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Network neighborhood for query Sequence : RHG05_HUMAN

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RHG05_HUMAN
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GRLF1_HUMAN
θ value	0 (rank : 1)	NC score	0.964174 (rank : 3)
Query Neighborhood Hits	158	Target Neighborhood Hits	167	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

RHG05_HUMAN
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	158	Target Neighborhood Hits	158	Shared Neighborhood Hits	158
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

RHG05_MOUSE
θ value	0 (rank : 3)	NC score	0.995040 (rank : 2)
Query Neighborhood Hits	158	Target Neighborhood Hits	165	Shared Neighborhood Hits	139
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

CHIN_HUMAN
θ value	2.05525e-28 (rank : 4)	NC score	0.712541 (rank : 17)
Query Neighborhood Hits	158	Target Neighborhood Hits	227	Shared Neighborhood Hits	61
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIN_MOUSE
θ value	3.50572e-28 (rank : 5)	NC score	0.714138 (rank : 16)
Query Neighborhood Hits	158	Target Neighborhood Hits	229	Shared Neighborhood Hits	62
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIO_MOUSE
θ value	3.28125e-26 (rank : 6)	NC score	0.742127 (rank : 7)
Query Neighborhood Hits	158	Target Neighborhood Hits	130	Shared Neighborhood Hits	61
SwissProt Accessions	Q80XD1, Q9D9W2, Q9ER57	Gene names	Chn2, Arhgap3, Bch
Domain Architecture	No domain graphic available
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

CHIO_HUMAN
θ value	2.12685e-25 (rank : 7)	NC score	0.710795 (rank : 18)
Query Neighborhood Hits	158	Target Neighborhood Hits	220	Shared Neighborhood Hits	61
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

ABR_HUMAN
θ value	2.06002e-20 (rank : 8)	NC score	0.684868 (rank : 23)
Query Neighborhood Hits	158	Target Neighborhood Hits	166	Shared Neighborhood Hits	62
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

BCR_HUMAN
θ value	2.06002e-20 (rank : 9)	NC score	0.672102 (rank : 30)
Query Neighborhood Hits	158	Target Neighborhood Hits	204	Shared Neighborhood Hits	62
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

OPHN1_MOUSE
θ value	1.74391e-19 (rank : 10)	NC score	0.725524 (rank : 13)
Query Neighborhood Hits	158	Target Neighborhood Hits	174	Shared Neighborhood Hits	69
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

RHG12_HUMAN
θ value	2.97466e-19 (rank : 11)	NC score	0.756801 (rank : 6)
Query Neighborhood Hits	158	Target Neighborhood Hits	190	Shared Neighborhood Hits	67
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RHG12_MOUSE
θ value	2.97466e-19 (rank : 12)	NC score	0.757905 (rank : 5)
Query Neighborhood Hits	158	Target Neighborhood Hits	204	Shared Neighborhood Hits	69
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

OPHN1_HUMAN
θ value	3.88503e-19 (rank : 13)	NC score	0.727278 (rank : 12)
Query Neighborhood Hits	158	Target Neighborhood Hits	161	Shared Neighborhood Hits	70
SwissProt Accessions	O60890, Q5JQ81, Q8WX47	Gene names	OPHN1
Domain Architecture
Description	Oligophrenin 1.

SRGP2_HUMAN
θ value	2.5182e-18 (rank : 14)	NC score	0.664917 (rank : 32)
Query Neighborhood Hits	158	Target Neighborhood Hits	331	Shared Neighborhood Hits	74
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

RHG04_HUMAN
θ value	9.56915e-18 (rank : 15)	NC score	0.673044 (rank : 29)
Query Neighborhood Hits	158	Target Neighborhood Hits	307	Shared Neighborhood Hits	69
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

SRGP2_MOUSE
θ value	9.56915e-18 (rank : 16)	NC score	0.658223 (rank : 34)
Query Neighborhood Hits	158	Target Neighborhood Hits	324	Shared Neighborhood Hits	75
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

3BP1_HUMAN
θ value	6.20254e-17 (rank : 17)	NC score	0.719086 (rank : 15)
Query Neighborhood Hits	158	Target Neighborhood Hits	376	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

CEND2_HUMAN
θ value	1.058e-16 (rank : 18)	NC score	0.611763 (rank : 42)
Query Neighborhood Hits	158	Target Neighborhood Hits	166	Shared Neighborhood Hits	60
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

RHG09_HUMAN
θ value	1.058e-16 (rank : 19)	NC score	0.774564 (rank : 4)
Query Neighborhood Hits	158	Target Neighborhood Hits	186	Shared Neighborhood Hits	64
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

MYO9B_HUMAN
θ value	1.38178e-16 (rank : 20)	NC score	0.391274 (rank : 58)
Query Neighborhood Hits	158	Target Neighborhood Hits	641	Shared Neighborhood Hits	74
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

MYO9B_MOUSE
θ value	1.80466e-16 (rank : 21)	NC score	0.396938 (rank : 57)
Query Neighborhood Hits	158	Target Neighborhood Hits	311	Shared Neighborhood Hits	74
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

SRGP1_HUMAN
θ value	3.07829e-16 (rank : 22)	NC score	0.653801 (rank : 36)
Query Neighborhood Hits	158	Target Neighborhood Hits	390	Shared Neighborhood Hits	82
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

RHG26_HUMAN
θ value	4.02038e-16 (rank : 23)	NC score	0.676217 (rank : 26)
Query Neighborhood Hits	158	Target Neighborhood Hits	281	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

RGAP1_HUMAN
θ value	5.25075e-16 (rank : 24)	NC score	0.741197 (rank : 8)
Query Neighborhood Hits	158	Target Neighborhood Hits	189	Shared Neighborhood Hits	73
SwissProt Accessions	Q9H0H5, Q6PJ26, Q9NWN2, Q9P250, Q9P2W2	Gene names	RACGAP1, KIAA1478, MGCRACGAP
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

CEND3_HUMAN
θ value	3.40345e-15 (rank : 25)	NC score	0.565391 (rank : 48)
Query Neighborhood Hits	158	Target Neighborhood Hits	275	Shared Neighborhood Hits	60
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

CEND3_MOUSE
θ value	3.40345e-15 (rank : 26)	NC score	0.576708 (rank : 47)
Query Neighborhood Hits	158	Target Neighborhood Hits	228	Shared Neighborhood Hits	61
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

FNBP2_HUMAN
θ value	4.44505e-15 (rank : 27)	NC score	0.648444 (rank : 38)
Query Neighborhood Hits	158	Target Neighborhood Hits	432	Shared Neighborhood Hits	78
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

RGAP1_MOUSE
θ value	1.68911e-14 (rank : 28)	NC score	0.736999 (rank : 9)
Query Neighborhood Hits	158	Target Neighborhood Hits	185	Shared Neighborhood Hits	66
SwissProt Accessions	Q9WVM1, Q3THR5, Q3TI41, Q3TM81	Gene names	Racgap1, Mgcracgap
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

CE005_MOUSE
θ value	2.20605e-14 (rank : 29)	NC score	0.603382 (rank : 45)
Query Neighborhood Hits	158	Target Neighborhood Hits	238	Shared Neighborhood Hits	76
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

RBP1_HUMAN
θ value	3.76295e-14 (rank : 30)	NC score	0.656637 (rank : 35)
Query Neighborhood Hits	158	Target Neighborhood Hits	521	Shared Neighborhood Hits	91
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

TCGAP_HUMAN
θ value	4.91457e-14 (rank : 31)	NC score	0.612141 (rank : 41)
Query Neighborhood Hits	158	Target Neighborhood Hits	872	Shared Neighborhood Hits	69
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TCGAP_MOUSE
θ value	4.91457e-14 (rank : 32)	NC score	0.689424 (rank : 22)
Query Neighborhood Hits	158	Target Neighborhood Hits	409	Shared Neighborhood Hits	66
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

CE005_HUMAN
θ value	8.38298e-14 (rank : 33)	NC score	0.604787 (rank : 44)
Query Neighborhood Hits	158	Target Neighborhood Hits	213	Shared Neighborhood Hits	76
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

RHG25_MOUSE
θ value	1.42992e-13 (rank : 34)	NC score	0.659236 (rank : 33)
Query Neighborhood Hits	158	Target Neighborhood Hits	492	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

CEND1_MOUSE
θ value	1.86753e-13 (rank : 35)	NC score	0.527823 (rank : 53)
Query Neighborhood Hits	158	Target Neighborhood Hits	260	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

GMIP_HUMAN
θ value	1.86753e-13 (rank : 36)	NC score	0.725443 (rank : 14)
Query Neighborhood Hits	158	Target Neighborhood Hits	225	Shared Neighborhood Hits	66
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

3BP1_MOUSE
θ value	2.43908e-13 (rank : 37)	NC score	0.727976 (rank : 11)
Query Neighborhood Hits	158	Target Neighborhood Hits	238	Shared Neighborhood Hits	65
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

GMIP_MOUSE
θ value	2.43908e-13 (rank : 38)	NC score	0.731869 (rank : 10)
Query Neighborhood Hits	158	Target Neighborhood Hits	202	Shared Neighborhood Hits	65
SwissProt Accessions	Q6PGG2, Q6P9S3	Gene names	Gmip
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

RHG01_HUMAN
θ value	7.09661e-13 (rank : 39)	NC score	0.703387 (rank : 19)
Query Neighborhood Hits	158	Target Neighborhood Hits	75	Shared Neighborhood Hits	62
SwissProt Accessions	Q07960	Gene names	ARHGAP1, CDC42GAP, RHOGAP1
Domain Architecture
Description	Rho-GTPase-activating protein 1 (GTPase-activating protein rhoOGAP) (Rho-related small GTPase protein activator) (CDC42 GTPase-activating protein) (p50-RhoGAP).

CEND1_HUMAN
θ value	9.26847e-13 (rank : 40)	NC score	0.506706 (rank : 54)
Query Neighborhood Hits	158	Target Neighborhood Hits	284	Shared Neighborhood Hits	56
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

RHG25_HUMAN
θ value	2.0648e-12 (rank : 41)	NC score	0.637753 (rank : 40)
Query Neighborhood Hits	158	Target Neighborhood Hits	550	Shared Neighborhood Hits	83
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RBP1_MOUSE
θ value	3.52202e-12 (rank : 42)	NC score	0.665459 (rank : 31)
Query Neighborhood Hits	158	Target Neighborhood Hits	493	Shared Neighborhood Hits	88
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

RHG08_HUMAN
θ value	1.33837e-11 (rank : 43)	NC score	0.680465 (rank : 25)
Query Neighborhood Hits	158	Target Neighborhood Hits	88	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NSG0, O75983, O95695, Q96RW1, Q96RW2, Q9HA49, Q9HC46, Q9NVX8, Q9NXL1, Q9UH20	Gene names	ARHGAP8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RHG08_MOUSE
θ value	1.47974e-10 (rank : 44)	NC score	0.680950 (rank : 24)
Query Neighborhood Hits	158	Target Neighborhood Hits	73	Shared Neighborhood Hits	62
SwissProt Accessions	Q9CXP4, Q99JY7	Gene names	Arhgap8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

TAGAP_HUMAN
θ value	3.29651e-10 (rank : 45)	NC score	0.651984 (rank : 37)
Query Neighborhood Hits	158	Target Neighborhood Hits	82	Shared Neighborhood Hits	62
SwissProt Accessions	Q8N103, Q2NKM8, Q8NI40, Q96KZ2, Q96QA2	Gene names	TAGAP, TAGAP1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

TCRG1_HUMAN
θ value	5.62301e-10 (rank : 46)	NC score	0.164713 (rank : 63)
Query Neighborhood Hits	158	Target Neighborhood Hits	929	Shared Neighborhood Hits	49
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TCRG1_MOUSE
θ value	5.62301e-10 (rank : 47)	NC score	0.164106 (rank : 64)
Query Neighborhood Hits	158	Target Neighborhood Hits	947	Shared Neighborhood Hits	51
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

RHG07_HUMAN
θ value	9.59137e-10 (rank : 48)	NC score	0.598652 (rank : 46)
Query Neighborhood Hits	158	Target Neighborhood Hits	108	Shared Neighborhood Hits	64
SwissProt Accessions	Q96QB1, O14868, O43199, Q9C0E0	Gene names	DLC1, ARHGAP7, KIAA1723, STARD12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein) (Dlc-1) (HP protein) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

RHG07_MOUSE
θ value	9.59137e-10 (rank : 49)	NC score	0.605662 (rank : 43)
Query Neighborhood Hits	158	Target Neighborhood Hits	103	Shared Neighborhood Hits	66
SwissProt Accessions	Q9R0Z9, Q8R541	Gene names	Dlc1, Arhgap7, Stard12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein homolog) (Dlc-1) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

RHG06_HUMAN
θ value	2.13673e-09 (rank : 50)	NC score	0.697146 (rank : 20)
Query Neighborhood Hits	158	Target Neighborhood Hits	114	Shared Neighborhood Hits	62
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RHG18_MOUSE
θ value	6.21693e-09 (rank : 51)	NC score	0.673764 (rank : 28)
Query Neighborhood Hits	158	Target Neighborhood Hits	110	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K0Q5, Q8BP03, Q8R196	Gene names	Arhgap18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18.

RHG06_MOUSE
θ value	8.11959e-09 (rank : 52)	NC score	0.692908 (rank : 21)
Query Neighborhood Hits	158	Target Neighborhood Hits	105	Shared Neighborhood Hits	62
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

STA13_HUMAN
θ value	1.06045e-08 (rank : 53)	NC score	0.563566 (rank : 49)
Query Neighborhood Hits	158	Target Neighborhood Hits	89	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y3M8, Q5HYH1, Q5TAE3, Q6UN61, Q86TP6, Q86WQ3, Q86XT1	Gene names	STARD13, DLC2, GT650
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13) (46H23.2) (Deleted in liver cancer protein 2) (Rho GTPase-activating protein).

P85A_MOUSE
θ value	4.0297e-08 (rank : 54)	NC score	0.376212 (rank : 60)
Query Neighborhood Hits	158	Target Neighborhood Hits	435	Shared Neighborhood Hits	72
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

RHG18_HUMAN
θ value	4.0297e-08 (rank : 55)	NC score	0.674161 (rank : 27)
Query Neighborhood Hits	158	Target Neighborhood Hits	90	Shared Neighborhood Hits	63
SwissProt Accessions	Q8N392, Q58EZ3, Q6P679, Q6PJD7, Q96S64	Gene names	ARHGAP18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18 (MacGAP).

TAGAP_MOUSE
θ value	5.26297e-08 (rank : 56)	NC score	0.639735 (rank : 39)
Query Neighborhood Hits	158	Target Neighborhood Hits	83	Shared Neighborhood Hits	60
SwissProt Accessions	Q8K2L9, Q920D6	Gene names	Tagap, Tagap1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

P85A_HUMAN
θ value	8.97725e-08 (rank : 57)	NC score	0.379721 (rank : 59)
Query Neighborhood Hits	158	Target Neighborhood Hits	479	Shared Neighborhood Hits	77
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

STA13_MOUSE
θ value	1.17247e-07 (rank : 58)	NC score	0.552038 (rank : 52)
Query Neighborhood Hits	158	Target Neighborhood Hits	89	Shared Neighborhood Hits	58
SwissProt Accessions	Q923Q2, Q8K369	Gene names	Stard13
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13).

STAR8_HUMAN
θ value	1.29631e-06 (rank : 59)	NC score	0.552230 (rank : 51)
Query Neighborhood Hits	158	Target Neighborhood Hits	216	Shared Neighborhood Hits	59
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

STAR8_MOUSE
θ value	8.40245e-06 (rank : 60)	NC score	0.556635 (rank : 50)
Query Neighborhood Hits	158	Target Neighborhood Hits	101	Shared Neighborhood Hits	59
SwissProt Accessions	Q8K031, Q3UZC7, Q6A0A8, Q6P5E0, Q8R3X8	Gene names	Stard8, Kiaa0189
Domain Architecture	No domain graphic available
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

CTRO_MOUSE
θ value	4.1701e-05 (rank : 61)	NC score	0.032024 (rank : 133)
Query Neighborhood Hits	158	Target Neighborhood Hits	2344	Shared Neighborhood Hits	63
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

OCRL_HUMAN
θ value	0.000786445 (rank : 62)	NC score	0.304501 (rank : 62)
Query Neighborhood Hits	158	Target Neighborhood Hits	77	Shared Neighborhood Hits	51
SwissProt Accessions	Q01968, O60800, Q15684, Q15774, Q5JQF1, Q5JQF2, Q9UJG5, Q9UMA5	Gene names	OCRL, INPP5F, OCRL1
Domain Architecture
Description	Inositol polyphosphate 5-phosphatase OCRL-1 (EC 3.1.3.36) (Lowe oculocerebrorenal syndrome protein).

I5P2_HUMAN
θ value	0.00665767 (rank : 63)	NC score	0.312426 (rank : 61)
Query Neighborhood Hits	158	Target Neighborhood Hits	86	Shared Neighborhood Hits	52
SwissProt Accessions	P32019, Q5VSG9, Q5VSH0, Q5VSH1, Q658Q5, Q6P6D4, Q6PD53, Q86YE1	Gene names	INPP5B
Domain Architecture	No domain graphic available
Description	Type II inositol-1,4,5-trisphosphate 5-phosphatase precursor (EC 3.1.3.36) (Phosphoinositide 5-phosphatase) (5PTase) (75 kDa inositol polyphosphate-5-phosphatase).

STK10_HUMAN
θ value	0.00869519 (rank : 64)	NC score	0.014110 (rank : 164)
Query Neighborhood Hits	158	Target Neighborhood Hits	1921	Shared Neighborhood Hits	52
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

PRP40_HUMAN
θ value	0.0148317 (rank : 65)	NC score	0.109320 (rank : 66)
Query Neighborhood Hits	158	Target Neighborhood Hits	442	Shared Neighborhood Hits	25
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

PRP40_MOUSE
θ value	0.0148317 (rank : 66)	NC score	0.115148 (rank : 65)
Query Neighborhood Hits	158	Target Neighborhood Hits	447	Shared Neighborhood Hits	29
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

SYNE1_HUMAN
θ value	0.0193708 (rank : 67)	NC score	0.043185 (rank : 121)
Query Neighborhood Hits	158	Target Neighborhood Hits	1484	Shared Neighborhood Hits	60
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

CENPF_HUMAN
θ value	0.0736092 (rank : 68)	NC score	0.047260 (rank : 116)
Query Neighborhood Hits	158	Target Neighborhood Hits	1932	Shared Neighborhood Hits	70
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

MORC4_HUMAN
θ value	0.0736092 (rank : 69)	NC score	0.048074 (rank : 114)
Query Neighborhood Hits	158	Target Neighborhood Hits	244	Shared Neighborhood Hits	23
SwissProt Accessions	Q8TE76, Q5JUK7, Q96MZ2, Q9HAI7	Gene names	MORC4, ZCWCC2
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 4 (Zinc finger CW-type coiled- coil domain protein 2).

NIN_HUMAN
θ value	0.125558 (rank : 70)	NC score	0.051253 (rank : 106)
Query Neighborhood Hits	158	Target Neighborhood Hits	1416	Shared Neighborhood Hits	64
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

RAD50_MOUSE
θ value	0.125558 (rank : 71)	NC score	0.045534 (rank : 117)
Query Neighborhood Hits	158	Target Neighborhood Hits	1366	Shared Neighborhood Hits	54
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

COG8_HUMAN
θ value	0.21417 (rank : 72)	NC score	0.055133 (rank : 83)
Query Neighborhood Hits	158	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q96MW5, Q8WVV6, Q9H6F8	Gene names	COG8
Domain Architecture
Description	Conserved oligomeric Golgi complex component 8.

TRIPB_HUMAN
θ value	0.21417 (rank : 73)	NC score	0.042010 (rank : 124)
Query Neighborhood Hits	158	Target Neighborhood Hits	1587	Shared Neighborhood Hits	61
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

KTN1_HUMAN
θ value	0.365318 (rank : 74)	NC score	0.042066 (rank : 123)
Query Neighborhood Hits	158	Target Neighborhood Hits	1197	Shared Neighborhood Hits	51
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

RAD50_HUMAN
θ value	0.365318 (rank : 75)	NC score	0.044080 (rank : 119)
Query Neighborhood Hits	158	Target Neighborhood Hits	1317	Shared Neighborhood Hits	52
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

MYH1_MOUSE
θ value	0.47712 (rank : 76)	NC score	0.051953 (rank : 99)
Query Neighborhood Hits	158	Target Neighborhood Hits	1461	Shared Neighborhood Hits	68
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

PAWR_HUMAN
θ value	0.47712 (rank : 77)	NC score	0.059676 (rank : 78)
Query Neighborhood Hits	158	Target Neighborhood Hits	252	Shared Neighborhood Hits	17
SwissProt Accessions	Q96IZ0, O75796, Q6FHY9, Q8N700	Gene names	PAWR, PAR4
Domain Architecture	No domain graphic available
Description	PRKC apoptosis WT1 regulator protein (Prostate apoptosis response 4 protein) (Par-4).

SCYL2_HUMAN
θ value	0.47712 (rank : 78)	NC score	0.021553 (rank : 151)
Query Neighborhood Hits	158	Target Neighborhood Hits	632	Shared Neighborhood Hits	11
SwissProt Accessions	Q6P3W7, Q96EF4, Q96ST4, Q9H7V5, Q9NVH3, Q9P2I7	Gene names	SCYL2, CVAK104, KIAA1360
Domain Architecture	No domain graphic available
Description	SCY1-like protein 2 (Coated vesicle-associated kinase of 104 kDa).

BMR1B_HUMAN
θ value	0.62314 (rank : 79)	NC score	0.009095 (rank : 177)
Query Neighborhood Hits	158	Target Neighborhood Hits	760	Shared Neighborhood Hits	9
SwissProt Accessions	O00238, P78366	Gene names	BMPR1B
Domain Architecture
Description	Bone morphogenetic protein receptor type IB precursor (EC 2.7.11.30) (CDw293 antigen).

BMR1B_MOUSE
θ value	0.62314 (rank : 80)	NC score	0.008957 (rank : 179)
Query Neighborhood Hits	158	Target Neighborhood Hits	758	Shared Neighborhood Hits	9
SwissProt Accessions	P36898, Q3TRF2	Gene names	Bmpr1b, Acvrlk6
Domain Architecture
Description	Bone morphogenetic protein receptor type IB precursor (EC 2.7.11.30) (Serine/threonine-protein kinase receptor R6) (SKR6) (Activin receptor-like kinase 6) (ALK-6).

CTRO_HUMAN
θ value	0.62314 (rank : 81)	NC score	0.022782 (rank : 147)
Query Neighborhood Hits	158	Target Neighborhood Hits	2092	Shared Neighborhood Hits	60
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

IF3A_HUMAN
θ value	0.62314 (rank : 82)	NC score	0.055275 (rank : 82)
Query Neighborhood Hits	158	Target Neighborhood Hits	875	Shared Neighborhood Hits	46
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

MYH2_HUMAN
θ value	0.62314 (rank : 83)	NC score	0.049614 (rank : 112)
Query Neighborhood Hits	158	Target Neighborhood Hits	1491	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

RAB4B_HUMAN
θ value	0.62314 (rank : 84)	NC score	0.017183 (rank : 156)
Query Neighborhood Hits	158	Target Neighborhood Hits	283	Shared Neighborhood Hits	13
SwissProt Accessions	P61018, P22750, Q7Z514, Q9HBR6	Gene names	RAB4B
Domain Architecture
Description	Ras-related protein Rab-4B.

RAB4B_MOUSE
θ value	0.62314 (rank : 85)	NC score	0.017185 (rank : 155)
Query Neighborhood Hits	158	Target Neighborhood Hits	283	Shared Neighborhood Hits	13
SwissProt Accessions	Q91ZR1	Gene names	Rab4b, Rab4
Domain Architecture
Description	Ras-related protein Rab-4B.

SCYL2_MOUSE
θ value	0.62314 (rank : 86)	NC score	0.023069 (rank : 145)
Query Neighborhood Hits	158	Target Neighborhood Hits	603	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CFE4, Q3UT57, Q3UWU9, Q8K0M4	Gene names	Scyl2, Cvak104, D10Ertd802e
Domain Architecture	No domain graphic available
Description	SCY1-like protein 2 (Coated vesicle-associated kinase of 104 kDa).

SLK_MOUSE
θ value	0.62314 (rank : 87)	NC score	0.012118 (rank : 171)
Query Neighborhood Hits	158	Target Neighborhood Hits	1798	Shared Neighborhood Hits	53
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

GOGB1_HUMAN
θ value	0.813845 (rank : 88)	NC score	0.043642 (rank : 120)
Query Neighborhood Hits	158	Target Neighborhood Hits	2297	Shared Neighborhood Hits	73
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

K1688_MOUSE
θ value	0.813845 (rank : 89)	NC score	0.431187 (rank : 55)
Query Neighborhood Hits	158	Target Neighborhood Hits	188	Shared Neighborhood Hits	63
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

KI13A_HUMAN
θ value	0.813845 (rank : 90)	NC score	0.012348 (rank : 168)
Query Neighborhood Hits	158	Target Neighborhood Hits	359	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H1H9, Q9H1H8	Gene names	KIF13A, RBKIN
Domain Architecture
Description	Kinesin-like protein KIF13A (Kinesin-like protein RBKIN).

RAB4A_HUMAN
θ value	0.813845 (rank : 91)	NC score	0.015418 (rank : 159)
Query Neighborhood Hits	158	Target Neighborhood Hits	275	Shared Neighborhood Hits	12
SwissProt Accessions	P20338, Q9BQ44	Gene names	RAB4A, RAB4
Domain Architecture
Description	Ras-related protein Rab-4A.

TACC3_MOUSE
θ value	0.813845 (rank : 92)	NC score	0.038915 (rank : 127)
Query Neighborhood Hits	158	Target Neighborhood Hits	607	Shared Neighborhood Hits	39
SwissProt Accessions	Q9JJ11, Q9WVK9	Gene names	Tacc3, Aint
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ARNT-interacting protein).

LAMA3_HUMAN
θ value	1.06291 (rank : 93)	NC score	0.022871 (rank : 146)
Query Neighborhood Hits	158	Target Neighborhood Hits	760	Shared Neighborhood Hits	32
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

MYH8_HUMAN
θ value	1.06291 (rank : 94)	NC score	0.053344 (rank : 90)
Query Neighborhood Hits	158	Target Neighborhood Hits	1610	Shared Neighborhood Hits	65
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

SLK_HUMAN
θ value	1.06291 (rank : 95)	NC score	0.011186 (rank : 173)
Query Neighborhood Hits	158	Target Neighborhood Hits	1775	Shared Neighborhood Hits	53
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

SPTA1_HUMAN
θ value	1.06291 (rank : 96)	NC score	0.050326 (rank : 110)
Query Neighborhood Hits	158	Target Neighborhood Hits	748	Shared Neighborhood Hits	49
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

IF3A_MOUSE
θ value	1.38821 (rank : 97)	NC score	0.053257 (rank : 91)
Query Neighborhood Hits	158	Target Neighborhood Hits	871	Shared Neighborhood Hits	48
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

RAB4A_MOUSE
θ value	1.38821 (rank : 98)	NC score	0.014455 (rank : 163)
Query Neighborhood Hits	158	Target Neighborhood Hits	271	Shared Neighborhood Hits	12
SwissProt Accessions	P56371	Gene names	Rab4a, Rab4
Domain Architecture
Description	Ras-related protein Rab-4A.

AASS_HUMAN
θ value	1.81305 (rank : 99)	NC score	0.026186 (rank : 139)
Query Neighborhood Hits	158	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UDR5, O95462	Gene names	AASS
Domain Architecture
Description	Alpha-aminoadipic semialdehyde synthase, mitochondrial precursor (LKR/SDH) [Includes: Lysine ketoglutarate reductase (EC 1.5.1.8) (LOR) (LKR); Saccharopine dehydrogenase (EC 1.5.1.9) (SDH)].

CCD11_HUMAN
θ value	1.81305 (rank : 100)	NC score	0.042978 (rank : 122)
Query Neighborhood Hits	158	Target Neighborhood Hits	822	Shared Neighborhood Hits	43
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

COVA1_HUMAN
θ value	1.81305 (rank : 101)	NC score	0.023562 (rank : 144)
Query Neighborhood Hits	158	Target Neighborhood Hits	416	Shared Neighborhood Hits	21
SwissProt Accessions	Q16206, Q5VTJ1, Q5VTJ2, Q8WUX0, Q9NTP6, Q9UH82	Gene names	COVA1
Domain Architecture
Description	Tumor-associated hydroquinone oxidase (tNOX) (Cytosolic ovarian carcinoma antigen 1) (APK1 antigen) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)].

G45IP_HUMAN
θ value	1.81305 (rank : 102)	NC score	0.035465 (rank : 128)
Query Neighborhood Hits	158	Target Neighborhood Hits	118	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TAE8, Q8IVM3, Q8TE51, Q969P9, Q9BSM6	Gene names	GADD45GIP1, PLINP1
Domain Architecture	No domain graphic available
Description	Growth arrest and DNA-damage-inducible proteins-interacting protein 1 (CR6-interacting factor 1) (CRIF1) (CKII beta-associating protein) (Papillomavirus L2-interacting nuclear protein 1) (PLINP-1).

MYH4_HUMAN
θ value	1.81305 (rank : 103)	NC score	0.051527 (rank : 102)
Query Neighborhood Hits	158	Target Neighborhood Hits	1377	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

RAB2B_HUMAN
θ value	1.81305 (rank : 104)	NC score	0.012183 (rank : 170)
Query Neighborhood Hits	158	Target Neighborhood Hits	271	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WUD1	Gene names	RAB2B
Domain Architecture
Description	Ras-related protein Rab-2B.

RAB2B_MOUSE
θ value	1.81305 (rank : 105)	NC score	0.012264 (rank : 169)
Query Neighborhood Hits	158	Target Neighborhood Hits	271	Shared Neighborhood Hits	12
SwissProt Accessions	P59279, Q3TV67	Gene names	Rab2b
Domain Architecture
Description	Ras-related protein Rab-2B.

SPTA1_MOUSE
θ value	1.81305 (rank : 106)	NC score	0.048221 (rank : 113)
Query Neighborhood Hits	158	Target Neighborhood Hits	675	Shared Neighborhood Hits	46
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

CA065_HUMAN
θ value	2.36792 (rank : 107)	NC score	0.041868 (rank : 125)
Query Neighborhood Hits	158	Target Neighborhood Hits	469	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N715, Q8N746, Q8NA93	Gene names	C1orf65
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf65.

DTBP1_HUMAN
θ value	2.36792 (rank : 108)	NC score	0.024877 (rank : 142)
Query Neighborhood Hits	158	Target Neighborhood Hits	185	Shared Neighborhood Hits	22
SwissProt Accessions	Q96EV8, Q96NV2, Q9H0U2, Q9H3J5	Gene names	DTNBP1
Domain Architecture
Description	Dystrobrevin-binding protein 1 (Dysbindin) (Hermansky-Pudlak syndrome 7 protein).

MYH8_MOUSE
θ value	2.36792 (rank : 109)	NC score	0.050930 (rank : 108)
Query Neighborhood Hits	158	Target Neighborhood Hits	1600	Shared Neighborhood Hits	63
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

TXLNA_MOUSE
θ value	2.36792 (rank : 110)	NC score	0.033999 (rank : 129)
Query Neighborhood Hits	158	Target Neighborhood Hits	846	Shared Neighborhood Hits	40
SwissProt Accessions	Q6PAM1, Q6P1E5	Gene names	Txlna, Txln
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

ES8L3_HUMAN
θ value	3.0926 (rank : 111)	NC score	0.008897 (rank : 180)
Query Neighborhood Hits	158	Target Neighborhood Hits	206	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TE67, Q5T8Q6, Q5T8Q7, Q5T8Q8, Q96E47, Q9H719	Gene names	EPS8L3, EPS8R3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

FAF1_MOUSE
θ value	3.0926 (rank : 112)	NC score	0.032822 (rank : 132)
Query Neighborhood Hits	158	Target Neighborhood Hits	107	Shared Neighborhood Hits	17
SwissProt Accessions	P54731	Gene names	Faf1
Domain Architecture
Description	FAS-associated factor 1 (Protein FAF1).

K0423_HUMAN
θ value	3.0926 (rank : 113)	NC score	0.027845 (rank : 138)
Query Neighborhood Hits	158	Target Neighborhood Hits	171	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y4F4, Q68D66, Q6PG27	Gene names	KIAA0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

K0423_MOUSE
θ value	3.0926 (rank : 114)	NC score	0.025085 (rank : 141)
Query Neighborhood Hits	158	Target Neighborhood Hits	115	Shared Neighborhood Hits	6
SwissProt Accessions	Q6A070	Gene names	Kiaa0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

MORC4_MOUSE
θ value	3.0926 (rank : 115)	NC score	0.028820 (rank : 136)
Query Neighborhood Hits	158	Target Neighborhood Hits	235	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BMD7, Q4KMM6, Q8BX95, Q9CS96	Gene names	Morc4, Zcwcc2
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 4 (Zinc finger CW-type coiled- coil domain protein 2).

MYH1_HUMAN
θ value	3.0926 (rank : 116)	NC score	0.049937 (rank : 111)
Query Neighborhood Hits	158	Target Neighborhood Hits	1478	Shared Neighborhood Hits	63
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

SIN3A_MOUSE
θ value	3.0926 (rank : 117)	NC score	0.024305 (rank : 143)
Query Neighborhood Hits	158	Target Neighborhood Hits	169	Shared Neighborhood Hits	11
SwissProt Accessions	Q60520, Q60820, Q62139, Q62140, Q7TPU8, Q7TSZ2	Gene names	Sin3a
Domain Architecture
Description	Paired amphipathic helix protein Sin3a (Transcriptional corepressor Sin3a) (Histone deacetylase complex subunit Sin3a).

TXLNA_HUMAN
θ value	3.0926 (rank : 118)	NC score	0.032989 (rank : 131)
Query Neighborhood Hits	158	Target Neighborhood Hits	982	Shared Neighborhood Hits	43
SwissProt Accessions	P40222, Q66K62, Q86T54, Q86T85, Q86T86, Q86Y86, Q86YW3, Q8N2Y3	Gene names	TXLNA, TXLN
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

CI093_HUMAN
θ value	4.03905 (rank : 119)	NC score	0.045310 (rank : 118)
Query Neighborhood Hits	158	Target Neighborhood Hits	1088	Shared Neighborhood Hits	57
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

K1688_HUMAN
θ value	4.03905 (rank : 120)	NC score	0.419454 (rank : 56)
Query Neighborhood Hits	158	Target Neighborhood Hits	217	Shared Neighborhood Hits	63
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

PIGN_HUMAN
θ value	4.03905 (rank : 121)	NC score	0.022524 (rank : 148)
Query Neighborhood Hits	158	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	O95427, Q7L8F8, Q8TC01, Q9NT05	Gene names	PIGN, MCD4
Domain Architecture	No domain graphic available
Description	GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class N protein) (PIG-N) (MCD4 homolog).

PROX1_MOUSE
θ value	4.03905 (rank : 122)	NC score	0.020418 (rank : 152)
Query Neighborhood Hits	158	Target Neighborhood Hits	184	Shared Neighborhood Hits	11
SwissProt Accessions	P48437, O88478, Q3UPV1, Q543D8	Gene names	Prox1
Domain Architecture
Description	Homeobox prospero-like protein PROX1 (PROX 1).

SEN54_MOUSE
θ value	4.03905 (rank : 123)	NC score	0.022512 (rank : 149)
Query Neighborhood Hits	158	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C2A2, Q9DCI5	Gene names	Tsen54, Sen54
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen54 (tRNA-intron endonuclease Sen54).

WDR67_HUMAN
θ value	4.03905 (rank : 124)	NC score	0.025209 (rank : 140)
Query Neighborhood Hits	158	Target Neighborhood Hits	782	Shared Neighborhood Hits	39
SwissProt Accessions	Q96DN5, Q3MIR6, Q8TBP9	Gene names	WDR67
Domain Architecture	No domain graphic available
Description	WD repeat protein 67.

ETV1_HUMAN
θ value	5.27518 (rank : 125)	NC score	0.008875 (rank : 181)
Query Neighborhood Hits	158	Target Neighborhood Hits	107	Shared Neighborhood Hits	4
SwissProt Accessions	P50549, O75849, Q9UQ71, Q9Y636	Gene names	ETV1, ER81
Domain Architecture
Description	ETS translocation variant 1 (ER81 protein).

FA48A_HUMAN
θ value	5.27518 (rank : 126)	NC score	0.011504 (rank : 172)
Query Neighborhood Hits	158	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NEM7, Q71RF3, Q9Y6A6	Gene names	FAM48A
Domain Architecture	No domain graphic available
Description	Protein FAM48A (p38-interacting protein) (p38IP).

FAF1_HUMAN
θ value	5.27518 (rank : 127)	NC score	0.029416 (rank : 135)
Query Neighborhood Hits	158	Target Neighborhood Hits	105	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UNN5, Q9UF34, Q9UNT3, Q9Y2Z3	Gene names	FAF1
Domain Architecture
Description	FAS-associated factor 1 (Protein FAF1) (hFAF1).

K2C4_HUMAN
θ value	5.27518 (rank : 128)	NC score	0.009620 (rank : 176)
Query Neighborhood Hits	158	Target Neighborhood Hits	471	Shared Neighborhood Hits	31
SwissProt Accessions	P19013, Q6GTR8, Q96LA7, Q9BTL1	Gene names	KRT4, CYK4
Domain Architecture
Description	Keratin, type II cytoskeletal 4 (Cytokeratin-4) (CK-4) (Keratin-4) (K4).

MYCN_HUMAN
θ value	5.27518 (rank : 129)	NC score	0.015626 (rank : 158)
Query Neighborhood Hits	158	Target Neighborhood Hits	127	Shared Neighborhood Hits	5
SwissProt Accessions	P04198, Q6LDT9	Gene names	MYCN, NMYC
Domain Architecture
Description	N-myc proto-oncogene protein.

MYCN_MOUSE
θ value	5.27518 (rank : 130)	NC score	0.015825 (rank : 157)
Query Neighborhood Hits	158	Target Neighborhood Hits	125	Shared Neighborhood Hits	5
SwissProt Accessions	P03966, Q61978	Gene names	Mycn, Nmyc, Nmyc1
Domain Architecture
Description	N-myc proto-oncogene protein.

PLXB1_HUMAN
θ value	5.27518 (rank : 131)	NC score	0.005742 (rank : 188)
Query Neighborhood Hits	158	Target Neighborhood Hits	360	Shared Neighborhood Hits	7
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

POLI_HUMAN
θ value	5.27518 (rank : 132)	NC score	0.009075 (rank : 178)
Query Neighborhood Hits	158	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UNA4, Q8N590, Q9H0S1, Q9NYH6	Gene names	POLI, RAD30B
Domain Architecture	No domain graphic available
Description	DNA polymerase iota (EC 2.7.7.7) (RAD30 homolog B) (Eta2).

SIN3A_HUMAN
θ value	5.27518 (rank : 133)	NC score	0.022258 (rank : 150)
Query Neighborhood Hits	158	Target Neighborhood Hits	180	Shared Neighborhood Hits	10
SwissProt Accessions	Q96ST3, Q8N8N4, Q8NC83, Q8WV18, Q96L98, Q9UFQ1	Gene names	SIN3A
Domain Architecture
Description	Paired amphipathic helix protein Sin3a (Transcriptional corepressor Sin3a) (Histone deacetylase complex subunit Sin3a).

TTLL2_HUMAN
θ value	5.27518 (rank : 134)	NC score	0.012635 (rank : 167)
Query Neighborhood Hits	158	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BWV7, Q7Z6R8, Q86X22	Gene names	TTLL2, C6orf104
Domain Architecture
Description	Tubulin--tyrosine ligase-like protein 2 (Testis-specific protein NYD- TSPG).

CE110_HUMAN
θ value	6.88961 (rank : 135)	NC score	0.013091 (rank : 165)
Query Neighborhood Hits	158	Target Neighborhood Hits	197	Shared Neighborhood Hits	19
SwissProt Accessions	O43303, O43335, Q68DV9, Q8NE13	Gene names	CEP110, CP110, KIAA0419
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 110 kDa (Cep110 protein).

ETV1_MOUSE
θ value	6.88961 (rank : 136)	NC score	0.007942 (rank : 187)
Query Neighborhood Hits	158	Target Neighborhood Hits	92	Shared Neighborhood Hits	4
SwissProt Accessions	P41164	Gene names	Etv1, Er81, Etsrp81
Domain Architecture
Description	ETS translocation variant 1 (ER81 protein).

EXOC6_HUMAN
θ value	6.88961 (rank : 137)	NC score	0.011046 (rank : 174)
Query Neighborhood Hits	158	Target Neighborhood Hits	57	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TAG9, Q9NZ24	Gene names	EXOC6, SEC15A, SEC15L, SEC15L1
Domain Architecture
Description	Exocyst complex component 6 (Exocyst complex component Sec15A) (Sec15- like 1).

JHD3B_MOUSE
θ value	6.88961 (rank : 138)	NC score	0.003023 (rank : 189)
Query Neighborhood Hits	158	Target Neighborhood Hits	152	Shared Neighborhood Hits	2
SwissProt Accessions	Q91VY5, Q3UR22, Q6ZQ30, Q99K42	Gene names	Jmjd2b, Jhdm3b
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

LMNB2_MOUSE
θ value	6.88961 (rank : 139)	NC score	0.012644 (rank : 166)
Query Neighborhood Hits	158	Target Neighborhood Hits	674	Shared Neighborhood Hits	29
SwissProt Accessions	P21619, P48680, Q8CGB1	Gene names	Lmnb2
Domain Architecture
Description	Lamin-B2.

PIGN_MOUSE
θ value	6.88961 (rank : 140)	NC score	0.019556 (rank : 153)
Query Neighborhood Hits	158	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q9R1S3, Q3V0S6, Q8VCC3, Q9R1S1, Q9R1S2	Gene names	Pign
Domain Architecture	No domain graphic available
Description	GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class N protein) (PIG-N).

PTPRZ_HUMAN
θ value	6.88961 (rank : 141)	NC score	0.000700 (rank : 191)
Query Neighborhood Hits	158	Target Neighborhood Hits	255	Shared Neighborhood Hits	3
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

RAB1A_HUMAN
θ value	6.88961 (rank : 142)	NC score	0.008105 (rank : 184)
Query Neighborhood Hits	158	Target Neighborhood Hits	292	Shared Neighborhood Hits	12
SwissProt Accessions	P62820, P11476, Q96N61, Q9Y3T2	Gene names	RAB1A, RAB1
Domain Architecture	No domain graphic available
Description	Ras-related protein Rab-1A (YPT1-related protein).

RAB1A_MOUSE
θ value	6.88961 (rank : 143)	NC score	0.008105 (rank : 185)
Query Neighborhood Hits	158	Target Neighborhood Hits	292	Shared Neighborhood Hits	12
SwissProt Accessions	P62821, P11476, Q3TX44, Q811M4, Q96N61, Q9Y3T2	Gene names	Rab1A, Rab1
Domain Architecture	No domain graphic available
Description	Ras-related protein Rab-1A (YPT1-related protein).

RAB1B_HUMAN
θ value	6.88961 (rank : 144)	NC score	0.008111 (rank : 183)
Query Neighborhood Hits	158	Target Neighborhood Hits	295	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H0U4	Gene names	RAB1B
Domain Architecture
Description	Ras-related protein Rab-1B.

RAB1B_MOUSE
θ value	6.88961 (rank : 145)	NC score	0.008096 (rank : 186)
Query Neighborhood Hits	158	Target Neighborhood Hits	296	Shared Neighborhood Hits	12
SwissProt Accessions	Q9D1G1, Q3U0N1	Gene names	Rab1b
Domain Architecture
Description	Ras-related protein Rab-1B.

1433Z_MOUSE
θ value	8.99809 (rank : 146)	NC score	0.002814 (rank : 190)
Query Neighborhood Hits	158	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	P63101, P35215, P70197, P97286, Q3TSF1, Q5EBQ1	Gene names	Ywhaz
Domain Architecture	No domain graphic available
Description	14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1) (SEZ-2).

AN30A_HUMAN
θ value	8.99809 (rank : 147)	NC score	0.017745 (rank : 154)
Query Neighborhood Hits	158	Target Neighborhood Hits	1119	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

BCAR1_MOUSE
θ value	8.99809 (rank : 148)	NC score	0.030761 (rank : 134)
Query Neighborhood Hits	158	Target Neighborhood Hits	438	Shared Neighborhood Hits	18
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

CA048_HUMAN
θ value	8.99809 (rank : 149)	NC score	0.015145 (rank : 161)
Query Neighborhood Hits	158	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q96IY1, Q5SY75, Q9H2M5, Q9NRN8, Q9Y415	Gene names	C1orf48
Domain Architecture	No domain graphic available
Description	Protein C1orf48.

CCD46_HUMAN
θ value	8.99809 (rank : 150)	NC score	0.041866 (rank : 126)
Query Neighborhood Hits	158	Target Neighborhood Hits	1430	Shared Neighborhood Hits	67
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

COG8_MOUSE
θ value	8.99809 (rank : 151)	NC score	0.033660 (rank : 130)
Query Neighborhood Hits	158	Target Neighborhood Hits	147	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JJA2	Gene names	Cog8
Domain Architecture
Description	Conserved oligomeric Golgi complex component 8.

CYLN2_HUMAN
θ value	8.99809 (rank : 152)	NC score	0.028697 (rank : 137)
Query Neighborhood Hits	158	Target Neighborhood Hits	1004	Shared Neighborhood Hits	48
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

GHR_MOUSE
θ value	8.99809 (rank : 153)	NC score	0.010574 (rank : 175)
Query Neighborhood Hits	158	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	P16882, P16590, Q61653, Q6DI66, Q80W86, Q8R1M5, Q920Z3, Q9R264	Gene names	Ghr
Domain Architecture
Description	Growth hormone receptor precursor (GH receptor) (Somatotropin receptor) [Contains: Growth hormone-binding protein (GH-binding protein) (GHBP) (Serum-binding protein)].

MYH4_MOUSE
θ value	8.99809 (rank : 154)	NC score	0.047839 (rank : 115)
Query Neighborhood Hits	158	Target Neighborhood Hits	1476	Shared Neighborhood Hits	65
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

NOG1_HUMAN
θ value	8.99809 (rank : 155)	NC score	0.008393 (rank : 182)
Query Neighborhood Hits	158	Target Neighborhood Hits	98	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BZE4, O95446, Q9NVJ8	Gene names	GTPBP4, CRFG, NOG1
Domain Architecture
Description	Nucleolar GTP-binding protein 1 (Chronic renal failure gene protein) (GTP-binding protein NGB).

NUCB1_HUMAN
θ value	8.99809 (rank : 156)	NC score	0.014921 (rank : 162)
Query Neighborhood Hits	158	Target Neighborhood Hits	359	Shared Neighborhood Hits	24
SwissProt Accessions	Q02818, Q15838, Q7Z4J7, Q9BUR1	Gene names	NUCB1, NUC
Domain Architecture	No domain graphic available
Description	Nucleobindin-1 precursor (CALNUC).

SSPO_MOUSE
θ value	8.99809 (rank : 157)	NC score	-0.000884 (rank : 192)
Query Neighborhood Hits	158	Target Neighborhood Hits	800	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

YLPM1_HUMAN
θ value	8.99809 (rank : 158)	NC score	0.015324 (rank : 160)
Query Neighborhood Hits	158	Target Neighborhood Hits	670	Shared Neighborhood Hits	11
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

CENA1_HUMAN
θ value	θ > 10 (rank : 159)	NC score	0.051681 (rank : 101)
Query Neighborhood Hits	158	Target Neighborhood Hits	87	Shared Neighborhood Hits	5
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

CENA2_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.054121 (rank : 88)
Query Neighborhood Hits	158	Target Neighborhood Hits	83	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

CENB1_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.070705 (rank : 72)
Query Neighborhood Hits	158	Target Neighborhood Hits	383	Shared Neighborhood Hits	12
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

CENB2_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.077067 (rank : 68)
Query Neighborhood Hits	158	Target Neighborhood Hits	425	Shared Neighborhood Hits	23
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

CENB5_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.071710 (rank : 71)
Query Neighborhood Hits	158	Target Neighborhood Hits	395	Shared Neighborhood Hits	10
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

CIP4_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.059677 (rank : 77)
Query Neighborhood Hits	158	Target Neighborhood Hits	374	Shared Neighborhood Hits	34
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

DDEF1_MOUSE
θ value	θ > 10 (rank : 165)	NC score	0.050964 (rank : 107)
Query Neighborhood Hits	158	Target Neighborhood Hits	592	Shared Neighborhood Hits	15
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

DDEF2_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.055825 (rank : 81)
Query Neighborhood Hits	158	Target Neighborhood Hits	599	Shared Neighborhood Hits	19
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
θ value	θ > 10 (rank : 167)	NC score	0.054236 (rank : 86)
Query Neighborhood Hits	158	Target Neighborhood Hits	625	Shared Neighborhood Hits	17
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDFL1_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.053642 (rank : 89)
Query Neighborhood Hits	158	Target Neighborhood Hits	353	Shared Neighborhood Hits	17
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

FA13A_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.069170 (rank : 74)
Query Neighborhood Hits	158	Target Neighborhood Hits	102	Shared Neighborhood Hits	7
SwissProt Accessions	O94988, Q8NBA3	Gene names	FAM13A1, KIAA0914
Domain Architecture	No domain graphic available
Description	Protein FAM13A1.

FA13A_MOUSE
θ value	θ > 10 (rank : 170)	NC score	0.069834 (rank : 73)
Query Neighborhood Hits	158	Target Neighborhood Hits	83	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BGI4, Q8BZ91	Gene names	Fam13a1, Precm1
Domain Architecture	No domain graphic available
Description	Protein FAM13A1 (Precm1 protein).

FA13C_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.053137 (rank : 92)
Query Neighborhood Hits	158	Target Neighborhood Hits	94	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NE31, Q99787	Gene names	FAM13C1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

FA13C_MOUSE
θ value	θ > 10 (rank : 172)	NC score	0.051751 (rank : 100)
Query Neighborhood Hits	158	Target Neighborhood Hits	79	Shared Neighborhood Hits	2
SwissProt Accessions	Q9DBR2	Gene names	Fam13c1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

GRAP_HUMAN
θ value	θ > 10 (rank : 173)	NC score	0.053062 (rank : 94)
Query Neighborhood Hits	158	Target Neighborhood Hits	307	Shared Neighborhood Hits	17
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

GRAP_MOUSE
θ value	θ > 10 (rank : 174)	NC score	0.050526 (rank : 109)
Query Neighborhood Hits	158	Target Neighborhood Hits	309	Shared Neighborhood Hits	17
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

GRB2_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.051370 (rank : 103)
Query Neighborhood Hits	158	Target Neighborhood Hits	310	Shared Neighborhood Hits	17
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
θ value	θ > 10 (rank : 176)	NC score	0.051362 (rank : 104)
Query Neighborhood Hits	158	Target Neighborhood Hits	312	Shared Neighborhood Hits	17
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

GRP3_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.075566 (rank : 70)
Query Neighborhood Hits	158	Target Neighborhood Hits	131	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IV61, O94931	Gene names	RASGRP3, GRP3, KIAA0846
Domain Architecture
Description	RAS guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1).

ITSN1_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.052573 (rank : 97)
Query Neighborhood Hits	158	Target Neighborhood Hits	1757	Shared Neighborhood Hits	70
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

MYH3_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.051318 (rank : 105)
Query Neighborhood Hits	158	Target Neighborhood Hits	1660	Shared Neighborhood Hits	67
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

MYO10_HUMAN
θ value	θ > 10 (rank : 180)	NC score	0.057826 (rank : 80)
Query Neighborhood Hits	158	Target Neighborhood Hits	920	Shared Neighborhood Hits	54
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

NCK2_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.058578 (rank : 79)
Query Neighborhood Hits	158	Target Neighborhood Hits	310	Shared Neighborhood Hits	19
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

P55G_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.060954 (rank : 76)
Query Neighborhood Hits	158	Target Neighborhood Hits	451	Shared Neighborhood Hits	26
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

P55G_MOUSE
θ value	θ > 10 (rank : 183)	NC score	0.061375 (rank : 75)
Query Neighborhood Hits	158	Target Neighborhood Hits	401	Shared Neighborhood Hits	30
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

P85B_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.102497 (rank : 67)
Query Neighborhood Hits	158	Target Neighborhood Hits	543	Shared Neighborhood Hits	42
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

P85B_MOUSE
θ value	θ > 10 (rank : 185)	NC score	0.075566 (rank : 69)
Query Neighborhood Hits	158	Target Neighborhood Hits	519	Shared Neighborhood Hits	39
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

PDZD8_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.054480 (rank : 84)
Query Neighborhood Hits	158	Target Neighborhood Hits	185	Shared Neighborhood Hits	12
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

SMAP1_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.052661 (rank : 95)
Query Neighborhood Hits	158	Target Neighborhood Hits	98	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SMAP1_MOUSE
θ value	θ > 10 (rank : 188)	NC score	0.052550 (rank : 98)
Query Neighborhood Hits	158	Target Neighborhood Hits	120	Shared Neighborhood Hits	5
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SMP1L_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.054253 (rank : 85)
Query Neighborhood Hits	158	Target Neighborhood Hits	74	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

SMP1L_MOUSE
θ value	θ > 10 (rank : 190)	NC score	0.054235 (rank : 87)
Query Neighborhood Hits	158	Target Neighborhood Hits	70	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

VAV3_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.053087 (rank : 93)
Query Neighborhood Hits	158	Target Neighborhood Hits	398	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

VAV3_MOUSE
θ value	θ > 10 (rank : 192)	NC score	0.052620 (rank : 96)
Query Neighborhood Hits	158	Target Neighborhood Hits	404	Shared Neighborhood Hits	21
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

Hits sorted by NC score

RHG05_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	158	Target Neighborhood Hits	158	Shared Neighborhood Hits	158
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

RHG05_MOUSE
NC score	0.995040 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	158	Target Neighborhood Hits	165	Shared Neighborhood Hits	139
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

GRLF1_HUMAN
NC score	0.964174 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	158	Target Neighborhood Hits	167	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

RHG09_HUMAN
NC score	0.774564 (rank : 4)	θ value	1.058e-16 (rank : 19)
Query Neighborhood Hits	158	Target Neighborhood Hits	186	Shared Neighborhood Hits	64
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

RHG12_MOUSE
NC score	0.757905 (rank : 5)	θ value	2.97466e-19 (rank : 12)
Query Neighborhood Hits	158	Target Neighborhood Hits	204	Shared Neighborhood Hits	69
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RHG12_HUMAN
NC score	0.756801 (rank : 6)	θ value	2.97466e-19 (rank : 11)
Query Neighborhood Hits	158	Target Neighborhood Hits	190	Shared Neighborhood Hits	67
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

CHIO_MOUSE
NC score	0.742127 (rank : 7)	θ value	3.28125e-26 (rank : 6)
Query Neighborhood Hits	158	Target Neighborhood Hits	130	Shared Neighborhood Hits	61
SwissProt Accessions	Q80XD1, Q9D9W2, Q9ER57	Gene names	Chn2, Arhgap3, Bch
Domain Architecture	No domain graphic available
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

RGAP1_HUMAN
NC score	0.741197 (rank : 8)	θ value	5.25075e-16 (rank : 24)
Query Neighborhood Hits	158	Target Neighborhood Hits	189	Shared Neighborhood Hits	73
SwissProt Accessions	Q9H0H5, Q6PJ26, Q9NWN2, Q9P250, Q9P2W2	Gene names	RACGAP1, KIAA1478, MGCRACGAP
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RGAP1_MOUSE
NC score	0.736999 (rank : 9)	θ value	1.68911e-14 (rank : 28)
Query Neighborhood Hits	158	Target Neighborhood Hits	185	Shared Neighborhood Hits	66
SwissProt Accessions	Q9WVM1, Q3THR5, Q3TI41, Q3TM81	Gene names	Racgap1, Mgcracgap
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

GMIP_MOUSE
NC score	0.731869 (rank : 10)	θ value	2.43908e-13 (rank : 38)
Query Neighborhood Hits	158	Target Neighborhood Hits	202	Shared Neighborhood Hits	65
SwissProt Accessions	Q6PGG2, Q6P9S3	Gene names	Gmip
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

3BP1_MOUSE
NC score	0.727976 (rank : 11)	θ value	2.43908e-13 (rank : 37)
Query Neighborhood Hits	158	Target Neighborhood Hits	238	Shared Neighborhood Hits	65
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

OPHN1_HUMAN
NC score	0.727278 (rank : 12)	θ value	3.88503e-19 (rank : 13)
Query Neighborhood Hits	158	Target Neighborhood Hits	161	Shared Neighborhood Hits	70
SwissProt Accessions	O60890, Q5JQ81, Q8WX47	Gene names	OPHN1
Domain Architecture
Description	Oligophrenin 1.

OPHN1_MOUSE
NC score	0.725524 (rank : 13)	θ value	1.74391e-19 (rank : 10)
Query Neighborhood Hits	158	Target Neighborhood Hits	174	Shared Neighborhood Hits	69
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

GMIP_HUMAN
NC score	0.725443 (rank : 14)	θ value	1.86753e-13 (rank : 36)
Query Neighborhood Hits	158	Target Neighborhood Hits	225	Shared Neighborhood Hits	66
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

3BP1_HUMAN
NC score	0.719086 (rank : 15)	θ value	6.20254e-17 (rank : 17)
Query Neighborhood Hits	158	Target Neighborhood Hits	376	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

CHIN_MOUSE
NC score	0.714138 (rank : 16)	θ value	3.50572e-28 (rank : 5)
Query Neighborhood Hits	158	Target Neighborhood Hits	229	Shared Neighborhood Hits	62
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIN_HUMAN
NC score	0.712541 (rank : 17)	θ value	2.05525e-28 (rank : 4)
Query Neighborhood Hits	158	Target Neighborhood Hits	227	Shared Neighborhood Hits	61
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIO_HUMAN
NC score	0.710795 (rank : 18)	θ value	2.12685e-25 (rank : 7)
Query Neighborhood Hits	158	Target Neighborhood Hits	220	Shared Neighborhood Hits	61
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

RHG01_HUMAN
NC score	0.703387 (rank : 19)	θ value	7.09661e-13 (rank : 39)
Query Neighborhood Hits	158	Target Neighborhood Hits	75	Shared Neighborhood Hits	62
SwissProt Accessions	Q07960	Gene names	ARHGAP1, CDC42GAP, RHOGAP1
Domain Architecture
Description	Rho-GTPase-activating protein 1 (GTPase-activating protein rhoOGAP) (Rho-related small GTPase protein activator) (CDC42 GTPase-activating protein) (p50-RhoGAP).

RHG06_HUMAN
NC score	0.697146 (rank : 20)	θ value	2.13673e-09 (rank : 50)
Query Neighborhood Hits	158	Target Neighborhood Hits	114	Shared Neighborhood Hits	62
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RHG06_MOUSE
NC score	0.692908 (rank : 21)	θ value	8.11959e-09 (rank : 52)
Query Neighborhood Hits	158	Target Neighborhood Hits	105	Shared Neighborhood Hits	62
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

TCGAP_MOUSE
NC score	0.689424 (rank : 22)	θ value	4.91457e-14 (rank : 32)
Query Neighborhood Hits	158	Target Neighborhood Hits	409	Shared Neighborhood Hits	66
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

ABR_HUMAN
NC score	0.684868 (rank : 23)	θ value	2.06002e-20 (rank : 8)
Query Neighborhood Hits	158	Target Neighborhood Hits	166	Shared Neighborhood Hits	62
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

RHG08_MOUSE
NC score	0.680950 (rank : 24)	θ value	1.47974e-10 (rank : 44)
Query Neighborhood Hits	158	Target Neighborhood Hits	73	Shared Neighborhood Hits	62
SwissProt Accessions	Q9CXP4, Q99JY7	Gene names	Arhgap8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RHG08_HUMAN
NC score	0.680465 (rank : 25)	θ value	1.33837e-11 (rank : 43)
Query Neighborhood Hits	158	Target Neighborhood Hits	88	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NSG0, O75983, O95695, Q96RW1, Q96RW2, Q9HA49, Q9HC46, Q9NVX8, Q9NXL1, Q9UH20	Gene names	ARHGAP8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RHG26_HUMAN
NC score	0.676217 (rank : 26)	θ value	4.02038e-16 (rank : 23)
Query Neighborhood Hits	158	Target Neighborhood Hits	281	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

RHG18_HUMAN
NC score	0.674161 (rank : 27)	θ value	4.0297e-08 (rank : 55)
Query Neighborhood Hits	158	Target Neighborhood Hits	90	Shared Neighborhood Hits	63
SwissProt Accessions	Q8N392, Q58EZ3, Q6P679, Q6PJD7, Q96S64	Gene names	ARHGAP18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18 (MacGAP).

RHG18_MOUSE
NC score	0.673764 (rank : 28)	θ value	6.21693e-09 (rank : 51)
Query Neighborhood Hits	158	Target Neighborhood Hits	110	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K0Q5, Q8BP03, Q8R196	Gene names	Arhgap18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18.

RHG04_HUMAN
NC score	0.673044 (rank : 29)	θ value	9.56915e-18 (rank : 15)
Query Neighborhood Hits	158	Target Neighborhood Hits	307	Shared Neighborhood Hits	69
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

BCR_HUMAN
NC score	0.672102 (rank : 30)	θ value	2.06002e-20 (rank : 9)
Query Neighborhood Hits	158	Target Neighborhood Hits	204	Shared Neighborhood Hits	62
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

RBP1_MOUSE
NC score	0.665459 (rank : 31)	θ value	3.52202e-12 (rank : 42)
Query Neighborhood Hits	158	Target Neighborhood Hits	493	Shared Neighborhood Hits	88
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

SRGP2_HUMAN
NC score	0.664917 (rank : 32)	θ value	2.5182e-18 (rank : 14)
Query Neighborhood Hits	158	Target Neighborhood Hits	331	Shared Neighborhood Hits	74
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

RHG25_MOUSE
NC score	0.659236 (rank : 33)	θ value	1.42992e-13 (rank : 34)
Query Neighborhood Hits	158	Target Neighborhood Hits	492	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

SRGP2_MOUSE
NC score	0.658223 (rank : 34)	θ value	9.56915e-18 (rank : 16)
Query Neighborhood Hits	158	Target Neighborhood Hits	324	Shared Neighborhood Hits	75
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

RBP1_HUMAN
NC score	0.656637 (rank : 35)	θ value	3.76295e-14 (rank : 30)
Query Neighborhood Hits	158	Target Neighborhood Hits	521	Shared Neighborhood Hits	91
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

SRGP1_HUMAN
NC score	0.653801 (rank : 36)	θ value	3.07829e-16 (rank : 22)
Query Neighborhood Hits	158	Target Neighborhood Hits	390	Shared Neighborhood Hits	82
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

TAGAP_HUMAN
NC score	0.651984 (rank : 37)	θ value	3.29651e-10 (rank : 45)
Query Neighborhood Hits	158	Target Neighborhood Hits	82	Shared Neighborhood Hits	62
SwissProt Accessions	Q8N103, Q2NKM8, Q8NI40, Q96KZ2, Q96QA2	Gene names	TAGAP, TAGAP1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

FNBP2_HUMAN
NC score	0.648444 (rank : 38)	θ value	4.44505e-15 (rank : 27)
Query Neighborhood Hits	158	Target Neighborhood Hits	432	Shared Neighborhood Hits	78
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

TAGAP_MOUSE
NC score	0.639735 (rank : 39)	θ value	5.26297e-08 (rank : 56)
Query Neighborhood Hits	158	Target Neighborhood Hits	83	Shared Neighborhood Hits	60
SwissProt Accessions	Q8K2L9, Q920D6	Gene names	Tagap, Tagap1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

RHG25_HUMAN
NC score	0.637753 (rank : 40)	θ value	2.0648e-12 (rank : 41)
Query Neighborhood Hits	158	Target Neighborhood Hits	550	Shared Neighborhood Hits	83
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

TCGAP_HUMAN
NC score	0.612141 (rank : 41)	θ value	4.91457e-14 (rank : 31)
Query Neighborhood Hits	158	Target Neighborhood Hits	872	Shared Neighborhood Hits	69
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

CEND2_HUMAN
NC score	0.611763 (rank : 42)	θ value	1.058e-16 (rank : 18)
Query Neighborhood Hits	158	Target Neighborhood Hits	166	Shared Neighborhood Hits	60
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

RHG07_MOUSE
NC score	0.605662 (rank : 43)	θ value	9.59137e-10 (rank : 49)
Query Neighborhood Hits	158	Target Neighborhood Hits	103	Shared Neighborhood Hits	66
SwissProt Accessions	Q9R0Z9, Q8R541	Gene names	Dlc1, Arhgap7, Stard12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein homolog) (Dlc-1) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

CE005_HUMAN
NC score	0.604787 (rank : 44)	θ value	8.38298e-14 (rank : 33)
Query Neighborhood Hits	158	Target Neighborhood Hits	213	Shared Neighborhood Hits	76
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

CE005_MOUSE
NC score	0.603382 (rank : 45)	θ value	2.20605e-14 (rank : 29)
Query Neighborhood Hits	158	Target Neighborhood Hits	238	Shared Neighborhood Hits	76
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

RHG07_HUMAN
NC score	0.598652 (rank : 46)	θ value	9.59137e-10 (rank : 48)
Query Neighborhood Hits	158	Target Neighborhood Hits	108	Shared Neighborhood Hits	64
SwissProt Accessions	Q96QB1, O14868, O43199, Q9C0E0	Gene names	DLC1, ARHGAP7, KIAA1723, STARD12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein) (Dlc-1) (HP protein) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

CEND3_MOUSE
NC score	0.576708 (rank : 47)	θ value	3.40345e-15 (rank : 26)
Query Neighborhood Hits	158	Target Neighborhood Hits	228	Shared Neighborhood Hits	61
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

CEND3_HUMAN
NC score	0.565391 (rank : 48)	θ value	3.40345e-15 (rank : 25)
Query Neighborhood Hits	158	Target Neighborhood Hits	275	Shared Neighborhood Hits	60
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

STA13_HUMAN
NC score	0.563566 (rank : 49)	θ value	1.06045e-08 (rank : 53)
Query Neighborhood Hits	158	Target Neighborhood Hits	89	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y3M8, Q5HYH1, Q5TAE3, Q6UN61, Q86TP6, Q86WQ3, Q86XT1	Gene names	STARD13, DLC2, GT650
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13) (46H23.2) (Deleted in liver cancer protein 2) (Rho GTPase-activating protein).

STAR8_MOUSE
NC score	0.556635 (rank : 50)	θ value	8.40245e-06 (rank : 60)
Query Neighborhood Hits	158	Target Neighborhood Hits	101	Shared Neighborhood Hits	59
SwissProt Accessions	Q8K031, Q3UZC7, Q6A0A8, Q6P5E0, Q8R3X8	Gene names	Stard8, Kiaa0189
Domain Architecture	No domain graphic available
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

STAR8_HUMAN
NC score	0.552230 (rank : 51)	θ value	1.29631e-06 (rank : 59)
Query Neighborhood Hits	158	Target Neighborhood Hits	216	Shared Neighborhood Hits	59
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

STA13_MOUSE
NC score	0.552038 (rank : 52)	θ value	1.17247e-07 (rank : 58)
Query Neighborhood Hits	158	Target Neighborhood Hits	89	Shared Neighborhood Hits	58
SwissProt Accessions	Q923Q2, Q8K369	Gene names	Stard13
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13).

CEND1_MOUSE
NC score	0.527823 (rank : 53)	θ value	1.86753e-13 (rank : 35)
Query Neighborhood Hits	158	Target Neighborhood Hits	260	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

CEND1_HUMAN
NC score	0.506706 (rank : 54)	θ value	9.26847e-13 (rank : 40)
Query Neighborhood Hits	158	Target Neighborhood Hits	284	Shared Neighborhood Hits	56
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

K1688_MOUSE
NC score	0.431187 (rank : 55)	θ value	0.813845 (rank : 89)
Query Neighborhood Hits	158	Target Neighborhood Hits	188	Shared Neighborhood Hits	63
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

K1688_HUMAN
NC score	0.419454 (rank : 56)	θ value	4.03905 (rank : 120)
Query Neighborhood Hits	158	Target Neighborhood Hits	217	Shared Neighborhood Hits	63
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

MYO9B_MOUSE
NC score	0.396938 (rank : 57)	θ value	1.80466e-16 (rank : 21)
Query Neighborhood Hits	158	Target Neighborhood Hits	311	Shared Neighborhood Hits	74
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

MYO9B_HUMAN
NC score	0.391274 (rank : 58)	θ value	1.38178e-16 (rank : 20)
Query Neighborhood Hits	158	Target Neighborhood Hits	641	Shared Neighborhood Hits	74
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

P85A_HUMAN
NC score	0.379721 (rank : 59)	θ value	8.97725e-08 (rank : 57)
Query Neighborhood Hits	158	Target Neighborhood Hits	479	Shared Neighborhood Hits	77
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

P85A_MOUSE
NC score	0.376212 (rank : 60)	θ value	4.0297e-08 (rank : 54)
Query Neighborhood Hits	158	Target Neighborhood Hits	435	Shared Neighborhood Hits	72
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

I5P2_HUMAN
NC score	0.312426 (rank : 61)	θ value	0.00665767 (rank : 63)
Query Neighborhood Hits	158	Target Neighborhood Hits	86	Shared Neighborhood Hits	52
SwissProt Accessions	P32019, Q5VSG9, Q5VSH0, Q5VSH1, Q658Q5, Q6P6D4, Q6PD53, Q86YE1	Gene names	INPP5B
Domain Architecture	No domain graphic available
Description	Type II inositol-1,4,5-trisphosphate 5-phosphatase precursor (EC 3.1.3.36) (Phosphoinositide 5-phosphatase) (5PTase) (75 kDa inositol polyphosphate-5-phosphatase).

OCRL_HUMAN
NC score	0.304501 (rank : 62)	θ value	0.000786445 (rank : 62)
Query Neighborhood Hits	158	Target Neighborhood Hits	77	Shared Neighborhood Hits	51
SwissProt Accessions	Q01968, O60800, Q15684, Q15774, Q5JQF1, Q5JQF2, Q9UJG5, Q9UMA5	Gene names	OCRL, INPP5F, OCRL1
Domain Architecture
Description	Inositol polyphosphate 5-phosphatase OCRL-1 (EC 3.1.3.36) (Lowe oculocerebrorenal syndrome protein).

TCRG1_HUMAN
NC score	0.164713 (rank : 63)	θ value	5.62301e-10 (rank : 46)
Query Neighborhood Hits	158	Target Neighborhood Hits	929	Shared Neighborhood Hits	49
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TCRG1_MOUSE
NC score	0.164106 (rank : 64)	θ value	5.62301e-10 (rank : 47)
Query Neighborhood Hits	158	Target Neighborhood Hits	947	Shared Neighborhood Hits	51
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

PRP40_MOUSE
NC score	0.115148 (rank : 65)	θ value	0.0148317 (rank : 66)
Query Neighborhood Hits	158	Target Neighborhood Hits	447	Shared Neighborhood Hits	29
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

PRP40_HUMAN
NC score	0.109320 (rank : 66)	θ value	0.0148317 (rank : 65)
Query Neighborhood Hits	158	Target Neighborhood Hits	442	Shared Neighborhood Hits	25
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

P85B_HUMAN
NC score	0.102497 (rank : 67)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	158	Target Neighborhood Hits	543	Shared Neighborhood Hits	42
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

CENB2_HUMAN
NC score	0.077067 (rank : 68)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	158	Target Neighborhood Hits	425	Shared Neighborhood Hits	23
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

P85B_MOUSE
NC score	0.075566 (rank : 69)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	158	Target Neighborhood Hits	519	Shared Neighborhood Hits	39
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

GRP3_HUMAN
NC score	0.075566 (rank : 70)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	158	Target Neighborhood Hits	131	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IV61, O94931	Gene names	RASGRP3, GRP3, KIAA0846
Domain Architecture
Description	RAS guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1).

CENB5_HUMAN
NC score	0.071710 (rank : 71)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	158	Target Neighborhood Hits	395	Shared Neighborhood Hits	10
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

CENB1_HUMAN
NC score	0.070705 (rank : 72)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	158	Target Neighborhood Hits	383	Shared Neighborhood Hits	12
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

FA13A_MOUSE
NC score	0.069834 (rank : 73)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	158	Target Neighborhood Hits	83	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BGI4, Q8BZ91	Gene names	Fam13a1, Precm1
Domain Architecture	No domain graphic available
Description	Protein FAM13A1 (Precm1 protein).

FA13A_HUMAN
NC score	0.069170 (rank : 74)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	158	Target Neighborhood Hits	102	Shared Neighborhood Hits	7
SwissProt Accessions	O94988, Q8NBA3	Gene names	FAM13A1, KIAA0914
Domain Architecture	No domain graphic available
Description	Protein FAM13A1.

P55G_MOUSE
NC score	0.061375 (rank : 75)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	158	Target Neighborhood Hits	401	Shared Neighborhood Hits	30
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

P55G_HUMAN
NC score	0.060954 (rank : 76)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	158	Target Neighborhood Hits	451	Shared Neighborhood Hits	26
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

CIP4_HUMAN
NC score	0.059677 (rank : 77)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	158	Target Neighborhood Hits	374	Shared Neighborhood Hits	34
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

PAWR_HUMAN
NC score	0.059676 (rank : 78)	θ value	0.47712 (rank : 77)
Query Neighborhood Hits	158	Target Neighborhood Hits	252	Shared Neighborhood Hits	17
SwissProt Accessions	Q96IZ0, O75796, Q6FHY9, Q8N700	Gene names	PAWR, PAR4
Domain Architecture	No domain graphic available
Description	PRKC apoptosis WT1 regulator protein (Prostate apoptosis response 4 protein) (Par-4).

NCK2_HUMAN
NC score	0.058578 (rank : 79)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	158	Target Neighborhood Hits	310	Shared Neighborhood Hits	19
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

MYO10_HUMAN
NC score	0.057826 (rank : 80)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	158	Target Neighborhood Hits	920	Shared Neighborhood Hits	54
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

DDEF2_HUMAN
NC score	0.055825 (rank : 81)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	158	Target Neighborhood Hits	599	Shared Neighborhood Hits	19
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

IF3A_HUMAN
NC score	0.055275 (rank : 82)	θ value	0.62314 (rank : 82)
Query Neighborhood Hits	158	Target Neighborhood Hits	875	Shared Neighborhood Hits	46
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

COG8_HUMAN
NC score	0.055133 (rank : 83)	θ value	0.21417 (rank : 72)
Query Neighborhood Hits	158	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q96MW5, Q8WVV6, Q9H6F8	Gene names	COG8
Domain Architecture
Description	Conserved oligomeric Golgi complex component 8.

PDZD8_HUMAN
NC score	0.054480 (rank : 84)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	158	Target Neighborhood Hits	185	Shared Neighborhood Hits	12
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

SMP1L_HUMAN
NC score	0.054253 (rank : 85)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	158	Target Neighborhood Hits	74	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

DDEF2_MOUSE
NC score	0.054236 (rank : 86)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	158	Target Neighborhood Hits	625	Shared Neighborhood Hits	17
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

SMP1L_MOUSE
NC score	0.054235 (rank : 87)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	158	Target Neighborhood Hits	70	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

CENA2_HUMAN
NC score	0.054121 (rank : 88)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	158	Target Neighborhood Hits	83	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

DDFL1_HUMAN
NC score	0.053642 (rank : 89)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	158	Target Neighborhood Hits	353	Shared Neighborhood Hits	17
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

MYH8_HUMAN
NC score	0.053344 (rank : 90)	θ value	1.06291 (rank : 94)
Query Neighborhood Hits	158	Target Neighborhood Hits	1610	Shared Neighborhood Hits	65
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

IF3A_MOUSE
NC score	0.053257 (rank : 91)	θ value	1.38821 (rank : 97)
Query Neighborhood Hits	158	Target Neighborhood Hits	871	Shared Neighborhood Hits	48
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

FA13C_HUMAN
NC score	0.053137 (rank : 92)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	158	Target Neighborhood Hits	94	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NE31, Q99787	Gene names	FAM13C1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

VAV3_HUMAN
NC score	0.053087 (rank : 93)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	158	Target Neighborhood Hits	398	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

GRAP_HUMAN
NC score	0.053062 (rank : 94)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	158	Target Neighborhood Hits	307	Shared Neighborhood Hits	17
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

SMAP1_HUMAN
NC score	0.052661 (rank : 95)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	158	Target Neighborhood Hits	98	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

VAV3_MOUSE
NC score	0.052620 (rank : 96)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	158	Target Neighborhood Hits	404	Shared Neighborhood Hits	21
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

ITSN1_HUMAN
NC score	0.052573 (rank : 97)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	158	Target Neighborhood Hits	1757	Shared Neighborhood Hits	70
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

SMAP1_MOUSE
NC score	0.052550 (rank : 98)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	158	Target Neighborhood Hits	120	Shared Neighborhood Hits	5
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

MYH1_MOUSE
NC score	0.051953 (rank : 99)	θ value	0.47712 (rank : 76)
Query Neighborhood Hits	158	Target Neighborhood Hits	1461	Shared Neighborhood Hits	68
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

FA13C_MOUSE
NC score	0.051751 (rank : 100)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	158	Target Neighborhood Hits	79	Shared Neighborhood Hits	2
SwissProt Accessions	Q9DBR2	Gene names	Fam13c1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

CENA1_HUMAN
NC score	0.051681 (rank : 101)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	158	Target Neighborhood Hits	87	Shared Neighborhood Hits	5
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

MYH4_HUMAN
NC score	0.051527 (rank : 102)	θ value	1.81305 (rank : 103)
Query Neighborhood Hits	158	Target Neighborhood Hits	1377	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

GRB2_HUMAN
NC score	0.051370 (rank : 103)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	158	Target Neighborhood Hits	310	Shared Neighborhood Hits	17
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
NC score	0.051362 (rank : 104)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	158	Target Neighborhood Hits	312	Shared Neighborhood Hits	17
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

MYH3_HUMAN
NC score	0.051318 (rank : 105)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	158	Target Neighborhood Hits	1660	Shared Neighborhood Hits	67
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

NIN_HUMAN
NC score	0.051253 (rank : 106)	θ value	0.125558 (rank : 70)
Query Neighborhood Hits	158	Target Neighborhood Hits	1416	Shared Neighborhood Hits	64
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

DDEF1_MOUSE
NC score	0.050964 (rank : 107)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	158	Target Neighborhood Hits	592	Shared Neighborhood Hits	15
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

MYH8_MOUSE
NC score	0.050930 (rank : 108)	θ value	2.36792 (rank : 109)
Query Neighborhood Hits	158	Target Neighborhood Hits	1600	Shared Neighborhood Hits	63
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

GRAP_MOUSE
NC score	0.050526 (rank : 109)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	158	Target Neighborhood Hits	309	Shared Neighborhood Hits	17
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

SPTA1_HUMAN
NC score	0.050326 (rank : 110)	θ value	1.06291 (rank : 96)
Query Neighborhood Hits	158	Target Neighborhood Hits	748	Shared Neighborhood Hits	49
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

MYH1_HUMAN
NC score	0.049937 (rank : 111)	θ value	3.0926 (rank : 116)
Query Neighborhood Hits	158	Target Neighborhood Hits	1478	Shared Neighborhood Hits	63
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

MYH2_HUMAN
NC score	0.049614 (rank : 112)	θ value	0.62314 (rank : 83)
Query Neighborhood Hits	158	Target Neighborhood Hits	1491	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

SPTA1_MOUSE
NC score	0.048221 (rank : 113)	θ value	1.81305 (rank : 106)
Query Neighborhood Hits	158	Target Neighborhood Hits	675	Shared Neighborhood Hits	46
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

MORC4_HUMAN
NC score	0.048074 (rank : 114)	θ value	0.0736092 (rank : 69)
Query Neighborhood Hits	158	Target Neighborhood Hits	244	Shared Neighborhood Hits	23
SwissProt Accessions	Q8TE76, Q5JUK7, Q96MZ2, Q9HAI7	Gene names	MORC4, ZCWCC2
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 4 (Zinc finger CW-type coiled- coil domain protein 2).

MYH4_MOUSE
NC score	0.047839 (rank : 115)	θ value	8.99809 (rank : 154)
Query Neighborhood Hits	158	Target Neighborhood Hits	1476	Shared Neighborhood Hits	65
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

CENPF_HUMAN
NC score	0.047260 (rank : 116)	θ value	0.0736092 (rank : 68)
Query Neighborhood Hits	158	Target Neighborhood Hits	1932	Shared Neighborhood Hits	70
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

RAD50_MOUSE
NC score	0.045534 (rank : 117)	θ value	0.125558 (rank : 71)
Query Neighborhood Hits	158	Target Neighborhood Hits	1366	Shared Neighborhood Hits	54
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

CI093_HUMAN
NC score	0.045310 (rank : 118)	θ value	4.03905 (rank : 119)
Query Neighborhood Hits	158	Target Neighborhood Hits	1088	Shared Neighborhood Hits	57
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

RAD50_HUMAN
NC score	0.044080 (rank : 119)	θ value	0.365318 (rank : 75)
Query Neighborhood Hits	158	Target Neighborhood Hits	1317	Shared Neighborhood Hits	52
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

GOGB1_HUMAN
NC score	0.043642 (rank : 120)	θ value	0.813845 (rank : 88)
Query Neighborhood Hits	158	Target Neighborhood Hits	2297	Shared Neighborhood Hits	73
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

SYNE1_HUMAN
NC score	0.043185 (rank : 121)	θ value	0.0193708 (rank : 67)
Query Neighborhood Hits	158	Target Neighborhood Hits	1484	Shared Neighborhood Hits	60
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

CCD11_HUMAN
NC score	0.042978 (rank : 122)	θ value	1.81305 (rank : 100)
Query Neighborhood Hits	158	Target Neighborhood Hits	822	Shared Neighborhood Hits	43
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

KTN1_HUMAN
NC score	0.042066 (rank : 123)	θ value	0.365318 (rank : 74)
Query Neighborhood Hits	158	Target Neighborhood Hits	1197	Shared Neighborhood Hits	51
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

TRIPB_HUMAN
NC score	0.042010 (rank : 124)	θ value	0.21417 (rank : 73)
Query Neighborhood Hits	158	Target Neighborhood Hits	1587	Shared Neighborhood Hits	61
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

CA065_HUMAN
NC score	0.041868 (rank : 125)	θ value	2.36792 (rank : 107)
Query Neighborhood Hits	158	Target Neighborhood Hits	469	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N715, Q8N746, Q8NA93	Gene names	C1orf65
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf65.

CCD46_HUMAN
NC score	0.041866 (rank : 126)	θ value	8.99809 (rank : 150)
Query Neighborhood Hits	158	Target Neighborhood Hits	1430	Shared Neighborhood Hits	67
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

TACC3_MOUSE
NC score	0.038915 (rank : 127)	θ value	0.813845 (rank : 92)
Query Neighborhood Hits	158	Target Neighborhood Hits	607	Shared Neighborhood Hits	39
SwissProt Accessions	Q9JJ11, Q9WVK9	Gene names	Tacc3, Aint
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ARNT-interacting protein).

G45IP_HUMAN
NC score	0.035465 (rank : 128)	θ value	1.81305 (rank : 102)
Query Neighborhood Hits	158	Target Neighborhood Hits	118	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TAE8, Q8IVM3, Q8TE51, Q969P9, Q9BSM6	Gene names	GADD45GIP1, PLINP1
Domain Architecture	No domain graphic available
Description	Growth arrest and DNA-damage-inducible proteins-interacting protein 1 (CR6-interacting factor 1) (CRIF1) (CKII beta-associating protein) (Papillomavirus L2-interacting nuclear protein 1) (PLINP-1).

TXLNA_MOUSE
NC score	0.033999 (rank : 129)	θ value	2.36792 (rank : 110)
Query Neighborhood Hits	158	Target Neighborhood Hits	846	Shared Neighborhood Hits	40
SwissProt Accessions	Q6PAM1, Q6P1E5	Gene names	Txlna, Txln
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

COG8_MOUSE
NC score	0.033660 (rank : 130)	θ value	8.99809 (rank : 151)
Query Neighborhood Hits	158	Target Neighborhood Hits	147	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JJA2	Gene names	Cog8
Domain Architecture
Description	Conserved oligomeric Golgi complex component 8.

TXLNA_HUMAN
NC score	0.032989 (rank : 131)	θ value	3.0926 (rank : 118)
Query Neighborhood Hits	158	Target Neighborhood Hits	982	Shared Neighborhood Hits	43
SwissProt Accessions	P40222, Q66K62, Q86T54, Q86T85, Q86T86, Q86Y86, Q86YW3, Q8N2Y3	Gene names	TXLNA, TXLN
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

FAF1_MOUSE
NC score	0.032822 (rank : 132)	θ value	3.0926 (rank : 112)
Query Neighborhood Hits	158	Target Neighborhood Hits	107	Shared Neighborhood Hits	17
SwissProt Accessions	P54731	Gene names	Faf1
Domain Architecture
Description	FAS-associated factor 1 (Protein FAF1).

CTRO_MOUSE
NC score	0.032024 (rank : 133)	θ value	4.1701e-05 (rank : 61)
Query Neighborhood Hits	158	Target Neighborhood Hits	2344	Shared Neighborhood Hits	63
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

BCAR1_MOUSE
NC score	0.030761 (rank : 134)	θ value	8.99809 (rank : 148)
Query Neighborhood Hits	158	Target Neighborhood Hits	438	Shared Neighborhood Hits	18
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

FAF1_HUMAN
NC score	0.029416 (rank : 135)	θ value	5.27518 (rank : 127)
Query Neighborhood Hits	158	Target Neighborhood Hits	105	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UNN5, Q9UF34, Q9UNT3, Q9Y2Z3	Gene names	FAF1
Domain Architecture
Description	FAS-associated factor 1 (Protein FAF1) (hFAF1).

MORC4_MOUSE
NC score	0.028820 (rank : 136)	θ value	3.0926 (rank : 115)
Query Neighborhood Hits	158	Target Neighborhood Hits	235	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BMD7, Q4KMM6, Q8BX95, Q9CS96	Gene names	Morc4, Zcwcc2
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 4 (Zinc finger CW-type coiled- coil domain protein 2).

CYLN2_HUMAN
NC score	0.028697 (rank : 137)	θ value	8.99809 (rank : 152)
Query Neighborhood Hits	158	Target Neighborhood Hits	1004	Shared Neighborhood Hits	48
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

K0423_HUMAN
NC score	0.027845 (rank : 138)	θ value	3.0926 (rank : 113)
Query Neighborhood Hits	158	Target Neighborhood Hits	171	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y4F4, Q68D66, Q6PG27	Gene names	KIAA0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

AASS_HUMAN
NC score	0.026186 (rank : 139)	θ value	1.81305 (rank : 99)
Query Neighborhood Hits	158	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UDR5, O95462	Gene names	AASS
Domain Architecture
Description	Alpha-aminoadipic semialdehyde synthase, mitochondrial precursor (LKR/SDH) [Includes: Lysine ketoglutarate reductase (EC 1.5.1.8) (LOR) (LKR); Saccharopine dehydrogenase (EC 1.5.1.9) (SDH)].

WDR67_HUMAN
NC score	0.025209 (rank : 140)	θ value	4.03905 (rank : 124)
Query Neighborhood Hits	158	Target Neighborhood Hits	782	Shared Neighborhood Hits	39
SwissProt Accessions	Q96DN5, Q3MIR6, Q8TBP9	Gene names	WDR67
Domain Architecture	No domain graphic available
Description	WD repeat protein 67.

K0423_MOUSE
NC score	0.025085 (rank : 141)	θ value	3.0926 (rank : 114)
Query Neighborhood Hits	158	Target Neighborhood Hits	115	Shared Neighborhood Hits	6
SwissProt Accessions	Q6A070	Gene names	Kiaa0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

DTBP1_HUMAN
NC score	0.024877 (rank : 142)	θ value	2.36792 (rank : 108)
Query Neighborhood Hits	158	Target Neighborhood Hits	185	Shared Neighborhood Hits	22
SwissProt Accessions	Q96EV8, Q96NV2, Q9H0U2, Q9H3J5	Gene names	DTNBP1
Domain Architecture
Description	Dystrobrevin-binding protein 1 (Dysbindin) (Hermansky-Pudlak syndrome 7 protein).

SIN3A_MOUSE
NC score	0.024305 (rank : 143)	θ value	3.0926 (rank : 117)
Query Neighborhood Hits	158	Target Neighborhood Hits	169	Shared Neighborhood Hits	11
SwissProt Accessions	Q60520, Q60820, Q62139, Q62140, Q7TPU8, Q7TSZ2	Gene names	Sin3a
Domain Architecture
Description	Paired amphipathic helix protein Sin3a (Transcriptional corepressor Sin3a) (Histone deacetylase complex subunit Sin3a).

COVA1_HUMAN
NC score	0.023562 (rank : 144)	θ value	1.81305 (rank : 101)
Query Neighborhood Hits	158	Target Neighborhood Hits	416	Shared Neighborhood Hits	21
SwissProt Accessions	Q16206, Q5VTJ1, Q5VTJ2, Q8WUX0, Q9NTP6, Q9UH82	Gene names	COVA1
Domain Architecture
Description	Tumor-associated hydroquinone oxidase (tNOX) (Cytosolic ovarian carcinoma antigen 1) (APK1 antigen) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)].

SCYL2_MOUSE
NC score	0.023069 (rank : 145)	θ value	0.62314 (rank : 86)
Query Neighborhood Hits	158	Target Neighborhood Hits	603	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CFE4, Q3UT57, Q3UWU9, Q8K0M4	Gene names	Scyl2, Cvak104, D10Ertd802e
Domain Architecture	No domain graphic available
Description	SCY1-like protein 2 (Coated vesicle-associated kinase of 104 kDa).

LAMA3_HUMAN
NC score	0.022871 (rank : 146)	θ value	1.06291 (rank : 93)
Query Neighborhood Hits	158	Target Neighborhood Hits	760	Shared Neighborhood Hits	32
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

CTRO_HUMAN
NC score	0.022782 (rank : 147)	θ value	0.62314 (rank : 81)
Query Neighborhood Hits	158	Target Neighborhood Hits	2092	Shared Neighborhood Hits	60
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

PIGN_HUMAN
NC score	0.022524 (rank : 148)	θ value	4.03905 (rank : 121)
Query Neighborhood Hits	158	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	O95427, Q7L8F8, Q8TC01, Q9NT05	Gene names	PIGN, MCD4
Domain Architecture	No domain graphic available
Description	GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class N protein) (PIG-N) (MCD4 homolog).

SEN54_MOUSE
NC score	0.022512 (rank : 149)	θ value	4.03905 (rank : 123)
Query Neighborhood Hits	158	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C2A2, Q9DCI5	Gene names	Tsen54, Sen54
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen54 (tRNA-intron endonuclease Sen54).

SIN3A_HUMAN
NC score	0.022258 (rank : 150)	θ value	5.27518 (rank : 133)
Query Neighborhood Hits	158	Target Neighborhood Hits	180	Shared Neighborhood Hits	10
SwissProt Accessions	Q96ST3, Q8N8N4, Q8NC83, Q8WV18, Q96L98, Q9UFQ1	Gene names	SIN3A
Domain Architecture
Description	Paired amphipathic helix protein Sin3a (Transcriptional corepressor Sin3a) (Histone deacetylase complex subunit Sin3a).

SCYL2_HUMAN
NC score	0.021553 (rank : 151)	θ value	0.47712 (rank : 78)
Query Neighborhood Hits	158	Target Neighborhood Hits	632	Shared Neighborhood Hits	11
SwissProt Accessions	Q6P3W7, Q96EF4, Q96ST4, Q9H7V5, Q9NVH3, Q9P2I7	Gene names	SCYL2, CVAK104, KIAA1360
Domain Architecture	No domain graphic available
Description	SCY1-like protein 2 (Coated vesicle-associated kinase of 104 kDa).

PROX1_MOUSE
NC score	0.020418 (rank : 152)	θ value	4.03905 (rank : 122)
Query Neighborhood Hits	158	Target Neighborhood Hits	184	Shared Neighborhood Hits	11
SwissProt Accessions	P48437, O88478, Q3UPV1, Q543D8	Gene names	Prox1
Domain Architecture
Description	Homeobox prospero-like protein PROX1 (PROX 1).

PIGN_MOUSE
NC score	0.019556 (rank : 153)	θ value	6.88961 (rank : 140)
Query Neighborhood Hits	158	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q9R1S3, Q3V0S6, Q8VCC3, Q9R1S1, Q9R1S2	Gene names	Pign
Domain Architecture	No domain graphic available
Description	GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class N protein) (PIG-N).

AN30A_HUMAN
NC score	0.017745 (rank : 154)	θ value	8.99809 (rank : 147)
Query Neighborhood Hits	158	Target Neighborhood Hits	1119	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

RAB4B_MOUSE
NC score	0.017185 (rank : 155)	θ value	0.62314 (rank : 85)
Query Neighborhood Hits	158	Target Neighborhood Hits	283	Shared Neighborhood Hits	13
SwissProt Accessions	Q91ZR1	Gene names	Rab4b, Rab4
Domain Architecture
Description	Ras-related protein Rab-4B.

RAB4B_HUMAN
NC score	0.017183 (rank : 156)	θ value	0.62314 (rank : 84)
Query Neighborhood Hits	158	Target Neighborhood Hits	283	Shared Neighborhood Hits	13
SwissProt Accessions	P61018, P22750, Q7Z514, Q9HBR6	Gene names	RAB4B
Domain Architecture
Description	Ras-related protein Rab-4B.

MYCN_MOUSE
NC score	0.015825 (rank : 157)	θ value	5.27518 (rank : 130)
Query Neighborhood Hits	158	Target Neighborhood Hits	125	Shared Neighborhood Hits	5
SwissProt Accessions	P03966, Q61978	Gene names	Mycn, Nmyc, Nmyc1
Domain Architecture
Description	N-myc proto-oncogene protein.

MYCN_HUMAN
NC score	0.015626 (rank : 158)	θ value	5.27518 (rank : 129)
Query Neighborhood Hits	158	Target Neighborhood Hits	127	Shared Neighborhood Hits	5
SwissProt Accessions	P04198, Q6LDT9	Gene names	MYCN, NMYC
Domain Architecture
Description	N-myc proto-oncogene protein.

RAB4A_HUMAN
NC score	0.015418 (rank : 159)	θ value	0.813845 (rank : 91)
Query Neighborhood Hits	158	Target Neighborhood Hits	275	Shared Neighborhood Hits	12
SwissProt Accessions	P20338, Q9BQ44	Gene names	RAB4A, RAB4
Domain Architecture
Description	Ras-related protein Rab-4A.

YLPM1_HUMAN
NC score	0.015324 (rank : 160)	θ value	8.99809 (rank : 158)
Query Neighborhood Hits	158	Target Neighborhood Hits	670	Shared Neighborhood Hits	11
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

CA048_HUMAN
NC score	0.015145 (rank : 161)	θ value	8.99809 (rank : 149)
Query Neighborhood Hits	158	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q96IY1, Q5SY75, Q9H2M5, Q9NRN8, Q9Y415	Gene names	C1orf48
Domain Architecture	No domain graphic available
Description	Protein C1orf48.

NUCB1_HUMAN
NC score	0.014921 (rank : 162)	θ value	8.99809 (rank : 156)
Query Neighborhood Hits	158	Target Neighborhood Hits	359	Shared Neighborhood Hits	24
SwissProt Accessions	Q02818, Q15838, Q7Z4J7, Q9BUR1	Gene names	NUCB1, NUC
Domain Architecture	No domain graphic available
Description	Nucleobindin-1 precursor (CALNUC).

RAB4A_MOUSE
NC score	0.014455 (rank : 163)	θ value	1.38821 (rank : 98)
Query Neighborhood Hits	158	Target Neighborhood Hits	271	Shared Neighborhood Hits	12
SwissProt Accessions	P56371	Gene names	Rab4a, Rab4
Domain Architecture
Description	Ras-related protein Rab-4A.

STK10_HUMAN
NC score	0.014110 (rank : 164)	θ value	0.00869519 (rank : 64)
Query Neighborhood Hits	158	Target Neighborhood Hits	1921	Shared Neighborhood Hits	52
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

CE110_HUMAN
NC score	0.013091 (rank : 165)	θ value	6.88961 (rank : 135)
Query Neighborhood Hits	158	Target Neighborhood Hits	197	Shared Neighborhood Hits	19
SwissProt Accessions	O43303, O43335, Q68DV9, Q8NE13	Gene names	CEP110, CP110, KIAA0419
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 110 kDa (Cep110 protein).

LMNB2_MOUSE
NC score	0.012644 (rank : 166)	θ value	6.88961 (rank : 139)
Query Neighborhood Hits	158	Target Neighborhood Hits	674	Shared Neighborhood Hits	29
SwissProt Accessions	P21619, P48680, Q8CGB1	Gene names	Lmnb2
Domain Architecture
Description	Lamin-B2.

TTLL2_HUMAN
NC score	0.012635 (rank : 167)	θ value	5.27518 (rank : 134)
Query Neighborhood Hits	158	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BWV7, Q7Z6R8, Q86X22	Gene names	TTLL2, C6orf104
Domain Architecture
Description	Tubulin--tyrosine ligase-like protein 2 (Testis-specific protein NYD- TSPG).

KI13A_HUMAN
NC score	0.012348 (rank : 168)	θ value	0.813845 (rank : 90)
Query Neighborhood Hits	158	Target Neighborhood Hits	359	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H1H9, Q9H1H8	Gene names	KIF13A, RBKIN
Domain Architecture
Description	Kinesin-like protein KIF13A (Kinesin-like protein RBKIN).

RAB2B_MOUSE
NC score	0.012264 (rank : 169)	θ value	1.81305 (rank : 105)
Query Neighborhood Hits	158	Target Neighborhood Hits	271	Shared Neighborhood Hits	12
SwissProt Accessions	P59279, Q3TV67	Gene names	Rab2b
Domain Architecture
Description	Ras-related protein Rab-2B.

RAB2B_HUMAN
NC score	0.012183 (rank : 170)	θ value	1.81305 (rank : 104)
Query Neighborhood Hits	158	Target Neighborhood Hits	271	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WUD1	Gene names	RAB2B
Domain Architecture
Description	Ras-related protein Rab-2B.

SLK_MOUSE
NC score	0.012118 (rank : 171)	θ value	0.62314 (rank : 87)
Query Neighborhood Hits	158	Target Neighborhood Hits	1798	Shared Neighborhood Hits	53
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

FA48A_HUMAN
NC score	0.011504 (rank : 172)	θ value	5.27518 (rank : 126)
Query Neighborhood Hits	158	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NEM7, Q71RF3, Q9Y6A6	Gene names	FAM48A
Domain Architecture	No domain graphic available
Description	Protein FAM48A (p38-interacting protein) (p38IP).

SLK_HUMAN
NC score	0.011186 (rank : 173)	θ value	1.06291 (rank : 95)
Query Neighborhood Hits	158	Target Neighborhood Hits	1775	Shared Neighborhood Hits	53
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

EXOC6_HUMAN
NC score	0.011046 (rank : 174)	θ value	6.88961 (rank : 137)
Query Neighborhood Hits	158	Target Neighborhood Hits	57	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TAG9, Q9NZ24	Gene names	EXOC6, SEC15A, SEC15L, SEC15L1
Domain Architecture
Description	Exocyst complex component 6 (Exocyst complex component Sec15A) (Sec15- like 1).

GHR_MOUSE
NC score	0.010574 (rank : 175)	θ value	8.99809 (rank : 153)
Query Neighborhood Hits	158	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	P16882, P16590, Q61653, Q6DI66, Q80W86, Q8R1M5, Q920Z3, Q9R264	Gene names	Ghr
Domain Architecture
Description	Growth hormone receptor precursor (GH receptor) (Somatotropin receptor) [Contains: Growth hormone-binding protein (GH-binding protein) (GHBP) (Serum-binding protein)].

K2C4_HUMAN
NC score	0.009620 (rank : 176)	θ value	5.27518 (rank : 128)
Query Neighborhood Hits	158	Target Neighborhood Hits	471	Shared Neighborhood Hits	31
SwissProt Accessions	P19013, Q6GTR8, Q96LA7, Q9BTL1	Gene names	KRT4, CYK4
Domain Architecture
Description	Keratin, type II cytoskeletal 4 (Cytokeratin-4) (CK-4) (Keratin-4) (K4).

BMR1B_HUMAN
NC score	0.009095 (rank : 177)	θ value	0.62314 (rank : 79)
Query Neighborhood Hits	158	Target Neighborhood Hits	760	Shared Neighborhood Hits	9
SwissProt Accessions	O00238, P78366	Gene names	BMPR1B
Domain Architecture
Description	Bone morphogenetic protein receptor type IB precursor (EC 2.7.11.30) (CDw293 antigen).

POLI_HUMAN
NC score	0.009075 (rank : 178)	θ value	5.27518 (rank : 132)
Query Neighborhood Hits	158	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UNA4, Q8N590, Q9H0S1, Q9NYH6	Gene names	POLI, RAD30B
Domain Architecture	No domain graphic available
Description	DNA polymerase iota (EC 2.7.7.7) (RAD30 homolog B) (Eta2).

BMR1B_MOUSE
NC score	0.008957 (rank : 179)	θ value	0.62314 (rank : 80)
Query Neighborhood Hits	158	Target Neighborhood Hits	758	Shared Neighborhood Hits	9
SwissProt Accessions	P36898, Q3TRF2	Gene names	Bmpr1b, Acvrlk6
Domain Architecture
Description	Bone morphogenetic protein receptor type IB precursor (EC 2.7.11.30) (Serine/threonine-protein kinase receptor R6) (SKR6) (Activin receptor-like kinase 6) (ALK-6).

ES8L3_HUMAN
NC score	0.008897 (rank : 180)	θ value	3.0926 (rank : 111)
Query Neighborhood Hits	158	Target Neighborhood Hits	206	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TE67, Q5T8Q6, Q5T8Q7, Q5T8Q8, Q96E47, Q9H719	Gene names	EPS8L3, EPS8R3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

ETV1_HUMAN
NC score	0.008875 (rank : 181)	θ value	5.27518 (rank : 125)
Query Neighborhood Hits	158	Target Neighborhood Hits	107	Shared Neighborhood Hits	4
SwissProt Accessions	P50549, O75849, Q9UQ71, Q9Y636	Gene names	ETV1, ER81
Domain Architecture
Description	ETS translocation variant 1 (ER81 protein).

NOG1_HUMAN
NC score	0.008393 (rank : 182)	θ value	8.99809 (rank : 155)
Query Neighborhood Hits	158	Target Neighborhood Hits	98	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BZE4, O95446, Q9NVJ8	Gene names	GTPBP4, CRFG, NOG1
Domain Architecture
Description	Nucleolar GTP-binding protein 1 (Chronic renal failure gene protein) (GTP-binding protein NGB).

RAB1B_HUMAN
NC score	0.008111 (rank : 183)	θ value	6.88961 (rank : 144)
Query Neighborhood Hits	158	Target Neighborhood Hits	295	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H0U4	Gene names	RAB1B
Domain Architecture
Description	Ras-related protein Rab-1B.

RAB1A_HUMAN
NC score	0.008105 (rank : 184)	θ value	6.88961 (rank : 142)
Query Neighborhood Hits	158	Target Neighborhood Hits	292	Shared Neighborhood Hits	12
SwissProt Accessions	P62820, P11476, Q96N61, Q9Y3T2	Gene names	RAB1A, RAB1
Domain Architecture	No domain graphic available
Description	Ras-related protein Rab-1A (YPT1-related protein).

RAB1A_MOUSE
NC score	0.008105 (rank : 185)	θ value	6.88961 (rank : 143)
Query Neighborhood Hits	158	Target Neighborhood Hits	292	Shared Neighborhood Hits	12
SwissProt Accessions	P62821, P11476, Q3TX44, Q811M4, Q96N61, Q9Y3T2	Gene names	Rab1A, Rab1
Domain Architecture	No domain graphic available
Description	Ras-related protein Rab-1A (YPT1-related protein).

RAB1B_MOUSE
NC score	0.008096 (rank : 186)	θ value	6.88961 (rank : 145)
Query Neighborhood Hits	158	Target Neighborhood Hits	296	Shared Neighborhood Hits	12
SwissProt Accessions	Q9D1G1, Q3U0N1	Gene names	Rab1b
Domain Architecture
Description	Ras-related protein Rab-1B.

ETV1_MOUSE
NC score	0.007942 (rank : 187)	θ value	6.88961 (rank : 136)
Query Neighborhood Hits	158	Target Neighborhood Hits	92	Shared Neighborhood Hits	4
SwissProt Accessions	P41164	Gene names	Etv1, Er81, Etsrp81
Domain Architecture
Description	ETS translocation variant 1 (ER81 protein).

PLXB1_HUMAN
NC score	0.005742 (rank : 188)	θ value	5.27518 (rank : 131)
Query Neighborhood Hits	158	Target Neighborhood Hits	360	Shared Neighborhood Hits	7
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

JHD3B_MOUSE
NC score	0.003023 (rank : 189)	θ value	6.88961 (rank : 138)
Query Neighborhood Hits	158	Target Neighborhood Hits	152	Shared Neighborhood Hits	2
SwissProt Accessions	Q91VY5, Q3UR22, Q6ZQ30, Q99K42	Gene names	Jmjd2b, Jhdm3b
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

1433Z_MOUSE
NC score	0.002814 (rank : 190)	θ value	8.99809 (rank : 146)
Query Neighborhood Hits	158	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	P63101, P35215, P70197, P97286, Q3TSF1, Q5EBQ1	Gene names	Ywhaz
Domain Architecture	No domain graphic available
Description	14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1) (SEZ-2).

PTPRZ_HUMAN
NC score	0.000700 (rank : 191)	θ value	6.88961 (rank : 141)
Query Neighborhood Hits	158	Target Neighborhood Hits	255	Shared Neighborhood Hits	3
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

SSPO_MOUSE
NC score	-0.000884 (rank : 192)	θ value	8.99809 (rank : 157)
Query Neighborhood Hits	158	Target Neighborhood Hits	800	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.