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Network neighborhood for query Sequence : RHG06_HUMAN

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RHG06_HUMAN
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RHG06_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	114	Target Neighborhood Hits	114	Shared Neighborhood Hits	114
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RHG06_MOUSE
θ value	0 (rank : 2)	NC score	0.994230 (rank : 2)
Query Neighborhood Hits	114	Target Neighborhood Hits	105	Shared Neighborhood Hits	73
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

SRGP2_HUMAN
θ value	2.06002e-20 (rank : 3)	NC score	0.719414 (rank : 28)
Query Neighborhood Hits	114	Target Neighborhood Hits	331	Shared Neighborhood Hits	67
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

RHG01_HUMAN
θ value	2.69047e-20 (rank : 4)	NC score	0.799530 (rank : 4)
Query Neighborhood Hits	114	Target Neighborhood Hits	75	Shared Neighborhood Hits	62
SwissProt Accessions	Q07960	Gene names	ARHGAP1, CDC42GAP, RHOGAP1
Domain Architecture
Description	Rho-GTPase-activating protein 1 (GTPase-activating protein rhoOGAP) (Rho-related small GTPase protein activator) (CDC42 GTPase-activating protein) (p50-RhoGAP).

CHIN_HUMAN
θ value	7.82807e-20 (rank : 5)	NC score	0.722793 (rank : 26)
Query Neighborhood Hits	114	Target Neighborhood Hits	227	Shared Neighborhood Hits	63
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIN_MOUSE
θ value	5.07402e-19 (rank : 6)	NC score	0.723863 (rank : 24)
Query Neighborhood Hits	114	Target Neighborhood Hits	229	Shared Neighborhood Hits	64
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

SRGP2_MOUSE
θ value	5.07402e-19 (rank : 7)	NC score	0.710916 (rank : 33)
Query Neighborhood Hits	114	Target Neighborhood Hits	324	Shared Neighborhood Hits	65
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

RHG07_HUMAN
θ value	1.92812e-18 (rank : 8)	NC score	0.733934 (rank : 21)
Query Neighborhood Hits	114	Target Neighborhood Hits	108	Shared Neighborhood Hits	64
SwissProt Accessions	Q96QB1, O14868, O43199, Q9C0E0	Gene names	DLC1, ARHGAP7, KIAA1723, STARD12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein) (Dlc-1) (HP protein) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

RHG12_HUMAN
θ value	5.60996e-18 (rank : 9)	NC score	0.785582 (rank : 8)
Query Neighborhood Hits	114	Target Neighborhood Hits	190	Shared Neighborhood Hits	61
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

3BP1_HUMAN
θ value	7.32683e-18 (rank : 10)	NC score	0.789867 (rank : 6)
Query Neighborhood Hits	114	Target Neighborhood Hits	376	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

RHG12_MOUSE
θ value	1.24977e-17 (rank : 11)	NC score	0.783693 (rank : 9)
Query Neighborhood Hits	114	Target Neighborhood Hits	204	Shared Neighborhood Hits	64
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RHG07_MOUSE
θ value	1.63225e-17 (rank : 12)	NC score	0.736290 (rank : 20)
Query Neighborhood Hits	114	Target Neighborhood Hits	103	Shared Neighborhood Hits	62
SwissProt Accessions	Q9R0Z9, Q8R541	Gene names	Dlc1, Arhgap7, Stard12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein homolog) (Dlc-1) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

3BP1_MOUSE
θ value	1.80466e-16 (rank : 13)	NC score	0.809581 (rank : 3)
Query Neighborhood Hits	114	Target Neighborhood Hits	238	Shared Neighborhood Hits	66
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

GMIP_MOUSE
θ value	3.07829e-16 (rank : 14)	NC score	0.790769 (rank : 5)
Query Neighborhood Hits	114	Target Neighborhood Hits	202	Shared Neighborhood Hits	63
SwissProt Accessions	Q6PGG2, Q6P9S3	Gene names	Gmip
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

RHG25_MOUSE
θ value	3.07829e-16 (rank : 15)	NC score	0.723168 (rank : 25)
Query Neighborhood Hits	114	Target Neighborhood Hits	492	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

STAR8_MOUSE
θ value	3.07829e-16 (rank : 16)	NC score	0.701657 (rank : 36)
Query Neighborhood Hits	114	Target Neighborhood Hits	101	Shared Neighborhood Hits	60
SwissProt Accessions	Q8K031, Q3UZC7, Q6A0A8, Q6P5E0, Q8R3X8	Gene names	Stard8, Kiaa0189
Domain Architecture	No domain graphic available
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

CHIO_MOUSE
θ value	4.02038e-16 (rank : 17)	NC score	0.746619 (rank : 18)
Query Neighborhood Hits	114	Target Neighborhood Hits	130	Shared Neighborhood Hits	61
SwissProt Accessions	Q80XD1, Q9D9W2, Q9ER57	Gene names	Chn2, Arhgap3, Bch
Domain Architecture	No domain graphic available
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

RHG25_HUMAN
θ value	4.02038e-16 (rank : 18)	NC score	0.699747 (rank : 37)
Query Neighborhood Hits	114	Target Neighborhood Hits	550	Shared Neighborhood Hits	64
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

CHIO_HUMAN
θ value	5.25075e-16 (rank : 19)	NC score	0.715408 (rank : 32)
Query Neighborhood Hits	114	Target Neighborhood Hits	220	Shared Neighborhood Hits	62
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

MYO9B_HUMAN
θ value	6.85773e-16 (rank : 20)	NC score	0.408678 (rank : 58)
Query Neighborhood Hits	114	Target Neighborhood Hits	641	Shared Neighborhood Hits	72
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

MYO9B_MOUSE
θ value	8.95645e-16 (rank : 21)	NC score	0.413929 (rank : 57)
Query Neighborhood Hits	114	Target Neighborhood Hits	311	Shared Neighborhood Hits	70
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

RHG08_HUMAN
θ value	1.16975e-15 (rank : 22)	NC score	0.768869 (rank : 16)
Query Neighborhood Hits	114	Target Neighborhood Hits	88	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NSG0, O75983, O95695, Q96RW1, Q96RW2, Q9HA49, Q9HC46, Q9NVX8, Q9NXL1, Q9UH20	Gene names	ARHGAP8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

FNBP2_HUMAN
θ value	2.60593e-15 (rank : 23)	NC score	0.692808 (rank : 40)
Query Neighborhood Hits	114	Target Neighborhood Hits	432	Shared Neighborhood Hits	65
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

RHG08_MOUSE
θ value	2.60593e-15 (rank : 24)	NC score	0.772893 (rank : 14)
Query Neighborhood Hits	114	Target Neighborhood Hits	73	Shared Neighborhood Hits	62
SwissProt Accessions	Q9CXP4, Q99JY7	Gene names	Arhgap8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RBP1_MOUSE
θ value	3.40345e-15 (rank : 25)	NC score	0.715677 (rank : 31)
Query Neighborhood Hits	114	Target Neighborhood Hits	493	Shared Neighborhood Hits	61
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

STAR8_HUMAN
θ value	3.40345e-15 (rank : 26)	NC score	0.691475 (rank : 42)
Query Neighborhood Hits	114	Target Neighborhood Hits	216	Shared Neighborhood Hits	65
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

ABR_HUMAN
θ value	4.44505e-15 (rank : 27)	NC score	0.710661 (rank : 34)
Query Neighborhood Hits	114	Target Neighborhood Hits	166	Shared Neighborhood Hits	65
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

TCGAP_MOUSE
θ value	4.44505e-15 (rank : 28)	NC score	0.741170 (rank : 19)
Query Neighborhood Hits	114	Target Neighborhood Hits	409	Shared Neighborhood Hits	70
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

RHG04_HUMAN
θ value	9.90251e-15 (rank : 29)	NC score	0.720618 (rank : 27)
Query Neighborhood Hits	114	Target Neighborhood Hits	307	Shared Neighborhood Hits	66
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

TCGAP_HUMAN
θ value	9.90251e-15 (rank : 30)	NC score	0.659217 (rank : 47)
Query Neighborhood Hits	114	Target Neighborhood Hits	872	Shared Neighborhood Hits	77
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

BCR_HUMAN
θ value	2.20605e-14 (rank : 31)	NC score	0.693040 (rank : 39)
Query Neighborhood Hits	114	Target Neighborhood Hits	204	Shared Neighborhood Hits	66
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

STA13_MOUSE
θ value	3.76295e-14 (rank : 32)	NC score	0.683730 (rank : 46)
Query Neighborhood Hits	114	Target Neighborhood Hits	89	Shared Neighborhood Hits	59
SwissProt Accessions	Q923Q2, Q8K369	Gene names	Stard13
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13).

GMIP_HUMAN
θ value	1.42992e-13 (rank : 33)	NC score	0.779891 (rank : 10)
Query Neighborhood Hits	114	Target Neighborhood Hits	225	Shared Neighborhood Hits	64
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

RBP1_HUMAN
θ value	1.86753e-13 (rank : 34)	NC score	0.692204 (rank : 41)
Query Neighborhood Hits	114	Target Neighborhood Hits	521	Shared Neighborhood Hits	61
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

RGAP1_HUMAN
θ value	1.86753e-13 (rank : 35)	NC score	0.777791 (rank : 12)
Query Neighborhood Hits	114	Target Neighborhood Hits	189	Shared Neighborhood Hits	61
SwissProt Accessions	Q9H0H5, Q6PJ26, Q9NWN2, Q9P250, Q9P2W2	Gene names	RACGAP1, KIAA1478, MGCRACGAP
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

CE005_MOUSE
θ value	2.43908e-13 (rank : 36)	NC score	0.643785 (rank : 49)
Query Neighborhood Hits	114	Target Neighborhood Hits	238	Shared Neighborhood Hits	62
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

SRGP1_HUMAN
θ value	3.18553e-13 (rank : 37)	NC score	0.688818 (rank : 44)
Query Neighborhood Hits	114	Target Neighborhood Hits	390	Shared Neighborhood Hits	64
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

CE005_HUMAN
θ value	4.16044e-13 (rank : 38)	NC score	0.645732 (rank : 48)
Query Neighborhood Hits	114	Target Neighborhood Hits	213	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

CEND3_MOUSE
θ value	4.16044e-13 (rank : 39)	NC score	0.598379 (rank : 51)
Query Neighborhood Hits	114	Target Neighborhood Hits	228	Shared Neighborhood Hits	62
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

STA13_HUMAN
θ value	5.43371e-13 (rank : 40)	NC score	0.688082 (rank : 45)
Query Neighborhood Hits	114	Target Neighborhood Hits	89	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y3M8, Q5HYH1, Q5TAE3, Q6UN61, Q86TP6, Q86WQ3, Q86XT1	Gene names	STARD13, DLC2, GT650
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13) (46H23.2) (Deleted in liver cancer protein 2) (Rho GTPase-activating protein).

TAGAP_HUMAN
θ value	5.43371e-13 (rank : 41)	NC score	0.733744 (rank : 22)
Query Neighborhood Hits	114	Target Neighborhood Hits	82	Shared Neighborhood Hits	60
SwissProt Accessions	Q8N103, Q2NKM8, Q8NI40, Q96KZ2, Q96QA2	Gene names	TAGAP, TAGAP1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

RHG18_HUMAN
θ value	7.09661e-13 (rank : 42)	NC score	0.778129 (rank : 11)
Query Neighborhood Hits	114	Target Neighborhood Hits	90	Shared Neighborhood Hits	61
SwissProt Accessions	Q8N392, Q58EZ3, Q6P679, Q6PJD7, Q96S64	Gene names	ARHGAP18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18 (MacGAP).

RHG26_HUMAN
θ value	9.26847e-13 (rank : 43)	NC score	0.690301 (rank : 43)
Query Neighborhood Hits	114	Target Neighborhood Hits	281	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

CEND3_HUMAN
θ value	1.58096e-12 (rank : 44)	NC score	0.587288 (rank : 52)
Query Neighborhood Hits	114	Target Neighborhood Hits	275	Shared Neighborhood Hits	65
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

RGAP1_MOUSE
θ value	2.69671e-12 (rank : 45)	NC score	0.768998 (rank : 15)
Query Neighborhood Hits	114	Target Neighborhood Hits	185	Shared Neighborhood Hits	62
SwissProt Accessions	Q9WVM1, Q3THR5, Q3TI41, Q3TM81	Gene names	Racgap1, Mgcracgap
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RHG18_MOUSE
θ value	3.52202e-12 (rank : 46)	NC score	0.775499 (rank : 13)
Query Neighborhood Hits	114	Target Neighborhood Hits	110	Shared Neighborhood Hits	62
SwissProt Accessions	Q8K0Q5, Q8BP03, Q8R196	Gene names	Arhgap18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18.

TAGAP_MOUSE
θ value	1.02475e-11 (rank : 47)	NC score	0.731686 (rank : 23)
Query Neighborhood Hits	114	Target Neighborhood Hits	83	Shared Neighborhood Hits	61
SwissProt Accessions	Q8K2L9, Q920D6	Gene names	Tagap, Tagap1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

CEND2_HUMAN
θ value	1.33837e-11 (rank : 48)	NC score	0.624449 (rank : 50)
Query Neighborhood Hits	114	Target Neighborhood Hits	166	Shared Neighborhood Hits	60
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

GRLF1_HUMAN
θ value	1.33837e-11 (rank : 49)	NC score	0.746671 (rank : 17)
Query Neighborhood Hits	114	Target Neighborhood Hits	167	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

RHG09_HUMAN
θ value	3.89403e-11 (rank : 50)	NC score	0.789746 (rank : 7)
Query Neighborhood Hits	114	Target Neighborhood Hits	186	Shared Neighborhood Hits	62
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

CEND1_HUMAN
θ value	6.64225e-11 (rank : 51)	NC score	0.514064 (rank : 56)
Query Neighborhood Hits	114	Target Neighborhood Hits	284	Shared Neighborhood Hits	57
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

CEND1_MOUSE
θ value	6.64225e-11 (rank : 52)	NC score	0.532979 (rank : 55)
Query Neighborhood Hits	114	Target Neighborhood Hits	260	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

OPHN1_MOUSE
θ value	8.67504e-11 (rank : 53)	NC score	0.718867 (rank : 29)
Query Neighborhood Hits	114	Target Neighborhood Hits	174	Shared Neighborhood Hits	63
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

RHG05_MOUSE
θ value	1.133e-10 (rank : 54)	NC score	0.710540 (rank : 35)
Query Neighborhood Hits	114	Target Neighborhood Hits	165	Shared Neighborhood Hits	62
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

OPHN1_HUMAN
θ value	4.30538e-10 (rank : 55)	NC score	0.717573 (rank : 30)
Query Neighborhood Hits	114	Target Neighborhood Hits	161	Shared Neighborhood Hits	64
SwissProt Accessions	O60890, Q5JQ81, Q8WX47	Gene names	OPHN1
Domain Architecture
Description	Oligophrenin 1.

RHG05_HUMAN
θ value	2.13673e-09 (rank : 56)	NC score	0.697146 (rank : 38)
Query Neighborhood Hits	114	Target Neighborhood Hits	158	Shared Neighborhood Hits	62
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

K1688_HUMAN
θ value	8.40245e-06 (rank : 57)	NC score	0.543386 (rank : 54)
Query Neighborhood Hits	114	Target Neighborhood Hits	217	Shared Neighborhood Hits	64
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

K1688_MOUSE
θ value	8.40245e-06 (rank : 58)	NC score	0.555386 (rank : 53)
Query Neighborhood Hits	114	Target Neighborhood Hits	188	Shared Neighborhood Hits	62
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

OCRL_HUMAN
θ value	8.40245e-06 (rank : 59)	NC score	0.344616 (rank : 60)
Query Neighborhood Hits	114	Target Neighborhood Hits	77	Shared Neighborhood Hits	51
SwissProt Accessions	Q01968, O60800, Q15684, Q15774, Q5JQF1, Q5JQF2, Q9UJG5, Q9UMA5	Gene names	OCRL, INPP5F, OCRL1
Domain Architecture
Description	Inositol polyphosphate 5-phosphatase OCRL-1 (EC 3.1.3.36) (Lowe oculocerebrorenal syndrome protein).

P85A_HUMAN
θ value	0.000602161 (rank : 60)	NC score	0.350449 (rank : 59)
Query Neighborhood Hits	114	Target Neighborhood Hits	479	Shared Neighborhood Hits	61
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

I5P2_HUMAN
θ value	0.0113563 (rank : 61)	NC score	0.336942 (rank : 61)
Query Neighborhood Hits	114	Target Neighborhood Hits	86	Shared Neighborhood Hits	52
SwissProt Accessions	P32019, Q5VSG9, Q5VSH0, Q5VSH1, Q658Q5, Q6P6D4, Q6PD53, Q86YE1	Gene names	INPP5B
Domain Architecture	No domain graphic available
Description	Type II inositol-1,4,5-trisphosphate 5-phosphatase precursor (EC 3.1.3.36) (Phosphoinositide 5-phosphatase) (5PTase) (75 kDa inositol polyphosphate-5-phosphatase).

HAIR_MOUSE
θ value	0.0148317 (rank : 62)	NC score	0.046623 (rank : 107)
Query Neighborhood Hits	114	Target Neighborhood Hits	97	Shared Neighborhood Hits	6
SwissProt Accessions	Q61645, Q80Y47	Gene names	Hr
Domain Architecture
Description	Protein hairless.

EFS_HUMAN
θ value	0.0330416 (rank : 63)	NC score	0.055497 (rank : 85)
Query Neighborhood Hits	114	Target Neighborhood Hits	348	Shared Neighborhood Hits	16
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

P85A_MOUSE
θ value	0.125558 (rank : 64)	NC score	0.335745 (rank : 62)
Query Neighborhood Hits	114	Target Neighborhood Hits	435	Shared Neighborhood Hits	61
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

CD2L7_HUMAN
θ value	0.21417 (rank : 65)	NC score	0.002109 (rank : 150)
Query Neighborhood Hits	114	Target Neighborhood Hits	1275	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

DCR1A_MOUSE
θ value	0.21417 (rank : 66)	NC score	0.042726 (rank : 109)
Query Neighborhood Hits	114	Target Neighborhood Hits	59	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JIC3, Q571H5, Q6GQR6	Gene names	Dclre1a, Kiaa0086, Snm1, Snm1a
Domain Architecture	No domain graphic available
Description	DNA cross-link repair 1A protein.

DYDC2_HUMAN
θ value	0.365318 (rank : 67)	NC score	0.073722 (rank : 69)
Query Neighborhood Hits	114	Target Neighborhood Hits	55	Shared Neighborhood Hits	3
SwissProt Accessions	Q96IM9, Q5QP07, Q5QP11	Gene names	DYDC2
Domain Architecture	No domain graphic available
Description	DPY30 domain-containing protein 2.

KAP1_HUMAN
θ value	0.62314 (rank : 68)	NC score	0.026699 (rank : 114)
Query Neighborhood Hits	114	Target Neighborhood Hits	58	Shared Neighborhood Hits	4
SwissProt Accessions	P31321	Gene names	PRKAR1B
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

SDPR_MOUSE
θ value	0.62314 (rank : 69)	NC score	0.018518 (rank : 122)
Query Neighborhood Hits	114	Target Neighborhood Hits	485	Shared Neighborhood Hits	7
SwissProt Accessions	Q63918, Q3V1P6, Q78EC3, Q8CBT4	Gene names	Sdpr, Sdr
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein).

JHD2B_HUMAN
θ value	1.06291 (rank : 70)	NC score	0.028548 (rank : 113)
Query Neighborhood Hits	114	Target Neighborhood Hits	171	Shared Neighborhood Hits	12
SwissProt Accessions	Q7LBC6, Q9BVH6, Q9BW93, Q9BZ52, Q9NYF4, Q9UPS0	Gene names	JMJD1B, C5orf7, JHDM2B, KIAA1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA).

ZIMP7_MOUSE
θ value	1.06291 (rank : 71)	NC score	0.014321 (rank : 128)
Query Neighborhood Hits	114	Target Neighborhood Hits	566	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

K1219_HUMAN
θ value	1.38821 (rank : 72)	NC score	0.030614 (rank : 111)
Query Neighborhood Hits	114	Target Neighborhood Hits	85	Shared Neighborhood Hits	6
SwissProt Accessions	Q86X10, Q5TG31, Q8N3D1, Q8WWC0, Q9H3X8, Q9UJR1, Q9ULK1, Q9Y3G9	Gene names	KIAA1219
Domain Architecture	No domain graphic available
Description	Protein KIAA1219.

DNMBP_MOUSE
θ value	1.81305 (rank : 73)	NC score	0.044878 (rank : 108)
Query Neighborhood Hits	114	Target Neighborhood Hits	435	Shared Neighborhood Hits	20
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

IWS1_HUMAN
θ value	1.81305 (rank : 74)	NC score	0.021182 (rank : 119)
Query Neighborhood Hits	114	Target Neighborhood Hits	1241	Shared Neighborhood Hits	30
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

NECD_HUMAN
θ value	1.81305 (rank : 75)	NC score	0.009853 (rank : 138)
Query Neighborhood Hits	114	Target Neighborhood Hits	82	Shared Neighborhood Hits	4
SwissProt Accessions	Q99608	Gene names	NDN
Domain Architecture
Description	Necdin.

ABL1_MOUSE
θ value	2.36792 (rank : 76)	NC score	0.004823 (rank : 146)
Query Neighborhood Hits	114	Target Neighborhood Hits	1178	Shared Neighborhood Hits	21
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

HAIR_HUMAN
θ value	2.36792 (rank : 77)	NC score	0.040775 (rank : 110)
Query Neighborhood Hits	114	Target Neighborhood Hits	172	Shared Neighborhood Hits	7
SwissProt Accessions	O43593, Q96H33, Q9NPE1	Gene names	HR
Domain Architecture
Description	Protein hairless.

PELP1_MOUSE
θ value	2.36792 (rank : 78)	NC score	0.023217 (rank : 116)
Query Neighborhood Hits	114	Target Neighborhood Hits	709	Shared Neighborhood Hits	16
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

ZSCA1_HUMAN
θ value	2.36792 (rank : 79)	NC score	-0.000613 (rank : 154)
Query Neighborhood Hits	114	Target Neighborhood Hits	724	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NBB4, Q6WLH8, Q86WS8	Gene names	ZSCAN1
Domain Architecture	No domain graphic available
Description	Zinc finger and SCAN domain-containing protein 1.

BSN_MOUSE
θ value	3.0926 (rank : 80)	NC score	0.022591 (rank : 117)
Query Neighborhood Hits	114	Target Neighborhood Hits	2057	Shared Neighborhood Hits	38
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

DDX54_HUMAN
θ value	3.0926 (rank : 81)	NC score	0.003165 (rank : 149)
Query Neighborhood Hits	114	Target Neighborhood Hits	170	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).

HMCS1_MOUSE
θ value	3.0926 (rank : 82)	NC score	0.012118 (rank : 130)
Query Neighborhood Hits	114	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q8JZK9, Q3UXI4	Gene names	Hmgcs1
Domain Architecture	No domain graphic available
Description	Hydroxymethylglutaryl-CoA synthase, cytoplasmic (EC 2.3.3.10) (HMG-CoA synthase) (3-hydroxy-3-methylglutaryl coenzyme A synthase).

KAP1_MOUSE
θ value	3.0926 (rank : 83)	NC score	0.020206 (rank : 121)
Query Neighborhood Hits	114	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	P12849	Gene names	Prkar1b
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KI21B_MOUSE
θ value	3.0926 (rank : 84)	NC score	0.001222 (rank : 152)
Query Neighborhood Hits	114	Target Neighborhood Hits	997	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QXL1, P97424	Gene names	Kif21b, Kif6
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B (Kinesin-like protein KIF6).

OSBL3_MOUSE
θ value	3.0926 (rank : 85)	NC score	0.010242 (rank : 135)
Query Neighborhood Hits	114	Target Neighborhood Hits	86	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DBS9	Gene names	Osbpl3, Orp3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

ZN750_HUMAN
θ value	3.0926 (rank : 86)	NC score	0.015045 (rank : 126)
Query Neighborhood Hits	114	Target Neighborhood Hits	183	Shared Neighborhood Hits	6
SwissProt Accessions	Q32MQ0, Q9H899	Gene names	ZNF750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

DOT1L_HUMAN
θ value	4.03905 (rank : 87)	NC score	0.018197 (rank : 124)
Query Neighborhood Hits	114	Target Neighborhood Hits	660	Shared Neighborhood Hits	14
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

PMS2_HUMAN
θ value	4.03905 (rank : 88)	NC score	0.020343 (rank : 120)
Query Neighborhood Hits	114	Target Neighborhood Hits	131	Shared Neighborhood Hits	8
SwissProt Accessions	P54278	Gene names	PMS2, PMSL2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

SHD_HUMAN
θ value	4.03905 (rank : 89)	NC score	0.022387 (rank : 118)
Query Neighborhood Hits	114	Target Neighborhood Hits	204	Shared Neighborhood Hits	8
SwissProt Accessions	Q96IW2, Q96NC2	Gene names	SHD
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein D.

SRRM2_HUMAN
θ value	4.03905 (rank : 90)	NC score	0.028987 (rank : 112)
Query Neighborhood Hits	114	Target Neighborhood Hits	1296	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SRRM2_MOUSE
θ value	4.03905 (rank : 91)	NC score	0.026428 (rank : 115)
Query Neighborhood Hits	114	Target Neighborhood Hits	1470	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

FILA_HUMAN
θ value	5.27518 (rank : 92)	NC score	0.010394 (rank : 133)
Query Neighborhood Hits	114	Target Neighborhood Hits	685	Shared Neighborhood Hits	19
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

HSN2_MOUSE
θ value	5.27518 (rank : 93)	NC score	0.015001 (rank : 127)
Query Neighborhood Hits	114	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q6IFS6	Gene names	Hsn2
Domain Architecture	No domain graphic available
Description	Protein HSN2 precursor.

SI1L3_HUMAN
θ value	5.27518 (rank : 94)	NC score	0.009934 (rank : 137)
Query Neighborhood Hits	114	Target Neighborhood Hits	305	Shared Neighborhood Hits	12
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

TGON2_HUMAN
θ value	5.27518 (rank : 95)	NC score	0.007348 (rank : 140)
Query Neighborhood Hits	114	Target Neighborhood Hits	1037	Shared Neighborhood Hits	24
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

WDR22_HUMAN
θ value	5.27518 (rank : 96)	NC score	0.005963 (rank : 143)
Query Neighborhood Hits	114	Target Neighborhood Hits	328	Shared Neighborhood Hits	6
SwissProt Accessions	Q96JK2, O60559, Q8N3V3, Q8N3V5	Gene names	WDR22, BCRG2, KIAA1824
Domain Architecture
Description	WD repeat protein 22 (Breakpoint cluster region protein 2) (BCRP2).

DPOLZ_HUMAN
θ value	6.88961 (rank : 97)	NC score	0.010382 (rank : 134)
Query Neighborhood Hits	114	Target Neighborhood Hits	200	Shared Neighborhood Hits	12
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

MAST4_HUMAN
θ value	6.88961 (rank : 98)	NC score	-0.000940 (rank : 155)
Query Neighborhood Hits	114	Target Neighborhood Hits	1804	Shared Neighborhood Hits	29
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

TREF1_MOUSE
θ value	6.88961 (rank : 99)	NC score	0.013880 (rank : 129)
Query Neighborhood Hits	114	Target Neighborhood Hits	682	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BXJ2, Q6PCQ4, Q80X25, Q810H8, Q8BY31	Gene names	Trerf1
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132).

ZO2_HUMAN
θ value	6.88961 (rank : 100)	NC score	0.007174 (rank : 141)
Query Neighborhood Hits	114	Target Neighborhood Hits	289	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

AKAP2_HUMAN
θ value	8.99809 (rank : 101)	NC score	0.005684 (rank : 144)
Query Neighborhood Hits	114	Target Neighborhood Hits	507	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

ANKS1_HUMAN
θ value	8.99809 (rank : 102)	NC score	-0.000490 (rank : 153)
Query Neighborhood Hits	114	Target Neighborhood Hits	438	Shared Neighborhood Hits	8
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

B4GT1_HUMAN
θ value	8.99809 (rank : 103)	NC score	0.004926 (rank : 145)
Query Neighborhood Hits	114	Target Neighborhood Hits	168	Shared Neighborhood Hits	3
SwissProt Accessions	P15291, Q12909, Q12910, Q12911, Q14456, Q14509, Q14523	Gene names	B4GALT1, GGTB2
Domain Architecture
Description	Beta-1,4-galactosyltransferase 1 (EC 2.4.1.-) (Beta-1,4-GalTase 1) (Beta4Gal-T1) (b4Gal-T1) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 1) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 1) [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4- galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl- glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

CAC1G_HUMAN
θ value	8.99809 (rank : 104)	NC score	0.008163 (rank : 139)
Query Neighborhood Hits	114	Target Neighborhood Hits	587	Shared Neighborhood Hits	18
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

CTR9_HUMAN
θ value	8.99809 (rank : 105)	NC score	0.010037 (rank : 136)
Query Neighborhood Hits	114	Target Neighborhood Hits	383	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PD62, Q15015	Gene names	CTR9, KIAA0155, SH2BP1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1).

GPTC8_HUMAN
θ value	8.99809 (rank : 106)	NC score	0.017021 (rank : 125)
Query Neighborhood Hits	114	Target Neighborhood Hits	366	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

IKBL_HUMAN
θ value	8.99809 (rank : 107)	NC score	0.006415 (rank : 142)
Query Neighborhood Hits	114	Target Neighborhood Hits	168	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UBC1, Q14625, Q9UBX4	Gene names	NFKBIL1, IKBL
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

K1718_HUMAN
θ value	8.99809 (rank : 108)	NC score	0.003540 (rank : 148)
Query Neighborhood Hits	114	Target Neighborhood Hits	114	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZMT4, Q6MZL8, Q9C0E5	Gene names	KIAA1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

MKRN3_MOUSE
θ value	8.99809 (rank : 109)	NC score	0.004637 (rank : 147)
Query Neighborhood Hits	114	Target Neighborhood Hits	137	Shared Neighborhood Hits	2
SwissProt Accessions	Q60764, Q7TQE4	Gene names	Mkrn3, Zfp127, Znf127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127).

PCLO_MOUSE
θ value	8.99809 (rank : 110)	NC score	0.018264 (rank : 123)
Query Neighborhood Hits	114	Target Neighborhood Hits	2275	Shared Neighborhood Hits	43
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

RP3A_MOUSE
θ value	8.99809 (rank : 111)	NC score	0.001465 (rank : 151)
Query Neighborhood Hits	114	Target Neighborhood Hits	510	Shared Neighborhood Hits	11
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SEMG2_HUMAN
θ value	8.99809 (rank : 112)	NC score	0.011888 (rank : 131)
Query Neighborhood Hits	114	Target Neighborhood Hits	251	Shared Neighborhood Hits	9
SwissProt Accessions	Q02383, Q6X2M6	Gene names	SEMG2
Domain Architecture
Description	Semenogelin-2 precursor (Semenogelin II) (SGII).

SEN34_MOUSE
θ value	8.99809 (rank : 113)	NC score	0.010413 (rank : 132)
Query Neighborhood Hits	114	Target Neighborhood Hits	158	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BMZ5, Q58EU2, Q99LV6, Q9CYW1	Gene names	Tsen34, Leng5, Sen34
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen34 (EC 3.1.27.9) (tRNA-intron endonuclease Sen34) (Leukocyte receptor cluster member 5 homolog).

USH2A_MOUSE
θ value	8.99809 (rank : 114)	NC score	-0.001234 (rank : 156)
Query Neighborhood Hits	114	Target Neighborhood Hits	626	Shared Neighborhood Hits	4
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

ATCAY_HUMAN
θ value	θ > 10 (rank : 115)	NC score	0.060630 (rank : 77)
Query Neighborhood Hits	114	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q86WG3, Q8NAQ2, Q8TAQ3, Q96HC6, Q96JF5	Gene names	ATCAY, KIAA1872
Domain Architecture
Description	Caytaxin (Ataxia Cayman type protein) (BNIP-H).

ATCAY_MOUSE
θ value	θ > 10 (rank : 116)	NC score	0.061413 (rank : 75)
Query Neighborhood Hits	114	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BHE3, Q3TR94	Gene names	Atcay
Domain Architecture
Description	Caytaxin.

BNIP2_HUMAN
θ value	θ > 10 (rank : 117)	NC score	0.064367 (rank : 73)
Query Neighborhood Hits	114	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q12982	Gene names	BNIP2, NIP2
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 2.

BNIP2_MOUSE
θ value	θ > 10 (rank : 118)	NC score	0.064227 (rank : 74)
Query Neighborhood Hits	114	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	O54940	Gene names	Bnip2, Nip2l
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 2.

BNIPL_HUMAN
θ value	θ > 10 (rank : 119)	NC score	0.059199 (rank : 79)
Query Neighborhood Hits	114	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z465, Q6DK43, Q8TCY7, Q8WYG2	Gene names	BNIPL
Domain Architecture	No domain graphic available
Description	Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein.

BNIPL_MOUSE
θ value	θ > 10 (rank : 120)	NC score	0.059445 (rank : 78)
Query Neighborhood Hits	114	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q99JU7, Q923E3	Gene names	Bnipl
Domain Architecture	No domain graphic available
Description	Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein.

CENA1_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.051804 (rank : 100)
Query Neighborhood Hits	114	Target Neighborhood Hits	87	Shared Neighborhood Hits	5
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

CENA2_HUMAN
θ value	θ > 10 (rank : 122)	NC score	0.056380 (rank : 83)
Query Neighborhood Hits	114	Target Neighborhood Hits	83	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

CENB1_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.069126 (rank : 71)
Query Neighborhood Hits	114	Target Neighborhood Hits	383	Shared Neighborhood Hits	13
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

CENB2_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.073815 (rank : 68)
Query Neighborhood Hits	114	Target Neighborhood Hits	425	Shared Neighborhood Hits	13
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

CENB5_HUMAN
θ value	θ > 10 (rank : 125)	NC score	0.068330 (rank : 72)
Query Neighborhood Hits	114	Target Neighborhood Hits	395	Shared Neighborhood Hits	11
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

CIP4_HUMAN
θ value	θ > 10 (rank : 126)	NC score	0.056815 (rank : 82)
Query Neighborhood Hits	114	Target Neighborhood Hits	374	Shared Neighborhood Hits	9
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

DDEF1_MOUSE
θ value	θ > 10 (rank : 127)	NC score	0.050656 (rank : 104)
Query Neighborhood Hits	114	Target Neighborhood Hits	592	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

DDEF2_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.055193 (rank : 86)
Query Neighborhood Hits	114	Target Neighborhood Hits	599	Shared Neighborhood Hits	22
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
θ value	θ > 10 (rank : 129)	NC score	0.054490 (rank : 89)
Query Neighborhood Hits	114	Target Neighborhood Hits	625	Shared Neighborhood Hits	23
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDFL1_HUMAN
θ value	θ > 10 (rank : 130)	NC score	0.052179 (rank : 99)
Query Neighborhood Hits	114	Target Neighborhood Hits	353	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

FA13A_HUMAN
θ value	θ > 10 (rank : 131)	NC score	0.074671 (rank : 67)
Query Neighborhood Hits	114	Target Neighborhood Hits	102	Shared Neighborhood Hits	3
SwissProt Accessions	O94988, Q8NBA3	Gene names	FAM13A1, KIAA0914
Domain Architecture	No domain graphic available
Description	Protein FAM13A1.

FA13A_MOUSE
θ value	θ > 10 (rank : 132)	NC score	0.075633 (rank : 66)
Query Neighborhood Hits	114	Target Neighborhood Hits	83	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BGI4, Q8BZ91	Gene names	Fam13a1, Precm1
Domain Architecture	No domain graphic available
Description	Protein FAM13A1 (Precm1 protein).

FA13C_HUMAN
θ value	θ > 10 (rank : 133)	NC score	0.058898 (rank : 80)
Query Neighborhood Hits	114	Target Neighborhood Hits	94	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NE31, Q99787	Gene names	FAM13C1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

FA13C_MOUSE
θ value	θ > 10 (rank : 134)	NC score	0.057807 (rank : 81)
Query Neighborhood Hits	114	Target Neighborhood Hits	79	Shared Neighborhood Hits	5
SwissProt Accessions	Q9DBR2	Gene names	Fam13c1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

GRAP_HUMAN
θ value	θ > 10 (rank : 135)	NC score	0.056050 (rank : 84)
Query Neighborhood Hits	114	Target Neighborhood Hits	307	Shared Neighborhood Hits	17
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

GRAP_MOUSE
θ value	θ > 10 (rank : 136)	NC score	0.052767 (rank : 97)
Query Neighborhood Hits	114	Target Neighborhood Hits	309	Shared Neighborhood Hits	17
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

GRB2_HUMAN
θ value	θ > 10 (rank : 137)	NC score	0.053153 (rank : 92)
Query Neighborhood Hits	114	Target Neighborhood Hits	310	Shared Neighborhood Hits	17
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
θ value	θ > 10 (rank : 138)	NC score	0.053145 (rank : 93)
Query Neighborhood Hits	114	Target Neighborhood Hits	312	Shared Neighborhood Hits	17
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

GRP3_HUMAN
θ value	θ > 10 (rank : 139)	NC score	0.072947 (rank : 70)
Query Neighborhood Hits	114	Target Neighborhood Hits	131	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IV61, O94931	Gene names	RASGRP3, GRP3, KIAA0846
Domain Architecture
Description	RAS guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1).

NCF4_MOUSE
θ value	θ > 10 (rank : 140)	NC score	0.050334 (rank : 105)
Query Neighborhood Hits	114	Target Neighborhood Hits	177	Shared Neighborhood Hits	10
SwissProt Accessions	P97369	Gene names	Ncf4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

NCK2_HUMAN
θ value	θ > 10 (rank : 141)	NC score	0.061328 (rank : 76)
Query Neighborhood Hits	114	Target Neighborhood Hits	310	Shared Neighborhood Hits	20
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

P85B_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.078580 (rank : 65)
Query Neighborhood Hits	114	Target Neighborhood Hits	543	Shared Neighborhood Hits	28
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

P85B_MOUSE
θ value	θ > 10 (rank : 143)	NC score	0.052983 (rank : 95)
Query Neighborhood Hits	114	Target Neighborhood Hits	519	Shared Neighborhood Hits	23
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

PCTL_HUMAN
θ value	θ > 10 (rank : 144)	NC score	0.082208 (rank : 64)
Query Neighborhood Hits	114	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y365, O60532	Gene names	STARD10, SDCCAG28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28) (Antigen NY-CO-28).

PCTL_MOUSE
θ value	θ > 10 (rank : 145)	NC score	0.083138 (rank : 63)
Query Neighborhood Hits	114	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JMD3	Gene names	Stard10, Pctpl, Sdccag28, Sdccagg28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28 homolog).

PDZD8_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.052734 (rank : 98)
Query Neighborhood Hits	114	Target Neighborhood Hits	185	Shared Neighborhood Hits	12
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

PKHA1_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.054483 (rank : 90)
Query Neighborhood Hits	114	Target Neighborhood Hits	127	Shared Neighborhood Hits	11
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

SMAP1_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.053100 (rank : 94)
Query Neighborhood Hits	114	Target Neighborhood Hits	98	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SMAP1_MOUSE
θ value	θ > 10 (rank : 149)	NC score	0.052958 (rank : 96)
Query Neighborhood Hits	114	Target Neighborhood Hits	120	Shared Neighborhood Hits	5
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SMP1L_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.054714 (rank : 87)
Query Neighborhood Hits	114	Target Neighborhood Hits	74	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

SMP1L_MOUSE
θ value	θ > 10 (rank : 151)	NC score	0.054565 (rank : 88)
Query Neighborhood Hits	114	Target Neighborhood Hits	70	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

SRBS1_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.051314 (rank : 102)
Query Neighborhood Hits	114	Target Neighborhood Hits	396	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SRBS1_MOUSE
θ value	θ > 10 (rank : 153)	NC score	0.050197 (rank : 106)
Query Neighborhood Hits	114	Target Neighborhood Hits	409	Shared Neighborhood Hits	25
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

VAV3_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.051324 (rank : 101)
Query Neighborhood Hits	114	Target Neighborhood Hits	398	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

VAV3_MOUSE
θ value	θ > 10 (rank : 155)	NC score	0.050802 (rank : 103)
Query Neighborhood Hits	114	Target Neighborhood Hits	404	Shared Neighborhood Hits	21
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

VINEX_MOUSE
θ value	θ > 10 (rank : 156)	NC score	0.053232 (rank : 91)
Query Neighborhood Hits	114	Target Neighborhood Hits	286	Shared Neighborhood Hits	17
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

Hits sorted by NC score

RHG06_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	114	Target Neighborhood Hits	114	Shared Neighborhood Hits	114
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RHG06_MOUSE
NC score	0.994230 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	114	Target Neighborhood Hits	105	Shared Neighborhood Hits	73
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

3BP1_MOUSE
NC score	0.809581 (rank : 3)	θ value	1.80466e-16 (rank : 13)
Query Neighborhood Hits	114	Target Neighborhood Hits	238	Shared Neighborhood Hits	66
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

RHG01_HUMAN
NC score	0.799530 (rank : 4)	θ value	2.69047e-20 (rank : 4)
Query Neighborhood Hits	114	Target Neighborhood Hits	75	Shared Neighborhood Hits	62
SwissProt Accessions	Q07960	Gene names	ARHGAP1, CDC42GAP, RHOGAP1
Domain Architecture
Description	Rho-GTPase-activating protein 1 (GTPase-activating protein rhoOGAP) (Rho-related small GTPase protein activator) (CDC42 GTPase-activating protein) (p50-RhoGAP).

GMIP_MOUSE
NC score	0.790769 (rank : 5)	θ value	3.07829e-16 (rank : 14)
Query Neighborhood Hits	114	Target Neighborhood Hits	202	Shared Neighborhood Hits	63
SwissProt Accessions	Q6PGG2, Q6P9S3	Gene names	Gmip
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

3BP1_HUMAN
NC score	0.789867 (rank : 6)	θ value	7.32683e-18 (rank : 10)
Query Neighborhood Hits	114	Target Neighborhood Hits	376	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

RHG09_HUMAN
NC score	0.789746 (rank : 7)	θ value	3.89403e-11 (rank : 50)
Query Neighborhood Hits	114	Target Neighborhood Hits	186	Shared Neighborhood Hits	62
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

RHG12_HUMAN
NC score	0.785582 (rank : 8)	θ value	5.60996e-18 (rank : 9)
Query Neighborhood Hits	114	Target Neighborhood Hits	190	Shared Neighborhood Hits	61
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RHG12_MOUSE
NC score	0.783693 (rank : 9)	θ value	1.24977e-17 (rank : 11)
Query Neighborhood Hits	114	Target Neighborhood Hits	204	Shared Neighborhood Hits	64
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

GMIP_HUMAN
NC score	0.779891 (rank : 10)	θ value	1.42992e-13 (rank : 33)
Query Neighborhood Hits	114	Target Neighborhood Hits	225	Shared Neighborhood Hits	64
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

RHG18_HUMAN
NC score	0.778129 (rank : 11)	θ value	7.09661e-13 (rank : 42)
Query Neighborhood Hits	114	Target Neighborhood Hits	90	Shared Neighborhood Hits	61
SwissProt Accessions	Q8N392, Q58EZ3, Q6P679, Q6PJD7, Q96S64	Gene names	ARHGAP18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18 (MacGAP).

RGAP1_HUMAN
NC score	0.777791 (rank : 12)	θ value	1.86753e-13 (rank : 35)
Query Neighborhood Hits	114	Target Neighborhood Hits	189	Shared Neighborhood Hits	61
SwissProt Accessions	Q9H0H5, Q6PJ26, Q9NWN2, Q9P250, Q9P2W2	Gene names	RACGAP1, KIAA1478, MGCRACGAP
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RHG18_MOUSE
NC score	0.775499 (rank : 13)	θ value	3.52202e-12 (rank : 46)
Query Neighborhood Hits	114	Target Neighborhood Hits	110	Shared Neighborhood Hits	62
SwissProt Accessions	Q8K0Q5, Q8BP03, Q8R196	Gene names	Arhgap18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18.

RHG08_MOUSE
NC score	0.772893 (rank : 14)	θ value	2.60593e-15 (rank : 24)
Query Neighborhood Hits	114	Target Neighborhood Hits	73	Shared Neighborhood Hits	62
SwissProt Accessions	Q9CXP4, Q99JY7	Gene names	Arhgap8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RGAP1_MOUSE
NC score	0.768998 (rank : 15)	θ value	2.69671e-12 (rank : 45)
Query Neighborhood Hits	114	Target Neighborhood Hits	185	Shared Neighborhood Hits	62
SwissProt Accessions	Q9WVM1, Q3THR5, Q3TI41, Q3TM81	Gene names	Racgap1, Mgcracgap
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RHG08_HUMAN
NC score	0.768869 (rank : 16)	θ value	1.16975e-15 (rank : 22)
Query Neighborhood Hits	114	Target Neighborhood Hits	88	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NSG0, O75983, O95695, Q96RW1, Q96RW2, Q9HA49, Q9HC46, Q9NVX8, Q9NXL1, Q9UH20	Gene names	ARHGAP8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

GRLF1_HUMAN
NC score	0.746671 (rank : 17)	θ value	1.33837e-11 (rank : 49)
Query Neighborhood Hits	114	Target Neighborhood Hits	167	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

CHIO_MOUSE
NC score	0.746619 (rank : 18)	θ value	4.02038e-16 (rank : 17)
Query Neighborhood Hits	114	Target Neighborhood Hits	130	Shared Neighborhood Hits	61
SwissProt Accessions	Q80XD1, Q9D9W2, Q9ER57	Gene names	Chn2, Arhgap3, Bch
Domain Architecture	No domain graphic available
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

TCGAP_MOUSE
NC score	0.741170 (rank : 19)	θ value	4.44505e-15 (rank : 28)
Query Neighborhood Hits	114	Target Neighborhood Hits	409	Shared Neighborhood Hits	70
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

RHG07_MOUSE
NC score	0.736290 (rank : 20)	θ value	1.63225e-17 (rank : 12)
Query Neighborhood Hits	114	Target Neighborhood Hits	103	Shared Neighborhood Hits	62
SwissProt Accessions	Q9R0Z9, Q8R541	Gene names	Dlc1, Arhgap7, Stard12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein homolog) (Dlc-1) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

RHG07_HUMAN
NC score	0.733934 (rank : 21)	θ value	1.92812e-18 (rank : 8)
Query Neighborhood Hits	114	Target Neighborhood Hits	108	Shared Neighborhood Hits	64
SwissProt Accessions	Q96QB1, O14868, O43199, Q9C0E0	Gene names	DLC1, ARHGAP7, KIAA1723, STARD12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein) (Dlc-1) (HP protein) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

TAGAP_HUMAN
NC score	0.733744 (rank : 22)	θ value	5.43371e-13 (rank : 41)
Query Neighborhood Hits	114	Target Neighborhood Hits	82	Shared Neighborhood Hits	60
SwissProt Accessions	Q8N103, Q2NKM8, Q8NI40, Q96KZ2, Q96QA2	Gene names	TAGAP, TAGAP1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

TAGAP_MOUSE
NC score	0.731686 (rank : 23)	θ value	1.02475e-11 (rank : 47)
Query Neighborhood Hits	114	Target Neighborhood Hits	83	Shared Neighborhood Hits	61
SwissProt Accessions	Q8K2L9, Q920D6	Gene names	Tagap, Tagap1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

CHIN_MOUSE
NC score	0.723863 (rank : 24)	θ value	5.07402e-19 (rank : 6)
Query Neighborhood Hits	114	Target Neighborhood Hits	229	Shared Neighborhood Hits	64
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

RHG25_MOUSE
NC score	0.723168 (rank : 25)	θ value	3.07829e-16 (rank : 15)
Query Neighborhood Hits	114	Target Neighborhood Hits	492	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

CHIN_HUMAN
NC score	0.722793 (rank : 26)	θ value	7.82807e-20 (rank : 5)
Query Neighborhood Hits	114	Target Neighborhood Hits	227	Shared Neighborhood Hits	63
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

RHG04_HUMAN
NC score	0.720618 (rank : 27)	θ value	9.90251e-15 (rank : 29)
Query Neighborhood Hits	114	Target Neighborhood Hits	307	Shared Neighborhood Hits	66
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

SRGP2_HUMAN
NC score	0.719414 (rank : 28)	θ value	2.06002e-20 (rank : 3)
Query Neighborhood Hits	114	Target Neighborhood Hits	331	Shared Neighborhood Hits	67
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

OPHN1_MOUSE
NC score	0.718867 (rank : 29)	θ value	8.67504e-11 (rank : 53)
Query Neighborhood Hits	114	Target Neighborhood Hits	174	Shared Neighborhood Hits	63
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

OPHN1_HUMAN
NC score	0.717573 (rank : 30)	θ value	4.30538e-10 (rank : 55)
Query Neighborhood Hits	114	Target Neighborhood Hits	161	Shared Neighborhood Hits	64
SwissProt Accessions	O60890, Q5JQ81, Q8WX47	Gene names	OPHN1
Domain Architecture
Description	Oligophrenin 1.

RBP1_MOUSE
NC score	0.715677 (rank : 31)	θ value	3.40345e-15 (rank : 25)
Query Neighborhood Hits	114	Target Neighborhood Hits	493	Shared Neighborhood Hits	61
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

CHIO_HUMAN
NC score	0.715408 (rank : 32)	θ value	5.25075e-16 (rank : 19)
Query Neighborhood Hits	114	Target Neighborhood Hits	220	Shared Neighborhood Hits	62
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

SRGP2_MOUSE
NC score	0.710916 (rank : 33)	θ value	5.07402e-19 (rank : 7)
Query Neighborhood Hits	114	Target Neighborhood Hits	324	Shared Neighborhood Hits	65
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

ABR_HUMAN
NC score	0.710661 (rank : 34)	θ value	4.44505e-15 (rank : 27)
Query Neighborhood Hits	114	Target Neighborhood Hits	166	Shared Neighborhood Hits	65
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

RHG05_MOUSE
NC score	0.710540 (rank : 35)	θ value	1.133e-10 (rank : 54)
Query Neighborhood Hits	114	Target Neighborhood Hits	165	Shared Neighborhood Hits	62
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

STAR8_MOUSE
NC score	0.701657 (rank : 36)	θ value	3.07829e-16 (rank : 16)
Query Neighborhood Hits	114	Target Neighborhood Hits	101	Shared Neighborhood Hits	60
SwissProt Accessions	Q8K031, Q3UZC7, Q6A0A8, Q6P5E0, Q8R3X8	Gene names	Stard8, Kiaa0189
Domain Architecture	No domain graphic available
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

RHG25_HUMAN
NC score	0.699747 (rank : 37)	θ value	4.02038e-16 (rank : 18)
Query Neighborhood Hits	114	Target Neighborhood Hits	550	Shared Neighborhood Hits	64
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RHG05_HUMAN
NC score	0.697146 (rank : 38)	θ value	2.13673e-09 (rank : 56)
Query Neighborhood Hits	114	Target Neighborhood Hits	158	Shared Neighborhood Hits	62
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

BCR_HUMAN
NC score	0.693040 (rank : 39)	θ value	2.20605e-14 (rank : 31)
Query Neighborhood Hits	114	Target Neighborhood Hits	204	Shared Neighborhood Hits	66
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

FNBP2_HUMAN
NC score	0.692808 (rank : 40)	θ value	2.60593e-15 (rank : 23)
Query Neighborhood Hits	114	Target Neighborhood Hits	432	Shared Neighborhood Hits	65
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

RBP1_HUMAN
NC score	0.692204 (rank : 41)	θ value	1.86753e-13 (rank : 34)
Query Neighborhood Hits	114	Target Neighborhood Hits	521	Shared Neighborhood Hits	61
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

STAR8_HUMAN
NC score	0.691475 (rank : 42)	θ value	3.40345e-15 (rank : 26)
Query Neighborhood Hits	114	Target Neighborhood Hits	216	Shared Neighborhood Hits	65
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

RHG26_HUMAN
NC score	0.690301 (rank : 43)	θ value	9.26847e-13 (rank : 43)
Query Neighborhood Hits	114	Target Neighborhood Hits	281	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

SRGP1_HUMAN
NC score	0.688818 (rank : 44)	θ value	3.18553e-13 (rank : 37)
Query Neighborhood Hits	114	Target Neighborhood Hits	390	Shared Neighborhood Hits	64
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

STA13_HUMAN
NC score	0.688082 (rank : 45)	θ value	5.43371e-13 (rank : 40)
Query Neighborhood Hits	114	Target Neighborhood Hits	89	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y3M8, Q5HYH1, Q5TAE3, Q6UN61, Q86TP6, Q86WQ3, Q86XT1	Gene names	STARD13, DLC2, GT650
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13) (46H23.2) (Deleted in liver cancer protein 2) (Rho GTPase-activating protein).

STA13_MOUSE
NC score	0.683730 (rank : 46)	θ value	3.76295e-14 (rank : 32)
Query Neighborhood Hits	114	Target Neighborhood Hits	89	Shared Neighborhood Hits	59
SwissProt Accessions	Q923Q2, Q8K369	Gene names	Stard13
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13).

TCGAP_HUMAN
NC score	0.659217 (rank : 47)	θ value	9.90251e-15 (rank : 30)
Query Neighborhood Hits	114	Target Neighborhood Hits	872	Shared Neighborhood Hits	77
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

CE005_HUMAN
NC score	0.645732 (rank : 48)	θ value	4.16044e-13 (rank : 38)
Query Neighborhood Hits	114	Target Neighborhood Hits	213	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

CE005_MOUSE
NC score	0.643785 (rank : 49)	θ value	2.43908e-13 (rank : 36)
Query Neighborhood Hits	114	Target Neighborhood Hits	238	Shared Neighborhood Hits	62
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

CEND2_HUMAN
NC score	0.624449 (rank : 50)	θ value	1.33837e-11 (rank : 48)
Query Neighborhood Hits	114	Target Neighborhood Hits	166	Shared Neighborhood Hits	60
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

CEND3_MOUSE
NC score	0.598379 (rank : 51)	θ value	4.16044e-13 (rank : 39)
Query Neighborhood Hits	114	Target Neighborhood Hits	228	Shared Neighborhood Hits	62
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

CEND3_HUMAN
NC score	0.587288 (rank : 52)	θ value	1.58096e-12 (rank : 44)
Query Neighborhood Hits	114	Target Neighborhood Hits	275	Shared Neighborhood Hits	65
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

K1688_MOUSE
NC score	0.555386 (rank : 53)	θ value	8.40245e-06 (rank : 58)
Query Neighborhood Hits	114	Target Neighborhood Hits	188	Shared Neighborhood Hits	62
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

K1688_HUMAN
NC score	0.543386 (rank : 54)	θ value	8.40245e-06 (rank : 57)
Query Neighborhood Hits	114	Target Neighborhood Hits	217	Shared Neighborhood Hits	64
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

CEND1_MOUSE
NC score	0.532979 (rank : 55)	θ value	6.64225e-11 (rank : 52)
Query Neighborhood Hits	114	Target Neighborhood Hits	260	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

CEND1_HUMAN
NC score	0.514064 (rank : 56)	θ value	6.64225e-11 (rank : 51)
Query Neighborhood Hits	114	Target Neighborhood Hits	284	Shared Neighborhood Hits	57
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

MYO9B_MOUSE
NC score	0.413929 (rank : 57)	θ value	8.95645e-16 (rank : 21)
Query Neighborhood Hits	114	Target Neighborhood Hits	311	Shared Neighborhood Hits	70
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

MYO9B_HUMAN
NC score	0.408678 (rank : 58)	θ value	6.85773e-16 (rank : 20)
Query Neighborhood Hits	114	Target Neighborhood Hits	641	Shared Neighborhood Hits	72
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

P85A_HUMAN
NC score	0.350449 (rank : 59)	θ value	0.000602161 (rank : 60)
Query Neighborhood Hits	114	Target Neighborhood Hits	479	Shared Neighborhood Hits	61
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

OCRL_HUMAN
NC score	0.344616 (rank : 60)	θ value	8.40245e-06 (rank : 59)
Query Neighborhood Hits	114	Target Neighborhood Hits	77	Shared Neighborhood Hits	51
SwissProt Accessions	Q01968, O60800, Q15684, Q15774, Q5JQF1, Q5JQF2, Q9UJG5, Q9UMA5	Gene names	OCRL, INPP5F, OCRL1
Domain Architecture
Description	Inositol polyphosphate 5-phosphatase OCRL-1 (EC 3.1.3.36) (Lowe oculocerebrorenal syndrome protein).

I5P2_HUMAN
NC score	0.336942 (rank : 61)	θ value	0.0113563 (rank : 61)
Query Neighborhood Hits	114	Target Neighborhood Hits	86	Shared Neighborhood Hits	52
SwissProt Accessions	P32019, Q5VSG9, Q5VSH0, Q5VSH1, Q658Q5, Q6P6D4, Q6PD53, Q86YE1	Gene names	INPP5B
Domain Architecture	No domain graphic available
Description	Type II inositol-1,4,5-trisphosphate 5-phosphatase precursor (EC 3.1.3.36) (Phosphoinositide 5-phosphatase) (5PTase) (75 kDa inositol polyphosphate-5-phosphatase).

P85A_MOUSE
NC score	0.335745 (rank : 62)	θ value	0.125558 (rank : 64)
Query Neighborhood Hits	114	Target Neighborhood Hits	435	Shared Neighborhood Hits	61
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

PCTL_MOUSE
NC score	0.083138 (rank : 63)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	114	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JMD3	Gene names	Stard10, Pctpl, Sdccag28, Sdccagg28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28 homolog).

PCTL_HUMAN
NC score	0.082208 (rank : 64)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	114	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y365, O60532	Gene names	STARD10, SDCCAG28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28) (Antigen NY-CO-28).

P85B_HUMAN
NC score	0.078580 (rank : 65)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	114	Target Neighborhood Hits	543	Shared Neighborhood Hits	28
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

FA13A_MOUSE
NC score	0.075633 (rank : 66)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	114	Target Neighborhood Hits	83	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BGI4, Q8BZ91	Gene names	Fam13a1, Precm1
Domain Architecture	No domain graphic available
Description	Protein FAM13A1 (Precm1 protein).

FA13A_HUMAN
NC score	0.074671 (rank : 67)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	114	Target Neighborhood Hits	102	Shared Neighborhood Hits	3
SwissProt Accessions	O94988, Q8NBA3	Gene names	FAM13A1, KIAA0914
Domain Architecture	No domain graphic available
Description	Protein FAM13A1.

CENB2_HUMAN
NC score	0.073815 (rank : 68)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	114	Target Neighborhood Hits	425	Shared Neighborhood Hits	13
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

DYDC2_HUMAN
NC score	0.073722 (rank : 69)	θ value	0.365318 (rank : 67)
Query Neighborhood Hits	114	Target Neighborhood Hits	55	Shared Neighborhood Hits	3
SwissProt Accessions	Q96IM9, Q5QP07, Q5QP11	Gene names	DYDC2
Domain Architecture	No domain graphic available
Description	DPY30 domain-containing protein 2.

GRP3_HUMAN
NC score	0.072947 (rank : 70)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	114	Target Neighborhood Hits	131	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IV61, O94931	Gene names	RASGRP3, GRP3, KIAA0846
Domain Architecture
Description	RAS guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1).

CENB1_HUMAN
NC score	0.069126 (rank : 71)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	114	Target Neighborhood Hits	383	Shared Neighborhood Hits	13
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

CENB5_HUMAN
NC score	0.068330 (rank : 72)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	114	Target Neighborhood Hits	395	Shared Neighborhood Hits	11
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

BNIP2_HUMAN
NC score	0.064367 (rank : 73)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	114	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q12982	Gene names	BNIP2, NIP2
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 2.

BNIP2_MOUSE
NC score	0.064227 (rank : 74)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	114	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	O54940	Gene names	Bnip2, Nip2l
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 2.

ATCAY_MOUSE
NC score	0.061413 (rank : 75)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	114	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BHE3, Q3TR94	Gene names	Atcay
Domain Architecture
Description	Caytaxin.

NCK2_HUMAN
NC score	0.061328 (rank : 76)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	114	Target Neighborhood Hits	310	Shared Neighborhood Hits	20
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

ATCAY_HUMAN
NC score	0.060630 (rank : 77)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	114	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q86WG3, Q8NAQ2, Q8TAQ3, Q96HC6, Q96JF5	Gene names	ATCAY, KIAA1872
Domain Architecture
Description	Caytaxin (Ataxia Cayman type protein) (BNIP-H).

BNIPL_MOUSE
NC score	0.059445 (rank : 78)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	114	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q99JU7, Q923E3	Gene names	Bnipl
Domain Architecture	No domain graphic available
Description	Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein.

BNIPL_HUMAN
NC score	0.059199 (rank : 79)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	114	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z465, Q6DK43, Q8TCY7, Q8WYG2	Gene names	BNIPL
Domain Architecture	No domain graphic available
Description	Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein.

FA13C_HUMAN
NC score	0.058898 (rank : 80)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	114	Target Neighborhood Hits	94	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NE31, Q99787	Gene names	FAM13C1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

FA13C_MOUSE
NC score	0.057807 (rank : 81)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	114	Target Neighborhood Hits	79	Shared Neighborhood Hits	5
SwissProt Accessions	Q9DBR2	Gene names	Fam13c1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

CIP4_HUMAN
NC score	0.056815 (rank : 82)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	114	Target Neighborhood Hits	374	Shared Neighborhood Hits	9
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

CENA2_HUMAN
NC score	0.056380 (rank : 83)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	114	Target Neighborhood Hits	83	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

GRAP_HUMAN
NC score	0.056050 (rank : 84)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	114	Target Neighborhood Hits	307	Shared Neighborhood Hits	17
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

EFS_HUMAN
NC score	0.055497 (rank : 85)	θ value	0.0330416 (rank : 63)
Query Neighborhood Hits	114	Target Neighborhood Hits	348	Shared Neighborhood Hits	16
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

DDEF2_HUMAN
NC score	0.055193 (rank : 86)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	114	Target Neighborhood Hits	599	Shared Neighborhood Hits	22
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

SMP1L_HUMAN
NC score	0.054714 (rank : 87)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	114	Target Neighborhood Hits	74	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

SMP1L_MOUSE
NC score	0.054565 (rank : 88)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	114	Target Neighborhood Hits	70	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

DDEF2_MOUSE
NC score	0.054490 (rank : 89)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	114	Target Neighborhood Hits	625	Shared Neighborhood Hits	23
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

PKHA1_HUMAN
NC score	0.054483 (rank : 90)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	114	Target Neighborhood Hits	127	Shared Neighborhood Hits	11
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

VINEX_MOUSE
NC score	0.053232 (rank : 91)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	114	Target Neighborhood Hits	286	Shared Neighborhood Hits	17
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

GRB2_HUMAN
NC score	0.053153 (rank : 92)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	114	Target Neighborhood Hits	310	Shared Neighborhood Hits	17
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
NC score	0.053145 (rank : 93)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	114	Target Neighborhood Hits	312	Shared Neighborhood Hits	17
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

SMAP1_HUMAN
NC score	0.053100 (rank : 94)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	114	Target Neighborhood Hits	98	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

P85B_MOUSE
NC score	0.052983 (rank : 95)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	114	Target Neighborhood Hits	519	Shared Neighborhood Hits	23
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

SMAP1_MOUSE
NC score	0.052958 (rank : 96)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	114	Target Neighborhood Hits	120	Shared Neighborhood Hits	5
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

GRAP_MOUSE
NC score	0.052767 (rank : 97)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	114	Target Neighborhood Hits	309	Shared Neighborhood Hits	17
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

PDZD8_HUMAN
NC score	0.052734 (rank : 98)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	114	Target Neighborhood Hits	185	Shared Neighborhood Hits	12
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

DDFL1_HUMAN
NC score	0.052179 (rank : 99)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	114	Target Neighborhood Hits	353	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

CENA1_HUMAN
NC score	0.051804 (rank : 100)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	114	Target Neighborhood Hits	87	Shared Neighborhood Hits	5
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

VAV3_HUMAN
NC score	0.051324 (rank : 101)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	114	Target Neighborhood Hits	398	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

SRBS1_HUMAN
NC score	0.051314 (rank : 102)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	114	Target Neighborhood Hits	396	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

VAV3_MOUSE
NC score	0.050802 (rank : 103)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	114	Target Neighborhood Hits	404	Shared Neighborhood Hits	21
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

DDEF1_MOUSE
NC score	0.050656 (rank : 104)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	114	Target Neighborhood Hits	592	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

NCF4_MOUSE
NC score	0.050334 (rank : 105)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	114	Target Neighborhood Hits	177	Shared Neighborhood Hits	10
SwissProt Accessions	P97369	Gene names	Ncf4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

SRBS1_MOUSE
NC score	0.050197 (rank : 106)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	114	Target Neighborhood Hits	409	Shared Neighborhood Hits	25
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

HAIR_MOUSE
NC score	0.046623 (rank : 107)	θ value	0.0148317 (rank : 62)
Query Neighborhood Hits	114	Target Neighborhood Hits	97	Shared Neighborhood Hits	6
SwissProt Accessions	Q61645, Q80Y47	Gene names	Hr
Domain Architecture
Description	Protein hairless.

DNMBP_MOUSE
NC score	0.044878 (rank : 108)	θ value	1.81305 (rank : 73)
Query Neighborhood Hits	114	Target Neighborhood Hits	435	Shared Neighborhood Hits	20
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

DCR1A_MOUSE
NC score	0.042726 (rank : 109)	θ value	0.21417 (rank : 66)
Query Neighborhood Hits	114	Target Neighborhood Hits	59	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JIC3, Q571H5, Q6GQR6	Gene names	Dclre1a, Kiaa0086, Snm1, Snm1a
Domain Architecture	No domain graphic available
Description	DNA cross-link repair 1A protein.

HAIR_HUMAN
NC score	0.040775 (rank : 110)	θ value	2.36792 (rank : 77)
Query Neighborhood Hits	114	Target Neighborhood Hits	172	Shared Neighborhood Hits	7
SwissProt Accessions	O43593, Q96H33, Q9NPE1	Gene names	HR
Domain Architecture
Description	Protein hairless.

K1219_HUMAN
NC score	0.030614 (rank : 111)	θ value	1.38821 (rank : 72)
Query Neighborhood Hits	114	Target Neighborhood Hits	85	Shared Neighborhood Hits	6
SwissProt Accessions	Q86X10, Q5TG31, Q8N3D1, Q8WWC0, Q9H3X8, Q9UJR1, Q9ULK1, Q9Y3G9	Gene names	KIAA1219
Domain Architecture	No domain graphic available
Description	Protein KIAA1219.

SRRM2_HUMAN
NC score	0.028987 (rank : 112)	θ value	4.03905 (rank : 90)
Query Neighborhood Hits	114	Target Neighborhood Hits	1296	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

JHD2B_HUMAN
NC score	0.028548 (rank : 113)	θ value	1.06291 (rank : 70)
Query Neighborhood Hits	114	Target Neighborhood Hits	171	Shared Neighborhood Hits	12
SwissProt Accessions	Q7LBC6, Q9BVH6, Q9BW93, Q9BZ52, Q9NYF4, Q9UPS0	Gene names	JMJD1B, C5orf7, JHDM2B, KIAA1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA).

KAP1_HUMAN
NC score	0.026699 (rank : 114)	θ value	0.62314 (rank : 68)
Query Neighborhood Hits	114	Target Neighborhood Hits	58	Shared Neighborhood Hits	4
SwissProt Accessions	P31321	Gene names	PRKAR1B
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

SRRM2_MOUSE
NC score	0.026428 (rank : 115)	θ value	4.03905 (rank : 91)
Query Neighborhood Hits	114	Target Neighborhood Hits	1470	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

PELP1_MOUSE
NC score	0.023217 (rank : 116)	θ value	2.36792 (rank : 78)
Query Neighborhood Hits	114	Target Neighborhood Hits	709	Shared Neighborhood Hits	16
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

BSN_MOUSE
NC score	0.022591 (rank : 117)	θ value	3.0926 (rank : 80)
Query Neighborhood Hits	114	Target Neighborhood Hits	2057	Shared Neighborhood Hits	38
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

SHD_HUMAN
NC score	0.022387 (rank : 118)	θ value	4.03905 (rank : 89)
Query Neighborhood Hits	114	Target Neighborhood Hits	204	Shared Neighborhood Hits	8
SwissProt Accessions	Q96IW2, Q96NC2	Gene names	SHD
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein D.

IWS1_HUMAN
NC score	0.021182 (rank : 119)	θ value	1.81305 (rank : 74)
Query Neighborhood Hits	114	Target Neighborhood Hits	1241	Shared Neighborhood Hits	30
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

PMS2_HUMAN
NC score	0.020343 (rank : 120)	θ value	4.03905 (rank : 88)
Query Neighborhood Hits	114	Target Neighborhood Hits	131	Shared Neighborhood Hits	8
SwissProt Accessions	P54278	Gene names	PMS2, PMSL2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

KAP1_MOUSE
NC score	0.020206 (rank : 121)	θ value	3.0926 (rank : 83)
Query Neighborhood Hits	114	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	P12849	Gene names	Prkar1b
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

SDPR_MOUSE
NC score	0.018518 (rank : 122)	θ value	0.62314 (rank : 69)
Query Neighborhood Hits	114	Target Neighborhood Hits	485	Shared Neighborhood Hits	7
SwissProt Accessions	Q63918, Q3V1P6, Q78EC3, Q8CBT4	Gene names	Sdpr, Sdr
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein).

PCLO_MOUSE
NC score	0.018264 (rank : 123)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	114	Target Neighborhood Hits	2275	Shared Neighborhood Hits	43
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

DOT1L_HUMAN
NC score	0.018197 (rank : 124)	θ value	4.03905 (rank : 87)
Query Neighborhood Hits	114	Target Neighborhood Hits	660	Shared Neighborhood Hits	14
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

GPTC8_HUMAN
NC score	0.017021 (rank : 125)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	114	Target Neighborhood Hits	366	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

ZN750_HUMAN
NC score	0.015045 (rank : 126)	θ value	3.0926 (rank : 86)
Query Neighborhood Hits	114	Target Neighborhood Hits	183	Shared Neighborhood Hits	6
SwissProt Accessions	Q32MQ0, Q9H899	Gene names	ZNF750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

HSN2_MOUSE
NC score	0.015001 (rank : 127)	θ value	5.27518 (rank : 93)
Query Neighborhood Hits	114	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q6IFS6	Gene names	Hsn2
Domain Architecture	No domain graphic available
Description	Protein HSN2 precursor.

ZIMP7_MOUSE
NC score	0.014321 (rank : 128)	θ value	1.06291 (rank : 71)
Query Neighborhood Hits	114	Target Neighborhood Hits	566	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

TREF1_MOUSE
NC score	0.013880 (rank : 129)	θ value	6.88961 (rank : 99)
Query Neighborhood Hits	114	Target Neighborhood Hits	682	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BXJ2, Q6PCQ4, Q80X25, Q810H8, Q8BY31	Gene names	Trerf1
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132).

HMCS1_MOUSE
NC score	0.012118 (rank : 130)	θ value	3.0926 (rank : 82)
Query Neighborhood Hits	114	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q8JZK9, Q3UXI4	Gene names	Hmgcs1
Domain Architecture	No domain graphic available
Description	Hydroxymethylglutaryl-CoA synthase, cytoplasmic (EC 2.3.3.10) (HMG-CoA synthase) (3-hydroxy-3-methylglutaryl coenzyme A synthase).

SEMG2_HUMAN
NC score	0.011888 (rank : 131)	θ value	8.99809 (rank : 112)
Query Neighborhood Hits	114	Target Neighborhood Hits	251	Shared Neighborhood Hits	9
SwissProt Accessions	Q02383, Q6X2M6	Gene names	SEMG2
Domain Architecture
Description	Semenogelin-2 precursor (Semenogelin II) (SGII).

SEN34_MOUSE
NC score	0.010413 (rank : 132)	θ value	8.99809 (rank : 113)
Query Neighborhood Hits	114	Target Neighborhood Hits	158	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BMZ5, Q58EU2, Q99LV6, Q9CYW1	Gene names	Tsen34, Leng5, Sen34
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen34 (EC 3.1.27.9) (tRNA-intron endonuclease Sen34) (Leukocyte receptor cluster member 5 homolog).

FILA_HUMAN
NC score	0.010394 (rank : 133)	θ value	5.27518 (rank : 92)
Query Neighborhood Hits	114	Target Neighborhood Hits	685	Shared Neighborhood Hits	19
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

DPOLZ_HUMAN
NC score	0.010382 (rank : 134)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	114	Target Neighborhood Hits	200	Shared Neighborhood Hits	12
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

OSBL3_MOUSE
NC score	0.010242 (rank : 135)	θ value	3.0926 (rank : 85)
Query Neighborhood Hits	114	Target Neighborhood Hits	86	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DBS9	Gene names	Osbpl3, Orp3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

CTR9_HUMAN
NC score	0.010037 (rank : 136)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	114	Target Neighborhood Hits	383	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PD62, Q15015	Gene names	CTR9, KIAA0155, SH2BP1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1).

SI1L3_HUMAN
NC score	0.009934 (rank : 137)	θ value	5.27518 (rank : 94)
Query Neighborhood Hits	114	Target Neighborhood Hits	305	Shared Neighborhood Hits	12
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

NECD_HUMAN
NC score	0.009853 (rank : 138)	θ value	1.81305 (rank : 75)
Query Neighborhood Hits	114	Target Neighborhood Hits	82	Shared Neighborhood Hits	4
SwissProt Accessions	Q99608	Gene names	NDN
Domain Architecture
Description	Necdin.

CAC1G_HUMAN
NC score	0.008163 (rank : 139)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	114	Target Neighborhood Hits	587	Shared Neighborhood Hits	18
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

TGON2_HUMAN
NC score	0.007348 (rank : 140)	θ value	5.27518 (rank : 95)
Query Neighborhood Hits	114	Target Neighborhood Hits	1037	Shared Neighborhood Hits	24
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

ZO2_HUMAN
NC score	0.007174 (rank : 141)	θ value	6.88961 (rank : 100)
Query Neighborhood Hits	114	Target Neighborhood Hits	289	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

IKBL_HUMAN
NC score	0.006415 (rank : 142)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	114	Target Neighborhood Hits	168	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UBC1, Q14625, Q9UBX4	Gene names	NFKBIL1, IKBL
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

WDR22_HUMAN
NC score	0.005963 (rank : 143)	θ value	5.27518 (rank : 96)
Query Neighborhood Hits	114	Target Neighborhood Hits	328	Shared Neighborhood Hits	6
SwissProt Accessions	Q96JK2, O60559, Q8N3V3, Q8N3V5	Gene names	WDR22, BCRG2, KIAA1824
Domain Architecture
Description	WD repeat protein 22 (Breakpoint cluster region protein 2) (BCRP2).

AKAP2_HUMAN
NC score	0.005684 (rank : 144)	θ value	8.99809 (rank : 101)
Query Neighborhood Hits	114	Target Neighborhood Hits	507	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

B4GT1_HUMAN
NC score	0.004926 (rank : 145)	θ value	8.99809 (rank : 103)
Query Neighborhood Hits	114	Target Neighborhood Hits	168	Shared Neighborhood Hits	3
SwissProt Accessions	P15291, Q12909, Q12910, Q12911, Q14456, Q14509, Q14523	Gene names	B4GALT1, GGTB2
Domain Architecture
Description	Beta-1,4-galactosyltransferase 1 (EC 2.4.1.-) (Beta-1,4-GalTase 1) (Beta4Gal-T1) (b4Gal-T1) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 1) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 1) [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4- galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl- glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

ABL1_MOUSE
NC score	0.004823 (rank : 146)	θ value	2.36792 (rank : 76)
Query Neighborhood Hits	114	Target Neighborhood Hits	1178	Shared Neighborhood Hits	21
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

MKRN3_MOUSE
NC score	0.004637 (rank : 147)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	114	Target Neighborhood Hits	137	Shared Neighborhood Hits	2
SwissProt Accessions	Q60764, Q7TQE4	Gene names	Mkrn3, Zfp127, Znf127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127).

K1718_HUMAN
NC score	0.003540 (rank : 148)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	114	Target Neighborhood Hits	114	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZMT4, Q6MZL8, Q9C0E5	Gene names	KIAA1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

DDX54_HUMAN
NC score	0.003165 (rank : 149)	θ value	3.0926 (rank : 81)
Query Neighborhood Hits	114	Target Neighborhood Hits	170	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).

CD2L7_HUMAN
NC score	0.002109 (rank : 150)	θ value	0.21417 (rank : 65)
Query Neighborhood Hits	114	Target Neighborhood Hits	1275	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

RP3A_MOUSE
NC score	0.001465 (rank : 151)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	114	Target Neighborhood Hits	510	Shared Neighborhood Hits	11
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

KI21B_MOUSE
NC score	0.001222 (rank : 152)	θ value	3.0926 (rank : 84)
Query Neighborhood Hits	114	Target Neighborhood Hits	997	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QXL1, P97424	Gene names	Kif21b, Kif6
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B (Kinesin-like protein KIF6).

ANKS1_HUMAN
NC score	-0.000490 (rank : 153)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	114	Target Neighborhood Hits	438	Shared Neighborhood Hits	8
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

ZSCA1_HUMAN
NC score	-0.000613 (rank : 154)	θ value	2.36792 (rank : 79)
Query Neighborhood Hits	114	Target Neighborhood Hits	724	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NBB4, Q6WLH8, Q86WS8	Gene names	ZSCAN1
Domain Architecture	No domain graphic available
Description	Zinc finger and SCAN domain-containing protein 1.

MAST4_HUMAN
NC score	-0.000940 (rank : 155)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	114	Target Neighborhood Hits	1804	Shared Neighborhood Hits	29
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

USH2A_MOUSE
NC score	-0.001234 (rank : 156)	θ value	8.99809 (rank : 114)
Query Neighborhood Hits	114	Target Neighborhood Hits	626	Shared Neighborhood Hits	4
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).