Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : GRLF1_HUMAN

For an explanation of this page, click here

GRLF1_HUMAN
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GRLF1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	167	Target Neighborhood Hits	167	Shared Neighborhood Hits	167
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

RHG05_HUMAN
θ value	0 (rank : 2)	NC score	0.964174 (rank : 3)
Query Neighborhood Hits	167	Target Neighborhood Hits	158	Shared Neighborhood Hits	65
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

RHG05_MOUSE
θ value	0 (rank : 3)	NC score	0.966223 (rank : 2)
Query Neighborhood Hits	167	Target Neighborhood Hits	165	Shared Neighborhood Hits	68
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

CHIO_MOUSE
θ value	8.3442e-30 (rank : 4)	NC score	0.775517 (rank : 8)
Query Neighborhood Hits	167	Target Neighborhood Hits	130	Shared Neighborhood Hits	61
SwissProt Accessions	Q80XD1, Q9D9W2, Q9ER57	Gene names	Chn2, Arhgap3, Bch
Domain Architecture	No domain graphic available
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

CHIN_HUMAN
θ value	7.06379e-29 (rank : 5)	NC score	0.743111 (rank : 19)
Query Neighborhood Hits	167	Target Neighborhood Hits	227	Shared Neighborhood Hits	61
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIO_HUMAN
θ value	7.06379e-29 (rank : 6)	NC score	0.741961 (rank : 21)
Query Neighborhood Hits	167	Target Neighborhood Hits	220	Shared Neighborhood Hits	61
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

CHIN_MOUSE
θ value	9.2256e-29 (rank : 7)	NC score	0.745201 (rank : 18)
Query Neighborhood Hits	167	Target Neighborhood Hits	229	Shared Neighborhood Hits	62
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

RHG12_MOUSE
θ value	2.96777e-27 (rank : 8)	NC score	0.796772 (rank : 6)
Query Neighborhood Hits	167	Target Neighborhood Hits	204	Shared Neighborhood Hits	65
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RHG12_HUMAN
θ value	3.87602e-27 (rank : 9)	NC score	0.799195 (rank : 5)
Query Neighborhood Hits	167	Target Neighborhood Hits	190	Shared Neighborhood Hits	62
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

OPHN1_MOUSE
θ value	2.59989e-23 (rank : 10)	NC score	0.764068 (rank : 14)
Query Neighborhood Hits	167	Target Neighborhood Hits	174	Shared Neighborhood Hits	65
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

OPHN1_HUMAN
θ value	5.79196e-23 (rank : 11)	NC score	0.764751 (rank : 12)
Query Neighborhood Hits	167	Target Neighborhood Hits	161	Shared Neighborhood Hits	64
SwissProt Accessions	O60890, Q5JQ81, Q8WX47	Gene names	OPHN1
Domain Architecture
Description	Oligophrenin 1.

ABR_HUMAN
θ value	1.29031e-22 (rank : 12)	NC score	0.719266 (rank : 27)
Query Neighborhood Hits	167	Target Neighborhood Hits	166	Shared Neighborhood Hits	63
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

RHG26_HUMAN
θ value	2.87452e-22 (rank : 13)	NC score	0.715389 (rank : 28)
Query Neighborhood Hits	167	Target Neighborhood Hits	281	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

RHG09_HUMAN
θ value	8.36355e-22 (rank : 14)	NC score	0.818477 (rank : 4)
Query Neighborhood Hits	167	Target Neighborhood Hits	186	Shared Neighborhood Hits	63
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

MYO9B_MOUSE
θ value	1.09232e-21 (rank : 15)	NC score	0.412280 (rank : 57)
Query Neighborhood Hits	167	Target Neighborhood Hits	311	Shared Neighborhood Hits	67
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

BCR_HUMAN
θ value	1.42661e-21 (rank : 16)	NC score	0.705454 (rank : 30)
Query Neighborhood Hits	167	Target Neighborhood Hits	204	Shared Neighborhood Hits	62
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

SRGP1_HUMAN
θ value	1.86321e-21 (rank : 17)	NC score	0.687666 (rank : 38)
Query Neighborhood Hits	167	Target Neighborhood Hits	390	Shared Neighborhood Hits	66
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

MYO9B_HUMAN
θ value	2.43343e-21 (rank : 18)	NC score	0.406546 (rank : 58)
Query Neighborhood Hits	167	Target Neighborhood Hits	641	Shared Neighborhood Hits	72
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

SRGP2_HUMAN
θ value	9.24701e-21 (rank : 19)	NC score	0.701108 (rank : 31)
Query Neighborhood Hits	167	Target Neighborhood Hits	331	Shared Neighborhood Hits	65
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

CEND2_HUMAN
θ value	1.2077e-20 (rank : 20)	NC score	0.631924 (rank : 46)
Query Neighborhood Hits	167	Target Neighborhood Hits	166	Shared Neighborhood Hits	60
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

SRGP2_MOUSE
θ value	1.74391e-19 (rank : 21)	NC score	0.693616 (rank : 34)
Query Neighborhood Hits	167	Target Neighborhood Hits	324	Shared Neighborhood Hits	65
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

FNBP2_HUMAN
θ value	5.07402e-19 (rank : 22)	NC score	0.681509 (rank : 40)
Query Neighborhood Hits	167	Target Neighborhood Hits	432	Shared Neighborhood Hits	68
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

3BP1_HUMAN
θ value	1.92812e-18 (rank : 23)	NC score	0.768116 (rank : 11)
Query Neighborhood Hits	167	Target Neighborhood Hits	376	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

RBP1_HUMAN
θ value	2.13179e-17 (rank : 24)	NC score	0.688701 (rank : 36)
Query Neighborhood Hits	167	Target Neighborhood Hits	521	Shared Neighborhood Hits	68
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

RHG04_HUMAN
θ value	2.13179e-17 (rank : 25)	NC score	0.710019 (rank : 29)
Query Neighborhood Hits	167	Target Neighborhood Hits	307	Shared Neighborhood Hits	66
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

RBP1_MOUSE
θ value	4.74913e-17 (rank : 26)	NC score	0.701089 (rank : 32)
Query Neighborhood Hits	167	Target Neighborhood Hits	493	Shared Neighborhood Hits	68
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

RHG01_HUMAN
θ value	4.74913e-17 (rank : 27)	NC score	0.749312 (rank : 16)
Query Neighborhood Hits	167	Target Neighborhood Hits	75	Shared Neighborhood Hits	62
SwissProt Accessions	Q07960	Gene names	ARHGAP1, CDC42GAP, RHOGAP1
Domain Architecture
Description	Rho-GTPase-activating protein 1 (GTPase-activating protein rhoOGAP) (Rho-related small GTPase protein activator) (CDC42 GTPase-activating protein) (p50-RhoGAP).

GMIP_MOUSE
θ value	1.38178e-16 (rank : 28)	NC score	0.771649 (rank : 9)
Query Neighborhood Hits	167	Target Neighborhood Hits	202	Shared Neighborhood Hits	65
SwissProt Accessions	Q6PGG2, Q6P9S3	Gene names	Gmip
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

RHG07_MOUSE
θ value	1.80466e-16 (rank : 29)	NC score	0.681892 (rank : 39)
Query Neighborhood Hits	167	Target Neighborhood Hits	103	Shared Neighborhood Hits	63
SwissProt Accessions	Q9R0Z9, Q8R541	Gene names	Dlc1, Arhgap7, Stard12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein homolog) (Dlc-1) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

TCGAP_HUMAN
θ value	1.80466e-16 (rank : 30)	NC score	0.648517 (rank : 43)
Query Neighborhood Hits	167	Target Neighborhood Hits	872	Shared Neighborhood Hits	74
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TCGAP_MOUSE
θ value	1.80466e-16 (rank : 31)	NC score	0.731303 (rank : 22)
Query Neighborhood Hits	167	Target Neighborhood Hits	409	Shared Neighborhood Hits	74
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

CEND3_MOUSE
θ value	4.02038e-16 (rank : 32)	NC score	0.595937 (rank : 51)
Query Neighborhood Hits	167	Target Neighborhood Hits	228	Shared Neighborhood Hits	68
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

STA13_HUMAN
θ value	1.16975e-15 (rank : 33)	NC score	0.641241 (rank : 44)
Query Neighborhood Hits	167	Target Neighborhood Hits	89	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y3M8, Q5HYH1, Q5TAE3, Q6UN61, Q86TP6, Q86WQ3, Q86XT1	Gene names	STARD13, DLC2, GT650
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13) (46H23.2) (Deleted in liver cancer protein 2) (Rho GTPase-activating protein).

3BP1_MOUSE
θ value	1.52774e-15 (rank : 34)	NC score	0.776584 (rank : 7)
Query Neighborhood Hits	167	Target Neighborhood Hits	238	Shared Neighborhood Hits	69
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

RHG07_HUMAN
θ value	1.52774e-15 (rank : 35)	NC score	0.675413 (rank : 41)
Query Neighborhood Hits	167	Target Neighborhood Hits	108	Shared Neighborhood Hits	62
SwissProt Accessions	Q96QB1, O14868, O43199, Q9C0E0	Gene names	DLC1, ARHGAP7, KIAA1723, STARD12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein) (Dlc-1) (HP protein) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

TAGAP_HUMAN
θ value	1.52774e-15 (rank : 36)	NC score	0.700019 (rank : 33)
Query Neighborhood Hits	167	Target Neighborhood Hits	82	Shared Neighborhood Hits	60
SwissProt Accessions	Q8N103, Q2NKM8, Q8NI40, Q96KZ2, Q96QA2	Gene names	TAGAP, TAGAP1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

RHG25_MOUSE
θ value	4.44505e-15 (rank : 37)	NC score	0.693584 (rank : 35)
Query Neighborhood Hits	167	Target Neighborhood Hits	492	Shared Neighborhood Hits	66
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

CEND3_HUMAN
θ value	1.29331e-14 (rank : 38)	NC score	0.583936 (rank : 52)
Query Neighborhood Hits	167	Target Neighborhood Hits	275	Shared Neighborhood Hits	68
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

STA13_MOUSE
θ value	1.68911e-14 (rank : 39)	NC score	0.630036 (rank : 48)
Query Neighborhood Hits	167	Target Neighborhood Hits	89	Shared Neighborhood Hits	58
SwissProt Accessions	Q923Q2, Q8K369	Gene names	Stard13
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13).

STAR8_MOUSE
θ value	2.88119e-14 (rank : 40)	NC score	0.637477 (rank : 45)
Query Neighborhood Hits	167	Target Neighborhood Hits	101	Shared Neighborhood Hits	59
SwissProt Accessions	Q8K031, Q3UZC7, Q6A0A8, Q6P5E0, Q8R3X8	Gene names	Stard8, Kiaa0189
Domain Architecture	No domain graphic available
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

GMIP_HUMAN
θ value	3.76295e-14 (rank : 41)	NC score	0.764403 (rank : 13)
Query Neighborhood Hits	167	Target Neighborhood Hits	225	Shared Neighborhood Hits	67
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

RHG25_HUMAN
θ value	6.41864e-14 (rank : 42)	NC score	0.669745 (rank : 42)
Query Neighborhood Hits	167	Target Neighborhood Hits	550	Shared Neighborhood Hits	67
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

CE005_MOUSE
θ value	8.38298e-14 (rank : 43)	NC score	0.627825 (rank : 50)
Query Neighborhood Hits	167	Target Neighborhood Hits	238	Shared Neighborhood Hits	63
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

CE005_HUMAN
θ value	1.86753e-13 (rank : 44)	NC score	0.628495 (rank : 49)
Query Neighborhood Hits	167	Target Neighborhood Hits	213	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

RGAP1_HUMAN
θ value	1.86753e-13 (rank : 45)	NC score	0.768148 (rank : 10)
Query Neighborhood Hits	167	Target Neighborhood Hits	189	Shared Neighborhood Hits	62
SwissProt Accessions	Q9H0H5, Q6PJ26, Q9NWN2, Q9P250, Q9P2W2	Gene names	RACGAP1, KIAA1478, MGCRACGAP
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RGAP1_MOUSE
θ value	2.43908e-13 (rank : 46)	NC score	0.762676 (rank : 15)
Query Neighborhood Hits	167	Target Neighborhood Hits	185	Shared Neighborhood Hits	62
SwissProt Accessions	Q9WVM1, Q3THR5, Q3TI41, Q3TM81	Gene names	Racgap1, Mgcracgap
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

STAR8_HUMAN
θ value	2.43908e-13 (rank : 47)	NC score	0.630933 (rank : 47)
Query Neighborhood Hits	167	Target Neighborhood Hits	216	Shared Neighborhood Hits	60
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

RHG08_HUMAN
θ value	3.52202e-12 (rank : 48)	NC score	0.721615 (rank : 26)
Query Neighborhood Hits	167	Target Neighborhood Hits	88	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NSG0, O75983, O95695, Q96RW1, Q96RW2, Q9HA49, Q9HC46, Q9NVX8, Q9NXL1, Q9UH20	Gene names	ARHGAP8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RHG06_HUMAN
θ value	1.33837e-11 (rank : 49)	NC score	0.746671 (rank : 17)
Query Neighborhood Hits	167	Target Neighborhood Hits	114	Shared Neighborhood Hits	63
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RHG08_MOUSE
θ value	1.33837e-11 (rank : 50)	NC score	0.723594 (rank : 25)
Query Neighborhood Hits	167	Target Neighborhood Hits	73	Shared Neighborhood Hits	62
SwissProt Accessions	Q9CXP4, Q99JY7	Gene names	Arhgap8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RHG06_MOUSE
θ value	3.89403e-11 (rank : 51)	NC score	0.743083 (rank : 20)
Query Neighborhood Hits	167	Target Neighborhood Hits	105	Shared Neighborhood Hits	62
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RHG18_MOUSE
θ value	3.89403e-11 (rank : 52)	NC score	0.728100 (rank : 24)
Query Neighborhood Hits	167	Target Neighborhood Hits	110	Shared Neighborhood Hits	62
SwissProt Accessions	Q8K0Q5, Q8BP03, Q8R196	Gene names	Arhgap18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18.

RHG18_HUMAN
θ value	1.133e-10 (rank : 53)	NC score	0.729330 (rank : 23)
Query Neighborhood Hits	167	Target Neighborhood Hits	90	Shared Neighborhood Hits	62
SwissProt Accessions	Q8N392, Q58EZ3, Q6P679, Q6PJD7, Q96S64	Gene names	ARHGAP18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18 (MacGAP).

TAGAP_MOUSE
θ value	3.29651e-10 (rank : 54)	NC score	0.688329 (rank : 37)
Query Neighborhood Hits	167	Target Neighborhood Hits	83	Shared Neighborhood Hits	60
SwissProt Accessions	Q8K2L9, Q920D6	Gene names	Tagap, Tagap1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

CEND1_MOUSE
θ value	4.30538e-10 (rank : 55)	NC score	0.531384 (rank : 53)
Query Neighborhood Hits	167	Target Neighborhood Hits	260	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

P85A_HUMAN
θ value	2.13673e-09 (rank : 56)	NC score	0.388942 (rank : 59)
Query Neighborhood Hits	167	Target Neighborhood Hits	479	Shared Neighborhood Hits	63
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

CEND1_HUMAN
θ value	2.79066e-09 (rank : 57)	NC score	0.511332 (rank : 54)
Query Neighborhood Hits	167	Target Neighborhood Hits	284	Shared Neighborhood Hits	66
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

P85A_MOUSE
θ value	8.11959e-09 (rank : 58)	NC score	0.385559 (rank : 60)
Query Neighborhood Hits	167	Target Neighborhood Hits	435	Shared Neighborhood Hits	63
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

K1688_MOUSE
θ value	0.000158464 (rank : 59)	NC score	0.492234 (rank : 55)
Query Neighborhood Hits	167	Target Neighborhood Hits	188	Shared Neighborhood Hits	61
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

K1688_HUMAN
θ value	0.00020696 (rank : 60)	NC score	0.475331 (rank : 56)
Query Neighborhood Hits	167	Target Neighborhood Hits	217	Shared Neighborhood Hits	60
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

I5P2_HUMAN
θ value	0.00035302 (rank : 61)	NC score	0.329099 (rank : 61)
Query Neighborhood Hits	167	Target Neighborhood Hits	86	Shared Neighborhood Hits	52
SwissProt Accessions	P32019, Q5VSG9, Q5VSH0, Q5VSH1, Q658Q5, Q6P6D4, Q6PD53, Q86YE1	Gene names	INPP5B
Domain Architecture	No domain graphic available
Description	Type II inositol-1,4,5-trisphosphate 5-phosphatase precursor (EC 3.1.3.36) (Phosphoinositide 5-phosphatase) (5PTase) (75 kDa inositol polyphosphate-5-phosphatase).

OCRL_HUMAN
θ value	0.0148317 (rank : 62)	NC score	0.313967 (rank : 62)
Query Neighborhood Hits	167	Target Neighborhood Hits	77	Shared Neighborhood Hits	51
SwissProt Accessions	Q01968, O60800, Q15684, Q15774, Q5JQF1, Q5JQF2, Q9UJG5, Q9UMA5	Gene names	OCRL, INPP5F, OCRL1
Domain Architecture
Description	Inositol polyphosphate 5-phosphatase OCRL-1 (EC 3.1.3.36) (Lowe oculocerebrorenal syndrome protein).

RAB3C_HUMAN
θ value	0.0736092 (rank : 63)	NC score	0.047908 (rank : 106)
Query Neighborhood Hits	167	Target Neighborhood Hits	272	Shared Neighborhood Hits	41
SwissProt Accessions	Q96E17	Gene names	RAB3C
Domain Architecture
Description	Ras-related protein Rab-3C.

DIRA2_HUMAN
θ value	0.125558 (rank : 64)	NC score	0.044955 (rank : 124)
Query Neighborhood Hits	167	Target Neighborhood Hits	235	Shared Neighborhood Hits	41
SwissProt Accessions	Q96HU8	Gene names	DIRAS2
Domain Architecture	No domain graphic available
Description	GTP-binding protein Di-Ras2 (Distinct subgroup of the Ras family member 2).

DIRA2_MOUSE
θ value	0.125558 (rank : 65)	NC score	0.047288 (rank : 111)
Query Neighborhood Hits	167	Target Neighborhood Hits	237	Shared Neighborhood Hits	42
SwissProt Accessions	Q5PR73	Gene names	Diras2
Domain Architecture	No domain graphic available
Description	GTP-binding protein Di-Ras2 (Distinct subgroup of the Ras family member 2).

RAB10_HUMAN
θ value	0.125558 (rank : 66)	NC score	0.049377 (rank : 98)
Query Neighborhood Hits	167	Target Neighborhood Hits	278	Shared Neighborhood Hits	42
SwissProt Accessions	P61026, O88386, Q6IA52, Q9D7X6, Q9H0T3	Gene names	RAB10
Domain Architecture
Description	Ras-related protein Rab-10.

RAB10_MOUSE
θ value	0.125558 (rank : 67)	NC score	0.049377 (rank : 99)
Query Neighborhood Hits	167	Target Neighborhood Hits	278	Shared Neighborhood Hits	42
SwissProt Accessions	P61027, O88386, Q9D7X6	Gene names	Rab10
Domain Architecture
Description	Ras-related protein Rab-10.

SPR1A_MOUSE
θ value	0.125558 (rank : 68)	NC score	0.034612 (rank : 139)
Query Neighborhood Hits	167	Target Neighborhood Hits	343	Shared Neighborhood Hits	14
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

DOK1_MOUSE
θ value	0.163984 (rank : 69)	NC score	0.024164 (rank : 143)
Query Neighborhood Hits	167	Target Neighborhood Hits	82	Shared Neighborhood Hits	3
SwissProt Accessions	P97465, Q9R213	Gene names	Dok1, Dok
Domain Architecture
Description	Docking protein 1 (Downstream of tyrosine kinase 1) (p62(dok)).

DSPP_HUMAN
θ value	0.163984 (rank : 70)	NC score	0.018111 (rank : 150)
Query Neighborhood Hits	167	Target Neighborhood Hits	645	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

RAB3C_MOUSE
θ value	0.21417 (rank : 71)	NC score	0.047250 (rank : 112)
Query Neighborhood Hits	167	Target Neighborhood Hits	270	Shared Neighborhood Hits	41
SwissProt Accessions	P62823, Q62858, Q62974, Q63482, Q9CXQ1	Gene names	Rab3c
Domain Architecture	No domain graphic available
Description	Ras-related protein Rab-3C.

S23IP_MOUSE
θ value	0.21417 (rank : 72)	NC score	0.031353 (rank : 141)
Query Neighborhood Hits	167	Target Neighborhood Hits	363	Shared Neighborhood Hits	16
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

ANR15_HUMAN
θ value	0.279714 (rank : 73)	NC score	0.009774 (rank : 167)
Query Neighborhood Hits	167	Target Neighborhood Hits	478	Shared Neighborhood Hits	5
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

RAB13_HUMAN
θ value	0.279714 (rank : 74)	NC score	0.048065 (rank : 104)
Query Neighborhood Hits	167	Target Neighborhood Hits	286	Shared Neighborhood Hits	42
SwissProt Accessions	P51153, Q96GU4	Gene names	RAB13
Domain Architecture
Description	Ras-related protein Rab-13.

RAB13_MOUSE
θ value	0.279714 (rank : 75)	NC score	0.048019 (rank : 105)
Query Neighborhood Hits	167	Target Neighborhood Hits	289	Shared Neighborhood Hits	42
SwissProt Accessions	Q9DD03	Gene names	Rab13
Domain Architecture
Description	Ras-related protein Rab-13.

RAB26_HUMAN
θ value	0.279714 (rank : 76)	NC score	0.048273 (rank : 102)
Query Neighborhood Hits	167	Target Neighborhood Hits	280	Shared Neighborhood Hits	41
SwissProt Accessions	Q9ULW5, Q6NXS7	Gene names	RAB26
Domain Architecture
Description	Ras-related protein Rab-26.

RAB26_MOUSE
θ value	0.279714 (rank : 77)	NC score	0.047694 (rank : 109)
Query Neighborhood Hits	167	Target Neighborhood Hits	287	Shared Neighborhood Hits	41
SwissProt Accessions	Q504M8	Gene names	Rab26
Domain Architecture	No domain graphic available
Description	Ras-related protein Rab-26.

GOGA5_MOUSE
θ value	0.365318 (rank : 78)	NC score	0.012729 (rank : 162)
Query Neighborhood Hits	167	Target Neighborhood Hits	1434	Shared Neighborhood Hits	25
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

RAB15_MOUSE
θ value	0.365318 (rank : 79)	NC score	0.047164 (rank : 113)
Query Neighborhood Hits	167	Target Neighborhood Hits	284	Shared Neighborhood Hits	41
SwissProt Accessions	Q8K386	Gene names	Rab15
Domain Architecture
Description	Ras-related protein Rab-15.

RAB8A_HUMAN
θ value	0.365318 (rank : 80)	NC score	0.048786 (rank : 101)
Query Neighborhood Hits	167	Target Neighborhood Hits	269	Shared Neighborhood Hits	43
SwissProt Accessions	P61006, P24407	Gene names	RAB8A, MEL, RAB8
Domain Architecture
Description	Ras-related protein Rab-8A (Oncogene c-mel).

RAB8A_MOUSE
θ value	0.365318 (rank : 81)	NC score	0.048842 (rank : 100)
Query Neighborhood Hits	167	Target Neighborhood Hits	269	Shared Neighborhood Hits	43
SwissProt Accessions	P55258, Q8VCF6	Gene names	Rab8a, Mel, Rab8
Domain Architecture
Description	Ras-related protein Rab-8A (Oncogene c-mel).

RAB15_HUMAN
θ value	0.47712 (rank : 82)	NC score	0.046825 (rank : 116)
Query Neighborhood Hits	167	Target Neighborhood Hits	283	Shared Neighborhood Hits	41
SwissProt Accessions	P59190, Q86TX7, Q8IW89	Gene names	RAB15
Domain Architecture
Description	Ras-related protein Rab-15.

RAB37_MOUSE
θ value	0.47712 (rank : 83)	NC score	0.047132 (rank : 114)
Query Neighborhood Hits	167	Target Neighborhood Hits	271	Shared Neighborhood Hits	41
SwissProt Accessions	Q9JKM7, Q8C7E1	Gene names	Rab37
Domain Architecture
Description	Ras-related protein Rab-37.

RAB7_HUMAN
θ value	0.47712 (rank : 84)	NC score	0.043815 (rank : 127)
Query Neighborhood Hits	167	Target Neighborhood Hits	274	Shared Neighborhood Hits	41
SwissProt Accessions	P51149, Q9UPB0	Gene names	RAB7
Domain Architecture
Description	Ras-related protein Rab-7.

RAB7_MOUSE
θ value	0.47712 (rank : 85)	NC score	0.043815 (rank : 128)
Query Neighborhood Hits	167	Target Neighborhood Hits	274	Shared Neighborhood Hits	41
SwissProt Accessions	P51150	Gene names	Rab7
Domain Architecture
Description	Ras-related protein Rab-7.

RASN_HUMAN
θ value	0.47712 (rank : 86)	NC score	0.043470 (rank : 129)
Query Neighborhood Hits	167	Target Neighborhood Hits	259	Shared Neighborhood Hits	42
SwissProt Accessions	P01111, Q14971, Q15104, Q15282	Gene names	NRAS
Domain Architecture
Description	GTPase NRas precursor (Transforming protein N-Ras).

RAB35_HUMAN
θ value	0.62314 (rank : 87)	NC score	0.045497 (rank : 122)
Query Neighborhood Hits	167	Target Neighborhood Hits	287	Shared Neighborhood Hits	41
SwissProt Accessions	Q15286	Gene names	RAB35, RAB1C, RAY
Domain Architecture
Description	Ras-related protein Rab-35 (Rab-1C) (GTP-binding protein RAY).

RAB35_MOUSE
θ value	0.62314 (rank : 88)	NC score	0.045497 (rank : 123)
Query Neighborhood Hits	167	Target Neighborhood Hits	287	Shared Neighborhood Hits	41
SwissProt Accessions	Q6PHN9	Gene names	Rab35
Domain Architecture	No domain graphic available
Description	Ras-related protein Rab-35.

RASN_MOUSE
θ value	0.62314 (rank : 89)	NC score	0.043193 (rank : 130)
Query Neighborhood Hits	167	Target Neighborhood Hits	258	Shared Neighborhood Hits	42
SwissProt Accessions	P08556	Gene names	Nras
Domain Architecture
Description	GTPase NRas precursor (Transforming protein N-Ras).

K1802_HUMAN
θ value	0.813845 (rank : 90)	NC score	0.018678 (rank : 149)
Query Neighborhood Hits	167	Target Neighborhood Hits	1378	Shared Neighborhood Hits	32
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

RAB17_MOUSE
θ value	0.813845 (rank : 91)	NC score	0.042148 (rank : 131)
Query Neighborhood Hits	167	Target Neighborhood Hits	277	Shared Neighborhood Hits	40
SwissProt Accessions	P35292, Q921D2, Q9D723	Gene names	Rab17
Domain Architecture
Description	Ras-related protein Rab-17.

RAB37_HUMAN
θ value	0.813845 (rank : 92)	NC score	0.046577 (rank : 118)
Query Neighborhood Hits	167	Target Neighborhood Hits	271	Shared Neighborhood Hits	41
SwissProt Accessions	Q96AX2	Gene names	RAB37
Domain Architecture
Description	Ras-related protein Rab-37.

SPR1B_HUMAN
θ value	0.813845 (rank : 93)	NC score	0.036444 (rank : 138)
Query Neighborhood Hits	167	Target Neighborhood Hits	102	Shared Neighborhood Hits	6
SwissProt Accessions	P22528, P22529, P22530, Q5T524	Gene names	SPRR1B
Domain Architecture	No domain graphic available
Description	Cornifin B (Small proline-rich protein IB) (SPR-IB) (14.9 kDa pancornulin).

SAPS1_HUMAN
θ value	1.06291 (rank : 94)	NC score	0.020021 (rank : 145)
Query Neighborhood Hits	167	Target Neighborhood Hits	704	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

SPR1A_HUMAN
θ value	1.06291 (rank : 95)	NC score	0.033313 (rank : 140)
Query Neighborhood Hits	167	Target Neighborhood Hits	136	Shared Neighborhood Hits	7
SwissProt Accessions	P35321, Q9UDG4	Gene names	SPRR1A
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein IA) (SPR-IA) (SPRK) (19 kDa pancornulin).

SPR1B_MOUSE
θ value	1.06291 (rank : 96)	NC score	0.030339 (rank : 142)
Query Neighborhood Hits	167	Target Neighborhood Hits	395	Shared Neighborhood Hits	16
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

RAB8B_HUMAN
θ value	1.38821 (rank : 97)	NC score	0.046922 (rank : 115)
Query Neighborhood Hits	167	Target Neighborhood Hits	275	Shared Neighborhood Hits	42
SwissProt Accessions	Q92930, Q9P293	Gene names	RAB8B
Domain Architecture
Description	Ras-related protein Rab-8B.

RAB8B_MOUSE
θ value	1.38821 (rank : 98)	NC score	0.046820 (rank : 117)
Query Neighborhood Hits	167	Target Neighborhood Hits	277	Shared Neighborhood Hits	42
SwissProt Accessions	P61028, Q3U1Z3	Gene names	Rab8b
Domain Architecture
Description	Ras-related protein Rab-8B.

CCD46_MOUSE
θ value	1.81305 (rank : 99)	NC score	0.012988 (rank : 161)
Query Neighborhood Hits	167	Target Neighborhood Hits	1405	Shared Neighborhood Hits	30
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

K1802_MOUSE
θ value	1.81305 (rank : 100)	NC score	0.013439 (rank : 160)
Query Neighborhood Hits	167	Target Neighborhood Hits	1596	Shared Neighborhood Hits	27
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

RAB38_HUMAN
θ value	1.81305 (rank : 101)	NC score	0.047656 (rank : 110)
Query Neighborhood Hits	167	Target Neighborhood Hits	255	Shared Neighborhood Hits	42
SwissProt Accessions	P57729, Q53XK7	Gene names	RAB38
Domain Architecture
Description	Ras-related protein Rab-38 (Antigen NY-MEL-1).

RASE_MOUSE
θ value	1.81305 (rank : 102)	NC score	0.041676 (rank : 132)
Query Neighborhood Hits	167	Target Neighborhood Hits	209	Shared Neighborhood Hits	40
SwissProt Accessions	Q7TN89	Gene names	Eras
Domain Architecture	No domain graphic available
Description	GTPase ERas precursor (E-Ras) (Embryonic stem cell-expressed Ras).

RB27B_HUMAN
θ value	1.81305 (rank : 103)	NC score	0.045685 (rank : 121)
Query Neighborhood Hits	167	Target Neighborhood Hits	281	Shared Neighborhood Hits	41
SwissProt Accessions	O00194, Q9BZB6	Gene names	RAB27B
Domain Architecture
Description	Ras-related protein Rab-27B (C25KG).

RB27B_MOUSE
θ value	1.81305 (rank : 104)	NC score	0.045708 (rank : 120)
Query Neighborhood Hits	167	Target Neighborhood Hits	276	Shared Neighborhood Hits	41
SwissProt Accessions	Q99P58, Q8CIX0	Gene names	Rab27b
Domain Architecture
Description	Ras-related protein Rab-27B.

RIPK3_MOUSE
θ value	1.81305 (rank : 105)	NC score	-0.003809 (rank : 201)
Query Neighborhood Hits	167	Target Neighborhood Hits	867	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QZL0	Gene names	Ripk3, Rip3
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (mRIP3).

SON_HUMAN
θ value	1.81305 (rank : 106)	NC score	0.016458 (rank : 156)
Query Neighborhood Hits	167	Target Neighborhood Hits	1568	Shared Neighborhood Hits	32
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

SYNC_HUMAN
θ value	1.81305 (rank : 107)	NC score	0.014133 (rank : 158)
Query Neighborhood Hits	167	Target Neighborhood Hits	47	Shared Neighborhood Hits	2
SwissProt Accessions	O43776	Gene names	NARS, ASNS
Domain Architecture
Description	Asparaginyl-tRNA synthetase, cytoplasmic (EC 6.1.1.22) (Asparagine-- tRNA ligase) (AsnRS).

T2EA_MOUSE
θ value	1.81305 (rank : 108)	NC score	0.019495 (rank : 148)
Query Neighborhood Hits	167	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D0D5, Q544T0	Gene names	Gtf2e1
Domain Architecture
Description	Transcription initiation factor IIE subunit alpha (TFIIE-alpha) (General transcription factor IIE 56 kDa subunit).

CHD2_HUMAN
θ value	2.36792 (rank : 109)	NC score	0.008456 (rank : 175)
Query Neighborhood Hits	167	Target Neighborhood Hits	360	Shared Neighborhood Hits	10
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

RAB38_MOUSE
θ value	2.36792 (rank : 110)	NC score	0.046161 (rank : 119)
Query Neighborhood Hits	167	Target Neighborhood Hits	256	Shared Neighborhood Hits	41
SwissProt Accessions	Q8QZZ8, Q9D7E8	Gene names	Rab38
Domain Architecture
Description	Ras-related protein Rab-38.

RB39B_HUMAN
θ value	2.36792 (rank : 111)	NC score	0.044573 (rank : 126)
Query Neighborhood Hits	167	Target Neighborhood Hits	279	Shared Neighborhood Hits	43
SwissProt Accessions	Q96DA2, Q5JT79, Q8NEX3	Gene names	RAB39B
Domain Architecture
Description	Ras-related protein Rab-39B.

RB39B_MOUSE
θ value	2.36792 (rank : 112)	NC score	0.044594 (rank : 125)
Query Neighborhood Hits	167	Target Neighborhood Hits	277	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BHC1, Q3TUJ3	Gene names	Rab39b
Domain Architecture
Description	Ras-related protein Rab-39B.

SPT5H_HUMAN
θ value	2.36792 (rank : 113)	NC score	0.019853 (rank : 147)
Query Neighborhood Hits	167	Target Neighborhood Hits	436	Shared Neighborhood Hits	15
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

SPT5H_MOUSE
θ value	2.36792 (rank : 114)	NC score	0.019873 (rank : 146)
Query Neighborhood Hits	167	Target Neighborhood Hits	437	Shared Neighborhood Hits	15
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

TAF9_HUMAN
θ value	2.36792 (rank : 115)	NC score	0.014112 (rank : 159)
Query Neighborhood Hits	167	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	Q16594, Q9BTS1	Gene names	TAF9, TAF2G, TAFII31
Domain Architecture
Description	Transcription initiation factor TFIID subunit 9 (Transcription initiation factor TFIID 31 kDa subunit) (TAFII-31) (TAFII-32) (TAFII32) (STAF31/32).

ATX7_MOUSE
θ value	3.0926 (rank : 116)	NC score	0.016529 (rank : 155)
Query Neighborhood Hits	167	Target Neighborhood Hits	328	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

CP4FB_HUMAN
θ value	3.0926 (rank : 117)	NC score	0.001977 (rank : 195)
Query Neighborhood Hits	167	Target Neighborhood Hits	114	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HBI6, O75254, Q96AQ5	Gene names	CYP4F11
Domain Architecture
Description	Cytochrome P450 4F11 (EC 1.14.14.1) (CYPIVF11).

GTSE1_MOUSE
θ value	3.0926 (rank : 118)	NC score	0.017837 (rank : 153)
Query Neighborhood Hits	167	Target Neighborhood Hits	245	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R080, O89015, Q9CSG9	Gene names	Gtse1, B99
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (Gtse-1) (B99 protein).

K1543_HUMAN
θ value	3.0926 (rank : 119)	NC score	0.017915 (rank : 152)
Query Neighborhood Hits	167	Target Neighborhood Hits	435	Shared Neighborhood Hits	13
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

MKL1_MOUSE
θ value	3.0926 (rank : 120)	NC score	0.017964 (rank : 151)
Query Neighborhood Hits	167	Target Neighborhood Hits	667	Shared Neighborhood Hits	16
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

RALB_HUMAN
θ value	3.0926 (rank : 121)	NC score	0.039001 (rank : 136)
Query Neighborhood Hits	167	Target Neighborhood Hits	274	Shared Neighborhood Hits	41
SwissProt Accessions	P11234	Gene names	RALB
Domain Architecture
Description	Ras-related protein Ral-B.

SSBP4_HUMAN
θ value	3.0926 (rank : 122)	NC score	0.011750 (rank : 165)
Query Neighborhood Hits	167	Target Neighborhood Hits	753	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

HSF1_MOUSE
θ value	4.03905 (rank : 123)	NC score	0.021544 (rank : 144)
Query Neighborhood Hits	167	Target Neighborhood Hits	267	Shared Neighborhood Hits	13
SwissProt Accessions	P38532, O70462	Gene names	Hsf1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

NR4A2_HUMAN
θ value	4.03905 (rank : 124)	NC score	0.003187 (rank : 192)
Query Neighborhood Hits	167	Target Neighborhood Hits	120	Shared Neighborhood Hits	3
SwissProt Accessions	P43354, Q16311	Gene names	NR4A2, NOT, NURR1, TINUR
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (Immediate-early response protein NOT) (Transcriptionally-inducible nuclear receptor).

NR4A2_MOUSE
θ value	4.03905 (rank : 125)	NC score	0.003189 (rank : 191)
Query Neighborhood Hits	167	Target Neighborhood Hits	121	Shared Neighborhood Hits	3
SwissProt Accessions	Q06219, O08690	Gene names	Nr4a2, Nurr1
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (NUR- related factor 1).

CP135_HUMAN
θ value	5.27518 (rank : 126)	NC score	0.004710 (rank : 183)
Query Neighborhood Hits	167	Target Neighborhood Hits	1290	Shared Neighborhood Hits	22
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

DIRA1_MOUSE
θ value	5.27518 (rank : 127)	NC score	0.048175 (rank : 103)
Query Neighborhood Hits	167	Target Neighborhood Hits	233	Shared Neighborhood Hits	42
SwissProt Accessions	Q91Z61	Gene names	Diras1, Gbts1
Domain Architecture	No domain graphic available
Description	GTP-binding protein Di-Ras1 (Distinct subgroup of the Ras family member 1) (Small GTP-binding tumor suppressor 1).

KIF3B_HUMAN
θ value	5.27518 (rank : 128)	NC score	0.003277 (rank : 189)
Query Neighborhood Hits	167	Target Neighborhood Hits	540	Shared Neighborhood Hits	12
SwissProt Accessions	O15066	Gene names	KIF3B, KIAA0359
Domain Architecture
Description	Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B) (HH0048).

PTN13_HUMAN
θ value	5.27518 (rank : 129)	NC score	0.001497 (rank : 198)
Query Neighborhood Hits	167	Target Neighborhood Hits	471	Shared Neighborhood Hits	13
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

RAB4B_HUMAN
θ value	5.27518 (rank : 130)	NC score	0.047861 (rank : 108)
Query Neighborhood Hits	167	Target Neighborhood Hits	283	Shared Neighborhood Hits	43
SwissProt Accessions	P61018, P22750, Q7Z514, Q9HBR6	Gene names	RAB4B
Domain Architecture
Description	Ras-related protein Rab-4B.

RAB4B_MOUSE
θ value	5.27518 (rank : 131)	NC score	0.047862 (rank : 107)
Query Neighborhood Hits	167	Target Neighborhood Hits	283	Shared Neighborhood Hits	43
SwissProt Accessions	Q91ZR1	Gene names	Rab4b, Rab4
Domain Architecture
Description	Ras-related protein Rab-4B.

RASE_HUMAN
θ value	5.27518 (rank : 132)	NC score	0.041046 (rank : 133)
Query Neighborhood Hits	167	Target Neighborhood Hits	214	Shared Neighborhood Hits	41
SwissProt Accessions	Q7Z444	Gene names	ERAS, HRAS2, HRASP
Domain Architecture	No domain graphic available
Description	GTPase ERas precursor (E-Ras) (Embryonic stem cell-expressed Ras).

RPGR1_HUMAN
θ value	5.27518 (rank : 133)	NC score	0.008634 (rank : 174)
Query Neighborhood Hits	167	Target Neighborhood Hits	578	Shared Neighborhood Hits	13
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

SAPS2_MOUSE
θ value	5.27518 (rank : 134)	NC score	0.011557 (rank : 166)
Query Neighborhood Hits	167	Target Neighborhood Hits	47	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R3Q2, Q9CXB7	Gene names	Saps2, Kiaa0685
Domain Architecture
Description	SAPS domain family member 2.

SLIK3_HUMAN
θ value	5.27518 (rank : 135)	NC score	0.001613 (rank : 197)
Query Neighborhood Hits	167	Target Neighborhood Hits	298	Shared Neighborhood Hits	7
SwissProt Accessions	O94933	Gene names	SLITRK3, KIAA0848
Domain Architecture	No domain graphic available
Description	SLIT and NTRK-like protein 3 precursor.

TEAD1_MOUSE
θ value	5.27518 (rank : 136)	NC score	0.005808 (rank : 180)
Query Neighborhood Hits	167	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	P30051	Gene names	Tead1, Tcf13, Tef-1, Tef1
Domain Architecture
Description	Transcriptional enhancer factor TEF-1 (TEA domain family member 1) (TEAD-1) (Protein GT-IIC) (Transcription factor 13) (NTEF-1).

TM108_MOUSE
θ value	5.27518 (rank : 137)	NC score	0.012382 (rank : 163)
Query Neighborhood Hits	167	Target Neighborhood Hits	336	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

ANTR1_HUMAN
θ value	6.88961 (rank : 138)	NC score	0.009226 (rank : 171)
Query Neighborhood Hits	167	Target Neighborhood Hits	128	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H6X2, Q96P02, Q9NVP3	Gene names	ANTXR1, ATR, TEM8
Domain Architecture
Description	Anthrax toxin receptor 1 precursor (Tumor endothelial marker 8).

CI093_HUMAN
θ value	6.88961 (rank : 139)	NC score	0.014485 (rank : 157)
Query Neighborhood Hits	167	Target Neighborhood Hits	1088	Shared Neighborhood Hits	23
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

DPOLZ_HUMAN
θ value	6.88961 (rank : 140)	NC score	0.009260 (rank : 169)
Query Neighborhood Hits	167	Target Neighborhood Hits	200	Shared Neighborhood Hits	7
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

DTNA_HUMAN
θ value	6.88961 (rank : 141)	NC score	0.007697 (rank : 178)
Query Neighborhood Hits	167	Target Neighborhood Hits	295	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y4J8, O15332, O15333, O75697, Q13197, Q13198, Q13199, Q13498, Q13499, Q13500	Gene names	DTNA, DRP3
Domain Architecture
Description	Dystrobrevin alpha (Dystrobrevin-alpha) (Dystrophin-related protein 3).

DTNA_MOUSE
θ value	6.88961 (rank : 142)	NC score	0.008644 (rank : 173)
Query Neighborhood Hits	167	Target Neighborhood Hits	264	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D2N4, P97319, Q61498, Q61499, Q9QZZ5, Q9WUL9, Q9WUM0	Gene names	Dtna, Dtn
Domain Architecture
Description	Dystrobrevin alpha (Alpha-dystrobrevin).

ILRL2_MOUSE
θ value	6.88961 (rank : 143)	NC score	0.003300 (rank : 188)
Query Neighborhood Hits	167	Target Neighborhood Hits	158	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ERS7	Gene names	Il1rl2
Domain Architecture
Description	Interleukin-1 receptor-like 2 precursor (IL-1Rrp2).

IQGA2_HUMAN
θ value	6.88961 (rank : 144)	NC score	0.012352 (rank : 164)
Query Neighborhood Hits	167	Target Neighborhood Hits	200	Shared Neighborhood Hits	6
SwissProt Accessions	Q13576	Gene names	IQGAP2
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP2.

KI18A_MOUSE
θ value	6.88961 (rank : 145)	NC score	0.002708 (rank : 194)
Query Neighborhood Hits	167	Target Neighborhood Hits	212	Shared Neighborhood Hits	7
SwissProt Accessions	Q91WD7, Q3TP77, Q8BLL1	Gene names	Kif18a
Domain Architecture	No domain graphic available
Description	Kinesin family member 18A.

KIF3B_MOUSE
θ value	6.88961 (rank : 146)	NC score	0.002974 (rank : 193)
Query Neighborhood Hits	167	Target Neighborhood Hits	533	Shared Neighborhood Hits	14
SwissProt Accessions	Q61771	Gene names	Kif3b
Domain Architecture
Description	Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B).

MAGE1_HUMAN
θ value	6.88961 (rank : 147)	NC score	0.009040 (rank : 172)
Query Neighborhood Hits	167	Target Neighborhood Hits	1389	Shared Neighborhood Hits	28
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

NOL11_MOUSE
θ value	6.88961 (rank : 148)	NC score	0.009378 (rank : 168)
Query Neighborhood Hits	167	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BJW5, Q8BGJ1, Q8R3Q3, Q99KA5	Gene names	Nol11
Domain Architecture	No domain graphic available
Description	Nucleolar protein 11.

RALB_MOUSE
θ value	6.88961 (rank : 149)	NC score	0.038237 (rank : 137)
Query Neighborhood Hits	167	Target Neighborhood Hits	274	Shared Neighborhood Hits	41
SwissProt Accessions	Q9JIW9, Q3TVS5	Gene names	Ralb
Domain Architecture
Description	Ras-related protein Ral-B.

RASH_HUMAN
θ value	6.88961 (rank : 150)	NC score	0.040168 (rank : 135)
Query Neighborhood Hits	167	Target Neighborhood Hits	263	Shared Neighborhood Hits	41
SwissProt Accessions	P01112, Q14080, Q6FHV9	Gene names	HRAS, HRAS1
Domain Architecture
Description	GTPase HRas precursor (Transforming protein p21) (p21ras) (H-Ras-1) (c-H-ras).

RASH_MOUSE
θ value	6.88961 (rank : 151)	NC score	0.040236 (rank : 134)
Query Neighborhood Hits	167	Target Neighborhood Hits	257	Shared Neighborhood Hits	41
SwissProt Accessions	Q61411, Q80WD2	Gene names	Hras1, Hras
Domain Architecture
Description	GTPase HRas precursor (Transforming protein p21) (p21ras) (H-Ras-1) (c-H-ras).

RBCC1_MOUSE
θ value	6.88961 (rank : 152)	NC score	0.005799 (rank : 181)
Query Neighborhood Hits	167	Target Neighborhood Hits	1048	Shared Neighborhood Hits	16
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

RBP2_HUMAN
θ value	6.88961 (rank : 153)	NC score	0.004189 (rank : 184)
Query Neighborhood Hits	167	Target Neighborhood Hits	249	Shared Neighborhood Hits	9
SwissProt Accessions	P49792, Q13074, Q15280, Q53TE2, Q59FH7	Gene names	RANBP2, NUP358
Domain Architecture
Description	Ran-binding protein 2 (RanBP2) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (358 kDa nucleoporin) (P270).

SRBP1_MOUSE
θ value	6.88961 (rank : 154)	NC score	0.009251 (rank : 170)
Query Neighborhood Hits	167	Target Neighborhood Hits	384	Shared Neighborhood Hits	13
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

UACA_HUMAN
θ value	6.88961 (rank : 155)	NC score	0.003258 (rank : 190)
Query Neighborhood Hits	167	Target Neighborhood Hits	1622	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

ADA12_MOUSE
θ value	8.99809 (rank : 156)	NC score	0.001656 (rank : 196)
Query Neighborhood Hits	167	Target Neighborhood Hits	474	Shared Neighborhood Hits	14
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

DC1L1_HUMAN
θ value	8.99809 (rank : 157)	NC score	0.008438 (rank : 176)
Query Neighborhood Hits	167	Target Neighborhood Hits	39	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y6G9, Q53HC8, Q53HK7	Gene names	DYNC1LI1, DNCLI1
Domain Architecture	No domain graphic available
Description	Cytoplasmic dynein 1 light intermediate chain 1 (Dynein light intermediate chain 1, cytosolic) (Dynein light chain A) (DLC-A).

DC1L1_MOUSE
θ value	8.99809 (rank : 158)	NC score	0.008272 (rank : 177)
Query Neighborhood Hits	167	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R1Q8	Gene names	Dync1li1, Dncli1, Dnclic1
Domain Architecture	No domain graphic available
Description	Cytoplasmic dynein 1 light intermediate chain 1 (Dynein light intermediate chain 1, cytosolic) (Dynein light chain A) (DLC-A).

EVI1_MOUSE
θ value	8.99809 (rank : 159)	NC score	-0.006036 (rank : 202)
Query Neighborhood Hits	167	Target Neighborhood Hits	826	Shared Neighborhood Hits	6
SwissProt Accessions	P14404	Gene names	Evi1, Evi-1
Domain Architecture	No domain graphic available
Description	Ecotropic virus integration 1 site protein.

MUCDL_HUMAN
θ value	8.99809 (rank : 160)	NC score	0.004911 (rank : 182)
Query Neighborhood Hits	167	Target Neighborhood Hits	777	Shared Neighborhood Hits	21
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

NALD2_HUMAN
θ value	8.99809 (rank : 161)	NC score	0.003536 (rank : 187)
Query Neighborhood Hits	167	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y3Q0	Gene names	NAALAD2
Domain Architecture
Description	N-acetylated-alpha-linked acidic dipeptidase 2 (EC 3.4.17.21) (N- acetylated-alpha-linked acidic dipeptidase II) (NAALADase II).

PGS1_HUMAN
θ value	8.99809 (rank : 162)	NC score	-0.000270 (rank : 199)
Query Neighborhood Hits	167	Target Neighborhood Hits	261	Shared Neighborhood Hits	4
SwissProt Accessions	P21810, P13247	Gene names	BGN
Domain Architecture
Description	Biglycan precursor (Bone/cartilage proteoglycan I) (PG-S1).

PGS1_MOUSE
θ value	8.99809 (rank : 163)	NC score	-0.000313 (rank : 200)
Query Neighborhood Hits	167	Target Neighborhood Hits	265	Shared Neighborhood Hits	4
SwissProt Accessions	P28653, Q61355	Gene names	Bgn
Domain Architecture
Description	Biglycan precursor (Bone/cartilage proteoglycan I) (PG-S1).

PTPRN_MOUSE
θ value	8.99809 (rank : 164)	NC score	0.003783 (rank : 186)
Query Neighborhood Hits	167	Target Neighborhood Hits	240	Shared Neighborhood Hits	9
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

RGS3_MOUSE
θ value	8.99809 (rank : 165)	NC score	0.017255 (rank : 154)
Query Neighborhood Hits	167	Target Neighborhood Hits	1621	Shared Neighborhood Hits	34
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

RPGF6_HUMAN
θ value	8.99809 (rank : 166)	NC score	0.004132 (rank : 185)
Query Neighborhood Hits	167	Target Neighborhood Hits	266	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

TAF1C_MOUSE
θ value	8.99809 (rank : 167)	NC score	0.007224 (rank : 179)
Query Neighborhood Hits	167	Target Neighborhood Hits	54	Shared Neighborhood Hits	2
SwissProt Accessions	Q6PDZ2, P97359, Q3U3B6, Q8BN54	Gene names	Taf1c
Domain Architecture	No domain graphic available
Description	TATA box-binding protein-associated factor, RNA polymerase I, subunit C (TATA box-binding protein-associated factor 1C) (TBP-associated factor 1C) (TBP-associated factor RNA polymerase I 95 kDa) (TAFI95).

CENA2_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.051554 (rank : 90)
Query Neighborhood Hits	167	Target Neighborhood Hits	83	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

CENB1_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.071985 (rank : 70)
Query Neighborhood Hits	167	Target Neighborhood Hits	383	Shared Neighborhood Hits	13
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

CENB2_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.077767 (rank : 64)
Query Neighborhood Hits	167	Target Neighborhood Hits	425	Shared Neighborhood Hits	15
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

CENB5_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.073808 (rank : 68)
Query Neighborhood Hits	167	Target Neighborhood Hits	395	Shared Neighborhood Hits	13
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

CENG1_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.052730 (rank : 85)
Query Neighborhood Hits	167	Target Neighborhood Hits	544	Shared Neighborhood Hits	44
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

CENG1_MOUSE
θ value	θ > 10 (rank : 173)	NC score	0.052194 (rank : 88)
Query Neighborhood Hits	167	Target Neighborhood Hits	531	Shared Neighborhood Hits	35
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

CIP4_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.056096 (rank : 77)
Query Neighborhood Hits	167	Target Neighborhood Hits	374	Shared Neighborhood Hits	14
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

DAPP1_MOUSE
θ value	θ > 10 (rank : 175)	NC score	0.050217 (rank : 97)
Query Neighborhood Hits	167	Target Neighborhood Hits	225	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DDEF2_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.055825 (rank : 78)
Query Neighborhood Hits	167	Target Neighborhood Hits	599	Shared Neighborhood Hits	26
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
θ value	θ > 10 (rank : 177)	NC score	0.054177 (rank : 81)
Query Neighborhood Hits	167	Target Neighborhood Hits	625	Shared Neighborhood Hits	26
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDFL1_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.051034 (rank : 95)
Query Neighborhood Hits	167	Target Neighborhood Hits	353	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

FA13A_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.065870 (rank : 73)
Query Neighborhood Hits	167	Target Neighborhood Hits	102	Shared Neighborhood Hits	6
SwissProt Accessions	O94988, Q8NBA3	Gene names	FAM13A1, KIAA0914
Domain Architecture	No domain graphic available
Description	Protein FAM13A1.

FA13A_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.065370 (rank : 74)
Query Neighborhood Hits	167	Target Neighborhood Hits	83	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BGI4, Q8BZ91	Gene names	Fam13a1, Precm1
Domain Architecture	No domain graphic available
Description	Protein FAM13A1 (Precm1 protein).

FA13C_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.051460 (rank : 92)
Query Neighborhood Hits	167	Target Neighborhood Hits	94	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NE31, Q99787	Gene names	FAM13C1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

GRAP_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.054047 (rank : 82)
Query Neighborhood Hits	167	Target Neighborhood Hits	307	Shared Neighborhood Hits	13
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

GRAP_MOUSE
θ value	θ > 10 (rank : 183)	NC score	0.051279 (rank : 93)
Query Neighborhood Hits	167	Target Neighborhood Hits	309	Shared Neighborhood Hits	13
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

GRB2_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.052547 (rank : 86)
Query Neighborhood Hits	167	Target Neighborhood Hits	310	Shared Neighborhood Hits	13
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
θ value	θ > 10 (rank : 185)	NC score	0.052539 (rank : 87)
Query Neighborhood Hits	167	Target Neighborhood Hits	312	Shared Neighborhood Hits	13
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

GRP3_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.077246 (rank : 65)
Query Neighborhood Hits	167	Target Neighborhood Hits	131	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IV61, O94931	Gene names	RASGRP3, GRP3, KIAA0846
Domain Architecture
Description	RAS guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1).

NCK2_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.059812 (rank : 75)
Query Neighborhood Hits	167	Target Neighborhood Hits	310	Shared Neighborhood Hits	15
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

P55G_HUMAN
θ value	θ > 10 (rank : 188)	NC score	0.056331 (rank : 76)
Query Neighborhood Hits	167	Target Neighborhood Hits	451	Shared Neighborhood Hits	12
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

P55G_MOUSE
θ value	θ > 10 (rank : 189)	NC score	0.055100 (rank : 80)
Query Neighborhood Hits	167	Target Neighborhood Hits	401	Shared Neighborhood Hits	10
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

P85B_HUMAN
θ value	θ > 10 (rank : 190)	NC score	0.100997 (rank : 63)
Query Neighborhood Hits	167	Target Neighborhood Hits	543	Shared Neighborhood Hits	30
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

P85B_MOUSE
θ value	θ > 10 (rank : 191)	NC score	0.072635 (rank : 69)
Query Neighborhood Hits	167	Target Neighborhood Hits	519	Shared Neighborhood Hits	26
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

PCTL_HUMAN
θ value	θ > 10 (rank : 192)	NC score	0.067654 (rank : 72)
Query Neighborhood Hits	167	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y365, O60532	Gene names	STARD10, SDCCAG28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28) (Antigen NY-CO-28).

PCTL_MOUSE
θ value	θ > 10 (rank : 193)	NC score	0.068436 (rank : 71)
Query Neighborhood Hits	167	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JMD3	Gene names	Stard10, Pctpl, Sdccag28, Sdccagg28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28 homolog).

PDZD8_HUMAN
θ value	θ > 10 (rank : 194)	NC score	0.055600 (rank : 79)
Query Neighborhood Hits	167	Target Neighborhood Hits	185	Shared Neighborhood Hits	12
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

PRP40_HUMAN
θ value	θ > 10 (rank : 195)	NC score	0.052001 (rank : 89)
Query Neighborhood Hits	167	Target Neighborhood Hits	442	Shared Neighborhood Hits	14
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

SMP1L_HUMAN
θ value	θ > 10 (rank : 196)	NC score	0.051479 (rank : 91)
Query Neighborhood Hits	167	Target Neighborhood Hits	74	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

SMP1L_MOUSE
θ value	θ > 10 (rank : 197)	NC score	0.051195 (rank : 94)
Query Neighborhood Hits	167	Target Neighborhood Hits	70	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

TCRG1_HUMAN
θ value	θ > 10 (rank : 198)	NC score	0.076337 (rank : 67)
Query Neighborhood Hits	167	Target Neighborhood Hits	929	Shared Neighborhood Hits	27
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TCRG1_MOUSE
θ value	θ > 10 (rank : 199)	NC score	0.076617 (rank : 66)
Query Neighborhood Hits	167	Target Neighborhood Hits	947	Shared Neighborhood Hits	28
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

VAV3_HUMAN
θ value	θ > 10 (rank : 200)	NC score	0.053720 (rank : 83)
Query Neighborhood Hits	167	Target Neighborhood Hits	398	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

VAV3_MOUSE
θ value	θ > 10 (rank : 201)	NC score	0.053391 (rank : 84)
Query Neighborhood Hits	167	Target Neighborhood Hits	404	Shared Neighborhood Hits	16
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

VINEX_MOUSE
θ value	θ > 10 (rank : 202)	NC score	0.050409 (rank : 96)
Query Neighborhood Hits	167	Target Neighborhood Hits	286	Shared Neighborhood Hits	14
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

Hits sorted by NC score

GRLF1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	167	Target Neighborhood Hits	167	Shared Neighborhood Hits	167
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

RHG05_MOUSE
NC score	0.966223 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	167	Target Neighborhood Hits	165	Shared Neighborhood Hits	68
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

RHG05_HUMAN
NC score	0.964174 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	167	Target Neighborhood Hits	158	Shared Neighborhood Hits	65
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

RHG09_HUMAN
NC score	0.818477 (rank : 4)	θ value	8.36355e-22 (rank : 14)
Query Neighborhood Hits	167	Target Neighborhood Hits	186	Shared Neighborhood Hits	63
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

RHG12_HUMAN
NC score	0.799195 (rank : 5)	θ value	3.87602e-27 (rank : 9)
Query Neighborhood Hits	167	Target Neighborhood Hits	190	Shared Neighborhood Hits	62
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RHG12_MOUSE
NC score	0.796772 (rank : 6)	θ value	2.96777e-27 (rank : 8)
Query Neighborhood Hits	167	Target Neighborhood Hits	204	Shared Neighborhood Hits	65
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

3BP1_MOUSE
NC score	0.776584 (rank : 7)	θ value	1.52774e-15 (rank : 34)
Query Neighborhood Hits	167	Target Neighborhood Hits	238	Shared Neighborhood Hits	69
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

CHIO_MOUSE
NC score	0.775517 (rank : 8)	θ value	8.3442e-30 (rank : 4)
Query Neighborhood Hits	167	Target Neighborhood Hits	130	Shared Neighborhood Hits	61
SwissProt Accessions	Q80XD1, Q9D9W2, Q9ER57	Gene names	Chn2, Arhgap3, Bch
Domain Architecture	No domain graphic available
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

GMIP_MOUSE
NC score	0.771649 (rank : 9)	θ value	1.38178e-16 (rank : 28)
Query Neighborhood Hits	167	Target Neighborhood Hits	202	Shared Neighborhood Hits	65
SwissProt Accessions	Q6PGG2, Q6P9S3	Gene names	Gmip
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

RGAP1_HUMAN
NC score	0.768148 (rank : 10)	θ value	1.86753e-13 (rank : 45)
Query Neighborhood Hits	167	Target Neighborhood Hits	189	Shared Neighborhood Hits	62
SwissProt Accessions	Q9H0H5, Q6PJ26, Q9NWN2, Q9P250, Q9P2W2	Gene names	RACGAP1, KIAA1478, MGCRACGAP
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

3BP1_HUMAN
NC score	0.768116 (rank : 11)	θ value	1.92812e-18 (rank : 23)
Query Neighborhood Hits	167	Target Neighborhood Hits	376	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

OPHN1_HUMAN
NC score	0.764751 (rank : 12)	θ value	5.79196e-23 (rank : 11)
Query Neighborhood Hits	167	Target Neighborhood Hits	161	Shared Neighborhood Hits	64
SwissProt Accessions	O60890, Q5JQ81, Q8WX47	Gene names	OPHN1
Domain Architecture
Description	Oligophrenin 1.

GMIP_HUMAN
NC score	0.764403 (rank : 13)	θ value	3.76295e-14 (rank : 41)
Query Neighborhood Hits	167	Target Neighborhood Hits	225	Shared Neighborhood Hits	67
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

OPHN1_MOUSE
NC score	0.764068 (rank : 14)	θ value	2.59989e-23 (rank : 10)
Query Neighborhood Hits	167	Target Neighborhood Hits	174	Shared Neighborhood Hits	65
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

RGAP1_MOUSE
NC score	0.762676 (rank : 15)	θ value	2.43908e-13 (rank : 46)
Query Neighborhood Hits	167	Target Neighborhood Hits	185	Shared Neighborhood Hits	62
SwissProt Accessions	Q9WVM1, Q3THR5, Q3TI41, Q3TM81	Gene names	Racgap1, Mgcracgap
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RHG01_HUMAN
NC score	0.749312 (rank : 16)	θ value	4.74913e-17 (rank : 27)
Query Neighborhood Hits	167	Target Neighborhood Hits	75	Shared Neighborhood Hits	62
SwissProt Accessions	Q07960	Gene names	ARHGAP1, CDC42GAP, RHOGAP1
Domain Architecture
Description	Rho-GTPase-activating protein 1 (GTPase-activating protein rhoOGAP) (Rho-related small GTPase protein activator) (CDC42 GTPase-activating protein) (p50-RhoGAP).

RHG06_HUMAN
NC score	0.746671 (rank : 17)	θ value	1.33837e-11 (rank : 49)
Query Neighborhood Hits	167	Target Neighborhood Hits	114	Shared Neighborhood Hits	63
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

CHIN_MOUSE
NC score	0.745201 (rank : 18)	θ value	9.2256e-29 (rank : 7)
Query Neighborhood Hits	167	Target Neighborhood Hits	229	Shared Neighborhood Hits	62
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIN_HUMAN
NC score	0.743111 (rank : 19)	θ value	7.06379e-29 (rank : 5)
Query Neighborhood Hits	167	Target Neighborhood Hits	227	Shared Neighborhood Hits	61
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

RHG06_MOUSE
NC score	0.743083 (rank : 20)	θ value	3.89403e-11 (rank : 51)
Query Neighborhood Hits	167	Target Neighborhood Hits	105	Shared Neighborhood Hits	62
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

CHIO_HUMAN
NC score	0.741961 (rank : 21)	θ value	7.06379e-29 (rank : 6)
Query Neighborhood Hits	167	Target Neighborhood Hits	220	Shared Neighborhood Hits	61
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

TCGAP_MOUSE
NC score	0.731303 (rank : 22)	θ value	1.80466e-16 (rank : 31)
Query Neighborhood Hits	167	Target Neighborhood Hits	409	Shared Neighborhood Hits	74
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

RHG18_HUMAN
NC score	0.729330 (rank : 23)	θ value	1.133e-10 (rank : 53)
Query Neighborhood Hits	167	Target Neighborhood Hits	90	Shared Neighborhood Hits	62
SwissProt Accessions	Q8N392, Q58EZ3, Q6P679, Q6PJD7, Q96S64	Gene names	ARHGAP18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18 (MacGAP).

RHG18_MOUSE
NC score	0.728100 (rank : 24)	θ value	3.89403e-11 (rank : 52)
Query Neighborhood Hits	167	Target Neighborhood Hits	110	Shared Neighborhood Hits	62
SwissProt Accessions	Q8K0Q5, Q8BP03, Q8R196	Gene names	Arhgap18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18.

RHG08_MOUSE
NC score	0.723594 (rank : 25)	θ value	1.33837e-11 (rank : 50)
Query Neighborhood Hits	167	Target Neighborhood Hits	73	Shared Neighborhood Hits	62
SwissProt Accessions	Q9CXP4, Q99JY7	Gene names	Arhgap8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RHG08_HUMAN
NC score	0.721615 (rank : 26)	θ value	3.52202e-12 (rank : 48)
Query Neighborhood Hits	167	Target Neighborhood Hits	88	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NSG0, O75983, O95695, Q96RW1, Q96RW2, Q9HA49, Q9HC46, Q9NVX8, Q9NXL1, Q9UH20	Gene names	ARHGAP8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

ABR_HUMAN
NC score	0.719266 (rank : 27)	θ value	1.29031e-22 (rank : 12)
Query Neighborhood Hits	167	Target Neighborhood Hits	166	Shared Neighborhood Hits	63
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

RHG26_HUMAN
NC score	0.715389 (rank : 28)	θ value	2.87452e-22 (rank : 13)
Query Neighborhood Hits	167	Target Neighborhood Hits	281	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

RHG04_HUMAN
NC score	0.710019 (rank : 29)	θ value	2.13179e-17 (rank : 25)
Query Neighborhood Hits	167	Target Neighborhood Hits	307	Shared Neighborhood Hits	66
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

BCR_HUMAN
NC score	0.705454 (rank : 30)	θ value	1.42661e-21 (rank : 16)
Query Neighborhood Hits	167	Target Neighborhood Hits	204	Shared Neighborhood Hits	62
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

SRGP2_HUMAN
NC score	0.701108 (rank : 31)	θ value	9.24701e-21 (rank : 19)
Query Neighborhood Hits	167	Target Neighborhood Hits	331	Shared Neighborhood Hits	65
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

RBP1_MOUSE
NC score	0.701089 (rank : 32)	θ value	4.74913e-17 (rank : 26)
Query Neighborhood Hits	167	Target Neighborhood Hits	493	Shared Neighborhood Hits	68
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

TAGAP_HUMAN
NC score	0.700019 (rank : 33)	θ value	1.52774e-15 (rank : 36)
Query Neighborhood Hits	167	Target Neighborhood Hits	82	Shared Neighborhood Hits	60
SwissProt Accessions	Q8N103, Q2NKM8, Q8NI40, Q96KZ2, Q96QA2	Gene names	TAGAP, TAGAP1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

SRGP2_MOUSE
NC score	0.693616 (rank : 34)	θ value	1.74391e-19 (rank : 21)
Query Neighborhood Hits	167	Target Neighborhood Hits	324	Shared Neighborhood Hits	65
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

RHG25_MOUSE
NC score	0.693584 (rank : 35)	θ value	4.44505e-15 (rank : 37)
Query Neighborhood Hits	167	Target Neighborhood Hits	492	Shared Neighborhood Hits	66
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RBP1_HUMAN
NC score	0.688701 (rank : 36)	θ value	2.13179e-17 (rank : 24)
Query Neighborhood Hits	167	Target Neighborhood Hits	521	Shared Neighborhood Hits	68
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

TAGAP_MOUSE
NC score	0.688329 (rank : 37)	θ value	3.29651e-10 (rank : 54)
Query Neighborhood Hits	167	Target Neighborhood Hits	83	Shared Neighborhood Hits	60
SwissProt Accessions	Q8K2L9, Q920D6	Gene names	Tagap, Tagap1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

SRGP1_HUMAN
NC score	0.687666 (rank : 38)	θ value	1.86321e-21 (rank : 17)
Query Neighborhood Hits	167	Target Neighborhood Hits	390	Shared Neighborhood Hits	66
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

RHG07_MOUSE
NC score	0.681892 (rank : 39)	θ value	1.80466e-16 (rank : 29)
Query Neighborhood Hits	167	Target Neighborhood Hits	103	Shared Neighborhood Hits	63
SwissProt Accessions	Q9R0Z9, Q8R541	Gene names	Dlc1, Arhgap7, Stard12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein homolog) (Dlc-1) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

FNBP2_HUMAN
NC score	0.681509 (rank : 40)	θ value	5.07402e-19 (rank : 22)
Query Neighborhood Hits	167	Target Neighborhood Hits	432	Shared Neighborhood Hits	68
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

RHG07_HUMAN
NC score	0.675413 (rank : 41)	θ value	1.52774e-15 (rank : 35)
Query Neighborhood Hits	167	Target Neighborhood Hits	108	Shared Neighborhood Hits	62
SwissProt Accessions	Q96QB1, O14868, O43199, Q9C0E0	Gene names	DLC1, ARHGAP7, KIAA1723, STARD12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein) (Dlc-1) (HP protein) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

RHG25_HUMAN
NC score	0.669745 (rank : 42)	θ value	6.41864e-14 (rank : 42)
Query Neighborhood Hits	167	Target Neighborhood Hits	550	Shared Neighborhood Hits	67
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

TCGAP_HUMAN
NC score	0.648517 (rank : 43)	θ value	1.80466e-16 (rank : 30)
Query Neighborhood Hits	167	Target Neighborhood Hits	872	Shared Neighborhood Hits	74
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

STA13_HUMAN
NC score	0.641241 (rank : 44)	θ value	1.16975e-15 (rank : 33)
Query Neighborhood Hits	167	Target Neighborhood Hits	89	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y3M8, Q5HYH1, Q5TAE3, Q6UN61, Q86TP6, Q86WQ3, Q86XT1	Gene names	STARD13, DLC2, GT650
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13) (46H23.2) (Deleted in liver cancer protein 2) (Rho GTPase-activating protein).

STAR8_MOUSE
NC score	0.637477 (rank : 45)	θ value	2.88119e-14 (rank : 40)
Query Neighborhood Hits	167	Target Neighborhood Hits	101	Shared Neighborhood Hits	59
SwissProt Accessions	Q8K031, Q3UZC7, Q6A0A8, Q6P5E0, Q8R3X8	Gene names	Stard8, Kiaa0189
Domain Architecture	No domain graphic available
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

CEND2_HUMAN
NC score	0.631924 (rank : 46)	θ value	1.2077e-20 (rank : 20)
Query Neighborhood Hits	167	Target Neighborhood Hits	166	Shared Neighborhood Hits	60
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

STAR8_HUMAN
NC score	0.630933 (rank : 47)	θ value	2.43908e-13 (rank : 47)
Query Neighborhood Hits	167	Target Neighborhood Hits	216	Shared Neighborhood Hits	60
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

STA13_MOUSE
NC score	0.630036 (rank : 48)	θ value	1.68911e-14 (rank : 39)
Query Neighborhood Hits	167	Target Neighborhood Hits	89	Shared Neighborhood Hits	58
SwissProt Accessions	Q923Q2, Q8K369	Gene names	Stard13
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13).

CE005_HUMAN
NC score	0.628495 (rank : 49)	θ value	1.86753e-13 (rank : 44)
Query Neighborhood Hits	167	Target Neighborhood Hits	213	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

CE005_MOUSE
NC score	0.627825 (rank : 50)	θ value	8.38298e-14 (rank : 43)
Query Neighborhood Hits	167	Target Neighborhood Hits	238	Shared Neighborhood Hits	63
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

CEND3_MOUSE
NC score	0.595937 (rank : 51)	θ value	4.02038e-16 (rank : 32)
Query Neighborhood Hits	167	Target Neighborhood Hits	228	Shared Neighborhood Hits	68
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

CEND3_HUMAN
NC score	0.583936 (rank : 52)	θ value	1.29331e-14 (rank : 38)
Query Neighborhood Hits	167	Target Neighborhood Hits	275	Shared Neighborhood Hits	68
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

CEND1_MOUSE
NC score	0.531384 (rank : 53)	θ value	4.30538e-10 (rank : 55)
Query Neighborhood Hits	167	Target Neighborhood Hits	260	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

CEND1_HUMAN
NC score	0.511332 (rank : 54)	θ value	2.79066e-09 (rank : 57)
Query Neighborhood Hits	167	Target Neighborhood Hits	284	Shared Neighborhood Hits	66
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

K1688_MOUSE
NC score	0.492234 (rank : 55)	θ value	0.000158464 (rank : 59)
Query Neighborhood Hits	167	Target Neighborhood Hits	188	Shared Neighborhood Hits	61
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

K1688_HUMAN
NC score	0.475331 (rank : 56)	θ value	0.00020696 (rank : 60)
Query Neighborhood Hits	167	Target Neighborhood Hits	217	Shared Neighborhood Hits	60
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

MYO9B_MOUSE
NC score	0.412280 (rank : 57)	θ value	1.09232e-21 (rank : 15)
Query Neighborhood Hits	167	Target Neighborhood Hits	311	Shared Neighborhood Hits	67
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

MYO9B_HUMAN
NC score	0.406546 (rank : 58)	θ value	2.43343e-21 (rank : 18)
Query Neighborhood Hits	167	Target Neighborhood Hits	641	Shared Neighborhood Hits	72
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

P85A_HUMAN
NC score	0.388942 (rank : 59)	θ value	2.13673e-09 (rank : 56)
Query Neighborhood Hits	167	Target Neighborhood Hits	479	Shared Neighborhood Hits	63
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

P85A_MOUSE
NC score	0.385559 (rank : 60)	θ value	8.11959e-09 (rank : 58)
Query Neighborhood Hits	167	Target Neighborhood Hits	435	Shared Neighborhood Hits	63
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

I5P2_HUMAN
NC score	0.329099 (rank : 61)	θ value	0.00035302 (rank : 61)
Query Neighborhood Hits	167	Target Neighborhood Hits	86	Shared Neighborhood Hits	52
SwissProt Accessions	P32019, Q5VSG9, Q5VSH0, Q5VSH1, Q658Q5, Q6P6D4, Q6PD53, Q86YE1	Gene names	INPP5B
Domain Architecture	No domain graphic available
Description	Type II inositol-1,4,5-trisphosphate 5-phosphatase precursor (EC 3.1.3.36) (Phosphoinositide 5-phosphatase) (5PTase) (75 kDa inositol polyphosphate-5-phosphatase).

OCRL_HUMAN
NC score	0.313967 (rank : 62)	θ value	0.0148317 (rank : 62)
Query Neighborhood Hits	167	Target Neighborhood Hits	77	Shared Neighborhood Hits	51
SwissProt Accessions	Q01968, O60800, Q15684, Q15774, Q5JQF1, Q5JQF2, Q9UJG5, Q9UMA5	Gene names	OCRL, INPP5F, OCRL1
Domain Architecture
Description	Inositol polyphosphate 5-phosphatase OCRL-1 (EC 3.1.3.36) (Lowe oculocerebrorenal syndrome protein).

P85B_HUMAN
NC score	0.100997 (rank : 63)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	167	Target Neighborhood Hits	543	Shared Neighborhood Hits	30
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

CENB2_HUMAN
NC score	0.077767 (rank : 64)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	167	Target Neighborhood Hits	425	Shared Neighborhood Hits	15
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

GRP3_HUMAN
NC score	0.077246 (rank : 65)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	167	Target Neighborhood Hits	131	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IV61, O94931	Gene names	RASGRP3, GRP3, KIAA0846
Domain Architecture
Description	RAS guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1).

TCRG1_MOUSE
NC score	0.076617 (rank : 66)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	167	Target Neighborhood Hits	947	Shared Neighborhood Hits	28
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

TCRG1_HUMAN
NC score	0.076337 (rank : 67)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	167	Target Neighborhood Hits	929	Shared Neighborhood Hits	27
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

CENB5_HUMAN
NC score	0.073808 (rank : 68)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	167	Target Neighborhood Hits	395	Shared Neighborhood Hits	13
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

P85B_MOUSE
NC score	0.072635 (rank : 69)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	167	Target Neighborhood Hits	519	Shared Neighborhood Hits	26
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

CENB1_HUMAN
NC score	0.071985 (rank : 70)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	167	Target Neighborhood Hits	383	Shared Neighborhood Hits	13
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

PCTL_MOUSE
NC score	0.068436 (rank : 71)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	167	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JMD3	Gene names	Stard10, Pctpl, Sdccag28, Sdccagg28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28 homolog).

PCTL_HUMAN
NC score	0.067654 (rank : 72)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	167	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y365, O60532	Gene names	STARD10, SDCCAG28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28) (Antigen NY-CO-28).

FA13A_HUMAN
NC score	0.065870 (rank : 73)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	167	Target Neighborhood Hits	102	Shared Neighborhood Hits	6
SwissProt Accessions	O94988, Q8NBA3	Gene names	FAM13A1, KIAA0914
Domain Architecture	No domain graphic available
Description	Protein FAM13A1.

FA13A_MOUSE
NC score	0.065370 (rank : 74)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	167	Target Neighborhood Hits	83	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BGI4, Q8BZ91	Gene names	Fam13a1, Precm1
Domain Architecture	No domain graphic available
Description	Protein FAM13A1 (Precm1 protein).

NCK2_HUMAN
NC score	0.059812 (rank : 75)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	167	Target Neighborhood Hits	310	Shared Neighborhood Hits	15
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

P55G_HUMAN
NC score	0.056331 (rank : 76)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	167	Target Neighborhood Hits	451	Shared Neighborhood Hits	12
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

CIP4_HUMAN
NC score	0.056096 (rank : 77)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	167	Target Neighborhood Hits	374	Shared Neighborhood Hits	14
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

DDEF2_HUMAN
NC score	0.055825 (rank : 78)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	167	Target Neighborhood Hits	599	Shared Neighborhood Hits	26
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

PDZD8_HUMAN
NC score	0.055600 (rank : 79)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	167	Target Neighborhood Hits	185	Shared Neighborhood Hits	12
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

P55G_MOUSE
NC score	0.055100 (rank : 80)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	167	Target Neighborhood Hits	401	Shared Neighborhood Hits	10
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

DDEF2_MOUSE
NC score	0.054177 (rank : 81)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	167	Target Neighborhood Hits	625	Shared Neighborhood Hits	26
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

GRAP_HUMAN
NC score	0.054047 (rank : 82)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	167	Target Neighborhood Hits	307	Shared Neighborhood Hits	13
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

VAV3_HUMAN
NC score	0.053720 (rank : 83)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	167	Target Neighborhood Hits	398	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

VAV3_MOUSE
NC score	0.053391 (rank : 84)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	167	Target Neighborhood Hits	404	Shared Neighborhood Hits	16
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

CENG1_HUMAN
NC score	0.052730 (rank : 85)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	167	Target Neighborhood Hits	544	Shared Neighborhood Hits	44
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

GRB2_HUMAN
NC score	0.052547 (rank : 86)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	167	Target Neighborhood Hits	310	Shared Neighborhood Hits	13
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
NC score	0.052539 (rank : 87)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	167	Target Neighborhood Hits	312	Shared Neighborhood Hits	13
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

CENG1_MOUSE
NC score	0.052194 (rank : 88)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	167	Target Neighborhood Hits	531	Shared Neighborhood Hits	35
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

PRP40_HUMAN
NC score	0.052001 (rank : 89)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	167	Target Neighborhood Hits	442	Shared Neighborhood Hits	14
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

CENA2_HUMAN
NC score	0.051554 (rank : 90)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	167	Target Neighborhood Hits	83	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

SMP1L_HUMAN
NC score	0.051479 (rank : 91)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	167	Target Neighborhood Hits	74	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

FA13C_HUMAN
NC score	0.051460 (rank : 92)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	167	Target Neighborhood Hits	94	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NE31, Q99787	Gene names	FAM13C1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

GRAP_MOUSE
NC score	0.051279 (rank : 93)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	167	Target Neighborhood Hits	309	Shared Neighborhood Hits	13
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

SMP1L_MOUSE
NC score	0.051195 (rank : 94)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	167	Target Neighborhood Hits	70	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

DDFL1_HUMAN
NC score	0.051034 (rank : 95)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	167	Target Neighborhood Hits	353	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

VINEX_MOUSE
NC score	0.050409 (rank : 96)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	167	Target Neighborhood Hits	286	Shared Neighborhood Hits	14
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

DAPP1_MOUSE
NC score	0.050217 (rank : 97)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	167	Target Neighborhood Hits	225	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

RAB10_HUMAN
NC score	0.049377 (rank : 98)	θ value	0.125558 (rank : 66)
Query Neighborhood Hits	167	Target Neighborhood Hits	278	Shared Neighborhood Hits	42
SwissProt Accessions	P61026, O88386, Q6IA52, Q9D7X6, Q9H0T3	Gene names	RAB10
Domain Architecture
Description	Ras-related protein Rab-10.

RAB10_MOUSE
NC score	0.049377 (rank : 99)	θ value	0.125558 (rank : 67)
Query Neighborhood Hits	167	Target Neighborhood Hits	278	Shared Neighborhood Hits	42
SwissProt Accessions	P61027, O88386, Q9D7X6	Gene names	Rab10
Domain Architecture
Description	Ras-related protein Rab-10.

RAB8A_MOUSE
NC score	0.048842 (rank : 100)	θ value	0.365318 (rank : 81)
Query Neighborhood Hits	167	Target Neighborhood Hits	269	Shared Neighborhood Hits	43
SwissProt Accessions	P55258, Q8VCF6	Gene names	Rab8a, Mel, Rab8
Domain Architecture
Description	Ras-related protein Rab-8A (Oncogene c-mel).

RAB8A_HUMAN
NC score	0.048786 (rank : 101)	θ value	0.365318 (rank : 80)
Query Neighborhood Hits	167	Target Neighborhood Hits	269	Shared Neighborhood Hits	43
SwissProt Accessions	P61006, P24407	Gene names	RAB8A, MEL, RAB8
Domain Architecture
Description	Ras-related protein Rab-8A (Oncogene c-mel).

RAB26_HUMAN
NC score	0.048273 (rank : 102)	θ value	0.279714 (rank : 76)
Query Neighborhood Hits	167	Target Neighborhood Hits	280	Shared Neighborhood Hits	41
SwissProt Accessions	Q9ULW5, Q6NXS7	Gene names	RAB26
Domain Architecture
Description	Ras-related protein Rab-26.

DIRA1_MOUSE
NC score	0.048175 (rank : 103)	θ value	5.27518 (rank : 127)
Query Neighborhood Hits	167	Target Neighborhood Hits	233	Shared Neighborhood Hits	42
SwissProt Accessions	Q91Z61	Gene names	Diras1, Gbts1
Domain Architecture	No domain graphic available
Description	GTP-binding protein Di-Ras1 (Distinct subgroup of the Ras family member 1) (Small GTP-binding tumor suppressor 1).

RAB13_HUMAN
NC score	0.048065 (rank : 104)	θ value	0.279714 (rank : 74)
Query Neighborhood Hits	167	Target Neighborhood Hits	286	Shared Neighborhood Hits	42
SwissProt Accessions	P51153, Q96GU4	Gene names	RAB13
Domain Architecture
Description	Ras-related protein Rab-13.

RAB13_MOUSE
NC score	0.048019 (rank : 105)	θ value	0.279714 (rank : 75)
Query Neighborhood Hits	167	Target Neighborhood Hits	289	Shared Neighborhood Hits	42
SwissProt Accessions	Q9DD03	Gene names	Rab13
Domain Architecture
Description	Ras-related protein Rab-13.

RAB3C_HUMAN
NC score	0.047908 (rank : 106)	θ value	0.0736092 (rank : 63)
Query Neighborhood Hits	167	Target Neighborhood Hits	272	Shared Neighborhood Hits	41
SwissProt Accessions	Q96E17	Gene names	RAB3C
Domain Architecture
Description	Ras-related protein Rab-3C.

RAB4B_MOUSE
NC score	0.047862 (rank : 107)	θ value	5.27518 (rank : 131)
Query Neighborhood Hits	167	Target Neighborhood Hits	283	Shared Neighborhood Hits	43
SwissProt Accessions	Q91ZR1	Gene names	Rab4b, Rab4
Domain Architecture
Description	Ras-related protein Rab-4B.

RAB4B_HUMAN
NC score	0.047861 (rank : 108)	θ value	5.27518 (rank : 130)
Query Neighborhood Hits	167	Target Neighborhood Hits	283	Shared Neighborhood Hits	43
SwissProt Accessions	P61018, P22750, Q7Z514, Q9HBR6	Gene names	RAB4B
Domain Architecture
Description	Ras-related protein Rab-4B.

RAB26_MOUSE
NC score	0.047694 (rank : 109)	θ value	0.279714 (rank : 77)
Query Neighborhood Hits	167	Target Neighborhood Hits	287	Shared Neighborhood Hits	41
SwissProt Accessions	Q504M8	Gene names	Rab26
Domain Architecture	No domain graphic available
Description	Ras-related protein Rab-26.

RAB38_HUMAN
NC score	0.047656 (rank : 110)	θ value	1.81305 (rank : 101)
Query Neighborhood Hits	167	Target Neighborhood Hits	255	Shared Neighborhood Hits	42
SwissProt Accessions	P57729, Q53XK7	Gene names	RAB38
Domain Architecture
Description	Ras-related protein Rab-38 (Antigen NY-MEL-1).

DIRA2_MOUSE
NC score	0.047288 (rank : 111)	θ value	0.125558 (rank : 65)
Query Neighborhood Hits	167	Target Neighborhood Hits	237	Shared Neighborhood Hits	42
SwissProt Accessions	Q5PR73	Gene names	Diras2
Domain Architecture	No domain graphic available
Description	GTP-binding protein Di-Ras2 (Distinct subgroup of the Ras family member 2).

RAB3C_MOUSE
NC score	0.047250 (rank : 112)	θ value	0.21417 (rank : 71)
Query Neighborhood Hits	167	Target Neighborhood Hits	270	Shared Neighborhood Hits	41
SwissProt Accessions	P62823, Q62858, Q62974, Q63482, Q9CXQ1	Gene names	Rab3c
Domain Architecture	No domain graphic available
Description	Ras-related protein Rab-3C.

RAB15_MOUSE
NC score	0.047164 (rank : 113)	θ value	0.365318 (rank : 79)
Query Neighborhood Hits	167	Target Neighborhood Hits	284	Shared Neighborhood Hits	41
SwissProt Accessions	Q8K386	Gene names	Rab15
Domain Architecture
Description	Ras-related protein Rab-15.

RAB37_MOUSE
NC score	0.047132 (rank : 114)	θ value	0.47712 (rank : 83)
Query Neighborhood Hits	167	Target Neighborhood Hits	271	Shared Neighborhood Hits	41
SwissProt Accessions	Q9JKM7, Q8C7E1	Gene names	Rab37
Domain Architecture
Description	Ras-related protein Rab-37.

RAB8B_HUMAN
NC score	0.046922 (rank : 115)	θ value	1.38821 (rank : 97)
Query Neighborhood Hits	167	Target Neighborhood Hits	275	Shared Neighborhood Hits	42
SwissProt Accessions	Q92930, Q9P293	Gene names	RAB8B
Domain Architecture
Description	Ras-related protein Rab-8B.

RAB15_HUMAN
NC score	0.046825 (rank : 116)	θ value	0.47712 (rank : 82)
Query Neighborhood Hits	167	Target Neighborhood Hits	283	Shared Neighborhood Hits	41
SwissProt Accessions	P59190, Q86TX7, Q8IW89	Gene names	RAB15
Domain Architecture
Description	Ras-related protein Rab-15.

RAB8B_MOUSE
NC score	0.046820 (rank : 117)	θ value	1.38821 (rank : 98)
Query Neighborhood Hits	167	Target Neighborhood Hits	277	Shared Neighborhood Hits	42
SwissProt Accessions	P61028, Q3U1Z3	Gene names	Rab8b
Domain Architecture
Description	Ras-related protein Rab-8B.

RAB37_HUMAN
NC score	0.046577 (rank : 118)	θ value	0.813845 (rank : 92)
Query Neighborhood Hits	167	Target Neighborhood Hits	271	Shared Neighborhood Hits	41
SwissProt Accessions	Q96AX2	Gene names	RAB37
Domain Architecture
Description	Ras-related protein Rab-37.

RAB38_MOUSE
NC score	0.046161 (rank : 119)	θ value	2.36792 (rank : 110)
Query Neighborhood Hits	167	Target Neighborhood Hits	256	Shared Neighborhood Hits	41
SwissProt Accessions	Q8QZZ8, Q9D7E8	Gene names	Rab38
Domain Architecture
Description	Ras-related protein Rab-38.

RB27B_MOUSE
NC score	0.045708 (rank : 120)	θ value	1.81305 (rank : 104)
Query Neighborhood Hits	167	Target Neighborhood Hits	276	Shared Neighborhood Hits	41
SwissProt Accessions	Q99P58, Q8CIX0	Gene names	Rab27b
Domain Architecture
Description	Ras-related protein Rab-27B.

RB27B_HUMAN
NC score	0.045685 (rank : 121)	θ value	1.81305 (rank : 103)
Query Neighborhood Hits	167	Target Neighborhood Hits	281	Shared Neighborhood Hits	41
SwissProt Accessions	O00194, Q9BZB6	Gene names	RAB27B
Domain Architecture
Description	Ras-related protein Rab-27B (C25KG).

RAB35_HUMAN
NC score	0.045497 (rank : 122)	θ value	0.62314 (rank : 87)
Query Neighborhood Hits	167	Target Neighborhood Hits	287	Shared Neighborhood Hits	41
SwissProt Accessions	Q15286	Gene names	RAB35, RAB1C, RAY
Domain Architecture
Description	Ras-related protein Rab-35 (Rab-1C) (GTP-binding protein RAY).

RAB35_MOUSE
NC score	0.045497 (rank : 123)	θ value	0.62314 (rank : 88)
Query Neighborhood Hits	167	Target Neighborhood Hits	287	Shared Neighborhood Hits	41
SwissProt Accessions	Q6PHN9	Gene names	Rab35
Domain Architecture	No domain graphic available
Description	Ras-related protein Rab-35.

DIRA2_HUMAN
NC score	0.044955 (rank : 124)	θ value	0.125558 (rank : 64)
Query Neighborhood Hits	167	Target Neighborhood Hits	235	Shared Neighborhood Hits	41
SwissProt Accessions	Q96HU8	Gene names	DIRAS2
Domain Architecture	No domain graphic available
Description	GTP-binding protein Di-Ras2 (Distinct subgroup of the Ras family member 2).

RB39B_MOUSE
NC score	0.044594 (rank : 125)	θ value	2.36792 (rank : 112)
Query Neighborhood Hits	167	Target Neighborhood Hits	277	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BHC1, Q3TUJ3	Gene names	Rab39b
Domain Architecture
Description	Ras-related protein Rab-39B.

RB39B_HUMAN
NC score	0.044573 (rank : 126)	θ value	2.36792 (rank : 111)
Query Neighborhood Hits	167	Target Neighborhood Hits	279	Shared Neighborhood Hits	43
SwissProt Accessions	Q96DA2, Q5JT79, Q8NEX3	Gene names	RAB39B
Domain Architecture
Description	Ras-related protein Rab-39B.

RAB7_HUMAN
NC score	0.043815 (rank : 127)	θ value	0.47712 (rank : 84)
Query Neighborhood Hits	167	Target Neighborhood Hits	274	Shared Neighborhood Hits	41
SwissProt Accessions	P51149, Q9UPB0	Gene names	RAB7
Domain Architecture
Description	Ras-related protein Rab-7.

RAB7_MOUSE
NC score	0.043815 (rank : 128)	θ value	0.47712 (rank : 85)
Query Neighborhood Hits	167	Target Neighborhood Hits	274	Shared Neighborhood Hits	41
SwissProt Accessions	P51150	Gene names	Rab7
Domain Architecture
Description	Ras-related protein Rab-7.

RASN_HUMAN
NC score	0.043470 (rank : 129)	θ value	0.47712 (rank : 86)
Query Neighborhood Hits	167	Target Neighborhood Hits	259	Shared Neighborhood Hits	42
SwissProt Accessions	P01111, Q14971, Q15104, Q15282	Gene names	NRAS
Domain Architecture
Description	GTPase NRas precursor (Transforming protein N-Ras).

RASN_MOUSE
NC score	0.043193 (rank : 130)	θ value	0.62314 (rank : 89)
Query Neighborhood Hits	167	Target Neighborhood Hits	258	Shared Neighborhood Hits	42
SwissProt Accessions	P08556	Gene names	Nras
Domain Architecture
Description	GTPase NRas precursor (Transforming protein N-Ras).

RAB17_MOUSE
NC score	0.042148 (rank : 131)	θ value	0.813845 (rank : 91)
Query Neighborhood Hits	167	Target Neighborhood Hits	277	Shared Neighborhood Hits	40
SwissProt Accessions	P35292, Q921D2, Q9D723	Gene names	Rab17
Domain Architecture
Description	Ras-related protein Rab-17.

RASE_MOUSE
NC score	0.041676 (rank : 132)	θ value	1.81305 (rank : 102)
Query Neighborhood Hits	167	Target Neighborhood Hits	209	Shared Neighborhood Hits	40
SwissProt Accessions	Q7TN89	Gene names	Eras
Domain Architecture	No domain graphic available
Description	GTPase ERas precursor (E-Ras) (Embryonic stem cell-expressed Ras).

RASE_HUMAN
NC score	0.041046 (rank : 133)	θ value	5.27518 (rank : 132)
Query Neighborhood Hits	167	Target Neighborhood Hits	214	Shared Neighborhood Hits	41
SwissProt Accessions	Q7Z444	Gene names	ERAS, HRAS2, HRASP
Domain Architecture	No domain graphic available
Description	GTPase ERas precursor (E-Ras) (Embryonic stem cell-expressed Ras).

RASH_MOUSE
NC score	0.040236 (rank : 134)	θ value	6.88961 (rank : 151)
Query Neighborhood Hits	167	Target Neighborhood Hits	257	Shared Neighborhood Hits	41
SwissProt Accessions	Q61411, Q80WD2	Gene names	Hras1, Hras
Domain Architecture
Description	GTPase HRas precursor (Transforming protein p21) (p21ras) (H-Ras-1) (c-H-ras).

RASH_HUMAN
NC score	0.040168 (rank : 135)	θ value	6.88961 (rank : 150)
Query Neighborhood Hits	167	Target Neighborhood Hits	263	Shared Neighborhood Hits	41
SwissProt Accessions	P01112, Q14080, Q6FHV9	Gene names	HRAS, HRAS1
Domain Architecture
Description	GTPase HRas precursor (Transforming protein p21) (p21ras) (H-Ras-1) (c-H-ras).

RALB_HUMAN
NC score	0.039001 (rank : 136)	θ value	3.0926 (rank : 121)
Query Neighborhood Hits	167	Target Neighborhood Hits	274	Shared Neighborhood Hits	41
SwissProt Accessions	P11234	Gene names	RALB
Domain Architecture
Description	Ras-related protein Ral-B.

RALB_MOUSE
NC score	0.038237 (rank : 137)	θ value	6.88961 (rank : 149)
Query Neighborhood Hits	167	Target Neighborhood Hits	274	Shared Neighborhood Hits	41
SwissProt Accessions	Q9JIW9, Q3TVS5	Gene names	Ralb
Domain Architecture
Description	Ras-related protein Ral-B.

SPR1B_HUMAN
NC score	0.036444 (rank : 138)	θ value	0.813845 (rank : 93)
Query Neighborhood Hits	167	Target Neighborhood Hits	102	Shared Neighborhood Hits	6
SwissProt Accessions	P22528, P22529, P22530, Q5T524	Gene names	SPRR1B
Domain Architecture	No domain graphic available
Description	Cornifin B (Small proline-rich protein IB) (SPR-IB) (14.9 kDa pancornulin).

SPR1A_MOUSE
NC score	0.034612 (rank : 139)	θ value	0.125558 (rank : 68)
Query Neighborhood Hits	167	Target Neighborhood Hits	343	Shared Neighborhood Hits	14
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

SPR1A_HUMAN
NC score	0.033313 (rank : 140)	θ value	1.06291 (rank : 95)
Query Neighborhood Hits	167	Target Neighborhood Hits	136	Shared Neighborhood Hits	7
SwissProt Accessions	P35321, Q9UDG4	Gene names	SPRR1A
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein IA) (SPR-IA) (SPRK) (19 kDa pancornulin).

S23IP_MOUSE
NC score	0.031353 (rank : 141)	θ value	0.21417 (rank : 72)
Query Neighborhood Hits	167	Target Neighborhood Hits	363	Shared Neighborhood Hits	16
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

SPR1B_MOUSE
NC score	0.030339 (rank : 142)	θ value	1.06291 (rank : 96)
Query Neighborhood Hits	167	Target Neighborhood Hits	395	Shared Neighborhood Hits	16
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

DOK1_MOUSE
NC score	0.024164 (rank : 143)	θ value	0.163984 (rank : 69)
Query Neighborhood Hits	167	Target Neighborhood Hits	82	Shared Neighborhood Hits	3
SwissProt Accessions	P97465, Q9R213	Gene names	Dok1, Dok
Domain Architecture
Description	Docking protein 1 (Downstream of tyrosine kinase 1) (p62(dok)).

HSF1_MOUSE
NC score	0.021544 (rank : 144)	θ value	4.03905 (rank : 123)
Query Neighborhood Hits	167	Target Neighborhood Hits	267	Shared Neighborhood Hits	13
SwissProt Accessions	P38532, O70462	Gene names	Hsf1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

SAPS1_HUMAN
NC score	0.020021 (rank : 145)	θ value	1.06291 (rank : 94)
Query Neighborhood Hits	167	Target Neighborhood Hits	704	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

SPT5H_MOUSE
NC score	0.019873 (rank : 146)	θ value	2.36792 (rank : 114)
Query Neighborhood Hits	167	Target Neighborhood Hits	437	Shared Neighborhood Hits	15
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

SPT5H_HUMAN
NC score	0.019853 (rank : 147)	θ value	2.36792 (rank : 113)
Query Neighborhood Hits	167	Target Neighborhood Hits	436	Shared Neighborhood Hits	15
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

T2EA_MOUSE
NC score	0.019495 (rank : 148)	θ value	1.81305 (rank : 108)
Query Neighborhood Hits	167	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D0D5, Q544T0	Gene names	Gtf2e1
Domain Architecture
Description	Transcription initiation factor IIE subunit alpha (TFIIE-alpha) (General transcription factor IIE 56 kDa subunit).

K1802_HUMAN
NC score	0.018678 (rank : 149)	θ value	0.813845 (rank : 90)
Query Neighborhood Hits	167	Target Neighborhood Hits	1378	Shared Neighborhood Hits	32
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

DSPP_HUMAN
NC score	0.018111 (rank : 150)	θ value	0.163984 (rank : 70)
Query Neighborhood Hits	167	Target Neighborhood Hits	645	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

MKL1_MOUSE
NC score	0.017964 (rank : 151)	θ value	3.0926 (rank : 120)
Query Neighborhood Hits	167	Target Neighborhood Hits	667	Shared Neighborhood Hits	16
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

K1543_HUMAN
NC score	0.017915 (rank : 152)	θ value	3.0926 (rank : 119)
Query Neighborhood Hits	167	Target Neighborhood Hits	435	Shared Neighborhood Hits	13
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

GTSE1_MOUSE
NC score	0.017837 (rank : 153)	θ value	3.0926 (rank : 118)
Query Neighborhood Hits	167	Target Neighborhood Hits	245	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R080, O89015, Q9CSG9	Gene names	Gtse1, B99
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (Gtse-1) (B99 protein).

RGS3_MOUSE
NC score	0.017255 (rank : 154)	θ value	8.99809 (rank : 165)
Query Neighborhood Hits	167	Target Neighborhood Hits	1621	Shared Neighborhood Hits	34
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

ATX7_MOUSE
NC score	0.016529 (rank : 155)	θ value	3.0926 (rank : 116)
Query Neighborhood Hits	167	Target Neighborhood Hits	328	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

SON_HUMAN
NC score	0.016458 (rank : 156)	θ value	1.81305 (rank : 106)
Query Neighborhood Hits	167	Target Neighborhood Hits	1568	Shared Neighborhood Hits	32
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

CI093_HUMAN
NC score	0.014485 (rank : 157)	θ value	6.88961 (rank : 139)
Query Neighborhood Hits	167	Target Neighborhood Hits	1088	Shared Neighborhood Hits	23
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

SYNC_HUMAN
NC score	0.014133 (rank : 158)	θ value	1.81305 (rank : 107)
Query Neighborhood Hits	167	Target Neighborhood Hits	47	Shared Neighborhood Hits	2
SwissProt Accessions	O43776	Gene names	NARS, ASNS
Domain Architecture
Description	Asparaginyl-tRNA synthetase, cytoplasmic (EC 6.1.1.22) (Asparagine-- tRNA ligase) (AsnRS).

TAF9_HUMAN
NC score	0.014112 (rank : 159)	θ value	2.36792 (rank : 115)
Query Neighborhood Hits	167	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	Q16594, Q9BTS1	Gene names	TAF9, TAF2G, TAFII31
Domain Architecture
Description	Transcription initiation factor TFIID subunit 9 (Transcription initiation factor TFIID 31 kDa subunit) (TAFII-31) (TAFII-32) (TAFII32) (STAF31/32).

K1802_MOUSE
NC score	0.013439 (rank : 160)	θ value	1.81305 (rank : 100)
Query Neighborhood Hits	167	Target Neighborhood Hits	1596	Shared Neighborhood Hits	27
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

CCD46_MOUSE
NC score	0.012988 (rank : 161)	θ value	1.81305 (rank : 99)
Query Neighborhood Hits	167	Target Neighborhood Hits	1405	Shared Neighborhood Hits	30
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

GOGA5_MOUSE
NC score	0.012729 (rank : 162)	θ value	0.365318 (rank : 78)
Query Neighborhood Hits	167	Target Neighborhood Hits	1434	Shared Neighborhood Hits	25
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

TM108_MOUSE
NC score	0.012382 (rank : 163)	θ value	5.27518 (rank : 137)
Query Neighborhood Hits	167	Target Neighborhood Hits	336	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

IQGA2_HUMAN
NC score	0.012352 (rank : 164)	θ value	6.88961 (rank : 144)
Query Neighborhood Hits	167	Target Neighborhood Hits	200	Shared Neighborhood Hits	6
SwissProt Accessions	Q13576	Gene names	IQGAP2
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP2.

SSBP4_HUMAN
NC score	0.011750 (rank : 165)	θ value	3.0926 (rank : 122)
Query Neighborhood Hits	167	Target Neighborhood Hits	753	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

SAPS2_MOUSE
NC score	0.011557 (rank : 166)	θ value	5.27518 (rank : 134)
Query Neighborhood Hits	167	Target Neighborhood Hits	47	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R3Q2, Q9CXB7	Gene names	Saps2, Kiaa0685
Domain Architecture
Description	SAPS domain family member 2.

ANR15_HUMAN
NC score	0.009774 (rank : 167)	θ value	0.279714 (rank : 73)
Query Neighborhood Hits	167	Target Neighborhood Hits	478	Shared Neighborhood Hits	5
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

NOL11_MOUSE
NC score	0.009378 (rank : 168)	θ value	6.88961 (rank : 148)
Query Neighborhood Hits	167	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BJW5, Q8BGJ1, Q8R3Q3, Q99KA5	Gene names	Nol11
Domain Architecture	No domain graphic available
Description	Nucleolar protein 11.

DPOLZ_HUMAN
NC score	0.009260 (rank : 169)	θ value	6.88961 (rank : 140)
Query Neighborhood Hits	167	Target Neighborhood Hits	200	Shared Neighborhood Hits	7
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

SRBP1_MOUSE
NC score	0.009251 (rank : 170)	θ value	6.88961 (rank : 154)
Query Neighborhood Hits	167	Target Neighborhood Hits	384	Shared Neighborhood Hits	13
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

ANTR1_HUMAN
NC score	0.009226 (rank : 171)	θ value	6.88961 (rank : 138)
Query Neighborhood Hits	167	Target Neighborhood Hits	128	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H6X2, Q96P02, Q9NVP3	Gene names	ANTXR1, ATR, TEM8
Domain Architecture
Description	Anthrax toxin receptor 1 precursor (Tumor endothelial marker 8).

MAGE1_HUMAN
NC score	0.009040 (rank : 172)	θ value	6.88961 (rank : 147)
Query Neighborhood Hits	167	Target Neighborhood Hits	1389	Shared Neighborhood Hits	28
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

DTNA_MOUSE
NC score	0.008644 (rank : 173)	θ value	6.88961 (rank : 142)
Query Neighborhood Hits	167	Target Neighborhood Hits	264	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D2N4, P97319, Q61498, Q61499, Q9QZZ5, Q9WUL9, Q9WUM0	Gene names	Dtna, Dtn
Domain Architecture
Description	Dystrobrevin alpha (Alpha-dystrobrevin).

RPGR1_HUMAN
NC score	0.008634 (rank : 174)	θ value	5.27518 (rank : 133)
Query Neighborhood Hits	167	Target Neighborhood Hits	578	Shared Neighborhood Hits	13
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

CHD2_HUMAN
NC score	0.008456 (rank : 175)	θ value	2.36792 (rank : 109)
Query Neighborhood Hits	167	Target Neighborhood Hits	360	Shared Neighborhood Hits	10
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

DC1L1_HUMAN
NC score	0.008438 (rank : 176)	θ value	8.99809 (rank : 157)
Query Neighborhood Hits	167	Target Neighborhood Hits	39	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y6G9, Q53HC8, Q53HK7	Gene names	DYNC1LI1, DNCLI1
Domain Architecture	No domain graphic available
Description	Cytoplasmic dynein 1 light intermediate chain 1 (Dynein light intermediate chain 1, cytosolic) (Dynein light chain A) (DLC-A).

DC1L1_MOUSE
NC score	0.008272 (rank : 177)	θ value	8.99809 (rank : 158)
Query Neighborhood Hits	167	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R1Q8	Gene names	Dync1li1, Dncli1, Dnclic1
Domain Architecture	No domain graphic available
Description	Cytoplasmic dynein 1 light intermediate chain 1 (Dynein light intermediate chain 1, cytosolic) (Dynein light chain A) (DLC-A).

DTNA_HUMAN
NC score	0.007697 (rank : 178)	θ value	6.88961 (rank : 141)
Query Neighborhood Hits	167	Target Neighborhood Hits	295	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y4J8, O15332, O15333, O75697, Q13197, Q13198, Q13199, Q13498, Q13499, Q13500	Gene names	DTNA, DRP3
Domain Architecture
Description	Dystrobrevin alpha (Dystrobrevin-alpha) (Dystrophin-related protein 3).

TAF1C_MOUSE
NC score	0.007224 (rank : 179)	θ value	8.99809 (rank : 167)
Query Neighborhood Hits	167	Target Neighborhood Hits	54	Shared Neighborhood Hits	2
SwissProt Accessions	Q6PDZ2, P97359, Q3U3B6, Q8BN54	Gene names	Taf1c
Domain Architecture	No domain graphic available
Description	TATA box-binding protein-associated factor, RNA polymerase I, subunit C (TATA box-binding protein-associated factor 1C) (TBP-associated factor 1C) (TBP-associated factor RNA polymerase I 95 kDa) (TAFI95).

TEAD1_MOUSE
NC score	0.005808 (rank : 180)	θ value	5.27518 (rank : 136)
Query Neighborhood Hits	167	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	P30051	Gene names	Tead1, Tcf13, Tef-1, Tef1
Domain Architecture
Description	Transcriptional enhancer factor TEF-1 (TEA domain family member 1) (TEAD-1) (Protein GT-IIC) (Transcription factor 13) (NTEF-1).

RBCC1_MOUSE
NC score	0.005799 (rank : 181)	θ value	6.88961 (rank : 152)
Query Neighborhood Hits	167	Target Neighborhood Hits	1048	Shared Neighborhood Hits	16
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

MUCDL_HUMAN
NC score	0.004911 (rank : 182)	θ value	8.99809 (rank : 160)
Query Neighborhood Hits	167	Target Neighborhood Hits	777	Shared Neighborhood Hits	21
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

CP135_HUMAN
NC score	0.004710 (rank : 183)	θ value	5.27518 (rank : 126)
Query Neighborhood Hits	167	Target Neighborhood Hits	1290	Shared Neighborhood Hits	22
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

RBP2_HUMAN
NC score	0.004189 (rank : 184)	θ value	6.88961 (rank : 153)
Query Neighborhood Hits	167	Target Neighborhood Hits	249	Shared Neighborhood Hits	9
SwissProt Accessions	P49792, Q13074, Q15280, Q53TE2, Q59FH7	Gene names	RANBP2, NUP358
Domain Architecture
Description	Ran-binding protein 2 (RanBP2) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (358 kDa nucleoporin) (P270).

RPGF6_HUMAN
NC score	0.004132 (rank : 185)	θ value	8.99809 (rank : 166)
Query Neighborhood Hits	167	Target Neighborhood Hits	266	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

PTPRN_MOUSE
NC score	0.003783 (rank : 186)	θ value	8.99809 (rank : 164)
Query Neighborhood Hits	167	Target Neighborhood Hits	240	Shared Neighborhood Hits	9
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

NALD2_HUMAN
NC score	0.003536 (rank : 187)	θ value	8.99809 (rank : 161)
Query Neighborhood Hits	167	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y3Q0	Gene names	NAALAD2
Domain Architecture
Description	N-acetylated-alpha-linked acidic dipeptidase 2 (EC 3.4.17.21) (N- acetylated-alpha-linked acidic dipeptidase II) (NAALADase II).

ILRL2_MOUSE
NC score	0.003300 (rank : 188)	θ value	6.88961 (rank : 143)
Query Neighborhood Hits	167	Target Neighborhood Hits	158	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ERS7	Gene names	Il1rl2
Domain Architecture
Description	Interleukin-1 receptor-like 2 precursor (IL-1Rrp2).

KIF3B_HUMAN
NC score	0.003277 (rank : 189)	θ value	5.27518 (rank : 128)
Query Neighborhood Hits	167	Target Neighborhood Hits	540	Shared Neighborhood Hits	12
SwissProt Accessions	O15066	Gene names	KIF3B, KIAA0359
Domain Architecture
Description	Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B) (HH0048).

UACA_HUMAN
NC score	0.003258 (rank : 190)	θ value	6.88961 (rank : 155)
Query Neighborhood Hits	167	Target Neighborhood Hits	1622	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

NR4A2_MOUSE
NC score	0.003189 (rank : 191)	θ value	4.03905 (rank : 125)
Query Neighborhood Hits	167	Target Neighborhood Hits	121	Shared Neighborhood Hits	3
SwissProt Accessions	Q06219, O08690	Gene names	Nr4a2, Nurr1
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (NUR- related factor 1).

NR4A2_HUMAN
NC score	0.003187 (rank : 192)	θ value	4.03905 (rank : 124)
Query Neighborhood Hits	167	Target Neighborhood Hits	120	Shared Neighborhood Hits	3
SwissProt Accessions	P43354, Q16311	Gene names	NR4A2, NOT, NURR1, TINUR
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (Immediate-early response protein NOT) (Transcriptionally-inducible nuclear receptor).

KIF3B_MOUSE
NC score	0.002974 (rank : 193)	θ value	6.88961 (rank : 146)
Query Neighborhood Hits	167	Target Neighborhood Hits	533	Shared Neighborhood Hits	14
SwissProt Accessions	Q61771	Gene names	Kif3b
Domain Architecture
Description	Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B).

KI18A_MOUSE
NC score	0.002708 (rank : 194)	θ value	6.88961 (rank : 145)
Query Neighborhood Hits	167	Target Neighborhood Hits	212	Shared Neighborhood Hits	7
SwissProt Accessions	Q91WD7, Q3TP77, Q8BLL1	Gene names	Kif18a
Domain Architecture	No domain graphic available
Description	Kinesin family member 18A.

CP4FB_HUMAN
NC score	0.001977 (rank : 195)	θ value	3.0926 (rank : 117)
Query Neighborhood Hits	167	Target Neighborhood Hits	114	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HBI6, O75254, Q96AQ5	Gene names	CYP4F11
Domain Architecture
Description	Cytochrome P450 4F11 (EC 1.14.14.1) (CYPIVF11).

ADA12_MOUSE
NC score	0.001656 (rank : 196)	θ value	8.99809 (rank : 156)
Query Neighborhood Hits	167	Target Neighborhood Hits	474	Shared Neighborhood Hits	14
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

SLIK3_HUMAN
NC score	0.001613 (rank : 197)	θ value	5.27518 (rank : 135)
Query Neighborhood Hits	167	Target Neighborhood Hits	298	Shared Neighborhood Hits	7
SwissProt Accessions	O94933	Gene names	SLITRK3, KIAA0848
Domain Architecture	No domain graphic available
Description	SLIT and NTRK-like protein 3 precursor.

PTN13_HUMAN
NC score	0.001497 (rank : 198)	θ value	5.27518 (rank : 129)
Query Neighborhood Hits	167	Target Neighborhood Hits	471	Shared Neighborhood Hits	13
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

PGS1_HUMAN
NC score	-0.000270 (rank : 199)	θ value	8.99809 (rank : 162)
Query Neighborhood Hits	167	Target Neighborhood Hits	261	Shared Neighborhood Hits	4
SwissProt Accessions	P21810, P13247	Gene names	BGN
Domain Architecture
Description	Biglycan precursor (Bone/cartilage proteoglycan I) (PG-S1).

PGS1_MOUSE
NC score	-0.000313 (rank : 200)	θ value	8.99809 (rank : 163)
Query Neighborhood Hits	167	Target Neighborhood Hits	265	Shared Neighborhood Hits	4
SwissProt Accessions	P28653, Q61355	Gene names	Bgn
Domain Architecture
Description	Biglycan precursor (Bone/cartilage proteoglycan I) (PG-S1).

RIPK3_MOUSE
NC score	-0.003809 (rank : 201)	θ value	1.81305 (rank : 105)
Query Neighborhood Hits	167	Target Neighborhood Hits	867	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QZL0	Gene names	Ripk3, Rip3
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (mRIP3).

EVI1_MOUSE
NC score	-0.006036 (rank : 202)	θ value	8.99809 (rank : 159)
Query Neighborhood Hits	167	Target Neighborhood Hits	826	Shared Neighborhood Hits	6
SwissProt Accessions	P14404	Gene names	Evi1, Evi-1
Domain Architecture	No domain graphic available
Description	Ecotropic virus integration 1 site protein.