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Network neighborhood for query Sequence : FXL19_MOUSE

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FXL19_MOUSE
SwissProt Accessions	Q6PB97, Q7TSH0, Q8BIB4	Gene names	Fbxl19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

FXL19_HUMAN
θ value	0 (rank : 1)	NC score	0.983322 (rank : 2)
Query Neighborhood Hits	217	Target Neighborhood Hits	147	Shared Neighborhood Hits	116
SwissProt Accessions	Q6PCT2, Q8N789, Q9NT14	Gene names	FBXL19, FBL19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

FXL19_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	217	Target Neighborhood Hits	217	Shared Neighborhood Hits	217
SwissProt Accessions	Q6PB97, Q7TSH0, Q8BIB4	Gene names	Fbxl19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

JHD1B_MOUSE
θ value	7.66637e-92 (rank : 3)	NC score	0.763533 (rank : 4)
Query Neighborhood Hits	217	Target Neighborhood Hits	214	Shared Neighborhood Hits	63
SwissProt Accessions	Q6P1G2, Q3V396, Q6PFD0, Q6ZPE8, Q9CSF7, Q9QZN6	Gene names	Fbxl10, Fbl10, Jhdm1b, Kiaa3014
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10).

JHD1B_HUMAN
θ value	1.70789e-91 (rank : 4)	NC score	0.766350 (rank : 3)
Query Neighborhood Hits	217	Target Neighborhood Hits	178	Shared Neighborhood Hits	59
SwissProt Accessions	Q8NHM5, Q8NCI2, Q96HC7, Q96SL0, Q96T03, Q9NS96, Q9UF75	Gene names	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (Protein JEMMA) (Jumonji domain-containing EMSY-interactor methyltransferase motif protein) (CXXC-type zinc finger protein 2) (Protein-containing CXXC domain 2).

JHD1A_HUMAN
θ value	1.11217e-74 (rank : 5)	NC score	0.748375 (rank : 5)
Query Neighborhood Hits	217	Target Neighborhood Hits	133	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y2K7, Q49A21, Q4G0M3, Q69YY8, Q9BVH5, Q9H7H5, Q9UK66	Gene names	FBXL11, FBL7, JHDM1A, KIAA1004
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina).

JHD1A_MOUSE
θ value	2.47765e-74 (rank : 6)	NC score	0.746770 (rank : 6)
Query Neighborhood Hits	217	Target Neighborhood Hits	134	Shared Neighborhood Hits	52
SwissProt Accessions	P59997, Q3U1M5, Q3UR56, Q3V3Q1, Q69ZT4	Gene names	Fbxl11, Jhdm1a, Kiaa1004
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11).

FXL20_MOUSE
θ value	1.02475e-11 (rank : 7)	NC score	0.542843 (rank : 9)
Query Neighborhood Hits	217	Target Neighborhood Hits	78	Shared Neighborhood Hits	42
SwissProt Accessions	Q9CZV8, Q8BZ95	Gene names	Fbxl20, Fbl2
Domain Architecture
Description	F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like).

FXL20_HUMAN
θ value	1.33837e-11 (rank : 8)	NC score	0.543216 (rank : 8)
Query Neighborhood Hits	217	Target Neighborhood Hits	77	Shared Neighborhood Hits	42
SwissProt Accessions	Q96IG2	Gene names	FBXL20, FBL2
Domain Architecture
Description	F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like).

FBXL7_HUMAN
θ value	1.133e-10 (rank : 9)	NC score	0.564583 (rank : 7)
Query Neighborhood Hits	217	Target Neighborhood Hits	91	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UJT9, O94926	Gene names	FBXL7, FBL6, FBL7, KIAA0840
Domain Architecture
Description	F-box/LRR-repeat protein 7 (F-box and leucine-rich repeat protein 7) (F-box protein FBL6/FBL7).

FBXL2_MOUSE
θ value	2.52405e-10 (rank : 10)	NC score	0.528571 (rank : 10)
Query Neighborhood Hits	217	Target Neighborhood Hits	83	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BH16, Q8BXM4	Gene names	Fbxl2, Fbl2
Domain Architecture
Description	F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2).

FXL14_HUMAN
θ value	3.29651e-10 (rank : 11)	NC score	0.523813 (rank : 12)
Query Neighborhood Hits	217	Target Neighborhood Hits	71	Shared Neighborhood Hits	40
SwissProt Accessions	Q8N1E6	Gene names	FBXL14, FBL14
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 14 (F-box and leucine-rich repeat protein 14).

FXL14_MOUSE
θ value	3.29651e-10 (rank : 12)	NC score	0.524698 (rank : 11)
Query Neighborhood Hits	217	Target Neighborhood Hits	72	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BID8, Q3U2Q9, Q8R5H7, Q8VDT7, Q922N5	Gene names	Fbxl14, Fbl14, Ppa
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 14 (F-box and leucine-rich repeat protein 14).

FBXL2_HUMAN
θ value	2.79066e-09 (rank : 13)	NC score	0.520039 (rank : 13)
Query Neighborhood Hits	217	Target Neighborhood Hits	77	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UKC9, Q9NVQ8, Q9UK27, Q9UKA5, Q9Y3Y9	Gene names	FBXL2, FBL2, FBL3
Domain Architecture
Description	F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2) (F-box protein FBL2/FBL3).

DNMT1_MOUSE
θ value	4.76016e-09 (rank : 14)	NC score	0.390334 (rank : 22)
Query Neighborhood Hits	217	Target Neighborhood Hits	137	Shared Neighborhood Hits	25
SwissProt Accessions	P13864, P97413, Q80ZU3, Q9CSC6, Q9QXX6	Gene names	Dnmt1, Dnmt, Met1, Uim
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase MmuI) (DNA MTase MmuI) (MCMT) (M.MmuI) (Met-1).

DNMT1_HUMAN
θ value	3.08544e-08 (rank : 15)	NC score	0.356500 (rank : 25)
Query Neighborhood Hits	217	Target Neighborhood Hits	401	Shared Neighborhood Hits	40
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

FXL13_MOUSE
θ value	4.0297e-08 (rank : 16)	NC score	0.502218 (rank : 16)
Query Neighborhood Hits	217	Target Neighborhood Hits	70	Shared Neighborhood Hits	42
SwissProt Accessions	Q8CDU4, Q8CDE9	Gene names	Fbxl13
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 13 (F-box and leucine-rich repeat protein 13).

MLL4_HUMAN
θ value	1.99992e-07 (rank : 17)	NC score	0.253568 (rank : 38)
Query Neighborhood Hits	217	Target Neighborhood Hits	722	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

CXCC1_HUMAN
θ value	2.61198e-07 (rank : 18)	NC score	0.345190 (rank : 28)
Query Neighborhood Hits	217	Target Neighborhood Hits	143	Shared Neighborhood Hits	24
SwissProt Accessions	Q9P0U4, Q8N2W4, Q96BC8, Q9P2V7	Gene names	CXXC1, CGBP, PCCX1, PHF18
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

CXCC1_MOUSE
θ value	2.61198e-07 (rank : 19)	NC score	0.348118 (rank : 27)
Query Neighborhood Hits	217	Target Neighborhood Hits	124	Shared Neighborhood Hits	25
SwissProt Accessions	Q9CWW7	Gene names	Cxxc1, Cgbp, Pccx1
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

FBX37_MOUSE
θ value	9.92553e-07 (rank : 20)	NC score	0.437496 (rank : 21)
Query Neighborhood Hits	217	Target Neighborhood Hits	37	Shared Neighborhood Hits	28
SwissProt Accessions	Q91W61	Gene names	Fbxl15, Fbxo37
Domain Architecture	No domain graphic available
Description	F-box only protein 37 (F-box/LRR-repeat protein 15).

MBD1_HUMAN
θ value	1.29631e-06 (rank : 21)	NC score	0.366222 (rank : 24)
Query Neighborhood Hits	217	Target Neighborhood Hits	77	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UIS9, O15248, O95241, Q7Z7B5, Q8N4W4, Q9UNZ6, Q9UNZ7, Q9UNZ8, Q9UNZ9	Gene names	MBD1, PCM1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 1 (Methyl-CpG-binding protein MBD1) (Protein containing methyl-CpG-binding domain 1).

FBX37_HUMAN
θ value	1.69304e-06 (rank : 22)	NC score	0.472283 (rank : 18)
Query Neighborhood Hits	217	Target Neighborhood Hits	38	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H469, Q49AL7, Q5JWA5	Gene names	FBXL15, FBXO37
Domain Architecture	No domain graphic available
Description	F-box only protein 37 (F-box/LRR-repeat protein 15).

FXL13_HUMAN
θ value	2.88788e-06 (rank : 23)	NC score	0.477753 (rank : 17)
Query Neighborhood Hits	217	Target Neighborhood Hits	81	Shared Neighborhood Hits	39
SwissProt Accessions	Q8NEE6, Q6UVW7, Q6UVW8, Q75MN5, Q86UJ5, Q8N7Y4, Q8TCL2, Q8WUF9, Q8WUG0	Gene names	FBXL13, FBL13
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 13 (F-box and leucine-rich repeat protein 13).

SKP2_MOUSE
θ value	3.77169e-06 (rank : 24)	NC score	0.447250 (rank : 20)
Query Neighborhood Hits	217	Target Neighborhood Hits	69	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Z0Z3, Q8BSG7, Q8C8Y9, Q8CB22, Q99J53	Gene names	Skp2
Domain Architecture
Description	S-phase kinase-associated protein 2 (F-box protein Skp2) (Cyclin A/CDK2-associated protein p45) (F-box/WD-40 protein 1) (FWD1).

MBD1_MOUSE
θ value	4.92598e-06 (rank : 25)	NC score	0.349753 (rank : 26)
Query Neighborhood Hits	217	Target Neighborhood Hits	72	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Z2E2, Q792D6, Q8CCL9, Q9DC19	Gene names	Mbd1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 1 (Methyl-CpG-binding protein MBD1).

FXL16_HUMAN
θ value	8.40245e-06 (rank : 26)	NC score	0.510596 (rank : 15)
Query Neighborhood Hits	217	Target Neighborhood Hits	85	Shared Neighborhood Hits	33
SwissProt Accessions	Q8N461, Q2MHR2, Q96S14, Q9UJI0	Gene names	FBXL16, C16orf22, FBL16
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 16 (F-box and leucine-rich repeat protein 16).

LRC29_HUMAN
θ value	2.44474e-05 (rank : 27)	NC score	0.517672 (rank : 14)
Query Neighborhood Hits	217	Target Neighborhood Hits	37	Shared Neighborhood Hits	28
SwissProt Accessions	Q8WV35, Q9UKA0	Gene names	LRRC29, FBL9, FBXL9
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 29 (F-box/LRR-repeat protein 9) (F-box and leucine-rich repeat protein 9) (F-box protein FBL9).

SKP2_HUMAN
θ value	4.1701e-05 (rank : 28)	NC score	0.460003 (rank : 19)
Query Neighborhood Hits	217	Target Neighborhood Hits	79	Shared Neighborhood Hits	40
SwissProt Accessions	Q13309, Q8TDZ0, Q8TDZ1, Q9BV69	Gene names	SKP2, FBXL1
Domain Architecture
Description	S-phase kinase-associated protein 2 (F-box protein Skp2) (Cyclin A/CDK2-associated protein p45) (p45skp2) (F-box/LRR-repeat protein 1).

HRX_HUMAN
θ value	0.00020696 (rank : 29)	NC score	0.221580 (rank : 43)
Query Neighborhood Hits	217	Target Neighborhood Hits	825	Shared Neighborhood Hits	71
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

PRRT3_HUMAN
θ value	0.00102713 (rank : 30)	NC score	0.125215 (rank : 51)
Query Neighborhood Hits	217	Target Neighborhood Hits	998	Shared Neighborhood Hits	105
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

FXL22_MOUSE
θ value	0.00390308 (rank : 31)	NC score	0.344654 (rank : 29)
Query Neighborhood Hits	217	Target Neighborhood Hits	40	Shared Neighborhood Hits	31
SwissProt Accessions	Q8C7B6, Q8C3G3, Q8C3V6	Gene names	Fbxl22
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 22 (F-box and leucine-rich repeat protein 22).

IWS1_HUMAN
θ value	0.00390308 (rank : 32)	NC score	0.093241 (rank : 61)
Query Neighborhood Hits	217	Target Neighborhood Hits	1241	Shared Neighborhood Hits	70
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

NGEF_MOUSE
θ value	0.00390308 (rank : 33)	NC score	0.053692 (rank : 121)
Query Neighborhood Hits	217	Target Neighborhood Hits	228	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

OBSCN_HUMAN
θ value	0.00390308 (rank : 34)	NC score	0.020389 (rank : 206)
Query Neighborhood Hits	217	Target Neighborhood Hits	1931	Shared Neighborhood Hits	67
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

FBXL4_HUMAN
θ value	0.00509761 (rank : 35)	NC score	0.387545 (rank : 23)
Query Neighborhood Hits	217	Target Neighborhood Hits	54	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UKA2, O95919, Q9UJU0	Gene names	FBXL4, FBL4, FBL5
Domain Architecture
Description	F-box/LRR-repeat protein 4 (F-box and leucine-rich repeat protein 4) (F-box protein FBL4/FBL5).

NIPBL_HUMAN
θ value	0.0193708 (rank : 36)	NC score	0.070538 (rank : 78)
Query Neighborhood Hits	217	Target Neighborhood Hits	1311	Shared Neighborhood Hits	63
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

ZYX_HUMAN
θ value	0.0252991 (rank : 37)	NC score	0.040157 (rank : 149)
Query Neighborhood Hits	217	Target Neighborhood Hits	387	Shared Neighborhood Hits	28
SwissProt Accessions	Q15942	Gene names	ZYX
Domain Architecture
Description	Zyxin (Zyxin-2).

CSKI1_HUMAN
θ value	0.0431538 (rank : 38)	NC score	0.033442 (rank : 167)
Query Neighborhood Hits	217	Target Neighborhood Hits	997	Shared Neighborhood Hits	77
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

FXL12_MOUSE
θ value	0.0431538 (rank : 39)	NC score	0.329044 (rank : 30)
Query Neighborhood Hits	217	Target Neighborhood Hits	79	Shared Neighborhood Hits	40
SwissProt Accessions	Q9EPX5, Q3UVH7, Q8CDX0, Q9CY04, Q9QZN5	Gene names	Fbxl12, Fbl12
Domain Architecture
Description	F-box/LRR-repeat protein 12 (F-box and leucine-rich repeat protein 12) (F-box protein FBL12).

TACC2_HUMAN
θ value	0.0431538 (rank : 40)	NC score	0.046867 (rank : 132)
Query Neighborhood Hits	217	Target Neighborhood Hits	856	Shared Neighborhood Hits	46
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

PAK4_HUMAN
θ value	0.0563607 (rank : 41)	NC score	0.005958 (rank : 238)
Query Neighborhood Hits	217	Target Neighborhood Hits	924	Shared Neighborhood Hits	15
SwissProt Accessions	O96013, Q8N4E1, Q8NCH5, Q8NDE3, Q9BU33, Q9ULS8	Gene names	PAK4, KIAA1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

PHF10_HUMAN
θ value	0.0563607 (rank : 42)	NC score	0.111410 (rank : 52)
Query Neighborhood Hits	217	Target Neighborhood Hits	151	Shared Neighborhood Hits	25
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

PRB4S_HUMAN
θ value	0.0563607 (rank : 43)	NC score	0.076459 (rank : 67)
Query Neighborhood Hits	217	Target Neighborhood Hits	330	Shared Neighborhood Hits	39
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

TITIN_HUMAN
θ value	0.0563607 (rank : 44)	NC score	0.016660 (rank : 213)
Query Neighborhood Hits	217	Target Neighborhood Hits	2923	Shared Neighborhood Hits	74
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

FBX16_HUMAN
θ value	0.0961366 (rank : 45)	NC score	0.149867 (rank : 46)
Query Neighborhood Hits	217	Target Neighborhood Hits	51	Shared Neighborhood Hits	25
SwissProt Accessions	Q8IX29, Q3T1B4	Gene names	FBXO16, FBX16
Domain Architecture
Description	F-box only protein 16.

FBXL5_MOUSE
θ value	0.0961366 (rank : 46)	NC score	0.242149 (rank : 40)
Query Neighborhood Hits	217	Target Neighborhood Hits	103	Shared Neighborhood Hits	43
SwissProt Accessions	Q8C2S5, Q3TWC9, Q80XI5, Q8BGF5, Q8BNL3, Q8C3Q8	Gene names	Fbxl5
Domain Architecture
Description	F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5).

FBXW8_MOUSE
θ value	0.0961366 (rank : 47)	NC score	0.158100 (rank : 44)
Query Neighborhood Hits	217	Target Neighborhood Hits	162	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BIA4, Q8BI62, Q8BI75, Q8BI76, Q8CID8, Q921Z1	Gene names	Fbxw8
Domain Architecture
Description	F-box/WD repeat protein 8 (F-box and WD-40 domain protein 8).

OGFR_MOUSE
θ value	0.0961366 (rank : 48)	NC score	0.078903 (rank : 64)
Query Neighborhood Hits	217	Target Neighborhood Hits	584	Shared Neighborhood Hits	64
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

FBXL5_HUMAN
θ value	0.125558 (rank : 49)	NC score	0.232320 (rank : 42)
Query Neighborhood Hits	217	Target Neighborhood Hits	111	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UKA1, Q8NHP3, Q9NXN2, Q9P0I0, Q9P0X5, Q9UJT7, Q9UKC8	Gene names	FBXL5, FBL4, FBL5, FLR1
Domain Architecture
Description	F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5) (F-box protein FBL4/FBL5) (p45SKP2-like protein).

FXL12_HUMAN
θ value	0.125558 (rank : 50)	NC score	0.316189 (rank : 31)
Query Neighborhood Hits	217	Target Neighborhood Hits	86	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NXK8, Q9H5K4	Gene names	FBXL12, FBL12
Domain Architecture
Description	F-box/LRR-repeat protein 12 (F-box and leucine-rich repeat protein 12) (F-box protein FBL12).

PHF10_MOUSE
θ value	0.125558 (rank : 51)	NC score	0.106923 (rank : 54)
Query Neighborhood Hits	217	Target Neighborhood Hits	131	Shared Neighborhood Hits	24
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

FBXL6_MOUSE
θ value	0.163984 (rank : 52)	NC score	0.249660 (rank : 39)
Query Neighborhood Hits	217	Target Neighborhood Hits	55	Shared Neighborhood Hits	32
SwissProt Accessions	Q9QXW0, Q9JJD7	Gene names	Fbxl6, Fbl6
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 6 (F-box and leucine-rich repeat protein 6) (F-box protein FBL6).

NPBL_MOUSE
θ value	0.163984 (rank : 53)	NC score	0.073163 (rank : 73)
Query Neighborhood Hits	217	Target Neighborhood Hits	1041	Shared Neighborhood Hits	58
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

FBXL8_MOUSE
θ value	0.21417 (rank : 54)	NC score	0.137583 (rank : 49)
Query Neighborhood Hits	217	Target Neighborhood Hits	38	Shared Neighborhood Hits	28
SwissProt Accessions	Q8CIG9, Q9QZN7	Gene names	Fbxl8, Fbl8
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 8 (F-box and leucine-rich repeat protein 8) (F-box protein FBL8).

MYST3_HUMAN
θ value	0.21417 (rank : 55)	NC score	0.099528 (rank : 57)
Query Neighborhood Hits	217	Target Neighborhood Hits	772	Shared Neighborhood Hits	51
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

NCOR1_HUMAN
θ value	0.21417 (rank : 56)	NC score	0.044863 (rank : 133)
Query Neighborhood Hits	217	Target Neighborhood Hits	577	Shared Neighborhood Hits	31
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

WIRE_MOUSE
θ value	0.21417 (rank : 57)	NC score	0.073485 (rank : 71)
Query Neighborhood Hits	217	Target Neighborhood Hits	310	Shared Neighborhood Hits	41
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

3BP1_HUMAN
θ value	0.279714 (rank : 58)	NC score	0.027966 (rank : 187)
Query Neighborhood Hits	217	Target Neighborhood Hits	376	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

IER5_MOUSE
θ value	0.279714 (rank : 59)	NC score	0.066455 (rank : 87)
Query Neighborhood Hits	217	Target Neighborhood Hits	110	Shared Neighborhood Hits	14
SwissProt Accessions	O89113, Q8CGI0	Gene names	Ier5
Domain Architecture	No domain graphic available
Description	Immediate early response gene 5 protein.

RGS3_MOUSE
θ value	0.279714 (rank : 60)	NC score	0.068132 (rank : 84)
Query Neighborhood Hits	217	Target Neighborhood Hits	1621	Shared Neighborhood Hits	119
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

CS016_HUMAN
θ value	0.365318 (rank : 61)	NC score	0.059749 (rank : 102)
Query Neighborhood Hits	217	Target Neighborhood Hits	310	Shared Neighborhood Hits	31
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

FBXL6_HUMAN
θ value	0.365318 (rank : 62)	NC score	0.238729 (rank : 41)
Query Neighborhood Hits	217	Target Neighborhood Hits	65	Shared Neighborhood Hits	29
SwissProt Accessions	Q8N531, Q9H5W9, Q9UKC7	Gene names	FBXL6, FBL6
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 6 (F-box and leucine-rich repeat protein 6) (F-box protein FBL6) (FBL6A).

FRS3_MOUSE
θ value	0.365318 (rank : 63)	NC score	0.037718 (rank : 154)
Query Neighborhood Hits	217	Target Neighborhood Hits	168	Shared Neighborhood Hits	23
SwissProt Accessions	Q91WJ0	Gene names	Frs3, Frs2b
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (FRS2-beta).

MILK1_HUMAN
θ value	0.365318 (rank : 64)	NC score	0.041914 (rank : 142)
Query Neighborhood Hits	217	Target Neighborhood Hits	427	Shared Neighborhood Hits	43
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MILK1_MOUSE
θ value	0.365318 (rank : 65)	NC score	0.058177 (rank : 105)
Query Neighborhood Hits	217	Target Neighborhood Hits	788	Shared Neighborhood Hits	83
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

PRP1_HUMAN
θ value	0.365318 (rank : 66)	NC score	0.064123 (rank : 90)
Query Neighborhood Hits	217	Target Neighborhood Hits	385	Shared Neighborhood Hits	40
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

SON_MOUSE
θ value	0.365318 (rank : 67)	NC score	0.059564 (rank : 103)
Query Neighborhood Hits	217	Target Neighborhood Hits	957	Shared Neighborhood Hits	77
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

VASP_HUMAN
θ value	0.365318 (rank : 68)	NC score	0.055563 (rank : 114)
Query Neighborhood Hits	217	Target Neighborhood Hits	201	Shared Neighborhood Hits	24
SwissProt Accessions	P50552, Q6PIZ1, Q93035	Gene names	VASP
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

CRSP7_HUMAN
θ value	0.47712 (rank : 69)	NC score	0.068491 (rank : 82)
Query Neighborhood Hits	217	Target Neighborhood Hits	247	Shared Neighborhood Hits	30
SwissProt Accessions	O95402	Gene names	CRSP7, ARC70
Domain Architecture
Description	CRSP complex subunit 7 (Cofactor required for Sp1 transcriptional activation subunit 7) (Transcriptional coactivator CRSP70) (Activator- recruited cofactor 70 kDa component) (ARC70).

FBX27_MOUSE
θ value	0.47712 (rank : 70)	NC score	0.055583 (rank : 113)
Query Neighborhood Hits	217	Target Neighborhood Hits	29	Shared Neighborhood Hits	19
SwissProt Accessions	Q6DIA9, Q3TYP0, Q8BKF7	Gene names	Fbxo27
Domain Architecture	No domain graphic available
Description	F-box only protein 27.

JPH2_HUMAN
θ value	0.47712 (rank : 71)	NC score	0.043216 (rank : 140)
Query Neighborhood Hits	217	Target Neighborhood Hits	639	Shared Neighborhood Hits	85
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

K1802_MOUSE
θ value	0.47712 (rank : 72)	NC score	0.061206 (rank : 96)
Query Neighborhood Hits	217	Target Neighborhood Hits	1596	Shared Neighborhood Hits	108
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

PHC2_MOUSE
θ value	0.47712 (rank : 73)	NC score	0.029380 (rank : 183)
Query Neighborhood Hits	217	Target Neighborhood Hits	156	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QWH1, O88463, Q8K5D9	Gene names	Phc2, Edr2, Ph2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (mPH2) (Early development regulatory protein 2) (p36).

SI1L3_HUMAN
θ value	0.47712 (rank : 74)	NC score	0.031885 (rank : 174)
Query Neighborhood Hits	217	Target Neighborhood Hits	305	Shared Neighborhood Hits	33
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

WIRE_HUMAN
θ value	0.47712 (rank : 75)	NC score	0.069787 (rank : 79)
Query Neighborhood Hits	217	Target Neighborhood Hits	329	Shared Neighborhood Hits	41
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

ASTL_HUMAN
θ value	0.62314 (rank : 76)	NC score	0.044212 (rank : 136)
Query Neighborhood Hits	217	Target Neighborhood Hits	252	Shared Neighborhood Hits	33
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

FBXW8_HUMAN
θ value	0.62314 (rank : 77)	NC score	0.146470 (rank : 47)
Query Neighborhood Hits	217	Target Neighborhood Hits	192	Shared Neighborhood Hits	31
SwissProt Accessions	Q8N3Y1, Q9UK95	Gene names	FBXW8, FBW6, FBW8, FBX29, FBXO29, FBXW6
Domain Architecture
Description	F-box/WD repeat protein 8 (F-box and WD-40 domain protein 8) (F-box only protein 29).

FOG1_MOUSE
θ value	0.62314 (rank : 78)	NC score	0.011991 (rank : 224)
Query Neighborhood Hits	217	Target Neighborhood Hits	1237	Shared Neighborhood Hits	66
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

GA2L2_MOUSE
θ value	0.62314 (rank : 79)	NC score	0.060644 (rank : 99)
Query Neighborhood Hits	217	Target Neighborhood Hits	395	Shared Neighborhood Hits	66
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

MYST3_MOUSE
θ value	0.62314 (rank : 80)	NC score	0.095641 (rank : 58)
Query Neighborhood Hits	217	Target Neighborhood Hits	688	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

VASP_MOUSE
θ value	0.62314 (rank : 81)	NC score	0.048065 (rank : 129)
Query Neighborhood Hits	217	Target Neighborhood Hits	195	Shared Neighborhood Hits	22
SwissProt Accessions	P70460, Q3TAP0, Q3TCD2, Q3U0C2, Q3UDF1, Q91VD2, Q9R214	Gene names	Vasp
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

ZYX_MOUSE
θ value	0.62314 (rank : 82)	NC score	0.034426 (rank : 164)
Query Neighborhood Hits	217	Target Neighborhood Hits	347	Shared Neighborhood Hits	25
SwissProt Accessions	Q62523, P70461	Gene names	Zyx
Domain Architecture
Description	Zyxin.

BAZ1B_MOUSE
θ value	0.813845 (rank : 83)	NC score	0.061450 (rank : 95)
Query Neighborhood Hits	217	Target Neighborhood Hits	394	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

MLL3_HUMAN
θ value	0.813845 (rank : 84)	NC score	0.105081 (rank : 55)
Query Neighborhood Hits	217	Target Neighborhood Hits	1644	Shared Neighborhood Hits	118
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MLL3_MOUSE
θ value	0.813845 (rank : 85)	NC score	0.107773 (rank : 53)
Query Neighborhood Hits	217	Target Neighborhood Hits	1399	Shared Neighborhood Hits	120
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

RX_HUMAN
θ value	0.813845 (rank : 86)	NC score	0.007013 (rank : 235)
Query Neighborhood Hits	217	Target Neighborhood Hits	423	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y2V3	Gene names	RAX, RX
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

SEM6C_HUMAN
θ value	0.813845 (rank : 87)	NC score	0.009890 (rank : 229)
Query Neighborhood Hits	217	Target Neighborhood Hits	117	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H3T2, Q5JR71, Q8WXT8, Q8WXT9, Q8WXU0, Q96JF8	Gene names	SEMA6C, KIAA1869, SEMAY
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

SON_HUMAN
θ value	0.813845 (rank : 88)	NC score	0.074189 (rank : 70)
Query Neighborhood Hits	217	Target Neighborhood Hits	1568	Shared Neighborhood Hits	116
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

YLPM1_HUMAN
θ value	0.813845 (rank : 89)	NC score	0.069616 (rank : 81)
Query Neighborhood Hits	217	Target Neighborhood Hits	670	Shared Neighborhood Hits	60
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

CSKI1_MOUSE
θ value	1.06291 (rank : 90)	NC score	0.032933 (rank : 171)
Query Neighborhood Hits	217	Target Neighborhood Hits	1031	Shared Neighborhood Hits	86
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

FA47B_HUMAN
θ value	1.06291 (rank : 91)	NC score	0.071862 (rank : 75)
Query Neighborhood Hits	217	Target Neighborhood Hits	431	Shared Neighborhood Hits	75
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

FBX41_HUMAN
θ value	1.06291 (rank : 92)	NC score	0.095511 (rank : 59)
Query Neighborhood Hits	217	Target Neighborhood Hits	475	Shared Neighborhood Hits	34
SwissProt Accessions	Q8TF61	Gene names	FBXO41, FBX41, KIAA1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

IF4B_HUMAN
θ value	1.06291 (rank : 93)	NC score	0.055775 (rank : 111)
Query Neighborhood Hits	217	Target Neighborhood Hits	417	Shared Neighborhood Hits	36
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

MDM2_MOUSE
θ value	1.06291 (rank : 94)	NC score	0.032415 (rank : 172)
Query Neighborhood Hits	217	Target Neighborhood Hits	77	Shared Neighborhood Hits	8
SwissProt Accessions	P23804, Q61040, Q64330	Gene names	Mdm2
Domain Architecture
Description	Ubiquitin-protein ligase E3 Mdm2 (EC 6.3.2.-) (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein).

PAK4_MOUSE
θ value	1.06291 (rank : 95)	NC score	0.005966 (rank : 237)
Query Neighborhood Hits	217	Target Neighborhood Hits	1098	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

PI5PA_MOUSE
θ value	1.06291 (rank : 96)	NC score	0.029416 (rank : 182)
Query Neighborhood Hits	217	Target Neighborhood Hits	331	Shared Neighborhood Hits	34
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PRB3_HUMAN
θ value	1.06291 (rank : 97)	NC score	0.063714 (rank : 91)
Query Neighborhood Hits	217	Target Neighborhood Hits	318	Shared Neighborhood Hits	41
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

WASL_HUMAN
θ value	1.06291 (rank : 98)	NC score	0.044106 (rank : 138)
Query Neighborhood Hits	217	Target Neighborhood Hits	312	Shared Neighborhood Hits	34
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

CECR2_HUMAN
θ value	1.38821 (rank : 99)	NC score	0.055620 (rank : 112)
Query Neighborhood Hits	217	Target Neighborhood Hits	543	Shared Neighborhood Hits	66
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

CXXC6_HUMAN
θ value	1.38821 (rank : 100)	NC score	0.134593 (rank : 50)
Query Neighborhood Hits	217	Target Neighborhood Hits	180	Shared Neighborhood Hits	28
SwissProt Accessions	Q8NFU7, Q5VUP7, Q7Z6B6, Q8TCR1, Q9C0I7	Gene names	CXXC6, KIAA1676, LCX
Domain Architecture	No domain graphic available
Description	CXXC-type zinc finger protein 6 (Leukemia-associated protein with a CXXC domain).

DIAP1_MOUSE
θ value	1.38821 (rank : 101)	NC score	0.028755 (rank : 185)
Query Neighborhood Hits	217	Target Neighborhood Hits	839	Shared Neighborhood Hits	38
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

FBX39_HUMAN
θ value	1.38821 (rank : 102)	NC score	0.075112 (rank : 69)
Query Neighborhood Hits	217	Target Neighborhood Hits	23	Shared Neighborhood Hits	17
SwissProt Accessions	Q8N4B4	Gene names	FBXO39, FBX39
Domain Architecture	No domain graphic available
Description	F-box only protein 39.

FBXL8_HUMAN
θ value	1.38821 (rank : 103)	NC score	0.142334 (rank : 48)
Query Neighborhood Hits	217	Target Neighborhood Hits	43	Shared Neighborhood Hits	32
SwissProt Accessions	Q96CD0, Q9NUM0	Gene names	FBXL8, FBL8
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 8 (F-box and leucine-rich repeat protein 8) (F-box protein FBL8).

IWS1_MOUSE
θ value	1.38821 (rank : 104)	NC score	0.071941 (rank : 74)
Query Neighborhood Hits	217	Target Neighborhood Hits	1258	Shared Neighborhood Hits	74
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

PHF14_MOUSE
θ value	1.38821 (rank : 105)	NC score	0.068467 (rank : 83)
Query Neighborhood Hits	217	Target Neighborhood Hits	342	Shared Neighborhood Hits	34
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

BTBDC_HUMAN
θ value	1.81305 (rank : 106)	NC score	0.042918 (rank : 141)
Query Neighborhood Hits	217	Target Neighborhood Hits	248	Shared Neighborhood Hits	27
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

FBW1B_HUMAN
θ value	1.81305 (rank : 107)	NC score	0.027246 (rank : 190)
Query Neighborhood Hits	217	Target Neighborhood Hits	327	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UKB1, Q9P2S8, Q9P2S9, Q9Y4C6	Gene names	FBXW11, BTRCP2, FBW1B, FBXW1B, KIAA0696
Domain Architecture
Description	F-box/WD repeat protein 11 (F-box/WD repeat protein 1B) (F-box and WD repeats protein beta-TrCP2).

SHAN1_HUMAN
θ value	1.81305 (rank : 108)	NC score	0.020973 (rank : 204)
Query Neighborhood Hits	217	Target Neighborhood Hits	1041	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SMRC1_HUMAN
θ value	1.81305 (rank : 109)	NC score	0.024761 (rank : 196)
Query Neighborhood Hits	217	Target Neighborhood Hits	375	Shared Neighborhood Hits	26
SwissProt Accessions	Q92922, Q6P172, Q8IWH2	Gene names	SMARCC1, BAF155
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155).

ACRO_HUMAN
θ value	2.36792 (rank : 110)	NC score	0.002933 (rank : 245)
Query Neighborhood Hits	217	Target Neighborhood Hits	291	Shared Neighborhood Hits	15
SwissProt Accessions	P10323, Q6ICK2	Gene names	ACR, ACRS
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

APS_HUMAN
θ value	2.36792 (rank : 111)	NC score	0.022348 (rank : 201)
Query Neighborhood Hits	217	Target Neighborhood Hits	162	Shared Neighborhood Hits	6
SwissProt Accessions	O14492	Gene names	APS
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

BAT2_HUMAN
θ value	2.36792 (rank : 112)	NC score	0.060842 (rank : 98)
Query Neighborhood Hits	217	Target Neighborhood Hits	931	Shared Neighborhood Hits	91
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CBP_HUMAN
θ value	2.36792 (rank : 113)	NC score	0.039200 (rank : 150)
Query Neighborhood Hits	217	Target Neighborhood Hits	941	Shared Neighborhood Hits	85
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CPSF6_HUMAN
θ value	2.36792 (rank : 114)	NC score	0.041464 (rank : 145)
Query Neighborhood Hits	217	Target Neighborhood Hits	359	Shared Neighborhood Hits	33
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

CPSF6_MOUSE
θ value	2.36792 (rank : 115)	NC score	0.041842 (rank : 143)
Query Neighborhood Hits	217	Target Neighborhood Hits	356	Shared Neighborhood Hits	34
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

CT174_HUMAN
θ value	2.36792 (rank : 116)	NC score	0.041265 (rank : 146)
Query Neighborhood Hits	217	Target Neighborhood Hits	181	Shared Neighborhood Hits	31
SwissProt Accessions	Q5JPB2, Q5TDR4, Q8TCP0	Gene names	C20orf174
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf174.

DIAP1_HUMAN
θ value	2.36792 (rank : 117)	NC score	0.030948 (rank : 177)
Query Neighborhood Hits	217	Target Neighborhood Hits	784	Shared Neighborhood Hits	43
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

FMNL_MOUSE
θ value	2.36792 (rank : 118)	NC score	0.035052 (rank : 161)
Query Neighborhood Hits	217	Target Neighborhood Hits	428	Shared Neighborhood Hits	34
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

GRIN1_MOUSE
θ value	2.36792 (rank : 119)	NC score	0.036415 (rank : 157)
Query Neighborhood Hits	217	Target Neighborhood Hits	337	Shared Neighborhood Hits	34
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

PHF14_HUMAN
θ value	2.36792 (rank : 120)	NC score	0.066464 (rank : 86)
Query Neighborhood Hits	217	Target Neighborhood Hits	447	Shared Neighborhood Hits	34
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

RBM22_HUMAN
θ value	2.36792 (rank : 121)	NC score	0.025542 (rank : 194)
Query Neighborhood Hits	217	Target Neighborhood Hits	189	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NW64, O95607	Gene names	RBM22
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor RBM22 (RNA-binding motif protein 22).

RBM22_MOUSE
θ value	2.36792 (rank : 122)	NC score	0.025542 (rank : 195)
Query Neighborhood Hits	217	Target Neighborhood Hits	189	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BHS3, Q3TJB0, Q9CXA0	Gene names	Rbm22
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor RBM22 (RNA-binding motif protein 22).

SYN1_MOUSE
θ value	2.36792 (rank : 123)	NC score	0.033652 (rank : 166)
Query Neighborhood Hits	217	Target Neighborhood Hits	363	Shared Neighborhood Hits	38
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

TGIF_HUMAN
θ value	2.36792 (rank : 124)	NC score	0.019298 (rank : 211)
Query Neighborhood Hits	217	Target Neighborhood Hits	109	Shared Neighborhood Hits	4
SwissProt Accessions	Q15583, Q6ICR0, Q8N5X9, Q9NRS0	Gene names	TGIF
Domain Architecture
Description	5'-TG-3'-interacting factor (Homeobox protein TGIF).

TRI66_HUMAN
θ value	2.36792 (rank : 125)	NC score	0.033423 (rank : 168)
Query Neighborhood Hits	217	Target Neighborhood Hits	479	Shared Neighborhood Hits	40
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TULP4_HUMAN
θ value	2.36792 (rank : 126)	NC score	0.037692 (rank : 155)
Query Neighborhood Hits	217	Target Neighborhood Hits	426	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

WASL_MOUSE
θ value	2.36792 (rank : 127)	NC score	0.044114 (rank : 137)
Query Neighborhood Hits	217	Target Neighborhood Hits	339	Shared Neighborhood Hits	36
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WBP11_HUMAN
θ value	2.36792 (rank : 128)	NC score	0.054914 (rank : 116)
Query Neighborhood Hits	217	Target Neighborhood Hits	354	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

WBP11_MOUSE
θ value	2.36792 (rank : 129)	NC score	0.056374 (rank : 109)
Query Neighborhood Hits	217	Target Neighborhood Hits	362	Shared Neighborhood Hits	37
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

AB1IP_HUMAN
θ value	3.0926 (rank : 130)	NC score	0.023513 (rank : 199)
Query Neighborhood Hits	217	Target Neighborhood Hits	213	Shared Neighborhood Hits	23
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

ARHGF_HUMAN
θ value	3.0926 (rank : 131)	NC score	0.033833 (rank : 165)
Query Neighborhood Hits	217	Target Neighborhood Hits	214	Shared Neighborhood Hits	21
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

CD5R2_MOUSE
θ value	3.0926 (rank : 132)	NC score	0.029108 (rank : 184)
Query Neighborhood Hits	217	Target Neighborhood Hits	57	Shared Neighborhood Hits	13
SwissProt Accessions	O35926, O35277	Gene names	Cdk5r2, Nck5ai
Domain Architecture
Description	Cyclin-dependent kinase 5 activator 2 precursor (CDK5 activator 2) (Cyclin-dependent kinase 5 regulatory subunit 2) (P39) (P39I).

CO4A4_HUMAN
θ value	3.0926 (rank : 133)	NC score	0.014693 (rank : 219)
Query Neighborhood Hits	217	Target Neighborhood Hits	440	Shared Neighborhood Hits	37
SwissProt Accessions	P53420	Gene names	COL4A4
Domain Architecture
Description	Collagen alpha-4(IV) chain precursor.

DCR1A_MOUSE
θ value	3.0926 (rank : 134)	NC score	0.022092 (rank : 202)
Query Neighborhood Hits	217	Target Neighborhood Hits	59	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JIC3, Q571H5, Q6GQR6	Gene names	Dclre1a, Kiaa0086, Snm1, Snm1a
Domain Architecture	No domain graphic available
Description	DNA cross-link repair 1A protein.

DOCK4_HUMAN
θ value	3.0926 (rank : 135)	NC score	0.020675 (rank : 205)
Query Neighborhood Hits	217	Target Neighborhood Hits	237	Shared Neighborhood Hits	31
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

DOCK4_MOUSE
θ value	3.0926 (rank : 136)	NC score	0.019819 (rank : 209)
Query Neighborhood Hits	217	Target Neighborhood Hits	210	Shared Neighborhood Hits	25
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

ENAH_MOUSE
θ value	3.0926 (rank : 137)	NC score	0.040817 (rank : 147)
Query Neighborhood Hits	217	Target Neighborhood Hits	919	Shared Neighborhood Hits	49
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

FBX11_HUMAN
θ value	3.0926 (rank : 138)	NC score	0.154198 (rank : 45)
Query Neighborhood Hits	217	Target Neighborhood Hits	72	Shared Neighborhood Hits	33
SwissProt Accessions	Q86XK2, Q8IXG3, Q96E90, Q9H6V8, Q9H9L1, Q9NR14, Q9UFK1, Q9UHI1, Q9UKC2	Gene names	FBXO11, FBX11, VIT1
Domain Architecture
Description	F-box only protein 11 (Vitiligo-associated protein VIT-1).

FBX27_HUMAN
θ value	3.0926 (rank : 139)	NC score	0.051358 (rank : 126)
Query Neighborhood Hits	217	Target Neighborhood Hits	39	Shared Neighborhood Hits	22
SwissProt Accessions	Q8NI29, Q96C87	Gene names	FBXO27, FBG5, FBX27
Domain Architecture
Description	F-box only protein 27 (F-box/G-domain protein 5).

K1045_HUMAN
θ value	3.0926 (rank : 140)	NC score	0.041483 (rank : 144)
Query Neighborhood Hits	217	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UPV7, Q58FE9, Q5T662	Gene names	KIAA1045
Domain Architecture	No domain graphic available
Description	Protein KIAA1045.

NEDD4_MOUSE
θ value	3.0926 (rank : 141)	NC score	0.007840 (rank : 231)
Query Neighborhood Hits	217	Target Neighborhood Hits	212	Shared Neighborhood Hits	4
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

OGFR_HUMAN
θ value	3.0926 (rank : 142)	NC score	0.069770 (rank : 80)
Query Neighborhood Hits	217	Target Neighborhood Hits	1582	Shared Neighborhood Hits	115
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

PF21A_MOUSE
θ value	3.0926 (rank : 143)	NC score	0.044374 (rank : 135)
Query Neighborhood Hits	217	Target Neighborhood Hits	285	Shared Neighborhood Hits	26
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

PRRT1_MOUSE
θ value	3.0926 (rank : 144)	NC score	0.032985 (rank : 170)
Query Neighborhood Hits	217	Target Neighborhood Hits	102	Shared Neighborhood Hits	14
SwissProt Accessions	O35449	Gene names	Prrt1, Ng5
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 1.

WASF2_MOUSE
θ value	3.0926 (rank : 145)	NC score	0.031377 (rank : 176)
Query Neighborhood Hits	217	Target Neighborhood Hits	315	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

BAT2_MOUSE
θ value	4.03905 (rank : 146)	NC score	0.056604 (rank : 108)
Query Neighborhood Hits	217	Target Neighborhood Hits	947	Shared Neighborhood Hits	89
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

FBX16_MOUSE
θ value	4.03905 (rank : 147)	NC score	0.104961 (rank : 56)
Query Neighborhood Hits	217	Target Neighborhood Hits	39	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QZM9, Q3TP74, Q8C5V6	Gene names	Fbxo16, Fbx16
Domain Architecture
Description	F-box only protein 16.

FBX39_MOUSE
θ value	4.03905 (rank : 148)	NC score	0.076374 (rank : 68)
Query Neighborhood Hits	217	Target Neighborhood Hits	34	Shared Neighborhood Hits	23
SwissProt Accessions	Q5NBU5	Gene names	Fbxo39
Domain Architecture	No domain graphic available
Description	F-box only protein 39.

PRR12_HUMAN
θ value	4.03905 (rank : 149)	NC score	0.054854 (rank : 117)
Query Neighborhood Hits	217	Target Neighborhood Hits	460	Shared Neighborhood Hits	41
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

SF3A2_HUMAN
θ value	4.03905 (rank : 150)	NC score	0.038282 (rank : 153)
Query Neighborhood Hits	217	Target Neighborhood Hits	263	Shared Neighborhood Hits	22
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

TRI66_MOUSE
θ value	4.03905 (rank : 151)	NC score	0.034692 (rank : 163)
Query Neighborhood Hits	217	Target Neighborhood Hits	491	Shared Neighborhood Hits	43
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

WASIP_HUMAN
θ value	4.03905 (rank : 152)	NC score	0.059230 (rank : 104)
Query Neighborhood Hits	217	Target Neighborhood Hits	458	Shared Neighborhood Hits	44
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

ALMS1_MOUSE
θ value	5.27518 (rank : 153)	NC score	0.020030 (rank : 207)
Query Neighborhood Hits	217	Target Neighborhood Hits	181	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K4E0, Q6A084, Q8C9N9	Gene names	Alms1, Kiaa0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1 homolog.

ATX2_HUMAN
θ value	5.27518 (rank : 154)	NC score	0.023479 (rank : 200)
Query Neighborhood Hits	217	Target Neighborhood Hits	375	Shared Neighborhood Hits	31
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

CIC_HUMAN
θ value	5.27518 (rank : 155)	NC score	0.046969 (rank : 130)
Query Neighborhood Hits	217	Target Neighborhood Hits	992	Shared Neighborhood Hits	102
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CIC_MOUSE
θ value	5.27518 (rank : 156)	NC score	0.031446 (rank : 175)
Query Neighborhood Hits	217	Target Neighborhood Hits	742	Shared Neighborhood Hits	61
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

DAG1_HUMAN
θ value	5.27518 (rank : 157)	NC score	0.016120 (rank : 216)
Query Neighborhood Hits	217	Target Neighborhood Hits	104	Shared Neighborhood Hits	13
SwissProt Accessions	Q14118	Gene names	DAG1
Domain Architecture
Description	Dystroglycan precursor (Dystrophin-associated glycoprotein 1) [Contains: Alpha-dystroglycan (Alpha-DG); Beta-dystroglycan (Beta- DG)].

FBLI1_HUMAN
θ value	5.27518 (rank : 158)	NC score	0.021737 (rank : 203)
Query Neighborhood Hits	217	Target Neighborhood Hits	200	Shared Neighborhood Hits	14
SwissProt Accessions	Q8WUP2, Q5VVE0, Q5VVE1, Q8IX23, Q96T00, Q9UFD6	Gene names	FBLIM1, FBLP1
Domain Architecture
Description	Filamin-binding LIM protein 1 (Filamin-binding LIM protein 1) (FBLP-1) (Mitogen-inducible 2-interacting protein) (MIG2-interacting protein) (Migfilin).

FBXW7_HUMAN
θ value	5.27518 (rank : 159)	NC score	0.036120 (rank : 159)
Query Neighborhood Hits	217	Target Neighborhood Hits	433	Shared Neighborhood Hits	38
SwissProt Accessions	Q969H0, Q96A16, Q96LE0, Q96RI2, Q9NUX6	Gene names	FBXW7, FBW7, FBX30, SEL10
Domain Architecture
Description	F-box/WD repeat protein 7 (F-box and WD-40 domain protein 7) (F-box protein FBX30) (hCdc4) (Archipelago homolog) (hAgo) (SEL-10).

FBXW7_MOUSE
θ value	5.27518 (rank : 160)	NC score	0.034790 (rank : 162)
Query Neighborhood Hits	217	Target Neighborhood Hits	365	Shared Neighborhood Hits	34
SwissProt Accessions	Q8VBV4, Q8CCS5, Q8VHP4	Gene names	Fbxw7, Fbw7, Fbwd6, Fbxw6
Domain Architecture
Description	F-box/WD repeat protein 7 (F-box and WD-40 domain protein 7) (F-box protein FBW7) (F-box protein Fbxw6) (F-box-WD40 repeat protein 6) (SEL-10).

GA2L3_HUMAN
θ value	5.27518 (rank : 161)	NC score	0.019769 (rank : 210)
Query Neighborhood Hits	217	Target Neighborhood Hits	189	Shared Neighborhood Hits	14
SwissProt Accessions	Q86XJ1	Gene names	GAS2L3
Domain Architecture	No domain graphic available
Description	GAS2-like protein 3 (Growth arrest-specific 2-like 3).

LAP4_MOUSE
θ value	5.27518 (rank : 162)	NC score	0.002338 (rank : 246)
Query Neighborhood Hits	217	Target Neighborhood Hits	590	Shared Neighborhood Hits	15
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

M3K10_HUMAN
θ value	5.27518 (rank : 163)	NC score	-0.000196 (rank : 247)
Query Neighborhood Hits	217	Target Neighborhood Hits	1071	Shared Neighborhood Hits	15
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

MYCB2_MOUSE
θ value	5.27518 (rank : 164)	NC score	0.015477 (rank : 217)
Query Neighborhood Hits	217	Target Neighborhood Hits	307	Shared Neighborhood Hits	12
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

PHF22_MOUSE
θ value	5.27518 (rank : 165)	NC score	0.056014 (rank : 110)
Query Neighborhood Hits	217	Target Neighborhood Hits	89	Shared Neighborhood Hits	14
SwissProt Accessions	Q9D168, Q3U2Q5, Q921U2	Gene names	Ints12, Phf22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

PRRT3_MOUSE
θ value	5.27518 (rank : 166)	NC score	0.052795 (rank : 123)
Query Neighborhood Hits	217	Target Neighborhood Hits	162	Shared Neighborhood Hits	21
SwissProt Accessions	Q6PE13	Gene names	Prrt3
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

RXRB_MOUSE
θ value	5.27518 (rank : 167)	NC score	0.005474 (rank : 240)
Query Neighborhood Hits	217	Target Neighborhood Hits	230	Shared Neighborhood Hits	19
SwissProt Accessions	P28704, P33243	Gene names	Rxrb, Nr2b2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta) (MHC class I regulatory element-binding protein H-2RIIBP).

SF3A2_MOUSE
θ value	5.27518 (rank : 168)	NC score	0.037298 (rank : 156)
Query Neighborhood Hits	217	Target Neighborhood Hits	247	Shared Neighborhood Hits	27
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

ULK1_HUMAN
θ value	5.27518 (rank : 169)	NC score	0.003343 (rank : 243)
Query Neighborhood Hits	217	Target Neighborhood Hits	1121	Shared Neighborhood Hits	42
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).

WASF1_MOUSE
θ value	5.27518 (rank : 170)	NC score	0.024456 (rank : 197)
Query Neighborhood Hits	217	Target Neighborhood Hits	261	Shared Neighborhood Hits	25
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

XYLT1_HUMAN
θ value	5.27518 (rank : 171)	NC score	0.011261 (rank : 228)
Query Neighborhood Hits	217	Target Neighborhood Hits	87	Shared Neighborhood Hits	8
SwissProt Accessions	Q86Y38, Q9H1B6	Gene names	XYLT1, XT1
Domain Architecture	No domain graphic available
Description	Xylosyltransferase 1 (EC 2.4.2.26) (Xylosyltransferase I) (XylT-I) (XT-I) (Peptide O-xylosyltransferase 1).

YLPM1_MOUSE
θ value	5.27518 (rank : 172)	NC score	0.043388 (rank : 139)
Query Neighborhood Hits	217	Target Neighborhood Hits	505	Shared Neighborhood Hits	33
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

ATN1_HUMAN
θ value	6.88961 (rank : 173)	NC score	0.036365 (rank : 158)
Query Neighborhood Hits	217	Target Neighborhood Hits	676	Shared Neighborhood Hits	50
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

FMN1A_MOUSE
θ value	6.88961 (rank : 174)	NC score	0.032379 (rank : 173)
Query Neighborhood Hits	217	Target Neighborhood Hits	423	Shared Neighborhood Hits	34
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

FMN1B_MOUSE
θ value	6.88961 (rank : 175)	NC score	0.033165 (rank : 169)
Query Neighborhood Hits	217	Target Neighborhood Hits	447	Shared Neighborhood Hits	36
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

FMNL_HUMAN
θ value	6.88961 (rank : 176)	NC score	0.035541 (rank : 160)
Query Neighborhood Hits	217	Target Neighborhood Hits	529	Shared Neighborhood Hits	40
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

FXL21_HUMAN
θ value	6.88961 (rank : 177)	NC score	0.071166 (rank : 76)
Query Neighborhood Hits	217	Target Neighborhood Hits	43	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UKT6	Gene names	FBXL21, FBL21, FBL3, FBXL3B
Domain Architecture
Description	F-box/LRR-repeat protein 21 (F-box and leucine-rich repeat protein 21) (F-box/LRR-repeat protein 3B) (F-box and leucine-rich repeat protein 3B).

HXB4_HUMAN
θ value	6.88961 (rank : 178)	NC score	0.005720 (rank : 239)
Query Neighborhood Hits	217	Target Neighborhood Hits	376	Shared Neighborhood Hits	16
SwissProt Accessions	P17483, Q9NTA0	Gene names	HOXB4, HOX2F
Domain Architecture
Description	Homeobox protein Hox-B4 (Hox-2F) (Hox-2.6).

HXB4_MOUSE
θ value	6.88961 (rank : 179)	NC score	0.003181 (rank : 244)
Query Neighborhood Hits	217	Target Neighborhood Hits	375	Shared Neighborhood Hits	13
SwissProt Accessions	P10284, Q3UZB4, Q4VBG0	Gene names	Hoxb4, Hox-2.6, Hoxb-4
Domain Architecture
Description	Homeobox protein Hox-B4 (Hox-2.6).

MBB1A_HUMAN
θ value	6.88961 (rank : 180)	NC score	0.038611 (rank : 152)
Query Neighborhood Hits	217	Target Neighborhood Hits	665	Shared Neighborhood Hits	62
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

PDE3A_HUMAN
θ value	6.88961 (rank : 181)	NC score	0.007494 (rank : 232)
Query Neighborhood Hits	217	Target Neighborhood Hits	79	Shared Neighborhood Hits	4
SwissProt Accessions	Q14432, O60865, Q13348	Gene names	PDE3A
Domain Architecture
Description	cGMP-inhibited 3',5'-cyclic phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A).

PDE3A_MOUSE
θ value	6.88961 (rank : 182)	NC score	0.011718 (rank : 225)
Query Neighborhood Hits	217	Target Neighborhood Hits	115	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z0X4	Gene names	Pde3a
Domain Architecture
Description	cGMP-inhibited 3',5'-cyclic phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A).

PF21A_HUMAN
θ value	6.88961 (rank : 183)	NC score	0.038894 (rank : 151)
Query Neighborhood Hits	217	Target Neighborhood Hits	303	Shared Neighborhood Hits	28
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

POLH_MOUSE
θ value	6.88961 (rank : 184)	NC score	0.009555 (rank : 230)
Query Neighborhood Hits	217	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JJN0, Q9JJJ2	Gene names	Polh, Rad30a, Xpv
Domain Architecture	No domain graphic available
Description	DNA polymerase eta (EC 2.7.7.7) (RAD30 homolog A) (Xeroderma pigmentosum variant type protein homolog).

RFIP1_MOUSE
θ value	6.88961 (rank : 185)	NC score	0.013231 (rank : 220)
Query Neighborhood Hits	217	Target Neighborhood Hits	152	Shared Neighborhood Hits	10
SwissProt Accessions	Q9D620, Q3UBC2, Q8BN24	Gene names	Rab11fip1, Rcp
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

SF01_HUMAN
θ value	6.88961 (rank : 186)	NC score	0.030703 (rank : 179)
Query Neighborhood Hits	217	Target Neighborhood Hits	287	Shared Neighborhood Hits	30
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

SF01_MOUSE
θ value	6.88961 (rank : 187)	NC score	0.030494 (rank : 180)
Query Neighborhood Hits	217	Target Neighborhood Hits	240	Shared Neighborhood Hits	28
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

SF3B4_HUMAN
θ value	6.88961 (rank : 188)	NC score	0.013007 (rank : 221)
Query Neighborhood Hits	217	Target Neighborhood Hits	445	Shared Neighborhood Hits	28
SwissProt Accessions	Q15427	Gene names	SF3B4, SAP49
Domain Architecture
Description	Splicing factor 3B subunit 4 (Spliceosome-associated protein 49) (SAP 49) (SF3b50) (Pre-mRNA-splicing factor SF3b 49 kDa subunit).

SRRM1_HUMAN
θ value	6.88961 (rank : 189)	NC score	0.057839 (rank : 106)
Query Neighborhood Hits	217	Target Neighborhood Hits	690	Shared Neighborhood Hits	58
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

CF182_MOUSE
θ value	8.99809 (rank : 190)	NC score	0.006770 (rank : 236)
Query Neighborhood Hits	217	Target Neighborhood Hits	551	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VDS7, Q9CZE0, Q9D5A1	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf182 homolog.

EGLN2_HUMAN
θ value	8.99809 (rank : 191)	NC score	0.007058 (rank : 234)
Query Neighborhood Hits	217	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q96KS0, Q8WWY4, Q9BV14	Gene names	EGLN2, EIT6
Domain Architecture
Description	Egl nine homolog 2 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 1) (HIF-prolyl hydroxylase 1) (HIF-PH1) (HPH-3) (Prolyl hydroxylase domain-containing protein 1) (PHD1) (Estrogen-induced tag 6).

ENAH_HUMAN
θ value	8.99809 (rank : 192)	NC score	0.023602 (rank : 198)
Query Neighborhood Hits	217	Target Neighborhood Hits	784	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

FBXW5_HUMAN
θ value	8.99809 (rank : 193)	NC score	0.027890 (rank : 189)
Query Neighborhood Hits	217	Target Neighborhood Hits	156	Shared Neighborhood Hits	21
SwissProt Accessions	Q969U6, Q5SPZ8, Q5SPZ9, Q5SQ02, Q5SQ03, Q5SQ04, Q8WY79, Q96GJ6, Q9BSU8, Q9H6A8, Q9HBQ6, Q9NSZ3	Gene names	FBXW5, FBW5
Domain Architecture
Description	F-box/WD repeat protein 5 (F-box and WD-40 domain protein 5).

FBXW5_MOUSE
θ value	8.99809 (rank : 194)	NC score	0.028443 (rank : 186)
Query Neighborhood Hits	217	Target Neighborhood Hits	159	Shared Neighborhood Hits	22
SwissProt Accessions	Q9QXW2	Gene names	Fbxw5, Fbw5
Domain Architecture
Description	F-box/WD repeat protein 5 (F-box and WD-40 domain protein 5).

FHOD1_MOUSE
θ value	8.99809 (rank : 195)	NC score	0.025990 (rank : 192)
Query Neighborhood Hits	217	Target Neighborhood Hits	217	Shared Neighborhood Hits	28
SwissProt Accessions	Q6P9Q4, Q8BMK2	Gene names	Fhod1, Fhos1
Domain Architecture	No domain graphic available
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

GP178_HUMAN
θ value	8.99809 (rank : 196)	NC score	0.016490 (rank : 214)
Query Neighborhood Hits	217	Target Neighborhood Hits	25	Shared Neighborhood Hits	6
SwissProt Accessions	Q9P2C4, Q5VTU1	Gene names	GPR178, KIAA1423
Domain Architecture	No domain graphic available
Description	Integral membrane protein GPR178.

HES7_MOUSE
θ value	8.99809 (rank : 197)	NC score	0.016489 (rank : 215)
Query Neighborhood Hits	217	Target Neighborhood Hits	72	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BKT2, Q99JA6	Gene names	Hes7
Domain Architecture	No domain graphic available
Description	Transcription factor HES-7 (Hairy and enhancer of split 7) (bHLH factor Hes7).

JAD1A_HUMAN
θ value	8.99809 (rank : 198)	NC score	0.040393 (rank : 148)
Query Neighborhood Hits	217	Target Neighborhood Hits	328	Shared Neighborhood Hits	28
SwissProt Accessions	P29375	Gene names	JARID1A, RBBP2, RBP2
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1A (Retinoblastoma-binding protein 2) (RBBP-2).

K0562_MOUSE
θ value	8.99809 (rank : 199)	NC score	0.011569 (rank : 226)
Query Neighborhood Hits	217	Target Neighborhood Hits	86	Shared Neighborhood Hits	8
SwissProt Accessions	Q80V31, Q6ZQ95	Gene names	Kiaa0562
Domain Architecture	No domain graphic available
Description	Protein KIAA0562.

K1045_MOUSE
θ value	8.99809 (rank : 200)	NC score	0.027929 (rank : 188)
Query Neighborhood Hits	217	Target Neighborhood Hits	15	Shared Neighborhood Hits	5
SwissProt Accessions	Q80TL4, Q8BH08	Gene names	Kiaa1045
Domain Architecture	No domain graphic available
Description	Protein KIAA1045.

KCNC3_HUMAN
θ value	8.99809 (rank : 201)	NC score	0.007311 (rank : 233)
Query Neighborhood Hits	217	Target Neighborhood Hits	256	Shared Neighborhood Hits	29
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

LTBP4_MOUSE
θ value	8.99809 (rank : 202)	NC score	0.004676 (rank : 241)
Query Neighborhood Hits	217	Target Neighborhood Hits	607	Shared Neighborhood Hits	28
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

MLL2_HUMAN
θ value	8.99809 (rank : 203)	NC score	0.080161 (rank : 62)
Query Neighborhood Hits	217	Target Neighborhood Hits	1788	Shared Neighborhood Hits	110
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MYST4_HUMAN
θ value	8.99809 (rank : 204)	NC score	0.066813 (rank : 85)
Query Neighborhood Hits	217	Target Neighborhood Hits	671	Shared Neighborhood Hits	48
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

NFAC1_HUMAN
θ value	8.99809 (rank : 205)	NC score	0.017485 (rank : 212)
Query Neighborhood Hits	217	Target Neighborhood Hits	312	Shared Neighborhood Hits	44
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

PDZD2_HUMAN
θ value	8.99809 (rank : 206)	NC score	0.020008 (rank : 208)
Query Neighborhood Hits	217	Target Neighborhood Hits	772	Shared Neighborhood Hits	45
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

PRP2_MOUSE
θ value	8.99809 (rank : 207)	NC score	0.046880 (rank : 131)
Query Neighborhood Hits	217	Target Neighborhood Hits	347	Shared Neighborhood Hits	36
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PSL1_HUMAN
θ value	8.99809 (rank : 208)	NC score	0.044731 (rank : 134)
Query Neighborhood Hits	217	Target Neighborhood Hits	650	Shared Neighborhood Hits	86
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

RYR1_HUMAN
θ value	8.99809 (rank : 209)	NC score	0.012636 (rank : 222)
Query Neighborhood Hits	217	Target Neighborhood Hits	303	Shared Neighborhood Hits	16
SwissProt Accessions	P21817, Q16314, Q16368, Q9NPK1, Q9P1U4	Gene names	RYR1, RYDR
Domain Architecture
Description	Ryanodine receptor 1 (Skeletal muscle-type ryanodine receptor) (RyR1) (RYR-1) (Skeletal muscle calcium release channel).

SFPQ_HUMAN
θ value	8.99809 (rank : 210)	NC score	0.025696 (rank : 193)
Query Neighborhood Hits	217	Target Neighborhood Hits	986	Shared Neighborhood Hits	54
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

SREC2_HUMAN
θ value	8.99809 (rank : 211)	NC score	0.004334 (rank : 242)
Query Neighborhood Hits	217	Target Neighborhood Hits	645	Shared Neighborhood Hits	25
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

TACC2_MOUSE
θ value	8.99809 (rank : 212)	NC score	0.026077 (rank : 191)
Query Neighborhood Hits	217	Target Neighborhood Hits	774	Shared Neighborhood Hits	35
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

TS13_MOUSE
θ value	8.99809 (rank : 213)	NC score	0.030359 (rank : 181)
Query Neighborhood Hits	217	Target Neighborhood Hits	191	Shared Neighborhood Hits	22
SwissProt Accessions	Q01755	Gene names	Tcp11
Domain Architecture
Description	Testis-specific protein PBS13.

VINC_HUMAN
θ value	8.99809 (rank : 214)	NC score	0.012495 (rank : 223)
Query Neighborhood Hits	217	Target Neighborhood Hits	145	Shared Neighborhood Hits	9
SwissProt Accessions	P18206, Q16450, Q5SWX2, Q7Z3B8, Q8IXU7	Gene names	VCL
Domain Architecture
Description	Vinculin (Metavinculin).

VINC_MOUSE
θ value	8.99809 (rank : 215)	NC score	0.011265 (rank : 227)
Query Neighborhood Hits	217	Target Neighborhood Hits	135	Shared Neighborhood Hits	9
SwissProt Accessions	Q64727, Q8BP32, Q8BS46, Q922C5, Q922D9	Gene names	Vcl
Domain Architecture
Description	Vinculin (Metavinculin).

ZCHC3_HUMAN
θ value	8.99809 (rank : 216)	NC score	0.014896 (rank : 218)
Query Neighborhood Hits	217	Target Neighborhood Hits	53	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NUD5, Q6NT79	Gene names	ZCCHC3, C20orf99
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 3.

ZN750_MOUSE
θ value	8.99809 (rank : 217)	NC score	0.030759 (rank : 178)
Query Neighborhood Hits	217	Target Neighborhood Hits	346	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

BAZ1B_HUMAN
θ value	θ > 10 (rank : 218)	NC score	0.052607 (rank : 124)
Query Neighborhood Hits	217	Target Neighborhood Hits	701	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

CD2_HUMAN
θ value	θ > 10 (rank : 219)	NC score	0.052143 (rank : 125)
Query Neighborhood Hits	217	Target Neighborhood Hits	504	Shared Neighborhood Hits	81
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

DIDO1_HUMAN
θ value	θ > 10 (rank : 220)	NC score	0.054574 (rank : 119)
Query Neighborhood Hits	217	Target Neighborhood Hits	960	Shared Neighborhood Hits	91
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

FA47A_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.053997 (rank : 120)
Query Neighborhood Hits	217	Target Neighborhood Hits	451	Shared Neighborhood Hits	66
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

FBW12_HUMAN
θ value	θ > 10 (rank : 222)	NC score	0.070911 (rank : 77)
Query Neighborhood Hits	217	Target Neighborhood Hits	60	Shared Neighborhood Hits	23
SwissProt Accessions	Q6X9E4	Gene names	FBXW12, FBW12, FBXO12, FBXO35
Domain Architecture	No domain graphic available
Description	F-box/WD repeat protein 12 (F-box and WD-40 domain protein 12) (F-box only protein 35).

FBX33_HUMAN
θ value	θ > 10 (rank : 223)	NC score	0.063255 (rank : 92)
Query Neighborhood Hits	217	Target Neighborhood Hits	42	Shared Neighborhood Hits	23
SwissProt Accessions	Q7Z6M2, Q6PIR2, Q86TR2, Q86YE0	Gene names	FBXO33, FBX33
Domain Architecture	No domain graphic available
Description	F-box only protein 33.

FBX36_HUMAN
θ value	θ > 10 (rank : 224)	NC score	0.054728 (rank : 118)
Query Neighborhood Hits	217	Target Neighborhood Hits	30	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NEA4, Q8WWD4	Gene names	FBXO36, FBX36
Domain Architecture	No domain graphic available
Description	F-box only protein 36.

FBX41_MOUSE
θ value	θ > 10 (rank : 225)	NC score	0.078173 (rank : 65)
Query Neighborhood Hits	217	Target Neighborhood Hits	430	Shared Neighborhood Hits	28
SwissProt Accessions	Q6NS60, Q6P7W4, Q6ZPG1	Gene names	Fbxo41, D6Ertd538e, Kiaa1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

FBXL3_HUMAN
θ value	θ > 10 (rank : 226)	NC score	0.079948 (rank : 63)
Query Neighborhood Hits	217	Target Neighborhood Hits	36	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UKT7, Q9P122	Gene names	FBXL3, FBL3A, FBXL3A
Domain Architecture
Description	F-box/LRR-repeat protein 3 (F-box/LRR-repeat protein 3A) (F-box and leucine-rich repeat protein 3A).

FBXL3_MOUSE
θ value	θ > 10 (rank : 227)	NC score	0.077257 (rank : 66)
Query Neighborhood Hits	217	Target Neighborhood Hits	37	Shared Neighborhood Hits	25
SwissProt Accessions	Q8C4V4, Q80V32, Q8K1W0, Q9QXW1	Gene names	Fbxl3, Fbl3a, Fbxl3a
Domain Architecture
Description	F-box/LRR-repeat protein 3 (F-box/LRR-repeat protein 3A) (F-box and leucine-rich repeat protein 3A).

FXL21_MOUSE
θ value	θ > 10 (rank : 228)	NC score	0.094562 (rank : 60)
Query Neighborhood Hits	217	Target Neighborhood Hits	49	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BFZ4, Q8BIJ8, Q8BIW5	Gene names	Fbxl21, Fbl21, Fbxl3b
Domain Architecture
Description	F-box/LRR-repeat protein 21 (F-box and leucine-rich repeat protein 21) (F-box/LRR-repeat protein 3B) (F-box and leucine-rich repeat protein 3B).

K1718_HUMAN
θ value	θ > 10 (rank : 229)	NC score	0.280534 (rank : 35)
Query Neighborhood Hits	217	Target Neighborhood Hits	114	Shared Neighborhood Hits	10
SwissProt Accessions	Q6ZMT4, Q6MZL8, Q9C0E5	Gene names	KIAA1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

K1718_MOUSE
θ value	θ > 10 (rank : 230)	NC score	0.283444 (rank : 34)
Query Neighborhood Hits	217	Target Neighborhood Hits	98	Shared Neighborhood Hits	12
SwissProt Accessions	Q3UWM4, Q3UWN8, Q6ZPJ5, Q8C969, Q8C9E0, Q91VX8	Gene names	Kiaa1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

LCP2_HUMAN
θ value	θ > 10 (rank : 231)	NC score	0.057211 (rank : 107)
Query Neighborhood Hits	217	Target Neighborhood Hits	531	Shared Neighborhood Hits	71
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

MDC1_HUMAN
θ value	θ > 10 (rank : 232)	NC score	0.050701 (rank : 128)
Query Neighborhood Hits	217	Target Neighborhood Hits	1446	Shared Neighborhood Hits	97
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MYST4_MOUSE
θ value	θ > 10 (rank : 233)	NC score	0.066287 (rank : 88)
Query Neighborhood Hits	217	Target Neighborhood Hits	416	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

NACAM_MOUSE
θ value	θ > 10 (rank : 234)	NC score	0.055371 (rank : 115)
Query Neighborhood Hits	217	Target Neighborhood Hits	1866	Shared Neighborhood Hits	122
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NCOA6_HUMAN
θ value	θ > 10 (rank : 235)	NC score	0.051193 (rank : 127)
Query Neighborhood Hits	217	Target Neighborhood Hits	1202	Shared Neighborhood Hits	102
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

PHF2_HUMAN
θ value	θ > 10 (rank : 236)	NC score	0.271721 (rank : 37)
Query Neighborhood Hits	217	Target Neighborhood Hits	208	Shared Neighborhood Hits	19
SwissProt Accessions	O75151, Q8N3K2, Q9Y6N4	Gene names	PHF2, KIAA0662
Domain Architecture
Description	PHD finger protein 2 (GRC5).

PHF2_MOUSE
θ value	θ > 10 (rank : 237)	NC score	0.273059 (rank : 36)
Query Neighborhood Hits	217	Target Neighborhood Hits	241	Shared Neighborhood Hits	22
SwissProt Accessions	Q9WTU0, Q80WA8	Gene names	Phf2
Domain Architecture
Description	PHD finger protein 2 (GRC5).

PHF8_HUMAN
θ value	θ > 10 (rank : 238)	NC score	0.287052 (rank : 33)
Query Neighborhood Hits	217	Target Neighborhood Hits	105	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UPP1, Q5H9U5, Q5VUJ4, Q7Z6D4, Q9HAH2	Gene names	PHF8, KIAA1111, ZNF422
Domain Architecture	No domain graphic available
Description	PHD finger protein 8.

PHF8_MOUSE
θ value	θ > 10 (rank : 239)	NC score	0.287180 (rank : 32)
Query Neighborhood Hits	217	Target Neighborhood Hits	96	Shared Neighborhood Hits	14
SwissProt Accessions	Q80TJ7, Q8BLX8, Q8BLY0, Q8BZ61, Q8CG26	Gene names	Phf8, Kiaa1111
Domain Architecture	No domain graphic available
Description	PHD finger protein 8.

PTDSR_HUMAN
θ value	θ > 10 (rank : 240)	NC score	0.061976 (rank : 93)
Query Neighborhood Hits	217	Target Neighborhood Hits	22	Shared Neighborhood Hits	5
SwissProt Accessions	Q6NYC1, Q86VY0, Q8IUM5, Q9Y4E2	Gene names	PTDSR, KIAA0585
Domain Architecture	No domain graphic available
Description	Protein PTDSR (Phosphatidylserine receptor).

PTDSR_MOUSE
θ value	θ > 10 (rank : 241)	NC score	0.061901 (rank : 94)
Query Neighborhood Hits	217	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ERI5, Q80TX1	Gene names	Ptdsr, Kiaa0585
Domain Architecture	No domain graphic available
Description	Protein PTDSR (Phosphatidylserine receptor) (Apoptotic cell clearance receptor PtdSerR).

SET1A_HUMAN
θ value	θ > 10 (rank : 242)	NC score	0.073443 (rank : 72)
Query Neighborhood Hits	217	Target Neighborhood Hits	690	Shared Neighborhood Hits	50
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SETD8_HUMAN
θ value	θ > 10 (rank : 243)	NC score	0.060235 (rank : 100)
Query Neighborhood Hits	217	Target Neighborhood Hits	114	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NQR1, Q86W83, Q8TD09	Gene names	SETD8, PRSET7, SET07, SET8
Domain Architecture
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8) (PR/SET domain-containing protein 07) (PR/SET07) (PR-Set7).

SRRM1_MOUSE
θ value	θ > 10 (rank : 244)	NC score	0.065750 (rank : 89)
Query Neighborhood Hits	217	Target Neighborhood Hits	966	Shared Neighborhood Hits	79
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

VCX1_HUMAN
θ value	θ > 10 (rank : 245)	NC score	0.053168 (rank : 122)
Query Neighborhood Hits	217	Target Neighborhood Hits	129	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H320, Q9P0H3	Gene names	VCX, VCX1, VCX10R, VCXB1
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 1 (VCX-B1 protein) (Variably charged protein X-B1) (Variable charge protein on X with ten repeats) (VCX- 10r).

VCX3_HUMAN
θ value	θ > 10 (rank : 246)	NC score	0.060880 (rank : 97)
Query Neighborhood Hits	217	Target Neighborhood Hits	105	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NNX9, Q9P0H4	Gene names	VCX3A, VCX3, VCX8R, VCXA
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 3 (VCX-A protein) (Variably charged protein X-A) (Variable charge protein on X with eight repeats) (VCX- 8r).

VCXC_HUMAN
θ value	θ > 10 (rank : 247)	NC score	0.060044 (rank : 101)
Query Neighborhood Hits	217	Target Neighborhood Hits	139	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H321	Gene names	VCXC
Domain Architecture	No domain graphic available
Description	VCX-C protein (Variably charged protein X-C).

Hits sorted by NC score

FXL19_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	217	Target Neighborhood Hits	217	Shared Neighborhood Hits	217
SwissProt Accessions	Q6PB97, Q7TSH0, Q8BIB4	Gene names	Fbxl19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

FXL19_HUMAN
NC score	0.983322 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	217	Target Neighborhood Hits	147	Shared Neighborhood Hits	116
SwissProt Accessions	Q6PCT2, Q8N789, Q9NT14	Gene names	FBXL19, FBL19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

JHD1B_HUMAN
NC score	0.766350 (rank : 3)	θ value	1.70789e-91 (rank : 4)
Query Neighborhood Hits	217	Target Neighborhood Hits	178	Shared Neighborhood Hits	59
SwissProt Accessions	Q8NHM5, Q8NCI2, Q96HC7, Q96SL0, Q96T03, Q9NS96, Q9UF75	Gene names	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (Protein JEMMA) (Jumonji domain-containing EMSY-interactor methyltransferase motif protein) (CXXC-type zinc finger protein 2) (Protein-containing CXXC domain 2).

JHD1B_MOUSE
NC score	0.763533 (rank : 4)	θ value	7.66637e-92 (rank : 3)
Query Neighborhood Hits	217	Target Neighborhood Hits	214	Shared Neighborhood Hits	63
SwissProt Accessions	Q6P1G2, Q3V396, Q6PFD0, Q6ZPE8, Q9CSF7, Q9QZN6	Gene names	Fbxl10, Fbl10, Jhdm1b, Kiaa3014
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10).

JHD1A_HUMAN
NC score	0.748375 (rank : 5)	θ value	1.11217e-74 (rank : 5)
Query Neighborhood Hits	217	Target Neighborhood Hits	133	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y2K7, Q49A21, Q4G0M3, Q69YY8, Q9BVH5, Q9H7H5, Q9UK66	Gene names	FBXL11, FBL7, JHDM1A, KIAA1004
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina).

JHD1A_MOUSE
NC score	0.746770 (rank : 6)	θ value	2.47765e-74 (rank : 6)
Query Neighborhood Hits	217	Target Neighborhood Hits	134	Shared Neighborhood Hits	52
SwissProt Accessions	P59997, Q3U1M5, Q3UR56, Q3V3Q1, Q69ZT4	Gene names	Fbxl11, Jhdm1a, Kiaa1004
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11).

FBXL7_HUMAN
NC score	0.564583 (rank : 7)	θ value	1.133e-10 (rank : 9)
Query Neighborhood Hits	217	Target Neighborhood Hits	91	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UJT9, O94926	Gene names	FBXL7, FBL6, FBL7, KIAA0840
Domain Architecture
Description	F-box/LRR-repeat protein 7 (F-box and leucine-rich repeat protein 7) (F-box protein FBL6/FBL7).

FXL20_HUMAN
NC score	0.543216 (rank : 8)	θ value	1.33837e-11 (rank : 8)
Query Neighborhood Hits	217	Target Neighborhood Hits	77	Shared Neighborhood Hits	42
SwissProt Accessions	Q96IG2	Gene names	FBXL20, FBL2
Domain Architecture
Description	F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like).

FXL20_MOUSE
NC score	0.542843 (rank : 9)	θ value	1.02475e-11 (rank : 7)
Query Neighborhood Hits	217	Target Neighborhood Hits	78	Shared Neighborhood Hits	42
SwissProt Accessions	Q9CZV8, Q8BZ95	Gene names	Fbxl20, Fbl2
Domain Architecture
Description	F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like).

FBXL2_MOUSE
NC score	0.528571 (rank : 10)	θ value	2.52405e-10 (rank : 10)
Query Neighborhood Hits	217	Target Neighborhood Hits	83	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BH16, Q8BXM4	Gene names	Fbxl2, Fbl2
Domain Architecture
Description	F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2).

FXL14_MOUSE
NC score	0.524698 (rank : 11)	θ value	3.29651e-10 (rank : 12)
Query Neighborhood Hits	217	Target Neighborhood Hits	72	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BID8, Q3U2Q9, Q8R5H7, Q8VDT7, Q922N5	Gene names	Fbxl14, Fbl14, Ppa
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 14 (F-box and leucine-rich repeat protein 14).

FXL14_HUMAN
NC score	0.523813 (rank : 12)	θ value	3.29651e-10 (rank : 11)
Query Neighborhood Hits	217	Target Neighborhood Hits	71	Shared Neighborhood Hits	40
SwissProt Accessions	Q8N1E6	Gene names	FBXL14, FBL14
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 14 (F-box and leucine-rich repeat protein 14).

FBXL2_HUMAN
NC score	0.520039 (rank : 13)	θ value	2.79066e-09 (rank : 13)
Query Neighborhood Hits	217	Target Neighborhood Hits	77	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UKC9, Q9NVQ8, Q9UK27, Q9UKA5, Q9Y3Y9	Gene names	FBXL2, FBL2, FBL3
Domain Architecture
Description	F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2) (F-box protein FBL2/FBL3).

LRC29_HUMAN
NC score	0.517672 (rank : 14)	θ value	2.44474e-05 (rank : 27)
Query Neighborhood Hits	217	Target Neighborhood Hits	37	Shared Neighborhood Hits	28
SwissProt Accessions	Q8WV35, Q9UKA0	Gene names	LRRC29, FBL9, FBXL9
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 29 (F-box/LRR-repeat protein 9) (F-box and leucine-rich repeat protein 9) (F-box protein FBL9).

FXL16_HUMAN
NC score	0.510596 (rank : 15)	θ value	8.40245e-06 (rank : 26)
Query Neighborhood Hits	217	Target Neighborhood Hits	85	Shared Neighborhood Hits	33
SwissProt Accessions	Q8N461, Q2MHR2, Q96S14, Q9UJI0	Gene names	FBXL16, C16orf22, FBL16
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 16 (F-box and leucine-rich repeat protein 16).

FXL13_MOUSE
NC score	0.502218 (rank : 16)	θ value	4.0297e-08 (rank : 16)
Query Neighborhood Hits	217	Target Neighborhood Hits	70	Shared Neighborhood Hits	42
SwissProt Accessions	Q8CDU4, Q8CDE9	Gene names	Fbxl13
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 13 (F-box and leucine-rich repeat protein 13).

FXL13_HUMAN
NC score	0.477753 (rank : 17)	θ value	2.88788e-06 (rank : 23)
Query Neighborhood Hits	217	Target Neighborhood Hits	81	Shared Neighborhood Hits	39
SwissProt Accessions	Q8NEE6, Q6UVW7, Q6UVW8, Q75MN5, Q86UJ5, Q8N7Y4, Q8TCL2, Q8WUF9, Q8WUG0	Gene names	FBXL13, FBL13
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 13 (F-box and leucine-rich repeat protein 13).

FBX37_HUMAN
NC score	0.472283 (rank : 18)	θ value	1.69304e-06 (rank : 22)
Query Neighborhood Hits	217	Target Neighborhood Hits	38	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H469, Q49AL7, Q5JWA5	Gene names	FBXL15, FBXO37
Domain Architecture	No domain graphic available
Description	F-box only protein 37 (F-box/LRR-repeat protein 15).

SKP2_HUMAN
NC score	0.460003 (rank : 19)	θ value	4.1701e-05 (rank : 28)
Query Neighborhood Hits	217	Target Neighborhood Hits	79	Shared Neighborhood Hits	40
SwissProt Accessions	Q13309, Q8TDZ0, Q8TDZ1, Q9BV69	Gene names	SKP2, FBXL1
Domain Architecture
Description	S-phase kinase-associated protein 2 (F-box protein Skp2) (Cyclin A/CDK2-associated protein p45) (p45skp2) (F-box/LRR-repeat protein 1).

SKP2_MOUSE
NC score	0.447250 (rank : 20)	θ value	3.77169e-06 (rank : 24)
Query Neighborhood Hits	217	Target Neighborhood Hits	69	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Z0Z3, Q8BSG7, Q8C8Y9, Q8CB22, Q99J53	Gene names	Skp2
Domain Architecture
Description	S-phase kinase-associated protein 2 (F-box protein Skp2) (Cyclin A/CDK2-associated protein p45) (F-box/WD-40 protein 1) (FWD1).

FBX37_MOUSE
NC score	0.437496 (rank : 21)	θ value	9.92553e-07 (rank : 20)
Query Neighborhood Hits	217	Target Neighborhood Hits	37	Shared Neighborhood Hits	28
SwissProt Accessions	Q91W61	Gene names	Fbxl15, Fbxo37
Domain Architecture	No domain graphic available
Description	F-box only protein 37 (F-box/LRR-repeat protein 15).

DNMT1_MOUSE
NC score	0.390334 (rank : 22)	θ value	4.76016e-09 (rank : 14)
Query Neighborhood Hits	217	Target Neighborhood Hits	137	Shared Neighborhood Hits	25
SwissProt Accessions	P13864, P97413, Q80ZU3, Q9CSC6, Q9QXX6	Gene names	Dnmt1, Dnmt, Met1, Uim
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase MmuI) (DNA MTase MmuI) (MCMT) (M.MmuI) (Met-1).

FBXL4_HUMAN
NC score	0.387545 (rank : 23)	θ value	0.00509761 (rank : 35)
Query Neighborhood Hits	217	Target Neighborhood Hits	54	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UKA2, O95919, Q9UJU0	Gene names	FBXL4, FBL4, FBL5
Domain Architecture
Description	F-box/LRR-repeat protein 4 (F-box and leucine-rich repeat protein 4) (F-box protein FBL4/FBL5).

MBD1_HUMAN
NC score	0.366222 (rank : 24)	θ value	1.29631e-06 (rank : 21)
Query Neighborhood Hits	217	Target Neighborhood Hits	77	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UIS9, O15248, O95241, Q7Z7B5, Q8N4W4, Q9UNZ6, Q9UNZ7, Q9UNZ8, Q9UNZ9	Gene names	MBD1, PCM1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 1 (Methyl-CpG-binding protein MBD1) (Protein containing methyl-CpG-binding domain 1).

DNMT1_HUMAN
NC score	0.356500 (rank : 25)	θ value	3.08544e-08 (rank : 15)
Query Neighborhood Hits	217	Target Neighborhood Hits	401	Shared Neighborhood Hits	40
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

MBD1_MOUSE
NC score	0.349753 (rank : 26)	θ value	4.92598e-06 (rank : 25)
Query Neighborhood Hits	217	Target Neighborhood Hits	72	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Z2E2, Q792D6, Q8CCL9, Q9DC19	Gene names	Mbd1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 1 (Methyl-CpG-binding protein MBD1).

CXCC1_MOUSE
NC score	0.348118 (rank : 27)	θ value	2.61198e-07 (rank : 19)
Query Neighborhood Hits	217	Target Neighborhood Hits	124	Shared Neighborhood Hits	25
SwissProt Accessions	Q9CWW7	Gene names	Cxxc1, Cgbp, Pccx1
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

CXCC1_HUMAN
NC score	0.345190 (rank : 28)	θ value	2.61198e-07 (rank : 18)
Query Neighborhood Hits	217	Target Neighborhood Hits	143	Shared Neighborhood Hits	24
SwissProt Accessions	Q9P0U4, Q8N2W4, Q96BC8, Q9P2V7	Gene names	CXXC1, CGBP, PCCX1, PHF18
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

FXL22_MOUSE
NC score	0.344654 (rank : 29)	θ value	0.00390308 (rank : 31)
Query Neighborhood Hits	217	Target Neighborhood Hits	40	Shared Neighborhood Hits	31
SwissProt Accessions	Q8C7B6, Q8C3G3, Q8C3V6	Gene names	Fbxl22
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 22 (F-box and leucine-rich repeat protein 22).

FXL12_MOUSE
NC score	0.329044 (rank : 30)	θ value	0.0431538 (rank : 39)
Query Neighborhood Hits	217	Target Neighborhood Hits	79	Shared Neighborhood Hits	40
SwissProt Accessions	Q9EPX5, Q3UVH7, Q8CDX0, Q9CY04, Q9QZN5	Gene names	Fbxl12, Fbl12
Domain Architecture
Description	F-box/LRR-repeat protein 12 (F-box and leucine-rich repeat protein 12) (F-box protein FBL12).

FXL12_HUMAN
NC score	0.316189 (rank : 31)	θ value	0.125558 (rank : 50)
Query Neighborhood Hits	217	Target Neighborhood Hits	86	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NXK8, Q9H5K4	Gene names	FBXL12, FBL12
Domain Architecture
Description	F-box/LRR-repeat protein 12 (F-box and leucine-rich repeat protein 12) (F-box protein FBL12).

PHF8_MOUSE
NC score	0.287180 (rank : 32)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	217	Target Neighborhood Hits	96	Shared Neighborhood Hits	14
SwissProt Accessions	Q80TJ7, Q8BLX8, Q8BLY0, Q8BZ61, Q8CG26	Gene names	Phf8, Kiaa1111
Domain Architecture	No domain graphic available
Description	PHD finger protein 8.

PHF8_HUMAN
NC score	0.287052 (rank : 33)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	217	Target Neighborhood Hits	105	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UPP1, Q5H9U5, Q5VUJ4, Q7Z6D4, Q9HAH2	Gene names	PHF8, KIAA1111, ZNF422
Domain Architecture	No domain graphic available
Description	PHD finger protein 8.

K1718_MOUSE
NC score	0.283444 (rank : 34)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	217	Target Neighborhood Hits	98	Shared Neighborhood Hits	12
SwissProt Accessions	Q3UWM4, Q3UWN8, Q6ZPJ5, Q8C969, Q8C9E0, Q91VX8	Gene names	Kiaa1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

K1718_HUMAN
NC score	0.280534 (rank : 35)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	217	Target Neighborhood Hits	114	Shared Neighborhood Hits	10
SwissProt Accessions	Q6ZMT4, Q6MZL8, Q9C0E5	Gene names	KIAA1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

PHF2_MOUSE
NC score	0.273059 (rank : 36)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	217	Target Neighborhood Hits	241	Shared Neighborhood Hits	22
SwissProt Accessions	Q9WTU0, Q80WA8	Gene names	Phf2
Domain Architecture
Description	PHD finger protein 2 (GRC5).

PHF2_HUMAN
NC score	0.271721 (rank : 37)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	217	Target Neighborhood Hits	208	Shared Neighborhood Hits	19
SwissProt Accessions	O75151, Q8N3K2, Q9Y6N4	Gene names	PHF2, KIAA0662
Domain Architecture
Description	PHD finger protein 2 (GRC5).

MLL4_HUMAN
NC score	0.253568 (rank : 38)	θ value	1.99992e-07 (rank : 17)
Query Neighborhood Hits	217	Target Neighborhood Hits	722	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

FBXL6_MOUSE
NC score	0.249660 (rank : 39)	θ value	0.163984 (rank : 52)
Query Neighborhood Hits	217	Target Neighborhood Hits	55	Shared Neighborhood Hits	32
SwissProt Accessions	Q9QXW0, Q9JJD7	Gene names	Fbxl6, Fbl6
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 6 (F-box and leucine-rich repeat protein 6) (F-box protein FBL6).

FBXL5_MOUSE
NC score	0.242149 (rank : 40)	θ value	0.0961366 (rank : 46)
Query Neighborhood Hits	217	Target Neighborhood Hits	103	Shared Neighborhood Hits	43
SwissProt Accessions	Q8C2S5, Q3TWC9, Q80XI5, Q8BGF5, Q8BNL3, Q8C3Q8	Gene names	Fbxl5
Domain Architecture
Description	F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5).

FBXL6_HUMAN
NC score	0.238729 (rank : 41)	θ value	0.365318 (rank : 62)
Query Neighborhood Hits	217	Target Neighborhood Hits	65	Shared Neighborhood Hits	29
SwissProt Accessions	Q8N531, Q9H5W9, Q9UKC7	Gene names	FBXL6, FBL6
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 6 (F-box and leucine-rich repeat protein 6) (F-box protein FBL6) (FBL6A).

FBXL5_HUMAN
NC score	0.232320 (rank : 42)	θ value	0.125558 (rank : 49)
Query Neighborhood Hits	217	Target Neighborhood Hits	111	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UKA1, Q8NHP3, Q9NXN2, Q9P0I0, Q9P0X5, Q9UJT7, Q9UKC8	Gene names	FBXL5, FBL4, FBL5, FLR1
Domain Architecture
Description	F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5) (F-box protein FBL4/FBL5) (p45SKP2-like protein).

HRX_HUMAN
NC score	0.221580 (rank : 43)	θ value	0.00020696 (rank : 29)
Query Neighborhood Hits	217	Target Neighborhood Hits	825	Shared Neighborhood Hits	71
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

FBXW8_MOUSE
NC score	0.158100 (rank : 44)	θ value	0.0961366 (rank : 47)
Query Neighborhood Hits	217	Target Neighborhood Hits	162	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BIA4, Q8BI62, Q8BI75, Q8BI76, Q8CID8, Q921Z1	Gene names	Fbxw8
Domain Architecture
Description	F-box/WD repeat protein 8 (F-box and WD-40 domain protein 8).

FBX11_HUMAN
NC score	0.154198 (rank : 45)	θ value	3.0926 (rank : 138)
Query Neighborhood Hits	217	Target Neighborhood Hits	72	Shared Neighborhood Hits	33
SwissProt Accessions	Q86XK2, Q8IXG3, Q96E90, Q9H6V8, Q9H9L1, Q9NR14, Q9UFK1, Q9UHI1, Q9UKC2	Gene names	FBXO11, FBX11, VIT1
Domain Architecture
Description	F-box only protein 11 (Vitiligo-associated protein VIT-1).

FBX16_HUMAN
NC score	0.149867 (rank : 46)	θ value	0.0961366 (rank : 45)
Query Neighborhood Hits	217	Target Neighborhood Hits	51	Shared Neighborhood Hits	25
SwissProt Accessions	Q8IX29, Q3T1B4	Gene names	FBXO16, FBX16
Domain Architecture
Description	F-box only protein 16.

FBXW8_HUMAN
NC score	0.146470 (rank : 47)	θ value	0.62314 (rank : 77)
Query Neighborhood Hits	217	Target Neighborhood Hits	192	Shared Neighborhood Hits	31
SwissProt Accessions	Q8N3Y1, Q9UK95	Gene names	FBXW8, FBW6, FBW8, FBX29, FBXO29, FBXW6
Domain Architecture
Description	F-box/WD repeat protein 8 (F-box and WD-40 domain protein 8) (F-box only protein 29).

FBXL8_HUMAN
NC score	0.142334 (rank : 48)	θ value	1.38821 (rank : 103)
Query Neighborhood Hits	217	Target Neighborhood Hits	43	Shared Neighborhood Hits	32
SwissProt Accessions	Q96CD0, Q9NUM0	Gene names	FBXL8, FBL8
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 8 (F-box and leucine-rich repeat protein 8) (F-box protein FBL8).

FBXL8_MOUSE
NC score	0.137583 (rank : 49)	θ value	0.21417 (rank : 54)
Query Neighborhood Hits	217	Target Neighborhood Hits	38	Shared Neighborhood Hits	28
SwissProt Accessions	Q8CIG9, Q9QZN7	Gene names	Fbxl8, Fbl8
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 8 (F-box and leucine-rich repeat protein 8) (F-box protein FBL8).

CXXC6_HUMAN
NC score	0.134593 (rank : 50)	θ value	1.38821 (rank : 100)
Query Neighborhood Hits	217	Target Neighborhood Hits	180	Shared Neighborhood Hits	28
SwissProt Accessions	Q8NFU7, Q5VUP7, Q7Z6B6, Q8TCR1, Q9C0I7	Gene names	CXXC6, KIAA1676, LCX
Domain Architecture	No domain graphic available
Description	CXXC-type zinc finger protein 6 (Leukemia-associated protein with a CXXC domain).

PRRT3_HUMAN
NC score	0.125215 (rank : 51)	θ value	0.00102713 (rank : 30)
Query Neighborhood Hits	217	Target Neighborhood Hits	998	Shared Neighborhood Hits	105
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

PHF10_HUMAN
NC score	0.111410 (rank : 52)	θ value	0.0563607 (rank : 42)
Query Neighborhood Hits	217	Target Neighborhood Hits	151	Shared Neighborhood Hits	25
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

MLL3_MOUSE
NC score	0.107773 (rank : 53)	θ value	0.813845 (rank : 85)
Query Neighborhood Hits	217	Target Neighborhood Hits	1399	Shared Neighborhood Hits	120
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

PHF10_MOUSE
NC score	0.106923 (rank : 54)	θ value	0.125558 (rank : 51)
Query Neighborhood Hits	217	Target Neighborhood Hits	131	Shared Neighborhood Hits	24
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

MLL3_HUMAN
NC score	0.105081 (rank : 55)	θ value	0.813845 (rank : 84)
Query Neighborhood Hits	217	Target Neighborhood Hits	1644	Shared Neighborhood Hits	118
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

FBX16_MOUSE
NC score	0.104961 (rank : 56)	θ value	4.03905 (rank : 147)
Query Neighborhood Hits	217	Target Neighborhood Hits	39	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QZM9, Q3TP74, Q8C5V6	Gene names	Fbxo16, Fbx16
Domain Architecture
Description	F-box only protein 16.

MYST3_HUMAN
NC score	0.099528 (rank : 57)	θ value	0.21417 (rank : 55)
Query Neighborhood Hits	217	Target Neighborhood Hits	772	Shared Neighborhood Hits	51
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

MYST3_MOUSE
NC score	0.095641 (rank : 58)	θ value	0.62314 (rank : 80)
Query Neighborhood Hits	217	Target Neighborhood Hits	688	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

FBX41_HUMAN
NC score	0.095511 (rank : 59)	θ value	1.06291 (rank : 92)
Query Neighborhood Hits	217	Target Neighborhood Hits	475	Shared Neighborhood Hits	34
SwissProt Accessions	Q8TF61	Gene names	FBXO41, FBX41, KIAA1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

FXL21_MOUSE
NC score	0.094562 (rank : 60)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	217	Target Neighborhood Hits	49	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BFZ4, Q8BIJ8, Q8BIW5	Gene names	Fbxl21, Fbl21, Fbxl3b
Domain Architecture
Description	F-box/LRR-repeat protein 21 (F-box and leucine-rich repeat protein 21) (F-box/LRR-repeat protein 3B) (F-box and leucine-rich repeat protein 3B).

IWS1_HUMAN
NC score	0.093241 (rank : 61)	θ value	0.00390308 (rank : 32)
Query Neighborhood Hits	217	Target Neighborhood Hits	1241	Shared Neighborhood Hits	70
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MLL2_HUMAN
NC score	0.080161 (rank : 62)	θ value	8.99809 (rank : 203)
Query Neighborhood Hits	217	Target Neighborhood Hits	1788	Shared Neighborhood Hits	110
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

FBXL3_HUMAN
NC score	0.079948 (rank : 63)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	217	Target Neighborhood Hits	36	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UKT7, Q9P122	Gene names	FBXL3, FBL3A, FBXL3A
Domain Architecture
Description	F-box/LRR-repeat protein 3 (F-box/LRR-repeat protein 3A) (F-box and leucine-rich repeat protein 3A).

OGFR_MOUSE
NC score	0.078903 (rank : 64)	θ value	0.0961366 (rank : 48)
Query Neighborhood Hits	217	Target Neighborhood Hits	584	Shared Neighborhood Hits	64
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

FBX41_MOUSE
NC score	0.078173 (rank : 65)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	217	Target Neighborhood Hits	430	Shared Neighborhood Hits	28
SwissProt Accessions	Q6NS60, Q6P7W4, Q6ZPG1	Gene names	Fbxo41, D6Ertd538e, Kiaa1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

FBXL3_MOUSE
NC score	0.077257 (rank : 66)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	217	Target Neighborhood Hits	37	Shared Neighborhood Hits	25
SwissProt Accessions	Q8C4V4, Q80V32, Q8K1W0, Q9QXW1	Gene names	Fbxl3, Fbl3a, Fbxl3a
Domain Architecture
Description	F-box/LRR-repeat protein 3 (F-box/LRR-repeat protein 3A) (F-box and leucine-rich repeat protein 3A).

PRB4S_HUMAN
NC score	0.076459 (rank : 67)	θ value	0.0563607 (rank : 43)
Query Neighborhood Hits	217	Target Neighborhood Hits	330	Shared Neighborhood Hits	39
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

FBX39_MOUSE
NC score	0.076374 (rank : 68)	θ value	4.03905 (rank : 148)
Query Neighborhood Hits	217	Target Neighborhood Hits	34	Shared Neighborhood Hits	23
SwissProt Accessions	Q5NBU5	Gene names	Fbxo39
Domain Architecture	No domain graphic available
Description	F-box only protein 39.

FBX39_HUMAN
NC score	0.075112 (rank : 69)	θ value	1.38821 (rank : 102)
Query Neighborhood Hits	217	Target Neighborhood Hits	23	Shared Neighborhood Hits	17
SwissProt Accessions	Q8N4B4	Gene names	FBXO39, FBX39
Domain Architecture	No domain graphic available
Description	F-box only protein 39.

SON_HUMAN
NC score	0.074189 (rank : 70)	θ value	0.813845 (rank : 88)
Query Neighborhood Hits	217	Target Neighborhood Hits	1568	Shared Neighborhood Hits	116
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

WIRE_MOUSE
NC score	0.073485 (rank : 71)	θ value	0.21417 (rank : 57)
Query Neighborhood Hits	217	Target Neighborhood Hits	310	Shared Neighborhood Hits	41
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

SET1A_HUMAN
NC score	0.073443 (rank : 72)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	217	Target Neighborhood Hits	690	Shared Neighborhood Hits	50
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

NPBL_MOUSE
NC score	0.073163 (rank : 73)	θ value	0.163984 (rank : 53)
Query Neighborhood Hits	217	Target Neighborhood Hits	1041	Shared Neighborhood Hits	58
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

IWS1_MOUSE
NC score	0.071941 (rank : 74)	θ value	1.38821 (rank : 104)
Query Neighborhood Hits	217	Target Neighborhood Hits	1258	Shared Neighborhood Hits	74
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

FA47B_HUMAN
NC score	0.071862 (rank : 75)	θ value	1.06291 (rank : 91)
Query Neighborhood Hits	217	Target Neighborhood Hits	431	Shared Neighborhood Hits	75
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

FXL21_HUMAN
NC score	0.071166 (rank : 76)	θ value	6.88961 (rank : 177)
Query Neighborhood Hits	217	Target Neighborhood Hits	43	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UKT6	Gene names	FBXL21, FBL21, FBL3, FBXL3B
Domain Architecture
Description	F-box/LRR-repeat protein 21 (F-box and leucine-rich repeat protein 21) (F-box/LRR-repeat protein 3B) (F-box and leucine-rich repeat protein 3B).

FBW12_HUMAN
NC score	0.070911 (rank : 77)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	217	Target Neighborhood Hits	60	Shared Neighborhood Hits	23
SwissProt Accessions	Q6X9E4	Gene names	FBXW12, FBW12, FBXO12, FBXO35
Domain Architecture	No domain graphic available
Description	F-box/WD repeat protein 12 (F-box and WD-40 domain protein 12) (F-box only protein 35).

NIPBL_HUMAN
NC score	0.070538 (rank : 78)	θ value	0.0193708 (rank : 36)
Query Neighborhood Hits	217	Target Neighborhood Hits	1311	Shared Neighborhood Hits	63
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

WIRE_HUMAN
NC score	0.069787 (rank : 79)	θ value	0.47712 (rank : 75)
Query Neighborhood Hits	217	Target Neighborhood Hits	329	Shared Neighborhood Hits	41
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

OGFR_HUMAN
NC score	0.069770 (rank : 80)	θ value	3.0926 (rank : 142)
Query Neighborhood Hits	217	Target Neighborhood Hits	1582	Shared Neighborhood Hits	115
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

YLPM1_HUMAN
NC score	0.069616 (rank : 81)	θ value	0.813845 (rank : 89)
Query Neighborhood Hits	217	Target Neighborhood Hits	670	Shared Neighborhood Hits	60
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

CRSP7_HUMAN
NC score	0.068491 (rank : 82)	θ value	0.47712 (rank : 69)
Query Neighborhood Hits	217	Target Neighborhood Hits	247	Shared Neighborhood Hits	30
SwissProt Accessions	O95402	Gene names	CRSP7, ARC70
Domain Architecture
Description	CRSP complex subunit 7 (Cofactor required for Sp1 transcriptional activation subunit 7) (Transcriptional coactivator CRSP70) (Activator- recruited cofactor 70 kDa component) (ARC70).

PHF14_MOUSE
NC score	0.068467 (rank : 83)	θ value	1.38821 (rank : 105)
Query Neighborhood Hits	217	Target Neighborhood Hits	342	Shared Neighborhood Hits	34
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

RGS3_MOUSE
NC score	0.068132 (rank : 84)	θ value	0.279714 (rank : 60)
Query Neighborhood Hits	217	Target Neighborhood Hits	1621	Shared Neighborhood Hits	119
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

MYST4_HUMAN
NC score	0.066813 (rank : 85)	θ value	8.99809 (rank : 204)
Query Neighborhood Hits	217	Target Neighborhood Hits	671	Shared Neighborhood Hits	48
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

PHF14_HUMAN
NC score	0.066464 (rank : 86)	θ value	2.36792 (rank : 120)
Query Neighborhood Hits	217	Target Neighborhood Hits	447	Shared Neighborhood Hits	34
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

IER5_MOUSE
NC score	0.066455 (rank : 87)	θ value	0.279714 (rank : 59)
Query Neighborhood Hits	217	Target Neighborhood Hits	110	Shared Neighborhood Hits	14
SwissProt Accessions	O89113, Q8CGI0	Gene names	Ier5
Domain Architecture	No domain graphic available
Description	Immediate early response gene 5 protein.

MYST4_MOUSE
NC score	0.066287 (rank : 88)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	217	Target Neighborhood Hits	416	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

SRRM1_MOUSE
NC score	0.065750 (rank : 89)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	217	Target Neighborhood Hits	966	Shared Neighborhood Hits	79
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

PRP1_HUMAN
NC score	0.064123 (rank : 90)	θ value	0.365318 (rank : 66)
Query Neighborhood Hits	217	Target Neighborhood Hits	385	Shared Neighborhood Hits	40
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PRB3_HUMAN
NC score	0.063714 (rank : 91)	θ value	1.06291 (rank : 97)
Query Neighborhood Hits	217	Target Neighborhood Hits	318	Shared Neighborhood Hits	41
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

FBX33_HUMAN
NC score	0.063255 (rank : 92)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	217	Target Neighborhood Hits	42	Shared Neighborhood Hits	23
SwissProt Accessions	Q7Z6M2, Q6PIR2, Q86TR2, Q86YE0	Gene names	FBXO33, FBX33
Domain Architecture	No domain graphic available
Description	F-box only protein 33.

PTDSR_HUMAN
NC score	0.061976 (rank : 93)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	217	Target Neighborhood Hits	22	Shared Neighborhood Hits	5
SwissProt Accessions	Q6NYC1, Q86VY0, Q8IUM5, Q9Y4E2	Gene names	PTDSR, KIAA0585
Domain Architecture	No domain graphic available
Description	Protein PTDSR (Phosphatidylserine receptor).

PTDSR_MOUSE
NC score	0.061901 (rank : 94)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	217	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ERI5, Q80TX1	Gene names	Ptdsr, Kiaa0585
Domain Architecture	No domain graphic available
Description	Protein PTDSR (Phosphatidylserine receptor) (Apoptotic cell clearance receptor PtdSerR).

BAZ1B_MOUSE
NC score	0.061450 (rank : 95)	θ value	0.813845 (rank : 83)
Query Neighborhood Hits	217	Target Neighborhood Hits	394	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

K1802_MOUSE
NC score	0.061206 (rank : 96)	θ value	0.47712 (rank : 72)
Query Neighborhood Hits	217	Target Neighborhood Hits	1596	Shared Neighborhood Hits	108
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

VCX3_HUMAN
NC score	0.060880 (rank : 97)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	217	Target Neighborhood Hits	105	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NNX9, Q9P0H4	Gene names	VCX3A, VCX3, VCX8R, VCXA
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 3 (VCX-A protein) (Variably charged protein X-A) (Variable charge protein on X with eight repeats) (VCX- 8r).

BAT2_HUMAN
NC score	0.060842 (rank : 98)	θ value	2.36792 (rank : 112)
Query Neighborhood Hits	217	Target Neighborhood Hits	931	Shared Neighborhood Hits	91
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

GA2L2_MOUSE
NC score	0.060644 (rank : 99)	θ value	0.62314 (rank : 79)
Query Neighborhood Hits	217	Target Neighborhood Hits	395	Shared Neighborhood Hits	66
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

SETD8_HUMAN
NC score	0.060235 (rank : 100)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	217	Target Neighborhood Hits	114	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NQR1, Q86W83, Q8TD09	Gene names	SETD8, PRSET7, SET07, SET8
Domain Architecture
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8) (PR/SET domain-containing protein 07) (PR/SET07) (PR-Set7).

VCXC_HUMAN
NC score	0.060044 (rank : 101)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	217	Target Neighborhood Hits	139	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H321	Gene names	VCXC
Domain Architecture	No domain graphic available
Description	VCX-C protein (Variably charged protein X-C).

CS016_HUMAN
NC score	0.059749 (rank : 102)	θ value	0.365318 (rank : 61)
Query Neighborhood Hits	217	Target Neighborhood Hits	310	Shared Neighborhood Hits	31
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

SON_MOUSE
NC score	0.059564 (rank : 103)	θ value	0.365318 (rank : 67)
Query Neighborhood Hits	217	Target Neighborhood Hits	957	Shared Neighborhood Hits	77
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

WASIP_HUMAN
NC score	0.059230 (rank : 104)	θ value	4.03905 (rank : 152)
Query Neighborhood Hits	217	Target Neighborhood Hits	458	Shared Neighborhood Hits	44
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

MILK1_MOUSE
NC score	0.058177 (rank : 105)	θ value	0.365318 (rank : 65)
Query Neighborhood Hits	217	Target Neighborhood Hits	788	Shared Neighborhood Hits	83
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

SRRM1_HUMAN
NC score	0.057839 (rank : 106)	θ value	6.88961 (rank : 189)
Query Neighborhood Hits	217	Target Neighborhood Hits	690	Shared Neighborhood Hits	58
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

LCP2_HUMAN
NC score	0.057211 (rank : 107)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	217	Target Neighborhood Hits	531	Shared Neighborhood Hits	71
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

BAT2_MOUSE
NC score	0.056604 (rank : 108)	θ value	4.03905 (rank : 146)
Query Neighborhood Hits	217	Target Neighborhood Hits	947	Shared Neighborhood Hits	89
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

WBP11_MOUSE
NC score	0.056374 (rank : 109)	θ value	2.36792 (rank : 129)
Query Neighborhood Hits	217	Target Neighborhood Hits	362	Shared Neighborhood Hits	37
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

PHF22_MOUSE
NC score	0.056014 (rank : 110)	θ value	5.27518 (rank : 165)
Query Neighborhood Hits	217	Target Neighborhood Hits	89	Shared Neighborhood Hits	14
SwissProt Accessions	Q9D168, Q3U2Q5, Q921U2	Gene names	Ints12, Phf22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

IF4B_HUMAN
NC score	0.055775 (rank : 111)	θ value	1.06291 (rank : 93)
Query Neighborhood Hits	217	Target Neighborhood Hits	417	Shared Neighborhood Hits	36
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

CECR2_HUMAN
NC score	0.055620 (rank : 112)	θ value	1.38821 (rank : 99)
Query Neighborhood Hits	217	Target Neighborhood Hits	543	Shared Neighborhood Hits	66
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

FBX27_MOUSE
NC score	0.055583 (rank : 113)	θ value	0.47712 (rank : 70)
Query Neighborhood Hits	217	Target Neighborhood Hits	29	Shared Neighborhood Hits	19
SwissProt Accessions	Q6DIA9, Q3TYP0, Q8BKF7	Gene names	Fbxo27
Domain Architecture	No domain graphic available
Description	F-box only protein 27.

VASP_HUMAN
NC score	0.055563 (rank : 114)	θ value	0.365318 (rank : 68)
Query Neighborhood Hits	217	Target Neighborhood Hits	201	Shared Neighborhood Hits	24
SwissProt Accessions	P50552, Q6PIZ1, Q93035	Gene names	VASP
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

NACAM_MOUSE
NC score	0.055371 (rank : 115)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	217	Target Neighborhood Hits	1866	Shared Neighborhood Hits	122
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

WBP11_HUMAN
NC score	0.054914 (rank : 116)	θ value	2.36792 (rank : 128)
Query Neighborhood Hits	217	Target Neighborhood Hits	354	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

PRR12_HUMAN
NC score	0.054854 (rank : 117)	θ value	4.03905 (rank : 149)
Query Neighborhood Hits	217	Target Neighborhood Hits	460	Shared Neighborhood Hits	41
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

FBX36_HUMAN
NC score	0.054728 (rank : 118)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	217	Target Neighborhood Hits	30	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NEA4, Q8WWD4	Gene names	FBXO36, FBX36
Domain Architecture	No domain graphic available
Description	F-box only protein 36.

DIDO1_HUMAN
NC score	0.054574 (rank : 119)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	217	Target Neighborhood Hits	960	Shared Neighborhood Hits	91
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

FA47A_HUMAN
NC score	0.053997 (rank : 120)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	217	Target Neighborhood Hits	451	Shared Neighborhood Hits	66
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

NGEF_MOUSE
NC score	0.053692 (rank : 121)	θ value	0.00390308 (rank : 33)
Query Neighborhood Hits	217	Target Neighborhood Hits	228	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

VCX1_HUMAN
NC score	0.053168 (rank : 122)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	217	Target Neighborhood Hits	129	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H320, Q9P0H3	Gene names	VCX, VCX1, VCX10R, VCXB1
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 1 (VCX-B1 protein) (Variably charged protein X-B1) (Variable charge protein on X with ten repeats) (VCX- 10r).

PRRT3_MOUSE
NC score	0.052795 (rank : 123)	θ value	5.27518 (rank : 166)
Query Neighborhood Hits	217	Target Neighborhood Hits	162	Shared Neighborhood Hits	21
SwissProt Accessions	Q6PE13	Gene names	Prrt3
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

BAZ1B_HUMAN
NC score	0.052607 (rank : 124)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	217	Target Neighborhood Hits	701	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

CD2_HUMAN
NC score	0.052143 (rank : 125)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	217	Target Neighborhood Hits	504	Shared Neighborhood Hits	81
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

FBX27_HUMAN
NC score	0.051358 (rank : 126)	θ value	3.0926 (rank : 139)
Query Neighborhood Hits	217	Target Neighborhood Hits	39	Shared Neighborhood Hits	22
SwissProt Accessions	Q8NI29, Q96C87	Gene names	FBXO27, FBG5, FBX27
Domain Architecture
Description	F-box only protein 27 (F-box/G-domain protein 5).

NCOA6_HUMAN
NC score	0.051193 (rank : 127)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	217	Target Neighborhood Hits	1202	Shared Neighborhood Hits	102
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

MDC1_HUMAN
NC score	0.050701 (rank : 128)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	217	Target Neighborhood Hits	1446	Shared Neighborhood Hits	97
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

VASP_MOUSE
NC score	0.048065 (rank : 129)	θ value	0.62314 (rank : 81)
Query Neighborhood Hits	217	Target Neighborhood Hits	195	Shared Neighborhood Hits	22
SwissProt Accessions	P70460, Q3TAP0, Q3TCD2, Q3U0C2, Q3UDF1, Q91VD2, Q9R214	Gene names	Vasp
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

CIC_HUMAN
NC score	0.046969 (rank : 130)	θ value	5.27518 (rank : 155)
Query Neighborhood Hits	217	Target Neighborhood Hits	992	Shared Neighborhood Hits	102
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

PRP2_MOUSE
NC score	0.046880 (rank : 131)	θ value	8.99809 (rank : 207)
Query Neighborhood Hits	217	Target Neighborhood Hits	347	Shared Neighborhood Hits	36
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

TACC2_HUMAN
NC score	0.046867 (rank : 132)	θ value	0.0431538 (rank : 40)
Query Neighborhood Hits	217	Target Neighborhood Hits	856	Shared Neighborhood Hits	46
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

NCOR1_HUMAN
NC score	0.044863 (rank : 133)	θ value	0.21417 (rank : 56)
Query Neighborhood Hits	217	Target Neighborhood Hits	577	Shared Neighborhood Hits	31
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

PSL1_HUMAN
NC score	0.044731 (rank : 134)	θ value	8.99809 (rank : 208)
Query Neighborhood Hits	217	Target Neighborhood Hits	650	Shared Neighborhood Hits	86
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

PF21A_MOUSE
NC score	0.044374 (rank : 135)	θ value	3.0926 (rank : 143)
Query Neighborhood Hits	217	Target Neighborhood Hits	285	Shared Neighborhood Hits	26
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

ASTL_HUMAN
NC score	0.044212 (rank : 136)	θ value	0.62314 (rank : 76)
Query Neighborhood Hits	217	Target Neighborhood Hits	252	Shared Neighborhood Hits	33
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

WASL_MOUSE
NC score	0.044114 (rank : 137)	θ value	2.36792 (rank : 127)
Query Neighborhood Hits	217	Target Neighborhood Hits	339	Shared Neighborhood Hits	36
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WASL_HUMAN
NC score	0.044106 (rank : 138)	θ value	1.06291 (rank : 98)
Query Neighborhood Hits	217	Target Neighborhood Hits	312	Shared Neighborhood Hits	34
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

YLPM1_MOUSE
NC score	0.043388 (rank : 139)	θ value	5.27518 (rank : 172)
Query Neighborhood Hits	217	Target Neighborhood Hits	505	Shared Neighborhood Hits	33
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

JPH2_HUMAN
NC score	0.043216 (rank : 140)	θ value	0.47712 (rank : 71)
Query Neighborhood Hits	217	Target Neighborhood Hits	639	Shared Neighborhood Hits	85
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

BTBDC_HUMAN
NC score	0.042918 (rank : 141)	θ value	1.81305 (rank : 106)
Query Neighborhood Hits	217	Target Neighborhood Hits	248	Shared Neighborhood Hits	27
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

MILK1_HUMAN
NC score	0.041914 (rank : 142)	θ value	0.365318 (rank : 64)
Query Neighborhood Hits	217	Target Neighborhood Hits	427	Shared Neighborhood Hits	43
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

CPSF6_MOUSE
NC score	0.041842 (rank : 143)	θ value	2.36792 (rank : 115)
Query Neighborhood Hits	217	Target Neighborhood Hits	356	Shared Neighborhood Hits	34
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

K1045_HUMAN
NC score	0.041483 (rank : 144)	θ value	3.0926 (rank : 140)
Query Neighborhood Hits	217	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UPV7, Q58FE9, Q5T662	Gene names	KIAA1045
Domain Architecture	No domain graphic available
Description	Protein KIAA1045.

CPSF6_HUMAN
NC score	0.041464 (rank : 145)	θ value	2.36792 (rank : 114)
Query Neighborhood Hits	217	Target Neighborhood Hits	359	Shared Neighborhood Hits	33
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

CT174_HUMAN
NC score	0.041265 (rank : 146)	θ value	2.36792 (rank : 116)
Query Neighborhood Hits	217	Target Neighborhood Hits	181	Shared Neighborhood Hits	31
SwissProt Accessions	Q5JPB2, Q5TDR4, Q8TCP0	Gene names	C20orf174
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf174.

ENAH_MOUSE
NC score	0.040817 (rank : 147)	θ value	3.0926 (rank : 137)
Query Neighborhood Hits	217	Target Neighborhood Hits	919	Shared Neighborhood Hits	49
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

JAD1A_HUMAN
NC score	0.040393 (rank : 148)	θ value	8.99809 (rank : 198)
Query Neighborhood Hits	217	Target Neighborhood Hits	328	Shared Neighborhood Hits	28
SwissProt Accessions	P29375	Gene names	JARID1A, RBBP2, RBP2
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1A (Retinoblastoma-binding protein 2) (RBBP-2).

ZYX_HUMAN
NC score	0.040157 (rank : 149)	θ value	0.0252991 (rank : 37)
Query Neighborhood Hits	217	Target Neighborhood Hits	387	Shared Neighborhood Hits	28
SwissProt Accessions	Q15942	Gene names	ZYX
Domain Architecture
Description	Zyxin (Zyxin-2).

CBP_HUMAN
NC score	0.039200 (rank : 150)	θ value	2.36792 (rank : 113)
Query Neighborhood Hits	217	Target Neighborhood Hits	941	Shared Neighborhood Hits	85
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

PF21A_HUMAN
NC score	0.038894 (rank : 151)	θ value	6.88961 (rank : 183)
Query Neighborhood Hits	217	Target Neighborhood Hits	303	Shared Neighborhood Hits	28
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

MBB1A_HUMAN
NC score	0.038611 (rank : 152)	θ value	6.88961 (rank : 180)
Query Neighborhood Hits	217	Target Neighborhood Hits	665	Shared Neighborhood Hits	62
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

SF3A2_HUMAN
NC score	0.038282 (rank : 153)	θ value	4.03905 (rank : 150)
Query Neighborhood Hits	217	Target Neighborhood Hits	263	Shared Neighborhood Hits	22
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

FRS3_MOUSE
NC score	0.037718 (rank : 154)	θ value	0.365318 (rank : 63)
Query Neighborhood Hits	217	Target Neighborhood Hits	168	Shared Neighborhood Hits	23
SwissProt Accessions	Q91WJ0	Gene names	Frs3, Frs2b
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (FRS2-beta).

TULP4_HUMAN
NC score	0.037692 (rank : 155)	θ value	2.36792 (rank : 126)
Query Neighborhood Hits	217	Target Neighborhood Hits	426	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

SF3A2_MOUSE
NC score	0.037298 (rank : 156)	θ value	5.27518 (rank : 168)
Query Neighborhood Hits	217	Target Neighborhood Hits	247	Shared Neighborhood Hits	27
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

GRIN1_MOUSE
NC score	0.036415 (rank : 157)	θ value	2.36792 (rank : 119)
Query Neighborhood Hits	217	Target Neighborhood Hits	337	Shared Neighborhood Hits	34
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

ATN1_HUMAN
NC score	0.036365 (rank : 158)	θ value	6.88961 (rank : 173)
Query Neighborhood Hits	217	Target Neighborhood Hits	676	Shared Neighborhood Hits	50
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

FBXW7_HUMAN
NC score	0.036120 (rank : 159)	θ value	5.27518 (rank : 159)
Query Neighborhood Hits	217	Target Neighborhood Hits	433	Shared Neighborhood Hits	38
SwissProt Accessions	Q969H0, Q96A16, Q96LE0, Q96RI2, Q9NUX6	Gene names	FBXW7, FBW7, FBX30, SEL10
Domain Architecture
Description	F-box/WD repeat protein 7 (F-box and WD-40 domain protein 7) (F-box protein FBX30) (hCdc4) (Archipelago homolog) (hAgo) (SEL-10).

FMNL_HUMAN
NC score	0.035541 (rank : 160)	θ value	6.88961 (rank : 176)
Query Neighborhood Hits	217	Target Neighborhood Hits	529	Shared Neighborhood Hits	40
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

FMNL_MOUSE
NC score	0.035052 (rank : 161)	θ value	2.36792 (rank : 118)
Query Neighborhood Hits	217	Target Neighborhood Hits	428	Shared Neighborhood Hits	34
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

FBXW7_MOUSE
NC score	0.034790 (rank : 162)	θ value	5.27518 (rank : 160)
Query Neighborhood Hits	217	Target Neighborhood Hits	365	Shared Neighborhood Hits	34
SwissProt Accessions	Q8VBV4, Q8CCS5, Q8VHP4	Gene names	Fbxw7, Fbw7, Fbwd6, Fbxw6
Domain Architecture
Description	F-box/WD repeat protein 7 (F-box and WD-40 domain protein 7) (F-box protein FBW7) (F-box protein Fbxw6) (F-box-WD40 repeat protein 6) (SEL-10).

TRI66_MOUSE
NC score	0.034692 (rank : 163)	θ value	4.03905 (rank : 151)
Query Neighborhood Hits	217	Target Neighborhood Hits	491	Shared Neighborhood Hits	43
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

ZYX_MOUSE
NC score	0.034426 (rank : 164)	θ value	0.62314 (rank : 82)
Query Neighborhood Hits	217	Target Neighborhood Hits	347	Shared Neighborhood Hits	25
SwissProt Accessions	Q62523, P70461	Gene names	Zyx
Domain Architecture
Description	Zyxin.

ARHGF_HUMAN
NC score	0.033833 (rank : 165)	θ value	3.0926 (rank : 131)
Query Neighborhood Hits	217	Target Neighborhood Hits	214	Shared Neighborhood Hits	21
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

SYN1_MOUSE
NC score	0.033652 (rank : 166)	θ value	2.36792 (rank : 123)
Query Neighborhood Hits	217	Target Neighborhood Hits	363	Shared Neighborhood Hits	38
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

CSKI1_HUMAN
NC score	0.033442 (rank : 167)	θ value	0.0431538 (rank : 38)
Query Neighborhood Hits	217	Target Neighborhood Hits	997	Shared Neighborhood Hits	77
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

TRI66_HUMAN
NC score	0.033423 (rank : 168)	θ value	2.36792 (rank : 125)
Query Neighborhood Hits	217	Target Neighborhood Hits	479	Shared Neighborhood Hits	40
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

FMN1B_MOUSE
NC score	0.033165 (rank : 169)	θ value	6.88961 (rank : 175)
Query Neighborhood Hits	217	Target Neighborhood Hits	447	Shared Neighborhood Hits	36
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

PRRT1_MOUSE
NC score	0.032985 (rank : 170)	θ value	3.0926 (rank : 144)
Query Neighborhood Hits	217	Target Neighborhood Hits	102	Shared Neighborhood Hits	14
SwissProt Accessions	O35449	Gene names	Prrt1, Ng5
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 1.

CSKI1_MOUSE
NC score	0.032933 (rank : 171)	θ value	1.06291 (rank : 90)
Query Neighborhood Hits	217	Target Neighborhood Hits	1031	Shared Neighborhood Hits	86
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

MDM2_MOUSE
NC score	0.032415 (rank : 172)	θ value	1.06291 (rank : 94)
Query Neighborhood Hits	217	Target Neighborhood Hits	77	Shared Neighborhood Hits	8
SwissProt Accessions	P23804, Q61040, Q64330	Gene names	Mdm2
Domain Architecture
Description	Ubiquitin-protein ligase E3 Mdm2 (EC 6.3.2.-) (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein).

FMN1A_MOUSE
NC score	0.032379 (rank : 173)	θ value	6.88961 (rank : 174)
Query Neighborhood Hits	217	Target Neighborhood Hits	423	Shared Neighborhood Hits	34
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

SI1L3_HUMAN
NC score	0.031885 (rank : 174)	θ value	0.47712 (rank : 74)
Query Neighborhood Hits	217	Target Neighborhood Hits	305	Shared Neighborhood Hits	33
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

CIC_MOUSE
NC score	0.031446 (rank : 175)	θ value	5.27518 (rank : 156)
Query Neighborhood Hits	217	Target Neighborhood Hits	742	Shared Neighborhood Hits	61
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

WASF2_MOUSE
NC score	0.031377 (rank : 176)	θ value	3.0926 (rank : 145)
Query Neighborhood Hits	217	Target Neighborhood Hits	315	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

DIAP1_HUMAN
NC score	0.030948 (rank : 177)	θ value	2.36792 (rank : 117)
Query Neighborhood Hits	217	Target Neighborhood Hits	784	Shared Neighborhood Hits	43
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

ZN750_MOUSE
NC score	0.030759 (rank : 178)	θ value	8.99809 (rank : 217)
Query Neighborhood Hits	217	Target Neighborhood Hits	346	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

SF01_HUMAN
NC score	0.030703 (rank : 179)	θ value	6.88961 (rank : 186)
Query Neighborhood Hits	217	Target Neighborhood Hits	287	Shared Neighborhood Hits	30
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

SF01_MOUSE
NC score	0.030494 (rank : 180)	θ value	6.88961 (rank : 187)
Query Neighborhood Hits	217	Target Neighborhood Hits	240	Shared Neighborhood Hits	28
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

TS13_MOUSE
NC score	0.030359 (rank : 181)	θ value	8.99809 (rank : 213)
Query Neighborhood Hits	217	Target Neighborhood Hits	191	Shared Neighborhood Hits	22
SwissProt Accessions	Q01755	Gene names	Tcp11
Domain Architecture
Description	Testis-specific protein PBS13.

PI5PA_MOUSE
NC score	0.029416 (rank : 182)	θ value	1.06291 (rank : 96)
Query Neighborhood Hits	217	Target Neighborhood Hits	331	Shared Neighborhood Hits	34
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PHC2_MOUSE
NC score	0.029380 (rank : 183)	θ value	0.47712 (rank : 73)
Query Neighborhood Hits	217	Target Neighborhood Hits	156	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QWH1, O88463, Q8K5D9	Gene names	Phc2, Edr2, Ph2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (mPH2) (Early development regulatory protein 2) (p36).

CD5R2_MOUSE
NC score	0.029108 (rank : 184)	θ value	3.0926 (rank : 132)
Query Neighborhood Hits	217	Target Neighborhood Hits	57	Shared Neighborhood Hits	13
SwissProt Accessions	O35926, O35277	Gene names	Cdk5r2, Nck5ai
Domain Architecture
Description	Cyclin-dependent kinase 5 activator 2 precursor (CDK5 activator 2) (Cyclin-dependent kinase 5 regulatory subunit 2) (P39) (P39I).

DIAP1_MOUSE
NC score	0.028755 (rank : 185)	θ value	1.38821 (rank : 101)
Query Neighborhood Hits	217	Target Neighborhood Hits	839	Shared Neighborhood Hits	38
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

FBXW5_MOUSE
NC score	0.028443 (rank : 186)	θ value	8.99809 (rank : 194)
Query Neighborhood Hits	217	Target Neighborhood Hits	159	Shared Neighborhood Hits	22
SwissProt Accessions	Q9QXW2	Gene names	Fbxw5, Fbw5
Domain Architecture
Description	F-box/WD repeat protein 5 (F-box and WD-40 domain protein 5).

3BP1_HUMAN
NC score	0.027966 (rank : 187)	θ value	0.279714 (rank : 58)
Query Neighborhood Hits	217	Target Neighborhood Hits	376	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

K1045_MOUSE
NC score	0.027929 (rank : 188)	θ value	8.99809 (rank : 200)
Query Neighborhood Hits	217	Target Neighborhood Hits	15	Shared Neighborhood Hits	5
SwissProt Accessions	Q80TL4, Q8BH08	Gene names	Kiaa1045
Domain Architecture	No domain graphic available
Description	Protein KIAA1045.

FBXW5_HUMAN
NC score	0.027890 (rank : 189)	θ value	8.99809 (rank : 193)
Query Neighborhood Hits	217	Target Neighborhood Hits	156	Shared Neighborhood Hits	21
SwissProt Accessions	Q969U6, Q5SPZ8, Q5SPZ9, Q5SQ02, Q5SQ03, Q5SQ04, Q8WY79, Q96GJ6, Q9BSU8, Q9H6A8, Q9HBQ6, Q9NSZ3	Gene names	FBXW5, FBW5
Domain Architecture
Description	F-box/WD repeat protein 5 (F-box and WD-40 domain protein 5).

FBW1B_HUMAN
NC score	0.027246 (rank : 190)	θ value	1.81305 (rank : 107)
Query Neighborhood Hits	217	Target Neighborhood Hits	327	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UKB1, Q9P2S8, Q9P2S9, Q9Y4C6	Gene names	FBXW11, BTRCP2, FBW1B, FBXW1B, KIAA0696
Domain Architecture
Description	F-box/WD repeat protein 11 (F-box/WD repeat protein 1B) (F-box and WD repeats protein beta-TrCP2).

TACC2_MOUSE
NC score	0.026077 (rank : 191)	θ value	8.99809 (rank : 212)
Query Neighborhood Hits	217	Target Neighborhood Hits	774	Shared Neighborhood Hits	35
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

FHOD1_MOUSE
NC score	0.025990 (rank : 192)	θ value	8.99809 (rank : 195)
Query Neighborhood Hits	217	Target Neighborhood Hits	217	Shared Neighborhood Hits	28
SwissProt Accessions	Q6P9Q4, Q8BMK2	Gene names	Fhod1, Fhos1
Domain Architecture	No domain graphic available
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

SFPQ_HUMAN
NC score	0.025696 (rank : 193)	θ value	8.99809 (rank : 210)
Query Neighborhood Hits	217	Target Neighborhood Hits	986	Shared Neighborhood Hits	54
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

RBM22_HUMAN
NC score	0.025542 (rank : 194)	θ value	2.36792 (rank : 121)
Query Neighborhood Hits	217	Target Neighborhood Hits	189	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NW64, O95607	Gene names	RBM22
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor RBM22 (RNA-binding motif protein 22).

RBM22_MOUSE
NC score	0.025542 (rank : 195)	θ value	2.36792 (rank : 122)
Query Neighborhood Hits	217	Target Neighborhood Hits	189	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BHS3, Q3TJB0, Q9CXA0	Gene names	Rbm22
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor RBM22 (RNA-binding motif protein 22).

SMRC1_HUMAN
NC score	0.024761 (rank : 196)	θ value	1.81305 (rank : 109)
Query Neighborhood Hits	217	Target Neighborhood Hits	375	Shared Neighborhood Hits	26
SwissProt Accessions	Q92922, Q6P172, Q8IWH2	Gene names	SMARCC1, BAF155
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155).

WASF1_MOUSE
NC score	0.024456 (rank : 197)	θ value	5.27518 (rank : 170)
Query Neighborhood Hits	217	Target Neighborhood Hits	261	Shared Neighborhood Hits	25
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

ENAH_HUMAN
NC score	0.023602 (rank : 198)	θ value	8.99809 (rank : 192)
Query Neighborhood Hits	217	Target Neighborhood Hits	784	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

AB1IP_HUMAN
NC score	0.023513 (rank : 199)	θ value	3.0926 (rank : 130)
Query Neighborhood Hits	217	Target Neighborhood Hits	213	Shared Neighborhood Hits	23
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

ATX2_HUMAN
NC score	0.023479 (rank : 200)	θ value	5.27518 (rank : 154)
Query Neighborhood Hits	217	Target Neighborhood Hits	375	Shared Neighborhood Hits	31
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

APS_HUMAN
NC score	0.022348 (rank : 201)	θ value	2.36792 (rank : 111)
Query Neighborhood Hits	217	Target Neighborhood Hits	162	Shared Neighborhood Hits	6
SwissProt Accessions	O14492	Gene names	APS
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

DCR1A_MOUSE
NC score	0.022092 (rank : 202)	θ value	3.0926 (rank : 134)
Query Neighborhood Hits	217	Target Neighborhood Hits	59	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JIC3, Q571H5, Q6GQR6	Gene names	Dclre1a, Kiaa0086, Snm1, Snm1a
Domain Architecture	No domain graphic available
Description	DNA cross-link repair 1A protein.

FBLI1_HUMAN
NC score	0.021737 (rank : 203)	θ value	5.27518 (rank : 158)
Query Neighborhood Hits	217	Target Neighborhood Hits	200	Shared Neighborhood Hits	14
SwissProt Accessions	Q8WUP2, Q5VVE0, Q5VVE1, Q8IX23, Q96T00, Q9UFD6	Gene names	FBLIM1, FBLP1
Domain Architecture
Description	Filamin-binding LIM protein 1 (Filamin-binding LIM protein 1) (FBLP-1) (Mitogen-inducible 2-interacting protein) (MIG2-interacting protein) (Migfilin).

SHAN1_HUMAN
NC score	0.020973 (rank : 204)	θ value	1.81305 (rank : 108)
Query Neighborhood Hits	217	Target Neighborhood Hits	1041	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

DOCK4_HUMAN
NC score	0.020675 (rank : 205)	θ value	3.0926 (rank : 135)
Query Neighborhood Hits	217	Target Neighborhood Hits	237	Shared Neighborhood Hits	31
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

OBSCN_HUMAN
NC score	0.020389 (rank : 206)	θ value	0.00390308 (rank : 34)
Query Neighborhood Hits	217	Target Neighborhood Hits	1931	Shared Neighborhood Hits	67
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

ALMS1_MOUSE
NC score	0.020030 (rank : 207)	θ value	5.27518 (rank : 153)
Query Neighborhood Hits	217	Target Neighborhood Hits	181	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K4E0, Q6A084, Q8C9N9	Gene names	Alms1, Kiaa0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1 homolog.

PDZD2_HUMAN
NC score	0.020008 (rank : 208)	θ value	8.99809 (rank : 206)
Query Neighborhood Hits	217	Target Neighborhood Hits	772	Shared Neighborhood Hits	45
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

DOCK4_MOUSE
NC score	0.019819 (rank : 209)	θ value	3.0926 (rank : 136)
Query Neighborhood Hits	217	Target Neighborhood Hits	210	Shared Neighborhood Hits	25
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

GA2L3_HUMAN
NC score	0.019769 (rank : 210)	θ value	5.27518 (rank : 161)
Query Neighborhood Hits	217	Target Neighborhood Hits	189	Shared Neighborhood Hits	14
SwissProt Accessions	Q86XJ1	Gene names	GAS2L3
Domain Architecture	No domain graphic available
Description	GAS2-like protein 3 (Growth arrest-specific 2-like 3).

TGIF_HUMAN
NC score	0.019298 (rank : 211)	θ value	2.36792 (rank : 124)
Query Neighborhood Hits	217	Target Neighborhood Hits	109	Shared Neighborhood Hits	4
SwissProt Accessions	Q15583, Q6ICR0, Q8N5X9, Q9NRS0	Gene names	TGIF
Domain Architecture
Description	5'-TG-3'-interacting factor (Homeobox protein TGIF).

NFAC1_HUMAN
NC score	0.017485 (rank : 212)	θ value	8.99809 (rank : 205)
Query Neighborhood Hits	217	Target Neighborhood Hits	312	Shared Neighborhood Hits	44
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

TITIN_HUMAN
NC score	0.016660 (rank : 213)	θ value	0.0563607 (rank : 44)
Query Neighborhood Hits	217	Target Neighborhood Hits	2923	Shared Neighborhood Hits	74
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

GP178_HUMAN
NC score	0.016490 (rank : 214)	θ value	8.99809 (rank : 196)
Query Neighborhood Hits	217	Target Neighborhood Hits	25	Shared Neighborhood Hits	6
SwissProt Accessions	Q9P2C4, Q5VTU1	Gene names	GPR178, KIAA1423
Domain Architecture	No domain graphic available
Description	Integral membrane protein GPR178.

HES7_MOUSE
NC score	0.016489 (rank : 215)	θ value	8.99809 (rank : 197)
Query Neighborhood Hits	217	Target Neighborhood Hits	72	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BKT2, Q99JA6	Gene names	Hes7
Domain Architecture	No domain graphic available
Description	Transcription factor HES-7 (Hairy and enhancer of split 7) (bHLH factor Hes7).

DAG1_HUMAN
NC score	0.016120 (rank : 216)	θ value	5.27518 (rank : 157)
Query Neighborhood Hits	217	Target Neighborhood Hits	104	Shared Neighborhood Hits	13
SwissProt Accessions	Q14118	Gene names	DAG1
Domain Architecture
Description	Dystroglycan precursor (Dystrophin-associated glycoprotein 1) [Contains: Alpha-dystroglycan (Alpha-DG); Beta-dystroglycan (Beta- DG)].

MYCB2_MOUSE
NC score	0.015477 (rank : 217)	θ value	5.27518 (rank : 164)
Query Neighborhood Hits	217	Target Neighborhood Hits	307	Shared Neighborhood Hits	12
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

ZCHC3_HUMAN
NC score	0.014896 (rank : 218)	θ value	8.99809 (rank : 216)
Query Neighborhood Hits	217	Target Neighborhood Hits	53	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NUD5, Q6NT79	Gene names	ZCCHC3, C20orf99
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 3.

CO4A4_HUMAN
NC score	0.014693 (rank : 219)	θ value	3.0926 (rank : 133)
Query Neighborhood Hits	217	Target Neighborhood Hits	440	Shared Neighborhood Hits	37
SwissProt Accessions	P53420	Gene names	COL4A4
Domain Architecture
Description	Collagen alpha-4(IV) chain precursor.

RFIP1_MOUSE
NC score	0.013231 (rank : 220)	θ value	6.88961 (rank : 185)
Query Neighborhood Hits	217	Target Neighborhood Hits	152	Shared Neighborhood Hits	10
SwissProt Accessions	Q9D620, Q3UBC2, Q8BN24	Gene names	Rab11fip1, Rcp
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

SF3B4_HUMAN
NC score	0.013007 (rank : 221)	θ value	6.88961 (rank : 188)
Query Neighborhood Hits	217	Target Neighborhood Hits	445	Shared Neighborhood Hits	28
SwissProt Accessions	Q15427	Gene names	SF3B4, SAP49
Domain Architecture
Description	Splicing factor 3B subunit 4 (Spliceosome-associated protein 49) (SAP 49) (SF3b50) (Pre-mRNA-splicing factor SF3b 49 kDa subunit).

RYR1_HUMAN
NC score	0.012636 (rank : 222)	θ value	8.99809 (rank : 209)
Query Neighborhood Hits	217	Target Neighborhood Hits	303	Shared Neighborhood Hits	16
SwissProt Accessions	P21817, Q16314, Q16368, Q9NPK1, Q9P1U4	Gene names	RYR1, RYDR
Domain Architecture
Description	Ryanodine receptor 1 (Skeletal muscle-type ryanodine receptor) (RyR1) (RYR-1) (Skeletal muscle calcium release channel).

VINC_HUMAN
NC score	0.012495 (rank : 223)	θ value	8.99809 (rank : 214)
Query Neighborhood Hits	217	Target Neighborhood Hits	145	Shared Neighborhood Hits	9
SwissProt Accessions	P18206, Q16450, Q5SWX2, Q7Z3B8, Q8IXU7	Gene names	VCL
Domain Architecture
Description	Vinculin (Metavinculin).

FOG1_MOUSE
NC score	0.011991 (rank : 224)	θ value	0.62314 (rank : 78)
Query Neighborhood Hits	217	Target Neighborhood Hits	1237	Shared Neighborhood Hits	66
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

PDE3A_MOUSE
NC score	0.011718 (rank : 225)	θ value	6.88961 (rank : 182)
Query Neighborhood Hits	217	Target Neighborhood Hits	115	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z0X4	Gene names	Pde3a
Domain Architecture
Description	cGMP-inhibited 3',5'-cyclic phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A).

K0562_MOUSE
NC score	0.011569 (rank : 226)	θ value	8.99809 (rank : 199)
Query Neighborhood Hits	217	Target Neighborhood Hits	86	Shared Neighborhood Hits	8
SwissProt Accessions	Q80V31, Q6ZQ95	Gene names	Kiaa0562
Domain Architecture	No domain graphic available
Description	Protein KIAA0562.

VINC_MOUSE
NC score	0.011265 (rank : 227)	θ value	8.99809 (rank : 215)
Query Neighborhood Hits	217	Target Neighborhood Hits	135	Shared Neighborhood Hits	9
SwissProt Accessions	Q64727, Q8BP32, Q8BS46, Q922C5, Q922D9	Gene names	Vcl
Domain Architecture
Description	Vinculin (Metavinculin).

XYLT1_HUMAN
NC score	0.011261 (rank : 228)	θ value	5.27518 (rank : 171)
Query Neighborhood Hits	217	Target Neighborhood Hits	87	Shared Neighborhood Hits	8
SwissProt Accessions	Q86Y38, Q9H1B6	Gene names	XYLT1, XT1
Domain Architecture	No domain graphic available
Description	Xylosyltransferase 1 (EC 2.4.2.26) (Xylosyltransferase I) (XylT-I) (XT-I) (Peptide O-xylosyltransferase 1).

SEM6C_HUMAN
NC score	0.009890 (rank : 229)	θ value	0.813845 (rank : 87)
Query Neighborhood Hits	217	Target Neighborhood Hits	117	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H3T2, Q5JR71, Q8WXT8, Q8WXT9, Q8WXU0, Q96JF8	Gene names	SEMA6C, KIAA1869, SEMAY
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

POLH_MOUSE
NC score	0.009555 (rank : 230)	θ value	6.88961 (rank : 184)
Query Neighborhood Hits	217	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JJN0, Q9JJJ2	Gene names	Polh, Rad30a, Xpv
Domain Architecture	No domain graphic available
Description	DNA polymerase eta (EC 2.7.7.7) (RAD30 homolog A) (Xeroderma pigmentosum variant type protein homolog).

NEDD4_MOUSE
NC score	0.007840 (rank : 231)	θ value	3.0926 (rank : 141)
Query Neighborhood Hits	217	Target Neighborhood Hits	212	Shared Neighborhood Hits	4
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

PDE3A_HUMAN
NC score	0.007494 (rank : 232)	θ value	6.88961 (rank : 181)
Query Neighborhood Hits	217	Target Neighborhood Hits	79	Shared Neighborhood Hits	4
SwissProt Accessions	Q14432, O60865, Q13348	Gene names	PDE3A
Domain Architecture
Description	cGMP-inhibited 3',5'-cyclic phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A).

KCNC3_HUMAN
NC score	0.007311 (rank : 233)	θ value	8.99809 (rank : 201)
Query Neighborhood Hits	217	Target Neighborhood Hits	256	Shared Neighborhood Hits	29
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

EGLN2_HUMAN
NC score	0.007058 (rank : 234)	θ value	8.99809 (rank : 191)
Query Neighborhood Hits	217	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q96KS0, Q8WWY4, Q9BV14	Gene names	EGLN2, EIT6
Domain Architecture
Description	Egl nine homolog 2 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 1) (HIF-prolyl hydroxylase 1) (HIF-PH1) (HPH-3) (Prolyl hydroxylase domain-containing protein 1) (PHD1) (Estrogen-induced tag 6).

RX_HUMAN
NC score	0.007013 (rank : 235)	θ value	0.813845 (rank : 86)
Query Neighborhood Hits	217	Target Neighborhood Hits	423	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y2V3	Gene names	RAX, RX
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

CF182_MOUSE
NC score	0.006770 (rank : 236)	θ value	8.99809 (rank : 190)
Query Neighborhood Hits	217	Target Neighborhood Hits	551	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VDS7, Q9CZE0, Q9D5A1	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf182 homolog.

PAK4_MOUSE
NC score	0.005966 (rank : 237)	θ value	1.06291 (rank : 95)
Query Neighborhood Hits	217	Target Neighborhood Hits	1098	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

PAK4_HUMAN
NC score	0.005958 (rank : 238)	θ value	0.0563607 (rank : 41)
Query Neighborhood Hits	217	Target Neighborhood Hits	924	Shared Neighborhood Hits	15
SwissProt Accessions	O96013, Q8N4E1, Q8NCH5, Q8NDE3, Q9BU33, Q9ULS8	Gene names	PAK4, KIAA1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

HXB4_HUMAN
NC score	0.005720 (rank : 239)	θ value	6.88961 (rank : 178)
Query Neighborhood Hits	217	Target Neighborhood Hits	376	Shared Neighborhood Hits	16
SwissProt Accessions	P17483, Q9NTA0	Gene names	HOXB4, HOX2F
Domain Architecture
Description	Homeobox protein Hox-B4 (Hox-2F) (Hox-2.6).

RXRB_MOUSE
NC score	0.005474 (rank : 240)	θ value	5.27518 (rank : 167)
Query Neighborhood Hits	217	Target Neighborhood Hits	230	Shared Neighborhood Hits	19
SwissProt Accessions	P28704, P33243	Gene names	Rxrb, Nr2b2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta) (MHC class I regulatory element-binding protein H-2RIIBP).

LTBP4_MOUSE
NC score	0.004676 (rank : 241)	θ value	8.99809 (rank : 202)
Query Neighborhood Hits	217	Target Neighborhood Hits	607	Shared Neighborhood Hits	28
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

SREC2_HUMAN
NC score	0.004334 (rank : 242)	θ value	8.99809 (rank : 211)
Query Neighborhood Hits	217	Target Neighborhood Hits	645	Shared Neighborhood Hits	25
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

ULK1_HUMAN
NC score	0.003343 (rank : 243)	θ value	5.27518 (rank : 169)
Query Neighborhood Hits	217	Target Neighborhood Hits	1121	Shared Neighborhood Hits	42
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).

HXB4_MOUSE
NC score	0.003181 (rank : 244)	θ value	6.88961 (rank : 179)
Query Neighborhood Hits	217	Target Neighborhood Hits	375	Shared Neighborhood Hits	13
SwissProt Accessions	P10284, Q3UZB4, Q4VBG0	Gene names	Hoxb4, Hox-2.6, Hoxb-4
Domain Architecture
Description	Homeobox protein Hox-B4 (Hox-2.6).

ACRO_HUMAN
NC score	0.002933 (rank : 245)	θ value	2.36792 (rank : 110)
Query Neighborhood Hits	217	Target Neighborhood Hits	291	Shared Neighborhood Hits	15
SwissProt Accessions	P10323, Q6ICK2	Gene names	ACR, ACRS
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

LAP4_MOUSE
NC score	0.002338 (rank : 246)	θ value	5.27518 (rank : 162)
Query Neighborhood Hits	217	Target Neighborhood Hits	590	Shared Neighborhood Hits	15
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

M3K10_HUMAN
NC score	-0.000196 (rank : 247)	θ value	5.27518 (rank : 163)
Query Neighborhood Hits	217	Target Neighborhood Hits	1071	Shared Neighborhood Hits	15
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).