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Network neighborhood for query Sequence : EXOC8_MOUSE

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EXOC8_MOUSE
SwissProt Accessions	Q6PGF7	Gene names	Exoc8
Domain Architecture	No domain graphic available
Description	Exocyst complex component 8 (Exocyst complex 84 kDa subunit).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

EXOC8_HUMAN
θ value	0 (rank : 1)	NC score	0.986347 (rank : 2)
Query Neighborhood Hits	43	Target Neighborhood Hits	46	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IYI6, Q5TE82	Gene names	EXOC8
Domain Architecture	No domain graphic available
Description	Exocyst complex component 8 (Exocyst complex 84 kDa subunit).

EXOC8_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	43	Target Neighborhood Hits	43	Shared Neighborhood Hits	43
SwissProt Accessions	Q6PGF7	Gene names	Exoc8
Domain Architecture	No domain graphic available
Description	Exocyst complex component 8 (Exocyst complex 84 kDa subunit).

GLE1_HUMAN
θ value	0.00298849 (rank : 3)	NC score	0.103526 (rank : 3)
Query Neighborhood Hits	43	Target Neighborhood Hits	445	Shared Neighborhood Hits	12
SwissProt Accessions	Q53GS7, O75458, Q53GT9, Q5VVU1, Q8NCP6, Q9UFL6	Gene names	GLE1L, GLE1
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein) (hGLE1).

TSC1_HUMAN
θ value	0.0736092 (rank : 4)	NC score	0.070724 (rank : 6)
Query Neighborhood Hits	43	Target Neighborhood Hits	765	Shared Neighborhood Hits	19
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

CCD41_MOUSE
θ value	0.365318 (rank : 5)	NC score	0.030365 (rank : 18)
Query Neighborhood Hits	43	Target Neighborhood Hits	1399	Shared Neighborhood Hits	23
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

INVO_HUMAN
θ value	0.47712 (rank : 6)	NC score	0.057184 (rank : 7)
Query Neighborhood Hits	43	Target Neighborhood Hits	636	Shared Neighborhood Hits	16
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

DYNA_HUMAN
θ value	0.813845 (rank : 7)	NC score	0.030633 (rank : 16)
Query Neighborhood Hits	43	Target Neighborhood Hits	1194	Shared Neighborhood Hits	22
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

RILP_MOUSE
θ value	0.813845 (rank : 8)	NC score	0.084075 (rank : 4)
Query Neighborhood Hits	43	Target Neighborhood Hits	257	Shared Neighborhood Hits	12
SwissProt Accessions	Q5ND29, Q80WB8, Q8CHY9	Gene names	Rilp
Domain Architecture	No domain graphic available
Description	Rab-interacting lysosomal protein.

DPOLZ_HUMAN
θ value	1.06291 (rank : 9)	NC score	0.030550 (rank : 17)
Query Neighborhood Hits	43	Target Neighborhood Hits	200	Shared Neighborhood Hits	5
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

ARHG5_HUMAN
θ value	1.38821 (rank : 10)	NC score	0.038685 (rank : 10)
Query Neighborhood Hits	43	Target Neighborhood Hits	172	Shared Neighborhood Hits	9
SwissProt Accessions	Q12774	Gene names	ARHGEF5, TIM
Domain Architecture
Description	Rho guanine nucleotide exchange factor 5 (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (p60 TIM) (Transforming immortalized mammary oncogene).

PKHF1_HUMAN
θ value	1.38821 (rank : 11)	NC score	0.043429 (rank : 8)
Query Neighborhood Hits	43	Target Neighborhood Hits	76	Shared Neighborhood Hits	6
SwissProt Accessions	Q96S99, Q96K11, Q9BUB9	Gene names	PLEKHF1, APPD, LAPF, ZFYVE15
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (PH and FYVE domain-containing protein 1) (Phafin-1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains) (Apoptosis-inducing protein) (Zinc finger FYVE domain-containing protein 15).

RFIP4_HUMAN
θ value	1.38821 (rank : 12)	NC score	0.034929 (rank : 15)
Query Neighborhood Hits	43	Target Neighborhood Hits	785	Shared Neighborhood Hits	19
SwissProt Accessions	Q86YS3, Q8N829, Q8NDT7, Q969D8	Gene names	RAB11FIP4, KIAA1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

RILP_HUMAN
θ value	1.38821 (rank : 13)	NC score	0.077932 (rank : 5)
Query Neighborhood Hits	43	Target Neighborhood Hits	249	Shared Neighborhood Hits	12
SwissProt Accessions	Q96NA2, Q71RE6, Q9BSL3, Q9BYS3	Gene names	RILP
Domain Architecture	No domain graphic available
Description	Rab-interacting lysosomal protein.

PKHA3_MOUSE
θ value	2.36792 (rank : 14)	NC score	0.027372 (rank : 21)
Query Neighborhood Hits	43	Target Neighborhood Hits	67	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ERS4	Gene names	Plekha3, Fapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

SNIP_HUMAN
θ value	2.36792 (rank : 15)	NC score	0.035073 (rank : 14)
Query Neighborhood Hits	43	Target Neighborhood Hits	313	Shared Neighborhood Hits	7
SwissProt Accessions	Q9C0H9, Q8N4W8	Gene names	P140, KIAA1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

DDEF2_HUMAN
θ value	3.0926 (rank : 16)	NC score	0.026105 (rank : 24)
Query Neighborhood Hits	43	Target Neighborhood Hits	599	Shared Neighborhood Hits	11
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
θ value	3.0926 (rank : 17)	NC score	0.025941 (rank : 25)
Query Neighborhood Hits	43	Target Neighborhood Hits	625	Shared Neighborhood Hits	11
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

PKHF1_MOUSE
θ value	3.0926 (rank : 18)	NC score	0.040419 (rank : 9)
Query Neighborhood Hits	43	Target Neighborhood Hits	80	Shared Neighborhood Hits	6
SwissProt Accessions	Q3TB82, Q99M16	Gene names	Plekhf1, Lapf
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains).

PKHF2_HUMAN
θ value	3.0926 (rank : 19)	NC score	0.038559 (rank : 11)
Query Neighborhood Hits	43	Target Neighborhood Hits	75	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H8W4	Gene names	PLEKHF2, ZFYVE18
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2) (PH and FYVE domain-containing protein 2) (Phafin-2) (Zinc finger FYVE domain-containing protein 18).

PKHF2_MOUSE
θ value	3.0926 (rank : 20)	NC score	0.038478 (rank : 12)
Query Neighborhood Hits	43	Target Neighborhood Hits	77	Shared Neighborhood Hits	6
SwissProt Accessions	Q91WB4	Gene names	Plekhf2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2).

CENPE_HUMAN
θ value	4.03905 (rank : 21)	NC score	0.014139 (rank : 38)
Query Neighborhood Hits	43	Target Neighborhood Hits	2060	Shared Neighborhood Hits	28
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

CING_MOUSE
θ value	4.03905 (rank : 22)	NC score	0.022630 (rank : 26)
Query Neighborhood Hits	43	Target Neighborhood Hits	1432	Shared Neighborhood Hits	25
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

ECT2_MOUSE
θ value	4.03905 (rank : 23)	NC score	0.022448 (rank : 27)
Query Neighborhood Hits	43	Target Neighborhood Hits	98	Shared Neighborhood Hits	6
SwissProt Accessions	Q07139	Gene names	Ect2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

ALO17_HUMAN
θ value	5.27518 (rank : 24)	NC score	0.022186 (rank : 28)
Query Neighborhood Hits	43	Target Neighborhood Hits	317	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

ANR15_HUMAN
θ value	5.27518 (rank : 25)	NC score	0.011487 (rank : 42)
Query Neighborhood Hits	43	Target Neighborhood Hits	478	Shared Neighborhood Hits	9
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

BCN1_MOUSE
θ value	5.27518 (rank : 26)	NC score	0.035825 (rank : 13)
Query Neighborhood Hits	43	Target Neighborhood Hits	367	Shared Neighborhood Hits	10
SwissProt Accessions	O88597	Gene names	Becn1
Domain Architecture
Description	Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein).

CP250_MOUSE
θ value	5.27518 (rank : 27)	NC score	0.021950 (rank : 29)
Query Neighborhood Hits	43	Target Neighborhood Hits	1583	Shared Neighborhood Hits	27
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

KPYM_MOUSE
θ value	5.27518 (rank : 28)	NC score	0.016141 (rank : 35)
Query Neighborhood Hits	43	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	P52480, Q64484, Q91YI8	Gene names	Pkm2, Pk3, Pykm
Domain Architecture
Description	Pyruvate kinase isozyme M2 (EC 2.7.1.40).

MYH8_HUMAN
θ value	5.27518 (rank : 29)	NC score	0.012176 (rank : 39)
Query Neighborhood Hits	43	Target Neighborhood Hits	1610	Shared Neighborhood Hits	27
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

DMD_HUMAN
θ value	6.88961 (rank : 30)	NC score	0.015271 (rank : 37)
Query Neighborhood Hits	43	Target Neighborhood Hits	1135	Shared Neighborhood Hits	25
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

DUET_HUMAN
θ value	6.88961 (rank : 31)	NC score	0.005682 (rank : 43)
Query Neighborhood Hits	43	Target Neighborhood Hits	1220	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

NASP_HUMAN
θ value	6.88961 (rank : 32)	NC score	0.027654 (rank : 20)
Query Neighborhood Hits	43	Target Neighborhood Hits	709	Shared Neighborhood Hits	9
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

TRAF5_HUMAN
θ value	6.88961 (rank : 33)	NC score	0.016657 (rank : 34)
Query Neighborhood Hits	43	Target Neighborhood Hits	396	Shared Neighborhood Hits	8
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

ECT2_HUMAN
θ value	8.99809 (rank : 34)	NC score	0.020119 (rank : 30)
Query Neighborhood Hits	43	Target Neighborhood Hits	98	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H8V3, Q9NSV8, Q9NVW9	Gene names	ECT2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

FGD4_HUMAN
θ value	8.99809 (rank : 35)	NC score	0.018044 (rank : 33)
Query Neighborhood Hits	43	Target Neighborhood Hits	219	Shared Neighborhood Hits	13
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

LAMB1_MOUSE
θ value	8.99809 (rank : 36)	NC score	0.011729 (rank : 40)
Query Neighborhood Hits	43	Target Neighborhood Hits	919	Shared Neighborhood Hits	13
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LRSM1_HUMAN
θ value	8.99809 (rank : 37)	NC score	0.015333 (rank : 36)
Query Neighborhood Hits	43	Target Neighborhood Hits	1078	Shared Neighborhood Hits	16
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

MYO5B_HUMAN
θ value	8.99809 (rank : 38)	NC score	0.011709 (rank : 41)
Query Neighborhood Hits	43	Target Neighborhood Hits	911	Shared Neighborhood Hits	21
SwissProt Accessions	Q9ULV0	Gene names	MYO5B, KIAA1119
Domain Architecture
Description	Myosin-5B (Myosin Vb).

NDEL1_HUMAN
θ value	8.99809 (rank : 39)	NC score	0.027150 (rank : 22)
Query Neighborhood Hits	43	Target Neighborhood Hits	415	Shared Neighborhood Hits	14
SwissProt Accessions	Q9GZM8, Q86T80, Q8TAR7, Q9UH50	Gene names	NDEL1, EOPA, MITAP1, NUDEL
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE-like 1 (Protein Nudel) (Mitosin- associated protein 1).

NDEL1_MOUSE
θ value	8.99809 (rank : 40)	NC score	0.027103 (rank : 23)
Query Neighborhood Hits	43	Target Neighborhood Hits	420	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ERR1, Q9D0Q4, Q9EPT6	Gene names	Ndel1, Nudel
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE-like 1 (Protein Nudel) (Protein mNudE-like) (mNudE-L).

SNIP_MOUSE
θ value	8.99809 (rank : 41)	NC score	0.029151 (rank : 19)
Query Neighborhood Hits	43	Target Neighborhood Hits	319	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QWI6, O70298	Gene names	P140, Kiaa1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

TMCC1_HUMAN
θ value	8.99809 (rank : 42)	NC score	0.018743 (rank : 31)
Query Neighborhood Hits	43	Target Neighborhood Hits	337	Shared Neighborhood Hits	12
SwissProt Accessions	O94876, Q68E06, Q8IXM8	Gene names	TMCC1, KIAA0779
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 1.

WWC3_HUMAN
θ value	8.99809 (rank : 43)	NC score	0.018417 (rank : 32)
Query Neighborhood Hits	43	Target Neighborhood Hits	193	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ULE0, Q659C1, Q9BTQ1	Gene names	WWC3, KIAA1280
Domain Architecture	No domain graphic available
Description	WWC family member 3.

Hits sorted by NC score

EXOC8_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	43	Target Neighborhood Hits	43	Shared Neighborhood Hits	43
SwissProt Accessions	Q6PGF7	Gene names	Exoc8
Domain Architecture	No domain graphic available
Description	Exocyst complex component 8 (Exocyst complex 84 kDa subunit).

EXOC8_HUMAN
NC score	0.986347 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	43	Target Neighborhood Hits	46	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IYI6, Q5TE82	Gene names	EXOC8
Domain Architecture	No domain graphic available
Description	Exocyst complex component 8 (Exocyst complex 84 kDa subunit).

GLE1_HUMAN
NC score	0.103526 (rank : 3)	θ value	0.00298849 (rank : 3)
Query Neighborhood Hits	43	Target Neighborhood Hits	445	Shared Neighborhood Hits	12
SwissProt Accessions	Q53GS7, O75458, Q53GT9, Q5VVU1, Q8NCP6, Q9UFL6	Gene names	GLE1L, GLE1
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein) (hGLE1).

RILP_MOUSE
NC score	0.084075 (rank : 4)	θ value	0.813845 (rank : 8)
Query Neighborhood Hits	43	Target Neighborhood Hits	257	Shared Neighborhood Hits	12
SwissProt Accessions	Q5ND29, Q80WB8, Q8CHY9	Gene names	Rilp
Domain Architecture	No domain graphic available
Description	Rab-interacting lysosomal protein.

RILP_HUMAN
NC score	0.077932 (rank : 5)	θ value	1.38821 (rank : 13)
Query Neighborhood Hits	43	Target Neighborhood Hits	249	Shared Neighborhood Hits	12
SwissProt Accessions	Q96NA2, Q71RE6, Q9BSL3, Q9BYS3	Gene names	RILP
Domain Architecture	No domain graphic available
Description	Rab-interacting lysosomal protein.

TSC1_HUMAN
NC score	0.070724 (rank : 6)	θ value	0.0736092 (rank : 4)
Query Neighborhood Hits	43	Target Neighborhood Hits	765	Shared Neighborhood Hits	19
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

INVO_HUMAN
NC score	0.057184 (rank : 7)	θ value	0.47712 (rank : 6)
Query Neighborhood Hits	43	Target Neighborhood Hits	636	Shared Neighborhood Hits	16
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

PKHF1_HUMAN
NC score	0.043429 (rank : 8)	θ value	1.38821 (rank : 11)
Query Neighborhood Hits	43	Target Neighborhood Hits	76	Shared Neighborhood Hits	6
SwissProt Accessions	Q96S99, Q96K11, Q9BUB9	Gene names	PLEKHF1, APPD, LAPF, ZFYVE15
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (PH and FYVE domain-containing protein 1) (Phafin-1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains) (Apoptosis-inducing protein) (Zinc finger FYVE domain-containing protein 15).

PKHF1_MOUSE
NC score	0.040419 (rank : 9)	θ value	3.0926 (rank : 18)
Query Neighborhood Hits	43	Target Neighborhood Hits	80	Shared Neighborhood Hits	6
SwissProt Accessions	Q3TB82, Q99M16	Gene names	Plekhf1, Lapf
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains).

ARHG5_HUMAN
NC score	0.038685 (rank : 10)	θ value	1.38821 (rank : 10)
Query Neighborhood Hits	43	Target Neighborhood Hits	172	Shared Neighborhood Hits	9
SwissProt Accessions	Q12774	Gene names	ARHGEF5, TIM
Domain Architecture
Description	Rho guanine nucleotide exchange factor 5 (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (p60 TIM) (Transforming immortalized mammary oncogene).

PKHF2_HUMAN
NC score	0.038559 (rank : 11)	θ value	3.0926 (rank : 19)
Query Neighborhood Hits	43	Target Neighborhood Hits	75	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H8W4	Gene names	PLEKHF2, ZFYVE18
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2) (PH and FYVE domain-containing protein 2) (Phafin-2) (Zinc finger FYVE domain-containing protein 18).

PKHF2_MOUSE
NC score	0.038478 (rank : 12)	θ value	3.0926 (rank : 20)
Query Neighborhood Hits	43	Target Neighborhood Hits	77	Shared Neighborhood Hits	6
SwissProt Accessions	Q91WB4	Gene names	Plekhf2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2).

BCN1_MOUSE
NC score	0.035825 (rank : 13)	θ value	5.27518 (rank : 26)
Query Neighborhood Hits	43	Target Neighborhood Hits	367	Shared Neighborhood Hits	10
SwissProt Accessions	O88597	Gene names	Becn1
Domain Architecture
Description	Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein).

SNIP_HUMAN
NC score	0.035073 (rank : 14)	θ value	2.36792 (rank : 15)
Query Neighborhood Hits	43	Target Neighborhood Hits	313	Shared Neighborhood Hits	7
SwissProt Accessions	Q9C0H9, Q8N4W8	Gene names	P140, KIAA1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

RFIP4_HUMAN
NC score	0.034929 (rank : 15)	θ value	1.38821 (rank : 12)
Query Neighborhood Hits	43	Target Neighborhood Hits	785	Shared Neighborhood Hits	19
SwissProt Accessions	Q86YS3, Q8N829, Q8NDT7, Q969D8	Gene names	RAB11FIP4, KIAA1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

DYNA_HUMAN
NC score	0.030633 (rank : 16)	θ value	0.813845 (rank : 7)
Query Neighborhood Hits	43	Target Neighborhood Hits	1194	Shared Neighborhood Hits	22
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

DPOLZ_HUMAN
NC score	0.030550 (rank : 17)	θ value	1.06291 (rank : 9)
Query Neighborhood Hits	43	Target Neighborhood Hits	200	Shared Neighborhood Hits	5
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

CCD41_MOUSE
NC score	0.030365 (rank : 18)	θ value	0.365318 (rank : 5)
Query Neighborhood Hits	43	Target Neighborhood Hits	1399	Shared Neighborhood Hits	23
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

SNIP_MOUSE
NC score	0.029151 (rank : 19)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	43	Target Neighborhood Hits	319	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QWI6, O70298	Gene names	P140, Kiaa1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

NASP_HUMAN
NC score	0.027654 (rank : 20)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	43	Target Neighborhood Hits	709	Shared Neighborhood Hits	9
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

PKHA3_MOUSE
NC score	0.027372 (rank : 21)	θ value	2.36792 (rank : 14)
Query Neighborhood Hits	43	Target Neighborhood Hits	67	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ERS4	Gene names	Plekha3, Fapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

NDEL1_HUMAN
NC score	0.027150 (rank : 22)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	43	Target Neighborhood Hits	415	Shared Neighborhood Hits	14
SwissProt Accessions	Q9GZM8, Q86T80, Q8TAR7, Q9UH50	Gene names	NDEL1, EOPA, MITAP1, NUDEL
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE-like 1 (Protein Nudel) (Mitosin- associated protein 1).

NDEL1_MOUSE
NC score	0.027103 (rank : 23)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	43	Target Neighborhood Hits	420	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ERR1, Q9D0Q4, Q9EPT6	Gene names	Ndel1, Nudel
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE-like 1 (Protein Nudel) (Protein mNudE-like) (mNudE-L).

DDEF2_HUMAN
NC score	0.026105 (rank : 24)	θ value	3.0926 (rank : 16)
Query Neighborhood Hits	43	Target Neighborhood Hits	599	Shared Neighborhood Hits	11
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
NC score	0.025941 (rank : 25)	θ value	3.0926 (rank : 17)
Query Neighborhood Hits	43	Target Neighborhood Hits	625	Shared Neighborhood Hits	11
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

CING_MOUSE
NC score	0.022630 (rank : 26)	θ value	4.03905 (rank : 22)
Query Neighborhood Hits	43	Target Neighborhood Hits	1432	Shared Neighborhood Hits	25
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

ECT2_MOUSE
NC score	0.022448 (rank : 27)	θ value	4.03905 (rank : 23)
Query Neighborhood Hits	43	Target Neighborhood Hits	98	Shared Neighborhood Hits	6
SwissProt Accessions	Q07139	Gene names	Ect2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

ALO17_HUMAN
NC score	0.022186 (rank : 28)	θ value	5.27518 (rank : 24)
Query Neighborhood Hits	43	Target Neighborhood Hits	317	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

CP250_MOUSE
NC score	0.021950 (rank : 29)	θ value	5.27518 (rank : 27)
Query Neighborhood Hits	43	Target Neighborhood Hits	1583	Shared Neighborhood Hits	27
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

ECT2_HUMAN
NC score	0.020119 (rank : 30)	θ value	8.99809 (rank : 34)
Query Neighborhood Hits	43	Target Neighborhood Hits	98	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H8V3, Q9NSV8, Q9NVW9	Gene names	ECT2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

TMCC1_HUMAN
NC score	0.018743 (rank : 31)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	43	Target Neighborhood Hits	337	Shared Neighborhood Hits	12
SwissProt Accessions	O94876, Q68E06, Q8IXM8	Gene names	TMCC1, KIAA0779
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 1.

WWC3_HUMAN
NC score	0.018417 (rank : 32)	θ value	8.99809 (rank : 43)
Query Neighborhood Hits	43	Target Neighborhood Hits	193	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ULE0, Q659C1, Q9BTQ1	Gene names	WWC3, KIAA1280
Domain Architecture	No domain graphic available
Description	WWC family member 3.

FGD4_HUMAN
NC score	0.018044 (rank : 33)	θ value	8.99809 (rank : 35)
Query Neighborhood Hits	43	Target Neighborhood Hits	219	Shared Neighborhood Hits	13
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

TRAF5_HUMAN
NC score	0.016657 (rank : 34)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	43	Target Neighborhood Hits	396	Shared Neighborhood Hits	8
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

KPYM_MOUSE
NC score	0.016141 (rank : 35)	θ value	5.27518 (rank : 28)
Query Neighborhood Hits	43	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	P52480, Q64484, Q91YI8	Gene names	Pkm2, Pk3, Pykm
Domain Architecture
Description	Pyruvate kinase isozyme M2 (EC 2.7.1.40).

LRSM1_HUMAN
NC score	0.015333 (rank : 36)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	43	Target Neighborhood Hits	1078	Shared Neighborhood Hits	16
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

DMD_HUMAN
NC score	0.015271 (rank : 37)	θ value	6.88961 (rank : 30)
Query Neighborhood Hits	43	Target Neighborhood Hits	1135	Shared Neighborhood Hits	25
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

CENPE_HUMAN
NC score	0.014139 (rank : 38)	θ value	4.03905 (rank : 21)
Query Neighborhood Hits	43	Target Neighborhood Hits	2060	Shared Neighborhood Hits	28
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

MYH8_HUMAN
NC score	0.012176 (rank : 39)	θ value	5.27518 (rank : 29)
Query Neighborhood Hits	43	Target Neighborhood Hits	1610	Shared Neighborhood Hits	27
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

LAMB1_MOUSE
NC score	0.011729 (rank : 40)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	43	Target Neighborhood Hits	919	Shared Neighborhood Hits	13
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

MYO5B_HUMAN
NC score	0.011709 (rank : 41)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	43	Target Neighborhood Hits	911	Shared Neighborhood Hits	21
SwissProt Accessions	Q9ULV0	Gene names	MYO5B, KIAA1119
Domain Architecture
Description	Myosin-5B (Myosin Vb).

ANR15_HUMAN
NC score	0.011487 (rank : 42)	θ value	5.27518 (rank : 25)
Query Neighborhood Hits	43	Target Neighborhood Hits	478	Shared Neighborhood Hits	9
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

DUET_HUMAN
NC score	0.005682 (rank : 43)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	43	Target Neighborhood Hits	1220	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).