rank : 2858)
Query Neighborhood Hits	2923	Target Neighborhood Hits	49	Shared Neighborhood Hits	15
SwissProt Accessions	Q69ZK9, Q5F288	Gene names	Nlgn2, Kiaa1366
Domain Architecture	No domain graphic available
Description	Neuroligin-2 precursor.

NOC3L_MOUSE
θ value	4.03905 (rank : 2327)	NC score	0.017603 (rank : 2248)
Query Neighborhood Hits	2923	Target Neighborhood Hits	177	Shared Neighborhood Hits	93
SwissProt Accessions	Q8VI84, Q9JKM3	Gene names	Noc3l, Ad24, Fad24
Domain Architecture	No domain graphic available
Description	Nucleolar complex protein 3 homolog (NOC3 protein homolog) (NOC3-like protein) (Nucleolar complex-associated protein 3-like protein) (Factor for adipocyte differentiation 24).

NOS3_MOUSE
θ value	4.03905 (rank : 2328)	NC score	-0.000513 (rank : 2857)
Query Neighborhood Hits	2923	Target Neighborhood Hits	63	Shared Neighborhood Hits	18
SwissProt Accessions	P70313, O55056	Gene names	Nos3, Ecnos
Domain Architecture
Description	Nitric-oxide synthase, endothelial (EC 1.14.13.39) (EC-NOS) (NOS type III) (NOSIII) (Endothelial NOS) (eNOS) (Constitutive NOS) (cNOS).

PCDA5_HUMAN
θ value	4.03905 (rank : 2329)	NC score	-0.007292 (rank : 3011)
Query Neighborhood Hits	2923	Target Neighborhood Hits	217	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y5H7, O75284, Q8N4R3	Gene names	PCDHA5
Domain Architecture
Description	Protocadherin alpha 5 precursor (PCDH-alpha5).

PDCD1_MOUSE
θ value	4.03905 (rank : 2330)	NC score	0.013077 (rank : 2382)
Query Neighborhood Hits	2923	Target Neighborhood Hits	28	Shared Neighborhood Hits	14
SwissProt Accessions	Q02242	Gene names	Pdcd1, Pd1
Domain Architecture
Description	Programmed cell death protein 1 precursor (Protein PD-1) (mPD-1) (CD279 antigen).

PHF2_MOUSE
θ value	4.03905 (rank : 2331)	NC score	0.015640 (rank : 2298)
Query Neighborhood Hits	2923	Target Neighborhood Hits	241	Shared Neighborhood Hits	103
SwissProt Accessions	Q9WTU0, Q80WA8	Gene names	Phf2
Domain Architecture
Description	PHD finger protein 2 (GRC5).

PINK1_MOUSE
θ value	4.03905 (rank : 2332)	NC score	0.611666 (rank : 612)
Query Neighborhood Hits	2923	Target Neighborhood Hits	726	Shared Neighborhood Hits	685
SwissProt Accessions	Q99MQ3, Q7TMZ3, Q811I8, Q91XU5	Gene names	Pink1
Domain Architecture
Description	Serine/threonine-protein kinase PINK1, mitochondrial precursor (EC 2.7.11.1) (PTEN-induced putative kinase protein 1) (BRPK).

PITM2_HUMAN
θ value	4.03905 (rank : 2333)	NC score	0.000001 (rank : 2838)
Query Neighborhood Hits	2923	Target Neighborhood Hits	52	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BZ72, Q9P271	Gene names	PITPNM2, KIAA1457, NIR3
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 2 (Phosphatidylinositol transfer protein, membrane-associated 2) (Pyk2 N-terminal domain-interacting receptor 3) (NIR-3).

PPP5_HUMAN
θ value	4.03905 (rank : 2334)	NC score	-0.007472 (rank : 3021)
Query Neighborhood Hits	2923	Target Neighborhood Hits	101	Shared Neighborhood Hits	12
SwissProt Accessions	P53041, Q16722	Gene names	PPP5C, PPP5
Domain Architecture
Description	Serine/threonine-protein phosphatase 5 (EC 3.1.3.16) (PP5) (Protein phosphatase T) (PP-T) (PPT).

PPRB_MOUSE
θ value	4.03905 (rank : 2335)	NC score	0.029203 (rank : 2021)
Query Neighborhood Hits	2923	Target Neighborhood Hits	354	Shared Neighborhood Hits	140
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

PTCD1_HUMAN
θ value	4.03905 (rank : 2336)	NC score	0.006981 (rank : 2574)
Query Neighborhood Hits	2923	Target Neighborhood Hits	52	Shared Neighborhood Hits	28
SwissProt Accessions	O75127, Q66K60, Q9UDV2	Gene names	PTCD1, KIAA0632
Domain Architecture	No domain graphic available
Description	Pentatricopeptide repeat protein 1.

PTN21_MOUSE
θ value	4.03905 (rank : 2337)	NC score	0.035852 (rank : 1907)
Query Neighborhood Hits	2923	Target Neighborhood Hits	155	Shared Neighborhood Hits	54
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

RAPH1_HUMAN
θ value	4.03905 (rank : 2338)	NC score	0.055338 (rank : 1569)
Query Neighborhood Hits	2923	Target Neighborhood Hits	593	Shared Neighborhood Hits	271
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

RB6I2_MOUSE
θ value	4.03905 (rank : 2339)	NC score	0.061290 (rank : 1409)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1433	Shared Neighborhood Hits	502
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

RBBP5_HUMAN
θ value	4.03905 (rank : 2340)	NC score	-0.004809 (rank : 2972)
Query Neighborhood Hits	2923	Target Neighborhood Hits	372	Shared Neighborhood Hits	79
SwissProt Accessions	Q15291	Gene names	RBBP5, RBQ3
Domain Architecture
Description	Retinoblastoma-binding protein 5 (RBBP-5) (Retinoblastoma-binding protein RBQ-3).

REPS1_HUMAN
θ value	4.03905 (rank : 2341)	NC score	0.010035 (rank : 2470)
Query Neighborhood Hits	2923	Target Neighborhood Hits	205	Shared Neighborhood Hits	84
SwissProt Accessions	Q96D71, Q8NDR7, Q8WU62, Q9BXY9	Gene names	REPS1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

RFC1_MOUSE
θ value	4.03905 (rank : 2342)	NC score	0.018061 (rank : 2236)
Query Neighborhood Hits	2923	Target Neighborhood Hits	290	Shared Neighborhood Hits	127
SwissProt Accessions	P35601	Gene names	Rfc1, Ibf-1, Recc1
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (A1-P145) (Differentiation- specific element-binding protein) (ISRE-binding protein).

RIMB1_MOUSE
θ value	4.03905 (rank : 2343)	NC score	0.075783 (rank : 1277)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1376	Shared Neighborhood Hits	531
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RL7_MOUSE
θ value	4.03905 (rank : 2344)	NC score	0.004361 (rank : 2666)
Query Neighborhood Hits	2923	Target Neighborhood Hits	15	Shared Neighborhood Hits	9
SwissProt Accessions	P14148, Q80UR0	Gene names	Rpl7
Domain Architecture
Description	60S ribosomal protein L7.

RNF25_HUMAN
θ value	4.03905 (rank : 2345)	NC score	0.011728 (rank : 2419)
Query Neighborhood Hits	2923	Target Neighborhood Hits	163	Shared Neighborhood Hits	57
SwissProt Accessions	Q96BH1, Q9H874	Gene names	RNF25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-).

RRBP1_HUMAN
θ value	4.03905 (rank : 2346)	NC score	0.054711 (rank : 1585)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1306	Shared Neighborhood Hits	479
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

RS3_HUMAN
θ value	4.03905 (rank : 2347)	NC score	0.006405 (rank : 2591)
Query Neighborhood Hits	2923	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	P23396, Q498B5, Q8NI95	Gene names	RPS3
Domain Architecture
Description	40S ribosomal protein S3.

RS3_MOUSE
θ value	4.03905 (rank : 2348)	NC score	0.006386 (rank : 2592)
Query Neighborhood Hits	2923	Target Neighborhood Hits	13	Shared Neighborhood Hits	7
SwissProt Accessions	P62908, P17073, P47933	Gene names	Rps3
Domain Architecture	No domain graphic available
Description	40S ribosomal protein S3.

S12A5_MOUSE
θ value	4.03905 (rank : 2349)	NC score	-0.002590 (rank : 2922)
Query Neighborhood Hits	2923	Target Neighborhood Hits	59	Shared Neighborhood Hits	12
SwissProt Accessions	Q91V14, Q9Z0M7	Gene names	Slc12a5, Kcc2
Domain Architecture
Description	Solute carrier family 12 member 5 (Electroneutral potassium-chloride cotransporter 2) (K-Cl cotransporter 2) (Neuronal K-Cl cotransporter) (mKCC2).

S27A1_HUMAN
θ value	4.03905 (rank : 2350)	NC score	-0.002598 (rank : 2924)
Query Neighborhood Hits	2923	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q6PCB7	Gene names	SLC27A1, ACSVL5, FATP1
Domain Architecture	No domain graphic available
Description	Long-chain fatty acid transport protein 1 (EC 6.2.1.-) (Fatty acid transport protein 1) (FATP-1) (Solute carrier family 27 member 1).

SAP_MOUSE
θ value	4.03905 (rank : 2351)	NC score	0.002740 (rank : 2736)
Query Neighborhood Hits	2923	Target Neighborhood Hits	22	Shared Neighborhood Hits	6
SwissProt Accessions	Q61207, Q60861, Q64006, Q64219	Gene names	Psap, Sgp1
Domain Architecture
Description	Sulfated glycoprotein 1 precursor (SGP-1) (Prosaposin).

SCN3B_HUMAN
θ value	4.03905 (rank : 2352)	NC score	0.021045 (rank : 2183)
Query Neighborhood Hits	2923	Target Neighborhood Hits	85	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NY72, Q9ULR2	Gene names	SCN3B, KIAA1158
Domain Architecture
Description	Sodium channel beta-3 subunit precursor.

SCN3B_MOUSE
θ value	4.03905 (rank : 2353)	NC score	0.025025 (rank : 2106)
Query Neighborhood Hits	2923	Target Neighborhood Hits	89	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BHK2, Q91Z99	Gene names	Scn3b
Domain Architecture
Description	Sodium channel beta-3 subunit precursor.

SEM3D_HUMAN
θ value	4.03905 (rank : 2354)	NC score	0.009891 (rank : 2474)
Query Neighborhood Hits	2923	Target Neighborhood Hits	104	Shared Neighborhood Hits	53
SwissProt Accessions	O95025, Q6UW77, Q8NCQ1	Gene names	SEMA3D
Domain Architecture
Description	Semaphorin-3D precursor.

SI1L3_HUMAN
θ value	4.03905 (rank : 2355)	NC score	0.008652 (rank : 2516)
Query Neighborhood Hits	2923	Target Neighborhood Hits	305	Shared Neighborhood Hits	120
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

SLAF6_MOUSE
θ value	4.03905 (rank : 2356)	NC score	0.034786 (rank : 1932)
Query Neighborhood Hits	2923	Target Neighborhood Hits	42	Shared Neighborhood Hits	37
SwissProt Accessions	Q9ET39, Q9ET40	Gene names	Slamf6, Ly108
Domain Architecture	No domain graphic available
Description	SLAM family member 6 precursor (Lymphocyte antigen 108).

SMPX_MOUSE
θ value	4.03905 (rank : 2357)	NC score	0.011552 (rank : 2425)
Query Neighborhood Hits	2923	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	Q9DC77, Q4QRM9, Q8CEX8, Q9ER98	Gene names	Smpx, Csl
Domain Architecture	No domain graphic available
Description	Small muscular protein (Stretch-responsive skeletal muscle protein) (Chisel protein).

SMRC2_MOUSE
θ value	4.03905 (rank : 2358)	NC score	0.020468 (rank : 2195)
Query Neighborhood Hits	2923	Target Neighborhood Hits	487	Shared Neighborhood Hits	193
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

SSX2_HUMAN
θ value	4.03905 (rank : 2359)	NC score	-0.001157 (rank : 2885)
Query Neighborhood Hits	2923	Target Neighborhood Hits	88	Shared Neighborhood Hits	14
SwissProt Accessions	Q16385, Q16404, Q5JS26, Q96IP7, Q9BU88	Gene names	SSX2
Domain Architecture
Description	Protein SSX2 (Synovial sarcoma, X breakpoint 2) (SSX) (HOM-MEL-40).

SYLC_MOUSE
θ value	4.03905 (rank : 2360)	NC score	0.001648 (rank : 2773)
Query Neighborhood Hits	2923	Target Neighborhood Hits	25	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BMJ2, Q8BKW9	Gene names	Lars
Domain Architecture
Description	Leucyl-tRNA synthetase, cytoplasmic (EC 6.1.1.4) (Leucine--tRNA ligase) (LeuRS).

TCRG1_HUMAN
θ value	4.03905 (rank : 2361)	NC score	0.072306 (rank : 1296)
Query Neighborhood Hits	2923	Target Neighborhood Hits	929	Shared Neighborhood Hits	458
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TNR6A_HUMAN
θ value	4.03905 (rank : 2362)	NC score	0.014418 (rank : 2344)
Query Neighborhood Hits	2923	Target Neighborhood Hits	343	Shared Neighborhood Hits	126
SwissProt Accessions	Q8NDV7, O15408, Q658L5, Q6NVB5, Q8NEZ0, Q8TBT8, Q8TCR0, Q9NV59, Q9P268	Gene names	TNRC6A, CAGH26, KIAA1460, TNRC6
Domain Architecture	No domain graphic available
Description	Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (Glycine-tryptophan protein of 182 kDa) (GW182 autoantigen) (Protein GW1) (EMSY interactor protein).

TOPB1_MOUSE
θ value	4.03905 (rank : 2363)	NC score	0.007199 (rank : 2559)
Query Neighborhood Hits	2923	Target Neighborhood Hits	89	Shared Neighborhood Hits	38
SwissProt Accessions	Q6ZQF0, Q6P6P0, Q80Y33, Q8BUI0, Q8BUK1, Q8R348, Q91VX3, Q922X8	Gene names	Topbp1, Kiaa0259
Domain Architecture	No domain graphic available
Description	DNA topoisomerase II-binding protein 1 (DNA topoisomerase IIbeta- binding protein 1) (TopBP1).

TXND5_HUMAN
θ value	4.03905 (rank : 2364)	NC score	0.003629 (rank : 2702)
Query Neighborhood Hits	2923	Target Neighborhood Hits	54	Shared Neighborhood Hits	12
SwissProt Accessions	Q8NBS9, Q8ND33, Q8TCT2, Q9BVH9	Gene names	TXNDC5, TLP46
Domain Architecture
Description	Thioredoxin domain-containing protein 5 precursor (Thioredoxin-like protein p46) (Endoplasmic reticulum protein ERp46).

UN13A_HUMAN
θ value	4.03905 (rank : 2365)	NC score	0.069610 (rank : 1310)
Query Neighborhood Hits	2923	Target Neighborhood Hits	285	Shared Neighborhood Hits	98
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

VAT1_MOUSE
θ value	4.03905 (rank : 2366)	NC score	-0.001482 (rank : 2895)
Query Neighborhood Hits	2923	Target Neighborhood Hits	41	Shared Neighborhood Hits	8
SwissProt Accessions	Q62465, Q8R3G0, Q8R3T8	Gene names	Vat1, Vat-1
Domain Architecture	No domain graphic available
Description	Synaptic vesicle membrane protein VAT-1 homolog (EC 1.-.-.-).

WHRN_HUMAN
θ value	4.03905 (rank : 2367)	NC score	0.002397 (rank : 2749)
Query Neighborhood Hits	2923	Target Neighborhood Hits	325	Shared Neighborhood Hits	84
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

ZN143_MOUSE
θ value	4.03905 (rank : 2368)	NC score	-0.029954 (rank : 3116)
Query Neighborhood Hits	2923	Target Neighborhood Hits	718	Shared Neighborhood Hits	65
SwissProt Accessions	O70230	Gene names	Znf143, Staf, Zfp143
Domain Architecture	No domain graphic available
Description	Zinc finger protein 143 (Zfp-143) (Selenocysteine tRNA gene transcription-activating factor) (mStaf).

ZNF7_HUMAN
θ value	4.03905 (rank : 2369)	NC score	-0.030015 (rank : 3118)
Query Neighborhood Hits	2923	Target Neighborhood Hits	770	Shared Neighborhood Hits	71
SwissProt Accessions	P17097, P17015	Gene names	ZNF7, KOX4
Domain Architecture
Description	Zinc finger protein 7 (Zinc finger protein KOX4) (Zinc finger protein HF.16).

ZRF1_HUMAN
θ value	4.03905 (rank : 2370)	NC score	0.032992 (rank : 1968)
Query Neighborhood Hits	2923	Target Neighborhood Hits	457	Shared Neighborhood Hits	216
SwissProt Accessions	Q99543	Gene names	ZRF1, DNAJC2, MPHOSPH11, MPP11
Domain Architecture
Description	Zuotin-related factor 1 (M-phase phosphoprotein 11).

2B18_HUMAN
θ value	5.27518 (rank : 2371)	NC score	0.000890 (rank : 2809)
Query Neighborhood Hits	2923	Target Neighborhood Hits	210	Shared Neighborhood Hits	56
SwissProt Accessions	Q30134, O19718, O19788, Q29968, Q30108, Q30115, Q9BCP0, Q9BCP1, Q9BCP2, Q9BD33, Q9TQ37, Q9UIM9	Gene names	HLA-DRB1
Domain Architecture
Description	HLA class II histocompatibility antigen, DRB1-8 beta chain precursor (MHC class I antigen DRB1*8) (DR-8) (DR8) (DRw8).

2B1B_HUMAN
θ value	5.27518 (rank : 2372)	NC score	0.001013 (rank : 2801)
Query Neighborhood Hits	2923	Target Neighborhood Hits	208	Shared Neighborhood Hits	56
SwissProt Accessions	P20039, Q30006, Q9GIX8	Gene names	HLA-DRB1
Domain Architecture
Description	HLA class II histocompatibility antigen, DRB1-11 beta chain precursor (MHC class I antigen DRB1*11) (DR-5) (DR5) (DRw11).

2DMB_HUMAN
θ value	5.27518 (rank : 2373)	NC score	0.003492 (rank : 2708)
Query Neighborhood Hits	2923	Target Neighborhood Hits	216	Shared Neighborhood Hits	63
SwissProt Accessions	P28068, O77936, Q13012, Q29751, Q9XRX2	Gene names	HLA-DMB, DMB, RING7
Domain Architecture
Description	HLA class II histocompatibility antigen, DM beta chain precursor (MHC class II antigen DMB).

A20A1_HUMAN
θ value	5.27518 (rank : 2374)	NC score	0.025981 (rank : 2088)
Query Neighborhood Hits	2923	Target Neighborhood Hits	698	Shared Neighborhood Hits	249
SwissProt Accessions	Q5TYW2, Q9H0H6	Gene names	ANKRD20A1, ANKRD20A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A1.

A20A2_HUMAN
θ value	5.27518 (rank : 2375)	NC score	0.025568 (rank : 2098)
Query Neighborhood Hits	2923	Target Neighborhood Hits	716	Shared Neighborhood Hits	254
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

A20A3_HUMAN
θ value	5.27518 (rank : 2376)	NC score	0.025562 (rank : 2099)
Query Neighborhood Hits	2923	Target Neighborhood Hits	692	Shared Neighborhood Hits	252
SwissProt Accessions	Q5VUR7	Gene names	ANKRD20A3
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A3.

A20A4_HUMAN
θ value	5.27518 (rank : 2377)	NC score	0.026272 (rank : 2082)
Query Neighborhood Hits	2923	Target Neighborhood Hits	710	Shared Neighborhood Hits	256
SwissProt Accessions	Q5SQ80	Gene names	ANKRD20A4
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A4.

AGM1_MOUSE
θ value	5.27518 (rank : 2378)	NC score	0.002586 (rank : 2738)
Query Neighborhood Hits	2923	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CYR6, Q543F9	Gene names	Pgm3, Agm1, Pgm-3
Domain Architecture
Description	Phosphoacetylglucosamine mutase (EC 5.4.2.3) (PAGM) (Acetylglucosamine phosphomutase) (N-acetylglucosamine-phosphate mutase) (Phosphoglucomutase 3).

AHTF1_HUMAN
θ value	5.27518 (rank : 2379)	NC score	0.021254 (rank : 2178)
Query Neighborhood Hits	2923	Target Neighborhood Hits	286	Shared Neighborhood Hits	129
SwissProt Accessions	Q8WYP5, Q7Z4E3, Q8IZA4, Q96EH9, Q9Y4Q6	Gene names	AHCTF1, ELYS, TMBS62
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

AINX_MOUSE
θ value	5.27518 (rank : 2380)	NC score	0.012085 (rank : 2412)
Query Neighborhood Hits	2923	Target Neighborhood Hits	448	Shared Neighborhood Hits	196
SwissProt Accessions	P46660, Q61958, Q8VCW5	Gene names	Ina
Domain Architecture
Description	Alpha-internexin (Alpha-Inx) (66 kDa neurofilament protein) (Neurofilament-66) (NF-66).

AIP_HUMAN
θ value	5.27518 (rank : 2381)	NC score	0.000132 (rank : 2836)
Query Neighborhood Hits	2923	Target Neighborhood Hits	51	Shared Neighborhood Hits	9
SwissProt Accessions	O00170, Q99606	Gene names	AIP, XAP2
Domain Architecture
Description	AH receptor-interacting protein (AIP) (Aryl-hydrocarbon receptor- interacting protein) (Immunophilin homolog ARA9) (HBV-X-associated protein 2).

AIRE_MOUSE
θ value	5.27518 (rank : 2382)	NC score	0.001994 (rank : 2762)
Query Neighborhood Hits	2923	Target Neighborhood Hits	196	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

AMGO2_MOUSE
θ value	5.27518 (rank : 2383)	NC score	0.067016 (rank : 1330)
Query Neighborhood Hits	2923	Target Neighborhood Hits	329	Shared Neighborhood Hits	124
SwissProt Accessions	Q80ZD9	Gene names	Amigo2, Ali1
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 2 precursor (AMIGO-2) (Alivin-1).

ANLN_HUMAN
θ value	5.27518 (rank : 2384)	NC score	0.016461 (rank : 2278)
Query Neighborhood Hits	2923	Target Neighborhood Hits	222	Shared Neighborhood Hits	103
SwissProt Accessions	Q9NQW6, Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0	Gene names	ANLN
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

ASPM_MOUSE
θ value	5.27518 (rank : 2385)	NC score	0.009486 (rank : 2490)
Query Neighborhood Hits	2923	Target Neighborhood Hits	150	Shared Neighborhood Hits	55
SwissProt Accessions	Q8CJ27, O88482, Q8BJI8, Q8BKT4	Gene names	Aspm, Calmbp1, Sha1
Domain Architecture
Description	Abnormal spindle-like microcephaly-associated protein homolog (Calmodulin-binding protein 1) (Spindle and hydroxyurea checkpoint abnormal protein) (Calmodulin-binding protein Sha1).

ASPP2_HUMAN
θ value	5.27518 (rank : 2386)	NC score	0.050659 (rank : 1687)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1156	Shared Neighborhood Hits	429
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

BAZ1A_HUMAN
θ value	5.27518 (rank : 2387)	NC score	0.032733 (rank : 1976)
Query Neighborhood Hits	2923	Target Neighborhood Hits	693	Shared Neighborhood Hits	335
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

BAZ1B_HUMAN
θ value	5.27518 (rank : 2388)	NC score	0.029008 (rank : 2025)
Query Neighborhood Hits	2923	Target Neighborhood Hits	701	Shared Neighborhood Hits	316
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

BBX_HUMAN
θ value	5.27518 (rank : 2389)	NC score	0.001467 (rank : 2780)
Query Neighborhood Hits	2923	Target Neighborhood Hits	167	Shared Neighborhood Hits	65
SwissProt Accessions	Q8WY36, Q2TAJ1, Q7L3J8, Q7LBY8, Q8NDB0, Q8WY35, Q9H0J6	Gene names	BBX, HBP2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

BPAEA_HUMAN
θ value	5.27518 (rank : 2390)	NC score	0.045461 (rank : 1759)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1369	Shared Neighborhood Hits	447
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

BRD3_HUMAN
θ value	5.27518 (rank : 2391)	NC score	0.026883 (rank : 2066)
Query Neighborhood Hits	2923	Target Neighborhood Hits	369	Shared Neighborhood Hits	212
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

BSN_HUMAN
θ value	5.27518 (rank : 2392)	NC score	0.078492 (rank : 1269)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1537	Shared Neighborhood Hits	603
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

BTLA_MOUSE
θ value	5.27518 (rank : 2393)	NC score	0.023182 (rank : 2144)
Query Neighborhood Hits	2923	Target Neighborhood Hits	19	Shared Neighborhood Hits	18
SwissProt Accessions	Q7TSA3	Gene names	Btla
Domain Architecture	No domain graphic available
Description	B- and T-lymphocyte attenuator precursor (B- and T-lymphocyte- associated protein) (CD272 antigen).

CAC1H_MOUSE
θ value	5.27518 (rank : 2394)	NC score	-0.000111 (rank : 2844)
Query Neighborhood Hits	2923	Target Neighborhood Hits	230	Shared Neighborhood Hits	66
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

CCNB1_HUMAN
θ value	5.27518 (rank : 2395)	NC score	0.001689 (rank : 2771)
Query Neighborhood Hits	2923	Target Neighborhood Hits	61	Shared Neighborhood Hits	22
SwissProt Accessions	P14635	Gene names	CCNB1, CCNB
Domain Architecture
Description	G2/mitotic-specific cyclin-B1.

CD1D2_MOUSE
θ value	5.27518 (rank : 2396)	NC score	-0.006993 (rank : 3008)
Query Neighborhood Hits	2923	Target Neighborhood Hits	190	Shared Neighborhood Hits	50
SwissProt Accessions	P11610	Gene names	Cd1d2, Cd1.2
Domain Architecture
Description	T-cell surface glycoprotein CD1d2 precursor (CD1.2 antigen).

CD45_MOUSE
θ value	5.27518 (rank : 2397)	NC score	0.062976 (rank : 1374)
Query Neighborhood Hits	2923	Target Neighborhood Hits	178	Shared Neighborhood Hits	88
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

CHCH3_HUMAN
θ value	5.27518 (rank : 2398)	NC score	0.037236 (rank : 1886)
Query Neighborhood Hits	2923	Target Neighborhood Hits	222	Shared Neighborhood Hits	133
SwissProt Accessions	Q9NX63	Gene names	CHCHD3
Domain Architecture	No domain graphic available
Description	Coiled-coil-helix-coiled-coil-helix domain-containing protein 3.

CHSTB_HUMAN
θ value	5.27518 (rank : 2399)	NC score	-0.001638 (rank : 2900)
Query Neighborhood Hits	2923	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NPF2, Q9NXY6, Q9NY36	Gene names	CHST11
Domain Architecture	No domain graphic available
Description	Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O- sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4ST) (C4ST-1) (C4S-1).

CLCN2_MOUSE
θ value	5.27518 (rank : 2400)	NC score	-0.003061 (rank : 2935)
Query Neighborhood Hits	2923	Target Neighborhood Hits	34	Shared Neighborhood Hits	7
SwissProt Accessions	Q9R0A1, Q9WUJ9	Gene names	Clcn2, Clc2
Domain Architecture
Description	Chloride channel protein 2 (ClC-2).

CND3_HUMAN
θ value	5.27518 (rank : 2401)	NC score	0.006661 (rank : 2583)
Query Neighborhood Hits	2923	Target Neighborhood Hits	74	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BPX3, Q96SV9, Q9BUR3, Q9BVY1, Q9H914, Q9H9Z6, Q9HBI9	Gene names	NCAPG, CAPG, NYMEL3
Domain Architecture
Description	Condensin complex subunit 3 (Non-SMC condensin I complex subunit G) (Chromosome-associated protein G) (Condensin subunit CAP-G) (hCAP-G) (XCAP-G homolog) (Antigen NY-MEL-3).

CO002_HUMAN
θ value	5.27518 (rank : 2402)	NC score	0.029783 (rank : 2008)
Query Neighborhood Hits	2923	Target Neighborhood Hits	387	Shared Neighborhood Hits	140
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

CT116_HUMAN
θ value	5.27518 (rank : 2403)	NC score	0.038989 (rank : 1857)
Query Neighborhood Hits	2923	Target Neighborhood Hits	294	Shared Neighborhood Hits	174
SwissProt Accessions	Q96HY6, Q9BW47	Gene names	C20orf116
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf116 precursor.

CTGE5_HUMAN
θ value	5.27518 (rank : 2404)	NC score	0.044964 (rank : 1767)
Query Neighborhood Hits	2923	Target Neighborhood Hits	800	Shared Neighborhood Hits	348
SwissProt Accessions	O15320, O00169, Q6P2R8, Q8IX92, Q8IX93	Gene names	CTAGE5, MEA11, MEA6, MGEA11, MGEA6
Domain Architecture
Description	Cutaneous T-cell lymphoma-associated antigen 5 (cTAGE-5 protein) (cTAGE family member 5) (Meningioma-expressed antigen 6/11).

DCBD2_HUMAN
θ value	5.27518 (rank : 2405)	NC score	-0.002358 (rank : 2916)
Query Neighborhood Hits	2923	Target Neighborhood Hits	118	Shared Neighborhood Hits	13
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

DDX21_HUMAN
θ value	5.27518 (rank : 2406)	NC score	-0.000422 (rank : 2854)
Query Neighborhood Hits	2923	Target Neighborhood Hits	308	Shared Neighborhood Hits	133
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DESM_HUMAN
θ value	5.27518 (rank : 2407)	NC score	0.015636 (rank : 2299)
Query Neighborhood Hits	2923	Target Neighborhood Hits	495	Shared Neighborhood Hits	222
SwissProt Accessions	P17661, Q15787, Q8IZR1, Q8IZR6, Q8NES2, Q8NEU6, Q8TAC4, Q8TCX2, Q8TD99, Q9UHN5, Q9UJ80	Gene names	DES
Domain Architecture
Description	Desmin.

DICER_HUMAN
θ value	5.27518 (rank : 2408)	NC score	-0.003088 (rank : 2936)
Query Neighborhood Hits	2923	Target Neighborhood Hits	126	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UPY3, O95943, Q9UQ02	Gene names	DICER1, DICER, HERNA, KIAA0928
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Helicase with RNase motif) (Helicase-MOI).

DMD_MOUSE
θ value	5.27518 (rank : 2409)	NC score	0.043472 (rank : 1785)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1111	Shared Neighborhood Hits	410
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

DNJC8_HUMAN
θ value	5.27518 (rank : 2410)	NC score	0.017585 (rank : 2249)
Query Neighborhood Hits	2923	Target Neighborhood Hits	380	Shared Neighborhood Hits	173
SwissProt Accessions	O75937, Q6IBA4, Q8N4Z5, Q9P051, Q9P067	Gene names	DNAJC8, SPF31
Domain Architecture
Description	DnaJ homolog subfamily C member 8 (Splicing protein spf31).

DNJC8_MOUSE
θ value	5.27518 (rank : 2411)	NC score	0.019299 (rank : 2218)
Query Neighborhood Hits	2923	Target Neighborhood Hits	392	Shared Neighborhood Hits	182
SwissProt Accessions	Q6NZB0, Q6PG72, Q8C2M6	Gene names	Dnajc8
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 8.

DONS_HUMAN
θ value	5.27518 (rank : 2412)	NC score	0.003225 (rank : 2719)
Query Neighborhood Hits	2923	Target Neighborhood Hits	16	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NYP3, Q9NSR9, Q9NVZ5, Q9NYP1, Q9NYP2	Gene names	DONSON, C21orf60
Domain Architecture	No domain graphic available
Description	Protein downstream neighbor of Son (B17).

DREB_MOUSE
θ value	5.27518 (rank : 2413)	NC score	0.052239 (rank : 1657)
Query Neighborhood Hits	2923	Target Neighborhood Hits	446	Shared Neighborhood Hits	249
SwissProt Accessions	Q9QXS6, Q922X1, Q9QXS5	Gene names	Dbn1, Drba
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

DRP2_HUMAN
θ value	5.27518 (rank : 2414)	NC score	0.010924 (rank : 2447)
Query Neighborhood Hits	2923	Target Neighborhood Hits	186	Shared Neighborhood Hits	91
SwissProt Accessions	Q13474	Gene names	DRP2
Domain Architecture
Description	Dystrophin-related protein 2.

DYN2_HUMAN
θ value	5.27518 (rank : 2415)	NC score	0.004981 (rank : 2635)
Query Neighborhood Hits	2923	Target Neighborhood Hits	112	Shared Neighborhood Hits	47
SwissProt Accessions	P50570, Q7Z5S3, Q9UPH4	Gene names	DNM2, DYN2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5).

DYXC1_MOUSE
θ value	5.27518 (rank : 2416)	NC score	0.001427 (rank : 2784)
Query Neighborhood Hits	2923	Target Neighborhood Hits	172	Shared Neighborhood Hits	73
SwissProt Accessions	Q8R368	Gene names	Dyx1c1, Ekn1
Domain Architecture
Description	Dyslexia susceptibility 1 candidate gene 1 protein homolog.

EMAL4_HUMAN
θ value	5.27518 (rank : 2417)	NC score	-0.005919 (rank : 2993)
Query Neighborhood Hits	2923	Target Neighborhood Hits	306	Shared Neighborhood Hits	51
SwissProt Accessions	Q9HC35	Gene names	EML4, C2orf2, EMAPL4
Domain Architecture
Description	Echinoderm microtubule-associated protein-like 4 (EMAP-4) (Restrictedly overexpressed proliferation-associated protein) (Ropp 120).

EMIL2_MOUSE
θ value	5.27518 (rank : 2418)	NC score	0.028510 (rank : 2033)
Query Neighborhood Hits	2923	Target Neighborhood Hits	485	Shared Neighborhood Hits	226
SwissProt Accessions	Q8K482	Gene names	Emilin2
Domain Architecture
Description	EMILIN-2 precursor (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Basilin).

ENKUR_MOUSE
θ value	5.27518 (rank : 2419)	NC score	0.010650 (rank : 2451)
Query Neighborhood Hits	2923	Target Neighborhood Hits	51	Shared Neighborhood Hits	30
SwissProt Accessions	Q6SP97	Gene names
Domain Architecture	No domain graphic available
Description	Enkurin.

EZRI_MOUSE
θ value	5.27518 (rank : 2420)	NC score	0.040201 (rank : 1843)
Query Neighborhood Hits	2923	Target Neighborhood Hits	693	Shared Neighborhood Hits	313
SwissProt Accessions	P26040, Q80ZT8, Q9DCI1	Gene names	Vil2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

FMNL_HUMAN
θ value	5.27518 (rank : 2421)	NC score	0.037163 (rank : 1887)
Query Neighborhood Hits	2923	Target Neighborhood Hits	529	Shared Neighborhood Hits	285
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

FOLH1_MOUSE
θ value	5.27518 (rank : 2422)	NC score	-0.001853 (rank : 2905)
Query Neighborhood Hits	2923	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	O35409, Q9DCC2	Gene names	Folh1, Mopsm, Naalad1
Domain Architecture
Description	Glutamate carboxypeptidase 2 (EC 3.4.17.21) (Glutamate carboxypeptidase II) (Membrane glutamate carboxypeptidase) (mGCP) (N- acetylated-alpha-linked acidic dipeptidase I) (NAALADase I) (Pteroylpoly-gamma-glutamate carboxypeptidase) (Folylpoly-gamma- glutamate carboxypeptidase) (FGCP) (Folate hydrolase 1) (Prostate- specific membrane antigen homolog).

FREA_HUMAN
θ value	5.27518 (rank : 2423)	NC score	-0.006363 (rank : 2999)
Query Neighborhood Hits	2923	Target Neighborhood Hits	205	Shared Neighborhood Hits	48
SwissProt Accessions	O43638, Q96D28	Gene names	FKHL18, FREAC10
Domain Architecture	No domain graphic available
Description	Forkhead-related transcription factor 10 (FREAC-10) (Forkhead-like 18 protein).

FREM2_MOUSE
θ value	5.27518 (rank : 2424)	NC score	-0.000988 (rank : 2879)
Query Neighborhood Hits	2923	Target Neighborhood Hits	73	Shared Neighborhood Hits	20
SwissProt Accessions	Q6NVD0, Q4W2Q5, Q5H8C0, Q811G9, Q8C4G5, Q8CD46	Gene names	Frem2, Nv1
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 2 precursor (ECM3 homolog) (NV domain-containing protein 1).

GAB1_MOUSE
θ value	5.27518 (rank : 2425)	NC score	0.011036 (rank : 2441)
Query Neighborhood Hits	2923	Target Neighborhood Hits	233	Shared Neighborhood Hits	76
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

GASP1_MOUSE
θ value	5.27518 (rank : 2426)	NC score	0.006221 (rank : 2596)
Query Neighborhood Hits	2923	Target Neighborhood Hits	169	Shared Neighborhood Hits	69
SwissProt Accessions	Q5U4C1, Q8BKR8, Q8BUN4, Q8BYK9, Q8CHF4, Q8R095	Gene names	Gprasp1, Kiaa0443
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor-associated sorting protein 1 (GASP-1).

GDE_HUMAN
θ value	5.27518 (rank : 2427)	NC score	0.005473 (rank : 2611)
Query Neighborhood Hits	2923	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	P35573, P78354, P78544, Q9UF08	Gene names	AGL, GDE
Domain Architecture
Description	Glycogen debranching enzyme (Glycogen debrancher) [Includes: 4-alpha- glucanotransferase (EC 2.4.1.25) (Oligo-1,4-1,4-glucantransferase); Amylo-alpha-1,6-glucosidase (EC 3.2.1.33) (Amylo-1,6-glucosidase) (Dextrin 6-alpha-D-glucosidase)].

GEMI5_MOUSE
θ value	5.27518 (rank : 2428)	NC score	-0.009624 (rank : 3054)
Query Neighborhood Hits	2923	Target Neighborhood Hits	424	Shared Neighborhood Hits	75
SwissProt Accessions	Q8BX17	Gene names	Gemin5
Domain Architecture
Description	Gem-associated protein 5 (Gemin5).

GLIS3_MOUSE
θ value	5.27518 (rank : 2429)	NC score	-0.026840 (rank : 3094)
Query Neighborhood Hits	2923	Target Neighborhood Hits	861	Shared Neighborhood Hits	116
SwissProt Accessions	Q6XP49, Q8BI60	Gene names	Glis3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS3 (GLI-similar 3).

GNA14_HUMAN
θ value	5.27518 (rank : 2430)	NC score	-0.006503 (rank : 3002)
Query Neighborhood Hits	2923	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	O95837	Gene names	GNA14
Domain Architecture
Description	Guanine nucleotide-binding protein alpha-14 subunit (G-protein alpha subunit 14).

GOG8A_HUMAN
θ value	5.27518 (rank : 2431)	NC score	0.053075 (rank : 1636)
Query Neighborhood Hits	2923	Target Neighborhood Hits	635	Shared Neighborhood Hits	298
SwissProt Accessions	Q9NZW0, O94937, Q9NZG8, Q9NZW3	Gene names	GOLGA8A, KIAA0855
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 8A/B (Golgi autoantigen golgin-67) (88 kDa Golgi protein) (Gm88 autoantigen).

GOGA2_HUMAN
θ value	5.27518 (rank : 2432)	NC score	0.049499 (rank : 1713)
Query Neighborhood Hits	2923	Target Neighborhood Hits	856	Shared Neighborhood Hits	333
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

GRIPE_MOUSE
θ value	5.27518 (rank : 2433)	NC score	0.002463 (rank : 2746)
Query Neighborhood Hits	2923	Target Neighborhood Hits	70	Shared Neighborhood Hits	25
SwissProt Accessions	Q6GYP7, Q6GYP6, Q6ZQ28, Q8BNJ5, Q8C9G8, Q8CIW4, Q9JMC4	Gene names	Garnl1, Kiaa0884, Tulip1
Domain Architecture	No domain graphic available
Description	GTPase-activating RapGAP domain-like 1 (GAP-related-interacting partner to E12) (GRIPE) (Tuberin-like protein 1).

H12_MOUSE
θ value	5.27518 (rank : 2434)	NC score	0.012850 (rank : 2388)
Query Neighborhood Hits	2923	Target Neighborhood Hits	52	Shared Neighborhood Hits	30
SwissProt Accessions	P15864	Gene names	Hist1h1c, H1f2
Domain Architecture
Description	Histone H1.2 (H1 VAR.1) (H1c).

HA2B_MOUSE
θ value	5.27518 (rank : 2435)	NC score	-0.000879 (rank : 2874)
Query Neighborhood Hits	2923	Target Neighborhood Hits	199	Shared Neighborhood Hits	46
SwissProt Accessions	P14434, O78195	Gene names	H2-Aa
Domain Architecture
Description	H-2 class II histocompatibility antigen, A-B alpha chain precursor (IAalpha).

HA2K_MOUSE
θ value	5.27518 (rank : 2436)	NC score	-0.001155 (rank : 2884)
Query Neighborhood Hits	2923	Target Neighborhood Hits	199	Shared Neighborhood Hits	46
SwissProt Accessions	P01910	Gene names	H2-Aa
Domain Architecture
Description	H-2 class II histocompatibility antigen, A-K alpha chain precursor.

HB2B_HUMAN
θ value	5.27518 (rank : 2437)	NC score	0.001991 (rank : 2763)
Query Neighborhood Hits	2923	Target Neighborhood Hits	209	Shared Neighborhood Hits	57
SwissProt Accessions	P01912	Gene names
Domain Architecture
Description	HLA class II histocompatibility antigen, DR-1 beta chain precursor (Clone P2-beta-3).

HRBL_HUMAN
θ value	5.27518 (rank : 2438)	NC score	0.003574 (rank : 2706)
Query Neighborhood Hits	2923	Target Neighborhood Hits	179	Shared Neighborhood Hits	48
SwissProt Accessions	O95081, O75429, Q96AB9, Q96GL4	Gene names	HRBL, RABR
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

HV05_MOUSE
θ value	5.27518 (rank : 2439)	NC score	-0.012836 (rank : 3065)
Query Neighborhood Hits	2923	Target Neighborhood Hits	256	Shared Neighborhood Hits	51
SwissProt Accessions	P01749	Gene names	Igh-VJ558
Domain Architecture
Description	Ig heavy chain V region 3 precursor.

HV3K_HUMAN
θ value	5.27518 (rank : 2440)	NC score	-0.011837 (rank : 3063)
Query Neighborhood Hits	2923	Target Neighborhood Hits	185	Shared Neighborhood Hits	31
SwissProt Accessions	P01772	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V-III region KOL.

ICAM2_HUMAN
θ value	5.27518 (rank : 2441)	NC score	0.033501 (rank : 1959)
Query Neighborhood Hits	2923	Target Neighborhood Hits	21	Shared Neighborhood Hits	13
SwissProt Accessions	P13598, Q14600	Gene names	ICAM2
Domain Architecture
Description	Intercellular adhesion molecule 2 precursor (ICAM-2) (CD102 antigen).

IF2P_HUMAN
θ value	5.27518 (rank : 2442)	NC score	0.065750 (rank : 1339)
Query Neighborhood Hits	2923	Target Neighborhood Hits	889	Shared Neighborhood Hits	381
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

IF4G3_HUMAN
θ value	5.27518 (rank : 2443)	NC score	0.016367 (rank : 2282)
Query Neighborhood Hits	2923	Target Neighborhood Hits	247	Shared Neighborhood Hits	119
SwissProt Accessions	O43432, Q15597, Q8NEN1	Gene names	EIF4G3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

JHD3B_MOUSE
θ value	5.27518 (rank : 2444)	NC score	0.010425 (rank : 2459)
Query Neighborhood Hits	2923	Target Neighborhood Hits	152	Shared Neighborhood Hits	72
SwissProt Accessions	Q91VY5, Q3UR22, Q6ZQ30, Q99K42	Gene names	Jmjd2b, Jhdm3b
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

K6PP_HUMAN
θ value	5.27518 (rank : 2445)	NC score	-0.000816 (rank : 2872)
Query Neighborhood Hits	2923	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q01813	Gene names	PFKP, PFKF
Domain Architecture
Description	6-phosphofructokinase type C (EC 2.7.1.11) (Phosphofructokinase 1) (Phosphohexokinase) (Phosphofructo-1-kinase isozyme C) (PFK-C) (6- phosphofructokinase, platelet type).

KLF8_HUMAN
θ value	5.27518 (rank : 2446)	NC score	-0.029598 (rank : 3111)
Query Neighborhood Hits	2923	Target Neighborhood Hits	704	Shared Neighborhood Hits	65
SwissProt Accessions	O95600, Q59GV5, Q5HYQ5, Q5JXP7, Q6MZJ7, Q9UGC4	Gene names	KLF8, BKLF3, ZNF741
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 8 (Basic krueppel-like factor 3) (Zinc finger protein 741).

KTNB1_MOUSE
θ value	5.27518 (rank : 2447)	NC score	-0.017993 (rank : 3079)
Query Neighborhood Hits	2923	Target Neighborhood Hits	356	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BG40, Q8CD18, Q8R1J0, Q9CWV2	Gene names	Katnb1
Domain Architecture	No domain graphic available
Description	Katanin p80 WD40-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin).

KV1F_HUMAN
θ value	5.27518 (rank : 2448)	NC score	-0.001843 (rank : 2904)
Query Neighborhood Hits	2923	Target Neighborhood Hits	261	Shared Neighborhood Hits	78
SwissProt Accessions	P01598	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-I region EU.

KV5A_MOUSE
θ value	5.27518 (rank : 2449)	NC score	-0.005188 (rank : 2979)
Query Neighborhood Hits	2923	Target Neighborhood Hits	233	Shared Neighborhood Hits	63
SwissProt Accessions	P01633	Gene names
Domain Architecture
Description	Ig kappa chain V-V region MPC11 precursor.

KV5E_MOUSE
θ value	5.27518 (rank : 2450)	NC score	0.000865 (rank : 2811)
Query Neighborhood Hits	2923	Target Neighborhood Hits	249	Shared Neighborhood Hits	89
SwissProt Accessions	P01637	Gene names
Domain Architecture
Description	Ig kappa chain V-V region T1 precursor.

KV5Q_MOUSE
θ value	5.27518 (rank : 2451)	NC score	-0.004670 (rank : 2968)
Query Neighborhood Hits	2923	Target Neighborhood Hits	242	Shared Neighborhood Hits	68
SwissProt Accessions	P01650	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-V region UPC 61.

KV6H_MOUSE
θ value	5.27518 (rank : 2452)	NC score	-0.002779 (rank : 2929)
Query Neighborhood Hits	2923	Target Neighborhood Hits	279	Shared Neighborhood Hits	79
SwissProt Accessions	P04942	Gene names
Domain Architecture
Description	Ig kappa chain V-VI region NQ5-61.1.2.

LIPB2_MOUSE
θ value	5.27518 (rank : 2453)	NC score	0.034507 (rank : 1941)
Query Neighborhood Hits	2923	Target Neighborhood Hits	570	Shared Neighborhood Hits	253
SwissProt Accessions	O35711, Q7TMG4, Q8CBS6, Q99KX6	Gene names	Ppfibp2, Cclp1
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2) (Coiled-coil-like protein 1).

LRC50_HUMAN
θ value	5.27518 (rank : 2454)	NC score	0.015274 (rank : 2312)
Query Neighborhood Hits	2923	Target Neighborhood Hits	275	Shared Neighborhood Hits	76
SwissProt Accessions	Q8NEP3, Q69YI8, Q69YJ0, Q96LP3	Gene names	LRRC50
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 50.

LV1H_HUMAN
θ value	5.27518 (rank : 2455)	NC score	-0.006060 (rank : 2996)
Query Neighborhood Hits	2923	Target Neighborhood Hits	255	Shared Neighborhood Hits	60
SwissProt Accessions	P06887	Gene names
Domain Architecture	No domain graphic available
Description	Ig lambda chain V-I region MEM.

LV2F_HUMAN
θ value	5.27518 (rank : 2456)	NC score	-0.005490 (rank : 2984)
Query Neighborhood Hits	2923	Target Neighborhood Hits	253	Shared Neighborhood Hits	63
SwissProt Accessions	P01709	Gene names
Domain Architecture	No domain graphic available
Description	Ig lambda chain V-II region MGC.

LYPD3_HUMAN
θ value	5.27518 (rank : 2457)	NC score	0.004354 (rank : 2667)
Query Neighborhood Hits	2923	Target Neighborhood Hits	43	Shared Neighborhood Hits	15
SwissProt Accessions	O95274, Q9UJ74	Gene names	LYPD3, C4.4A
Domain Architecture	No domain graphic available
Description	Ly6/PLAUR domain-containing protein 3 precursor (GPI-anchored metastasis-associated protein C4.4A homolog) (Matrigel-induced gene C4 protein) (MIG-C4).

MAGC3_HUMAN
θ value	5.27518 (rank : 2458)	NC score	-0.000657 (rank : 2866)
Query Neighborhood Hits	2923	Target Neighborhood Hits	71	Shared Neighborhood Hits	23
SwissProt Accessions	Q8TD91, Q5JZ43, Q9BZ80	Gene names	MAGEC3, HCA2
Domain Architecture
Description	Melanoma-associated antigen C3 (MAGE-C3 antigen) (Hepatocellular carcinoma-associated antigen 2).

MAP9_HUMAN
θ value	5.27518 (rank : 2459)	NC score	0.046609 (rank : 1744)
Query Neighborhood Hits	2923	Target Neighborhood Hits	518	Shared Neighborhood Hits	261
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

MAVS_MOUSE
θ value	5.27518 (rank : 2460)	NC score	0.020153 (rank : 2201)
Query Neighborhood Hits	2923	Target Neighborhood Hits	170	Shared Neighborhood Hits	74
SwissProt Accessions	Q8VCF0	Gene names	Mavs, Ips1, Visa
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif).

MBIP1_HUMAN
θ value	5.27518 (rank : 2461)	NC score	0.006613 (rank : 2586)
Query Neighborhood Hits	2923	Target Neighborhood Hits	27	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NS73, Q86TZ2, Q96AS5, Q9BS93, Q9NZE1	Gene names	MBIP
Domain Architecture	No domain graphic available
Description	MAP3K12-binding inhibitory protein 1 (MAPK upstream kinase-binding inhibitory protein) (MUK-binding inhibitory protein).

MD2BP_MOUSE
θ value	5.27518 (rank : 2462)	NC score	0.003718 (rank : 2694)
Query Neighborhood Hits	2923	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	Q9DCX1, Q99J05, Q9D0Y3	Gene names	Mad2l1bp, Mad2lbp
Domain Architecture
Description	MAD2L1-binding protein.

MDM4_MOUSE
θ value	5.27518 (rank : 2463)	NC score	0.001178 (rank : 2795)
Query Neighborhood Hits	2923	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	O35618	Gene names	Mdm4, Mdmx
Domain Architecture
Description	Mdm4 protein (p53-binding protein Mdm4) (Mdm2-like p53-binding protein) (Mdmx protein) (Double minute 4 protein).

MGP_MOUSE
θ value	5.27518 (rank : 2464)	NC score	0.007174 (rank : 2564)
Query Neighborhood Hits	2923	Target Neighborhood Hits	3	Shared Neighborhood Hits	3
SwissProt Accessions	P19788, Q8JZW0	Gene names	Mgp, Mglap
Domain Architecture
Description	Matrix Gla-protein precursor (MGP).

MICA1_MOUSE
θ value	5.27518 (rank : 2465)	NC score	0.015661 (rank : 2296)
Query Neighborhood Hits	2923	Target Neighborhood Hits	400	Shared Neighborhood Hits	187
SwissProt Accessions	Q8VDP3	Gene names	Mical1, Mical, Nical
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

MNDA_HUMAN
θ value	5.27518 (rank : 2466)	NC score	0.006999 (rank : 2572)
Query Neighborhood Hits	2923	Target Neighborhood Hits	76	Shared Neighborhood Hits	47
SwissProt Accessions	P41218	Gene names	MNDA
Domain Architecture
Description	Myeloid cell nuclear differentiation antigen.

NEST_HUMAN
θ value	5.27518 (rank : 2467)	NC score	0.059426 (rank : 1459)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1305	Shared Neighborhood Hits	495
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

NFAT5_MOUSE
θ value	5.27518 (rank : 2468)	NC score	0.004495 (rank : 2661)
Query Neighborhood Hits	2923	Target Neighborhood Hits	162	Shared Neighborhood Hits	60
SwissProt Accessions	Q9WV30	Gene names	Nfat5
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T cell transcription factor NFAT5) (NF-AT5) (Rel domain-containing transcription factor NFAT5).

NUCB2_MOUSE
θ value	5.27518 (rank : 2469)	NC score	0.031144 (rank : 1994)
Query Neighborhood Hits	2923	Target Neighborhood Hits	459	Shared Neighborhood Hits	224
SwissProt Accessions	P81117	Gene names	Nucb2, Nefa
Domain Architecture	No domain graphic available
Description	Nucleobindin-2 precursor (DNA-binding protein NEFA).

OPTN_MOUSE
θ value	5.27518 (rank : 2470)	NC score	0.059290 (rank : 1462)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1120	Shared Neighborhood Hits	436
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

PAP2_HUMAN
θ value	5.27518 (rank : 2471)	NC score	-0.002290 (rank : 2912)
Query Neighborhood Hits	2923	Target Neighborhood Hits	106	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BXP8, Q96PH7, Q96PH8, Q9H4C9	Gene names	PAPPA2
Domain Architecture	No domain graphic available
Description	Pappalysin-2 precursor (EC 3.4.24.-) (Pregnancy-associated plasma protein-A2) (PAPP-A2) (Pregnancy-associated plasma protein-E1) (PAPP- E).

PCD16_HUMAN
θ value	5.27518 (rank : 2472)	NC score	-0.006744 (rank : 3006)
Query Neighborhood Hits	2923	Target Neighborhood Hits	245	Shared Neighborhood Hits	75
SwissProt Accessions	Q96JQ0, O15098	Gene names	DCHS1, CDH19, FIB1, KIAA1773, PCDH16
Domain Architecture
Description	Protocadherin-16 precursor (Dachsous 1) (Cadherin-19) (Fibroblast cadherin 1).

PCDA1_HUMAN
θ value	5.27518 (rank : 2473)	NC score	-0.007391 (rank : 3016)
Query Neighborhood Hits	2923	Target Neighborhood Hits	199	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y5I3, O75288, Q9NRT7	Gene names	PCDHA1
Domain Architecture
Description	Protocadherin alpha 1 precursor (PCDH-alpha1).

PCDA2_HUMAN
θ value	5.27518 (rank : 2474)	NC score	-0.007645 (rank : 3025)
Query Neighborhood Hits	2923	Target Neighborhood Hits	192	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y5H9, O75287, Q9BTV3	Gene names	PCDHA2
Domain Architecture
Description	Protocadherin alpha 2 precursor (PCDH-alpha2).

PCDA3_HUMAN
θ value	5.27518 (rank : 2475)	NC score	-0.007450 (rank : 3018)
Query Neighborhood Hits	2923	Target Neighborhood Hits	203	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y5H8, O75286	Gene names	PCDHA3
Domain Architecture
Description	Protocadherin alpha 3 precursor (PCDH-alpha3).

PCDA4_HUMAN
θ value	5.27518 (rank : 2476)	NC score	-0.007366 (rank : 3014)
Query Neighborhood Hits	2923	Target Neighborhood Hits	193	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UN74, O75285	Gene names	PCDHA4
Domain Architecture
Description	Protocadherin alpha 4 precursor (PCDH-alpha4).

PCDA4_MOUSE
θ value	5.27518 (rank : 2477)	NC score	-0.007385 (rank : 3015)
Query Neighborhood Hits	2923	Target Neighborhood Hits	193	Shared Neighborhood Hits	46
SwissProt Accessions	O88689, Q3UEX3, Q6PAM9, Q8K487, Q8K489	Gene names	Pcdha4, Cnr1
Domain Architecture	No domain graphic available
Description	Protocadherin alpha 4 precursor (PCDH-alpha4).

PCDA6_HUMAN
θ value	5.27518 (rank : 2478)	NC score	-0.007744 (rank : 3027)
Query Neighborhood Hits	2923	Target Neighborhood Hits	187	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UN73, O75283, Q9NRT8	Gene names	PCDHA6
Domain Architecture
Description	Protocadherin alpha 6 precursor (PCDH-alpha6).

PCDA7_HUMAN
θ value	5.27518 (rank : 2479)	NC score	-0.007391 (rank : 3017)
Query Neighborhood Hits	2923	Target Neighborhood Hits	221	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UN72, O75282	Gene names	PCDHA7
Domain Architecture
Description	Protocadherin alpha 7 precursor (PCDH-alpha7).

PCDA8_HUMAN
θ value	5.27518 (rank : 2480)	NC score	-0.007569 (rank : 3024)
Query Neighborhood Hits	2923	Target Neighborhood Hits	187	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y5H6, O75281	Gene names	PCDHA8
Domain Architecture
Description	Protocadherin alpha 8 precursor (PCDH-alpha8).

PCDA9_HUMAN
θ value	5.27518 (rank : 2481)	NC score	-0.007708 (rank : 3026)
Query Neighborhood Hits	2923	Target Neighborhood Hits	203	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y5H5, O15053	Gene names	PCDHA9, KIAA0345
Domain Architecture
Description	Protocadherin alpha 9 precursor (PCDH-alpha9).

PCDAA_HUMAN
θ value	5.27518 (rank : 2482)	NC score	-0.007451 (rank : 3019)
Query Neighborhood Hits	2923	Target Neighborhood Hits	183	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y5I2, O75280, Q9NRU2	Gene names	PCDHA10
Domain Architecture
Description	Protocadherin alpha 10 precursor (PCDH-alpha10).

PCDAB_HUMAN
θ value	5.27518 (rank : 2483)	NC score	-0.007467 (rank : 3020)
Query Neighborhood Hits	2923	Target Neighborhood Hits	211	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y5I1, O75279	Gene names	PCDHA11
Domain Architecture
Description	Protocadherin alpha 11 precursor (PCDH-alpha11).

PCDAC_HUMAN
θ value	5.27518 (rank : 2484)	NC score	-0.007269 (rank : 3010)
Query Neighborhood Hits	2923	Target Neighborhood Hits	200	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UN75, O75278	Gene names	PCDHA12
Domain Architecture
Description	Protocadherin alpha 12 precursor (PCDH-alpha12).

PCDAD_HUMAN
θ value	5.27518 (rank : 2485)	NC score	-0.007551 (rank : 3022)
Query Neighborhood Hits	2923	Target Neighborhood Hits	197	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y5I0, O75277	Gene names	PCDHA13
Domain Architecture
Description	Protocadherin alpha 13 precursor (PCDH-alpha13).

PCDC1_HUMAN
θ value	5.27518 (rank : 2486)	NC score	-0.008315 (rank : 3035)
Query Neighborhood Hits	2923	Target Neighborhood Hits	181	Shared Neighborhood Hits	41
SwissProt Accessions	Q9H158, Q9Y5F5, Q9Y5I5	Gene names	PCDHAC1
Domain Architecture
Description	Protocadherin alpha C1 precursor (PCDH-alpha-C1).

PDCD2_MOUSE
θ value	5.27518 (rank : 2487)	NC score	0.003705 (rank : 2695)
Query Neighborhood Hits	2923	Target Neighborhood Hits	29	Shared Neighborhood Hits	5
SwissProt Accessions	P46718, Q8BR06	Gene names	Pdcd2, Rp8
Domain Architecture
Description	Programmed cell death protein 2 (Zinc finger protein Rp-8).

PDE6C_MOUSE
θ value	5.27518 (rank : 2488)	NC score	-0.005571 (rank : 2986)
Query Neighborhood Hits	2923	Target Neighborhood Hits	45	Shared Neighborhood Hits	6
SwissProt Accessions	Q91ZQ1, Q8R0D4	Gene names	Pde6c
Domain Architecture	No domain graphic available
Description	Cone cGMP-specific 3',5'-cyclic phosphodiesterase alpha'-subunit (EC 3.1.4.35) (cGMP phosphodiesterase 6C).

PDIA1_MOUSE
θ value	5.27518 (rank : 2489)	NC score	0.000298 (rank : 2831)
Query Neighborhood Hits	2923	Target Neighborhood Hits	50	Shared Neighborhood Hits	8
SwissProt Accessions	P09103	Gene names	P4hb, Pdia1
Domain Architecture
Description	Protein disulfide-isomerase precursor (EC 5.3.4.1) (PDI) (Prolyl 4- hydroxylase subunit beta) (Cellular thyroid hormone-binding protein) (p55) (Erp59).

PDIA4_MOUSE
θ value	5.27518 (rank : 2490)	NC score	-0.000178 (rank : 2846)
Query Neighborhood Hits	2923	Target Neighborhood Hits	57	Shared Neighborhood Hits	9
SwissProt Accessions	P08003, P15841	Gene names	Pdia4, Cai, Erp72
Domain Architecture
Description	Protein disulfide-isomerase A4 precursor (EC 5.3.4.1) (Protein ERp-72) (ERp72).

PECR_MOUSE
θ value	5.27518 (rank : 2491)	NC score	-0.005303 (rank : 2980)
Query Neighborhood Hits	2923	Target Neighborhood Hits	73	Shared Neighborhood Hits	5
SwissProt Accessions	Q99MZ7, Q9CX01, Q9JIF4	Gene names	Pecr
Domain Architecture	No domain graphic available
Description	Peroxisomal trans-2-enoyl-CoA reductase (EC 1.3.1.38).

PHF14_HUMAN
θ value	5.27518 (rank : 2492)	NC score	0.019026 (rank : 2219)
Query Neighborhood Hits	2923	Target Neighborhood Hits	447	Shared Neighborhood Hits	210
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

PHLPL_HUMAN
θ value	5.27518 (rank : 2493)	NC score	0.016583 (rank : 2276)
Query Neighborhood Hits	2923	Target Neighborhood Hits	310	Shared Neighborhood Hits	65
SwissProt Accessions	Q6ZVD8, Q9NV17, Q9Y2E3	Gene names	PHLPPL, KIAA0931
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat protein phosphatase-like (EC 3.1.3.16).

PLIN_HUMAN
θ value	5.27518 (rank : 2494)	NC score	0.004840 (rank : 2646)
Query Neighborhood Hits	2923	Target Neighborhood Hits	37	Shared Neighborhood Hits	14
SwissProt Accessions	O60240, Q8N5Y6	Gene names	PLIN
Domain Architecture
Description	Perilipin (PERI) (Lipid droplet-associated protein).

PTN13_MOUSE
θ value	5.27518 (rank : 2495)	NC score	0.033107 (rank : 1966)
Query Neighborhood Hits	2923	Target Neighborhood Hits	426	Shared Neighborhood Hits	133
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

RBM6_HUMAN
θ value	5.27518 (rank : 2496)	NC score	0.008503 (rank : 2524)
Query Neighborhood Hits	2923	Target Neighborhood Hits	221	Shared Neighborhood Hits	72
SwissProt Accessions	P78332, O60549, O75524	Gene names	RBM6, DEF3
Domain Architecture
Description	RNA-binding protein 6 (RNA-binding motif protein 6) (RNA-binding protein DEF-3) (Lung cancer antigen NY-LU-12) (Protein G16).

RBPMS_HUMAN
θ value	5.27518 (rank : 2497)	NC score	0.002584 (rank : 2739)
Query Neighborhood Hits	2923	Target Neighborhood Hits	43	Shared Neighborhood Hits	5
SwissProt Accessions	Q93062, Q92516, Q92517, Q92518, Q96J26	Gene names	RBPMS
Domain Architecture
Description	RNA-binding protein with multiple splicing (RBP-MS).

RB_MOUSE
θ value	5.27518 (rank : 2498)	NC score	0.002752 (rank : 2735)
Query Neighborhood Hits	2923	Target Neighborhood Hits	31	Shared Neighborhood Hits	10
SwissProt Accessions	P13405	Gene names	Rb1, Rb-1
Domain Architecture
Description	Retinoblastoma-associated protein (PP105) (RB).

RL4_HUMAN
θ value	5.27518 (rank : 2499)	NC score	0.009188 (rank : 2504)
Query Neighborhood Hits	2923	Target Neighborhood Hits	13	Shared Neighborhood Hits	7
SwissProt Accessions	P36578, P39029, Q4VBR0, Q969Z9	Gene names	RPL4, RPL1
Domain Architecture
Description	60S ribosomal protein L4 (L1).

RNF8_HUMAN
θ value	5.27518 (rank : 2500)	NC score	0.020614 (rank : 2190)
Query Neighborhood Hits	2923	Target Neighborhood Hits	622	Shared Neighborhood Hits	221
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

RPGR1_MOUSE
θ value	5.27518 (rank : 2501)	NC score	0.042452 (rank : 1805)
Query Neighborhood Hits	2923	Target Neighborhood Hits	713	Shared Neighborhood Hits	337
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

RT15_HUMAN
θ value	5.27518 (rank : 2502)	NC score	0.005485 (rank : 2610)
Query Neighborhood Hits	2923	Target Neighborhood Hits	27	Shared Neighborhood Hits	14
SwissProt Accessions	P82914, Q9H2K1	Gene names	MRPS15, RPMS15
Domain Architecture
Description	28S ribosomal protein S15, mitochondrial precursor (S15mt) (MRP-S15).

SC24A_MOUSE
θ value	5.27518 (rank : 2503)	NC score	0.014397 (rank : 2345)
Query Neighborhood Hits	2923	Target Neighborhood Hits	394	Shared Neighborhood Hits	137
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

SCAR3_HUMAN
θ value	5.27518 (rank : 2504)	NC score	0.010604 (rank : 2452)
Query Neighborhood Hits	2923	Target Neighborhood Hits	205	Shared Neighborhood Hits	90
SwissProt Accessions	Q6AZY7, Q9UM15, Q9UM16	Gene names	SCARA3, CSR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class A member 3 (Cellular stress response gene protein).

SCG2_HUMAN
θ value	5.27518 (rank : 2505)	NC score	0.018286 (rank : 2231)
Query Neighborhood Hits	2923	Target Neighborhood Hits	190	Shared Neighborhood Hits	94
SwissProt Accessions	P13521, Q8TBH3	Gene names	SCG2, CHGC
Domain Architecture
Description	Secretogranin-2 precursor (Secretogranin II) (SgII) (Chromogranin C) [Contains: Secretoneurin (SN)].

SEM3D_MOUSE
θ value	5.27518 (rank : 2506)	NC score	0.010301 (rank : 2461)
Query Neighborhood Hits	2923	Target Neighborhood Hits	97	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BH34	Gene names	Sema3d
Domain Architecture	No domain graphic available
Description	Semaphorin-3D precursor.

SEMG1_HUMAN
θ value	5.27518 (rank : 2507)	NC score	0.012144 (rank : 2410)
Query Neighborhood Hits	2923	Target Neighborhood Hits	200	Shared Neighborhood Hits	86
SwissProt Accessions	P04279, Q6X4I9, Q6Y809, Q6Y822, Q6Y823, Q86U64, Q96QM3	Gene names	SEMG1, SEMG
Domain Architecture
Description	Semenogelin-1 precursor (Semenogelin I) (SGI) [Contains: Alpha- inhibin-92; Alpha-inhibin-31; Seminal basic protein].

SEPT8_MOUSE
θ value	5.27518 (rank : 2508)	NC score	0.010365 (rank : 2460)
Query Neighborhood Hits	2923	Target Neighborhood Hits	251	Shared Neighborhood Hits	129
SwissProt Accessions	Q8CHH9, Q80YC7, Q9ESF7	Gene names	Sept8, Kiaa0202
Domain Architecture
Description	Septin-8.

SETB1_HUMAN
θ value	5.27518 (rank : 2509)	NC score	0.005102 (rank : 2632)
Query Neighborhood Hits	2923	Target Neighborhood Hits	141	Shared Neighborhood Hits	49
SwissProt Accessions	Q15047, Q96GM9	Gene names	SETDB1, KIAA0067
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

SF01_MOUSE
θ value	5.27518 (rank : 2510)	NC score	0.027693 (rank : 2053)
Query Neighborhood Hits	2923	Target Neighborhood Hits	240	Shared Neighborhood Hits	112
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

SFRIP_HUMAN
θ value	5.27518 (rank : 2511)	NC score	0.050030 (rank : 1704)
Query Neighborhood Hits	2923	Target Neighborhood Hits	530	Shared Neighborhood Hits	227
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

SGOL1_HUMAN
θ value	5.27518 (rank : 2512)	NC score	0.009953 (rank : 2473)
Query Neighborhood Hits	2923	Target Neighborhood Hits	62	Shared Neighborhood Hits	30
SwissProt Accessions	Q5FBB7, Q588H5, Q5FBB4, Q5FBB5, Q5FBB6, Q5FBB8, Q8N579, Q8WVL0, Q9BVA8, Q9H275	Gene names	SGOL1, SGO1
Domain Architecture	No domain graphic available
Description	Shugoshin-like 1 (hSgo1) (Serologically defined breast cancer antigen NY-BR-85).

SIL1_MOUSE
θ value	5.27518 (rank : 2513)	NC score	0.005008 (rank : 2634)
Query Neighborhood Hits	2923	Target Neighborhood Hits	68	Shared Neighborhood Hits	36
SwissProt Accessions	Q9EPK6, Q91V34	Gene names	Sil1
Domain Architecture	No domain graphic available
Description	Nucleotide exchange factor SIL1 precursor.

SLAF9_MOUSE
θ value	5.27518 (rank : 2514)	NC score	0.066440 (rank : 1332)
Query Neighborhood Hits	2923	Target Neighborhood Hits	78	Shared Neighborhood Hits	67
SwissProt Accessions	Q9D780, Q8BTK0, Q8VE93	Gene names	Slamf9
Domain Architecture	No domain graphic available
Description	SLAM family member 9 precursor.

SMBT2_MOUSE
θ value	5.27518 (rank : 2515)	NC score	-0.000701 (rank : 2867)
Query Neighborhood Hits	2923	Target Neighborhood Hits	47	Shared Neighborhood Hits	11
SwissProt Accessions	Q5DTW2, Q80VG7	Gene names	Sfmbt2, Kiaa1617
Domain Architecture	No domain graphic available
Description	Scm-like with four MBT domains protein 2.

SNUT3_MOUSE
θ value	5.27518 (rank : 2516)	NC score	0.013382 (rank : 2372)
Query Neighborhood Hits	2923	Target Neighborhood Hits	50	Shared Neighborhood Hits	26
SwissProt Accessions	Q8K194, Q8BRA8, Q9CSV0	Gene names
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 3.

SOX5_HUMAN
θ value	5.27518 (rank : 2517)	NC score	0.003099 (rank : 2723)
Query Neighborhood Hits	2923	Target Neighborhood Hits	219	Shared Neighborhood Hits	85
SwissProt Accessions	P35711, Q86UK8, Q8J017, Q8J018, Q8J019, Q8J020, Q8N1D9, Q8N7E0, Q8TEA4	Gene names	SOX5
Domain Architecture
Description	Transcription factor SOX-5.

SPAG7_HUMAN
θ value	5.27518 (rank : 2518)	NC score	0.008637 (rank : 2519)
Query Neighborhood Hits	2923	Target Neighborhood Hits	25	Shared Neighborhood Hits	17
SwissProt Accessions	O75391, Q96EU5	Gene names	SPAG7
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 7.

SRBP1_MOUSE
θ value	5.27518 (rank : 2519)	NC score	0.012207 (rank : 2408)
Query Neighborhood Hits	2923	Target Neighborhood Hits	384	Shared Neighborhood Hits	117
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

SRRM2_MOUSE
θ value	5.27518 (rank : 2520)	NC score	0.096375 (rank : 1217)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1470	Shared Neighborhood Hits	537
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

STMN1_MOUSE
θ value	5.27518 (rank : 2521)	NC score	0.042319 (rank : 1807)
Query Neighborhood Hits	2923	Target Neighborhood Hits	560	Shared Neighborhood Hits	289
SwissProt Accessions	P54227	Gene names	Stmn1, Lag, Lap18, Pr22
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Pr22 protein) (Leukemia-associated gene protein).

TATD2_HUMAN
θ value	5.27518 (rank : 2522)	NC score	0.010066 (rank : 2469)
Query Neighborhood Hits	2923	Target Neighborhood Hits	66	Shared Neighborhood Hits	32
SwissProt Accessions	Q93075	Gene names	TATDN2, KIAA0218
Domain Architecture	No domain graphic available
Description	TatD DNase domain-containing deoxyribonuclease 2 (EC 3.1.21.-).

TBX10_MOUSE
θ value	5.27518 (rank : 2523)	NC score	-0.004332 (rank : 2962)
Query Neighborhood Hits	2923	Target Neighborhood Hits	47	Shared Neighborhood Hits	7
SwissProt Accessions	Q810F8, O54841, Q6QH75	Gene names	Tbx10, Tbx13, Tbx7
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX10 (T-box protein 10) (T-box protein 13) (MmTBX7).

TCF17_HUMAN
θ value	5.27518 (rank : 2524)	NC score	-0.029209 (rank : 3108)
Query Neighborhood Hits	2923	Target Neighborhood Hits	797	Shared Neighborhood Hits	83
SwissProt Accessions	O60765, Q9UNJ8	Gene names	ZNF354A, EZNF, HKL1, TCF17
Domain Architecture
Description	Zinc finger protein 354A (Transcription factor 17) (Zinc finger protein eZNF).

TMF1_HUMAN
θ value	5.27518 (rank : 2525)	NC score	0.057813 (rank : 1496)
Query Neighborhood Hits	2923	Target Neighborhood Hits	987	Shared Neighborhood Hits	395
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

TVC_HUMAN
θ value	5.27518 (rank : 2526)	NC score	0.004383 (rank : 2665)
Query Neighborhood Hits	2923	Target Neighborhood Hits	179	Shared Neighborhood Hits	63
SwissProt Accessions	P03979	Gene names	TCRB
Domain Architecture
Description	T-cell receptor gamma chain V region PT-gamma-1/2 precursor.

UACA_MOUSE
θ value	5.27518 (rank : 2527)	NC score	0.050726 (rank : 1686)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1620	Shared Neighborhood Hits	492
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

UBR1_MOUSE
θ value	5.27518 (rank : 2528)	NC score	0.001544 (rank : 2778)
Query Neighborhood Hits	2923	Target Neighborhood Hits	52	Shared Neighborhood Hits	9
SwissProt Accessions	O70481, Q5BKR8, Q792M3, Q8BN40, Q8C5K3	Gene names	Ubr1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3 component N-recognin-1 (EC 6.-.-.-) (Ubiquitin-protein ligase E3-alpha-1) (Ubiquitin-protein ligase E3- alpha-I).

VPP4_HUMAN
θ value	5.27518 (rank : 2529)	NC score	0.001745 (rank : 2769)
Query Neighborhood Hits	2923	Target Neighborhood Hits	34	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HBG4	Gene names	ATP6V0A4, ATP6N1B
Domain Architecture
Description	Vacuolar proton translocating ATPase 116 kDa subunit a isoform 4 (V- ATPase 116 kDa isoform a4) (Vacuolar proton translocating ATPase 116 kDa subunit a kidney isoform).

WASF1_HUMAN
θ value	5.27518 (rank : 2530)	NC score	0.027334 (rank : 2057)
Query Neighborhood Hits	2923	Target Neighborhood Hits	260	Shared Neighborhood Hits	142
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

YETS2_HUMAN
θ value	5.27518 (rank : 2531)	NC score	0.021061 (rank : 2182)
Query Neighborhood Hits	2923	Target Neighborhood Hits	212	Shared Neighborhood Hits	92
SwissProt Accessions	Q9ULM3, Q641P6, Q9NW96	Gene names	YEATS2, KIAA1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

ZFP30_HUMAN
θ value	5.27518 (rank : 2532)	NC score	-0.029991 (rank : 3117)
Query Neighborhood Hits	2923	Target Neighborhood Hits	742	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y2G7, Q58EY8	Gene names	ZFP30, KIAA0961, ZNF745
Domain Architecture	No domain graphic available
Description	Zinc finger protein 30 homolog (Zfp-30) (Zinc finger protein 745).

ZN226_HUMAN
θ value	5.27518 (rank : 2533)	NC score	-0.029712 (rank : 3115)
Query Neighborhood Hits	2923	Target Neighborhood Hits	770	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NYT6, Q96TE6, Q9NS44	Gene names	ZNF226
Domain Architecture
Description	Zinc finger protein 226.

ZN282_HUMAN
θ value	5.27518 (rank : 2534)	NC score	-0.030144 (rank : 3122)
Query Neighborhood Hits	2923	Target Neighborhood Hits	796	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UDV7, O43691, Q6DKK0	Gene names	ZNF282, HUB1
Domain Architecture
Description	Zinc finger protein 282 (HTLV-I U5RE-binding protein 1) (HUB-1).

ZN292_HUMAN
θ value	5.27518 (rank : 2535)	NC score	-0.011775 (rank : 3062)
Query Neighborhood Hits	2923	Target Neighborhood Hits	918	Shared Neighborhood Hits	189
SwissProt Accessions	O60281, Q9H8G3, Q9H8J4	Gene names	ZNF292, KIAA0530
Domain Architecture	No domain graphic available
Description	Zinc finger protein 292.

ZN512_HUMAN
θ value	5.27518 (rank : 2536)	NC score	-0.011231 (rank : 3060)
Query Neighborhood Hits	2923	Target Neighborhood Hits	444	Shared Neighborhood Hits	39
SwissProt Accessions	Q96ME7, Q96JM0	Gene names	ZNF512, KIAA1805
Domain Architecture	No domain graphic available
Description	Zinc finger protein 512.

ZN571_HUMAN
θ value	5.27518 (rank : 2537)	NC score	-0.030082 (rank : 3120)
Query Neighborhood Hits	2923	Target Neighborhood Hits	755	Shared Neighborhood Hits	62
SwissProt Accessions	Q7Z3V5, Q3ZCU3, Q9NZX7	Gene names	ZNF571
Domain Architecture	No domain graphic available
Description	Zinc finger protein 571.

ZN639_HUMAN
θ value	5.27518 (rank : 2538)	NC score	-0.027453 (rank : 3096)
Query Neighborhood Hits	2923	Target Neighborhood Hits	723	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UID6	Gene names	ZNF639, ZASC1
Domain Architecture	No domain graphic available
Description	Zinc finger protein 639 (Zinc finger protein ZASC1) (Zinc finger protein ANC_2H01).

ZO1_HUMAN
θ value	5.27518 (rank : 2539)	NC score	0.022041 (rank : 2169)
Query Neighborhood Hits	2923	Target Neighborhood Hits	474	Shared Neighborhood Hits	181
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ZSCA2_HUMAN
θ value	5.27518 (rank : 2540)	NC score	-0.030150 (rank : 3123)
Query Neighborhood Hits	2923	Target Neighborhood Hits	803	Shared Neighborhood Hits	80
SwissProt Accessions	Q7Z7L9, Q6ZQY9, Q9NWU4	Gene names	ZSCAN2, ZFP29
Domain Architecture	No domain graphic available
Description	Zinc finger and SCAN domain-containing protein 2 (Zinc finger protein 29 homolog) (Zfp-29).

2ACA_HUMAN
θ value	6.88961 (rank : 2541)	NC score	0.008100 (rank : 2535)
Query Neighborhood Hits	2923	Target Neighborhood Hits	100	Shared Neighborhood Hits	60
SwissProt Accessions	Q06190, Q06189, Q9NPQ5	Gene names	PPP2R3A, PPP2R3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 72/130 kDa regulatory subunit B (PP2A, subunit B, B''-PR72/PR130) (PP2A, subunit B, B72/B130 isoforms) (PP2A, subunit B, PR72/PR130 isoforms) (PP2A, subunit B, R3 isoform).

4ET_MOUSE
θ value	6.88961 (rank : 2542)	NC score	0.005728 (rank : 2607)
Query Neighborhood Hits	2923	Target Neighborhood Hits	103	Shared Neighborhood Hits	42
SwissProt Accessions	Q9EST3, Q9CSS3	Gene names	Eif4enif1, Clast4
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4E transporter (eIF4E transporter) (4E-T) (Eukaryotic translation initiation factor 4E nuclear import factor 1).

AAMP_HUMAN
θ value	6.88961 (rank : 2543)	NC score	-0.015261 (rank : 3075)
Query Neighborhood Hits	2923	Target Neighborhood Hits	294	Shared Neighborhood Hits	18
SwissProt Accessions	Q13685, Q8WUJ9, Q96H92	Gene names	AAMP
Domain Architecture
Description	Angio-associated migratory cell protein.

ABCBB_HUMAN
θ value	6.88961 (rank : 2544)	NC score	-0.008753 (rank : 3043)
Query Neighborhood Hits	2923	Target Neighborhood Hits	103	Shared Neighborhood Hits	12
SwissProt Accessions	O95342, Q9UNB2	Gene names	ABCB11, BSEP
Domain Architecture
Description	Bile salt export pump (ATP-binding cassette sub-family B member 11).

AFF1_HUMAN
θ value	6.88961 (rank : 2545)	NC score	0.046158 (rank : 1749)
Query Neighborhood Hits	2923	Target Neighborhood Hits	506	Shared Neighborhood Hits	226
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

ALO17_HUMAN
θ value	6.88961 (rank : 2546)	NC score	0.026813 (rank : 2068)
Query Neighborhood Hits	2923	Target Neighborhood Hits	317	Shared Neighborhood Hits	118
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

APBA2_MOUSE
θ value	6.88961 (rank : 2547)	NC score	0.005843 (rank : 2605)
Query Neighborhood Hits	2923	Target Neighborhood Hits	219	Shared Neighborhood Hits	50
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

ARRD4_HUMAN
θ value	6.88961 (rank : 2548)	NC score	-0.000647 (rank : 2865)
Query Neighborhood Hits	2923	Target Neighborhood Hits	27	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NCT1, Q6NSI9	Gene names	ARRDC4
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 4.

ATX2_MOUSE
θ value	6.88961 (rank : 2549)	NC score	0.025257 (rank : 2103)
Query Neighborhood Hits	2923	Target Neighborhood Hits	445	Shared Neighborhood Hits	177
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

BAP1_HUMAN
θ value	6.88961 (rank : 2550)	NC score	0.007624 (rank : 2550)
Query Neighborhood Hits	2923	Target Neighborhood Hits	106	Shared Neighborhood Hits	44
SwissProt Accessions	Q92560, Q6LEM0, Q7Z5E8	Gene names	BAP1, KIAA0272
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1- associated protein 1) (Cerebral protein 6).

BPA1_MOUSE
θ value	6.88961 (rank : 2551)	NC score	0.040100 (rank : 1844)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1477	Shared Neighborhood Hits	473
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

BPIL3_MOUSE
θ value	6.88961 (rank : 2552)	NC score	-0.001214 (rank : 2889)
Query Neighborhood Hits	2923	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BU51, Q80ZU8	Gene names	Bpil3
Domain Architecture
Description	Bactericidal/permeability-increasing protein-like 3 precursor.

BRD7_MOUSE
θ value	6.88961 (rank : 2553)	NC score	0.003940 (rank : 2679)
Query Neighborhood Hits	2923	Target Neighborhood Hits	141	Shared Neighborhood Hits	63
SwissProt Accessions	O88665, Q3UQ56, Q3UU06, Q9CT78	Gene names	Brd7, Bp75
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein).

BTNL8_HUMAN
θ value	6.88961 (rank : 2554)	NC score	0.037951 (rank : 1877)
Query Neighborhood Hits	2923	Target Neighborhood Hits	177	Shared Neighborhood Hits	102
SwissProt Accessions	Q6UX41, Q9H730	Gene names	BTNL8
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 8 precursor.

CA065_HUMAN
θ value	6.88961 (rank : 2555)	NC score	0.063261 (rank : 1368)
Query Neighborhood Hits	2923	Target Neighborhood Hits	469	Shared Neighborhood Hits	266
SwissProt Accessions	Q8N715, Q8N746, Q8NA93	Gene names	C1orf65
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf65.

CAC1A_HUMAN
θ value	6.88961 (rank : 2556)	NC score	0.003839 (rank : 2686)
Query Neighborhood Hits	2923	Target Neighborhood Hits	387	Shared Neighborhood Hits	128
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1A_MOUSE
θ value	6.88961 (rank : 2557)	NC score	-0.001882 (rank : 2906)
Query Neighborhood Hits	2923	Target Neighborhood Hits	267	Shared Neighborhood Hits	82
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAD16_HUMAN
θ value	6.88961 (rank : 2558)	NC score	-0.009066 (rank : 3047)
Query Neighborhood Hits	2923	Target Neighborhood Hits	159	Shared Neighborhood Hits	40
SwissProt Accessions	O75309, Q6UW93	Gene names	CDH16
Domain Architecture
Description	Cadherin-16 precursor (Kidney-specific cadherin) (Ksp-cadherin).

CC017_HUMAN
θ value	6.88961 (rank : 2559)	NC score	0.005375 (rank : 2616)
Query Neighborhood Hits	2923	Target Neighborhood Hits	6	Shared Neighborhood Hits	6
SwissProt Accessions	Q6NW34, Q68DM6, Q9H7U0, Q9UFM4	Gene names	C3orf17
Domain Architecture	No domain graphic available
Description	Protein C3orf17.

CCS_HUMAN
θ value	6.88961 (rank : 2560)	NC score	0.000230 (rank : 2833)
Query Neighborhood Hits	2923	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	O14618	Gene names	CCS
Domain Architecture
Description	Copper chaperone for superoxide dismutase (Superoxide dismutase copper chaperone).

CDC37_HUMAN
θ value	6.88961 (rank : 2561)	NC score	0.043223 (rank : 1793)
Query Neighborhood Hits	2923	Target Neighborhood Hits	506	Shared Neighborhood Hits	254
SwissProt Accessions	Q16543	Gene names	CDC37
Domain Architecture
Description	Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37).

CELR2_MOUSE
θ value	6.88961 (rank : 2562)	NC score	0.000801 (rank : 2812)
Query Neighborhood Hits	2923	Target Neighborhood Hits	584	Shared Neighborhood Hits	109
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

CENPH_HUMAN
θ value	6.88961 (rank : 2563)	NC score	0.036673 (rank : 1895)
Query Neighborhood Hits	2923	Target Neighborhood Hits	335	Shared Neighborhood Hits	188
SwissProt Accessions	Q9H3R5	Gene names	CENPH, ICEN35
Domain Architecture	No domain graphic available
Description	Centromere protein H (CENP-H) (Interphase centromere complex protein 35).

CF010_HUMAN
θ value	6.88961 (rank : 2564)	NC score	0.047159 (rank : 1739)
Query Neighborhood Hits	2923	Target Neighborhood Hits	329	Shared Neighborhood Hits	152
SwissProt Accessions	Q5SRN2, Q5SPI9, Q5SPJ0, Q5SPK9, Q5SPL0, Q5SRN3, Q5TG25, Q5TG26, Q8N4B6	Gene names	C6orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf10.

CF057_MOUSE
θ value	6.88961 (rank : 2565)	NC score	0.004840 (rank : 2645)
Query Neighborhood Hits	2923	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BTE0, Q9CQN5, Q9D537	Gene names
Domain Architecture	No domain graphic available
Description	UPF0369 protein C6orf57 homolog precursor.

CHD2_HUMAN
θ value	6.88961 (rank : 2566)	NC score	0.007105 (rank : 2570)
Query Neighborhood Hits	2923	Target Neighborhood Hits	360	Shared Neighborhood Hits	144
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

CING_HUMAN
θ value	6.88961 (rank : 2567)	NC score	0.060943 (rank : 1415)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1275	Shared Neighborhood Hits	468
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

CN021_HUMAN
θ value	6.88961 (rank : 2568)	NC score	0.001698 (rank : 2770)
Query Neighborhood Hits	2923	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	Q86U38, Q8IVF0, Q8TBS6	Gene names	C14orf21, KIAA2021
Domain Architecture	No domain graphic available
Description	Protein C14orf21.

CN037_HUMAN
θ value	6.88961 (rank : 2569)	NC score	0.017061 (rank : 2261)
Query Neighborhood Hits	2923	Target Neighborhood Hits	118	Shared Neighborhood Hits	51
SwissProt Accessions	Q86TY3, Q6P5Q1, Q86TY1	Gene names	C14orf37
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 precursor.

CN037_MOUSE
θ value	6.88961 (rank : 2570)	NC score	0.014217 (rank : 2348)
Query Neighborhood Hits	2923	Target Neighborhood Hits	179	Shared Neighborhood Hits	72
SwissProt Accessions	Q8BT18, Q8BFQ7, Q8R1Q5, Q9D6C5	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 homolog precursor.

CNGB1_HUMAN
θ value	6.88961 (rank : 2571)	NC score	0.014830 (rank : 2327)
Query Neighborhood Hits	2923	Target Neighborhood Hits	222	Shared Neighborhood Hits	98
SwissProt Accessions	Q14028, Q14029	Gene names	CNGB1, CNCG4
Domain Architecture
Description	Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).

CO1A1_MOUSE
θ value	6.88961 (rank : 2572)	NC score	0.015605 (rank : 2300)
Query Neighborhood Hits	2923	Target Neighborhood Hits	457	Shared Neighborhood Hits	142
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

COG3_HUMAN
θ value	6.88961 (rank : 2573)	NC score	0.006515 (rank : 2589)
Query Neighborhood Hits	2923	Target Neighborhood Hits	56	Shared Neighborhood Hits	24
SwissProt Accessions	Q96JB2, Q5VT70, Q8IXX4, Q9BZ92	Gene names	COG3, SEC34
Domain Architecture
Description	Conserved oligomeric Golgi complex component 3 (Vesicle docking protein SEC34 homolog) (p94).

COGA1_HUMAN
θ value	6.88961 (rank : 2574)	NC score	0.020173 (rank : 2200)
Query Neighborhood Hits	2923	Target Neighborhood Hits	345	Shared Neighborhood Hits	105
SwissProt Accessions	Q07092	Gene names	COL16A1
Domain Architecture
Description	Collagen alpha-1(XVI) chain precursor.

CS007_HUMAN
θ value	6.88961 (rank : 2575)	NC score	0.023987 (rank : 2128)
Query Neighborhood Hits	2923	Target Neighborhood Hits	401	Shared Neighborhood Hits	170
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

CSPG2_HUMAN
θ value	6.88961 (rank : 2576)	NC score	0.015801 (rank : 2292)
Query Neighborhood Hits	2923	Target Neighborhood Hits	681	Shared Neighborhood Hits	175
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

CT102_MOUSE
θ value	6.88961 (rank : 2577)	NC score	0.024610 (rank : 2116)
Query Neighborhood Hits	2923	Target Neighborhood Hits	46	Shared Neighborhood Hits	30
SwissProt Accessions	Q6PDS0	Gene names	Gm691
Domain Architecture	No domain graphic available
Description	Protein C20orf102 homolog precursor.

CT195_MOUSE
θ value	6.88961 (rank : 2578)	NC score	0.011005 (rank : 2443)
Query Neighborhood Hits	2923	Target Neighborhood Hits	15	Shared Neighborhood Hits	9
SwissProt Accessions	Q80WB0	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf195 homolog.

DDEF1_MOUSE
θ value	6.88961 (rank : 2579)	NC score	0.009506 (rank : 2488)
Query Neighborhood Hits	2923	Target Neighborhood Hits	592	Shared Neighborhood Hits	169
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

DDX24_MOUSE
θ value	6.88961 (rank : 2580)	NC score	-0.007085 (rank : 3009)
Query Neighborhood Hits	2923	Target Neighborhood Hits	147	Shared Neighborhood Hits	38
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX49_HUMAN
θ value	6.88961 (rank : 2581)	NC score	-0.007304 (rank : 3013)
Query Neighborhood Hits	2923	Target Neighborhood Hits	223	Shared Neighborhood Hits	82
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DHRS1_HUMAN
θ value	6.88961 (rank : 2582)	NC score	-0.005008 (rank : 2977)
Query Neighborhood Hits	2923	Target Neighborhood Hits	61	Shared Neighborhood Hits	4
SwissProt Accessions	Q96LJ7, Q8NDG3, Q96B59, Q96CQ5	Gene names	DHRS1
Domain Architecture
Description	Dehydrogenase/reductase SDR family member 1 (EC 1.1.-.-).

DHRS9_HUMAN
θ value	6.88961 (rank : 2583)	NC score	-0.006592 (rank : 3003)
Query Neighborhood Hits	2923	Target Neighborhood Hits	65	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BPW9, Q5RKX1, Q9NRA9, Q9NRB0	Gene names	DHRS9
Domain Architecture	No domain graphic available
Description	Dehydrogenase/reductase SDR family member 9 precursor (EC 1.1.-.-) (3- alpha hydroxysteroid dehydrogenase) (3alpha-HSD) (RDH-E2) (Short-chain dehydrogenase/reductase retSDR8) (NADP-dependent retinol dehydrogenase/reductase) (RDHL).

DLG1_HUMAN
θ value	6.88961 (rank : 2584)	NC score	0.004671 (rank : 2653)
Query Neighborhood Hits	2923	Target Neighborhood Hits	290	Shared Neighborhood Hits	70
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

DNPEP_HUMAN
θ value	6.88961 (rank : 2585)	NC score	0.003276 (rank : 2716)
Query Neighborhood Hits	2923	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ULA0, Q9BW44, Q9NUV5	Gene names	DNPEP
Domain Architecture
Description	Aspartyl aminopeptidase (EC 3.4.11.21).

DNPEP_MOUSE
θ value	6.88961 (rank : 2586)	NC score	0.003206 (rank : 2722)
Query Neighborhood Hits	2923	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z2W0	Gene names	Dnpep
Domain Architecture
Description	Aspartyl aminopeptidase (EC 3.4.11.21).

DOCK3_MOUSE
θ value	6.88961 (rank : 2587)	NC score	0.001963 (rank : 2765)
Query Neighborhood Hits	2923	Target Neighborhood Hits	93	Shared Neighborhood Hits	33
SwissProt Accessions	Q8CIQ7	Gene names	Dock3, Moca
Domain Architecture
Description	Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP protein).

DOK2_MOUSE
θ value	6.88961 (rank : 2588)	NC score	0.005465 (rank : 2612)
Query Neighborhood Hits	2923	Target Neighborhood Hits	244	Shared Neighborhood Hits	80
SwissProt Accessions	O70469, O70272, Q99KL1	Gene names	Dok2, Frip
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)) (Dok- related protein) (Dok-R) (IL-four receptor-interacting protein) (FRIP).

DPPA2_HUMAN
θ value	6.88961 (rank : 2589)	NC score	0.002773 (rank : 2733)
Query Neighborhood Hits	2923	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z7J5, Q8WVF0	Gene names	DPPA2, PESCRG1
Domain Architecture	No domain graphic available
Description	Developmental pluripotency-associated protein 2 (Pluripotent embryonic stem cell-related protein 1).

DYN2_MOUSE
θ value	6.88961 (rank : 2590)	NC score	0.004332 (rank : 2668)
Query Neighborhood Hits	2923	Target Neighborhood Hits	104	Shared Neighborhood Hits	40
SwissProt Accessions	P39054, Q9DBE1	Gene names	Dnm2, Dyn2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5) (Dynamin UDNM).

DZIP1_HUMAN
θ value	6.88961 (rank : 2591)	NC score	0.031648 (rank : 1990)
Query Neighborhood Hits	2923	Target Neighborhood Hits	675	Shared Neighborhood Hits	219
SwissProt Accessions	Q86YF9, Q8WY45, Q8WY46, Q9UGA5, Q9Y2K0	Gene names	DZIP1, DZIP, DZIP2, KIAA0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1/2).

EP300_HUMAN
θ value	6.88961 (rank : 2592)	NC score	0.049365 (rank : 1715)
Query Neighborhood Hits	2923	Target Neighborhood Hits	821	Shared Neighborhood Hits	332
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

EP400_MOUSE
θ value	6.88961 (rank : 2593)	NC score	0.024873 (rank : 2110)
Query Neighborhood Hits	2923	Target Neighborhood Hits	592	Shared Neighborhood Hits	252
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

EPC2_HUMAN
θ value	6.88961 (rank : 2594)	NC score	0.008038 (rank : 2536)
Query Neighborhood Hits	2923	Target Neighborhood Hits	58	Shared Neighborhood Hits	34
SwissProt Accessions	Q52LR7, Q7L9J1, Q96RR7, Q9NUT8, Q9NVR1, Q9UFM9	Gene names	EPC2
Domain Architecture	No domain graphic available
Description	Enhancer of polycomb homolog 2.

EPC2_MOUSE
θ value	6.88961 (rank : 2595)	NC score	0.009096 (rank : 2507)
Query Neighborhood Hits	2923	Target Neighborhood Hits	59	Shared Neighborhood Hits	38
SwissProt Accessions	Q8C0I4, Q3URX9, Q80Y70, Q8BXC5	Gene names	Epc2
Domain Architecture	No domain graphic available
Description	Enhancer of polycomb homolog 2.

F10A1_HUMAN
θ value	6.88961 (rank : 2596)	NC score	0.003666 (rank : 2698)
Query Neighborhood Hits	2923	Target Neighborhood Hits	312	Shared Neighborhood Hits	102
SwissProt Accessions	P50502, O14999	Gene names	ST13, FAM10A1, HIP, SNC6
Domain Architecture
Description	Hsc70-interacting protein (Hip) (Suppression of tumorigenicity protein 13) (Putative tumor suppressor ST13) (Protein FAM10A1) (Progesterone receptor-associated p48 protein) (NY-REN-33 antigen).

FA48A_HUMAN
θ value	6.88961 (rank : 2597)	NC score	0.008101 (rank : 2534)
Query Neighborhood Hits	2923	Target Neighborhood Hits	51	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NEM7, Q71RF3, Q9Y6A6	Gene names	FAM48A
Domain Architecture	No domain graphic available
Description	Protein FAM48A (p38-interacting protein) (p38IP).

FA53B_MOUSE
θ value	6.88961 (rank : 2598)	NC score	0.003044 (rank : 2725)
Query Neighborhood Hits	2923	Target Neighborhood Hits	29	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BGR5, Q3UGW1, Q8BI13	Gene names	Fam53b
Domain Architecture	No domain graphic available
Description	Protein FAM53B.

FAT2_HUMAN
θ value	6.88961 (rank : 2599)	NC score	-0.001160 (rank : 2886)
Query Neighborhood Hits	2923	Target Neighborhood Hits	507	Shared Neighborhood Hits	116
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

FBX24_HUMAN
θ value	6.88961 (rank : 2600)	NC score	0.004568 (rank : 2658)
Query Neighborhood Hits	2923	Target Neighborhood Hits	57	Shared Neighborhood Hits	8
SwissProt Accessions	O75426, Q9H0G1	Gene names	FBXO24, FBX24
Domain Architecture
Description	F-box only protein 24.

FBX24_MOUSE
θ value	6.88961 (rank : 2601)	NC score	0.004663 (rank : 2654)
Query Neighborhood Hits	2923	Target Neighborhood Hits	59	Shared Neighborhood Hits	10
SwissProt Accessions	Q9D417	Gene names	Fbxo24, Fbx24
Domain Architecture	No domain graphic available
Description	F-box only protein 24.

FOXO1_MOUSE
θ value	6.88961 (rank : 2602)	NC score	-0.007792 (rank : 3029)
Query Neighborhood Hits	2923	Target Neighborhood Hits	118	Shared Neighborhood Hits	19
SwissProt Accessions	Q9R1E0	Gene names	Foxo1a, Fkhr, Foxo1
Domain Architecture
Description	Forkhead box protein O1A (Forkhead in rhabdomyosarcoma).

FYCO1_MOUSE
θ value	6.88961 (rank : 2603)	NC score	0.046673 (rank : 1742)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1059	Shared Neighborhood Hits	372
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

FYV1_HUMAN
θ value	6.88961 (rank : 2604)	NC score	0.000441 (rank : 2824)
Query Neighborhood Hits	2923	Target Neighborhood Hits	217	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

G3BP_HUMAN
θ value	6.88961 (rank : 2605)	NC score	0.005131 (rank : 2628)
Query Neighborhood Hits	2923	Target Neighborhood Hits	219	Shared Neighborhood Hits	57
SwissProt Accessions	Q13283	Gene names	G3BP, G3BP1
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 1 (EC 3.6.1.-) (ATP- dependent DNA helicase VIII) (GAP SH3-domain-binding protein 1) (G3BP- 1) (HDH-VIII).

GBP2_MOUSE
θ value	6.88961 (rank : 2606)	NC score	0.026333 (rank : 2080)
Query Neighborhood Hits	2923	Target Neighborhood Hits	323	Shared Neighborhood Hits	182
SwissProt Accessions	Q9Z0E6, Q8CIC6, Q921N2, Q9R1I0	Gene names	Gbp2
Domain Architecture
Description	Interferon-induced guanylate-binding protein 2 (GTP-binding protein 2) (Guanine nucleotide-binding protein 2) (GBP-2) (mGBP2) (mGBP-2).

GBP4_HUMAN
θ value	6.88961 (rank : 2607)	NC score	0.029051 (rank : 2024)
Query Neighborhood Hits	2923	Target Neighborhood Hits	484	Shared Neighborhood Hits	226
SwissProt Accessions	Q96PP9, Q86T99	Gene names	GBP4
Domain Architecture
Description	Guanylate-binding protein 4 (GTP-binding protein 4) (Guanine nucleotide-binding protein 4) (GBP-4).

GFAP_MOUSE
θ value	6.88961 (rank : 2608)	NC score	0.025171 (rank : 2104)
Query Neighborhood Hits	2923	Target Neighborhood Hits	725	Shared Neighborhood Hits	306
SwissProt Accessions	P03995, Q7TQ30, Q925K3	Gene names	Gfap
Domain Architecture
Description	Glial fibrillary acidic protein, astrocyte (GFAP).

GLUD1_MOUSE
θ value	6.88961 (rank : 2609)	NC score	0.002070 (rank : 2761)
Query Neighborhood Hits	2923	Target Neighborhood Hits	23	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CIX8	Gene names	Gluld1, Lgs
Domain Architecture	No domain graphic available
Description	Glutamate--ammonia ligase domain-containing protein 1 (Lengsin) (Lens glutamine synthase-like).

GOGA2_MOUSE
θ value	6.88961 (rank : 2610)	NC score	0.056076 (rank : 1554)
Query Neighborhood Hits	2923	Target Neighborhood Hits	944	Shared Neighborhood Hits	342
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

GP124_HUMAN
θ value	6.88961 (rank : 2611)	NC score	0.037738 (rank : 1879)
Query Neighborhood Hits	2923	Target Neighborhood Hits	304	Shared Neighborhood Hits	72
SwissProt Accessions	Q96PE1, Q8N3R1, Q8TEM3, Q96KB2, Q9P1Z7, Q9UFY4	Gene names	GPR124, KIAA1531, TEM5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

GP149_HUMAN
θ value	6.88961 (rank : 2612)	NC score	0.000148 (rank : 2835)
Query Neighborhood Hits	2923	Target Neighborhood Hits	68	Shared Neighborhood Hits	8
SwissProt Accessions	Q86SP6	Gene names	GPR149, PGR10
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 149 (G-protein coupled receptor PGR10).

GP1BA_HUMAN
θ value	6.88961 (rank : 2613)	NC score	0.038001 (rank : 1876)
Query Neighborhood Hits	2923	Target Neighborhood Hits	407	Shared Neighborhood Hits	134
SwissProt Accessions	P07359, Q14441, Q16469, Q8N1F3, Q8NG39, Q9HDC7, Q9UEK1, Q9UQS4	Gene names	GP1BA
Domain Architecture
Description	Platelet glycoprotein Ib alpha chain precursor (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (Antigen CD42b-alpha) (CD42b antigen) [Contains: Glycocalicin].

GPDM_MOUSE
θ value	6.88961 (rank : 2614)	NC score	-0.001344 (rank : 2894)
Query Neighborhood Hits	2923	Target Neighborhood Hits	101	Shared Neighborhood Hits	8
SwissProt Accessions	Q64521, Q61507	Gene names	Gpd2, Gdm1
Domain Architecture
Description	Glycerol-3-phosphate dehydrogenase, mitochondrial precursor (EC 1.1.99.5) (GPD-M) (GPDH-M).

GPVI_MOUSE
θ value	6.88961 (rank : 2615)	NC score	0.035841 (rank : 1909)
Query Neighborhood Hits	2923	Target Neighborhood Hits	90	Shared Neighborhood Hits	66
SwissProt Accessions	P0C191	Gene names	Gp6
Domain Architecture	No domain graphic available
Description	Platelet glycoprotein VI precursor (GPVI).

GRSF1_MOUSE
θ value	6.88961 (rank : 2616)	NC score	-0.002504 (rank : 2919)
Query Neighborhood Hits	2923	Target Neighborhood Hits	60	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C5Q4, Q8BR05, Q8BRG7	Gene names	Grsf1
Domain Architecture	No domain graphic available
Description	G-rich sequence factor 1 (GRSF-1).

HA2S_MOUSE
θ value	6.88961 (rank : 2617)	NC score	-0.001266 (rank : 2891)
Query Neighborhood Hits	2923	Target Neighborhood Hits	200	Shared Neighborhood Hits	46
SwissProt Accessions	P14437	Gene names
Domain Architecture
Description	H-2 class II histocompatibility antigen, A-S alpha chain.

HASP_HUMAN
θ value	6.88961 (rank : 2618)	NC score	0.033776 (rank : 1954)
Query Neighborhood Hits	2923	Target Neighborhood Hits	64	Shared Neighborhood Hits	40
SwissProt Accessions	Q8TF76, Q5U5K3, Q96MN1, Q9BXS7	Gene names	GSG2
Domain Architecture
Description	Serine/threonine-protein kinase Haspin (EC 2.7.11.1) (Haploid germ cell-specific nuclear protein kinase) (H-Haspin) (Germ cell-specific gene 2 protein).

HD_HUMAN
θ value	6.88961 (rank : 2619)	NC score	0.009656 (rank : 2483)
Query Neighborhood Hits	2923	Target Neighborhood Hits	165	Shared Neighborhood Hits	71
SwissProt Accessions	P42858, Q9UQB7	Gene names	HD, IT15
Domain Architecture
Description	Huntingtin (Huntington disease protein) (HD protein).

HPS5_MOUSE
θ value	6.88961 (rank : 2620)	NC score	0.003865 (rank : 2685)
Query Neighborhood Hits	2923	Target Neighborhood Hits	69	Shared Neighborhood Hits	28
SwissProt Accessions	P59438	Gene names	Hps5, Ru2
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 5 protein homolog (Ruby-eye protein 2) (Ru2).

HS12A_HUMAN
θ value	6.88961 (rank : 2621)	NC score	0.001075 (rank : 2798)
Query Neighborhood Hits	2923	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	O43301	Gene names	HSPA12A, KIAA0417
Domain Architecture
Description	Heat shock 70 kDa protein 12A.

HS12A_MOUSE
θ value	6.88961 (rank : 2622)	NC score	0.002229 (rank : 2755)
Query Neighborhood Hits	2923	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K0U4, Q3UQZ8	Gene names	Hspa12a
Domain Architecture
Description	Heat shock 70 kDa protein 12A.

IFT74_HUMAN
θ value	6.88961 (rank : 2623)	NC score	0.053971 (rank : 1616)
Query Neighborhood Hits	2923	Target Neighborhood Hits	949	Shared Neighborhood Hits	370
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

IGHD_HUMAN
θ value	6.88961 (rank : 2624)	NC score	0.023395 (rank : 2138)
Query Neighborhood Hits	2923	Target Neighborhood Hits	194	Shared Neighborhood Hits	59
SwissProt Accessions	P01880	Gene names	IGHD
Domain Architecture	No domain graphic available
Description	Ig delta chain C region.

KAISO_MOUSE
θ value	6.88961 (rank : 2625)	NC score	-0.029223 (rank : 3109)
Query Neighborhood Hits	2923	Target Neighborhood Hits	821	Shared Neighborhood Hits	84
SwissProt Accessions	Q8BN78, Q8C226, Q9WTZ7	Gene names	Zbtb33, Kaiso
Domain Architecture	No domain graphic available
Description	Transcriptional regulator Kaiso (Zinc finger and BTB domain-containing protein 33).

KBTB2_HUMAN
θ value	6.88961 (rank : 2626)	NC score	-0.012968 (rank : 3067)
Query Neighborhood Hits	2923	Target Neighborhood Hits	179	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IY47, Q86Y62, Q9P239, Q9UFM7	Gene names	KBTBD2, BKLHD1, KIAA1489
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 2 (BTB and kelch domain-containing protein 1).

KCNA2_HUMAN
θ value	6.88961 (rank : 2627)	NC score	-0.008302 (rank : 3034)
Query Neighborhood Hits	2923	Target Neighborhood Hits	101	Shared Neighborhood Hits	7
SwissProt Accessions	P16389	Gene names	KCNA2
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (HBK5) (NGK1) (HUKIV).

KCNA2_MOUSE
θ value	6.88961 (rank : 2628)	NC score	-0.008300 (rank : 3033)
Query Neighborhood Hits	2923	Target Neighborhood Hits	102	Shared Neighborhood Hits	7
SwissProt Accessions	P63141, P15386, Q02010, Q8C8W4	Gene names	Kcna2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (MK2).

KIF1C_MOUSE
θ value	6.88961 (rank : 2629)	NC score	0.003935 (rank : 2680)
Query Neighborhood Hits	2923	Target Neighborhood Hits	171	Shared Neighborhood Hits	84
SwissProt Accessions	O35071, Q5SX62	Gene names	Kif1c
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF1C.

KINH_HUMAN
θ value	6.88961 (rank : 2630)	NC score	0.043676 (rank : 1783)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1231	Shared Neighborhood Hits	456
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

KLH13_HUMAN
θ value	6.88961 (rank : 2631)	NC score	-0.011858 (rank : 3064)
Query Neighborhood Hits	2923	Target Neighborhood Hits	193	Shared Neighborhood Hits	19
SwissProt Accessions	Q9P2N7, Q6P2E3, Q96QI7, Q9UDN9	Gene names	KLHL13, BKLHD2, KIAA1309
Domain Architecture
Description	Kelch-like protein 13 (BTB and kelch domain-containing protein 2).

KLK1_HUMAN
θ value	6.88961 (rank : 2632)	NC score	-0.017037 (rank : 3078)
Query Neighborhood Hits	2923	Target Neighborhood Hits	183	Shared Neighborhood Hits	8
SwissProt Accessions	P06870, Q8TCV8, Q9BS53, Q9NQU4, Q9UMJ1	Gene names	KLK1
Domain Architecture
Description	Kallikrein-1 precursor (EC 3.4.21.35) (Tissue kallikrein) (Kidney/pancreas/salivary gland kallikrein).

KV1K_HUMAN
θ value	6.88961 (rank : 2633)	NC score	-0.003964 (rank : 2957)
Query Neighborhood Hits	2923	Target Neighborhood Hits	220	Shared Neighborhood Hits	65
SwissProt Accessions	P01603	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-I region Ka.

KV3M_MOUSE
θ value	6.88961 (rank : 2634)	NC score	-0.003345 (rank : 2942)
Query Neighborhood Hits	2923	Target Neighborhood Hits	238	Shared Neighborhood Hits	74
SwissProt Accessions	P01665	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-III region PC 7043.

KV3N_MOUSE
θ value	6.88961 (rank : 2635)	NC score	-0.003448 (rank : 2945)
Query Neighborhood Hits	2923	Target Neighborhood Hits	236	Shared Neighborhood Hits	75
SwissProt Accessions	P01666	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-III region PC 7183.

KV3O_MOUSE
θ value	6.88961 (rank : 2636)	NC score	-0.003502 (rank : 2948)
Query Neighborhood Hits	2923	Target Neighborhood Hits	242	Shared Neighborhood Hits	76
SwissProt Accessions	P01667	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-III region PC 6308.

KV3Q_MOUSE
θ value	6.88961 (rank : 2637)	NC score	-0.003813 (rank : 2955)
Query Neighborhood Hits	2923	Target Neighborhood Hits	225	Shared Neighborhood Hits	70
SwissProt Accessions	P01669	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-III region PC 7769.

KV5T_MOUSE
θ value	6.88961 (rank : 2638)	NC score	-0.004864 (rank : 2973)
Query Neighborhood Hits	2923	Target Neighborhood Hits	243	Shared Neighborhood Hits	67
SwissProt Accessions	P01653	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-V region W3082.

KV6F_MOUSE
θ value	6.88961 (rank : 2639)	NC score	-0.003455 (rank : 2946)
Query Neighborhood Hits	2923	Target Neighborhood Hits	277	Shared Neighborhood Hits	77
SwissProt Accessions	P04940	Gene names
Domain Architecture
Description	Ig kappa chain V-VI region NQ2-17.4.1.

KV6G_MOUSE
θ value	6.88961 (rank : 2640)	NC score	-0.003550 (rank : 2950)
Query Neighborhood Hits	2923	Target Neighborhood Hits	278	Shared Neighborhood Hits	77
SwissProt Accessions	P04941	Gene names
Domain Architecture
Description	Ig kappa chain V-VI region NQ2-48.2.2.

KV6I_MOUSE
θ value	6.88961 (rank : 2641)	NC score	-0.002918 (rank : 2932)
Query Neighborhood Hits	2923	Target Neighborhood Hits	272	Shared Neighborhood Hits	77
SwissProt Accessions	P04943	Gene names
Domain Architecture
Description	Ig kappa chain V-VI region NQ6-8.3.1.

LAMA5_MOUSE
θ value	6.88961 (rank : 2642)	NC score	0.042156 (rank : 1809)
Query Neighborhood Hits	2923	Target Neighborhood Hits	828	Shared Neighborhood Hits	253
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LTB1L_HUMAN
θ value	6.88961 (rank : 2643)	NC score	0.017575 (rank : 2250)
Query Neighborhood Hits	2923	Target Neighborhood Hits	553	Shared Neighborhood Hits	124
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	6.88961 (rank : 2644)	NC score	0.017212 (rank : 2258)
Query Neighborhood Hits	2923	Target Neighborhood Hits	502	Shared Neighborhood Hits	106
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LV2B_HUMAN
θ value	6.88961 (rank : 2645)	NC score	-0.006710 (rank : 3005)
Query Neighborhood Hits	2923	Target Neighborhood Hits	234	Shared Neighborhood Hits	62
SwissProt Accessions	P01705	Gene names
Domain Architecture	No domain graphic available
Description	Ig lambda chain V-II region NEI.

LV2G_HUMAN
θ value	6.88961 (rank : 2646)	NC score	-0.006498 (rank : 3001)
Query Neighborhood Hits	2923	Target Neighborhood Hits	263	Shared Neighborhood Hits	62
SwissProt Accessions	P01710	Gene names
Domain Architecture	No domain graphic available
Description	Ig lambda chain V-II region BO.

MAGD4_HUMAN
θ value	6.88961 (rank : 2647)	NC score	0.005464 (rank : 2613)
Query Neighborhood Hits	2923	Target Neighborhood Hits	338	Shared Neighborhood Hits	124
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

MBIP1_MOUSE
θ value	6.88961 (rank : 2648)	NC score	0.004971 (rank : 2637)
Query Neighborhood Hits	2923	Target Neighborhood Hits	20	Shared Neighborhood Hits	10
SwissProt Accessions	Q99LQ1, Q3TBM3	Gene names	Mbip
Domain Architecture	No domain graphic available
Description	MAP3K12-binding inhibitory protein 1 (MAPK upstream kinase-binding inhibitory protein) (MUK-binding inhibitory protein).

MGP_HUMAN
θ value	6.88961 (rank : 2649)	NC score	0.006151 (rank : 2598)
Query Neighborhood Hits	2923	Target Neighborhood Hits	3	Shared Neighborhood Hits	3
SwissProt Accessions	P08493	Gene names	MGP, MGLAP
Domain Architecture
Description	Matrix Gla-protein precursor (MGP).

MILK1_HUMAN
θ value	6.88961 (rank : 2650)	NC score	0.031654 (rank : 1989)
Query Neighborhood Hits	2923	Target Neighborhood Hits	427	Shared Neighborhood Hits	198
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MLL3_HUMAN
θ value	6.88961 (rank : 2651)	NC score	0.035054 (rank : 1929)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1644	Shared Neighborhood Hits	509
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MLL4_HUMAN
θ value	6.88961 (rank : 2652)	NC score	0.043356 (rank : 1788)
Query Neighborhood Hits	2923	Target Neighborhood Hits	722	Shared Neighborhood Hits	298
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

MY18A_HUMAN
θ value	6.88961 (rank : 2653)	NC score	0.062448 (rank : 1387)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1929	Shared Neighborhood Hits	603
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MYPT2_HUMAN
θ value	6.88961 (rank : 2654)	NC score	0.012527 (rank : 2400)
Query Neighborhood Hits	2923	Target Neighborhood Hits	707	Shared Neighborhood Hits	253
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

MYST4_HUMAN
θ value	6.88961 (rank : 2655)	NC score	0.022275 (rank : 2163)
Query Neighborhood Hits	2923	Target Neighborhood Hits	671	Shared Neighborhood Hits	285
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

NADAP_HUMAN
θ value	6.88961 (rank : 2656)	NC score	0.012842 (rank : 2389)
Query Neighborhood Hits	2923	Target Neighborhood Hits	208	Shared Neighborhood Hits	99
SwissProt Accessions	Q9BWU0, Q4KMT1, Q4KMX0, Q7Z5Q9, Q9NVN2	Gene names	SLC4A1AP, HLC3
Domain Architecture	No domain graphic available
Description	Kanadaptin (Kidney anion exchanger adapter protein) (Solute carrier family 4 anion exchanger member 1 adapter protein) (Lung cancer oncogene 3 protein).

NEBU_HUMAN
θ value	6.88961 (rank : 2657)	NC score	0.014889 (rank : 2326)
Query Neighborhood Hits	2923	Target Neighborhood Hits	420	Shared Neighborhood Hits	149
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

NIBL_MOUSE
θ value	6.88961 (rank : 2658)	NC score	0.005154 (rank : 2624)
Query Neighborhood Hits	2923	Target Neighborhood Hits	54	Shared Neighborhood Hits	26
SwissProt Accessions	Q8R1F1	Gene names
Domain Architecture	No domain graphic available
Description	Niban-like protein.

NMDE1_MOUSE
θ value	6.88961 (rank : 2659)	NC score	-0.006024 (rank : 2995)
Query Neighborhood Hits	2923	Target Neighborhood Hits	84	Shared Neighborhood Hits	17
SwissProt Accessions	P35436	Gene names	Grin2a
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit epsilon 1 precursor (N-methyl D- aspartate receptor subtype 2A) (NR2A) (NMDAR2A).

NOL4_MOUSE
θ value	6.88961 (rank : 2660)	NC score	0.001287 (rank : 2789)
Query Neighborhood Hits	2923	Target Neighborhood Hits	44	Shared Neighborhood Hits	13
SwissProt Accessions	P60954	Gene names	Nol4
Domain Architecture	No domain graphic available
Description	Nucleolar protein 4.

NPAS2_HUMAN
θ value	6.88961 (rank : 2661)	NC score	-0.000892 (rank : 2875)
Query Neighborhood Hits	2923	Target Neighborhood Hits	150	Shared Neighborhood Hits	52
SwissProt Accessions	Q99743, Q99629	Gene names	NPAS2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2) (Member of PAS protein 4) (MOP4).

NUP88_HUMAN
θ value	6.88961 (rank : 2662)	NC score	0.033215 (rank : 1963)
Query Neighborhood Hits	2923	Target Neighborhood Hits	354	Shared Neighborhood Hits	198
SwissProt Accessions	Q99567, Q9BWE5	Gene names	NUP88
Domain Architecture	No domain graphic available
Description	Nuclear pore complex protein Nup88 (Nucleoporin Nup88) (88 kDa nuclear pore complex protein).

NUP98_HUMAN
θ value	6.88961 (rank : 2663)	NC score	0.006688 (rank : 2581)
Query Neighborhood Hits	2923	Target Neighborhood Hits	81	Shared Neighborhood Hits	29
SwissProt Accessions	P52948, Q8IUT2, Q8WYB0, Q96E54, Q9H3Q4, Q9NT02, Q9UF57, Q9UHX0, Q9Y6J4, Q9Y6J5	Gene names	NUP98
Domain Architecture
Description	Nuclear pore complex protein Nup98-Nup96 precursor [Contains: Nuclear pore complex protein Nup98 (Nucleoporin Nup98) (98 kDa nucleoporin); Nuclear pore complex protein Nup96 (Nucleoporin Nup96) (96 kDa nucleoporin)].

OXRP_HUMAN
θ value	6.88961 (rank : 2664)	NC score	0.016942 (rank : 2265)
Query Neighborhood Hits	2923	Target Neighborhood Hits	544	Shared Neighborhood Hits	216
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

P85B_HUMAN
θ value	6.88961 (rank : 2665)	NC score	0.057156 (rank : 1522)
Query Neighborhood Hits	2923	Target Neighborhood Hits	543	Shared Neighborhood Hits	262
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

PACS1_MOUSE
θ value	6.88961 (rank : 2666)	NC score	0.011334 (rank : 2432)
Query Neighborhood Hits	2923	Target Neighborhood Hits	87	Shared Neighborhood Hits	43
SwissProt Accessions	Q8K212, Q6P5H8	Gene names	Pacs1
Domain Architecture	No domain graphic available
Description	Phosphofurin acidic cluster sorting protein 1 (PACS-1).

PALM_MOUSE
θ value	6.88961 (rank : 2667)	NC score	0.022628 (rank : 2155)
Query Neighborhood Hits	2923	Target Neighborhood Hits	228	Shared Neighborhood Hits	123
SwissProt Accessions	Q9Z0P4, Q9Z0P3	Gene names	Palm
Domain Architecture
Description	Paralemmin.

PCDB3_HUMAN
θ value	6.88961 (rank : 2668)	NC score	-0.008735 (rank : 3042)
Query Neighborhood Hits	2923	Target Neighborhood Hits	159	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y5E6	Gene names	PCDHB3
Domain Architecture
Description	Protocadherin beta 3 precursor (PCDH-beta3).

PCDG1_HUMAN
θ value	6.88961 (rank : 2669)	NC score	-0.008948 (rank : 3045)
Query Neighborhood Hits	2923	Target Neighborhood Hits	158	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y5H4, Q9Y5D6	Gene names	PCDHGA1
Domain Architecture
Description	Protocadherin gamma A1 precursor (PCDH-gamma-A1).

PDCD2_HUMAN
θ value	6.88961 (rank : 2670)	NC score	0.002893 (rank : 2730)
Query Neighborhood Hits	2923	Target Neighborhood Hits	29	Shared Neighborhood Hits	6
SwissProt Accessions	Q16342, Q9UH12	Gene names	PDCD2, RP8, ZMYND7
Domain Architecture
Description	Programmed cell death protein 2 (Zinc finger protein Rp-8) (Zinc finger MYND domain-containing protein 7).

PHYIP_HUMAN
θ value	6.88961 (rank : 2671)	NC score	0.004597 (rank : 2656)
Query Neighborhood Hits	2923	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	Q92561, Q8N4I9	Gene names	PHYHIP, KIAA0273
Domain Architecture
Description	Phytanoyl-CoA hydroxylase-interacting protein (Phytanoyl-CoA hydroxylase-associated protein 1) (PAHXAP1) (PAHX-AP1).

PHYIP_MOUSE
θ value	6.88961 (rank : 2672)	NC score	0.004597 (rank : 2655)
Query Neighborhood Hits	2923	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K0S0	Gene names	Phyhip
Domain Architecture
Description	Phytanoyl-CoA hydroxylase-interacting protein (Phytanoyl-CoA hydroxylase-associated protein 1) (PAHXAP1) (PAHX-AP1).

PO2F1_HUMAN
θ value	6.88961 (rank : 2673)	NC score	-0.008506 (rank : 3040)
Query Neighborhood Hits	2923	Target Neighborhood Hits	426	Shared Neighborhood Hits	55
SwissProt Accessions	P14859, Q5TBT7, Q6PK46, Q8NEU9, Q9BPV1	Gene names	POU2F1, OCT1, OTF1
Domain Architecture
Description	POU domain, class 2, transcription factor 1 (Octamer-binding transcription factor 1) (Oct-1) (OTF-1) (NF-A1).

PRB4S_HUMAN
θ value	6.88961 (rank : 2674)	NC score	0.073170 (rank : 1290)
Query Neighborhood Hits	2923	Target Neighborhood Hits	330	Shared Neighborhood Hits	161
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

PRGC2_MOUSE
θ value	6.88961 (rank : 2675)	NC score	0.011140 (rank : 2437)
Query Neighborhood Hits	2923	Target Neighborhood Hits	225	Shared Neighborhood Hits	78
SwissProt Accessions	Q8VHJ7, Q8C1C0	Gene names	Ppargc1b, Errl1, Pgc1, Pgc1b, Ppargc1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta protein) (PGC-1beta) (ERR ligand 1) (PPARGC-1-beta) (PGC-1-beta).

PRP18_HUMAN
θ value	6.88961 (rank : 2676)	NC score	0.005314 (rank : 2618)
Query Neighborhood Hits	2923	Target Neighborhood Hits	52	Shared Neighborhood Hits	25
SwissProt Accessions	Q99633, Q9BUI9	Gene names	PRPF18, HPRP18
Domain Architecture
Description	Pre-mRNA-splicing factor 18 (PRP18 homolog) (hPRP18).

PSCBP_MOUSE
θ value	6.88961 (rank : 2677)	NC score	0.012782 (rank : 2390)
Query Neighborhood Hits	2923	Target Neighborhood Hits	118	Shared Neighborhood Hits	27
SwissProt Accessions	Q91VY6, Q3TZH1, Q8R4T4, Q9QZA9	Gene names	Pscdbp
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (Cbp).

PSMD1_HUMAN
θ value	6.88961 (rank : 2678)	NC score	0.004919 (rank : 2641)
Query Neighborhood Hits	2923	Target Neighborhood Hits	42	Shared Neighborhood Hits	25
SwissProt Accessions	Q99460, Q53TI2, Q6GMU5, Q6P2P4, Q6PJM7, Q6PKG9, Q86VU1, Q8IV79	Gene names	PSMD1
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory subunit RPN2) (26S proteasome regulatory subunit S1) (26S proteasome subunit p112).

PSMD1_MOUSE
θ value	6.88961 (rank : 2679)	NC score	0.004550 (rank : 2659)
Query Neighborhood Hits	2923	Target Neighborhood Hits	42	Shared Neighborhood Hits	27
SwissProt Accessions	Q3TXS7	Gene names	Psmd1
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory subunit RPN2) (26S proteasome regulatory subunit S1).

PTN14_MOUSE
θ value	6.88961 (rank : 2680)	NC score	0.034327 (rank : 1944)
Query Neighborhood Hits	2923	Target Neighborhood Hits	142	Shared Neighborhood Hits	43
SwissProt Accessions	Q62130	Gene names	Ptpn14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36).

REXO1_HUMAN
θ value	6.88961 (rank : 2681)	NC score	0.025869 (rank : 2091)
Query Neighborhood Hits	2923	Target Neighborhood Hits	242	Shared Neighborhood Hits	121
SwissProt Accessions	Q8N1G1, Q9ULT2	Gene names	REXO1, ELOABP1, KIAA1138, TCEB3BP1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Elongin A-binding protein 1) (EloA-BP1) (Transcription elongation factor B polypeptide 3-binding protein 1).

REXO1_MOUSE
θ value	6.88961 (rank : 2682)	NC score	0.014144 (rank : 2351)
Query Neighborhood Hits	2923	Target Neighborhood Hits	166	Shared Neighborhood Hits	76
SwissProt Accessions	Q7TT28, Q3UMP1, Q69ZR0, Q6NSQ6, Q6PI95, Q9DA29	Gene names	Rexo1, Kiaa1138, Tceb3bp1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Transcription elongation factor B polypeptide 3-binding protein 1).

RGS9_MOUSE
θ value	6.88961 (rank : 2683)	NC score	-0.002763 (rank : 2928)
Query Neighborhood Hits	2923	Target Neighborhood Hits	65	Shared Neighborhood Hits	8
SwissProt Accessions	O54828, Q9Z0S0	Gene names	Rgs9
Domain Architecture
Description	Regulator of G-protein signaling 9 (RGS9).

RHG05_MOUSE
θ value	6.88961 (rank : 2684)	NC score	0.001097 (rank : 2797)
Query Neighborhood Hits	2923	Target Neighborhood Hits	165	Shared Neighborhood Hits	56
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

RNF17_MOUSE
θ value	6.88961 (rank : 2685)	NC score	0.003578 (rank : 2705)
Query Neighborhood Hits	2923	Target Neighborhood Hits	147	Shared Neighborhood Hits	54
SwissProt Accessions	Q99MV7	Gene names	Rnf17
Domain Architecture
Description	RING finger protein 17.

SAFB1_HUMAN
θ value	6.88961 (rank : 2686)	NC score	0.022795 (rank : 2151)
Query Neighborhood Hits	2923	Target Neighborhood Hits	493	Shared Neighborhood Hits	179
SwissProt Accessions	Q15424, O60406, Q59HH8	Gene names	SAFB, HAP, HET, SAFB1
Domain Architecture
Description	Scaffold attachment factor B (Scaffold attachment factor B1) (SAF-B) (HSP27 estrogen response element-TATA box-binding protein) (HSP27 ERE- TATA-binding protein).

SAPS1_HUMAN
θ value	6.88961 (rank : 2687)	NC score	0.029831 (rank : 2007)
Query Neighborhood Hits	2923	Target Neighborhood Hits	704	Shared Neighborhood Hits	253
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

SENP2_HUMAN
θ value	6.88961 (rank : 2688)	NC score	-0.000333 (rank : 2853)
Query Neighborhood Hits	2923	Target Neighborhood Hits	19	Shared Neighborhood Hits	6
SwissProt Accessions	Q9HC62, Q96SR2, Q9P2L5	Gene names	SENP2, KIAA1331
Domain Architecture
Description	Sentrin-specific protease 2 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP2) (SMT3-specific isopeptidase 2) (Smt3ip2) (Axam2).

SET1A_HUMAN
θ value	6.88961 (rank : 2689)	NC score	0.059897 (rank : 1444)
Query Neighborhood Hits	2923	Target Neighborhood Hits	690	Shared Neighborhood Hits	312
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SF01_HUMAN
θ value	6.88961 (rank : 2690)	NC score	0.032826 (rank : 1973)
Query Neighborhood Hits	2923	Target Neighborhood Hits	287	Shared Neighborhood Hits	134
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

SGOL1_MOUSE
θ value	6.88961 (rank : 2691)	NC score	0.006584 (rank : 2588)
Query Neighborhood Hits	2923	Target Neighborhood Hits	65	Shared Neighborhood Hits	30
SwissProt Accessions	Q9CXH7, Q3U4K4, Q588H1, Q8BKW2	Gene names	Sgol1, Sgo1
Domain Architecture	No domain graphic available
Description	Shugoshin-like 1.

SIRPD_HUMAN
θ value	6.88961 (rank : 2692)	NC score	0.040596 (rank : 1836)
Query Neighborhood Hits	2923	Target Neighborhood Hits	117	Shared Neighborhood Hits	65
SwissProt Accessions	Q9H106, Q5TFQ6	Gene names	SIRPD, PTPNS1L2
Domain Architecture
Description	Signal-regulatory protein delta precursor (Protein tyrosine phosphatase non-receptor type substrate 1-like 2).

SMP1L_MOUSE
θ value	6.88961 (rank : 2693)	NC score	-0.002351 (rank : 2915)
Query Neighborhood Hits	2923	Target Neighborhood Hits	70	Shared Neighborhood Hits	14
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

SOX8_HUMAN
θ value	6.88961 (rank : 2694)	NC score	-0.006463 (rank : 3000)
Query Neighborhood Hits	2923	Target Neighborhood Hits	100	Shared Neighborhood Hits	19
SwissProt Accessions	P57073, Q9NZW2	Gene names	SOX8
Domain Architecture
Description	Transcription factor SOX-8.

STAT1_MOUSE
θ value	6.88961 (rank : 2695)	NC score	0.006645 (rank : 2584)
Query Neighborhood Hits	2923	Target Neighborhood Hits	151	Shared Neighborhood Hits	78
SwissProt Accessions	P42225	Gene names	Stat1
Domain Architecture
Description	Signal transducer and activator of transcription 1.

SYEP_HUMAN
θ value	6.88961 (rank : 2696)	NC score	0.001035 (rank : 2799)
Query Neighborhood Hits	2923	Target Neighborhood Hits	70	Shared Neighborhood Hits	26
SwissProt Accessions	P07814	Gene names	EPRS, GLNS, PARS, QPRS
Domain Architecture
Description	Bifunctional aminoacyl-tRNA synthetase [Includes: Glutamyl-tRNA synthetase (EC 6.1.1.17) (Glutamate--tRNA ligase); Prolyl-tRNA synthetase (EC 6.1.1.15) (Proline--tRNA ligase)].

TAU_MOUSE
θ value	6.88961 (rank : 2697)	NC score	0.053779 (rank : 1621)
Query Neighborhood Hits	2923	Target Neighborhood Hits	502	Shared Neighborhood Hits	195
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TERF2_HUMAN
θ value	6.88961 (rank : 2698)	NC score	0.008033 (rank : 2538)
Query Neighborhood Hits	2923	Target Neighborhood Hits	102	Shared Neighborhood Hits	51
SwissProt Accessions	Q15554	Gene names	TERF2, TRF2
Domain Architecture
Description	Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein).

TIEG3_MOUSE
θ value	6.88961 (rank : 2699)	NC score	-0.029678 (rank : 3113)
Query Neighborhood Hits	2923	Target Neighborhood Hits	774	Shared Neighborhood Hits	85
SwissProt Accessions	Q8K1S5, Q8BI37	Gene names	Tieg3, Tieg2b
Domain Architecture
Description	Transforming growth factor-beta-inducible early growth response protein 3 (TGFB-inducible early growth response protein 3) (TIEG-3) (TGFB-inducible early growth response protein 2b).

TIP60_HUMAN
θ value	6.88961 (rank : 2700)	NC score	0.004767 (rank : 2650)
Query Neighborhood Hits	2923	Target Neighborhood Hits	90	Shared Neighborhood Hits	43
SwissProt Accessions	Q92993, O95624, Q13430, Q6GSE8, Q9BWK7	Gene names	HTATIP, TIP60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60) (HIV-1 Tat interactive protein) (cPLA(2)-interacting protein).

TIP60_MOUSE
θ value	6.88961 (rank : 2701)	NC score	0.004978 (rank : 2636)
Query Neighborhood Hits	2923	Target Neighborhood Hits	95	Shared Neighborhood Hits	44
SwissProt Accessions	Q8CHK4, Q8CGZ3, Q8CGZ4, Q8VIH0	Gene names	Htatip, Tip60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60).

TMEPA_MOUSE
θ value	6.88961 (rank : 2702)	NC score	0.001641 (rank : 2774)
Query Neighborhood Hits	2923	Target Neighborhood Hits	46	Shared Neighborhood Hits	17
SwissProt Accessions	Q9D7R2, Q9EQH9	Gene names	Tmepai, N4wbp4
Domain Architecture	No domain graphic available
Description	Transmembrane prostate androgen-induced protein (NEDD4 WW domain- binding protein 4).

TRAIP_HUMAN
θ value	6.88961 (rank : 2703)	NC score	0.038825 (rank : 1862)
Query Neighborhood Hits	2923	Target Neighborhood Hits	780	Shared Neighborhood Hits	293
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

TREF1_HUMAN
θ value	6.88961 (rank : 2704)	NC score	-0.008132 (rank : 3031)
Query Neighborhood Hits	2923	Target Neighborhood Hits	651	Shared Neighborhood Hits	102
SwissProt Accessions	Q96PN7, Q7Z6T2, Q7Z6T3, Q9NQ72, Q9NQ73, Q9NUN9	Gene names	TRERF1, RAPA, TREP132
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132) (Zinc finger protein rapa).

TRM1_HUMAN
θ value	6.88961 (rank : 2705)	NC score	0.003218 (rank : 2720)
Query Neighborhood Hits	2923	Target Neighborhood Hits	37	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NXH9, O76103, Q548Y5, Q8WVA6	Gene names	TRMT1
Domain Architecture
Description	N(2),N(2)-dimethylguanosine tRNA methyltransferase (EC 2.1.1.32) (tRNA(guanine-26,N(2)-N(2)) methyltransferase) (tRNA 2,2- dimethylguanosine-26 methyltransferase) (tRNA(m(2,2)G26)dimethyltransferase).

TTF1_MOUSE
θ value	6.88961 (rank : 2706)	NC score	0.025435 (rank : 2101)
Query Neighborhood Hits	2923	Target Neighborhood Hits	277	Shared Neighborhood Hits	144
SwissProt Accessions	Q62187, Q9JKK5	Gene names	Ttf1
Domain Architecture	No domain graphic available
Description	Transcription termination factor 1 (TTF-1) (TTF-I) (mTFF-I) (RNA polymerase I termination factor).

TVC4_MOUSE
θ value	6.88961 (rank : 2707)	NC score	-0.004923 (rank : 2974)
Query Neighborhood Hits	2923	Target Neighborhood Hits	246	Shared Neighborhood Hits	62
SwissProt Accessions	P06325	Gene names
Domain Architecture	No domain graphic available
Description	T-cell receptor gamma chain V region 5/10-13 precursor.

VPS53_MOUSE
θ value	6.88961 (rank : 2708)	NC score	0.007193 (rank : 2562)
Query Neighborhood Hits	2923	Target Neighborhood Hits	102	Shared Neighborhood Hits	60
SwissProt Accessions	Q8CCB4, Q8C7U0, Q8CIA1, Q9CX82, Q9D6T7	Gene names	Vps53
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 53.

WDR18_MOUSE
θ value	6.88961 (rank : 2709)	NC score	-0.013289 (rank : 3069)
Query Neighborhood Hits	2923	Target Neighborhood Hits	239	Shared Neighborhood Hits	17
SwissProt Accessions	Q4VBE8	Gene names	Wdr18
Domain Architecture	No domain graphic available
Description	WD repeat protein 18.

WNK2_HUMAN
θ value	6.88961 (rank : 2710)	NC score	0.656492 (rank : 534)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1407	Shared Neighborhood Hits	955
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

WWP2_HUMAN
θ value	6.88961 (rank : 2711)	NC score	-0.001786 (rank : 2903)
Query Neighborhood Hits	2923	Target Neighborhood Hits	177	Shared Neighborhood Hits	63
SwissProt Accessions	O00308, Q96CZ2, Q9BWN6	Gene names	WWP2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2) (Atrophin-1-interacting protein 2) (AIP2).

WWP2_MOUSE
θ value	6.88961 (rank : 2712)	NC score	-0.002803 (rank : 2931)
Query Neighborhood Hits	2923	Target Neighborhood Hits	118	Shared Neighborhood Hits	34
SwissProt Accessions	Q9DBH0, Q8BTG4, Q923F6	Gene names	Wwp2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2).

ZFY1_MOUSE
θ value	6.88961 (rank : 2713)	NC score	-0.029065 (rank : 3106)
Query Neighborhood Hits	2923	Target Neighborhood Hits	790	Shared Neighborhood Hits	81
SwissProt Accessions	P10925	Gene names	Zfy1, Zfy-1
Domain Architecture
Description	Zinc finger Y-chromosomal protein 1.

ZHX1_HUMAN
θ value	6.88961 (rank : 2714)	NC score	-0.003808 (rank : 2954)
Query Neighborhood Hits	2923	Target Neighborhood Hits	307	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UKY1, Q8IWD8	Gene names	ZHX1
Domain Architecture
Description	Zinc fingers and homeoboxes protein 1.

ZHX1_MOUSE
θ value	6.88961 (rank : 2715)	NC score	-0.002542 (rank : 2920)
Query Neighborhood Hits	2923	Target Neighborhood Hits	334	Shared Neighborhood Hits	47
SwissProt Accessions	P70121, Q8BQ68, Q8C6T4, Q8CJG3	Gene names	Zhx1
Domain Architecture
Description	Zinc fingers and homeoboxes protein 1.

ZN214_HUMAN
θ value	6.88961 (rank : 2716)	NC score	-0.029707 (rank : 3114)
Query Neighborhood Hits	2923	Target Neighborhood Hits	748	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UL59	Gene names	ZNF214, BAZ1
Domain Architecture
Description	Zinc finger protein 214 (BWSCR2-associated zinc-finger protein 1) (BAZ 1).

ZN365_HUMAN
θ value	6.88961 (rank : 2717)	NC score	0.022289 (rank : 2162)
Query Neighborhood Hits	2923	Target Neighborhood Hits	145	Shared Neighborhood Hits	82
SwissProt Accessions	Q70YC5, O94930, Q5HYE6, Q68SG8, Q6NSK2, Q6P9D4, Q70YC6, Q70YC7	Gene names	ZNF365, KIAA0844
Domain Architecture	No domain graphic available
Description	Protein ZNF365.

ZN449_HUMAN
θ value	6.88961 (rank : 2718)	NC score	-0.030271 (rank : 3124)
Query Neighborhood Hits	2923	Target Neighborhood Hits	758	Shared Neighborhood Hits	73
SwissProt Accessions	Q6P9G9, Q5JRZ8, Q6NZX2, Q8N3Q1, Q8TED7	Gene names	ZNF449, ZSCAN19
Domain Architecture	No domain graphic available
Description	Zinc finger protein 449 (Zinc finger and SCAN domain-containing protein 19).

ZWINT_MOUSE
θ value	6.88961 (rank : 2719)	NC score	0.050556 (rank : 1693)
Query Neighborhood Hits	2923	Target Neighborhood Hits	497	Shared Neighborhood Hits	258
SwissProt Accessions	Q9CQU5, Q3UYT8, Q91VI4, Q9D0W9	Gene names	Zwint, D10Ertd749e
Domain Architecture	No domain graphic available
Description	ZW10 interactor (ZW10-interacting protein 1) (Zwint-1).

ABCA2_MOUSE
θ value	8.99809 (rank : 2720)	NC score	-0.005980 (rank : 2994)
Query Neighborhood Hits	2923	Target Neighborhood Hits	124	Shared Neighborhood Hits	22
SwissProt Accessions	P41234	Gene names	Abca2, Abc2
Domain Architecture
Description	ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2).

ABEC4_MOUSE
θ value	8.99809 (rank : 2721)	NC score	0.001568 (rank : 2776)
Query Neighborhood Hits	2923	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	Q497M3	Gene names	Apobec4
Domain Architecture	No domain graphic available
Description	Putative C->U-editing enzyme APOBEC-4 (EC 3.5.4.-) (Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 4).

ACRO_HUMAN
θ value	8.99809 (rank : 2722)	NC score	-0.013952 (rank : 3072)
Query Neighborhood Hits	2923	Target Neighborhood Hits	291	Shared Neighborhood Hits	73
SwissProt Accessions	P10323, Q6ICK2	Gene names	ACR, ACRS
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

ADAM2_MOUSE
θ value	8.99809 (rank : 2723)	NC score	-0.000647 (rank : 2864)
Query Neighborhood Hits	2923	Target Neighborhood Hits	209	Shared Neighborhood Hits	32
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

AHTF1_MOUSE
θ value	8.99809 (rank : 2724)	NC score	0.016170 (rank : 2287)
Query Neighborhood Hits	2923	Target Neighborhood Hits	176	Shared Neighborhood Hits	77
SwissProt Accessions	Q8CJF7, Q8BVJ5, Q8VD55	Gene names	Ahctf1, Elys
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

AIP_MOUSE
θ value	8.99809 (rank : 2725)	NC score	-0.001122 (rank : 2883)
Query Neighborhood Hits	2923	Target Neighborhood Hits	51	Shared Neighborhood Hits	8
SwissProt Accessions	O08915	Gene names	Aip
Domain Architecture
Description	AH receptor-interacting protein (AIP) (Aryl-hydrocarbon receptor- interacting protein).

AKA10_HUMAN
θ value	8.99809 (rank : 2726)	NC score	0.001532 (rank : 2779)
Query Neighborhood Hits	2923	Target Neighborhood Hits	58	Shared Neighborhood Hits	10
SwissProt Accessions	O43572, Q96AJ7	Gene names	AKAP10
Domain Architecture
Description	A kinase anchor protein 10, mitochondrial precursor (Protein kinase A- anchoring protein 10) (PRKA10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2).

AKA10_MOUSE
θ value	8.99809 (rank : 2727)	NC score	0.001842 (rank : 2766)
Query Neighborhood Hits	2923	Target Neighborhood Hits	75	Shared Neighborhood Hits	19
SwissProt Accessions	O88845, Q5SUB5, Q5SUB7, Q7TPE7, Q8BQL6	Gene names	Akap10
Domain Architecture	No domain graphic available
Description	A kinase anchor protein 10, mitochondrial precursor (Protein kinase A- anchoring protein 10) (PRKA10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2).

AMD_HUMAN
θ value	8.99809 (rank : 2728)	NC score	-0.000261 (rank : 2850)
Query Neighborhood Hits	2923	Target Neighborhood Hits	22	Shared Neighborhood Hits	6
SwissProt Accessions	P19021, O95080, Q16252, Q16253, Q86U53, Q8WVC7, Q9UCG0	Gene names	PAM
Domain Architecture
Description	Peptidyl-glycine alpha-amidating monooxygenase precursor (PAM) [Includes: Peptidylglycine alpha-hydroxylating monooxygenase (EC 1.14.17.3) (PHM); Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (EC 4.3.2.5) (Peptidylamidoglycolate lyase) (PAL)].

ANR44_HUMAN
θ value	8.99809 (rank : 2729)	NC score	0.000638 (rank : 2819)
Query Neighborhood Hits	2923	Target Neighborhood Hits	318	Shared Neighborhood Hits	46
SwissProt Accessions	Q8N8A2, Q6P480, Q86VL5, Q8IZ72, Q9UFA4	Gene names	ANKRD44
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 44.

ANTR2_MOUSE
θ value	8.99809 (rank : 2730)	NC score	0.006633 (rank : 2585)
Query Neighborhood Hits	2923	Target Neighborhood Hits	26	Shared Neighborhood Hits	11
SwissProt Accessions	Q6DFX2, Q99L17	Gene names	Antxr2
Domain Architecture	No domain graphic available
Description	Anthrax toxin receptor 2 precursor.

ARMX2_MOUSE
θ value	8.99809 (rank : 2731)	NC score	0.010495 (rank : 2455)
Query Neighborhood Hits	2923	Target Neighborhood Hits	349	Shared Neighborhood Hits	114
SwissProt Accessions	Q6A058, Q9CXI9	Gene names	Armcx2, Kiaa0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2.

ARX_HUMAN
θ value	8.99809 (rank : 2732)	NC score	-0.019755 (rank : 3081)
Query Neighborhood Hits	2923	Target Neighborhood Hits	401	Shared Neighborhood Hits	38
SwissProt Accessions	Q96QS3	Gene names	ARX
Domain Architecture
Description	Homeobox protein ARX (Aristaless-related homeobox).

ASPP1_HUMAN
θ value	8.99809 (rank : 2733)	NC score	0.043352 (rank : 1789)
Query Neighborhood Hits	2923	Target Neighborhood Hits	956	Shared Neighborhood Hits	362
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

AUTS2_HUMAN
θ value	8.99809 (rank : 2734)	NC score	0.031381 (rank : 1992)
Query Neighborhood Hits	2923	Target Neighborhood Hits	342	Shared Neighborhood Hits	168
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

BAZ1B_MOUSE
θ value	8.99809 (rank : 2735)	NC score	0.012319 (rank : 2407)
Query Neighborhood Hits	2923	Target Neighborhood Hits	394	Shared Neighborhood Hits	182
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

BICD2_HUMAN
θ value	8.99809 (rank : 2736)	NC score	0.049479 (rank : 1714)
Query Neighborhood Hits	2923	Target Neighborhood Hits	856	Shared Neighborhood Hits	345
SwissProt Accessions	Q8TD16, O75181, Q5TBQ2, Q5TBQ3, Q96LH2, Q9BT84, Q9H561	Gene names	BICD2, KIAA0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

BIG1_HUMAN
θ value	8.99809 (rank : 2737)	NC score	-0.001578 (rank : 2898)
Query Neighborhood Hits	2923	Target Neighborhood Hits	76	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y6D6, Q9NV46, Q9UFV2, Q9UNL0	Gene names	ARFGEF1, ARFGEP1, BIG1
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Brefeldin A-inhibited GEP 1) (p200 ARF-GEP1) (p200 ARF guanine nucleotide exchange factor).

BORG3_MOUSE
θ value	8.99809 (rank : 2738)	NC score	0.000786 (rank : 2814)
Query Neighborhood Hits	2923	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z0X0, Q3SYK1, Q9QZT9	Gene names	Cdc42ep5, Borg3, Cep5
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 5 (Binder of Rho GTPases 3).

BUB1B_MOUSE
θ value	8.99809 (rank : 2739)	NC score	0.075382 (rank : 1278)
Query Neighborhood Hits	2923	Target Neighborhood Hits	202	Shared Neighborhood Hits	160
SwissProt Accessions	Q9Z1S0	Gene names	Bub1b, Mad3l
Domain Architecture
Description	Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (MAD3/BUB1-related protein kinase) (Mitotic checkpoint kinase MAD3L).

C1QBP_HUMAN
θ value	8.99809 (rank : 2740)	NC score	0.001752 (rank : 2768)
Query Neighborhood Hits	2923	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	Q07021, Q2HXR8, Q9NNY8	Gene names	C1QBP, GC1QBP, HABP1, SF2P32
Domain Architecture
Description	Complement component 1 Q subcomponent-binding protein, mitochondrial precursor (Glycoprotein gC1qBP) (C1qBP) (GC1q-R protein) (Hyaluronan- binding protein 1) (Mitochondrial matrix protein p32) (p33).

C8AP2_MOUSE
θ value	8.99809 (rank : 2741)	NC score	0.017747 (rank : 2244)
Query Neighborhood Hits	2923	Target Neighborhood Hits	405	Shared Neighborhood Hits	175
SwissProt Accessions	Q9WUF3, Q9CSW2	Gene names	Casp8ap2, Flash
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

CACP_MOUSE
θ value	8.99809 (rank : 2742)	NC score	-0.003578 (rank : 2952)
Query Neighborhood Hits	2923	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	P47934, Q923A6	Gene names	Crat
Domain Architecture
Description	Carnitine O-acetyltransferase (EC 2.3.1.7) (Carnitine acetylase) (CAT) (Carnitine acetyltransferase) (CrAT).

CAPS1_HUMAN
θ value	8.99809 (rank : 2743)	NC score	0.002909 (rank : 2729)
Query Neighborhood Hits	2923	Target Neighborhood Hits	86	Shared Neighborhood Hits	38
SwissProt Accessions	Q9ULU8, Q13339, Q6GQQ6, Q8N2Z5, Q8N3M7, Q8NFR0, Q96BC2	Gene names	CADPS, CAPS, CAPS1, KIAA1121
Domain Architecture	No domain graphic available
Description	Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1).

CAPS1_MOUSE
θ value	8.99809 (rank : 2744)	NC score	0.003924 (rank : 2681)
Query Neighborhood Hits	2923	Target Neighborhood Hits	93	Shared Neighborhood Hits	43
SwissProt Accessions	Q80TJ1, Q3TSP2, Q61374, Q6AXB4, Q6PGF0	Gene names	Cadps, Caps, Caps1, Kiaa1121
Domain Architecture	No domain graphic available
Description	Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1).

CD33_MOUSE
θ value	8.99809 (rank : 2745)	NC score	0.068864 (rank : 1315)
Query Neighborhood Hits	2923	Target Neighborhood Hits	45	Shared Neighborhood Hits	36
SwissProt Accessions	Q63994, Q63997	Gene names	Cd33
Domain Architecture
Description	Myeloid cell surface antigen CD33 precursor (Siglec-3).

CD79B_HUMAN
θ value	8.99809 (rank : 2746)	NC score	0.034659 (rank : 1937)
Query Neighborhood Hits	2923	Target Neighborhood Hits	143	Shared Neighborhood Hits	78
SwissProt Accessions	P40259, Q9BU06	Gene names	CD79B, B29, IGB
Domain Architecture
Description	B-cell antigen receptor complex-associated protein beta-chain precursor (B-cell-specific glycoprotein B29) (Immunoglobulin- associated B29 protein) (IG-beta) (CD79b antigen).

CELR2_HUMAN
θ value	8.99809 (rank : 2747)	NC score	0.001772 (rank : 2767)
Query Neighborhood Hits	2923	Target Neighborhood Hits	657	Shared Neighborhood Hits	118
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

CENG2_MOUSE
θ value	8.99809 (rank : 2748)	NC score	-0.010887 (rank : 3058)
Query Neighborhood Hits	2923	Target Neighborhood Hits	463	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

CEP63_HUMAN
θ value	8.99809 (rank : 2749)	NC score	0.057307 (rank : 1513)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1005	Shared Neighborhood Hits	387
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

CF150_HUMAN
θ value	8.99809 (rank : 2750)	NC score	0.018487 (rank : 2226)
Query Neighborhood Hits	2923	Target Neighborhood Hits	96	Shared Neighborhood Hits	46
SwissProt Accessions	Q8N884, Q32NC9, Q5SWL0, Q5SWL1, Q96E45	Gene names	C6orf150
Domain Architecture	No domain graphic available
Description	Protein C6orf150.

CF152_HUMAN
θ value	8.99809 (rank : 2751)	NC score	0.054858 (rank : 1579)
Query Neighborhood Hits	2923	Target Neighborhood Hits	704	Shared Neighborhood Hits	329
SwissProt Accessions	Q86VQ0, Q9BWX7	Gene names	C6orf152
Domain Architecture	No domain graphic available
Description	Protein C6orf152.

CHD4_HUMAN
θ value	8.99809 (rank : 2752)	NC score	0.005141 (rank : 2626)
Query Neighborhood Hits	2923	Target Neighborhood Hits	365	Shared Neighborhood Hits	129
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHSTB_MOUSE
θ value	8.99809 (rank : 2753)	NC score	-0.001114 (rank : 2882)
Query Neighborhood Hits	2923	Target Neighborhood Hits	21	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JME2, Q9JJS2	Gene names	Chst11
Domain Architecture	No domain graphic available
Description	Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O- sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4ST) (C4ST-1) (C4S-1).

CJ078_MOUSE
θ value	8.99809 (rank : 2754)	NC score	0.069650 (rank : 1309)
Query Neighborhood Hits	2923	Target Neighborhood Hits	559	Shared Neighborhood Hits	278
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

CNGB3_HUMAN
θ value	8.99809 (rank : 2755)	NC score	0.008036 (rank : 2537)
Query Neighborhood Hits	2923	Target Neighborhood Hits	206	Shared Neighborhood Hits	85
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

COFA1_HUMAN
θ value	8.99809 (rank : 2756)	NC score	0.015288 (rank : 2311)
Query Neighborhood Hits	2923	Target Neighborhood Hits	292	Shared Neighborhood Hits	100
SwissProt Accessions	P39059, Q5T6J4, Q9Y4W4	Gene names	COL15A1
Domain Architecture
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV) (Restin) (Related to endostatin)].

CP007_HUMAN
θ value	8.99809 (rank : 2757)	NC score	0.006605 (rank : 2587)
Query Neighborhood Hits	2923	Target Neighborhood Hits	85	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y2B5	Gene names	C16orf7, ATPBL
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf7 (Protein ATP-BL).

CS029_HUMAN
θ value	8.99809 (rank : 2758)	NC score	0.028621 (rank : 2030)
Query Neighborhood Hits	2923	Target Neighborhood Hits	329	Shared Neighborhood Hits	182
SwissProt Accessions	Q8WUQ7, O75229, Q7LE08, Q9BTA6, Q9Y5A4	Gene names	C19orf29
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 (NY-REN-24 antigen).

CSKI1_HUMAN
θ value	8.99809 (rank : 2759)	NC score	0.044042 (rank : 1778)
Query Neighborhood Hits	2923	Target Neighborhood Hits	997	Shared Neighborhood Hits	353
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CT102_HUMAN
θ value	8.99809 (rank : 2760)	NC score	0.023516 (rank : 2136)
Query Neighborhood Hits	2923	Target Neighborhood Hits	42	Shared Neighborhood Hits	32
SwissProt Accessions	Q96N03, Q5JWZ5, Q8ND45, Q9BR37	Gene names	C20orf102
Domain Architecture
Description	Protein C20orf102 precursor.

CYH2_HUMAN
θ value	8.99809 (rank : 2761)	NC score	0.003918 (rank : 2682)
Query Neighborhood Hits	2923	Target Neighborhood Hits	175	Shared Neighborhood Hits	54
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

CYH2_MOUSE
θ value	8.99809 (rank : 2762)	NC score	0.003739 (rank : 2693)
Query Neighborhood Hits	2923	Target Neighborhood Hits	171	Shared Neighborhood Hits	53
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

DAG1_HUMAN
θ value	8.99809 (rank : 2763)	NC score	0.017260 (rank : 2255)
Query Neighborhood Hits	2923	Target Neighborhood Hits	104	Shared Neighborhood Hits	64
SwissProt Accessions	Q14118	Gene names	DAG1
Domain Architecture
Description	Dystroglycan precursor (Dystrophin-associated glycoprotein 1) [Contains: Alpha-dystroglycan (Alpha-DG); Beta-dystroglycan (Beta- DG)].

DHX57_HUMAN
θ value	8.99809 (rank : 2764)	NC score	-0.001948 (rank : 2907)
Query Neighborhood Hits	2923	Target Neighborhood Hits	109	Shared Neighborhood Hits	27
SwissProt Accessions	Q6P158, Q53SI4, Q6P9G1, Q7Z6H3, Q8NG17, Q96M33	Gene names	DHX57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

DIAP1_MOUSE
θ value	8.99809 (rank : 2765)	NC score	0.038100 (rank : 1875)
Query Neighborhood Hits	2923	Target Neighborhood Hits	839	Shared Neighborhood Hits	365
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

DJC12_HUMAN
θ value	8.99809 (rank : 2766)	NC score	0.000646 (rank : 2818)
Query Neighborhood Hits	2923	Target Neighborhood Hits	141	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UKB3, Q9UKB2	Gene names	DNAJC12, JDP1
Domain Architecture
Description	DnaJ homolog subfamily C member 12 (J domain-containing protein 1).

DNJA4_MOUSE
θ value	8.99809 (rank : 2767)	NC score	-0.008399 (rank : 3037)
Query Neighborhood Hits	2923	Target Neighborhood Hits	87	Shared Neighborhood Hits	9
SwissProt Accessions	Q9JMC3, Q543S9, Q9CTD6, Q9CUD4	Gene names	Dnaja4
Domain Architecture
Description	DnaJ homolog subfamily A member 4 (MmDjA4).

DOCK4_HUMAN
θ value	8.99809 (rank : 2768)	NC score	0.009156 (rank : 2506)
Query Neighborhood Hits	2923	Target Neighborhood Hits	237	Shared Neighborhood Hits	99
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

DP13B_MOUSE
θ value	8.99809 (rank : 2769)	NC score	-0.000566 (rank : 2862)
Query Neighborhood Hits	2923	Target Neighborhood Hits	58	Shared Neighborhood Hits	21
SwissProt Accessions	Q8K3G9, Q99LT7	Gene names	Dip13b, Appl2, Dip3b
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 beta (Dip13 beta) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 2).

DSG1A_MOUSE
θ value	8.99809 (rank : 2770)	NC score	-0.010509 (rank : 3057)
Query Neighborhood Hits	2923	Target Neighborhood Hits	156	Shared Neighborhood Hits	34
SwissProt Accessions	Q61495, Q8CE03	Gene names	Dsg1a, Dsg1
Domain Architecture	No domain graphic available
Description	Desmoglein-1 alpha precursor (Dsg1-alpha) (Desmoglein-1) (Desmosomal glycoprotein I) (DG1) (DGI).

DTNB_HUMAN
θ value	8.99809 (rank : 2771)	NC score	0.010701 (rank : 2450)
Query Neighborhood Hits	2923	Target Neighborhood Hits	255	Shared Neighborhood Hits	133
SwissProt Accessions	O60941, O43782, O60881, O75538, Q9UE14, Q9UE15, Q9UE16	Gene names	DTNB
Domain Architecture
Description	Dystrobrevin beta (Beta-dystrobrevin) (DTN-B).

DYH5_HUMAN
θ value	8.99809 (rank : 2772)	NC score	0.007813 (rank : 2544)
Query Neighborhood Hits	2923	Target Neighborhood Hits	323	Shared Neighborhood Hits	158
SwissProt Accessions	Q8TE73, Q92860, Q96L74, Q9H5S7, Q9HCG9	Gene names	DNAH5, DNAHC5, KIAA1603
Domain Architecture	No domain graphic available
Description	Ciliary dynein heavy chain 5 (Axonemal beta dynein heavy chain 5) (HL1).

EEA1_MOUSE
θ value	8.99809 (rank : 2773)	NC score	0.054830 (rank : 1581)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1637	Shared Neighborhood Hits	543
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

ELF4_HUMAN
θ value	8.99809 (rank : 2774)	NC score	-0.000724 (rank : 2868)
Query Neighborhood Hits	2923	Target Neighborhood Hits	87	Shared Neighborhood Hits	29
SwissProt Accessions	Q99607, O60435	Gene names	ELF4, ELFR, MEF
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-4 (E74-like factor 4) (Myeloid Elf-1-like factor).

EME1_HUMAN
θ value	8.99809 (rank : 2775)	NC score	0.004568 (rank : 2657)
Query Neighborhood Hits	2923	Target Neighborhood Hits	31	Shared Neighborhood Hits	17
SwissProt Accessions	Q96AY2, Q96N62	Gene names	EME1, MMS4
Domain Architecture	No domain graphic available
Description	Crossover junction endonuclease EME1 (EC 3.1.22.-) (hMMS4).

ENW1_HUMAN
θ value	8.99809 (rank : 2776)	NC score	-0.001616 (rank : 2899)
Query Neighborhood Hits	2923	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UQF0, O95244, O95245, Q8NHY7, Q9NRZ2, Q9NZG3	Gene names	ERVWE1
Domain Architecture
Description	HERV-W_7q21.2 provirus ancestral Env polyprotein precursor (Envelope polyprotein gPr73) (HERV-7q Envelope protein) (HERV-W envelope protein) (Syncytin) (Syncytin-1) (Enverin) (Env-W) [Contains: Surface protein (SU) (gp50); Transmembrane protein (TM) (gp24)].

EPB42_MOUSE
θ value	8.99809 (rank : 2777)	NC score	-0.003674 (rank : 2953)
Query Neighborhood Hits	2923	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	P49222	Gene names	Epb42, Epb4.2
Domain Architecture
Description	Erythrocyte membrane protein band 4.2 (Erythrocyte protein 4.2) (P4.2).

EPC1_HUMAN
θ value	8.99809 (rank : 2778)	NC score	0.004260 (rank : 2669)
Query Neighborhood Hits	2923	Target Neighborhood Hits	60	Shared Neighborhood Hits	32
SwissProt Accessions	Q9H2F5, Q5VW54, Q5VW56, Q5VW58, Q8NAQ4, Q8NE21, Q96LF4, Q96RR6, Q9H7T7	Gene names	EPC1
Domain Architecture	No domain graphic available
Description	Enhancer of polycomb homolog 1.

ERC2_MOUSE
θ value	8.99809 (rank : 2779)	NC score	0.053289 (rank : 1631)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1166	Shared Neighborhood Hits	416
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

ETV1_HUMAN
θ value	8.99809 (rank : 2780)	NC score	-0.002664 (rank : 2927)
Query Neighborhood Hits	2923	Target Neighborhood Hits	107	Shared Neighborhood Hits	33
SwissProt Accessions	P50549, O75849, Q9UQ71, Q9Y636	Gene names	ETV1, ER81
Domain Architecture
Description	ETS translocation variant 1 (ER81 protein).

FHOD1_MOUSE
θ value	8.99809 (rank : 2781)	NC score	0.011394 (rank : 2430)
Query Neighborhood Hits	2923	Target Neighborhood Hits	217	Shared Neighborhood Hits	80
SwissProt Accessions	Q6P9Q4, Q8BMK2	Gene names	Fhod1, Fhos1
Domain Architecture	No domain graphic available
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

FMN1A_MOUSE
θ value	8.99809 (rank : 2782)	NC score	0.028370 (rank : 2041)
Query Neighborhood Hits	2923	Target Neighborhood Hits	423	Shared Neighborhood Hits	206
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

FXYD5_HUMAN
θ value	8.99809 (rank : 2783)	NC score	0.005145 (rank : 2625)
Query Neighborhood Hits	2923	Target Neighborhood Hits	30	Shared Neighborhood Hits	11
SwissProt Accessions	Q96DB9, Q6UW44, Q9HC34, Q9P039	Gene names	FXYD5, DYSAD, IWU1
Domain Architecture
Description	FXYD domain-containing ion transport regulator 5 precursor (Dysadherin).

GBRL1_HUMAN
θ value	8.99809 (rank : 2784)	NC score	-0.001192 (rank : 2887)
Query Neighborhood Hits	2923	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H0R8	Gene names	GABARAPL1, GEC1
Domain Architecture
Description	Gamma-aminobutyric acid receptor-associated protein-like 1 (GABA(A) receptor-associated protein-like 1) (Glandular epithelial cell protein 1) (GEC-1) (Early estrogen-regulated protein).

GBRL1_MOUSE
θ value	8.99809 (rank : 2785)	NC score	-0.001192 (rank : 2888)
Query Neighborhood Hits	2923	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R3R8, Q3TG14, Q9JJ97	Gene names	Gabarapl1, Gec1
Domain Architecture
Description	Gamma-aminobutyric acid receptor-associated protein-like 1 (GABA(A) receptor-associated protein-like 1) (Glandular epithelial cell protein 1) (GEC-1).

GGA1_HUMAN
θ value	8.99809 (rank : 2786)	NC score	0.009600 (rank : 2484)
Query Neighborhood Hits	2923	Target Neighborhood Hits	169	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UJY5, Q5TG07, Q9BW94, Q9UG00, Q9UGW0, Q9UGW1	Gene names	GGA1
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

GGA1_MOUSE
θ value	8.99809 (rank : 2787)	NC score	0.007484 (rank : 2555)
Query Neighborhood Hits	2923	Target Neighborhood Hits	128	Shared Neighborhood Hits	71
SwissProt Accessions	Q8R0H9, Q3U2N1	Gene names	Gga1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

GOGA3_HUMAN
θ value	8.99809 (rank : 2788)	NC score	0.056917 (rank : 1532)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1317	Shared Neighborhood Hits	455
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

GPI8_MOUSE
θ value	8.99809 (rank : 2789)	NC score	0.001266 (rank : 2791)
Query Neighborhood Hits	2923	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CXY9, Q8BH63	Gene names	Pigk
Domain Architecture
Description	GPI-anchor transamidase precursor (EC 3.-.-.-) (GPI transamidase) (Phosphatidylinositol-glycan biosynthesis class K protein) (PIG-K).

GTF2I_MOUSE
θ value	8.99809 (rank : 2790)	NC score	0.011002 (rank : 2444)
Query Neighborhood Hits	2923	Target Neighborhood Hits	72	Shared Neighborhood Hits	31
SwissProt Accessions	Q9ESZ8, O54700, O55030, O55031, Q8VHD1, Q8VHD2, Q8VHD3, Q8VHD4, Q9CSB5, Q9D9K9	Gene names	Gtf2i, Bap135, Diws1t
Domain Architecture
Description	General transcription factor II-I (GTFII-I) (TFII-I) (Bruton tyrosine kinase-associated protein 135) (BTK-associated protein 135) (BAP-135).

HB2S_MOUSE
θ value	8.99809 (rank : 2791)	NC score	-0.002334 (rank : 2914)
Query Neighborhood Hits	2923	Target Neighborhood Hits	202	Shared Neighborhood Hits	50
SwissProt Accessions	P06345	Gene names	H2-Ab1
Domain Architecture
Description	H-2 class II histocompatibility antigen, A-S beta chain precursor.

HB2X_HUMAN
θ value	8.99809 (rank : 2792)	NC score	0.000031 (rank : 2837)
Query Neighborhood Hits	2923	Target Neighborhood Hits	209	Shared Neighborhood Hits	56
SwissProt Accessions	P05538, Q29870, Q29871, Q29872, Q29873	Gene names	HLA-DQB2
Domain Architecture	No domain graphic available
Description	HLA class II histocompatibility antigen, DX beta chain precursor.

HCN2_HUMAN
θ value	8.99809 (rank : 2793)	NC score	0.014526 (rank : 2341)
Query Neighborhood Hits	2923	Target Neighborhood Hits	369	Shared Neighborhood Hits	145
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

HGS_MOUSE
θ value	8.99809 (rank : 2794)	NC score	0.013613 (rank : 2366)
Query Neighborhood Hits	2923	Target Neighborhood Hits	589	Shared Neighborhood Hits	220
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

HINT2_HUMAN
θ value	8.99809 (rank : 2795)	NC score	0.000382 (rank : 2828)
Query Neighborhood Hits	2923	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BX68	Gene names	HINT2
Domain Architecture	No domain graphic available
Description	Histidine triad nucleotide-binding protein 2 (EC 3.-.-.-) (HINT-2) (HINT-3) (HIT-17kDa) (PKCI-1-related HIT protein).

HSF1_MOUSE
θ value	8.99809 (rank : 2796)	NC score	0.010079 (rank : 2468)
Query Neighborhood Hits	2923	Target Neighborhood Hits	267	Shared Neighborhood Hits	113
SwissProt Accessions	P38532, O70462	Gene names	Hsf1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

HSP72_HUMAN
θ value	8.99809 (rank : 2797)	NC score	0.001246 (rank : 2792)
Query Neighborhood Hits	2923	Target Neighborhood Hits	85	Shared Neighborhood Hits	39
SwissProt Accessions	P54652, Q15508, Q9UE78	Gene names	HSPA2
Domain Architecture
Description	Heat shock-related 70 kDa protein 2 (Heat shock 70 kDa protein 2).

IASPP_MOUSE
θ value	8.99809 (rank : 2798)	NC score	0.035214 (rank : 1927)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1024	Shared Neighborhood Hits	291
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

IF31_HUMAN
θ value	8.99809 (rank : 2799)	NC score	0.011453 (rank : 2428)
Query Neighborhood Hits	2923	Target Neighborhood Hits	87	Shared Neighborhood Hits	53
SwissProt Accessions	O75822, Q9BUD2, Q9H8Q2, Q9UI65	Gene names	EIF3S1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 3 subunit 1 (eIF-3 alpha) (eIF3 p35) (eIF3j).

IFT20_HUMAN
θ value	8.99809 (rank : 2800)	NC score	0.005259 (rank : 2621)
Query Neighborhood Hits	2923	Target Neighborhood Hits	27	Shared Neighborhood Hits	13
SwissProt Accessions	Q8IY31, Q5GLZ2, Q9BUG5	Gene names	IFT20
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 20 homolog (Intraflagellar transport protein 20) (hIFT20).

IRTF_HUMAN
θ value	8.99809 (rank : 2801)	NC score	-0.003510 (rank : 2949)
Query Neighborhood Hits	2923	Target Neighborhood Hits	41	Shared Neighborhood Hits	11
SwissProt Accessions	Q00978	Gene names	ISGF3G, IRF9
Domain Architecture
Description	Transcriptional regulator ISGF3 subunit gamma (Interferon regulatory factor 9) (IRF-9) (IFN-alpha-responsive transcription factor subunit) (Interferon-stimulated gene factor 3 gamma) (ISGF3 p48 subunit) (ISGF- 3 gamma).

IRX3_MOUSE
θ value	8.99809 (rank : 2802)	NC score	-0.004316 (rank : 2960)
Query Neighborhood Hits	2923	Target Neighborhood Hits	303	Shared Neighborhood Hits	51
SwissProt Accessions	P81067	Gene names	Irx3, Irxb1
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-3 (Iroquois homeobox protein 3) (Homeodomain protein IRXB1).

ITA8_HUMAN
θ value	8.99809 (rank : 2803)	NC score	-0.006598 (rank : 3004)
Query Neighborhood Hits	2923	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	P53708, Q5VX94	Gene names	ITGA8
Domain Architecture
Description	Integrin alpha-8 precursor [Contains: Integrin alpha-8 heavy chain; Integrin alpha-8 light chain].

JHD3A_HUMAN
θ value	8.99809 (rank : 2804)	NC score	0.000973 (rank : 2802)
Query Neighborhood Hits	2923	Target Neighborhood Hits	78	Shared Neighborhood Hits	23
SwissProt Accessions	O75164, Q5VVB1	Gene names	JMJD2A, JHDM3A, JMJD2, KIAA0677
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3A (EC 1.14.11.-) (Jumonji domain-containing protein 2A).

K0310_HUMAN
θ value	8.99809 (rank : 2805)	NC score	0.029232 (rank : 2019)
Query Neighborhood Hits	2923	Target Neighborhood Hits	420	Shared Neighborhood Hits	150
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

K0317_MOUSE
θ value	8.99809 (rank : 2806)	NC score	-0.003247 (rank : 2940)
Query Neighborhood Hits	2923	Target Neighborhood Hits	43	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CHG5, Q6P9Q1, Q80YC4, Q8C5W5	Gene names	Kiaa0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

K1958_HUMAN
θ value	8.99809 (rank : 2807)	NC score	0.002920 (rank : 2728)
Query Neighborhood Hits	2923	Target Neighborhood Hits	76	Shared Neighborhood Hits	26
SwissProt Accessions	Q8N8K9, Q5T252, Q8TF43, Q96N02	Gene names	KIAA1958
Domain Architecture	No domain graphic available
Description	Protein KIAA1958.

KCNQ2_MOUSE
θ value	8.99809 (rank : 2808)	NC score	-0.004800 (rank : 2971)
Query Neighborhood Hits	2923	Target Neighborhood Hits	163	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Z351, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350	Gene names	Kcnq2, Kqt2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Potassium channel subunit alpha KvLQT2) (KQT-like 2).

KI13B_HUMAN
θ value	8.99809 (rank : 2809)	NC score	0.015306 (rank : 2310)
Query Neighborhood Hits	2923	Target Neighborhood Hits	492	Shared Neighborhood Hits	252
SwissProt Accessions	Q9NQT8, O75134, Q9BYJ6	Gene names	KIF13B, GAKIN, KIAA0639
Domain Architecture
Description	Kinesin-like protein KIF13B (Kinesin-like protein GAKIN).

KI21B_HUMAN
θ value	8.99809 (rank : 2810)	NC score	0.018124 (rank : 2234)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1017	Shared Neighborhood Hits	346
SwissProt Accessions	O75037, Q5T4J3	Gene names	KIF21B, KIAA0449
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B.

KIF23_HUMAN
θ value	8.99809 (rank : 2811)	NC score	0.033765 (rank : 1955)
Query Neighborhood Hits	2923	Target Neighborhood Hits	618	Shared Neighborhood Hits	316
SwissProt Accessions	Q02241	Gene names	KIF23, KNSL5, MKLP1
Domain Architecture
Description	Kinesin-like protein KIF23 (Mitotic kinesin-like protein 1) (Kinesin- like protein 5).

KINH_MOUSE
θ value	8.99809 (rank : 2812)	NC score	0.040236 (rank : 1842)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1082	Shared Neighborhood Hits	429
SwissProt Accessions	Q61768, O08711, Q61580	Gene names	Kif5b, Khcs, Kns1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

KLH10_HUMAN
θ value	8.99809 (rank : 2813)	NC score	-0.013020 (rank : 3068)
Query Neighborhood Hits	2923	Target Neighborhood Hits	194	Shared Neighborhood Hits	18
SwissProt Accessions	Q6JEL2, Q6NW28, Q96MC0	Gene names	KLHL10
Domain Architecture	No domain graphic available
Description	Kelch-like protein 10.

KLH10_MOUSE
θ value	8.99809 (rank : 2814)	NC score	-0.012907 (rank : 3066)
Query Neighborhood Hits	2923	Target Neighborhood Hits	192	Shared Neighborhood Hits	19
SwissProt Accessions	Q9D5V2, Q8BVM3, Q9DA07	Gene names	Klhl10
Domain Architecture	No domain graphic available
Description	Kelch-like protein 10.

KV1H_HUMAN
θ value	8.99809 (rank : 2815)	NC score	-0.002113 (rank : 2910)
Query Neighborhood Hits	2923	Target Neighborhood Hits	283	Shared Neighborhood Hits	85
SwissProt Accessions	P01600	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-I region Hau.

KV1R_HUMAN
θ value	8.99809 (rank : 2816)	NC score	-0.003164 (rank : 2938)
Query Neighborhood Hits	2923	Target Neighborhood Hits	253	Shared Neighborhood Hits	75
SwissProt Accessions	P01610	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-I region WEA.

KV1T_HUMAN
θ value	8.99809 (rank : 2817)	NC score	-0.003366 (rank : 2944)
Query Neighborhood Hits	2923	Target Neighborhood Hits	256	Shared Neighborhood Hits	75
SwissProt Accessions	P01612	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-I region Mev.

KV5K_MOUSE
θ value	8.99809 (rank : 2818)	NC score	-0.002597 (rank : 2923)
Query Neighborhood Hits	2923	Target Neighborhood Hits	214	Shared Neighborhood Hits	75
SwissProt Accessions	P01644	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-V region HP R16.7.

LAMA2_MOUSE
θ value	8.99809 (rank : 2819)	NC score	0.053552 (rank : 1626)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1198	Shared Neighborhood Hits	381
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMB1_MOUSE
θ value	8.99809 (rank : 2820)	NC score	0.041047 (rank : 1827)
Query Neighborhood Hits	2923	Target Neighborhood Hits	919	Shared Neighborhood Hits	303
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LIRA1_HUMAN
θ value	8.99809 (rank : 2821)	NC score	0.023743 (rank : 2131)
Query Neighborhood Hits	2923	Target Neighborhood Hits	83	Shared Neighborhood Hits	54
SwissProt Accessions	O75019, O75018	Gene names	LILRA1, LIR6
Domain Architecture
Description	Leukocyte immunoglobulin-like receptor subfamily A member 1 precursor (Leukocyte immunoglobulin-like receptor 6) (LIR-6) (CD85i antigen).

LIRA2_HUMAN
θ value	8.99809 (rank : 2822)	NC score	0.041924 (rank : 1815)
Query Neighborhood Hits	2923	Target Neighborhood Hits	100	Shared Neighborhood Hits	71
SwissProt Accessions	Q8N149, O75020	Gene names	LILRA2, ILT1, LIR7
Domain Architecture
Description	Leukocyte immunoglobulin-like receptor subfamily A member 2 precursor (Leukocyte immunoglobulin-like receptor 7) (LIR-7) (Immunoglobulin- like transcript 1) (ILT-1) (CD85h antigen).

LIRB2_HUMAN
θ value	8.99809 (rank : 2823)	NC score	0.029210 (rank : 2020)
Query Neighborhood Hits	2923	Target Neighborhood Hits	103	Shared Neighborhood Hits	65
SwissProt Accessions	Q8N423, O75017, Q8NHJ7, Q8NHJ8	Gene names	LILRB2, ILT4, LIR2, MIR10
Domain Architecture	No domain graphic available
Description	Leukocyte immunoglobulin-like receptor subfamily B member 2 precursor (Leukocyte immunoglobulin-like receptor 2) (LIR-2) (Immunoglobulin- like transcript 4) (ILT-4) (Monocyte/macrophage immunoglobulin-like receptor 10) (MIR-10) (CD85d antigen).

LRC17_HUMAN
θ value	8.99809 (rank : 2824)	NC score	0.029320 (rank : 2018)
Query Neighborhood Hits	2923	Target Neighborhood Hits	267	Shared Neighborhood Hits	66
SwissProt Accessions	Q8N6Y2, Q13288, Q6UWA7, Q75MG5	Gene names	LRRC17, P37NB
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 17 precursor (p37NB).

LRC41_HUMAN
θ value	8.99809 (rank : 2825)	NC score	0.006325 (rank : 2593)
Query Neighborhood Hits	2923	Target Neighborhood Hits	51	Shared Neighborhood Hits	18
SwissProt Accessions	Q15345, Q71RA8, Q9BSM0	Gene names	LRRC41, MUF1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 41 (Protein Muf1).

LRCH4_HUMAN
θ value	8.99809 (rank : 2826)	NC score	0.015032 (rank : 2317)
Query Neighborhood Hits	2923	Target Neighborhood Hits	305	Shared Neighborhood Hits	70
SwissProt Accessions	O75427, Q8WV85, Q96ID0	Gene names	LRCH4, LRN, LRRN4
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 4 (Leucine-rich neuronal protein).

LTBP4_MOUSE
θ value	8.99809 (rank : 2827)	NC score	0.021171 (rank : 2181)
Query Neighborhood Hits	2923	Target Neighborhood Hits	607	Shared Neighborhood Hits	154
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

LV1B_HUMAN
θ value	8.99809 (rank : 2828)	NC score	-0.005482 (rank : 2983)
Query Neighborhood Hits	2923	Target Neighborhood Hits	237	Shared Neighborhood Hits	61
SwissProt Accessions	P01700	Gene names
Domain Architecture	No domain graphic available
Description	Ig lambda chain V-I region HA.

MC4R_HUMAN
θ value	8.99809 (rank : 2829)	NC score	-0.034074 (rank : 3131)
Query Neighborhood Hits	2923	Target Neighborhood Hits	828	Shared Neighborhood Hits	5
SwissProt Accessions	P32245, Q16317, Q3MIJ6	Gene names	MC4R
Domain Architecture
Description	Melanocortin receptor 4 (MC4-R).

MC4R_MOUSE
θ value	8.99809 (rank : 2830)	NC score	-0.033796 (rank : 3130)
Query Neighborhood Hits	2923	Target Neighborhood Hits	816	Shared Neighborhood Hits	5
SwissProt Accessions	P56450, Q9EQM7	Gene names	Mc4r
Domain Architecture
Description	Melanocortin receptor 4 (MC4-R).

MEGF8_MOUSE
θ value	8.99809 (rank : 2831)	NC score	0.024440 (rank : 2121)
Query Neighborhood Hits	2923	Target Neighborhood Hits	520	Shared Neighborhood Hits	86
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF9_HUMAN
θ value	8.99809 (rank : 2832)	NC score	0.042201 (rank : 1808)
Query Neighborhood Hits	2923	Target Neighborhood Hits	557	Shared Neighborhood Hits	175
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MORC2_HUMAN
θ value	8.99809 (rank : 2833)	NC score	0.020598 (rank : 2192)
Query Neighborhood Hits	2923	Target Neighborhood Hits	207	Shared Neighborhood Hits	123
SwissProt Accessions	Q9Y6X9, Q9UF28, Q9Y6V2	Gene names	MORC2, KIAA0852, ZCWCC1
Domain Architecture
Description	MORC family CW-type zinc finger protein 2 (Zinc finger CW-type coiled- coil domain protein 1).

MRP5_MOUSE
θ value	8.99809 (rank : 2834)	NC score	-0.008466 (rank : 3039)
Query Neighborhood Hits	2923	Target Neighborhood Hits	99	Shared Neighborhood Hits	9
SwissProt Accessions	Q9R1X5, O88284	Gene names	Abcc5, Abcc5a, Mrp5
Domain Architecture
Description	Multidrug resistance-associated protein 5 (ATP-binding cassette sub- family C member 5) (ABC transporter MOAT-C) (SMRP).

MTRR_HUMAN
θ value	8.99809 (rank : 2835)	NC score	-0.001025 (rank : 2880)
Query Neighborhood Hits	2923	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UBK8, O60471	Gene names	MTRR
Domain Architecture
Description	Methionine synthase reductase, mitochondrial precursor (EC 1.16.1.8) (MSR).

MUC2_HUMAN
θ value	8.99809 (rank : 2836)	NC score	0.055155 (rank : 1574)
Query Neighborhood Hits	2923	Target Neighborhood Hits	906	Shared Neighborhood Hits	337
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

MYLIP_MOUSE
θ value	8.99809 (rank : 2837)	NC score	0.003614 (rank : 2703)
Query Neighborhood Hits	2923	Target Neighborhood Hits	139	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

MYO5C_HUMAN
θ value	8.99809 (rank : 2838)	NC score	0.053529 (rank : 1627)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1206	Shared Neighborhood Hits	440
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

MYSM1_MOUSE
θ value	8.99809 (rank : 2839)	NC score	0.007166 (rank : 2565)
Query Neighborhood Hits	2923	Target Neighborhood Hits	134	Shared Neighborhood Hits	59
SwissProt Accessions	Q69Z66, Q3TPV7, Q8BRP5, Q8C4N1	Gene names	Mysm1, Kiaa1915
Domain Architecture	No domain graphic available
Description	Protein MYSM1 (Myb-like, SWIRM and MPN domain-containing protein 1).

MYST1_HUMAN
θ value	8.99809 (rank : 2840)	NC score	0.001466 (rank : 2781)
Query Neighborhood Hits	2923	Target Neighborhood Hits	53	Shared Neighborhood Hits	33
SwissProt Accessions	Q9H7Z6, Q659G0, Q7LC17, Q8IY59, Q8WYB4, Q8WZ14, Q9HAC5, Q9NR35	Gene names	MYST1, MOF
Domain Architecture	No domain graphic available
Description	Probable histone acetyltransferase MYST1 (EC 2.3.1.48) (MYST protein 1) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1) (hMOF).

MYST1_MOUSE
θ value	8.99809 (rank : 2841)	NC score	0.001431 (rank : 2783)
Query Neighborhood Hits	2923	Target Neighborhood Hits	57	Shared Neighborhood Hits	34
SwissProt Accessions	Q9D1P2, Q3UIY0, Q8BJ69, Q8BJ76, Q8CI73	Gene names	Myst1, Mof
Domain Architecture	No domain graphic available
Description	Probable histone acetyltransferase MYST1 (EC 2.3.1.48) (MYST protein 1) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1).

NAT6_MOUSE
θ value	8.99809 (rank : 2842)	NC score	0.008859 (rank : 2511)
Query Neighborhood Hits	2923	Target Neighborhood Hits	36	Shared Neighborhood Hits	18
SwissProt Accessions	Q9R123, Q8QZY5, Q8R014, Q9ERM0	Gene names	Nat6, Fus2
Domain Architecture
Description	N-acetyltransferase 6 (EC 2.3.1.-) (Fus-2 protein) (Fusion 2 protein).

NHRF2_MOUSE
θ value	8.99809 (rank : 2843)	NC score	0.004931 (rank : 2639)
Query Neighborhood Hits	2923	Target Neighborhood Hits	194	Shared Neighborhood Hits	46
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

NKTR_HUMAN
θ value	8.99809 (rank : 2844)	NC score	0.013444 (rank : 2371)
Query Neighborhood Hits	2923	Target Neighborhood Hits	658	Shared Neighborhood Hits	241
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

NUFP2_HUMAN
θ value	8.99809 (rank : 2845)	NC score	0.002563 (rank : 2741)
Query Neighborhood Hits	2923	Target Neighborhood Hits	62	Shared Neighborhood Hits	17
SwissProt Accessions	Q7Z417, Q9P2M5	Gene names	NUFIP2, KIAA1321, PIG1
Domain Architecture	No domain graphic available
Description	Nuclear fragile X mental retardation-interacting protein 2 (FMRP- interacting protein 2) (82 kDa FMRP-interacting protein) (82-FIP) (Proliferation-inducing gene 1 protein).

OLR1_MOUSE
θ value	8.99809 (rank : 2846)	NC score	0.026132 (rank : 2084)
Query Neighborhood Hits	2923	Target Neighborhood Hits	596	Shared Neighborhood Hits	241
SwissProt Accessions	Q9EQ09	Gene names	Olr1, Lox1
Domain Architecture	No domain graphic available
Description	Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1) (Lectin-type oxidized LDL receptor 1) (Lectin-like oxidized LDL receptor 1) (Lectin-like oxLDL receptor 1) (LOX-1) [Contains: Oxidized low-density lipoprotein receptor 1, soluble form].

ORCT3_MOUSE
θ value	8.99809 (rank : 2847)	NC score	-0.005617 (rank : 2987)
Query Neighborhood Hits	2923	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	Q6A4L0, Q8VC89	Gene names	Slc22a13
Domain Architecture	No domain graphic available
Description	Organic cation transporter-like 3 (Solute carrier family 22 member 13).

PA2G4_HUMAN
θ value	8.99809 (rank : 2848)	NC score	0.000407 (rank : 2827)
Query Neighborhood Hits	2923	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UQ80, O43846, Q9UM59	Gene names	PA2G4, EBP1
Domain Architecture
Description	Proliferation-associated protein 2G4 (Cell cycle protein p38-2G4 homolog) (hG4-1) (ErbB3-binding protein 1).

PALB2_HUMAN
θ value	8.99809 (rank : 2849)	NC score	0.007194 (rank : 2561)
Query Neighborhood Hits	2923	Target Neighborhood Hits	117	Shared Neighborhood Hits	55
SwissProt Accessions	Q86YC2, Q8N7Y6, Q8ND31, Q9H6W1	Gene names	PALB2
Domain Architecture	No domain graphic available
Description	Partner and localizer of BRCA2.

PCDBE_HUMAN
θ value	8.99809 (rank : 2850)	NC score	-0.008653 (rank : 3041)
Query Neighborhood Hits	2923	Target Neighborhood Hits	154	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y5E9	Gene names	PCDHB14
Domain Architecture
Description	Protocadherin beta 14 precursor (PCDH-beta14).

PCDG9_HUMAN
θ value	8.99809 (rank : 2851)	NC score	-0.009147 (rank : 3051)
Query Neighborhood Hits	2923	Target Neighborhood Hits	158	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y5G4, Q9Y5C9	Gene names	PCDHGA9
Domain Architecture
Description	Protocadherin gamma A9 precursor (PCDH-gamma-A9).

PCDH7_HUMAN
θ value	8.99809 (rank : 2852)	NC score	-0.009081 (rank : 3048)
Query Neighborhood Hits	2923	Target Neighborhood Hits	175	Shared Neighborhood Hits	44
SwissProt Accessions	O60245, O60246, O60247	Gene names	PCDH7, BHPCDH
Domain Architecture
Description	Protocadherin-7 precursor (Brain-heart protocadherin) (BH-Pcdh).

PDIA1_HUMAN
θ value	8.99809 (rank : 2853)	NC score	-0.000496 (rank : 2856)
Query Neighborhood Hits	2923	Target Neighborhood Hits	56	Shared Neighborhood Hits	10
SwissProt Accessions	P07237, P30037, P32079, Q15205, Q6LDE5	Gene names	P4HB, PDI, PDIA1, PO4DB
Domain Architecture
Description	Protein disulfide-isomerase precursor (EC 5.3.4.1) (PDI) (Prolyl 4- hydroxylase subunit beta) (Cellular thyroid hormone-binding protein) (p55).

PHF22_HUMAN
θ value	8.99809 (rank : 2854)	NC score	0.007105 (rank : 2569)
Query Neighborhood Hits	2923	Target Neighborhood Hits	121	Shared Neighborhood Hits	46
SwissProt Accessions	Q96CB8, Q9HD71	Gene names	INTS12, PHF22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

PHF2_HUMAN
θ value	8.99809 (rank : 2855)	NC score	0.014128 (rank : 2353)
Query Neighborhood Hits	2923	Target Neighborhood Hits	208	Shared Neighborhood Hits	91
SwissProt Accessions	O75151, Q8N3K2, Q9Y6N4	Gene names	PHF2, KIAA0662
Domain Architecture
Description	PHD finger protein 2 (GRC5).

PHLB2_MOUSE
θ value	8.99809 (rank : 2856)	NC score	0.055604 (rank : 1566)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1016	Shared Neighborhood Hits	416
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

POGZ_MOUSE
θ value	8.99809 (rank : 2857)	NC score	-0.022662 (rank : 3085)
Query Neighborhood Hits	2923	Target Neighborhood Hits	765	Shared Neighborhood Hits	105
SwissProt Accessions	Q8BZH4, Q4VA94, Q80TZ8, Q8C0K1, Q8K294	Gene names	Pogz, Kiaa0461
Domain Architecture
Description	Pogo transposable element with ZNF domain.

PPIL4_HUMAN
θ value	8.99809 (rank : 2858)	NC score	-0.008970 (rank : 3046)
Query Neighborhood Hits	2923	Target Neighborhood Hits	264	Shared Neighborhood Hits	39
SwissProt Accessions	Q8WUA2, Q7Z3Q5	Gene names	PPIL4
Domain Architecture	No domain graphic available
Description	Peptidyl-prolyl cis-trans isomerase-like 4 (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin-like protein PPIL4).

PPIL4_MOUSE
θ value	8.99809 (rank : 2859)	NC score	-0.009425 (rank : 3052)
Query Neighborhood Hits	2923	Target Neighborhood Hits	232	Shared Neighborhood Hits	32
SwissProt Accessions	Q9CXG3, Q3TJX1, Q68FC7, Q9CT22	Gene names	Ppil4
Domain Architecture	No domain graphic available
Description	Peptidyl-prolyl cis-trans isomerase-like 4 (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin-like protein PPIL4).

PRPF3_MOUSE
θ value	8.99809 (rank : 2860)	NC score	0.002483 (rank : 2744)
Query Neighborhood Hits	2923	Target Neighborhood Hits	74	Shared Neighborhood Hits	29
SwissProt Accessions	Q922U1, Q3TJH4, Q9D6C6	Gene names	Prpf3
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3).

PTD4_HUMAN
θ value	8.99809 (rank : 2861)	NC score	0.000587 (rank : 2821)
Query Neighborhood Hits	2923	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NTK5, Q8NCI8, Q96CU1, Q96SV2, Q9P1D3, Q9UNY9, Q9Y6G4	Gene names	ames=PTD004, PRO2455
Domain Architecture
Description	Putative GTP-binding protein PTD004.

PTN23_MOUSE
θ value	8.99809 (rank : 2862)	NC score	0.056962 (rank : 1529)
Query Neighborhood Hits	2923	Target Neighborhood Hits	726	Shared Neighborhood Hits	339
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

RABE1_MOUSE
θ value	8.99809 (rank : 2863)	NC score	0.057979 (rank : 1492)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1105	Shared Neighborhood Hits	433
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

RAE1_MOUSE
θ value	8.99809 (rank : 2864)	NC score	0.001109 (rank : 2796)
Query Neighborhood Hits	2923	Target Neighborhood Hits	32	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QXG2, Q80UV8	Gene names	Chm, Rep1
Domain Architecture
Description	Rab proteins geranylgeranyltransferase component A 1 (Rab escort protein 1) (REP-1) (Choroideraemia protein homolog).

RBP2_HUMAN
θ value	8.99809 (rank : 2865)	NC score	-0.005751 (rank : 2990)
Query Neighborhood Hits	2923	Target Neighborhood Hits	249	Shared Neighborhood Hits	59
SwissProt Accessions	P49792, Q13074, Q15280, Q53TE2, Q59FH7	Gene names	RANBP2, NUP358
Domain Architecture
Description	Ran-binding protein 2 (RanBP2) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (358 kDa nucleoporin) (P270).

RGNEF_MOUSE
θ value	8.99809 (rank : 2866)	NC score	0.048793 (rank : 1720)
Query Neighborhood Hits	2923	Target Neighborhood Hits	641	Shared Neighborhood Hits	291
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

RL6_HUMAN
θ value	8.99809 (rank : 2867)	NC score	0.003985 (rank : 2677)
Query Neighborhood Hits	2923	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	Q02878, Q2M3Q3, Q8WW97	Gene names	RPL6
Domain Architecture
Description	60S ribosomal protein L6 (TAX-responsive enhancer element-binding protein 107) (TAXREB107) (Neoplasm-related protein C140).

RLF_HUMAN
θ value	8.99809 (rank : 2868)	NC score	-0.026623 (rank : 3093)
Query Neighborhood Hits	2923	Target Neighborhood Hits	775	Shared Neighborhood Hits	79
SwissProt Accessions	Q13129, Q9NU60	Gene names	RLF
Domain Architecture	No domain graphic available
Description	Zinc finger protein Rlf (Rearranged L-myc fusion gene protein) (Zn-15- related protein).

RNF37_HUMAN
θ value	8.99809 (rank : 2869)	NC score	-0.000016 (rank : 2839)
Query Neighborhood Hits	2923	Target Neighborhood Hits	82	Shared Neighborhood Hits	14
SwissProt Accessions	O94941	Gene names	UBOX5, KIAA0860, RNF37, UBCE7IP5
Domain Architecture
Description	RING finger protein 37 (Ubiquitin-conjugating enzyme 7-interacting protein 5) (U-box domain-containing protein 5).

S26A2_HUMAN
θ value	8.99809 (rank : 2870)	NC score	-0.002644 (rank : 2926)
Query Neighborhood Hits	2923	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	P50443	Gene names	SLC26A2, DTD, DTDST
Domain Architecture
Description	Sulfate transporter (Diastrophic dysplasia protein) (Solute carrier family 26 member 2).

S39A6_MOUSE
θ value	8.99809 (rank : 2871)	NC score	-0.001249 (rank : 2890)
Query Neighborhood Hits	2923	Target Neighborhood Hits	48	Shared Neighborhood Hits	9
SwissProt Accessions	Q8C145, Q7TPP9, Q7TQE0, Q8R518	Gene names	Slc39a6
Domain Architecture	No domain graphic available
Description	Zinc transporter SLC39A6 precursor (Solute carrier family 39 member 6) (Endoplasmic reticulum membrane-linked protein) (Ermelin).

SAS6_HUMAN
θ value	8.99809 (rank : 2872)	NC score	0.050840 (rank : 1683)
Query Neighborhood Hits	2923	Target Neighborhood Hits	791	Shared Neighborhood Hits	318
SwissProt Accessions	Q6UVJ0, Q8N3K0	Gene names	SASS6, SAS6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog (HsSAS-6).

SATT_MOUSE
θ value	8.99809 (rank : 2873)	NC score	-0.003474 (rank : 2947)
Query Neighborhood Hits	2923	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	O35874	Gene names	Slc1a4, Asct1
Domain Architecture
Description	Neutral amino acid transporter A (SATT) (Alanine/serine/cysteine/ threonine transporter) (ASCT1).

SCAP_HUMAN
θ value	8.99809 (rank : 2874)	NC score	-0.010321 (rank : 3056)
Query Neighborhood Hits	2923	Target Neighborhood Hits	368	Shared Neighborhood Hits	71
SwissProt Accessions	Q12770, Q8N2E0, Q8WUA1	Gene names	SCAP, KIAA0199
Domain Architecture
Description	Sterol regulatory element-binding protein cleavage-activating protein (SREBP cleavage-activating protein) (SCAP).

SCG2_MOUSE
θ value	8.99809 (rank : 2875)	NC score	0.005343 (rank : 2617)
Query Neighborhood Hits	2923	Target Neighborhood Hits	74	Shared Neighborhood Hits	33
SwissProt Accessions	Q03517, Q80Y79, Q9CW80	Gene names	Scg2, Chgc, Scg-2
Domain Architecture
Description	Secretogranin-2 precursor (Secretogranin II) (SgII) (Chromogranin C) [Contains: Secretoneurin (SN)].

SEM6C_MOUSE
θ value	8.99809 (rank : 2876)	NC score	0.004073 (rank : 2674)
Query Neighborhood Hits	2923	Target Neighborhood Hits	352	Shared Neighborhood Hits	109
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

SF3A1_MOUSE
θ value	8.99809 (rank : 2877)	NC score	0.029688 (rank : 2009)
Query Neighborhood Hits	2923	Target Neighborhood Hits	198	Shared Neighborhood Hits	113
SwissProt Accessions	Q8K4Z5, Q8C0M7, Q8C128, Q8C175, Q921T3	Gene names	Sf3a1
Domain Architecture	No domain graphic available
Description	Splicing factor 3 subunit 1 (SF3a120).

SG1D1_HUMAN
θ value	8.99809 (rank : 2878)	NC score	0.002868 (rank : 2731)
Query Neighborhood Hits	2923	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	O95968	Gene names	SCGB1D1, LIPHA
Domain Architecture
Description	Lipophilin-A precursor (Secretoglobin family 1D member 1).

SGIP1_HUMAN
θ value	8.99809 (rank : 2879)	NC score	0.028478 (rank : 2035)
Query Neighborhood Hits	2923	Target Neighborhood Hits	198	Shared Neighborhood Hits	94
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SLC2B_HUMAN
θ value	8.99809 (rank : 2880)	NC score	0.015580 (rank : 2301)
Query Neighborhood Hits	2923	Target Neighborhood Hits	214	Shared Neighborhood Hits	82
SwissProt Accessions	Q8NEV8, Q9Y4D6	Gene names	EXPH5, KIAA0624, SLAC2B
Domain Architecture	No domain graphic available
Description	Slp homolog lacking C2 domains b (Exophilin-5).

SMCA1_HUMAN
θ value	8.99809 (rank : 2881)	NC score	0.000959 (rank : 2804)
Query Neighborhood Hits	2923	Target Neighborhood Hits	105	Shared Neighborhood Hits	41
SwissProt Accessions	P28370, Q5JV41, Q5JV42	Gene names	SMARCA1, SNF2L, SNF2L1
Domain Architecture
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1).

SMG7_MOUSE
θ value	8.99809 (rank : 2882)	NC score	0.007913 (rank : 2543)
Query Neighborhood Hits	2923	Target Neighborhood Hits	113	Shared Neighborhood Hits	54
SwissProt Accessions	Q5RJH6, Q63ZW5, Q6ZQF3	Gene names	Smg7, Est1c, Kiaa0250
Domain Architecture	No domain graphic available
Description	Protein SMG7 (SMG-7 homolog) (EST1-like protein C).

SMRC1_HUMAN
θ value	8.99809 (rank : 2883)	NC score	0.020212 (rank : 2199)
Query Neighborhood Hits	2923	Target Neighborhood Hits	375	Shared Neighborhood Hits	196
SwissProt Accessions	Q92922, Q6P172, Q8IWH2	Gene names	SMARCC1, BAF155
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155).

SMRC2_HUMAN
θ value	8.99809 (rank : 2884)	NC score	0.023625 (rank : 2133)
Query Neighborhood Hits	2923	Target Neighborhood Hits	499	Shared Neighborhood Hits	208
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

SOX6_MOUSE
θ value	8.99809 (rank : 2885)	NC score	0.010159 (rank : 2464)
Query Neighborhood Hits	2923	Target Neighborhood Hits	341	Shared Neighborhood Hits	160
SwissProt Accessions	P40645, Q62250, Q9QWS5	Gene names	Sox6, Sox-6
Domain Architecture
Description	Transcription factor SOX-6 (SOX-LZ).

SPAG7_MOUSE
θ value	8.99809 (rank : 2886)	NC score	0.004125 (rank : 2673)
Query Neighborhood Hits	2923	Target Neighborhood Hits	21	Shared Neighborhood Hits	13
SwissProt Accessions	Q7TNE3, Q3TM27, Q80XJ8, Q8BK16	Gene names	Spag7
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 7.

SPR2E_MOUSE
θ value	8.99809 (rank : 2887)	NC score	0.024766 (rank : 2112)
Query Neighborhood Hits	2923	Target Neighborhood Hits	45	Shared Neighborhood Hits	19
SwissProt Accessions	O70556	Gene names	Sprr2e
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E.

SPT6H_HUMAN
θ value	8.99809 (rank : 2888)	NC score	0.008556 (rank : 2522)
Query Neighborhood Hits	2923	Target Neighborhood Hits	104	Shared Neighborhood Hits	40
SwissProt Accessions	Q7KZ85, Q15737, Q6GMQ4, Q7KYW9, Q7LDK4, Q8N526, Q92775, Q96AH3, Q9BTH9, Q9BTI2	Gene names	SUPT6H, KIAA0162, SPT6H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT6 (hSPT6) (Tat-cotransactivator 2 protein) (Tat-CT2 protein).

SUSD1_HUMAN
θ value	8.99809 (rank : 2889)	NC score	0.013370 (rank : 2373)
Query Neighborhood Hits	2923	Target Neighborhood Hits	285	Shared Neighborhood Hits	63
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

SYNJ1_MOUSE
θ value	8.99809 (rank : 2890)	NC score	0.038467 (rank : 1865)
Query Neighborhood Hits	2923	Target Neighborhood Hits	516	Shared Neighborhood Hits	240
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

SYNJ2_MOUSE
θ value	8.99809 (rank : 2891)	NC score	0.003780 (rank : 2691)
Query Neighborhood Hits	2923	Target Neighborhood Hits	87	Shared Neighborhood Hits	42
SwissProt Accessions	Q9D2G5, O35404, O88399, O88400, O88401, O88402, O88403, O88404	Gene names	Synj2, Kiaa0348
Domain Architecture
Description	Synaptojanin-2 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 2).

SYT12_MOUSE
θ value	8.99809 (rank : 2892)	NC score	0.004799 (rank : 2648)
Query Neighborhood Hits	2923	Target Neighborhood Hits	102	Shared Neighborhood Hits	16
SwissProt Accessions	Q920N7	Gene names	Syt12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

TAB3_HUMAN
θ value	8.99809 (rank : 2893)	NC score	0.012477 (rank : 2402)
Query Neighborhood Hits	2923	Target Neighborhood Hits	168	Shared Neighborhood Hits	67
SwissProt Accessions	Q8N5C8, Q6VQR0	Gene names	MAP3K7IP3, TAB3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3) (NF-kappa-B-activating protein 1).

TACC1_MOUSE
θ value	8.99809 (rank : 2894)	NC score	0.047261 (rank : 1737)
Query Neighborhood Hits	2923	Target Neighborhood Hits	667	Shared Neighborhood Hits	328
SwissProt Accessions	Q6Y685, Q6Y686	Gene names	Tacc1
Domain Architecture	No domain graphic available
Description	Transforming acidic coiled-coil-containing protein 1.

TACC3_HUMAN
θ value	8.99809 (rank : 2895)	NC score	0.046432 (rank : 1747)
Query Neighborhood Hits	2923	Target Neighborhood Hits	779	Shared Neighborhood Hits	341
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

TBC17_HUMAN
θ value	8.99809 (rank : 2896)	NC score	-0.000745 (rank : 2869)
Query Neighborhood Hits	2923	Target Neighborhood Hits	60	Shared Neighborhood Hits	20
SwissProt Accessions	Q9HA65	Gene names	TBC1D17
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 17.

TECT3_MOUSE
θ value	8.99809 (rank : 2897)	NC score	0.001331 (rank : 2788)
Query Neighborhood Hits	2923	Target Neighborhood Hits	33	Shared Neighborhood Hits	12
SwissProt Accessions	Q8R2Q6, Q8CDF3, Q9CRC5	Gene names	Tect3
Domain Architecture	No domain graphic available
Description	Tectonic-3 precursor.

TERF2_MOUSE
θ value	8.99809 (rank : 2898)	NC score	0.008800 (rank : 2512)
Query Neighborhood Hits	2923	Target Neighborhood Hits	128	Shared Neighborhood Hits	57
SwissProt Accessions	O35144	Gene names	Terf2, Trf2
Domain Architecture
Description	Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein).

TGFR2_MOUSE
θ value	8.99809 (rank : 2899)	NC score	0.509012 (rank : 835)
Query Neighborhood Hits	2923	Target Neighborhood Hits	748	Shared Neighborhood Hits	694
SwissProt Accessions	Q62312, Q63947	Gene names	Tgfbr2
Domain Architecture
Description	TGF-beta receptor type-2 precursor (EC 2.7.11.30) (TGF-beta receptor type II) (TGFR-2) (TGF-beta type II receptor).

TMEPA_HUMAN
θ value	8.99809 (rank : 2900)	NC score	0.000411 (rank : 2826)
Query Neighborhood Hits	2923	Target Neighborhood Hits	46	Shared Neighborhood Hits	15
SwissProt Accessions	Q969W9, Q5TDR6, Q96B72, Q9UJD3	Gene names	TMEPAI, PMEPA1, STAG1
Domain Architecture
Description	Transmembrane prostate androgen-induced protein (Solid tumor- associated 1 protein).

TNR1B_MOUSE
θ value	8.99809 (rank : 2901)	NC score	-0.002965 (rank : 2934)
Query Neighborhood Hits	2923	Target Neighborhood Hits	123	Shared Neighborhood Hits	21
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

TOP1_HUMAN
θ value	8.99809 (rank : 2902)	NC score	0.014144 (rank : 2352)
Query Neighborhood Hits	2923	Target Neighborhood Hits	207	Shared Neighborhood Hits	102
SwissProt Accessions	P11387, O43256, Q12855, Q12856, Q15610, Q5TFY3, Q9UJN0	Gene names	TOP1
Domain Architecture
Description	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I).

TOP1_MOUSE
θ value	8.99809 (rank : 2903)	NC score	0.011571 (rank : 2424)
Query Neighborhood Hits	2923	Target Neighborhood Hits	213	Shared Neighborhood Hits	95
SwissProt Accessions	Q04750	Gene names	Top1, Top-1
Domain Architecture
Description	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I).

TSH2_HUMAN
θ value	8.99809 (rank : 2904)	NC score	-0.002488 (rank : 2918)
Query Neighborhood Hits	2923	Target Neighborhood Hits	479	Shared Neighborhood Hits	85
SwissProt Accessions	Q9NRE2, Q4VXM4, Q6N003, Q8N260	Gene names	TSHZ2, C20orf17, TSH2, ZNF218
Domain Architecture	No domain graphic available
Description	Teashirt homolog 2 (Zinc finger protein 218) (Ovarian cancer-related protein 10-2) (OVC10-2).

TTLL4_HUMAN
θ value	8.99809 (rank : 2905)	NC score	-0.000532 (rank : 2859)
Query Neighborhood Hits	2923	Target Neighborhood Hits	79	Shared Neighborhood Hits	21
SwissProt Accessions	Q14679, Q8WW29	Gene names	TTLL4, KIAA0173
Domain Architecture
Description	Tubulin--tyrosine ligase-like protein 4.

TULP4_HUMAN
θ value	8.99809 (rank : 2906)	NC score	0.009346 (rank : 2499)
Query Neighborhood Hits	2923	Target Neighborhood Hits	426	Shared Neighborhood Hits	121
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

U2AFM_MOUSE
θ value	8.99809 (rank : 2907)	NC score	0.034738 (rank : 1934)
Query Neighborhood Hits	2923	Target Neighborhood Hits	543	Shared Neighborhood Hits	257
SwissProt Accessions	Q62377	Gene names	Zrsr2, U2af1-rs2, U2af1l2, U2af1rs2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2).

U5S1_HUMAN
θ value	8.99809 (rank : 2908)	NC score	-0.000534 (rank : 2860)
Query Neighborhood Hits	2923	Target Neighborhood Hits	33	Shared Neighborhood Hits	6
SwissProt Accessions	Q15029, Q9BUR0	Gene names	EFTUD2, KIAA0031, SNRP116
Domain Architecture
Description	116 kDa U5 small nuclear ribonucleoprotein component (U5 snRNP- specific protein, 116 kDa) (U5-116 kDa) (Elongation factor Tu GTP- binding domain protein 2) (hSNU114).

U5S1_MOUSE
θ value	8.99809 (rank : 2909)	NC score	-0.000486 (rank : 2855)
Query Neighborhood Hits	2923	Target Neighborhood Hits	37	Shared Neighborhood Hits	7
SwissProt Accessions	O08810	Gene names	Eftud2, Snrp116
Domain Architecture
Description	116 kDa U5 small nuclear ribonucleoprotein component (U5 snRNP- specific protein, 116 kDa) (U5-116 kDa) (Elongation factor Tu GTP- binding domain protein 2).

UBP14_HUMAN
θ value	8.99809 (rank : 2910)	NC score	-0.005382 (rank : 2981)
Query Neighborhood Hits	2923	Target Neighborhood Hits	89	Shared Neighborhood Hits	13
SwissProt Accessions	P54578	Gene names	USP14, TGT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

UBP42_HUMAN
θ value	8.99809 (rank : 2911)	NC score	0.007718 (rank : 2549)
Query Neighborhood Hits	2923	Target Neighborhood Hits	445	Shared Neighborhood Hits	149
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

UBP47_HUMAN
θ value	8.99809 (rank : 2912)	NC score	-0.005827 (rank : 2992)
Query Neighborhood Hits	2923	Target Neighborhood Hits	149	Shared Neighborhood Hits	28
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

WASF2_HUMAN
θ value	8.99809 (rank : 2913)	NC score	0.028714 (rank : 2029)
Query Neighborhood Hits	2923	Target Neighborhood Hits	280	Shared Neighborhood Hits	139
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

WASF2_MOUSE
θ value	8.99809 (rank : 2914)	NC score	0.035456 (rank : 1920)
Query Neighborhood Hits	2923	Target Neighborhood Hits	315	Shared Neighborhood Hits	169
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

WDR79_HUMAN
θ value	8.99809 (rank : 2915)	NC score	-0.004319 (rank : 2961)
Query Neighborhood Hits	2923	Target Neighborhood Hits	246	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BUR4, Q9NW09	Gene names	WDR79
Domain Architecture	No domain graphic available
Description	WD repeat protein 79.

YAP1_HUMAN
θ value	8.99809 (rank : 2916)	NC score	0.007609 (rank : 2551)
Query Neighborhood Hits	2923	Target Neighborhood Hits	173	Shared Neighborhood Hits	72
SwissProt Accessions	P46937	Gene names	YAP1, YAP65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

ZEP2_HUMAN
θ value	8.99809 (rank : 2917)	NC score	-0.020436 (rank : 3082)
Query Neighborhood Hits	2923	Target Neighborhood Hits	937	Shared Neighborhood Hits	158
SwissProt Accessions	P31629, Q02646, Q5THT5, Q9NS05	Gene names	HIVEP2
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 (HIV- EP2) (MHC-binding protein 2) (MBP-2).

ZFY16_MOUSE
θ value	8.99809 (rank : 2918)	NC score	-0.002055 (rank : 2909)
Query Neighborhood Hits	2923	Target Neighborhood Hits	108	Shared Neighborhood Hits	25
SwissProt Accessions	Q80U44, Q8BRD2, Q8CG97	Gene names	Zfyve16, Kiaa0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosomal- associated FYVE domain protein).

ZFYV9_HUMAN
θ value	8.99809 (rank : 2919)	NC score	-0.001074 (rank : 2881)
Query Neighborhood Hits	2923	Target Neighborhood Hits	134	Shared Neighborhood Hits	39
SwissProt Accessions	O95405, Q9UNE1, Q9Y5R7	Gene names	ZFYVE9, MADHIP, SARA, SMADIP
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Smad anchor for receptor activation) (Receptor activation anchor) (hSARA) (Novel serine protease) (NSP).

ZN175_HUMAN
θ value	8.99809 (rank : 2920)	NC score	-0.030095 (rank : 3121)
Query Neighborhood Hits	2923	Target Neighborhood Hits	774	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Y473	Gene names	ZNF175
Domain Architecture
Description	Zinc finger protein 175 (Zinc finger protein OTK18).

ZN200_HUMAN
θ value	8.99809 (rank : 2921)	NC score	-0.030512 (rank : 3125)
Query Neighborhood Hits	2923	Target Neighborhood Hits	720	Shared Neighborhood Hits	63
SwissProt Accessions	P98182, O15361	Gene names	ZNF200, ZNFMF
Domain Architecture
Description	Zinc finger protein 200.

ZN358_HUMAN
θ value	8.99809 (rank : 2922)	NC score	-0.028716 (rank : 3103)
Query Neighborhood Hits	2923	Target Neighborhood Hits	840	Shared Neighborhood Hits	113
SwissProt Accessions	Q9NW07, Q9BTM7	Gene names	ZNF358
Domain Architecture
Description	Zinc finger protein 358.

ZNF76_HUMAN
θ value	8.99809 (rank : 2923)	NC score	-0.030079 (rank : 3119)
Query Neighborhood Hits	2923	Target Neighborhood Hits	728	Shared Neighborhood Hits	66
SwissProt Accessions	P36508, Q9BQB2	Gene names	ZNF76
Domain Architecture	No domain graphic available
Description	Zinc finger protein 76.

AATK_HUMAN
θ value	θ > 10 (rank : 2924)	NC score	0.545024 (rank : 768)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1243	Shared Neighborhood Hits	857
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

AATK_MOUSE
θ value	θ > 10 (rank : 2925)	NC score	0.534661 (rank : 793)
Query Neighborhood Hits	2923	Target Neighborhood Hits	942	Shared Neighborhood Hits	777
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

ACV1B_HUMAN
θ value	θ > 10 (rank : 2926)	NC score	0.478535 (rank : 875)
Query Neighborhood Hits	2923	Target Neighborhood Hits	753	Shared Neighborhood Hits	701
SwissProt Accessions	P36896, Q15479, Q15480, Q15481, Q15482	Gene names	ACVR1B, ACVRLK4
Domain Architecture
Description	Activin receptor type 1B precursor (EC 2.7.11.30) (ACTR-IB) (Serine/threonine-protein kinase receptor R2) (SKR2) (Activin receptor-like kinase 4) (ALK-4).

ACV1B_MOUSE
θ value	θ > 10 (rank : 2927)	NC score	0.478927 (rank : 872)
Query Neighborhood Hits	2923	Target Neighborhood Hits	753	Shared Neighborhood Hits	700
SwissProt Accessions	Q61271	Gene names	Acvr1b
Domain Architecture
Description	Activin receptor type 1B precursor (EC 2.7.11.30) (ACTR-IB) (Serine/threonine-protein kinase receptor R2) (SKR2).

ACV1C_HUMAN
θ value	θ > 10 (rank : 2928)	NC score	0.427260 (rank : 912)
Query Neighborhood Hits	2923	Target Neighborhood Hits	709	Shared Neighborhood Hits	649
SwissProt Accessions	Q8NER5, Q4ZFZ8, Q86UL1, Q86UL2, Q8TBG2	Gene names	ACVR1C, ALK7
Domain Architecture	No domain graphic available
Description	Activin receptor type 1C precursor (EC 2.7.11.30) (ACTR-IC) (Activin receptor-like kinase 7) (ALK-7).

ACV1C_MOUSE
θ value	θ > 10 (rank : 2929)	NC score	0.429876 (rank : 908)
Query Neighborhood Hits	2923	Target Neighborhood Hits	715	Shared Neighborhood Hits	655
SwissProt Accessions	Q8K348	Gene names	Acvr1c, Alk7
Domain Architecture	No domain graphic available
Description	Activin receptor type 1C precursor (EC 2.7.11.30) (ACTR-IC) (Activin receptor-like kinase 7) (ALK-7).

ACVL1_HUMAN
θ value	θ > 10 (rank : 2930)	NC score	0.449502 (rank : 900)
Query Neighborhood Hits	2923	Target Neighborhood Hits	716	Shared Neighborhood Hits	665
SwissProt Accessions	P37023	Gene names	ACVRL1, ACVRLK1, ALK1
Domain Architecture
Description	Serine/threonine-protein kinase receptor R3 precursor (EC 2.7.11.30) (SKR3) (Activin receptor-like kinase 1) (ALK-1) (TGF-B superfamily receptor type I) (TSR-I).

ACVL1_MOUSE
θ value	θ > 10 (rank : 2931)	NC score	0.466384 (rank : 883)
Query Neighborhood Hits	2923	Target Neighborhood Hits	739	Shared Neighborhood Hits	689
SwissProt Accessions	Q61288, Q61289	Gene names	Acvrl1, Acvrlk1, Alk-1
Domain Architecture
Description	Serine/threonine-protein kinase receptor R3 precursor (EC 2.7.11.30) (SKR3) (Activin receptor-like kinase 1) (ALK-1) (TGF-B superfamily receptor type I) (TSR-I).

ACVR1_HUMAN
θ value	θ > 10 (rank : 2932)	NC score	0.497977 (rank : 844)
Query Neighborhood Hits	2923	Target Neighborhood Hits	760	Shared Neighborhood Hits	709
SwissProt Accessions	Q04771	Gene names	ACVR1, ACVRLK2
Domain Architecture
Description	Activin receptor type-1 precursor (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) (Serine/threonine-protein kinase receptor R1) (SKR1) (Activin receptor-like kinase 2) (ALK-2) (TGF-B superfamily receptor type I) (TSR-I).

ACVR1_MOUSE
θ value	θ > 10 (rank : 2933)	NC score	0.503617 (rank : 838)
Query Neighborhood Hits	2923	Target Neighborhood Hits	768	Shared Neighborhood Hits	714
SwissProt Accessions	P37172, Q3UDH5, Q91VF1	Gene names	Acvr1, Acvrlk2, Tgfb1
Domain Architecture
Description	Activin receptor type-1 precursor (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) (Serine/threonine-protein kinase receptor R1) (SKR1) (TGF-B superfamily receptor type I) (TSR-I) (TSK-7L).

AL2S2_HUMAN
θ value	θ > 10 (rank : 2934)	NC score	0.604258 (rank : 627)
Query Neighborhood Hits	2923	Target Neighborhood Hits	727	Shared Neighborhood Hits	686
SwissProt Accessions	Q9C0K7, Q5BKY7, Q9P1L0	Gene names	ALS2CR2, ILPIP
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ALS2CR2 (EC 2.7.11.1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein) (ILP- interacting protein) (CALS-21).

AL2S2_MOUSE
θ value	θ > 10 (rank : 2935)	NC score	0.595625 (rank : 648)
Query Neighborhood Hits	2923	Target Neighborhood Hits	709	Shared Neighborhood Hits	677
SwissProt Accessions	Q8K4T3, Q6P922, Q8BU86, Q8BXK0, Q8K4T2	Gene names	Als2cr2, Papk
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ALS2CR2 (EC 2.7.11.1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein homolog) (ILP-interacting protein homolog) (Polyploidy-associated protein kinase).

ALEX_HUMAN
θ value	θ > 10 (rank : 2936)	NC score	0.053160 (rank : 1634)
Query Neighborhood Hits	2923	Target Neighborhood Hits	361	Shared Neighborhood Hits	167
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

AMGO3_HUMAN
θ value	θ > 10 (rank : 2937)	NC score	0.060635 (rank : 1425)
Query Neighborhood Hits	2923	Target Neighborhood Hits	276	Shared Neighborhood Hits	100
SwissProt Accessions	Q86WK7, Q96JH6	Gene names	AMIGO3, ALI3, KIAA1851
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 3 precursor (AMIGO-3) (Alivin-3).

AMGO3_MOUSE
θ value	θ > 10 (rank : 2938)	NC score	0.057930 (rank : 1493)
Query Neighborhood Hits	2923	Target Neighborhood Hits	276	Shared Neighborhood Hits	95
SwissProt Accessions	Q8C2S7, Q6ZPH1, Q8CEB3	Gene names	Amigo3, Ali3, Kiaa1851
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 3 precursor (AMIGO-3) (Alivin-3).

AMHR2_HUMAN
θ value	θ > 10 (rank : 2939)	NC score	0.386842 (rank : 950)
Query Neighborhood Hits	2923	Target Neighborhood Hits	715	Shared Neighborhood Hits	621
SwissProt Accessions	Q16671, Q13762	Gene names	AMHR2, AMHR
Domain Architecture
Description	Anti-Muellerian hormone type-2 receptor precursor (EC 2.7.11.30) (Anti-Muellerian hormone type II receptor) (AMH type II receptor) (MIS type II receptor) (MISRII) (MRII).

ANKK1_HUMAN
θ value	θ > 10 (rank : 2940)	NC score	0.480684 (rank : 869)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1075	Shared Neighborhood Hits	765
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

ANKK1_MOUSE
θ value	θ > 10 (rank : 2941)	NC score	0.489842 (rank : 858)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1072	Shared Neighborhood Hits	769
SwissProt Accessions	Q8BZ25	Gene names	Ankk1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1).

ANPRA_HUMAN
θ value	θ > 10 (rank : 2942)	NC score	0.327405 (rank : 991)
Query Neighborhood Hits	2923	Target Neighborhood Hits	612	Shared Neighborhood Hits	507
SwissProt Accessions	P16066, Q6P4Q3	Gene names	NPR1, ANPRA
Domain Architecture
Description	Atrial natriuretic peptide receptor A precursor (ANP-A) (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor).

ANPRA_MOUSE
θ value	θ > 10 (rank : 2943)	NC score	0.326646 (rank : 992)
Query Neighborhood Hits	2923	Target Neighborhood Hits	600	Shared Neighborhood Hits	503
SwissProt Accessions	P18293	Gene names	Npr1, Npra
Domain Architecture
Description	Atrial natriuretic peptide receptor A precursor (ANP-A) (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor).

ANPRB_HUMAN
θ value	θ > 10 (rank : 2944)	NC score	0.350152 (rank : 977)
Query Neighborhood Hits	2923	Target Neighborhood Hits	646	Shared Neighborhood Hits	538
SwissProt Accessions	P20594, O60871, Q9UQ50	Gene names	NPR2, ANPRB
Domain Architecture
Description	Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor).

ANPRB_MOUSE
θ value	θ > 10 (rank : 2945)	NC score	0.328128 (rank : 990)
Query Neighborhood Hits	2923	Target Neighborhood Hits	607	Shared Neighborhood Hits	513
SwissProt Accessions	Q6VVW5, Q6VVW3, Q6VVW4, Q8CGA9	Gene names	Npr2
Domain Architecture	No domain graphic available
Description	Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor).

AVR2B_HUMAN
θ value	θ > 10 (rank : 2946)	NC score	0.498071 (rank : 842)
Query Neighborhood Hits	2923	Target Neighborhood Hits	748	Shared Neighborhood Hits	697
SwissProt Accessions	Q13705, Q4VAV0	Gene names	ACVR2B
Domain Architecture
Description	Activin receptor type 2B precursor (EC 2.7.11.30) (Activin receptor type IIB) (ACTR-IIB).

AVR2B_MOUSE
θ value	θ > 10 (rank : 2947)	NC score	0.497934 (rank : 845)
Query Neighborhood Hits	2923	Target Neighborhood Hits	749	Shared Neighborhood Hits	697
SwissProt Accessions	P27040	Gene names	Acvr2b
Domain Architecture
Description	Activin receptor type 2B precursor (EC 2.7.11.30) (Activin receptor type IIB) (ACTR-IIB).

AZI1_HUMAN
θ value	θ > 10 (rank : 2948)	NC score	0.059815 (rank : 1448)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1000	Shared Neighborhood Hits	399
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

BASP_HUMAN
θ value	θ > 10 (rank : 2949)	NC score	0.080636 (rank : 1260)
Query Neighborhood Hits	2923	Target Neighborhood Hits	321	Shared Neighborhood Hits	160
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BMPR2_HUMAN
θ value	θ > 10 (rank : 2950)	NC score	0.464240 (rank : 885)
Query Neighborhood Hits	2923	Target Neighborhood Hits	736	Shared Neighborhood Hits	667
SwissProt Accessions	Q13873, Q16569	Gene names	BMPR2, PPH1
Domain Architecture
Description	Bone morphogenetic protein receptor type-2 precursor (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II).

BMPR2_MOUSE
θ value	θ > 10 (rank : 2951)	NC score	0.462871 (rank : 888)
Query Neighborhood Hits	2923	Target Neighborhood Hits	738	Shared Neighborhood Hits	666
SwissProt Accessions	O35607	Gene names	Bmpr2
Domain Architecture
Description	Bone morphogenetic protein receptor type-2 precursor (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II) (BRK-3).

BMR1A_HUMAN
θ value	θ > 10 (rank : 2952)	NC score	0.492510 (rank : 851)
Query Neighborhood Hits	2923	Target Neighborhood Hits	759	Shared Neighborhood Hits	700
SwissProt Accessions	P36894, Q8NEN8	Gene names	BMPR1A, ACVRLK3, ALK3
Domain Architecture
Description	Bone morphogenetic protein receptor type IA precursor (EC 2.7.11.30) (Serine/threonine-protein kinase receptor R5) (SKR5) (Activin receptor-like kinase 3) (ALK-3) (CD292 antigen).

BMR1A_MOUSE
θ value	θ > 10 (rank : 2953)	NC score	0.491569 (rank : 855)
Query Neighborhood Hits	2923	Target Neighborhood Hits	758	Shared Neighborhood Hits	700
SwissProt Accessions	P36895	Gene names	Bmpr1a, Acvrlk3, Bmpr
Domain Architecture
Description	Bone morphogenetic protein receptor type IA precursor (EC 2.7.11.30) (Serine/threonine-protein kinase receptor R5) (SKR5) (Activin receptor-like kinase 3) (ALK-3) (BMP-2/BMP-4 receptor).

BMR1B_HUMAN
θ value	θ > 10 (rank : 2954)	NC score	0.478891 (rank : 873)
Query Neighborhood Hits	2923	Target Neighborhood Hits	760	Shared Neighborhood Hits	703
SwissProt Accessions	O00238, P78366	Gene names	BMPR1B
Domain Architecture
Description	Bone morphogenetic protein receptor type IB precursor (EC 2.7.11.30) (CDw293 antigen).

BMR1B_MOUSE
θ value	θ > 10 (rank : 2955)	NC score	0.480082 (rank : 870)
Query Neighborhood Hits	2923	Target Neighborhood Hits	758	Shared Neighborhood Hits	703
SwissProt Accessions	P36898, Q3TRF2	Gene names	Bmpr1b, Acvrlk6
Domain Architecture
Description	Bone morphogenetic protein receptor type IB precursor (EC 2.7.11.30) (Serine/threonine-protein kinase receptor R6) (SKR6) (Activin receptor-like kinase 6) (ALK-6).

BUB1_HUMAN
θ value	θ > 10 (rank : 2956)	NC score	0.342806 (rank : 983)
Query Neighborhood Hits	2923	Target Neighborhood Hits	543	Shared Neighborhood Hits	469
SwissProt Accessions	O43683, O43430, O43643, O60626	Gene names	BUB1, BUB1L
Domain Architecture
Description	Mitotic checkpoint serine/threonine-protein kinase BUB1 (EC 2.7.11.1) (hBUB1) (BUB1A).

CARD9_HUMAN
θ value	θ > 10 (rank : 2957)	NC score	0.052421 (rank : 1653)
Query Neighborhood Hits	2923	Target Neighborhood Hits	602	Shared Neighborhood Hits	284
SwissProt Accessions	Q9H257, Q5SXM6, Q9H854	Gene names	CARD9
Domain Architecture
Description	Caspase recruitment domain-containing protein 9 (hCARD9).

CCD13_HUMAN
θ value	θ > 10 (rank : 2958)	NC score	0.050543 (rank : 1694)
Query Neighborhood Hits	2923	Target Neighborhood Hits	721	Shared Neighborhood Hits	298
SwissProt Accessions	Q8IYE1	Gene names	CCDC13
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 13.

CCD19_HUMAN
θ value	θ > 10 (rank : 2959)	NC score	0.064255 (rank : 1352)
Query Neighborhood Hits	2923	Target Neighborhood Hits	639	Shared Neighborhood Hits	312
SwissProt Accessions	Q9UL16	Gene names	CCDC19, NESG1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 19 (Nasopharyngeal epithelium- specific protein 1).

CCD45_HUMAN
θ value	θ > 10 (rank : 2960)	NC score	0.051597 (rank : 1670)
Query Neighborhood Hits	2923	Target Neighborhood Hits	525	Shared Neighborhood Hits	285
SwissProt Accessions	Q96GE4, Q96M81	Gene names	CCDC45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

CCD62_HUMAN
θ value	θ > 10 (rank : 2961)	NC score	0.054840 (rank : 1580)
Query Neighborhood Hits	2923	Target Neighborhood Hits	631	Shared Neighborhood Hits	290
SwissProt Accessions	Q6P9F0, Q6ZVF2, Q86VJ0, Q9BYZ5	Gene names	CCDC62
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 60 (Aaa-protein) (Protein TSP- NY).

CCD96_HUMAN
θ value	θ > 10 (rank : 2962)	NC score	0.062201 (rank : 1390)
Query Neighborhood Hits	2923	Target Neighborhood Hits	595	Shared Neighborhood Hits	321
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CCDC6_HUMAN
θ value	θ > 10 (rank : 2963)	NC score	0.057212 (rank : 1518)
Query Neighborhood Hits	2923	Target Neighborhood Hits	723	Shared Neighborhood Hits	348
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

CCHCR_HUMAN
θ value	θ > 10 (rank : 2964)	NC score	0.052045 (rank : 1661)
Query Neighborhood Hits	2923	Target Neighborhood Hits	717	Shared Neighborhood Hits	307
SwissProt Accessions	Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2	Gene names	CCHCR1, C6orf18, HCR
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8).

CCHCR_MOUSE
θ value	θ > 10 (rank : 2965)	NC score	0.056970 (rank : 1528)
Query Neighborhood Hits	2923	Target Neighborhood Hits	932	Shared Neighborhood Hits	392
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

CD33_HUMAN
θ value	θ > 10 (rank : 2966)	NC score	0.073069 (rank : 1291)
Query Neighborhood Hits	2923	Target Neighborhood Hits	50	Shared Neighborhood Hits	44
SwissProt Accessions	P20138, Q8TD24	Gene names	CD33
Domain Architecture
Description	Myeloid cell surface antigen CD33 precursor (Siglec-3) (gp67).

CEA19_HUMAN
θ value	θ > 10 (rank : 2967)	NC score	0.052193 (rank : 1659)
Query Neighborhood Hits	2923	Target Neighborhood Hits	36	Shared Neighborhood Hits	26
SwissProt Accessions	Q7Z692, Q7Z693	Gene names	CEACAM19, CEAL1
Domain Architecture	No domain graphic available
Description	Carcinoembryonic antigen-related cell adhesion molecule 19 precursor (Carcinoembryonic antigen-like 1).

CEAM3_HUMAN
θ value	θ > 10 (rank : 2968)	NC score	0.084292 (rank : 1251)
Query Neighborhood Hits	2923	Target Neighborhood Hits	28	Shared Neighborhood Hits	23
SwissProt Accessions	P40198	Gene names	CEACAM3, CD66D, CGM1
Domain Architecture	No domain graphic available
Description	Carcinoembryonic antigen-related cell adhesion molecule 3 precursor (Carcinoembryonic antigen CGM1) (CD66d antigen).

CEAMA_MOUSE
θ value	θ > 10 (rank : 2969)	NC score	0.084301 (rank : 1250)
Query Neighborhood Hits	2923	Target Neighborhood Hits	41	Shared Neighborhood Hits	37
SwissProt Accessions	Q61400, Q99LD6, Q9D329	Gene names	Ceacam10, Cea10
Domain Architecture	No domain graphic available
Description	Carcinoembryonic antigen-related cell adhesion molecule 10 precursor (CEA-related cell adhesion molecule 10) (Carcinoembryonic antigen 10) (CEA10).

CEP55_MOUSE
θ value	θ > 10 (rank : 2970)	NC score	0.050394 (rank : 1697)
Query Neighborhood Hits	2923	Target Neighborhood Hits	693	Shared Neighborhood Hits	317
SwissProt Accessions	Q8BT07, Q8C2J0, Q8K2I8, Q8R2Y4, Q9DBZ8	Gene names	Cep55
Domain Architecture	No domain graphic available
Description	Centrosome protein 55.

CF060_HUMAN
θ value	θ > 10 (rank : 2971)	NC score	0.060933 (rank : 1416)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1270	Shared Neighborhood Hits	469
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

CHIN_HUMAN
θ value	θ > 10 (rank : 2972)	NC score	0.059114 (rank : 1467)
Query Neighborhood Hits	2923	Target Neighborhood Hits	227	Shared Neighborhood Hits	72
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIN_MOUSE
θ value	θ > 10 (rank : 2973)	NC score	0.059599 (rank : 1455)
Query Neighborhood Hits	2923	Target Neighborhood Hits	229	Shared Neighborhood Hits	72
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIO_HUMAN
θ value	θ > 10 (rank : 2974)	NC score	0.060329 (rank : 1432)
Query Neighborhood Hits	2923	Target Neighborhood Hits	220	Shared Neighborhood Hits	71
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

CHIO_MOUSE
θ value	θ > 10 (rank : 2975)	NC score	0.055058 (rank : 1575)
Query Neighborhood Hits	2923	Target Neighborhood Hits	130	Shared Neighborhood Hits	45
SwissProt Accessions	Q80XD1, Q9D9W2, Q9ER57	Gene names	Chn2, Arhgap3, Bch
Domain Architecture	No domain graphic available
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

CK5P2_MOUSE
θ value	θ > 10 (rank : 2976)	NC score	0.057409 (rank : 1508)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1151	Shared Neighborhood Hits	446
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

CN145_MOUSE
θ value	θ > 10 (rank : 2977)	NC score	0.052553 (rank : 1646)
Query Neighborhood Hits	2923	Target Neighborhood Hits	916	Shared Neighborhood Hits	361
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

CNTRB_HUMAN
θ value	θ > 10 (rank : 2978)	NC score	0.054973 (rank : 1578)
Query Neighborhood Hits	2923	Target Neighborhood Hits	690	Shared Neighborhood Hits	300
SwissProt Accessions	Q8N137, Q331K3, Q69YV7, Q8NCB8, Q8WXV3, Q96CQ7, Q9C060	Gene names	CNTROB, LIP8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

CP135_HUMAN
θ value	θ > 10 (rank : 2979)	NC score	0.056532 (rank : 1544)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1290	Shared Neighborhood Hits	444
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CT2NL_HUMAN
θ value	θ > 10 (rank : 2980)	NC score	0.056597 (rank : 1543)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1059	Shared Neighborhood Hits	433
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

CT2NL_MOUSE
θ value	θ > 10 (rank : 2981)	NC score	0.055196 (rank : 1572)
Query Neighborhood Hits	2923	Target Neighborhood Hits	902	Shared Neighborhood Hits	405
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

CYLN2_MOUSE
θ value	θ > 10 (rank : 2982)	NC score	0.055177 (rank : 1573)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1002	Shared Neighborhood Hits	388
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

DCX_HUMAN
θ value	θ > 10 (rank : 2983)	NC score	0.067187 (rank : 1328)
Query Neighborhood Hits	2923	Target Neighborhood Hits	141	Shared Neighborhood Hits	59
SwissProt Accessions	O43602, O43911	Gene names	DCX, DBCN, LISX
Domain Architecture
Description	Neuronal migration protein doublecortin (Lissencephalin-X) (Lis-X) (Doublin).

DCX_MOUSE
θ value	θ > 10 (rank : 2984)	NC score	0.063029 (rank : 1373)
Query Neighborhood Hits	2923	Target Neighborhood Hits	124	Shared Neighborhood Hits	39
SwissProt Accessions	O88809	Gene names	Dcx, Dcn
Domain Architecture
Description	Neuronal migration protein doublecortin (Lissencephalin-X) (Lis-X) (Doublin).

DGKD_HUMAN
θ value	θ > 10 (rank : 2985)	NC score	0.063767 (rank : 1362)
Query Neighborhood Hits	2923	Target Neighborhood Hits	231	Shared Neighborhood Hits	92
SwissProt Accessions	Q16760, Q14158, Q6PK55, Q8NG53	Gene names	DGKD, KIAA0145
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase delta (EC 2.7.1.107) (Diglyceride kinase delta) (DGK-delta) (DAG kinase delta) (130 kDa diacylglycerol kinase).

DGKH_HUMAN
θ value	θ > 10 (rank : 2986)	NC score	0.058917 (rank : 1471)
Query Neighborhood Hits	2923	Target Neighborhood Hits	255	Shared Neighborhood Hits	92
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

DGKK_HUMAN
θ value	θ > 10 (rank : 2987)	NC score	0.056906 (rank : 1534)
Query Neighborhood Hits	2923	Target Neighborhood Hits	378	Shared Neighborhood Hits	184
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

DGKQ_HUMAN
θ value	θ > 10 (rank : 2988)	NC score	0.054430 (rank : 1592)
Query Neighborhood Hits	2923	Target Neighborhood Hits	131	Shared Neighborhood Hits	42
SwissProt Accessions	P52824	Gene names	DGKQ, DAGK4
Domain Architecture
Description	Diacylglycerol kinase theta (EC 2.7.1.107) (Diglyceride kinase theta) (DGK-theta) (DAG kinase theta).

E2AK1_MOUSE
θ value	θ > 10 (rank : 2989)	NC score	0.667085 (rank : 506)
Query Neighborhood Hits	2923	Target Neighborhood Hits	821	Shared Neighborhood Hits	766
SwissProt Accessions	Q9Z2R9, Q8C024, Q8K123, Q9CTP5, Q9D601	Gene names	Eif2ak1, Hri
Domain Architecture
Description	Eukaryotic translation initiation factor 2-alpha kinase 1 (EC 2.7.11.1) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Heme-controlled repressor) (HCR) (Hemin-sensitive initiation factor 2-alpha kinase).

E2AK4_MOUSE
θ value	θ > 10 (rank : 2990)	NC score	0.647605 (rank : 555)
Query Neighborhood Hits	2923	Target Neighborhood Hits	984	Shared Neighborhood Hits	844
SwissProt Accessions	Q9QZ05, Q6GQT4, Q6ZPT5, Q8C5S0, Q8CIF5, Q9CT30, Q9CUV9, Q9ESB6, Q9ESB7, Q9ESB8	Gene names	Eif2ak4, Gcn2, Kiaa1338
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 2-alpha kinase 4 (EC 2.7.11.1) (GCN2-like protein) (mGCN2).

ENAH_HUMAN
θ value	θ > 10 (rank : 2991)	NC score	0.058245 (rank : 1488)
Query Neighborhood Hits	2923	Target Neighborhood Hits	784	Shared Neighborhood Hits	389
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

ENAH_MOUSE
θ value	θ > 10 (rank : 2992)	NC score	0.061056 (rank : 1413)
Query Neighborhood Hits	2923	Target Neighborhood Hits	919	Shared Neighborhood Hits	429
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

ERBB3_HUMAN
θ value	θ > 10 (rank : 2993)	NC score	0.522480 (rank : 815)
Query Neighborhood Hits	2923	Target Neighborhood Hits	918	Shared Neighborhood Hits	745
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

ERBB3_MOUSE
θ value	θ > 10 (rank : 2994)	NC score	0.524135 (rank : 808)
Query Neighborhood Hits	2923	Target Neighborhood Hits	898	Shared Neighborhood Hits	739
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

GAS8_HUMAN
θ value	θ > 10 (rank : 2995)	NC score	0.058802 (rank : 1475)
Query Neighborhood Hits	2923	Target Neighborhood Hits	819	Shared Neighborhood Hits	357
SwissProt Accessions	O95995	Gene names	GAS8, GAS11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

GAS8_MOUSE
θ value	θ > 10 (rank : 2996)	NC score	0.059778 (rank : 1450)
Query Neighborhood Hits	2923	Target Neighborhood Hits	622	Shared Neighborhood Hits	298
SwissProt Accessions	Q60779, Q99L71	Gene names	Gas8, Gas11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

GCC1_HUMAN
θ value	θ > 10 (rank : 2997)	NC score	0.053141 (rank : 1635)
Query Neighborhood Hits	2923	Target Neighborhood Hits	887	Shared Neighborhood Hits	347
SwissProt Accessions	Q96CN9, Q9H6N7	Gene names	GCC1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

GCC1_MOUSE
θ value	θ > 10 (rank : 2998)	NC score	0.050621 (rank : 1689)
Query Neighborhood Hits	2923	Target Neighborhood Hits	777	Shared Neighborhood Hits	328
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

GOGA5_HUMAN
θ value	θ > 10 (rank : 2999)	NC score	0.054189 (rank : 1606)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1168	Shared Neighborhood Hits	431
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

GOGA5_MOUSE
θ value	θ > 10 (rank : 3000)	NC score	0.057210 (rank : 1519)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1434	Shared Neighborhood Hits	499
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

GOGA6_HUMAN
θ value	θ > 10 (rank : 3001)	NC score	0.058443 (rank : 1481)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1007	Shared Neighborhood Hits	401
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

GRAP1_MOUSE
θ value	θ > 10 (rank : 3002)	NC score	0.059331 (rank : 1461)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1234	Shared Neighborhood Hits	452
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

GRAP2_HUMAN
θ value	θ > 10 (rank : 3003)	NC score	0.053696 (rank : 1624)
Query Neighborhood Hits	2923	Target Neighborhood Hits	304	Shared Neighborhood Hits	81
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

GRAP2_MOUSE
θ value	θ > 10 (rank : 3004)	NC score	0.052520 (rank : 1649)
Query Neighborhood Hits	2923	Target Neighborhood Hits	297	Shared Neighborhood Hits	79
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

GRAP_HUMAN
θ value	θ > 10 (rank : 3005)	NC score	0.057178 (rank : 1520)
Query Neighborhood Hits	2923	Target Neighborhood Hits	307	Shared Neighborhood Hits	88
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

GRAP_MOUSE
θ value	θ > 10 (rank : 3006)	NC score	0.056089 (rank : 1553)
Query Neighborhood Hits	2923	Target Neighborhood Hits	309	Shared Neighborhood Hits	85
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

GRB2_HUMAN
θ value	θ > 10 (rank : 3007)	NC score	0.054142 (rank : 1607)
Query Neighborhood Hits	2923	Target Neighborhood Hits	310	Shared Neighborhood Hits	82
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
θ value	θ > 10 (rank : 3008)	NC score	0.054118 (rank : 1609)
Query Neighborhood Hits	2923	Target Neighborhood Hits	312	Shared Neighborhood Hits	82
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

GRP3_HUMAN
θ value	θ > 10 (rank : 3009)	NC score	0.080110 (rank : 1263)
Query Neighborhood Hits	2923	Target Neighborhood Hits	131	Shared Neighborhood Hits	48
SwissProt Accessions	Q8IV61, O94931	Gene names	RASGRP3, GRP3, KIAA0846
Domain Architecture
Description	RAS guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1).

GSCR1_HUMAN
θ value	θ > 10 (rank : 3010)	NC score	0.062529 (rank : 1385)
Query Neighborhood Hits	2923	Target Neighborhood Hits	674	Shared Neighborhood Hits	292
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

GUC2C_HUMAN
θ value	θ > 10 (rank : 3011)	NC score	0.377970 (rank : 961)
Query Neighborhood Hits	2923	Target Neighborhood Hits	624	Shared Neighborhood Hits	547
SwissProt Accessions	P25092	Gene names	GUCY2C, GUC2C, STAR
Domain Architecture
Description	Heat-stable enterotoxin receptor precursor (GC-C) (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) (hSTAR).

GUC2D_HUMAN
θ value	θ > 10 (rank : 3012)	NC score	0.374296 (rank : 963)
Query Neighborhood Hits	2923	Target Neighborhood Hits	715	Shared Neighborhood Hits	624
SwissProt Accessions	Q02846, Q6LEA7	Gene names	GUCY2D, CORD6, GUC1A4, GUC2D, RETGC, RETGC1
Domain Architecture
Description	Retinal guanylyl cyclase 1 precursor (EC 4.6.1.2) (Guanylate cyclase 2D, retinal) (RETGC-1) (Rod outer segment membrane guanylate cyclase) (ROS-GC).

GUC2E_MOUSE
θ value	θ > 10 (rank : 3013)	NC score	0.358840 (rank : 971)
Query Neighborhood Hits	2923	Target Neighborhood Hits	692	Shared Neighborhood Hits	600
SwissProt Accessions	P52785	Gene names	Gucy2e, Guc2e
Domain Architecture
Description	Guanylyl cyclase GC-E precursor (EC 4.6.1.2) (Guanylate cyclase 2E).

GUC2F_HUMAN
θ value	θ > 10 (rank : 3014)	NC score	0.417399 (rank : 923)
Query Neighborhood Hits	2923	Target Neighborhood Hits	740	Shared Neighborhood Hits	648
SwissProt Accessions	P51841, Q9UJF1	Gene names	GUCY2F, GUC2F, RETGC2
Domain Architecture
Description	Retinal guanylyl cyclase 2 precursor (EC 4.6.1.2) (Guanylate cyclase 2F, retinal) (RETGC-2) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2) (Guanylate cyclase F) (GC-F).

GUC2G_MOUSE
θ value	θ > 10 (rank : 3015)	NC score	0.350330 (rank : 976)
Query Neighborhood Hits	2923	Target Neighborhood Hits	644	Shared Neighborhood Hits	540
SwissProt Accessions	Q6TL19, Q8BWU7	Gene names	Gucy2g
Domain Architecture	No domain graphic available
Description	Guanylate cyclase 2G precursor (EC 4.6.1.2) (Guanylyl cyclase receptor G) (mGC-G).

HAPIP_HUMAN
θ value	θ > 10 (rank : 3016)	NC score	0.051923 (rank : 1663)
Query Neighborhood Hits	2923	Target Neighborhood Hits	350	Shared Neighborhood Hits	148
SwissProt Accessions	O60229	Gene names	HAPIP, DUO
Domain Architecture
Description	Huntingtin-associated protein-interacting protein (Protein Duo).

HIP1R_MOUSE
θ value	θ > 10 (rank : 3017)	NC score	0.053961 (rank : 1617)
Query Neighborhood Hits	2923	Target Neighborhood Hits	959	Shared Neighborhood Hits	392
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

ICAM1_HUMAN
θ value	θ > 10 (rank : 3018)	NC score	0.114127 (rank : 1176)
Query Neighborhood Hits	2923	Target Neighborhood Hits	80	Shared Neighborhood Hits	75
SwissProt Accessions	P05362, Q96B50	Gene names	ICAM1
Domain Architecture
Description	Intercellular adhesion molecule 1 precursor (ICAM-1) (Major group rhinovirus receptor) (CD54 antigen).

ICOSL_HUMAN
θ value	θ > 10 (rank : 3019)	NC score	0.060187 (rank : 1436)
Query Neighborhood Hits	2923	Target Neighborhood Hits	70	Shared Neighborhood Hits	63
SwissProt Accessions	O75144, Q9HD18, Q9NRQ1	Gene names	ICOSLG, B7H2, B7RP1, ICOSL, KIAA0653
Domain Architecture
Description	ICOS ligand precursor (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (CD275 antigen).

IFT74_MOUSE
θ value	θ > 10 (rank : 3020)	NC score	0.051297 (rank : 1676)
Query Neighborhood Hits	2923	Target Neighborhood Hits	939	Shared Neighborhood Hits	362
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

IFT81_HUMAN
θ value	θ > 10 (rank : 3021)	NC score	0.059147 (rank : 1465)
Query Neighborhood Hits	2923	Target Neighborhood Hits	893	Shared Neighborhood Hits	383
SwissProt Accessions	Q8WYA0, Q8NB51, Q9BSV2, Q9UNY8	Gene names	IFT81, CDV1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

IGSF8_HUMAN
θ value	θ > 10 (rank : 3022)	NC score	0.061450 (rank : 1403)
Query Neighborhood Hits	2923	Target Neighborhood Hits	88	Shared Neighborhood Hits	52
SwissProt Accessions	Q969P0, Q8NG09, Q96DP4, Q9BTG9	Gene names	IGSF8, CD81P3, EWI2, KCT4
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 8 precursor (CD81 partner 3) (Glu- Trp-Ile EWI motif-containing protein 2) (EWI-2) (Keratinocytes- associated transmembrane protein 4) (KCT-4) (LIR-D1) (CD316 antigen).

IGSF8_MOUSE
θ value	θ > 10 (rank : 3023)	NC score	0.055901 (rank : 1560)
Query Neighborhood Hits	2923	Target Neighborhood Hits	94	Shared Neighborhood Hits	59
SwissProt Accessions	Q8R366, Q8R0L7	Gene names	Igsf8, Ewi2, Kct4, Pgrl
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 8 precursor (CD81 partner 3) (Glu- Trp-Ile EWI motif-containing protein 2) (EWI-2) (Keratinocytes- associated transmembrane protein 4) (KCT-4) (Prostaglandin regulatory- like protein) (CD316 antigen).

IL18R_HUMAN
θ value	θ > 10 (rank : 3024)	NC score	0.056264 (rank : 1548)
Query Neighborhood Hits	2923	Target Neighborhood Hits	81	Shared Neighborhood Hits	48
SwissProt Accessions	Q13478	Gene names	IL18R1, IL1RRP
Domain Architecture
Description	Interleukin-18 receptor 1 precursor (IL1 receptor-related protein) (IL-1Rrp) (CDw218a antigen).

IL6RA_MOUSE
θ value	θ > 10 (rank : 3025)	NC score	0.088835 (rank : 1237)
Query Neighborhood Hits	2923	Target Neighborhood Hits	104	Shared Neighborhood Hits	97
SwissProt Accessions	P22272	Gene names	Il6ra, Il6r
Domain Architecture
Description	Interleukin-6 receptor alpha chain precursor (IL-6R-alpha) (IL-6R 1) (CD126 antigen).

INVO_HUMAN
θ value	θ > 10 (rank : 3026)	NC score	0.072311 (rank : 1295)
Query Neighborhood Hits	2923	Target Neighborhood Hits	636	Shared Neighborhood Hits	311
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

INVO_MOUSE
θ value	θ > 10 (rank : 3027)	NC score	0.068949 (rank : 1313)
Query Neighborhood Hits	2923	Target Neighborhood Hits	474	Shared Neighborhood Hits	260
SwissProt Accessions	P48997	Gene names	Ivl
Domain Architecture	No domain graphic available
Description	Involucrin.

IRAK1_HUMAN
θ value	θ > 10 (rank : 3028)	NC score	0.559047 (rank : 726)
Query Neighborhood Hits	2923	Target Neighborhood Hits	820	Shared Neighborhood Hits	728
SwissProt Accessions	P51617, Q7Z5V4, Q96RL2	Gene names	IRAK1, IRAK
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1).

IRAK1_MOUSE
θ value	θ > 10 (rank : 3029)	NC score	0.555120 (rank : 741)
Query Neighborhood Hits	2923	Target Neighborhood Hits	784	Shared Neighborhood Hits	710
SwissProt Accessions	Q62406, Q6Y3Z5, Q6Y3Z6	Gene names	Irak1, Il1rak
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK).

ITSN1_HUMAN
θ value	θ > 10 (rank : 3030)	NC score	0.059568 (rank : 1456)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1757	Shared Neighborhood Hits	598
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

ITSN2_HUMAN
θ value	θ > 10 (rank : 3031)	NC score	0.054269 (rank : 1602)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1173	Shared Neighborhood Hits	422
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

ITSN2_MOUSE
θ value	θ > 10 (rank : 3032)	NC score	0.056015 (rank : 1556)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1371	Shared Neighborhood Hits	486
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

KMHN1_HUMAN
θ value	θ > 10 (rank : 3033)	NC score	0.053033 (rank : 1637)
Query Neighborhood Hits	2923	Target Neighborhood Hits	950	Shared Neighborhood Hits	368
SwissProt Accessions	Q8TBZ0, Q86YI9, Q8N7W0	Gene names	KMHN1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1.

KMHN1_MOUSE
θ value	θ > 10 (rank : 3034)	NC score	0.054095 (rank : 1611)
Query Neighborhood Hits	2923	Target Neighborhood Hits	949	Shared Neighborhood Hits	383
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

LIPA1_HUMAN
θ value	θ > 10 (rank : 3035)	NC score	0.054213 (rank : 1604)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1294	Shared Neighborhood Hits	472
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

LUZP1_MOUSE
θ value	θ > 10 (rank : 3036)	NC score	0.054470 (rank : 1589)
Query Neighborhood Hits	2923	Target Neighborhood Hits	940	Shared Neighborhood Hits	399
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

MADCA_HUMAN
θ value	θ > 10 (rank : 3037)	NC score	0.073229 (rank : 1289)
Query Neighborhood Hits	2923	Target Neighborhood Hits	221	Shared Neighborhood Hits	132
SwissProt Accessions	Q13477, O60222, O75867	Gene names	MADCAM1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (hMAdCAM-1).

MARCS_HUMAN
θ value	θ > 10 (rank : 3038)	NC score	0.054338 (rank : 1596)
Query Neighborhood Hits	2923	Target Neighborhood Hits	204	Shared Neighborhood Hits	101
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

MARCS_MOUSE
θ value	θ > 10 (rank : 3039)	NC score	0.052223 (rank : 1658)
Query Neighborhood Hits	2923	Target Neighborhood Hits	227	Shared Neighborhood Hits	112
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

MBD6_HUMAN
θ value	θ > 10 (rank : 3040)	NC score	0.051599 (rank : 1669)
Query Neighborhood Hits	2923	Target Neighborhood Hits	349	Shared Neighborhood Hits	156
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

MD1L1_HUMAN
θ value	θ > 10 (rank : 3041)	NC score	0.056045 (rank : 1555)
Query Neighborhood Hits	2923	Target Neighborhood Hits	893	Shared Neighborhood Hits	360
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

MD1L1_MOUSE
θ value	θ > 10 (rank : 3042)	NC score	0.057888 (rank : 1495)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1001	Shared Neighborhood Hits	384
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

MET_HUMAN
θ value	θ > 10 (rank : 3043)	NC score	0.544411 (rank : 769)
Query Neighborhood Hits	2923	Target Neighborhood Hits	831	Shared Neighborhood Hits	750
SwissProt Accessions	P08581, O60366, Q12875, Q9UDX7, Q9UPL8	Gene names	MET
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

MET_MOUSE
θ value	θ > 10 (rank : 3044)	NC score	0.546574 (rank : 765)
Query Neighborhood Hits	2923	Target Neighborhood Hits	844	Shared Neighborhood Hits	755
SwissProt Accessions	P16056, Q62125	Gene names	Met
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

MLKL_HUMAN
θ value	θ > 10 (rank : 3045)	NC score	0.432874 (rank : 905)
Query Neighborhood Hits	2923	Target Neighborhood Hits	600	Shared Neighborhood Hits	544
SwissProt Accessions	Q8NB16, Q8N6V0	Gene names	MLKL
Domain Architecture	No domain graphic available
Description	Mixed lineage kinase domain-like protein.

MLKL_MOUSE
θ value	θ > 10 (rank : 3046)	NC score	0.511839 (rank : 832)
Query Neighborhood Hits	2923	Target Neighborhood Hits	707	Shared Neighborhood Hits	649
SwissProt Accessions	Q9D2Y4, Q8CIJ5	Gene names	Mlkl
Domain Architecture	No domain graphic available
Description	Mixed lineage kinase domain-like protein.

MUC7_HUMAN
θ value	θ > 10 (rank : 3047)	NC score	0.077637 (rank : 1271)
Query Neighborhood Hits	2923	Target Neighborhood Hits	538	Shared Neighborhood Hits	265
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

MY18B_HUMAN
θ value	θ > 10 (rank : 3048)	NC score	0.058661 (rank : 1478)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1299	Shared Neighborhood Hits	485
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

NAF1_HUMAN
θ value	θ > 10 (rank : 3049)	NC score	0.050359 (rank : 1699)
Query Neighborhood Hits	2923	Target Neighborhood Hits	937	Shared Neighborhood Hits	396
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

NAF1_MOUSE
θ value	θ > 10 (rank : 3050)	NC score	0.050152 (rank : 1701)
Query Neighborhood Hits	2923	Target Neighborhood Hits	852	Shared Neighborhood Hits	380
SwissProt Accessions	Q9WUU8, Q922A9, Q922F7, Q9EPP8, Q9R0X3	Gene names	Tnip1, Abin, Naf1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (A20- binding inhibitor of NF-kappa-B activation) (ABIN) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).

NCK1_HUMAN
θ value	θ > 10 (rank : 3051)	NC score	0.051514 (rank : 1671)
Query Neighborhood Hits	2923	Target Neighborhood Hits	312	Shared Neighborhood Hits	83
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

NCK2_HUMAN
θ value	θ > 10 (rank : 3052)	NC score	0.050381 (rank : 1698)
Query Neighborhood Hits	2923	Target Neighborhood Hits	310	Shared Neighborhood Hits	81
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

NEMO_HUMAN
θ value	θ > 10 (rank : 3053)	NC score	0.058296 (rank : 1484)
Query Neighborhood Hits	2923	Target Neighborhood Hits	820	Shared Neighborhood Hits	354
SwissProt Accessions	Q9Y6K9	Gene names	IKBKG, FIP3, NEMO
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (FIP-3).

NEMO_MOUSE
θ value	θ > 10 (rank : 3054)	NC score	0.051086 (rank : 1681)
Query Neighborhood Hits	2923	Target Neighborhood Hits	658	Shared Neighborhood Hits	293
SwissProt Accessions	O88522	Gene names	Ikbkg, Nemo
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (mFIP-3).

OFD1_HUMAN
θ value	θ > 10 (rank : 3055)	NC score	0.055697 (rank : 1563)
Query Neighborhood Hits	2923	Target Neighborhood Hits	753	Shared Neighborhood Hits	341
SwissProt Accessions	O75665, O75666	Gene names	OFD1, CXorf5
Domain Architecture	No domain graphic available
Description	Oral-facial-digital syndrome 1 protein (Protein 71-7A).

OX2G_HUMAN
θ value	θ > 10 (rank : 3056)	NC score	0.123576 (rank : 1164)
Query Neighborhood Hits	2923	Target Neighborhood Hits	100	Shared Neighborhood Hits	95
SwissProt Accessions	P41217, Q6J2Q6, Q6PIQ4, Q8TB85, Q9H3J3	Gene names	CD200, MOX2
Domain Architecture
Description	OX-2 membrane glycoprotein precursor (CD200 antigen).

P85B_MOUSE
θ value	θ > 10 (rank : 3057)	NC score	0.054062 (rank : 1612)
Query Neighborhood Hits	2923	Target Neighborhood Hits	519	Shared Neighborhood Hits	246
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

PACE1_HUMAN
θ value	θ > 10 (rank : 3058)	NC score	0.054414 (rank : 1593)
Query Neighborhood Hits	2923	Target Neighborhood Hits	74	Shared Neighborhood Hits	52
SwissProt Accessions	Q8IZE3, Q5THA6, Q5THA8, Q8IZN9, Q96C56, Q9UBK6	Gene names	SCYL3, PACE1
Domain Architecture	No domain graphic available
Description	Protein-associating with the carboxyl-terminal domain of ezrin (Ezrin- binding protein PACE-1) (SCY1-like protein 3).

PACE1_MOUSE
θ value	θ > 10 (rank : 3059)	NC score	0.056916 (rank : 1533)
Query Neighborhood Hits	2923	Target Neighborhood Hits	92	Shared Neighborhood Hits	65
SwissProt Accessions	Q9DBQ7, Q6NY01, Q8BQC9, Q8BRJ1	Gene names	Scyl3, Pace1
Domain Architecture	No domain graphic available
Description	Protein-associating with the carboxyl-terminal domain of ezrin (Ezrin- binding protein PACE-1) (SCY1-like protein 3).

PCQAP_HUMAN
θ value	θ > 10 (rank : 3060)	NC score	0.056793 (rank : 1539)
Query Neighborhood Hits	2923	Target Neighborhood Hits	549	Shared Neighborhood Hits	288
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

PDZD8_HUMAN
θ value	θ > 10 (rank : 3061)	NC score	0.070627 (rank : 1306)
Query Neighborhood Hits	2923	Target Neighborhood Hits	185	Shared Neighborhood Hits	86
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

PEPL_HUMAN
θ value	θ > 10 (rank : 3062)	NC score	0.057283 (rank : 1515)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1141	Shared Neighborhood Hits	426
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

PININ_HUMAN
θ value	θ > 10 (rank : 3063)	NC score	0.071367 (rank : 1300)
Query Neighborhood Hits	2923	Target Neighborhood Hits	753	Shared Neighborhood Hits	382
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

PININ_MOUSE
θ value	θ > 10 (rank : 3064)	NC score	0.066049 (rank : 1334)
Query Neighborhood Hits	2923	Target Neighborhood Hits	777	Shared Neighborhood Hits	398
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

PINK1_HUMAN
θ value	θ > 10 (rank : 3065)	NC score	0.608318 (rank : 619)
Query Neighborhood Hits	2923	Target Neighborhood Hits	741	Shared Neighborhood Hits	691
SwissProt Accessions	Q9BXM7, Q8N6T9, Q8NBU3, Q96DE4	Gene names	PINK1
Domain Architecture
Description	Serine/threonine-protein kinase PINK1, mitochondrial precursor (EC 2.7.11.1) (PTEN-induced putative kinase protein 1) (BRPK).

PRB3_HUMAN
θ value	θ > 10 (rank : 3066)	NC score	0.057895 (rank : 1494)
Query Neighborhood Hits	2923	Target Neighborhood Hits	318	Shared Neighborhood Hits	149
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

PRP2_MOUSE
θ value	θ > 10 (rank : 3067)	NC score	0.071262 (rank : 1301)
Query Neighborhood Hits	2923	Target Neighborhood Hits	347	Shared Neighborhood Hits	164
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PRPK_HUMAN
θ value	θ > 10 (rank : 3068)	NC score	0.120039 (rank : 1170)
Query Neighborhood Hits	2923	Target Neighborhood Hits	131	Shared Neighborhood Hits	123
SwissProt Accessions	Q96S44, Q3T977, Q5JZ01, Q96FM7, Q9NQE6	Gene names	TP53RK, C20orf64, PRPK
Domain Architecture
Description	TP53-regulating kinase (EC 2.7.11.1) (p53-related protein kinase) (Nori-2).

PRPK_MOUSE
θ value	θ > 10 (rank : 3069)	NC score	0.117758 (rank : 1173)
Query Neighborhood Hits	2923	Target Neighborhood Hits	139	Shared Neighborhood Hits	129
SwissProt Accessions	Q99PW4, Q91W37, Q9CZ32	Gene names	Tp53rk, Prpk, Trp53rk
Domain Architecture
Description	TP53-regulating kinase (EC 2.7.11.1) (p53-related protein kinase) (Nori-2).

PRR12_HUMAN
θ value	θ > 10 (rank : 3070)	NC score	0.069573 (rank : 1311)
Query Neighborhood Hits	2923	Target Neighborhood Hits	460	Shared Neighborhood Hits	224
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

PTN11_HUMAN
θ value	θ > 10 (rank : 3071)	NC score	0.061002 (rank : 1414)
Query Neighborhood Hits	2923	Target Neighborhood Hits	227	Shared Neighborhood Hits	85
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTN11_MOUSE
θ value	θ > 10 (rank : 3072)	NC score	0.060930 (rank : 1417)
Query Neighborhood Hits	2923	Target Neighborhood Hits	227	Shared Neighborhood Hits	85
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

PTN23_HUMAN
θ value	θ > 10 (rank : 3073)	NC score	0.054331 (rank : 1598)
Query Neighborhood Hits	2923	Target Neighborhood Hits	646	Shared Neighborhood Hits	303
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

PTN6_HUMAN
θ value	θ > 10 (rank : 3074)	NC score	0.055369 (rank : 1568)
Query Neighborhood Hits	2923	Target Neighborhood Hits	234	Shared Neighborhood Hits	87
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

PTN6_MOUSE
θ value	θ > 10 (rank : 3075)	NC score	0.056298 (rank : 1547)
Query Neighborhood Hits	2923	Target Neighborhood Hits	225	Shared Neighborhood Hits	81
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

PTPRZ_HUMAN
θ value	θ > 10 (rank : 3076)	NC score	0.051152 (rank : 1679)
Query Neighborhood Hits	2923	Target Neighborhood Hits	255	Shared Neighborhood Hits	91
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

PXK_HUMAN
θ value	θ > 10 (rank : 3077)	NC score	0.105412 (rank : 1196)
Query Neighborhood Hits	2923	Target Neighborhood Hits	216	Shared Neighborhood Hits	151
SwissProt Accessions	Q7Z7A4, Q3BCH4, Q3BCH5, Q3BCH6, Q3BDW1, Q45L83, Q59EX3, Q6PK17, Q6ZN39, Q96CA3, Q96R07, Q9NXB8	Gene names	PXK
Domain Architecture	No domain graphic available
Description	PX domain-containing protein kinase-like protein (Modulator of Na,K- ATPase) (MONaKA).

PXK_MOUSE
θ value	θ > 10 (rank : 3078)	NC score	0.145253 (rank : 1142)
Query Neighborhood Hits	2923	Target Neighborhood Hits	320	Shared Neighborhood Hits	229
SwissProt Accessions	Q8BX57, Q3TD60, Q3TEL7, Q3TZZ1, Q3U197, Q3U773, Q3UCS5, Q4FBH7, Q91WB6	Gene names	Pxk
Domain Architecture	No domain graphic available
Description	PX domain-containing protein kinase-like protein (Modulator of Na,K- ATPase) (MONaKA).

RASF1_HUMAN
θ value	θ > 10 (rank : 3079)	NC score	0.053885 (rank : 1619)
Query Neighborhood Hits	2923	Target Neighborhood Hits	62	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NS23, O14571, O60539, O60710, Q9HB04, Q9HB18, Q9NS22, Q9UND4, Q9UND5	Gene names	RASSF1, RDA32
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 1.

RASF1_MOUSE
θ value	θ > 10 (rank : 3080)	NC score	0.065741 (rank : 1340)
Query Neighborhood Hits	2923	Target Neighborhood Hits	74	Shared Neighborhood Hits	37
SwissProt Accessions	Q99MK9, Q9WUF5	Gene names	Rassf1
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 1 (Protein 123F2).

RBCC1_MOUSE
θ value	θ > 10 (rank : 3081)	NC score	0.057367 (rank : 1511)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1048	Shared Neighborhood Hits	404
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

RBM25_HUMAN
θ value	θ > 10 (rank : 3082)	NC score	0.064254 (rank : 1353)
Query Neighborhood Hits	2923	Target Neighborhood Hits	682	Shared Neighborhood Hits	327
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

REN3B_HUMAN
θ value	θ > 10 (rank : 3083)	NC score	0.050626 (rank : 1688)
Query Neighborhood Hits	2923	Target Neighborhood Hits	412	Shared Neighborhood Hits	220
SwissProt Accessions	Q9BZI7, Q9H1J0	Gene names	UPF3B, RENT3B, UPF3X
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3B (Nonsense mRNA reducing factor 3B) (Up-frameshift suppressor 3 homolog B) (hUpf3B) (hUpf3p-X).

RFIP3_HUMAN
θ value	θ > 10 (rank : 3084)	NC score	0.051748 (rank : 1667)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1055	Shared Neighborhood Hits	415
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

RIPK2_HUMAN
θ value	θ > 10 (rank : 3085)	NC score	0.573143 (rank : 700)
Query Neighborhood Hits	2923	Target Neighborhood Hits	774	Shared Neighborhood Hits	708
SwissProt Accessions	O43353, Q6UWF0	Gene names	RIPK2, CARDIAK, RICK, RIP2
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (CARD-containing interleukin-1 beta-converting enzyme- associated kinase) (CARD-containing IL-1 beta ICE-kinase).

RIPK4_HUMAN
θ value	θ > 10 (rank : 3086)	NC score	0.477783 (rank : 878)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1094	Shared Neighborhood Hits	776
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

RN5A_HUMAN
θ value	θ > 10 (rank : 3087)	NC score	0.114221 (rank : 1175)
Query Neighborhood Hits	2923	Target Neighborhood Hits	608	Shared Neighborhood Hits	353
SwissProt Accessions	Q05823	Gene names	RNASEL, RNS4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

RON_HUMAN
θ value	θ > 10 (rank : 3088)	NC score	0.549383 (rank : 760)
Query Neighborhood Hits	2923	Target Neighborhood Hits	842	Shared Neighborhood Hits	759
SwissProt Accessions	Q04912	Gene names	MST1R, RON
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (CDw136 antigen) [Contains: Macrophage- stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

RON_MOUSE
θ value	θ > 10 (rank : 3089)	NC score	0.541793 (rank : 771)
Query Neighborhood Hits	2923	Target Neighborhood Hits	836	Shared Neighborhood Hits	755
SwissProt Accessions	Q62190, Q62555	Gene names	Mst1r, Ron, Stk
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

SDCG8_HUMAN
θ value	θ > 10 (rank : 3090)	NC score	0.062968 (rank : 1376)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1002	Shared Neighborhood Hits	406
SwissProt Accessions	Q86SQ7, O60527, Q3ZCR6, Q8N5F2, Q9P0F1	Gene names	SDCCAG8, CCCAP
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (hCCCAP) (Antigen NY-CO-8).

SDCG8_MOUSE
θ value	θ > 10 (rank : 3091)	NC score	0.060318 (rank : 1433)
Query Neighborhood Hits	2923	Target Neighborhood Hits	886	Shared Neighborhood Hits	376
SwissProt Accessions	Q80UF4	Gene names	Sdccag8, Cccap
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (mCCCAP).

SH21B_MOUSE
θ value	θ > 10 (rank : 3092)	NC score	0.052614 (rank : 1645)
Query Neighborhood Hits	2923	Target Neighborhood Hits	101	Shared Neighborhood Hits	44
SwissProt Accessions	O35324, Q8C268	Gene names	Sh2d1b, Eat2, Sh2d1b1
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

SH24A_HUMAN
θ value	θ > 10 (rank : 3093)	NC score	0.055636 (rank : 1565)
Query Neighborhood Hits	2923	Target Neighborhood Hits	455	Shared Neighborhood Hits	241
SwissProt Accessions	Q9H788, Q5XKC1, Q6NXE9, Q86YM2, Q96C88, Q9H7F7	Gene names	SH2D4A, SH2A
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 4A (Protein SH(2)A).

SLAP1_HUMAN
θ value	θ > 10 (rank : 3094)	NC score	0.075020 (rank : 1280)
Query Neighborhood Hits	2923	Target Neighborhood Hits	113	Shared Neighborhood Hits	43
SwissProt Accessions	Q13239, Q9UMQ8	Gene names	SLA, SLAP, SLAP1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (hSLAP).

SLAP1_MOUSE
θ value	θ > 10 (rank : 3095)	NC score	0.073989 (rank : 1286)
Query Neighborhood Hits	2923	Target Neighborhood Hits	117	Shared Neighborhood Hits	46
SwissProt Accessions	Q60898, Q8C9Q8, Q8CAT0, Q8CBE9, Q8QZX8	Gene names	Sla, Slap, Slap1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (mSLAP).

SLAP2_HUMAN
θ value	θ > 10 (rank : 3096)	NC score	0.076195 (rank : 1276)
Query Neighborhood Hits	2923	Target Neighborhood Hits	139	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H6Q3, Q5TH27, Q5TH28, Q8WY18, Q96QI4, Q9H135	Gene names	SLA2, C20orf156, SLAP2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2) (Modulator of antigen receptor signaling) (MARS).

SLAP2_MOUSE
θ value	θ > 10 (rank : 3097)	NC score	0.078842 (rank : 1268)
Query Neighborhood Hits	2923	Target Neighborhood Hits	136	Shared Neighborhood Hits	47
SwissProt Accessions	Q8R4L0, Q3UU74, Q8C0K2, Q8VI42, Q9D1Z9	Gene names	Sla2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2).

SM1L2_HUMAN
θ value	θ > 10 (rank : 3098)	NC score	0.053161 (rank : 1633)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1019	Shared Neighborhood Hits	407
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

SMC1A_HUMAN
θ value	θ > 10 (rank : 3099)	NC score	0.054318 (rank : 1599)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1346	Shared Neighborhood Hits	483
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

SMC1A_MOUSE
θ value	θ > 10 (rank : 3100)	NC score	0.057053 (rank : 1526)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1384	Shared Neighborhood Hits	497
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

STAC3_HUMAN
θ value	θ > 10 (rank : 3101)	NC score	0.068099 (rank : 1321)
Query Neighborhood Hits	2923	Target Neighborhood Hits	228	Shared Neighborhood Hits	83
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC3_MOUSE
θ value	θ > 10 (rank : 3102)	NC score	0.068895 (rank : 1314)
Query Neighborhood Hits	2923	Target Neighborhood Hits	232	Shared Neighborhood Hits	81
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC_HUMAN
θ value	θ > 10 (rank : 3103)	NC score	0.065889 (rank : 1338)
Query Neighborhood Hits	2923	Target Neighborhood Hits	276	Shared Neighborhood Hits	102
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

STAC_MOUSE
θ value	θ > 10 (rank : 3104)	NC score	0.070602 (rank : 1307)
Query Neighborhood Hits	2923	Target Neighborhood Hits	268	Shared Neighborhood Hits	102
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

STK31_HUMAN
θ value	θ > 10 (rank : 3105)	NC score	0.294817 (rank : 1007)
Query Neighborhood Hits	2923	Target Neighborhood Hits	570	Shared Neighborhood Hits	476
SwissProt Accessions	Q9BXU1, Q9BXH8	Gene names	STK31
Domain Architecture
Description	Serine/threonine-protein kinase 31 (EC 2.7.11.1) (Serine/threonine- protein kinase NYD-SPK).

STK31_MOUSE
θ value	θ > 10 (rank : 3106)	NC score	0.252658 (rank : 1030)
Query Neighborhood Hits	2923	Target Neighborhood Hits	474	Shared Neighborhood Hits	409
SwissProt Accessions	Q99MW1	Gene names	Stk31
Domain Architecture
Description	Serine/threonine-protein kinase 31 (EC 2.7.11.1).

SWP70_HUMAN
θ value	θ > 10 (rank : 3107)	NC score	0.057302 (rank : 1514)
Query Neighborhood Hits	2923	Target Neighborhood Hits	973	Shared Neighborhood Hits	381
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SWP70_MOUSE
θ value	θ > 10 (rank : 3108)	NC score	0.059958 (rank : 1443)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1097	Shared Neighborhood Hits	421
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

TAF4_HUMAN
θ value	θ > 10 (rank : 3109)	NC score	0.060495 (rank : 1428)
Query Neighborhood Hits	2923	Target Neighborhood Hits	687	Shared Neighborhood Hits	313
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

TARA_MOUSE
θ value	θ > 10 (rank : 3110)	NC score	0.057254 (rank : 1517)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1133	Shared Neighborhood Hits	469
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TCOF_MOUSE
θ value	θ > 10 (rank : 3111)	NC score	0.067650 (rank : 1326)
Query Neighborhood Hits	2923	Target Neighborhood Hits	471	Shared Neighborhood Hits	225
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

TEX14_MOUSE
θ value	θ > 10 (rank : 3112)	NC score	0.408701 (rank : 940)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1333	Shared Neighborhood Hits	828
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

TGFR1_HUMAN
θ value	θ > 10 (rank : 3113)	NC score	0.483503 (rank : 865)
Query Neighborhood Hits	2923	Target Neighborhood Hits	755	Shared Neighborhood Hits	704
SwissProt Accessions	P36897	Gene names	TGFBR1
Domain Architecture
Description	TGF-beta receptor type-1 precursor (EC 2.7.11.30) (TGF-beta receptor type I) (TGFR-1) (TGF-beta type I receptor) (Serine/threonine-protein kinase receptor R4) (SKR4) (Activin receptor-like kinase 5) (ALK-5).

TGFR1_MOUSE
θ value	θ > 10 (rank : 3114)	NC score	0.483282 (rank : 866)
Query Neighborhood Hits	2923	Target Neighborhood Hits	753	Shared Neighborhood Hits	704
SwissProt Accessions	Q64729	Gene names	Tgfbr1
Domain Architecture
Description	TGF-beta receptor type-1 precursor (EC 2.7.11.30) (TGF-beta receptor type I) (TGFR-1) (TGF-beta type I receptor) (ESK2).

TGFR2_HUMAN
θ value	θ > 10 (rank : 3115)	NC score	0.508562 (rank : 836)
Query Neighborhood Hits	2923	Target Neighborhood Hits	748	Shared Neighborhood Hits	693
SwissProt Accessions	P37173, Q15580, Q6DKT6, Q99474	Gene names	TGFBR2
Domain Architecture
Description	TGF-beta receptor type-2 precursor (EC 2.7.11.30) (TGF-beta receptor type II) (TGFR-2) (TGF-beta type II receptor).

TIMD1_HUMAN
θ value	θ > 10 (rank : 3116)	NC score	0.053944 (rank : 1618)
Query Neighborhood Hits	2923	Target Neighborhood Hits	155	Shared Neighborhood Hits	101
SwissProt Accessions	Q96D42, O43656	Gene names	HAVCR1, TIM1, TIMD1
Domain Architecture	No domain graphic available
Description	Hepatitis A virus cellular receptor 1 precursor (HAVcr-1) (T cell immunoglobulin and mucin domain-containing protein 1) (TIMD-1) (T cell membrane protein 1) (TIM-1) (TIM).

TNI3K_HUMAN
θ value	θ > 10 (rank : 3117)	NC score	0.533880 (rank : 796)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1084	Shared Neighborhood Hits	769
SwissProt Accessions	Q59H18, Q49AR1, Q6MZS9, Q9Y2V6	Gene names	TNNI3K, CARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

TXLNB_HUMAN
θ value	θ > 10 (rank : 3118)	NC score	0.050302 (rank : 1700)
Query Neighborhood Hits	2923	Target Neighborhood Hits	912	Shared Neighborhood Hits	382
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

UN13B_HUMAN
θ value	θ > 10 (rank : 3119)	NC score	0.061981 (rank : 1393)
Query Neighborhood Hits	2923	Target Neighborhood Hits	217	Shared Neighborhood Hits	66
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

UN13B_MOUSE
θ value	θ > 10 (rank : 3120)	NC score	0.059718 (rank : 1452)
Query Neighborhood Hits	2923	Target Neighborhood Hits	210	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

VAV2_HUMAN
θ value	θ > 10 (rank : 3121)	NC score	0.056889 (rank : 1535)
Query Neighborhood Hits	2923	Target Neighborhood Hits	453	Shared Neighborhood Hits	136
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

VAV2_MOUSE
θ value	θ > 10 (rank : 3122)	NC score	0.055028 (rank : 1576)
Query Neighborhood Hits	2923	Target Neighborhood Hits	456	Shared Neighborhood Hits	135
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

VAV3_HUMAN
θ value	θ > 10 (rank : 3123)	NC score	0.059963 (rank : 1442)
Query Neighborhood Hits	2923	Target Neighborhood Hits	398	Shared Neighborhood Hits	118
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

VAV3_MOUSE
θ value	θ > 10 (rank : 3124)	NC score	0.059973 (rank : 1441)
Query Neighborhood Hits	2923	Target Neighborhood Hits	404	Shared Neighborhood Hits	127
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

VAV_HUMAN
θ value	θ > 10 (rank : 3125)	NC score	0.061570 (rank : 1399)
Query Neighborhood Hits	2923	Target Neighborhood Hits	452	Shared Neighborhood Hits	135
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

VAV_MOUSE
θ value	θ > 10 (rank : 3126)	NC score	0.056840 (rank : 1538)
Query Neighborhood Hits	2923	Target Neighborhood Hits	430	Shared Neighborhood Hits	129
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

WASIP_HUMAN
θ value	θ > 10 (rank : 3127)	NC score	0.062754 (rank : 1380)
Query Neighborhood Hits	2923	Target Neighborhood Hits	458	Shared Neighborhood Hits	229
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

WASIP_MOUSE
θ value	θ > 10 (rank : 3128)	NC score	0.052887 (rank : 1639)
Query Neighborhood Hits	2923	Target Neighborhood Hits	392	Shared Neighborhood Hits	198
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

WNK4_HUMAN
θ value	θ > 10 (rank : 3129)	NC score	0.653744 (rank : 541)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1043	Shared Neighborhood Hits	839
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

XE7_HUMAN
θ value	θ > 10 (rank : 3130)	NC score	0.060831 (rank : 1419)
Query Neighborhood Hits	2923	Target Neighborhood Hits	738	Shared Neighborhood Hits	338
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

YLPM1_MOUSE
θ value	θ > 10 (rank : 3131)	NC score	0.051352 (rank : 1675)
Query Neighborhood Hits	2923	Target Neighborhood Hits	505	Shared Neighborhood Hits	240
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

Hits sorted by NC score

TITIN_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	2923	Target Neighborhood Hits	2923	Shared Neighborhood Hits	2923
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

OBSCN_HUMAN
NC score	0.903999 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1931	Shared Neighborhood Hits	1346
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

MYLK_HUMAN
NC score	0.902152 (rank : 3)	θ value	2.62879e-100 (rank : 5)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1328	Shared Neighborhood Hits	1146
SwissProt Accessions	Q15746, O95796, O95797, O95798, O95799, Q14844, Q16794, Q5MY99, Q5MYA0, Q7Z4J0, Q9C0L5, Q9UBG5, Q9UIT9	Gene names	MYLK, MLCK
Domain Architecture
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

MYLK_MOUSE
NC score	0.901136 (rank : 4)	θ value	5.85632e-100 (rank : 6)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1489	Shared Neighborhood Hits	1223
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

SPEG_MOUSE
NC score	0.889508 (rank : 5)	θ value	2.18062e-54 (rank : 30)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1959	Shared Neighborhood Hits	1341
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SPEG_HUMAN
NC score	0.889460 (rank : 6)	θ value	7.75577e-52 (rank : 35)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1762	Shared Neighborhood Hits	1282
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

DUET_HUMAN
NC score	0.824743 (rank : 7)	θ value	2.03627e-60 (rank : 20)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1220	Shared Neighborhood Hits	1026
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

TRIO_HUMAN
NC score	0.776941 (rank : 8)	θ value	5.96599e-36 (rank : 81)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1580	Shared Neighborhood Hits	1212
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

DAPK2_HUMAN
NC score	0.761178 (rank : 9)	θ value	2.18062e-54 (rank : 29)
Query Neighborhood Hits	2923	Target Neighborhood Hits	832	Shared Neighborhood Hits	787
SwissProt Accessions	Q9UIK4, O75892	Gene names	DAPK2
Domain Architecture
Description	Death-associated protein kinase 2 (EC 2.7.11.1) (DAP kinase 2) (DAP- kinase-related protein 1) (DRP-1).

DAPK2_MOUSE
NC score	0.760354 (rank : 10)	θ value	6.34462e-54 (rank : 31)
Query Neighborhood Hits	2923	Target Neighborhood Hits	834	Shared Neighborhood Hits	789
SwissProt Accessions	Q8VDF3, O88861, Q9QYM4	Gene names	Dapk2
Domain Architecture
Description	Death-associated protein kinase 2 (EC 2.7.11.1) (DAP kinase 2) (DAP- kinase-related protein 1) (DRP-1).

ST17A_HUMAN
NC score	0.759891 (rank : 11)	θ value	2.1121e-49 (rank : 36)
Query Neighborhood Hits	2923	Target Neighborhood Hits	843	Shared Neighborhood Hits	790
SwissProt Accessions	Q9UEE5, Q8IVC8	Gene names	STK17A, DRAK1
Domain Architecture
Description	Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 1).

DAPK3_MOUSE
NC score	0.759809 (rank : 12)	θ value	5.73848e-55 (rank : 26)
Query Neighborhood Hits	2923	Target Neighborhood Hits	843	Shared Neighborhood Hits	792
SwissProt Accessions	O54784	Gene names	Dapk3, Zipk
Domain Architecture
Description	Death-associated protein kinase 3 (EC 2.7.11.1) (DAP kinase 3) (DAP- like kinase) (Dlk) (ZIP-kinase).

DAPK3_HUMAN
NC score	0.759705 (rank : 13)	θ value	7.49467e-55 (rank : 27)
Query Neighborhood Hits	2923	Target Neighborhood Hits	945	Shared Neighborhood Hits	848
SwissProt Accessions	O43293	Gene names	DAPK3, ZIPK
Domain Architecture
Description	Death-associated protein kinase 3 (EC 2.7.11.1) (DAP kinase 3) (DAP- like kinase) (Dlk) (ZIP-kinase).

MYLK2_HUMAN
NC score	0.759385 (rank : 14)	θ value	3.0428e-56 (rank : 23)
Query Neighborhood Hits	2923	Target Neighborhood Hits	920	Shared Neighborhood Hits	830
SwissProt Accessions	Q9H1R3, Q96I84	Gene names	MYLK2
Domain Architecture
Description	Myosin light chain kinase 2, skeletal/cardiac muscle (EC 2.7.11.18) (MLCK2).

ST17B_HUMAN
NC score	0.757065 (rank : 15)	θ value	6.35935e-46 (rank : 38)
Query Neighborhood Hits	2923	Target Neighborhood Hits	833	Shared Neighborhood Hits	784
SwissProt Accessions	O94768	Gene names	STK17B, DRAK2
Domain Architecture
Description	Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 2).

ST17B_MOUSE
NC score	0.756993 (rank : 16)	θ value	1.08474e-45 (rank : 39)
Query Neighborhood Hits	2923	Target Neighborhood Hits	838	Shared Neighborhood Hits	788
SwissProt Accessions	Q8BG48, Q3TNG7, Q8BLV9, Q923E7	Gene names	Stk17b, Drak2
Domain Architecture
Description	Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 2).

KPSH2_HUMAN
NC score	0.754003 (rank : 17)	θ value	1.20211e-36 (rank : 74)
Query Neighborhood Hits	2923	Target Neighborhood Hits	822	Shared Neighborhood Hits	783
SwissProt Accessions	Q96QS6	Gene names	PSKH2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase H2 (EC 2.7.11.1) (PSK-H2).

KCC1A_MOUSE
NC score	0.753507 (rank : 18)	θ value	3.73686e-38 (rank : 65)
Query Neighborhood Hits	2923	Target Neighborhood Hits	845	Shared Neighborhood Hits	793
SwissProt Accessions	Q91YS8	Gene names	Camk1
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha).

KCC1A_HUMAN
NC score	0.753359 (rank : 19)	θ value	1.08726e-37 (rank : 67)
Query Neighborhood Hits	2923	Target Neighborhood Hits	846	Shared Neighborhood Hits	793
SwissProt Accessions	Q14012	Gene names	CAMK1
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha).

KPSH1_HUMAN
NC score	0.752839 (rank : 20)	θ value	1.79215e-40 (rank : 54)
Query Neighborhood Hits	2923	Target Neighborhood Hits	842	Shared Neighborhood Hits	787
SwissProt Accessions	P11801, Q9NY19	Gene names	PSKH1
Domain Architecture
Description	Serine/threonine-protein kinase H1 (EC 2.7.11.1) (PSK-H1).

KCC4_MOUSE
NC score	0.752647 (rank : 21)	θ value	3.26607e-42 (rank : 46)
Query Neighborhood Hits	2923	Target Neighborhood Hits	899	Shared Neighborhood Hits	823
SwissProt Accessions	P08414, Q61381	Gene names	Camk4
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type IV (EC 2.7.11.17) (CAM kinase-GR) (CaMK IV).

KPSH1_MOUSE
NC score	0.752522 (rank : 22)	θ value	5.21438e-40 (rank : 57)
Query Neighborhood Hits	2923	Target Neighborhood Hits	839	Shared Neighborhood Hits	787
SwissProt Accessions	Q91YA2, Q3U3V3	Gene names	Pskh1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase H1 (EC 2.7.11.1) (PSK-H1).

KCC1B_MOUSE
NC score	0.752381 (rank : 23)	θ value	8.61488e-35 (rank : 87)
Query Neighborhood Hits	2923	Target Neighborhood Hits	842	Shared Neighborhood Hits	789
SwissProt Accessions	Q9QYK9, Q80W07	Gene names	Pnck
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase type 1B (EC 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase homolog).

KCC4_HUMAN
NC score	0.752377 (rank : 24)	θ value	3.26607e-42 (rank : 45)
Query Neighborhood Hits	2923	Target Neighborhood Hits	841	Shared Neighborhood Hits	784
SwissProt Accessions	Q16566	Gene names	CAMK4
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type IV (EC 2.7.11.17) (CAM kinase-GR) (CaMK IV).

KCC1B_HUMAN
NC score	0.752336 (rank : 25)	θ value	4.27553e-34 (rank : 99)
Query Neighborhood Hits	2923	Target Neighborhood Hits	842	Shared Neighborhood Hits	789
SwissProt Accessions	Q6P2M8	Gene names	PNCK
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase type 1B (EC 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase).

KCC1D_MOUSE
NC score	0.752329 (rank : 26)	θ value	2.19075e-38 (rank : 63)
Query Neighborhood Hits	2923	Target Neighborhood Hits	847	Shared Neighborhood Hits	789
SwissProt Accessions	Q8BW96, Q3U450, Q80W64, Q8BWI7	Gene names	Camk1d
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK) (mCKLiK).

KCC1D_HUMAN
NC score	0.752199 (rank : 27)	θ value	2.19075e-38 (rank : 62)
Query Neighborhood Hits	2923	Target Neighborhood Hits	846	Shared Neighborhood Hits	788
SwissProt Accessions	Q8IU85, Q9HD31	Gene names	CAMK1D
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK).

DCAK3_HUMAN
NC score	0.751028 (rank : 28)	θ value	6.59618e-35 (rank : 84)
Query Neighborhood Hits	2923	Target Neighborhood Hits	888	Shared Neighborhood Hits	812
SwissProt Accessions	Q9C098	Gene names	DCAMKL3, KIAA1765
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL3 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 3).

DCAK3_MOUSE
NC score	0.750606 (rank : 29)	θ value	7.29293e-34 (rank : 103)
Query Neighborhood Hits	2923	Target Neighborhood Hits	922	Shared Neighborhood Hits	818
SwissProt Accessions	Q8BWQ5, Q1A748	Gene names	Dcamkl3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL3 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 3) (CLICK-I and II-related) (CLr).

KCC1G_MOUSE
NC score	0.750473 (rank : 30)	θ value	4.27553e-34 (rank : 101)
Query Neighborhood Hits	2923	Target Neighborhood Hits	851	Shared Neighborhood Hits	790
SwissProt Accessions	Q91VB2	Gene names	Camk1g
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase type 1G (EC 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM- KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III).

KCC1G_HUMAN
NC score	0.750442 (rank : 31)	θ value	4.27553e-34 (rank : 100)
Query Neighborhood Hits	2923	Target Neighborhood Hits	850	Shared Neighborhood Hits	791
SwissProt Accessions	Q96NX5, Q86UH5, Q9Y3J7	Gene names	CAMK1G, VWS1
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase type 1G (EC 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM- KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III).

KCC2G_MOUSE
NC score	0.750330 (rank : 32)	θ value	3.16345e-37 (rank : 70)
Query Neighborhood Hits	2923	Target Neighborhood Hits	838	Shared Neighborhood Hits	788
SwissProt Accessions	Q923T9, Q3U3H3, Q8VED3	Gene names	Camk2g
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type II gamma chain (EC 2.7.11.17) (CaM-kinase II gamma chain) (CaM kinase II gamma subunit) (CaMK-II subunit gamma).

KCC2G_HUMAN
NC score	0.750306 (rank : 33)	θ value	3.16345e-37 (rank : 69)
Query Neighborhood Hits	2923	Target Neighborhood Hits	841	Shared Neighborhood Hits	787
SwissProt Accessions	Q13555, O15378, Q13556, Q5SQZ4	Gene names	CAMK2G
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase type II gamma chain (EC 2.7.11.17) (CaM-kinase II gamma chain) (CaM kinase II gamma subunit) (CaMK-II subunit gamma).

MAPK2_MOUSE
NC score	0.750177 (rank : 34)	θ value	1.57365e-28 (rank : 145)
Query Neighborhood Hits	2923	Target Neighborhood Hits	831	Shared Neighborhood Hits	783
SwissProt Accessions	P49138, Q6P561	Gene names	Mapkapk2, Rps6kc1
Domain Architecture	No domain graphic available
Description	MAP kinase-activated protein kinase 2 (EC 2.7.11.1) (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAPK-2) (MK2).

MAPK2_HUMAN
NC score	0.750018 (rank : 35)	θ value	2.96777e-27 (rank : 158)
Query Neighborhood Hits	2923	Target Neighborhood Hits	844	Shared Neighborhood Hits	786
SwissProt Accessions	P49137, Q8IYD6	Gene names	MAPKAPK2
Domain Architecture
Description	MAP kinase-activated protein kinase 2 (EC 2.7.11.1) (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAPK-2) (MK2).

KCC2A_HUMAN
NC score	0.749931 (rank : 36)	θ value	3.4976e-36 (rank : 77)
Query Neighborhood Hits	2923	Target Neighborhood Hits	830	Shared Neighborhood Hits	783
SwissProt Accessions	Q9UQM7, Q9Y352	Gene names	CAMK2A
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type II alpha chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II subunit alpha).

KCC2B_HUMAN
NC score	0.749799 (rank : 37)	θ value	1.12514e-34 (rank : 89)
Query Neighborhood Hits	2923	Target Neighborhood Hits	866	Shared Neighborhood Hits	800
SwissProt Accessions	Q13554, O95437, O95438, O95599, Q9UGH7, Q9UGH8, Q9UGH9, Q9UNX0, Q9UNX7, Q9UP00, Q9Y5N4, Q9Y6F4	Gene names	CAMK2B, CAM2, CAMKB
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type II beta chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II subunit beta) (CaMK-II subunit beta).

KCC2A_MOUSE
NC score	0.749711 (rank : 38)	θ value	4.568e-36 (rank : 79)
Query Neighborhood Hits	2923	Target Neighborhood Hits	829	Shared Neighborhood Hits	783
SwissProt Accessions	P11798, Q61284	Gene names	Camk2a
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type II alpha chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II subunit alpha).

KCC2D_HUMAN
NC score	0.749563 (rank : 39)	θ value	7.04741e-37 (rank : 71)
Query Neighborhood Hits	2923	Target Neighborhood Hits	830	Shared Neighborhood Hits	786
SwissProt Accessions	Q13557, Q9UGH6, Q9UQE9	Gene names	CAMK2D
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type II delta chain (EC 2.7.11.17) (CaM-kinase II delta chain) (CaM kinase II subunit delta) (CaMK-II subunit delta).

MAPK3_MOUSE
NC score	0.747900 (rank : 40)	θ value	1.92365e-26 (rank : 161)
Query Neighborhood Hits	2923	Target Neighborhood Hits	811	Shared Neighborhood Hits	770
SwissProt Accessions	Q3UMW7, Q3T9E6, Q8K0G3	Gene names	Mapkapk3
Domain Architecture	No domain graphic available
Description	MAP kinase-activated protein kinase 3 (EC 2.7.11.1) (MAPK-activated protein kinase 3) (MAPKAP kinase 3) (MAPKAPK-3).

KCC2B_MOUSE
NC score	0.747648 (rank : 41)	θ value	1.12514e-34 (rank : 90)
Query Neighborhood Hits	2923	Target Neighborhood Hits	841	Shared Neighborhood Hits	783
SwissProt Accessions	P28652, Q5SVH9	Gene names	Camk2b, Camk2d
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type II beta chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II subunit beta) (CaMK-II subunit beta).

MAPK3_HUMAN
NC score	0.747314 (rank : 42)	θ value	1.02001e-27 (rank : 153)
Query Neighborhood Hits	2923	Target Neighborhood Hits	807	Shared Neighborhood Hits	762
SwissProt Accessions	Q16644	Gene names	MAPKAPK3
Domain Architecture	No domain graphic available
Description	MAP kinase-activated protein kinase 3 (EC 2.7.11.1) (MAPK-activated protein kinase 3) (MAPKAP kinase 3) (MAPKAPK-3) (Chromosome 3p kinase) (3pK).

CHK2_MOUSE
NC score	0.746258 (rank : 43)	θ value	8.06329e-33 (rank : 111)
Query Neighborhood Hits	2923	Target Neighborhood Hits	860	Shared Neighborhood Hits	787
SwissProt Accessions	Q9Z265	Gene names	Chek2, Chk2, Rad53
Domain Architecture
Description	Serine/threonine-protein kinase Chk2 (EC 2.7.11.1).

CHK2_HUMAN
NC score	0.745284 (rank : 44)	θ value	5.77852e-31 (rank : 125)
Query Neighborhood Hits	2923	Target Neighborhood Hits	859	Shared Neighborhood Hits	790
SwissProt Accessions	O96017, Q6QA03, Q6QA04, Q6QA05, Q6QA06, Q6QA07, Q6QA08, Q6QA10, Q6QA11, Q6QA12, Q6QA13, Q9HCQ8, Q9UGF0, Q9UGF1	Gene names	CHEK2, CHK2
Domain Architecture
Description	Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (Cds1).

STK33_HUMAN
NC score	0.744872 (rank : 45)	θ value	1.92365e-26 (rank : 162)
Query Neighborhood Hits	2923	Target Neighborhood Hits	879	Shared Neighborhood Hits	807
SwissProt Accessions	Q9BYT3, Q658S6, Q8NEF5	Gene names	STK33
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 33 (EC 2.7.11.1).

PHKG2_MOUSE
NC score	0.744113 (rank : 46)	θ value	1.0531e-32 (rank : 113)
Query Neighborhood Hits	2923	Target Neighborhood Hits	841	Shared Neighborhood Hits	788
SwissProt Accessions	Q9DB30	Gene names	Phkg2
Domain Architecture
Description	Phosphorylase b kinase gamma catalytic chain, testis/liver isoform (EC 2.7.11.19) (PHK-gamma-T) (Phosphorylase kinase subunit gamma 2).

PHKG2_HUMAN
NC score	0.743630 (rank : 47)	θ value	2.12192e-33 (rank : 107)
Query Neighborhood Hits	2923	Target Neighborhood Hits	839	Shared Neighborhood Hits	786
SwissProt Accessions	P15735, P11800	Gene names	PHKG2
Domain Architecture
Description	Phosphorylase b kinase gamma catalytic chain, testis/liver isoform (EC 2.7.11.19) (PHK-gamma-T) (Phosphorylase kinase subunit gamma 2) (PSK-C3).

CAMKV_MOUSE
NC score	0.743584 (rank : 48)	θ value	1.6813e-30 (rank : 131)
Query Neighborhood Hits	2923	Target Neighborhood Hits	848	Shared Neighborhood Hits	787
SwissProt Accessions	Q3UHL1, Q8VD20	Gene names	Camkv
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

PTK7_HUMAN
NC score	0.743487 (rank : 49)	θ value	1.28434e-38 (rank : 61)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1103	Shared Neighborhood Hits	1028
SwissProt Accessions	Q13308, Q13417	Gene names	PTK7, CCK4
Domain Architecture
Description	Tyrosine-protein kinase-like 7 precursor (Colon carcinoma kinase 4) (CCK-4).

DCAK1_HUMAN
NC score	0.743179 (rank : 50)	θ value	2.34606e-32 (rank : 114)
Query Neighborhood Hits	2923	Target Neighborhood Hits	877	Shared Neighborhood Hits	798
SwissProt Accessions	O15075	Gene names	DCAMKL1, KIAA0369
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 1).

DCAK1_MOUSE
NC score	0.743010 (rank : 51)	θ value	2.34606e-32 (rank : 115)
Query Neighborhood Hits	2923	Target Neighborhood Hits	867	Shared Neighborhood Hits	791
SwissProt Accessions	Q9JLM8, Q6P207	Gene names	Dcamkl1, Dclk
Domain Architecture
Description	Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 1).

MKNK2_HUMAN
NC score	0.742443 (rank : 52)	θ value	6.82597e-32 (rank : 117)
Query Neighborhood Hits	2923	Target Neighborhood Hits	821	Shared Neighborhood Hits	773
SwissProt Accessions	Q9HBH9, Q6GPI3, Q9HBH8, Q9UHR0, Q9Y2N6	Gene names	MKNK2, MNK2
Domain Architecture
Description	MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 2) (Mnk2).

PHKG1_MOUSE
NC score	0.742410 (rank : 53)	θ value	2.12192e-33 (rank : 106)
Query Neighborhood Hits	2923	Target Neighborhood Hits	840	Shared Neighborhood Hits	780
SwissProt Accessions	P07934	Gene names	Phkg1, Phkg
Domain Architecture
Description	Phosphorylase b kinase gamma catalytic chain, skeletal muscle isoform (EC 2.7.11.19) (Phosphorylase kinase subunit gamma 1).

MKNK2_MOUSE
NC score	0.742114 (rank : 54)	θ value	8.91499e-32 (rank : 118)
Query Neighborhood Hits	2923	Target Neighborhood Hits	819	Shared Neighborhood Hits	772
SwissProt Accessions	Q8CDB0, O08606, Q75PY0, Q9D893	Gene names	Mknk2, Mnk2
Domain Architecture
Description	MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 2) (Mnk2).

DCAK2_MOUSE
NC score	0.742099 (rank : 55)	θ value	4.72714e-33 (rank : 108)
Query Neighborhood Hits	2923	Target Neighborhood Hits	858	Shared Neighborhood Hits	793
SwissProt Accessions	Q6PGN3, Q8BUU0, Q8BX25	Gene names	Dcamkl2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL2 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 2).

DCAK2_HUMAN
NC score	0.741990 (rank : 56)	θ value	4.27553e-34 (rank : 98)
Query Neighborhood Hits	2923	Target Neighborhood Hits	862	Shared Neighborhood Hits	794
SwissProt Accessions	Q8N568, Q8N399	Gene names	DCAMKL2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL2 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 2).

PHKG1_HUMAN
NC score	0.741880 (rank : 57)	θ value	1.9192e-34 (rank : 93)
Query Neighborhood Hits	2923	Target Neighborhood Hits	838	Shared Neighborhood Hits	781
SwissProt Accessions	Q16816	Gene names	PHKG1, PHKG
Domain Architecture
Description	Phosphorylase b kinase gamma catalytic chain, skeletal muscle isoform (EC 2.7.11.19) (Phosphorylase kinase subunit gamma 1).

SNRK_HUMAN
NC score	0.741738 (rank : 58)	θ value	2.27234e-27 (rank : 155)
Query Neighborhood Hits	2923	Target Neighborhood Hits	855	Shared Neighborhood Hits	790
SwissProt Accessions	Q9NRH2, Q14706, Q68D15, Q6IQ46, Q9NXI7	Gene names	SNRK, KIAA0096, SNFRK
Domain Architecture	No domain graphic available
Description	SNF-related serine/threonine-protein kinase (EC 2.7.11.1) (SNF1- related kinase).

CAMKV_HUMAN
NC score	0.741691 (rank : 59)	θ value	1.6813e-30 (rank : 130)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1084	Shared Neighborhood Hits	867
SwissProt Accessions	Q8NCB2, Q6FIB8, Q8NBS8, Q8NC85, Q8NDU4, Q8WTT8, Q9BQC9, Q9H0Q5	Gene names	CAMKV
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

ULK3_MOUSE
NC score	0.741036 (rank : 60)	θ value	2.27234e-27 (rank : 156)
Query Neighborhood Hits	2923	Target Neighborhood Hits	872	Shared Neighborhood Hits	796
SwissProt Accessions	Q3U3Q1, Q8K1X6, Q9DBR8	Gene names	Ulk3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3).

SNRK_MOUSE
NC score	0.740683 (rank : 61)	θ value	1.12775e-26 (rank : 160)
Query Neighborhood Hits	2923	Target Neighborhood Hits	849	Shared Neighborhood Hits	786
SwissProt Accessions	Q8VDU5, Q91WX6	Gene names	Snrk
Domain Architecture	No domain graphic available
Description	SNF-related serine/threonine-protein kinase (EC 2.7.11.1) (SNF1- related kinase).

PLK4_HUMAN
NC score	0.739111 (rank : 62)	θ value	1.24688e-25 (rank : 167)
Query Neighborhood Hits	2923	Target Neighborhood Hits	884	Shared Neighborhood Hits	796
SwissProt Accessions	O00444, Q8IYF0, Q96Q95	Gene names	PLK4, SAK, STK18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine- protein kinase 18).

ULK3_HUMAN
NC score	0.738890 (rank : 63)	θ value	1.5773e-20 (rank : 255)
Query Neighborhood Hits	2923	Target Neighborhood Hits	830	Shared Neighborhood Hits	783
SwissProt Accessions	Q6PHR2, Q9NPN5, Q9UFS4	Gene names	ULK3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3).

PLK4_MOUSE
NC score	0.738884 (rank : 64)	θ value	6.18819e-25 (rank : 179)
Query Neighborhood Hits	2923	Target Neighborhood Hits	879	Shared Neighborhood Hits	796
SwissProt Accessions	Q64702, Q6PEP6, Q78EG6, Q8R0I5, Q9CVR6, Q9CVU6	Gene names	Plk4, Sak, Stk18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine- protein kinase 18).

AURKC_MOUSE
NC score	0.738877 (rank : 65)	θ value	4.9032e-22 (rank : 220)
Query Neighborhood Hits	2923	Target Neighborhood Hits	844	Shared Neighborhood Hits	788
SwissProt Accessions	O88445, Q9JLC2	Gene names	Aurkc, Aie1, Stk13
Domain Architecture
Description	Serine/threonine-protein kinase 13 (EC 2.7.11.1) (Aurora/Ipl1/Eg2 protein 1) (Aurora-C).

MELK_MOUSE
NC score	0.738819 (rank : 66)	θ value	8.08199e-25 (rank : 181)
Query Neighborhood Hits	2923	Target Neighborhood Hits	860	Shared Neighborhood Hits	794
SwissProt Accessions	Q61846, Q61804, Q6ZQH6	Gene names	Melk, Kiaa0175, Pk38
Domain Architecture	No domain graphic available
Description	Maternal embryonic leucine zipper kinase (EC 2.7.11.1) (Protein kinase PK38) (mPK38).

BRSK1_HUMAN
NC score	0.738745 (rank : 67)	θ value	1.80048e-24 (rank : 182)
Query Neighborhood Hits	2923	Target Neighborhood Hits	942	Shared Neighborhood Hits	814
SwissProt Accessions	Q8TDC3, Q5J5B5, Q8NDD0, Q8NDR4, Q8TDC2, Q96AV4, Q96JL4	Gene names	BRSK1, KIAA1811, SAD1
Domain Architecture
Description	BR serine/threonine-protein kinase 1 (EC 2.7.11.1) (SAD1 kinase) (SAD1A).

NUAK2_HUMAN
NC score	0.738565 (rank : 68)	θ value	4.73814e-25 (rank : 176)
Query Neighborhood Hits	2923	Target Neighborhood Hits	874	Shared Neighborhood Hits	796
SwissProt Accessions	Q9H093	Gene names	NUAK2
Domain Architecture	No domain graphic available
Description	NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (SNF1/AMP kinase-related kinase) (SNARK).

MELK_HUMAN
NC score	0.738439 (rank : 69)	θ value	4.01107e-24 (rank : 189)
Query Neighborhood Hits	2923	Target Neighborhood Hits	847	Shared Neighborhood Hits	786
SwissProt Accessions	Q14680, Q7L3C3	Gene names	MELK, KIAA0175
Domain Architecture	No domain graphic available
Description	Maternal embryonic leucine zipper kinase (EC 2.7.11.1) (hMELK) (Protein kinase PK38) (hPK38).

NUAK2_MOUSE
NC score	0.737880 (rank : 70)	θ value	1.16704e-23 (rank : 196)
Query Neighborhood Hits	2923	Target Neighborhood Hits	878	Shared Neighborhood Hits	796
SwissProt Accessions	Q8BZN4, Q80ZW3, Q8CIC0, Q9DBV0	Gene names	Nuak2
Domain Architecture	No domain graphic available
Description	NUAK family SNF1-like kinase 2 (EC 2.7.11.1).

MKNK1_MOUSE
NC score	0.737742 (rank : 71)	θ value	2.59387e-31 (rank : 123)
Query Neighborhood Hits	2923	Target Neighborhood Hits	811	Shared Neighborhood Hits	758
SwissProt Accessions	O08605	Gene names	Mknk1, Mnk1
Domain Architecture
Description	MAP kinase-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (Mnk1).

STK6_MOUSE
NC score	0.737515 (rank : 72)	θ value	7.80994e-28 (rank : 151)
Query Neighborhood Hits	2923	Target Neighborhood Hits	886	Shared Neighborhood Hits	797
SwissProt Accessions	P97477, O35624, Q91YU4	Gene names	Stk6, Ark1, Aurka, Ayk1, Iak1
Domain Architecture
Description	Serine/threonine-protein kinase 6 (EC 2.7.11.1) (Aurora-family kinase 1) (Aurora/IPL1-related kinase 1) (Ipl1- and aurora-related kinase 1) (Aurora-A) (Serine/threonine-protein kinase Ayk1).

BRSK2_HUMAN
NC score	0.737349 (rank : 73)	θ value	5.79196e-23 (rank : 203)
Query Neighborhood Hits	2923	Target Neighborhood Hits	897	Shared Neighborhood Hits	810
SwissProt Accessions	Q8IWQ3, O60843, O95099, Q5J5B4, Q8TB60	Gene names	BRSK2, C11orf7, PEN11B, STK29
Domain Architecture
Description	BR serine/threonine-protein kinase 2 (EC 2.7.11.1) (Serine/threonine- protein kinase 29) (SAD1B).

NIM1_MOUSE
NC score	0.737295 (rank : 74)	θ value	1.80048e-24 (rank : 185)
Query Neighborhood Hits	2923	Target Neighborhood Hits	850	Shared Neighborhood Hits	792
SwissProt Accessions	Q8BHI9, Q8BXQ9	Gene names	NIM1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase NIM1 (EC 2.7.11.1).

STK6_HUMAN
NC score	0.737077 (rank : 75)	θ value	1.62847e-25 (rank : 170)
Query Neighborhood Hits	2923	Target Neighborhood Hits	916	Shared Neighborhood Hits	818
SwissProt Accessions	O14965, O60445, O75873, Q9BQD6, Q9UPG5	Gene names	STK6, AIK, ARK1, AURA, BTAK, STK15
Domain Architecture
Description	Serine/threonine-protein kinase 6 (EC 2.7.11.1) (Serine/threonine kinase 15) (Aurora/IPL1-related kinase 1) (Aurora-related kinase 1) (hARK1) (Aurora-A) (Breast-tumor-amplified kinase).

AURKC_HUMAN
NC score	0.737052 (rank : 76)	θ value	2.87452e-22 (rank : 216)
Query Neighborhood Hits	2923	Target Neighborhood Hits	847	Shared Neighborhood Hits	789
SwissProt Accessions	Q9UQB9, O60681, O75442, Q9UPK5	Gene names	AURKC, AIE2, AIK3, STK13
Domain Architecture
Description	Serine/threonine-protein kinase 13 (EC 2.7.11.1) (Aurora/Ipl1/Eg2 protein 2) (Aurora/Ipl1-related kinase 3) (Aurora-C).

KPCD2_HUMAN
NC score	0.736888 (rank : 77)	θ value	1.2049e-28 (rank : 144)
Query Neighborhood Hits	2923	Target Neighborhood Hits	910	Shared Neighborhood Hits	794
SwissProt Accessions	Q9BZL6, Q8TB08, Q9P0T6, Q9Y3X8	Gene names	PRKD2, PKD2
Domain Architecture
Description	Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2).

NUAK1_MOUSE
NC score	0.736785 (rank : 78)	θ value	1.99067e-23 (rank : 200)
Query Neighborhood Hits	2923	Target Neighborhood Hits	881	Shared Neighborhood Hits	800
SwissProt Accessions	Q641K5, Q6I6D6, Q8CGE1	Gene names	Nuak1, Kiaa0537
Domain Architecture	No domain graphic available
Description	NUAK family SNF1-like kinase 1 (EC 2.7.11.1).

NUAK1_HUMAN
NC score	0.736528 (rank : 79)	θ value	2.59989e-23 (rank : 201)
Query Neighborhood Hits	2923	Target Neighborhood Hits	874	Shared Neighborhood Hits	795
SwissProt Accessions	O60285, Q96KA8	Gene names	NUAK1, ARK5, KIAA0537
Domain Architecture	No domain graphic available
Description	NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase 5).

NIM1_HUMAN
NC score	0.736517 (rank : 80)	θ value	1.80048e-24 (rank : 184)
Query Neighborhood Hits	2923	Target Neighborhood Hits	850	Shared Neighborhood Hits	791
SwissProt Accessions	Q8IY84	Gene names	NIM1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase NIM1 (EC 2.7.11.1).

AURKB_MOUSE
NC score	0.736398 (rank : 81)	θ value	4.15078e-21 (rank : 241)
Query Neighborhood Hits	2923	Target Neighborhood Hits	858	Shared Neighborhood Hits	790
SwissProt Accessions	O70126, Q61882	Gene names	Aurkb, Ark2, Stk1, Stk12, Stk5
Domain Architecture
Description	Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-B) (Aurora- related kinase 2) (Serine/threonine-protein kinase 5) (STK-1).

KPCD1_HUMAN
NC score	0.736215 (rank : 82)	θ value	4.14116e-29 (rank : 142)
Query Neighborhood Hits	2923	Target Neighborhood Hits	901	Shared Neighborhood Hits	792
SwissProt Accessions	Q15139	Gene names	PRKD1, PKD, PKD1, PRKCM
Domain Architecture
Description	Serine/threonine-protein kinase D1 (EC 2.7.11.13) (nPKC-D1) (Protein kinase D) (Protein kinase C mu type) (nPKC-mu).

KS6A1_MOUSE
NC score	0.736082 (rank : 83)	θ value	2.34606e-32 (rank : 116)
Query Neighborhood Hits	2923	Target Neighborhood Hits	850	Shared Neighborhood Hits	794
SwissProt Accessions	P18653	Gene names	Rps6ka1, Rsk1
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1) (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (p90S6K) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A).

KPCD1_MOUSE
NC score	0.735972 (rank : 84)	θ value	4.14116e-29 (rank : 143)
Query Neighborhood Hits	2923	Target Neighborhood Hits	891	Shared Neighborhood Hits	793
SwissProt Accessions	Q62101	Gene names	Prkd1, Pkcm, Pkd, Prkcm
Domain Architecture
Description	Serine/threonine-protein kinase D1 (EC 2.7.11.13) (nPKC-D1) (Protein kinase D) (Protein kinase C mu type) (nPKC-mu).

KPCD3_MOUSE
NC score	0.735971 (rank : 85)	θ value	1.08979e-29 (rank : 136)
Query Neighborhood Hits	2923	Target Neighborhood Hits	901	Shared Neighborhood Hits	792
SwissProt Accessions	Q8K1Y2	Gene names	Prkd3, Prkcn
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (nPKC-nu).

AURKB_HUMAN
NC score	0.735819 (rank : 86)	θ value	7.82807e-20 (rank : 274)
Query Neighborhood Hits	2923	Target Neighborhood Hits	847	Shared Neighborhood Hits	788
SwissProt Accessions	Q96GD4, O14630, O60446, O95083, Q96DV5, Q9UQ46	Gene names	AURKB, AIK2, AIM1, ARK2, STK12
Domain Architecture
Description	Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-B) (Aurora- and Ipl1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1- related kinase 2) (Aurora-related kinase 2) (STK-1).

KPCD3_HUMAN
NC score	0.735481 (rank : 87)	θ value	1.4233e-29 (rank : 139)
Query Neighborhood Hits	2923	Target Neighborhood Hits	895	Shared Neighborhood Hits	790
SwissProt Accessions	O94806	Gene names	PRKD3, EPK2, PRKCN
Domain Architecture
Description	Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (nPKC-nu) (Protein kinase EPK2).

KS6A2_MOUSE
NC score	0.735010 (rank : 88)	θ value	7.54701e-31 (rank : 127)
Query Neighborhood Hits	2923	Target Neighborhood Hits	858	Shared Neighborhood Hits	795
SwissProt Accessions	Q9WUT3, Q9D2C0	Gene names	Rps6ka2, Rsk3
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1) (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (Protein-tyrosine kinase Mpk-9) (MAP kinase- activated protein kinase 1c) (MAPKAPK1C).

PASK_MOUSE
NC score	0.734987 (rank : 89)	θ value	3.17815e-21 (rank : 239)
Query Neighborhood Hits	2923	Target Neighborhood Hits	867	Shared Neighborhood Hits	780
SwissProt Accessions	Q8CEE6, Q91YD8	Gene names	Pask, Kiaa0135
Domain Architecture
Description	PAS domain-containing serine/threonine-protein kinase (EC 2.7.11.1) (PAS-kinase) (PASKIN).

AAPK2_HUMAN
NC score	0.734849 (rank : 90)	θ value	1.09232e-21 (rank : 227)
Query Neighborhood Hits	2923	Target Neighborhood Hits	843	Shared Neighborhood Hits	789
SwissProt Accessions	P54646, Q9H1E8, Q9UD43	Gene names	PRKAA2, AMPK, AMPK2
Domain Architecture
Description	5'-AMP-activated protein kinase catalytic subunit alpha-2 (EC 2.7.11.1) (AMPK alpha-2 chain).

HUNK_MOUSE
NC score	0.734602 (rank : 91)	θ value	1.80466e-16 (rank : 363)
Query Neighborhood Hits	2923	Target Neighborhood Hits	874	Shared Neighborhood Hits	797
SwissProt Accessions	O88866	Gene names	Hunk, Makv
Domain Architecture
Description	Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (Serine/threonine-protein kinase MAK-V).

MAPK5_MOUSE
NC score	0.734441 (rank : 92)	θ value	4.73814e-25 (rank : 175)
Query Neighborhood Hits	2923	Target Neighborhood Hits	799	Shared Neighborhood Hits	756
SwissProt Accessions	O54992, Q6QME4, Q6QME5, Q6QME6, Q6QME7	Gene names	Mapkapk5
Domain Architecture	No domain graphic available
Description	MAP kinase-activated protein kinase 5 (EC 2.7.11.1) (MAPK-activated protein kinase 5) (MAPKAP kinase 5).

HUNK_HUMAN
NC score	0.734417 (rank : 93)	θ value	5.25075e-16 (rank : 378)
Query Neighborhood Hits	2923	Target Neighborhood Hits	884	Shared Neighborhood Hits	800
SwissProt Accessions	P57058	Gene names	HUNK, MAKV
Domain Architecture
Description	Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (Serine/threonine-protein kinase MAK-V) (B19).

KS6A2_HUMAN
NC score	0.734267 (rank : 94)	θ value	1.16434e-31 (rank : 119)
Query Neighborhood Hits	2923	Target Neighborhood Hits	857	Shared Neighborhood Hits	794
SwissProt Accessions	Q15349, Q15419, Q59GJ3, Q5TI68, Q96J38, Q9UJN5	Gene names	RPS6KA2, RSK3
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1) (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (MAP kinase-activated protein kinase 1c) (MAPKAPK1C).

AAPK1_HUMAN
NC score	0.734164 (rank : 95)	θ value	3.17815e-21 (rank : 237)
Query Neighborhood Hits	2923	Target Neighborhood Hits	842	Shared Neighborhood Hits	788
SwissProt Accessions	Q13131, O00286, Q5D0E1, Q9UNQ4	Gene names	PRKAA1, AMPK1
Domain Architecture
Description	5'-AMP-activated protein kinase catalytic subunit alpha-1 (EC 2.7.11.1) (AMPK alpha-1 chain).

SN1L1_HUMAN
NC score	0.734066 (rank : 96)	θ value	1.09232e-21 (rank : 229)
Query Neighborhood Hits	2923	Target Neighborhood Hits	911	Shared Neighborhood Hits	810
SwissProt Accessions	P57059, Q5R2V5, Q86YJ2	Gene names	SNF1LK
Domain Architecture
Description	Serine/threonine-protein kinase SNF1-like kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase SNF1LK).

SN1L1_MOUSE
NC score	0.734056 (rank : 97)	θ value	1.16704e-23 (rank : 197)
Query Neighborhood Hits	2923	Target Neighborhood Hits	895	Shared Neighborhood Hits	808
SwissProt Accessions	Q60670	Gene names	Snf1lk, Msk
Domain Architecture
Description	Serine/threonine-protein kinase SNF1-like kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) (HRT-20) (Myocardial SNF1- like kinase).

KS6A6_HUMAN
NC score	0.734051 (rank : 98)	θ value	3.50572e-28 (rank : 146)
Query Neighborhood Hits	2923	Target Neighborhood Hits	853	Shared Neighborhood Hits	787
SwissProt Accessions	Q9UK32, Q8WX28, Q9H4S6	Gene names	RPS6KA6, RSK4
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-6 (EC 2.7.11.1) (S6K-alpha 6) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4).

STK11_HUMAN
NC score	0.733980 (rank : 99)	θ value	5.42112e-21 (rank : 245)
Query Neighborhood Hits	2923	Target Neighborhood Hits	831	Shared Neighborhood Hits	779
SwissProt Accessions	Q15831	Gene names	STK11, LKB1, PJS
Domain Architecture
Description	Serine/threonine-protein kinase 11 (EC 2.7.11.1) (Serine/threonine- protein kinase LKB1) (NY-REN-19 antigen).

AAPK1_MOUSE
NC score	0.733900 (rank : 100)	θ value	1.2077e-20 (rank : 250)
Query Neighborhood Hits	2923	Target Neighborhood Hits	843	Shared Neighborhood Hits	788
SwissProt Accessions	Q5EG47	Gene names	Prkaa1
Domain Architecture	No domain graphic available
Description	5'-AMP-activated protein kinase catalytic subunit alpha-1 (EC 2.7.11.1) (AMPK alpha-1 chain).

KS6A1_HUMAN
NC score	0.733753 (rank : 101)	θ value	2.59387e-31 (rank : 122)
Query Neighborhood Hits	2923	Target Neighborhood Hits	854	Shared Neighborhood Hits	794
SwissProt Accessions	Q15418, Q5SVM5, Q5SVM8, Q5SVM9, Q96C05, Q9BQK2	Gene names	RPS6KA1, RSK1
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1) (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (p90S6K) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A).

SN1L2_HUMAN
NC score	0.733489 (rank : 102)	θ value	1.5773e-20 (rank : 253)
Query Neighborhood Hits	2923	Target Neighborhood Hits	964	Shared Neighborhood Hits	855
SwissProt Accessions	Q9H0K1, O94878, Q6AZE2, Q76N03, Q8NCV7, Q96CZ8	Gene names	SNF1LK2, KIAA0781, QIK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SNF1-like kinase 2 (EC 2.7.11.1) (Qin- induced kinase).

MAPK5_HUMAN
NC score	0.733371 (rank : 103)	θ value	6.18819e-25 (rank : 178)
Query Neighborhood Hits	2923	Target Neighborhood Hits	795	Shared Neighborhood Hits	752
SwissProt Accessions	Q8IW41, O60491, Q86X46, Q9BVX9, Q9UG86	Gene names	MAPKAPK5, PRAK
Domain Architecture	No domain graphic available
Description	MAP kinase-activated protein kinase 5 (EC 2.7.11.1) (MAPK-activated protein kinase 5) (MAPKAP kinase 5) (p38-regulated/activated protein kinase).

KS6A3_HUMAN
NC score	0.733321 (rank : 104)	θ value	1.28732e-30 (rank : 128)
Query Neighborhood Hits	2923	Target Neighborhood Hits	859	Shared Neighborhood Hits	795
SwissProt Accessions	P51812, Q4VAP3, Q59H26, Q5JPK8, Q7Z3Z7	Gene names	RPS6KA3, ISPK1, RSK2
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1) (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B).

KS6A3_MOUSE
NC score	0.733265 (rank : 105)	θ value	1.28732e-30 (rank : 129)
Query Neighborhood Hits	2923	Target Neighborhood Hits	860	Shared Neighborhood Hits	795
SwissProt Accessions	P18654, Q03140, Q8K3J8	Gene names	Rps6ka3, Rps6ka-rs1, Rsk2
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1) (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B).

PLK1_MOUSE
NC score	0.732993 (rank : 106)	θ value	1.38178e-16 (rank : 361)
Query Neighborhood Hits	2923	Target Neighborhood Hits	849	Shared Neighborhood Hits	784
SwissProt Accessions	Q07832	Gene names	Plk1, Plk
Domain Architecture
Description	Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13).

ULK2_MOUSE
NC score	0.732899 (rank : 107)	θ value	3.07116e-24 (rank : 188)
Query Neighborhood Hits	2923	Target Neighborhood Hits	943	Shared Neighborhood Hits	823
SwissProt Accessions	Q9QY01, Q80TV7, Q9WTP4	Gene names	Ulk2, Kiaa0623
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2) (Serine/threonine-protein kinase Unc51.2).

K0999_MOUSE
NC score	0.732888 (rank : 108)	θ value	6.84181e-24 (rank : 193)
Query Neighborhood Hits	2923	Target Neighborhood Hits	931	Shared Neighborhood Hits	811
SwissProt Accessions	Q6P4S6, Q641L5, Q66JZ5, Q6ZQ09, Q8K075, Q9CYD5	Gene names	Kiaa0999
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase KIAA0999 (EC 2.7.11.1).

K0999_HUMAN
NC score	0.732853 (rank : 109)	θ value	8.93572e-24 (rank : 195)
Query Neighborhood Hits	2923	Target Neighborhood Hits	899	Shared Neighborhood Hits	801
SwissProt Accessions	Q9Y2K2, Q59FY2, Q5M9N1, Q6P3R6, Q8IYM8, Q9HA50	Gene names	KIAA0999
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase KIAA0999 (EC 2.7.11.1).

KKCC2_HUMAN
NC score	0.732850 (rank : 110)	θ value	2.60593e-15 (rank : 404)
Query Neighborhood Hits	2923	Target Neighborhood Hits	852	Shared Neighborhood Hits	782
SwissProt Accessions	Q96RR4, O94883, Q8IUG2, Q8IUG3, Q8N3I4, Q8WY03, Q8WY04, Q8WY05, Q8WY06, Q96RP1, Q96RP2, Q96RR3, Q9BWE9, Q9UER3, Q9UES2, Q9Y5N2	Gene names	CAMKK2, CAMKKB, KIAA0787
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase kinase 2 (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta).

KKCC2_MOUSE
NC score	0.732813 (rank : 111)	θ value	7.58209e-15 (rank : 420)
Query Neighborhood Hits	2923	Target Neighborhood Hits	855	Shared Neighborhood Hits	784
SwissProt Accessions	Q8C078, Q80TS0, Q8BXM8, Q8C0G3, Q8CH42, Q8QZT7	Gene names	Camkk2, Kiaa0787
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase kinase 2 (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta).

PASK_HUMAN
NC score	0.732734 (rank : 112)	θ value	2.06002e-20 (rank : 258)
Query Neighborhood Hits	2923	Target Neighborhood Hits	857	Shared Neighborhood Hits	776
SwissProt Accessions	Q96RG2, Q86XH6, Q99763, Q9UFR7	Gene names	PASK, KIAA0135
Domain Architecture
Description	PAS domain-containing serine/threonine-protein kinase (EC 2.7.11.1) (PAS-kinase) (PASKIN) (hPASK).

KKCC1_MOUSE
NC score	0.732635 (rank : 113)	θ value	3.07829e-16 (rank : 371)
Query Neighborhood Hits	2923	Target Neighborhood Hits	866	Shared Neighborhood Hits	793
SwissProt Accessions	Q8VBY2, Q9R054	Gene names	Camkk1, Camkk
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase kinase 1 (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-kinase kinase alpha) (CaM-KK alpha) (CaMKK alpha) (CaMKK 1) (CaM-kinase IV kinase).

PLK1_HUMAN
NC score	0.732543 (rank : 114)	θ value	2.35696e-16 (rank : 368)
Query Neighborhood Hits	2923	Target Neighborhood Hits	849	Shared Neighborhood Hits	784
SwissProt Accessions	P53350, Q15153, Q99746	Gene names	PLK1, PLK
Domain Architecture
Description	Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13).

ULK2_HUMAN
NC score	0.732458 (rank : 115)	θ value	4.01107e-24 (rank : 191)
Query Neighborhood Hits	2923	Target Neighborhood Hits	979	Shared Neighborhood Hits	826
SwissProt Accessions	Q8IYT8, O75119	Gene names	ULK2, KIAA0623
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2).

SN1L2_MOUSE
NC score	0.732439 (rank : 116)	θ value	2.69047e-20 (rank : 260)
Query Neighborhood Hits	2923	Target Neighborhood Hits	944	Shared Neighborhood Hits	841
SwissProt Accessions	Q8CFH6	Gene names	Snf1lk2, Sik2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SNF1-like kinase 2 (EC 2.7.11.1) (Salt-inducible kinase 2).

KKCC1_HUMAN
NC score	0.732338 (rank : 117)	θ value	3.07829e-16 (rank : 370)
Query Neighborhood Hits	2923	Target Neighborhood Hits	858	Shared Neighborhood Hits	786
SwissProt Accessions	Q8N5S9, Q9BQH3	Gene names	CAMKK1, CAMKKA
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase kinase 1 (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-kinase kinase alpha) (CaM-KK alpha) (CaMKK alpha) (CaMKK 1) (CaM-kinase IV kinase).

SBK1_MOUSE
NC score	0.731997 (rank : 118)	θ value	2.88119e-14 (rank : 443)
Query Neighborhood Hits	2923	Target Neighborhood Hits	824	Shared Neighborhood Hits	774
SwissProt Accessions	Q8QZX0	Gene names	Sbk1, Sbk
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SBK1 (EC 2.7.11.1) (SH3-binding kinase 1).

STK36_HUMAN
NC score	0.731938 (rank : 119)	θ value	1.62847e-25 (rank : 169)
Query Neighborhood Hits	2923	Target Neighborhood Hits	896	Shared Neighborhood Hits	801
SwissProt Accessions	Q9NRP7, Q8TC32, Q9H9N9, Q9UF35, Q9ULE2	Gene names	STK36, KIAA1278
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog).

TSSK6_MOUSE
NC score	0.731461 (rank : 120)	θ value	2.98157e-11 (rank : 589)
Query Neighborhood Hits	2923	Target Neighborhood Hits	824	Shared Neighborhood Hits	783
SwissProt Accessions	Q925K9, Q5RL09, Q8C625	Gene names	Tssk6, Sstk
Domain Architecture	No domain graphic available
Description	Testis-specific serine/threonine-protein kinase 6 (EC 2.7.11.1) (TSSK- 6) (Small serine/threonine kinase) (Serine/threonine-protein kinase SSTK).

SBK1_HUMAN
NC score	0.731394 (rank : 121)	θ value	6.41864e-14 (rank : 460)
Query Neighborhood Hits	2923	Target Neighborhood Hits	828	Shared Neighborhood Hits	777
SwissProt Accessions	Q52WX2	Gene names	SBK1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SBK1 (EC 2.7.11.1) (SH3-binding kinase 1).

PLK3_HUMAN
NC score	0.731137 (rank : 122)	θ value	3.07829e-16 (rank : 374)
Query Neighborhood Hits	2923	Target Neighborhood Hits	865	Shared Neighborhood Hits	791
SwissProt Accessions	Q9H4B4, Q15767, Q96CV1	Gene names	PLK3, CNK, FNK, PRK
Domain Architecture
Description	Serine/threonine-protein kinase PLK3 (EC 2.7.11.21) (Polo-like kinase 3) (PLK-3) (Cytokine-inducible serine/threonine-protein kinase) (FGF- inducible kinase) (Proliferation-related kinase).

PLK3_MOUSE
NC score	0.731093 (rank : 123)	θ value	6.85773e-16 (rank : 386)
Query Neighborhood Hits	2923	Target Neighborhood Hits	863	Shared Neighborhood Hits	791
SwissProt Accessions	Q60806, Q60822, Q9R009	Gene names	Plk3, Cnk, Fnk
Domain Architecture
Description	Serine/threonine-protein kinase PLK3 (EC 2.7.11.21) (Polo-like kinase 3) (PLK-3) (Cytokine-inducible serine/threonine-protein kinase) (FGF- inducible kinase).

PDPK1_HUMAN
NC score	0.730917 (rank : 124)	θ value	1.33526e-19 (rank : 279)
Query Neighborhood Hits	2923	Target Neighborhood Hits	851	Shared Neighborhood Hits	789
SwissProt Accessions	O15530	Gene names	PDPK1, PDK1
Domain Architecture
Description	3-phosphoinositide-dependent protein kinase 1 (EC 2.7.11.1) (hPDK1).

PDPK1_MOUSE
NC score	0.730744 (rank : 125)	θ value	1.74391e-19 (rank : 281)
Query Neighborhood Hits	2923	Target Neighborhood Hits	852	Shared Neighborhood Hits	789
SwissProt Accessions	Q9Z2A0, Q9R1D8, Q9R215	Gene names	Pdpk1, Pdk1
Domain Architecture
Description	3-phosphoinositide-dependent protein kinase 1 (EC 2.7.11.1) (mPDK1).

TSSK6_HUMAN
NC score	0.730684 (rank : 126)	θ value	1.47974e-10 (rank : 632)
Query Neighborhood Hits	2923	Target Neighborhood Hits	824	Shared Neighborhood Hits	784
SwissProt Accessions	Q9BXA6, Q6ZMC4, Q96LJ4	Gene names	TSSK6, FKSG82, SSTK
Domain Architecture	No domain graphic available
Description	Testis-specific serine/threonine-protein kinase 6 (EC 2.7.11.1) (TSSK- 6) (Small serine/threonine kinase) (Serine/threonine-protein kinase SSTK).

KS6A5_HUMAN
NC score	0.730445 (rank : 127)	θ value	1.08979e-29 (rank : 137)
Query Neighborhood Hits	2923	Target Neighborhood Hits	855	Shared Neighborhood Hits	791
SwissProt Accessions	O75582, O95316, Q96AF7	Gene names	RPS6KA5, MSK1
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear mitogen- and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RSKL).

ULK1_HUMAN
NC score	0.730301 (rank : 128)	θ value	3.75424e-22 (rank : 219)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1121	Shared Neighborhood Hits	865
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).

MARK4_HUMAN
NC score	0.730068 (rank : 129)	θ value	3.88503e-19 (rank : 291)
Query Neighborhood Hits	2923	Target Neighborhood Hits	886	Shared Neighborhood Hits	805
SwissProt Accessions	Q96L34, Q8NG37, Q96JG7, Q96SQ2, Q9BYD8	Gene names	MARK4, KIAA1860, MARKL1
Domain Architecture
Description	MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase-like 1).

MARK4_MOUSE
NC score	0.729839 (rank : 130)	θ value	3.88503e-19 (rank : 292)
Query Neighborhood Hits	2923	Target Neighborhood Hits	898	Shared Neighborhood Hits	807
SwissProt Accessions	Q8CIP4, Q80T81	Gene names	Mark4, Kiaa1860
Domain Architecture	No domain graphic available
Description	MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1).

MARK2_HUMAN
NC score	0.729811 (rank : 131)	θ value	2.06002e-20 (rank : 256)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1056	Shared Neighborhood Hits	861
SwissProt Accessions	Q7KZI7, Q15449, Q15524, Q5XGA3, Q68A18, Q96HB3, Q96RG0	Gene names	MARK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog).

TSSK1_MOUSE
NC score	0.729777 (rank : 132)	θ value	2.7842e-17 (rank : 346)
Query Neighborhood Hits	2923	Target Neighborhood Hits	835	Shared Neighborhood Hits	776
SwissProt Accessions	Q61241	Gene names	Tssk1, Stk22a
Domain Architecture
Description	Testis-specific serine/threonine-protein kinase 1 (EC 2.7.11.1) (TSSK- 1) (Testis-specific kinase 1) (TSK-1) (Serine/threonine-protein kinase 22A).

PLK2_HUMAN
NC score	0.729694 (rank : 133)	θ value	1.74391e-19 (rank : 282)
Query Neighborhood Hits	2923	Target Neighborhood Hits	854	Shared Neighborhood Hits	785
SwissProt Accessions	Q9NYY3, O60679, Q96CV7, Q9UE61	Gene names	PLK2, SNK
Domain Architecture
Description	Serine/threonine-protein kinase PLK2 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-2) (Serine/threonine-protein kinase SNK) (Serum-inducible kinase).

TSSK2_HUMAN
NC score	0.729546 (rank : 134)	θ value	3.07829e-16 (rank : 376)
Query Neighborhood Hits	2923	Target Neighborhood Hits	826	Shared Neighborhood Hits	771
SwissProt Accessions	Q96PF2, Q8IY55	Gene names	TSSK2, DGSG, SPOGA2, STK22B
Domain Architecture
Description	Testis-specific serine/threonine-protein kinase 2 (EC 2.7.11.1) (TSSK- 2) (Testis-specific kinase 2) (TSK-2) (Serine/threonine-protein kinase 22B) (DiGeorge syndrome protein G).

STK36_MOUSE
NC score	0.729450 (rank : 135)	θ value	1.86321e-21 (rank : 236)
Query Neighborhood Hits	2923	Target Neighborhood Hits	877	Shared Neighborhood Hits	799
SwissProt Accessions	Q69ZM6, Q6PDI0, Q80XQ6	Gene names	Stk36, Kiaa1278
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog).

PLK2_MOUSE
NC score	0.729383 (rank : 136)	θ value	2.97466e-19 (rank : 288)
Query Neighborhood Hits	2923	Target Neighborhood Hits	849	Shared Neighborhood Hits	784
SwissProt Accessions	P53351	Gene names	Plk2, Snk
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PLK2 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-2) (Serine/threonine-protein kinase SNK) (Serum-inducible kinase).

PRKY_HUMAN
NC score	0.729091 (rank : 137)	θ value	1.92812e-18 (rank : 308)
Query Neighborhood Hits	2923	Target Neighborhood Hits	844	Shared Neighborhood Hits	785
SwissProt Accessions	O43930, O15348, O15349	Gene names	PRKY
Domain Architecture
Description	Serine/threonine-protein kinase PRKY (EC 2.7.11.1).

MARK2_MOUSE
NC score	0.729063 (rank : 138)	θ value	7.82807e-20 (rank : 275)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1018	Shared Neighborhood Hits	854
SwissProt Accessions	Q05512, Q6PDR4, Q8BR95	Gene names	Mark2, Emk
Domain Architecture
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1).

ULK1_MOUSE
NC score	0.728987 (rank : 139)	θ value	1.29031e-22 (rank : 209)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1214	Shared Neighborhood Hits	905
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

MARK3_MOUSE
NC score	0.728840 (rank : 140)	θ value	9.24701e-21 (rank : 248)
Query Neighborhood Hits	2923	Target Neighborhood Hits	919	Shared Neighborhood Hits	816
SwissProt Accessions	Q03141, Q3TM40, Q3V1U3, Q8C6G9, Q8R375, Q9JKE4	Gene names	Mark3, Emk2, Mpk10
Domain Architecture	No domain graphic available
Description	MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (MPK-10) (ELKL motif kinase 2).

KAPCG_HUMAN
NC score	0.728734 (rank : 141)	θ value	5.07402e-19 (rank : 295)
Query Neighborhood Hits	2923	Target Neighborhood Hits	845	Shared Neighborhood Hits	788
SwissProt Accessions	P22612, O60850, Q86YI1	Gene names	PRKACG
Domain Architecture
Description	cAMP-dependent protein kinase, gamma-catalytic subunit (EC 2.7.11.11) (PKA C-gamma).

CHK1_MOUSE
NC score	0.728184 (rank : 142)	θ value	6.85773e-16 (rank : 384)
Query Neighborhood Hits	2923	Target Neighborhood Hits	839	Shared Neighborhood Hits	780
SwissProt Accessions	O35280, O54925, Q8CI40, Q9D0N2	Gene names	Chek1, Chk1
Domain Architecture
Description	Serine/threonine-protein kinase Chk1 (EC 2.7.11.1).

MARK1_HUMAN
NC score	0.728160 (rank : 143)	θ value	4.58923e-20 (rank : 267)
Query Neighborhood Hits	2923	Target Neighborhood Hits	887	Shared Neighborhood Hits	804
SwissProt Accessions	Q9P0L2, Q5VTF9, Q5VTG0, Q96SW9, Q9P251	Gene names	MARK1, KIAA1477, MARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MARK1 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 1).

MARK1_MOUSE
NC score	0.728137 (rank : 144)	θ value	4.58923e-20 (rank : 268)
Query Neighborhood Hits	2923	Target Neighborhood Hits	886	Shared Neighborhood Hits	803
SwissProt Accessions	Q8VHJ5, Q69ZI7	Gene names	Mark1, Emk3, Kiaa1477
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MARK1 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 1) (ELKL motif serine/threonine-protein kinase 3).

TSSK1_HUMAN
NC score	0.728080 (rank : 145)	θ value	1.16975e-15 (rank : 396)
Query Neighborhood Hits	2923	Target Neighborhood Hits	840	Shared Neighborhood Hits	779
SwissProt Accessions	Q9BXA7	Gene names	TSSK1, SPOGA1, SPOGA4, STK22A, STK22D
Domain Architecture
Description	Testis-specific serine/threonine-protein kinase 1 (EC 2.7.11.1) (TSSK- 1) (Testis-specific kinase 1) (TSK-1) (Serine/threonine-protein kinase 22A).

CHK1_HUMAN
NC score	0.727707 (rank : 146)	θ value	1.16975e-15 (rank : 395)
Query Neighborhood Hits	2923	Target Neighborhood Hits	843	Shared Neighborhood Hits	782
SwissProt Accessions	O14757	Gene names	CHEK1, CHK1
Domain Architecture
Description	Serine/threonine-protein kinase Chk1 (EC 2.7.11.1).

KAPCA_MOUSE
NC score	0.727505 (rank : 147)	θ value	5.60996e-18 (rank : 326)
Query Neighborhood Hits	2923	Target Neighborhood Hits	836	Shared Neighborhood Hits	786
SwissProt Accessions	P05132, Q9JID0	Gene names	Prkaca, Pkaca
Domain Architecture
Description	cAMP-dependent protein kinase, alpha-catalytic subunit (EC 2.7.11.11) (PKA C-alpha).

KAPCA_HUMAN
NC score	0.726984 (rank : 148)	θ value	2.13179e-17 (rank : 344)
Query Neighborhood Hits	2923	Target Neighborhood Hits	838	Shared Neighborhood Hits	786
SwissProt Accessions	P17612, Q9H2Y0, Q9NRB4, Q9NRH9	Gene names	PRKACA, PKACA
Domain Architecture
Description	cAMP-dependent protein kinase, alpha-catalytic subunit (EC 2.7.11.11) (PKA C-alpha).

KAPCB_HUMAN
NC score	0.726827 (rank : 149)	θ value	5.60996e-18 (rank : 327)
Query Neighborhood Hits	2923	Target Neighborhood Hits	837	Shared Neighborhood Hits	785
SwissProt Accessions	P22694, Q59GC0, Q5BNE9, Q5BNF0, Q5BNF1, Q5BNF2, Q5BNF3, Q5CZ92, Q5T1K3, Q7Z3M1, Q8IYR5, Q8IZQ0	Gene names	PRKACB
Domain Architecture
Description	cAMP-dependent protein kinase, beta-catalytic subunit (EC 2.7.11.11) (PKA C-beta).

KAPCB_MOUSE
NC score	0.726688 (rank : 150)	θ value	2.5182e-18 (rank : 312)
Query Neighborhood Hits	2923	Target Neighborhood Hits	836	Shared Neighborhood Hits	785
SwissProt Accessions	P68181, P05206, Q3TQH5, Q3UDD0, Q3UTH5	Gene names	Prkacb, Pkacb
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase, beta-catalytic subunit (EC 2.7.11.11) (PKA C-beta).

TSSK2_MOUSE
NC score	0.726653 (rank : 151)	θ value	1.29331e-14 (rank : 432)
Query Neighborhood Hits	2923	Target Neighborhood Hits	819	Shared Neighborhood Hits	765
SwissProt Accessions	O54863	Gene names	Tssk2, Stk22b
Domain Architecture
Description	Testis-specific serine/threonine-protein kinase 2 (EC 2.7.11.1) (TSSK- 2) (Testis-specific kinase 2) (TSK-2) (Serine/threonine-protein kinase 22B).

KS6A4_MOUSE
NC score	0.726584 (rank : 152)	θ value	5.79196e-23 (rank : 204)
Query Neighborhood Hits	2923	Target Neighborhood Hits	866	Shared Neighborhood Hits	793
SwissProt Accessions	Q9Z2B9, Q91X18	Gene names	Rps6ka4, Msk2
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-4 (EC 2.7.11.1) (Nuclear mitogen- and stress-activated protein kinase 2) (90 kDa ribosomal protein S6 kinase 4) (RSK-like protein kinase) (RLSK).

MARK3_HUMAN
NC score	0.726464 (rank : 153)	θ value	1.24977e-17 (rank : 339)
Query Neighborhood Hits	2923	Target Neighborhood Hits	893	Shared Neighborhood Hits	803
SwissProt Accessions	P27448, O60219, Q8TB41, Q8WX83, Q96RG1, Q9UMY9, Q9UN34	Gene names	MARK3, CTAK1
Domain Architecture
Description	MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (Cdc25C- associated protein kinase 1) (cTAK1) (C-TAK1) (Serine/threonine protein kinase p78) (Ser/Thr protein kinase PAR-1) (Protein kinase STK10).

PRKX_MOUSE
NC score	0.726439 (rank : 154)	θ value	3.51386e-20 (rank : 263)
Query Neighborhood Hits	2923	Target Neighborhood Hits	846	Shared Neighborhood Hits	789
SwissProt Accessions	Q922R0, Q3UCD1, Q8BHD6, Q9QZ12	Gene names	Prkx, Pkare
Domain Architecture
Description	Serine/threonine-protein kinase PRKX (EC 2.7.11.1) (PKA-related protein kinase).

TSSK3_MOUSE
NC score	0.726242 (rank : 155)	θ value	2.7842e-17 (rank : 347)
Query Neighborhood Hits	2923	Target Neighborhood Hits	806	Shared Neighborhood Hits	757
SwissProt Accessions	Q9D2E1, Q9JL98	Gene names	Tssk3, Stk22c, Stk22d
Domain Architecture
Description	Testis-specific serine/threonine-protein kinase 3 (EC 2.7.11.1) (TSSK- 3) (Testis-specific kinase 3) (TSK-3) (Serine/threonine-protein kinase 22C).

TSSK3_HUMAN
NC score	0.726181 (rank : 156)	θ value	3.63628e-17 (rank : 350)
Query Neighborhood Hits	2923	Target Neighborhood Hits	806	Shared Neighborhood Hits	756
SwissProt Accessions	Q96PN8	Gene names	TSSK3, SPOGA3, STK22C
Domain Architecture
Description	Testis-specific serine/threonine-protein kinase 3 (EC 2.7.11.1) (TSSK- 3) (Testis-specific kinase 3) (TSK-3) (Serine/threonine-protein kinase 22C).

TSSK4_MOUSE
NC score	0.726156 (rank : 157)	θ value	1.99529e-15 (rank : 400)
Query Neighborhood Hits	2923	Target Neighborhood Hits	840	Shared Neighborhood Hits	779
SwissProt Accessions	Q9D411	Gene names	Tssk4
Domain Architecture	No domain graphic available
Description	Testis-specific serine/threonine-protein kinase 4 (EC 2.7.11.1) (TSSK- 4) (Testis-specific kinase 4) (TSK-4).

KS6A4_HUMAN
NC score	0.725967 (rank : 158)	θ value	1.6852e-22 (rank : 210)
Query Neighborhood Hits	2923	Target Neighborhood Hits	868	Shared Neighborhood Hits	792
SwissProt Accessions	O75676, O75585, Q53ES8	Gene names	RPS6KA4, MSK2
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-4 (EC 2.7.11.1) (Nuclear mitogen- and stress-activated protein kinase 2) (90 kDa ribosomal protein S6 kinase 4) (Ribosomal protein kinase B) (RSKB).

PRKX_HUMAN
NC score	0.724984 (rank : 159)	θ value	3.17815e-21 (rank : 240)
Query Neighborhood Hits	2923	Target Neighborhood Hits	847	Shared Neighborhood Hits	786
SwissProt Accessions	P51817	Gene names	PRKX, PKX1
Domain Architecture
Description	Serine/threonine-protein kinase PRKX (EC 2.7.11.1) (Protein kinase PKX1).

KS6B1_MOUSE
NC score	0.724703 (rank : 160)	θ value	5.99374e-20 (rank : 272)
Query Neighborhood Hits	2923	Target Neighborhood Hits	849	Shared Neighborhood Hits	787
SwissProt Accessions	Q8BSK8, Q8CHX0	Gene names	Rps6kb1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1) (Ribosomal protein S6 kinase I) (S6K) (S6K1) (70 kDa ribosomal protein S6 kinase 1) (p70 S6 kinase alpha) (p70(S6K)-alpha) (p70-S6K) (P70S6K).

KS6B1_HUMAN
NC score	0.724699 (rank : 161)	θ value	5.99374e-20 (rank : 271)
Query Neighborhood Hits	2923	Target Neighborhood Hits	850	Shared Neighborhood Hits	787
SwissProt Accessions	P23443	Gene names	RPS6KB1
Domain Architecture
Description	Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1) (Ribosomal protein S6 kinase I) (S6K) (S6K1) (70 kDa ribosomal protein S6 kinase 1) (p70 S6 kinase alpha) (p70(S6K)-alpha) (p70-S6K) (P70S6K) (p70-alpha).

KS6B2_HUMAN
NC score	0.724365 (rank : 162)	θ value	7.32683e-18 (rank : 333)
Query Neighborhood Hits	2923	Target Neighborhood Hits	858	Shared Neighborhood Hits	796
SwissProt Accessions	Q9UBS0, O94809, Q9UEC1	Gene names	RPS6KB2, STK14B
Domain Architecture
Description	Ribosomal protein S6 kinase beta-2 (EC 2.7.11.1) (S6K2) (70 kDa ribosomal protein S6 kinase 2) (p70-S6KB) (p70 ribosomal S6 kinase beta) (p70 S6Kbeta) (p70 S6 kinase beta) (S6K-beta) (p70-beta) (S6 kinase-related kinase) (SRK) (Serine/threonine-protein kinase 14 beta).

TSSK4_HUMAN
NC score	0.724194 (rank : 163)	θ value	2.20605e-14 (rank : 439)
Query Neighborhood Hits	2923	Target Neighborhood Hits	836	Shared Neighborhood Hits	783
SwissProt Accessions	Q6SA08	Gene names	TSSK4, C14orf20, STK22E
Domain Architecture	No domain graphic available
Description	Testis-specific serine/threonine-protein kinase 4 (EC 2.7.11.1) (TSSK- 4) (Testis-specific kinase 4) (TSK-4) (Serine/threonine-protein kinase 22E).

NEK3_MOUSE
NC score	0.723506 (rank : 164)	θ value	2.06002e-20 (rank : 257)
Query Neighborhood Hits	2923	Target Neighborhood Hits	854	Shared Neighborhood Hits	793
SwissProt Accessions	Q9R0A5, Q9Z0X9	Gene names	Nek3
Domain Architecture
Description	Serine/threonine-protein kinase Nek3 (EC 2.7.11.1) (NimA-related protein kinase 3).

KS6B2_MOUSE
NC score	0.723299 (rank : 165)	θ value	2.5182e-18 (rank : 316)
Query Neighborhood Hits	2923	Target Neighborhood Hits	871	Shared Neighborhood Hits	799
SwissProt Accessions	Q9Z1M4	Gene names	Rps6kb2
Domain Architecture
Description	Ribosomal protein S6 kinase beta-2 (EC 2.7.11.1) (S6K-beta 2) (70 kDa ribosomal protein S6 kinase 2) (p70-S6KB) (p70 ribosomal S6 kinase beta) (p70 S6Kbeta) (S6K2).

PAK6_HUMAN
NC score	0.722729 (rank : 166)	θ value	6.84181e-24 (rank : 194)
Query Neighborhood Hits	2923	Target Neighborhood Hits	915	Shared Neighborhood Hits	832
SwissProt Accessions	Q9NQU5	Gene names	PAK6, PAK5
Domain Architecture
Description	Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1) (p21-activated kinase 6) (PAK-6) (PAK-5).

NEK1_MOUSE
NC score	0.722421 (rank : 167)	θ value	1.09232e-21 (rank : 228)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1311	Shared Neighborhood Hits	995
SwissProt Accessions	P51954	Gene names	Nek1
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1).

AKT3_HUMAN
NC score	0.722391 (rank : 168)	θ value	2.87452e-22 (rank : 214)
Query Neighborhood Hits	2923	Target Neighborhood Hits	872	Shared Neighborhood Hits	789
SwissProt Accessions	Q9Y243, Q96QV3, Q9UFP5	Gene names	AKT3
Domain Architecture
Description	RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) (STK-2).

AKT3_MOUSE
NC score	0.722375 (rank : 169)	θ value	2.87452e-22 (rank : 215)
Query Neighborhood Hits	2923	Target Neighborhood Hits	872	Shared Neighborhood Hits	789
SwissProt Accessions	Q9WUA6	Gene names	Akt3
Domain Architecture
Description	RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma).

PIM2_HUMAN
NC score	0.722307 (rank : 170)	θ value	2.60593e-15 (rank : 405)
Query Neighborhood Hits	2923	Target Neighborhood Hits	808	Shared Neighborhood Hits	764
SwissProt Accessions	Q9P1W9, Q99739	Gene names	PIM2
Domain Architecture
Description	Serine/threonine-protein kinase Pim-2 (EC 2.7.11.1) (Pim-2h).

KS6A5_MOUSE
NC score	0.722061 (rank : 171)	θ value	3.17815e-21 (rank : 238)
Query Neighborhood Hits	2923	Target Neighborhood Hits	854	Shared Neighborhood Hits	791
SwissProt Accessions	Q8C050, Q8CI92	Gene names	Rps6ka5, Msk1
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear mitogen- and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RLSK).

AKT2_HUMAN
NC score	0.721903 (rank : 172)	θ value	1.29031e-22 (rank : 208)
Query Neighborhood Hits	2923	Target Neighborhood Hits	878	Shared Neighborhood Hits	785
SwissProt Accessions	P31751, Q68GC0	Gene names	AKT2
Domain Architecture
Description	RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta).

NEK3_HUMAN
NC score	0.721877 (rank : 173)	θ value	4.74913e-17 (rank : 351)
Query Neighborhood Hits	2923	Target Neighborhood Hits	865	Shared Neighborhood Hits	801
SwissProt Accessions	P51956, Q8WUN5	Gene names	NEK3
Domain Architecture
Description	Serine/threonine-protein kinase Nek3 (EC 2.7.11.1) (NimA-related protein kinase 3) (HSPK 36).

NEK1_HUMAN
NC score	0.721604 (rank : 174)	θ value	2.87452e-22 (rank : 218)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1129	Shared Neighborhood Hits	929
SwissProt Accessions	Q96PY6, Q9Y594	Gene names	NEK1, KIAA1901
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1) (NY-REN-55 antigen).

PIM2_MOUSE
NC score	0.721401 (rank : 175)	θ value	1.29331e-14 (rank : 430)
Query Neighborhood Hits	2923	Target Neighborhood Hits	809	Shared Neighborhood Hits	763
SwissProt Accessions	Q62070, Q62071, Q62072	Gene names	Pim2, Pim-2
Domain Architecture
Description	Serine/threonine-protein kinase Pim-2 (EC 2.7.11.1).

ULK4_MOUSE
NC score	0.721380 (rank : 176)	θ value	7.58209e-15 (rank : 421)
Query Neighborhood Hits	2923	Target Neighborhood Hits	793	Shared Neighborhood Hits	752
SwissProt Accessions	Q3V129, Q2VP87, Q32LZ6, Q8BLS0, Q8C8Z5, Q9D4H6	Gene names	Ulk4
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK4 (EC 2.7.11.1) (Unc-51-like kinase 4).

AKT2_MOUSE
NC score	0.721121 (rank : 177)	θ value	8.36355e-22 (rank : 223)
Query Neighborhood Hits	2923	Target Neighborhood Hits	875	Shared Neighborhood Hits	784
SwissProt Accessions	Q60823	Gene names	Akt2
Domain Architecture
Description	RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta).

SGK2_MOUSE
NC score	0.720891 (rank : 178)	θ value	3.51386e-20 (rank : 264)
Query Neighborhood Hits	2923	Target Neighborhood Hits	833	Shared Neighborhood Hits	784
SwissProt Accessions	Q9QZS5, Q8R0P6	Gene names	Sgk2
Domain Architecture
Description	Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 2).

SGK1_HUMAN
NC score	0.720859 (rank : 179)	θ value	1.86321e-21 (rank : 235)
Query Neighborhood Hits	2923	Target Neighborhood Hits	848	Shared Neighborhood Hits	786
SwissProt Accessions	O00141, Q5TCN3, Q9UN56	Gene names	SGK, SGK1
Domain Architecture
Description	Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 1).

SGK2_HUMAN
NC score	0.720856 (rank : 180)	θ value	5.42112e-21 (rank : 244)
Query Neighborhood Hits	2923	Target Neighborhood Hits	840	Shared Neighborhood Hits	788
SwissProt Accessions	Q9HBY8, Q9UKG6	Gene names	SGK2
Domain Architecture
Description	Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 2).

PAK4_HUMAN
NC score	0.720797 (rank : 181)	θ value	8.65492e-19 (rank : 299)
Query Neighborhood Hits	2923	Target Neighborhood Hits	924	Shared Neighborhood Hits	829
SwissProt Accessions	O96013, Q8N4E1, Q8NCH5, Q8NDE3, Q9BU33, Q9ULS8	Gene names	PAK4, KIAA1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

SGK1_MOUSE
NC score	0.720682 (rank : 182)	θ value	2.06002e-20 (rank : 259)
Query Neighborhood Hits	2923	Target Neighborhood Hits	848	Shared Neighborhood Hits	786
SwissProt Accessions	Q9WVC6	Gene names	Sgk, Sgk1
Domain Architecture
Description	Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 1).

ST32C_MOUSE
NC score	0.720383 (rank : 183)	θ value	5.25075e-16 (rank : 381)
Query Neighborhood Hits	2923	Target Neighborhood Hits	824	Shared Neighborhood Hits	779
SwissProt Accessions	Q8QZV4, Q9JJG4	Gene names	Stk32c, Pkek
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 32C (EC 2.7.11.1).

IKKA_MOUSE
NC score	0.720042 (rank : 184)	θ value	1.99529e-15 (rank : 398)
Query Neighborhood Hits	2923	Target Neighborhood Hits	867	Shared Neighborhood Hits	805
SwissProt Accessions	Q60680, Q80VU2, Q9D2X3	Gene names	Chuk, Ikka
Domain Architecture
Description	Inhibitor of nuclear factor kappa-B kinase alpha subunit (EC 2.7.11.10) (I kappa-B kinase alpha) (IkBKA) (IKK-alpha) (IKK-A) (IkappaB kinase) (I-kappa-B kinase 1) (IKK1) (Conserved helix-loop- helix ubiquitous kinase) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA).

ST32A_MOUSE
NC score	0.719958 (rank : 185)	θ value	6.41864e-14 (rank : 461)
Query Neighborhood Hits	2923	Target Neighborhood Hits	833	Shared Neighborhood Hits	784
SwissProt Accessions	Q8BGW6, Q7TPQ4	Gene names	Stk32a
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 32A (EC 2.7.11.1).

AKT1_HUMAN
NC score	0.719466 (rank : 186)	θ value	1.5242e-23 (rank : 198)
Query Neighborhood Hits	2923	Target Neighborhood Hits	885	Shared Neighborhood Hits	789
SwissProt Accessions	P31749, Q9BWB6	Gene names	AKT1, PKB, RAC
Domain Architecture
Description	RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-alpha) (Protein kinase B) (PKB) (C-AKT).

IKKB_MOUSE
NC score	0.719435 (rank : 187)	θ value	8.95645e-16 (rank : 388)
Query Neighborhood Hits	2923	Target Neighborhood Hits	984	Shared Neighborhood Hits	864
SwissProt Accessions	O88351, Q9R1J6	Gene names	Ikbkb, Ikkb
Domain Architecture
Description	Inhibitor of nuclear factor kappa B kinase subunit beta (EC 2.7.11.10) (I-kappa-B-kinase beta) (IkBKB) (IKK-beta) (IKK-B) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB).

PAK4_MOUSE
NC score	0.719206 (rank : 188)	θ value	8.65492e-19 (rank : 300)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1098	Shared Neighborhood Hits	866
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

PAK7_MOUSE
NC score	0.719071 (rank : 189)	θ value	7.0802e-21 (rank : 247)
Query Neighborhood Hits	2923	Target Neighborhood Hits	875	Shared Neighborhood Hits	793
SwissProt Accessions	Q8C015, Q3TQJ7, Q6RWS7	Gene names	Pak7, Pak5
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PAK 7 (EC 2.7.11.1) (p21-activated kinase 7) (PAK-7) (p21-activated kinase 5).

AKT1_MOUSE
NC score	0.718919 (rank : 190)	θ value	7.56453e-23 (rank : 206)
Query Neighborhood Hits	2923	Target Neighborhood Hits	878	Shared Neighborhood Hits	788
SwissProt Accessions	P31750, Q62274	Gene names	Akt1, Akt, Rac
Domain Architecture
Description	RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-alpha) (AKT1 kinase) (Protein kinase B) (PKB) (C-AKT) (Thymoma viral proto- oncogene).

ST32A_HUMAN
NC score	0.718914 (rank : 191)	θ value	1.42992e-13 (rank : 479)
Query Neighborhood Hits	2923	Target Neighborhood Hits	834	Shared Neighborhood Hits	780
SwissProt Accessions	Q8WU08	Gene names	STK32A
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 32A (EC 2.7.11.1) (YANK1).

NEK2_HUMAN
NC score	0.718835 (rank : 192)	θ value	1.42992e-13 (rank : 478)
Query Neighborhood Hits	2923	Target Neighborhood Hits	908	Shared Neighborhood Hits	818
SwissProt Accessions	P51955, Q53FD6, Q5VXZ1, Q6NZX8, Q7Z634, Q86XH2, Q96QN9	Gene names	NEK2, NLK1
Domain Architecture
Description	Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (NimA-related protein kinase 2) (NimA-like protein kinase 1) (HSPK 21).

PAK7_HUMAN
NC score	0.718795 (rank : 193)	θ value	9.24701e-21 (rank : 249)
Query Neighborhood Hits	2923	Target Neighborhood Hits	875	Shared Neighborhood Hits	792
SwissProt Accessions	Q9P286, Q5W115, Q9BX09, Q9ULF6	Gene names	PAK7, KIAA1264, PAK5
Domain Architecture
Description	Serine/threonine-protein kinase PAK 7 (EC 2.7.11.1) (p21-activated kinase 7) (PAK-7) (PAK-5).

IKKB_HUMAN
NC score	0.718742 (rank : 194)	θ value	6.85773e-16 (rank : 385)
Query Neighborhood Hits	2923	Target Neighborhood Hits	980	Shared Neighborhood Hits	863
SwissProt Accessions	O14920, O75327	Gene names	IKBKB, IKKB
Domain Architecture
Description	Inhibitor of nuclear factor kappa B kinase subunit beta (EC 2.7.11.10) (I-kappa-B-kinase beta) (IkBKB) (IKK-beta) (IKK-B) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB).

ST32C_HUMAN
NC score	0.718647 (rank : 195)	θ value	4.02038e-16 (rank : 377)
Query Neighborhood Hits	2923	Target Neighborhood Hits	832	Shared Neighborhood Hits	778
SwissProt Accessions	Q86UX6, Q5T0Q5, Q86UE1	Gene names	STK32C
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 32C (EC 2.7.11.1) (PKE) (YANK3).

ST32B_MOUSE
NC score	0.718571 (rank : 196)	θ value	6.20254e-17 (rank : 352)
Query Neighborhood Hits	2923	Target Neighborhood Hits	828	Shared Neighborhood Hits	779
SwissProt Accessions	Q9JJX8, Q7TMD3, Q8C4E0	Gene names	Stk32b, Stk32
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 32B (EC 2.7.11.1).

PIM1_HUMAN
NC score	0.718402 (rank : 197)	θ value	8.38298e-14 (rank : 470)
Query Neighborhood Hits	2923	Target Neighborhood Hits	797	Shared Neighborhood Hits	758
SwissProt Accessions	P11309, Q38RT9, Q96RG3	Gene names	PIM1
Domain Architecture
Description	Proto-oncogene serine/threonine-protein kinase Pim-1 (EC 2.7.11.1).

PAK2_HUMAN
NC score	0.718346 (rank : 198)	θ value	1.42661e-21 (rank : 231)
Query Neighborhood Hits	2923	Target Neighborhood Hits	862	Shared Neighborhood Hits	802
SwissProt Accessions	Q13177, Q13154	Gene names	PAK2
Domain Architecture
Description	Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (p21-activated kinase 2) (PAK-2) (PAK65) (Gamma-PAK) (S6/H4 kinase).

IKKA_HUMAN
NC score	0.718122 (rank : 199)	θ value	9.90251e-15 (rank : 424)
Query Neighborhood Hits	2923	Target Neighborhood Hits	863	Shared Neighborhood Hits	798
SwissProt Accessions	O15111, O14666, Q13132, Q92467	Gene names	CHUK, IKKA
Domain Architecture
Description	Inhibitor of nuclear factor kappa-B kinase alpha subunit (EC 2.7.11.10) (I kappa-B kinase alpha) (IkBKA) (IKK-alpha) (IKK-A) (IkappaB kinase) (I-kappa-B kinase 1) (IKK1) (Conserved helix-loop- helix ubiquitous kinase) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA).

PAK2_MOUSE
NC score	0.718021 (rank : 200)	θ value	8.36355e-22 (rank : 225)
Query Neighborhood Hits	2923	Target Neighborhood Hits	858	Shared Neighborhood Hits	797
SwissProt Accessions	Q8CIN4	Gene names	Pak2
Domain Architecture
Description	Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (p21-activated kinase 2) (PAK-2).

ST32B_HUMAN
NC score	0.717938 (rank : 201)	θ value	5.8054e-15 (rank : 416)
Query Neighborhood Hits	2923	Target Neighborhood Hits	830	Shared Neighborhood Hits	779
SwissProt Accessions	Q9NY57, Q6UXH3, Q8IY14	Gene names	STK32B
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 32B (EC 2.7.11.1) (YANK2).

NEK4_MOUSE
NC score	0.717770 (rank : 202)	θ value	3.28887e-18 (rank : 319)
Query Neighborhood Hits	2923	Target Neighborhood Hits	899	Shared Neighborhood Hits	808
SwissProt Accessions	Q9Z1J2, O35673, Q9R1J1	Gene names	Nek4, Stk2
Domain Architecture
Description	Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2).

NEK2_MOUSE
NC score	0.717670 (rank : 203)	θ value	3.52202e-12 (rank : 541)
Query Neighborhood Hits	2923	Target Neighborhood Hits	876	Shared Neighborhood Hits	788
SwissProt Accessions	O35942, O35959	Gene names	Nek2
Domain Architecture
Description	Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (NimA-related protein kinase 2).

PKN3_HUMAN
NC score	0.716943 (rank : 204)	θ value	4.15078e-21 (rank : 243)
Query Neighborhood Hits	2923	Target Neighborhood Hits	893	Shared Neighborhood Hits	811
SwissProt Accessions	Q6P5Z2, Q9UM03	Gene names	PKN3, PKNBETA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

PIM1_MOUSE
NC score	0.716860 (rank : 205)	θ value	1.2105e-12 (rank : 509)
Query Neighborhood Hits	2923	Target Neighborhood Hits	787	Shared Neighborhood Hits	749
SwissProt Accessions	P06803	Gene names	Pim1, Pim-1
Domain Architecture	No domain graphic available
Description	Proto-oncogene serine/threonine-protein kinase Pim-1 (EC 2.7.11.1).

NEK4_HUMAN
NC score	0.716817 (rank : 206)	θ value	1.24977e-17 (rank : 340)
Query Neighborhood Hits	2923	Target Neighborhood Hits	883	Shared Neighborhood Hits	801
SwissProt Accessions	P51957	Gene names	NEK4, STK2
Domain Architecture
Description	Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2) (Serine/threonine-protein kinase NRK2).

SGK3_HUMAN
NC score	0.716430 (rank : 207)	θ value	3.51386e-20 (rank : 265)
Query Neighborhood Hits	2923	Target Neighborhood Hits	877	Shared Neighborhood Hits	783
SwissProt Accessions	Q96BR1, Q9P1Q7, Q9UKG5	Gene names	SGK3, SGKL
Domain Architecture
Description	Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid- regulated kinase-like).

GRK5_MOUSE
NC score	0.716285 (rank : 208)	θ value	8.65492e-19 (rank : 297)
Query Neighborhood Hits	2923	Target Neighborhood Hits	823	Shared Neighborhood Hits	769
SwissProt Accessions	Q8VEB1, O70292, O70297	Gene names	Grk5, Gprk5
Domain Architecture
Description	G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK5).

GRK6_HUMAN
NC score	0.716050 (rank : 209)	θ value	8.65492e-19 (rank : 298)
Query Neighborhood Hits	2923	Target Neighborhood Hits	823	Shared Neighborhood Hits	775
SwissProt Accessions	P43250, O60541, Q13652	Gene names	GRK6, GPRK6
Domain Architecture
Description	G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK6).

KGP2_MOUSE
NC score	0.715972 (rank : 210)	θ value	5.43371e-13 (rank : 498)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1029	Shared Neighborhood Hits	883
SwissProt Accessions	Q61410	Gene names	Prkg2, Prkgr2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

KGP2_HUMAN
NC score	0.715962 (rank : 211)	θ value	2.43908e-13 (rank : 488)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1023	Shared Neighborhood Hits	871
SwissProt Accessions	Q13237, O00125, O60916	Gene names	PRKG2, PRKGR2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

SGK3_MOUSE
NC score	0.715927 (rank : 212)	θ value	5.99374e-20 (rank : 273)
Query Neighborhood Hits	2923	Target Neighborhood Hits	882	Shared Neighborhood Hits	783
SwissProt Accessions	Q9ERE3, Q3UAY2	Gene names	Sgk3, Cisk, Sgkl
Domain Architecture
Description	Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid- regulated kinase-like) (Cytokine-independent survival kinase).

PAK1_HUMAN
NC score	0.715909 (rank : 213)	θ value	1.5773e-20 (rank : 252)
Query Neighborhood Hits	2923	Target Neighborhood Hits	873	Shared Neighborhood Hits	802
SwissProt Accessions	Q13153, O75561, Q13567, Q32M53, Q32M54, Q86W79	Gene names	PAK1
Domain Architecture
Description	Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (p21-activated kinase 1) (PAK-1) (P65-PAK) (Alpha-PAK).

GRK5_HUMAN
NC score	0.715859 (rank : 214)	θ value	1.92812e-18 (rank : 305)
Query Neighborhood Hits	2923	Target Neighborhood Hits	819	Shared Neighborhood Hits	769
SwissProt Accessions	P34947	Gene names	GRK5, GPRK5
Domain Architecture
Description	G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK5).

PKN2_MOUSE
NC score	0.715806 (rank : 215)	θ value	4.01107e-24 (rank : 190)
Query Neighborhood Hits	2923	Target Neighborhood Hits	899	Shared Neighborhood Hits	818
SwissProt Accessions	Q8BWW9, Q80WS2, Q8BJL7	Gene names	Pkn2, Prkcl2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein kinase C- like 2) (Protein-kinase C-related kinase 2).

PAK3_MOUSE
NC score	0.715716 (rank : 216)	θ value	4.15078e-21 (rank : 242)
Query Neighborhood Hits	2923	Target Neighborhood Hits	874	Shared Neighborhood Hits	795
SwissProt Accessions	Q61036, O88645, Q8K1R5, Q8K1R6	Gene names	Pak3, Pak-3, Pakb, Stk4
Domain Architecture
Description	Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (p21-activated kinase 3) (PAK-3) (Beta-PAK) (CDC42/RAC effector kinase PAK-B).

PAK3_HUMAN
NC score	0.715595 (rank : 217)	θ value	3.51386e-20 (rank : 262)
Query Neighborhood Hits	2923	Target Neighborhood Hits	887	Shared Neighborhood Hits	810
SwissProt Accessions	O75914, Q5JWX1, Q5JWX2, Q7Z2D6, Q7Z2E4, Q7Z3Z8, Q8WWK5, Q8WX23, Q9P0J8	Gene names	PAK3, OPHN3
Domain Architecture
Description	Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (p21-activated kinase 3) (PAK-3) (Beta-PAK) (Oligophrenin-3).

PKN2_HUMAN
NC score	0.715528 (rank : 218)	θ value	3.07116e-24 (rank : 187)
Query Neighborhood Hits	2923	Target Neighborhood Hits	892	Shared Neighborhood Hits	814
SwissProt Accessions	Q16513, Q9H1W4	Gene names	PKN2, PRK2, PRKCL2
Domain Architecture
Description	Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein kinase C- like 2) (Protein-kinase C-related kinase 2).

PIM3_HUMAN
NC score	0.715515 (rank : 219)	θ value	6.64225e-11 (rank : 607)
Query Neighborhood Hits	2923	Target Neighborhood Hits	789	Shared Neighborhood Hits	751
SwissProt Accessions	Q86V86, Q68BM2	Gene names	PIM3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase Pim-3 (EC 2.7.11.1).

PKN3_MOUSE
NC score	0.715442 (rank : 220)	θ value	2.27762e-19 (rank : 285)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1009	Shared Neighborhood Hits	849
SwissProt Accessions	Q8K045	Gene names	Pkn3, Pknbeta
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

GRK6_MOUSE
NC score	0.715293 (rank : 221)	θ value	4.29542e-18 (rank : 323)
Query Neighborhood Hits	2923	Target Neighborhood Hits	820	Shared Neighborhood Hits	773
SwissProt Accessions	O70293, O70294, O70295	Gene names	Grk6, Gprk6
Domain Architecture
Description	G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK6).

PAK1_MOUSE
NC score	0.715246 (rank : 222)	θ value	1.74391e-19 (rank : 280)
Query Neighborhood Hits	2923	Target Neighborhood Hits	878	Shared Neighborhood Hits	805
SwissProt Accessions	O88643	Gene names	Pak1, Paka
Domain Architecture
Description	Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (p21-activated kinase 1) (PAK-1) (P65-PAK) (Alpha-PAK) (CDC42/RAC effector kinase PAK-A).

NEK11_MOUSE
NC score	0.715223 (rank : 223)	θ value	9.56915e-18 (rank : 337)
Query Neighborhood Hits	2923	Target Neighborhood Hits	875	Shared Neighborhood Hits	798
SwissProt Accessions	Q8C0Q4, Q8BLS6, Q8BW62	Gene names	Nek11
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11).

NEK6_HUMAN
NC score	0.714784 (rank : 224)	θ value	6.41864e-14 (rank : 459)
Query Neighborhood Hits	2923	Target Neighborhood Hits	848	Shared Neighborhood Hits	791
SwissProt Accessions	Q9HC98, Q96E83, Q9ULX2	Gene names	NEK6
Domain Architecture
Description	Serine/threonine-protein kinase Nek6 (EC 2.7.11.1) (NimA-related protein kinase 6) (Protein kinase SID6-1512).

NEK6_MOUSE
NC score	0.714710 (rank : 225)	θ value	8.38298e-14 (rank : 467)
Query Neighborhood Hits	2923	Target Neighborhood Hits	851	Shared Neighborhood Hits	791
SwissProt Accessions	Q9ES70, Q3TCE9, Q8C6E6, Q9D0E2, Q9DBI8	Gene names	Nek6
Domain Architecture
Description	Serine/threonine-protein kinase Nek6 (EC 2.7.11.1) (NimA-related protein kinase 6).

RK_MOUSE
NC score	0.714099 (rank : 226)	θ value	3.07829e-16 (rank : 375)
Query Neighborhood Hits	2923	Target Neighborhood Hits	829	Shared Neighborhood Hits	777
SwissProt Accessions	Q9WVL4	Gene names	Grk1, Rhok
Domain Architecture
Description	Rhodopsin kinase precursor (EC 2.7.11.14) (RK) (G protein-coupled receptor kinase 1).

PKN1_MOUSE
NC score	0.714080 (rank : 227)	θ value	8.36355e-22 (rank : 226)
Query Neighborhood Hits	2923	Target Neighborhood Hits	888	Shared Neighborhood Hits	801
SwissProt Accessions	P70268, Q7TST2	Gene names	Pkn1, Pkn, Prk1, Prkcl1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protein kinase C- like 1) (Protein-kinase C-related kinase 1) (Protein kinase C-like PKN) (Serine-threonine protein kinase N).

CDKL3_MOUSE
NC score	0.714030 (rank : 228)	θ value	2.27762e-19 (rank : 283)
Query Neighborhood Hits	2923	Target Neighborhood Hits	857	Shared Neighborhood Hits	788
SwissProt Accessions	Q8BLF2, Q5M6W2, Q8BKR2, Q8BL49, Q8BVE0, Q8K134	Gene names	Cdkl3
Domain Architecture	No domain graphic available
Description	Cyclin-dependent kinase-like 3 (EC 2.7.11.22).

PIM3_MOUSE
NC score	0.713910 (rank : 229)	θ value	2.98157e-11 (rank : 588)
Query Neighborhood Hits	2923	Target Neighborhood Hits	783	Shared Neighborhood Hits	747
SwissProt Accessions	P58750	Gene names	Pim3
Domain Architecture
Description	Serine/threonine-protein kinase Pim-3 (EC 2.7.11.1).

KGP1A_HUMAN
NC score	0.713778 (rank : 230)	θ value	8.95645e-16 (rank : 389)
Query Neighborhood Hits	2923	Target Neighborhood Hits	901	Shared Neighborhood Hits	798
SwissProt Accessions	Q13976	Gene names	PRKG1, PRKGR1A
Domain Architecture
Description	cGMP-dependent protein kinase 1, alpha isozyme (EC 2.7.11.12) (CGK 1 alpha) (cGKI-alpha).

KGP1B_MOUSE
NC score	0.713673 (rank : 231)	θ value	8.95645e-16 (rank : 391)
Query Neighborhood Hits	2923	Target Neighborhood Hits	922	Shared Neighborhood Hits	815
SwissProt Accessions	Q9Z0Z0	Gene names	Prkg1, Prkg1b, Prkgr1b
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KGP1B_HUMAN
NC score	0.713609 (rank : 232)	θ value	8.95645e-16 (rank : 390)
Query Neighborhood Hits	2923	Target Neighborhood Hits	921	Shared Neighborhood Hits	815
SwissProt Accessions	P14619	Gene names	PRKG1, PRKG1B, PRKGR1B
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

NEK11_HUMAN
NC score	0.713498 (rank : 233)	θ value	8.10077e-17 (rank : 353)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1043	Shared Neighborhood Hits	888
SwissProt Accessions	Q8NG66, Q5JPC0, Q8NG65, Q8TBY1, Q9H5F4	Gene names	NEK11
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11).

PKN1_HUMAN
NC score	0.713483 (rank : 234)	θ value	2.20094e-22 (rank : 212)
Query Neighborhood Hits	2923	Target Neighborhood Hits	886	Shared Neighborhood Hits	805
SwissProt Accessions	Q16512, Q15143, Q8IUV5	Gene names	PKN1, PKN, PRK1, PRKCL1
Domain Architecture
Description	Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protein kinase C- like 1) (Protein-kinase C-related kinase 1) (Protein kinase C-like PKN) (Serine-threonine protein kinase N) (Protein kinase PKN-alpha).

CDKL3_HUMAN
NC score	0.713429 (rank : 235)	θ value	6.62687e-19 (rank : 296)
Query Neighborhood Hits	2923	Target Neighborhood Hits	853	Shared Neighborhood Hits	790
SwissProt Accessions	Q8IVW4, Q9P114	Gene names	CDKL3, NKIAMRE
Domain Architecture	No domain graphic available
Description	Cyclin-dependent kinase-like 3 (EC 2.7.11.22) (Serine/threonine protein kinase NKIAMRE).

CDKL5_HUMAN
NC score	0.713280 (rank : 236)	θ value	6.85773e-16 (rank : 383)
Query Neighborhood Hits	2923	Target Neighborhood Hits	967	Shared Neighborhood Hits	831
SwissProt Accessions	O76039, Q14198, Q5H985, Q9UJL6	Gene names	CDKL5, STK9
Domain Architecture
Description	Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine- protein kinase 9).

GRK4_HUMAN
NC score	0.712897 (rank : 237)	θ value	2.5182e-18 (rank : 311)
Query Neighborhood Hits	2923	Target Neighborhood Hits	822	Shared Neighborhood Hits	775
SwissProt Accessions	P32298, O00641, O00642, Q13293, Q13294, Q13295, Q14453, Q14725, Q15313, Q15314, Q15315, Q15316	Gene names	GRK4, GPRK2L, GPRK4
Domain Architecture
Description	G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK4) (ITI1).

GRK4_MOUSE
NC score	0.712535 (rank : 238)	θ value	5.60996e-18 (rank : 325)
Query Neighborhood Hits	2923	Target Neighborhood Hits	808	Shared Neighborhood Hits	765
SwissProt Accessions	O70291	Gene names	Grk4, Gprk2l
Domain Architecture
Description	G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK4).

M3K1_MOUSE
NC score	0.712378 (rank : 239)	θ value	1.25267e-09 (rank : 670)
Query Neighborhood Hits	2923	Target Neighborhood Hits	952	Shared Neighborhood Hits	820
SwissProt Accessions	P53349, Q60831, Q9R0U3, Q9R256	Gene names	Map3k1, Mekk, Mekk1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1).

KPCT_MOUSE
NC score	0.712053 (rank : 240)	θ value	1.5773e-20 (rank : 251)
Query Neighborhood Hits	2923	Target Neighborhood Hits	895	Shared Neighborhood Hits	785
SwissProt Accessions	Q02111	Gene names	Prkcq, Pkcq
Domain Architecture
Description	Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta).

KPCT_HUMAN
NC score	0.712028 (rank : 241)	θ value	2.27762e-19 (rank : 284)
Query Neighborhood Hits	2923	Target Neighborhood Hits	897	Shared Neighborhood Hits	787
SwissProt Accessions	Q04759, Q3MJF1, Q64FY5, Q9H508, Q9H549	Gene names	PRKCQ, PRKCT
Domain Architecture
Description	Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta).

TTK_HUMAN
NC score	0.711888 (rank : 242)	θ value	7.09661e-13 (rank : 501)
Query Neighborhood Hits	2923	Target Neighborhood Hits	816	Shared Neighborhood Hits	749
SwissProt Accessions	P33981	Gene names	TTK, MPS1L1
Domain Architecture
Description	Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein kinase) (PYT).

CSKP_MOUSE
NC score	0.711306 (rank : 243)	θ value	8.61488e-35 (rank : 86)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1027	Shared Neighborhood Hits	807
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

TBK1_MOUSE
NC score	0.711129 (rank : 244)	θ value	6.64225e-11 (rank : 609)
Query Neighborhood Hits	2923	Target Neighborhood Hits	893	Shared Neighborhood Hits	825
SwissProt Accessions	Q9WUN2, Q9CT90, Q9DC03	Gene names	Tbk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (TANK-binding kinase 1) (T2K).

RK_HUMAN
NC score	0.711115 (rank : 245)	θ value	2.88119e-14 (rank : 442)
Query Neighborhood Hits	2923	Target Neighborhood Hits	835	Shared Neighborhood Hits	777
SwissProt Accessions	Q15835	Gene names	GRK1, RHOK
Domain Architecture
Description	Rhodopsin kinase precursor (EC 2.7.11.14) (RK) (G protein-coupled receptor kinase 1).

NEK7_MOUSE
NC score	0.710900 (rank : 246)	θ value	1.86753e-13 (rank : 483)
Query Neighborhood Hits	2923	Target Neighborhood Hits	847	Shared Neighborhood Hits	791
SwissProt Accessions	Q9ES74, Q3UEV7	Gene names	Nek7
Domain Architecture
Description	Serine/threonine-protein kinase Nek7 (EC 2.7.11.1) (NimA-related protein kinase 7).

NEK7_HUMAN
NC score	0.710855 (rank : 247)	θ value	1.09485e-13 (rank : 477)
Query Neighborhood Hits	2923	Target Neighborhood Hits	846	Shared Neighborhood Hits	790
SwissProt Accessions	Q8TDX7	Gene names	NEK7
Domain Architecture
Description	Serine/threonine-protein kinase Nek7 (EC 2.7.11.1) (NimA-related protein kinase 7).

MAST3_HUMAN
NC score	0.710842 (rank : 248)	θ value	6.41864e-14 (rank : 456)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1128	Shared Neighborhood Hits	890
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

KPCL_MOUSE
NC score	0.710841 (rank : 249)	θ value	1.92812e-18 (rank : 307)
Query Neighborhood Hits	2923	Target Neighborhood Hits	891	Shared Neighborhood Hits	779
SwissProt Accessions	P23298	Gene names	Prkch, Pkch
Domain Architecture
Description	Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta) (PKC-L).

TTK_MOUSE
NC score	0.710833 (rank : 250)	θ value	6.41864e-14 (rank : 462)
Query Neighborhood Hits	2923	Target Neighborhood Hits	803	Shared Neighborhood Hits	735
SwissProt Accessions	P35761	Gene names	Ttk, Esk
Domain Architecture
Description	Dual specificity protein kinase TTK (EC 2.7.12.1) (ESK) (PYT).

NEK8_HUMAN
NC score	0.710705 (rank : 251)	θ value	1.33526e-19 (rank : 277)
Query Neighborhood Hits	2923	Target Neighborhood Hits	872	Shared Neighborhood Hits	795
SwissProt Accessions	Q86SG6, Q2M1S6, Q8NDH1	Gene names	NEK8, JCK, NEK12A
Domain Architecture
Description	Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never in mitosis A-related kinase 8) (NimA-related protein kinase 8) (NIMA-related kinase 12a).

NEK8_MOUSE
NC score	0.710680 (rank : 252)	θ value	7.82807e-20 (rank : 276)
Query Neighborhood Hits	2923	Target Neighborhood Hits	872	Shared Neighborhood Hits	793
SwissProt Accessions	Q91ZR4, Q3U498, Q9D685	Gene names	Nek8, Jck
Domain Architecture
Description	Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never in mitosis A-related kinase 8) (NimA-related protein kinase 8).

CDKL1_MOUSE
NC score	0.710595 (rank : 253)	θ value	7.32683e-18 (rank : 332)
Query Neighborhood Hits	2923	Target Neighborhood Hits	829	Shared Neighborhood Hits	776
SwissProt Accessions	Q8CEQ0	Gene names	Cdkl1
Domain Architecture	No domain graphic available
Description	Cyclin-dependent kinase-like 1 (EC 2.7.11.22).

TBK1_HUMAN
NC score	0.710547 (rank : 254)	θ value	1.9326e-10 (rank : 637)
Query Neighborhood Hits	2923	Target Neighborhood Hits	861	Shared Neighborhood Hits	799
SwissProt Accessions	Q9UHD2, Q8IYV3, Q9NUJ5	Gene names	TBK1, NAK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (TANK-binding kinase 1) (T2K) (NF-kappa-B-activating kinase).

CDKL1_HUMAN
NC score	0.710447 (rank : 255)	θ value	3.63628e-17 (rank : 348)
Query Neighborhood Hits	2923	Target Neighborhood Hits	830	Shared Neighborhood Hits	776
SwissProt Accessions	Q00532, Q6QUA0	Gene names	CDKL1
Domain Architecture
Description	Cyclin-dependent kinase-like 1 (EC 2.7.11.22) (Serine/threonine- protein kinase KKIALRE) (Protein kinase p42 KKIALRE).

M3K3_MOUSE
NC score	0.710362 (rank : 256)	θ value	4.91457e-14 (rank : 449)
Query Neighborhood Hits	2923	Target Neighborhood Hits	876	Shared Neighborhood Hits	799
SwissProt Accessions	Q61084	Gene names	Map3k3, Mekk3
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3).

M3K4_HUMAN
NC score	0.710245 (rank : 257)	θ value	7.32683e-18 (rank : 334)
Query Neighborhood Hits	2923	Target Neighborhood Hits	911	Shared Neighborhood Hits	817
SwissProt Accessions	Q9Y6R4, Q92612	Gene names	MAP3K4, KIAA0213, MAPKKK4, MEKK4, MTK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4) (MAP three kinase 1).

KPCD_HUMAN
NC score	0.710063 (rank : 258)	θ value	1.24977e-17 (rank : 338)
Query Neighborhood Hits	2923	Target Neighborhood Hits	900	Shared Neighborhood Hits	785
SwissProt Accessions	Q05655, Q15144	Gene names	PRKCD
Domain Architecture
Description	Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta).

KPCD_MOUSE
NC score	0.710057 (rank : 259)	θ value	1.92812e-18 (rank : 306)
Query Neighborhood Hits	2923	Target Neighborhood Hits	888	Shared Neighborhood Hits	783
SwissProt Accessions	P28867, Q91V85, Q9Z333	Gene names	Prkcd, Pkcd
Domain Architecture
Description	Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta).

KPCI_MOUSE
NC score	0.709994 (rank : 260)	θ value	3.07829e-16 (rank : 372)
Query Neighborhood Hits	2923	Target Neighborhood Hits	888	Shared Neighborhood Hits	793
SwissProt Accessions	Q62074	Gene names	Prkci, Pkcl
Domain Architecture
Description	Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota) (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota).

M3K3_HUMAN
NC score	0.709983 (rank : 261)	θ value	4.91457e-14 (rank : 448)
Query Neighborhood Hits	2923	Target Neighborhood Hits	885	Shared Neighborhood Hits	808
SwissProt Accessions	Q99759	Gene names	MAP3K3, MAPKKK3, MEKK3
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3).

KPCI_HUMAN
NC score	0.709871 (rank : 262)	θ value	5.25075e-16 (rank : 380)
Query Neighborhood Hits	2923	Target Neighborhood Hits	885	Shared Neighborhood Hits	793
SwissProt Accessions	P41743, Q8WW06	Gene names	PRKCI, DXS1179E
Domain Architecture
Description	Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota) (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) (PRKC-lambda/iota).

IKKE_HUMAN
NC score	0.709514 (rank : 263)	θ value	2.98157e-11 (rank : 582)
Query Neighborhood Hits	2923	Target Neighborhood Hits	837	Shared Neighborhood Hits	778
SwissProt Accessions	Q14164	Gene names	IKBKE, IKKE, IKKI, KIAA0151
Domain Architecture
Description	Inhibitor of nuclear factor kappa-B kinase epsilon subunit (EC 2.7.11.10) (I kappa-B kinase epsilon) (IkBKE) (IKK-epsilon) (IKK- E) (Inducible I kappa-B kinase) (IKK-i).

KPCL_HUMAN
NC score	0.709487 (rank : 264)	θ value	9.56915e-18 (rank : 336)
Query Neighborhood Hits	2923	Target Neighborhood Hits	887	Shared Neighborhood Hits	778
SwissProt Accessions	P24723, Q16246	Gene names	PRKCH, PKCL
Domain Architecture
Description	Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta) (PKC-L).

CSKP_HUMAN
NC score	0.709405 (rank : 265)	θ value	8.61488e-35 (rank : 85)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1022	Shared Neighborhood Hits	808
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

M3K6_HUMAN
NC score	0.709128 (rank : 266)	θ value	1.02475e-11 (rank : 568)
Query Neighborhood Hits	2923	Target Neighborhood Hits	889	Shared Neighborhood Hits	811
SwissProt Accessions	O95382	Gene names	MAP3K6, MAPKKK6
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 6 (EC 2.7.11.25).

M3K2_MOUSE
NC score	0.709072 (rank : 267)	θ value	1.02475e-11 (rank : 567)
Query Neighborhood Hits	2923	Target Neighborhood Hits	846	Shared Neighborhood Hits	786
SwissProt Accessions	Q61083	Gene names	Map3k2, Mekk2
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2).

KPCE_MOUSE
NC score	0.708870 (rank : 268)	θ value	5.99374e-20 (rank : 270)
Query Neighborhood Hits	2923	Target Neighborhood Hits	906	Shared Neighborhood Hits	787
SwissProt Accessions	P16054	Gene names	Prkce, Pkce, Pkcea
Domain Architecture
Description	Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon).

KPCE_HUMAN
NC score	0.708852 (rank : 269)	θ value	2.97466e-19 (rank : 286)
Query Neighborhood Hits	2923	Target Neighborhood Hits	906	Shared Neighborhood Hits	790
SwissProt Accessions	Q02156, Q53SL4, Q53SM5, Q9UE81	Gene names	PRKCE, PKCE
Domain Architecture
Description	Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon).

MAST2_MOUSE
NC score	0.708850 (rank : 270)	θ value	1.68911e-14 (rank : 433)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1110	Shared Neighborhood Hits	865
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

CDKL2_HUMAN
NC score	0.708724 (rank : 271)	θ value	1.47631e-18 (rank : 302)
Query Neighborhood Hits	2923	Target Neighborhood Hits	838	Shared Neighborhood Hits	782
SwissProt Accessions	Q92772	Gene names	CDKL2
Domain Architecture	No domain graphic available
Description	Cyclin-dependent kinase-like 2 (EC 2.7.11.22) (Serine/threonine- protein kinase KKIAMRE) (Protein kinase p56 KKIAMRE).

CDKL4_MOUSE
NC score	0.708639 (rank : 272)	θ value	5.07402e-19 (rank : 293)
Query Neighborhood Hits	2923	Target Neighborhood Hits	833	Shared Neighborhood Hits	779
SwissProt Accessions	Q3TZA2	Gene names	Cdkl4
Domain Architecture	No domain graphic available
Description	Cyclin-dependent kinase-like 4 (EC 2.7.11.22).

CDKL2_MOUSE
NC score	0.708519 (rank : 273)	θ value	4.58923e-20 (rank : 266)
Query Neighborhood Hits	2923	Target Neighborhood Hits	854	Shared Neighborhood Hits	785
SwissProt Accessions	Q9QUK0, Q3UL60, Q3V3X7, Q9QYI1, Q9QYI2	Gene names	Cdkl2, Kkiamre, Kkm
Domain Architecture	No domain graphic available
Description	Cyclin-dependent kinase-like 2 (EC 2.7.11.22) (Serine/threonine- protein kinase KKIAMRE).

M3K4_MOUSE
NC score	0.708472 (rank : 274)	θ value	3.63628e-17 (rank : 349)
Query Neighborhood Hits	2923	Target Neighborhood Hits	924	Shared Neighborhood Hits	817
SwissProt Accessions	O08648, O08649, O70124	Gene names	Map3k4, Mekk4
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4).

IKKE_MOUSE
NC score	0.708345 (rank : 275)	θ value	3.29651e-10 (rank : 640)
Query Neighborhood Hits	2923	Target Neighborhood Hits	848	Shared Neighborhood Hits	785
SwissProt Accessions	Q9R0T8	Gene names	Ikbke, Ikke, Ikki
Domain Architecture
Description	Inhibitor of nuclear factor kappa-B kinase epsilon subunit (EC 2.7.11.10) (I kappa-B kinase epsilon) (IkBKE) (IKK-epsilon) (IKK- E) (Inducible I kappa-B kinase) (IKK-i).

MKNK1_HUMAN
NC score	0.708227 (rank : 276)	θ value	1.80048e-24 (rank : 183)
Query Neighborhood Hits	2923	Target Neighborhood Hits	701	Shared Neighborhood Hits	655
SwissProt Accessions	Q9BUB5, O00312, Q5TC06, Q6V0N6	Gene names	MKNK1, MNK1
Domain Architecture
Description	MAP kinase-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (Mnk1).

M3K2_HUMAN
NC score	0.708168 (rank : 277)	θ value	7.09661e-13 (rank : 499)
Query Neighborhood Hits	2923	Target Neighborhood Hits	849	Shared Neighborhood Hits	787
SwissProt Accessions	Q9Y2U5, Q53QL9, Q53S75, Q59GZ6, Q8NC32, Q9NYK3	Gene names	MAP3K2, MAPKKK2, MEKK2
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2).

M3K5_MOUSE
NC score	0.708149 (rank : 278)	θ value	4.91457e-14 (rank : 450)
Query Neighborhood Hits	2923	Target Neighborhood Hits	867	Shared Neighborhood Hits	793
SwissProt Accessions	O35099	Gene names	Map3k5, Ask1, Mekk5
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5) (Apoptosis signal- regulating kinase 1) (ASK-1).

M3K5_HUMAN
NC score	0.708131 (rank : 279)	θ value	3.76295e-14 (rank : 447)
Query Neighborhood Hits	2923	Target Neighborhood Hits	868	Shared Neighborhood Hits	793
SwissProt Accessions	Q99683, Q5THN3, Q99461	Gene names	MAP3K5, ASK1, MAPKKK5, MEKK5
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5) (Apoptosis signal- regulating kinase 1) (ASK-1).

MAST2_HUMAN
NC score	0.707539 (rank : 280)	θ value	8.38298e-14 (rank : 466)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1189	Shared Neighborhood Hits	898
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

KPCZ_MOUSE
NC score	0.706873 (rank : 281)	θ value	5.8054e-15 (rank : 414)
Query Neighborhood Hits	2923	Target Neighborhood Hits	882	Shared Neighborhood Hits	787
SwissProt Accessions	Q02956	Gene names	Prkcz, Pkcz
Domain Architecture
Description	Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta).

KPCZ_HUMAN
NC score	0.706765 (rank : 282)	θ value	5.8054e-15 (rank : 413)
Query Neighborhood Hits	2923	Target Neighborhood Hits	884	Shared Neighborhood Hits	786
SwissProt Accessions	Q05513, Q15207, Q5SYT5, Q969S4	Gene names	PRKCZ, PKC2
Domain Architecture
Description	Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta).

M3K15_HUMAN
NC score	0.706748 (rank : 283)	θ value	1.09485e-13 (rank : 473)
Query Neighborhood Hits	2923	Target Neighborhood Hits	914	Shared Neighborhood Hits	815
SwissProt Accessions	Q6ZN16, Q5JPR4, Q6ZMV3	Gene names	MAP3K15
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 15 (EC 2.7.11.25) (MAPK/ERK kinase kinase 15) (MEK kinase 15) (MEKK 15).

CDKL4_HUMAN
NC score	0.706468 (rank : 284)	θ value	3.28887e-18 (rank : 317)
Query Neighborhood Hits	2923	Target Neighborhood Hits	828	Shared Neighborhood Hits	775
SwissProt Accessions	Q5MAI5	Gene names	CDKL4
Domain Architecture	No domain graphic available
Description	Cyclin-dependent kinase-like 4 (EC 2.7.11.22).

GRK7_HUMAN
NC score	0.705963 (rank : 285)	θ value	2.98157e-11 (rank : 579)
Query Neighborhood Hits	2923	Target Neighborhood Hits	820	Shared Neighborhood Hits	773
SwissProt Accessions	Q8WTQ7	Gene names	GRK7, GPRK7
Domain Architecture
Description	G protein-coupled receptor kinase 7 precursor (EC 2.7.11.16) (G protein-coupled receptor kinase GRK7).

MAST4_HUMAN
NC score	0.705786 (rank : 286)	θ value	1.29331e-14 (rank : 426)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1804	Shared Neighborhood Hits	1098
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

MUSK_HUMAN
NC score	0.705582 (rank : 287)	θ value	6.40375e-22 (rank : 222)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1074	Shared Neighborhood Hits	1002
SwissProt Accessions	O15146	Gene names	MUSK
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (Muscle-specific kinase receptor) (MuSK).

M3K8_HUMAN
NC score	0.704865 (rank : 288)	θ value	4.16044e-13 (rank : 494)
Query Neighborhood Hits	2923	Target Neighborhood Hits	807	Shared Neighborhood Hits	769
SwissProt Accessions	P41279, Q14275, Q9HC81	Gene names	MAP3K8, COT
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 8 (EC 2.7.11.25) (COT proto-oncogene serine/threonine-protein kinase) (C-COT) (Cancer Osaka thyroid oncogene).

ST38L_HUMAN
NC score	0.704700 (rank : 289)	θ value	2.88119e-14 (rank : 445)
Query Neighborhood Hits	2923	Target Neighborhood Hits	824	Shared Neighborhood Hits	777
SwissProt Accessions	Q9Y2H1, Q8TBX7	Gene names	STK38L, KIAA0965, NDR2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 38-like (EC 2.7.11.1) (NDR2 protein kinase) (Nuclear Dbf2-related kinase 2).

YSK4_HUMAN
NC score	0.704547 (rank : 290)	θ value	1.99529e-15 (rank : 401)
Query Neighborhood Hits	2923	Target Neighborhood Hits	921	Shared Neighborhood Hits	819
SwissProt Accessions	Q56UN5, Q56UN1, Q56UN2, Q56UN3, Q56UN4, Q8N4E9, Q9H5T2	Gene names	YSK4, RCK
Domain Architecture	No domain graphic available
Description	SPS1/STE20-related protein kinase YSK4 (EC 2.7.11.1) (Regulated in COPD, protein kinase).

MAST1_HUMAN
NC score	0.704362 (rank : 291)	θ value	1.58096e-12 (rank : 517)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1146	Shared Neighborhood Hits	880
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

M3K14_HUMAN
NC score	0.704163 (rank : 292)	θ value	2.61198e-07 (rank : 835)
Query Neighborhood Hits	2923	Target Neighborhood Hits	887	Shared Neighborhood Hits	807
SwissProt Accessions	Q99558, Q8IYN1	Gene names	MAP3K14, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF- kappa beta-inducing kinase) (Serine/threonine-protein kinase NIK) (HsNIK).

STK38_HUMAN
NC score	0.704028 (rank : 293)	θ value	1.86753e-13 (rank : 486)
Query Neighborhood Hits	2923	Target Neighborhood Hits	840	Shared Neighborhood Hits	784
SwissProt Accessions	Q15208	Gene names	STK38, NDR1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1 protein kinase) (Nuclear Dbf2-related kinase 1).

MAST1_MOUSE
NC score	0.703881 (rank : 294)	θ value	3.52202e-12 (rank : 540)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1123	Shared Neighborhood Hits	863
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

M3K8_MOUSE
NC score	0.703792 (rank : 295)	θ value	2.98157e-11 (rank : 583)
Query Neighborhood Hits	2923	Target Neighborhood Hits	815	Shared Neighborhood Hits	767
SwissProt Accessions	Q07174	Gene names	Map3k8, Cot
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 8 (EC 2.7.11.25) (COT proto-oncogene serine/threonine-protein kinase) (C-COT) (Cancer Osaka thyroid oncogene).

STK38_MOUSE
NC score	0.703494 (rank : 296)	θ value	1.2105e-12 (rank : 510)
Query Neighborhood Hits	2923	Target Neighborhood Hits	838	Shared Neighborhood Hits	784
SwissProt Accessions	Q91VJ4	Gene names	Stk38, Ndr1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1 protein kinase) (Nuclear Dbf2-related kinase 1).

PDK1L_HUMAN
NC score	0.703055 (rank : 297)	θ value	2.79066e-09 (rank : 704)
Query Neighborhood Hits	2923	Target Neighborhood Hits	821	Shared Neighborhood Hits	766
SwissProt Accessions	Q8N165, Q5T2I0, Q8NDB3	Gene names	PDIK1L, CLIK1L
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PDIK1L (EC 2.7.11.1) (PDLIM1- interacting kinase 1-like).

PDK1L_MOUSE
NC score	0.702994 (rank : 298)	θ value	4.76016e-09 (rank : 723)
Query Neighborhood Hits	2923	Target Neighborhood Hits	821	Shared Neighborhood Hits	766
SwissProt Accessions	Q8QZR7, Q3URF0, Q8BKB3	Gene names	Pdik1l
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PDIK1L (EC 2.7.11.1) (PDLIM1- interacting kinase 1-like).

STK3_MOUSE
NC score	0.702880 (rank : 299)	θ value	1.92812e-18 (rank : 309)
Query Neighborhood Hits	2923	Target Neighborhood Hits	869	Shared Neighborhood Hits	795
SwissProt Accessions	Q9JI10, Q60877, Q80UG4, Q8CI58	Gene names	Stk3, Mess1, Mst2
Domain Architecture
Description	Serine/threonine-protein kinase 3 (EC 2.7.11.1) (STE20-like kinase MST2) (MST-2) (Mammalian STE20-like protein kinase 2).

STK40_HUMAN
NC score	0.702857 (rank : 300)	θ value	4.59992e-12 (rank : 544)
Query Neighborhood Hits	2923	Target Neighborhood Hits	751	Shared Neighborhood Hits	718
SwissProt Accessions	Q8N2I9, Q5VTK8, Q5VTK9, Q6ZMN1, Q8N2J8, Q8N3I6, Q96HN6, Q96I44, Q9BSA3, Q9H7H6	Gene names	STK40, SHIK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 40 (EC 2.7.11.1) (SINK-homologous serine/threonine-protein kinase).

E2AK2_MOUSE
NC score	0.702833 (rank : 301)	θ value	9.92553e-07 (rank : 875)
Query Neighborhood Hits	2923	Target Neighborhood Hits	864	Shared Neighborhood Hits	784
SwissProt Accessions	Q03963, Q61742, Q62026	Gene names	Eif2ak2, Pkr, Prkr, Tik
Domain Architecture
Description	Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Interferon-inducible RNA-dependent protein kinase) (Protein kinase RNA-activated) (PKR) (p68 kinase) (P1/eIF-2A protein kinase) (Serine/threonine-protein kinase TIK).

TLK2_HUMAN
NC score	0.702782 (rank : 302)	θ value	4.76016e-09 (rank : 726)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1044	Shared Neighborhood Hits	878
SwissProt Accessions	Q86UE8, Q9UKI7, Q9Y4F7	Gene names	TLK2
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (Tousled- like kinase 2) (PKU-alpha).

MUSK_MOUSE
NC score	0.702705 (rank : 303)	θ value	1.86321e-21 (rank : 233)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1057	Shared Neighborhood Hits	994
SwissProt Accessions	Q61006, Q61005, Q61987, Q61988	Gene names	Musk, Nsk2
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific kinase receptor) (MuSK).

STK40_MOUSE
NC score	0.702624 (rank : 304)	θ value	4.59992e-12 (rank : 545)
Query Neighborhood Hits	2923	Target Neighborhood Hits	751	Shared Neighborhood Hits	717
SwissProt Accessions	Q7TNL3, Q3U3G3, Q811D6, Q8BKT1, Q9D7K3	Gene names	Stk40, Lyk4
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 40 (EC 2.7.11.1) (Serine/threonine- protein kinase lyk4).

TLK2_MOUSE
NC score	0.702489 (rank : 305)	θ value	4.76016e-09 (rank : 727)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1088	Shared Neighborhood Hits	913
SwissProt Accessions	O55047, Q9D5Y5	Gene names	Tlk2
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (Tousled- like kinase 2).

STK3_HUMAN
NC score	0.702329 (rank : 306)	θ value	4.29542e-18 (rank : 324)
Query Neighborhood Hits	2923	Target Neighborhood Hits	861	Shared Neighborhood Hits	794
SwissProt Accessions	Q13188, Q15445, Q15801, Q96FM6	Gene names	STK3, MST2
Domain Architecture
Description	Serine/threonine-protein kinase 3 (EC 2.7.11.1) (STE20-like kinase MST2) (MST-2) (Mammalian STE20-like protein kinase 2) (Serine/threonine-protein kinase Krs-1).

STK4_MOUSE
NC score	0.702307 (rank : 307)	θ value	2.97466e-19 (rank : 289)
Query Neighborhood Hits	2923	Target Neighborhood Hits	873	Shared Neighborhood Hits	792
SwissProt Accessions	Q9JI11	Gene names	Stk4, Mst1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 4 (EC 2.7.11.1) (STE20-like kinase MST1) (MST-1) (Mammalian STE20-like protein kinase 1).

STK4_HUMAN
NC score	0.702087 (rank : 308)	θ value	3.28887e-18 (rank : 320)
Query Neighborhood Hits	2923	Target Neighborhood Hits	870	Shared Neighborhood Hits	791
SwissProt Accessions	Q13043, Q15802, Q4G156, Q5H982, Q6PD60, Q9BR32, Q9NTZ4	Gene names	STK4, MST1
Domain Architecture
Description	Serine/threonine-protein kinase 4 (EC 2.7.11.1) (STE20-like kinase MST1) (MST-1) (Mammalian STE20-like protein kinase 1) (Serine/threonine-protein kinase Krs-2).

CDC2_HUMAN
NC score	0.701881 (rank : 309)	θ value	1.38178e-16 (rank : 360)
Query Neighborhood Hits	2923	Target Neighborhood Hits	842	Shared Neighborhood Hits	787
SwissProt Accessions	P06493, O60764	Gene names	CDC2
Domain Architecture
Description	Cell division control protein 2 homolog (EC 2.7.11.22) (EC 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1).

CDC2_MOUSE
NC score	0.701189 (rank : 310)	θ value	2.7842e-17 (rank : 345)
Query Neighborhood Hits	2923	Target Neighborhood Hits	838	Shared Neighborhood Hits	784
SwissProt Accessions	P11440, P70337, Q3TI12	Gene names	Cdc2, Cdc2a
Domain Architecture
Description	Cell division control protein 2 homolog (EC 2.7.11.22) (EC 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1).

TLK1_HUMAN
NC score	0.701169 (rank : 311)	θ value	6.21693e-09 (rank : 731)
Query Neighborhood Hits	2923	Target Neighborhood Hits	967	Shared Neighborhood Hits	842
SwissProt Accessions	Q9UKI8, Q14150, Q8N591, Q9NYH2, Q9Y4F6	Gene names	TLK1, KIAA0137
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1) (Tousled- like kinase 1) (PKU-beta).

MAK_MOUSE
NC score	0.701121 (rank : 312)	θ value	5.8054e-15 (rank : 415)
Query Neighborhood Hits	2923	Target Neighborhood Hits	873	Shared Neighborhood Hits	796
SwissProt Accessions	Q04859	Gene names	Mak, Rck
Domain Architecture
Description	Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male germ cell- associated kinase) (Protein kinase RCK).

TLK1_MOUSE
NC score	0.700934 (rank : 313)	θ value	6.21693e-09 (rank : 732)
Query Neighborhood Hits	2923	Target Neighborhood Hits	947	Shared Neighborhood Hits	821
SwissProt Accessions	Q8C0V0	Gene names	Tlk1
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1) (Tousled- like kinase 1).

ICK_MOUSE
NC score	0.700734 (rank : 314)	θ value	5.43371e-13 (rank : 497)
Query Neighborhood Hits	2923	Target Neighborhood Hits	860	Shared Neighborhood Hits	795
SwissProt Accessions	Q9JKV2, Q8K138	Gene names	Ick
Domain Architecture
Description	Serine/threonine-protein kinase ICK (EC 2.7.11.22) (Intestinal cell kinase) (mICK) (MAK-related kinase) (MRK).

CDK3_HUMAN
NC score	0.700290 (rank : 315)	θ value	9.90251e-15 (rank : 422)
Query Neighborhood Hits	2923	Target Neighborhood Hits	843	Shared Neighborhood Hits	787
SwissProt Accessions	Q00526	Gene names	CDK3
Domain Architecture
Description	Cell division protein kinase 3 (EC 2.7.11.22).

MAK_HUMAN
NC score	0.700213 (rank : 316)	θ value	4.44505e-15 (rank : 411)
Query Neighborhood Hits	2923	Target Neighborhood Hits	857	Shared Neighborhood Hits	787
SwissProt Accessions	P20794, Q9NUH7	Gene names	MAK
Domain Architecture
Description	Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male germ cell- associated kinase).

ICK_HUMAN
NC score	0.700180 (rank : 317)	θ value	1.58096e-12 (rank : 515)
Query Neighborhood Hits	2923	Target Neighborhood Hits	867	Shared Neighborhood Hits	793
SwissProt Accessions	Q9UPZ9, O75985, Q5THL2, Q8IYH8, Q9BX17, Q9NYX3	Gene names	ICK, KIAA0936
Domain Architecture
Description	Serine/threonine-protein kinase ICK (EC 2.7.11.22) (Intestinal cell kinase) (hICK) (MAK-related kinase) (MRK) (Laryngeal cancer kinase 2) (LCK2).

ST38L_MOUSE
NC score	0.699834 (rank : 318)	θ value	2.0648e-12 (rank : 529)
Query Neighborhood Hits	2923	Target Neighborhood Hits	821	Shared Neighborhood Hits	777
SwissProt Accessions	Q7TSE6, Q6P6K6, Q8BWK4	Gene names	Stk38l, Ndr2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 38-like (EC 2.7.11.1) (NDR2 protein kinase) (Nuclear Dbf2-related kinase 2).

M3K14_MOUSE
NC score	0.699765 (rank : 319)	θ value	1.17247e-07 (rank : 809)
Query Neighborhood Hits	2923	Target Neighborhood Hits	889	Shared Neighborhood Hits	792
SwissProt Accessions	Q9WUL6	Gene names	Map3k14, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF- kappa beta-inducing kinase) (Serine/threonine-protein kinase NIK).

STK24_HUMAN
NC score	0.699570 (rank : 320)	θ value	5.25075e-16 (rank : 382)
Query Neighborhood Hits	2923	Target Neighborhood Hits	853	Shared Neighborhood Hits	791
SwissProt Accessions	Q9Y6E0, O14840	Gene names	STK24, MST3, STK3
Domain Architecture
Description	Serine/threonine-protein kinase 24 (EC 2.7.11.1) (STE20-like kinase MST3) (MST-3) (Mammalian STE20-like protein kinase 3).

NEK9_HUMAN
NC score	0.699498 (rank : 321)	θ value	3.07829e-16 (rank : 373)
Query Neighborhood Hits	2923	Target Neighborhood Hits	900	Shared Neighborhood Hits	800
SwissProt Accessions	Q8TD19, Q52LK6, Q8NCN0, Q8TCY4, Q9UPI4, Q9Y6S4, Q9Y6S5, Q9Y6S6	Gene names	NEK9, KIAA1995, NEK8, NERCC
Domain Architecture
Description	Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (NimA-related protein kinase 9) (Never in mitosis A-related kinase 9) (Nercc1 kinase) (NIMA-related kinase 8) (Nek8).

MASTL_HUMAN
NC score	0.699152 (rank : 322)	θ value	1.74796e-11 (rank : 571)
Query Neighborhood Hits	2923	Target Neighborhood Hits	894	Shared Neighborhood Hits	791
SwissProt Accessions	Q96GX5, Q5T8D5, Q5T8D7, Q8NCD6, Q96SJ5	Gene names	MASTL, THC2
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase-like (EC 2.7.11.1).

STK24_MOUSE
NC score	0.699099 (rank : 323)	θ value	8.95645e-16 (rank : 394)
Query Neighborhood Hits	2923	Target Neighborhood Hits	856	Shared Neighborhood Hits	791
SwissProt Accessions	Q99KH8	Gene names	Stk24
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 24 (EC 2.7.11.1).

OXSR1_HUMAN
NC score	0.698971 (rank : 324)	θ value	2.69671e-12 (rank : 538)
Query Neighborhood Hits	2923	Target Neighborhood Hits	874	Shared Neighborhood Hits	797
SwissProt Accessions	O95747, Q3LR53, Q7Z501, Q9UPQ1	Gene names	OXSR1, KIAA1101, OSR1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress- responsive 1 protein).

MST4_MOUSE
NC score	0.698824 (rank : 325)	θ value	8.95645e-16 (rank : 393)
Query Neighborhood Hits	2923	Target Neighborhood Hits	860	Shared Neighborhood Hits	790
SwissProt Accessions	Q99JT2	Gene names	Mst4
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MST4 (EC 2.7.11.1) (STE20-like kinase MST4) (MST-4) (Mammalian STE20-like protein kinase 4).

MST4_HUMAN
NC score	0.698782 (rank : 326)	θ value	8.95645e-16 (rank : 392)
Query Neighborhood Hits	2923	Target Neighborhood Hits	852	Shared Neighborhood Hits	788
SwissProt Accessions	Q9P289, Q3ZB77, Q9BXC4	Gene names	MST4, MASK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MST4 (EC 2.7.11.1) (STE20-like kinase MST4) (MST-4) (Mammalian STE20-like protein kinase 4) (Serine/threonine-protein kinase MASK) (Mst3 and SOK1-related kinase).

MK15_HUMAN
NC score	0.698763 (rank : 327)	θ value	1.80466e-16 (rank : 364)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1038	Shared Neighborhood Hits	836
SwissProt Accessions	Q8TD08, Q2TCF9, Q8N362	Gene names	MAPK15, ERK8
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 8).

OXSR1_MOUSE
NC score	0.698719 (rank : 328)	θ value	2.69671e-12 (rank : 539)
Query Neighborhood Hits	2923	Target Neighborhood Hits	865	Shared Neighborhood Hits	793
SwissProt Accessions	Q6P9R2, Q8BVZ9, Q8C0B9	Gene names	Oxsr1, Osr1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress- responsive 1 protein).

MK15_MOUSE
NC score	0.698585 (rank : 329)	θ value	2.0648e-12 (rank : 527)
Query Neighborhood Hits	2923	Target Neighborhood Hits	843	Shared Neighborhood Hits	780
SwissProt Accessions	Q80Y86	Gene names	Mapk15, Erk7
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 7).

MASTL_MOUSE
NC score	0.698460 (rank : 330)	θ value	8.67504e-11 (rank : 616)
Query Neighborhood Hits	2923	Target Neighborhood Hits	862	Shared Neighborhood Hits	785
SwissProt Accessions	Q8C0P0, Q5RJW0, Q6NXX9, Q8BVF3, Q9CZH9, Q9D9V0	Gene names	Mastl
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase-like (EC 2.7.11.1).

NEK9_MOUSE
NC score	0.698423 (rank : 331)	θ value	2.20605e-14 (rank : 438)
Query Neighborhood Hits	2923	Target Neighborhood Hits	890	Shared Neighborhood Hits	798
SwissProt Accessions	Q8K1R7, Q8R3P1	Gene names	Nek9, Nercc
Domain Architecture
Description	Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (NimA-related protein kinase 9) (Never in mitosis A-related kinase 9).

STK39_MOUSE
NC score	0.697905 (rank : 332)	θ value	1.63604e-09 (rank : 688)
Query Neighborhood Hits	2923	Target Neighborhood Hits	915	Shared Neighborhood Hits	810
SwissProt Accessions	Q9Z1W9, Q80W13	Gene names	Stk39, Spak
Domain Architecture
Description	STE20/SPS1-related proline-alanine-rich protein kinase (EC 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39).

ARBK1_HUMAN
NC score	0.697809 (rank : 333)	θ value	4.0297e-08 (rank : 767)
Query Neighborhood Hits	2923	Target Neighborhood Hits	859	Shared Neighborhood Hits	782
SwissProt Accessions	P25098, Q13837	Gene names	ADRBK1, BARK, BARK1, GRK2
Domain Architecture
Description	Beta-adrenergic receptor kinase 1 (EC 2.7.11.15) (Beta-ARK-1) (G- protein coupled receptor kinase 2).

ARBK2_HUMAN
NC score	0.697645 (rank : 334)	θ value	1.38499e-08 (rank : 744)
Query Neighborhood Hits	2923	Target Neighborhood Hits	849	Shared Neighborhood Hits	781
SwissProt Accessions	P35626, Q9UGW9	Gene names	ADRBK2, BARK2, GRK3
Domain Architecture
Description	Beta-adrenergic receptor kinase 2 (EC 2.7.11.15) (Beta-ARK-2) (G- protein-coupled receptor kinase 3).

SLK_MOUSE
NC score	0.697627 (rank : 335)	θ value	2.88119e-14 (rank : 444)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1798	Shared Neighborhood Hits	1173
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

STK39_HUMAN
NC score	0.697444 (rank : 336)	θ value	1.63604e-09 (rank : 687)
Query Neighborhood Hits	2923	Target Neighborhood Hits	882	Shared Neighborhood Hits	796
SwissProt Accessions	Q9UEW8, O14774, Q9UER4	Gene names	STK39, SPAK
Domain Architecture
Description	STE20/SPS1-related proline-alanine-rich protein kinase (EC 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39) (DCHT).

CDK2_HUMAN
NC score	0.696975 (rank : 337)	θ value	6.41864e-14 (rank : 454)
Query Neighborhood Hits	2923	Target Neighborhood Hits	832	Shared Neighborhood Hits	780
SwissProt Accessions	P24941	Gene names	CDK2
Domain Architecture
Description	Cell division protein kinase 2 (EC 2.7.11.22) (p33 protein kinase).

CDK3_MOUSE
NC score	0.696858 (rank : 338)	θ value	8.67504e-11 (rank : 610)
Query Neighborhood Hits	2923	Target Neighborhood Hits	829	Shared Neighborhood Hits	778
SwissProt Accessions	Q80YP0	Gene names	Cdk3
Domain Architecture	No domain graphic available
Description	Truncated cell division protein kinase 3 homolog.

ARBK1_MOUSE
NC score	0.696593 (rank : 339)	θ value	4.0297e-08 (rank : 768)
Query Neighborhood Hits	2923	Target Neighborhood Hits	849	Shared Neighborhood Hits	777
SwissProt Accessions	Q99MK8, Q99LL8	Gene names	Adrbk1, Grk2
Domain Architecture
Description	Beta-adrenergic receptor kinase 1 (EC 2.7.11.15) (Beta-ARK-1) (G- protein-coupled receptor kinase 2).

SLK_HUMAN
NC score	0.696280 (rank : 340)	θ value	1.86753e-13 (rank : 485)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1775	Shared Neighborhood Hits	1156
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

STK25_HUMAN
NC score	0.696260 (rank : 341)	θ value	2.60593e-15 (rank : 406)
Query Neighborhood Hits	2923	Target Neighborhood Hits	853	Shared Neighborhood Hits	791
SwissProt Accessions	O00506, Q15522, Q5BJF1	Gene names	STK25, SOK1, YSK1
Domain Architecture
Description	Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Sterile 20/oxidant stress-response kinase 1) (Ste20/oxidant stress response kinase 1) (SOK-1) (Ste20-like kinase).

KPCA_MOUSE
NC score	0.696253 (rank : 342)	θ value	2.5182e-18 (rank : 315)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1067	Shared Neighborhood Hits	791
SwissProt Accessions	P20444	Gene names	Prkca, Pkca
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

DMPK_MOUSE
NC score	0.695962 (rank : 343)	θ value	1.58096e-12 (rank : 513)
Query Neighborhood Hits	2923	Target Neighborhood Hits	908	Shared Neighborhood Hits	821
SwissProt Accessions	P54265	Gene names	Dmpk, Dm15, Mdpk
Domain Architecture
Description	Myotonin-protein kinase (EC 2.7.11.1) (Myotonic dystrophy protein kinase) (MDPK) (DM-kinase) (DMK) (DMPK) (MT-PK).

DMPK_HUMAN
NC score	0.695935 (rank : 344)	θ value	1.86753e-13 (rank : 480)
Query Neighborhood Hits	2923	Target Neighborhood Hits	944	Shared Neighborhood Hits	830
SwissProt Accessions	Q09013, Q16205	Gene names	DMPK, MDPK
Domain Architecture
Description	Myotonin-protein kinase (EC 2.7.11.1) (Myotonic dystrophy protein kinase) (MDPK) (DM-kinase) (DMK) (DMPK) (MT-PK).

STK25_MOUSE
NC score	0.695840 (rank : 345)	θ value	1.29331e-14 (rank : 431)
Query Neighborhood Hits	2923	Target Neighborhood Hits	851	Shared Neighborhood Hits	790
SwissProt Accessions	Q9Z2W1	Gene names	Stk25, Sok1
Domain Architecture
Description	Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Sterile 20/oxidant stress-response kinase 1) (Ste20/oxidant stress response kinase 1) (SOK-1) (Ste20-like kinase).

STK35_HUMAN
NC score	0.695228 (rank : 346)	θ value	1.87187e-05 (rank : 949)
Query Neighborhood Hits	2923	Target Neighborhood Hits	825	Shared Neighborhood Hits	767
SwissProt Accessions	Q8TDR2, Q5T3R1, Q5T3R2, Q96AB4, Q9BZ06	Gene names	STK35, CLIK1, PDIK1
Domain Architecture
Description	Serine/threonine-protein kinase 35 (EC 2.7.11.1) (CLP-36-interacting kinase) (Clik1) (PDLIM1-interacting kinase 1).

KPCA_HUMAN
NC score	0.695170 (rank : 347)	θ value	2.5182e-18 (rank : 314)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1070	Shared Neighborhood Hits	794
SwissProt Accessions	P17252, Q15137, Q96RE4	Gene names	PRKCA, PKCA, PRKACA
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

CSK21_MOUSE
NC score	0.695153 (rank : 348)	θ value	1.63225e-17 (rank : 342)
Query Neighborhood Hits	2923	Target Neighborhood Hits	770	Shared Neighborhood Hits	741
SwissProt Accessions	Q60737	Gene names	Csnk2a1, Ckiia
Domain Architecture
Description	Casein kinase II subunit alpha (EC 2.7.11.1) (CK II).

CDK7_HUMAN
NC score	0.694981 (rank : 349)	θ value	6.00763e-12 (rank : 549)
Query Neighborhood Hits	2923	Target Neighborhood Hits	833	Shared Neighborhood Hits	773
SwissProt Accessions	P50613, Q9BS60, Q9UE19	Gene names	CDK7, MO15
Domain Architecture
Description	Cell division protein kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (CDK- activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 kDa protein kinase) (P39 Mo15) (STK1) (CAK1).

CSK21_HUMAN
NC score	0.694976 (rank : 350)	θ value	4.29542e-18 (rank : 321)
Query Neighborhood Hits	2923	Target Neighborhood Hits	772	Shared Neighborhood Hits	741
SwissProt Accessions	P68400, P19138, P20426, Q14013	Gene names	CSNK2A1, CK2A1
Domain Architecture	No domain graphic available
Description	Casein kinase II subunit alpha (EC 2.7.11.1) (CK II).

CDK7_MOUSE
NC score	0.694788 (rank : 351)	θ value	6.00763e-12 (rank : 550)
Query Neighborhood Hits	2923	Target Neighborhood Hits	835	Shared Neighborhood Hits	773
SwissProt Accessions	Q03147, Q99KK3	Gene names	Cdk7, Cdkn7, Crk4, Mo15, Mpk-7
Domain Architecture
Description	Cell division protein kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (CDK- activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 kDa protein kinase) (P39 Mo15) (Protein-tyrosine kinase MPK-7) (CR4 protein kinase) (CRK4).

PMYT1_MOUSE
NC score	0.694498 (rank : 352)	θ value	4.0297e-08 (rank : 772)
Query Neighborhood Hits	2923	Target Neighborhood Hits	910	Shared Neighborhood Hits	799
SwissProt Accessions	Q9ESG9, Q8R3L4	Gene names	Pkmyt1, Myt1
Domain Architecture	No domain graphic available
Description	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase).

CD2L7_HUMAN
NC score	0.694286 (rank : 353)	θ value	2.28291e-11 (rank : 575)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1275	Shared Neighborhood Hits	989
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

VGFR1_MOUSE
NC score	0.694244 (rank : 354)	θ value	1.6852e-22 (rank : 211)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1118	Shared Neighborhood Hits	1032
SwissProt Accessions	P35969, O55094, Q61517	Gene names	Flt1, Emrk2, Flt
Domain Architecture
Description	Vascular endothelial growth factor receptor 1 precursor (EC 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) (Embryonic receptor kinase 2).

MOK_HUMAN
NC score	0.693922 (rank : 355)	θ value	2.35696e-16 (rank : 366)
Query Neighborhood Hits	2923	Target Neighborhood Hits	807	Shared Neighborhood Hits	763
SwissProt Accessions	Q9UQ07, Q92790, Q93067	Gene names	RAGE, MOK, RAGE1
Domain Architecture
Description	MAPK/MAK/MRK overlapping kinase (EC 2.7.11.22) (MOK protein kinase) (Renal tumor antigen 1) (RAGE-1).

MK12_MOUSE
NC score	0.693868 (rank : 356)	θ value	4.91457e-14 (rank : 451)
Query Neighborhood Hits	2923	Target Neighborhood Hits	835	Shared Neighborhood Hits	778
SwissProt Accessions	O08911, Q9D0M4	Gene names	Mapk12, Sapk3
Domain Architecture
Description	Mitogen-activated protein kinase 12 (EC 2.7.11.24) (Extracellular signal-regulated kinase 6) (ERK-6) (Stress-activated protein kinase 3) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma).

MP2K5_MOUSE
NC score	0.693766 (rank : 357)	θ value	4.30538e-10 (rank : 651)
Query Neighborhood Hits	2923	Target Neighborhood Hits	840	Shared Neighborhood Hits	780
SwissProt Accessions	Q9WVS7, Q8CFM3, Q8K360, Q9D222	Gene names	Map2k5, Mek5, Mkk5, Prkmk5
Domain Architecture	No domain graphic available
Description	Dual specificity mitogen-activated protein kinase kinase 5 (EC 2.7.12.2) (MAP kinase kinase 5) (MAPKK 5) (MAPK/ERK kinase 5).

FGFR1_HUMAN
NC score	0.693759 (rank : 358)	θ value	8.38298e-14 (rank : 465)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1069	Shared Neighborhood Hits	1005
SwissProt Accessions	P11362, P17049, Q02063, Q02065, Q14306, Q14307, Q8N685	Gene names	FGFR1, FGFBR, FLG, FLT2
Domain Architecture
Description	Basic fibroblast growth factor receptor 1 precursor (EC 2.7.10.1) (FGFR-1) (bFGF-R) (Fms-like tyrosine kinase 2) (c-fgr) (CD331 antigen).

CDK6_MOUSE
NC score	0.693755 (rank : 359)	θ value	2.79066e-09 (rank : 699)
Query Neighborhood Hits	2923	Target Neighborhood Hits	837	Shared Neighborhood Hits	782
SwissProt Accessions	Q64261, Q9R1D2, Q9R1D3	Gene names	Cdk6, Crk2
Domain Architecture
Description	Cell division protein kinase 6 (EC 2.7.11.22) (Serine/threonine- protein kinase PLSTIRE) (CRK2).

CDK6_HUMAN
NC score	0.693612 (rank : 360)	θ value	3.64472e-09 (rank : 710)
Query Neighborhood Hits	2923	Target Neighborhood Hits	837	Shared Neighborhood Hits	782
SwissProt Accessions	Q00534	Gene names	CDK6
Domain Architecture
Description	Cell division protein kinase 6 (EC 2.7.11.22) (Serine/threonine- protein kinase PLSTIRE).

FGFR1_MOUSE
NC score	0.693521 (rank : 361)	θ value	7.58209e-15 (rank : 419)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1068	Shared Neighborhood Hits	1004
SwissProt Accessions	P16092, Q01736, Q61562, Q80T10	Gene names	Fgfr1, Flg
Domain Architecture
Description	Basic fibroblast growth factor receptor 1 precursor (EC 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) (CD331 antigen).

MK12_HUMAN
NC score	0.693331 (rank : 362)	θ value	1.58096e-12 (rank : 518)
Query Neighborhood Hits	2923	Target Neighborhood Hits	830	Shared Neighborhood Hits	776
SwissProt Accessions	P53778, Q14260, Q99588, Q99672	Gene names	MAPK12, ERK6, SAPK3
Domain Architecture
Description	Mitogen-activated protein kinase 12 (EC 2.7.11.24) (Extracellular signal-regulated kinase 6) (ERK-6) (ERK5) (Stress-activated protein kinase 3) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma).

PCTK3_MOUSE
NC score	0.693315 (rank : 363)	θ value	2.35696e-16 (rank : 367)
Query Neighborhood Hits	2923	Target Neighborhood Hits	834	Shared Neighborhood Hits	776
SwissProt Accessions	Q04899	Gene names	Pctk3
Domain Architecture
Description	Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22) (PCTAIRE- motif protein kinase 3).

PFTK1_MOUSE
NC score	0.693296 (rank : 364)	θ value	1.58096e-12 (rank : 520)
Query Neighborhood Hits	2923	Target Neighborhood Hits	835	Shared Neighborhood Hits	781
SwissProt Accessions	O35495, O35848	Gene names	Pftk1
Domain Architecture
Description	Serine/threonine-protein kinase PFTAIRE-1 (EC 2.7.11.22).

GSK3A_HUMAN
NC score	0.693245 (rank : 365)	θ value	1.133e-10 (rank : 622)
Query Neighborhood Hits	2923	Target Neighborhood Hits	835	Shared Neighborhood Hits	769
SwissProt Accessions	P49840, O14959	Gene names	GSK3A
Domain Architecture
Description	Glycogen synthase kinase-3 alpha (EC 2.7.11.26) (GSK-3 alpha).

CDK2_MOUSE
NC score	0.693166 (rank : 366)	θ value	1.09485e-13 (rank : 471)
Query Neighborhood Hits	2923	Target Neighborhood Hits	828	Shared Neighborhood Hits	776
SwissProt Accessions	P97377, O55105	Gene names	Cdk2
Domain Architecture
Description	Cell division protein kinase 2 (EC 2.7.11.22).

PFTK1_HUMAN
NC score	0.693065 (rank : 367)	θ value	1.2105e-12 (rank : 508)
Query Neighborhood Hits	2923	Target Neighborhood Hits	834	Shared Neighborhood Hits	778
SwissProt Accessions	O94921, Q75N06, Q75N22, Q8N764, Q9H3D7, Q9UDR0	Gene names	PFTK1, KIAA0834
Domain Architecture
Description	Serine/threonine-protein kinase PFTAIRE-1 (EC 2.7.11.22).

CDK5_HUMAN
NC score	0.693038 (rank : 368)	θ value	1.058e-16 (rank : 354)
Query Neighborhood Hits	2923	Target Neighborhood Hits	826	Shared Neighborhood Hits	771
SwissProt Accessions	Q00535	Gene names	CDK5
Domain Architecture
Description	Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE).

M4K1_HUMAN
NC score	0.692949 (rank : 369)	θ value	1.09485e-13 (rank : 474)
Query Neighborhood Hits	2923	Target Neighborhood Hits	884	Shared Neighborhood Hits	800
SwissProt Accessions	Q92918	Gene names	MAP4K1, HPK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1) (Hematopoietic progenitor kinase).

CDK5_MOUSE
NC score	0.692913 (rank : 370)	θ value	1.058e-16 (rank : 355)
Query Neighborhood Hits	2923	Target Neighborhood Hits	826	Shared Neighborhood Hits	771
SwissProt Accessions	P49615	Gene names	Cdk5, Crk6
Domain Architecture
Description	Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) (CRK6).

M4K3_HUMAN
NC score	0.692805 (rank : 371)	θ value	2.43908e-13 (rank : 489)
Query Neighborhood Hits	2923	Target Neighborhood Hits	857	Shared Neighborhood Hits	789
SwissProt Accessions	Q8IVH8, Q8IVH7, Q9UDM5, Q9Y6R5	Gene names	MAP4K3
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3) (Germinal center kinase-related protein kinase) (GLK).

VGFR1_HUMAN
NC score	0.692595 (rank : 372)	θ value	2.35151e-24 (rank : 186)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1109	Shared Neighborhood Hits	1033
SwissProt Accessions	P17948, O60722, P16057, Q12954	Gene names	FLT1, FLT, FRT
Domain Architecture
Description	Vascular endothelial growth factor receptor 1 precursor (EC 2.7.10.1) (VEGFR-1) (Vascular permeability factor receptor) (Tyrosine-protein kinase receptor FLT) (Flt-1) (Tyrosine-protein kinase FRT) (Fms-like tyrosine kinase 1).

PCTK1_HUMAN
NC score	0.692421 (rank : 373)	θ value	1.29331e-14 (rank : 428)
Query Neighborhood Hits	2923	Target Neighborhood Hits	832	Shared Neighborhood Hits	777
SwissProt Accessions	Q00536	Gene names	PCTK1
Domain Architecture
Description	Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22) (PCTAIRE- motif protein kinase 1).

MOK_MOUSE
NC score	0.692418 (rank : 374)	θ value	3.40345e-15 (rank : 407)
Query Neighborhood Hits	2923	Target Neighborhood Hits	796	Shared Neighborhood Hits	754
SwissProt Accessions	Q9WVS4, Q8CFU4	Gene names	Rage, Mok
Domain Architecture
Description	MAPK/MAK/MRK overlapping kinase (EC 2.7.11.22) (MOK protein kinase).

PCTK1_MOUSE
NC score	0.691964 (rank : 375)	θ value	2.88119e-14 (rank : 441)
Query Neighborhood Hits	2923	Target Neighborhood Hits	832	Shared Neighborhood Hits	776
SwissProt Accessions	Q04735	Gene names	Pctk1, Crk5
Domain Architecture
Description	Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22) (PCTAIRE- motif protein kinase 1) (CRK5).

GSK3B_MOUSE
NC score	0.691964 (rank : 376)	θ value	8.67504e-11 (rank : 614)
Query Neighborhood Hits	2923	Target Neighborhood Hits	800	Shared Neighborhood Hits	758
SwissProt Accessions	Q9WV60	Gene names	Gsk3b
Domain Architecture
Description	Glycogen synthase kinase-3 beta (EC 2.7.11.26) (GSK-3 beta).

GSK3B_HUMAN
NC score	0.691958 (rank : 377)	θ value	8.67504e-11 (rank : 613)
Query Neighborhood Hits	2923	Target Neighborhood Hits	801	Shared Neighborhood Hits	758
SwissProt Accessions	P49841, Q9BWH3, Q9UL47	Gene names	GSK3B
Domain Architecture
Description	Glycogen synthase kinase-3 beta (EC 2.7.11.26) (GSK-3 beta).

F5006_MOUSE
NC score	0.691897 (rank : 378)	θ value	8.40245e-06 (rank : 923)
Query Neighborhood Hits	2923	Target Neighborhood Hits	793	Shared Neighborhood Hits	753
SwissProt Accessions	Q5SYL1	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase FLJ25006 (EC 2.7.11.1).

MP2K2_HUMAN
NC score	0.691876 (rank : 379)	θ value	1.53129e-07 (rank : 821)
Query Neighborhood Hits	2923	Target Neighborhood Hits	830	Shared Neighborhood Hits	776
SwissProt Accessions	P36507	Gene names	MAP2K2, MEK2, MKK2, PRKMK2
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 2 (EC 2.7.12.2) (MAP kinase kinase 2) (MAPKK 2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK2).

E2AK2_HUMAN
NC score	0.691840 (rank : 380)	θ value	0.000786445 (rank : 1072)
Query Neighborhood Hits	2923	Target Neighborhood Hits	856	Shared Neighborhood Hits	782
SwissProt Accessions	P19525	Gene names	EIF2AK2, PKR, PRKR
Domain Architecture
Description	Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Interferon-inducible RNA-dependent protein kinase) (Protein kinase RNA-activated) (PKR) (p68 kinase) (P1/eIF-2A protein kinase).

M4K1_MOUSE
NC score	0.691741 (rank : 381)	θ value	4.44505e-15 (rank : 410)
Query Neighborhood Hits	2923	Target Neighborhood Hits	858	Shared Neighborhood Hits	792
SwissProt Accessions	P70218, Q8R3R0, Q99K62	Gene names	Map4k1, Hpk1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1) (Hematopoietic progenitor kinase) (HPK).

KPCB_MOUSE
NC score	0.691609 (rank : 382)	θ value	1.058e-16 (rank : 358)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1117	Shared Neighborhood Hits	794
SwissProt Accessions	P68404, P04410, P04411	Gene names	Prkcb1, Pkcb, Prkcb
Domain Architecture	No domain graphic available
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

CCRK_HUMAN
NC score	0.691460 (rank : 383)	θ value	2.0648e-12 (rank : 521)
Query Neighborhood Hits	2923	Target Neighborhood Hits	835	Shared Neighborhood Hits	777
SwissProt Accessions	Q8IZL9, Q5EDC4, Q5VYW1, Q9BUF4	Gene names	CCRK, CDCH
Domain Architecture	No domain graphic available
Description	Cell cycle-related kinase (EC 2.7.11.22) (Cyclin-kinase-activating kinase p42) (CDK-activating kinase p42) (CAK-kinase p42) (Cyclin- dependent protein kinase H).

M4K2_MOUSE
NC score	0.691271 (rank : 384)	θ value	3.18553e-13 (rank : 492)
Query Neighborhood Hits	2923	Target Neighborhood Hits	843	Shared Neighborhood Hits	777
SwissProt Accessions	Q61161	Gene names	Map4k2, Rab8ip
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Germinal center kinase) (GCK) (Rab8-interacting protein).

KPCB_HUMAN
NC score	0.691202 (rank : 385)	θ value	1.058e-16 (rank : 357)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1121	Shared Neighborhood Hits	795
SwissProt Accessions	P05771, O43744, P05127, Q15138, Q93060, Q9UE49, Q9UE50, Q9UEH8, Q9UJ30, Q9UJ33	Gene names	PRKCB1, PKCB, PRKCB
Domain Architecture
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

M4K2_HUMAN
NC score	0.691190 (rank : 386)	θ value	1.09485e-13 (rank : 475)
Query Neighborhood Hits	2923	Target Neighborhood Hits	850	Shared Neighborhood Hits	784
SwissProt Accessions	Q12851	Gene names	MAP4K2, GCK, RAB8IP
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Germinal center kinase) (GC kinase) (Rab8-interacting protein) (B lymphocyte serine/threonine-protein kinase).

MK14_MOUSE
NC score	0.691036 (rank : 387)	θ value	4.91457e-14 (rank : 452)
Query Neighborhood Hits	2923	Target Neighborhood Hits	838	Shared Neighborhood Hits	780
SwissProt Accessions	P47811, O08666, Q3UZS3, Q8C289, Q9JLV8, Q9QZ80	Gene names	Mapk14, Crk1, Csbp1, Csbp2
Domain Architecture
Description	Mitogen-activated protein kinase 14 (EC 2.7.11.24) (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (CRK1).

MP2K1_HUMAN
NC score	0.690922 (rank : 388)	θ value	9.92553e-07 (rank : 877)
Query Neighborhood Hits	2923	Target Neighborhood Hits	826	Shared Neighborhood Hits	776
SwissProt Accessions	Q02750	Gene names	MAP2K1, MEK1, PRKMK1
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 1 (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1).

MK14_HUMAN
NC score	0.690913 (rank : 389)	θ value	1.09485e-13 (rank : 476)
Query Neighborhood Hits	2923	Target Neighborhood Hits	838	Shared Neighborhood Hits	780
SwissProt Accessions	Q16539, O60776, Q13083, Q14084, Q8TDX0	Gene names	MAPK14, CSBP, CSBP1, CSBP2, MXI2
Domain Architecture
Description	Mitogen-activated protein kinase 14 (EC 2.7.11.24) (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Cytokine suppressive anti-inflammatory drug-binding protein) (CSAID-binding protein) (CSBP) (MAX-interacting protein 2) (MAP kinase MXI2) (SAPK2A).

CCRK_MOUSE
NC score	0.690837 (rank : 390)	θ value	6.00763e-12 (rank : 547)
Query Neighborhood Hits	2923	Target Neighborhood Hits	832	Shared Neighborhood Hits	773
SwissProt Accessions	Q9JHU3, Q5EDC2	Gene names	Ccrk, Cdch
Domain Architecture	No domain graphic available
Description	Cell cycle-related kinase (EC 2.7.11.22) (Cyclin-kinase-activating kinase p42) (CDK-activating kinase p42) (CAK-kinase p42) (CDK-related protein kinase PNQLARE) (Cyclin-dependent protein kinase H).

MP2K1_MOUSE
NC score	0.690780 (rank : 391)	θ value	9.92553e-07 (rank : 878)
Query Neighborhood Hits	2923	Target Neighborhood Hits	826	Shared Neighborhood Hits	776
SwissProt Accessions	P31938	Gene names	Map2k1, Mek1, Prkmk1
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 1 (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1).

MK13_MOUSE
NC score	0.690649 (rank : 392)	θ value	1.58096e-12 (rank : 519)
Query Neighborhood Hits	2923	Target Neighborhood Hits	832	Shared Neighborhood Hits	778
SwissProt Accessions	Q9Z1B7, Q99M57	Gene names	Mapk13, Serk4
Domain Architecture
Description	Mitogen-activated protein kinase 13 (EC 2.7.11.24) (Stress-activated protein kinase 4) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta).

PMYT1_HUMAN
NC score	0.690525 (rank : 393)	θ value	5.26297e-08 (rank : 777)
Query Neighborhood Hits	2923	Target Neighborhood Hits	814	Shared Neighborhood Hits	759
SwissProt Accessions	Q99640, O14731, Q7LE24, Q8TCM9	Gene names	PKMYT1, MYT1
Domain Architecture	No domain graphic available
Description	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase).

KPCG_MOUSE
NC score	0.690519 (rank : 394)	θ value	2.97466e-19 (rank : 287)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1123	Shared Neighborhood Hits	795
SwissProt Accessions	P63318, P05697	Gene names	Prkcg, Pkcc, Pkcg, Prkcc
Domain Architecture	No domain graphic available
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

MK04_HUMAN
NC score	0.690356 (rank : 395)	θ value	1.9326e-10 (rank : 635)
Query Neighborhood Hits	2923	Target Neighborhood Hits	837	Shared Neighborhood Hits	780
SwissProt Accessions	P31152	Gene names	MAPK4, ERK4, PRKM4
Domain Architecture
Description	Mitogen-activated protein kinase 4 (EC 2.7.11.24) (Extracellular signal-regulated kinase 4) (ERK-4) (MAP kinase isoform p63) (p63- MAPK).

KPCG_HUMAN
NC score	0.690288 (rank : 396)	θ value	3.88503e-19 (rank : 290)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1126	Shared Neighborhood Hits	797
SwissProt Accessions	P05129	Gene names	PRKCG, PKCG
Domain Architecture
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

PCTK3_HUMAN
NC score	0.690284 (rank : 397)	θ value	1.29331e-14 (rank : 429)
Query Neighborhood Hits	2923	Target Neighborhood Hits	827	Shared Neighborhood Hits	769
SwissProt Accessions	Q07002, Q5VXQ2, Q96F90	Gene names	PCTK3
Domain Architecture
Description	Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22) (PCTAIRE- motif protein kinase 3).

STK16_HUMAN
NC score	0.690277 (rank : 398)	θ value	6.87365e-08 (rank : 788)
Query Neighborhood Hits	2923	Target Neighborhood Hits	824	Shared Neighborhood Hits	778
SwissProt Accessions	O75716, Q96KI2, Q9UEN3, Q9UP78	Gene names	STK16, MPSK1, PKL12, TSF1
Domain Architecture
Description	Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Protein kinase PKL12) (Myristoylated and palmitoylated serine/threonine-protein kinase) (MPSK) (TGF-beta-stimulated factor 1) (TSF-1) (hPSK).

PCTK2_HUMAN
NC score	0.689894 (rank : 399)	θ value	8.38298e-14 (rank : 468)
Query Neighborhood Hits	2923	Target Neighborhood Hits	837	Shared Neighborhood Hits	777
SwissProt Accessions	Q00537, Q8NEB8	Gene names	PCTK2
Domain Architecture
Description	Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22) (PCTAIRE- motif protein kinase 2).

CSK22_MOUSE
NC score	0.689735 (rank : 400)	θ value	3.07829e-16 (rank : 369)
Query Neighborhood Hits	2923	Target Neighborhood Hits	758	Shared Neighborhood Hits	730
SwissProt Accessions	O54833	Gene names	Csnk2a2
Domain Architecture
Description	Casein kinase II subunit alpha' (EC 2.7.11.1) (CK II).

CSK22_HUMAN
NC score	0.689700 (rank : 401)	θ value	2.35696e-16 (rank : 365)
Query Neighborhood Hits	2923	Target Neighborhood Hits	758	Shared Neighborhood Hits	730
SwissProt Accessions	P19784	Gene names	CSNK2A2, CK2A2
Domain Architecture
Description	Casein kinase II subunit alpha' (EC 2.7.11.1) (CK II).

MP2K2_MOUSE
NC score	0.689685 (rank : 402)	θ value	7.59969e-07 (rank : 870)
Query Neighborhood Hits	2923	Target Neighborhood Hits	828	Shared Neighborhood Hits	775
SwissProt Accessions	Q63932	Gene names	Map2k2, Mek2, Mkk2, Prkmk2
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 2 (EC 2.7.12.2) (MAP kinase kinase 2) (MAPKK 2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK2).

LATS1_HUMAN
NC score	0.689633 (rank : 403)	θ value	2.69671e-12 (rank : 535)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1057	Shared Neighborhood Hits	895
SwissProt Accessions	O95835, Q6PKD0	Gene names	LATS1, WARTS
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts).

MK13_HUMAN
NC score	0.689596 (rank : 404)	θ value	7.09661e-13 (rank : 500)
Query Neighborhood Hits	2923	Target Neighborhood Hits	829	Shared Neighborhood Hits	776
SwissProt Accessions	O15264, O14739, O15124, Q9UNU0	Gene names	MAPK13, PRKM13, SAPK4
Domain Architecture
Description	Mitogen-activated protein kinase 13 (EC 2.7.11.24) (Stress-activated protein kinase 4) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta).

PCTK2_MOUSE
NC score	0.689529 (rank : 405)	θ value	8.38298e-14 (rank : 469)
Query Neighborhood Hits	2923	Target Neighborhood Hits	836	Shared Neighborhood Hits	776
SwissProt Accessions	Q8K0D0	Gene names	Pctk2
Domain Architecture
Description	Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22) (PCTAIRE- motif protein kinase 2).

MK07_MOUSE
NC score	0.689142 (rank : 406)	θ value	6.64225e-11 (rank : 606)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1054	Shared Neighborhood Hits	890
SwissProt Accessions	Q9WVS8	Gene names	Mapk7, Erk5
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase).

MP2K5_HUMAN
NC score	0.688925 (rank : 407)	θ value	2.13673e-09 (rank : 697)
Query Neighborhood Hits	2923	Target Neighborhood Hits	837	Shared Neighborhood Hits	776
SwissProt Accessions	Q13163	Gene names	MAP2K5, MEK5, MKK5, PRKMK5
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 5 (EC 2.7.12.2) (MAP kinase kinase 5) (MAPKK 5) (MAPK/ERK kinase 5).

MK04_MOUSE
NC score	0.688669 (rank : 408)	θ value	9.59137e-10 (rank : 665)
Query Neighborhood Hits	2923	Target Neighborhood Hits	852	Shared Neighborhood Hits	778
SwissProt Accessions	Q6P5G0	Gene names	Mapk4, Erk4, Prkm4
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 4 (EC 2.7.11.24) (Extracellular signal-regulated kinase 4) (ERK-4).

HIPK4_HUMAN
NC score	0.688661 (rank : 409)	θ value	7.34386e-10 (rank : 660)
Query Neighborhood Hits	2923	Target Neighborhood Hits	799	Shared Neighborhood Hits	760
SwissProt Accessions	Q8NE63	Gene names	HIPK4
Domain Architecture	No domain graphic available
Description	Homeodomain-interacting protein kinase 4 (EC 2.7.11.1).

CD2L5_MOUSE
NC score	0.688603 (rank : 410)	θ value	6.00763e-12 (rank : 548)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1011	Shared Neighborhood Hits	857
SwissProt Accessions	Q69ZA1, Q80V11, Q8BZG1, Q8K0A4	Gene names	Cdc2l5, Kiaa1791
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5).

MK07_HUMAN
NC score	0.688368 (rank : 411)	θ value	6.64225e-11 (rank : 605)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1087	Shared Neighborhood Hits	898
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

STK16_MOUSE
NC score	0.688142 (rank : 412)	θ value	5.26297e-08 (rank : 780)
Query Neighborhood Hits	2923	Target Neighborhood Hits	824	Shared Neighborhood Hits	775
SwissProt Accessions	O88697, Q9JMJ0, Q9JMJ1, Q9QX00	Gene names	Stk16, Edpk, Krct, Mpsk1, Pkl12, Tsf1
Domain Architecture
Description	Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Protein kinase PKL12) (Myristoylated and palmitoylated serine/threonine-protein kinase) (MPSK) (TGF-beta-stimulated factor 1) (TSF-1) (Protein kinase Krct).

MK09_HUMAN
NC score	0.687769 (rank : 413)	θ value	1.133e-10 (rank : 623)
Query Neighborhood Hits	2923	Target Neighborhood Hits	842	Shared Neighborhood Hits	786
SwissProt Accessions	P45984, Q15708, Q15710, Q15711, Q8N5C5	Gene names	MAPK9, JNK2, PRKM9
Domain Architecture
Description	Mitogen-activated protein kinase 9 (EC 2.7.11.24) (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2) (JNK-55).

F5006_HUMAN
NC score	0.687667 (rank : 414)	θ value	0.00020696 (rank : 1032)
Query Neighborhood Hits	2923	Target Neighborhood Hits	794	Shared Neighborhood Hits	749
SwissProt Accessions	Q96LW2, Q49A48	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase FLJ25006 (EC 2.7.11.1).

CD2L5_HUMAN
NC score	0.687613 (rank : 415)	θ value	1.58096e-12 (rank : 511)
Query Neighborhood Hits	2923	Target Neighborhood Hits	987	Shared Neighborhood Hits	829
SwissProt Accessions	Q14004, Q6DKQ9, Q75MH4, Q75MH5, Q96JN4, Q9H4A0, Q9H4A1, Q9UDR4	Gene names	CDC2L5, CDC2L, CHED, KIAA1791
Domain Architecture
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5) (Cholinesterase-related cell division controller).

FGFR2_HUMAN
NC score	0.687328 (rank : 416)	θ value	2.69671e-12 (rank : 534)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1062	Shared Neighborhood Hits	993
SwissProt Accessions	P21802, P18443, Q01742, Q12922, Q14300, Q14301, Q14302, Q14303, Q14304, Q14305, Q14672, Q14718, Q14719, Q86YI4, Q96KL9, Q96KM0, Q96KM1, Q96KM2, Q9NZU2, Q9NZU3, Q9UD01, Q9UD02, Q9UIH3, Q9UIH4, Q9UIH5, Q9UIH6, Q9UIH7, Q9UIH8, Q9UM87, Q9UMC6, Q9UNS7, Q9UQH7, Q9UQH8, Q9UQH9, Q9UQI0	Gene names	FGFR2, BEK, KSAM
Domain Architecture
Description	Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor 2) (CD332 antigen).

MP2K7_HUMAN
NC score	0.687144 (rank : 417)	θ value	2.44474e-05 (rank : 957)
Query Neighborhood Hits	2923	Target Neighborhood Hits	833	Shared Neighborhood Hits	776
SwissProt Accessions	O14733, O14648, O14816, O60452, O60453	Gene names	MAP2K7, JNKK2, MKK7, PRKMK7
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 7 (EC 2.7.12.2) (MAP kinase kinase 7) (MAPKK 7) (MAPK/ERK kinase 7) (JNK-activating kinase 2) (c-Jun N-terminal kinase kinase 2) (JNK kinase 2) (JNKK 2).

LATS1_MOUSE
NC score	0.686986 (rank : 418)	θ value	5.08577e-11 (rank : 596)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1027	Shared Neighborhood Hits	883
SwissProt Accessions	Q8BYR2, Q9Z0W4	Gene names	Lats1, Warts
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase).

MK11_MOUSE
NC score	0.686627 (rank : 419)	θ value	3.89403e-11 (rank : 590)
Query Neighborhood Hits	2923	Target Neighborhood Hits	835	Shared Neighborhood Hits	783
SwissProt Accessions	Q9WUI1	Gene names	Mapk11, Prkm11
Domain Architecture
Description	Mitogen-activated protein kinase 11 (EC 2.7.11.24) (Mitogen-activated protein kinase p38 beta) (MAP kinase p38 beta) (p38B).

DYRK3_HUMAN
NC score	0.686463 (rank : 420)	θ value	1.058e-16 (rank : 356)
Query Neighborhood Hits	2923	Target Neighborhood Hits	798	Shared Neighborhood Hits	759
SwissProt Accessions	O43781	Gene names	DYRK3
Domain Architecture
Description	Dual specificity tyrosine-phosphorylation-regulated kinase 3 (EC 2.7.12.1).

FGFR3_MOUSE
NC score	0.686343 (rank : 421)	θ value	3.18553e-13 (rank : 491)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1059	Shared Neighborhood Hits	994
SwissProt Accessions	Q61851, Q61564, Q63834	Gene names	Fgfr3, Mfr3, Sam3
Domain Architecture
Description	Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1) (FGFR-3) (Heparin-binding growth factor receptor) (CD333 antigen).

MK03_MOUSE
NC score	0.685749 (rank : 422)	θ value	1.68911e-14 (rank : 435)
Query Neighborhood Hits	2923	Target Neighborhood Hits	840	Shared Neighborhood Hits	780
SwissProt Accessions	Q63844, Q61531, Q8K0X5, Q91YW5	Gene names	Mapk3, Erk1, Prkm3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 3 (EC 2.7.11.24) (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase 1) (MAPK 1) (p44-ERK1) (ERT2) (p44-MAPK) (Microtubule- associated protein 2 kinase) (MNK1).

DAPK1_HUMAN
NC score	0.685735 (rank : 423)	θ value	1.84601e-53 (rank : 33)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1130	Shared Neighborhood Hits	827
SwissProt Accessions	P53355, Q9BTL8	Gene names	DAPK1, DAPK
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

MK03_HUMAN
NC score	0.685535 (rank : 424)	θ value	1.68911e-14 (rank : 434)
Query Neighborhood Hits	2923	Target Neighborhood Hits	837	Shared Neighborhood Hits	778
SwissProt Accessions	P27361	Gene names	MAPK3, ERK1, PRKM3
Domain Architecture
Description	Mitogen-activated protein kinase 3 (EC 2.7.11.24) (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase 1) (MAPK 1) (p44-ERK1) (ERT2) (p44-MAPK) (Microtubule- associated protein 2 kinase).

LATS2_HUMAN
NC score	0.685491 (rank : 425)	θ value	4.59992e-12 (rank : 543)
Query Neighborhood Hits	2923	Target Neighborhood Hits	884	Shared Neighborhood Hits	800
SwissProt Accessions	Q9NRM7, Q9P2X1	Gene names	LATS2, KPM
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein) (Warts-like kinase).

CDK4_MOUSE
NC score	0.685346 (rank : 426)	θ value	1.53129e-07 (rank : 816)
Query Neighborhood Hits	2923	Target Neighborhood Hits	838	Shared Neighborhood Hits	781
SwissProt Accessions	P30285	Gene names	Cdk4, Crk3
Domain Architecture
Description	Cell division protein kinase 4 (EC 2.7.11.22) (Cyclin-dependent kinase 4) (PSK-J3) (CRK3).

MK01_HUMAN
NC score	0.684990 (rank : 427)	θ value	6.41864e-14 (rank : 457)
Query Neighborhood Hits	2923	Target Neighborhood Hits	836	Shared Neighborhood Hits	779
SwissProt Accessions	P28482	Gene names	MAPK1, ERK2, PRKM1
Domain Architecture
Description	Mitogen-activated protein kinase 1 (EC 2.7.11.24) (Extracellular signal-regulated kinase 2) (ERK-2) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2) (p42-MAPK) (ERT1).

MK01_MOUSE
NC score	0.684823 (rank : 428)	θ value	6.41864e-14 (rank : 458)
Query Neighborhood Hits	2923	Target Neighborhood Hits	836	Shared Neighborhood Hits	779
SwissProt Accessions	P63085, P27703, Q3V1U6	Gene names	Mapk1, Erk2, Mapk, Prkm1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 1 (EC 2.7.11.24) (Extracellular signal-regulated kinase 2) (ERK-2) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2) (p42-MAPK) (ERT1).

TNIK_HUMAN
NC score	0.684820 (rank : 429)	θ value	5.8054e-15 (rank : 417)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1570	Shared Neighborhood Hits	1095
SwissProt Accessions	Q9UKE5, O60298, Q8WUY7, Q9UKD8, Q9UKD9, Q9UKE0, Q9UKE1, Q9UKE2, Q9UKE3, Q9UKE4	Gene names	TNIK, KIAA0551
Domain Architecture
Description	TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1).

LATS2_MOUSE
NC score	0.684767 (rank : 430)	θ value	1.02475e-11 (rank : 566)
Query Neighborhood Hits	2923	Target Neighborhood Hits	879	Shared Neighborhood Hits	790
SwissProt Accessions	Q7TSJ6, Q8CDJ4, Q9JMI3	Gene names	Lats2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein).

AL2S7_HUMAN
NC score	0.684606 (rank : 431)	θ value	1.63604e-09 (rank : 677)
Query Neighborhood Hits	2923	Target Neighborhood Hits	831	Shared Neighborhood Hits	775
SwissProt Accessions	Q96Q40, Q4ZG86, Q53TV1	Gene names	ALS2CR7
Domain Architecture
Description	Serine/threonine-protein kinase ALS2CR7 (EC 2.7.11.22) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein).

MK08_MOUSE
NC score	0.684485 (rank : 432)	θ value	6.00763e-12 (rank : 554)
Query Neighborhood Hits	2923	Target Neighborhood Hits	834	Shared Neighborhood Hits	777
SwissProt Accessions	Q91Y86	Gene names	Mapk8, Jnk1, Prkm8
Domain Architecture
Description	Mitogen-activated protein kinase 8 (EC 2.7.11.24) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1).

CDK4_HUMAN
NC score	0.684398 (rank : 433)	θ value	2.61198e-07 (rank : 829)
Query Neighborhood Hits	2923	Target Neighborhood Hits	834	Shared Neighborhood Hits	779
SwissProt Accessions	P11802, O00576	Gene names	CDK4
Domain Architecture
Description	Cell division protein kinase 4 (EC 2.7.11.22) (Cyclin-dependent kinase 4) (PSK-J3).

MK09_MOUSE
NC score	0.684278 (rank : 434)	θ value	9.59137e-10 (rank : 666)
Query Neighborhood Hits	2923	Target Neighborhood Hits	843	Shared Neighborhood Hits	785
SwissProt Accessions	Q9WTU6, Q8C097, Q8VDD2, Q9WTU4, Q9WTU5	Gene names	Mapk9, Jnk2, Prkm9
Domain Architecture
Description	Mitogen-activated protein kinase 9 (EC 2.7.11.24) (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2).

M4K5_MOUSE
NC score	0.684271 (rank : 435)	θ value	5.08577e-11 (rank : 597)
Query Neighborhood Hits	2923	Target Neighborhood Hits	839	Shared Neighborhood Hits	774
SwissProt Accessions	Q8BPM2, Q6PEQ2, Q8C3U5, Q8CGF3, Q99LM7, Q9CX73	Gene names	Map4k5
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 5) (MEK kinase kinase 5) (MEKKK 5).

NLK_MOUSE
NC score	0.683976 (rank : 436)	θ value	2.98157e-11 (rank : 587)
Query Neighborhood Hits	2923	Target Neighborhood Hits	839	Shared Neighborhood Hits	780
SwissProt Accessions	O54949, Q6PF98	Gene names	Nlk
Domain Architecture	No domain graphic available
Description	Serine/threonine kinase NLK (EC 2.7.11.24) (Nemo-like kinase).

MK08_HUMAN
NC score	0.683955 (rank : 437)	θ value	6.00763e-12 (rank : 553)
Query Neighborhood Hits	2923	Target Neighborhood Hits	834	Shared Neighborhood Hits	777
SwissProt Accessions	P45983, Q15709, Q15712, Q15713	Gene names	MAPK8, JNK1, PRKM8
Domain Architecture
Description	Mitogen-activated protein kinase 8 (EC 2.7.11.24) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1) (JNK-46).

NLK_HUMAN
NC score	0.683897 (rank : 438)	θ value	2.98157e-11 (rank : 586)
Query Neighborhood Hits	2923	Target Neighborhood Hits	840	Shared Neighborhood Hits	780
SwissProt Accessions	Q9UBE8, Q2PNI9, Q6P2A3	Gene names	NLK, LAK1
Domain Architecture	No domain graphic available
Description	Serine/threonine kinase NLK (EC 2.7.11.24) (Nemo-like kinase) (Protein LAK1).

M4K5_HUMAN
NC score	0.683595 (rank : 439)	θ value	2.98157e-11 (rank : 584)
Query Neighborhood Hits	2923	Target Neighborhood Hits	845	Shared Neighborhood Hits	778
SwissProt Accessions	Q9Y4K4, Q8IYF6	Gene names	MAP4K5
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 5) (MEK kinase kinase 5) (MEKKK 5) (Kinase homologous to SPS1/STE20) (KHS).

MP2K4_HUMAN
NC score	0.683556 (rank : 440)	θ value	5.26297e-08 (rank : 775)
Query Neighborhood Hits	2923	Target Neighborhood Hits	832	Shared Neighborhood Hits	780
SwissProt Accessions	P45985, Q5U0B8	Gene names	MAP2K4, JNKK1, MKK4, PRKMK4, SERK1
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 4 (EC 2.7.12.2) (MAP kinase kinase 4) (JNK-activating kinase 1) (c-Jun N-terminal kinase kinase 1) (JNKK) (SAPK/ERK kinase 1) (SEK1).

MP2K4_MOUSE
NC score	0.683514 (rank : 441)	θ value	5.26297e-08 (rank : 776)
Query Neighborhood Hits	2923	Target Neighborhood Hits	833	Shared Neighborhood Hits	780
SwissProt Accessions	P47809	Gene names	Map2k4, Jnkk1, Prkmk4, Sek1, Serk1
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 4 (EC 2.7.12.2) (MAP kinase kinase 4) (MAPKK 4) (MAPK/ERK kinase 4) (JNK-activating kinase 1) (C-JUN N-terminal kinase kinase 1) (JNK kinase 1) (JNKK 1) (SAPK/ERK kinase 1) (SEK1).

MINK1_HUMAN
NC score	0.683314 (rank : 442)	θ value	1.86753e-13 (rank : 481)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1477	Shared Neighborhood Hits	1083
SwissProt Accessions	Q8N4C8, Q9P1X1, Q9P2R8	Gene names	MINK1, MAP4K6, MINK
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

DYRK2_HUMAN
NC score	0.683150 (rank : 443)	θ value	5.8054e-15 (rank : 412)
Query Neighborhood Hits	2923	Target Neighborhood Hits	799	Shared Neighborhood Hits	751
SwissProt Accessions	Q92630	Gene names	DYRK2
Domain Architecture
Description	Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1).

MINK1_MOUSE
NC score	0.682859 (rank : 444)	θ value	3.18553e-13 (rank : 493)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1451	Shared Neighborhood Hits	1066
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

STK10_HUMAN
NC score	0.682644 (rank : 445)	θ value	6.00763e-12 (rank : 555)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1921	Shared Neighborhood Hits	1213
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

VGFR2_HUMAN
NC score	0.682557 (rank : 446)	θ value	5.42112e-21 (rank : 246)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1103	Shared Neighborhood Hits	1019
SwissProt Accessions	P35968, O60723, Q14178	Gene names	KDR, FLK1
Domain Architecture
Description	Vascular endothelial growth factor receptor 2 precursor (EC 2.7.10.1) (VEGFR-2) (Kinase insert domain receptor) (Protein-tyrosine kinase receptor Flk-1) (CD309 antigen).

FGFR2_MOUSE
NC score	0.682515 (rank : 447)	θ value	6.00763e-12 (rank : 551)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1062	Shared Neighborhood Hits	992
SwissProt Accessions	P21803, O55141, Q00389, Q61342	Gene names	Fgfr2, Bek, Ect1
Domain Architecture
Description	Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor) (CD332 antigen).

NRK_HUMAN
NC score	0.682498 (rank : 448)	θ value	1.06045e-08 (rank : 743)
Query Neighborhood Hits	2923	Target Neighborhood Hits	931	Shared Neighborhood Hits	818
SwissProt Accessions	Q7Z2Y5, Q32ND6, Q5H9K2, Q6ZMP2	Gene names	NRK
Domain Architecture	No domain graphic available
Description	Nik-related protein kinase (EC 2.7.11.1).

FGFR3_HUMAN
NC score	0.682476 (rank : 449)	θ value	1.02475e-11 (rank : 564)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1042	Shared Neighborhood Hits	979
SwissProt Accessions	P22607, Q14308, Q16294, Q16608	Gene names	FGFR3, JTK4
Domain Architecture
Description	Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1) (FGFR-3) (CD333 antigen).

DAPK1_MOUSE
NC score	0.682034 (rank : 450)	θ value	1.66964e-54 (rank : 28)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1138	Shared Neighborhood Hits	827
SwissProt Accessions	Q80YE7, Q80YE6, Q8R341, Q8VDN6, Q9CSD4, Q9JJP7	Gene names	Dapk1
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

MK10_HUMAN
NC score	0.681977 (rank : 451)	θ value	1.133e-10 (rank : 624)
Query Neighborhood Hits	2923	Target Neighborhood Hits	836	Shared Neighborhood Hits	776
SwissProt Accessions	P53779, Q15707	Gene names	MAPK10, JNK3, JNK3A, PRKM10
Domain Architecture
Description	Mitogen-activated protein kinase 10 (EC 2.7.11.24) (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3) (MAP kinase p49 3F12).

MK11_HUMAN
NC score	0.681832 (rank : 452)	θ value	3.29651e-10 (rank : 644)
Query Neighborhood Hits	2923	Target Neighborhood Hits	823	Shared Neighborhood Hits	776
SwissProt Accessions	Q15759, O00284, O15472, Q2XNF2	Gene names	MAPK11, PRKM11, SAPK2
Domain Architecture
Description	Mitogen-activated protein kinase 11 (EC 2.7.11.24) (Mitogen-activated protein kinase p38 beta) (MAP kinase p38 beta) (p38b) (p38-2) (Stress- activated protein kinase 2).

DYR1B_MOUSE
NC score	0.681592 (rank : 453)	θ value	9.90251e-15 (rank : 423)
Query Neighborhood Hits	2923	Target Neighborhood Hits	799	Shared Neighborhood Hits	763
SwissProt Accessions	Q9Z188	Gene names	Dyrk1b
Domain Architecture
Description	Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1).

VGFR2_MOUSE
NC score	0.681338 (rank : 454)	θ value	1.38178e-16 (rank : 362)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1089	Shared Neighborhood Hits	1010
SwissProt Accessions	P35918	Gene names	Kdr, Flk-1, Flk1
Domain Architecture
Description	Vascular endothelial growth factor receptor 2 precursor (EC 2.7.10.1) (VEGFR-2) (Protein-tyrosine kinase receptor flk-1) (Fetal liver kinase 1) (Kinase NYK) (CD309 antigen).

MK10_MOUSE
NC score	0.681285 (rank : 455)	θ value	1.9326e-10 (rank : 636)
Query Neighborhood Hits	2923	Target Neighborhood Hits	849	Shared Neighborhood Hits	780
SwissProt Accessions	Q61831, Q9R0U6	Gene names	Mapk10, Jnk3, Prkm10, Serk2
Domain Architecture
Description	Mitogen-activated protein kinase 10 (EC 2.7.11.24) (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3) (MAP kinase p49 3F12).

FGFR4_HUMAN
NC score	0.680929 (rank : 456)	θ value	1.33837e-11 (rank : 569)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1037	Shared Neighborhood Hits	976
SwissProt Accessions	P22455, O43785, Q14309	Gene names	FGFR4, JTK2, TKF
Domain Architecture
Description	Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1) (FGFR-4) (CD334 antigen).

MK06_HUMAN
NC score	0.680582 (rank : 457)	θ value	2.69671e-12 (rank : 537)
Query Neighborhood Hits	2923	Target Neighborhood Hits	815	Shared Neighborhood Hits	769
SwissProt Accessions	Q16659, Q68DH4, Q8IYN8	Gene names	MAPK6, ERK3, PRKM6
Domain Architecture
Description	Mitogen-activated protein kinase 6 (EC 2.7.11.24) (Extracellular signal-regulated kinase 3) (ERK-3) (MAP kinase isoform p97) (p97- MAPK).

ERN1_MOUSE
NC score	0.680441 (rank : 458)	θ value	1.29631e-06 (rank : 884)
Query Neighborhood Hits	2923	Target Neighborhood Hits	823	Shared Neighborhood Hits	766
SwissProt Accessions	Q9EQY0, Q9D340	Gene names	Ern1, Ire1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase/endoribonuclease IRE1 precursor (Inositol-requiring protein 1) (IRE1a) (Ire1-alpha) (Endoplasmic reticulum-to-nucleus signaling 1) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)].

NRK_MOUSE
NC score	0.680405 (rank : 459)	θ value	4.45536e-07 (rank : 852)
Query Neighborhood Hits	2923	Target Neighborhood Hits	899	Shared Neighborhood Hits	813
SwissProt Accessions	Q9R0G8, Q6NV55, Q8C9S9, Q9R0S4	Gene names	Nrk, Nesk
Domain Architecture	No domain graphic available
Description	Nik-related protein kinase (EC 2.7.11.1) (Nck-interacting kinase-like embryo specific kinase) (NIK-like embryo-specific kinase) (NESK).

TAOK2_HUMAN
NC score	0.680404 (rank : 460)	θ value	1.133e-10 (rank : 626)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1172	Shared Neighborhood Hits	954
SwissProt Accessions	Q9UL54, O94957, Q6UW73, Q7LC09, Q9NSW2	Gene names	TAOK2, KIAA0881, MAP3K17, PSK, PSK1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Thousand and one amino acid protein 2) (Prostate-derived STE20-like kinase 1) (PSK-1) (Kinase from chicken homolog C) (hKFC-C).

MK06_MOUSE
NC score	0.680376 (rank : 461)	θ value	2.0648e-12 (rank : 526)
Query Neighborhood Hits	2923	Target Neighborhood Hits	818	Shared Neighborhood Hits	772
SwissProt Accessions	Q61532, Q497T9, Q6YKB0, Q7TT30, Q80XH5, Q922U4, Q9JLU6	Gene names	Mapk6, Erk3, Prkm4, Prkm6
Domain Architecture
Description	Mitogen-activated protein kinase 6 (EC 2.7.11.24) (Extracellular signal-regulated kinase 3) (ERK-3).

ERN1_HUMAN
NC score	0.680216 (rank : 462)	θ value	6.43352e-06 (rank : 916)
Query Neighborhood Hits	2923	Target Neighborhood Hits	829	Shared Neighborhood Hits	772
SwissProt Accessions	O75460	Gene names	ERN1, IRE1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase/endoribonuclease IRE1 precursor (Inositol-requiring protein 1) (hIRE1p) (IRE1a) (Ire1-alpha) (Endoplasmic reticulum-to-nucleus signaling 1) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)].

MP2K3_MOUSE
NC score	0.678820 (rank : 463)	θ value	1.29631e-06 (rank : 888)
Query Neighborhood Hits	2923	Target Neighborhood Hits	826	Shared Neighborhood Hits	770
SwissProt Accessions	O09110, P97293, Q91VX1	Gene names	Map2k3, Mkk3, Prkmk3
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 3 (EC 2.7.12.2) (MAP kinase kinase 3) (MAPKK 3) (MAPK/ERK kinase 3).

MRCKG_MOUSE
NC score	0.678285 (rank : 464)	θ value	1.68911e-14 (rank : 436)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1466	Shared Neighborhood Hits	1038
SwissProt Accessions	Q80UW5	Gene names	Cdc42bpg
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

MRCKG_HUMAN
NC score	0.678168 (rank : 465)	θ value	4.91457e-14 (rank : 453)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1519	Shared Neighborhood Hits	1038
SwissProt Accessions	Q6DT37, O00565	Gene names	CDC42BPG
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

MP2K3_HUMAN
NC score	0.677691 (rank : 466)	θ value	3.77169e-06 (rank : 909)
Query Neighborhood Hits	2923	Target Neighborhood Hits	825	Shared Neighborhood Hits	769
SwissProt Accessions	P46734, Q99441, Q9UE71, Q9UE72	Gene names	MAP2K3, MEK3, MKK3, PRKMK3
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 3 (EC 2.7.12.2) (MAP kinase kinase 3) (MAPKK 3) (MAPK/ERK kinase 3).

DYR1B_HUMAN
NC score	0.677678 (rank : 467)	θ value	2.20605e-14 (rank : 437)
Query Neighborhood Hits	2923	Target Neighborhood Hits	831	Shared Neighborhood Hits	774
SwissProt Accessions	Q9Y463, O75258, O75788, O75789	Gene names	DYRK1B, MIRK
Domain Architecture
Description	Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1) (Mirk protein kinase) (Minibrain-related kinase).

CDK10_HUMAN
NC score	0.677495 (rank : 468)	θ value	5.08577e-11 (rank : 593)
Query Neighborhood Hits	2923	Target Neighborhood Hits	831	Shared Neighborhood Hits	779
SwissProt Accessions	Q15131, Q15130	Gene names	CDK10
Domain Architecture
Description	Cell division protein kinase 10 (EC 2.7.11.22) (Serine/threonine- protein kinase PISSLRE).

DYRK4_HUMAN
NC score	0.677278 (rank : 469)	θ value	5.07402e-19 (rank : 294)
Query Neighborhood Hits	2923	Target Neighborhood Hits	750	Shared Neighborhood Hits	733
SwissProt Accessions	Q9NR20, Q8NEF2, Q92631	Gene names	DYRK4
Domain Architecture	No domain graphic available
Description	Dual specificity tyrosine-phosphorylation-regulated kinase 4 (EC 2.7.12.1).

CD2L2_HUMAN
NC score	0.675473 (rank : 470)	θ value	1.17247e-07 (rank : 800)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1439	Shared Neighborhood Hits	1056
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

HIPK3_MOUSE
NC score	0.675390 (rank : 471)	θ value	6.64225e-11 (rank : 603)
Query Neighborhood Hits	2923	Target Neighborhood Hits	857	Shared Neighborhood Hits	773
SwissProt Accessions	Q9ERH7, O88906, Q9QZR2	Gene names	Hipk3, Fist3
Domain Architecture	No domain graphic available
Description	Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Fas- interacting serine/threonine-protein kinase) (FIST) (Nuclear body- associated kinase 3) (Nbak3) (Androgen receptor-interacting nuclear protein kinase) (ANPK).

UHMK1_HUMAN
NC score	0.675376 (rank : 472)	θ value	2.88788e-06 (rank : 902)
Query Neighborhood Hits	2923	Target Neighborhood Hits	808	Shared Neighborhood Hits	746
SwissProt Accessions	Q8TAS1, Q96C22	Gene names	UHMK1, KIS, KIST
Domain Architecture
Description	Serine/threonine-protein kinase Kist (EC 2.7.11.1) (Kinase interacting with stathmin) (U2AF homology motif kinase 1).

MP2K6_MOUSE
NC score	0.675361 (rank : 473)	θ value	6.87365e-08 (rank : 787)
Query Neighborhood Hits	2923	Target Neighborhood Hits	830	Shared Neighborhood Hits	771
SwissProt Accessions	P70236	Gene names	Map2k6, Prkmk6, Sapkk3
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 6 (EC 2.7.12.2) (MAP kinase kinase 6) (MAPKK 6) (MAPK/ERK kinase 6) (SAPKK3).

TAOK2_MOUSE
NC score	0.674737 (rank : 474)	θ value	1.47974e-10 (rank : 630)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1373	Shared Neighborhood Hits	1042
SwissProt Accessions	Q6ZQ29, Q7TSS8	Gene names	Taok2, Kiaa0881
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Thousand and one amino acid protein 2).

CDK9_HUMAN
NC score	0.674678 (rank : 475)	θ value	9.92553e-07 (rank : 874)
Query Neighborhood Hits	2923	Target Neighborhood Hits	822	Shared Neighborhood Hits	766
SwissProt Accessions	P50750, Q5JU24, Q5JU25, Q5U006, Q96TF1	Gene names	CDK9, CDC2L4
Domain Architecture
Description	Cell division protein kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (Cyclin- dependent kinase 9) (Serine/threonine-protein kinase PITALRE) (C-2K) (Cell division cycle 2-like protein kinase 4).

M4K4_HUMAN
NC score	0.674672 (rank : 476)	θ value	1.58096e-12 (rank : 516)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1589	Shared Neighborhood Hits	1100
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

CD2L1_MOUSE
NC score	0.674546 (rank : 477)	θ value	1.53129e-07 (rank : 815)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1463	Shared Neighborhood Hits	1052
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

CD2L1_HUMAN
NC score	0.674472 (rank : 478)	θ value	1.53129e-07 (rank : 814)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1467	Shared Neighborhood Hits	1054
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

UHMK1_MOUSE
NC score	0.674260 (rank : 479)	θ value	4.92598e-06 (rank : 915)
Query Neighborhood Hits	2923	Target Neighborhood Hits	809	Shared Neighborhood Hits	747
SwissProt Accessions	P97343, Q61775, Q9CYT1	Gene names	Uhmk1, Kis, Kist
Domain Architecture
Description	Serine/threonine-protein kinase Kist (EC 2.7.11.1) (Kinase interacting with stathmin) (U2AF homology motif kinase 1).

MP2K6_HUMAN
NC score	0.674227 (rank : 480)	θ value	6.87365e-08 (rank : 786)
Query Neighborhood Hits	2923	Target Neighborhood Hits	830	Shared Neighborhood Hits	770
SwissProt Accessions	P52564	Gene names	MAP2K6, MEK6, MKK6, PRKMK6
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 6 (EC 2.7.12.2) (MAP kinase kinase 6) (MAPKK 6) (MAPK/ERK kinase 6) (SAPKK3).

HIPK1_HUMAN
NC score	0.674135 (rank : 481)	θ value	2.0648e-12 (rank : 524)
Query Neighborhood Hits	2923	Target Neighborhood Hits	843	Shared Neighborhood Hits	777
SwissProt Accessions	Q86Z02, O75125, Q8IYD7, Q8NDN5, Q8NEB6, Q8TBZ1	Gene names	HIPK1, KIAA0630
Domain Architecture
Description	Homeodomain-interacting protein kinase 1 (EC 2.7.11.1).

CDK9_MOUSE
NC score	0.674041 (rank : 482)	θ value	3.77169e-06 (rank : 906)
Query Neighborhood Hits	2923	Target Neighborhood Hits	822	Shared Neighborhood Hits	766
SwissProt Accessions	Q99J95, Q3U002, Q3UMY2, Q3UPT3, Q3UQI6, Q8BTN0	Gene names	Cdk9
Domain Architecture	No domain graphic available
Description	Cell division protein kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (Cyclin- dependent kinase 9).

HIPK1_MOUSE
NC score	0.673932 (rank : 483)	θ value	2.0648e-12 (rank : 525)
Query Neighborhood Hits	2923	Target Neighborhood Hits	838	Shared Neighborhood Hits	774
SwissProt Accessions	O88904, Q80TV5, Q9QUQ8, Q9QZR3, Q9WVN7	Gene names	Hipk1, Kiaa0630, Myak, Nbak2
Domain Architecture
Description	Homeodomain-interacting protein kinase 1 (EC 2.7.11.1) (Protein kinase Myak) (Nuclear body-associated kinase 2).

HIPK3_HUMAN
NC score	0.673732 (rank : 484)	θ value	5.08577e-11 (rank : 594)
Query Neighborhood Hits	2923	Target Neighborhood Hits	867	Shared Neighborhood Hits	772
SwissProt Accessions	Q9H422, O14632, Q2PBG4, Q2PBG5, Q92632, Q9HAS2	Gene names	HIPK3, DYRK6, FIST3, PKY
Domain Architecture	No domain graphic available
Description	Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Homolog of protein kinase YAK1) (Fas-interacting serine/threonine-protein kinase) (FIST) (Androgen receptor-interacting nuclear protein kinase) (ANPK).

HIPK2_HUMAN
NC score	0.673471 (rank : 485)	θ value	2.98157e-11 (rank : 580)
Query Neighborhood Hits	2923	Target Neighborhood Hits	845	Shared Neighborhood Hits	773
SwissProt Accessions	Q9H2X6, Q75MR7, Q8WWI4, Q9H2Y1	Gene names	HIPK2
Domain Architecture
Description	Homeodomain-interacting protein kinase 2 (EC 2.7.11.1) (hHIPk2).

E2AK3_HUMAN
NC score	0.673118 (rank : 486)	θ value	0.00035302 (rank : 1042)
Query Neighborhood Hits	2923	Target Neighborhood Hits	859	Shared Neighborhood Hits	785
SwissProt Accessions	Q9NZJ5, O95846	Gene names	EIF2AK3, PEK, PERK
Domain Architecture
Description	Eukaryotic translation initiation factor 2-alpha kinase 3 precursor (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase) (HsPEK).

HIPK2_MOUSE
NC score	0.672675 (rank : 487)	θ value	2.98157e-11 (rank : 581)
Query Neighborhood Hits	2923	Target Neighborhood Hits	871	Shared Neighborhood Hits	786
SwissProt Accessions	Q9QZR5, O88905, Q99P45, Q99P46, Q9D2E6, Q9D474, Q9EQL2, Q9QZR4	Gene names	Hipk2, Nbak1, Stank
Domain Architecture
Description	Homeodomain-interacting protein kinase 2 (EC 2.7.11.1) (Nuclear body- associated kinase 1) (Sialophorin tail-associated nuclear serine/threonine-protein kinase).

CI096_HUMAN
NC score	0.671975 (rank : 488)	θ value	0.00035302 (rank : 1041)
Query Neighborhood Hits	2923	Target Neighborhood Hits	821	Shared Neighborhood Hits	763
SwissProt Accessions	Q8NE28, Q5T8U8	Gene names	C9orf96
Domain Architecture	No domain graphic available
Description	Protein kinase-like protein C9orf96.

ERN2_HUMAN
NC score	0.671109 (rank : 489)	θ value	9.29e-05 (rank : 998)
Query Neighborhood Hits	2923	Target Neighborhood Hits	844	Shared Neighborhood Hits	778
SwissProt Accessions	Q76MJ5, Q6ZNC0	Gene names	ERN2, IRE2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase/endoribonuclease IRE2 precursor (Inositol-requiring protein 2) (hIRE2p) (IRE1b) (Ire1-beta) (Endoplasmic reticulum-to-nucleus signaling 2) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)].

TRIB2_HUMAN
NC score	0.670939 (rank : 490)	θ value	2.52405e-10 (rank : 639)
Query Neighborhood Hits	2923	Target Neighborhood Hits	657	Shared Neighborhood Hits	640
SwissProt Accessions	Q92519	Gene names	TRIB2, TRB2
Domain Architecture	No domain graphic available
Description	Tribbles homolog 2 (TRB-2).

TRIB2_MOUSE
NC score	0.670590 (rank : 491)	θ value	1.47974e-10 (rank : 631)
Query Neighborhood Hits	2923	Target Neighborhood Hits	653	Shared Neighborhood Hits	635
SwissProt Accessions	Q8K4K3, Q8K017, Q8R2V8	Gene names	Trib2
Domain Architecture	No domain graphic available
Description	Tribbles homolog 2 (TRB-2).

E2AK3_MOUSE
NC score	0.670069 (rank : 492)	θ value	0.000461057 (rank : 1052)
Query Neighborhood Hits	2923	Target Neighborhood Hits	851	Shared Neighborhood Hits	788
SwissProt Accessions	Q9Z2B5, Q9CTK8, Q9CWT5	Gene names	Eif2ak3, Pek, Perk
Domain Architecture
Description	Eukaryotic translation initiation factor 2-alpha kinase 3 precursor (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase).

M4K4_MOUSE
NC score	0.669713 (rank : 493)	θ value	6.64225e-11 (rank : 604)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1560	Shared Neighborhood Hits	1088
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

DYR1A_MOUSE
NC score	0.669628 (rank : 494)	θ value	8.38298e-14 (rank : 464)
Query Neighborhood Hits	2923	Target Neighborhood Hits	762	Shared Neighborhood Hits	739
SwissProt Accessions	Q61214	Gene names	Dyrk1a, Dyrk
Domain Architecture
Description	Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.1) (Protein kinase minibrain homolog) (MNBH) (MP86) (Dual specificity YAK1-related kinase).

DYR1A_HUMAN
NC score	0.669625 (rank : 495)	θ value	8.38298e-14 (rank : 463)
Query Neighborhood Hits	2923	Target Neighborhood Hits	764	Shared Neighborhood Hits	740
SwissProt Accessions	Q13627, O60769, Q92582, Q92810, Q9UNM5	Gene names	DYRK1A, DYRK, MNB, MNBH
Domain Architecture
Description	Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.1) (Protein kinase minibrain homolog) (MNBH) (HP86) (Dual specificity YAK1-related kinase).

CD2L6_MOUSE
NC score	0.668954 (rank : 496)	θ value	1.17247e-07 (rank : 802)
Query Neighborhood Hits	2923	Target Neighborhood Hits	851	Shared Neighborhood Hits	780
SwissProt Accessions	Q8BWD8, Q80TM1	Gene names	Cdc2l6, Kiaa1028
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 6 (EC 2.7.11.22) (CDC2- related protein kinase 6).

TAOK3_MOUSE
NC score	0.668895 (rank : 497)	θ value	8.67504e-11 (rank : 618)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1458	Shared Neighborhood Hits	1065
SwissProt Accessions	Q8BYC6, Q3V3B3	Gene names	Taok3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3).

CD2L6_HUMAN
NC score	0.668838 (rank : 498)	θ value	1.17247e-07 (rank : 801)
Query Neighborhood Hits	2923	Target Neighborhood Hits	844	Shared Neighborhood Hits	777
SwissProt Accessions	Q9BWU1, Q5JQZ7, Q5JR00, Q8TC78, Q9UPX2	Gene names	CDC2L6, CDK11, KIAA1028
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 6 (EC 2.7.11.22) (CDC2- related protein kinase 6) (Death-preventing kinase) (Cyclin-dependent kinase 11).

PRP4B_HUMAN
NC score	0.668737 (rank : 499)	θ value	1.63604e-09 (rank : 684)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1030	Shared Neighborhood Hits	883
SwissProt Accessions	Q13523, Q8TDP2, Q96QT7, Q9UEE6	Gene names	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (PRP4 kinase).

TAOK3_HUMAN
NC score	0.668450 (rank : 500)	θ value	3.89403e-11 (rank : 592)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1494	Shared Neighborhood Hits	1078
SwissProt Accessions	Q9H2K8, Q658N1, Q8IUM4, Q9HC79, Q9NZM9, Q9UHG7	Gene names	TAOK3, DPK, JIK, KDS, MAP3K18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3) (Jun kinase-inhibitory kinase) (JNK/SAPK- inhibitory kinase) (Dendritic cell-derived protein kinase) (Cutaneous T-cell lymphoma tumor antigen HD-CL-09) (CTCL tumor antigen HD-CL-09) (Kinase from chicken homolog A) (hKFC-A).

M3K13_HUMAN
NC score	0.668361 (rank : 501)	θ value	4.76016e-09 (rank : 721)
Query Neighborhood Hits	2923	Target Neighborhood Hits	911	Shared Neighborhood Hits	799
SwissProt Accessions	O43283	Gene names	MAP3K13, LZK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Mixed lineage kinase) (MLK) (Leucine zipper-bearing kinase).

STK10_MOUSE
NC score	0.667967 (rank : 502)	θ value	7.84624e-12 (rank : 561)
Query Neighborhood Hits	2923	Target Neighborhood Hits	2132	Shared Neighborhood Hits	1268
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

ERN2_MOUSE
NC score	0.667591 (rank : 503)	θ value	6.43352e-06 (rank : 917)
Query Neighborhood Hits	2923	Target Neighborhood Hits	825	Shared Neighborhood Hits	766
SwissProt Accessions	Q9Z2E3	Gene names	Ern2, Ire2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase/endoribonuclease IRE2 precursor (Inositol-requiring protein 2) (IRE1b) (Ire1-beta) (Endoplasmic reticulum-to-nucleus signaling 2) (mIre1) [Includes: Serine/threonine- protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)].

CLK1_HUMAN
NC score	0.667399 (rank : 504)	θ value	5.43371e-13 (rank : 496)
Query Neighborhood Hits	2923	Target Neighborhood Hits	756	Shared Neighborhood Hits	733
SwissProt Accessions	P49759	Gene names	CLK1, CLK
Domain Architecture
Description	Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1).

PRP4B_MOUSE
NC score	0.667377 (rank : 505)	θ value	1.63604e-09 (rank : 685)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1040	Shared Neighborhood Hits	884
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

E2AK1_MOUSE
NC score	0.667085 (rank : 506)	θ value	θ > 10 (rank : 2989)
Query Neighborhood Hits	2923	Target Neighborhood Hits	821	Shared Neighborhood Hits	766
SwissProt Accessions	Q9Z2R9, Q8C024, Q8K123, Q9CTP5, Q9D601	Gene names	Eif2ak1, Hri
Domain Architecture
Description	Eukaryotic translation initiation factor 2-alpha kinase 1 (EC 2.7.11.1) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Heme-controlled repressor) (HCR) (Hemin-sensitive initiation factor 2-alpha kinase).

CLK1_MOUSE
NC score	0.666851 (rank : 507)	θ value	2.0648e-12 (rank : 522)
Query Neighborhood Hits	2923	Target Neighborhood Hits	760	Shared Neighborhood Hits	737
SwissProt Accessions	P22518	Gene names	Clk1, Clk, Sty
Domain Architecture
Description	Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1) (Protein kinase STY).

CDK8_HUMAN
NC score	0.666611 (rank : 508)	θ value	1.53129e-07 (rank : 817)
Query Neighborhood Hits	2923	Target Neighborhood Hits	831	Shared Neighborhood Hits	774
SwissProt Accessions	P49336	Gene names	CDK8
Domain Architecture
Description	Cell division protein kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Protein kinase K35).

AAK1_HUMAN
NC score	0.666534 (rank : 509)	θ value	5.81887e-07 (rank : 854)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1077	Shared Neighborhood Hits	882
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

CLK4_HUMAN
NC score	0.665819 (rank : 510)	θ value	2.60593e-15 (rank : 403)
Query Neighborhood Hits	2923	Target Neighborhood Hits	759	Shared Neighborhood Hits	733
SwissProt Accessions	Q9HAZ1	Gene names	CLK4
Domain Architecture
Description	Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4).

WEE1_MOUSE
NC score	0.665697 (rank : 511)	θ value	2.61198e-07 (rank : 839)
Query Neighborhood Hits	2923	Target Neighborhood Hits	794	Shared Neighborhood Hits	739
SwissProt Accessions	P47810, Q9EPL7	Gene names	Wee1
Domain Architecture
Description	Wee1-like protein kinase (EC 2.7.10.2) (Wee1A kinase).

FGFR4_MOUSE
NC score	0.665619 (rank : 512)	θ value	1.58096e-12 (rank : 514)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1026	Shared Neighborhood Hits	965
SwissProt Accessions	Q03142, Q5J7D9, Q8C3V5, Q8CIB8	Gene names	Fgfr4, Fgfr-4, Mpk-11
Domain Architecture
Description	Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1) (FGFR-4) (Protein-tyrosine kinase receptor MPK-11) (CD334 antigen).

AAK1_MOUSE
NC score	0.665291 (rank : 513)	θ value	4.45536e-07 (rank : 847)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1051	Shared Neighborhood Hits	872
SwissProt Accessions	Q3UHJ0, Q3TY53, Q6ZPZ6, Q80XP6	Gene names	Aak1, Kiaa1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

CLK4_MOUSE
NC score	0.664668 (rank : 514)	θ value	7.58209e-15 (rank : 418)
Query Neighborhood Hits	2923	Target Neighborhood Hits	759	Shared Neighborhood Hits	734
SwissProt Accessions	O35493, O35721, Q8CEU9, Q99LU6	Gene names	Clk4
Domain Architecture
Description	Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4).

BMP2K_MOUSE
NC score	0.664119 (rank : 515)	θ value	1.87187e-05 (rank : 944)
Query Neighborhood Hits	2923	Target Neighborhood Hits	874	Shared Neighborhood Hits	761
SwissProt Accessions	Q91Z96, Q8C8L7	Gene names	Bmp2k, Bike
Domain Architecture
Description	BMP-2-inducible protein kinase (EC 2.7.11.1) (BIKe).

GAK_HUMAN
NC score	0.664050 (rank : 516)	θ value	9.92553e-07 (rank : 876)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1028	Shared Neighborhood Hits	830
SwissProt Accessions	O14976, Q9BVY6	Gene names	GAK
Domain Architecture
Description	Cyclin G-associated kinase (EC 2.7.11.1).

E2AK1_HUMAN
NC score	0.663993 (rank : 517)	θ value	1.81305 (rank : 1930)
Query Neighborhood Hits	2923	Target Neighborhood Hits	833	Shared Neighborhood Hits	777
SwissProt Accessions	Q9BQI3, Q8NBW3, Q9HC02, Q9NYE0, Q9P0V6, Q9P1J5, Q9P2H8, Q9UHG4	Gene names	EIF2AK1, HRI, KIAA1369
Domain Architecture
Description	Eukaryotic translation initiation factor 2-alpha kinase 1 (EC 2.7.11.1) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Heme-controlled repressor) (HCR) (Hemin-sensitive initiation factor 2-alpha kinase).

TAOK1_MOUSE
NC score	0.663560 (rank : 518)	θ value	4.59992e-12 (rank : 546)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1720	Shared Neighborhood Hits	1145
SwissProt Accessions	Q5F2E8, Q69ZL2, Q8JZX2, Q91VG7	Gene names	Taok1, Kiaa1361
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1).

TAOK1_HUMAN
NC score	0.663289 (rank : 519)	θ value	6.00763e-12 (rank : 556)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1734	Shared Neighborhood Hits	1154
SwissProt Accessions	Q7L7X3, Q96L75, Q9H2K7, Q9H7S5, Q9P2I6	Gene names	TAOK1, KIAA1361, MAP3K16
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1) (STE20-like kinase PSK2) (Kinase from chicken homolog B) (hKFC-B).

BMP2K_HUMAN
NC score	0.663035 (rank : 520)	θ value	9.29e-05 (rank : 994)
Query Neighborhood Hits	2923	Target Neighborhood Hits	867	Shared Neighborhood Hits	772
SwissProt Accessions	Q9NSY1, O94791, Q8IYF2, Q8N2G7, Q8NHG9, Q9NTG8	Gene names	BMP2K, BIKE
Domain Architecture
Description	BMP-2-inducible protein kinase (EC 2.7.11.1) (BIKe).

WNK3_HUMAN
NC score	0.662935 (rank : 521)	θ value	8.11959e-09 (rank : 739)
Query Neighborhood Hits	2923	Target Neighborhood Hits	948	Shared Neighborhood Hits	785
SwissProt Accessions	Q9BYP7, Q9HCK6	Gene names	WNK3, KIAA1566, PRKWNK3
Domain Architecture
Description	Serine/threonine-protein kinase WNK3 (EC 2.7.11.1) (Protein kinase with no lysine 3) (Protein kinase, lysine-deficient 3).

GAK_MOUSE
NC score	0.661503 (rank : 522)	θ value	7.59969e-07 (rank : 866)
Query Neighborhood Hits	2923	Target Neighborhood Hits	964	Shared Neighborhood Hits	802
SwissProt Accessions	Q99KY4, Q6P1I8, Q6P9S5, Q8BM74, Q8K0Q4	Gene names	Gak
Domain Architecture	No domain graphic available
Description	Cyclin G-associated kinase (EC 2.7.11.1).

CLK2_HUMAN
NC score	0.661283 (rank : 523)	θ value	1.2105e-12 (rank : 506)
Query Neighborhood Hits	2923	Target Neighborhood Hits	752	Shared Neighborhood Hits	734
SwissProt Accessions	P49760, Q96CQ0	Gene names	CLK2
Domain Architecture
Description	Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2).

M3K12_HUMAN
NC score	0.660953 (rank : 524)	θ value	2.61198e-07 (rank : 833)
Query Neighborhood Hits	2923	Target Neighborhood Hits	940	Shared Neighborhood Hits	820
SwissProt Accessions	Q12852, Q86VQ5, Q8WY25	Gene names	MAP3K12, ZPK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

M3K12_MOUSE
NC score	0.660675 (rank : 525)	θ value	2.61198e-07 (rank : 834)
Query Neighborhood Hits	2923	Target Neighborhood Hits	957	Shared Neighborhood Hits	820
SwissProt Accessions	Q60700, P70286, Q3TLL7, Q8C4N7, Q8CBX3, Q8CDL6	Gene names	Map3k12, Zpk
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

WNK1_HUMAN
NC score	0.660280 (rank : 526)	θ value	1.25267e-09 (rank : 675)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1158	Shared Neighborhood Hits	880
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

WNK4_MOUSE
NC score	0.659767 (rank : 527)	θ value	1.25267e-09 (rank : 676)
Query Neighborhood Hits	2923	Target Neighborhood Hits	961	Shared Neighborhood Hits	799
SwissProt Accessions	Q80UE6, Q4VAC1, Q80XB5, Q80XN2, Q8R0N0, Q8R340	Gene names	Wnk4, Prkwnk4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

RIPK5_HUMAN
NC score	0.658961 (rank : 528)	θ value	0.000158464 (rank : 1019)
Query Neighborhood Hits	2923	Target Neighborhood Hits	864	Shared Neighborhood Hits	792
SwissProt Accessions	Q6XUX3, O75060, Q5RKT0, Q6IN87, Q6P997, Q86Y03, Q9P1S5	Gene names	RIPK5, KIAA0472, RIP5
Domain Architecture	No domain graphic available
Description	Receptor-interacting serine/threonine-protein kinase 5 (EC 2.7.11.1) (Dusty protein kinase) (Dusty PK) (RIP-homologous kinase).

WNK1_MOUSE
NC score	0.658753 (rank : 529)	θ value	9.59137e-10 (rank : 668)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1179	Shared Neighborhood Hits	866
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

RIPK5_MOUSE
NC score	0.658517 (rank : 530)	θ value	0.000158464 (rank : 1020)
Query Neighborhood Hits	2923	Target Neighborhood Hits	874	Shared Neighborhood Hits	794
SwissProt Accessions	Q6XUX1, Q3ULK4, Q5EBN5, Q8C7D4, Q8C923, Q9CTP7	Gene names	Ripk5
Domain Architecture	No domain graphic available
Description	Receptor-interacting serine/threonine-protein kinase 5 (EC 2.7.11.1) (Dusty protein kinase) (Dusty PK).

NTRK2_MOUSE
NC score	0.658135 (rank : 531)	θ value	1.63604e-09 (rank : 683)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1088	Shared Neighborhood Hits	942
SwissProt Accessions	P15209, Q3TUF9, Q80WU0, Q91XJ9	Gene names	Ntrk2, Trkb
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B).

NTRK2_HUMAN
NC score	0.657981 (rank : 532)	θ value	1.25267e-09 (rank : 671)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1081	Shared Neighborhood Hits	942
SwissProt Accessions	Q16620, Q16675, Q8WXJ6	Gene names	NTRK2, TRKB
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB) (Trk-B).

TYRO3_HUMAN
NC score	0.656745 (rank : 533)	θ value	7.84624e-12 (rank : 562)
Query Neighborhood Hits	2923	Target Neighborhood Hits	995	Shared Neighborhood Hits	935
SwissProt Accessions	Q06418, O14953, Q86VR3	Gene names	TYRO3, BYK, DTK, RSE, SKY
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine- protein kinase DTK) (Protein-tyrosine kinase byk).

WNK2_HUMAN
NC score	0.656492 (rank : 534)	θ value	6.88961 (rank : 2710)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1407	Shared Neighborhood Hits	955
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

WEE1_HUMAN
NC score	0.655538 (rank : 535)	θ value	5.81887e-07 (rank : 863)
Query Neighborhood Hits	2923	Target Neighborhood Hits	777	Shared Neighborhood Hits	725
SwissProt Accessions	P30291	Gene names	WEE1
Domain Architecture
Description	Wee1-like protein kinase (EC 2.7.10.2) (Wee1A kinase) (WEE1hu).

TESK1_MOUSE
NC score	0.654549 (rank : 536)	θ value	6.43352e-06 (rank : 922)
Query Neighborhood Hits	2923	Target Neighborhood Hits	862	Shared Neighborhood Hits	780
SwissProt Accessions	O70146, O70147	Gene names	Tesk1
Domain Architecture
Description	Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein kinase 1).

TYRO3_MOUSE
NC score	0.654376 (rank : 537)	θ value	8.67504e-11 (rank : 619)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1007	Shared Neighborhood Hits	943
SwissProt Accessions	P55144, O09070, O09080, P70285, Q60752, Q62482, Q62483, Q62484, Q78E85, Q78E87	Gene names	Tyro3, Dtk, Rse
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase DTK) (TK19-2) (Etk2/tyro3).

M3K7_MOUSE
NC score	0.654259 (rank : 538)	θ value	2.44474e-05 (rank : 955)
Query Neighborhood Hits	2923	Target Neighborhood Hits	892	Shared Neighborhood Hits	799
SwissProt Accessions	Q62073	Gene names	Map3k7, Tak1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta- activated kinase 1).

M3K7_HUMAN
NC score	0.654099 (rank : 539)	θ value	2.44474e-05 (rank : 954)
Query Neighborhood Hits	2923	Target Neighborhood Hits	892	Shared Neighborhood Hits	798
SwissProt Accessions	O43318, O43317, O43319, Q5TDN2, Q5TDN3	Gene names	MAP3K7, TAK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta- activated kinase 1).

TESK2_HUMAN
NC score	0.653949 (rank : 540)	θ value	3.19293e-05 (rank : 970)
Query Neighborhood Hits	2923	Target Neighborhood Hits	851	Shared Neighborhood Hits	771
SwissProt Accessions	Q96S53, Q8N520, Q9Y3Q6	Gene names	TESK2
Domain Architecture
Description	Dual specificity testis-specific protein kinase 2 (EC 2.7.12.1) (Testicular protein kinase 2).

WNK4_HUMAN
NC score	0.653744 (rank : 541)	θ value	θ > 10 (rank : 3129)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1043	Shared Neighborhood Hits	839
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

TESK2_MOUSE
NC score	0.653542 (rank : 542)	θ value	0.000158464 (rank : 1023)
Query Neighborhood Hits	2923	Target Neighborhood Hits	833	Shared Neighborhood Hits	766
SwissProt Accessions	Q8VCT9	Gene names	Tesk2
Domain Architecture
Description	Dual specificity testis-specific protein kinase 2 (EC 2.7.12.1) (Testicular protein kinase 2).

TESK1_HUMAN
NC score	0.653121 (rank : 543)	θ value	6.43352e-06 (rank : 921)
Query Neighborhood Hits	2923	Target Neighborhood Hits	864	Shared Neighborhood Hits	775
SwissProt Accessions	Q15569	Gene names	TESK1
Domain Architecture
Description	Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein kinase 1).

E2AK4_HUMAN
NC score	0.652742 (rank : 544)	θ value	0.279714 (rank : 1493)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1012	Shared Neighborhood Hits	866
SwissProt Accessions	Q9P2K8, Q69YL7, Q6DC97, Q96GN6, Q9H5K1, Q9NSQ3, Q9NSZ5, Q9UJ56	Gene names	EIF2AK4, GCN2, KIAA1338
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 2-alpha kinase 4 (EC 2.7.11.1) (GCN2-like protein).

VGFR3_MOUSE
NC score	0.651977 (rank : 545)	θ value	9.90251e-15 (rank : 425)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1056	Shared Neighborhood Hits	990
SwissProt Accessions	P35917	Gene names	Flt4, Flt-4
Domain Architecture
Description	Vascular endothelial growth factor receptor 3 precursor (EC 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4).

CLK2_MOUSE
NC score	0.651912 (rank : 546)	θ value	2.0648e-12 (rank : 523)
Query Neighborhood Hits	2923	Target Neighborhood Hits	743	Shared Neighborhood Hits	728
SwissProt Accessions	O35491	Gene names	Clk2
Domain Architecture
Description	Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2).

ROCK2_HUMAN
NC score	0.651278 (rank : 547)	θ value	1.24977e-17 (rank : 341)
Query Neighborhood Hits	2923	Target Neighborhood Hits	2073	Shared Neighborhood Hits	1187
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

TRIB1_HUMAN
NC score	0.650459 (rank : 548)	θ value	4.30538e-10 (rank : 653)
Query Neighborhood Hits	2923	Target Neighborhood Hits	598	Shared Neighborhood Hits	581
SwissProt Accessions	Q96RU8, O15180, Q9H2Y8	Gene names	TRIB1, C8FW, GIG2, TRB1
Domain Architecture	No domain graphic available
Description	Tribbles homolog 1 (TRB-1) (SKIP1) (G-protein-coupled receptor-induced protein 2) (GIG-2).

TRIB1_MOUSE
NC score	0.648864 (rank : 549)	θ value	1.25267e-09 (rank : 674)
Query Neighborhood Hits	2923	Target Neighborhood Hits	593	Shared Neighborhood Hits	579
SwissProt Accessions	Q8K4K4, Q8BFS7, Q8BJR9, Q8BZX3, Q91W04	Gene names	Trib1, Trb1
Domain Architecture	No domain graphic available
Description	Tribbles homolog 1 (TRB-1).

CTRO_HUMAN
NC score	0.648527 (rank : 550)	θ value	4.29542e-18 (rank : 322)
Query Neighborhood Hits	2923	Target Neighborhood Hits	2092	Shared Neighborhood Hits	1195
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

VGFR3_HUMAN
NC score	0.648322 (rank : 551)	θ value	6.85773e-16 (rank : 387)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1037	Shared Neighborhood Hits	968
SwissProt Accessions	P35916	Gene names	FLT4
Domain Architecture
Description	Vascular endothelial growth factor receptor 3 precursor (EC 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4).

MRCKA_HUMAN
NC score	0.648233 (rank : 552)	θ value	2.88119e-14 (rank : 440)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1999	Shared Neighborhood Hits	1174
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

IRAK4_MOUSE
NC score	0.648210 (rank : 553)	θ value	1.29631e-06 (rank : 886)
Query Neighborhood Hits	2923	Target Neighborhood Hits	820	Shared Neighborhood Hits	757
SwissProt Accessions	Q8R4K2, Q80WW1	Gene names	Irak4
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1) (IRAK-4).

ROCK1_HUMAN
NC score	0.648162 (rank : 554)	θ value	5.60996e-18 (rank : 329)
Query Neighborhood Hits	2923	Target Neighborhood Hits	2000	Shared Neighborhood Hits	1175
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

E2AK4_MOUSE
NC score	0.647605 (rank : 555)	θ value	θ > 10 (rank : 2990)
Query Neighborhood Hits	2923	Target Neighborhood Hits	984	Shared Neighborhood Hits	844
SwissProt Accessions	Q9QZ05, Q6GQT4, Q6ZPT5, Q8C5S0, Q8CIF5, Q9CT30, Q9CUV9, Q9ESB6, Q9ESB7, Q9ESB8	Gene names	Eif2ak4, Gcn2, Kiaa1338
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 2-alpha kinase 4 (EC 2.7.11.1) (GCN2-like protein) (mGCN2).

M3K11_HUMAN
NC score	0.646568 (rank : 556)	θ value	2.61198e-07 (rank : 832)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1136	Shared Neighborhood Hits	877
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

RAF1_MOUSE
NC score	0.646460 (rank : 557)	θ value	1.47974e-10 (rank : 629)
Query Neighborhood Hits	2923	Target Neighborhood Hits	886	Shared Neighborhood Hits	790
SwissProt Accessions	Q99N57, Q91WH1	Gene names	Raf1, Craf
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

M3K9_HUMAN
NC score	0.645886 (rank : 558)	θ value	3.41135e-07 (rank : 843)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1123	Shared Neighborhood Hits	867
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

ROCK2_MOUSE
NC score	0.645785 (rank : 559)	θ value	1.058e-16 (rank : 359)
Query Neighborhood Hits	2923	Target Neighborhood Hits	2072	Shared Neighborhood Hits	1200
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

RIPK1_HUMAN
NC score	0.645740 (rank : 560)	θ value	0.0252991 (rank : 1257)
Query Neighborhood Hits	2923	Target Neighborhood Hits	891	Shared Neighborhood Hits	798
SwissProt Accessions	Q13546, Q13180	Gene names	RIPK1, RIP
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

RAF1_HUMAN
NC score	0.645618 (rank : 561)	θ value	1.133e-10 (rank : 625)
Query Neighborhood Hits	2923	Target Neighborhood Hits	886	Shared Neighborhood Hits	787
SwissProt Accessions	P04049	Gene names	RAF1, RAF
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

M3K10_HUMAN
NC score	0.644406 (rank : 562)	θ value	5.81887e-07 (rank : 860)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1071	Shared Neighborhood Hits	851
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

IRAK4_HUMAN
NC score	0.643727 (rank : 563)	θ value	2.61198e-07 (rank : 830)
Query Neighborhood Hits	2923	Target Neighborhood Hits	816	Shared Neighborhood Hits	759
SwissProt Accessions	Q9NWZ3, Q8TDF7, Q9Y589	Gene names	IRAK4
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1) (IRAK-4) (NY- REN-64 antigen).

BRAF1_HUMAN
NC score	0.643374 (rank : 564)	θ value	2.13673e-09 (rank : 691)
Query Neighborhood Hits	2923	Target Neighborhood Hits	883	Shared Neighborhood Hits	781
SwissProt Accessions	P15056, Q13878, Q9Y6T3	Gene names	BRAF, BRAF1, RAFB1
Domain Architecture
Description	B-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1).

CLK3_HUMAN
NC score	0.642971 (rank : 565)	θ value	2.69671e-12 (rank : 531)
Query Neighborhood Hits	2923	Target Neighborhood Hits	748	Shared Neighborhood Hits	725
SwissProt Accessions	P49761, Q9BRS3, Q9BUJ7	Gene names	CLK3
Domain Architecture
Description	Dual specificity protein kinase CLK3 (EC 2.7.12.1) (CDC-like kinase 3).

CLK3_MOUSE
NC score	0.642456 (rank : 566)	θ value	2.69671e-12 (rank : 532)
Query Neighborhood Hits	2923	Target Neighborhood Hits	761	Shared Neighborhood Hits	728
SwissProt Accessions	O35492	Gene names	Clk3
Domain Architecture
Description	Dual specificity protein kinase CLK3 (EC 2.7.12.1) (CDC-like kinase 3).

MLTK_MOUSE
NC score	0.641175 (rank : 567)	θ value	2.98157e-11 (rank : 585)
Query Neighborhood Hits	2923	Target Neighborhood Hits	874	Shared Neighborhood Hits	779
SwissProt Accessions	Q9ESL4, Q3V1X8, Q8BR73, Q9ESL3	Gene names	Mltk
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif kinase ZAK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK).

MLTK_HUMAN
NC score	0.640781 (rank : 568)	θ value	5.08577e-11 (rank : 598)
Query Neighborhood Hits	2923	Target Neighborhood Hits	911	Shared Neighborhood Hits	791
SwissProt Accessions	Q9NYL2, Q53SX1, Q580W8, Q59GY5, Q86YW8, Q9HCC4, Q9HCC5, Q9HDD2, Q9NYE9	Gene names	MLTK, ZAK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Cervical cancer suppressor gene 4 protein).

ARAF_HUMAN
NC score	0.640431 (rank : 569)	θ value	8.97725e-08 (rank : 789)
Query Neighborhood Hits	2923	Target Neighborhood Hits	924	Shared Neighborhood Hits	794
SwissProt Accessions	P10398, P07557, Q5H9B3	Gene names	ARAF, ARAF1, PKS, PKS2
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (A- raf-1) (Proto-oncogene Pks).

ARAF_MOUSE
NC score	0.640425 (rank : 570)	θ value	8.97725e-08 (rank : 790)
Query Neighborhood Hits	2923	Target Neighborhood Hits	874	Shared Neighborhood Hits	781
SwissProt Accessions	P04627, Q99J44, Q9CTT5, Q9D6R6, Q9DBU7	Gene names	Araf, A-raf, Araf1
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1).

MRCKB_MOUSE
NC score	0.640020 (rank : 571)	θ value	3.40345e-15 (rank : 408)
Query Neighborhood Hits	2923	Target Neighborhood Hits	2180	Shared Neighborhood Hits	1229
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

ROR1_MOUSE
NC score	0.639787 (rank : 572)	θ value	3.29651e-10 (rank : 646)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1025	Shared Neighborhood Hits	937
SwissProt Accessions	Q9Z139	Gene names	Ror1, Ntrkr1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1) (mROR1).

M3KL4_HUMAN
NC score	0.638942 (rank : 573)	θ value	1.80886e-08 (rank : 757)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1087	Shared Neighborhood Hits	862
SwissProt Accessions	Q5TCX8, Q5TCX7, Q5TCX9, Q8WWN1, Q8WWN2, Q96JM1	Gene names	MLK4, KIAA1804
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase 4).

RIPK1_MOUSE
NC score	0.638780 (rank : 574)	θ value	0.00509761 (rank : 1159)
Query Neighborhood Hits	2923	Target Neighborhood Hits	874	Shared Neighborhood Hits	787
SwissProt Accessions	Q60855, Q3U0J3, Q8CD90	Gene names	Ripk1, Rinp, Rip
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

ROR1_HUMAN
NC score	0.638624 (rank : 575)	θ value	8.11959e-09 (rank : 738)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1018	Shared Neighborhood Hits	929
SwissProt Accessions	Q01973, Q92776	Gene names	ROR1, NTRKR1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1).

WEE1B_MOUSE
NC score	0.638523 (rank : 576)	θ value	1.43324e-05 (rank : 943)
Query Neighborhood Hits	2923	Target Neighborhood Hits	765	Shared Neighborhood Hits	715
SwissProt Accessions	Q66JT0, Q4U4S4, Q7TPV9	Gene names	Wee1b, Wee2
Domain Architecture	No domain graphic available
Description	Wee1-like protein kinase 1B (EC 2.7.10.2) (Wee1B kinase) (mWee1B).

ROCK1_MOUSE
NC score	0.637679 (rank : 577)	θ value	5.60996e-18 (rank : 330)
Query Neighborhood Hits	2923	Target Neighborhood Hits	2126	Shared Neighborhood Hits	1209
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

WEE1B_HUMAN
NC score	0.637401 (rank : 578)	θ value	2.44474e-05 (rank : 963)
Query Neighborhood Hits	2923	Target Neighborhood Hits	836	Shared Neighborhood Hits	746
SwissProt Accessions	P0C1S8	Gene names	WEE1B, WEE2
Domain Architecture	No domain graphic available
Description	Wee1-like protein kinase 1B (EC 2.7.10.2) (Wee1B kinase).

MOS_HUMAN
NC score	0.636724 (rank : 579)	θ value	0.000121331 (rank : 1014)
Query Neighborhood Hits	2923	Target Neighborhood Hits	829	Shared Neighborhood Hits	773
SwissProt Accessions	P00540	Gene names	MOS
Domain Architecture
Description	Proto-oncogene serine/threonine-protein kinase mos (EC 2.7.11.1) (c- mos) (Oocyte maturation factor mos).

TRIB3_MOUSE
NC score	0.636330 (rank : 580)	θ value	9.92553e-07 (rank : 880)
Query Neighborhood Hits	2923	Target Neighborhood Hits	578	Shared Neighborhood Hits	566
SwissProt Accessions	Q8K4K2, Q3UMQ0, Q921E7	Gene names	Trib3, Nipk, Trb3
Domain Architecture
Description	Tribbles homolog 3 (TRB-3) (Neuronal cell death-inducible putative kinase).

MRCKB_HUMAN
NC score	0.634691 (rank : 581)	θ value	1.99529e-15 (rank : 399)
Query Neighborhood Hits	2923	Target Neighborhood Hits	2239	Shared Neighborhood Hits	1228
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

CTRO_MOUSE
NC score	0.634245 (rank : 582)	θ value	3.28887e-18 (rank : 318)
Query Neighborhood Hits	2923	Target Neighborhood Hits	2344	Shared Neighborhood Hits	1261
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

NTRK3_HUMAN
NC score	0.633348 (rank : 583)	θ value	5.62301e-10 (rank : 656)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1115	Shared Neighborhood Hits	930
SwissProt Accessions	Q16288, Q12827, Q16289	Gene names	NTRK3, TRKC
Domain Architecture
Description	NT-3 growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C).

ROR2_HUMAN
NC score	0.633213 (rank : 584)	θ value	5.62301e-10 (rank : 657)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1014	Shared Neighborhood Hits	924
SwissProt Accessions	Q01974, Q59GF5, Q5SPI5, Q9HAY7, Q9HB61	Gene names	ROR2, NTRKR2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2).

MOS_MOUSE
NC score	0.632442 (rank : 585)	θ value	7.1131e-05 (rank : 990)
Query Neighborhood Hits	2923	Target Neighborhood Hits	833	Shared Neighborhood Hits	773
SwissProt Accessions	P00536	Gene names	Mos
Domain Architecture	No domain graphic available
Description	Proto-oncogene serine/threonine-protein kinase mos (EC 2.7.11.1) (c- mos) (Oocyte maturation factor mos).

LIMK2_HUMAN
NC score	0.629596 (rank : 586)	θ value	0.00298849 (rank : 1128)
Query Neighborhood Hits	2923	Target Neighborhood Hits	986	Shared Neighborhood Hits	778
SwissProt Accessions	P53671, Q7KZ80, Q96E10, Q99464	Gene names	LIMK2
Domain Architecture
Description	LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2).

LIMK1_HUMAN
NC score	0.627971 (rank : 587)	θ value	2.21117e-06 (rank : 894)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1005	Shared Neighborhood Hits	791
SwissProt Accessions	P53667, O15283, Q15820, Q15821, Q75MU3, Q9Y5Q1	Gene names	LIMK1, LIMK
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1).

LIMK1_MOUSE
NC score	0.627685 (rank : 588)	θ value	3.77169e-06 (rank : 907)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1008	Shared Neighborhood Hits	789
SwissProt Accessions	P53668	Gene names	Limk1, Limk
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (KIZ-1).

LIMK2_MOUSE
NC score	0.627234 (rank : 589)	θ value	0.00228821 (rank : 1120)
Query Neighborhood Hits	2923	Target Neighborhood Hits	998	Shared Neighborhood Hits	781
SwissProt Accessions	O54785, O54776, O55238, Q9QUL4	Gene names	Limk2
Domain Architecture
Description	LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2).

JAK3_MOUSE
NC score	0.625994 (rank : 590)	θ value	8.11959e-09 (rank : 735)
Query Neighborhood Hits	2923	Target Neighborhood Hits	821	Shared Neighborhood Hits	762
SwissProt Accessions	Q62137, Q61746, Q61747	Gene names	Jak3
Domain Architecture
Description	Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3).

TIE2_HUMAN
NC score	0.624978 (rank : 591)	θ value	4.76016e-09 (rank : 725)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1192	Shared Neighborhood Hits	907
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

TIE2_MOUSE
NC score	0.624526 (rank : 592)	θ value	4.45536e-07 (rank : 853)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1204	Shared Neighborhood Hits	905
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

JAK2_HUMAN
NC score	0.624339 (rank : 593)	θ value	3.64472e-09 (rank : 714)
Query Neighborhood Hits	2923	Target Neighborhood Hits	847	Shared Neighborhood Hits	781
SwissProt Accessions	O60674, O14636, O75297	Gene names	JAK2
Domain Architecture
Description	Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2).

KSR2_HUMAN
NC score	0.623773 (rank : 594)	θ value	8.40245e-06 (rank : 925)
Query Neighborhood Hits	2923	Target Neighborhood Hits	920	Shared Neighborhood Hits	804
SwissProt Accessions	Q6VAB6, Q8N775	Gene names	KSR2
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-2 (hKSR2).

MYO3A_MOUSE
NC score	0.623732 (rank : 595)	θ value	5.08577e-11 (rank : 599)
Query Neighborhood Hits	2923	Target Neighborhood Hits	902	Shared Neighborhood Hits	819
SwissProt Accessions	Q8K3H5	Gene names	Myo3a
Domain Architecture
Description	Myosin IIIA (EC 2.7.11.1).

JAK2_MOUSE
NC score	0.623204 (rank : 596)	θ value	2.79066e-09 (rank : 701)
Query Neighborhood Hits	2923	Target Neighborhood Hits	839	Shared Neighborhood Hits	778
SwissProt Accessions	Q62120, Q62124	Gene names	Jak2
Domain Architecture
Description	Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2).

TIE1_MOUSE
NC score	0.621926 (rank : 597)	θ value	1.38499e-08 (rank : 752)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1266	Shared Neighborhood Hits	948
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TRIB3_HUMAN
NC score	0.620650 (rank : 598)	θ value	1.17247e-07 (rank : 812)
Query Neighborhood Hits	2923	Target Neighborhood Hits	519	Shared Neighborhood Hits	509
SwissProt Accessions	Q96RU7, Q53GU4, Q53ZW7, Q6I9Y9, Q8TAI6, Q9H5M8, Q9NUD2	Gene names	TRIB3, C20orf97, NIPK, SKIP3, TRB3
Domain Architecture
Description	Tribbles homolog 3 (TRB-3) (Neuronal cell death-inducible putative kinase) (p65-interacting inhibitor of NF-kappaB) (SINK).

RIPK3_HUMAN
NC score	0.620156 (rank : 599)	θ value	0.47712 (rank : 1628)
Query Neighborhood Hits	2923	Target Neighborhood Hits	828	Shared Neighborhood Hits	764
SwissProt Accessions	Q9Y572	Gene names	RIPK3, RIP3
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3).

JAK3_HUMAN
NC score	0.619701 (rank : 600)	θ value	2.79066e-09 (rank : 702)
Query Neighborhood Hits	2923	Target Neighborhood Hits	827	Shared Neighborhood Hits	767
SwissProt Accessions	P52333, Q13259, Q13260, Q13611, Q9Y6S2	Gene names	JAK3
Domain Architecture
Description	Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK).

MYO3A_HUMAN
NC score	0.619606 (rank : 601)	θ value	3.89403e-11 (rank : 591)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1033	Shared Neighborhood Hits	883
SwissProt Accessions	Q8NEV4, Q8WX17, Q9NYS8	Gene names	MYO3A
Domain Architecture
Description	Myosin IIIA (EC 2.7.11.1).

RIPK3_MOUSE
NC score	0.619378 (rank : 602)	θ value	0.0148317 (rank : 1224)
Query Neighborhood Hits	2923	Target Neighborhood Hits	867	Shared Neighborhood Hits	770
SwissProt Accessions	Q9QZL0	Gene names	Ripk3, Rip3
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (mRIP3).

ROR2_MOUSE
NC score	0.618283 (rank : 603)	θ value	4.76016e-09 (rank : 724)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1000	Shared Neighborhood Hits	907
SwissProt Accessions	Q9Z138	Gene names	Ror2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2) (mROR2).

TYK2_HUMAN
NC score	0.617601 (rank : 604)	θ value	6.21693e-09 (rank : 734)
Query Neighborhood Hits	2923	Target Neighborhood Hits	841	Shared Neighborhood Hits	778
SwissProt Accessions	P29597, Q6QB10, Q96CH0	Gene names	TYK2
Domain Architecture
Description	Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2).

UFO_MOUSE
NC score	0.617305 (rank : 605)	θ value	8.40245e-06 (rank : 929)
Query Neighborhood Hits	2923	Target Neighborhood Hits	988	Shared Neighborhood Hits	899
SwissProt Accessions	Q00993	Gene names	Axl, Ark, Ufo
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (Adhesion-related kinase).

MERTK_MOUSE
NC score	0.616444 (rank : 606)	θ value	1.06045e-08 (rank : 742)
Query Neighborhood Hits	2923	Target Neighborhood Hits	974	Shared Neighborhood Hits	903
SwissProt Accessions	Q60805, Q62194	Gene names	Mertk, Mer
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

TYK2_MOUSE
NC score	0.614866 (rank : 607)	θ value	1.17247e-07 (rank : 813)
Query Neighborhood Hits	2923	Target Neighborhood Hits	850	Shared Neighborhood Hits	783
SwissProt Accessions	Q9R117, O88431, Q8VE41	Gene names	Tyk2
Domain Architecture
Description	Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2).

TIE1_HUMAN
NC score	0.614546 (rank : 608)	θ value	2.61198e-07 (rank : 838)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1241	Shared Neighborhood Hits	930
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

MYO3B_HUMAN
NC score	0.614127 (rank : 609)	θ value	6.21693e-09 (rank : 730)
Query Neighborhood Hits	2923	Target Neighborhood Hits	923	Shared Neighborhood Hits	818
SwissProt Accessions	Q8WXR4, Q8IX64, Q8IX65, Q8IX66, Q8IX67, Q8IX68	Gene names	MYO3B
Domain Architecture
Description	Myosin IIIB (EC 2.7.11.1).

MERTK_HUMAN
NC score	0.613277 (rank : 610)	θ value	3.29651e-10 (rank : 643)
Query Neighborhood Hits	2923	Target Neighborhood Hits	988	Shared Neighborhood Hits	923
SwissProt Accessions	Q12866, Q9HBB4	Gene names	MERTK, MER
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

FES_MOUSE
NC score	0.612898 (rank : 611)	θ value	4.76016e-09 (rank : 719)
Query Neighborhood Hits	2923	Target Neighborhood Hits	980	Shared Neighborhood Hits	823
SwissProt Accessions	P16879, Q62122	Gene names	Fes, Fps
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

PINK1_MOUSE
NC score	0.611666 (rank : 612)	θ value	4.03905 (rank : 2332)
Query Neighborhood Hits	2923	Target Neighborhood Hits	726	Shared Neighborhood Hits	685
SwissProt Accessions	Q99MQ3, Q7TMZ3, Q811I8, Q91XU5	Gene names	Pink1
Domain Architecture
Description	Serine/threonine-protein kinase PINK1, mitochondrial precursor (EC 2.7.11.1) (PTEN-induced putative kinase protein 1) (BRPK).

FES_HUMAN
NC score	0.611492 (rank : 613)	θ value	1.63604e-09 (rank : 679)
Query Neighborhood Hits	2923	Target Neighborhood Hits	978	Shared Neighborhood Hits	805
SwissProt Accessions	P07332	Gene names	FES, FPS
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

JAK1_HUMAN
NC score	0.611232 (rank : 614)	θ value	1.02475e-11 (rank : 565)
Query Neighborhood Hits	2923	Target Neighborhood Hits	858	Shared Neighborhood Hits	783
SwissProt Accessions	P23458	Gene names	JAK1, JAK1A
Domain Architecture
Description	Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1).

LRRK1_HUMAN
NC score	0.610963 (rank : 615)	θ value	1.29631e-06 (rank : 887)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1237	Shared Neighborhood Hits	819
SwissProt Accessions	Q38SD2, Q6NVH5, Q6NYC0, Q6ZNL9, Q6ZNM9, Q96JN5, Q9H5S3	Gene names	LRRK1, KIAA1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

PGFRA_HUMAN
NC score	0.610137 (rank : 616)	θ value	8.67504e-11 (rank : 617)
Query Neighborhood Hits	2923	Target Neighborhood Hits	980	Shared Neighborhood Hits	904
SwissProt Accessions	P16234, Q96KZ7	Gene names	PDGFRA
Domain Architecture
Description	Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen).

UFO_HUMAN
NC score	0.608960 (rank : 617)	θ value	1.09739e-05 (rank : 938)
Query Neighborhood Hits	2923	Target Neighborhood Hits	981	Shared Neighborhood Hits	896
SwissProt Accessions	P30530	Gene names	AXL, UFO
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (AXL oncogene).

LRRK1_MOUSE
NC score	0.608595 (rank : 618)	θ value	4.45536e-07 (rank : 850)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1267	Shared Neighborhood Hits	824
SwissProt Accessions	Q3UHC2, Q3U476, Q66JQ4, Q6GQR9, Q6NZF5, Q6ZPI4, Q8BKP3, Q8BU93, Q8BUY0, Q8BVV2, Q8R085	Gene names	Lrrk1, Kiaa1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

PINK1_HUMAN
NC score	0.608318 (rank : 619)	θ value	θ > 10 (rank : 3065)
Query Neighborhood Hits	2923	Target Neighborhood Hits	741	Shared Neighborhood Hits	691
SwissProt Accessions	Q9BXM7, Q8N6T9, Q8NBU3, Q96DE4	Gene names	PINK1
Domain Architecture
Description	Serine/threonine-protein kinase PINK1, mitochondrial precursor (EC 2.7.11.1) (PTEN-induced putative kinase protein 1) (BRPK).

EPHA7_HUMAN
NC score	0.608211 (rank : 620)	θ value	1.133e-10 (rank : 620)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1053	Shared Neighborhood Hits	890
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

EPHA7_MOUSE
NC score	0.607997 (rank : 621)	θ value	4.30538e-10 (rank : 649)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1025	Shared Neighborhood Hits	885
SwissProt Accessions	Q61772, Q61505, Q61773, Q61774	Gene names	Epha7, Ebk, Ehk3, Mdk1
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1).

PGFRA_MOUSE
NC score	0.607034 (rank : 622)	θ value	2.79066e-09 (rank : 705)
Query Neighborhood Hits	2923	Target Neighborhood Hits	975	Shared Neighborhood Hits	905
SwissProt Accessions	P26618, Q62046	Gene names	Pdgfra
Domain Architecture
Description	Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen).

KSR1_MOUSE
NC score	0.606130 (rank : 623)	θ value	1.17247e-07 (rank : 807)
Query Neighborhood Hits	2923	Target Neighborhood Hits	870	Shared Neighborhood Hits	769
SwissProt Accessions	Q61097, Q61648, Q78DX8	Gene names	Ksr1, Ksr
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras) (mKSR1) (Hb protein).

PTK6_HUMAN
NC score	0.606009 (rank : 624)	θ value	2.79066e-09 (rank : 707)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1020	Shared Neighborhood Hits	788
SwissProt Accessions	Q13882	Gene names	PTK6, BRK
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK).

JAK1_MOUSE
NC score	0.605056 (rank : 625)	θ value	1.9326e-10 (rank : 634)
Query Neighborhood Hits	2923	Target Neighborhood Hits	854	Shared Neighborhood Hits	780
SwissProt Accessions	P52332, Q62126	Gene names	Jak1
Domain Architecture
Description	Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1).

PTK6_MOUSE
NC score	0.604913 (rank : 626)	θ value	2.79066e-09 (rank : 708)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1026	Shared Neighborhood Hits	791
SwissProt Accessions	Q64434	Gene names	Ptk6, Sik
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related intestinal kinase).

AL2S2_HUMAN
NC score	0.604258 (rank : 627)	θ value	θ > 10 (rank : 2934)
Query Neighborhood Hits	2923	Target Neighborhood Hits	727	Shared Neighborhood Hits	686
SwissProt Accessions	Q9C0K7, Q5BKY7, Q9P1L0	Gene names	ALS2CR2, ILPIP
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ALS2CR2 (EC 2.7.11.1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein) (ILP- interacting protein) (CALS-21).

EPHA3_HUMAN
NC score	0.604148 (rank : 628)	θ value	1.47974e-10 (rank : 627)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1005	Shared Neighborhood Hits	887
SwissProt Accessions	P29320, Q9H2V3, Q9H2V4	Gene names	EPHA3, ETK, ETK1, HEK
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4).

FER_HUMAN
NC score	0.602957 (rank : 629)	θ value	9.26847e-13 (rank : 504)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1278	Shared Neighborhood Hits	963
SwissProt Accessions	P16591	Gene names	FER, TYK3
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2) (p94-FER) (c- FER).

KSYK_HUMAN
NC score	0.601998 (rank : 630)	θ value	3.29651e-10 (rank : 642)
Query Neighborhood Hits	2923	Target Neighborhood Hits	901	Shared Neighborhood Hits	763
SwissProt Accessions	P43405	Gene names	SYK
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

KSYK_MOUSE
NC score	0.601838 (rank : 631)	θ value	1.63604e-09 (rank : 681)
Query Neighborhood Hits	2923	Target Neighborhood Hits	944	Shared Neighborhood Hits	779
SwissProt Accessions	P48025	Gene names	Syk
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

EPHB1_HUMAN
NC score	0.600810 (rank : 632)	θ value	2.28291e-11 (rank : 577)
Query Neighborhood Hits	2923	Target Neighborhood Hits	988	Shared Neighborhood Hits	862
SwissProt Accessions	P54762, O43569, O95142, O95143	Gene names	EPHB1, EPHT2, NET
Domain Architecture
Description	Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK).

EPHA5_MOUSE
NC score	0.600809 (rank : 633)	θ value	1.06045e-08 (rank : 740)
Query Neighborhood Hits	2923	Target Neighborhood Hits	950	Shared Neighborhood Hits	863
SwissProt Accessions	Q60629	Gene names	Epha5, Bsk, Cek7, Ehk1
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7).

EPHA3_MOUSE
NC score	0.600191 (rank : 634)	θ value	7.84624e-12 (rank : 558)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1009	Shared Neighborhood Hits	889
SwissProt Accessions	P29319	Gene names	Epha3, Etk1, Mek4, Tyro4
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (MEK4).

EPHB4_MOUSE
NC score	0.600117 (rank : 635)	θ value	4.76016e-09 (rank : 718)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1013	Shared Neighborhood Hits	871
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

ZAP70_HUMAN
NC score	0.599778 (rank : 636)	θ value	4.30538e-10 (rank : 654)
Query Neighborhood Hits	2923	Target Neighborhood Hits	893	Shared Neighborhood Hits	765
SwissProt Accessions	P43403	Gene names	ZAP70, SRK
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

PGFRB_MOUSE
NC score	0.599387 (rank : 637)	θ value	3.29651e-10 (rank : 645)
Query Neighborhood Hits	2923	Target Neighborhood Hits	960	Shared Neighborhood Hits	897
SwissProt Accessions	P05622	Gene names	Pdgfrb, Pdgfr
Domain Architecture
Description	Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen).

EPHA5_HUMAN
NC score	0.599370 (rank : 638)	θ value	8.67504e-11 (rank : 612)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1009	Shared Neighborhood Hits	883
SwissProt Accessions	P54756	Gene names	EPHA5, EHK1, HEK7
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein- tyrosine kinase HEK7).

FAK1_HUMAN
NC score	0.599158 (rank : 639)	θ value	7.34386e-10 (rank : 659)
Query Neighborhood Hits	2923	Target Neighborhood Hits	850	Shared Neighborhood Hits	775
SwissProt Accessions	Q05397, Q14291, Q9UD85	Gene names	PTK2, FAK, FAK1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK) (Protein- tyrosine kinase 2).

ZAP70_MOUSE
NC score	0.598602 (rank : 640)	θ value	1.63604e-09 (rank : 690)
Query Neighborhood Hits	2923	Target Neighborhood Hits	905	Shared Neighborhood Hits	773
SwissProt Accessions	P43404	Gene names	Zap70, Srk, Zap-70
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

FAK1_MOUSE
NC score	0.598555 (rank : 641)	θ value	2.79066e-09 (rank : 700)
Query Neighborhood Hits	2923	Target Neighborhood Hits	850	Shared Neighborhood Hits	770
SwissProt Accessions	P34152, O08578	Gene names	Ptk2, Fadk, Fak, Fak1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK).

ROS_HUMAN
NC score	0.598182 (rank : 642)	θ value	1.63604e-09 (rank : 686)
Query Neighborhood Hits	2923	Target Neighborhood Hits	907	Shared Neighborhood Hits	831
SwissProt Accessions	P08922, Q15368	Gene names	ROS1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ROS precursor (EC 2.7.10.1) (c- ros-1).

RPKL1_MOUSE
NC score	0.597629 (rank : 643)	θ value	8.40245e-06 (rank : 928)
Query Neighborhood Hits	2923	Target Neighborhood Hits	704	Shared Neighborhood Hits	658
SwissProt Accessions	Q8R2S1, Q8R1D4	Gene names	Rps6kl1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase-like 1 (EC 2.7.11.1).

KSR1_HUMAN
NC score	0.597551 (rank : 644)	θ value	7.59969e-07 (rank : 868)
Query Neighborhood Hits	2923	Target Neighborhood Hits	867	Shared Neighborhood Hits	755
SwissProt Accessions	Q8IVT5, Q13476	Gene names	KSR1, KSR
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras).

EPHB4_HUMAN
NC score	0.596688 (rank : 645)	θ value	2.13673e-09 (rank : 693)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1056	Shared Neighborhood Hits	878
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

EPHA4_MOUSE
NC score	0.596460 (rank : 646)	θ value	1.02475e-11 (rank : 563)
Query Neighborhood Hits	2923	Target Neighborhood Hits	982	Shared Neighborhood Hits	868
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

TEC_MOUSE
NC score	0.595828 (rank : 647)	θ value	1.99992e-07 (rank : 826)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1006	Shared Neighborhood Hits	787
SwissProt Accessions	P24604, Q9R1M9, Q9WVN0, Q9WVN1, Q9WVN2, Q9WVN3	Gene names	Tec
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

AL2S2_MOUSE
NC score	0.595625 (rank : 648)	θ value	θ > 10 (rank : 2935)
Query Neighborhood Hits	2923	Target Neighborhood Hits	709	Shared Neighborhood Hits	677
SwissProt Accessions	Q8K4T3, Q6P922, Q8BU86, Q8BXK0, Q8K4T2	Gene names	Als2cr2, Papk
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ALS2CR2 (EC 2.7.11.1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein homolog) (ILP-interacting protein homolog) (Polyploidy-associated protein kinase).

PGFRB_HUMAN
NC score	0.595048 (rank : 649)	θ value	2.79066e-09 (rank : 706)
Query Neighborhood Hits	2923	Target Neighborhood Hits	962	Shared Neighborhood Hits	898
SwissProt Accessions	P09619, Q8N5L4	Gene names	PDGFRB
Domain Architecture
Description	Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen).

EPHA4_HUMAN
NC score	0.594954 (rank : 650)	θ value	2.28291e-11 (rank : 576)
Query Neighborhood Hits	2923	Target Neighborhood Hits	975	Shared Neighborhood Hits	865
SwissProt Accessions	P54764	Gene names	EPHA4, HEK8, SEK
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8).

EPHA8_HUMAN
NC score	0.594390 (rank : 651)	θ value	1.25267e-09 (rank : 669)
Query Neighborhood Hits	2923	Target Neighborhood Hits	956	Shared Neighborhood Hits	871
SwissProt Accessions	P29322, Q9NUA9, Q9P269	Gene names	EPHA8, EEK, KIAA1459
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3).

RPKL1_HUMAN
NC score	0.594344 (rank : 652)	θ value	7.1131e-05 (rank : 992)
Query Neighborhood Hits	2923	Target Neighborhood Hits	708	Shared Neighborhood Hits	649
SwissProt Accessions	Q9Y6S9, Q69YT9, Q6ZMQ6, Q96NR9, Q9BSU9	Gene names	RPS6KL1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase-like 1 (EC 2.7.11.1).

CDC7_HUMAN
NC score	0.593273 (rank : 653)	θ value	9.29e-05 (rank : 996)
Query Neighborhood Hits	2923	Target Neighborhood Hits	652	Shared Neighborhood Hits	625
SwissProt Accessions	O00311, O00558	Gene names	CDC7, CDC7L1
Domain Architecture
Description	Cell division cycle 7-related protein kinase (EC 2.7.11.1) (CDC7- related kinase) (HsCdc7) (huCdc7).

LRRK2_HUMAN
NC score	0.591903 (rank : 654)	θ value	9.29e-05 (rank : 1002)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1382	Shared Neighborhood Hits	835
SwissProt Accessions	Q5S007, Q6ZS50, Q8NCX9	Gene names	LRRK2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin).

EPHA8_MOUSE
NC score	0.591888 (rank : 655)	θ value	1.63604e-09 (rank : 678)
Query Neighborhood Hits	2923	Target Neighborhood Hits	969	Shared Neighborhood Hits	869
SwissProt Accessions	O09127	Gene names	Epha8, Eek
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase).

CSK_MOUSE
NC score	0.591399 (rank : 656)	θ value	4.92598e-06 (rank : 911)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1009	Shared Neighborhood Hits	788
SwissProt Accessions	P41241, Q03143	Gene names	Csk
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase MPK-2) (p50CSK).

TEC_HUMAN
NC score	0.591282 (rank : 657)	θ value	1.53129e-07 (rank : 823)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1006	Shared Neighborhood Hits	784
SwissProt Accessions	P42680	Gene names	TEC, PSCTK4
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

EPHB2_MOUSE
NC score	0.591192 (rank : 658)	θ value	2.13673e-09 (rank : 692)
Query Neighborhood Hits	2923	Target Neighborhood Hits	982	Shared Neighborhood Hits	858
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

EPHB2_HUMAN
NC score	0.591006 (rank : 659)	θ value	3.64472e-09 (rank : 712)
Query Neighborhood Hits	2923	Target Neighborhood Hits	983	Shared Neighborhood Hits	858
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

TXK_HUMAN
NC score	0.590836 (rank : 660)	θ value	1.47974e-10 (rank : 633)
Query Neighborhood Hits	2923	Target Neighborhood Hits	971	Shared Neighborhood Hits	775
SwissProt Accessions	P42681, Q14220	Gene names	TXK
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2).

EPHA2_HUMAN
NC score	0.590631 (rank : 661)	θ value	3.08544e-08 (rank : 763)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1021	Shared Neighborhood Hits	866
SwissProt Accessions	P29317	Gene names	EPHA2, ECK
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase).

ABL1_MOUSE
NC score	0.590323 (rank : 662)	θ value	2.61198e-07 (rank : 828)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1178	Shared Neighborhood Hits	869
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

KIT_MOUSE
NC score	0.589756 (rank : 663)	θ value	4.76016e-09 (rank : 720)
Query Neighborhood Hits	2923	Target Neighborhood Hits	949	Shared Neighborhood Hits	888
SwissProt Accessions	P05532, Q61415, Q61416, Q61417, Q6LEE9	Gene names	Kit, Sl
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

FAK2_MOUSE
NC score	0.589210 (rank : 664)	θ value	1.06045e-08 (rank : 741)
Query Neighborhood Hits	2923	Target Neighborhood Hits	851	Shared Neighborhood Hits	765
SwissProt Accessions	Q9QVP9	Gene names	Ptk2b, Fak2, Pyk2, Raftk
Domain Architecture	No domain graphic available
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

EPHB3_HUMAN
NC score	0.589061 (rank : 665)	θ value	3.64472e-09 (rank : 713)
Query Neighborhood Hits	2923	Target Neighborhood Hits	996	Shared Neighborhood Hits	873
SwissProt Accessions	P54753, Q7Z740	Gene names	EPHB3, ETK2, HEK2
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2).

CDC7_MOUSE
NC score	0.588976 (rank : 666)	θ value	0.00020696 (rank : 1028)
Query Neighborhood Hits	2923	Target Neighborhood Hits	641	Shared Neighborhood Hits	621
SwissProt Accessions	Q9Z0H0, Q9Z2Y7	Gene names	Cdc7, Cdc7l1
Domain Architecture
Description	Cell division cycle 7-related protein kinase (EC 2.7.11.1) (CDC7- related kinase) (muCdc7).

EPHB3_MOUSE
NC score	0.588665 (rank : 667)	θ value	1.38499e-08 (rank : 745)
Query Neighborhood Hits	2923	Target Neighborhood Hits	996	Shared Neighborhood Hits	874
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

CSF1R_MOUSE
NC score	0.588653 (rank : 668)	θ value	2.69671e-12 (rank : 533)
Query Neighborhood Hits	2923	Target Neighborhood Hits	983	Shared Neighborhood Hits	916
SwissProt Accessions	P09581, Q3U3P1, Q9DBH9	Gene names	Csf1r, Csfmr, Fms
Domain Architecture
Description	Macrophage colony-stimulating factor 1 receptor precursor (EC 2.7.10.1) (CSF-1-R) (Fms proto-oncogene) (c-fms) (CD115 antigen).

ABL1_HUMAN
NC score	0.588375 (rank : 669)	θ value	1.99992e-07 (rank : 824)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1220	Shared Neighborhood Hits	860
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

SRMS_MOUSE
NC score	0.587422 (rank : 670)	θ value	3.29651e-10 (rank : 647)
Query Neighborhood Hits	2923	Target Neighborhood Hits	964	Shared Neighborhood Hits	782
SwissProt Accessions	Q62270, Q62360, Q923M5	Gene names	Srms, Srm
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70).

BMX_HUMAN
NC score	0.587417 (rank : 671)	θ value	9.59137e-10 (rank : 663)
Query Neighborhood Hits	2923	Target Neighborhood Hits	942	Shared Neighborhood Hits	773
SwissProt Accessions	P51813, O60564, Q12871	Gene names	BMX
Domain Architecture
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38).

EPHA2_MOUSE
NC score	0.587269 (rank : 672)	θ value	5.26297e-08 (rank : 773)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1020	Shared Neighborhood Hits	857
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

BMX_MOUSE
NC score	0.587028 (rank : 673)	θ value	2.79066e-09 (rank : 698)
Query Neighborhood Hits	2923	Target Neighborhood Hits	912	Shared Neighborhood Hits	764
SwissProt Accessions	P97504	Gene names	Bmx
Domain Architecture	No domain graphic available
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein homolog).

KIT_HUMAN
NC score	0.586199 (rank : 674)	θ value	2.79066e-09 (rank : 703)
Query Neighborhood Hits	2923	Target Neighborhood Hits	953	Shared Neighborhood Hits	886
SwissProt Accessions	P10721, Q9UM99	Gene names	KIT
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

ITK_MOUSE
NC score	0.585958 (rank : 675)	θ value	1.17247e-07 (rank : 806)
Query Neighborhood Hits	2923	Target Neighborhood Hits	985	Shared Neighborhood Hits	782
SwissProt Accessions	Q03526	Gene names	Itk, Emt, Tlk, Tsk
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK).

ITK_HUMAN
NC score	0.585958 (rank : 676)	θ value	4.0297e-08 (rank : 771)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1016	Shared Neighborhood Hits	791
SwissProt Accessions	Q08881	Gene names	ITK, EMT, LYK
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT).

CSK_HUMAN
NC score	0.585543 (rank : 677)	θ value	3.41135e-07 (rank : 841)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1009	Shared Neighborhood Hits	787
SwissProt Accessions	P41240, Q6FGZ6	Gene names	CSK
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase CYL).

BTK_HUMAN
NC score	0.585125 (rank : 678)	θ value	3.08544e-08 (rank : 762)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1026	Shared Neighborhood Hits	785
SwissProt Accessions	Q06187	Gene names	BTK, AGMX1, ATK, BPK
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK).

MATK_MOUSE
NC score	0.585105 (rank : 679)	θ value	4.45536e-07 (rank : 851)
Query Neighborhood Hits	2923	Target Neighborhood Hits	952	Shared Neighborhood Hits	780
SwissProt Accessions	P41242, Q6LE90	Gene names	Matk, Ctk, Ntk
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK).

FAK2_HUMAN
NC score	0.584927 (rank : 680)	θ value	1.38499e-08 (rank : 746)
Query Neighborhood Hits	2923	Target Neighborhood Hits	847	Shared Neighborhood Hits	761
SwissProt Accessions	Q14289, Q13475, Q14290, Q16709	Gene names	PTK2B, FAK2, PYK2, RAFTK
Domain Architecture
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

BTK_MOUSE
NC score	0.584460 (rank : 681)	θ value	6.87365e-08 (rank : 782)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1017	Shared Neighborhood Hits	785
SwissProt Accessions	P35991, Q61365	Gene names	Btk, Bpk
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB).

ABL2_HUMAN
NC score	0.584133 (rank : 682)	θ value	2.88788e-06 (rank : 897)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1045	Shared Neighborhood Hits	797
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

LYN_MOUSE
NC score	0.583788 (rank : 683)	θ value	3.08544e-08 (rank : 765)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1023	Shared Neighborhood Hits	799
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

FRK_HUMAN
NC score	0.583428 (rank : 684)	θ value	1.53129e-07 (rank : 818)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1058	Shared Neighborhood Hits	796
SwissProt Accessions	P42685, Q13128	Gene names	FRK
Domain Architecture
Description	Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear tyrosine protein kinase RAK).

SRMS_HUMAN
NC score	0.583027 (rank : 685)	θ value	4.30538e-10 (rank : 652)
Query Neighborhood Hits	2923	Target Neighborhood Hits	946	Shared Neighborhood Hits	781
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).

LYN_HUMAN
NC score	0.582622 (rank : 686)	θ value	1.17247e-07 (rank : 808)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1022	Shared Neighborhood Hits	797
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

TNK1_MOUSE
NC score	0.582604 (rank : 687)	θ value	5.81887e-07 (rank : 862)
Query Neighborhood Hits	2923	Target Neighborhood Hits	806	Shared Neighborhood Hits	737
SwissProt Accessions	Q99ML2, Q8CCC4, Q8K0X9, Q91V11	Gene names	Tnk1, Kos1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (Kinase of embryonic stem cells).

MATK_HUMAN
NC score	0.582091 (rank : 688)	θ value	1.17247e-07 (rank : 810)
Query Neighborhood Hits	2923	Target Neighborhood Hits	954	Shared Neighborhood Hits	777
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

TXK_MOUSE
NC score	0.579694 (rank : 689)	θ value	1.63604e-09 (rank : 689)
Query Neighborhood Hits	2923	Target Neighborhood Hits	980	Shared Neighborhood Hits	767
SwissProt Accessions	P42682	Gene names	Txk, Rlk
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18) (Resting lymphocyte kinase).

NTRK1_HUMAN
NC score	0.577809 (rank : 690)	θ value	1.09739e-05 (rank : 937)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1023	Shared Neighborhood Hits	857
SwissProt Accessions	P04629, P08119, Q15655, Q15656, Q5D056, Q5VZS2, Q9UIU7	Gene names	NTRK1, TRK
Domain Architecture
Description	High affinity nerve growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1 transforming tyrosine kinase protein) (p140-TrkA) (Trk-A).

LRRK2_MOUSE
NC score	0.576806 (rank : 691)	θ value	0.000786445 (rank : 1076)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1359	Shared Neighborhood Hits	826
SwissProt Accessions	Q5S006, Q8BWG7, Q8BZJ6, Q8CI84, Q8K062	Gene names	Lrrk2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1).

LCK_MOUSE
NC score	0.576666 (rank : 692)	θ value	1.47974e-10 (rank : 628)
Query Neighborhood Hits	2923	Target Neighborhood Hits	981	Shared Neighborhood Hits	778
SwissProt Accessions	P06240, Q61794, Q61795, Q62320, Q91X65	Gene names	Lck, Lsk-t
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK).

KS6C1_MOUSE
NC score	0.576650 (rank : 693)	θ value	0.00390308 (rank : 1139)
Query Neighborhood Hits	2923	Target Neighborhood Hits	700	Shared Neighborhood Hits	636
SwissProt Accessions	Q8BLK9, Q3UDY3, Q6PDY4, Q8BMQ5, Q8BX49	Gene names	Rps6kc1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase delta-1 (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase).

TNK1_HUMAN
NC score	0.575751 (rank : 694)	θ value	6.21693e-09 (rank : 733)
Query Neighborhood Hits	2923	Target Neighborhood Hits	815	Shared Neighborhood Hits	739
SwissProt Accessions	Q13470, O95364, Q8IYI4	Gene names	TNK1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1).

TTBK1_HUMAN
NC score	0.575563 (rank : 695)	θ value	0.00390308 (rank : 1144)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1058	Shared Neighborhood Hits	822
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

DSCL1_HUMAN
NC score	0.575410 (rank : 696)	θ value	1.96772e-63 (rank : 18)
Query Neighborhood Hits	2923	Target Neighborhood Hits	589	Shared Neighborhood Hits	502
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

RET_HUMAN
NC score	0.575084 (rank : 697)	θ value	2.44474e-05 (rank : 958)
Query Neighborhood Hits	2923	Target Neighborhood Hits	873	Shared Neighborhood Hits	774
SwissProt Accessions	P07949, Q15250	Gene names	RET
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

RET_MOUSE
NC score	0.573834 (rank : 698)	θ value	9.29e-05 (rank : 1005)
Query Neighborhood Hits	2923	Target Neighborhood Hits	884	Shared Neighborhood Hits	778
SwissProt Accessions	P35546, Q8BQ34, Q9QXH9	Gene names	Ret
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

RIPK2_MOUSE
NC score	0.573219 (rank : 699)	θ value	2.36792 (rank : 2097)
Query Neighborhood Hits	2923	Target Neighborhood Hits	776	Shared Neighborhood Hits	707
SwissProt Accessions	P58801	Gene names	Ripk2
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1).

RIPK2_HUMAN
NC score	0.573143 (rank : 700)	θ value	θ > 10 (rank : 3085)
Query Neighborhood Hits	2923	Target Neighborhood Hits	774	Shared Neighborhood Hits	708
SwissProt Accessions	O43353, Q6UWF0	Gene names	RIPK2, CARDIAK, RICK, RIP2
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (CARD-containing interleukin-1 beta-converting enzyme- associated kinase) (CARD-containing IL-1 beta ICE-kinase).

ACK1_HUMAN
NC score	0.573137 (rank : 701)	θ value	9.92553e-07 (rank : 873)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1140	Shared Neighborhood Hits	896
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

DSCAM_HUMAN
NC score	0.573024 (rank : 702)	θ value	1.11475e-66 (rank : 17)
Query Neighborhood Hits	2923	Target Neighborhood Hits	524	Shared Neighborhood Hits	473
SwissProt Accessions	O60469, O60468	Gene names	DSCAM
Domain Architecture
Description	Down syndrome cell adhesion molecule precursor (CHD2).

KS6C1_HUMAN
NC score	0.572920 (rank : 703)	θ value	0.00228821 (rank : 1118)
Query Neighborhood Hits	2923	Target Neighborhood Hits	682	Shared Neighborhood Hits	633
SwissProt Accessions	Q96S38, Q8TDD3, Q9NSF4, Q9UL66	Gene names	RPS6KC1, RPK118
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase delta-1 (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase) (Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein) (SPHK1-binding protein).

LCK_HUMAN
NC score	0.572544 (rank : 704)	θ value	4.30538e-10 (rank : 650)
Query Neighborhood Hits	2923	Target Neighborhood Hits	987	Shared Neighborhood Hits	782
SwissProt Accessions	P06239, P07100, Q12850, Q13152, Q5TDH8, Q5TDH9, Q96DW4, Q9NYT8	Gene names	LCK
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell- specific protein-tyrosine kinase).

HCK_HUMAN
NC score	0.571807 (rank : 705)	θ value	5.26297e-08 (rank : 774)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1035	Shared Neighborhood Hits	796
SwissProt Accessions	P08631, Q5T7K1, Q5T7K2, Q96CC0, Q9H5Y5, Q9NUA4, Q9UMJ5	Gene names	HCK
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p59-HCK/p60-HCK) (Hemopoietic cell kinase).

BLK_HUMAN
NC score	0.571574 (rank : 706)	θ value	3.77169e-06 (rank : 905)
Query Neighborhood Hits	2923	Target Neighborhood Hits	994	Shared Neighborhood Hits	783
SwissProt Accessions	P51451, Q16291	Gene names	BLK
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

BLK_MOUSE
NC score	0.571426 (rank : 707)	θ value	1.29631e-06 (rank : 882)
Query Neighborhood Hits	2923	Target Neighborhood Hits	992	Shared Neighborhood Hits	780
SwissProt Accessions	P16277	Gene names	Blk
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

ACK1_MOUSE
NC score	0.571035 (rank : 708)	θ value	4.45536e-07 (rank : 848)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1080	Shared Neighborhood Hits	868
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

STYK1_HUMAN
NC score	0.570727 (rank : 709)	θ value	0.00020696 (rank : 1035)
Query Neighborhood Hits	2923	Target Neighborhood Hits	786	Shared Neighborhood Hits	735
SwissProt Accessions	Q6J9G0, Q9BXY2, Q9NSH1	Gene names	STYK1, NOK
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (Protein PK-unique).

EPHA1_HUMAN
NC score	0.569889 (rank : 710)	θ value	9.26847e-13 (rank : 503)
Query Neighborhood Hits	2923	Target Neighborhood Hits	997	Shared Neighborhood Hits	828
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

FYN_HUMAN
NC score	0.568559 (rank : 711)	θ value	1.87187e-05 (rank : 945)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1078	Shared Neighborhood Hits	794
SwissProt Accessions	P06241	Gene names	FYN
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK).

HCK_MOUSE
NC score	0.567577 (rank : 712)	θ value	6.87365e-08 (rank : 784)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1029	Shared Neighborhood Hits	795
SwissProt Accessions	P08103	Gene names	Hck
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK).

INSR_MOUSE
NC score	0.566400 (rank : 713)	θ value	5.81887e-07 (rank : 857)
Query Neighborhood Hits	2923	Target Neighborhood Hits	968	Shared Neighborhood Hits	817
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

INSR_HUMAN
NC score	0.566132 (rank : 714)	θ value	1.17247e-07 (rank : 805)
Query Neighborhood Hits	2923	Target Neighborhood Hits	963	Shared Neighborhood Hits	816
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

TTBK2_HUMAN
NC score	0.565721 (rank : 715)	θ value	0.0252991 (rank : 1259)
Query Neighborhood Hits	2923	Target Neighborhood Hits	822	Shared Neighborhood Hits	740
SwissProt Accessions	Q6IQ55, O94932, Q6ZN52, Q8IVV1	Gene names	TTBK2, KIAA0847
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 2 (EC 2.7.11.1).

SRC_MOUSE
NC score	0.564438 (rank : 716)	θ value	0.00035302 (rank : 1049)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1033	Shared Neighborhood Hits	785
SwissProt Accessions	P05480	Gene names	Src
Domain Architecture
Description	Neuronal proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c-Src) (pp60c-src).

CSF1R_HUMAN
NC score	0.564431 (rank : 717)	θ value	1.17247e-07 (rank : 803)
Query Neighborhood Hits	2923	Target Neighborhood Hits	943	Shared Neighborhood Hits	878
SwissProt Accessions	P07333, Q6LDW5, Q6LDY4	Gene names	CSF1R, FMS
Domain Architecture
Description	Macrophage colony-stimulating factor 1 receptor precursor (EC 2.7.10.1) (CSF-1-R) (Fms proto-oncogene) (c-fms) (CD115 antigen).

FYN_MOUSE
NC score	0.563894 (rank : 718)	θ value	0.000270298 (rank : 1038)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1073	Shared Neighborhood Hits	795
SwissProt Accessions	P39688	Gene names	Fyn
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn).

SRC_HUMAN
NC score	0.563103 (rank : 719)	θ value	9.29e-05 (rank : 1007)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1058	Shared Neighborhood Hits	791
SwissProt Accessions	P12931, Q86VB9, Q9H5A8	Gene names	SRC, SRC1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c- Src) (pp60c-src).

EPHA1_MOUSE
NC score	0.561666 (rank : 720)	θ value	6.64225e-11 (rank : 602)
Query Neighborhood Hits	2923	Target Neighborhood Hits	958	Shared Neighborhood Hits	815
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

TTBK2_MOUSE
NC score	0.561646 (rank : 721)	θ value	0.0330416 (rank : 1277)
Query Neighborhood Hits	2923	Target Neighborhood Hits	811	Shared Neighborhood Hits	728
SwissProt Accessions	Q3UVR3, Q3TSR6, Q3UFW0, Q571D1, Q8BKA4, Q924U8	Gene names	Ttbk2, Kiaa0847, Ttbk1
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 2.

YES_HUMAN
NC score	0.560776 (rank : 722)	θ value	3.19293e-05 (rank : 971)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1059	Shared Neighborhood Hits	793
SwissProt Accessions	P07947	Gene names	YES1, YES
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

ROBO3_HUMAN
NC score	0.560646 (rank : 723)	θ value	2.95404e-43 (rank : 40)
Query Neighborhood Hits	2923	Target Neighborhood Hits	570	Shared Neighborhood Hits	479
SwissProt Accessions	Q96MS0	Gene names	ROBO3
Domain Architecture
Description	Roundabout homolog 3 precursor (Roundabout-like protein 3).

NCAM2_MOUSE
NC score	0.560598 (rank : 724)	θ value	4.2656e-42 (rank : 47)
Query Neighborhood Hits	2923	Target Neighborhood Hits	472	Shared Neighborhood Hits	446
SwissProt Accessions	O35136, O35962	Gene names	Ncam2, Ocam, Rncam
Domain Architecture
Description	Neural cell adhesion molecule 2 precursor (N-CAM 2) (RB-8 neural cell adhesion molecule) (R4B12).

YES_MOUSE
NC score	0.560165 (rank : 725)	θ value	4.1701e-05 (rank : 979)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1052	Shared Neighborhood Hits	786
SwissProt Accessions	Q04736	Gene names	Yes1, Yes
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

IRAK1_HUMAN
NC score	0.559047 (rank : 726)	θ value	θ > 10 (rank : 3028)
Query Neighborhood Hits	2923	Target Neighborhood Hits	820	Shared Neighborhood Hits	728
SwissProt Accessions	P51617, Q7Z5V4, Q96RL2	Gene names	IRAK1, IRAK
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1).

FGR_HUMAN
NC score	0.558094 (rank : 727)	θ value	1.17247e-07 (rank : 804)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1067	Shared Neighborhood Hits	801
SwissProt Accessions	P09769, Q9UIQ3	Gene names	FGR, SRC2
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

ERBB4_HUMAN
NC score	0.557226 (rank : 728)	θ value	0.0736092 (rank : 1331)
Query Neighborhood Hits	2923	Target Neighborhood Hits	910	Shared Neighborhood Hits	768
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

SDK2_HUMAN
NC score	0.557133 (rank : 729)	θ value	6.77864e-56 (rank : 24)
Query Neighborhood Hits	2923	Target Neighborhood Hits	495	Shared Neighborhood Hits	456
SwissProt Accessions	Q58EX2, Q86VY3, Q9NTD2, Q9NVB3, Q9P214	Gene names	SDK2, KIAA1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

STYK1_MOUSE
NC score	0.557057 (rank : 730)	θ value	0.00228821 (rank : 1123)
Query Neighborhood Hits	2923	Target Neighborhood Hits	779	Shared Neighborhood Hits	727
SwissProt Accessions	Q6J9G1, Q8BZH6, Q8BZT1	Gene names	Styk1, Nok
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (mNOK).

ROBO2_MOUSE
NC score	0.556889 (rank : 731)	θ value	4.2656e-42 (rank : 48)
Query Neighborhood Hits	2923	Target Neighborhood Hits	504	Shared Neighborhood Hits	461
SwissProt Accessions	Q7TPD3, Q8BJ59	Gene names	Robo2, Kiaa1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

ROBO2_HUMAN
NC score	0.556466 (rank : 732)	θ value	7.27602e-42 (rank : 51)
Query Neighborhood Hits	2923	Target Neighborhood Hits	479	Shared Neighborhood Hits	446
SwissProt Accessions	Q9HCK4, O43608	Gene names	ROBO2, KIAA1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

KC1A_HUMAN
NC score	0.556442 (rank : 733)	θ value	0.00035302 (rank : 1045)
Query Neighborhood Hits	2923	Target Neighborhood Hits	728	Shared Neighborhood Hits	712
SwissProt Accessions	P48729, Q96HD2	Gene names	CSNK1A1
Domain Architecture
Description	Casein kinase I isoform alpha (EC 2.7.11.1) (CKI-alpha) (CK1).

KC1A_MOUSE
NC score	0.556442 (rank : 734)	θ value	0.00035302 (rank : 1046)
Query Neighborhood Hits	2923	Target Neighborhood Hits	728	Shared Neighborhood Hits	712
SwissProt Accessions	Q8BK63, Q3UIL0, Q64506, Q80XI2, Q99LY3	Gene names	Csnk1a1
Domain Architecture
Description	Casein kinase I isoform alpha (EC 2.7.11.1) (CKI-alpha) (CK1).

SDK1_HUMAN
NC score	0.556173 (rank : 735)	θ value	8.28633e-54 (rank : 32)
Query Neighborhood Hits	2923	Target Neighborhood Hits	511	Shared Neighborhood Hits	449
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

EGFR_MOUSE
NC score	0.556075 (rank : 736)	θ value	0.163984 (rank : 1416)
Query Neighborhood Hits	2923	Target Neighborhood Hits	927	Shared Neighborhood Hits	776
SwissProt Accessions	Q01279	Gene names	Egfr
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1).

SDK2_MOUSE
NC score	0.556003 (rank : 737)	θ value	1.55911e-60 (rank : 19)
Query Neighborhood Hits	2923	Target Neighborhood Hits	480	Shared Neighborhood Hits	443
SwissProt Accessions	Q6V4S5, Q3TTK1, Q5U5W7, Q6ZPP2	Gene names	Sdk2, Kiaa1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

KC1AL_HUMAN
NC score	0.555873 (rank : 738)	θ value	4.92598e-06 (rank : 912)
Query Neighborhood Hits	2923	Target Neighborhood Hits	734	Shared Neighborhood Hits	709
SwissProt Accessions	Q8N752	Gene names	CSNK1A1L
Domain Architecture
Description	Casein kinase I isoform alpha-like (EC 2.7.11.1) (CKI-alpha-like) (CK1).

EGFR_HUMAN
NC score	0.555458 (rank : 739)	θ value	0.163984 (rank : 1415)
Query Neighborhood Hits	2923	Target Neighborhood Hits	939	Shared Neighborhood Hits	770
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

NEO1_HUMAN
NC score	0.555356 (rank : 740)	θ value	1.20211e-36 (rank : 75)
Query Neighborhood Hits	2923	Target Neighborhood Hits	530	Shared Neighborhood Hits	460
SwissProt Accessions	Q92859, O00340	Gene names	NEO1, NGN
Domain Architecture
Description	Neogenin precursor.

IRAK1_MOUSE
NC score	0.555120 (rank : 741)	θ value	θ > 10 (rank : 3029)
Query Neighborhood Hits	2923	Target Neighborhood Hits	784	Shared Neighborhood Hits	710
SwissProt Accessions	Q62406, Q6Y3Z5, Q6Y3Z6	Gene names	Irak1, Il1rak
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK).

FGR_MOUSE
NC score	0.555100 (rank : 742)	θ value	1.43324e-05 (rank : 939)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1069	Shared Neighborhood Hits	796
SwissProt Accessions	P14234, Q61404	Gene names	Fgr
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

ROBO1_MOUSE
NC score	0.555008 (rank : 743)	θ value	7.27602e-42 (rank : 50)
Query Neighborhood Hits	2923	Target Neighborhood Hits	559	Shared Neighborhood Hits	483
SwissProt Accessions	O89026	Gene names	Robo1, Dutt1
Domain Architecture
Description	Roundabout homolog 1 precursor.

SDK1_MOUSE
NC score	0.554658 (rank : 744)	θ value	3.36421e-55 (rank : 25)
Query Neighborhood Hits	2923	Target Neighborhood Hits	495	Shared Neighborhood Hits	444
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

NCAM2_HUMAN
NC score	0.554628 (rank : 745)	θ value	1.46607e-42 (rank : 42)
Query Neighborhood Hits	2923	Target Neighborhood Hits	441	Shared Neighborhood Hits	422
SwissProt Accessions	O15394	Gene names	NCAM2, NCAM21
Domain Architecture
Description	Neural cell adhesion molecule 2 precursor (N-CAM 2).

INSRR_MOUSE
NC score	0.554380 (rank : 746)	θ value	1.99992e-07 (rank : 825)
Query Neighborhood Hits	2923	Target Neighborhood Hits	961	Shared Neighborhood Hits	801
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

DCC_HUMAN
NC score	0.553886 (rank : 747)	θ value	2.59387e-31 (rank : 121)
Query Neighborhood Hits	2923	Target Neighborhood Hits	583	Shared Neighborhood Hits	498
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

NEO1_MOUSE
NC score	0.553631 (rank : 748)	θ value	8.61488e-35 (rank : 88)
Query Neighborhood Hits	2923	Target Neighborhood Hits	523	Shared Neighborhood Hits	461
SwissProt Accessions	P97798	Gene names	Neo1, Ngn
Domain Architecture
Description	Neogenin precursor.

ROBO3_MOUSE
NC score	0.553214 (rank : 749)	θ value	5.57106e-42 (rank : 49)
Query Neighborhood Hits	2923	Target Neighborhood Hits	524	Shared Neighborhood Hits	457
SwissProt Accessions	Q9Z2I4	Gene names	Robo3, Rbig1
Domain Architecture
Description	Roundabout homolog 3 precursor (Retinoblastoma-inhibiting gene 1) (Rig-1).

DDR2_MOUSE
NC score	0.553214 (rank : 750)	θ value	3.64472e-09 (rank : 711)
Query Neighborhood Hits	2923	Target Neighborhood Hits	813	Shared Neighborhood Hits	733
SwissProt Accessions	Q62371	Gene names	Ddr2, Ntrkr3, Tkt, Tyro10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

KC1D_MOUSE
NC score	0.552674 (rank : 751)	θ value	0.00509761 (rank : 1153)
Query Neighborhood Hits	2923	Target Neighborhood Hits	737	Shared Neighborhood Hits	713
SwissProt Accessions	Q9DC28, Q3TZK2, Q99KK4	Gene names	Csnk1d
Domain Architecture
Description	Casein kinase I isoform delta (EC 2.7.11.1) (CKI-delta) (CKId).

KC1D_HUMAN
NC score	0.552657 (rank : 752)	θ value	0.00509761 (rank : 1152)
Query Neighborhood Hits	2923	Target Neighborhood Hits	737	Shared Neighborhood Hits	713
SwissProt Accessions	P48730, Q96KZ6, Q9BTN5	Gene names	CSNK1D
Domain Architecture
Description	Casein kinase I isoform delta (EC 2.7.11.1) (CKI-delta) (CKId).

ROBO1_HUMAN
NC score	0.551848 (rank : 753)	θ value	1.91475e-42 (rank : 43)
Query Neighborhood Hits	2923	Target Neighborhood Hits	529	Shared Neighborhood Hits	461
SwissProt Accessions	Q9Y6N7, Q7Z300, Q9BUS7	Gene names	ROBO1, DUTT1
Domain Architecture
Description	Roundabout homolog 1 precursor (H-Robo-1) (Deleted in U twenty twenty).

IGF1R_MOUSE
NC score	0.551284 (rank : 754)	θ value	1.29631e-06 (rank : 885)
Query Neighborhood Hits	2923	Target Neighborhood Hits	973	Shared Neighborhood Hits	810
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

INSRR_HUMAN
NC score	0.551121 (rank : 755)	θ value	8.97725e-08 (rank : 791)
Query Neighborhood Hits	2923	Target Neighborhood Hits	950	Shared Neighborhood Hits	800
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

IGF1R_HUMAN
NC score	0.550165 (rank : 756)	θ value	7.59969e-07 (rank : 867)
Query Neighborhood Hits	2923	Target Neighborhood Hits	977	Shared Neighborhood Hits	806
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

DDR2_HUMAN
NC score	0.549425 (rank : 757)	θ value	2.52405e-10 (rank : 638)
Query Neighborhood Hits	2923	Target Neighborhood Hits	818	Shared Neighborhood Hits	733
SwissProt Accessions	Q16832	Gene names	DDR2, NTRKR3, TKT, TYRO10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

KC1E_HUMAN
NC score	0.549419 (rank : 758)	θ value	0.00228821 (rank : 1116)
Query Neighborhood Hits	2923	Target Neighborhood Hits	732	Shared Neighborhood Hits	708
SwissProt Accessions	P49674	Gene names	CSNK1E
Domain Architecture
Description	Casein kinase I isoform epsilon (EC 2.7.11.1) (CKI-epsilon) (CKIe).

KC1E_MOUSE
NC score	0.549412 (rank : 759)	θ value	0.00228821 (rank : 1117)
Query Neighborhood Hits	2923	Target Neighborhood Hits	728	Shared Neighborhood Hits	708
SwissProt Accessions	Q9JMK2, Q8R389	Gene names	Csnk1e
Domain Architecture
Description	Casein kinase I isoform epsilon (EC 2.7.11.1) (CKI-epsilon) (CKIe).

RON_HUMAN
NC score	0.549383 (rank : 760)	θ value	θ > 10 (rank : 3088)
Query Neighborhood Hits	2923	Target Neighborhood Hits	842	Shared Neighborhood Hits	759
SwissProt Accessions	Q04912	Gene names	MST1R, RON
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (CDw136 antigen) [Contains: Macrophage- stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

ERBB2_MOUSE
NC score	0.548887 (rank : 761)	θ value	0.62314 (rank : 1662)
Query Neighborhood Hits	2923	Target Neighborhood Hits	918	Shared Neighborhood Hits	790
SwissProt Accessions	P70424, Q61525, Q6ZPE0	Gene names	Erbb2, Kiaa3023, Neu
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene).

OBSL1_HUMAN
NC score	0.548242 (rank : 762)	θ value	1.49966e-79 (rank : 9)
Query Neighborhood Hits	2923	Target Neighborhood Hits	354	Shared Neighborhood Hits	321
SwissProt Accessions	O75147, Q96IW3	Gene names	OBSL1, KIAA0657
Domain Architecture	No domain graphic available
Description	Obscurin-like protein 1 precursor.

DCC_MOUSE
NC score	0.548107 (rank : 763)	θ value	5.77852e-31 (rank : 126)
Query Neighborhood Hits	2923	Target Neighborhood Hits	896	Shared Neighborhood Hits	599
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

EPHA6_HUMAN
NC score	0.547325 (rank : 764)	θ value	4.76016e-09 (rank : 717)
Query Neighborhood Hits	2923	Target Neighborhood Hits	959	Shared Neighborhood Hits	838
SwissProt Accessions	Q9UF33	Gene names	EPHA6, EHK2
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

MET_MOUSE
NC score	0.546574 (rank : 765)	θ value	θ > 10 (rank : 3044)
Query Neighborhood Hits	2923	Target Neighborhood Hits	844	Shared Neighborhood Hits	755
SwissProt Accessions	P16056, Q62125	Gene names	Met
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

ERBB2_HUMAN
NC score	0.546457 (rank : 766)	θ value	0.279714 (rank : 1494)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1073	Shared Neighborhood Hits	820
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

EPHA6_MOUSE
NC score	0.545813 (rank : 767)	θ value	4.0297e-08 (rank : 770)
Query Neighborhood Hits	2923	Target Neighborhood Hits	946	Shared Neighborhood Hits	829
SwissProt Accessions	Q62413, Q8CCN2	Gene names	Epha6, Ehk-2, Ehk2
Domain Architecture
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

AATK_HUMAN
NC score	0.545024 (rank : 768)	θ value	θ > 10 (rank : 2924)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1243	Shared Neighborhood Hits	857
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

MET_HUMAN
NC score	0.544411 (rank : 769)	θ value	θ > 10 (rank : 3043)
Query Neighborhood Hits	2923	Target Neighborhood Hits	831	Shared Neighborhood Hits	750
SwissProt Accessions	P08581, O60366, Q12875, Q9UDX7, Q9UPL8	Gene names	MET
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

FLT3_MOUSE
NC score	0.543935 (rank : 770)	θ value	1.09739e-05 (rank : 933)
Query Neighborhood Hits	2923	Target Neighborhood Hits	847	Shared Neighborhood Hits	791
SwissProt Accessions	Q00342	Gene names	Flt3, Flk-2, Flt-3
Domain Architecture
Description	FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor flk-2) (Fetal liver kinase 2) (Tyrosine-protein kinase FLT3) (CD135 antigen).

RON_MOUSE
NC score	0.541793 (rank : 771)	θ value	θ > 10 (rank : 3089)
Query Neighborhood Hits	2923	Target Neighborhood Hits	836	Shared Neighborhood Hits	755
SwissProt Accessions	Q62190, Q62555	Gene names	Mst1r, Ron, Stk
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

KC1G1_MOUSE
NC score	0.541236 (rank : 772)	θ value	0.0563607 (rank : 1316)
Query Neighborhood Hits	2923	Target Neighborhood Hits	713	Shared Neighborhood Hits	694
SwissProt Accessions	Q8BTH8	Gene names	Csnk1g1
Domain Architecture
Description	Casein kinase I isoform gamma-1 (EC 2.7.11.1) (CKI-gamma 1).

TNI3K_MOUSE
NC score	0.541182 (rank : 773)	θ value	0.00869519 (rank : 1193)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1079	Shared Neighborhood Hits	765
SwissProt Accessions	Q5GIG6, Q5GIG5	Gene names	Tnni3k, Cark
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

PUNC_HUMAN
NC score	0.541104 (rank : 774)	θ value	1.24688e-25 (rank : 168)
Query Neighborhood Hits	2923	Target Neighborhood Hits	449	Shared Neighborhood Hits	393
SwissProt Accessions	Q8IVU1, O95215	Gene names	PUNC
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

NCA11_MOUSE
NC score	0.540786 (rank : 775)	θ value	3.27365e-34 (rank : 95)
Query Neighborhood Hits	2923	Target Neighborhood Hits	661	Shared Neighborhood Hits	532
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

NFASC_HUMAN
NC score	0.540589 (rank : 776)	θ value	2.12192e-33 (rank : 104)
Query Neighborhood Hits	2923	Target Neighborhood Hits	497	Shared Neighborhood Hits	449
SwissProt Accessions	O94856, Q5T2F0, Q5T2F1, Q5T2F2, Q5T2F3, Q5T2F4, Q5T2F5, Q5T2F6, Q5T2F7, Q5T2F9, Q5T2G0, Q5W9F8, Q68DH3, Q6ZQV6, Q7Z3K1, Q96HT1, Q96K50	Gene names	NFASC, KIAA0756
Domain Architecture
Description	Neurofascin precursor.

NFASC_MOUSE
NC score	0.539724 (rank : 777)	θ value	4.72714e-33 (rank : 109)
Query Neighborhood Hits	2923	Target Neighborhood Hits	475	Shared Neighborhood Hits	439
SwissProt Accessions	Q810U3	Gene names	Nfasc
Domain Architecture
Description	Neurofascin precursor.

SCYL2_HUMAN
NC score	0.539469 (rank : 778)	θ value	0.000121331 (rank : 1015)
Query Neighborhood Hits	2923	Target Neighborhood Hits	632	Shared Neighborhood Hits	575
SwissProt Accessions	Q6P3W7, Q96EF4, Q96ST4, Q9H7V5, Q9NVH3, Q9P2I7	Gene names	SCYL2, CVAK104, KIAA1360
Domain Architecture	No domain graphic available
Description	SCY1-like protein 2 (Coated vesicle-associated kinase of 104 kDa).

NRCAM_HUMAN
NC score	0.539377 (rank : 779)	θ value	1.01765e-35 (rank : 83)
Query Neighborhood Hits	2923	Target Neighborhood Hits	439	Shared Neighborhood Hits	414
SwissProt Accessions	Q92823, O15051, O15179, Q9UHI3, Q9UHI4	Gene names	NRCAM, KIAA0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (hBravo).

BOC_HUMAN
NC score	0.539298 (rank : 780)	θ value	1.33217e-27 (rank : 154)
Query Neighborhood Hits	2923	Target Neighborhood Hits	543	Shared Neighborhood Hits	418
SwissProt Accessions	Q9BWV1, Q6UXJ5, Q8N2P7, Q8NF26	Gene names	BOC
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

KC1G1_HUMAN
NC score	0.539244 (rank : 781)	θ value	0.0736092 (rank : 1343)
Query Neighborhood Hits	2923	Target Neighborhood Hits	708	Shared Neighborhood Hits	692
SwissProt Accessions	Q9HCP0, Q96AE9, Q9HCP1	Gene names	CSNK1G1
Domain Architecture
Description	Casein kinase I isoform gamma-1 (EC 2.7.11.1) (CKI-gamma 1).

CNTN2_HUMAN
NC score	0.539226 (rank : 782)	θ value	4.27553e-34 (rank : 97)
Query Neighborhood Hits	2923	Target Neighborhood Hits	440	Shared Neighborhood Hits	424
SwissProt Accessions	Q02246, P78432	Gene names	CNTN2, TAG1, TAX1
Domain Architecture
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

NCA11_HUMAN
NC score	0.539056 (rank : 783)	θ value	1.12514e-34 (rank : 91)
Query Neighborhood Hits	2923	Target Neighborhood Hits	443	Shared Neighborhood Hits	413
SwissProt Accessions	P13591, Q15829, Q16180	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 140 kDa isoform precursor (N-CAM 140) (NCAM-140) (CD56 antigen).

CNTN2_MOUSE
NC score	0.538941 (rank : 784)	θ value	1.01765e-35 (rank : 82)
Query Neighborhood Hits	2923	Target Neighborhood Hits	450	Shared Neighborhood Hits	428
SwissProt Accessions	Q61330, Q6NZJ4, Q7TSJ5	Gene names	Cntn2, Tax
Domain Architecture	No domain graphic available
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

PUNC_MOUSE
NC score	0.538915 (rank : 785)	θ value	4.73814e-25 (rank : 177)
Query Neighborhood Hits	2923	Target Neighborhood Hits	501	Shared Neighborhood Hits	403
SwissProt Accessions	Q8BQC3, O70246, Q792T2, Q9Z2S6	Gene names	Punc
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

BOC_MOUSE
NC score	0.538431 (rank : 786)	θ value	3.17079e-29 (rank : 141)
Query Neighborhood Hits	2923	Target Neighborhood Hits	433	Shared Neighborhood Hits	386
SwissProt Accessions	Q6AZB0, Q6KAM5, Q6P5H3, Q7TMJ3, Q8CE73, Q8CE91, Q8R377, Q923W7	Gene names	Boc
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

CNTN5_HUMAN
NC score	0.538283 (rank : 787)	θ value	4.41421e-39 (rank : 59)
Query Neighborhood Hits	2923	Target Neighborhood Hits	446	Shared Neighborhood Hits	433
SwissProt Accessions	O94779, O94780	Gene names	CNTN5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2) (hNB-2).

NRCAM_MOUSE
NC score	0.537469 (rank : 788)	θ value	2.12192e-33 (rank : 105)
Query Neighborhood Hits	2923	Target Neighborhood Hits	432	Shared Neighborhood Hits	399
SwissProt Accessions	Q810U4, Q80U33, Q8BLG8, Q8BX92, Q8BYJ8	Gene names	Nrcam, Kiaa0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (mBravo).

FLT3_HUMAN
NC score	0.536975 (rank : 789)	θ value	4.45536e-07 (rank : 849)
Query Neighborhood Hits	2923	Target Neighborhood Hits	843	Shared Neighborhood Hits	785
SwissProt Accessions	P36888, Q13414	Gene names	FLT3, STK1
Domain Architecture
Description	FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor FLT3) (Stem cell tyrosine kinase 1) (STK-1) (CD135 antigen).

KC1G3_HUMAN
NC score	0.536310 (rank : 790)	θ value	0.279714 (rank : 1510)
Query Neighborhood Hits	2923	Target Neighborhood Hits	711	Shared Neighborhood Hits	697
SwissProt Accessions	Q9Y6M4, Q86WZ7, Q9Y6M3	Gene names	CSNK1G3
Domain Architecture
Description	Casein kinase I isoform gamma-3 (EC 2.7.11.1) (CKI-gamma 3).

NCA12_HUMAN
NC score	0.536242 (rank : 791)	θ value	1.12514e-34 (rank : 92)
Query Neighborhood Hits	2923	Target Neighborhood Hits	437	Shared Neighborhood Hits	408
SwissProt Accessions	P13592, P13593	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120) (CD56 antigen).

L1CAM_MOUSE
NC score	0.535137 (rank : 792)	θ value	8.06329e-33 (rank : 112)
Query Neighborhood Hits	2923	Target Neighborhood Hits	457	Shared Neighborhood Hits	433
SwissProt Accessions	P11627	Gene names	L1cam, Caml1
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

AATK_MOUSE
NC score	0.534661 (rank : 793)	θ value	θ > 10 (rank : 2925)
Query Neighborhood Hits	2923	Target Neighborhood Hits	942	Shared Neighborhood Hits	777
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

CNTN3_HUMAN
NC score	0.534253 (rank : 794)	θ value	4.568e-36 (rank : 78)
Query Neighborhood Hits	2923	Target Neighborhood Hits	455	Shared Neighborhood Hits	434
SwissProt Accessions	Q9P232, Q9H039	Gene names	CNTN3, KIAA1496, PANG
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

CNTN4_MOUSE
NC score	0.534138 (rank : 795)	θ value	1.12253e-42 (rank : 41)
Query Neighborhood Hits	2923	Target Neighborhood Hits	445	Shared Neighborhood Hits	422
SwissProt Accessions	Q69Z26, Q8BRT6, Q8CBD3	Gene names	Cntn4, Kiaa3024
Domain Architecture	No domain graphic available
Description	Contactin-4 precursor (Brain-derived immunoglobulin superfamily protein 2) (BIG-2).

TNI3K_HUMAN
NC score	0.533880 (rank : 796)	θ value	θ > 10 (rank : 3117)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1084	Shared Neighborhood Hits	769
SwissProt Accessions	Q59H18, Q49AR1, Q6MZS9, Q9Y2V6	Gene names	TNNI3K, CARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

L1CAM_HUMAN
NC score	0.533828 (rank : 797)	θ value	4.568e-36 (rank : 80)
Query Neighborhood Hits	2923	Target Neighborhood Hits	457	Shared Neighborhood Hits	432
SwissProt Accessions	P32004, Q8TA87	Gene names	L1CAM, CAML1, MIC5
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

CNTN5_MOUSE
NC score	0.533634 (rank : 798)	θ value	2.86122e-38 (rank : 64)
Query Neighborhood Hits	2923	Target Neighborhood Hits	434	Shared Neighborhood Hits	418
SwissProt Accessions	P68500	Gene names	Cntn5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2).

NCA12_MOUSE
NC score	0.533550 (rank : 799)	θ value	3.27365e-34 (rank : 96)
Query Neighborhood Hits	2923	Target Neighborhood Hits	399	Shared Neighborhood Hits	387
SwissProt Accessions	P13594, Q61950	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120).

CNTN4_HUMAN
NC score	0.533376 (rank : 800)	θ value	1.62093e-41 (rank : 52)
Query Neighborhood Hits	2923	Target Neighborhood Hits	449	Shared Neighborhood Hits	425
SwissProt Accessions	Q8IWV2, Q8IX14, Q8TC35	Gene names	CNTN4
Domain Architecture	No domain graphic available
Description	Contactin-4 precursor (Brain-derived immunoglobulin superfamily protein 2) (BIG-2).

CDON_MOUSE
NC score	0.533002 (rank : 801)	θ value	1.4233e-29 (rank : 138)
Query Neighborhood Hits	2923	Target Neighborhood Hits	410	Shared Neighborhood Hits	374
SwissProt Accessions	Q32MD9, O88971	Gene names	Cdon, Cdo
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

CDON_HUMAN
NC score	0.532382 (rank : 802)	θ value	5.06226e-27 (rank : 159)
Query Neighborhood Hits	2923	Target Neighborhood Hits	412	Shared Neighborhood Hits	367
SwissProt Accessions	Q4KMG0, O14631	Gene names	CDON, CDO
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

DDR1_MOUSE
NC score	0.529623 (rank : 803)	θ value	2.36244e-08 (rank : 759)
Query Neighborhood Hits	2923	Target Neighborhood Hits	818	Shared Neighborhood Hits	731
SwissProt Accessions	Q03146	Gene names	Ddr1, Cak, Eddr1, Mpk6
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (Protein-tyrosine kinase MPK-6) (CD167a antigen).

CNTN3_MOUSE
NC score	0.529490 (rank : 804)	θ value	9.20422e-37 (rank : 73)
Query Neighborhood Hits	2923	Target Neighborhood Hits	447	Shared Neighborhood Hits	430
SwissProt Accessions	Q07409	Gene names	Cntn3, Pang, Pcs
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

DDR1_HUMAN
NC score	0.527287 (rank : 805)	θ value	6.21693e-09 (rank : 728)
Query Neighborhood Hits	2923	Target Neighborhood Hits	819	Shared Neighborhood Hits	732
SwissProt Accessions	Q08345, Q14196, Q16562, Q5ST12, Q9UD37	Gene names	DDR1, CAK, EDDR1, RTK6, TRKE
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (TRK E) (Protein-tyrosine kinase RTK 6) (HGK2) (CD167a antigen).

CNTN6_MOUSE
NC score	0.524566 (rank : 806)	θ value	3.05695e-40 (rank : 55)
Query Neighborhood Hits	2923	Target Neighborhood Hits	429	Shared Neighborhood Hits	411
SwissProt Accessions	Q9JMB8, Q8C6X1	Gene names	Cntn6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (mNB-3).

LTK_MOUSE
NC score	0.524312 (rank : 807)	θ value	1.53129e-07 (rank : 820)
Query Neighborhood Hits	2923	Target Neighborhood Hits	770	Shared Neighborhood Hits	701
SwissProt Accessions	P08923	Gene names	Ltk
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1).

ERBB3_MOUSE
NC score	0.524135 (rank : 808)	θ value	θ > 10 (rank : 2994)
Query Neighborhood Hits	2923	Target Neighborhood Hits	898	Shared Neighborhood Hits	739
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

ALK_HUMAN
NC score	0.524131 (rank : 809)	θ value	1.29631e-06 (rank : 881)
Query Neighborhood Hits	2923	Target Neighborhood Hits	795	Shared Neighborhood Hits	698
SwissProt Accessions	Q9UM73, Q9Y4K6	Gene names	ALK
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

CNTN1_MOUSE
NC score	0.524079 (rank : 810)	θ value	6.38894e-30 (rank : 135)
Query Neighborhood Hits	2923	Target Neighborhood Hits	422	Shared Neighborhood Hits	403
SwissProt Accessions	P12960, Q6NXV7, Q8BR42, Q8C6A0	Gene names	Cntn1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3).

CNTN1_HUMAN
NC score	0.524012 (rank : 811)	θ value	4.42448e-31 (rank : 124)
Query Neighborhood Hits	2923	Target Neighborhood Hits	431	Shared Neighborhood Hits	403
SwissProt Accessions	Q12860, Q12861, Q14030, Q8N466	Gene names	CNTN1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3) (Glycoprotein gp135).

SCYL2_MOUSE
NC score	0.523462 (rank : 812)	θ value	0.000270298 (rank : 1040)
Query Neighborhood Hits	2923	Target Neighborhood Hits	603	Shared Neighborhood Hits	552
SwissProt Accessions	Q8CFE4, Q3UT57, Q3UWU9, Q8K0M4	Gene names	Scyl2, Cvak104, D10Ertd802e
Domain Architecture	No domain graphic available
Description	SCY1-like protein 2 (Coated vesicle-associated kinase of 104 kDa).

CNTN6_HUMAN
NC score	0.522938 (rank : 813)	θ value	6.37413e-38 (rank : 66)
Query Neighborhood Hits	2923	Target Neighborhood Hits	422	Shared Neighborhood Hits	409
SwissProt Accessions	Q9UQ52	Gene names	CNTN6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (hNB-3).

ALK_MOUSE
NC score	0.522881 (rank : 814)	θ value	7.59969e-07 (rank : 864)
Query Neighborhood Hits	2923	Target Neighborhood Hits	811	Shared Neighborhood Hits	712
SwissProt Accessions	P97793	Gene names	Alk
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

ERBB3_HUMAN
NC score	0.522480 (rank : 815)	θ value	θ > 10 (rank : 2993)
Query Neighborhood Hits	2923	Target Neighborhood Hits	918	Shared Neighborhood Hits	745
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

MYPN_HUMAN
NC score	0.522430 (rank : 816)	θ value	5.54529e-58 (rank : 21)
Query Neighborhood Hits	2923	Target Neighborhood Hits	418	Shared Neighborhood Hits	355
SwissProt Accessions	Q86TC9, Q5VV35, Q5VV36, Q86T37, Q8N3L4, Q96K90, Q96KF5	Gene names	MYPN, MYOP
Domain Architecture	No domain graphic available
Description	Myopalladin (145 kDa sarcomeric protein).

EPHB6_MOUSE
NC score	0.520948 (rank : 817)	θ value	7.1131e-05 (rank : 988)
Query Neighborhood Hits	2923	Target Neighborhood Hits	906	Shared Neighborhood Hits	769
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

CHL1_HUMAN
NC score	0.518586 (rank : 818)	θ value	7.80994e-28 (rank : 149)
Query Neighborhood Hits	2923	Target Neighborhood Hits	413	Shared Neighborhood Hits	390
SwissProt Accessions	O00533, Q2M3G2, Q59FY0	Gene names	CHL1, CALL
Domain Architecture	No domain graphic available
Description	Neural cell adhesion molecule L1-like protein precursor (Close homolog of L1).

IRAK2_HUMAN
NC score	0.518540 (rank : 819)	θ value	2.36792 (rank : 2064)
Query Neighborhood Hits	2923	Target Neighborhood Hits	714	Shared Neighborhood Hits	654
SwissProt Accessions	O43187	Gene names	IRAK2
Domain Architecture
Description	Interleukin-1 receptor-associated kinase-like 2 (IRAK-2).

MYPN_MOUSE
NC score	0.518493 (rank : 820)	θ value	2.7521e-57 (rank : 22)
Query Neighborhood Hits	2923	Target Neighborhood Hits	421	Shared Neighborhood Hits	338
SwissProt Accessions	Q5DTJ9, Q7TPW5, Q8BZ76	Gene names	Mypn, Kiaa4170
Domain Architecture	No domain graphic available
Description	Myopalladin.

LTK_HUMAN
NC score	0.518358 (rank : 821)	θ value	1.53129e-07 (rank : 819)
Query Neighborhood Hits	2923	Target Neighborhood Hits	774	Shared Neighborhood Hits	709
SwissProt Accessions	P29376	Gene names	LTK, TYK1
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1) (Protein tyrosine kinase 1).

CHL1_MOUSE
NC score	0.516137 (rank : 822)	θ value	2.59387e-31 (rank : 120)
Query Neighborhood Hits	2923	Target Neighborhood Hits	402	Shared Neighborhood Hits	385
SwissProt Accessions	P70232, Q8BS24, Q8C6W0, Q8C823, Q8VBY7	Gene names	Chl1, Call
Domain Architecture	No domain graphic available
Description	Neural cell adhesion molecule L1-like protein precursor (Cell adhesion molecule with homology to L1CAM) (Close homolog of L1) (Chl1-like protein).

MYOM1_MOUSE
NC score	0.515829 (rank : 823)	θ value	2.93355e-67 (rank : 16)
Query Neighborhood Hits	2923	Target Neighborhood Hits	415	Shared Neighborhood Hits	381
SwissProt Accessions	Q62234	Gene names	Myom1
Domain Architecture
Description	Myomesin-1 (Skelemin).

MYOM2_HUMAN
NC score	0.515430 (rank : 824)	θ value	1.27248e-70 (rank : 14)
Query Neighborhood Hits	2923	Target Neighborhood Hits	341	Shared Neighborhood Hits	324
SwissProt Accessions	P54296	Gene names	MYOM2
Domain Architecture
Description	Myomesin-2 (M-protein) (165 kDa titin-associated protein) (165 kDa connectin-associated protein).

KC1G2_MOUSE
NC score	0.514460 (rank : 825)	θ value	0.47712 (rank : 1610)
Query Neighborhood Hits	2923	Target Neighborhood Hits	695	Shared Neighborhood Hits	680
SwissProt Accessions	Q8BVP5	Gene names	Csnk1g2
Domain Architecture	No domain graphic available
Description	Casein kinase I isoform gamma-2 (EC 2.7.11.1) (CKI-gamma 2).

KC1G2_HUMAN
NC score	0.513629 (rank : 826)	θ value	0.21417 (rank : 1469)
Query Neighborhood Hits	2923	Target Neighborhood Hits	693	Shared Neighborhood Hits	680
SwissProt Accessions	P78368, O00704, Q8WUB1	Gene names	CSNK1G2
Domain Architecture
Description	Casein kinase I isoform gamma-2 (EC 2.7.11.1) (CKI-gamma 2).

MYOM1_HUMAN
NC score	0.513569 (rank : 827)	θ value	1.40689e-69 (rank : 15)
Query Neighborhood Hits	2923	Target Neighborhood Hits	405	Shared Neighborhood Hits	374
SwissProt Accessions	P52179	Gene names	MYOM1
Domain Architecture
Description	Myomesin-1 (190 kDa titin-associated protein) (190 kDa connectin- associated protein).

AVR2A_MOUSE
NC score	0.513566 (rank : 828)	θ value	1.81305 (rank : 1915)
Query Neighborhood Hits	2923	Target Neighborhood Hits	767	Shared Neighborhood Hits	713
SwissProt Accessions	P27038	Gene names	Acvr2a, Acvr2
Domain Architecture
Description	Activin receptor type 2A precursor (EC 2.7.11.30) (Activin receptor type IIA) (ACTR-IIA).

AVR2A_HUMAN
NC score	0.513554 (rank : 829)	θ value	1.81305 (rank : 1914)
Query Neighborhood Hits	2923	Target Neighborhood Hits	767	Shared Neighborhood Hits	713
SwissProt Accessions	P27037, Q53TH4, Q6NWV2, Q92474	Gene names	ACVR2A, ACVR2
Domain Architecture
Description	Activin receptor type 2A precursor (EC 2.7.11.30) (Activin receptor type IIA) (ACTR-IIA) (ACTRIIA).

MYOTI_HUMAN
NC score	0.513420 (rank : 830)	θ value	1.85889e-29 (rank : 140)
Query Neighborhood Hits	2923	Target Neighborhood Hits	292	Shared Neighborhood Hits	277
SwissProt Accessions	Q9UBF9	Gene names	MYOT, TTID
Domain Architecture	No domain graphic available
Description	Myotilin (Titin immunoglobulin domain protein) (Myofibrillar titin- like Ig domains protein) (57 kDa cytoskeletal protein).

MYOTI_MOUSE
NC score	0.512757 (rank : 831)	θ value	2.86786e-30 (rank : 132)
Query Neighborhood Hits	2923	Target Neighborhood Hits	297	Shared Neighborhood Hits	278
SwissProt Accessions	Q9JIF9	Gene names	Myot, Ttid
Domain Architecture	No domain graphic available
Description	Myotilin (Titin immunoglobulin domain protein) (Myofibrillar titin- like Ig domains protein).

MLKL_MOUSE
NC score	0.511839 (rank : 832)	θ value	θ > 10 (rank : 3046)
Query Neighborhood Hits	2923	Target Neighborhood Hits	707	Shared Neighborhood Hits	649
SwissProt Accessions	Q9D2Y4, Q8CIJ5	Gene names	Mlkl
Domain Architecture	No domain graphic available
Description	Mixed lineage kinase domain-like protein.

EPHB6_HUMAN
NC score	0.511224 (rank : 833)	θ value	1.09739e-05 (rank : 931)
Query Neighborhood Hits	2923	Target Neighborhood Hits	912	Shared Neighborhood Hits	754
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

MYPC1_HUMAN
NC score	0.510480 (rank : 834)	θ value	1.22964e-73 (rank : 12)
Query Neighborhood Hits	2923	Target Neighborhood Hits	303	Shared Neighborhood Hits	289
SwissProt Accessions	Q00872, Q15497	Gene names	MYBPC1, MYBPCS
Domain Architecture
Description	Myosin-binding protein C, slow-type (Slow MyBP-C) (C-protein, skeletal muscle slow isoform).

TGFR2_MOUSE
NC score	0.509012 (rank : 835)	θ value	8.99809 (rank : 2899)
Query Neighborhood Hits	2923	Target Neighborhood Hits	748	Shared Neighborhood Hits	694
SwissProt Accessions	Q62312, Q63947	Gene names	Tgfbr2
Domain Architecture
Description	TGF-beta receptor type-2 precursor (EC 2.7.11.30) (TGF-beta receptor type II) (TGFR-2) (TGF-beta type II receptor).

TGFR2_HUMAN
NC score	0.508562 (rank : 836)	θ value	θ > 10 (rank : 3115)
Query Neighborhood Hits	2923	Target Neighborhood Hits	748	Shared Neighborhood Hits	693
SwissProt Accessions	P37173, Q15580, Q6DKT6, Q99474	Gene names	TGFBR2
Domain Architecture
Description	TGF-beta receptor type-2 precursor (EC 2.7.11.30) (TGF-beta receptor type II) (TGFR-2) (TGF-beta type II receptor).

MYPC2_HUMAN
NC score	0.505363 (rank : 837)	θ value	9.41505e-74 (rank : 11)
Query Neighborhood Hits	2923	Target Neighborhood Hits	316	Shared Neighborhood Hits	303
SwissProt Accessions	Q14324	Gene names	MYBPC2, MYBPCF
Domain Architecture
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

ACVR1_MOUSE
NC score	0.503617 (rank : 838)	θ value	θ > 10 (rank : 2933)
Query Neighborhood Hits	2923	Target Neighborhood Hits	768	Shared Neighborhood Hits	714
SwissProt Accessions	P37172, Q3UDH5, Q91VF1	Gene names	Acvr1, Acvrlk2, Tgfb1
Domain Architecture
Description	Activin receptor type-1 precursor (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) (Serine/threonine-protein kinase receptor R1) (SKR1) (TGF-B superfamily receptor type I) (TSR-I) (TSK-7L).

MYPC2_MOUSE
NC score	0.503310 (rank : 839)	θ value	4.99229e-75 (rank : 10)
Query Neighborhood Hits	2923	Target Neighborhood Hits	297	Shared Neighborhood Hits	282
SwissProt Accessions	Q5XKE0, Q8C109, Q8K2V0	Gene names	Mybpc2
Domain Architecture	No domain graphic available
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

MYPC3_MOUSE
NC score	0.499702 (rank : 840)	θ value	8.20983e-86 (rank : 7)
Query Neighborhood Hits	2923	Target Neighborhood Hits	310	Shared Neighborhood Hits	295
SwissProt Accessions	O70468, O88997	Gene names	Mybpc3
Domain Architecture
Description	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform).

MYPC3_HUMAN
NC score	0.499067 (rank : 841)	θ value	7.45998e-71 (rank : 13)
Query Neighborhood Hits	2923	Target Neighborhood Hits	318	Shared Neighborhood Hits	300
SwissProt Accessions	Q14896, Q16410, Q6R2F7, Q9UE27, Q9UM53	Gene names	MYBPC3
Domain Architecture
Description	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform).

AVR2B_HUMAN
NC score	0.498071 (rank : 842)	θ value	θ > 10 (rank : 2946)
Query Neighborhood Hits	2923	Target Neighborhood Hits	748	Shared Neighborhood Hits	697
SwissProt Accessions	Q13705, Q4VAV0	Gene names	ACVR2B
Domain Architecture
Description	Activin receptor type 2B precursor (EC 2.7.11.30) (Activin receptor type IIB) (ACTR-IIB).

EPHAA_HUMAN
NC score	0.498063 (rank : 843)	θ value	1.29631e-06 (rank : 883)
Query Neighborhood Hits	2923	Target Neighborhood Hits	960	Shared Neighborhood Hits	770
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

ACVR1_HUMAN
NC score	0.497977 (rank : 844)	θ value	θ > 10 (rank : 2932)
Query Neighborhood Hits	2923	Target Neighborhood Hits	760	Shared Neighborhood Hits	709
SwissProt Accessions	Q04771	Gene names	ACVR1, ACVRLK2
Domain Architecture
Description	Activin receptor type-1 precursor (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) (Serine/threonine-protein kinase receptor R1) (SKR1) (Activin receptor-like kinase 2) (ALK-2) (TGF-B superfamily receptor type I) (TSR-I).

AVR2B_MOUSE
NC score	0.497934 (rank : 845)	θ value	θ > 10 (rank : 2947)
Query Neighborhood Hits	2923	Target Neighborhood Hits	749	Shared Neighborhood Hits	697
SwissProt Accessions	P27040	Gene names	Acvr2b
Domain Architecture
Description	Activin receptor type 2B precursor (EC 2.7.11.30) (Activin receptor type IIB) (ACTR-IIB).

FGRL1_HUMAN
NC score	0.496295 (rank : 846)	θ value	1.92812e-18 (rank : 304)
Query Neighborhood Hits	2923	Target Neighborhood Hits	335	Shared Neighborhood Hits	310
SwissProt Accessions	Q8N441, Q6PJN1, Q9BXN7, Q9H4D7	Gene names	FGFRL1, FGFR5, FHFR
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5) (FGFR-like protein) (FGF homologous factor receptor).

LSAMP_HUMAN
NC score	0.494779 (rank : 847)	θ value	1.63225e-17 (rank : 343)
Query Neighborhood Hits	2923	Target Neighborhood Hits	347	Shared Neighborhood Hits	339
SwissProt Accessions	Q13449, Q8IV49	Gene names	LSAMP, LAMP
Domain Architecture
Description	Limbic system-associated membrane protein precursor (LSAMP).

LSAMP_MOUSE
NC score	0.494641 (rank : 848)	θ value	5.60996e-18 (rank : 328)
Query Neighborhood Hits	2923	Target Neighborhood Hits	344	Shared Neighborhood Hits	336
SwissProt Accessions	Q8BLK3	Gene names	Lsamp
Domain Architecture	No domain graphic available
Description	Limbic system-associated membrane protein precursor (LSAMP).

IRAK3_MOUSE
NC score	0.494321 (rank : 849)	θ value	0.00102713 (rank : 1082)
Query Neighborhood Hits	2923	Target Neighborhood Hits	628	Shared Neighborhood Hits	563
SwissProt Accessions	Q8K4B2, Q8C7U8, Q8CE40, Q8K1S8	Gene names	Irak3
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1) (IRAK-3) (IL- 1 receptor-associated kinase M) (IRAK-M).

FGRL1_MOUSE
NC score	0.494183 (rank : 850)	θ value	2.5182e-18 (rank : 310)
Query Neighborhood Hits	2923	Target Neighborhood Hits	325	Shared Neighborhood Hits	311
SwissProt Accessions	Q91V87, Q920C2, Q920C3	Gene names	Fgfrl1, Fgfr5
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5).

BMR1A_HUMAN
NC score	0.492510 (rank : 851)	θ value	θ > 10 (rank : 2952)
Query Neighborhood Hits	2923	Target Neighborhood Hits	759	Shared Neighborhood Hits	700
SwissProt Accessions	P36894, Q8NEN8	Gene names	BMPR1A, ACVRLK3, ALK3
Domain Architecture
Description	Bone morphogenetic protein receptor type IA precursor (EC 2.7.11.30) (Serine/threonine-protein kinase receptor R5) (SKR5) (Activin receptor-like kinase 3) (ALK-3) (CD292 antigen).

NPHN_HUMAN
NC score	0.492496 (rank : 852)	θ value	5.23862e-24 (rank : 192)
Query Neighborhood Hits	2923	Target Neighborhood Hits	362	Shared Neighborhood Hits	337
SwissProt Accessions	O60500	Gene names	NPHS1, NPHN
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

IRAK3_HUMAN
NC score	0.492142 (rank : 853)	θ value	0.125558 (rank : 1391)
Query Neighborhood Hits	2923	Target Neighborhood Hits	644	Shared Neighborhood Hits	586
SwissProt Accessions	Q9Y616	Gene names	IRAK3
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1) (IRAK-3) (IL- 1 receptor-associated kinase M) (IRAK-M).

MAMC1_HUMAN
NC score	0.491682 (rank : 854)	θ value	5.97985e-28 (rank : 148)
Query Neighborhood Hits	2923	Target Neighborhood Hits	357	Shared Neighborhood Hits	328
SwissProt Accessions	Q7Z553	Gene names	MAMDC1, MDGA2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

BMR1A_MOUSE
NC score	0.491569 (rank : 855)	θ value	θ > 10 (rank : 2953)
Query Neighborhood Hits	2923	Target Neighborhood Hits	758	Shared Neighborhood Hits	700
SwissProt Accessions	P36895	Gene names	Bmpr1a, Acvrlk3, Bmpr
Domain Architecture
Description	Bone morphogenetic protein receptor type IA precursor (EC 2.7.11.30) (Serine/threonine-protein kinase receptor R5) (SKR5) (Activin receptor-like kinase 3) (ALK-3) (BMP-2/BMP-4 receptor).

MAMC1_MOUSE
NC score	0.490194 (rank : 856)	θ value	7.80994e-28 (rank : 150)
Query Neighborhood Hits	2923	Target Neighborhood Hits	357	Shared Neighborhood Hits	327
SwissProt Accessions	P60755	Gene names	Mamdc1, Mdga2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

OPCM_HUMAN
NC score	0.489917 (rank : 857)	θ value	4.58923e-20 (rank : 269)
Query Neighborhood Hits	2923	Target Neighborhood Hits	332	Shared Neighborhood Hits	324
SwissProt Accessions	Q14982	Gene names	OPCML, OBCAM
Domain Architecture
Description	Opioid-binding protein/cell adhesion molecule precursor (OBCAM) (Opioid-binding cell adhesion molecule) (OPCML).

ANKK1_MOUSE
NC score	0.489842 (rank : 858)	θ value	θ > 10 (rank : 2941)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1072	Shared Neighborhood Hits	769
SwissProt Accessions	Q8BZ25	Gene names	Ankk1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1).

NPHN_MOUSE
NC score	0.489597 (rank : 859)	θ value	5.59698e-26 (rank : 164)
Query Neighborhood Hits	2923	Target Neighborhood Hits	370	Shared Neighborhood Hits	345
SwissProt Accessions	Q9QZS7	Gene names	Nphs1, Nphn
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

NTRI_MOUSE
NC score	0.489139 (rank : 860)	θ value	1.33526e-19 (rank : 278)
Query Neighborhood Hits	2923	Target Neighborhood Hits	342	Shared Neighborhood Hits	334
SwissProt Accessions	Q99PJ0	Gene names	Nt, Hnt
Domain Architecture
Description	Neurotrimin precursor.

NTRI_HUMAN
NC score	0.487882 (rank : 861)	θ value	3.51386e-20 (rank : 261)
Query Neighborhood Hits	2923	Target Neighborhood Hits	344	Shared Neighborhood Hits	335
SwissProt Accessions	Q9P121, Q6UXJ3, Q86VJ9	Gene names	NT
Domain Architecture
Description	Neurotrimin precursor (hNT).

BUB1_MOUSE
NC score	0.486462 (rank : 862)	θ value	3.0926 (rank : 2135)
Query Neighborhood Hits	2923	Target Neighborhood Hits	583	Shared Neighborhood Hits	548
SwissProt Accessions	O08901, O09007	Gene names	Bub1
Domain Architecture
Description	Mitotic checkpoint serine/threonine-protein kinase BUB1 (EC 2.7.11.1) (MBUB1) (BUB1A).

MDGA1_HUMAN
NC score	0.484758 (rank : 863)	θ value	7.30988e-26 (rank : 165)
Query Neighborhood Hits	2923	Target Neighborhood Hits	358	Shared Neighborhood Hits	332
SwissProt Accessions	Q8NFP4, Q8NBE3	Gene names	MDGA1, MAMDC3
Domain Architecture
Description	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 precursor (MAM domain-containing protein 3) (GPI and MAM protein) (Glycosylphosphatidylinositol-MAM) (GPIM).

NEGR1_HUMAN
NC score	0.484361 (rank : 864)	θ value	1.29331e-14 (rank : 427)
Query Neighborhood Hits	2923	Target Neighborhood Hits	346	Shared Neighborhood Hits	337
SwissProt Accessions	Q7Z3B1, Q5VT21, Q6UY06, Q8NAQ3	Gene names	NEGR1
Domain Architecture	No domain graphic available
Description	Neuronal growth regulator 1 precursor.

TGFR1_HUMAN
NC score	0.483503 (rank : 865)	θ value	θ > 10 (rank : 3113)
Query Neighborhood Hits	2923	Target Neighborhood Hits	755	Shared Neighborhood Hits	704
SwissProt Accessions	P36897	Gene names	TGFBR1
Domain Architecture
Description	TGF-beta receptor type-1 precursor (EC 2.7.11.30) (TGF-beta receptor type I) (TGFR-1) (TGF-beta type I receptor) (Serine/threonine-protein kinase receptor R4) (SKR4) (Activin receptor-like kinase 5) (ALK-5).

TGFR1_MOUSE
NC score	0.483282 (rank : 866)	θ value	θ > 10 (rank : 3114)
Query Neighborhood Hits	2923	Target Neighborhood Hits	753	Shared Neighborhood Hits	704
SwissProt Accessions	Q64729	Gene names	Tgfbr1
Domain Architecture
Description	TGF-beta receptor type-1 precursor (EC 2.7.11.30) (TGF-beta receptor type I) (TGFR-1) (TGF-beta type I receptor) (ESK2).

SN_MOUSE
NC score	0.482356 (rank : 867)	θ value	4.11246e-53 (rank : 34)
Query Neighborhood Hits	2923	Target Neighborhood Hits	416	Shared Neighborhood Hits	364
SwissProt Accessions	Q62230, O55216, Q62228, Q62229	Gene names	Sn, Sa
Domain Architecture
Description	Sialoadhesin precursor (Sialic acid-binding Ig-like lectin-1) (Siglec- 1) (Sheep erythrocyte receptor) (SER) (CD169 antigen).

NEGR1_MOUSE
NC score	0.481736 (rank : 868)	θ value	1.86753e-13 (rank : 482)
Query Neighborhood Hits	2923	Target Neighborhood Hits	349	Shared Neighborhood Hits	337
SwissProt Accessions	Q80Z24, Q3UHQ8, Q80T70	Gene names	Negr1, Kiaa3001, Ntra
Domain Architecture	No domain graphic available
Description	Neuronal growth regulator 1 precursor (Kilon protein) (Kindred of IgLON) (Neurotractin).

ANKK1_HUMAN
NC score	0.480684 (rank : 869)	θ value	θ > 10 (rank : 2940)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1075	Shared Neighborhood Hits	765
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

BMR1B_MOUSE
NC score	0.480082 (rank : 870)	θ value	θ > 10 (rank : 2955)
Query Neighborhood Hits	2923	Target Neighborhood Hits	758	Shared Neighborhood Hits	703
SwissProt Accessions	P36898, Q3TRF2	Gene names	Bmpr1b, Acvrlk6
Domain Architecture
Description	Bone morphogenetic protein receptor type IB precursor (EC 2.7.11.30) (Serine/threonine-protein kinase receptor R6) (SKR6) (Activin receptor-like kinase 6) (ALK-6).

VCAM1_HUMAN
NC score	0.479537 (rank : 871)	θ value	1.09232e-21 (rank : 230)
Query Neighborhood Hits	2923	Target Neighborhood Hits	352	Shared Neighborhood Hits	313
SwissProt Accessions	P19320, Q6NUP8	Gene names	VCAM1, L1CAM
Domain Architecture
Description	Vascular cell adhesion protein 1 precursor (V-CAM 1) (CD106 antigen) (INCAM-100).

ACV1B_MOUSE
NC score	0.478927 (rank : 872)	θ value	θ > 10 (rank : 2927)
Query Neighborhood Hits	2923	Target Neighborhood Hits	753	Shared Neighborhood Hits	700
SwissProt Accessions	Q61271	Gene names	Acvr1b
Domain Architecture
Description	Activin receptor type 1B precursor (EC 2.7.11.30) (ACTR-IB) (Serine/threonine-protein kinase receptor R2) (SKR2).

BMR1B_HUMAN
NC score	0.478891 (rank : 873)	θ value	θ > 10 (rank : 2954)
Query Neighborhood Hits	2923	Target Neighborhood Hits	760	Shared Neighborhood Hits	703
SwissProt Accessions	O00238, P78366	Gene names	BMPR1B
Domain Architecture
Description	Bone morphogenetic protein receptor type IB precursor (EC 2.7.11.30) (CDw293 antigen).

VCAM1_MOUSE
NC score	0.478554 (rank : 874)	θ value	5.79196e-23 (rank : 205)
Query Neighborhood Hits	2923	Target Neighborhood Hits	320	Shared Neighborhood Hits	300
SwissProt Accessions	P29533	Gene names	Vcam1, Vcam-1
Domain Architecture
Description	Vascular cell adhesion protein 1 precursor (V-CAM 1).

ACV1B_HUMAN
NC score	0.478535 (rank : 875)	θ value	θ > 10 (rank : 2926)
Query Neighborhood Hits	2923	Target Neighborhood Hits	753	Shared Neighborhood Hits	701
SwissProt Accessions	P36896, Q15479, Q15480, Q15481, Q15482	Gene names	ACVR1B, ACVRLK4
Domain Architecture
Description	Activin receptor type 1B precursor (EC 2.7.11.30) (ACTR-IB) (Serine/threonine-protein kinase receptor R2) (SKR2) (Activin receptor-like kinase 4) (ALK-4).

SN_HUMAN
NC score	0.478313 (rank : 876)	θ value	4.70527e-49 (rank : 37)
Query Neighborhood Hits	2923	Target Neighborhood Hits	434	Shared Neighborhood Hits	377
SwissProt Accessions	Q9BZZ2, Q96DL4, Q9GZS5, Q9H1H6, Q9H1H7, Q9H7L7	Gene names	SN
Domain Architecture
Description	Sialoadhesin precursor (Sialic acid-binding Ig-like lectin-1) (Siglec- 1) (CD169 antigen).

TOPK_MOUSE
NC score	0.478238 (rank : 877)	θ value	1.81305 (rank : 1997)
Query Neighborhood Hits	2923	Target Neighborhood Hits	618	Shared Neighborhood Hits	559
SwissProt Accessions	Q9JJ78, Q922V2, Q9D184	Gene names	Pbk, Topk
Domain Architecture	No domain graphic available
Description	T-lymphokine-activated killer cell-originated protein kinase (EC 2.7.12.2) (T-LAK cell-originated protein kinase) (PDZ-binding kinase).

RIPK4_HUMAN
NC score	0.477783 (rank : 878)	θ value	θ > 10 (rank : 3086)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1094	Shared Neighborhood Hits	776
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

ROBO4_MOUSE
NC score	0.474904 (rank : 879)	θ value	7.84624e-12 (rank : 560)
Query Neighborhood Hits	2923	Target Neighborhood Hits	358	Shared Neighborhood Hits	310
SwissProt Accessions	Q8C310, Q9DBW1	Gene names	Robo4
Domain Architecture
Description	Roundabout homolog 4 precursor.

TOPK_HUMAN
NC score	0.473467 (rank : 880)	θ value	0.813845 (rank : 1755)
Query Neighborhood Hits	2923	Target Neighborhood Hits	605	Shared Neighborhood Hits	545
SwissProt Accessions	Q96KB5, Q9NPD9, Q9NYL7, Q9NZK6	Gene names	PBK, TOPK
Domain Architecture	No domain graphic available
Description	T-lymphokine-activated killer cell-originated protein kinase (EC 2.7.12.2) (T-LAK cell-originated protein kinase) (PDZ-binding kinase) (Spermatogenesis-related protein kinase) (SPK) (MAPKK-like protein kinase) (Nori-3).

RYK_MOUSE
NC score	0.471303 (rank : 881)	θ value	0.0431538 (rank : 1294)
Query Neighborhood Hits	2923	Target Neighborhood Hits	715	Shared Neighborhood Hits	663
SwissProt Accessions	Q01887, Q61890	Gene names	Ryk, Mrk
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1) (Kinase VIK) (NYK- R) (Met-related kinase).

ROBO4_HUMAN
NC score	0.470465 (rank : 882)	θ value	3.52202e-12 (rank : 542)
Query Neighborhood Hits	2923	Target Neighborhood Hits	364	Shared Neighborhood Hits	322
SwissProt Accessions	Q8WZ75, Q8TEG1, Q96JV6, Q9H718, Q9NWJ8	Gene names	ROBO4
Domain Architecture
Description	Roundabout homolog 4 precursor (Magic roundabout).

ACVL1_MOUSE
NC score	0.466384 (rank : 883)	θ value	θ > 10 (rank : 2931)
Query Neighborhood Hits	2923	Target Neighborhood Hits	739	Shared Neighborhood Hits	689
SwissProt Accessions	Q61288, Q61289	Gene names	Acvrl1, Acvrlk1, Alk-1
Domain Architecture
Description	Serine/threonine-protein kinase receptor R3 precursor (EC 2.7.11.30) (SKR3) (Activin receptor-like kinase 1) (ALK-1) (TGF-B superfamily receptor type I) (TSR-I).

SRPK2_MOUSE
NC score	0.465553 (rank : 884)	θ value	0.000461057 (rank : 1058)
Query Neighborhood Hits	2923	Target Neighborhood Hits	765	Shared Neighborhood Hits	664
SwissProt Accessions	O54781, Q8VCD9	Gene names	Srpk2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SRPK2 (EC 2.7.11.1) (Serine/arginine- rich protein-specific kinase 2) (SR-protein-specific kinase 2) (SFRS protein kinase 2).

BMPR2_HUMAN
NC score	0.464240 (rank : 885)	θ value	θ > 10 (rank : 2950)
Query Neighborhood Hits	2923	Target Neighborhood Hits	736	Shared Neighborhood Hits	667
SwissProt Accessions	Q13873, Q16569	Gene names	BMPR2, PPH1
Domain Architecture
Description	Bone morphogenetic protein receptor type-2 precursor (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II).

CD22_HUMAN
NC score	0.463989 (rank : 886)	θ value	4.73814e-25 (rank : 173)
Query Neighborhood Hits	2923	Target Neighborhood Hits	365	Shared Neighborhood Hits	323
SwissProt Accessions	P20273, O95699, O95701, O95702, O95703, Q01665, Q92872, Q92873, Q9UQA6, Q9UQA7, Q9UQA8, Q9UQA9, Q9UQB0, Q9Y2A6	Gene names	CD22
Domain Architecture
Description	B-cell receptor CD22 precursor (Leu-14) (B-lymphocyte cell adhesion molecule) (BL-CAM) (Siglec-2).

SRPK2_HUMAN
NC score	0.463829 (rank : 887)	θ value	0.000461057 (rank : 1057)
Query Neighborhood Hits	2923	Target Neighborhood Hits	664	Shared Neighborhood Hits	600
SwissProt Accessions	P78362, O75220, O75221, Q6NUL0, Q6V1X2, Q8IYQ3	Gene names	SRPK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SRPK2 (EC 2.7.11.1) (Serine/arginine- rich protein-specific kinase 2) (SR-protein-specific kinase 2) (SFRS protein kinase 2).

BMPR2_MOUSE
NC score	0.462871 (rank : 888)	θ value	θ > 10 (rank : 2951)
Query Neighborhood Hits	2923	Target Neighborhood Hits	738	Shared Neighborhood Hits	666
SwissProt Accessions	O35607	Gene names	Bmpr2
Domain Architecture
Description	Bone morphogenetic protein receptor type-2 precursor (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II) (BRK-3).

STK23_HUMAN
NC score	0.460883 (rank : 889)	θ value	0.00509761 (rank : 1160)
Query Neighborhood Hits	2923	Target Neighborhood Hits	556	Shared Neighborhood Hits	548
SwissProt Accessions	Q9UPE1, Q13583, Q9UM62	Gene names	STK23, MSSK1
Domain Architecture
Description	Serine/threonine-protein kinase 23 (EC 2.7.11.1) (Muscle-specific serine kinase 1) (MSSK-1).

STK23_MOUSE
NC score	0.460821 (rank : 890)	θ value	0.00509761 (rank : 1161)
Query Neighborhood Hits	2923	Target Neighborhood Hits	572	Shared Neighborhood Hits	555
SwissProt Accessions	Q9Z0G2	Gene names	Stk23, Mssk1
Domain Architecture
Description	Serine/threonine-protein kinase 23 (EC 2.7.11.1) (Muscle-specific serine kinase 1) (MSSK-1).

SRPK1_HUMAN
NC score	0.460586 (rank : 891)	θ value	0.163984 (rank : 1435)
Query Neighborhood Hits	2923	Target Neighborhood Hits	706	Shared Neighborhood Hits	616
SwissProt Accessions	Q96SB4, Q12890, Q5R364, Q5R365, Q8IY12	Gene names	SRPK1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SRPK1 (EC 2.7.11.1) (Serine/arginine- rich protein-specific kinase 1) (SR-protein-specific kinase 1) (SFRS protein kinase 1).

RYK_HUMAN
NC score	0.460527 (rank : 892)	θ value	0.00869519 (rank : 1189)
Query Neighborhood Hits	2923	Target Neighborhood Hits	701	Shared Neighborhood Hits	652
SwissProt Accessions	P34925, Q04696	Gene names	RYK, JTK5A
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1).

SRPK1_MOUSE
NC score	0.460376 (rank : 893)	θ value	0.125558 (rank : 1402)
Query Neighborhood Hits	2923	Target Neighborhood Hits	639	Shared Neighborhood Hits	579
SwissProt Accessions	O70551, O70193, Q99JT3	Gene names	Srpk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SRPK1 (EC 2.7.11.1) (Serine/arginine- rich protein-specific kinase 1) (SR-protein-specific kinase 1) (SFRS protein kinase 1).

MYBPH_MOUSE
NC score	0.459577 (rank : 894)	θ value	1.51715e-39 (rank : 58)
Query Neighborhood Hits	2923	Target Neighborhood Hits	290	Shared Neighborhood Hits	260
SwissProt Accessions	P70402	Gene names	Mybph
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

CD22_MOUSE
NC score	0.459307 (rank : 895)	θ value	1.99067e-23 (rank : 199)
Query Neighborhood Hits	2923	Target Neighborhood Hits	331	Shared Neighborhood Hits	296
SwissProt Accessions	P35329, Q9JHL2, Q9JJX9, Q9JJY0, Q9JJY1, Q9R056, Q9R094, Q9WU51	Gene names	Cd22, Lyb-8
Domain Architecture
Description	B-cell receptor CD22 precursor (Leu-14) (B-lymphocyte cell adhesion molecule) (BL-CAM) (Siglec-2).

MYBPH_HUMAN
NC score	0.458358 (rank : 896)	θ value	1.08726e-37 (rank : 68)
Query Neighborhood Hits	2923	Target Neighborhood Hits	256	Shared Neighborhood Hits	249
SwissProt Accessions	Q13203, Q16886, Q86YC5	Gene names	MYBPH
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

MAG_HUMAN
NC score	0.454189 (rank : 897)	θ value	2.69671e-12 (rank : 536)
Query Neighborhood Hits	2923	Target Neighborhood Hits	278	Shared Neighborhood Hits	269
SwissProt Accessions	P20916	Gene names	MAG
Domain Architecture
Description	Myelin-associated glycoprotein precursor (Siglec-4a).

MAG_MOUSE
NC score	0.453748 (rank : 898)	θ value	6.00763e-12 (rank : 552)
Query Neighborhood Hits	2923	Target Neighborhood Hits	271	Shared Neighborhood Hits	262
SwissProt Accessions	P20917, P16880	Gene names	Mag
Domain Architecture
Description	Myelin-associated glycoprotein precursor (Siglec-4a).

KIRR2_HUMAN
NC score	0.449615 (rank : 899)	θ value	5.25075e-16 (rank : 379)
Query Neighborhood Hits	2923	Target Neighborhood Hits	321	Shared Neighborhood Hits	298
SwissProt Accessions	Q6UWL6, Q6P1R1, Q7Z5P1, Q7Z5P2, Q96IQ8, Q9H0T1	Gene names	KIRREL2, NEPH3
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2) (Nephrin-like protein 3).

ACVL1_HUMAN
NC score	0.449502 (rank : 900)	θ value	θ > 10 (rank : 2930)
Query Neighborhood Hits	2923	Target Neighborhood Hits	716	Shared Neighborhood Hits	665
SwissProt Accessions	P37023	Gene names	ACVRL1, ACVRLK1, ALK1
Domain Architecture
Description	Serine/threonine-protein kinase receptor R3 precursor (EC 2.7.11.30) (SKR3) (Activin receptor-like kinase 1) (ALK-1) (TGF-B superfamily receptor type I) (TSR-I).

KIRR2_MOUSE
NC score	0.445180 (rank : 901)	θ value	9.56915e-18 (rank : 335)
Query Neighborhood Hits	2923	Target Neighborhood Hits	326	Shared Neighborhood Hits	295
SwissProt Accessions	Q7TSU7, Q7TQ98	Gene names	Kirrel2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2).

LU_HUMAN
NC score	0.440216 (rank : 902)	θ value	2.36244e-08 (rank : 761)
Query Neighborhood Hits	2923	Target Neighborhood Hits	283	Shared Neighborhood Hits	266
SwissProt Accessions	P50895, Q86VC7	Gene names	BCAM, LU, MSK19
Domain Architecture
Description	Lutheran blood group glycoprotein precursor (B-CAM cell surface glycoprotein) (Auberger B antigen) (F8/G253 antigen) (CD239 antigen).

TMIGD_HUMAN
NC score	0.433359 (rank : 903)	θ value	1.69304e-06 (rank : 893)
Query Neighborhood Hits	2923	Target Neighborhood Hits	240	Shared Neighborhood Hits	234
SwissProt Accessions	Q6UXZ0, Q6ZMC6	Gene names	TMIGD
Domain Architecture	No domain graphic available
Description	Transmembrane and immunoglobulin domain-containing protein precursor.

JAM1_HUMAN
NC score	0.433176 (rank : 904)	θ value	5.08577e-11 (rank : 595)
Query Neighborhood Hits	2923	Target Neighborhood Hits	294	Shared Neighborhood Hits	280
SwissProt Accessions	Q9Y624	Gene names	F11R, JAM1, JCAM
Domain Architecture
Description	Junctional adhesion molecule A precursor (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (Platelet adhesion molecule 1) (PAM-1) (Platelet F11 receptor) (CD321 antigen).

MLKL_HUMAN
NC score	0.432874 (rank : 905)	θ value	θ > 10 (rank : 3045)
Query Neighborhood Hits	2923	Target Neighborhood Hits	600	Shared Neighborhood Hits	544
SwissProt Accessions	Q8NB16, Q8N6V0	Gene names	MLKL
Domain Architecture	No domain graphic available
Description	Mixed lineage kinase domain-like protein.

KIRR1_HUMAN
NC score	0.432821 (rank : 906)	θ value	8.36355e-22 (rank : 224)
Query Neighborhood Hits	2923	Target Neighborhood Hits	401	Shared Neighborhood Hits	332
SwissProt Accessions	Q96J84, Q5XKC6, Q7Z696, Q7Z7N8, Q8TB15, Q9H9N1, Q9NVA5	Gene names	KIRREL, NEPH1
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 1 precursor (Kin of irregular chiasm-like protein 1) (Nephrin-like protein 1).

KIRR3_HUMAN
NC score	0.430132 (rank : 907)	θ value	1.47631e-18 (rank : 303)
Query Neighborhood Hits	2923	Target Neighborhood Hits	302	Shared Neighborhood Hits	278
SwissProt Accessions	Q8IZU9, Q6UWJ9, Q6UWL5, Q96JG0	Gene names	KIRREL3, KIAA1867, NEPH2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 3 precursor (Kin of irregular chiasm-like protein 3) (Nephrin-like 2).

ACV1C_MOUSE
NC score	0.429876 (rank : 908)	θ value	θ > 10 (rank : 2929)
Query Neighborhood Hits	2923	Target Neighborhood Hits	715	Shared Neighborhood Hits	655
SwissProt Accessions	Q8K348	Gene names	Acvr1c, Alk7
Domain Architecture	No domain graphic available
Description	Activin receptor type 1C precursor (EC 2.7.11.30) (ACTR-IC) (Activin receptor-like kinase 7) (ALK-7).

KIRR1_MOUSE
NC score	0.429438 (rank : 909)	θ value	2.87452e-22 (rank : 217)
Query Neighborhood Hits	2923	Target Neighborhood Hits	403	Shared Neighborhood Hits	333
SwissProt Accessions	Q80W68, Q8CIJ4, Q8CJ59, Q923L4	Gene names	Kirrel1, Kirrel, Neph1
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 1 precursor (Kin of irregular chiasm-like protein 1) (Nephrin-like protein 1).

PTPRD_MOUSE
NC score	0.428986 (rank : 910)	θ value	7.04741e-37 (rank : 72)
Query Neighborhood Hits	2923	Target Neighborhood Hits	491	Shared Neighborhood Hits	410
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRF_HUMAN
NC score	0.428483 (rank : 911)	θ value	5.584e-34 (rank : 102)
Query Neighborhood Hits	2923	Target Neighborhood Hits	489	Shared Neighborhood Hits	418
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

ACV1C_HUMAN
NC score	0.427260 (rank : 912)	θ value	θ > 10 (rank : 2928)
Query Neighborhood Hits	2923	Target Neighborhood Hits	709	Shared Neighborhood Hits	649
SwissProt Accessions	Q8NER5, Q4ZFZ8, Q86UL1, Q86UL2, Q8TBG2	Gene names	ACVR1C, ALK7
Domain Architecture	No domain graphic available
Description	Activin receptor type 1C precursor (EC 2.7.11.30) (ACTR-IC) (Activin receptor-like kinase 7) (ALK-7).

KIRR3_MOUSE
NC score	0.426490 (rank : 913)	θ value	2.5182e-18 (rank : 313)
Query Neighborhood Hits	2923	Target Neighborhood Hits	292	Shared Neighborhood Hits	268
SwissProt Accessions	Q8BR86, Q6P555, Q810H3, Q8BGQ5, Q8BRS8	Gene names	Kirrel3, Kiaa1867
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 3 precursor (Kin of irregular chiasm-like protein 3).

CEAM5_HUMAN
NC score	0.426436 (rank : 914)	θ value	8.08199e-25 (rank : 180)
Query Neighborhood Hits	2923	Target Neighborhood Hits	343	Shared Neighborhood Hits	320
SwissProt Accessions	P06731	Gene names	CEACAM5, CEA
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 5 precursor (Carcinoembryonic antigen) (CEA) (Meconium antigen 100) (CD66e antigen).

MALT1_HUMAN
NC score	0.426306 (rank : 915)	θ value	8.97725e-08 (rank : 795)
Query Neighborhood Hits	2923	Target Neighborhood Hits	236	Shared Neighborhood Hits	227
SwissProt Accessions	Q9UDY8, Q9NTB7, Q9ULX4	Gene names	MALT1, MLT
Domain Architecture
Description	Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (EC 3.4.22.-) (MALT lymphoma-associated translocation) (Paracaspase).

RAGE_HUMAN
NC score	0.424616 (rank : 916)	θ value	7.1131e-05 (rank : 991)
Query Neighborhood Hits	2923	Target Neighborhood Hits	269	Shared Neighborhood Hits	260
SwissProt Accessions	Q15109, Q15279, Q9H2X7, Q9Y3R3	Gene names	AGER, RAGE
Domain Architecture
Description	Advanced glycosylation end product-specific receptor precursor (Receptor for advanced glycosylation end products).

FSTL4_HUMAN
NC score	0.423125 (rank : 917)	θ value	9.26847e-13 (rank : 505)
Query Neighborhood Hits	2923	Target Neighborhood Hits	344	Shared Neighborhood Hits	275
SwissProt Accessions	Q6MZW2, Q8TBU0, Q9UPU1	Gene names	FSTL4, KIAA1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4).

JAM1_MOUSE
NC score	0.420000 (rank : 918)	θ value	5.62301e-10 (rank : 655)
Query Neighborhood Hits	2923	Target Neighborhood Hits	287	Shared Neighborhood Hits	275
SwissProt Accessions	O88792	Gene names	F11r, Jam1, Jcam, Jcam1
Domain Architecture
Description	Junctional adhesion molecule A precursor (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (CD321 antigen).

PTPRD_HUMAN
NC score	0.419731 (rank : 919)	θ value	3.05695e-40 (rank : 56)
Query Neighborhood Hits	2923	Target Neighborhood Hits	485	Shared Neighborhood Hits	400
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

MUC18_HUMAN
NC score	0.419615 (rank : 920)	θ value	1.74796e-11 (rank : 572)
Query Neighborhood Hits	2923	Target Neighborhood Hits	275	Shared Neighborhood Hits	258
SwissProt Accessions	P43121, O95812, Q59E86, Q6PHR3, Q6ZTR2	Gene names	MCAM, MUC18
Domain Architecture
Description	Cell surface glycoprotein MUC18 precursor (Melanoma-associated antigen MUC18) (Melanoma cell adhesion molecule) (Melanoma-associated antigen A32) (S-endo 1 endothelial-associated antigen) (Cell surface glycoprotein P1H12) (CD146 antigen).

HMCN1_HUMAN
NC score	0.418776 (rank : 921)	θ value	0 (rank : 1)
Query Neighborhood Hits	2923	Target Neighborhood Hits	983	Shared Neighborhood Hits	538
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

ICAM5_MOUSE
NC score	0.418010 (rank : 922)	θ value	6.41864e-14 (rank : 455)
Query Neighborhood Hits	2923	Target Neighborhood Hits	308	Shared Neighborhood Hits	274
SwissProt Accessions	Q60625	Gene names	Icam5, Tlcn
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

GUC2F_HUMAN
NC score	0.417399 (rank : 923)	θ value	θ > 10 (rank : 3014)
Query Neighborhood Hits	2923	Target Neighborhood Hits	740	Shared Neighborhood Hits	648
SwissProt Accessions	P51841, Q9UJF1	Gene names	GUCY2F, GUC2F, RETGC2
Domain Architecture
Description	Retinal guanylyl cyclase 2 precursor (EC 4.6.1.2) (Guanylate cyclase 2F, retinal) (RETGC-2) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2) (Guanylate cyclase F) (GC-F).

JAM2_HUMAN
NC score	0.416531 (rank : 924)	θ value	1.63604e-09 (rank : 680)
Query Neighborhood Hits	2923	Target Neighborhood Hits	304	Shared Neighborhood Hits	296
SwissProt Accessions	P57087, Q6UXG6, Q6YNC1	Gene names	JAM2, C21orf43, VEJAM
Domain Architecture
Description	Junctional adhesion molecule B precursor (JAM-B) (Junctional adhesion molecule 2) (Vascular endothelial junction-associated molecule) (VE- JAM) (CD322 antigen).

PGBM_HUMAN
NC score	0.416093 (rank : 925)	θ value	6.00439e-129 (rank : 4)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1113	Shared Neighborhood Hits	526
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

TMIGD_MOUSE
NC score	0.415810 (rank : 926)	θ value	3.41135e-07 (rank : 846)
Query Neighborhood Hits	2923	Target Neighborhood Hits	234	Shared Neighborhood Hits	233
SwissProt Accessions	Q9D7L8, Q8R202	Gene names	Tmigd
Domain Architecture	No domain graphic available
Description	Transmembrane and immunoglobulin domain-containing protein precursor.

CEAM1_MOUSE
NC score	0.415362 (rank : 927)	θ value	1.13037e-18 (rank : 301)
Query Neighborhood Hits	2923	Target Neighborhood Hits	326	Shared Neighborhood Hits	296
SwissProt Accessions	P31809	Gene names	Ceacam1, Bgp, Bgp1, Bgpd
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 1 precursor (Biliary glycoprotein 1) (BGP-1) (Murine hepatitis virus receptor) (MHV-R) (Biliary glycoprotein D).

FSTL5_HUMAN
NC score	0.415169 (rank : 928)	θ value	7.84624e-12 (rank : 559)
Query Neighborhood Hits	2923	Target Neighborhood Hits	347	Shared Neighborhood Hits	269
SwissProt Accessions	Q8N475, Q9NSW7, Q9ULF7	Gene names	FSTL5, KIAA1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5).

FSTL4_MOUSE
NC score	0.415019 (rank : 929)	θ value	2.98157e-11 (rank : 578)
Query Neighborhood Hits	2923	Target Neighborhood Hits	333	Shared Neighborhood Hits	266
SwissProt Accessions	Q5STE3, Q5DU03	Gene names	Fstl4, Kiaa1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4) (m- D/Bsp120I 1-1).

JAM3_MOUSE
NC score	0.414777 (rank : 930)	θ value	2.13673e-09 (rank : 695)
Query Neighborhood Hits	2923	Target Neighborhood Hits	286	Shared Neighborhood Hits	266
SwissProt Accessions	Q9D8B7, Q8BT59, Q9D1M9, Q9EPK4	Gene names	Jam3
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule C precursor (JAM-C) (Junctional adhesion molecule 3) (JAM-3) (JAM-2).

IGS4B_MOUSE
NC score	0.414185 (rank : 931)	θ value	1.99529e-15 (rank : 397)
Query Neighborhood Hits	2923	Target Neighborhood Hits	328	Shared Neighborhood Hits	305
SwissProt Accessions	Q99N28, Q8BSQ8, Q8K1H8	Gene names	Igsf4b, Necl1, Syncam3, Tsll1
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 4B precursor (Nectin-like protein 1) (Necl-1) (TSLC1-like protein 1) (Synaptic cell adhesion molecule 3).

FNDC3_MOUSE
NC score	0.414069 (rank : 932)	θ value	2.50074e-42 (rank : 44)
Query Neighborhood Hits	2923	Target Neighborhood Hits	207	Shared Neighborhood Hits	183
SwissProt Accessions	Q8BX90, Q2VEY7, Q6ZQ15, Q811D3, Q8BTM3	Gene names	Fndc3a, D14Ertd453e, Fndc3, Kiaa0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

PTPRS_HUMAN
NC score	0.413689 (rank : 933)	θ value	2.86786e-30 (rank : 134)
Query Neighborhood Hits	2923	Target Neighborhood Hits	472	Shared Neighborhood Hits	398
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

MUC18_MOUSE
NC score	0.412930 (rank : 934)	θ value	1.63604e-09 (rank : 682)
Query Neighborhood Hits	2923	Target Neighborhood Hits	292	Shared Neighborhood Hits	262
SwissProt Accessions	Q8R2Y2, Q9EPF1, Q9ESS7, Q9JHQ2, Q9JHQ3	Gene names	Mcam, Muc18
Domain Architecture	No domain graphic available
Description	Cell surface glycoprotein MUC18 precursor (Melanoma-associated antigen MUC18) (Melanoma cell adhesion molecule) (Gicerin).

NPTN_MOUSE
NC score	0.412025 (rank : 935)	θ value	1.86753e-13 (rank : 484)
Query Neighborhood Hits	2923	Target Neighborhood Hits	216	Shared Neighborhood Hits	212
SwissProt Accessions	P97300, Q3U519, Q8C637, Q8C6H8	Gene names	Nptn, Sdfr1, Sdr1
Domain Architecture	No domain graphic available
Description	Neuroplastin precursor (Stromal cell-derived receptor 1) (SDR-1).

JAM3_HUMAN
NC score	0.410858 (rank : 936)	θ value	3.64472e-09 (rank : 715)
Query Neighborhood Hits	2923	Target Neighborhood Hits	271	Shared Neighborhood Hits	262
SwissProt Accessions	Q9BX67, Q8WWL8, Q96FL1	Gene names	JAM3
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule C precursor (JAM-C) (Junctional adhesion molecule 3) (JAM-3) (JAM-2).

FNDC3_HUMAN
NC score	0.410101 (rank : 937)	θ value	2.76489e-41 (rank : 53)
Query Neighborhood Hits	2923	Target Neighborhood Hits	196	Shared Neighborhood Hits	183
SwissProt Accessions	Q9Y2H6, Q5JVF9, Q6EVH3, Q6N020, Q6P9D5, Q9H1W1	Gene names	FNDC3A, FNDC3, KIAA0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

FSTL5_MOUSE
NC score	0.409943 (rank : 938)	θ value	1.133e-10 (rank : 621)
Query Neighborhood Hits	2923	Target Neighborhood Hits	355	Shared Neighborhood Hits	267
SwissProt Accessions	Q8BFR2, Q80TG3, Q8C4T3	Gene names	Fstl5, Kiaa1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5) (m- D/Bsp120I 1-2).

RAGE_MOUSE
NC score	0.408865 (rank : 939)	θ value	1.53129e-07 (rank : 822)
Query Neighborhood Hits	2923	Target Neighborhood Hits	295	Shared Neighborhood Hits	243
SwissProt Accessions	Q62151	Gene names	Ager, Rage
Domain Architecture
Description	Advanced glycosylation end product-specific receptor precursor (Receptor for advanced glycosylation end products).

TEX14_MOUSE
NC score	0.408701 (rank : 940)	θ value	θ > 10 (rank : 3112)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1333	Shared Neighborhood Hits	828
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

NPTN_HUMAN
NC score	0.408578 (rank : 941)	θ value	1.74796e-11 (rank : 573)
Query Neighborhood Hits	2923	Target Neighborhood Hits	212	Shared Neighborhood Hits	208
SwissProt Accessions	Q9Y639, Q59EJ9, Q6NVX7, Q9Y640	Gene names	NPTN, SDFR1, SDR1
Domain Architecture	No domain graphic available
Description	Neuroplastin precursor (Stromal cell-derived receptor 1) (SDR-1).

FCRL5_HUMAN
NC score	0.406437 (rank : 942)	θ value	2.12685e-25 (rank : 171)
Query Neighborhood Hits	2923	Target Neighborhood Hits	267	Shared Neighborhood Hits	250
SwissProt Accessions	Q96RD9, Q495Q2, Q495Q4, Q5VYK9, Q6UY46	Gene names	FCRL5, FCRH5, IRTA2
Domain Architecture	No domain graphic available
Description	Fc receptor-like protein 5 precursor (Immunoglobulin receptor translocation-associated gene 2 protein) (BXMAS1) (CD307 antigen).

JAM2_MOUSE
NC score	0.405521 (rank : 943)	θ value	8.11959e-09 (rank : 736)
Query Neighborhood Hits	2923	Target Neighborhood Hits	292	Shared Neighborhood Hits	276
SwissProt Accessions	Q9JI59, Q8C5K9, Q8CE95	Gene names	Jam2, Vejam
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule B precursor (JAM-B) (Junctional adhesion molecule 2) (Vascular endothelial junction-associated molecule) (VE- JAM) (CD322 antigen).

IGS4B_HUMAN
NC score	0.405291 (rank : 944)	θ value	1.2105e-12 (rank : 507)
Query Neighborhood Hits	2923	Target Neighborhood Hits	305	Shared Neighborhood Hits	288
SwissProt Accessions	Q8N126, Q9NVJ5, Q9UJP1	Gene names	IGSF4B, NECL1, SYNCAM3, TSLL1
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 4B precursor (Nectin-like protein 1) (TSLC1-like protein 1) (Synaptic cell adhesion molecule 3) (Brain immunoglobulin receptor).

ICAM5_HUMAN
NC score	0.405152 (rank : 945)	θ value	4.44505e-15 (rank : 409)
Query Neighborhood Hits	2923	Target Neighborhood Hits	276	Shared Neighborhood Hits	256
SwissProt Accessions	Q9UMF0, Q9Y6F3	Gene names	ICAM5, TLCN, TLN
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

PGBM_MOUSE
NC score	0.401515 (rank : 946)	θ value	9.39325e-82 (rank : 8)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1073	Shared Neighborhood Hits	512
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

CEA20_HUMAN
NC score	0.398917 (rank : 947)	θ value	1.74796e-11 (rank : 570)
Query Neighborhood Hits	2923	Target Neighborhood Hits	251	Shared Neighborhood Hits	232
SwissProt Accessions	Q6UY09	Gene names	CEACAM20
Domain Architecture	No domain graphic available
Description	Carcinoembryonic antigen-related cell adhesion molecule 20 precursor.

VRK1_MOUSE
NC score	0.389227 (rank : 948)	θ value	0.0431538 (rank : 1299)
Query Neighborhood Hits	2923	Target Neighborhood Hits	583	Shared Neighborhood Hits	566
SwissProt Accessions	Q80X41, O88635, O88636, Q8C2P7, Q91YH9	Gene names	Vrk1
Domain Architecture
Description	Serine/threonine-protein kinase VRK1 (EC 2.7.11.1) (Vaccinia-related kinase 1) (Serine/threonine-protein kinase 51PK).

FCRL2_HUMAN
NC score	0.387469 (rank : 949)	θ value	2.43908e-13 (rank : 487)
Query Neighborhood Hits	2923	Target Neighborhood Hits	251	Shared Neighborhood Hits	231
SwissProt Accessions	Q96LA5, Q6NTA1, Q9BZI4, Q9BZI5, Q9BZI6	Gene names	FCRL2, FCRH2, IFGP4, IRTA4, SPAP1
Domain Architecture	No domain graphic available
Description	Fc receptor-like protein 2 precursor (SH2 domain-containing phosphatase anchor protein 1) (Fc receptor homolog 2) (FcRH2) (Immunoglobulin receptor translocation-associated 4 protein).

AMHR2_HUMAN
NC score	0.386842 (rank : 950)	θ value	θ > 10 (rank : 2939)
Query Neighborhood Hits	2923	Target Neighborhood Hits	715	Shared Neighborhood Hits	621
SwissProt Accessions	Q16671, Q13762	Gene names	AMHR2, AMHR
Domain Architecture
Description	Anti-Muellerian hormone type-2 receptor precursor (EC 2.7.11.30) (Anti-Muellerian hormone type II receptor) (AMH type II receptor) (MIS type II receptor) (MISRII) (MRII).

SIG11_HUMAN
NC score	0.385108 (rank : 951)	θ value	7.34386e-10 (rank : 662)
Query Neighborhood Hits	2923	Target Neighborhood Hits	273	Shared Neighborhood Hits	255
SwissProt Accessions	Q96RL6	Gene names	SIGLEC11
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 11 precursor (Siglec-11) (Sialic acid-binding lectin 11).

CEAM1_HUMAN
NC score	0.384959 (rank : 952)	θ value	2.60593e-15 (rank : 402)
Query Neighborhood Hits	2923	Target Neighborhood Hits	348	Shared Neighborhood Hits	316
SwissProt Accessions	P13688, O60430, Q13858, Q15600, Q9UQV9	Gene names	CEACAM1, BGP, BGP1
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 1 precursor (Biliary glycoprotein 1) (BGP-1) (CD66 antigen) (CD66a antigen).

NRBP_HUMAN
NC score	0.384249 (rank : 953)	θ value	0.00102713 (rank : 1086)
Query Neighborhood Hits	2923	Target Neighborhood Hits	448	Shared Neighborhood Hits	406
SwissProt Accessions	Q9UHY1, Q53FZ5, Q96SU3	Gene names	NRBP1, BCON3, NRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor-binding protein.

VRK2_HUMAN
NC score	0.383526 (rank : 954)	θ value	0.279714 (rank : 1527)
Query Neighborhood Hits	2923	Target Neighborhood Hits	582	Shared Neighborhood Hits	555
SwissProt Accessions	Q86Y07, Q49AK9, Q53EU9, Q86Y08, Q86Y09, Q86Y10, Q86Y11, Q86Y12, Q8IXI5, Q99987	Gene names	VRK2
Domain Architecture
Description	Serine/threonine-protein kinase VRK2 (EC 2.7.11.1) (Vaccinia-related kinase 2).

VRK1_HUMAN
NC score	0.383370 (rank : 955)	θ value	0.21417 (rank : 1482)
Query Neighborhood Hits	2923	Target Neighborhood Hits	584	Shared Neighborhood Hits	566
SwissProt Accessions	Q99986	Gene names	VRK1
Domain Architecture
Description	Serine/threonine-protein kinase VRK1 (EC 2.7.11.1) (Vaccinia-related kinase 1).

VRK2_MOUSE
NC score	0.383122 (rank : 956)	θ value	3.0926 (rank : 2240)
Query Neighborhood Hits	2923	Target Neighborhood Hits	586	Shared Neighborhood Hits	567
SwissProt Accessions	Q8BN21, Q5F1Z5, Q5SP88, Q8BPU8, Q8CJ46, Q91WS1, Q9CZF9	Gene names	Vrk2
Domain Architecture
Description	Serine/threonine-protein kinase VRK2 (EC 2.7.11.1) (Vaccinia-related kinase 2).

VSIG2_HUMAN
NC score	0.383040 (rank : 957)	θ value	8.97725e-08 (rank : 799)
Query Neighborhood Hits	2923	Target Neighborhood Hits	321	Shared Neighborhood Hits	282
SwissProt Accessions	Q96IQ7, O95791, Q9NX42	Gene names	VSIG2, CTH, CTXL
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 2 precursor (CT- like protein) (Cortical thymocyte-like protein).

NRBP_MOUSE
NC score	0.382601 (rank : 958)	θ value	0.00102713 (rank : 1087)
Query Neighborhood Hits	2923	Target Neighborhood Hits	442	Shared Neighborhood Hits	405
SwissProt Accessions	Q99J45, Q8BL77	Gene names	Nrbp1, Madm, Nrbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor-binding protein (MLF1 adapter molecule) (HLS7- interacting protein kinase).

LRIG1_HUMAN
NC score	0.381708 (rank : 959)	θ value	5.97985e-28 (rank : 147)
Query Neighborhood Hits	2923	Target Neighborhood Hits	654	Shared Neighborhood Hits	385
SwissProt Accessions	Q96JA1, Q6IQ51, Q96CF9, Q9BYB8, Q9UFI4	Gene names	LRIG1, LIG1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

SIG10_HUMAN
NC score	0.379473 (rank : 960)	θ value	1.25267e-09 (rank : 673)
Query Neighborhood Hits	2923	Target Neighborhood Hits	363	Shared Neighborhood Hits	289
SwissProt Accessions	Q96LC7, Q6UXI8, Q96G54, Q96LC8	Gene names	SIGLEC10, SLG2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 10 precursor (Siglec-10) (Siglec- like protein 2).

GUC2C_HUMAN
NC score	0.377970 (rank : 961)	θ value	θ > 10 (rank : 3011)
Query Neighborhood Hits	2923	Target Neighborhood Hits	624	Shared Neighborhood Hits	547
SwissProt Accessions	P25092	Gene names	GUCY2C, GUC2C, STAR
Domain Architecture
Description	Heat-stable enterotoxin receptor precursor (GC-C) (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) (hSTAR).

BASI_HUMAN
NC score	0.377039 (rank : 962)	θ value	1.80886e-08 (rank : 753)
Query Neighborhood Hits	2923	Target Neighborhood Hits	211	Shared Neighborhood Hits	205
SwissProt Accessions	P35613, Q7Z796, Q8IZL7	Gene names	BSG
Domain Architecture
Description	Basigin precursor (Leukocyte activation antigen M6) (Collagenase stimulatory factor) (Extracellular matrix metalloproteinase inducer) (EMMPRIN) (5F7) (Tumor cell-derived collagenase stimulatory factor) (TCSF) (OK blood group antigen) (CD147 antigen).

GUC2D_HUMAN
NC score	0.374296 (rank : 963)	θ value	θ > 10 (rank : 3012)
Query Neighborhood Hits	2923	Target Neighborhood Hits	715	Shared Neighborhood Hits	624
SwissProt Accessions	Q02846, Q6LEA7	Gene names	GUCY2D, CORD6, GUC1A4, GUC2D, RETGC, RETGC1
Domain Architecture
Description	Retinal guanylyl cyclase 1 precursor (EC 4.6.1.2) (Guanylate cyclase 2D, retinal) (RETGC-1) (Rod outer segment membrane guanylate cyclase) (ROS-GC).

LRIG2_HUMAN
NC score	0.372883 (rank : 964)	θ value	2.51237e-26 (rank : 163)
Query Neighborhood Hits	2923	Target Neighborhood Hits	595	Shared Neighborhood Hits	358
SwissProt Accessions	O94898, Q9NSN2	Gene names	LRIG2, KIAA0806, LIG2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor (LIG-2).

TEX14_HUMAN
NC score	0.372602 (rank : 965)	θ value	1.81305 (rank : 1994)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1103	Shared Neighborhood Hits	690
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

VSIG2_MOUSE
NC score	0.371145 (rank : 966)	θ value	2.88788e-06 (rank : 903)
Query Neighborhood Hits	2923	Target Neighborhood Hits	316	Shared Neighborhood Hits	264
SwissProt Accessions	Q9Z109, Q9CVA4, Q9D0T4	Gene names	Vsig2, Ctm, Ctxl
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 2 precursor (CT- like protein) (Cortical thymocyte-like protein).

LRIG1_MOUSE
NC score	0.370598 (rank : 967)	θ value	1.02001e-27 (rank : 152)
Query Neighborhood Hits	2923	Target Neighborhood Hits	627	Shared Neighborhood Hits	371
SwissProt Accessions	P70193	Gene names	Lrig1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

LRIG2_MOUSE
NC score	0.370585 (rank : 968)	θ value	1.24688e-25 (rank : 166)
Query Neighborhood Hits	2923	Target Neighborhood Hits	586	Shared Neighborhood Hits	350
SwissProt Accessions	Q52KR2, Q69ZY8	Gene names	Lrig2, Kiaa0806
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor.

BASI_MOUSE
NC score	0.367418 (rank : 969)	θ value	6.87365e-08 (rank : 781)
Query Neighborhood Hits	2923	Target Neighborhood Hits	238	Shared Neighborhood Hits	225
SwissProt Accessions	P18572, Q6LDB0, Q7TSC0	Gene names	Bsg
Domain Architecture
Description	Basigin precursor (Basic immunoglobulin superfamily) (Membrane glycoprotein gp42) (HT7 antigen) (CD147 antigen).

LRIG3_MOUSE
NC score	0.360288 (rank : 970)	θ value	2.12685e-25 (rank : 172)
Query Neighborhood Hits	2923	Target Neighborhood Hits	611	Shared Neighborhood Hits	361
SwissProt Accessions	Q6P1C6, Q6ZPE6, Q8BRF0, Q8BS51, Q8C5E4	Gene names	Lrig3, Kiaa3016
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor.

GUC2E_MOUSE
NC score	0.358840 (rank : 971)	θ value	θ > 10 (rank : 3013)
Query Neighborhood Hits	2923	Target Neighborhood Hits	692	Shared Neighborhood Hits	600
SwissProt Accessions	P52785	Gene names	Gucy2e, Guc2e
Domain Architecture
Description	Guanylyl cyclase GC-E precursor (EC 4.6.1.2) (Guanylate cyclase 2E).

VSIG4_HUMAN
NC score	0.355892 (rank : 972)	θ value	1.99992e-07 (rank : 827)
Query Neighborhood Hits	2923	Target Neighborhood Hits	236	Shared Neighborhood Hits	230
SwissProt Accessions	Q9Y279, Q6UXI4	Gene names	VSIG4, Z39IG
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 4 precursor (Protein Z39Ig).

LRIG3_HUMAN
NC score	0.355743 (rank : 973)	θ value	4.73814e-25 (rank : 174)
Query Neighborhood Hits	2923	Target Neighborhood Hits	601	Shared Neighborhood Hits	357
SwissProt Accessions	Q6UXM1, Q6UXL7, Q8NC72	Gene names	LRIG3, LIG3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor (LIG-3).

KAZD1_MOUSE
NC score	0.351633 (rank : 974)	θ value	1.09739e-05 (rank : 934)
Query Neighborhood Hits	2923	Target Neighborhood Hits	281	Shared Neighborhood Hits	209
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).

CI094_HUMAN
NC score	0.350354 (rank : 975)	θ value	7.34386e-10 (rank : 658)
Query Neighborhood Hits	2923	Target Neighborhood Hits	310	Shared Neighborhood Hits	241
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

GUC2G_MOUSE
NC score	0.350330 (rank : 976)	θ value	θ > 10 (rank : 3015)
Query Neighborhood Hits	2923	Target Neighborhood Hits	644	Shared Neighborhood Hits	540
SwissProt Accessions	Q6TL19, Q8BWU7	Gene names	Gucy2g
Domain Architecture	No domain graphic available
Description	Guanylate cyclase 2G precursor (EC 4.6.1.2) (Guanylyl cyclase receptor G) (mGC-G).

ANPRB_HUMAN
NC score	0.350152 (rank : 977)	θ value	θ > 10 (rank : 2944)
Query Neighborhood Hits	2923	Target Neighborhood Hits	646	Shared Neighborhood Hits	538
SwissProt Accessions	P20594, O60871, Q9UQ50	Gene names	NPR2, ANPRB
Domain Architecture
Description	Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor).

MFA3L_HUMAN
NC score	0.347392 (rank : 978)	θ value	4.92598e-06 (rank : 913)
Query Neighborhood Hits	2923	Target Neighborhood Hits	230	Shared Neighborhood Hits	220
SwissProt Accessions	O75121, Q6TNA8, Q9BVE1, Q9BXK0	Gene names	MFAP3L, KIAA0626
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 3-like precursor (Protein kinase NYD-SP9).

CEAM6_HUMAN
NC score	0.346722 (rank : 979)	θ value	1.09485e-13 (rank : 472)
Query Neighborhood Hits	2923	Target Neighborhood Hits	308	Shared Neighborhood Hits	291
SwissProt Accessions	P40199, Q14920	Gene names	CEACAM6, NCA
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 6 precursor (Normal cross-reacting antigen) (Nonspecific crossreacting antigen) (CD66c antigen).

ILK1_HUMAN
NC score	0.345598 (rank : 980)	θ value	2.36792 (rank : 2061)
Query Neighborhood Hits	2923	Target Neighborhood Hits	857	Shared Neighborhood Hits	567
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

CD166_MOUSE
NC score	0.344537 (rank : 981)	θ value	1.09739e-05 (rank : 930)
Query Neighborhood Hits	2923	Target Neighborhood Hits	252	Shared Neighborhood Hits	234
SwissProt Accessions	Q61490, O70136, Q8CDA5, Q8R2T0	Gene names	Alcam
Domain Architecture
Description	CD166 antigen precursor (Activated leukocyte-cell adhesion molecule) (ALCAM) (DM-GRASP protein).

ILK_MOUSE
NC score	0.343798 (rank : 982)	θ value	2.36792 (rank : 2063)
Query Neighborhood Hits	2923	Target Neighborhood Hits	858	Shared Neighborhood Hits	568
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

BUB1_HUMAN
NC score	0.342806 (rank : 983)	θ value	θ > 10 (rank : 2956)
Query Neighborhood Hits	2923	Target Neighborhood Hits	543	Shared Neighborhood Hits	469
SwissProt Accessions	O43683, O43430, O43643, O60626	Gene names	BUB1, BUB1L
Domain Architecture
Description	Mitotic checkpoint serine/threonine-protein kinase BUB1 (EC 2.7.11.1) (hBUB1) (BUB1A).

NRG2_HUMAN
NC score	0.342490 (rank : 984)	θ value	3.41135e-07 (rank : 844)
Query Neighborhood Hits	2923	Target Neighborhood Hits	419	Shared Neighborhood Hits	287
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

GPA33_MOUSE
NC score	0.339946 (rank : 985)	θ value	1.43324e-05 (rank : 940)
Query Neighborhood Hits	2923	Target Neighborhood Hits	294	Shared Neighborhood Hits	252
SwissProt Accessions	Q9JKA5, Q922D5	Gene names	Gpa33
Domain Architecture
Description	Cell surface A33 antigen precursor (Glycoprotein A33) (mA33).

ILK2_HUMAN
NC score	0.335641 (rank : 986)	θ value	2.36792 (rank : 2062)
Query Neighborhood Hits	2923	Target Neighborhood Hits	848	Shared Neighborhood Hits	562
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

NRG2_MOUSE
NC score	0.335392 (rank : 987)	θ value	2.61198e-07 (rank : 836)
Query Neighborhood Hits	2923	Target Neighborhood Hits	392	Shared Neighborhood Hits	269
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

CD166_HUMAN
NC score	0.331352 (rank : 988)	θ value	3.41135e-07 (rank : 840)
Query Neighborhood Hits	2923	Target Neighborhood Hits	247	Shared Neighborhood Hits	229
SwissProt Accessions	Q13740, O60892	Gene names	ALCAM, MEMD
Domain Architecture
Description	CD166 antigen precursor (Activated leukocyte-cell adhesion molecule) (ALCAM).

FINC_MOUSE
NC score	0.329248 (rank : 989)	θ value	7.52953e-39 (rank : 60)
Query Neighborhood Hits	2923	Target Neighborhood Hits	309	Shared Neighborhood Hits	215
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

ANPRB_MOUSE
NC score	0.328128 (rank : 990)	θ value	θ > 10 (rank : 2945)
Query Neighborhood Hits	2923	Target Neighborhood Hits	607	Shared Neighborhood Hits	513
SwissProt Accessions	Q6VVW5, Q6VVW3, Q6VVW4, Q8CGA9	Gene names	Npr2
Domain Architecture	No domain graphic available
Description	Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor).

ANPRA_HUMAN
NC score	0.327405 (rank : 991)	θ value	θ > 10 (rank : 2942)
Query Neighborhood Hits	2923	Target Neighborhood Hits	612	Shared Neighborhood Hits	507
SwissProt Accessions	P16066, Q6P4Q3	Gene names	NPR1, ANPRA
Domain Architecture
Description	Atrial natriuretic peptide receptor A precursor (ANP-A) (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor).

ANPRA_MOUSE
NC score	0.326646 (rank : 992)	θ value	θ > 10 (rank : 2943)
Query Neighborhood Hits	2923	Target Neighborhood Hits	600	Shared Neighborhood Hits	503
SwissProt Accessions	P18293	Gene names	Npr1, Npra
Domain Architecture
Description	Atrial natriuretic peptide receptor A precursor (ANP-A) (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor).

GPA33_HUMAN
NC score	0.324936 (rank : 993)	θ value	4.1701e-05 (rank : 974)
Query Neighborhood Hits	2923	Target Neighborhood Hits	273	Shared Neighborhood Hits	238
SwissProt Accessions	Q99795	Gene names	GPA33
Domain Architecture
Description	Cell surface A33 antigen precursor (Glycoprotein A33).

FINC_HUMAN
NC score	0.323993 (rank : 994)	θ value	3.27365e-34 (rank : 94)
Query Neighborhood Hits	2923	Target Neighborhood Hits	302	Shared Neighborhood Hits	217
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

KAZD1_HUMAN
NC score	0.318131 (rank : 995)	θ value	4.1701e-05 (rank : 976)
Query Neighborhood Hits	2923	Target Neighborhood Hits	248	Shared Neighborhood Hits	174
SwissProt Accessions	Q96I82, Q6ZMB1, Q9BQ73	Gene names	KAZALD1
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor.

SIGL5_MOUSE
NC score	0.317628 (rank : 996)	θ value	1.43324e-05 (rank : 941)
Query Neighborhood Hits	2923	Target Neighborhood Hits	271	Shared Neighborhood Hits	258
SwissProt Accessions	Q920G3	Gene names	Siglec5, Siglecf
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 5 precursor (Siglec-5) (Sialic acid-binding Ig-like lectin-F) (mSiglec-F).

CEAM8_HUMAN
NC score	0.312611 (rank : 997)	θ value	9.59137e-10 (rank : 664)
Query Neighborhood Hits	2923	Target Neighborhood Hits	264	Shared Neighborhood Hits	248
SwissProt Accessions	P31997, O60399, Q16574	Gene names	CEACAM8, CGM6
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 8 precursor (Carcinoembryonic antigen CGM6) (Nonspecific cross-reacting antigen NCA-95) (CD67 antigen) (CD66b antigen).

PI3R4_MOUSE
NC score	0.311154 (rank : 998)	θ value	0.21417 (rank : 1474)
Query Neighborhood Hits	2923	Target Neighborhood Hits	535	Shared Neighborhood Hits	364
SwissProt Accessions	Q8VD65, Q56A65, Q8C948, Q8C9D7, Q9CVC5	Gene names	Pik3r4
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 4 (EC 2.7.11.1) (PI3- kinase regulatory subunit 4).

IBP7_HUMAN
NC score	0.302358 (rank : 999)	θ value	0.00102713 (rank : 1080)
Query Neighborhood Hits	2923	Target Neighborhood Hits	220	Shared Neighborhood Hits	168
SwissProt Accessions	Q16270, Q07822	Gene names	IGFBP7, MAC25, PSF
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein) (Prostacyclin-stimulating factor) (PGI2-stimulating factor) (IGFBP-rP1).

PSG8_HUMAN
NC score	0.301544 (rank : 1000)	θ value	6.64225e-11 (rank : 608)
Query Neighborhood Hits	2923	Target Neighborhood Hits	239	Shared Neighborhood Hits	231
SwissProt Accessions	Q9UQ74, O60410	Gene names	PSG8
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 8 precursor (PSBG-8).

ESAM_HUMAN
NC score	0.301398 (rank : 1001)	θ value	1.09739e-05 (rank : 932)
Query Neighborhood Hits	2923	Target Neighborhood Hits	251	Shared Neighborhood Hits	218
SwissProt Accessions	Q96AP7, Q96T50	Gene names	ESAM
Domain Architecture	No domain graphic available
Description	Endothelial cell-selective adhesion molecule precursor.

PSG3_HUMAN
NC score	0.299433 (rank : 1002)	θ value	5.26297e-08 (rank : 778)
Query Neighborhood Hits	2923	Target Neighborhood Hits	242	Shared Neighborhood Hits	231
SwissProt Accessions	Q16557, Q08265, Q9BRW2, Q9UPL4, Q9UQ77	Gene names	PSG3
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 3 precursor (PSBG-3) (Carcinoembryonic antigen SG5).

NTKL_MOUSE
NC score	0.297749 (rank : 1003)	θ value	0.00102713 (rank : 1088)
Query Neighborhood Hits	2923	Target Neighborhood Hits	326	Shared Neighborhood Hits	293
SwissProt Accessions	Q9EQC5, Q3TST7, Q3UKU0, Q8K222	Gene names	Scyl1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like protein (SCY1-like protein 1) (105 kDa kinase- like protein) (Mitosis-associated kinase-like protein NTKL).

MFA3L_MOUSE
NC score	0.297242 (rank : 1004)	θ value	2.44474e-05 (rank : 956)
Query Neighborhood Hits	2923	Target Neighborhood Hits	214	Shared Neighborhood Hits	203
SwissProt Accessions	Q9D3X9, Q80TV6, Q8BJA9	Gene names	Mfap3l, Kiaa0626
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 3-like precursor.

PSG4_HUMAN
NC score	0.295919 (rank : 1005)	θ value	8.11959e-09 (rank : 737)
Query Neighborhood Hits	2923	Target Neighborhood Hits	243	Shared Neighborhood Hits	233
SwissProt Accessions	Q00888, Q13047, Q13048, Q15234, Q15240, Q9UQ76	Gene names	PSG4, CGM4, PSG9
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 4 precursor (PSBG-4) (PSBG-9).

PI3R4_HUMAN
NC score	0.295788 (rank : 1006)	θ value	1.38821 (rank : 1873)
Query Neighborhood Hits	2923	Target Neighborhood Hits	534	Shared Neighborhood Hits	350
SwissProt Accessions	Q99570	Gene names	PIK3R4
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 4 (EC 2.7.11.1) (PI3- kinase regulatory subunit 4) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein).

STK31_HUMAN
NC score	0.294817 (rank : 1007)	θ value	θ > 10 (rank : 3105)
Query Neighborhood Hits	2923	Target Neighborhood Hits	570	Shared Neighborhood Hits	476
SwissProt Accessions	Q9BXU1, Q9BXH8	Gene names	STK31
Domain Architecture
Description	Serine/threonine-protein kinase 31 (EC 2.7.11.1) (Serine/threonine- protein kinase NYD-SPK).

IBP7_MOUSE
NC score	0.291945 (rank : 1008)	θ value	0.00228821 (rank : 1115)
Query Neighborhood Hits	2923	Target Neighborhood Hits	230	Shared Neighborhood Hits	168
SwissProt Accessions	Q61581, O88812, Q9EQW0	Gene names	Igfbp7, Mac25
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).

PSG7_HUMAN
NC score	0.291473 (rank : 1009)	θ value	7.34386e-10 (rank : 661)
Query Neighborhood Hits	2923	Target Neighborhood Hits	239	Shared Neighborhood Hits	229
SwissProt Accessions	Q13046, Q15232	Gene names	PSG7
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 7 precursor (PSBG-7).

PSG11_HUMAN
NC score	0.288331 (rank : 1010)	θ value	3.08544e-08 (rank : 766)
Query Neighborhood Hits	2923	Target Neighborhood Hits	223	Shared Neighborhood Hits	217
SwissProt Accessions	Q9UQ72, Q13179, Q15242, Q9UNE4	Gene names	PSG11, PSG13
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 11 precursor (PSBG-11) (PSBG- 13).

PSG2_HUMAN
NC score	0.286632 (rank : 1011)	θ value	1.25267e-09 (rank : 672)
Query Neighborhood Hits	2923	Target Neighborhood Hits	229	Shared Neighborhood Hits	224
SwissProt Accessions	P11465, Q8TCD9, Q9UEA4, Q9UQ78	Gene names	PSG2
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 2 precursor (PSBG-2) (Pregnancy-specific beta-1 glycoprotein E) (PS-beta-E).

PSG1_HUMAN
NC score	0.285345 (rank : 1012)	θ value	3.64472e-09 (rank : 716)
Query Neighborhood Hits	2923	Target Neighborhood Hits	232	Shared Neighborhood Hits	223
SwissProt Accessions	P11464, O75236, P11462, P11463, Q15231, Q15241, Q15243, Q16660, Q9P1W5, Q9UQ79	Gene names	PSG1, B1G1, PSGGA
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 1 precursor (PSBG-1) (Pregnancy-specific beta-1 glycoprotein C/D) (PS-beta-C/D) (Fetal liver non-specific cross-reactive antigen 1/2) (FL-NCA-1/2) (PSG95) (CD66f antigen).

ATL3_HUMAN
NC score	0.283502 (rank : 1013)	θ value	9.26847e-13 (rank : 502)
Query Neighborhood Hits	2923	Target Neighborhood Hits	414	Shared Neighborhood Hits	290
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

PSG6_HUMAN
NC score	0.281174 (rank : 1014)	θ value	1.38499e-08 (rank : 750)
Query Neighborhood Hits	2923	Target Neighborhood Hits	231	Shared Neighborhood Hits	220
SwissProt Accessions	Q00889	Gene names	PSG6, CGM3, PSGGB
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 6 precursor (PSBG-6).

K2002_HUMAN
NC score	0.279858 (rank : 1015)	θ value	0.47712 (rank : 1609)
Query Neighborhood Hits	2923	Target Neighborhood Hits	274	Shared Neighborhood Hits	261
SwissProt Accessions	Q9H792, Q6ZS78, Q8NCM3	Gene names	KIAA2002
Domain Architecture	No domain graphic available
Description	Uncharacterized tyrosine-protein kinase KIAA2002 (EC 2.7.10.2).

PSG10_HUMAN
NC score	0.278645 (rank : 1016)	θ value	1.38499e-08 (rank : 749)
Query Neighborhood Hits	2923	Target Neighborhood Hits	227	Shared Neighborhood Hits	218
SwissProt Accessions	Q15235, O75244, Q15224	Gene names	PSG10, PSG12
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 10 precursor (PSBG-10) (PSBG- 12).

CXAR_HUMAN
NC score	0.278133 (rank : 1017)	θ value	1.80886e-08 (rank : 755)
Query Neighborhood Hits	2923	Target Neighborhood Hits	245	Shared Neighborhood Hits	218
SwissProt Accessions	P78310, O00694, Q8WWT6, Q8WWT7, Q8WWT8, Q9UKV4	Gene names	CXADR, CAR
Domain Architecture
Description	Coxsackievirus and adenovirus receptor precursor (Coxsackievirus B- adenovirus receptor) (hCAR) (CVB3-binding protein) (HCVADR).

CD276_HUMAN
NC score	0.274297 (rank : 1018)	θ value	7.84624e-12 (rank : 557)
Query Neighborhood Hits	2923	Target Neighborhood Hits	261	Shared Neighborhood Hits	222
SwissProt Accessions	Q5ZPR3, Q6P5Y4, Q6UXI2, Q8NBI8, Q8NC34, Q8NCB6, Q9BXR1	Gene names	CD276, B7H3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3) (4Ig-B7-H3).

PSG9_HUMAN
NC score	0.273848 (rank : 1019)	θ value	1.38499e-08 (rank : 751)
Query Neighborhood Hits	2923	Target Neighborhood Hits	221	Shared Neighborhood Hits	214
SwissProt Accessions	Q00887, Q15236, Q15237, Q8WW78, Q9UQ73	Gene names	PSG9, PSG11
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 9 precursor (PSBG-9) (Pregnancy-specific glycoprotein 9) (Pregnancy-specific beta-1 glycoprotein B) (PS-beta-B) (PS34) (Pregnancy-specific glycoprotein 7) (PSG7).

PSG5_HUMAN
NC score	0.271729 (rank : 1020)	θ value	9.29e-05 (rank : 1003)
Query Neighborhood Hits	2923	Target Neighborhood Hits	231	Shared Neighborhood Hits	223
SwissProt Accessions	Q15238, Q15239, Q96QJ1, Q9UQ75	Gene names	PSG5
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 5 precursor (PSBG-5) (Fetal liver non-specific cross-reactive antigen 3) (FL-NCA-3).

PECA1_HUMAN
NC score	0.271628 (rank : 1021)	θ value	1.74796e-11 (rank : 574)
Query Neighborhood Hits	2923	Target Neighborhood Hits	178	Shared Neighborhood Hits	170
SwissProt Accessions	P16284, Q6LDA9, Q8TBH1, Q96RF5, Q96RF6, Q9NP65, Q9NPB7, Q9NPG9, Q9NQS9, Q9NQT0, Q9NQT1, Q9NQT2	Gene names	PECAM1
Domain Architecture
Description	Platelet endothelial cell adhesion molecule precursor (PECAM-1) (EndoCAM) (GPIIA') (CD31 antigen).

ESAM_MOUSE
NC score	0.269005 (rank : 1022)	θ value	0.00020696 (rank : 1030)
Query Neighborhood Hits	2923	Target Neighborhood Hits	222	Shared Neighborhood Hits	204
SwissProt Accessions	Q925F2	Gene names	Esam, Esam1
Domain Architecture	No domain graphic available
Description	Endothelial cell-selective adhesion molecule precursor.

SIGL5_HUMAN
NC score	0.266754 (rank : 1023)	θ value	0.000786445 (rank : 1077)
Query Neighborhood Hits	2923	Target Neighborhood Hits	246	Shared Neighborhood Hits	219
SwissProt Accessions	O15389	Gene names	SIGLEC5, CD33L2, OBBP2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 5 precursor (Siglec-5) (Obesity- binding protein 2) (OB-binding protein 2) (OB-BP2) (CD33 antigen-like 2) (CD170 antigen).

CXAR_MOUSE
NC score	0.265560 (rank : 1024)	θ value	4.0297e-08 (rank : 769)
Query Neighborhood Hits	2923	Target Neighborhood Hits	250	Shared Neighborhood Hits	223
SwissProt Accessions	P97792, O09052, Q3ULD0, Q91W66, Q99KG0, Q9DBJ8	Gene names	Cxadr, Car
Domain Architecture
Description	Coxsackievirus and adenovirus receptor homolog precursor (CAR) (mCAR).

NRG1_HUMAN
NC score	0.263713 (rank : 1025)	θ value	9.92553e-07 (rank : 879)
Query Neighborhood Hits	2923	Target Neighborhood Hits	285	Shared Neighborhood Hits	199
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

SIGL8_HUMAN
NC score	0.262385 (rank : 1026)	θ value	6.43352e-06 (rank : 920)
Query Neighborhood Hits	2923	Target Neighborhood Hits	252	Shared Neighborhood Hits	234
SwissProt Accessions	Q9NYZ4, Q7Z728	Gene names	SIGLEC8, SAF2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 8 precursor (Siglec-8) (Sialoadhesin family member 2) (SAF-2) (CDw329 antigen).

RN5A_MOUSE
NC score	0.258106 (rank : 1027)	θ value	1.06291 (rank : 1809)
Query Neighborhood Hits	2923	Target Neighborhood Hits	899	Shared Neighborhood Hits	611
SwissProt Accessions	Q05921, Q9ERU7	Gene names	Rnasel, Rns4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

IL1R2_HUMAN
NC score	0.258063 (rank : 1028)	θ value	3.19293e-05 (rank : 964)
Query Neighborhood Hits	2923	Target Neighborhood Hits	153	Shared Neighborhood Hits	150
SwissProt Accessions	P27930, Q9UE68	Gene names	IL1R2, IL1RB
Domain Architecture
Description	Interleukin-1 receptor type II precursor (IL-1R-2) (IL-1R-beta) (CD121b antigen) (CDw121b).

SIG12_HUMAN
NC score	0.257065 (rank : 1029)	θ value	5.81887e-07 (rank : 861)
Query Neighborhood Hits	2923	Target Neighborhood Hits	245	Shared Neighborhood Hits	233
SwissProt Accessions	Q96PQ1, Q8IYH7	Gene names	SIGLEC12, SIGLECL1, SLG
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 12 precursor (Siglec-12) (Sialic acid-binding Ig-like lectin-like 1) (Siglec-L1).

STK31_MOUSE
NC score	0.252658 (rank : 1030)	θ value	θ > 10 (rank : 3106)
Query Neighborhood Hits	2923	Target Neighborhood Hits	474	Shared Neighborhood Hits	409
SwissProt Accessions	Q99MW1	Gene names	Stk31
Domain Architecture
Description	Serine/threonine-protein kinase 31 (EC 2.7.11.1).

CILP2_HUMAN
NC score	0.249943 (rank : 1031)	θ value	4.1701e-05 (rank : 973)
Query Neighborhood Hits	2923	Target Neighborhood Hits	307	Shared Neighborhood Hits	211
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

PVRL3_MOUSE
NC score	0.248198 (rank : 1032)	θ value	7.59969e-07 (rank : 872)
Query Neighborhood Hits	2923	Target Neighborhood Hits	212	Shared Neighborhood Hits	203
SwissProt Accessions	Q9JLB9, Q9D006, Q9JLB7, Q9JLB8	Gene names	Pvrl3
Domain Architecture	No domain graphic available
Description	Poliovirus receptor-related protein 3 precursor (Cell adhesion molecule nectin-3) (Nectin-3) (CDw113 antigen).

LRFN4_HUMAN
NC score	0.247310 (rank : 1033)	θ value	5.81887e-07 (rank : 859)
Query Neighborhood Hits	2923	Target Neighborhood Hits	462	Shared Neighborhood Hits	252
SwissProt Accessions	Q6PJG9, Q9BWJ0	Gene names	LRFN4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursor.

IL6RB_HUMAN
NC score	0.246518 (rank : 1034)	θ value	2.13673e-09 (rank : 694)
Query Neighborhood Hits	2923	Target Neighborhood Hits	181	Shared Neighborhood Hits	152
SwissProt Accessions	P40189, Q9UQ41	Gene names	IL6ST
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin M receptor) (CD130 antigen) (CDw130).

SIGL6_HUMAN
NC score	0.246161 (rank : 1035)	θ value	0.000158464 (rank : 1022)
Query Neighborhood Hits	2923	Target Neighborhood Hits	233	Shared Neighborhood Hits	222
SwissProt Accessions	O43699, O15388, O43700	Gene names	SIGLEC6, CD33L, CD33L1, OBBP1
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 6 precursor (Siglec-6) (Obesity- binding protein 1) (OB-BP1) (CD33 antigen-like 1) (CDw327 antigen).

COCA1_MOUSE
NC score	0.242195 (rank : 1036)	θ value	3.76295e-14 (rank : 446)
Query Neighborhood Hits	2923	Target Neighborhood Hits	467	Shared Neighborhood Hits	259
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

LRFN2_MOUSE
NC score	0.241787 (rank : 1037)	θ value	2.61198e-07 (rank : 831)
Query Neighborhood Hits	2923	Target Neighborhood Hits	450	Shared Neighborhood Hits	246
SwissProt Accessions	Q80TG9, Q9CYK3	Gene names	Lrfn2, Kiaa1246
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 2 precursor.

LRFN2_HUMAN
NC score	0.241761 (rank : 1038)	θ value	5.81887e-07 (rank : 858)
Query Neighborhood Hits	2923	Target Neighborhood Hits	450	Shared Neighborhood Hits	243
SwissProt Accessions	Q9ULH4, Q5SYP9	Gene names	LRFN2, KIAA1246
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 2 precursor.

LRFN4_MOUSE
NC score	0.241525 (rank : 1039)	θ value	1.09739e-05 (rank : 935)
Query Neighborhood Hits	2923	Target Neighborhood Hits	442	Shared Neighborhood Hits	240
SwissProt Accessions	Q80XU8, Q3TQG8, Q8K3C4	Gene names	Lrfn4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursor.

PVRL3_HUMAN
NC score	0.240939 (rank : 1040)	θ value	1.69304e-06 (rank : 892)
Query Neighborhood Hits	2923	Target Neighborhood Hits	204	Shared Neighborhood Hits	193
SwissProt Accessions	Q9NQS3, Q6NVZ3, Q8WVU4, Q9BVA9, Q9Y412	Gene names	PVRL3, PRR3
Domain Architecture	No domain graphic available
Description	Poliovirus receptor-related protein 3 precursor (Nectin-3) (CDw113 antigen).

LRFN3_MOUSE
NC score	0.240488 (rank : 1041)	θ value	6.21693e-09 (rank : 729)
Query Neighborhood Hits	2923	Target Neighborhood Hits	455	Shared Neighborhood Hits	247
SwissProt Accessions	Q8BLY3	Gene names	Lrfn3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 3 precursor.

LRC21_MOUSE
NC score	0.232894 (rank : 1042)	θ value	2.44474e-05 (rank : 952)
Query Neighborhood Hits	2923	Target Neighborhood Hits	462	Shared Neighborhood Hits	262
SwissProt Accessions	Q8K099, Q8BXN3	Gene names	Lrrc21, Pal
Domain Architecture
Description	Leucine-rich repeat-containing protein 21 precursor (Photoreceptor- associated LRR superfamily protein) (Retina-specific protein PAL).

USH2A_HUMAN
NC score	0.232701 (rank : 1043)	θ value	2.27234e-27 (rank : 157)
Query Neighborhood Hits	2923	Target Neighborhood Hits	600	Shared Neighborhood Hits	236
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

NTKL_HUMAN
NC score	0.231568 (rank : 1044)	θ value	0.00509761 (rank : 1157)
Query Neighborhood Hits	2923	Target Neighborhood Hits	266	Shared Neighborhood Hits	231
SwissProt Accessions	Q96KG9, Q96G50, Q96KG8, Q96KH1, Q9HAW5, Q9HBL3, Q9NR53	Gene names	SCYL1, GKLP, NTKL, TAPK, TEIF, TRAP
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like protein (SCY1-like protein 1) (Teratoma- associated tyrosine kinase) (Telomerase transcriptional element- interacting factor) (Telomerase regulation-associated protein).

LRC21_HUMAN
NC score	0.230812 (rank : 1045)	θ value	2.44474e-05 (rank : 951)
Query Neighborhood Hits	2923	Target Neighborhood Hits	456	Shared Neighborhood Hits	257
SwissProt Accessions	Q9P2V4, Q9Y4N7	Gene names	LRRC21, PAL
Domain Architecture
Description	Leucine-rich repeat-containing protein 21 precursor (Photoreceptor- associated LRR superfamily protein) (Retina-specific protein PAL).

K2002_MOUSE
NC score	0.230269 (rank : 1046)	θ value	1.81305 (rank : 1949)
Query Neighborhood Hits	2923	Target Neighborhood Hits	267	Shared Neighborhood Hits	233
SwissProt Accessions	Q69Z38, Q8R365	Gene names	Kiaa2002
Domain Architecture	No domain graphic available
Description	Uncharacterized tyrosine-protein kinase KIAA2002 (EC 2.7.10.2).

COCA1_HUMAN
NC score	0.230266 (rank : 1047)	θ value	8.67504e-11 (rank : 611)
Query Neighborhood Hits	2923	Target Neighborhood Hits	458	Shared Neighborhood Hits	238
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

VRK3_HUMAN
NC score	0.229347 (rank : 1048)	θ value	0.0148317 (rank : 1226)
Query Neighborhood Hits	2923	Target Neighborhood Hits	349	Shared Neighborhood Hits	321
SwissProt Accessions	Q8IV63, Q9P2V8	Gene names	VRK3
Domain Architecture
Description	Serine/threonine-protein kinase VRK3 (EC 2.7.11.1) (Vaccinia-related kinase 3).

PVRL1_HUMAN
NC score	0.228840 (rank : 1049)	θ value	0.00665767 (rank : 1170)
Query Neighborhood Hits	2923	Target Neighborhood Hits	219	Shared Neighborhood Hits	192
SwissProt Accessions	Q15223, O75465, Q9HBE6, Q9HBW2	Gene names	PVRL1, HVEC, PRR1
Domain Architecture
Description	Poliovirus receptor-related protein 1 precursor (Herpes virus entry mediator C) (HveC) (Nectin-1) (Herpesvirus Ig-like receptor) (HIgR) (CD111 antigen).

LRFN3_HUMAN
NC score	0.228739 (rank : 1050)	θ value	8.97725e-08 (rank : 793)
Query Neighborhood Hits	2923	Target Neighborhood Hits	444	Shared Neighborhood Hits	234
SwissProt Accessions	Q9BTN0, Q6UY10	Gene names	LRFN3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 3 precursor.

IRPL2_HUMAN
NC score	0.228633 (rank : 1051)	θ value	8.97725e-08 (rank : 792)
Query Neighborhood Hits	2923	Target Neighborhood Hits	194	Shared Neighborhood Hits	163
SwissProt Accessions	Q9NP60, Q9NZN0	Gene names	IL1RAPL2, IL1R9
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 2 precursor (IL1RAPL-2-related protein) (Interleukin-1 receptor 9) (IL-1R9) (IL-1 receptor accessory protein-like 2) (Three immunoglobulin domain- containing IL-1 receptor-related 1) (TIGIRR-1).

LRFN5_MOUSE
NC score	0.228177 (rank : 1052)	θ value	3.08544e-08 (rank : 764)
Query Neighborhood Hits	2923	Target Neighborhood Hits	472	Shared Neighborhood Hits	253
SwissProt Accessions	Q8BXA0, Q8BJH4, Q8BZL0	Gene names	Lrfn5
Domain Architecture
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 5 precursor.

CD276_MOUSE
NC score	0.227886 (rank : 1053)	θ value	9.29e-05 (rank : 995)
Query Neighborhood Hits	2923	Target Neighborhood Hits	243	Shared Neighborhood Hits	214
SwissProt Accessions	Q8VE98	Gene names	Cd276, B7h3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3).

IRPL2_MOUSE
NC score	0.225322 (rank : 1054)	θ value	3.41135e-07 (rank : 842)
Query Neighborhood Hits	2923	Target Neighborhood Hits	195	Shared Neighborhood Hits	162
SwissProt Accessions	Q9ERS6, Q9ER66	Gene names	Il1rapl2
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 2 precursor (IL1RAPL-2-related protein) (TIGIRR-1).

IL6RB_MOUSE
NC score	0.224101 (rank : 1055)	θ value	2.36244e-08 (rank : 760)
Query Neighborhood Hits	2923	Target Neighborhood Hits	168	Shared Neighborhood Hits	147
SwissProt Accessions	Q00560	Gene names	Il6st
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (CD130 antigen).

USH2A_MOUSE
NC score	0.223892 (rank : 1056)	θ value	1.42661e-21 (rank : 232)
Query Neighborhood Hits	2923	Target Neighborhood Hits	626	Shared Neighborhood Hits	241
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

LRFN5_HUMAN
NC score	0.223303 (rank : 1057)	θ value	8.97725e-08 (rank : 794)
Query Neighborhood Hits	2923	Target Neighborhood Hits	464	Shared Neighborhood Hits	247
SwissProt Accessions	Q96NI6, Q86XL2	Gene names	LRFN5, C14orf146
Domain Architecture
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 5 precursor.

CILP1_MOUSE
NC score	0.221822 (rank : 1058)	θ value	9.29e-05 (rank : 997)
Query Neighborhood Hits	2923	Target Neighborhood Hits	282	Shared Neighborhood Hits	207
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

IRPL1_MOUSE
NC score	0.219995 (rank : 1059)	θ value	0.000121331 (rank : 1009)
Query Neighborhood Hits	2923	Target Neighborhood Hits	186	Shared Neighborhood Hits	175
SwissProt Accessions	P59823	Gene names	Il1rapl1
Domain Architecture	No domain graphic available
Description	X-linked interleukin-1 receptor accessory protein-like 1 precursor (IL1RAPL-1).

PVRL1_MOUSE
NC score	0.219652 (rank : 1060)	θ value	0.0330416 (rank : 1273)
Query Neighborhood Hits	2923	Target Neighborhood Hits	201	Shared Neighborhood Hits	183
SwissProt Accessions	Q9JKF6, Q9ERL5, Q9JI17	Gene names	Pvrl1, Hvec, Prr1
Domain Architecture
Description	Poliovirus receptor-related protein 1 precursor (Herpes virus entry mediator C) (HveC) (Nectin-1) (CD111 antigen).

IL1R2_MOUSE
NC score	0.218380 (rank : 1061)	θ value	9.29e-05 (rank : 1000)
Query Neighborhood Hits	2923	Target Neighborhood Hits	125	Shared Neighborhood Hits	117
SwissProt Accessions	P27931	Gene names	Il1r2, Il-1r2, Il1rb
Domain Architecture
Description	Interleukin-1 receptor type II precursor (IL-1R-2) (IL-1R-beta) (CD121b antigen).

PECA1_MOUSE
NC score	0.218127 (rank : 1062)	θ value	8.97725e-08 (rank : 796)
Query Neighborhood Hits	2923	Target Neighborhood Hits	126	Shared Neighborhood Hits	121
SwissProt Accessions	Q08481	Gene names	Pecam1, Pecam, Pecam-1
Domain Architecture
Description	Platelet endothelial cell adhesion molecule precursor (PECAM-1) (CD31 antigen).

PGFRL_HUMAN
NC score	0.217084 (rank : 1063)	θ value	3.41135e-07 (rank : 845)
Query Neighborhood Hits	2923	Target Neighborhood Hits	115	Shared Neighborhood Hits	113
SwissProt Accessions	Q15198, Q6FH04	Gene names	PDGFRL, PRLTS
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor receptor-like protein precursor (PDGF receptor beta-like tumor suppressor).

IRPL1_HUMAN
NC score	0.216282 (rank : 1064)	θ value	9.29e-05 (rank : 1001)
Query Neighborhood Hits	2923	Target Neighborhood Hits	196	Shared Neighborhood Hits	183
SwissProt Accessions	Q9NZN1, Q9UJ53	Gene names	IL1RAPL1, OPHN4
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 1 precursor (IL1RAPL-1) (Oligophrenin-4) (Three immunoglobulin domain-containing IL-1 receptor-related 2) (TIGIRR-2).

ITB4_HUMAN
NC score	0.215087 (rank : 1065)	θ value	8.67504e-11 (rank : 615)
Query Neighborhood Hits	2923	Target Neighborhood Hits	458	Shared Neighborhood Hits	211
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

EMB_MOUSE
NC score	0.210042 (rank : 1066)	θ value	1.80886e-08 (rank : 756)
Query Neighborhood Hits	2923	Target Neighborhood Hits	83	Shared Neighborhood Hits	82
SwissProt Accessions	P21995, Q3UFF1, Q8C2J8, Q8C543, Q96C38	Gene names	Emb, Gp70
Domain Architecture
Description	Embigin precursor (Teratocarcinoma glycoprotein Gp-70).

CILP1_HUMAN
NC score	0.209284 (rank : 1067)	θ value	4.92598e-06 (rank : 910)
Query Neighborhood Hits	2923	Target Neighborhood Hits	266	Shared Neighborhood Hits	184
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

CEAM7_HUMAN
NC score	0.207693 (rank : 1068)	θ value	0.000786445 (rank : 1071)
Query Neighborhood Hits	2923	Target Neighborhood Hits	170	Shared Neighborhood Hits	163
SwissProt Accessions	Q14002, O15148, O15149, Q13983, Q9UPJ2	Gene names	CEACAM7, CGM2
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 7 precursor (Carcinoembryonic antigen CGM2).

LRRN3_HUMAN
NC score	0.207371 (rank : 1069)	θ value	1.87187e-05 (rank : 947)
Query Neighborhood Hits	2923	Target Neighborhood Hits	461	Shared Neighborhood Hits	249
SwissProt Accessions	Q9H3W5, O43377, Q6I9V8, Q8IYQ6	Gene names	LRRN3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 3 precursor (Neuronal leucine- rich repeat protein 3) (NLRR-3).

VRK3_MOUSE
NC score	0.206706 (rank : 1070)	θ value	1.06291 (rank : 1816)
Query Neighborhood Hits	2923	Target Neighborhood Hits	342	Shared Neighborhood Hits	320
SwissProt Accessions	Q8K3G5, Q921W6	Gene names	Vrk3
Domain Architecture
Description	Serine/threonine-protein kinase VRK3 (EC 2.7.11.1) (Vaccinia-related kinase 3).

UNC5D_MOUSE
NC score	0.205157 (rank : 1071)	θ value	2.44474e-05 (rank : 962)
Query Neighborhood Hits	2923	Target Neighborhood Hits	268	Shared Neighborhood Hits	192
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

PDL1_HUMAN
NC score	0.204748 (rank : 1072)	θ value	0.00869519 (rank : 1186)
Query Neighborhood Hits	2923	Target Neighborhood Hits	195	Shared Neighborhood Hits	175
SwissProt Accessions	Q9NZQ7, Q66RK1, Q6WEX4, Q9NUZ5	Gene names	CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

LRRN1_HUMAN
NC score	0.204646 (rank : 1073)	θ value	2.44474e-05 (rank : 953)
Query Neighborhood Hits	2923	Target Neighborhood Hits	518	Shared Neighborhood Hits	289
SwissProt Accessions	Q6UXK5, Q3LID5, Q8IYV5, Q9H8V1, Q9P231	Gene names	LRRN1, KIAA1497
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 1 precursor (Neuronal leucine- rich repeat protein 1) (NLRR-1).

PVR_HUMAN
NC score	0.204491 (rank : 1074)	θ value	0.00035302 (rank : 1048)
Query Neighborhood Hits	2923	Target Neighborhood Hits	195	Shared Neighborhood Hits	168
SwissProt Accessions	P15151, P15152, Q15267, Q15268, Q96BJ1	Gene names	PVR, PVS
Domain Architecture
Description	Poliovirus receptor precursor (Nectin-like protein 5) (Necl-5) (CD155 antigen).

COEA1_MOUSE
NC score	0.203583 (rank : 1075)	θ value	6.64225e-11 (rank : 601)
Query Neighborhood Hits	2923	Target Neighborhood Hits	402	Shared Neighborhood Hits	202
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

I12R2_HUMAN
NC score	0.203503 (rank : 1076)	θ value	1.69304e-06 (rank : 891)
Query Neighborhood Hits	2923	Target Neighborhood Hits	163	Shared Neighborhood Hits	134
SwissProt Accessions	Q99665	Gene names	IL12RB2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

UNC5D_HUMAN
NC score	0.202630 (rank : 1077)	θ value	2.44474e-05 (rank : 961)
Query Neighborhood Hits	2923	Target Neighborhood Hits	267	Shared Neighborhood Hits	191
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

PIGR_MOUSE
NC score	0.202187 (rank : 1078)	θ value	0.00035302 (rank : 1047)
Query Neighborhood Hits	2923	Target Neighborhood Hits	214	Shared Neighborhood Hits	172
SwissProt Accessions	O70570	Gene names	Pigr
Domain Architecture
Description	Polymeric-immunoglobulin receptor precursor (Poly-Ig receptor) (PIGR) [Contains: Secretory component].

I12R2_MOUSE
NC score	0.201779 (rank : 1079)	θ value	2.44474e-05 (rank : 950)
Query Neighborhood Hits	2923	Target Neighborhood Hits	143	Shared Neighborhood Hits	127
SwissProt Accessions	P97378	Gene names	Il12rb2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

SIGL7_HUMAN
NC score	0.201278 (rank : 1080)	θ value	0.000602161 (rank : 1069)
Query Neighborhood Hits	2923	Target Neighborhood Hits	180	Shared Neighborhood Hits	166
SwissProt Accessions	Q9Y286, Q9NZQ1, Q9UJ86, Q9UJ87, Q9Y502	Gene names	SIGLEC7, AIRM1
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 7 precursor (Siglec-7) (QA79 membrane protein) (Adhesion inhibitory receptor molecule 1) (AIRM-1) (p75) (D-siglec) (CDw328 antigen).

TENN_MOUSE
NC score	0.200909 (rank : 1081)	θ value	2.59989e-23 (rank : 202)
Query Neighborhood Hits	2923	Target Neighborhood Hits	484	Shared Neighborhood Hits	190
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

LIFR_HUMAN
NC score	0.198629 (rank : 1082)	θ value	4.1701e-05 (rank : 977)
Query Neighborhood Hits	2923	Target Neighborhood Hits	130	Shared Neighborhood Hits	108
SwissProt Accessions	P42702, Q6LCD9	Gene names	LIFR
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (CD118 antigen).

PVRL2_MOUSE
NC score	0.198230 (rank : 1083)	θ value	0.00134147 (rank : 1096)
Query Neighborhood Hits	2923	Target Neighborhood Hits	242	Shared Neighborhood Hits	166
SwissProt Accessions	P32507, Q62096	Gene names	Pvrl2, Mph, Pvr, Pvs
Domain Architecture
Description	Poliovirus receptor-related protein 2 precursor (Murine herpesvirus entry protein B) (mHveB) (Nectin-2) (Poliovirus receptor homolog) (CD112 antigen).

IL1R1_HUMAN
NC score	0.197708 (rank : 1084)	θ value	5.81887e-07 (rank : 855)
Query Neighborhood Hits	2923	Target Neighborhood Hits	140	Shared Neighborhood Hits	132
SwissProt Accessions	P14778	Gene names	IL1R1, IL1R, IL1RA, IL1RT1
Domain Architecture
Description	Interleukin-1 receptor type I precursor (IL-1R-1) (IL-1RT1) (IL-1R- alpha) (p80) (CD121a antigen).

LRRN1_MOUSE
NC score	0.197539 (rank : 1085)	θ value	0.000121331 (rank : 1010)
Query Neighborhood Hits	2923	Target Neighborhood Hits	508	Shared Neighborhood Hits	282
SwissProt Accessions	Q61809, Q3USY1, Q69ZI0	Gene names	Lrrn1, Kiaa1497
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 1 precursor (Neuronal leucine- rich repeat protein 1) (NLRR-1).

TENR_HUMAN
NC score	0.197371 (rank : 1086)	θ value	5.60996e-18 (rank : 331)
Query Neighborhood Hits	2923	Target Neighborhood Hits	526	Shared Neighborhood Hits	209
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

LRRN3_MOUSE
NC score	0.196503 (rank : 1087)	θ value	3.19293e-05 (rank : 965)
Query Neighborhood Hits	2923	Target Neighborhood Hits	455	Shared Neighborhood Hits	245
SwissProt Accessions	Q8CBC6, P97860	Gene names	Lrrn3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 3 precursor (Neuronal leucine- rich repeat protein 3) (NLRR-3).

LRRN5_HUMAN
NC score	0.196355 (rank : 1088)	θ value	3.77169e-06 (rank : 908)
Query Neighborhood Hits	2923	Target Neighborhood Hits	493	Shared Neighborhood Hits	266
SwissProt Accessions	O75325, Q5T0Y0, Q6UXM0, Q8N182	Gene names	LRRN5, GAC1, LRRN2
Domain Architecture
Description	Leucine-rich repeats neuronal protein 5 precursor (Glioma amplified on chromosome 1 protein).

ILRL2_MOUSE
NC score	0.193958 (rank : 1089)	θ value	5.81887e-07 (rank : 856)
Query Neighborhood Hits	2923	Target Neighborhood Hits	158	Shared Neighborhood Hits	152
SwissProt Accessions	Q9ERS7	Gene names	Il1rl2
Domain Architecture
Description	Interleukin-1 receptor-like 2 precursor (IL-1Rrp2).

TENR_MOUSE
NC score	0.193237 (rank : 1090)	θ value	4.9032e-22 (rank : 221)
Query Neighborhood Hits	2923	Target Neighborhood Hits	531	Shared Neighborhood Hits	211
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

MOX2R_MOUSE
NC score	0.191910 (rank : 1091)	θ value	0.0148317 (rank : 1219)
Query Neighborhood Hits	2923	Target Neighborhood Hits	110	Shared Neighborhood Hits	107
SwissProt Accessions	Q9ES57	Gene names	Cd200r1, Mox2r, Ox2r
Domain Architecture	No domain graphic available
Description	Cell surface glycoprotein OX2 receptor precursor (CD200 cell surface glycoprotein receptor).

SIG12_MOUSE
NC score	0.191581 (rank : 1092)	θ value	0.00020696 (rank : 1034)
Query Neighborhood Hits	2923	Target Neighborhood Hits	225	Shared Neighborhood Hits	191
SwissProt Accessions	Q91Y57	Gene names	Siglec12, Siglec5, Siglece, Siglecl1
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 12 precursor (Siglec-12) (Sialic acid-binding Ig-like lectin-like 1) (Siglec-L1) (Sialic acid-binding Ig-like lectin 5) (Siglec-5) (mSiglec-E) (Myeloid inhibitory siglec) (MIS).

LIFR_MOUSE
NC score	0.191204 (rank : 1093)	θ value	0.00228821 (rank : 1119)
Query Neighborhood Hits	2923	Target Neighborhood Hits	127	Shared Neighborhood Hits	108
SwissProt Accessions	P42703	Gene names	Lifr
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (D-factor/LIF receptor) (CD118 antigen).

PGFRL_MOUSE
NC score	0.190734 (rank : 1094)	θ value	0.00102713 (rank : 1090)
Query Neighborhood Hits	2923	Target Neighborhood Hits	106	Shared Neighborhood Hits	100
SwissProt Accessions	Q6PE55, Q3V182, Q9D0Z1	Gene names	Pdgfrl
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor receptor-like protein precursor.

TARSH_HUMAN
NC score	0.190086 (rank : 1095)	θ value	3.19293e-05 (rank : 969)
Query Neighborhood Hits	2923	Target Neighborhood Hits	768	Shared Neighborhood Hits	381
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

FCERA_HUMAN
NC score	0.189992 (rank : 1096)	θ value	8.40245e-06 (rank : 924)
Query Neighborhood Hits	2923	Target Neighborhood Hits	150	Shared Neighborhood Hits	137
SwissProt Accessions	P12319	Gene names	FCER1A, FCE1A
Domain Architecture
Description	High affinity immunoglobulin epsilon receptor alpha-subunit precursor (FcERI) (IgE Fc receptor, alpha-subunit) (Fc-epsilon RI-alpha).

FCGR1_HUMAN
NC score	0.189781 (rank : 1097)	θ value	1.38499e-08 (rank : 747)
Query Neighborhood Hits	2923	Target Neighborhood Hits	145	Shared Neighborhood Hits	126
SwissProt Accessions	P12314, P12315, Q92495, Q92663	Gene names	FCGR1A, FCG1, FCGR1, IGFR1
Domain Architecture
Description	High affinity immunoglobulin gamma Fc receptor I precursor (Fc-gamma RI) (FcRI) (IgG Fc receptor I) (CD64 antigen).

PTPRM_HUMAN
NC score	0.185969 (rank : 1098)	θ value	1.17247e-07 (rank : 811)
Query Neighborhood Hits	2923	Target Neighborhood Hits	244	Shared Neighborhood Hits	178
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

HCFC2_MOUSE
NC score	0.184776 (rank : 1099)	θ value	0.000158464 (rank : 1017)
Query Neighborhood Hits	2923	Target Neighborhood Hits	97	Shared Neighborhood Hits	95
SwissProt Accessions	Q9D968	Gene names	Hcfc2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

PVRL2_HUMAN
NC score	0.184735 (rank : 1100)	θ value	0.00665767 (rank : 1171)
Query Neighborhood Hits	2923	Target Neighborhood Hits	185	Shared Neighborhood Hits	148
SwissProt Accessions	Q92692, O75455, Q96J29	Gene names	PVRL2, HVEB, PRR2
Domain Architecture
Description	Poliovirus receptor-related protein 2 precursor (Herpes virus entry mediator B) (HveB) (Nectin-2) (CD112 antigen).

PTPRM_MOUSE
NC score	0.182172 (rank : 1101)	θ value	4.92598e-06 (rank : 914)
Query Neighborhood Hits	2923	Target Neighborhood Hits	238	Shared Neighborhood Hits	175
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

TENN_HUMAN
NC score	0.181253 (rank : 1102)	θ value	1.5773e-20 (rank : 254)
Query Neighborhood Hits	2923	Target Neighborhood Hits	453	Shared Neighborhood Hits	178
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

IL1R1_MOUSE
NC score	0.181196 (rank : 1103)	θ value	0.000602161 (rank : 1065)
Query Neighborhood Hits	2923	Target Neighborhood Hits	142	Shared Neighborhood Hits	133
SwissProt Accessions	P13504	Gene names	Il1r1, Il-1r1, Il1ra
Domain Architecture
Description	Interleukin-1 receptor type I precursor (IL-1R-1) (p80) (CD121a antigen).

COEA1_HUMAN
NC score	0.180134 (rank : 1104)	θ value	6.64225e-11 (rank : 600)
Query Neighborhood Hits	2923	Target Neighborhood Hits	427	Shared Neighborhood Hits	208
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

PIGR_HUMAN
NC score	0.179575 (rank : 1105)	θ value	0.000602161 (rank : 1067)
Query Neighborhood Hits	2923	Target Neighborhood Hits	164	Shared Neighborhood Hits	135
SwissProt Accessions	P01833, Q8IZY7	Gene names	PIGR
Domain Architecture
Description	Polymeric-immunoglobulin receptor precursor (Poly-Ig receptor) (PIGR) (Hepatocellular carcinoma-associated protein TB6) [Contains: Secretory component].

KALM_HUMAN
NC score	0.177265 (rank : 1106)	θ value	0.00020696 (rank : 1033)
Query Neighborhood Hits	2923	Target Neighborhood Hits	114	Shared Neighborhood Hits	83
SwissProt Accessions	P23352	Gene names	KAL1, ADMLX, KAL, KALIG1
Domain Architecture
Description	Anosmin-1 precursor (Kallmann syndrome protein) (Adhesion molecule- like X-linked).

ILRL1_HUMAN
NC score	0.176397 (rank : 1107)	θ value	0.00035302 (rank : 1043)
Query Neighborhood Hits	2923	Target Neighborhood Hits	167	Shared Neighborhood Hits	141
SwissProt Accessions	Q01638, Q53TU7, Q8NEJ3, Q9ULV7, Q9UQ44	Gene names	IL1RL1, DER4, ST2, T1
Domain Architecture
Description	Interleukin-1 receptor-like 1 precursor (ST2 protein).

PDL1_MOUSE
NC score	0.176062 (rank : 1108)	θ value	0.00102713 (rank : 1089)
Query Neighborhood Hits	2923	Target Neighborhood Hits	168	Shared Neighborhood Hits	153
SwissProt Accessions	Q9EP73	Gene names	Cd274, B7h1, Pdcd1l1, Pdcd1lg1, Pdl1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

CO7A1_HUMAN
NC score	0.172273 (rank : 1109)	θ value	1.58096e-12 (rank : 512)
Query Neighborhood Hits	2923	Target Neighborhood Hits	807	Shared Neighborhood Hits	313
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

IGS21_HUMAN
NC score	0.172017 (rank : 1110)	θ value	0.0113563 (rank : 1201)
Query Neighborhood Hits	2923	Target Neighborhood Hits	123	Shared Neighborhood Hits	118
SwissProt Accessions	Q96ID5, Q8NBR8	Gene names	IGSF21
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 21 precursor.

LRC24_HUMAN
NC score	0.171852 (rank : 1111)	θ value	0.00175202 (rank : 1104)
Query Neighborhood Hits	2923	Target Neighborhood Hits	404	Shared Neighborhood Hits	214
SwissProt Accessions	Q50LG9	Gene names	LRRC24
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 24 precursor.

PDL2_MOUSE
NC score	0.171443 (rank : 1112)	θ value	0.00175202 (rank : 1106)
Query Neighborhood Hits	2923	Target Neighborhood Hits	116	Shared Neighborhood Hits	110
SwissProt Accessions	Q9WUL5	Gene names	Pdcd1lg2, B7dc, Btdc, Cd273, Pdl2
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 2 precursor (Programmed death ligand 2) (PD-L2) (PD-1-ligand 2) (PDCD1 ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD273 antigen).

IGS21_MOUSE
NC score	0.171421 (rank : 1113)	θ value	0.0113563 (rank : 1202)
Query Neighborhood Hits	2923	Target Neighborhood Hits	118	Shared Neighborhood Hits	113
SwissProt Accessions	Q7TNR6	Gene names	Igsf21
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 21 precursor.

CSF3R_HUMAN
NC score	0.167531 (rank : 1114)	θ value	0.365318 (rank : 1545)
Query Neighborhood Hits	2923	Target Neighborhood Hits	140	Shared Neighborhood Hits	120
SwissProt Accessions	Q99062	Gene names	CSF3R, GCSFR
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

COKA1_HUMAN
NC score	0.166636 (rank : 1115)	θ value	1.80886e-08 (rank : 754)
Query Neighborhood Hits	2923	Target Neighborhood Hits	403	Shared Neighborhood Hits	180
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

FCGR1_MOUSE
NC score	0.166065 (rank : 1116)	θ value	7.1131e-05 (rank : 989)
Query Neighborhood Hits	2923	Target Neighborhood Hits	123	Shared Neighborhood Hits	112
SwissProt Accessions	P26151	Gene names	Fcgr1, Fcg1
Domain Architecture
Description	High affinity immunoglobulin gamma Fc receptor I precursor (Fc-gamma RI) (FcRI) (IgG Fc receptor I).

NGL1_MOUSE
NC score	0.165038 (rank : 1117)	θ value	2.21117e-06 (rank : 896)
Query Neighborhood Hits	2923	Target Neighborhood Hits	512	Shared Neighborhood Hits	274
SwissProt Accessions	Q8C031, Q8BGH8	Gene names	Lrrc4c, Ngl1
Domain Architecture	No domain graphic available
Description	Netrin-G1 ligand precursor (NGL-1) (Leucine-rich repeat-containing protein 4C).

LRC4B_MOUSE
NC score	0.164843 (rank : 1118)	θ value	8.40245e-06 (rank : 927)
Query Neighborhood Hits	2923	Target Neighborhood Hits	484	Shared Neighborhood Hits	258
SwissProt Accessions	P0C192	Gene names	Lrrc4b, Lrig4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4B precursor.

NGL1_HUMAN
NC score	0.164808 (rank : 1119)	θ value	2.21117e-06 (rank : 895)
Query Neighborhood Hits	2923	Target Neighborhood Hits	511	Shared Neighborhood Hits	273
SwissProt Accessions	Q9HCJ2, Q7L0N3	Gene names	LRRC4C, KIAA1580, NGL1
Domain Architecture	No domain graphic available
Description	Netrin-G1 ligand precursor (NGL-1) (Leucine-rich repeat-containing protein 4C).

UNC5A_HUMAN
NC score	0.164245 (rank : 1120)	θ value	0.000461057 (rank : 1060)
Query Neighborhood Hits	2923	Target Neighborhood Hits	198	Shared Neighborhood Hits	132
SwissProt Accessions	Q6ZN44, Q8TF26, Q96GP4	Gene names	UNC5A, KIAA1976, UNC5H1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

PTPRT_MOUSE
NC score	0.164220 (rank : 1121)	θ value	5.44631e-05 (rank : 984)
Query Neighborhood Hits	2923	Target Neighborhood Hits	219	Shared Neighborhood Hits	151
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

PTPRT_HUMAN
NC score	0.163531 (rank : 1122)	θ value	5.44631e-05 (rank : 983)
Query Neighborhood Hits	2923	Target Neighborhood Hits	217	Shared Neighborhood Hits	152
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

LRC4B_HUMAN
NC score	0.163137 (rank : 1123)	θ value	8.40245e-06 (rank : 926)
Query Neighborhood Hits	2923	Target Neighborhood Hits	479	Shared Neighborhood Hits	252
SwissProt Accessions	Q9NT99, Q3ZCQ4, Q58F20	Gene names	LRRC4B, LRIG4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4B precursor.

UNC5C_MOUSE
NC score	0.161630 (rank : 1124)	θ value	0.000786445 (rank : 1078)
Query Neighborhood Hits	2923	Target Neighborhood Hits	225	Shared Neighborhood Hits	148
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

TENX_HUMAN
NC score	0.161443 (rank : 1125)	θ value	6.17384e-33 (rank : 110)
Query Neighborhood Hits	2923	Target Neighborhood Hits	789	Shared Neighborhood Hits	255
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

UNC5C_HUMAN
NC score	0.160107 (rank : 1126)	θ value	0.00175202 (rank : 1111)
Query Neighborhood Hits	2923	Target Neighborhood Hits	226	Shared Neighborhood Hits	143
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

PTPRU_HUMAN
NC score	0.159438 (rank : 1127)	θ value	0.00298849 (rank : 1130)
Query Neighborhood Hits	2923	Target Neighborhood Hits	237	Shared Neighborhood Hits	172
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

LAG3_MOUSE
NC score	0.157076 (rank : 1128)	θ value	0.00298849 (rank : 1127)
Query Neighborhood Hits	2923	Target Neighborhood Hits	117	Shared Neighborhood Hits	104
SwissProt Accessions	Q61790, Q0VBL2	Gene names	Lag3
Domain Architecture
Description	Lymphocyte activation gene 3 protein precursor (LAG-3) (CD223 antigen).

LRC24_MOUSE
NC score	0.157034 (rank : 1129)	θ value	0.00509761 (rank : 1154)
Query Neighborhood Hits	2923	Target Neighborhood Hits	387	Shared Neighborhood Hits	211
SwissProt Accessions	Q8BHA1	Gene names	Lrrc24
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 24 precursor.

JAML1_MOUSE
NC score	0.156881 (rank : 1130)	θ value	0.0252991 (rank : 1253)
Query Neighborhood Hits	2923	Target Neighborhood Hits	185	Shared Neighborhood Hits	153
SwissProt Accessions	Q80UL9, Q5DTC4	Gene names	Amica1, Gm638, Jaml
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule-like precursor (mCrea7).

HHLA2_HUMAN
NC score	0.155925 (rank : 1131)	θ value	0.00175202 (rank : 1102)
Query Neighborhood Hits	2923	Target Neighborhood Hits	140	Shared Neighborhood Hits	119
SwissProt Accessions	Q9UM44, Q9NWQ6	Gene names	HHLA2
Domain Architecture	No domain graphic available
Description	HERV-H LTR-associating protein 2 precursor (Human endogenous retrovirus-H long terminal repeat-associating protein 2).

FCG2B_HUMAN
NC score	0.154460 (rank : 1132)	θ value	2.88788e-06 (rank : 899)
Query Neighborhood Hits	2923	Target Neighborhood Hits	116	Shared Neighborhood Hits	102
SwissProt Accessions	P31994, O95649, Q53X85, Q5VXA9, Q8NIA1	Gene names	FCGR2B, CD32, FCG2, IGFR2
Domain Architecture
Description	Low affinity immunoglobulin gamma Fc region receptor II-b precursor (Fc-gamma RII-b) (FcRII-b) (IgG Fc receptor II-b) (Fc-gamma-RIIb) (CD32 antigen) (CDw32).

UNC5B_HUMAN
NC score	0.153968 (rank : 1133)	θ value	0.00134147 (rank : 1097)
Query Neighborhood Hits	2923	Target Neighborhood Hits	225	Shared Neighborhood Hits	147
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

FCG2C_HUMAN
NC score	0.153735 (rank : 1134)	θ value	2.88788e-06 (rank : 900)
Query Neighborhood Hits	2923	Target Neighborhood Hits	118	Shared Neighborhood Hits	103
SwissProt Accessions	P31995, O00523, O00524, O00525	Gene names	FCGR2C, CD32, FCG2, IGFR2
Domain Architecture
Description	Low affinity immunoglobulin gamma Fc region receptor II-c precursor (Fc-gamma RII-c) (FcRII-c) (IgG Fc receptor II-c) (Fc-gamma-RIIc) (CD32 antigen) (CDw32).

CD80_MOUSE
NC score	0.151763 (rank : 1135)	θ value	0.279714 (rank : 1486)
Query Neighborhood Hits	2923	Target Neighborhood Hits	136	Shared Neighborhood Hits	126
SwissProt Accessions	Q00609, Q61332	Gene names	Cd80, B7
Domain Architecture
Description	T-lymphocyte activation antigen CD80 precursor (Activation B7-1 antigen) (B7).

UNC5B_MOUSE
NC score	0.151471 (rank : 1136)	θ value	0.00134147 (rank : 1098)
Query Neighborhood Hits	2923	Target Neighborhood Hits	226	Shared Neighborhood Hits	145
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

TENA_HUMAN
NC score	0.149852 (rank : 1137)	θ value	2.20094e-22 (rank : 213)
Query Neighborhood Hits	2923	Target Neighborhood Hits	631	Shared Neighborhood Hits	203
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

PTPRK_MOUSE
NC score	0.148822 (rank : 1138)	θ value	9.29e-05 (rank : 1004)
Query Neighborhood Hits	2923	Target Neighborhood Hits	223	Shared Neighborhood Hits	154
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRK_HUMAN
NC score	0.147044 (rank : 1139)	θ value	3.19293e-05 (rank : 966)
Query Neighborhood Hits	2923	Target Neighborhood Hits	228	Shared Neighborhood Hits	158
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

UNC5A_MOUSE
NC score	0.146844 (rank : 1140)	θ value	0.00020696 (rank : 1036)
Query Neighborhood Hits	2923	Target Neighborhood Hits	203	Shared Neighborhood Hits	131
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

ILRL1_MOUSE
NC score	0.146257 (rank : 1141)	θ value	0.0736092 (rank : 1341)
Query Neighborhood Hits	2923	Target Neighborhood Hits	172	Shared Neighborhood Hits	144
SwissProt Accessions	P14719, Q05208	Gene names	Il1rl1, Ly84, St2, Ste2
Domain Architecture
Description	Interleukin-1 receptor-like 1 precursor (ST2 protein) (T1 protein) (Lymphocyte antigen 84).

PXK_MOUSE
NC score	0.145253 (rank : 1142)	θ value	θ > 10 (rank : 3078)
Query Neighborhood Hits	2923	Target Neighborhood Hits	320	Shared Neighborhood Hits	229
SwissProt Accessions	Q8BX57, Q3TD60, Q3TEL7, Q3TZZ1, Q3U197, Q3U773, Q3UCS5, Q4FBH7, Q91WB6	Gene names	Pxk
Domain Architecture	No domain graphic available
Description	PX domain-containing protein kinase-like protein (Modulator of Na,K- ATPase) (MONaKA).

LRRC4_HUMAN
NC score	0.144698 (rank : 1143)	θ value	7.59969e-07 (rank : 869)
Query Neighborhood Hits	2923	Target Neighborhood Hits	444	Shared Neighborhood Hits	225
SwissProt Accessions	Q9HBW1, Q6ZMI8, Q96A85	Gene names	LRRC4, BAG
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4 precursor (Brain tumor- associated protein LRRC4) (NAG14).

CD80_HUMAN
NC score	0.143724 (rank : 1144)	θ value	0.62314 (rank : 1656)
Query Neighborhood Hits	2923	Target Neighborhood Hits	129	Shared Neighborhood Hits	120
SwissProt Accessions	P33681	Gene names	CD80, CD28LG, CD28LG1, LAB7
Domain Architecture
Description	T-lymphocyte activation antigen CD80 precursor (Activation B7-1 antigen) (CTLA-4 counter-receptor B7.1) (B7) (BB1).

EMB_HUMAN
NC score	0.143723 (rank : 1145)	θ value	2.88788e-06 (rank : 898)
Query Neighborhood Hits	2923	Target Neighborhood Hits	54	Shared Neighborhood Hits	49
SwissProt Accessions	Q6PCB8	Gene names	EMB
Domain Architecture	No domain graphic available
Description	Embigin precursor.

LAG3_HUMAN
NC score	0.141661 (rank : 1146)	θ value	0.000158464 (rank : 1018)
Query Neighborhood Hits	2923	Target Neighborhood Hits	129	Shared Neighborhood Hits	100
SwissProt Accessions	P18627	Gene names	LAG3, FDC
Domain Architecture
Description	Lymphocyte activation gene 3 protein precursor (LAG-3) (FDC protein) (CD223 antigen).

OX2G_MOUSE
NC score	0.140144 (rank : 1147)	θ value	0.125558 (rank : 1396)
Query Neighborhood Hits	2923	Target Neighborhood Hits	105	Shared Neighborhood Hits	101
SwissProt Accessions	O54901, O54816, Q9JHD5	Gene names	Cd200, Mox2
Domain Architecture
Description	OX-2 membrane glycoprotein precursor (MRC OX-2 antigen) (CD200 antigen).

PDL2_HUMAN
NC score	0.140003 (rank : 1148)	θ value	0.0961366 (rank : 1377)
Query Neighborhood Hits	2923	Target Neighborhood Hits	114	Shared Neighborhood Hits	107
SwissProt Accessions	Q9BQ51, Q5T7Z6, Q6JXL8, Q6JXL9	Gene names	PDCD1LG2, B7DC, CD273, PDCD1L2, PDL2
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 2 precursor (Programmed death ligand 2) (PD-L2) (PD-1-ligand 2) (PDCD1 ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD273 antigen).

FCG2A_HUMAN
NC score	0.139510 (rank : 1149)	θ value	1.69304e-06 (rank : 890)
Query Neighborhood Hits	2923	Target Neighborhood Hits	92	Shared Neighborhood Hits	88
SwissProt Accessions	P12318	Gene names	FCGR2A, CD32, FCG2, IGFR2
Domain Architecture
Description	Low affinity immunoglobulin gamma Fc region receptor II-a precursor (Fc-gamma RII-a) (FcRII-a) (IgG Fc receptor II-a) (Fc-gamma-RIIa) (CD32 antigen) (CDw32).

SORL_HUMAN
NC score	0.139053 (rank : 1150)	θ value	8.97725e-08 (rank : 797)
Query Neighborhood Hits	2923	Target Neighborhood Hits	440	Shared Neighborhood Hits	165
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

TENA_MOUSE
NC score	0.138810 (rank : 1151)	θ value	2.0648e-12 (rank : 530)
Query Neighborhood Hits	2923	Target Neighborhood Hits	596	Shared Neighborhood Hits	188
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

CSF3R_MOUSE
NC score	0.137630 (rank : 1152)	θ value	0.0148317 (rank : 1215)
Query Neighborhood Hits	2923	Target Neighborhood Hits	104	Shared Neighborhood Hits	96
SwissProt Accessions	P40223	Gene names	Csf3r, Csfgr
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

SORL_MOUSE
NC score	0.136217 (rank : 1153)	θ value	8.97725e-08 (rank : 798)
Query Neighborhood Hits	2923	Target Neighborhood Hits	439	Shared Neighborhood Hits	167
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

ILRL2_HUMAN
NC score	0.134851 (rank : 1154)	θ value	0.00035302 (rank : 1044)
Query Neighborhood Hits	2923	Target Neighborhood Hits	112	Shared Neighborhood Hits	105
SwissProt Accessions	Q9HB29, Q13525, Q45H74	Gene names	IL1RL2, IL1RRP2
Domain Architecture
Description	Interleukin-1 receptor-like 2 precursor (IL-1Rrp2) (Interleukin-1 receptor-related protein 2) (IL1R-rp2).

SHPS1_HUMAN
NC score	0.131903 (rank : 1155)	θ value	0.000158464 (rank : 1021)
Query Neighborhood Hits	2923	Target Neighborhood Hits	455	Shared Neighborhood Hits	208
SwissProt Accessions	P78324, O00683, O43799, Q8N517, Q8TAL8, Q9H0Z2, Q9UDX2, Q9UIJ6, Q9Y4U9	Gene names	SIRPA, BIT, MFR, MYD1, PTPNS1, SHPS1, SIRP
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type substrate 1 precursor (SHP substrate 1) (SHPS-1) (Inhibitory receptor SHPS-1) (Signal- regulatory protein alpha-1) (Sirp-alpha-1) (Sirp-alpha-2) (Sirp-alpha- 3) (MyD-1 antigen) (Brain Ig-like molecule with tyrosine-based activation motifs) (Bit) (Macrophage fusion receptor) (p84) (CD172a antigen).

PTPRB_HUMAN
NC score	0.131215 (rank : 1156)	θ value	1.87187e-05 (rank : 948)
Query Neighborhood Hits	2923	Target Neighborhood Hits	242	Shared Neighborhood Hits	132
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

FCRLA_MOUSE
NC score	0.131117 (rank : 1157)	θ value	0.0736092 (rank : 1334)
Query Neighborhood Hits	2923	Target Neighborhood Hits	110	Shared Neighborhood Hits	91
SwissProt Accessions	Q920A9, Q3T9Q2, Q8K3U9, Q8VHP5	Gene names	Fcrla, Fcrl, Fcrl1, Fcrlm1, Fcrx, Freb
Domain Architecture	No domain graphic available
Description	Fc receptor-like and mucin-like 1 precursor (Fc receptor-like A) (Fc receptor homolog expressed in B-cells) (Fc receptor-related protein X) (FcRX) (Fc receptor-like protein).

FCRLA_HUMAN
NC score	0.129410 (rank : 1158)	θ value	0.00665767 (rank : 1163)
Query Neighborhood Hits	2923	Target Neighborhood Hits	135	Shared Neighborhood Hits	102
SwissProt Accessions	Q7L513, Q5VXA1, Q5VXA2, Q5VXA3, Q5VXB0, Q8NEW4, Q8WXH3, Q96PC6, Q96PJ0, Q96PJ1, Q96PJ2, Q96PJ4, Q9BR57	Gene names	FCRLA, FCRL, FCRL1, FCRLM1, FCRX, FREB
Domain Architecture	No domain graphic available
Description	Fc receptor-like and mucin-like 1 precursor (Fc receptor-like A) (Fc receptor homolog expressed in B-cells) (Fc receptor-related protein X) (FcRX) (Fc receptor-like protein).

ICAM1_MOUSE
NC score	0.128951 (rank : 1159)	θ value	0.00869519 (rank : 1178)
Query Neighborhood Hits	2923	Target Neighborhood Hits	99	Shared Neighborhood Hits	91
SwissProt Accessions	P13597, Q61828	Gene names	Icam1, Icam-1
Domain Architecture
Description	Intercellular adhesion molecule 1 precursor (ICAM-1) (MALA-2).

PRAX_HUMAN
NC score	0.128730 (rank : 1160)	θ value	1.20211e-36 (rank : 76)
Query Neighborhood Hits	2923	Target Neighborhood Hits	215	Shared Neighborhood Hits	110
SwissProt Accessions	Q9BXM0, Q9BXL9, Q9HCF2	Gene names	PRX, KIAA1620
Domain Architecture
Description	Periaxin.

PRAX_MOUSE
NC score	0.128351 (rank : 1161)	θ value	2.86786e-30 (rank : 133)
Query Neighborhood Hits	2923	Target Neighborhood Hits	199	Shared Neighborhood Hits	97
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

NACAM_MOUSE
NC score	0.125039 (rank : 1162)	θ value	1.86321e-21 (rank : 234)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1866	Shared Neighborhood Hits	663
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

LRRC4_MOUSE
NC score	0.124739 (rank : 1163)	θ value	5.44631e-05 (rank : 982)
Query Neighborhood Hits	2923	Target Neighborhood Hits	412	Shared Neighborhood Hits	194
SwissProt Accessions	Q99PH1, Q8VI35	Gene names	Lrrc4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing 4 protein precursor (Brain tumor- associated protein MBAG1).

OX2G_HUMAN
NC score	0.123576 (rank : 1164)	θ value	θ > 10 (rank : 3056)
Query Neighborhood Hits	2923	Target Neighborhood Hits	100	Shared Neighborhood Hits	95
SwissProt Accessions	P41217, Q6J2Q6, Q6PIQ4, Q8TB85, Q9H3J3	Gene names	CD200, MOX2
Domain Architecture
Description	OX-2 membrane glycoprotein precursor (CD200 antigen).

HCFC2_HUMAN
NC score	0.123198 (rank : 1165)	θ value	6.43352e-06 (rank : 918)
Query Neighborhood Hits	2923	Target Neighborhood Hits	154	Shared Neighborhood Hits	99
SwissProt Accessions	Q9Y5Z7	Gene names	HCFC2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

CD79A_HUMAN
NC score	0.122500 (rank : 1166)	θ value	0.0193708 (rank : 1230)
Query Neighborhood Hits	2923	Target Neighborhood Hits	102	Shared Neighborhood Hits	82
SwissProt Accessions	P11912	Gene names	CD79A, IGA, MB1
Domain Architecture
Description	B-cell antigen receptor complex-associated protein alpha-chain precursor (Ig-alpha) (MB-1 membrane glycoprotein) (Surface IgM- associated protein) (Membrane-bound immunoglobulin-associated protein) (CD79a antigen).

CT075_HUMAN
NC score	0.121274 (rank : 1167)	θ value	0.00298849 (rank : 1125)
Query Neighborhood Hits	2923	Target Neighborhood Hits	387	Shared Neighborhood Hits	159
SwissProt Accessions	Q8WUT4, Q5JWV6, Q9H419	Gene names	C20orf75
Domain Architecture
Description	Uncharacterized protein C20orf75 precursor.

SIRB1_HUMAN
NC score	0.121238 (rank : 1168)	θ value	0.000461057 (rank : 1056)
Query Neighborhood Hits	2923	Target Neighborhood Hits	422	Shared Neighborhood Hits	191
SwissProt Accessions	O00241, Q5TFR0, Q8TB12, Q9H1U5, Q9Y4V0	Gene names	SIRPB1
Domain Architecture
Description	Signal-regulatory protein beta-1 precursor (SIRP-beta-1) (CD172b antigen).

BTNL2_HUMAN
NC score	0.120658 (rank : 1169)	θ value	0.00509761 (rank : 1146)
Query Neighborhood Hits	2923	Target Neighborhood Hits	164	Shared Neighborhood Hits	144
SwissProt Accessions	Q9UIR0, O98261, Q5JYF9, Q5RIF8, Q5SP08, Q5SP09, Q5SRW3, Q5SRW4, Q5SU36, Q95HK0	Gene names	BTNL2
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 2 precursor (BTL-II).

PRPK_HUMAN
NC score	0.120039 (rank : 1170)	θ value	θ > 10 (rank : 3068)
Query Neighborhood Hits	2923	Target Neighborhood Hits	131	Shared Neighborhood Hits	123
SwissProt Accessions	Q96S44, Q3T977, Q5JZ01, Q96FM7, Q9NQE6	Gene names	TP53RK, C20orf64, PRPK
Domain Architecture
Description	TP53-regulating kinase (EC 2.7.11.1) (p53-related protein kinase) (Nori-2).

IL27B_HUMAN
NC score	0.119920 (rank : 1171)	θ value	0.00175202 (rank : 1103)
Query Neighborhood Hits	2923	Target Neighborhood Hits	80	Shared Neighborhood Hits	76
SwissProt Accessions	Q14213, O75269	Gene names	EBI3, IL27B
Domain Architecture
Description	Interleukin-27 beta chain precursor (IL-27B) (Epstein-Barr virus- induced gene 3 protein) (EBV-induced gene 3 protein).

IGSF2_HUMAN
NC score	0.118471 (rank : 1172)	θ value	0.000786445 (rank : 1074)
Query Neighborhood Hits	2923	Target Neighborhood Hits	208	Shared Neighborhood Hits	138
SwissProt Accessions	Q93033, Q15856	Gene names	IGSF2, CD101, EWI101, V7
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 2 precursor (Glu-Trp-Ile EWI motif- containing protein 101) (EWI-101) (Cell surface glycoprotein V7) (CD101 antigen).

PRPK_MOUSE
NC score	0.117758 (rank : 1173)	θ value	θ > 10 (rank : 3069)
Query Neighborhood Hits	2923	Target Neighborhood Hits	139	Shared Neighborhood Hits	129
SwissProt Accessions	Q99PW4, Q91W37, Q9CZ32	Gene names	Tp53rk, Prpk, Trp53rk
Domain Architecture
Description	TP53-regulating kinase (EC 2.7.11.1) (p53-related protein kinase) (Nori-2).

TXND2_HUMAN
NC score	0.117276 (rank : 1174)	θ value	9.87957e-23 (rank : 207)
Query Neighborhood Hits	2923	Target Neighborhood Hits	793	Shared Neighborhood Hits	378
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

RN5A_HUMAN
NC score	0.114221 (rank : 1175)	θ value	θ > 10 (rank : 3087)
Query Neighborhood Hits	2923	Target Neighborhood Hits	608	Shared Neighborhood Hits	353
SwissProt Accessions	Q05823	Gene names	RNASEL, RNS4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

ICAM1_HUMAN
NC score	0.114127 (rank : 1176)	θ value	θ > 10 (rank : 3018)
Query Neighborhood Hits	2923	Target Neighborhood Hits	80	Shared Neighborhood Hits	75
SwissProt Accessions	P05362, Q96B50	Gene names	ICAM1
Domain Architecture
Description	Intercellular adhesion molecule 1 precursor (ICAM-1) (Major group rhinovirus receptor) (CD54 antigen).

FCG3B_HUMAN
NC score	0.112842 (rank : 1177)	θ value	0.000602161 (rank : 1064)
Query Neighborhood Hits	2923	Target Neighborhood Hits	67	Shared Neighborhood Hits	66
SwissProt Accessions	O75015	Gene names	FCGR3B, CD16B, FCG3, FCGR3, IGFR3
Domain Architecture
Description	Low affinity immunoglobulin gamma Fc region receptor III-B precursor (IgG Fc receptor III-1) (Fc-gamma RIII-beta) (Fc-gamma RIIIb) (FcRIIIb) (Fc-gamma RIII) (FcRIII) (FcR-10) (CD16b antigen).

PTPRJ_HUMAN
NC score	0.112741 (rank : 1178)	θ value	2.79066e-09 (rank : 709)
Query Neighborhood Hits	2923	Target Neighborhood Hits	207	Shared Neighborhood Hits	122
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

CRLF1_HUMAN
NC score	0.111136 (rank : 1179)	θ value	0.0431538 (rank : 1283)
Query Neighborhood Hits	2923	Target Neighborhood Hits	122	Shared Neighborhood Hits	105
SwissProt Accessions	O75462, Q9UHH5	Gene names	CRLF1, ZCYTOR5
Domain Architecture
Description	Cytokine receptor-like factor 1 precursor (Cytokine-like factor 1) (CLF-1) (ZcytoR5).

FPRP_HUMAN
NC score	0.110919 (rank : 1180)	θ value	0.0961366 (rank : 1362)
Query Neighborhood Hits	2923	Target Neighborhood Hits	130	Shared Neighborhood Hits	116
SwissProt Accessions	Q9P2B2, Q8N2K6	Gene names	PTGFRN, CD9P1, FPRP, KIAA1436
Domain Architecture
Description	Prostaglandin F2 receptor negative regulator precursor (Prostaglandin F2-alpha receptor regulatory protein) (Prostaglandin F2-alpha receptor-associated protein) (CD9 partner 1) (CD9P-1) (CD315 antigen).

PRG4_MOUSE
NC score	0.110646 (rank : 1181)	θ value	0.000602161 (rank : 1068)
Query Neighborhood Hits	2923	Target Neighborhood Hits	624	Shared Neighborhood Hits	323
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

MFAP3_HUMAN
NC score	0.110176 (rank : 1182)	θ value	0.0736092 (rank : 1346)
Query Neighborhood Hits	2923	Target Neighborhood Hits	91	Shared Neighborhood Hits	89
SwissProt Accessions	P55082, Q9NXA7	Gene names	MFAP3
Domain Architecture
Description	Microfibril-associated glycoprotein 3 precursor.

ICAM3_HUMAN
NC score	0.110128 (rank : 1183)	θ value	2.36792 (rank : 2057)
Query Neighborhood Hits	2923	Target Neighborhood Hits	100	Shared Neighborhood Hits	90
SwissProt Accessions	P32942	Gene names	ICAM3
Domain Architecture
Description	Intercellular adhesion molecule 3 precursor (ICAM-3) (ICAM-R) (CDw50) (CD50 antigen).

LY9_MOUSE
NC score	0.109645 (rank : 1184)	θ value	0.00509761 (rank : 1155)
Query Neighborhood Hits	2923	Target Neighborhood Hits	110	Shared Neighborhood Hits	91
SwissProt Accessions	Q01965, Q9ES29, Q9ES35, Q9ES36	Gene names	Ly9, Ly-9
Domain Architecture
Description	T-lymphocyte surface antigen Ly-9 precursor (Lymphocyte antigen 9) (Cell-surface molecule Ly-9).

ANKF1_HUMAN
NC score	0.109243 (rank : 1185)	θ value	0.00020696 (rank : 1026)
Query Neighborhood Hits	2923	Target Neighborhood Hits	126	Shared Neighborhood Hits	60
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

PRG4_HUMAN
NC score	0.107542 (rank : 1186)	θ value	0.0148317 (rank : 1222)
Query Neighborhood Hits	2923	Target Neighborhood Hits	764	Shared Neighborhood Hits	374
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PTPRJ_MOUSE
NC score	0.107327 (rank : 1187)	θ value	4.1701e-05 (rank : 978)
Query Neighborhood Hits	2923	Target Neighborhood Hits	188	Shared Neighborhood Hits	111
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

I12R1_HUMAN
NC score	0.107278 (rank : 1188)	θ value	0.00228821 (rank : 1114)
Query Neighborhood Hits	2923	Target Neighborhood Hits	78	Shared Neighborhood Hits	68
SwissProt Accessions	P42701	Gene names	IL12RB1, IL12R, IL12RB
Domain Architecture
Description	Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) (IL- 12RB1) (CD212 antigen).

SRRM1_MOUSE
NC score	0.107266 (rank : 1189)	θ value	0.00869519 (rank : 1191)
Query Neighborhood Hits	2923	Target Neighborhood Hits	966	Shared Neighborhood Hits	416
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

PTPRV_MOUSE
NC score	0.106353 (rank : 1190)	θ value	0.00509761 (rank : 1158)
Query Neighborhood Hits	2923	Target Neighborhood Hits	179	Shared Neighborhood Hits	95
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

LAD1_MOUSE
NC score	0.105966 (rank : 1191)	θ value	2.13673e-09 (rank : 696)
Query Neighborhood Hits	2923	Target Neighborhood Hits	391	Shared Neighborhood Hits	234
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

FCGR2_MOUSE
NC score	0.105955 (rank : 1192)	θ value	0.0113563 (rank : 1200)
Query Neighborhood Hits	2923	Target Neighborhood Hits	105	Shared Neighborhood Hits	84
SwissProt Accessions	P08101, P08102, P12316, P97917, Q60938, Q60939, Q60940, Q61170, Q61558	Gene names	Fcgr2, Fcgr2b, Ly-17
Domain Architecture
Description	Low affinity immunoglobulin gamma Fc region receptor II precursor (Fc- gamma RII) (FcRII) (IgG Fc receptor II beta) (Fc gamma receptor IIB) (Fc-gamma-RIIB) (Lymphocyte antigen Ly-17) (CD32 antigen).

MFAP3_MOUSE
NC score	0.105920 (rank : 1193)	θ value	0.279714 (rank : 1513)
Query Neighborhood Hits	2923	Target Neighborhood Hits	97	Shared Neighborhood Hits	91
SwissProt Accessions	Q922T2, Q8BHK5	Gene names	Mfap3
Domain Architecture	No domain graphic available
Description	Microfibril-associated glycoprotein 3 precursor.

CRLF1_MOUSE
NC score	0.105867 (rank : 1194)	θ value	0.0330416 (rank : 1265)
Query Neighborhood Hits	2923	Target Neighborhood Hits	116	Shared Neighborhood Hits	98
SwissProt Accessions	Q9JM58	Gene names	Crlf1, Crlm3
Domain Architecture
Description	Cytokine receptor-like factor 1 precursor (Cytokine-like factor 1) (CLF-1) (Cytokine receptor-like molecule 3) (CRLM-3) (NR6).

CD4_HUMAN
NC score	0.105446 (rank : 1195)	θ value	0.163984 (rank : 1411)
Query Neighborhood Hits	2923	Target Neighborhood Hits	122	Shared Neighborhood Hits	97
SwissProt Accessions	P01730, Q4ZGK2, Q5U066	Gene names	CD4
Domain Architecture
Description	T-cell surface glycoprotein CD4 precursor (T-cell surface antigen T4/Leu-3).

PXK_HUMAN
NC score	0.105412 (rank : 1196)	θ value	θ > 10 (rank : 3077)
Query Neighborhood Hits	2923	Target Neighborhood Hits	216	Shared Neighborhood Hits	151
SwissProt Accessions	Q7Z7A4, Q3BCH4, Q3BCH5, Q3BCH6, Q3BDW1, Q45L83, Q59EX3, Q6PK17, Q6ZN39, Q96CA3, Q96R07, Q9NXB8	Gene names	PXK
Domain Architecture	No domain graphic available
Description	PX domain-containing protein kinase-like protein (Modulator of Na,K- ATPase) (MONaKA).

SIGL9_HUMAN
NC score	0.105035 (rank : 1197)	θ value	0.163984 (rank : 1433)
Query Neighborhood Hits	2923	Target Neighborhood Hits	76	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Y336, Q9BYI9	Gene names	SIGLEC9
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 9 precursor (Siglec-9) (Protein FOAP-9).

MDC1_HUMAN
NC score	0.104674 (rank : 1198)	θ value	1.80886e-08 (rank : 758)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1446	Shared Neighborhood Hits	567
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

TPSNR_MOUSE
NC score	0.104626 (rank : 1199)	θ value	0.00298849 (rank : 1133)
Query Neighborhood Hits	2923	Target Neighborhood Hits	336	Shared Neighborhood Hits	173
SwissProt Accessions	Q8VD31	Gene names	Tapbpl
Domain Architecture	No domain graphic available
Description	Tapasin-related protein precursor (TAPASIN-R) (Tapasin-like) (TAP- binding protein-related protein) (TAPBP-R) (TAP-binding protein-like).

FCG3A_HUMAN
NC score	0.104552 (rank : 1200)	θ value	0.000602161 (rank : 1063)
Query Neighborhood Hits	2923	Target Neighborhood Hits	65	Shared Neighborhood Hits	64
SwissProt Accessions	P08637	Gene names	FCGR3A, CD16A, FCG3, FCGR3, IGFR3
Domain Architecture
Description	Low affinity immunoglobulin gamma Fc region receptor III-A precursor (IgG Fc receptor III-2) (Fc-gamma RIII-alpha) (Fc-gamma RIIIa) (FcRIIIa) (Fc-gamma RIII) (FcRIII) (FcR-10) (CD16a antigen).

CD48_MOUSE
NC score	0.102960 (rank : 1201)	θ value	0.47712 (rank : 1594)
Query Neighborhood Hits	2923	Target Neighborhood Hits	96	Shared Neighborhood Hits	80
SwissProt Accessions	P18181, Q545K2	Gene names	Cd48, Bcm-1
Domain Architecture
Description	CD48 antigen precursor (MRC OX-45 surface antigen) (BCM1 surface antigen) (BLAST-1) (HM48-1) (sgp-60).

SHPS1_MOUSE
NC score	0.101177 (rank : 1202)	θ value	0.00175202 (rank : 1108)
Query Neighborhood Hits	2923	Target Neighborhood Hits	439	Shared Neighborhood Hits	197
SwissProt Accessions	P97797, O08907, O35924, O88555, O88556, P97796, Q8R559, Q9QX57, Q9WTN4	Gene names	Sirpa, Bit, Myd1, Ptpns1, Shps1, Sirp
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type substrate 1 precursor (SHP substrate 1) (SHPS-1) (Inhibitory receptor SHPS-1) (Signal- regulatory protein alpha-1) (Sirp-alpha-1) (mSIRP-alpha1) (MyD-1 antigen) (Brain Ig-like molecule with tyrosine-based activation motifs) (Bit) (p84) (CD172a antigen).

FPRP_MOUSE
NC score	0.101173 (rank : 1203)	θ value	0.00665767 (rank : 1164)
Query Neighborhood Hits	2923	Target Neighborhood Hits	116	Shared Neighborhood Hits	95
SwissProt Accessions	Q9WV91	Gene names	Ptgfrn, Fprp
Domain Architecture
Description	Prostaglandin F2 receptor negative regulator precursor (Prostaglandin F2-alpha receptor regulatory protein) (Prostaglandin F2-alpha receptor-associated protein) (CD315 antigen).

MOX2R_HUMAN
NC score	0.099743 (rank : 1204)	θ value	0.47712 (rank : 1616)
Query Neighborhood Hits	2923	Target Neighborhood Hits	51	Shared Neighborhood Hits	51
SwissProt Accessions	Q8TD46, Q8TD44, Q8TD45, Q8TD52	Gene names	CD200R1, CD200R, CRTR2, MOX2R, OX2R
Domain Architecture	No domain graphic available
Description	Cell surface glycoprotein OX2 receptor precursor (CD200 cell surface glycoprotein receptor).

CN155_HUMAN
NC score	0.099475 (rank : 1205)	θ value	0.365318 (rank : 1541)
Query Neighborhood Hits	2923	Target Neighborhood Hits	385	Shared Neighborhood Hits	229
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

LAD1_HUMAN
NC score	0.099029 (rank : 1206)	θ value	6.87365e-08 (rank : 785)
Query Neighborhood Hits	2923	Target Neighborhood Hits	441	Shared Neighborhood Hits	218
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

BUB1B_HUMAN
NC score	0.098844 (rank : 1207)	θ value	4.03905 (rank : 2259)
Query Neighborhood Hits	2923	Target Neighborhood Hits	208	Shared Neighborhood Hits	159
SwissProt Accessions	O60566, O60501, O60627, O60758, O75389, Q96KM4	Gene names	BUB1B, BUBR1, MAD3L
Domain Architecture
Description	Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (hBUBR1) (MAD3/BUB1-related protein kinase) (Mitotic checkpoint kinase MAD3L) (SSK1).

I11RB_MOUSE
NC score	0.098396 (rank : 1208)	θ value	0.279714 (rank : 1506)
Query Neighborhood Hits	2923	Target Neighborhood Hits	101	Shared Neighborhood Hits	85
SwissProt Accessions	P70225, O09074, Q78DW8	Gene names	Il11ra2
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha-2 chain precursor (IL-11R-alpha-2) (Interleukin-11 receptor beta chain) (IL-11R-beta).

RIMB2_HUMAN
NC score	0.098319 (rank : 1209)	θ value	0.0736092 (rank : 1350)
Query Neighborhood Hits	2923	Target Neighborhood Hits	263	Shared Neighborhood Hits	120
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

SIRPG_HUMAN
NC score	0.097321 (rank : 1210)	θ value	0.0113563 (rank : 1208)
Query Neighborhood Hits	2923	Target Neighborhood Hits	359	Shared Neighborhood Hits	153
SwissProt Accessions	Q9P1W8, Q8WWA5, Q9NQK8	Gene names	SIRPG, SIRPB2
Domain Architecture
Description	Signal-regulatory protein gamma precursor (Signal-regulatory protein beta-2) (SIRP-beta-2) (SIRP-b2) (CD172g antigen).

TPSNR_HUMAN
NC score	0.097216 (rank : 1211)	θ value	0.365318 (rank : 1573)
Query Neighborhood Hits	2923	Target Neighborhood Hits	330	Shared Neighborhood Hits	161
SwissProt Accessions	Q9BX59, Q9NWB8	Gene names	TAPBPL
Domain Architecture	No domain graphic available
Description	Tapasin-related protein precursor (TAPASIN-R) (Tapasin-like) (TAP- binding protein-related protein) (TAPBP-R) (TAP-binding protein-like).

MAP4_HUMAN
NC score	0.097127 (rank : 1212)	θ value	2.43908e-13 (rank : 490)
Query Neighborhood Hits	2923	Target Neighborhood Hits	428	Shared Neighborhood Hits	221
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

CT075_MOUSE
NC score	0.096912 (rank : 1213)	θ value	0.0113563 (rank : 1197)
Query Neighborhood Hits	2923	Target Neighborhood Hits	358	Shared Neighborhood Hits	137
SwissProt Accessions	P59383	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf75 homolog precursor.

BT3A2_HUMAN
NC score	0.096845 (rank : 1214)	θ value	0.0193708 (rank : 1228)
Query Neighborhood Hits	2923	Target Neighborhood Hits	158	Shared Neighborhood Hits	134
SwissProt Accessions	P78410, O00477, O15338, O75658, Q76PA0, Q9BU81, Q9NR44	Gene names	BTN3A2, BT3.2, BTF3, BTF4
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A2 precursor.

PCLO_HUMAN
NC score	0.096692 (rank : 1215)	θ value	2.61198e-07 (rank : 837)
Query Neighborhood Hits	2923	Target Neighborhood Hits	2046	Shared Neighborhood Hits	766
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

MAP1A_HUMAN
NC score	0.096524 (rank : 1216)	θ value	1.09739e-05 (rank : 936)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1626	Shared Neighborhood Hits	667
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

SRRM2_MOUSE
NC score	0.096375 (rank : 1217)	θ value	5.27518 (rank : 2520)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1470	Shared Neighborhood Hits	537
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

SRRM1_HUMAN
NC score	0.096367 (rank : 1218)	θ value	0.813845 (rank : 1747)
Query Neighborhood Hits	2923	Target Neighborhood Hits	690	Shared Neighborhood Hits	323
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

CD244_HUMAN
NC score	0.095425 (rank : 1219)	θ value	5.44631e-05 (rank : 980)
Query Neighborhood Hits	2923	Target Neighborhood Hits	72	Shared Neighborhood Hits	56
SwissProt Accessions	Q9BZW8, Q96T47, Q9NQD2, Q9NQD3, Q9Y288	Gene names	CD244, 2B4
Domain Architecture
Description	Natural killer cell receptor 2B4 precursor (NKR2B4) (NK cell type I receptor protein 2B4) (h2B4) (CD244 antigen) (NK cell activation- inducing ligand) (NAIL).

SRRM2_HUMAN
NC score	0.094786 (rank : 1220)	θ value	1.38821 (rank : 1891)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1296	Shared Neighborhood Hits	509
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

FCERA_MOUSE
NC score	0.094238 (rank : 1221)	θ value	0.62314 (rank : 1664)
Query Neighborhood Hits	2923	Target Neighborhood Hits	54	Shared Neighborhood Hits	50
SwissProt Accessions	P20489	Gene names	Fcer1a, Fce1a
Domain Architecture
Description	High affinity immunoglobulin epsilon receptor alpha-subunit precursor (FcERI) (IgE Fc receptor, alpha-subunit) (Fc-epsilon RI-alpha).

RIMB2_MOUSE
NC score	0.094109 (rank : 1222)	θ value	0.00175202 (rank : 1107)
Query Neighborhood Hits	2923	Target Neighborhood Hits	246	Shared Neighborhood Hits	115
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

I11RA_MOUSE
NC score	0.094102 (rank : 1223)	θ value	0.365318 (rank : 1552)
Query Neighborhood Hits	2923	Target Neighborhood Hits	95	Shared Neighborhood Hits	81
SwissProt Accessions	Q64385, Q6NSQ0	Gene names	Il11ra1, Etl2, Il11ra
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha-1 chain precursor (IL-11R-alpha-1) (IL- 11RA1) (IL-11R-alpha) (IL-11RA) (Enhancer trap locus homolog 2) (Etl- 2) (NR-1).

MDC1_MOUSE
NC score	0.093819 (rank : 1224)	θ value	1.38499e-08 (rank : 748)
Query Neighborhood Hits	2923	Target Neighborhood Hits	998	Shared Neighborhood Hits	424
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

FCGR3_MOUSE
NC score	0.093186 (rank : 1225)	θ value	0.21417 (rank : 1459)
Query Neighborhood Hits	2923	Target Neighborhood Hits	98	Shared Neighborhood Hits	75
SwissProt Accessions	P08508	Gene names	Fcgr3
Domain Architecture
Description	Low affinity immunoglobulin gamma Fc region receptor III precursor (IgG Fc receptor III) (Fc-gamma RIII) (FcRIII).

TRDN_HUMAN
NC score	0.093154 (rank : 1226)	θ value	0.000461057 (rank : 1059)
Query Neighborhood Hits	2923	Target Neighborhood Hits	542	Shared Neighborhood Hits	306
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

I11RA_HUMAN
NC score	0.092828 (rank : 1227)	θ value	0.0736092 (rank : 1336)
Query Neighborhood Hits	2923	Target Neighborhood Hits	138	Shared Neighborhood Hits	102
SwissProt Accessions	Q14626, Q16542, Q7KYJ7	Gene names	IL11RA
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha chain precursor (IL-11R-alpha) (IL- 11RA).

MAP1B_HUMAN
NC score	0.092441 (rank : 1228)	θ value	0.00175202 (rank : 1105)
Query Neighborhood Hits	2923	Target Neighborhood Hits	903	Shared Neighborhood Hits	433
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

ICOSL_MOUSE
NC score	0.091514 (rank : 1229)	θ value	0.21417 (rank : 1468)
Query Neighborhood Hits	2923	Target Neighborhood Hits	93	Shared Neighborhood Hits	82
SwissProt Accessions	Q9JHJ8	Gene names	Icoslg, B7h2, B7rp1, Icosl
Domain Architecture
Description	ICOS ligand precursor (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (LICOS) (CD275 antigen).

I12R1_MOUSE
NC score	0.091146 (rank : 1230)	θ value	0.0563607 (rank : 1313)
Query Neighborhood Hits	2923	Target Neighborhood Hits	70	Shared Neighborhood Hits	57
SwissProt Accessions	Q60837	Gene names	Il12rb1, Il12rb
Domain Architecture
Description	Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) (CD212 antigen).

HCFC1_MOUSE
NC score	0.090525 (rank : 1231)	θ value	0.00134147 (rank : 1093)
Query Neighborhood Hits	2923	Target Neighborhood Hits	348	Shared Neighborhood Hits	172
SwissProt Accessions	Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2	Gene names	Hcfc1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

SON_HUMAN
NC score	0.090350 (rank : 1232)	θ value	4.16044e-13 (rank : 495)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1568	Shared Neighborhood Hits	531
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

ACINU_HUMAN
NC score	0.090298 (rank : 1233)	θ value	0.000121331 (rank : 1008)
Query Neighborhood Hits	2923	Target Neighborhood Hits	828	Shared Neighborhood Hits	417
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

SON_MOUSE
NC score	0.089915 (rank : 1234)	θ value	5.26297e-08 (rank : 779)
Query Neighborhood Hits	2923	Target Neighborhood Hits	957	Shared Neighborhood Hits	377
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

PCLO_MOUSE
NC score	0.089627 (rank : 1235)	θ value	0.00228821 (rank : 1121)
Query Neighborhood Hits	2923	Target Neighborhood Hits	2275	Shared Neighborhood Hits	786
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

JAML1_HUMAN
NC score	0.088908 (rank : 1236)	θ value	3.0926 (rank : 2177)
Query Neighborhood Hits	2923	Target Neighborhood Hits	108	Shared Neighborhood Hits	90
SwissProt Accessions	Q86YT9, Q5DTC6, Q7Z499, Q8N9I7, Q8NF70	Gene names	AMICA1, JAML
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule-like precursor (Dendritic cell-specific protein CREA7-1) (Adhesion molecule interacting with CXADR antigen 1).

IL6RA_MOUSE
NC score	0.088835 (rank : 1237)	θ value	θ > 10 (rank : 3025)
Query Neighborhood Hits	2923	Target Neighborhood Hits	104	Shared Neighborhood Hits	97
SwissProt Accessions	P22272	Gene names	Il6ra, Il6r
Domain Architecture
Description	Interleukin-6 receptor alpha chain precursor (IL-6R-alpha) (IL-6R 1) (CD126 antigen).

SIGIR_MOUSE
NC score	0.088768 (rank : 1238)	θ value	0.125558 (rank : 1400)
Query Neighborhood Hits	2923	Target Neighborhood Hits	95	Shared Neighborhood Hits	71
SwissProt Accessions	Q9JLZ8, Q52L48	Gene names	Sigirr, Tir8
Domain Architecture	No domain graphic available
Description	Single Ig IL-1-related receptor (Single Ig IL-1R-related molecule) (Single immunoglobulin domain-containing IL1R-related protein) (Toll/interleukin-1 receptor 8) (TIR8).

NOLC1_HUMAN
NC score	0.088744 (rank : 1239)	θ value	0.0563607 (rank : 1323)
Query Neighborhood Hits	2923	Target Neighborhood Hits	452	Shared Neighborhood Hits	218
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

I18RA_MOUSE
NC score	0.088569 (rank : 1240)	θ value	0.00509761 (rank : 1148)
Query Neighborhood Hits	2923	Target Neighborhood Hits	93	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Z2B1	Gene names	Il18rap
Domain Architecture	No domain graphic available
Description	Interleukin-18 receptor accessory protein precursor (IL-18 receptor accessory protein) (IL-18RAcP) (Interleukin-18 receptor accessory protein-like) (IL-18Rbeta) (IL-1R accessory protein-like) (IL-1RAcPL) (Accessory protein-like) (AcPL) (IL-1R7).

IL1AP_MOUSE
NC score	0.088370 (rank : 1241)	θ value	9.29e-05 (rank : 999)
Query Neighborhood Hits	2923	Target Neighborhood Hits	94	Shared Neighborhood Hits	67
SwissProt Accessions	Q61730, Q8VCB9	Gene names	Il1rap
Domain Architecture
Description	Interleukin-1 receptor accessory protein precursor (IL-1 receptor accessory protein) (IL-1RAcP).

CD226_HUMAN
NC score	0.087453 (rank : 1242)	θ value	0.47712 (rank : 1593)
Query Neighborhood Hits	2923	Target Neighborhood Hits	87	Shared Neighborhood Hits	79
SwissProt Accessions	Q15762	Gene names	CD226, DNAM1
Domain Architecture
Description	CD226 antigen precursor (DNAX accessory molecule 1) (DNAM-1).

I18RA_HUMAN
NC score	0.087232 (rank : 1243)	θ value	0.0431538 (rank : 1287)
Query Neighborhood Hits	2923	Target Neighborhood Hits	97	Shared Neighborhood Hits	72
SwissProt Accessions	O95256, Q53TT4, Q53TU5	Gene names	IL18RAP
Domain Architecture	No domain graphic available
Description	Interleukin-18 receptor accessory protein precursor (IL-18 receptor accessory protein) (IL-18RAcP) (Interleukin-18 receptor accessory protein-like) (IL-18Rbeta) (IL-1R accessory protein-like) (IL-1RAcPL) (Accessory protein-like) (AcPL) (IL-1R7) (CDw218b antigen).

TMM25_MOUSE
NC score	0.086993 (rank : 1244)	θ value	0.0113563 (rank : 1209)
Query Neighborhood Hits	2923	Target Neighborhood Hits	46	Shared Neighborhood Hits	45
SwissProt Accessions	Q9DCF1, Q3TMP3, Q6PAK7	Gene names	Tmem25
Domain Architecture	No domain graphic available
Description	Transmembrane protein 25 precursor.

TMM25_HUMAN
NC score	0.086751 (rank : 1245)	θ value	0.00175202 (rank : 1110)
Query Neighborhood Hits	2923	Target Neighborhood Hits	43	Shared Neighborhood Hits	41
SwissProt Accessions	Q86YD3, Q6UW89, Q86UA7, Q96KA6, Q96MW9	Gene names	TMEM25
Domain Architecture	No domain graphic available
Description	Transmembrane protein 25 precursor.

BTNL1_MOUSE
NC score	0.086299 (rank : 1246)	θ value	0.125558 (rank : 1385)
Query Neighborhood Hits	2923	Target Neighborhood Hits	151	Shared Neighborhood Hits	124
SwissProt Accessions	Q7TST0, O70356	Gene names	Btnl1, Btnl3, Gm316, Ng10
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 1 precursor.

MAP1B_MOUSE
NC score	0.085360 (rank : 1247)	θ value	0.00869519 (rank : 1182)
Query Neighborhood Hits	2923	Target Neighborhood Hits	977	Shared Neighborhood Hits	449
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

BASP_MOUSE
NC score	0.084839 (rank : 1248)	θ value	1.38821 (rank : 1822)
Query Neighborhood Hits	2923	Target Neighborhood Hits	260	Shared Neighborhood Hits	145
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

NFH_MOUSE
NC score	0.084725 (rank : 1249)	θ value	2.0648e-12 (rank : 528)
Query Neighborhood Hits	2923	Target Neighborhood Hits	2247	Shared Neighborhood Hits	814
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

CEAMA_MOUSE
NC score	0.084301 (rank : 1250)	θ value	θ > 10 (rank : 2969)
Query Neighborhood Hits	2923	Target Neighborhood Hits	41	Shared Neighborhood Hits	37
SwissProt Accessions	Q61400, Q99LD6, Q9D329	Gene names	Ceacam10, Cea10
Domain Architecture	No domain graphic available
Description	Carcinoembryonic antigen-related cell adhesion molecule 10 precursor (CEA-related cell adhesion molecule 10) (Carcinoembryonic antigen 10) (CEA10).

CEAM3_HUMAN
NC score	0.084292 (rank : 1251)	θ value	θ > 10 (rank : 2968)
Query Neighborhood Hits	2923	Target Neighborhood Hits	28	Shared Neighborhood Hits	23
SwissProt Accessions	P40198	Gene names	CEACAM3, CD66D, CGM1
Domain Architecture	No domain graphic available
Description	Carcinoembryonic antigen-related cell adhesion molecule 3 precursor (Carcinoembryonic antigen CGM1) (CD66d antigen).

CD48_HUMAN
NC score	0.084112 (rank : 1252)	θ value	0.62314 (rank : 1655)
Query Neighborhood Hits	2923	Target Neighborhood Hits	64	Shared Neighborhood Hits	55
SwissProt Accessions	P09326	Gene names	CD48, BCM1, BLAST1
Domain Architecture	No domain graphic available
Description	CD48 antigen precursor (B-lymphocyte activation marker BLAST-1) (BCM1 surface antigen) (Leukocyte antigen MEM-102) (TCT.1).

RIMB1_HUMAN
NC score	0.083262 (rank : 1253)	θ value	2.36792 (rank : 2096)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1479	Shared Neighborhood Hits	551
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

IL6RA_HUMAN
NC score	0.082994 (rank : 1254)	θ value	0.00869519 (rank : 1179)
Query Neighborhood Hits	2923	Target Neighborhood Hits	96	Shared Neighborhood Hits	82
SwissProt Accessions	P08887, Q16202, Q53EQ7, Q5FWG2, Q5VZ23	Gene names	IL6R
Domain Architecture
Description	Interleukin-6 receptor alpha chain precursor (IL-6R-alpha) (IL-6R 1) (Membrane glycoprotein 80) (gp80) (CD126 antigen).

PTPRO_HUMAN
NC score	0.082865 (rank : 1255)	θ value	0.0113563 (rank : 1207)
Query Neighborhood Hits	2923	Target Neighborhood Hits	139	Shared Neighborhood Hits	75
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

MAP4_MOUSE
NC score	0.082120 (rank : 1256)	θ value	0.00509761 (rank : 1156)
Query Neighborhood Hits	2923	Target Neighborhood Hits	409	Shared Neighborhood Hits	204
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

CALD1_HUMAN
NC score	0.081353 (rank : 1257)	θ value	0.00020696 (rank : 1027)
Query Neighborhood Hits	2923	Target Neighborhood Hits	959	Shared Neighborhood Hits	417
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

I27RA_HUMAN
NC score	0.081024 (rank : 1258)	θ value	0.365318 (rank : 1553)
Query Neighborhood Hits	2923	Target Neighborhood Hits	60	Shared Neighborhood Hits	50
SwissProt Accessions	Q6UWB1, O60624	Gene names	IL27RA, CRL1, TCCR, WSX1
Domain Architecture	No domain graphic available
Description	Interleukin-27 receptor alpha chain precursor (IL-27R-alpha) (WSX-1) (Type I T-cell cytokine receptor) (TCCR) (Protein CRL1).

BT1A1_MOUSE
NC score	0.080927 (rank : 1259)	θ value	0.000602161 (rank : 1061)
Query Neighborhood Hits	2923	Target Neighborhood Hits	252	Shared Neighborhood Hits	170
SwissProt Accessions	Q62556, P97392, Q8K2H7, Q921K7	Gene names	Btn1a1, Btn
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BASP_HUMAN
NC score	0.080636 (rank : 1260)	θ value	θ > 10 (rank : 2949)
Query Neighborhood Hits	2923	Target Neighborhood Hits	321	Shared Neighborhood Hits	160
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BSN_MOUSE
NC score	0.080492 (rank : 1261)	θ value	0.62314 (rank : 1653)
Query Neighborhood Hits	2923	Target Neighborhood Hits	2057	Shared Neighborhood Hits	691
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

A1BG_HUMAN
NC score	0.080419 (rank : 1262)	θ value	0.47712 (rank : 1581)
Query Neighborhood Hits	2923	Target Neighborhood Hits	94	Shared Neighborhood Hits	66
SwissProt Accessions	P04217, Q8IYJ6, Q96P39	Gene names	A1BG
Domain Architecture
Description	Alpha-1B-glycoprotein precursor (Alpha-1-B glycoprotein).

GRP3_HUMAN
NC score	0.080110 (rank : 1263)	θ value	θ > 10 (rank : 3009)
Query Neighborhood Hits	2923	Target Neighborhood Hits	131	Shared Neighborhood Hits	48
SwissProt Accessions	Q8IV61, O94931	Gene names	RASGRP3, GRP3, KIAA0846
Domain Architecture
Description	RAS guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1).

AMGO2_HUMAN
NC score	0.080078 (rank : 1264)	θ value	1.81305 (rank : 1905)
Query Neighborhood Hits	2923	Target Neighborhood Hits	357	Shared Neighborhood Hits	153
SwissProt Accessions	Q86SJ2, Q7Z4A0, Q96CN8	Gene names	AMIGO2, ALI1
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 2 precursor (AMIGO-2) (Alivin-1) (Differentially expressed in gastric adenocarcinomas) (DEGA).

PRP1_HUMAN
NC score	0.079639 (rank : 1265)	θ value	1.81305 (rank : 1970)
Query Neighborhood Hits	2923	Target Neighborhood Hits	385	Shared Neighborhood Hits	190
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

TXND2_MOUSE
NC score	0.079448 (rank : 1266)	θ value	3.29651e-10 (rank : 648)
Query Neighborhood Hits	2923	Target Neighborhood Hits	828	Shared Neighborhood Hits	348
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

HCFC1_HUMAN
NC score	0.079141 (rank : 1267)	θ value	0.00665767 (rank : 1165)
Query Neighborhood Hits	2923	Target Neighborhood Hits	331	Shared Neighborhood Hits	155
SwissProt Accessions	P51610, Q6P4G5	Gene names	HCFC1, HCF1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) (VP16 accessory protein) (VCAF) (CFF) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C- terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

SLAP2_MOUSE
NC score	0.078842 (rank : 1268)	θ value	θ > 10 (rank : 3097)
Query Neighborhood Hits	2923	Target Neighborhood Hits	136	Shared Neighborhood Hits	47
SwissProt Accessions	Q8R4L0, Q3UU74, Q8C0K2, Q8VI42, Q9D1Z9	Gene names	Sla2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2).

BSN_HUMAN
NC score	0.078492 (rank : 1269)	θ value	5.27518 (rank : 2392)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1537	Shared Neighborhood Hits	603
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

RP1L1_HUMAN
NC score	0.078046 (rank : 1270)	θ value	0.62314 (rank : 1687)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1072	Shared Neighborhood Hits	406
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

MUC7_HUMAN
NC score	0.077637 (rank : 1271)	θ value	θ > 10 (rank : 3047)
Query Neighborhood Hits	2923	Target Neighborhood Hits	538	Shared Neighborhood Hits	265
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

MINT_HUMAN
NC score	0.077493 (rank : 1272)	θ value	0.00869519 (rank : 1183)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1291	Shared Neighborhood Hits	521
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

CCD11_HUMAN
NC score	0.077382 (rank : 1273)	θ value	0.0563607 (rank : 1304)
Query Neighborhood Hits	2923	Target Neighborhood Hits	822	Shared Neighborhood Hits	382
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

TARA_HUMAN
NC score	0.077341 (rank : 1274)	θ value	0.47712 (rank : 1638)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1626	Shared Neighborhood Hits	619
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

IL1AP_HUMAN
NC score	0.076686 (rank : 1275)	θ value	0.00102713 (rank : 1081)
Query Neighborhood Hits	2923	Target Neighborhood Hits	85	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NPH3, O14915, Q86WJ7	Gene names	IL1RAP
Domain Architecture
Description	Interleukin-1 receptor accessory protein precursor (IL-1 receptor accessory protein) (IL-1RAcP).

SLAP2_HUMAN
NC score	0.076195 (rank : 1276)	θ value	θ > 10 (rank : 3096)
Query Neighborhood Hits	2923	Target Neighborhood Hits	139	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H6Q3, Q5TH27, Q5TH28, Q8WY18, Q96QI4, Q9H135	Gene names	SLA2, C20orf156, SLAP2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2) (Modulator of antigen receptor signaling) (MARS).

RIMB1_MOUSE
NC score	0.075783 (rank : 1277)	θ value	4.03905 (rank : 2343)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1376	Shared Neighborhood Hits	531
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

BUB1B_MOUSE
NC score	0.075382 (rank : 1278)	θ value	8.99809 (rank : 2739)
Query Neighborhood Hits	2923	Target Neighborhood Hits	202	Shared Neighborhood Hits	160
SwissProt Accessions	Q9Z1S0	Gene names	Bub1b, Mad3l
Domain Architecture
Description	Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (MAD3/BUB1-related protein kinase) (Mitotic checkpoint kinase MAD3L).

ACINU_MOUSE
NC score	0.075296 (rank : 1279)	θ value	0.47712 (rank : 1582)
Query Neighborhood Hits	2923	Target Neighborhood Hits	712	Shared Neighborhood Hits	375
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

SLAP1_HUMAN
NC score	0.075020 (rank : 1280)	θ value	θ > 10 (rank : 3094)
Query Neighborhood Hits	2923	Target Neighborhood Hits	113	Shared Neighborhood Hits	43
SwissProt Accessions	Q13239, Q9UMQ8	Gene names	SLA, SLAP, SLAP1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (hSLAP).

LY9_HUMAN
NC score	0.074877 (rank : 1281)	θ value	0.00869519 (rank : 1181)
Query Neighborhood Hits	2923	Target Neighborhood Hits	82	Shared Neighborhood Hits	65
SwissProt Accessions	Q9HBG7, Q14775, Q5VYI3, Q9H4N5, Q9NQ24	Gene names	LY9
Domain Architecture
Description	T-lymphocyte surface antigen Ly-9 precursor (Lymphocyte antigen 9) (Cell-surface molecule Ly-9) (CD229 antigen).

INCE_HUMAN
NC score	0.074862 (rank : 1282)	θ value	0.62314 (rank : 1672)
Query Neighborhood Hits	2923	Target Neighborhood Hits	978	Shared Neighborhood Hits	425
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

TCRG1_MOUSE
NC score	0.074286 (rank : 1283)	θ value	0.47712 (rank : 1641)
Query Neighborhood Hits	2923	Target Neighborhood Hits	947	Shared Neighborhood Hits	470
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

LR37A_HUMAN
NC score	0.074096 (rank : 1284)	θ value	0.00102713 (rank : 1083)
Query Neighborhood Hits	2923	Target Neighborhood Hits	720	Shared Neighborhood Hits	286
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

SLAF5_MOUSE
NC score	0.074065 (rank : 1285)	θ value	3.19293e-05 (rank : 968)
Query Neighborhood Hits	2923	Target Neighborhood Hits	93	Shared Neighborhood Hits	77
SwissProt Accessions	Q18PI6, Q18PI7, Q3TBT1, Q3U0A2, Q8BFV0, Q9Z178	Gene names	Cd84, Slamf5
Domain Architecture	No domain graphic available
Description	SLAM family member 5 precursor (Signaling lymphocytic activation molecule 5) (Leukocyte differentiation antigen CD84) (CD84 antigen).

SLAP1_MOUSE
NC score	0.073989 (rank : 1286)	θ value	θ > 10 (rank : 3095)
Query Neighborhood Hits	2923	Target Neighborhood Hits	117	Shared Neighborhood Hits	46
SwissProt Accessions	Q60898, Q8C9Q8, Q8CAT0, Q8CBE9, Q8QZX8	Gene names	Sla, Slap, Slap1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (mSLAP).

INCE_MOUSE
NC score	0.073916 (rank : 1287)	θ value	0.0431538 (rank : 1288)
Query Neighborhood Hits	2923	Target Neighborhood Hits	903	Shared Neighborhood Hits	398
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

GP116_HUMAN
NC score	0.073527 (rank : 1288)	θ value	6.87365e-08 (rank : 783)
Query Neighborhood Hits	2923	Target Neighborhood Hits	167	Shared Neighborhood Hits	89
SwissProt Accessions	Q8IZF2, O94858, Q6RGN2, Q86SP0, Q9Y3Z2	Gene names	GPR116, KIAA0758
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 116 precursor.

MADCA_HUMAN
NC score	0.073229 (rank : 1289)	θ value	θ > 10 (rank : 3037)
Query Neighborhood Hits	2923	Target Neighborhood Hits	221	Shared Neighborhood Hits	132
SwissProt Accessions	Q13477, O60222, O75867	Gene names	MADCAM1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (hMAdCAM-1).

PRB4S_HUMAN
NC score	0.073170 (rank : 1290)	θ value	6.88961 (rank : 2674)
Query Neighborhood Hits	2923	Target Neighborhood Hits	330	Shared Neighborhood Hits	161
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

CD33_HUMAN
NC score	0.073069 (rank : 1291)	θ value	θ > 10 (rank : 2966)
Query Neighborhood Hits	2923	Target Neighborhood Hits	50	Shared Neighborhood Hits	44
SwissProt Accessions	P20138, Q8TD24	Gene names	CD33
Domain Architecture
Description	Myeloid cell surface antigen CD33 precursor (Siglec-3) (gp67).

LEPR_HUMAN
NC score	0.072913 (rank : 1292)	θ value	0.0431538 (rank : 1289)
Query Neighborhood Hits	2923	Target Neighborhood Hits	112	Shared Neighborhood Hits	86
SwissProt Accessions	P48357, Q13592, Q13593, Q13594, Q92919, Q92920, Q92921	Gene names	LEPR, DB, OBR
Domain Architecture
Description	Leptin receptor precursor (LEP-R) (OB receptor) (OB-R) (HuB219) (CD295 antigen).

MINT_MOUSE
NC score	0.072825 (rank : 1293)	θ value	0.00102713 (rank : 1084)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1514	Shared Neighborhood Hits	572
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

BT1A1_HUMAN
NC score	0.072624 (rank : 1294)	θ value	0.0252991 (rank : 1251)
Query Neighborhood Hits	2923	Target Neighborhood Hits	322	Shared Neighborhood Hits	161
SwissProt Accessions	Q13410, Q9H458	Gene names	BTN1A1, BTN
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

INVO_HUMAN
NC score	0.072311 (rank : 1295)	θ value	θ > 10 (rank : 3026)
Query Neighborhood Hits	2923	Target Neighborhood Hits	636	Shared Neighborhood Hits	311
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

TCRG1_HUMAN
NC score	0.072306 (rank : 1296)	θ value	4.03905 (rank : 2361)
Query Neighborhood Hits	2923	Target Neighborhood Hits	929	Shared Neighborhood Hits	458
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

PRRT3_HUMAN
NC score	0.071844 (rank : 1297)	θ value	9.59137e-10 (rank : 667)
Query Neighborhood Hits	2923	Target Neighborhood Hits	998	Shared Neighborhood Hits	335
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

TACC2_HUMAN
NC score	0.071807 (rank : 1298)	θ value	0.00228821 (rank : 1124)
Query Neighborhood Hits	2923	Target Neighborhood Hits	856	Shared Neighborhood Hits	417
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

NFH_HUMAN
NC score	0.071604 (rank : 1299)	θ value	4.76016e-09 (rank : 722)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1242	Shared Neighborhood Hits	592
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PININ_HUMAN
NC score	0.071367 (rank : 1300)	θ value	θ > 10 (rank : 3063)
Query Neighborhood Hits	2923	Target Neighborhood Hits	753	Shared Neighborhood Hits	382
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

PRP2_MOUSE
NC score	0.071262 (rank : 1301)	θ value	θ > 10 (rank : 3067)
Query Neighborhood Hits	2923	Target Neighborhood Hits	347	Shared Neighborhood Hits	164
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

KI67_HUMAN
NC score	0.071044 (rank : 1302)	θ value	0.0113563 (rank : 1203)
Query Neighborhood Hits	2923	Target Neighborhood Hits	581	Shared Neighborhood Hits	282
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

IL18R_MOUSE
NC score	0.070952 (rank : 1303)	θ value	0.00509761 (rank : 1151)
Query Neighborhood Hits	2923	Target Neighborhood Hits	82	Shared Neighborhood Hits	50
SwissProt Accessions	Q61098	Gene names	Il18r1
Domain Architecture
Description	Interleukin-18 receptor 1 precursor (IL1 receptor-related protein) (IL-1Rrp).

ZC313_HUMAN
NC score	0.070759 (rank : 1304)	θ value	0.279714 (rank : 1529)
Query Neighborhood Hits	2923	Target Neighborhood Hits	772	Shared Neighborhood Hits	338
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

TRHY_HUMAN
NC score	0.070756 (rank : 1305)	θ value	0.813845 (rank : 1756)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1385	Shared Neighborhood Hits	494
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

PDZD8_HUMAN
NC score	0.070627 (rank : 1306)	θ value	θ > 10 (rank : 3061)
Query Neighborhood Hits	2923	Target Neighborhood Hits	185	Shared Neighborhood Hits	86
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

STAC_MOUSE
NC score	0.070602 (rank : 1307)	θ value	θ > 10 (rank : 3104)
Query Neighborhood Hits	2923	Target Neighborhood Hits	268	Shared Neighborhood Hits	102
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

TGON2_HUMAN
NC score	0.069826 (rank : 1308)	θ value	0.00298849 (rank : 1132)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1037	Shared Neighborhood Hits	351
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

CJ078_MOUSE
NC score	0.069650 (rank : 1309)	θ value	8.99809 (rank : 2754)
Query Neighborhood Hits	2923	Target Neighborhood Hits	559	Shared Neighborhood Hits	278
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

UN13A_HUMAN
NC score	0.069610 (rank : 1310)	θ value	4.03905 (rank : 2365)
Query Neighborhood Hits	2923	Target Neighborhood Hits	285	Shared Neighborhood Hits	98
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

PRR12_HUMAN
NC score	0.069573 (rank : 1311)	θ value	θ > 10 (rank : 3070)
Query Neighborhood Hits	2923	Target Neighborhood Hits	460	Shared Neighborhood Hits	224
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

MLL2_HUMAN
NC score	0.069025 (rank : 1312)	θ value	1.06291 (rank : 1794)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1788	Shared Neighborhood Hits	644
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

INVO_MOUSE
NC score	0.068949 (rank : 1313)	θ value	θ > 10 (rank : 3027)
Query Neighborhood Hits	2923	Target Neighborhood Hits	474	Shared Neighborhood Hits	260
SwissProt Accessions	P48997	Gene names	Ivl
Domain Architecture	No domain graphic available
Description	Involucrin.

STAC3_MOUSE
NC score	0.068895 (rank : 1314)	θ value	θ > 10 (rank : 3102)
Query Neighborhood Hits	2923	Target Neighborhood Hits	232	Shared Neighborhood Hits	81
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

CD33_MOUSE
NC score	0.068864 (rank : 1315)	θ value	8.99809 (rank : 2745)
Query Neighborhood Hits	2923	Target Neighborhood Hits	45	Shared Neighborhood Hits	36
SwissProt Accessions	Q63994, Q63997	Gene names	Cd33
Domain Architecture
Description	Myeloid cell surface antigen CD33 precursor (Siglec-3).

CCD91_HUMAN
NC score	0.068750 (rank : 1316)	θ value	0.163984 (rank : 1408)
Query Neighborhood Hits	2923	Target Neighborhood Hits	868	Shared Neighborhood Hits	389
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

CCD46_HUMAN
NC score	0.068539 (rank : 1317)	θ value	0.21417 (rank : 1445)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1430	Shared Neighborhood Hits	490
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

CCD46_MOUSE
NC score	0.068330 (rank : 1318)	θ value	0.0736092 (rank : 1329)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1405	Shared Neighborhood Hits	490
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

TSC1_HUMAN
NC score	0.068320 (rank : 1319)	θ value	0.000602161 (rank : 1070)
Query Neighborhood Hits	2923	Target Neighborhood Hits	765	Shared Neighborhood Hits	332
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

AKA12_HUMAN
NC score	0.068263 (rank : 1320)	θ value	0.00509761 (rank : 1145)
Query Neighborhood Hits	2923	Target Neighborhood Hits	825	Shared Neighborhood Hits	366
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

STAC3_HUMAN
NC score	0.068099 (rank : 1321)	θ value	θ > 10 (rank : 3101)
Query Neighborhood Hits	2923	Target Neighborhood Hits	228	Shared Neighborhood Hits	83
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

CCD96_MOUSE
NC score	0.068078 (rank : 1322)	θ value	1.38821 (rank : 1828)
Query Neighborhood Hits	2923	Target Neighborhood Hits	704	Shared Neighborhood Hits	363
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CD45_HUMAN
NC score	0.068040 (rank : 1323)	θ value	0.163984 (rank : 1410)
Query Neighborhood Hits	2923	Target Neighborhood Hits	243	Shared Neighborhood Hits	104
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

CNTRB_MOUSE
NC score	0.067878 (rank : 1324)	θ value	1.81305 (rank : 1920)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1029	Shared Neighborhood Hits	426
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

CCD21_MOUSE
NC score	0.067709 (rank : 1325)	θ value	0.62314 (rank : 1654)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1135	Shared Neighborhood Hits	464
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

TCOF_MOUSE
NC score	0.067650 (rank : 1326)	θ value	θ > 10 (rank : 3111)
Query Neighborhood Hits	2923	Target Neighborhood Hits	471	Shared Neighborhood Hits	225
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

BAT2_HUMAN
NC score	0.067249 (rank : 1327)	θ value	0.0563607 (rank : 1302)
Query Neighborhood Hits	2923	Target Neighborhood Hits	931	Shared Neighborhood Hits	355
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

DCX_HUMAN
NC score	0.067187 (rank : 1328)	θ value	θ > 10 (rank : 2983)
Query Neighborhood Hits	2923	Target Neighborhood Hits	141	Shared Neighborhood Hits	59
SwissProt Accessions	O43602, O43911	Gene names	DCX, DBCN, LISX
Domain Architecture
Description	Neuronal migration protein doublecortin (Lissencephalin-X) (Lis-X) (Doublin).

PIBF1_HUMAN
NC score	0.067138 (rank : 1329)	θ value	0.279714 (rank : 1517)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1041	Shared Neighborhood Hits	409
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

AMGO2_MOUSE
NC score	0.067016 (rank : 1330)	θ value	5.27518 (rank : 2383)
Query Neighborhood Hits	2923	Target Neighborhood Hits	329	Shared Neighborhood Hits	124
SwissProt Accessions	Q80ZD9	Gene names	Amigo2, Ali1
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 2 precursor (AMIGO-2) (Alivin-1).

LEPR_MOUSE
NC score	0.066742 (rank : 1331)	θ value	0.365318 (rank : 1556)
Query Neighborhood Hits	2923	Target Neighborhood Hits	109	Shared Neighborhood Hits	82
SwissProt Accessions	P48356, O35686, O54986, Q61215, Q64309, Q9QWG3, Q9QWV5	Gene names	Lepr, db, Obr
Domain Architecture
Description	Leptin receptor precursor (LEP-R) (OB receptor) (OB-R) (B219) (CD295 antigen).

SLAF9_MOUSE
NC score	0.066440 (rank : 1332)	θ value	5.27518 (rank : 2514)
Query Neighborhood Hits	2923	Target Neighborhood Hits	78	Shared Neighborhood Hits	67
SwissProt Accessions	Q9D780, Q8BTK0, Q8VE93	Gene names	Slamf9
Domain Architecture	No domain graphic available
Description	SLAM family member 9 precursor.

K0586_HUMAN
NC score	0.066379 (rank : 1333)	θ value	0.0252991 (rank : 1254)
Query Neighborhood Hits	2923	Target Neighborhood Hits	311	Shared Neighborhood Hits	182
SwissProt Accessions	Q9BVV6, O60328	Gene names	KIAA0586
Domain Architecture	No domain graphic available
Description	Protein KIAA0586.

PININ_MOUSE
NC score	0.066049 (rank : 1334)	θ value	θ > 10 (rank : 3064)
Query Neighborhood Hits	2923	Target Neighborhood Hits	777	Shared Neighborhood Hits	398
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

IL27B_MOUSE
NC score	0.065926 (rank : 1335)	θ value	0.0563607 (rank : 1315)
Query Neighborhood Hits	2923	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	O35228	Gene names	Ebi3, Il17b
Domain Architecture
Description	Interleukin-27 beta chain precursor (IL-27B) (Epstein-Barr virus- induced gene 3 protein homolog).

CI039_HUMAN
NC score	0.065916 (rank : 1336)	θ value	1.81305 (rank : 1919)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1171	Shared Neighborhood Hits	448
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

RBBP6_MOUSE
NC score	0.065906 (rank : 1337)	θ value	0.163984 (rank : 1431)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1014	Shared Neighborhood Hits	405
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

STAC_HUMAN
NC score	0.065889 (rank : 1338)	θ value	θ > 10 (rank : 3103)
Query Neighborhood Hits	2923	Target Neighborhood Hits	276	Shared Neighborhood Hits	102
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

IF2P_HUMAN
NC score	0.065750 (rank : 1339)	θ value	5.27518 (rank : 2442)
Query Neighborhood Hits	2923	Target Neighborhood Hits	889	Shared Neighborhood Hits	381
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

RASF1_MOUSE
NC score	0.065741 (rank : 1340)	θ value	θ > 10 (rank : 3080)
Query Neighborhood Hits	2923	Target Neighborhood Hits	74	Shared Neighborhood Hits	37
SwissProt Accessions	Q99MK9, Q9WUF5	Gene names	Rassf1
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 1 (Protein 123F2).

TP53B_MOUSE
NC score	0.065726 (rank : 1341)	θ value	0.000158464 (rank : 1024)
Query Neighborhood Hits	2923	Target Neighborhood Hits	644	Shared Neighborhood Hits	277
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

GOGA4_HUMAN
NC score	0.065476 (rank : 1342)	θ value	0.163984 (rank : 1419)
Query Neighborhood Hits	2923	Target Neighborhood Hits	2034	Shared Neighborhood Hits	620
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

CCD11_MOUSE
NC score	0.065406 (rank : 1343)	θ value	0.365318 (rank : 1538)
Query Neighborhood Hits	2923	Target Neighborhood Hits	498	Shared Neighborhood Hits	246
SwissProt Accessions	Q9D439	Gene names	Ccdc11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

IF3A_MOUSE
NC score	0.065294 (rank : 1344)	θ value	0.279714 (rank : 1507)
Query Neighborhood Hits	2923	Target Neighborhood Hits	871	Shared Neighborhood Hits	391
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

AKAP9_HUMAN
NC score	0.065195 (rank : 1345)	θ value	0.000461057 (rank : 1050)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1710	Shared Neighborhood Hits	542
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

K0555_HUMAN
NC score	0.065169 (rank : 1346)	θ value	1.81305 (rank : 1948)
Query Neighborhood Hits	2923	Target Neighborhood Hits	880	Shared Neighborhood Hits	366
SwissProt Accessions	Q96AA8, O60302	Gene names	KIAA0555
Domain Architecture	No domain graphic available
Description	Protein KIAA0555.

AMGO1_HUMAN
NC score	0.064642 (rank : 1347)	θ value	0.62314 (rank : 1647)
Query Neighborhood Hits	2923	Target Neighborhood Hits	353	Shared Neighborhood Hits	140
SwissProt Accessions	Q86WK6, Q8IW71, Q9ULQ7	Gene names	AMIGO1, ALI2, AMIGO, KIAA1163
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 1 precursor (AMIGO-1) (Alivin-2).

GOGB1_HUMAN
NC score	0.064535 (rank : 1348)	θ value	0.00509761 (rank : 1147)
Query Neighborhood Hits	2923	Target Neighborhood Hits	2297	Shared Neighborhood Hits	668
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

SPRR3_HUMAN
NC score	0.064458 (rank : 1349)	θ value	2.44474e-05 (rank : 960)
Query Neighborhood Hits	2923	Target Neighborhood Hits	102	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UBC9, O75597, Q4ZGI7, Q5T525, Q8NET7, Q9UDG3	Gene names	SPRR3, SPRC
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta) (Esophagin) (22 kDa pancornulin).

GOGA4_MOUSE
NC score	0.064306 (rank : 1350)	θ value	0.0563607 (rank : 1309)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1939	Shared Neighborhood Hits	607
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

TAF3_MOUSE
NC score	0.064273 (rank : 1351)	θ value	0.00869519 (rank : 1192)
Query Neighborhood Hits	2923	Target Neighborhood Hits	463	Shared Neighborhood Hits	251
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

CCD19_HUMAN
NC score	0.064255 (rank : 1352)	θ value	θ > 10 (rank : 2959)
Query Neighborhood Hits	2923	Target Neighborhood Hits	639	Shared Neighborhood Hits	312
SwissProt Accessions	Q9UL16	Gene names	CCDC19, NESG1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 19 (Nasopharyngeal epithelium- specific protein 1).

RBM25_HUMAN
NC score	0.064254 (rank : 1353)	θ value	θ > 10 (rank : 3082)
Query Neighborhood Hits	2923	Target Neighborhood Hits	682	Shared Neighborhood Hits	327
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

MY18A_MOUSE
NC score	0.064219 (rank : 1354)	θ value	1.06291 (rank : 1795)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1989	Shared Neighborhood Hits	618
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

PCNT_HUMAN
NC score	0.064211 (rank : 1355)	θ value	0.365318 (rank : 1562)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1551	Shared Neighborhood Hits	529
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

SLAF8_MOUSE
NC score	0.064090 (rank : 1356)	θ value	0.0961366 (rank : 1379)
Query Neighborhood Hits	2923	Target Neighborhood Hits	52	Shared Neighborhood Hits	48
SwissProt Accessions	Q9D3G2, Q8R3T7	Gene names	Slamf8, Blame
Domain Architecture	No domain graphic available
Description	SLAM family member 8 precursor (B-lymphocyte activator macrophage expressed).

OGFR_HUMAN
NC score	0.063992 (rank : 1357)	θ value	0.0961366 (rank : 1376)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1582	Shared Neighborhood Hits	441
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

CD226_MOUSE
NC score	0.063984 (rank : 1358)	θ value	0.163984 (rank : 1409)
Query Neighborhood Hits	2923	Target Neighborhood Hits	64	Shared Neighborhood Hits	58
SwissProt Accessions	Q8K4F0	Gene names	Cd226, Pta1
Domain Architecture
Description	CD226 antigen precursor (Platelet and T-cell activation antigen 1).

IF3A_HUMAN
NC score	0.063939 (rank : 1359)	θ value	0.813845 (rank : 1729)
Query Neighborhood Hits	2923	Target Neighborhood Hits	875	Shared Neighborhood Hits	389
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

ITSN1_MOUSE
NC score	0.063862 (rank : 1360)	θ value	0.47712 (rank : 1607)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1669	Shared Neighborhood Hits	593
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

TPR_HUMAN
NC score	0.063854 (rank : 1361)	θ value	0.00869519 (rank : 1194)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1921	Shared Neighborhood Hits	609
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

DGKD_HUMAN
NC score	0.063767 (rank : 1362)	θ value	θ > 10 (rank : 2985)
Query Neighborhood Hits	2923	Target Neighborhood Hits	231	Shared Neighborhood Hits	92
SwissProt Accessions	Q16760, Q14158, Q6PK55, Q8NG53	Gene names	DGKD, KIAA0145
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase delta (EC 2.7.1.107) (Diglyceride kinase delta) (DGK-delta) (DAG kinase delta) (130 kDa diacylglycerol kinase).

RGS3_MOUSE
NC score	0.063756 (rank : 1363)	θ value	6.43352e-06 (rank : 919)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1621	Shared Neighborhood Hits	506
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

CCD41_MOUSE
NC score	0.063575 (rank : 1364)	θ value	2.36792 (rank : 2022)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1399	Shared Neighborhood Hits	490
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

ZN291_HUMAN
NC score	0.063507 (rank : 1365)	θ value	0.125558 (rank : 1405)
Query Neighborhood Hits	2923	Target Neighborhood Hits	647	Shared Neighborhood Hits	317
SwissProt Accessions	Q9BY12	Gene names	ZNF291
Domain Architecture
Description	Zinc finger protein 291.

NCOR2_HUMAN
NC score	0.063398 (rank : 1366)	θ value	3.0926 (rank : 2197)
Query Neighborhood Hits	2923	Target Neighborhood Hits	870	Shared Neighborhood Hits	431
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

TCOF_HUMAN
NC score	0.063378 (rank : 1367)	θ value	0.47712 (rank : 1640)
Query Neighborhood Hits	2923	Target Neighborhood Hits	543	Shared Neighborhood Hits	238
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

CA065_HUMAN
NC score	0.063261 (rank : 1368)	θ value	6.88961 (rank : 2555)
Query Neighborhood Hits	2923	Target Neighborhood Hits	469	Shared Neighborhood Hits	266
SwissProt Accessions	Q8N715, Q8N746, Q8NA93	Gene names	C1orf65
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf65.

PCNT_MOUSE
NC score	0.063248 (rank : 1369)	θ value	1.06291 (rank : 1802)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1207	Shared Neighborhood Hits	440
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

CD86_MOUSE
NC score	0.063210 (rank : 1370)	θ value	2.36792 (rank : 2026)
Query Neighborhood Hits	2923	Target Neighborhood Hits	85	Shared Neighborhood Hits	75
SwissProt Accessions	P42082	Gene names	Cd86
Domain Architecture
Description	T-lymphocyte activation antigen CD86 precursor (Activation B7-2 antigen) (Early T-cell costimulatory molecule 1) (ETC-1).

LRC45_MOUSE
NC score	0.063154 (rank : 1371)	θ value	1.38821 (rank : 1861)
Query Neighborhood Hits	2923	Target Neighborhood Hits	959	Shared Neighborhood Hits	386
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

GOGA1_HUMAN
NC score	0.063136 (rank : 1372)	θ value	0.0330416 (rank : 1266)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1222	Shared Neighborhood Hits	445
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

DCX_MOUSE
NC score	0.063029 (rank : 1373)	θ value	θ > 10 (rank : 2984)
Query Neighborhood Hits	2923	Target Neighborhood Hits	124	Shared Neighborhood Hits	39
SwissProt Accessions	O88809	Gene names	Dcx, Dcn
Domain Architecture
Description	Neuronal migration protein doublecortin (Lissencephalin-X) (Lis-X) (Doublin).

CD45_MOUSE
NC score	0.062976 (rank : 1374)	θ value	5.27518 (rank : 2397)
Query Neighborhood Hits	2923	Target Neighborhood Hits	178	Shared Neighborhood Hits	88
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

CS016_HUMAN
NC score	0.062975 (rank : 1375)	θ value	0.163984 (rank : 1413)
Query Neighborhood Hits	2923	Target Neighborhood Hits	310	Shared Neighborhood Hits	168
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

SDCG8_HUMAN
NC score	0.062968 (rank : 1376)	θ value	θ > 10 (rank : 3090)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1002	Shared Neighborhood Hits	406
SwissProt Accessions	Q86SQ7, O60527, Q3ZCR6, Q8N5F2, Q9P0F1	Gene names	SDCCAG8, CCCAP
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (hCCCAP) (Antigen NY-CO-8).

CING_MOUSE
NC score	0.062935 (rank : 1377)	θ value	0.365318 (rank : 1540)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1432	Shared Neighborhood Hits	493
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

NIPBL_HUMAN
NC score	0.062916 (rank : 1378)	θ value	0.0330416 (rank : 1271)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1311	Shared Neighborhood Hits	512
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

KTN1_MOUSE
NC score	0.062793 (rank : 1379)	θ value	0.62314 (rank : 1675)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1324	Shared Neighborhood Hits	487
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

WASIP_HUMAN
NC score	0.062754 (rank : 1380)	θ value	θ > 10 (rank : 3127)
Query Neighborhood Hits	2923	Target Neighborhood Hits	458	Shared Neighborhood Hits	229
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

BRD4_HUMAN
NC score	0.062683 (rank : 1381)	θ value	0.00869519 (rank : 1176)
Query Neighborhood Hits	2923	Target Neighborhood Hits	851	Shared Neighborhood Hits	448
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

RB6I2_HUMAN
NC score	0.062674 (rank : 1382)	θ value	0.0736092 (rank : 1349)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1584	Shared Neighborhood Hits	526
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

CP250_HUMAN
NC score	0.062673 (rank : 1383)	θ value	0.21417 (rank : 1451)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1805	Shared Neighborhood Hits	556
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

CP135_MOUSE
NC score	0.062660 (rank : 1384)	θ value	0.000461057 (rank : 1051)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1278	Shared Neighborhood Hits	451
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

GSCR1_HUMAN
NC score	0.062529 (rank : 1385)	θ value	θ > 10 (rank : 3010)
Query Neighborhood Hits	2923	Target Neighborhood Hits	674	Shared Neighborhood Hits	292
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

LRC45_HUMAN
NC score	0.062518 (rank : 1386)	θ value	0.0431538 (rank : 1290)
Query Neighborhood Hits	2923	Target Neighborhood Hits	933	Shared Neighborhood Hits	396
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

MY18A_HUMAN
NC score	0.062448 (rank : 1387)	θ value	6.88961 (rank : 2653)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1929	Shared Neighborhood Hits	603
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

TRIPB_HUMAN
NC score	0.062398 (rank : 1388)	θ value	0.0252991 (rank : 1258)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1587	Shared Neighborhood Hits	525
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

IFT81_MOUSE
NC score	0.062229 (rank : 1389)	θ value	1.81305 (rank : 1943)
Query Neighborhood Hits	2923	Target Neighborhood Hits	959	Shared Neighborhood Hits	392
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

CCD96_HUMAN
NC score	0.062201 (rank : 1390)	θ value	θ > 10 (rank : 2962)
Query Neighborhood Hits	2923	Target Neighborhood Hits	595	Shared Neighborhood Hits	321
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CCD21_HUMAN
NC score	0.062161 (rank : 1391)	θ value	0.0431538 (rank : 1282)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1228	Shared Neighborhood Hits	467
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

BRD4_MOUSE
NC score	0.062036 (rank : 1392)	θ value	0.0961366 (rank : 1358)
Query Neighborhood Hits	2923	Target Neighborhood Hits	845	Shared Neighborhood Hits	447
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

UN13B_HUMAN
NC score	0.061981 (rank : 1393)	θ value	θ > 10 (rank : 3119)
Query Neighborhood Hits	2923	Target Neighborhood Hits	217	Shared Neighborhood Hits	66
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

CI093_HUMAN
NC score	0.061958 (rank : 1394)	θ value	2.36792 (rank : 2031)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1088	Shared Neighborhood Hits	418
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

CJ118_MOUSE
NC score	0.061918 (rank : 1395)	θ value	0.00869519 (rank : 1177)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1132	Shared Neighborhood Hits	427
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

TACC2_MOUSE
NC score	0.061887 (rank : 1396)	θ value	0.47712 (rank : 1637)
Query Neighborhood Hits	2923	Target Neighborhood Hits	774	Shared Neighborhood Hits	386
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

SMC2_HUMAN
NC score	0.061859 (rank : 1397)	θ value	0.0193708 (rank : 1242)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1405	Shared Neighborhood Hits	513
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

CCD39_MOUSE
NC score	0.061852 (rank : 1398)	θ value	0.279714 (rank : 1485)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1026	Shared Neighborhood Hits	407
SwissProt Accessions	Q9D5Y1, Q8CDG6	Gene names	Ccdc39, D3Ertd789e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

VAV_HUMAN
NC score	0.061570 (rank : 1399)	θ value	θ > 10 (rank : 3125)
Query Neighborhood Hits	2923	Target Neighborhood Hits	452	Shared Neighborhood Hits	135
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

CROCC_MOUSE
NC score	0.061533 (rank : 1400)	θ value	1.81305 (rank : 1922)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1460	Shared Neighborhood Hits	502
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

FA47B_HUMAN
NC score	0.061484 (rank : 1401)	θ value	7.59969e-07 (rank : 865)
Query Neighborhood Hits	2923	Target Neighborhood Hits	431	Shared Neighborhood Hits	164
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

BAT2_MOUSE
NC score	0.061468 (rank : 1402)	θ value	0.0736092 (rank : 1327)
Query Neighborhood Hits	2923	Target Neighborhood Hits	947	Shared Neighborhood Hits	359
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

IGSF8_HUMAN
NC score	0.061450 (rank : 1403)	θ value	θ > 10 (rank : 3022)
Query Neighborhood Hits	2923	Target Neighborhood Hits	88	Shared Neighborhood Hits	52
SwissProt Accessions	Q969P0, Q8NG09, Q96DP4, Q9BTG9	Gene names	IGSF8, CD81P3, EWI2, KCT4
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 8 precursor (CD81 partner 3) (Glu- Trp-Ile EWI motif-containing protein 2) (EWI-2) (Keratinocytes- associated transmembrane protein 4) (KCT-4) (LIR-D1) (CD316 antigen).

ENL_HUMAN
NC score	0.061406 (rank : 1404)	θ value	0.163984 (rank : 1417)
Query Neighborhood Hits	2923	Target Neighborhood Hits	305	Shared Neighborhood Hits	156
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

REST_HUMAN
NC score	0.061394 (rank : 1405)	θ value	0.00665767 (rank : 1173)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1605	Shared Neighborhood Hits	539
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

CE152_HUMAN
NC score	0.061373 (rank : 1406)	θ value	2.36792 (rank : 2027)
Query Neighborhood Hits	2923	Target Neighborhood Hits	976	Shared Neighborhood Hits	389
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

GRAP1_HUMAN
NC score	0.061367 (rank : 1407)	θ value	0.0563607 (rank : 1310)
Query Neighborhood Hits	2923	Target Neighborhood Hits	944	Shared Neighborhood Hits	371
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

CAF1A_MOUSE
NC score	0.061360 (rank : 1408)	θ value	0.21417 (rank : 1442)
Query Neighborhood Hits	2923	Target Neighborhood Hits	736	Shared Neighborhood Hits	346
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

RB6I2_MOUSE
NC score	0.061290 (rank : 1409)	θ value	4.03905 (rank : 2339)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1433	Shared Neighborhood Hits	502
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

RBCC1_HUMAN
NC score	0.061168 (rank : 1410)	θ value	0.365318 (rank : 1564)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1023	Shared Neighborhood Hits	401
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

CN145_HUMAN
NC score	0.061103 (rank : 1411)	θ value	0.813845 (rank : 1714)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1196	Shared Neighborhood Hits	455
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

TAU_HUMAN
NC score	0.061079 (rank : 1412)	θ value	1.38821 (rank : 1895)
Query Neighborhood Hits	2923	Target Neighborhood Hits	448	Shared Neighborhood Hits	195
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

ENAH_MOUSE
NC score	0.061056 (rank : 1413)	θ value	θ > 10 (rank : 2992)
Query Neighborhood Hits	2923	Target Neighborhood Hits	919	Shared Neighborhood Hits	429
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

PTN11_HUMAN
NC score	0.061002 (rank : 1414)	θ value	θ > 10 (rank : 3071)
Query Neighborhood Hits	2923	Target Neighborhood Hits	227	Shared Neighborhood Hits	85
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

CING_HUMAN
NC score	0.060943 (rank : 1415)	θ value	6.88961 (rank : 2567)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1275	Shared Neighborhood Hits	468
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

CF060_HUMAN
NC score	0.060933 (rank : 1416)	θ value	θ > 10 (rank : 2971)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1270	Shared Neighborhood Hits	469
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

PTN11_MOUSE
NC score	0.060930 (rank : 1417)	θ value	θ > 10 (rank : 3072)
Query Neighborhood Hits	2923	Target Neighborhood Hits	227	Shared Neighborhood Hits	85
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

GOGA1_MOUSE
NC score	0.060844 (rank : 1418)	θ value	0.62314 (rank : 1668)
Query Neighborhood Hits	2923	Target Neighborhood Hits	994	Shared Neighborhood Hits	396
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

XE7_HUMAN
NC score	0.060831 (rank : 1419)	θ value	θ > 10 (rank : 3130)
Query Neighborhood Hits	2923	Target Neighborhood Hits	738	Shared Neighborhood Hits	338
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

GCC2_MOUSE
NC score	0.060751 (rank : 1420)	θ value	0.0193708 (rank : 1234)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1619	Shared Neighborhood Hits	535
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

LCP2_HUMAN
NC score	0.060751 (rank : 1421)	θ value	0.00390308 (rank : 1140)
Query Neighborhood Hits	2923	Target Neighborhood Hits	531	Shared Neighborhood Hits	215
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

CCD41_HUMAN
NC score	0.060739 (rank : 1422)	θ value	4.03905 (rank : 2260)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1139	Shared Neighborhood Hits	424
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

CJ012_HUMAN
NC score	0.060646 (rank : 1423)	θ value	0.21417 (rank : 1447)
Query Neighborhood Hits	2923	Target Neighborhood Hits	467	Shared Neighborhood Hits	204
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

AN30A_HUMAN
NC score	0.060645 (rank : 1424)	θ value	4.1701e-05 (rank : 972)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1119	Shared Neighborhood Hits	424
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

AMGO3_HUMAN
NC score	0.060635 (rank : 1425)	θ value	θ > 10 (rank : 2937)
Query Neighborhood Hits	2923	Target Neighborhood Hits	276	Shared Neighborhood Hits	100
SwissProt Accessions	Q86WK7, Q96JH6	Gene names	AMIGO3, ALI3, KIAA1851
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 3 precursor (AMIGO-3) (Alivin-3).

CCD45_MOUSE
NC score	0.060548 (rank : 1426)	θ value	1.06291 (rank : 1769)
Query Neighborhood Hits	2923	Target Neighborhood Hits	663	Shared Neighborhood Hits	330
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

CP250_MOUSE
NC score	0.060504 (rank : 1427)	θ value	0.0736092 (rank : 1330)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1583	Shared Neighborhood Hits	519
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

TAF4_HUMAN
NC score	0.060495 (rank : 1428)	θ value	θ > 10 (rank : 3109)
Query Neighborhood Hits	2923	Target Neighborhood Hits	687	Shared Neighborhood Hits	313
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

PRLR_HUMAN
NC score	0.060366 (rank : 1429)	θ value	0.0148317 (rank : 1223)
Query Neighborhood Hits	2923	Target Neighborhood Hits	95	Shared Neighborhood Hits	66
SwissProt Accessions	P16471, Q16354, Q9BX87	Gene names	PRLR
Domain Architecture
Description	Prolactin receptor precursor (PRL-R).

I27RA_MOUSE
NC score	0.060355 (rank : 1430)	θ value	0.0736092 (rank : 1339)
Query Neighborhood Hits	2923	Target Neighborhood Hits	55	Shared Neighborhood Hits	45
SwissProt Accessions	O70394	Gene names	Il27ra, Tccr, Wsx1
Domain Architecture	No domain graphic available
Description	Interleukin-27 receptor alpha chain precursor (IL-27R-alpha) (WSX-1) (Type I T-cell cytokine receptor) (TCCR).

SYCP1_HUMAN
NC score	0.060329 (rank : 1431)	θ value	0.813845 (rank : 1748)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1313	Shared Neighborhood Hits	478
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

CHIO_HUMAN
NC score	0.060329 (rank : 1432)	θ value	θ > 10 (rank : 2974)
Query Neighborhood Hits	2923	Target Neighborhood Hits	220	Shared Neighborhood Hits	71
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

SDCG8_MOUSE
NC score	0.060318 (rank : 1433)	θ value	θ > 10 (rank : 3091)
Query Neighborhood Hits	2923	Target Neighborhood Hits	886	Shared Neighborhood Hits	376
SwissProt Accessions	Q80UF4	Gene names	Sdccag8, Cccap
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (mCCCAP).

FA47A_HUMAN
NC score	0.060229 (rank : 1434)	θ value	0.62314 (rank : 1663)
Query Neighborhood Hits	2923	Target Neighborhood Hits	451	Shared Neighborhood Hits	194
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

SYCP1_MOUSE
NC score	0.060217 (rank : 1435)	θ value	0.0148317 (rank : 1225)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1456	Shared Neighborhood Hits	515
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

ICOSL_HUMAN
NC score	0.060187 (rank : 1436)	θ value	θ > 10 (rank : 3019)
Query Neighborhood Hits	2923	Target Neighborhood Hits	70	Shared Neighborhood Hits	63
SwissProt Accessions	O75144, Q9HD18, Q9NRQ1	Gene names	ICOSLG, B7H2, B7RP1, ICOSL, KIAA0653
Domain Architecture
Description	ICOS ligand precursor (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (CD275 antigen).

GCC2_HUMAN
NC score	0.060115 (rank : 1437)	θ value	0.125558 (rank : 1388)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1558	Shared Neighborhood Hits	500
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

RBP24_HUMAN
NC score	0.060049 (rank : 1438)	θ value	0.125558 (rank : 1397)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1559	Shared Neighborhood Hits	499
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

TRIM9_HUMAN
NC score	0.060036 (rank : 1439)	θ value	0.0193708 (rank : 1246)
Query Neighborhood Hits	2923	Target Neighborhood Hits	294	Shared Neighborhood Hits	99
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

PEPL_MOUSE
NC score	0.059998 (rank : 1440)	θ value	3.0926 (rank : 2205)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1105	Shared Neighborhood Hits	437
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

VAV3_MOUSE
NC score	0.059973 (rank : 1441)	θ value	θ > 10 (rank : 3124)
Query Neighborhood Hits	2923	Target Neighborhood Hits	404	Shared Neighborhood Hits	127
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

VAV3_HUMAN
NC score	0.059963 (rank : 1442)	θ value	θ > 10 (rank : 3123)
Query Neighborhood Hits	2923	Target Neighborhood Hits	398	Shared Neighborhood Hits	118
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

SWP70_MOUSE
NC score	0.059958 (rank : 1443)	θ value	θ > 10 (rank : 3108)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1097	Shared Neighborhood Hits	421
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SET1A_HUMAN
NC score	0.059897 (rank : 1444)	θ value	6.88961 (rank : 2689)
Query Neighborhood Hits	2923	Target Neighborhood Hits	690	Shared Neighborhood Hits	312
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

HMMR_MOUSE
NC score	0.059874 (rank : 1445)	θ value	0.813845 (rank : 1727)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1178	Shared Neighborhood Hits	445
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

FLIP1_HUMAN
NC score	0.059867 (rank : 1446)	θ value	0.163984 (rank : 1418)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1405	Shared Neighborhood Hits	490
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

RAD50_MOUSE
NC score	0.059865 (rank : 1447)	θ value	0.279714 (rank : 1519)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1366	Shared Neighborhood Hits	460
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

AZI1_HUMAN
NC score	0.059815 (rank : 1448)	θ value	θ > 10 (rank : 2948)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1000	Shared Neighborhood Hits	399
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

RAD50_HUMAN
NC score	0.059795 (rank : 1449)	θ value	1.38821 (rank : 1875)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1317	Shared Neighborhood Hits	453
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

GAS8_MOUSE
NC score	0.059778 (rank : 1450)	θ value	θ > 10 (rank : 2996)
Query Neighborhood Hits	2923	Target Neighborhood Hits	622	Shared Neighborhood Hits	298
SwissProt Accessions	Q60779, Q99L71	Gene names	Gas8, Gas11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

CROCC_HUMAN
NC score	0.059768 (rank : 1451)	θ value	1.06291 (rank : 1772)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1409	Shared Neighborhood Hits	472
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

UN13B_MOUSE
NC score	0.059718 (rank : 1452)	θ value	θ > 10 (rank : 3120)
Query Neighborhood Hits	2923	Target Neighborhood Hits	210	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

DESP_HUMAN
NC score	0.059695 (rank : 1453)	θ value	0.21417 (rank : 1454)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1470	Shared Neighborhood Hits	498
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

NIN_HUMAN
NC score	0.059677 (rank : 1454)	θ value	1.06291 (rank : 1801)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1416	Shared Neighborhood Hits	476
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

CHIN_MOUSE
NC score	0.059599 (rank : 1455)	θ value	θ > 10 (rank : 2973)
Query Neighborhood Hits	2923	Target Neighborhood Hits	229	Shared Neighborhood Hits	72
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

ITSN1_HUMAN
NC score	0.059568 (rank : 1456)	θ value	θ > 10 (rank : 3030)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1757	Shared Neighborhood Hits	598
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

CK5P2_HUMAN
NC score	0.059488 (rank : 1457)	θ value	1.38821 (rank : 1830)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1433	Shared Neighborhood Hits	517
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

MUC_MOUSE
NC score	0.059434 (rank : 1458)	θ value	0.0113563 (rank : 1204)
Query Neighborhood Hits	2923	Target Neighborhood Hits	242	Shared Neighborhood Hits	90
SwissProt Accessions	P01872	Gene names
Domain Architecture	No domain graphic available
Description	Ig mu chain C region secreted form.

NEST_HUMAN
NC score	0.059426 (rank : 1459)	θ value	5.27518 (rank : 2467)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1305	Shared Neighborhood Hits	495
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

CE290_HUMAN
NC score	0.059339 (rank : 1460)	θ value	2.36792 (rank : 2028)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1553	Shared Neighborhood Hits	511
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

GRAP1_MOUSE
NC score	0.059331 (rank : 1461)	θ value	θ > 10 (rank : 3002)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1234	Shared Neighborhood Hits	452
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

OPTN_MOUSE
NC score	0.059290 (rank : 1462)	θ value	5.27518 (rank : 2470)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1120	Shared Neighborhood Hits	436
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

RRBP1_MOUSE
NC score	0.059278 (rank : 1463)	θ value	0.0961366 (rank : 1378)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1650	Shared Neighborhood Hits	544
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

MUCM_MOUSE
NC score	0.059253 (rank : 1464)	θ value	0.0148317 (rank : 1220)
Query Neighborhood Hits	2923	Target Neighborhood Hits	242	Shared Neighborhood Hits	89
SwissProt Accessions	P01873	Gene names
Domain Architecture	No domain graphic available
Description	Ig mu chain C region membrane-bound form.

IFT81_HUMAN
NC score	0.059147 (rank : 1465)	θ value	θ > 10 (rank : 3021)
Query Neighborhood Hits	2923	Target Neighborhood Hits	893	Shared Neighborhood Hits	383
SwissProt Accessions	Q8WYA0, Q8NB51, Q9BSV2, Q9UNY8	Gene names	IFT81, CDV1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

HMMR_HUMAN
NC score	0.059146 (rank : 1466)	θ value	1.38821 (rank : 1851)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1082	Shared Neighborhood Hits	401
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

CHIN_HUMAN
NC score	0.059114 (rank : 1467)	θ value	θ > 10 (rank : 2972)
Query Neighborhood Hits	2923	Target Neighborhood Hits	227	Shared Neighborhood Hits	72
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CD86_HUMAN
NC score	0.058993 (rank : 1468)	θ value	3.0926 (rank : 2145)
Query Neighborhood Hits	2923	Target Neighborhood Hits	85	Shared Neighborhood Hits	69
SwissProt Accessions	P42081, Q13655, Q7M4L5	Gene names	CD86, CD28LG2
Domain Architecture
Description	T-lymphocyte activation antigen CD86 precursor (Activation B7-2 antigen) (CTLA-4 counter-receptor B7.2) (B70) (FUN-1) (BU63).

TAXB1_HUMAN
NC score	0.058935 (rank : 1469)	θ value	0.47712 (rank : 1639)
Query Neighborhood Hits	2923	Target Neighborhood Hits	829	Shared Neighborhood Hits	355
SwissProt Accessions	Q86VP1, O60398, O95770, Q13311, Q9BQG5, Q9UI88	Gene names	TAX1BP1, T6BP
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 (TRAF6-binding protein).

PRLR_MOUSE
NC score	0.058921 (rank : 1470)	θ value	0.00390308 (rank : 1141)
Query Neighborhood Hits	2923	Target Neighborhood Hits	82	Shared Neighborhood Hits	59
SwissProt Accessions	Q08501, P15212, P15213, Q62099	Gene names	Prlr
Domain Architecture
Description	Prolactin receptor precursor (PRL-R).

DGKH_HUMAN
NC score	0.058917 (rank : 1471)	θ value	θ > 10 (rank : 2986)
Query Neighborhood Hits	2923	Target Neighborhood Hits	255	Shared Neighborhood Hits	92
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

CAF1A_HUMAN
NC score	0.058900 (rank : 1472)	θ value	1.06291 (rank : 1768)
Query Neighborhood Hits	2923	Target Neighborhood Hits	750	Shared Neighborhood Hits	342
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

YLPM1_HUMAN
NC score	0.058841 (rank : 1473)	θ value	0.0193708 (rank : 1249)
Query Neighborhood Hits	2923	Target Neighborhood Hits	670	Shared Neighborhood Hits	269
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

SLAF5_HUMAN
NC score	0.058821 (rank : 1474)	θ value	1.38821 (rank : 1886)
Query Neighborhood Hits	2923	Target Neighborhood Hits	65	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UIB8, O15430, O95266, O95660, Q5H9R1, Q6FHA8, Q8WLP1, Q8WWI8, Q9UF04, Q9UIB6, Q9UIB7, Q9UIT7	Gene names	CD84, SLAMF5
Domain Architecture	No domain graphic available
Description	SLAM family member 5 precursor (Signaling lymphocytic activation molecule 5) (Leukocyte differentiation antigen CD84) (CD84 antigen) (Cell surface antigen MAX.3) (Hly9-beta).

GAS8_HUMAN
NC score	0.058802 (rank : 1475)	θ value	θ > 10 (rank : 2995)
Query Neighborhood Hits	2923	Target Neighborhood Hits	819	Shared Neighborhood Hits	357
SwissProt Accessions	O95995	Gene names	GAS8, GAS11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

TAF3_HUMAN
NC score	0.058723 (rank : 1476)	θ value	1.38821 (rank : 1894)
Query Neighborhood Hits	2923	Target Neighborhood Hits	568	Shared Neighborhood Hits	289
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

PTPRG_HUMAN
NC score	0.058673 (rank : 1477)	θ value	0.00102713 (rank : 1091)
Query Neighborhood Hits	2923	Target Neighborhood Hits	231	Shared Neighborhood Hits	98
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

MY18B_HUMAN
NC score	0.058661 (rank : 1478)	θ value	θ > 10 (rank : 3048)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1299	Shared Neighborhood Hits	485
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

KTN1_HUMAN
NC score	0.058580 (rank : 1479)	θ value	0.0252991 (rank : 1256)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1197	Shared Neighborhood Hits	425
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

CASP_MOUSE
NC score	0.058457 (rank : 1480)	θ value	0.21417 (rank : 1443)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1152	Shared Neighborhood Hits	432
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

GOGA6_HUMAN
NC score	0.058443 (rank : 1481)	θ value	θ > 10 (rank : 3001)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1007	Shared Neighborhood Hits	401
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

NUMA1_HUMAN
NC score	0.058430 (rank : 1482)	θ value	2.36792 (rank : 2086)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1523	Shared Neighborhood Hits	504
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

CCD93_HUMAN
NC score	0.058338 (rank : 1483)	θ value	0.21417 (rank : 1446)
Query Neighborhood Hits	2923	Target Neighborhood Hits	600	Shared Neighborhood Hits	290
SwissProt Accessions	Q567U6, Q4LE78, Q53TJ2, Q8TBX5, Q9H6R5, Q9NV15	Gene names	CCDC93
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 93.

NEMO_HUMAN
NC score	0.058296 (rank : 1484)	θ value	θ > 10 (rank : 3053)
Query Neighborhood Hits	2923	Target Neighborhood Hits	820	Shared Neighborhood Hits	354
SwissProt Accessions	Q9Y6K9	Gene names	IKBKG, FIP3, NEMO
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (FIP-3).

CYLN2_HUMAN
NC score	0.058289 (rank : 1485)	θ value	1.06291 (rank : 1775)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1004	Shared Neighborhood Hits	403
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

ZAN_HUMAN
NC score	0.058277 (rank : 1486)	θ value	0.00298849 (rank : 1134)
Query Neighborhood Hits	2923	Target Neighborhood Hits	679	Shared Neighborhood Hits	221
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

CENPF_HUMAN
NC score	0.058266 (rank : 1487)	θ value	0.163984 (rank : 1412)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1932	Shared Neighborhood Hits	569
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

ENAH_HUMAN
NC score	0.058245 (rank : 1488)	θ value	θ > 10 (rank : 2991)
Query Neighborhood Hits	2923	Target Neighborhood Hits	784	Shared Neighborhood Hits	389
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

SPR1B_MOUSE
NC score	0.058167 (rank : 1489)	θ value	2.88788e-06 (rank : 901)
Query Neighborhood Hits	2923	Target Neighborhood Hits	395	Shared Neighborhood Hits	130
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

PHLB1_HUMAN
NC score	0.058106 (rank : 1490)	θ value	0.279714 (rank : 1516)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1038	Shared Neighborhood Hits	434
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

SELPL_MOUSE
NC score	0.058097 (rank : 1491)	θ value	0.62314 (rank : 1689)
Query Neighborhood Hits	2923	Target Neighborhood Hits	588	Shared Neighborhood Hits	243
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

RABE1_MOUSE
NC score	0.057979 (rank : 1492)	θ value	8.99809 (rank : 2863)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1105	Shared Neighborhood Hits	433
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

AMGO3_MOUSE
NC score	0.057930 (rank : 1493)	θ value	θ > 10 (rank : 2938)
Query Neighborhood Hits	2923	Target Neighborhood Hits	276	Shared Neighborhood Hits	95
SwissProt Accessions	Q8C2S7, Q6ZPH1, Q8CEB3	Gene names	Amigo3, Ali3, Kiaa1851
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 3 precursor (AMIGO-3) (Alivin-3).

PRB3_HUMAN
NC score	0.057895 (rank : 1494)	θ value	θ > 10 (rank : 3066)
Query Neighborhood Hits	2923	Target Neighborhood Hits	318	Shared Neighborhood Hits	149
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

MD1L1_MOUSE
NC score	0.057888 (rank : 1495)	θ value	θ > 10 (rank : 3042)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1001	Shared Neighborhood Hits	384
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

TMF1_HUMAN
NC score	0.057813 (rank : 1496)	θ value	5.27518 (rank : 2525)
Query Neighborhood Hits	2923	Target Neighborhood Hits	987	Shared Neighborhood Hits	395
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

TAXB1_MOUSE
NC score	0.057766 (rank : 1497)	θ value	0.62314 (rank : 1696)
Query Neighborhood Hits	2923	Target Neighborhood Hits	886	Shared Neighborhood Hits	363
SwissProt Accessions	Q3UKC1, Q91YT6, Q9CVF0, Q9DC45	Gene names	Tax1bp1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 homolog.

BT3A3_HUMAN
NC score	0.057766 (rank : 1498)	θ value	0.0193708 (rank : 1229)
Query Neighborhood Hits	2923	Target Neighborhood Hits	233	Shared Neighborhood Hits	152
SwissProt Accessions	O00478	Gene names	BTN3A3, BTF3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A3 precursor.

CASP_HUMAN
NC score	0.057760 (rank : 1499)	θ value	0.813845 (rank : 1710)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1131	Shared Neighborhood Hits	432
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

HIP1_HUMAN
NC score	0.057709 (rank : 1500)	θ value	0.47712 (rank : 1604)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1016	Shared Neighborhood Hits	399
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

SAS6_MOUSE
NC score	0.057703 (rank : 1501)	θ value	0.163984 (rank : 1432)
Query Neighborhood Hits	2923	Target Neighborhood Hits	931	Shared Neighborhood Hits	371
SwissProt Accessions	Q80UK7, Q9CYT4	Gene names	Sass6, Sas6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog.

NCOA6_HUMAN
NC score	0.057684 (rank : 1502)	θ value	0.0193708 (rank : 1240)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1202	Shared Neighborhood Hits	413
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

IWS1_HUMAN
NC score	0.057618 (rank : 1503)	θ value	0.000786445 (rank : 1075)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1241	Shared Neighborhood Hits	438
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

GOGA3_MOUSE
NC score	0.057588 (rank : 1504)	θ value	1.06291 (rank : 1779)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1437	Shared Neighborhood Hits	477
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

REST_MOUSE
NC score	0.057544 (rank : 1505)	θ value	0.47712 (rank : 1627)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1506	Shared Neighborhood Hits	496
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

MYH11_MOUSE
NC score	0.057513 (rank : 1506)	θ value	0.00665767 (rank : 1169)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1777	Shared Neighborhood Hits	565
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

GP73_MOUSE
NC score	0.057463 (rank : 1507)	θ value	0.125558 (rank : 1389)
Query Neighborhood Hits	2923	Target Neighborhood Hits	506	Shared Neighborhood Hits	271
SwissProt Accessions	Q91XA2	Gene names	Golph2
Domain Architecture	No domain graphic available
Description	Golgi phosphoprotein 2 (Golgi membrane protein GP73).

CK5P2_MOUSE
NC score	0.057409 (rank : 1508)	θ value	θ > 10 (rank : 2976)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1151	Shared Neighborhood Hits	446
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

RABE1_HUMAN
NC score	0.057391 (rank : 1509)	θ value	3.0926 (rank : 2212)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1104	Shared Neighborhood Hits	421
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

FLIP1_MOUSE
NC score	0.057390 (rank : 1510)	θ value	4.03905 (rank : 2281)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1176	Shared Neighborhood Hits	454
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

RBCC1_MOUSE
NC score	0.057367 (rank : 1511)	θ value	θ > 10 (rank : 3081)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1048	Shared Neighborhood Hits	404
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

CCD39_HUMAN
NC score	0.057314 (rank : 1512)	θ value	2.36792 (rank : 2021)
Query Neighborhood Hits	2923	Target Neighborhood Hits	868	Shared Neighborhood Hits	350
SwissProt Accessions	Q9UFE4	Gene names	CCDC39
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

CEP63_HUMAN
NC score	0.057307 (rank : 1513)	θ value	8.99809 (rank : 2749)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1005	Shared Neighborhood Hits	387
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

SWP70_HUMAN
NC score	0.057302 (rank : 1514)	θ value	θ > 10 (rank : 3107)
Query Neighborhood Hits	2923	Target Neighborhood Hits	973	Shared Neighborhood Hits	381
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

PEPL_HUMAN
NC score	0.057283 (rank : 1515)	θ value	θ > 10 (rank : 3062)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1141	Shared Neighborhood Hits	426
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

PLCB4_HUMAN
NC score	0.057268 (rank : 1516)	θ value	0.0113563 (rank : 1206)
Query Neighborhood Hits	2923	Target Neighborhood Hits	658	Shared Neighborhood Hits	326
SwissProt Accessions	Q15147, Q5JYS8, Q5JYT0, Q5JYT4, Q9BQW5, Q9BQW6, Q9BQW8, Q9UJQ2	Gene names	PLCB4
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-4) (PLC-beta-4).

TARA_MOUSE
NC score	0.057254 (rank : 1517)	θ value	θ > 10 (rank : 3110)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1133	Shared Neighborhood Hits	469
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

CCDC6_HUMAN
NC score	0.057212 (rank : 1518)	θ value	θ > 10 (rank : 2963)
Query Neighborhood Hits	2923	Target Neighborhood Hits	723	Shared Neighborhood Hits	348
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

GOGA5_MOUSE
NC score	0.057210 (rank : 1519)	θ value	θ > 10 (rank : 3000)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1434	Shared Neighborhood Hits	499
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

GRAP_HUMAN
NC score	0.057178 (rank : 1520)	θ value	θ > 10 (rank : 3005)
Query Neighborhood Hits	2923	Target Neighborhood Hits	307	Shared Neighborhood Hits	88
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

CD7_MOUSE
NC score	0.057157 (rank : 1521)	θ value	0.0193708 (rank : 1231)
Query Neighborhood Hits	2923	Target Neighborhood Hits	142	Shared Neighborhood Hits	87
SwissProt Accessions	P50283	Gene names	Cd7
Domain Architecture
Description	T-cell antigen CD7 precursor.

P85B_HUMAN
NC score	0.057156 (rank : 1522)	θ value	6.88961 (rank : 2665)
Query Neighborhood Hits	2923	Target Neighborhood Hits	543	Shared Neighborhood Hits	262
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

CEP35_HUMAN
NC score	0.057150 (rank : 1523)	θ value	2.36792 (rank : 2030)
Query Neighborhood Hits	2923	Target Neighborhood Hits	811	Shared Neighborhood Hits	383
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

TRIM9_MOUSE
NC score	0.057101 (rank : 1524)	θ value	0.00869519 (rank : 1195)
Query Neighborhood Hits	2923	Target Neighborhood Hits	274	Shared Neighborhood Hits	87
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

AZI1_MOUSE
NC score	0.057080 (rank : 1525)	θ value	2.36792 (rank : 2018)
Query Neighborhood Hits	2923	Target Neighborhood Hits	990	Shared Neighborhood Hits	396
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

SMC1A_MOUSE
NC score	0.057053 (rank : 1526)	θ value	θ > 10 (rank : 3100)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1384	Shared Neighborhood Hits	497
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

PTPRG_MOUSE
NC score	0.057046 (rank : 1527)	θ value	0.00298849 (rank : 1129)
Query Neighborhood Hits	2923	Target Neighborhood Hits	260	Shared Neighborhood Hits	108
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

CCHCR_MOUSE
NC score	0.056970 (rank : 1528)	θ value	θ > 10 (rank : 2965)
Query Neighborhood Hits	2923	Target Neighborhood Hits	932	Shared Neighborhood Hits	392
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

PTN23_MOUSE
NC score	0.056962 (rank : 1529)	θ value	8.99809 (rank : 2862)
Query Neighborhood Hits	2923	Target Neighborhood Hits	726	Shared Neighborhood Hits	339
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

BT3A1_HUMAN
NC score	0.056953 (rank : 1530)	θ value	0.0431538 (rank : 1281)
Query Neighborhood Hits	2923	Target Neighborhood Hits	229	Shared Neighborhood Hits	150
SwissProt Accessions	O00481, Q99420, Q9HCY1	Gene names	BTN3A1, BTF5
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A1 precursor (CD277 antigen).

EVPL_HUMAN
NC score	0.056951 (rank : 1531)	θ value	4.03905 (rank : 2280)
Query Neighborhood Hits	2923	Target Neighborhood Hits	895	Shared Neighborhood Hits	380
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

GOGA3_HUMAN
NC score	0.056917 (rank : 1532)	θ value	8.99809 (rank : 2788)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1317	Shared Neighborhood Hits	455
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

PACE1_MOUSE
NC score	0.056916 (rank : 1533)	θ value	θ > 10 (rank : 3059)
Query Neighborhood Hits	2923	Target Neighborhood Hits	92	Shared Neighborhood Hits	65
SwissProt Accessions	Q9DBQ7, Q6NY01, Q8BQC9, Q8BRJ1	Gene names	Scyl3, Pace1
Domain Architecture	No domain graphic available
Description	Protein-associating with the carboxyl-terminal domain of ezrin (Ezrin- binding protein PACE-1) (SCY1-like protein 3).

DGKK_HUMAN
NC score	0.056906 (rank : 1534)	θ value	θ > 10 (rank : 2987)
Query Neighborhood Hits	2923	Target Neighborhood Hits	378	Shared Neighborhood Hits	184
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

VAV2_HUMAN
NC score	0.056889 (rank : 1535)	θ value	θ > 10 (rank : 3121)
Query Neighborhood Hits	2923	Target Neighborhood Hits	453	Shared Neighborhood Hits	136
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

CCD91_MOUSE
NC score	0.056877 (rank : 1536)	θ value	1.81305 (rank : 1916)
Query Neighborhood Hits	2923	Target Neighborhood Hits	699	Shared Neighborhood Hits	321
SwissProt Accessions	Q9D8L5, Q8R3N8, Q9D9E8	Gene names	Ccdc91, Ggabp
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner).

NIN_MOUSE
NC score	0.056848 (rank : 1537)	θ value	0.47712 (rank : 1619)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1376	Shared Neighborhood Hits	440
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

VAV_MOUSE
NC score	0.056840 (rank : 1538)	θ value	θ > 10 (rank : 3126)
Query Neighborhood Hits	2923	Target Neighborhood Hits	430	Shared Neighborhood Hits	129
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

PCQAP_HUMAN
NC score	0.056793 (rank : 1539)	θ value	θ > 10 (rank : 3060)
Query Neighborhood Hits	2923	Target Neighborhood Hits	549	Shared Neighborhood Hits	288
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

CKAP4_MOUSE
NC score	0.056707 (rank : 1540)	θ value	0.00175202 (rank : 1101)
Query Neighborhood Hits	2923	Target Neighborhood Hits	596	Shared Neighborhood Hits	253
SwissProt Accessions	Q8BMK4, Q8BTK8, Q8R3F2	Gene names	Ckap4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

MYH9_HUMAN
NC score	0.056697 (rank : 1541)	θ value	0.0563607 (rank : 1322)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1762	Shared Neighborhood Hits	569
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYH9_MOUSE
NC score	0.056643 (rank : 1542)	θ value	0.0961366 (rank : 1374)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1829	Shared Neighborhood Hits	589
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

CT2NL_HUMAN
NC score	0.056597 (rank : 1543)	θ value	θ > 10 (rank : 2980)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1059	Shared Neighborhood Hits	433
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

CP135_HUMAN
NC score	0.056532 (rank : 1544)	θ value	θ > 10 (rank : 2979)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1290	Shared Neighborhood Hits	444
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

MYO5A_HUMAN
NC score	0.056390 (rank : 1545)	θ value	0.0148317 (rank : 1221)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1092	Shared Neighborhood Hits	433
SwissProt Accessions	Q9Y4I1, O60653, Q07902, Q16249, Q9UE30, Q9UE31	Gene names	MYO5A, MYH12
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin).

CNTFR_MOUSE
NC score	0.056316 (rank : 1546)	θ value	0.365318 (rank : 1542)
Query Neighborhood Hits	2923	Target Neighborhood Hits	74	Shared Neighborhood Hits	62
SwissProt Accessions	O88507, Q80T01	Gene names	Cntfr
Domain Architecture	No domain graphic available
Description	Ciliary neurotrophic factor receptor alpha precursor (CNTFR alpha).

PTN6_MOUSE
NC score	0.056298 (rank : 1547)	θ value	θ > 10 (rank : 3075)
Query Neighborhood Hits	2923	Target Neighborhood Hits	225	Shared Neighborhood Hits	81
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

IL18R_HUMAN
NC score	0.056264 (rank : 1548)	θ value	θ > 10 (rank : 3024)
Query Neighborhood Hits	2923	Target Neighborhood Hits	81	Shared Neighborhood Hits	48
SwissProt Accessions	Q13478	Gene names	IL18R1, IL1RRP
Domain Architecture
Description	Interleukin-18 receptor 1 precursor (IL1 receptor-related protein) (IL-1Rrp) (CDw218a antigen).

CNTFR_HUMAN
NC score	0.056223 (rank : 1549)	θ value	0.21417 (rank : 1449)
Query Neighborhood Hits	2923	Target Neighborhood Hits	66	Shared Neighborhood Hits	53
SwissProt Accessions	P26992	Gene names	CNTFR
Domain Architecture
Description	Ciliary neurotrophic factor receptor alpha precursor (CNTFR alpha).

EEA1_HUMAN
NC score	0.056216 (rank : 1550)	θ value	0.0193708 (rank : 1232)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1796	Shared Neighborhood Hits	558
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

CD3E_MOUSE
NC score	0.056172 (rank : 1551)	θ value	0.0148317 (rank : 1214)
Query Neighborhood Hits	2923	Target Neighborhood Hits	34	Shared Neighborhood Hits	24
SwissProt Accessions	P22646	Gene names	Cd3e
Domain Architecture
Description	T-cell surface glycoprotein CD3 epsilon chain precursor (T-cell surface antigen T3/Leu-4 epsilon chain).

MYH11_HUMAN
NC score	0.056117 (rank : 1552)	θ value	4.03905 (rank : 2319)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1806	Shared Neighborhood Hits	572
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

GRAP_MOUSE
NC score	0.056089 (rank : 1553)	θ value	θ > 10 (rank : 3006)
Query Neighborhood Hits	2923	Target Neighborhood Hits	309	Shared Neighborhood Hits	85
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

GOGA2_MOUSE
NC score	0.056076 (rank : 1554)	θ value	6.88961 (rank : 2610)
Query Neighborhood Hits	2923	Target Neighborhood Hits	944	Shared Neighborhood Hits	342
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

MD1L1_HUMAN
NC score	0.056045 (rank : 1555)	θ value	θ > 10 (rank : 3041)
Query Neighborhood Hits	2923	Target Neighborhood Hits	893	Shared Neighborhood Hits	360
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

ITSN2_MOUSE
NC score	0.056015 (rank : 1556)	θ value	θ > 10 (rank : 3032)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1371	Shared Neighborhood Hits	486
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

CK024_HUMAN
NC score	0.056002 (rank : 1557)	θ value	0.813845 (rank : 1712)
Query Neighborhood Hits	2923	Target Neighborhood Hits	408	Shared Neighborhood Hits	167
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

OGFR_MOUSE
NC score	0.055951 (rank : 1558)	θ value	1.29631e-06 (rank : 889)
Query Neighborhood Hits	2923	Target Neighborhood Hits	584	Shared Neighborhood Hits	208
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

LIPA2_MOUSE
NC score	0.055918 (rank : 1559)	θ value	0.0961366 (rank : 1369)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1282	Shared Neighborhood Hits	480
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

IGSF8_MOUSE
NC score	0.055901 (rank : 1560)	θ value	θ > 10 (rank : 3023)
Query Neighborhood Hits	2923	Target Neighborhood Hits	94	Shared Neighborhood Hits	59
SwissProt Accessions	Q8R366, Q8R0L7	Gene names	Igsf8, Ewi2, Kct4, Pgrl
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 8 precursor (CD81 partner 3) (Glu- Trp-Ile EWI motif-containing protein 2) (EWI-2) (Keratinocytes- associated transmembrane protein 4) (KCT-4) (Prostaglandin regulatory- like protein) (CD316 antigen).

MYH14_MOUSE
NC score	0.055783 (rank : 1561)	θ value	0.0193708 (rank : 1239)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1225	Shared Neighborhood Hits	431
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

CENPE_HUMAN
NC score	0.055703 (rank : 1562)	θ value	0.125558 (rank : 1386)
Query Neighborhood Hits	2923	Target Neighborhood Hits	2060	Shared Neighborhood Hits	631
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

OFD1_HUMAN
NC score	0.055697 (rank : 1563)	θ value	θ > 10 (rank : 3055)
Query Neighborhood Hits	2923	Target Neighborhood Hits	753	Shared Neighborhood Hits	341
SwissProt Accessions	O75665, O75666	Gene names	OFD1, CXorf5
Domain Architecture	No domain graphic available
Description	Oral-facial-digital syndrome 1 protein (Protein 71-7A).

BPAEA_MOUSE
NC score	0.055694 (rank : 1564)	θ value	0.47712 (rank : 1589)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1480	Shared Neighborhood Hits	515
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

SH24A_HUMAN
NC score	0.055636 (rank : 1565)	θ value	θ > 10 (rank : 3093)
Query Neighborhood Hits	2923	Target Neighborhood Hits	455	Shared Neighborhood Hits	241
SwissProt Accessions	Q9H788, Q5XKC1, Q6NXE9, Q86YM2, Q96C88, Q9H7F7	Gene names	SH2D4A, SH2A
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 4A (Protein SH(2)A).

PHLB2_MOUSE
NC score	0.055604 (rank : 1566)	θ value	8.99809 (rank : 2856)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1016	Shared Neighborhood Hits	416
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

CUTL1_MOUSE
NC score	0.055425 (rank : 1567)	θ value	0.21417 (rank : 1453)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1620	Shared Neighborhood Hits	538
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

PTN6_HUMAN
NC score	0.055369 (rank : 1568)	θ value	θ > 10 (rank : 3074)
Query Neighborhood Hits	2923	Target Neighborhood Hits	234	Shared Neighborhood Hits	87
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

RAPH1_HUMAN
NC score	0.055338 (rank : 1569)	θ value	4.03905 (rank : 2338)
Query Neighborhood Hits	2923	Target Neighborhood Hits	593	Shared Neighborhood Hits	271
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

C102B_HUMAN
NC score	0.055333 (rank : 1570)	θ value	0.0148317 (rank : 1211)
Query Neighborhood Hits	2923	Target Neighborhood Hits	542	Shared Neighborhood Hits	257
SwissProt Accessions	Q68D86, Q7Z467, Q8NDK7, Q9H5C1	Gene names	CCDC102B, C18orf14
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 102B.

PHLB2_HUMAN
NC score	0.055320 (rank : 1571)	θ value	1.38821 (rank : 1872)
Query Neighborhood Hits	2923	Target Neighborhood Hits	964	Shared Neighborhood Hits	402
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

CT2NL_MOUSE
NC score	0.055196 (rank : 1572)	θ value	θ > 10 (rank : 2981)
Query Neighborhood Hits	2923	Target Neighborhood Hits	902	Shared Neighborhood Hits	405
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

CYLN2_MOUSE
NC score	0.055177 (rank : 1573)	θ value	θ > 10 (rank : 2982)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1002	Shared Neighborhood Hits	388
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

MUC2_HUMAN
NC score	0.055155 (rank : 1574)	θ value	8.99809 (rank : 2836)
Query Neighborhood Hits	2923	Target Neighborhood Hits	906	Shared Neighborhood Hits	337
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

CHIO_MOUSE
NC score	0.055058 (rank : 1575)	θ value	θ > 10 (rank : 2975)
Query Neighborhood Hits	2923	Target Neighborhood Hits	130	Shared Neighborhood Hits	45
SwissProt Accessions	Q80XD1, Q9D9W2, Q9ER57	Gene names	Chn2, Arhgap3, Bch
Domain Architecture	No domain graphic available
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

VAV2_MOUSE
NC score	0.055028 (rank : 1576)	θ value	θ > 10 (rank : 3122)
Query Neighborhood Hits	2923	Target Neighborhood Hits	456	Shared Neighborhood Hits	135
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

AMOT_HUMAN
NC score	0.054975 (rank : 1577)	θ value	4.03905 (rank : 2248)
Query Neighborhood Hits	2923	Target Neighborhood Hits	712	Shared Neighborhood Hits	349
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

CNTRB_HUMAN
NC score	0.054973 (rank : 1578)	θ value	θ > 10 (rank : 2978)
Query Neighborhood Hits	2923	Target Neighborhood Hits	690	Shared Neighborhood Hits	300
SwissProt Accessions	Q8N137, Q331K3, Q69YV7, Q8NCB8, Q8WXV3, Q96CQ7, Q9C060	Gene names	CNTROB, LIP8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

CF152_HUMAN
NC score	0.054858 (rank : 1579)	θ value	8.99809 (rank : 2751)
Query Neighborhood Hits	2923	Target Neighborhood Hits	704	Shared Neighborhood Hits	329
SwissProt Accessions	Q86VQ0, Q9BWX7	Gene names	C6orf152
Domain Architecture	No domain graphic available
Description	Protein C6orf152.

CCD62_HUMAN
NC score	0.054840 (rank : 1580)	θ value	θ > 10 (rank : 2961)
Query Neighborhood Hits	2923	Target Neighborhood Hits	631	Shared Neighborhood Hits	290
SwissProt Accessions	Q6P9F0, Q6ZVF2, Q86VJ0, Q9BYZ5	Gene names	CCDC62
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 60 (Aaa-protein) (Protein TSP- NY).

EEA1_MOUSE
NC score	0.054830 (rank : 1581)	θ value	8.99809 (rank : 2773)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1637	Shared Neighborhood Hits	543
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

THOC2_HUMAN
NC score	0.054825 (rank : 1582)	θ value	0.00390308 (rank : 1142)
Query Neighborhood Hits	2923	Target Neighborhood Hits	337	Shared Neighborhood Hits	173
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

MYH8_HUMAN
NC score	0.054819 (rank : 1583)	θ value	0.0736092 (rank : 1347)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1610	Shared Neighborhood Hits	524
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

CUTL1_HUMAN
NC score	0.054731 (rank : 1584)	θ value	0.47712 (rank : 1601)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1574	Shared Neighborhood Hits	535
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

RRBP1_HUMAN
NC score	0.054711 (rank : 1585)	θ value	4.03905 (rank : 2346)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1306	Shared Neighborhood Hits	479
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

MYH1_HUMAN
NC score	0.054686 (rank : 1586)	θ value	0.0961366 (rank : 1371)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1478	Shared Neighborhood Hits	491
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

SMC3_MOUSE
NC score	0.054667 (rank : 1587)	θ value	3.0926 (rank : 2223)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1187	Shared Neighborhood Hits	439
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

MYH1_MOUSE
NC score	0.054632 (rank : 1588)	θ value	0.0961366 (rank : 1372)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1461	Shared Neighborhood Hits	484
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

LUZP1_MOUSE
NC score	0.054470 (rank : 1589)	θ value	θ > 10 (rank : 3036)
Query Neighborhood Hits	2923	Target Neighborhood Hits	940	Shared Neighborhood Hits	399
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

IWS1_MOUSE
NC score	0.054466 (rank : 1590)	θ value	0.00390308 (rank : 1138)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1258	Shared Neighborhood Hits	423
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MYH10_HUMAN
NC score	0.054446 (rank : 1591)	θ value	3.0926 (rank : 2193)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1620	Shared Neighborhood Hits	525
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

DGKQ_HUMAN
NC score	0.054430 (rank : 1592)	θ value	θ > 10 (rank : 2988)
Query Neighborhood Hits	2923	Target Neighborhood Hits	131	Shared Neighborhood Hits	42
SwissProt Accessions	P52824	Gene names	DGKQ, DAGK4
Domain Architecture
Description	Diacylglycerol kinase theta (EC 2.7.1.107) (Diglyceride kinase theta) (DGK-theta) (DAG kinase theta).

PACE1_HUMAN
NC score	0.054414 (rank : 1593)	θ value	θ > 10 (rank : 3058)
Query Neighborhood Hits	2923	Target Neighborhood Hits	74	Shared Neighborhood Hits	52
SwissProt Accessions	Q8IZE3, Q5THA6, Q5THA8, Q8IZN9, Q96C56, Q9UBK6	Gene names	SCYL3, PACE1
Domain Architecture	No domain graphic available
Description	Protein-associating with the carboxyl-terminal domain of ezrin (Ezrin- binding protein PACE-1) (SCY1-like protein 3).

SMC3_HUMAN
NC score	0.054407 (rank : 1594)	θ value	3.0926 (rank : 2222)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1186	Shared Neighborhood Hits	437
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

MBB1A_HUMAN
NC score	0.054405 (rank : 1595)	θ value	0.0330416 (rank : 1269)
Query Neighborhood Hits	2923	Target Neighborhood Hits	665	Shared Neighborhood Hits	269
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

MARCS_HUMAN
NC score	0.054338 (rank : 1596)	θ value	θ > 10 (rank : 3038)
Query Neighborhood Hits	2923	Target Neighborhood Hits	204	Shared Neighborhood Hits	101
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

MYH2_HUMAN
NC score	0.054333 (rank : 1597)	θ value	0.0431538 (rank : 1291)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1491	Shared Neighborhood Hits	478
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

PTN23_HUMAN
NC score	0.054331 (rank : 1598)	θ value	θ > 10 (rank : 3073)
Query Neighborhood Hits	2923	Target Neighborhood Hits	646	Shared Neighborhood Hits	303
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

SMC1A_HUMAN
NC score	0.054318 (rank : 1599)	θ value	θ > 10 (rank : 3099)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1346	Shared Neighborhood Hits	483
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

LIPA2_HUMAN
NC score	0.054310 (rank : 1600)	θ value	0.0961366 (rank : 1368)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1044	Shared Neighborhood Hits	403
SwissProt Accessions	O75334	Gene names	PPFIA2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

MYH3_HUMAN
NC score	0.054285 (rank : 1601)	θ value	1.06291 (rank : 1798)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1660	Shared Neighborhood Hits	528
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

ITSN2_HUMAN
NC score	0.054269 (rank : 1602)	θ value	θ > 10 (rank : 3031)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1173	Shared Neighborhood Hits	422
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

MYO5A_MOUSE
NC score	0.054259 (rank : 1603)	θ value	0.47712 (rank : 1618)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1117	Shared Neighborhood Hits	437
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

LIPA1_HUMAN
NC score	0.054213 (rank : 1604)	θ value	θ > 10 (rank : 3035)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1294	Shared Neighborhood Hits	472
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

DREB_HUMAN
NC score	0.054190 (rank : 1605)	θ value	1.38821 (rank : 1839)
Query Neighborhood Hits	2923	Target Neighborhood Hits	450	Shared Neighborhood Hits	254
SwissProt Accessions	Q16643	Gene names	DBN1
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

GOGA5_HUMAN
NC score	0.054189 (rank : 1606)	θ value	θ > 10 (rank : 2999)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1168	Shared Neighborhood Hits	431
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

GRB2_HUMAN
NC score	0.054142 (rank : 1607)	θ value	θ > 10 (rank : 3007)
Query Neighborhood Hits	2923	Target Neighborhood Hits	310	Shared Neighborhood Hits	82
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

RGS3_HUMAN
NC score	0.054131 (rank : 1608)	θ value	2.44474e-05 (rank : 959)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1375	Shared Neighborhood Hits	401
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

GRB2_MOUSE
NC score	0.054118 (rank : 1609)	θ value	θ > 10 (rank : 3008)
Query Neighborhood Hits	2923	Target Neighborhood Hits	312	Shared Neighborhood Hits	82
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

MYH10_MOUSE
NC score	0.054104 (rank : 1610)	θ value	4.03905 (rank : 2318)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1612	Shared Neighborhood Hits	531
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

KMHN1_MOUSE
NC score	0.054095 (rank : 1611)	θ value	θ > 10 (rank : 3034)
Query Neighborhood Hits	2923	Target Neighborhood Hits	949	Shared Neighborhood Hits	383
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

P85B_MOUSE
NC score	0.054062 (rank : 1612)	θ value	θ > 10 (rank : 3057)
Query Neighborhood Hits	2923	Target Neighborhood Hits	519	Shared Neighborhood Hits	246
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

MYH8_MOUSE
NC score	0.054040 (rank : 1613)	θ value	0.0961366 (rank : 1373)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1600	Shared Neighborhood Hits	518
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

TUFT1_HUMAN
NC score	0.054019 (rank : 1614)	θ value	0.47712 (rank : 1643)
Query Neighborhood Hits	2923	Target Neighborhood Hits	686	Shared Neighborhood Hits	302
SwissProt Accessions	Q9NNX1, Q5T384, Q5T385, Q9BU28, Q9H5L1	Gene names	TUFT1
Domain Architecture	No domain graphic available
Description	Tuftelin.

BLNK_MOUSE
NC score	0.053985 (rank : 1615)	θ value	0.163984 (rank : 1407)
Query Neighborhood Hits	2923	Target Neighborhood Hits	296	Shared Neighborhood Hits	141
SwissProt Accessions	Q9QUN3, O88504	Gene names	Blnk, Bash, Ly57, Slp65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65) (Lymphocyte antigen 57).

IFT74_HUMAN
NC score	0.053971 (rank : 1616)	θ value	6.88961 (rank : 2623)
Query Neighborhood Hits	2923	Target Neighborhood Hits	949	Shared Neighborhood Hits	370
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

HIP1R_MOUSE
NC score	0.053961 (rank : 1617)	θ value	θ > 10 (rank : 3017)
Query Neighborhood Hits	2923	Target Neighborhood Hits	959	Shared Neighborhood Hits	392
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

TIMD1_HUMAN
NC score	0.053944 (rank : 1618)	θ value	θ > 10 (rank : 3116)
Query Neighborhood Hits	2923	Target Neighborhood Hits	155	Shared Neighborhood Hits	101
SwissProt Accessions	Q96D42, O43656	Gene names	HAVCR1, TIM1, TIMD1
Domain Architecture	No domain graphic available
Description	Hepatitis A virus cellular receptor 1 precursor (HAVcr-1) (T cell immunoglobulin and mucin domain-containing protein 1) (TIMD-1) (T cell membrane protein 1) (TIM-1) (TIM).

RASF1_HUMAN
NC score	0.053885 (rank : 1619)	θ value	θ > 10 (rank : 3079)
Query Neighborhood Hits	2923	Target Neighborhood Hits	62	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NS23, O14571, O60539, O60710, Q9HB04, Q9HB18, Q9NS22, Q9UND4, Q9UND5	Gene names	RASSF1, RDA32
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 1.

MYH6_MOUSE
NC score	0.053832 (rank : 1620)	θ value	2.36792 (rank : 2079)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1501	Shared Neighborhood Hits	488
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

TAU_MOUSE
NC score	0.053779 (rank : 1621)	θ value	6.88961 (rank : 2697)
Query Neighborhood Hits	2923	Target Neighborhood Hits	502	Shared Neighborhood Hits	195
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

NCOR2_MOUSE
NC score	0.053758 (rank : 1622)	θ value	1.06291 (rank : 1800)
Query Neighborhood Hits	2923	Target Neighborhood Hits	790	Shared Neighborhood Hits	374
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

EVPL_MOUSE
NC score	0.053736 (rank : 1623)	θ value	0.47712 (rank : 1603)
Query Neighborhood Hits	2923	Target Neighborhood Hits	952	Shared Neighborhood Hits	363
SwissProt Accessions	Q9D952	Gene names	Evpl
Domain Architecture
Description	Envoplakin (p210) (210 kDa cornified envelope precursor protein).

GRAP2_HUMAN
NC score	0.053696 (rank : 1624)	θ value	θ > 10 (rank : 3003)
Query Neighborhood Hits	2923	Target Neighborhood Hits	304	Shared Neighborhood Hits	81
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

MYH7_HUMAN
NC score	0.053649 (rank : 1625)	θ value	2.36792 (rank : 2080)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1559	Shared Neighborhood Hits	493
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

LAMA2_MOUSE
NC score	0.053552 (rank : 1626)	θ value	8.99809 (rank : 2819)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1198	Shared Neighborhood Hits	381
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

MYO5C_HUMAN
NC score	0.053529 (rank : 1627)	θ value	8.99809 (rank : 2838)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1206	Shared Neighborhood Hits	440
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

PRPE_HUMAN
NC score	0.053525 (rank : 1628)	θ value	3.0926 (rank : 2211)
Query Neighborhood Hits	2923	Target Neighborhood Hits	44	Shared Neighborhood Hits	21
SwissProt Accessions	P02811	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide P-E (IB-9).

RBBP6_HUMAN
NC score	0.053415 (rank : 1629)	θ value	1.06291 (rank : 1806)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1135	Shared Neighborhood Hits	448
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

CJ118_HUMAN
NC score	0.053357 (rank : 1630)	θ value	0.21417 (rank : 1448)
Query Neighborhood Hits	2923	Target Neighborhood Hits	937	Shared Neighborhood Hits	352
SwissProt Accessions	Q7Z3E2, Q2M2V6, Q6NS91, Q7RTP1, Q8N117, Q8N3G3, Q8N6C2, Q9NWA3	Gene names	C10orf118
Domain Architecture	No domain graphic available
Description	Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2).

ERC2_MOUSE
NC score	0.053289 (rank : 1631)	θ value	8.99809 (rank : 2779)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1166	Shared Neighborhood Hits	416
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

CF182_MOUSE
NC score	0.053260 (rank : 1632)	θ value	1.81305 (rank : 1918)
Query Neighborhood Hits	2923	Target Neighborhood Hits	551	Shared Neighborhood Hits	271
SwissProt Accessions	Q8VDS7, Q9CZE0, Q9D5A1	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf182 homolog.

SM1L2_HUMAN
NC score	0.053161 (rank : 1633)	θ value	θ > 10 (rank : 3098)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1019	Shared Neighborhood Hits	407
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

ALEX_HUMAN
NC score	0.053160 (rank : 1634)	θ value	θ > 10 (rank : 2936)
Query Neighborhood Hits	2923	Target Neighborhood Hits	361	Shared Neighborhood Hits	167
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

GCC1_HUMAN
NC score	0.053141 (rank : 1635)	θ value	θ > 10 (rank : 2997)
Query Neighborhood Hits	2923	Target Neighborhood Hits	887	Shared Neighborhood Hits	347
SwissProt Accessions	Q96CN9, Q9H6N7	Gene names	GCC1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

GOG8A_HUMAN
NC score	0.053075 (rank : 1636)	θ value	5.27518 (rank : 2431)
Query Neighborhood Hits	2923	Target Neighborhood Hits	635	Shared Neighborhood Hits	298
SwissProt Accessions	Q9NZW0, O94937, Q9NZG8, Q9NZW3	Gene names	GOLGA8A, KIAA0855
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 8A/B (Golgi autoantigen golgin-67) (88 kDa Golgi protein) (Gm88 autoantigen).

KMHN1_HUMAN
NC score	0.053033 (rank : 1637)	θ value	θ > 10 (rank : 3033)
Query Neighborhood Hits	2923	Target Neighborhood Hits	950	Shared Neighborhood Hits	368
SwissProt Accessions	Q8TBZ0, Q86YI9, Q8N7W0	Gene names	KMHN1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1.

NPBL_MOUSE
NC score	0.052891 (rank : 1638)	θ value	0.62314 (rank : 1682)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1041	Shared Neighborhood Hits	397
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

WASIP_MOUSE
NC score	0.052887 (rank : 1639)	θ value	θ > 10 (rank : 3128)
Query Neighborhood Hits	2923	Target Neighborhood Hits	392	Shared Neighborhood Hits	198
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

AMGO1_MOUSE
NC score	0.052883 (rank : 1640)	θ value	1.38821 (rank : 1819)
Query Neighborhood Hits	2923	Target Neighborhood Hits	325	Shared Neighborhood Hits	115
SwissProt Accessions	Q80ZD8, Q69ZQ0, Q8R5D4, Q921U9	Gene names	Amigo1, Ali2, Amigo, Kiaa1163
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 1 precursor (AMIGO-1) (Alivin-2).

MAP2_HUMAN
NC score	0.052883 (rank : 1641)	θ value	0.000121331 (rank : 1011)
Query Neighborhood Hits	2923	Target Neighborhood Hits	348	Shared Neighborhood Hits	179
SwissProt Accessions	P11137, Q99975, Q99976	Gene names	MAP2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2) (MAP-2).

ALEX_MOUSE
NC score	0.052877 (rank : 1642)	θ value	1.06291 (rank : 1765)
Query Neighborhood Hits	2923	Target Neighborhood Hits	197	Shared Neighborhood Hits	103
SwissProt Accessions	Q6R0H6, Q8BIR3	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

CR034_HUMAN
NC score	0.052708 (rank : 1643)	θ value	0.47712 (rank : 1600)
Query Neighborhood Hits	2923	Target Neighborhood Hits	538	Shared Neighborhood Hits	247
SwissProt Accessions	Q5BJE1, Q6ZP67, Q6ZU20	Gene names	C18orf34
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34.

CKAP4_HUMAN
NC score	0.052675 (rank : 1644)	θ value	0.0961366 (rank : 1360)
Query Neighborhood Hits	2923	Target Neighborhood Hits	592	Shared Neighborhood Hits	262
SwissProt Accessions	Q07065, Q504S5, Q53ES6	Gene names	CKAP4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

SH21B_MOUSE
NC score	0.052614 (rank : 1645)	θ value	θ > 10 (rank : 3092)
Query Neighborhood Hits	2923	Target Neighborhood Hits	101	Shared Neighborhood Hits	44
SwissProt Accessions	O35324, Q8C268	Gene names	Sh2d1b, Eat2, Sh2d1b1
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

CN145_MOUSE
NC score	0.052553 (rank : 1646)	θ value	θ > 10 (rank : 2977)
Query Neighborhood Hits	2923	Target Neighborhood Hits	916	Shared Neighborhood Hits	361
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

MYH6_HUMAN
NC score	0.052552 (rank : 1647)	θ value	2.36792 (rank : 2078)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1426	Shared Neighborhood Hits	467
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH4_MOUSE
NC score	0.052547 (rank : 1648)	θ value	0.125558 (rank : 1395)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1476	Shared Neighborhood Hits	479
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

GRAP2_MOUSE
NC score	0.052520 (rank : 1649)	θ value	θ > 10 (rank : 3004)
Query Neighborhood Hits	2923	Target Neighborhood Hits	297	Shared Neighborhood Hits	79
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

SMC2_MOUSE
NC score	0.052456 (rank : 1650)	θ value	0.163984 (rank : 1434)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1131	Shared Neighborhood Hits	436
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

MYH4_HUMAN
NC score	0.052454 (rank : 1651)	θ value	0.125558 (rank : 1394)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1377	Shared Neighborhood Hits	457
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

MYH13_HUMAN
NC score	0.052450 (rank : 1652)	θ value	4.03905 (rank : 2320)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1504	Shared Neighborhood Hits	467
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

CARD9_HUMAN
NC score	0.052421 (rank : 1653)	θ value	θ > 10 (rank : 2957)
Query Neighborhood Hits	2923	Target Neighborhood Hits	602	Shared Neighborhood Hits	284
SwissProt Accessions	Q9H257, Q5SXM6, Q9H854	Gene names	CARD9
Domain Architecture
Description	Caspase recruitment domain-containing protein 9 (hCARD9).

SLAF6_HUMAN
NC score	0.052272 (rank : 1654)	θ value	0.00869519 (rank : 1190)
Query Neighborhood Hits	2923	Target Neighborhood Hits	62	Shared Neighborhood Hits	56
SwissProt Accessions	Q96DU3, Q5TAT3, Q96DV0	Gene names	SLAMF6, KALI
Domain Architecture	No domain graphic available
Description	SLAM family member 6 precursor (NK-T-B-antigen) (NTB-A) (Activating NK receptor).

TXLNA_HUMAN
NC score	0.052270 (rank : 1655)	θ value	1.81305 (rank : 2005)
Query Neighborhood Hits	2923	Target Neighborhood Hits	982	Shared Neighborhood Hits	398
SwissProt Accessions	P40222, Q66K62, Q86T54, Q86T85, Q86T86, Q86Y86, Q86YW3, Q8N2Y3	Gene names	TXLNA, TXLN
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

NFM_HUMAN
NC score	0.052249 (rank : 1656)	θ value	7.59969e-07 (rank : 871)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1328	Shared Neighborhood Hits	573
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

DREB_MOUSE
NC score	0.052239 (rank : 1657)	θ value	5.27518 (rank : 2413)
Query Neighborhood Hits	2923	Target Neighborhood Hits	446	Shared Neighborhood Hits	249
SwissProt Accessions	Q9QXS6, Q922X1, Q9QXS5	Gene names	Dbn1, Drba
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

MARCS_MOUSE
NC score	0.052223 (rank : 1658)	θ value	θ > 10 (rank : 3039)
Query Neighborhood Hits	2923	Target Neighborhood Hits	227	Shared Neighborhood Hits	112
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

CEA19_HUMAN
NC score	0.052193 (rank : 1659)	θ value	θ > 10 (rank : 2967)
Query Neighborhood Hits	2923	Target Neighborhood Hits	36	Shared Neighborhood Hits	26
SwissProt Accessions	Q7Z692, Q7Z693	Gene names	CEACAM19, CEAL1
Domain Architecture	No domain graphic available
Description	Carcinoembryonic antigen-related cell adhesion molecule 19 precursor (Carcinoembryonic antigen-like 1).

ERC2_HUMAN
NC score	0.052180 (rank : 1660)	θ value	1.38821 (rank : 1843)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1156	Shared Neighborhood Hits	410
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

CCHCR_HUMAN
NC score	0.052045 (rank : 1661)	θ value	θ > 10 (rank : 2964)
Query Neighborhood Hits	2923	Target Neighborhood Hits	717	Shared Neighborhood Hits	307
SwissProt Accessions	Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2	Gene names	CCHCR1, C6orf18, HCR
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8).

BLNK_HUMAN
NC score	0.051973 (rank : 1662)	θ value	0.0330416 (rank : 1262)
Query Neighborhood Hits	2923	Target Neighborhood Hits	228	Shared Neighborhood Hits	107
SwissProt Accessions	Q8WV28, O75498, O75499	Gene names	BLNK, BASH, SLP65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (SLP-65).

HAPIP_HUMAN
NC score	0.051923 (rank : 1663)	θ value	θ > 10 (rank : 3016)
Query Neighborhood Hits	2923	Target Neighborhood Hits	350	Shared Neighborhood Hits	148
SwissProt Accessions	O60229	Gene names	HAPIP, DUO
Domain Architecture
Description	Huntingtin-associated protein-interacting protein (Protein Duo).

ANR26_MOUSE
NC score	0.051817 (rank : 1664)	θ value	0.62314 (rank : 1648)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1554	Shared Neighborhood Hits	478
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

RTN4_HUMAN
NC score	0.051773 (rank : 1665)	θ value	5.44631e-05 (rank : 985)
Query Neighborhood Hits	2923	Target Neighborhood Hits	357	Shared Neighborhood Hits	186
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

GP125_MOUSE
NC score	0.051751 (rank : 1666)	θ value	0.21417 (rank : 1466)
Query Neighborhood Hits	2923	Target Neighborhood Hits	329	Shared Neighborhood Hits	98
SwissProt Accessions	Q7TT36, Q6PE67, Q8VE71	Gene names	Gpr125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

RFIP3_HUMAN
NC score	0.051748 (rank : 1667)	θ value	θ > 10 (rank : 3084)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1055	Shared Neighborhood Hits	415
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

PLEC1_HUMAN
NC score	0.051695 (rank : 1668)	θ value	0.00869519 (rank : 1187)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1326	Shared Neighborhood Hits	463
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

MBD6_HUMAN
NC score	0.051599 (rank : 1669)	θ value	θ > 10 (rank : 3040)
Query Neighborhood Hits	2923	Target Neighborhood Hits	349	Shared Neighborhood Hits	156
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

CCD45_HUMAN
NC score	0.051597 (rank : 1670)	θ value	θ > 10 (rank : 2960)
Query Neighborhood Hits	2923	Target Neighborhood Hits	525	Shared Neighborhood Hits	285
SwissProt Accessions	Q96GE4, Q96M81	Gene names	CCDC45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

NCK1_HUMAN
NC score	0.051514 (rank : 1671)	θ value	θ > 10 (rank : 3051)
Query Neighborhood Hits	2923	Target Neighborhood Hits	312	Shared Neighborhood Hits	83
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

APXL_HUMAN
NC score	0.051500 (rank : 1672)	θ value	0.0736092 (rank : 1325)
Query Neighborhood Hits	2923	Target Neighborhood Hits	553	Shared Neighborhood Hits	228
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

ASPP1_MOUSE
NC score	0.051436 (rank : 1673)	θ value	0.00175202 (rank : 1100)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1244	Shared Neighborhood Hits	459
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

PELP1_HUMAN
NC score	0.051416 (rank : 1674)	θ value	1.81305 (rank : 1968)
Query Neighborhood Hits	2923	Target Neighborhood Hits	596	Shared Neighborhood Hits	303
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

YLPM1_MOUSE
NC score	0.051352 (rank : 1675)	θ value	θ > 10 (rank : 3131)
Query Neighborhood Hits	2923	Target Neighborhood Hits	505	Shared Neighborhood Hits	240
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

IFT74_MOUSE
NC score	0.051297 (rank : 1676)	θ value	θ > 10 (rank : 3020)
Query Neighborhood Hits	2923	Target Neighborhood Hits	939	Shared Neighborhood Hits	362
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

TRAK1_HUMAN
NC score	0.051288 (rank : 1677)	θ value	0.0736092 (rank : 1354)
Query Neighborhood Hits	2923	Target Neighborhood Hits	660	Shared Neighborhood Hits	300
SwissProt Accessions	Q9UPV9, Q96B69	Gene names	TRAK1, KIAA1042, OIP106
Domain Architecture	No domain graphic available
Description	Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase- interacting protein).

PAF49_HUMAN
NC score	0.051240 (rank : 1678)	θ value	0.0431538 (rank : 1292)
Query Neighborhood Hits	2923	Target Neighborhood Hits	169	Shared Neighborhood Hits	93
SwissProt Accessions	O15446, Q32N11, Q7Z5U2, Q9UPF6	Gene names	CD3EAP, ASE1, CAST, PAF49
Domain Architecture	No domain graphic available
Description	RNA polymerase I-associated factor PAF49 (Anti-sense to ERCC-1 protein) (ASE-1) (CD3-epsilon-associated protein) (CD3E-associated protein) (CAST).

PTPRZ_HUMAN
NC score	0.051152 (rank : 1679)	θ value	θ > 10 (rank : 3076)
Query Neighborhood Hits	2923	Target Neighborhood Hits	255	Shared Neighborhood Hits	91
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

MOES_MOUSE
NC score	0.051140 (rank : 1680)	θ value	0.000121331 (rank : 1013)
Query Neighborhood Hits	2923	Target Neighborhood Hits	923	Shared Neighborhood Hits	369
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

NEMO_MOUSE
NC score	0.051086 (rank : 1681)	θ value	θ > 10 (rank : 3054)
Query Neighborhood Hits	2923	Target Neighborhood Hits	658	Shared Neighborhood Hits	293
SwissProt Accessions	O88522	Gene names	Ikbkg, Nemo
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (mFIP-3).

HOOK3_HUMAN
NC score	0.050993 (rank : 1682)	θ value	0.0961366 (rank : 1363)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1070	Shared Neighborhood Hits	394
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

SAS6_HUMAN
NC score	0.050840 (rank : 1683)	θ value	8.99809 (rank : 2872)
Query Neighborhood Hits	2923	Target Neighborhood Hits	791	Shared Neighborhood Hits	318
SwissProt Accessions	Q6UVJ0, Q8N3K0	Gene names	SASS6, SAS6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog (HsSAS-6).

SIGIR_HUMAN
NC score	0.050781 (rank : 1684)	θ value	1.06291 (rank : 1812)
Query Neighborhood Hits	2923	Target Neighborhood Hits	53	Shared Neighborhood Hits	31
SwissProt Accessions	Q6IA17, Q3KQY2, Q6UXI3, Q9H733	Gene names	SIGIRR
Domain Architecture	No domain graphic available
Description	Single Ig IL-1-related receptor (Single Ig IL-1R-related molecule) (Single immunoglobulin domain-containing IL1R-related protein) (Toll/interleukin-1 receptor 8) (TIR8).

TUFT1_MOUSE
NC score	0.050750 (rank : 1685)	θ value	0.163984 (rank : 1437)
Query Neighborhood Hits	2923	Target Neighborhood Hits	732	Shared Neighborhood Hits	305
SwissProt Accessions	O08970	Gene names	Tuft1
Domain Architecture
Description	Tuftelin.

UACA_MOUSE
NC score	0.050726 (rank : 1686)	θ value	5.27518 (rank : 2527)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1620	Shared Neighborhood Hits	492
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

ASPP2_HUMAN
NC score	0.050659 (rank : 1687)	θ value	5.27518 (rank : 2386)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1156	Shared Neighborhood Hits	429
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

REN3B_HUMAN
NC score	0.050626 (rank : 1688)	θ value	θ > 10 (rank : 3083)
Query Neighborhood Hits	2923	Target Neighborhood Hits	412	Shared Neighborhood Hits	220
SwissProt Accessions	Q9BZI7, Q9H1J0	Gene names	UPF3B, RENT3B, UPF3X
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3B (Nonsense mRNA reducing factor 3B) (Up-frameshift suppressor 3 homolog B) (hUpf3B) (hUpf3p-X).

GCC1_MOUSE
NC score	0.050621 (rank : 1689)	θ value	θ > 10 (rank : 2998)
Query Neighborhood Hits	2923	Target Neighborhood Hits	777	Shared Neighborhood Hits	328
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

CR034_MOUSE
NC score	0.050602 (rank : 1690)	θ value	3.0926 (rank : 2149)
Query Neighborhood Hits	2923	Target Neighborhood Hits	643	Shared Neighborhood Hits	289
SwissProt Accessions	Q8CDV0	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34 homolog.

MYO9B_HUMAN
NC score	0.050564 (rank : 1691)	θ value	0.000270298 (rank : 1039)
Query Neighborhood Hits	2923	Target Neighborhood Hits	641	Shared Neighborhood Hits	268
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

MOES_HUMAN
NC score	0.050558 (rank : 1692)	θ value	0.000121331 (rank : 1012)
Query Neighborhood Hits	2923	Target Neighborhood Hits	892	Shared Neighborhood Hits	368
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

ZWINT_MOUSE
NC score	0.050556 (rank : 1693)	θ value	6.88961 (rank : 2719)
Query Neighborhood Hits	2923	Target Neighborhood Hits	497	Shared Neighborhood Hits	258
SwissProt Accessions	Q9CQU5, Q3UYT8, Q91VI4, Q9D0W9	Gene names	Zwint, D10Ertd749e
Domain Architecture	No domain graphic available
Description	ZW10 interactor (ZW10-interacting protein 1) (Zwint-1).

CCD13_HUMAN
NC score	0.050543 (rank : 1694)	θ value	θ > 10 (rank : 2958)
Query Neighborhood Hits	2923	Target Neighborhood Hits	721	Shared Neighborhood Hits	298
SwissProt Accessions	Q8IYE1	Gene names	CCDC13
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 13.

BPTF_HUMAN
NC score	0.050471 (rank : 1695)	θ value	0.00390308 (rank : 1136)
Query Neighborhood Hits	2923	Target Neighborhood Hits	786	Shared Neighborhood Hits	343
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

NCOA6_MOUSE
NC score	0.050416 (rank : 1696)	θ value	3.0926 (rank : 2196)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1076	Shared Neighborhood Hits	371
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

CEP55_MOUSE
NC score	0.050394 (rank : 1697)	θ value	θ > 10 (rank : 2970)
Query Neighborhood Hits	2923	Target Neighborhood Hits	693	Shared Neighborhood Hits	317
SwissProt Accessions	Q8BT07, Q8C2J0, Q8K2I8, Q8R2Y4, Q9DBZ8	Gene names	Cep55
Domain Architecture	No domain graphic available
Description	Centrosome protein 55.

NCK2_HUMAN
NC score	0.050381 (rank : 1698)	θ value	θ > 10 (rank : 3052)
Query Neighborhood Hits	2923	Target Neighborhood Hits	310	Shared Neighborhood Hits	81
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

NAF1_HUMAN
NC score	0.050359 (rank : 1699)	θ value	θ > 10 (rank : 3049)
Query Neighborhood Hits	2923	Target Neighborhood Hits	937	Shared Neighborhood Hits	396
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

TXLNB_HUMAN
NC score	0.050302 (rank : 1700)	θ value	θ > 10 (rank : 3118)
Query Neighborhood Hits	2923	Target Neighborhood Hits	912	Shared Neighborhood Hits	382
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

NAF1_MOUSE
NC score	0.050152 (rank : 1701)	θ value	θ > 10 (rank : 3050)
Query Neighborhood Hits	2923	Target Neighborhood Hits	852	Shared Neighborhood Hits	380
SwissProt Accessions	Q9WUU8, Q922A9, Q922F7, Q9EPP8, Q9R0X3	Gene names	Tnip1, Abin, Naf1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (A20- binding inhibitor of NF-kappa-B activation) (ABIN) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).

MOG_MOUSE
NC score	0.050117 (rank : 1702)	θ value	0.47712 (rank : 1615)
Query Neighborhood Hits	2923	Target Neighborhood Hits	102	Shared Neighborhood Hits	84
SwissProt Accessions	Q61885, P70364, Q62003	Gene names	Mog
Domain Architecture
Description	Myelin-oligodendrocyte glycoprotein precursor.

GP125_HUMAN
NC score	0.050062 (rank : 1703)	θ value	0.21417 (rank : 1465)
Query Neighborhood Hits	2923	Target Neighborhood Hits	327	Shared Neighborhood Hits	93
SwissProt Accessions	Q8IWK6, Q6UXK9, Q86SQ5, Q8TC55	Gene names	GPR125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

SFRIP_HUMAN
NC score	0.050030 (rank : 1704)	θ value	5.27518 (rank : 2511)
Query Neighborhood Hits	2923	Target Neighborhood Hits	530	Shared Neighborhood Hits	227
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

RSF1_HUMAN
NC score	0.050029 (rank : 1705)	θ value	1.81305 (rank : 1978)
Query Neighborhood Hits	2923	Target Neighborhood Hits	539	Shared Neighborhood Hits	269
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

MACF4_HUMAN
NC score	0.050024 (rank : 1706)	θ value	0.0563607 (rank : 1317)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1321	Shared Neighborhood Hits	429
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

SPR1A_MOUSE
NC score	0.049956 (rank : 1707)	θ value	9.29e-05 (rank : 1006)
Query Neighborhood Hits	2923	Target Neighborhood Hits	343	Shared Neighborhood Hits	119
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

CJ068_HUMAN
NC score	0.049925 (rank : 1708)	θ value	2.36792 (rank : 2032)
Query Neighborhood Hits	2923	Target Neighborhood Hits	316	Shared Neighborhood Hits	177
SwissProt Accessions	Q9H943, Q8N7T7	Gene names	C10orf68
Domain Architecture	No domain graphic available
Description	Protein C10orf68.

CCD27_MOUSE
NC score	0.049906 (rank : 1709)	θ value	3.0926 (rank : 2141)
Query Neighborhood Hits	2923	Target Neighborhood Hits	461	Shared Neighborhood Hits	239
SwissProt Accessions	Q3V036	Gene names	Ccdc27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

SLAF1_MOUSE
NC score	0.049782 (rank : 1710)	θ value	0.125558 (rank : 1401)
Query Neighborhood Hits	2923	Target Neighborhood Hits	60	Shared Neighborhood Hits	49
SwissProt Accessions	Q9QUM4, Q9QXZ3	Gene names	Slamf1, Slam
Domain Architecture
Description	Signaling lymphocytic activation molecule precursor (CD150 antigen).

MYH14_HUMAN
NC score	0.049702 (rank : 1711)	θ value	1.06291 (rank : 1797)
Query Neighborhood Hits	2923	Target Neighborhood Hits	995	Shared Neighborhood Hits	345
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

CO039_MOUSE
NC score	0.049671 (rank : 1712)	θ value	0.00228821 (rank : 1113)
Query Neighborhood Hits	2923	Target Neighborhood Hits	445	Shared Neighborhood Hits	196
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

GOGA2_HUMAN
NC score	0.049499 (rank : 1713)	θ value	5.27518 (rank : 2432)
Query Neighborhood Hits	2923	Target Neighborhood Hits	856	Shared Neighborhood Hits	333
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

BICD2_HUMAN
NC score	0.049479 (rank : 1714)	θ value	8.99809 (rank : 2736)
Query Neighborhood Hits	2923	Target Neighborhood Hits	856	Shared Neighborhood Hits	345
SwissProt Accessions	Q8TD16, O75181, Q5TBQ2, Q5TBQ3, Q96LH2, Q9BT84, Q9H561	Gene names	BICD2, KIAA0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

EP300_HUMAN
NC score	0.049365 (rank : 1715)	θ value	6.88961 (rank : 2592)
Query Neighborhood Hits	2923	Target Neighborhood Hits	821	Shared Neighborhood Hits	332
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

LRC27_HUMAN
NC score	0.049088 (rank : 1716)	θ value	0.279714 (rank : 1512)
Query Neighborhood Hits	2923	Target Neighborhood Hits	710	Shared Neighborhood Hits	295
SwissProt Accessions	Q9C0I9, Q5SZH6, Q5SZH8, Q5SZH9, Q86XT5, Q8N7C8, Q8NA21	Gene names	LRRC27, KIAA1674
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 27.

MUC5B_HUMAN
NC score	0.049083 (rank : 1717)	θ value	0.813845 (rank : 1735)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1020	Shared Neighborhood Hits	313
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

BICD1_HUMAN
NC score	0.048920 (rank : 1718)	θ value	3.0926 (rank : 2131)
Query Neighborhood Hits	2923	Target Neighborhood Hits	844	Shared Neighborhood Hits	350
SwissProt Accessions	Q96G01, O43892, O43893	Gene names	BICD1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

ZN318_MOUSE
NC score	0.048881 (rank : 1719)	θ value	0.0736092 (rank : 1356)
Query Neighborhood Hits	2923	Target Neighborhood Hits	642	Shared Neighborhood Hits	301
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

RGNEF_MOUSE
NC score	0.048793 (rank : 1720)	θ value	8.99809 (rank : 2866)
Query Neighborhood Hits	2923	Target Neighborhood Hits	641	Shared Neighborhood Hits	291
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

K1543_HUMAN
NC score	0.048750 (rank : 1721)	θ value	0.0193708 (rank : 1237)
Query Neighborhood Hits	2923	Target Neighborhood Hits	435	Shared Neighborhood Hits	175
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

TPM1_MOUSE
NC score	0.048709 (rank : 1722)	θ value	0.365318 (rank : 1572)
Query Neighborhood Hits	2923	Target Neighborhood Hits	729	Shared Neighborhood Hits	313
SwissProt Accessions	P58771, P02558, P19354, P46902, P99034	Gene names	Tpm1, Tpm-1, Tpma
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

UACA_HUMAN
NC score	0.048650 (rank : 1723)	θ value	0.0193708 (rank : 1248)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1622	Shared Neighborhood Hits	469
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

IL12B_MOUSE
NC score	0.048648 (rank : 1724)	θ value	0.0961366 (rank : 1366)
Query Neighborhood Hits	2923	Target Neighborhood Hits	43	Shared Neighborhood Hits	41
SwissProt Accessions	P43432, Q9QUM1	Gene names	Il12b
Domain Architecture
Description	Interleukin-12 beta chain precursor (IL-12B) (IL-12 p40) (Cytotoxic lymphocyte maturation factor 40 kDa subunit) (CLMF p40).

NASP_HUMAN
NC score	0.048645 (rank : 1725)	θ value	4.03905 (rank : 2322)
Query Neighborhood Hits	2923	Target Neighborhood Hits	709	Shared Neighborhood Hits	300
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

SMC4_MOUSE
NC score	0.048631 (rank : 1726)	θ value	0.0330416 (rank : 1275)
Query Neighborhood Hits	2923	Target Neighborhood Hits	830	Shared Neighborhood Hits	334
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

CO039_HUMAN
NC score	0.048617 (rank : 1727)	θ value	0.00665767 (rank : 1162)
Query Neighborhood Hits	2923	Target Neighborhood Hits	264	Shared Neighborhood Hits	119
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

MAP2_MOUSE
NC score	0.048501 (rank : 1728)	θ value	0.0563607 (rank : 1318)
Query Neighborhood Hits	2923	Target Neighborhood Hits	342	Shared Neighborhood Hits	170
SwissProt Accessions	P20357	Gene names	Map2, Mtap2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2).

BICD1_MOUSE
NC score	0.048442 (rank : 1729)	θ value	3.0926 (rank : 2132)
Query Neighborhood Hits	2923	Target Neighborhood Hits	837	Shared Neighborhood Hits	341
SwissProt Accessions	Q8BR07, O55206, Q8BQ18, Q8BRR8, Q8C4D3, Q8CAK6, Q8R2J4, Q8R2J5, Q8R2J6, Q91YP7	Gene names	Bicd1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

ADDB_MOUSE
NC score	0.048126 (rank : 1730)	θ value	3.77169e-06 (rank : 904)
Query Neighborhood Hits	2923	Target Neighborhood Hits	574	Shared Neighborhood Hits	248
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

HC127_HUMAN
NC score	0.048000 (rank : 1731)	θ value	0.0431538 (rank : 1285)
Query Neighborhood Hits	2923	Target Neighborhood Hits	292	Shared Neighborhood Hits	159
SwissProt Accessions	Q9NQZ6, Q5JTF9, Q9H9C3, Q9H9H7, Q9ULQ4	Gene names	HCA127, KIAA1166
Domain Architecture	No domain graphic available
Description	Hepatocellular carcinoma-associated antigen 127.

HC127_MOUSE
NC score	0.048000 (rank : 1732)	θ value	0.0431538 (rank : 1286)
Query Neighborhood Hits	2923	Target Neighborhood Hits	292	Shared Neighborhood Hits	159
SwissProt Accessions	Q68FG0, Q6ZPW6	Gene names	Hca127, Kiaa1166
Domain Architecture	No domain graphic available
Description	Hepatocellular carcinoma-associated antigen 127 homolog.

SCN4B_HUMAN
NC score	0.047864 (rank : 1733)	θ value	3.0926 (rank : 2220)
Query Neighborhood Hits	2923	Target Neighborhood Hits	68	Shared Neighborhood Hits	57
SwissProt Accessions	Q8IWT1, Q6PIG5	Gene names	SCN4B
Domain Architecture	No domain graphic available
Description	Sodium channel beta-4 subunit precursor.

SAFB2_HUMAN
NC score	0.047517 (rank : 1734)	θ value	0.00298849 (rank : 1131)
Query Neighborhood Hits	2923	Target Neighborhood Hits	720	Shared Neighborhood Hits	303
SwissProt Accessions	Q14151, Q8TB13	Gene names	SAFB2, KIAA0138
Domain Architecture
Description	Scaffold attachment factor B2.

TPM1_HUMAN
NC score	0.047392 (rank : 1735)	θ value	0.47712 (rank : 1642)
Query Neighborhood Hits	2923	Target Neighborhood Hits	716	Shared Neighborhood Hits	305
SwissProt Accessions	P09493, P09494, P10469, Q86W64, Q96IK2, Q9UCY9	Gene names	TPM1, TMSA
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

RENT2_HUMAN
NC score	0.047345 (rank : 1736)	θ value	2.36792 (rank : 2095)
Query Neighborhood Hits	2923	Target Neighborhood Hits	618	Shared Neighborhood Hits	288
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

TACC1_MOUSE
NC score	0.047261 (rank : 1737)	θ value	8.99809 (rank : 2894)
Query Neighborhood Hits	2923	Target Neighborhood Hits	667	Shared Neighborhood Hits	328
SwissProt Accessions	Q6Y685, Q6Y686	Gene names	Tacc1
Domain Architecture	No domain graphic available
Description	Transforming acidic coiled-coil-containing protein 1.

CTGE5_MOUSE
NC score	0.047197 (rank : 1738)	θ value	0.365318 (rank : 1546)
Query Neighborhood Hits	2923	Target Neighborhood Hits	928	Shared Neighborhood Hits	381
SwissProt Accessions	Q8R311, Q8CIE3	Gene names	Ctage5, Mea6, Mgea6
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 5 homolog (cTAGE-5 protein) (Meningioma-expressed antigen 6).

CF010_HUMAN
NC score	0.047159 (rank : 1739)	θ value	6.88961 (rank : 2564)
Query Neighborhood Hits	2923	Target Neighborhood Hits	329	Shared Neighborhood Hits	152
SwissProt Accessions	Q5SRN2, Q5SPI9, Q5SPJ0, Q5SPK9, Q5SPL0, Q5SRN3, Q5TG25, Q5TG26, Q8N4B6	Gene names	C6orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf10.

MYO10_HUMAN
NC score	0.047141 (rank : 1740)	θ value	0.62314 (rank : 1680)
Query Neighborhood Hits	2923	Target Neighborhood Hits	920	Shared Neighborhood Hits	387
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

CD7_HUMAN
NC score	0.047075 (rank : 1741)	θ value	1.38821 (rank : 1829)
Query Neighborhood Hits	2923	Target Neighborhood Hits	190	Shared Neighborhood Hits	90
SwissProt Accessions	P09564	Gene names	CD7
Domain Architecture
Description	T-cell antigen CD7 precursor (GP40) (T-cell leukemia antigen) (TP41) (Leu-9).

FYCO1_MOUSE
NC score	0.046673 (rank : 1742)	θ value	6.88961 (rank : 2603)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1059	Shared Neighborhood Hits	372
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

AMPH_HUMAN
NC score	0.046661 (rank : 1743)	θ value	0.0148317 (rank : 1210)
Query Neighborhood Hits	2923	Target Neighborhood Hits	455	Shared Neighborhood Hits	204
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

MAP9_HUMAN
NC score	0.046609 (rank : 1744)	θ value	5.27518 (rank : 2459)
Query Neighborhood Hits	2923	Target Neighborhood Hits	518	Shared Neighborhood Hits	261
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

MAP9_MOUSE
NC score	0.046569 (rank : 1745)	θ value	4.03905 (rank : 2315)
Query Neighborhood Hits	2923	Target Neighborhood Hits	529	Shared Neighborhood Hits	258
SwissProt Accessions	Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7	Gene names	Map9, Asap
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

PHLB1_MOUSE
NC score	0.046513 (rank : 1746)	θ value	0.813845 (rank : 1741)
Query Neighborhood Hits	2923	Target Neighborhood Hits	678	Shared Neighborhood Hits	302
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

TACC3_HUMAN
NC score	0.046432 (rank : 1747)	θ value	8.99809 (rank : 2895)
Query Neighborhood Hits	2923	Target Neighborhood Hits	779	Shared Neighborhood Hits	341
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

RL1D1_HUMAN
NC score	0.046241 (rank : 1748)	θ value	0.365318 (rank : 1566)
Query Neighborhood Hits	2923	Target Neighborhood Hits	180	Shared Neighborhood Hits	111
SwissProt Accessions	O76021, Q6PL22, Q8IWS7, Q8WUZ1, Q9HDA9, Q9Y3Z9	Gene names	RSL1D1, CATX11, CSIG, PBK1
Domain Architecture	No domain graphic available
Description	Ribosomal L1 domain-containing protein 1 (Cellular senescence- inhibited gene protein) (Protein PBK1) (CATX-11).

AFF1_HUMAN
NC score	0.046158 (rank : 1749)	θ value	6.88961 (rank : 2545)
Query Neighborhood Hits	2923	Target Neighborhood Hits	506	Shared Neighborhood Hits	226
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

VDP_HUMAN
NC score	0.046042 (rank : 1750)	θ value	0.813845 (rank : 1759)
Query Neighborhood Hits	2923	Target Neighborhood Hits	645	Shared Neighborhood Hits	282
SwissProt Accessions	O60763	Gene names	VDP
Domain Architecture
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

SYNE1_HUMAN
NC score	0.046034 (rank : 1751)	θ value	0.21417 (rank : 1478)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1484	Shared Neighborhood Hits	466
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

PTPRN_HUMAN
NC score	0.045955 (rank : 1752)	θ value	0.47712 (rank : 1625)
Query Neighborhood Hits	2923	Target Neighborhood Hits	156	Shared Neighborhood Hits	56
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

K1543_MOUSE
NC score	0.045759 (rank : 1753)	θ value	0.0330416 (rank : 1267)
Query Neighborhood Hits	2923	Target Neighborhood Hits	497	Shared Neighborhood Hits	204
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

CHCH3_MOUSE
NC score	0.045719 (rank : 1754)	θ value	0.279714 (rank : 1488)
Query Neighborhood Hits	2923	Target Neighborhood Hits	249	Shared Neighborhood Hits	153
SwissProt Accessions	Q9CRB9	Gene names	Chchd3
Domain Architecture	No domain graphic available
Description	Coiled-coil-helix-coiled-coil-helix domain-containing protein 3.

PRP5_HUMAN
NC score	0.045649 (rank : 1755)	θ value	1.81305 (rank : 1971)
Query Neighborhood Hits	2923	Target Neighborhood Hits	108	Shared Neighborhood Hits	48
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

CBP_HUMAN
NC score	0.045610 (rank : 1756)	θ value	3.0926 (rank : 2140)
Query Neighborhood Hits	2923	Target Neighborhood Hits	941	Shared Neighborhood Hits	366
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

MEGF9_MOUSE
NC score	0.045593 (rank : 1757)	θ value	1.81305 (rank : 1959)
Query Neighborhood Hits	2923	Target Neighborhood Hits	896	Shared Neighborhood Hits	263
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

NFM_MOUSE
NC score	0.045525 (rank : 1758)	θ value	0.00102713 (rank : 1085)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1159	Shared Neighborhood Hits	478
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

BPAEA_HUMAN
NC score	0.045461 (rank : 1759)	θ value	5.27518 (rank : 2390)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1369	Shared Neighborhood Hits	447
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

ESCO1_HUMAN
NC score	0.045426 (rank : 1760)	θ value	0.0113563 (rank : 1198)
Query Neighborhood Hits	2923	Target Neighborhood Hits	361	Shared Neighborhood Hits	190
SwissProt Accessions	Q5FWF5, Q69YG4, Q69YS3, Q6IMD7, Q8N3Z5, Q8NBG2, Q96PX7	Gene names	ESCO1, EFO1, KIAA1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1) (Establishment factor- like protein 1) (EFO1p) (hEFO1) (CTF7 homolog 1).

RTN4_MOUSE
NC score	0.045322 (rank : 1761)	θ value	0.00869519 (rank : 1188)
Query Neighborhood Hits	2923	Target Neighborhood Hits	341	Shared Neighborhood Hits	176
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

RADI_HUMAN
NC score	0.045222 (rank : 1762)	θ value	0.000461057 (rank : 1055)
Query Neighborhood Hits	2923	Target Neighborhood Hits	741	Shared Neighborhood Hits	316
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

STMN1_HUMAN
NC score	0.045108 (rank : 1763)	θ value	1.81305 (rank : 1988)
Query Neighborhood Hits	2923	Target Neighborhood Hits	554	Shared Neighborhood Hits	291
SwissProt Accessions	P16949	Gene names	STMN1, LAP18, OP18
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Protein Pr22).

CCNB3_HUMAN
NC score	0.045065 (rank : 1764)	θ value	7.1131e-05 (rank : 987)
Query Neighborhood Hits	2923	Target Neighborhood Hits	368	Shared Neighborhood Hits	196
SwissProt Accessions	Q8WWL7, Q96SB5, Q96SB6, Q96SB7, Q9NT38	Gene names	CCNB3, CYCB3
Domain Architecture
Description	G2/mitotic-specific cyclin-B3.

ANK2_HUMAN
NC score	0.045063 (rank : 1765)	θ value	0.00020696 (rank : 1025)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1615	Shared Neighborhood Hits	546
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

TRI42_HUMAN
NC score	0.045023 (rank : 1766)	θ value	0.0431538 (rank : 1297)
Query Neighborhood Hits	2923	Target Neighborhood Hits	283	Shared Neighborhood Hits	74
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

CTGE5_HUMAN
NC score	0.044964 (rank : 1767)	θ value	5.27518 (rank : 2404)
Query Neighborhood Hits	2923	Target Neighborhood Hits	800	Shared Neighborhood Hits	348
SwissProt Accessions	O15320, O00169, Q6P2R8, Q8IX92, Q8IX93	Gene names	CTAGE5, MEA11, MEA6, MGEA11, MGEA6
Domain Architecture
Description	Cutaneous T-cell lymphoma-associated antigen 5 (cTAGE-5 protein) (cTAGE family member 5) (Meningioma-expressed antigen 6/11).

CD79B_MOUSE
NC score	0.044819 (rank : 1768)	θ value	0.365318 (rank : 1539)
Query Neighborhood Hits	2923	Target Neighborhood Hits	150	Shared Neighborhood Hits	78
SwissProt Accessions	P15530	Gene names	Cd79b, Igb
Domain Architecture
Description	B-cell antigen receptor complex-associated protein beta-chain precursor (B-cell-specific glycoprotein B29) (Immunoglobulin- associated B29 protein) (IG-beta) (CD79b antigen).

MOG_HUMAN
NC score	0.044531 (rank : 1769)	θ value	0.163984 (rank : 1426)
Query Neighborhood Hits	2923	Target Neighborhood Hits	73	Shared Neighborhood Hits	63
SwissProt Accessions	Q16653, O00713, O00714, O00715, Q13054, Q13055, Q14855, Q92891, Q92892, Q92893, Q92894, Q92895, Q93053, Q96KU9, Q96KV0, Q96KV1, Q99605	Gene names	MOG
Domain Architecture
Description	Myelin-oligodendrocyte glycoprotein precursor.

LAMA5_HUMAN
NC score	0.044349 (rank : 1770)	θ value	2.36792 (rank : 2075)
Query Neighborhood Hits	2923	Target Neighborhood Hits	976	Shared Neighborhood Hits	298
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

K0319_MOUSE
NC score	0.044342 (rank : 1771)	θ value	0.00298849 (rank : 1126)
Query Neighborhood Hits	2923	Target Neighborhood Hits	134	Shared Neighborhood Hits	61
SwissProt Accessions	Q5SZV5, Q80U39	Gene names	Kiaa0319
Domain Architecture	No domain graphic available
Description	Protein KIAA0319 precursor.

CBP_MOUSE
NC score	0.044285 (rank : 1772)	θ value	0.813845 (rank : 1711)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1051	Shared Neighborhood Hits	407
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

RADI_MOUSE
NC score	0.044237 (rank : 1773)	θ value	0.00665767 (rank : 1172)
Query Neighborhood Hits	2923	Target Neighborhood Hits	773	Shared Neighborhood Hits	329
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

CABIN_HUMAN
NC score	0.044229 (rank : 1774)	θ value	0.0736092 (rank : 1328)
Query Neighborhood Hits	2923	Target Neighborhood Hits	490	Shared Neighborhood Hits	172
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

KIF4A_HUMAN
NC score	0.044221 (rank : 1775)	θ value	1.38821 (rank : 1859)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1159	Shared Neighborhood Hits	440
SwissProt Accessions	O95239, Q86TN3, Q86XX7, Q9NNY6, Q9NY24, Q9UMW3	Gene names	KIF4A, KIF4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

RTP3_MOUSE
NC score	0.044176 (rank : 1776)	θ value	0.279714 (rank : 1520)
Query Neighborhood Hits	2923	Target Neighborhood Hits	374	Shared Neighborhood Hits	174
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

MYO6_HUMAN
NC score	0.044110 (rank : 1777)	θ value	1.38821 (rank : 1866)
Query Neighborhood Hits	2923	Target Neighborhood Hits	727	Shared Neighborhood Hits	341
SwissProt Accessions	Q9UM54, Q9BZZ7, Q9UEG2	Gene names	MYO6, KIAA0389
Domain Architecture
Description	Myosin-6 (Myosin VI).

CSKI1_HUMAN
NC score	0.044042 (rank : 1778)	θ value	8.99809 (rank : 2759)
Query Neighborhood Hits	2923	Target Neighborhood Hits	997	Shared Neighborhood Hits	353
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CU013_HUMAN
NC score	0.043971 (rank : 1779)	θ value	1.38821 (rank : 1832)
Query Neighborhood Hits	2923	Target Neighborhood Hits	405	Shared Neighborhood Hits	207
SwissProt Accessions	O95447	Gene names	C21orf13
Domain Architecture
Description	Protein C21orf13.

TRML1_MOUSE
NC score	0.043942 (rank : 1780)	θ value	0.0193708 (rank : 1247)
Query Neighborhood Hits	2923	Target Neighborhood Hits	44	Shared Neighborhood Hits	29
SwissProt Accessions	Q8K558, Q9D3N6	Gene names	Treml1, Tlt1
Domain Architecture	No domain graphic available
Description	Trem-like transcript 1 protein precursor (TLT-1) (Triggering receptor expressed on myeloid cells-like protein 1).

SLIT2_HUMAN
NC score	0.043785 (rank : 1781)	θ value	0.279714 (rank : 1521)
Query Neighborhood Hits	2923	Target Neighborhood Hits	708	Shared Neighborhood Hits	125
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

IGHG3_HUMAN
NC score	0.043711 (rank : 1782)	θ value	0.00509761 (rank : 1150)
Query Neighborhood Hits	2923	Target Neighborhood Hits	234	Shared Neighborhood Hits	79
SwissProt Accessions	P01860	Gene names	IGHG3
Domain Architecture
Description	Ig gamma-3 chain C region (Heavy chain disease protein) (HDC).

KINH_HUMAN
NC score	0.043676 (rank : 1783)	θ value	6.88961 (rank : 2630)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1231	Shared Neighborhood Hits	456
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

AKAP2_MOUSE
NC score	0.043643 (rank : 1784)	θ value	0.0961366 (rank : 1357)
Query Neighborhood Hits	2923	Target Neighborhood Hits	385	Shared Neighborhood Hits	181
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

DMD_MOUSE
NC score	0.043472 (rank : 1785)	θ value	5.27518 (rank : 2409)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1111	Shared Neighborhood Hits	410
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

LIRA3_HUMAN
NC score	0.043400 (rank : 1786)	θ value	0.163984 (rank : 1425)
Query Neighborhood Hits	2923	Target Neighborhood Hits	92	Shared Neighborhood Hits	63
SwissProt Accessions	Q8N6C8, O15469, O15470, O75016, Q8N151, Q8N154, Q8NHJ1, Q8NHJ2, Q8NHJ3, Q8NHJ4	Gene names	LILRA3, ILT6, LIR4
Domain Architecture	No domain graphic available
Description	Leukocyte immunoglobulin-like receptor subfamily A member 3 precursor (Leukocyte immunoglobulin-like receptor 4) (LIR-4) (Immunoglobulin- like transcript 6) (ILT-6) (Monocyte inhibitory receptor HM43/HM31) (CD85e antigen).

CD244_MOUSE
NC score	0.043393 (rank : 1787)	θ value	0.0113563 (rank : 1196)
Query Neighborhood Hits	2923	Target Neighborhood Hits	38	Shared Neighborhood Hits	25
SwissProt Accessions	Q07763, O88654, Q9JIE0	Gene names	Cd244, 2b4, Nmrk
Domain Architecture
Description	Natural killer cell receptor 2B4 precursor (NKR2B4) (NK cell type I receptor protein 2B4) (CD244 antigen) (Non MHC restricted killing associated).

MLL4_HUMAN
NC score	0.043356 (rank : 1788)	θ value	6.88961 (rank : 2652)
Query Neighborhood Hits	2923	Target Neighborhood Hits	722	Shared Neighborhood Hits	298
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

ASPP1_HUMAN
NC score	0.043352 (rank : 1789)	θ value	8.99809 (rank : 2733)
Query Neighborhood Hits	2923	Target Neighborhood Hits	956	Shared Neighborhood Hits	362
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

HEMGN_HUMAN
NC score	0.043334 (rank : 1790)	θ value	4.1701e-05 (rank : 975)
Query Neighborhood Hits	2923	Target Neighborhood Hits	92	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BXL5, Q6XAR3, Q86XY5, Q9NPC0	Gene names	HEMGN, EDAG, NDR
Domain Architecture	No domain graphic available
Description	Hemogen (Hemopoietic gene protein) (Negative differentiation regulator protein) (Erythroid differentiation-associated gene protein) (EDAG-1).

CSKI1_MOUSE
NC score	0.043274 (rank : 1791)	θ value	0.21417 (rank : 1452)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1031	Shared Neighborhood Hits	364
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

ANGL3_MOUSE
NC score	0.043229 (rank : 1792)	θ value	0.163984 (rank : 1406)
Query Neighborhood Hits	2923	Target Neighborhood Hits	306	Shared Neighborhood Hits	157
SwissProt Accessions	Q9R182	Gene names	Angptl3
Domain Architecture
Description	Angiopoietin-related protein 3 precursor (Angiopoietin-like 3).

CDC37_HUMAN
NC score	0.043223 (rank : 1793)	θ value	6.88961 (rank : 2561)
Query Neighborhood Hits	2923	Target Neighborhood Hits	506	Shared Neighborhood Hits	254
SwissProt Accessions	Q16543	Gene names	CDC37
Domain Architecture
Description	Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37).

CRLF2_MOUSE
NC score	0.043205 (rank : 1794)	θ value	0.365318 (rank : 1544)
Query Neighborhood Hits	2923	Target Neighborhood Hits	39	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CII9, Q9CRJ6, Q9JIE7, Q9JIQ7, Q9JJH8, Q9JMD5	Gene names	Crlf2, Crlm2, Tpte2, Tslpr
Domain Architecture
Description	Cytokine receptor-like factor 2 precursor (Type I cytokine receptor delta 1) (Cytokine receptor-like molecule 2) (CRLM-2) (Thymic stromal lymphopoietin protein receptor) (TSLPR).

ZAN_MOUSE
NC score	0.043050 (rank : 1795)	θ value	0.163984 (rank : 1438)
Query Neighborhood Hits	2923	Target Neighborhood Hits	808	Shared Neighborhood Hits	198
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

GP73_HUMAN
NC score	0.043039 (rank : 1796)	θ value	0.813845 (rank : 1723)
Query Neighborhood Hits	2923	Target Neighborhood Hits	309	Shared Neighborhood Hits	178
SwissProt Accessions	Q8NBJ4, Q6IAF4, Q9NRB9	Gene names	GOLPH2
Domain Architecture	No domain graphic available
Description	Golgi phosphoprotein 2 (Golgi membrane protein GP73).

SLIT2_MOUSE
NC score	0.042960 (rank : 1797)	θ value	1.38821 (rank : 1887)
Query Neighborhood Hits	2923	Target Neighborhood Hits	684	Shared Neighborhood Hits	123
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

PLVAP_HUMAN
NC score	0.042744 (rank : 1798)	θ value	3.0926 (rank : 2209)
Query Neighborhood Hits	2923	Target Neighborhood Hits	397	Shared Neighborhood Hits	226
SwissProt Accessions	Q9BX97, Q86VP0, Q8N8Y0, Q8ND68, Q8TER8, Q9BZD5	Gene names	PLVAP, FELS, PV1
Domain Architecture	No domain graphic available
Description	Plasmalemma vesicle-associated protein (Plasmalemma vesicle protein 1) (PV-1) (Fenestrated endothelial-linked structure protein).

IGHG1_HUMAN
NC score	0.042711 (rank : 1799)	θ value	0.00134147 (rank : 1094)
Query Neighborhood Hits	2923	Target Neighborhood Hits	229	Shared Neighborhood Hits	71
SwissProt Accessions	P01857	Gene names	IGHG1
Domain Architecture
Description	Ig gamma-1 chain C region.

K0319_HUMAN
NC score	0.042640 (rank : 1800)	θ value	0.0736092 (rank : 1342)
Query Neighborhood Hits	2923	Target Neighborhood Hits	154	Shared Neighborhood Hits	64
SwissProt Accessions	Q5VV43, Q9UJC8, Q9Y4G7	Gene names	KIAA0319
Domain Architecture	No domain graphic available
Description	Protein KIAA0319 precursor.

APC_HUMAN
NC score	0.042604 (rank : 1801)	θ value	0.0330416 (rank : 1261)
Query Neighborhood Hits	2923	Target Neighborhood Hits	603	Shared Neighborhood Hits	275
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

GPS2_HUMAN
NC score	0.042595 (rank : 1802)	θ value	2.36792 (rank : 2051)
Query Neighborhood Hits	2923	Target Neighborhood Hits	459	Shared Neighborhood Hits	204
SwissProt Accessions	Q13227	Gene names	GPS2
Domain Architecture	No domain graphic available
Description	G protein pathway suppressor 2 (Protein GPS2).

TPM4_HUMAN
NC score	0.042563 (rank : 1803)	θ value	2.36792 (rank : 2112)
Query Neighborhood Hits	2923	Target Neighborhood Hits	525	Shared Neighborhood Hits	240
SwissProt Accessions	P67936, P07226, Q15659, Q9BU85, Q9H8Q3	Gene names	TPM4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4) (TM30p1).

CUTL2_HUMAN
NC score	0.042501 (rank : 1804)	θ value	0.0563607 (rank : 1307)
Query Neighborhood Hits	2923	Target Neighborhood Hits	906	Shared Neighborhood Hits	328
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

RPGR1_MOUSE
NC score	0.042452 (rank : 1805)	θ value	5.27518 (rank : 2501)
Query Neighborhood Hits	2923	Target Neighborhood Hits	713	Shared Neighborhood Hits	337
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

TIMD1_MOUSE
NC score	0.042424 (rank : 1806)	θ value	1.81305 (rank : 1995)
Query Neighborhood Hits	2923	Target Neighborhood Hits	97	Shared Neighborhood Hits	69
SwissProt Accessions	Q5QNS5, Q7TPU2, Q8VIM1, Q8VIM2	Gene names	Havcr1, Tim1, Timd1
Domain Architecture	No domain graphic available
Description	Hepatitis A virus cellular receptor 1 homolog precursor (HAVcr-1) (T cell immunoglobulin and mucin domain-containing protein 1) (TIMD-1) (T cell membrane protein 1) (TIM-1).

STMN1_MOUSE
NC score	0.042319 (rank : 1807)	θ value	5.27518 (rank : 2521)
Query Neighborhood Hits	2923	Target Neighborhood Hits	560	Shared Neighborhood Hits	289
SwissProt Accessions	P54227	Gene names	Stmn1, Lag, Lap18, Pr22
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Pr22 protein) (Leukemia-associated gene protein).

MEGF9_HUMAN
NC score	0.042201 (rank : 1808)	θ value	8.99809 (rank : 2832)
Query Neighborhood Hits	2923	Target Neighborhood Hits	557	Shared Neighborhood Hits	175
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

LAMA5_MOUSE
NC score	0.042156 (rank : 1809)	θ value	6.88961 (rank : 2642)
Query Neighborhood Hits	2923	Target Neighborhood Hits	828	Shared Neighborhood Hits	253
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

MACF1_HUMAN
NC score	0.042154 (rank : 1810)	θ value	1.81305 (rank : 1957)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1341	Shared Neighborhood Hits	421
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

SYNE2_HUMAN
NC score	0.042118 (rank : 1811)	θ value	3.0926 (rank : 2225)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1323	Shared Neighborhood Hits	443
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

FYB_HUMAN
NC score	0.042060 (rank : 1812)	θ value	0.365318 (rank : 1549)
Query Neighborhood Hits	2923	Target Neighborhood Hits	379	Shared Neighborhood Hits	170
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

MUCB_HUMAN
NC score	0.042051 (rank : 1813)	θ value	0.0563607 (rank : 1321)
Query Neighborhood Hits	2923	Target Neighborhood Hits	233	Shared Neighborhood Hits	77
SwissProt Accessions	P04220	Gene names
Domain Architecture	No domain graphic available
Description	Ig mu heavy chain disease protein (BOT).

ZN318_HUMAN
NC score	0.041937 (rank : 1814)	θ value	0.62314 (rank : 1698)
Query Neighborhood Hits	2923	Target Neighborhood Hits	497	Shared Neighborhood Hits	258
SwissProt Accessions	Q5VUA4, O94796, Q4G0E4, Q8NEM6, Q9UNU8, Q9Y2W9	Gene names	ZNF318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Endocrine regulatory protein).

LIRA2_HUMAN
NC score	0.041924 (rank : 1815)	θ value	8.99809 (rank : 2822)
Query Neighborhood Hits	2923	Target Neighborhood Hits	100	Shared Neighborhood Hits	71
SwissProt Accessions	Q8N149, O75020	Gene names	LILRA2, ILT1, LIR7
Domain Architecture
Description	Leukocyte immunoglobulin-like receptor subfamily A member 2 precursor (Leukocyte immunoglobulin-like receptor 7) (LIR-7) (Immunoglobulin- like transcript 1) (ILT-1) (CD85h antigen).

GCP60_HUMAN
NC score	0.041917 (rank : 1816)	θ value	0.813845 (rank : 1721)
Query Neighborhood Hits	2923	Target Neighborhood Hits	419	Shared Neighborhood Hits	207
SwissProt Accessions	Q9H3P7, Q5VTJ0, Q6P9F1, Q8IZC5, Q8N4D6, Q9H6U3	Gene names	ACBD3, GCP60
Domain Architecture	No domain graphic available
Description	Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi phosphoprotein 1) (GOLPH1) (Golgi complex-associated protein 1) (GOCAP1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7).

IGHG4_HUMAN
NC score	0.041897 (rank : 1817)	θ value	0.000786445 (rank : 1073)
Query Neighborhood Hits	2923	Target Neighborhood Hits	223	Shared Neighborhood Hits	69
SwissProt Accessions	P01861	Gene names	IGHG4
Domain Architecture
Description	Ig gamma-4 chain C region.

MUC_HUMAN
NC score	0.041758 (rank : 1818)	θ value	0.0330416 (rank : 1270)
Query Neighborhood Hits	2923	Target Neighborhood Hits	231	Shared Neighborhood Hits	77
SwissProt Accessions	P01871	Gene names	IGHM
Domain Architecture
Description	Ig mu chain C region.

MYO6_MOUSE
NC score	0.041572 (rank : 1819)	θ value	4.03905 (rank : 2321)
Query Neighborhood Hits	2923	Target Neighborhood Hits	586	Shared Neighborhood Hits	286
SwissProt Accessions	Q64331	Gene names	Myo6, Sv
Domain Architecture
Description	Myosin-6 (Myosin VI).

DMD_HUMAN
NC score	0.041522 (rank : 1820)	θ value	1.81305 (rank : 1926)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1135	Shared Neighborhood Hits	413
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

LRSM1_HUMAN
NC score	0.041505 (rank : 1821)	θ value	0.813845 (rank : 1733)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1078	Shared Neighborhood Hits	379
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

ZRF1_MOUSE
NC score	0.041471 (rank : 1822)	θ value	0.62314 (rank : 1699)
Query Neighborhood Hits	2923	Target Neighborhood Hits	414	Shared Neighborhood Hits	195
SwissProt Accessions	P54103	Gene names	Zrf1, Dnajc2
Domain Architecture
Description	Zuotin-related factor 1.

MNT_HUMAN
NC score	0.041419 (rank : 1823)	θ value	2.36792 (rank : 2077)
Query Neighborhood Hits	2923	Target Neighborhood Hits	496	Shared Neighborhood Hits	219
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

PHF20_MOUSE
NC score	0.041370 (rank : 1824)	θ value	0.0431538 (rank : 1293)
Query Neighborhood Hits	2923	Target Neighborhood Hits	513	Shared Neighborhood Hits	219
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

MAVS_HUMAN
NC score	0.041335 (rank : 1825)	θ value	0.47712 (rank : 1613)
Query Neighborhood Hits	2923	Target Neighborhood Hits	271	Shared Neighborhood Hits	125
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

SAFB2_MOUSE
NC score	0.041257 (rank : 1826)	θ value	0.0330416 (rank : 1274)
Query Neighborhood Hits	2923	Target Neighborhood Hits	581	Shared Neighborhood Hits	253
SwissProt Accessions	Q80YR5, Q8K153	Gene names	Safb2
Domain Architecture
Description	Scaffold attachment factor B2.

LAMB1_MOUSE
NC score	0.041047 (rank : 1827)	θ value	8.99809 (rank : 2820)
Query Neighborhood Hits	2923	Target Neighborhood Hits	919	Shared Neighborhood Hits	303
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

MAGE1_HUMAN
NC score	0.040991 (rank : 1828)	θ value	0.62314 (rank : 1679)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1389	Shared Neighborhood Hits	441
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

FBX41_MOUSE
NC score	0.040949 (rank : 1829)	θ value	0.0736092 (rank : 1333)
Query Neighborhood Hits	2923	Target Neighborhood Hits	430	Shared Neighborhood Hits	201
SwissProt Accessions	Q6NS60, Q6P7W4, Q6ZPG1	Gene names	Fbxo41, D6Ertd538e, Kiaa1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

ALMS1_HUMAN
NC score	0.040908 (rank : 1830)	θ value	0.00390308 (rank : 1135)
Query Neighborhood Hits	2923	Target Neighborhood Hits	356	Shared Neighborhood Hits	149
SwissProt Accessions	Q8TCU4, Q53S05, Q580Q8, Q86VP9, Q9Y4G4	Gene names	ALMS1, KIAA0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1.

AL2S4_MOUSE
NC score	0.040869 (rank : 1831)	θ value	0.00175202 (rank : 1099)
Query Neighborhood Hits	2923	Target Neighborhood Hits	193	Shared Neighborhood Hits	79
SwissProt Accessions	Q3V0J1, Q3TIS2	Gene names	Als2cr4
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein homolog.

HPLN2_MOUSE
NC score	0.040791 (rank : 1832)	θ value	4.03905 (rank : 2289)
Query Neighborhood Hits	2923	Target Neighborhood Hits	102	Shared Neighborhood Hits	86
SwissProt Accessions	Q9ESM3	Gene names	Hapln2, Bral1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 2 precursor (Brain link protein 1).

LIPB1_MOUSE
NC score	0.040751 (rank : 1833)	θ value	0.62314 (rank : 1676)
Query Neighborhood Hits	2923	Target Neighborhood Hits	727	Shared Neighborhood Hits	312
SwissProt Accessions	Q8C8U0, Q69ZN5, Q6GQV3, Q80VB4, Q9CUT7	Gene names	Ppfibp1, Kiaa1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1).

FBX41_HUMAN
NC score	0.040737 (rank : 1834)	θ value	0.0736092 (rank : 1332)
Query Neighborhood Hits	2923	Target Neighborhood Hits	475	Shared Neighborhood Hits	214
SwissProt Accessions	Q8TF61	Gene names	FBXO41, FBX41, KIAA1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

CD4_MOUSE
NC score	0.040653 (rank : 1835)	θ value	2.36792 (rank : 2024)
Query Neighborhood Hits	2923	Target Neighborhood Hits	41	Shared Neighborhood Hits	30
SwissProt Accessions	P06332	Gene names	Cd4
Domain Architecture
Description	T-cell surface glycoprotein CD4 precursor (T-cell surface antigen T4/Leu-3) (T-cell differentiation antigen L3T4).

SIRPD_HUMAN
NC score	0.040596 (rank : 1836)	θ value	6.88961 (rank : 2692)
Query Neighborhood Hits	2923	Target Neighborhood Hits	117	Shared Neighborhood Hits	65
SwissProt Accessions	Q9H106, Q5TFQ6	Gene names	SIRPD, PTPNS1L2
Domain Architecture
Description	Signal-regulatory protein delta precursor (Protein tyrosine phosphatase non-receptor type substrate 1-like 2).

TRIM1_MOUSE
NC score	0.040467 (rank : 1837)	θ value	5.44631e-05 (rank : 986)
Query Neighborhood Hits	2923	Target Neighborhood Hits	361	Shared Neighborhood Hits	131
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

K1683_HUMAN
NC score	0.040418 (rank : 1838)	θ value	3.0926 (rank : 2178)
Query Neighborhood Hits	2923	Target Neighborhood Hits	240	Shared Neighborhood Hits	111
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

FA50A_MOUSE
NC score	0.040418 (rank : 1839)	θ value	0.279714 (rank : 1497)
Query Neighborhood Hits	2923	Target Neighborhood Hits	293	Shared Neighborhood Hits	169
SwissProt Accessions	Q9WV03, Q9D866	Gene names	Fam50a, D0HXS9928E, Xap5
Domain Architecture
Description	Protein FAM50A (XAP-5 protein).

EP15_HUMAN
NC score	0.040406 (rank : 1840)	θ value	0.47712 (rank : 1602)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1021	Shared Neighborhood Hits	376
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

BAZ2B_HUMAN
NC score	0.040350 (rank : 1841)	θ value	4.03905 (rank : 2257)
Query Neighborhood Hits	2923	Target Neighborhood Hits	803	Shared Neighborhood Hits	349
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

KINH_MOUSE
NC score	0.040236 (rank : 1842)	θ value	8.99809 (rank : 2812)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1082	Shared Neighborhood Hits	429
SwissProt Accessions	Q61768, O08711, Q61580	Gene names	Kif5b, Khcs, Kns1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

EZRI_MOUSE
NC score	0.040201 (rank : 1843)	θ value	5.27518 (rank : 2420)
Query Neighborhood Hits	2923	Target Neighborhood Hits	693	Shared Neighborhood Hits	313
SwissProt Accessions	P26040, Q80ZT8, Q9DCI1	Gene names	Vil2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

BPA1_MOUSE
NC score	0.040100 (rank : 1844)	θ value	6.88961 (rank : 2551)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1477	Shared Neighborhood Hits	473
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

OBF1_HUMAN
NC score	0.039911 (rank : 1845)	θ value	0.00134147 (rank : 1095)
Query Neighborhood Hits	2923	Target Neighborhood Hits	203	Shared Neighborhood Hits	81
SwissProt Accessions	Q16633, Q14983	Gene names	POU2AF1, OBF1
Domain Architecture	No domain graphic available
Description	POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (OCT-binding factor 1) (BOB-1) (OCA-B).

LZTS1_MOUSE
NC score	0.039790 (rank : 1846)	θ value	4.03905 (rank : 2313)
Query Neighborhood Hits	2923	Target Neighborhood Hits	540	Shared Neighborhood Hits	259
SwissProt Accessions	P60853	Gene names	Lzts1, Fez1
Domain Architecture	No domain graphic available
Description	Leucine zipper putative tumor suppressor 1 (F37/Esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

FLRT1_HUMAN
NC score	0.039788 (rank : 1847)	θ value	3.0926 (rank : 2169)
Query Neighborhood Hits	2923	Target Neighborhood Hits	286	Shared Neighborhood Hits	77
SwissProt Accessions	Q9NZU1	Gene names	FLRT1
Domain Architecture
Description	Leucine-rich repeat transmembrane protein FLRT1 precursor (Fibronectin-like domain-containing leucine-rich transmembrane protein 1).

K1802_MOUSE
NC score	0.039529 (rank : 1848)	θ value	3.29651e-10 (rank : 641)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1596	Shared Neighborhood Hits	405
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

AFF4_HUMAN
NC score	0.039355 (rank : 1849)	θ value	2.36792 (rank : 2010)
Query Neighborhood Hits	2923	Target Neighborhood Hits	611	Shared Neighborhood Hits	238
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

DNMT1_HUMAN
NC score	0.039222 (rank : 1850)	θ value	0.813845 (rank : 1718)
Query Neighborhood Hits	2923	Target Neighborhood Hits	401	Shared Neighborhood Hits	202
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

MNT_MOUSE
NC score	0.039152 (rank : 1851)	θ value	3.0926 (rank : 2191)
Query Neighborhood Hits	2923	Target Neighborhood Hits	432	Shared Neighborhood Hits	200
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MYO15_HUMAN
NC score	0.039138 (rank : 1852)	θ value	0.00869519 (rank : 1185)
Query Neighborhood Hits	2923	Target Neighborhood Hits	671	Shared Neighborhood Hits	254
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

CROP_HUMAN
NC score	0.039130 (rank : 1853)	θ value	4.03905 (rank : 2268)
Query Neighborhood Hits	2923	Target Neighborhood Hits	402	Shared Neighborhood Hits	207
SwissProt Accessions	O95232, Q6PHR9, Q9NUY0, Q9P2S7	Gene names	CROP, CREAP1, O48
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein (cAMP regulatory element-associated protein 1) (CRE-associated protein 1) (CREAP-1) (Luc7A) (Okadaic acid-inducible phosphoprotein OA48-18).

GCP60_MOUSE
NC score	0.039126 (rank : 1854)	θ value	1.06291 (rank : 1778)
Query Neighborhood Hits	2923	Target Neighborhood Hits	395	Shared Neighborhood Hits	189
SwissProt Accessions	Q8BMP6, O35371	Gene names	Acbd3, Gcp60, Pap7
Domain Architecture	No domain graphic available
Description	Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi phosphoprotein 1) (GOLPH1) (Golgi complex-associated protein 1) (GOCAP1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7).

TP53B_HUMAN
NC score	0.039017 (rank : 1855)	θ value	1.06291 (rank : 1815)
Query Neighborhood Hits	2923	Target Neighborhood Hits	413	Shared Neighborhood Hits	181
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

MACF1_MOUSE
NC score	0.038990 (rank : 1856)	θ value	1.38821 (rank : 1863)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1313	Shared Neighborhood Hits	419
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

CT116_HUMAN
NC score	0.038989 (rank : 1857)	θ value	5.27518 (rank : 2403)
Query Neighborhood Hits	2923	Target Neighborhood Hits	294	Shared Neighborhood Hits	174
SwissProt Accessions	Q96HY6, Q9BW47	Gene names	C20orf116
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf116 precursor.

CIC_HUMAN
NC score	0.038907 (rank : 1858)	θ value	0.62314 (rank : 1658)
Query Neighborhood Hits	2923	Target Neighborhood Hits	992	Shared Neighborhood Hits	344
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

LCP2_MOUSE
NC score	0.038887 (rank : 1859)	θ value	3.0926 (rank : 2185)
Query Neighborhood Hits	2923	Target Neighborhood Hits	177	Shared Neighborhood Hits	80
SwissProt Accessions	Q60787	Gene names	Lcp2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

KIF5C_MOUSE
NC score	0.038878 (rank : 1860)	θ value	1.81305 (rank : 1953)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1040	Shared Neighborhood Hits	398
SwissProt Accessions	P28738, Q9Z2F8	Gene names	Kif5c, Nkhc2
Domain Architecture
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

LIRA4_HUMAN
NC score	0.038830 (rank : 1861)	θ value	0.00869519 (rank : 1180)
Query Neighborhood Hits	2923	Target Neighborhood Hits	92	Shared Neighborhood Hits	64
SwissProt Accessions	P59901	Gene names	LILRA4, ILT7
Domain Architecture
Description	Leukocyte immunoglobulin-like receptor subfamily A member 4 precursor (Immunoglobulin-like transcript 7) (ILT-7) (CD85g antigen).

TRAIP_HUMAN
NC score	0.038825 (rank : 1862)	θ value	6.88961 (rank : 2703)
Query Neighborhood Hits	2923	Target Neighborhood Hits	780	Shared Neighborhood Hits	293
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

MERL_MOUSE
NC score	0.038585 (rank : 1863)	θ value	0.0563607 (rank : 1320)
Query Neighborhood Hits	2923	Target Neighborhood Hits	524	Shared Neighborhood Hits	256
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

CROP_MOUSE
NC score	0.038583 (rank : 1864)	θ value	4.03905 (rank : 2269)
Query Neighborhood Hits	2923	Target Neighborhood Hits	403	Shared Neighborhood Hits	209
SwissProt Accessions	Q5SUF2, Q3U9D5, Q8BUJ5, Q921Z3, Q9CRS7, Q9CTY4	Gene names	Crop
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein.

SYNJ1_MOUSE
NC score	0.038467 (rank : 1865)	θ value	8.99809 (rank : 2890)
Query Neighborhood Hits	2923	Target Neighborhood Hits	516	Shared Neighborhood Hits	240
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

IGHG1_MOUSE
NC score	0.038386 (rank : 1866)	θ value	0.00665767 (rank : 1168)
Query Neighborhood Hits	2923	Target Neighborhood Hits	219	Shared Neighborhood Hits	65
SwissProt Accessions	P01868	Gene names
Domain Architecture
Description	Ig gamma-1 chain C region secreted form.

MERL_HUMAN
NC score	0.038367 (rank : 1867)	θ value	0.0563607 (rank : 1319)
Query Neighborhood Hits	2923	Target Neighborhood Hits	532	Shared Neighborhood Hits	254
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

GP124_MOUSE
NC score	0.038362 (rank : 1868)	θ value	4.03905 (rank : 2285)
Query Neighborhood Hits	2923	Target Neighborhood Hits	423	Shared Neighborhood Hits	107
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

ANR12_HUMAN
NC score	0.038302 (rank : 1869)	θ value	1.81305 (rank : 1907)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1081	Shared Neighborhood Hits	410
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

IGH1M_MOUSE
NC score	0.038299 (rank : 1870)	θ value	0.00665767 (rank : 1167)
Query Neighborhood Hits	2923	Target Neighborhood Hits	223	Shared Neighborhood Hits	66
SwissProt Accessions	P01869	Gene names
Domain Architecture	No domain graphic available
Description	Ig gamma-1 chain C region, membrane-bound form.

TIMD4_MOUSE
NC score	0.038284 (rank : 1871)	θ value	0.00175202 (rank : 1109)
Query Neighborhood Hits	2923	Target Neighborhood Hits	65	Shared Neighborhood Hits	42
SwissProt Accessions	Q6U7R4, Q6U7R3, Q8CIC7	Gene names	Timd4, Tim4
Domain Architecture	No domain graphic available
Description	T-cell immunoglobulin and mucin domain-containing protein 4 precursor (TIMD-4) (T-cell membrane protein 4) (TIM-4) (Spleen, mucin- containing, knockout of lymphotoxin protein) (SMUCKLER).

RP1_MOUSE
NC score	0.038212 (rank : 1872)	θ value	0.0736092 (rank : 1351)
Query Neighborhood Hits	2923	Target Neighborhood Hits	104	Shared Neighborhood Hits	44
SwissProt Accessions	P56716	Gene names	Rp1, Orp1, Rp1h
Domain Architecture
Description	Oxygen-regulated protein 1 (Retinitis pigmentosa RP1 protein homolog).

MYO15_MOUSE
NC score	0.038165 (rank : 1873)	θ value	0.000602161 (rank : 1066)
Query Neighborhood Hits	2923	Target Neighborhood Hits	467	Shared Neighborhood Hits	183
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

RAI14_HUMAN
NC score	0.038126 (rank : 1874)	θ value	0.813845 (rank : 1744)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1367	Shared Neighborhood Hits	438
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

DIAP1_MOUSE
NC score	0.038100 (rank : 1875)	θ value	8.99809 (rank : 2765)
Query Neighborhood Hits	2923	Target Neighborhood Hits	839	Shared Neighborhood Hits	365
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

GP1BA_HUMAN
NC score	0.038001 (rank : 1876)	θ value	6.88961 (rank : 2613)
Query Neighborhood Hits	2923	Target Neighborhood Hits	407	Shared Neighborhood Hits	134
SwissProt Accessions	P07359, Q14441, Q16469, Q8N1F3, Q8NG39, Q9HDC7, Q9UEK1, Q9UQS4	Gene names	GP1BA
Domain Architecture
Description	Platelet glycoprotein Ib alpha chain precursor (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (Antigen CD42b-alpha) (CD42b antigen) [Contains: Glycocalicin].

BTNL8_HUMAN
NC score	0.037951 (rank : 1877)	θ value	6.88961 (rank : 2554)
Query Neighborhood Hits	2923	Target Neighborhood Hits	177	Shared Neighborhood Hits	102
SwissProt Accessions	Q6UX41, Q9H730	Gene names	BTNL8
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 8 precursor.

SCN4B_MOUSE
NC score	0.037947 (rank : 1878)	θ value	1.81305 (rank : 1980)
Query Neighborhood Hits	2923	Target Neighborhood Hits	59	Shared Neighborhood Hits	48
SwissProt Accessions	Q7M729	Gene names	Scn4b
Domain Architecture	No domain graphic available
Description	Sodium channel beta-4 subunit precursor.

GP124_HUMAN
NC score	0.037738 (rank : 1879)	θ value	6.88961 (rank : 2611)
Query Neighborhood Hits	2923	Target Neighborhood Hits	304	Shared Neighborhood Hits	72
SwissProt Accessions	Q96PE1, Q8N3R1, Q8TEM3, Q96KB2, Q9P1Z7, Q9UFY4	Gene names	GPR124, KIAA1531, TEM5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

AMPH_MOUSE
NC score	0.037654 (rank : 1880)	θ value	1.38821 (rank : 1820)
Query Neighborhood Hits	2923	Target Neighborhood Hits	291	Shared Neighborhood Hits	129
SwissProt Accessions	Q7TQF7, Q8R1C4	Gene names	Amph, Amph1
Domain Architecture
Description	Amphiphysin.

MYP0_HUMAN
NC score	0.037632 (rank : 1881)	θ value	2.36792 (rank : 2081)
Query Neighborhood Hits	2923	Target Neighborhood Hits	58	Shared Neighborhood Hits	46
SwissProt Accessions	P25189, Q16072, Q92677, Q9BR67	Gene names	MPZ
Domain Architecture
Description	Myelin P0 protein precursor (Myelin protein zero) (Myelin peripheral protein) (MPP).

SDPR_MOUSE
NC score	0.037494 (rank : 1882)	θ value	3.0926 (rank : 2221)
Query Neighborhood Hits	2923	Target Neighborhood Hits	485	Shared Neighborhood Hits	233
SwissProt Accessions	Q63918, Q3V1P6, Q78EC3, Q8CBT4	Gene names	Sdpr, Sdr
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein).

TRI18_HUMAN
NC score	0.037480 (rank : 1883)	θ value	7.1131e-05 (rank : 993)
Query Neighborhood Hits	2923	Target Neighborhood Hits	307	Shared Neighborhood Hits	93
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

ICAL_HUMAN
NC score	0.037316 (rank : 1884)	θ value	1.81305 (rank : 1941)
Query Neighborhood Hits	2923	Target Neighborhood Hits	275	Shared Neighborhood Hits	140
SwissProt Accessions	P20810, O95360, Q96D08, Q9H1Z5	Gene names	CAST
Domain Architecture
Description	Calpastatin (Calpain inhibitor) (Sperm BS-17 component).

PLCB1_HUMAN
NC score	0.037263 (rank : 1885)	θ value	0.279714 (rank : 1518)
Query Neighborhood Hits	2923	Target Neighborhood Hits	614	Shared Neighborhood Hits	287
SwissProt Accessions	Q9NQ66, O60325, Q5TFF7, Q5TGC9, Q8IV93, Q9BQW2, Q9H4H2, Q9H8H5, Q9NQ65, Q9NQH9, Q9NTH4, Q9UJP6, Q9UM26	Gene names	PLCB1, KIAA0581
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

CHCH3_HUMAN
NC score	0.037236 (rank : 1886)	θ value	5.27518 (rank : 2398)
Query Neighborhood Hits	2923	Target Neighborhood Hits	222	Shared Neighborhood Hits	133
SwissProt Accessions	Q9NX63	Gene names	CHCHD3
Domain Architecture	No domain graphic available
Description	Coiled-coil-helix-coiled-coil-helix domain-containing protein 3.

FMNL_HUMAN
NC score	0.037163 (rank : 1887)	θ value	5.27518 (rank : 2421)
Query Neighborhood Hits	2923	Target Neighborhood Hits	529	Shared Neighborhood Hits	285
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

K1802_HUMAN
NC score	0.037059 (rank : 1888)	θ value	1.87187e-05 (rank : 946)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1378	Shared Neighborhood Hits	365
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

FA50A_HUMAN
NC score	0.037018 (rank : 1889)	θ value	0.279714 (rank : 1496)
Query Neighborhood Hits	2923	Target Neighborhood Hits	264	Shared Neighborhood Hits	160
SwissProt Accessions	Q14320, Q5HY37	Gene names	FAM50A, DXS9928E, HXC26, XAP5
Domain Architecture
Description	Protein FAM50A (Protein XAP-5) (Protein HXC-26).

RP1L1_MOUSE
NC score	0.036960 (rank : 1890)	θ value	2.36792 (rank : 2099)
Query Neighborhood Hits	2923	Target Neighborhood Hits	170	Shared Neighborhood Hits	61
SwissProt Accessions	Q8CGM2, Q8K0I4	Gene names	Rp1l1, Rp1hl1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein (Retinitis pigmentosa 1-like protein 1).

EMSY_HUMAN
NC score	0.036934 (rank : 1891)	θ value	2.36792 (rank : 2044)
Query Neighborhood Hits	2923	Target Neighborhood Hits	296	Shared Neighborhood Hits	132
SwissProt Accessions	Q7Z589, Q4G109, Q8NBU6, Q8TE50, Q9H8I9, Q9NRH0	Gene names	EMSY, C11orf30
Domain Architecture
Description	Protein EMSY.

MTSS1_HUMAN
NC score	0.036865 (rank : 1892)	θ value	0.365318 (rank : 1560)
Query Neighborhood Hits	2923	Target Neighborhood Hits	504	Shared Neighborhood Hits	196
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

SETBP_HUMAN
NC score	0.036795 (rank : 1893)	θ value	0.125558 (rank : 1398)
Query Neighborhood Hits	2923	Target Neighborhood Hits	305	Shared Neighborhood Hits	145
SwissProt Accessions	Q9Y6X0, Q9UEF3	Gene names	SETBP1, KIAA0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

KIF5C_HUMAN
NC score	0.036695 (rank : 1894)	θ value	1.81305 (rank : 1952)
Query Neighborhood Hits	2923	Target Neighborhood Hits	974	Shared Neighborhood Hits	367
SwissProt Accessions	O60282, O95079	Gene names	KIF5C, KIAA0531, NKHC2
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

CENPH_HUMAN
NC score	0.036673 (rank : 1895)	θ value	6.88961 (rank : 2563)
Query Neighborhood Hits	2923	Target Neighborhood Hits	335	Shared Neighborhood Hits	188
SwissProt Accessions	Q9H3R5	Gene names	CENPH, ICEN35
Domain Architecture	No domain graphic available
Description	Centromere protein H (CENP-H) (Interphase centromere complex protein 35).

CN045_HUMAN
NC score	0.036662 (rank : 1896)	θ value	0.47712 (rank : 1598)
Query Neighborhood Hits	2923	Target Neighborhood Hits	227	Shared Neighborhood Hits	113
SwissProt Accessions	Q8ND07, Q9H5P8	Gene names	C14orf45
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf45.

SNPC4_HUMAN
NC score	0.036652 (rank : 1897)	θ value	0.365318 (rank : 1571)
Query Neighborhood Hits	2923	Target Neighborhood Hits	589	Shared Neighborhood Hits	233
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

STXB4_MOUSE
NC score	0.036630 (rank : 1898)	θ value	0.21417 (rank : 1477)
Query Neighborhood Hits	2923	Target Neighborhood Hits	629	Shared Neighborhood Hits	275
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

IL12B_HUMAN
NC score	0.036555 (rank : 1899)	θ value	3.0926 (rank : 2175)
Query Neighborhood Hits	2923	Target Neighborhood Hits	51	Shared Neighborhood Hits	40
SwissProt Accessions	P29460	Gene names	IL12B, NKSF2
Domain Architecture
Description	Interleukin-12 beta chain precursor (IL-12B) (IL-12 p40) (Cytotoxic lymphocyte maturation factor 40 kDa subunit) (CLMF p40) (NK cell stimulatory factor chain 2) (NKSF2).

HPLN4_HUMAN
NC score	0.036354 (rank : 1900)	θ value	0.47712 (rank : 1605)
Query Neighborhood Hits	2923	Target Neighborhood Hits	100	Shared Neighborhood Hits	84
SwissProt Accessions	Q86UW8, Q96PW2	Gene names	HAPLN4, BRAL2, KIAA1926
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 4 precursor (Brain link protein 2).

BTLA_HUMAN
NC score	0.036315 (rank : 1901)	θ value	0.279714 (rank : 1483)
Query Neighborhood Hits	2923	Target Neighborhood Hits	21	Shared Neighborhood Hits	15
SwissProt Accessions	Q7Z6A9, Q6ZNH9	Gene names	BTLA
Domain Architecture	No domain graphic available
Description	B- and T-lymphocyte attenuator precursor (B- and T-lymphocyte- associated protein) (CD272 antigen).

EMSY_MOUSE
NC score	0.036240 (rank : 1902)	θ value	0.21417 (rank : 1457)
Query Neighborhood Hits	2923	Target Neighborhood Hits	294	Shared Neighborhood Hits	132
SwissProt Accessions	Q8BMB0, Q5FWK5, Q80XU1, Q8VDW9	Gene names	Emsy
Domain Architecture
Description	Protein EMSY.

ANR11_HUMAN
NC score	0.036090 (rank : 1903)	θ value	0.21417 (rank : 1440)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1289	Shared Neighborhood Hits	451
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

SEPT9_HUMAN
NC score	0.035938 (rank : 1904)	θ value	3.19293e-05 (rank : 967)
Query Neighborhood Hits	2923	Target Neighborhood Hits	706	Shared Neighborhood Hits	261
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

DIDO1_HUMAN
NC score	0.035924 (rank : 1905)	θ value	0.279714 (rank : 1492)
Query Neighborhood Hits	2923	Target Neighborhood Hits	960	Shared Neighborhood Hits	328
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

U2AFM_HUMAN
NC score	0.035890 (rank : 1906)	θ value	3.0926 (rank : 2232)
Query Neighborhood Hits	2923	Target Neighborhood Hits	577	Shared Neighborhood Hits	273
SwissProt Accessions	Q15696	Gene names	ZRSR2, U2AF1-RS2, U2AF1L2, U2AF1RS2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2) (NY-REN-20 antigen).

PTN21_MOUSE
NC score	0.035852 (rank : 1907)	θ value	4.03905 (rank : 2337)
Query Neighborhood Hits	2923	Target Neighborhood Hits	155	Shared Neighborhood Hits	54
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

IGHG2_HUMAN
NC score	0.035842 (rank : 1908)	θ value	0.00509761 (rank : 1149)
Query Neighborhood Hits	2923	Target Neighborhood Hits	208	Shared Neighborhood Hits	60
SwissProt Accessions	P01859	Gene names	IGHG2
Domain Architecture
Description	Ig gamma-2 chain C region.

GPVI_MOUSE
NC score	0.035841 (rank : 1909)	θ value	6.88961 (rank : 2615)
Query Neighborhood Hits	2923	Target Neighborhood Hits	90	Shared Neighborhood Hits	66
SwissProt Accessions	P0C191	Gene names	Gp6
Domain Architecture	No domain graphic available
Description	Platelet glycoprotein VI precursor (GPVI).

ECM1_MOUSE
NC score	0.035805 (rank : 1910)	θ value	0.00020696 (rank : 1029)
Query Neighborhood Hits	2923	Target Neighborhood Hits	105	Shared Neighborhood Hits	44
SwissProt Accessions	Q61508	Gene names	Ecm1
Domain Architecture
Description	Extracellular matrix protein 1 precursor (Secretory component p85).

SLAF7_MOUSE
NC score	0.035790 (rank : 1911)	θ value	0.47712 (rank : 1631)
Query Neighborhood Hits	2923	Target Neighborhood Hits	46	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BHK6, Q8BTL2, Q8CJ63, Q8CJ64, Q8CJ65, Q91XA0	Gene names	Slamf7
Domain Architecture	No domain graphic available
Description	SLAM family member 7 precursor (Leukocyte cell-surface antigen) (Novel Ly9).

SKIL_HUMAN
NC score	0.035730 (rank : 1912)	θ value	1.06291 (rank : 1813)
Query Neighborhood Hits	2923	Target Neighborhood Hits	460	Shared Neighborhood Hits	223
SwissProt Accessions	P12757, O00464, P12756, Q07501	Gene names	SKIL, SNO
Domain Architecture
Description	Ski-like protein (Ski-related protein) (Ski-related oncogene).

PHF20_HUMAN
NC score	0.035673 (rank : 1913)	θ value	0.0330416 (rank : 1272)
Query Neighborhood Hits	2923	Target Neighborhood Hits	394	Shared Neighborhood Hits	176
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

ANGL3_HUMAN
NC score	0.035636 (rank : 1914)	θ value	2.36792 (rank : 2013)
Query Neighborhood Hits	2923	Target Neighborhood Hits	289	Shared Neighborhood Hits	141
SwissProt Accessions	Q9Y5C1	Gene names	ANGPTL3, ANGPT5
Domain Architecture
Description	Angiopoietin-related protein 3 precursor (Angiopoietin-like 3) (Angiopoietin-5) (ANG-5).

SPR1A_HUMAN
NC score	0.035578 (rank : 1915)	θ value	0.62314 (rank : 1694)
Query Neighborhood Hits	2923	Target Neighborhood Hits	136	Shared Neighborhood Hits	45
SwissProt Accessions	P35321, Q9UDG4	Gene names	SPRR1A
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein IA) (SPR-IA) (SPRK) (19 kDa pancornulin).

MYP0_MOUSE
NC score	0.035562 (rank : 1916)	θ value	2.36792 (rank : 2082)
Query Neighborhood Hits	2923	Target Neighborhood Hits	60	Shared Neighborhood Hits	46
SwissProt Accessions	P27573	Gene names	Mpz, P0
Domain Architecture
Description	Myelin P0 protein precursor (Myelin protein zero) (Myelin peripheral protein) (MPP).

GCBM_MOUSE
NC score	0.035557 (rank : 1917)	θ value	0.0148317 (rank : 1216)
Query Neighborhood Hits	2923	Target Neighborhood Hits	218	Shared Neighborhood Hits	65
SwissProt Accessions	P01867	Gene names
Domain Architecture
Description	Ig gamma-2B chain C region, membrane-bound form.

GCB_MOUSE
NC score	0.035542 (rank : 1918)	θ value	0.0148317 (rank : 1217)
Query Neighborhood Hits	2923	Target Neighborhood Hits	214	Shared Neighborhood Hits	63
SwissProt Accessions	P01866	Gene names
Domain Architecture	No domain graphic available
Description	Ig gamma-2B chain C region secreted form.

SYCP3_HUMAN
NC score	0.035460 (rank : 1919)	θ value	0.47712 (rank : 1636)
Query Neighborhood Hits	2923	Target Neighborhood Hits	276	Shared Neighborhood Hits	154
SwissProt Accessions	Q8IZU3	Gene names	SYCP3, SCP3
Domain Architecture	No domain graphic available
Description	Synaptonemal complex protein 3 (SCP-3).

WASF2_MOUSE
NC score	0.035456 (rank : 1920)	θ value	8.99809 (rank : 2914)
Query Neighborhood Hits	2923	Target Neighborhood Hits	315	Shared Neighborhood Hits	169
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

BAG3_MOUSE
NC score	0.035423 (rank : 1921)	θ value	0.47712 (rank : 1587)
Query Neighborhood Hits	2923	Target Neighborhood Hits	513	Shared Neighborhood Hits	229
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

TNNT3_MOUSE
NC score	0.035421 (rank : 1922)	θ value	2.36792 (rank : 2111)
Query Neighborhood Hits	2923	Target Neighborhood Hits	317	Shared Neighborhood Hits	188
SwissProt Accessions	Q9QZ47, O35575, O35576, O35577, O35578, O35579, O35580, O35581, O35582, O35583, O35584, O35585, P97456, Q99L89, Q9QZ46	Gene names	Tnnt3
Domain Architecture	No domain graphic available
Description	Troponin T, fast skeletal muscle (TnTf) (Fast skeletal muscle troponin T) (fTnT).

CCD12_MOUSE
NC score	0.035421 (rank : 1923)	θ value	0.0563607 (rank : 1305)
Query Neighborhood Hits	2923	Target Neighborhood Hits	50	Shared Neighborhood Hits	33
SwissProt Accessions	Q8R344, Q9CZH5	Gene names	Ccdc12
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 12.

TRI42_MOUSE
NC score	0.035389 (rank : 1924)	θ value	0.0736092 (rank : 1355)
Query Neighborhood Hits	2923	Target Neighborhood Hits	316	Shared Neighborhood Hits	69
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

LIPS_HUMAN
NC score	0.035382 (rank : 1925)	θ value	0.279714 (rank : 1511)
Query Neighborhood Hits	2923	Target Neighborhood Hits	314	Shared Neighborhood Hits	145
SwissProt Accessions	Q05469, Q3LRT2, Q6NSL7	Gene names	LIPE
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

AFAD_HUMAN
NC score	0.035314 (rank : 1926)	θ value	1.81305 (rank : 1904)
Query Neighborhood Hits	2923	Target Neighborhood Hits	689	Shared Neighborhood Hits	287
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

IASPP_MOUSE
NC score	0.035214 (rank : 1927)	θ value	8.99809 (rank : 2798)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1024	Shared Neighborhood Hits	291
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

IGHA2_HUMAN
NC score	0.035103 (rank : 1928)	θ value	0.813845 (rank : 1730)
Query Neighborhood Hits	2923	Target Neighborhood Hits	184	Shared Neighborhood Hits	62
SwissProt Accessions	P01877	Gene names	IGHA2
Domain Architecture
Description	Ig alpha-2 chain C region.

MLL3_HUMAN
NC score	0.035054 (rank : 1929)	θ value	6.88961 (rank : 2651)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1644	Shared Neighborhood Hits	509
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

SETBP_MOUSE
NC score	0.034990 (rank : 1930)	θ value	0.365318 (rank : 1569)
Query Neighborhood Hits	2923	Target Neighborhood Hits	352	Shared Neighborhood Hits	163
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

BCAR1_HUMAN
NC score	0.034920 (rank : 1931)	θ value	0.00228821 (rank : 1112)
Query Neighborhood Hits	2923	Target Neighborhood Hits	554	Shared Neighborhood Hits	188
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

SLAF6_MOUSE
NC score	0.034786 (rank : 1932)	θ value	4.03905 (rank : 2356)
Query Neighborhood Hits	2923	Target Neighborhood Hits	42	Shared Neighborhood Hits	37
SwissProt Accessions	Q9ET39, Q9ET40	Gene names	Slamf6, Ly108
Domain Architecture	No domain graphic available
Description	SLAM family member 6 precursor (Lymphocyte antigen 108).

CT116_MOUSE
NC score	0.034783 (rank : 1933)	θ value	2.36792 (rank : 2036)
Query Neighborhood Hits	2923	Target Neighborhood Hits	268	Shared Neighborhood Hits	151
SwissProt Accessions	Q80WW9, Q9CT52	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf116 homolog precursor.

U2AFM_MOUSE
NC score	0.034738 (rank : 1934)	θ value	8.99809 (rank : 2907)
Query Neighborhood Hits	2923	Target Neighborhood Hits	543	Shared Neighborhood Hits	257
SwissProt Accessions	Q62377	Gene names	Zrsr2, U2af1-rs2, U2af1l2, U2af1rs2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2).

MLL3_MOUSE
NC score	0.034719 (rank : 1935)	θ value	0.00869519 (rank : 1184)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1399	Shared Neighborhood Hits	455
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

PKHA6_MOUSE
NC score	0.034666 (rank : 1936)	θ value	0.163984 (rank : 1428)
Query Neighborhood Hits	2923	Target Neighborhood Hits	591	Shared Neighborhood Hits	250
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

CD79B_HUMAN
NC score	0.034659 (rank : 1937)	θ value	8.99809 (rank : 2746)
Query Neighborhood Hits	2923	Target Neighborhood Hits	143	Shared Neighborhood Hits	78
SwissProt Accessions	P40259, Q9BU06	Gene names	CD79B, B29, IGB
Domain Architecture
Description	B-cell antigen receptor complex-associated protein beta-chain precursor (B-cell-specific glycoprotein B29) (Immunoglobulin- associated B29 protein) (IG-beta) (CD79b antigen).

LIPB2_HUMAN
NC score	0.034583 (rank : 1938)	θ value	4.03905 (rank : 2308)
Query Neighborhood Hits	2923	Target Neighborhood Hits	599	Shared Neighborhood Hits	260
SwissProt Accessions	Q8ND30, O75337, Q8WW26	Gene names	PPFIBP2
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2).

AFF2_MOUSE
NC score	0.034557 (rank : 1939)	θ value	0.0736092 (rank : 1324)
Query Neighborhood Hits	2923	Target Neighborhood Hits	225	Shared Neighborhood Hits	107
SwissProt Accessions	O55112	Gene names	Aff2, Fmr2, Ox19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation protein 2 homolog) (Protein FMR-2) (FMR2P) (Protein Ox19).

IZUM1_HUMAN
NC score	0.034521 (rank : 1940)	θ value	0.279714 (rank : 1509)
Query Neighborhood Hits	2923	Target Neighborhood Hits	21	Shared Neighborhood Hits	17
SwissProt Accessions	Q8IYV9, Q6Q8P6, Q6Q8P7	Gene names	IZUMO1
Domain Architecture	No domain graphic available
Description	Izumo sperm-egg fusion protein 1 precursor (Sperm-specific protein izumo).

LIPB2_MOUSE
NC score	0.034507 (rank : 1941)	θ value	5.27518 (rank : 2453)
Query Neighborhood Hits	2923	Target Neighborhood Hits	570	Shared Neighborhood Hits	253
SwissProt Accessions	O35711, Q7TMG4, Q8CBS6, Q99KX6	Gene names	Ppfibp2, Cclp1
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2) (Coiled-coil-like protein 1).

PKD1_HUMAN
NC score	0.034468 (rank : 1942)	θ value	2.36792 (rank : 2091)
Query Neighborhood Hits	2923	Target Neighborhood Hits	387	Shared Neighborhood Hits	85
SwissProt Accessions	P98161, Q15140, Q15141	Gene names	PKD1
Domain Architecture
Description	Polycystin-1 precursor (Autosomal dominant polycystic kidney disease protein 1).

CASC3_MOUSE
NC score	0.034406 (rank : 1943)	θ value	0.365318 (rank : 1536)
Query Neighborhood Hits	2923	Target Neighborhood Hits	333	Shared Neighborhood Hits	143
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

PTN14_MOUSE
NC score	0.034327 (rank : 1944)	θ value	6.88961 (rank : 2680)
Query Neighborhood Hits	2923	Target Neighborhood Hits	142	Shared Neighborhood Hits	43
SwissProt Accessions	Q62130	Gene names	Ptpn14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36).

GC3M_MOUSE
NC score	0.034259 (rank : 1945)	θ value	0.279714 (rank : 1498)
Query Neighborhood Hits	2923	Target Neighborhood Hits	215	Shared Neighborhood Hits	60
SwissProt Accessions	P03987	Gene names
Domain Architecture
Description	Ig gamma-3 chain C region, membrane-bound form.

CD2_HUMAN
NC score	0.034252 (rank : 1946)	θ value	3.0926 (rank : 2144)
Query Neighborhood Hits	2923	Target Neighborhood Hits	504	Shared Neighborhood Hits	181
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

CCD12_HUMAN
NC score	0.034054 (rank : 1947)	θ value	0.0148317 (rank : 1213)
Query Neighborhood Hits	2923	Target Neighborhood Hits	39	Shared Neighborhood Hits	19
SwissProt Accessions	Q8WUD4, Q8N8I4	Gene names	CCDC12
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 12.

PRP40_MOUSE
NC score	0.034008 (rank : 1948)	θ value	0.365318 (rank : 1563)
Query Neighborhood Hits	2923	Target Neighborhood Hits	447	Shared Neighborhood Hits	208
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

GCAM_MOUSE
NC score	0.033946 (rank : 1949)	θ value	0.279714 (rank : 1501)
Query Neighborhood Hits	2923	Target Neighborhood Hits	214	Shared Neighborhood Hits	59
SwissProt Accessions	P01865	Gene names	Igh-1a
Domain Architecture
Description	Ig gamma-2A chain C region, membrane-bound form.

GCAB_MOUSE
NC score	0.033886 (rank : 1950)	θ value	0.0193708 (rank : 1233)
Query Neighborhood Hits	2923	Target Neighborhood Hits	203	Shared Neighborhood Hits	57
SwissProt Accessions	P01864	Gene names
Domain Architecture	No domain graphic available
Description	Ig gamma-2A chain C region secreted form (B allele).

GC3_MOUSE
NC score	0.033875 (rank : 1951)	θ value	0.279714 (rank : 1499)
Query Neighborhood Hits	2923	Target Neighborhood Hits	212	Shared Neighborhood Hits	58
SwissProt Accessions	P22436	Gene names
Domain Architecture	No domain graphic available
Description	Ig gamma-3 chain C region, secreted form.

TPX2_HUMAN
NC score	0.033807 (rank : 1952)	θ value	0.365318 (rank : 1574)
Query Neighborhood Hits	2923	Target Neighborhood Hits	150	Shared Neighborhood Hits	92
SwissProt Accessions	Q9ULW0, Q9H1R4, Q9NRA3, Q9UFN9, Q9UL00, Q9Y2M1	Gene names	TPX2, C20orf1, C20orf2, DIL2, HCA519
Domain Architecture	No domain graphic available
Description	Targeting protein for Xklp2 (Restricted expression proliferation- associated protein 100) (p100) (Differentially expressed in cancerous and noncancerous lung cells 2) (DIL-2) (Protein FLS353) (Hepatocellular carcinoma-associated antigen 519).

GCAA_MOUSE
NC score	0.033785 (rank : 1953)	θ value	0.279714 (rank : 1500)
Query Neighborhood Hits	2923	Target Neighborhood Hits	210	Shared Neighborhood Hits	57
SwissProt Accessions	P01863	Gene names
Domain Architecture
Description	Ig gamma-2A chain C region, A allele.

HASP_HUMAN
NC score	0.033776 (rank : 1954)	θ value	6.88961 (rank : 2618)
Query Neighborhood Hits	2923	Target Neighborhood Hits	64	Shared Neighborhood Hits	40
SwissProt Accessions	Q8TF76, Q5U5K3, Q96MN1, Q9BXS7	Gene names	GSG2
Domain Architecture
Description	Serine/threonine-protein kinase Haspin (EC 2.7.11.1) (Haploid germ cell-specific nuclear protein kinase) (H-Haspin) (Germ cell-specific gene 2 protein).

KIF23_HUMAN
NC score	0.033765 (rank : 1955)	θ value	8.99809 (rank : 2811)
Query Neighborhood Hits	2923	Target Neighborhood Hits	618	Shared Neighborhood Hits	316
SwissProt Accessions	Q02241	Gene names	KIF23, KNSL5, MKLP1
Domain Architecture
Description	Kinesin-like protein KIF23 (Mitotic kinesin-like protein 1) (Kinesin- like protein 5).

IF4G1_HUMAN
NC score	0.033686 (rank : 1956)	θ value	1.06291 (rank : 1787)
Query Neighborhood Hits	2923	Target Neighborhood Hits	347	Shared Neighborhood Hits	168
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

PODXL_MOUSE
NC score	0.033670 (rank : 1957)	θ value	0.62314 (rank : 1684)
Query Neighborhood Hits	2923	Target Neighborhood Hits	130	Shared Neighborhood Hits	69
SwissProt Accessions	Q9R0M4, Q9ESZ1	Gene names	Podxl, Pclp1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

SPR1B_HUMAN
NC score	0.033579 (rank : 1958)	θ value	1.38821 (rank : 1889)
Query Neighborhood Hits	2923	Target Neighborhood Hits	102	Shared Neighborhood Hits	38
SwissProt Accessions	P22528, P22529, P22530, Q5T524	Gene names	SPRR1B
Domain Architecture	No domain graphic available
Description	Cornifin B (Small proline-rich protein IB) (SPR-IB) (14.9 kDa pancornulin).

ICAM2_HUMAN
NC score	0.033501 (rank : 1959)	θ value	5.27518 (rank : 2441)
Query Neighborhood Hits	2923	Target Neighborhood Hits	21	Shared Neighborhood Hits	13
SwissProt Accessions	P13598, Q14600	Gene names	ICAM2
Domain Architecture
Description	Intercellular adhesion molecule 2 precursor (ICAM-2) (CD102 antigen).

TRI36_MOUSE
NC score	0.033471 (rank : 1960)	θ value	0.0193708 (rank : 1243)
Query Neighborhood Hits	2923	Target Neighborhood Hits	266	Shared Neighborhood Hits	86
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

SFRS8_HUMAN
NC score	0.033440 (rank : 1961)	θ value	1.81305 (rank : 1984)
Query Neighborhood Hits	2923	Target Neighborhood Hits	166	Shared Neighborhood Hits	81
SwissProt Accessions	Q12872	Gene names	SFRS8, SWAP
Domain Architecture
Description	Splicing factor, arginine/serine-rich 8 (Suppressor of white apricot protein homolog).

AF9_HUMAN
NC score	0.033287 (rank : 1962)	θ value	1.81305 (rank : 1903)
Query Neighborhood Hits	2923	Target Neighborhood Hits	202	Shared Neighborhood Hits	88
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

NUP88_HUMAN
NC score	0.033215 (rank : 1963)	θ value	6.88961 (rank : 2662)
Query Neighborhood Hits	2923	Target Neighborhood Hits	354	Shared Neighborhood Hits	198
SwissProt Accessions	Q99567, Q9BWE5	Gene names	NUP88
Domain Architecture	No domain graphic available
Description	Nuclear pore complex protein Nup88 (Nucleoporin Nup88) (88 kDa nuclear pore complex protein).

AFF2_HUMAN
NC score	0.033181 (rank : 1964)	θ value	0.00869519 (rank : 1175)
Query Neighborhood Hits	2923	Target Neighborhood Hits	218	Shared Neighborhood Hits	107
SwissProt Accessions	P51816, O43786, O60215, P78407, Q13521, Q14323, Q9UNA5	Gene names	AFF2, FMR2, OX19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation 2 protein) (Protein FMR-2) (FMR2P) (Protein Ox19) (Fragile X E mental retardation syndrome protein).

SF3A1_HUMAN
NC score	0.033167 (rank : 1965)	θ value	1.38821 (rank : 1884)
Query Neighborhood Hits	2923	Target Neighborhood Hits	199	Shared Neighborhood Hits	104
SwissProt Accessions	Q15459	Gene names	SF3A1, SAP114
Domain Architecture
Description	Splicing factor 3 subunit 1 (Spliceosome-associated protein 114) (SAP 114) (SF3a120).

PTN13_MOUSE
NC score	0.033107 (rank : 1966)	θ value	5.27518 (rank : 2495)
Query Neighborhood Hits	2923	Target Neighborhood Hits	426	Shared Neighborhood Hits	133
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

PRP40_HUMAN
NC score	0.033056 (rank : 1967)	θ value	0.62314 (rank : 1686)
Query Neighborhood Hits	2923	Target Neighborhood Hits	442	Shared Neighborhood Hits	202
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

ZRF1_HUMAN
NC score	0.032992 (rank : 1968)	θ value	4.03905 (rank : 2370)
Query Neighborhood Hits	2923	Target Neighborhood Hits	457	Shared Neighborhood Hits	216
SwissProt Accessions	Q99543	Gene names	ZRF1, DNAJC2, MPHOSPH11, MPP11
Domain Architecture
Description	Zuotin-related factor 1 (M-phase phosphoprotein 11).

ATX2L_MOUSE
NC score	0.032981 (rank : 1969)	θ value	0.125558 (rank : 1384)
Query Neighborhood Hits	2923	Target Neighborhood Hits	401	Shared Neighborhood Hits	158
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

NUP62_HUMAN
NC score	0.032930 (rank : 1970)	θ value	1.38821 (rank : 1869)
Query Neighborhood Hits	2923	Target Neighborhood Hits	195	Shared Neighborhood Hits	116
SwissProt Accessions	P37198, Q503A4, Q96C43, Q9NSL1	Gene names	NUP62
Domain Architecture
Description	Nuclear pore glycoprotein p62 (62 kDa nucleoporin).

ICAM2_MOUSE
NC score	0.032873 (rank : 1971)	θ value	1.81305 (rank : 1942)
Query Neighborhood Hits	2923	Target Neighborhood Hits	17	Shared Neighborhood Hits	11
SwissProt Accessions	P35330, Q9D8Q4	Gene names	Icam2, Icam-2
Domain Architecture
Description	Intercellular adhesion molecule 2 precursor (ICAM-2) (CD102 antigen) (Lymphocyte function-associated AG-1 counter-receptor).

MTSS1_MOUSE
NC score	0.032869 (rank : 1972)	θ value	0.47712 (rank : 1617)
Query Neighborhood Hits	2923	Target Neighborhood Hits	592	Shared Neighborhood Hits	215
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

SF01_HUMAN
NC score	0.032826 (rank : 1973)	θ value	6.88961 (rank : 2690)
Query Neighborhood Hits	2923	Target Neighborhood Hits	287	Shared Neighborhood Hits	134
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

ERMAP_MOUSE
NC score	0.032802 (rank : 1974)	θ value	2.36792 (rank : 2045)
Query Neighborhood Hits	2923	Target Neighborhood Hits	231	Shared Neighborhood Hits	118
SwissProt Accessions	Q9JLN5, Q3UV82, Q6P4T5, Q8CEH1	Gene names	Ermap
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor.

PGCA_HUMAN
NC score	0.032744 (rank : 1975)	θ value	0.62314 (rank : 1683)
Query Neighborhood Hits	2923	Target Neighborhood Hits	821	Shared Neighborhood Hits	258
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

BAZ1A_HUMAN
NC score	0.032733 (rank : 1976)	θ value	5.27518 (rank : 2387)
Query Neighborhood Hits	2923	Target Neighborhood Hits	693	Shared Neighborhood Hits	335
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

CD248_HUMAN
NC score	0.032730 (rank : 1977)	θ value	0.000602161 (rank : 1062)
Query Neighborhood Hits	2923	Target Neighborhood Hits	679	Shared Neighborhood Hits	193
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

HPLN4_MOUSE
NC score	0.032640 (rank : 1978)	θ value	1.06291 (rank : 1783)
Query Neighborhood Hits	2923	Target Neighborhood Hits	98	Shared Neighborhood Hits	78
SwissProt Accessions	Q80WM4, Q80XX2	Gene names	Hapln4, Bral2, Lpr4
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 4 precursor (Brain link protein 2) (Link protein 4).

ZCPW1_MOUSE
NC score	0.032413 (rank : 1979)	θ value	1.06291 (rank : 1818)
Query Neighborhood Hits	2923	Target Neighborhood Hits	307	Shared Neighborhood Hits	155
SwissProt Accessions	Q6IR42	Gene names	Zcwpw1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1 homolog.

GP179_HUMAN
NC score	0.032169 (rank : 1980)	θ value	0.62314 (rank : 1669)
Query Neighborhood Hits	2923	Target Neighborhood Hits	372	Shared Neighborhood Hits	147
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

GHR_HUMAN
NC score	0.032133 (rank : 1981)	θ value	0.0431538 (rank : 1284)
Query Neighborhood Hits	2923	Target Neighborhood Hits	57	Shared Neighborhood Hits	35
SwissProt Accessions	P10912, Q9HCX2	Gene names	GHR
Domain Architecture
Description	Growth hormone receptor precursor (GH receptor) (Somatotropin receptor) [Contains: Growth hormone-binding protein (GH-binding protein) (GHBP) (Serum-binding protein)].

LIRB5_HUMAN
NC score	0.032000 (rank : 1982)	θ value	0.125558 (rank : 1392)
Query Neighborhood Hits	2923	Target Neighborhood Hits	100	Shared Neighborhood Hits	62
SwissProt Accessions	O75023, Q8N760	Gene names	LILRB5, LIR8
Domain Architecture
Description	Leukocyte immunoglobulin-like receptor subfamily B member 5 precursor (Leukocyte immunoglobulin-like receptor 8) (LIR-8) (CD85c antigen).

KIF5A_HUMAN
NC score	0.031963 (rank : 1983)	θ value	1.81305 (rank : 1951)
Query Neighborhood Hits	2923	Target Neighborhood Hits	843	Shared Neighborhood Hits	341
SwissProt Accessions	Q12840, Q4LE26	Gene names	KIF5A, NKHC1
Domain Architecture
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

ANLN_MOUSE
NC score	0.031832 (rank : 1984)	θ value	1.81305 (rank : 1906)
Query Neighborhood Hits	2923	Target Neighborhood Hits	297	Shared Neighborhood Hits	167
SwissProt Accessions	Q8K298, Q8BL79, Q8BLB3, Q8K2N0, Q9CUY0	Gene names	Anln
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

BT2A3_HUMAN
NC score	0.031824 (rank : 1985)	θ value	0.813845 (rank : 1707)
Query Neighborhood Hits	2923	Target Neighborhood Hits	195	Shared Neighborhood Hits	94
SwissProt Accessions	Q96KV6	Gene names	BTN2A3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A3 precursor.

CS007_MOUSE
NC score	0.031797 (rank : 1986)	θ value	0.279714 (rank : 1491)
Query Neighborhood Hits	2923	Target Neighborhood Hits	464	Shared Neighborhood Hits	185
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

REN3A_HUMAN
NC score	0.031797 (rank : 1987)	θ value	1.06291 (rank : 1808)
Query Neighborhood Hits	2923	Target Neighborhood Hits	248	Shared Neighborhood Hits	128
SwissProt Accessions	Q9H1J1, Q5T8C3, Q5T8C9, Q7Z6N3, Q86YK1, Q9BZI8	Gene names	UPF3A, RENT3A, UPF3
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3A (Nonsense mRNA reducing factor 3A) (Up-frameshift suppressor 3 homolog A) (hUpf3).

KIF5A_MOUSE
NC score	0.031735 (rank : 1988)	θ value	2.36792 (rank : 2069)
Query Neighborhood Hits	2923	Target Neighborhood Hits	859	Shared Neighborhood Hits	341
SwissProt Accessions	P33175, Q5DTP1, Q6PDY7, Q9Z2F9	Gene names	Kif5a, Kiaa4086, Kif5, Nkhc1
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

MILK1_HUMAN
NC score	0.031654 (rank : 1989)	θ value	6.88961 (rank : 2650)
Query Neighborhood Hits	2923	Target Neighborhood Hits	427	Shared Neighborhood Hits	198
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

DZIP1_HUMAN
NC score	0.031648 (rank : 1990)	θ value	6.88961 (rank : 2591)
Query Neighborhood Hits	2923	Target Neighborhood Hits	675	Shared Neighborhood Hits	219
SwissProt Accessions	Q86YF9, Q8WY45, Q8WY46, Q9UGA5, Q9Y2K0	Gene names	DZIP1, DZIP, DZIP2, KIAA0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1/2).

HRX_HUMAN
NC score	0.031467 (rank : 1991)	θ value	4.03905 (rank : 2290)
Query Neighborhood Hits	2923	Target Neighborhood Hits	825	Shared Neighborhood Hits	328
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

AUTS2_HUMAN
NC score	0.031381 (rank : 1992)	θ value	8.99809 (rank : 2734)
Query Neighborhood Hits	2923	Target Neighborhood Hits	342	Shared Neighborhood Hits	168
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

SDS3_HUMAN
NC score	0.031257 (rank : 1993)	θ value	1.81305 (rank : 1981)
Query Neighborhood Hits	2923	Target Neighborhood Hits	257	Shared Neighborhood Hits	146
SwissProt Accessions	Q9H7L9, Q8N6H0, Q9H8D2	Gene names	SUDS3, SDS3
Domain Architecture	No domain graphic available
Description	Sin3 histone deacetylase corepressor complex component SDS3 (Suppressor of defective silencing 3 protein homolog).

NUCB2_MOUSE
NC score	0.031144 (rank : 1994)	θ value	5.27518 (rank : 2469)
Query Neighborhood Hits	2923	Target Neighborhood Hits	459	Shared Neighborhood Hits	224
SwissProt Accessions	P81117	Gene names	Nucb2, Nefa
Domain Architecture	No domain graphic available
Description	Nucleobindin-2 precursor (DNA-binding protein NEFA).

NUP62_MOUSE
NC score	0.031009 (rank : 1995)	θ value	1.81305 (rank : 1964)
Query Neighborhood Hits	2923	Target Neighborhood Hits	200	Shared Neighborhood Hits	109
SwissProt Accessions	Q63850, Q99JN7	Gene names	Nup62
Domain Architecture
Description	Nuclear pore glycoprotein p62 (62 kDa nucleoporin).

K1914_MOUSE
NC score	0.030781 (rank : 1996)	θ value	0.163984 (rank : 1424)
Query Neighborhood Hits	2923	Target Neighborhood Hits	216	Shared Neighborhood Hits	116
SwissProt Accessions	Q5DTU0, Q8BID1, Q8K2G0	Gene names	Kiaa1914
Domain Architecture	No domain graphic available
Description	Protein KIAA1914.

ECM1_HUMAN
NC score	0.030730 (rank : 1997)	θ value	0.21417 (rank : 1456)
Query Neighborhood Hits	2923	Target Neighborhood Hits	182	Shared Neighborhood Hits	84
SwissProt Accessions	Q16610	Gene names	ECM1
Domain Architecture
Description	Extracellular matrix protein 1 precursor (Secretory component p85).

ZN645_HUMAN
NC score	0.030719 (rank : 1998)	θ value	0.0330416 (rank : 1278)
Query Neighborhood Hits	2923	Target Neighborhood Hits	265	Shared Neighborhood Hits	78
SwissProt Accessions	Q8N7E2, Q6DJY9	Gene names	ZNF645
Domain Architecture	No domain graphic available
Description	Zinc finger protein 645.

I13R2_HUMAN
NC score	0.030465 (rank : 1999)	θ value	0.0736092 (rank : 1337)
Query Neighborhood Hits	2923	Target Neighborhood Hits	41	Shared Neighborhood Hits	24
SwissProt Accessions	Q14627, O00667	Gene names	IL13RA2, IL13R
Domain Architecture	No domain graphic available
Description	Interleukin-13 receptor alpha-2 chain precursor (Interleukin-13- binding protein) (CD213a2 antigen).

JADE2_MOUSE
NC score	0.030447 (rank : 2000)	θ value	5.44631e-05 (rank : 981)
Query Neighborhood Hits	2923	Target Neighborhood Hits	560	Shared Neighborhood Hits	207
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

BCAR1_MOUSE
NC score	0.029942 (rank : 2001)	θ value	0.47712 (rank : 1588)
Query Neighborhood Hits	2923	Target Neighborhood Hits	438	Shared Neighborhood Hits	155
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

TRI18_MOUSE
NC score	0.029937 (rank : 2002)	θ value	0.00390308 (rank : 1143)
Query Neighborhood Hits	2923	Target Neighborhood Hits	292	Shared Neighborhood Hits	78
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

SASH1_MOUSE
NC score	0.029928 (rank : 2003)	θ value	2.36792 (rank : 2101)
Query Neighborhood Hits	2923	Target Neighborhood Hits	263	Shared Neighborhood Hits	114
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

SVIL_MOUSE
NC score	0.029912 (rank : 2004)	θ value	0.62314 (rank : 1695)
Query Neighborhood Hits	2923	Target Neighborhood Hits	439	Shared Neighborhood Hits	174
SwissProt Accessions	Q8K4L3	Gene names	Svil
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

RFIP1_HUMAN
NC score	0.029888 (rank : 2005)	θ value	1.38821 (rank : 1878)
Query Neighborhood Hits	2923	Target Neighborhood Hits	236	Shared Neighborhood Hits	113
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

CIR_MOUSE
NC score	0.029874 (rank : 2006)	θ value	0.279714 (rank : 1489)
Query Neighborhood Hits	2923	Target Neighborhood Hits	255	Shared Neighborhood Hits	112
SwissProt Accessions	Q9DA19, Q3V2N9, Q4KL44, Q52KL9, Q5FW66	Gene names	Cir
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor.

SAPS1_HUMAN
NC score	0.029831 (rank : 2007)	θ value	6.88961 (rank : 2687)
Query Neighborhood Hits	2923	Target Neighborhood Hits	704	Shared Neighborhood Hits	253
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

CO002_HUMAN
NC score	0.029783 (rank : 2008)	θ value	5.27518 (rank : 2402)
Query Neighborhood Hits	2923	Target Neighborhood Hits	387	Shared Neighborhood Hits	140
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

SF3A1_MOUSE
NC score	0.029688 (rank : 2009)	θ value	8.99809 (rank : 2877)
Query Neighborhood Hits	2923	Target Neighborhood Hits	198	Shared Neighborhood Hits	113
SwissProt Accessions	Q8K4Z5, Q8C0M7, Q8C128, Q8C175, Q921T3	Gene names	Sf3a1
Domain Architecture	No domain graphic available
Description	Splicing factor 3 subunit 1 (SF3a120).

BRD3_MOUSE
NC score	0.029560 (rank : 2010)	θ value	4.03905 (rank : 2258)
Query Neighborhood Hits	2923	Target Neighborhood Hits	402	Shared Neighborhood Hits	229
SwissProt Accessions	Q8K2F0, Q8C665, Q8CAX7, Q9JI25	Gene names	Brd3, Fsrg2
Domain Architecture
Description	Bromodomain-containing protein 3 (Bromodomain-containing FSH-like protein FSRG2).

ADDA_MOUSE
NC score	0.029526 (rank : 2011)	θ value	0.365318 (rank : 1532)
Query Neighborhood Hits	2923	Target Neighborhood Hits	198	Shared Neighborhood Hits	112
SwissProt Accessions	Q9QYC0, Q9JLE3	Gene names	Add1
Domain Architecture
Description	Alpha-adducin (Erythrocyte adducin subunit alpha).

BAZ2A_HUMAN
NC score	0.029481 (rank : 2012)	θ value	4.03905 (rank : 2256)
Query Neighborhood Hits	2923	Target Neighborhood Hits	780	Shared Neighborhood Hits	332
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

INAR1_HUMAN
NC score	0.029468 (rank : 2013)	θ value	0.279714 (rank : 1508)
Query Neighborhood Hits	2923	Target Neighborhood Hits	49	Shared Neighborhood Hits	29
SwissProt Accessions	P17181, Q53GW9, Q53H11, Q8WTZ2	Gene names	IFNAR1, IFNAR
Domain Architecture	No domain graphic available
Description	Interferon-alpha/beta receptor alpha chain precursor (IFN-alpha-REC).

PKHA5_HUMAN
NC score	0.029465 (rank : 2014)	θ value	0.813845 (rank : 1742)
Query Neighborhood Hits	2923	Target Neighborhood Hits	455	Shared Neighborhood Hits	202
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

SDS3_MOUSE
NC score	0.029414 (rank : 2015)	θ value	1.81305 (rank : 1982)
Query Neighborhood Hits	2923	Target Neighborhood Hits	248	Shared Neighborhood Hits	141
SwissProt Accessions	Q8BR65, Q3UC92, Q6P6K1, Q7TNT0, Q8BRR7, Q8K5B4	Gene names	Suds3, Sds3
Domain Architecture	No domain graphic available
Description	Sin3 histone deacetylase corepressor complex component SDS3 (Suppressor of defective silencing 3 protein homolog).

NHS_HUMAN
NC score	0.029402 (rank : 2016)	θ value	1.38821 (rank : 1868)
Query Neighborhood Hits	2923	Target Neighborhood Hits	198	Shared Neighborhood Hits	92
SwissProt Accessions	Q6T4R5, Q5J7Q0, Q5J7Q1, Q68DR5	Gene names	NHS
Domain Architecture	No domain graphic available
Description	Nance-Horan syndrome protein (Congenital cataracts and dental anomalies protein).

NOP56_HUMAN
NC score	0.029394 (rank : 2017)	θ value	0.0193708 (rank : 1241)
Query Neighborhood Hits	2923	Target Neighborhood Hits	95	Shared Neighborhood Hits	58
SwissProt Accessions	O00567, Q9NQ05	Gene names	NOL5A, NOP56
Domain Architecture
Description	Nucleolar protein Nop56 (Nucleolar protein 5A).

LRC17_HUMAN
NC score	0.029320 (rank : 2018)	θ value	8.99809 (rank : 2824)
Query Neighborhood Hits	2923	Target Neighborhood Hits	267	Shared Neighborhood Hits	66
SwissProt Accessions	Q8N6Y2, Q13288, Q6UWA7, Q75MG5	Gene names	LRRC17, P37NB
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 17 precursor (p37NB).

K0310_HUMAN
NC score	0.029232 (rank : 2019)	θ value	8.99809 (rank : 2805)
Query Neighborhood Hits	2923	Target Neighborhood Hits	420	Shared Neighborhood Hits	150
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

LIRB2_HUMAN
NC score	0.029210 (rank : 2020)	θ value	8.99809 (rank : 2823)
Query Neighborhood Hits	2923	Target Neighborhood Hits	103	Shared Neighborhood Hits	65
SwissProt Accessions	Q8N423, O75017, Q8NHJ7, Q8NHJ8	Gene names	LILRB2, ILT4, LIR2, MIR10
Domain Architecture	No domain graphic available
Description	Leukocyte immunoglobulin-like receptor subfamily B member 2 precursor (Leukocyte immunoglobulin-like receptor 2) (LIR-2) (Immunoglobulin- like transcript 4) (ILT-4) (Monocyte/macrophage immunoglobulin-like receptor 10) (MIR-10) (CD85d antigen).

PPRB_MOUSE
NC score	0.029203 (rank : 2021)	θ value	4.03905 (rank : 2335)
Query Neighborhood Hits	2923	Target Neighborhood Hits	354	Shared Neighborhood Hits	140
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

TAK1L_HUMAN
NC score	0.029156 (rank : 2022)	θ value	2.36792 (rank : 2108)
Query Neighborhood Hits	2923	Target Neighborhood Hits	141	Shared Neighborhood Hits	84
SwissProt Accessions	P57077	Gene names	TAK1L, C21orf7
Domain Architecture	No domain graphic available
Description	TAK1-like protein.

SYGP1_HUMAN
NC score	0.029142 (rank : 2023)	θ value	0.813845 (rank : 1749)
Query Neighborhood Hits	2923	Target Neighborhood Hits	589	Shared Neighborhood Hits	281
SwissProt Accessions	Q96PV0, Q8TCS2, Q9UGE2	Gene names	SYNGAP1, KIAA1938
Domain Architecture
Description	Ras GTPase-activating protein SynGAP (Synaptic Ras-GTPase-activating protein 1) (Synaptic Ras-GAP 1) (Neuronal RasGAP).

GBP4_HUMAN
NC score	0.029051 (rank : 2024)	θ value	6.88961 (rank : 2607)
Query Neighborhood Hits	2923	Target Neighborhood Hits	484	Shared Neighborhood Hits	226
SwissProt Accessions	Q96PP9, Q86T99	Gene names	GBP4
Domain Architecture
Description	Guanylate-binding protein 4 (GTP-binding protein 4) (Guanine nucleotide-binding protein 4) (GBP-4).

BAZ1B_HUMAN
NC score	0.029008 (rank : 2025)	θ value	5.27518 (rank : 2388)
Query Neighborhood Hits	2923	Target Neighborhood Hits	701	Shared Neighborhood Hits	316
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

NOP56_MOUSE
NC score	0.028958 (rank : 2026)	θ value	0.0961366 (rank : 1375)
Query Neighborhood Hits	2923	Target Neighborhood Hits	129	Shared Neighborhood Hits	75
SwissProt Accessions	Q9D6Z1, Q3UD45, Q8BVL1, Q8VDT2, Q99LT8, Q9CT15	Gene names	Nol5a, Nop56
Domain Architecture
Description	Nucleolar protein Nop56 (Nucleolar protein 5A).

HPLN2_HUMAN
NC score	0.028943 (rank : 2027)	θ value	4.03905 (rank : 2288)
Query Neighborhood Hits	2923	Target Neighborhood Hits	80	Shared Neighborhood Hits	59
SwissProt Accessions	Q9GZV7	Gene names	HAPLN2, BRAL1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 2 precursor (Brain link protein 1).

GBP1_HUMAN
NC score	0.028903 (rank : 2028)	θ value	2.36792 (rank : 2048)
Query Neighborhood Hits	2923	Target Neighborhood Hits	339	Shared Neighborhood Hits	199
SwissProt Accessions	P32455	Gene names	GBP1
Domain Architecture
Description	Interferon-induced guanylate-binding protein 1 (GTP-binding protein 1) (Guanine nucleotide-binding protein 1) (GBP-1) (HuGBP-1).

WASF2_HUMAN
NC score	0.028714 (rank : 2029)	θ value	8.99809 (rank : 2913)
Query Neighborhood Hits	2923	Target Neighborhood Hits	280	Shared Neighborhood Hits	139
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

CS029_HUMAN
NC score	0.028621 (rank : 2030)	θ value	8.99809 (rank : 2758)
Query Neighborhood Hits	2923	Target Neighborhood Hits	329	Shared Neighborhood Hits	182
SwissProt Accessions	Q8WUQ7, O75229, Q7LE08, Q9BTA6, Q9Y5A4	Gene names	C19orf29
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 (NY-REN-24 antigen).

NUP88_MOUSE
NC score	0.028606 (rank : 2031)	θ value	3.0926 (rank : 2202)
Query Neighborhood Hits	2923	Target Neighborhood Hits	239	Shared Neighborhood Hits	141
SwissProt Accessions	Q8CEC0, Q80Z13, Q8K090	Gene names	Nup88
Domain Architecture	No domain graphic available
Description	Nuclear pore complex protein Nup88 (Nucleoporin Nup88) (88 kDa nuclear pore complex protein).

IF4G1_MOUSE
NC score	0.028541 (rank : 2032)	θ value	0.0563607 (rank : 1314)
Query Neighborhood Hits	2923	Target Neighborhood Hits	534	Shared Neighborhood Hits	189
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

EMIL2_MOUSE
NC score	0.028510 (rank : 2033)	θ value	5.27518 (rank : 2418)
Query Neighborhood Hits	2923	Target Neighborhood Hits	485	Shared Neighborhood Hits	226
SwissProt Accessions	Q8K482	Gene names	Emilin2
Domain Architecture
Description	EMILIN-2 precursor (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Basilin).

ENAM_HUMAN
NC score	0.028498 (rank : 2034)	θ value	0.0961366 (rank : 1361)
Query Neighborhood Hits	2923	Target Neighborhood Hits	227	Shared Neighborhood Hits	93
SwissProt Accessions	Q9NRM1, Q9H3D1	Gene names	ENAM
Domain Architecture
Description	Enamelin precursor.

SGIP1_HUMAN
NC score	0.028478 (rank : 2035)	θ value	8.99809 (rank : 2879)
Query Neighborhood Hits	2923	Target Neighborhood Hits	198	Shared Neighborhood Hits	94
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

ARI5B_HUMAN
NC score	0.028425 (rank : 2036)	θ value	0.365318 (rank : 1534)
Query Neighborhood Hits	2923	Target Neighborhood Hits	328	Shared Neighborhood Hits	167
SwissProt Accessions	Q14865, Q7Z3M4, Q8N421, Q9H786	Gene names	ARID5B, DESRT, MRF2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (Mrf1-like) (Modulator recognition factor 2) (MRF-2).

TRI46_MOUSE
NC score	0.028408 (rank : 2037)	θ value	0.0193708 (rank : 1245)
Query Neighborhood Hits	2923	Target Neighborhood Hits	287	Shared Neighborhood Hits	85
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

ELOA1_HUMAN
NC score	0.028396 (rank : 2038)	θ value	1.81305 (rank : 1931)
Query Neighborhood Hits	2923	Target Neighborhood Hits	388	Shared Neighborhood Hits	150
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

EMIL2_HUMAN
NC score	0.028395 (rank : 2039)	θ value	4.03905 (rank : 2277)
Query Neighborhood Hits	2923	Target Neighborhood Hits	573	Shared Neighborhood Hits	262
SwissProt Accessions	Q9BXX0, Q8NBH3, Q96JQ4	Gene names	EMILIN2
Domain Architecture
Description	EMILIN-2 precursor (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Protein FOAP-10).

BAT3_MOUSE
NC score	0.028376 (rank : 2040)	θ value	0.813845 (rank : 1706)
Query Neighborhood Hits	2923	Target Neighborhood Hits	518	Shared Neighborhood Hits	179
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

FMN1A_MOUSE
NC score	0.028370 (rank : 2041)	θ value	8.99809 (rank : 2782)
Query Neighborhood Hits	2923	Target Neighborhood Hits	423	Shared Neighborhood Hits	206
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

LMNA_HUMAN
NC score	0.028332 (rank : 2042)	θ value	0.47712 (rank : 1611)
Query Neighborhood Hits	2923	Target Neighborhood Hits	653	Shared Neighborhood Hits	299
SwissProt Accessions	P02545, P02546, Q969I8, Q96JA2	Gene names	LMNA, LMN1
Domain Architecture
Description	Lamin-A/C (70 kDa lamin) (NY-REN-32 antigen).

LIRB1_HUMAN
NC score	0.028330 (rank : 2043)	θ value	0.21417 (rank : 1470)
Query Neighborhood Hits	2923	Target Neighborhood Hits	116	Shared Neighborhood Hits	65
SwissProt Accessions	Q8NHL6, O75024, O75025, Q8NHJ9, Q8NHK0	Gene names	LILRB1, ILT2, LIR1, MIR7
Domain Architecture	No domain graphic available
Description	Leukocyte immunoglobulin-like receptor subfamily B member 1 precursor (Leukocyte immunoglobulin-like receptor 1) (LIR-1) (Immunoglobulin- like transcript 2) (ILT-2) (Monocyte/macrophage immunoglobulin-like receptor 7) (MIR-7) (CD85j antigen).

FMNL_MOUSE
NC score	0.028322 (rank : 2044)	θ value	2.36792 (rank : 2047)
Query Neighborhood Hits	2923	Target Neighborhood Hits	428	Shared Neighborhood Hits	230
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

INAR1_MOUSE
NC score	0.028222 (rank : 2045)	θ value	0.163984 (rank : 1422)
Query Neighborhood Hits	2923	Target Neighborhood Hits	36	Shared Neighborhood Hits	21
SwissProt Accessions	P33896	Gene names	Ifnar1, Ifar, Ifnar
Domain Architecture	No domain graphic available
Description	Interferon-alpha/beta receptor alpha chain precursor (IFN-alpha-REC).

LIRB4_HUMAN
NC score	0.028185 (rank : 2046)	θ value	0.62314 (rank : 1677)
Query Neighborhood Hits	2923	Target Neighborhood Hits	111	Shared Neighborhood Hits	72
SwissProt Accessions	Q8NHJ6, O15468, O75021, Q8N1C7, Q8NHL5	Gene names	LILRB4, ILT3, LIR5
Domain Architecture	No domain graphic available
Description	Leukocyte immunoglobulin-like receptor subfamily B member 4 precursor (Leukocyte immunoglobulin-like receptor 5) (LIR-5) (Immunoglobulin- like transcript 3) (ILT-3) (Monocyte inhibitory receptor HM18) (CD85k antigen).

LMNA_MOUSE
NC score	0.028139 (rank : 2047)	θ value	0.62314 (rank : 1678)
Query Neighborhood Hits	2923	Target Neighborhood Hits	661	Shared Neighborhood Hits	301
SwissProt Accessions	P48678, P11516, P97859, Q3TIH0, Q3TTS8, Q3UCA0, Q3UCJ8, Q91WF2, Q9DC21	Gene names	Lmna, Lmn1
Domain Architecture
Description	Lamin-A/C.

GBP1_MOUSE
NC score	0.028052 (rank : 2048)	θ value	0.365318 (rank : 1550)
Query Neighborhood Hits	2923	Target Neighborhood Hits	302	Shared Neighborhood Hits	167
SwissProt Accessions	Q01514	Gene names	Gbp1, Gbp-1, Mag-1, Mpa1
Domain Architecture
Description	Interferon-induced guanylate-binding protein 1 (GTP-binding protein 1) (Guanine nucleotide-binding protein 1) (GBP-1) (mGBP1) (mGBP-1) (Interferon-gamma-inducible protein MAG-1).

FANK1_MOUSE
NC score	0.027907 (rank : 2049)	θ value	0.00390308 (rank : 1137)
Query Neighborhood Hits	2923	Target Neighborhood Hits	325	Shared Neighborhood Hits	82
SwissProt Accessions	Q9DAM9, Q9CUA7	Gene names	Fank1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains 1 protein (Germ cell- specific gene 1 protein) (GSG1).

TRI46_HUMAN
NC score	0.027904 (rank : 2050)	θ value	0.0193708 (rank : 1244)
Query Neighborhood Hits	2923	Target Neighborhood Hits	291	Shared Neighborhood Hits	85
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

KIF14_HUMAN
NC score	0.027808 (rank : 2051)	θ value	1.38821 (rank : 1857)
Query Neighborhood Hits	2923	Target Neighborhood Hits	732	Shared Neighborhood Hits	345
SwissProt Accessions	Q15058	Gene names	KIF14, KIAA0042
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF14.

DCP1A_HUMAN
NC score	0.027801 (rank : 2052)	θ value	1.38821 (rank : 1837)
Query Neighborhood Hits	2923	Target Neighborhood Hits	228	Shared Neighborhood Hits	107
SwissProt Accessions	Q9NPI6	Gene names	DCP1A, SMIF
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (Smad4-interacting transcriptional co-activator).

SF01_MOUSE
NC score	0.027693 (rank : 2053)	θ value	5.27518 (rank : 2510)
Query Neighborhood Hits	2923	Target Neighborhood Hits	240	Shared Neighborhood Hits	112
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

CD8A_MOUSE
NC score	0.027652 (rank : 2054)	θ value	1.06291 (rank : 1770)
Query Neighborhood Hits	2923	Target Neighborhood Hits	41	Shared Neighborhood Hits	23
SwissProt Accessions	P01731	Gene names	Cd8a, Lyt-2, Lyt2
Domain Architecture
Description	T-cell surface glycoprotein CD8 alpha chain precursor (T-cell surface glycoprotein Lyt-2) (CD8a antigen).

PSL1_HUMAN
NC score	0.027469 (rank : 2055)	θ value	0.813845 (rank : 1743)
Query Neighborhood Hits	2923	Target Neighborhood Hits	650	Shared Neighborhood Hits	210
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

SMCA4_HUMAN
NC score	0.027401 (rank : 2056)	θ value	1.38821 (rank : 1888)
Query Neighborhood Hits	2923	Target Neighborhood Hits	597	Shared Neighborhood Hits	284
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

WASF1_HUMAN
NC score	0.027334 (rank : 2057)	θ value	5.27518 (rank : 2530)
Query Neighborhood Hits	2923	Target Neighborhood Hits	260	Shared Neighborhood Hits	142
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

SNIP_HUMAN
NC score	0.027269 (rank : 2058)	θ value	1.81305 (rank : 1985)
Query Neighborhood Hits	2923	Target Neighborhood Hits	313	Shared Neighborhood Hits	164
SwissProt Accessions	Q9C0H9, Q8N4W8	Gene names	P140, KIAA1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

KI21A_MOUSE
NC score	0.027268 (rank : 2059)	θ value	3.0926 (rank : 2179)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1317	Shared Neighborhood Hits	463
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

TRIM1_HUMAN
NC score	0.027245 (rank : 2060)	θ value	0.0431538 (rank : 1298)
Query Neighborhood Hits	2923	Target Neighborhood Hits	345	Shared Neighborhood Hits	111
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

FANK1_HUMAN
NC score	0.027092 (rank : 2061)	θ value	0.0113563 (rank : 1199)
Query Neighborhood Hits	2923	Target Neighborhood Hits	326	Shared Neighborhood Hits	77
SwissProt Accessions	Q8TC84, Q6UXY9, Q6X7T6	Gene names	FANK1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains protein 1.

SYTL2_HUMAN
NC score	0.027026 (rank : 2062)	θ value	1.43324e-05 (rank : 942)
Query Neighborhood Hits	2923	Target Neighborhood Hits	248	Shared Neighborhood Hits	81
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

PGCA_MOUSE
NC score	0.026992 (rank : 2063)	θ value	0.47712 (rank : 1623)
Query Neighborhood Hits	2923	Target Neighborhood Hits	643	Shared Neighborhood Hits	198
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

ZN638_HUMAN
NC score	0.026966 (rank : 2064)	θ value	0.813845 (rank : 1764)
Query Neighborhood Hits	2923	Target Neighborhood Hits	343	Shared Neighborhood Hits	163
SwissProt Accessions	Q14966, Q53R34, Q5XJ05, Q68DP3, Q6P2H2, Q7Z3T7, Q8NF92, Q8TCA1, Q9H2G1, Q9NP37	Gene names	ZNF638, NP220, ZFML
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein) (Cutaneous T-cell lymphoma-associated antigen se33-1) (CTCL tumor antigen se33-1).

DACT1_HUMAN
NC score	0.026904 (rank : 2065)	θ value	0.62314 (rank : 1660)
Query Neighborhood Hits	2923	Target Neighborhood Hits	228	Shared Neighborhood Hits	102
SwissProt Accessions	Q9NYF0, Q86TY0	Gene names	DACT1, DPR1, HNG3
Domain Architecture	No domain graphic available
Description	Dapper homolog 1 (hDPR1) (Heptacellular carcinoma novel gene 3 protein).

BRD3_HUMAN
NC score	0.026883 (rank : 2066)	θ value	5.27518 (rank : 2391)
Query Neighborhood Hits	2923	Target Neighborhood Hits	369	Shared Neighborhood Hits	212
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

BAZ2A_MOUSE
NC score	0.026835 (rank : 2067)	θ value	3.0926 (rank : 2130)
Query Neighborhood Hits	2923	Target Neighborhood Hits	744	Shared Neighborhood Hits	305
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

ALO17_HUMAN
NC score	0.026813 (rank : 2068)	θ value	6.88961 (rank : 2546)
Query Neighborhood Hits	2923	Target Neighborhood Hits	317	Shared Neighborhood Hits	118
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

RTN1_MOUSE
NC score	0.026762 (rank : 2069)	θ value	1.81305 (rank : 1979)
Query Neighborhood Hits	2923	Target Neighborhood Hits	189	Shared Neighborhood Hits	88
SwissProt Accessions	Q8K0T0, Q8K4S4	Gene names	Rtn1, Nsp
Domain Architecture	No domain graphic available
Description	Reticulon-1 (Neuroendocrine-specific protein).

GON4L_HUMAN
NC score	0.026713 (rank : 2070)	θ value	1.06291 (rank : 1780)
Query Neighborhood Hits	2923	Target Neighborhood Hits	555	Shared Neighborhood Hits	233
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

JPH2_HUMAN
NC score	0.026673 (rank : 2071)	θ value	1.81305 (rank : 1947)
Query Neighborhood Hits	2923	Target Neighborhood Hits	639	Shared Neighborhood Hits	223
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

TRI36_HUMAN
NC score	0.026672 (rank : 2072)	θ value	0.0431538 (rank : 1296)
Query Neighborhood Hits	2923	Target Neighborhood Hits	282	Shared Neighborhood Hits	93
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

ZN365_MOUSE
NC score	0.026626 (rank : 2073)	θ value	0.365318 (rank : 1577)
Query Neighborhood Hits	2923	Target Neighborhood Hits	193	Shared Neighborhood Hits	115
SwissProt Accessions	Q8BG89, Q80TQ4, Q8BK39, Q8BXT2	Gene names	Znf365, Kiaa0844, Zfp365
Domain Architecture	No domain graphic available
Description	Protein ZNF365 (Su48).

TIMD4_HUMAN
NC score	0.026619 (rank : 2074)	θ value	0.0961366 (rank : 1380)
Query Neighborhood Hits	2923	Target Neighborhood Hits	55	Shared Neighborhood Hits	35
SwissProt Accessions	Q96H15	Gene names	TIMD4, TIM4
Domain Architecture	No domain graphic available
Description	T-cell immunoglobulin and mucin domain-containing protein 4 precursor (TIMD-4) (T-cell membrane protein 4) (TIM-4).

AAT1_HUMAN
NC score	0.026550 (rank : 2075)	θ value	4.03905 (rank : 2246)
Query Neighborhood Hits	2923	Target Neighborhood Hits	199	Shared Neighborhood Hits	128
SwissProt Accessions	Q7Z4T9, Q68DX2, Q8TD41, Q96A45, Q96JE8	Gene names	AAT1, C3orf15
Domain Architecture	No domain graphic available
Description	AMY-1-associating protein expressed in testis 1 (AAT-1).

PKCB1_HUMAN
NC score	0.026486 (rank : 2076)	θ value	3.0926 (rank : 2208)
Query Neighborhood Hits	2923	Target Neighborhood Hits	488	Shared Neighborhood Hits	205
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

ZC11A_MOUSE
NC score	0.026459 (rank : 2077)	θ value	0.813845 (rank : 1762)
Query Neighborhood Hits	2923	Target Neighborhood Hits	216	Shared Neighborhood Hits	111
SwissProt Accessions	Q6NZF1, Q6NXW9, Q6PDR6, Q80TU7, Q8C5L5, Q99JN6	Gene names	Zc3h11a, Kiaa0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

EGFL9_HUMAN
NC score	0.026401 (rank : 2078)	θ value	3.0926 (rank : 2160)
Query Neighborhood Hits	2923	Target Neighborhood Hits	365	Shared Neighborhood Hits	62
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

BT2A1_HUMAN
NC score	0.026355 (rank : 2079)	θ value	0.0563607 (rank : 1303)
Query Neighborhood Hits	2923	Target Neighborhood Hits	185	Shared Neighborhood Hits	98
SwissProt Accessions	Q7KYR7, O00475, P78408, Q7KYQ7, Q7Z386, Q9NU62	Gene names	BTN2A1, BT2.1, BTF1
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A1 precursor.

GBP2_MOUSE
NC score	0.026333 (rank : 2080)	θ value	6.88961 (rank : 2606)
Query Neighborhood Hits	2923	Target Neighborhood Hits	323	Shared Neighborhood Hits	182
SwissProt Accessions	Q9Z0E6, Q8CIC6, Q921N2, Q9R1I0	Gene names	Gbp2
Domain Architecture
Description	Interferon-induced guanylate-binding protein 2 (GTP-binding protein 2) (Guanine nucleotide-binding protein 2) (GBP-2) (mGBP2) (mGBP-2).

ASXL1_HUMAN
NC score	0.026317 (rank : 2081)	θ value	0.62314 (rank : 1650)
Query Neighborhood Hits	2923	Target Neighborhood Hits	260	Shared Neighborhood Hits	98
SwissProt Accessions	Q8IXJ9, Q5JWS9, Q8IYY7, Q9H466, Q9NQF8, Q9UFJ0, Q9UFP8, Q9Y2I4	Gene names	ASXL1, KIAA0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

A20A4_HUMAN
NC score	0.026272 (rank : 2082)	θ value	5.27518 (rank : 2377)
Query Neighborhood Hits	2923	Target Neighborhood Hits	710	Shared Neighborhood Hits	256
SwissProt Accessions	Q5SQ80	Gene names	ANKRD20A4
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A4.

KIFC1_HUMAN
NC score	0.026238 (rank : 2083)	θ value	3.0926 (rank : 2180)
Query Neighborhood Hits	2923	Target Neighborhood Hits	545	Shared Neighborhood Hits	262
SwissProt Accessions	Q9BW19, O60887, Q14834, Q9UQP7	Gene names	KIFC1, HSET, KNSL2
Domain Architecture
Description	Kinesin-like protein KIFC1 (Kinesin-like protein 2) (Kinesin-related protein HSET).

OLR1_MOUSE
NC score	0.026132 (rank : 2084)	θ value	8.99809 (rank : 2846)
Query Neighborhood Hits	2923	Target Neighborhood Hits	596	Shared Neighborhood Hits	241
SwissProt Accessions	Q9EQ09	Gene names	Olr1, Lox1
Domain Architecture	No domain graphic available
Description	Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1) (Lectin-type oxidized LDL receptor 1) (Lectin-like oxidized LDL receptor 1) (Lectin-like oxLDL receptor 1) (LOX-1) [Contains: Oxidized low-density lipoprotein receptor 1, soluble form].

I20RA_MOUSE
NC score	0.026111 (rank : 2085)	θ value	0.0736092 (rank : 1338)
Query Neighborhood Hits	2923	Target Neighborhood Hits	37	Shared Neighborhood Hits	19
SwissProt Accessions	Q6PHB0, Q8BW64	Gene names	Il20ra
Domain Architecture	No domain graphic available
Description	Interleukin-20 receptor alpha chain precursor (IL-20R-alpha) (IL- 20R1).

ADDB_HUMAN
NC score	0.026072 (rank : 2086)	θ value	0.47712 (rank : 1583)
Query Neighborhood Hits	2923	Target Neighborhood Hits	142	Shared Neighborhood Hits	72
SwissProt Accessions	P35612, Q13482, Q16412, Q59G82, Q5U5P4, Q6P0P2, Q6PGQ4, Q7Z688, Q7Z689, Q7Z690, Q7Z691	Gene names	ADD2, ADDB
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta).

RBP1_HUMAN
NC score	0.026015 (rank : 2087)	θ value	1.38821 (rank : 1876)
Query Neighborhood Hits	2923	Target Neighborhood Hits	521	Shared Neighborhood Hits	230
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

A20A1_HUMAN
NC score	0.025981 (rank : 2088)	θ value	5.27518 (rank : 2374)
Query Neighborhood Hits	2923	Target Neighborhood Hits	698	Shared Neighborhood Hits	249
SwissProt Accessions	Q5TYW2, Q9H0H6	Gene names	ANKRD20A1, ANKRD20A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A1.

CA049_MOUSE
NC score	0.025949 (rank : 2089)	θ value	1.38821 (rank : 1823)
Query Neighborhood Hits	2923	Target Neighborhood Hits	121	Shared Neighborhood Hits	82
SwissProt Accessions	Q14BK3, Q4KKY9, Q9D9J9	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf49 homolog.

EGFL9_MOUSE
NC score	0.025878 (rank : 2090)	θ value	3.0926 (rank : 2161)
Query Neighborhood Hits	2923	Target Neighborhood Hits	379	Shared Neighborhood Hits	65
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

REXO1_HUMAN
NC score	0.025869 (rank : 2091)	θ value	6.88961 (rank : 2681)
Query Neighborhood Hits	2923	Target Neighborhood Hits	242	Shared Neighborhood Hits	121
SwissProt Accessions	Q8N1G1, Q9ULT2	Gene names	REXO1, ELOABP1, KIAA1138, TCEB3BP1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Elongin A-binding protein 1) (EloA-BP1) (Transcription elongation factor B polypeptide 3-binding protein 1).

HPLN3_MOUSE
NC score	0.025795 (rank : 2092)	θ value	0.163984 (rank : 1420)
Query Neighborhood Hits	2923	Target Neighborhood Hits	95	Shared Neighborhood Hits	75
SwissProt Accessions	Q80WM5, Q80XX3	Gene names	Hapln3, Lpr3
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 3 precursor (Link protein 3).

LEUK_HUMAN
NC score	0.025756 (rank : 2093)	θ value	2.36792 (rank : 2076)
Query Neighborhood Hits	2923	Target Neighborhood Hits	213	Shared Neighborhood Hits	90
SwissProt Accessions	P16150	Gene names	SPN, CD43
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Galactoglycoprotein) (GALGP) (CD43 antigen).

BIN1_MOUSE
NC score	0.025689 (rank : 2094)	θ value	1.06291 (rank : 1767)
Query Neighborhood Hits	2923	Target Neighborhood Hits	283	Shared Neighborhood Hits	108
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

POT15_HUMAN
NC score	0.025666 (rank : 2095)	θ value	0.163984 (rank : 1430)
Query Neighborhood Hits	2923	Target Neighborhood Hits	893	Shared Neighborhood Hits	334
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

LMO7_HUMAN
NC score	0.025645 (rank : 2096)	θ value	0.365318 (rank : 1557)
Query Neighborhood Hits	2923	Target Neighborhood Hits	507	Shared Neighborhood Hits	195
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

BAT3_HUMAN
NC score	0.025577 (rank : 2097)	θ value	0.813845 (rank : 1705)
Query Neighborhood Hits	2923	Target Neighborhood Hits	490	Shared Neighborhood Hits	167
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

A20A2_HUMAN
NC score	0.025568 (rank : 2098)	θ value	5.27518 (rank : 2375)
Query Neighborhood Hits	2923	Target Neighborhood Hits	716	Shared Neighborhood Hits	254
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

A20A3_HUMAN
NC score	0.025562 (rank : 2099)	θ value	5.27518 (rank : 2376)
Query Neighborhood Hits	2923	Target Neighborhood Hits	692	Shared Neighborhood Hits	252
SwissProt Accessions	Q5VUR7	Gene names	ANKRD20A3
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A3.

BTBDC_HUMAN
NC score	0.025550 (rank : 2100)	θ value	3.0926 (rank : 2134)
Query Neighborhood Hits	2923	Target Neighborhood Hits	248	Shared Neighborhood Hits	84
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

TTF1_MOUSE
NC score	0.025435 (rank : 2101)	θ value	6.88961 (rank : 2706)
Query Neighborhood Hits	2923	Target Neighborhood Hits	277	Shared Neighborhood Hits	144
SwissProt Accessions	Q62187, Q9JKK5	Gene names	Ttf1
Domain Architecture	No domain graphic available
Description	Transcription termination factor 1 (TTF-1) (TTF-I) (mTFF-I) (RNA polymerase I termination factor).

EP400_HUMAN
NC score	0.025347 (rank : 2102)	θ value	4.03905 (rank : 2278)
Query Neighborhood Hits	2923	Target Neighborhood Hits	556	Shared Neighborhood Hits	268
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

ATX2_MOUSE
NC score	0.025257 (rank : 2103)	θ value	6.88961 (rank : 2549)
Query Neighborhood Hits	2923	Target Neighborhood Hits	445	Shared Neighborhood Hits	177
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

GFAP_MOUSE
NC score	0.025171 (rank : 2104)	θ value	6.88961 (rank : 2608)
Query Neighborhood Hits	2923	Target Neighborhood Hits	725	Shared Neighborhood Hits	306
SwissProt Accessions	P03995, Q7TQ30, Q925K3	Gene names	Gfap
Domain Architecture
Description	Glial fibrillary acidic protein, astrocyte (GFAP).

SH2D3_HUMAN
NC score	0.025148 (rank : 2105)	θ value	1.38821 (rank : 1885)
Query Neighborhood Hits	2923	Target Neighborhood Hits	188	Shared Neighborhood Hits	62
SwissProt Accessions	Q8N5H7, Q5HYE5, Q6UY42, Q8N6X3, Q9Y2X5	Gene names	SH2D3C, NSP3
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (Novel SH2-containing protein 3).

SCN3B_MOUSE
NC score	0.025025 (rank : 2106)	θ value	4.03905 (rank : 2353)
Query Neighborhood Hits	2923	Target Neighborhood Hits	89	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BHK2, Q91Z99	Gene names	Scn3b
Domain Architecture
Description	Sodium channel beta-3 subunit precursor.

AKAP5_HUMAN
NC score	0.024994 (rank : 2107)	θ value	0.125558 (rank : 1383)
Query Neighborhood Hits	2923	Target Neighborhood Hits	41	Shared Neighborhood Hits	19
SwissProt Accessions	P24588	Gene names	AKAP5, AKAP79
Domain Architecture
Description	A-kinase anchor protein 5 (A-kinase anchor protein 79 kDa) (AKAP 79) (cAMP-dependent protein kinase regulatory subunit II high affinity- binding protein) (H21).

PSIP1_MOUSE
NC score	0.024925 (rank : 2108)	θ value	1.38821 (rank : 1874)
Query Neighborhood Hits	2923	Target Neighborhood Hits	313	Shared Neighborhood Hits	147
SwissProt Accessions	Q99JF8, Q3TEJ7, Q3TTD7, Q3UTA1, Q80WQ7, Q99JF7, Q99LR4, Q9CT03	Gene names	Psip1, Ledgf
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (mLEDGF).

RIF1_MOUSE
NC score	0.024900 (rank : 2109)	θ value	3.0926 (rank : 2218)
Query Neighborhood Hits	2923	Target Neighborhood Hits	315	Shared Neighborhood Hits	145
SwissProt Accessions	Q6PR54, Q6T8D9, Q7TPD8, Q8BTU2, Q8C408, Q9CS77	Gene names	Rif1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog) (mRif1).

EP400_MOUSE
NC score	0.024873 (rank : 2110)	θ value	6.88961 (rank : 2593)
Query Neighborhood Hits	2923	Target Neighborhood Hits	592	Shared Neighborhood Hits	252
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

TCAL5_HUMAN
NC score	0.024834 (rank : 2111)	θ value	0.125558 (rank : 1403)
Query Neighborhood Hits	2923	Target Neighborhood Hits	806	Shared Neighborhood Hits	249
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

SPR2E_MOUSE
NC score	0.024766 (rank : 2112)	θ value	8.99809 (rank : 2887)
Query Neighborhood Hits	2923	Target Neighborhood Hits	45	Shared Neighborhood Hits	19
SwissProt Accessions	O70556	Gene names	Sprr2e
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E.

PORIM_MOUSE
NC score	0.024723 (rank : 2113)	θ value	0.163984 (rank : 1429)
Query Neighborhood Hits	2923	Target Neighborhood Hits	43	Shared Neighborhood Hits	22
SwissProt Accessions	Q91Z22, Q3T9F6, Q3TLL2, Q3U1R6, Q8CEX4	Gene names	Tmem123
Domain Architecture	No domain graphic available
Description	Porimin precursor (Transmembrane protein 123).

GTF2I_HUMAN
NC score	0.024632 (rank : 2114)	θ value	0.000461057 (rank : 1054)
Query Neighborhood Hits	2923	Target Neighborhood Hits	151	Shared Neighborhood Hits	61
SwissProt Accessions	P78347, O14743, O15359, O43546, O43588, O43589, Q9BSZ4	Gene names	GTF2I, BAP135, WBSCR6
Domain Architecture
Description	General transcription factor II-I (GTFII-I) (TFII-I) (Bruton tyrosine kinase-associated protein 135) (BTK-associated protein 135) (BAP-135) (SRF-Phox1-interacting protein) (SPIN) (Williams-Beuren syndrome chromosome region 6 protein).

RBP1_MOUSE
NC score	0.024624 (rank : 2115)	θ value	1.38821 (rank : 1877)
Query Neighborhood Hits	2923	Target Neighborhood Hits	493	Shared Neighborhood Hits	229
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

CT102_MOUSE
NC score	0.024610 (rank : 2116)	θ value	6.88961 (rank : 2577)
Query Neighborhood Hits	2923	Target Neighborhood Hits	46	Shared Neighborhood Hits	30
SwissProt Accessions	Q6PDS0	Gene names	Gm691
Domain Architecture	No domain graphic available
Description	Protein C20orf102 homolog precursor.

HCLS1_HUMAN
NC score	0.024607 (rank : 2117)	θ value	0.125558 (rank : 1390)
Query Neighborhood Hits	2923	Target Neighborhood Hits	358	Shared Neighborhood Hits	140
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

LIRB3_HUMAN
NC score	0.024498 (rank : 2118)	θ value	1.81305 (rank : 1955)
Query Neighborhood Hits	2923	Target Neighborhood Hits	125	Shared Neighborhood Hits	62
SwissProt Accessions	O75022, O15471, Q86U49	Gene names	LILRB3, ILT5, LIR3
Domain Architecture	No domain graphic available
Description	Leukocyte immunoglobulin-like receptor subfamily B member 3 precursor (Leukocyte immunoglobulin-like receptor 3) (LIR-3) (Immunoglobulin- like transcript 5) (ILT-5) (Monocyte inhibitory receptor HL9) (CD85a antigen).

GHR_MOUSE
NC score	0.024479 (rank : 2119)	θ value	0.62314 (rank : 1667)
Query Neighborhood Hits	2923	Target Neighborhood Hits	43	Shared Neighborhood Hits	29
SwissProt Accessions	P16882, P16590, Q61653, Q6DI66, Q80W86, Q8R1M5, Q920Z3, Q9R264	Gene names	Ghr
Domain Architecture
Description	Growth hormone receptor precursor (GH receptor) (Somatotropin receptor) [Contains: Growth hormone-binding protein (GH-binding protein) (GHBP) (Serum-binding protein)].

3BP2_HUMAN
NC score	0.024440 (rank : 2120)	θ value	0.813845 (rank : 1700)
Query Neighborhood Hits	2923	Target Neighborhood Hits	296	Shared Neighborhood Hits	116
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

MEGF8_MOUSE
NC score	0.024440 (rank : 2121)	θ value	8.99809 (rank : 2831)
Query Neighborhood Hits	2923	Target Neighborhood Hits	520	Shared Neighborhood Hits	86
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

K1914_HUMAN
NC score	0.024322 (rank : 2122)	θ value	1.38821 (rank : 1856)
Query Neighborhood Hits	2923	Target Neighborhood Hits	255	Shared Neighborhood Hits	124
SwissProt Accessions	Q8N4X5, Q8TB54, Q96PX4, Q96SY5	Gene names	KIAA1914
Domain Architecture	No domain graphic available
Description	Protein KIAA1914.

IL2RG_MOUSE
NC score	0.024304 (rank : 2123)	θ value	0.47712 (rank : 1606)
Query Neighborhood Hits	2923	Target Neighborhood Hits	42	Shared Neighborhood Hits	25
SwissProt Accessions	P34902	Gene names	Il2rg
Domain Architecture
Description	Cytokine receptor common gamma chain precursor (Gamma-C) (Interleukin- 2 receptor gamma chain) (IL-2R gamma chain) (p64) (CD132 antigen).

SNPC4_MOUSE
NC score	0.024286 (rank : 2124)	θ value	0.21417 (rank : 1476)
Query Neighborhood Hits	2923	Target Neighborhood Hits	237	Shared Neighborhood Hits	111
SwissProt Accessions	Q8BP86, Q6PGG7, Q80UG9, Q810L1	Gene names	Snapc4
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit).

CDT1_MOUSE
NC score	0.024253 (rank : 2125)	θ value	0.279714 (rank : 1487)
Query Neighborhood Hits	2923	Target Neighborhood Hits	72	Shared Neighborhood Hits	39
SwissProt Accessions	Q8R4E9, Q8BUQ1, Q8BX29, Q8R3V0, Q8R4E8	Gene names	Cdt1, Ris2
Domain Architecture	No domain graphic available
Description	DNA replication factor Cdt1 (Double parked homolog) (DUP) (Retroviral insertion site 2 protein).

NP1L3_HUMAN
NC score	0.024225 (rank : 2126)	θ value	0.21417 (rank : 1472)
Query Neighborhood Hits	2923	Target Neighborhood Hits	172	Shared Neighborhood Hits	101
SwissProt Accessions	Q99457, O60788	Gene names	NAP1L3, BNAP
Domain Architecture
Description	Nucleosome assembly protein 1-like 3.

CASL_HUMAN
NC score	0.024143 (rank : 2127)	θ value	0.0330416 (rank : 1264)
Query Neighborhood Hits	2923	Target Neighborhood Hits	259	Shared Neighborhood Hits	85
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

CS007_HUMAN
NC score	0.023987 (rank : 2128)	θ value	6.88961 (rank : 2575)
Query Neighborhood Hits	2923	Target Neighborhood Hits	401	Shared Neighborhood Hits	170
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

ANR21_HUMAN
NC score	0.023934 (rank : 2129)	θ value	0.21417 (rank : 1441)
Query Neighborhood Hits	2923	Target Neighborhood Hits	864	Shared Neighborhood Hits	320
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

SEM3C_MOUSE
NC score	0.023794 (rank : 2130)	θ value	0.00665767 (rank : 1174)
Query Neighborhood Hits	2923	Target Neighborhood Hits	113	Shared Neighborhood Hits	65
SwissProt Accessions	Q62181	Gene names	Sema3c, Semae, SemE
Domain Architecture
Description	Semaphorin-3C precursor (Semaphorin E) (Sema E).

LIRA1_HUMAN
NC score	0.023743 (rank : 2131)	θ value	8.99809 (rank : 2821)
Query Neighborhood Hits	2923	Target Neighborhood Hits	83	Shared Neighborhood Hits	54
SwissProt Accessions	O75019, O75018	Gene names	LILRA1, LIR6
Domain Architecture
Description	Leukocyte immunoglobulin-like receptor subfamily A member 1 precursor (Leukocyte immunoglobulin-like receptor 6) (LIR-6) (CD85i antigen).

SEPT9_MOUSE
NC score	0.023628 (rank : 2132)	θ value	0.000121331 (rank : 1016)
Query Neighborhood Hits	2923	Target Neighborhood Hits	238	Shared Neighborhood Hits	87
SwissProt Accessions	Q80UG5, Q3URP2, Q80TM7, Q9QYX9	Gene names	Sept9, Kiaa0991, Sint1
Domain Architecture	No domain graphic available
Description	Septin-9 (SL3-3 integration site 1 protein).

SMRC2_HUMAN
NC score	0.023625 (rank : 2133)	θ value	8.99809 (rank : 2884)
Query Neighborhood Hits	2923	Target Neighborhood Hits	499	Shared Neighborhood Hits	208
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

YETS2_MOUSE
NC score	0.023575 (rank : 2134)	θ value	0.365318 (rank : 1576)
Query Neighborhood Hits	2923	Target Neighborhood Hits	278	Shared Neighborhood Hits	108
SwissProt Accessions	Q3TUF7, Q6PGF8, Q80TI2, Q8CG86	Gene names	Yeats2, Kiaa1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

NOTC2_HUMAN
NC score	0.023518 (rank : 2135)	θ value	0.813845 (rank : 1736)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1113	Shared Neighborhood Hits	232
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

CT102_HUMAN
NC score	0.023516 (rank : 2136)	θ value	8.99809 (rank : 2760)
Query Neighborhood Hits	2923	Target Neighborhood Hits	42	Shared Neighborhood Hits	32
SwissProt Accessions	Q96N03, Q5JWZ5, Q8ND45, Q9BR37	Gene names	C20orf102
Domain Architecture
Description	Protein C20orf102 precursor.

MAML2_HUMAN
NC score	0.023513 (rank : 2137)	θ value	4.03905 (rank : 2314)
Query Neighborhood Hits	2923	Target Neighborhood Hits	360	Shared Neighborhood Hits	152
SwissProt Accessions	Q8IZL2, Q6AI23, Q6Y3A3, Q8IUL3, Q96JK6	Gene names	MAML2, KIAA1819
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 2 (Mam-2).

IGHD_HUMAN
NC score	0.023395 (rank : 2138)	θ value	6.88961 (rank : 2624)
Query Neighborhood Hits	2923	Target Neighborhood Hits	194	Shared Neighborhood Hits	59
SwissProt Accessions	P01880	Gene names	IGHD
Domain Architecture	No domain graphic available
Description	Ig delta chain C region.

CEL_HUMAN
NC score	0.023362 (rank : 2139)	θ value	0.00102713 (rank : 1079)
Query Neighborhood Hits	2923	Target Neighborhood Hits	896	Shared Neighborhood Hits	271
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

GP158_HUMAN
NC score	0.023342 (rank : 2140)	θ value	1.38821 (rank : 1846)
Query Neighborhood Hits	2923	Target Neighborhood Hits	221	Shared Neighborhood Hits	92
SwissProt Accessions	Q5T848, Q6QR81, Q9ULT3	Gene names	GPR158, KIAA1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

DNL1_MOUSE
NC score	0.023322 (rank : 2141)	θ value	1.81305 (rank : 1928)
Query Neighborhood Hits	2923	Target Neighborhood Hits	110	Shared Neighborhood Hits	70
SwissProt Accessions	P37913	Gene names	Lig1, Lig-1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

I20RA_HUMAN
NC score	0.023298 (rank : 2142)	θ value	0.00665767 (rank : 1166)
Query Neighborhood Hits	2923	Target Neighborhood Hits	39	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UHF4, Q6UWA9, Q96SH8	Gene names	IL20RA, ZCYTOR7
Domain Architecture	No domain graphic available
Description	Interleukin-20 receptor alpha chain precursor (IL-20R-alpha) (IL-20R1) (Cytokine receptor family 2 member 8) (Cytokine receptor class-II member 8) (CRF2-8) (ZcytoR7).

PSIP1_HUMAN
NC score	0.023189 (rank : 2143)	θ value	1.81305 (rank : 1972)
Query Neighborhood Hits	2923	Target Neighborhood Hits	341	Shared Neighborhood Hits	157
SwissProt Accessions	O75475, O00256, O95368, Q6P391, Q86YB9, Q9NZI3, Q9UER6	Gene names	PSIP1, DFS70, LEDGF, PSIP2
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (Transcriptional coactivator p75/p52) (Dense fine speckles 70 kDa protein) (DFS 70) (CLL-associated antigen KW-7).

BTLA_MOUSE
NC score	0.023182 (rank : 2144)	θ value	5.27518 (rank : 2393)
Query Neighborhood Hits	2923	Target Neighborhood Hits	19	Shared Neighborhood Hits	18
SwissProt Accessions	Q7TSA3	Gene names	Btla
Domain Architecture	No domain graphic available
Description	B- and T-lymphocyte attenuator precursor (B- and T-lymphocyte- associated protein) (CD272 antigen).

HCLS1_MOUSE
NC score	0.023053 (rank : 2145)	θ value	1.38821 (rank : 1849)
Query Neighborhood Hits	2923	Target Neighborhood Hits	329	Shared Neighborhood Hits	131
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

PDCD1_HUMAN
NC score	0.022997 (rank : 2146)	θ value	0.47712 (rank : 1622)
Query Neighborhood Hits	2923	Target Neighborhood Hits	106	Shared Neighborhood Hits	46
SwissProt Accessions	Q15116, O00517	Gene names	PDCD1, PD1
Domain Architecture
Description	Programmed cell death protein 1 precursor (Protein PD-1) (hPD-1) (CD279 antigen).

OBF1_MOUSE
NC score	0.022969 (rank : 2147)	θ value	0.813845 (rank : 1737)
Query Neighborhood Hits	2923	Target Neighborhood Hits	73	Shared Neighborhood Hits	27
SwissProt Accessions	Q64693	Gene names	Pou2af1, Obf-1
Domain Architecture	No domain graphic available
Description	POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (OCT-binding factor 1) (BOB-1) (BOB1) (OCA-B).

SETD2_HUMAN
NC score	0.022912 (rank : 2148)	θ value	0.62314 (rank : 1692)
Query Neighborhood Hits	2923	Target Neighborhood Hits	412	Shared Neighborhood Hits	180
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

DMN_HUMAN
NC score	0.022883 (rank : 2149)	θ value	1.81305 (rank : 1927)
Query Neighborhood Hits	2923	Target Neighborhood Hits	690	Shared Neighborhood Hits	311
SwissProt Accessions	O15061	Gene names	DMN, KIAA0353
Domain Architecture
Description	Desmuslin.

IGHE_MOUSE
NC score	0.022869 (rank : 2150)	θ value	2.36792 (rank : 2059)
Query Neighborhood Hits	2923	Target Neighborhood Hits	209	Shared Neighborhood Hits	54
SwissProt Accessions	P06336, P01856	Gene names
Domain Architecture
Description	Ig epsilon chain C region.

SAFB1_HUMAN
NC score	0.022795 (rank : 2151)	θ value	6.88961 (rank : 2686)
Query Neighborhood Hits	2923	Target Neighborhood Hits	493	Shared Neighborhood Hits	179
SwissProt Accessions	Q15424, O60406, Q59HH8	Gene names	SAFB, HAP, HET, SAFB1
Domain Architecture
Description	Scaffold attachment factor B (Scaffold attachment factor B1) (SAF-B) (HSP27 estrogen response element-TATA box-binding protein) (HSP27 ERE- TATA-binding protein).

ASXL1_MOUSE
NC score	0.022757 (rank : 2152)	θ value	0.0736092 (rank : 1326)
Query Neighborhood Hits	2923	Target Neighborhood Hits	182	Shared Neighborhood Hits	78
SwissProt Accessions	P59598	Gene names	Asxl1, Kiaa0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

TRI66_MOUSE
NC score	0.022748 (rank : 2153)	θ value	0.21417 (rank : 1480)
Query Neighborhood Hits	2923	Target Neighborhood Hits	491	Shared Neighborhood Hits	210
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

NOTC2_MOUSE
NC score	0.022705 (rank : 2154)	θ value	1.81305 (rank : 1962)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1069	Shared Neighborhood Hits	207
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

PALM_MOUSE
NC score	0.022628 (rank : 2155)	θ value	6.88961 (rank : 2667)
Query Neighborhood Hits	2923	Target Neighborhood Hits	228	Shared Neighborhood Hits	123
SwissProt Accessions	Q9Z0P4, Q9Z0P3	Gene names	Palm
Domain Architecture
Description	Paralemmin.

SETD8_MOUSE
NC score	0.022610 (rank : 2156)	θ value	0.125558 (rank : 1399)
Query Neighborhood Hits	2923	Target Neighborhood Hits	131	Shared Neighborhood Hits	68
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).

CD79A_MOUSE
NC score	0.022523 (rank : 2157)	θ value	2.36792 (rank : 2025)
Query Neighborhood Hits	2923	Target Neighborhood Hits	17	Shared Neighborhood Hits	16
SwissProt Accessions	P11911	Gene names	Cd79a, Iga, Mb-1
Domain Architecture
Description	B-cell antigen receptor complex-associated protein alpha-chain precursor (IG-alpha) (MB-1 membrane glycoprotein) (Surface IgM- associated protein) (Membrane-bound immunoglobulin-associated protein) (CD79a antigen).

CENPQ_MOUSE
NC score	0.022412 (rank : 2158)	θ value	2.36792 (rank : 2029)
Query Neighborhood Hits	2923	Target Neighborhood Hits	160	Shared Neighborhood Hits	100
SwissProt Accessions	Q9CPQ5, Q8C2G4, Q8VEF8, Q9CX70	Gene names	Cenpq
Domain Architecture	No domain graphic available
Description	Centromere protein Q (CENP-Q).

NP1L3_MOUSE
NC score	0.022367 (rank : 2159)	θ value	1.81305 (rank : 1963)
Query Neighborhood Hits	2923	Target Neighborhood Hits	233	Shared Neighborhood Hits	114
SwissProt Accessions	Q794H2, O54802	Gene names	Nap1l3, Mb20
Domain Architecture	No domain graphic available
Description	Nucleosome assembly protein 1-like 3 (Brain-specific protein MB20).

PHF3_HUMAN
NC score	0.022342 (rank : 2160)	θ value	1.38821 (rank : 1871)
Query Neighborhood Hits	2923	Target Neighborhood Hits	419	Shared Neighborhood Hits	164
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

RP3A_MOUSE
NC score	0.022290 (rank : 2161)	θ value	0.62314 (rank : 1688)
Query Neighborhood Hits	2923	Target Neighborhood Hits	510	Shared Neighborhood Hits	165
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

ZN365_HUMAN
NC score	0.022289 (rank : 2162)	θ value	6.88961 (rank : 2717)
Query Neighborhood Hits	2923	Target Neighborhood Hits	145	Shared Neighborhood Hits	82
SwissProt Accessions	Q70YC5, O94930, Q5HYE6, Q68SG8, Q6NSK2, Q6P9D4, Q70YC6, Q70YC7	Gene names	ZNF365, KIAA0844
Domain Architecture	No domain graphic available
Description	Protein ZNF365.

MYST4_HUMAN
NC score	0.022275 (rank : 2163)	θ value	6.88961 (rank : 2655)
Query Neighborhood Hits	2923	Target Neighborhood Hits	671	Shared Neighborhood Hits	285
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

GP158_MOUSE
NC score	0.022268 (rank : 2164)	θ value	0.000461057 (rank : 1053)
Query Neighborhood Hits	2923	Target Neighborhood Hits	82	Shared Neighborhood Hits	24
SwissProt Accessions	Q8C419, Q8CHB0	Gene names	Gpr158, Kiaa1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

PDZD2_HUMAN
NC score	0.022261 (rank : 2165)	θ value	3.0926 (rank : 2204)
Query Neighborhood Hits	2923	Target Neighborhood Hits	772	Shared Neighborhood Hits	235
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

UBP8_HUMAN
NC score	0.022218 (rank : 2166)	θ value	0.21417 (rank : 1481)
Query Neighborhood Hits	2923	Target Neighborhood Hits	751	Shared Neighborhood Hits	345
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

RAI1_HUMAN
NC score	0.022180 (rank : 2167)	θ value	0.47712 (rank : 1626)
Query Neighborhood Hits	2923	Target Neighborhood Hits	360	Shared Neighborhood Hits	137
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

IF4B_MOUSE
NC score	0.022066 (rank : 2168)	θ value	0.0736092 (rank : 1340)
Query Neighborhood Hits	2923	Target Neighborhood Hits	368	Shared Neighborhood Hits	118
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

ZO1_HUMAN
NC score	0.022041 (rank : 2169)	θ value	5.27518 (rank : 2539)
Query Neighborhood Hits	2923	Target Neighborhood Hits	474	Shared Neighborhood Hits	181
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ETV3_HUMAN
NC score	0.021976 (rank : 2170)	θ value	0.00020696 (rank : 1031)
Query Neighborhood Hits	2923	Target Neighborhood Hits	312	Shared Neighborhood Hits	135
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

RAI1_MOUSE
NC score	0.021853 (rank : 2171)	θ value	2.36792 (rank : 2094)
Query Neighborhood Hits	2923	Target Neighborhood Hits	344	Shared Neighborhood Hits	129
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

CD248_MOUSE
NC score	0.021578 (rank : 2172)	θ value	0.0961366 (rank : 1359)
Query Neighborhood Hits	2923	Target Neighborhood Hits	578	Shared Neighborhood Hits	165
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

VPS72_MOUSE
NC score	0.021452 (rank : 2173)	θ value	0.813845 (rank : 1760)
Query Neighborhood Hits	2923	Target Neighborhood Hits	286	Shared Neighborhood Hits	104
SwissProt Accessions	Q62481, Q3U2N4, Q810A9, Q99K81	Gene names	Vps72, Tcfl1, Yl1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

AIM1_HUMAN
NC score	0.021393 (rank : 2174)	θ value	0.365318 (rank : 1533)
Query Neighborhood Hits	2923	Target Neighborhood Hits	247	Shared Neighborhood Hits	107
SwissProt Accessions	Q9Y4K1, O00296, Q5VWJ2	Gene names	AIM1
Domain Architecture
Description	Absent in melanoma 1 protein.

NOP5_HUMAN
NC score	0.021385 (rank : 2175)	θ value	0.47712 (rank : 1620)
Query Neighborhood Hits	2923	Target Neighborhood Hits	84	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y2X3, Q6PK08, Q9P036, Q9UFN3	Gene names	NOP5
Domain Architecture
Description	Nucleolar protein NOP5 (Nucleolar protein 5) (NOP58).

SYUG_MOUSE
NC score	0.021321 (rank : 2176)	θ value	0.0330416 (rank : 1276)
Query Neighborhood Hits	2923	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z0F7	Gene names	Sncg, Persyn
Domain Architecture
Description	Gamma-synuclein (Persyn).

HPLN1_HUMAN
NC score	0.021266 (rank : 2177)	θ value	1.81305 (rank : 1940)
Query Neighborhood Hits	2923	Target Neighborhood Hits	67	Shared Neighborhood Hits	54
SwissProt Accessions	P10915	Gene names	HAPLN1, CRTL1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 1 precursor (Proteoglycan link protein) (Cartilage link protein) (LP).

AHTF1_HUMAN
NC score	0.021254 (rank : 2178)	θ value	5.27518 (rank : 2379)
Query Neighborhood Hits	2923	Target Neighborhood Hits	286	Shared Neighborhood Hits	129
SwissProt Accessions	Q8WYP5, Q7Z4E3, Q8IZA4, Q96EH9, Q9Y4Q6	Gene names	AHCTF1, ELYS, TMBS62
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

TTC16_HUMAN
NC score	0.021217 (rank : 2179)	θ value	0.62314 (rank : 1697)
Query Neighborhood Hits	2923	Target Neighborhood Hits	417	Shared Neighborhood Hits	142
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

CABYR_HUMAN
NC score	0.021208 (rank : 2180)	θ value	0.813845 (rank : 1708)
Query Neighborhood Hits	2923	Target Neighborhood Hits	87	Shared Neighborhood Hits	39
SwissProt Accessions	O75952, Q8WXW5, Q9HAY3, Q9HAY4, Q9HAY5, Q9HCY9	Gene names	CABYR, CBP86, FSP2
Domain Architecture	No domain graphic available
Description	Calcium-binding tyrosine phosphorylation-regulated protein (Calcium- binding protein 86) (Testis-specific calcium-binding protein CBP86) (Fibrousheathin-2) (FSP-2).

LTBP4_MOUSE
NC score	0.021171 (rank : 2181)	θ value	8.99809 (rank : 2827)
Query Neighborhood Hits	2923	Target Neighborhood Hits	607	Shared Neighborhood Hits	154
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

YETS2_HUMAN
NC score	0.021061 (rank : 2182)	θ value	5.27518 (rank : 2531)
Query Neighborhood Hits	2923	Target Neighborhood Hits	212	Shared Neighborhood Hits	92
SwissProt Accessions	Q9ULM3, Q641P6, Q9NW96	Gene names	YEATS2, KIAA1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

SCN3B_HUMAN
NC score	0.021045 (rank : 2183)	θ value	4.03905 (rank : 2352)
Query Neighborhood Hits	2923	Target Neighborhood Hits	85	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NY72, Q9ULR2	Gene names	SCN3B, KIAA1158
Domain Architecture
Description	Sodium channel beta-3 subunit precursor.

LAP4_MOUSE
NC score	0.021025 (rank : 2184)	θ value	3.0926 (rank : 2184)
Query Neighborhood Hits	2923	Target Neighborhood Hits	590	Shared Neighborhood Hits	157
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

HPLN3_HUMAN
NC score	0.020870 (rank : 2185)	θ value	2.36792 (rank : 2056)
Query Neighborhood Hits	2923	Target Neighborhood Hits	70	Shared Neighborhood Hits	54
SwissProt Accessions	Q96S86	Gene names	HAPLN3
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 3 precursor.

IF4B_HUMAN
NC score	0.020770 (rank : 2186)	θ value	4.03905 (rank : 2295)
Query Neighborhood Hits	2923	Target Neighborhood Hits	417	Shared Neighborhood Hits	122
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

KIF3B_MOUSE
NC score	0.020697 (rank : 2187)	θ value	1.38821 (rank : 1858)
Query Neighborhood Hits	2923	Target Neighborhood Hits	533	Shared Neighborhood Hits	249
SwissProt Accessions	Q61771	Gene names	Kif3b
Domain Architecture
Description	Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B).

SEM3C_HUMAN
NC score	0.020677 (rank : 2188)	θ value	0.0736092 (rank : 1352)
Query Neighborhood Hits	2923	Target Neighborhood Hits	106	Shared Neighborhood Hits	61
SwissProt Accessions	Q99985	Gene names	SEMA3C, SEMAE
Domain Architecture
Description	Semaphorin-3C precursor (Semaphorin E) (Sema E).

TTF2_MOUSE
NC score	0.020629 (rank : 2189)	θ value	0.125558 (rank : 1404)
Query Neighborhood Hits	2923	Target Neighborhood Hits	364	Shared Neighborhood Hits	161
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

RNF8_HUMAN
NC score	0.020614 (rank : 2190)	θ value	5.27518 (rank : 2500)
Query Neighborhood Hits	2923	Target Neighborhood Hits	622	Shared Neighborhood Hits	221
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

SVIL_HUMAN
NC score	0.020603 (rank : 2191)	θ value	0.47712 (rank : 1635)
Query Neighborhood Hits	2923	Target Neighborhood Hits	232	Shared Neighborhood Hits	104
SwissProt Accessions	O95425, O60611, O60612, Q5VZK5, Q5VZK6, Q9H1R7	Gene names	SVIL
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

MORC2_HUMAN
NC score	0.020598 (rank : 2192)	θ value	8.99809 (rank : 2833)
Query Neighborhood Hits	2923	Target Neighborhood Hits	207	Shared Neighborhood Hits	123
SwissProt Accessions	Q9Y6X9, Q9UF28, Q9Y6V2	Gene names	MORC2, KIAA0852, ZCWCC1
Domain Architecture
Description	MORC family CW-type zinc finger protein 2 (Zinc finger CW-type coiled- coil domain protein 1).

ANR38_MOUSE
NC score	0.020583 (rank : 2193)	θ value	2.36792 (rank : 2014)
Query Neighborhood Hits	2923	Target Neighborhood Hits	512	Shared Neighborhood Hits	194
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

KIF3B_HUMAN
NC score	0.020496 (rank : 2194)	θ value	1.06291 (rank : 1791)
Query Neighborhood Hits	2923	Target Neighborhood Hits	540	Shared Neighborhood Hits	256
SwissProt Accessions	O15066	Gene names	KIF3B, KIAA0359
Domain Architecture
Description	Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B) (HH0048).

SMRC2_MOUSE
NC score	0.020468 (rank : 2195)	θ value	4.03905 (rank : 2358)
Query Neighborhood Hits	2923	Target Neighborhood Hits	487	Shared Neighborhood Hits	193
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

ANTR1_MOUSE
NC score	0.020383 (rank : 2196)	θ value	3.0926 (rank : 2127)
Query Neighborhood Hits	2923	Target Neighborhood Hits	143	Shared Neighborhood Hits	89
SwissProt Accessions	Q9CZ52	Gene names	Antxr1, Atr, Tem8
Domain Architecture
Description	Anthrax toxin receptor 1 precursor (Tumor endothelial marker 8).

PHC2_HUMAN
NC score	0.020323 (rank : 2197)	θ value	0.21417 (rank : 1473)
Query Neighborhood Hits	2923	Target Neighborhood Hits	388	Shared Neighborhood Hits	166
SwissProt Accessions	Q8IXK0, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7	Gene names	PHC2, EDR2, PH2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2).

MOR2A_MOUSE
NC score	0.020239 (rank : 2198)	θ value	0.125558 (rank : 1393)
Query Neighborhood Hits	2923	Target Neighborhood Hits	220	Shared Neighborhood Hits	117
SwissProt Accessions	Q69ZX6, Q5QNQ7, Q6P547	Gene names	Morc2a, Kiaa0852, Zcwcc1
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 2A (Zinc finger CW-type coiled-coil domain protein 1).

SMRC1_HUMAN
NC score	0.020212 (rank : 2199)	θ value	8.99809 (rank : 2883)
Query Neighborhood Hits	2923	Target Neighborhood Hits	375	Shared Neighborhood Hits	196
SwissProt Accessions	Q92922, Q6P172, Q8IWH2	Gene names	SMARCC1, BAF155
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155).

COGA1_HUMAN
NC score	0.020173 (rank : 2200)	θ value	6.88961 (rank : 2574)
Query Neighborhood Hits	2923	Target Neighborhood Hits	345	Shared Neighborhood Hits	105
SwissProt Accessions	Q07092	Gene names	COL16A1
Domain Architecture
Description	Collagen alpha-1(XVI) chain precursor.

MAVS_MOUSE
NC score	0.020153 (rank : 2201)	θ value	5.27518 (rank : 2460)
Query Neighborhood Hits	2923	Target Neighborhood Hits	170	Shared Neighborhood Hits	74
SwissProt Accessions	Q8VCF0	Gene names	Mavs, Ips1, Visa
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif).

HPPD_MOUSE
NC score	0.020130 (rank : 2202)	θ value	0.0563607 (rank : 1311)
Query Neighborhood Hits	2923	Target Neighborhood Hits	6	Shared Neighborhood Hits	4
SwissProt Accessions	P49429, P97322, Q3UEQ0, Q91WV9	Gene names	Hpd
Domain Architecture
Description	4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) (4HPPD) (HPD) (4- hydroxyphenylpyruvic acid oxidase) (HPPDase) (F protein) (F Alloantigen).

H15_MOUSE
NC score	0.020079 (rank : 2203)	θ value	1.38821 (rank : 1848)
Query Neighborhood Hits	2923	Target Neighborhood Hits	79	Shared Neighborhood Hits	44
SwissProt Accessions	P43276, Q9CRM8	Gene names	Hist1h1b, H1f5
Domain Architecture
Description	Histone H1.5 (H1 VAR.5) (H1b).

CABYR_MOUSE
NC score	0.020061 (rank : 2204)	θ value	0.47712 (rank : 1590)
Query Neighborhood Hits	2923	Target Neighborhood Hits	80	Shared Neighborhood Hits	33
SwissProt Accessions	Q9D424, Q91Y41, Q91Y42	Gene names	Cabyr, Cbp86
Domain Architecture	No domain graphic available
Description	Calcium-binding tyrosine phosphorylation-regulated protein (Calcium- binding protein 86) (Testis-specific calcium-binding protein CBP86).

HPLN1_MOUSE
NC score	0.020034 (rank : 2205)	θ value	0.813845 (rank : 1728)
Query Neighborhood Hits	2923	Target Neighborhood Hits	64	Shared Neighborhood Hits	50
SwissProt Accessions	Q9QUP5, Q9D1G9, Q9Z1X7	Gene names	Hapln1, Crtl1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 1 precursor (Proteoglycan link protein) (Cartilage link protein) (LP).

IL2RG_HUMAN
NC score	0.019850 (rank : 2206)	θ value	0.0961366 (rank : 1367)
Query Neighborhood Hits	2923	Target Neighborhood Hits	34	Shared Neighborhood Hits	16
SwissProt Accessions	P31785	Gene names	IL2RG
Domain Architecture
Description	Cytokine receptor common gamma chain precursor (Gamma-C) (Interleukin- 2 receptor gamma chain) (IL-2R gamma chain) (p64) (CD132 antigen).

NRBF2_MOUSE
NC score	0.019771 (rank : 2207)	θ value	0.365318 (rank : 1561)
Query Neighborhood Hits	2923	Target Neighborhood Hits	113	Shared Neighborhood Hits	66
SwissProt Accessions	Q8VCQ3, Q9DCG3	Gene names	Nrbf2
Domain Architecture	No domain graphic available
Description	Nuclear receptor-binding factor 2 (NRBF-2).

REC8L_HUMAN
NC score	0.019767 (rank : 2208)	θ value	3.0926 (rank : 2217)
Query Neighborhood Hits	2923	Target Neighborhood Hits	45	Shared Neighborhood Hits	27
SwissProt Accessions	O95072, Q8WUV8, Q9BTF2, Q9NVQ9	Gene names	REC8L1, REC8
Domain Architecture
Description	Meiotic recombination protein REC8-like 1 (Cohesin Rec8p).

SMPX_HUMAN
NC score	0.019733 (rank : 2209)	θ value	0.365318 (rank : 1570)
Query Neighborhood Hits	2923	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UHP9	Gene names	SMPX, SRMX
Domain Architecture	No domain graphic available
Description	Small muscular protein (Stretch-responsive skeletal muscle protein).

CO6A3_HUMAN
NC score	0.019698 (rank : 2210)	θ value	0.47712 (rank : 1599)
Query Neighborhood Hits	2923	Target Neighborhood Hits	317	Shared Neighborhood Hits	99
SwissProt Accessions	P12111, Q16501	Gene names	COL6A3
Domain Architecture
Description	Collagen alpha-3(VI) chain precursor.

WDR76_HUMAN
NC score	0.019692 (rank : 2211)	θ value	0.0252991 (rank : 1260)
Query Neighborhood Hits	2923	Target Neighborhood Hits	73	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H967	Gene names	WDR76
Domain Architecture	No domain graphic available
Description	WD repeat protein 76.

MY116_MOUSE
NC score	0.019609 (rank : 2212)	θ value	1.81305 (rank : 1960)
Query Neighborhood Hits	2923	Target Neighborhood Hits	70	Shared Neighborhood Hits	32
SwissProt Accessions	P17564	Gene names	Myd116
Domain Architecture	No domain graphic available
Description	Myeloid differentiation primary response protein MyD116.

ESCO2_HUMAN
NC score	0.019595 (rank : 2213)	θ value	0.21417 (rank : 1458)
Query Neighborhood Hits	2923	Target Neighborhood Hits	45	Shared Neighborhood Hits	25
SwissProt Accessions	Q56NI9	Gene names	ESCO2
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO2 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 2) (ECO1 homolog 2).

SEM4D_MOUSE
NC score	0.019579 (rank : 2214)	θ value	0.365318 (rank : 1568)
Query Neighborhood Hits	2923	Target Neighborhood Hits	143	Shared Neighborhood Hits	65
SwissProt Accessions	O09126	Gene names	Sema4d, Semacl2, Semaj
Domain Architecture
Description	Semaphorin-4D precursor (Semaphorin J) (Sema J) (Semaphorin C-like 2) (M-Sema G).

CHMP6_MOUSE
NC score	0.019496 (rank : 2215)	θ value	0.47712 (rank : 1596)
Query Neighborhood Hits	2923	Target Neighborhood Hits	99	Shared Neighborhood Hits	42
SwissProt Accessions	P0C0A3	Gene names	Chmp6
Domain Architecture	No domain graphic available
Description	Charged multivesicular body protein 6 (Chromatin-modifying protein 6).

SEM4C_HUMAN
NC score	0.019423 (rank : 2216)	θ value	0.0431538 (rank : 1295)
Query Neighborhood Hits	2923	Target Neighborhood Hits	84	Shared Neighborhood Hits	35
SwissProt Accessions	Q9C0C4, Q7Z5X0	Gene names	SEMA4C, KIAA1739
Domain Architecture
Description	Semaphorin-4C precursor.

HPPD_HUMAN
NC score	0.019335 (rank : 2217)	θ value	0.0961366 (rank : 1364)
Query Neighborhood Hits	2923	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	P32754, Q13234	Gene names	HPD, PPD
Domain Architecture
Description	4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) (4HPPD) (HPD) (HPPDase) (4-hydroxyphenylpyruvic acid oxidase).

DNJC8_MOUSE
NC score	0.019299 (rank : 2218)	θ value	5.27518 (rank : 2411)
Query Neighborhood Hits	2923	Target Neighborhood Hits	392	Shared Neighborhood Hits	182
SwissProt Accessions	Q6NZB0, Q6PG72, Q8C2M6	Gene names	Dnajc8
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 8.

PHF14_HUMAN
NC score	0.019026 (rank : 2219)	θ value	5.27518 (rank : 2492)
Query Neighborhood Hits	2923	Target Neighborhood Hits	447	Shared Neighborhood Hits	210
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

BRD8_HUMAN
NC score	0.019016 (rank : 2220)	θ value	0.0330416 (rank : 1263)
Query Neighborhood Hits	2923	Target Neighborhood Hits	292	Shared Neighborhood Hits	104
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

CASL_MOUSE
NC score	0.019006 (rank : 2221)	θ value	0.365318 (rank : 1537)
Query Neighborhood Hits	2923	Target Neighborhood Hits	225	Shared Neighborhood Hits	70
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

E41L2_MOUSE
NC score	0.019002 (rank : 2222)	θ value	1.38821 (rank : 1841)
Query Neighborhood Hits	2923	Target Neighborhood Hits	459	Shared Neighborhood Hits	213
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

IZUM1_MOUSE
NC score	0.018694 (rank : 2223)	θ value	1.38821 (rank : 1853)
Query Neighborhood Hits	2923	Target Neighborhood Hits	41	Shared Neighborhood Hits	18
SwissProt Accessions	Q9D9J7	Gene names	Izumo1
Domain Architecture	No domain graphic available
Description	Izumo sperm-egg fusion protein 1 precursor (Sperm-specific protein izumo).

RT35_HUMAN
NC score	0.018682 (rank : 2224)	θ value	0.365318 (rank : 1567)
Query Neighborhood Hits	2923	Target Neighborhood Hits	73	Shared Neighborhood Hits	39
SwissProt Accessions	P82673, Q32LZ1, Q6P4C6, Q7L1M6, Q96AI0, Q9H044, Q9HC14, Q9P1R5	Gene names	MRPS35, MRPS28
Domain Architecture	No domain graphic available
Description	28S ribosomal protein S35, mitochondrial precursor (S35mt) (MRP-S35) (Mitochondrial ribosomal protein S28) (MRP-S28).

SYTL2_MOUSE
NC score	0.018649 (rank : 2225)	θ value	1.38821 (rank : 1893)
Query Neighborhood Hits	2923	Target Neighborhood Hits	253	Shared Neighborhood Hits	72
SwissProt Accessions	Q99N50, Q8BT37, Q99J89, Q99J90, Q99N51, Q99N52, Q99N55, Q99N56	Gene names	Sytl2, Slp2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

CF150_HUMAN
NC score	0.018487 (rank : 2226)	θ value	8.99809 (rank : 2750)
Query Neighborhood Hits	2923	Target Neighborhood Hits	96	Shared Neighborhood Hits	46
SwissProt Accessions	Q8N884, Q32NC9, Q5SWL0, Q5SWL1, Q96E45	Gene names	C6orf150
Domain Architecture	No domain graphic available
Description	Protein C6orf150.

HS105_HUMAN
NC score	0.018487 (rank : 2227)	θ value	0.0148317 (rank : 1218)
Query Neighborhood Hits	2923	Target Neighborhood Hits	209	Shared Neighborhood Hits	115
SwissProt Accessions	Q92598, O95739, Q5TBM6, Q5TBM8, Q9UPC4	Gene names	HSPH1, HSP105, HSP110, KIAA0201
Domain Architecture
Description	Heat-shock protein 105 kDa (Heat shock 110 kDa protein) (Antigen NY- CO-25).

ANTR1_HUMAN
NC score	0.018394 (rank : 2228)	θ value	4.03905 (rank : 2249)
Query Neighborhood Hits	2923	Target Neighborhood Hits	128	Shared Neighborhood Hits	78
SwissProt Accessions	Q9H6X2, Q96P02, Q9NVP3	Gene names	ANTXR1, ATR, TEM8
Domain Architecture
Description	Anthrax toxin receptor 1 precursor (Tumor endothelial marker 8).

MED6_HUMAN
NC score	0.018389 (rank : 2229)	θ value	0.47712 (rank : 1614)
Query Neighborhood Hits	2923	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	O75586, O15401, Q9BTH1, Q9UHL1	Gene names	MED6, ARC33
Domain Architecture
Description	RNA polymerase transcriptional regulation mediator, subunit 6 homolog (Activator-recruited cofactor 33 kDa component) (ARC33) (NY-REN-28 antigen).

PHF14_MOUSE
NC score	0.018293 (rank : 2230)	θ value	1.38821 (rank : 1870)
Query Neighborhood Hits	2923	Target Neighborhood Hits	342	Shared Neighborhood Hits	167
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

SCG2_HUMAN
NC score	0.018286 (rank : 2231)	θ value	5.27518 (rank : 2505)
Query Neighborhood Hits	2923	Target Neighborhood Hits	190	Shared Neighborhood Hits	94
SwissProt Accessions	P13521, Q8TBH3	Gene names	SCG2, CHGC
Domain Architecture
Description	Secretogranin-2 precursor (Secretogranin II) (SgII) (Chromogranin C) [Contains: Secretoneurin (SN)].

PACS1_HUMAN
NC score	0.018212 (rank : 2232)	θ value	0.813845 (rank : 1738)
Query Neighborhood Hits	2923	Target Neighborhood Hits	82	Shared Neighborhood Hits	46
SwissProt Accessions	Q6VY07, Q6PJY6, Q6PKB6, Q7Z590, Q7Z5W4, Q8N8K6, Q96MW0, Q9NW92, Q9ULP5	Gene names	PACS1, KIAA1175
Domain Architecture	No domain graphic available
Description	Phosphofurin acidic cluster sorting protein 1 (PACS-1).

RPTN_MOUSE
NC score	0.018198 (rank : 2233)	θ value	1.81305 (rank : 1977)
Query Neighborhood Hits	2923	Target Neighborhood Hits	650	Shared Neighborhood Hits	209
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

KI21B_HUMAN
NC score	0.018124 (rank : 2234)	θ value	8.99809 (rank : 2810)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1017	Shared Neighborhood Hits	346
SwissProt Accessions	O75037, Q5T4J3	Gene names	KIF21B, KIAA0449
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B.

HS74L_HUMAN
NC score	0.018108 (rank : 2235)	θ value	0.0252991 (rank : 1252)
Query Neighborhood Hits	2923	Target Neighborhood Hits	141	Shared Neighborhood Hits	82
SwissProt Accessions	O95757, Q4W5M5, Q8IWA2	Gene names	HSPA4L, APG1, OSP94
Domain Architecture
Description	Heat shock 70 kDa protein 4L (Osmotic stress protein 94) (Heat shock 70-related protein APG-1).

RFC1_MOUSE
NC score	0.018061 (rank : 2236)	θ value	4.03905 (rank : 2342)
Query Neighborhood Hits	2923	Target Neighborhood Hits	290	Shared Neighborhood Hits	127
SwissProt Accessions	P35601	Gene names	Rfc1, Ibf-1, Recc1
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (A1-P145) (Differentiation- specific element-binding protein) (ISRE-binding protein).

RN168_MOUSE
NC score	0.018021 (rank : 2237)	θ value	2.36792 (rank : 2098)
Query Neighborhood Hits	2923	Target Neighborhood Hits	440	Shared Neighborhood Hits	153
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

H13_HUMAN
NC score	0.017891 (rank : 2238)	θ value	0.62314 (rank : 1670)
Query Neighborhood Hits	2923	Target Neighborhood Hits	61	Shared Neighborhood Hits	31
SwissProt Accessions	P16402	Gene names	HIST1H1D, H1F3
Domain Architecture
Description	Histone H1.3 (Histone H1c).

GBP5_HUMAN
NC score	0.017888 (rank : 2239)	θ value	4.03905 (rank : 2282)
Query Neighborhood Hits	2923	Target Neighborhood Hits	200	Shared Neighborhood Hits	112
SwissProt Accessions	Q96PP8	Gene names	GBP5
Domain Architecture
Description	Interferon-induced guanylate-binding protein 5 (GTP-binding protein 5) (Guanine nucleotide-binding protein 5) (GBP-5) (GBP-TA antigen).

CN092_MOUSE
NC score	0.017869 (rank : 2240)	θ value	0.279714 (rank : 1490)
Query Neighborhood Hits	2923	Target Neighborhood Hits	206	Shared Neighborhood Hits	88
SwissProt Accessions	Q8BU11, Q80UI2, Q99PN9, Q9CS16	Gene names
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

IGHDM_MOUSE
NC score	0.017814 (rank : 2241)	θ value	1.06291 (rank : 1788)
Query Neighborhood Hits	2923	Target Neighborhood Hits	162	Shared Neighborhood Hits	46
SwissProt Accessions	P01882	Gene names
Domain Architecture	No domain graphic available
Description	Ig delta chain C region membrane-bound form.

ASPH_HUMAN
NC score	0.017793 (rank : 2242)	θ value	2.36792 (rank : 2015)
Query Neighborhood Hits	2923	Target Neighborhood Hits	158	Shared Neighborhood Hits	57
SwissProt Accessions	Q12797	Gene names	ASPH
Domain Architecture
Description	Aspartyl/asparaginyl beta-hydroxylase (EC 1.14.11.16) (Aspartate beta- hydroxylase) (ASP beta-hydroxylase) (Peptide-aspartate beta- dioxygenase).

CSPG3_HUMAN
NC score	0.017754 (rank : 2243)	θ value	3.0926 (rank : 2150)
Query Neighborhood Hits	2923	Target Neighborhood Hits	676	Shared Neighborhood Hits	180
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

C8AP2_MOUSE
NC score	0.017747 (rank : 2244)	θ value	8.99809 (rank : 2741)
Query Neighborhood Hits	2923	Target Neighborhood Hits	405	Shared Neighborhood Hits	175
SwissProt Accessions	Q9WUF3, Q9CSW2	Gene names	Casp8ap2, Flash
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

CC47_MOUSE
NC score	0.017683 (rank : 2245)	θ value	0.21417 (rank : 1444)
Query Neighborhood Hits	2923	Target Neighborhood Hits	245	Shared Neighborhood Hits	81
SwissProt Accessions	Q9D024, Q3TSB5, Q3V1S7, Q8C5D9, Q920S6	Gene names	Ccdc47, Asp4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor (Adipocyte-specific protein 4).

OS9_HUMAN
NC score	0.017683 (rank : 2246)	θ value	2.36792 (rank : 2088)
Query Neighborhood Hits	2923	Target Neighborhood Hits	134	Shared Neighborhood Hits	66
SwissProt Accessions	Q13438, O00579	Gene names	OS9
Domain Architecture	No domain graphic available
Description	Protein OS-9 precursor (Amplified in osteosarcoma 9).

ARID2_HUMAN
NC score	0.017677 (rank : 2247)	θ value	1.81305 (rank : 1911)
Query Neighborhood Hits	2923	Target Neighborhood Hits	302	Shared Neighborhood Hits	102
SwissProt Accessions	Q68CP9, Q5EB51, Q645I3, Q6ZRY5, Q7Z3I5, Q86T28, Q96SJ6, Q9HCL5	Gene names	ARID2, KIAA1557
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 2 (ARID domain- containing protein 2) (BRG1-associated factor 200) (BAF200).

NOC3L_MOUSE
NC score	0.017603 (rank : 2248)	θ value	4.03905 (rank : 2327)
Query Neighborhood Hits	2923	Target Neighborhood Hits	177	Shared Neighborhood Hits	93
SwissProt Accessions	Q8VI84, Q9JKM3	Gene names	Noc3l, Ad24, Fad24
Domain Architecture	No domain graphic available
Description	Nucleolar complex protein 3 homolog (NOC3 protein homolog) (NOC3-like protein) (Nucleolar complex-associated protein 3-like protein) (Factor for adipocyte differentiation 24).

DNJC8_HUMAN
NC score	0.017585 (rank : 2249)	θ value	5.27518 (rank : 2410)
Query Neighborhood Hits	2923	Target Neighborhood Hits	380	Shared Neighborhood Hits	173
SwissProt Accessions	O75937, Q6IBA4, Q8N4Z5, Q9P051, Q9P067	Gene names	DNAJC8, SPF31
Domain Architecture
Description	DnaJ homolog subfamily C member 8 (Splicing protein spf31).

LTB1L_HUMAN
NC score	0.017575 (rank : 2250)	θ value	6.88961 (rank : 2643)
Query Neighborhood Hits	2923	Target Neighborhood Hits	553	Shared Neighborhood Hits	124
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

PWWP2_HUMAN
NC score	0.017444 (rank : 2251)	θ value	1.06291 (rank : 1805)
Query Neighborhood Hits	2923	Target Neighborhood Hits	80	Shared Neighborhood Hits	33
SwissProt Accessions	Q6NUJ5, Q5SZI0, Q6ZQX5, Q96F43	Gene names	PWWP2
Domain Architecture	No domain graphic available
Description	PWWP domain-containing protein 2.

GPVI_HUMAN
NC score	0.017398 (rank : 2252)	θ value	2.36792 (rank : 2052)
Query Neighborhood Hits	2923	Target Neighborhood Hits	68	Shared Neighborhood Hits	45
SwissProt Accessions	Q9HCN6, Q9HCN7, Q9UIF2	Gene names	GP6, GPVI
Domain Architecture	No domain graphic available
Description	Platelet glycoprotein VI precursor.

S23IP_MOUSE
NC score	0.017309 (rank : 2253)	θ value	3.0926 (rank : 2219)
Query Neighborhood Hits	2923	Target Neighborhood Hits	363	Shared Neighborhood Hits	140
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

BAIP3_HUMAN
NC score	0.017307 (rank : 2254)	θ value	4.03905 (rank : 2255)
Query Neighborhood Hits	2923	Target Neighborhood Hits	108	Shared Neighborhood Hits	22
SwissProt Accessions	O94812, O94839, Q2M226, Q658J2, Q76N05, Q96RZ3, Q9UJK1	Gene names	BAIAP3, KIAA0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

DAG1_HUMAN
NC score	0.017260 (rank : 2255)	θ value	8.99809 (rank : 2763)
Query Neighborhood Hits	2923	Target Neighborhood Hits	104	Shared Neighborhood Hits	64
SwissProt Accessions	Q14118	Gene names	DAG1
Domain Architecture
Description	Dystroglycan precursor (Dystrophin-associated glycoprotein 1) [Contains: Alpha-dystroglycan (Alpha-DG); Beta-dystroglycan (Beta- DG)].

RFIP1_MOUSE
NC score	0.017256 (rank : 2256)	θ value	0.813845 (rank : 1745)
Query Neighborhood Hits	2923	Target Neighborhood Hits	152	Shared Neighborhood Hits	57
SwissProt Accessions	Q9D620, Q3UBC2, Q8BN24	Gene names	Rab11fip1, Rcp
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

DIAP2_HUMAN
NC score	0.017254 (rank : 2257)	θ value	2.36792 (rank : 2041)
Query Neighborhood Hits	2923	Target Neighborhood Hits	342	Shared Neighborhood Hits	176
SwissProt Accessions	O60879, O60878, Q8WX06, Q8WX48, Q9UJL2	Gene names	DIAPH2, DIA
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2).

LTB1S_HUMAN
NC score	0.017212 (rank : 2258)	θ value	6.88961 (rank : 2644)
Query Neighborhood Hits	2923	Target Neighborhood Hits	502	Shared Neighborhood Hits	106
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

CSPG2_MOUSE
NC score	0.017198 (rank : 2259)	θ value	1.06291 (rank : 1773)
Query Neighborhood Hits	2923	Target Neighborhood Hits	711	Shared Neighborhood Hits	189
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

FBN1_MOUSE
NC score	0.017068 (rank : 2260)	θ value	1.81305 (rank : 1935)
Query Neighborhood Hits	2923	Target Neighborhood Hits	563	Shared Neighborhood Hits	108
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

CN037_HUMAN
NC score	0.017061 (rank : 2261)	θ value	6.88961 (rank : 2569)
Query Neighborhood Hits	2923	Target Neighborhood Hits	118	Shared Neighborhood Hits	51
SwissProt Accessions	Q86TY3, Q6P5Q1, Q86TY1	Gene names	C14orf37
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 precursor.

CXXC6_HUMAN
NC score	0.017022 (rank : 2262)	θ value	2.36792 (rank : 2037)
Query Neighborhood Hits	2923	Target Neighborhood Hits	180	Shared Neighborhood Hits	71
SwissProt Accessions	Q8NFU7, Q5VUP7, Q7Z6B6, Q8TCR1, Q9C0I7	Gene names	CXXC6, KIAA1676, LCX
Domain Architecture	No domain graphic available
Description	CXXC-type zinc finger protein 6 (Leukemia-associated protein with a CXXC domain).

ANK3_HUMAN
NC score	0.017009 (rank : 2263)	θ value	0.000270298 (rank : 1037)
Query Neighborhood Hits	2923	Target Neighborhood Hits	853	Shared Neighborhood Hits	278
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

SEM3F_HUMAN
NC score	0.016952 (rank : 2264)	θ value	1.38821 (rank : 1882)
Query Neighborhood Hits	2923	Target Neighborhood Hits	100	Shared Neighborhood Hits	54
SwissProt Accessions	Q13275, Q13274, Q13372, Q15704	Gene names	SEMA3F
Domain Architecture
Description	Semaphorin-3F precursor (Semaphorin IV) (Sema IV) (Sema III/F).

OXRP_HUMAN
NC score	0.016942 (rank : 2265)	θ value	6.88961 (rank : 2664)
Query Neighborhood Hits	2923	Target Neighborhood Hits	544	Shared Neighborhood Hits	216
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

H15_HUMAN
NC score	0.016919 (rank : 2266)	θ value	4.03905 (rank : 2287)
Query Neighborhood Hits	2923	Target Neighborhood Hits	76	Shared Neighborhood Hits	35
SwissProt Accessions	P16401, Q14529	Gene names	HIST1H1B, H1F5
Domain Architecture
Description	Histone H1.5 (Histone H1a).

WBP4_MOUSE
NC score	0.016824 (rank : 2267)	θ value	0.279714 (rank : 1528)
Query Neighborhood Hits	2923	Target Neighborhood Hits	100	Shared Neighborhood Hits	36
SwissProt Accessions	Q61048, Q8K1Z9, Q9CS45	Gene names	Wbp4, Fbp21, Fnbp21
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 4 (WBP-4) (Formin-binding protein 21).

STAT2_MOUSE
NC score	0.016816 (rank : 2268)	θ value	0.00228821 (rank : 1122)
Query Neighborhood Hits	2923	Target Neighborhood Hits	175	Shared Neighborhood Hits	66
SwissProt Accessions	Q9WVL2, Q64188, Q64189, Q64250	Gene names	Stat2
Domain Architecture
Description	Signal transducer and activator of transcription 2.

DAB2P_HUMAN
NC score	0.016809 (rank : 2269)	θ value	1.38821 (rank : 1835)
Query Neighborhood Hits	2923	Target Neighborhood Hits	303	Shared Neighborhood Hits	145
SwissProt Accessions	Q5VWQ8, Q8TDL2, Q96SE1, Q9C0C0	Gene names	DAB2IP, AF9Q34, AIP1, KIAA1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein) (DAB2 interaction protein) (ASK-interacting protein 1).

CCD60_HUMAN
NC score	0.016780 (rank : 2270)	θ value	0.47712 (rank : 1592)
Query Neighborhood Hits	2923	Target Neighborhood Hits	21	Shared Neighborhood Hits	13
SwissProt Accessions	Q8IWA6	Gene names	CCDC60
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 60.

LPP_HUMAN
NC score	0.016668 (rank : 2271)	θ value	0.813845 (rank : 1732)
Query Neighborhood Hits	2923	Target Neighborhood Hits	775	Shared Neighborhood Hits	231
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

FXL19_MOUSE
NC score	0.016660 (rank : 2272)	θ value	0.0563607 (rank : 1308)
Query Neighborhood Hits	2923	Target Neighborhood Hits	217	Shared Neighborhood Hits	74
SwissProt Accessions	Q6PB97, Q7TSH0, Q8BIB4	Gene names	Fbxl19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

SEM4G_MOUSE
NC score	0.016648 (rank : 2273)	θ value	1.81305 (rank : 1983)
Query Neighborhood Hits	2923	Target Neighborhood Hits	99	Shared Neighborhood Hits	49
SwissProt Accessions	Q9WUH7	Gene names	Sema4g
Domain Architecture
Description	Semaphorin-4G precursor.

GNAS1_MOUSE
NC score	0.016630 (rank : 2274)	θ value	0.0193708 (rank : 1235)
Query Neighborhood Hits	2923	Target Neighborhood Hits	651	Shared Neighborhood Hits	201
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

KIF17_MOUSE
NC score	0.016622 (rank : 2275)	θ value	0.62314 (rank : 1674)
Query Neighborhood Hits	2923	Target Neighborhood Hits	452	Shared Neighborhood Hits	235
SwissProt Accessions	Q99PW8	Gene names	Kif17
Domain Architecture
Description	Kinesin-like protein KIF17 (MmKIF17).

PHLPL_HUMAN
NC score	0.016583 (rank : 2276)	θ value	5.27518 (rank : 2493)
Query Neighborhood Hits	2923	Target Neighborhood Hits	310	Shared Neighborhood Hits	65
SwissProt Accessions	Q6ZVD8, Q9NV17, Q9Y2E3	Gene names	PHLPPL, KIAA0931
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat protein phosphatase-like (EC 3.1.3.16).

COIA1_MOUSE
NC score	0.016527 (rank : 2277)	θ value	2.36792 (rank : 2035)
Query Neighborhood Hits	2923	Target Neighborhood Hits	481	Shared Neighborhood Hits	143
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

ANLN_HUMAN
NC score	0.016461 (rank : 2278)	θ value	5.27518 (rank : 2384)
Query Neighborhood Hits	2923	Target Neighborhood Hits	222	Shared Neighborhood Hits	103
SwissProt Accessions	Q9NQW6, Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0	Gene names	ANLN
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

IGHD_MOUSE
NC score	0.016455 (rank : 2279)	θ value	1.06291 (rank : 1789)
Query Neighborhood Hits	2923	Target Neighborhood Hits	160	Shared Neighborhood Hits	46
SwissProt Accessions	P01881	Gene names
Domain Architecture	No domain graphic available
Description	Ig delta chain C region secreted form.

ESCO1_MOUSE
NC score	0.016432 (rank : 2280)	θ value	3.0926 (rank : 2165)
Query Neighborhood Hits	2923	Target Neighborhood Hits	87	Shared Neighborhood Hits	54
SwissProt Accessions	Q69Z69, Q8BQI2, Q8BR47, Q922F5	Gene names	Esco1, Kiaa1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1).

SEM4G_HUMAN
NC score	0.016375 (rank : 2281)	θ value	0.62314 (rank : 1690)
Query Neighborhood Hits	2923	Target Neighborhood Hits	88	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NTN9, Q9HCF3	Gene names	SEMA4G, KIAA1619
Domain Architecture
Description	Semaphorin-4G precursor.

IF4G3_HUMAN
NC score	0.016367 (rank : 2282)	θ value	5.27518 (rank : 2443)
Query Neighborhood Hits	2923	Target Neighborhood Hits	247	Shared Neighborhood Hits	119
SwissProt Accessions	O43432, Q15597, Q8NEN1	Gene names	EIF4G3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

DZIP3_HUMAN
NC score	0.016324 (rank : 2283)	θ value	3.0926 (rank : 2159)
Query Neighborhood Hits	2923	Target Neighborhood Hits	399	Shared Neighborhood Hits	159
SwissProt Accessions	Q86Y13, O75162, Q6P3R9, Q6PH82, Q86Y14, Q86Y15, Q86Y16, Q8IWI0, Q96RS9	Gene names	DZIP3, KIAA0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3) (RNA-binding ubiquitin ligase of 138 kDa) (hRUL138).

MRE11_HUMAN
NC score	0.016316 (rank : 2284)	θ value	0.163984 (rank : 1427)
Query Neighborhood Hits	2923	Target Neighborhood Hits	95	Shared Neighborhood Hits	47
SwissProt Accessions	P49959, O43475	Gene names	MRE11A, HNGS1, MRE11
Domain Architecture
Description	Double-strand break repair protein MRE11A (MRE11 homolog 1) (MRE11 meiotic recombination 11 homolog A).

LTB1L_MOUSE
NC score	0.016187 (rank : 2285)	θ value	4.03905 (rank : 2309)
Query Neighborhood Hits	2923	Target Neighborhood Hits	514	Shared Neighborhood Hits	100
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

HS74L_MOUSE
NC score	0.016175 (rank : 2286)	θ value	0.0193708 (rank : 1236)
Query Neighborhood Hits	2923	Target Neighborhood Hits	141	Shared Neighborhood Hits	68
SwissProt Accessions	P48722, P97854, Q8BQD0, Q8CC45, Q91X29	Gene names	Hspa4l, Apg1, Hsp4l, Osp94
Domain Architecture
Description	Heat shock 70 kDa protein 4L (Osmotic stress protein 94) (Heat shock 70-related protein APG-1).

AHTF1_MOUSE
NC score	0.016170 (rank : 2287)	θ value	8.99809 (rank : 2724)
Query Neighborhood Hits	2923	Target Neighborhood Hits	176	Shared Neighborhood Hits	77
SwissProt Accessions	Q8CJF7, Q8BVJ5, Q8VD55	Gene names	Ahctf1, Elys
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

LTB1S_MOUSE
NC score	0.016108 (rank : 2288)	θ value	4.03905 (rank : 2310)
Query Neighborhood Hits	2923	Target Neighborhood Hits	479	Shared Neighborhood Hits	92
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

DAB2P_MOUSE
NC score	0.016101 (rank : 2289)	θ value	1.38821 (rank : 1836)
Query Neighborhood Hits	2923	Target Neighborhood Hits	284	Shared Neighborhood Hits	138
SwissProt Accessions	Q3UHC7, Q3TPD5, Q3UH44, Q6JTV1, Q80T97	Gene names	Dab2ip, Kiaa1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein).

TAB3_MOUSE
NC score	0.015936 (rank : 2290)	θ value	1.81305 (rank : 1991)
Query Neighborhood Hits	2923	Target Neighborhood Hits	273	Shared Neighborhood Hits	108
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

HM20A_MOUSE
NC score	0.015890 (rank : 2291)	θ value	1.38821 (rank : 1850)
Query Neighborhood Hits	2923	Target Neighborhood Hits	348	Shared Neighborhood Hits	154
SwissProt Accessions	Q9DC33, Q3LSF9, Q6NV87, Q8BSK1, Q8C3C1, Q8CAA0, Q9CYG2	Gene names	Hmg20a, Ibraf
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (iBRAF) (Inhibitor of BRAF35) (HMG domain protein HMGX1).

CSPG2_HUMAN
NC score	0.015801 (rank : 2292)	θ value	6.88961 (rank : 2576)
Query Neighborhood Hits	2923	Target Neighborhood Hits	681	Shared Neighborhood Hits	175
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

ARMX4_HUMAN
NC score	0.015725 (rank : 2293)	θ value	1.81305 (rank : 1912)
Query Neighborhood Hits	2923	Target Neighborhood Hits	60	Shared Neighborhood Hits	31
SwissProt Accessions	Q5H9R4, Q5H9K8, Q8N8D6	Gene names	ARMCX4
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 4.

CO4A5_HUMAN
NC score	0.015722 (rank : 2294)	θ value	1.06291 (rank : 1771)
Query Neighborhood Hits	2923	Target Neighborhood Hits	383	Shared Neighborhood Hits	120
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

KI13A_MOUSE
NC score	0.015676 (rank : 2295)	θ value	0.0252991 (rank : 1255)
Query Neighborhood Hits	2923	Target Neighborhood Hits	395	Shared Neighborhood Hits	202
SwissProt Accessions	Q9EQW7, O35062	Gene names	Kif13a
Domain Architecture
Description	Kinesin-like protein KIF13A.

MICA1_MOUSE
NC score	0.015661 (rank : 2296)	θ value	5.27518 (rank : 2465)
Query Neighborhood Hits	2923	Target Neighborhood Hits	400	Shared Neighborhood Hits	187
SwissProt Accessions	Q8VDP3	Gene names	Mical1, Mical, Nical
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

INGR2_HUMAN
NC score	0.015645 (rank : 2297)	θ value	3.0926 (rank : 2176)
Query Neighborhood Hits	2923	Target Neighborhood Hits	22	Shared Neighborhood Hits	13
SwissProt Accessions	P38484, Q9BTL5	Gene names	IFNGR2, IFNGT1
Domain Architecture
Description	Interferon-gamma receptor beta chain precursor (Interferon-gamma receptor accessory factor 1) (AF-1) (Interferon-gamma transducer 1).

PHF2_MOUSE
NC score	0.015640 (rank : 2298)	θ value	4.03905 (rank : 2331)
Query Neighborhood Hits	2923	Target Neighborhood Hits	241	Shared Neighborhood Hits	103
SwissProt Accessions	Q9WTU0, Q80WA8	Gene names	Phf2
Domain Architecture
Description	PHD finger protein 2 (GRC5).

DESM_HUMAN
NC score	0.015636 (rank : 2299)	θ value	5.27518 (rank : 2407)
Query Neighborhood Hits	2923	Target Neighborhood Hits	495	Shared Neighborhood Hits	222
SwissProt Accessions	P17661, Q15787, Q8IZR1, Q8IZR6, Q8NES2, Q8NEU6, Q8TAC4, Q8TCX2, Q8TD99, Q9UHN5, Q9UJ80	Gene names	DES
Domain Architecture
Description	Desmin.

CO1A1_MOUSE
NC score	0.015605 (rank : 2300)	θ value	6.88961 (rank : 2572)
Query Neighborhood Hits	2923	Target Neighborhood Hits	457	Shared Neighborhood Hits	142
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

SLC2B_HUMAN
NC score	0.015580 (rank : 2301)	θ value	8.99809 (rank : 2880)
Query Neighborhood Hits	2923	Target Neighborhood Hits	214	Shared Neighborhood Hits	82
SwissProt Accessions	Q8NEV8, Q9Y4D6	Gene names	EXPH5, KIAA0624, SLAC2B
Domain Architecture	No domain graphic available
Description	Slp homolog lacking C2 domains b (Exophilin-5).

BAIP3_MOUSE
NC score	0.015541 (rank : 2302)	θ value	3.0926 (rank : 2129)
Query Neighborhood Hits	2923	Target Neighborhood Hits	112	Shared Neighborhood Hits	21
SwissProt Accessions	Q80TT2, Q6RUT4	Gene names	Baiap3, Gm937, Kiaa0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

UN84B_HUMAN
NC score	0.015512 (rank : 2303)	θ value	0.279714 (rank : 1526)
Query Neighborhood Hits	2923	Target Neighborhood Hits	172	Shared Neighborhood Hits	96
SwissProt Accessions	Q9UH99, O75156, Q6B4H1, Q7Z3E3	Gene names	UNC84B, FRIGG, KIAA0668, RAB5IP, SUN2
Domain Architecture	No domain graphic available
Description	Sad1/unc-84-like protein 2 (Rab5-interacting protein) (Rab5IP).

LIRB4_MOUSE
NC score	0.015455 (rank : 2304)	θ value	0.21417 (rank : 1471)
Query Neighborhood Hits	2923	Target Neighborhood Hits	56	Shared Neighborhood Hits	32
SwissProt Accessions	Q64281, Q64312	Gene names	Lilrb4, Gp49b
Domain Architecture	No domain graphic available
Description	Leukocyte immunoglobulin-like receptor subfamily B member 4 precursor (Mast cell surface glycoprotein Gp49B).

BCOR_HUMAN
NC score	0.015447 (rank : 2305)	θ value	0.0193708 (rank : 1227)
Query Neighborhood Hits	2923	Target Neighborhood Hits	609	Shared Neighborhood Hits	171
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

UBF1_HUMAN
NC score	0.015431 (rank : 2306)	θ value	2.36792 (rank : 2116)
Query Neighborhood Hits	2923	Target Neighborhood Hits	415	Shared Neighborhood Hits	159
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

HSP74_MOUSE
NC score	0.015424 (rank : 2307)	θ value	4.03905 (rank : 2291)
Query Neighborhood Hits	2923	Target Neighborhood Hits	257	Shared Neighborhood Hits	134
SwissProt Accessions	Q61316	Gene names	Hspa4, Hsp110
Domain Architecture
Description	Heat shock 70 kDa protein 4 (Heat shock 70-related protein APG-2).

SYAP1_MOUSE
NC score	0.015389 (rank : 2308)	θ value	1.06291 (rank : 1814)
Query Neighborhood Hits	2923	Target Neighborhood Hits	55	Shared Neighborhood Hits	32
SwissProt Accessions	Q9D5V6, Q3UI67, Q9D870	Gene names	Syap1
Domain Architecture
Description	Synapse-associated protein 1.

KIF17_HUMAN
NC score	0.015350 (rank : 2309)	θ value	0.0193708 (rank : 1238)
Query Neighborhood Hits	2923	Target Neighborhood Hits	365	Shared Neighborhood Hits	196
SwissProt Accessions	Q9P2E2, O95077, Q53YS6, Q5VWA9, Q6GSA8, Q8N411	Gene names	KIF17, KIAA1405, KIF3X
Domain Architecture
Description	Kinesin-like protein KIF17 (KIF3-related motor protein).

KI13B_HUMAN
NC score	0.015306 (rank : 2310)	θ value	8.99809 (rank : 2809)
Query Neighborhood Hits	2923	Target Neighborhood Hits	492	Shared Neighborhood Hits	252
SwissProt Accessions	Q9NQT8, O75134, Q9BYJ6	Gene names	KIF13B, GAKIN, KIAA0639
Domain Architecture
Description	Kinesin-like protein KIF13B (Kinesin-like protein GAKIN).

COFA1_HUMAN
NC score	0.015288 (rank : 2311)	θ value	8.99809 (rank : 2756)
Query Neighborhood Hits	2923	Target Neighborhood Hits	292	Shared Neighborhood Hits	100
SwissProt Accessions	P39059, Q5T6J4, Q9Y4W4	Gene names	COL15A1
Domain Architecture
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV) (Restin) (Related to endostatin)].

LRC50_HUMAN
NC score	0.015274 (rank : 2312)	θ value	5.27518 (rank : 2454)
Query Neighborhood Hits	2923	Target Neighborhood Hits	275	Shared Neighborhood Hits	76
SwissProt Accessions	Q8NEP3, Q69YI8, Q69YJ0, Q96LP3	Gene names	LRRC50
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 50.

MAGC1_HUMAN
NC score	0.015263 (rank : 2313)	θ value	1.06291 (rank : 1793)
Query Neighborhood Hits	2923	Target Neighborhood Hits	431	Shared Neighborhood Hits	165
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

E41L2_HUMAN
NC score	0.015234 (rank : 2314)	θ value	1.38821 (rank : 1840)
Query Neighborhood Hits	2923	Target Neighborhood Hits	287	Shared Neighborhood Hits	150
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

CO1A1_HUMAN
NC score	0.015234 (rank : 2315)	θ value	4.03905 (rank : 2266)
Query Neighborhood Hits	2923	Target Neighborhood Hits	475	Shared Neighborhood Hits	138
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

ATF2_HUMAN
NC score	0.015110 (rank : 2316)	θ value	0.62314 (rank : 1651)
Query Neighborhood Hits	2923	Target Neighborhood Hits	402	Shared Neighborhood Hits	111
SwissProt Accessions	P15336, Q13000	Gene names	ATF2, CREB2, CREBP1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (HB16).

LRCH4_HUMAN
NC score	0.015032 (rank : 2317)	θ value	8.99809 (rank : 2826)
Query Neighborhood Hits	2923	Target Neighborhood Hits	305	Shared Neighborhood Hits	70
SwissProt Accessions	O75427, Q8WV85, Q96ID0	Gene names	LRCH4, LRN, LRRN4
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 4 (Leucine-rich neuronal protein).

EPOR_MOUSE
NC score	0.015008 (rank : 2318)	θ value	1.81305 (rank : 1932)
Query Neighborhood Hits	2923	Target Neighborhood Hits	52	Shared Neighborhood Hits	28
SwissProt Accessions	P14753, Q63852	Gene names	Epor
Domain Architecture
Description	Erythropoietin receptor precursor (EPO-R).

HGS_HUMAN
NC score	0.014992 (rank : 2319)	θ value	1.81305 (rank : 1938)
Query Neighborhood Hits	2923	Target Neighborhood Hits	517	Shared Neighborhood Hits	194
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

CO4A3_HUMAN
NC score	0.014979 (rank : 2320)	θ value	0.365318 (rank : 1543)
Query Neighborhood Hits	2923	Target Neighborhood Hits	421	Shared Neighborhood Hits	113
SwissProt Accessions	Q01955, Q9BQT2	Gene names	COL4A3
Domain Architecture
Description	Collagen alpha-3(IV) chain precursor (Goodpasture antigen).

M6PBP_MOUSE
NC score	0.014967 (rank : 2321)	θ value	0.365318 (rank : 1559)
Query Neighborhood Hits	2923	Target Neighborhood Hits	91	Shared Neighborhood Hits	56
SwissProt Accessions	Q9DBG5, Q3TK05, Q8BKV9, Q9CZK1	Gene names	M6prbp1, Tip47
Domain Architecture	No domain graphic available
Description	Mannose-6-phosphate receptor-binding protein 1 (Cargo selection protein TIP47).

TOP2A_HUMAN
NC score	0.014963 (rank : 2322)	θ value	0.0961366 (rank : 1381)
Query Neighborhood Hits	2923	Target Neighborhood Hits	135	Shared Neighborhood Hits	64
SwissProt Accessions	P11388, Q71UN1, Q9HB24, Q9HB25, Q9HB26, Q9UP44, Q9UQP9	Gene names	TOP2A, TOP2
Domain Architecture
Description	DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme).

NOL1_HUMAN
NC score	0.014943 (rank : 2323)	θ value	2.36792 (rank : 2085)
Query Neighborhood Hits	2923	Target Neighborhood Hits	74	Shared Neighborhood Hits	33
SwissProt Accessions	P46087	Gene names	NOL1
Domain Architecture
Description	Proliferating-cell nucleolar antigen p120 (Proliferation-associated nucleolar protein p120).

SETD8_HUMAN
NC score	0.014922 (rank : 2324)	θ value	2.36792 (rank : 2105)
Query Neighborhood Hits	2923	Target Neighborhood Hits	114	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NQR1, Q86W83, Q8TD09	Gene names	SETD8, PRSET7, SET07, SET8
Domain Architecture
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8) (PR/SET domain-containing protein 07) (PR/SET07) (PR-Set7).

COFA1_MOUSE
NC score	0.014921 (rank : 2325)	θ value	2.36792 (rank : 2033)
Query Neighborhood Hits	2923	Target Neighborhood Hits	305	Shared Neighborhood Hits	88
SwissProt Accessions	O35206, Q9EQD9	Gene names	Col15a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV)].

NEBU_HUMAN
NC score	0.014889 (rank : 2326)	θ value	6.88961 (rank : 2657)
Query Neighborhood Hits	2923	Target Neighborhood Hits	420	Shared Neighborhood Hits	149
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

CNGB1_HUMAN
NC score	0.014830 (rank : 2327)	θ value	6.88961 (rank : 2571)
Query Neighborhood Hits	2923	Target Neighborhood Hits	222	Shared Neighborhood Hits	98
SwissProt Accessions	Q14028, Q14029	Gene names	CNGB1, CNCG4
Domain Architecture
Description	Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).

SYNP2_MOUSE
NC score	0.014813 (rank : 2328)	θ value	3.0926 (rank : 2226)
Query Neighborhood Hits	2923	Target Neighborhood Hits	252	Shared Neighborhood Hits	95
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

HS105_MOUSE
NC score	0.014797 (rank : 2329)	θ value	0.0961366 (rank : 1365)
Query Neighborhood Hits	2923	Target Neighborhood Hits	129	Shared Neighborhood Hits	71
SwissProt Accessions	Q61699, Q3TNS2, Q3UIY8, Q62578, Q62579, Q6A0A5, Q8C430, Q8VCW6	Gene names	Hsph1, Hsp105, Hsp110, Kiaa0201
Domain Architecture
Description	Heat-shock protein 105 kDa (Heat shock-related 100 kDa protein E7I) (HSP-E7I) (Heat shock 110 kDa protein) (42 degrees C-HSP).

CHD9_MOUSE
NC score	0.014743 (rank : 2330)	θ value	0.0563607 (rank : 1306)
Query Neighborhood Hits	2923	Target Neighborhood Hits	427	Shared Neighborhood Hits	165
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

SENP7_HUMAN
NC score	0.014739 (rank : 2331)	θ value	0.62314 (rank : 1691)
Query Neighborhood Hits	2923	Target Neighborhood Hits	97	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BQF6, Q96PS5, Q9C0F6, Q9HBT5	Gene names	SENP7, KIAA1707, SSP2, SUSP2
Domain Architecture
Description	Sentrin-specific protease 7 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP7) (SUMO-1-specific protease 2).

HM20A_HUMAN
NC score	0.014723 (rank : 2332)	θ value	2.36792 (rank : 2055)
Query Neighborhood Hits	2923	Target Neighborhood Hits	343	Shared Neighborhood Hits	155
SwissProt Accessions	Q9NP66, Q53G31, Q9NSF6	Gene names	HMG20A, HMGX1
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (HMG domain-containing protein HMGX1).

GAK4_HUMAN
NC score	0.014703 (rank : 2333)	θ value	0.21417 (rank : 1463)
Query Neighborhood Hits	2923	Target Neighborhood Hits	415	Shared Neighborhood Hits	147
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAB1_HUMAN
NC score	0.014678 (rank : 2334)	θ value	1.81305 (rank : 1936)
Query Neighborhood Hits	2923	Target Neighborhood Hits	279	Shared Neighborhood Hits	106
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

K0562_MOUSE
NC score	0.014674 (rank : 2335)	θ value	0.47712 (rank : 1608)
Query Neighborhood Hits	2923	Target Neighborhood Hits	86	Shared Neighborhood Hits	39
SwissProt Accessions	Q80V31, Q6ZQ95	Gene names	Kiaa0562
Domain Architecture	No domain graphic available
Description	Protein KIAA0562.

UROL1_MOUSE
NC score	0.014621 (rank : 2336)	θ value	1.81305 (rank : 2006)
Query Neighborhood Hits	2923	Target Neighborhood Hits	235	Shared Neighborhood Hits	60
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

GAK11_HUMAN
NC score	0.014620 (rank : 2337)	θ value	0.21417 (rank : 1461)
Query Neighborhood Hits	2923	Target Neighborhood Hits	409	Shared Neighborhood Hits	144
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

ANR25_MOUSE
NC score	0.014600 (rank : 2338)	θ value	1.81305 (rank : 1908)
Query Neighborhood Hits	2923	Target Neighborhood Hits	398	Shared Neighborhood Hits	102
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

GAK5_HUMAN
NC score	0.014584 (rank : 2339)	θ value	0.21417 (rank : 1464)
Query Neighborhood Hits	2923	Target Neighborhood Hits	429	Shared Neighborhood Hits	145
SwissProt Accessions	P62684	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K113 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

RM40_MOUSE
NC score	0.014561 (rank : 2340)	θ value	0.47712 (rank : 1629)
Query Neighborhood Hits	2923	Target Neighborhood Hits	30	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Z2Q5, Q9CS52	Gene names	Mrpl40, Nlvcf
Domain Architecture	No domain graphic available
Description	39S ribosomal protein L40, mitochondrial precursor (L40mt) (MRP-40) (Nuclear localization signal-containing protein deleted in velocardiofacial syndrome homolog).

HCN2_HUMAN
NC score	0.014526 (rank : 2341)	θ value	8.99809 (rank : 2793)
Query Neighborhood Hits	2923	Target Neighborhood Hits	369	Shared Neighborhood Hits	145
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

SPESP_MOUSE
NC score	0.014522 (rank : 2342)	θ value	0.47712 (rank : 1634)
Query Neighborhood Hits	2923	Target Neighborhood Hits	20	Shared Neighborhood Hits	11
SwissProt Accessions	Q9D5A0, Q9D5X8	Gene names	Spesp1
Domain Architecture	No domain graphic available
Description	Sperm equatorial segment protein 1 precursor.

PER1_HUMAN
NC score	0.014473 (rank : 2343)	θ value	3.0926 (rank : 2206)
Query Neighborhood Hits	2923	Target Neighborhood Hits	215	Shared Neighborhood Hits	98
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

TNR6A_HUMAN
NC score	0.014418 (rank : 2344)	θ value	4.03905 (rank : 2362)
Query Neighborhood Hits	2923	Target Neighborhood Hits	343	Shared Neighborhood Hits	126
SwissProt Accessions	Q8NDV7, O15408, Q658L5, Q6NVB5, Q8NEZ0, Q8TBT8, Q8TCR0, Q9NV59, Q9P268	Gene names	TNRC6A, CAGH26, KIAA1460, TNRC6
Domain Architecture	No domain graphic available
Description	Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (Glycine-tryptophan protein of 182 kDa) (GW182 autoantigen) (Protein GW1) (EMSY interactor protein).

SC24A_MOUSE
NC score	0.014397 (rank : 2345)	θ value	5.27518 (rank : 2503)
Query Neighborhood Hits	2923	Target Neighborhood Hits	394	Shared Neighborhood Hits	137
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

GAK6_HUMAN
NC score	0.014369 (rank : 2346)	θ value	0.813845 (rank : 1720)
Query Neighborhood Hits	2923	Target Neighborhood Hits	392	Shared Neighborhood Hits	142
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK2_HUMAN
NC score	0.014244 (rank : 2347)	θ value	0.21417 (rank : 1462)
Query Neighborhood Hits	2923	Target Neighborhood Hits	406	Shared Neighborhood Hits	137
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

CN037_MOUSE
NC score	0.014217 (rank : 2348)	θ value	6.88961 (rank : 2570)
Query Neighborhood Hits	2923	Target Neighborhood Hits	179	Shared Neighborhood Hits	72
SwissProt Accessions	Q8BT18, Q8BFQ7, Q8R1Q5, Q9D6C5	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 homolog precursor.

ESCO2_MOUSE
NC score	0.014201 (rank : 2349)	θ value	1.81305 (rank : 1933)
Query Neighborhood Hits	2923	Target Neighborhood Hits	29	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CIB9, Q3UMT6, Q6IQX5, Q8BNG9, Q8BQF8, Q9CRI8	Gene names	Esco2
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO2 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 2) (ECO1 homolog 2).

ERMAP_HUMAN
NC score	0.014186 (rank : 2350)	θ value	0.279714 (rank : 1495)
Query Neighborhood Hits	2923	Target Neighborhood Hits	155	Shared Neighborhood Hits	69
SwissProt Accessions	Q96PL5, Q5VV53, Q6DUE0, Q7Z3X0, Q8NCV8, Q8NCW2, Q8NCW3, Q96PL6	Gene names	ERMAP, RD, SC
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor (hERMAP) (Scianna blood group antigen) (Radin blood group antigen).

REXO1_MOUSE
NC score	0.014144 (rank : 2351)	θ value	6.88961 (rank : 2682)
Query Neighborhood Hits	2923	Target Neighborhood Hits	166	Shared Neighborhood Hits	76
SwissProt Accessions	Q7TT28, Q3UMP1, Q69ZR0, Q6NSQ6, Q6PI95, Q9DA29	Gene names	Rexo1, Kiaa1138, Tceb3bp1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Transcription elongation factor B polypeptide 3-binding protein 1).

TOP1_HUMAN
NC score	0.014144 (rank : 2352)	θ value	8.99809 (rank : 2902)
Query Neighborhood Hits	2923	Target Neighborhood Hits	207	Shared Neighborhood Hits	102
SwissProt Accessions	P11387, O43256, Q12855, Q12856, Q15610, Q5TFY3, Q9UJN0	Gene names	TOP1
Domain Architecture
Description	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I).

PHF2_HUMAN
NC score	0.014128 (rank : 2353)	θ value	8.99809 (rank : 2855)
Query Neighborhood Hits	2923	Target Neighborhood Hits	208	Shared Neighborhood Hits	91
SwissProt Accessions	O75151, Q8N3K2, Q9Y6N4	Gene names	PHF2, KIAA0662
Domain Architecture
Description	PHD finger protein 2 (GRC5).

WDR46_MOUSE
NC score	0.014121 (rank : 2354)	θ value	1.38821 (rank : 1896)
Query Neighborhood Hits	2923	Target Neighborhood Hits	243	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Z0H1	Gene names	Wdr46, Bing4
Domain Architecture
Description	WD repeat protein 46 (WD repeat protein BING4).

AMRP_HUMAN
NC score	0.014119 (rank : 2355)	θ value	3.0926 (rank : 2126)
Query Neighborhood Hits	2923	Target Neighborhood Hits	126	Shared Neighborhood Hits	62
SwissProt Accessions	P30533	Gene names	LRPAP1, A2MRAP
Domain Architecture
Description	Alpha-2-macroglobulin receptor-associated protein precursor (Alpha-2- MRAP) (Low density lipoprotein receptor-related protein-associated protein 1) (RAP).

ATF2_MOUSE
NC score	0.014049 (rank : 2356)	θ value	0.62314 (rank : 1652)
Query Neighborhood Hits	2923	Target Neighborhood Hits	397	Shared Neighborhood Hits	108
SwissProt Accessions	P16951, Q64089, Q64090, Q64091	Gene names	Atf2
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (MXBP protein).

PAPOG_MOUSE
NC score	0.014042 (rank : 2357)	θ value	0.0113563 (rank : 1205)
Query Neighborhood Hits	2923	Target Neighborhood Hits	103	Shared Neighborhood Hits	46
SwissProt Accessions	Q6PCL9, Q8BZC9	Gene names	Papolg
Domain Architecture	No domain graphic available
Description	Poly(A) polymerase gamma (EC 2.7.7.19) (PAP gamma) (Polynucleotide adenylyltransferase gamma) (SRP RNA 3' adenylating enzyme).

ASTN_MOUSE
NC score	0.014042 (rank : 2358)	θ value	0.365318 (rank : 1535)
Query Neighborhood Hits	2923	Target Neighborhood Hits	98	Shared Neighborhood Hits	23
SwissProt Accessions	Q61137, Q505A0, Q7TQG3, Q8CHH2	Gene names	Astn, Astn1, Kiaa0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor (Neuronal migration protein GC14).

CCNB3_MOUSE
NC score	0.014000 (rank : 2359)	θ value	3.0926 (rank : 2143)
Query Neighborhood Hits	2923	Target Neighborhood Hits	211	Shared Neighborhood Hits	100
SwissProt Accessions	Q810T2, Q810T3, Q8VDC8	Gene names	Ccnb3, Cycb3
Domain Architecture
Description	G2/mitotic-specific cyclin-B3.

CCD47_HUMAN
NC score	0.013995 (rank : 2360)	θ value	3.0926 (rank : 2142)
Query Neighborhood Hits	2923	Target Neighborhood Hits	119	Shared Neighborhood Hits	48
SwissProt Accessions	Q96A33, Q96D00, Q96JZ7, Q9H3E4, Q9NRG3	Gene names	CCDC47
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor.

HUWE1_MOUSE
NC score	0.013992 (rank : 2361)	θ value	0.21417 (rank : 1467)
Query Neighborhood Hits	2923	Target Neighborhood Hits	406	Shared Neighborhood Hits	150
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

RMP_HUMAN
NC score	0.013938 (rank : 2362)	θ value	1.38821 (rank : 1879)
Query Neighborhood Hits	2923	Target Neighborhood Hits	40	Shared Neighborhood Hits	17
SwissProt Accessions	O94763	Gene names	RMP, C19orf2
Domain Architecture
Description	RNA polymerase II subunit 5-mediating protein (RPB5-mediating protein).

PML_HUMAN
NC score	0.013884 (rank : 2363)	θ value	0.47712 (rank : 1624)
Query Neighborhood Hits	2923	Target Neighborhood Hits	248	Shared Neighborhood Hits	82
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

SYAP1_HUMAN
NC score	0.013754 (rank : 2364)	θ value	1.81305 (rank : 1990)
Query Neighborhood Hits	2923	Target Neighborhood Hits	58	Shared Neighborhood Hits	33
SwissProt Accessions	Q96A49, Q96C60, Q96JQ6, Q96T20	Gene names	SYAP1
Domain Architecture
Description	Synapse-associated protein 1.

SEM4C_MOUSE
NC score	0.013648 (rank : 2365)	θ value	0.0736092 (rank : 1353)
Query Neighborhood Hits	2923	Target Neighborhood Hits	77	Shared Neighborhood Hits	34
SwissProt Accessions	Q64151	Gene names	Sema4c, Semacl1, Semai
Domain Architecture
Description	Semaphorin-4C precursor (Semaphorin I) (Sema I) (Semaphorin C-like 1) (M-Sema F).

HGS_MOUSE
NC score	0.013613 (rank : 2366)	θ value	8.99809 (rank : 2794)
Query Neighborhood Hits	2923	Target Neighborhood Hits	589	Shared Neighborhood Hits	220
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

CO8A2_HUMAN
NC score	0.013586 (rank : 2367)	θ value	0.21417 (rank : 1450)
Query Neighborhood Hits	2923	Target Neighborhood Hits	299	Shared Neighborhood Hits	92
SwissProt Accessions	P25067, Q8TEJ5	Gene names	COL8A2
Domain Architecture
Description	Collagen alpha-2(VIII) chain precursor (Endothelial collagen).

E41L3_MOUSE
NC score	0.013533 (rank : 2368)	θ value	0.163984 (rank : 1414)
Query Neighborhood Hits	2923	Target Neighborhood Hits	250	Shared Neighborhood Hits	118
SwissProt Accessions	Q9WV92, Q9R102	Gene names	Epb41l3, Dal1, Epb4.1l3
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1).

IL5RA_MOUSE
NC score	0.013532 (rank : 2369)	θ value	1.06291 (rank : 1790)
Query Neighborhood Hits	2923	Target Neighborhood Hits	33	Shared Neighborhood Hits	18
SwissProt Accessions	P21183	Gene names	Il5ra, Il5r
Domain Architecture	No domain graphic available
Description	Interleukin-5 receptor alpha chain precursor (IL-5R-alpha) (CD125 antigen).

ICB1_MOUSE
NC score	0.013453 (rank : 2370)	θ value	0.163984 (rank : 1421)
Query Neighborhood Hits	2923	Target Neighborhood Hits	69	Shared Neighborhood Hits	37
SwissProt Accessions	Q91YX0	Gene names	Icb1
Domain Architecture	No domain graphic available
Description	Induced by contact to basement membrane 1 protein homolog (ICB-1 protein).

NKTR_HUMAN
NC score	0.013444 (rank : 2371)	θ value	8.99809 (rank : 2844)
Query Neighborhood Hits	2923	Target Neighborhood Hits	658	Shared Neighborhood Hits	241
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

SNUT3_MOUSE
NC score	0.013382 (rank : 2372)	θ value	5.27518 (rank : 2516)
Query Neighborhood Hits	2923	Target Neighborhood Hits	50	Shared Neighborhood Hits	26
SwissProt Accessions	Q8K194, Q8BRA8, Q9CSV0	Gene names
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 3.

SUSD1_HUMAN
NC score	0.013370 (rank : 2373)	θ value	8.99809 (rank : 2889)
Query Neighborhood Hits	2923	Target Neighborhood Hits	285	Shared Neighborhood Hits	63
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

SYYC_MOUSE
NC score	0.013326 (rank : 2374)	θ value	0.163984 (rank : 1436)
Query Neighborhood Hits	2923	Target Neighborhood Hits	27	Shared Neighborhood Hits	8
SwissProt Accessions	Q91WQ3, Q3TEC8, Q3U9A1, Q3UTA7, Q8BVT2, Q8C183	Gene names	Yars
Domain Architecture	No domain graphic available
Description	Tyrosyl-tRNA synthetase, cytoplasmic (EC 6.1.1.1) (Tyrosyl--tRNA ligase) (TyrRS).

GAK10_HUMAN
NC score	0.013318 (rank : 2375)	θ value	0.21417 (rank : 1460)
Query Neighborhood Hits	2923	Target Neighborhood Hits	289	Shared Neighborhood Hits	109
SwissProt Accessions	P87889, P10263, P10264, Q69385, Q9UKH6	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q33.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K10 Gag protein) (HERV-K107 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

CO9A3_HUMAN
NC score	0.013310 (rank : 2376)	θ value	1.38821 (rank : 1831)
Query Neighborhood Hits	2923	Target Neighborhood Hits	361	Shared Neighborhood Hits	92
SwissProt Accessions	Q14050, Q13681, Q9H4G9, Q9UPE2	Gene names	COL9A3
Domain Architecture	No domain graphic available
Description	Collagen alpha-3(IX) chain precursor.

HCN2_MOUSE
NC score	0.013245 (rank : 2377)	θ value	0.62314 (rank : 1671)
Query Neighborhood Hits	2923	Target Neighborhood Hits	278	Shared Neighborhood Hits	129
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

ASTN_HUMAN
NC score	0.013235 (rank : 2378)	θ value	0.62314 (rank : 1649)
Query Neighborhood Hits	2923	Target Neighborhood Hits	105	Shared Neighborhood Hits	23
SwissProt Accessions	O14525, O60799, Q5W0V7, Q5W0V8	Gene names	ASTN, ASTN1, KIAA0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor.

FA13C_HUMAN
NC score	0.013227 (rank : 2379)	θ value	3.0926 (rank : 2166)
Query Neighborhood Hits	2923	Target Neighborhood Hits	94	Shared Neighborhood Hits	51
SwissProt Accessions	Q8NE31, Q99787	Gene names	FAM13C1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

U235_HUMAN
NC score	0.013178 (rank : 2380)	θ value	0.813845 (rank : 1758)
Query Neighborhood Hits	2923	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WUR7	Gene names	C15orf40
Domain Architecture
Description	UPF0235 protein C15orf40.

SYUG_HUMAN
NC score	0.013096 (rank : 2381)	θ value	0.813845 (rank : 1750)
Query Neighborhood Hits	2923	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	O76070, O15104, Q96P61	Gene names	SNCG, BCSG1, PERSYN, PRSN
Domain Architecture
Description	Gamma-synuclein (Persyn) (Breast cancer-specific gene 1 protein) (Synoretin) (SR).

PDCD1_MOUSE
NC score	0.013077 (rank : 2382)	θ value	4.03905 (rank : 2330)
Query Neighborhood Hits	2923	Target Neighborhood Hits	28	Shared Neighborhood Hits	14
SwissProt Accessions	Q02242	Gene names	Pdcd1, Pd1
Domain Architecture
Description	Programmed cell death protein 1 precursor (Protein PD-1) (mPD-1) (CD279 antigen).

CI078_HUMAN
NC score	0.013043 (rank : 2383)	θ value	3.0926 (rank : 2147)
Query Neighborhood Hits	2923	Target Neighborhood Hits	66	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NZ63, Q8WVU6, Q9NT39	Gene names	C9orf78
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf78 (Hepatocellular carcinoma-associated antigen 59).

GAK12_HUMAN
NC score	0.013008 (rank : 2384)	θ value	0.62314 (rank : 1666)
Query Neighborhood Hits	2923	Target Neighborhood Hits	374	Shared Neighborhood Hits	130
SwissProt Accessions	P63130, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K102 Gag protein) (HERV-K(III) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

RAD21_MOUSE
NC score	0.012990 (rank : 2385)	θ value	3.0926 (rank : 2214)
Query Neighborhood Hits	2923	Target Neighborhood Hits	59	Shared Neighborhood Hits	34
SwissProt Accessions	Q61550, P70219, Q91VB9, Q9DBU4	Gene names	Rad21, Hr21
Domain Architecture
Description	Double-strand-break repair protein rad21 homolog (Pokeweed agglutinin- binding protein 29) (PW29) (SCC1 homolog).

ENKUR_HUMAN
NC score	0.012975 (rank : 2386)	θ value	1.38821 (rank : 1842)
Query Neighborhood Hits	2923	Target Neighborhood Hits	64	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TC29	Gene names	C10orf63
Domain Architecture	No domain graphic available
Description	Enkurin.

DYN1_HUMAN
NC score	0.012933 (rank : 2387)	θ value	3.0926 (rank : 2157)
Query Neighborhood Hits	2923	Target Neighborhood Hits	216	Shared Neighborhood Hits	99
SwissProt Accessions	Q05193	Gene names	DNM1, DNM
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

H12_MOUSE
NC score	0.012850 (rank : 2388)	θ value	5.27518 (rank : 2434)
Query Neighborhood Hits	2923	Target Neighborhood Hits	52	Shared Neighborhood Hits	30
SwissProt Accessions	P15864	Gene names	Hist1h1c, H1f2
Domain Architecture
Description	Histone H1.2 (H1 VAR.1) (H1c).

NADAP_HUMAN
NC score	0.012842 (rank : 2389)	θ value	6.88961 (rank : 2656)
Query Neighborhood Hits	2923	Target Neighborhood Hits	208	Shared Neighborhood Hits	99
SwissProt Accessions	Q9BWU0, Q4KMT1, Q4KMX0, Q7Z5Q9, Q9NVN2	Gene names	SLC4A1AP, HLC3
Domain Architecture	No domain graphic available
Description	Kanadaptin (Kidney anion exchanger adapter protein) (Solute carrier family 4 anion exchanger member 1 adapter protein) (Lung cancer oncogene 3 protein).

PSCBP_MOUSE
NC score	0.012782 (rank : 2390)	θ value	6.88961 (rank : 2677)
Query Neighborhood Hits	2923	Target Neighborhood Hits	118	Shared Neighborhood Hits	27
SwissProt Accessions	Q91VY6, Q3TZH1, Q8R4T4, Q9QZA9	Gene names	Pscdbp
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (Cbp).

SEM3F_MOUSE
NC score	0.012673 (rank : 2391)	θ value	2.36792 (rank : 2103)
Query Neighborhood Hits	2923	Target Neighborhood Hits	86	Shared Neighborhood Hits	41
SwissProt Accessions	O88632, O88633	Gene names	Sema3f
Domain Architecture
Description	Semaphorin-3F precursor (Semaphorin IV) (Sema IV).

SYYC_HUMAN
NC score	0.012622 (rank : 2392)	θ value	0.21417 (rank : 1479)
Query Neighborhood Hits	2923	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	P54577, O43276, Q53EN1	Gene names	YARS
Domain Architecture
Description	Tyrosyl-tRNA synthetase, cytoplasmic (EC 6.1.1.1) (Tyrosyl--tRNA ligase) (TyrRS).

TRIM8_MOUSE
NC score	0.012596 (rank : 2393)	θ value	3.0926 (rank : 2228)
Query Neighborhood Hits	2923	Target Neighborhood Hits	674	Shared Neighborhood Hits	225
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

K1219_HUMAN
NC score	0.012590 (rank : 2394)	θ value	0.163984 (rank : 1423)
Query Neighborhood Hits	2923	Target Neighborhood Hits	85	Shared Neighborhood Hits	35
SwissProt Accessions	Q86X10, Q5TG31, Q8N3D1, Q8WWC0, Q9H3X8, Q9UJR1, Q9ULK1, Q9Y3G9	Gene names	KIAA1219
Domain Architecture	No domain graphic available
Description	Protein KIAA1219.

5NT1B_MOUSE
NC score	0.012581 (rank : 2395)	θ value	2.36792 (rank : 2009)
Query Neighborhood Hits	2923	Target Neighborhood Hits	78	Shared Neighborhood Hits	46
SwissProt Accessions	Q91YE9, Q91Y48	Gene names	Nt5c1b, Airp
Domain Architecture
Description	Cytosolic 5'-nucleotidase 1B (EC 3.1.3.5) (Cytosolic 5'-nucleotidase IB) (cN1B) (cN-IB) (Autoimmune infertility-related protein).

VINC_HUMAN
NC score	0.012579 (rank : 2396)	θ value	3.0926 (rank : 2237)
Query Neighborhood Hits	2923	Target Neighborhood Hits	145	Shared Neighborhood Hits	88
SwissProt Accessions	P18206, Q16450, Q5SWX2, Q7Z3B8, Q8IXU7	Gene names	VCL
Domain Architecture
Description	Vinculin (Metavinculin).

AKAP1_MOUSE
NC score	0.012578 (rank : 2397)	θ value	0.813845 (rank : 1702)
Query Neighborhood Hits	2923	Target Neighborhood Hits	198	Shared Neighborhood Hits	71
SwissProt Accessions	O08715, O08714, P97488	Gene names	Akap1, Akap
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein) (S-AKAP).

HERC2_MOUSE
NC score	0.012574 (rank : 2398)	θ value	1.06291 (rank : 1782)
Query Neighborhood Hits	2923	Target Neighborhood Hits	167	Shared Neighborhood Hits	43
SwissProt Accessions	Q4U2R1, O88473, Q3TRJ8, Q3TS47, Q3TST2, Q3UFQ6, Q3URH7, Q5DU32, Q7TPR5, Q80VV7, Q9QYT1, Q9Z168, Q9Z171	Gene names	Herc2, jdf2, Kiaa0393, rjs
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

CLGN_MOUSE
NC score	0.012549 (rank : 2399)	θ value	0.47712 (rank : 1597)
Query Neighborhood Hits	2923	Target Neighborhood Hits	142	Shared Neighborhood Hits	55
SwissProt Accessions	P52194, Q9D2K5	Gene names	Clgn, Meg1
Domain Architecture
Description	Calmegin precursor (MEG 1 antigen) (Calnexin-T) (A2/6).

MYPT2_HUMAN
NC score	0.012527 (rank : 2400)	θ value	6.88961 (rank : 2654)
Query Neighborhood Hits	2923	Target Neighborhood Hits	707	Shared Neighborhood Hits	253
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

B2L13_MOUSE
NC score	0.012523 (rank : 2401)	θ value	0.813845 (rank : 1703)
Query Neighborhood Hits	2923	Target Neighborhood Hits	58	Shared Neighborhood Hits	22
SwissProt Accessions	P59017	Gene names	Bcl2l13, Mil1
Domain Architecture	No domain graphic available
Description	Bcl-2-like 13 protein (Protein Mil1) (Bcl-rambo).

TAB3_HUMAN
NC score	0.012477 (rank : 2402)	θ value	8.99809 (rank : 2893)
Query Neighborhood Hits	2923	Target Neighborhood Hits	168	Shared Neighborhood Hits	67
SwissProt Accessions	Q8N5C8, Q6VQR0	Gene names	MAP3K7IP3, TAB3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3) (NF-kappa-B-activating protein 1).

PGCB_HUMAN
NC score	0.012477 (rank : 2403)	θ value	3.0926 (rank : 2207)
Query Neighborhood Hits	2923	Target Neighborhood Hits	478	Shared Neighborhood Hits	142
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

SOX13_MOUSE
NC score	0.012468 (rank : 2404)	θ value	0.47712 (rank : 1633)
Query Neighborhood Hits	2923	Target Neighborhood Hits	495	Shared Neighborhood Hits	166
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

HUWE1_HUMAN
NC score	0.012384 (rank : 2405)	θ value	1.06291 (rank : 1785)
Query Neighborhood Hits	2923	Target Neighborhood Hits	443	Shared Neighborhood Hits	163
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

INP5E_HUMAN
NC score	0.012342 (rank : 2406)	θ value	1.81305 (rank : 1945)
Query Neighborhood Hits	2923	Target Neighborhood Hits	201	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NRR6, Q15734	Gene names	INPP5E
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

BAZ1B_MOUSE
NC score	0.012319 (rank : 2407)	θ value	8.99809 (rank : 2735)
Query Neighborhood Hits	2923	Target Neighborhood Hits	394	Shared Neighborhood Hits	182
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

SRBP1_MOUSE
NC score	0.012207 (rank : 2408)	θ value	5.27518 (rank : 2519)
Query Neighborhood Hits	2923	Target Neighborhood Hits	384	Shared Neighborhood Hits	117
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

SYNP2_HUMAN
NC score	0.012175 (rank : 2409)	θ value	2.36792 (rank : 2107)
Query Neighborhood Hits	2923	Target Neighborhood Hits	323	Shared Neighborhood Hits	118
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

SEMG1_HUMAN
NC score	0.012144 (rank : 2410)	θ value	5.27518 (rank : 2507)
Query Neighborhood Hits	2923	Target Neighborhood Hits	200	Shared Neighborhood Hits	86
SwissProt Accessions	P04279, Q6X4I9, Q6Y809, Q6Y822, Q6Y823, Q86U64, Q96QM3	Gene names	SEMG1, SEMG
Domain Architecture
Description	Semenogelin-1 precursor (Semenogelin I) (SGI) [Contains: Alpha- inhibin-92; Alpha-inhibin-31; Seminal basic protein].

SEPT8_HUMAN
NC score	0.012086 (rank : 2411)	θ value	2.36792 (rank : 2104)
Query Neighborhood Hits	2923	Target Neighborhood Hits	290	Shared Neighborhood Hits	149
SwissProt Accessions	Q92599, Q8IX36, Q8IX37, Q9BVB3	Gene names	SEPT8, KIAA0202
Domain Architecture
Description	Septin-8.

AINX_MOUSE
NC score	0.012085 (rank : 2412)	θ value	5.27518 (rank : 2380)
Query Neighborhood Hits	2923	Target Neighborhood Hits	448	Shared Neighborhood Hits	196
SwissProt Accessions	P46660, Q61958, Q8VCW5	Gene names	Ina
Domain Architecture
Description	Alpha-internexin (Alpha-Inx) (66 kDa neurofilament protein) (Neurofilament-66) (NF-66).

MYRIP_MOUSE
NC score	0.012058 (rank : 2413)	θ value	3.0926 (rank : 2194)
Query Neighborhood Hits	2923	Target Neighborhood Hits	207	Shared Neighborhood Hits	86
SwissProt Accessions	Q8K3I4, Q8CFC0, Q8K4H5	Gene names	Myrip, Slac2c
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

NOG2_HUMAN
NC score	0.012006 (rank : 2414)	θ value	3.0926 (rank : 2198)
Query Neighborhood Hits	2923	Target Neighborhood Hits	117	Shared Neighborhood Hits	67
SwissProt Accessions	Q13823, Q9BWN7	Gene names	GNL2, NGP1
Domain Architecture
Description	Nucleolar GTP-binding protein 2 (Autoantigen NGP-1).

IL4RA_MOUSE
NC score	0.011998 (rank : 2415)	θ value	4.03905 (rank : 2296)
Query Neighborhood Hits	2923	Target Neighborhood Hits	194	Shared Neighborhood Hits	80
SwissProt Accessions	P16382, O54690, Q60583, Q8CBW5	Gene names	Il4r, Il4ra
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (IL-4- binding protein) (IL4-BP)].

MANS1_MOUSE
NC score	0.011991 (rank : 2416)	θ value	1.81305 (rank : 1958)
Query Neighborhood Hits	2923	Target Neighborhood Hits	19	Shared Neighborhood Hits	9
SwissProt Accessions	Q9CR33, Q80V71	Gene names	Mansc1
Domain Architecture	No domain graphic available
Description	MANSC domain-containing protein 1 precursor.

CO5A3_HUMAN
NC score	0.011848 (rank : 2417)	θ value	1.81305 (rank : 1921)
Query Neighborhood Hits	2923	Target Neighborhood Hits	433	Shared Neighborhood Hits	112
SwissProt Accessions	P25940, Q9NZQ6	Gene names	COL5A3
Domain Architecture
Description	Collagen alpha-3(V) chain precursor.

LRP11_MOUSE
NC score	0.011743 (rank : 2418)	θ value	3.0926 (rank : 2187)
Query Neighborhood Hits	2923	Target Neighborhood Hits	81	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CB67, Q8C7Y7	Gene names	Lrp11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.

RNF25_HUMAN
NC score	0.011728 (rank : 2419)	θ value	4.03905 (rank : 2345)
Query Neighborhood Hits	2923	Target Neighborhood Hits	163	Shared Neighborhood Hits	57
SwissProt Accessions	Q96BH1, Q9H874	Gene names	RNF25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-).

ZO2_MOUSE
NC score	0.011696 (rank : 2420)	θ value	0.163984 (rank : 1439)
Query Neighborhood Hits	2923	Target Neighborhood Hits	296	Shared Neighborhood Hits	83
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

ATS19_HUMAN
NC score	0.011667 (rank : 2421)	θ value	0.0431538 (rank : 1279)
Query Neighborhood Hits	2923	Target Neighborhood Hits	203	Shared Neighborhood Hits	54
SwissProt Accessions	Q8TE59	Gene names	ADAMTS19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

GOPC_HUMAN
NC score	0.011641 (rank : 2422)	θ value	1.06291 (rank : 1781)
Query Neighborhood Hits	2923	Target Neighborhood Hits	377	Shared Neighborhood Hits	145
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

FA13C_MOUSE
NC score	0.011574 (rank : 2423)	θ value	0.365318 (rank : 1548)
Query Neighborhood Hits	2923	Target Neighborhood Hits	79	Shared Neighborhood Hits	34
SwissProt Accessions	Q9DBR2	Gene names	Fam13c1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

TOP1_MOUSE
NC score	0.011571 (rank : 2424)	θ value	8.99809 (rank : 2903)
Query Neighborhood Hits	2923	Target Neighborhood Hits	213	Shared Neighborhood Hits	95
SwissProt Accessions	Q04750	Gene names	Top1, Top-1
Domain Architecture
Description	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I).

SMPX_MOUSE
NC score	0.011552 (rank : 2425)	θ value	4.03905 (rank : 2357)
Query Neighborhood Hits	2923	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	Q9DC77, Q4QRM9, Q8CEX8, Q9ER98	Gene names	Smpx, Csl
Domain Architecture	No domain graphic available
Description	Small muscular protein (Stretch-responsive skeletal muscle protein) (Chisel protein).

CC025_HUMAN
NC score	0.011490 (rank : 2426)	θ value	1.38821 (rank : 1826)
Query Neighborhood Hits	2923	Target Neighborhood Hits	31	Shared Neighborhood Hits	16
SwissProt Accessions	Q6NXP0, Q69YX4	Gene names	C3orf25
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf25.

TRI17_MOUSE
NC score	0.011469 (rank : 2427)	θ value	0.365318 (rank : 1575)
Query Neighborhood Hits	2923	Target Neighborhood Hits	620	Shared Neighborhood Hits	263
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

IF31_HUMAN
NC score	0.011453 (rank : 2428)	θ value	8.99809 (rank : 2799)
Query Neighborhood Hits	2923	Target Neighborhood Hits	87	Shared Neighborhood Hits	53
SwissProt Accessions	O75822, Q9BUD2, Q9H8Q2, Q9UI65	Gene names	EIF3S1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 3 subunit 1 (eIF-3 alpha) (eIF3 p35) (eIF3j).

SORC2_HUMAN
NC score	0.011413 (rank : 2429)	θ value	2.36792 (rank : 2106)
Query Neighborhood Hits	2923	Target Neighborhood Hits	66	Shared Neighborhood Hits	26
SwissProt Accessions	Q96PQ0, Q9P2L7	Gene names	SORCS2, KIAA1329
Domain Architecture
Description	VPS10 domain-containing receptor SorCS2 precursor.

FHOD1_MOUSE
NC score	0.011394 (rank : 2430)	θ value	8.99809 (rank : 2781)
Query Neighborhood Hits	2923	Target Neighborhood Hits	217	Shared Neighborhood Hits	80
SwissProt Accessions	Q6P9Q4, Q8BMK2	Gene names	Fhod1, Fhos1
Domain Architecture	No domain graphic available
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

HSP74_HUMAN
NC score	0.011360 (rank : 2431)	θ value	1.06291 (rank : 1784)
Query Neighborhood Hits	2923	Target Neighborhood Hits	154	Shared Neighborhood Hits	78
SwissProt Accessions	P34932, O95756	Gene names	HSPA4
Domain Architecture
Description	Heat shock 70 kDa protein 4 (Heat shock 70-related protein APG-2) (HSP70RY).

PACS1_MOUSE
NC score	0.011334 (rank : 2432)	θ value	6.88961 (rank : 2666)
Query Neighborhood Hits	2923	Target Neighborhood Hits	87	Shared Neighborhood Hits	43
SwissProt Accessions	Q8K212, Q6P5H8	Gene names	Pacs1
Domain Architecture	No domain graphic available
Description	Phosphofurin acidic cluster sorting protein 1 (PACS-1).

SF04_HUMAN
NC score	0.011259 (rank : 2433)	θ value	0.47712 (rank : 1630)
Query Neighborhood Hits	2923	Target Neighborhood Hits	83	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IWZ8, O60378, Q6P3X9, Q8TCQ4, Q8WWT4, Q8WWT5, Q9NTG3	Gene names	SF4
Domain Architecture	No domain graphic available
Description	Splicing factor 4 (RNA-binding protein RBP).

PAPOG_HUMAN
NC score	0.011211 (rank : 2434)	θ value	0.0736092 (rank : 1348)
Query Neighborhood Hits	2923	Target Neighborhood Hits	44	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BWT3, Q969N1, Q9H8L2, Q9HAD0	Gene names	PAPOLG, PAP2, PAPG
Domain Architecture
Description	Poly(A) polymerase gamma (EC 2.7.7.19) (PAP gamma) (Polynucleotide adenylyltransferase gamma) (SRP RNA 3' adenylating enzyme) (Neo- poly(A) polymerase) (Neo-PAP).

DTD1_HUMAN
NC score	0.011182 (rank : 2435)	θ value	4.03905 (rank : 2274)
Query Neighborhood Hits	2923	Target Neighborhood Hits	50	Shared Neighborhood Hits	25
SwissProt Accessions	Q8TEA8, Q496D1, Q5W184, Q8WXU8, Q9BW67, Q9H464, Q9H474	Gene names	HARS2, C20orf88
Domain Architecture
Description	Probable D-tyrosyl-tRNA(Tyr) deacylase (EC 3.1.-.-).

DLG7_MOUSE
NC score	0.011178 (rank : 2436)	θ value	0.813845 (rank : 1717)
Query Neighborhood Hits	2923	Target Neighborhood Hits	84	Shared Neighborhood Hits	34
SwissProt Accessions	Q8K4R9, Q6ZQL3, Q80VS7, Q8BUC8, Q8BZ79	Gene names	Dlg7, Kiaa0008
Domain Architecture	No domain graphic available
Description	Discs large homolog 7 (Hepatoma up-regulated protein homolog) (HURP).

PRGC2_MOUSE
NC score	0.011140 (rank : 2437)	θ value	6.88961 (rank : 2675)
Query Neighborhood Hits	2923	Target Neighborhood Hits	225	Shared Neighborhood Hits	78
SwissProt Accessions	Q8VHJ7, Q8C1C0	Gene names	Ppargc1b, Errl1, Pgc1, Pgc1b, Ppargc1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta protein) (PGC-1beta) (ERR ligand 1) (PPARGC-1-beta) (PGC-1-beta).

CALX_HUMAN
NC score	0.011069 (rank : 2438)	θ value	0.813845 (rank : 1709)
Query Neighborhood Hits	2923	Target Neighborhood Hits	96	Shared Neighborhood Hits	45
SwissProt Accessions	P27824	Gene names	CANX
Domain Architecture
Description	Calnexin precursor (Major histocompatibility complex class I antigen- binding protein p88) (p90) (IP90).

NCTR1_HUMAN
NC score	0.011062 (rank : 2439)	θ value	4.03905 (rank : 2324)
Query Neighborhood Hits	2923	Target Neighborhood Hits	44	Shared Neighborhood Hits	24
SwissProt Accessions	O76036, O76016, O76017, O76018	Gene names	NCR1, LY94
Domain Architecture	No domain graphic available
Description	Natural cytotoxicity triggering receptor 1 precursor (Natural killer cell p46-related protein) (NKp46) (hNKp46) (NK-p46) (NK cell- activating receptor) (Lymphocyte antigen 94 homolog) (CD335 antigen).

ATS19_MOUSE
NC score	0.011041 (rank : 2440)	θ value	0.0563607 (rank : 1300)
Query Neighborhood Hits	2923	Target Neighborhood Hits	188	Shared Neighborhood Hits	36
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

GAB1_MOUSE
NC score	0.011036 (rank : 2441)	θ value	5.27518 (rank : 2425)
Query Neighborhood Hits	2923	Target Neighborhood Hits	233	Shared Neighborhood Hits	76
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

SPT6H_MOUSE
NC score	0.011006 (rank : 2442)	θ value	1.38821 (rank : 1890)
Query Neighborhood Hits	2923	Target Neighborhood Hits	104	Shared Neighborhood Hits	43
SwissProt Accessions	Q62383, Q5SYM0, Q6GQS3, Q6ZQI0, Q8BQY6	Gene names	Supt6h, Kiaa0162
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT6.

CT195_MOUSE
NC score	0.011005 (rank : 2443)	θ value	6.88961 (rank : 2578)
Query Neighborhood Hits	2923	Target Neighborhood Hits	15	Shared Neighborhood Hits	9
SwissProt Accessions	Q80WB0	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf195 homolog.

GTF2I_MOUSE
NC score	0.011002 (rank : 2444)	θ value	8.99809 (rank : 2790)
Query Neighborhood Hits	2923	Target Neighborhood Hits	72	Shared Neighborhood Hits	31
SwissProt Accessions	Q9ESZ8, O54700, O55030, O55031, Q8VHD1, Q8VHD2, Q8VHD3, Q8VHD4, Q9CSB5, Q9D9K9	Gene names	Gtf2i, Bap135, Diws1t
Domain Architecture
Description	General transcription factor II-I (GTFII-I) (TFII-I) (Bruton tyrosine kinase-associated protein 135) (BTK-associated protein 135) (BAP-135).

APBA1_HUMAN
NC score	0.011000 (rank : 2445)	θ value	1.38821 (rank : 1821)
Query Neighborhood Hits	2923	Target Neighborhood Hits	325	Shared Neighborhood Hits	79
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

LDB3_MOUSE
NC score	0.010992 (rank : 2446)	θ value	4.03905 (rank : 2305)
Query Neighborhood Hits	2923	Target Neighborhood Hits	510	Shared Neighborhood Hits	170
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

DRP2_HUMAN
NC score	0.010924 (rank : 2447)	θ value	5.27518 (rank : 2414)
Query Neighborhood Hits	2923	Target Neighborhood Hits	186	Shared Neighborhood Hits	91
SwissProt Accessions	Q13474	Gene names	DRP2
Domain Architecture
Description	Dystrophin-related protein 2.

ABCF1_HUMAN
NC score	0.010821 (rank : 2448)	θ value	3.0926 (rank : 2125)
Query Neighborhood Hits	2923	Target Neighborhood Hits	343	Shared Neighborhood Hits	143
SwissProt Accessions	Q8NE71, O14897, Q69YP6	Gene names	ABCF1, ABC50
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50) (TNF-alpha-stimulated ABC protein).

PGCB_MOUSE
NC score	0.010778 (rank : 2449)	θ value	1.81305 (rank : 1969)
Query Neighborhood Hits	2923	Target Neighborhood Hits	459	Shared Neighborhood Hits	113
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

DTNB_HUMAN
NC score	0.010701 (rank : 2450)	θ value	8.99809 (rank : 2771)
Query Neighborhood Hits	2923	Target Neighborhood Hits	255	Shared Neighborhood Hits	133
SwissProt Accessions	O60941, O43782, O60881, O75538, Q9UE14, Q9UE15, Q9UE16	Gene names	DTNB
Domain Architecture
Description	Dystrobrevin beta (Beta-dystrobrevin) (DTN-B).

ENKUR_MOUSE
NC score	0.010650 (rank : 2451)	θ value	5.27518 (rank : 2419)
Query Neighborhood Hits	2923	Target Neighborhood Hits	51	Shared Neighborhood Hits	30
SwissProt Accessions	Q6SP97	Gene names
Domain Architecture	No domain graphic available
Description	Enkurin.

SCAR3_HUMAN
NC score	0.010604 (rank : 2452)	θ value	5.27518 (rank : 2504)
Query Neighborhood Hits	2923	Target Neighborhood Hits	205	Shared Neighborhood Hits	90
SwissProt Accessions	Q6AZY7, Q9UM15, Q9UM16	Gene names	SCARA3, CSR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class A member 3 (Cellular stress response gene protein).

GT2D1_HUMAN
NC score	0.010586 (rank : 2453)	θ value	1.38821 (rank : 1847)
Query Neighborhood Hits	2923	Target Neighborhood Hits	46	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UHL9, O95444, Q75MX7, Q86UM3, Q8WVC4, Q9UHK8, Q9UI91	Gene names	GTF2IRD1, CREAM1, GTF3, MUSTRD1, RBAP2, WBSCR11, WBSCR12
Domain Architecture
Description	General transcription factor II-I repeat domain-containing protein 1 (GTF2I repeat domain-containing protein 1) (Muscle TFII-I repeat domain-containing protein 1) (General transcription factor III) (Slow- muscle-fiber enhancer-binding protein) (USE B1-binding protein) (MusTRD1/BEN) (Williams-Beuren syndrome chromosome region 11 protein).

UROL1_HUMAN
NC score	0.010511 (rank : 2454)	θ value	3.0926 (rank : 2234)
Query Neighborhood Hits	2923	Target Neighborhood Hits	213	Shared Neighborhood Hits	43
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

ARMX2_MOUSE
NC score	0.010495 (rank : 2455)	θ value	8.99809 (rank : 2731)
Query Neighborhood Hits	2923	Target Neighborhood Hits	349	Shared Neighborhood Hits	114
SwissProt Accessions	Q6A058, Q9CXI9	Gene names	Armcx2, Kiaa0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2.

PML_MOUSE
NC score	0.010468 (rank : 2456)	θ value	2.36792 (rank : 2092)
Query Neighborhood Hits	2923	Target Neighborhood Hits	246	Shared Neighborhood Hits	80
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

NFAT5_HUMAN
NC score	0.010462 (rank : 2457)	θ value	0.62314 (rank : 1681)
Query Neighborhood Hits	2923	Target Neighborhood Hits	217	Shared Neighborhood Hits	72
SwissProt Accessions	O94916, O95693, Q9UN18	Gene names	NFAT5, KIAA0827, TONEBP
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T-cell transcription factor NFAT5) (NF-AT5) (Tonicity-responsive enhancer-binding protein) (TonE- binding protein) (TonEBP).

ATS2_MOUSE
NC score	0.010447 (rank : 2458)	θ value	0.0563607 (rank : 1301)
Query Neighborhood Hits	2923	Target Neighborhood Hits	179	Shared Neighborhood Hits	27
SwissProt Accessions	Q8C9W3	Gene names	Adamts2
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

JHD3B_MOUSE
NC score	0.010425 (rank : 2459)	θ value	5.27518 (rank : 2444)
Query Neighborhood Hits	2923	Target Neighborhood Hits	152	Shared Neighborhood Hits	72
SwissProt Accessions	Q91VY5, Q3UR22, Q6ZQ30, Q99K42	Gene names	Jmjd2b, Jhdm3b
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

SEPT8_MOUSE
NC score	0.010365 (rank : 2460)	θ value	5.27518 (rank : 2508)
Query Neighborhood Hits	2923	Target Neighborhood Hits	251	Shared Neighborhood Hits	129
SwissProt Accessions	Q8CHH9, Q80YC7, Q9ESF7	Gene names	Sept8, Kiaa0202
Domain Architecture
Description	Septin-8.

SEM3D_MOUSE
NC score	0.010301 (rank : 2461)	θ value	5.27518 (rank : 2506)
Query Neighborhood Hits	2923	Target Neighborhood Hits	97	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BH34	Gene names	Sema3d
Domain Architecture	No domain graphic available
Description	Semaphorin-3D precursor.

CD3G_MOUSE
NC score	0.010280 (rank : 2462)	θ value	4.03905 (rank : 2262)
Query Neighborhood Hits	2923	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	P11942	Gene names	Cd3g
Domain Architecture
Description	T-cell surface glycoprotein CD3 gamma chain precursor (T-cell receptor T3 gamma chain).

CYH3_MOUSE
NC score	0.010215 (rank : 2463)	θ value	1.38821 (rank : 1834)
Query Neighborhood Hits	2923	Target Neighborhood Hits	148	Shared Neighborhood Hits	44
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

SOX6_MOUSE
NC score	0.010159 (rank : 2464)	θ value	8.99809 (rank : 2885)
Query Neighborhood Hits	2923	Target Neighborhood Hits	341	Shared Neighborhood Hits	160
SwissProt Accessions	P40645, Q62250, Q9QWS5	Gene names	Sox6, Sox-6
Domain Architecture
Description	Transcription factor SOX-6 (SOX-LZ).

LV4C_HUMAN
NC score	0.010141 (rank : 2465)	θ value	1.38821 (rank : 1862)
Query Neighborhood Hits	2923	Target Neighborhood Hits	284	Shared Neighborhood Hits	97
SwissProt Accessions	P01717	Gene names
Domain Architecture	No domain graphic available
Description	Ig lambda chain V-IV region Hil.

CCD60_MOUSE
NC score	0.010118 (rank : 2466)	θ value	1.38821 (rank : 1827)
Query Neighborhood Hits	2923	Target Neighborhood Hits	18	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C4J0, Q6DIA4, Q6PAQ3	Gene names	Ccdc60
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 60.

GOPC_MOUSE
NC score	0.010116 (rank : 2467)	θ value	1.38821 (rank : 1845)
Query Neighborhood Hits	2923	Target Neighborhood Hits	323	Shared Neighborhood Hits	119
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

HSF1_MOUSE
NC score	0.010079 (rank : 2468)	θ value	8.99809 (rank : 2796)
Query Neighborhood Hits	2923	Target Neighborhood Hits	267	Shared Neighborhood Hits	113
SwissProt Accessions	P38532, O70462	Gene names	Hsf1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

TATD2_HUMAN
NC score	0.010066 (rank : 2469)	θ value	5.27518 (rank : 2522)
Query Neighborhood Hits	2923	Target Neighborhood Hits	66	Shared Neighborhood Hits	32
SwissProt Accessions	Q93075	Gene names	TATDN2, KIAA0218
Domain Architecture	No domain graphic available
Description	TatD DNase domain-containing deoxyribonuclease 2 (EC 3.1.21.-).

REPS1_HUMAN
NC score	0.010035 (rank : 2470)	θ value	4.03905 (rank : 2341)
Query Neighborhood Hits	2923	Target Neighborhood Hits	205	Shared Neighborhood Hits	84
SwissProt Accessions	Q96D71, Q8NDR7, Q8WU62, Q9BXY9	Gene names	REPS1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

TTC28_HUMAN
NC score	0.010005 (rank : 2471)	θ value	1.81305 (rank : 2001)
Query Neighborhood Hits	2923	Target Neighborhood Hits	271	Shared Neighborhood Hits	93
SwissProt Accessions	Q96AY4, O95928, O95929, Q9NTE4, Q9UG31, Q9UGG5, Q9UPV8, Q9Y3S5	Gene names	TTC28, KIAA1043
Domain Architecture
Description	Tetratricopeptide repeat protein 28 (TPR repeat protein 28).

DTD1_MOUSE
NC score	0.009981 (rank : 2472)	θ value	4.03905 (rank : 2275)
Query Neighborhood Hits	2923	Target Neighborhood Hits	37	Shared Neighborhood Hits	21
SwissProt Accessions	Q9DD18, Q9CRE8, Q9CYL0, Q9D013, Q9D1G4	Gene names	Hars2
Domain Architecture
Description	Probable D-tyrosyl-tRNA(Tyr) deacylase (EC 3.1.-.-).

SGOL1_HUMAN
NC score	0.009953 (rank : 2473)	θ value	5.27518 (rank : 2512)
Query Neighborhood Hits	2923	Target Neighborhood Hits	62	Shared Neighborhood Hits	30
SwissProt Accessions	Q5FBB7, Q588H5, Q5FBB4, Q5FBB5, Q5FBB6, Q5FBB8, Q8N579, Q8WVL0, Q9BVA8, Q9H275	Gene names	SGOL1, SGO1
Domain Architecture	No domain graphic available
Description	Shugoshin-like 1 (hSgo1) (Serologically defined breast cancer antigen NY-BR-85).

SEM3D_HUMAN
NC score	0.009891 (rank : 2474)	θ value	4.03905 (rank : 2354)
Query Neighborhood Hits	2923	Target Neighborhood Hits	104	Shared Neighborhood Hits	53
SwissProt Accessions	O95025, Q6UW77, Q8NCQ1	Gene names	SEMA3D
Domain Architecture
Description	Semaphorin-3D precursor.

E41L3_HUMAN
NC score	0.009855 (rank : 2475)	θ value	0.21417 (rank : 1455)
Query Neighborhood Hits	2923	Target Neighborhood Hits	113	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y2J2, O95713, Q9BRP5	Gene names	EPB41L3, DAL1, KIAA0987
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1).

MA1B1_HUMAN
NC score	0.009854 (rank : 2476)	θ value	0.0736092 (rank : 1345)
Query Neighborhood Hits	2923	Target Neighborhood Hits	125	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UKM7, Q5VSG3, Q9BRS9, Q9Y5K7	Gene names	MAN1B1
Domain Architecture
Description	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (EC 3.2.1.113) (ER alpha-1,2-mannosidase) (Mannosidase alpha class 1B member 1) (Man9GlcNAc2-specific-processing alpha-mannosidase).

TTC15_MOUSE
NC score	0.009841 (rank : 2477)	θ value	2.36792 (rank : 2114)
Query Neighborhood Hits	2923	Target Neighborhood Hits	113	Shared Neighborhood Hits	32
SwissProt Accessions	Q8K2L8, Q8BX27	Gene names	Ttc15
Domain Architecture
Description	Tetratricopeptide repeat protein 15 (TPR repeat protein 15).

EFHB_MOUSE
NC score	0.009835 (rank : 2478)	θ value	0.365318 (rank : 1547)
Query Neighborhood Hits	2923	Target Neighborhood Hits	120	Shared Neighborhood Hits	32
SwissProt Accessions	Q8CDU5	Gene names	Efhb
Domain Architecture	No domain graphic available
Description	EF-hand domain-containing family member B.

RC3H1_HUMAN
NC score	0.009733 (rank : 2479)	θ value	0.365318 (rank : 1565)
Query Neighborhood Hits	2923	Target Neighborhood Hits	433	Shared Neighborhood Hits	132
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

IL21R_MOUSE
NC score	0.009691 (rank : 2480)	θ value	2.36792 (rank : 2060)
Query Neighborhood Hits	2923	Target Neighborhood Hits	43	Shared Neighborhood Hits	23
SwissProt Accessions	Q9JHX3, Q9ESM1	Gene names	Il21r, Nilr
Domain Architecture	No domain graphic available
Description	Interleukin-21 receptor precursor (IL-21R) (Novel interleukin receptor) (Lymphocyte receptor beta) (LR-beta) (Novel cytokine receptor NR8).

HNF1A_MOUSE
NC score	0.009675 (rank : 2481)	θ value	1.81305 (rank : 1939)
Query Neighborhood Hits	2923	Target Neighborhood Hits	212	Shared Neighborhood Hits	69
SwissProt Accessions	P22361	Gene names	Tcf1, Hnf-1, Hnf-1a, Hnf1a
Domain Architecture
Description	Hepatocyte nuclear factor 1-alpha (HNF-1A) (Liver-specific transcription factor LF-B1) (LFB1).

CO8A2_MOUSE
NC score	0.009661 (rank : 2482)	θ value	0.62314 (rank : 1659)
Query Neighborhood Hits	2923	Target Neighborhood Hits	273	Shared Neighborhood Hits	81
SwissProt Accessions	P25318, Q68ED0, Q6KAQ4, Q6P1C4	Gene names	Col8a2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(VIII) chain precursor (Endothelial collagen).

HD_HUMAN
NC score	0.009656 (rank : 2483)	θ value	6.88961 (rank : 2619)
Query Neighborhood Hits	2923	Target Neighborhood Hits	165	Shared Neighborhood Hits	71
SwissProt Accessions	P42858, Q9UQB7	Gene names	HD, IT15
Domain Architecture
Description	Huntingtin (Huntington disease protein) (HD protein).

GGA1_HUMAN
NC score	0.009600 (rank : 2484)	θ value	8.99809 (rank : 2786)
Query Neighborhood Hits	2923	Target Neighborhood Hits	169	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UJY5, Q5TG07, Q9BW94, Q9UG00, Q9UGW0, Q9UGW1	Gene names	GGA1
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

RAD21_HUMAN
NC score	0.009589 (rank : 2485)	θ value	3.0926 (rank : 2213)
Query Neighborhood Hits	2923	Target Neighborhood Hits	46	Shared Neighborhood Hits	26
SwissProt Accessions	O60216, Q15001, Q99568	Gene names	RAD21, HR21, KIAA0078, NXP1
Domain Architecture
Description	Double-strand-break repair protein rad21 homolog (hHR21) (Nuclear matrix protein 1) (NXP-1) (SCC1 homolog).

CBL_MOUSE
NC score	0.009530 (rank : 2486)	θ value	2.36792 (rank : 2020)
Query Neighborhood Hits	2923	Target Neighborhood Hits	426	Shared Neighborhood Hits	120
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

ASPC1_MOUSE
NC score	0.009526 (rank : 2487)	θ value	4.03905 (rank : 2251)
Query Neighborhood Hits	2923	Target Neighborhood Hits	47	Shared Neighborhood Hits	24
SwissProt Accessions	Q8VBT9, Q3UKD1, Q6V7K5, Q9CT64	Gene names	Aspscr1, Tug
Domain Architecture	No domain graphic available
Description	Tether containing UBX domain for GLUT4 (Alveolar soft part sarcoma chromosome region candidate 1 homolog).

DDEF1_MOUSE
NC score	0.009506 (rank : 2488)	θ value	6.88961 (rank : 2579)
Query Neighborhood Hits	2923	Target Neighborhood Hits	592	Shared Neighborhood Hits	169
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

CBS_HUMAN
NC score	0.009499 (rank : 2489)	θ value	1.38821 (rank : 1825)
Query Neighborhood Hits	2923	Target Neighborhood Hits	21	Shared Neighborhood Hits	6
SwissProt Accessions	P35520, Q99425, Q9BWC5	Gene names	CBS
Domain Architecture
Description	Cystathionine beta-synthase (EC 4.2.1.22) (Serine sulfhydrase) (Beta- thionase).

ASPM_MOUSE
NC score	0.009486 (rank : 2490)	θ value	5.27518 (rank : 2385)
Query Neighborhood Hits	2923	Target Neighborhood Hits	150	Shared Neighborhood Hits	55
SwissProt Accessions	Q8CJ27, O88482, Q8BJI8, Q8BKT4	Gene names	Aspm, Calmbp1, Sha1
Domain Architecture
Description	Abnormal spindle-like microcephaly-associated protein homolog (Calmodulin-binding protein 1) (Spindle and hydroxyurea checkpoint abnormal protein) (Calmodulin-binding protein Sha1).

FA48A_MOUSE
NC score	0.009480 (rank : 2491)	θ value	0.813845 (rank : 1719)
Query Neighborhood Hits	2923	Target Neighborhood Hits	15	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TT00, Q8BG53, Q9JLS9	Gene names	Fam48a, D3Ertd300e
Domain Architecture	No domain graphic available
Description	Protein FAM48A (p38-interacting protein) (p38IP).

VINC_MOUSE
NC score	0.009463 (rank : 2492)	θ value	3.0926 (rank : 2238)
Query Neighborhood Hits	2923	Target Neighborhood Hits	135	Shared Neighborhood Hits	75
SwissProt Accessions	Q64727, Q8BP32, Q8BS46, Q922C5, Q922D9	Gene names	Vcl
Domain Architecture
Description	Vinculin (Metavinculin).

SAPS1_MOUSE
NC score	0.009460 (rank : 2493)	θ value	1.06291 (rank : 1810)
Query Neighborhood Hits	2923	Target Neighborhood Hits	144	Shared Neighborhood Hits	65
SwissProt Accessions	Q7TSI3, Q80TJ4	Gene names	Saps1, Kiaa1115
Domain Architecture	No domain graphic available
Description	SAPS domain family member 1.

CX039_MOUSE
NC score	0.009426 (rank : 2494)	θ value	1.81305 (rank : 1925)
Query Neighborhood Hits	2923	Target Neighborhood Hits	19	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K2D0, Q3U3R2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein CXorf39 homolog.

SCEL_HUMAN
NC score	0.009412 (rank : 2495)	θ value	1.38821 (rank : 1880)
Query Neighborhood Hits	2923	Target Neighborhood Hits	117	Shared Neighborhood Hits	43
SwissProt Accessions	O95171	Gene names	SCEL
Domain Architecture
Description	Sciellin.

SOX13_HUMAN
NC score	0.009384 (rank : 2496)	θ value	0.279714 (rank : 1523)
Query Neighborhood Hits	2923	Target Neighborhood Hits	464	Shared Neighborhood Hits	163
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

KI13A_HUMAN
NC score	0.009366 (rank : 2497)	θ value	1.81305 (rank : 1950)
Query Neighborhood Hits	2923	Target Neighborhood Hits	359	Shared Neighborhood Hits	176
SwissProt Accessions	Q9H1H9, Q9H1H8	Gene names	KIF13A, RBKIN
Domain Architecture
Description	Kinesin-like protein KIF13A (Kinesin-like protein RBKIN).

NUMBL_HUMAN
NC score	0.009360 (rank : 2498)	θ value	2.36792 (rank : 2087)
Query Neighborhood Hits	2923	Target Neighborhood Hits	394	Shared Neighborhood Hits	130
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

TULP4_HUMAN
NC score	0.009346 (rank : 2499)	θ value	8.99809 (rank : 2906)
Query Neighborhood Hits	2923	Target Neighborhood Hits	426	Shared Neighborhood Hits	121
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

NMI_HUMAN
NC score	0.009291 (rank : 2500)	θ value	2.36792 (rank : 2084)
Query Neighborhood Hits	2923	Target Neighborhood Hits	102	Shared Neighborhood Hits	54
SwissProt Accessions	Q13287, Q53TI8, Q9BVE5	Gene names	NMI
Domain Architecture
Description	N-myc-interactor (Nmi) (N-myc and STAT interactor).

ZN185_MOUSE
NC score	0.009261 (rank : 2501)	θ value	2.36792 (rank : 2122)
Query Neighborhood Hits	2923	Target Neighborhood Hits	89	Shared Neighborhood Hits	28
SwissProt Accessions	Q62394	Gene names	Znf185, Zfp185
Domain Architecture
Description	Zinc finger protein 185 (LIM-domain protein Zfp185) (P1-A).

ATS12_HUMAN
NC score	0.009248 (rank : 2502)	θ value	4.03905 (rank : 2253)
Query Neighborhood Hits	2923	Target Neighborhood Hits	251	Shared Neighborhood Hits	49
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

TM110_HUMAN
NC score	0.009228 (rank : 2503)	θ value	0.813845 (rank : 1754)
Query Neighborhood Hits	2923	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q86TL2	Gene names	TMEM110
Domain Architecture	No domain graphic available
Description	Transmembrane protein 110.

RL4_HUMAN
NC score	0.009188 (rank : 2504)	θ value	5.27518 (rank : 2499)
Query Neighborhood Hits	2923	Target Neighborhood Hits	13	Shared Neighborhood Hits	7
SwissProt Accessions	P36578, P39029, Q4VBR0, Q969Z9	Gene names	RPL4, RPL1
Domain Architecture
Description	60S ribosomal protein L4 (L1).

CHD6_HUMAN
NC score	0.009185 (rank : 2505)	θ value	4.03905 (rank : 2263)
Query Neighborhood Hits	2923	Target Neighborhood Hits	342	Shared Neighborhood Hits	142
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

DOCK4_HUMAN
NC score	0.009156 (rank : 2506)	θ value	8.99809 (rank : 2768)
Query Neighborhood Hits	2923	Target Neighborhood Hits	237	Shared Neighborhood Hits	99
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

EPC2_MOUSE
NC score	0.009096 (rank : 2507)	θ value	6.88961 (rank : 2595)
Query Neighborhood Hits	2923	Target Neighborhood Hits	59	Shared Neighborhood Hits	38
SwissProt Accessions	Q8C0I4, Q3URX9, Q80Y70, Q8BXC5	Gene names	Epc2
Domain Architecture	No domain graphic available
Description	Enhancer of polycomb homolog 2.

CX039_HUMAN
NC score	0.008984 (rank : 2508)	θ value	1.81305 (rank : 1924)
Query Neighborhood Hits	2923	Target Neighborhood Hits	20	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PEV8, Q8WVP6, Q96AV3	Gene names	CXorf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein CXorf39.

MPRI_HUMAN
NC score	0.008967 (rank : 2509)	θ value	4.03905 (rank : 2317)
Query Neighborhood Hits	2923	Target Neighborhood Hits	67	Shared Neighborhood Hits	21
SwissProt Accessions	P11717, Q7Z7G9, Q96PT5	Gene names	IGF2R, MPRI
Domain Architecture
Description	Cation-independent mannose-6-phosphate receptor precursor (CI Man-6-P receptor) (CI-MPR) (M6PR) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (300 kDa mannose 6-phosphate receptor) (MPR 300) (MPR300) (CD222 antigen).

DC1L2_MOUSE
NC score	0.008865 (rank : 2510)	θ value	3.0926 (rank : 2151)
Query Neighborhood Hits	2923	Target Neighborhood Hits	173	Shared Neighborhood Hits	48
SwissProt Accessions	Q6PDL0	Gene names	Dync1li2, Dncli2, Dnclic2
Domain Architecture	No domain graphic available
Description	Cytoplasmic dynein 1 light intermediate chain 2 (Dynein light intermediate chain 2, cytosolic).

NAT6_MOUSE
NC score	0.008859 (rank : 2511)	θ value	8.99809 (rank : 2842)
Query Neighborhood Hits	2923	Target Neighborhood Hits	36	Shared Neighborhood Hits	18
SwissProt Accessions	Q9R123, Q8QZY5, Q8R014, Q9ERM0	Gene names	Nat6, Fus2
Domain Architecture
Description	N-acetyltransferase 6 (EC 2.3.1.-) (Fus-2 protein) (Fusion 2 protein).

TERF2_MOUSE
NC score	0.008800 (rank : 2512)	θ value	8.99809 (rank : 2898)
Query Neighborhood Hits	2923	Target Neighborhood Hits	128	Shared Neighborhood Hits	57
SwissProt Accessions	O35144	Gene names	Terf2, Trf2
Domain Architecture
Description	Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein).

MYBB_HUMAN
NC score	0.008777 (rank : 2513)	θ value	1.06291 (rank : 1796)
Query Neighborhood Hits	2923	Target Neighborhood Hits	78	Shared Neighborhood Hits	36
SwissProt Accessions	P10244	Gene names	MYBL2, BMYB
Domain Architecture
Description	Myb-related protein B (B-Myb).

S19BP_HUMAN
NC score	0.008748 (rank : 2514)	θ value	2.36792 (rank : 2100)
Query Neighborhood Hits	2923	Target Neighborhood Hits	13	Shared Neighborhood Hits	5
SwissProt Accessions	Q86WX3, Q5JZA1	Gene names	RPS19BP1
Domain Architecture	No domain graphic available
Description	40S ribosomal protein S19-binding protein 1 (RPS19-binding protein 1) (S19BP).

ARHG1_MOUSE
NC score	0.008684 (rank : 2515)	θ value	1.81305 (rank : 1910)
Query Neighborhood Hits	2923	Target Neighborhood Hits	266	Shared Neighborhood Hits	94
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

SI1L3_HUMAN
NC score	0.008652 (rank : 2516)	θ value	4.03905 (rank : 2355)
Query Neighborhood Hits	2923	Target Neighborhood Hits	305	Shared Neighborhood Hits	120
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

DYN1_MOUSE
NC score	0.008651 (rank : 2517)	θ value	3.0926 (rank : 2158)
Query Neighborhood Hits	2923	Target Neighborhood Hits	168	Shared Neighborhood Hits	72
SwissProt Accessions	P39053, Q61358, Q61359, Q61360, Q8JZZ4, Q9CSY7, Q9QXX1	Gene names	Dnm1, Dnm
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

DACH1_MOUSE
NC score	0.008638 (rank : 2518)	θ value	4.03905 (rank : 2270)
Query Neighborhood Hits	2923	Target Neighborhood Hits	228	Shared Neighborhood Hits	101
SwissProt Accessions	Q9QYB2, O88716, Q8BPQ0, Q8C8D7, Q9QY47, Q9R218, Q9Z0Y5	Gene names	Dach1, Dach
Domain Architecture
Description	Dachshund homolog 1 (Dach1).

SPAG7_HUMAN
NC score	0.008637 (rank : 2519)	θ value	5.27518 (rank : 2518)
Query Neighborhood Hits	2923	Target Neighborhood Hits	25	Shared Neighborhood Hits	17
SwissProt Accessions	O75391, Q96EU5	Gene names	SPAG7
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 7.

TAF6L_MOUSE
NC score	0.008597 (rank : 2520)	θ value	3.0926 (rank : 2227)
Query Neighborhood Hits	2923	Target Neighborhood Hits	146	Shared Neighborhood Hits	44
SwissProt Accessions	Q8R2K4, Q8C5T2	Gene names	Taf6l, Paf65a
Domain Architecture
Description	TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (PCAF-associated factor 65 alpha) (PAF65- alpha).

CALX_MOUSE
NC score	0.008569 (rank : 2521)	θ value	1.38821 (rank : 1824)
Query Neighborhood Hits	2923	Target Neighborhood Hits	76	Shared Neighborhood Hits	28
SwissProt Accessions	P35564	Gene names	Canx
Domain Architecture
Description	Calnexin precursor.

SPT6H_HUMAN
NC score	0.008556 (rank : 2522)	θ value	8.99809 (rank : 2888)
Query Neighborhood Hits	2923	Target Neighborhood Hits	104	Shared Neighborhood Hits	40
SwissProt Accessions	Q7KZ85, Q15737, Q6GMQ4, Q7KYW9, Q7LDK4, Q8N526, Q92775, Q96AH3, Q9BTH9, Q9BTI2	Gene names	SUPT6H, KIAA0162, SPT6H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT6 (hSPT6) (Tat-cotransactivator 2 protein) (Tat-CT2 protein).

SIA7A_MOUSE
NC score	0.008506 (rank : 2523)	θ value	0.62314 (rank : 1693)
Query Neighborhood Hits	2923	Target Neighborhood Hits	203	Shared Neighborhood Hits	79
SwissProt Accessions	Q9QZ39, Q9JJP5	Gene names	St6galnac1, Siat7a
Domain Architecture
Description	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (EC 2.4.99.3) (GalNAc alpha-2,6-sialyltransferase I) (ST6GalNAc I) (Sialyltransferase 7A).

RBM6_HUMAN
NC score	0.008503 (rank : 2524)	θ value	5.27518 (rank : 2496)
Query Neighborhood Hits	2923	Target Neighborhood Hits	221	Shared Neighborhood Hits	72
SwissProt Accessions	P78332, O60549, O75524	Gene names	RBM6, DEF3
Domain Architecture
Description	RNA-binding protein 6 (RNA-binding motif protein 6) (RNA-binding protein DEF-3) (Lung cancer antigen NY-LU-12) (Protein G16).

MYBB_MOUSE
NC score	0.008382 (rank : 2525)	θ value	1.81305 (rank : 1961)
Query Neighborhood Hits	2923	Target Neighborhood Hits	73	Shared Neighborhood Hits	35
SwissProt Accessions	P48972	Gene names	Mybl2, Bmyb
Domain Architecture
Description	Myb-related protein B (B-Myb).

SMN_HUMAN
NC score	0.008349 (rank : 2526)	θ value	3.0926 (rank : 2224)
Query Neighborhood Hits	2923	Target Neighborhood Hits	39	Shared Neighborhood Hits	14
SwissProt Accessions	Q16637, Q13119, Q96J51	Gene names	SMN1, SMN, SMNT
Domain Architecture
Description	Survival motor neuron protein (Component of gems 1) (Gemin-1).

CHD9_HUMAN
NC score	0.008344 (rank : 2527)	θ value	0.47712 (rank : 1595)
Query Neighborhood Hits	2923	Target Neighborhood Hits	343	Shared Neighborhood Hits	130
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

EHMT2_MOUSE
NC score	0.008293 (rank : 2528)	θ value	2.36792 (rank : 2043)
Query Neighborhood Hits	2923	Target Neighborhood Hits	750	Shared Neighborhood Hits	183
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

CT072_HUMAN
NC score	0.008277 (rank : 2529)	θ value	1.06291 (rank : 1774)
Query Neighborhood Hits	2923	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BQP7, Q96SW3	Gene names	C20orf72
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf72.

ATF6B_HUMAN
NC score	0.008257 (rank : 2530)	θ value	1.06291 (rank : 1766)
Query Neighborhood Hits	2923	Target Neighborhood Hits	122	Shared Neighborhood Hits	49
SwissProt Accessions	Q99941, Q13269, Q14343, Q14345, Q99635, Q99637, Q9H3V9, Q9H3W1, Q9NPL0	Gene names	CREBL1, G13
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp) (Protein G13).

CLMN_HUMAN
NC score	0.008147 (rank : 2531)	θ value	0.813845 (rank : 1713)
Query Neighborhood Hits	2923	Target Neighborhood Hits	205	Shared Neighborhood Hits	72
SwissProt Accessions	Q96JQ2, Q9H713, Q9HA23, Q9HA57, Q9UFP4, Q9ULN2	Gene names	CLMN, KIAA1188
Domain Architecture
Description	Calmin.

UB7I1_MOUSE
NC score	0.008138 (rank : 2532)	θ value	2.36792 (rank : 2115)
Query Neighborhood Hits	2923	Target Neighborhood Hits	206	Shared Neighborhood Hits	58
SwissProt Accessions	P58283, Q3U493, Q3UE56, Q3UGM3, Q68FN0, Q6P1H8, Q6PWY5, Q8BN27, Q8C1U3	Gene names	Ubce7ip1, Triad3, Uip83, Zin
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (UbcM4-interacting protein 83) (Triad domain- containing protein 3).

APBA2_HUMAN
NC score	0.008129 (rank : 2533)	θ value	0.47712 (rank : 1585)
Query Neighborhood Hits	2923	Target Neighborhood Hits	220	Shared Neighborhood Hits	50
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

FA48A_HUMAN
NC score	0.008101 (rank : 2534)	θ value	6.88961 (rank : 2597)
Query Neighborhood Hits	2923	Target Neighborhood Hits	51	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NEM7, Q71RF3, Q9Y6A6	Gene names	FAM48A
Domain Architecture	No domain graphic available
Description	Protein FAM48A (p38-interacting protein) (p38IP).

2ACA_HUMAN
NC score	0.008100 (rank : 2535)	θ value	6.88961 (rank : 2541)
Query Neighborhood Hits	2923	Target Neighborhood Hits	100	Shared Neighborhood Hits	60
SwissProt Accessions	Q06190, Q06189, Q9NPQ5	Gene names	PPP2R3A, PPP2R3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 72/130 kDa regulatory subunit B (PP2A, subunit B, B''-PR72/PR130) (PP2A, subunit B, B72/B130 isoforms) (PP2A, subunit B, PR72/PR130 isoforms) (PP2A, subunit B, R3 isoform).

EPC2_HUMAN
NC score	0.008038 (rank : 2536)	θ value	6.88961 (rank : 2594)
Query Neighborhood Hits	2923	Target Neighborhood Hits	58	Shared Neighborhood Hits	34
SwissProt Accessions	Q52LR7, Q7L9J1, Q96RR7, Q9NUT8, Q9NVR1, Q9UFM9	Gene names	EPC2
Domain Architecture	No domain graphic available
Description	Enhancer of polycomb homolog 2.

CNGB3_HUMAN
NC score	0.008036 (rank : 2537)	θ value	8.99809 (rank : 2755)
Query Neighborhood Hits	2923	Target Neighborhood Hits	206	Shared Neighborhood Hits	85
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

TERF2_HUMAN
NC score	0.008033 (rank : 2538)	θ value	6.88961 (rank : 2698)
Query Neighborhood Hits	2923	Target Neighborhood Hits	102	Shared Neighborhood Hits	51
SwissProt Accessions	Q15554	Gene names	TERF2, TRF2
Domain Architecture
Description	Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein).

SEM3E_MOUSE
NC score	0.008017 (rank : 2539)	θ value	2.36792 (rank : 2102)
Query Neighborhood Hits	2923	Target Neighborhood Hits	76	Shared Neighborhood Hits	29
SwissProt Accessions	P70275, O09078, O09079	Gene names	Sema3e, Semah, Semh
Domain Architecture
Description	Semaphorin-3E precursor (Semaphorin H) (Sema H).

ANF_HUMAN
NC score	0.008016 (rank : 2540)	θ value	2.36792 (rank : 2012)
Query Neighborhood Hits	2923	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	P01160, Q13766	Gene names	NPPA, PND
Domain Architecture
Description	Atrial natriuretic factor precursor (ANF) (Atrial natriuretic peptide) (ANP) (Prepronatriodilatin) (CDD-ANF) [Contains: Cardiodilatin-related peptide (CDP)].

LYRM3_HUMAN
NC score	0.007983 (rank : 2541)	θ value	3.0926 (rank : 2189)
Query Neighborhood Hits	2923	Target Neighborhood Hits	3	Shared Neighborhood Hits	2
SwissProt Accessions	Q5U5X0, Q86Y68	Gene names	LYRM3, C5orf31
Domain Architecture	No domain graphic available
Description	LYR motif-containing protein 3.

CCNK_HUMAN
NC score	0.007924 (rank : 2542)	θ value	4.03905 (rank : 2261)
Query Neighborhood Hits	2923	Target Neighborhood Hits	101	Shared Neighborhood Hits	58
SwissProt Accessions	O75909, Q96B63, Q9NNY9	Gene names	CCNK, CPR4
Domain Architecture
Description	Cyclin-K.

SMG7_MOUSE
NC score	0.007913 (rank : 2543)	θ value	8.99809 (rank : 2882)
Query Neighborhood Hits	2923	Target Neighborhood Hits	113	Shared Neighborhood Hits	54
SwissProt Accessions	Q5RJH6, Q63ZW5, Q6ZQF3	Gene names	Smg7, Est1c, Kiaa0250
Domain Architecture	No domain graphic available
Description	Protein SMG7 (SMG-7 homolog) (EST1-like protein C).

DYH5_HUMAN
NC score	0.007813 (rank : 2544)	θ value	8.99809 (rank : 2772)
Query Neighborhood Hits	2923	Target Neighborhood Hits	323	Shared Neighborhood Hits	158
SwissProt Accessions	Q8TE73, Q92860, Q96L74, Q9H5S7, Q9HCG9	Gene names	DNAH5, DNAHC5, KIAA1603
Domain Architecture	No domain graphic available
Description	Ciliary dynein heavy chain 5 (Axonemal beta dynein heavy chain 5) (HL1).

NOG2_MOUSE
NC score	0.007808 (rank : 2545)	θ value	3.0926 (rank : 2199)
Query Neighborhood Hits	2923	Target Neighborhood Hits	71	Shared Neighborhood Hits	37
SwissProt Accessions	Q99LH1, Q8BIF8	Gene names	Gnl2
Domain Architecture	No domain graphic available
Description	Nucleolar GTP-binding protein 2.

COG8_MOUSE
NC score	0.007800 (rank : 2546)	θ value	2.36792 (rank : 2034)
Query Neighborhood Hits	2923	Target Neighborhood Hits	147	Shared Neighborhood Hits	50
SwissProt Accessions	Q9JJA2	Gene names	Cog8
Domain Architecture
Description	Conserved oligomeric Golgi complex component 8.

TF3C4_MOUSE
NC score	0.007766 (rank : 2547)	θ value	0.813845 (rank : 1753)
Query Neighborhood Hits	2923	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BMQ2, Q8BKZ4	Gene names	Gtf3c4
Domain Architecture	No domain graphic available
Description	General transcription factor 3C polypeptide 4 (EC 2.3.1.48) (Transcription factor IIIC subunit delta) (TF3C-delta) (TFIIIC 90 kDa subunit) (TFIIIC 90).

CALR_HUMAN
NC score	0.007729 (rank : 2548)	θ value	2.36792 (rank : 2019)
Query Neighborhood Hits	2923	Target Neighborhood Hits	85	Shared Neighborhood Hits	37
SwissProt Accessions	P27797	Gene names	CALR, CRTC
Domain Architecture
Description	Calreticulin precursor (CRP55) (Calregulin) (HACBP) (ERp60) (grp60).

UBP42_HUMAN
NC score	0.007718 (rank : 2549)	θ value	8.99809 (rank : 2911)
Query Neighborhood Hits	2923	Target Neighborhood Hits	445	Shared Neighborhood Hits	149
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

BAP1_HUMAN
NC score	0.007624 (rank : 2550)	θ value	6.88961 (rank : 2550)
Query Neighborhood Hits	2923	Target Neighborhood Hits	106	Shared Neighborhood Hits	44
SwissProt Accessions	Q92560, Q6LEM0, Q7Z5E8	Gene names	BAP1, KIAA0272
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1- associated protein 1) (Cerebral protein 6).

YAP1_HUMAN
NC score	0.007609 (rank : 2551)	θ value	8.99809 (rank : 2916)
Query Neighborhood Hits	2923	Target Neighborhood Hits	173	Shared Neighborhood Hits	72
SwissProt Accessions	P46937	Gene names	YAP1, YAP65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

RECQ5_HUMAN
NC score	0.007565 (rank : 2552)	θ value	1.81305 (rank : 1973)
Query Neighborhood Hits	2923	Target Neighborhood Hits	390	Shared Neighborhood Hits	134
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

MYST4_MOUSE
NC score	0.007541 (rank : 2553)	θ value	3.0926 (rank : 2195)
Query Neighborhood Hits	2923	Target Neighborhood Hits	416	Shared Neighborhood Hits	160
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

TXD11_MOUSE
NC score	0.007527 (rank : 2554)	θ value	1.81305 (rank : 2004)
Query Neighborhood Hits	2923	Target Neighborhood Hits	81	Shared Neighborhood Hits	27
SwissProt Accessions	Q8K2W3, Q8BMR8, Q8VCK9	Gene names	Txndc11
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 11.

GGA1_MOUSE
NC score	0.007484 (rank : 2555)	θ value	8.99809 (rank : 2787)
Query Neighborhood Hits	2923	Target Neighborhood Hits	128	Shared Neighborhood Hits	71
SwissProt Accessions	Q8R0H9, Q3U2N1	Gene names	Gga1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

PDZD1_MOUSE
NC score	0.007384 (rank : 2556)	θ value	2.36792 (rank : 2090)
Query Neighborhood Hits	2923	Target Neighborhood Hits	191	Shared Neighborhood Hits	43
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

LIMA1_MOUSE
NC score	0.007295 (rank : 2557)	θ value	4.03905 (rank : 2307)
Query Neighborhood Hits	2923	Target Neighborhood Hits	298	Shared Neighborhood Hits	88
SwissProt Accessions	Q9ERG0, Q9ERG1	Gene names	Lima1, D15Ertd366e, Eplin
Domain Architecture
Description	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm) (mEPLIN).

TERT_MOUSE
NC score	0.007243 (rank : 2558)	θ value	2.36792 (rank : 2109)
Query Neighborhood Hits	2923	Target Neighborhood Hits	50	Shared Neighborhood Hits	27
SwissProt Accessions	O70372, O35432, Q9JK99	Gene names	Tert
Domain Architecture	No domain graphic available
Description	Telomerase reverse transcriptase (EC 2.7.7.49) (Telomerase catalytic subunit).

TOPB1_MOUSE
NC score	0.007199 (rank : 2559)	θ value	4.03905 (rank : 2363)
Query Neighborhood Hits	2923	Target Neighborhood Hits	89	Shared Neighborhood Hits	38
SwissProt Accessions	Q6ZQF0, Q6P6P0, Q80Y33, Q8BUI0, Q8BUK1, Q8R348, Q91VX3, Q922X8	Gene names	Topbp1, Kiaa0259
Domain Architecture	No domain graphic available
Description	DNA topoisomerase II-binding protein 1 (DNA topoisomerase IIbeta- binding protein 1) (TopBP1).

LRBA_HUMAN
NC score	0.007195 (rank : 2560)	θ value	0.0330416 (rank : 1268)
Query Neighborhood Hits	2923	Target Neighborhood Hits	196	Shared Neighborhood Hits	41
SwissProt Accessions	P50851, Q9H2U3, Q9H2U4	Gene names	LRBA, BGL, CDC4L, LBA
Domain Architecture
Description	Lipopolysaccharide-responsive and beige-like anchor protein (CDC4-like protein) (Beige-like protein).

PALB2_HUMAN
NC score	0.007194 (rank : 2561)	θ value	8.99809 (rank : 2849)
Query Neighborhood Hits	2923	Target Neighborhood Hits	117	Shared Neighborhood Hits	55
SwissProt Accessions	Q86YC2, Q8N7Y6, Q8ND31, Q9H6W1	Gene names	PALB2
Domain Architecture	No domain graphic available
Description	Partner and localizer of BRCA2.

VPS53_MOUSE
NC score	0.007193 (rank : 2562)	θ value	6.88961 (rank : 2708)
Query Neighborhood Hits	2923	Target Neighborhood Hits	102	Shared Neighborhood Hits	60
SwissProt Accessions	Q8CCB4, Q8C7U0, Q8CIA1, Q9CX82, Q9D6T7	Gene names	Vps53
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 53.

CYH3_HUMAN
NC score	0.007191 (rank : 2563)	θ value	1.38821 (rank : 1833)
Query Neighborhood Hits	2923	Target Neighborhood Hits	137	Shared Neighborhood Hits	41
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

MGP_MOUSE
NC score	0.007174 (rank : 2564)	θ value	5.27518 (rank : 2464)
Query Neighborhood Hits	2923	Target Neighborhood Hits	3	Shared Neighborhood Hits	3
SwissProt Accessions	P19788, Q8JZW0	Gene names	Mgp, Mglap
Domain Architecture
Description	Matrix Gla-protein precursor (MGP).

MYSM1_MOUSE
NC score	0.007166 (rank : 2565)	θ value	8.99809 (rank : 2839)
Query Neighborhood Hits	2923	Target Neighborhood Hits	134	Shared Neighborhood Hits	59
SwissProt Accessions	Q69Z66, Q3TPV7, Q8BRP5, Q8C4N1	Gene names	Mysm1, Kiaa1915
Domain Architecture	No domain graphic available
Description	Protein MYSM1 (Myb-like, SWIRM and MPN domain-containing protein 1).

CBL_HUMAN
NC score	0.007162 (rank : 2566)	θ value	0.47712 (rank : 1591)
Query Neighborhood Hits	2923	Target Neighborhood Hits	353	Shared Neighborhood Hits	85
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

EGF_HUMAN
NC score	0.007128 (rank : 2567)	θ value	4.03905 (rank : 2276)
Query Neighborhood Hits	2923	Target Neighborhood Hits	343	Shared Neighborhood Hits	67
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

IRBP_HUMAN
NC score	0.007123 (rank : 2568)	θ value	0.62314 (rank : 1673)
Query Neighborhood Hits	2923	Target Neighborhood Hits	17	Shared Neighborhood Hits	7
SwissProt Accessions	P10745	Gene names	RBP3
Domain Architecture
Description	Interphotoreceptor retinoid-binding protein precursor (IRBP) (Interstitial retinol-binding protein).

PHF22_HUMAN
NC score	0.007105 (rank : 2569)	θ value	8.99809 (rank : 2854)
Query Neighborhood Hits	2923	Target Neighborhood Hits	121	Shared Neighborhood Hits	46
SwissProt Accessions	Q96CB8, Q9HD71	Gene names	INTS12, PHF22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

CHD2_HUMAN
NC score	0.007105 (rank : 2570)	θ value	6.88961 (rank : 2566)
Query Neighborhood Hits	2923	Target Neighborhood Hits	360	Shared Neighborhood Hits	144
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

MYSM1_HUMAN
NC score	0.007003 (rank : 2571)	θ value	1.38821 (rank : 1867)
Query Neighborhood Hits	2923	Target Neighborhood Hits	73	Shared Neighborhood Hits	30
SwissProt Accessions	Q5VVJ2, Q7Z3G8, Q96PX3	Gene names	MYSM1, KIAA1915
Domain Architecture	No domain graphic available
Description	Protein MYSM1 (Myb-like, SWIRM and MPN domain-containing protein 1).

MNDA_HUMAN
NC score	0.006999 (rank : 2572)	θ value	5.27518 (rank : 2466)
Query Neighborhood Hits	2923	Target Neighborhood Hits	76	Shared Neighborhood Hits	47
SwissProt Accessions	P41218	Gene names	MNDA
Domain Architecture
Description	Myeloid cell nuclear differentiation antigen.

ZSWM3_HUMAN
NC score	0.006999 (rank : 2573)	θ value	0.47712 (rank : 1646)
Query Neighborhood Hits	2923	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q96MP5, Q9BR13	Gene names	ZSWIM3, C20orf164
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 3.

PTCD1_HUMAN
NC score	0.006981 (rank : 2574)	θ value	4.03905 (rank : 2336)
Query Neighborhood Hits	2923	Target Neighborhood Hits	52	Shared Neighborhood Hits	28
SwissProt Accessions	O75127, Q66K60, Q9UDV2	Gene names	PTCD1, KIAA0632
Domain Architecture	No domain graphic available
Description	Pentatricopeptide repeat protein 1.

SEM3E_HUMAN
NC score	0.006904 (rank : 2575)	θ value	1.38821 (rank : 1881)
Query Neighborhood Hits	2923	Target Neighborhood Hits	73	Shared Neighborhood Hits	26
SwissProt Accessions	O15041, Q75M94, Q75M97	Gene names	SEMA3E, KIAA0331
Domain Architecture	No domain graphic available
Description	Semaphorin-3E precursor.

CF142_HUMAN
NC score	0.006866 (rank : 2576)	θ value	3.0926 (rank : 2146)
Query Neighborhood Hits	2923	Target Neighborhood Hits	25	Shared Neighborhood Hits	11
SwissProt Accessions	Q5VWP3, Q96H08, Q96NF7	Gene names	C6orf142
Domain Architecture	No domain graphic available
Description	Protein C6orf142.

RN168_HUMAN
NC score	0.006848 (rank : 2577)	θ value	1.81305 (rank : 1974)
Query Neighborhood Hits	2923	Target Neighborhood Hits	370	Shared Neighborhood Hits	103
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

UCRI_MOUSE
NC score	0.006804 (rank : 2578)	θ value	2.36792 (rank : 2119)
Query Neighborhood Hits	2923	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CR68	Gene names	Uqcrfs1
Domain Architecture	No domain graphic available
Description	Ubiquinol-cytochrome c reductase iron-sulfur subunit, mitochondrial precursor (EC 1.10.2.2) (Rieske iron-sulfur protein) (RISP).

JHD2A_HUMAN
NC score	0.006794 (rank : 2579)	θ value	1.38821 (rank : 1854)
Query Neighborhood Hits	2923	Target Neighborhood Hits	118	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y4C1, Q53S72, Q68D47, Q68UT9, Q6N050, Q8IY08	Gene names	JMJD1A, JHDM2A, JMJD1, KIAA0742
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2A (EC 1.14.11.-) (Jumonji domain-containing protein 1A).

DDEF2_HUMAN
NC score	0.006718 (rank : 2580)	θ value	2.36792 (rank : 2038)
Query Neighborhood Hits	2923	Target Neighborhood Hits	599	Shared Neighborhood Hits	176
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

NUP98_HUMAN
NC score	0.006688 (rank : 2581)	θ value	6.88961 (rank : 2663)
Query Neighborhood Hits	2923	Target Neighborhood Hits	81	Shared Neighborhood Hits	29
SwissProt Accessions	P52948, Q8IUT2, Q8WYB0, Q96E54, Q9H3Q4, Q9NT02, Q9UF57, Q9UHX0, Q9Y6J4, Q9Y6J5	Gene names	NUP98
Domain Architecture
Description	Nuclear pore complex protein Nup98-Nup96 precursor [Contains: Nuclear pore complex protein Nup98 (Nucleoporin Nup98) (98 kDa nucleoporin); Nuclear pore complex protein Nup96 (Nucleoporin Nup96) (96 kDa nucleoporin)].

DPPA4_MOUSE
NC score	0.006683 (rank : 2582)	θ value	1.81305 (rank : 1929)
Query Neighborhood Hits	2923	Target Neighborhood Hits	10	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CCG4, Q6P228, Q810Y6	Gene names	Dppa4
Domain Architecture	No domain graphic available
Description	Developmental pluripotency-associated protein 4.

CND3_HUMAN
NC score	0.006661 (rank : 2583)	θ value	5.27518 (rank : 2401)
Query Neighborhood Hits	2923	Target Neighborhood Hits	74	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BPX3, Q96SV9, Q9BUR3, Q9BVY1, Q9H914, Q9H9Z6, Q9HBI9	Gene names	NCAPG, CAPG, NYMEL3
Domain Architecture
Description	Condensin complex subunit 3 (Non-SMC condensin I complex subunit G) (Chromosome-associated protein G) (Condensin subunit CAP-G) (hCAP-G) (XCAP-G homolog) (Antigen NY-MEL-3).

STAT1_MOUSE
NC score	0.006645 (rank : 2584)	θ value	6.88961 (rank : 2695)
Query Neighborhood Hits	2923	Target Neighborhood Hits	151	Shared Neighborhood Hits	78
SwissProt Accessions	P42225	Gene names	Stat1
Domain Architecture
Description	Signal transducer and activator of transcription 1.

ANTR2_MOUSE
NC score	0.006633 (rank : 2585)	θ value	8.99809 (rank : 2730)
Query Neighborhood Hits	2923	Target Neighborhood Hits	26	Shared Neighborhood Hits	11
SwissProt Accessions	Q6DFX2, Q99L17	Gene names	Antxr2
Domain Architecture	No domain graphic available
Description	Anthrax toxin receptor 2 precursor.

MBIP1_HUMAN
NC score	0.006613 (rank : 2586)	θ value	5.27518 (rank : 2461)
Query Neighborhood Hits	2923	Target Neighborhood Hits	27	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NS73, Q86TZ2, Q96AS5, Q9BS93, Q9NZE1	Gene names	MBIP
Domain Architecture	No domain graphic available
Description	MAP3K12-binding inhibitory protein 1 (MAPK upstream kinase-binding inhibitory protein) (MUK-binding inhibitory protein).

CP007_HUMAN
NC score	0.006605 (rank : 2587)	θ value	8.99809 (rank : 2757)
Query Neighborhood Hits	2923	Target Neighborhood Hits	85	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y2B5	Gene names	C16orf7, ATPBL
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf7 (Protein ATP-BL).

SGOL1_MOUSE
NC score	0.006584 (rank : 2588)	θ value	6.88961 (rank : 2691)
Query Neighborhood Hits	2923	Target Neighborhood Hits	65	Shared Neighborhood Hits	30
SwissProt Accessions	Q9CXH7, Q3U4K4, Q588H1, Q8BKW2	Gene names	Sgol1, Sgo1
Domain Architecture	No domain graphic available
Description	Shugoshin-like 1.

COG3_HUMAN
NC score	0.006515 (rank : 2589)	θ value	6.88961 (rank : 2573)
Query Neighborhood Hits	2923	Target Neighborhood Hits	56	Shared Neighborhood Hits	24
SwissProt Accessions	Q96JB2, Q5VT70, Q8IXX4, Q9BZ92	Gene names	COG3, SEC34
Domain Architecture
Description	Conserved oligomeric Golgi complex component 3 (Vesicle docking protein SEC34 homolog) (p94).

AIM2_HUMAN
NC score	0.006501 (rank : 2590)	θ value	0.47712 (rank : 1584)
Query Neighborhood Hits	2923	Target Neighborhood Hits	34	Shared Neighborhood Hits	10
SwissProt Accessions	O14862	Gene names	AIM2
Domain Architecture
Description	Interferon-inducible protein AIM2 (Absent in melanoma 2).

RS3_HUMAN
NC score	0.006405 (rank : 2591)	θ value	4.03905 (rank : 2347)
Query Neighborhood Hits	2923	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	P23396, Q498B5, Q8NI95	Gene names	RPS3
Domain Architecture
Description	40S ribosomal protein S3.

RS3_MOUSE
NC score	0.006386 (rank : 2592)	θ value	4.03905 (rank : 2348)
Query Neighborhood Hits	2923	Target Neighborhood Hits	13	Shared Neighborhood Hits	7
SwissProt Accessions	P62908, P17073, P47933	Gene names	Rps3
Domain Architecture	No domain graphic available
Description	40S ribosomal protein S3.

LRC41_HUMAN
NC score	0.006325 (rank : 2593)	θ value	8.99809 (rank : 2825)
Query Neighborhood Hits	2923	Target Neighborhood Hits	51	Shared Neighborhood Hits	18
SwissProt Accessions	Q15345, Q71RA8, Q9BSM0	Gene names	LRRC41, MUF1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 41 (Protein Muf1).

JHD2A_MOUSE
NC score	0.006293 (rank : 2594)	θ value	2.36792 (rank : 2065)
Query Neighborhood Hits	2923	Target Neighborhood Hits	123	Shared Neighborhood Hits	53
SwissProt Accessions	Q6PCM1, Q2MJQ6, Q3TKW8, Q3UML3, Q6ZQ57, Q8K2J6, Q8K2K4, Q8R350	Gene names	Jmjd1a, Jhdm2a, Kiaa0742
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2A (EC 1.14.11.-) (Jumonji domain-containing protein 1A).

ESPL1_HUMAN
NC score	0.006258 (rank : 2595)	θ value	1.38821 (rank : 1844)
Query Neighborhood Hits	2923	Target Neighborhood Hits	95	Shared Neighborhood Hits	35
SwissProt Accessions	Q14674	Gene names	ESPL1, ESP1, KIAA0165
Domain Architecture
Description	Separin (EC 3.4.22.49) (Separase) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein).

GASP1_MOUSE
NC score	0.006221 (rank : 2596)	θ value	5.27518 (rank : 2426)
Query Neighborhood Hits	2923	Target Neighborhood Hits	169	Shared Neighborhood Hits	69
SwissProt Accessions	Q5U4C1, Q8BKR8, Q8BUN4, Q8BYK9, Q8CHF4, Q8R095	Gene names	Gprasp1, Kiaa0443
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor-associated sorting protein 1 (GASP-1).

LV5A_HUMAN
NC score	0.006200 (rank : 2597)	θ value	0.0961366 (rank : 1370)
Query Neighborhood Hits	2923	Target Neighborhood Hits	220	Shared Neighborhood Hits	80
SwissProt Accessions	P01719	Gene names
Domain Architecture	No domain graphic available
Description	Ig lambda chain V-V region DEL.

MGP_HUMAN
NC score	0.006151 (rank : 2598)	θ value	6.88961 (rank : 2649)
Query Neighborhood Hits	2923	Target Neighborhood Hits	3	Shared Neighborhood Hits	3
SwissProt Accessions	P08493	Gene names	MGP, MGLAP
Domain Architecture
Description	Matrix Gla-protein precursor (MGP).

VPS25_HUMAN
NC score	0.006145 (rank : 2599)	θ value	3.0926 (rank : 2239)
Query Neighborhood Hits	2923	Target Neighborhood Hits	3	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BRG1	Gene names	VPS25, DERP9, EAP20
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 25 (hVps25) (ELL- associated protein of 20 kDa) (Dermal papilla-derived protein 9).

TCGAP_HUMAN
NC score	0.006085 (rank : 2600)	θ value	1.81305 (rank : 1993)
Query Neighborhood Hits	2923	Target Neighborhood Hits	872	Shared Neighborhood Hits	230
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

GDE5_MOUSE
NC score	0.006061 (rank : 2601)	θ value	0.813845 (rank : 1722)
Query Neighborhood Hits	2923	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C0L9, Q3TLV6, Q80TD5, Q8BKJ7, Q8BKW7, Q8CFW2, Q9D759	Gene names	Gde5, Kiaa1434, Prei4
Domain Architecture	No domain graphic available
Description	Putative glycerophosphodiester phosphodiesterase 5 (EC 3.1.-.-) (Preimplantation protein 4).

DLG1_MOUSE
NC score	0.006052 (rank : 2602)	θ value	4.03905 (rank : 2272)
Query Neighborhood Hits	2923	Target Neighborhood Hits	285	Shared Neighborhood Hits	65
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

SRR_MOUSE
NC score	0.006041 (rank : 2603)	θ value	1.81305 (rank : 1987)
Query Neighborhood Hits	2923	Target Neighborhood Hits	11	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QZX7	Gene names	Srr
Domain Architecture
Description	Serine racemase (EC 5.1.1.-).

CHD8_HUMAN
NC score	0.006007 (rank : 2604)	θ value	4.03905 (rank : 2264)
Query Neighborhood Hits	2923	Target Neighborhood Hits	235	Shared Neighborhood Hits	94
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

APBA2_MOUSE
NC score	0.005843 (rank : 2605)	θ value	6.88961 (rank : 2547)
Query Neighborhood Hits	2923	Target Neighborhood Hits	219	Shared Neighborhood Hits	50
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

CCNL1_MOUSE
NC score	0.005817 (rank : 2606)	θ value	1.81305 (rank : 1917)
Query Neighborhood Hits	2923	Target Neighborhood Hits	71	Shared Neighborhood Hits	29
SwissProt Accessions	Q52KE7, Q8BQ75, Q8R5H9, Q922K0, Q9CSZ3, Q9WV44	Gene names	Ccnl1, Ania6a, Ccn1
Domain Architecture	No domain graphic available
Description	Cyclin-L1 (Cyclin-L) (Cyclin Ania-6a).

4ET_MOUSE
NC score	0.005728 (rank : 2607)	θ value	6.88961 (rank : 2542)
Query Neighborhood Hits	2923	Target Neighborhood Hits	103	Shared Neighborhood Hits	42
SwissProt Accessions	Q9EST3, Q9CSS3	Gene names	Eif4enif1, Clast4
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4E transporter (eIF4E transporter) (4E-T) (Eukaryotic translation initiation factor 4E nuclear import factor 1).

TRUB1_MOUSE
NC score	0.005679 (rank : 2608)	θ value	2.36792 (rank : 2113)
Query Neighborhood Hits	2923	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C0D0, Q5EBH7, Q9D331	Gene names	Trub1
Domain Architecture	No domain graphic available
Description	Probable tRNA pseudouridine synthase 1 (EC 5.4.99.-).

CASZ1_HUMAN
NC score	0.005514 (rank : 2609)	θ value	0.0148317 (rank : 1212)
Query Neighborhood Hits	2923	Target Neighborhood Hits	473	Shared Neighborhood Hits	68
SwissProt Accessions	Q86V15, Q5T9S1, Q8WX49, Q8WX50, Q9BT16, Q9NXC6	Gene names	CASZ1, CST, ZNF693
Domain Architecture	No domain graphic available
Description	Castor homolog 1 zinc finger protein (Castor-related protein) (Zinc finger protein 693).

RT15_HUMAN
NC score	0.005485 (rank : 2610)	θ value	5.27518 (rank : 2502)
Query Neighborhood Hits	2923	Target Neighborhood Hits	27	Shared Neighborhood Hits	14
SwissProt Accessions	P82914, Q9H2K1	Gene names	MRPS15, RPMS15
Domain Architecture
Description	28S ribosomal protein S15, mitochondrial precursor (S15mt) (MRP-S15).

GDE_HUMAN
NC score	0.005473 (rank : 2611)	θ value	5.27518 (rank : 2427)
Query Neighborhood Hits	2923	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	P35573, P78354, P78544, Q9UF08	Gene names	AGL, GDE
Domain Architecture
Description	Glycogen debranching enzyme (Glycogen debrancher) [Includes: 4-alpha- glucanotransferase (EC 2.4.1.25) (Oligo-1,4-1,4-glucantransferase); Amylo-alpha-1,6-glucosidase (EC 3.2.1.33) (Amylo-1,6-glucosidase) (Dextrin 6-alpha-D-glucosidase)].

DOK2_MOUSE
NC score	0.005465 (rank : 2612)	θ value	6.88961 (rank : 2588)
Query Neighborhood Hits	2923	Target Neighborhood Hits	244	Shared Neighborhood Hits	80
SwissProt Accessions	O70469, O70272, Q99KL1	Gene names	Dok2, Frip
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)) (Dok- related protein) (Dok-R) (IL-four receptor-interacting protein) (FRIP).

MAGD4_HUMAN
NC score	0.005464 (rank : 2613)	θ value	6.88961 (rank : 2647)
Query Neighborhood Hits	2923	Target Neighborhood Hits	338	Shared Neighborhood Hits	124
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

NP1L4_MOUSE
NC score	0.005411 (rank : 2614)	θ value	0.47712 (rank : 1621)
Query Neighborhood Hits	2923	Target Neighborhood Hits	41	Shared Neighborhood Hits	13
SwissProt Accessions	Q78ZA7, O88701	Gene names	Nap1l4
Domain Architecture	No domain graphic available
Description	Nucleosome assembly protein 1-like 4.

GIDRP_HUMAN
NC score	0.005397 (rank : 2615)	θ value	4.03905 (rank : 2283)
Query Neighborhood Hits	2923	Target Neighborhood Hits	49	Shared Neighborhood Hits	23
SwissProt Accessions	Q7Z5L2, O60598, Q5W0B4, Q5W0B5, Q86VT9, Q8N9H0	Gene names	GIDRP88, C10orf28
Domain Architecture	No domain graphic available
Description	Growth inhibition and differentiation-related protein 88 (Putative mitochondrial space protein 32.1).

CC017_HUMAN
NC score	0.005375 (rank : 2616)	θ value	6.88961 (rank : 2559)
Query Neighborhood Hits	2923	Target Neighborhood Hits	6	Shared Neighborhood Hits	6
SwissProt Accessions	Q6NW34, Q68DM6, Q9H7U0, Q9UFM4	Gene names	C3orf17
Domain Architecture	No domain graphic available
Description	Protein C3orf17.

SCG2_MOUSE
NC score	0.005343 (rank : 2617)	θ value	8.99809 (rank : 2875)
Query Neighborhood Hits	2923	Target Neighborhood Hits	74	Shared Neighborhood Hits	33
SwissProt Accessions	Q03517, Q80Y79, Q9CW80	Gene names	Scg2, Chgc, Scg-2
Domain Architecture
Description	Secretogranin-2 precursor (Secretogranin II) (SgII) (Chromogranin C) [Contains: Secretoneurin (SN)].

PRP18_HUMAN
NC score	0.005314 (rank : 2618)	θ value	6.88961 (rank : 2676)
Query Neighborhood Hits	2923	Target Neighborhood Hits	52	Shared Neighborhood Hits	25
SwissProt Accessions	Q99633, Q9BUI9	Gene names	PRPF18, HPRP18
Domain Architecture
Description	Pre-mRNA-splicing factor 18 (PRP18 homolog) (hPRP18).

JHD3C_MOUSE
NC score	0.005269 (rank : 2619)	θ value	0.365318 (rank : 1554)
Query Neighborhood Hits	2923	Target Neighborhood Hits	84	Shared Neighborhood Hits	28
SwissProt Accessions	Q8VCD7, Q3UNP7, Q69ZZ5, Q8BUY6, Q8BWA1	Gene names	Jmjd2c, Jhdm3c, Kiaa0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C).

DPOLA_MOUSE
NC score	0.005263 (rank : 2620)	θ value	2.36792 (rank : 2042)
Query Neighborhood Hits	2923	Target Neighborhood Hits	56	Shared Neighborhood Hits	22
SwissProt Accessions	P33609	Gene names	Pola1, Pola
Domain Architecture
Description	DNA polymerase alpha catalytic subunit (EC 2.7.7.7).

IFT20_HUMAN
NC score	0.005259 (rank : 2621)	θ value	8.99809 (rank : 2800)
Query Neighborhood Hits	2923	Target Neighborhood Hits	27	Shared Neighborhood Hits	13
SwissProt Accessions	Q8IY31, Q5GLZ2, Q9BUG5	Gene names	IFT20
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 20 homolog (Intraflagellar transport protein 20) (hIFT20).

TRUB1_HUMAN
NC score	0.005229 (rank : 2622)	θ value	3.0926 (rank : 2229)
Query Neighborhood Hits	2923	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WWH5, Q53ES2	Gene names	TRUB1, PUS4
Domain Architecture	No domain graphic available
Description	Probable tRNA pseudouridine synthase 1 (EC 5.4.99.-).

FGD6_HUMAN
NC score	0.005185 (rank : 2623)	θ value	3.0926 (rank : 2168)
Query Neighborhood Hits	2923	Target Neighborhood Hits	237	Shared Neighborhood Hits	55
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

NIBL_MOUSE
NC score	0.005154 (rank : 2624)	θ value	6.88961 (rank : 2658)
Query Neighborhood Hits	2923	Target Neighborhood Hits	54	Shared Neighborhood Hits	26
SwissProt Accessions	Q8R1F1	Gene names
Domain Architecture	No domain graphic available
Description	Niban-like protein.

FXYD5_HUMAN
NC score	0.005145 (rank : 2625)	θ value	8.99809 (rank : 2783)
Query Neighborhood Hits	2923	Target Neighborhood Hits	30	Shared Neighborhood Hits	11
SwissProt Accessions	Q96DB9, Q6UW44, Q9HC34, Q9P039	Gene names	FXYD5, DYSAD, IWU1
Domain Architecture
Description	FXYD domain-containing ion transport regulator 5 precursor (Dysadherin).

CHD4_HUMAN
NC score	0.005141 (rank : 2626)	θ value	8.99809 (rank : 2752)
Query Neighborhood Hits	2923	Target Neighborhood Hits	365	Shared Neighborhood Hits	129
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

SEZ6L_HUMAN
NC score	0.005131 (rank : 2627)	θ value	1.38821 (rank : 1883)
Query Neighborhood Hits	2923	Target Neighborhood Hits	289	Shared Neighborhood Hits	75
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

G3BP_HUMAN
NC score	0.005131 (rank : 2628)	θ value	6.88961 (rank : 2605)
Query Neighborhood Hits	2923	Target Neighborhood Hits	219	Shared Neighborhood Hits	57
SwissProt Accessions	Q13283	Gene names	G3BP, G3BP1
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 1 (EC 3.6.1.-) (ATP- dependent DNA helicase VIII) (GAP SH3-domain-binding protein 1) (G3BP- 1) (HDH-VIII).

EPC1_MOUSE
NC score	0.005127 (rank : 2629)	θ value	3.0926 (rank : 2164)
Query Neighborhood Hits	2923	Target Neighborhood Hits	47	Shared Neighborhood Hits	20
SwissProt Accessions	Q8C9X6, Q9Z299	Gene names	Epc1
Domain Architecture	No domain graphic available
Description	Enhancer of polycomb homolog 1.

KIF9_HUMAN
NC score	0.005115 (rank : 2630)	θ value	1.06291 (rank : 1792)
Query Neighborhood Hits	2923	Target Neighborhood Hits	118	Shared Neighborhood Hits	55
SwissProt Accessions	Q9HAQ2, Q86Z28, Q9H8A4	Gene names	KIF9
Domain Architecture
Description	Kinesin-like protein KIF9.

INADL_MOUSE
NC score	0.005115 (rank : 2631)	θ value	1.81305 (rank : 1944)
Query Neighborhood Hits	2923	Target Neighborhood Hits	290	Shared Neighborhood Hits	72
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

SETB1_HUMAN
NC score	0.005102 (rank : 2632)	θ value	5.27518 (rank : 2509)
Query Neighborhood Hits	2923	Target Neighborhood Hits	141	Shared Neighborhood Hits	49
SwissProt Accessions	Q15047, Q96GM9	Gene names	SETDB1, KIAA0067
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

STAT6_HUMAN
NC score	0.005098 (rank : 2633)	θ value	1.38821 (rank : 1892)
Query Neighborhood Hits	2923	Target Neighborhood Hits	132	Shared Neighborhood Hits	50
SwissProt Accessions	P42226	Gene names	STAT6
Domain Architecture
Description	Signal transducer and activator of transcription 6 (IL-4 Stat).

SIL1_MOUSE
NC score	0.005008 (rank : 2634)	θ value	5.27518 (rank : 2513)
Query Neighborhood Hits	2923	Target Neighborhood Hits	68	Shared Neighborhood Hits	36
SwissProt Accessions	Q9EPK6, Q91V34	Gene names	Sil1
Domain Architecture	No domain graphic available
Description	Nucleotide exchange factor SIL1 precursor.

DYN2_HUMAN
NC score	0.004981 (rank : 2635)	θ value	5.27518 (rank : 2415)
Query Neighborhood Hits	2923	Target Neighborhood Hits	112	Shared Neighborhood Hits	47
SwissProt Accessions	P50570, Q7Z5S3, Q9UPH4	Gene names	DNM2, DYN2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5).

TIP60_MOUSE
NC score	0.004978 (rank : 2636)	θ value	6.88961 (rank : 2701)
Query Neighborhood Hits	2923	Target Neighborhood Hits	95	Shared Neighborhood Hits	44
SwissProt Accessions	Q8CHK4, Q8CGZ3, Q8CGZ4, Q8VIH0	Gene names	Htatip, Tip60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60).

MBIP1_MOUSE
NC score	0.004971 (rank : 2637)	θ value	6.88961 (rank : 2648)
Query Neighborhood Hits	2923	Target Neighborhood Hits	20	Shared Neighborhood Hits	10
SwissProt Accessions	Q99LQ1, Q3TBM3	Gene names	Mbip
Domain Architecture	No domain graphic available
Description	MAP3K12-binding inhibitory protein 1 (MAPK upstream kinase-binding inhibitory protein) (MUK-binding inhibitory protein).

KU86_MOUSE
NC score	0.004943 (rank : 2638)	θ value	4.03905 (rank : 2299)
Query Neighborhood Hits	2923	Target Neighborhood Hits	23	Shared Neighborhood Hits	12
SwissProt Accessions	P27641	Gene names	Xrcc5, G22p2
Domain Architecture
Description	ATP-dependent DNA helicase 2 subunit 2 (EC 3.6.1.-) (ATP-dependent DNA helicase II 80 kDa subunit) (Ku autoantigen protein p86 homolog) (Ku80) (CTC box-binding factor 85 kDa subunit) (CTCBF) (CTC85) (Nuclear factor IV) (DNA-repair protein XRCC5).

NHRF2_MOUSE
NC score	0.004931 (rank : 2639)	θ value	8.99809 (rank : 2843)
Query Neighborhood Hits	2923	Target Neighborhood Hits	194	Shared Neighborhood Hits	46
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

CACB2_HUMAN
NC score	0.004926 (rank : 2640)	θ value	3.0926 (rank : 2136)
Query Neighborhood Hits	2923	Target Neighborhood Hits	99	Shared Neighborhood Hits	29
SwissProt Accessions	Q08289, O00304, Q8WX81, Q96NZ3, Q96NZ4, Q96NZ5, Q9BWU2, Q9HD32, Q9Y340, Q9Y341	Gene names	CACNB2, CACNLB2, MYSB
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2) (Lambert-Eaton myasthenic syndrome antigen B) (MYSB).

PSMD1_HUMAN
NC score	0.004919 (rank : 2641)	θ value	6.88961 (rank : 2678)
Query Neighborhood Hits	2923	Target Neighborhood Hits	42	Shared Neighborhood Hits	25
SwissProt Accessions	Q99460, Q53TI2, Q6GMU5, Q6P2P4, Q6PJM7, Q6PKG9, Q86VU1, Q8IV79	Gene names	PSMD1
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory subunit RPN2) (26S proteasome regulatory subunit S1) (26S proteasome subunit p112).

CPNE3_HUMAN
NC score	0.004917 (rank : 2642)	θ value	3.0926 (rank : 2148)
Query Neighborhood Hits	2923	Target Neighborhood Hits	90	Shared Neighborhood Hits	14
SwissProt Accessions	O75131, Q8IYA1	Gene names	CPNE3, CPN3, KIAA0636
Domain Architecture
Description	Copine-3 (Copine III).

PAR14_MOUSE
NC score	0.004888 (rank : 2643)	θ value	0.279714 (rank : 1514)
Query Neighborhood Hits	2923	Target Neighborhood Hits	113	Shared Neighborhood Hits	36
SwissProt Accessions	Q2EMV9, Q571C6, Q8BN35, Q8VDT6	Gene names	Parp14, Kiaa1268
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 14 (EC 2.4.2.30) (PARP-14) (Collaborator of STAT6) (CoaSt6).

CCNL1_HUMAN
NC score	0.004853 (rank : 2644)	θ value	2.36792 (rank : 2023)
Query Neighborhood Hits	2923	Target Neighborhood Hits	79	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UK58, Q6NVY9, Q6UWS7, Q8NI48, Q96QT0, Q9NZF3	Gene names	CCNL1
Domain Architecture	No domain graphic available
Description	Cyclin-L1 (Cyclin-L).

CF057_MOUSE
NC score	0.004840 (rank : 2645)	θ value	6.88961 (rank : 2565)
Query Neighborhood Hits	2923	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BTE0, Q9CQN5, Q9D537	Gene names
Domain Architecture	No domain graphic available
Description	UPF0369 protein C6orf57 homolog precursor.

PLIN_HUMAN
NC score	0.004840 (rank : 2646)	θ value	5.27518 (rank : 2494)
Query Neighborhood Hits	2923	Target Neighborhood Hits	37	Shared Neighborhood Hits	14
SwissProt Accessions	O60240, Q8N5Y6	Gene names	PLIN
Domain Architecture
Description	Perilipin (PERI) (Lipid droplet-associated protein).

CPNE3_MOUSE
NC score	0.004800 (rank : 2647)	θ value	4.03905 (rank : 2267)
Query Neighborhood Hits	2923	Target Neighborhood Hits	90	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BT60, Q5CZX9, Q5DU22	Gene names	Cpne3, Kiaa0636
Domain Architecture
Description	Copine-3 (Copine III).

SYT12_MOUSE
NC score	0.004799 (rank : 2648)	θ value	8.99809 (rank : 2892)
Query Neighborhood Hits	2923	Target Neighborhood Hits	102	Shared Neighborhood Hits	16
SwissProt Accessions	Q920N7	Gene names	Syt12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

RNZ2_HUMAN
NC score	0.004779 (rank : 2649)	θ value	1.81305 (rank : 1975)
Query Neighborhood Hits	2923	Target Neighborhood Hits	17	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BQ52, Q9HAS8, Q9HAS9, Q9NVT1	Gene names	ELAC2, HPC2
Domain Architecture
Description	Zinc phosphodiesterase ELAC protein 2 (EC 3.1.26.11) (Ribonuclease Z 2) (RNase Z 2) (tRNase Z 2) (tRNA 3 endonuclease 2) (ElaC homolog protein 2) (Heredity prostate cancer protein 2).

TIP60_HUMAN
NC score	0.004767 (rank : 2650)	θ value	6.88961 (rank : 2700)
Query Neighborhood Hits	2923	Target Neighborhood Hits	90	Shared Neighborhood Hits	43
SwissProt Accessions	Q92993, O95624, Q13430, Q6GSE8, Q9BWK7	Gene names	HTATIP, TIP60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60) (HIV-1 Tat interactive protein) (cPLA(2)-interacting protein).

WDR46_HUMAN
NC score	0.004705 (rank : 2651)	θ value	1.06291 (rank : 1817)
Query Neighborhood Hits	2923	Target Neighborhood Hits	147	Shared Neighborhood Hits	24
SwissProt Accessions	O15213, Q5STK5	Gene names	WDR46, BING4, C6orf11
Domain Architecture
Description	WD repeat protein 46 (WD repeat protein BING4).

B4GN4_MOUSE
NC score	0.004695 (rank : 2652)	θ value	0.813845 (rank : 1704)
Query Neighborhood Hits	2923	Target Neighborhood Hits	129	Shared Neighborhood Hits	36
SwissProt Accessions	Q766D5, Q8CHV2	Gene names	B4galnt4
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 1 (EC 2.4.1.244) (NGalNAc-T1) (Beta- 1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4).

DLG1_HUMAN
NC score	0.004671 (rank : 2653)	θ value	6.88961 (rank : 2584)
Query Neighborhood Hits	2923	Target Neighborhood Hits	290	Shared Neighborhood Hits	70
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

FBX24_MOUSE
NC score	0.004663 (rank : 2654)	θ value	6.88961 (rank : 2601)
Query Neighborhood Hits	2923	Target Neighborhood Hits	59	Shared Neighborhood Hits	10
SwissProt Accessions	Q9D417	Gene names	Fbxo24, Fbx24
Domain Architecture	No domain graphic available
Description	F-box only protein 24.

PHYIP_MOUSE
NC score	0.004597 (rank : 2655)	θ value	6.88961 (rank : 2672)
Query Neighborhood Hits	2923	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K0S0	Gene names	Phyhip
Domain Architecture
Description	Phytanoyl-CoA hydroxylase-interacting protein (Phytanoyl-CoA hydroxylase-associated protein 1) (PAHXAP1) (PAHX-AP1).

PHYIP_HUMAN
NC score	0.004597 (rank : 2656)	θ value	6.88961 (rank : 2671)
Query Neighborhood Hits	2923	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	Q92561, Q8N4I9	Gene names	PHYHIP, KIAA0273
Domain Architecture
Description	Phytanoyl-CoA hydroxylase-interacting protein (Phytanoyl-CoA hydroxylase-associated protein 1) (PAHXAP1) (PAHX-AP1).

EME1_HUMAN
NC score	0.004568 (rank : 2657)	θ value	8.99809 (rank : 2775)
Query Neighborhood Hits	2923	Target Neighborhood Hits	31	Shared Neighborhood Hits	17
SwissProt Accessions	Q96AY2, Q96N62	Gene names	EME1, MMS4
Domain Architecture	No domain graphic available
Description	Crossover junction endonuclease EME1 (EC 3.1.22.-) (hMMS4).

FBX24_HUMAN
NC score	0.004568 (rank : 2658)	θ value	6.88961 (rank : 2600)
Query Neighborhood Hits	2923	Target Neighborhood Hits	57	Shared Neighborhood Hits	8
SwissProt Accessions	O75426, Q9H0G1	Gene names	FBXO24, FBX24
Domain Architecture
Description	F-box only protein 24.

PSMD1_MOUSE
NC score	0.004550 (rank : 2659)	θ value	6.88961 (rank : 2679)
Query Neighborhood Hits	2923	Target Neighborhood Hits	42	Shared Neighborhood Hits	27
SwissProt Accessions	Q3TXS7	Gene names	Psmd1
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory subunit RPN2) (26S proteasome regulatory subunit S1).

HB21_MOUSE
NC score	0.004543 (rank : 2660)	θ value	0.279714 (rank : 1502)
Query Neighborhood Hits	2923	Target Neighborhood Hits	213	Shared Neighborhood Hits	60
SwissProt Accessions	P04230, O78226	Gene names	H2-Eb1
Domain Architecture
Description	H-2 class II histocompatibility antigen, E-B beta chain precursor.

NFAT5_MOUSE
NC score	0.004495 (rank : 2661)	θ value	5.27518 (rank : 2468)
Query Neighborhood Hits	2923	Target Neighborhood Hits	162	Shared Neighborhood Hits	60
SwissProt Accessions	Q9WV30	Gene names	Nfat5
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T cell transcription factor NFAT5) (NF-AT5) (Rel domain-containing transcription factor NFAT5).

PLXB1_HUMAN
NC score	0.004455 (rank : 2662)	θ value	3.0926 (rank : 2210)
Query Neighborhood Hits	2923	Target Neighborhood Hits	360	Shared Neighborhood Hits	128
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

HB2I_MOUSE
NC score	0.004414 (rank : 2663)	θ value	0.279714 (rank : 1504)
Query Neighborhood Hits	2923	Target Neighborhood Hits	211	Shared Neighborhood Hits	59
SwissProt Accessions	P18468	Gene names	H2-Eb1
Domain Architecture
Description	H-2 class II histocompatibility antigen, I-A beta chain precursor.

2B1A_HUMAN
NC score	0.004411 (rank : 2664)	θ value	0.125558 (rank : 1382)
Query Neighborhood Hits	2923	Target Neighborhood Hits	211	Shared Neighborhood Hits	60
SwissProt Accessions	Q30167, Q9MYF5	Gene names	HLA-DRB1
Domain Architecture
Description	HLA class II histocompatibility antigen, DRB1-10 beta chain precursor (MHC class I antigen DRB1*10) (DRw10).

TVC_HUMAN
NC score	0.004383 (rank : 2665)	θ value	5.27518 (rank : 2526)
Query Neighborhood Hits	2923	Target Neighborhood Hits	179	Shared Neighborhood Hits	63
SwissProt Accessions	P03979	Gene names	TCRB
Domain Architecture
Description	T-cell receptor gamma chain V region PT-gamma-1/2 precursor.

RL7_MOUSE
NC score	0.004361 (rank : 2666)	θ value	4.03905 (rank : 2344)
Query Neighborhood Hits	2923	Target Neighborhood Hits	15	Shared Neighborhood Hits	9
SwissProt Accessions	P14148, Q80UR0	Gene names	Rpl7
Domain Architecture
Description	60S ribosomal protein L7.

LYPD3_HUMAN
NC score	0.004354 (rank : 2667)	θ value	5.27518 (rank : 2457)
Query Neighborhood Hits	2923	Target Neighborhood Hits	43	Shared Neighborhood Hits	15
SwissProt Accessions	O95274, Q9UJ74	Gene names	LYPD3, C4.4A
Domain Architecture	No domain graphic available
Description	Ly6/PLAUR domain-containing protein 3 precursor (GPI-anchored metastasis-associated protein C4.4A homolog) (Matrigel-induced gene C4 protein) (MIG-C4).

DYN2_MOUSE
NC score	0.004332 (rank : 2668)	θ value	6.88961 (rank : 2590)
Query Neighborhood Hits	2923	Target Neighborhood Hits	104	Shared Neighborhood Hits	40
SwissProt Accessions	P39054, Q9DBE1	Gene names	Dnm2, Dyn2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5) (Dynamin UDNM).

EPC1_HUMAN
NC score	0.004260 (rank : 2669)	θ value	8.99809 (rank : 2778)
Query Neighborhood Hits	2923	Target Neighborhood Hits	60	Shared Neighborhood Hits	32
SwissProt Accessions	Q9H2F5, Q5VW54, Q5VW56, Q5VW58, Q8NAQ4, Q8NE21, Q96LF4, Q96RR6, Q9H7T7	Gene names	EPC1
Domain Architecture	No domain graphic available
Description	Enhancer of polycomb homolog 1.

RBPMS_MOUSE
NC score	0.004241 (rank : 2670)	θ value	3.0926 (rank : 2216)
Query Neighborhood Hits	2923	Target Neighborhood Hits	47	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WVB0	Gene names	Rbpms, Hermes
Domain Architecture
Description	RNA-binding protein with multiple splicing (RBP-MS) (HEart, RRM Expressed Sequence) (Hermes).

LV3B_HUMAN
NC score	0.004149 (rank : 2671)	θ value	0.47712 (rank : 1612)
Query Neighborhood Hits	2923	Target Neighborhood Hits	232	Shared Neighborhood Hits	81
SwissProt Accessions	P80748	Gene names
Domain Architecture	No domain graphic available
Description	Ig lambda chain V-III region LOI.

HB24_MOUSE
NC score	0.004136 (rank : 2672)	θ value	0.279714 (rank : 1503)
Query Neighborhood Hits	2923	Target Neighborhood Hits	213	Shared Neighborhood Hits	59
SwissProt Accessions	P20040	Gene names
Domain Architecture
Description	H-2 class II histocompatibility antigen, E-Q beta chain precursor (E- W17).

SPAG7_MOUSE
NC score	0.004125 (rank : 2673)	θ value	8.99809 (rank : 2886)
Query Neighborhood Hits	2923	Target Neighborhood Hits	21	Shared Neighborhood Hits	13
SwissProt Accessions	Q7TNE3, Q3TM27, Q80XJ8, Q8BK16	Gene names	Spag7
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 7.

SEM6C_MOUSE
NC score	0.004073 (rank : 2674)	θ value	8.99809 (rank : 2876)
Query Neighborhood Hits	2923	Target Neighborhood Hits	352	Shared Neighborhood Hits	109
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

ARHG1_HUMAN
NC score	0.004069 (rank : 2675)	θ value	0.47712 (rank : 1586)
Query Neighborhood Hits	2923	Target Neighborhood Hits	176	Shared Neighborhood Hits	51
SwissProt Accessions	Q92888, O00513, Q8N4J4, Q96BF4, Q96F17, Q9BSB1	Gene names	ARHGEF1
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide exchange factor) (Sub1.5).

SRBP2_HUMAN
NC score	0.004060 (rank : 2676)	θ value	1.81305 (rank : 1986)
Query Neighborhood Hits	2923	Target Neighborhood Hits	133	Shared Neighborhood Hits	31
SwissProt Accessions	Q12772, Q9UH04	Gene names	SREBF2, SREBP2
Domain Architecture
Description	Sterol regulatory element-binding protein 2 (SREBP-2) (Sterol regulatory element-binding transcription factor 2).

RL6_HUMAN
NC score	0.003985 (rank : 2677)	θ value	8.99809 (rank : 2867)
Query Neighborhood Hits	2923	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	Q02878, Q2M3Q3, Q8WW97	Gene names	RPL6
Domain Architecture
Description	60S ribosomal protein L6 (TAX-responsive enhancer element-binding protein 107) (TAXREB107) (Neoplasm-related protein C140).

CACB2_MOUSE
NC score	0.003946 (rank : 2678)	θ value	3.0926 (rank : 2137)
Query Neighborhood Hits	2923	Target Neighborhood Hits	94	Shared Neighborhood Hits	20
SwissProt Accessions	Q8CC27, Q8C5J5, Q9CTQ6	Gene names	Cacnb2, Cacnlb2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2).

BRD7_MOUSE
NC score	0.003940 (rank : 2679)	θ value	6.88961 (rank : 2553)
Query Neighborhood Hits	2923	Target Neighborhood Hits	141	Shared Neighborhood Hits	63
SwissProt Accessions	O88665, Q3UQ56, Q3UU06, Q9CT78	Gene names	Brd7, Bp75
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein).

KIF1C_MOUSE
NC score	0.003935 (rank : 2680)	θ value	6.88961 (rank : 2629)
Query Neighborhood Hits	2923	Target Neighborhood Hits	171	Shared Neighborhood Hits	84
SwissProt Accessions	O35071, Q5SX62	Gene names	Kif1c
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF1C.

CAPS1_MOUSE
NC score	0.003924 (rank : 2681)	θ value	8.99809 (rank : 2744)
Query Neighborhood Hits	2923	Target Neighborhood Hits	93	Shared Neighborhood Hits	43
SwissProt Accessions	Q80TJ1, Q3TSP2, Q61374, Q6AXB4, Q6PGF0	Gene names	Cadps, Caps, Caps1, Kiaa1121
Domain Architecture	No domain graphic available
Description	Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1).

CYH2_HUMAN
NC score	0.003918 (rank : 2682)	θ value	8.99809 (rank : 2761)
Query Neighborhood Hits	2923	Target Neighborhood Hits	175	Shared Neighborhood Hits	54
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

GFPT2_HUMAN
NC score	0.003904 (rank : 2683)	θ value	1.81305 (rank : 1937)
Query Neighborhood Hits	2923	Target Neighborhood Hits	14	Shared Neighborhood Hits	5
SwissProt Accessions	O94808, Q53XM2, Q9BWS4	Gene names	GFPT2
Domain Architecture
Description	Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 2 (EC 2.6.1.16) (Hexosephosphate aminotransferase 2) (D-fructose-6- phosphate amidotransferase 2) (GFAT 2) (GFAT2).

DOCK2_MOUSE
NC score	0.003867 (rank : 2684)	θ value	1.38821 (rank : 1838)
Query Neighborhood Hits	2923	Target Neighborhood Hits	104	Shared Neighborhood Hits	32
SwissProt Accessions	Q8C3J5, Q99M79	Gene names	Dock2
Domain Architecture
Description	Dedicator of cytokinesis protein 2 (Hch protein).

HPS5_MOUSE
NC score	0.003865 (rank : 2685)	θ value	6.88961 (rank : 2620)
Query Neighborhood Hits	2923	Target Neighborhood Hits	69	Shared Neighborhood Hits	28
SwissProt Accessions	P59438	Gene names	Hps5, Ru2
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 5 protein homolog (Ruby-eye protein 2) (Ru2).

CAC1A_HUMAN
NC score	0.003839 (rank : 2686)	θ value	6.88961 (rank : 2556)
Query Neighborhood Hits	2923	Target Neighborhood Hits	387	Shared Neighborhood Hits	128
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

HDAC7_MOUSE
NC score	0.003822 (rank : 2687)	θ value	0.813845 (rank : 1726)
Query Neighborhood Hits	2923	Target Neighborhood Hits	85	Shared Neighborhood Hits	33
SwissProt Accessions	Q8C2B3, Q8C2C9, Q8C8X4, Q8CB80, Q8CDA3, Q9JL72	Gene names	Hdac7a, Hdac7
Domain Architecture
Description	Histone deacetylase 7a (HD7a).

JHD3C_HUMAN
NC score	0.003805 (rank : 2688)	θ value	1.38821 (rank : 1855)
Query Neighborhood Hits	2923	Target Neighborhood Hits	91	Shared Neighborhood Hits	33
SwissProt Accessions	Q9H3R0, O94877, Q2M3M0, Q5JUC9, Q5VYJ2, Q5VYJ3	Gene names	JMJD2C, GASC1, JHDM3C, KIAA0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C) (Gene amplified in squamous cell carcinoma 1 protein) (GASC-1 protein).

CAC1H_HUMAN
NC score	0.003804 (rank : 2689)	θ value	0.279714 (rank : 1484)
Query Neighborhood Hits	2923	Target Neighborhood Hits	307	Shared Neighborhood Hits	87
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

HB2J_MOUSE
NC score	0.003781 (rank : 2690)	θ value	0.279714 (rank : 1505)
Query Neighborhood Hits	2923	Target Neighborhood Hits	214	Shared Neighborhood Hits	59
SwissProt Accessions	P18469	Gene names	H2-Eb1
Domain Architecture
Description	H-2 class II histocompatibility antigen, I-E beta chain precursor.

SYNJ2_MOUSE
NC score	0.003780 (rank : 2691)	θ value	8.99809 (rank : 2891)
Query Neighborhood Hits	2923	Target Neighborhood Hits	87	Shared Neighborhood Hits	42
SwissProt Accessions	Q9D2G5, O35404, O88399, O88400, O88401, O88402, O88403, O88404	Gene names	Synj2, Kiaa0348
Domain Architecture
Description	Synaptojanin-2 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 2).

CHRD_MOUSE
NC score	0.003764 (rank : 2692)	θ value	0.62314 (rank : 1657)
Query Neighborhood Hits	2923	Target Neighborhood Hits	102	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Z0E2	Gene names	Chrd
Domain Architecture
Description	Chordin precursor.

CYH2_MOUSE
NC score	0.003739 (rank : 2693)	θ value	8.99809 (rank : 2762)
Query Neighborhood Hits	2923	Target Neighborhood Hits	171	Shared Neighborhood Hits	53
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

MD2BP_MOUSE
NC score	0.003718 (rank : 2694)	θ value	5.27518 (rank : 2462)
Query Neighborhood Hits	2923	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	Q9DCX1, Q99J05, Q9D0Y3	Gene names	Mad2l1bp, Mad2lbp
Domain Architecture
Description	MAD2L1-binding protein.

PDCD2_MOUSE
NC score	0.003705 (rank : 2695)	θ value	5.27518 (rank : 2487)
Query Neighborhood Hits	2923	Target Neighborhood Hits	29	Shared Neighborhood Hits	5
SwissProt Accessions	P46718, Q8BR06	Gene names	Pdcd2, Rp8
Domain Architecture
Description	Programmed cell death protein 2 (Zinc finger protein Rp-8).

SMCA1_MOUSE
NC score	0.003693 (rank : 2696)	θ value	0.279714 (rank : 1522)
Query Neighborhood Hits	2923	Target Neighborhood Hits	117	Shared Neighborhood Hits	46
SwissProt Accessions	Q6PGB8, Q8BSS1, Q91Y58	Gene names	Smarca1, Snf2l
Domain Architecture	No domain graphic available
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1) (DNA-dependent ATPase SNF2L).

RPGF1_HUMAN
NC score	0.003688 (rank : 2697)	θ value	1.81305 (rank : 1976)
Query Neighborhood Hits	2923	Target Neighborhood Hits	262	Shared Neighborhood Hits	81
SwissProt Accessions	Q13905	Gene names	RAPGEF1, GRF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP).

F10A1_HUMAN
NC score	0.003666 (rank : 2698)	θ value	6.88961 (rank : 2596)
Query Neighborhood Hits	2923	Target Neighborhood Hits	312	Shared Neighborhood Hits	102
SwissProt Accessions	P50502, O14999	Gene names	ST13, FAM10A1, HIP, SNC6
Domain Architecture
Description	Hsc70-interacting protein (Hip) (Suppression of tumorigenicity protein 13) (Putative tumor suppressor ST13) (Protein FAM10A1) (Progesterone receptor-associated p48 protein) (NY-REN-33 antigen).

IDH3A_MOUSE
NC score	0.003642 (rank : 2699)	θ value	2.36792 (rank : 2058)
Query Neighborhood Hits	2923	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D6R2, Q3UAM8, Q8C8A1, Q9D1L1	Gene names	Idh3a
Domain Architecture	No domain graphic available
Description	Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH).

GFPT2_MOUSE
NC score	0.003630 (rank : 2700)	θ value	2.36792 (rank : 2049)
Query Neighborhood Hits	2923	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z2Z9	Gene names	Gfpt2
Domain Architecture
Description	Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 2 (EC 2.6.1.16) (Hexosephosphate aminotransferase 2) (D-fructose-6- phosphate amidotransferase 2) (GFAT 2) (GFAT2).

FA8_HUMAN
NC score	0.003629 (rank : 2701)	θ value	3.0926 (rank : 2167)
Query Neighborhood Hits	2923	Target Neighborhood Hits	112	Shared Neighborhood Hits	31
SwissProt Accessions	P00451	Gene names	F8, F8C
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component) (Antihemophilic factor) (AHF) [Contains: Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIII B chain; Factor VIIIa light chain].

TXND5_HUMAN
NC score	0.003629 (rank : 2702)	θ value	4.03905 (rank : 2364)
Query Neighborhood Hits	2923	Target Neighborhood Hits	54	Shared Neighborhood Hits	12
SwissProt Accessions	Q8NBS9, Q8ND33, Q8TCT2, Q9BVH9	Gene names	TXNDC5, TLP46
Domain Architecture
Description	Thioredoxin domain-containing protein 5 precursor (Thioredoxin-like protein p46) (Endoplasmic reticulum protein ERp46).

MYLIP_MOUSE
NC score	0.003614 (rank : 2703)	θ value	8.99809 (rank : 2837)
Query Neighborhood Hits	2923	Target Neighborhood Hits	139	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

ITPR1_MOUSE
NC score	0.003581 (rank : 2704)	θ value	0.813845 (rank : 1731)
Query Neighborhood Hits	2923	Target Neighborhood Hits	99	Shared Neighborhood Hits	40
SwissProt Accessions	P11881, P20943, Q99LG5	Gene names	Itpr1, Insp3r, Pcd6, Pcp1
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 1 (Type 1 inositol 1,4,5- trisphosphate receptor) (Type 1 InsP3 receptor) (IP3 receptor isoform 1) (InsP3R1) (Inositol 1,4,5-trisphosphate-binding protein P400) (Purkinje cell protein 1) (Protein PCD-6).

RNF17_MOUSE
NC score	0.003578 (rank : 2705)	θ value	6.88961 (rank : 2685)
Query Neighborhood Hits	2923	Target Neighborhood Hits	147	Shared Neighborhood Hits	54
SwissProt Accessions	Q99MV7	Gene names	Rnf17
Domain Architecture
Description	RING finger protein 17.

HRBL_HUMAN
NC score	0.003574 (rank : 2706)	θ value	5.27518 (rank : 2438)
Query Neighborhood Hits	2923	Target Neighborhood Hits	179	Shared Neighborhood Hits	48
SwissProt Accessions	O95081, O75429, Q96AB9, Q96GL4	Gene names	HRBL, RABR
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

HB22_MOUSE
NC score	0.003567 (rank : 2707)	θ value	0.813845 (rank : 1724)
Query Neighborhood Hits	2923	Target Neighborhood Hits	210	Shared Neighborhood Hits	57
SwissProt Accessions	P01915	Gene names
Domain Architecture	No domain graphic available
Description	H-2 class II histocompatibility antigen, E-D beta chain precursor.

2DMB_HUMAN
NC score	0.003492 (rank : 2708)	θ value	5.27518 (rank : 2373)
Query Neighborhood Hits	2923	Target Neighborhood Hits	216	Shared Neighborhood Hits	63
SwissProt Accessions	P28068, O77936, Q13012, Q29751, Q9XRX2	Gene names	HLA-DMB, DMB, RING7
Domain Architecture
Description	HLA class II histocompatibility antigen, DM beta chain precursor (MHC class II antigen DMB).

IL16_HUMAN
NC score	0.003474 (rank : 2709)	θ value	1.38821 (rank : 1852)
Query Neighborhood Hits	2923	Target Neighborhood Hits	207	Shared Neighborhood Hits	54
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

PDLI7_HUMAN
NC score	0.003446 (rank : 2710)	θ value	0.813845 (rank : 1740)
Query Neighborhood Hits	2923	Target Neighborhood Hits	547	Shared Neighborhood Hits	154
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

TR95_MOUSE
NC score	0.003397 (rank : 2711)	θ value	1.81305 (rank : 1998)
Query Neighborhood Hits	2923	Target Neighborhood Hits	95	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PGF3	Gene names	Thrap5
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein complex 95 kDa component (Trap95) (Thyroid hormone receptor-associated protein 5) (Vitamin D3 receptor-interacting protein complex component DRIP92).

DPOLA_HUMAN
NC score	0.003359 (rank : 2712)	θ value	4.03905 (rank : 2273)
Query Neighborhood Hits	2923	Target Neighborhood Hits	41	Shared Neighborhood Hits	13
SwissProt Accessions	P09884, Q86UQ7	Gene names	POLA1, POLA
Domain Architecture
Description	DNA polymerase alpha catalytic subunit (EC 2.7.7.7).

HB2C_HUMAN
NC score	0.003341 (rank : 2713)	θ value	0.365318 (rank : 1551)
Query Neighborhood Hits	2923	Target Neighborhood Hits	211	Shared Neighborhood Hits	59
SwissProt Accessions	P01914	Gene names
Domain Architecture
Description	HLA class II histocompatibility antigen, DR-1 beta chain precursor (Clone P2-beta-4).

HDAC7_HUMAN
NC score	0.003305 (rank : 2714)	θ value	0.813845 (rank : 1725)
Query Neighborhood Hits	2923	Target Neighborhood Hits	64	Shared Neighborhood Hits	22
SwissProt Accessions	Q8WUI4, Q7Z5I1, Q96K01, Q9BR73, Q9H7L0, Q9NW41, Q9NWA9, Q9NYK9, Q9UFU7	Gene names	HDAC7A, HDAC7
Domain Architecture
Description	Histone deacetylase 7a (HD7a).

K1024_HUMAN
NC score	0.003285 (rank : 2715)	θ value	4.03905 (rank : 2298)
Query Neighborhood Hits	2923	Target Neighborhood Hits	66	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UPX6	Gene names	KIAA1024
Domain Architecture
Description	UPF0258 protein KIAA1024.

DNPEP_HUMAN
NC score	0.003276 (rank : 2716)	θ value	6.88961 (rank : 2585)
Query Neighborhood Hits	2923	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ULA0, Q9BW44, Q9NUV5	Gene names	DNPEP
Domain Architecture
Description	Aspartyl aminopeptidase (EC 3.4.11.21).

JHD1B_MOUSE
NC score	0.003268 (rank : 2717)	θ value	1.81305 (rank : 1946)
Query Neighborhood Hits	2923	Target Neighborhood Hits	214	Shared Neighborhood Hits	77
SwissProt Accessions	Q6P1G2, Q3V396, Q6PFD0, Q6ZPE8, Q9CSF7, Q9QZN6	Gene names	Fbxl10, Fbl10, Jhdm1b, Kiaa3014
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10).

SCML2_HUMAN
NC score	0.003242 (rank : 2718)	θ value	1.06291 (rank : 1811)
Query Neighborhood Hits	2923	Target Neighborhood Hits	68	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UQR0, Q86U98, Q8IWD0, Q8NDP2, Q9UGC5	Gene names	SCML2
Domain Architecture
Description	Sex comb on midleg-like protein 2.

DONS_HUMAN
NC score	0.003225 (rank : 2719)	θ value	5.27518 (rank : 2412)
Query Neighborhood Hits	2923	Target Neighborhood Hits	16	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NYP3, Q9NSR9, Q9NVZ5, Q9NYP1, Q9NYP2	Gene names	DONSON, C21orf60
Domain Architecture	No domain graphic available
Description	Protein downstream neighbor of Son (B17).

TRM1_HUMAN
NC score	0.003218 (rank : 2720)	θ value	6.88961 (rank : 2705)
Query Neighborhood Hits	2923	Target Neighborhood Hits	37	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NXH9, O76103, Q548Y5, Q8WVA6	Gene names	TRMT1
Domain Architecture
Description	N(2),N(2)-dimethylguanosine tRNA methyltransferase (EC 2.1.1.32) (tRNA(guanine-26,N(2)-N(2)) methyltransferase) (tRNA 2,2- dimethylguanosine-26 methyltransferase) (tRNA(m(2,2)G26)dimethyltransferase).

IDH3A_HUMAN
NC score	0.003215 (rank : 2721)	θ value	4.03905 (rank : 2293)
Query Neighborhood Hits	2923	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	P50213, Q9H3X0	Gene names	IDH3A
Domain Architecture
Description	Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH).

DNPEP_MOUSE
NC score	0.003206 (rank : 2722)	θ value	6.88961 (rank : 2586)
Query Neighborhood Hits	2923	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z2W0	Gene names	Dnpep
Domain Architecture
Description	Aspartyl aminopeptidase (EC 3.4.11.21).

SOX5_HUMAN
NC score	0.003099 (rank : 2723)	θ value	5.27518 (rank : 2517)
Query Neighborhood Hits	2923	Target Neighborhood Hits	219	Shared Neighborhood Hits	85
SwissProt Accessions	P35711, Q86UK8, Q8J017, Q8J018, Q8J019, Q8J020, Q8N1D9, Q8N7E0, Q8TEA4	Gene names	SOX5
Domain Architecture
Description	Transcription factor SOX-5.

ADA12_MOUSE
NC score	0.003068 (rank : 2724)	θ value	1.81305 (rank : 1902)
Query Neighborhood Hits	2923	Target Neighborhood Hits	474	Shared Neighborhood Hits	141
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

FA53B_MOUSE
NC score	0.003044 (rank : 2725)	θ value	6.88961 (rank : 2598)
Query Neighborhood Hits	2923	Target Neighborhood Hits	29	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BGR5, Q3UGW1, Q8BI13	Gene names	Fam53b
Domain Architecture	No domain graphic available
Description	Protein FAM53B.

KIF2C_HUMAN
NC score	0.003017 (rank : 2726)	θ value	2.36792 (rank : 2068)
Query Neighborhood Hits	2923	Target Neighborhood Hits	138	Shared Neighborhood Hits	62
SwissProt Accessions	Q99661, Q96C18, Q96HB8, Q9BWV8	Gene names	KIF2C, KNSL6
Domain Architecture
Description	Kinesin-like protein KIF2C (Mitotic centromere-associated kinesin) (MCAK) (Kinesin-like protein 6).

NUCL_HUMAN
NC score	0.002982 (rank : 2727)	θ value	3.0926 (rank : 2200)
Query Neighborhood Hits	2923	Target Neighborhood Hits	415	Shared Neighborhood Hits	99
SwissProt Accessions	P19338, Q53SK1, Q8NB06	Gene names	NCL
Domain Architecture
Description	Nucleolin (Protein C23).

K1958_HUMAN
NC score	0.002920 (rank : 2728)	θ value	8.99809 (rank : 2807)
Query Neighborhood Hits	2923	Target Neighborhood Hits	76	Shared Neighborhood Hits	26
SwissProt Accessions	Q8N8K9, Q5T252, Q8TF43, Q96N02	Gene names	KIAA1958
Domain Architecture	No domain graphic available
Description	Protein KIAA1958.

CAPS1_HUMAN
NC score	0.002909 (rank : 2729)	θ value	8.99809 (rank : 2743)
Query Neighborhood Hits	2923	Target Neighborhood Hits	86	Shared Neighborhood Hits	38
SwissProt Accessions	Q9ULU8, Q13339, Q6GQQ6, Q8N2Z5, Q8N3M7, Q8NFR0, Q96BC2	Gene names	CADPS, CAPS, CAPS1, KIAA1121
Domain Architecture	No domain graphic available
Description	Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1).

PDCD2_HUMAN
NC score	0.002893 (rank : 2730)	θ value	6.88961 (rank : 2670)
Query Neighborhood Hits	2923	Target Neighborhood Hits	29	Shared Neighborhood Hits	6
SwissProt Accessions	Q16342, Q9UH12	Gene names	PDCD2, RP8, ZMYND7
Domain Architecture
Description	Programmed cell death protein 2 (Zinc finger protein Rp-8) (Zinc finger MYND domain-containing protein 7).

SG1D1_HUMAN
NC score	0.002868 (rank : 2731)	θ value	8.99809 (rank : 2878)
Query Neighborhood Hits	2923	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	O95968	Gene names	SCGB1D1, LIPHA
Domain Architecture
Description	Lipophilin-A precursor (Secretoglobin family 1D member 1).

TM1L1_MOUSE
NC score	0.002864 (rank : 2732)	θ value	2.36792 (rank : 2110)
Query Neighborhood Hits	2923	Target Neighborhood Hits	43	Shared Neighborhood Hits	16
SwissProt Accessions	Q923U0, Q99KE0, Q9D6Y5	Gene names	Tom1l1, Srcasm
Domain Architecture
Description	TOM1-like 1 protein (Target of myb-like 1 protein) (Src-activating and signaling molecule protein).

DPPA2_HUMAN
NC score	0.002773 (rank : 2733)	θ value	6.88961 (rank : 2589)
Query Neighborhood Hits	2923	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z7J5, Q8WVF0	Gene names	DPPA2, PESCRG1
Domain Architecture	No domain graphic available
Description	Developmental pluripotency-associated protein 2 (Pluripotent embryonic stem cell-related protein 1).

VPP4_MOUSE
NC score	0.002763 (rank : 2734)	θ value	2.36792 (rank : 2120)
Query Neighborhood Hits	2923	Target Neighborhood Hits	35	Shared Neighborhood Hits	14
SwissProt Accessions	Q920R6, Q8CJ79, Q920B5	Gene names	Atp6v0a4, Atp6n1b
Domain Architecture
Description	Vacuolar proton translocating ATPase 116 kDa subunit a isoform 4 (V- ATPase 116 kDa isoform a4) (Vacuolar proton translocating ATPase 116 kDa subunit a kidney isoform).

RB_MOUSE
NC score	0.002752 (rank : 2735)	θ value	5.27518 (rank : 2498)
Query Neighborhood Hits	2923	Target Neighborhood Hits	31	Shared Neighborhood Hits	10
SwissProt Accessions	P13405	Gene names	Rb1, Rb-1
Domain Architecture
Description	Retinoblastoma-associated protein (PP105) (RB).

SAP_MOUSE
NC score	0.002740 (rank : 2736)	θ value	4.03905 (rank : 2351)
Query Neighborhood Hits	2923	Target Neighborhood Hits	22	Shared Neighborhood Hits	6
SwissProt Accessions	Q61207, Q60861, Q64006, Q64219	Gene names	Psap, Sgp1
Domain Architecture
Description	Sulfated glycoprotein 1 precursor (SGP-1) (Prosaposin).

UBP10_HUMAN
NC score	0.002612 (rank : 2737)	θ value	2.36792 (rank : 2117)
Query Neighborhood Hits	2923	Target Neighborhood Hits	153	Shared Neighborhood Hits	38
SwissProt Accessions	Q14694, Q9BWG7, Q9NSL7	Gene names	USP10, KIAA0190
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

AGM1_MOUSE
NC score	0.002586 (rank : 2738)	θ value	5.27518 (rank : 2378)
Query Neighborhood Hits	2923	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CYR6, Q543F9	Gene names	Pgm3, Agm1, Pgm-3
Domain Architecture
Description	Phosphoacetylglucosamine mutase (EC 5.4.2.3) (PAGM) (Acetylglucosamine phosphomutase) (N-acetylglucosamine-phosphate mutase) (Phosphoglucomutase 3).

RBPMS_HUMAN
NC score	0.002584 (rank : 2739)	θ value	5.27518 (rank : 2497)
Query Neighborhood Hits	2923	Target Neighborhood Hits	43	Shared Neighborhood Hits	5
SwissProt Accessions	Q93062, Q92516, Q92517, Q92518, Q96J26	Gene names	RBPMS
Domain Architecture
Description	RNA-binding protein with multiple splicing (RBP-MS).

ELK4_MOUSE
NC score	0.002570 (rank : 2740)	θ value	3.0926 (rank : 2162)
Query Neighborhood Hits	2923	Target Neighborhood Hits	107	Shared Neighborhood Hits	38
SwissProt Accessions	P41158	Gene names	Elk4, Sap1
Domain Architecture
Description	ETS domain-containing protein Elk-4 (Serum response factor accessory protein 1) (SAP-1).

NUFP2_HUMAN
NC score	0.002563 (rank : 2741)	θ value	8.99809 (rank : 2845)
Query Neighborhood Hits	2923	Target Neighborhood Hits	62	Shared Neighborhood Hits	17
SwissProt Accessions	Q7Z417, Q9P2M5	Gene names	NUFIP2, KIAA1321, PIG1
Domain Architecture	No domain graphic available
Description	Nuclear fragile X mental retardation-interacting protein 2 (FMRP- interacting protein 2) (82 kDa FMRP-interacting protein) (82-FIP) (Proliferation-inducing gene 1 protein).

ITPR1_HUMAN
NC score	0.002551 (rank : 2742)	θ value	4.03905 (rank : 2297)
Query Neighborhood Hits	2923	Target Neighborhood Hits	90	Shared Neighborhood Hits	33
SwissProt Accessions	Q14643, Q14660, Q99897	Gene names	ITPR1, INSP3R1
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 1 (Type 1 inositol 1,4,5- trisphosphate receptor) (Type 1 InsP3 receptor) (IP3 receptor isoform 1) (InsP3R1) (IP3R).

DOCK3_HUMAN
NC score	0.002539 (rank : 2743)	θ value	3.0926 (rank : 2156)
Query Neighborhood Hits	2923	Target Neighborhood Hits	87	Shared Neighborhood Hits	32
SwissProt Accessions	Q8IZD9, O15017	Gene names	DOCK3, KIAA0299, MOCA
Domain Architecture
Description	Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP protein).

PRPF3_MOUSE
NC score	0.002483 (rank : 2744)	θ value	8.99809 (rank : 2860)
Query Neighborhood Hits	2923	Target Neighborhood Hits	74	Shared Neighborhood Hits	29
SwissProt Accessions	Q922U1, Q3TJH4, Q9D6C6	Gene names	Prpf3
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3).

IDS_HUMAN
NC score	0.002474 (rank : 2745)	θ value	1.06291 (rank : 1786)
Query Neighborhood Hits	2923	Target Neighborhood Hits	30	Shared Neighborhood Hits	5
SwissProt Accessions	P22304, Q14604	Gene names	IDS
Domain Architecture
Description	Iduronate 2-sulfatase precursor (EC 3.1.6.13) (Alpha-L-iduronate sulfate sulfatase) (Idursulfase) [Contains: Iduronate 2-sulfatase 42 kDa chain; Iduronate 2-sulfatase 14 kDa chain].

GRIPE_MOUSE
NC score	0.002463 (rank : 2746)	θ value	5.27518 (rank : 2433)
Query Neighborhood Hits	2923	Target Neighborhood Hits	70	Shared Neighborhood Hits	25
SwissProt Accessions	Q6GYP7, Q6GYP6, Q6ZQ28, Q8BNJ5, Q8C9G8, Q8CIW4, Q9JMC4	Gene names	Garnl1, Kiaa0884, Tulip1
Domain Architecture	No domain graphic available
Description	GTPase-activating RapGAP domain-like 1 (GAP-related-interacting partner to E12) (GRIPE) (Tuberin-like protein 1).

AKAP4_HUMAN
NC score	0.002442 (rank : 2747)	θ value	2.36792 (rank : 2011)
Query Neighborhood Hits	2923	Target Neighborhood Hits	33	Shared Neighborhood Hits	9
SwissProt Accessions	Q5JQC9, O60904, O95246, Q5JQD1, Q5JQD2, Q5JQD3	Gene names	AKAP4, AKAP82
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 4 precursor (Protein kinase A-anchoring protein 4) (PRKA4) (A-kinase anchor protein 82 kDa) (AKAP 82) (hAKAP82) (Major sperm fibrous sheath protein) (HI).

PO6F1_MOUSE
NC score	0.002429 (rank : 2748)	θ value	1.06291 (rank : 1803)
Query Neighborhood Hits	2923	Target Neighborhood Hits	581	Shared Neighborhood Hits	150
SwissProt Accessions	Q07916, Q91XK3	Gene names	Pou6f1, Emb
Domain Architecture
Description	POU domain, class 6, transcription factor 1 (Octamer-binding transcription factor EMB) (Transcription regulatory protein MCP-1).

WHRN_HUMAN
NC score	0.002397 (rank : 2749)	θ value	4.03905 (rank : 2367)
Query Neighborhood Hits	2923	Target Neighborhood Hits	325	Shared Neighborhood Hits	84
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

MYCL2_HUMAN
NC score	0.002373 (rank : 2750)	θ value	1.38821 (rank : 1865)
Query Neighborhood Hits	2923	Target Neighborhood Hits	63	Shared Neighborhood Hits	11
SwissProt Accessions	P12525	Gene names	MYCL2
Domain Architecture
Description	L-myc-2 protein.

NUCL_MOUSE
NC score	0.002341 (rank : 2751)	θ value	3.0926 (rank : 2201)
Query Neighborhood Hits	2923	Target Neighborhood Hits	425	Shared Neighborhood Hits	103
SwissProt Accessions	P09405, Q548M9, Q61991, Q99K50	Gene names	Ncl, Nuc
Domain Architecture
Description	Nucleolin (Protein C23).

DLGP2_MOUSE
NC score	0.002322 (rank : 2752)	θ value	3.0926 (rank : 2155)
Query Neighborhood Hits	2923	Target Neighborhood Hits	49	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BJ42, Q6XBF3	Gene names	Dlgap2, Dap2
Domain Architecture	No domain graphic available
Description	Disks large-associated protein 2 (DAP-2) (SAP90/PSD-95-associated protein 2) (SAPAP2) (PSD-95/SAP90-binding protein 2).

TXND3_MOUSE
NC score	0.002288 (rank : 2753)	θ value	3.0926 (rank : 2231)
Query Neighborhood Hits	2923	Target Neighborhood Hits	51	Shared Neighborhood Hits	13
SwissProt Accessions	Q715T0, Q80W74	Gene names	Txndc3, Sptrx2
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 3 (Spermatid-specific thioredoxin-2) (Sptrx-2).

TTLL2_HUMAN
NC score	0.002284 (rank : 2754)	θ value	1.81305 (rank : 2002)
Query Neighborhood Hits	2923	Target Neighborhood Hits	23	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BWV7, Q7Z6R8, Q86X22	Gene names	TTLL2, C6orf104
Domain Architecture
Description	Tubulin--tyrosine ligase-like protein 2 (Testis-specific protein NYD- TSPG).

HS12A_MOUSE
NC score	0.002229 (rank : 2755)	θ value	6.88961 (rank : 2622)
Query Neighborhood Hits	2923	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K0U4, Q3UQZ8	Gene names	Hspa12a
Domain Architecture
Description	Heat shock 70 kDa protein 12A.

GA45B_MOUSE
NC score	0.002220 (rank : 2756)	θ value	3.0926 (rank : 2172)
Query Neighborhood Hits	2923	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	P22339, Q3U342, Q9R106	Gene names	Gadd45b, Myd118
Domain Architecture
Description	Growth arrest and DNA-damage-inducible protein GADD45 beta (Negative growth-regulatory protein MyD118) (Myeloid differentiation primary response protein MyD118).

VATA1_MOUSE
NC score	0.002206 (rank : 2757)	θ value	3.0926 (rank : 2236)
Query Neighborhood Hits	2923	Target Neighborhood Hits	19	Shared Neighborhood Hits	5
SwissProt Accessions	P50516	Gene names	Atp6v1a, Atp6a1, Atp6a2, Atp6v1a1
Domain Architecture
Description	Vacuolar ATP synthase catalytic subunit A, ubiquitous isoform (EC 3.6.3.14) (V-ATPase subunit A 1) (Vacuolar proton pump alpha subunit 1) (V-ATPase 69 kDa subunit 1).

ACTN2_HUMAN
NC score	0.002167 (rank : 2758)	θ value	1.81305 (rank : 1900)
Query Neighborhood Hits	2923	Target Neighborhood Hits	295	Shared Neighborhood Hits	114
SwissProt Accessions	P35609, Q86TF4, Q86TI8	Gene names	ACTN2
Domain Architecture
Description	Alpha-actinin-2 (Alpha actinin skeletal muscle isoform 2) (F-actin cross-linking protein).

VATA1_HUMAN
NC score	0.002138 (rank : 2759)	θ value	3.0926 (rank : 2235)
Query Neighborhood Hits	2923	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	P38606, Q96DY6, Q9UHY3	Gene names	ATP6V1A, ATP6A1, ATP6V1A1, VPP2
Domain Architecture
Description	Vacuolar ATP synthase catalytic subunit A, ubiquitous isoform (EC 3.6.3.14) (V-ATPase subunit A 1) (Vacuolar proton pump alpha subunit 1) (V-ATPase 69 kDa subunit 1) (Isoform VA68).

KV5D_MOUSE
NC score	0.002108 (rank : 2760)	θ value	2.36792 (rank : 2073)
Query Neighborhood Hits	2923	Target Neighborhood Hits	255	Shared Neighborhood Hits	90
SwissProt Accessions	P01636	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-V region MOPC 149.

GLUD1_MOUSE
NC score	0.002070 (rank : 2761)	θ value	6.88961 (rank : 2609)
Query Neighborhood Hits	2923	Target Neighborhood Hits	23	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CIX8	Gene names	Gluld1, Lgs
Domain Architecture	No domain graphic available
Description	Glutamate--ammonia ligase domain-containing protein 1 (Lengsin) (Lens glutamine synthase-like).

AIRE_MOUSE
NC score	0.001994 (rank : 2762)	θ value	5.27518 (rank : 2382)
Query Neighborhood Hits	2923	Target Neighborhood Hits	196	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

HB2B_HUMAN
NC score	0.001991 (rank : 2763)	θ value	5.27518 (rank : 2437)
Query Neighborhood Hits	2923	Target Neighborhood Hits	209	Shared Neighborhood Hits	57
SwissProt Accessions	P01912	Gene names
Domain Architecture
Description	HLA class II histocompatibility antigen, DR-1 beta chain precursor (Clone P2-beta-3).

FOXM1_HUMAN
NC score	0.001980 (rank : 2764)	θ value	0.125558 (rank : 1387)
Query Neighborhood Hits	2923	Target Neighborhood Hits	167	Shared Neighborhood Hits	57
SwissProt Accessions	Q08050, O43258, O43259, O43260, Q4ZGG7, Q9BRL2	Gene names	FOXM1, FKHL16, HFH11, MPP2, WIN
Domain Architecture
Description	Forkhead box protein M1 (Forkhead-related protein FKHL16) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/fork-head homolog 11) (HFH-11) (Winged helix factor from INS-1 cells) (M-phase phosphoprotein 2) (MPM-2 reactive phosphoprotein 2) (Transcription factor Trident).

DOCK3_MOUSE
NC score	0.001963 (rank : 2765)	θ value	6.88961 (rank : 2587)
Query Neighborhood Hits	2923	Target Neighborhood Hits	93	Shared Neighborhood Hits	33
SwissProt Accessions	Q8CIQ7	Gene names	Dock3, Moca
Domain Architecture
Description	Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP protein).

AKA10_MOUSE
NC score	0.001842 (rank : 2766)	θ value	8.99809 (rank : 2727)
Query Neighborhood Hits	2923	Target Neighborhood Hits	75	Shared Neighborhood Hits	19
SwissProt Accessions	O88845, Q5SUB5, Q5SUB7, Q7TPE7, Q8BQL6	Gene names	Akap10
Domain Architecture	No domain graphic available
Description	A kinase anchor protein 10, mitochondrial precursor (Protein kinase A- anchoring protein 10) (PRKA10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2).

CELR2_HUMAN
NC score	0.001772 (rank : 2767)	θ value	8.99809 (rank : 2747)
Query Neighborhood Hits	2923	Target Neighborhood Hits	657	Shared Neighborhood Hits	118
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

C1QBP_HUMAN
NC score	0.001752 (rank : 2768)	θ value	8.99809 (rank : 2740)
Query Neighborhood Hits	2923	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	Q07021, Q2HXR8, Q9NNY8	Gene names	C1QBP, GC1QBP, HABP1, SF2P32
Domain Architecture
Description	Complement component 1 Q subcomponent-binding protein, mitochondrial precursor (Glycoprotein gC1qBP) (C1qBP) (GC1q-R protein) (Hyaluronan- binding protein 1) (Mitochondrial matrix protein p32) (p33).

VPP4_HUMAN
NC score	0.001745 (rank : 2769)	θ value	5.27518 (rank : 2529)
Query Neighborhood Hits	2923	Target Neighborhood Hits	34	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HBG4	Gene names	ATP6V0A4, ATP6N1B
Domain Architecture
Description	Vacuolar proton translocating ATPase 116 kDa subunit a isoform 4 (V- ATPase 116 kDa isoform a4) (Vacuolar proton translocating ATPase 116 kDa subunit a kidney isoform).

CN021_HUMAN
NC score	0.001698 (rank : 2770)	θ value	6.88961 (rank : 2568)
Query Neighborhood Hits	2923	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	Q86U38, Q8IVF0, Q8TBS6	Gene names	C14orf21, KIAA2021
Domain Architecture	No domain graphic available
Description	Protein C14orf21.

CCNB1_HUMAN
NC score	0.001689 (rank : 2771)	θ value	5.27518 (rank : 2395)
Query Neighborhood Hits	2923	Target Neighborhood Hits	61	Shared Neighborhood Hits	22
SwissProt Accessions	P14635	Gene names	CCNB1, CCNB
Domain Architecture
Description	G2/mitotic-specific cyclin-B1.

TTC12_MOUSE
NC score	0.001688 (rank : 2772)	θ value	0.279714 (rank : 1525)
Query Neighborhood Hits	2923	Target Neighborhood Hits	98	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BW49	Gene names	Ttc12
Domain Architecture
Description	Tetratricopeptide repeat protein 12 (TPR repeat protein 12).

SYLC_MOUSE
NC score	0.001648 (rank : 2773)	θ value	4.03905 (rank : 2360)
Query Neighborhood Hits	2923	Target Neighborhood Hits	25	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BMJ2, Q8BKW9	Gene names	Lars
Domain Architecture
Description	Leucyl-tRNA synthetase, cytoplasmic (EC 6.1.1.4) (Leucine--tRNA ligase) (LeuRS).

TMEPA_MOUSE
NC score	0.001641 (rank : 2774)	θ value	6.88961 (rank : 2702)
Query Neighborhood Hits	2923	Target Neighborhood Hits	46	Shared Neighborhood Hits	17
SwissProt Accessions	Q9D7R2, Q9EQH9	Gene names	Tmepai, N4wbp4
Domain Architecture	No domain graphic available
Description	Transmembrane prostate androgen-induced protein (NEDD4 WW domain- binding protein 4).

CNGA2_MOUSE
NC score	0.001602 (rank : 2775)	θ value	4.03905 (rank : 2265)
Query Neighborhood Hits	2923	Target Neighborhood Hits	86	Shared Neighborhood Hits	35
SwissProt Accessions	Q62398	Gene names	Cnga2, Cncg2, Cncg4
Domain Architecture
Description	Cyclic nucleotide-gated olfactory channel (Cyclic nucleotide-gated cation channel 2) (CNG channel 2) (CNG-2) (CNG2).

ABEC4_MOUSE
NC score	0.001568 (rank : 2776)	θ value	8.99809 (rank : 2721)
Query Neighborhood Hits	2923	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	Q497M3	Gene names	Apobec4
Domain Architecture	No domain graphic available
Description	Putative C->U-editing enzyme APOBEC-4 (EC 3.5.4.-) (Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 4).

ETV5_MOUSE
NC score	0.001564 (rank : 2777)	θ value	1.81305 (rank : 1934)
Query Neighborhood Hits	2923	Target Neighborhood Hits	328	Shared Neighborhood Hits	99
SwissProt Accessions	Q9CXC9, Q3TG49, Q8C0F3, Q9JHB1	Gene names	Etv5
Domain Architecture	No domain graphic available
Description	ETS translocation variant 5.

UBR1_MOUSE
NC score	0.001544 (rank : 2778)	θ value	5.27518 (rank : 2528)
Query Neighborhood Hits	2923	Target Neighborhood Hits	52	Shared Neighborhood Hits	9
SwissProt Accessions	O70481, Q5BKR8, Q792M3, Q8BN40, Q8C5K3	Gene names	Ubr1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3 component N-recognin-1 (EC 6.-.-.-) (Ubiquitin-protein ligase E3-alpha-1) (Ubiquitin-protein ligase E3- alpha-I).

AKA10_HUMAN
NC score	0.001532 (rank : 2779)	θ value	8.99809 (rank : 2726)
Query Neighborhood Hits	2923	Target Neighborhood Hits	58	Shared Neighborhood Hits	10
SwissProt Accessions	O43572, Q96AJ7	Gene names	AKAP10
Domain Architecture
Description	A kinase anchor protein 10, mitochondrial precursor (Protein kinase A- anchoring protein 10) (PRKA10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2).

BBX_HUMAN
NC score	0.001467 (rank : 2780)	θ value	5.27518 (rank : 2389)
Query Neighborhood Hits	2923	Target Neighborhood Hits	167	Shared Neighborhood Hits	65
SwissProt Accessions	Q8WY36, Q2TAJ1, Q7L3J8, Q7LBY8, Q8NDB0, Q8WY35, Q9H0J6	Gene names	BBX, HBP2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

MYST1_HUMAN
NC score	0.001466 (rank : 2781)	θ value	8.99809 (rank : 2840)
Query Neighborhood Hits	2923	Target Neighborhood Hits	53	Shared Neighborhood Hits	33
SwissProt Accessions	Q9H7Z6, Q659G0, Q7LC17, Q8IY59, Q8WYB4, Q8WZ14, Q9HAC5, Q9NR35	Gene names	MYST1, MOF
Domain Architecture	No domain graphic available
Description	Probable histone acetyltransferase MYST1 (EC 2.3.1.48) (MYST protein 1) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1) (hMOF).

SMP1L_HUMAN
NC score	0.001457 (rank : 2782)	θ value	0.47712 (rank : 1632)
Query Neighborhood Hits	2923	Target Neighborhood Hits	74	Shared Neighborhood Hits	24
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

MYST1_MOUSE
NC score	0.001431 (rank : 2783)	θ value	8.99809 (rank : 2841)
Query Neighborhood Hits	2923	Target Neighborhood Hits	57	Shared Neighborhood Hits	34
SwissProt Accessions	Q9D1P2, Q3UIY0, Q8BJ69, Q8BJ76, Q8CI73	Gene names	Myst1, Mof
Domain Architecture	No domain graphic available
Description	Probable histone acetyltransferase MYST1 (EC 2.3.1.48) (MYST protein 1) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1).

DYXC1_MOUSE
NC score	0.001427 (rank : 2784)	θ value	5.27518 (rank : 2416)
Query Neighborhood Hits	2923	Target Neighborhood Hits	172	Shared Neighborhood Hits	73
SwissProt Accessions	Q8R368	Gene names	Dyx1c1, Ekn1
Domain Architecture
Description	Dyslexia susceptibility 1 candidate gene 1 protein homolog.

LV4E_HUMAN
NC score	0.001410 (rank : 2785)	θ value	1.81305 (rank : 1956)
Query Neighborhood Hits	2923	Target Neighborhood Hits	218	Shared Neighborhood Hits	72
SwissProt Accessions	P06889	Gene names
Domain Architecture	No domain graphic available
Description	Ig lambda chain V-IV region MOL.

DVL2_MOUSE
NC score	0.001347 (rank : 2786)	θ value	1.06291 (rank : 1776)
Query Neighborhood Hits	2923	Target Neighborhood Hits	233	Shared Neighborhood Hits	61
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

ZHX2_MOUSE
NC score	0.001347 (rank : 2787)	θ value	0.47712 (rank : 1645)
Query Neighborhood Hits	2923	Target Neighborhood Hits	435	Shared Neighborhood Hits	74
SwissProt Accessions	Q8C0C0	Gene names	Zhx2, Afr1, Raf
Domain Architecture
Description	Zinc fingers and homeoboxes protein 2 (Zinc finger and homeodomain protein 2) (Alpha-fetoprotein regulator 1) (AFP regulator 1) (Regulator of AFP).

TECT3_MOUSE
NC score	0.001331 (rank : 2788)	θ value	8.99809 (rank : 2897)
Query Neighborhood Hits	2923	Target Neighborhood Hits	33	Shared Neighborhood Hits	12
SwissProt Accessions	Q8R2Q6, Q8CDF3, Q9CRC5	Gene names	Tect3
Domain Architecture	No domain graphic available
Description	Tectonic-3 precursor.

NOL4_MOUSE
NC score	0.001287 (rank : 2789)	θ value	6.88961 (rank : 2660)
Query Neighborhood Hits	2923	Target Neighborhood Hits	44	Shared Neighborhood Hits	13
SwissProt Accessions	P60954	Gene names	Nol4
Domain Architecture	No domain graphic available
Description	Nucleolar protein 4.

DVL2_HUMAN
NC score	0.001281 (rank : 2790)	θ value	0.62314 (rank : 1661)
Query Neighborhood Hits	2923	Target Neighborhood Hits	223	Shared Neighborhood Hits	53
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

GPI8_MOUSE
NC score	0.001266 (rank : 2791)	θ value	8.99809 (rank : 2789)
Query Neighborhood Hits	2923	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CXY9, Q8BH63	Gene names	Pigk
Domain Architecture
Description	GPI-anchor transamidase precursor (EC 3.-.-.-) (GPI transamidase) (Phosphatidylinositol-glycan biosynthesis class K protein) (PIG-K).

HSP72_HUMAN
NC score	0.001246 (rank : 2792)	θ value	8.99809 (rank : 2797)
Query Neighborhood Hits	2923	Target Neighborhood Hits	85	Shared Neighborhood Hits	39
SwissProt Accessions	P54652, Q15508, Q9UE78	Gene names	HSPA2
Domain Architecture
Description	Heat shock-related 70 kDa protein 2 (Heat shock 70 kDa protein 2).

ACTN2_MOUSE
NC score	0.001241 (rank : 2793)	θ value	1.81305 (rank : 1901)
Query Neighborhood Hits	2923	Target Neighborhood Hits	287	Shared Neighborhood Hits	111
SwissProt Accessions	Q9JI91	Gene names	Actn2
Domain Architecture
Description	Alpha-actinin-2 (Alpha actinin skeletal muscle isoform 2) (F-actin cross-linking protein).

ATTY_MOUSE
NC score	0.001188 (rank : 2794)	θ value	4.03905 (rank : 2254)
Query Neighborhood Hits	2923	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q8QZR1, Q3UER7, Q8BTI1	Gene names	Tat
Domain Architecture
Description	Tyrosine aminotransferase (EC 2.6.1.5) (L-tyrosine:2-oxoglutarate aminotransferase) (TAT).

MDM4_MOUSE
NC score	0.001178 (rank : 2795)	θ value	5.27518 (rank : 2463)
Query Neighborhood Hits	2923	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	O35618	Gene names	Mdm4, Mdmx
Domain Architecture
Description	Mdm4 protein (p53-binding protein Mdm4) (Mdm2-like p53-binding protein) (Mdmx protein) (Double minute 4 protein).

RAE1_MOUSE
NC score	0.001109 (rank : 2796)	θ value	8.99809 (rank : 2864)
Query Neighborhood Hits	2923	Target Neighborhood Hits	32	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QXG2, Q80UV8	Gene names	Chm, Rep1
Domain Architecture
Description	Rab proteins geranylgeranyltransferase component A 1 (Rab escort protein 1) (REP-1) (Choroideraemia protein homolog).

RHG05_MOUSE
NC score	0.001097 (rank : 2797)	θ value	6.88961 (rank : 2684)
Query Neighborhood Hits	2923	Target Neighborhood Hits	165	Shared Neighborhood Hits	56
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

HS12A_HUMAN
NC score	0.001075 (rank : 2798)	θ value	6.88961 (rank : 2621)
Query Neighborhood Hits	2923	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	O43301	Gene names	HSPA12A, KIAA0417
Domain Architecture
Description	Heat shock 70 kDa protein 12A.

SYEP_HUMAN
NC score	0.001035 (rank : 2799)	θ value	6.88961 (rank : 2696)
Query Neighborhood Hits	2923	Target Neighborhood Hits	70	Shared Neighborhood Hits	26
SwissProt Accessions	P07814	Gene names	EPRS, GLNS, PARS, QPRS
Domain Architecture
Description	Bifunctional aminoacyl-tRNA synthetase [Includes: Glutamyl-tRNA synthetase (EC 6.1.1.17) (Glutamate--tRNA ligase); Prolyl-tRNA synthetase (EC 6.1.1.15) (Proline--tRNA ligase)].

ENP6_HUMAN
NC score	0.001021 (rank : 2800)	θ value	3.0926 (rank : 2163)
Query Neighborhood Hits	2923	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	O75354, Q7Z5B5, Q8TAS7, Q9UJD1	Gene names	ENTPD6, CD39L2
Domain Architecture
Description	Ectonucleoside triphosphate diphosphohydrolase 6 (EC 3.6.1.6) (NTPDase 6) (CD39 antigen-like 2).

2B1B_HUMAN
NC score	0.001013 (rank : 2801)	θ value	5.27518 (rank : 2372)
Query Neighborhood Hits	2923	Target Neighborhood Hits	208	Shared Neighborhood Hits	56
SwissProt Accessions	P20039, Q30006, Q9GIX8	Gene names	HLA-DRB1
Domain Architecture
Description	HLA class II histocompatibility antigen, DRB1-11 beta chain precursor (MHC class I antigen DRB1*11) (DR-5) (DR5) (DRw11).

JHD3A_HUMAN
NC score	0.000973 (rank : 2802)	θ value	8.99809 (rank : 2804)
Query Neighborhood Hits	2923	Target Neighborhood Hits	78	Shared Neighborhood Hits	23
SwissProt Accessions	O75164, Q5VVB1	Gene names	JMJD2A, JHDM3A, JMJD2, KIAA0677
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3A (EC 1.14.11.-) (Jumonji domain-containing protein 2A).

KV5B_MOUSE
NC score	0.000960 (rank : 2803)	θ value	4.03905 (rank : 2304)
Query Neighborhood Hits	2923	Target Neighborhood Hits	253	Shared Neighborhood Hits	87
SwissProt Accessions	P01634	Gene names
Domain Architecture
Description	Ig kappa chain V-V region MOPC 21 precursor.

SMCA1_HUMAN
NC score	0.000959 (rank : 2804)	θ value	8.99809 (rank : 2881)
Query Neighborhood Hits	2923	Target Neighborhood Hits	105	Shared Neighborhood Hits	41
SwissProt Accessions	P28370, Q5JV41, Q5JV42	Gene names	SMARCA1, SNF2L, SNF2L1
Domain Architecture
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1).

TCPE_HUMAN
NC score	0.000941 (rank : 2805)	θ value	0.279714 (rank : 1524)
Query Neighborhood Hits	2923	Target Neighborhood Hits	39	Shared Neighborhood Hits	7
SwissProt Accessions	P48643	Gene names	CCT5, CCTE, KIAA0098
Domain Architecture
Description	T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon).

LV3A_HUMAN
NC score	0.000933 (rank : 2806)	θ value	0.813845 (rank : 1734)
Query Neighborhood Hits	2923	Target Neighborhood Hits	238	Shared Neighborhood Hits	69
SwissProt Accessions	P01714	Gene names
Domain Architecture	No domain graphic available
Description	Ig lambda chain V-III region SH.

2DOB_HUMAN
NC score	0.000925 (rank : 2807)	θ value	0.47712 (rank : 1580)
Query Neighborhood Hits	2923	Target Neighborhood Hits	201	Shared Neighborhood Hits	48
SwissProt Accessions	P13765, Q29746, Q29825	Gene names	HLA-DOB
Domain Architecture
Description	HLA class II histocompatibility antigen, DO beta chain precursor (MHC class II antigen DOB).

KV1Q_HUMAN
NC score	0.000924 (rank : 2808)	θ value	3.0926 (rank : 2182)
Query Neighborhood Hits	2923	Target Neighborhood Hits	197	Shared Neighborhood Hits	78
SwissProt Accessions	P01609	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-I region Scw.

2B18_HUMAN
NC score	0.000890 (rank : 2809)	θ value	5.27518 (rank : 2371)
Query Neighborhood Hits	2923	Target Neighborhood Hits	210	Shared Neighborhood Hits	56
SwissProt Accessions	Q30134, O19718, O19788, Q29968, Q30108, Q30115, Q9BCP0, Q9BCP1, Q9BCP2, Q9BD33, Q9TQ37, Q9UIM9	Gene names	HLA-DRB1
Domain Architecture
Description	HLA class II histocompatibility antigen, DRB1-8 beta chain precursor (MHC class I antigen DRB1*8) (DR-8) (DR8) (DRw8).

TSH1_MOUSE
NC score	0.000882 (rank : 2810)	θ value	0.813845 (rank : 1757)
Query Neighborhood Hits	2923	Target Neighborhood Hits	675	Shared Neighborhood Hits	119
SwissProt Accessions	Q5DTH5, Q6PE60, Q8VD19, Q9JLD5	Gene names	Tshz1, Kiaa4206, Sdccag33, Tsh1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3 homolog).

KV5E_MOUSE
NC score	0.000865 (rank : 2811)	θ value	5.27518 (rank : 2450)
Query Neighborhood Hits	2923	Target Neighborhood Hits	249	Shared Neighborhood Hits	89
SwissProt Accessions	P01637	Gene names
Domain Architecture
Description	Ig kappa chain V-V region T1 precursor.

CELR2_MOUSE
NC score	0.000801 (rank : 2812)	θ value	6.88961 (rank : 2562)
Query Neighborhood Hits	2923	Target Neighborhood Hits	584	Shared Neighborhood Hits	109
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

MCCA_HUMAN
NC score	0.000789 (rank : 2813)	θ value	1.38821 (rank : 1864)
Query Neighborhood Hits	2923	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	Q96RQ3, Q59ES4, Q9H959, Q9NS97	Gene names	MCCC1, MCCA
Domain Architecture
Description	Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial precursor (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 1) (MCCase subunit alpha) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha) (3- methylcrotonyl-CoA carboxylase biotin-containing subunit).

BORG3_MOUSE
NC score	0.000786 (rank : 2814)	θ value	8.99809 (rank : 2738)
Query Neighborhood Hits	2923	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z0X0, Q3SYK1, Q9QZT9	Gene names	Cdc42ep5, Borg3, Cep5
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 5 (Binder of Rho GTPases 3).

FOXP1_MOUSE
NC score	0.000775 (rank : 2815)	θ value	1.06291 (rank : 1777)
Query Neighborhood Hits	2923	Target Neighborhood Hits	241	Shared Neighborhood Hits	97
SwissProt Accessions	P58462	Gene names	Foxp1
Domain Architecture
Description	Forkhead box protein P1 (Forkhead-related transcription factor 1).

DAF1_MOUSE
NC score	0.000701 (rank : 2816)	θ value	0.813845 (rank : 1715)
Query Neighborhood Hits	2923	Target Neighborhood Hits	204	Shared Neighborhood Hits	68
SwissProt Accessions	Q61475, P97732, Q61397	Gene names	Cd55a, Daf1
Domain Architecture
Description	Complement decay-accelerating factor, GPI-anchored precursor (DAF-GPI) (CD55 antigen).

IDS_MOUSE
NC score	0.000666 (rank : 2817)	θ value	4.03905 (rank : 2294)
Query Neighborhood Hits	2923	Target Neighborhood Hits	36	Shared Neighborhood Hits	6
SwissProt Accessions	Q08890, Q3TM30	Gene names	Ids
Domain Architecture
Description	Iduronate 2-sulfatase precursor (EC 3.1.6.13) (Alpha-L-iduronate sulfate sulfatase).

DJC12_HUMAN
NC score	0.000646 (rank : 2818)	θ value	8.99809 (rank : 2766)
Query Neighborhood Hits	2923	Target Neighborhood Hits	141	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UKB3, Q9UKB2	Gene names	DNAJC12, JDP1
Domain Architecture
Description	DnaJ homolog subfamily C member 12 (J domain-containing protein 1).

ANR44_HUMAN
NC score	0.000638 (rank : 2819)	θ value	8.99809 (rank : 2729)
Query Neighborhood Hits	2923	Target Neighborhood Hits	318	Shared Neighborhood Hits	46
SwissProt Accessions	Q8N8A2, Q6P480, Q86VL5, Q8IZ72, Q9UFA4	Gene names	ANKRD44
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 44.

TVA3_MOUSE
NC score	0.000620 (rank : 2820)	θ value	1.81305 (rank : 2003)
Query Neighborhood Hits	2923	Target Neighborhood Hits	192	Shared Neighborhood Hits	59
SwissProt Accessions	P06323	Gene names
Domain Architecture	No domain graphic available
Description	T-cell receptor alpha chain V region CTL-F3 precursor.

PTD4_HUMAN
NC score	0.000587 (rank : 2821)	θ value	8.99809 (rank : 2861)
Query Neighborhood Hits	2923	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NTK5, Q8NCI8, Q96CU1, Q96SV2, Q9P1D3, Q9UNY9, Q9Y6G4	Gene names	ames=PTD004, PRO2455
Domain Architecture
Description	Putative GTP-binding protein PTD004.

NCOA2_HUMAN
NC score	0.000555 (rank : 2822)	θ value	4.03905 (rank : 2323)
Query Neighborhood Hits	2923	Target Neighborhood Hits	281	Shared Neighborhood Hits	73
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

R113B_HUMAN
NC score	0.000547 (rank : 2823)	θ value	2.36792 (rank : 2093)
Query Neighborhood Hits	2923	Target Neighborhood Hits	165	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

FYV1_HUMAN
NC score	0.000441 (rank : 2824)	θ value	6.88961 (rank : 2604)
Query Neighborhood Hits	2923	Target Neighborhood Hits	217	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

LV4D_HUMAN
NC score	0.000439 (rank : 2825)	θ value	3.0926 (rank : 2188)
Query Neighborhood Hits	2923	Target Neighborhood Hits	199	Shared Neighborhood Hits	69
SwissProt Accessions	P01718	Gene names
Domain Architecture	No domain graphic available
Description	Ig lambda chain V-IV region Kern.

TMEPA_HUMAN
NC score	0.000411 (rank : 2826)	θ value	8.99809 (rank : 2900)
Query Neighborhood Hits	2923	Target Neighborhood Hits	46	Shared Neighborhood Hits	15
SwissProt Accessions	Q969W9, Q5TDR6, Q96B72, Q9UJD3	Gene names	TMEPAI, PMEPA1, STAG1
Domain Architecture
Description	Transmembrane prostate androgen-induced protein (Solid tumor- associated 1 protein).

PA2G4_HUMAN
NC score	0.000407 (rank : 2827)	θ value	8.99809 (rank : 2848)
Query Neighborhood Hits	2923	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UQ80, O43846, Q9UM59	Gene names	PA2G4, EBP1
Domain Architecture
Description	Proliferation-associated protein 2G4 (Cell cycle protein p38-2G4 homolog) (hG4-1) (ErbB3-binding protein 1).

HINT2_HUMAN
NC score	0.000382 (rank : 2828)	θ value	8.99809 (rank : 2795)
Query Neighborhood Hits	2923	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BX68	Gene names	HINT2
Domain Architecture	No domain graphic available
Description	Histidine triad nucleotide-binding protein 2 (EC 3.-.-.-) (HINT-2) (HINT-3) (HIT-17kDa) (PKCI-1-related HIT protein).

KV3K_HUMAN
NC score	0.000360 (rank : 2829)	θ value	2.36792 (rank : 2072)
Query Neighborhood Hits	2923	Target Neighborhood Hits	279	Shared Neighborhood Hits	84
SwissProt Accessions	P06311	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-III region IARC/BL41 precursor.

DHX57_MOUSE
NC score	0.000316 (rank : 2830)	θ value	0.813845 (rank : 1716)
Query Neighborhood Hits	2923	Target Neighborhood Hits	125	Shared Neighborhood Hits	28
SwissProt Accessions	Q6P5D3, Q3TS93, Q6NZK4, Q6P1B4, Q8BI63, Q8BIA2, Q8R360	Gene names	Dhx57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

PDIA1_MOUSE
NC score	0.000298 (rank : 2831)	θ value	5.27518 (rank : 2489)
Query Neighborhood Hits	2923	Target Neighborhood Hits	50	Shared Neighborhood Hits	8
SwissProt Accessions	P09103	Gene names	P4hb, Pdia1
Domain Architecture
Description	Protein disulfide-isomerase precursor (EC 5.3.4.1) (PDI) (Prolyl 4- hydroxylase subunit beta) (Cellular thyroid hormone-binding protein) (p55) (Erp59).

ACO12_HUMAN
NC score	0.000258 (rank : 2832)	θ value	4.03905 (rank : 2247)
Query Neighborhood Hits	2923	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WYK0	Gene names	ACOT12, CACH, CACH1, STARD12
Domain Architecture
Description	Acyl-coenzyme A thioesterase 12 (EC 3.1.2.1) (Acyl-CoA thioesterase 12) (Acyl-CoA thioester hydrolase 12) (Cytoplasmic acetyl-CoA hydrolase 1) (CACH-1) (hCACH-1) (START domain-containing protein 12) (StARD12).

CCS_HUMAN
NC score	0.000230 (rank : 2833)	θ value	6.88961 (rank : 2560)
Query Neighborhood Hits	2923	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	O14618	Gene names	CCS
Domain Architecture
Description	Copper chaperone for superoxide dismutase (Superoxide dismutase copper chaperone).

LV4B_HUMAN
NC score	0.000208 (rank : 2834)	θ value	4.03905 (rank : 2311)
Query Neighborhood Hits	2923	Target Neighborhood Hits	202	Shared Neighborhood Hits	70
SwissProt Accessions	P01716	Gene names
Domain Architecture	No domain graphic available
Description	Ig lambda chain V-IV region X.

GP149_HUMAN
NC score	0.000148 (rank : 2835)	θ value	6.88961 (rank : 2612)
Query Neighborhood Hits	2923	Target Neighborhood Hits	68	Shared Neighborhood Hits	8
SwissProt Accessions	Q86SP6	Gene names	GPR149, PGR10
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 149 (G-protein coupled receptor PGR10).

AIP_HUMAN
NC score	0.000132 (rank : 2836)	θ value	5.27518 (rank : 2381)
Query Neighborhood Hits	2923	Target Neighborhood Hits	51	Shared Neighborhood Hits	9
SwissProt Accessions	O00170, Q99606	Gene names	AIP, XAP2
Domain Architecture
Description	AH receptor-interacting protein (AIP) (Aryl-hydrocarbon receptor- interacting protein) (Immunophilin homolog ARA9) (HBV-X-associated protein 2).

HB2X_HUMAN
NC score	0.000031 (rank : 2837)	θ value	8.99809 (rank : 2792)
Query Neighborhood Hits	2923	Target Neighborhood Hits	209	Shared Neighborhood Hits	56
SwissProt Accessions	P05538, Q29870, Q29871, Q29872, Q29873	Gene names	HLA-DQB2
Domain Architecture	No domain graphic available
Description	HLA class II histocompatibility antigen, DX beta chain precursor.

PITM2_HUMAN
NC score	0.000001 (rank : 2838)	θ value	4.03905 (rank : 2333)
Query Neighborhood Hits	2923	Target Neighborhood Hits	52	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BZ72, Q9P271	Gene names	PITPNM2, KIAA1457, NIR3
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 2 (Phosphatidylinositol transfer protein, membrane-associated 2) (Pyk2 N-terminal domain-interacting receptor 3) (NIR-3).

RNF37_HUMAN
NC score	-0.000016 (rank : 2839)	θ value	8.99809 (rank : 2869)
Query Neighborhood Hits	2923	Target Neighborhood Hits	82	Shared Neighborhood Hits	14
SwissProt Accessions	O94941	Gene names	UBOX5, KIAA0860, RNF37, UBCE7IP5
Domain Architecture
Description	RING finger protein 37 (Ubiquitin-conjugating enzyme 7-interacting protein 5) (U-box domain-containing protein 5).

CASP5_HUMAN
NC score	-0.000045 (rank : 2840)	θ value	3.0926 (rank : 2139)
Query Neighborhood Hits	2923	Target Neighborhood Hits	28	Shared Neighborhood Hits	5
SwissProt Accessions	P51878	Gene names	CASP5, ICH3
Domain Architecture
Description	Caspase-5 precursor (EC 3.4.22.-) (CASP-5) (ICH-3 protease) (TY protease) (ICE(rel)-III) [Contains: Caspase-5 subunit p20; Caspase-5 subunit p10].

TCPE_MOUSE
NC score	-0.000066 (rank : 2841)	θ value	0.813845 (rank : 1752)
Query Neighborhood Hits	2923	Target Neighborhood Hits	37	Shared Neighborhood Hits	7
SwissProt Accessions	P80316	Gene names	Cct5, Ccte
Domain Architecture
Description	T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon).

XKR6_HUMAN
NC score	-0.000096 (rank : 2842)	θ value	3.0926 (rank : 2241)
Query Neighborhood Hits	2923	Target Neighborhood Hits	43	Shared Neighborhood Hits	6
SwissProt Accessions	Q5GH73, Q8TBA0	Gene names	XKR6, C8orf21, C8orf7, XRG6
Domain Architecture	No domain graphic available
Description	XK-related protein 6.

DHX40_MOUSE
NC score	-0.000105 (rank : 2843)	θ value	2.36792 (rank : 2040)
Query Neighborhood Hits	2923	Target Neighborhood Hits	40	Shared Neighborhood Hits	15
SwissProt Accessions	Q6PE54, Q8BPH2, Q8CD88, Q9CWN3	Gene names	Dhx40
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX40 (EC 3.6.1.-) (DEAH box protein 40).

CAC1H_MOUSE
NC score	-0.000111 (rank : 2844)	θ value	5.27518 (rank : 2394)
Query Neighborhood Hits	2923	Target Neighborhood Hits	230	Shared Neighborhood Hits	66
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

ARRD2_HUMAN
NC score	-0.000161 (rank : 2845)	θ value	4.03905 (rank : 2250)
Query Neighborhood Hits	2923	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TBH0, O95895, Q6ZRV9, Q8WYG6	Gene names	ARRDC2
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 2.

PDIA4_MOUSE
NC score	-0.000178 (rank : 2846)	θ value	5.27518 (rank : 2490)
Query Neighborhood Hits	2923	Target Neighborhood Hits	57	Shared Neighborhood Hits	9
SwissProt Accessions	P08003, P15841	Gene names	Pdia4, Cai, Erp72
Domain Architecture
Description	Protein disulfide-isomerase A4 precursor (EC 5.3.4.1) (Protein ERp-72) (ERp72).

KV3H_HUMAN
NC score	-0.000184 (rank : 2847)	θ value	4.03905 (rank : 2300)
Query Neighborhood Hits	2923	Target Neighborhood Hits	285	Shared Neighborhood Hits	82
SwissProt Accessions	P04207	Gene names
Domain Architecture
Description	Ig kappa chain V-III region CLL precursor (Rheumatoid factor).

ATCAY_HUMAN
NC score	-0.000227 (rank : 2848)	θ value	4.03905 (rank : 2252)
Query Neighborhood Hits	2923	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	Q86WG3, Q8NAQ2, Q8TAQ3, Q96HC6, Q96JF5	Gene names	ATCAY, KIAA1872
Domain Architecture
Description	Caytaxin (Ataxia Cayman type protein) (BNIP-H).

DHX40_HUMAN
NC score	-0.000260 (rank : 2849)	θ value	2.36792 (rank : 2039)
Query Neighborhood Hits	2923	Target Neighborhood Hits	34	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IX18, Q5JPH4, Q8TC86, Q8WY53, Q9BXM1, Q9H6M9	Gene names	DHX40, DDX40
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX40 (EC 3.6.1.-) (DEAH box protein 40) (ARG147) (Protein PAD).

AMD_HUMAN
NC score	-0.000261 (rank : 2850)	θ value	8.99809 (rank : 2728)
Query Neighborhood Hits	2923	Target Neighborhood Hits	22	Shared Neighborhood Hits	6
SwissProt Accessions	P19021, O95080, Q16252, Q16253, Q86U53, Q8WVC7, Q9UCG0	Gene names	PAM
Domain Architecture
Description	Peptidyl-glycine alpha-amidating monooxygenase precursor (PAM) [Includes: Peptidylglycine alpha-hydroxylating monooxygenase (EC 1.14.17.3) (PHM); Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (EC 4.3.2.5) (Peptidylamidoglycolate lyase) (PAL)].

KV1C_HUMAN
NC score	-0.000298 (rank : 2851)	θ value	0.0736092 (rank : 1344)
Query Neighborhood Hits	2923	Target Neighborhood Hits	257	Shared Neighborhood Hits	80
SwissProt Accessions	P01595	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-I region Bi.

NLGN2_HUMAN
NC score	-0.000315 (rank : 2852)	θ value	4.03905 (rank : 2325)
Query Neighborhood Hits	2923	Target Neighborhood Hits	55	Shared Neighborhood Hits	18
SwissProt Accessions	Q8NFZ4, Q9P2I1	Gene names	NLGN2, KIAA1366
Domain Architecture
Description	Neuroligin-2 precursor.

SENP2_HUMAN
NC score	-0.000333 (rank : 2853)	θ value	6.88961 (rank : 2688)
Query Neighborhood Hits	2923	Target Neighborhood Hits	19	Shared Neighborhood Hits	6
SwissProt Accessions	Q9HC62, Q96SR2, Q9P2L5	Gene names	SENP2, KIAA1331
Domain Architecture
Description	Sentrin-specific protease 2 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP2) (SMT3-specific isopeptidase 2) (Smt3ip2) (Axam2).

DDX21_HUMAN
NC score	-0.000422 (rank : 2854)	θ value	5.27518 (rank : 2406)
Query Neighborhood Hits	2923	Target Neighborhood Hits	308	Shared Neighborhood Hits	133
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

U5S1_MOUSE
NC score	-0.000486 (rank : 2855)	θ value	8.99809 (rank : 2909)
Query Neighborhood Hits	2923	Target Neighborhood Hits	37	Shared Neighborhood Hits	7
SwissProt Accessions	O08810	Gene names	Eftud2, Snrp116
Domain Architecture
Description	116 kDa U5 small nuclear ribonucleoprotein component (U5 snRNP- specific protein, 116 kDa) (U5-116 kDa) (Elongation factor Tu GTP- binding domain protein 2).

PDIA1_HUMAN
NC score	-0.000496 (rank : 2856)	θ value	8.99809 (rank : 2853)
Query Neighborhood Hits	2923	Target Neighborhood Hits	56	Shared Neighborhood Hits	10
SwissProt Accessions	P07237, P30037, P32079, Q15205, Q6LDE5	Gene names	P4HB, PDI, PDIA1, PO4DB
Domain Architecture
Description	Protein disulfide-isomerase precursor (EC 5.3.4.1) (PDI) (Prolyl 4- hydroxylase subunit beta) (Cellular thyroid hormone-binding protein) (p55).

NOS3_MOUSE
NC score	-0.000513 (rank : 2857)	θ value	4.03905 (rank : 2328)
Query Neighborhood Hits	2923	Target Neighborhood Hits	63	Shared Neighborhood Hits	18
SwissProt Accessions	P70313, O55056	Gene names	Nos3, Ecnos
Domain Architecture
Description	Nitric-oxide synthase, endothelial (EC 1.14.13.39) (EC-NOS) (NOS type III) (NOSIII) (Endothelial NOS) (eNOS) (Constitutive NOS) (cNOS).

NLGN2_MOUSE
NC score	-0.000526 (rank : 2858)	θ value	4.03905 (rank : 2326)
Query Neighborhood Hits	2923	Target Neighborhood Hits	49	Shared Neighborhood Hits	15
SwissProt Accessions	Q69ZK9, Q5F288	Gene names	Nlgn2, Kiaa1366
Domain Architecture	No domain graphic available
Description	Neuroligin-2 precursor.

TTLL4_HUMAN
NC score	-0.000532 (rank : 2859)	θ value	8.99809 (rank : 2905)
Query Neighborhood Hits	2923	Target Neighborhood Hits	79	Shared Neighborhood Hits	21
SwissProt Accessions	Q14679, Q8WW29	Gene names	TTLL4, KIAA0173
Domain Architecture
Description	Tubulin--tyrosine ligase-like protein 4.

U5S1_HUMAN
NC score	-0.000534 (rank : 2860)	θ value	8.99809 (rank : 2908)
Query Neighborhood Hits	2923	Target Neighborhood Hits	33	Shared Neighborhood Hits	6
SwissProt Accessions	Q15029, Q9BUR0	Gene names	EFTUD2, KIAA0031, SNRP116
Domain Architecture
Description	116 kDa U5 small nuclear ribonucleoprotein component (U5 snRNP- specific protein, 116 kDa) (U5-116 kDa) (Elongation factor Tu GTP- binding domain protein 2) (hSNU114).

NLGN3_MOUSE
NC score	-0.000538 (rank : 2861)	θ value	2.36792 (rank : 2083)
Query Neighborhood Hits	2923	Target Neighborhood Hits	48	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BYM5, Q8BXR4	Gene names	Nlgn3
Domain Architecture
Description	Neuroligin-3 precursor (Gliotactin homolog).

DP13B_MOUSE
NC score	-0.000566 (rank : 2862)	θ value	8.99809 (rank : 2769)
Query Neighborhood Hits	2923	Target Neighborhood Hits	58	Shared Neighborhood Hits	21
SwissProt Accessions	Q8K3G9, Q99LT7	Gene names	Dip13b, Appl2, Dip3b
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 beta (Dip13 beta) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 2).

ETV6_HUMAN
NC score	-0.000609 (rank : 2863)	θ value	4.03905 (rank : 2279)
Query Neighborhood Hits	2923	Target Neighborhood Hits	120	Shared Neighborhood Hits	36
SwissProt Accessions	P41212, Q9UMF6	Gene names	ETV6, TEL, TEL1
Domain Architecture
Description	Transcription factor ETV6 (ETS-related protein Tel1) (Tel) (ETS translocation variant 6).

ADAM2_MOUSE
NC score	-0.000647 (rank : 2864)	θ value	8.99809 (rank : 2723)
Query Neighborhood Hits	2923	Target Neighborhood Hits	209	Shared Neighborhood Hits	32
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

ARRD4_HUMAN
NC score	-0.000647 (rank : 2865)	θ value	6.88961 (rank : 2548)
Query Neighborhood Hits	2923	Target Neighborhood Hits	27	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NCT1, Q6NSI9	Gene names	ARRDC4
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 4.

MAGC3_HUMAN
NC score	-0.000657 (rank : 2866)	θ value	5.27518 (rank : 2458)
Query Neighborhood Hits	2923	Target Neighborhood Hits	71	Shared Neighborhood Hits	23
SwissProt Accessions	Q8TD91, Q5JZ43, Q9BZ80	Gene names	MAGEC3, HCA2
Domain Architecture
Description	Melanoma-associated antigen C3 (MAGE-C3 antigen) (Hepatocellular carcinoma-associated antigen 2).

SMBT2_MOUSE
NC score	-0.000701 (rank : 2867)	θ value	5.27518 (rank : 2515)
Query Neighborhood Hits	2923	Target Neighborhood Hits	47	Shared Neighborhood Hits	11
SwissProt Accessions	Q5DTW2, Q80VG7	Gene names	Sfmbt2, Kiaa1617
Domain Architecture	No domain graphic available
Description	Scm-like with four MBT domains protein 2.

ELF4_HUMAN
NC score	-0.000724 (rank : 2868)	θ value	8.99809 (rank : 2774)
Query Neighborhood Hits	2923	Target Neighborhood Hits	87	Shared Neighborhood Hits	29
SwissProt Accessions	Q99607, O60435	Gene names	ELF4, ELFR, MEF
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-4 (E74-like factor 4) (Myeloid Elf-1-like factor).

TBC17_HUMAN
NC score	-0.000745 (rank : 2869)	θ value	8.99809 (rank : 2896)
Query Neighborhood Hits	2923	Target Neighborhood Hits	60	Shared Neighborhood Hits	20
SwissProt Accessions	Q9HA65	Gene names	TBC1D17
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 17.

KV1G_HUMAN
NC score	-0.000800 (rank : 2870)	θ value	1.81305 (rank : 1954)
Query Neighborhood Hits	2923	Target Neighborhood Hits	241	Shared Neighborhood Hits	77
SwissProt Accessions	P01599	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-I region Gal.

DHX15_MOUSE
NC score	-0.000803 (rank : 2871)	θ value	3.0926 (rank : 2154)
Query Neighborhood Hits	2923	Target Neighborhood Hits	52	Shared Neighborhood Hits	19
SwissProt Accessions	O35286, Q99L91	Gene names	Dhx15, Ddx15, Deah9
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 (EC 3.6.1.-) (DEAH box protein 15).

K6PP_HUMAN
NC score	-0.000816 (rank : 2872)	θ value	5.27518 (rank : 2445)
Query Neighborhood Hits	2923	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q01813	Gene names	PFKP, PFKF
Domain Architecture
Description	6-phosphofructokinase type C (EC 2.7.1.11) (Phosphofructokinase 1) (Phosphohexokinase) (Phosphofructo-1-kinase isozyme C) (PFK-C) (6- phosphofructokinase, platelet type).

DHX15_HUMAN
NC score	-0.000858 (rank : 2873)	θ value	3.0926 (rank : 2153)
Query Neighborhood Hits	2923	Target Neighborhood Hits	50	Shared Neighborhood Hits	18
SwissProt Accessions	O43143, Q9NQT7	Gene names	DHX15, DBP1, DDX15
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 (EC 3.6.1.-) (DEAH box protein 15) (ATP-dependent RNA helicase #46).

HA2B_MOUSE
NC score	-0.000879 (rank : 2874)	θ value	5.27518 (rank : 2435)
Query Neighborhood Hits	2923	Target Neighborhood Hits	199	Shared Neighborhood Hits	46
SwissProt Accessions	P14434, O78195	Gene names	H2-Aa
Domain Architecture
Description	H-2 class II histocompatibility antigen, A-B alpha chain precursor (IAalpha).

NPAS2_HUMAN
NC score	-0.000892 (rank : 2875)	θ value	6.88961 (rank : 2661)
Query Neighborhood Hits	2923	Target Neighborhood Hits	150	Shared Neighborhood Hits	52
SwissProt Accessions	Q99743, Q99629	Gene names	NPAS2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2) (Member of PAS protein 4) (MOP4).

ANXA7_HUMAN
NC score	-0.000896 (rank : 2876)	θ value	1.81305 (rank : 1909)
Query Neighborhood Hits	2923	Target Neighborhood Hits	168	Shared Neighborhood Hits	50
SwissProt Accessions	P20073	Gene names	ANXA7, ANX7, SNX
Domain Architecture
Description	Annexin A7 (Annexin VII) (Synexin).

TNR3_HUMAN
NC score	-0.000962 (rank : 2877)	θ value	1.81305 (rank : 1996)
Query Neighborhood Hits	2923	Target Neighborhood Hits	145	Shared Neighborhood Hits	34
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

LV7A_HUMAN
NC score	-0.000981 (rank : 2878)	θ value	0.365318 (rank : 1558)
Query Neighborhood Hits	2923	Target Neighborhood Hits	193	Shared Neighborhood Hits	61
SwissProt Accessions	P01720	Gene names
Domain Architecture	No domain graphic available
Description	Ig lambda chain V-VII region MOT.

FREM2_MOUSE
NC score	-0.000988 (rank : 2879)	θ value	5.27518 (rank : 2424)
Query Neighborhood Hits	2923	Target Neighborhood Hits	73	Shared Neighborhood Hits	20
SwissProt Accessions	Q6NVD0, Q4W2Q5, Q5H8C0, Q811G9, Q8C4G5, Q8CD46	Gene names	Frem2, Nv1
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 2 precursor (ECM3 homolog) (NV domain-containing protein 1).

MTRR_HUMAN
NC score	-0.001025 (rank : 2880)	θ value	8.99809 (rank : 2835)
Query Neighborhood Hits	2923	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UBK8, O60471	Gene names	MTRR
Domain Architecture
Description	Methionine synthase reductase, mitochondrial precursor (EC 1.16.1.8) (MSR).

ZFYV9_HUMAN
NC score	-0.001074 (rank : 2881)	θ value	8.99809 (rank : 2919)
Query Neighborhood Hits	2923	Target Neighborhood Hits	134	Shared Neighborhood Hits	39
SwissProt Accessions	O95405, Q9UNE1, Q9Y5R7	Gene names	ZFYVE9, MADHIP, SARA, SMADIP
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Smad anchor for receptor activation) (Receptor activation anchor) (hSARA) (Novel serine protease) (NSP).

CHSTB_MOUSE
NC score	-0.001114 (rank : 2882)	θ value	8.99809 (rank : 2753)
Query Neighborhood Hits	2923	Target Neighborhood Hits	21	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JME2, Q9JJS2	Gene names	Chst11
Domain Architecture	No domain graphic available
Description	Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O- sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4ST) (C4ST-1) (C4S-1).

AIP_MOUSE
NC score	-0.001122 (rank : 2883)	θ value	8.99809 (rank : 2725)
Query Neighborhood Hits	2923	Target Neighborhood Hits	51	Shared Neighborhood Hits	8
SwissProt Accessions	O08915	Gene names	Aip
Domain Architecture
Description	AH receptor-interacting protein (AIP) (Aryl-hydrocarbon receptor- interacting protein).

HA2K_MOUSE
NC score	-0.001155 (rank : 2884)	θ value	5.27518 (rank : 2436)
Query Neighborhood Hits	2923	Target Neighborhood Hits	199	Shared Neighborhood Hits	46
SwissProt Accessions	P01910	Gene names	H2-Aa
Domain Architecture
Description	H-2 class II histocompatibility antigen, A-K alpha chain precursor.

SSX2_HUMAN
NC score	-0.001157 (rank : 2885)	θ value	4.03905 (rank : 2359)
Query Neighborhood Hits	2923	Target Neighborhood Hits	88	Shared Neighborhood Hits	14
SwissProt Accessions	Q16385, Q16404, Q5JS26, Q96IP7, Q9BU88	Gene names	SSX2
Domain Architecture
Description	Protein SSX2 (Synovial sarcoma, X breakpoint 2) (SSX) (HOM-MEL-40).

FAT2_HUMAN
NC score	-0.001160 (rank : 2886)	θ value	6.88961 (rank : 2599)
Query Neighborhood Hits	2923	Target Neighborhood Hits	507	Shared Neighborhood Hits	116
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

GBRL1_HUMAN
NC score	-0.001192 (rank : 2887)	θ value	8.99809 (rank : 2784)
Query Neighborhood Hits	2923	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H0R8	Gene names	GABARAPL1, GEC1
Domain Architecture
Description	Gamma-aminobutyric acid receptor-associated protein-like 1 (GABA(A) receptor-associated protein-like 1) (Glandular epithelial cell protein 1) (GEC-1) (Early estrogen-regulated protein).

GBRL1_MOUSE
NC score	-0.001192 (rank : 2888)	θ value	8.99809 (rank : 2785)
Query Neighborhood Hits	2923	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R3R8, Q3TG14, Q9JJ97	Gene names	Gabarapl1, Gec1
Domain Architecture
Description	Gamma-aminobutyric acid receptor-associated protein-like 1 (GABA(A) receptor-associated protein-like 1) (Glandular epithelial cell protein 1) (GEC-1).

BPIL3_MOUSE
NC score	-0.001214 (rank : 2889)	θ value	6.88961 (rank : 2552)
Query Neighborhood Hits	2923	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BU51, Q80ZU8	Gene names	Bpil3
Domain Architecture
Description	Bactericidal/permeability-increasing protein-like 3 precursor.

S39A6_MOUSE
NC score	-0.001249 (rank : 2890)	θ value	8.99809 (rank : 2871)
Query Neighborhood Hits	2923	Target Neighborhood Hits	48	Shared Neighborhood Hits	9
SwissProt Accessions	Q8C145, Q7TPP9, Q7TQE0, Q8R518	Gene names	Slc39a6
Domain Architecture	No domain graphic available
Description	Zinc transporter SLC39A6 precursor (Solute carrier family 39 member 6) (Endoplasmic reticulum membrane-linked protein) (Ermelin).

HA2S_MOUSE
NC score	-0.001266 (rank : 2891)	θ value	6.88961 (rank : 2617)
Query Neighborhood Hits	2923	Target Neighborhood Hits	200	Shared Neighborhood Hits	46
SwissProt Accessions	P14437	Gene names
Domain Architecture
Description	H-2 class II histocompatibility antigen, A-S alpha chain.

SNTB2_MOUSE
NC score	-0.001299 (rank : 2892)	θ value	0.813845 (rank : 1746)
Query Neighborhood Hits	2923	Target Neighborhood Hits	181	Shared Neighborhood Hits	38
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

KV1A_HUMAN
NC score	-0.001330 (rank : 2893)	θ value	3.0926 (rank : 2181)
Query Neighborhood Hits	2923	Target Neighborhood Hits	203	Shared Neighborhood Hits	69
SwissProt Accessions	P01593	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-I region AG.

GPDM_MOUSE
NC score	-0.001344 (rank : 2894)	θ value	6.88961 (rank : 2614)
Query Neighborhood Hits	2923	Target Neighborhood Hits	101	Shared Neighborhood Hits	8
SwissProt Accessions	Q64521, Q61507	Gene names	Gpd2, Gdm1
Domain Architecture
Description	Glycerol-3-phosphate dehydrogenase, mitochondrial precursor (EC 1.1.99.5) (GPD-M) (GPDH-M).

VAT1_MOUSE
NC score	-0.001482 (rank : 2895)	θ value	4.03905 (rank : 2366)
Query Neighborhood Hits	2923	Target Neighborhood Hits	41	Shared Neighborhood Hits	8
SwissProt Accessions	Q62465, Q8R3G0, Q8R3T8	Gene names	Vat1, Vat-1
Domain Architecture	No domain graphic available
Description	Synaptic vesicle membrane protein VAT-1 homolog (EC 1.-.-.-).

HA21_MOUSE
NC score	-0.001503 (rank : 2896)	θ value	2.36792 (rank : 2053)
Query Neighborhood Hits	2923	Target Neighborhood Hits	192	Shared Neighborhood Hits	42
SwissProt Accessions	P01904	Gene names	H2-Ea
Domain Architecture
Description	H-2 class II histocompatibility antigen, E-D alpha chain precursor (H2-IE-alpha).

TRPM6_MOUSE
NC score	-0.001540 (rank : 2897)	θ value	1.81305 (rank : 2000)
Query Neighborhood Hits	2923	Target Neighborhood Hits	78	Shared Neighborhood Hits	22
SwissProt Accessions	Q8CIR4	Gene names	Trpm6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6).

BIG1_HUMAN
NC score	-0.001578 (rank : 2898)	θ value	8.99809 (rank : 2737)
Query Neighborhood Hits	2923	Target Neighborhood Hits	76	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y6D6, Q9NV46, Q9UFV2, Q9UNL0	Gene names	ARFGEF1, ARFGEP1, BIG1
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Brefeldin A-inhibited GEP 1) (p200 ARF-GEP1) (p200 ARF guanine nucleotide exchange factor).

ENW1_HUMAN
NC score	-0.001616 (rank : 2899)	θ value	8.99809 (rank : 2776)
Query Neighborhood Hits	2923	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UQF0, O95244, O95245, Q8NHY7, Q9NRZ2, Q9NZG3	Gene names	ERVWE1
Domain Architecture
Description	HERV-W_7q21.2 provirus ancestral Env polyprotein precursor (Envelope polyprotein gPr73) (HERV-7q Envelope protein) (HERV-W envelope protein) (Syncytin) (Syncytin-1) (Enverin) (Env-W) [Contains: Surface protein (SU) (gp50); Transmembrane protein (TM) (gp24)].

CHSTB_HUMAN
NC score	-0.001638 (rank : 2900)	θ value	5.27518 (rank : 2399)
Query Neighborhood Hits	2923	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NPF2, Q9NXY6, Q9NY36	Gene names	CHST11
Domain Architecture	No domain graphic available
Description	Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O- sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4ST) (C4ST-1) (C4S-1).

NALP5_HUMAN
NC score	-0.001640 (rank : 2901)	θ value	1.06291 (rank : 1799)
Query Neighborhood Hits	2923	Target Neighborhood Hits	88	Shared Neighborhood Hits	12
SwissProt Accessions	P59047, Q86W29	Gene names	NALP5, MATER
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Mater protein homolog).

HA22_MOUSE
NC score	-0.001642 (rank : 2902)	θ value	2.36792 (rank : 2054)
Query Neighborhood Hits	2923	Target Neighborhood Hits	193	Shared Neighborhood Hits	43
SwissProt Accessions	P04224, Q31157	Gene names
Domain Architecture
Description	H-2 class II histocompatibility antigen, E-K alpha chain precursor.

WWP2_HUMAN
NC score	-0.001786 (rank : 2903)	θ value	6.88961 (rank : 2711)
Query Neighborhood Hits	2923	Target Neighborhood Hits	177	Shared Neighborhood Hits	63
SwissProt Accessions	O00308, Q96CZ2, Q9BWN6	Gene names	WWP2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2) (Atrophin-1-interacting protein 2) (AIP2).

KV1F_HUMAN
NC score	-0.001843 (rank : 2904)	θ value	5.27518 (rank : 2448)
Query Neighborhood Hits	2923	Target Neighborhood Hits	261	Shared Neighborhood Hits	78
SwissProt Accessions	P01598	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-I region EU.

FOLH1_MOUSE
NC score	-0.001853 (rank : 2905)	θ value	5.27518 (rank : 2422)
Query Neighborhood Hits	2923	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	O35409, Q9DCC2	Gene names	Folh1, Mopsm, Naalad1
Domain Architecture
Description	Glutamate carboxypeptidase 2 (EC 3.4.17.21) (Glutamate carboxypeptidase II) (Membrane glutamate carboxypeptidase) (mGCP) (N- acetylated-alpha-linked acidic dipeptidase I) (NAALADase I) (Pteroylpoly-gamma-glutamate carboxypeptidase) (Folylpoly-gamma- glutamate carboxypeptidase) (FGCP) (Folate hydrolase 1) (Prostate- specific membrane antigen homolog).

CAC1A_MOUSE
NC score	-0.001882 (rank : 2906)	θ value	6.88961 (rank : 2557)
Query Neighborhood Hits	2923	Target Neighborhood Hits	267	Shared Neighborhood Hits	82
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

DHX57_HUMAN
NC score	-0.001948 (rank : 2907)	θ value	8.99809 (rank : 2764)
Query Neighborhood Hits	2923	Target Neighborhood Hits	109	Shared Neighborhood Hits	27
SwissProt Accessions	Q6P158, Q53SI4, Q6P9G1, Q7Z6H3, Q8NG17, Q96M33	Gene names	DHX57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

PDE1C_HUMAN
NC score	-0.001984 (rank : 2908)	θ value	0.279714 (rank : 1515)
Query Neighborhood Hits	2923	Target Neighborhood Hits	134	Shared Neighborhood Hits	44
SwissProt Accessions	Q14123, Q14124	Gene names	PDE1C
Domain Architecture
Description	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (EC 3.1.4.17) (Cam-PDE 1C) (hCam-3).

ZFY16_MOUSE
NC score	-0.002055 (rank : 2909)	θ value	8.99809 (rank : 2918)
Query Neighborhood Hits	2923	Target Neighborhood Hits	108	Shared Neighborhood Hits	25
SwissProt Accessions	Q80U44, Q8BRD2, Q8CG97	Gene names	Zfyve16, Kiaa0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosomal- associated FYVE domain protein).

KV1H_HUMAN
NC score	-0.002113 (rank : 2910)	θ value	8.99809 (rank : 2815)
Query Neighborhood Hits	2923	Target Neighborhood Hits	283	Shared Neighborhood Hits	85
SwissProt Accessions	P01600	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-I region Hau.

MIS_MOUSE
NC score	-0.002214 (rank : 2911)	θ value	4.03905 (rank : 2316)
Query Neighborhood Hits	2923	Target Neighborhood Hits	86	Shared Neighborhood Hits	10
SwissProt Accessions	P27106	Gene names	Amh
Domain Architecture
Description	Muellerian-inhibiting factor precursor (MIS) (Anti-Muellerian hormone) (AMH) (Muellerian-inhibiting substance).

PAP2_HUMAN
NC score	-0.002290 (rank : 2912)	θ value	5.27518 (rank : 2471)
Query Neighborhood Hits	2923	Target Neighborhood Hits	106	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BXP8, Q96PH7, Q96PH8, Q9H4C9	Gene names	PAPPA2
Domain Architecture	No domain graphic available
Description	Pappalysin-2 precursor (EC 3.4.24.-) (Pregnancy-associated plasma protein-A2) (PAPP-A2) (Pregnancy-associated plasma protein-E1) (PAPP- E).

TSH3_MOUSE
NC score	-0.002331 (rank : 2913)	θ value	3.0926 (rank : 2230)
Query Neighborhood Hits	2923	Target Neighborhood Hits	590	Shared Neighborhood Hits	95
SwissProt Accessions	Q8CGV9, Q5DTX4	Gene names	Tshz3, Kiaa1474, Tsh3, Zfp537, Znf537
Domain Architecture	No domain graphic available
Description	Teashirt homolog 3 (Zinc finger protein 537).

HB2S_MOUSE
NC score	-0.002334 (rank : 2914)	θ value	8.99809 (rank : 2791)
Query Neighborhood Hits	2923	Target Neighborhood Hits	202	Shared Neighborhood Hits	50
SwissProt Accessions	P06345	Gene names	H2-Ab1
Domain Architecture
Description	H-2 class II histocompatibility antigen, A-S beta chain precursor.

SMP1L_MOUSE
NC score	-0.002351 (rank : 2915)	θ value	6.88961 (rank : 2693)
Query Neighborhood Hits	2923	Target Neighborhood Hits	70	Shared Neighborhood Hits	14
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

DCBD2_HUMAN
NC score	-0.002358 (rank : 2916)	θ value	5.27518 (rank : 2405)
Query Neighborhood Hits	2923	Target Neighborhood Hits	118	Shared Neighborhood Hits	13
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

RBM28_MOUSE
NC score	-0.002385 (rank : 2917)	θ value	3.0926 (rank : 2215)
Query Neighborhood Hits	2923	Target Neighborhood Hits	368	Shared Neighborhood Hits	92
SwissProt Accessions	Q8CGC6, Q8BG25, Q8VEJ8, Q9CS22, Q9CSE6	Gene names	Rbm28
Domain Architecture	No domain graphic available
Description	RNA-binding protein 28 (RNA-binding motif protein 28).

TSH2_HUMAN
NC score	-0.002488 (rank : 2918)	θ value	8.99809 (rank : 2904)
Query Neighborhood Hits	2923	Target Neighborhood Hits	479	Shared Neighborhood Hits	85
SwissProt Accessions	Q9NRE2, Q4VXM4, Q6N003, Q8N260	Gene names	TSHZ2, C20orf17, TSH2, ZNF218
Domain Architecture	No domain graphic available
Description	Teashirt homolog 2 (Zinc finger protein 218) (Ovarian cancer-related protein 10-2) (OVC10-2).

GRSF1_MOUSE
NC score	-0.002504 (rank : 2919)	θ value	6.88961 (rank : 2616)
Query Neighborhood Hits	2923	Target Neighborhood Hits	60	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C5Q4, Q8BR05, Q8BRG7	Gene names	Grsf1
Domain Architecture	No domain graphic available
Description	G-rich sequence factor 1 (GRSF-1).

ZHX1_MOUSE
NC score	-0.002542 (rank : 2920)	θ value	6.88961 (rank : 2715)
Query Neighborhood Hits	2923	Target Neighborhood Hits	334	Shared Neighborhood Hits	47
SwissProt Accessions	P70121, Q8BQ68, Q8C6T4, Q8CJG3	Gene names	Zhx1
Domain Architecture
Description	Zinc fingers and homeoboxes protein 1.

RBM34_HUMAN
NC score	-0.002555 (rank : 2921)	θ value	0.21417 (rank : 1475)
Query Neighborhood Hits	2923	Target Neighborhood Hits	208	Shared Neighborhood Hits	36
SwissProt Accessions	P42696, Q8N2Z8, Q9H5A1	Gene names	RBM34, KIAA0117
Domain Architecture
Description	RNA-binding protein 34 (RNA-binding motif protein 34).

S12A5_MOUSE
NC score	-0.002590 (rank : 2922)	θ value	4.03905 (rank : 2349)
Query Neighborhood Hits	2923	Target Neighborhood Hits	59	Shared Neighborhood Hits	12
SwissProt Accessions	Q91V14, Q9Z0M7	Gene names	Slc12a5, Kcc2
Domain Architecture
Description	Solute carrier family 12 member 5 (Electroneutral potassium-chloride cotransporter 2) (K-Cl cotransporter 2) (Neuronal K-Cl cotransporter) (mKCC2).

KV5K_MOUSE
NC score	-0.002597 (rank : 2923)	θ value	8.99809 (rank : 2818)
Query Neighborhood Hits	2923	Target Neighborhood Hits	214	Shared Neighborhood Hits	75
SwissProt Accessions	P01644	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-V region HP R16.7.

S27A1_HUMAN
NC score	-0.002598 (rank : 2924)	θ value	4.03905 (rank : 2350)
Query Neighborhood Hits	2923	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q6PCB7	Gene names	SLC27A1, ACSVL5, FATP1
Domain Architecture	No domain graphic available
Description	Long-chain fatty acid transport protein 1 (EC 6.2.1.-) (Fatty acid transport protein 1) (FATP-1) (Solute carrier family 27 member 1).

KV5N_MOUSE
NC score	-0.002626 (rank : 2925)	θ value	3.0926 (rank : 2183)
Query Neighborhood Hits	2923	Target Neighborhood Hits	206	Shared Neighborhood Hits	70
SwissProt Accessions	P01647	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-V region HP 124E1.

S26A2_HUMAN
NC score	-0.002644 (rank : 2926)	θ value	8.99809 (rank : 2870)
Query Neighborhood Hits	2923	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	P50443	Gene names	SLC26A2, DTD, DTDST
Domain Architecture
Description	Sulfate transporter (Diastrophic dysplasia protein) (Solute carrier family 26 member 2).

ETV1_HUMAN
NC score	-0.002664 (rank : 2927)	θ value	8.99809 (rank : 2780)
Query Neighborhood Hits	2923	Target Neighborhood Hits	107	Shared Neighborhood Hits	33
SwissProt Accessions	P50549, O75849, Q9UQ71, Q9Y636	Gene names	ETV1, ER81
Domain Architecture
Description	ETS translocation variant 1 (ER81 protein).

RGS9_MOUSE
NC score	-0.002763 (rank : 2928)	θ value	6.88961 (rank : 2683)
Query Neighborhood Hits	2923	Target Neighborhood Hits	65	Shared Neighborhood Hits	8
SwissProt Accessions	O54828, Q9Z0S0	Gene names	Rgs9
Domain Architecture
Description	Regulator of G-protein signaling 9 (RGS9).

KV6H_MOUSE
NC score	-0.002779 (rank : 2929)	θ value	5.27518 (rank : 2452)
Query Neighborhood Hits	2923	Target Neighborhood Hits	279	Shared Neighborhood Hits	79
SwissProt Accessions	P04942	Gene names
Domain Architecture
Description	Ig kappa chain V-VI region NQ5-61.1.2.

GABPA_HUMAN
NC score	-0.002800 (rank : 2930)	θ value	3.0926 (rank : 2173)
Query Neighborhood Hits	2923	Target Neighborhood Hits	55	Shared Neighborhood Hits	9
SwissProt Accessions	Q06546, Q12939	Gene names	GABPA, E4TF1A
Domain Architecture
Description	GA-binding protein alpha chain (GABP-subunit alpha) (Transcription factor E4TF1-60) (Nuclear respiratory factor 2 subunit alpha).

WWP2_MOUSE
NC score	-0.002803 (rank : 2931)	θ value	6.88961 (rank : 2712)
Query Neighborhood Hits	2923	Target Neighborhood Hits	118	Shared Neighborhood Hits	34
SwissProt Accessions	Q9DBH0, Q8BTG4, Q923F6	Gene names	Wwp2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2).

KV6I_MOUSE
NC score	-0.002918 (rank : 2932)	θ value	6.88961 (rank : 2641)
Query Neighborhood Hits	2923	Target Neighborhood Hits	272	Shared Neighborhood Hits	77
SwissProt Accessions	P04943	Gene names
Domain Architecture
Description	Ig kappa chain V-VI region NQ6-8.3.1.

TROP_HUMAN
NC score	-0.002939 (rank : 2933)	θ value	1.81305 (rank : 1999)
Query Neighborhood Hits	2923	Target Neighborhood Hits	158	Shared Neighborhood Hits	26
SwissProt Accessions	Q12816, Q9NU89, Q9UPN8	Gene names	TRO, KIAA1114, MAGED3
Domain Architecture
Description	Trophinin (MAGE-D3 antigen).

TNR1B_MOUSE
NC score	-0.002965 (rank : 2934)	θ value	8.99809 (rank : 2901)
Query Neighborhood Hits	2923	Target Neighborhood Hits	123	Shared Neighborhood Hits	21
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

CLCN2_MOUSE
NC score	-0.003061 (rank : 2935)	θ value	5.27518 (rank : 2400)
Query Neighborhood Hits	2923	Target Neighborhood Hits	34	Shared Neighborhood Hits	7
SwissProt Accessions	Q9R0A1, Q9WUJ9	Gene names	Clcn2, Clc2
Domain Architecture
Description	Chloride channel protein 2 (ClC-2).

DICER_HUMAN
NC score	-0.003088 (rank : 2936)	θ value	5.27518 (rank : 2408)
Query Neighborhood Hits	2923	Target Neighborhood Hits	126	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UPY3, O95943, Q9UQ02	Gene names	DICER1, DICER, HERNA, KIAA0928
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Helicase with RNase motif) (Helicase-MOI).

KV1L_HUMAN
NC score	-0.003106 (rank : 2937)	θ value	1.38821 (rank : 1860)
Query Neighborhood Hits	2923	Target Neighborhood Hits	239	Shared Neighborhood Hits	68
SwissProt Accessions	P01604	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-I region Kue.

KV1R_HUMAN
NC score	-0.003164 (rank : 2938)	θ value	8.99809 (rank : 2816)
Query Neighborhood Hits	2923	Target Neighborhood Hits	253	Shared Neighborhood Hits	75
SwissProt Accessions	P01610	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-I region WEA.

UBP29_HUMAN
NC score	-0.003243 (rank : 2939)	θ value	3.0926 (rank : 2233)
Query Neighborhood Hits	2923	Target Neighborhood Hits	94	Shared Neighborhood Hits	12
SwissProt Accessions	Q9HBJ7	Gene names	USP29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

K0317_MOUSE
NC score	-0.003247 (rank : 2940)	θ value	8.99809 (rank : 2806)
Query Neighborhood Hits	2923	Target Neighborhood Hits	43	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CHG5, Q6P9Q1, Q80YC4, Q8C5W5	Gene names	Kiaa0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

PCOC1_HUMAN
NC score	-0.003303 (rank : 2941)	θ value	1.81305 (rank : 1966)
Query Neighborhood Hits	2923	Target Neighborhood Hits	146	Shared Neighborhood Hits	35
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

KV3M_MOUSE
NC score	-0.003345 (rank : 2942)	θ value	6.88961 (rank : 2634)
Query Neighborhood Hits	2923	Target Neighborhood Hits	238	Shared Neighborhood Hits	74
SwissProt Accessions	P01665	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-III region PC 7043.

KV1B_HUMAN
NC score	-0.003361 (rank : 2943)	θ value	2.36792 (rank : 2070)
Query Neighborhood Hits	2923	Target Neighborhood Hits	244	Shared Neighborhood Hits	68
SwissProt Accessions	P01594	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-I region AU.

KV1T_HUMAN
NC score	-0.003366 (rank : 2944)	θ value	8.99809 (rank : 2817)
Query Neighborhood Hits	2923	Target Neighborhood Hits	256	Shared Neighborhood Hits	75
SwissProt Accessions	P01612	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-I region Mev.

KV3N_MOUSE
NC score	-0.003448 (rank : 2945)	θ value	6.88961 (rank : 2635)
Query Neighborhood Hits	2923	Target Neighborhood Hits	236	Shared Neighborhood Hits	75
SwissProt Accessions	P01666	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-III region PC 7183.

KV6F_MOUSE
NC score	-0.003455 (rank : 2946)	θ value	6.88961 (rank : 2639)
Query Neighborhood Hits	2923	Target Neighborhood Hits	277	Shared Neighborhood Hits	77
SwissProt Accessions	P04940	Gene names
Domain Architecture
Description	Ig kappa chain V-VI region NQ2-17.4.1.

SATT_MOUSE
NC score	-0.003474 (rank : 2947)	θ value	8.99809 (rank : 2873)
Query Neighborhood Hits	2923	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	O35874	Gene names	Slc1a4, Asct1
Domain Architecture
Description	Neutral amino acid transporter A (SATT) (Alanine/serine/cysteine/ threonine transporter) (ASCT1).

KV3O_MOUSE
NC score	-0.003502 (rank : 2948)	θ value	6.88961 (rank : 2636)
Query Neighborhood Hits	2923	Target Neighborhood Hits	242	Shared Neighborhood Hits	76
SwissProt Accessions	P01667	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-III region PC 6308.

IRTF_HUMAN
NC score	-0.003510 (rank : 2949)	θ value	8.99809 (rank : 2801)
Query Neighborhood Hits	2923	Target Neighborhood Hits	41	Shared Neighborhood Hits	11
SwissProt Accessions	Q00978	Gene names	ISGF3G, IRF9
Domain Architecture
Description	Transcriptional regulator ISGF3 subunit gamma (Interferon regulatory factor 9) (IRF-9) (IFN-alpha-responsive transcription factor subunit) (Interferon-stimulated gene factor 3 gamma) (ISGF3 p48 subunit) (ISGF- 3 gamma).

KV6G_MOUSE
NC score	-0.003550 (rank : 2950)	θ value	6.88961 (rank : 2640)
Query Neighborhood Hits	2923	Target Neighborhood Hits	278	Shared Neighborhood Hits	77
SwissProt Accessions	P04941	Gene names
Domain Architecture
Description	Ig kappa chain V-VI region NQ2-48.2.2.

K1196_HUMAN
NC score	-0.003563 (rank : 2951)	θ value	2.36792 (rank : 2066)
Query Neighborhood Hits	2923	Target Neighborhood Hits	618	Shared Neighborhood Hits	78
SwissProt Accessions	Q96KM6, Q9ULM4	Gene names	KIAA1196
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1196.

CACP_MOUSE
NC score	-0.003578 (rank : 2952)	θ value	8.99809 (rank : 2742)
Query Neighborhood Hits	2923	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	P47934, Q923A6	Gene names	Crat
Domain Architecture
Description	Carnitine O-acetyltransferase (EC 2.3.1.7) (Carnitine acetylase) (CAT) (Carnitine acetyltransferase) (CrAT).

EPB42_MOUSE
NC score	-0.003674 (rank : 2953)	θ value	8.99809 (rank : 2777)
Query Neighborhood Hits	2923	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	P49222	Gene names	Epb42, Epb4.2
Domain Architecture
Description	Erythrocyte membrane protein band 4.2 (Erythrocyte protein 4.2) (P4.2).

ZHX1_HUMAN
NC score	-0.003808 (rank : 2954)	θ value	6.88961 (rank : 2714)
Query Neighborhood Hits	2923	Target Neighborhood Hits	307	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UKY1, Q8IWD8	Gene names	ZHX1
Domain Architecture
Description	Zinc fingers and homeoboxes protein 1.

KV3Q_MOUSE
NC score	-0.003813 (rank : 2955)	θ value	6.88961 (rank : 2637)
Query Neighborhood Hits	2923	Target Neighborhood Hits	225	Shared Neighborhood Hits	70
SwissProt Accessions	P01669	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-III region PC 7769.

RBM28_HUMAN
NC score	-0.003850 (rank : 2956)	θ value	1.06291 (rank : 1807)
Query Neighborhood Hits	2923	Target Neighborhood Hits	307	Shared Neighborhood Hits	55
SwissProt Accessions	Q9NW13, Q96CV3	Gene names	RBM28
Domain Architecture	No domain graphic available
Description	RNA-binding protein 28 (RNA-binding motif protein 28).

KV1K_HUMAN
NC score	-0.003964 (rank : 2957)	θ value	6.88961 (rank : 2633)
Query Neighborhood Hits	2923	Target Neighborhood Hits	220	Shared Neighborhood Hits	65
SwissProt Accessions	P01603	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-I region Ka.

KTNA1_MOUSE
NC score	-0.004121 (rank : 2958)	θ value	0.365318 (rank : 1555)
Query Neighborhood Hits	2923	Target Neighborhood Hits	123	Shared Neighborhood Hits	25
SwissProt Accessions	Q9WV86	Gene names	Katna1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A1 (EC 3.6.4.3) (Katanin p60 subunit A1) (p60 katanin) (Lipotransin).

KV3H_MOUSE
NC score	-0.004278 (rank : 2959)	θ value	2.36792 (rank : 2071)
Query Neighborhood Hits	2923	Target Neighborhood Hits	243	Shared Neighborhood Hits	70
SwissProt Accessions	P01660	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-III region PC 3741/TEPC 111.

IRX3_MOUSE
NC score	-0.004316 (rank : 2960)	θ value	8.99809 (rank : 2802)
Query Neighborhood Hits	2923	Target Neighborhood Hits	303	Shared Neighborhood Hits	51
SwissProt Accessions	P81067	Gene names	Irx3, Irxb1
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-3 (Iroquois homeobox protein 3) (Homeodomain protein IRXB1).

WDR79_HUMAN
NC score	-0.004319 (rank : 2961)	θ value	8.99809 (rank : 2915)
Query Neighborhood Hits	2923	Target Neighborhood Hits	246	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BUR4, Q9NW09	Gene names	WDR79
Domain Architecture	No domain graphic available
Description	WD repeat protein 79.

TBX10_MOUSE
NC score	-0.004332 (rank : 2962)	θ value	5.27518 (rank : 2523)
Query Neighborhood Hits	2923	Target Neighborhood Hits	47	Shared Neighborhood Hits	7
SwissProt Accessions	Q810F8, O54841, Q6QH75	Gene names	Tbx10, Tbx13, Tbx7
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX10 (T-box protein 10) (T-box protein 13) (MmTBX7).

KV3J_MOUSE
NC score	-0.004381 (rank : 2963)	θ value	4.03905 (rank : 2302)
Query Neighborhood Hits	2923	Target Neighborhood Hits	242	Shared Neighborhood Hits	71
SwissProt Accessions	P01662	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-III region ABPC 22/PC 9245.

KV3I_MOUSE
NC score	-0.004401 (rank : 2964)	θ value	4.03905 (rank : 2301)
Query Neighborhood Hits	2923	Target Neighborhood Hits	242	Shared Neighborhood Hits	70
SwissProt Accessions	P01661	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-III region MOPC 63 precursor.

KV3K_MOUSE
NC score	-0.004600 (rank : 2965)	θ value	4.03905 (rank : 2303)
Query Neighborhood Hits	2923	Target Neighborhood Hits	241	Shared Neighborhood Hits	69
SwissProt Accessions	P01663	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-III region PC 4050.

LV6A_HUMAN
NC score	-0.004616 (rank : 2966)	θ value	4.03905 (rank : 2312)
Query Neighborhood Hits	2923	Target Neighborhood Hits	284	Shared Neighborhood Hits	75
SwissProt Accessions	P01721	Gene names
Domain Architecture	No domain graphic available
Description	Ig lambda chain V-VI region AR.

KV5S_MOUSE
NC score	-0.004623 (rank : 2967)	θ value	2.36792 (rank : 2074)
Query Neighborhood Hits	2923	Target Neighborhood Hits	243	Shared Neighborhood Hits	67
SwissProt Accessions	P01652	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-V region J606.

KV5Q_MOUSE
NC score	-0.004670 (rank : 2968)	θ value	5.27518 (rank : 2451)
Query Neighborhood Hits	2923	Target Neighborhood Hits	242	Shared Neighborhood Hits	68
SwissProt Accessions	P01650	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-V region UPC 61.

FOXC2_HUMAN
NC score	-0.004687 (rank : 2969)	θ value	0.62314 (rank : 1665)
Query Neighborhood Hits	2923	Target Neighborhood Hits	236	Shared Neighborhood Hits	63
SwissProt Accessions	Q99958	Gene names	FOXC2, FKHL14, MFH1
Domain Architecture
Description	Forkhead box protein C2 (Forkhead-related protein FKHL14) (Mesenchyme fork head protein 1) (MFH-1 protein) (Transcription factor FKH-14).

PECR_HUMAN
NC score	-0.004775 (rank : 2970)	θ value	1.81305 (rank : 1967)
Query Neighborhood Hits	2923	Target Neighborhood Hits	77	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BY49, Q6IAK9, Q9NRD4, Q9NY60, Q9P1A4	Gene names	PECR
Domain Architecture	No domain graphic available
Description	Peroxisomal trans-2-enoyl-CoA reductase (EC 1.3.1.38) (TERP) (HPDHase) (pVI-ARL) (2,4-dienoyl-CoA reductase-related protein) (DCR-RP).

KCNQ2_MOUSE
NC score	-0.004800 (rank : 2971)	θ value	8.99809 (rank : 2808)
Query Neighborhood Hits	2923	Target Neighborhood Hits	163	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Z351, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350	Gene names	Kcnq2, Kqt2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Potassium channel subunit alpha KvLQT2) (KQT-like 2).

RBBP5_HUMAN
NC score	-0.004809 (rank : 2972)	θ value	4.03905 (rank : 2340)
Query Neighborhood Hits	2923	Target Neighborhood Hits	372	Shared Neighborhood Hits	79
SwissProt Accessions	Q15291	Gene names	RBBP5, RBQ3
Domain Architecture
Description	Retinoblastoma-binding protein 5 (RBBP-5) (Retinoblastoma-binding protein RBQ-3).

KV5T_MOUSE
NC score	-0.004864 (rank : 2973)	θ value	6.88961 (rank : 2638)
Query Neighborhood Hits	2923	Target Neighborhood Hits	243	Shared Neighborhood Hits	67
SwissProt Accessions	P01653	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-V region W3082.

TVC4_MOUSE
NC score	-0.004923 (rank : 2974)	θ value	6.88961 (rank : 2707)
Query Neighborhood Hits	2923	Target Neighborhood Hits	246	Shared Neighborhood Hits	62
SwissProt Accessions	P06325	Gene names
Domain Architecture	No domain graphic available
Description	T-cell receptor gamma chain V region 5/10-13 precursor.

KCNQ3_HUMAN
NC score	-0.004969 (rank : 2975)	θ value	2.36792 (rank : 2067)
Query Neighborhood Hits	2923	Target Neighborhood Hits	114	Shared Neighborhood Hits	16
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

PRGR_MOUSE
NC score	-0.004987 (rank : 2976)	θ value	0.62314 (rank : 1685)
Query Neighborhood Hits	2923	Target Neighborhood Hits	286	Shared Neighborhood Hits	65
SwissProt Accessions	Q00175	Gene names	Pgr, Nr3c3, Pr
Domain Architecture
Description	Progesterone receptor (PR).

DHRS1_HUMAN
NC score	-0.005008 (rank : 2977)	θ value	6.88961 (rank : 2582)
Query Neighborhood Hits	2923	Target Neighborhood Hits	61	Shared Neighborhood Hits	4
SwissProt Accessions	Q96LJ7, Q8NDG3, Q96B59, Q96CQ5	Gene names	DHRS1
Domain Architecture
Description	Dehydrogenase/reductase SDR family member 1 (EC 1.1.-.-).

ABCA2_HUMAN
NC score	-0.005113 (rank : 2978)	θ value	0.813845 (rank : 1701)
Query Neighborhood Hits	2923	Target Neighborhood Hits	143	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BZC7	Gene names	ABCA2, ABC2
Domain Architecture
Description	ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2).

KV5A_MOUSE
NC score	-0.005188 (rank : 2979)	θ value	5.27518 (rank : 2449)
Query Neighborhood Hits	2923	Target Neighborhood Hits	233	Shared Neighborhood Hits	63
SwissProt Accessions	P01633	Gene names
Domain Architecture
Description	Ig kappa chain V-V region MPC11 precursor.

PECR_MOUSE
NC score	-0.005303 (rank : 2980)	θ value	5.27518 (rank : 2491)
Query Neighborhood Hits	2923	Target Neighborhood Hits	73	Shared Neighborhood Hits	5
SwissProt Accessions	Q99MZ7, Q9CX01, Q9JIF4	Gene names	Pecr
Domain Architecture	No domain graphic available
Description	Peroxisomal trans-2-enoyl-CoA reductase (EC 1.3.1.38).

UBP14_HUMAN
NC score	-0.005382 (rank : 2981)	θ value	8.99809 (rank : 2910)
Query Neighborhood Hits	2923	Target Neighborhood Hits	89	Shared Neighborhood Hits	13
SwissProt Accessions	P54578	Gene names	USP14, TGT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

DDX10_HUMAN
NC score	-0.005450 (rank : 2982)	θ value	3.0926 (rank : 2152)
Query Neighborhood Hits	2923	Target Neighborhood Hits	210	Shared Neighborhood Hits	73
SwissProt Accessions	Q13206, Q5BJD8	Gene names	DDX10
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

LV1B_HUMAN
NC score	-0.005482 (rank : 2983)	θ value	8.99809 (rank : 2828)
Query Neighborhood Hits	2923	Target Neighborhood Hits	237	Shared Neighborhood Hits	61
SwissProt Accessions	P01700	Gene names
Domain Architecture	No domain graphic available
Description	Ig lambda chain V-I region HA.

LV2F_HUMAN
NC score	-0.005490 (rank : 2984)	θ value	5.27518 (rank : 2456)
Query Neighborhood Hits	2923	Target Neighborhood Hits	253	Shared Neighborhood Hits	63
SwissProt Accessions	P01709	Gene names
Domain Architecture	No domain graphic available
Description	Ig lambda chain V-II region MGC.

BNC1_HUMAN
NC score	-0.005535 (rank : 2985)	θ value	3.0926 (rank : 2133)
Query Neighborhood Hits	2923	Target Neighborhood Hits	460	Shared Neighborhood Hits	50
SwissProt Accessions	Q01954, Q15840	Gene names	BNC1, BNC
Domain Architecture	No domain graphic available
Description	Zinc finger protein basonuclin-1.

PDE6C_MOUSE
NC score	-0.005571 (rank : 2986)	θ value	5.27518 (rank : 2488)
Query Neighborhood Hits	2923	Target Neighborhood Hits	45	Shared Neighborhood Hits	6
SwissProt Accessions	Q91ZQ1, Q8R0D4	Gene names	Pde6c
Domain Architecture	No domain graphic available
Description	Cone cGMP-specific 3',5'-cyclic phosphodiesterase alpha'-subunit (EC 3.1.4.35) (cGMP phosphodiesterase 6C).

ORCT3_MOUSE
NC score	-0.005617 (rank : 2987)	θ value	8.99809 (rank : 2847)
Query Neighborhood Hits	2923	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	Q6A4L0, Q8VC89	Gene names	Slc22a13
Domain Architecture	No domain graphic available
Description	Organic cation transporter-like 3 (Solute carrier family 22 member 13).

AT2A3_MOUSE
NC score	-0.005621 (rank : 2988)	θ value	2.36792 (rank : 2017)
Query Neighborhood Hits	2923	Target Neighborhood Hits	73	Shared Neighborhood Hits	10
SwissProt Accessions	Q64518, O70625, Q64517	Gene names	Atp2a3
Domain Architecture
Description	Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 (EC 3.6.3.8) (Calcium pump 3) (SERCA3) (SR Ca(2+)-ATPase 3).

UBPW_MOUSE
NC score	-0.005700 (rank : 2989)	θ value	2.36792 (rank : 2118)
Query Neighborhood Hits	2923	Target Neighborhood Hits	89	Shared Neighborhood Hits	10
SwissProt Accessions	Q61068	Gene names	Dub1, Dub-1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase DUB-1 (EC 3.1.2.15) (Ubiquitin thioesterase DUB-1) (Ubiquitin-specific-processing protease DUB-1) (Deubiquitinating enzyme 1).

RBP2_HUMAN
NC score	-0.005751 (rank : 2990)	θ value	8.99809 (rank : 2865)
Query Neighborhood Hits	2923	Target Neighborhood Hits	249	Shared Neighborhood Hits	59
SwissProt Accessions	P49792, Q13074, Q15280, Q53TE2, Q59FH7	Gene names	RANBP2, NUP358
Domain Architecture
Description	Ran-binding protein 2 (RanBP2) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (358 kDa nucleoporin) (P270).

AT2A3_HUMAN
NC score	-0.005785 (rank : 2991)	θ value	2.36792 (rank : 2016)
Query Neighborhood Hits	2923	Target Neighborhood Hits	71	Shared Neighborhood Hits	5
SwissProt Accessions	Q93084, O60900, O60901, O75501, O75502, Q16115, Q8TEX5, Q8TEX6	Gene names	ATP2A3
Domain Architecture
Description	Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 (EC 3.6.3.8) (Calcium pump 3) (SERCA3) (SR Ca(2+)-ATPase 3).

UBP47_HUMAN
NC score	-0.005827 (rank : 2992)	θ value	8.99809 (rank : 2912)
Query Neighborhood Hits	2923	Target Neighborhood Hits	149	Shared Neighborhood Hits	28
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

EMAL4_HUMAN
NC score	-0.005919 (rank : 2993)	θ value	5.27518 (rank : 2417)
Query Neighborhood Hits	2923	Target Neighborhood Hits	306	Shared Neighborhood Hits	51
SwissProt Accessions	Q9HC35	Gene names	EML4, C2orf2, EMAPL4
Domain Architecture
Description	Echinoderm microtubule-associated protein-like 4 (EMAP-4) (Restrictedly overexpressed proliferation-associated protein) (Ropp 120).

ABCA2_MOUSE
NC score	-0.005980 (rank : 2994)	θ value	8.99809 (rank : 2720)
Query Neighborhood Hits	2923	Target Neighborhood Hits	124	Shared Neighborhood Hits	22
SwissProt Accessions	P41234	Gene names	Abca2, Abc2
Domain Architecture
Description	ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2).

NMDE1_MOUSE
NC score	-0.006024 (rank : 2995)	θ value	6.88961 (rank : 2659)
Query Neighborhood Hits	2923	Target Neighborhood Hits	84	Shared Neighborhood Hits	17
SwissProt Accessions	P35436	Gene names	Grin2a
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit epsilon 1 precursor (N-methyl D- aspartate receptor subtype 2A) (NR2A) (NMDAR2A).

LV1H_HUMAN
NC score	-0.006060 (rank : 2996)	θ value	5.27518 (rank : 2455)
Query Neighborhood Hits	2923	Target Neighborhood Hits	255	Shared Neighborhood Hits	60
SwissProt Accessions	P06887	Gene names
Domain Architecture	No domain graphic available
Description	Ig lambda chain V-I region MEM.

ATBF1_MOUSE
NC score	-0.006138 (rank : 2997)	θ value	1.81305 (rank : 1913)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1841	Shared Neighborhood Hits	403
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

MMP17_MOUSE
NC score	-0.006265 (rank : 2998)	θ value	3.0926 (rank : 2190)
Query Neighborhood Hits	2923	Target Neighborhood Hits	60	Shared Neighborhood Hits	6
SwissProt Accessions	Q9R0S3	Gene names	Mmp17, Mt4mmp
Domain Architecture
Description	Matrix metalloproteinase-17 precursor (EC 3.4.24.-) (MMP-17) (Membrane-type matrix metalloproteinase 4) (MT-MMP 4) (Membrane-type-4 matrix metalloproteinase) (MT4-MMP).

FREA_HUMAN
NC score	-0.006363 (rank : 2999)	θ value	5.27518 (rank : 2423)
Query Neighborhood Hits	2923	Target Neighborhood Hits	205	Shared Neighborhood Hits	48
SwissProt Accessions	O43638, Q96D28	Gene names	FKHL18, FREAC10
Domain Architecture	No domain graphic available
Description	Forkhead-related transcription factor 10 (FREAC-10) (Forkhead-like 18 protein).

SOX8_HUMAN
NC score	-0.006463 (rank : 3000)	θ value	6.88961 (rank : 2694)
Query Neighborhood Hits	2923	Target Neighborhood Hits	100	Shared Neighborhood Hits	19
SwissProt Accessions	P57073, Q9NZW2	Gene names	SOX8
Domain Architecture
Description	Transcription factor SOX-8.

LV2G_HUMAN
NC score	-0.006498 (rank : 3001)	θ value	6.88961 (rank : 2646)
Query Neighborhood Hits	2923	Target Neighborhood Hits	263	Shared Neighborhood Hits	62
SwissProt Accessions	P01710	Gene names
Domain Architecture	No domain graphic available
Description	Ig lambda chain V-II region BO.

GNA14_HUMAN
NC score	-0.006503 (rank : 3002)	θ value	5.27518 (rank : 2430)
Query Neighborhood Hits	2923	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	O95837	Gene names	GNA14
Domain Architecture
Description	Guanine nucleotide-binding protein alpha-14 subunit (G-protein alpha subunit 14).

DHRS9_HUMAN
NC score	-0.006592 (rank : 3003)	θ value	6.88961 (rank : 2583)
Query Neighborhood Hits	2923	Target Neighborhood Hits	65	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BPW9, Q5RKX1, Q9NRA9, Q9NRB0	Gene names	DHRS9
Domain Architecture	No domain graphic available
Description	Dehydrogenase/reductase SDR family member 9 precursor (EC 1.1.-.-) (3- alpha hydroxysteroid dehydrogenase) (3alpha-HSD) (RDH-E2) (Short-chain dehydrogenase/reductase retSDR8) (NADP-dependent retinol dehydrogenase/reductase) (RDHL).

ITA8_HUMAN
NC score	-0.006598 (rank : 3004)	θ value	8.99809 (rank : 2803)
Query Neighborhood Hits	2923	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	P53708, Q5VX94	Gene names	ITGA8
Domain Architecture
Description	Integrin alpha-8 precursor [Contains: Integrin alpha-8 heavy chain; Integrin alpha-8 light chain].

LV2B_HUMAN
NC score	-0.006710 (rank : 3005)	θ value	6.88961 (rank : 2645)
Query Neighborhood Hits	2923	Target Neighborhood Hits	234	Shared Neighborhood Hits	62
SwissProt Accessions	P01705	Gene names
Domain Architecture	No domain graphic available
Description	Ig lambda chain V-II region NEI.

PCD16_HUMAN
NC score	-0.006744 (rank : 3006)	θ value	5.27518 (rank : 2472)
Query Neighborhood Hits	2923	Target Neighborhood Hits	245	Shared Neighborhood Hits	75
SwissProt Accessions	Q96JQ0, O15098	Gene names	DCHS1, CDH19, FIB1, KIAA1773, PCDH16
Domain Architecture
Description	Protocadherin-16 precursor (Dachsous 1) (Cadherin-19) (Fibroblast cadherin 1).

ABC8A_MOUSE
NC score	-0.006988 (rank : 3007)	θ value	3.0926 (rank : 2124)
Query Neighborhood Hits	2923	Target Neighborhood Hits	115	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K442, Q6PAV3, Q8C0A9, Q8R0R4	Gene names	Abca8a
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 8-A.

CD1D2_MOUSE
NC score	-0.006993 (rank : 3008)	θ value	5.27518 (rank : 2396)
Query Neighborhood Hits	2923	Target Neighborhood Hits	190	Shared Neighborhood Hits	50
SwissProt Accessions	P11610	Gene names	Cd1d2, Cd1.2
Domain Architecture
Description	T-cell surface glycoprotein CD1d2 precursor (CD1.2 antigen).

DDX24_MOUSE
NC score	-0.007085 (rank : 3009)	θ value	6.88961 (rank : 2580)
Query Neighborhood Hits	2923	Target Neighborhood Hits	147	Shared Neighborhood Hits	38
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

PCDAC_HUMAN
NC score	-0.007269 (rank : 3010)	θ value	5.27518 (rank : 2484)
Query Neighborhood Hits	2923	Target Neighborhood Hits	200	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UN75, O75278	Gene names	PCDHA12
Domain Architecture
Description	Protocadherin alpha 12 precursor (PCDH-alpha12).

PCDA5_HUMAN
NC score	-0.007292 (rank : 3011)	θ value	4.03905 (rank : 2329)
Query Neighborhood Hits	2923	Target Neighborhood Hits	217	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y5H7, O75284, Q8N4R3	Gene names	PCDHA5
Domain Architecture
Description	Protocadherin alpha 5 precursor (PCDH-alpha5).

PC11Y_HUMAN
NC score	-0.007303 (rank : 3012)	θ value	0.813845 (rank : 1739)
Query Neighborhood Hits	2923	Target Neighborhood Hits	205	Shared Neighborhood Hits	56
SwissProt Accessions	Q9BZA8, Q70LR6, Q70LR8, Q70LS0, Q70LS1, Q70LS2, Q70LS3, Q70LS4, Q70LS5, Q8WY34, Q9BZA9, Q9H4E1	Gene names	PCDH11Y, PCDH11, PCDH22, PCDHY
Domain Architecture	No domain graphic available
Description	Protocadherin-11 Y-linked precursor (Protocadherin-11) (Protocadherin- 22) (Protocadherin on the Y chromosome) (PCDH-Y) (Protocadherin prostate cancer) (Protocadherin-PC).

DDX49_HUMAN
NC score	-0.007304 (rank : 3013)	θ value	6.88961 (rank : 2581)
Query Neighborhood Hits	2923	Target Neighborhood Hits	223	Shared Neighborhood Hits	82
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

PCDA4_HUMAN
NC score	-0.007366 (rank : 3014)	θ value	5.27518 (rank : 2476)
Query Neighborhood Hits	2923	Target Neighborhood Hits	193	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UN74, O75285	Gene names	PCDHA4
Domain Architecture
Description	Protocadherin alpha 4 precursor (PCDH-alpha4).

PCDA4_MOUSE
NC score	-0.007385 (rank : 3015)	θ value	5.27518 (rank : 2477)
Query Neighborhood Hits	2923	Target Neighborhood Hits	193	Shared Neighborhood Hits	46
SwissProt Accessions	O88689, Q3UEX3, Q6PAM9, Q8K487, Q8K489	Gene names	Pcdha4, Cnr1
Domain Architecture	No domain graphic available
Description	Protocadherin alpha 4 precursor (PCDH-alpha4).

PCDA1_HUMAN
NC score	-0.007391 (rank : 3016)	θ value	5.27518 (rank : 2473)
Query Neighborhood Hits	2923	Target Neighborhood Hits	199	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y5I3, O75288, Q9NRT7	Gene names	PCDHA1
Domain Architecture
Description	Protocadherin alpha 1 precursor (PCDH-alpha1).

PCDA7_HUMAN
NC score	-0.007391 (rank : 3017)	θ value	5.27518 (rank : 2479)
Query Neighborhood Hits	2923	Target Neighborhood Hits	221	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UN72, O75282	Gene names	PCDHA7
Domain Architecture
Description	Protocadherin alpha 7 precursor (PCDH-alpha7).

PCDA3_HUMAN
NC score	-0.007450 (rank : 3018)	θ value	5.27518 (rank : 2475)
Query Neighborhood Hits	2923	Target Neighborhood Hits	203	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y5H8, O75286	Gene names	PCDHA3
Domain Architecture
Description	Protocadherin alpha 3 precursor (PCDH-alpha3).

PCDAA_HUMAN
NC score	-0.007451 (rank : 3019)	θ value	5.27518 (rank : 2482)
Query Neighborhood Hits	2923	Target Neighborhood Hits	183	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y5I2, O75280, Q9NRU2	Gene names	PCDHA10
Domain Architecture
Description	Protocadherin alpha 10 precursor (PCDH-alpha10).

PCDAB_HUMAN
NC score	-0.007467 (rank : 3020)	θ value	5.27518 (rank : 2483)
Query Neighborhood Hits	2923	Target Neighborhood Hits	211	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y5I1, O75279	Gene names	PCDHA11
Domain Architecture
Description	Protocadherin alpha 11 precursor (PCDH-alpha11).

PPP5_HUMAN
NC score	-0.007472 (rank : 3021)	θ value	4.03905 (rank : 2334)
Query Neighborhood Hits	2923	Target Neighborhood Hits	101	Shared Neighborhood Hits	12
SwissProt Accessions	P53041, Q16722	Gene names	PPP5C, PPP5
Domain Architecture
Description	Serine/threonine-protein phosphatase 5 (EC 3.1.3.16) (PP5) (Protein phosphatase T) (PP-T) (PPT).

PCDAD_HUMAN
NC score	-0.007551 (rank : 3022)	θ value	5.27518 (rank : 2485)
Query Neighborhood Hits	2923	Target Neighborhood Hits	197	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y5I0, O75277	Gene names	PCDHA13
Domain Architecture
Description	Protocadherin alpha 13 precursor (PCDH-alpha13).

CSMD2_HUMAN
NC score	-0.007552 (rank : 3023)	θ value	1.81305 (rank : 1923)
Query Neighborhood Hits	2923	Target Neighborhood Hits	188	Shared Neighborhood Hits	25
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

PCDA8_HUMAN
NC score	-0.007569 (rank : 3024)	θ value	5.27518 (rank : 2480)
Query Neighborhood Hits	2923	Target Neighborhood Hits	187	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y5H6, O75281	Gene names	PCDHA8
Domain Architecture
Description	Protocadherin alpha 8 precursor (PCDH-alpha8).

PCDA2_HUMAN
NC score	-0.007645 (rank : 3025)	θ value	5.27518 (rank : 2474)
Query Neighborhood Hits	2923	Target Neighborhood Hits	192	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y5H9, O75287, Q9BTV3	Gene names	PCDHA2
Domain Architecture
Description	Protocadherin alpha 2 precursor (PCDH-alpha2).

PCDA9_HUMAN
NC score	-0.007708 (rank : 3026)	θ value	5.27518 (rank : 2481)
Query Neighborhood Hits	2923	Target Neighborhood Hits	203	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y5H5, O15053	Gene names	PCDHA9, KIAA0345
Domain Architecture
Description	Protocadherin alpha 9 precursor (PCDH-alpha9).

PCDA6_HUMAN
NC score	-0.007744 (rank : 3027)	θ value	5.27518 (rank : 2478)
Query Neighborhood Hits	2923	Target Neighborhood Hits	187	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UN73, O75283, Q9NRT8	Gene names	PCDHA6
Domain Architecture
Description	Protocadherin alpha 6 precursor (PCDH-alpha6).

HXA3_MOUSE
NC score	-0.007791 (rank : 3028)	θ value	4.03905 (rank : 2292)
Query Neighborhood Hits	2923	Target Neighborhood Hits	558	Shared Neighborhood Hits	144
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

FOXO1_MOUSE
NC score	-0.007792 (rank : 3029)	θ value	6.88961 (rank : 2602)
Query Neighborhood Hits	2923	Target Neighborhood Hits	118	Shared Neighborhood Hits	19
SwissProt Accessions	Q9R1E0	Gene names	Foxo1a, Fkhr, Foxo1
Domain Architecture
Description	Forkhead box protein O1A (Forkhead in rhabdomyosarcoma).

MRP5_HUMAN
NC score	-0.007895 (rank : 3030)	θ value	3.0926 (rank : 2192)
Query Neighborhood Hits	2923	Target Neighborhood Hits	110	Shared Neighborhood Hits	11
SwissProt Accessions	O15440, O14517, Q9UN85, Q9UNP5, Q9UQC3	Gene names	ABCC5, MRP5
Domain Architecture
Description	Multidrug resistance-associated protein 5 (ATP-binding cassette sub- family C member 5) (Multi-specific organic anion transporter-C) (MOAT- C) (pABC11) (SMRP).

TREF1_HUMAN
NC score	-0.008132 (rank : 3031)	θ value	6.88961 (rank : 2704)
Query Neighborhood Hits	2923	Target Neighborhood Hits	651	Shared Neighborhood Hits	102
SwissProt Accessions	Q96PN7, Q7Z6T2, Q7Z6T3, Q9NQ72, Q9NQ73, Q9NUN9	Gene names	TRERF1, RAPA, TREP132
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132) (Zinc finger protein rapa).

PCDC2_HUMAN
NC score	-0.008293 (rank : 3032)	θ value	1.81305 (rank : 1965)
Query Neighborhood Hits	2923	Target Neighborhood Hits	185	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y5I4, Q9Y5F4	Gene names	PCDHAC2
Domain Architecture
Description	Protocadherin alpha C2 precursor (PCDH-alpha-C2).

KCNA2_MOUSE
NC score	-0.008300 (rank : 3033)	θ value	6.88961 (rank : 2628)
Query Neighborhood Hits	2923	Target Neighborhood Hits	102	Shared Neighborhood Hits	7
SwissProt Accessions	P63141, P15386, Q02010, Q8C8W4	Gene names	Kcna2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (MK2).

KCNA2_HUMAN
NC score	-0.008302 (rank : 3034)	θ value	6.88961 (rank : 2627)
Query Neighborhood Hits	2923	Target Neighborhood Hits	101	Shared Neighborhood Hits	7
SwissProt Accessions	P16389	Gene names	KCNA2
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (HBK5) (NGK1) (HUKIV).

PCDC1_HUMAN
NC score	-0.008315 (rank : 3035)	θ value	5.27518 (rank : 2486)
Query Neighborhood Hits	2923	Target Neighborhood Hits	181	Shared Neighborhood Hits	41
SwissProt Accessions	Q9H158, Q9Y5F5, Q9Y5I5	Gene names	PCDHAC1
Domain Architecture
Description	Protocadherin alpha C1 precursor (PCDH-alpha-C1).

HXA3_HUMAN
NC score	-0.008374 (rank : 3036)	θ value	3.0926 (rank : 2174)
Query Neighborhood Hits	2923	Target Neighborhood Hits	535	Shared Neighborhood Hits	125
SwissProt Accessions	O43365	Gene names	HOXA3, HOX1E
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1E).

DNJA4_MOUSE
NC score	-0.008399 (rank : 3037)	θ value	8.99809 (rank : 2767)
Query Neighborhood Hits	2923	Target Neighborhood Hits	87	Shared Neighborhood Hits	9
SwissProt Accessions	Q9JMC3, Q543S9, Q9CTD6, Q9CUD4	Gene names	Dnaja4
Domain Architecture
Description	DnaJ homolog subfamily A member 4 (MmDjA4).

PCD19_HUMAN
NC score	-0.008431 (rank : 3038)	θ value	2.36792 (rank : 2089)
Query Neighborhood Hits	2923	Target Neighborhood Hits	164	Shared Neighborhood Hits	34
SwissProt Accessions	Q8TAB3, Q5JTG1, Q5JTG2, Q68DT7, Q9P2N3	Gene names	PCDH19, KIAA1313
Domain Architecture
Description	Protocadherin-19 precursor.

MRP5_MOUSE
NC score	-0.008466 (rank : 3039)	θ value	8.99809 (rank : 2834)
Query Neighborhood Hits	2923	Target Neighborhood Hits	99	Shared Neighborhood Hits	9
SwissProt Accessions	Q9R1X5, O88284	Gene names	Abcc5, Abcc5a, Mrp5
Domain Architecture
Description	Multidrug resistance-associated protein 5 (ATP-binding cassette sub- family C member 5) (ABC transporter MOAT-C) (SMRP).

PO2F1_HUMAN
NC score	-0.008506 (rank : 3040)	θ value	6.88961 (rank : 2673)
Query Neighborhood Hits	2923	Target Neighborhood Hits	426	Shared Neighborhood Hits	55
SwissProt Accessions	P14859, Q5TBT7, Q6PK46, Q8NEU9, Q9BPV1	Gene names	POU2F1, OCT1, OTF1
Domain Architecture
Description	POU domain, class 2, transcription factor 1 (Octamer-binding transcription factor 1) (Oct-1) (OTF-1) (NF-A1).

PCDBE_HUMAN
NC score	-0.008653 (rank : 3041)	θ value	8.99809 (rank : 2850)
Query Neighborhood Hits	2923	Target Neighborhood Hits	154	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y5E9	Gene names	PCDHB14
Domain Architecture
Description	Protocadherin beta 14 precursor (PCDH-beta14).

PCDB3_HUMAN
NC score	-0.008735 (rank : 3042)	θ value	6.88961 (rank : 2668)
Query Neighborhood Hits	2923	Target Neighborhood Hits	159	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y5E6	Gene names	PCDHB3
Domain Architecture
Description	Protocadherin beta 3 precursor (PCDH-beta3).

ABCBB_HUMAN
NC score	-0.008753 (rank : 3043)	θ value	6.88961 (rank : 2544)
Query Neighborhood Hits	2923	Target Neighborhood Hits	103	Shared Neighborhood Hits	12
SwissProt Accessions	O95342, Q9UNB2	Gene names	ABCB11, BSEP
Domain Architecture
Description	Bile salt export pump (ATP-binding cassette sub-family B member 11).

DDX52_HUMAN
NC score	-0.008830 (rank : 3044)	θ value	4.03905 (rank : 2271)
Query Neighborhood Hits	2923	Target Neighborhood Hits	107	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y2R4, Q86YG1, Q8N213, Q9NVE0, Q9Y482	Gene names	DDX52, ROK1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

PCDG1_HUMAN
NC score	-0.008948 (rank : 3045)	θ value	6.88961 (rank : 2669)
Query Neighborhood Hits	2923	Target Neighborhood Hits	158	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y5H4, Q9Y5D6	Gene names	PCDHGA1
Domain Architecture
Description	Protocadherin gamma A1 precursor (PCDH-gamma-A1).

PPIL4_HUMAN
NC score	-0.008970 (rank : 3046)	θ value	8.99809 (rank : 2858)
Query Neighborhood Hits	2923	Target Neighborhood Hits	264	Shared Neighborhood Hits	39
SwissProt Accessions	Q8WUA2, Q7Z3Q5	Gene names	PPIL4
Domain Architecture	No domain graphic available
Description	Peptidyl-prolyl cis-trans isomerase-like 4 (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin-like protein PPIL4).

CAD16_HUMAN
NC score	-0.009066 (rank : 3047)	θ value	6.88961 (rank : 2558)
Query Neighborhood Hits	2923	Target Neighborhood Hits	159	Shared Neighborhood Hits	40
SwissProt Accessions	O75309, Q6UW93	Gene names	CDH16
Domain Architecture
Description	Cadherin-16 precursor (Kidney-specific cadherin) (Ksp-cadherin).

PCDH7_HUMAN
NC score	-0.009081 (rank : 3048)	θ value	8.99809 (rank : 2852)
Query Neighborhood Hits	2923	Target Neighborhood Hits	175	Shared Neighborhood Hits	44
SwissProt Accessions	O60245, O60246, O60247	Gene names	PCDH7, BHPCDH
Domain Architecture
Description	Protocadherin-7 precursor (Brain-heart protocadherin) (BH-Pcdh).

BACH2_HUMAN
NC score	-0.009082 (rank : 3049)	θ value	3.0926 (rank : 2128)
Query Neighborhood Hits	2923	Target Neighborhood Hits	234	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BYV9, Q59H70, Q5T793, Q9NTS5	Gene names	BACH2
Domain Architecture
Description	Transcription regulator protein BACH2 (BTB and CNC homolog 2).

WDTC1_HUMAN
NC score	-0.009141 (rank : 3050)	θ value	0.813845 (rank : 1761)
Query Neighborhood Hits	2923	Target Neighborhood Hits	299	Shared Neighborhood Hits	21
SwissProt Accessions	Q8N5D0, Q9NV87, Q9UPW4	Gene names	WDTC1, KIAA1037
Domain Architecture
Description	WD and tetratricopeptide repeats protein 1.

PCDG9_HUMAN
NC score	-0.009147 (rank : 3051)	θ value	8.99809 (rank : 2851)
Query Neighborhood Hits	2923	Target Neighborhood Hits	158	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y5G4, Q9Y5C9	Gene names	PCDHGA9
Domain Architecture
Description	Protocadherin gamma A9 precursor (PCDH-gamma-A9).

PPIL4_MOUSE
NC score	-0.009425 (rank : 3052)	θ value	8.99809 (rank : 2859)
Query Neighborhood Hits	2923	Target Neighborhood Hits	232	Shared Neighborhood Hits	32
SwissProt Accessions	Q9CXG3, Q3TJX1, Q68FC7, Q9CT22	Gene names	Ppil4
Domain Architecture	No domain graphic available
Description	Peptidyl-prolyl cis-trans isomerase-like 4 (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin-like protein PPIL4).

WDTC1_MOUSE
NC score	-0.009593 (rank : 3053)	θ value	1.38821 (rank : 1897)
Query Neighborhood Hits	2923	Target Neighborhood Hits	298	Shared Neighborhood Hits	21
SwissProt Accessions	Q80ZK9	Gene names	Wdtc1
Domain Architecture
Description	WD and tetratricopeptide repeats protein 1.

GEMI5_MOUSE
NC score	-0.009624 (rank : 3054)	θ value	5.27518 (rank : 2428)
Query Neighborhood Hits	2923	Target Neighborhood Hits	424	Shared Neighborhood Hits	75
SwissProt Accessions	Q8BX17	Gene names	Gemin5
Domain Architecture
Description	Gem-associated protein 5 (Gemin5).

CAD10_HUMAN
NC score	-0.010209 (rank : 3055)	θ value	3.0926 (rank : 2138)
Query Neighborhood Hits	2923	Target Neighborhood Hits	162	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y6N8, Q9ULB3	Gene names	CDH10
Domain Architecture
Description	Cadherin-10 precursor (T2-cadherin).

SCAP_HUMAN
NC score	-0.010321 (rank : 3056)	θ value	8.99809 (rank : 2874)
Query Neighborhood Hits	2923	Target Neighborhood Hits	368	Shared Neighborhood Hits	71
SwissProt Accessions	Q12770, Q8N2E0, Q8WUA1	Gene names	SCAP, KIAA0199
Domain Architecture
Description	Sterol regulatory element-binding protein cleavage-activating protein (SREBP cleavage-activating protein) (SCAP).

DSG1A_MOUSE
NC score	-0.010509 (rank : 3057)	θ value	8.99809 (rank : 2770)
Query Neighborhood Hits	2923	Target Neighborhood Hits	156	Shared Neighborhood Hits	34
SwissProt Accessions	Q61495, Q8CE03	Gene names	Dsg1a, Dsg1
Domain Architecture	No domain graphic available
Description	Desmoglein-1 alpha precursor (Dsg1-alpha) (Desmoglein-1) (Desmosomal glycoprotein I) (DG1) (DGI).

CENG2_MOUSE
NC score	-0.010887 (rank : 3058)	θ value	8.99809 (rank : 2748)
Query Neighborhood Hits	2923	Target Neighborhood Hits	463	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

GP152_MOUSE
NC score	-0.011227 (rank : 3059)	θ value	2.36792 (rank : 2050)
Query Neighborhood Hits	2923	Target Neighborhood Hits	607	Shared Neighborhood Hits	104
SwissProt Accessions	Q8BXS7	Gene names	Gpr152
Domain Architecture
Description	Probable G-protein coupled receptor 152.

ZN512_HUMAN
NC score	-0.011231 (rank : 3060)	θ value	5.27518 (rank : 2536)
Query Neighborhood Hits	2923	Target Neighborhood Hits	444	Shared Neighborhood Hits	39
SwissProt Accessions	Q96ME7, Q96JM0	Gene names	ZNF512, KIAA1805
Domain Architecture	No domain graphic available
Description	Zinc finger protein 512.

FAN_MOUSE
NC score	-0.011353 (rank : 3061)	θ value	2.36792 (rank : 2046)
Query Neighborhood Hits	2923	Target Neighborhood Hits	292	Shared Neighborhood Hits	25
SwissProt Accessions	O35242	Gene names	Nsmaf, Fan
Domain Architecture
Description	Protein FAN (Factor associated with N-SMase activation) (Factor associated with neutral sphingomyelinase activation).

ZN292_HUMAN
NC score	-0.011775 (rank : 3062)	θ value	5.27518 (rank : 2535)
Query Neighborhood Hits	2923	Target Neighborhood Hits	918	Shared Neighborhood Hits	189
SwissProt Accessions	O60281, Q9H8G3, Q9H8J4	Gene names	ZNF292, KIAA0530
Domain Architecture	No domain graphic available
Description	Zinc finger protein 292.

HV3K_HUMAN
NC score	-0.011837 (rank : 3063)	θ value	5.27518 (rank : 2440)
Query Neighborhood Hits	2923	Target Neighborhood Hits	185	Shared Neighborhood Hits	31
SwissProt Accessions	P01772	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V-III region KOL.

KLH13_HUMAN
NC score	-0.011858 (rank : 3064)	θ value	6.88961 (rank : 2631)
Query Neighborhood Hits	2923	Target Neighborhood Hits	193	Shared Neighborhood Hits	19
SwissProt Accessions	Q9P2N7, Q6P2E3, Q96QI7, Q9UDN9	Gene names	KLHL13, BKLHD2, KIAA1309
Domain Architecture
Description	Kelch-like protein 13 (BTB and kelch domain-containing protein 2).

HV05_MOUSE
NC score	-0.012836 (rank : 3065)	θ value	5.27518 (rank : 2439)
Query Neighborhood Hits	2923	Target Neighborhood Hits	256	Shared Neighborhood Hits	51
SwissProt Accessions	P01749	Gene names	Igh-VJ558
Domain Architecture
Description	Ig heavy chain V region 3 precursor.

KLH10_MOUSE
NC score	-0.012907 (rank : 3066)	θ value	8.99809 (rank : 2814)
Query Neighborhood Hits	2923	Target Neighborhood Hits	192	Shared Neighborhood Hits	19
SwissProt Accessions	Q9D5V2, Q8BVM3, Q9DA07	Gene names	Klhl10
Domain Architecture	No domain graphic available
Description	Kelch-like protein 10.

KBTB2_HUMAN
NC score	-0.012968 (rank : 3067)	θ value	6.88961 (rank : 2626)
Query Neighborhood Hits	2923	Target Neighborhood Hits	179	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IY47, Q86Y62, Q9P239, Q9UFM7	Gene names	KBTBD2, BKLHD1, KIAA1489
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 2 (BTB and kelch domain-containing protein 1).

KLH10_HUMAN
NC score	-0.013020 (rank : 3068)	θ value	8.99809 (rank : 2813)
Query Neighborhood Hits	2923	Target Neighborhood Hits	194	Shared Neighborhood Hits	18
SwissProt Accessions	Q6JEL2, Q6NW28, Q96MC0	Gene names	KLHL10
Domain Architecture	No domain graphic available
Description	Kelch-like protein 10.

WDR18_MOUSE
NC score	-0.013289 (rank : 3069)	θ value	6.88961 (rank : 2709)
Query Neighborhood Hits	2923	Target Neighborhood Hits	239	Shared Neighborhood Hits	17
SwissProt Accessions	Q4VBE8	Gene names	Wdr18
Domain Architecture	No domain graphic available
Description	WD repeat protein 18.

LHX4_MOUSE
NC score	-0.013611 (rank : 3070)	θ value	3.0926 (rank : 2186)
Query Neighborhood Hits	2923	Target Neighborhood Hits	457	Shared Neighborhood Hits	30
SwissProt Accessions	P53776, O08916, Q9R280	Gene names	Lhx4, Gsh-4, Gsh4
Domain Architecture
Description	LIM/homeobox protein Lhx4.

LHX4_HUMAN
NC score	-0.013738 (rank : 3071)	θ value	4.03905 (rank : 2306)
Query Neighborhood Hits	2923	Target Neighborhood Hits	455	Shared Neighborhood Hits	30
SwissProt Accessions	Q969G2, Q8NHE0, Q8TCJ1, Q8WWX2, Q969W2	Gene names	LHX4
Domain Architecture
Description	LIM/homeobox protein Lhx4.

ACRO_HUMAN
NC score	-0.013952 (rank : 3072)	θ value	8.99809 (rank : 2722)
Query Neighborhood Hits	2923	Target Neighborhood Hits	291	Shared Neighborhood Hits	73
SwissProt Accessions	P10323, Q6ICK2	Gene names	ACR, ACRS
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

HXB5_MOUSE
NC score	-0.014263 (rank : 3073)	θ value	0.0563607 (rank : 1312)
Query Neighborhood Hits	2923	Target Neighborhood Hits	337	Shared Neighborhood Hits	26
SwissProt Accessions	P09079, Q3ZAY8	Gene names	Hoxb5, Hox-2.1, Hoxb-5
Domain Architecture
Description	Homeobox protein Hox-B5 (Hox-2.1) (MU-1) (H24.1).

HXB5_HUMAN
NC score	-0.014661 (rank : 3074)	θ value	0.0736092 (rank : 1335)
Query Neighborhood Hits	2923	Target Neighborhood Hits	332	Shared Neighborhood Hits	22
SwissProt Accessions	P09067, P09069	Gene names	HOXB5, HOX2A
Domain Architecture
Description	Homeobox protein Hox-B5 (Hox-2A) (HHO.C10) (HU-1).

AAMP_HUMAN
NC score	-0.015261 (rank : 3075)	θ value	6.88961 (rank : 2543)
Query Neighborhood Hits	2923	Target Neighborhood Hits	294	Shared Neighborhood Hits	18
SwissProt Accessions	Q13685, Q8WUJ9, Q96H92	Gene names	AAMP
Domain Architecture
Description	Angio-associated migratory cell protein.

TBLX_MOUSE
NC score	-0.016204 (rank : 3076)	θ value	0.813845 (rank : 1751)
Query Neighborhood Hits	2923	Target Neighborhood Hits	335	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QXE7, Q8BMM0, Q8BYQ4, Q8C0A1	Gene names	Tbl1x, Tbl1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1X (Transducin beta-like 1X protein).

TBL1Y_HUMAN
NC score	-0.016313 (rank : 3077)	θ value	1.81305 (rank : 1992)
Query Neighborhood Hits	2923	Target Neighborhood Hits	331	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BQ87	Gene names	TBL1Y, TBL1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1Y (Transducin beta-like 1Y protein) (Transducin-beta-like 1, Y-linked).

KLK1_HUMAN
NC score	-0.017037 (rank : 3078)	θ value	6.88961 (rank : 2632)
Query Neighborhood Hits	2923	Target Neighborhood Hits	183	Shared Neighborhood Hits	8
SwissProt Accessions	P06870, Q8TCV8, Q9BS53, Q9NQU4, Q9UMJ1	Gene names	KLK1
Domain Architecture
Description	Kallikrein-1 precursor (EC 3.4.21.35) (Tissue kallikrein) (Kidney/pancreas/salivary gland kallikrein).

KTNB1_MOUSE
NC score	-0.017993 (rank : 3079)	θ value	5.27518 (rank : 2447)
Query Neighborhood Hits	2923	Target Neighborhood Hits	356	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BG40, Q8CD18, Q8R1J0, Q9CWV2	Gene names	Katnb1
Domain Architecture	No domain graphic available
Description	Katanin p80 WD40-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin).

ZEP2_MOUSE
NC score	-0.018794 (rank : 3080)	θ value	0.47712 (rank : 1644)
Query Neighborhood Hits	2923	Target Neighborhood Hits	964	Shared Neighborhood Hits	163
SwissProt Accessions	Q3UHF7, O55140, Q3UVD4, Q3UVH5	Gene names	Hivep2, Mibp1
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 homolog (Myc intron-binding protein 1) (MIBP-1).

ARX_HUMAN
NC score	-0.019755 (rank : 3081)	θ value	8.99809 (rank : 2732)
Query Neighborhood Hits	2923	Target Neighborhood Hits	401	Shared Neighborhood Hits	38
SwissProt Accessions	Q96QS3	Gene names	ARX
Domain Architecture
Description	Homeobox protein ARX (Aristaless-related homeobox).

ZEP2_HUMAN
NC score	-0.020436 (rank : 3082)	θ value	8.99809 (rank : 2917)
Query Neighborhood Hits	2923	Target Neighborhood Hits	937	Shared Neighborhood Hits	158
SwissProt Accessions	P31629, Q02646, Q5THT5, Q9NS05	Gene names	HIVEP2
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 (HIV- EP2) (MHC-binding protein 2) (MBP-2).

ZN438_HUMAN
NC score	-0.022199 (rank : 3083)	θ value	1.38821 (rank : 1899)
Query Neighborhood Hits	2923	Target Neighborhood Hits	906	Shared Neighborhood Hits	140
SwissProt Accessions	Q7Z4V0, Q5T426, Q658Q4, Q6ZN65	Gene names	ZNF438
Domain Architecture	No domain graphic available
Description	Zinc finger protein 438.

ZN516_MOUSE
NC score	-0.022251 (rank : 3084)	θ value	0.365318 (rank : 1579)
Query Neighborhood Hits	2923	Target Neighborhood Hits	1197	Shared Neighborhood Hits	225
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

POGZ_MOUSE
NC score	-0.022662 (rank : 3085)	θ value	8.99809 (rank : 2857)
Query Neighborhood Hits	2923	Target Neighborhood Hits	765	Shared Neighborhood Hits	105
SwissProt Accessions	Q8BZH4, Q4VA94, Q80TZ8, Q8C0K1, Q8K294	Gene names	Pogz, Kiaa0461
Domain Architecture
Description	Pogo transposable element with ZNF domain.

FOG2_MOUSE
NC score	-0.022744 (rank : 3086)	θ value	3.0926 (rank : 2171)
Query Neighborhood Hits	2923	Target Neighborhood Hits	714	Shared Neighborhood Hits	68
SwissProt Accessions	Q8CCH7, Q9Z0F2	Gene names	Zfpm2, Fog2
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM2 (Zinc finger protein multitype 2) (Friend of GATA protein 2) (Friend of GATA-2) (FOG-2) (mFOG-2).

FOG2_HUMAN
NC score	-0.023012 (rank : 3087)	θ value	3.0926 (rank : 2170)
Query Neighborhood Hits	2923	Target Neighborhood Hits	731	Shared Neighborhood Hits	70
SwissProt Accessions	Q8WW38, Q9NPL7, Q9NPS4, Q9UNI5	Gene names	ZFPM2, FOG2
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM2 (Zinc finger protein multitype 2) (Friend of GATA protein 2) (FOG-2) (hFOG-2).

ZN217_HUMAN
NC score	-0.023601 (rank : 3088)	θ value	0.813845 (rank : 1763)
Query Neighborhood Hits	2923	Target Neighborhood Hits	905	Shared Neighborhood Hits	142
SwissProt Accessions	O75362	Gene names	ZNF217, ZABC1
Domain Architecture	No domain graphic available
Description	Zinc finger protein 217.

P2Y14_MOUSE
NC score	-0.024357 (rank : 3089)	θ value	3.0926 (rank : 2203)
Query Neighborhood Hits	2923	Target Neighborhood Hits	520	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ESG6	Gene names	P2ry14, Gpr105
Domain Architecture
Description	P2Y purinoceptor 14 (P2Y14) (UDP-glucose receptor) (G-protein coupled receptor 105).

GP176_MOUSE
NC score	-0.024467 (rank : 3090)	θ value	4.03905 (rank : 2286)
Query Neighborhood Hits	2923	Target Neighborhood Hits	539	Shared Neighborhood Hits	16
SwissProt Accessions	Q80WT4, Q80UC4	Gene names	Gpr176, Agr9, Gm1012
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 176 (G-protein coupled receptor AGR9).

SUHW2_HUMAN
NC score	-0.025336 (rank : 3091)	θ value	1.81305 (rank : 1989)
Query Neighborhood Hits	2923	Target Neighborhood Hits	683	Shared Neighborhood Hits	60
SwissProt Accessions	Q86YH2	Gene names	SUHW2, ZNF632
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 2 (5'OY11.1) (Zinc finger protein 632).

ZBTB9_MOUSE
NC score	-0.026129 (rank : 3092)	θ value	1.81305 (rank : 2008)
Query Neighborhood Hits	2923	Target Neighborhood Hits	780	Shared Neighborhood Hits	68
SwissProt Accessions	Q8CDC7, Q3U3B2, Q9CYQ0	Gene names	Zbtb9
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 9.

RLF_HUMAN
NC score	-0.026623 (rank : 3093)	θ value	8.99809 (rank : 2868)
Query Neighborhood Hits	2923	Target Neighborhood Hits	775	Shared Neighborhood Hits	79
SwissProt Accessions	Q13129, Q9NU60	Gene names	RLF
Domain Architecture	No domain graphic available
Description	Zinc finger protein Rlf (Rearranged L-myc fusion gene protein) (Zn-15- related protein).

GLIS3_MOUSE
NC score	-0.026840 (rank : 3094)	θ value	5.27518 (rank : 2429)
Query Neighborhood Hits	2923	Target Neighborhood Hits	861	Shared Neighborhood Hits	116
SwissProt Accessions	Q6XP49, Q8BI60	Gene names	Glis3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS3 (GLI-similar 3).

BCL6_MOUSE
NC score	-0.027155 (rank : 3095)	θ value	0.00134147 (rank : 1092)
Query Neighborhood Hits	2923	Target Neighborhood Hits	913	Shared Neighborhood Hits	126
SwissProt Accessions	P41183, Q61065	Gene names	Bcl6, Bcl-6
Domain Architecture
Description	B-cell lymphoma 6 protein homolog.

ZN639_HUMAN
NC score	-0.027453 (rank : 3096)	θ value	5.27518 (rank : 2538)
Query Neighborhood Hits	2923	Target Neighborhood Hits	723	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UID6	Gene names	ZNF639, ZASC1
Domain Architecture	No domain graphic available
Description	Zinc finger protein 639 (Zinc finger protein ZASC1) (Zinc finger protein ANC_2H01).

ZN688_HUMAN
NC score	-0.027727 (rank : 3097)	θ value	0.279714 (rank : 1530)
Query Neighborhood Hits	2923	Target Neighborhood Hits	873	Shared Neighborhood Hits	134
SwissProt Accessions	Q8WV14, O75701, Q8IW91, Q96MN0	Gene names	ZNF688
Domain Architecture	No domain graphic available
Description	Zinc finger protein 688.

BCL6_HUMAN
NC score	-0.027759 (rank : 3098)	θ value	0.0431538 (rank : 1280)
Query Neighborhood Hits	2923	Target Neighborhood Hits	922	Shared Neighborhood Hits	123
SwissProt Accessions	P41182	Gene names	BCL6, BCL5, LAZ3, ZBTB27, ZNF51
Domain Architecture
Description	B-cell lymphoma 6 protein (BCL-6) (Zinc finger protein 51) (LAZ-3 protein) (BCL-5) (Zinc finger and BTB domain-containing protein 27).

ZN710_HUMAN
NC score	-0.028172 (rank : 3099)	θ value	0.279714 (rank : 1531)
Query Neighborhood Hits	2923	Target Neighborhood Hits	796	Shared Neighborhood Hits	84
SwissProt Accessions	Q8N1W2, Q6ZMK9, Q8NDU0	Gene names	ZNF710
Domain Architecture	No domain graphic available
Description	Zinc finger protein 710.

ZN406_MOUSE
NC score	-0.028424 (rank : 3100)	θ value	0.365318 (rank : 1578)
Query Neighborhood Hits	2923	Target Neighborhood Hits	800	Shared Neighborhood Hits	83
SwissProt Accessions	Q7TS63	Gene names	Znf406, Zfp406
Domain Architecture	No domain graphic available
Description	Zinc finger protein 406.

PRD15_HUMAN
NC score	-0.028613 (rank : 3101)	θ value	1.06291 (rank : 1804)
Query Neighborhood Hits	2923	Target Neighborhood Hits	805	Shared Neighborhood Hits	89
SwissProt Accessions	P57071, Q8N0X3, Q8NEX0, Q9NQV3	Gene names	PRDM15, C21orf83, ZNF298
Domain Architecture
Description	PR domain zinc finger protein 15 (PR domain-containing protein 15) (Zinc finger protein 298).

ZSCA5_HUMAN
NC score	-0.028654 (rank : 3102)	θ value	3.0926 (rank : 2245)
Query Neighborhood Hits	2923	Target Neighborhood Hits	862	Shared Neighborhood Hits	124
SwissProt Accessions	Q9BUG6	Gene names	ZSCAN5, ZNF495
Domain Architecture	No domain graphic available
Description	Zinc finger and SCAN domain-containing protein 5 (Zinc finger protein 495).

ZN358_HUMAN
NC score	-0.028716 (rank : 3103)	θ value	8.99809 (rank : 2922)
Query Neighborhood Hits	2923	Target Neighborhood Hits	840	Shared Neighborhood Hits	113
SwissProt Accessions	Q9NW07, Q9BTM7	Gene names	ZNF358
Domain Architecture
Description	Zinc finger protein 358.

ZN206_HUMAN
NC score	-0.028879 (rank : 3104)	θ value	1.38821 (rank : 1898)
Query Neighborhood Hits	2923	Target Neighborhood Hits	853	Shared Neighborhood Hits	109
SwissProt Accessions	Q96SZ4	Gene names	ZNF206, ZSCAN10
Domain Architecture	No domain graphic available
Description	Zinc finger protein 206 (Zinc finger and SCAN domain-containing protein 10).

GLI1_MOUSE
NC score	-0.028984 (rank : 3105)	θ value	4.03905 (rank : 2284)
Query Neighborhood Hits	2923	Target Neighborhood Hits	785	Shared Neighborhood Hits	85
SwissProt Accessions	P47806, Q9QYK1	Gene names	Gli1, Gli
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI1 (Glioma-associated oncogene homolog).

ZFY1_MOUSE
NC score	-0.029065 (rank : 3106)	θ value	6.88961 (rank : 2713)
Query Neighborhood Hits	2923	Target Neighborhood Hits	790	Shared Neighborhood Hits	81
SwissProt Accessions	P10925	Gene names	Zfy1, Zfy-1
Domain Architecture
Description	Zinc finger Y-chromosomal protein 1.

ZFP95_HUMAN
NC score	-0.029075 (rank : 3107)	θ value	0.0193708 (rank : 1250)
Query Neighborhood Hits	2923	Target Neighborhood Hits	775	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y2L8	Gene names	ZFP95, KIAA1015
Domain Architecture
Description	Zinc finger protein 95 homolog (Zfp-95).

TCF17_HUMAN
NC score	-0.029209 (rank : 3108)	θ value	5.27518 (rank : 2524)
Query Neighborhood Hits	2923	Target Neighborhood Hits	797	Shared Neighborhood Hits	83
SwissProt Accessions	O60765, Q9UNJ8	Gene names	ZNF354A, EZNF, HKL1, TCF17
Domain Architecture
Description	Zinc finger protein 354A (Transcription factor 17) (Zinc finger protein eZNF).

KAISO_MOUSE
NC score	-0.029223 (rank : 3109)	θ value	6.88961 (rank : 2625)
Query Neighborhood Hits	2923	Target Neighborhood Hits	821	Shared Neighborhood Hits	84
SwissProt Accessions	Q8BN78, Q8C226, Q9WTZ7	Gene names	Zbtb33, Kaiso
Domain Architecture	No domain graphic available
Description	Transcriptional regulator Kaiso (Zinc finger and BTB domain-containing protein 33).

ZN509_MOUSE
NC score	-0.029293 (rank : 3110)	θ value	2.36792 (rank : 2123)
Query Neighborhood Hits	2923	Target Neighborhood Hits	990	Shared Neighborhood Hits	147
SwissProt Accessions	Q8BXX2, Q8CID4, Q8K2Z6	Gene names	Znf509, Zfp509
Domain Architecture	No domain graphic available
Description	Zinc finger protein 509.

KLF8_HUMAN
NC score	-0.029598 (rank : 3111)	θ value	5.27518 (rank : 2446)
Query Neighborhood Hits	2923	Target Neighborhood Hits	704	Shared Neighborhood Hits	65
SwissProt Accessions	O95600, Q59GV5, Q5HYQ5, Q5JXP7, Q6MZJ7, Q9UGC4	Gene names	KLF8, BKLF3, ZNF741
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 8 (Basic krueppel-like factor 3) (Zinc finger protein 741).

ZN232_HUMAN
NC score	-0.029600 (rank : 3112)	θ value	3.0926 (rank : 2244)
Query Neighborhood Hits	2923	Target Neighborhood Hits	754	Shared Neighborhood Hits	75
SwissProt Accessions	Q9UNY5	Gene names	ZNF232, ZSCAN11
Domain Architecture
Description	Zinc finger protein 232 (Zinc finger and SCAN domain-containing protein 11).

TIEG3_MOUSE
NC score	-0.029678 (rank : 3113)	θ value	6.88961 (rank : 2699)
Query Neighborhood Hits	2923	Target Neighborhood Hits	774	Shared Neighborhood Hits	85
SwissProt Accessions	Q8K1S5, Q8BI37	Gene names	Tieg3, Tieg2b
Domain Architecture
Description	Transforming growth factor-beta-inducible early growth response protein 3 (TGFB-inducible early growth response protein 3) (TIEG-3) (TGFB-inducible early growth response protein 2b).

ZN214_HUMAN
NC score	-0.029707 (rank : 3114)	θ value	6.88961 (rank : 2716)
Query Neighborhood Hits	2923	Target Neighborhood Hits	748	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UL59	Gene names	ZNF214, BAZ1
Domain Architecture
Description	Zinc finger protein 214 (BWSCR2-associated zinc-finger protein 1) (BAZ 1).

ZN226_HUMAN
NC score	-0.029712 (rank : 3115)	θ value	5.27518 (rank : 2533)
Query Neighborhood Hits	2923	Target Neighborhood Hits	770	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NYT6, Q96TE6, Q9NS44	Gene names	ZNF226
Domain Architecture
Description	Zinc finger protein 226.

ZN143_MOUSE
NC score	-0.029954 (rank : 3116)	θ value	4.03905 (rank : 2368)
Query Neighborhood Hits	2923	Target Neighborhood Hits	718	Shared Neighborhood Hits	65
SwissProt Accessions	O70230	Gene names	Znf143, Staf, Zfp143
Domain Architecture	No domain graphic available
Description	Zinc finger protein 143 (Zfp-143) (Selenocysteine tRNA gene transcription-activating factor) (mStaf).

ZFP30_HUMAN
NC score	-0.029991 (rank : 3117)	θ value	5.27518 (rank : 2532)
Query Neighborhood Hits	2923	Target Neighborhood Hits	742	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y2G7, Q58EY8	Gene names	ZFP30, KIAA0961, ZNF745
Domain Architecture	No domain graphic available
Description	Zinc finger protein 30 homolog (Zfp-30) (Zinc finger protein 745).

ZNF7_HUMAN
NC score	-0.030015 (rank : 3118)	θ value	4.03905 (rank : 2369)
Query Neighborhood Hits	2923	Target Neighborhood Hits	770	Shared Neighborhood Hits	71
SwissProt Accessions	P17097, P17015	Gene names	ZNF7, KOX4
Domain Architecture
Description	Zinc finger protein 7 (Zinc finger protein KOX4) (Zinc finger protein HF.16).

ZNF76_HUMAN
NC score	-0.030079 (rank : 3119)	θ value	8.99809 (rank : 2923)
Query Neighborhood Hits	2923	Target Neighborhood Hits	728	Shared Neighborhood Hits	66
SwissProt Accessions	P36508, Q9BQB2	Gene names	ZNF76
Domain Architecture	No domain graphic available
Description	Zinc finger protein 76.

ZN571_HUMAN
NC score	-0.030082 (rank : 3120)	θ value	5.27518 (rank : 2537)
Query Neighborhood Hits	2923	Target Neighborhood Hits	755	Shared Neighborhood Hits	62
SwissProt Accessions	Q7Z3V5, Q3ZCU3, Q9NZX7	Gene names	ZNF571
Domain Architecture	No domain graphic available
Description	Zinc finger protein 571.

ZN175_HUMAN
NC score	-0.030095 (rank : 3121)	θ value	8.99809 (rank : 2920)
Query Neighborhood Hits	2923	Target Neighborhood Hits	774	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Y473	Gene names	ZNF175
Domain Architecture
Description	Zinc finger protein 175 (Zinc finger protein OTK18).

ZN282_HUMAN
NC score	-0.030144 (rank : 3122)	θ value	5.27518 (rank : 2534)
Query Neighborhood Hits	2923	Target Neighborhood Hits	796	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UDV7, O43691, Q6DKK0	Gene names	ZNF282, HUB1
Domain Architecture
Description	Zinc finger protein 282 (HTLV-I U5RE-binding protein 1) (HUB-1).

ZSCA2_HUMAN
NC score	-0.030150 (rank : 3123)	θ value	5.27518 (rank : 2540)
Query Neighborhood Hits	2923	Target Neighborhood Hits	803	Shared Neighborhood Hits	80
SwissProt Accessions	Q7Z7L9, Q6ZQY9, Q9NWU4	Gene names	ZSCAN2, ZFP29
Domain Architecture	No domain graphic available
Description	Zinc finger and SCAN domain-containing protein 2 (Zinc finger protein 29 homolog) (Zfp-29).

ZN449_HUMAN
NC score	-0.030271 (rank : 3124)	θ value	6.88961 (rank : 2718)
Query Neighborhood Hits	2923	Target Neighborhood Hits	758	Shared Neighborhood Hits	73
SwissProt Accessions	Q6P9G9, Q5JRZ8, Q6NZX2, Q8N3Q1, Q8TED7	Gene names	ZNF449, ZSCAN19
Domain Architecture	No domain graphic available
Description	Zinc finger protein 449 (Zinc finger and SCAN domain-containing protein 19).

ZN200_HUMAN
NC score	-0.030512 (rank : 3125)	θ value	8.99809 (rank : 2921)
Query Neighborhood Hits	2923	Target Neighborhood Hits	720	Shared Neighborhood Hits	63
SwissProt Accessions	P98182, O15361	Gene names	ZNF200, ZNFMF
Domain Architecture
Description	Zinc finger protein 200.

ZBT26_HUMAN
NC score	-0.030585 (rank : 3126)	θ value	1.81305 (rank : 2007)
Query Neighborhood Hits	2923	Target Neighborhood Hits	784	Shared Neighborhood Hits	68
SwissProt Accessions	Q9HCK0, Q8WTR1	Gene names	ZBTB26, KIAA1572, ZNF481
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 26 (Zinc finger protein 481) (Zinc finger protein Bioref).

ZBT39_HUMAN
NC score	-0.030609 (rank : 3127)	θ value	2.36792 (rank : 2121)
Query Neighborhood Hits	2923	Target Neighborhood Hits	805	Shared Neighborhood Hits	62
SwissProt Accessions	O15060	Gene names	ZBTB39, KIAA0352
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 39.

ZF161_HUMAN
NC score	-0.031722 (rank : 3128)	θ value	3.0926 (rank : 2242)
Query Neighborhood Hits	2923	Target Neighborhood Hits	822	Shared Neighborhood Hits	66
SwissProt Accessions	O43829, O00403	Gene names	ZFP161, ZBTB14
Domain Architecture
Description	Zinc finger protein 161 homolog (Zfp-161) (Zinc finger protein 5) (hZF5) (Zinc finger and BTB domain-containing protein 14).

ZF161_MOUSE
NC score	-0.031736 (rank : 3129)	θ value	3.0926 (rank : 2243)
Query Neighborhood Hits	2923	Target Neighborhood Hits	821	Shared Neighborhood Hits	66
SwissProt Accessions	Q08376	Gene names	Zfp161, Zfp-5, Zfp5
Domain Architecture
Description	Zinc finger protein 161 (Zfp-161) (Zinc finger protein 5) (ZF5).

MC4R_MOUSE
NC score	-0.033796 (rank : 3130)	θ value	8.99809 (rank : 2830)
Query Neighborhood Hits	2923	Target Neighborhood Hits	816	Shared Neighborhood Hits	5
SwissProt Accessions	P56450, Q9EQM7	Gene names	Mc4r
Domain Architecture
Description	Melanocortin receptor 4 (MC4-R).

MC4R_HUMAN
NC score	-0.034074 (rank : 3131)	θ value	8.99809 (rank : 2829)
Query Neighborhood Hits	2923	Target Neighborhood Hits	828	Shared Neighborhood Hits	5
SwissProt Accessions	P32245, Q16317, Q3MIJ6	Gene names	MC4R
Domain Architecture
Description	Melanocortin receptor 4 (MC4-R).