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Network neighborhood for query Sequence : 3BP1_HUMAN

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3BP1_HUMAN
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

3BP1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	376	Target Neighborhood Hits	376	Shared Neighborhood Hits	376
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

3BP1_MOUSE
θ value	0 (rank : 2)	NC score	0.951607 (rank : 2)
Query Neighborhood Hits	376	Target Neighborhood Hits	238	Shared Neighborhood Hits	158
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

CHIN_HUMAN
θ value	6.84181e-24 (rank : 3)	NC score	0.719951 (rank : 27)
Query Neighborhood Hits	376	Target Neighborhood Hits	227	Shared Neighborhood Hits	65
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

ABR_HUMAN
θ value	1.5242e-23 (rank : 4)	NC score	0.717347 (rank : 30)
Query Neighborhood Hits	376	Target Neighborhood Hits	166	Shared Neighborhood Hits	70
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

CHIN_MOUSE
θ value	1.99067e-23 (rank : 5)	NC score	0.722877 (rank : 25)
Query Neighborhood Hits	376	Target Neighborhood Hits	229	Shared Neighborhood Hits	66
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

RHG04_HUMAN
θ value	7.56453e-23 (rank : 6)	NC score	0.722556 (rank : 26)
Query Neighborhood Hits	376	Target Neighborhood Hits	307	Shared Neighborhood Hits	81
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

CHIO_MOUSE
θ value	3.75424e-22 (rank : 7)	NC score	0.749590 (rank : 19)
Query Neighborhood Hits	376	Target Neighborhood Hits	130	Shared Neighborhood Hits	64
SwissProt Accessions	Q80XD1, Q9D9W2, Q9ER57	Gene names	Chn2, Arhgap3, Bch
Domain Architecture	No domain graphic available
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

TCGAP_HUMAN
θ value	4.9032e-22 (rank : 8)	NC score	0.703298 (rank : 36)
Query Neighborhood Hits	376	Target Neighborhood Hits	872	Shared Neighborhood Hits	179
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

BCR_HUMAN
θ value	8.36355e-22 (rank : 9)	NC score	0.704113 (rank : 33)
Query Neighborhood Hits	376	Target Neighborhood Hits	204	Shared Neighborhood Hits	85
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

CHIO_HUMAN
θ value	1.42661e-21 (rank : 10)	NC score	0.717738 (rank : 29)
Query Neighborhood Hits	376	Target Neighborhood Hits	220	Shared Neighborhood Hits	66
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

TCGAP_MOUSE
θ value	1.42661e-21 (rank : 11)	NC score	0.781580 (rank : 6)
Query Neighborhood Hits	376	Target Neighborhood Hits	409	Shared Neighborhood Hits	140
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

RHG01_HUMAN
θ value	1.86321e-21 (rank : 12)	NC score	0.779564 (rank : 9)
Query Neighborhood Hits	376	Target Neighborhood Hits	75	Shared Neighborhood Hits	62
SwissProt Accessions	Q07960	Gene names	ARHGAP1, CDC42GAP, RHOGAP1
Domain Architecture
Description	Rho-GTPase-activating protein 1 (GTPase-activating protein rhoOGAP) (Rho-related small GTPase protein activator) (CDC42 GTPase-activating protein) (p50-RhoGAP).

RHG12_MOUSE
θ value	3.17815e-21 (rank : 13)	NC score	0.781075 (rank : 8)
Query Neighborhood Hits	376	Target Neighborhood Hits	204	Shared Neighborhood Hits	68
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

TAGAP_HUMAN
θ value	5.42112e-21 (rank : 14)	NC score	0.745326 (rank : 20)
Query Neighborhood Hits	376	Target Neighborhood Hits	82	Shared Neighborhood Hits	61
SwissProt Accessions	Q8N103, Q2NKM8, Q8NI40, Q96KZ2, Q96QA2	Gene names	TAGAP, TAGAP1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

RHG12_HUMAN
θ value	7.0802e-21 (rank : 15)	NC score	0.781147 (rank : 7)
Query Neighborhood Hits	376	Target Neighborhood Hits	190	Shared Neighborhood Hits	66
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

MYO9B_MOUSE
θ value	1.2077e-20 (rank : 16)	NC score	0.424182 (rank : 58)
Query Neighborhood Hits	376	Target Neighborhood Hits	311	Shared Neighborhood Hits	88
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

MYO9B_HUMAN
θ value	1.5773e-20 (rank : 17)	NC score	0.426516 (rank : 57)
Query Neighborhood Hits	376	Target Neighborhood Hits	641	Shared Neighborhood Hits	136
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

RHG08_MOUSE
θ value	6.62687e-19 (rank : 18)	NC score	0.764716 (rank : 13)
Query Neighborhood Hits	376	Target Neighborhood Hits	73	Shared Neighborhood Hits	62
SwissProt Accessions	Q9CXP4, Q99JY7	Gene names	Arhgap8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

GRLF1_HUMAN
θ value	1.92812e-18 (rank : 19)	NC score	0.768116 (rank : 12)
Query Neighborhood Hits	376	Target Neighborhood Hits	167	Shared Neighborhood Hits	77
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

RHG06_MOUSE
θ value	1.92812e-18 (rank : 20)	NC score	0.789350 (rank : 5)
Query Neighborhood Hits	376	Target Neighborhood Hits	105	Shared Neighborhood Hits	66
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RHG08_HUMAN
θ value	2.5182e-18 (rank : 21)	NC score	0.763373 (rank : 14)
Query Neighborhood Hits	376	Target Neighborhood Hits	88	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NSG0, O75983, O95695, Q96RW1, Q96RW2, Q9HA49, Q9HC46, Q9NVX8, Q9NXL1, Q9UH20	Gene names	ARHGAP8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RHG06_HUMAN
θ value	7.32683e-18 (rank : 22)	NC score	0.789867 (rank : 4)
Query Neighborhood Hits	376	Target Neighborhood Hits	114	Shared Neighborhood Hits	69
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RHG09_HUMAN
θ value	9.56915e-18 (rank : 23)	NC score	0.802626 (rank : 3)
Query Neighborhood Hits	376	Target Neighborhood Hits	186	Shared Neighborhood Hits	77
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

SRGP2_HUMAN
θ value	9.56915e-18 (rank : 24)	NC score	0.707085 (rank : 32)
Query Neighborhood Hits	376	Target Neighborhood Hits	331	Shared Neighborhood Hits	88
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

TAGAP_MOUSE
θ value	1.24977e-17 (rank : 25)	NC score	0.743410 (rank : 21)
Query Neighborhood Hits	376	Target Neighborhood Hits	83	Shared Neighborhood Hits	62
SwissProt Accessions	Q8K2L9, Q920D6	Gene names	Tagap, Tagap1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

RHG25_HUMAN
θ value	1.63225e-17 (rank : 26)	NC score	0.695378 (rank : 39)
Query Neighborhood Hits	376	Target Neighborhood Hits	550	Shared Neighborhood Hits	90
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RHG26_HUMAN
θ value	1.63225e-17 (rank : 27)	NC score	0.703791 (rank : 34)
Query Neighborhood Hits	376	Target Neighborhood Hits	281	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

FNBP2_HUMAN
θ value	2.13179e-17 (rank : 28)	NC score	0.691799 (rank : 40)
Query Neighborhood Hits	376	Target Neighborhood Hits	432	Shared Neighborhood Hits	97
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

RHG25_MOUSE
θ value	2.13179e-17 (rank : 29)	NC score	0.716733 (rank : 31)
Query Neighborhood Hits	376	Target Neighborhood Hits	492	Shared Neighborhood Hits	97
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

SRGP2_MOUSE
θ value	2.13179e-17 (rank : 30)	NC score	0.700280 (rank : 37)
Query Neighborhood Hits	376	Target Neighborhood Hits	324	Shared Neighborhood Hits	88
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

RHG05_HUMAN
θ value	6.20254e-17 (rank : 31)	NC score	0.719086 (rank : 28)
Query Neighborhood Hits	376	Target Neighborhood Hits	158	Shared Neighborhood Hits	66
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

GMIP_MOUSE
θ value	1.058e-16 (rank : 32)	NC score	0.775944 (rank : 10)
Query Neighborhood Hits	376	Target Neighborhood Hits	202	Shared Neighborhood Hits	74
SwissProt Accessions	Q6PGG2, Q6P9S3	Gene names	Gmip
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

RHG07_MOUSE
θ value	1.058e-16 (rank : 33)	NC score	0.703525 (rank : 35)
Query Neighborhood Hits	376	Target Neighborhood Hits	103	Shared Neighborhood Hits	66
SwissProt Accessions	Q9R0Z9, Q8R541	Gene names	Dlc1, Arhgap7, Stard12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein homolog) (Dlc-1) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

RHG05_MOUSE
θ value	1.80466e-16 (rank : 34)	NC score	0.728366 (rank : 22)
Query Neighborhood Hits	376	Target Neighborhood Hits	165	Shared Neighborhood Hits	67
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

SRGP1_HUMAN
θ value	5.25075e-16 (rank : 35)	NC score	0.691157 (rank : 41)
Query Neighborhood Hits	376	Target Neighborhood Hits	390	Shared Neighborhood Hits	92
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

RHG07_HUMAN
θ value	6.85773e-16 (rank : 36)	NC score	0.698041 (rank : 38)
Query Neighborhood Hits	376	Target Neighborhood Hits	108	Shared Neighborhood Hits	65
SwissProt Accessions	Q96QB1, O14868, O43199, Q9C0E0	Gene names	DLC1, ARHGAP7, KIAA1723, STARD12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein) (Dlc-1) (HP protein) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

STA13_HUMAN
θ value	1.16975e-15 (rank : 37)	NC score	0.660177 (rank : 46)
Query Neighborhood Hits	376	Target Neighborhood Hits	89	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y3M8, Q5HYH1, Q5TAE3, Q6UN61, Q86TP6, Q86WQ3, Q86XT1	Gene names	STARD13, DLC2, GT650
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13) (46H23.2) (Deleted in liver cancer protein 2) (Rho GTPase-activating protein).

GMIP_HUMAN
θ value	2.60593e-15 (rank : 38)	NC score	0.773710 (rank : 11)
Query Neighborhood Hits	376	Target Neighborhood Hits	225	Shared Neighborhood Hits	80
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

STA13_MOUSE
θ value	3.40345e-15 (rank : 39)	NC score	0.652780 (rank : 47)
Query Neighborhood Hits	376	Target Neighborhood Hits	89	Shared Neighborhood Hits	59
SwissProt Accessions	Q923Q2, Q8K369	Gene names	Stard13
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13).

STAR8_HUMAN
θ value	1.68911e-14 (rank : 40)	NC score	0.665215 (rank : 45)
Query Neighborhood Hits	376	Target Neighborhood Hits	216	Shared Neighborhood Hits	84
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

STAR8_MOUSE
θ value	2.88119e-14 (rank : 41)	NC score	0.665856 (rank : 44)
Query Neighborhood Hits	376	Target Neighborhood Hits	101	Shared Neighborhood Hits	65
SwissProt Accessions	Q8K031, Q3UZC7, Q6A0A8, Q6P5E0, Q8R3X8	Gene names	Stard8, Kiaa0189
Domain Architecture	No domain graphic available
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

OPHN1_MOUSE
θ value	3.76295e-14 (rank : 42)	NC score	0.724331 (rank : 24)
Query Neighborhood Hits	376	Target Neighborhood Hits	174	Shared Neighborhood Hits	70
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

OPHN1_HUMAN
θ value	6.41864e-14 (rank : 43)	NC score	0.726629 (rank : 23)
Query Neighborhood Hits	376	Target Neighborhood Hits	161	Shared Neighborhood Hits	72
SwissProt Accessions	O60890, Q5JQ81, Q8WX47	Gene names	OPHN1
Domain Architecture
Description	Oligophrenin 1.

RHG18_HUMAN
θ value	6.41864e-14 (rank : 44)	NC score	0.753504 (rank : 17)
Query Neighborhood Hits	376	Target Neighborhood Hits	90	Shared Neighborhood Hits	62
SwissProt Accessions	Q8N392, Q58EZ3, Q6P679, Q6PJD7, Q96S64	Gene names	ARHGAP18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18 (MacGAP).

RHG18_MOUSE
θ value	1.09485e-13 (rank : 45)	NC score	0.754501 (rank : 16)
Query Neighborhood Hits	376	Target Neighborhood Hits	110	Shared Neighborhood Hits	63
SwissProt Accessions	Q8K0Q5, Q8BP03, Q8R196	Gene names	Arhgap18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18.

CEND2_HUMAN
θ value	7.09661e-13 (rank : 46)	NC score	0.593536 (rank : 48)
Query Neighborhood Hits	376	Target Neighborhood Hits	166	Shared Neighborhood Hits	66
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

RGAP1_HUMAN
θ value	9.26847e-13 (rank : 47)	NC score	0.756206 (rank : 15)
Query Neighborhood Hits	376	Target Neighborhood Hits	189	Shared Neighborhood Hits	70
SwissProt Accessions	Q9H0H5, Q6PJ26, Q9NWN2, Q9P250, Q9P2W2	Gene names	RACGAP1, KIAA1478, MGCRACGAP
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RGAP1_MOUSE
θ value	1.58096e-12 (rank : 48)	NC score	0.751045 (rank : 18)
Query Neighborhood Hits	376	Target Neighborhood Hits	185	Shared Neighborhood Hits	69
SwissProt Accessions	Q9WVM1, Q3THR5, Q3TI41, Q3TM81	Gene names	Racgap1, Mgcracgap
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RBP1_MOUSE
θ value	4.59992e-12 (rank : 49)	NC score	0.688653 (rank : 42)
Query Neighborhood Hits	376	Target Neighborhood Hits	493	Shared Neighborhood Hits	84
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

CEND3_MOUSE
θ value	1.33837e-11 (rank : 50)	NC score	0.567702 (rank : 52)
Query Neighborhood Hits	376	Target Neighborhood Hits	228	Shared Neighborhood Hits	92
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

RBP1_HUMAN
θ value	3.89403e-11 (rank : 51)	NC score	0.668470 (rank : 43)
Query Neighborhood Hits	376	Target Neighborhood Hits	521	Shared Neighborhood Hits	85
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

CEND3_HUMAN
θ value	1.47974e-10 (rank : 52)	NC score	0.557397 (rank : 54)
Query Neighborhood Hits	376	Target Neighborhood Hits	275	Shared Neighborhood Hits	101
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

K1688_HUMAN
θ value	2.36244e-08 (rank : 53)	NC score	0.557693 (rank : 53)
Query Neighborhood Hits	376	Target Neighborhood Hits	217	Shared Neighborhood Hits	75
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

K1688_MOUSE
θ value	4.0297e-08 (rank : 54)	NC score	0.569561 (rank : 51)
Query Neighborhood Hits	376	Target Neighborhood Hits	188	Shared Neighborhood Hits	77
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

NFH_MOUSE
θ value	5.26297e-08 (rank : 55)	NC score	0.096015 (rank : 165)
Query Neighborhood Hits	376	Target Neighborhood Hits	2247	Shared Neighborhood Hits	197
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

MUC1_HUMAN
θ value	8.97725e-08 (rank : 56)	NC score	0.111005 (rank : 129)
Query Neighborhood Hits	376	Target Neighborhood Hits	975	Shared Neighborhood Hits	127
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

CE005_HUMAN
θ value	9.92553e-07 (rank : 57)	NC score	0.588653 (rank : 49)
Query Neighborhood Hits	376	Target Neighborhood Hits	213	Shared Neighborhood Hits	69
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

P85A_MOUSE
θ value	1.29631e-06 (rank : 58)	NC score	0.372535 (rank : 60)
Query Neighborhood Hits	376	Target Neighborhood Hits	435	Shared Neighborhood Hits	84
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

CE005_MOUSE
θ value	2.21117e-06 (rank : 59)	NC score	0.585466 (rank : 50)
Query Neighborhood Hits	376	Target Neighborhood Hits	238	Shared Neighborhood Hits	70
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

CEND1_MOUSE
θ value	2.88788e-06 (rank : 60)	NC score	0.487107 (rank : 55)
Query Neighborhood Hits	376	Target Neighborhood Hits	260	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

RGS3_MOUSE
θ value	2.88788e-06 (rank : 61)	NC score	0.117976 (rank : 116)
Query Neighborhood Hits	376	Target Neighborhood Hits	1621	Shared Neighborhood Hits	162
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

OCRL_HUMAN
θ value	3.77169e-06 (rank : 62)	NC score	0.362415 (rank : 62)
Query Neighborhood Hits	376	Target Neighborhood Hits	77	Shared Neighborhood Hits	55
SwissProt Accessions	Q01968, O60800, Q15684, Q15774, Q5JQF1, Q5JQF2, Q9UJG5, Q9UMA5	Gene names	OCRL, INPP5F, OCRL1
Domain Architecture
Description	Inositol polyphosphate 5-phosphatase OCRL-1 (EC 3.1.3.36) (Lowe oculocerebrorenal syndrome protein).

I5P2_HUMAN
θ value	4.92598e-06 (rank : 63)	NC score	0.370565 (rank : 61)
Query Neighborhood Hits	376	Target Neighborhood Hits	86	Shared Neighborhood Hits	56
SwissProt Accessions	P32019, Q5VSG9, Q5VSH0, Q5VSH1, Q658Q5, Q6P6D4, Q6PD53, Q86YE1	Gene names	INPP5B
Domain Architecture	No domain graphic available
Description	Type II inositol-1,4,5-trisphosphate 5-phosphatase precursor (EC 3.1.3.36) (Phosphoinositide 5-phosphatase) (5PTase) (75 kDa inositol polyphosphate-5-phosphatase).

CEND1_HUMAN
θ value	1.43324e-05 (rank : 64)	NC score	0.466239 (rank : 56)
Query Neighborhood Hits	376	Target Neighborhood Hits	284	Shared Neighborhood Hits	65
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

OGFR_HUMAN
θ value	1.43324e-05 (rank : 65)	NC score	0.121677 (rank : 113)
Query Neighborhood Hits	376	Target Neighborhood Hits	1582	Shared Neighborhood Hits	159
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

MDC1_HUMAN
θ value	1.87187e-05 (rank : 66)	NC score	0.150330 (rank : 78)
Query Neighborhood Hits	376	Target Neighborhood Hits	1446	Shared Neighborhood Hits	165
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

P85A_HUMAN
θ value	3.19293e-05 (rank : 67)	NC score	0.373968 (rank : 59)
Query Neighborhood Hits	376	Target Neighborhood Hits	479	Shared Neighborhood Hits	82
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

SH3G1_HUMAN
θ value	9.29e-05 (rank : 68)	NC score	0.113680 (rank : 125)
Query Neighborhood Hits	376	Target Neighborhood Hits	307	Shared Neighborhood Hits	33
SwissProt Accessions	Q99961, Q99668	Gene names	SH3GL1, CNSA1, SH3D2B
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL).

PRRT3_HUMAN
θ value	0.000270298 (rank : 69)	NC score	0.116895 (rank : 118)
Query Neighborhood Hits	376	Target Neighborhood Hits	998	Shared Neighborhood Hits	121
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

SH3G2_MOUSE
θ value	0.000270298 (rank : 70)	NC score	0.113190 (rank : 126)
Query Neighborhood Hits	376	Target Neighborhood Hits	319	Shared Neighborhood Hits	35
SwissProt Accessions	Q62420	Gene names	Sh3gl2, Sh3d2a
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (SH3p4).

MAGE1_HUMAN
θ value	0.00035302 (rank : 71)	NC score	0.091658 (rank : 180)
Query Neighborhood Hits	376	Target Neighborhood Hits	1389	Shared Neighborhood Hits	168
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

NACAM_MOUSE
θ value	0.00035302 (rank : 72)	NC score	0.151810 (rank : 76)
Query Neighborhood Hits	376	Target Neighborhood Hits	1866	Shared Neighborhood Hits	217
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PDZD2_HUMAN
θ value	0.000461057 (rank : 73)	NC score	0.067085 (rank : 311)
Query Neighborhood Hits	376	Target Neighborhood Hits	772	Shared Neighborhood Hits	89
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

SON_HUMAN
θ value	0.000461057 (rank : 74)	NC score	0.102101 (rank : 150)
Query Neighborhood Hits	376	Target Neighborhood Hits	1568	Shared Neighborhood Hits	170
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

CABIN_HUMAN
θ value	0.000602161 (rank : 75)	NC score	0.138197 (rank : 86)
Query Neighborhood Hits	376	Target Neighborhood Hits	490	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

RGS3_HUMAN
θ value	0.000602161 (rank : 76)	NC score	0.092126 (rank : 178)
Query Neighborhood Hits	376	Target Neighborhood Hits	1375	Shared Neighborhood Hits	131
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

SH3G2_HUMAN
θ value	0.000602161 (rank : 77)	NC score	0.111114 (rank : 128)
Query Neighborhood Hits	376	Target Neighborhood Hits	324	Shared Neighborhood Hits	33
SwissProt Accessions	Q99962, Q9NQK5	Gene names	SH3GL2, CNSA2, SH3D2A
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (EEN-B1).

MDC1_MOUSE
θ value	0.000786445 (rank : 78)	NC score	0.140337 (rank : 81)
Query Neighborhood Hits	376	Target Neighborhood Hits	998	Shared Neighborhood Hits	138
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

CD248_HUMAN
θ value	0.00134147 (rank : 79)	NC score	0.051138 (rank : 501)
Query Neighborhood Hits	376	Target Neighborhood Hits	679	Shared Neighborhood Hits	76
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

SH3G1_MOUSE
θ value	0.00134147 (rank : 80)	NC score	0.110310 (rank : 131)
Query Neighborhood Hits	376	Target Neighborhood Hits	291	Shared Neighborhood Hits	33
SwissProt Accessions	Q62419	Gene names	Sh3gl1, Sh3d2b
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (SH3p8).

SHLB2_HUMAN
θ value	0.00134147 (rank : 81)	NC score	0.105433 (rank : 141)
Query Neighborhood Hits	376	Target Neighborhood Hits	86	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NR46, Q8WY61, Q96JH9	Gene names	SH3GLB2, KIAA1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

SHLB2_MOUSE
θ value	0.00175202 (rank : 82)	NC score	0.105175 (rank : 142)
Query Neighborhood Hits	376	Target Neighborhood Hits	88	Shared Neighborhood Hits	21
SwissProt Accessions	Q8R3V5, Q8K140, Q91ZI7	Gene names	Sh3glb2, Kiaa1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

SELPL_MOUSE
θ value	0.00228821 (rank : 83)	NC score	0.130818 (rank : 94)
Query Neighborhood Hits	376	Target Neighborhood Hits	588	Shared Neighborhood Hits	100
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

ZN409_HUMAN
θ value	0.00390308 (rank : 84)	NC score	0.042552 (rank : 531)
Query Neighborhood Hits	376	Target Neighborhood Hits	842	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UPU6	Gene names	ZNF409, KIAA1056
Domain Architecture	No domain graphic available
Description	Zinc finger protein 409.

BSN_MOUSE
θ value	0.00509761 (rank : 85)	NC score	0.134436 (rank : 87)
Query Neighborhood Hits	376	Target Neighborhood Hits	2057	Shared Neighborhood Hits	227
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

K1802_MOUSE
θ value	0.00665767 (rank : 86)	NC score	0.085576 (rank : 204)
Query Neighborhood Hits	376	Target Neighborhood Hits	1596	Shared Neighborhood Hits	163
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

NOTC2_MOUSE
θ value	0.00869519 (rank : 87)	NC score	0.022191 (rank : 612)
Query Neighborhood Hits	376	Target Neighborhood Hits	1069	Shared Neighborhood Hits	57
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

PCLO_HUMAN
θ value	0.00869519 (rank : 88)	NC score	0.138561 (rank : 85)
Query Neighborhood Hits	376	Target Neighborhood Hits	2046	Shared Neighborhood Hits	237
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PI5PA_HUMAN
θ value	0.00869519 (rank : 89)	NC score	0.130000 (rank : 96)
Query Neighborhood Hits	376	Target Neighborhood Hits	749	Shared Neighborhood Hits	135
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

CEL_HUMAN
θ value	0.0113563 (rank : 90)	NC score	0.052255 (rank : 482)
Query Neighborhood Hits	376	Target Neighborhood Hits	896	Shared Neighborhood Hits	102
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

CSKI1_MOUSE
θ value	0.0113563 (rank : 91)	NC score	0.072858 (rank : 270)
Query Neighborhood Hits	376	Target Neighborhood Hits	1031	Shared Neighborhood Hits	162
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

DMRTD_MOUSE
θ value	0.0113563 (rank : 92)	NC score	0.069107 (rank : 293)
Query Neighborhood Hits	376	Target Neighborhood Hits	72	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CGW9	Gene names	Dmrtc2, Dmrt7
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2 (Doublesex- and mab-3-related transcription factor 7).

CSF1_HUMAN
θ value	0.0148317 (rank : 93)	NC score	0.072533 (rank : 273)
Query Neighborhood Hits	376	Target Neighborhood Hits	258	Shared Neighborhood Hits	47
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

GAB1_HUMAN
θ value	0.0148317 (rank : 94)	NC score	0.063404 (rank : 341)
Query Neighborhood Hits	376	Target Neighborhood Hits	279	Shared Neighborhood Hits	46
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

K1543_HUMAN
θ value	0.0148317 (rank : 95)	NC score	0.091108 (rank : 181)
Query Neighborhood Hits	376	Target Neighborhood Hits	435	Shared Neighborhood Hits	77
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

SPR1B_MOUSE
θ value	0.0148317 (rank : 96)	NC score	0.062532 (rank : 350)
Query Neighborhood Hits	376	Target Neighborhood Hits	395	Shared Neighborhood Hits	57
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

AAK1_HUMAN
θ value	0.0193708 (rank : 97)	NC score	0.030610 (rank : 572)
Query Neighborhood Hits	376	Target Neighborhood Hits	1077	Shared Neighborhood Hits	99
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

EHMT2_MOUSE
θ value	0.0193708 (rank : 98)	NC score	0.036081 (rank : 548)
Query Neighborhood Hits	376	Target Neighborhood Hits	750	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

LTB1L_MOUSE
θ value	0.0193708 (rank : 99)	NC score	0.023645 (rank : 600)
Query Neighborhood Hits	376	Target Neighborhood Hits	514	Shared Neighborhood Hits	25
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	0.0193708 (rank : 100)	NC score	0.022991 (rank : 605)
Query Neighborhood Hits	376	Target Neighborhood Hits	479	Shared Neighborhood Hits	21
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

MBB1A_HUMAN
θ value	0.0193708 (rank : 101)	NC score	0.083886 (rank : 210)
Query Neighborhood Hits	376	Target Neighborhood Hits	665	Shared Neighborhood Hits	81
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

ANK2_HUMAN
θ value	0.0252991 (rank : 102)	NC score	0.046546 (rank : 520)
Query Neighborhood Hits	376	Target Neighborhood Hits	1615	Shared Neighborhood Hits	144
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ANR11_HUMAN
θ value	0.0252991 (rank : 103)	NC score	0.052774 (rank : 476)
Query Neighborhood Hits	376	Target Neighborhood Hits	1289	Shared Neighborhood Hits	110
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

LCP2_HUMAN
θ value	0.0252991 (rank : 104)	NC score	0.073557 (rank : 264)
Query Neighborhood Hits	376	Target Neighborhood Hits	531	Shared Neighborhood Hits	82
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

MLL3_MOUSE
θ value	0.0252991 (rank : 105)	NC score	0.078922 (rank : 228)
Query Neighborhood Hits	376	Target Neighborhood Hits	1399	Shared Neighborhood Hits	155
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

TXND2_HUMAN
θ value	0.0252991 (rank : 106)	NC score	0.077462 (rank : 239)
Query Neighborhood Hits	376	Target Neighborhood Hits	793	Shared Neighborhood Hits	81
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

DMRTD_HUMAN
θ value	0.0330416 (rank : 107)	NC score	0.067656 (rank : 307)
Query Neighborhood Hits	376	Target Neighborhood Hits	216	Shared Neighborhood Hits	34
SwissProt Accessions	Q8IXT2, Q8N6Q2, Q96M39, Q96SD4	Gene names	DMRTC2
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2.

HEMGN_MOUSE
θ value	0.0330416 (rank : 108)	NC score	0.056364 (rank : 424)
Query Neighborhood Hits	376	Target Neighborhood Hits	81	Shared Neighborhood Hits	16
SwissProt Accessions	Q9ERZ0, Q3TAE6, Q80YT2, Q8CF29	Gene names	Hemgn, Ndr
Domain Architecture	No domain graphic available
Description	Hemogen (Hemopoietic gene protein) (Negative differentiation regulator protein) (mNDR).

JADE2_MOUSE
θ value	0.0330416 (rank : 109)	NC score	0.053851 (rank : 459)
Query Neighborhood Hits	376	Target Neighborhood Hits	560	Shared Neighborhood Hits	87
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

PCLO_MOUSE
θ value	0.0330416 (rank : 110)	NC score	0.132817 (rank : 89)
Query Neighborhood Hits	376	Target Neighborhood Hits	2275	Shared Neighborhood Hits	235
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PSL1_HUMAN
θ value	0.0330416 (rank : 111)	NC score	0.059252 (rank : 391)
Query Neighborhood Hits	376	Target Neighborhood Hits	650	Shared Neighborhood Hits	74
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

ZN516_MOUSE
θ value	0.0330416 (rank : 112)	NC score	0.008429 (rank : 674)
Query Neighborhood Hits	376	Target Neighborhood Hits	1197	Shared Neighborhood Hits	83
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

ULK1_MOUSE
θ value	0.0431538 (rank : 113)	NC score	0.008720 (rank : 671)
Query Neighborhood Hits	376	Target Neighborhood Hits	1214	Shared Neighborhood Hits	80
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

ZN687_MOUSE
θ value	0.0563607 (rank : 114)	NC score	0.017847 (rank : 633)
Query Neighborhood Hits	376	Target Neighborhood Hits	913	Shared Neighborhood Hits	63
SwissProt Accessions	Q9D2D7, Q6PAP3, Q6ZPQ9	Gene names	Znf687, Kiaa1441, Zfp687
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

LPP_HUMAN
θ value	0.0736092 (rank : 115)	NC score	0.053660 (rank : 460)
Query Neighborhood Hits	376	Target Neighborhood Hits	775	Shared Neighborhood Hits	95
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

MAP1A_HUMAN
θ value	0.0736092 (rank : 116)	NC score	0.067571 (rank : 308)
Query Neighborhood Hits	376	Target Neighborhood Hits	1626	Shared Neighborhood Hits	149
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

PDLI7_HUMAN
θ value	0.0736092 (rank : 117)	NC score	0.033486 (rank : 559)
Query Neighborhood Hits	376	Target Neighborhood Hits	547	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

SRRM2_MOUSE
θ value	0.0736092 (rank : 118)	NC score	0.132681 (rank : 90)
Query Neighborhood Hits	376	Target Neighborhood Hits	1470	Shared Neighborhood Hits	184
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TARSH_HUMAN
θ value	0.0736092 (rank : 119)	NC score	0.124696 (rank : 107)
Query Neighborhood Hits	376	Target Neighborhood Hits	768	Shared Neighborhood Hits	116
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

CAC1G_HUMAN
θ value	0.0961366 (rank : 120)	NC score	0.034762 (rank : 552)
Query Neighborhood Hits	376	Target Neighborhood Hits	587	Shared Neighborhood Hits	70
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

DCC_MOUSE
θ value	0.0961366 (rank : 121)	NC score	0.021932 (rank : 615)
Query Neighborhood Hits	376	Target Neighborhood Hits	896	Shared Neighborhood Hits	69
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

GRIN1_HUMAN
θ value	0.0961366 (rank : 122)	NC score	0.081738 (rank : 221)
Query Neighborhood Hits	376	Target Neighborhood Hits	681	Shared Neighborhood Hits	97
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

NCOA6_HUMAN
θ value	0.0961366 (rank : 123)	NC score	0.101666 (rank : 151)
Query Neighborhood Hits	376	Target Neighborhood Hits	1202	Shared Neighborhood Hits	172
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

PTC2_HUMAN
θ value	0.0961366 (rank : 124)	NC score	0.028762 (rank : 581)
Query Neighborhood Hits	376	Target Neighborhood Hits	63	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y6C5, O95341, O95856, Q5QP87, Q6UX14	Gene names	PTCH2
Domain Architecture
Description	Protein patched homolog 2 (PTC2).

RTP3_MOUSE
θ value	0.0961366 (rank : 125)	NC score	0.083327 (rank : 213)
Query Neighborhood Hits	376	Target Neighborhood Hits	374	Shared Neighborhood Hits	66
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

CIC_HUMAN
θ value	0.125558 (rank : 126)	NC score	0.111138 (rank : 127)
Query Neighborhood Hits	376	Target Neighborhood Hits	992	Shared Neighborhood Hits	159
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

IASPP_MOUSE
θ value	0.125558 (rank : 127)	NC score	0.087928 (rank : 197)
Query Neighborhood Hits	376	Target Neighborhood Hits	1024	Shared Neighborhood Hits	122
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

SAPS1_HUMAN
θ value	0.125558 (rank : 128)	NC score	0.076652 (rank : 241)
Query Neighborhood Hits	376	Target Neighborhood Hits	704	Shared Neighborhood Hits	109
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

SH3G3_HUMAN
θ value	0.125558 (rank : 129)	NC score	0.100698 (rank : 152)
Query Neighborhood Hits	376	Target Neighborhood Hits	222	Shared Neighborhood Hits	27
SwissProt Accessions	Q99963, O43553, O43554	Gene names	SH3GL3, CNSA3, SH3D2C
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (EEN-B2).

DOCK4_HUMAN
θ value	0.163984 (rank : 130)	NC score	0.044874 (rank : 525)
Query Neighborhood Hits	376	Target Neighborhood Hits	237	Shared Neighborhood Hits	54
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

F100B_MOUSE
θ value	0.163984 (rank : 131)	NC score	0.045620 (rank : 522)
Query Neighborhood Hits	376	Target Neighborhood Hits	91	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BQH4, Q3UMH5	Gene names	Fam100b
Domain Architecture	No domain graphic available
Description	Protein FAM100B.

MYH4_MOUSE
θ value	0.163984 (rank : 132)	NC score	0.034356 (rank : 553)
Query Neighborhood Hits	376	Target Neighborhood Hits	1476	Shared Neighborhood Hits	65
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

ASPP1_MOUSE
θ value	0.21417 (rank : 133)	NC score	0.075849 (rank : 244)
Query Neighborhood Hits	376	Target Neighborhood Hits	1244	Shared Neighborhood Hits	138
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

CP007_MOUSE
θ value	0.21417 (rank : 134)	NC score	0.047173 (rank : 517)
Query Neighborhood Hits	376	Target Neighborhood Hits	231	Shared Neighborhood Hits	25
SwissProt Accessions	Q8C190, Q6PFD1	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf7 homolog (5-day ovary-specific transcript 1 protein).

K0240_MOUSE
θ value	0.21417 (rank : 135)	NC score	0.040204 (rank : 537)
Query Neighborhood Hits	376	Target Neighborhood Hits	211	Shared Neighborhood Hits	37
SwissProt Accessions	Q8CHH5	Gene names	Kiaa0240
Domain Architecture	No domain graphic available
Description	Protein KIAA0240.

MILK1_MOUSE
θ value	0.21417 (rank : 136)	NC score	0.095506 (rank : 166)
Query Neighborhood Hits	376	Target Neighborhood Hits	788	Shared Neighborhood Hits	139
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

SC24C_HUMAN
θ value	0.21417 (rank : 137)	NC score	0.072607 (rank : 272)
Query Neighborhood Hits	376	Target Neighborhood Hits	662	Shared Neighborhood Hits	94
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

SEPT9_HUMAN
θ value	0.21417 (rank : 138)	NC score	0.052439 (rank : 480)
Query Neighborhood Hits	376	Target Neighborhood Hits	706	Shared Neighborhood Hits	89
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

SPR1A_MOUSE
θ value	0.21417 (rank : 139)	NC score	0.060552 (rank : 365)
Query Neighborhood Hits	376	Target Neighborhood Hits	343	Shared Neighborhood Hits	50
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

SYNJ1_MOUSE
θ value	0.21417 (rank : 140)	NC score	0.124793 (rank : 105)
Query Neighborhood Hits	376	Target Neighborhood Hits	516	Shared Neighborhood Hits	149
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

BCL9_HUMAN
θ value	0.279714 (rank : 141)	NC score	0.090160 (rank : 189)
Query Neighborhood Hits	376	Target Neighborhood Hits	1008	Shared Neighborhood Hits	144
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

CAC1A_HUMAN
θ value	0.279714 (rank : 142)	NC score	0.022011 (rank : 614)
Query Neighborhood Hits	376	Target Neighborhood Hits	387	Shared Neighborhood Hits	47
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

EPN3_MOUSE
θ value	0.279714 (rank : 143)	NC score	0.046216 (rank : 521)
Query Neighborhood Hits	376	Target Neighborhood Hits	312	Shared Neighborhood Hits	59
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

EVL_HUMAN
θ value	0.279714 (rank : 144)	NC score	0.052699 (rank : 477)
Query Neighborhood Hits	376	Target Neighborhood Hits	260	Shared Neighborhood Hits	69
SwissProt Accessions	Q9UI08, O95884, Q7Z522, Q8TBV1, Q9UF25, Q9UIC2	Gene names	EVL, RNB6
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

FXL19_MOUSE
θ value	0.279714 (rank : 145)	NC score	0.027966 (rank : 586)
Query Neighborhood Hits	376	Target Neighborhood Hits	217	Shared Neighborhood Hits	28
SwissProt Accessions	Q6PB97, Q7TSH0, Q8BIB4	Gene names	Fbxl19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

GOGA6_HUMAN
θ value	0.279714 (rank : 146)	NC score	0.023459 (rank : 602)
Query Neighborhood Hits	376	Target Neighborhood Hits	1007	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

NRX2A_HUMAN
θ value	0.279714 (rank : 147)	NC score	0.034326 (rank : 554)
Query Neighborhood Hits	376	Target Neighborhood Hits	614	Shared Neighborhood Hits	60
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NRX2B_HUMAN
θ value	0.279714 (rank : 148)	NC score	0.050854 (rank : 505)
Query Neighborhood Hits	376	Target Neighborhood Hits	481	Shared Neighborhood Hits	55
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

RP1L1_HUMAN
θ value	0.279714 (rank : 149)	NC score	0.081553 (rank : 222)
Query Neighborhood Hits	376	Target Neighborhood Hits	1072	Shared Neighborhood Hits	118
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

SEPT9_MOUSE
θ value	0.279714 (rank : 150)	NC score	0.040144 (rank : 538)
Query Neighborhood Hits	376	Target Neighborhood Hits	238	Shared Neighborhood Hits	38
SwissProt Accessions	Q80UG5, Q3URP2, Q80TM7, Q9QYX9	Gene names	Sept9, Kiaa0991, Sint1
Domain Architecture	No domain graphic available
Description	Septin-9 (SL3-3 integration site 1 protein).

SSBP4_HUMAN
θ value	0.279714 (rank : 151)	NC score	0.047123 (rank : 518)
Query Neighborhood Hits	376	Target Neighborhood Hits	753	Shared Neighborhood Hits	87
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

SYNPO_HUMAN
θ value	0.279714 (rank : 152)	NC score	0.072066 (rank : 276)
Query Neighborhood Hits	376	Target Neighborhood Hits	281	Shared Neighborhood Hits	64
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

ADA12_MOUSE
θ value	0.365318 (rank : 153)	NC score	0.013372 (rank : 652)
Query Neighborhood Hits	376	Target Neighborhood Hits	474	Shared Neighborhood Hits	55
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

BI2L1_MOUSE
θ value	0.365318 (rank : 154)	NC score	0.032487 (rank : 565)
Query Neighborhood Hits	376	Target Neighborhood Hits	197	Shared Neighborhood Hits	27
SwissProt Accessions	Q9DBJ3	Gene names	Baiap2l1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

BRD8_MOUSE
θ value	0.365318 (rank : 155)	NC score	0.049465 (rank : 514)
Query Neighborhood Hits	376	Target Neighborhood Hits	422	Shared Neighborhood Hits	55
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

CECR2_HUMAN
θ value	0.365318 (rank : 156)	NC score	0.048679 (rank : 516)
Query Neighborhood Hits	376	Target Neighborhood Hits	543	Shared Neighborhood Hits	70
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

CJ108_HUMAN
θ value	0.365318 (rank : 157)	NC score	0.051799 (rank : 488)
Query Neighborhood Hits	376	Target Neighborhood Hits	165	Shared Neighborhood Hits	24
SwissProt Accessions	Q8N8Z3	Gene names	C10orf108
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C10orf108.

CP250_HUMAN
θ value	0.365318 (rank : 158)	NC score	0.024384 (rank : 597)
Query Neighborhood Hits	376	Target Neighborhood Hits	1805	Shared Neighborhood Hits	67
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

DCX_HUMAN
θ value	0.365318 (rank : 159)	NC score	0.027729 (rank : 588)
Query Neighborhood Hits	376	Target Neighborhood Hits	141	Shared Neighborhood Hits	23
SwissProt Accessions	O43602, O43911	Gene names	DCX, DBCN, LISX
Domain Architecture
Description	Neuronal migration protein doublecortin (Lissencephalin-X) (Lis-X) (Doublin).

FREA_HUMAN
θ value	0.365318 (rank : 160)	NC score	0.022981 (rank : 606)
Query Neighborhood Hits	376	Target Neighborhood Hits	205	Shared Neighborhood Hits	32
SwissProt Accessions	O43638, Q96D28	Gene names	FKHL18, FREAC10
Domain Architecture	No domain graphic available
Description	Forkhead-related transcription factor 10 (FREAC-10) (Forkhead-like 18 protein).

GGA2_HUMAN
θ value	0.365318 (rank : 161)	NC score	0.018916 (rank : 629)
Query Neighborhood Hits	376	Target Neighborhood Hits	114	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UJY4, O14564, Q9NYN2, Q9UPS2	Gene names	GGA2, KIAA1080
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA2 (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (Gamma-adaptin-related protein 2) (VHS domain and ear domain of gamma-adaptin) (Vear).

IL3B2_MOUSE
θ value	0.365318 (rank : 162)	NC score	0.053321 (rank : 463)
Query Neighborhood Hits	376	Target Neighborhood Hits	372	Shared Neighborhood Hits	48
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

P85B_HUMAN
θ value	0.365318 (rank : 163)	NC score	0.119419 (rank : 115)
Query Neighborhood Hits	376	Target Neighborhood Hits	543	Shared Neighborhood Hits	62
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

SOX30_HUMAN
θ value	0.365318 (rank : 164)	NC score	0.032759 (rank : 563)
Query Neighborhood Hits	376	Target Neighborhood Hits	305	Shared Neighborhood Hits	46
SwissProt Accessions	O94993, O94995, Q8IYX6	Gene names	SOX30
Domain Architecture
Description	Transcription factor SOX-30.

TACC2_HUMAN
θ value	0.365318 (rank : 165)	NC score	0.055658 (rank : 433)
Query Neighborhood Hits	376	Target Neighborhood Hits	856	Shared Neighborhood Hits	103
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

AATK_HUMAN
θ value	0.47712 (rank : 166)	NC score	0.014423 (rank : 646)
Query Neighborhood Hits	376	Target Neighborhood Hits	1243	Shared Neighborhood Hits	99
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

CASC3_MOUSE
θ value	0.47712 (rank : 167)	NC score	0.058409 (rank : 402)
Query Neighborhood Hits	376	Target Neighborhood Hits	333	Shared Neighborhood Hits	57
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

CUTL1_MOUSE
θ value	0.47712 (rank : 168)	NC score	0.039668 (rank : 540)
Query Neighborhood Hits	376	Target Neighborhood Hits	1620	Shared Neighborhood Hits	124
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

IL3RB_MOUSE
θ value	0.47712 (rank : 169)	NC score	0.055732 (rank : 432)
Query Neighborhood Hits	376	Target Neighborhood Hits	355	Shared Neighborhood Hits	46
SwissProt Accessions	P26955	Gene names	Csf2rb, Aic2b, Csf2rb1, Il3rb1
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen).

K1683_HUMAN
θ value	0.47712 (rank : 170)	NC score	0.099301 (rank : 157)
Query Neighborhood Hits	376	Target Neighborhood Hits	240	Shared Neighborhood Hits	46
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

MEGF9_MOUSE
θ value	0.47712 (rank : 171)	NC score	0.042349 (rank : 533)
Query Neighborhood Hits	376	Target Neighborhood Hits	896	Shared Neighborhood Hits	103
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MLL3_HUMAN
θ value	0.47712 (rank : 172)	NC score	0.082234 (rank : 219)
Query Neighborhood Hits	376	Target Neighborhood Hits	1644	Shared Neighborhood Hits	165
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

REST_MOUSE
θ value	0.47712 (rank : 173)	NC score	0.021481 (rank : 617)
Query Neighborhood Hits	376	Target Neighborhood Hits	1506	Shared Neighborhood Hits	64
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

SPEG_MOUSE
θ value	0.47712 (rank : 174)	NC score	0.023012 (rank : 604)
Query Neighborhood Hits	376	Target Neighborhood Hits	1959	Shared Neighborhood Hits	172
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

WNK2_HUMAN
θ value	0.47712 (rank : 175)	NC score	0.037814 (rank : 544)
Query Neighborhood Hits	376	Target Neighborhood Hits	1407	Shared Neighborhood Hits	177
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

ZAR1_HUMAN
θ value	0.47712 (rank : 176)	NC score	0.042080 (rank : 534)
Query Neighborhood Hits	376	Target Neighborhood Hits	163	Shared Neighborhood Hits	21
SwissProt Accessions	Q86SH2	Gene names	ZAR1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

CAMKV_HUMAN
θ value	0.62314 (rank : 177)	NC score	0.008500 (rank : 673)
Query Neighborhood Hits	376	Target Neighborhood Hits	1084	Shared Neighborhood Hits	68
SwissProt Accessions	Q8NCB2, Q6FIB8, Q8NBS8, Q8NC85, Q8NDU4, Q8WTT8, Q9BQC9, Q9H0Q5	Gene names	CAMKV
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

CF150_HUMAN
θ value	0.62314 (rank : 178)	NC score	0.068305 (rank : 301)
Query Neighborhood Hits	376	Target Neighborhood Hits	96	Shared Neighborhood Hits	22
SwissProt Accessions	Q8N884, Q32NC9, Q5SWL0, Q5SWL1, Q96E45	Gene names	C6orf150
Domain Architecture	No domain graphic available
Description	Protein C6orf150.

ERG_MOUSE
θ value	0.62314 (rank : 179)	NC score	0.014722 (rank : 644)
Query Neighborhood Hits	376	Target Neighborhood Hits	76	Shared Neighborhood Hits	8
SwissProt Accessions	P81270, Q8C5L4, Q920K7, Q920K8, Q920K9	Gene names	Erg, Erg-3
Domain Architecture
Description	Transcriptional regulator ERG.

FANCE_HUMAN
θ value	0.62314 (rank : 180)	NC score	0.035521 (rank : 551)
Query Neighborhood Hits	376	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HB96, Q4ZGH2	Gene names	FANCE
Domain Architecture	No domain graphic available
Description	Fanconi anemia group E protein (Protein FACE).

IF4G1_HUMAN
θ value	0.62314 (rank : 181)	NC score	0.075362 (rank : 246)
Query Neighborhood Hits	376	Target Neighborhood Hits	347	Shared Neighborhood Hits	92
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

NCOA6_MOUSE
θ value	0.62314 (rank : 182)	NC score	0.100379 (rank : 153)
Query Neighborhood Hits	376	Target Neighborhood Hits	1076	Shared Neighborhood Hits	139
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

T22D4_HUMAN
θ value	0.62314 (rank : 183)	NC score	0.045363 (rank : 524)
Query Neighborhood Hits	376	Target Neighborhood Hits	403	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

TAU_MOUSE
θ value	0.62314 (rank : 184)	NC score	0.079605 (rank : 225)
Query Neighborhood Hits	376	Target Neighborhood Hits	502	Shared Neighborhood Hits	87
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TENS4_HUMAN
θ value	0.62314 (rank : 185)	NC score	0.039216 (rank : 541)
Query Neighborhood Hits	376	Target Neighborhood Hits	214	Shared Neighborhood Hits	30
SwissProt Accessions	Q8IZW8, Q71RB7, Q8WV64, Q96JV4	Gene names	TNS4, CTEN
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor (C-terminal tensin-like protein).

TS13_MOUSE
θ value	0.62314 (rank : 186)	NC score	0.051363 (rank : 500)
Query Neighborhood Hits	376	Target Neighborhood Hits	191	Shared Neighborhood Hits	20
SwissProt Accessions	Q01755	Gene names	Tcp11
Domain Architecture
Description	Testis-specific protein PBS13.

UBQL3_MOUSE
θ value	0.62314 (rank : 187)	NC score	0.022829 (rank : 607)
Query Neighborhood Hits	376	Target Neighborhood Hits	120	Shared Neighborhood Hits	12
SwissProt Accessions	Q8C5U9	Gene names	Ubqln3
Domain Architecture
Description	Ubiquilin-3.

AAK1_MOUSE
θ value	0.813845 (rank : 188)	NC score	0.024303 (rank : 598)
Query Neighborhood Hits	376	Target Neighborhood Hits	1051	Shared Neighborhood Hits	80
SwissProt Accessions	Q3UHJ0, Q3TY53, Q6ZPZ6, Q80XP6	Gene names	Aak1, Kiaa1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

AL2S4_MOUSE
θ value	0.813845 (rank : 189)	NC score	0.055232 (rank : 439)
Query Neighborhood Hits	376	Target Neighborhood Hits	193	Shared Neighborhood Hits	32
SwissProt Accessions	Q3V0J1, Q3TIS2	Gene names	Als2cr4
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein homolog.

ARMX2_MOUSE
θ value	0.813845 (rank : 190)	NC score	0.049515 (rank : 513)
Query Neighborhood Hits	376	Target Neighborhood Hits	349	Shared Neighborhood Hits	58
SwissProt Accessions	Q6A058, Q9CXI9	Gene names	Armcx2, Kiaa0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2.

GA2L2_HUMAN
θ value	0.813845 (rank : 191)	NC score	0.037397 (rank : 546)
Query Neighborhood Hits	376	Target Neighborhood Hits	175	Shared Neighborhood Hits	38
SwissProt Accessions	Q8NHY3, Q8NHY4	Gene names	GAS2L2, GAR17
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2) (GAS2-related protein on chromosome 17) (GAR17 protein).

GAK2_HUMAN
θ value	0.813845 (rank : 192)	NC score	0.033034 (rank : 561)
Query Neighborhood Hits	376	Target Neighborhood Hits	406	Shared Neighborhood Hits	55
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GNAS1_MOUSE
θ value	0.813845 (rank : 193)	NC score	0.053349 (rank : 462)
Query Neighborhood Hits	376	Target Neighborhood Hits	651	Shared Neighborhood Hits	101
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

GOGB1_HUMAN
θ value	0.813845 (rank : 194)	NC score	0.031288 (rank : 570)
Query Neighborhood Hits	376	Target Neighborhood Hits	2297	Shared Neighborhood Hits	87
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

MK15_HUMAN
θ value	0.813845 (rank : 195)	NC score	0.003593 (rank : 686)
Query Neighborhood Hits	376	Target Neighborhood Hits	1038	Shared Neighborhood Hits	51
SwissProt Accessions	Q8TD08, Q2TCF9, Q8N362	Gene names	MAPK15, ERK8
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 8).

MYH4_HUMAN
θ value	0.813845 (rank : 196)	NC score	0.035880 (rank : 550)
Query Neighborhood Hits	376	Target Neighborhood Hits	1377	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

RAI1_MOUSE
θ value	0.813845 (rank : 197)	NC score	0.051382 (rank : 498)
Query Neighborhood Hits	376	Target Neighborhood Hits	344	Shared Neighborhood Hits	57
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

ZN385_HUMAN
θ value	0.813845 (rank : 198)	NC score	0.052172 (rank : 483)
Query Neighborhood Hits	376	Target Neighborhood Hits	614	Shared Neighborhood Hits	65
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

3BP2_HUMAN
θ value	1.06291 (rank : 199)	NC score	0.074242 (rank : 257)
Query Neighborhood Hits	376	Target Neighborhood Hits	296	Shared Neighborhood Hits	52
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

C2TA_HUMAN
θ value	1.06291 (rank : 200)	NC score	0.027873 (rank : 587)
Query Neighborhood Hits	376	Target Neighborhood Hits	190	Shared Neighborhood Hits	33
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

CRSP2_HUMAN
θ value	1.06291 (rank : 201)	NC score	0.068410 (rank : 299)
Query Neighborhood Hits	376	Target Neighborhood Hits	380	Shared Neighborhood Hits	67
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

DOCK4_MOUSE
θ value	1.06291 (rank : 202)	NC score	0.042789 (rank : 529)
Query Neighborhood Hits	376	Target Neighborhood Hits	210	Shared Neighborhood Hits	46
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

EGR4_HUMAN
θ value	1.06291 (rank : 203)	NC score	-0.001686 (rank : 698)
Query Neighborhood Hits	376	Target Neighborhood Hits	939	Shared Neighborhood Hits	37
SwissProt Accessions	Q05215	Gene names	EGR4
Domain Architecture
Description	Early growth response protein 4 (EGR-4) (AT133).

FREA_MOUSE
θ value	1.06291 (rank : 204)	NC score	0.018264 (rank : 631)
Query Neighborhood Hits	376	Target Neighborhood Hits	147	Shared Neighborhood Hits	23
SwissProt Accessions	Q61574, Q8C5N7	Gene names	Fkhl18, Fkh3, Freac10
Domain Architecture	No domain graphic available
Description	Forkhead-related transcription factor 10 (FREAC-10) (Forkhead-like 18 protein) (Transcription factor FKH-3).

GAB1_MOUSE
θ value	1.06291 (rank : 205)	NC score	0.050536 (rank : 508)
Query Neighborhood Hits	376	Target Neighborhood Hits	233	Shared Neighborhood Hits	32
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

GAK5_HUMAN
θ value	1.06291 (rank : 206)	NC score	0.031945 (rank : 567)
Query Neighborhood Hits	376	Target Neighborhood Hits	429	Shared Neighborhood Hits	54
SwissProt Accessions	P62684	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K113 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

KSR2_HUMAN
θ value	1.06291 (rank : 207)	NC score	0.010536 (rank : 667)
Query Neighborhood Hits	376	Target Neighborhood Hits	920	Shared Neighborhood Hits	56
SwissProt Accessions	Q6VAB6, Q8N775	Gene names	KSR2
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-2 (hKSR2).

MAGD4_HUMAN
θ value	1.06291 (rank : 208)	NC score	0.029892 (rank : 578)
Query Neighborhood Hits	376	Target Neighborhood Hits	338	Shared Neighborhood Hits	57
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

MAST1_HUMAN
θ value	1.06291 (rank : 209)	NC score	0.005479 (rank : 681)
Query Neighborhood Hits	376	Target Neighborhood Hits	1146	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MKL1_MOUSE
θ value	1.06291 (rank : 210)	NC score	0.056681 (rank : 418)
Query Neighborhood Hits	376	Target Neighborhood Hits	667	Shared Neighborhood Hits	90
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

MTR1L_HUMAN
θ value	1.06291 (rank : 211)	NC score	0.000395 (rank : 694)
Query Neighborhood Hits	376	Target Neighborhood Hits	1180	Shared Neighborhood Hits	51
SwissProt Accessions	Q13585	Gene names	GPR50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).

PAX7_HUMAN
θ value	1.06291 (rank : 212)	NC score	0.007467 (rank : 677)
Query Neighborhood Hits	376	Target Neighborhood Hits	456	Shared Neighborhood Hits	23
SwissProt Accessions	P23759	Gene names	PAX7, HUP1
Domain Architecture
Description	Paired box protein Pax-7 (HUP1).

TSH2_HUMAN
θ value	1.06291 (rank : 213)	NC score	0.012950 (rank : 653)
Query Neighborhood Hits	376	Target Neighborhood Hits	479	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NRE2, Q4VXM4, Q6N003, Q8N260	Gene names	TSHZ2, C20orf17, TSH2, ZNF218
Domain Architecture	No domain graphic available
Description	Teashirt homolog 2 (Zinc finger protein 218) (Ovarian cancer-related protein 10-2) (OVC10-2).

UBQL4_MOUSE
θ value	1.06291 (rank : 214)	NC score	0.020847 (rank : 620)
Query Neighborhood Hits	376	Target Neighborhood Hits	99	Shared Neighborhood Hits	18
SwissProt Accessions	Q99NB8, Q8BP88	Gene names	Ubqln4, Ubin
Domain Architecture
Description	Ubiquilin-4 (Ataxin-1 ubiquitin-like-interacting protein A1U).

DCP1A_HUMAN
θ value	1.38821 (rank : 215)	NC score	0.042559 (rank : 530)
Query Neighborhood Hits	376	Target Neighborhood Hits	228	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NPI6	Gene names	DCP1A, SMIF
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (Smad4-interacting transcriptional co-activator).

DIDO1_HUMAN
θ value	1.38821 (rank : 216)	NC score	0.055353 (rank : 437)
Query Neighborhood Hits	376	Target Neighborhood Hits	960	Shared Neighborhood Hits	109
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

FOXC2_HUMAN
θ value	1.38821 (rank : 217)	NC score	0.014276 (rank : 647)
Query Neighborhood Hits	376	Target Neighborhood Hits	236	Shared Neighborhood Hits	29
SwissProt Accessions	Q99958	Gene names	FOXC2, FKHL14, MFH1
Domain Architecture
Description	Forkhead box protein C2 (Forkhead-related protein FKHL14) (Mesenchyme fork head protein 1) (MFH-1 protein) (Transcription factor FKH-14).

GAK11_HUMAN
θ value	1.38821 (rank : 218)	NC score	0.033317 (rank : 560)
Query Neighborhood Hits	376	Target Neighborhood Hits	409	Shared Neighborhood Hits	57
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK4_HUMAN
θ value	1.38821 (rank : 219)	NC score	0.033506 (rank : 558)
Query Neighborhood Hits	376	Target Neighborhood Hits	415	Shared Neighborhood Hits	58
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GLI2_HUMAN
θ value	1.38821 (rank : 220)	NC score	-0.002206 (rank : 699)
Query Neighborhood Hits	376	Target Neighborhood Hits	971	Shared Neighborhood Hits	51
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

IL4RA_MOUSE
θ value	1.38821 (rank : 221)	NC score	0.033510 (rank : 557)
Query Neighborhood Hits	376	Target Neighborhood Hits	194	Shared Neighborhood Hits	30
SwissProt Accessions	P16382, O54690, Q60583, Q8CBW5	Gene names	Il4r, Il4ra
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (IL-4- binding protein) (IL4-BP)].

ITSN1_HUMAN
θ value	1.38821 (rank : 222)	NC score	0.067079 (rank : 312)
Query Neighborhood Hits	376	Target Neighborhood Hits	1757	Shared Neighborhood Hits	123
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

MEF2B_MOUSE
θ value	1.38821 (rank : 223)	NC score	0.032582 (rank : 564)
Query Neighborhood Hits	376	Target Neighborhood Hits	218	Shared Neighborhood Hits	32
SwissProt Accessions	O55087, O55088, O55089, O55090, O55231, Q61843	Gene names	Mef2b
Domain Architecture
Description	Myocyte-specific enhancer factor 2B.

MKRN3_HUMAN
θ value	1.38821 (rank : 224)	NC score	0.011275 (rank : 660)
Query Neighborhood Hits	376	Target Neighborhood Hits	165	Shared Neighborhood Hits	8
SwissProt Accessions	Q13064	Gene names	MKRN3, RNF63, ZNF127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127) (RING finger protein 63).

MMAC_HUMAN
θ value	1.38821 (rank : 225)	NC score	0.024687 (rank : 596)
Query Neighborhood Hits	376	Target Neighborhood Hits	76	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y4U1, Q5T157, Q9BRQ7	Gene names	MMACHC
Domain Architecture	No domain graphic available
Description	Methylmalonic aciduria and homocystinuria type C protein.

NUP53_MOUSE
θ value	1.38821 (rank : 226)	NC score	0.030556 (rank : 573)
Query Neighborhood Hits	376	Target Neighborhood Hits	94	Shared Neighborhood Hits	19
SwissProt Accessions	Q8R4R6, Q9D7J2	Gene names	Nup35, Mp44, Nup53
Domain Architecture	No domain graphic available
Description	Nucleoporin NUP53 (Nuclear pore complex protein Nup53) (Nucleoporin Nup35) (35 kDa nucleoporin) (Mitotic phosphoprotein 44) (MP-44).

BAZ2A_MOUSE
θ value	1.81305 (rank : 227)	NC score	0.052014 (rank : 485)
Query Neighborhood Hits	376	Target Neighborhood Hits	744	Shared Neighborhood Hits	102
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

FOG1_MOUSE
θ value	1.81305 (rank : 228)	NC score	0.025338 (rank : 594)
Query Neighborhood Hits	376	Target Neighborhood Hits	1237	Shared Neighborhood Hits	124
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

HSF1_MOUSE
θ value	1.81305 (rank : 229)	NC score	0.037752 (rank : 545)
Query Neighborhood Hits	376	Target Neighborhood Hits	267	Shared Neighborhood Hits	45
SwissProt Accessions	P38532, O70462	Gene names	Hsf1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

MAP4_HUMAN
θ value	1.81305 (rank : 230)	NC score	0.092936 (rank : 175)
Query Neighborhood Hits	376	Target Neighborhood Hits	428	Shared Neighborhood Hits	84
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MINT_MOUSE
θ value	1.81305 (rank : 231)	NC score	0.081421 (rank : 223)
Query Neighborhood Hits	376	Target Neighborhood Hits	1514	Shared Neighborhood Hits	164
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MUCDL_MOUSE
θ value	1.81305 (rank : 232)	NC score	0.067344 (rank : 310)
Query Neighborhood Hits	376	Target Neighborhood Hits	461	Shared Neighborhood Hits	88
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

NIN_HUMAN
θ value	1.81305 (rank : 233)	NC score	0.026466 (rank : 591)
Query Neighborhood Hits	376	Target Neighborhood Hits	1416	Shared Neighborhood Hits	64
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

NSD1_MOUSE
θ value	1.81305 (rank : 234)	NC score	0.049030 (rank : 515)
Query Neighborhood Hits	376	Target Neighborhood Hits	472	Shared Neighborhood Hits	66
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

RTKN_HUMAN
θ value	1.81305 (rank : 235)	NC score	0.029079 (rank : 579)
Query Neighborhood Hits	376	Target Neighborhood Hits	97	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BST9, Q8WVN1, Q96PT6, Q9HB05	Gene names	RTKN
Domain Architecture	No domain graphic available
Description	Rhotekin.

SEZ6L_HUMAN
θ value	1.81305 (rank : 236)	NC score	0.024133 (rank : 599)
Query Neighborhood Hits	376	Target Neighborhood Hits	289	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

SF3B1_HUMAN
θ value	1.81305 (rank : 237)	NC score	0.051568 (rank : 494)
Query Neighborhood Hits	376	Target Neighborhood Hits	341	Shared Neighborhood Hits	48
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_MOUSE
θ value	1.81305 (rank : 238)	NC score	0.050490 (rank : 509)
Query Neighborhood Hits	376	Target Neighborhood Hits	352	Shared Neighborhood Hits	48
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

ZIM10_HUMAN
θ value	1.81305 (rank : 239)	NC score	0.038301 (rank : 543)
Query Neighborhood Hits	376	Target Neighborhood Hits	577	Shared Neighborhood Hits	74
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ZN687_HUMAN
θ value	1.81305 (rank : 240)	NC score	0.022815 (rank : 608)
Query Neighborhood Hits	376	Target Neighborhood Hits	1244	Shared Neighborhood Hits	92
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

AMPH_HUMAN
θ value	2.36792 (rank : 241)	NC score	0.052797 (rank : 474)
Query Neighborhood Hits	376	Target Neighborhood Hits	455	Shared Neighborhood Hits	70
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

COA2_HUMAN
θ value	2.36792 (rank : 242)	NC score	0.022206 (rank : 611)
Query Neighborhood Hits	376	Target Neighborhood Hits	184	Shared Neighborhood Hits	24
SwissProt Accessions	O00763, Q16852	Gene names	ACACB, ACC2, ACCB
Domain Architecture
Description	Acetyl-CoA carboxylase 2 (EC 6.4.1.2) (ACC-beta) [Includes: Biotin carboxylase (EC 6.3.4.14)].

E2F4_HUMAN
θ value	2.36792 (rank : 243)	NC score	0.025701 (rank : 592)
Query Neighborhood Hits	376	Target Neighborhood Hits	188	Shared Neighborhood Hits	38
SwissProt Accessions	Q16254, Q12991, Q15328	Gene names	E2F4
Domain Architecture
Description	Transcription factor E2F4 (E2F-4).

EPHB6_HUMAN
θ value	2.36792 (rank : 244)	NC score	0.001579 (rank : 692)
Query Neighborhood Hits	376	Target Neighborhood Hits	912	Shared Neighborhood Hits	31
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

FMN2_MOUSE
θ value	2.36792 (rank : 245)	NC score	0.074175 (rank : 260)
Query Neighborhood Hits	376	Target Neighborhood Hits	349	Shared Neighborhood Hits	90
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

GAK6_HUMAN
θ value	2.36792 (rank : 246)	NC score	0.031434 (rank : 569)
Query Neighborhood Hits	376	Target Neighborhood Hits	392	Shared Neighborhood Hits	55
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

LIMD1_HUMAN
θ value	2.36792 (rank : 247)	NC score	0.014849 (rank : 643)
Query Neighborhood Hits	376	Target Neighborhood Hits	201	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UGP4, Q9BQQ9, Q9NQ47	Gene names	LIMD1
Domain Architecture
Description	LIM domain-containing protein 1.

LTB1L_HUMAN
θ value	2.36792 (rank : 248)	NC score	0.021833 (rank : 616)
Query Neighborhood Hits	376	Target Neighborhood Hits	553	Shared Neighborhood Hits	34
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	2.36792 (rank : 249)	NC score	0.020551 (rank : 621)
Query Neighborhood Hits	376	Target Neighborhood Hits	502	Shared Neighborhood Hits	25
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTK_MOUSE
θ value	2.36792 (rank : 250)	NC score	-0.001481 (rank : 697)
Query Neighborhood Hits	376	Target Neighborhood Hits	770	Shared Neighborhood Hits	20
SwissProt Accessions	P08923	Gene names	Ltk
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1).

MUC5B_HUMAN
θ value	2.36792 (rank : 251)	NC score	0.066077 (rank : 316)
Query Neighborhood Hits	376	Target Neighborhood Hits	1020	Shared Neighborhood Hits	123
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

MUCDL_HUMAN
θ value	2.36792 (rank : 252)	NC score	0.078780 (rank : 229)
Query Neighborhood Hits	376	Target Neighborhood Hits	777	Shared Neighborhood Hits	111
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

PAX7_MOUSE
θ value	2.36792 (rank : 253)	NC score	0.006116 (rank : 678)
Query Neighborhood Hits	376	Target Neighborhood Hits	422	Shared Neighborhood Hits	17
SwissProt Accessions	P47239, Q9ES16	Gene names	Pax7, Pax-7
Domain Architecture	No domain graphic available
Description	Paired box protein Pax-7.

PAX9_HUMAN
θ value	2.36792 (rank : 254)	NC score	0.016362 (rank : 636)
Query Neighborhood Hits	376	Target Neighborhood Hits	92	Shared Neighborhood Hits	16
SwissProt Accessions	P55771, Q99582, Q9UQR4	Gene names	PAX9
Domain Architecture
Description	Paired box protein Pax-9.

PHLB1_HUMAN
θ value	2.36792 (rank : 255)	NC score	0.053107 (rank : 466)
Query Neighborhood Hits	376	Target Neighborhood Hits	1038	Shared Neighborhood Hits	122
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PHLPP_HUMAN
θ value	2.36792 (rank : 256)	NC score	0.024853 (rank : 595)
Query Neighborhood Hits	376	Target Neighborhood Hits	604	Shared Neighborhood Hits	66
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

SRBS1_MOUSE
θ value	2.36792 (rank : 257)	NC score	0.090617 (rank : 185)
Query Neighborhood Hits	376	Target Neighborhood Hits	409	Shared Neighborhood Hits	64
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SYNP2_HUMAN
θ value	2.36792 (rank : 258)	NC score	0.042371 (rank : 532)
Query Neighborhood Hits	376	Target Neighborhood Hits	323	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

TACC3_HUMAN
θ value	2.36792 (rank : 259)	NC score	0.054927 (rank : 446)
Query Neighborhood Hits	376	Target Neighborhood Hits	779	Shared Neighborhood Hits	84
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

TBX2_HUMAN
θ value	2.36792 (rank : 260)	NC score	0.010713 (rank : 666)
Query Neighborhood Hits	376	Target Neighborhood Hits	195	Shared Neighborhood Hits	24
SwissProt Accessions	Q13207, Q16424, Q7Z647	Gene names	TBX2
Domain Architecture
Description	T-box transcription factor TBX2 (T-box protein 2).

TIEG3_MOUSE
θ value	2.36792 (rank : 261)	NC score	-0.003275 (rank : 700)
Query Neighborhood Hits	376	Target Neighborhood Hits	774	Shared Neighborhood Hits	26
SwissProt Accessions	Q8K1S5, Q8BI37	Gene names	Tieg3, Tieg2b
Domain Architecture
Description	Transforming growth factor-beta-inducible early growth response protein 3 (TGFB-inducible early growth response protein 3) (TIEG-3) (TGFB-inducible early growth response protein 2b).

ZEP2_HUMAN
θ value	2.36792 (rank : 262)	NC score	0.005658 (rank : 680)
Query Neighborhood Hits	376	Target Neighborhood Hits	937	Shared Neighborhood Hits	42
SwissProt Accessions	P31629, Q02646, Q5THT5, Q9NS05	Gene names	HIVEP2
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 (HIV- EP2) (MHC-binding protein 2) (MBP-2).

ZW10_MOUSE
θ value	2.36792 (rank : 263)	NC score	0.015854 (rank : 638)
Query Neighborhood Hits	376	Target Neighborhood Hits	86	Shared Neighborhood Hits	5
SwissProt Accessions	O54692, Q3TIA5, Q3ULW1, Q921H3	Gene names	Zw10
Domain Architecture	No domain graphic available
Description	Centromere/kinetochore protein zw10 homolog.

DCX_MOUSE
θ value	3.0926 (rank : 264)	NC score	0.023560 (rank : 601)
Query Neighborhood Hits	376	Target Neighborhood Hits	124	Shared Neighborhood Hits	21
SwissProt Accessions	O88809	Gene names	Dcx, Dcn
Domain Architecture
Description	Neuronal migration protein doublecortin (Lissencephalin-X) (Lis-X) (Doublin).

ERG_HUMAN
θ value	3.0926 (rank : 265)	NC score	0.011619 (rank : 658)
Query Neighborhood Hits	376	Target Neighborhood Hits	86	Shared Neighborhood Hits	8
SwissProt Accessions	P11308, Q16113	Gene names	ERG
Domain Architecture
Description	Transcriptional regulator ERG (Transforming protein ERG).

ETV5_MOUSE
θ value	3.0926 (rank : 266)	NC score	0.020544 (rank : 622)
Query Neighborhood Hits	376	Target Neighborhood Hits	328	Shared Neighborhood Hits	42
SwissProt Accessions	Q9CXC9, Q3TG49, Q8C0F3, Q9JHB1	Gene names	Etv5
Domain Architecture	No domain graphic available
Description	ETS translocation variant 5.

FOXK1_MOUSE
θ value	3.0926 (rank : 267)	NC score	0.012622 (rank : 654)
Query Neighborhood Hits	376	Target Neighborhood Hits	215	Shared Neighborhood Hits	24
SwissProt Accessions	P42128, O35939	Gene names	Foxk1, Mnf
Domain Architecture
Description	Forkhead box protein K1 (Myocyte nuclear factor) (MNF).

FOXK2_HUMAN
θ value	3.0926 (rank : 268)	NC score	0.015014 (rank : 641)
Query Neighborhood Hits	376	Target Neighborhood Hits	190	Shared Neighborhood Hits	25
SwissProt Accessions	Q01167, Q13622, Q13623, Q13624	Gene names	FOXK2, ILF, ILF1
Domain Architecture
Description	Forkhead box protein K2 (Interleukin enhancer-binding factor 1) (Cellular transcription factor ILF-1).

IF4G1_MOUSE
θ value	3.0926 (rank : 269)	NC score	0.061974 (rank : 353)
Query Neighborhood Hits	376	Target Neighborhood Hits	534	Shared Neighborhood Hits	81
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

JIP1_MOUSE
θ value	3.0926 (rank : 270)	NC score	0.032218 (rank : 566)
Query Neighborhood Hits	376	Target Neighborhood Hits	259	Shared Neighborhood Hits	39
SwissProt Accessions	Q9WVI9, O35145, Q925J8, Q9R1H9, Q9R1Z1, Q9WVI7, Q9WVI8	Gene names	Mapk8ip1, Ib1, Jip1, Mapk8ip, Prkm8ip
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain-1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

M3KL4_HUMAN
θ value	3.0926 (rank : 271)	NC score	0.005352 (rank : 682)
Query Neighborhood Hits	376	Target Neighborhood Hits	1087	Shared Neighborhood Hits	48
SwissProt Accessions	Q5TCX8, Q5TCX7, Q5TCX9, Q8WWN1, Q8WWN2, Q96JM1	Gene names	MLK4, KIAA1804
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase 4).

MAST4_HUMAN
θ value	3.0926 (rank : 272)	NC score	0.020876 (rank : 619)
Query Neighborhood Hits	376	Target Neighborhood Hits	1804	Shared Neighborhood Hits	150
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

NCOR2_HUMAN
θ value	3.0926 (rank : 273)	NC score	0.086527 (rank : 200)
Query Neighborhood Hits	376	Target Neighborhood Hits	870	Shared Neighborhood Hits	151
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

PTPRG_HUMAN
θ value	3.0926 (rank : 274)	NC score	0.002647 (rank : 690)
Query Neighborhood Hits	376	Target Neighborhood Hits	231	Shared Neighborhood Hits	18
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

RAI2_MOUSE
θ value	3.0926 (rank : 275)	NC score	0.017854 (rank : 632)
Query Neighborhood Hits	376	Target Neighborhood Hits	58	Shared Neighborhood Hits	12
SwissProt Accessions	Q9QVY8	Gene names	Rai2
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 2 (3f8).

RBBP6_MOUSE
θ value	3.0926 (rank : 276)	NC score	0.037185 (rank : 547)
Query Neighborhood Hits	376	Target Neighborhood Hits	1014	Shared Neighborhood Hits	88
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

S23IP_MOUSE
θ value	3.0926 (rank : 277)	NC score	0.061026 (rank : 359)
Query Neighborhood Hits	376	Target Neighborhood Hits	363	Shared Neighborhood Hits	76
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

SVIL_MOUSE
θ value	3.0926 (rank : 278)	NC score	0.033867 (rank : 556)
Query Neighborhood Hits	376	Target Neighborhood Hits	439	Shared Neighborhood Hits	46
SwissProt Accessions	Q8K4L3	Gene names	Svil
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

TFE2_MOUSE
θ value	3.0926 (rank : 279)	NC score	0.011770 (rank : 656)
Query Neighborhood Hits	376	Target Neighborhood Hits	118	Shared Neighborhood Hits	14
SwissProt Accessions	P15806, Q3U153, Q8CAH9, Q8VCY4, Q922S2, Q99MB8, Q9CYJ4	Gene names	Tcf3, Alf2, Me2, Tcfe2a
Domain Architecture	No domain graphic available
Description	Transcription factor E2-alpha (Immunoglobulin enhancer-binding factor E12/E47) (Transcription factor 3) (TCF-3) (Transcription factor A1).

ANTR2_HUMAN
θ value	4.03905 (rank : 280)	NC score	0.009204 (rank : 669)
Query Neighborhood Hits	376	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	P58335, Q59E98, Q5JPE9, Q86UI1, Q8N4J8, Q8NB13, Q96NC7	Gene names	ANTXR2, CMG2
Domain Architecture
Description	Anthrax toxin receptor 2 precursor (Capillary morphogenesis gene 2 protein) (CMG-2).

BAG3_HUMAN
θ value	4.03905 (rank : 281)	NC score	0.077517 (rank : 238)
Query Neighborhood Hits	376	Target Neighborhood Hits	314	Shared Neighborhood Hits	75
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

BAG3_MOUSE
θ value	4.03905 (rank : 282)	NC score	0.086476 (rank : 202)
Query Neighborhood Hits	376	Target Neighborhood Hits	513	Shared Neighborhood Hits	109
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

CEP41_HUMAN
θ value	4.03905 (rank : 283)	NC score	0.016351 (rank : 637)
Query Neighborhood Hits	376	Target Neighborhood Hits	42	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BYV8, Q7Z496, Q86TM1, Q8NFU8, Q9H6A3, Q9NPV3	Gene names	TSGA14, CEP41
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 41 kDa (Cep41 protein) (Testis-specific gene A14 protein).

CSKI1_HUMAN
θ value	4.03905 (rank : 284)	NC score	0.075594 (rank : 245)
Query Neighborhood Hits	376	Target Neighborhood Hits	997	Shared Neighborhood Hits	157
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

FGFP3_HUMAN
θ value	4.03905 (rank : 285)	NC score	0.019114 (rank : 627)
Query Neighborhood Hits	376	Target Neighborhood Hits	54	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TAT2, Q8NBN0	Gene names	FGFBP3, C10orf13
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor-binding protein 3 precursor (FGF-binding protein 3) (FGF-BP3) (FGFBP-3).

GA2L2_MOUSE
θ value	4.03905 (rank : 286)	NC score	0.040050 (rank : 539)
Query Neighborhood Hits	376	Target Neighborhood Hits	395	Shared Neighborhood Hits	64
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

GCC2_MOUSE
θ value	4.03905 (rank : 287)	NC score	0.020445 (rank : 625)
Query Neighborhood Hits	376	Target Neighborhood Hits	1619	Shared Neighborhood Hits	58
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

LARP4_MOUSE
θ value	4.03905 (rank : 288)	NC score	0.039175 (rank : 542)
Query Neighborhood Hits	376	Target Neighborhood Hits	260	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BWW4, Q3UR69	Gene names	Larp4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

MAP4_MOUSE
θ value	4.03905 (rank : 289)	NC score	0.097870 (rank : 160)
Query Neighborhood Hits	376	Target Neighborhood Hits	409	Shared Neighborhood Hits	90
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

NCTR2_HUMAN
θ value	4.03905 (rank : 290)	NC score	0.022759 (rank : 609)
Query Neighborhood Hits	376	Target Neighborhood Hits	99	Shared Neighborhood Hits	15
SwissProt Accessions	O95944, Q9H562, Q9H563, Q9H564, Q9UMT1, Q9UMT2	Gene names	NCR2, LY95
Domain Architecture
Description	Natural cytotoxicity triggering receptor 2 precursor (Natural killer cell p44-related protein) (NKp44) (NK-p44) (NK cell-activating receptor) (Lymphocyte antigen 95 homolog) (CD336 antigen).

NIN_MOUSE
θ value	4.03905 (rank : 291)	NC score	0.020469 (rank : 624)
Query Neighborhood Hits	376	Target Neighborhood Hits	1376	Shared Neighborhood Hits	52
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

NUMBL_HUMAN
θ value	4.03905 (rank : 292)	NC score	0.029001 (rank : 580)
Query Neighborhood Hits	376	Target Neighborhood Hits	394	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

OBSCN_HUMAN
θ value	4.03905 (rank : 293)	NC score	0.011678 (rank : 657)
Query Neighborhood Hits	376	Target Neighborhood Hits	1931	Shared Neighborhood Hits	114
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

PSMF1_MOUSE
θ value	4.03905 (rank : 294)	NC score	0.015741 (rank : 639)
Query Neighborhood Hits	376	Target Neighborhood Hits	85	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BHL8, Q8C0G9	Gene names	Psmf1
Domain Architecture	No domain graphic available
Description	Proteasome inhibitor PI31 subunit.

ROCK2_MOUSE
θ value	4.03905 (rank : 295)	NC score	0.008711 (rank : 672)
Query Neighborhood Hits	376	Target Neighborhood Hits	2072	Shared Neighborhood Hits	65
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

RUSC2_MOUSE
θ value	4.03905 (rank : 296)	NC score	0.046950 (rank : 519)
Query Neighborhood Hits	376	Target Neighborhood Hits	305	Shared Neighborhood Hits	63
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

SH22A_MOUSE
θ value	4.03905 (rank : 297)	NC score	0.010912 (rank : 664)
Query Neighborhood Hits	376	Target Neighborhood Hits	179	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QXK9, Q9JHP6	Gene names	Sh2d2a, Lad, Ribp
Domain Architecture
Description	SH2 domain protein 2A (Lck-associated adapter protein) (Lad) (Rlk/Itk- binding protein) (Ribp).

SNPC4_HUMAN
θ value	4.03905 (rank : 298)	NC score	0.059600 (rank : 384)
Query Neighborhood Hits	376	Target Neighborhood Hits	589	Shared Neighborhood Hits	97
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

SRRM2_HUMAN
θ value	4.03905 (rank : 299)	NC score	0.140948 (rank : 80)
Query Neighborhood Hits	376	Target Neighborhood Hits	1296	Shared Neighborhood Hits	189
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SYNJ1_HUMAN
θ value	4.03905 (rank : 300)	NC score	0.127419 (rank : 102)
Query Neighborhood Hits	376	Target Neighborhood Hits	498	Shared Neighborhood Hits	144
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

ADDB_MOUSE
θ value	5.27518 (rank : 301)	NC score	0.028621 (rank : 582)
Query Neighborhood Hits	376	Target Neighborhood Hits	574	Shared Neighborhood Hits	57
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

CN145_HUMAN
θ value	5.27518 (rank : 302)	NC score	0.021013 (rank : 618)
Query Neighborhood Hits	376	Target Neighborhood Hits	1196	Shared Neighborhood Hits	50
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

DPOLL_MOUSE
θ value	5.27518 (rank : 303)	NC score	0.014634 (rank : 645)
Query Neighborhood Hits	376	Target Neighborhood Hits	71	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QXE2, Q9CTJ1	Gene names	Poll, Polk
Domain Architecture
Description	DNA polymerase lambda (EC 2.7.7.7) (EC 4.2.99.-) (Pol Lambda) (DNA polymerase kappa).

HXD3_MOUSE
θ value	5.27518 (rank : 304)	NC score	0.003475 (rank : 687)
Query Neighborhood Hits	376	Target Neighborhood Hits	435	Shared Neighborhood Hits	36
SwissProt Accessions	P09027, Q3UUD3	Gene names	Hoxd3, Hox-4.1, Hoxd-3
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4.1) (Homeobox protein MH-19).

ITSN1_MOUSE
θ value	5.27518 (rank : 305)	NC score	0.064512 (rank : 328)
Query Neighborhood Hits	376	Target Neighborhood Hits	1669	Shared Neighborhood Hits	113
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

LDB3_MOUSE
θ value	5.27518 (rank : 306)	NC score	0.051935 (rank : 487)
Query Neighborhood Hits	376	Target Neighborhood Hits	510	Shared Neighborhood Hits	111
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

NSD1_HUMAN
θ value	5.27518 (rank : 307)	NC score	0.045579 (rank : 523)
Query Neighborhood Hits	376	Target Neighborhood Hits	427	Shared Neighborhood Hits	58
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

PANK1_HUMAN
θ value	5.27518 (rank : 308)	NC score	0.008292 (rank : 676)
Query Neighborhood Hits	376	Target Neighborhood Hits	75	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TE04, Q7RTX6, Q7Z495, Q8TBQ8	Gene names	PANK1, PANK
Domain Architecture
Description	Pantothenate kinase 1 (EC 2.7.1.33) (Pantothenic acid kinase 1) (hPanK1) (hPanK).

PO121_MOUSE
θ value	5.27518 (rank : 309)	NC score	0.098359 (rank : 159)
Query Neighborhood Hits	376	Target Neighborhood Hits	345	Shared Neighborhood Hits	84
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

SETBP_MOUSE
θ value	5.27518 (rank : 310)	NC score	0.044658 (rank : 526)
Query Neighborhood Hits	376	Target Neighborhood Hits	352	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

SOX13_HUMAN
θ value	5.27518 (rank : 311)	NC score	0.030094 (rank : 576)
Query Neighborhood Hits	376	Target Neighborhood Hits	464	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

TLE4_HUMAN
θ value	5.27518 (rank : 312)	NC score	0.011100 (rank : 662)
Query Neighborhood Hits	376	Target Neighborhood Hits	477	Shared Neighborhood Hits	41
SwissProt Accessions	Q04727, Q5T1Y2, Q9BZ07, Q9BZ08, Q9BZ09, Q9NSL3, Q9ULF9	Gene names	TLE4, KIAA1261
Domain Architecture
Description	Transducin-like enhancer protein 4.

TLE4_MOUSE
θ value	5.27518 (rank : 313)	NC score	0.011291 (rank : 659)
Query Neighborhood Hits	376	Target Neighborhood Hits	482	Shared Neighborhood Hits	41
SwissProt Accessions	Q62441, Q9JKQ9	Gene names	Tle4, Grg4
Domain Architecture
Description	Transducin-like enhancer protein 4 (Groucho-related protein 4) (Grg- 4).

ZF106_MOUSE
θ value	5.27518 (rank : 314)	NC score	0.008996 (rank : 670)
Query Neighborhood Hits	376	Target Neighborhood Hits	472	Shared Neighborhood Hits	26
SwissProt Accessions	O88466, O55185, O88465, O88467, Q792M1, Q792P4, Q8CDZ8, Q8R3I4, Q9ESU3	Gene names	Zfp106, H3a, Sh3bp3, Sirm, Znf474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 (Zfp-106) (Zinc finger protein 474) (H3a minor histocompatibility antigen) (Son of insulin receptor mutant).

ZFHX2_HUMAN
θ value	5.27518 (rank : 315)	NC score	0.028151 (rank : 585)
Query Neighborhood Hits	376	Target Neighborhood Hits	1178	Shared Neighborhood Hits	93
SwissProt Accessions	Q9C0A1	Gene names	ZFHX2, KIAA1762
Domain Architecture
Description	Zinc finger homeobox protein 2.

BAT2_HUMAN
θ value	6.88961 (rank : 316)	NC score	0.139007 (rank : 84)
Query Neighborhood Hits	376	Target Neighborhood Hits	931	Shared Neighborhood Hits	181
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BAZ2A_HUMAN
θ value	6.88961 (rank : 317)	NC score	0.043075 (rank : 528)
Query Neighborhood Hits	376	Target Neighborhood Hits	780	Shared Neighborhood Hits	94
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

BMP6_MOUSE
θ value	6.88961 (rank : 318)	NC score	0.001370 (rank : 693)
Query Neighborhood Hits	376	Target Neighborhood Hits	84	Shared Neighborhood Hits	7
SwissProt Accessions	P20722	Gene names	Bmp6, Bmp-6, Vgr1
Domain Architecture
Description	Bone morphogenetic protein 6 precursor (BMP-6) (VG-1-related protein) (VGR-1).

CAC1B_MOUSE
θ value	6.88961 (rank : 319)	NC score	0.015045 (rank : 640)
Query Neighborhood Hits	376	Target Neighborhood Hits	351	Shared Neighborhood Hits	45
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CCDC6_HUMAN
θ value	6.88961 (rank : 320)	NC score	0.019018 (rank : 628)
Query Neighborhood Hits	376	Target Neighborhood Hits	723	Shared Neighborhood Hits	48
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

CD248_MOUSE
θ value	6.88961 (rank : 321)	NC score	0.041200 (rank : 535)
Query Neighborhood Hits	376	Target Neighborhood Hits	578	Shared Neighborhood Hits	67
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CSPG5_MOUSE
θ value	6.88961 (rank : 322)	NC score	0.030145 (rank : 575)
Query Neighborhood Hits	376	Target Neighborhood Hits	211	Shared Neighborhood Hits	30
SwissProt Accessions	Q71M36, Q71M37, Q7TNT8, Q8BPJ5, Q9QY32	Gene names	Cspg5, Caleb, Ngc
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

CTGE6_HUMAN
θ value	6.88961 (rank : 323)	NC score	0.018578 (rank : 630)
Query Neighborhood Hits	376	Target Neighborhood Hits	650	Shared Neighborhood Hits	43
SwissProt Accessions	Q86UF2	Gene names	CTAGE6
Domain Architecture	No domain graphic available
Description	Protein cTAGE-6 (cTAGE family member 6).

DOCK3_HUMAN
θ value	6.88961 (rank : 324)	NC score	0.022113 (rank : 613)
Query Neighborhood Hits	376	Target Neighborhood Hits	87	Shared Neighborhood Hits	17
SwissProt Accessions	Q8IZD9, O15017	Gene names	DOCK3, KIAA0299, MOCA
Domain Architecture
Description	Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP protein).

DOCK3_MOUSE
θ value	6.88961 (rank : 325)	NC score	0.022406 (rank : 610)
Query Neighborhood Hits	376	Target Neighborhood Hits	93	Shared Neighborhood Hits	17
SwissProt Accessions	Q8CIQ7	Gene names	Dock3, Moca
Domain Architecture
Description	Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP protein).

EPAS1_MOUSE
θ value	6.88961 (rank : 326)	NC score	0.004960 (rank : 683)
Query Neighborhood Hits	376	Target Neighborhood Hits	94	Shared Neighborhood Hits	10
SwissProt Accessions	P97481, O08787, O55046	Gene names	Epas1, Hif2a
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Hypoxia- inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (MHLF) (HIF-related factor) (HRF).

HCLS1_MOUSE
θ value	6.88961 (rank : 327)	NC score	0.089170 (rank : 193)
Query Neighborhood Hits	376	Target Neighborhood Hits	329	Shared Neighborhood Hits	54
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

HXB13_MOUSE
θ value	6.88961 (rank : 328)	NC score	0.000071 (rank : 696)
Query Neighborhood Hits	376	Target Neighborhood Hits	384	Shared Neighborhood Hits	16
SwissProt Accessions	P70321, Q80Y12	Gene names	Hoxb13
Domain Architecture
Description	Homeobox protein Hox-B13.

IWS1_MOUSE
θ value	6.88961 (rank : 329)	NC score	0.040922 (rank : 536)
Query Neighborhood Hits	376	Target Neighborhood Hits	1258	Shared Neighborhood Hits	92
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

K1802_HUMAN
θ value	6.88961 (rank : 330)	NC score	0.094614 (rank : 169)
Query Neighborhood Hits	376	Target Neighborhood Hits	1378	Shared Neighborhood Hits	175
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

KCD18_HUMAN
θ value	6.88961 (rank : 331)	NC score	0.019135 (rank : 626)
Query Neighborhood Hits	376	Target Neighborhood Hits	117	Shared Neighborhood Hits	16
SwissProt Accessions	Q6PI47, Q53T21, Q6NW26, Q6PCD8, Q8N9B7, Q96N73	Gene names	KCTD18
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD18.

MLL2_HUMAN
θ value	6.88961 (rank : 332)	NC score	0.116354 (rank : 119)
Query Neighborhood Hits	376	Target Neighborhood Hits	1788	Shared Neighborhood Hits	221
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MYH9_MOUSE
θ value	6.88961 (rank : 333)	NC score	0.034016 (rank : 555)
Query Neighborhood Hits	376	Target Neighborhood Hits	1829	Shared Neighborhood Hits	72
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

NPAS4_HUMAN
θ value	6.88961 (rank : 334)	NC score	0.025681 (rank : 593)
Query Neighborhood Hits	376	Target Neighborhood Hits	214	Shared Neighborhood Hits	34
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

NTBP1_MOUSE
θ value	6.88961 (rank : 335)	NC score	0.026484 (rank : 590)
Query Neighborhood Hits	376	Target Neighborhood Hits	528	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BRM2, Q8CAA8	Gene names	Scyl1bp1, Ntklbp1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like-binding protein 1 (NTKL-binding protein 1) (NTKL-BP1) (mNTKL-BP1) (SCY1-like 1-binding protein 1) (SCYL1-binding protein 1) (SCYL1-BP1).

P85B_MOUSE
θ value	6.88961 (rank : 336)	NC score	0.084181 (rank : 208)
Query Neighborhood Hits	376	Target Neighborhood Hits	519	Shared Neighborhood Hits	47
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

PAX5_HUMAN
θ value	6.88961 (rank : 337)	NC score	0.013583 (rank : 651)
Query Neighborhood Hits	376	Target Neighborhood Hits	106	Shared Neighborhood Hits	15
SwissProt Accessions	Q02548, O75933	Gene names	PAX5
Domain Architecture
Description	Paired box protein Pax-5 (B-cell-specific transcription factor) (BSAP).

PAX5_MOUSE
θ value	6.88961 (rank : 338)	NC score	0.013675 (rank : 650)
Query Neighborhood Hits	376	Target Neighborhood Hits	106	Shared Neighborhood Hits	16
SwissProt Accessions	Q02650	Gene names	Pax5, Pax-5
Domain Architecture
Description	Paired box protein Pax-5 (B-cell-specific transcription factor) (BSAP).

PHF20_MOUSE
θ value	6.88961 (rank : 339)	NC score	0.023455 (rank : 603)
Query Neighborhood Hits	376	Target Neighborhood Hits	513	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

PIGQ_HUMAN
θ value	6.88961 (rank : 340)	NC score	0.012235 (rank : 655)
Query Neighborhood Hits	376	Target Neighborhood Hits	84	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BRB3, O14927, Q96G00, Q96S22, Q9UJH4	Gene names	PIGQ, GPI1
Domain Architecture
Description	Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q (EC 2.4.1.198) (Phosphatidylinositol-glycan biosynthesis class Q protein) (PIG-Q) (N-acetylglucosamyl transferase component GPI1).

PK3CB_HUMAN
θ value	6.88961 (rank : 341)	NC score	0.002191 (rank : 691)
Query Neighborhood Hits	376	Target Neighborhood Hits	43	Shared Neighborhood Hits	2
SwissProt Accessions	P42338	Gene names	PIK3CB
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit beta) (PtdIns-3-kinase p110) (PI3K) (PI3Kbeta).

PRDM2_HUMAN
θ value	6.88961 (rank : 342)	NC score	0.031800 (rank : 568)
Query Neighborhood Hits	376	Target Neighborhood Hits	1135	Shared Neighborhood Hits	125
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

RASF7_MOUSE
θ value	6.88961 (rank : 343)	NC score	0.027405 (rank : 589)
Query Neighborhood Hits	376	Target Neighborhood Hits	136	Shared Neighborhood Hits	17
SwissProt Accessions	Q9DD19	Gene names	Rassf7
Domain Architecture
Description	Ras association domain-containing protein 7.

RX_MOUSE
θ value	6.88961 (rank : 344)	NC score	0.006031 (rank : 679)
Query Neighborhood Hits	376	Target Neighborhood Hits	429	Shared Neighborhood Hits	30
SwissProt Accessions	O35602, O08748	Gene names	Rax, Rx
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

SASH1_HUMAN
θ value	6.88961 (rank : 345)	NC score	0.035978 (rank : 549)
Query Neighborhood Hits	376	Target Neighborhood Hits	292	Shared Neighborhood Hits	65
SwissProt Accessions	O94885, Q8TAI0, Q9H7R7	Gene names	SASH1, KIAA0790, PEPE1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat- containing protein).

SATB1_HUMAN
θ value	6.88961 (rank : 346)	NC score	0.011053 (rank : 663)
Query Neighborhood Hits	376	Target Neighborhood Hits	130	Shared Neighborhood Hits	16
SwissProt Accessions	Q01826	Gene names	SATB1
Domain Architecture
Description	DNA-binding protein SATB1 (Special AT-rich sequence-binding protein 1).

SATB1_MOUSE
θ value	6.88961 (rank : 347)	NC score	0.011258 (rank : 661)
Query Neighborhood Hits	376	Target Neighborhood Hits	130	Shared Neighborhood Hits	17
SwissProt Accessions	Q60611	Gene names	Satb1
Domain Architecture
Description	DNA-binding protein SATB1 (Special AT-rich sequence-binding protein 1).

SOX30_MOUSE
θ value	6.88961 (rank : 348)	NC score	0.030311 (rank : 574)
Query Neighborhood Hits	376	Target Neighborhood Hits	374	Shared Neighborhood Hits	55
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

STON2_HUMAN
θ value	6.88961 (rank : 349)	NC score	0.014881 (rank : 642)
Query Neighborhood Hits	376	Target Neighborhood Hits	115	Shared Neighborhood Hits	15
SwissProt Accessions	Q8WXE9, Q6NT47, Q96RI7, Q96RU6	Gene names	STON2, STN2, STNB
Domain Architecture
Description	Stonin-2 (Stoned B).

SYNG_HUMAN
θ value	6.88961 (rank : 350)	NC score	0.017442 (rank : 635)
Query Neighborhood Hits	376	Target Neighborhood Hits	160	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UMZ2, Q6ZT17	Gene names	AP1GBP1, SYNG
Domain Architecture	No domain graphic available
Description	AP1 subunit gamma-binding protein 1 (Gamma-synergin).

TENS4_MOUSE
θ value	6.88961 (rank : 351)	NC score	0.030043 (rank : 577)
Query Neighborhood Hits	376	Target Neighborhood Hits	225	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BZ33, Q3TCM8, Q7TNR5	Gene names	Tns4
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor.

ACINU_MOUSE
θ value	8.99809 (rank : 352)	NC score	0.053001 (rank : 470)
Query Neighborhood Hits	376	Target Neighborhood Hits	712	Shared Neighborhood Hits	86
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

ANR25_MOUSE
θ value	8.99809 (rank : 353)	NC score	0.017498 (rank : 634)
Query Neighborhood Hits	376	Target Neighborhood Hits	398	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

BAT3_MOUSE
θ value	8.99809 (rank : 354)	NC score	0.093684 (rank : 173)
Query Neighborhood Hits	376	Target Neighborhood Hits	518	Shared Neighborhood Hits	110
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

BSN_HUMAN
θ value	8.99809 (rank : 355)	NC score	0.124361 (rank : 108)
Query Neighborhood Hits	376	Target Neighborhood Hits	1537	Shared Neighborhood Hits	203
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CNOT4_HUMAN
θ value	8.99809 (rank : 356)	NC score	0.013723 (rank : 649)
Query Neighborhood Hits	376	Target Neighborhood Hits	207	Shared Neighborhood Hits	21
SwissProt Accessions	O95628, O95339, O95627, Q8IYM7, Q8NCL0, Q9NPQ1, Q9NZN6	Gene names	CNOT4, NOT4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

CSPG3_HUMAN
θ value	8.99809 (rank : 357)	NC score	0.013983 (rank : 648)
Query Neighborhood Hits	376	Target Neighborhood Hits	676	Shared Neighborhood Hits	58
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

DLG5_HUMAN
θ value	8.99809 (rank : 358)	NC score	0.028510 (rank : 583)
Query Neighborhood Hits	376	Target Neighborhood Hits	1088	Shared Neighborhood Hits	69
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

DNL1_HUMAN
θ value	8.99809 (rank : 359)	NC score	0.033004 (rank : 562)
Query Neighborhood Hits	376	Target Neighborhood Hits	216	Shared Neighborhood Hits	38
SwissProt Accessions	P18858	Gene names	LIG1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

EMSY_HUMAN
θ value	8.99809 (rank : 360)	NC score	0.028199 (rank : 584)
Query Neighborhood Hits	376	Target Neighborhood Hits	296	Shared Neighborhood Hits	35
SwissProt Accessions	Q7Z589, Q4G109, Q8NBU6, Q8TE50, Q9H8I9, Q9NRH0	Gene names	EMSY, C11orf30
Domain Architecture
Description	Protein EMSY.

FA61A_MOUSE
θ value	8.99809 (rank : 361)	NC score	0.010903 (rank : 665)
Query Neighborhood Hits	376	Target Neighborhood Hits	81	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K2F8, Q9CTG8	Gene names	Fam61a
Domain Architecture	No domain graphic available
Description	Protein FAM61A.

GP108_MOUSE
θ value	8.99809 (rank : 362)	NC score	0.008314 (rank : 675)
Query Neighborhood Hits	376	Target Neighborhood Hits	85	Shared Neighborhood Hits	13
SwissProt Accessions	Q91WD0, Q8BXE9, Q925B1	Gene names	Gpr108, Lustr2
Domain Architecture	No domain graphic available
Description	Protein GPR108 precursor (Lung seven transmembrane receptor 2).

HRX_HUMAN
θ value	8.99809 (rank : 363)	NC score	0.067512 (rank : 309)
Query Neighborhood Hits	376	Target Neighborhood Hits	825	Shared Neighborhood Hits	115
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

HXD3_HUMAN
θ value	8.99809 (rank : 364)	NC score	0.004359 (rank : 685)
Query Neighborhood Hits	376	Target Neighborhood Hits	433	Shared Neighborhood Hits	38
SwissProt Accessions	P31249, Q99955, Q9BSC5	Gene names	HOXD3, HOX4A
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4A).

K1210_HUMAN
θ value	8.99809 (rank : 365)	NC score	0.043357 (rank : 527)
Query Neighborhood Hits	376	Target Neighborhood Hits	219	Shared Neighborhood Hits	39
SwissProt Accessions	Q9ULL0, Q5JPN4	Gene names	KIAA1210
Domain Architecture	No domain graphic available
Description	Protein KIAA1210.

MILK2_HUMAN
θ value	8.99809 (rank : 366)	NC score	0.059972 (rank : 378)
Query Neighborhood Hits	376	Target Neighborhood Hits	457	Shared Neighborhood Hits	93
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

MRCKG_HUMAN
θ value	8.99809 (rank : 367)	NC score	0.004857 (rank : 684)
Query Neighborhood Hits	376	Target Neighborhood Hits	1519	Shared Neighborhood Hits	57
SwissProt Accessions	Q6DT37, O00565	Gene names	CDC42BPG
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

NPAS4_MOUSE
θ value	8.99809 (rank : 368)	NC score	0.031284 (rank : 571)
Query Neighborhood Hits	376	Target Neighborhood Hits	245	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

PELP1_MOUSE
θ value	8.99809 (rank : 369)	NC score	0.100082 (rank : 155)
Query Neighborhood Hits	376	Target Neighborhood Hits	709	Shared Neighborhood Hits	135
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

RAPH1_HUMAN
θ value	8.99809 (rank : 370)	NC score	0.147369 (rank : 79)
Query Neighborhood Hits	376	Target Neighborhood Hits	593	Shared Neighborhood Hits	170
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

RXRA_HUMAN
θ value	8.99809 (rank : 371)	NC score	0.000285 (rank : 695)
Query Neighborhood Hits	376	Target Neighborhood Hits	223	Shared Neighborhood Hits	15
SwissProt Accessions	P19793, Q2V504	Gene names	RXRA, NR2B1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

SEM4D_MOUSE
θ value	8.99809 (rank : 372)	NC score	0.003266 (rank : 688)
Query Neighborhood Hits	376	Target Neighborhood Hits	143	Shared Neighborhood Hits	10
SwissProt Accessions	O09126	Gene names	Sema4d, Semacl2, Semaj
Domain Architecture
Description	Semaphorin-4D precursor (Semaphorin J) (Sema J) (Semaphorin C-like 2) (M-Sema G).

SPRR3_HUMAN
θ value	8.99809 (rank : 373)	NC score	0.049813 (rank : 512)
Query Neighborhood Hits	376	Target Neighborhood Hits	102	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UBC9, O75597, Q4ZGI7, Q5T525, Q8NET7, Q9UDG3	Gene names	SPRR3, SPRC
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta) (Esophagin) (22 kDa pancornulin).

SWP70_HUMAN
θ value	8.99809 (rank : 374)	NC score	0.020505 (rank : 623)
Query Neighborhood Hits	376	Target Neighborhood Hits	973	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

TAF9_MOUSE
θ value	8.99809 (rank : 375)	NC score	0.010379 (rank : 668)
Query Neighborhood Hits	376	Target Neighborhood Hits	69	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VI33, Q32P09, Q80XS3, Q9CV61	Gene names	Taf9, Taf2g
Domain Architecture
Description	Transcription initiation factor TFIID subunit 9 (Transcription initiation factor TFIID 31 kDa subunit) (TAFII-31) (TAFII-32) (TAFII32).

TNR4_MOUSE
θ value	8.99809 (rank : 376)	NC score	0.002744 (rank : 689)
Query Neighborhood Hits	376	Target Neighborhood Hits	137	Shared Neighborhood Hits	5
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

3BP2_MOUSE
θ value	θ > 10 (rank : 377)	NC score	0.058802 (rank : 397)
Query Neighborhood Hits	376	Target Neighborhood Hits	142	Shared Neighborhood Hits	33
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

AB1IP_HUMAN
θ value	θ > 10 (rank : 378)	NC score	0.068503 (rank : 295)
Query Neighborhood Hits	376	Target Neighborhood Hits	213	Shared Neighborhood Hits	76
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

AB1IP_MOUSE
θ value	θ > 10 (rank : 379)	NC score	0.054143 (rank : 454)
Query Neighborhood Hits	376	Target Neighborhood Hits	181	Shared Neighborhood Hits	68
SwissProt Accessions	Q8R5A3, O35329, Q8BRU0, Q99KV8	Gene names	Apbb1ip, Prel1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 48).

ABI1_HUMAN
θ value	θ > 10 (rank : 380)	NC score	0.064941 (rank : 323)
Query Neighborhood Hits	376	Target Neighborhood Hits	257	Shared Neighborhood Hits	49
SwissProt Accessions	Q8IZP0, O15147, O76049, O95060, Q5W070, Q5W072, Q8TB63, Q96S81, Q9NXZ9, Q9NYB8	Gene names	ABI1, SSH3BP1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Nap1-binding protein) (Nap1BP) (Abl-binding protein 4) (AblBP4).

ABI1_MOUSE
θ value	θ > 10 (rank : 381)	NC score	0.060417 (rank : 370)
Query Neighborhood Hits	376	Target Neighborhood Hits	246	Shared Neighborhood Hits	38
SwissProt Accessions	Q8CBW3, Q60747, Q91ZM5, Q923I9, Q99KH4	Gene names	Abi1, Ssh3bp1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Ablphilin-1).

ABI2_HUMAN
θ value	θ > 10 (rank : 382)	NC score	0.095380 (rank : 168)
Query Neighborhood Hits	376	Target Neighborhood Hits	350	Shared Neighborhood Hits	84
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

ABI2_MOUSE
θ value	θ > 10 (rank : 383)	NC score	0.069985 (rank : 290)
Query Neighborhood Hits	376	Target Neighborhood Hits	266	Shared Neighborhood Hits	45
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

ABI3_HUMAN
θ value	θ > 10 (rank : 384)	NC score	0.064255 (rank : 330)
Query Neighborhood Hits	376	Target Neighborhood Hits	227	Shared Neighborhood Hits	53
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

ABI3_MOUSE
θ value	θ > 10 (rank : 385)	NC score	0.060740 (rank : 361)
Query Neighborhood Hits	376	Target Neighborhood Hits	227	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

AFF1_HUMAN
θ value	θ > 10 (rank : 386)	NC score	0.068057 (rank : 304)
Query Neighborhood Hits	376	Target Neighborhood Hits	506	Shared Neighborhood Hits	86
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

AFF1_MOUSE
θ value	θ > 10 (rank : 387)	NC score	0.060254 (rank : 375)
Query Neighborhood Hits	376	Target Neighborhood Hits	351	Shared Neighborhood Hits	81
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

ALEX_HUMAN
θ value	θ > 10 (rank : 388)	NC score	0.108007 (rank : 135)
Query Neighborhood Hits	376	Target Neighborhood Hits	361	Shared Neighborhood Hits	103
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

ALEX_MOUSE
θ value	θ > 10 (rank : 389)	NC score	0.083047 (rank : 214)
Query Neighborhood Hits	376	Target Neighborhood Hits	197	Shared Neighborhood Hits	72
SwissProt Accessions	Q6R0H6, Q8BIR3	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

AP180_HUMAN
θ value	θ > 10 (rank : 390)	NC score	0.059951 (rank : 379)
Query Neighborhood Hits	376	Target Neighborhood Hits	183	Shared Neighborhood Hits	56
SwissProt Accessions	O60641, Q5JX13, Q68DL9, Q6P9D3, Q9NTY7	Gene names	SNAP91, KIAA0656
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein).

AP180_MOUSE
θ value	θ > 10 (rank : 391)	NC score	0.061268 (rank : 357)
Query Neighborhood Hits	376	Target Neighborhood Hits	194	Shared Neighborhood Hits	54
SwissProt Accessions	Q61548, Q61547	Gene names	Snap91
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein) (Phosphoprotein F1- 20).

APXL_HUMAN
θ value	θ > 10 (rank : 392)	NC score	0.053076 (rank : 468)
Query Neighborhood Hits	376	Target Neighborhood Hits	553	Shared Neighborhood Hits	77
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

ARHG7_MOUSE
θ value	θ > 10 (rank : 393)	NC score	0.054095 (rank : 455)
Query Neighborhood Hits	376	Target Neighborhood Hits	396	Shared Neighborhood Hits	35
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

ARHGF_HUMAN
θ value	θ > 10 (rank : 394)	NC score	0.050582 (rank : 507)
Query Neighborhood Hits	376	Target Neighborhood Hits	214	Shared Neighborhood Hits	71
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

ARI1A_HUMAN
θ value	θ > 10 (rank : 395)	NC score	0.076554 (rank : 242)
Query Neighborhood Hits	376	Target Neighborhood Hits	787	Shared Neighborhood Hits	132
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

ARI1B_HUMAN
θ value	θ > 10 (rank : 396)	NC score	0.067697 (rank : 306)
Query Neighborhood Hits	376	Target Neighborhood Hits	567	Shared Neighborhood Hits	105
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

ASPP1_HUMAN
θ value	θ > 10 (rank : 397)	NC score	0.073884 (rank : 262)
Query Neighborhood Hits	376	Target Neighborhood Hits	956	Shared Neighborhood Hits	111
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ASPP2_HUMAN
θ value	θ > 10 (rank : 398)	NC score	0.051691 (rank : 491)
Query Neighborhood Hits	376	Target Neighborhood Hits	1156	Shared Neighborhood Hits	98
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

ATCAY_HUMAN
θ value	θ > 10 (rank : 399)	NC score	0.060201 (rank : 376)
Query Neighborhood Hits	376	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	Q86WG3, Q8NAQ2, Q8TAQ3, Q96HC6, Q96JF5	Gene names	ATCAY, KIAA1872
Domain Architecture
Description	Caytaxin (Ataxia Cayman type protein) (BNIP-H).

ATCAY_MOUSE
θ value	θ > 10 (rank : 400)	NC score	0.060719 (rank : 362)
Query Neighborhood Hits	376	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BHE3, Q3TR94	Gene names	Atcay
Domain Architecture
Description	Caytaxin.

ATN1_HUMAN
θ value	θ > 10 (rank : 401)	NC score	0.122392 (rank : 112)
Query Neighborhood Hits	376	Target Neighborhood Hits	676	Shared Neighborhood Hits	147
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

ATX2L_HUMAN
θ value	θ > 10 (rank : 402)	NC score	0.065571 (rank : 320)
Query Neighborhood Hits	376	Target Neighborhood Hits	443	Shared Neighborhood Hits	89
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

ATX2_HUMAN
θ value	θ > 10 (rank : 403)	NC score	0.060627 (rank : 364)
Query Neighborhood Hits	376	Target Neighborhood Hits	375	Shared Neighborhood Hits	81
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

ATX2_MOUSE
θ value	θ > 10 (rank : 404)	NC score	0.060320 (rank : 374)
Query Neighborhood Hits	376	Target Neighborhood Hits	445	Shared Neighborhood Hits	88
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

AUTS2_HUMAN
θ value	θ > 10 (rank : 405)	NC score	0.058039 (rank : 406)
Query Neighborhood Hits	376	Target Neighborhood Hits	342	Shared Neighborhood Hits	84
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

BASP_HUMAN
θ value	θ > 10 (rank : 406)	NC score	0.122485 (rank : 111)
Query Neighborhood Hits	376	Target Neighborhood Hits	321	Shared Neighborhood Hits	84
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BASP_MOUSE
θ value	θ > 10 (rank : 407)	NC score	0.128981 (rank : 98)
Query Neighborhood Hits	376	Target Neighborhood Hits	260	Shared Neighborhood Hits	67
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BAT2_MOUSE
θ value	θ > 10 (rank : 408)	NC score	0.108533 (rank : 134)
Query Neighborhood Hits	376	Target Neighborhood Hits	947	Shared Neighborhood Hits	171
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BAT3_HUMAN
θ value	θ > 10 (rank : 409)	NC score	0.070574 (rank : 285)
Query Neighborhood Hits	376	Target Neighborhood Hits	490	Shared Neighborhood Hits	89
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

BCAR1_HUMAN
θ value	θ > 10 (rank : 410)	NC score	0.059300 (rank : 389)
Query Neighborhood Hits	376	Target Neighborhood Hits	554	Shared Neighborhood Hits	80
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

BCAR1_MOUSE
θ value	θ > 10 (rank : 411)	NC score	0.066756 (rank : 314)
Query Neighborhood Hits	376	Target Neighborhood Hits	438	Shared Neighborhood Hits	77
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

BCL9_MOUSE
θ value	θ > 10 (rank : 412)	NC score	0.086487 (rank : 201)
Query Neighborhood Hits	376	Target Neighborhood Hits	770	Shared Neighborhood Hits	128
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

BNIP2_HUMAN
θ value	θ > 10 (rank : 413)	NC score	0.063853 (rank : 334)
Query Neighborhood Hits	376	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q12982	Gene names	BNIP2, NIP2
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 2.

BNIP2_MOUSE
θ value	θ > 10 (rank : 414)	NC score	0.063741 (rank : 336)
Query Neighborhood Hits	376	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	O54940	Gene names	Bnip2, Nip2l
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 2.

BNIPL_HUMAN
θ value	θ > 10 (rank : 415)	NC score	0.059882 (rank : 380)
Query Neighborhood Hits	376	Target Neighborhood Hits	40	Shared Neighborhood Hits	7
SwissProt Accessions	Q7Z465, Q6DK43, Q8TCY7, Q8WYG2	Gene names	BNIPL
Domain Architecture	No domain graphic available
Description	Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein.

BNIPL_MOUSE
θ value	θ > 10 (rank : 416)	NC score	0.058965 (rank : 394)
Query Neighborhood Hits	376	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q99JU7, Q923E3	Gene names	Bnipl
Domain Architecture	No domain graphic available
Description	Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein.

BRD4_HUMAN
θ value	θ > 10 (rank : 417)	NC score	0.076761 (rank : 240)
Query Neighborhood Hits	376	Target Neighborhood Hits	851	Shared Neighborhood Hits	151
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

BRD4_MOUSE
θ value	θ > 10 (rank : 418)	NC score	0.087393 (rank : 198)
Query Neighborhood Hits	376	Target Neighborhood Hits	845	Shared Neighborhood Hits	159
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

CBP_HUMAN
θ value	θ > 10 (rank : 419)	NC score	0.090049 (rank : 190)
Query Neighborhood Hits	376	Target Neighborhood Hits	941	Shared Neighborhood Hits	181
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CBP_MOUSE
θ value	θ > 10 (rank : 420)	NC score	0.083649 (rank : 211)
Query Neighborhood Hits	376	Target Neighborhood Hits	1051	Shared Neighborhood Hits	177
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CCD1A_HUMAN
θ value	θ > 10 (rank : 421)	NC score	0.050614 (rank : 506)
Query Neighborhood Hits	376	Target Neighborhood Hits	123	Shared Neighborhood Hits	40
SwissProt Accessions	Q6P1N0, Q7Z435, Q86XV0, Q8NF89, Q9H603, Q9NXI1	Gene names	CC2D1A
Domain Architecture	No domain graphic available
Description	Coiled-coil and C2 domain-containing protein 1A (Five repressor element under dual repression-binding protein 1) (FRE under dual repression-binding protein 1) (Freud-1) (Putative NF-kappa-B- activating protein 023N).

CCNK_MOUSE
θ value	θ > 10 (rank : 422)	NC score	0.100330 (rank : 154)
Query Neighborhood Hits	376	Target Neighborhood Hits	350	Shared Neighborhood Hits	114
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

CD2AP_HUMAN
θ value	θ > 10 (rank : 423)	NC score	0.070553 (rank : 286)
Query Neighborhood Hits	376	Target Neighborhood Hits	315	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

CD2AP_MOUSE
θ value	θ > 10 (rank : 424)	NC score	0.068335 (rank : 300)
Query Neighborhood Hits	376	Target Neighborhood Hits	336	Shared Neighborhood Hits	59
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

CDN1C_HUMAN
θ value	θ > 10 (rank : 425)	NC score	0.103406 (rank : 147)
Query Neighborhood Hits	376	Target Neighborhood Hits	168	Shared Neighborhood Hits	75
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

CENB1_HUMAN
θ value	θ > 10 (rank : 426)	NC score	0.067733 (rank : 305)
Query Neighborhood Hits	376	Target Neighborhood Hits	383	Shared Neighborhood Hits	26
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

CENB2_HUMAN
θ value	θ > 10 (rank : 427)	NC score	0.074156 (rank : 261)
Query Neighborhood Hits	376	Target Neighborhood Hits	425	Shared Neighborhood Hits	30
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

CENB5_HUMAN
θ value	θ > 10 (rank : 428)	NC score	0.068085 (rank : 303)
Query Neighborhood Hits	376	Target Neighborhood Hits	395	Shared Neighborhood Hits	22
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

CEND_HUMAN
θ value	θ > 10 (rank : 429)	NC score	0.056263 (rank : 426)
Query Neighborhood Hits	376	Target Neighborhood Hits	84	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N111, Q9NYM6	Gene names	CEND1, BM88
Domain Architecture	No domain graphic available
Description	Cell cycle exit and neuronal differentiation protein 1 (BM88 antigen).

CENG1_HUMAN
θ value	θ > 10 (rank : 430)	NC score	0.056157 (rank : 429)
Query Neighborhood Hits	376	Target Neighborhood Hits	544	Shared Neighborhood Hits	69
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

CENG1_MOUSE
θ value	θ > 10 (rank : 431)	NC score	0.059538 (rank : 385)
Query Neighborhood Hits	376	Target Neighborhood Hits	531	Shared Neighborhood Hits	66
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

CG1_HUMAN
θ value	θ > 10 (rank : 432)	NC score	0.053209 (rank : 464)
Query Neighborhood Hits	376	Target Neighborhood Hits	222	Shared Neighborhood Hits	53
SwissProt Accessions	Q13495	Gene names	CXorf6, CG1
Domain Architecture	No domain graphic available
Description	CG1 protein (F18).

CIC_MOUSE
θ value	θ > 10 (rank : 433)	NC score	0.093909 (rank : 170)
Query Neighborhood Hits	376	Target Neighborhood Hits	742	Shared Neighborhood Hits	161
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CIP4_HUMAN
θ value	θ > 10 (rank : 434)	NC score	0.064718 (rank : 326)
Query Neighborhood Hits	376	Target Neighborhood Hits	374	Shared Neighborhood Hits	29
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

CITE4_HUMAN
θ value	θ > 10 (rank : 435)	NC score	0.051459 (rank : 497)
Query Neighborhood Hits	376	Target Neighborhood Hits	67	Shared Neighborhood Hits	29
SwissProt Accessions	Q96RK1	Gene names	CITED4, MRG2
Domain Architecture	No domain graphic available
Description	Cbp/p300-interacting transactivator 4 (MSG1-related protein 2) (MRG- 2).

CIZ1_HUMAN
θ value	θ > 10 (rank : 436)	NC score	0.058881 (rank : 396)
Query Neighborhood Hits	376	Target Neighborhood Hits	359	Shared Neighborhood Hits	58
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

CJ078_MOUSE
θ value	θ > 10 (rank : 437)	NC score	0.129426 (rank : 97)
Query Neighborhood Hits	376	Target Neighborhood Hits	559	Shared Neighborhood Hits	123
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

CK024_HUMAN
θ value	θ > 10 (rank : 438)	NC score	0.104629 (rank : 143)
Query Neighborhood Hits	376	Target Neighborhood Hits	408	Shared Neighborhood Hits	89
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

CN032_HUMAN
θ value	θ > 10 (rank : 439)	NC score	0.128777 (rank : 99)
Query Neighborhood Hits	376	Target Neighborhood Hits	267	Shared Neighborhood Hits	99
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

CN032_MOUSE
θ value	θ > 10 (rank : 440)	NC score	0.124047 (rank : 109)
Query Neighborhood Hits	376	Target Neighborhood Hits	233	Shared Neighborhood Hits	82
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

CN155_HUMAN
θ value	θ > 10 (rank : 441)	NC score	0.130496 (rank : 95)
Query Neighborhood Hits	376	Target Neighborhood Hits	385	Shared Neighborhood Hits	104
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

CNOT3_HUMAN
θ value	θ > 10 (rank : 442)	NC score	0.077968 (rank : 236)
Query Neighborhood Hits	376	Target Neighborhood Hits	425	Shared Neighborhood Hits	88
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CNOT3_MOUSE
θ value	θ > 10 (rank : 443)	NC score	0.068431 (rank : 297)
Query Neighborhood Hits	376	Target Neighborhood Hits	504	Shared Neighborhood Hits	97
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CO039_HUMAN
θ value	θ > 10 (rank : 444)	NC score	0.069840 (rank : 291)
Query Neighborhood Hits	376	Target Neighborhood Hits	264	Shared Neighborhood Hits	77
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

CO039_MOUSE
θ value	θ > 10 (rank : 445)	NC score	0.064033 (rank : 332)
Query Neighborhood Hits	376	Target Neighborhood Hits	445	Shared Neighborhood Hits	92
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

CPSF6_HUMAN
θ value	θ > 10 (rank : 446)	NC score	0.107849 (rank : 136)
Query Neighborhood Hits	376	Target Neighborhood Hits	359	Shared Neighborhood Hits	93
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

CPSF6_MOUSE
θ value	θ > 10 (rank : 447)	NC score	0.109425 (rank : 133)
Query Neighborhood Hits	376	Target Neighborhood Hits	356	Shared Neighborhood Hits	95
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

CRKL_HUMAN
θ value	θ > 10 (rank : 448)	NC score	0.056271 (rank : 425)
Query Neighborhood Hits	376	Target Neighborhood Hits	313	Shared Neighborhood Hits	37
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

CRKL_MOUSE
θ value	θ > 10 (rank : 449)	NC score	0.051708 (rank : 490)
Query Neighborhood Hits	376	Target Neighborhood Hits	307	Shared Neighborhood Hits	35
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

CRTC1_HUMAN
θ value	θ > 10 (rank : 450)	NC score	0.073087 (rank : 268)
Query Neighborhood Hits	376	Target Neighborhood Hits	319	Shared Neighborhood Hits	88
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

CRTC1_MOUSE
θ value	θ > 10 (rank : 451)	NC score	0.050220 (rank : 510)
Query Neighborhood Hits	376	Target Neighborhood Hits	230	Shared Neighborhood Hits	59
SwissProt Accessions	Q68ED7, Q6ZQ85	Gene names	Crtc1, Kiaa0616, Mect1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1 homolog).

CS007_HUMAN
θ value	θ > 10 (rank : 452)	NC score	0.061361 (rank : 356)
Query Neighborhood Hits	376	Target Neighborhood Hits	401	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

CS007_MOUSE
θ value	θ > 10 (rank : 453)	NC score	0.070487 (rank : 287)
Query Neighborhood Hits	376	Target Neighborhood Hits	464	Shared Neighborhood Hits	96
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

CS016_HUMAN
θ value	θ > 10 (rank : 454)	NC score	0.139216 (rank : 83)
Query Neighborhood Hits	376	Target Neighborhood Hits	310	Shared Neighborhood Hits	116
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

CSKI2_HUMAN
θ value	θ > 10 (rank : 455)	NC score	0.065899 (rank : 318)
Query Neighborhood Hits	376	Target Neighborhood Hits	747	Shared Neighborhood Hits	135
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CSKI2_MOUSE
θ value	θ > 10 (rank : 456)	NC score	0.059269 (rank : 390)
Query Neighborhood Hits	376	Target Neighborhood Hits	812	Shared Neighborhood Hits	121
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CT151_HUMAN
θ value	θ > 10 (rank : 457)	NC score	0.052515 (rank : 479)
Query Neighborhood Hits	376	Target Neighborhood Hits	382	Shared Neighborhood Hits	69
SwissProt Accessions	Q8NC74, Q8N4Z9, Q9BR75, Q9H0Y9	Gene names	C20orf151
Domain Architecture
Description	Uncharacterized protein C20orf151.

DAPP1_HUMAN
θ value	θ > 10 (rank : 458)	NC score	0.055441 (rank : 436)
Query Neighborhood Hits	376	Target Neighborhood Hits	227	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DAPP1_MOUSE
θ value	θ > 10 (rank : 459)	NC score	0.056679 (rank : 419)
Query Neighborhood Hits	376	Target Neighborhood Hits	225	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DDEF1_MOUSE
θ value	θ > 10 (rank : 460)	NC score	0.072234 (rank : 275)
Query Neighborhood Hits	376	Target Neighborhood Hits	592	Shared Neighborhood Hits	76
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

DDEF2_HUMAN
θ value	θ > 10 (rank : 461)	NC score	0.078960 (rank : 227)
Query Neighborhood Hits	376	Target Neighborhood Hits	599	Shared Neighborhood Hits	91
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
θ value	θ > 10 (rank : 462)	NC score	0.078320 (rank : 234)
Query Neighborhood Hits	376	Target Neighborhood Hits	625	Shared Neighborhood Hits	89
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDFL1_HUMAN
θ value	θ > 10 (rank : 463)	NC score	0.051604 (rank : 492)
Query Neighborhood Hits	376	Target Neighborhood Hits	353	Shared Neighborhood Hits	31
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

DGKK_HUMAN
θ value	θ > 10 (rank : 464)	NC score	0.090843 (rank : 183)
Query Neighborhood Hits	376	Target Neighborhood Hits	378	Shared Neighborhood Hits	107
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

DIAP1_HUMAN
θ value	θ > 10 (rank : 465)	NC score	0.064891 (rank : 324)
Query Neighborhood Hits	376	Target Neighborhood Hits	784	Shared Neighborhood Hits	123
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

DIAP1_MOUSE
θ value	θ > 10 (rank : 466)	NC score	0.058707 (rank : 400)
Query Neighborhood Hits	376	Target Neighborhood Hits	839	Shared Neighborhood Hits	108
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

DNMBP_HUMAN
θ value	θ > 10 (rank : 467)	NC score	0.062790 (rank : 346)
Query Neighborhood Hits	376	Target Neighborhood Hits	413	Shared Neighborhood Hits	51
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

DNMBP_MOUSE
θ value	θ > 10 (rank : 468)	NC score	0.063596 (rank : 337)
Query Neighborhood Hits	376	Target Neighborhood Hits	435	Shared Neighborhood Hits	63
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

DOT1L_HUMAN
θ value	θ > 10 (rank : 469)	NC score	0.069386 (rank : 292)
Query Neighborhood Hits	376	Target Neighborhood Hits	660	Shared Neighborhood Hits	104
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

EFS_HUMAN
θ value	θ > 10 (rank : 470)	NC score	0.079127 (rank : 226)
Query Neighborhood Hits	376	Target Neighborhood Hits	348	Shared Neighborhood Hits	70
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

EFS_MOUSE
θ value	θ > 10 (rank : 471)	NC score	0.061646 (rank : 355)
Query Neighborhood Hits	376	Target Neighborhood Hits	389	Shared Neighborhood Hits	78
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

ENAH_HUMAN
θ value	θ > 10 (rank : 472)	NC score	0.059840 (rank : 381)
Query Neighborhood Hits	376	Target Neighborhood Hits	784	Shared Neighborhood Hits	118
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

ENAH_MOUSE
θ value	θ > 10 (rank : 473)	NC score	0.131883 (rank : 93)
Query Neighborhood Hits	376	Target Neighborhood Hits	919	Shared Neighborhood Hits	183
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

ENL_HUMAN
θ value	θ > 10 (rank : 474)	NC score	0.063549 (rank : 339)
Query Neighborhood Hits	376	Target Neighborhood Hits	305	Shared Neighborhood Hits	53
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

EP300_HUMAN
θ value	θ > 10 (rank : 475)	NC score	0.081824 (rank : 220)
Query Neighborhood Hits	376	Target Neighborhood Hits	821	Shared Neighborhood Hits	148
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

EPN1_HUMAN
θ value	θ > 10 (rank : 476)	NC score	0.060815 (rank : 360)
Query Neighborhood Hits	376	Target Neighborhood Hits	206	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Y6I3, Q86ST3, Q9HA18	Gene names	EPN1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (EH domain-binding mitotic phosphoprotein).

EPN1_MOUSE
θ value	θ > 10 (rank : 477)	NC score	0.058338 (rank : 403)
Query Neighborhood Hits	376	Target Neighborhood Hits	240	Shared Neighborhood Hits	70
SwissProt Accessions	Q80VP1, O70446	Gene names	Epn1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (Intersectin-EH-binding protein 1) (Ibp1).

FA47A_HUMAN
θ value	θ > 10 (rank : 478)	NC score	0.054818 (rank : 447)
Query Neighborhood Hits	376	Target Neighborhood Hits	451	Shared Neighborhood Hits	73
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

FMN1A_MOUSE
θ value	θ > 10 (rank : 479)	NC score	0.065778 (rank : 319)
Query Neighborhood Hits	376	Target Neighborhood Hits	423	Shared Neighborhood Hits	111
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

FMN1B_MOUSE
θ value	θ > 10 (rank : 480)	NC score	0.068578 (rank : 294)
Query Neighborhood Hits	376	Target Neighborhood Hits	447	Shared Neighborhood Hits	114
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

FMN2_HUMAN
θ value	θ > 10 (rank : 481)	NC score	0.089112 (rank : 194)
Query Neighborhood Hits	376	Target Neighborhood Hits	484	Shared Neighborhood Hits	114
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

FMNL_HUMAN
θ value	θ > 10 (rank : 482)	NC score	0.093717 (rank : 172)
Query Neighborhood Hits	376	Target Neighborhood Hits	529	Shared Neighborhood Hits	139
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

FMNL_MOUSE
θ value	θ > 10 (rank : 483)	NC score	0.060413 (rank : 371)
Query Neighborhood Hits	376	Target Neighborhood Hits	428	Shared Neighborhood Hits	107
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

GGN_HUMAN
θ value	θ > 10 (rank : 484)	NC score	0.134091 (rank : 88)
Query Neighborhood Hits	376	Target Neighborhood Hits	269	Shared Neighborhood Hits	106
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GGN_MOUSE
θ value	θ > 10 (rank : 485)	NC score	0.127912 (rank : 100)
Query Neighborhood Hits	376	Target Neighborhood Hits	311	Shared Neighborhood Hits	119
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GRAP2_HUMAN
θ value	θ > 10 (rank : 486)	NC score	0.062358 (rank : 352)
Query Neighborhood Hits	376	Target Neighborhood Hits	304	Shared Neighborhood Hits	38
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

GRAP2_MOUSE
θ value	θ > 10 (rank : 487)	NC score	0.059426 (rank : 388)
Query Neighborhood Hits	376	Target Neighborhood Hits	297	Shared Neighborhood Hits	36
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

GRAP_HUMAN
θ value	θ > 10 (rank : 488)	NC score	0.072349 (rank : 274)
Query Neighborhood Hits	376	Target Neighborhood Hits	307	Shared Neighborhood Hits	37
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

GRAP_MOUSE
θ value	θ > 10 (rank : 489)	NC score	0.070950 (rank : 283)
Query Neighborhood Hits	376	Target Neighborhood Hits	309	Shared Neighborhood Hits	39
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

GRB2_HUMAN
θ value	θ > 10 (rank : 490)	NC score	0.071936 (rank : 278)
Query Neighborhood Hits	376	Target Neighborhood Hits	310	Shared Neighborhood Hits	34
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
θ value	θ > 10 (rank : 491)	NC score	0.071915 (rank : 280)
Query Neighborhood Hits	376	Target Neighborhood Hits	312	Shared Neighborhood Hits	34
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

GRIN1_MOUSE
θ value	θ > 10 (rank : 492)	NC score	0.080476 (rank : 224)
Query Neighborhood Hits	376	Target Neighborhood Hits	337	Shared Neighborhood Hits	82
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

GRP3_HUMAN
θ value	θ > 10 (rank : 493)	NC score	0.075117 (rank : 249)
Query Neighborhood Hits	376	Target Neighborhood Hits	131	Shared Neighborhood Hits	14
SwissProt Accessions	Q8IV61, O94931	Gene names	RASGRP3, GRP3, KIAA0846
Domain Architecture
Description	RAS guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1).

GSCR1_HUMAN
θ value	θ > 10 (rank : 494)	NC score	0.169508 (rank : 68)
Query Neighborhood Hits	376	Target Neighborhood Hits	674	Shared Neighborhood Hits	173
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

HCLS1_HUMAN
θ value	θ > 10 (rank : 495)	NC score	0.087278 (rank : 199)
Query Neighborhood Hits	376	Target Neighborhood Hits	358	Shared Neighborhood Hits	61
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

IASPP_HUMAN
θ value	θ > 10 (rank : 496)	NC score	0.088910 (rank : 195)
Query Neighborhood Hits	376	Target Neighborhood Hits	688	Shared Neighborhood Hits	109
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

IF35_HUMAN
θ value	θ > 10 (rank : 497)	NC score	0.054411 (rank : 450)
Query Neighborhood Hits	376	Target Neighborhood Hits	130	Shared Neighborhood Hits	56
SwissProt Accessions	O00303, Q8N978	Gene names	EIF3S5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

IF35_MOUSE
θ value	θ > 10 (rank : 498)	NC score	0.074905 (rank : 251)
Query Neighborhood Hits	376	Target Neighborhood Hits	210	Shared Neighborhood Hits	80
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

IL3RB_HUMAN
θ value	θ > 10 (rank : 499)	NC score	0.058572 (rank : 401)
Query Neighborhood Hits	376	Target Neighborhood Hits	163	Shared Neighborhood Hits	40
SwissProt Accessions	P32927	Gene names	CSF2RB, IL3RB, IL5RB
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen) (CDw131).

INP5E_HUMAN
θ value	θ > 10 (rank : 500)	NC score	0.056640 (rank : 420)
Query Neighborhood Hits	376	Target Neighborhood Hits	201	Shared Neighborhood Hits	39
SwissProt Accessions	Q9NRR6, Q15734	Gene names	INPP5E
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

IRS2_HUMAN
θ value	θ > 10 (rank : 501)	NC score	0.059484 (rank : 387)
Query Neighborhood Hits	376	Target Neighborhood Hits	262	Shared Neighborhood Hits	83
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

ITSN2_HUMAN
θ value	θ > 10 (rank : 502)	NC score	0.056968 (rank : 417)
Query Neighborhood Hits	376	Target Neighborhood Hits	1173	Shared Neighborhood Hits	70
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

ITSN2_MOUSE
θ value	θ > 10 (rank : 503)	NC score	0.055035 (rank : 443)
Query Neighborhood Hits	376	Target Neighborhood Hits	1371	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

K0310_HUMAN
θ value	θ > 10 (rank : 504)	NC score	0.064600 (rank : 327)
Query Neighborhood Hits	376	Target Neighborhood Hits	420	Shared Neighborhood Hits	86
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

K1543_MOUSE
θ value	θ > 10 (rank : 505)	NC score	0.089709 (rank : 191)
Query Neighborhood Hits	376	Target Neighborhood Hits	497	Shared Neighborhood Hits	87
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

LAD1_HUMAN
θ value	θ > 10 (rank : 506)	NC score	0.056567 (rank : 422)
Query Neighborhood Hits	376	Target Neighborhood Hits	441	Shared Neighborhood Hits	60
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

LDB3_HUMAN
θ value	θ > 10 (rank : 507)	NC score	0.057752 (rank : 408)
Query Neighborhood Hits	376	Target Neighborhood Hits	497	Shared Neighborhood Hits	109
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

MADCA_HUMAN
θ value	θ > 10 (rank : 508)	NC score	0.085170 (rank : 205)
Query Neighborhood Hits	376	Target Neighborhood Hits	221	Shared Neighborhood Hits	77
SwissProt Accessions	Q13477, O60222, O75867	Gene names	MADCAM1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (hMAdCAM-1).

MAP1B_HUMAN
θ value	θ > 10 (rank : 509)	NC score	0.051366 (rank : 499)
Query Neighborhood Hits	376	Target Neighborhood Hits	903	Shared Neighborhood Hits	86
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

MARCS_HUMAN
θ value	θ > 10 (rank : 510)	NC score	0.105480 (rank : 140)
Query Neighborhood Hits	376	Target Neighborhood Hits	204	Shared Neighborhood Hits	65
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

MARCS_MOUSE
θ value	θ > 10 (rank : 511)	NC score	0.093322 (rank : 174)
Query Neighborhood Hits	376	Target Neighborhood Hits	227	Shared Neighborhood Hits	59
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

MAVS_HUMAN
θ value	θ > 10 (rank : 512)	NC score	0.052779 (rank : 475)
Query Neighborhood Hits	376	Target Neighborhood Hits	271	Shared Neighborhood Hits	59
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

MBD6_HUMAN
θ value	θ > 10 (rank : 513)	NC score	0.151403 (rank : 77)
Query Neighborhood Hits	376	Target Neighborhood Hits	349	Shared Neighborhood Hits	125
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

MILK1_HUMAN
θ value	θ > 10 (rank : 514)	NC score	0.074207 (rank : 258)
Query Neighborhood Hits	376	Target Neighborhood Hits	427	Shared Neighborhood Hits	103
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MINT_HUMAN
θ value	θ > 10 (rank : 515)	NC score	0.073870 (rank : 263)
Query Neighborhood Hits	376	Target Neighborhood Hits	1291	Shared Neighborhood Hits	158
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MISS_MOUSE
θ value	θ > 10 (rank : 516)	NC score	0.063056 (rank : 344)
Query Neighborhood Hits	376	Target Neighborhood Hits	444	Shared Neighborhood Hits	81
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

MLL4_HUMAN
θ value	θ > 10 (rank : 517)	NC score	0.114953 (rank : 120)
Query Neighborhood Hits	376	Target Neighborhood Hits	722	Shared Neighborhood Hits	174
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

MN1_HUMAN
θ value	θ > 10 (rank : 518)	NC score	0.055316 (rank : 438)
Query Neighborhood Hits	376	Target Neighborhood Hits	196	Shared Neighborhood Hits	52
SwissProt Accessions	Q10571	Gene names	MN1
Domain Architecture	No domain graphic available
Description	Probable tumor suppressor protein MN1.

MNT_HUMAN
θ value	θ > 10 (rank : 519)	NC score	0.072058 (rank : 277)
Query Neighborhood Hits	376	Target Neighborhood Hits	496	Shared Neighborhood Hits	108
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MNT_MOUSE
θ value	θ > 10 (rank : 520)	NC score	0.071924 (rank : 279)
Query Neighborhood Hits	376	Target Neighborhood Hits	432	Shared Neighborhood Hits	97
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MUC13_MOUSE
θ value	θ > 10 (rank : 521)	NC score	0.078423 (rank : 232)
Query Neighborhood Hits	376	Target Neighborhood Hits	447	Shared Neighborhood Hits	75
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

MUC1_MOUSE
θ value	θ > 10 (rank : 522)	NC score	0.096388 (rank : 164)
Query Neighborhood Hits	376	Target Neighborhood Hits	388	Shared Neighborhood Hits	65
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

MUC2_HUMAN
θ value	θ > 10 (rank : 523)	NC score	0.110349 (rank : 130)
Query Neighborhood Hits	376	Target Neighborhood Hits	906	Shared Neighborhood Hits	172
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

MUC7_HUMAN
θ value	θ > 10 (rank : 524)	NC score	0.189206 (rank : 64)
Query Neighborhood Hits	376	Target Neighborhood Hits	538	Shared Neighborhood Hits	163
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

MYO10_HUMAN
θ value	θ > 10 (rank : 525)	NC score	0.056228 (rank : 427)
Query Neighborhood Hits	376	Target Neighborhood Hits	920	Shared Neighborhood Hits	60
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

MYO15_HUMAN
θ value	θ > 10 (rank : 526)	NC score	0.066761 (rank : 313)
Query Neighborhood Hits	376	Target Neighborhood Hits	671	Shared Neighborhood Hits	123
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

MYO15_MOUSE
θ value	θ > 10 (rank : 527)	NC score	0.063312 (rank : 342)
Query Neighborhood Hits	376	Target Neighborhood Hits	467	Shared Neighborhood Hits	94
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

MYO1E_HUMAN
θ value	θ > 10 (rank : 528)	NC score	0.054611 (rank : 449)
Query Neighborhood Hits	376	Target Neighborhood Hits	293	Shared Neighborhood Hits	34
SwissProt Accessions	Q12965, Q14778	Gene names	MYO1E, MYO1C
Domain Architecture
Description	Myosin Ie (Myosin Ic).

MYO1F_HUMAN
θ value	θ > 10 (rank : 529)	NC score	0.057890 (rank : 407)
Query Neighborhood Hits	376	Target Neighborhood Hits	275	Shared Neighborhood Hits	40
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

MYO1F_MOUSE
θ value	θ > 10 (rank : 530)	NC score	0.055854 (rank : 430)
Query Neighborhood Hits	376	Target Neighborhood Hits	262	Shared Neighborhood Hits	26
SwissProt Accessions	P70248	Gene names	Myo1f
Domain Architecture
Description	Myosin If.

NCF2_HUMAN
θ value	θ > 10 (rank : 531)	NC score	0.060455 (rank : 369)
Query Neighborhood Hits	376	Target Neighborhood Hits	229	Shared Neighborhood Hits	27
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

NCF4_HUMAN
θ value	θ > 10 (rank : 532)	NC score	0.068421 (rank : 298)
Query Neighborhood Hits	376	Target Neighborhood Hits	161	Shared Neighborhood Hits	18
SwissProt Accessions	Q15080, O60808, Q86U56, Q9BU98, Q9NP45	Gene names	NCF4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

NCF4_MOUSE
θ value	θ > 10 (rank : 533)	NC score	0.071552 (rank : 281)
Query Neighborhood Hits	376	Target Neighborhood Hits	177	Shared Neighborhood Hits	20
SwissProt Accessions	P97369	Gene names	Ncf4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

NCK1_HUMAN
θ value	θ > 10 (rank : 534)	NC score	0.057061 (rank : 415)
Query Neighborhood Hits	376	Target Neighborhood Hits	312	Shared Neighborhood Hits	35
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

NCK2_HUMAN
θ value	θ > 10 (rank : 535)	NC score	0.074193 (rank : 259)
Query Neighborhood Hits	376	Target Neighborhood Hits	310	Shared Neighborhood Hits	39
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

NCOR2_MOUSE
θ value	θ > 10 (rank : 536)	NC score	0.056621 (rank : 421)
Query Neighborhood Hits	376	Target Neighborhood Hits	790	Shared Neighborhood Hits	116
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

NELFA_HUMAN
θ value	θ > 10 (rank : 537)	NC score	0.074512 (rank : 254)
Query Neighborhood Hits	376	Target Neighborhood Hits	161	Shared Neighborhood Hits	75
SwissProt Accessions	Q9H3P2, O95392	Gene names	WHSC2, NELFA
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 protein).

NELFA_MOUSE
θ value	θ > 10 (rank : 538)	NC score	0.075959 (rank : 243)
Query Neighborhood Hits	376	Target Neighborhood Hits	195	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BG30, Q8BVE4, Q8VEI7, Q9CSJ9, Q9Z1V9	Gene names	Whsc2, Nelfa, Whsc2h
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 homolog) (mWHSC2).

NEUM_HUMAN
θ value	θ > 10 (rank : 539)	NC score	0.062535 (rank : 349)
Query Neighborhood Hits	376	Target Neighborhood Hits	132	Shared Neighborhood Hits	35
SwissProt Accessions	P17677	Gene names	GAP43
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (PP46) (Neural phosphoprotein B-50).

NEUM_MOUSE
θ value	θ > 10 (rank : 540)	NC score	0.060370 (rank : 372)
Query Neighborhood Hits	376	Target Neighborhood Hits	149	Shared Neighborhood Hits	32
SwissProt Accessions	P06837	Gene names	Gap43, Basp2
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (Calmodulin-binding protein P-57).

NFH_HUMAN
θ value	θ > 10 (rank : 541)	NC score	0.054937 (rank : 445)
Query Neighborhood Hits	376	Target Neighborhood Hits	1242	Shared Neighborhood Hits	124
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

NOLC1_HUMAN
θ value	θ > 10 (rank : 542)	NC score	0.105799 (rank : 139)
Query Neighborhood Hits	376	Target Neighborhood Hits	452	Shared Neighborhood Hits	76
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

NU214_HUMAN
θ value	θ > 10 (rank : 543)	NC score	0.091002 (rank : 182)
Query Neighborhood Hits	376	Target Neighborhood Hits	657	Shared Neighborhood Hits	108
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

OGFR_MOUSE
θ value	θ > 10 (rank : 544)	NC score	0.053937 (rank : 456)
Query Neighborhood Hits	376	Target Neighborhood Hits	584	Shared Neighborhood Hits	62
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

OSTF1_HUMAN
θ value	θ > 10 (rank : 545)	NC score	0.052087 (rank : 484)
Query Neighborhood Hits	376	Target Neighborhood Hits	466	Shared Neighborhood Hits	31
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

OSTF1_MOUSE
θ value	θ > 10 (rank : 546)	NC score	0.050044 (rank : 511)
Query Neighborhood Hits	376	Target Neighborhood Hits	467	Shared Neighborhood Hits	31
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

P55G_HUMAN
θ value	θ > 10 (rank : 547)	NC score	0.058928 (rank : 395)
Query Neighborhood Hits	376	Target Neighborhood Hits	451	Shared Neighborhood Hits	25
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

P55G_MOUSE
θ value	θ > 10 (rank : 548)	NC score	0.058162 (rank : 404)
Query Neighborhood Hits	376	Target Neighborhood Hits	401	Shared Neighborhood Hits	24
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

PAF49_HUMAN
θ value	θ > 10 (rank : 549)	NC score	0.057580 (rank : 411)
Query Neighborhood Hits	376	Target Neighborhood Hits	169	Shared Neighborhood Hits	33
SwissProt Accessions	O15446, Q32N11, Q7Z5U2, Q9UPF6	Gene names	CD3EAP, ASE1, CAST, PAF49
Domain Architecture	No domain graphic available
Description	RNA polymerase I-associated factor PAF49 (Anti-sense to ERCC-1 protein) (ASE-1) (CD3-epsilon-associated protein) (CD3E-associated protein) (CAST).

PCQAP_HUMAN
θ value	θ > 10 (rank : 550)	NC score	0.090592 (rank : 186)
Query Neighborhood Hits	376	Target Neighborhood Hits	549	Shared Neighborhood Hits	105
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

PCQAP_MOUSE
θ value	θ > 10 (rank : 551)	NC score	0.078653 (rank : 231)
Query Neighborhood Hits	376	Target Neighborhood Hits	506	Shared Neighborhood Hits	103
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

PCTL_HUMAN
θ value	θ > 10 (rank : 552)	NC score	0.074413 (rank : 256)
Query Neighborhood Hits	376	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y365, O60532	Gene names	STARD10, SDCCAG28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28) (Antigen NY-CO-28).

PCTL_MOUSE
θ value	θ > 10 (rank : 553)	NC score	0.075273 (rank : 248)
Query Neighborhood Hits	376	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JMD3	Gene names	Stard10, Pctpl, Sdccag28, Sdccagg28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28 homolog).

PDC6I_HUMAN
θ value	θ > 10 (rank : 554)	NC score	0.063594 (rank : 338)
Query Neighborhood Hits	376	Target Neighborhood Hits	278	Shared Neighborhood Hits	93
SwissProt Accessions	Q8WUM4, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5	Gene names	PDCD6IP, AIP1, ALIX, KIAA1375
Domain Architecture
Description	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95).

PDC6I_MOUSE
θ value	θ > 10 (rank : 555)	NC score	0.056998 (rank : 416)
Query Neighborhood Hits	376	Target Neighborhood Hits	275	Shared Neighborhood Hits	91
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

PDCD7_HUMAN
θ value	θ > 10 (rank : 556)	NC score	0.057735 (rank : 409)
Query Neighborhood Hits	376	Target Neighborhood Hits	255	Shared Neighborhood Hits	62
SwissProt Accessions	Q8N8D1, Q96AK8, Q9Y6D7	Gene names	PDCD7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18) (HES18).

PDZD8_HUMAN
θ value	θ > 10 (rank : 557)	NC score	0.068154 (rank : 302)
Query Neighborhood Hits	376	Target Neighborhood Hits	185	Shared Neighborhood Hits	34
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

PELP1_HUMAN
θ value	θ > 10 (rank : 558)	NC score	0.092454 (rank : 176)
Query Neighborhood Hits	376	Target Neighborhood Hits	596	Shared Neighborhood Hits	112
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

PI5PA_MOUSE
θ value	θ > 10 (rank : 559)	NC score	0.122732 (rank : 110)
Query Neighborhood Hits	376	Target Neighborhood Hits	331	Shared Neighborhood Hits	113
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PKHA1_HUMAN
θ value	θ > 10 (rank : 560)	NC score	0.052823 (rank : 473)
Query Neighborhood Hits	376	Target Neighborhood Hits	127	Shared Neighborhood Hits	16
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA4_HUMAN
θ value	θ > 10 (rank : 561)	NC score	0.059657 (rank : 383)
Query Neighborhood Hits	376	Target Neighborhood Hits	283	Shared Neighborhood Hits	67
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PKHA6_MOUSE
θ value	θ > 10 (rank : 562)	NC score	0.056475 (rank : 423)
Query Neighborhood Hits	376	Target Neighborhood Hits	591	Shared Neighborhood Hits	63
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PO121_HUMAN
θ value	θ > 10 (rank : 563)	NC score	0.100069 (rank : 156)
Query Neighborhood Hits	376	Target Neighborhood Hits	344	Shared Neighborhood Hits	90
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

PPIP1_HUMAN
θ value	θ > 10 (rank : 564)	NC score	0.053094 (rank : 467)
Query Neighborhood Hits	376	Target Neighborhood Hits	389	Shared Neighborhood Hits	38
SwissProt Accessions	O43586, O43585, O95657	Gene names	PSTPIP1, CD2BP1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP).

PPRB_MOUSE
θ value	θ > 10 (rank : 565)	NC score	0.054290 (rank : 452)
Query Neighborhood Hits	376	Target Neighborhood Hits	354	Shared Neighborhood Hits	64
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

PRB3_HUMAN
θ value	θ > 10 (rank : 566)	NC score	0.159628 (rank : 73)
Query Neighborhood Hits	376	Target Neighborhood Hits	318	Shared Neighborhood Hits	108
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

PRB4S_HUMAN
θ value	θ > 10 (rank : 567)	NC score	0.155060 (rank : 74)
Query Neighborhood Hits	376	Target Neighborhood Hits	330	Shared Neighborhood Hits	108
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

PRCC_HUMAN
θ value	θ > 10 (rank : 568)	NC score	0.052294 (rank : 481)
Query Neighborhood Hits	376	Target Neighborhood Hits	109	Shared Neighborhood Hits	38
SwissProt Accessions	Q92733, O00665, O00724	Gene names	PRCC, TPRC
Domain Architecture	No domain graphic available
Description	Proline-rich protein PRCC (Papillary renal cell carcinoma translocation-associated gene protein).

PRG4_HUMAN
θ value	θ > 10 (rank : 569)	NC score	0.161806 (rank : 71)
Query Neighborhood Hits	376	Target Neighborhood Hits	764	Shared Neighborhood Hits	168
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRG4_MOUSE
θ value	θ > 10 (rank : 570)	NC score	0.125615 (rank : 104)
Query Neighborhood Hits	376	Target Neighborhood Hits	624	Shared Neighborhood Hits	138
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRP1_HUMAN
θ value	θ > 10 (rank : 571)	NC score	0.176221 (rank : 65)
Query Neighborhood Hits	376	Target Neighborhood Hits	385	Shared Neighborhood Hits	117
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PRP2_MOUSE
θ value	θ > 10 (rank : 572)	NC score	0.201088 (rank : 63)
Query Neighborhood Hits	376	Target Neighborhood Hits	347	Shared Neighborhood Hits	125
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PRP5_HUMAN
θ value	θ > 10 (rank : 573)	NC score	0.073155 (rank : 266)
Query Neighborhood Hits	376	Target Neighborhood Hits	108	Shared Neighborhood Hits	35
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

PRPC_HUMAN
θ value	θ > 10 (rank : 574)	NC score	0.082581 (rank : 216)
Query Neighborhood Hits	376	Target Neighborhood Hits	165	Shared Neighborhood Hits	50
SwissProt Accessions	P02810, Q4VBP2, Q53XA2, Q6P2F6	Gene names	PRH1
Domain Architecture	No domain graphic available
Description	Salivary acidic proline-rich phosphoprotein 1/2 precursor (PRP-1/PRP- 2) (Parotid proline-rich protein 1/2) (Pr1/Pr2) (Protein C) (Parotid acidic protein) (Pa) (Parotid isoelectric focusing variant protein) (PIF-S) (Parotid double-band protein) (Db-s) [Contains: Salivary acidic proline-rich phosphoprotein 1/2; Salivary acidic proline-rich phosphoprotein 3/4 (PRP-3/PRP-4) (Protein A) (PIF-F) (Db-F); Peptide P-C].

PRR12_HUMAN
θ value	θ > 10 (rank : 575)	NC score	0.172673 (rank : 66)
Query Neighborhood Hits	376	Target Neighborhood Hits	460	Shared Neighborhood Hits	156
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

PRR13_HUMAN
θ value	θ > 10 (rank : 576)	NC score	0.114893 (rank : 121)
Query Neighborhood Hits	376	Target Neighborhood Hits	105	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

PRR13_MOUSE
θ value	θ > 10 (rank : 577)	NC score	0.088056 (rank : 196)
Query Neighborhood Hits	376	Target Neighborhood Hits	54	Shared Neighborhood Hits	24
SwissProt Accessions	Q9CQJ5, Q3U3U4	Gene names	Prr13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

PRRT1_HUMAN
θ value	θ > 10 (rank : 578)	NC score	0.059788 (rank : 382)
Query Neighborhood Hits	376	Target Neighborhood Hits	94	Shared Neighborhood Hits	37
SwissProt Accessions	Q99946, Q96DW3, Q96NQ8	Gene names	PRRT1, C6orf31, NG5
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 1.

PRRT1_MOUSE
θ value	θ > 10 (rank : 579)	NC score	0.064991 (rank : 322)
Query Neighborhood Hits	376	Target Neighborhood Hits	102	Shared Neighborhood Hits	43
SwissProt Accessions	O35449	Gene names	Prrt1, Ng5
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 1.

PS1C2_HUMAN
θ value	θ > 10 (rank : 580)	NC score	0.068464 (rank : 296)
Query Neighborhood Hits	376	Target Neighborhood Hits	66	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UIG4	Gene names	PSORS1C2, C6orf17, SPR1
Domain Architecture	No domain graphic available
Description	Psoriasis susceptibility 1 candidate gene 2 protein precursor (SPR1 protein).

PS1C2_MOUSE
θ value	θ > 10 (rank : 581)	NC score	0.059047 (rank : 393)
Query Neighborhood Hits	376	Target Neighborhood Hits	59	Shared Neighborhood Hits	22
SwissProt Accessions	Q80ZC9	Gene names	Psors1c2, Spr1
Domain Architecture	No domain graphic available
Description	Psoriasis susceptibility 1 candidate gene 2 protein homolog precursor (SPR1 protein).

PTN23_HUMAN
θ value	θ > 10 (rank : 582)	NC score	0.055789 (rank : 431)
Query Neighborhood Hits	376	Target Neighborhood Hits	646	Shared Neighborhood Hits	136
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

PTN23_MOUSE
θ value	θ > 10 (rank : 583)	NC score	0.053368 (rank : 461)
Query Neighborhood Hits	376	Target Neighborhood Hits	726	Shared Neighborhood Hits	151
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

PYGO2_HUMAN
θ value	θ > 10 (rank : 584)	NC score	0.054952 (rank : 444)
Query Neighborhood Hits	376	Target Neighborhood Hits	189	Shared Neighborhood Hits	58
SwissProt Accessions	Q9BRQ0, Q8WYZ4, Q96CY2	Gene names	PYGO2
Domain Architecture
Description	Pygopus homolog 2.

RBM12_MOUSE
θ value	θ > 10 (rank : 585)	NC score	0.062482 (rank : 351)
Query Neighborhood Hits	376	Target Neighborhood Hits	313	Shared Neighborhood Hits	75
SwissProt Accessions	Q8R4X3, Q8K373, Q8R302, Q9CS80	Gene names	Rbm12
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

RD23B_MOUSE
θ value	θ > 10 (rank : 586)	NC score	0.054771 (rank : 448)
Query Neighborhood Hits	376	Target Neighborhood Hits	189	Shared Neighborhood Hits	61
SwissProt Accessions	P54728	Gene names	Rad23b, Mhr23b
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (mHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

RERE_HUMAN
θ value	θ > 10 (rank : 587)	NC score	0.117315 (rank : 117)
Query Neighborhood Hits	376	Target Neighborhood Hits	779	Shared Neighborhood Hits	165
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

RERE_MOUSE
θ value	θ > 10 (rank : 588)	NC score	0.113979 (rank : 124)
Query Neighborhood Hits	376	Target Neighborhood Hits	785	Shared Neighborhood Hits	172
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

RIN3_HUMAN
θ value	θ > 10 (rank : 589)	NC score	0.063092 (rank : 343)
Query Neighborhood Hits	376	Target Neighborhood Hits	227	Shared Neighborhood Hits	79
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

RIN3_MOUSE
θ value	θ > 10 (rank : 590)	NC score	0.064372 (rank : 329)
Query Neighborhood Hits	376	Target Neighborhood Hits	239	Shared Neighborhood Hits	83
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

RPB1_HUMAN
θ value	θ > 10 (rank : 591)	NC score	0.083441 (rank : 212)
Query Neighborhood Hits	376	Target Neighborhood Hits	362	Shared Neighborhood Hits	100
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_MOUSE
θ value	θ > 10 (rank : 592)	NC score	0.084693 (rank : 206)
Query Neighborhood Hits	376	Target Neighborhood Hits	363	Shared Neighborhood Hits	101
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RTN4_HUMAN
θ value	θ > 10 (rank : 593)	NC score	0.056195 (rank : 428)
Query Neighborhood Hits	376	Target Neighborhood Hits	357	Shared Neighborhood Hits	91
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

RTN4_MOUSE
θ value	θ > 10 (rank : 594)	NC score	0.050863 (rank : 504)
Query Neighborhood Hits	376	Target Neighborhood Hits	341	Shared Neighborhood Hits	86
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

RU1C_HUMAN
θ value	θ > 10 (rank : 595)	NC score	0.051491 (rank : 496)
Query Neighborhood Hits	376	Target Neighborhood Hits	81	Shared Neighborhood Hits	29
SwissProt Accessions	P09234	Gene names	SNRPC
Domain Architecture
Description	U1 small nuclear ribonucleoprotein C (U1 snRNP protein C) (U1C protein) (U1-C).

RU1C_MOUSE
θ value	θ > 10 (rank : 596)	NC score	0.053164 (rank : 465)
Query Neighborhood Hits	376	Target Neighborhood Hits	83	Shared Neighborhood Hits	30
SwissProt Accessions	Q62241	Gene names	Snrp1c, Snrpc
Domain Architecture
Description	U1 small nuclear ribonucleoprotein C (U1 snRNP protein C) (U1C protein) (U1-C).

RUSC1_HUMAN
θ value	θ > 10 (rank : 597)	NC score	0.053043 (rank : 469)
Query Neighborhood Hits	376	Target Neighborhood Hits	226	Shared Neighborhood Hits	43
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

RUSC2_HUMAN
θ value	θ > 10 (rank : 598)	NC score	0.051545 (rank : 495)
Query Neighborhood Hits	376	Target Neighborhood Hits	205	Shared Neighborhood Hits	50
SwissProt Accessions	Q8N2Y8, O15080, Q6P1W7	Gene names	RUSC2, KIAA0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

SC24A_MOUSE
θ value	θ > 10 (rank : 599)	NC score	0.055111 (rank : 440)
Query Neighborhood Hits	376	Target Neighborhood Hits	394	Shared Neighborhood Hits	71
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

SC24D_HUMAN
θ value	θ > 10 (rank : 600)	NC score	0.060706 (rank : 363)
Query Neighborhood Hits	376	Target Neighborhood Hits	173	Shared Neighborhood Hits	61
SwissProt Accessions	O94855	Gene names	SEC24D, KIAA0755
Domain Architecture
Description	Protein transport protein Sec24D (SEC24-related protein D).

SDC3_HUMAN
θ value	θ > 10 (rank : 601)	NC score	0.053879 (rank : 458)
Query Neighborhood Hits	376	Target Neighborhood Hits	103	Shared Neighborhood Hits	40
SwissProt Accessions	O75056, Q5T1Z6, Q5T1Z7, Q96CT3, Q96PR8	Gene names	SDC3, KIAA0468
Domain Architecture
Description	Syndecan-3 (SYND3).

SDC3_MOUSE
θ value	θ > 10 (rank : 602)	NC score	0.060528 (rank : 366)
Query Neighborhood Hits	376	Target Neighborhood Hits	107	Shared Neighborhood Hits	41
SwissProt Accessions	Q64519, Q3UDD9, Q6ZQA4, Q7TQD4	Gene names	Sdc3, Kiaa0468
Domain Architecture
Description	Syndecan-3 precursor (SYND3).

SELPL_HUMAN
θ value	θ > 10 (rank : 603)	NC score	0.070634 (rank : 284)
Query Neighborhood Hits	376	Target Neighborhood Hits	68	Shared Neighborhood Hits	24
SwissProt Accessions	Q14242, Q12775	Gene names	SELPLG
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand) (CD162 antigen).

SELV_HUMAN
θ value	θ > 10 (rank : 604)	NC score	0.099152 (rank : 158)
Query Neighborhood Hits	376	Target Neighborhood Hits	118	Shared Neighborhood Hits	55
SwissProt Accessions	P59797	Gene names	SELV
Domain Architecture	No domain graphic available
Description	Selenoprotein V.

SET1A_HUMAN
θ value	θ > 10 (rank : 605)	NC score	0.106556 (rank : 138)
Query Neighborhood Hits	376	Target Neighborhood Hits	690	Shared Neighborhood Hits	143
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SF01_HUMAN
θ value	θ > 10 (rank : 606)	NC score	0.084497 (rank : 207)
Query Neighborhood Hits	376	Target Neighborhood Hits	287	Shared Neighborhood Hits	92
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

SF01_MOUSE
θ value	θ > 10 (rank : 607)	NC score	0.070153 (rank : 289)
Query Neighborhood Hits	376	Target Neighborhood Hits	240	Shared Neighborhood Hits	70
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

SF3A2_HUMAN
θ value	θ > 10 (rank : 608)	NC score	0.126925 (rank : 103)
Query Neighborhood Hits	376	Target Neighborhood Hits	263	Shared Neighborhood Hits	93
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SF3A2_MOUSE
θ value	θ > 10 (rank : 609)	NC score	0.132133 (rank : 92)
Query Neighborhood Hits	376	Target Neighborhood Hits	247	Shared Neighborhood Hits	97
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SFPQ_HUMAN
θ value	θ > 10 (rank : 610)	NC score	0.093871 (rank : 171)
Query Neighborhood Hits	376	Target Neighborhood Hits	986	Shared Neighborhood Hits	165
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

SFPQ_MOUSE
θ value	θ > 10 (rank : 611)	NC score	0.102636 (rank : 148)
Query Neighborhood Hits	376	Target Neighborhood Hits	958	Shared Neighborhood Hits	167
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

SFR15_HUMAN
θ value	θ > 10 (rank : 612)	NC score	0.090436 (rank : 187)
Query Neighborhood Hits	376	Target Neighborhood Hits	368	Shared Neighborhood Hits	86
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

SGIP1_HUMAN
θ value	θ > 10 (rank : 613)	NC score	0.078726 (rank : 230)
Query Neighborhood Hits	376	Target Neighborhood Hits	198	Shared Neighborhood Hits	72
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SGIP1_MOUSE
θ value	θ > 10 (rank : 614)	NC score	0.072791 (rank : 271)
Query Neighborhood Hits	376	Target Neighborhood Hits	180	Shared Neighborhood Hits	66
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SH3G3_MOUSE
θ value	θ > 10 (rank : 615)	NC score	0.090826 (rank : 184)
Query Neighborhood Hits	376	Target Neighborhood Hits	236	Shared Neighborhood Hits	27
SwissProt Accessions	Q62421	Gene names	Sh3gl3, Sh3d2c, Sh3d2c2
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (SH3p13).

SH3K1_HUMAN
θ value	θ > 10 (rank : 616)	NC score	0.075068 (rank : 250)
Query Neighborhood Hits	376	Target Neighborhood Hits	341	Shared Neighborhood Hits	46
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

SH3K1_MOUSE
θ value	θ > 10 (rank : 617)	NC score	0.078420 (rank : 233)
Query Neighborhood Hits	376	Target Neighborhood Hits	332	Shared Neighborhood Hits	50
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

SHAN1_HUMAN
θ value	θ > 10 (rank : 618)	NC score	0.062989 (rank : 345)
Query Neighborhood Hits	376	Target Neighborhood Hits	1041	Shared Neighborhood Hits	150
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SHLB1_HUMAN
θ value	θ > 10 (rank : 619)	NC score	0.073415 (rank : 265)
Query Neighborhood Hits	376	Target Neighborhood Hits	96	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y371, Q9H3Z0, Q9NR47, Q9NYA9	Gene names	SH3GLB1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1) (Bax- interacting factor 1) (Bif-1).

SHLB1_MOUSE
θ value	θ > 10 (rank : 620)	NC score	0.072945 (rank : 269)
Query Neighborhood Hits	376	Target Neighborhood Hits	101	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JK48, Q8CDS9, Q8VI52, Q9CT31	Gene names	Sh3glb1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1).

SMOO_HUMAN
θ value	θ > 10 (rank : 621)	NC score	0.070468 (rank : 288)
Query Neighborhood Hits	376	Target Neighborhood Hits	391	Shared Neighborhood Hits	97
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

SMR1_MOUSE
θ value	θ > 10 (rank : 622)	NC score	0.096890 (rank : 161)
Query Neighborhood Hits	376	Target Neighborhood Hits	103	Shared Neighborhood Hits	54
SwissProt Accessions	Q61900	Gene names	Smr1, Msg1
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 1 precursor (Salivary protein MSG1).

SMR3A_HUMAN
θ value	θ > 10 (rank : 623)	NC score	0.114516 (rank : 122)
Query Neighborhood Hits	376	Target Neighborhood Hits	93	Shared Neighborhood Hits	46
SwissProt Accessions	Q99954	Gene names	SMR3A, PBI, PROL5
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog A precursor (Proline-rich protein 5) (Proline-rich protein PBI).

SMR3B_HUMAN
θ value	θ > 10 (rank : 624)	NC score	0.054405 (rank : 451)
Query Neighborhood Hits	376	Target Neighborhood Hits	46	Shared Neighborhood Hits	21
SwissProt Accessions	P02814, Q9UBN0, Q9UCT0	Gene names	SMR3B, PBII, PROL3
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog B precursor (Proline-rich protein 3) (Proline-rich peptide P-B) [Contains: Peptide P-A; Peptide D1A].

SMRC2_HUMAN
θ value	θ > 10 (rank : 625)	NC score	0.054158 (rank : 453)
Query Neighborhood Hits	376	Target Neighborhood Hits	499	Shared Neighborhood Hits	87
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

SMRC2_MOUSE
θ value	θ > 10 (rank : 626)	NC score	0.055078 (rank : 441)
Query Neighborhood Hits	376	Target Neighborhood Hits	487	Shared Neighborhood Hits	84
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

SON_MOUSE
θ value	θ > 10 (rank : 627)	NC score	0.082449 (rank : 217)
Query Neighborhood Hits	376	Target Neighborhood Hits	957	Shared Neighborhood Hits	127
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

SPR2H_MOUSE
θ value	θ > 10 (rank : 628)	NC score	0.055052 (rank : 442)
Query Neighborhood Hits	376	Target Neighborhood Hits	82	Shared Neighborhood Hits	27
SwissProt Accessions	O70559	Gene names	Sprr2h
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2H.

SPRR3_MOUSE
θ value	θ > 10 (rank : 629)	NC score	0.052984 (rank : 471)
Query Neighborhood Hits	376	Target Neighborhood Hits	106	Shared Neighborhood Hits	31
SwissProt Accessions	O09116	Gene names	Sprr3
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta).

SRBS1_HUMAN
θ value	θ > 10 (rank : 630)	NC score	0.091711 (rank : 179)
Query Neighborhood Hits	376	Target Neighborhood Hits	396	Shared Neighborhood Hits	67
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SRC8_HUMAN
θ value	θ > 10 (rank : 631)	NC score	0.052868 (rank : 472)
Query Neighborhood Hits	376	Target Neighborhood Hits	269	Shared Neighborhood Hits	32
SwissProt Accessions	Q14247	Gene names	CTTN, EMS1
Domain Architecture
Description	Src substrate cortactin (Amplaxin) (Oncogene EMS1).

SRC8_MOUSE
θ value	θ > 10 (rank : 632)	NC score	0.057366 (rank : 413)
Query Neighborhood Hits	376	Target Neighborhood Hits	292	Shared Neighborhood Hits	37
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

SRRM1_HUMAN
θ value	θ > 10 (rank : 633)	NC score	0.151825 (rank : 75)
Query Neighborhood Hits	376	Target Neighborhood Hits	690	Shared Neighborhood Hits	149
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SRRM1_MOUSE
θ value	θ > 10 (rank : 634)	NC score	0.160142 (rank : 72)
Query Neighborhood Hits	376	Target Neighborhood Hits	966	Shared Neighborhood Hits	173
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

STAC3_HUMAN
θ value	θ > 10 (rank : 635)	NC score	0.061953 (rank : 354)
Query Neighborhood Hits	376	Target Neighborhood Hits	228	Shared Neighborhood Hits	28
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC3_MOUSE
θ value	θ > 10 (rank : 636)	NC score	0.063829 (rank : 335)
Query Neighborhood Hits	376	Target Neighborhood Hits	232	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC_HUMAN
θ value	θ > 10 (rank : 637)	NC score	0.064013 (rank : 333)
Query Neighborhood Hits	376	Target Neighborhood Hits	276	Shared Neighborhood Hits	32
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

STAC_MOUSE
θ value	θ > 10 (rank : 638)	NC score	0.066033 (rank : 317)
Query Neighborhood Hits	376	Target Neighborhood Hits	268	Shared Neighborhood Hits	31
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

SYN1_HUMAN
θ value	θ > 10 (rank : 639)	NC score	0.106603 (rank : 137)
Query Neighborhood Hits	376	Target Neighborhood Hits	419	Shared Neighborhood Hits	140
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

SYN1_MOUSE
θ value	θ > 10 (rank : 640)	NC score	0.096889 (rank : 162)
Query Neighborhood Hits	376	Target Neighborhood Hits	363	Shared Neighborhood Hits	128
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

SYNJ2_HUMAN
θ value	θ > 10 (rank : 641)	NC score	0.064172 (rank : 331)
Query Neighborhood Hits	376	Target Neighborhood Hits	136	Shared Neighborhood Hits	51
SwissProt Accessions	O15056, Q5TA13, Q5TA16, Q5TA19, Q86XK0, Q8IZA8, Q9H226	Gene names	SYNJ2, KIAA0348
Domain Architecture	No domain graphic available
Description	Synaptojanin-2 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 2).

SYNJ2_MOUSE
θ value	θ > 10 (rank : 642)	NC score	0.052680 (rank : 478)
Query Neighborhood Hits	376	Target Neighborhood Hits	87	Shared Neighborhood Hits	28
SwissProt Accessions	Q9D2G5, O35404, O88399, O88400, O88401, O88402, O88403, O88404	Gene names	Synj2, Kiaa0348
Domain Architecture
Description	Synaptojanin-2 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 2).

SYP2L_HUMAN
θ value	θ > 10 (rank : 643)	NC score	0.075314 (rank : 247)
Query Neighborhood Hits	376	Target Neighborhood Hits	400	Shared Neighborhood Hits	102
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

SYP2L_MOUSE
θ value	θ > 10 (rank : 644)	NC score	0.060338 (rank : 373)
Query Neighborhood Hits	376	Target Neighborhood Hits	289	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

T22D2_HUMAN
θ value	θ > 10 (rank : 645)	NC score	0.104446 (rank : 144)
Query Neighborhood Hits	376	Target Neighborhood Hits	250	Shared Neighborhood Hits	87
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

TACC2_MOUSE
θ value	θ > 10 (rank : 646)	NC score	0.055600 (rank : 434)
Query Neighborhood Hits	376	Target Neighborhood Hits	774	Shared Neighborhood Hits	90
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

TAF4_HUMAN
θ value	θ > 10 (rank : 647)	NC score	0.163077 (rank : 70)
Query Neighborhood Hits	376	Target Neighborhood Hits	687	Shared Neighborhood Hits	162
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

TARA_HUMAN
θ value	θ > 10 (rank : 648)	NC score	0.066255 (rank : 315)
Query Neighborhood Hits	376	Target Neighborhood Hits	1626	Shared Neighborhood Hits	157
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TARA_MOUSE
θ value	θ > 10 (rank : 649)	NC score	0.058776 (rank : 398)
Query Neighborhood Hits	376	Target Neighborhood Hits	1133	Shared Neighborhood Hits	117
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TAU_HUMAN
θ value	θ > 10 (rank : 650)	NC score	0.074462 (rank : 255)
Query Neighborhood Hits	376	Target Neighborhood Hits	448	Shared Neighborhood Hits	87
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TB182_HUMAN
θ value	θ > 10 (rank : 651)	NC score	0.063481 (rank : 340)
Query Neighborhood Hits	376	Target Neighborhood Hits	414	Shared Neighborhood Hits	80
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

TCOF_HUMAN
θ value	θ > 10 (rank : 652)	NC score	0.090343 (rank : 188)
Query Neighborhood Hits	376	Target Neighborhood Hits	543	Shared Neighborhood Hits	91
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

TCOF_MOUSE
θ value	θ > 10 (rank : 653)	NC score	0.104190 (rank : 145)
Query Neighborhood Hits	376	Target Neighborhood Hits	471	Shared Neighborhood Hits	86
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

TCRG1_HUMAN
θ value	θ > 10 (rank : 654)	NC score	0.085884 (rank : 203)
Query Neighborhood Hits	376	Target Neighborhood Hits	929	Shared Neighborhood Hits	113
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TCRG1_MOUSE
θ value	θ > 10 (rank : 655)	NC score	0.089521 (rank : 192)
Query Neighborhood Hits	376	Target Neighborhood Hits	947	Shared Neighborhood Hits	122
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

TENS1_HUMAN
θ value	θ > 10 (rank : 656)	NC score	0.051970 (rank : 486)
Query Neighborhood Hits	376	Target Neighborhood Hits	400	Shared Neighborhood Hits	70
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

TGON2_HUMAN
θ value	θ > 10 (rank : 657)	NC score	0.061173 (rank : 358)
Query Neighborhood Hits	376	Target Neighborhood Hits	1037	Shared Neighborhood Hits	102
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TM108_HUMAN
θ value	θ > 10 (rank : 658)	NC score	0.060109 (rank : 377)
Query Neighborhood Hits	376	Target Neighborhood Hits	166	Shared Neighborhood Hits	52
SwissProt Accessions	Q6UXF1, Q9BQH1, Q9BW81, Q9C0H3	Gene names	TMEM108, KIAA1690
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

TM108_MOUSE
θ value	θ > 10 (rank : 659)	NC score	0.071342 (rank : 282)
Query Neighborhood Hits	376	Target Neighborhood Hits	336	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

TMAP1_HUMAN
θ value	θ > 10 (rank : 660)	NC score	0.074620 (rank : 253)
Query Neighborhood Hits	376	Target Neighborhood Hits	140	Shared Neighborhood Hits	44
SwissProt Accessions	P84157	Gene names	TMAP1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

TP53B_MOUSE
θ value	θ > 10 (rank : 661)	NC score	0.057696 (rank : 410)
Query Neighborhood Hits	376	Target Neighborhood Hits	644	Shared Neighborhood Hits	87
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TROAP_HUMAN
θ value	θ > 10 (rank : 662)	NC score	0.053915 (rank : 457)
Query Neighborhood Hits	376	Target Neighborhood Hits	258	Shared Neighborhood Hits	60
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

UN13A_HUMAN
θ value	θ > 10 (rank : 663)	NC score	0.055488 (rank : 435)
Query Neighborhood Hits	376	Target Neighborhood Hits	285	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

UN13B_HUMAN
θ value	θ > 10 (rank : 664)	NC score	0.050942 (rank : 502)
Query Neighborhood Hits	376	Target Neighborhood Hits	217	Shared Neighborhood Hits	21
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

VASP_HUMAN
θ value	θ > 10 (rank : 665)	NC score	0.060487 (rank : 367)
Query Neighborhood Hits	376	Target Neighborhood Hits	201	Shared Neighborhood Hits	69
SwissProt Accessions	P50552, Q6PIZ1, Q93035	Gene names	VASP
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

VASP_MOUSE
θ value	θ > 10 (rank : 666)	NC score	0.057317 (rank : 414)
Query Neighborhood Hits	376	Target Neighborhood Hits	195	Shared Neighborhood Hits	63
SwissProt Accessions	P70460, Q3TAP0, Q3TCD2, Q3U0C2, Q3UDF1, Q91VD2, Q9R214	Gene names	Vasp
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

VAV2_HUMAN
θ value	θ > 10 (rank : 667)	NC score	0.057389 (rank : 412)
Query Neighborhood Hits	376	Target Neighborhood Hits	453	Shared Neighborhood Hits	40
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

VAV2_MOUSE
θ value	θ > 10 (rank : 668)	NC score	0.058095 (rank : 405)
Query Neighborhood Hits	376	Target Neighborhood Hits	456	Shared Neighborhood Hits	40
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

VAV3_HUMAN
θ value	θ > 10 (rank : 669)	NC score	0.062579 (rank : 348)
Query Neighborhood Hits	376	Target Neighborhood Hits	398	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

VAV3_MOUSE
θ value	θ > 10 (rank : 670)	NC score	0.062604 (rank : 347)
Query Neighborhood Hits	376	Target Neighborhood Hits	404	Shared Neighborhood Hits	39
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

VAV_MOUSE
θ value	θ > 10 (rank : 671)	NC score	0.050894 (rank : 503)
Query Neighborhood Hits	376	Target Neighborhood Hits	430	Shared Neighborhood Hits	36
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

VCX1_HUMAN
θ value	θ > 10 (rank : 672)	NC score	0.058739 (rank : 399)
Query Neighborhood Hits	376	Target Neighborhood Hits	129	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H320, Q9P0H3	Gene names	VCX, VCX1, VCX10R, VCXB1
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 1 (VCX-B1 protein) (Variably charged protein X-B1) (Variable charge protein on X with ten repeats) (VCX- 10r).

VCX3_HUMAN
θ value	θ > 10 (rank : 673)	NC score	0.065038 (rank : 321)
Query Neighborhood Hits	376	Target Neighborhood Hits	105	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NNX9, Q9P0H4	Gene names	VCX3A, VCX3, VCX8R, VCXA
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 3 (VCX-A protein) (Variably charged protein X-A) (Variable charge protein on X with eight repeats) (VCX- 8r).

VCXC_HUMAN
θ value	θ > 10 (rank : 674)	NC score	0.059083 (rank : 392)
Query Neighborhood Hits	376	Target Neighborhood Hits	139	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H321	Gene names	VCXC
Domain Architecture	No domain graphic available
Description	VCX-C protein (Variably charged protein X-C).

VINEX_HUMAN
θ value	θ > 10 (rank : 675)	NC score	0.077655 (rank : 237)
Query Neighborhood Hits	376	Target Neighborhood Hits	270	Shared Neighborhood Hits	48
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

VINEX_MOUSE
θ value	θ > 10 (rank : 676)	NC score	0.078119 (rank : 235)
Query Neighborhood Hits	376	Target Neighborhood Hits	286	Shared Neighborhood Hits	45
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

WASF1_HUMAN
θ value	θ > 10 (rank : 677)	NC score	0.082332 (rank : 218)
Query Neighborhood Hits	376	Target Neighborhood Hits	260	Shared Neighborhood Hits	104
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

WASF1_MOUSE
θ value	θ > 10 (rank : 678)	NC score	0.082989 (rank : 215)
Query Neighborhood Hits	376	Target Neighborhood Hits	261	Shared Neighborhood Hits	103
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

WASF2_HUMAN
θ value	θ > 10 (rank : 679)	NC score	0.092200 (rank : 177)
Query Neighborhood Hits	376	Target Neighborhood Hits	280	Shared Neighborhood Hits	107
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

WASF2_MOUSE
θ value	θ > 10 (rank : 680)	NC score	0.103731 (rank : 146)
Query Neighborhood Hits	376	Target Neighborhood Hits	315	Shared Neighborhood Hits	125
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

WASF3_HUMAN
θ value	θ > 10 (rank : 681)	NC score	0.064835 (rank : 325)
Query Neighborhood Hits	376	Target Neighborhood Hits	204	Shared Neighborhood Hits	76
SwissProt Accessions	Q9UPY6, O94974	Gene names	WASF3, KIAA0900, SCAR3, WAVE3
Domain Architecture
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3) (Verprolin homology domain-containing protein 3).

WASF3_MOUSE
θ value	θ > 10 (rank : 682)	NC score	0.060476 (rank : 368)
Query Neighborhood Hits	376	Target Neighborhood Hits	188	Shared Neighborhood Hits	77
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

WASF4_HUMAN
θ value	θ > 10 (rank : 683)	NC score	0.095411 (rank : 167)
Query Neighborhood Hits	376	Target Neighborhood Hits	282	Shared Neighborhood Hits	117
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

WASIP_HUMAN
θ value	θ > 10 (rank : 684)	NC score	0.171213 (rank : 67)
Query Neighborhood Hits	376	Target Neighborhood Hits	458	Shared Neighborhood Hits	156
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

WASIP_MOUSE
θ value	θ > 10 (rank : 685)	NC score	0.164645 (rank : 69)
Query Neighborhood Hits	376	Target Neighborhood Hits	392	Shared Neighborhood Hits	143
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

WASL_HUMAN
θ value	θ > 10 (rank : 686)	NC score	0.102410 (rank : 149)
Query Neighborhood Hits	376	Target Neighborhood Hits	312	Shared Neighborhood Hits	114
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WASL_MOUSE
θ value	θ > 10 (rank : 687)	NC score	0.110016 (rank : 132)
Query Neighborhood Hits	376	Target Neighborhood Hits	339	Shared Neighborhood Hits	125
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WASP_HUMAN
θ value	θ > 10 (rank : 688)	NC score	0.074621 (rank : 252)
Query Neighborhood Hits	376	Target Neighborhood Hits	195	Shared Neighborhood Hits	88
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

WASP_MOUSE
θ value	θ > 10 (rank : 689)	NC score	0.073127 (rank : 267)
Query Neighborhood Hits	376	Target Neighborhood Hits	223	Shared Neighborhood Hits	86
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

WBP11_HUMAN
θ value	θ > 10 (rank : 690)	NC score	0.127687 (rank : 101)
Query Neighborhood Hits	376	Target Neighborhood Hits	354	Shared Neighborhood Hits	106
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

WBP11_MOUSE
θ value	θ > 10 (rank : 691)	NC score	0.121038 (rank : 114)
Query Neighborhood Hits	376	Target Neighborhood Hits	362	Shared Neighborhood Hits	112
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

WBS14_HUMAN
θ value	θ > 10 (rank : 692)	NC score	0.083954 (rank : 209)
Query Neighborhood Hits	376	Target Neighborhood Hits	273	Shared Neighborhood Hits	91
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

WIRE_HUMAN
θ value	θ > 10 (rank : 693)	NC score	0.139268 (rank : 82)
Query Neighborhood Hits	376	Target Neighborhood Hits	329	Shared Neighborhood Hits	124
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

WIRE_MOUSE
θ value	θ > 10 (rank : 694)	NC score	0.132336 (rank : 91)
Query Neighborhood Hits	376	Target Neighborhood Hits	310	Shared Neighborhood Hits	124
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

YLPM1_HUMAN
θ value	θ > 10 (rank : 695)	NC score	0.096461 (rank : 163)
Query Neighborhood Hits	376	Target Neighborhood Hits	670	Shared Neighborhood Hits	126
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

YLPM1_MOUSE
θ value	θ > 10 (rank : 696)	NC score	0.124747 (rank : 106)
Query Neighborhood Hits	376	Target Neighborhood Hits	505	Shared Neighborhood Hits	150
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

ZN207_HUMAN
θ value	θ > 10 (rank : 697)	NC score	0.114063 (rank : 123)
Query Neighborhood Hits	376	Target Neighborhood Hits	326	Shared Neighborhood Hits	79
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

ZN598_HUMAN
θ value	θ > 10 (rank : 698)	NC score	0.059486 (rank : 386)
Query Neighborhood Hits	376	Target Neighborhood Hits	339	Shared Neighborhood Hits	66
SwissProt Accessions	Q86UK7, Q8IW49, Q8N3D9, Q96FG3, Q9H7J3	Gene names	ZNF598
Domain Architecture	No domain graphic available
Description	Zinc finger protein 598.

ZYX_HUMAN
θ value	θ > 10 (rank : 699)	NC score	0.051580 (rank : 493)
Query Neighborhood Hits	376	Target Neighborhood Hits	387	Shared Neighborhood Hits	91
SwissProt Accessions	Q15942	Gene names	ZYX
Domain Architecture
Description	Zyxin (Zyxin-2).

ZYX_MOUSE
θ value	θ > 10 (rank : 700)	NC score	0.051797 (rank : 489)
Query Neighborhood Hits	376	Target Neighborhood Hits	347	Shared Neighborhood Hits	81
SwissProt Accessions	Q62523, P70461	Gene names	Zyx
Domain Architecture
Description	Zyxin.

Hits sorted by NC score

3BP1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	376	Target Neighborhood Hits	376	Shared Neighborhood Hits	376
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

3BP1_MOUSE
NC score	0.951607 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	376	Target Neighborhood Hits	238	Shared Neighborhood Hits	158
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

RHG09_HUMAN
NC score	0.802626 (rank : 3)	θ value	9.56915e-18 (rank : 23)
Query Neighborhood Hits	376	Target Neighborhood Hits	186	Shared Neighborhood Hits	77
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

RHG06_HUMAN
NC score	0.789867 (rank : 4)	θ value	7.32683e-18 (rank : 22)
Query Neighborhood Hits	376	Target Neighborhood Hits	114	Shared Neighborhood Hits	69
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RHG06_MOUSE
NC score	0.789350 (rank : 5)	θ value	1.92812e-18 (rank : 20)
Query Neighborhood Hits	376	Target Neighborhood Hits	105	Shared Neighborhood Hits	66
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

TCGAP_MOUSE
NC score	0.781580 (rank : 6)	θ value	1.42661e-21 (rank : 11)
Query Neighborhood Hits	376	Target Neighborhood Hits	409	Shared Neighborhood Hits	140
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

RHG12_HUMAN
NC score	0.781147 (rank : 7)	θ value	7.0802e-21 (rank : 15)
Query Neighborhood Hits	376	Target Neighborhood Hits	190	Shared Neighborhood Hits	66
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RHG12_MOUSE
NC score	0.781075 (rank : 8)	θ value	3.17815e-21 (rank : 13)
Query Neighborhood Hits	376	Target Neighborhood Hits	204	Shared Neighborhood Hits	68
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RHG01_HUMAN
NC score	0.779564 (rank : 9)	θ value	1.86321e-21 (rank : 12)
Query Neighborhood Hits	376	Target Neighborhood Hits	75	Shared Neighborhood Hits	62
SwissProt Accessions	Q07960	Gene names	ARHGAP1, CDC42GAP, RHOGAP1
Domain Architecture
Description	Rho-GTPase-activating protein 1 (GTPase-activating protein rhoOGAP) (Rho-related small GTPase protein activator) (CDC42 GTPase-activating protein) (p50-RhoGAP).

GMIP_MOUSE
NC score	0.775944 (rank : 10)	θ value	1.058e-16 (rank : 32)
Query Neighborhood Hits	376	Target Neighborhood Hits	202	Shared Neighborhood Hits	74
SwissProt Accessions	Q6PGG2, Q6P9S3	Gene names	Gmip
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

GMIP_HUMAN
NC score	0.773710 (rank : 11)	θ value	2.60593e-15 (rank : 38)
Query Neighborhood Hits	376	Target Neighborhood Hits	225	Shared Neighborhood Hits	80
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

GRLF1_HUMAN
NC score	0.768116 (rank : 12)	θ value	1.92812e-18 (rank : 19)
Query Neighborhood Hits	376	Target Neighborhood Hits	167	Shared Neighborhood Hits	77
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

RHG08_MOUSE
NC score	0.764716 (rank : 13)	θ value	6.62687e-19 (rank : 18)
Query Neighborhood Hits	376	Target Neighborhood Hits	73	Shared Neighborhood Hits	62
SwissProt Accessions	Q9CXP4, Q99JY7	Gene names	Arhgap8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RHG08_HUMAN
NC score	0.763373 (rank : 14)	θ value	2.5182e-18 (rank : 21)
Query Neighborhood Hits	376	Target Neighborhood Hits	88	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NSG0, O75983, O95695, Q96RW1, Q96RW2, Q9HA49, Q9HC46, Q9NVX8, Q9NXL1, Q9UH20	Gene names	ARHGAP8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RGAP1_HUMAN
NC score	0.756206 (rank : 15)	θ value	9.26847e-13 (rank : 47)
Query Neighborhood Hits	376	Target Neighborhood Hits	189	Shared Neighborhood Hits	70
SwissProt Accessions	Q9H0H5, Q6PJ26, Q9NWN2, Q9P250, Q9P2W2	Gene names	RACGAP1, KIAA1478, MGCRACGAP
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RHG18_MOUSE
NC score	0.754501 (rank : 16)	θ value	1.09485e-13 (rank : 45)
Query Neighborhood Hits	376	Target Neighborhood Hits	110	Shared Neighborhood Hits	63
SwissProt Accessions	Q8K0Q5, Q8BP03, Q8R196	Gene names	Arhgap18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18.

RHG18_HUMAN
NC score	0.753504 (rank : 17)	θ value	6.41864e-14 (rank : 44)
Query Neighborhood Hits	376	Target Neighborhood Hits	90	Shared Neighborhood Hits	62
SwissProt Accessions	Q8N392, Q58EZ3, Q6P679, Q6PJD7, Q96S64	Gene names	ARHGAP18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18 (MacGAP).

RGAP1_MOUSE
NC score	0.751045 (rank : 18)	θ value	1.58096e-12 (rank : 48)
Query Neighborhood Hits	376	Target Neighborhood Hits	185	Shared Neighborhood Hits	69
SwissProt Accessions	Q9WVM1, Q3THR5, Q3TI41, Q3TM81	Gene names	Racgap1, Mgcracgap
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

CHIO_MOUSE
NC score	0.749590 (rank : 19)	θ value	3.75424e-22 (rank : 7)
Query Neighborhood Hits	376	Target Neighborhood Hits	130	Shared Neighborhood Hits	64
SwissProt Accessions	Q80XD1, Q9D9W2, Q9ER57	Gene names	Chn2, Arhgap3, Bch
Domain Architecture	No domain graphic available
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

TAGAP_HUMAN
NC score	0.745326 (rank : 20)	θ value	5.42112e-21 (rank : 14)
Query Neighborhood Hits	376	Target Neighborhood Hits	82	Shared Neighborhood Hits	61
SwissProt Accessions	Q8N103, Q2NKM8, Q8NI40, Q96KZ2, Q96QA2	Gene names	TAGAP, TAGAP1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

TAGAP_MOUSE
NC score	0.743410 (rank : 21)	θ value	1.24977e-17 (rank : 25)
Query Neighborhood Hits	376	Target Neighborhood Hits	83	Shared Neighborhood Hits	62
SwissProt Accessions	Q8K2L9, Q920D6	Gene names	Tagap, Tagap1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

RHG05_MOUSE
NC score	0.728366 (rank : 22)	θ value	1.80466e-16 (rank : 34)
Query Neighborhood Hits	376	Target Neighborhood Hits	165	Shared Neighborhood Hits	67
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

OPHN1_HUMAN
NC score	0.726629 (rank : 23)	θ value	6.41864e-14 (rank : 43)
Query Neighborhood Hits	376	Target Neighborhood Hits	161	Shared Neighborhood Hits	72
SwissProt Accessions	O60890, Q5JQ81, Q8WX47	Gene names	OPHN1
Domain Architecture
Description	Oligophrenin 1.

OPHN1_MOUSE
NC score	0.724331 (rank : 24)	θ value	3.76295e-14 (rank : 42)
Query Neighborhood Hits	376	Target Neighborhood Hits	174	Shared Neighborhood Hits	70
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

CHIN_MOUSE
NC score	0.722877 (rank : 25)	θ value	1.99067e-23 (rank : 5)
Query Neighborhood Hits	376	Target Neighborhood Hits	229	Shared Neighborhood Hits	66
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

RHG04_HUMAN
NC score	0.722556 (rank : 26)	θ value	7.56453e-23 (rank : 6)
Query Neighborhood Hits	376	Target Neighborhood Hits	307	Shared Neighborhood Hits	81
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

CHIN_HUMAN
NC score	0.719951 (rank : 27)	θ value	6.84181e-24 (rank : 3)
Query Neighborhood Hits	376	Target Neighborhood Hits	227	Shared Neighborhood Hits	65
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

RHG05_HUMAN
NC score	0.719086 (rank : 28)	θ value	6.20254e-17 (rank : 31)
Query Neighborhood Hits	376	Target Neighborhood Hits	158	Shared Neighborhood Hits	66
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

CHIO_HUMAN
NC score	0.717738 (rank : 29)	θ value	1.42661e-21 (rank : 10)
Query Neighborhood Hits	376	Target Neighborhood Hits	220	Shared Neighborhood Hits	66
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

ABR_HUMAN
NC score	0.717347 (rank : 30)	θ value	1.5242e-23 (rank : 4)
Query Neighborhood Hits	376	Target Neighborhood Hits	166	Shared Neighborhood Hits	70
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

RHG25_MOUSE
NC score	0.716733 (rank : 31)	θ value	2.13179e-17 (rank : 29)
Query Neighborhood Hits	376	Target Neighborhood Hits	492	Shared Neighborhood Hits	97
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

SRGP2_HUMAN
NC score	0.707085 (rank : 32)	θ value	9.56915e-18 (rank : 24)
Query Neighborhood Hits	376	Target Neighborhood Hits	331	Shared Neighborhood Hits	88
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

BCR_HUMAN
NC score	0.704113 (rank : 33)	θ value	8.36355e-22 (rank : 9)
Query Neighborhood Hits	376	Target Neighborhood Hits	204	Shared Neighborhood Hits	85
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

RHG26_HUMAN
NC score	0.703791 (rank : 34)	θ value	1.63225e-17 (rank : 27)
Query Neighborhood Hits	376	Target Neighborhood Hits	281	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

RHG07_MOUSE
NC score	0.703525 (rank : 35)	θ value	1.058e-16 (rank : 33)
Query Neighborhood Hits	376	Target Neighborhood Hits	103	Shared Neighborhood Hits	66
SwissProt Accessions	Q9R0Z9, Q8R541	Gene names	Dlc1, Arhgap7, Stard12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein homolog) (Dlc-1) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

TCGAP_HUMAN
NC score	0.703298 (rank : 36)	θ value	4.9032e-22 (rank : 8)
Query Neighborhood Hits	376	Target Neighborhood Hits	872	Shared Neighborhood Hits	179
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

SRGP2_MOUSE
NC score	0.700280 (rank : 37)	θ value	2.13179e-17 (rank : 30)
Query Neighborhood Hits	376	Target Neighborhood Hits	324	Shared Neighborhood Hits	88
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

RHG07_HUMAN
NC score	0.698041 (rank : 38)	θ value	6.85773e-16 (rank : 36)
Query Neighborhood Hits	376	Target Neighborhood Hits	108	Shared Neighborhood Hits	65
SwissProt Accessions	Q96QB1, O14868, O43199, Q9C0E0	Gene names	DLC1, ARHGAP7, KIAA1723, STARD12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein) (Dlc-1) (HP protein) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

RHG25_HUMAN
NC score	0.695378 (rank : 39)	θ value	1.63225e-17 (rank : 26)
Query Neighborhood Hits	376	Target Neighborhood Hits	550	Shared Neighborhood Hits	90
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

FNBP2_HUMAN
NC score	0.691799 (rank : 40)	θ value	2.13179e-17 (rank : 28)
Query Neighborhood Hits	376	Target Neighborhood Hits	432	Shared Neighborhood Hits	97
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

SRGP1_HUMAN
NC score	0.691157 (rank : 41)	θ value	5.25075e-16 (rank : 35)
Query Neighborhood Hits	376	Target Neighborhood Hits	390	Shared Neighborhood Hits	92
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

RBP1_MOUSE
NC score	0.688653 (rank : 42)	θ value	4.59992e-12 (rank : 49)
Query Neighborhood Hits	376	Target Neighborhood Hits	493	Shared Neighborhood Hits	84
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

RBP1_HUMAN
NC score	0.668470 (rank : 43)	θ value	3.89403e-11 (rank : 51)
Query Neighborhood Hits	376	Target Neighborhood Hits	521	Shared Neighborhood Hits	85
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

STAR8_MOUSE
NC score	0.665856 (rank : 44)	θ value	2.88119e-14 (rank : 41)
Query Neighborhood Hits	376	Target Neighborhood Hits	101	Shared Neighborhood Hits	65
SwissProt Accessions	Q8K031, Q3UZC7, Q6A0A8, Q6P5E0, Q8R3X8	Gene names	Stard8, Kiaa0189
Domain Architecture	No domain graphic available
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

STAR8_HUMAN
NC score	0.665215 (rank : 45)	θ value	1.68911e-14 (rank : 40)
Query Neighborhood Hits	376	Target Neighborhood Hits	216	Shared Neighborhood Hits	84
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

STA13_HUMAN
NC score	0.660177 (rank : 46)	θ value	1.16975e-15 (rank : 37)
Query Neighborhood Hits	376	Target Neighborhood Hits	89	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y3M8, Q5HYH1, Q5TAE3, Q6UN61, Q86TP6, Q86WQ3, Q86XT1	Gene names	STARD13, DLC2, GT650
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13) (46H23.2) (Deleted in liver cancer protein 2) (Rho GTPase-activating protein).

STA13_MOUSE
NC score	0.652780 (rank : 47)	θ value	3.40345e-15 (rank : 39)
Query Neighborhood Hits	376	Target Neighborhood Hits	89	Shared Neighborhood Hits	59
SwissProt Accessions	Q923Q2, Q8K369	Gene names	Stard13
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13).

CEND2_HUMAN
NC score	0.593536 (rank : 48)	θ value	7.09661e-13 (rank : 46)
Query Neighborhood Hits	376	Target Neighborhood Hits	166	Shared Neighborhood Hits	66
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

CE005_HUMAN
NC score	0.588653 (rank : 49)	θ value	9.92553e-07 (rank : 57)
Query Neighborhood Hits	376	Target Neighborhood Hits	213	Shared Neighborhood Hits	69
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

CE005_MOUSE
NC score	0.585466 (rank : 50)	θ value	2.21117e-06 (rank : 59)
Query Neighborhood Hits	376	Target Neighborhood Hits	238	Shared Neighborhood Hits	70
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

K1688_MOUSE
NC score	0.569561 (rank : 51)	θ value	4.0297e-08 (rank : 54)
Query Neighborhood Hits	376	Target Neighborhood Hits	188	Shared Neighborhood Hits	77
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

CEND3_MOUSE
NC score	0.567702 (rank : 52)	θ value	1.33837e-11 (rank : 50)
Query Neighborhood Hits	376	Target Neighborhood Hits	228	Shared Neighborhood Hits	92
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

K1688_HUMAN
NC score	0.557693 (rank : 53)	θ value	2.36244e-08 (rank : 53)
Query Neighborhood Hits	376	Target Neighborhood Hits	217	Shared Neighborhood Hits	75
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

CEND3_HUMAN
NC score	0.557397 (rank : 54)	θ value	1.47974e-10 (rank : 52)
Query Neighborhood Hits	376	Target Neighborhood Hits	275	Shared Neighborhood Hits	101
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

CEND1_MOUSE
NC score	0.487107 (rank : 55)	θ value	2.88788e-06 (rank : 60)
Query Neighborhood Hits	376	Target Neighborhood Hits	260	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

CEND1_HUMAN
NC score	0.466239 (rank : 56)	θ value	1.43324e-05 (rank : 64)
Query Neighborhood Hits	376	Target Neighborhood Hits	284	Shared Neighborhood Hits	65
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

MYO9B_HUMAN
NC score	0.426516 (rank : 57)	θ value	1.5773e-20 (rank : 17)
Query Neighborhood Hits	376	Target Neighborhood Hits	641	Shared Neighborhood Hits	136
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

MYO9B_MOUSE
NC score	0.424182 (rank : 58)	θ value	1.2077e-20 (rank : 16)
Query Neighborhood Hits	376	Target Neighborhood Hits	311	Shared Neighborhood Hits	88
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

P85A_HUMAN
NC score	0.373968 (rank : 59)	θ value	3.19293e-05 (rank : 67)
Query Neighborhood Hits	376	Target Neighborhood Hits	479	Shared Neighborhood Hits	82
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

P85A_MOUSE
NC score	0.372535 (rank : 60)	θ value	1.29631e-06 (rank : 58)
Query Neighborhood Hits	376	Target Neighborhood Hits	435	Shared Neighborhood Hits	84
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

I5P2_HUMAN
NC score	0.370565 (rank : 61)	θ value	4.92598e-06 (rank : 63)
Query Neighborhood Hits	376	Target Neighborhood Hits	86	Shared Neighborhood Hits	56
SwissProt Accessions	P32019, Q5VSG9, Q5VSH0, Q5VSH1, Q658Q5, Q6P6D4, Q6PD53, Q86YE1	Gene names	INPP5B
Domain Architecture	No domain graphic available
Description	Type II inositol-1,4,5-trisphosphate 5-phosphatase precursor (EC 3.1.3.36) (Phosphoinositide 5-phosphatase) (5PTase) (75 kDa inositol polyphosphate-5-phosphatase).

OCRL_HUMAN
NC score	0.362415 (rank : 62)	θ value	3.77169e-06 (rank : 62)
Query Neighborhood Hits	376	Target Neighborhood Hits	77	Shared Neighborhood Hits	55
SwissProt Accessions	Q01968, O60800, Q15684, Q15774, Q5JQF1, Q5JQF2, Q9UJG5, Q9UMA5	Gene names	OCRL, INPP5F, OCRL1
Domain Architecture
Description	Inositol polyphosphate 5-phosphatase OCRL-1 (EC 3.1.3.36) (Lowe oculocerebrorenal syndrome protein).

PRP2_MOUSE
NC score	0.201088 (rank : 63)	θ value	θ > 10 (rank : 572)
Query Neighborhood Hits	376	Target Neighborhood Hits	347	Shared Neighborhood Hits	125
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

MUC7_HUMAN
NC score	0.189206 (rank : 64)	θ value	θ > 10 (rank : 524)
Query Neighborhood Hits	376	Target Neighborhood Hits	538	Shared Neighborhood Hits	163
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

PRP1_HUMAN
NC score	0.176221 (rank : 65)	θ value	θ > 10 (rank : 571)
Query Neighborhood Hits	376	Target Neighborhood Hits	385	Shared Neighborhood Hits	117
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PRR12_HUMAN
NC score	0.172673 (rank : 66)	θ value	θ > 10 (rank : 575)
Query Neighborhood Hits	376	Target Neighborhood Hits	460	Shared Neighborhood Hits	156
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

WASIP_HUMAN
NC score	0.171213 (rank : 67)	θ value	θ > 10 (rank : 684)
Query Neighborhood Hits	376	Target Neighborhood Hits	458	Shared Neighborhood Hits	156
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

GSCR1_HUMAN
NC score	0.169508 (rank : 68)	θ value	θ > 10 (rank : 494)
Query Neighborhood Hits	376	Target Neighborhood Hits	674	Shared Neighborhood Hits	173
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

WASIP_MOUSE
NC score	0.164645 (rank : 69)	θ value	θ > 10 (rank : 685)
Query Neighborhood Hits	376	Target Neighborhood Hits	392	Shared Neighborhood Hits	143
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

TAF4_HUMAN
NC score	0.163077 (rank : 70)	θ value	θ > 10 (rank : 647)
Query Neighborhood Hits	376	Target Neighborhood Hits	687	Shared Neighborhood Hits	162
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

PRG4_HUMAN
NC score	0.161806 (rank : 71)	θ value	θ > 10 (rank : 569)
Query Neighborhood Hits	376	Target Neighborhood Hits	764	Shared Neighborhood Hits	168
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SRRM1_MOUSE
NC score	0.160142 (rank : 72)	θ value	θ > 10 (rank : 634)
Query Neighborhood Hits	376	Target Neighborhood Hits	966	Shared Neighborhood Hits	173
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

PRB3_HUMAN
NC score	0.159628 (rank : 73)	θ value	θ > 10 (rank : 566)
Query Neighborhood Hits	376	Target Neighborhood Hits	318	Shared Neighborhood Hits	108
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

PRB4S_HUMAN
NC score	0.155060 (rank : 74)	θ value	θ > 10 (rank : 567)
Query Neighborhood Hits	376	Target Neighborhood Hits	330	Shared Neighborhood Hits	108
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

SRRM1_HUMAN
NC score	0.151825 (rank : 75)	θ value	θ > 10 (rank : 633)
Query Neighborhood Hits	376	Target Neighborhood Hits	690	Shared Neighborhood Hits	149
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

NACAM_MOUSE
NC score	0.151810 (rank : 76)	θ value	0.00035302 (rank : 72)
Query Neighborhood Hits	376	Target Neighborhood Hits	1866	Shared Neighborhood Hits	217
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

MBD6_HUMAN
NC score	0.151403 (rank : 77)	θ value	θ > 10 (rank : 513)
Query Neighborhood Hits	376	Target Neighborhood Hits	349	Shared Neighborhood Hits	125
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

MDC1_HUMAN
NC score	0.150330 (rank : 78)	θ value	1.87187e-05 (rank : 66)
Query Neighborhood Hits	376	Target Neighborhood Hits	1446	Shared Neighborhood Hits	165
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

RAPH1_HUMAN
NC score	0.147369 (rank : 79)	θ value	8.99809 (rank : 370)
Query Neighborhood Hits	376	Target Neighborhood Hits	593	Shared Neighborhood Hits	170
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

SRRM2_HUMAN
NC score	0.140948 (rank : 80)	θ value	4.03905 (rank : 299)
Query Neighborhood Hits	376	Target Neighborhood Hits	1296	Shared Neighborhood Hits	189
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

MDC1_MOUSE
NC score	0.140337 (rank : 81)	θ value	0.000786445 (rank : 78)
Query Neighborhood Hits	376	Target Neighborhood Hits	998	Shared Neighborhood Hits	138
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

WIRE_HUMAN
NC score	0.139268 (rank : 82)	θ value	θ > 10 (rank : 693)
Query Neighborhood Hits	376	Target Neighborhood Hits	329	Shared Neighborhood Hits	124
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

CS016_HUMAN
NC score	0.139216 (rank : 83)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	376	Target Neighborhood Hits	310	Shared Neighborhood Hits	116
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

BAT2_HUMAN
NC score	0.139007 (rank : 84)	θ value	6.88961 (rank : 316)
Query Neighborhood Hits	376	Target Neighborhood Hits	931	Shared Neighborhood Hits	181
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

PCLO_HUMAN
NC score	0.138561 (rank : 85)	θ value	0.00869519 (rank : 88)
Query Neighborhood Hits	376	Target Neighborhood Hits	2046	Shared Neighborhood Hits	237
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

CABIN_HUMAN
NC score	0.138197 (rank : 86)	θ value	0.000602161 (rank : 75)
Query Neighborhood Hits	376	Target Neighborhood Hits	490	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

BSN_MOUSE
NC score	0.134436 (rank : 87)	θ value	0.00509761 (rank : 85)
Query Neighborhood Hits	376	Target Neighborhood Hits	2057	Shared Neighborhood Hits	227
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

GGN_HUMAN
NC score	0.134091 (rank : 88)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	376	Target Neighborhood Hits	269	Shared Neighborhood Hits	106
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

PCLO_MOUSE
NC score	0.132817 (rank : 89)	θ value	0.0330416 (rank : 110)
Query Neighborhood Hits	376	Target Neighborhood Hits	2275	Shared Neighborhood Hits	235
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

SRRM2_MOUSE
NC score	0.132681 (rank : 90)	θ value	0.0736092 (rank : 118)
Query Neighborhood Hits	376	Target Neighborhood Hits	1470	Shared Neighborhood Hits	184
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

WIRE_MOUSE
NC score	0.132336 (rank : 91)	θ value	θ > 10 (rank : 694)
Query Neighborhood Hits	376	Target Neighborhood Hits	310	Shared Neighborhood Hits	124
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

SF3A2_MOUSE
NC score	0.132133 (rank : 92)	θ value	θ > 10 (rank : 609)
Query Neighborhood Hits	376	Target Neighborhood Hits	247	Shared Neighborhood Hits	97
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

ENAH_MOUSE
NC score	0.131883 (rank : 93)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	376	Target Neighborhood Hits	919	Shared Neighborhood Hits	183
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

SELPL_MOUSE
NC score	0.130818 (rank : 94)	θ value	0.00228821 (rank : 83)
Query Neighborhood Hits	376	Target Neighborhood Hits	588	Shared Neighborhood Hits	100
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

CN155_HUMAN
NC score	0.130496 (rank : 95)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	376	Target Neighborhood Hits	385	Shared Neighborhood Hits	104
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

PI5PA_HUMAN
NC score	0.130000 (rank : 96)	θ value	0.00869519 (rank : 89)
Query Neighborhood Hits	376	Target Neighborhood Hits	749	Shared Neighborhood Hits	135
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

CJ078_MOUSE
NC score	0.129426 (rank : 97)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	376	Target Neighborhood Hits	559	Shared Neighborhood Hits	123
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

BASP_MOUSE
NC score	0.128981 (rank : 98)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	376	Target Neighborhood Hits	260	Shared Neighborhood Hits	67
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

CN032_HUMAN
NC score	0.128777 (rank : 99)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	376	Target Neighborhood Hits	267	Shared Neighborhood Hits	99
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

GGN_MOUSE
NC score	0.127912 (rank : 100)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	376	Target Neighborhood Hits	311	Shared Neighborhood Hits	119
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

WBP11_HUMAN
NC score	0.127687 (rank : 101)	θ value	θ > 10 (rank : 690)
Query Neighborhood Hits	376	Target Neighborhood Hits	354	Shared Neighborhood Hits	106
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

SYNJ1_HUMAN
NC score	0.127419 (rank : 102)	θ value	4.03905 (rank : 300)
Query Neighborhood Hits	376	Target Neighborhood Hits	498	Shared Neighborhood Hits	144
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

SF3A2_HUMAN
NC score	0.126925 (rank : 103)	θ value	θ > 10 (rank : 608)
Query Neighborhood Hits	376	Target Neighborhood Hits	263	Shared Neighborhood Hits	93
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

PRG4_MOUSE
NC score	0.125615 (rank : 104)	θ value	θ > 10 (rank : 570)
Query Neighborhood Hits	376	Target Neighborhood Hits	624	Shared Neighborhood Hits	138
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SYNJ1_MOUSE
NC score	0.124793 (rank : 105)	θ value	0.21417 (rank : 140)
Query Neighborhood Hits	376	Target Neighborhood Hits	516	Shared Neighborhood Hits	149
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

YLPM1_MOUSE
NC score	0.124747 (rank : 106)	θ value	θ > 10 (rank : 696)
Query Neighborhood Hits	376	Target Neighborhood Hits	505	Shared Neighborhood Hits	150
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

TARSH_HUMAN
NC score	0.124696 (rank : 107)	θ value	0.0736092 (rank : 119)
Query Neighborhood Hits	376	Target Neighborhood Hits	768	Shared Neighborhood Hits	116
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

BSN_HUMAN
NC score	0.124361 (rank : 108)	θ value	8.99809 (rank : 355)
Query Neighborhood Hits	376	Target Neighborhood Hits	1537	Shared Neighborhood Hits	203
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CN032_MOUSE
NC score	0.124047 (rank : 109)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	376	Target Neighborhood Hits	233	Shared Neighborhood Hits	82
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

PI5PA_MOUSE
NC score	0.122732 (rank : 110)	θ value	θ > 10 (rank : 559)
Query Neighborhood Hits	376	Target Neighborhood Hits	331	Shared Neighborhood Hits	113
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

BASP_HUMAN
NC score	0.122485 (rank : 111)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	376	Target Neighborhood Hits	321	Shared Neighborhood Hits	84
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

ATN1_HUMAN
NC score	0.122392 (rank : 112)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	376	Target Neighborhood Hits	676	Shared Neighborhood Hits	147
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

OGFR_HUMAN
NC score	0.121677 (rank : 113)	θ value	1.43324e-05 (rank : 65)
Query Neighborhood Hits	376	Target Neighborhood Hits	1582	Shared Neighborhood Hits	159
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

WBP11_MOUSE
NC score	0.121038 (rank : 114)	θ value	θ > 10 (rank : 691)
Query Neighborhood Hits	376	Target Neighborhood Hits	362	Shared Neighborhood Hits	112
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

P85B_HUMAN
NC score	0.119419 (rank : 115)	θ value	0.365318 (rank : 163)
Query Neighborhood Hits	376	Target Neighborhood Hits	543	Shared Neighborhood Hits	62
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

RGS3_MOUSE
NC score	0.117976 (rank : 116)	θ value	2.88788e-06 (rank : 61)
Query Neighborhood Hits	376	Target Neighborhood Hits	1621	Shared Neighborhood Hits	162
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

RERE_HUMAN
NC score	0.117315 (rank : 117)	θ value	θ > 10 (rank : 587)
Query Neighborhood Hits	376	Target Neighborhood Hits	779	Shared Neighborhood Hits	165
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

PRRT3_HUMAN
NC score	0.116895 (rank : 118)	θ value	0.000270298 (rank : 69)
Query Neighborhood Hits	376	Target Neighborhood Hits	998	Shared Neighborhood Hits	121
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

MLL2_HUMAN
NC score	0.116354 (rank : 119)	θ value	6.88961 (rank : 332)
Query Neighborhood Hits	376	Target Neighborhood Hits	1788	Shared Neighborhood Hits	221
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MLL4_HUMAN
NC score	0.114953 (rank : 120)	θ value	θ > 10 (rank : 517)
Query Neighborhood Hits	376	Target Neighborhood Hits	722	Shared Neighborhood Hits	174
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

PRR13_HUMAN
NC score	0.114893 (rank : 121)	θ value	θ > 10 (rank : 576)
Query Neighborhood Hits	376	Target Neighborhood Hits	105	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

SMR3A_HUMAN
NC score	0.114516 (rank : 122)	θ value	θ > 10 (rank : 623)
Query Neighborhood Hits	376	Target Neighborhood Hits	93	Shared Neighborhood Hits	46
SwissProt Accessions	Q99954	Gene names	SMR3A, PBI, PROL5
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog A precursor (Proline-rich protein 5) (Proline-rich protein PBI).

ZN207_HUMAN
NC score	0.114063 (rank : 123)	θ value	θ > 10 (rank : 697)
Query Neighborhood Hits	376	Target Neighborhood Hits	326	Shared Neighborhood Hits	79
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

RERE_MOUSE
NC score	0.113979 (rank : 124)	θ value	θ > 10 (rank : 588)
Query Neighborhood Hits	376	Target Neighborhood Hits	785	Shared Neighborhood Hits	172
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

SH3G1_HUMAN
NC score	0.113680 (rank : 125)	θ value	9.29e-05 (rank : 68)
Query Neighborhood Hits	376	Target Neighborhood Hits	307	Shared Neighborhood Hits	33
SwissProt Accessions	Q99961, Q99668	Gene names	SH3GL1, CNSA1, SH3D2B
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL).

SH3G2_MOUSE
NC score	0.113190 (rank : 126)	θ value	0.000270298 (rank : 70)
Query Neighborhood Hits	376	Target Neighborhood Hits	319	Shared Neighborhood Hits	35
SwissProt Accessions	Q62420	Gene names	Sh3gl2, Sh3d2a
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (SH3p4).

CIC_HUMAN
NC score	0.111138 (rank : 127)	θ value	0.125558 (rank : 126)
Query Neighborhood Hits	376	Target Neighborhood Hits	992	Shared Neighborhood Hits	159
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

SH3G2_HUMAN
NC score	0.111114 (rank : 128)	θ value	0.000602161 (rank : 77)
Query Neighborhood Hits	376	Target Neighborhood Hits	324	Shared Neighborhood Hits	33
SwissProt Accessions	Q99962, Q9NQK5	Gene names	SH3GL2, CNSA2, SH3D2A
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (EEN-B1).

MUC1_HUMAN
NC score	0.111005 (rank : 129)	θ value	8.97725e-08 (rank : 56)
Query Neighborhood Hits	376	Target Neighborhood Hits	975	Shared Neighborhood Hits	127
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

MUC2_HUMAN
NC score	0.110349 (rank : 130)	θ value	θ > 10 (rank : 523)
Query Neighborhood Hits	376	Target Neighborhood Hits	906	Shared Neighborhood Hits	172
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

SH3G1_MOUSE
NC score	0.110310 (rank : 131)	θ value	0.00134147 (rank : 80)
Query Neighborhood Hits	376	Target Neighborhood Hits	291	Shared Neighborhood Hits	33
SwissProt Accessions	Q62419	Gene names	Sh3gl1, Sh3d2b
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (SH3p8).

WASL_MOUSE
NC score	0.110016 (rank : 132)	θ value	θ > 10 (rank : 687)
Query Neighborhood Hits	376	Target Neighborhood Hits	339	Shared Neighborhood Hits	125
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

CPSF6_MOUSE
NC score	0.109425 (rank : 133)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	376	Target Neighborhood Hits	356	Shared Neighborhood Hits	95
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

BAT2_MOUSE
NC score	0.108533 (rank : 134)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	376	Target Neighborhood Hits	947	Shared Neighborhood Hits	171
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

ALEX_HUMAN
NC score	0.108007 (rank : 135)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	376	Target Neighborhood Hits	361	Shared Neighborhood Hits	103
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

CPSF6_HUMAN
NC score	0.107849 (rank : 136)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	376	Target Neighborhood Hits	359	Shared Neighborhood Hits	93
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

SYN1_HUMAN
NC score	0.106603 (rank : 137)	θ value	θ > 10 (rank : 639)
Query Neighborhood Hits	376	Target Neighborhood Hits	419	Shared Neighborhood Hits	140
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

SET1A_HUMAN
NC score	0.106556 (rank : 138)	θ value	θ > 10 (rank : 605)
Query Neighborhood Hits	376	Target Neighborhood Hits	690	Shared Neighborhood Hits	143
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

NOLC1_HUMAN
NC score	0.105799 (rank : 139)	θ value	θ > 10 (rank : 542)
Query Neighborhood Hits	376	Target Neighborhood Hits	452	Shared Neighborhood Hits	76
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

MARCS_HUMAN
NC score	0.105480 (rank : 140)	θ value	θ > 10 (rank : 510)
Query Neighborhood Hits	376	Target Neighborhood Hits	204	Shared Neighborhood Hits	65
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

SHLB2_HUMAN
NC score	0.105433 (rank : 141)	θ value	0.00134147 (rank : 81)
Query Neighborhood Hits	376	Target Neighborhood Hits	86	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NR46, Q8WY61, Q96JH9	Gene names	SH3GLB2, KIAA1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

SHLB2_MOUSE
NC score	0.105175 (rank : 142)	θ value	0.00175202 (rank : 82)
Query Neighborhood Hits	376	Target Neighborhood Hits	88	Shared Neighborhood Hits	21
SwissProt Accessions	Q8R3V5, Q8K140, Q91ZI7	Gene names	Sh3glb2, Kiaa1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

CK024_HUMAN
NC score	0.104629 (rank : 143)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	376	Target Neighborhood Hits	408	Shared Neighborhood Hits	89
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

T22D2_HUMAN
NC score	0.104446 (rank : 144)	θ value	θ > 10 (rank : 645)
Query Neighborhood Hits	376	Target Neighborhood Hits	250	Shared Neighborhood Hits	87
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

TCOF_MOUSE
NC score	0.104190 (rank : 145)	θ value	θ > 10 (rank : 653)
Query Neighborhood Hits	376	Target Neighborhood Hits	471	Shared Neighborhood Hits	86
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

WASF2_MOUSE
NC score	0.103731 (rank : 146)	θ value	θ > 10 (rank : 680)
Query Neighborhood Hits	376	Target Neighborhood Hits	315	Shared Neighborhood Hits	125
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

CDN1C_HUMAN
NC score	0.103406 (rank : 147)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	376	Target Neighborhood Hits	168	Shared Neighborhood Hits	75
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

SFPQ_MOUSE
NC score	0.102636 (rank : 148)	θ value	θ > 10 (rank : 611)
Query Neighborhood Hits	376	Target Neighborhood Hits	958	Shared Neighborhood Hits	167
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

WASL_HUMAN
NC score	0.102410 (rank : 149)	θ value	θ > 10 (rank : 686)
Query Neighborhood Hits	376	Target Neighborhood Hits	312	Shared Neighborhood Hits	114
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

SON_HUMAN
NC score	0.102101 (rank : 150)	θ value	0.000461057 (rank : 74)
Query Neighborhood Hits	376	Target Neighborhood Hits	1568	Shared Neighborhood Hits	170
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

NCOA6_HUMAN
NC score	0.101666 (rank : 151)	θ value	0.0961366 (rank : 123)
Query Neighborhood Hits	376	Target Neighborhood Hits	1202	Shared Neighborhood Hits	172
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

SH3G3_HUMAN
NC score	0.100698 (rank : 152)	θ value	0.125558 (rank : 129)
Query Neighborhood Hits	376	Target Neighborhood Hits	222	Shared Neighborhood Hits	27
SwissProt Accessions	Q99963, O43553, O43554	Gene names	SH3GL3, CNSA3, SH3D2C
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (EEN-B2).

NCOA6_MOUSE
NC score	0.100379 (rank : 153)	θ value	0.62314 (rank : 182)
Query Neighborhood Hits	376	Target Neighborhood Hits	1076	Shared Neighborhood Hits	139
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

CCNK_MOUSE
NC score	0.100330 (rank : 154)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	376	Target Neighborhood Hits	350	Shared Neighborhood Hits	114
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

PELP1_MOUSE
NC score	0.100082 (rank : 155)	θ value	8.99809 (rank : 369)
Query Neighborhood Hits	376	Target Neighborhood Hits	709	Shared Neighborhood Hits	135
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

PO121_HUMAN
NC score	0.100069 (rank : 156)	θ value	θ > 10 (rank : 563)
Query Neighborhood Hits	376	Target Neighborhood Hits	344	Shared Neighborhood Hits	90
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

K1683_HUMAN
NC score	0.099301 (rank : 157)	θ value	0.47712 (rank : 170)
Query Neighborhood Hits	376	Target Neighborhood Hits	240	Shared Neighborhood Hits	46
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

SELV_HUMAN
NC score	0.099152 (rank : 158)	θ value	θ > 10 (rank : 604)
Query Neighborhood Hits	376	Target Neighborhood Hits	118	Shared Neighborhood Hits	55
SwissProt Accessions	P59797	Gene names	SELV
Domain Architecture	No domain graphic available
Description	Selenoprotein V.

PO121_MOUSE
NC score	0.098359 (rank : 159)	θ value	5.27518 (rank : 309)
Query Neighborhood Hits	376	Target Neighborhood Hits	345	Shared Neighborhood Hits	84
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

MAP4_MOUSE
NC score	0.097870 (rank : 160)	θ value	4.03905 (rank : 289)
Query Neighborhood Hits	376	Target Neighborhood Hits	409	Shared Neighborhood Hits	90
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

SMR1_MOUSE
NC score	0.096890 (rank : 161)	θ value	θ > 10 (rank : 622)
Query Neighborhood Hits	376	Target Neighborhood Hits	103	Shared Neighborhood Hits	54
SwissProt Accessions	Q61900	Gene names	Smr1, Msg1
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 1 precursor (Salivary protein MSG1).

SYN1_MOUSE
NC score	0.096889 (rank : 162)	θ value	θ > 10 (rank : 640)
Query Neighborhood Hits	376	Target Neighborhood Hits	363	Shared Neighborhood Hits	128
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

YLPM1_HUMAN
NC score	0.096461 (rank : 163)	θ value	θ > 10 (rank : 695)
Query Neighborhood Hits	376	Target Neighborhood Hits	670	Shared Neighborhood Hits	126
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

MUC1_MOUSE
NC score	0.096388 (rank : 164)	θ value	θ > 10 (rank : 522)
Query Neighborhood Hits	376	Target Neighborhood Hits	388	Shared Neighborhood Hits	65
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

NFH_MOUSE
NC score	0.096015 (rank : 165)	θ value	5.26297e-08 (rank : 55)
Query Neighborhood Hits	376	Target Neighborhood Hits	2247	Shared Neighborhood Hits	197
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

MILK1_MOUSE
NC score	0.095506 (rank : 166)	θ value	0.21417 (rank : 136)
Query Neighborhood Hits	376	Target Neighborhood Hits	788	Shared Neighborhood Hits	139
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

WASF4_HUMAN
NC score	0.095411 (rank : 167)	θ value	θ > 10 (rank : 683)
Query Neighborhood Hits	376	Target Neighborhood Hits	282	Shared Neighborhood Hits	117
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

ABI2_HUMAN
NC score	0.095380 (rank : 168)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	376	Target Neighborhood Hits	350	Shared Neighborhood Hits	84
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

K1802_HUMAN
NC score	0.094614 (rank : 169)	θ value	6.88961 (rank : 330)
Query Neighborhood Hits	376	Target Neighborhood Hits	1378	Shared Neighborhood Hits	175
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

CIC_MOUSE
NC score	0.093909 (rank : 170)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	376	Target Neighborhood Hits	742	Shared Neighborhood Hits	161
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

SFPQ_HUMAN
NC score	0.093871 (rank : 171)	θ value	θ > 10 (rank : 610)
Query Neighborhood Hits	376	Target Neighborhood Hits	986	Shared Neighborhood Hits	165
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

FMNL_HUMAN
NC score	0.093717 (rank : 172)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	376	Target Neighborhood Hits	529	Shared Neighborhood Hits	139
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

BAT3_MOUSE
NC score	0.093684 (rank : 173)	θ value	8.99809 (rank : 354)
Query Neighborhood Hits	376	Target Neighborhood Hits	518	Shared Neighborhood Hits	110
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

MARCS_MOUSE
NC score	0.093322 (rank : 174)	θ value	θ > 10 (rank : 511)
Query Neighborhood Hits	376	Target Neighborhood Hits	227	Shared Neighborhood Hits	59
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

MAP4_HUMAN
NC score	0.092936 (rank : 175)	θ value	1.81305 (rank : 230)
Query Neighborhood Hits	376	Target Neighborhood Hits	428	Shared Neighborhood Hits	84
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

PELP1_HUMAN
NC score	0.092454 (rank : 176)	θ value	θ > 10 (rank : 558)
Query Neighborhood Hits	376	Target Neighborhood Hits	596	Shared Neighborhood Hits	112
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

WASF2_HUMAN
NC score	0.092200 (rank : 177)	θ value	θ > 10 (rank : 679)
Query Neighborhood Hits	376	Target Neighborhood Hits	280	Shared Neighborhood Hits	107
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

RGS3_HUMAN
NC score	0.092126 (rank : 178)	θ value	0.000602161 (rank : 76)
Query Neighborhood Hits	376	Target Neighborhood Hits	1375	Shared Neighborhood Hits	131
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

SRBS1_HUMAN
NC score	0.091711 (rank : 179)	θ value	θ > 10 (rank : 630)
Query Neighborhood Hits	376	Target Neighborhood Hits	396	Shared Neighborhood Hits	67
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

MAGE1_HUMAN
NC score	0.091658 (rank : 180)	θ value	0.00035302 (rank : 71)
Query Neighborhood Hits	376	Target Neighborhood Hits	1389	Shared Neighborhood Hits	168
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

K1543_HUMAN
NC score	0.091108 (rank : 181)	θ value	0.0148317 (rank : 95)
Query Neighborhood Hits	376	Target Neighborhood Hits	435	Shared Neighborhood Hits	77
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

NU214_HUMAN
NC score	0.091002 (rank : 182)	θ value	θ > 10 (rank : 543)
Query Neighborhood Hits	376	Target Neighborhood Hits	657	Shared Neighborhood Hits	108
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

DGKK_HUMAN
NC score	0.090843 (rank : 183)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	376	Target Neighborhood Hits	378	Shared Neighborhood Hits	107
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

SH3G3_MOUSE
NC score	0.090826 (rank : 184)	θ value	θ > 10 (rank : 615)
Query Neighborhood Hits	376	Target Neighborhood Hits	236	Shared Neighborhood Hits	27
SwissProt Accessions	Q62421	Gene names	Sh3gl3, Sh3d2c, Sh3d2c2
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (SH3p13).

SRBS1_MOUSE
NC score	0.090617 (rank : 185)	θ value	2.36792 (rank : 257)
Query Neighborhood Hits	376	Target Neighborhood Hits	409	Shared Neighborhood Hits	64
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

PCQAP_HUMAN
NC score	0.090592 (rank : 186)	θ value	θ > 10 (rank : 550)
Query Neighborhood Hits	376	Target Neighborhood Hits	549	Shared Neighborhood Hits	105
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

SFR15_HUMAN
NC score	0.090436 (rank : 187)	θ value	θ > 10 (rank : 612)
Query Neighborhood Hits	376	Target Neighborhood Hits	368	Shared Neighborhood Hits	86
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

TCOF_HUMAN
NC score	0.090343 (rank : 188)	θ value	θ > 10 (rank : 652)
Query Neighborhood Hits	376	Target Neighborhood Hits	543	Shared Neighborhood Hits	91
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

BCL9_HUMAN
NC score	0.090160 (rank : 189)	θ value	0.279714 (rank : 141)
Query Neighborhood Hits	376	Target Neighborhood Hits	1008	Shared Neighborhood Hits	144
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

CBP_HUMAN
NC score	0.090049 (rank : 190)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	376	Target Neighborhood Hits	941	Shared Neighborhood Hits	181
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

K1543_MOUSE
NC score	0.089709 (rank : 191)	θ value	θ > 10 (rank : 505)
Query Neighborhood Hits	376	Target Neighborhood Hits	497	Shared Neighborhood Hits	87
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

TCRG1_MOUSE
NC score	0.089521 (rank : 192)	θ value	θ > 10 (rank : 655)
Query Neighborhood Hits	376	Target Neighborhood Hits	947	Shared Neighborhood Hits	122
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

HCLS1_MOUSE
NC score	0.089170 (rank : 193)	θ value	6.88961 (rank : 327)
Query Neighborhood Hits	376	Target Neighborhood Hits	329	Shared Neighborhood Hits	54
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

FMN2_HUMAN
NC score	0.089112 (rank : 194)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	376	Target Neighborhood Hits	484	Shared Neighborhood Hits	114
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

IASPP_HUMAN
NC score	0.088910 (rank : 195)	θ value	θ > 10 (rank : 496)
Query Neighborhood Hits	376	Target Neighborhood Hits	688	Shared Neighborhood Hits	109
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

PRR13_MOUSE
NC score	0.088056 (rank : 196)	θ value	θ > 10 (rank : 577)
Query Neighborhood Hits	376	Target Neighborhood Hits	54	Shared Neighborhood Hits	24
SwissProt Accessions	Q9CQJ5, Q3U3U4	Gene names	Prr13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

IASPP_MOUSE
NC score	0.087928 (rank : 197)	θ value	0.125558 (rank : 127)
Query Neighborhood Hits	376	Target Neighborhood Hits	1024	Shared Neighborhood Hits	122
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

BRD4_MOUSE
NC score	0.087393 (rank : 198)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	376	Target Neighborhood Hits	845	Shared Neighborhood Hits	159
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

HCLS1_HUMAN
NC score	0.087278 (rank : 199)	θ value	θ > 10 (rank : 495)
Query Neighborhood Hits	376	Target Neighborhood Hits	358	Shared Neighborhood Hits	61
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

NCOR2_HUMAN
NC score	0.086527 (rank : 200)	θ value	3.0926 (rank : 273)
Query Neighborhood Hits	376	Target Neighborhood Hits	870	Shared Neighborhood Hits	151
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

BCL9_MOUSE
NC score	0.086487 (rank : 201)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	376	Target Neighborhood Hits	770	Shared Neighborhood Hits	128
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

BAG3_MOUSE
NC score	0.086476 (rank : 202)	θ value	4.03905 (rank : 282)
Query Neighborhood Hits	376	Target Neighborhood Hits	513	Shared Neighborhood Hits	109
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

TCRG1_HUMAN
NC score	0.085884 (rank : 203)	θ value	θ > 10 (rank : 654)
Query Neighborhood Hits	376	Target Neighborhood Hits	929	Shared Neighborhood Hits	113
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

K1802_MOUSE
NC score	0.085576 (rank : 204)	θ value	0.00665767 (rank : 86)
Query Neighborhood Hits	376	Target Neighborhood Hits	1596	Shared Neighborhood Hits	163
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MADCA_HUMAN
NC score	0.085170 (rank : 205)	θ value	θ > 10 (rank : 508)
Query Neighborhood Hits	376	Target Neighborhood Hits	221	Shared Neighborhood Hits	77
SwissProt Accessions	Q13477, O60222, O75867	Gene names	MADCAM1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (hMAdCAM-1).

RPB1_MOUSE
NC score	0.084693 (rank : 206)	θ value	θ > 10 (rank : 592)
Query Neighborhood Hits	376	Target Neighborhood Hits	363	Shared Neighborhood Hits	101
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

SF01_HUMAN
NC score	0.084497 (rank : 207)	θ value	θ > 10 (rank : 606)
Query Neighborhood Hits	376	Target Neighborhood Hits	287	Shared Neighborhood Hits	92
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

P85B_MOUSE
NC score	0.084181 (rank : 208)	θ value	6.88961 (rank : 336)
Query Neighborhood Hits	376	Target Neighborhood Hits	519	Shared Neighborhood Hits	47
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

WBS14_HUMAN
NC score	0.083954 (rank : 209)	θ value	θ > 10 (rank : 692)
Query Neighborhood Hits	376	Target Neighborhood Hits	273	Shared Neighborhood Hits	91
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

MBB1A_HUMAN
NC score	0.083886 (rank : 210)	θ value	0.0193708 (rank : 101)
Query Neighborhood Hits	376	Target Neighborhood Hits	665	Shared Neighborhood Hits	81
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

CBP_MOUSE
NC score	0.083649 (rank : 211)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	376	Target Neighborhood Hits	1051	Shared Neighborhood Hits	177
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

RPB1_HUMAN
NC score	0.083441 (rank : 212)	θ value	θ > 10 (rank : 591)
Query Neighborhood Hits	376	Target Neighborhood Hits	362	Shared Neighborhood Hits	100
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RTP3_MOUSE
NC score	0.083327 (rank : 213)	θ value	0.0961366 (rank : 125)
Query Neighborhood Hits	376	Target Neighborhood Hits	374	Shared Neighborhood Hits	66
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

ALEX_MOUSE
NC score	0.083047 (rank : 214)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	376	Target Neighborhood Hits	197	Shared Neighborhood Hits	72
SwissProt Accessions	Q6R0H6, Q8BIR3	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

WASF1_MOUSE
NC score	0.082989 (rank : 215)	θ value	θ > 10 (rank : 678)
Query Neighborhood Hits	376	Target Neighborhood Hits	261	Shared Neighborhood Hits	103
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

PRPC_HUMAN
NC score	0.082581 (rank : 216)	θ value	θ > 10 (rank : 574)
Query Neighborhood Hits	376	Target Neighborhood Hits	165	Shared Neighborhood Hits	50
SwissProt Accessions	P02810, Q4VBP2, Q53XA2, Q6P2F6	Gene names	PRH1
Domain Architecture	No domain graphic available
Description	Salivary acidic proline-rich phosphoprotein 1/2 precursor (PRP-1/PRP- 2) (Parotid proline-rich protein 1/2) (Pr1/Pr2) (Protein C) (Parotid acidic protein) (Pa) (Parotid isoelectric focusing variant protein) (PIF-S) (Parotid double-band protein) (Db-s) [Contains: Salivary acidic proline-rich phosphoprotein 1/2; Salivary acidic proline-rich phosphoprotein 3/4 (PRP-3/PRP-4) (Protein A) (PIF-F) (Db-F); Peptide P-C].

SON_MOUSE
NC score	0.082449 (rank : 217)	θ value	θ > 10 (rank : 627)
Query Neighborhood Hits	376	Target Neighborhood Hits	957	Shared Neighborhood Hits	127
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

WASF1_HUMAN
NC score	0.082332 (rank : 218)	θ value	θ > 10 (rank : 677)
Query Neighborhood Hits	376	Target Neighborhood Hits	260	Shared Neighborhood Hits	104
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

MLL3_HUMAN
NC score	0.082234 (rank : 219)	θ value	0.47712 (rank : 172)
Query Neighborhood Hits	376	Target Neighborhood Hits	1644	Shared Neighborhood Hits	165
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

EP300_HUMAN
NC score	0.081824 (rank : 220)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	376	Target Neighborhood Hits	821	Shared Neighborhood Hits	148
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

GRIN1_HUMAN
NC score	0.081738 (rank : 221)	θ value	0.0961366 (rank : 122)
Query Neighborhood Hits	376	Target Neighborhood Hits	681	Shared Neighborhood Hits	97
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

RP1L1_HUMAN
NC score	0.081553 (rank : 222)	θ value	0.279714 (rank : 149)
Query Neighborhood Hits	376	Target Neighborhood Hits	1072	Shared Neighborhood Hits	118
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

MINT_MOUSE
NC score	0.081421 (rank : 223)	θ value	1.81305 (rank : 231)
Query Neighborhood Hits	376	Target Neighborhood Hits	1514	Shared Neighborhood Hits	164
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

GRIN1_MOUSE
NC score	0.080476 (rank : 224)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	376	Target Neighborhood Hits	337	Shared Neighborhood Hits	82
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

TAU_MOUSE
NC score	0.079605 (rank : 225)	θ value	0.62314 (rank : 184)
Query Neighborhood Hits	376	Target Neighborhood Hits	502	Shared Neighborhood Hits	87
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

EFS_HUMAN
NC score	0.079127 (rank : 226)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	376	Target Neighborhood Hits	348	Shared Neighborhood Hits	70
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

DDEF2_HUMAN
NC score	0.078960 (rank : 227)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	376	Target Neighborhood Hits	599	Shared Neighborhood Hits	91
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

MLL3_MOUSE
NC score	0.078922 (rank : 228)	θ value	0.0252991 (rank : 105)
Query Neighborhood Hits	376	Target Neighborhood Hits	1399	Shared Neighborhood Hits	155
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MUCDL_HUMAN
NC score	0.078780 (rank : 229)	θ value	2.36792 (rank : 252)
Query Neighborhood Hits	376	Target Neighborhood Hits	777	Shared Neighborhood Hits	111
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

SGIP1_HUMAN
NC score	0.078726 (rank : 230)	θ value	θ > 10 (rank : 613)
Query Neighborhood Hits	376	Target Neighborhood Hits	198	Shared Neighborhood Hits	72
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

PCQAP_MOUSE
NC score	0.078653 (rank : 231)	θ value	θ > 10 (rank : 551)
Query Neighborhood Hits	376	Target Neighborhood Hits	506	Shared Neighborhood Hits	103
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

MUC13_MOUSE
NC score	0.078423 (rank : 232)	θ value	θ > 10 (rank : 521)
Query Neighborhood Hits	376	Target Neighborhood Hits	447	Shared Neighborhood Hits	75
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

SH3K1_MOUSE
NC score	0.078420 (rank : 233)	θ value	θ > 10 (rank : 617)
Query Neighborhood Hits	376	Target Neighborhood Hits	332	Shared Neighborhood Hits	50
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

DDEF2_MOUSE
NC score	0.078320 (rank : 234)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	376	Target Neighborhood Hits	625	Shared Neighborhood Hits	89
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

VINEX_MOUSE
NC score	0.078119 (rank : 235)	θ value	θ > 10 (rank : 676)
Query Neighborhood Hits	376	Target Neighborhood Hits	286	Shared Neighborhood Hits	45
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

CNOT3_HUMAN
NC score	0.077968 (rank : 236)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	376	Target Neighborhood Hits	425	Shared Neighborhood Hits	88
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

VINEX_HUMAN
NC score	0.077655 (rank : 237)	θ value	θ > 10 (rank : 675)
Query Neighborhood Hits	376	Target Neighborhood Hits	270	Shared Neighborhood Hits	48
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

BAG3_HUMAN
NC score	0.077517 (rank : 238)	θ value	4.03905 (rank : 281)
Query Neighborhood Hits	376	Target Neighborhood Hits	314	Shared Neighborhood Hits	75
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

TXND2_HUMAN
NC score	0.077462 (rank : 239)	θ value	0.0252991 (rank : 106)
Query Neighborhood Hits	376	Target Neighborhood Hits	793	Shared Neighborhood Hits	81
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

BRD4_HUMAN
NC score	0.076761 (rank : 240)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	376	Target Neighborhood Hits	851	Shared Neighborhood Hits	151
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

SAPS1_HUMAN
NC score	0.076652 (rank : 241)	θ value	0.125558 (rank : 128)
Query Neighborhood Hits	376	Target Neighborhood Hits	704	Shared Neighborhood Hits	109
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

ARI1A_HUMAN
NC score	0.076554 (rank : 242)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	376	Target Neighborhood Hits	787	Shared Neighborhood Hits	132
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

NELFA_MOUSE
NC score	0.075959 (rank : 243)	θ value	θ > 10 (rank : 538)
Query Neighborhood Hits	376	Target Neighborhood Hits	195	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BG30, Q8BVE4, Q8VEI7, Q9CSJ9, Q9Z1V9	Gene names	Whsc2, Nelfa, Whsc2h
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 homolog) (mWHSC2).

ASPP1_MOUSE
NC score	0.075849 (rank : 244)	θ value	0.21417 (rank : 133)
Query Neighborhood Hits	376	Target Neighborhood Hits	1244	Shared Neighborhood Hits	138
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

CSKI1_HUMAN
NC score	0.075594 (rank : 245)	θ value	4.03905 (rank : 284)
Query Neighborhood Hits	376	Target Neighborhood Hits	997	Shared Neighborhood Hits	157
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

IF4G1_HUMAN
NC score	0.075362 (rank : 246)	θ value	0.62314 (rank : 181)
Query Neighborhood Hits	376	Target Neighborhood Hits	347	Shared Neighborhood Hits	92
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

SYP2L_HUMAN
NC score	0.075314 (rank : 247)	θ value	θ > 10 (rank : 643)
Query Neighborhood Hits	376	Target Neighborhood Hits	400	Shared Neighborhood Hits	102
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

PCTL_MOUSE
NC score	0.075273 (rank : 248)	θ value	θ > 10 (rank : 553)
Query Neighborhood Hits	376	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JMD3	Gene names	Stard10, Pctpl, Sdccag28, Sdccagg28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28 homolog).

GRP3_HUMAN
NC score	0.075117 (rank : 249)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	376	Target Neighborhood Hits	131	Shared Neighborhood Hits	14
SwissProt Accessions	Q8IV61, O94931	Gene names	RASGRP3, GRP3, KIAA0846
Domain Architecture
Description	RAS guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1).

SH3K1_HUMAN
NC score	0.075068 (rank : 250)	θ value	θ > 10 (rank : 616)
Query Neighborhood Hits	376	Target Neighborhood Hits	341	Shared Neighborhood Hits	46
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

IF35_MOUSE
NC score	0.074905 (rank : 251)	θ value	θ > 10 (rank : 498)
Query Neighborhood Hits	376	Target Neighborhood Hits	210	Shared Neighborhood Hits	80
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

WASP_HUMAN
NC score	0.074621 (rank : 252)	θ value	θ > 10 (rank : 688)
Query Neighborhood Hits	376	Target Neighborhood Hits	195	Shared Neighborhood Hits	88
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

TMAP1_HUMAN
NC score	0.074620 (rank : 253)	θ value	θ > 10 (rank : 660)
Query Neighborhood Hits	376	Target Neighborhood Hits	140	Shared Neighborhood Hits	44
SwissProt Accessions	P84157	Gene names	TMAP1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

NELFA_HUMAN
NC score	0.074512 (rank : 254)	θ value	θ > 10 (rank : 537)
Query Neighborhood Hits	376	Target Neighborhood Hits	161	Shared Neighborhood Hits	75
SwissProt Accessions	Q9H3P2, O95392	Gene names	WHSC2, NELFA
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 protein).

TAU_HUMAN
NC score	0.074462 (rank : 255)	θ value	θ > 10 (rank : 650)
Query Neighborhood Hits	376	Target Neighborhood Hits	448	Shared Neighborhood Hits	87
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

PCTL_HUMAN
NC score	0.074413 (rank : 256)	θ value	θ > 10 (rank : 552)
Query Neighborhood Hits	376	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y365, O60532	Gene names	STARD10, SDCCAG28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28) (Antigen NY-CO-28).

3BP2_HUMAN
NC score	0.074242 (rank : 257)	θ value	1.06291 (rank : 199)
Query Neighborhood Hits	376	Target Neighborhood Hits	296	Shared Neighborhood Hits	52
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

MILK1_HUMAN
NC score	0.074207 (rank : 258)	θ value	θ > 10 (rank : 514)
Query Neighborhood Hits	376	Target Neighborhood Hits	427	Shared Neighborhood Hits	103
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

NCK2_HUMAN
NC score	0.074193 (rank : 259)	θ value	θ > 10 (rank : 535)
Query Neighborhood Hits	376	Target Neighborhood Hits	310	Shared Neighborhood Hits	39
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

FMN2_MOUSE
NC score	0.074175 (rank : 260)	θ value	2.36792 (rank : 245)
Query Neighborhood Hits	376	Target Neighborhood Hits	349	Shared Neighborhood Hits	90
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

CENB2_HUMAN
NC score	0.074156 (rank : 261)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	376	Target Neighborhood Hits	425	Shared Neighborhood Hits	30
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

ASPP1_HUMAN
NC score	0.073884 (rank : 262)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	376	Target Neighborhood Hits	956	Shared Neighborhood Hits	111
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

MINT_HUMAN
NC score	0.073870 (rank : 263)	θ value	θ > 10 (rank : 515)
Query Neighborhood Hits	376	Target Neighborhood Hits	1291	Shared Neighborhood Hits	158
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

LCP2_HUMAN
NC score	0.073557 (rank : 264)	θ value	0.0252991 (rank : 104)
Query Neighborhood Hits	376	Target Neighborhood Hits	531	Shared Neighborhood Hits	82
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

SHLB1_HUMAN
NC score	0.073415 (rank : 265)	θ value	θ > 10 (rank : 619)
Query Neighborhood Hits	376	Target Neighborhood Hits	96	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y371, Q9H3Z0, Q9NR47, Q9NYA9	Gene names	SH3GLB1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1) (Bax- interacting factor 1) (Bif-1).

PRP5_HUMAN
NC score	0.073155 (rank : 266)	θ value	θ > 10 (rank : 573)
Query Neighborhood Hits	376	Target Neighborhood Hits	108	Shared Neighborhood Hits	35
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

WASP_MOUSE
NC score	0.073127 (rank : 267)	θ value	θ > 10 (rank : 689)
Query Neighborhood Hits	376	Target Neighborhood Hits	223	Shared Neighborhood Hits	86
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

CRTC1_HUMAN
NC score	0.073087 (rank : 268)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	376	Target Neighborhood Hits	319	Shared Neighborhood Hits	88
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

SHLB1_MOUSE
NC score	0.072945 (rank : 269)	θ value	θ > 10 (rank : 620)
Query Neighborhood Hits	376	Target Neighborhood Hits	101	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JK48, Q8CDS9, Q8VI52, Q9CT31	Gene names	Sh3glb1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1).

CSKI1_MOUSE
NC score	0.072858 (rank : 270)	θ value	0.0113563 (rank : 91)
Query Neighborhood Hits	376	Target Neighborhood Hits	1031	Shared Neighborhood Hits	162
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

SGIP1_MOUSE
NC score	0.072791 (rank : 271)	θ value	θ > 10 (rank : 614)
Query Neighborhood Hits	376	Target Neighborhood Hits	180	Shared Neighborhood Hits	66
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SC24C_HUMAN
NC score	0.072607 (rank : 272)	θ value	0.21417 (rank : 137)
Query Neighborhood Hits	376	Target Neighborhood Hits	662	Shared Neighborhood Hits	94
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

CSF1_HUMAN
NC score	0.072533 (rank : 273)	θ value	0.0148317 (rank : 93)
Query Neighborhood Hits	376	Target Neighborhood Hits	258	Shared Neighborhood Hits	47
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

GRAP_HUMAN
NC score	0.072349 (rank : 274)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	376	Target Neighborhood Hits	307	Shared Neighborhood Hits	37
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

DDEF1_MOUSE
NC score	0.072234 (rank : 275)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	376	Target Neighborhood Hits	592	Shared Neighborhood Hits	76
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

SYNPO_HUMAN
NC score	0.072066 (rank : 276)	θ value	0.279714 (rank : 152)
Query Neighborhood Hits	376	Target Neighborhood Hits	281	Shared Neighborhood Hits	64
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

MNT_HUMAN
NC score	0.072058 (rank : 277)	θ value	θ > 10 (rank : 519)
Query Neighborhood Hits	376	Target Neighborhood Hits	496	Shared Neighborhood Hits	108
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

GRB2_HUMAN
NC score	0.071936 (rank : 278)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	376	Target Neighborhood Hits	310	Shared Neighborhood Hits	34
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

MNT_MOUSE
NC score	0.071924 (rank : 279)	θ value	θ > 10 (rank : 520)
Query Neighborhood Hits	376	Target Neighborhood Hits	432	Shared Neighborhood Hits	97
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

GRB2_MOUSE
NC score	0.071915 (rank : 280)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	376	Target Neighborhood Hits	312	Shared Neighborhood Hits	34
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

NCF4_MOUSE
NC score	0.071552 (rank : 281)	θ value	θ > 10 (rank : 533)
Query Neighborhood Hits	376	Target Neighborhood Hits	177	Shared Neighborhood Hits	20
SwissProt Accessions	P97369	Gene names	Ncf4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

TM108_MOUSE
NC score	0.071342 (rank : 282)	θ value	θ > 10 (rank : 659)
Query Neighborhood Hits	376	Target Neighborhood Hits	336	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

GRAP_MOUSE
NC score	0.070950 (rank : 283)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	376	Target Neighborhood Hits	309	Shared Neighborhood Hits	39
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

SELPL_HUMAN
NC score	0.070634 (rank : 284)	θ value	θ > 10 (rank : 603)
Query Neighborhood Hits	376	Target Neighborhood Hits	68	Shared Neighborhood Hits	24
SwissProt Accessions	Q14242, Q12775	Gene names	SELPLG
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand) (CD162 antigen).

BAT3_HUMAN
NC score	0.070574 (rank : 285)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	376	Target Neighborhood Hits	490	Shared Neighborhood Hits	89
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

CD2AP_HUMAN
NC score	0.070553 (rank : 286)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	376	Target Neighborhood Hits	315	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

CS007_MOUSE
NC score	0.070487 (rank : 287)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	376	Target Neighborhood Hits	464	Shared Neighborhood Hits	96
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

SMOO_HUMAN
NC score	0.070468 (rank : 288)	θ value	θ > 10 (rank : 621)
Query Neighborhood Hits	376	Target Neighborhood Hits	391	Shared Neighborhood Hits	97
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

SF01_MOUSE
NC score	0.070153 (rank : 289)	θ value	θ > 10 (rank : 607)
Query Neighborhood Hits	376	Target Neighborhood Hits	240	Shared Neighborhood Hits	70
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

ABI2_MOUSE
NC score	0.069985 (rank : 290)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	376	Target Neighborhood Hits	266	Shared Neighborhood Hits	45
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

CO039_HUMAN
NC score	0.069840 (rank : 291)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	376	Target Neighborhood Hits	264	Shared Neighborhood Hits	77
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

DOT1L_HUMAN
NC score	0.069386 (rank : 292)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	376	Target Neighborhood Hits	660	Shared Neighborhood Hits	104
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

DMRTD_MOUSE
NC score	0.069107 (rank : 293)	θ value	0.0113563 (rank : 92)
Query Neighborhood Hits	376	Target Neighborhood Hits	72	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CGW9	Gene names	Dmrtc2, Dmrt7
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2 (Doublesex- and mab-3-related transcription factor 7).

FMN1B_MOUSE
NC score	0.068578 (rank : 294)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	376	Target Neighborhood Hits	447	Shared Neighborhood Hits	114
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

AB1IP_HUMAN
NC score	0.068503 (rank : 295)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	376	Target Neighborhood Hits	213	Shared Neighborhood Hits	76
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

PS1C2_HUMAN
NC score	0.068464 (rank : 296)	θ value	θ > 10 (rank : 580)
Query Neighborhood Hits	376	Target Neighborhood Hits	66	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UIG4	Gene names	PSORS1C2, C6orf17, SPR1
Domain Architecture	No domain graphic available
Description	Psoriasis susceptibility 1 candidate gene 2 protein precursor (SPR1 protein).

CNOT3_MOUSE
NC score	0.068431 (rank : 297)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	376	Target Neighborhood Hits	504	Shared Neighborhood Hits	97
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

NCF4_HUMAN
NC score	0.068421 (rank : 298)	θ value	θ > 10 (rank : 532)
Query Neighborhood Hits	376	Target Neighborhood Hits	161	Shared Neighborhood Hits	18
SwissProt Accessions	Q15080, O60808, Q86U56, Q9BU98, Q9NP45	Gene names	NCF4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

CRSP2_HUMAN
NC score	0.068410 (rank : 299)	θ value	1.06291 (rank : 201)
Query Neighborhood Hits	376	Target Neighborhood Hits	380	Shared Neighborhood Hits	67
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

CD2AP_MOUSE
NC score	0.068335 (rank : 300)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	376	Target Neighborhood Hits	336	Shared Neighborhood Hits	59
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

CF150_HUMAN
NC score	0.068305 (rank : 301)	θ value	0.62314 (rank : 178)
Query Neighborhood Hits	376	Target Neighborhood Hits	96	Shared Neighborhood Hits	22
SwissProt Accessions	Q8N884, Q32NC9, Q5SWL0, Q5SWL1, Q96E45	Gene names	C6orf150
Domain Architecture	No domain graphic available
Description	Protein C6orf150.

PDZD8_HUMAN
NC score	0.068154 (rank : 302)	θ value	θ > 10 (rank : 557)
Query Neighborhood Hits	376	Target Neighborhood Hits	185	Shared Neighborhood Hits	34
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

CENB5_HUMAN
NC score	0.068085 (rank : 303)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	376	Target Neighborhood Hits	395	Shared Neighborhood Hits	22
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

AFF1_HUMAN
NC score	0.068057 (rank : 304)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	376	Target Neighborhood Hits	506	Shared Neighborhood Hits	86
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

CENB1_HUMAN
NC score	0.067733 (rank : 305)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	376	Target Neighborhood Hits	383	Shared Neighborhood Hits	26
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

ARI1B_HUMAN
NC score	0.067697 (rank : 306)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	376	Target Neighborhood Hits	567	Shared Neighborhood Hits	105
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

DMRTD_HUMAN
NC score	0.067656 (rank : 307)	θ value	0.0330416 (rank : 107)
Query Neighborhood Hits	376	Target Neighborhood Hits	216	Shared Neighborhood Hits	34
SwissProt Accessions	Q8IXT2, Q8N6Q2, Q96M39, Q96SD4	Gene names	DMRTC2
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2.

MAP1A_HUMAN
NC score	0.067571 (rank : 308)	θ value	0.0736092 (rank : 116)
Query Neighborhood Hits	376	Target Neighborhood Hits	1626	Shared Neighborhood Hits	149
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

HRX_HUMAN
NC score	0.067512 (rank : 309)	θ value	8.99809 (rank : 363)
Query Neighborhood Hits	376	Target Neighborhood Hits	825	Shared Neighborhood Hits	115
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

MUCDL_MOUSE
NC score	0.067344 (rank : 310)	θ value	1.81305 (rank : 232)
Query Neighborhood Hits	376	Target Neighborhood Hits	461	Shared Neighborhood Hits	88
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

PDZD2_HUMAN
NC score	0.067085 (rank : 311)	θ value	0.000461057 (rank : 73)
Query Neighborhood Hits	376	Target Neighborhood Hits	772	Shared Neighborhood Hits	89
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

ITSN1_HUMAN
NC score	0.067079 (rank : 312)	θ value	1.38821 (rank : 222)
Query Neighborhood Hits	376	Target Neighborhood Hits	1757	Shared Neighborhood Hits	123
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

MYO15_HUMAN
NC score	0.066761 (rank : 313)	θ value	θ > 10 (rank : 526)
Query Neighborhood Hits	376	Target Neighborhood Hits	671	Shared Neighborhood Hits	123
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

BCAR1_MOUSE
NC score	0.066756 (rank : 314)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	376	Target Neighborhood Hits	438	Shared Neighborhood Hits	77
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

TARA_HUMAN
NC score	0.066255 (rank : 315)	θ value	θ > 10 (rank : 648)
Query Neighborhood Hits	376	Target Neighborhood Hits	1626	Shared Neighborhood Hits	157
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

MUC5B_HUMAN
NC score	0.066077 (rank : 316)	θ value	2.36792 (rank : 251)
Query Neighborhood Hits	376	Target Neighborhood Hits	1020	Shared Neighborhood Hits	123
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

STAC_MOUSE
NC score	0.066033 (rank : 317)	θ value	θ > 10 (rank : 638)
Query Neighborhood Hits	376	Target Neighborhood Hits	268	Shared Neighborhood Hits	31
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

CSKI2_HUMAN
NC score	0.065899 (rank : 318)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	376	Target Neighborhood Hits	747	Shared Neighborhood Hits	135
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

FMN1A_MOUSE
NC score	0.065778 (rank : 319)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	376	Target Neighborhood Hits	423	Shared Neighborhood Hits	111
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

ATX2L_HUMAN
NC score	0.065571 (rank : 320)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	376	Target Neighborhood Hits	443	Shared Neighborhood Hits	89
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

VCX3_HUMAN
NC score	0.065038 (rank : 321)	θ value	θ > 10 (rank : 673)
Query Neighborhood Hits	376	Target Neighborhood Hits	105	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NNX9, Q9P0H4	Gene names	VCX3A, VCX3, VCX8R, VCXA
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 3 (VCX-A protein) (Variably charged protein X-A) (Variable charge protein on X with eight repeats) (VCX- 8r).

PRRT1_MOUSE
NC score	0.064991 (rank : 322)	θ value	θ > 10 (rank : 579)
Query Neighborhood Hits	376	Target Neighborhood Hits	102	Shared Neighborhood Hits	43
SwissProt Accessions	O35449	Gene names	Prrt1, Ng5
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 1.

ABI1_HUMAN
NC score	0.064941 (rank : 323)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	376	Target Neighborhood Hits	257	Shared Neighborhood Hits	49
SwissProt Accessions	Q8IZP0, O15147, O76049, O95060, Q5W070, Q5W072, Q8TB63, Q96S81, Q9NXZ9, Q9NYB8	Gene names	ABI1, SSH3BP1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Nap1-binding protein) (Nap1BP) (Abl-binding protein 4) (AblBP4).

DIAP1_HUMAN
NC score	0.064891 (rank : 324)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	376	Target Neighborhood Hits	784	Shared Neighborhood Hits	123
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

WASF3_HUMAN
NC score	0.064835 (rank : 325)	θ value	θ > 10 (rank : 681)
Query Neighborhood Hits	376	Target Neighborhood Hits	204	Shared Neighborhood Hits	76
SwissProt Accessions	Q9UPY6, O94974	Gene names	WASF3, KIAA0900, SCAR3, WAVE3
Domain Architecture
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3) (Verprolin homology domain-containing protein 3).

CIP4_HUMAN
NC score	0.064718 (rank : 326)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	376	Target Neighborhood Hits	374	Shared Neighborhood Hits	29
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

K0310_HUMAN
NC score	0.064600 (rank : 327)	θ value	θ > 10 (rank : 504)
Query Neighborhood Hits	376	Target Neighborhood Hits	420	Shared Neighborhood Hits	86
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

ITSN1_MOUSE
NC score	0.064512 (rank : 328)	θ value	5.27518 (rank : 305)
Query Neighborhood Hits	376	Target Neighborhood Hits	1669	Shared Neighborhood Hits	113
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

RIN3_MOUSE
NC score	0.064372 (rank : 329)	θ value	θ > 10 (rank : 590)
Query Neighborhood Hits	376	Target Neighborhood Hits	239	Shared Neighborhood Hits	83
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

ABI3_HUMAN
NC score	0.064255 (rank : 330)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	376	Target Neighborhood Hits	227	Shared Neighborhood Hits	53
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

SYNJ2_HUMAN
NC score	0.064172 (rank : 331)	θ value	θ > 10 (rank : 641)
Query Neighborhood Hits	376	Target Neighborhood Hits	136	Shared Neighborhood Hits	51
SwissProt Accessions	O15056, Q5TA13, Q5TA16, Q5TA19, Q86XK0, Q8IZA8, Q9H226	Gene names	SYNJ2, KIAA0348
Domain Architecture	No domain graphic available
Description	Synaptojanin-2 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 2).

CO039_MOUSE
NC score	0.064033 (rank : 332)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	376	Target Neighborhood Hits	445	Shared Neighborhood Hits	92
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

STAC_HUMAN
NC score	0.064013 (rank : 333)	θ value	θ > 10 (rank : 637)
Query Neighborhood Hits	376	Target Neighborhood Hits	276	Shared Neighborhood Hits	32
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

BNIP2_HUMAN
NC score	0.063853 (rank : 334)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	376	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q12982	Gene names	BNIP2, NIP2
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 2.

STAC3_MOUSE
NC score	0.063829 (rank : 335)	θ value	θ > 10 (rank : 636)
Query Neighborhood Hits	376	Target Neighborhood Hits	232	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

BNIP2_MOUSE
NC score	0.063741 (rank : 336)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	376	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	O54940	Gene names	Bnip2, Nip2l
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 2.

DNMBP_MOUSE
NC score	0.063596 (rank : 337)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	376	Target Neighborhood Hits	435	Shared Neighborhood Hits	63
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

PDC6I_HUMAN
NC score	0.063594 (rank : 338)	θ value	θ > 10 (rank : 554)
Query Neighborhood Hits	376	Target Neighborhood Hits	278	Shared Neighborhood Hits	93
SwissProt Accessions	Q8WUM4, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5	Gene names	PDCD6IP, AIP1, ALIX, KIAA1375
Domain Architecture
Description	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95).

ENL_HUMAN
NC score	0.063549 (rank : 339)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	376	Target Neighborhood Hits	305	Shared Neighborhood Hits	53
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

TB182_HUMAN
NC score	0.063481 (rank : 340)	θ value	θ > 10 (rank : 651)
Query Neighborhood Hits	376	Target Neighborhood Hits	414	Shared Neighborhood Hits	80
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

GAB1_HUMAN
NC score	0.063404 (rank : 341)	θ value	0.0148317 (rank : 94)
Query Neighborhood Hits	376	Target Neighborhood Hits	279	Shared Neighborhood Hits	46
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

MYO15_MOUSE
NC score	0.063312 (rank : 342)	θ value	θ > 10 (rank : 527)
Query Neighborhood Hits	376	Target Neighborhood Hits	467	Shared Neighborhood Hits	94
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

RIN3_HUMAN
NC score	0.063092 (rank : 343)	θ value	θ > 10 (rank : 589)
Query Neighborhood Hits	376	Target Neighborhood Hits	227	Shared Neighborhood Hits	79
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

MISS_MOUSE
NC score	0.063056 (rank : 344)	θ value	θ > 10 (rank : 516)
Query Neighborhood Hits	376	Target Neighborhood Hits	444	Shared Neighborhood Hits	81
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

SHAN1_HUMAN
NC score	0.062989 (rank : 345)	θ value	θ > 10 (rank : 618)
Query Neighborhood Hits	376	Target Neighborhood Hits	1041	Shared Neighborhood Hits	150
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

DNMBP_HUMAN
NC score	0.062790 (rank : 346)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	376	Target Neighborhood Hits	413	Shared Neighborhood Hits	51
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

VAV3_MOUSE
NC score	0.062604 (rank : 347)	θ value	θ > 10 (rank : 670)
Query Neighborhood Hits	376	Target Neighborhood Hits	404	Shared Neighborhood Hits	39
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

VAV3_HUMAN
NC score	0.062579 (rank : 348)	θ value	θ > 10 (rank : 669)
Query Neighborhood Hits	376	Target Neighborhood Hits	398	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

NEUM_HUMAN
NC score	0.062535 (rank : 349)	θ value	θ > 10 (rank : 539)
Query Neighborhood Hits	376	Target Neighborhood Hits	132	Shared Neighborhood Hits	35
SwissProt Accessions	P17677	Gene names	GAP43
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (PP46) (Neural phosphoprotein B-50).

SPR1B_MOUSE
NC score	0.062532 (rank : 350)	θ value	0.0148317 (rank : 96)
Query Neighborhood Hits	376	Target Neighborhood Hits	395	Shared Neighborhood Hits	57
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

RBM12_MOUSE
NC score	0.062482 (rank : 351)	θ value	θ > 10 (rank : 585)
Query Neighborhood Hits	376	Target Neighborhood Hits	313	Shared Neighborhood Hits	75
SwissProt Accessions	Q8R4X3, Q8K373, Q8R302, Q9CS80	Gene names	Rbm12
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

GRAP2_HUMAN
NC score	0.062358 (rank : 352)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	376	Target Neighborhood Hits	304	Shared Neighborhood Hits	38
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

IF4G1_MOUSE
NC score	0.061974 (rank : 353)	θ value	3.0926 (rank : 269)
Query Neighborhood Hits	376	Target Neighborhood Hits	534	Shared Neighborhood Hits	81
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

STAC3_HUMAN
NC score	0.061953 (rank : 354)	θ value	θ > 10 (rank : 635)
Query Neighborhood Hits	376	Target Neighborhood Hits	228	Shared Neighborhood Hits	28
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

EFS_MOUSE
NC score	0.061646 (rank : 355)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	376	Target Neighborhood Hits	389	Shared Neighborhood Hits	78
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

CS007_HUMAN
NC score	0.061361 (rank : 356)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	376	Target Neighborhood Hits	401	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

AP180_MOUSE
NC score	0.061268 (rank : 357)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	376	Target Neighborhood Hits	194	Shared Neighborhood Hits	54
SwissProt Accessions	Q61548, Q61547	Gene names	Snap91
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein) (Phosphoprotein F1- 20).

TGON2_HUMAN
NC score	0.061173 (rank : 358)	θ value	θ > 10 (rank : 657)
Query Neighborhood Hits	376	Target Neighborhood Hits	1037	Shared Neighborhood Hits	102
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

S23IP_MOUSE
NC score	0.061026 (rank : 359)	θ value	3.0926 (rank : 277)
Query Neighborhood Hits	376	Target Neighborhood Hits	363	Shared Neighborhood Hits	76
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

EPN1_HUMAN
NC score	0.060815 (rank : 360)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	376	Target Neighborhood Hits	206	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Y6I3, Q86ST3, Q9HA18	Gene names	EPN1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (EH domain-binding mitotic phosphoprotein).

ABI3_MOUSE
NC score	0.060740 (rank : 361)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	376	Target Neighborhood Hits	227	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

ATCAY_MOUSE
NC score	0.060719 (rank : 362)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	376	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BHE3, Q3TR94	Gene names	Atcay
Domain Architecture
Description	Caytaxin.

SC24D_HUMAN
NC score	0.060706 (rank : 363)	θ value	θ > 10 (rank : 600)
Query Neighborhood Hits	376	Target Neighborhood Hits	173	Shared Neighborhood Hits	61
SwissProt Accessions	O94855	Gene names	SEC24D, KIAA0755
Domain Architecture
Description	Protein transport protein Sec24D (SEC24-related protein D).

ATX2_HUMAN
NC score	0.060627 (rank : 364)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	376	Target Neighborhood Hits	375	Shared Neighborhood Hits	81
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

SPR1A_MOUSE
NC score	0.060552 (rank : 365)	θ value	0.21417 (rank : 139)
Query Neighborhood Hits	376	Target Neighborhood Hits	343	Shared Neighborhood Hits	50
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

SDC3_MOUSE
NC score	0.060528 (rank : 366)	θ value	θ > 10 (rank : 602)
Query Neighborhood Hits	376	Target Neighborhood Hits	107	Shared Neighborhood Hits	41
SwissProt Accessions	Q64519, Q3UDD9, Q6ZQA4, Q7TQD4	Gene names	Sdc3, Kiaa0468
Domain Architecture
Description	Syndecan-3 precursor (SYND3).

VASP_HUMAN
NC score	0.060487 (rank : 367)	θ value	θ > 10 (rank : 665)
Query Neighborhood Hits	376	Target Neighborhood Hits	201	Shared Neighborhood Hits	69
SwissProt Accessions	P50552, Q6PIZ1, Q93035	Gene names	VASP
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

WASF3_MOUSE
NC score	0.060476 (rank : 368)	θ value	θ > 10 (rank : 682)
Query Neighborhood Hits	376	Target Neighborhood Hits	188	Shared Neighborhood Hits	77
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

NCF2_HUMAN
NC score	0.060455 (rank : 369)	θ value	θ > 10 (rank : 531)
Query Neighborhood Hits	376	Target Neighborhood Hits	229	Shared Neighborhood Hits	27
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

ABI1_MOUSE
NC score	0.060417 (rank : 370)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	376	Target Neighborhood Hits	246	Shared Neighborhood Hits	38
SwissProt Accessions	Q8CBW3, Q60747, Q91ZM5, Q923I9, Q99KH4	Gene names	Abi1, Ssh3bp1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Ablphilin-1).

FMNL_MOUSE
NC score	0.060413 (rank : 371)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	376	Target Neighborhood Hits	428	Shared Neighborhood Hits	107
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

NEUM_MOUSE
NC score	0.060370 (rank : 372)	θ value	θ > 10 (rank : 540)
Query Neighborhood Hits	376	Target Neighborhood Hits	149	Shared Neighborhood Hits	32
SwissProt Accessions	P06837	Gene names	Gap43, Basp2
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (Calmodulin-binding protein P-57).

SYP2L_MOUSE
NC score	0.060338 (rank : 373)	θ value	θ > 10 (rank : 644)
Query Neighborhood Hits	376	Target Neighborhood Hits	289	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

ATX2_MOUSE
NC score	0.060320 (rank : 374)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	376	Target Neighborhood Hits	445	Shared Neighborhood Hits	88
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

AFF1_MOUSE
NC score	0.060254 (rank : 375)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	376	Target Neighborhood Hits	351	Shared Neighborhood Hits	81
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

ATCAY_HUMAN
NC score	0.060201 (rank : 376)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	376	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	Q86WG3, Q8NAQ2, Q8TAQ3, Q96HC6, Q96JF5	Gene names	ATCAY, KIAA1872
Domain Architecture
Description	Caytaxin (Ataxia Cayman type protein) (BNIP-H).

TM108_HUMAN
NC score	0.060109 (rank : 377)	θ value	θ > 10 (rank : 658)
Query Neighborhood Hits	376	Target Neighborhood Hits	166	Shared Neighborhood Hits	52
SwissProt Accessions	Q6UXF1, Q9BQH1, Q9BW81, Q9C0H3	Gene names	TMEM108, KIAA1690
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

MILK2_HUMAN
NC score	0.059972 (rank : 378)	θ value	8.99809 (rank : 366)
Query Neighborhood Hits	376	Target Neighborhood Hits	457	Shared Neighborhood Hits	93
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

AP180_HUMAN
NC score	0.059951 (rank : 379)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	376	Target Neighborhood Hits	183	Shared Neighborhood Hits	56
SwissProt Accessions	O60641, Q5JX13, Q68DL9, Q6P9D3, Q9NTY7	Gene names	SNAP91, KIAA0656
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein).

BNIPL_HUMAN
NC score	0.059882 (rank : 380)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	376	Target Neighborhood Hits	40	Shared Neighborhood Hits	7
SwissProt Accessions	Q7Z465, Q6DK43, Q8TCY7, Q8WYG2	Gene names	BNIPL
Domain Architecture	No domain graphic available
Description	Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein.

ENAH_HUMAN
NC score	0.059840 (rank : 381)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	376	Target Neighborhood Hits	784	Shared Neighborhood Hits	118
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

PRRT1_HUMAN
NC score	0.059788 (rank : 382)	θ value	θ > 10 (rank : 578)
Query Neighborhood Hits	376	Target Neighborhood Hits	94	Shared Neighborhood Hits	37
SwissProt Accessions	Q99946, Q96DW3, Q96NQ8	Gene names	PRRT1, C6orf31, NG5
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 1.

PKHA4_HUMAN
NC score	0.059657 (rank : 383)	θ value	θ > 10 (rank : 561)
Query Neighborhood Hits	376	Target Neighborhood Hits	283	Shared Neighborhood Hits	67
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

SNPC4_HUMAN
NC score	0.059600 (rank : 384)	θ value	4.03905 (rank : 298)
Query Neighborhood Hits	376	Target Neighborhood Hits	589	Shared Neighborhood Hits	97
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

CENG1_MOUSE
NC score	0.059538 (rank : 385)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	376	Target Neighborhood Hits	531	Shared Neighborhood Hits	66
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

ZN598_HUMAN
NC score	0.059486 (rank : 386)	θ value	θ > 10 (rank : 698)
Query Neighborhood Hits	376	Target Neighborhood Hits	339	Shared Neighborhood Hits	66
SwissProt Accessions	Q86UK7, Q8IW49, Q8N3D9, Q96FG3, Q9H7J3	Gene names	ZNF598
Domain Architecture	No domain graphic available
Description	Zinc finger protein 598.

IRS2_HUMAN
NC score	0.059484 (rank : 387)	θ value	θ > 10 (rank : 501)
Query Neighborhood Hits	376	Target Neighborhood Hits	262	Shared Neighborhood Hits	83
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

GRAP2_MOUSE
NC score	0.059426 (rank : 388)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	376	Target Neighborhood Hits	297	Shared Neighborhood Hits	36
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

BCAR1_HUMAN
NC score	0.059300 (rank : 389)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	376	Target Neighborhood Hits	554	Shared Neighborhood Hits	80
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

CSKI2_MOUSE
NC score	0.059269 (rank : 390)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	376	Target Neighborhood Hits	812	Shared Neighborhood Hits	121
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

PSL1_HUMAN
NC score	0.059252 (rank : 391)	θ value	0.0330416 (rank : 111)
Query Neighborhood Hits	376	Target Neighborhood Hits	650	Shared Neighborhood Hits	74
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

VCXC_HUMAN
NC score	0.059083 (rank : 392)	θ value	θ > 10 (rank : 674)
Query Neighborhood Hits	376	Target Neighborhood Hits	139	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H321	Gene names	VCXC
Domain Architecture	No domain graphic available
Description	VCX-C protein (Variably charged protein X-C).

PS1C2_MOUSE
NC score	0.059047 (rank : 393)	θ value	θ > 10 (rank : 581)
Query Neighborhood Hits	376	Target Neighborhood Hits	59	Shared Neighborhood Hits	22
SwissProt Accessions	Q80ZC9	Gene names	Psors1c2, Spr1
Domain Architecture	No domain graphic available
Description	Psoriasis susceptibility 1 candidate gene 2 protein homolog precursor (SPR1 protein).

BNIPL_MOUSE
NC score	0.058965 (rank : 394)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	376	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q99JU7, Q923E3	Gene names	Bnipl
Domain Architecture	No domain graphic available
Description	Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein.

P55G_HUMAN
NC score	0.058928 (rank : 395)	θ value	θ > 10 (rank : 547)
Query Neighborhood Hits	376	Target Neighborhood Hits	451	Shared Neighborhood Hits	25
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

CIZ1_HUMAN
NC score	0.058881 (rank : 396)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	376	Target Neighborhood Hits	359	Shared Neighborhood Hits	58
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

3BP2_MOUSE
NC score	0.058802 (rank : 397)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	376	Target Neighborhood Hits	142	Shared Neighborhood Hits	33
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

TARA_MOUSE
NC score	0.058776 (rank : 398)	θ value	θ > 10 (rank : 649)
Query Neighborhood Hits	376	Target Neighborhood Hits	1133	Shared Neighborhood Hits	117
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

VCX1_HUMAN
NC score	0.058739 (rank : 399)	θ value	θ > 10 (rank : 672)
Query Neighborhood Hits	376	Target Neighborhood Hits	129	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H320, Q9P0H3	Gene names	VCX, VCX1, VCX10R, VCXB1
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 1 (VCX-B1 protein) (Variably charged protein X-B1) (Variable charge protein on X with ten repeats) (VCX- 10r).

DIAP1_MOUSE
NC score	0.058707 (rank : 400)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	376	Target Neighborhood Hits	839	Shared Neighborhood Hits	108
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

IL3RB_HUMAN
NC score	0.058572 (rank : 401)	θ value	θ > 10 (rank : 499)
Query Neighborhood Hits	376	Target Neighborhood Hits	163	Shared Neighborhood Hits	40
SwissProt Accessions	P32927	Gene names	CSF2RB, IL3RB, IL5RB
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen) (CDw131).

CASC3_MOUSE
NC score	0.058409 (rank : 402)	θ value	0.47712 (rank : 167)
Query Neighborhood Hits	376	Target Neighborhood Hits	333	Shared Neighborhood Hits	57
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

EPN1_MOUSE
NC score	0.058338 (rank : 403)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	376	Target Neighborhood Hits	240	Shared Neighborhood Hits	70
SwissProt Accessions	Q80VP1, O70446	Gene names	Epn1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (Intersectin-EH-binding protein 1) (Ibp1).

P55G_MOUSE
NC score	0.058162 (rank : 404)	θ value	θ > 10 (rank : 548)
Query Neighborhood Hits	376	Target Neighborhood Hits	401	Shared Neighborhood Hits	24
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

VAV2_MOUSE
NC score	0.058095 (rank : 405)	θ value	θ > 10 (rank : 668)
Query Neighborhood Hits	376	Target Neighborhood Hits	456	Shared Neighborhood Hits	40
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

AUTS2_HUMAN
NC score	0.058039 (rank : 406)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	376	Target Neighborhood Hits	342	Shared Neighborhood Hits	84
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

MYO1F_HUMAN
NC score	0.057890 (rank : 407)	θ value	θ > 10 (rank : 529)
Query Neighborhood Hits	376	Target Neighborhood Hits	275	Shared Neighborhood Hits	40
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

LDB3_HUMAN
NC score	0.057752 (rank : 408)	θ value	θ > 10 (rank : 507)
Query Neighborhood Hits	376	Target Neighborhood Hits	497	Shared Neighborhood Hits	109
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

PDCD7_HUMAN
NC score	0.057735 (rank : 409)	θ value	θ > 10 (rank : 556)
Query Neighborhood Hits	376	Target Neighborhood Hits	255	Shared Neighborhood Hits	62
SwissProt Accessions	Q8N8D1, Q96AK8, Q9Y6D7	Gene names	PDCD7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18) (HES18).

TP53B_MOUSE
NC score	0.057696 (rank : 410)	θ value	θ > 10 (rank : 661)
Query Neighborhood Hits	376	Target Neighborhood Hits	644	Shared Neighborhood Hits	87
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

PAF49_HUMAN
NC score	0.057580 (rank : 411)	θ value	θ > 10 (rank : 549)
Query Neighborhood Hits	376	Target Neighborhood Hits	169	Shared Neighborhood Hits	33
SwissProt Accessions	O15446, Q32N11, Q7Z5U2, Q9UPF6	Gene names	CD3EAP, ASE1, CAST, PAF49
Domain Architecture	No domain graphic available
Description	RNA polymerase I-associated factor PAF49 (Anti-sense to ERCC-1 protein) (ASE-1) (CD3-epsilon-associated protein) (CD3E-associated protein) (CAST).

VAV2_HUMAN
NC score	0.057389 (rank : 412)	θ value	θ > 10 (rank : 667)
Query Neighborhood Hits	376	Target Neighborhood Hits	453	Shared Neighborhood Hits	40
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

SRC8_MOUSE
NC score	0.057366 (rank : 413)	θ value	θ > 10 (rank : 632)
Query Neighborhood Hits	376	Target Neighborhood Hits	292	Shared Neighborhood Hits	37
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

VASP_MOUSE
NC score	0.057317 (rank : 414)	θ value	θ > 10 (rank : 666)
Query Neighborhood Hits	376	Target Neighborhood Hits	195	Shared Neighborhood Hits	63
SwissProt Accessions	P70460, Q3TAP0, Q3TCD2, Q3U0C2, Q3UDF1, Q91VD2, Q9R214	Gene names	Vasp
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

NCK1_HUMAN
NC score	0.057061 (rank : 415)	θ value	θ > 10 (rank : 534)
Query Neighborhood Hits	376	Target Neighborhood Hits	312	Shared Neighborhood Hits	35
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

PDC6I_MOUSE
NC score	0.056998 (rank : 416)	θ value	θ > 10 (rank : 555)
Query Neighborhood Hits	376	Target Neighborhood Hits	275	Shared Neighborhood Hits	91
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

ITSN2_HUMAN
NC score	0.056968 (rank : 417)	θ value	θ > 10 (rank : 502)
Query Neighborhood Hits	376	Target Neighborhood Hits	1173	Shared Neighborhood Hits	70
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

MKL1_MOUSE
NC score	0.056681 (rank : 418)	θ value	1.06291 (rank : 210)
Query Neighborhood Hits	376	Target Neighborhood Hits	667	Shared Neighborhood Hits	90
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

DAPP1_MOUSE
NC score	0.056679 (rank : 419)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	376	Target Neighborhood Hits	225	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

INP5E_HUMAN
NC score	0.056640 (rank : 420)	θ value	θ > 10 (rank : 500)
Query Neighborhood Hits	376	Target Neighborhood Hits	201	Shared Neighborhood Hits	39
SwissProt Accessions	Q9NRR6, Q15734	Gene names	INPP5E
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

NCOR2_MOUSE
NC score	0.056621 (rank : 421)	θ value	θ > 10 (rank : 536)
Query Neighborhood Hits	376	Target Neighborhood Hits	790	Shared Neighborhood Hits	116
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

LAD1_HUMAN
NC score	0.056567 (rank : 422)	θ value	θ > 10 (rank : 506)
Query Neighborhood Hits	376	Target Neighborhood Hits	441	Shared Neighborhood Hits	60
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

PKHA6_MOUSE
NC score	0.056475 (rank : 423)	θ value	θ > 10 (rank : 562)
Query Neighborhood Hits	376	Target Neighborhood Hits	591	Shared Neighborhood Hits	63
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

HEMGN_MOUSE
NC score	0.056364 (rank : 424)	θ value	0.0330416 (rank : 108)
Query Neighborhood Hits	376	Target Neighborhood Hits	81	Shared Neighborhood Hits	16
SwissProt Accessions	Q9ERZ0, Q3TAE6, Q80YT2, Q8CF29	Gene names	Hemgn, Ndr
Domain Architecture	No domain graphic available
Description	Hemogen (Hemopoietic gene protein) (Negative differentiation regulator protein) (mNDR).

CRKL_HUMAN
NC score	0.056271 (rank : 425)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	376	Target Neighborhood Hits	313	Shared Neighborhood Hits	37
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

CEND_HUMAN
NC score	0.056263 (rank : 426)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	376	Target Neighborhood Hits	84	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N111, Q9NYM6	Gene names	CEND1, BM88
Domain Architecture	No domain graphic available
Description	Cell cycle exit and neuronal differentiation protein 1 (BM88 antigen).

MYO10_HUMAN
NC score	0.056228 (rank : 427)	θ value	θ > 10 (rank : 525)
Query Neighborhood Hits	376	Target Neighborhood Hits	920	Shared Neighborhood Hits	60
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

RTN4_HUMAN
NC score	0.056195 (rank : 428)	θ value	θ > 10 (rank : 593)
Query Neighborhood Hits	376	Target Neighborhood Hits	357	Shared Neighborhood Hits	91
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

CENG1_HUMAN
NC score	0.056157 (rank : 429)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	376	Target Neighborhood Hits	544	Shared Neighborhood Hits	69
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

MYO1F_MOUSE
NC score	0.055854 (rank : 430)	θ value	θ > 10 (rank : 530)
Query Neighborhood Hits	376	Target Neighborhood Hits	262	Shared Neighborhood Hits	26
SwissProt Accessions	P70248	Gene names	Myo1f
Domain Architecture
Description	Myosin If.

PTN23_HUMAN
NC score	0.055789 (rank : 431)	θ value	θ > 10 (rank : 582)
Query Neighborhood Hits	376	Target Neighborhood Hits	646	Shared Neighborhood Hits	136
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

IL3RB_MOUSE
NC score	0.055732 (rank : 432)	θ value	0.47712 (rank : 169)
Query Neighborhood Hits	376	Target Neighborhood Hits	355	Shared Neighborhood Hits	46
SwissProt Accessions	P26955	Gene names	Csf2rb, Aic2b, Csf2rb1, Il3rb1
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen).

TACC2_HUMAN
NC score	0.055658 (rank : 433)	θ value	0.365318 (rank : 165)
Query Neighborhood Hits	376	Target Neighborhood Hits	856	Shared Neighborhood Hits	103
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

TACC2_MOUSE
NC score	0.055600 (rank : 434)	θ value	θ > 10 (rank : 646)
Query Neighborhood Hits	376	Target Neighborhood Hits	774	Shared Neighborhood Hits	90
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

UN13A_HUMAN
NC score	0.055488 (rank : 435)	θ value	θ > 10 (rank : 663)
Query Neighborhood Hits	376	Target Neighborhood Hits	285	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

DAPP1_HUMAN
NC score	0.055441 (rank : 436)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	376	Target Neighborhood Hits	227	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DIDO1_HUMAN
NC score	0.055353 (rank : 437)	θ value	1.38821 (rank : 216)
Query Neighborhood Hits	376	Target Neighborhood Hits	960	Shared Neighborhood Hits	109
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

MN1_HUMAN
NC score	0.055316 (rank : 438)	θ value	θ > 10 (rank : 518)
Query Neighborhood Hits	376	Target Neighborhood Hits	196	Shared Neighborhood Hits	52
SwissProt Accessions	Q10571	Gene names	MN1
Domain Architecture	No domain graphic available
Description	Probable tumor suppressor protein MN1.

AL2S4_MOUSE
NC score	0.055232 (rank : 439)	θ value	0.813845 (rank : 189)
Query Neighborhood Hits	376	Target Neighborhood Hits	193	Shared Neighborhood Hits	32
SwissProt Accessions	Q3V0J1, Q3TIS2	Gene names	Als2cr4
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein homolog.

SC24A_MOUSE
NC score	0.055111 (rank : 440)	θ value	θ > 10 (rank : 599)
Query Neighborhood Hits	376	Target Neighborhood Hits	394	Shared Neighborhood Hits	71
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

SMRC2_MOUSE
NC score	0.055078 (rank : 441)	θ value	θ > 10 (rank : 626)
Query Neighborhood Hits	376	Target Neighborhood Hits	487	Shared Neighborhood Hits	84
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

SPR2H_MOUSE
NC score	0.055052 (rank : 442)	θ value	θ > 10 (rank : 628)
Query Neighborhood Hits	376	Target Neighborhood Hits	82	Shared Neighborhood Hits	27
SwissProt Accessions	O70559	Gene names	Sprr2h
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2H.

ITSN2_MOUSE
NC score	0.055035 (rank : 443)	θ value	θ > 10 (rank : 503)
Query Neighborhood Hits	376	Target Neighborhood Hits	1371	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

PYGO2_HUMAN
NC score	0.054952 (rank : 444)	θ value	θ > 10 (rank : 584)
Query Neighborhood Hits	376	Target Neighborhood Hits	189	Shared Neighborhood Hits	58
SwissProt Accessions	Q9BRQ0, Q8WYZ4, Q96CY2	Gene names	PYGO2
Domain Architecture
Description	Pygopus homolog 2.

NFH_HUMAN
NC score	0.054937 (rank : 445)	θ value	θ > 10 (rank : 541)
Query Neighborhood Hits	376	Target Neighborhood Hits	1242	Shared Neighborhood Hits	124
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

TACC3_HUMAN
NC score	0.054927 (rank : 446)	θ value	2.36792 (rank : 259)
Query Neighborhood Hits	376	Target Neighborhood Hits	779	Shared Neighborhood Hits	84
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

FA47A_HUMAN
NC score	0.054818 (rank : 447)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	376	Target Neighborhood Hits	451	Shared Neighborhood Hits	73
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

RD23B_MOUSE
NC score	0.054771 (rank : 448)	θ value	θ > 10 (rank : 586)
Query Neighborhood Hits	376	Target Neighborhood Hits	189	Shared Neighborhood Hits	61
SwissProt Accessions	P54728	Gene names	Rad23b, Mhr23b
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (mHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

MYO1E_HUMAN
NC score	0.054611 (rank : 449)	θ value	θ > 10 (rank : 528)
Query Neighborhood Hits	376	Target Neighborhood Hits	293	Shared Neighborhood Hits	34
SwissProt Accessions	Q12965, Q14778	Gene names	MYO1E, MYO1C
Domain Architecture
Description	Myosin Ie (Myosin Ic).

IF35_HUMAN
NC score	0.054411 (rank : 450)	θ value	θ > 10 (rank : 497)
Query Neighborhood Hits	376	Target Neighborhood Hits	130	Shared Neighborhood Hits	56
SwissProt Accessions	O00303, Q8N978	Gene names	EIF3S5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

SMR3B_HUMAN
NC score	0.054405 (rank : 451)	θ value	θ > 10 (rank : 624)
Query Neighborhood Hits	376	Target Neighborhood Hits	46	Shared Neighborhood Hits	21
SwissProt Accessions	P02814, Q9UBN0, Q9UCT0	Gene names	SMR3B, PBII, PROL3
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog B precursor (Proline-rich protein 3) (Proline-rich peptide P-B) [Contains: Peptide P-A; Peptide D1A].

PPRB_MOUSE
NC score	0.054290 (rank : 452)	θ value	θ > 10 (rank : 565)
Query Neighborhood Hits	376	Target Neighborhood Hits	354	Shared Neighborhood Hits	64
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

SMRC2_HUMAN
NC score	0.054158 (rank : 453)	θ value	θ > 10 (rank : 625)
Query Neighborhood Hits	376	Target Neighborhood Hits	499	Shared Neighborhood Hits	87
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

AB1IP_MOUSE
NC score	0.054143 (rank : 454)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	376	Target Neighborhood Hits	181	Shared Neighborhood Hits	68
SwissProt Accessions	Q8R5A3, O35329, Q8BRU0, Q99KV8	Gene names	Apbb1ip, Prel1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 48).

ARHG7_MOUSE
NC score	0.054095 (rank : 455)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	376	Target Neighborhood Hits	396	Shared Neighborhood Hits	35
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

OGFR_MOUSE
NC score	0.053937 (rank : 456)	θ value	θ > 10 (rank : 544)
Query Neighborhood Hits	376	Target Neighborhood Hits	584	Shared Neighborhood Hits	62
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

TROAP_HUMAN
NC score	0.053915 (rank : 457)	θ value	θ > 10 (rank : 662)
Query Neighborhood Hits	376	Target Neighborhood Hits	258	Shared Neighborhood Hits	60
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

SDC3_HUMAN
NC score	0.053879 (rank : 458)	θ value	θ > 10 (rank : 601)
Query Neighborhood Hits	376	Target Neighborhood Hits	103	Shared Neighborhood Hits	40
SwissProt Accessions	O75056, Q5T1Z6, Q5T1Z7, Q96CT3, Q96PR8	Gene names	SDC3, KIAA0468
Domain Architecture
Description	Syndecan-3 (SYND3).

JADE2_MOUSE
NC score	0.053851 (rank : 459)	θ value	0.0330416 (rank : 109)
Query Neighborhood Hits	376	Target Neighborhood Hits	560	Shared Neighborhood Hits	87
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

LPP_HUMAN
NC score	0.053660 (rank : 460)	θ value	0.0736092 (rank : 115)
Query Neighborhood Hits	376	Target Neighborhood Hits	775	Shared Neighborhood Hits	95
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

PTN23_MOUSE
NC score	0.053368 (rank : 461)	θ value	θ > 10 (rank : 583)
Query Neighborhood Hits	376	Target Neighborhood Hits	726	Shared Neighborhood Hits	151
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

GNAS1_MOUSE
NC score	0.053349 (rank : 462)	θ value	0.813845 (rank : 193)
Query Neighborhood Hits	376	Target Neighborhood Hits	651	Shared Neighborhood Hits	101
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

IL3B2_MOUSE
NC score	0.053321 (rank : 463)	θ value	0.365318 (rank : 162)
Query Neighborhood Hits	376	Target Neighborhood Hits	372	Shared Neighborhood Hits	48
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

CG1_HUMAN
NC score	0.053209 (rank : 464)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	376	Target Neighborhood Hits	222	Shared Neighborhood Hits	53
SwissProt Accessions	Q13495	Gene names	CXorf6, CG1
Domain Architecture	No domain graphic available
Description	CG1 protein (F18).

RU1C_MOUSE
NC score	0.053164 (rank : 465)	θ value	θ > 10 (rank : 596)
Query Neighborhood Hits	376	Target Neighborhood Hits	83	Shared Neighborhood Hits	30
SwissProt Accessions	Q62241	Gene names	Snrp1c, Snrpc
Domain Architecture
Description	U1 small nuclear ribonucleoprotein C (U1 snRNP protein C) (U1C protein) (U1-C).

PHLB1_HUMAN
NC score	0.053107 (rank : 466)	θ value	2.36792 (rank : 255)
Query Neighborhood Hits	376	Target Neighborhood Hits	1038	Shared Neighborhood Hits	122
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PPIP1_HUMAN
NC score	0.053094 (rank : 467)	θ value	θ > 10 (rank : 564)
Query Neighborhood Hits	376	Target Neighborhood Hits	389	Shared Neighborhood Hits	38
SwissProt Accessions	O43586, O43585, O95657	Gene names	PSTPIP1, CD2BP1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP).

APXL_HUMAN
NC score	0.053076 (rank : 468)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	376	Target Neighborhood Hits	553	Shared Neighborhood Hits	77
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

RUSC1_HUMAN
NC score	0.053043 (rank : 469)	θ value	θ > 10 (rank : 597)
Query Neighborhood Hits	376	Target Neighborhood Hits	226	Shared Neighborhood Hits	43
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

ACINU_MOUSE
NC score	0.053001 (rank : 470)	θ value	8.99809 (rank : 352)
Query Neighborhood Hits	376	Target Neighborhood Hits	712	Shared Neighborhood Hits	86
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

SPRR3_MOUSE
NC score	0.052984 (rank : 471)	θ value	θ > 10 (rank : 629)
Query Neighborhood Hits	376	Target Neighborhood Hits	106	Shared Neighborhood Hits	31
SwissProt Accessions	O09116	Gene names	Sprr3
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta).

SRC8_HUMAN
NC score	0.052868 (rank : 472)	θ value	θ > 10 (rank : 631)
Query Neighborhood Hits	376	Target Neighborhood Hits	269	Shared Neighborhood Hits	32
SwissProt Accessions	Q14247	Gene names	CTTN, EMS1
Domain Architecture
Description	Src substrate cortactin (Amplaxin) (Oncogene EMS1).

PKHA1_HUMAN
NC score	0.052823 (rank : 473)	θ value	θ > 10 (rank : 560)
Query Neighborhood Hits	376	Target Neighborhood Hits	127	Shared Neighborhood Hits	16
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

AMPH_HUMAN
NC score	0.052797 (rank : 474)	θ value	2.36792 (rank : 241)
Query Neighborhood Hits	376	Target Neighborhood Hits	455	Shared Neighborhood Hits	70
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

MAVS_HUMAN
NC score	0.052779 (rank : 475)	θ value	θ > 10 (rank : 512)
Query Neighborhood Hits	376	Target Neighborhood Hits	271	Shared Neighborhood Hits	59
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

ANR11_HUMAN
NC score	0.052774 (rank : 476)	θ value	0.0252991 (rank : 103)
Query Neighborhood Hits	376	Target Neighborhood Hits	1289	Shared Neighborhood Hits	110
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

EVL_HUMAN
NC score	0.052699 (rank : 477)	θ value	0.279714 (rank : 144)
Query Neighborhood Hits	376	Target Neighborhood Hits	260	Shared Neighborhood Hits	69
SwissProt Accessions	Q9UI08, O95884, Q7Z522, Q8TBV1, Q9UF25, Q9UIC2	Gene names	EVL, RNB6
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

SYNJ2_MOUSE
NC score	0.052680 (rank : 478)	θ value	θ > 10 (rank : 642)
Query Neighborhood Hits	376	Target Neighborhood Hits	87	Shared Neighborhood Hits	28
SwissProt Accessions	Q9D2G5, O35404, O88399, O88400, O88401, O88402, O88403, O88404	Gene names	Synj2, Kiaa0348
Domain Architecture
Description	Synaptojanin-2 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 2).

CT151_HUMAN
NC score	0.052515 (rank : 479)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	376	Target Neighborhood Hits	382	Shared Neighborhood Hits	69
SwissProt Accessions	Q8NC74, Q8N4Z9, Q9BR75, Q9H0Y9	Gene names	C20orf151
Domain Architecture
Description	Uncharacterized protein C20orf151.

SEPT9_HUMAN
NC score	0.052439 (rank : 480)	θ value	0.21417 (rank : 138)
Query Neighborhood Hits	376	Target Neighborhood Hits	706	Shared Neighborhood Hits	89
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

PRCC_HUMAN
NC score	0.052294 (rank : 481)	θ value	θ > 10 (rank : 568)
Query Neighborhood Hits	376	Target Neighborhood Hits	109	Shared Neighborhood Hits	38
SwissProt Accessions	Q92733, O00665, O00724	Gene names	PRCC, TPRC
Domain Architecture	No domain graphic available
Description	Proline-rich protein PRCC (Papillary renal cell carcinoma translocation-associated gene protein).

CEL_HUMAN
NC score	0.052255 (rank : 482)	θ value	0.0113563 (rank : 90)
Query Neighborhood Hits	376	Target Neighborhood Hits	896	Shared Neighborhood Hits	102
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

ZN385_HUMAN
NC score	0.052172 (rank : 483)	θ value	0.813845 (rank : 198)
Query Neighborhood Hits	376	Target Neighborhood Hits	614	Shared Neighborhood Hits	65
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

OSTF1_HUMAN
NC score	0.052087 (rank : 484)	θ value	θ > 10 (rank : 545)
Query Neighborhood Hits	376	Target Neighborhood Hits	466	Shared Neighborhood Hits	31
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

BAZ2A_MOUSE
NC score	0.052014 (rank : 485)	θ value	1.81305 (rank : 227)
Query Neighborhood Hits	376	Target Neighborhood Hits	744	Shared Neighborhood Hits	102
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

TENS1_HUMAN
NC score	0.051970 (rank : 486)	θ value	θ > 10 (rank : 656)
Query Neighborhood Hits	376	Target Neighborhood Hits	400	Shared Neighborhood Hits	70
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

LDB3_MOUSE
NC score	0.051935 (rank : 487)	θ value	5.27518 (rank : 306)
Query Neighborhood Hits	376	Target Neighborhood Hits	510	Shared Neighborhood Hits	111
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

CJ108_HUMAN
NC score	0.051799 (rank : 488)	θ value	0.365318 (rank : 157)
Query Neighborhood Hits	376	Target Neighborhood Hits	165	Shared Neighborhood Hits	24
SwissProt Accessions	Q8N8Z3	Gene names	C10orf108
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C10orf108.

ZYX_MOUSE
NC score	0.051797 (rank : 489)	θ value	θ > 10 (rank : 700)
Query Neighborhood Hits	376	Target Neighborhood Hits	347	Shared Neighborhood Hits	81
SwissProt Accessions	Q62523, P70461	Gene names	Zyx
Domain Architecture
Description	Zyxin.

CRKL_MOUSE
NC score	0.051708 (rank : 490)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	376	Target Neighborhood Hits	307	Shared Neighborhood Hits	35
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

ASPP2_HUMAN
NC score	0.051691 (rank : 491)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	376	Target Neighborhood Hits	1156	Shared Neighborhood Hits	98
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

DDFL1_HUMAN
NC score	0.051604 (rank : 492)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	376	Target Neighborhood Hits	353	Shared Neighborhood Hits	31
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

ZYX_HUMAN
NC score	0.051580 (rank : 493)	θ value	θ > 10 (rank : 699)
Query Neighborhood Hits	376	Target Neighborhood Hits	387	Shared Neighborhood Hits	91
SwissProt Accessions	Q15942	Gene names	ZYX
Domain Architecture
Description	Zyxin (Zyxin-2).

SF3B1_HUMAN
NC score	0.051568 (rank : 494)	θ value	1.81305 (rank : 237)
Query Neighborhood Hits	376	Target Neighborhood Hits	341	Shared Neighborhood Hits	48
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

RUSC2_HUMAN
NC score	0.051545 (rank : 495)	θ value	θ > 10 (rank : 598)
Query Neighborhood Hits	376	Target Neighborhood Hits	205	Shared Neighborhood Hits	50
SwissProt Accessions	Q8N2Y8, O15080, Q6P1W7	Gene names	RUSC2, KIAA0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

RU1C_HUMAN
NC score	0.051491 (rank : 496)	θ value	θ > 10 (rank : 595)
Query Neighborhood Hits	376	Target Neighborhood Hits	81	Shared Neighborhood Hits	29
SwissProt Accessions	P09234	Gene names	SNRPC
Domain Architecture
Description	U1 small nuclear ribonucleoprotein C (U1 snRNP protein C) (U1C protein) (U1-C).

CITE4_HUMAN
NC score	0.051459 (rank : 497)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	376	Target Neighborhood Hits	67	Shared Neighborhood Hits	29
SwissProt Accessions	Q96RK1	Gene names	CITED4, MRG2
Domain Architecture	No domain graphic available
Description	Cbp/p300-interacting transactivator 4 (MSG1-related protein 2) (MRG- 2).

RAI1_MOUSE
NC score	0.051382 (rank : 498)	θ value	0.813845 (rank : 197)
Query Neighborhood Hits	376	Target Neighborhood Hits	344	Shared Neighborhood Hits	57
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

MAP1B_HUMAN
NC score	0.051366 (rank : 499)	θ value	θ > 10 (rank : 509)
Query Neighborhood Hits	376	Target Neighborhood Hits	903	Shared Neighborhood Hits	86
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

TS13_MOUSE
NC score	0.051363 (rank : 500)	θ value	0.62314 (rank : 186)
Query Neighborhood Hits	376	Target Neighborhood Hits	191	Shared Neighborhood Hits	20
SwissProt Accessions	Q01755	Gene names	Tcp11
Domain Architecture
Description	Testis-specific protein PBS13.

CD248_HUMAN
NC score	0.051138 (rank : 501)	θ value	0.00134147 (rank : 79)
Query Neighborhood Hits	376	Target Neighborhood Hits	679	Shared Neighborhood Hits	76
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

UN13B_HUMAN
NC score	0.050942 (rank : 502)	θ value	θ > 10 (rank : 664)
Query Neighborhood Hits	376	Target Neighborhood Hits	217	Shared Neighborhood Hits	21
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

VAV_MOUSE
NC score	0.050894 (rank : 503)	θ value	θ > 10 (rank : 671)
Query Neighborhood Hits	376	Target Neighborhood Hits	430	Shared Neighborhood Hits	36
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

RTN4_MOUSE
NC score	0.050863 (rank : 504)	θ value	θ > 10 (rank : 594)
Query Neighborhood Hits	376	Target Neighborhood Hits	341	Shared Neighborhood Hits	86
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

NRX2B_HUMAN
NC score	0.050854 (rank : 505)	θ value	0.279714 (rank : 148)
Query Neighborhood Hits	376	Target Neighborhood Hits	481	Shared Neighborhood Hits	55
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

CCD1A_HUMAN
NC score	0.050614 (rank : 506)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	376	Target Neighborhood Hits	123	Shared Neighborhood Hits	40
SwissProt Accessions	Q6P1N0, Q7Z435, Q86XV0, Q8NF89, Q9H603, Q9NXI1	Gene names	CC2D1A
Domain Architecture	No domain graphic available
Description	Coiled-coil and C2 domain-containing protein 1A (Five repressor element under dual repression-binding protein 1) (FRE under dual repression-binding protein 1) (Freud-1) (Putative NF-kappa-B- activating protein 023N).

ARHGF_HUMAN
NC score	0.050582 (rank : 507)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	376	Target Neighborhood Hits	214	Shared Neighborhood Hits	71
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

GAB1_MOUSE
NC score	0.050536 (rank : 508)	θ value	1.06291 (rank : 205)
Query Neighborhood Hits	376	Target Neighborhood Hits	233	Shared Neighborhood Hits	32
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

SF3B1_MOUSE
NC score	0.050490 (rank : 509)	θ value	1.81305 (rank : 238)
Query Neighborhood Hits	376	Target Neighborhood Hits	352	Shared Neighborhood Hits	48
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

CRTC1_MOUSE
NC score	0.050220 (rank : 510)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	376	Target Neighborhood Hits	230	Shared Neighborhood Hits	59
SwissProt Accessions	Q68ED7, Q6ZQ85	Gene names	Crtc1, Kiaa0616, Mect1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1 homolog).

OSTF1_MOUSE
NC score	0.050044 (rank : 511)	θ value	θ > 10 (rank : 546)
Query Neighborhood Hits	376	Target Neighborhood Hits	467	Shared Neighborhood Hits	31
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

SPRR3_HUMAN
NC score	0.049813 (rank : 512)	θ value	8.99809 (rank : 373)
Query Neighborhood Hits	376	Target Neighborhood Hits	102	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UBC9, O75597, Q4ZGI7, Q5T525, Q8NET7, Q9UDG3	Gene names	SPRR3, SPRC
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta) (Esophagin) (22 kDa pancornulin).

ARMX2_MOUSE
NC score	0.049515 (rank : 513)	θ value	0.813845 (rank : 190)
Query Neighborhood Hits	376	Target Neighborhood Hits	349	Shared Neighborhood Hits	58
SwissProt Accessions	Q6A058, Q9CXI9	Gene names	Armcx2, Kiaa0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2.

BRD8_MOUSE
NC score	0.049465 (rank : 514)	θ value	0.365318 (rank : 155)
Query Neighborhood Hits	376	Target Neighborhood Hits	422	Shared Neighborhood Hits	55
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

NSD1_MOUSE
NC score	0.049030 (rank : 515)	θ value	1.81305 (rank : 234)
Query Neighborhood Hits	376	Target Neighborhood Hits	472	Shared Neighborhood Hits	66
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

CECR2_HUMAN
NC score	0.048679 (rank : 516)	θ value	0.365318 (rank : 156)
Query Neighborhood Hits	376	Target Neighborhood Hits	543	Shared Neighborhood Hits	70
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

CP007_MOUSE
NC score	0.047173 (rank : 517)	θ value	0.21417 (rank : 134)
Query Neighborhood Hits	376	Target Neighborhood Hits	231	Shared Neighborhood Hits	25
SwissProt Accessions	Q8C190, Q6PFD1	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf7 homolog (5-day ovary-specific transcript 1 protein).

SSBP4_HUMAN
NC score	0.047123 (rank : 518)	θ value	0.279714 (rank : 151)
Query Neighborhood Hits	376	Target Neighborhood Hits	753	Shared Neighborhood Hits	87
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

RUSC2_MOUSE
NC score	0.046950 (rank : 519)	θ value	4.03905 (rank : 296)
Query Neighborhood Hits	376	Target Neighborhood Hits	305	Shared Neighborhood Hits	63
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

ANK2_HUMAN
NC score	0.046546 (rank : 520)	θ value	0.0252991 (rank : 102)
Query Neighborhood Hits	376	Target Neighborhood Hits	1615	Shared Neighborhood Hits	144
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

EPN3_MOUSE
NC score	0.046216 (rank : 521)	θ value	0.279714 (rank : 143)
Query Neighborhood Hits	376	Target Neighborhood Hits	312	Shared Neighborhood Hits	59
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

F100B_MOUSE
NC score	0.045620 (rank : 522)	θ value	0.163984 (rank : 131)
Query Neighborhood Hits	376	Target Neighborhood Hits	91	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BQH4, Q3UMH5	Gene names	Fam100b
Domain Architecture	No domain graphic available
Description	Protein FAM100B.

NSD1_HUMAN
NC score	0.045579 (rank : 523)	θ value	5.27518 (rank : 307)
Query Neighborhood Hits	376	Target Neighborhood Hits	427	Shared Neighborhood Hits	58
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

T22D4_HUMAN
NC score	0.045363 (rank : 524)	θ value	0.62314 (rank : 183)
Query Neighborhood Hits	376	Target Neighborhood Hits	403	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

DOCK4_HUMAN
NC score	0.044874 (rank : 525)	θ value	0.163984 (rank : 130)
Query Neighborhood Hits	376	Target Neighborhood Hits	237	Shared Neighborhood Hits	54
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

SETBP_MOUSE
NC score	0.044658 (rank : 526)	θ value	5.27518 (rank : 310)
Query Neighborhood Hits	376	Target Neighborhood Hits	352	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

K1210_HUMAN
NC score	0.043357 (rank : 527)	θ value	8.99809 (rank : 365)
Query Neighborhood Hits	376	Target Neighborhood Hits	219	Shared Neighborhood Hits	39
SwissProt Accessions	Q9ULL0, Q5JPN4	Gene names	KIAA1210
Domain Architecture	No domain graphic available
Description	Protein KIAA1210.

BAZ2A_HUMAN
NC score	0.043075 (rank : 528)	θ value	6.88961 (rank : 317)
Query Neighborhood Hits	376	Target Neighborhood Hits	780	Shared Neighborhood Hits	94
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

DOCK4_MOUSE
NC score	0.042789 (rank : 529)	θ value	1.06291 (rank : 202)
Query Neighborhood Hits	376	Target Neighborhood Hits	210	Shared Neighborhood Hits	46
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

DCP1A_HUMAN
NC score	0.042559 (rank : 530)	θ value	1.38821 (rank : 215)
Query Neighborhood Hits	376	Target Neighborhood Hits	228	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NPI6	Gene names	DCP1A, SMIF
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (Smad4-interacting transcriptional co-activator).

ZN409_HUMAN
NC score	0.042552 (rank : 531)	θ value	0.00390308 (rank : 84)
Query Neighborhood Hits	376	Target Neighborhood Hits	842	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UPU6	Gene names	ZNF409, KIAA1056
Domain Architecture	No domain graphic available
Description	Zinc finger protein 409.

SYNP2_HUMAN
NC score	0.042371 (rank : 532)	θ value	2.36792 (rank : 258)
Query Neighborhood Hits	376	Target Neighborhood Hits	323	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

MEGF9_MOUSE
NC score	0.042349 (rank : 533)	θ value	0.47712 (rank : 171)
Query Neighborhood Hits	376	Target Neighborhood Hits	896	Shared Neighborhood Hits	103
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

ZAR1_HUMAN
NC score	0.042080 (rank : 534)	θ value	0.47712 (rank : 176)
Query Neighborhood Hits	376	Target Neighborhood Hits	163	Shared Neighborhood Hits	21
SwissProt Accessions	Q86SH2	Gene names	ZAR1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

CD248_MOUSE
NC score	0.041200 (rank : 535)	θ value	6.88961 (rank : 321)
Query Neighborhood Hits	376	Target Neighborhood Hits	578	Shared Neighborhood Hits	67
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

IWS1_MOUSE
NC score	0.040922 (rank : 536)	θ value	6.88961 (rank : 329)
Query Neighborhood Hits	376	Target Neighborhood Hits	1258	Shared Neighborhood Hits	92
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

K0240_MOUSE
NC score	0.040204 (rank : 537)	θ value	0.21417 (rank : 135)
Query Neighborhood Hits	376	Target Neighborhood Hits	211	Shared Neighborhood Hits	37
SwissProt Accessions	Q8CHH5	Gene names	Kiaa0240
Domain Architecture	No domain graphic available
Description	Protein KIAA0240.

SEPT9_MOUSE
NC score	0.040144 (rank : 538)	θ value	0.279714 (rank : 150)
Query Neighborhood Hits	376	Target Neighborhood Hits	238	Shared Neighborhood Hits	38
SwissProt Accessions	Q80UG5, Q3URP2, Q80TM7, Q9QYX9	Gene names	Sept9, Kiaa0991, Sint1
Domain Architecture	No domain graphic available
Description	Septin-9 (SL3-3 integration site 1 protein).

GA2L2_MOUSE
NC score	0.040050 (rank : 539)	θ value	4.03905 (rank : 286)
Query Neighborhood Hits	376	Target Neighborhood Hits	395	Shared Neighborhood Hits	64
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

CUTL1_MOUSE
NC score	0.039668 (rank : 540)	θ value	0.47712 (rank : 168)
Query Neighborhood Hits	376	Target Neighborhood Hits	1620	Shared Neighborhood Hits	124
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

TENS4_HUMAN
NC score	0.039216 (rank : 541)	θ value	0.62314 (rank : 185)
Query Neighborhood Hits	376	Target Neighborhood Hits	214	Shared Neighborhood Hits	30
SwissProt Accessions	Q8IZW8, Q71RB7, Q8WV64, Q96JV4	Gene names	TNS4, CTEN
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor (C-terminal tensin-like protein).

LARP4_MOUSE
NC score	0.039175 (rank : 542)	θ value	4.03905 (rank : 288)
Query Neighborhood Hits	376	Target Neighborhood Hits	260	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BWW4, Q3UR69	Gene names	Larp4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

ZIM10_HUMAN
NC score	0.038301 (rank : 543)	θ value	1.81305 (rank : 239)
Query Neighborhood Hits	376	Target Neighborhood Hits	577	Shared Neighborhood Hits	74
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

WNK2_HUMAN
NC score	0.037814 (rank : 544)	θ value	0.47712 (rank : 175)
Query Neighborhood Hits	376	Target Neighborhood Hits	1407	Shared Neighborhood Hits	177
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

HSF1_MOUSE
NC score	0.037752 (rank : 545)	θ value	1.81305 (rank : 229)
Query Neighborhood Hits	376	Target Neighborhood Hits	267	Shared Neighborhood Hits	45
SwissProt Accessions	P38532, O70462	Gene names	Hsf1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

GA2L2_HUMAN
NC score	0.037397 (rank : 546)	θ value	0.813845 (rank : 191)
Query Neighborhood Hits	376	Target Neighborhood Hits	175	Shared Neighborhood Hits	38
SwissProt Accessions	Q8NHY3, Q8NHY4	Gene names	GAS2L2, GAR17
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2) (GAS2-related protein on chromosome 17) (GAR17 protein).

RBBP6_MOUSE
NC score	0.037185 (rank : 547)	θ value	3.0926 (rank : 276)
Query Neighborhood Hits	376	Target Neighborhood Hits	1014	Shared Neighborhood Hits	88
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

EHMT2_MOUSE
NC score	0.036081 (rank : 548)	θ value	0.0193708 (rank : 98)
Query Neighborhood Hits	376	Target Neighborhood Hits	750	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

SASH1_HUMAN
NC score	0.035978 (rank : 549)	θ value	6.88961 (rank : 345)
Query Neighborhood Hits	376	Target Neighborhood Hits	292	Shared Neighborhood Hits	65
SwissProt Accessions	O94885, Q8TAI0, Q9H7R7	Gene names	SASH1, KIAA0790, PEPE1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat- containing protein).

MYH4_HUMAN
NC score	0.035880 (rank : 550)	θ value	0.813845 (rank : 196)
Query Neighborhood Hits	376	Target Neighborhood Hits	1377	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

FANCE_HUMAN
NC score	0.035521 (rank : 551)	θ value	0.62314 (rank : 180)
Query Neighborhood Hits	376	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HB96, Q4ZGH2	Gene names	FANCE
Domain Architecture	No domain graphic available
Description	Fanconi anemia group E protein (Protein FACE).

CAC1G_HUMAN
NC score	0.034762 (rank : 552)	θ value	0.0961366 (rank : 120)
Query Neighborhood Hits	376	Target Neighborhood Hits	587	Shared Neighborhood Hits	70
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

MYH4_MOUSE
NC score	0.034356 (rank : 553)	θ value	0.163984 (rank : 132)
Query Neighborhood Hits	376	Target Neighborhood Hits	1476	Shared Neighborhood Hits	65
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

NRX2A_HUMAN
NC score	0.034326 (rank : 554)	θ value	0.279714 (rank : 147)
Query Neighborhood Hits	376	Target Neighborhood Hits	614	Shared Neighborhood Hits	60
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

MYH9_MOUSE
NC score	0.034016 (rank : 555)	θ value	6.88961 (rank : 333)
Query Neighborhood Hits	376	Target Neighborhood Hits	1829	Shared Neighborhood Hits	72
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

SVIL_MOUSE
NC score	0.033867 (rank : 556)	θ value	3.0926 (rank : 278)
Query Neighborhood Hits	376	Target Neighborhood Hits	439	Shared Neighborhood Hits	46
SwissProt Accessions	Q8K4L3	Gene names	Svil
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

IL4RA_MOUSE
NC score	0.033510 (rank : 557)	θ value	1.38821 (rank : 221)
Query Neighborhood Hits	376	Target Neighborhood Hits	194	Shared Neighborhood Hits	30
SwissProt Accessions	P16382, O54690, Q60583, Q8CBW5	Gene names	Il4r, Il4ra
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (IL-4- binding protein) (IL4-BP)].

GAK4_HUMAN
NC score	0.033506 (rank : 558)	θ value	1.38821 (rank : 219)
Query Neighborhood Hits	376	Target Neighborhood Hits	415	Shared Neighborhood Hits	58
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

PDLI7_HUMAN
NC score	0.033486 (rank : 559)	θ value	0.0736092 (rank : 117)
Query Neighborhood Hits	376	Target Neighborhood Hits	547	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

GAK11_HUMAN
NC score	0.033317 (rank : 560)	θ value	1.38821 (rank : 218)
Query Neighborhood Hits	376	Target Neighborhood Hits	409	Shared Neighborhood Hits	57
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK2_HUMAN
NC score	0.033034 (rank : 561)	θ value	0.813845 (rank : 192)
Query Neighborhood Hits	376	Target Neighborhood Hits	406	Shared Neighborhood Hits	55
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

DNL1_HUMAN
NC score	0.033004 (rank : 562)	θ value	8.99809 (rank : 359)
Query Neighborhood Hits	376	Target Neighborhood Hits	216	Shared Neighborhood Hits	38
SwissProt Accessions	P18858	Gene names	LIG1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

SOX30_HUMAN
NC score	0.032759 (rank : 563)	θ value	0.365318 (rank : 164)
Query Neighborhood Hits	376	Target Neighborhood Hits	305	Shared Neighborhood Hits	46
SwissProt Accessions	O94993, O94995, Q8IYX6	Gene names	SOX30
Domain Architecture
Description	Transcription factor SOX-30.

MEF2B_MOUSE
NC score	0.032582 (rank : 564)	θ value	1.38821 (rank : 223)
Query Neighborhood Hits	376	Target Neighborhood Hits	218	Shared Neighborhood Hits	32
SwissProt Accessions	O55087, O55088, O55089, O55090, O55231, Q61843	Gene names	Mef2b
Domain Architecture
Description	Myocyte-specific enhancer factor 2B.

BI2L1_MOUSE
NC score	0.032487 (rank : 565)	θ value	0.365318 (rank : 154)
Query Neighborhood Hits	376	Target Neighborhood Hits	197	Shared Neighborhood Hits	27
SwissProt Accessions	Q9DBJ3	Gene names	Baiap2l1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

JIP1_MOUSE
NC score	0.032218 (rank : 566)	θ value	3.0926 (rank : 270)
Query Neighborhood Hits	376	Target Neighborhood Hits	259	Shared Neighborhood Hits	39
SwissProt Accessions	Q9WVI9, O35145, Q925J8, Q9R1H9, Q9R1Z1, Q9WVI7, Q9WVI8	Gene names	Mapk8ip1, Ib1, Jip1, Mapk8ip, Prkm8ip
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain-1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

GAK5_HUMAN
NC score	0.031945 (rank : 567)	θ value	1.06291 (rank : 206)
Query Neighborhood Hits	376	Target Neighborhood Hits	429	Shared Neighborhood Hits	54
SwissProt Accessions	P62684	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K113 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

PRDM2_HUMAN
NC score	0.031800 (rank : 568)	θ value	6.88961 (rank : 342)
Query Neighborhood Hits	376	Target Neighborhood Hits	1135	Shared Neighborhood Hits	125
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

GAK6_HUMAN
NC score	0.031434 (rank : 569)	θ value	2.36792 (rank : 246)
Query Neighborhood Hits	376	Target Neighborhood Hits	392	Shared Neighborhood Hits	55
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GOGB1_HUMAN
NC score	0.031288 (rank : 570)	θ value	0.813845 (rank : 194)
Query Neighborhood Hits	376	Target Neighborhood Hits	2297	Shared Neighborhood Hits	87
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

NPAS4_MOUSE
NC score	0.031284 (rank : 571)	θ value	8.99809 (rank : 368)
Query Neighborhood Hits	376	Target Neighborhood Hits	245	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

AAK1_HUMAN
NC score	0.030610 (rank : 572)	θ value	0.0193708 (rank : 97)
Query Neighborhood Hits	376	Target Neighborhood Hits	1077	Shared Neighborhood Hits	99
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

NUP53_MOUSE
NC score	0.030556 (rank : 573)	θ value	1.38821 (rank : 226)
Query Neighborhood Hits	376	Target Neighborhood Hits	94	Shared Neighborhood Hits	19
SwissProt Accessions	Q8R4R6, Q9D7J2	Gene names	Nup35, Mp44, Nup53
Domain Architecture	No domain graphic available
Description	Nucleoporin NUP53 (Nuclear pore complex protein Nup53) (Nucleoporin Nup35) (35 kDa nucleoporin) (Mitotic phosphoprotein 44) (MP-44).

SOX30_MOUSE
NC score	0.030311 (rank : 574)	θ value	6.88961 (rank : 348)
Query Neighborhood Hits	376	Target Neighborhood Hits	374	Shared Neighborhood Hits	55
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

CSPG5_MOUSE
NC score	0.030145 (rank : 575)	θ value	6.88961 (rank : 322)
Query Neighborhood Hits	376	Target Neighborhood Hits	211	Shared Neighborhood Hits	30
SwissProt Accessions	Q71M36, Q71M37, Q7TNT8, Q8BPJ5, Q9QY32	Gene names	Cspg5, Caleb, Ngc
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

SOX13_HUMAN
NC score	0.030094 (rank : 576)	θ value	5.27518 (rank : 311)
Query Neighborhood Hits	376	Target Neighborhood Hits	464	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

TENS4_MOUSE
NC score	0.030043 (rank : 577)	θ value	6.88961 (rank : 351)
Query Neighborhood Hits	376	Target Neighborhood Hits	225	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BZ33, Q3TCM8, Q7TNR5	Gene names	Tns4
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor.

MAGD4_HUMAN
NC score	0.029892 (rank : 578)	θ value	1.06291 (rank : 208)
Query Neighborhood Hits	376	Target Neighborhood Hits	338	Shared Neighborhood Hits	57
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

RTKN_HUMAN
NC score	0.029079 (rank : 579)	θ value	1.81305 (rank : 235)
Query Neighborhood Hits	376	Target Neighborhood Hits	97	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BST9, Q8WVN1, Q96PT6, Q9HB05	Gene names	RTKN
Domain Architecture	No domain graphic available
Description	Rhotekin.

NUMBL_HUMAN
NC score	0.029001 (rank : 580)	θ value	4.03905 (rank : 292)
Query Neighborhood Hits	376	Target Neighborhood Hits	394	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

PTC2_HUMAN
NC score	0.028762 (rank : 581)	θ value	0.0961366 (rank : 124)
Query Neighborhood Hits	376	Target Neighborhood Hits	63	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y6C5, O95341, O95856, Q5QP87, Q6UX14	Gene names	PTCH2
Domain Architecture
Description	Protein patched homolog 2 (PTC2).

ADDB_MOUSE
NC score	0.028621 (rank : 582)	θ value	5.27518 (rank : 301)
Query Neighborhood Hits	376	Target Neighborhood Hits	574	Shared Neighborhood Hits	57
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

DLG5_HUMAN
NC score	0.028510 (rank : 583)	θ value	8.99809 (rank : 358)
Query Neighborhood Hits	376	Target Neighborhood Hits	1088	Shared Neighborhood Hits	69
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

EMSY_HUMAN
NC score	0.028199 (rank : 584)	θ value	8.99809 (rank : 360)
Query Neighborhood Hits	376	Target Neighborhood Hits	296	Shared Neighborhood Hits	35
SwissProt Accessions	Q7Z589, Q4G109, Q8NBU6, Q8TE50, Q9H8I9, Q9NRH0	Gene names	EMSY, C11orf30
Domain Architecture
Description	Protein EMSY.

ZFHX2_HUMAN
NC score	0.028151 (rank : 585)	θ value	5.27518 (rank : 315)
Query Neighborhood Hits	376	Target Neighborhood Hits	1178	Shared Neighborhood Hits	93
SwissProt Accessions	Q9C0A1	Gene names	ZFHX2, KIAA1762
Domain Architecture
Description	Zinc finger homeobox protein 2.

FXL19_MOUSE
NC score	0.027966 (rank : 586)	θ value	0.279714 (rank : 145)
Query Neighborhood Hits	376	Target Neighborhood Hits	217	Shared Neighborhood Hits	28
SwissProt Accessions	Q6PB97, Q7TSH0, Q8BIB4	Gene names	Fbxl19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

C2TA_HUMAN
NC score	0.027873 (rank : 587)	θ value	1.06291 (rank : 200)
Query Neighborhood Hits	376	Target Neighborhood Hits	190	Shared Neighborhood Hits	33
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

DCX_HUMAN
NC score	0.027729 (rank : 588)	θ value	0.365318 (rank : 159)
Query Neighborhood Hits	376	Target Neighborhood Hits	141	Shared Neighborhood Hits	23
SwissProt Accessions	O43602, O43911	Gene names	DCX, DBCN, LISX
Domain Architecture
Description	Neuronal migration protein doublecortin (Lissencephalin-X) (Lis-X) (Doublin).

RASF7_MOUSE
NC score	0.027405 (rank : 589)	θ value	6.88961 (rank : 343)
Query Neighborhood Hits	376	Target Neighborhood Hits	136	Shared Neighborhood Hits	17
SwissProt Accessions	Q9DD19	Gene names	Rassf7
Domain Architecture
Description	Ras association domain-containing protein 7.

NTBP1_MOUSE
NC score	0.026484 (rank : 590)	θ value	6.88961 (rank : 335)
Query Neighborhood Hits	376	Target Neighborhood Hits	528	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BRM2, Q8CAA8	Gene names	Scyl1bp1, Ntklbp1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like-binding protein 1 (NTKL-binding protein 1) (NTKL-BP1) (mNTKL-BP1) (SCY1-like 1-binding protein 1) (SCYL1-binding protein 1) (SCYL1-BP1).

NIN_HUMAN
NC score	0.026466 (rank : 591)	θ value	1.81305 (rank : 233)
Query Neighborhood Hits	376	Target Neighborhood Hits	1416	Shared Neighborhood Hits	64
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

E2F4_HUMAN
NC score	0.025701 (rank : 592)	θ value	2.36792 (rank : 243)
Query Neighborhood Hits	376	Target Neighborhood Hits	188	Shared Neighborhood Hits	38
SwissProt Accessions	Q16254, Q12991, Q15328	Gene names	E2F4
Domain Architecture
Description	Transcription factor E2F4 (E2F-4).

NPAS4_HUMAN
NC score	0.025681 (rank : 593)	θ value	6.88961 (rank : 334)
Query Neighborhood Hits	376	Target Neighborhood Hits	214	Shared Neighborhood Hits	34
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

FOG1_MOUSE
NC score	0.025338 (rank : 594)	θ value	1.81305 (rank : 228)
Query Neighborhood Hits	376	Target Neighborhood Hits	1237	Shared Neighborhood Hits	124
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

PHLPP_HUMAN
NC score	0.024853 (rank : 595)	θ value	2.36792 (rank : 256)
Query Neighborhood Hits	376	Target Neighborhood Hits	604	Shared Neighborhood Hits	66
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

MMAC_HUMAN
NC score	0.024687 (rank : 596)	θ value	1.38821 (rank : 225)
Query Neighborhood Hits	376	Target Neighborhood Hits	76	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y4U1, Q5T157, Q9BRQ7	Gene names	MMACHC
Domain Architecture	No domain graphic available
Description	Methylmalonic aciduria and homocystinuria type C protein.

CP250_HUMAN
NC score	0.024384 (rank : 597)	θ value	0.365318 (rank : 158)
Query Neighborhood Hits	376	Target Neighborhood Hits	1805	Shared Neighborhood Hits	67
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

AAK1_MOUSE
NC score	0.024303 (rank : 598)	θ value	0.813845 (rank : 188)
Query Neighborhood Hits	376	Target Neighborhood Hits	1051	Shared Neighborhood Hits	80
SwissProt Accessions	Q3UHJ0, Q3TY53, Q6ZPZ6, Q80XP6	Gene names	Aak1, Kiaa1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

SEZ6L_HUMAN
NC score	0.024133 (rank : 599)	θ value	1.81305 (rank : 236)
Query Neighborhood Hits	376	Target Neighborhood Hits	289	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

LTB1L_MOUSE
NC score	0.023645 (rank : 600)	θ value	0.0193708 (rank : 99)
Query Neighborhood Hits	376	Target Neighborhood Hits	514	Shared Neighborhood Hits	25
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

DCX_MOUSE
NC score	0.023560 (rank : 601)	θ value	3.0926 (rank : 264)
Query Neighborhood Hits	376	Target Neighborhood Hits	124	Shared Neighborhood Hits	21
SwissProt Accessions	O88809	Gene names	Dcx, Dcn
Domain Architecture
Description	Neuronal migration protein doublecortin (Lissencephalin-X) (Lis-X) (Doublin).

GOGA6_HUMAN
NC score	0.023459 (rank : 602)	θ value	0.279714 (rank : 146)
Query Neighborhood Hits	376	Target Neighborhood Hits	1007	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

PHF20_MOUSE
NC score	0.023455 (rank : 603)	θ value	6.88961 (rank : 339)
Query Neighborhood Hits	376	Target Neighborhood Hits	513	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

SPEG_MOUSE
NC score	0.023012 (rank : 604)	θ value	0.47712 (rank : 174)
Query Neighborhood Hits	376	Target Neighborhood Hits	1959	Shared Neighborhood Hits	172
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

LTB1S_MOUSE
NC score	0.022991 (rank : 605)	θ value	0.0193708 (rank : 100)
Query Neighborhood Hits	376	Target Neighborhood Hits	479	Shared Neighborhood Hits	21
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

FREA_HUMAN
NC score	0.022981 (rank : 606)	θ value	0.365318 (rank : 160)
Query Neighborhood Hits	376	Target Neighborhood Hits	205	Shared Neighborhood Hits	32
SwissProt Accessions	O43638, Q96D28	Gene names	FKHL18, FREAC10
Domain Architecture	No domain graphic available
Description	Forkhead-related transcription factor 10 (FREAC-10) (Forkhead-like 18 protein).

UBQL3_MOUSE
NC score	0.022829 (rank : 607)	θ value	0.62314 (rank : 187)
Query Neighborhood Hits	376	Target Neighborhood Hits	120	Shared Neighborhood Hits	12
SwissProt Accessions	Q8C5U9	Gene names	Ubqln3
Domain Architecture
Description	Ubiquilin-3.

ZN687_HUMAN
NC score	0.022815 (rank : 608)	θ value	1.81305 (rank : 240)
Query Neighborhood Hits	376	Target Neighborhood Hits	1244	Shared Neighborhood Hits	92
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

NCTR2_HUMAN
NC score	0.022759 (rank : 609)	θ value	4.03905 (rank : 290)
Query Neighborhood Hits	376	Target Neighborhood Hits	99	Shared Neighborhood Hits	15
SwissProt Accessions	O95944, Q9H562, Q9H563, Q9H564, Q9UMT1, Q9UMT2	Gene names	NCR2, LY95
Domain Architecture
Description	Natural cytotoxicity triggering receptor 2 precursor (Natural killer cell p44-related protein) (NKp44) (NK-p44) (NK cell-activating receptor) (Lymphocyte antigen 95 homolog) (CD336 antigen).

DOCK3_MOUSE
NC score	0.022406 (rank : 610)	θ value	6.88961 (rank : 325)
Query Neighborhood Hits	376	Target Neighborhood Hits	93	Shared Neighborhood Hits	17
SwissProt Accessions	Q8CIQ7	Gene names	Dock3, Moca
Domain Architecture
Description	Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP protein).

COA2_HUMAN
NC score	0.022206 (rank : 611)	θ value	2.36792 (rank : 242)
Query Neighborhood Hits	376	Target Neighborhood Hits	184	Shared Neighborhood Hits	24
SwissProt Accessions	O00763, Q16852	Gene names	ACACB, ACC2, ACCB
Domain Architecture
Description	Acetyl-CoA carboxylase 2 (EC 6.4.1.2) (ACC-beta) [Includes: Biotin carboxylase (EC 6.3.4.14)].

NOTC2_MOUSE
NC score	0.022191 (rank : 612)	θ value	0.00869519 (rank : 87)
Query Neighborhood Hits	376	Target Neighborhood Hits	1069	Shared Neighborhood Hits	57
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

DOCK3_HUMAN
NC score	0.022113 (rank : 613)	θ value	6.88961 (rank : 324)
Query Neighborhood Hits	376	Target Neighborhood Hits	87	Shared Neighborhood Hits	17
SwissProt Accessions	Q8IZD9, O15017	Gene names	DOCK3, KIAA0299, MOCA
Domain Architecture
Description	Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP protein).

CAC1A_HUMAN
NC score	0.022011 (rank : 614)	θ value	0.279714 (rank : 142)
Query Neighborhood Hits	376	Target Neighborhood Hits	387	Shared Neighborhood Hits	47
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

DCC_MOUSE
NC score	0.021932 (rank : 615)	θ value	0.0961366 (rank : 121)
Query Neighborhood Hits	376	Target Neighborhood Hits	896	Shared Neighborhood Hits	69
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

LTB1L_HUMAN
NC score	0.021833 (rank : 616)	θ value	2.36792 (rank : 248)
Query Neighborhood Hits	376	Target Neighborhood Hits	553	Shared Neighborhood Hits	34
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

REST_MOUSE
NC score	0.021481 (rank : 617)	θ value	0.47712 (rank : 173)
Query Neighborhood Hits	376	Target Neighborhood Hits	1506	Shared Neighborhood Hits	64
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

CN145_HUMAN
NC score	0.021013 (rank : 618)	θ value	5.27518 (rank : 302)
Query Neighborhood Hits	376	Target Neighborhood Hits	1196	Shared Neighborhood Hits	50
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

MAST4_HUMAN
NC score	0.020876 (rank : 619)	θ value	3.0926 (rank : 272)
Query Neighborhood Hits	376	Target Neighborhood Hits	1804	Shared Neighborhood Hits	150
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

UBQL4_MOUSE
NC score	0.020847 (rank : 620)	θ value	1.06291 (rank : 214)
Query Neighborhood Hits	376	Target Neighborhood Hits	99	Shared Neighborhood Hits	18
SwissProt Accessions	Q99NB8, Q8BP88	Gene names	Ubqln4, Ubin
Domain Architecture
Description	Ubiquilin-4 (Ataxin-1 ubiquitin-like-interacting protein A1U).

LTB1S_HUMAN
NC score	0.020551 (rank : 621)	θ value	2.36792 (rank : 249)
Query Neighborhood Hits	376	Target Neighborhood Hits	502	Shared Neighborhood Hits	25
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

ETV5_MOUSE
NC score	0.020544 (rank : 622)	θ value	3.0926 (rank : 266)
Query Neighborhood Hits	376	Target Neighborhood Hits	328	Shared Neighborhood Hits	42
SwissProt Accessions	Q9CXC9, Q3TG49, Q8C0F3, Q9JHB1	Gene names	Etv5
Domain Architecture	No domain graphic available
Description	ETS translocation variant 5.

SWP70_HUMAN
NC score	0.020505 (rank : 623)	θ value	8.99809 (rank : 374)
Query Neighborhood Hits	376	Target Neighborhood Hits	973	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

NIN_MOUSE
NC score	0.020469 (rank : 624)	θ value	4.03905 (rank : 291)
Query Neighborhood Hits	376	Target Neighborhood Hits	1376	Shared Neighborhood Hits	52
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

GCC2_MOUSE
NC score	0.020445 (rank : 625)	θ value	4.03905 (rank : 287)
Query Neighborhood Hits	376	Target Neighborhood Hits	1619	Shared Neighborhood Hits	58
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

KCD18_HUMAN
NC score	0.019135 (rank : 626)	θ value	6.88961 (rank : 331)
Query Neighborhood Hits	376	Target Neighborhood Hits	117	Shared Neighborhood Hits	16
SwissProt Accessions	Q6PI47, Q53T21, Q6NW26, Q6PCD8, Q8N9B7, Q96N73	Gene names	KCTD18
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD18.

FGFP3_HUMAN
NC score	0.019114 (rank : 627)	θ value	4.03905 (rank : 285)
Query Neighborhood Hits	376	Target Neighborhood Hits	54	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TAT2, Q8NBN0	Gene names	FGFBP3, C10orf13
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor-binding protein 3 precursor (FGF-binding protein 3) (FGF-BP3) (FGFBP-3).

CCDC6_HUMAN
NC score	0.019018 (rank : 628)	θ value	6.88961 (rank : 320)
Query Neighborhood Hits	376	Target Neighborhood Hits	723	Shared Neighborhood Hits	48
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

GGA2_HUMAN
NC score	0.018916 (rank : 629)	θ value	0.365318 (rank : 161)
Query Neighborhood Hits	376	Target Neighborhood Hits	114	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UJY4, O14564, Q9NYN2, Q9UPS2	Gene names	GGA2, KIAA1080
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA2 (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (Gamma-adaptin-related protein 2) (VHS domain and ear domain of gamma-adaptin) (Vear).

CTGE6_HUMAN
NC score	0.018578 (rank : 630)	θ value	6.88961 (rank : 323)
Query Neighborhood Hits	376	Target Neighborhood Hits	650	Shared Neighborhood Hits	43
SwissProt Accessions	Q86UF2	Gene names	CTAGE6
Domain Architecture	No domain graphic available
Description	Protein cTAGE-6 (cTAGE family member 6).

FREA_MOUSE
NC score	0.018264 (rank : 631)	θ value	1.06291 (rank : 204)
Query Neighborhood Hits	376	Target Neighborhood Hits	147	Shared Neighborhood Hits	23
SwissProt Accessions	Q61574, Q8C5N7	Gene names	Fkhl18, Fkh3, Freac10
Domain Architecture	No domain graphic available
Description	Forkhead-related transcription factor 10 (FREAC-10) (Forkhead-like 18 protein) (Transcription factor FKH-3).

RAI2_MOUSE
NC score	0.017854 (rank : 632)	θ value	3.0926 (rank : 275)
Query Neighborhood Hits	376	Target Neighborhood Hits	58	Shared Neighborhood Hits	12
SwissProt Accessions	Q9QVY8	Gene names	Rai2
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 2 (3f8).

ZN687_MOUSE
NC score	0.017847 (rank : 633)	θ value	0.0563607 (rank : 114)
Query Neighborhood Hits	376	Target Neighborhood Hits	913	Shared Neighborhood Hits	63
SwissProt Accessions	Q9D2D7, Q6PAP3, Q6ZPQ9	Gene names	Znf687, Kiaa1441, Zfp687
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

ANR25_MOUSE
NC score	0.017498 (rank : 634)	θ value	8.99809 (rank : 353)
Query Neighborhood Hits	376	Target Neighborhood Hits	398	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

SYNG_HUMAN
NC score	0.017442 (rank : 635)	θ value	6.88961 (rank : 350)
Query Neighborhood Hits	376	Target Neighborhood Hits	160	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UMZ2, Q6ZT17	Gene names	AP1GBP1, SYNG
Domain Architecture	No domain graphic available
Description	AP1 subunit gamma-binding protein 1 (Gamma-synergin).

PAX9_HUMAN
NC score	0.016362 (rank : 636)	θ value	2.36792 (rank : 254)
Query Neighborhood Hits	376	Target Neighborhood Hits	92	Shared Neighborhood Hits	16
SwissProt Accessions	P55771, Q99582, Q9UQR4	Gene names	PAX9
Domain Architecture
Description	Paired box protein Pax-9.

CEP41_HUMAN
NC score	0.016351 (rank : 637)	θ value	4.03905 (rank : 283)
Query Neighborhood Hits	376	Target Neighborhood Hits	42	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BYV8, Q7Z496, Q86TM1, Q8NFU8, Q9H6A3, Q9NPV3	Gene names	TSGA14, CEP41
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 41 kDa (Cep41 protein) (Testis-specific gene A14 protein).

ZW10_MOUSE
NC score	0.015854 (rank : 638)	θ value	2.36792 (rank : 263)
Query Neighborhood Hits	376	Target Neighborhood Hits	86	Shared Neighborhood Hits	5
SwissProt Accessions	O54692, Q3TIA5, Q3ULW1, Q921H3	Gene names	Zw10
Domain Architecture	No domain graphic available
Description	Centromere/kinetochore protein zw10 homolog.

PSMF1_MOUSE
NC score	0.015741 (rank : 639)	θ value	4.03905 (rank : 294)
Query Neighborhood Hits	376	Target Neighborhood Hits	85	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BHL8, Q8C0G9	Gene names	Psmf1
Domain Architecture	No domain graphic available
Description	Proteasome inhibitor PI31 subunit.

CAC1B_MOUSE
NC score	0.015045 (rank : 640)	θ value	6.88961 (rank : 319)
Query Neighborhood Hits	376	Target Neighborhood Hits	351	Shared Neighborhood Hits	45
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

FOXK2_HUMAN
NC score	0.015014 (rank : 641)	θ value	3.0926 (rank : 268)
Query Neighborhood Hits	376	Target Neighborhood Hits	190	Shared Neighborhood Hits	25
SwissProt Accessions	Q01167, Q13622, Q13623, Q13624	Gene names	FOXK2, ILF, ILF1
Domain Architecture
Description	Forkhead box protein K2 (Interleukin enhancer-binding factor 1) (Cellular transcription factor ILF-1).

STON2_HUMAN
NC score	0.014881 (rank : 642)	θ value	6.88961 (rank : 349)
Query Neighborhood Hits	376	Target Neighborhood Hits	115	Shared Neighborhood Hits	15
SwissProt Accessions	Q8WXE9, Q6NT47, Q96RI7, Q96RU6	Gene names	STON2, STN2, STNB
Domain Architecture
Description	Stonin-2 (Stoned B).

LIMD1_HUMAN
NC score	0.014849 (rank : 643)	θ value	2.36792 (rank : 247)
Query Neighborhood Hits	376	Target Neighborhood Hits	201	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UGP4, Q9BQQ9, Q9NQ47	Gene names	LIMD1
Domain Architecture
Description	LIM domain-containing protein 1.

ERG_MOUSE
NC score	0.014722 (rank : 644)	θ value	0.62314 (rank : 179)
Query Neighborhood Hits	376	Target Neighborhood Hits	76	Shared Neighborhood Hits	8
SwissProt Accessions	P81270, Q8C5L4, Q920K7, Q920K8, Q920K9	Gene names	Erg, Erg-3
Domain Architecture
Description	Transcriptional regulator ERG.

DPOLL_MOUSE
NC score	0.014634 (rank : 645)	θ value	5.27518 (rank : 303)
Query Neighborhood Hits	376	Target Neighborhood Hits	71	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QXE2, Q9CTJ1	Gene names	Poll, Polk
Domain Architecture
Description	DNA polymerase lambda (EC 2.7.7.7) (EC 4.2.99.-) (Pol Lambda) (DNA polymerase kappa).

AATK_HUMAN
NC score	0.014423 (rank : 646)	θ value	0.47712 (rank : 166)
Query Neighborhood Hits	376	Target Neighborhood Hits	1243	Shared Neighborhood Hits	99
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

FOXC2_HUMAN
NC score	0.014276 (rank : 647)	θ value	1.38821 (rank : 217)
Query Neighborhood Hits	376	Target Neighborhood Hits	236	Shared Neighborhood Hits	29
SwissProt Accessions	Q99958	Gene names	FOXC2, FKHL14, MFH1
Domain Architecture
Description	Forkhead box protein C2 (Forkhead-related protein FKHL14) (Mesenchyme fork head protein 1) (MFH-1 protein) (Transcription factor FKH-14).

CSPG3_HUMAN
NC score	0.013983 (rank : 648)	θ value	8.99809 (rank : 357)
Query Neighborhood Hits	376	Target Neighborhood Hits	676	Shared Neighborhood Hits	58
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CNOT4_HUMAN
NC score	0.013723 (rank : 649)	θ value	8.99809 (rank : 356)
Query Neighborhood Hits	376	Target Neighborhood Hits	207	Shared Neighborhood Hits	21
SwissProt Accessions	O95628, O95339, O95627, Q8IYM7, Q8NCL0, Q9NPQ1, Q9NZN6	Gene names	CNOT4, NOT4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

PAX5_MOUSE
NC score	0.013675 (rank : 650)	θ value	6.88961 (rank : 338)
Query Neighborhood Hits	376	Target Neighborhood Hits	106	Shared Neighborhood Hits	16
SwissProt Accessions	Q02650	Gene names	Pax5, Pax-5
Domain Architecture
Description	Paired box protein Pax-5 (B-cell-specific transcription factor) (BSAP).

PAX5_HUMAN
NC score	0.013583 (rank : 651)	θ value	6.88961 (rank : 337)
Query Neighborhood Hits	376	Target Neighborhood Hits	106	Shared Neighborhood Hits	15
SwissProt Accessions	Q02548, O75933	Gene names	PAX5
Domain Architecture
Description	Paired box protein Pax-5 (B-cell-specific transcription factor) (BSAP).

ADA12_MOUSE
NC score	0.013372 (rank : 652)	θ value	0.365318 (rank : 153)
Query Neighborhood Hits	376	Target Neighborhood Hits	474	Shared Neighborhood Hits	55
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

TSH2_HUMAN
NC score	0.012950 (rank : 653)	θ value	1.06291 (rank : 213)
Query Neighborhood Hits	376	Target Neighborhood Hits	479	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NRE2, Q4VXM4, Q6N003, Q8N260	Gene names	TSHZ2, C20orf17, TSH2, ZNF218
Domain Architecture	No domain graphic available
Description	Teashirt homolog 2 (Zinc finger protein 218) (Ovarian cancer-related protein 10-2) (OVC10-2).

FOXK1_MOUSE
NC score	0.012622 (rank : 654)	θ value	3.0926 (rank : 267)
Query Neighborhood Hits	376	Target Neighborhood Hits	215	Shared Neighborhood Hits	24
SwissProt Accessions	P42128, O35939	Gene names	Foxk1, Mnf
Domain Architecture
Description	Forkhead box protein K1 (Myocyte nuclear factor) (MNF).

PIGQ_HUMAN
NC score	0.012235 (rank : 655)	θ value	6.88961 (rank : 340)
Query Neighborhood Hits	376	Target Neighborhood Hits	84	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BRB3, O14927, Q96G00, Q96S22, Q9UJH4	Gene names	PIGQ, GPI1
Domain Architecture
Description	Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q (EC 2.4.1.198) (Phosphatidylinositol-glycan biosynthesis class Q protein) (PIG-Q) (N-acetylglucosamyl transferase component GPI1).

TFE2_MOUSE
NC score	0.011770 (rank : 656)	θ value	3.0926 (rank : 279)
Query Neighborhood Hits	376	Target Neighborhood Hits	118	Shared Neighborhood Hits	14
SwissProt Accessions	P15806, Q3U153, Q8CAH9, Q8VCY4, Q922S2, Q99MB8, Q9CYJ4	Gene names	Tcf3, Alf2, Me2, Tcfe2a
Domain Architecture	No domain graphic available
Description	Transcription factor E2-alpha (Immunoglobulin enhancer-binding factor E12/E47) (Transcription factor 3) (TCF-3) (Transcription factor A1).

OBSCN_HUMAN
NC score	0.011678 (rank : 657)	θ value	4.03905 (rank : 293)
Query Neighborhood Hits	376	Target Neighborhood Hits	1931	Shared Neighborhood Hits	114
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

ERG_HUMAN
NC score	0.011619 (rank : 658)	θ value	3.0926 (rank : 265)
Query Neighborhood Hits	376	Target Neighborhood Hits	86	Shared Neighborhood Hits	8
SwissProt Accessions	P11308, Q16113	Gene names	ERG
Domain Architecture
Description	Transcriptional regulator ERG (Transforming protein ERG).

TLE4_MOUSE
NC score	0.011291 (rank : 659)	θ value	5.27518 (rank : 313)
Query Neighborhood Hits	376	Target Neighborhood Hits	482	Shared Neighborhood Hits	41
SwissProt Accessions	Q62441, Q9JKQ9	Gene names	Tle4, Grg4
Domain Architecture
Description	Transducin-like enhancer protein 4 (Groucho-related protein 4) (Grg- 4).

MKRN3_HUMAN
NC score	0.011275 (rank : 660)	θ value	1.38821 (rank : 224)
Query Neighborhood Hits	376	Target Neighborhood Hits	165	Shared Neighborhood Hits	8
SwissProt Accessions	Q13064	Gene names	MKRN3, RNF63, ZNF127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127) (RING finger protein 63).

SATB1_MOUSE
NC score	0.011258 (rank : 661)	θ value	6.88961 (rank : 347)
Query Neighborhood Hits	376	Target Neighborhood Hits	130	Shared Neighborhood Hits	17
SwissProt Accessions	Q60611	Gene names	Satb1
Domain Architecture
Description	DNA-binding protein SATB1 (Special AT-rich sequence-binding protein 1).

TLE4_HUMAN
NC score	0.011100 (rank : 662)	θ value	5.27518 (rank : 312)
Query Neighborhood Hits	376	Target Neighborhood Hits	477	Shared Neighborhood Hits	41
SwissProt Accessions	Q04727, Q5T1Y2, Q9BZ07, Q9BZ08, Q9BZ09, Q9NSL3, Q9ULF9	Gene names	TLE4, KIAA1261
Domain Architecture
Description	Transducin-like enhancer protein 4.

SATB1_HUMAN
NC score	0.011053 (rank : 663)	θ value	6.88961 (rank : 346)
Query Neighborhood Hits	376	Target Neighborhood Hits	130	Shared Neighborhood Hits	16
SwissProt Accessions	Q01826	Gene names	SATB1
Domain Architecture
Description	DNA-binding protein SATB1 (Special AT-rich sequence-binding protein 1).

SH22A_MOUSE
NC score	0.010912 (rank : 664)	θ value	4.03905 (rank : 297)
Query Neighborhood Hits	376	Target Neighborhood Hits	179	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QXK9, Q9JHP6	Gene names	Sh2d2a, Lad, Ribp
Domain Architecture
Description	SH2 domain protein 2A (Lck-associated adapter protein) (Lad) (Rlk/Itk- binding protein) (Ribp).

FA61A_MOUSE
NC score	0.010903 (rank : 665)	θ value	8.99809 (rank : 361)
Query Neighborhood Hits	376	Target Neighborhood Hits	81	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K2F8, Q9CTG8	Gene names	Fam61a
Domain Architecture	No domain graphic available
Description	Protein FAM61A.

TBX2_HUMAN
NC score	0.010713 (rank : 666)	θ value	2.36792 (rank : 260)
Query Neighborhood Hits	376	Target Neighborhood Hits	195	Shared Neighborhood Hits	24
SwissProt Accessions	Q13207, Q16424, Q7Z647	Gene names	TBX2
Domain Architecture
Description	T-box transcription factor TBX2 (T-box protein 2).

KSR2_HUMAN
NC score	0.010536 (rank : 667)	θ value	1.06291 (rank : 207)
Query Neighborhood Hits	376	Target Neighborhood Hits	920	Shared Neighborhood Hits	56
SwissProt Accessions	Q6VAB6, Q8N775	Gene names	KSR2
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-2 (hKSR2).

TAF9_MOUSE
NC score	0.010379 (rank : 668)	θ value	8.99809 (rank : 375)
Query Neighborhood Hits	376	Target Neighborhood Hits	69	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VI33, Q32P09, Q80XS3, Q9CV61	Gene names	Taf9, Taf2g
Domain Architecture
Description	Transcription initiation factor TFIID subunit 9 (Transcription initiation factor TFIID 31 kDa subunit) (TAFII-31) (TAFII-32) (TAFII32).

ANTR2_HUMAN
NC score	0.009204 (rank : 669)	θ value	4.03905 (rank : 280)
Query Neighborhood Hits	376	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	P58335, Q59E98, Q5JPE9, Q86UI1, Q8N4J8, Q8NB13, Q96NC7	Gene names	ANTXR2, CMG2
Domain Architecture
Description	Anthrax toxin receptor 2 precursor (Capillary morphogenesis gene 2 protein) (CMG-2).

ZF106_MOUSE
NC score	0.008996 (rank : 670)	θ value	5.27518 (rank : 314)
Query Neighborhood Hits	376	Target Neighborhood Hits	472	Shared Neighborhood Hits	26
SwissProt Accessions	O88466, O55185, O88465, O88467, Q792M1, Q792P4, Q8CDZ8, Q8R3I4, Q9ESU3	Gene names	Zfp106, H3a, Sh3bp3, Sirm, Znf474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 (Zfp-106) (Zinc finger protein 474) (H3a minor histocompatibility antigen) (Son of insulin receptor mutant).

ULK1_MOUSE
NC score	0.008720 (rank : 671)	θ value	0.0431538 (rank : 113)
Query Neighborhood Hits	376	Target Neighborhood Hits	1214	Shared Neighborhood Hits	80
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

ROCK2_MOUSE
NC score	0.008711 (rank : 672)	θ value	4.03905 (rank : 295)
Query Neighborhood Hits	376	Target Neighborhood Hits	2072	Shared Neighborhood Hits	65
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

CAMKV_HUMAN
NC score	0.008500 (rank : 673)	θ value	0.62314 (rank : 177)
Query Neighborhood Hits	376	Target Neighborhood Hits	1084	Shared Neighborhood Hits	68
SwissProt Accessions	Q8NCB2, Q6FIB8, Q8NBS8, Q8NC85, Q8NDU4, Q8WTT8, Q9BQC9, Q9H0Q5	Gene names	CAMKV
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

ZN516_MOUSE
NC score	0.008429 (rank : 674)	θ value	0.0330416 (rank : 112)
Query Neighborhood Hits	376	Target Neighborhood Hits	1197	Shared Neighborhood Hits	83
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

GP108_MOUSE
NC score	0.008314 (rank : 675)	θ value	8.99809 (rank : 362)
Query Neighborhood Hits	376	Target Neighborhood Hits	85	Shared Neighborhood Hits	13
SwissProt Accessions	Q91WD0, Q8BXE9, Q925B1	Gene names	Gpr108, Lustr2
Domain Architecture	No domain graphic available
Description	Protein GPR108 precursor (Lung seven transmembrane receptor 2).

PANK1_HUMAN
NC score	0.008292 (rank : 676)	θ value	5.27518 (rank : 308)
Query Neighborhood Hits	376	Target Neighborhood Hits	75	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TE04, Q7RTX6, Q7Z495, Q8TBQ8	Gene names	PANK1, PANK
Domain Architecture
Description	Pantothenate kinase 1 (EC 2.7.1.33) (Pantothenic acid kinase 1) (hPanK1) (hPanK).

PAX7_HUMAN
NC score	0.007467 (rank : 677)	θ value	1.06291 (rank : 212)
Query Neighborhood Hits	376	Target Neighborhood Hits	456	Shared Neighborhood Hits	23
SwissProt Accessions	P23759	Gene names	PAX7, HUP1
Domain Architecture
Description	Paired box protein Pax-7 (HUP1).

PAX7_MOUSE
NC score	0.006116 (rank : 678)	θ value	2.36792 (rank : 253)
Query Neighborhood Hits	376	Target Neighborhood Hits	422	Shared Neighborhood Hits	17
SwissProt Accessions	P47239, Q9ES16	Gene names	Pax7, Pax-7
Domain Architecture	No domain graphic available
Description	Paired box protein Pax-7.

RX_MOUSE
NC score	0.006031 (rank : 679)	θ value	6.88961 (rank : 344)
Query Neighborhood Hits	376	Target Neighborhood Hits	429	Shared Neighborhood Hits	30
SwissProt Accessions	O35602, O08748	Gene names	Rax, Rx
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

ZEP2_HUMAN
NC score	0.005658 (rank : 680)	θ value	2.36792 (rank : 262)
Query Neighborhood Hits	376	Target Neighborhood Hits	937	Shared Neighborhood Hits	42
SwissProt Accessions	P31629, Q02646, Q5THT5, Q9NS05	Gene names	HIVEP2
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 (HIV- EP2) (MHC-binding protein 2) (MBP-2).

MAST1_HUMAN
NC score	0.005479 (rank : 681)	θ value	1.06291 (rank : 209)
Query Neighborhood Hits	376	Target Neighborhood Hits	1146	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

M3KL4_HUMAN
NC score	0.005352 (rank : 682)	θ value	3.0926 (rank : 271)
Query Neighborhood Hits	376	Target Neighborhood Hits	1087	Shared Neighborhood Hits	48
SwissProt Accessions	Q5TCX8, Q5TCX7, Q5TCX9, Q8WWN1, Q8WWN2, Q96JM1	Gene names	MLK4, KIAA1804
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase 4).

EPAS1_MOUSE
NC score	0.004960 (rank : 683)	θ value	6.88961 (rank : 326)
Query Neighborhood Hits	376	Target Neighborhood Hits	94	Shared Neighborhood Hits	10
SwissProt Accessions	P97481, O08787, O55046	Gene names	Epas1, Hif2a
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Hypoxia- inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (MHLF) (HIF-related factor) (HRF).

MRCKG_HUMAN
NC score	0.004857 (rank : 684)	θ value	8.99809 (rank : 367)
Query Neighborhood Hits	376	Target Neighborhood Hits	1519	Shared Neighborhood Hits	57
SwissProt Accessions	Q6DT37, O00565	Gene names	CDC42BPG
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

HXD3_HUMAN
NC score	0.004359 (rank : 685)	θ value	8.99809 (rank : 364)
Query Neighborhood Hits	376	Target Neighborhood Hits	433	Shared Neighborhood Hits	38
SwissProt Accessions	P31249, Q99955, Q9BSC5	Gene names	HOXD3, HOX4A
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4A).

MK15_HUMAN
NC score	0.003593 (rank : 686)	θ value	0.813845 (rank : 195)
Query Neighborhood Hits	376	Target Neighborhood Hits	1038	Shared Neighborhood Hits	51
SwissProt Accessions	Q8TD08, Q2TCF9, Q8N362	Gene names	MAPK15, ERK8
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 8).

HXD3_MOUSE
NC score	0.003475 (rank : 687)	θ value	5.27518 (rank : 304)
Query Neighborhood Hits	376	Target Neighborhood Hits	435	Shared Neighborhood Hits	36
SwissProt Accessions	P09027, Q3UUD3	Gene names	Hoxd3, Hox-4.1, Hoxd-3
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4.1) (Homeobox protein MH-19).

SEM4D_MOUSE
NC score	0.003266 (rank : 688)	θ value	8.99809 (rank : 372)
Query Neighborhood Hits	376	Target Neighborhood Hits	143	Shared Neighborhood Hits	10
SwissProt Accessions	O09126	Gene names	Sema4d, Semacl2, Semaj
Domain Architecture
Description	Semaphorin-4D precursor (Semaphorin J) (Sema J) (Semaphorin C-like 2) (M-Sema G).

TNR4_MOUSE
NC score	0.002744 (rank : 689)	θ value	8.99809 (rank : 376)
Query Neighborhood Hits	376	Target Neighborhood Hits	137	Shared Neighborhood Hits	5
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

PTPRG_HUMAN
NC score	0.002647 (rank : 690)	θ value	3.0926 (rank : 274)
Query Neighborhood Hits	376	Target Neighborhood Hits	231	Shared Neighborhood Hits	18
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PK3CB_HUMAN
NC score	0.002191 (rank : 691)	θ value	6.88961 (rank : 341)
Query Neighborhood Hits	376	Target Neighborhood Hits	43	Shared Neighborhood Hits	2
SwissProt Accessions	P42338	Gene names	PIK3CB
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit beta) (PtdIns-3-kinase p110) (PI3K) (PI3Kbeta).

EPHB6_HUMAN
NC score	0.001579 (rank : 692)	θ value	2.36792 (rank : 244)
Query Neighborhood Hits	376	Target Neighborhood Hits	912	Shared Neighborhood Hits	31
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

BMP6_MOUSE
NC score	0.001370 (rank : 693)	θ value	6.88961 (rank : 318)
Query Neighborhood Hits	376	Target Neighborhood Hits	84	Shared Neighborhood Hits	7
SwissProt Accessions	P20722	Gene names	Bmp6, Bmp-6, Vgr1
Domain Architecture
Description	Bone morphogenetic protein 6 precursor (BMP-6) (VG-1-related protein) (VGR-1).

MTR1L_HUMAN
NC score	0.000395 (rank : 694)	θ value	1.06291 (rank : 211)
Query Neighborhood Hits	376	Target Neighborhood Hits	1180	Shared Neighborhood Hits	51
SwissProt Accessions	Q13585	Gene names	GPR50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).

RXRA_HUMAN
NC score	0.000285 (rank : 695)	θ value	8.99809 (rank : 371)
Query Neighborhood Hits	376	Target Neighborhood Hits	223	Shared Neighborhood Hits	15
SwissProt Accessions	P19793, Q2V504	Gene names	RXRA, NR2B1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

HXB13_MOUSE
NC score	0.000071 (rank : 696)	θ value	6.88961 (rank : 328)
Query Neighborhood Hits	376	Target Neighborhood Hits	384	Shared Neighborhood Hits	16
SwissProt Accessions	P70321, Q80Y12	Gene names	Hoxb13
Domain Architecture
Description	Homeobox protein Hox-B13.

LTK_MOUSE
NC score	-0.001481 (rank : 697)	θ value	2.36792 (rank : 250)
Query Neighborhood Hits	376	Target Neighborhood Hits	770	Shared Neighborhood Hits	20
SwissProt Accessions	P08923	Gene names	Ltk
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1).

EGR4_HUMAN
NC score	-0.001686 (rank : 698)	θ value	1.06291 (rank : 203)
Query Neighborhood Hits	376	Target Neighborhood Hits	939	Shared Neighborhood Hits	37
SwissProt Accessions	Q05215	Gene names	EGR4
Domain Architecture
Description	Early growth response protein 4 (EGR-4) (AT133).

GLI2_HUMAN
NC score	-0.002206 (rank : 699)	θ value	1.38821 (rank : 220)
Query Neighborhood Hits	376	Target Neighborhood Hits	971	Shared Neighborhood Hits	51
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

TIEG3_MOUSE
NC score	-0.003275 (rank : 700)	θ value	2.36792 (rank : 261)
Query Neighborhood Hits	376	Target Neighborhood Hits	774	Shared Neighborhood Hits	26
SwissProt Accessions	Q8K1S5, Q8BI37	Gene names	Tieg3, Tieg2b
Domain Architecture
Description	Transforming growth factor-beta-inducible early growth response protein 3 (TGFB-inducible early growth response protein 3) (TIEG-3) (TGFB-inducible early growth response protein 2b).