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Network neighborhood for query Sequence : JHD3B_MOUSE

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JHD3B_MOUSE
SwissProt Accessions	Q91VY5, Q3UR22, Q6ZQ30, Q99K42	Gene names	Jmjd2b, Jhdm3b
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

JHD3B_HUMAN
θ value	0 (rank : 1)	NC score	0.989189 (rank : 2)
Query Neighborhood Hits	152	Target Neighborhood Hits	128	Shared Neighborhood Hits	71
SwissProt Accessions	O94953, O75274, Q6P3R5, Q9P1V1, Q9UF40	Gene names	JMJD2B, JHDM3B, KIAA0876
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

JHD3B_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	152	Target Neighborhood Hits	152	Shared Neighborhood Hits	152
SwissProt Accessions	Q91VY5, Q3UR22, Q6ZQ30, Q99K42	Gene names	Jmjd2b, Jhdm3b
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

JHD3C_HUMAN
θ value	2.48205e-183 (rank : 3)	NC score	0.967882 (rank : 5)
Query Neighborhood Hits	152	Target Neighborhood Hits	91	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H3R0, O94877, Q2M3M0, Q5JUC9, Q5VYJ2, Q5VYJ3	Gene names	JMJD2C, GASC1, JHDM3C, KIAA0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C) (Gene amplified in squamous cell carcinoma 1 protein) (GASC-1 protein).

JHD3C_MOUSE
θ value	1.36195e-181 (rank : 4)	NC score	0.970555 (rank : 3)
Query Neighborhood Hits	152	Target Neighborhood Hits	84	Shared Neighborhood Hits	48
SwissProt Accessions	Q8VCD7, Q3UNP7, Q69ZZ5, Q8BUY6, Q8BWA1	Gene names	Jmjd2c, Jhdm3c, Kiaa0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C).

JHD3A_HUMAN
θ value	1.36511e-173 (rank : 5)	NC score	0.968156 (rank : 4)
Query Neighborhood Hits	152	Target Neighborhood Hits	78	Shared Neighborhood Hits	45
SwissProt Accessions	O75164, Q5VVB1	Gene names	JMJD2A, JHDM3A, JMJD2, KIAA0677
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3A (EC 1.14.11.-) (Jumonji domain-containing protein 2A).

JHD3A_MOUSE
θ value	1.78289e-173 (rank : 6)	NC score	0.967851 (rank : 6)
Query Neighborhood Hits	152	Target Neighborhood Hits	85	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BW72, Q3UKM5, Q3UM81, Q3UWV2, Q6ZQ72, Q8K137	Gene names	Jmjd2a, Jhdm3a, Jmjd2, Kiaa0677
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3A (EC 1.14.11.-) (Jumonji domain-containing protein 2A).

JHD3D_HUMAN
θ value	1.19867e-161 (rank : 7)	NC score	0.873684 (rank : 8)
Query Neighborhood Hits	152	Target Neighborhood Hits	47	Shared Neighborhood Hits	16
SwissProt Accessions	Q6B0I6, Q9NT41, Q9NW76	Gene names	JMJD2D, JHDM3D
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3D (EC 1.14.11.-) (Jumonji domain-containing protein 2D).

JHD3D_MOUSE
θ value	5.94893e-161 (rank : 8)	NC score	0.875325 (rank : 7)
Query Neighborhood Hits	152	Target Neighborhood Hits	20	Shared Neighborhood Hits	16
SwissProt Accessions	Q3U2K5, Q2M1G7, Q8BI19	Gene names	Jmjd2d, Jhdm3d
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3D (EC 1.14.11.-) (Jumonji domain-containing protein 2D).

JAD1A_HUMAN
θ value	1.24399e-33 (rank : 9)	NC score	0.614736 (rank : 13)
Query Neighborhood Hits	152	Target Neighborhood Hits	328	Shared Neighborhood Hits	42
SwissProt Accessions	P29375	Gene names	JARID1A, RBBP2, RBP2
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1A (Retinoblastoma-binding protein 2) (RBBP-2).

JAD1D_HUMAN
θ value	7.54701e-31 (rank : 10)	NC score	0.617957 (rank : 12)
Query Neighborhood Hits	152	Target Neighborhood Hits	147	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BY66, Q92509, Q92809, Q9HCU1	Gene names	SMCY, HY, HYA, JARID1D, KIAA0234
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

JAD1D_MOUSE
θ value	7.54701e-31 (rank : 11)	NC score	0.605706 (rank : 18)
Query Neighborhood Hits	152	Target Neighborhood Hits	228	Shared Neighborhood Hits	41
SwissProt Accessions	Q62240, Q9QVR9, Q9R040	Gene names	Smcy, Hya, Jarid1d
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

JAD1C_HUMAN
θ value	9.8567e-31 (rank : 12)	NC score	0.606681 (rank : 17)
Query Neighborhood Hits	152	Target Neighborhood Hits	187	Shared Neighborhood Hits	39
SwissProt Accessions	P41229	Gene names	SMCX, DXS1272E, JARID1C, XE169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (Protein SmcX) (Protein Xe169).

JAD1C_MOUSE
θ value	9.8567e-31 (rank : 13)	NC score	0.607318 (rank : 16)
Query Neighborhood Hits	152	Target Neighborhood Hits	164	Shared Neighborhood Hits	38
SwissProt Accessions	P41230, O54995, Q9CVI4, Q9D0C3, Q9QVR8, Q9R039	Gene names	Smcx, Jarid1c, Xe169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (SmcX protein) (Xe169 protein).

BRPF1_HUMAN
θ value	5.40856e-29 (rank : 14)	NC score	0.605685 (rank : 19)
Query Neighborhood Hits	152	Target Neighborhood Hits	259	Shared Neighborhood Hits	57
SwissProt Accessions	P55201, Q9UHI0	Gene names	BRPF1, BR140
Domain Architecture
Description	Peregrin (Bromodomain and PHD finger-containing protein 1) (BR140 protein).

BRD1_HUMAN
θ value	4.57862e-28 (rank : 15)	NC score	0.590690 (rank : 24)
Query Neighborhood Hits	152	Target Neighborhood Hits	188	Shared Neighborhood Hits	46
SwissProt Accessions	O95696	Gene names	BRD1, BRL, BRPF2
Domain Architecture
Description	Bromodomain-containing protein 1 (BR140-like protein).

BRPF3_HUMAN
θ value	4.73814e-25 (rank : 16)	NC score	0.572642 (rank : 26)
Query Neighborhood Hits	152	Target Neighborhood Hits	217	Shared Neighborhood Hits	49
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

AF17_HUMAN
θ value	4.01107e-24 (rank : 17)	NC score	0.677251 (rank : 9)
Query Neighborhood Hits	152	Target Neighborhood Hits	230	Shared Neighborhood Hits	60
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

AF10_HUMAN
θ value	2.59989e-23 (rank : 18)	NC score	0.638133 (rank : 11)
Query Neighborhood Hits	152	Target Neighborhood Hits	198	Shared Neighborhood Hits	43
SwissProt Accessions	P55197	Gene names	MLLT10, AF10
Domain Architecture
Description	Protein AF-10.

AF10_MOUSE
θ value	2.59989e-23 (rank : 19)	NC score	0.640616 (rank : 10)
Query Neighborhood Hits	152	Target Neighborhood Hits	182	Shared Neighborhood Hits	44
SwissProt Accessions	O54826	Gene names	Mllt10, Af10
Domain Architecture
Description	Protein AF-10.

JADE1_HUMAN
θ value	3.75424e-22 (rank : 20)	NC score	0.604385 (rank : 20)
Query Neighborhood Hits	152	Target Neighborhood Hits	140	Shared Neighborhood Hits	45
SwissProt Accessions	Q6IE81, Q4W5D5, Q6ZSL7, Q8NC41, Q96JL8, Q96SQ1, Q9H692	Gene names	PHF17, JADE1, KIAA1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

JADE1_MOUSE
θ value	3.75424e-22 (rank : 21)	NC score	0.603519 (rank : 21)
Query Neighborhood Hits	152	Target Neighborhood Hits	160	Shared Neighborhood Hits	45
SwissProt Accessions	Q6ZPI0, Q6IE84, Q8C7S6, Q8CFM2, Q8R362	Gene names	Phf17, Jade1, Kiaa1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

JADE2_MOUSE
θ value	3.75424e-22 (rank : 22)	NC score	0.572233 (rank : 27)
Query Neighborhood Hits	152	Target Neighborhood Hits	560	Shared Neighborhood Hits	70
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

JADE2_HUMAN
θ value	4.9032e-22 (rank : 23)	NC score	0.602935 (rank : 22)
Query Neighborhood Hits	152	Target Neighborhood Hits	199	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

JADE3_HUMAN
θ value	1.09232e-21 (rank : 24)	NC score	0.608137 (rank : 14)
Query Neighborhood Hits	152	Target Neighborhood Hits	148	Shared Neighborhood Hits	47
SwissProt Accessions	Q92613, Q6IE79	Gene names	PHF16, JADE3, KIAA0215
Domain Architecture
Description	Protein Jade-3 (PHD finger protein 16).

JADE3_MOUSE
θ value	1.09232e-21 (rank : 25)	NC score	0.607860 (rank : 15)
Query Neighborhood Hits	152	Target Neighborhood Hits	174	Shared Neighborhood Hits	47
SwissProt Accessions	Q6IE82, Q6ZQG2	Gene names	Phf16, Jade3, Kiaa0215
Domain Architecture	No domain graphic available
Description	Protein Jade-3 (PHD finger protein 16).

PHF14_HUMAN
θ value	7.32683e-18 (rank : 26)	NC score	0.582885 (rank : 25)
Query Neighborhood Hits	152	Target Neighborhood Hits	447	Shared Neighborhood Hits	52
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

PHF14_MOUSE
θ value	7.32683e-18 (rank : 27)	NC score	0.593763 (rank : 23)
Query Neighborhood Hits	152	Target Neighborhood Hits	342	Shared Neighborhood Hits	49
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

JARD2_MOUSE
θ value	1.80466e-16 (rank : 28)	NC score	0.548000 (rank : 28)
Query Neighborhood Hits	152	Target Neighborhood Hits	169	Shared Neighborhood Hits	25
SwissProt Accessions	Q62315, Q99LD1	Gene names	Jarid2, Jmj
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

JARD2_HUMAN
θ value	2.60593e-15 (rank : 29)	NC score	0.543935 (rank : 29)
Query Neighborhood Hits	152	Target Neighborhood Hits	119	Shared Neighborhood Hits	23
SwissProt Accessions	Q92833, Q5U5L5	Gene names	JARID2, JMJ
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

NFH_MOUSE
θ value	5.81887e-07 (rank : 30)	NC score	0.049232 (rank : 121)
Query Neighborhood Hits	152	Target Neighborhood Hits	2247	Shared Neighborhood Hits	88
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

TXND2_HUMAN
θ value	0.000461057 (rank : 31)	NC score	0.061089 (rank : 106)
Query Neighborhood Hits	152	Target Neighborhood Hits	793	Shared Neighborhood Hits	51
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

MLL4_HUMAN
θ value	0.00134147 (rank : 32)	NC score	0.199835 (rank : 31)
Query Neighborhood Hits	152	Target Neighborhood Hits	722	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

MLL3_MOUSE
θ value	0.00175202 (rank : 33)	NC score	0.189551 (rank : 32)
Query Neighborhood Hits	152	Target Neighborhood Hits	1399	Shared Neighborhood Hits	89
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MLL3_HUMAN
θ value	0.00298849 (rank : 34)	NC score	0.176144 (rank : 36)
Query Neighborhood Hits	152	Target Neighborhood Hits	1644	Shared Neighborhood Hits	95
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

HRX_HUMAN
θ value	0.00509761 (rank : 35)	NC score	0.176779 (rank : 35)
Query Neighborhood Hits	152	Target Neighborhood Hits	825	Shared Neighborhood Hits	82
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

OGFR_HUMAN
θ value	0.00869519 (rank : 36)	NC score	0.050936 (rank : 120)
Query Neighborhood Hits	152	Target Neighborhood Hits	1582	Shared Neighborhood Hits	66
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

LIMD1_MOUSE
θ value	0.0148317 (rank : 37)	NC score	0.021544 (rank : 159)
Query Neighborhood Hits	152	Target Neighborhood Hits	291	Shared Neighborhood Hits	15
SwissProt Accessions	Q9QXD8, Q8C8G4, Q9CW55	Gene names	Limd1
Domain Architecture
Description	LIM domain-containing protein 1.

PHF11_HUMAN
θ value	0.0193708 (rank : 38)	NC score	0.208457 (rank : 30)
Query Neighborhood Hits	152	Target Neighborhood Hits	42	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UIL8, Q9Y5A2	Gene names	PHF11, BCAP
Domain Architecture	No domain graphic available
Description	PHD finger protein 11 (BRCA1 C-terminus-associated protein) (NY-REN-34 antigen).

RAI1_MOUSE
θ value	0.0736092 (rank : 39)	NC score	0.147892 (rank : 43)
Query Neighborhood Hits	152	Target Neighborhood Hits	344	Shared Neighborhood Hits	58
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

AFF4_MOUSE
θ value	0.163984 (rank : 40)	NC score	0.039865 (rank : 128)
Query Neighborhood Hits	152	Target Neighborhood Hits	581	Shared Neighborhood Hits	38
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

MDC1_MOUSE
θ value	0.163984 (rank : 41)	NC score	0.053710 (rank : 115)
Query Neighborhood Hits	152	Target Neighborhood Hits	998	Shared Neighborhood Hits	67
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

RGS3_MOUSE
θ value	0.163984 (rank : 42)	NC score	0.030133 (rank : 138)
Query Neighborhood Hits	152	Target Neighborhood Hits	1621	Shared Neighborhood Hits	63
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SON_HUMAN
θ value	0.163984 (rank : 43)	NC score	0.041817 (rank : 126)
Query Neighborhood Hits	152	Target Neighborhood Hits	1568	Shared Neighborhood Hits	63
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

LBR_HUMAN
θ value	0.21417 (rank : 44)	NC score	0.094599 (rank : 78)
Query Neighborhood Hits	152	Target Neighborhood Hits	25	Shared Neighborhood Hits	8
SwissProt Accessions	Q14739, Q14740, Q53GU7, Q59FE6	Gene names	LBR
Domain Architecture
Description	Lamin-B receptor (Integral nuclear envelope inner membrane protein) (LMN2R).

PTN22_MOUSE
θ value	0.279714 (rank : 45)	NC score	0.011934 (rank : 184)
Query Neighborhood Hits	152	Target Neighborhood Hits	179	Shared Neighborhood Hits	11
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

AMPH_HUMAN
θ value	0.365318 (rank : 46)	NC score	0.028878 (rank : 140)
Query Neighborhood Hits	152	Target Neighborhood Hits	455	Shared Neighborhood Hits	31
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

ARMX2_MOUSE
θ value	0.365318 (rank : 47)	NC score	0.031754 (rank : 135)
Query Neighborhood Hits	152	Target Neighborhood Hits	349	Shared Neighborhood Hits	27
SwissProt Accessions	Q6A058, Q9CXI9	Gene names	Armcx2, Kiaa0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2.

FA21C_HUMAN
θ value	0.365318 (rank : 48)	NC score	0.035006 (rank : 132)
Query Neighborhood Hits	152	Target Neighborhood Hits	194	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y4E1, Q5SQU4, Q5SQU5, Q7L521, Q9UG79	Gene names	FAM21C, KIAA0592
Domain Architecture	No domain graphic available
Description	Protein FAM21C.

HSF1_MOUSE
θ value	0.365318 (rank : 49)	NC score	0.028790 (rank : 141)
Query Neighborhood Hits	152	Target Neighborhood Hits	267	Shared Neighborhood Hits	21
SwissProt Accessions	P38532, O70462	Gene names	Hsf1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

SPEG_MOUSE
θ value	0.365318 (rank : 50)	NC score	0.010318 (rank : 190)
Query Neighborhood Hits	152	Target Neighborhood Hits	1959	Shared Neighborhood Hits	67
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

PHF7_MOUSE
θ value	0.47712 (rank : 51)	NC score	0.189309 (rank : 33)
Query Neighborhood Hits	152	Target Neighborhood Hits	65	Shared Neighborhood Hits	39
SwissProt Accessions	Q9DAG9, Q6PG81	Gene names	Phf7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

TCF20_HUMAN
θ value	0.47712 (rank : 52)	NC score	0.106963 (rank : 66)
Query Neighborhood Hits	152	Target Neighborhood Hits	323	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

TCF20_MOUSE
θ value	0.47712 (rank : 53)	NC score	0.102247 (rank : 71)
Query Neighborhood Hits	152	Target Neighborhood Hits	396	Shared Neighborhood Hits	50
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

CEL_HUMAN
θ value	0.62314 (rank : 54)	NC score	0.015614 (rank : 170)
Query Neighborhood Hits	152	Target Neighborhood Hits	896	Shared Neighborhood Hits	35
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

CU121_HUMAN
θ value	0.62314 (rank : 55)	NC score	0.043103 (rank : 125)
Query Neighborhood Hits	152	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N0V1	Gene names	C21orf121
Domain Architecture	No domain graphic available
Description	Protein C21orf121.

E41L3_MOUSE
θ value	0.62314 (rank : 56)	NC score	0.013452 (rank : 180)
Query Neighborhood Hits	152	Target Neighborhood Hits	250	Shared Neighborhood Hits	11
SwissProt Accessions	Q9WV92, Q9R102	Gene names	Epb41l3, Dal1, Epb4.1l3
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1).

LBR_MOUSE
θ value	0.62314 (rank : 57)	NC score	0.090539 (rank : 82)
Query Neighborhood Hits	152	Target Neighborhood Hits	23	Shared Neighborhood Hits	8
SwissProt Accessions	Q3U9G9, Q3TSW2, Q811V8, Q811V9, Q8BST3, Q8K2Y8, Q8VDM0, Q91YS5, Q91Z27	Gene names	Lbr
Domain Architecture	No domain graphic available
Description	Lamin-B receptor (Integral nuclear envelope inner membrane protein).

NACAM_MOUSE
θ value	0.62314 (rank : 58)	NC score	0.054075 (rank : 114)
Query Neighborhood Hits	152	Target Neighborhood Hits	1866	Shared Neighborhood Hits	85
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

RAI1_HUMAN
θ value	0.62314 (rank : 59)	NC score	0.137556 (rank : 46)
Query Neighborhood Hits	152	Target Neighborhood Hits	360	Shared Neighborhood Hits	50
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

SC24C_HUMAN
θ value	0.62314 (rank : 60)	NC score	0.026811 (rank : 149)
Query Neighborhood Hits	152	Target Neighborhood Hits	662	Shared Neighborhood Hits	37
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

ARI4A_HUMAN
θ value	0.813845 (rank : 61)	NC score	0.097491 (rank : 75)
Query Neighborhood Hits	152	Target Neighborhood Hits	434	Shared Neighborhood Hits	20
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

ASXL1_HUMAN
θ value	0.813845 (rank : 62)	NC score	0.025446 (rank : 152)
Query Neighborhood Hits	152	Target Neighborhood Hits	260	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IXJ9, Q5JWS9, Q8IYY7, Q9H466, Q9NQF8, Q9UFJ0, Q9UFP8, Q9Y2I4	Gene names	ASXL1, KIAA0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

CJ012_HUMAN
θ value	0.813845 (rank : 63)	NC score	0.053685 (rank : 116)
Query Neighborhood Hits	152	Target Neighborhood Hits	467	Shared Neighborhood Hits	41
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

WDR24_HUMAN
θ value	0.813845 (rank : 64)	NC score	0.027532 (rank : 145)
Query Neighborhood Hits	152	Target Neighborhood Hits	247	Shared Neighborhood Hits	5
SwissProt Accessions	Q96S15, Q96GC7, Q9H0B7	Gene names	WDR24
Domain Architecture	No domain graphic available
Description	WD repeat protein 24.

WDR24_MOUSE
θ value	0.813845 (rank : 65)	NC score	0.021673 (rank : 158)
Query Neighborhood Hits	152	Target Neighborhood Hits	286	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CFJ9	Gene names	Wdr24
Domain Architecture	No domain graphic available
Description	WD repeat protein 24.

PHF7_HUMAN
θ value	1.06291 (rank : 66)	NC score	0.149262 (rank : 42)
Query Neighborhood Hits	152	Target Neighborhood Hits	71	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BWX1	Gene names	PHF7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

PO6F1_MOUSE
θ value	1.06291 (rank : 67)	NC score	0.009657 (rank : 194)
Query Neighborhood Hits	152	Target Neighborhood Hits	581	Shared Neighborhood Hits	18
SwissProt Accessions	Q07916, Q91XK3	Gene names	Pou6f1, Emb
Domain Architecture
Description	POU domain, class 6, transcription factor 1 (Octamer-binding transcription factor EMB) (Transcription regulatory protein MCP-1).

SSBP4_HUMAN
θ value	1.06291 (rank : 68)	NC score	0.015255 (rank : 172)
Query Neighborhood Hits	152	Target Neighborhood Hits	753	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

AL2S8_MOUSE
θ value	1.38821 (rank : 69)	NC score	0.018936 (rank : 163)
Query Neighborhood Hits	152	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VHI4	Gene names	Als2cr8, Carf
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein homolog (Calcium-response factor) (CaRF).

APXL_HUMAN
θ value	1.38821 (rank : 70)	NC score	0.027399 (rank : 147)
Query Neighborhood Hits	152	Target Neighborhood Hits	553	Shared Neighborhood Hits	30
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

BRE1B_HUMAN
θ value	1.38821 (rank : 71)	NC score	0.009430 (rank : 196)
Query Neighborhood Hits	152	Target Neighborhood Hits	1040	Shared Neighborhood Hits	18
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

MAST4_HUMAN
θ value	1.38821 (rank : 72)	NC score	0.006089 (rank : 203)
Query Neighborhood Hits	152	Target Neighborhood Hits	1804	Shared Neighborhood Hits	63
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

MYST4_HUMAN
θ value	1.38821 (rank : 73)	NC score	0.107488 (rank : 64)
Query Neighborhood Hits	152	Target Neighborhood Hits	671	Shared Neighborhood Hits	55
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

MYST4_MOUSE
θ value	1.38821 (rank : 74)	NC score	0.107369 (rank : 65)
Query Neighborhood Hits	152	Target Neighborhood Hits	416	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

NIPBL_HUMAN
θ value	1.38821 (rank : 75)	NC score	0.040528 (rank : 127)
Query Neighborhood Hits	152	Target Neighborhood Hits	1311	Shared Neighborhood Hits	58
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

PSL1_HUMAN
θ value	1.38821 (rank : 76)	NC score	0.023186 (rank : 154)
Query Neighborhood Hits	152	Target Neighborhood Hits	650	Shared Neighborhood Hits	33
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

RBBP6_MOUSE
θ value	1.38821 (rank : 77)	NC score	0.027338 (rank : 148)
Query Neighborhood Hits	152	Target Neighborhood Hits	1014	Shared Neighborhood Hits	41
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

ANC1_MOUSE
θ value	1.81305 (rank : 78)	NC score	0.014604 (rank : 176)
Query Neighborhood Hits	152	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	P53995, Q8BP33, Q8C772	Gene names	Anapc1, Mcpr, Tsg24
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Protein Tsg24) (Mitotic checkpoint regulator).

BC11B_MOUSE
θ value	1.81305 (rank : 79)	NC score	-0.000432 (rank : 210)
Query Neighborhood Hits	152	Target Neighborhood Hits	767	Shared Neighborhood Hits	13
SwissProt Accessions	Q99PV8, Q8C2I1, Q99PV6, Q99PV7, Q9JLF8	Gene names	Bcl11b, Ctip2, Rit1
Domain Architecture	No domain graphic available
Description	B-cell lymphoma/leukemia 11B (B-cell CLL/lymphoma 11B) (Radiation- induced tumor suppressor gene 1 protein) (mRit1) (COUP-TF-interacting protein 2).

BCOR_HUMAN
θ value	1.81305 (rank : 80)	NC score	0.009923 (rank : 192)
Query Neighborhood Hits	152	Target Neighborhood Hits	609	Shared Neighborhood Hits	25
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

DPCA2_HUMAN
θ value	1.81305 (rank : 81)	NC score	0.030703 (rank : 137)
Query Neighborhood Hits	152	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q86SG4, Q86SH8, Q8N8I5	Gene names	C15orf21
Domain Architecture	No domain graphic available
Description	Dresden prostate carcinoma 2 protein (D-PCa-2).

K1802_HUMAN
θ value	1.81305 (rank : 82)	NC score	0.028424 (rank : 143)
Query Neighborhood Hits	152	Target Neighborhood Hits	1378	Shared Neighborhood Hits	63
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MICA1_HUMAN
θ value	1.81305 (rank : 83)	NC score	0.010751 (rank : 187)
Query Neighborhood Hits	152	Target Neighborhood Hits	279	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TDZ2, Q7Z633, Q8IVS9, Q96G47, Q9H6X6, Q9H7I0, Q9HAA1, Q9UFF7	Gene names	MICAL1, MICAL, NICAL
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

PHF1_HUMAN
θ value	1.81305 (rank : 84)	NC score	0.154352 (rank : 40)
Query Neighborhood Hits	152	Target Neighborhood Hits	117	Shared Neighborhood Hits	32
SwissProt Accessions	O43189, O60929, Q96KM7	Gene names	PHF1
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1).

PHF1_MOUSE
θ value	1.81305 (rank : 85)	NC score	0.155028 (rank : 39)
Query Neighborhood Hits	152	Target Neighborhood Hits	116	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Z1B8, O54808	Gene names	Phf1, Tctex-3, Tctex3
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1) (T-complex testis-expressed 3) (Polycomblike 1) (mPCl1).

RRBP1_HUMAN
θ value	1.81305 (rank : 86)	NC score	0.017420 (rank : 166)
Query Neighborhood Hits	152	Target Neighborhood Hits	1306	Shared Neighborhood Hits	35
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

CAC1G_HUMAN
θ value	2.36792 (rank : 87)	NC score	0.011799 (rank : 185)
Query Neighborhood Hits	152	Target Neighborhood Hits	587	Shared Neighborhood Hits	29
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

DOK2_MOUSE
θ value	2.36792 (rank : 88)	NC score	0.014677 (rank : 174)
Query Neighborhood Hits	152	Target Neighborhood Hits	244	Shared Neighborhood Hits	16
SwissProt Accessions	O70469, O70272, Q99KL1	Gene names	Dok2, Frip
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)) (Dok- related protein) (Dok-R) (IL-four receptor-interacting protein) (FRIP).

EVI1_HUMAN
θ value	2.36792 (rank : 89)	NC score	-0.002178 (rank : 212)
Query Neighborhood Hits	152	Target Neighborhood Hits	924	Shared Neighborhood Hits	16
SwissProt Accessions	Q03112, Q16122, Q99917	Gene names	EVI1
Domain Architecture
Description	Ecotropic virus integration 1 site protein.

EVL_HUMAN
θ value	2.36792 (rank : 90)	NC score	0.021407 (rank : 160)
Query Neighborhood Hits	152	Target Neighborhood Hits	260	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UI08, O95884, Q7Z522, Q8TBV1, Q9UF25, Q9UIC2	Gene names	EVL, RNB6
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

K1333_MOUSE
θ value	2.36792 (rank : 91)	NC score	0.100042 (rank : 74)
Query Neighborhood Hits	152	Target Neighborhood Hits	53	Shared Neighborhood Hits	28
SwissProt Accessions	Q5RJY2, Q6ZPT7, Q8BNA4	Gene names	Kiaa1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

K1802_MOUSE
θ value	2.36792 (rank : 92)	NC score	0.027813 (rank : 144)
Query Neighborhood Hits	152	Target Neighborhood Hits	1596	Shared Neighborhood Hits	68
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

NCOR2_MOUSE
θ value	2.36792 (rank : 93)	NC score	0.028623 (rank : 142)
Query Neighborhood Hits	152	Target Neighborhood Hits	790	Shared Neighborhood Hits	48
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

PRRT3_HUMAN
θ value	2.36792 (rank : 94)	NC score	0.035366 (rank : 131)
Query Neighborhood Hits	152	Target Neighborhood Hits	998	Shared Neighborhood Hits	50
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

WHRN_MOUSE
θ value	2.36792 (rank : 95)	NC score	0.016276 (rank : 169)
Query Neighborhood Hits	152	Target Neighborhood Hits	412	Shared Neighborhood Hits	26
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

ZN509_MOUSE
θ value	2.36792 (rank : 96)	NC score	-0.000932 (rank : 211)
Query Neighborhood Hits	152	Target Neighborhood Hits	990	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BXX2, Q8CID4, Q8K2Z6	Gene names	Znf509, Zfp509
Domain Architecture	No domain graphic available
Description	Zinc finger protein 509.

CP053_MOUSE
θ value	3.0926 (rank : 97)	NC score	0.017975 (rank : 164)
Query Neighborhood Hits	152	Target Neighborhood Hits	38	Shared Neighborhood Hits	6
SwissProt Accessions	Q99L02	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf53 homolog.

EPN3_HUMAN
θ value	3.0926 (rank : 98)	NC score	0.014691 (rank : 173)
Query Neighborhood Hits	152	Target Neighborhood Hits	197	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H201, Q9BVN6, Q9NWK2	Gene names	EPN3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

ETV3_HUMAN
θ value	3.0926 (rank : 99)	NC score	0.017170 (rank : 167)
Query Neighborhood Hits	152	Target Neighborhood Hits	312	Shared Neighborhood Hits	29
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

MINT_MOUSE
θ value	3.0926 (rank : 100)	NC score	0.031698 (rank : 136)
Query Neighborhood Hits	152	Target Neighborhood Hits	1514	Shared Neighborhood Hits	70
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MLL2_HUMAN
θ value	3.0926 (rank : 101)	NC score	0.176959 (rank : 34)
Query Neighborhood Hits	152	Target Neighborhood Hits	1788	Shared Neighborhood Hits	106
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

NFM_HUMAN
θ value	3.0926 (rank : 102)	NC score	0.012282 (rank : 182)
Query Neighborhood Hits	152	Target Neighborhood Hits	1328	Shared Neighborhood Hits	49
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

NPHN_MOUSE
θ value	3.0926 (rank : 103)	NC score	0.008307 (rank : 198)
Query Neighborhood Hits	152	Target Neighborhood Hits	370	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QZS7	Gene names	Nphs1, Nphn
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

RRBP1_MOUSE
θ value	3.0926 (rank : 104)	NC score	0.014621 (rank : 175)
Query Neighborhood Hits	152	Target Neighborhood Hits	1650	Shared Neighborhood Hits	41
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

SPEG_HUMAN
θ value	3.0926 (rank : 105)	NC score	0.007654 (rank : 201)
Query Neighborhood Hits	152	Target Neighborhood Hits	1762	Shared Neighborhood Hits	61
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

ZN750_MOUSE
θ value	3.0926 (rank : 106)	NC score	0.028925 (rank : 139)
Query Neighborhood Hits	152	Target Neighborhood Hits	346	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

ASPP1_MOUSE
θ value	4.03905 (rank : 107)	NC score	0.017874 (rank : 165)
Query Neighborhood Hits	152	Target Neighborhood Hits	1244	Shared Neighborhood Hits	53
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

GNAS1_HUMAN
θ value	4.03905 (rank : 108)	NC score	0.014311 (rank : 178)
Query Neighborhood Hits	152	Target Neighborhood Hits	278	Shared Neighborhood Hits	29
SwissProt Accessions	Q5JWF2, O75684, O75685, Q5JW67, Q5JWF1, Q9NY42	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

GRIN1_HUMAN
θ value	4.03905 (rank : 109)	NC score	0.021860 (rank : 157)
Query Neighborhood Hits	152	Target Neighborhood Hits	681	Shared Neighborhood Hits	39
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

NEK4_MOUSE
θ value	4.03905 (rank : 110)	NC score	-0.002843 (rank : 214)
Query Neighborhood Hits	152	Target Neighborhood Hits	899	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z1J2, O35673, Q9R1J1	Gene names	Nek4, Stk2
Domain Architecture
Description	Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2).

NPHN_HUMAN
θ value	4.03905 (rank : 111)	NC score	0.007860 (rank : 200)
Query Neighborhood Hits	152	Target Neighborhood Hits	362	Shared Neighborhood Hits	8
SwissProt Accessions	O60500	Gene names	NPHS1, NPHN
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

PHF13_HUMAN
θ value	4.03905 (rank : 112)	NC score	0.045263 (rank : 123)
Query Neighborhood Hits	152	Target Neighborhood Hits	41	Shared Neighborhood Hits	10
SwissProt Accessions	Q86YI8, Q8N551, Q9UJP2	Gene names	PHF13
Domain Architecture
Description	PHD finger protein 13.

PHF13_MOUSE
θ value	4.03905 (rank : 113)	NC score	0.045321 (rank : 122)
Query Neighborhood Hits	152	Target Neighborhood Hits	42	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K2W6	Gene names	Phf13
Domain Architecture
Description	PHD finger protein 13.

TCEA2_HUMAN
θ value	4.03905 (rank : 114)	NC score	0.009880 (rank : 193)
Query Neighborhood Hits	152	Target Neighborhood Hits	81	Shared Neighborhood Hits	5
SwissProt Accessions	Q15560, Q8TD37, Q8TD38	Gene names	TCEA2
Domain Architecture
Description	Transcription elongation factor A protein 2 (Transcription elongation factor S-II protein 2) (Testis-specific S-II) (Transcription elongation factor TFIIS.l).

ZN645_HUMAN
θ value	4.03905 (rank : 115)	NC score	0.019349 (rank : 162)
Query Neighborhood Hits	152	Target Neighborhood Hits	265	Shared Neighborhood Hits	14
SwissProt Accessions	Q8N7E2, Q6DJY9	Gene names	ZNF645
Domain Architecture	No domain graphic available
Description	Zinc finger protein 645.

ATN1_HUMAN
θ value	5.27518 (rank : 116)	NC score	0.039369 (rank : 129)
Query Neighborhood Hits	152	Target Neighborhood Hits	676	Shared Neighborhood Hits	47
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

BRCA2_MOUSE
θ value	5.27518 (rank : 117)	NC score	0.011797 (rank : 186)
Query Neighborhood Hits	152	Target Neighborhood Hits	222	Shared Neighborhood Hits	14
SwissProt Accessions	P97929, O35922, P97383	Gene names	Brca2, Fancd1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein homolog (Fanconi anemia group D1 protein homolog).

K1333_HUMAN
θ value	5.27518 (rank : 118)	NC score	0.074643 (rank : 95)
Query Neighborhood Hits	152	Target Neighborhood Hits	50	Shared Neighborhood Hits	28
SwissProt Accessions	Q7L622, Q9BVR2, Q9H9E9, Q9NXC0, Q9P2L3	Gene names	KIAA1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

K1683_HUMAN
θ value	5.27518 (rank : 119)	NC score	0.019542 (rank : 161)
Query Neighborhood Hits	152	Target Neighborhood Hits	240	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

MAGE1_HUMAN
θ value	5.27518 (rank : 120)	NC score	0.022640 (rank : 156)
Query Neighborhood Hits	152	Target Neighborhood Hits	1389	Shared Neighborhood Hits	64
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MEGF9_MOUSE
θ value	5.27518 (rank : 121)	NC score	0.008190 (rank : 199)
Query Neighborhood Hits	152	Target Neighborhood Hits	896	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MELK_MOUSE
θ value	5.27518 (rank : 122)	NC score	-0.002810 (rank : 213)
Query Neighborhood Hits	152	Target Neighborhood Hits	860	Shared Neighborhood Hits	7
SwissProt Accessions	Q61846, Q61804, Q6ZQH6	Gene names	Melk, Kiaa0175, Pk38
Domain Architecture	No domain graphic available
Description	Maternal embryonic leucine zipper kinase (EC 2.7.11.1) (Protein kinase PK38) (mPK38).

MILK1_MOUSE
θ value	5.27518 (rank : 123)	NC score	0.033084 (rank : 134)
Query Neighborhood Hits	152	Target Neighborhood Hits	788	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

SRBP1_MOUSE
θ value	5.27518 (rank : 124)	NC score	0.016748 (rank : 168)
Query Neighborhood Hits	152	Target Neighborhood Hits	384	Shared Neighborhood Hits	24
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

TAU_MOUSE
θ value	5.27518 (rank : 125)	NC score	0.027468 (rank : 146)
Query Neighborhood Hits	152	Target Neighborhood Hits	502	Shared Neighborhood Hits	39
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TITIN_HUMAN
θ value	5.27518 (rank : 126)	NC score	0.010425 (rank : 189)
Query Neighborhood Hits	152	Target Neighborhood Hits	2923	Shared Neighborhood Hits	72
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

AL1A3_HUMAN
θ value	6.88961 (rank : 127)	NC score	0.002373 (rank : 208)
Query Neighborhood Hits	152	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	P47895, Q6NT64	Gene names	ALDH1A3, ALDH6
Domain Architecture
Description	Aldehyde dehydrogenase 1A3 (EC 1.2.1.5) (Aldehyde dehydrogenase 6) (Retinaldehyde dehydrogenase 3) (RALDH-3).

ALO17_HUMAN
θ value	6.88961 (rank : 128)	NC score	0.025177 (rank : 153)
Query Neighborhood Hits	152	Target Neighborhood Hits	317	Shared Neighborhood Hits	24
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

CLSPN_MOUSE
θ value	6.88961 (rank : 129)	NC score	0.010429 (rank : 188)
Query Neighborhood Hits	152	Target Neighborhood Hits	292	Shared Neighborhood Hits	9
SwissProt Accessions	Q80YR7, Q69GM2	Gene names	Clspn
Domain Architecture	No domain graphic available
Description	Claspin.

DSCAM_HUMAN
θ value	6.88961 (rank : 130)	NC score	0.002284 (rank : 209)
Query Neighborhood Hits	152	Target Neighborhood Hits	524	Shared Neighborhood Hits	9
SwissProt Accessions	O60469, O60468	Gene names	DSCAM
Domain Architecture
Description	Down syndrome cell adhesion molecule precursor (CHD2).

GA2L2_MOUSE
θ value	6.88961 (rank : 131)	NC score	0.012837 (rank : 181)
Query Neighborhood Hits	152	Target Neighborhood Hits	395	Shared Neighborhood Hits	25
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

PI5PA_MOUSE
θ value	6.88961 (rank : 132)	NC score	0.022952 (rank : 155)
Query Neighborhood Hits	152	Target Neighborhood Hits	331	Shared Neighborhood Hits	39
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

RGS3_HUMAN
θ value	6.88961 (rank : 133)	NC score	0.025585 (rank : 150)
Query Neighborhood Hits	152	Target Neighborhood Hits	1375	Shared Neighborhood Hits	55
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

RHG05_HUMAN
θ value	6.88961 (rank : 134)	NC score	0.003023 (rank : 207)
Query Neighborhood Hits	152	Target Neighborhood Hits	158	Shared Neighborhood Hits	2
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

S3TC1_HUMAN
θ value	6.88961 (rank : 135)	NC score	0.009145 (rank : 197)
Query Neighborhood Hits	152	Target Neighborhood Hits	78	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TE82	Gene names	SH3TC1
Domain Architecture	No domain graphic available
Description	SH3 domain and tetratricopeptide repeats-containing protein 1.

SDPR_HUMAN
θ value	6.88961 (rank : 136)	NC score	0.014343 (rank : 177)
Query Neighborhood Hits	152	Target Neighborhood Hits	337	Shared Neighborhood Hits	12
SwissProt Accessions	O95810	Gene names	SDPR
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein) (PS-p68).

SRCA_HUMAN
θ value	6.88961 (rank : 137)	NC score	0.025554 (rank : 151)
Query Neighborhood Hits	152	Target Neighborhood Hits	380	Shared Neighborhood Hits	34
SwissProt Accessions	Q86TD4	Gene names	SRL
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

TARSH_HUMAN
θ value	6.88961 (rank : 138)	NC score	0.034343 (rank : 133)
Query Neighborhood Hits	152	Target Neighborhood Hits	768	Shared Neighborhood Hits	51
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

VP13A_HUMAN
θ value	6.88961 (rank : 139)	NC score	0.010079 (rank : 191)
Query Neighborhood Hits	152	Target Neighborhood Hits	93	Shared Neighborhood Hits	4
SwissProt Accessions	Q96RL7, Q5JSX9, Q5JSY0, Q5VYR5, Q702P4, Q709D0, Q86YF8, Q96S61, Q9H995, Q9Y2J1	Gene names	VPS13A, CHAC, KIAA0986
Domain Architecture
Description	Vacuolar protein sorting-associated protein 13A (Chorein) (Chorea- acanthocytosis protein).

B4GN4_MOUSE
θ value	8.99809 (rank : 140)	NC score	0.005017 (rank : 205)
Query Neighborhood Hits	152	Target Neighborhood Hits	129	Shared Neighborhood Hits	8
SwissProt Accessions	Q766D5, Q8CHV2	Gene names	B4galnt4
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 1 (EC 2.4.1.244) (NGalNAc-T1) (Beta- 1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4).

BRE1B_MOUSE
θ value	8.99809 (rank : 141)	NC score	0.006795 (rank : 202)
Query Neighborhood Hits	152	Target Neighborhood Hits	970	Shared Neighborhood Hits	15
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

CHD3_HUMAN
θ value	8.99809 (rank : 142)	NC score	0.086701 (rank : 85)
Query Neighborhood Hits	152	Target Neighborhood Hits	397	Shared Neighborhood Hits	52
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

CSKI1_HUMAN
θ value	8.99809 (rank : 143)	NC score	0.015355 (rank : 171)
Query Neighborhood Hits	152	Target Neighborhood Hits	997	Shared Neighborhood Hits	55
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

LPP_HUMAN
θ value	8.99809 (rank : 144)	NC score	0.012147 (rank : 183)
Query Neighborhood Hits	152	Target Neighborhood Hits	775	Shared Neighborhood Hits	37
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

MDC1_HUMAN
θ value	8.99809 (rank : 145)	NC score	0.037300 (rank : 130)
Query Neighborhood Hits	152	Target Neighborhood Hits	1446	Shared Neighborhood Hits	62
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MYST3_HUMAN
θ value	8.99809 (rank : 146)	NC score	0.110419 (rank : 60)
Query Neighborhood Hits	152	Target Neighborhood Hits	772	Shared Neighborhood Hits	68
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

NCOA7_MOUSE
θ value	8.99809 (rank : 147)	NC score	0.009433 (rank : 195)
Query Neighborhood Hits	152	Target Neighborhood Hits	114	Shared Neighborhood Hits	7
SwissProt Accessions	Q6DFV7, Q3TAR1, Q3UNB3, Q66K05, Q6ZQM4, Q8BJ15, Q8BJ39	Gene names	Ncoa7
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 7.

RPGF1_HUMAN
θ value	8.99809 (rank : 148)	NC score	0.005981 (rank : 204)
Query Neighborhood Hits	152	Target Neighborhood Hits	262	Shared Neighborhood Hits	14
SwissProt Accessions	Q13905	Gene names	RAPGEF1, GRF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP).

SC5A4_HUMAN
θ value	8.99809 (rank : 149)	NC score	0.003122 (rank : 206)
Query Neighborhood Hits	152	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NY91, O15279	Gene names	SLC5A4, SAAT1, SGLT2
Domain Architecture
Description	Low affinity sodium-glucose cotransporter (Sodium/glucose cotransporter 3) (Na(+)/glucose cotransporter 3).

SYNPO_HUMAN
θ value	8.99809 (rank : 150)	NC score	0.013980 (rank : 179)
Query Neighborhood Hits	152	Target Neighborhood Hits	281	Shared Neighborhood Hits	24
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

TCOF_HUMAN
θ value	8.99809 (rank : 151)	NC score	0.043402 (rank : 124)
Query Neighborhood Hits	152	Target Neighborhood Hits	543	Shared Neighborhood Hits	45
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

ZN398_HUMAN
θ value	8.99809 (rank : 152)	NC score	-0.004037 (rank : 215)
Query Neighborhood Hits	152	Target Neighborhood Hits	765	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TD17, Q8TD18, Q9P2K7, Q9UDV8	Gene names	ZNF398, KIAA1339, ZER6
Domain Architecture
Description	Zinc finger protein 398 (Zinc finger DNA-binding protein p52/p71).

AIRE_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.153383 (rank : 41)
Query Neighborhood Hits	152	Target Neighborhood Hits	144	Shared Neighborhood Hits	34
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

AIRE_MOUSE
θ value	θ > 10 (rank : 154)	NC score	0.144106 (rank : 44)
Query Neighborhood Hits	152	Target Neighborhood Hits	196	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

ARI1A_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.068585 (rank : 100)
Query Neighborhood Hits	152	Target Neighborhood Hits	787	Shared Neighborhood Hits	50
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

ARI1B_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.076110 (rank : 94)
Query Neighborhood Hits	152	Target Neighborhood Hits	567	Shared Neighborhood Hits	47
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

ARI3A_HUMAN
θ value	θ > 10 (rank : 157)	NC score	0.108384 (rank : 62)
Query Neighborhood Hits	152	Target Neighborhood Hits	80	Shared Neighborhood Hits	16
SwissProt Accessions	Q99856, Q8IZA7	Gene names	ARID3A, DRIL1, DRX, E2FBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 3A (ARID domain- containing protein 3A) (B-cell regulator of IgH transcription) (Bright) (E2F-binding protein 1).

ARI3A_MOUSE
θ value	θ > 10 (rank : 158)	NC score	0.108180 (rank : 63)
Query Neighborhood Hits	152	Target Neighborhood Hits	64	Shared Neighborhood Hits	9
SwissProt Accessions	Q62431	Gene names	Arid3a, Dri1, Dril1
Domain Architecture
Description	AT-rich interactive domain-containing protein 3A (ARID domain- containing protein 3A) (Dead ringer-like protein 1) (B-cell regulator of IgH transcription) (Bright).

ARI5B_HUMAN
θ value	θ > 10 (rank : 159)	NC score	0.069616 (rank : 98)
Query Neighborhood Hits	152	Target Neighborhood Hits	328	Shared Neighborhood Hits	31
SwissProt Accessions	Q14865, Q7Z3M4, Q8N421, Q9H786	Gene names	ARID5B, DESRT, MRF2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (Mrf1-like) (Modulator recognition factor 2) (MRF-2).

ARI5B_MOUSE
θ value	θ > 10 (rank : 160)	NC score	0.068729 (rank : 99)
Query Neighborhood Hits	152	Target Neighborhood Hits	158	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BM75, Q8C0E0, Q8K4G8, Q8K4L9, Q9CU78, Q9JIX4	Gene names	Arid5b, Desrt, Mrf2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (MRF1-like) (Modulator recognition factor protein 2) (MRF-2) (Developmentally and sexually retarded with transient immune abnormalities protein).

ARID2_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.086227 (rank : 87)
Query Neighborhood Hits	152	Target Neighborhood Hits	302	Shared Neighborhood Hits	27
SwissProt Accessions	Q68CP9, Q5EB51, Q645I3, Q6ZRY5, Q7Z3I5, Q86T28, Q96SJ6, Q9HCL5	Gene names	ARID2, KIAA1557
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 2 (ARID domain- containing protein 2) (BRG1-associated factor 200) (BAF200).

BASP_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.054353 (rank : 112)
Query Neighborhood Hits	152	Target Neighborhood Hits	321	Shared Neighborhood Hits	43
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BAZ1A_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.123031 (rank : 50)
Query Neighborhood Hits	152	Target Neighborhood Hits	693	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

BAZ1B_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.122585 (rank : 51)
Query Neighborhood Hits	152	Target Neighborhood Hits	701	Shared Neighborhood Hits	48
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

BAZ1B_MOUSE
θ value	θ > 10 (rank : 165)	NC score	0.130647 (rank : 49)
Query Neighborhood Hits	152	Target Neighborhood Hits	394	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

BAZ2A_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.112326 (rank : 56)
Query Neighborhood Hits	152	Target Neighborhood Hits	780	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

BAZ2A_MOUSE
θ value	θ > 10 (rank : 167)	NC score	0.110606 (rank : 59)
Query Neighborhood Hits	152	Target Neighborhood Hits	744	Shared Neighborhood Hits	61
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

BAZ2B_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.103676 (rank : 68)
Query Neighborhood Hits	152	Target Neighborhood Hits	803	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

BPTF_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.103059 (rank : 69)
Query Neighborhood Hits	152	Target Neighborhood Hits	786	Shared Neighborhood Hits	63
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

BRD7_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.055498 (rank : 110)
Query Neighborhood Hits	152	Target Neighborhood Hits	94	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NPI1, Q4VC09, Q8N2L9, Q96KA4, Q9BV48, Q9UH59	Gene names	BRD7, BP75, CELTIX1
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein) (Protein CELTIX-1).

BRD7_MOUSE
θ value	θ > 10 (rank : 171)	NC score	0.054528 (rank : 111)
Query Neighborhood Hits	152	Target Neighborhood Hits	141	Shared Neighborhood Hits	8
SwissProt Accessions	O88665, Q3UQ56, Q3UU06, Q9CT78	Gene names	Brd7, Bp75
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein).

BRD9_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.056478 (rank : 108)
Query Neighborhood Hits	152	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H8M2, Q2XUS1, Q6UWU9, Q8IUS4, Q9H5Q5, Q9H7R9	Gene names	BRD9
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 9 (Rhabdomyosarcoma antigen MU-RMS- 40.8).

BRD9_MOUSE
θ value	θ > 10 (rank : 173)	NC score	0.054153 (rank : 113)
Query Neighborhood Hits	152	Target Neighborhood Hits	84	Shared Neighborhood Hits	4
SwissProt Accessions	Q3UQU0, Q5FWH1, Q811F7	Gene names	Brd9
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 9.

CHD4_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.080508 (rank : 91)
Query Neighborhood Hits	152	Target Neighborhood Hits	365	Shared Neighborhood Hits	47
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD4_MOUSE
θ value	θ > 10 (rank : 175)	NC score	0.081478 (rank : 90)
Query Neighborhood Hits	152	Target Neighborhood Hits	408	Shared Neighborhood Hits	51
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

CHD5_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.078685 (rank : 92)
Query Neighborhood Hits	152	Target Neighborhood Hits	349	Shared Neighborhood Hits	46
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

DPF1_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.110926 (rank : 58)
Query Neighborhood Hits	152	Target Neighborhood Hits	136	Shared Neighborhood Hits	28
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

DPF1_MOUSE
θ value	θ > 10 (rank : 178)	NC score	0.119104 (rank : 52)
Query Neighborhood Hits	152	Target Neighborhood Hits	491	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QX66, Q9QX65, Q9QYA4	Gene names	Dpf1, Neud4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

EPC1_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.051328 (rank : 118)
Query Neighborhood Hits	152	Target Neighborhood Hits	60	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H2F5, Q5VW54, Q5VW56, Q5VW58, Q8NAQ4, Q8NE21, Q96LF4, Q96RR6, Q9H7T7	Gene names	EPC1
Domain Architecture	No domain graphic available
Description	Enhancer of polycomb homolog 1.

MTF2_HUMAN
θ value	θ > 10 (rank : 180)	NC score	0.137012 (rank : 47)
Query Neighborhood Hits	152	Target Neighborhood Hits	119	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y483, Q9UES9, Q9UP40	Gene names	MTF2
Domain Architecture
Description	Metal-response element-binding transcription factor 2 (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

MTF2_MOUSE
θ value	θ > 10 (rank : 181)	NC score	0.141023 (rank : 45)
Query Neighborhood Hits	152	Target Neighborhood Hits	126	Shared Neighborhood Hits	33
SwissProt Accessions	Q02395, Q569Z8, Q6PG89, Q8BGP9, Q8BSJ7	Gene names	Mtf2
Domain Architecture	No domain graphic available
Description	Metal-response element-binding transcription factor 2 (Zinc-regulated factor 1) (ZiRF1) (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

MYST3_MOUSE
θ value	θ > 10 (rank : 182)	NC score	0.104491 (rank : 67)
Query Neighborhood Hits	152	Target Neighborhood Hits	688	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

NSD1_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.100926 (rank : 72)
Query Neighborhood Hits	152	Target Neighborhood Hits	427	Shared Neighborhood Hits	59
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

NSD1_MOUSE
θ value	θ > 10 (rank : 184)	NC score	0.109054 (rank : 61)
Query Neighborhood Hits	152	Target Neighborhood Hits	472	Shared Neighborhood Hits	53
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

PF21A_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.113942 (rank : 53)
Query Neighborhood Hits	152	Target Neighborhood Hits	303	Shared Neighborhood Hits	38
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

PF21A_MOUSE
θ value	θ > 10 (rank : 186)	NC score	0.112517 (rank : 55)
Query Neighborhood Hits	152	Target Neighborhood Hits	285	Shared Neighborhood Hits	35
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

PF21B_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.088021 (rank : 84)
Query Neighborhood Hits	152	Target Neighborhood Hits	197	Shared Neighborhood Hits	26
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PF21B_MOUSE
θ value	θ > 10 (rank : 188)	NC score	0.085981 (rank : 88)
Query Neighborhood Hits	152	Target Neighborhood Hits	278	Shared Neighborhood Hits	33
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PHF10_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.163128 (rank : 37)
Query Neighborhood Hits	152	Target Neighborhood Hits	151	Shared Neighborhood Hits	32
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

PHF10_MOUSE
θ value	θ > 10 (rank : 190)	NC score	0.162652 (rank : 38)
Query Neighborhood Hits	152	Target Neighborhood Hits	131	Shared Neighborhood Hits	29
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

PHF12_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.095269 (rank : 77)
Query Neighborhood Hits	152	Target Neighborhood Hits	174	Shared Neighborhood Hits	29
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF12_MOUSE
θ value	θ > 10 (rank : 192)	NC score	0.093233 (rank : 80)
Query Neighborhood Hits	152	Target Neighborhood Hits	172	Shared Neighborhood Hits	27
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF20_HUMAN
θ value	θ > 10 (rank : 193)	NC score	0.051058 (rank : 119)
Query Neighborhood Hits	152	Target Neighborhood Hits	394	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

PHF20_MOUSE
θ value	θ > 10 (rank : 194)	NC score	0.056000 (rank : 109)
Query Neighborhood Hits	152	Target Neighborhood Hits	513	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

PHF6_HUMAN
θ value	θ > 10 (rank : 195)	NC score	0.093674 (rank : 79)
Query Neighborhood Hits	152	Target Neighborhood Hits	37	Shared Neighborhood Hits	26
SwissProt Accessions	Q8IWS0, Q96JK3, Q9BRU0	Gene names	PHF6, KIAA1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6 (PHD-like zinc finger protein).

PHF6_MOUSE
θ value	θ > 10 (rank : 196)	NC score	0.086616 (rank : 86)
Query Neighborhood Hits	152	Target Neighborhood Hits	39	Shared Neighborhood Hits	27
SwissProt Accessions	Q9D4J7, Q80T86, Q8BYT8, Q8C1B5	Gene names	Phf6, Kiaa1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6.

PKCB1_HUMAN
θ value	θ > 10 (rank : 197)	NC score	0.090618 (rank : 81)
Query Neighborhood Hits	152	Target Neighborhood Hits	488	Shared Neighborhood Hits	45
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

REQU_HUMAN
θ value	θ > 10 (rank : 198)	NC score	0.113517 (rank : 54)
Query Neighborhood Hits	152	Target Neighborhood Hits	523	Shared Neighborhood Hits	29
SwissProt Accessions	Q92785	Gene names	DPF2, REQ, UBID4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

REQU_MOUSE
θ value	θ > 10 (rank : 199)	NC score	0.111885 (rank : 57)
Query Neighborhood Hits	152	Target Neighborhood Hits	519	Shared Neighborhood Hits	29
SwissProt Accessions	Q61103, Q3UNP5, Q60663, Q9QYA3	Gene names	Dpf2, Req, Ubid4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

RSF1_HUMAN
θ value	θ > 10 (rank : 200)	NC score	0.133627 (rank : 48)
Query Neighborhood Hits	152	Target Neighborhood Hits	539	Shared Neighborhood Hits	47
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

SET1A_HUMAN
θ value	θ > 10 (rank : 201)	NC score	0.052765 (rank : 117)
Query Neighborhood Hits	152	Target Neighborhood Hits	690	Shared Neighborhood Hits	54
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

TAF3_HUMAN
θ value	θ > 10 (rank : 202)	NC score	0.103051 (rank : 70)
Query Neighborhood Hits	152	Target Neighborhood Hits	568	Shared Neighborhood Hits	54
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TAF3_MOUSE
θ value	θ > 10 (rank : 203)	NC score	0.100384 (rank : 73)
Query Neighborhood Hits	152	Target Neighborhood Hits	463	Shared Neighborhood Hits	50
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TIF1A_HUMAN
θ value	θ > 10 (rank : 204)	NC score	0.066203 (rank : 101)
Query Neighborhood Hits	152	Target Neighborhood Hits	327	Shared Neighborhood Hits	30
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

TIF1A_MOUSE
θ value	θ > 10 (rank : 205)	NC score	0.064055 (rank : 103)
Query Neighborhood Hits	152	Target Neighborhood Hits	307	Shared Neighborhood Hits	33
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

TIF1B_HUMAN
θ value	θ > 10 (rank : 206)	NC score	0.061765 (rank : 105)
Query Neighborhood Hits	152	Target Neighborhood Hits	312	Shared Neighborhood Hits	25
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TIF1B_MOUSE
θ value	θ > 10 (rank : 207)	NC score	0.066082 (rank : 102)
Query Neighborhood Hits	152	Target Neighborhood Hits	276	Shared Neighborhood Hits	28
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

TIF1G_HUMAN
θ value	θ > 10 (rank : 208)	NC score	0.060297 (rank : 107)
Query Neighborhood Hits	152	Target Neighborhood Hits	410	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TIF1G_MOUSE
θ value	θ > 10 (rank : 209)	NC score	0.063455 (rank : 104)
Query Neighborhood Hits	152	Target Neighborhood Hits	498	Shared Neighborhood Hits	45
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TRI66_HUMAN
θ value	θ > 10 (rank : 210)	NC score	0.070837 (rank : 97)
Query Neighborhood Hits	152	Target Neighborhood Hits	479	Shared Neighborhood Hits	48
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TRI66_MOUSE
θ value	θ > 10 (rank : 211)	NC score	0.071785 (rank : 96)
Query Neighborhood Hits	152	Target Neighborhood Hits	491	Shared Neighborhood Hits	45
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

UHRF1_HUMAN
θ value	θ > 10 (rank : 212)	NC score	0.082614 (rank : 89)
Query Neighborhood Hits	152	Target Neighborhood Hits	272	Shared Neighborhood Hits	22
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

UHRF1_MOUSE
θ value	θ > 10 (rank : 213)	NC score	0.077696 (rank : 93)
Query Neighborhood Hits	152	Target Neighborhood Hits	278	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

UHRF2_HUMAN
θ value	θ > 10 (rank : 214)	NC score	0.090250 (rank : 83)
Query Neighborhood Hits	152	Target Neighborhood Hits	269	Shared Neighborhood Hits	27
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

UHRF2_MOUSE
θ value	θ > 10 (rank : 215)	NC score	0.096517 (rank : 76)
Query Neighborhood Hits	152	Target Neighborhood Hits	275	Shared Neighborhood Hits	29
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

Hits sorted by NC score

JHD3B_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	152	Target Neighborhood Hits	152	Shared Neighborhood Hits	152
SwissProt Accessions	Q91VY5, Q3UR22, Q6ZQ30, Q99K42	Gene names	Jmjd2b, Jhdm3b
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

JHD3B_HUMAN
NC score	0.989189 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	152	Target Neighborhood Hits	128	Shared Neighborhood Hits	71
SwissProt Accessions	O94953, O75274, Q6P3R5, Q9P1V1, Q9UF40	Gene names	JMJD2B, JHDM3B, KIAA0876
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

JHD3C_MOUSE
NC score	0.970555 (rank : 3)	θ value	1.36195e-181 (rank : 4)
Query Neighborhood Hits	152	Target Neighborhood Hits	84	Shared Neighborhood Hits	48
SwissProt Accessions	Q8VCD7, Q3UNP7, Q69ZZ5, Q8BUY6, Q8BWA1	Gene names	Jmjd2c, Jhdm3c, Kiaa0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C).

JHD3A_HUMAN
NC score	0.968156 (rank : 4)	θ value	1.36511e-173 (rank : 5)
Query Neighborhood Hits	152	Target Neighborhood Hits	78	Shared Neighborhood Hits	45
SwissProt Accessions	O75164, Q5VVB1	Gene names	JMJD2A, JHDM3A, JMJD2, KIAA0677
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3A (EC 1.14.11.-) (Jumonji domain-containing protein 2A).

JHD3C_HUMAN
NC score	0.967882 (rank : 5)	θ value	2.48205e-183 (rank : 3)
Query Neighborhood Hits	152	Target Neighborhood Hits	91	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H3R0, O94877, Q2M3M0, Q5JUC9, Q5VYJ2, Q5VYJ3	Gene names	JMJD2C, GASC1, JHDM3C, KIAA0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C) (Gene amplified in squamous cell carcinoma 1 protein) (GASC-1 protein).

JHD3A_MOUSE
NC score	0.967851 (rank : 6)	θ value	1.78289e-173 (rank : 6)
Query Neighborhood Hits	152	Target Neighborhood Hits	85	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BW72, Q3UKM5, Q3UM81, Q3UWV2, Q6ZQ72, Q8K137	Gene names	Jmjd2a, Jhdm3a, Jmjd2, Kiaa0677
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3A (EC 1.14.11.-) (Jumonji domain-containing protein 2A).

JHD3D_MOUSE
NC score	0.875325 (rank : 7)	θ value	5.94893e-161 (rank : 8)
Query Neighborhood Hits	152	Target Neighborhood Hits	20	Shared Neighborhood Hits	16
SwissProt Accessions	Q3U2K5, Q2M1G7, Q8BI19	Gene names	Jmjd2d, Jhdm3d
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3D (EC 1.14.11.-) (Jumonji domain-containing protein 2D).

JHD3D_HUMAN
NC score	0.873684 (rank : 8)	θ value	1.19867e-161 (rank : 7)
Query Neighborhood Hits	152	Target Neighborhood Hits	47	Shared Neighborhood Hits	16
SwissProt Accessions	Q6B0I6, Q9NT41, Q9NW76	Gene names	JMJD2D, JHDM3D
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3D (EC 1.14.11.-) (Jumonji domain-containing protein 2D).

AF17_HUMAN
NC score	0.677251 (rank : 9)	θ value	4.01107e-24 (rank : 17)
Query Neighborhood Hits	152	Target Neighborhood Hits	230	Shared Neighborhood Hits	60
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

AF10_MOUSE
NC score	0.640616 (rank : 10)	θ value	2.59989e-23 (rank : 19)
Query Neighborhood Hits	152	Target Neighborhood Hits	182	Shared Neighborhood Hits	44
SwissProt Accessions	O54826	Gene names	Mllt10, Af10
Domain Architecture
Description	Protein AF-10.

AF10_HUMAN
NC score	0.638133 (rank : 11)	θ value	2.59989e-23 (rank : 18)
Query Neighborhood Hits	152	Target Neighborhood Hits	198	Shared Neighborhood Hits	43
SwissProt Accessions	P55197	Gene names	MLLT10, AF10
Domain Architecture
Description	Protein AF-10.

JAD1D_HUMAN
NC score	0.617957 (rank : 12)	θ value	7.54701e-31 (rank : 10)
Query Neighborhood Hits	152	Target Neighborhood Hits	147	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BY66, Q92509, Q92809, Q9HCU1	Gene names	SMCY, HY, HYA, JARID1D, KIAA0234
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

JAD1A_HUMAN
NC score	0.614736 (rank : 13)	θ value	1.24399e-33 (rank : 9)
Query Neighborhood Hits	152	Target Neighborhood Hits	328	Shared Neighborhood Hits	42
SwissProt Accessions	P29375	Gene names	JARID1A, RBBP2, RBP2
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1A (Retinoblastoma-binding protein 2) (RBBP-2).

JADE3_HUMAN
NC score	0.608137 (rank : 14)	θ value	1.09232e-21 (rank : 24)
Query Neighborhood Hits	152	Target Neighborhood Hits	148	Shared Neighborhood Hits	47
SwissProt Accessions	Q92613, Q6IE79	Gene names	PHF16, JADE3, KIAA0215
Domain Architecture
Description	Protein Jade-3 (PHD finger protein 16).

JADE3_MOUSE
NC score	0.607860 (rank : 15)	θ value	1.09232e-21 (rank : 25)
Query Neighborhood Hits	152	Target Neighborhood Hits	174	Shared Neighborhood Hits	47
SwissProt Accessions	Q6IE82, Q6ZQG2	Gene names	Phf16, Jade3, Kiaa0215
Domain Architecture	No domain graphic available
Description	Protein Jade-3 (PHD finger protein 16).

JAD1C_MOUSE
NC score	0.607318 (rank : 16)	θ value	9.8567e-31 (rank : 13)
Query Neighborhood Hits	152	Target Neighborhood Hits	164	Shared Neighborhood Hits	38
SwissProt Accessions	P41230, O54995, Q9CVI4, Q9D0C3, Q9QVR8, Q9R039	Gene names	Smcx, Jarid1c, Xe169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (SmcX protein) (Xe169 protein).

JAD1C_HUMAN
NC score	0.606681 (rank : 17)	θ value	9.8567e-31 (rank : 12)
Query Neighborhood Hits	152	Target Neighborhood Hits	187	Shared Neighborhood Hits	39
SwissProt Accessions	P41229	Gene names	SMCX, DXS1272E, JARID1C, XE169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (Protein SmcX) (Protein Xe169).

JAD1D_MOUSE
NC score	0.605706 (rank : 18)	θ value	7.54701e-31 (rank : 11)
Query Neighborhood Hits	152	Target Neighborhood Hits	228	Shared Neighborhood Hits	41
SwissProt Accessions	Q62240, Q9QVR9, Q9R040	Gene names	Smcy, Hya, Jarid1d
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

BRPF1_HUMAN
NC score	0.605685 (rank : 19)	θ value	5.40856e-29 (rank : 14)
Query Neighborhood Hits	152	Target Neighborhood Hits	259	Shared Neighborhood Hits	57
SwissProt Accessions	P55201, Q9UHI0	Gene names	BRPF1, BR140
Domain Architecture
Description	Peregrin (Bromodomain and PHD finger-containing protein 1) (BR140 protein).

JADE1_HUMAN
NC score	0.604385 (rank : 20)	θ value	3.75424e-22 (rank : 20)
Query Neighborhood Hits	152	Target Neighborhood Hits	140	Shared Neighborhood Hits	45
SwissProt Accessions	Q6IE81, Q4W5D5, Q6ZSL7, Q8NC41, Q96JL8, Q96SQ1, Q9H692	Gene names	PHF17, JADE1, KIAA1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

JADE1_MOUSE
NC score	0.603519 (rank : 21)	θ value	3.75424e-22 (rank : 21)
Query Neighborhood Hits	152	Target Neighborhood Hits	160	Shared Neighborhood Hits	45
SwissProt Accessions	Q6ZPI0, Q6IE84, Q8C7S6, Q8CFM2, Q8R362	Gene names	Phf17, Jade1, Kiaa1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

JADE2_HUMAN
NC score	0.602935 (rank : 22)	θ value	4.9032e-22 (rank : 23)
Query Neighborhood Hits	152	Target Neighborhood Hits	199	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

PHF14_MOUSE
NC score	0.593763 (rank : 23)	θ value	7.32683e-18 (rank : 27)
Query Neighborhood Hits	152	Target Neighborhood Hits	342	Shared Neighborhood Hits	49
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

BRD1_HUMAN
NC score	0.590690 (rank : 24)	θ value	4.57862e-28 (rank : 15)
Query Neighborhood Hits	152	Target Neighborhood Hits	188	Shared Neighborhood Hits	46
SwissProt Accessions	O95696	Gene names	BRD1, BRL, BRPF2
Domain Architecture
Description	Bromodomain-containing protein 1 (BR140-like protein).

PHF14_HUMAN
NC score	0.582885 (rank : 25)	θ value	7.32683e-18 (rank : 26)
Query Neighborhood Hits	152	Target Neighborhood Hits	447	Shared Neighborhood Hits	52
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

BRPF3_HUMAN
NC score	0.572642 (rank : 26)	θ value	4.73814e-25 (rank : 16)
Query Neighborhood Hits	152	Target Neighborhood Hits	217	Shared Neighborhood Hits	49
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

JADE2_MOUSE
NC score	0.572233 (rank : 27)	θ value	3.75424e-22 (rank : 22)
Query Neighborhood Hits	152	Target Neighborhood Hits	560	Shared Neighborhood Hits	70
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

JARD2_MOUSE
NC score	0.548000 (rank : 28)	θ value	1.80466e-16 (rank : 28)
Query Neighborhood Hits	152	Target Neighborhood Hits	169	Shared Neighborhood Hits	25
SwissProt Accessions	Q62315, Q99LD1	Gene names	Jarid2, Jmj
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

JARD2_HUMAN
NC score	0.543935 (rank : 29)	θ value	2.60593e-15 (rank : 29)
Query Neighborhood Hits	152	Target Neighborhood Hits	119	Shared Neighborhood Hits	23
SwissProt Accessions	Q92833, Q5U5L5	Gene names	JARID2, JMJ
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

PHF11_HUMAN
NC score	0.208457 (rank : 30)	θ value	0.0193708 (rank : 38)
Query Neighborhood Hits	152	Target Neighborhood Hits	42	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UIL8, Q9Y5A2	Gene names	PHF11, BCAP
Domain Architecture	No domain graphic available
Description	PHD finger protein 11 (BRCA1 C-terminus-associated protein) (NY-REN-34 antigen).

MLL4_HUMAN
NC score	0.199835 (rank : 31)	θ value	0.00134147 (rank : 32)
Query Neighborhood Hits	152	Target Neighborhood Hits	722	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

MLL3_MOUSE
NC score	0.189551 (rank : 32)	θ value	0.00175202 (rank : 33)
Query Neighborhood Hits	152	Target Neighborhood Hits	1399	Shared Neighborhood Hits	89
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

PHF7_MOUSE
NC score	0.189309 (rank : 33)	θ value	0.47712 (rank : 51)
Query Neighborhood Hits	152	Target Neighborhood Hits	65	Shared Neighborhood Hits	39
SwissProt Accessions	Q9DAG9, Q6PG81	Gene names	Phf7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

MLL2_HUMAN
NC score	0.176959 (rank : 34)	θ value	3.0926 (rank : 101)
Query Neighborhood Hits	152	Target Neighborhood Hits	1788	Shared Neighborhood Hits	106
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

HRX_HUMAN
NC score	0.176779 (rank : 35)	θ value	0.00509761 (rank : 35)
Query Neighborhood Hits	152	Target Neighborhood Hits	825	Shared Neighborhood Hits	82
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

MLL3_HUMAN
NC score	0.176144 (rank : 36)	θ value	0.00298849 (rank : 34)
Query Neighborhood Hits	152	Target Neighborhood Hits	1644	Shared Neighborhood Hits	95
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

PHF10_HUMAN
NC score	0.163128 (rank : 37)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	152	Target Neighborhood Hits	151	Shared Neighborhood Hits	32
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

PHF10_MOUSE
NC score	0.162652 (rank : 38)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	152	Target Neighborhood Hits	131	Shared Neighborhood Hits	29
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

PHF1_MOUSE
NC score	0.155028 (rank : 39)	θ value	1.81305 (rank : 85)
Query Neighborhood Hits	152	Target Neighborhood Hits	116	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Z1B8, O54808	Gene names	Phf1, Tctex-3, Tctex3
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1) (T-complex testis-expressed 3) (Polycomblike 1) (mPCl1).

PHF1_HUMAN
NC score	0.154352 (rank : 40)	θ value	1.81305 (rank : 84)
Query Neighborhood Hits	152	Target Neighborhood Hits	117	Shared Neighborhood Hits	32
SwissProt Accessions	O43189, O60929, Q96KM7	Gene names	PHF1
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1).

AIRE_HUMAN
NC score	0.153383 (rank : 41)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	152	Target Neighborhood Hits	144	Shared Neighborhood Hits	34
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

PHF7_HUMAN
NC score	0.149262 (rank : 42)	θ value	1.06291 (rank : 66)
Query Neighborhood Hits	152	Target Neighborhood Hits	71	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BWX1	Gene names	PHF7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

RAI1_MOUSE
NC score	0.147892 (rank : 43)	θ value	0.0736092 (rank : 39)
Query Neighborhood Hits	152	Target Neighborhood Hits	344	Shared Neighborhood Hits	58
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

AIRE_MOUSE
NC score	0.144106 (rank : 44)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	152	Target Neighborhood Hits	196	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

MTF2_MOUSE
NC score	0.141023 (rank : 45)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	152	Target Neighborhood Hits	126	Shared Neighborhood Hits	33
SwissProt Accessions	Q02395, Q569Z8, Q6PG89, Q8BGP9, Q8BSJ7	Gene names	Mtf2
Domain Architecture	No domain graphic available
Description	Metal-response element-binding transcription factor 2 (Zinc-regulated factor 1) (ZiRF1) (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

RAI1_HUMAN
NC score	0.137556 (rank : 46)	θ value	0.62314 (rank : 59)
Query Neighborhood Hits	152	Target Neighborhood Hits	360	Shared Neighborhood Hits	50
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

MTF2_HUMAN
NC score	0.137012 (rank : 47)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	152	Target Neighborhood Hits	119	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y483, Q9UES9, Q9UP40	Gene names	MTF2
Domain Architecture
Description	Metal-response element-binding transcription factor 2 (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

RSF1_HUMAN
NC score	0.133627 (rank : 48)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	152	Target Neighborhood Hits	539	Shared Neighborhood Hits	47
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

BAZ1B_MOUSE
NC score	0.130647 (rank : 49)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	152	Target Neighborhood Hits	394	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

BAZ1A_HUMAN
NC score	0.123031 (rank : 50)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	152	Target Neighborhood Hits	693	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

BAZ1B_HUMAN
NC score	0.122585 (rank : 51)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	152	Target Neighborhood Hits	701	Shared Neighborhood Hits	48
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

DPF1_MOUSE
NC score	0.119104 (rank : 52)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	152	Target Neighborhood Hits	491	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QX66, Q9QX65, Q9QYA4	Gene names	Dpf1, Neud4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

PF21A_HUMAN
NC score	0.113942 (rank : 53)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	152	Target Neighborhood Hits	303	Shared Neighborhood Hits	38
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

REQU_HUMAN
NC score	0.113517 (rank : 54)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	152	Target Neighborhood Hits	523	Shared Neighborhood Hits	29
SwissProt Accessions	Q92785	Gene names	DPF2, REQ, UBID4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

PF21A_MOUSE
NC score	0.112517 (rank : 55)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	152	Target Neighborhood Hits	285	Shared Neighborhood Hits	35
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

BAZ2A_HUMAN
NC score	0.112326 (rank : 56)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	152	Target Neighborhood Hits	780	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

REQU_MOUSE
NC score	0.111885 (rank : 57)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	152	Target Neighborhood Hits	519	Shared Neighborhood Hits	29
SwissProt Accessions	Q61103, Q3UNP5, Q60663, Q9QYA3	Gene names	Dpf2, Req, Ubid4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

DPF1_HUMAN
NC score	0.110926 (rank : 58)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	152	Target Neighborhood Hits	136	Shared Neighborhood Hits	28
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

BAZ2A_MOUSE
NC score	0.110606 (rank : 59)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	152	Target Neighborhood Hits	744	Shared Neighborhood Hits	61
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

MYST3_HUMAN
NC score	0.110419 (rank : 60)	θ value	8.99809 (rank : 146)
Query Neighborhood Hits	152	Target Neighborhood Hits	772	Shared Neighborhood Hits	68
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

NSD1_MOUSE
NC score	0.109054 (rank : 61)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	152	Target Neighborhood Hits	472	Shared Neighborhood Hits	53
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

ARI3A_HUMAN
NC score	0.108384 (rank : 62)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	152	Target Neighborhood Hits	80	Shared Neighborhood Hits	16
SwissProt Accessions	Q99856, Q8IZA7	Gene names	ARID3A, DRIL1, DRX, E2FBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 3A (ARID domain- containing protein 3A) (B-cell regulator of IgH transcription) (Bright) (E2F-binding protein 1).

ARI3A_MOUSE
NC score	0.108180 (rank : 63)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	152	Target Neighborhood Hits	64	Shared Neighborhood Hits	9
SwissProt Accessions	Q62431	Gene names	Arid3a, Dri1, Dril1
Domain Architecture
Description	AT-rich interactive domain-containing protein 3A (ARID domain- containing protein 3A) (Dead ringer-like protein 1) (B-cell regulator of IgH transcription) (Bright).

MYST4_HUMAN
NC score	0.107488 (rank : 64)	θ value	1.38821 (rank : 73)
Query Neighborhood Hits	152	Target Neighborhood Hits	671	Shared Neighborhood Hits	55
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

MYST4_MOUSE
NC score	0.107369 (rank : 65)	θ value	1.38821 (rank : 74)
Query Neighborhood Hits	152	Target Neighborhood Hits	416	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

TCF20_HUMAN
NC score	0.106963 (rank : 66)	θ value	0.47712 (rank : 52)
Query Neighborhood Hits	152	Target Neighborhood Hits	323	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

MYST3_MOUSE
NC score	0.104491 (rank : 67)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	152	Target Neighborhood Hits	688	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

BAZ2B_HUMAN
NC score	0.103676 (rank : 68)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	152	Target Neighborhood Hits	803	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

BPTF_HUMAN
NC score	0.103059 (rank : 69)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	152	Target Neighborhood Hits	786	Shared Neighborhood Hits	63
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

TAF3_HUMAN
NC score	0.103051 (rank : 70)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	152	Target Neighborhood Hits	568	Shared Neighborhood Hits	54
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TCF20_MOUSE
NC score	0.102247 (rank : 71)	θ value	0.47712 (rank : 53)
Query Neighborhood Hits	152	Target Neighborhood Hits	396	Shared Neighborhood Hits	50
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

NSD1_HUMAN
NC score	0.100926 (rank : 72)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	152	Target Neighborhood Hits	427	Shared Neighborhood Hits	59
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

TAF3_MOUSE
NC score	0.100384 (rank : 73)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	152	Target Neighborhood Hits	463	Shared Neighborhood Hits	50
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

K1333_MOUSE
NC score	0.100042 (rank : 74)	θ value	2.36792 (rank : 91)
Query Neighborhood Hits	152	Target Neighborhood Hits	53	Shared Neighborhood Hits	28
SwissProt Accessions	Q5RJY2, Q6ZPT7, Q8BNA4	Gene names	Kiaa1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

ARI4A_HUMAN
NC score	0.097491 (rank : 75)	θ value	0.813845 (rank : 61)
Query Neighborhood Hits	152	Target Neighborhood Hits	434	Shared Neighborhood Hits	20
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

UHRF2_MOUSE
NC score	0.096517 (rank : 76)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	152	Target Neighborhood Hits	275	Shared Neighborhood Hits	29
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

PHF12_HUMAN
NC score	0.095269 (rank : 77)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	152	Target Neighborhood Hits	174	Shared Neighborhood Hits	29
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

LBR_HUMAN
NC score	0.094599 (rank : 78)	θ value	0.21417 (rank : 44)
Query Neighborhood Hits	152	Target Neighborhood Hits	25	Shared Neighborhood Hits	8
SwissProt Accessions	Q14739, Q14740, Q53GU7, Q59FE6	Gene names	LBR
Domain Architecture
Description	Lamin-B receptor (Integral nuclear envelope inner membrane protein) (LMN2R).

PHF6_HUMAN
NC score	0.093674 (rank : 79)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	152	Target Neighborhood Hits	37	Shared Neighborhood Hits	26
SwissProt Accessions	Q8IWS0, Q96JK3, Q9BRU0	Gene names	PHF6, KIAA1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6 (PHD-like zinc finger protein).

PHF12_MOUSE
NC score	0.093233 (rank : 80)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	152	Target Neighborhood Hits	172	Shared Neighborhood Hits	27
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PKCB1_HUMAN
NC score	0.090618 (rank : 81)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	152	Target Neighborhood Hits	488	Shared Neighborhood Hits	45
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

LBR_MOUSE
NC score	0.090539 (rank : 82)	θ value	0.62314 (rank : 57)
Query Neighborhood Hits	152	Target Neighborhood Hits	23	Shared Neighborhood Hits	8
SwissProt Accessions	Q3U9G9, Q3TSW2, Q811V8, Q811V9, Q8BST3, Q8K2Y8, Q8VDM0, Q91YS5, Q91Z27	Gene names	Lbr
Domain Architecture	No domain graphic available
Description	Lamin-B receptor (Integral nuclear envelope inner membrane protein).

UHRF2_HUMAN
NC score	0.090250 (rank : 83)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	152	Target Neighborhood Hits	269	Shared Neighborhood Hits	27
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

PF21B_HUMAN
NC score	0.088021 (rank : 84)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	152	Target Neighborhood Hits	197	Shared Neighborhood Hits	26
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

CHD3_HUMAN
NC score	0.086701 (rank : 85)	θ value	8.99809 (rank : 142)
Query Neighborhood Hits	152	Target Neighborhood Hits	397	Shared Neighborhood Hits	52
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

PHF6_MOUSE
NC score	0.086616 (rank : 86)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	152	Target Neighborhood Hits	39	Shared Neighborhood Hits	27
SwissProt Accessions	Q9D4J7, Q80T86, Q8BYT8, Q8C1B5	Gene names	Phf6, Kiaa1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6.

ARID2_HUMAN
NC score	0.086227 (rank : 87)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	152	Target Neighborhood Hits	302	Shared Neighborhood Hits	27
SwissProt Accessions	Q68CP9, Q5EB51, Q645I3, Q6ZRY5, Q7Z3I5, Q86T28, Q96SJ6, Q9HCL5	Gene names	ARID2, KIAA1557
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 2 (ARID domain- containing protein 2) (BRG1-associated factor 200) (BAF200).

PF21B_MOUSE
NC score	0.085981 (rank : 88)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	152	Target Neighborhood Hits	278	Shared Neighborhood Hits	33
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

UHRF1_HUMAN
NC score	0.082614 (rank : 89)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	152	Target Neighborhood Hits	272	Shared Neighborhood Hits	22
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

CHD4_MOUSE
NC score	0.081478 (rank : 90)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	152	Target Neighborhood Hits	408	Shared Neighborhood Hits	51
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

CHD4_HUMAN
NC score	0.080508 (rank : 91)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	152	Target Neighborhood Hits	365	Shared Neighborhood Hits	47
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD5_HUMAN
NC score	0.078685 (rank : 92)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	152	Target Neighborhood Hits	349	Shared Neighborhood Hits	46
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

UHRF1_MOUSE
NC score	0.077696 (rank : 93)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	152	Target Neighborhood Hits	278	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

ARI1B_HUMAN
NC score	0.076110 (rank : 94)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	152	Target Neighborhood Hits	567	Shared Neighborhood Hits	47
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

K1333_HUMAN
NC score	0.074643 (rank : 95)	θ value	5.27518 (rank : 118)
Query Neighborhood Hits	152	Target Neighborhood Hits	50	Shared Neighborhood Hits	28
SwissProt Accessions	Q7L622, Q9BVR2, Q9H9E9, Q9NXC0, Q9P2L3	Gene names	KIAA1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

TRI66_MOUSE
NC score	0.071785 (rank : 96)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	152	Target Neighborhood Hits	491	Shared Neighborhood Hits	45
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TRI66_HUMAN
NC score	0.070837 (rank : 97)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	152	Target Neighborhood Hits	479	Shared Neighborhood Hits	48
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

ARI5B_HUMAN
NC score	0.069616 (rank : 98)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	152	Target Neighborhood Hits	328	Shared Neighborhood Hits	31
SwissProt Accessions	Q14865, Q7Z3M4, Q8N421, Q9H786	Gene names	ARID5B, DESRT, MRF2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (Mrf1-like) (Modulator recognition factor 2) (MRF-2).

ARI5B_MOUSE
NC score	0.068729 (rank : 99)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	152	Target Neighborhood Hits	158	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BM75, Q8C0E0, Q8K4G8, Q8K4L9, Q9CU78, Q9JIX4	Gene names	Arid5b, Desrt, Mrf2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (MRF1-like) (Modulator recognition factor protein 2) (MRF-2) (Developmentally and sexually retarded with transient immune abnormalities protein).

ARI1A_HUMAN
NC score	0.068585 (rank : 100)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	152	Target Neighborhood Hits	787	Shared Neighborhood Hits	50
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

TIF1A_HUMAN
NC score	0.066203 (rank : 101)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	152	Target Neighborhood Hits	327	Shared Neighborhood Hits	30
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

TIF1B_MOUSE
NC score	0.066082 (rank : 102)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	152	Target Neighborhood Hits	276	Shared Neighborhood Hits	28
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

TIF1A_MOUSE
NC score	0.064055 (rank : 103)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	152	Target Neighborhood Hits	307	Shared Neighborhood Hits	33
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

TIF1G_MOUSE
NC score	0.063455 (rank : 104)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	152	Target Neighborhood Hits	498	Shared Neighborhood Hits	45
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TIF1B_HUMAN
NC score	0.061765 (rank : 105)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	152	Target Neighborhood Hits	312	Shared Neighborhood Hits	25
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TXND2_HUMAN
NC score	0.061089 (rank : 106)	θ value	0.000461057 (rank : 31)
Query Neighborhood Hits	152	Target Neighborhood Hits	793	Shared Neighborhood Hits	51
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

TIF1G_HUMAN
NC score	0.060297 (rank : 107)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	152	Target Neighborhood Hits	410	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

BRD9_HUMAN
NC score	0.056478 (rank : 108)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	152	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H8M2, Q2XUS1, Q6UWU9, Q8IUS4, Q9H5Q5, Q9H7R9	Gene names	BRD9
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 9 (Rhabdomyosarcoma antigen MU-RMS- 40.8).

PHF20_MOUSE
NC score	0.056000 (rank : 109)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	152	Target Neighborhood Hits	513	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

BRD7_HUMAN
NC score	0.055498 (rank : 110)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	152	Target Neighborhood Hits	94	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NPI1, Q4VC09, Q8N2L9, Q96KA4, Q9BV48, Q9UH59	Gene names	BRD7, BP75, CELTIX1
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein) (Protein CELTIX-1).

BRD7_MOUSE
NC score	0.054528 (rank : 111)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	152	Target Neighborhood Hits	141	Shared Neighborhood Hits	8
SwissProt Accessions	O88665, Q3UQ56, Q3UU06, Q9CT78	Gene names	Brd7, Bp75
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein).

BASP_HUMAN
NC score	0.054353 (rank : 112)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	152	Target Neighborhood Hits	321	Shared Neighborhood Hits	43
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BRD9_MOUSE
NC score	0.054153 (rank : 113)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	152	Target Neighborhood Hits	84	Shared Neighborhood Hits	4
SwissProt Accessions	Q3UQU0, Q5FWH1, Q811F7	Gene names	Brd9
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 9.

NACAM_MOUSE
NC score	0.054075 (rank : 114)	θ value	0.62314 (rank : 58)
Query Neighborhood Hits	152	Target Neighborhood Hits	1866	Shared Neighborhood Hits	85
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

MDC1_MOUSE
NC score	0.053710 (rank : 115)	θ value	0.163984 (rank : 41)
Query Neighborhood Hits	152	Target Neighborhood Hits	998	Shared Neighborhood Hits	67
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

CJ012_HUMAN
NC score	0.053685 (rank : 116)	θ value	0.813845 (rank : 63)
Query Neighborhood Hits	152	Target Neighborhood Hits	467	Shared Neighborhood Hits	41
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

SET1A_HUMAN
NC score	0.052765 (rank : 117)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	152	Target Neighborhood Hits	690	Shared Neighborhood Hits	54
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

EPC1_HUMAN
NC score	0.051328 (rank : 118)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	152	Target Neighborhood Hits	60	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H2F5, Q5VW54, Q5VW56, Q5VW58, Q8NAQ4, Q8NE21, Q96LF4, Q96RR6, Q9H7T7	Gene names	EPC1
Domain Architecture	No domain graphic available
Description	Enhancer of polycomb homolog 1.

PHF20_HUMAN
NC score	0.051058 (rank : 119)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	152	Target Neighborhood Hits	394	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

OGFR_HUMAN
NC score	0.050936 (rank : 120)	θ value	0.00869519 (rank : 36)
Query Neighborhood Hits	152	Target Neighborhood Hits	1582	Shared Neighborhood Hits	66
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

NFH_MOUSE
NC score	0.049232 (rank : 121)	θ value	5.81887e-07 (rank : 30)
Query Neighborhood Hits	152	Target Neighborhood Hits	2247	Shared Neighborhood Hits	88
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PHF13_MOUSE
NC score	0.045321 (rank : 122)	θ value	4.03905 (rank : 113)
Query Neighborhood Hits	152	Target Neighborhood Hits	42	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K2W6	Gene names	Phf13
Domain Architecture
Description	PHD finger protein 13.

PHF13_HUMAN
NC score	0.045263 (rank : 123)	θ value	4.03905 (rank : 112)
Query Neighborhood Hits	152	Target Neighborhood Hits	41	Shared Neighborhood Hits	10
SwissProt Accessions	Q86YI8, Q8N551, Q9UJP2	Gene names	PHF13
Domain Architecture
Description	PHD finger protein 13.

TCOF_HUMAN
NC score	0.043402 (rank : 124)	θ value	8.99809 (rank : 151)
Query Neighborhood Hits	152	Target Neighborhood Hits	543	Shared Neighborhood Hits	45
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

CU121_HUMAN
NC score	0.043103 (rank : 125)	θ value	0.62314 (rank : 55)
Query Neighborhood Hits	152	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N0V1	Gene names	C21orf121
Domain Architecture	No domain graphic available
Description	Protein C21orf121.

SON_HUMAN
NC score	0.041817 (rank : 126)	θ value	0.163984 (rank : 43)
Query Neighborhood Hits	152	Target Neighborhood Hits	1568	Shared Neighborhood Hits	63
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

NIPBL_HUMAN
NC score	0.040528 (rank : 127)	θ value	1.38821 (rank : 75)
Query Neighborhood Hits	152	Target Neighborhood Hits	1311	Shared Neighborhood Hits	58
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

AFF4_MOUSE
NC score	0.039865 (rank : 128)	θ value	0.163984 (rank : 40)
Query Neighborhood Hits	152	Target Neighborhood Hits	581	Shared Neighborhood Hits	38
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

ATN1_HUMAN
NC score	0.039369 (rank : 129)	θ value	5.27518 (rank : 116)
Query Neighborhood Hits	152	Target Neighborhood Hits	676	Shared Neighborhood Hits	47
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

MDC1_HUMAN
NC score	0.037300 (rank : 130)	θ value	8.99809 (rank : 145)
Query Neighborhood Hits	152	Target Neighborhood Hits	1446	Shared Neighborhood Hits	62
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

PRRT3_HUMAN
NC score	0.035366 (rank : 131)	θ value	2.36792 (rank : 94)
Query Neighborhood Hits	152	Target Neighborhood Hits	998	Shared Neighborhood Hits	50
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

FA21C_HUMAN
NC score	0.035006 (rank : 132)	θ value	0.365318 (rank : 48)
Query Neighborhood Hits	152	Target Neighborhood Hits	194	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y4E1, Q5SQU4, Q5SQU5, Q7L521, Q9UG79	Gene names	FAM21C, KIAA0592
Domain Architecture	No domain graphic available
Description	Protein FAM21C.

TARSH_HUMAN
NC score	0.034343 (rank : 133)	θ value	6.88961 (rank : 138)
Query Neighborhood Hits	152	Target Neighborhood Hits	768	Shared Neighborhood Hits	51
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

MILK1_MOUSE
NC score	0.033084 (rank : 134)	θ value	5.27518 (rank : 123)
Query Neighborhood Hits	152	Target Neighborhood Hits	788	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

ARMX2_MOUSE
NC score	0.031754 (rank : 135)	θ value	0.365318 (rank : 47)
Query Neighborhood Hits	152	Target Neighborhood Hits	349	Shared Neighborhood Hits	27
SwissProt Accessions	Q6A058, Q9CXI9	Gene names	Armcx2, Kiaa0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2.

MINT_MOUSE
NC score	0.031698 (rank : 136)	θ value	3.0926 (rank : 100)
Query Neighborhood Hits	152	Target Neighborhood Hits	1514	Shared Neighborhood Hits	70
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

DPCA2_HUMAN
NC score	0.030703 (rank : 137)	θ value	1.81305 (rank : 81)
Query Neighborhood Hits	152	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q86SG4, Q86SH8, Q8N8I5	Gene names	C15orf21
Domain Architecture	No domain graphic available
Description	Dresden prostate carcinoma 2 protein (D-PCa-2).

RGS3_MOUSE
NC score	0.030133 (rank : 138)	θ value	0.163984 (rank : 42)
Query Neighborhood Hits	152	Target Neighborhood Hits	1621	Shared Neighborhood Hits	63
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

ZN750_MOUSE
NC score	0.028925 (rank : 139)	θ value	3.0926 (rank : 106)
Query Neighborhood Hits	152	Target Neighborhood Hits	346	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

AMPH_HUMAN
NC score	0.028878 (rank : 140)	θ value	0.365318 (rank : 46)
Query Neighborhood Hits	152	Target Neighborhood Hits	455	Shared Neighborhood Hits	31
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

HSF1_MOUSE
NC score	0.028790 (rank : 141)	θ value	0.365318 (rank : 49)
Query Neighborhood Hits	152	Target Neighborhood Hits	267	Shared Neighborhood Hits	21
SwissProt Accessions	P38532, O70462	Gene names	Hsf1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

NCOR2_MOUSE
NC score	0.028623 (rank : 142)	θ value	2.36792 (rank : 93)
Query Neighborhood Hits	152	Target Neighborhood Hits	790	Shared Neighborhood Hits	48
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

K1802_HUMAN
NC score	0.028424 (rank : 143)	θ value	1.81305 (rank : 82)
Query Neighborhood Hits	152	Target Neighborhood Hits	1378	Shared Neighborhood Hits	63
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

K1802_MOUSE
NC score	0.027813 (rank : 144)	θ value	2.36792 (rank : 92)
Query Neighborhood Hits	152	Target Neighborhood Hits	1596	Shared Neighborhood Hits	68
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

WDR24_HUMAN
NC score	0.027532 (rank : 145)	θ value	0.813845 (rank : 64)
Query Neighborhood Hits	152	Target Neighborhood Hits	247	Shared Neighborhood Hits	5
SwissProt Accessions	Q96S15, Q96GC7, Q9H0B7	Gene names	WDR24
Domain Architecture	No domain graphic available
Description	WD repeat protein 24.

TAU_MOUSE
NC score	0.027468 (rank : 146)	θ value	5.27518 (rank : 125)
Query Neighborhood Hits	152	Target Neighborhood Hits	502	Shared Neighborhood Hits	39
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

APXL_HUMAN
NC score	0.027399 (rank : 147)	θ value	1.38821 (rank : 70)
Query Neighborhood Hits	152	Target Neighborhood Hits	553	Shared Neighborhood Hits	30
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

RBBP6_MOUSE
NC score	0.027338 (rank : 148)	θ value	1.38821 (rank : 77)
Query Neighborhood Hits	152	Target Neighborhood Hits	1014	Shared Neighborhood Hits	41
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

SC24C_HUMAN
NC score	0.026811 (rank : 149)	θ value	0.62314 (rank : 60)
Query Neighborhood Hits	152	Target Neighborhood Hits	662	Shared Neighborhood Hits	37
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

RGS3_HUMAN
NC score	0.025585 (rank : 150)	θ value	6.88961 (rank : 133)
Query Neighborhood Hits	152	Target Neighborhood Hits	1375	Shared Neighborhood Hits	55
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

SRCA_HUMAN
NC score	0.025554 (rank : 151)	θ value	6.88961 (rank : 137)
Query Neighborhood Hits	152	Target Neighborhood Hits	380	Shared Neighborhood Hits	34
SwissProt Accessions	Q86TD4	Gene names	SRL
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

ASXL1_HUMAN
NC score	0.025446 (rank : 152)	θ value	0.813845 (rank : 62)
Query Neighborhood Hits	152	Target Neighborhood Hits	260	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IXJ9, Q5JWS9, Q8IYY7, Q9H466, Q9NQF8, Q9UFJ0, Q9UFP8, Q9Y2I4	Gene names	ASXL1, KIAA0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

ALO17_HUMAN
NC score	0.025177 (rank : 153)	θ value	6.88961 (rank : 128)
Query Neighborhood Hits	152	Target Neighborhood Hits	317	Shared Neighborhood Hits	24
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

PSL1_HUMAN
NC score	0.023186 (rank : 154)	θ value	1.38821 (rank : 76)
Query Neighborhood Hits	152	Target Neighborhood Hits	650	Shared Neighborhood Hits	33
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

PI5PA_MOUSE
NC score	0.022952 (rank : 155)	θ value	6.88961 (rank : 132)
Query Neighborhood Hits	152	Target Neighborhood Hits	331	Shared Neighborhood Hits	39
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

MAGE1_HUMAN
NC score	0.022640 (rank : 156)	θ value	5.27518 (rank : 120)
Query Neighborhood Hits	152	Target Neighborhood Hits	1389	Shared Neighborhood Hits	64
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

GRIN1_HUMAN
NC score	0.021860 (rank : 157)	θ value	4.03905 (rank : 109)
Query Neighborhood Hits	152	Target Neighborhood Hits	681	Shared Neighborhood Hits	39
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

WDR24_MOUSE
NC score	0.021673 (rank : 158)	θ value	0.813845 (rank : 65)
Query Neighborhood Hits	152	Target Neighborhood Hits	286	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CFJ9	Gene names	Wdr24
Domain Architecture	No domain graphic available
Description	WD repeat protein 24.

LIMD1_MOUSE
NC score	0.021544 (rank : 159)	θ value	0.0148317 (rank : 37)
Query Neighborhood Hits	152	Target Neighborhood Hits	291	Shared Neighborhood Hits	15
SwissProt Accessions	Q9QXD8, Q8C8G4, Q9CW55	Gene names	Limd1
Domain Architecture
Description	LIM domain-containing protein 1.

EVL_HUMAN
NC score	0.021407 (rank : 160)	θ value	2.36792 (rank : 90)
Query Neighborhood Hits	152	Target Neighborhood Hits	260	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UI08, O95884, Q7Z522, Q8TBV1, Q9UF25, Q9UIC2	Gene names	EVL, RNB6
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

K1683_HUMAN
NC score	0.019542 (rank : 161)	θ value	5.27518 (rank : 119)
Query Neighborhood Hits	152	Target Neighborhood Hits	240	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

ZN645_HUMAN
NC score	0.019349 (rank : 162)	θ value	4.03905 (rank : 115)
Query Neighborhood Hits	152	Target Neighborhood Hits	265	Shared Neighborhood Hits	14
SwissProt Accessions	Q8N7E2, Q6DJY9	Gene names	ZNF645
Domain Architecture	No domain graphic available
Description	Zinc finger protein 645.

AL2S8_MOUSE
NC score	0.018936 (rank : 163)	θ value	1.38821 (rank : 69)
Query Neighborhood Hits	152	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VHI4	Gene names	Als2cr8, Carf
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein homolog (Calcium-response factor) (CaRF).

CP053_MOUSE
NC score	0.017975 (rank : 164)	θ value	3.0926 (rank : 97)
Query Neighborhood Hits	152	Target Neighborhood Hits	38	Shared Neighborhood Hits	6
SwissProt Accessions	Q99L02	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf53 homolog.

ASPP1_MOUSE
NC score	0.017874 (rank : 165)	θ value	4.03905 (rank : 107)
Query Neighborhood Hits	152	Target Neighborhood Hits	1244	Shared Neighborhood Hits	53
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

RRBP1_HUMAN
NC score	0.017420 (rank : 166)	θ value	1.81305 (rank : 86)
Query Neighborhood Hits	152	Target Neighborhood Hits	1306	Shared Neighborhood Hits	35
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

ETV3_HUMAN
NC score	0.017170 (rank : 167)	θ value	3.0926 (rank : 99)
Query Neighborhood Hits	152	Target Neighborhood Hits	312	Shared Neighborhood Hits	29
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

SRBP1_MOUSE
NC score	0.016748 (rank : 168)	θ value	5.27518 (rank : 124)
Query Neighborhood Hits	152	Target Neighborhood Hits	384	Shared Neighborhood Hits	24
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

WHRN_MOUSE
NC score	0.016276 (rank : 169)	θ value	2.36792 (rank : 95)
Query Neighborhood Hits	152	Target Neighborhood Hits	412	Shared Neighborhood Hits	26
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

CEL_HUMAN
NC score	0.015614 (rank : 170)	θ value	0.62314 (rank : 54)
Query Neighborhood Hits	152	Target Neighborhood Hits	896	Shared Neighborhood Hits	35
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

CSKI1_HUMAN
NC score	0.015355 (rank : 171)	θ value	8.99809 (rank : 143)
Query Neighborhood Hits	152	Target Neighborhood Hits	997	Shared Neighborhood Hits	55
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

SSBP4_HUMAN
NC score	0.015255 (rank : 172)	θ value	1.06291 (rank : 68)
Query Neighborhood Hits	152	Target Neighborhood Hits	753	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

EPN3_HUMAN
NC score	0.014691 (rank : 173)	θ value	3.0926 (rank : 98)
Query Neighborhood Hits	152	Target Neighborhood Hits	197	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H201, Q9BVN6, Q9NWK2	Gene names	EPN3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

DOK2_MOUSE
NC score	0.014677 (rank : 174)	θ value	2.36792 (rank : 88)
Query Neighborhood Hits	152	Target Neighborhood Hits	244	Shared Neighborhood Hits	16
SwissProt Accessions	O70469, O70272, Q99KL1	Gene names	Dok2, Frip
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)) (Dok- related protein) (Dok-R) (IL-four receptor-interacting protein) (FRIP).

RRBP1_MOUSE
NC score	0.014621 (rank : 175)	θ value	3.0926 (rank : 104)
Query Neighborhood Hits	152	Target Neighborhood Hits	1650	Shared Neighborhood Hits	41
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

ANC1_MOUSE
NC score	0.014604 (rank : 176)	θ value	1.81305 (rank : 78)
Query Neighborhood Hits	152	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	P53995, Q8BP33, Q8C772	Gene names	Anapc1, Mcpr, Tsg24
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Protein Tsg24) (Mitotic checkpoint regulator).

SDPR_HUMAN
NC score	0.014343 (rank : 177)	θ value	6.88961 (rank : 136)
Query Neighborhood Hits	152	Target Neighborhood Hits	337	Shared Neighborhood Hits	12
SwissProt Accessions	O95810	Gene names	SDPR
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein) (PS-p68).

GNAS1_HUMAN
NC score	0.014311 (rank : 178)	θ value	4.03905 (rank : 108)
Query Neighborhood Hits	152	Target Neighborhood Hits	278	Shared Neighborhood Hits	29
SwissProt Accessions	Q5JWF2, O75684, O75685, Q5JW67, Q5JWF1, Q9NY42	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

SYNPO_HUMAN
NC score	0.013980 (rank : 179)	θ value	8.99809 (rank : 150)
Query Neighborhood Hits	152	Target Neighborhood Hits	281	Shared Neighborhood Hits	24
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

E41L3_MOUSE
NC score	0.013452 (rank : 180)	θ value	0.62314 (rank : 56)
Query Neighborhood Hits	152	Target Neighborhood Hits	250	Shared Neighborhood Hits	11
SwissProt Accessions	Q9WV92, Q9R102	Gene names	Epb41l3, Dal1, Epb4.1l3
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1).

GA2L2_MOUSE
NC score	0.012837 (rank : 181)	θ value	6.88961 (rank : 131)
Query Neighborhood Hits	152	Target Neighborhood Hits	395	Shared Neighborhood Hits	25
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

NFM_HUMAN
NC score	0.012282 (rank : 182)	θ value	3.0926 (rank : 102)
Query Neighborhood Hits	152	Target Neighborhood Hits	1328	Shared Neighborhood Hits	49
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

LPP_HUMAN
NC score	0.012147 (rank : 183)	θ value	8.99809 (rank : 144)
Query Neighborhood Hits	152	Target Neighborhood Hits	775	Shared Neighborhood Hits	37
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

PTN22_MOUSE
NC score	0.011934 (rank : 184)	θ value	0.279714 (rank : 45)
Query Neighborhood Hits	152	Target Neighborhood Hits	179	Shared Neighborhood Hits	11
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

CAC1G_HUMAN
NC score	0.011799 (rank : 185)	θ value	2.36792 (rank : 87)
Query Neighborhood Hits	152	Target Neighborhood Hits	587	Shared Neighborhood Hits	29
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

BRCA2_MOUSE
NC score	0.011797 (rank : 186)	θ value	5.27518 (rank : 117)
Query Neighborhood Hits	152	Target Neighborhood Hits	222	Shared Neighborhood Hits	14
SwissProt Accessions	P97929, O35922, P97383	Gene names	Brca2, Fancd1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein homolog (Fanconi anemia group D1 protein homolog).

MICA1_HUMAN
NC score	0.010751 (rank : 187)	θ value	1.81305 (rank : 83)
Query Neighborhood Hits	152	Target Neighborhood Hits	279	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TDZ2, Q7Z633, Q8IVS9, Q96G47, Q9H6X6, Q9H7I0, Q9HAA1, Q9UFF7	Gene names	MICAL1, MICAL, NICAL
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

CLSPN_MOUSE
NC score	0.010429 (rank : 188)	θ value	6.88961 (rank : 129)
Query Neighborhood Hits	152	Target Neighborhood Hits	292	Shared Neighborhood Hits	9
SwissProt Accessions	Q80YR7, Q69GM2	Gene names	Clspn
Domain Architecture	No domain graphic available
Description	Claspin.

TITIN_HUMAN
NC score	0.010425 (rank : 189)	θ value	5.27518 (rank : 126)
Query Neighborhood Hits	152	Target Neighborhood Hits	2923	Shared Neighborhood Hits	72
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

SPEG_MOUSE
NC score	0.010318 (rank : 190)	θ value	0.365318 (rank : 50)
Query Neighborhood Hits	152	Target Neighborhood Hits	1959	Shared Neighborhood Hits	67
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

VP13A_HUMAN
NC score	0.010079 (rank : 191)	θ value	6.88961 (rank : 139)
Query Neighborhood Hits	152	Target Neighborhood Hits	93	Shared Neighborhood Hits	4
SwissProt Accessions	Q96RL7, Q5JSX9, Q5JSY0, Q5VYR5, Q702P4, Q709D0, Q86YF8, Q96S61, Q9H995, Q9Y2J1	Gene names	VPS13A, CHAC, KIAA0986
Domain Architecture
Description	Vacuolar protein sorting-associated protein 13A (Chorein) (Chorea- acanthocytosis protein).

BCOR_HUMAN
NC score	0.009923 (rank : 192)	θ value	1.81305 (rank : 80)
Query Neighborhood Hits	152	Target Neighborhood Hits	609	Shared Neighborhood Hits	25
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

TCEA2_HUMAN
NC score	0.009880 (rank : 193)	θ value	4.03905 (rank : 114)
Query Neighborhood Hits	152	Target Neighborhood Hits	81	Shared Neighborhood Hits	5
SwissProt Accessions	Q15560, Q8TD37, Q8TD38	Gene names	TCEA2
Domain Architecture
Description	Transcription elongation factor A protein 2 (Transcription elongation factor S-II protein 2) (Testis-specific S-II) (Transcription elongation factor TFIIS.l).

PO6F1_MOUSE
NC score	0.009657 (rank : 194)	θ value	1.06291 (rank : 67)
Query Neighborhood Hits	152	Target Neighborhood Hits	581	Shared Neighborhood Hits	18
SwissProt Accessions	Q07916, Q91XK3	Gene names	Pou6f1, Emb
Domain Architecture
Description	POU domain, class 6, transcription factor 1 (Octamer-binding transcription factor EMB) (Transcription regulatory protein MCP-1).

NCOA7_MOUSE
NC score	0.009433 (rank : 195)	θ value	8.99809 (rank : 147)
Query Neighborhood Hits	152	Target Neighborhood Hits	114	Shared Neighborhood Hits	7
SwissProt Accessions	Q6DFV7, Q3TAR1, Q3UNB3, Q66K05, Q6ZQM4, Q8BJ15, Q8BJ39	Gene names	Ncoa7
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 7.

BRE1B_HUMAN
NC score	0.009430 (rank : 196)	θ value	1.38821 (rank : 71)
Query Neighborhood Hits	152	Target Neighborhood Hits	1040	Shared Neighborhood Hits	18
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

S3TC1_HUMAN
NC score	0.009145 (rank : 197)	θ value	6.88961 (rank : 135)
Query Neighborhood Hits	152	Target Neighborhood Hits	78	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TE82	Gene names	SH3TC1
Domain Architecture	No domain graphic available
Description	SH3 domain and tetratricopeptide repeats-containing protein 1.

NPHN_MOUSE
NC score	0.008307 (rank : 198)	θ value	3.0926 (rank : 103)
Query Neighborhood Hits	152	Target Neighborhood Hits	370	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QZS7	Gene names	Nphs1, Nphn
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

MEGF9_MOUSE
NC score	0.008190 (rank : 199)	θ value	5.27518 (rank : 121)
Query Neighborhood Hits	152	Target Neighborhood Hits	896	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

NPHN_HUMAN
NC score	0.007860 (rank : 200)	θ value	4.03905 (rank : 111)
Query Neighborhood Hits	152	Target Neighborhood Hits	362	Shared Neighborhood Hits	8
SwissProt Accessions	O60500	Gene names	NPHS1, NPHN
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

SPEG_HUMAN
NC score	0.007654 (rank : 201)	θ value	3.0926 (rank : 105)
Query Neighborhood Hits	152	Target Neighborhood Hits	1762	Shared Neighborhood Hits	61
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

BRE1B_MOUSE
NC score	0.006795 (rank : 202)	θ value	8.99809 (rank : 141)
Query Neighborhood Hits	152	Target Neighborhood Hits	970	Shared Neighborhood Hits	15
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

MAST4_HUMAN
NC score	0.006089 (rank : 203)	θ value	1.38821 (rank : 72)
Query Neighborhood Hits	152	Target Neighborhood Hits	1804	Shared Neighborhood Hits	63
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

RPGF1_HUMAN
NC score	0.005981 (rank : 204)	θ value	8.99809 (rank : 148)
Query Neighborhood Hits	152	Target Neighborhood Hits	262	Shared Neighborhood Hits	14
SwissProt Accessions	Q13905	Gene names	RAPGEF1, GRF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP).

B4GN4_MOUSE
NC score	0.005017 (rank : 205)	θ value	8.99809 (rank : 140)
Query Neighborhood Hits	152	Target Neighborhood Hits	129	Shared Neighborhood Hits	8
SwissProt Accessions	Q766D5, Q8CHV2	Gene names	B4galnt4
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 1 (EC 2.4.1.244) (NGalNAc-T1) (Beta- 1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4).

SC5A4_HUMAN
NC score	0.003122 (rank : 206)	θ value	8.99809 (rank : 149)
Query Neighborhood Hits	152	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NY91, O15279	Gene names	SLC5A4, SAAT1, SGLT2
Domain Architecture
Description	Low affinity sodium-glucose cotransporter (Sodium/glucose cotransporter 3) (Na(+)/glucose cotransporter 3).

RHG05_HUMAN
NC score	0.003023 (rank : 207)	θ value	6.88961 (rank : 134)
Query Neighborhood Hits	152	Target Neighborhood Hits	158	Shared Neighborhood Hits	2
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

AL1A3_HUMAN
NC score	0.002373 (rank : 208)	θ value	6.88961 (rank : 127)
Query Neighborhood Hits	152	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	P47895, Q6NT64	Gene names	ALDH1A3, ALDH6
Domain Architecture
Description	Aldehyde dehydrogenase 1A3 (EC 1.2.1.5) (Aldehyde dehydrogenase 6) (Retinaldehyde dehydrogenase 3) (RALDH-3).

DSCAM_HUMAN
NC score	0.002284 (rank : 209)	θ value	6.88961 (rank : 130)
Query Neighborhood Hits	152	Target Neighborhood Hits	524	Shared Neighborhood Hits	9
SwissProt Accessions	O60469, O60468	Gene names	DSCAM
Domain Architecture
Description	Down syndrome cell adhesion molecule precursor (CHD2).

BC11B_MOUSE
NC score	-0.000432 (rank : 210)	θ value	1.81305 (rank : 79)
Query Neighborhood Hits	152	Target Neighborhood Hits	767	Shared Neighborhood Hits	13
SwissProt Accessions	Q99PV8, Q8C2I1, Q99PV6, Q99PV7, Q9JLF8	Gene names	Bcl11b, Ctip2, Rit1
Domain Architecture	No domain graphic available
Description	B-cell lymphoma/leukemia 11B (B-cell CLL/lymphoma 11B) (Radiation- induced tumor suppressor gene 1 protein) (mRit1) (COUP-TF-interacting protein 2).

ZN509_MOUSE
NC score	-0.000932 (rank : 211)	θ value	2.36792 (rank : 96)
Query Neighborhood Hits	152	Target Neighborhood Hits	990	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BXX2, Q8CID4, Q8K2Z6	Gene names	Znf509, Zfp509
Domain Architecture	No domain graphic available
Description	Zinc finger protein 509.

EVI1_HUMAN
NC score	-0.002178 (rank : 212)	θ value	2.36792 (rank : 89)
Query Neighborhood Hits	152	Target Neighborhood Hits	924	Shared Neighborhood Hits	16
SwissProt Accessions	Q03112, Q16122, Q99917	Gene names	EVI1
Domain Architecture
Description	Ecotropic virus integration 1 site protein.

MELK_MOUSE
NC score	-0.002810 (rank : 213)	θ value	5.27518 (rank : 122)
Query Neighborhood Hits	152	Target Neighborhood Hits	860	Shared Neighborhood Hits	7
SwissProt Accessions	Q61846, Q61804, Q6ZQH6	Gene names	Melk, Kiaa0175, Pk38
Domain Architecture	No domain graphic available
Description	Maternal embryonic leucine zipper kinase (EC 2.7.11.1) (Protein kinase PK38) (mPK38).

NEK4_MOUSE
NC score	-0.002843 (rank : 214)	θ value	4.03905 (rank : 110)
Query Neighborhood Hits	152	Target Neighborhood Hits	899	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z1J2, O35673, Q9R1J1	Gene names	Nek4, Stk2
Domain Architecture
Description	Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2).

ZN398_HUMAN
NC score	-0.004037 (rank : 215)	θ value	8.99809 (rank : 152)
Query Neighborhood Hits	152	Target Neighborhood Hits	765	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TD17, Q8TD18, Q9P2K7, Q9UDV8	Gene names	ZNF398, KIAA1339, ZER6
Domain Architecture
Description	Zinc finger protein 398 (Zinc finger DNA-binding protein p52/p71).