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Network neighborhood for query Sequence : DPOLZ_HUMAN

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DPOLZ_HUMAN
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DPOLZ_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	200	Target Neighborhood Hits	200	Shared Neighborhood Hits	200
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

DPOLZ_MOUSE
θ value	0 (rank : 2)	NC score	0.967263 (rank : 2)
Query Neighborhood Hits	200	Target Neighborhood Hits	169	Shared Neighborhood Hits	43
SwissProt Accessions	Q61493, Q9JMD6, Q9QWX6	Gene names	Rev3l, Polz, Sez4
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (Seizure-related protein 4).

DPOD1_MOUSE
θ value	2.64101e-84 (rank : 3)	NC score	0.804768 (rank : 3)
Query Neighborhood Hits	200	Target Neighborhood Hits	19	Shared Neighborhood Hits	6
SwissProt Accessions	P52431, O54883	Gene names	Pold1
Domain Architecture
Description	DNA polymerase delta catalytic subunit (EC 2.7.7.7).

DPOD1_HUMAN
θ value	1.71185e-83 (rank : 4)	NC score	0.803381 (rank : 4)
Query Neighborhood Hits	200	Target Neighborhood Hits	28	Shared Neighborhood Hits	6
SwissProt Accessions	P28340, Q8NER3, Q96H98	Gene names	POLD1, POLD
Domain Architecture
Description	DNA polymerase delta catalytic subunit (EC 2.7.7.7) (DNA polymerase subunit delta p125).

DPOLA_MOUSE
θ value	1.46948e-34 (rank : 5)	NC score	0.638419 (rank : 6)
Query Neighborhood Hits	200	Target Neighborhood Hits	56	Shared Neighborhood Hits	10
SwissProt Accessions	P33609	Gene names	Pola1, Pola
Domain Architecture
Description	DNA polymerase alpha catalytic subunit (EC 2.7.7.7).

DPOLA_HUMAN
θ value	2.12192e-33 (rank : 6)	NC score	0.638448 (rank : 5)
Query Neighborhood Hits	200	Target Neighborhood Hits	41	Shared Neighborhood Hits	6
SwissProt Accessions	P09884, Q86UQ7	Gene names	POLA1, POLA
Domain Architecture
Description	DNA polymerase alpha catalytic subunit (EC 2.7.7.7).

SEMG2_HUMAN
θ value	0.00134147 (rank : 7)	NC score	0.081609 (rank : 11)
Query Neighborhood Hits	200	Target Neighborhood Hits	251	Shared Neighborhood Hits	31
SwissProt Accessions	Q02383, Q6X2M6	Gene names	SEMG2
Domain Architecture
Description	Semenogelin-2 precursor (Semenogelin II) (SGII).

SGP50_MOUSE
θ value	0.00869519 (rank : 8)	NC score	0.136928 (rank : 7)
Query Neighborhood Hits	200	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q02596	Gene names	Glycam1
Domain Architecture
Description	Sulfated 50 kDa glycoprotein precursor (SGP50) (Endothelial ligand FOR L-selectin) (Glycosylation-dependent cell adhesion molecule 1) (GlyCAM-1) (MC26).

MYCB2_HUMAN
θ value	0.0113563 (rank : 9)	NC score	0.048561 (rank : 22)
Query Neighborhood Hits	200	Target Neighborhood Hits	390	Shared Neighborhood Hits	22
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

DSPP_HUMAN
θ value	0.0193708 (rank : 10)	NC score	0.081797 (rank : 10)
Query Neighborhood Hits	200	Target Neighborhood Hits	645	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

PCLO_HUMAN
θ value	0.0252991 (rank : 11)	NC score	0.053434 (rank : 18)
Query Neighborhood Hits	200	Target Neighborhood Hits	2046	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

LYRIC_HUMAN
θ value	0.0431538 (rank : 12)	NC score	0.083891 (rank : 8)
Query Neighborhood Hits	200	Target Neighborhood Hits	99	Shared Neighborhood Hits	16
SwissProt Accessions	Q86UE4, Q6PK07, Q8TCX3	Gene names	MTDH, AEG1, LYRIC
Domain Architecture	No domain graphic available
Description	Protein LYRIC (Lysine-rich CEACAM1 co-isolated protein) (3D3/lyric) (Metastasis adhesion protein) (Metadherin) (Astrocyte elevated gene-1 protein) (AEG-1).

PCLO_MOUSE
θ value	0.0431538 (rank : 13)	NC score	0.043324 (rank : 28)
Query Neighborhood Hits	200	Target Neighborhood Hits	2275	Shared Neighborhood Hits	70
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

E41L2_HUMAN
θ value	0.0563607 (rank : 14)	NC score	0.026195 (rank : 76)
Query Neighborhood Hits	200	Target Neighborhood Hits	287	Shared Neighborhood Hits	24
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

LYRIC_MOUSE
θ value	0.0563607 (rank : 15)	NC score	0.082754 (rank : 9)
Query Neighborhood Hits	200	Target Neighborhood Hits	126	Shared Neighborhood Hits	14
SwissProt Accessions	Q80WJ7, Q3U9F8, Q3UAQ8, Q8BN67, Q8CBT9, Q8CDL0, Q8CGI7, Q9D052	Gene names	Mtdh, Lyric
Domain Architecture	No domain graphic available
Description	Protein LYRIC (Lysine-rich CEACAM1 co-isolated protein) (3D3/LYRIC) (Metastasis adhesion protein) (Metadherin).

RSF1_HUMAN
θ value	0.0563607 (rank : 16)	NC score	0.061996 (rank : 14)
Query Neighborhood Hits	200	Target Neighborhood Hits	539	Shared Neighborhood Hits	46
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

EMSY_HUMAN
θ value	0.0736092 (rank : 17)	NC score	0.052244 (rank : 19)
Query Neighborhood Hits	200	Target Neighborhood Hits	296	Shared Neighborhood Hits	16
SwissProt Accessions	Q7Z589, Q4G109, Q8NBU6, Q8TE50, Q9H8I9, Q9NRH0	Gene names	EMSY, C11orf30
Domain Architecture
Description	Protein EMSY.

MYST4_HUMAN
θ value	0.0961366 (rank : 18)	NC score	0.035987 (rank : 47)
Query Neighborhood Hits	200	Target Neighborhood Hits	671	Shared Neighborhood Hits	48
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

NKTR_HUMAN
θ value	0.163984 (rank : 19)	NC score	0.034399 (rank : 51)
Query Neighborhood Hits	200	Target Neighborhood Hits	658	Shared Neighborhood Hits	52
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

ARFG3_HUMAN
θ value	0.279714 (rank : 20)	NC score	0.035235 (rank : 49)
Query Neighborhood Hits	200	Target Neighborhood Hits	56	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NP61, Q9BSC6, Q9H9J0, Q9NT10, Q9NUP5, Q9Y4V3, Q9Y4V4	Gene names	ARFGAP3, ARFGAP1
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

CAC1D_HUMAN
θ value	0.279714 (rank : 21)	NC score	0.014932 (rank : 142)
Query Neighborhood Hits	200	Target Neighborhood Hits	118	Shared Neighborhood Hits	4
SwissProt Accessions	Q01668, Q13916, Q13931	Gene names	CACNA1D, CACH3, CACN4, CACNL1A2, CCHL1A2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1D (Voltage- gated calcium channel subunit alpha Cav1.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 2).

MYO5B_HUMAN
θ value	0.279714 (rank : 22)	NC score	0.016796 (rank : 126)
Query Neighborhood Hits	200	Target Neighborhood Hits	911	Shared Neighborhood Hits	34
SwissProt Accessions	Q9ULV0	Gene names	MYO5B, KIAA1119
Domain Architecture
Description	Myosin-5B (Myosin Vb).

PO121_MOUSE
θ value	0.279714 (rank : 23)	NC score	0.039021 (rank : 35)
Query Neighborhood Hits	200	Target Neighborhood Hits	345	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

FYCO1_HUMAN
θ value	0.365318 (rank : 24)	NC score	0.020648 (rank : 105)
Query Neighborhood Hits	200	Target Neighborhood Hits	1149	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

UBP1_HUMAN
θ value	0.365318 (rank : 25)	NC score	0.058598 (rank : 16)
Query Neighborhood Hits	200	Target Neighborhood Hits	259	Shared Neighborhood Hits	20
SwissProt Accessions	O94782, Q9UFR0, Q9UNJ3	Gene names	USP1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.1.2.15) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) (Deubiquitinating enzyme 1) (hUBP).

ADNP_HUMAN
θ value	0.47712 (rank : 26)	NC score	0.047192 (rank : 24)
Query Neighborhood Hits	200	Target Neighborhood Hits	265	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H2P0, O94881, Q9UG34	Gene names	ADNP, KIAA0784
Domain Architecture
Description	Activity-dependent neuroprotector (Activity-dependent neuroprotective protein).

BICD2_MOUSE
θ value	0.47712 (rank : 27)	NC score	0.022335 (rank : 100)
Query Neighborhood Hits	200	Target Neighborhood Hits	864	Shared Neighborhood Hits	34
SwissProt Accessions	Q921C5, Q80TU1, Q8BTE3, Q9DCL3	Gene names	Bicd2, Kiaa0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

CEP35_HUMAN
θ value	0.47712 (rank : 28)	NC score	0.036872 (rank : 42)
Query Neighborhood Hits	200	Target Neighborhood Hits	811	Shared Neighborhood Hits	48
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

RLF_HUMAN
θ value	0.47712 (rank : 29)	NC score	0.011910 (rank : 161)
Query Neighborhood Hits	200	Target Neighborhood Hits	775	Shared Neighborhood Hits	18
SwissProt Accessions	Q13129, Q9NU60	Gene names	RLF
Domain Architecture	No domain graphic available
Description	Zinc finger protein Rlf (Rearranged L-myc fusion gene protein) (Zn-15- related protein).

TSH2_MOUSE
θ value	0.47712 (rank : 30)	NC score	0.022973 (rank : 95)
Query Neighborhood Hits	200	Target Neighborhood Hits	467	Shared Neighborhood Hits	12
SwissProt Accessions	Q68FE9, Q5DTF1, Q6AXH5, Q9JL71	Gene names	Tshz2, Kiaa4248, Sdccag33l, Tsh2, Zfp218, Znf218
Domain Architecture	No domain graphic available
Description	Teashirt homolog 2 (Zinc finger protein 218) (SDCCAG33-like protein).

ERCC6_HUMAN
θ value	0.62314 (rank : 31)	NC score	0.017379 (rank : 122)
Query Neighborhood Hits	200	Target Neighborhood Hits	247	Shared Neighborhood Hits	17
SwissProt Accessions	Q03468	Gene names	ERCC6, CSB
Domain Architecture
Description	DNA excision repair protein ERCC-6 (EC 3.6.1.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB).

HAP1_HUMAN
θ value	0.62314 (rank : 32)	NC score	0.027508 (rank : 70)
Query Neighborhood Hits	200	Target Neighborhood Hits	606	Shared Neighborhood Hits	22
SwissProt Accessions	P54257, O75358, Q9H4G3, Q9HA98, Q9NY90	Gene names	HAP1, HLP1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1) (Neuroan 1).

LIPA2_HUMAN
θ value	0.62314 (rank : 33)	NC score	0.023232 (rank : 93)
Query Neighborhood Hits	200	Target Neighborhood Hits	1044	Shared Neighborhood Hits	33
SwissProt Accessions	O75334	Gene names	PPFIA2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

TTC28_HUMAN
θ value	0.62314 (rank : 34)	NC score	0.027040 (rank : 73)
Query Neighborhood Hits	200	Target Neighborhood Hits	271	Shared Neighborhood Hits	17
SwissProt Accessions	Q96AY4, O95928, O95929, Q9NTE4, Q9UG31, Q9UGG5, Q9UPV8, Q9Y3S5	Gene names	TTC28, KIAA1043
Domain Architecture
Description	Tetratricopeptide repeat protein 28 (TPR repeat protein 28).

ANK3_HUMAN
θ value	0.813845 (rank : 35)	NC score	0.013873 (rank : 151)
Query Neighborhood Hits	200	Target Neighborhood Hits	853	Shared Neighborhood Hits	50
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

FNBP2_HUMAN
θ value	0.813845 (rank : 36)	NC score	0.017913 (rank : 121)
Query Neighborhood Hits	200	Target Neighborhood Hits	432	Shared Neighborhood Hits	16
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

OTU6B_MOUSE
θ value	0.813845 (rank : 37)	NC score	0.028630 (rank : 68)
Query Neighborhood Hits	200	Target Neighborhood Hits	202	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K2H2	Gene names	Otud6b
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 6B.

EXOC8_MOUSE
θ value	1.06291 (rank : 38)	NC score	0.030550 (rank : 64)
Query Neighborhood Hits	200	Target Neighborhood Hits	43	Shared Neighborhood Hits	5
SwissProt Accessions	Q6PGF7	Gene names	Exoc8
Domain Architecture	No domain graphic available
Description	Exocyst complex component 8 (Exocyst complex 84 kDa subunit).

FA8_MOUSE
θ value	1.06291 (rank : 39)	NC score	0.015808 (rank : 135)
Query Neighborhood Hits	200	Target Neighborhood Hits	100	Shared Neighborhood Hits	6
SwissProt Accessions	Q06194	Gene names	F8, Cf8, F8c
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component).

LIPA2_MOUSE
θ value	1.06291 (rank : 40)	NC score	0.022229 (rank : 101)
Query Neighborhood Hits	200	Target Neighborhood Hits	1282	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

MYH8_HUMAN
θ value	1.06291 (rank : 41)	NC score	0.016947 (rank : 124)
Query Neighborhood Hits	200	Target Neighborhood Hits	1610	Shared Neighborhood Hits	62
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

POTE8_HUMAN
θ value	1.06291 (rank : 42)	NC score	0.011151 (rank : 165)
Query Neighborhood Hits	200	Target Neighborhood Hits	337	Shared Neighborhood Hits	8
SwissProt Accessions	Q6S8J7, Q6S8J6	Gene names	POTE8
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 8.

SNX11_MOUSE
θ value	1.06291 (rank : 43)	NC score	0.040217 (rank : 34)
Query Neighborhood Hits	200	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	Q91WL6, Q3V3A6	Gene names	Snx11
Domain Architecture	No domain graphic available
Description	Sorting nexin-11.

CCNT2_HUMAN
θ value	1.38821 (rank : 44)	NC score	0.036845 (rank : 43)
Query Neighborhood Hits	200	Target Neighborhood Hits	84	Shared Neighborhood Hits	12
SwissProt Accessions	O60583, O60582, Q5I1Y0	Gene names	CCNT2
Domain Architecture
Description	Cyclin-T2 (CycT2).

PRG4_MOUSE
θ value	1.38821 (rank : 45)	NC score	0.025856 (rank : 77)
Query Neighborhood Hits	200	Target Neighborhood Hits	624	Shared Neighborhood Hits	38
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

UBP2L_HUMAN
θ value	1.38821 (rank : 46)	NC score	0.046856 (rank : 26)
Query Neighborhood Hits	200	Target Neighborhood Hits	170	Shared Neighborhood Hits	18
SwissProt Accessions	Q14157, Q5VU75, Q5VU76, Q9BTU3, Q9UGL5	Gene names	UBAP2L, KIAA0144, NICE4
Domain Architecture
Description	Ubiquitin-associated protein 2-like (Protein NICE-4).

CNOT4_MOUSE
θ value	1.81305 (rank : 47)	NC score	0.025476 (rank : 82)
Query Neighborhood Hits	200	Target Neighborhood Hits	277	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BT14, Q8CCR4, Q9CV74, Q9Z1D0	Gene names	Cnot4, Not4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

FSD1L_MOUSE
θ value	1.81305 (rank : 48)	NC score	0.036061 (rank : 46)
Query Neighborhood Hits	200	Target Neighborhood Hits	78	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BYN5, Q3USW7	Gene names	Fsd1l, Ccdc10, Csdufd1, Fsd1nl
Domain Architecture	No domain graphic available
Description	FSD1-like protein (FSD1 N-terminal-like protein) (Coiled-coil domain- containing protein 10).

GDE_HUMAN
θ value	1.81305 (rank : 49)	NC score	0.031972 (rank : 59)
Query Neighborhood Hits	200	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	P35573, P78354, P78544, Q9UF08	Gene names	AGL, GDE
Domain Architecture
Description	Glycogen debranching enzyme (Glycogen debrancher) [Includes: 4-alpha- glucanotransferase (EC 2.4.1.25) (Oligo-1,4-1,4-glucantransferase); Amylo-alpha-1,6-glucosidase (EC 3.2.1.33) (Amylo-1,6-glucosidase) (Dextrin 6-alpha-D-glucosidase)].

GFPT1_HUMAN
θ value	1.81305 (rank : 50)	NC score	0.025028 (rank : 85)
Query Neighborhood Hits	200	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q06210, Q9BXF8	Gene names	GFPT1, GFAT, GFPT
Domain Architecture
Description	Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1 (EC 2.6.1.16) (Hexosephosphate aminotransferase 1) (D-fructose-6- phosphate amidotransferase 1) (GFAT 1) (GFAT1).

LEO1_HUMAN
θ value	1.81305 (rank : 51)	NC score	0.038211 (rank : 39)
Query Neighborhood Hits	200	Target Neighborhood Hits	958	Shared Neighborhood Hits	58
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

NUP50_HUMAN
θ value	1.81305 (rank : 52)	NC score	0.030300 (rank : 65)
Query Neighborhood Hits	200	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UKX7, O75644, Q9NPM9, Q9NPR6, Q9P1K5	Gene names	NUP50, NPAP60L
Domain Architecture
Description	Nucleoporin 50 kDa (Nuclear pore-associated protein 60 kDa-like).

PDLI1_HUMAN
θ value	1.81305 (rank : 53)	NC score	0.034973 (rank : 50)
Query Neighborhood Hits	200	Target Neighborhood Hits	242	Shared Neighborhood Hits	3
SwissProt Accessions	O00151, Q5VZH5, Q9BPZ9	Gene names	PDLIM1, CLIM1, CLP36
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

RING2_HUMAN
θ value	1.81305 (rank : 54)	NC score	0.025220 (rank : 84)
Query Neighborhood Hits	200	Target Neighborhood Hits	201	Shared Neighborhood Hits	7
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

RING2_MOUSE
θ value	1.81305 (rank : 55)	NC score	0.025305 (rank : 83)
Query Neighborhood Hits	200	Target Neighborhood Hits	199	Shared Neighborhood Hits	7
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

RRP5_HUMAN
θ value	1.81305 (rank : 56)	NC score	0.043630 (rank : 27)
Query Neighborhood Hits	200	Target Neighborhood Hits	291	Shared Neighborhood Hits	29
SwissProt Accessions	Q14690, Q86VQ8	Gene names	PDCD11, KIAA0185
Domain Architecture
Description	RRP5 protein homolog (Programmed cell death protein 11).

CBP_HUMAN
θ value	2.36792 (rank : 57)	NC score	0.018567 (rank : 117)
Query Neighborhood Hits	200	Target Neighborhood Hits	941	Shared Neighborhood Hits	34
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CENPE_HUMAN
θ value	2.36792 (rank : 58)	NC score	0.025593 (rank : 80)
Query Neighborhood Hits	200	Target Neighborhood Hits	2060	Shared Neighborhood Hits	73
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

CLMN_MOUSE
θ value	2.36792 (rank : 59)	NC score	0.012175 (rank : 160)
Query Neighborhood Hits	200	Target Neighborhood Hits	180	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C5W0, Q91V71, Q91XT7, Q91XT8, Q91XU9	Gene names	Clmn
Domain Architecture
Description	Calmin.

ELOA1_MOUSE
θ value	2.36792 (rank : 60)	NC score	0.022690 (rank : 98)
Query Neighborhood Hits	200	Target Neighborhood Hits	152	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CB77, Q80VB2, Q9R0Q5	Gene names	Tceb3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

GFPT1_MOUSE
θ value	2.36792 (rank : 61)	NC score	0.024050 (rank : 87)
Query Neighborhood Hits	200	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	P47856, Q91XG9, Q99LP7, Q99MJ4	Gene names	Gfpt1, Gfpt
Domain Architecture
Description	Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1 (EC 2.6.1.16) (Hexosephosphate aminotransferase 1) (D-fructose-6- phosphate amidotransferase 1) (GFAT 1) (GFAT1).

RBBP6_HUMAN
θ value	2.36792 (rank : 62)	NC score	0.047706 (rank : 23)
Query Neighborhood Hits	200	Target Neighborhood Hits	1135	Shared Neighborhood Hits	66
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RFC1_MOUSE
θ value	2.36792 (rank : 63)	NC score	0.024842 (rank : 86)
Query Neighborhood Hits	200	Target Neighborhood Hits	290	Shared Neighborhood Hits	24
SwissProt Accessions	P35601	Gene names	Rfc1, Ibf-1, Recc1
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (A1-P145) (Differentiation- specific element-binding protein) (ISRE-binding protein).

SENP6_HUMAN
θ value	2.36792 (rank : 64)	NC score	0.038915 (rank : 36)
Query Neighborhood Hits	200	Target Neighborhood Hits	69	Shared Neighborhood Hits	8
SwissProt Accessions	Q9GZR1, O94891, Q8TBY4, Q9UJV5	Gene names	SENP6, KIAA0797, SSP1, SUSP1
Domain Architecture
Description	Sentrin-specific protease 6 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP6) (SUMO-1-specific protease 1).

SMC4_MOUSE
θ value	2.36792 (rank : 65)	NC score	0.016405 (rank : 130)
Query Neighborhood Hits	200	Target Neighborhood Hits	830	Shared Neighborhood Hits	25
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

SNCAP_HUMAN
θ value	2.36792 (rank : 66)	NC score	0.018449 (rank : 119)
Query Neighborhood Hits	200	Target Neighborhood Hits	313	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y6H5	Gene names	SNCAIP
Domain Architecture
Description	Synphilin-1 (Alpha-synuclein-interacting protein).

SRBS1_HUMAN
θ value	2.36792 (rank : 67)	NC score	0.019428 (rank : 111)
Query Neighborhood Hits	200	Target Neighborhood Hits	396	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SRRM2_HUMAN
θ value	2.36792 (rank : 68)	NC score	0.031057 (rank : 61)
Query Neighborhood Hits	200	Target Neighborhood Hits	1296	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

TGON2_HUMAN
θ value	2.36792 (rank : 69)	NC score	0.040867 (rank : 32)
Query Neighborhood Hits	200	Target Neighborhood Hits	1037	Shared Neighborhood Hits	63
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

UBP2L_MOUSE
θ value	2.36792 (rank : 70)	NC score	0.046896 (rank : 25)
Query Neighborhood Hits	200	Target Neighborhood Hits	173	Shared Neighborhood Hits	21
SwissProt Accessions	Q80X50, Q8BIT6, Q8BIW4, Q8BJ01, Q8CIG7, Q8K102, Q9CRT6	Gene names	Ubap2l
Domain Architecture	No domain graphic available
Description	Ubiquitin-associated protein 2-like.

ZFY19_HUMAN
θ value	2.36792 (rank : 71)	NC score	0.022634 (rank : 99)
Query Neighborhood Hits	200	Target Neighborhood Hits	206	Shared Neighborhood Hits	6
SwissProt Accessions	Q96K21, Q86WC2, Q8WU96	Gene names	ZFYVE19, MPFYVE
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19 (MLL partner containing FYVE domain).

AF9_HUMAN
θ value	3.0926 (rank : 72)	NC score	0.035517 (rank : 48)
Query Neighborhood Hits	200	Target Neighborhood Hits	202	Shared Neighborhood Hits	24
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

CNOT2_MOUSE
θ value	3.0926 (rank : 73)	NC score	0.026912 (rank : 75)
Query Neighborhood Hits	200	Target Neighborhood Hits	39	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C5L3, Q3UE39, Q80YA5, Q9D0P1	Gene names	Cnot2
Domain Architecture
Description	CCR4-NOT transcription complex subunit 2 (CCR4-associated factor 2).

DMP1_HUMAN
θ value	3.0926 (rank : 74)	NC score	0.042661 (rank : 31)
Query Neighborhood Hits	200	Target Neighborhood Hits	491	Shared Neighborhood Hits	45
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

FLIP1_HUMAN
θ value	3.0926 (rank : 75)	NC score	0.014473 (rank : 146)
Query Neighborhood Hits	200	Target Neighborhood Hits	1405	Shared Neighborhood Hits	43
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

GON4L_HUMAN
θ value	3.0926 (rank : 76)	NC score	0.022773 (rank : 96)
Query Neighborhood Hits	200	Target Neighborhood Hits	555	Shared Neighborhood Hits	33
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

HRX_HUMAN
θ value	3.0926 (rank : 77)	NC score	0.032875 (rank : 56)
Query Neighborhood Hits	200	Target Neighborhood Hits	825	Shared Neighborhood Hits	41
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

K1718_HUMAN
θ value	3.0926 (rank : 78)	NC score	0.012848 (rank : 156)
Query Neighborhood Hits	200	Target Neighborhood Hits	114	Shared Neighborhood Hits	5
SwissProt Accessions	Q6ZMT4, Q6MZL8, Q9C0E5	Gene names	KIAA1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

MATR3_MOUSE
θ value	3.0926 (rank : 79)	NC score	0.033224 (rank : 55)
Query Neighborhood Hits	200	Target Neighborhood Hits	321	Shared Neighborhood Hits	27
SwissProt Accessions	Q8K310	Gene names	Matr3
Domain Architecture	No domain graphic available
Description	Matrin-3.

MYT1_MOUSE
θ value	3.0926 (rank : 80)	NC score	0.017050 (rank : 123)
Query Neighborhood Hits	200	Target Neighborhood Hits	385	Shared Neighborhood Hits	25
SwissProt Accessions	Q8CFC2, O08995, Q8CFH1	Gene names	Myt1, Kiaa0835, Nzf2
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1 (MyT1) (Neural zinc finger factor 2) (NZF-2).

NCOR2_MOUSE
θ value	3.0926 (rank : 81)	NC score	0.018457 (rank : 118)
Query Neighborhood Hits	200	Target Neighborhood Hits	790	Shared Neighborhood Hits	38
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

NFH_HUMAN
θ value	3.0926 (rank : 82)	NC score	0.019200 (rank : 112)
Query Neighborhood Hits	200	Target Neighborhood Hits	1242	Shared Neighborhood Hits	64
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PTN13_HUMAN
θ value	3.0926 (rank : 83)	NC score	0.011066 (rank : 166)
Query Neighborhood Hits	200	Target Neighborhood Hits	471	Shared Neighborhood Hits	25
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

SYCP1_MOUSE
θ value	3.0926 (rank : 84)	NC score	0.018608 (rank : 116)
Query Neighborhood Hits	200	Target Neighborhood Hits	1456	Shared Neighborhood Hits	58
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

THSD1_HUMAN
θ value	3.0926 (rank : 85)	NC score	0.016759 (rank : 127)
Query Neighborhood Hits	200	Target Neighborhood Hits	136	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NS62, Q6P3U1, Q6UXZ2	Gene names	THSD1, TMTSP
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

TRDN_HUMAN
θ value	3.0926 (rank : 86)	NC score	0.037360 (rank : 41)
Query Neighborhood Hits	200	Target Neighborhood Hits	542	Shared Neighborhood Hits	39
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

WDHD1_MOUSE
θ value	3.0926 (rank : 87)	NC score	0.016350 (rank : 131)
Query Neighborhood Hits	200	Target Neighborhood Hits	414	Shared Neighborhood Hits	21
SwissProt Accessions	P59328, Q6P408	Gene names	Wdhd1, And1
Domain Architecture	No domain graphic available
Description	WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA- binding protein 1) (And-1).

CLUA1_MOUSE
θ value	4.03905 (rank : 88)	NC score	0.023595 (rank : 89)
Query Neighborhood Hits	200	Target Neighborhood Hits	261	Shared Neighborhood Hits	14
SwissProt Accessions	Q8R3P7, Q6P3Y8	Gene names	Cluap1
Domain Architecture	No domain graphic available
Description	Clusterin-associated protein 1.

DNJC1_MOUSE
θ value	4.03905 (rank : 89)	NC score	0.011529 (rank : 164)
Query Neighborhood Hits	200	Target Neighborhood Hits	129	Shared Neighborhood Hits	7
SwissProt Accessions	Q61712	Gene names	Dnajc1, Dnajl1, Mtj1
Domain Architecture
Description	DnaJ homolog subfamily C member 1 (DnaJ protein homolog MTJ1).

EMSY_MOUSE
θ value	4.03905 (rank : 90)	NC score	0.036506 (rank : 45)
Query Neighborhood Hits	200	Target Neighborhood Hits	294	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BMB0, Q5FWK5, Q80XU1, Q8VDW9	Gene names	Emsy
Domain Architecture
Description	Protein EMSY.

FOXJ3_HUMAN
θ value	4.03905 (rank : 91)	NC score	0.007562 (rank : 180)
Query Neighborhood Hits	200	Target Neighborhood Hits	177	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UPW0, Q9NSS7	Gene names	FOXJ3, KIAA1041
Domain Architecture
Description	Forkhead box protein J3.

FSD1L_HUMAN
θ value	4.03905 (rank : 92)	NC score	0.029716 (rank : 66)
Query Neighborhood Hits	200	Target Neighborhood Hits	57	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BXM9, Q5T880	Gene names	FSD1L, CCDC10, CSDUFD1, FSD1NL
Domain Architecture	No domain graphic available
Description	FSD1-like protein (FSD1 N-terminal-like protein) (Coiled-coil domain- containing protein 10).

GP179_HUMAN
θ value	4.03905 (rank : 93)	NC score	0.032848 (rank : 57)
Query Neighborhood Hits	200	Target Neighborhood Hits	372	Shared Neighborhood Hits	19
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

H6ST2_HUMAN
θ value	4.03905 (rank : 94)	NC score	0.013929 (rank : 149)
Query Neighborhood Hits	200	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q96MM7, Q4VC07, Q6PIC4, Q86SM9, Q8N3T4, Q8NBN4, Q96SJ4	Gene names	HS6ST2
Domain Architecture	No domain graphic available
Description	Heparan-sulfate 6-O-sulfotransferase 2 (EC 2.8.2.-) (HS6ST-2).

M4K4_HUMAN
θ value	4.03905 (rank : 95)	NC score	0.003174 (rank : 194)
Query Neighborhood Hits	200	Target Neighborhood Hits	1589	Shared Neighborhood Hits	39
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

MBD5_HUMAN
θ value	4.03905 (rank : 96)	NC score	0.023510 (rank : 91)
Query Neighborhood Hits	200	Target Neighborhood Hits	176	Shared Neighborhood Hits	13
SwissProt Accessions	Q9P267, Q9NUV6	Gene names	MBD5, KIAA1461
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 5 (Methyl-CpG-binding protein MBD5).

OSBL1_HUMAN
θ value	4.03905 (rank : 97)	NC score	0.006968 (rank : 186)
Query Neighborhood Hits	200	Target Neighborhood Hits	368	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

P80C_HUMAN
θ value	4.03905 (rank : 98)	NC score	0.038769 (rank : 37)
Query Neighborhood Hits	200	Target Neighborhood Hits	73	Shared Neighborhood Hits	8
SwissProt Accessions	P38432	Gene names	COIL, CLN80
Domain Architecture	No domain graphic available
Description	Coilin (p80).

RBBP6_MOUSE
θ value	4.03905 (rank : 99)	NC score	0.048906 (rank : 21)
Query Neighborhood Hits	200	Target Neighborhood Hits	1014	Shared Neighborhood Hits	67
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

REV1_HUMAN
θ value	4.03905 (rank : 100)	NC score	0.015470 (rank : 136)
Query Neighborhood Hits	200	Target Neighborhood Hits	56	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBZ9, O95941, Q9C0J4, Q9NUP2	Gene names	REV1L, REV1
Domain Architecture	No domain graphic available
Description	DNA repair protein REV1 (EC 2.7.7.-) (Rev1-like terminal deoxycytidyl transferase) (Alpha integrin-binding protein 80) (AIBP80).

RGP2_HUMAN
θ value	4.03905 (rank : 101)	NC score	0.014581 (rank : 145)
Query Neighborhood Hits	200	Target Neighborhood Hits	60	Shared Neighborhood Hits	7
SwissProt Accessions	P47736	Gene names	RAP1GAP, RAP1GA1
Domain Architecture
Description	Rap1 GTPase-activating protein 1 (Rap1GAP).

RRBP1_MOUSE
θ value	4.03905 (rank : 102)	NC score	0.023235 (rank : 92)
Query Neighborhood Hits	200	Target Neighborhood Hits	1650	Shared Neighborhood Hits	73
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

SFR11_HUMAN
θ value	4.03905 (rank : 103)	NC score	0.033758 (rank : 53)
Query Neighborhood Hits	200	Target Neighborhood Hits	246	Shared Neighborhood Hits	24
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

TP53B_MOUSE
θ value	4.03905 (rank : 104)	NC score	0.042670 (rank : 30)
Query Neighborhood Hits	200	Target Neighborhood Hits	644	Shared Neighborhood Hits	49
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TXND2_MOUSE
θ value	4.03905 (rank : 105)	NC score	0.038592 (rank : 38)
Query Neighborhood Hits	200	Target Neighborhood Hits	828	Shared Neighborhood Hits	62
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

ZEP1_HUMAN
θ value	4.03905 (rank : 106)	NC score	0.005896 (rank : 189)
Query Neighborhood Hits	200	Target Neighborhood Hits	1036	Shared Neighborhood Hits	29
SwissProt Accessions	P15822, Q14122	Gene names	HIVEP1, ZNF40
Domain Architecture	No domain graphic available
Description	Zinc finger protein 40 (Human immunodeficiency virus type I enhancer- binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1).

APC_MOUSE
θ value	5.27518 (rank : 107)	NC score	0.018756 (rank : 114)
Query Neighborhood Hits	200	Target Neighborhood Hits	441	Shared Neighborhood Hits	31
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

ATS8_HUMAN
θ value	5.27518 (rank : 108)	NC score	0.003837 (rank : 192)
Query Neighborhood Hits	200	Target Neighborhood Hits	145	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UP79, Q9NZS0	Gene names	ADAMTS8, METH2
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2) (METH- 8).

CNOT2_HUMAN
θ value	5.27518 (rank : 109)	NC score	0.025673 (rank : 79)
Query Neighborhood Hits	200	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NZN8, Q9H3E0, Q9NSX5, Q9NWR6, Q9P028	Gene names	CNOT2, CDC36, NOT2
Domain Architecture
Description	CCR4-NOT transcription complex subunit 2 (CCR4-associated factor 2).

CS007_MOUSE
θ value	5.27518 (rank : 110)	NC score	0.016263 (rank : 132)
Query Neighborhood Hits	200	Target Neighborhood Hits	464	Shared Neighborhood Hits	21
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

FRM4B_MOUSE
θ value	5.27518 (rank : 111)	NC score	0.013921 (rank : 150)
Query Neighborhood Hits	200	Target Neighborhood Hits	109	Shared Neighborhood Hits	12
SwissProt Accessions	Q920B0, Q3V1S1, Q9ESP9	Gene names	Frmd4b
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1) (Golgi- associated band 4.1-like protein) (GOBLIN).

KCTD5_HUMAN
θ value	5.27518 (rank : 112)	NC score	0.015103 (rank : 138)
Query Neighborhood Hits	200	Target Neighborhood Hits	66	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NXV2	Gene names	KCTD5
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD5.

KCTD5_MOUSE
θ value	5.27518 (rank : 113)	NC score	0.015087 (rank : 140)
Query Neighborhood Hits	200	Target Neighborhood Hits	64	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VC57	Gene names	Kctd5
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD5.

KIF1B_HUMAN
θ value	5.27518 (rank : 114)	NC score	0.007643 (rank : 179)
Query Neighborhood Hits	200	Target Neighborhood Hits	178	Shared Neighborhood Hits	6
SwissProt Accessions	O60333, Q96Q94, Q9BV80, Q9P280	Gene names	KIF1B, KIAA0591, KIAA1448
Domain Architecture
Description	Kinesin-like protein KIF1B (Klp).

MAT1_HUMAN
θ value	5.27518 (rank : 115)	NC score	0.023160 (rank : 94)
Query Neighborhood Hits	200	Target Neighborhood Hits	179	Shared Neighborhood Hits	10
SwissProt Accessions	P51948, Q15817	Gene names	MNAT1, CAP35, MAT1, RNF66
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35) (Cyclin G1-interacting protein) (RING finger protein 66).

MATR3_HUMAN
θ value	5.27518 (rank : 116)	NC score	0.029682 (rank : 67)
Query Neighborhood Hits	200	Target Neighborhood Hits	325	Shared Neighborhood Hits	27
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

MEPE_HUMAN
θ value	5.27518 (rank : 117)	NC score	0.031752 (rank : 60)
Query Neighborhood Hits	200	Target Neighborhood Hits	105	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NQ76	Gene names	MEPE
Domain Architecture
Description	Matrix extracellular phosphoglycoprotein precursor (Osteoblast/osteocyte factor 45) (OF45).

MORC3_HUMAN
θ value	5.27518 (rank : 118)	NC score	0.014609 (rank : 144)
Query Neighborhood Hits	200	Target Neighborhood Hits	489	Shared Neighborhood Hits	23
SwissProt Accessions	Q14149, Q9UEZ2	Gene names	MORC3, KIAA0136, ZCWCC3
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 3 (Zinc finger CW-type coiled- coil domain protein 3).

NPBL_MOUSE
θ value	5.27518 (rank : 119)	NC score	0.037401 (rank : 40)
Query Neighborhood Hits	200	Target Neighborhood Hits	1041	Shared Neighborhood Hits	75
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

ORC1_HUMAN
θ value	5.27518 (rank : 120)	NC score	0.019528 (rank : 110)
Query Neighborhood Hits	200	Target Neighborhood Hits	102	Shared Neighborhood Hits	16
SwissProt Accessions	Q13415, Q13471, Q5T0F5	Gene names	ORC1L, ORC1, PARC1
Domain Architecture
Description	Origin recognition complex subunit 1 (Replication control protein 1).

RIF1_HUMAN
θ value	5.27518 (rank : 121)	NC score	0.028311 (rank : 69)
Query Neighborhood Hits	200	Target Neighborhood Hits	320	Shared Neighborhood Hits	38
SwissProt Accessions	Q5UIP0, Q5H9R3, Q5UIP2, Q66YK6, Q6PRU2, Q8TE94, Q99772, Q9H830, Q9H9B9, Q9NVP5, Q9Y4R4	Gene names	RIF1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog).

THOC2_HUMAN
θ value	5.27518 (rank : 122)	NC score	0.032596 (rank : 58)
Query Neighborhood Hits	200	Target Neighborhood Hits	337	Shared Neighborhood Hits	32
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

TLN2_HUMAN
θ value	5.27518 (rank : 123)	NC score	0.015184 (rank : 137)
Query Neighborhood Hits	200	Target Neighborhood Hits	157	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y4G6	Gene names	TLN2, KIAA0320
Domain Architecture
Description	Talin-2.

TLN2_MOUSE
θ value	5.27518 (rank : 124)	NC score	0.015070 (rank : 141)
Query Neighborhood Hits	200	Target Neighborhood Hits	149	Shared Neighborhood Hits	8
SwissProt Accessions	Q71LX4, Q8BWK0	Gene names	Tln2
Domain Architecture	No domain graphic available
Description	Talin-2.

TNAP2_MOUSE
θ value	5.27518 (rank : 125)	NC score	0.015096 (rank : 139)
Query Neighborhood Hits	200	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q61333, Q922G1	Gene names	Tnfaip2
Domain Architecture
Description	Tumor necrosis factor, alpha-induced protein 2 (Primary response gene B94 protein).

UBXD8_MOUSE
θ value	5.27518 (rank : 126)	NC score	0.020431 (rank : 107)
Query Neighborhood Hits	200	Target Neighborhood Hits	133	Shared Neighborhood Hits	7
SwissProt Accessions	Q3TDN2, Q3U9W2, Q80TP7, Q80W42	Gene names	Ubxd8, Kiaa0887
Domain Architecture	No domain graphic available
Description	UBX domain-containing protein 8.

VCXC_HUMAN
θ value	5.27518 (rank : 127)	NC score	0.036621 (rank : 44)
Query Neighborhood Hits	200	Target Neighborhood Hits	139	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H321	Gene names	VCXC
Domain Architecture	No domain graphic available
Description	VCX-C protein (Variably charged protein X-C).

ZN318_MOUSE
θ value	5.27518 (rank : 128)	NC score	0.021147 (rank : 103)
Query Neighborhood Hits	200	Target Neighborhood Hits	642	Shared Neighborhood Hits	39
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

ZN334_HUMAN
θ value	5.27518 (rank : 129)	NC score	-0.001563 (rank : 200)
Query Neighborhood Hits	200	Target Neighborhood Hits	778	Shared Neighborhood Hits	9
SwissProt Accessions	Q9HCZ1, Q5T6U2, Q9NVW4	Gene names	ZNF334
Domain Architecture
Description	Zinc finger protein 334.

AFF1_MOUSE
θ value	6.88961 (rank : 130)	NC score	0.033692 (rank : 54)
Query Neighborhood Hits	200	Target Neighborhood Hits	351	Shared Neighborhood Hits	27
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

AIM1_HUMAN
θ value	6.88961 (rank : 131)	NC score	0.012868 (rank : 155)
Query Neighborhood Hits	200	Target Neighborhood Hits	247	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y4K1, O00296, Q5VWJ2	Gene names	AIM1
Domain Architecture
Description	Absent in melanoma 1 protein.

AKA12_HUMAN
θ value	6.88961 (rank : 132)	NC score	0.030828 (rank : 63)
Query Neighborhood Hits	200	Target Neighborhood Hits	825	Shared Neighborhood Hits	51
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

AP1M2_HUMAN
θ value	6.88961 (rank : 133)	NC score	0.010010 (rank : 169)
Query Neighborhood Hits	200	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y6Q5, Q9BSI8	Gene names	AP1M2
Domain Architecture
Description	AP-1 complex subunit mu-2 (Adaptor-related protein complex 1 mu-2 subunit) (Mu-adaptin 2) (Adaptor protein complex AP-1 mu-2 subunit) (Golgi adaptor HA1/AP1 adaptin mu-2 subunit) (Clathrin assembly protein assembly protein complex 1 medium chain 2) (AP-mu chain family member mu1B).

AP1M2_MOUSE
θ value	6.88961 (rank : 134)	NC score	0.009934 (rank : 170)
Query Neighborhood Hits	200	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WVP1, Q99LA4, Q9CWP7	Gene names	Ap1m2
Domain Architecture
Description	AP-1 complex subunit mu-2 (Adaptor-related protein complex 1 mu-2 subunit) (Mu-adaptin 2) (Adaptor protein complex AP-1 mu-2 subunit) (Golgi adaptor HA1/AP1 adaptin mu-2 subunit) (Clathrin assembly protein assembly protein complex 1 medium chain 2) (AP-mu chain family member mu1B).

BPTF_HUMAN
θ value	6.88961 (rank : 135)	NC score	0.023584 (rank : 90)
Query Neighborhood Hits	200	Target Neighborhood Hits	786	Shared Neighborhood Hits	51
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

CASP8_MOUSE
θ value	6.88961 (rank : 136)	NC score	0.008095 (rank : 175)
Query Neighborhood Hits	200	Target Neighborhood Hits	57	Shared Neighborhood Hits	3
SwissProt Accessions	O89110, O35669	Gene names	Casp8
Domain Architecture
Description	Caspase-8 precursor (EC 3.4.22.-) (CASP-8) [Contains: Caspase-8 subunit p18; Caspase-8 subunit p10].

CN145_MOUSE
θ value	6.88961 (rank : 137)	NC score	0.013361 (rank : 154)
Query Neighborhood Hits	200	Target Neighborhood Hits	916	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

DC1L2_HUMAN
θ value	6.88961 (rank : 138)	NC score	0.010467 (rank : 167)
Query Neighborhood Hits	200	Target Neighborhood Hits	39	Shared Neighborhood Hits	3
SwissProt Accessions	O43237, Q8TAT3	Gene names	DYNC1LI2, DNCLI2, LIC2
Domain Architecture
Description	Cytoplasmic dynein 1 light intermediate chain 2 (Dynein light intermediate chain 2, cytosolic) (LIC53/55) (LIC-2).

DNMT1_HUMAN
θ value	6.88961 (rank : 139)	NC score	0.042681 (rank : 29)
Query Neighborhood Hits	200	Target Neighborhood Hits	401	Shared Neighborhood Hits	32
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

FR1OP_HUMAN
θ value	6.88961 (rank : 140)	NC score	0.016006 (rank : 134)
Query Neighborhood Hits	200	Target Neighborhood Hits	14	Shared Neighborhood Hits	5
SwissProt Accessions	O95684, Q49AI0, Q5R3F6, Q96EW1	Gene names	FGFR1OP, FOP
Domain Architecture	No domain graphic available
Description	FGFR1 oncogene partner.

GPTC8_HUMAN
θ value	6.88961 (rank : 141)	NC score	0.040717 (rank : 33)
Query Neighborhood Hits	200	Target Neighborhood Hits	366	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

GRLF1_HUMAN
θ value	6.88961 (rank : 142)	NC score	0.009260 (rank : 172)
Query Neighborhood Hits	200	Target Neighborhood Hits	167	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

ITA3_MOUSE
θ value	6.88961 (rank : 143)	NC score	0.005252 (rank : 191)
Query Neighborhood Hits	200	Target Neighborhood Hits	54	Shared Neighborhood Hits	3
SwissProt Accessions	Q62470, Q08441, Q08442	Gene names	Itga3
Domain Architecture
Description	Integrin alpha-3 precursor (Galactoprotein B3) (GAPB3) (VLA-3 alpha chain) (CD49c antigen) [Contains: Integrin alpha-3 heavy chain; Integrin alpha-3 light chain].

KIF1B_MOUSE
θ value	6.88961 (rank : 144)	NC score	0.007137 (rank : 184)
Query Neighborhood Hits	200	Target Neighborhood Hits	167	Shared Neighborhood Hits	4
SwissProt Accessions	Q60575, Q9R0B4, Q9WVE5, Q9Z119	Gene names	Kif1b
Domain Architecture
Description	Kinesin-like protein KIF1B.

M4K4_MOUSE
θ value	6.88961 (rank : 145)	NC score	0.001790 (rank : 196)
Query Neighborhood Hits	200	Target Neighborhood Hits	1560	Shared Neighborhood Hits	34
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

MAT1_MOUSE
θ value	6.88961 (rank : 146)	NC score	0.020433 (rank : 106)
Query Neighborhood Hits	200	Target Neighborhood Hits	217	Shared Neighborhood Hits	10
SwissProt Accessions	P51949, Q3TZP0, Q9D8A0, Q9D8D2	Gene names	Mnat1, Mat1
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35).

MLH3_HUMAN
θ value	6.88961 (rank : 147)	NC score	0.014739 (rank : 143)
Query Neighborhood Hits	200	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UHC1, P49751, Q56DK9, Q9P292, Q9UHC0	Gene names	MLH3
Domain Architecture
Description	DNA mismatch repair protein Mlh3 (MutL protein homolog 3).

NFAT5_MOUSE
θ value	6.88961 (rank : 148)	NC score	0.009462 (rank : 171)
Query Neighborhood Hits	200	Target Neighborhood Hits	162	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WV30	Gene names	Nfat5
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T cell transcription factor NFAT5) (NF-AT5) (Rel domain-containing transcription factor NFAT5).

NOC3L_HUMAN
θ value	6.88961 (rank : 149)	NC score	0.031012 (rank : 62)
Query Neighborhood Hits	200	Target Neighborhood Hits	135	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WTT2, Q9H5M6, Q9H9D8	Gene names	NOC3L, AD24, C10orf117, FAD24
Domain Architecture	No domain graphic available
Description	Nucleolar complex protein 3 homolog (NOC3 protein homolog) (NOC3-like protein) (Nucleolar complex-associated protein 3-like protein) (Factor for adipocyte differentiation 24).

NOC3L_MOUSE
θ value	6.88961 (rank : 150)	NC score	0.027486 (rank : 71)
Query Neighborhood Hits	200	Target Neighborhood Hits	177	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VI84, Q9JKM3	Gene names	Noc3l, Ad24, Fad24
Domain Architecture	No domain graphic available
Description	Nucleolar complex protein 3 homolog (NOC3 protein homolog) (NOC3-like protein) (Nucleolar complex-associated protein 3-like protein) (Factor for adipocyte differentiation 24).

NR2E3_HUMAN
θ value	6.88961 (rank : 151)	NC score	0.002662 (rank : 195)
Query Neighborhood Hits	200	Target Neighborhood Hits	102	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5X4, Q9UHM4	Gene names	NR2E3, PNR, RNR
Domain Architecture
Description	Photoreceptor-specific nuclear receptor (Retina-specific nuclear receptor).

NU153_HUMAN
θ value	6.88961 (rank : 152)	NC score	0.049149 (rank : 20)
Query Neighborhood Hits	200	Target Neighborhood Hits	227	Shared Neighborhood Hits	16
SwissProt Accessions	P49790	Gene names	NUP153
Domain Architecture
Description	Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin).

OXR1_MOUSE
θ value	6.88961 (rank : 153)	NC score	0.027070 (rank : 72)
Query Neighborhood Hits	200	Target Neighborhood Hits	516	Shared Neighborhood Hits	54
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

RAF1_HUMAN
θ value	6.88961 (rank : 154)	NC score	-0.001574 (rank : 201)
Query Neighborhood Hits	200	Target Neighborhood Hits	886	Shared Neighborhood Hits	5
SwissProt Accessions	P04049	Gene names	RAF1, RAF
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

RHG06_HUMAN
θ value	6.88961 (rank : 155)	NC score	0.010382 (rank : 168)
Query Neighborhood Hits	200	Target Neighborhood Hits	114	Shared Neighborhood Hits	12
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

SETBP_HUMAN
θ value	6.88961 (rank : 156)	NC score	0.016497 (rank : 129)
Query Neighborhood Hits	200	Target Neighborhood Hits	305	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y6X0, Q9UEF3	Gene names	SETBP1, KIAA0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

SGOL2_HUMAN
θ value	6.88961 (rank : 157)	NC score	0.020804 (rank : 104)
Query Neighborhood Hits	200	Target Neighborhood Hits	207	Shared Neighborhood Hits	17
SwissProt Accessions	Q562F6, Q53RR9, Q53T20, Q86XY4, Q8IWK2, Q8IZK1, Q8N1Q5, Q96LQ3	Gene names	SGOL2
Domain Architecture	No domain graphic available
Description	Shugoshin-like 2 (Tripin).

SMG1_MOUSE
θ value	6.88961 (rank : 158)	NC score	0.014095 (rank : 148)
Query Neighborhood Hits	200	Target Neighborhood Hits	212	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BKX6, Q5DU42, Q6ZQC0, Q8BLU4, Q8BWJ5, Q8BXD3	Gene names	Smg1, Kiaa0421
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1).

SOX2_HUMAN
θ value	6.88961 (rank : 159)	NC score	0.006900 (rank : 187)
Query Neighborhood Hits	200	Target Neighborhood Hits	89	Shared Neighborhood Hits	5
SwissProt Accessions	P48431, Q14537	Gene names	SOX2
Domain Architecture
Description	Transcription factor SOX-2.

SOX2_MOUSE
θ value	6.88961 (rank : 160)	NC score	0.007005 (rank : 185)
Query Neighborhood Hits	200	Target Neighborhood Hits	90	Shared Neighborhood Hits	5
SwissProt Accessions	P48432	Gene names	Sox2, Sox-2
Domain Architecture
Description	Transcription factor SOX-2.

UBP43_MOUSE
θ value	6.88961 (rank : 161)	NC score	0.006872 (rank : 188)
Query Neighborhood Hits	200	Target Neighborhood Hits	130	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BUM9, Q8VDP5	Gene names	Usp43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

UBXD8_HUMAN
θ value	6.88961 (rank : 162)	NC score	0.019165 (rank : 113)
Query Neighborhood Hits	200	Target Neighborhood Hits	131	Shared Neighborhood Hits	7
SwissProt Accessions	Q96CS3, O94963, Q8IUF2, Q9BRP2, Q9BVM7	Gene names	UBXD8, ETEA, KIAA0887
Domain Architecture	No domain graphic available
Description	UBX domain-containing protein 8 (Protein ETEA).

WDR60_MOUSE
θ value	6.88961 (rank : 163)	NC score	0.021192 (rank : 102)
Query Neighborhood Hits	200	Target Neighborhood Hits	344	Shared Neighborhood Hits	29
SwissProt Accessions	Q8C761, Q3UNM4	Gene names	Wdr60
Domain Architecture	No domain graphic available
Description	WD repeat protein 60.

ZBTB5_HUMAN
θ value	6.88961 (rank : 164)	NC score	0.000426 (rank : 199)
Query Neighborhood Hits	200	Target Neighborhood Hits	811	Shared Neighborhood Hits	10
SwissProt Accessions	O15062	Gene names	ZBTB5, KIAA0354
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 5.

ZFP95_HUMAN
θ value	6.88961 (rank : 165)	NC score	-0.001638 (rank : 202)
Query Neighborhood Hits	200	Target Neighborhood Hits	775	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y2L8	Gene names	ZFP95, KIAA1015
Domain Architecture
Description	Zinc finger protein 95 homolog (Zfp-95).

ADNP_MOUSE
θ value	8.99809 (rank : 166)	NC score	0.025731 (rank : 78)
Query Neighborhood Hits	200	Target Neighborhood Hits	232	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Z103	Gene names	Adnp
Domain Architecture
Description	Activity-dependent neuroprotector (Activity-dependent neuroprotective protein).

AZI1_MOUSE
θ value	8.99809 (rank : 167)	NC score	0.011567 (rank : 163)
Query Neighborhood Hits	200	Target Neighborhood Hits	990	Shared Neighborhood Hits	30
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

BRCA2_MOUSE
θ value	8.99809 (rank : 168)	NC score	0.012500 (rank : 159)
Query Neighborhood Hits	200	Target Neighborhood Hits	222	Shared Neighborhood Hits	18
SwissProt Accessions	P97929, O35922, P97383	Gene names	Brca2, Fancd1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein homolog (Fanconi anemia group D1 protein homolog).

BSN_MOUSE
θ value	8.99809 (rank : 169)	NC score	0.034200 (rank : 52)
Query Neighborhood Hits	200	Target Neighborhood Hits	2057	Shared Neighborhood Hits	62
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CAC1B_MOUSE
θ value	8.99809 (rank : 170)	NC score	0.008207 (rank : 174)
Query Neighborhood Hits	200	Target Neighborhood Hits	351	Shared Neighborhood Hits	12
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CHIT1_MOUSE
θ value	8.99809 (rank : 171)	NC score	0.005548 (rank : 190)
Query Neighborhood Hits	200	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D7Q1, Q6QJD2	Gene names	Chit1
Domain Architecture
Description	Chitotriosidase-1 precursor (EC 3.2.1.14) (Chitinase-1).

CMTA1_HUMAN
θ value	8.99809 (rank : 172)	NC score	0.013466 (rank : 153)
Query Neighborhood Hits	200	Target Neighborhood Hits	217	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

CRIM1_HUMAN
θ value	8.99809 (rank : 173)	NC score	0.003656 (rank : 193)
Query Neighborhood Hits	200	Target Neighborhood Hits	362	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

CS1A_MOUSE
θ value	8.99809 (rank : 174)	NC score	0.001654 (rank : 197)
Query Neighborhood Hits	200	Target Neighborhood Hits	360	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

CS1B_MOUSE
θ value	8.99809 (rank : 175)	NC score	0.001578 (rank : 198)
Query Neighborhood Hits	200	Target Neighborhood Hits	361	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

CTND2_HUMAN
θ value	8.99809 (rank : 176)	NC score	0.007863 (rank : 178)
Query Neighborhood Hits	200	Target Neighborhood Hits	333	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

DSPP_MOUSE
θ value	8.99809 (rank : 177)	NC score	0.059686 (rank : 15)
Query Neighborhood Hits	200	Target Neighborhood Hits	491	Shared Neighborhood Hits	41
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

E41LA_MOUSE
θ value	8.99809 (rank : 178)	NC score	0.014164 (rank : 147)
Query Neighborhood Hits	200	Target Neighborhood Hits	85	Shared Neighborhood Hits	16
SwissProt Accessions	P52963	Gene names	Epb41l4a, Epb4.1l4, Epb4.1l4a, Epb41l4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

FILA_HUMAN
θ value	8.99809 (rank : 179)	NC score	0.026945 (rank : 74)
Query Neighborhood Hits	200	Target Neighborhood Hits	685	Shared Neighborhood Hits	36
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

GGA3_MOUSE
θ value	8.99809 (rank : 180)	NC score	0.007275 (rank : 182)
Query Neighborhood Hits	200	Target Neighborhood Hits	148	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BMI3, Q80U71	Gene names	Gga3, Kiaa0154
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

JUND_MOUSE
θ value	8.99809 (rank : 181)	NC score	0.007262 (rank : 183)
Query Neighborhood Hits	200	Target Neighborhood Hits	134	Shared Neighborhood Hits	4
SwissProt Accessions	P15066	Gene names	Jund, Jun-d, Jund1
Domain Architecture
Description	Transcription factor jun-D.

KCTD2_HUMAN
θ value	8.99809 (rank : 182)	NC score	0.012766 (rank : 157)
Query Neighborhood Hits	200	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	Q14681	Gene names	KCTD2, KIAA0176
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD2.

MYH8_MOUSE
θ value	8.99809 (rank : 183)	NC score	0.011797 (rank : 162)
Query Neighborhood Hits	200	Target Neighborhood Hits	1600	Shared Neighborhood Hits	53
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

NCOA6_HUMAN
θ value	8.99809 (rank : 184)	NC score	0.016219 (rank : 133)
Query Neighborhood Hits	200	Target Neighborhood Hits	1202	Shared Neighborhood Hits	40
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

PDPK1_MOUSE
θ value	8.99809 (rank : 185)	NC score	-0.002406 (rank : 203)
Query Neighborhood Hits	200	Target Neighborhood Hits	852	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z2A0, Q9R1D8, Q9R215	Gene names	Pdpk1, Pdk1
Domain Architecture
Description	3-phosphoinositide-dependent protein kinase 1 (EC 2.7.11.1) (mPDK1).

PER2_HUMAN
θ value	8.99809 (rank : 186)	NC score	0.007432 (rank : 181)
Query Neighborhood Hits	200	Target Neighborhood Hits	170	Shared Neighborhood Hits	9
SwissProt Accessions	O15055	Gene names	PER2, KIAA0347
Domain Architecture
Description	Period circadian protein 2.

PKP1_HUMAN
θ value	8.99809 (rank : 187)	NC score	0.007925 (rank : 177)
Query Neighborhood Hits	200	Target Neighborhood Hits	36	Shared Neighborhood Hits	5
SwissProt Accessions	Q13835, O00645, Q15152	Gene names	PKP1
Domain Architecture
Description	Plakophilin-1 (Band-6 protein) (B6P).

RM03_HUMAN
θ value	8.99809 (rank : 188)	NC score	0.019874 (rank : 109)
Query Neighborhood Hits	200	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	P09001	Gene names	MRPL3, MRL3
Domain Architecture
Description	Mitochondrial 39S ribosomal protein L3 (L3mt) (MRP-L3).

RNF34_MOUSE
θ value	8.99809 (rank : 189)	NC score	0.008055 (rank : 176)
Query Neighborhood Hits	200	Target Neighborhood Hits	160	Shared Neighborhood Hits	6
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

RWDD1_HUMAN
θ value	8.99809 (rank : 190)	NC score	0.016853 (rank : 125)
Query Neighborhood Hits	200	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H446, Q9Y313, Q9Y6B3	Gene names	RWDD1
Domain Architecture
Description	RWD domain-containing protein 1.

RWDD1_MOUSE
θ value	8.99809 (rank : 191)	NC score	0.016618 (rank : 128)
Query Neighborhood Hits	200	Target Neighborhood Hits	33	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CQK7	Gene names	Rwdd1
Domain Architecture
Description	RWD domain-containing protein 1 (IH1).

SGOL2_MOUSE
θ value	8.99809 (rank : 192)	NC score	0.017964 (rank : 120)
Query Neighborhood Hits	200	Target Neighborhood Hits	112	Shared Neighborhood Hits	11
SwissProt Accessions	Q7TSY8, Q811I4, Q8C9C4, Q8CGJ4, Q9CS55	Gene names	Sgol2
Domain Architecture	No domain graphic available
Description	Shugoshin-like 2.

SRBS1_MOUSE
θ value	8.99809 (rank : 193)	NC score	0.013834 (rank : 152)
Query Neighborhood Hits	200	Target Neighborhood Hits	409	Shared Neighborhood Hits	17
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

TCLB2_MOUSE
θ value	8.99809 (rank : 194)	NC score	0.020127 (rank : 108)
Query Neighborhood Hits	200	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	P56841	Gene names	Tcl1b2
Domain Architecture
Description	TCL1B2 protein.

UACA_HUMAN
θ value	8.99809 (rank : 195)	NC score	0.012504 (rank : 158)
Query Neighborhood Hits	200	Target Neighborhood Hits	1622	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

VP13A_HUMAN
θ value	8.99809 (rank : 196)	NC score	0.018750 (rank : 115)
Query Neighborhood Hits	200	Target Neighborhood Hits	93	Shared Neighborhood Hits	7
SwissProt Accessions	Q96RL7, Q5JSX9, Q5JSY0, Q5VYR5, Q702P4, Q709D0, Q86YF8, Q96S61, Q9H995, Q9Y2J1	Gene names	VPS13A, CHAC, KIAA0986
Domain Architecture
Description	Vacuolar protein sorting-associated protein 13A (Chorein) (Chorea- acanthocytosis protein).

YAP1_HUMAN
θ value	8.99809 (rank : 197)	NC score	0.009179 (rank : 173)
Query Neighborhood Hits	200	Target Neighborhood Hits	173	Shared Neighborhood Hits	9
SwissProt Accessions	P46937	Gene names	YAP1, YAP65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

ZC313_HUMAN
θ value	8.99809 (rank : 198)	NC score	0.023921 (rank : 88)
Query Neighborhood Hits	200	Target Neighborhood Hits	772	Shared Neighborhood Hits	46
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

ZN207_HUMAN
θ value	8.99809 (rank : 199)	NC score	0.025589 (rank : 81)
Query Neighborhood Hits	200	Target Neighborhood Hits	326	Shared Neighborhood Hits	10
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

ZN638_MOUSE
θ value	8.99809 (rank : 200)	NC score	0.022697 (rank : 97)
Query Neighborhood Hits	200	Target Neighborhood Hits	318	Shared Neighborhood Hits	26
SwissProt Accessions	Q61464, Q6DFV9, Q8C941	Gene names	Znf638, Np220, Zfml
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein).

CASG_MOUSE
θ value	θ > 10 (rank : 201)	NC score	0.057852 (rank : 17)
Query Neighborhood Hits	200	Target Neighborhood Hits	9	Shared Neighborhood Hits	1
SwissProt Accessions	Q02862	Gene names	Csng
Domain Architecture	No domain graphic available
Description	Gamma-casein precursor (PP22).

DPOE1_HUMAN
θ value	θ > 10 (rank : 202)	NC score	0.064322 (rank : 12)
Query Neighborhood Hits	200	Target Neighborhood Hits	42	Shared Neighborhood Hits	7
SwissProt Accessions	Q07864, Q13533, Q86VH9	Gene names	POLE, POLE1
Domain Architecture
Description	DNA polymerase epsilon, catalytic subunit A (EC 2.7.7.7) (DNA polymerase II subunit A).

DPOE1_MOUSE
θ value	θ > 10 (rank : 203)	NC score	0.064109 (rank : 13)
Query Neighborhood Hits	200	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WVF7, Q9QX50	Gene names	Pole, Pole1
Domain Architecture
Description	DNA polymerase epsilon, catalytic subunit A (EC 2.7.7.7) (DNA polymerase II subunit A).

Hits sorted by NC score

DPOLZ_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	200	Target Neighborhood Hits	200	Shared Neighborhood Hits	200
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

DPOLZ_MOUSE
NC score	0.967263 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	200	Target Neighborhood Hits	169	Shared Neighborhood Hits	43
SwissProt Accessions	Q61493, Q9JMD6, Q9QWX6	Gene names	Rev3l, Polz, Sez4
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (Seizure-related protein 4).

DPOD1_MOUSE
NC score	0.804768 (rank : 3)	θ value	2.64101e-84 (rank : 3)
Query Neighborhood Hits	200	Target Neighborhood Hits	19	Shared Neighborhood Hits	6
SwissProt Accessions	P52431, O54883	Gene names	Pold1
Domain Architecture
Description	DNA polymerase delta catalytic subunit (EC 2.7.7.7).

DPOD1_HUMAN
NC score	0.803381 (rank : 4)	θ value	1.71185e-83 (rank : 4)
Query Neighborhood Hits	200	Target Neighborhood Hits	28	Shared Neighborhood Hits	6
SwissProt Accessions	P28340, Q8NER3, Q96H98	Gene names	POLD1, POLD
Domain Architecture
Description	DNA polymerase delta catalytic subunit (EC 2.7.7.7) (DNA polymerase subunit delta p125).

DPOLA_HUMAN
NC score	0.638448 (rank : 5)	θ value	2.12192e-33 (rank : 6)
Query Neighborhood Hits	200	Target Neighborhood Hits	41	Shared Neighborhood Hits	6
SwissProt Accessions	P09884, Q86UQ7	Gene names	POLA1, POLA
Domain Architecture
Description	DNA polymerase alpha catalytic subunit (EC 2.7.7.7).

DPOLA_MOUSE
NC score	0.638419 (rank : 6)	θ value	1.46948e-34 (rank : 5)
Query Neighborhood Hits	200	Target Neighborhood Hits	56	Shared Neighborhood Hits	10
SwissProt Accessions	P33609	Gene names	Pola1, Pola
Domain Architecture
Description	DNA polymerase alpha catalytic subunit (EC 2.7.7.7).

SGP50_MOUSE
NC score	0.136928 (rank : 7)	θ value	0.00869519 (rank : 8)
Query Neighborhood Hits	200	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q02596	Gene names	Glycam1
Domain Architecture
Description	Sulfated 50 kDa glycoprotein precursor (SGP50) (Endothelial ligand FOR L-selectin) (Glycosylation-dependent cell adhesion molecule 1) (GlyCAM-1) (MC26).

LYRIC_HUMAN
NC score	0.083891 (rank : 8)	θ value	0.0431538 (rank : 12)
Query Neighborhood Hits	200	Target Neighborhood Hits	99	Shared Neighborhood Hits	16
SwissProt Accessions	Q86UE4, Q6PK07, Q8TCX3	Gene names	MTDH, AEG1, LYRIC
Domain Architecture	No domain graphic available
Description	Protein LYRIC (Lysine-rich CEACAM1 co-isolated protein) (3D3/lyric) (Metastasis adhesion protein) (Metadherin) (Astrocyte elevated gene-1 protein) (AEG-1).

LYRIC_MOUSE
NC score	0.082754 (rank : 9)	θ value	0.0563607 (rank : 15)
Query Neighborhood Hits	200	Target Neighborhood Hits	126	Shared Neighborhood Hits	14
SwissProt Accessions	Q80WJ7, Q3U9F8, Q3UAQ8, Q8BN67, Q8CBT9, Q8CDL0, Q8CGI7, Q9D052	Gene names	Mtdh, Lyric
Domain Architecture	No domain graphic available
Description	Protein LYRIC (Lysine-rich CEACAM1 co-isolated protein) (3D3/LYRIC) (Metastasis adhesion protein) (Metadherin).

DSPP_HUMAN
NC score	0.081797 (rank : 10)	θ value	0.0193708 (rank : 10)
Query Neighborhood Hits	200	Target Neighborhood Hits	645	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

SEMG2_HUMAN
NC score	0.081609 (rank : 11)	θ value	0.00134147 (rank : 7)
Query Neighborhood Hits	200	Target Neighborhood Hits	251	Shared Neighborhood Hits	31
SwissProt Accessions	Q02383, Q6X2M6	Gene names	SEMG2
Domain Architecture
Description	Semenogelin-2 precursor (Semenogelin II) (SGII).

DPOE1_HUMAN
NC score	0.064322 (rank : 12)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	200	Target Neighborhood Hits	42	Shared Neighborhood Hits	7
SwissProt Accessions	Q07864, Q13533, Q86VH9	Gene names	POLE, POLE1
Domain Architecture
Description	DNA polymerase epsilon, catalytic subunit A (EC 2.7.7.7) (DNA polymerase II subunit A).

DPOE1_MOUSE
NC score	0.064109 (rank : 13)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	200	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WVF7, Q9QX50	Gene names	Pole, Pole1
Domain Architecture
Description	DNA polymerase epsilon, catalytic subunit A (EC 2.7.7.7) (DNA polymerase II subunit A).

RSF1_HUMAN
NC score	0.061996 (rank : 14)	θ value	0.0563607 (rank : 16)
Query Neighborhood Hits	200	Target Neighborhood Hits	539	Shared Neighborhood Hits	46
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

DSPP_MOUSE
NC score	0.059686 (rank : 15)	θ value	8.99809 (rank : 177)
Query Neighborhood Hits	200	Target Neighborhood Hits	491	Shared Neighborhood Hits	41
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

UBP1_HUMAN
NC score	0.058598 (rank : 16)	θ value	0.365318 (rank : 25)
Query Neighborhood Hits	200	Target Neighborhood Hits	259	Shared Neighborhood Hits	20
SwissProt Accessions	O94782, Q9UFR0, Q9UNJ3	Gene names	USP1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.1.2.15) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) (Deubiquitinating enzyme 1) (hUBP).

CASG_MOUSE
NC score	0.057852 (rank : 17)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	200	Target Neighborhood Hits	9	Shared Neighborhood Hits	1
SwissProt Accessions	Q02862	Gene names	Csng
Domain Architecture	No domain graphic available
Description	Gamma-casein precursor (PP22).

PCLO_HUMAN
NC score	0.053434 (rank : 18)	θ value	0.0252991 (rank : 11)
Query Neighborhood Hits	200	Target Neighborhood Hits	2046	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

EMSY_HUMAN
NC score	0.052244 (rank : 19)	θ value	0.0736092 (rank : 17)
Query Neighborhood Hits	200	Target Neighborhood Hits	296	Shared Neighborhood Hits	16
SwissProt Accessions	Q7Z589, Q4G109, Q8NBU6, Q8TE50, Q9H8I9, Q9NRH0	Gene names	EMSY, C11orf30
Domain Architecture
Description	Protein EMSY.

NU153_HUMAN
NC score	0.049149 (rank : 20)	θ value	6.88961 (rank : 152)
Query Neighborhood Hits	200	Target Neighborhood Hits	227	Shared Neighborhood Hits	16
SwissProt Accessions	P49790	Gene names	NUP153
Domain Architecture
Description	Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin).

RBBP6_MOUSE
NC score	0.048906 (rank : 21)	θ value	4.03905 (rank : 99)
Query Neighborhood Hits	200	Target Neighborhood Hits	1014	Shared Neighborhood Hits	67
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

MYCB2_HUMAN
NC score	0.048561 (rank : 22)	θ value	0.0113563 (rank : 9)
Query Neighborhood Hits	200	Target Neighborhood Hits	390	Shared Neighborhood Hits	22
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

RBBP6_HUMAN
NC score	0.047706 (rank : 23)	θ value	2.36792 (rank : 62)
Query Neighborhood Hits	200	Target Neighborhood Hits	1135	Shared Neighborhood Hits	66
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

ADNP_HUMAN
NC score	0.047192 (rank : 24)	θ value	0.47712 (rank : 26)
Query Neighborhood Hits	200	Target Neighborhood Hits	265	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H2P0, O94881, Q9UG34	Gene names	ADNP, KIAA0784
Domain Architecture
Description	Activity-dependent neuroprotector (Activity-dependent neuroprotective protein).

UBP2L_MOUSE
NC score	0.046896 (rank : 25)	θ value	2.36792 (rank : 70)
Query Neighborhood Hits	200	Target Neighborhood Hits	173	Shared Neighborhood Hits	21
SwissProt Accessions	Q80X50, Q8BIT6, Q8BIW4, Q8BJ01, Q8CIG7, Q8K102, Q9CRT6	Gene names	Ubap2l
Domain Architecture	No domain graphic available
Description	Ubiquitin-associated protein 2-like.

UBP2L_HUMAN
NC score	0.046856 (rank : 26)	θ value	1.38821 (rank : 46)
Query Neighborhood Hits	200	Target Neighborhood Hits	170	Shared Neighborhood Hits	18
SwissProt Accessions	Q14157, Q5VU75, Q5VU76, Q9BTU3, Q9UGL5	Gene names	UBAP2L, KIAA0144, NICE4
Domain Architecture
Description	Ubiquitin-associated protein 2-like (Protein NICE-4).

RRP5_HUMAN
NC score	0.043630 (rank : 27)	θ value	1.81305 (rank : 56)
Query Neighborhood Hits	200	Target Neighborhood Hits	291	Shared Neighborhood Hits	29
SwissProt Accessions	Q14690, Q86VQ8	Gene names	PDCD11, KIAA0185
Domain Architecture
Description	RRP5 protein homolog (Programmed cell death protein 11).

PCLO_MOUSE
NC score	0.043324 (rank : 28)	θ value	0.0431538 (rank : 13)
Query Neighborhood Hits	200	Target Neighborhood Hits	2275	Shared Neighborhood Hits	70
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

DNMT1_HUMAN
NC score	0.042681 (rank : 29)	θ value	6.88961 (rank : 139)
Query Neighborhood Hits	200	Target Neighborhood Hits	401	Shared Neighborhood Hits	32
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

TP53B_MOUSE
NC score	0.042670 (rank : 30)	θ value	4.03905 (rank : 104)
Query Neighborhood Hits	200	Target Neighborhood Hits	644	Shared Neighborhood Hits	49
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

DMP1_HUMAN
NC score	0.042661 (rank : 31)	θ value	3.0926 (rank : 74)
Query Neighborhood Hits	200	Target Neighborhood Hits	491	Shared Neighborhood Hits	45
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

TGON2_HUMAN
NC score	0.040867 (rank : 32)	θ value	2.36792 (rank : 69)
Query Neighborhood Hits	200	Target Neighborhood Hits	1037	Shared Neighborhood Hits	63
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

GPTC8_HUMAN
NC score	0.040717 (rank : 33)	θ value	6.88961 (rank : 141)
Query Neighborhood Hits	200	Target Neighborhood Hits	366	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

SNX11_MOUSE
NC score	0.040217 (rank : 34)	θ value	1.06291 (rank : 43)
Query Neighborhood Hits	200	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	Q91WL6, Q3V3A6	Gene names	Snx11
Domain Architecture	No domain graphic available
Description	Sorting nexin-11.

PO121_MOUSE
NC score	0.039021 (rank : 35)	θ value	0.279714 (rank : 23)
Query Neighborhood Hits	200	Target Neighborhood Hits	345	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

SENP6_HUMAN
NC score	0.038915 (rank : 36)	θ value	2.36792 (rank : 64)
Query Neighborhood Hits	200	Target Neighborhood Hits	69	Shared Neighborhood Hits	8
SwissProt Accessions	Q9GZR1, O94891, Q8TBY4, Q9UJV5	Gene names	SENP6, KIAA0797, SSP1, SUSP1
Domain Architecture
Description	Sentrin-specific protease 6 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP6) (SUMO-1-specific protease 1).

P80C_HUMAN
NC score	0.038769 (rank : 37)	θ value	4.03905 (rank : 98)
Query Neighborhood Hits	200	Target Neighborhood Hits	73	Shared Neighborhood Hits	8
SwissProt Accessions	P38432	Gene names	COIL, CLN80
Domain Architecture	No domain graphic available
Description	Coilin (p80).

TXND2_MOUSE
NC score	0.038592 (rank : 38)	θ value	4.03905 (rank : 105)
Query Neighborhood Hits	200	Target Neighborhood Hits	828	Shared Neighborhood Hits	62
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

LEO1_HUMAN
NC score	0.038211 (rank : 39)	θ value	1.81305 (rank : 51)
Query Neighborhood Hits	200	Target Neighborhood Hits	958	Shared Neighborhood Hits	58
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

NPBL_MOUSE
NC score	0.037401 (rank : 40)	θ value	5.27518 (rank : 119)
Query Neighborhood Hits	200	Target Neighborhood Hits	1041	Shared Neighborhood Hits	75
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

TRDN_HUMAN
NC score	0.037360 (rank : 41)	θ value	3.0926 (rank : 86)
Query Neighborhood Hits	200	Target Neighborhood Hits	542	Shared Neighborhood Hits	39
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

CEP35_HUMAN
NC score	0.036872 (rank : 42)	θ value	0.47712 (rank : 28)
Query Neighborhood Hits	200	Target Neighborhood Hits	811	Shared Neighborhood Hits	48
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

CCNT2_HUMAN
NC score	0.036845 (rank : 43)	θ value	1.38821 (rank : 44)
Query Neighborhood Hits	200	Target Neighborhood Hits	84	Shared Neighborhood Hits	12
SwissProt Accessions	O60583, O60582, Q5I1Y0	Gene names	CCNT2
Domain Architecture
Description	Cyclin-T2 (CycT2).

VCXC_HUMAN
NC score	0.036621 (rank : 44)	θ value	5.27518 (rank : 127)
Query Neighborhood Hits	200	Target Neighborhood Hits	139	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H321	Gene names	VCXC
Domain Architecture	No domain graphic available
Description	VCX-C protein (Variably charged protein X-C).

EMSY_MOUSE
NC score	0.036506 (rank : 45)	θ value	4.03905 (rank : 90)
Query Neighborhood Hits	200	Target Neighborhood Hits	294	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BMB0, Q5FWK5, Q80XU1, Q8VDW9	Gene names	Emsy
Domain Architecture
Description	Protein EMSY.

FSD1L_MOUSE
NC score	0.036061 (rank : 46)	θ value	1.81305 (rank : 48)
Query Neighborhood Hits	200	Target Neighborhood Hits	78	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BYN5, Q3USW7	Gene names	Fsd1l, Ccdc10, Csdufd1, Fsd1nl
Domain Architecture	No domain graphic available
Description	FSD1-like protein (FSD1 N-terminal-like protein) (Coiled-coil domain- containing protein 10).

MYST4_HUMAN
NC score	0.035987 (rank : 47)	θ value	0.0961366 (rank : 18)
Query Neighborhood Hits	200	Target Neighborhood Hits	671	Shared Neighborhood Hits	48
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

AF9_HUMAN
NC score	0.035517 (rank : 48)	θ value	3.0926 (rank : 72)
Query Neighborhood Hits	200	Target Neighborhood Hits	202	Shared Neighborhood Hits	24
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

ARFG3_HUMAN
NC score	0.035235 (rank : 49)	θ value	0.279714 (rank : 20)
Query Neighborhood Hits	200	Target Neighborhood Hits	56	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NP61, Q9BSC6, Q9H9J0, Q9NT10, Q9NUP5, Q9Y4V3, Q9Y4V4	Gene names	ARFGAP3, ARFGAP1
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

PDLI1_HUMAN
NC score	0.034973 (rank : 50)	θ value	1.81305 (rank : 53)
Query Neighborhood Hits	200	Target Neighborhood Hits	242	Shared Neighborhood Hits	3
SwissProt Accessions	O00151, Q5VZH5, Q9BPZ9	Gene names	PDLIM1, CLIM1, CLP36
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

NKTR_HUMAN
NC score	0.034399 (rank : 51)	θ value	0.163984 (rank : 19)
Query Neighborhood Hits	200	Target Neighborhood Hits	658	Shared Neighborhood Hits	52
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

BSN_MOUSE
NC score	0.034200 (rank : 52)	θ value	8.99809 (rank : 169)
Query Neighborhood Hits	200	Target Neighborhood Hits	2057	Shared Neighborhood Hits	62
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

SFR11_HUMAN
NC score	0.033758 (rank : 53)	θ value	4.03905 (rank : 103)
Query Neighborhood Hits	200	Target Neighborhood Hits	246	Shared Neighborhood Hits	24
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

AFF1_MOUSE
NC score	0.033692 (rank : 54)	θ value	6.88961 (rank : 130)
Query Neighborhood Hits	200	Target Neighborhood Hits	351	Shared Neighborhood Hits	27
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

MATR3_MOUSE
NC score	0.033224 (rank : 55)	θ value	3.0926 (rank : 79)
Query Neighborhood Hits	200	Target Neighborhood Hits	321	Shared Neighborhood Hits	27
SwissProt Accessions	Q8K310	Gene names	Matr3
Domain Architecture	No domain graphic available
Description	Matrin-3.

HRX_HUMAN
NC score	0.032875 (rank : 56)	θ value	3.0926 (rank : 77)
Query Neighborhood Hits	200	Target Neighborhood Hits	825	Shared Neighborhood Hits	41
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

GP179_HUMAN
NC score	0.032848 (rank : 57)	θ value	4.03905 (rank : 93)
Query Neighborhood Hits	200	Target Neighborhood Hits	372	Shared Neighborhood Hits	19
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

THOC2_HUMAN
NC score	0.032596 (rank : 58)	θ value	5.27518 (rank : 122)
Query Neighborhood Hits	200	Target Neighborhood Hits	337	Shared Neighborhood Hits	32
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

GDE_HUMAN
NC score	0.031972 (rank : 59)	θ value	1.81305 (rank : 49)
Query Neighborhood Hits	200	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	P35573, P78354, P78544, Q9UF08	Gene names	AGL, GDE
Domain Architecture
Description	Glycogen debranching enzyme (Glycogen debrancher) [Includes: 4-alpha- glucanotransferase (EC 2.4.1.25) (Oligo-1,4-1,4-glucantransferase); Amylo-alpha-1,6-glucosidase (EC 3.2.1.33) (Amylo-1,6-glucosidase) (Dextrin 6-alpha-D-glucosidase)].

MEPE_HUMAN
NC score	0.031752 (rank : 60)	θ value	5.27518 (rank : 117)
Query Neighborhood Hits	200	Target Neighborhood Hits	105	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NQ76	Gene names	MEPE
Domain Architecture
Description	Matrix extracellular phosphoglycoprotein precursor (Osteoblast/osteocyte factor 45) (OF45).

SRRM2_HUMAN
NC score	0.031057 (rank : 61)	θ value	2.36792 (rank : 68)
Query Neighborhood Hits	200	Target Neighborhood Hits	1296	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

NOC3L_HUMAN
NC score	0.031012 (rank : 62)	θ value	6.88961 (rank : 149)
Query Neighborhood Hits	200	Target Neighborhood Hits	135	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WTT2, Q9H5M6, Q9H9D8	Gene names	NOC3L, AD24, C10orf117, FAD24
Domain Architecture	No domain graphic available
Description	Nucleolar complex protein 3 homolog (NOC3 protein homolog) (NOC3-like protein) (Nucleolar complex-associated protein 3-like protein) (Factor for adipocyte differentiation 24).

AKA12_HUMAN
NC score	0.030828 (rank : 63)	θ value	6.88961 (rank : 132)
Query Neighborhood Hits	200	Target Neighborhood Hits	825	Shared Neighborhood Hits	51
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

EXOC8_MOUSE
NC score	0.030550 (rank : 64)	θ value	1.06291 (rank : 38)
Query Neighborhood Hits	200	Target Neighborhood Hits	43	Shared Neighborhood Hits	5
SwissProt Accessions	Q6PGF7	Gene names	Exoc8
Domain Architecture	No domain graphic available
Description	Exocyst complex component 8 (Exocyst complex 84 kDa subunit).

NUP50_HUMAN
NC score	0.030300 (rank : 65)	θ value	1.81305 (rank : 52)
Query Neighborhood Hits	200	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UKX7, O75644, Q9NPM9, Q9NPR6, Q9P1K5	Gene names	NUP50, NPAP60L
Domain Architecture
Description	Nucleoporin 50 kDa (Nuclear pore-associated protein 60 kDa-like).

FSD1L_HUMAN
NC score	0.029716 (rank : 66)	θ value	4.03905 (rank : 92)
Query Neighborhood Hits	200	Target Neighborhood Hits	57	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BXM9, Q5T880	Gene names	FSD1L, CCDC10, CSDUFD1, FSD1NL
Domain Architecture	No domain graphic available
Description	FSD1-like protein (FSD1 N-terminal-like protein) (Coiled-coil domain- containing protein 10).

MATR3_HUMAN
NC score	0.029682 (rank : 67)	θ value	5.27518 (rank : 116)
Query Neighborhood Hits	200	Target Neighborhood Hits	325	Shared Neighborhood Hits	27
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

OTU6B_MOUSE
NC score	0.028630 (rank : 68)	θ value	0.813845 (rank : 37)
Query Neighborhood Hits	200	Target Neighborhood Hits	202	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K2H2	Gene names	Otud6b
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 6B.

RIF1_HUMAN
NC score	0.028311 (rank : 69)	θ value	5.27518 (rank : 121)
Query Neighborhood Hits	200	Target Neighborhood Hits	320	Shared Neighborhood Hits	38
SwissProt Accessions	Q5UIP0, Q5H9R3, Q5UIP2, Q66YK6, Q6PRU2, Q8TE94, Q99772, Q9H830, Q9H9B9, Q9NVP5, Q9Y4R4	Gene names	RIF1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog).

HAP1_HUMAN
NC score	0.027508 (rank : 70)	θ value	0.62314 (rank : 32)
Query Neighborhood Hits	200	Target Neighborhood Hits	606	Shared Neighborhood Hits	22
SwissProt Accessions	P54257, O75358, Q9H4G3, Q9HA98, Q9NY90	Gene names	HAP1, HLP1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1) (Neuroan 1).

NOC3L_MOUSE
NC score	0.027486 (rank : 71)	θ value	6.88961 (rank : 150)
Query Neighborhood Hits	200	Target Neighborhood Hits	177	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VI84, Q9JKM3	Gene names	Noc3l, Ad24, Fad24
Domain Architecture	No domain graphic available
Description	Nucleolar complex protein 3 homolog (NOC3 protein homolog) (NOC3-like protein) (Nucleolar complex-associated protein 3-like protein) (Factor for adipocyte differentiation 24).

OXR1_MOUSE
NC score	0.027070 (rank : 72)	θ value	6.88961 (rank : 153)
Query Neighborhood Hits	200	Target Neighborhood Hits	516	Shared Neighborhood Hits	54
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

TTC28_HUMAN
NC score	0.027040 (rank : 73)	θ value	0.62314 (rank : 34)
Query Neighborhood Hits	200	Target Neighborhood Hits	271	Shared Neighborhood Hits	17
SwissProt Accessions	Q96AY4, O95928, O95929, Q9NTE4, Q9UG31, Q9UGG5, Q9UPV8, Q9Y3S5	Gene names	TTC28, KIAA1043
Domain Architecture
Description	Tetratricopeptide repeat protein 28 (TPR repeat protein 28).

FILA_HUMAN
NC score	0.026945 (rank : 74)	θ value	8.99809 (rank : 179)
Query Neighborhood Hits	200	Target Neighborhood Hits	685	Shared Neighborhood Hits	36
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

CNOT2_MOUSE
NC score	0.026912 (rank : 75)	θ value	3.0926 (rank : 73)
Query Neighborhood Hits	200	Target Neighborhood Hits	39	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C5L3, Q3UE39, Q80YA5, Q9D0P1	Gene names	Cnot2
Domain Architecture
Description	CCR4-NOT transcription complex subunit 2 (CCR4-associated factor 2).

E41L2_HUMAN
NC score	0.026195 (rank : 76)	θ value	0.0563607 (rank : 14)
Query Neighborhood Hits	200	Target Neighborhood Hits	287	Shared Neighborhood Hits	24
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

PRG4_MOUSE
NC score	0.025856 (rank : 77)	θ value	1.38821 (rank : 45)
Query Neighborhood Hits	200	Target Neighborhood Hits	624	Shared Neighborhood Hits	38
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

ADNP_MOUSE
NC score	0.025731 (rank : 78)	θ value	8.99809 (rank : 166)
Query Neighborhood Hits	200	Target Neighborhood Hits	232	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Z103	Gene names	Adnp
Domain Architecture
Description	Activity-dependent neuroprotector (Activity-dependent neuroprotective protein).

CNOT2_HUMAN
NC score	0.025673 (rank : 79)	θ value	5.27518 (rank : 109)
Query Neighborhood Hits	200	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NZN8, Q9H3E0, Q9NSX5, Q9NWR6, Q9P028	Gene names	CNOT2, CDC36, NOT2
Domain Architecture
Description	CCR4-NOT transcription complex subunit 2 (CCR4-associated factor 2).

CENPE_HUMAN
NC score	0.025593 (rank : 80)	θ value	2.36792 (rank : 58)
Query Neighborhood Hits	200	Target Neighborhood Hits	2060	Shared Neighborhood Hits	73
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

ZN207_HUMAN
NC score	0.025589 (rank : 81)	θ value	8.99809 (rank : 199)
Query Neighborhood Hits	200	Target Neighborhood Hits	326	Shared Neighborhood Hits	10
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

CNOT4_MOUSE
NC score	0.025476 (rank : 82)	θ value	1.81305 (rank : 47)
Query Neighborhood Hits	200	Target Neighborhood Hits	277	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BT14, Q8CCR4, Q9CV74, Q9Z1D0	Gene names	Cnot4, Not4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

RING2_MOUSE
NC score	0.025305 (rank : 83)	θ value	1.81305 (rank : 55)
Query Neighborhood Hits	200	Target Neighborhood Hits	199	Shared Neighborhood Hits	7
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

RING2_HUMAN
NC score	0.025220 (rank : 84)	θ value	1.81305 (rank : 54)
Query Neighborhood Hits	200	Target Neighborhood Hits	201	Shared Neighborhood Hits	7
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

GFPT1_HUMAN
NC score	0.025028 (rank : 85)	θ value	1.81305 (rank : 50)
Query Neighborhood Hits	200	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q06210, Q9BXF8	Gene names	GFPT1, GFAT, GFPT
Domain Architecture
Description	Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1 (EC 2.6.1.16) (Hexosephosphate aminotransferase 1) (D-fructose-6- phosphate amidotransferase 1) (GFAT 1) (GFAT1).

RFC1_MOUSE
NC score	0.024842 (rank : 86)	θ value	2.36792 (rank : 63)
Query Neighborhood Hits	200	Target Neighborhood Hits	290	Shared Neighborhood Hits	24
SwissProt Accessions	P35601	Gene names	Rfc1, Ibf-1, Recc1
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (A1-P145) (Differentiation- specific element-binding protein) (ISRE-binding protein).

GFPT1_MOUSE
NC score	0.024050 (rank : 87)	θ value	2.36792 (rank : 61)
Query Neighborhood Hits	200	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	P47856, Q91XG9, Q99LP7, Q99MJ4	Gene names	Gfpt1, Gfpt
Domain Architecture
Description	Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1 (EC 2.6.1.16) (Hexosephosphate aminotransferase 1) (D-fructose-6- phosphate amidotransferase 1) (GFAT 1) (GFAT1).

ZC313_HUMAN
NC score	0.023921 (rank : 88)	θ value	8.99809 (rank : 198)
Query Neighborhood Hits	200	Target Neighborhood Hits	772	Shared Neighborhood Hits	46
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

CLUA1_MOUSE
NC score	0.023595 (rank : 89)	θ value	4.03905 (rank : 88)
Query Neighborhood Hits	200	Target Neighborhood Hits	261	Shared Neighborhood Hits	14
SwissProt Accessions	Q8R3P7, Q6P3Y8	Gene names	Cluap1
Domain Architecture	No domain graphic available
Description	Clusterin-associated protein 1.

BPTF_HUMAN
NC score	0.023584 (rank : 90)	θ value	6.88961 (rank : 135)
Query Neighborhood Hits	200	Target Neighborhood Hits	786	Shared Neighborhood Hits	51
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

MBD5_HUMAN
NC score	0.023510 (rank : 91)	θ value	4.03905 (rank : 96)
Query Neighborhood Hits	200	Target Neighborhood Hits	176	Shared Neighborhood Hits	13
SwissProt Accessions	Q9P267, Q9NUV6	Gene names	MBD5, KIAA1461
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 5 (Methyl-CpG-binding protein MBD5).

RRBP1_MOUSE
NC score	0.023235 (rank : 92)	θ value	4.03905 (rank : 102)
Query Neighborhood Hits	200	Target Neighborhood Hits	1650	Shared Neighborhood Hits	73
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

LIPA2_HUMAN
NC score	0.023232 (rank : 93)	θ value	0.62314 (rank : 33)
Query Neighborhood Hits	200	Target Neighborhood Hits	1044	Shared Neighborhood Hits	33
SwissProt Accessions	O75334	Gene names	PPFIA2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

MAT1_HUMAN
NC score	0.023160 (rank : 94)	θ value	5.27518 (rank : 115)
Query Neighborhood Hits	200	Target Neighborhood Hits	179	Shared Neighborhood Hits	10
SwissProt Accessions	P51948, Q15817	Gene names	MNAT1, CAP35, MAT1, RNF66
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35) (Cyclin G1-interacting protein) (RING finger protein 66).

TSH2_MOUSE
NC score	0.022973 (rank : 95)	θ value	0.47712 (rank : 30)
Query Neighborhood Hits	200	Target Neighborhood Hits	467	Shared Neighborhood Hits	12
SwissProt Accessions	Q68FE9, Q5DTF1, Q6AXH5, Q9JL71	Gene names	Tshz2, Kiaa4248, Sdccag33l, Tsh2, Zfp218, Znf218
Domain Architecture	No domain graphic available
Description	Teashirt homolog 2 (Zinc finger protein 218) (SDCCAG33-like protein).

GON4L_HUMAN
NC score	0.022773 (rank : 96)	θ value	3.0926 (rank : 76)
Query Neighborhood Hits	200	Target Neighborhood Hits	555	Shared Neighborhood Hits	33
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

ZN638_MOUSE
NC score	0.022697 (rank : 97)	θ value	8.99809 (rank : 200)
Query Neighborhood Hits	200	Target Neighborhood Hits	318	Shared Neighborhood Hits	26
SwissProt Accessions	Q61464, Q6DFV9, Q8C941	Gene names	Znf638, Np220, Zfml
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein).

ELOA1_MOUSE
NC score	0.022690 (rank : 98)	θ value	2.36792 (rank : 60)
Query Neighborhood Hits	200	Target Neighborhood Hits	152	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CB77, Q80VB2, Q9R0Q5	Gene names	Tceb3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

ZFY19_HUMAN
NC score	0.022634 (rank : 99)	θ value	2.36792 (rank : 71)
Query Neighborhood Hits	200	Target Neighborhood Hits	206	Shared Neighborhood Hits	6
SwissProt Accessions	Q96K21, Q86WC2, Q8WU96	Gene names	ZFYVE19, MPFYVE
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19 (MLL partner containing FYVE domain).

BICD2_MOUSE
NC score	0.022335 (rank : 100)	θ value	0.47712 (rank : 27)
Query Neighborhood Hits	200	Target Neighborhood Hits	864	Shared Neighborhood Hits	34
SwissProt Accessions	Q921C5, Q80TU1, Q8BTE3, Q9DCL3	Gene names	Bicd2, Kiaa0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

LIPA2_MOUSE
NC score	0.022229 (rank : 101)	θ value	1.06291 (rank : 40)
Query Neighborhood Hits	200	Target Neighborhood Hits	1282	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

WDR60_MOUSE
NC score	0.021192 (rank : 102)	θ value	6.88961 (rank : 163)
Query Neighborhood Hits	200	Target Neighborhood Hits	344	Shared Neighborhood Hits	29
SwissProt Accessions	Q8C761, Q3UNM4	Gene names	Wdr60
Domain Architecture	No domain graphic available
Description	WD repeat protein 60.

ZN318_MOUSE
NC score	0.021147 (rank : 103)	θ value	5.27518 (rank : 128)
Query Neighborhood Hits	200	Target Neighborhood Hits	642	Shared Neighborhood Hits	39
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

SGOL2_HUMAN
NC score	0.020804 (rank : 104)	θ value	6.88961 (rank : 157)
Query Neighborhood Hits	200	Target Neighborhood Hits	207	Shared Neighborhood Hits	17
SwissProt Accessions	Q562F6, Q53RR9, Q53T20, Q86XY4, Q8IWK2, Q8IZK1, Q8N1Q5, Q96LQ3	Gene names	SGOL2
Domain Architecture	No domain graphic available
Description	Shugoshin-like 2 (Tripin).

FYCO1_HUMAN
NC score	0.020648 (rank : 105)	θ value	0.365318 (rank : 24)
Query Neighborhood Hits	200	Target Neighborhood Hits	1149	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

MAT1_MOUSE
NC score	0.020433 (rank : 106)	θ value	6.88961 (rank : 146)
Query Neighborhood Hits	200	Target Neighborhood Hits	217	Shared Neighborhood Hits	10
SwissProt Accessions	P51949, Q3TZP0, Q9D8A0, Q9D8D2	Gene names	Mnat1, Mat1
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35).

UBXD8_MOUSE
NC score	0.020431 (rank : 107)	θ value	5.27518 (rank : 126)
Query Neighborhood Hits	200	Target Neighborhood Hits	133	Shared Neighborhood Hits	7
SwissProt Accessions	Q3TDN2, Q3U9W2, Q80TP7, Q80W42	Gene names	Ubxd8, Kiaa0887
Domain Architecture	No domain graphic available
Description	UBX domain-containing protein 8.

TCLB2_MOUSE
NC score	0.020127 (rank : 108)	θ value	8.99809 (rank : 194)
Query Neighborhood Hits	200	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	P56841	Gene names	Tcl1b2
Domain Architecture
Description	TCL1B2 protein.

RM03_HUMAN
NC score	0.019874 (rank : 109)	θ value	8.99809 (rank : 188)
Query Neighborhood Hits	200	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	P09001	Gene names	MRPL3, MRL3
Domain Architecture
Description	Mitochondrial 39S ribosomal protein L3 (L3mt) (MRP-L3).

ORC1_HUMAN
NC score	0.019528 (rank : 110)	θ value	5.27518 (rank : 120)
Query Neighborhood Hits	200	Target Neighborhood Hits	102	Shared Neighborhood Hits	16
SwissProt Accessions	Q13415, Q13471, Q5T0F5	Gene names	ORC1L, ORC1, PARC1
Domain Architecture
Description	Origin recognition complex subunit 1 (Replication control protein 1).

SRBS1_HUMAN
NC score	0.019428 (rank : 111)	θ value	2.36792 (rank : 67)
Query Neighborhood Hits	200	Target Neighborhood Hits	396	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

NFH_HUMAN
NC score	0.019200 (rank : 112)	θ value	3.0926 (rank : 82)
Query Neighborhood Hits	200	Target Neighborhood Hits	1242	Shared Neighborhood Hits	64
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

UBXD8_HUMAN
NC score	0.019165 (rank : 113)	θ value	6.88961 (rank : 162)
Query Neighborhood Hits	200	Target Neighborhood Hits	131	Shared Neighborhood Hits	7
SwissProt Accessions	Q96CS3, O94963, Q8IUF2, Q9BRP2, Q9BVM7	Gene names	UBXD8, ETEA, KIAA0887
Domain Architecture	No domain graphic available
Description	UBX domain-containing protein 8 (Protein ETEA).

APC_MOUSE
NC score	0.018756 (rank : 114)	θ value	5.27518 (rank : 107)
Query Neighborhood Hits	200	Target Neighborhood Hits	441	Shared Neighborhood Hits	31
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

VP13A_HUMAN
NC score	0.018750 (rank : 115)	θ value	8.99809 (rank : 196)
Query Neighborhood Hits	200	Target Neighborhood Hits	93	Shared Neighborhood Hits	7
SwissProt Accessions	Q96RL7, Q5JSX9, Q5JSY0, Q5VYR5, Q702P4, Q709D0, Q86YF8, Q96S61, Q9H995, Q9Y2J1	Gene names	VPS13A, CHAC, KIAA0986
Domain Architecture
Description	Vacuolar protein sorting-associated protein 13A (Chorein) (Chorea- acanthocytosis protein).

SYCP1_MOUSE
NC score	0.018608 (rank : 116)	θ value	3.0926 (rank : 84)
Query Neighborhood Hits	200	Target Neighborhood Hits	1456	Shared Neighborhood Hits	58
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

CBP_HUMAN
NC score	0.018567 (rank : 117)	θ value	2.36792 (rank : 57)
Query Neighborhood Hits	200	Target Neighborhood Hits	941	Shared Neighborhood Hits	34
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

NCOR2_MOUSE
NC score	0.018457 (rank : 118)	θ value	3.0926 (rank : 81)
Query Neighborhood Hits	200	Target Neighborhood Hits	790	Shared Neighborhood Hits	38
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

SNCAP_HUMAN
NC score	0.018449 (rank : 119)	θ value	2.36792 (rank : 66)
Query Neighborhood Hits	200	Target Neighborhood Hits	313	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y6H5	Gene names	SNCAIP
Domain Architecture
Description	Synphilin-1 (Alpha-synuclein-interacting protein).

SGOL2_MOUSE
NC score	0.017964 (rank : 120)	θ value	8.99809 (rank : 192)
Query Neighborhood Hits	200	Target Neighborhood Hits	112	Shared Neighborhood Hits	11
SwissProt Accessions	Q7TSY8, Q811I4, Q8C9C4, Q8CGJ4, Q9CS55	Gene names	Sgol2
Domain Architecture	No domain graphic available
Description	Shugoshin-like 2.

FNBP2_HUMAN
NC score	0.017913 (rank : 121)	θ value	0.813845 (rank : 36)
Query Neighborhood Hits	200	Target Neighborhood Hits	432	Shared Neighborhood Hits	16
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

ERCC6_HUMAN
NC score	0.017379 (rank : 122)	θ value	0.62314 (rank : 31)
Query Neighborhood Hits	200	Target Neighborhood Hits	247	Shared Neighborhood Hits	17
SwissProt Accessions	Q03468	Gene names	ERCC6, CSB
Domain Architecture
Description	DNA excision repair protein ERCC-6 (EC 3.6.1.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB).

MYT1_MOUSE
NC score	0.017050 (rank : 123)	θ value	3.0926 (rank : 80)
Query Neighborhood Hits	200	Target Neighborhood Hits	385	Shared Neighborhood Hits	25
SwissProt Accessions	Q8CFC2, O08995, Q8CFH1	Gene names	Myt1, Kiaa0835, Nzf2
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1 (MyT1) (Neural zinc finger factor 2) (NZF-2).

MYH8_HUMAN
NC score	0.016947 (rank : 124)	θ value	1.06291 (rank : 41)
Query Neighborhood Hits	200	Target Neighborhood Hits	1610	Shared Neighborhood Hits	62
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

RWDD1_HUMAN
NC score	0.016853 (rank : 125)	θ value	8.99809 (rank : 190)
Query Neighborhood Hits	200	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H446, Q9Y313, Q9Y6B3	Gene names	RWDD1
Domain Architecture
Description	RWD domain-containing protein 1.

MYO5B_HUMAN
NC score	0.016796 (rank : 126)	θ value	0.279714 (rank : 22)
Query Neighborhood Hits	200	Target Neighborhood Hits	911	Shared Neighborhood Hits	34
SwissProt Accessions	Q9ULV0	Gene names	MYO5B, KIAA1119
Domain Architecture
Description	Myosin-5B (Myosin Vb).

THSD1_HUMAN
NC score	0.016759 (rank : 127)	θ value	3.0926 (rank : 85)
Query Neighborhood Hits	200	Target Neighborhood Hits	136	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NS62, Q6P3U1, Q6UXZ2	Gene names	THSD1, TMTSP
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

RWDD1_MOUSE
NC score	0.016618 (rank : 128)	θ value	8.99809 (rank : 191)
Query Neighborhood Hits	200	Target Neighborhood Hits	33	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CQK7	Gene names	Rwdd1
Domain Architecture
Description	RWD domain-containing protein 1 (IH1).

SETBP_HUMAN
NC score	0.016497 (rank : 129)	θ value	6.88961 (rank : 156)
Query Neighborhood Hits	200	Target Neighborhood Hits	305	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y6X0, Q9UEF3	Gene names	SETBP1, KIAA0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

SMC4_MOUSE
NC score	0.016405 (rank : 130)	θ value	2.36792 (rank : 65)
Query Neighborhood Hits	200	Target Neighborhood Hits	830	Shared Neighborhood Hits	25
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

WDHD1_MOUSE
NC score	0.016350 (rank : 131)	θ value	3.0926 (rank : 87)
Query Neighborhood Hits	200	Target Neighborhood Hits	414	Shared Neighborhood Hits	21
SwissProt Accessions	P59328, Q6P408	Gene names	Wdhd1, And1
Domain Architecture	No domain graphic available
Description	WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA- binding protein 1) (And-1).

CS007_MOUSE
NC score	0.016263 (rank : 132)	θ value	5.27518 (rank : 110)
Query Neighborhood Hits	200	Target Neighborhood Hits	464	Shared Neighborhood Hits	21
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

NCOA6_HUMAN
NC score	0.016219 (rank : 133)	θ value	8.99809 (rank : 184)
Query Neighborhood Hits	200	Target Neighborhood Hits	1202	Shared Neighborhood Hits	40
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

FR1OP_HUMAN
NC score	0.016006 (rank : 134)	θ value	6.88961 (rank : 140)
Query Neighborhood Hits	200	Target Neighborhood Hits	14	Shared Neighborhood Hits	5
SwissProt Accessions	O95684, Q49AI0, Q5R3F6, Q96EW1	Gene names	FGFR1OP, FOP
Domain Architecture	No domain graphic available
Description	FGFR1 oncogene partner.

FA8_MOUSE
NC score	0.015808 (rank : 135)	θ value	1.06291 (rank : 39)
Query Neighborhood Hits	200	Target Neighborhood Hits	100	Shared Neighborhood Hits	6
SwissProt Accessions	Q06194	Gene names	F8, Cf8, F8c
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component).

REV1_HUMAN
NC score	0.015470 (rank : 136)	θ value	4.03905 (rank : 100)
Query Neighborhood Hits	200	Target Neighborhood Hits	56	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBZ9, O95941, Q9C0J4, Q9NUP2	Gene names	REV1L, REV1
Domain Architecture	No domain graphic available
Description	DNA repair protein REV1 (EC 2.7.7.-) (Rev1-like terminal deoxycytidyl transferase) (Alpha integrin-binding protein 80) (AIBP80).

TLN2_HUMAN
NC score	0.015184 (rank : 137)	θ value	5.27518 (rank : 123)
Query Neighborhood Hits	200	Target Neighborhood Hits	157	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y4G6	Gene names	TLN2, KIAA0320
Domain Architecture
Description	Talin-2.

KCTD5_HUMAN
NC score	0.015103 (rank : 138)	θ value	5.27518 (rank : 112)
Query Neighborhood Hits	200	Target Neighborhood Hits	66	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NXV2	Gene names	KCTD5
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD5.

TNAP2_MOUSE
NC score	0.015096 (rank : 139)	θ value	5.27518 (rank : 125)
Query Neighborhood Hits	200	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q61333, Q922G1	Gene names	Tnfaip2
Domain Architecture
Description	Tumor necrosis factor, alpha-induced protein 2 (Primary response gene B94 protein).

KCTD5_MOUSE
NC score	0.015087 (rank : 140)	θ value	5.27518 (rank : 113)
Query Neighborhood Hits	200	Target Neighborhood Hits	64	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VC57	Gene names	Kctd5
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD5.

TLN2_MOUSE
NC score	0.015070 (rank : 141)	θ value	5.27518 (rank : 124)
Query Neighborhood Hits	200	Target Neighborhood Hits	149	Shared Neighborhood Hits	8
SwissProt Accessions	Q71LX4, Q8BWK0	Gene names	Tln2
Domain Architecture	No domain graphic available
Description	Talin-2.

CAC1D_HUMAN
NC score	0.014932 (rank : 142)	θ value	0.279714 (rank : 21)
Query Neighborhood Hits	200	Target Neighborhood Hits	118	Shared Neighborhood Hits	4
SwissProt Accessions	Q01668, Q13916, Q13931	Gene names	CACNA1D, CACH3, CACN4, CACNL1A2, CCHL1A2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1D (Voltage- gated calcium channel subunit alpha Cav1.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 2).

MLH3_HUMAN
NC score	0.014739 (rank : 143)	θ value	6.88961 (rank : 147)
Query Neighborhood Hits	200	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UHC1, P49751, Q56DK9, Q9P292, Q9UHC0	Gene names	MLH3
Domain Architecture
Description	DNA mismatch repair protein Mlh3 (MutL protein homolog 3).

MORC3_HUMAN
NC score	0.014609 (rank : 144)	θ value	5.27518 (rank : 118)
Query Neighborhood Hits	200	Target Neighborhood Hits	489	Shared Neighborhood Hits	23
SwissProt Accessions	Q14149, Q9UEZ2	Gene names	MORC3, KIAA0136, ZCWCC3
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 3 (Zinc finger CW-type coiled- coil domain protein 3).

RGP2_HUMAN
NC score	0.014581 (rank : 145)	θ value	4.03905 (rank : 101)
Query Neighborhood Hits	200	Target Neighborhood Hits	60	Shared Neighborhood Hits	7
SwissProt Accessions	P47736	Gene names	RAP1GAP, RAP1GA1
Domain Architecture
Description	Rap1 GTPase-activating protein 1 (Rap1GAP).

FLIP1_HUMAN
NC score	0.014473 (rank : 146)	θ value	3.0926 (rank : 75)
Query Neighborhood Hits	200	Target Neighborhood Hits	1405	Shared Neighborhood Hits	43
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

E41LA_MOUSE
NC score	0.014164 (rank : 147)	θ value	8.99809 (rank : 178)
Query Neighborhood Hits	200	Target Neighborhood Hits	85	Shared Neighborhood Hits	16
SwissProt Accessions	P52963	Gene names	Epb41l4a, Epb4.1l4, Epb4.1l4a, Epb41l4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

SMG1_MOUSE
NC score	0.014095 (rank : 148)	θ value	6.88961 (rank : 158)
Query Neighborhood Hits	200	Target Neighborhood Hits	212	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BKX6, Q5DU42, Q6ZQC0, Q8BLU4, Q8BWJ5, Q8BXD3	Gene names	Smg1, Kiaa0421
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1).

H6ST2_HUMAN
NC score	0.013929 (rank : 149)	θ value	4.03905 (rank : 94)
Query Neighborhood Hits	200	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q96MM7, Q4VC07, Q6PIC4, Q86SM9, Q8N3T4, Q8NBN4, Q96SJ4	Gene names	HS6ST2
Domain Architecture	No domain graphic available
Description	Heparan-sulfate 6-O-sulfotransferase 2 (EC 2.8.2.-) (HS6ST-2).

FRM4B_MOUSE
NC score	0.013921 (rank : 150)	θ value	5.27518 (rank : 111)
Query Neighborhood Hits	200	Target Neighborhood Hits	109	Shared Neighborhood Hits	12
SwissProt Accessions	Q920B0, Q3V1S1, Q9ESP9	Gene names	Frmd4b
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1) (Golgi- associated band 4.1-like protein) (GOBLIN).

ANK3_HUMAN
NC score	0.013873 (rank : 151)	θ value	0.813845 (rank : 35)
Query Neighborhood Hits	200	Target Neighborhood Hits	853	Shared Neighborhood Hits	50
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

SRBS1_MOUSE
NC score	0.013834 (rank : 152)	θ value	8.99809 (rank : 193)
Query Neighborhood Hits	200	Target Neighborhood Hits	409	Shared Neighborhood Hits	17
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

CMTA1_HUMAN
NC score	0.013466 (rank : 153)	θ value	8.99809 (rank : 172)
Query Neighborhood Hits	200	Target Neighborhood Hits	217	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

CN145_MOUSE
NC score	0.013361 (rank : 154)	θ value	6.88961 (rank : 137)
Query Neighborhood Hits	200	Target Neighborhood Hits	916	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

AIM1_HUMAN
NC score	0.012868 (rank : 155)	θ value	6.88961 (rank : 131)
Query Neighborhood Hits	200	Target Neighborhood Hits	247	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y4K1, O00296, Q5VWJ2	Gene names	AIM1
Domain Architecture
Description	Absent in melanoma 1 protein.

K1718_HUMAN
NC score	0.012848 (rank : 156)	θ value	3.0926 (rank : 78)
Query Neighborhood Hits	200	Target Neighborhood Hits	114	Shared Neighborhood Hits	5
SwissProt Accessions	Q6ZMT4, Q6MZL8, Q9C0E5	Gene names	KIAA1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

KCTD2_HUMAN
NC score	0.012766 (rank : 157)	θ value	8.99809 (rank : 182)
Query Neighborhood Hits	200	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	Q14681	Gene names	KCTD2, KIAA0176
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD2.

UACA_HUMAN
NC score	0.012504 (rank : 158)	θ value	8.99809 (rank : 195)
Query Neighborhood Hits	200	Target Neighborhood Hits	1622	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

BRCA2_MOUSE
NC score	0.012500 (rank : 159)	θ value	8.99809 (rank : 168)
Query Neighborhood Hits	200	Target Neighborhood Hits	222	Shared Neighborhood Hits	18
SwissProt Accessions	P97929, O35922, P97383	Gene names	Brca2, Fancd1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein homolog (Fanconi anemia group D1 protein homolog).

CLMN_MOUSE
NC score	0.012175 (rank : 160)	θ value	2.36792 (rank : 59)
Query Neighborhood Hits	200	Target Neighborhood Hits	180	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C5W0, Q91V71, Q91XT7, Q91XT8, Q91XU9	Gene names	Clmn
Domain Architecture
Description	Calmin.

RLF_HUMAN
NC score	0.011910 (rank : 161)	θ value	0.47712 (rank : 29)
Query Neighborhood Hits	200	Target Neighborhood Hits	775	Shared Neighborhood Hits	18
SwissProt Accessions	Q13129, Q9NU60	Gene names	RLF
Domain Architecture	No domain graphic available
Description	Zinc finger protein Rlf (Rearranged L-myc fusion gene protein) (Zn-15- related protein).

MYH8_MOUSE
NC score	0.011797 (rank : 162)	θ value	8.99809 (rank : 183)
Query Neighborhood Hits	200	Target Neighborhood Hits	1600	Shared Neighborhood Hits	53
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

AZI1_MOUSE
NC score	0.011567 (rank : 163)	θ value	8.99809 (rank : 167)
Query Neighborhood Hits	200	Target Neighborhood Hits	990	Shared Neighborhood Hits	30
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

DNJC1_MOUSE
NC score	0.011529 (rank : 164)	θ value	4.03905 (rank : 89)
Query Neighborhood Hits	200	Target Neighborhood Hits	129	Shared Neighborhood Hits	7
SwissProt Accessions	Q61712	Gene names	Dnajc1, Dnajl1, Mtj1
Domain Architecture
Description	DnaJ homolog subfamily C member 1 (DnaJ protein homolog MTJ1).

POTE8_HUMAN
NC score	0.011151 (rank : 165)	θ value	1.06291 (rank : 42)
Query Neighborhood Hits	200	Target Neighborhood Hits	337	Shared Neighborhood Hits	8
SwissProt Accessions	Q6S8J7, Q6S8J6	Gene names	POTE8
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 8.

PTN13_HUMAN
NC score	0.011066 (rank : 166)	θ value	3.0926 (rank : 83)
Query Neighborhood Hits	200	Target Neighborhood Hits	471	Shared Neighborhood Hits	25
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

DC1L2_HUMAN
NC score	0.010467 (rank : 167)	θ value	6.88961 (rank : 138)
Query Neighborhood Hits	200	Target Neighborhood Hits	39	Shared Neighborhood Hits	3
SwissProt Accessions	O43237, Q8TAT3	Gene names	DYNC1LI2, DNCLI2, LIC2
Domain Architecture
Description	Cytoplasmic dynein 1 light intermediate chain 2 (Dynein light intermediate chain 2, cytosolic) (LIC53/55) (LIC-2).

RHG06_HUMAN
NC score	0.010382 (rank : 168)	θ value	6.88961 (rank : 155)
Query Neighborhood Hits	200	Target Neighborhood Hits	114	Shared Neighborhood Hits	12
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

AP1M2_HUMAN
NC score	0.010010 (rank : 169)	θ value	6.88961 (rank : 133)
Query Neighborhood Hits	200	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y6Q5, Q9BSI8	Gene names	AP1M2
Domain Architecture
Description	AP-1 complex subunit mu-2 (Adaptor-related protein complex 1 mu-2 subunit) (Mu-adaptin 2) (Adaptor protein complex AP-1 mu-2 subunit) (Golgi adaptor HA1/AP1 adaptin mu-2 subunit) (Clathrin assembly protein assembly protein complex 1 medium chain 2) (AP-mu chain family member mu1B).

AP1M2_MOUSE
NC score	0.009934 (rank : 170)	θ value	6.88961 (rank : 134)
Query Neighborhood Hits	200	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WVP1, Q99LA4, Q9CWP7	Gene names	Ap1m2
Domain Architecture
Description	AP-1 complex subunit mu-2 (Adaptor-related protein complex 1 mu-2 subunit) (Mu-adaptin 2) (Adaptor protein complex AP-1 mu-2 subunit) (Golgi adaptor HA1/AP1 adaptin mu-2 subunit) (Clathrin assembly protein assembly protein complex 1 medium chain 2) (AP-mu chain family member mu1B).

NFAT5_MOUSE
NC score	0.009462 (rank : 171)	θ value	6.88961 (rank : 148)
Query Neighborhood Hits	200	Target Neighborhood Hits	162	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WV30	Gene names	Nfat5
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T cell transcription factor NFAT5) (NF-AT5) (Rel domain-containing transcription factor NFAT5).

GRLF1_HUMAN
NC score	0.009260 (rank : 172)	θ value	6.88961 (rank : 142)
Query Neighborhood Hits	200	Target Neighborhood Hits	167	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

YAP1_HUMAN
NC score	0.009179 (rank : 173)	θ value	8.99809 (rank : 197)
Query Neighborhood Hits	200	Target Neighborhood Hits	173	Shared Neighborhood Hits	9
SwissProt Accessions	P46937	Gene names	YAP1, YAP65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

CAC1B_MOUSE
NC score	0.008207 (rank : 174)	θ value	8.99809 (rank : 170)
Query Neighborhood Hits	200	Target Neighborhood Hits	351	Shared Neighborhood Hits	12
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CASP8_MOUSE
NC score	0.008095 (rank : 175)	θ value	6.88961 (rank : 136)
Query Neighborhood Hits	200	Target Neighborhood Hits	57	Shared Neighborhood Hits	3
SwissProt Accessions	O89110, O35669	Gene names	Casp8
Domain Architecture
Description	Caspase-8 precursor (EC 3.4.22.-) (CASP-8) [Contains: Caspase-8 subunit p18; Caspase-8 subunit p10].

RNF34_MOUSE
NC score	0.008055 (rank : 176)	θ value	8.99809 (rank : 189)
Query Neighborhood Hits	200	Target Neighborhood Hits	160	Shared Neighborhood Hits	6
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

PKP1_HUMAN
NC score	0.007925 (rank : 177)	θ value	8.99809 (rank : 187)
Query Neighborhood Hits	200	Target Neighborhood Hits	36	Shared Neighborhood Hits	5
SwissProt Accessions	Q13835, O00645, Q15152	Gene names	PKP1
Domain Architecture
Description	Plakophilin-1 (Band-6 protein) (B6P).

CTND2_HUMAN
NC score	0.007863 (rank : 178)	θ value	8.99809 (rank : 176)
Query Neighborhood Hits	200	Target Neighborhood Hits	333	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

KIF1B_HUMAN
NC score	0.007643 (rank : 179)	θ value	5.27518 (rank : 114)
Query Neighborhood Hits	200	Target Neighborhood Hits	178	Shared Neighborhood Hits	6
SwissProt Accessions	O60333, Q96Q94, Q9BV80, Q9P280	Gene names	KIF1B, KIAA0591, KIAA1448
Domain Architecture
Description	Kinesin-like protein KIF1B (Klp).

FOXJ3_HUMAN
NC score	0.007562 (rank : 180)	θ value	4.03905 (rank : 91)
Query Neighborhood Hits	200	Target Neighborhood Hits	177	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UPW0, Q9NSS7	Gene names	FOXJ3, KIAA1041
Domain Architecture
Description	Forkhead box protein J3.

PER2_HUMAN
NC score	0.007432 (rank : 181)	θ value	8.99809 (rank : 186)
Query Neighborhood Hits	200	Target Neighborhood Hits	170	Shared Neighborhood Hits	9
SwissProt Accessions	O15055	Gene names	PER2, KIAA0347
Domain Architecture
Description	Period circadian protein 2.

GGA3_MOUSE
NC score	0.007275 (rank : 182)	θ value	8.99809 (rank : 180)
Query Neighborhood Hits	200	Target Neighborhood Hits	148	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BMI3, Q80U71	Gene names	Gga3, Kiaa0154
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

JUND_MOUSE
NC score	0.007262 (rank : 183)	θ value	8.99809 (rank : 181)
Query Neighborhood Hits	200	Target Neighborhood Hits	134	Shared Neighborhood Hits	4
SwissProt Accessions	P15066	Gene names	Jund, Jun-d, Jund1
Domain Architecture
Description	Transcription factor jun-D.

KIF1B_MOUSE
NC score	0.007137 (rank : 184)	θ value	6.88961 (rank : 144)
Query Neighborhood Hits	200	Target Neighborhood Hits	167	Shared Neighborhood Hits	4
SwissProt Accessions	Q60575, Q9R0B4, Q9WVE5, Q9Z119	Gene names	Kif1b
Domain Architecture
Description	Kinesin-like protein KIF1B.

SOX2_MOUSE
NC score	0.007005 (rank : 185)	θ value	6.88961 (rank : 160)
Query Neighborhood Hits	200	Target Neighborhood Hits	90	Shared Neighborhood Hits	5
SwissProt Accessions	P48432	Gene names	Sox2, Sox-2
Domain Architecture
Description	Transcription factor SOX-2.

OSBL1_HUMAN
NC score	0.006968 (rank : 186)	θ value	4.03905 (rank : 97)
Query Neighborhood Hits	200	Target Neighborhood Hits	368	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

SOX2_HUMAN
NC score	0.006900 (rank : 187)	θ value	6.88961 (rank : 159)
Query Neighborhood Hits	200	Target Neighborhood Hits	89	Shared Neighborhood Hits	5
SwissProt Accessions	P48431, Q14537	Gene names	SOX2
Domain Architecture
Description	Transcription factor SOX-2.

UBP43_MOUSE
NC score	0.006872 (rank : 188)	θ value	6.88961 (rank : 161)
Query Neighborhood Hits	200	Target Neighborhood Hits	130	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BUM9, Q8VDP5	Gene names	Usp43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

ZEP1_HUMAN
NC score	0.005896 (rank : 189)	θ value	4.03905 (rank : 106)
Query Neighborhood Hits	200	Target Neighborhood Hits	1036	Shared Neighborhood Hits	29
SwissProt Accessions	P15822, Q14122	Gene names	HIVEP1, ZNF40
Domain Architecture	No domain graphic available
Description	Zinc finger protein 40 (Human immunodeficiency virus type I enhancer- binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1).

CHIT1_MOUSE
NC score	0.005548 (rank : 190)	θ value	8.99809 (rank : 171)
Query Neighborhood Hits	200	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D7Q1, Q6QJD2	Gene names	Chit1
Domain Architecture
Description	Chitotriosidase-1 precursor (EC 3.2.1.14) (Chitinase-1).

ITA3_MOUSE
NC score	0.005252 (rank : 191)	θ value	6.88961 (rank : 143)
Query Neighborhood Hits	200	Target Neighborhood Hits	54	Shared Neighborhood Hits	3
SwissProt Accessions	Q62470, Q08441, Q08442	Gene names	Itga3
Domain Architecture
Description	Integrin alpha-3 precursor (Galactoprotein B3) (GAPB3) (VLA-3 alpha chain) (CD49c antigen) [Contains: Integrin alpha-3 heavy chain; Integrin alpha-3 light chain].

ATS8_HUMAN
NC score	0.003837 (rank : 192)	θ value	5.27518 (rank : 108)
Query Neighborhood Hits	200	Target Neighborhood Hits	145	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UP79, Q9NZS0	Gene names	ADAMTS8, METH2
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2) (METH- 8).

CRIM1_HUMAN
NC score	0.003656 (rank : 193)	θ value	8.99809 (rank : 173)
Query Neighborhood Hits	200	Target Neighborhood Hits	362	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

M4K4_HUMAN
NC score	0.003174 (rank : 194)	θ value	4.03905 (rank : 95)
Query Neighborhood Hits	200	Target Neighborhood Hits	1589	Shared Neighborhood Hits	39
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

NR2E3_HUMAN
NC score	0.002662 (rank : 195)	θ value	6.88961 (rank : 151)
Query Neighborhood Hits	200	Target Neighborhood Hits	102	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5X4, Q9UHM4	Gene names	NR2E3, PNR, RNR
Domain Architecture
Description	Photoreceptor-specific nuclear receptor (Retina-specific nuclear receptor).

M4K4_MOUSE
NC score	0.001790 (rank : 196)	θ value	6.88961 (rank : 145)
Query Neighborhood Hits	200	Target Neighborhood Hits	1560	Shared Neighborhood Hits	34
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

CS1A_MOUSE
NC score	0.001654 (rank : 197)	θ value	8.99809 (rank : 174)
Query Neighborhood Hits	200	Target Neighborhood Hits	360	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

CS1B_MOUSE
NC score	0.001578 (rank : 198)	θ value	8.99809 (rank : 175)
Query Neighborhood Hits	200	Target Neighborhood Hits	361	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

ZBTB5_HUMAN
NC score	0.000426 (rank : 199)	θ value	6.88961 (rank : 164)
Query Neighborhood Hits	200	Target Neighborhood Hits	811	Shared Neighborhood Hits	10
SwissProt Accessions	O15062	Gene names	ZBTB5, KIAA0354
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 5.

ZN334_HUMAN
NC score	-0.001563 (rank : 200)	θ value	5.27518 (rank : 129)
Query Neighborhood Hits	200	Target Neighborhood Hits	778	Shared Neighborhood Hits	9
SwissProt Accessions	Q9HCZ1, Q5T6U2, Q9NVW4	Gene names	ZNF334
Domain Architecture
Description	Zinc finger protein 334.

RAF1_HUMAN
NC score	-0.001574 (rank : 201)	θ value	6.88961 (rank : 154)
Query Neighborhood Hits	200	Target Neighborhood Hits	886	Shared Neighborhood Hits	5
SwissProt Accessions	P04049	Gene names	RAF1, RAF
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

ZFP95_HUMAN
NC score	-0.001638 (rank : 202)	θ value	6.88961 (rank : 165)
Query Neighborhood Hits	200	Target Neighborhood Hits	775	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y2L8	Gene names	ZFP95, KIAA1015
Domain Architecture
Description	Zinc finger protein 95 homolog (Zfp-95).

PDPK1_MOUSE
NC score	-0.002406 (rank : 203)	θ value	8.99809 (rank : 185)
Query Neighborhood Hits	200	Target Neighborhood Hits	852	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z2A0, Q9R1D8, Q9R215	Gene names	Pdpk1, Pdk1
Domain Architecture
Description	3-phosphoinositide-dependent protein kinase 1 (EC 2.7.11.1) (mPDK1).