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Network neighborhood for query Sequence : FA47A_HUMAN

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FA47A_HUMAN
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

FA47A_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	451	Target Neighborhood Hits	451	Shared Neighborhood Hits	451
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

FA47B_HUMAN
θ value	0 (rank : 2)	NC score	0.819209 (rank : 2)
Query Neighborhood Hits	451	Target Neighborhood Hits	431	Shared Neighborhood Hits	215
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

SRRM1_HUMAN
θ value	3.64472e-09 (rank : 3)	NC score	0.323403 (rank : 7)
Query Neighborhood Hits	451	Target Neighborhood Hits	690	Shared Neighborhood Hits	129
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

IWS1_HUMAN
θ value	3.08544e-08 (rank : 4)	NC score	0.246085 (rank : 28)
Query Neighborhood Hits	451	Target Neighborhood Hits	1241	Shared Neighborhood Hits	155
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

PRG4_HUMAN
θ value	4.0297e-08 (rank : 5)	NC score	0.259870 (rank : 18)
Query Neighborhood Hits	451	Target Neighborhood Hits	764	Shared Neighborhood Hits	116
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRG4_MOUSE
θ value	1.17247e-07 (rank : 6)	NC score	0.246096 (rank : 27)
Query Neighborhood Hits	451	Target Neighborhood Hits	624	Shared Neighborhood Hits	100
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SRRM1_MOUSE
θ value	1.99992e-07 (rank : 7)	NC score	0.356752 (rank : 3)
Query Neighborhood Hits	451	Target Neighborhood Hits	966	Shared Neighborhood Hits	205
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

IWS1_MOUSE
θ value	3.41135e-07 (rank : 8)	NC score	0.252042 (rank : 22)
Query Neighborhood Hits	451	Target Neighborhood Hits	1258	Shared Neighborhood Hits	175
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MLL2_HUMAN
θ value	4.45536e-07 (rank : 9)	NC score	0.202481 (rank : 58)
Query Neighborhood Hits	451	Target Neighborhood Hits	1788	Shared Neighborhood Hits	210
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MUC2_HUMAN
θ value	5.81887e-07 (rank : 10)	NC score	0.172254 (rank : 92)
Query Neighborhood Hits	451	Target Neighborhood Hits	906	Shared Neighborhood Hits	110
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

SON_HUMAN
θ value	5.81887e-07 (rank : 11)	NC score	0.342561 (rank : 4)
Query Neighborhood Hits	451	Target Neighborhood Hits	1568	Shared Neighborhood Hits	275
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

DIAP1_MOUSE
θ value	2.88788e-06 (rank : 12)	NC score	0.200089 (rank : 62)
Query Neighborhood Hits	451	Target Neighborhood Hits	839	Shared Neighborhood Hits	87
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

RAPH1_HUMAN
θ value	3.77169e-06 (rank : 13)	NC score	0.240292 (rank : 33)
Query Neighborhood Hits	451	Target Neighborhood Hits	593	Shared Neighborhood Hits	129
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

SRRM2_HUMAN
θ value	1.43324e-05 (rank : 14)	NC score	0.253825 (rank : 20)
Query Neighborhood Hits	451	Target Neighborhood Hits	1296	Shared Neighborhood Hits	194
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

ESX1L_HUMAN
θ value	4.1701e-05 (rank : 15)	NC score	0.088642 (rank : 331)
Query Neighborhood Hits	451	Target Neighborhood Hits	498	Shared Neighborhood Hits	52
SwissProt Accessions	Q8N693, Q7Z6K7	Gene names	ESX1L, ESX1R
Domain Architecture
Description	Extraembryonic, spermatogenesis, homeobox 1-like protein.

NACAM_MOUSE
θ value	5.44631e-05 (rank : 16)	NC score	0.330856 (rank : 6)
Query Neighborhood Hits	451	Target Neighborhood Hits	1866	Shared Neighborhood Hits	290
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

WASIP_HUMAN
θ value	7.1131e-05 (rank : 17)	NC score	0.280700 (rank : 10)
Query Neighborhood Hits	451	Target Neighborhood Hits	458	Shared Neighborhood Hits	99
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

BRD4_HUMAN
θ value	9.29e-05 (rank : 18)	NC score	0.171524 (rank : 97)
Query Neighborhood Hits	451	Target Neighborhood Hits	851	Shared Neighborhood Hits	134
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

CSKI1_HUMAN
θ value	9.29e-05 (rank : 19)	NC score	0.110992 (rank : 228)
Query Neighborhood Hits	451	Target Neighborhood Hits	997	Shared Neighborhood Hits	148
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

MAGC1_HUMAN
θ value	9.29e-05 (rank : 20)	NC score	0.095347 (rank : 300)
Query Neighborhood Hits	451	Target Neighborhood Hits	431	Shared Neighborhood Hits	81
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

SON_MOUSE
θ value	9.29e-05 (rank : 21)	NC score	0.294361 (rank : 9)
Query Neighborhood Hits	451	Target Neighborhood Hits	957	Shared Neighborhood Hits	189
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

CEL_HUMAN
θ value	0.000121331 (rank : 22)	NC score	0.237389 (rank : 38)
Query Neighborhood Hits	451	Target Neighborhood Hits	896	Shared Neighborhood Hits	213
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

TXND2_HUMAN
θ value	0.000121331 (rank : 23)	NC score	0.269274 (rank : 14)
Query Neighborhood Hits	451	Target Neighborhood Hits	793	Shared Neighborhood Hits	157
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

DIAP1_HUMAN
θ value	0.000158464 (rank : 24)	NC score	0.194649 (rank : 71)
Query Neighborhood Hits	451	Target Neighborhood Hits	784	Shared Neighborhood Hits	92
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

MAP1B_HUMAN
θ value	0.00020696 (rank : 25)	NC score	0.215079 (rank : 47)
Query Neighborhood Hits	451	Target Neighborhood Hits	903	Shared Neighborhood Hits	123
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

MYPN_HUMAN
θ value	0.00020696 (rank : 26)	NC score	0.066573 (rank : 482)
Query Neighborhood Hits	451	Target Neighborhood Hits	418	Shared Neighborhood Hits	36
SwissProt Accessions	Q86TC9, Q5VV35, Q5VV36, Q86T37, Q8N3L4, Q96K90, Q96KF5	Gene names	MYPN, MYOP
Domain Architecture	No domain graphic available
Description	Myopalladin (145 kDa sarcomeric protein).

NFH_MOUSE
θ value	0.00020696 (rank : 27)	NC score	0.203068 (rank : 56)
Query Neighborhood Hits	451	Target Neighborhood Hits	2247	Shared Neighborhood Hits	266
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

TARSH_HUMAN
θ value	0.00020696 (rank : 28)	NC score	0.340602 (rank : 5)
Query Neighborhood Hits	451	Target Neighborhood Hits	768	Shared Neighborhood Hits	196
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

FMN2_HUMAN
θ value	0.000270298 (rank : 29)	NC score	0.239335 (rank : 36)
Query Neighborhood Hits	451	Target Neighborhood Hits	484	Shared Neighborhood Hits	97
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

WASIP_MOUSE
θ value	0.000270298 (rank : 30)	NC score	0.264910 (rank : 15)
Query Neighborhood Hits	451	Target Neighborhood Hits	392	Shared Neighborhood Hits	93
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

IF4G1_HUMAN
θ value	0.00035302 (rank : 31)	NC score	0.110502 (rank : 229)
Query Neighborhood Hits	451	Target Neighborhood Hits	347	Shared Neighborhood Hits	69
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

BRD4_MOUSE
θ value	0.000461057 (rank : 32)	NC score	0.162168 (rank : 116)
Query Neighborhood Hits	451	Target Neighborhood Hits	845	Shared Neighborhood Hits	127
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

FMN1A_MOUSE
θ value	0.000461057 (rank : 33)	NC score	0.247152 (rank : 24)
Query Neighborhood Hits	451	Target Neighborhood Hits	423	Shared Neighborhood Hits	98
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

FMN1B_MOUSE
θ value	0.000461057 (rank : 34)	NC score	0.244883 (rank : 30)
Query Neighborhood Hits	451	Target Neighborhood Hits	447	Shared Neighborhood Hits	99
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

ATN1_HUMAN
θ value	0.000602161 (rank : 35)	NC score	0.214115 (rank : 49)
Query Neighborhood Hits	451	Target Neighborhood Hits	676	Shared Neighborhood Hits	108
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

NFH_HUMAN
θ value	0.000602161 (rank : 36)	NC score	0.093250 (rank : 310)
Query Neighborhood Hits	451	Target Neighborhood Hits	1242	Shared Neighborhood Hits	110
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

MAP1A_HUMAN
θ value	0.000786445 (rank : 37)	NC score	0.195018 (rank : 70)
Query Neighborhood Hits	451	Target Neighborhood Hits	1626	Shared Neighborhood Hits	225
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MYO15_HUMAN
θ value	0.000786445 (rank : 38)	NC score	0.096103 (rank : 296)
Query Neighborhood Hits	451	Target Neighborhood Hits	671	Shared Neighborhood Hits	181
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

RIN3_MOUSE
θ value	0.000786445 (rank : 39)	NC score	0.171743 (rank : 94)
Query Neighborhood Hits	451	Target Neighborhood Hits	239	Shared Neighborhood Hits	67
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

SRRM2_MOUSE
θ value	0.000786445 (rank : 40)	NC score	0.273090 (rank : 11)
Query Neighborhood Hits	451	Target Neighborhood Hits	1470	Shared Neighborhood Hits	219
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

CN155_HUMAN
θ value	0.00102713 (rank : 41)	NC score	0.245912 (rank : 29)
Query Neighborhood Hits	451	Target Neighborhood Hits	385	Shared Neighborhood Hits	80
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

DGKK_HUMAN
θ value	0.00102713 (rank : 42)	NC score	0.147730 (rank : 140)
Query Neighborhood Hits	451	Target Neighborhood Hits	378	Shared Neighborhood Hits	59
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

K1802_MOUSE
θ value	0.00102713 (rank : 43)	NC score	0.252487 (rank : 21)
Query Neighborhood Hits	451	Target Neighborhood Hits	1596	Shared Neighborhood Hits	249
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

OGFR_MOUSE
θ value	0.00102713 (rank : 44)	NC score	0.213081 (rank : 50)
Query Neighborhood Hits	451	Target Neighborhood Hits	584	Shared Neighborhood Hits	113
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

PCLO_HUMAN
θ value	0.00134147 (rank : 45)	NC score	0.246521 (rank : 26)
Query Neighborhood Hits	451	Target Neighborhood Hits	2046	Shared Neighborhood Hits	294
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

ARHG7_HUMAN
θ value	0.00175202 (rank : 46)	NC score	0.054603 (rank : 617)
Query Neighborhood Hits	451	Target Neighborhood Hits	347	Shared Neighborhood Hits	21
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

BSN_HUMAN
θ value	0.00175202 (rank : 47)	NC score	0.195476 (rank : 69)
Query Neighborhood Hits	451	Target Neighborhood Hits	1537	Shared Neighborhood Hits	202
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CSKI1_MOUSE
θ value	0.00228821 (rank : 48)	NC score	0.121022 (rank : 203)
Query Neighborhood Hits	451	Target Neighborhood Hits	1031	Shared Neighborhood Hits	185
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

MUC5B_HUMAN
θ value	0.00228821 (rank : 49)	NC score	0.124940 (rank : 189)
Query Neighborhood Hits	451	Target Neighborhood Hits	1020	Shared Neighborhood Hits	88
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

NOLC1_HUMAN
θ value	0.00298849 (rank : 50)	NC score	0.165782 (rank : 113)
Query Neighborhood Hits	451	Target Neighborhood Hits	452	Shared Neighborhood Hits	64
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

SYNJ1_HUMAN
θ value	0.00298849 (rank : 51)	NC score	0.167869 (rank : 108)
Query Neighborhood Hits	451	Target Neighborhood Hits	498	Shared Neighborhood Hits	131
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

AFF1_MOUSE
θ value	0.00390308 (rank : 52)	NC score	0.151672 (rank : 130)
Query Neighborhood Hits	451	Target Neighborhood Hits	351	Shared Neighborhood Hits	65
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

FMN2_MOUSE
θ value	0.00390308 (rank : 53)	NC score	0.242987 (rank : 31)
Query Neighborhood Hits	451	Target Neighborhood Hits	349	Shared Neighborhood Hits	101
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

PRR12_HUMAN
θ value	0.00390308 (rank : 54)	NC score	0.262651 (rank : 16)
Query Neighborhood Hits	451	Target Neighborhood Hits	460	Shared Neighborhood Hits	103
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

CABIN_HUMAN
θ value	0.00509761 (rank : 55)	NC score	0.200101 (rank : 61)
Query Neighborhood Hits	451	Target Neighborhood Hits	490	Shared Neighborhood Hits	117
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

RIMS2_HUMAN
θ value	0.00509761 (rank : 56)	NC score	0.089609 (rank : 326)
Query Neighborhood Hits	451	Target Neighborhood Hits	342	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

CCNK_MOUSE
θ value	0.00665767 (rank : 57)	NC score	0.148864 (rank : 134)
Query Neighborhood Hits	451	Target Neighborhood Hits	350	Shared Neighborhood Hits	80
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

ARHG7_MOUSE
θ value	0.00869519 (rank : 58)	NC score	0.052837 (rank : 644)
Query Neighborhood Hits	451	Target Neighborhood Hits	396	Shared Neighborhood Hits	20
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

MAP1B_MOUSE
θ value	0.00869519 (rank : 59)	NC score	0.190941 (rank : 75)
Query Neighborhood Hits	451	Target Neighborhood Hits	977	Shared Neighborhood Hits	123
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

MBD6_HUMAN
θ value	0.00869519 (rank : 60)	NC score	0.186748 (rank : 77)
Query Neighborhood Hits	451	Target Neighborhood Hits	349	Shared Neighborhood Hits	74
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

MLL4_HUMAN
θ value	0.00869519 (rank : 61)	NC score	0.174877 (rank : 90)
Query Neighborhood Hits	451	Target Neighborhood Hits	722	Shared Neighborhood Hits	137
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

PI5PA_HUMAN
θ value	0.00869519 (rank : 62)	NC score	0.197683 (rank : 66)
Query Neighborhood Hits	451	Target Neighborhood Hits	749	Shared Neighborhood Hits	174
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

UBP36_HUMAN
θ value	0.00869519 (rank : 63)	NC score	0.068818 (rank : 458)
Query Neighborhood Hits	451	Target Neighborhood Hits	232	Shared Neighborhood Hits	46
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

WASL_MOUSE
θ value	0.00869519 (rank : 64)	NC score	0.240104 (rank : 34)
Query Neighborhood Hits	451	Target Neighborhood Hits	339	Shared Neighborhood Hits	85
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WBP11_HUMAN
θ value	0.00869519 (rank : 65)	NC score	0.213053 (rank : 51)
Query Neighborhood Hits	451	Target Neighborhood Hits	354	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

WBP11_MOUSE
θ value	0.00869519 (rank : 66)	NC score	0.206763 (rank : 54)
Query Neighborhood Hits	451	Target Neighborhood Hits	362	Shared Neighborhood Hits	76
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

ZN580_MOUSE
θ value	0.0148317 (rank : 67)	NC score	0.018295 (rank : 785)
Query Neighborhood Hits	451	Target Neighborhood Hits	711	Shared Neighborhood Hits	28
SwissProt Accessions	Q9DB38	Gene names	Znf580, Zfp580
Domain Architecture	No domain graphic available
Description	Zinc finger protein 580.

SF3A2_HUMAN
θ value	0.0193708 (rank : 68)	NC score	0.199316 (rank : 64)
Query Neighborhood Hits	451	Target Neighborhood Hits	263	Shared Neighborhood Hits	59
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SF3A2_MOUSE
θ value	0.0193708 (rank : 69)	NC score	0.202401 (rank : 59)
Query Neighborhood Hits	451	Target Neighborhood Hits	247	Shared Neighborhood Hits	62
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

AMELY_HUMAN
θ value	0.0252991 (rank : 70)	NC score	0.122791 (rank : 195)
Query Neighborhood Hits	451	Target Neighborhood Hits	57	Shared Neighborhood Hits	18
SwissProt Accessions	Q99218, Q6RWT1	Gene names	AMELY, AMGL, AMGY
Domain Architecture
Description	Amelogenin, Y isoform precursor.

AB1IP_MOUSE
θ value	0.0330416 (rank : 71)	NC score	0.154411 (rank : 127)
Query Neighborhood Hits	451	Target Neighborhood Hits	181	Shared Neighborhood Hits	59
SwissProt Accessions	Q8R5A3, O35329, Q8BRU0, Q99KV8	Gene names	Apbb1ip, Prel1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 48).

INCE_HUMAN
θ value	0.0330416 (rank : 72)	NC score	0.057300 (rank : 575)
Query Neighborhood Hits	451	Target Neighborhood Hits	978	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

MAGE1_HUMAN
θ value	0.0330416 (rank : 73)	NC score	0.242315 (rank : 32)
Query Neighborhood Hits	451	Target Neighborhood Hits	1389	Shared Neighborhood Hits	236
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MUC7_HUMAN
θ value	0.0330416 (rank : 74)	NC score	0.214673 (rank : 48)
Query Neighborhood Hits	451	Target Neighborhood Hits	538	Shared Neighborhood Hits	88
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

PC11X_HUMAN
θ value	0.0330416 (rank : 75)	NC score	0.035333 (rank : 720)
Query Neighborhood Hits	451	Target Neighborhood Hits	199	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BZA7, Q2TJH0, Q2TJH1, Q2TJH3, Q5JVZ0, Q70LR8, Q70LS7, Q70LS8, Q70LS9, Q70LT7, Q70LT8, Q70LT9, Q70LU0, Q70LU1, Q96RV4, Q96RW0, Q9BZA6, Q9H4E0, Q9P2M0, Q9P2X5	Gene names	PCDH11X, PCDH11, PCDHX
Domain Architecture	No domain graphic available
Description	Protocadherin-11 X-linked precursor (Protocadherin-11) (Protocadherin on the X chromosome) (PCDH-X) (Protocadherin-S).

REXO1_MOUSE
θ value	0.0330416 (rank : 76)	NC score	0.084297 (rank : 350)
Query Neighborhood Hits	451	Target Neighborhood Hits	166	Shared Neighborhood Hits	41
SwissProt Accessions	Q7TT28, Q3UMP1, Q69ZR0, Q6NSQ6, Q6PI95, Q9DA29	Gene names	Rexo1, Kiaa1138, Tceb3bp1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Transcription elongation factor B polypeptide 3-binding protein 1).

RIMS1_HUMAN
θ value	0.0330416 (rank : 77)	NC score	0.100627 (rank : 273)
Query Neighborhood Hits	451	Target Neighborhood Hits	437	Shared Neighborhood Hits	50
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

SPEG_HUMAN
θ value	0.0330416 (rank : 78)	NC score	0.055245 (rank : 607)
Query Neighborhood Hits	451	Target Neighborhood Hits	1762	Shared Neighborhood Hits	165
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

WASF1_HUMAN
θ value	0.0330416 (rank : 79)	NC score	0.177918 (rank : 86)
Query Neighborhood Hits	451	Target Neighborhood Hits	260	Shared Neighborhood Hits	69
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

5NT1B_MOUSE
θ value	0.0431538 (rank : 80)	NC score	0.072513 (rank : 430)
Query Neighborhood Hits	451	Target Neighborhood Hits	78	Shared Neighborhood Hits	21
SwissProt Accessions	Q91YE9, Q91Y48	Gene names	Nt5c1b, Airp
Domain Architecture
Description	Cytosolic 5'-nucleotidase 1B (EC 3.1.3.5) (Cytosolic 5'-nucleotidase IB) (cN1B) (cN-IB) (Autoimmune infertility-related protein).

ALEX_HUMAN
θ value	0.0431538 (rank : 81)	NC score	0.215762 (rank : 46)
Query Neighborhood Hits	451	Target Neighborhood Hits	361	Shared Neighborhood Hits	100
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

GAK3_HUMAN
θ value	0.0431538 (rank : 82)	NC score	0.109296 (rank : 239)
Query Neighborhood Hits	451	Target Neighborhood Hits	182	Shared Neighborhood Hits	66
SwissProt Accessions	Q9YNA8	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19q12 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(C19) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

OGFR_HUMAN
θ value	0.0431538 (rank : 83)	NC score	0.272128 (rank : 12)
Query Neighborhood Hits	451	Target Neighborhood Hits	1582	Shared Neighborhood Hits	253
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

WASL_HUMAN
θ value	0.0431538 (rank : 84)	NC score	0.222498 (rank : 43)
Query Neighborhood Hits	451	Target Neighborhood Hits	312	Shared Neighborhood Hits	80
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WIRE_MOUSE
θ value	0.0431538 (rank : 85)	NC score	0.200497 (rank : 60)
Query Neighborhood Hits	451	Target Neighborhood Hits	310	Shared Neighborhood Hits	80
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

G3BP_MOUSE
θ value	0.0563607 (rank : 86)	NC score	0.066971 (rank : 476)
Query Neighborhood Hits	451	Target Neighborhood Hits	209	Shared Neighborhood Hits	25
SwissProt Accessions	P97855	Gene names	G3bp, G3bp1
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 1 (EC 3.6.1.-) (ATP- dependent DNA helicase VIII) (GAP SH3-domain-binding protein 1) (G3BP- 1) (HDH-VIII).

LRC56_MOUSE
θ value	0.0563607 (rank : 87)	NC score	0.096247 (rank : 295)
Query Neighborhood Hits	451	Target Neighborhood Hits	100	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K375, Q571F2	Gene names	Lrrc56
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 56.

NCOR2_HUMAN
θ value	0.0563607 (rank : 88)	NC score	0.146156 (rank : 145)
Query Neighborhood Hits	451	Target Neighborhood Hits	870	Shared Neighborhood Hits	136
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

SET1A_HUMAN
θ value	0.0563607 (rank : 89)	NC score	0.170255 (rank : 100)
Query Neighborhood Hits	451	Target Neighborhood Hits	690	Shared Neighborhood Hits	104
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

US6NL_HUMAN
θ value	0.0563607 (rank : 90)	NC score	0.073856 (rank : 418)
Query Neighborhood Hits	451	Target Neighborhood Hits	201	Shared Neighborhood Hits	50
SwissProt Accessions	Q92738, Q15400, Q7L0K9	Gene names	USP6NL, KIAA0019
Domain Architecture	No domain graphic available
Description	USP6 N-terminal-like protein (Related to the N-terminus of tre) (RN- tre).

AFF4_HUMAN
θ value	0.0736092 (rank : 91)	NC score	0.134470 (rank : 167)
Query Neighborhood Hits	451	Target Neighborhood Hits	611	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

BAT2_HUMAN
θ value	0.0736092 (rank : 92)	NC score	0.202755 (rank : 57)
Query Neighborhood Hits	451	Target Neighborhood Hits	931	Shared Neighborhood Hits	180
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

FIBB_MOUSE
θ value	0.0736092 (rank : 93)	NC score	0.031239 (rank : 733)
Query Neighborhood Hits	451	Target Neighborhood Hits	96	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K0E8, Q91ZP1	Gene names	Fgb
Domain Architecture	No domain graphic available
Description	Fibrinogen beta chain precursor [Contains: Fibrinopeptide B].

PC11Y_HUMAN
θ value	0.0736092 (rank : 94)	NC score	0.035456 (rank : 719)
Query Neighborhood Hits	451	Target Neighborhood Hits	205	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BZA8, Q70LR6, Q70LR8, Q70LS0, Q70LS1, Q70LS2, Q70LS3, Q70LS4, Q70LS5, Q8WY34, Q9BZA9, Q9H4E1	Gene names	PCDH11Y, PCDH11, PCDH22, PCDHY
Domain Architecture	No domain graphic available
Description	Protocadherin-11 Y-linked precursor (Protocadherin-11) (Protocadherin- 22) (Protocadherin on the Y chromosome) (PCDH-Y) (Protocadherin prostate cancer) (Protocadherin-PC).

AFF1_HUMAN
θ value	0.0961366 (rank : 95)	NC score	0.164805 (rank : 115)
Query Neighborhood Hits	451	Target Neighborhood Hits	506	Shared Neighborhood Hits	88
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

AMELX_HUMAN
θ value	0.0961366 (rank : 96)	NC score	0.134002 (rank : 169)
Query Neighborhood Hits	451	Target Neighborhood Hits	95	Shared Neighborhood Hits	31
SwissProt Accessions	Q99217, Q96NW6, Q9UCA7	Gene names	AMELX, AMG, AMGX
Domain Architecture
Description	Amelogenin, X isoform precursor.

DIAP2_MOUSE
θ value	0.0961366 (rank : 97)	NC score	0.162028 (rank : 117)
Query Neighborhood Hits	451	Target Neighborhood Hits	260	Shared Neighborhood Hits	57
SwissProt Accessions	O70566, Q8C2G8	Gene names	Diaph2, Diap2
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2) (mDia3).

FR1OP_MOUSE
θ value	0.0961366 (rank : 98)	NC score	0.059557 (rank : 543)
Query Neighborhood Hits	451	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q66JX5, Q32P17, Q8BH91	Gene names	Fgfr1op
Domain Architecture	No domain graphic available
Description	FGFR1 oncogene partner.

RERE_MOUSE
θ value	0.0961366 (rank : 99)	NC score	0.165816 (rank : 112)
Query Neighborhood Hits	451	Target Neighborhood Hits	785	Shared Neighborhood Hits	133
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

TAF3_HUMAN
θ value	0.0961366 (rank : 100)	NC score	0.091509 (rank : 316)
Query Neighborhood Hits	451	Target Neighborhood Hits	568	Shared Neighborhood Hits	63
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

WASF1_MOUSE
θ value	0.0961366 (rank : 101)	NC score	0.175538 (rank : 89)
Query Neighborhood Hits	451	Target Neighborhood Hits	261	Shared Neighborhood Hits	68
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

CARD6_HUMAN
θ value	0.125558 (rank : 102)	NC score	0.091948 (rank : 314)
Query Neighborhood Hits	451	Target Neighborhood Hits	145	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BX69	Gene names	CARD6
Domain Architecture
Description	Caspase recruitment domain-containing protein 6.

CJ078_MOUSE
θ value	0.125558 (rank : 103)	NC score	0.224594 (rank : 42)
Query Neighborhood Hits	451	Target Neighborhood Hits	559	Shared Neighborhood Hits	100
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

LCP2_HUMAN
θ value	0.125558 (rank : 104)	NC score	0.249713 (rank : 23)
Query Neighborhood Hits	451	Target Neighborhood Hits	531	Shared Neighborhood Hits	171
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

MADCA_HUMAN
θ value	0.125558 (rank : 105)	NC score	0.169025 (rank : 104)
Query Neighborhood Hits	451	Target Neighborhood Hits	221	Shared Neighborhood Hits	50
SwissProt Accessions	Q13477, O60222, O75867	Gene names	MADCAM1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (hMAdCAM-1).

MKL1_MOUSE
θ value	0.125558 (rank : 106)	NC score	0.161281 (rank : 120)
Query Neighborhood Hits	451	Target Neighborhood Hits	667	Shared Neighborhood Hits	171
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

PCLO_MOUSE
θ value	0.125558 (rank : 107)	NC score	0.229893 (rank : 41)
Query Neighborhood Hits	451	Target Neighborhood Hits	2275	Shared Neighborhood Hits	286
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PGCA_HUMAN
θ value	0.125558 (rank : 108)	NC score	0.057006 (rank : 582)
Query Neighborhood Hits	451	Target Neighborhood Hits	821	Shared Neighborhood Hits	64
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

PININ_MOUSE
θ value	0.125558 (rank : 109)	NC score	0.074471 (rank : 412)
Query Neighborhood Hits	451	Target Neighborhood Hits	777	Shared Neighborhood Hits	73
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

RERE_HUMAN
θ value	0.125558 (rank : 110)	NC score	0.170732 (rank : 99)
Query Neighborhood Hits	451	Target Neighborhood Hits	779	Shared Neighborhood Hits	127
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

SFPQ_MOUSE
θ value	0.125558 (rank : 111)	NC score	0.132791 (rank : 171)
Query Neighborhood Hits	451	Target Neighborhood Hits	958	Shared Neighborhood Hits	111
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

SMOO_HUMAN
θ value	0.125558 (rank : 112)	NC score	0.104692 (rank : 256)
Query Neighborhood Hits	451	Target Neighborhood Hits	391	Shared Neighborhood Hits	73
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

G3BP_HUMAN
θ value	0.163984 (rank : 113)	NC score	0.076393 (rank : 394)
Query Neighborhood Hits	451	Target Neighborhood Hits	219	Shared Neighborhood Hits	25
SwissProt Accessions	Q13283	Gene names	G3BP, G3BP1
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 1 (EC 3.6.1.-) (ATP- dependent DNA helicase VIII) (GAP SH3-domain-binding protein 1) (G3BP- 1) (HDH-VIII).

GAK1_HUMAN
θ value	0.163984 (rank : 114)	NC score	0.122192 (rank : 199)
Query Neighborhood Hits	451	Target Neighborhood Hits	268	Shared Neighborhood Hits	100
SwissProt Accessions	P62683	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_12q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

LIPS_HUMAN
θ value	0.163984 (rank : 115)	NC score	0.135537 (rank : 165)
Query Neighborhood Hits	451	Target Neighborhood Hits	314	Shared Neighborhood Hits	85
SwissProt Accessions	Q05469, Q3LRT2, Q6NSL7	Gene names	LIPE
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

PDZD2_HUMAN
θ value	0.163984 (rank : 116)	NC score	0.115960 (rank : 217)
Query Neighborhood Hits	451	Target Neighborhood Hits	772	Shared Neighborhood Hits	111
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

PKHA4_HUMAN
θ value	0.163984 (rank : 117)	NC score	0.088986 (rank : 329)
Query Neighborhood Hits	451	Target Neighborhood Hits	283	Shared Neighborhood Hits	52
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

RIMS2_MOUSE
θ value	0.163984 (rank : 118)	NC score	0.086299 (rank : 343)
Query Neighborhood Hits	451	Target Neighborhood Hits	376	Shared Neighborhood Hits	34
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

ROBO3_MOUSE
θ value	0.163984 (rank : 119)	NC score	0.022525 (rank : 767)
Query Neighborhood Hits	451	Target Neighborhood Hits	524	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Z2I4	Gene names	Robo3, Rbig1
Domain Architecture
Description	Roundabout homolog 3 precursor (Retinoblastoma-inhibiting gene 1) (Rig-1).

SCAP_HUMAN
θ value	0.163984 (rank : 120)	NC score	0.056555 (rank : 588)
Query Neighborhood Hits	451	Target Neighborhood Hits	368	Shared Neighborhood Hits	60
SwissProt Accessions	Q12770, Q8N2E0, Q8WUA1	Gene names	SCAP, KIAA0199
Domain Architecture
Description	Sterol regulatory element-binding protein cleavage-activating protein (SREBP cleavage-activating protein) (SCAP).

TTBK1_HUMAN
θ value	0.163984 (rank : 121)	NC score	0.042894 (rank : 697)
Query Neighborhood Hits	451	Target Neighborhood Hits	1058	Shared Neighborhood Hits	97
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

ZEP2_HUMAN
θ value	0.163984 (rank : 122)	NC score	0.038509 (rank : 710)
Query Neighborhood Hits	451	Target Neighborhood Hits	937	Shared Neighborhood Hits	73
SwissProt Accessions	P31629, Q02646, Q5THT5, Q9NS05	Gene names	HIVEP2
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 (HIV- EP2) (MHC-binding protein 2) (MBP-2).

CF118_HUMAN
θ value	0.21417 (rank : 123)	NC score	0.058572 (rank : 555)
Query Neighborhood Hits	451	Target Neighborhood Hits	154	Shared Neighborhood Hits	8
SwissProt Accessions	Q5T5N4, Q8TC11	Gene names	C6orf118
Domain Architecture	No domain graphic available
Description	Protein C6orf118.

DLGP4_HUMAN
θ value	0.21417 (rank : 124)	NC score	0.040746 (rank : 704)
Query Neighborhood Hits	451	Target Neighborhood Hits	90	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y2H0, Q5T2Y4, Q5T2Y5, Q9H137, Q9H138, Q9H1L7	Gene names	DLGAP4, DAP4, KIAA0964
Domain Architecture
Description	Disks large-associated protein 4 (DAP-4) (SAP90/PSD-95-associated protein 4) (SAPAP4) (PSD-95/SAP90-binding protein 4).

GAK11_HUMAN
θ value	0.21417 (rank : 125)	NC score	0.148242 (rank : 137)
Query Neighborhood Hits	451	Target Neighborhood Hits	409	Shared Neighborhood Hits	149
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK12_HUMAN
θ value	0.21417 (rank : 126)	NC score	0.140429 (rank : 157)
Query Neighborhood Hits	451	Target Neighborhood Hits	374	Shared Neighborhood Hits	144
SwissProt Accessions	P63130, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K102 Gag protein) (HERV-K(III) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK2_HUMAN
θ value	0.21417 (rank : 127)	NC score	0.147155 (rank : 142)
Query Neighborhood Hits	451	Target Neighborhood Hits	406	Shared Neighborhood Hits	148
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK4_HUMAN
θ value	0.21417 (rank : 128)	NC score	0.148707 (rank : 136)
Query Neighborhood Hits	451	Target Neighborhood Hits	415	Shared Neighborhood Hits	149
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK6_HUMAN
θ value	0.21417 (rank : 129)	NC score	0.146161 (rank : 144)
Query Neighborhood Hits	451	Target Neighborhood Hits	392	Shared Neighborhood Hits	142
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

PCGF4_MOUSE
θ value	0.21417 (rank : 130)	NC score	0.038788 (rank : 708)
Query Neighborhood Hits	451	Target Neighborhood Hits	163	Shared Neighborhood Hits	4
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

PRB4S_HUMAN
θ value	0.21417 (rank : 131)	NC score	0.186320 (rank : 80)
Query Neighborhood Hits	451	Target Neighborhood Hits	330	Shared Neighborhood Hits	74
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

RIN3_HUMAN
θ value	0.21417 (rank : 132)	NC score	0.138385 (rank : 161)
Query Neighborhood Hits	451	Target Neighborhood Hits	227	Shared Neighborhood Hits	67
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

STRAD_MOUSE
θ value	0.21417 (rank : 133)	NC score	0.203996 (rank : 55)
Query Neighborhood Hits	451	Target Neighborhood Hits	57	Shared Neighborhood Hits	18
SwissProt Accessions	Q60924	Gene names	Stra13
Domain Architecture	No domain graphic available
Description	Retinoic acid-inducible E3 protein (Hematopoietic-specific protein E3).

UBP21_MOUSE
θ value	0.21417 (rank : 134)	NC score	0.029271 (rank : 740)
Query Neighborhood Hits	451	Target Neighborhood Hits	101	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QZL6, Q9D0R1	Gene names	Usp21, Usp23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21).

CA106_HUMAN
θ value	0.279714 (rank : 135)	NC score	0.077638 (rank : 386)
Query Neighborhood Hits	451	Target Neighborhood Hits	124	Shared Neighborhood Hits	26
SwissProt Accessions	Q3KP66, Q9NV65, Q9NVI0	Gene names	C1orf106
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106.

GAK10_HUMAN
θ value	0.279714 (rank : 136)	NC score	0.131095 (rank : 175)
Query Neighborhood Hits	451	Target Neighborhood Hits	289	Shared Neighborhood Hits	108
SwissProt Accessions	P87889, P10263, P10264, Q69385, Q9UKH6	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q33.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K10 Gag protein) (HERV-K107 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

LR37B_HUMAN
θ value	0.279714 (rank : 137)	NC score	0.061467 (rank : 520)
Query Neighborhood Hits	451	Target Neighborhood Hits	392	Shared Neighborhood Hits	41
SwissProt Accessions	Q96QE4, Q5YKG6	Gene names	LRRC37B
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37B precursor (C66 SLIT-like testicular protein).

LTBP2_HUMAN
θ value	0.279714 (rank : 138)	NC score	0.013741 (rank : 811)
Query Neighborhood Hits	451	Target Neighborhood Hits	552	Shared Neighborhood Hits	27
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

PRB3_HUMAN
θ value	0.279714 (rank : 139)	NC score	0.170078 (rank : 101)
Query Neighborhood Hits	451	Target Neighborhood Hits	318	Shared Neighborhood Hits	78
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

RBM12_HUMAN
θ value	0.279714 (rank : 140)	NC score	0.097462 (rank : 288)
Query Neighborhood Hits	451	Target Neighborhood Hits	298	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NTZ6, O94865, Q8N3B1, Q9H196	Gene names	RBM12, KIAA0765
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

TARA_MOUSE
θ value	0.279714 (rank : 141)	NC score	0.141318 (rank : 156)
Query Neighborhood Hits	451	Target Neighborhood Hits	1133	Shared Neighborhood Hits	150
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

WASF4_HUMAN
θ value	0.279714 (rank : 142)	NC score	0.167871 (rank : 107)
Query Neighborhood Hits	451	Target Neighborhood Hits	282	Shared Neighborhood Hits	81
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

WIRE_HUMAN
θ value	0.279714 (rank : 143)	NC score	0.208549 (rank : 53)
Query Neighborhood Hits	451	Target Neighborhood Hits	329	Shared Neighborhood Hits	84
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

ZN580_HUMAN
θ value	0.279714 (rank : 144)	NC score	0.016884 (rank : 793)
Query Neighborhood Hits	451	Target Neighborhood Hits	727	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UK33, Q9NPP7	Gene names	ZNF580
Domain Architecture	No domain graphic available
Description	Zinc finger protein 580 (LDL-induced EC protein).

CMTA2_MOUSE
θ value	0.365318 (rank : 145)	NC score	0.067364 (rank : 472)
Query Neighborhood Hits	451	Target Neighborhood Hits	216	Shared Neighborhood Hits	34
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

ENAH_MOUSE
θ value	0.365318 (rank : 146)	NC score	0.128527 (rank : 183)
Query Neighborhood Hits	451	Target Neighborhood Hits	919	Shared Neighborhood Hits	118
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

EP300_HUMAN
θ value	0.365318 (rank : 147)	NC score	0.149834 (rank : 133)
Query Neighborhood Hits	451	Target Neighborhood Hits	821	Shared Neighborhood Hits	143
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

GGN_HUMAN
θ value	0.365318 (rank : 148)	NC score	0.159104 (rank : 122)
Query Neighborhood Hits	451	Target Neighborhood Hits	269	Shared Neighborhood Hits	70
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

HXB4_HUMAN
θ value	0.365318 (rank : 149)	NC score	0.026984 (rank : 746)
Query Neighborhood Hits	451	Target Neighborhood Hits	376	Shared Neighborhood Hits	24
SwissProt Accessions	P17483, Q9NTA0	Gene names	HOXB4, HOX2F
Domain Architecture
Description	Homeobox protein Hox-B4 (Hox-2F) (Hox-2.6).

ICK_MOUSE
θ value	0.365318 (rank : 150)	NC score	0.009350 (rank : 827)
Query Neighborhood Hits	451	Target Neighborhood Hits	860	Shared Neighborhood Hits	37
SwissProt Accessions	Q9JKV2, Q8K138	Gene names	Ick
Domain Architecture
Description	Serine/threonine-protein kinase ICK (EC 2.7.11.22) (Intestinal cell kinase) (mICK) (MAK-related kinase) (MRK).

IRS2_HUMAN
θ value	0.365318 (rank : 151)	NC score	0.074014 (rank : 417)
Query Neighborhood Hits	451	Target Neighborhood Hits	262	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

LAD1_MOUSE
θ value	0.365318 (rank : 152)	NC score	0.230937 (rank : 40)
Query Neighborhood Hits	451	Target Neighborhood Hits	391	Shared Neighborhood Hits	110
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

LRC56_HUMAN
θ value	0.365318 (rank : 153)	NC score	0.108361 (rank : 245)
Query Neighborhood Hits	451	Target Neighborhood Hits	165	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IYG6, Q8N3Q4	Gene names	LRRC56
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 56.

MDC1_HUMAN
θ value	0.365318 (rank : 154)	NC score	0.297607 (rank : 8)
Query Neighborhood Hits	451	Target Neighborhood Hits	1446	Shared Neighborhood Hits	240
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

NIPBL_HUMAN
θ value	0.365318 (rank : 155)	NC score	0.168273 (rank : 106)
Query Neighborhood Hits	451	Target Neighborhood Hits	1311	Shared Neighborhood Hits	168
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

SPR1A_MOUSE
θ value	0.365318 (rank : 156)	NC score	0.185347 (rank : 81)
Query Neighborhood Hits	451	Target Neighborhood Hits	343	Shared Neighborhood Hits	119
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

WASF2_HUMAN
θ value	0.365318 (rank : 157)	NC score	0.161563 (rank : 119)
Query Neighborhood Hits	451	Target Neighborhood Hits	280	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

ZF106_MOUSE
θ value	0.365318 (rank : 158)	NC score	0.041219 (rank : 703)
Query Neighborhood Hits	451	Target Neighborhood Hits	472	Shared Neighborhood Hits	43
SwissProt Accessions	O88466, O55185, O88465, O88467, Q792M1, Q792P4, Q8CDZ8, Q8R3I4, Q9ESU3	Gene names	Zfp106, H3a, Sh3bp3, Sirm, Znf474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 (Zfp-106) (Zinc finger protein 474) (H3a minor histocompatibility antigen) (Son of insulin receptor mutant).

AIPL1_HUMAN
θ value	0.47712 (rank : 159)	NC score	0.047973 (rank : 689)
Query Neighborhood Hits	451	Target Neighborhood Hits	113	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NZN9, Q9H873, Q9NS10	Gene names	AIPL1
Domain Architecture
Description	Aryl-hydrocarbon-interacting protein-like 1.

BBX_HUMAN
θ value	0.47712 (rank : 160)	NC score	0.030620 (rank : 735)
Query Neighborhood Hits	451	Target Neighborhood Hits	167	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WY36, Q2TAJ1, Q7L3J8, Q7LBY8, Q8NDB0, Q8WY35, Q9H0J6	Gene names	BBX, HBP2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

EVX1_MOUSE
θ value	0.47712 (rank : 161)	NC score	0.017441 (rank : 789)
Query Neighborhood Hits	451	Target Neighborhood Hits	350	Shared Neighborhood Hits	15
SwissProt Accessions	P23683	Gene names	Evx1
Domain Architecture
Description	Homeobox even-skipped homolog protein 1 (EVX-1).

GGN_MOUSE
θ value	0.47712 (rank : 162)	NC score	0.166395 (rank : 110)
Query Neighborhood Hits	451	Target Neighborhood Hits	311	Shared Neighborhood Hits	69
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

IQEC2_HUMAN
θ value	0.47712 (rank : 163)	NC score	0.069481 (rank : 453)
Query Neighborhood Hits	451	Target Neighborhood Hits	403	Shared Neighborhood Hits	81
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IQEC2_MOUSE
θ value	0.47712 (rank : 164)	NC score	0.072634 (rank : 427)
Query Neighborhood Hits	451	Target Neighborhood Hits	417	Shared Neighborhood Hits	83
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

JARD2_HUMAN
θ value	0.47712 (rank : 165)	NC score	0.038329 (rank : 711)
Query Neighborhood Hits	451	Target Neighborhood Hits	119	Shared Neighborhood Hits	21
SwissProt Accessions	Q92833, Q5U5L5	Gene names	JARID2, JMJ
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

PCD15_MOUSE
θ value	0.47712 (rank : 166)	NC score	0.032460 (rank : 731)
Query Neighborhood Hits	451	Target Neighborhood Hits	262	Shared Neighborhood Hits	40
SwissProt Accessions	Q99PJ1	Gene names	Pcdh15
Domain Architecture
Description	Protocadherin-15 precursor.

SPR1B_MOUSE
θ value	0.47712 (rank : 167)	NC score	0.246960 (rank : 25)
Query Neighborhood Hits	451	Target Neighborhood Hits	395	Shared Neighborhood Hits	143
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

TULP4_HUMAN
θ value	0.47712 (rank : 168)	NC score	0.139273 (rank : 159)
Query Neighborhood Hits	451	Target Neighborhood Hits	426	Shared Neighborhood Hits	124
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

WBS14_HUMAN
θ value	0.47712 (rank : 169)	NC score	0.114550 (rank : 219)
Query Neighborhood Hits	451	Target Neighborhood Hits	273	Shared Neighborhood Hits	55
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

YLPM1_MOUSE
θ value	0.47712 (rank : 170)	NC score	0.142591 (rank : 153)
Query Neighborhood Hits	451	Target Neighborhood Hits	505	Shared Neighborhood Hits	88
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

ANTR1_HUMAN
θ value	0.62314 (rank : 171)	NC score	0.080476 (rank : 367)
Query Neighborhood Hits	451	Target Neighborhood Hits	128	Shared Neighborhood Hits	43
SwissProt Accessions	Q9H6X2, Q96P02, Q9NVP3	Gene names	ANTXR1, ATR, TEM8
Domain Architecture
Description	Anthrax toxin receptor 1 precursor (Tumor endothelial marker 8).

HBS1L_MOUSE
θ value	0.62314 (rank : 172)	NC score	0.021396 (rank : 773)
Query Neighborhood Hits	451	Target Neighborhood Hits	65	Shared Neighborhood Hits	6
SwissProt Accessions	Q69ZS7, Q91Z32, Q9CVT2, Q9CZ95, Q9WTY5	Gene names	Hbs1l, Hbs1, Kiaa1038
Domain Architecture	No domain graphic available
Description	HBS1-like protein.

K1543_HUMAN
θ value	0.62314 (rank : 173)	NC score	0.156076 (rank : 125)
Query Neighborhood Hits	451	Target Neighborhood Hits	435	Shared Neighborhood Hits	130
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

MS3L1_MOUSE
θ value	0.62314 (rank : 174)	NC score	0.053888 (rank : 631)
Query Neighborhood Hits	451	Target Neighborhood Hits	67	Shared Neighborhood Hits	13
SwissProt Accessions	Q9WVG9	Gene names	Msl3l1, Msl31
Domain Architecture
Description	Male-specific lethal 3-like 1 (MSL3-like 1) (Male-specific lethal-3 homolog 1).

PABP3_HUMAN
θ value	0.62314 (rank : 175)	NC score	0.026644 (rank : 747)
Query Neighborhood Hits	451	Target Neighborhood Hits	259	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H361, Q8NHV0, Q9H086	Gene names	PABPC3, PABP3, PABPL3
Domain Architecture
Description	Polyadenylate-binding protein 3 (Poly(A)-binding protein 3) (PABP 3) (Testis-specific poly(A)-binding protein).

SFR12_MOUSE
θ value	0.62314 (rank : 176)	NC score	0.080682 (rank : 366)
Query Neighborhood Hits	451	Target Neighborhood Hits	486	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

TITIN_HUMAN
θ value	0.62314 (rank : 177)	NC score	0.060229 (rank : 533)
Query Neighborhood Hits	451	Target Neighborhood Hits	2923	Shared Neighborhood Hits	194
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

TOP2A_HUMAN
θ value	0.62314 (rank : 178)	NC score	0.036929 (rank : 718)
Query Neighborhood Hits	451	Target Neighborhood Hits	135	Shared Neighborhood Hits	17
SwissProt Accessions	P11388, Q71UN1, Q9HB24, Q9HB25, Q9HB26, Q9UP44, Q9UQP9	Gene names	TOP2A, TOP2
Domain Architecture
Description	DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme).

TROAP_HUMAN
θ value	0.62314 (rank : 179)	NC score	0.193773 (rank : 73)
Query Neighborhood Hits	451	Target Neighborhood Hits	258	Shared Neighborhood Hits	86
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

ZNF16_HUMAN
θ value	0.62314 (rank : 180)	NC score	-0.002744 (rank : 849)
Query Neighborhood Hits	451	Target Neighborhood Hits	771	Shared Neighborhood Hits	20
SwissProt Accessions	P17020, Q96FG0	Gene names	ZNF16, KOX9
Domain Architecture	No domain graphic available
Description	Zinc finger protein 16 (Zinc finger protein KOX9).

ZYX_MOUSE
θ value	0.62314 (rank : 181)	NC score	0.066024 (rank : 489)
Query Neighborhood Hits	451	Target Neighborhood Hits	347	Shared Neighborhood Hits	52
SwissProt Accessions	Q62523, P70461	Gene names	Zyx
Domain Architecture
Description	Zyxin.

BAI1_MOUSE
θ value	0.813845 (rank : 182)	NC score	0.034520 (rank : 722)
Query Neighborhood Hits	451	Target Neighborhood Hits	340	Shared Neighborhood Hits	50
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAT2_MOUSE
θ value	0.813845 (rank : 183)	NC score	0.196984 (rank : 67)
Query Neighborhood Hits	451	Target Neighborhood Hits	947	Shared Neighborhood Hits	192
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CD2_HUMAN
θ value	0.813845 (rank : 184)	NC score	0.233870 (rank : 39)
Query Neighborhood Hits	451	Target Neighborhood Hits	504	Shared Neighborhood Hits	161
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

CEND3_HUMAN
θ value	0.813845 (rank : 185)	NC score	0.030411 (rank : 737)
Query Neighborhood Hits	451	Target Neighborhood Hits	275	Shared Neighborhood Hits	39
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

CO039_HUMAN
θ value	0.813845 (rank : 186)	NC score	0.101205 (rank : 271)
Query Neighborhood Hits	451	Target Neighborhood Hits	264	Shared Neighborhood Hits	73
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

EGR2_MOUSE
θ value	0.813845 (rank : 187)	NC score	0.002882 (rank : 845)
Query Neighborhood Hits	451	Target Neighborhood Hits	745	Shared Neighborhood Hits	29
SwissProt Accessions	P08152	Gene names	Egr2, Egr-2, Krox-20, Zfp-25
Domain Architecture	No domain graphic available
Description	Early growth response protein 2 (EGR-2) (Krox-20 protein).

ENL_HUMAN
θ value	0.813845 (rank : 188)	NC score	0.112849 (rank : 226)
Query Neighborhood Hits	451	Target Neighborhood Hits	305	Shared Neighborhood Hits	49
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

HXA3_HUMAN
θ value	0.813845 (rank : 189)	NC score	0.038302 (rank : 712)
Query Neighborhood Hits	451	Target Neighborhood Hits	535	Shared Neighborhood Hits	66
SwissProt Accessions	O43365	Gene names	HOXA3, HOX1E
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1E).

MAK_MOUSE
θ value	0.813845 (rank : 190)	NC score	0.009864 (rank : 825)
Query Neighborhood Hits	451	Target Neighborhood Hits	873	Shared Neighborhood Hits	37
SwissProt Accessions	Q04859	Gene names	Mak, Rck
Domain Architecture
Description	Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male germ cell- associated kinase) (Protein kinase RCK).

MAP4_HUMAN
θ value	0.813845 (rank : 191)	NC score	0.165541 (rank : 114)
Query Neighborhood Hits	451	Target Neighborhood Hits	428	Shared Neighborhood Hits	94
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

PCNT_HUMAN
θ value	0.813845 (rank : 192)	NC score	0.035139 (rank : 721)
Query Neighborhood Hits	451	Target Neighborhood Hits	1551	Shared Neighborhood Hits	88
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

PHAR2_HUMAN
θ value	0.813845 (rank : 193)	NC score	0.095814 (rank : 298)
Query Neighborhood Hits	451	Target Neighborhood Hits	208	Shared Neighborhood Hits	36
SwissProt Accessions	O75167, Q68DM2	Gene names	PHACTR2, C6orf56, KIAA0680
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 2.

PHLB1_HUMAN
θ value	0.813845 (rank : 194)	NC score	0.098932 (rank : 280)
Query Neighborhood Hits	451	Target Neighborhood Hits	1038	Shared Neighborhood Hits	131
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PRCC_HUMAN
θ value	0.813845 (rank : 195)	NC score	0.114386 (rank : 221)
Query Neighborhood Hits	451	Target Neighborhood Hits	109	Shared Neighborhood Hits	35
SwissProt Accessions	Q92733, O00665, O00724	Gene names	PRCC, TPRC
Domain Architecture	No domain graphic available
Description	Proline-rich protein PRCC (Papillary renal cell carcinoma translocation-associated gene protein).

ADAM8_HUMAN
θ value	1.06291 (rank : 196)	NC score	0.014212 (rank : 810)
Query Neighborhood Hits	451	Target Neighborhood Hits	327	Shared Neighborhood Hits	25
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

ARHGF_HUMAN
θ value	1.06291 (rank : 197)	NC score	0.055555 (rank : 600)
Query Neighborhood Hits	451	Target Neighborhood Hits	214	Shared Neighborhood Hits	42
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

ATX2_HUMAN
θ value	1.06291 (rank : 198)	NC score	0.097010 (rank : 291)
Query Neighborhood Hits	451	Target Neighborhood Hits	375	Shared Neighborhood Hits	75
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

ATX2_MOUSE
θ value	1.06291 (rank : 199)	NC score	0.120522 (rank : 204)
Query Neighborhood Hits	451	Target Neighborhood Hits	445	Shared Neighborhood Hits	99
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

AUTS2_HUMAN
θ value	1.06291 (rank : 200)	NC score	0.118622 (rank : 212)
Query Neighborhood Hits	451	Target Neighborhood Hits	342	Shared Neighborhood Hits	86
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

CMTA2_HUMAN
θ value	1.06291 (rank : 201)	NC score	0.066512 (rank : 483)
Query Neighborhood Hits	451	Target Neighborhood Hits	199	Shared Neighborhood Hits	26
SwissProt Accessions	O94983, Q7Z6M8, Q8N3V0, Q8NDG4, Q96G17	Gene names	CAMTA2, KIAA0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

DNMT1_MOUSE
θ value	1.06291 (rank : 202)	NC score	0.049313 (rank : 686)
Query Neighborhood Hits	451	Target Neighborhood Hits	137	Shared Neighborhood Hits	19
SwissProt Accessions	P13864, P97413, Q80ZU3, Q9CSC6, Q9QXX6	Gene names	Dnmt1, Dnmt, Met1, Uim
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase MmuI) (DNA MTase MmuI) (MCMT) (M.MmuI) (Met-1).

DREB_MOUSE
θ value	1.06291 (rank : 203)	NC score	0.050939 (rank : 675)
Query Neighborhood Hits	451	Target Neighborhood Hits	446	Shared Neighborhood Hits	38
SwissProt Accessions	Q9QXS6, Q922X1, Q9QXS5	Gene names	Dbn1, Drba
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

FIBB_HUMAN
θ value	1.06291 (rank : 204)	NC score	0.020992 (rank : 777)
Query Neighborhood Hits	451	Target Neighborhood Hits	101	Shared Neighborhood Hits	4
SwissProt Accessions	P02675	Gene names	FGB
Domain Architecture
Description	Fibrinogen beta chain precursor [Contains: Fibrinopeptide B].

FRM4A_MOUSE
θ value	1.06291 (rank : 205)	NC score	0.020050 (rank : 782)
Query Neighborhood Hits	451	Target Neighborhood Hits	108	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BIE6, Q6PDJ4, Q8CHA6	Gene names	Frmd4a, Frmd4, Kiaa1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

GA2L2_MOUSE
θ value	1.06291 (rank : 206)	NC score	0.172286 (rank : 91)
Query Neighborhood Hits	451	Target Neighborhood Hits	395	Shared Neighborhood Hits	127
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

GAK5_HUMAN
θ value	1.06291 (rank : 207)	NC score	0.148219 (rank : 139)
Query Neighborhood Hits	451	Target Neighborhood Hits	429	Shared Neighborhood Hits	154
SwissProt Accessions	P62684	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K113 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

IRS1_MOUSE
θ value	1.06291 (rank : 208)	NC score	0.044558 (rank : 695)
Query Neighborhood Hits	451	Target Neighborhood Hits	112	Shared Neighborhood Hits	23
SwissProt Accessions	P35569	Gene names	Irs1, Irs-1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

MYPN_MOUSE
θ value	1.06291 (rank : 209)	NC score	0.050002 (rank : 684)
Query Neighborhood Hits	451	Target Neighborhood Hits	421	Shared Neighborhood Hits	25
SwissProt Accessions	Q5DTJ9, Q7TPW5, Q8BZ76	Gene names	Mypn, Kiaa4170
Domain Architecture	No domain graphic available
Description	Myopalladin.

PCGF4_HUMAN
θ value	1.06291 (rank : 210)	NC score	0.032999 (rank : 729)
Query Neighborhood Hits	451	Target Neighborhood Hits	161	Shared Neighborhood Hits	3
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

PHF20_HUMAN
θ value	1.06291 (rank : 211)	NC score	0.081705 (rank : 359)
Query Neighborhood Hits	451	Target Neighborhood Hits	394	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

PKCB1_HUMAN
θ value	1.06291 (rank : 212)	NC score	0.090644 (rank : 324)
Query Neighborhood Hits	451	Target Neighborhood Hits	488	Shared Neighborhood Hits	68
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

PO6F2_MOUSE
θ value	1.06291 (rank : 213)	NC score	0.069587 (rank : 450)
Query Neighborhood Hits	451	Target Neighborhood Hits	639	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

PRP2_MOUSE
θ value	1.06291 (rank : 214)	NC score	0.199737 (rank : 63)
Query Neighborhood Hits	451	Target Neighborhood Hits	347	Shared Neighborhood Hits	77
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

SCEL_MOUSE
θ value	1.06291 (rank : 215)	NC score	0.033271 (rank : 726)
Query Neighborhood Hits	451	Target Neighborhood Hits	89	Shared Neighborhood Hits	12
SwissProt Accessions	Q9EQG3, Q9CTT9	Gene names	Scel
Domain Architecture
Description	Sciellin.

SH3K1_HUMAN
θ value	1.06291 (rank : 216)	NC score	0.041473 (rank : 700)
Query Neighborhood Hits	451	Target Neighborhood Hits	341	Shared Neighborhood Hits	32
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

SPEG_MOUSE
θ value	1.06291 (rank : 217)	NC score	0.066091 (rank : 488)
Query Neighborhood Hits	451	Target Neighborhood Hits	1959	Shared Neighborhood Hits	219
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SYNJ1_MOUSE
θ value	1.06291 (rank : 218)	NC score	0.150578 (rank : 132)
Query Neighborhood Hits	451	Target Neighborhood Hits	516	Shared Neighborhood Hits	144
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

TRDN_HUMAN
θ value	1.06291 (rank : 219)	NC score	0.098015 (rank : 284)
Query Neighborhood Hits	451	Target Neighborhood Hits	542	Shared Neighborhood Hits	51
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

TRI66_MOUSE
θ value	1.06291 (rank : 220)	NC score	0.094617 (rank : 302)
Query Neighborhood Hits	451	Target Neighborhood Hits	491	Shared Neighborhood Hits	95
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

WASF2_MOUSE
θ value	1.06291 (rank : 221)	NC score	0.168506 (rank : 105)
Query Neighborhood Hits	451	Target Neighborhood Hits	315	Shared Neighborhood Hits	84
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

WASF3_HUMAN
θ value	1.06291 (rank : 222)	NC score	0.139606 (rank : 158)
Query Neighborhood Hits	451	Target Neighborhood Hits	204	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UPY6, O94974	Gene names	WASF3, KIAA0900, SCAR3, WAVE3
Domain Architecture
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3) (Verprolin homology domain-containing protein 3).

WASP_HUMAN
θ value	1.06291 (rank : 223)	NC score	0.169271 (rank : 103)
Query Neighborhood Hits	451	Target Neighborhood Hits	195	Shared Neighborhood Hits	63
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

2A5D_HUMAN
θ value	1.38821 (rank : 224)	NC score	0.021414 (rank : 772)
Query Neighborhood Hits	451	Target Neighborhood Hits	59	Shared Neighborhood Hits	9
SwissProt Accessions	Q14738, O00494, O00696, Q15171	Gene names	PPP2R5D
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PP2A, B subunit, B' delta isoform) (PP2A, B subunit, B56 delta isoform) (PP2A, B subunit, PR61 delta isoform) (PP2A, B subunit, R5 delta isoform).

ADDB_MOUSE
θ value	1.38821 (rank : 225)	NC score	0.080111 (rank : 369)
Query Neighborhood Hits	451	Target Neighborhood Hits	574	Shared Neighborhood Hits	86
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

BAI1_HUMAN
θ value	1.38821 (rank : 226)	NC score	0.038166 (rank : 713)
Query Neighborhood Hits	451	Target Neighborhood Hits	375	Shared Neighborhood Hits	60
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

CAC1E_MOUSE
θ value	1.38821 (rank : 227)	NC score	0.015352 (rank : 801)
Query Neighborhood Hits	451	Target Neighborhood Hits	167	Shared Neighborhood Hits	13
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CPSF7_HUMAN
θ value	1.38821 (rank : 228)	NC score	0.074756 (rank : 408)
Query Neighborhood Hits	451	Target Neighborhood Hits	125	Shared Neighborhood Hits	30
SwissProt Accessions	Q8N684, Q7Z3H9, Q9H025, Q9H9V1	Gene names	CPSF7
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 7 (Cleavage and polyadenylation specificity factor 59 kDa subunit) (CPSF 59 kDa subunit) (Pre-mRNA cleavage factor Im 59 kDa subunit).

CPSF7_MOUSE
θ value	1.38821 (rank : 229)	NC score	0.074625 (rank : 410)
Query Neighborhood Hits	451	Target Neighborhood Hits	123	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BTV2, Q3TNF1, Q8BKE7, Q8CFS8	Gene names	Cpsf7
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 7.

DAAM1_MOUSE
θ value	1.38821 (rank : 230)	NC score	0.103466 (rank : 263)
Query Neighborhood Hits	451	Target Neighborhood Hits	443	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BPM0, Q80Y68, Q9CQQ2	Gene names	Daam1
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

DIAP2_HUMAN
θ value	1.38821 (rank : 231)	NC score	0.145461 (rank : 149)
Query Neighborhood Hits	451	Target Neighborhood Hits	342	Shared Neighborhood Hits	50
SwissProt Accessions	O60879, O60878, Q8WX06, Q8WX48, Q9UJL2	Gene names	DIAPH2, DIA
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2).

JPH2_MOUSE
θ value	1.38821 (rank : 232)	NC score	0.063277 (rank : 503)
Query Neighborhood Hits	451	Target Neighborhood Hits	279	Shared Neighborhood Hits	59
SwissProt Accessions	Q9ET78, Q9ET79	Gene names	Jph2, Jp2
Domain Architecture	No domain graphic available
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

KSR2_HUMAN
θ value	1.38821 (rank : 233)	NC score	0.014705 (rank : 806)
Query Neighborhood Hits	451	Target Neighborhood Hits	920	Shared Neighborhood Hits	64
SwissProt Accessions	Q6VAB6, Q8N775	Gene names	KSR2
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-2 (hKSR2).

MEGF9_HUMAN
θ value	1.38821 (rank : 234)	NC score	0.045240 (rank : 693)
Query Neighborhood Hits	451	Target Neighborhood Hits	557	Shared Neighborhood Hits	53
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

NCOR2_MOUSE
θ value	1.38821 (rank : 235)	NC score	0.117574 (rank : 213)
Query Neighborhood Hits	451	Target Neighborhood Hits	790	Shared Neighborhood Hits	115
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

PELP1_HUMAN
θ value	1.38821 (rank : 236)	NC score	0.116605 (rank : 214)
Query Neighborhood Hits	451	Target Neighborhood Hits	596	Shared Neighborhood Hits	71
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

PSL1_HUMAN
θ value	1.38821 (rank : 237)	NC score	0.171995 (rank : 93)
Query Neighborhood Hits	451	Target Neighborhood Hits	650	Shared Neighborhood Hits	178
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

SFR12_HUMAN
θ value	1.38821 (rank : 238)	NC score	0.064602 (rank : 498)
Query Neighborhood Hits	451	Target Neighborhood Hits	553	Shared Neighborhood Hits	38
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

SOCS7_MOUSE
θ value	1.38821 (rank : 239)	NC score	0.023394 (rank : 763)
Query Neighborhood Hits	451	Target Neighborhood Hits	154	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VHQ2	Gene names	Socs7, Cish7, Nap4
Domain Architecture
Description	Suppressor of cytokine signaling 7 (SOCS-7).

WDR46_HUMAN
θ value	1.38821 (rank : 240)	NC score	0.036944 (rank : 717)
Query Neighborhood Hits	451	Target Neighborhood Hits	147	Shared Neighborhood Hits	16
SwissProt Accessions	O15213, Q5STK5	Gene names	WDR46, BING4, C6orf11
Domain Architecture
Description	WD repeat protein 46 (WD repeat protein BING4).

WNK2_HUMAN
θ value	1.38821 (rank : 241)	NC score	0.050804 (rank : 677)
Query Neighborhood Hits	451	Target Neighborhood Hits	1407	Shared Neighborhood Hits	157
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

ZYX_HUMAN
θ value	1.38821 (rank : 242)	NC score	0.063353 (rank : 502)
Query Neighborhood Hits	451	Target Neighborhood Hits	387	Shared Neighborhood Hits	65
SwissProt Accessions	Q15942	Gene names	ZYX
Domain Architecture
Description	Zyxin (Zyxin-2).

AB1IP_HUMAN
θ value	1.81305 (rank : 243)	NC score	0.129591 (rank : 177)
Query Neighborhood Hits	451	Target Neighborhood Hits	213	Shared Neighborhood Hits	51
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

ARI1A_HUMAN
θ value	1.81305 (rank : 244)	NC score	0.124766 (rank : 190)
Query Neighborhood Hits	451	Target Neighborhood Hits	787	Shared Neighborhood Hits	144
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

BAG3_MOUSE
θ value	1.81305 (rank : 245)	NC score	0.189182 (rank : 76)
Query Neighborhood Hits	451	Target Neighborhood Hits	513	Shared Neighborhood Hits	162
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

CA106_MOUSE
θ value	1.81305 (rank : 246)	NC score	0.069948 (rank : 448)
Query Neighborhood Hits	451	Target Neighborhood Hits	89	Shared Neighborhood Hits	24
SwissProt Accessions	Q7TN12, Q7TN27, Q8BGK3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106 homolog.

CAC1E_HUMAN
θ value	1.81305 (rank : 247)	NC score	0.015332 (rank : 802)
Query Neighborhood Hits	451	Target Neighborhood Hits	148	Shared Neighborhood Hits	14
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CD2L5_HUMAN
θ value	1.81305 (rank : 248)	NC score	0.013156 (rank : 817)
Query Neighborhood Hits	451	Target Neighborhood Hits	987	Shared Neighborhood Hits	55
SwissProt Accessions	Q14004, Q6DKQ9, Q75MH4, Q75MH5, Q96JN4, Q9H4A0, Q9H4A1, Q9UDR4	Gene names	CDC2L5, CDC2L, CHED, KIAA1791
Domain Architecture
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5) (Cholinesterase-related cell division controller).

FA53C_HUMAN
θ value	1.81305 (rank : 249)	NC score	0.050402 (rank : 682)
Query Neighborhood Hits	451	Target Neighborhood Hits	29	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NYF3	Gene names	FAM53C, C5orf6
Domain Architecture	No domain graphic available
Description	Protein FAM53C.

FA53C_MOUSE
θ value	1.81305 (rank : 250)	NC score	0.060175 (rank : 536)
Query Neighborhood Hits	451	Target Neighborhood Hits	40	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BXQ8, Q3U4J2	Gene names	Fam53c
Domain Architecture	No domain graphic available
Description	Protein FAM53C.

FHOD1_MOUSE
θ value	1.81305 (rank : 251)	NC score	0.160635 (rank : 121)
Query Neighborhood Hits	451	Target Neighborhood Hits	217	Shared Neighborhood Hits	51
SwissProt Accessions	Q6P9Q4, Q8BMK2	Gene names	Fhod1, Fhos1
Domain Architecture	No domain graphic available
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

FOXJ3_MOUSE
θ value	1.81305 (rank : 252)	NC score	0.016718 (rank : 794)
Query Neighborhood Hits	451	Target Neighborhood Hits	190	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BUR3, Q3UTD8	Gene names	Foxj3, Kiaa1041
Domain Architecture
Description	Forkhead box protein J3.

HXA3_MOUSE
θ value	1.81305 (rank : 253)	NC score	0.043429 (rank : 696)
Query Neighborhood Hits	451	Target Neighborhood Hits	558	Shared Neighborhood Hits	71
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

LCP2_MOUSE
θ value	1.81305 (rank : 254)	NC score	0.070659 (rank : 442)
Query Neighborhood Hits	451	Target Neighborhood Hits	177	Shared Neighborhood Hits	34
SwissProt Accessions	Q60787	Gene names	Lcp2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

PI5PA_MOUSE
θ value	1.81305 (rank : 255)	NC score	0.109894 (rank : 236)
Query Neighborhood Hits	451	Target Neighborhood Hits	331	Shared Neighborhood Hits	80
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PKHA6_HUMAN
θ value	1.81305 (rank : 256)	NC score	0.059545 (rank : 544)
Query Neighborhood Hits	451	Target Neighborhood Hits	556	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PO6F2_HUMAN
θ value	1.81305 (rank : 257)	NC score	0.061265 (rank : 523)
Query Neighborhood Hits	451	Target Neighborhood Hits	618	Shared Neighborhood Hits	79
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

PRR8_HUMAN
θ value	1.81305 (rank : 258)	NC score	0.121850 (rank : 200)
Query Neighborhood Hits	451	Target Neighborhood Hits	217	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NSV0	Gene names	PRR8
Domain Architecture	No domain graphic available
Description	Proline-rich protein 8.

RANB3_HUMAN
θ value	1.81305 (rank : 259)	NC score	0.052432 (rank : 652)
Query Neighborhood Hits	451	Target Neighborhood Hits	117	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H6Z4, O60405, O75759, O75760, Q9BT47, Q9UG74	Gene names	RANBP3
Domain Architecture	No domain graphic available
Description	Ran-binding protein 3 (RanBP3).

TRI66_HUMAN
θ value	1.81305 (rank : 260)	NC score	0.082249 (rank : 357)
Query Neighborhood Hits	451	Target Neighborhood Hits	479	Shared Neighborhood Hits	92
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TTF1_MOUSE
θ value	1.81305 (rank : 261)	NC score	0.084922 (rank : 348)
Query Neighborhood Hits	451	Target Neighborhood Hits	277	Shared Neighborhood Hits	53
SwissProt Accessions	Q62187, Q9JKK5	Gene names	Ttf1
Domain Architecture	No domain graphic available
Description	Transcription termination factor 1 (TTF-1) (TTF-I) (mTFF-I) (RNA polymerase I termination factor).

WASF3_MOUSE
θ value	1.81305 (rank : 262)	NC score	0.127681 (rank : 184)
Query Neighborhood Hits	451	Target Neighborhood Hits	188	Shared Neighborhood Hits	53
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

Z3H7B_HUMAN
θ value	1.81305 (rank : 263)	NC score	0.020729 (rank : 779)
Query Neighborhood Hits	451	Target Neighborhood Hits	109	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UGR2, Q5TFX9, Q8TBT9, Q9H8B6, Q9UGQ9, Q9UGR0, Q9UGR1, Q9UK03, Q9UPW9	Gene names	ZC3H7B, KIAA1031
Domain Architecture
Description	Zinc finger CCCH-type domain-containing protein 7B (Rotavirus 'X'- associated non-structural protein) (RoXaN).

ZN553_HUMAN
θ value	1.81305 (rank : 264)	NC score	0.001397 (rank : 846)
Query Neighborhood Hits	451	Target Neighborhood Hits	760	Shared Neighborhood Hits	28
SwissProt Accessions	Q96MX3, Q4G0R3, Q69YP3, Q96IL9	Gene names	ZNF553
Domain Architecture	No domain graphic available
Description	Zinc finger protein 553.

ZN579_MOUSE
θ value	1.81305 (rank : 265)	NC score	0.001256 (rank : 847)
Query Neighborhood Hits	451	Target Neighborhood Hits	719	Shared Neighborhood Hits	24
SwissProt Accessions	Q80VM4	Gene names	Znf579, Zfp579
Domain Architecture	No domain graphic available
Description	Zinc finger protein 579.

AFF2_MOUSE
θ value	2.36792 (rank : 266)	NC score	0.124717 (rank : 191)
Query Neighborhood Hits	451	Target Neighborhood Hits	225	Shared Neighborhood Hits	78
SwissProt Accessions	O55112	Gene names	Aff2, Fmr2, Ox19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation protein 2 homolog) (Protein FMR-2) (FMR2P) (Protein Ox19).

ATS19_HUMAN
θ value	2.36792 (rank : 267)	NC score	0.012903 (rank : 818)
Query Neighborhood Hits	451	Target Neighborhood Hits	203	Shared Neighborhood Hits	26
SwissProt Accessions	Q8TE59	Gene names	ADAMTS19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

BRDT_MOUSE
θ value	2.36792 (rank : 268)	NC score	0.065573 (rank : 493)
Query Neighborhood Hits	451	Target Neighborhood Hits	243	Shared Neighborhood Hits	25
SwissProt Accessions	Q91Y44, Q59HJ4	Gene names	Brdt, Fsrg3
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein) (Bromodomain- containing female sterile homeotic-like protein).

CLCN1_HUMAN
θ value	2.36792 (rank : 269)	NC score	0.018492 (rank : 784)
Query Neighborhood Hits	451	Target Neighborhood Hits	89	Shared Neighborhood Hits	22
SwissProt Accessions	P35523	Gene names	CLCN1, CLC1
Domain Architecture
Description	Chloride channel protein, skeletal muscle (Chloride channel protein 1) (ClC-1).

DPOD3_HUMAN
θ value	2.36792 (rank : 270)	NC score	0.054175 (rank : 625)
Query Neighborhood Hits	451	Target Neighborhood Hits	109	Shared Neighborhood Hits	21
SwissProt Accessions	Q15054	Gene names	POLD3, KIAA0039
Domain Architecture	No domain graphic available
Description	DNA polymerase subunit delta 3 (DNA polymerase subunit delta p66).

FOXC1_MOUSE
θ value	2.36792 (rank : 271)	NC score	0.022581 (rank : 766)
Query Neighborhood Hits	451	Target Neighborhood Hits	218	Shared Neighborhood Hits	36
SwissProt Accessions	Q61572, O88409, Q61582	Gene names	Foxc1, Fkh1, Fkhl7, Freac3, Mf1
Domain Architecture
Description	Forkhead box protein C1 (Forkhead-related protein FKHL7) (Forkhead- related transcription factor 3) (FREAC-3) (Transcription factor FKH-1) (Mesoderm/mesenchyme forkhead 1) (MF-1).

GSCR1_HUMAN
θ value	2.36792 (rank : 272)	NC score	0.161658 (rank : 118)
Query Neighborhood Hits	451	Target Neighborhood Hits	674	Shared Neighborhood Hits	131
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

HSF1_HUMAN
θ value	2.36792 (rank : 273)	NC score	0.041400 (rank : 701)
Query Neighborhood Hits	451	Target Neighborhood Hits	163	Shared Neighborhood Hits	37
SwissProt Accessions	Q00613	Gene names	HSF1, HSTF1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

INP5E_MOUSE
θ value	2.36792 (rank : 274)	NC score	0.054598 (rank : 618)
Query Neighborhood Hits	451	Target Neighborhood Hits	59	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JII1, Q3TCC9	Gene names	Inpp5e
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

MAST3_HUMAN
θ value	2.36792 (rank : 275)	NC score	0.013520 (rank : 813)
Query Neighborhood Hits	451	Target Neighborhood Hits	1128	Shared Neighborhood Hits	79
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

MECP2_MOUSE
θ value	2.36792 (rank : 276)	NC score	0.055468 (rank : 602)
Query Neighborhood Hits	451	Target Neighborhood Hits	76	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Z2D6	Gene names	Mecp2
Domain Architecture
Description	Methyl-CpG-binding protein 2 (MeCP-2 protein) (MeCP2).

MNT_MOUSE
θ value	2.36792 (rank : 277)	NC score	0.099846 (rank : 276)
Query Neighborhood Hits	451	Target Neighborhood Hits	432	Shared Neighborhood Hits	80
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MS3L1_HUMAN
θ value	2.36792 (rank : 278)	NC score	0.049979 (rank : 685)
Query Neighborhood Hits	451	Target Neighborhood Hits	60	Shared Neighborhood Hits	13
SwissProt Accessions	Q8N5Y2, Q9UG70, Q9Y5Z8	Gene names	MSL3L1
Domain Architecture
Description	Male-specific lethal 3-like 1 (MSL3-like 1) (Male-specific lethal-3 homolog 1).

MYCB2_MOUSE
θ value	2.36792 (rank : 279)	NC score	0.041676 (rank : 699)
Query Neighborhood Hits	451	Target Neighborhood Hits	307	Shared Neighborhood Hits	33
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

NU214_HUMAN
θ value	2.36792 (rank : 280)	NC score	0.109961 (rank : 235)
Query Neighborhood Hits	451	Target Neighborhood Hits	657	Shared Neighborhood Hits	82
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

PCD15_HUMAN
θ value	2.36792 (rank : 281)	NC score	0.029536 (rank : 739)
Query Neighborhood Hits	451	Target Neighborhood Hits	289	Shared Neighborhood Hits	37
SwissProt Accessions	Q96QU1, Q96QT8	Gene names	PCDH15
Domain Architecture
Description	Protocadherin-15 precursor.

SMR1_MOUSE
θ value	2.36792 (rank : 282)	NC score	0.145545 (rank : 147)
Query Neighborhood Hits	451	Target Neighborhood Hits	103	Shared Neighborhood Hits	41
SwissProt Accessions	Q61900	Gene names	Smr1, Msg1
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 1 precursor (Salivary protein MSG1).

SOS1_HUMAN
θ value	2.36792 (rank : 283)	NC score	0.039082 (rank : 706)
Query Neighborhood Hits	451	Target Neighborhood Hits	274	Shared Neighborhood Hits	39
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

SPN90_MOUSE
θ value	2.36792 (rank : 284)	NC score	0.038904 (rank : 707)
Query Neighborhood Hits	451	Target Neighborhood Hits	157	Shared Neighborhood Hits	16
SwissProt Accessions	Q9ESJ4, Q68G72	Gene names	Nckipsd, Spin90, Wasbp
Domain Architecture	No domain graphic available
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (N-WASP-interacting protein, 90kDa) (Wiskott-Aldrich syndrome protein-binding protein WISH) (N-WASP-binding protein).

SPR1A_HUMAN
θ value	2.36792 (rank : 285)	NC score	0.095696 (rank : 299)
Query Neighborhood Hits	451	Target Neighborhood Hits	136	Shared Neighborhood Hits	41
SwissProt Accessions	P35321, Q9UDG4	Gene names	SPRR1A
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein IA) (SPR-IA) (SPRK) (19 kDa pancornulin).

SYN1_HUMAN
θ value	2.36792 (rank : 286)	NC score	0.095183 (rank : 301)
Query Neighborhood Hits	451	Target Neighborhood Hits	419	Shared Neighborhood Hits	87
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

TBCD4_MOUSE
θ value	2.36792 (rank : 287)	NC score	0.019731 (rank : 783)
Query Neighborhood Hits	451	Target Neighborhood Hits	276	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BYJ6, Q5DU23, Q66JU2, Q6P2M2, Q8BMH6, Q8BXM2	Gene names	Tbc1d4, Kiaa0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

ZIM10_HUMAN
θ value	2.36792 (rank : 288)	NC score	0.099428 (rank : 277)
Query Neighborhood Hits	451	Target Neighborhood Hits	577	Shared Neighborhood Hits	130
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

AATK_HUMAN
θ value	3.0926 (rank : 289)	NC score	0.034026 (rank : 725)
Query Neighborhood Hits	451	Target Neighborhood Hits	1243	Shared Neighborhood Hits	147
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

BSN_MOUSE
θ value	3.0926 (rank : 290)	NC score	0.238434 (rank : 37)
Query Neighborhood Hits	451	Target Neighborhood Hits	2057	Shared Neighborhood Hits	285
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CC14B_MOUSE
θ value	3.0926 (rank : 291)	NC score	0.013425 (rank : 815)
Query Neighborhood Hits	451	Target Neighborhood Hits	103	Shared Neighborhood Hits	3
SwissProt Accessions	Q6PFY9, Q80WC4, Q8BLV5	Gene names	Cdc14b
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

CENB1_HUMAN
θ value	3.0926 (rank : 292)	NC score	0.020914 (rank : 778)
Query Neighborhood Hits	451	Target Neighborhood Hits	383	Shared Neighborhood Hits	17
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

CRTC1_HUMAN
θ value	3.0926 (rank : 293)	NC score	0.113108 (rank : 225)
Query Neighborhood Hits	451	Target Neighborhood Hits	319	Shared Neighborhood Hits	97
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

DEMA_MOUSE
θ value	3.0926 (rank : 294)	NC score	0.021423 (rank : 771)
Query Neighborhood Hits	451	Target Neighborhood Hits	44	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WV69	Gene names	Epb49, Epb4.9
Domain Architecture
Description	Dematin (Erythrocyte membrane protein band 4.9).

ELL_MOUSE
θ value	3.0926 (rank : 295)	NC score	0.032994 (rank : 730)
Query Neighborhood Hits	451	Target Neighborhood Hits	115	Shared Neighborhood Hits	27
SwissProt Accessions	O08856	Gene names	Ell
Domain Architecture
Description	RNA polymerase II elongation factor ELL (Eleven-nineteen lysine-rich leukemia protein).

ETV5_MOUSE
θ value	3.0926 (rank : 296)	NC score	0.048990 (rank : 688)
Query Neighborhood Hits	451	Target Neighborhood Hits	328	Shared Neighborhood Hits	83
SwissProt Accessions	Q9CXC9, Q3TG49, Q8C0F3, Q9JHB1	Gene names	Etv5
Domain Architecture	No domain graphic available
Description	ETS translocation variant 5.

FOXJ3_HUMAN
θ value	3.0926 (rank : 297)	NC score	0.016265 (rank : 796)
Query Neighborhood Hits	451	Target Neighborhood Hits	177	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UPW0, Q9NSS7	Gene names	FOXJ3, KIAA1041
Domain Architecture
Description	Forkhead box protein J3.

IL4RA_HUMAN
θ value	3.0926 (rank : 298)	NC score	0.045044 (rank : 694)
Query Neighborhood Hits	451	Target Neighborhood Hits	144	Shared Neighborhood Hits	32
SwissProt Accessions	P24394, Q96P01, Q9H181, Q9H182, Q9H183, Q9H184, Q9H185, Q9H186, Q9H187, Q9H188	Gene names	IL4R, 582J2.1, IL4RA
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (sIL4Ralpha/prot) (IL-4-binding protein) (IL4-BP)].

K0460_MOUSE
θ value	3.0926 (rank : 299)	NC score	0.088509 (rank : 332)
Query Neighborhood Hits	451	Target Neighborhood Hits	374	Shared Neighborhood Hits	59
SwissProt Accessions	Q6NXI6, Q3U3L8, Q6ZQA7	Gene names	Kiaa0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

K1802_HUMAN
θ value	3.0926 (rank : 300)	NC score	0.171148 (rank : 98)
Query Neighborhood Hits	451	Target Neighborhood Hits	1378	Shared Neighborhood Hits	204
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

LRP4_HUMAN
θ value	3.0926 (rank : 301)	NC score	0.003876 (rank : 844)
Query Neighborhood Hits	451	Target Neighborhood Hits	355	Shared Neighborhood Hits	7
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

M3K1_MOUSE
θ value	3.0926 (rank : 302)	NC score	0.008779 (rank : 828)
Query Neighborhood Hits	451	Target Neighborhood Hits	952	Shared Neighborhood Hits	42
SwissProt Accessions	P53349, Q60831, Q9R0U3, Q9R256	Gene names	Map3k1, Mekk, Mekk1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1).

MBB1A_MOUSE
θ value	3.0926 (rank : 303)	NC score	0.077382 (rank : 390)
Query Neighborhood Hits	451	Target Neighborhood Hits	233	Shared Neighborhood Hits	46
SwissProt Accessions	Q7TPV4, O35851, Q80Y66, Q8R4X2, Q99KP0	Gene names	Mybbp1a, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A (Myb-binding protein of 160 kDa).

MKL1_HUMAN
θ value	3.0926 (rank : 304)	NC score	0.057488 (rank : 570)
Query Neighborhood Hits	451	Target Neighborhood Hits	232	Shared Neighborhood Hits	46
SwissProt Accessions	Q969V6, Q8TCL1, Q96SC5, Q96SC6, Q9P2B0	Gene names	MKL1, KIAA1438, MAL
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein) (Megakaryocytic acute leukemia protein).

NOS3_HUMAN
θ value	3.0926 (rank : 305)	NC score	0.016097 (rank : 797)
Query Neighborhood Hits	451	Target Neighborhood Hits	59	Shared Neighborhood Hits	21
SwissProt Accessions	P29474, Q13662, Q14251, Q14434	Gene names	NOS3
Domain Architecture
Description	Nitric-oxide synthase, endothelial (EC 1.14.13.39) (EC-NOS) (NOS type III) (NOSIII) (Endothelial NOS) (eNOS) (Constitutive NOS) (cNOS).

NRBP_HUMAN
θ value	3.0926 (rank : 306)	NC score	0.023507 (rank : 762)
Query Neighborhood Hits	451	Target Neighborhood Hits	448	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UHY1, Q53FZ5, Q96SU3	Gene names	NRBP1, BCON3, NRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor-binding protein.

NRBP_MOUSE
θ value	3.0926 (rank : 307)	NC score	0.023660 (rank : 760)
Query Neighborhood Hits	451	Target Neighborhood Hits	442	Shared Neighborhood Hits	19
SwissProt Accessions	Q99J45, Q8BL77	Gene names	Nrbp1, Madm, Nrbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor-binding protein (MLF1 adapter molecule) (HLS7- interacting protein kinase).

PLS4_HUMAN
θ value	3.0926 (rank : 308)	NC score	0.022270 (rank : 768)
Query Neighborhood Hits	451	Target Neighborhood Hits	34	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NRQ2, Q7Z505	Gene names	PLSCR4
Domain Architecture
Description	Phospholipid scramblase 4 (PL scramblase 4) (Ca(2+)-dependent phospholipid scramblase 4) (TRA1).

PPRB_MOUSE
θ value	3.0926 (rank : 309)	NC score	0.079665 (rank : 371)
Query Neighborhood Hits	451	Target Neighborhood Hits	354	Shared Neighborhood Hits	68
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

PS1C2_HUMAN
θ value	3.0926 (rank : 310)	NC score	0.152789 (rank : 129)
Query Neighborhood Hits	451	Target Neighborhood Hits	66	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UIG4	Gene names	PSORS1C2, C6orf17, SPR1
Domain Architecture	No domain graphic available
Description	Psoriasis susceptibility 1 candidate gene 2 protein precursor (SPR1 protein).

RBM12_MOUSE
θ value	3.0926 (rank : 311)	NC score	0.093445 (rank : 308)
Query Neighborhood Hits	451	Target Neighborhood Hits	313	Shared Neighborhood Hits	50
SwissProt Accessions	Q8R4X3, Q8K373, Q8R302, Q9CS80	Gene names	Rbm12
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

RL1D1_HUMAN
θ value	3.0926 (rank : 312)	NC score	0.110286 (rank : 231)
Query Neighborhood Hits	451	Target Neighborhood Hits	180	Shared Neighborhood Hits	45
SwissProt Accessions	O76021, Q6PL22, Q8IWS7, Q8WUZ1, Q9HDA9, Q9Y3Z9	Gene names	RSL1D1, CATX11, CSIG, PBK1
Domain Architecture	No domain graphic available
Description	Ribosomal L1 domain-containing protein 1 (Cellular senescence- inhibited gene protein) (Protein PBK1) (CATX-11).

SELPL_MOUSE
θ value	3.0926 (rank : 313)	NC score	0.216029 (rank : 45)
Query Neighborhood Hits	451	Target Neighborhood Hits	588	Shared Neighborhood Hits	152
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SFPQ_HUMAN
θ value	3.0926 (rank : 314)	NC score	0.109322 (rank : 238)
Query Neighborhood Hits	451	Target Neighborhood Hits	986	Shared Neighborhood Hits	115
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

SFR11_HUMAN
θ value	3.0926 (rank : 315)	NC score	0.106837 (rank : 250)
Query Neighborhood Hits	451	Target Neighborhood Hits	246	Shared Neighborhood Hits	38
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

SH3K1_MOUSE
θ value	3.0926 (rank : 316)	NC score	0.037481 (rank : 714)
Query Neighborhood Hits	451	Target Neighborhood Hits	332	Shared Neighborhood Hits	35
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

SMC3_HUMAN
θ value	3.0926 (rank : 317)	NC score	0.025290 (rank : 758)
Query Neighborhood Hits	451	Target Neighborhood Hits	1186	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

SMC3_MOUSE
θ value	3.0926 (rank : 318)	NC score	0.025443 (rank : 755)
Query Neighborhood Hits	451	Target Neighborhood Hits	1187	Shared Neighborhood Hits	61
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

SMN_MOUSE
θ value	3.0926 (rank : 319)	NC score	0.041379 (rank : 702)
Query Neighborhood Hits	451	Target Neighborhood Hits	29	Shared Neighborhood Hits	8
SwissProt Accessions	P97801, O09092	Gene names	Smn1, Smn
Domain Architecture
Description	Survival motor neuron protein.

SREC2_MOUSE
θ value	3.0926 (rank : 320)	NC score	0.025507 (rank : 753)
Query Neighborhood Hits	451	Target Neighborhood Hits	605	Shared Neighborhood Hits	45
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

TCF19_MOUSE
θ value	3.0926 (rank : 321)	NC score	0.027720 (rank : 745)
Query Neighborhood Hits	451	Target Neighborhood Hits	27	Shared Neighborhood Hits	5
SwissProt Accessions	Q99KJ5, Q8BPA3, Q9CT93	Gene names	Tcf19, Sc1
Domain Architecture
Description	Transcription factor 19-like protein (SC1 protein homolog).

TF3C2_MOUSE
θ value	3.0926 (rank : 322)	NC score	0.037035 (rank : 716)
Query Neighborhood Hits	451	Target Neighborhood Hits	165	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BL74, Q3U7Z9, Q80XQ7, Q8BJJ4, Q8BLP3, Q8K1J1, Q9CSS0, Q9CVE6, Q9DBK6	Gene names	Gtf3c2, Kiaa0011
Domain Architecture
Description	General transcription factor 3C polypeptide 2 (Transcription factor IIIC-subunit beta) (TF3C-beta) (TFIIIC 110 kDa subunit) (TFIIIC110).

TNK1_HUMAN
θ value	3.0926 (rank : 323)	NC score	0.003943 (rank : 843)
Query Neighborhood Hits	451	Target Neighborhood Hits	815	Shared Neighborhood Hits	37
SwissProt Accessions	Q13470, O95364, Q8IYI4	Gene names	TNK1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1).

TOP1_MOUSE
θ value	3.0926 (rank : 324)	NC score	0.037117 (rank : 715)
Query Neighborhood Hits	451	Target Neighborhood Hits	213	Shared Neighborhood Hits	24
SwissProt Accessions	Q04750	Gene names	Top1, Top-1
Domain Architecture
Description	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I).

WASP_MOUSE
θ value	3.0926 (rank : 325)	NC score	0.147484 (rank : 141)
Query Neighborhood Hits	451	Target Neighborhood Hits	223	Shared Neighborhood Hits	63
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

ZIM10_MOUSE
θ value	3.0926 (rank : 326)	NC score	0.069191 (rank : 456)
Query Neighborhood Hits	451	Target Neighborhood Hits	430	Shared Neighborhood Hits	91
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

CD2L7_HUMAN
θ value	4.03905 (rank : 327)	NC score	0.029589 (rank : 738)
Query Neighborhood Hits	451	Target Neighborhood Hits	1275	Shared Neighborhood Hits	120
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

CDT1_MOUSE
θ value	4.03905 (rank : 328)	NC score	0.047796 (rank : 690)
Query Neighborhood Hits	451	Target Neighborhood Hits	72	Shared Neighborhood Hits	19
SwissProt Accessions	Q8R4E9, Q8BUQ1, Q8BX29, Q8R3V0, Q8R4E8	Gene names	Cdt1, Ris2
Domain Architecture	No domain graphic available
Description	DNA replication factor Cdt1 (Double parked homolog) (DUP) (Retroviral insertion site 2 protein).

DHX29_HUMAN
θ value	4.03905 (rank : 329)	NC score	0.007171 (rank : 833)
Query Neighborhood Hits	451	Target Neighborhood Hits	144	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z478, O75549, Q63HN0, Q63HN3, Q8IWW2, Q8N3A1, Q9UMH2	Gene names	DHX29
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX29 (EC 3.6.1.-) (DEAH box protein 29) (Nucleic acid helicase DDXx).

EMIL2_MOUSE
θ value	4.03905 (rank : 330)	NC score	0.024811 (rank : 759)
Query Neighborhood Hits	451	Target Neighborhood Hits	485	Shared Neighborhood Hits	36
SwissProt Accessions	Q8K482	Gene names	Emilin2
Domain Architecture
Description	EMILIN-2 precursor (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Basilin).

FMNL_MOUSE
θ value	4.03905 (rank : 331)	NC score	0.132597 (rank : 172)
Query Neighborhood Hits	451	Target Neighborhood Hits	428	Shared Neighborhood Hits	71
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

GLUD1_MOUSE
θ value	4.03905 (rank : 332)	NC score	0.022755 (rank : 765)
Query Neighborhood Hits	451	Target Neighborhood Hits	23	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CIX8	Gene names	Gluld1, Lgs
Domain Architecture	No domain graphic available
Description	Glutamate--ammonia ligase domain-containing protein 1 (Lengsin) (Lens glutamine synthase-like).

K1543_MOUSE
θ value	4.03905 (rank : 333)	NC score	0.154696 (rank : 126)
Query Neighborhood Hits	451	Target Neighborhood Hits	497	Shared Neighborhood Hits	135
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

K2C6B_MOUSE
θ value	4.03905 (rank : 334)	NC score	0.011098 (rank : 823)
Query Neighborhood Hits	451	Target Neighborhood Hits	506	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Z331	Gene names	Krt6b, K6-beta, Krt2-6b
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK 6B) (K6b keratin) (Keratin-6 beta) (mK6-beta).

KS6B2_MOUSE
θ value	4.03905 (rank : 335)	NC score	0.003981 (rank : 842)
Query Neighborhood Hits	451	Target Neighborhood Hits	871	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Z1M4	Gene names	Rps6kb2
Domain Architecture
Description	Ribosomal protein S6 kinase beta-2 (EC 2.7.11.1) (S6K-beta 2) (70 kDa ribosomal protein S6 kinase 2) (p70-S6KB) (p70 ribosomal S6 kinase beta) (p70 S6Kbeta) (S6K2).

MAST4_HUMAN
θ value	4.03905 (rank : 336)	NC score	0.062771 (rank : 508)
Query Neighborhood Hits	451	Target Neighborhood Hits	1804	Shared Neighborhood Hits	215
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

MYST3_MOUSE
θ value	4.03905 (rank : 337)	NC score	0.078304 (rank : 377)
Query Neighborhood Hits	451	Target Neighborhood Hits	688	Shared Neighborhood Hits	94
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

NFM_HUMAN
θ value	4.03905 (rank : 338)	NC score	0.056721 (rank : 585)
Query Neighborhood Hits	451	Target Neighborhood Hits	1328	Shared Neighborhood Hits	125
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

PLCB3_MOUSE
θ value	4.03905 (rank : 339)	NC score	0.021182 (rank : 775)
Query Neighborhood Hits	451	Target Neighborhood Hits	344	Shared Neighborhood Hits	27
SwissProt Accessions	P51432	Gene names	Plcb3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

PROP1_MOUSE
θ value	4.03905 (rank : 340)	NC score	0.023018 (rank : 764)
Query Neighborhood Hits	451	Target Neighborhood Hits	361	Shared Neighborhood Hits	19
SwissProt Accessions	P97458	Gene names	Prop1, Prop-1
Domain Architecture
Description	Homeobox protein prophet of Pit-1 (PROP-1) (Pituitary-specific homeodomain factor).

RCOR2_MOUSE
θ value	4.03905 (rank : 341)	NC score	0.060237 (rank : 531)
Query Neighborhood Hits	451	Target Neighborhood Hits	107	Shared Neighborhood Hits	26
SwissProt Accessions	Q8C796, Q9JMK4	Gene names	Rcor2
Domain Architecture	No domain graphic available
Description	REST corepressor 2 (M-CoREST).

SF3B2_HUMAN
θ value	4.03905 (rank : 342)	NC score	0.058009 (rank : 567)
Query Neighborhood Hits	451	Target Neighborhood Hits	157	Shared Neighborhood Hits	26
SwissProt Accessions	Q13435	Gene names	SF3B2, SAP145
Domain Architecture
Description	Splicing factor 3B subunit 2 (Spliceosome-associated protein 145) (SAP 145) (SF3b150) (Pre-mRNA-splicing factor SF3b 145 kDa subunit).

SFRS2_HUMAN
θ value	4.03905 (rank : 343)	NC score	0.025320 (rank : 756)
Query Neighborhood Hits	451	Target Neighborhood Hits	222	Shared Neighborhood Hits	19
SwissProt Accessions	Q01130	Gene names	SFRS2
Domain Architecture
Description	Splicing factor, arginine/serine-rich 2 (Splicing factor SC35) (SC-35) (Splicing component, 35 kDa) (Protein PR264).

SFRS2_MOUSE
θ value	4.03905 (rank : 344)	NC score	0.025320 (rank : 757)
Query Neighborhood Hits	451	Target Neighborhood Hits	222	Shared Neighborhood Hits	19
SwissProt Accessions	Q62093, Q542L3, Q60701	Gene names	Sfrs2, Pr264, Sfrs10
Domain Architecture
Description	Splicing factor, arginine/serine-rich 2 (Splicing factor SC35) (SC-35) (Splicing component, 35 kDa) (Protein PR264) (Putative myelin regulatory factor 1) (MRF-1).

SOX9_HUMAN
θ value	4.03905 (rank : 345)	NC score	0.026176 (rank : 750)
Query Neighborhood Hits	451	Target Neighborhood Hits	210	Shared Neighborhood Hits	46
SwissProt Accessions	P48436	Gene names	SOX9
Domain Architecture
Description	Transcription factor SOX-9.

TARA_HUMAN
θ value	4.03905 (rank : 346)	NC score	0.209212 (rank : 52)
Query Neighborhood Hits	451	Target Neighborhood Hits	1626	Shared Neighborhood Hits	211
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

USH1C_MOUSE
θ value	4.03905 (rank : 347)	NC score	0.033198 (rank : 727)
Query Neighborhood Hits	451	Target Neighborhood Hits	557	Shared Neighborhood Hits	46
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

YETS2_HUMAN
θ value	4.03905 (rank : 348)	NC score	0.059051 (rank : 550)
Query Neighborhood Hits	451	Target Neighborhood Hits	212	Shared Neighborhood Hits	46
SwissProt Accessions	Q9ULM3, Q641P6, Q9NW96	Gene names	YEATS2, KIAA1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

3BP2_MOUSE
θ value	5.27518 (rank : 349)	NC score	0.046971 (rank : 691)
Query Neighborhood Hits	451	Target Neighborhood Hits	142	Shared Neighborhood Hits	24
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

ABI3_MOUSE
θ value	5.27518 (rank : 350)	NC score	0.062758 (rank : 509)
Query Neighborhood Hits	451	Target Neighborhood Hits	227	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

CABP4_MOUSE
θ value	5.27518 (rank : 351)	NC score	0.008019 (rank : 829)
Query Neighborhood Hits	451	Target Neighborhood Hits	212	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VHC5	Gene names	Cabp4
Domain Architecture	No domain graphic available
Description	Calcium-binding protein 4 (CaBP4).

CITE4_HUMAN
θ value	5.27518 (rank : 352)	NC score	0.060206 (rank : 535)
Query Neighborhood Hits	451	Target Neighborhood Hits	67	Shared Neighborhood Hits	26
SwissProt Accessions	Q96RK1	Gene names	CITED4, MRG2
Domain Architecture	No domain graphic available
Description	Cbp/p300-interacting transactivator 4 (MSG1-related protein 2) (MRG- 2).

CJ108_HUMAN
θ value	5.27518 (rank : 353)	NC score	0.126011 (rank : 186)
Query Neighborhood Hits	451	Target Neighborhood Hits	165	Shared Neighborhood Hits	71
SwissProt Accessions	Q8N8Z3	Gene names	C10orf108
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C10orf108.

CTRO_HUMAN
θ value	5.27518 (rank : 354)	NC score	0.015856 (rank : 798)
Query Neighborhood Hits	451	Target Neighborhood Hits	2092	Shared Neighborhood Hits	107
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

CTRO_MOUSE
θ value	5.27518 (rank : 355)	NC score	0.017645 (rank : 788)
Query Neighborhood Hits	451	Target Neighborhood Hits	2344	Shared Neighborhood Hits	114
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

DDEF1_MOUSE
θ value	5.27518 (rank : 356)	NC score	0.060231 (rank : 532)
Query Neighborhood Hits	451	Target Neighborhood Hits	592	Shared Neighborhood Hits	74
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

DIDO1_HUMAN
θ value	5.27518 (rank : 357)	NC score	0.144773 (rank : 152)
Query Neighborhood Hits	451	Target Neighborhood Hits	960	Shared Neighborhood Hits	155
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

DNJC4_MOUSE
θ value	5.27518 (rank : 358)	NC score	0.009609 (rank : 826)
Query Neighborhood Hits	451	Target Neighborhood Hits	79	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D844, O70278	Gene names	Dnajc4, Mcg18
Domain Architecture
Description	DnaJ homolog subfamily C member 4 (Multiple endocrine neoplasia type 1 candidate protein number 18 homolog).

DPOLL_HUMAN
θ value	5.27518 (rank : 359)	NC score	0.015734 (rank : 799)
Query Neighborhood Hits	451	Target Neighborhood Hits	26	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UGP5, Q5JQP5, Q6NUM2, Q9HA10, Q9HB35	Gene names	POLL
Domain Architecture
Description	DNA polymerase lambda (EC 2.7.7.7) (EC 4.2.99.-) (Pol Lambda) (DNA polymerase kappa) (DNA polymerase beta-2) (Pol beta2).

DVL2_HUMAN
θ value	5.27518 (rank : 360)	NC score	0.017381 (rank : 790)
Query Neighborhood Hits	451	Target Neighborhood Hits	223	Shared Neighborhood Hits	23
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

G3PT_MOUSE
θ value	5.27518 (rank : 361)	NC score	0.059450 (rank : 545)
Query Neighborhood Hits	451	Target Neighborhood Hits	78	Shared Neighborhood Hits	34
SwissProt Accessions	Q64467, Q60650	Gene names	Gapdhs, Gapd-s, Gapds
Domain Architecture
Description	Glyceraldehyde-3-phosphate dehydrogenase, testis-specific (EC 1.2.1.12) (Spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2) (GAPDH-2).

GDF5_HUMAN
θ value	5.27518 (rank : 362)	NC score	0.007155 (rank : 834)
Query Neighborhood Hits	451	Target Neighborhood Hits	103	Shared Neighborhood Hits	14
SwissProt Accessions	P43026, Q96SB1	Gene names	GDF5, CDMP1
Domain Architecture
Description	Growth/differentiation factor 5 precursor (GDF-5) (Cartilage-derived morphogenetic protein 1) (CDMP-1) (Radotermin).

HCN1_MOUSE
θ value	5.27518 (rank : 363)	NC score	0.007799 (rank : 830)
Query Neighborhood Hits	451	Target Neighborhood Hits	172	Shared Neighborhood Hits	15
SwissProt Accessions	O88704, O54899, Q9D613	Gene names	Hcn1, Bcng1, Hac2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1) (Hyperpolarization-activated cation channel 2) (HAC-2).

ICK_HUMAN
θ value	5.27518 (rank : 364)	NC score	0.007457 (rank : 832)
Query Neighborhood Hits	451	Target Neighborhood Hits	867	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UPZ9, O75985, Q5THL2, Q8IYH8, Q9BX17, Q9NYX3	Gene names	ICK, KIAA0936
Domain Architecture
Description	Serine/threonine-protein kinase ICK (EC 2.7.11.22) (Intestinal cell kinase) (hICK) (MAK-related kinase) (MRK) (Laryngeal cancer kinase 2) (LCK2).

IQEC3_HUMAN
θ value	5.27518 (rank : 365)	NC score	0.029001 (rank : 741)
Query Neighborhood Hits	451	Target Neighborhood Hits	125	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UPP2, Q8TB43	Gene names	IQSEC3, KIAA1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

MINT_MOUSE
θ value	5.27518 (rank : 366)	NC score	0.184713 (rank : 82)
Query Neighborhood Hits	451	Target Neighborhood Hits	1514	Shared Neighborhood Hits	250
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MYH14_MOUSE
θ value	5.27518 (rank : 367)	NC score	0.013462 (rank : 814)
Query Neighborhood Hits	451	Target Neighborhood Hits	1225	Shared Neighborhood Hits	48
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

NMDE4_MOUSE
θ value	5.27518 (rank : 368)	NC score	0.014655 (rank : 807)
Query Neighborhood Hits	451	Target Neighborhood Hits	158	Shared Neighborhood Hits	30
SwissProt Accessions	Q03391	Gene names	Grin2d
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D).

NPAS2_MOUSE
θ value	5.27518 (rank : 369)	NC score	0.014751 (rank : 805)
Query Neighborhood Hits	451	Target Neighborhood Hits	132	Shared Neighborhood Hits	15
SwissProt Accessions	P97460	Gene names	Npas2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2).

OST4_HUMAN
θ value	5.27518 (rank : 370)	NC score	0.014572 (rank : 808)
Query Neighborhood Hits	451	Target Neighborhood Hits	95	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y661, Q5QI42, Q8NDC2	Gene names	HS3ST4, 3OST4
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 4 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4) (Heparan sulfate 3-O-sulfotransferase 4) (h3-OST-4).

PHF13_MOUSE
θ value	5.27518 (rank : 371)	NC score	0.026461 (rank : 748)
Query Neighborhood Hits	451	Target Neighborhood Hits	42	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K2W6	Gene names	Phf13
Domain Architecture
Description	PHD finger protein 13.

PKN3_HUMAN
θ value	5.27518 (rank : 372)	NC score	0.004784 (rank : 841)
Query Neighborhood Hits	451	Target Neighborhood Hits	893	Shared Neighborhood Hits	41
SwissProt Accessions	Q6P5Z2, Q9UM03	Gene names	PKN3, PKNBETA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

PP16A_HUMAN
θ value	5.27518 (rank : 373)	NC score	0.013603 (rank : 812)
Query Neighborhood Hits	451	Target Neighborhood Hits	340	Shared Neighborhood Hits	21
SwissProt Accessions	Q96I34	Gene names	PPP1R16A, MYPT3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase- targeting subunit 3).

PRP1_HUMAN
θ value	5.27518 (rank : 374)	NC score	0.184333 (rank : 83)
Query Neighborhood Hits	451	Target Neighborhood Hits	385	Shared Neighborhood Hits	86
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

SF3A1_MOUSE
θ value	5.27518 (rank : 375)	NC score	0.097890 (rank : 286)
Query Neighborhood Hits	451	Target Neighborhood Hits	198	Shared Neighborhood Hits	43
SwissProt Accessions	Q8K4Z5, Q8C0M7, Q8C128, Q8C175, Q921T3	Gene names	Sf3a1
Domain Architecture	No domain graphic available
Description	Splicing factor 3 subunit 1 (SF3a120).

SMN_HUMAN
θ value	5.27518 (rank : 376)	NC score	0.045423 (rank : 692)
Query Neighborhood Hits	451	Target Neighborhood Hits	39	Shared Neighborhood Hits	11
SwissProt Accessions	Q16637, Q13119, Q96J51	Gene names	SMN1, SMN, SMNT
Domain Architecture
Description	Survival motor neuron protein (Component of gems 1) (Gemin-1).

SNPH_HUMAN
θ value	5.27518 (rank : 377)	NC score	0.028752 (rank : 742)
Query Neighborhood Hits	451	Target Neighborhood Hits	236	Shared Neighborhood Hits	27
SwissProt Accessions	O15079	Gene names	SNPH, KIAA0374
Domain Architecture	No domain graphic available
Description	Syntaphilin.

SOS1_MOUSE
θ value	5.27518 (rank : 378)	NC score	0.038740 (rank : 709)
Query Neighborhood Hits	451	Target Neighborhood Hits	281	Shared Neighborhood Hits	42
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

SYT6_HUMAN
θ value	5.27518 (rank : 379)	NC score	0.015013 (rank : 804)
Query Neighborhood Hits	451	Target Neighborhood Hits	138	Shared Neighborhood Hits	9
SwissProt Accessions	Q5T7P8	Gene names	SYT6
Domain Architecture	No domain graphic available
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

UBP21_HUMAN
θ value	5.27518 (rank : 380)	NC score	0.021261 (rank : 774)
Query Neighborhood Hits	451	Target Neighborhood Hits	95	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UK80, Q9BTV1, Q9NYN4	Gene names	USP21, USP23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21) (NEDD8-specific protease).

VCY1_HUMAN
θ value	5.27518 (rank : 381)	NC score	0.105421 (rank : 253)
Query Neighborhood Hits	451	Target Neighborhood Hits	38	Shared Neighborhood Hits	9
SwissProt Accessions	O14598	Gene names	VCY, BPY1
Domain Architecture	No domain graphic available
Description	Testis-specific basic protein Y 1 (Variably charged protein Y).

WNK4_MOUSE
θ value	5.27518 (rank : 382)	NC score	0.020236 (rank : 781)
Query Neighborhood Hits	451	Target Neighborhood Hits	961	Shared Neighborhood Hits	68
SwissProt Accessions	Q80UE6, Q4VAC1, Q80XB5, Q80XN2, Q8R0N0, Q8R340	Gene names	Wnk4, Prkwnk4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

ZBTB4_HUMAN
θ value	5.27518 (rank : 383)	NC score	0.010574 (rank : 824)
Query Neighborhood Hits	451	Target Neighborhood Hits	926	Shared Neighborhood Hits	48
SwissProt Accessions	Q9P1Z0, Q7Z697, Q86XJ4, Q8N4V8	Gene names	ZBTB4, KIAA1538
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 4 (KAISO-like zinc finger protein 1) (KAISO-L1).

ZN197_HUMAN
θ value	5.27518 (rank : 384)	NC score	-0.003383 (rank : 850)
Query Neighborhood Hits	451	Target Neighborhood Hits	788	Shared Neighborhood Hits	25
SwissProt Accessions	O14709	Gene names	ZNF197, ZNF166
Domain Architecture
Description	Zinc finger protein 197 (ZnF20).

ACK1_MOUSE
θ value	6.88961 (rank : 385)	NC score	0.021545 (rank : 770)
Query Neighborhood Hits	451	Target Neighborhood Hits	1080	Shared Neighborhood Hits	120
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

ACOT1_HUMAN
θ value	6.88961 (rank : 386)	NC score	0.005860 (rank : 836)
Query Neighborhood Hits	451	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q86TX2, Q3I5F9	Gene names	ACOT1, CTE1
Domain Architecture	No domain graphic available
Description	Acyl-coenzyme A thioesterase 1 (EC 3.1.2.2) (Acyl-CoA thioesterase 1) (Inducible cytosolic acyl-coenzyme A thioester hydrolase) (Long chain acyl-CoA thioester hydrolase) (Long chain acyl-CoA hydrolase) (CTE-I) (CTE-Ib).

ACRO_HUMAN
θ value	6.88961 (rank : 387)	NC score	0.011432 (rank : 822)
Query Neighborhood Hits	451	Target Neighborhood Hits	291	Shared Neighborhood Hits	47
SwissProt Accessions	P10323, Q6ICK2	Gene names	ACR, ACRS
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

AHTF1_MOUSE
θ value	6.88961 (rank : 388)	NC score	0.052108 (rank : 657)
Query Neighborhood Hits	451	Target Neighborhood Hits	176	Shared Neighborhood Hits	41
SwissProt Accessions	Q8CJF7, Q8BVJ5, Q8VD55	Gene names	Ahctf1, Elys
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

CIC_HUMAN
θ value	6.88961 (rank : 389)	NC score	0.148224 (rank : 138)
Query Neighborhood Hits	451	Target Neighborhood Hits	992	Shared Neighborhood Hits	186
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CO027_MOUSE
θ value	6.88961 (rank : 390)	NC score	0.016939 (rank : 791)
Query Neighborhood Hits	451	Target Neighborhood Hits	33	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BZB3, Q6NVG3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf27 homolog.

DEMA_HUMAN
θ value	6.88961 (rank : 391)	NC score	0.020257 (rank : 780)
Query Neighborhood Hits	451	Target Neighborhood Hits	49	Shared Neighborhood Hits	10
SwissProt Accessions	Q08495, Q13215, Q9BRE3	Gene names	EPB49, DMT
Domain Architecture
Description	Dematin (Erythrocyte membrane protein band 4.9).

DLG5_HUMAN
θ value	6.88961 (rank : 392)	NC score	0.034137 (rank : 723)
Query Neighborhood Hits	451	Target Neighborhood Hits	1088	Shared Neighborhood Hits	92
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

FMNL_HUMAN
θ value	6.88961 (rank : 393)	NC score	0.156545 (rank : 124)
Query Neighborhood Hits	451	Target Neighborhood Hits	529	Shared Neighborhood Hits	86
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

GNDS_MOUSE
θ value	6.88961 (rank : 394)	NC score	0.030716 (rank : 734)
Query Neighborhood Hits	451	Target Neighborhood Hits	115	Shared Neighborhood Hits	27
SwissProt Accessions	Q03385	Gene names	Ralgds, Rgds
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator (RalGEF) (RalGDS).

GON4L_HUMAN
θ value	6.88961 (rank : 395)	NC score	0.074680 (rank : 409)
Query Neighborhood Hits	451	Target Neighborhood Hits	555	Shared Neighborhood Hits	88
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

GPR64_HUMAN
θ value	6.88961 (rank : 396)	NC score	0.028523 (rank : 743)
Query Neighborhood Hits	451	Target Neighborhood Hits	207	Shared Neighborhood Hits	32
SwissProt Accessions	Q8IZP9, O00406, Q8IWT2, Q8IZE4, Q8IZE5, Q8IZE6, Q8IZE7, Q8IZP3, Q8IZP4	Gene names	GPR64, HE6, TM7LN2
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (He6 receptor).

GRB10_MOUSE
θ value	6.88961 (rank : 397)	NC score	0.032223 (rank : 732)
Query Neighborhood Hits	451	Target Neighborhood Hits	156	Shared Neighborhood Hits	8
SwissProt Accessions	Q60760, O35352, Q7TSA4, Q8BSH4, Q8BSS5, Q91WC5	Gene names	Grb10
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein).

H10_HUMAN
θ value	6.88961 (rank : 398)	NC score	0.039360 (rank : 705)
Query Neighborhood Hits	451	Target Neighborhood Hits	53	Shared Neighborhood Hits	15
SwissProt Accessions	P07305	Gene names	H1F0, H1FV
Domain Architecture
Description	Histone H1.0 (H1(0)) (Histone H1').

K0460_HUMAN
θ value	6.88961 (rank : 399)	NC score	0.081178 (rank : 362)
Query Neighborhood Hits	451	Target Neighborhood Hits	357	Shared Neighborhood Hits	56
SwissProt Accessions	Q5VT52, O75048, Q5VT53, Q6MZL4, Q86XD2	Gene names	KIAA0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

LR37A_HUMAN
θ value	6.88961 (rank : 400)	NC score	0.167266 (rank : 109)
Query Neighborhood Hits	451	Target Neighborhood Hits	720	Shared Neighborhood Hits	126
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

M3K6_HUMAN
θ value	6.88961 (rank : 401)	NC score	0.007753 (rank : 831)
Query Neighborhood Hits	451	Target Neighborhood Hits	889	Shared Neighborhood Hits	41
SwissProt Accessions	O95382	Gene names	MAP3K6, MAPKKK6
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 6 (EC 2.7.11.25).

MK04_HUMAN
θ value	6.88961 (rank : 402)	NC score	0.005599 (rank : 838)
Query Neighborhood Hits	451	Target Neighborhood Hits	837	Shared Neighborhood Hits	35
SwissProt Accessions	P31152	Gene names	MAPK4, ERK4, PRKM4
Domain Architecture
Description	Mitogen-activated protein kinase 4 (EC 2.7.11.24) (Extracellular signal-regulated kinase 4) (ERK-4) (MAP kinase isoform p63) (p63- MAPK).

NCOA6_MOUSE
θ value	6.88961 (rank : 403)	NC score	0.194402 (rank : 72)
Query Neighborhood Hits	451	Target Neighborhood Hits	1076	Shared Neighborhood Hits	223
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

RCOR2_HUMAN
θ value	6.88961 (rank : 404)	NC score	0.056540 (rank : 589)
Query Neighborhood Hits	451	Target Neighborhood Hits	114	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IZ40, Q96FP3	Gene names	RCOR2
Domain Architecture	No domain graphic available
Description	REST corepressor 2.

RM47_HUMAN
θ value	6.88961 (rank : 405)	NC score	0.016305 (rank : 795)
Query Neighborhood Hits	451	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HD33	Gene names	MRPL47
Domain Architecture
Description	39S ribosomal protein L47, mitochondrial precursor (L47mt) (MRP-L47).

SMR3B_HUMAN
θ value	6.88961 (rank : 406)	NC score	0.072244 (rank : 432)
Query Neighborhood Hits	451	Target Neighborhood Hits	46	Shared Neighborhood Hits	21
SwissProt Accessions	P02814, Q9UBN0, Q9UCT0	Gene names	SMR3B, PBII, PROL3
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog B precursor (Proline-rich protein 3) (Proline-rich peptide P-B) [Contains: Peptide P-A; Peptide D1A].

TNIK_HUMAN
θ value	6.88961 (rank : 407)	NC score	0.013414 (rank : 816)
Query Neighborhood Hits	451	Target Neighborhood Hits	1570	Shared Neighborhood Hits	101
SwissProt Accessions	Q9UKE5, O60298, Q8WUY7, Q9UKD8, Q9UKD9, Q9UKE0, Q9UKE1, Q9UKE2, Q9UKE3, Q9UKE4	Gene names	TNIK, KIAA0551
Domain Architecture
Description	TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1).

ABI3_HUMAN
θ value	8.99809 (rank : 408)	NC score	0.051022 (rank : 674)
Query Neighborhood Hits	451	Target Neighborhood Hits	227	Shared Neighborhood Hits	37
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

AIRE_MOUSE
θ value	8.99809 (rank : 409)	NC score	0.042863 (rank : 698)
Query Neighborhood Hits	451	Target Neighborhood Hits	196	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

AL2S4_MOUSE
θ value	8.99809 (rank : 410)	NC score	0.091481 (rank : 317)
Query Neighborhood Hits	451	Target Neighborhood Hits	193	Shared Neighborhood Hits	62
SwissProt Accessions	Q3V0J1, Q3TIS2	Gene names	Als2cr4
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein homolog.

AZI1_HUMAN
θ value	8.99809 (rank : 411)	NC score	0.025906 (rank : 751)
Query Neighborhood Hits	451	Target Neighborhood Hits	1000	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

CD2L5_MOUSE
θ value	8.99809 (rank : 412)	NC score	0.015562 (rank : 800)
Query Neighborhood Hits	451	Target Neighborhood Hits	1011	Shared Neighborhood Hits	62
SwissProt Accessions	Q69ZA1, Q80V11, Q8BZG1, Q8K0A4	Gene names	Cdc2l5, Kiaa1791
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5).

CIZ1_HUMAN
θ value	8.99809 (rank : 413)	NC score	0.145596 (rank : 146)
Query Neighborhood Hits	451	Target Neighborhood Hits	359	Shared Neighborhood Hits	86
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

CRTC1_MOUSE
θ value	8.99809 (rank : 414)	NC score	0.077482 (rank : 388)
Query Neighborhood Hits	451	Target Neighborhood Hits	230	Shared Neighborhood Hits	62
SwissProt Accessions	Q68ED7, Q6ZQ85	Gene names	Crtc1, Kiaa0616, Mect1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1 homolog).

DAAM1_HUMAN
θ value	8.99809 (rank : 415)	NC score	0.103437 (rank : 264)
Query Neighborhood Hits	451	Target Neighborhood Hits	483	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y4D1, Q86U34, Q8N1Z8, Q8TB39	Gene names	DAAM1, KIAA0666
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

DCC_HUMAN
θ value	8.99809 (rank : 416)	NC score	0.023550 (rank : 761)
Query Neighborhood Hits	451	Target Neighborhood Hits	583	Shared Neighborhood Hits	45
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

DMRTD_HUMAN
θ value	8.99809 (rank : 417)	NC score	0.082515 (rank : 355)
Query Neighborhood Hits	451	Target Neighborhood Hits	216	Shared Neighborhood Hits	83
SwissProt Accessions	Q8IXT2, Q8N6Q2, Q96M39, Q96SD4	Gene names	DMRTC2
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2.

EGR2_HUMAN
θ value	8.99809 (rank : 418)	NC score	-0.000532 (rank : 848)
Query Neighborhood Hits	451	Target Neighborhood Hits	728	Shared Neighborhood Hits	22
SwissProt Accessions	P11161, Q8IV26, Q9UNA6	Gene names	EGR2, KROX20
Domain Architecture	No domain graphic available
Description	Early growth response protein 2 (EGR-2) (Krox-20 protein) (AT591).

ELOA1_MOUSE
θ value	8.99809 (rank : 419)	NC score	0.030488 (rank : 736)
Query Neighborhood Hits	451	Target Neighborhood Hits	152	Shared Neighborhood Hits	25
SwissProt Accessions	Q8CB77, Q80VB2, Q9R0Q5	Gene names	Tceb3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

FA21C_HUMAN
θ value	8.99809 (rank : 420)	NC score	0.049296 (rank : 687)
Query Neighborhood Hits	451	Target Neighborhood Hits	194	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y4E1, Q5SQU4, Q5SQU5, Q7L521, Q9UG79	Gene names	FAM21C, KIAA0592
Domain Architecture	No domain graphic available
Description	Protein FAM21C.

FBX17_HUMAN
θ value	8.99809 (rank : 421)	NC score	0.006259 (rank : 835)
Query Neighborhood Hits	451	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q96EF6, Q96LQ4	Gene names	FBXO17, FBG4, FBX17, FBX26, FBXO26
Domain Architecture
Description	F-box only protein 17 (F-box only protein 26).

FOG1_HUMAN
θ value	8.99809 (rank : 422)	NC score	0.022127 (rank : 769)
Query Neighborhood Hits	451	Target Neighborhood Hits	981	Shared Neighborhood Hits	82
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

GNAS3_MOUSE
θ value	8.99809 (rank : 423)	NC score	0.077819 (rank : 381)
Query Neighborhood Hits	451	Target Neighborhood Hits	84	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z0F1, Q9QXW5, Q9Z0H2	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Neuroendocrine secretory protein 55 (NESP55) [Contains: LHAL tetrapeptide; GPIPIRRH peptide].

H11_HUMAN
θ value	8.99809 (rank : 424)	NC score	0.025686 (rank : 752)
Query Neighborhood Hits	451	Target Neighborhood Hits	51	Shared Neighborhood Hits	13
SwissProt Accessions	Q02539	Gene names	HIST1H1A, H1F1
Domain Architecture
Description	Histone H1.1.

HRX_HUMAN
θ value	8.99809 (rank : 425)	NC score	0.119350 (rank : 211)
Query Neighborhood Hits	451	Target Neighborhood Hits	825	Shared Neighborhood Hits	124
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

K1914_MOUSE
θ value	8.99809 (rank : 426)	NC score	0.033084 (rank : 728)
Query Neighborhood Hits	451	Target Neighborhood Hits	216	Shared Neighborhood Hits	35
SwissProt Accessions	Q5DTU0, Q8BID1, Q8K2G0	Gene names	Kiaa1914
Domain Architecture	No domain graphic available
Description	Protein KIAA1914.

LTBP4_MOUSE
θ value	8.99809 (rank : 427)	NC score	0.021034 (rank : 776)
Query Neighborhood Hits	451	Target Neighborhood Hits	607	Shared Neighborhood Hits	50
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

M3K11_HUMAN
θ value	8.99809 (rank : 428)	NC score	0.012312 (rank : 819)
Query Neighborhood Hits	451	Target Neighborhood Hits	1136	Shared Neighborhood Hits	70
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

MLL3_HUMAN
θ value	8.99809 (rank : 429)	NC score	0.198636 (rank : 65)
Query Neighborhood Hits	451	Target Neighborhood Hits	1644	Shared Neighborhood Hits	254
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MYT1_MOUSE
θ value	8.99809 (rank : 430)	NC score	0.018224 (rank : 786)
Query Neighborhood Hits	451	Target Neighborhood Hits	385	Shared Neighborhood Hits	24
SwissProt Accessions	Q8CFC2, O08995, Q8CFH1	Gene names	Myt1, Kiaa0835, Nzf2
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1 (MyT1) (Neural zinc finger factor 2) (NZF-2).

NF1_HUMAN
θ value	8.99809 (rank : 431)	NC score	0.012261 (rank : 820)
Query Neighborhood Hits	451	Target Neighborhood Hits	56	Shared Neighborhood Hits	4
SwissProt Accessions	P21359, O00662, Q14284, Q14930, Q9UMK3	Gene names	NF1
Domain Architecture
Description	Neurofibromin (Neurofibromatosis-related protein NF-1) [Contains: Neurofibromin truncated].

NF1_MOUSE
θ value	8.99809 (rank : 432)	NC score	0.012201 (rank : 821)
Query Neighborhood Hits	451	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	Q04690, Q61956, Q61957	Gene names	Nf1
Domain Architecture
Description	Neurofibromin (Neurofibromatosis-related protein NF-1).

NSD1_MOUSE
θ value	8.99809 (rank : 433)	NC score	0.084290 (rank : 351)
Query Neighborhood Hits	451	Target Neighborhood Hits	472	Shared Neighborhood Hits	79
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

PLCB1_HUMAN
θ value	8.99809 (rank : 434)	NC score	0.028142 (rank : 744)
Query Neighborhood Hits	451	Target Neighborhood Hits	614	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NQ66, O60325, Q5TFF7, Q5TGC9, Q8IV93, Q9BQW2, Q9H4H2, Q9H8H5, Q9NQ65, Q9NQH9, Q9NTH4, Q9UJP6, Q9UM26	Gene names	PLCB1, KIAA0581
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

PLCB1_MOUSE
θ value	8.99809 (rank : 435)	NC score	0.017967 (rank : 787)
Query Neighborhood Hits	451	Target Neighborhood Hits	531	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Z1B3, Q62075, Q8K5A5, Q8K5A6, Q9Z0E5, Q9Z2T5	Gene names	Plcb1, Plcb
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

RAI1_HUMAN
θ value	8.99809 (rank : 436)	NC score	0.066316 (rank : 485)
Query Neighborhood Hits	451	Target Neighborhood Hits	360	Shared Neighborhood Hits	69
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

RCOR3_HUMAN
θ value	8.99809 (rank : 437)	NC score	0.052120 (rank : 656)
Query Neighborhood Hits	451	Target Neighborhood Hits	161	Shared Neighborhood Hits	37
SwissProt Accessions	Q9P2K3, Q5VT47, Q7L9I5, Q8N5U3, Q9NV83	Gene names	RCOR3, KIAA1343
Domain Architecture	No domain graphic available
Description	REST corepressor 3.

SALL2_HUMAN
θ value	8.99809 (rank : 438)	NC score	0.005710 (rank : 837)
Query Neighborhood Hits	451	Target Neighborhood Hits	835	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y467, Q9Y4G1	Gene names	SALL2, KIAA0360, SAL2
Domain Architecture	No domain graphic available
Description	Sal-like protein 2 (Zinc finger protein SALL2) (HSal2).

SMCA1_HUMAN
θ value	8.99809 (rank : 439)	NC score	0.005526 (rank : 839)
Query Neighborhood Hits	451	Target Neighborhood Hits	105	Shared Neighborhood Hits	11
SwissProt Accessions	P28370, Q5JV41, Q5JV42	Gene names	SMARCA1, SNF2L, SNF2L1
Domain Architecture
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1).

SMCA1_MOUSE
θ value	8.99809 (rank : 440)	NC score	0.005385 (rank : 840)
Query Neighborhood Hits	451	Target Neighborhood Hits	117	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PGB8, Q8BSS1, Q91Y58	Gene names	Smarca1, Snf2l
Domain Architecture	No domain graphic available
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1) (DNA-dependent ATPase SNF2L).

SOX30_MOUSE
θ value	8.99809 (rank : 441)	NC score	0.065849 (rank : 492)
Query Neighborhood Hits	451	Target Neighborhood Hits	374	Shared Neighborhood Hits	110
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

ST5_HUMAN
θ value	8.99809 (rank : 442)	NC score	0.026391 (rank : 749)
Query Neighborhood Hits	451	Target Neighborhood Hits	151	Shared Neighborhood Hits	35
SwissProt Accessions	P78524, P78523, Q16492, Q7KYY2, Q7KZ12, Q8NE12, Q9BQQ6	Gene names	ST5, DENND2B, HTS1
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (HeLa tumor suppression 1) (DENN domain-containing protein 2B).

TF3C1_HUMAN
θ value	8.99809 (rank : 443)	NC score	0.016939 (rank : 792)
Query Neighborhood Hits	451	Target Neighborhood Hits	88	Shared Neighborhood Hits	13
SwissProt Accessions	Q12789, Q12838, Q9Y4W9	Gene names	GTF3C1
Domain Architecture	No domain graphic available
Description	General transcription factor 3C polypeptide 1 (Transcription factor IIIC-subunit alpha) (TF3C-alpha) (TFIIIC 220 kDa subunit) (TFIIIC220) (TFIIIC box B-binding subunit).

THOC2_HUMAN
θ value	8.99809 (rank : 444)	NC score	0.060731 (rank : 528)
Query Neighborhood Hits	451	Target Neighborhood Hits	337	Shared Neighborhood Hits	39
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

TTC16_HUMAN
θ value	8.99809 (rank : 445)	NC score	0.093180 (rank : 311)
Query Neighborhood Hits	451	Target Neighborhood Hits	417	Shared Neighborhood Hits	64
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

UBN1_HUMAN
θ value	8.99809 (rank : 446)	NC score	0.034055 (rank : 724)
Query Neighborhood Hits	451	Target Neighborhood Hits	170	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NPG3, Q13079, Q9P1P7	Gene names	UBN1
Domain Architecture	No domain graphic available
Description	Ubinuclein (Ubiquitously expressed nuclear protein) (VT4).

USP9X_MOUSE
θ value	8.99809 (rank : 447)	NC score	0.014548 (rank : 809)
Query Neighborhood Hits	451	Target Neighborhood Hits	171	Shared Neighborhood Hits	19
SwissProt Accessions	P70398, Q62497	Gene names	Usp9x, Fafl, Fam
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin carboxyl-terminal hydrolase FAM) (Fat facets homolog).

WNK4_HUMAN
θ value	8.99809 (rank : 448)	NC score	0.025452 (rank : 754)
Query Neighborhood Hits	451	Target Neighborhood Hits	1043	Shared Neighborhood Hits	87
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

YLPM1_HUMAN
θ value	8.99809 (rank : 449)	NC score	0.171599 (rank : 95)
Query Neighborhood Hits	451	Target Neighborhood Hits	670	Shared Neighborhood Hits	135
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

ZN619_HUMAN
θ value	8.99809 (rank : 450)	NC score	-0.003845 (rank : 851)
Query Neighborhood Hits	451	Target Neighborhood Hits	749	Shared Neighborhood Hits	19
SwissProt Accessions	Q8N2I2	Gene names	ZNF619
Domain Architecture	No domain graphic available
Description	Zinc finger protein 619.

ZN687_MOUSE
θ value	8.99809 (rank : 451)	NC score	0.015216 (rank : 803)
Query Neighborhood Hits	451	Target Neighborhood Hits	913	Shared Neighborhood Hits	74
SwissProt Accessions	Q9D2D7, Q6PAP3, Q6ZPQ9	Gene names	Znf687, Kiaa1441, Zfp687
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

3BP1_HUMAN
θ value	θ > 10 (rank : 452)	NC score	0.054818 (rank : 614)
Query Neighborhood Hits	451	Target Neighborhood Hits	376	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

3BP2_HUMAN
θ value	θ > 10 (rank : 453)	NC score	0.110098 (rank : 233)
Query Neighborhood Hits	451	Target Neighborhood Hits	296	Shared Neighborhood Hits	93
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

ACD_HUMAN
θ value	θ > 10 (rank : 454)	NC score	0.055420 (rank : 604)
Query Neighborhood Hits	451	Target Neighborhood Hits	143	Shared Neighborhood Hits	36
SwissProt Accessions	Q96AP0, Q562H5, Q9H8F9	Gene names	ACD, PIP1, PTOP
Domain Architecture	No domain graphic available
Description	Adrenocortical dysplasia protein homolog (POT1 and TIN2-interacting protein).

ACINU_HUMAN
θ value	θ > 10 (rank : 455)	NC score	0.104152 (rank : 259)
Query Neighborhood Hits	451	Target Neighborhood Hits	828	Shared Neighborhood Hits	93
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

ACINU_MOUSE
θ value	θ > 10 (rank : 456)	NC score	0.066707 (rank : 479)
Query Neighborhood Hits	451	Target Neighborhood Hits	712	Shared Neighborhood Hits	76
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

AF9_HUMAN
θ value	θ > 10 (rank : 457)	NC score	0.055498 (rank : 601)
Query Neighborhood Hits	451	Target Neighborhood Hits	202	Shared Neighborhood Hits	25
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

AFF2_HUMAN
θ value	θ > 10 (rank : 458)	NC score	0.119673 (rank : 210)
Query Neighborhood Hits	451	Target Neighborhood Hits	218	Shared Neighborhood Hits	67
SwissProt Accessions	P51816, O43786, O60215, P78407, Q13521, Q14323, Q9UNA5	Gene names	AFF2, FMR2, OX19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation 2 protein) (Protein FMR-2) (FMR2P) (Protein Ox19) (Fragile X E mental retardation syndrome protein).

AFF3_HUMAN
θ value	θ > 10 (rank : 459)	NC score	0.074267 (rank : 413)
Query Neighborhood Hits	451	Target Neighborhood Hits	190	Shared Neighborhood Hits	37
SwissProt Accessions	P51826	Gene names	AFF3, LAF4
Domain Architecture
Description	AF4/FMR2 family member 3 (Protein LAF-4) (Lymphoid nuclear protein related to AF4).

AFF4_MOUSE
θ value	θ > 10 (rank : 460)	NC score	0.122710 (rank : 196)
Query Neighborhood Hits	451	Target Neighborhood Hits	581	Shared Neighborhood Hits	92
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

AKA12_HUMAN
θ value	θ > 10 (rank : 461)	NC score	0.086302 (rank : 342)
Query Neighborhood Hits	451	Target Neighborhood Hits	825	Shared Neighborhood Hits	76
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

AKAP2_MOUSE
θ value	θ > 10 (rank : 462)	NC score	0.054400 (rank : 621)
Query Neighborhood Hits	451	Target Neighborhood Hits	385	Shared Neighborhood Hits	55
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

ALEX_MOUSE
θ value	θ > 10 (rank : 463)	NC score	0.100657 (rank : 272)
Query Neighborhood Hits	451	Target Neighborhood Hits	197	Shared Neighborhood Hits	57
SwissProt Accessions	Q6R0H6, Q8BIR3	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

ALMS1_HUMAN
θ value	θ > 10 (rank : 464)	NC score	0.065126 (rank : 496)
Query Neighborhood Hits	451	Target Neighborhood Hits	356	Shared Neighborhood Hits	62
SwissProt Accessions	Q8TCU4, Q53S05, Q580Q8, Q86VP9, Q9Y4G4	Gene names	ALMS1, KIAA0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1.

ALO17_HUMAN
θ value	θ > 10 (rank : 465)	NC score	0.052955 (rank : 641)
Query Neighborhood Hits	451	Target Neighborhood Hits	317	Shared Neighborhood Hits	45
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

AMELX_MOUSE
θ value	θ > 10 (rank : 466)	NC score	0.053664 (rank : 632)
Query Neighborhood Hits	451	Target Neighborhood Hits	58	Shared Neighborhood Hits	14
SwissProt Accessions	P63277, P45559, P70592, Q61293	Gene names	Amelx, Amel
Domain Architecture	No domain graphic available
Description	Amelogenin, X isoform precursor (Leucine-rich amelogenin peptide) (LRAP).

AMPH_HUMAN
θ value	θ > 10 (rank : 467)	NC score	0.066637 (rank : 480)
Query Neighborhood Hits	451	Target Neighborhood Hits	455	Shared Neighborhood Hits	74
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

ANK2_HUMAN
θ value	θ > 10 (rank : 468)	NC score	0.121378 (rank : 201)
Query Neighborhood Hits	451	Target Neighborhood Hits	1615	Shared Neighborhood Hits	247
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ANR11_HUMAN
θ value	θ > 10 (rank : 469)	NC score	0.068221 (rank : 462)
Query Neighborhood Hits	451	Target Neighborhood Hits	1289	Shared Neighborhood Hits	141
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

ANTR1_MOUSE
θ value	θ > 10 (rank : 470)	NC score	0.058513 (rank : 558)
Query Neighborhood Hits	451	Target Neighborhood Hits	143	Shared Neighborhood Hits	50
SwissProt Accessions	Q9CZ52	Gene names	Antxr1, Atr, Tem8
Domain Architecture
Description	Anthrax toxin receptor 1 precursor (Tumor endothelial marker 8).

APC_HUMAN
θ value	θ > 10 (rank : 471)	NC score	0.065966 (rank : 491)
Query Neighborhood Hits	451	Target Neighborhood Hits	603	Shared Neighborhood Hits	89
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

APXL_HUMAN
θ value	θ > 10 (rank : 472)	NC score	0.077846 (rank : 380)
Query Neighborhood Hits	451	Target Neighborhood Hits	553	Shared Neighborhood Hits	88
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

ARI1B_HUMAN
θ value	θ > 10 (rank : 473)	NC score	0.093821 (rank : 306)
Query Neighborhood Hits	451	Target Neighborhood Hits	567	Shared Neighborhood Hits	120
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

ARI5B_HUMAN
θ value	θ > 10 (rank : 474)	NC score	0.055398 (rank : 605)
Query Neighborhood Hits	451	Target Neighborhood Hits	328	Shared Neighborhood Hits	56
SwissProt Accessions	Q14865, Q7Z3M4, Q8N421, Q9H786	Gene names	ARID5B, DESRT, MRF2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (Mrf1-like) (Modulator recognition factor 2) (MRF-2).

ARMX2_MOUSE
θ value	θ > 10 (rank : 475)	NC score	0.071835 (rank : 435)
Query Neighborhood Hits	451	Target Neighborhood Hits	349	Shared Neighborhood Hits	81
SwissProt Accessions	Q6A058, Q9CXI9	Gene names	Armcx2, Kiaa0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2.

ASPP1_MOUSE
θ value	θ > 10 (rank : 476)	NC score	0.103605 (rank : 261)
Query Neighborhood Hits	451	Target Neighborhood Hits	1244	Shared Neighborhood Hits	169
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ASPP2_HUMAN
θ value	θ > 10 (rank : 477)	NC score	0.055439 (rank : 603)
Query Neighborhood Hits	451	Target Neighborhood Hits	1156	Shared Neighborhood Hits	118
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

ATX1_MOUSE
θ value	θ > 10 (rank : 478)	NC score	0.090706 (rank : 322)
Query Neighborhood Hits	451	Target Neighborhood Hits	264	Shared Neighborhood Hits	83
SwissProt Accessions	P54254	Gene names	Atxn1, Sca1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).

ATX2L_HUMAN
θ value	θ > 10 (rank : 479)	NC score	0.098994 (rank : 279)
Query Neighborhood Hits	451	Target Neighborhood Hits	443	Shared Neighborhood Hits	94
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

ATX2L_MOUSE
θ value	θ > 10 (rank : 480)	NC score	0.092237 (rank : 313)
Query Neighborhood Hits	451	Target Neighborhood Hits	401	Shared Neighborhood Hits	87
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

ATX7_HUMAN
θ value	θ > 10 (rank : 481)	NC score	0.116098 (rank : 216)
Query Neighborhood Hits	451	Target Neighborhood Hits	351	Shared Neighborhood Hits	122
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

ATX7_MOUSE
θ value	θ > 10 (rank : 482)	NC score	0.108277 (rank : 246)
Query Neighborhood Hits	451	Target Neighborhood Hits	328	Shared Neighborhood Hits	111
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

BAG3_HUMAN
θ value	θ > 10 (rank : 483)	NC score	0.122435 (rank : 198)
Query Neighborhood Hits	451	Target Neighborhood Hits	314	Shared Neighborhood Hits	85
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

BASP_HUMAN
θ value	θ > 10 (rank : 484)	NC score	0.120436 (rank : 205)
Query Neighborhood Hits	451	Target Neighborhood Hits	321	Shared Neighborhood Hits	50
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BASP_MOUSE
θ value	θ > 10 (rank : 485)	NC score	0.100044 (rank : 275)
Query Neighborhood Hits	451	Target Neighborhood Hits	260	Shared Neighborhood Hits	35
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BAT3_HUMAN
θ value	θ > 10 (rank : 486)	NC score	0.084159 (rank : 352)
Query Neighborhood Hits	451	Target Neighborhood Hits	490	Shared Neighborhood Hits	107
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

BAT3_MOUSE
θ value	θ > 10 (rank : 487)	NC score	0.093994 (rank : 304)
Query Neighborhood Hits	451	Target Neighborhood Hits	518	Shared Neighborhood Hits	111
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

BAZ1A_HUMAN
θ value	θ > 10 (rank : 488)	NC score	0.052319 (rank : 654)
Query Neighborhood Hits	451	Target Neighborhood Hits	693	Shared Neighborhood Hits	55
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

BAZ2A_HUMAN
θ value	θ > 10 (rank : 489)	NC score	0.083723 (rank : 353)
Query Neighborhood Hits	451	Target Neighborhood Hits	780	Shared Neighborhood Hits	137
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

BAZ2A_MOUSE
θ value	θ > 10 (rank : 490)	NC score	0.102905 (rank : 266)
Query Neighborhood Hits	451	Target Neighborhood Hits	744	Shared Neighborhood Hits	148
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

BCAR1_HUMAN
θ value	θ > 10 (rank : 491)	NC score	0.121318 (rank : 202)
Query Neighborhood Hits	451	Target Neighborhood Hits	554	Shared Neighborhood Hits	138
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

BCAR1_MOUSE
θ value	θ > 10 (rank : 492)	NC score	0.091328 (rank : 320)
Query Neighborhood Hits	451	Target Neighborhood Hits	438	Shared Neighborhood Hits	114
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

BCAS1_MOUSE
θ value	θ > 10 (rank : 493)	NC score	0.056305 (rank : 591)
Query Neighborhood Hits	451	Target Neighborhood Hits	215	Shared Neighborhood Hits	39
SwissProt Accessions	Q80YN3, Q9CVA1	Gene names	Bcas1, Nabc1
Domain Architecture	No domain graphic available
Description	Breast carcinoma amplified sequence 1 homolog (Novel amplified in breast cancer 1 homolog).

BCL9_HUMAN
θ value	θ > 10 (rank : 494)	NC score	0.195791 (rank : 68)
Query Neighborhood Hits	451	Target Neighborhood Hits	1008	Shared Neighborhood Hits	205
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

BCL9_MOUSE
θ value	θ > 10 (rank : 495)	NC score	0.148825 (rank : 135)
Query Neighborhood Hits	451	Target Neighborhood Hits	770	Shared Neighborhood Hits	170
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

BCLF1_HUMAN
θ value	θ > 10 (rank : 496)	NC score	0.055066 (rank : 611)
Query Neighborhood Hits	451	Target Neighborhood Hits	298	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NYF8, Q14673, Q86WU6, Q86WY0	Gene names	BCLAF1, BTF, KIAA0164
Domain Architecture	No domain graphic available
Description	Bcl-2-associated transcription factor 1 (Btf).

BIN1_HUMAN
θ value	θ > 10 (rank : 497)	NC score	0.072967 (rank : 423)
Query Neighborhood Hits	451	Target Neighborhood Hits	335	Shared Neighborhood Hits	71
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

BLNK_HUMAN
θ value	θ > 10 (rank : 498)	NC score	0.066902 (rank : 477)
Query Neighborhood Hits	451	Target Neighborhood Hits	228	Shared Neighborhood Hits	51
SwissProt Accessions	Q8WV28, O75498, O75499	Gene names	BLNK, BASH, SLP65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (SLP-65).

BLNK_MOUSE
θ value	θ > 10 (rank : 499)	NC score	0.108371 (rank : 244)
Query Neighborhood Hits	451	Target Neighborhood Hits	296	Shared Neighborhood Hits	92
SwissProt Accessions	Q9QUN3, O88504	Gene names	Blnk, Bash, Ly57, Slp65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65) (Lymphocyte antigen 57).

BPTF_HUMAN
θ value	θ > 10 (rank : 500)	NC score	0.072739 (rank : 426)
Query Neighborhood Hits	451	Target Neighborhood Hits	786	Shared Neighborhood Hits	88
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

BRD2_HUMAN
θ value	θ > 10 (rank : 501)	NC score	0.062745 (rank : 510)
Query Neighborhood Hits	451	Target Neighborhood Hits	242	Shared Neighborhood Hits	26
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

BRD3_HUMAN
θ value	θ > 10 (rank : 502)	NC score	0.062834 (rank : 507)
Query Neighborhood Hits	451	Target Neighborhood Hits	369	Shared Neighborhood Hits	40
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

BRD3_MOUSE
θ value	θ > 10 (rank : 503)	NC score	0.070676 (rank : 441)
Query Neighborhood Hits	451	Target Neighborhood Hits	402	Shared Neighborhood Hits	41
SwissProt Accessions	Q8K2F0, Q8C665, Q8CAX7, Q9JI25	Gene names	Brd3, Fsrg2
Domain Architecture
Description	Bromodomain-containing protein 3 (Bromodomain-containing FSH-like protein FSRG2).

BRD8_MOUSE
θ value	θ > 10 (rank : 504)	NC score	0.093845 (rank : 305)
Query Neighborhood Hits	451	Target Neighborhood Hits	422	Shared Neighborhood Hits	63
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

BRDT_HUMAN
θ value	θ > 10 (rank : 505)	NC score	0.057280 (rank : 576)
Query Neighborhood Hits	451	Target Neighborhood Hits	280	Shared Neighborhood Hits	19
SwissProt Accessions	Q58F21, O14789, Q6P5T1, Q7Z4A6, Q8IWI6	Gene names	BRDT
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein).

BTBDC_HUMAN
θ value	θ > 10 (rank : 506)	NC score	0.050796 (rank : 678)
Query Neighborhood Hits	451	Target Neighborhood Hits	248	Shared Neighborhood Hits	57
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

CAC1G_HUMAN
θ value	θ > 10 (rank : 507)	NC score	0.069623 (rank : 449)
Query Neighborhood Hits	451	Target Neighborhood Hits	587	Shared Neighborhood Hits	136
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

CASC3_MOUSE
θ value	θ > 10 (rank : 508)	NC score	0.091622 (rank : 315)
Query Neighborhood Hits	451	Target Neighborhood Hits	333	Shared Neighborhood Hits	80
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

CBL_MOUSE
θ value	θ > 10 (rank : 509)	NC score	0.055117 (rank : 609)
Query Neighborhood Hits	451	Target Neighborhood Hits	426	Shared Neighborhood Hits	79
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

CBP_HUMAN
θ value	θ > 10 (rank : 510)	NC score	0.150726 (rank : 131)
Query Neighborhood Hits	451	Target Neighborhood Hits	941	Shared Neighborhood Hits	175
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CBP_MOUSE
θ value	θ > 10 (rank : 511)	NC score	0.165841 (rank : 111)
Query Neighborhood Hits	451	Target Neighborhood Hits	1051	Shared Neighborhood Hits	204
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CCD55_MOUSE
θ value	θ > 10 (rank : 512)	NC score	0.054038 (rank : 626)
Query Neighborhood Hits	451	Target Neighborhood Hits	519	Shared Neighborhood Hits	52
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

CD248_HUMAN
θ value	θ > 10 (rank : 513)	NC score	0.106233 (rank : 251)
Query Neighborhood Hits	451	Target Neighborhood Hits	679	Shared Neighborhood Hits	135
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD248_MOUSE
θ value	θ > 10 (rank : 514)	NC score	0.089060 (rank : 327)
Query Neighborhood Hits	451	Target Neighborhood Hits	578	Shared Neighborhood Hits	128
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CDN1C_HUMAN
θ value	θ > 10 (rank : 515)	NC score	0.072386 (rank : 431)
Query Neighborhood Hits	451	Target Neighborhood Hits	168	Shared Neighborhood Hits	35
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

CECR2_HUMAN
θ value	θ > 10 (rank : 516)	NC score	0.128884 (rank : 182)
Query Neighborhood Hits	451	Target Neighborhood Hits	543	Shared Neighborhood Hits	126
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

CF010_HUMAN
θ value	θ > 10 (rank : 517)	NC score	0.059958 (rank : 539)
Query Neighborhood Hits	451	Target Neighborhood Hits	329	Shared Neighborhood Hits	32
SwissProt Accessions	Q5SRN2, Q5SPI9, Q5SPJ0, Q5SPK9, Q5SPL0, Q5SRN3, Q5TG25, Q5TG26, Q8N4B6	Gene names	C6orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf10.

CG1_HUMAN
θ value	θ > 10 (rank : 518)	NC score	0.097373 (rank : 289)
Query Neighborhood Hits	451	Target Neighborhood Hits	222	Shared Neighborhood Hits	62
SwissProt Accessions	Q13495	Gene names	CXorf6, CG1
Domain Architecture	No domain graphic available
Description	CG1 protein (F18).

CI079_HUMAN
θ value	θ > 10 (rank : 519)	NC score	0.105695 (rank : 252)
Query Neighborhood Hits	451	Target Neighborhood Hits	288	Shared Neighborhood Hits	69
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

CIC_MOUSE
θ value	θ > 10 (rank : 520)	NC score	0.096971 (rank : 292)
Query Neighborhood Hits	451	Target Neighborhood Hits	742	Shared Neighborhood Hits	131
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CJ012_HUMAN
θ value	θ > 10 (rank : 521)	NC score	0.124546 (rank : 192)
Query Neighborhood Hits	451	Target Neighborhood Hits	467	Shared Neighborhood Hits	86
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

CK024_HUMAN
θ value	θ > 10 (rank : 522)	NC score	0.176782 (rank : 87)
Query Neighborhood Hits	451	Target Neighborhood Hits	408	Shared Neighborhood Hits	105
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

CK024_MOUSE
θ value	θ > 10 (rank : 523)	NC score	0.099067 (rank : 278)
Query Neighborhood Hits	451	Target Neighborhood Hits	307	Shared Neighborhood Hits	55
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

CN032_HUMAN
θ value	θ > 10 (rank : 524)	NC score	0.077852 (rank : 379)
Query Neighborhood Hits	451	Target Neighborhood Hits	267	Shared Neighborhood Hits	54
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

CN032_MOUSE
θ value	θ > 10 (rank : 525)	NC score	0.087384 (rank : 337)
Query Neighborhood Hits	451	Target Neighborhood Hits	233	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

CN092_MOUSE
θ value	θ > 10 (rank : 526)	NC score	0.059253 (rank : 549)
Query Neighborhood Hits	451	Target Neighborhood Hits	206	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BU11, Q80UI2, Q99PN9, Q9CS16	Gene names
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

CNOT3_HUMAN
θ value	θ > 10 (rank : 527)	NC score	0.072517 (rank : 429)
Query Neighborhood Hits	451	Target Neighborhood Hits	425	Shared Neighborhood Hits	56
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CNOT3_MOUSE
θ value	θ > 10 (rank : 528)	NC score	0.071507 (rank : 437)
Query Neighborhood Hits	451	Target Neighborhood Hits	504	Shared Neighborhood Hits	65
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CO002_HUMAN
θ value	θ > 10 (rank : 529)	NC score	0.093537 (rank : 307)
Query Neighborhood Hits	451	Target Neighborhood Hits	387	Shared Neighborhood Hits	73
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

CO039_MOUSE
θ value	θ > 10 (rank : 530)	NC score	0.169551 (rank : 102)
Query Neighborhood Hits	451	Target Neighborhood Hits	445	Shared Neighborhood Hits	145
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

CP007_MOUSE
θ value	θ > 10 (rank : 531)	NC score	0.050181 (rank : 683)
Query Neighborhood Hits	451	Target Neighborhood Hits	231	Shared Neighborhood Hits	49
SwissProt Accessions	Q8C190, Q6PFD1	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf7 homolog (5-day ovary-specific transcript 1 protein).

CPSF6_HUMAN
θ value	θ > 10 (rank : 532)	NC score	0.101486 (rank : 270)
Query Neighborhood Hits	451	Target Neighborhood Hits	359	Shared Neighborhood Hits	73
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

CPSF6_MOUSE
θ value	θ > 10 (rank : 533)	NC score	0.103242 (rank : 265)
Query Neighborhood Hits	451	Target Neighborhood Hits	356	Shared Neighborhood Hits	74
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

CRSP2_HUMAN
θ value	θ > 10 (rank : 534)	NC score	0.086879 (rank : 340)
Query Neighborhood Hits	451	Target Neighborhood Hits	380	Shared Neighborhood Hits	88
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

CRSP7_HUMAN
θ value	θ > 10 (rank : 535)	NC score	0.059346 (rank : 546)
Query Neighborhood Hits	451	Target Neighborhood Hits	247	Shared Neighborhood Hits	49
SwissProt Accessions	O95402	Gene names	CRSP7, ARC70
Domain Architecture
Description	CRSP complex subunit 7 (Cofactor required for Sp1 transcriptional activation subunit 7) (Transcriptional coactivator CRSP70) (Activator- recruited cofactor 70 kDa component) (ARC70).

CS007_HUMAN
θ value	θ > 10 (rank : 536)	NC score	0.058115 (rank : 564)
Query Neighborhood Hits	451	Target Neighborhood Hits	401	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

CS007_MOUSE
θ value	θ > 10 (rank : 537)	NC score	0.082734 (rank : 354)
Query Neighborhood Hits	451	Target Neighborhood Hits	464	Shared Neighborhood Hits	85
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

CS016_HUMAN
θ value	θ > 10 (rank : 538)	NC score	0.123662 (rank : 194)
Query Neighborhood Hits	451	Target Neighborhood Hits	310	Shared Neighborhood Hits	72
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

CSF1_HUMAN
θ value	θ > 10 (rank : 539)	NC score	0.107658 (rank : 248)
Query Neighborhood Hits	451	Target Neighborhood Hits	258	Shared Neighborhood Hits	78
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

CSKI2_HUMAN
θ value	θ > 10 (rank : 540)	NC score	0.054677 (rank : 616)
Query Neighborhood Hits	451	Target Neighborhood Hits	747	Shared Neighborhood Hits	79
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CSKI2_MOUSE
θ value	θ > 10 (rank : 541)	NC score	0.054035 (rank : 627)
Query Neighborhood Hits	451	Target Neighborhood Hits	812	Shared Neighborhood Hits	104
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CT151_HUMAN
θ value	θ > 10 (rank : 542)	NC score	0.088227 (rank : 334)
Query Neighborhood Hits	451	Target Neighborhood Hits	382	Shared Neighborhood Hits	63
SwissProt Accessions	Q8NC74, Q8N4Z9, Q9BR75, Q9H0Y9	Gene names	C20orf151
Domain Architecture
Description	Uncharacterized protein C20orf151.

CT174_HUMAN
θ value	θ > 10 (rank : 543)	NC score	0.058252 (rank : 563)
Query Neighborhood Hits	451	Target Neighborhood Hits	181	Shared Neighborhood Hits	49
SwissProt Accessions	Q5JPB2, Q5TDR4, Q8TCP0	Gene names	C20orf174
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf174.

CTDP1_HUMAN
θ value	θ > 10 (rank : 544)	NC score	0.090884 (rank : 321)
Query Neighborhood Hits	451	Target Neighborhood Hits	416	Shared Neighborhood Hits	98
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

DAAM2_HUMAN
θ value	θ > 10 (rank : 545)	NC score	0.093291 (rank : 309)
Query Neighborhood Hits	451	Target Neighborhood Hits	350	Shared Neighborhood Hits	37
SwissProt Accessions	Q86T65, Q5T4U0, Q9NQI5, Q9Y4G0	Gene names	DAAM2, KIAA0381
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 2.

DAAM2_MOUSE
θ value	θ > 10 (rank : 546)	NC score	0.098411 (rank : 283)
Query Neighborhood Hits	451	Target Neighborhood Hits	371	Shared Neighborhood Hits	44
SwissProt Accessions	Q80U19, Q810J5	Gene names	Daam2, Kiaa0381
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 2.

DAB1_HUMAN
θ value	θ > 10 (rank : 547)	NC score	0.058550 (rank : 557)
Query Neighborhood Hits	451	Target Neighborhood Hits	219	Shared Neighborhood Hits	69
SwissProt Accessions	O75553, Q9NYA8	Gene names	DAB1
Domain Architecture
Description	Disabled homolog 1.

DACT1_HUMAN
θ value	θ > 10 (rank : 548)	NC score	0.066977 (rank : 475)
Query Neighborhood Hits	451	Target Neighborhood Hits	228	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NYF0, Q86TY0	Gene names	DACT1, DPR1, HNG3
Domain Architecture	No domain graphic available
Description	Dapper homolog 1 (hDPR1) (Heptacellular carcinoma novel gene 3 protein).

DCC_MOUSE
θ value	θ > 10 (rank : 549)	NC score	0.066208 (rank : 487)
Query Neighborhood Hits	451	Target Neighborhood Hits	896	Shared Neighborhood Hits	146
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

DCP1A_HUMAN
θ value	θ > 10 (rank : 550)	NC score	0.086168 (rank : 344)
Query Neighborhood Hits	451	Target Neighborhood Hits	228	Shared Neighborhood Hits	68
SwissProt Accessions	Q9NPI6	Gene names	DCP1A, SMIF
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (Smad4-interacting transcriptional co-activator).

DIAP3_HUMAN
θ value	θ > 10 (rank : 551)	NC score	0.105345 (rank : 254)
Query Neighborhood Hits	451	Target Neighborhood Hits	209	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NSV4, Q5T2S7, Q5XKF6, Q6MZF0, Q6NUP0, Q86VS4, Q8NAV4	Gene names	DIAPH3, DIAP3
Domain Architecture	No domain graphic available
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3).

DIAP3_MOUSE
θ value	θ > 10 (rank : 552)	NC score	0.114557 (rank : 218)
Query Neighborhood Hits	451	Target Neighborhood Hits	221	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Z207	Gene names	Diaph3, Diap3
Domain Architecture
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3) (mDIA2) (p134mDIA2).

DMP1_HUMAN
θ value	θ > 10 (rank : 553)	NC score	0.050884 (rank : 676)
Query Neighborhood Hits	451	Target Neighborhood Hits	491	Shared Neighborhood Hits	33
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

DMP1_MOUSE
θ value	θ > 10 (rank : 554)	NC score	0.052617 (rank : 647)
Query Neighborhood Hits	451	Target Neighborhood Hits	498	Shared Neighborhood Hits	32
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

DNL1_HUMAN
θ value	θ > 10 (rank : 555)	NC score	0.054497 (rank : 619)
Query Neighborhood Hits	451	Target Neighborhood Hits	216	Shared Neighborhood Hits	41
SwissProt Accessions	P18858	Gene names	LIG1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

DNMT1_HUMAN
θ value	θ > 10 (rank : 556)	NC score	0.075596 (rank : 401)
Query Neighborhood Hits	451	Target Neighborhood Hits	401	Shared Neighborhood Hits	55
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

DOK2_MOUSE
θ value	θ > 10 (rank : 557)	NC score	0.069066 (rank : 457)
Query Neighborhood Hits	451	Target Neighborhood Hits	244	Shared Neighborhood Hits	81
SwissProt Accessions	O70469, O70272, Q99KL1	Gene names	Dok2, Frip
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)) (Dok- related protein) (Dok-R) (IL-four receptor-interacting protein) (FRIP).

DOT1L_HUMAN
θ value	θ > 10 (rank : 558)	NC score	0.077433 (rank : 389)
Query Neighborhood Hits	451	Target Neighborhood Hits	660	Shared Neighborhood Hits	91
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

DSPP_HUMAN
θ value	θ > 10 (rank : 559)	NC score	0.057185 (rank : 578)
Query Neighborhood Hits	451	Target Neighborhood Hits	645	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

DSPP_MOUSE
θ value	θ > 10 (rank : 560)	NC score	0.051814 (rank : 661)
Query Neighborhood Hits	451	Target Neighborhood Hits	491	Shared Neighborhood Hits	38
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

ECM1_HUMAN
θ value	θ > 10 (rank : 561)	NC score	0.063107 (rank : 505)
Query Neighborhood Hits	451	Target Neighborhood Hits	182	Shared Neighborhood Hits	59
SwissProt Accessions	Q16610	Gene names	ECM1
Domain Architecture
Description	Extracellular matrix protein 1 precursor (Secretory component p85).

EFS_HUMAN
θ value	θ > 10 (rank : 562)	NC score	0.068058 (rank : 466)
Query Neighborhood Hits	451	Target Neighborhood Hits	348	Shared Neighborhood Hits	75
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

EFS_MOUSE
θ value	θ > 10 (rank : 563)	NC score	0.066022 (rank : 490)
Query Neighborhood Hits	451	Target Neighborhood Hits	389	Shared Neighborhood Hits	86
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

ELOA1_HUMAN
θ value	θ > 10 (rank : 564)	NC score	0.076055 (rank : 398)
Query Neighborhood Hits	451	Target Neighborhood Hits	388	Shared Neighborhood Hits	62
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

EMSY_HUMAN
θ value	θ > 10 (rank : 565)	NC score	0.062256 (rank : 513)
Query Neighborhood Hits	451	Target Neighborhood Hits	296	Shared Neighborhood Hits	50
SwissProt Accessions	Q7Z589, Q4G109, Q8NBU6, Q8TE50, Q9H8I9, Q9NRH0	Gene names	EMSY, C11orf30
Domain Architecture
Description	Protein EMSY.

EMSY_MOUSE
θ value	θ > 10 (rank : 566)	NC score	0.063617 (rank : 501)
Query Neighborhood Hits	451	Target Neighborhood Hits	294	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BMB0, Q5FWK5, Q80XU1, Q8VDW9	Gene names	Emsy
Domain Architecture
Description	Protein EMSY.

ENAH_HUMAN
θ value	θ > 10 (rank : 567)	NC score	0.058449 (rank : 559)
Query Neighborhood Hits	451	Target Neighborhood Hits	784	Shared Neighborhood Hits	85
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

ENAM_HUMAN
θ value	θ > 10 (rank : 568)	NC score	0.055105 (rank : 610)
Query Neighborhood Hits	451	Target Neighborhood Hits	227	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NRM1, Q9H3D1	Gene names	ENAM
Domain Architecture
Description	Enamelin precursor.

ENAM_MOUSE
θ value	θ > 10 (rank : 569)	NC score	0.090697 (rank : 323)
Query Neighborhood Hits	451	Target Neighborhood Hits	229	Shared Neighborhood Hits	64
SwissProt Accessions	O55196	Gene names	Enam
Domain Architecture	No domain graphic available
Description	Enamelin precursor.

EPN3_MOUSE
θ value	θ > 10 (rank : 570)	NC score	0.071815 (rank : 436)
Query Neighborhood Hits	451	Target Neighborhood Hits	312	Shared Neighborhood Hits	79
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

ESCO1_HUMAN
θ value	θ > 10 (rank : 571)	NC score	0.057574 (rank : 569)
Query Neighborhood Hits	451	Target Neighborhood Hits	361	Shared Neighborhood Hits	38
SwissProt Accessions	Q5FWF5, Q69YG4, Q69YS3, Q6IMD7, Q8N3Z5, Q8NBG2, Q96PX7	Gene names	ESCO1, EFO1, KIAA1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1) (Establishment factor- like protein 1) (EFO1p) (hEFO1) (CTF7 homolog 1).

ETV3_HUMAN
θ value	θ > 10 (rank : 572)	NC score	0.059605 (rank : 542)
Query Neighborhood Hits	451	Target Neighborhood Hits	312	Shared Neighborhood Hits	76
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

EVL_HUMAN
θ value	θ > 10 (rank : 573)	NC score	0.068720 (rank : 459)
Query Neighborhood Hits	451	Target Neighborhood Hits	260	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UI08, O95884, Q7Z522, Q8TBV1, Q9UF25, Q9UIC2	Gene names	EVL, RNB6
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

EVL_MOUSE
θ value	θ > 10 (rank : 574)	NC score	0.060015 (rank : 538)
Query Neighborhood Hits	451	Target Neighborhood Hits	203	Shared Neighborhood Hits	55
SwissProt Accessions	P70429, Q9ERU8	Gene names	Evl
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

FHOD1_HUMAN
θ value	θ > 10 (rank : 575)	NC score	0.127344 (rank : 185)
Query Neighborhood Hits	451	Target Neighborhood Hits	184	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Y613, Q59F76, Q6Y1F2, Q76MS8, Q8N521	Gene names	FHOD1, FHOS
Domain Architecture
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

FXL19_MOUSE
θ value	θ > 10 (rank : 576)	NC score	0.053997 (rank : 629)
Query Neighborhood Hits	451	Target Neighborhood Hits	217	Shared Neighborhood Hits	66
SwissProt Accessions	Q6PB97, Q7TSH0, Q8BIB4	Gene names	Fbxl19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

FYB_HUMAN
θ value	θ > 10 (rank : 577)	NC score	0.119903 (rank : 209)
Query Neighborhood Hits	451	Target Neighborhood Hits	379	Shared Neighborhood Hits	101
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

G3BP2_HUMAN
θ value	θ > 10 (rank : 578)	NC score	0.051342 (rank : 671)
Query Neighborhood Hits	451	Target Neighborhood Hits	260	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UN86, O60606, O75149, Q9UPA1	Gene names	G3BP2, KIAA0660
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 2 (GAP SH3-domain- binding protein 2) (G3BP-2).

G3BP2_MOUSE
θ value	θ > 10 (rank : 579)	NC score	0.052669 (rank : 646)
Query Neighborhood Hits	451	Target Neighborhood Hits	258	Shared Neighborhood Hits	33
SwissProt Accessions	P97379, Q9R1B8	Gene names	G3bp2
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 2 (GAP SH3-domain- binding protein 2) (G3BP-2).

GA2L3_HUMAN
θ value	θ > 10 (rank : 580)	NC score	0.074134 (rank : 416)
Query Neighborhood Hits	451	Target Neighborhood Hits	189	Shared Neighborhood Hits	47
SwissProt Accessions	Q86XJ1	Gene names	GAS2L3
Domain Architecture	No domain graphic available
Description	GAS2-like protein 3 (Growth arrest-specific 2-like 3).

GAB1_HUMAN
θ value	θ > 10 (rank : 581)	NC score	0.077533 (rank : 387)
Query Neighborhood Hits	451	Target Neighborhood Hits	279	Shared Neighborhood Hits	99
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

GAB1_MOUSE
θ value	θ > 10 (rank : 582)	NC score	0.073039 (rank : 422)
Query Neighborhood Hits	451	Target Neighborhood Hits	233	Shared Neighborhood Hits	84
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

GAK13_HUMAN
θ value	θ > 10 (rank : 583)	NC score	0.060577 (rank : 529)
Query Neighborhood Hits	451	Target Neighborhood Hits	21	Shared Neighborhood Hits	9
SwissProt Accessions	P62686	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1p13.3 provirus ancestral Gag polyprotein (Gag polyprotein).

GAK14_HUMAN
θ value	θ > 10 (rank : 584)	NC score	0.063066 (rank : 506)
Query Neighborhood Hits	451	Target Neighborhood Hits	18	Shared Neighborhood Hits	9
SwissProt Accessions	P62687	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_16p3.3 provirus ancestral Gag polyprotein (Gag polyprotein).

GAK15_HUMAN
θ value	θ > 10 (rank : 585)	NC score	0.067854 (rank : 467)
Query Neighborhood Hits	451	Target Neighborhood Hits	19	Shared Neighborhood Hits	9
SwissProt Accessions	P62688	Gene names	ERVK4
Domain Architecture	No domain graphic available
Description	HERV-K_3q21.2 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(I) Gag protein).

GAK17_HUMAN
θ value	θ > 10 (rank : 586)	NC score	0.068217 (rank : 463)
Query Neighborhood Hits	451	Target Neighborhood Hits	21	Shared Neighborhood Hits	9
SwissProt Accessions	P62689	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_11q22.1 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein].

GAK18_HUMAN
θ value	θ > 10 (rank : 587)	NC score	0.088502 (rank : 333)
Query Neighborhood Hits	451	Target Neighborhood Hits	116	Shared Neighborhood Hits	46
SwissProt Accessions	P62690	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.23 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK19_HUMAN
θ value	θ > 10 (rank : 588)	NC score	0.065536 (rank : 494)
Query Neighborhood Hits	451	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	P62691	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_4p16.1 provirus ancestral Gag polyprotein (Gag polyprotein).

GAK7_HUMAN
θ value	θ > 10 (rank : 589)	NC score	0.086352 (rank : 341)
Query Neighborhood Hits	451	Target Neighborhood Hits	90	Shared Neighborhood Hits	37
SwissProt Accessions	Q96PI4, Q9QC08	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q23.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K18 Gag protein) (HERV-K110 Gag protein) (HERV-K(C1a) Gag protein) [Contains: Matrix protein].

GAK8_HUMAN
θ value	θ > 10 (rank : 590)	NC score	0.090082 (rank : 325)
Query Neighborhood Hits	451	Target Neighborhood Hits	145	Shared Neighborhood Hits	54
SwissProt Accessions	Q9HDB9	Gene names	ERVK5
Domain Architecture	No domain graphic available
Description	HERV-K_3q12.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(II) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK9_HUMAN
θ value	θ > 10 (rank : 591)	NC score	0.068112 (rank : 465)
Query Neighborhood Hits	451	Target Neighborhood Hits	22	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UKH8	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q13.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K104 Gag protein) [Contains: Matrix protein].

GNAS1_MOUSE
θ value	θ > 10 (rank : 592)	NC score	0.094595 (rank : 303)
Query Neighborhood Hits	451	Target Neighborhood Hits	651	Shared Neighborhood Hits	139
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

GNAS3_HUMAN
θ value	θ > 10 (rank : 593)	NC score	0.055842 (rank : 597)
Query Neighborhood Hits	451	Target Neighborhood Hits	71	Shared Neighborhood Hits	18
SwissProt Accessions	O95467, O95417	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Neuroendocrine secretory protein 55 (NESP55) [Contains: LHAL tetrapeptide; GPIPIRRH peptide].

GON4L_MOUSE
θ value	θ > 10 (rank : 594)	NC score	0.084574 (rank : 349)
Query Neighborhood Hits	451	Target Neighborhood Hits	455	Shared Neighborhood Hits	86
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

GP112_HUMAN
θ value	θ > 10 (rank : 595)	NC score	0.060745 (rank : 527)
Query Neighborhood Hits	451	Target Neighborhood Hits	441	Shared Neighborhood Hits	48
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

GPS2_HUMAN
θ value	θ > 10 (rank : 596)	NC score	0.051303 (rank : 672)
Query Neighborhood Hits	451	Target Neighborhood Hits	459	Shared Neighborhood Hits	53
SwissProt Accessions	Q13227	Gene names	GPS2
Domain Architecture	No domain graphic available
Description	G protein pathway suppressor 2 (Protein GPS2).

GPTC8_HUMAN
θ value	θ > 10 (rank : 597)	NC score	0.080991 (rank : 365)
Query Neighborhood Hits	451	Target Neighborhood Hits	366	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

GRIN1_HUMAN
θ value	θ > 10 (rank : 598)	NC score	0.120413 (rank : 206)
Query Neighborhood Hits	451	Target Neighborhood Hits	681	Shared Neighborhood Hits	101
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

GRIN1_MOUSE
θ value	θ > 10 (rank : 599)	NC score	0.110417 (rank : 230)
Query Neighborhood Hits	451	Target Neighborhood Hits	337	Shared Neighborhood Hits	87
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

GTSE1_HUMAN
θ value	θ > 10 (rank : 600)	NC score	0.108129 (rank : 247)
Query Neighborhood Hits	451	Target Neighborhood Hits	193	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NYZ3, Q53GX5, Q5R3I6, Q6DHX4, Q9BRE0, Q9UGZ9, Q9Y557	Gene names	GTSE1
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (B99 homolog).

GTSE1_MOUSE
θ value	θ > 10 (rank : 601)	NC score	0.075677 (rank : 400)
Query Neighborhood Hits	451	Target Neighborhood Hits	245	Shared Neighborhood Hits	59
SwissProt Accessions	Q8R080, O89015, Q9CSG9	Gene names	Gtse1, B99
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (Gtse-1) (B99 protein).

HCLS1_HUMAN
θ value	θ > 10 (rank : 602)	NC score	0.056278 (rank : 592)
Query Neighborhood Hits	451	Target Neighborhood Hits	358	Shared Neighborhood Hits	83
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

HSF1_MOUSE
θ value	θ > 10 (rank : 603)	NC score	0.067703 (rank : 469)
Query Neighborhood Hits	451	Target Neighborhood Hits	267	Shared Neighborhood Hits	72
SwissProt Accessions	P38532, O70462	Gene names	Hsf1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

IASPP_MOUSE
θ value	θ > 10 (rank : 604)	NC score	0.104799 (rank : 255)
Query Neighborhood Hits	451	Target Neighborhood Hits	1024	Shared Neighborhood Hits	167
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

ICAL_HUMAN
θ value	θ > 10 (rank : 605)	NC score	0.070072 (rank : 447)
Query Neighborhood Hits	451	Target Neighborhood Hits	275	Shared Neighborhood Hits	54
SwissProt Accessions	P20810, O95360, Q96D08, Q9H1Z5	Gene names	CAST
Domain Architecture
Description	Calpastatin (Calpain inhibitor) (Sperm BS-17 component).

ICAL_MOUSE
θ value	θ > 10 (rank : 606)	NC score	0.054384 (rank : 622)
Query Neighborhood Hits	451	Target Neighborhood Hits	178	Shared Neighborhood Hits	24
SwissProt Accessions	P51125, Q9EQV4, Q9EQV5, Q9QXQ3, Q9QXQ4, Q9R0N1	Gene names	Cast
Domain Architecture
Description	Calpastatin (Calpain inhibitor).

IF4B_HUMAN
θ value	θ > 10 (rank : 607)	NC score	0.077332 (rank : 391)
Query Neighborhood Hits	451	Target Neighborhood Hits	417	Shared Neighborhood Hits	86
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

IF4B_MOUSE
θ value	θ > 10 (rank : 608)	NC score	0.081782 (rank : 358)
Query Neighborhood Hits	451	Target Neighborhood Hits	368	Shared Neighborhood Hits	93
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

IF4G1_MOUSE
θ value	θ > 10 (rank : 609)	NC score	0.124376 (rank : 193)
Query Neighborhood Hits	451	Target Neighborhood Hits	534	Shared Neighborhood Hits	141
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

IF4G3_MOUSE
θ value	θ > 10 (rank : 610)	NC score	0.056632 (rank : 586)
Query Neighborhood Hits	451	Target Neighborhood Hits	279	Shared Neighborhood Hits	38
SwissProt Accessions	Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0	Gene names	Eif4g3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

IL3B2_MOUSE
θ value	θ > 10 (rank : 611)	NC score	0.068171 (rank : 464)
Query Neighborhood Hits	451	Target Neighborhood Hits	372	Shared Neighborhood Hits	97
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

IL3RB_MOUSE
θ value	θ > 10 (rank : 612)	NC score	0.067243 (rank : 473)
Query Neighborhood Hits	451	Target Neighborhood Hits	355	Shared Neighborhood Hits	95
SwissProt Accessions	P26955	Gene names	Csf2rb, Aic2b, Csf2rb1, Il3rb1
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen).

INP5E_HUMAN
θ value	θ > 10 (rank : 613)	NC score	0.078514 (rank : 376)
Query Neighborhood Hits	451	Target Neighborhood Hits	201	Shared Neighborhood Hits	68
SwissProt Accessions	Q9NRR6, Q15734	Gene names	INPP5E
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

IQEC3_MOUSE
θ value	θ > 10 (rank : 614)	NC score	0.051395 (rank : 669)
Query Neighborhood Hits	451	Target Neighborhood Hits	274	Shared Neighborhood Hits	53
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

IRS2_MOUSE
θ value	θ > 10 (rank : 615)	NC score	0.066466 (rank : 484)
Query Neighborhood Hits	451	Target Neighborhood Hits	248	Shared Neighborhood Hits	46
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

JADE2_MOUSE
θ value	θ > 10 (rank : 616)	NC score	0.103571 (rank : 262)
Query Neighborhood Hits	451	Target Neighborhood Hits	560	Shared Neighborhood Hits	148
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

JIP1_HUMAN
θ value	θ > 10 (rank : 617)	NC score	0.057049 (rank : 579)
Query Neighborhood Hits	451	Target Neighborhood Hits	271	Shared Neighborhood Hits	68
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

JIP1_MOUSE
θ value	θ > 10 (rank : 618)	NC score	0.067162 (rank : 474)
Query Neighborhood Hits	451	Target Neighborhood Hits	259	Shared Neighborhood Hits	67
SwissProt Accessions	Q9WVI9, O35145, Q925J8, Q9R1H9, Q9R1Z1, Q9WVI7, Q9WVI8	Gene names	Mapk8ip1, Ib1, Jip1, Mapk8ip, Prkm8ip
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain-1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

JIP3_HUMAN
θ value	θ > 10 (rank : 619)	NC score	0.057254 (rank : 577)
Query Neighborhood Hits	451	Target Neighborhood Hits	1039	Shared Neighborhood Hits	129
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

JPH2_HUMAN
θ value	θ > 10 (rank : 620)	NC score	0.098821 (rank : 281)
Query Neighborhood Hits	451	Target Neighborhood Hits	639	Shared Neighborhood Hits	159
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

K0310_HUMAN
θ value	θ > 10 (rank : 621)	NC score	0.111525 (rank : 227)
Query Neighborhood Hits	451	Target Neighborhood Hits	420	Shared Neighborhood Hits	104
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

K1210_HUMAN
θ value	θ > 10 (rank : 622)	NC score	0.085822 (rank : 345)
Query Neighborhood Hits	451	Target Neighborhood Hits	219	Shared Neighborhood Hits	54
SwissProt Accessions	Q9ULL0, Q5JPN4	Gene names	KIAA1210
Domain Architecture	No domain graphic available
Description	Protein KIAA1210.

K1683_HUMAN
θ value	θ > 10 (rank : 623)	NC score	0.144816 (rank : 151)
Query Neighborhood Hits	451	Target Neighborhood Hits	240	Shared Neighborhood Hits	71
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

KI67_HUMAN
θ value	θ > 10 (rank : 624)	NC score	0.139141 (rank : 160)
Query Neighborhood Hits	451	Target Neighborhood Hits	581	Shared Neighborhood Hits	92
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

LAD1_HUMAN
θ value	θ > 10 (rank : 625)	NC score	0.182397 (rank : 84)
Query Neighborhood Hits	451	Target Neighborhood Hits	441	Shared Neighborhood Hits	102
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

LARP4_MOUSE
θ value	θ > 10 (rank : 626)	NC score	0.102688 (rank : 267)
Query Neighborhood Hits	451	Target Neighborhood Hits	260	Shared Neighborhood Hits	84
SwissProt Accessions	Q8BWW4, Q3UR69	Gene names	Larp4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

LEO1_HUMAN
θ value	θ > 10 (rank : 627)	NC score	0.061474 (rank : 519)
Query Neighborhood Hits	451	Target Neighborhood Hits	958	Shared Neighborhood Hits	69
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

LEO1_MOUSE
θ value	θ > 10 (rank : 628)	NC score	0.053245 (rank : 637)
Query Neighborhood Hits	451	Target Neighborhood Hits	946	Shared Neighborhood Hits	65
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

LEUK_HUMAN
θ value	θ > 10 (rank : 629)	NC score	0.088695 (rank : 330)
Query Neighborhood Hits	451	Target Neighborhood Hits	213	Shared Neighborhood Hits	39
SwissProt Accessions	P16150	Gene names	SPN, CD43
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Galactoglycoprotein) (GALGP) (CD43 antigen).

LEUK_MOUSE
θ value	θ > 10 (rank : 630)	NC score	0.059611 (rank : 541)
Query Neighborhood Hits	451	Target Neighborhood Hits	147	Shared Neighborhood Hits	27
SwissProt Accessions	P15702	Gene names	Spn
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Ly- 48) (B cell differentiation antigen LP-3) (CD43 antigen).

LPP_HUMAN
θ value	θ > 10 (rank : 631)	NC score	0.153397 (rank : 128)
Query Neighborhood Hits	451	Target Neighborhood Hits	775	Shared Neighborhood Hits	188
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

MAGD4_HUMAN
θ value	θ > 10 (rank : 632)	NC score	0.053999 (rank : 628)
Query Neighborhood Hits	451	Target Neighborhood Hits	338	Shared Neighborhood Hits	82
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

MAP2_HUMAN
θ value	θ > 10 (rank : 633)	NC score	0.056420 (rank : 590)
Query Neighborhood Hits	451	Target Neighborhood Hits	348	Shared Neighborhood Hits	58
SwissProt Accessions	P11137, Q99975, Q99976	Gene names	MAP2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2) (MAP-2).

MAP2_MOUSE
θ value	θ > 10 (rank : 634)	NC score	0.054847 (rank : 612)
Query Neighborhood Hits	451	Target Neighborhood Hits	342	Shared Neighborhood Hits	61
SwissProt Accessions	P20357	Gene names	Map2, Mtap2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2).

MAP4_MOUSE
θ value	θ > 10 (rank : 635)	NC score	0.131991 (rank : 174)
Query Neighborhood Hits	451	Target Neighborhood Hits	409	Shared Neighborhood Hits	82
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MARCS_HUMAN
θ value	θ > 10 (rank : 636)	NC score	0.077666 (rank : 385)
Query Neighborhood Hits	451	Target Neighborhood Hits	204	Shared Neighborhood Hits	38
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

MARCS_MOUSE
θ value	θ > 10 (rank : 637)	NC score	0.072166 (rank : 433)
Query Neighborhood Hits	451	Target Neighborhood Hits	227	Shared Neighborhood Hits	33
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

MAVS_HUMAN
θ value	θ > 10 (rank : 638)	NC score	0.076340 (rank : 396)
Query Neighborhood Hits	451	Target Neighborhood Hits	271	Shared Neighborhood Hits	62
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

MAVS_MOUSE
θ value	θ > 10 (rank : 639)	NC score	0.054469 (rank : 620)
Query Neighborhood Hits	451	Target Neighborhood Hits	170	Shared Neighborhood Hits	48
SwissProt Accessions	Q8VCF0	Gene names	Mavs, Ips1, Visa
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif).

MBB1A_HUMAN
θ value	θ > 10 (rank : 640)	NC score	0.145522 (rank : 148)
Query Neighborhood Hits	451	Target Neighborhood Hits	665	Shared Neighborhood Hits	131
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

MBD5_HUMAN
θ value	θ > 10 (rank : 641)	NC score	0.056822 (rank : 583)
Query Neighborhood Hits	451	Target Neighborhood Hits	176	Shared Neighborhood Hits	43
SwissProt Accessions	Q9P267, Q9NUV6	Gene names	MBD5, KIAA1461
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 5 (Methyl-CpG-binding protein MBD5).

MDC1_MOUSE
θ value	θ > 10 (rank : 642)	NC score	0.272062 (rank : 13)
Query Neighborhood Hits	451	Target Neighborhood Hits	998	Shared Neighborhood Hits	217
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MDN1_HUMAN
θ value	θ > 10 (rank : 643)	NC score	0.052409 (rank : 653)
Query Neighborhood Hits	451	Target Neighborhood Hits	662	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

MECP2_HUMAN
θ value	θ > 10 (rank : 644)	NC score	0.052544 (rank : 648)
Query Neighborhood Hits	451	Target Neighborhood Hits	92	Shared Neighborhood Hits	26
SwissProt Accessions	P51608, O15233	Gene names	MECP2
Domain Architecture
Description	Methyl-CpG-binding protein 2 (MeCP-2 protein) (MeCP2).

MEF2B_MOUSE
θ value	θ > 10 (rank : 645)	NC score	0.061482 (rank : 518)
Query Neighborhood Hits	451	Target Neighborhood Hits	218	Shared Neighborhood Hits	52
SwissProt Accessions	O55087, O55088, O55089, O55090, O55231, Q61843	Gene names	Mef2b
Domain Architecture
Description	Myocyte-specific enhancer factor 2B.

MEGF9_MOUSE
θ value	θ > 10 (rank : 646)	NC score	0.079366 (rank : 372)
Query Neighborhood Hits	451	Target Neighborhood Hits	896	Shared Neighborhood Hits	141
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MILK1_HUMAN
θ value	θ > 10 (rank : 647)	NC score	0.069342 (rank : 455)
Query Neighborhood Hits	451	Target Neighborhood Hits	427	Shared Neighborhood Hits	81
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MILK1_MOUSE
θ value	θ > 10 (rank : 648)	NC score	0.120406 (rank : 207)
Query Neighborhood Hits	451	Target Neighborhood Hits	788	Shared Neighborhood Hits	177
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MILK2_HUMAN
θ value	θ > 10 (rank : 649)	NC score	0.052914 (rank : 642)
Query Neighborhood Hits	451	Target Neighborhood Hits	457	Shared Neighborhood Hits	65
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

MINT_HUMAN
θ value	θ > 10 (rank : 650)	NC score	0.129540 (rank : 178)
Query Neighborhood Hits	451	Target Neighborhood Hits	1291	Shared Neighborhood Hits	184
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MISS_MOUSE
θ value	θ > 10 (rank : 651)	NC score	0.186664 (rank : 78)
Query Neighborhood Hits	451	Target Neighborhood Hits	444	Shared Neighborhood Hits	138
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

MLL3_MOUSE
θ value	θ > 10 (rank : 652)	NC score	0.179768 (rank : 85)
Query Neighborhood Hits	451	Target Neighborhood Hits	1399	Shared Neighborhood Hits	225
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MNT_HUMAN
θ value	θ > 10 (rank : 653)	NC score	0.136595 (rank : 164)
Query Neighborhood Hits	451	Target Neighborhood Hits	496	Shared Neighborhood Hits	123
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MTSS1_HUMAN
θ value	θ > 10 (rank : 654)	NC score	0.104290 (rank : 258)
Query Neighborhood Hits	451	Target Neighborhood Hits	504	Shared Neighborhood Hits	102
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

MTSS1_MOUSE
θ value	θ > 10 (rank : 655)	NC score	0.128943 (rank : 181)
Query Neighborhood Hits	451	Target Neighborhood Hits	592	Shared Neighborhood Hits	140
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

MUC13_MOUSE
θ value	θ > 10 (rank : 656)	NC score	0.052826 (rank : 645)
Query Neighborhood Hits	451	Target Neighborhood Hits	447	Shared Neighborhood Hits	48
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

MUC1_HUMAN
θ value	θ > 10 (rank : 657)	NC score	0.256642 (rank : 19)
Query Neighborhood Hits	451	Target Neighborhood Hits	975	Shared Neighborhood Hits	197
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

MUC1_MOUSE
θ value	θ > 10 (rank : 658)	NC score	0.096474 (rank : 294)
Query Neighborhood Hits	451	Target Neighborhood Hits	388	Shared Neighborhood Hits	58
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

MUCDL_HUMAN
θ value	θ > 10 (rank : 659)	NC score	0.145446 (rank : 150)
Query Neighborhood Hits	451	Target Neighborhood Hits	777	Shared Neighborhood Hits	149
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

MUCDL_MOUSE
θ value	θ > 10 (rank : 660)	NC score	0.054844 (rank : 613)
Query Neighborhood Hits	451	Target Neighborhood Hits	461	Shared Neighborhood Hits	66
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

MUCEN_MOUSE
θ value	θ > 10 (rank : 661)	NC score	0.060223 (rank : 534)
Query Neighborhood Hits	451	Target Neighborhood Hits	65	Shared Neighborhood Hits	15
SwissProt Accessions	Q9R0H2, Q78KL2, Q9DCN9, Q9ULC1, Q9Z2I1	Gene names	Emcn, Muc14
Domain Architecture	No domain graphic available
Description	Endomucin precursor (Endomucin-1/2).

MYCB2_HUMAN
θ value	θ > 10 (rank : 662)	NC score	0.053655 (rank : 633)
Query Neighborhood Hits	451	Target Neighborhood Hits	390	Shared Neighborhood Hits	51
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

MYO15_MOUSE
θ value	θ > 10 (rank : 663)	NC score	0.057333 (rank : 573)
Query Neighborhood Hits	451	Target Neighborhood Hits	467	Shared Neighborhood Hits	118
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

MYST3_HUMAN
θ value	θ > 10 (rank : 664)	NC score	0.070749 (rank : 439)
Query Neighborhood Hits	451	Target Neighborhood Hits	772	Shared Neighborhood Hits	93
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

NASP_HUMAN
θ value	θ > 10 (rank : 665)	NC score	0.065256 (rank : 495)
Query Neighborhood Hits	451	Target Neighborhood Hits	709	Shared Neighborhood Hits	57
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

NCOA6_HUMAN
θ value	θ > 10 (rank : 666)	NC score	0.221099 (rank : 44)
Query Neighborhood Hits	451	Target Neighborhood Hits	1202	Shared Neighborhood Hits	237
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NCOR1_HUMAN
θ value	θ > 10 (rank : 667)	NC score	0.091400 (rank : 319)
Query Neighborhood Hits	451	Target Neighborhood Hits	577	Shared Neighborhood Hits	85
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

NCOR1_MOUSE
θ value	θ > 10 (rank : 668)	NC score	0.081245 (rank : 361)
Query Neighborhood Hits	451	Target Neighborhood Hits	521	Shared Neighborhood Hits	78
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

NELFA_HUMAN
θ value	θ > 10 (rank : 669)	NC score	0.056036 (rank : 594)
Query Neighborhood Hits	451	Target Neighborhood Hits	161	Shared Neighborhood Hits	45
SwissProt Accessions	Q9H3P2, O95392	Gene names	WHSC2, NELFA
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 protein).

NELFA_MOUSE
θ value	θ > 10 (rank : 670)	NC score	0.064779 (rank : 497)
Query Neighborhood Hits	451	Target Neighborhood Hits	195	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BG30, Q8BVE4, Q8VEI7, Q9CSJ9, Q9Z1V9	Gene names	Whsc2, Nelfa, Whsc2h
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 homolog) (mWHSC2).

NEUM_HUMAN
θ value	θ > 10 (rank : 671)	NC score	0.058312 (rank : 562)
Query Neighborhood Hits	451	Target Neighborhood Hits	132	Shared Neighborhood Hits	27
SwissProt Accessions	P17677	Gene names	GAP43
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (PP46) (Neural phosphoprotein B-50).

NEUM_MOUSE
θ value	θ > 10 (rank : 672)	NC score	0.058049 (rank : 565)
Query Neighborhood Hits	451	Target Neighborhood Hits	149	Shared Neighborhood Hits	24
SwissProt Accessions	P06837	Gene names	Gap43, Basp2
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (Calmodulin-binding protein P-57).

NFAC1_HUMAN
θ value	θ > 10 (rank : 673)	NC score	0.057014 (rank : 581)
Query Neighborhood Hits	451	Target Neighborhood Hits	312	Shared Neighborhood Hits	85
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

NFRKB_HUMAN
θ value	θ > 10 (rank : 674)	NC score	0.058951 (rank : 552)
Query Neighborhood Hits	451	Target Neighborhood Hits	211	Shared Neighborhood Hits	39
SwissProt Accessions	Q6P4R8, Q12869, Q15312, Q9H048	Gene names	NFRKB
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

NFRKB_MOUSE
θ value	θ > 10 (rank : 675)	NC score	0.087925 (rank : 335)
Query Neighborhood Hits	451	Target Neighborhood Hits	393	Shared Neighborhood Hits	97
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

NHS_HUMAN
θ value	θ > 10 (rank : 676)	NC score	0.058643 (rank : 554)
Query Neighborhood Hits	451	Target Neighborhood Hits	198	Shared Neighborhood Hits	47
SwissProt Accessions	Q6T4R5, Q5J7Q0, Q5J7Q1, Q68DR5	Gene names	NHS
Domain Architecture	No domain graphic available
Description	Nance-Horan syndrome protein (Congenital cataracts and dental anomalies protein).

NOL3_MOUSE
θ value	θ > 10 (rank : 677)	NC score	0.061135 (rank : 524)
Query Neighborhood Hits	451	Target Neighborhood Hits	97	Shared Neighborhood Hits	24
SwissProt Accessions	Q9D1X0	Gene names	Nol3
Domain Architecture
Description	Nucleolar protein 3.

NPAS4_HUMAN
θ value	θ > 10 (rank : 678)	NC score	0.067710 (rank : 468)
Query Neighborhood Hits	451	Target Neighborhood Hits	214	Shared Neighborhood Hits	56
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

NPAS4_MOUSE
θ value	θ > 10 (rank : 679)	NC score	0.073354 (rank : 420)
Query Neighborhood Hits	451	Target Neighborhood Hits	245	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

NPBL_MOUSE
θ value	θ > 10 (rank : 680)	NC score	0.157426 (rank : 123)
Query Neighborhood Hits	451	Target Neighborhood Hits	1041	Shared Neighborhood Hits	157
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

NRX2A_HUMAN
θ value	θ > 10 (rank : 681)	NC score	0.067568 (rank : 470)
Query Neighborhood Hits	451	Target Neighborhood Hits	614	Shared Neighborhood Hits	127
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NRX2B_HUMAN
θ value	θ > 10 (rank : 682)	NC score	0.104657 (rank : 257)
Query Neighborhood Hits	451	Target Neighborhood Hits	481	Shared Neighborhood Hits	125
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

NSD1_HUMAN
θ value	θ > 10 (rank : 683)	NC score	0.074212 (rank : 414)
Query Neighborhood Hits	451	Target Neighborhood Hits	427	Shared Neighborhood Hits	77
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

NUCKS_HUMAN
θ value	θ > 10 (rank : 684)	NC score	0.075567 (rank : 402)
Query Neighborhood Hits	451	Target Neighborhood Hits	143	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H1E3, Q9H1D6, Q9H723	Gene names	NUCKS1, NUCKS
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (P1).

NUCKS_MOUSE
θ value	θ > 10 (rank : 685)	NC score	0.061366 (rank : 521)
Query Neighborhood Hits	451	Target Neighborhood Hits	114	Shared Neighborhood Hits	18
SwissProt Accessions	Q80XU3, Q8BVD8	Gene names	Nucks1, Nucks
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (JC7).

NUMBL_HUMAN
θ value	θ > 10 (rank : 686)	NC score	0.120226 (rank : 208)
Query Neighborhood Hits	451	Target Neighborhood Hits	394	Shared Neighborhood Hits	119
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

NUP53_HUMAN
θ value	θ > 10 (rank : 687)	NC score	0.063260 (rank : 504)
Query Neighborhood Hits	451	Target Neighborhood Hits	156	Shared Neighborhood Hits	55
SwissProt Accessions	Q8NFH5, Q4ZFZ9, Q53S95, Q8TDJ1	Gene names	NUP35, MP44, NUP53
Domain Architecture	No domain graphic available
Description	Nucleoporin NUP53 (Nuclear pore complex protein Nup53) (Nucleoporin Nup35) (35 kDa nucleoporin) (Mitotic phosphoprotein 44) (MP-44).

OBF1_HUMAN
θ value	θ > 10 (rank : 688)	NC score	0.097071 (rank : 290)
Query Neighborhood Hits	451	Target Neighborhood Hits	203	Shared Neighborhood Hits	74
SwissProt Accessions	Q16633, Q14983	Gene names	POU2AF1, OBF1
Domain Architecture	No domain graphic available
Description	POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (OCT-binding factor 1) (BOB-1) (OCA-B).

OXR1_MOUSE
θ value	θ > 10 (rank : 689)	NC score	0.066229 (rank : 486)
Query Neighborhood Hits	451	Target Neighborhood Hits	516	Shared Neighborhood Hits	59
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

PAF49_HUMAN
θ value	θ > 10 (rank : 690)	NC score	0.069583 (rank : 451)
Query Neighborhood Hits	451	Target Neighborhood Hits	169	Shared Neighborhood Hits	42
SwissProt Accessions	O15446, Q32N11, Q7Z5U2, Q9UPF6	Gene names	CD3EAP, ASE1, CAST, PAF49
Domain Architecture	No domain graphic available
Description	RNA polymerase I-associated factor PAF49 (Anti-sense to ERCC-1 protein) (ASE-1) (CD3-epsilon-associated protein) (CD3E-associated protein) (CAST).

PARM1_MOUSE
θ value	θ > 10 (rank : 691)	NC score	0.061689 (rank : 517)
Query Neighborhood Hits	451	Target Neighborhood Hits	140	Shared Neighborhood Hits	30
SwissProt Accessions	Q923D3, Q3TTV0, Q3UFU4	Gene names
Domain Architecture	No domain graphic available
Description	Protein PARM-1 precursor.

PCQAP_HUMAN
θ value	θ > 10 (rank : 692)	NC score	0.072773 (rank : 424)
Query Neighborhood Hits	451	Target Neighborhood Hits	549	Shared Neighborhood Hits	75
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

PCQAP_MOUSE
θ value	θ > 10 (rank : 693)	NC score	0.057396 (rank : 572)
Query Neighborhood Hits	451	Target Neighborhood Hits	506	Shared Neighborhood Hits	72
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

PDC6I_HUMAN
θ value	θ > 10 (rank : 694)	NC score	0.052090 (rank : 658)
Query Neighborhood Hits	451	Target Neighborhood Hits	278	Shared Neighborhood Hits	54
SwissProt Accessions	Q8WUM4, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5	Gene names	PDCD6IP, AIP1, ALIX, KIAA1375
Domain Architecture
Description	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95).

PDLI7_HUMAN
θ value	θ > 10 (rank : 695)	NC score	0.055291 (rank : 606)
Query Neighborhood Hits	451	Target Neighborhood Hits	547	Shared Neighborhood Hits	112
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

PELP1_MOUSE
θ value	θ > 10 (rank : 696)	NC score	0.137518 (rank : 163)
Query Neighborhood Hits	451	Target Neighborhood Hits	709	Shared Neighborhood Hits	114
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

PER2_MOUSE
θ value	θ > 10 (rank : 697)	NC score	0.078556 (rank : 374)
Query Neighborhood Hits	451	Target Neighborhood Hits	325	Shared Neighborhood Hits	91
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

PER3_HUMAN
θ value	θ > 10 (rank : 698)	NC score	0.087373 (rank : 338)
Query Neighborhood Hits	451	Target Neighborhood Hits	479	Shared Neighborhood Hits	113
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

PF21B_MOUSE
θ value	θ > 10 (rank : 699)	NC score	0.061323 (rank : 522)
Query Neighborhood Hits	451	Target Neighborhood Hits	278	Shared Neighborhood Hits	70
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PHC2_HUMAN
θ value	θ > 10 (rank : 700)	NC score	0.097691 (rank : 287)
Query Neighborhood Hits	451	Target Neighborhood Hits	388	Shared Neighborhood Hits	107
SwissProt Accessions	Q8IXK0, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7	Gene names	PHC2, EDR2, PH2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2).

PHF20_MOUSE
θ value	θ > 10 (rank : 701)	NC score	0.093027 (rank : 312)
Query Neighborhood Hits	451	Target Neighborhood Hits	513	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

PHLA1_HUMAN
θ value	θ > 10 (rank : 702)	NC score	0.055587 (rank : 598)
Query Neighborhood Hits	451	Target Neighborhood Hits	121	Shared Neighborhood Hits	35
SwissProt Accessions	Q8WV24, Q15184, Q2TAN2, Q9NZ17	Gene names	PHLDA1, PHRIP, TDAG51
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family A member 1 (T-cell death- associated gene 51 protein) (Apoptosis-associated nuclear protein) (Proline- and histidine-rich protein) (Proline- and glutamine-rich protein) (PQ-rich protein).

PHLB1_MOUSE
θ value	θ > 10 (rank : 703)	NC score	0.055852 (rank : 596)
Query Neighborhood Hits	451	Target Neighborhood Hits	678	Shared Neighborhood Hits	74
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PKHA4_MOUSE
θ value	θ > 10 (rank : 704)	NC score	0.059276 (rank : 548)
Query Neighborhood Hits	451	Target Neighborhood Hits	202	Shared Neighborhood Hits	32
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PKHA6_MOUSE
θ value	θ > 10 (rank : 705)	NC score	0.067416 (rank : 471)
Query Neighborhood Hits	451	Target Neighborhood Hits	591	Shared Neighborhood Hits	86
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PO121_HUMAN
θ value	θ > 10 (rank : 706)	NC score	0.076223 (rank : 397)
Query Neighborhood Hits	451	Target Neighborhood Hits	344	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

PO121_MOUSE
θ value	θ > 10 (rank : 707)	NC score	0.060957 (rank : 526)
Query Neighborhood Hits	451	Target Neighborhood Hits	345	Shared Neighborhood Hits	55
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

PO6F1_MOUSE
θ value	θ > 10 (rank : 708)	NC score	0.055574 (rank : 599)
Query Neighborhood Hits	451	Target Neighborhood Hits	581	Shared Neighborhood Hits	90
SwissProt Accessions	Q07916, Q91XK3	Gene names	Pou6f1, Emb
Domain Architecture
Description	POU domain, class 6, transcription factor 1 (Octamer-binding transcription factor EMB) (Transcription regulatory protein MCP-1).

PODXL_HUMAN
θ value	θ > 10 (rank : 709)	NC score	0.050422 (rank : 681)
Query Neighborhood Hits	451	Target Neighborhood Hits	191	Shared Neighborhood Hits	26
SwissProt Accessions	O00592	Gene names	PODXL, PCLP, PCLP1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

PPRB_HUMAN
θ value	θ > 10 (rank : 710)	NC score	0.061881 (rank : 515)
Query Neighborhood Hits	451	Target Neighborhood Hits	311	Shared Neighborhood Hits	60
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

PRAX_HUMAN
θ value	θ > 10 (rank : 711)	NC score	0.141639 (rank : 155)
Query Neighborhood Hits	451	Target Neighborhood Hits	215	Shared Neighborhood Hits	54
SwissProt Accessions	Q9BXM0, Q9BXL9, Q9HCF2	Gene names	PRX, KIAA1620
Domain Architecture
Description	Periaxin.

PRAX_MOUSE
θ value	θ > 10 (rank : 712)	NC score	0.130741 (rank : 176)
Query Neighborhood Hits	451	Target Neighborhood Hits	199	Shared Neighborhood Hits	49
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

PRGC2_HUMAN
θ value	θ > 10 (rank : 713)	NC score	0.056119 (rank : 593)
Query Neighborhood Hits	451	Target Neighborhood Hits	272	Shared Neighborhood Hits	64
SwissProt Accessions	Q86YN6, Q86YN3, Q86YN4, Q86YN5, Q8N1N9, Q8TDE4, Q8TDE5	Gene names	PPARGC1B, PERC, PGC1, PGC1B, PPARGC1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta) (PGC-1-related estrogen receptor alpha coactivator) (PPARGC-1-beta) (PGC-1-beta).

PRP5_HUMAN
θ value	θ > 10 (rank : 714)	NC score	0.087393 (rank : 336)
Query Neighborhood Hits	451	Target Neighborhood Hits	108	Shared Neighborhood Hits	31
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

PRPC_HUMAN
θ value	θ > 10 (rank : 715)	NC score	0.082508 (rank : 356)
Query Neighborhood Hits	451	Target Neighborhood Hits	165	Shared Neighborhood Hits	34
SwissProt Accessions	P02810, Q4VBP2, Q53XA2, Q6P2F6	Gene names	PRH1
Domain Architecture	No domain graphic available
Description	Salivary acidic proline-rich phosphoprotein 1/2 precursor (PRP-1/PRP- 2) (Parotid proline-rich protein 1/2) (Pr1/Pr2) (Protein C) (Parotid acidic protein) (Pa) (Parotid isoelectric focusing variant protein) (PIF-S) (Parotid double-band protein) (Db-s) [Contains: Salivary acidic proline-rich phosphoprotein 1/2; Salivary acidic proline-rich phosphoprotein 3/4 (PRP-3/PRP-4) (Protein A) (PIF-F) (Db-F); Peptide P-C].

PRPE_HUMAN
θ value	θ > 10 (rank : 716)	NC score	0.068434 (rank : 461)
Query Neighborhood Hits	451	Target Neighborhood Hits	44	Shared Neighborhood Hits	16
SwissProt Accessions	P02811	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide P-E (IB-9).

PRR13_HUMAN
θ value	θ > 10 (rank : 717)	NC score	0.081389 (rank : 360)
Query Neighborhood Hits	451	Target Neighborhood Hits	105	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

PRR13_MOUSE
θ value	θ > 10 (rank : 718)	NC score	0.072757 (rank : 425)
Query Neighborhood Hits	451	Target Neighborhood Hits	54	Shared Neighborhood Hits	18
SwissProt Accessions	Q9CQJ5, Q3U3U4	Gene names	Prr13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

PRRT3_HUMAN
θ value	θ > 10 (rank : 719)	NC score	0.260434 (rank : 17)
Query Neighborhood Hits	451	Target Neighborhood Hits	998	Shared Neighborhood Hits	229
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

PS1C2_MOUSE
θ value	θ > 10 (rank : 720)	NC score	0.073675 (rank : 419)
Query Neighborhood Hits	451	Target Neighborhood Hits	59	Shared Neighborhood Hits	19
SwissProt Accessions	Q80ZC9	Gene names	Psors1c2, Spr1
Domain Architecture	No domain graphic available
Description	Psoriasis susceptibility 1 candidate gene 2 protein homolog precursor (SPR1 protein).

PTN23_MOUSE
θ value	θ > 10 (rank : 721)	NC score	0.056630 (rank : 587)
Query Neighborhood Hits	451	Target Neighborhood Hits	726	Shared Neighborhood Hits	112
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

PYGO2_HUMAN
θ value	θ > 10 (rank : 722)	NC score	0.051394 (rank : 670)
Query Neighborhood Hits	451	Target Neighborhood Hits	189	Shared Neighborhood Hits	50
SwissProt Accessions	Q9BRQ0, Q8WYZ4, Q96CY2	Gene names	PYGO2
Domain Architecture
Description	Pygopus homolog 2.

R3HD2_MOUSE
θ value	θ > 10 (rank : 723)	NC score	0.066615 (rank : 481)
Query Neighborhood Hits	451	Target Neighborhood Hits	397	Shared Neighborhood Hits	82
SwissProt Accessions	Q80TM6, Q80YB1, Q8BLS5, Q9CW50	Gene names	R3hdm2, Kiaa1002
Domain Architecture
Description	R3H domain-containing protein 2.

R51A1_MOUSE
θ value	θ > 10 (rank : 724)	NC score	0.057028 (rank : 580)
Query Neighborhood Hits	451	Target Neighborhood Hits	164	Shared Neighborhood Hits	26
SwissProt Accessions	Q8C551, O55219, Q8BP36, Q99L94, Q9D0J0	Gene names	Rad51ap1
Domain Architecture	No domain graphic available
Description	RAD51-associated protein 1 (RAD51-interacting protein) (RAB22).

RAI1_MOUSE
θ value	θ > 10 (rank : 725)	NC score	0.064059 (rank : 500)
Query Neighborhood Hits	451	Target Neighborhood Hits	344	Shared Neighborhood Hits	70
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

RBBP6_HUMAN
θ value	θ > 10 (rank : 726)	NC score	0.109367 (rank : 237)
Query Neighborhood Hits	451	Target Neighborhood Hits	1135	Shared Neighborhood Hits	118
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RBBP6_MOUSE
θ value	θ > 10 (rank : 727)	NC score	0.114273 (rank : 222)
Query Neighborhood Hits	451	Target Neighborhood Hits	1014	Shared Neighborhood Hits	113
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

RC3H1_HUMAN
θ value	θ > 10 (rank : 728)	NC score	0.061814 (rank : 516)
Query Neighborhood Hits	451	Target Neighborhood Hits	433	Shared Neighborhood Hits	93
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

RECQ5_HUMAN
θ value	θ > 10 (rank : 729)	NC score	0.052856 (rank : 643)
Query Neighborhood Hits	451	Target Neighborhood Hits	390	Shared Neighborhood Hits	89
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

REXO1_HUMAN
θ value	θ > 10 (rank : 730)	NC score	0.070703 (rank : 440)
Query Neighborhood Hits	451	Target Neighborhood Hits	242	Shared Neighborhood Hits	50
SwissProt Accessions	Q8N1G1, Q9ULT2	Gene names	REXO1, ELOABP1, KIAA1138, TCEB3BP1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Elongin A-binding protein 1) (EloA-BP1) (Transcription elongation factor B polypeptide 3-binding protein 1).

RFIP1_HUMAN
θ value	θ > 10 (rank : 731)	NC score	0.053444 (rank : 635)
Query Neighborhood Hits	451	Target Neighborhood Hits	236	Shared Neighborhood Hits	43
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

RFX1_HUMAN
θ value	θ > 10 (rank : 732)	NC score	0.052042 (rank : 659)
Query Neighborhood Hits	451	Target Neighborhood Hits	256	Shared Neighborhood Hits	69
SwissProt Accessions	P22670	Gene names	RFX1
Domain Architecture
Description	MHC class II regulatory factor RFX1 (RFX) (Enhancer factor C) (EF-C).

RGS3_HUMAN
θ value	θ > 10 (rank : 733)	NC score	0.175852 (rank : 88)
Query Neighborhood Hits	451	Target Neighborhood Hits	1375	Shared Neighborhood Hits	259
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

RGS3_MOUSE
θ value	θ > 10 (rank : 734)	NC score	0.239643 (rank : 35)
Query Neighborhood Hits	451	Target Neighborhood Hits	1621	Shared Neighborhood Hits	287
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

RIMB1_HUMAN
θ value	θ > 10 (rank : 735)	NC score	0.056761 (rank : 584)
Query Neighborhood Hits	451	Target Neighborhood Hits	1479	Shared Neighborhood Hits	134
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RIMS3_HUMAN
θ value	θ > 10 (rank : 736)	NC score	0.050667 (rank : 679)
Query Neighborhood Hits	451	Target Neighborhood Hits	66	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UJD0, Q92511	Gene names	RIMS3, KIAA0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

RIMS3_MOUSE
θ value	θ > 10 (rank : 737)	NC score	0.051467 (rank : 668)
Query Neighborhood Hits	451	Target Neighborhood Hits	67	Shared Neighborhood Hits	7
SwissProt Accessions	Q80U57	Gene names	Rims3, Kiaa0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

RP1L1_HUMAN
θ value	θ > 10 (rank : 738)	NC score	0.085543 (rank : 346)
Query Neighborhood Hits	451	Target Neighborhood Hits	1072	Shared Neighborhood Hits	122
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

RP3A_MOUSE
θ value	θ > 10 (rank : 739)	NC score	0.051606 (rank : 665)
Query Neighborhood Hits	451	Target Neighborhood Hits	510	Shared Neighborhood Hits	105
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

RPB1_HUMAN
θ value	θ > 10 (rank : 740)	NC score	0.062170 (rank : 514)
Query Neighborhood Hits	451	Target Neighborhood Hits	362	Shared Neighborhood Hits	55
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_MOUSE
θ value	θ > 10 (rank : 741)	NC score	0.060427 (rank : 530)
Query Neighborhood Hits	451	Target Neighborhood Hits	363	Shared Neighborhood Hits	53
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPGF1_HUMAN
θ value	θ > 10 (rank : 742)	NC score	0.050565 (rank : 680)
Query Neighborhood Hits	451	Target Neighborhood Hits	262	Shared Neighborhood Hits	75
SwissProt Accessions	Q13905	Gene names	RAPGEF1, GRF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP).

RPTN_MOUSE
θ value	θ > 10 (rank : 743)	NC score	0.051598 (rank : 666)
Query Neighborhood Hits	451	Target Neighborhood Hits	650	Shared Neighborhood Hits	71
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

RSF1_HUMAN
θ value	θ > 10 (rank : 744)	NC score	0.080999 (rank : 364)
Query Neighborhood Hits	451	Target Neighborhood Hits	539	Shared Neighborhood Hits	63
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

RTN4_HUMAN
θ value	θ > 10 (rank : 745)	NC score	0.075081 (rank : 405)
Query Neighborhood Hits	451	Target Neighborhood Hits	357	Shared Neighborhood Hits	81
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

RTN4_MOUSE
θ value	θ > 10 (rank : 746)	NC score	0.078515 (rank : 375)
Query Neighborhood Hits	451	Target Neighborhood Hits	341	Shared Neighborhood Hits	69
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

RTP3_MOUSE
θ value	θ > 10 (rank : 747)	NC score	0.171557 (rank : 96)
Query Neighborhood Hits	451	Target Neighborhood Hits	374	Shared Neighborhood Hits	133
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

RU1C_HUMAN
θ value	θ > 10 (rank : 748)	NC score	0.052456 (rank : 651)
Query Neighborhood Hits	451	Target Neighborhood Hits	81	Shared Neighborhood Hits	20
SwissProt Accessions	P09234	Gene names	SNRPC
Domain Architecture
Description	U1 small nuclear ribonucleoprotein C (U1 snRNP protein C) (U1C protein) (U1-C).

S23IP_MOUSE
θ value	θ > 10 (rank : 749)	NC score	0.068479 (rank : 460)
Query Neighborhood Hits	451	Target Neighborhood Hits	363	Shared Neighborhood Hits	89
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

SAPS1_HUMAN
θ value	θ > 10 (rank : 750)	NC score	0.146606 (rank : 143)
Query Neighborhood Hits	451	Target Neighborhood Hits	704	Shared Neighborhood Hits	166
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

SASH1_MOUSE
θ value	θ > 10 (rank : 751)	NC score	0.078211 (rank : 378)
Query Neighborhood Hits	451	Target Neighborhood Hits	263	Shared Neighborhood Hits	62
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

SC24A_MOUSE
θ value	θ > 10 (rank : 752)	NC score	0.101849 (rank : 269)
Query Neighborhood Hits	451	Target Neighborhood Hits	394	Shared Neighborhood Hits	134
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

SC24C_HUMAN
θ value	θ > 10 (rank : 753)	NC score	0.134428 (rank : 168)
Query Neighborhood Hits	451	Target Neighborhood Hits	662	Shared Neighborhood Hits	156
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

SDC3_HUMAN
θ value	θ > 10 (rank : 754)	NC score	0.058443 (rank : 560)
Query Neighborhood Hits	451	Target Neighborhood Hits	103	Shared Neighborhood Hits	29
SwissProt Accessions	O75056, Q5T1Z6, Q5T1Z7, Q96CT3, Q96PR8	Gene names	SDC3, KIAA0468
Domain Architecture
Description	Syndecan-3 (SYND3).

SDC3_MOUSE
θ value	θ > 10 (rank : 755)	NC score	0.062510 (rank : 512)
Query Neighborhood Hits	451	Target Neighborhood Hits	107	Shared Neighborhood Hits	28
SwissProt Accessions	Q64519, Q3UDD9, Q6ZQA4, Q7TQD4	Gene names	Sdc3, Kiaa0468
Domain Architecture
Description	Syndecan-3 precursor (SYND3).

SELPL_HUMAN
θ value	θ > 10 (rank : 756)	NC score	0.066809 (rank : 478)
Query Neighborhood Hits	451	Target Neighborhood Hits	68	Shared Neighborhood Hits	15
SwissProt Accessions	Q14242, Q12775	Gene names	SELPLG
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand) (CD162 antigen).

SELV_HUMAN
θ value	θ > 10 (rank : 757)	NC score	0.089005 (rank : 328)
Query Neighborhood Hits	451	Target Neighborhood Hits	118	Shared Neighborhood Hits	28
SwissProt Accessions	P59797	Gene names	SELV
Domain Architecture	No domain graphic available
Description	Selenoprotein V.

SEPT9_HUMAN
θ value	θ > 10 (rank : 758)	NC score	0.108519 (rank : 243)
Query Neighborhood Hits	451	Target Neighborhood Hits	706	Shared Neighborhood Hits	166
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

SETBP_HUMAN
θ value	θ > 10 (rank : 759)	NC score	0.080246 (rank : 368)
Query Neighborhood Hits	451	Target Neighborhood Hits	305	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y6X0, Q9UEF3	Gene names	SETBP1, KIAA0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

SETBP_MOUSE
θ value	θ > 10 (rank : 760)	NC score	0.087303 (rank : 339)
Query Neighborhood Hits	451	Target Neighborhood Hits	352	Shared Neighborhood Hits	86
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

SETD2_HUMAN
θ value	θ > 10 (rank : 761)	NC score	0.060141 (rank : 537)
Query Neighborhood Hits	451	Target Neighborhood Hits	412	Shared Neighborhood Hits	57
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SETD8_MOUSE
θ value	θ > 10 (rank : 762)	NC score	0.053566 (rank : 634)
Query Neighborhood Hits	451	Target Neighborhood Hits	131	Shared Neighborhood Hits	33
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).

SF01_HUMAN
θ value	θ > 10 (rank : 763)	NC score	0.055876 (rank : 595)
Query Neighborhood Hits	451	Target Neighborhood Hits	287	Shared Neighborhood Hits	65
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

SF01_MOUSE
θ value	θ > 10 (rank : 764)	NC score	0.051792 (rank : 662)
Query Neighborhood Hits	451	Target Neighborhood Hits	240	Shared Neighborhood Hits	58
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

SF3A1_HUMAN
θ value	θ > 10 (rank : 765)	NC score	0.096532 (rank : 293)
Query Neighborhood Hits	451	Target Neighborhood Hits	199	Shared Neighborhood Hits	46
SwissProt Accessions	Q15459	Gene names	SF3A1, SAP114
Domain Architecture
Description	Splicing factor 3 subunit 1 (Spliceosome-associated protein 114) (SAP 114) (SF3a120).

SF3B1_HUMAN
θ value	θ > 10 (rank : 766)	NC score	0.069493 (rank : 452)
Query Neighborhood Hits	451	Target Neighborhood Hits	341	Shared Neighborhood Hits	58
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_MOUSE
θ value	θ > 10 (rank : 767)	NC score	0.070824 (rank : 438)
Query Neighborhood Hits	451	Target Neighborhood Hits	352	Shared Neighborhood Hits	62
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SFR15_HUMAN
θ value	θ > 10 (rank : 768)	NC score	0.098429 (rank : 282)
Query Neighborhood Hits	451	Target Neighborhood Hits	368	Shared Neighborhood Hits	77
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

SFRIP_HUMAN
θ value	θ > 10 (rank : 769)	NC score	0.129422 (rank : 179)
Query Neighborhood Hits	451	Target Neighborhood Hits	530	Shared Neighborhood Hits	91
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

SFRS8_HUMAN
θ value	θ > 10 (rank : 770)	NC score	0.058322 (rank : 561)
Query Neighborhood Hits	451	Target Neighborhood Hits	166	Shared Neighborhood Hits	29
SwissProt Accessions	Q12872	Gene names	SFRS8, SWAP
Domain Architecture
Description	Splicing factor, arginine/serine-rich 8 (Suppressor of white apricot protein homolog).

SGIP1_HUMAN
θ value	θ > 10 (rank : 771)	NC score	0.055158 (rank : 608)
Query Neighborhood Hits	451	Target Neighborhood Hits	198	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SGIP1_MOUSE
θ value	θ > 10 (rank : 772)	NC score	0.077752 (rank : 383)
Query Neighborhood Hits	451	Target Neighborhood Hits	180	Shared Neighborhood Hits	40
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SHAN1_HUMAN
θ value	θ > 10 (rank : 773)	NC score	0.064348 (rank : 499)
Query Neighborhood Hits	451	Target Neighborhood Hits	1041	Shared Neighborhood Hits	104
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SMR3A_HUMAN
θ value	θ > 10 (rank : 774)	NC score	0.077754 (rank : 382)
Query Neighborhood Hits	451	Target Neighborhood Hits	93	Shared Neighborhood Hits	35
SwissProt Accessions	Q99954	Gene names	SMR3A, PBI, PROL5
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog A precursor (Proline-rich protein 5) (Proline-rich protein PBI).

SMRC2_HUMAN
θ value	θ > 10 (rank : 775)	NC score	0.058048 (rank : 566)
Query Neighborhood Hits	451	Target Neighborhood Hits	499	Shared Neighborhood Hits	71
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

SMRC2_MOUSE
θ value	θ > 10 (rank : 776)	NC score	0.059298 (rank : 547)
Query Neighborhood Hits	451	Target Neighborhood Hits	487	Shared Neighborhood Hits	67
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

SNPC4_HUMAN
θ value	θ > 10 (rank : 777)	NC score	0.142476 (rank : 154)
Query Neighborhood Hits	451	Target Neighborhood Hits	589	Shared Neighborhood Hits	146
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

SOX13_HUMAN
θ value	θ > 10 (rank : 778)	NC score	0.095972 (rank : 297)
Query Neighborhood Hits	451	Target Neighborhood Hits	464	Shared Neighborhood Hits	134
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

SOX13_MOUSE
θ value	θ > 10 (rank : 779)	NC score	0.076375 (rank : 395)
Query Neighborhood Hits	451	Target Neighborhood Hits	495	Shared Neighborhood Hits	130
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

SOX30_HUMAN
θ value	θ > 10 (rank : 780)	NC score	0.059049 (rank : 551)
Query Neighborhood Hits	451	Target Neighborhood Hits	305	Shared Neighborhood Hits	69
SwissProt Accessions	O94993, O94995, Q8IYX6	Gene names	SOX30
Domain Architecture
Description	Transcription factor SOX-30.

SPR1B_HUMAN
θ value	θ > 10 (rank : 781)	NC score	0.072597 (rank : 428)
Query Neighborhood Hits	451	Target Neighborhood Hits	102	Shared Neighborhood Hits	30
SwissProt Accessions	P22528, P22529, P22530, Q5T524	Gene names	SPRR1B
Domain Architecture	No domain graphic available
Description	Cornifin B (Small proline-rich protein IB) (SPR-IB) (14.9 kDa pancornulin).

SPR2D_MOUSE
θ value	θ > 10 (rank : 782)	NC score	0.051523 (rank : 667)
Query Neighborhood Hits	451	Target Neighborhood Hits	61	Shared Neighborhood Hits	14
SwissProt Accessions	O70555	Gene names	Sprr2d
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D.

SPR2H_MOUSE
θ value	θ > 10 (rank : 783)	NC score	0.075003 (rank : 407)
Query Neighborhood Hits	451	Target Neighborhood Hits	82	Shared Neighborhood Hits	23
SwissProt Accessions	O70559	Gene names	Sprr2h
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2H.

SPRR3_HUMAN
θ value	θ > 10 (rank : 784)	NC score	0.192091 (rank : 74)
Query Neighborhood Hits	451	Target Neighborhood Hits	102	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UBC9, O75597, Q4ZGI7, Q5T525, Q8NET7, Q9UDG3	Gene names	SPRR3, SPRC
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta) (Esophagin) (22 kDa pancornulin).

SPRR3_MOUSE
θ value	θ > 10 (rank : 785)	NC score	0.124962 (rank : 188)
Query Neighborhood Hits	451	Target Neighborhood Hits	106	Shared Neighborhood Hits	34
SwissProt Accessions	O09116	Gene names	Sprr3
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta).

SPT5H_HUMAN
θ value	θ > 10 (rank : 786)	NC score	0.107188 (rank : 249)
Query Neighborhood Hits	451	Target Neighborhood Hits	436	Shared Neighborhood Hits	96
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

SPT5H_MOUSE
θ value	θ > 10 (rank : 787)	NC score	0.110230 (rank : 232)
Query Neighborhood Hits	451	Target Neighborhood Hits	437	Shared Neighborhood Hits	98
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

SRBP1_MOUSE
θ value	θ > 10 (rank : 788)	NC score	0.062660 (rank : 511)
Query Neighborhood Hits	451	Target Neighborhood Hits	384	Shared Neighborhood Hits	87
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

SSBP4_HUMAN
θ value	θ > 10 (rank : 789)	NC score	0.132534 (rank : 173)
Query Neighborhood Hits	451	Target Neighborhood Hits	753	Shared Neighborhood Hits	161
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

SVIL_MOUSE
θ value	θ > 10 (rank : 790)	NC score	0.074541 (rank : 411)
Query Neighborhood Hits	451	Target Neighborhood Hits	439	Shared Neighborhood Hits	82
SwissProt Accessions	Q8K4L3	Gene names	Svil
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

SYN1_MOUSE
θ value	θ > 10 (rank : 791)	NC score	0.077304 (rank : 392)
Query Neighborhood Hits	451	Target Neighborhood Hits	363	Shared Neighborhood Hits	77
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

SYNJ2_HUMAN
θ value	θ > 10 (rank : 792)	NC score	0.077111 (rank : 393)
Query Neighborhood Hits	451	Target Neighborhood Hits	136	Shared Neighborhood Hits	40
SwissProt Accessions	O15056, Q5TA13, Q5TA16, Q5TA19, Q86XK0, Q8IZA8, Q9H226	Gene names	SYNJ2, KIAA0348
Domain Architecture	No domain graphic available
Description	Synaptojanin-2 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 2).

SYNJ2_MOUSE
θ value	θ > 10 (rank : 793)	NC score	0.052467 (rank : 650)
Query Neighborhood Hits	451	Target Neighborhood Hits	87	Shared Neighborhood Hits	22
SwissProt Accessions	Q9D2G5, O35404, O88399, O88400, O88401, O88402, O88403, O88404	Gene names	Synj2, Kiaa0348
Domain Architecture
Description	Synaptojanin-2 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 2).

SYNPO_HUMAN
θ value	θ > 10 (rank : 794)	NC score	0.076025 (rank : 399)
Query Neighborhood Hits	451	Target Neighborhood Hits	281	Shared Neighborhood Hits	75
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

SYNPO_MOUSE
θ value	θ > 10 (rank : 795)	NC score	0.075435 (rank : 403)
Query Neighborhood Hits	451	Target Neighborhood Hits	242	Shared Neighborhood Hits	64
SwissProt Accessions	Q8CC35, Q99JI0	Gene names	Synpo, Kiaa1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

SYP2L_HUMAN
θ value	θ > 10 (rank : 796)	NC score	0.054272 (rank : 623)
Query Neighborhood Hits	451	Target Neighborhood Hits	400	Shared Neighborhood Hits	79
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

T22D2_HUMAN
θ value	θ > 10 (rank : 797)	NC score	0.075054 (rank : 406)
Query Neighborhood Hits	451	Target Neighborhood Hits	250	Shared Neighborhood Hits	55
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

T22D4_HUMAN
θ value	θ > 10 (rank : 798)	NC score	0.125767 (rank : 187)
Query Neighborhood Hits	451	Target Neighborhood Hits	403	Shared Neighborhood Hits	108
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

T2FA_HUMAN
θ value	θ > 10 (rank : 799)	NC score	0.054782 (rank : 615)
Query Neighborhood Hits	451	Target Neighborhood Hits	228	Shared Neighborhood Hits	30
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

TAB3_MOUSE
θ value	θ > 10 (rank : 800)	NC score	0.051640 (rank : 664)
Query Neighborhood Hits	451	Target Neighborhood Hits	273	Shared Neighborhood Hits	67
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

TACC2_HUMAN
θ value	θ > 10 (rank : 801)	NC score	0.058938 (rank : 553)
Query Neighborhood Hits	451	Target Neighborhood Hits	856	Shared Neighborhood Hits	97
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

TACC2_MOUSE
θ value	θ > 10 (rank : 802)	NC score	0.052523 (rank : 649)
Query Neighborhood Hits	451	Target Neighborhood Hits	774	Shared Neighborhood Hits	82
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

TAF3_MOUSE
θ value	θ > 10 (rank : 803)	NC score	0.073077 (rank : 421)
Query Neighborhood Hits	451	Target Neighborhood Hits	463	Shared Neighborhood Hits	53
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TAF4_HUMAN
θ value	θ > 10 (rank : 804)	NC score	0.138346 (rank : 162)
Query Neighborhood Hits	451	Target Neighborhood Hits	687	Shared Neighborhood Hits	102
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

TAU_HUMAN
θ value	θ > 10 (rank : 805)	NC score	0.108832 (rank : 241)
Query Neighborhood Hits	451	Target Neighborhood Hits	448	Shared Neighborhood Hits	111
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TAU_MOUSE
θ value	θ > 10 (rank : 806)	NC score	0.116295 (rank : 215)
Query Neighborhood Hits	451	Target Neighborhood Hits	502	Shared Neighborhood Hits	114
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TB182_HUMAN
θ value	θ > 10 (rank : 807)	NC score	0.061109 (rank : 525)
Query Neighborhood Hits	451	Target Neighborhood Hits	414	Shared Neighborhood Hits	58
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

TCAL5_HUMAN
θ value	θ > 10 (rank : 808)	NC score	0.051950 (rank : 660)
Query Neighborhood Hits	451	Target Neighborhood Hits	806	Shared Neighborhood Hits	72
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

TCF20_MOUSE
θ value	θ > 10 (rank : 809)	NC score	0.052152 (rank : 655)
Query Neighborhood Hits	451	Target Neighborhood Hits	396	Shared Neighborhood Hits	60
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

TCGAP_HUMAN
θ value	θ > 10 (rank : 810)	NC score	0.110054 (rank : 234)
Query Neighborhood Hits	451	Target Neighborhood Hits	872	Shared Neighborhood Hits	169
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TCOF_HUMAN
θ value	θ > 10 (rank : 811)	NC score	0.100220 (rank : 274)
Query Neighborhood Hits	451	Target Neighborhood Hits	543	Shared Neighborhood Hits	76
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

TCOF_MOUSE
θ value	θ > 10 (rank : 812)	NC score	0.102119 (rank : 268)
Query Neighborhood Hits	451	Target Neighborhood Hits	471	Shared Neighborhood Hits	71
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

TCRG1_HUMAN
θ value	θ > 10 (rank : 813)	NC score	0.069439 (rank : 454)
Query Neighborhood Hits	451	Target Neighborhood Hits	929	Shared Neighborhood Hits	106
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TCRG1_MOUSE
θ value	θ > 10 (rank : 814)	NC score	0.070559 (rank : 443)
Query Neighborhood Hits	451	Target Neighborhood Hits	947	Shared Neighborhood Hits	107
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

TGON1_MOUSE
θ value	θ > 10 (rank : 815)	NC score	0.074137 (rank : 415)
Query Neighborhood Hits	451	Target Neighborhood Hits	243	Shared Neighborhood Hits	50
SwissProt Accessions	Q62313	Gene names	Tgoln1, Ttgn1
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 1 precursor (TGN38A).

TGON2_HUMAN
θ value	θ > 10 (rank : 816)	NC score	0.186391 (rank : 79)
Query Neighborhood Hits	451	Target Neighborhood Hits	1037	Shared Neighborhood Hits	157
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TGON2_MOUSE
θ value	θ > 10 (rank : 817)	NC score	0.071903 (rank : 434)
Query Neighborhood Hits	451	Target Neighborhood Hits	277	Shared Neighborhood Hits	55
SwissProt Accessions	Q62314	Gene names	Tgoln2, Ttgn2
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 2 precursor (TGN38B).

TM108_HUMAN
θ value	θ > 10 (rank : 818)	NC score	0.070497 (rank : 444)
Query Neighborhood Hits	451	Target Neighborhood Hits	166	Shared Neighborhood Hits	51
SwissProt Accessions	Q6UXF1, Q9BQH1, Q9BW81, Q9C0H3	Gene names	TMEM108, KIAA1690
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

TM108_MOUSE
θ value	θ > 10 (rank : 819)	NC score	0.103764 (rank : 260)
Query Neighborhood Hits	451	Target Neighborhood Hits	336	Shared Neighborhood Hits	83
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

TMAP1_HUMAN
θ value	θ > 10 (rank : 820)	NC score	0.080014 (rank : 370)
Query Neighborhood Hits	451	Target Neighborhood Hits	140	Shared Neighborhood Hits	27
SwissProt Accessions	P84157	Gene names	TMAP1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

TP53B_HUMAN
θ value	θ > 10 (rank : 821)	NC score	0.058569 (rank : 556)
Query Neighborhood Hits	451	Target Neighborhood Hits	413	Shared Neighborhood Hits	67
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TP53B_MOUSE
θ value	θ > 10 (rank : 822)	NC score	0.135187 (rank : 166)
Query Neighborhood Hits	451	Target Neighborhood Hits	644	Shared Neighborhood Hits	119
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TPO_MOUSE
θ value	θ > 10 (rank : 823)	NC score	0.133068 (rank : 170)
Query Neighborhood Hits	451	Target Neighborhood Hits	258	Shared Neighborhood Hits	104
SwissProt Accessions	P40226	Gene names	Thpo
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

TR150_MOUSE
θ value	θ > 10 (rank : 824)	NC score	0.057452 (rank : 571)
Query Neighborhood Hits	451	Target Neighborhood Hits	468	Shared Neighborhood Hits	55
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

TULP4_MOUSE
θ value	θ > 10 (rank : 825)	NC score	0.051671 (rank : 663)
Query Neighborhood Hits	451	Target Neighborhood Hits	247	Shared Neighborhood Hits	48
SwissProt Accessions	Q9JIL5, Q8CA75, Q922C2	Gene names	Tulp4, Tusp
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

TXLNB_HUMAN
θ value	θ > 10 (rank : 826)	NC score	0.057318 (rank : 574)
Query Neighborhood Hits	451	Target Neighborhood Hits	912	Shared Neighborhood Hits	117
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

TXND2_MOUSE
θ value	θ > 10 (rank : 827)	NC score	0.129301 (rank : 180)
Query Neighborhood Hits	451	Target Neighborhood Hits	828	Shared Neighborhood Hits	92
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

UBP42_HUMAN
θ value	θ > 10 (rank : 828)	NC score	0.059821 (rank : 540)
Query Neighborhood Hits	451	Target Neighborhood Hits	445	Shared Neighborhood Hits	79
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

VASP_HUMAN
θ value	θ > 10 (rank : 829)	NC score	0.053929 (rank : 630)
Query Neighborhood Hits	451	Target Neighborhood Hits	201	Shared Neighborhood Hits	45
SwissProt Accessions	P50552, Q6PIZ1, Q93035	Gene names	VASP
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

VASP_MOUSE
θ value	θ > 10 (rank : 830)	NC score	0.054240 (rank : 624)
Query Neighborhood Hits	451	Target Neighborhood Hits	195	Shared Neighborhood Hits	46
SwissProt Accessions	P70460, Q3TAP0, Q3TCD2, Q3U0C2, Q3UDF1, Q91VD2, Q9R214	Gene names	Vasp
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

VCX1_HUMAN
θ value	θ > 10 (rank : 831)	NC score	0.098009 (rank : 285)
Query Neighborhood Hits	451	Target Neighborhood Hits	129	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H320, Q9P0H3	Gene names	VCX, VCX1, VCX10R, VCXB1
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 1 (VCX-B1 protein) (Variably charged protein X-B1) (Variable charge protein on X with ten repeats) (VCX- 10r).

VCX2_HUMAN
θ value	θ > 10 (rank : 832)	NC score	0.085087 (rank : 347)
Query Neighborhood Hits	451	Target Neighborhood Hits	38	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H322, Q9P0H5	Gene names	VCX2, VCX2R, VCXB
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 2 (VCX-B protein) (Variably charged protein X-B) (Variable charge protein on X with two repeats) (VCX-2r).

VCX3_HUMAN
θ value	θ > 10 (rank : 833)	NC score	0.109215 (rank : 240)
Query Neighborhood Hits	451	Target Neighborhood Hits	105	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NNX9, Q9P0H4	Gene names	VCX3A, VCX3, VCX8R, VCXA
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 3 (VCX-A protein) (Variably charged protein X-A) (Variable charge protein on X with eight repeats) (VCX- 8r).

VCXC_HUMAN
θ value	θ > 10 (rank : 834)	NC score	0.114393 (rank : 220)
Query Neighborhood Hits	451	Target Neighborhood Hits	139	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H321	Gene names	VCXC
Domain Architecture	No domain graphic available
Description	VCX-C protein (Variably charged protein X-C).

WBS14_MOUSE
θ value	θ > 10 (rank : 835)	NC score	0.070103 (rank : 446)
Query Neighborhood Hits	451	Target Neighborhood Hits	171	Shared Neighborhood Hits	38
SwissProt Accessions	Q99MZ3, Q99MY9, Q99MZ0, Q99MZ1, Q99MZ2, Q9JLM5	Gene names	Mlxipl, Mio, Wbscr14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein homolog (Mlx interactor) (MLX-interacting protein-like).

WDR46_MOUSE
θ value	θ > 10 (rank : 836)	NC score	0.079140 (rank : 373)
Query Neighborhood Hits	451	Target Neighborhood Hits	243	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Z0H1	Gene names	Wdr46, Bing4
Domain Architecture
Description	WD repeat protein 46 (WD repeat protein BING4).

YETS2_MOUSE
θ value	θ > 10 (rank : 837)	NC score	0.053130 (rank : 638)
Query Neighborhood Hits	451	Target Neighborhood Hits	278	Shared Neighborhood Hits	47
SwissProt Accessions	Q3TUF7, Q6PGF8, Q80TI2, Q8CG86	Gene names	Yeats2, Kiaa1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

YTDC1_HUMAN
θ value	θ > 10 (rank : 838)	NC score	0.077710 (rank : 384)
Query Neighborhood Hits	451	Target Neighborhood Hits	458	Shared Neighborhood Hits	46
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

ZAN_HUMAN
θ value	θ > 10 (rank : 839)	NC score	0.070476 (rank : 445)
Query Neighborhood Hits	451	Target Neighborhood Hits	679	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

ZAN_MOUSE
θ value	θ > 10 (rank : 840)	NC score	0.057938 (rank : 568)
Query Neighborhood Hits	451	Target Neighborhood Hits	808	Shared Neighborhood Hits	40
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

ZAR1_MOUSE
θ value	θ > 10 (rank : 841)	NC score	0.053126 (rank : 639)
Query Neighborhood Hits	451	Target Neighborhood Hits	254	Shared Neighborhood Hits	46
SwissProt Accessions	Q80SU3	Gene names	Zar1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

ZC313_HUMAN
θ value	θ > 10 (rank : 842)	NC score	0.075117 (rank : 404)
Query Neighborhood Hits	451	Target Neighborhood Hits	772	Shared Neighborhood Hits	76
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

ZCH11_HUMAN
θ value	θ > 10 (rank : 843)	NC score	0.053073 (rank : 640)
Query Neighborhood Hits	451	Target Neighborhood Hits	278	Shared Neighborhood Hits	64
SwissProt Accessions	Q5TAX3, Q12764, Q5TAX4, Q86XZ3	Gene names	ZCCHC11, KIAA0191
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 11.

ZCHC5_HUMAN
θ value	θ > 10 (rank : 844)	NC score	0.051171 (rank : 673)
Query Neighborhood Hits	451	Target Neighborhood Hits	75	Shared Neighborhood Hits	18
SwissProt Accessions	Q8N8U3	Gene names	ZCCHC5
Domain Architecture
Description	Zinc finger CCHC domain-containing protein 5.

ZCPW1_MOUSE
θ value	θ > 10 (rank : 845)	NC score	0.081009 (rank : 363)
Query Neighborhood Hits	451	Target Neighborhood Hits	307	Shared Neighborhood Hits	55
SwissProt Accessions	Q6IR42	Gene names	Zcwpw1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1 homolog.

ZIMP7_MOUSE
θ value	θ > 10 (rank : 846)	NC score	0.122618 (rank : 197)
Query Neighborhood Hits	451	Target Neighborhood Hits	566	Shared Neighborhood Hits	128
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

ZN207_HUMAN
θ value	θ > 10 (rank : 847)	NC score	0.091469 (rank : 318)
Query Neighborhood Hits	451	Target Neighborhood Hits	326	Shared Neighborhood Hits	53
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

ZN318_MOUSE
θ value	θ > 10 (rank : 848)	NC score	0.053358 (rank : 636)
Query Neighborhood Hits	451	Target Neighborhood Hits	642	Shared Neighborhood Hits	78
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

ZN385_HUMAN
θ value	θ > 10 (rank : 849)	NC score	0.113419 (rank : 224)
Query Neighborhood Hits	451	Target Neighborhood Hits	614	Shared Neighborhood Hits	127
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

ZN645_HUMAN
θ value	θ > 10 (rank : 850)	NC score	0.108814 (rank : 242)
Query Neighborhood Hits	451	Target Neighborhood Hits	265	Shared Neighborhood Hits	89
SwissProt Accessions	Q8N7E2, Q6DJY9	Gene names	ZNF645
Domain Architecture	No domain graphic available
Description	Zinc finger protein 645.

ZN750_MOUSE
θ value	θ > 10 (rank : 851)	NC score	0.113814 (rank : 223)
Query Neighborhood Hits	451	Target Neighborhood Hits	346	Shared Neighborhood Hits	84
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

Hits sorted by NC score

FA47A_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	451	Target Neighborhood Hits	451	Shared Neighborhood Hits	451
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

FA47B_HUMAN
NC score	0.819209 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	451	Target Neighborhood Hits	431	Shared Neighborhood Hits	215
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

SRRM1_MOUSE
NC score	0.356752 (rank : 3)	θ value	1.99992e-07 (rank : 7)
Query Neighborhood Hits	451	Target Neighborhood Hits	966	Shared Neighborhood Hits	205
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SON_HUMAN
NC score	0.342561 (rank : 4)	θ value	5.81887e-07 (rank : 11)
Query Neighborhood Hits	451	Target Neighborhood Hits	1568	Shared Neighborhood Hits	275
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

TARSH_HUMAN
NC score	0.340602 (rank : 5)	θ value	0.00020696 (rank : 28)
Query Neighborhood Hits	451	Target Neighborhood Hits	768	Shared Neighborhood Hits	196
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

NACAM_MOUSE
NC score	0.330856 (rank : 6)	θ value	5.44631e-05 (rank : 16)
Query Neighborhood Hits	451	Target Neighborhood Hits	1866	Shared Neighborhood Hits	290
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

SRRM1_HUMAN
NC score	0.323403 (rank : 7)	θ value	3.64472e-09 (rank : 3)
Query Neighborhood Hits	451	Target Neighborhood Hits	690	Shared Neighborhood Hits	129
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

MDC1_HUMAN
NC score	0.297607 (rank : 8)	θ value	0.365318 (rank : 154)
Query Neighborhood Hits	451	Target Neighborhood Hits	1446	Shared Neighborhood Hits	240
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

SON_MOUSE
NC score	0.294361 (rank : 9)	θ value	9.29e-05 (rank : 21)
Query Neighborhood Hits	451	Target Neighborhood Hits	957	Shared Neighborhood Hits	189
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

WASIP_HUMAN
NC score	0.280700 (rank : 10)	θ value	7.1131e-05 (rank : 17)
Query Neighborhood Hits	451	Target Neighborhood Hits	458	Shared Neighborhood Hits	99
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

SRRM2_MOUSE
NC score	0.273090 (rank : 11)	θ value	0.000786445 (rank : 40)
Query Neighborhood Hits	451	Target Neighborhood Hits	1470	Shared Neighborhood Hits	219
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

OGFR_HUMAN
NC score	0.272128 (rank : 12)	θ value	0.0431538 (rank : 83)
Query Neighborhood Hits	451	Target Neighborhood Hits	1582	Shared Neighborhood Hits	253
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

MDC1_MOUSE
NC score	0.272062 (rank : 13)	θ value	θ > 10 (rank : 642)
Query Neighborhood Hits	451	Target Neighborhood Hits	998	Shared Neighborhood Hits	217
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

TXND2_HUMAN
NC score	0.269274 (rank : 14)	θ value	0.000121331 (rank : 23)
Query Neighborhood Hits	451	Target Neighborhood Hits	793	Shared Neighborhood Hits	157
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

WASIP_MOUSE
NC score	0.264910 (rank : 15)	θ value	0.000270298 (rank : 30)
Query Neighborhood Hits	451	Target Neighborhood Hits	392	Shared Neighborhood Hits	93
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

PRR12_HUMAN
NC score	0.262651 (rank : 16)	θ value	0.00390308 (rank : 54)
Query Neighborhood Hits	451	Target Neighborhood Hits	460	Shared Neighborhood Hits	103
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

PRRT3_HUMAN
NC score	0.260434 (rank : 17)	θ value	θ > 10 (rank : 719)
Query Neighborhood Hits	451	Target Neighborhood Hits	998	Shared Neighborhood Hits	229
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

PRG4_HUMAN
NC score	0.259870 (rank : 18)	θ value	4.0297e-08 (rank : 5)
Query Neighborhood Hits	451	Target Neighborhood Hits	764	Shared Neighborhood Hits	116
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

MUC1_HUMAN
NC score	0.256642 (rank : 19)	θ value	θ > 10 (rank : 657)
Query Neighborhood Hits	451	Target Neighborhood Hits	975	Shared Neighborhood Hits	197
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

SRRM2_HUMAN
NC score	0.253825 (rank : 20)	θ value	1.43324e-05 (rank : 14)
Query Neighborhood Hits	451	Target Neighborhood Hits	1296	Shared Neighborhood Hits	194
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

K1802_MOUSE
NC score	0.252487 (rank : 21)	θ value	0.00102713 (rank : 43)
Query Neighborhood Hits	451	Target Neighborhood Hits	1596	Shared Neighborhood Hits	249
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

IWS1_MOUSE
NC score	0.252042 (rank : 22)	θ value	3.41135e-07 (rank : 8)
Query Neighborhood Hits	451	Target Neighborhood Hits	1258	Shared Neighborhood Hits	175
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

LCP2_HUMAN
NC score	0.249713 (rank : 23)	θ value	0.125558 (rank : 104)
Query Neighborhood Hits	451	Target Neighborhood Hits	531	Shared Neighborhood Hits	171
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

FMN1A_MOUSE
NC score	0.247152 (rank : 24)	θ value	0.000461057 (rank : 33)
Query Neighborhood Hits	451	Target Neighborhood Hits	423	Shared Neighborhood Hits	98
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

SPR1B_MOUSE
NC score	0.246960 (rank : 25)	θ value	0.47712 (rank : 167)
Query Neighborhood Hits	451	Target Neighborhood Hits	395	Shared Neighborhood Hits	143
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

PCLO_HUMAN
NC score	0.246521 (rank : 26)	θ value	0.00134147 (rank : 45)
Query Neighborhood Hits	451	Target Neighborhood Hits	2046	Shared Neighborhood Hits	294
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PRG4_MOUSE
NC score	0.246096 (rank : 27)	θ value	1.17247e-07 (rank : 6)
Query Neighborhood Hits	451	Target Neighborhood Hits	624	Shared Neighborhood Hits	100
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

IWS1_HUMAN
NC score	0.246085 (rank : 28)	θ value	3.08544e-08 (rank : 4)
Query Neighborhood Hits	451	Target Neighborhood Hits	1241	Shared Neighborhood Hits	155
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

CN155_HUMAN
NC score	0.245912 (rank : 29)	θ value	0.00102713 (rank : 41)
Query Neighborhood Hits	451	Target Neighborhood Hits	385	Shared Neighborhood Hits	80
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

FMN1B_MOUSE
NC score	0.244883 (rank : 30)	θ value	0.000461057 (rank : 34)
Query Neighborhood Hits	451	Target Neighborhood Hits	447	Shared Neighborhood Hits	99
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

FMN2_MOUSE
NC score	0.242987 (rank : 31)	θ value	0.00390308 (rank : 53)
Query Neighborhood Hits	451	Target Neighborhood Hits	349	Shared Neighborhood Hits	101
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

MAGE1_HUMAN
NC score	0.242315 (rank : 32)	θ value	0.0330416 (rank : 73)
Query Neighborhood Hits	451	Target Neighborhood Hits	1389	Shared Neighborhood Hits	236
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

RAPH1_HUMAN
NC score	0.240292 (rank : 33)	θ value	3.77169e-06 (rank : 13)
Query Neighborhood Hits	451	Target Neighborhood Hits	593	Shared Neighborhood Hits	129
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

WASL_MOUSE
NC score	0.240104 (rank : 34)	θ value	0.00869519 (rank : 64)
Query Neighborhood Hits	451	Target Neighborhood Hits	339	Shared Neighborhood Hits	85
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

RGS3_MOUSE
NC score	0.239643 (rank : 35)	θ value	θ > 10 (rank : 734)
Query Neighborhood Hits	451	Target Neighborhood Hits	1621	Shared Neighborhood Hits	287
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

FMN2_HUMAN
NC score	0.239335 (rank : 36)	θ value	0.000270298 (rank : 29)
Query Neighborhood Hits	451	Target Neighborhood Hits	484	Shared Neighborhood Hits	97
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

BSN_MOUSE
NC score	0.238434 (rank : 37)	θ value	3.0926 (rank : 290)
Query Neighborhood Hits	451	Target Neighborhood Hits	2057	Shared Neighborhood Hits	285
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CEL_HUMAN
NC score	0.237389 (rank : 38)	θ value	0.000121331 (rank : 22)
Query Neighborhood Hits	451	Target Neighborhood Hits	896	Shared Neighborhood Hits	213
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

CD2_HUMAN
NC score	0.233870 (rank : 39)	θ value	0.813845 (rank : 184)
Query Neighborhood Hits	451	Target Neighborhood Hits	504	Shared Neighborhood Hits	161
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

LAD1_MOUSE
NC score	0.230937 (rank : 40)	θ value	0.365318 (rank : 152)
Query Neighborhood Hits	451	Target Neighborhood Hits	391	Shared Neighborhood Hits	110
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

PCLO_MOUSE
NC score	0.229893 (rank : 41)	θ value	0.125558 (rank : 107)
Query Neighborhood Hits	451	Target Neighborhood Hits	2275	Shared Neighborhood Hits	286
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

CJ078_MOUSE
NC score	0.224594 (rank : 42)	θ value	0.125558 (rank : 103)
Query Neighborhood Hits	451	Target Neighborhood Hits	559	Shared Neighborhood Hits	100
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

WASL_HUMAN
NC score	0.222498 (rank : 43)	θ value	0.0431538 (rank : 84)
Query Neighborhood Hits	451	Target Neighborhood Hits	312	Shared Neighborhood Hits	80
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

NCOA6_HUMAN
NC score	0.221099 (rank : 44)	θ value	θ > 10 (rank : 666)
Query Neighborhood Hits	451	Target Neighborhood Hits	1202	Shared Neighborhood Hits	237
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

SELPL_MOUSE
NC score	0.216029 (rank : 45)	θ value	3.0926 (rank : 313)
Query Neighborhood Hits	451	Target Neighborhood Hits	588	Shared Neighborhood Hits	152
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

ALEX_HUMAN
NC score	0.215762 (rank : 46)	θ value	0.0431538 (rank : 81)
Query Neighborhood Hits	451	Target Neighborhood Hits	361	Shared Neighborhood Hits	100
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

MAP1B_HUMAN
NC score	0.215079 (rank : 47)	θ value	0.00020696 (rank : 25)
Query Neighborhood Hits	451	Target Neighborhood Hits	903	Shared Neighborhood Hits	123
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

MUC7_HUMAN
NC score	0.214673 (rank : 48)	θ value	0.0330416 (rank : 74)
Query Neighborhood Hits	451	Target Neighborhood Hits	538	Shared Neighborhood Hits	88
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

ATN1_HUMAN
NC score	0.214115 (rank : 49)	θ value	0.000602161 (rank : 35)
Query Neighborhood Hits	451	Target Neighborhood Hits	676	Shared Neighborhood Hits	108
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

OGFR_MOUSE
NC score	0.213081 (rank : 50)	θ value	0.00102713 (rank : 44)
Query Neighborhood Hits	451	Target Neighborhood Hits	584	Shared Neighborhood Hits	113
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

WBP11_HUMAN
NC score	0.213053 (rank : 51)	θ value	0.00869519 (rank : 65)
Query Neighborhood Hits	451	Target Neighborhood Hits	354	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

TARA_HUMAN
NC score	0.209212 (rank : 52)	θ value	4.03905 (rank : 346)
Query Neighborhood Hits	451	Target Neighborhood Hits	1626	Shared Neighborhood Hits	211
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

WIRE_HUMAN
NC score	0.208549 (rank : 53)	θ value	0.279714 (rank : 143)
Query Neighborhood Hits	451	Target Neighborhood Hits	329	Shared Neighborhood Hits	84
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

WBP11_MOUSE
NC score	0.206763 (rank : 54)	θ value	0.00869519 (rank : 66)
Query Neighborhood Hits	451	Target Neighborhood Hits	362	Shared Neighborhood Hits	76
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

STRAD_MOUSE
NC score	0.203996 (rank : 55)	θ value	0.21417 (rank : 133)
Query Neighborhood Hits	451	Target Neighborhood Hits	57	Shared Neighborhood Hits	18
SwissProt Accessions	Q60924	Gene names	Stra13
Domain Architecture	No domain graphic available
Description	Retinoic acid-inducible E3 protein (Hematopoietic-specific protein E3).

NFH_MOUSE
NC score	0.203068 (rank : 56)	θ value	0.00020696 (rank : 27)
Query Neighborhood Hits	451	Target Neighborhood Hits	2247	Shared Neighborhood Hits	266
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

BAT2_HUMAN
NC score	0.202755 (rank : 57)	θ value	0.0736092 (rank : 92)
Query Neighborhood Hits	451	Target Neighborhood Hits	931	Shared Neighborhood Hits	180
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

MLL2_HUMAN
NC score	0.202481 (rank : 58)	θ value	4.45536e-07 (rank : 9)
Query Neighborhood Hits	451	Target Neighborhood Hits	1788	Shared Neighborhood Hits	210
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

SF3A2_MOUSE
NC score	0.202401 (rank : 59)	θ value	0.0193708 (rank : 69)
Query Neighborhood Hits	451	Target Neighborhood Hits	247	Shared Neighborhood Hits	62
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

WIRE_MOUSE
NC score	0.200497 (rank : 60)	θ value	0.0431538 (rank : 85)
Query Neighborhood Hits	451	Target Neighborhood Hits	310	Shared Neighborhood Hits	80
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

CABIN_HUMAN
NC score	0.200101 (rank : 61)	θ value	0.00509761 (rank : 55)
Query Neighborhood Hits	451	Target Neighborhood Hits	490	Shared Neighborhood Hits	117
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

DIAP1_MOUSE
NC score	0.200089 (rank : 62)	θ value	2.88788e-06 (rank : 12)
Query Neighborhood Hits	451	Target Neighborhood Hits	839	Shared Neighborhood Hits	87
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

PRP2_MOUSE
NC score	0.199737 (rank : 63)	θ value	1.06291 (rank : 214)
Query Neighborhood Hits	451	Target Neighborhood Hits	347	Shared Neighborhood Hits	77
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

SF3A2_HUMAN
NC score	0.199316 (rank : 64)	θ value	0.0193708 (rank : 68)
Query Neighborhood Hits	451	Target Neighborhood Hits	263	Shared Neighborhood Hits	59
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

MLL3_HUMAN
NC score	0.198636 (rank : 65)	θ value	8.99809 (rank : 429)
Query Neighborhood Hits	451	Target Neighborhood Hits	1644	Shared Neighborhood Hits	254
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

PI5PA_HUMAN
NC score	0.197683 (rank : 66)	θ value	0.00869519 (rank : 62)
Query Neighborhood Hits	451	Target Neighborhood Hits	749	Shared Neighborhood Hits	174
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

BAT2_MOUSE
NC score	0.196984 (rank : 67)	θ value	0.813845 (rank : 183)
Query Neighborhood Hits	451	Target Neighborhood Hits	947	Shared Neighborhood Hits	192
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BCL9_HUMAN
NC score	0.195791 (rank : 68)	θ value	θ > 10 (rank : 494)
Query Neighborhood Hits	451	Target Neighborhood Hits	1008	Shared Neighborhood Hits	205
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

BSN_HUMAN
NC score	0.195476 (rank : 69)	θ value	0.00175202 (rank : 47)
Query Neighborhood Hits	451	Target Neighborhood Hits	1537	Shared Neighborhood Hits	202
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

MAP1A_HUMAN
NC score	0.195018 (rank : 70)	θ value	0.000786445 (rank : 37)
Query Neighborhood Hits	451	Target Neighborhood Hits	1626	Shared Neighborhood Hits	225
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

DIAP1_HUMAN
NC score	0.194649 (rank : 71)	θ value	0.000158464 (rank : 24)
Query Neighborhood Hits	451	Target Neighborhood Hits	784	Shared Neighborhood Hits	92
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

NCOA6_MOUSE
NC score	0.194402 (rank : 72)	θ value	6.88961 (rank : 403)
Query Neighborhood Hits	451	Target Neighborhood Hits	1076	Shared Neighborhood Hits	223
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

TROAP_HUMAN
NC score	0.193773 (rank : 73)	θ value	0.62314 (rank : 179)
Query Neighborhood Hits	451	Target Neighborhood Hits	258	Shared Neighborhood Hits	86
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

SPRR3_HUMAN
NC score	0.192091 (rank : 74)	θ value	θ > 10 (rank : 784)
Query Neighborhood Hits	451	Target Neighborhood Hits	102	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UBC9, O75597, Q4ZGI7, Q5T525, Q8NET7, Q9UDG3	Gene names	SPRR3, SPRC
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta) (Esophagin) (22 kDa pancornulin).

MAP1B_MOUSE
NC score	0.190941 (rank : 75)	θ value	0.00869519 (rank : 59)
Query Neighborhood Hits	451	Target Neighborhood Hits	977	Shared Neighborhood Hits	123
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

BAG3_MOUSE
NC score	0.189182 (rank : 76)	θ value	1.81305 (rank : 245)
Query Neighborhood Hits	451	Target Neighborhood Hits	513	Shared Neighborhood Hits	162
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

MBD6_HUMAN
NC score	0.186748 (rank : 77)	θ value	0.00869519 (rank : 60)
Query Neighborhood Hits	451	Target Neighborhood Hits	349	Shared Neighborhood Hits	74
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

MISS_MOUSE
NC score	0.186664 (rank : 78)	θ value	θ > 10 (rank : 651)
Query Neighborhood Hits	451	Target Neighborhood Hits	444	Shared Neighborhood Hits	138
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

TGON2_HUMAN
NC score	0.186391 (rank : 79)	θ value	θ > 10 (rank : 816)
Query Neighborhood Hits	451	Target Neighborhood Hits	1037	Shared Neighborhood Hits	157
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

PRB4S_HUMAN
NC score	0.186320 (rank : 80)	θ value	0.21417 (rank : 131)
Query Neighborhood Hits	451	Target Neighborhood Hits	330	Shared Neighborhood Hits	74
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

SPR1A_MOUSE
NC score	0.185347 (rank : 81)	θ value	0.365318 (rank : 156)
Query Neighborhood Hits	451	Target Neighborhood Hits	343	Shared Neighborhood Hits	119
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

MINT_MOUSE
NC score	0.184713 (rank : 82)	θ value	5.27518 (rank : 366)
Query Neighborhood Hits	451	Target Neighborhood Hits	1514	Shared Neighborhood Hits	250
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

PRP1_HUMAN
NC score	0.184333 (rank : 83)	θ value	5.27518 (rank : 374)
Query Neighborhood Hits	451	Target Neighborhood Hits	385	Shared Neighborhood Hits	86
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

LAD1_HUMAN
NC score	0.182397 (rank : 84)	θ value	θ > 10 (rank : 625)
Query Neighborhood Hits	451	Target Neighborhood Hits	441	Shared Neighborhood Hits	102
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

MLL3_MOUSE
NC score	0.179768 (rank : 85)	θ value	θ > 10 (rank : 652)
Query Neighborhood Hits	451	Target Neighborhood Hits	1399	Shared Neighborhood Hits	225
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

WASF1_HUMAN
NC score	0.177918 (rank : 86)	θ value	0.0330416 (rank : 79)
Query Neighborhood Hits	451	Target Neighborhood Hits	260	Shared Neighborhood Hits	69
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

CK024_HUMAN
NC score	0.176782 (rank : 87)	θ value	θ > 10 (rank : 522)
Query Neighborhood Hits	451	Target Neighborhood Hits	408	Shared Neighborhood Hits	105
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

RGS3_HUMAN
NC score	0.175852 (rank : 88)	θ value	θ > 10 (rank : 733)
Query Neighborhood Hits	451	Target Neighborhood Hits	1375	Shared Neighborhood Hits	259
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

WASF1_MOUSE
NC score	0.175538 (rank : 89)	θ value	0.0961366 (rank : 101)
Query Neighborhood Hits	451	Target Neighborhood Hits	261	Shared Neighborhood Hits	68
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

MLL4_HUMAN
NC score	0.174877 (rank : 90)	θ value	0.00869519 (rank : 61)
Query Neighborhood Hits	451	Target Neighborhood Hits	722	Shared Neighborhood Hits	137
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

GA2L2_MOUSE
NC score	0.172286 (rank : 91)	θ value	1.06291 (rank : 206)
Query Neighborhood Hits	451	Target Neighborhood Hits	395	Shared Neighborhood Hits	127
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

MUC2_HUMAN
NC score	0.172254 (rank : 92)	θ value	5.81887e-07 (rank : 10)
Query Neighborhood Hits	451	Target Neighborhood Hits	906	Shared Neighborhood Hits	110
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

PSL1_HUMAN
NC score	0.171995 (rank : 93)	θ value	1.38821 (rank : 237)
Query Neighborhood Hits	451	Target Neighborhood Hits	650	Shared Neighborhood Hits	178
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

RIN3_MOUSE
NC score	0.171743 (rank : 94)	θ value	0.000786445 (rank : 39)
Query Neighborhood Hits	451	Target Neighborhood Hits	239	Shared Neighborhood Hits	67
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

YLPM1_HUMAN
NC score	0.171599 (rank : 95)	θ value	8.99809 (rank : 449)
Query Neighborhood Hits	451	Target Neighborhood Hits	670	Shared Neighborhood Hits	135
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

RTP3_MOUSE
NC score	0.171557 (rank : 96)	θ value	θ > 10 (rank : 747)
Query Neighborhood Hits	451	Target Neighborhood Hits	374	Shared Neighborhood Hits	133
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

BRD4_HUMAN
NC score	0.171524 (rank : 97)	θ value	9.29e-05 (rank : 18)
Query Neighborhood Hits	451	Target Neighborhood Hits	851	Shared Neighborhood Hits	134
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

K1802_HUMAN
NC score	0.171148 (rank : 98)	θ value	3.0926 (rank : 300)
Query Neighborhood Hits	451	Target Neighborhood Hits	1378	Shared Neighborhood Hits	204
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

RERE_HUMAN
NC score	0.170732 (rank : 99)	θ value	0.125558 (rank : 110)
Query Neighborhood Hits	451	Target Neighborhood Hits	779	Shared Neighborhood Hits	127
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

SET1A_HUMAN
NC score	0.170255 (rank : 100)	θ value	0.0563607 (rank : 89)
Query Neighborhood Hits	451	Target Neighborhood Hits	690	Shared Neighborhood Hits	104
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

PRB3_HUMAN
NC score	0.170078 (rank : 101)	θ value	0.279714 (rank : 139)
Query Neighborhood Hits	451	Target Neighborhood Hits	318	Shared Neighborhood Hits	78
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

CO039_MOUSE
NC score	0.169551 (rank : 102)	θ value	θ > 10 (rank : 530)
Query Neighborhood Hits	451	Target Neighborhood Hits	445	Shared Neighborhood Hits	145
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

WASP_HUMAN
NC score	0.169271 (rank : 103)	θ value	1.06291 (rank : 223)
Query Neighborhood Hits	451	Target Neighborhood Hits	195	Shared Neighborhood Hits	63
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

MADCA_HUMAN
NC score	0.169025 (rank : 104)	θ value	0.125558 (rank : 105)
Query Neighborhood Hits	451	Target Neighborhood Hits	221	Shared Neighborhood Hits	50
SwissProt Accessions	Q13477, O60222, O75867	Gene names	MADCAM1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (hMAdCAM-1).

WASF2_MOUSE
NC score	0.168506 (rank : 105)	θ value	1.06291 (rank : 221)
Query Neighborhood Hits	451	Target Neighborhood Hits	315	Shared Neighborhood Hits	84
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

NIPBL_HUMAN
NC score	0.168273 (rank : 106)	θ value	0.365318 (rank : 155)
Query Neighborhood Hits	451	Target Neighborhood Hits	1311	Shared Neighborhood Hits	168
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

WASF4_HUMAN
NC score	0.167871 (rank : 107)	θ value	0.279714 (rank : 142)
Query Neighborhood Hits	451	Target Neighborhood Hits	282	Shared Neighborhood Hits	81
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

SYNJ1_HUMAN
NC score	0.167869 (rank : 108)	θ value	0.00298849 (rank : 51)
Query Neighborhood Hits	451	Target Neighborhood Hits	498	Shared Neighborhood Hits	131
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

LR37A_HUMAN
NC score	0.167266 (rank : 109)	θ value	6.88961 (rank : 400)
Query Neighborhood Hits	451	Target Neighborhood Hits	720	Shared Neighborhood Hits	126
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

GGN_MOUSE
NC score	0.166395 (rank : 110)	θ value	0.47712 (rank : 162)
Query Neighborhood Hits	451	Target Neighborhood Hits	311	Shared Neighborhood Hits	69
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

CBP_MOUSE
NC score	0.165841 (rank : 111)	θ value	θ > 10 (rank : 511)
Query Neighborhood Hits	451	Target Neighborhood Hits	1051	Shared Neighborhood Hits	204
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

RERE_MOUSE
NC score	0.165816 (rank : 112)	θ value	0.0961366 (rank : 99)
Query Neighborhood Hits	451	Target Neighborhood Hits	785	Shared Neighborhood Hits	133
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

NOLC1_HUMAN
NC score	0.165782 (rank : 113)	θ value	0.00298849 (rank : 50)
Query Neighborhood Hits	451	Target Neighborhood Hits	452	Shared Neighborhood Hits	64
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

MAP4_HUMAN
NC score	0.165541 (rank : 114)	θ value	0.813845 (rank : 191)
Query Neighborhood Hits	451	Target Neighborhood Hits	428	Shared Neighborhood Hits	94
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

AFF1_HUMAN
NC score	0.164805 (rank : 115)	θ value	0.0961366 (rank : 95)
Query Neighborhood Hits	451	Target Neighborhood Hits	506	Shared Neighborhood Hits	88
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

BRD4_MOUSE
NC score	0.162168 (rank : 116)	θ value	0.000461057 (rank : 32)
Query Neighborhood Hits	451	Target Neighborhood Hits	845	Shared Neighborhood Hits	127
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

DIAP2_MOUSE
NC score	0.162028 (rank : 117)	θ value	0.0961366 (rank : 97)
Query Neighborhood Hits	451	Target Neighborhood Hits	260	Shared Neighborhood Hits	57
SwissProt Accessions	O70566, Q8C2G8	Gene names	Diaph2, Diap2
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2) (mDia3).

GSCR1_HUMAN
NC score	0.161658 (rank : 118)	θ value	2.36792 (rank : 272)
Query Neighborhood Hits	451	Target Neighborhood Hits	674	Shared Neighborhood Hits	131
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

WASF2_HUMAN
NC score	0.161563 (rank : 119)	θ value	0.365318 (rank : 157)
Query Neighborhood Hits	451	Target Neighborhood Hits	280	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

MKL1_MOUSE
NC score	0.161281 (rank : 120)	θ value	0.125558 (rank : 106)
Query Neighborhood Hits	451	Target Neighborhood Hits	667	Shared Neighborhood Hits	171
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

FHOD1_MOUSE
NC score	0.160635 (rank : 121)	θ value	1.81305 (rank : 251)
Query Neighborhood Hits	451	Target Neighborhood Hits	217	Shared Neighborhood Hits	51
SwissProt Accessions	Q6P9Q4, Q8BMK2	Gene names	Fhod1, Fhos1
Domain Architecture	No domain graphic available
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

GGN_HUMAN
NC score	0.159104 (rank : 122)	θ value	0.365318 (rank : 148)
Query Neighborhood Hits	451	Target Neighborhood Hits	269	Shared Neighborhood Hits	70
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

NPBL_MOUSE
NC score	0.157426 (rank : 123)	θ value	θ > 10 (rank : 680)
Query Neighborhood Hits	451	Target Neighborhood Hits	1041	Shared Neighborhood Hits	157
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

FMNL_HUMAN
NC score	0.156545 (rank : 124)	θ value	6.88961 (rank : 393)
Query Neighborhood Hits	451	Target Neighborhood Hits	529	Shared Neighborhood Hits	86
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

K1543_HUMAN
NC score	0.156076 (rank : 125)	θ value	0.62314 (rank : 173)
Query Neighborhood Hits	451	Target Neighborhood Hits	435	Shared Neighborhood Hits	130
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

K1543_MOUSE
NC score	0.154696 (rank : 126)	θ value	4.03905 (rank : 333)
Query Neighborhood Hits	451	Target Neighborhood Hits	497	Shared Neighborhood Hits	135
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

AB1IP_MOUSE
NC score	0.154411 (rank : 127)	θ value	0.0330416 (rank : 71)
Query Neighborhood Hits	451	Target Neighborhood Hits	181	Shared Neighborhood Hits	59
SwissProt Accessions	Q8R5A3, O35329, Q8BRU0, Q99KV8	Gene names	Apbb1ip, Prel1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 48).

LPP_HUMAN
NC score	0.153397 (rank : 128)	θ value	θ > 10 (rank : 631)
Query Neighborhood Hits	451	Target Neighborhood Hits	775	Shared Neighborhood Hits	188
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

PS1C2_HUMAN
NC score	0.152789 (rank : 129)	θ value	3.0926 (rank : 310)
Query Neighborhood Hits	451	Target Neighborhood Hits	66	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UIG4	Gene names	PSORS1C2, C6orf17, SPR1
Domain Architecture	No domain graphic available
Description	Psoriasis susceptibility 1 candidate gene 2 protein precursor (SPR1 protein).

AFF1_MOUSE
NC score	0.151672 (rank : 130)	θ value	0.00390308 (rank : 52)
Query Neighborhood Hits	451	Target Neighborhood Hits	351	Shared Neighborhood Hits	65
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

CBP_HUMAN
NC score	0.150726 (rank : 131)	θ value	θ > 10 (rank : 510)
Query Neighborhood Hits	451	Target Neighborhood Hits	941	Shared Neighborhood Hits	175
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

SYNJ1_MOUSE
NC score	0.150578 (rank : 132)	θ value	1.06291 (rank : 218)
Query Neighborhood Hits	451	Target Neighborhood Hits	516	Shared Neighborhood Hits	144
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

EP300_HUMAN
NC score	0.149834 (rank : 133)	θ value	0.365318 (rank : 147)
Query Neighborhood Hits	451	Target Neighborhood Hits	821	Shared Neighborhood Hits	143
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

CCNK_MOUSE
NC score	0.148864 (rank : 134)	θ value	0.00665767 (rank : 57)
Query Neighborhood Hits	451	Target Neighborhood Hits	350	Shared Neighborhood Hits	80
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

BCL9_MOUSE
NC score	0.148825 (rank : 135)	θ value	θ > 10 (rank : 495)
Query Neighborhood Hits	451	Target Neighborhood Hits	770	Shared Neighborhood Hits	170
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

GAK4_HUMAN
NC score	0.148707 (rank : 136)	θ value	0.21417 (rank : 128)
Query Neighborhood Hits	451	Target Neighborhood Hits	415	Shared Neighborhood Hits	149
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK11_HUMAN
NC score	0.148242 (rank : 137)	θ value	0.21417 (rank : 125)
Query Neighborhood Hits	451	Target Neighborhood Hits	409	Shared Neighborhood Hits	149
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

CIC_HUMAN
NC score	0.148224 (rank : 138)	θ value	6.88961 (rank : 389)
Query Neighborhood Hits	451	Target Neighborhood Hits	992	Shared Neighborhood Hits	186
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

GAK5_HUMAN
NC score	0.148219 (rank : 139)	θ value	1.06291 (rank : 207)
Query Neighborhood Hits	451	Target Neighborhood Hits	429	Shared Neighborhood Hits	154
SwissProt Accessions	P62684	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K113 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

DGKK_HUMAN
NC score	0.147730 (rank : 140)	θ value	0.00102713 (rank : 42)
Query Neighborhood Hits	451	Target Neighborhood Hits	378	Shared Neighborhood Hits	59
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

WASP_MOUSE
NC score	0.147484 (rank : 141)	θ value	3.0926 (rank : 325)
Query Neighborhood Hits	451	Target Neighborhood Hits	223	Shared Neighborhood Hits	63
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

GAK2_HUMAN
NC score	0.147155 (rank : 142)	θ value	0.21417 (rank : 127)
Query Neighborhood Hits	451	Target Neighborhood Hits	406	Shared Neighborhood Hits	148
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

SAPS1_HUMAN
NC score	0.146606 (rank : 143)	θ value	θ > 10 (rank : 750)
Query Neighborhood Hits	451	Target Neighborhood Hits	704	Shared Neighborhood Hits	166
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

GAK6_HUMAN
NC score	0.146161 (rank : 144)	θ value	0.21417 (rank : 129)
Query Neighborhood Hits	451	Target Neighborhood Hits	392	Shared Neighborhood Hits	142
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

NCOR2_HUMAN
NC score	0.146156 (rank : 145)	θ value	0.0563607 (rank : 88)
Query Neighborhood Hits	451	Target Neighborhood Hits	870	Shared Neighborhood Hits	136
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

CIZ1_HUMAN
NC score	0.145596 (rank : 146)	θ value	8.99809 (rank : 413)
Query Neighborhood Hits	451	Target Neighborhood Hits	359	Shared Neighborhood Hits	86
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

SMR1_MOUSE
NC score	0.145545 (rank : 147)	θ value	2.36792 (rank : 282)
Query Neighborhood Hits	451	Target Neighborhood Hits	103	Shared Neighborhood Hits	41
SwissProt Accessions	Q61900	Gene names	Smr1, Msg1
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 1 precursor (Salivary protein MSG1).

MBB1A_HUMAN
NC score	0.145522 (rank : 148)	θ value	θ > 10 (rank : 640)
Query Neighborhood Hits	451	Target Neighborhood Hits	665	Shared Neighborhood Hits	131
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

DIAP2_HUMAN
NC score	0.145461 (rank : 149)	θ value	1.38821 (rank : 231)
Query Neighborhood Hits	451	Target Neighborhood Hits	342	Shared Neighborhood Hits	50
SwissProt Accessions	O60879, O60878, Q8WX06, Q8WX48, Q9UJL2	Gene names	DIAPH2, DIA
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2).

MUCDL_HUMAN
NC score	0.145446 (rank : 150)	θ value	θ > 10 (rank : 659)
Query Neighborhood Hits	451	Target Neighborhood Hits	777	Shared Neighborhood Hits	149
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

K1683_HUMAN
NC score	0.144816 (rank : 151)	θ value	θ > 10 (rank : 623)
Query Neighborhood Hits	451	Target Neighborhood Hits	240	Shared Neighborhood Hits	71
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

DIDO1_HUMAN
NC score	0.144773 (rank : 152)	θ value	5.27518 (rank : 357)
Query Neighborhood Hits	451	Target Neighborhood Hits	960	Shared Neighborhood Hits	155
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

YLPM1_MOUSE
NC score	0.142591 (rank : 153)	θ value	0.47712 (rank : 170)
Query Neighborhood Hits	451	Target Neighborhood Hits	505	Shared Neighborhood Hits	88
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

SNPC4_HUMAN
NC score	0.142476 (rank : 154)	θ value	θ > 10 (rank : 777)
Query Neighborhood Hits	451	Target Neighborhood Hits	589	Shared Neighborhood Hits	146
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

PRAX_HUMAN
NC score	0.141639 (rank : 155)	θ value	θ > 10 (rank : 711)
Query Neighborhood Hits	451	Target Neighborhood Hits	215	Shared Neighborhood Hits	54
SwissProt Accessions	Q9BXM0, Q9BXL9, Q9HCF2	Gene names	PRX, KIAA1620
Domain Architecture
Description	Periaxin.

TARA_MOUSE
NC score	0.141318 (rank : 156)	θ value	0.279714 (rank : 141)
Query Neighborhood Hits	451	Target Neighborhood Hits	1133	Shared Neighborhood Hits	150
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

GAK12_HUMAN
NC score	0.140429 (rank : 157)	θ value	0.21417 (rank : 126)
Query Neighborhood Hits	451	Target Neighborhood Hits	374	Shared Neighborhood Hits	144
SwissProt Accessions	P63130, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K102 Gag protein) (HERV-K(III) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

WASF3_HUMAN
NC score	0.139606 (rank : 158)	θ value	1.06291 (rank : 222)
Query Neighborhood Hits	451	Target Neighborhood Hits	204	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UPY6, O94974	Gene names	WASF3, KIAA0900, SCAR3, WAVE3
Domain Architecture
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3) (Verprolin homology domain-containing protein 3).

TULP4_HUMAN
NC score	0.139273 (rank : 159)	θ value	0.47712 (rank : 168)
Query Neighborhood Hits	451	Target Neighborhood Hits	426	Shared Neighborhood Hits	124
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

KI67_HUMAN
NC score	0.139141 (rank : 160)	θ value	θ > 10 (rank : 624)
Query Neighborhood Hits	451	Target Neighborhood Hits	581	Shared Neighborhood Hits	92
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

RIN3_HUMAN
NC score	0.138385 (rank : 161)	θ value	0.21417 (rank : 132)
Query Neighborhood Hits	451	Target Neighborhood Hits	227	Shared Neighborhood Hits	67
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

TAF4_HUMAN
NC score	0.138346 (rank : 162)	θ value	θ > 10 (rank : 804)
Query Neighborhood Hits	451	Target Neighborhood Hits	687	Shared Neighborhood Hits	102
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

PELP1_MOUSE
NC score	0.137518 (rank : 163)	θ value	θ > 10 (rank : 696)
Query Neighborhood Hits	451	Target Neighborhood Hits	709	Shared Neighborhood Hits	114
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

MNT_HUMAN
NC score	0.136595 (rank : 164)	θ value	θ > 10 (rank : 653)
Query Neighborhood Hits	451	Target Neighborhood Hits	496	Shared Neighborhood Hits	123
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

LIPS_HUMAN
NC score	0.135537 (rank : 165)	θ value	0.163984 (rank : 115)
Query Neighborhood Hits	451	Target Neighborhood Hits	314	Shared Neighborhood Hits	85
SwissProt Accessions	Q05469, Q3LRT2, Q6NSL7	Gene names	LIPE
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

TP53B_MOUSE
NC score	0.135187 (rank : 166)	θ value	θ > 10 (rank : 822)
Query Neighborhood Hits	451	Target Neighborhood Hits	644	Shared Neighborhood Hits	119
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

AFF4_HUMAN
NC score	0.134470 (rank : 167)	θ value	0.0736092 (rank : 91)
Query Neighborhood Hits	451	Target Neighborhood Hits	611	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

SC24C_HUMAN
NC score	0.134428 (rank : 168)	θ value	θ > 10 (rank : 753)
Query Neighborhood Hits	451	Target Neighborhood Hits	662	Shared Neighborhood Hits	156
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

AMELX_HUMAN
NC score	0.134002 (rank : 169)	θ value	0.0961366 (rank : 96)
Query Neighborhood Hits	451	Target Neighborhood Hits	95	Shared Neighborhood Hits	31
SwissProt Accessions	Q99217, Q96NW6, Q9UCA7	Gene names	AMELX, AMG, AMGX
Domain Architecture
Description	Amelogenin, X isoform precursor.

TPO_MOUSE
NC score	0.133068 (rank : 170)	θ value	θ > 10 (rank : 823)
Query Neighborhood Hits	451	Target Neighborhood Hits	258	Shared Neighborhood Hits	104
SwissProt Accessions	P40226	Gene names	Thpo
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

SFPQ_MOUSE
NC score	0.132791 (rank : 171)	θ value	0.125558 (rank : 111)
Query Neighborhood Hits	451	Target Neighborhood Hits	958	Shared Neighborhood Hits	111
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

FMNL_MOUSE
NC score	0.132597 (rank : 172)	θ value	4.03905 (rank : 331)
Query Neighborhood Hits	451	Target Neighborhood Hits	428	Shared Neighborhood Hits	71
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

SSBP4_HUMAN
NC score	0.132534 (rank : 173)	θ value	θ > 10 (rank : 789)
Query Neighborhood Hits	451	Target Neighborhood Hits	753	Shared Neighborhood Hits	161
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

MAP4_MOUSE
NC score	0.131991 (rank : 174)	θ value	θ > 10 (rank : 635)
Query Neighborhood Hits	451	Target Neighborhood Hits	409	Shared Neighborhood Hits	82
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

GAK10_HUMAN
NC score	0.131095 (rank : 175)	θ value	0.279714 (rank : 136)
Query Neighborhood Hits	451	Target Neighborhood Hits	289	Shared Neighborhood Hits	108
SwissProt Accessions	P87889, P10263, P10264, Q69385, Q9UKH6	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q33.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K10 Gag protein) (HERV-K107 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

PRAX_MOUSE
NC score	0.130741 (rank : 176)	θ value	θ > 10 (rank : 712)
Query Neighborhood Hits	451	Target Neighborhood Hits	199	Shared Neighborhood Hits	49
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

AB1IP_HUMAN
NC score	0.129591 (rank : 177)	θ value	1.81305 (rank : 243)
Query Neighborhood Hits	451	Target Neighborhood Hits	213	Shared Neighborhood Hits	51
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

MINT_HUMAN
NC score	0.129540 (rank : 178)	θ value	θ > 10 (rank : 650)
Query Neighborhood Hits	451	Target Neighborhood Hits	1291	Shared Neighborhood Hits	184
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

SFRIP_HUMAN
NC score	0.129422 (rank : 179)	θ value	θ > 10 (rank : 769)
Query Neighborhood Hits	451	Target Neighborhood Hits	530	Shared Neighborhood Hits	91
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

TXND2_MOUSE
NC score	0.129301 (rank : 180)	θ value	θ > 10 (rank : 827)
Query Neighborhood Hits	451	Target Neighborhood Hits	828	Shared Neighborhood Hits	92
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

MTSS1_MOUSE
NC score	0.128943 (rank : 181)	θ value	θ > 10 (rank : 655)
Query Neighborhood Hits	451	Target Neighborhood Hits	592	Shared Neighborhood Hits	140
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

CECR2_HUMAN
NC score	0.128884 (rank : 182)	θ value	θ > 10 (rank : 516)
Query Neighborhood Hits	451	Target Neighborhood Hits	543	Shared Neighborhood Hits	126
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

ENAH_MOUSE
NC score	0.128527 (rank : 183)	θ value	0.365318 (rank : 146)
Query Neighborhood Hits	451	Target Neighborhood Hits	919	Shared Neighborhood Hits	118
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

WASF3_MOUSE
NC score	0.127681 (rank : 184)	θ value	1.81305 (rank : 262)
Query Neighborhood Hits	451	Target Neighborhood Hits	188	Shared Neighborhood Hits	53
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

FHOD1_HUMAN
NC score	0.127344 (rank : 185)	θ value	θ > 10 (rank : 575)
Query Neighborhood Hits	451	Target Neighborhood Hits	184	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Y613, Q59F76, Q6Y1F2, Q76MS8, Q8N521	Gene names	FHOD1, FHOS
Domain Architecture
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

CJ108_HUMAN
NC score	0.126011 (rank : 186)	θ value	5.27518 (rank : 353)
Query Neighborhood Hits	451	Target Neighborhood Hits	165	Shared Neighborhood Hits	71
SwissProt Accessions	Q8N8Z3	Gene names	C10orf108
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C10orf108.

T22D4_HUMAN
NC score	0.125767 (rank : 187)	θ value	θ > 10 (rank : 798)
Query Neighborhood Hits	451	Target Neighborhood Hits	403	Shared Neighborhood Hits	108
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

SPRR3_MOUSE
NC score	0.124962 (rank : 188)	θ value	θ > 10 (rank : 785)
Query Neighborhood Hits	451	Target Neighborhood Hits	106	Shared Neighborhood Hits	34
SwissProt Accessions	O09116	Gene names	Sprr3
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta).

MUC5B_HUMAN
NC score	0.124940 (rank : 189)	θ value	0.00228821 (rank : 49)
Query Neighborhood Hits	451	Target Neighborhood Hits	1020	Shared Neighborhood Hits	88
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

ARI1A_HUMAN
NC score	0.124766 (rank : 190)	θ value	1.81305 (rank : 244)
Query Neighborhood Hits	451	Target Neighborhood Hits	787	Shared Neighborhood Hits	144
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

AFF2_MOUSE
NC score	0.124717 (rank : 191)	θ value	2.36792 (rank : 266)
Query Neighborhood Hits	451	Target Neighborhood Hits	225	Shared Neighborhood Hits	78
SwissProt Accessions	O55112	Gene names	Aff2, Fmr2, Ox19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation protein 2 homolog) (Protein FMR-2) (FMR2P) (Protein Ox19).

CJ012_HUMAN
NC score	0.124546 (rank : 192)	θ value	θ > 10 (rank : 521)
Query Neighborhood Hits	451	Target Neighborhood Hits	467	Shared Neighborhood Hits	86
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

IF4G1_MOUSE
NC score	0.124376 (rank : 193)	θ value	θ > 10 (rank : 609)
Query Neighborhood Hits	451	Target Neighborhood Hits	534	Shared Neighborhood Hits	141
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

CS016_HUMAN
NC score	0.123662 (rank : 194)	θ value	θ > 10 (rank : 538)
Query Neighborhood Hits	451	Target Neighborhood Hits	310	Shared Neighborhood Hits	72
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

AMELY_HUMAN
NC score	0.122791 (rank : 195)	θ value	0.0252991 (rank : 70)
Query Neighborhood Hits	451	Target Neighborhood Hits	57	Shared Neighborhood Hits	18
SwissProt Accessions	Q99218, Q6RWT1	Gene names	AMELY, AMGL, AMGY
Domain Architecture
Description	Amelogenin, Y isoform precursor.

AFF4_MOUSE
NC score	0.122710 (rank : 196)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	451	Target Neighborhood Hits	581	Shared Neighborhood Hits	92
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

ZIMP7_MOUSE
NC score	0.122618 (rank : 197)	θ value	θ > 10 (rank : 846)
Query Neighborhood Hits	451	Target Neighborhood Hits	566	Shared Neighborhood Hits	128
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

BAG3_HUMAN
NC score	0.122435 (rank : 198)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	451	Target Neighborhood Hits	314	Shared Neighborhood Hits	85
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

GAK1_HUMAN
NC score	0.122192 (rank : 199)	θ value	0.163984 (rank : 114)
Query Neighborhood Hits	451	Target Neighborhood Hits	268	Shared Neighborhood Hits	100
SwissProt Accessions	P62683	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_12q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

PRR8_HUMAN
NC score	0.121850 (rank : 200)	θ value	1.81305 (rank : 258)
Query Neighborhood Hits	451	Target Neighborhood Hits	217	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NSV0	Gene names	PRR8
Domain Architecture	No domain graphic available
Description	Proline-rich protein 8.

ANK2_HUMAN
NC score	0.121378 (rank : 201)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	451	Target Neighborhood Hits	1615	Shared Neighborhood Hits	247
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

BCAR1_HUMAN
NC score	0.121318 (rank : 202)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	451	Target Neighborhood Hits	554	Shared Neighborhood Hits	138
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

CSKI1_MOUSE
NC score	0.121022 (rank : 203)	θ value	0.00228821 (rank : 48)
Query Neighborhood Hits	451	Target Neighborhood Hits	1031	Shared Neighborhood Hits	185
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

ATX2_MOUSE
NC score	0.120522 (rank : 204)	θ value	1.06291 (rank : 199)
Query Neighborhood Hits	451	Target Neighborhood Hits	445	Shared Neighborhood Hits	99
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

BASP_HUMAN
NC score	0.120436 (rank : 205)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	451	Target Neighborhood Hits	321	Shared Neighborhood Hits	50
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

GRIN1_HUMAN
NC score	0.120413 (rank : 206)	θ value	θ > 10 (rank : 598)
Query Neighborhood Hits	451	Target Neighborhood Hits	681	Shared Neighborhood Hits	101
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

MILK1_MOUSE
NC score	0.120406 (rank : 207)	θ value	θ > 10 (rank : 648)
Query Neighborhood Hits	451	Target Neighborhood Hits	788	Shared Neighborhood Hits	177
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

NUMBL_HUMAN
NC score	0.120226 (rank : 208)	θ value	θ > 10 (rank : 686)
Query Neighborhood Hits	451	Target Neighborhood Hits	394	Shared Neighborhood Hits	119
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

FYB_HUMAN
NC score	0.119903 (rank : 209)	θ value	θ > 10 (rank : 577)
Query Neighborhood Hits	451	Target Neighborhood Hits	379	Shared Neighborhood Hits	101
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

AFF2_HUMAN
NC score	0.119673 (rank : 210)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	451	Target Neighborhood Hits	218	Shared Neighborhood Hits	67
SwissProt Accessions	P51816, O43786, O60215, P78407, Q13521, Q14323, Q9UNA5	Gene names	AFF2, FMR2, OX19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation 2 protein) (Protein FMR-2) (FMR2P) (Protein Ox19) (Fragile X E mental retardation syndrome protein).

HRX_HUMAN
NC score	0.119350 (rank : 211)	θ value	8.99809 (rank : 425)
Query Neighborhood Hits	451	Target Neighborhood Hits	825	Shared Neighborhood Hits	124
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

AUTS2_HUMAN
NC score	0.118622 (rank : 212)	θ value	1.06291 (rank : 200)
Query Neighborhood Hits	451	Target Neighborhood Hits	342	Shared Neighborhood Hits	86
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

NCOR2_MOUSE
NC score	0.117574 (rank : 213)	θ value	1.38821 (rank : 235)
Query Neighborhood Hits	451	Target Neighborhood Hits	790	Shared Neighborhood Hits	115
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

PELP1_HUMAN
NC score	0.116605 (rank : 214)	θ value	1.38821 (rank : 236)
Query Neighborhood Hits	451	Target Neighborhood Hits	596	Shared Neighborhood Hits	71
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

TAU_MOUSE
NC score	0.116295 (rank : 215)	θ value	θ > 10 (rank : 806)
Query Neighborhood Hits	451	Target Neighborhood Hits	502	Shared Neighborhood Hits	114
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

ATX7_HUMAN
NC score	0.116098 (rank : 216)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	451	Target Neighborhood Hits	351	Shared Neighborhood Hits	122
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

PDZD2_HUMAN
NC score	0.115960 (rank : 217)	θ value	0.163984 (rank : 116)
Query Neighborhood Hits	451	Target Neighborhood Hits	772	Shared Neighborhood Hits	111
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

DIAP3_MOUSE
NC score	0.114557 (rank : 218)	θ value	θ > 10 (rank : 552)
Query Neighborhood Hits	451	Target Neighborhood Hits	221	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Z207	Gene names	Diaph3, Diap3
Domain Architecture
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3) (mDIA2) (p134mDIA2).

WBS14_HUMAN
NC score	0.114550 (rank : 219)	θ value	0.47712 (rank : 169)
Query Neighborhood Hits	451	Target Neighborhood Hits	273	Shared Neighborhood Hits	55
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

VCXC_HUMAN
NC score	0.114393 (rank : 220)	θ value	θ > 10 (rank : 834)
Query Neighborhood Hits	451	Target Neighborhood Hits	139	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H321	Gene names	VCXC
Domain Architecture	No domain graphic available
Description	VCX-C protein (Variably charged protein X-C).

PRCC_HUMAN
NC score	0.114386 (rank : 221)	θ value	0.813845 (rank : 195)
Query Neighborhood Hits	451	Target Neighborhood Hits	109	Shared Neighborhood Hits	35
SwissProt Accessions	Q92733, O00665, O00724	Gene names	PRCC, TPRC
Domain Architecture	No domain graphic available
Description	Proline-rich protein PRCC (Papillary renal cell carcinoma translocation-associated gene protein).

RBBP6_MOUSE
NC score	0.114273 (rank : 222)	θ value	θ > 10 (rank : 727)
Query Neighborhood Hits	451	Target Neighborhood Hits	1014	Shared Neighborhood Hits	113
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

ZN750_MOUSE
NC score	0.113814 (rank : 223)	θ value	θ > 10 (rank : 851)
Query Neighborhood Hits	451	Target Neighborhood Hits	346	Shared Neighborhood Hits	84
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

ZN385_HUMAN
NC score	0.113419 (rank : 224)	θ value	θ > 10 (rank : 849)
Query Neighborhood Hits	451	Target Neighborhood Hits	614	Shared Neighborhood Hits	127
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

CRTC1_HUMAN
NC score	0.113108 (rank : 225)	θ value	3.0926 (rank : 293)
Query Neighborhood Hits	451	Target Neighborhood Hits	319	Shared Neighborhood Hits	97
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

ENL_HUMAN
NC score	0.112849 (rank : 226)	θ value	0.813845 (rank : 188)
Query Neighborhood Hits	451	Target Neighborhood Hits	305	Shared Neighborhood Hits	49
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

K0310_HUMAN
NC score	0.111525 (rank : 227)	θ value	θ > 10 (rank : 621)
Query Neighborhood Hits	451	Target Neighborhood Hits	420	Shared Neighborhood Hits	104
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

CSKI1_HUMAN
NC score	0.110992 (rank : 228)	θ value	9.29e-05 (rank : 19)
Query Neighborhood Hits	451	Target Neighborhood Hits	997	Shared Neighborhood Hits	148
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

IF4G1_HUMAN
NC score	0.110502 (rank : 229)	θ value	0.00035302 (rank : 31)
Query Neighborhood Hits	451	Target Neighborhood Hits	347	Shared Neighborhood Hits	69
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

GRIN1_MOUSE
NC score	0.110417 (rank : 230)	θ value	θ > 10 (rank : 599)
Query Neighborhood Hits	451	Target Neighborhood Hits	337	Shared Neighborhood Hits	87
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

RL1D1_HUMAN
NC score	0.110286 (rank : 231)	θ value	3.0926 (rank : 312)
Query Neighborhood Hits	451	Target Neighborhood Hits	180	Shared Neighborhood Hits	45
SwissProt Accessions	O76021, Q6PL22, Q8IWS7, Q8WUZ1, Q9HDA9, Q9Y3Z9	Gene names	RSL1D1, CATX11, CSIG, PBK1
Domain Architecture	No domain graphic available
Description	Ribosomal L1 domain-containing protein 1 (Cellular senescence- inhibited gene protein) (Protein PBK1) (CATX-11).

SPT5H_MOUSE
NC score	0.110230 (rank : 232)	θ value	θ > 10 (rank : 787)
Query Neighborhood Hits	451	Target Neighborhood Hits	437	Shared Neighborhood Hits	98
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

3BP2_HUMAN
NC score	0.110098 (rank : 233)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	451	Target Neighborhood Hits	296	Shared Neighborhood Hits	93
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

TCGAP_HUMAN
NC score	0.110054 (rank : 234)	θ value	θ > 10 (rank : 810)
Query Neighborhood Hits	451	Target Neighborhood Hits	872	Shared Neighborhood Hits	169
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

NU214_HUMAN
NC score	0.109961 (rank : 235)	θ value	2.36792 (rank : 280)
Query Neighborhood Hits	451	Target Neighborhood Hits	657	Shared Neighborhood Hits	82
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

PI5PA_MOUSE
NC score	0.109894 (rank : 236)	θ value	1.81305 (rank : 255)
Query Neighborhood Hits	451	Target Neighborhood Hits	331	Shared Neighborhood Hits	80
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

RBBP6_HUMAN
NC score	0.109367 (rank : 237)	θ value	θ > 10 (rank : 726)
Query Neighborhood Hits	451	Target Neighborhood Hits	1135	Shared Neighborhood Hits	118
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

SFPQ_HUMAN
NC score	0.109322 (rank : 238)	θ value	3.0926 (rank : 314)
Query Neighborhood Hits	451	Target Neighborhood Hits	986	Shared Neighborhood Hits	115
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

GAK3_HUMAN
NC score	0.109296 (rank : 239)	θ value	0.0431538 (rank : 82)
Query Neighborhood Hits	451	Target Neighborhood Hits	182	Shared Neighborhood Hits	66
SwissProt Accessions	Q9YNA8	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19q12 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(C19) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

VCX3_HUMAN
NC score	0.109215 (rank : 240)	θ value	θ > 10 (rank : 833)
Query Neighborhood Hits	451	Target Neighborhood Hits	105	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NNX9, Q9P0H4	Gene names	VCX3A, VCX3, VCX8R, VCXA
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 3 (VCX-A protein) (Variably charged protein X-A) (Variable charge protein on X with eight repeats) (VCX- 8r).

TAU_HUMAN
NC score	0.108832 (rank : 241)	θ value	θ > 10 (rank : 805)
Query Neighborhood Hits	451	Target Neighborhood Hits	448	Shared Neighborhood Hits	111
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

ZN645_HUMAN
NC score	0.108814 (rank : 242)	θ value	θ > 10 (rank : 850)
Query Neighborhood Hits	451	Target Neighborhood Hits	265	Shared Neighborhood Hits	89
SwissProt Accessions	Q8N7E2, Q6DJY9	Gene names	ZNF645
Domain Architecture	No domain graphic available
Description	Zinc finger protein 645.

SEPT9_HUMAN
NC score	0.108519 (rank : 243)	θ value	θ > 10 (rank : 758)
Query Neighborhood Hits	451	Target Neighborhood Hits	706	Shared Neighborhood Hits	166
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

BLNK_MOUSE
NC score	0.108371 (rank : 244)	θ value	θ > 10 (rank : 499)
Query Neighborhood Hits	451	Target Neighborhood Hits	296	Shared Neighborhood Hits	92
SwissProt Accessions	Q9QUN3, O88504	Gene names	Blnk, Bash, Ly57, Slp65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65) (Lymphocyte antigen 57).

LRC56_HUMAN
NC score	0.108361 (rank : 245)	θ value	0.365318 (rank : 153)
Query Neighborhood Hits	451	Target Neighborhood Hits	165	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IYG6, Q8N3Q4	Gene names	LRRC56
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 56.

ATX7_MOUSE
NC score	0.108277 (rank : 246)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	451	Target Neighborhood Hits	328	Shared Neighborhood Hits	111
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

GTSE1_HUMAN
NC score	0.108129 (rank : 247)	θ value	θ > 10 (rank : 600)
Query Neighborhood Hits	451	Target Neighborhood Hits	193	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NYZ3, Q53GX5, Q5R3I6, Q6DHX4, Q9BRE0, Q9UGZ9, Q9Y557	Gene names	GTSE1
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (B99 homolog).

CSF1_HUMAN
NC score	0.107658 (rank : 248)	θ value	θ > 10 (rank : 539)
Query Neighborhood Hits	451	Target Neighborhood Hits	258	Shared Neighborhood Hits	78
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

SPT5H_HUMAN
NC score	0.107188 (rank : 249)	θ value	θ > 10 (rank : 786)
Query Neighborhood Hits	451	Target Neighborhood Hits	436	Shared Neighborhood Hits	96
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

SFR11_HUMAN
NC score	0.106837 (rank : 250)	θ value	3.0926 (rank : 315)
Query Neighborhood Hits	451	Target Neighborhood Hits	246	Shared Neighborhood Hits	38
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

CD248_HUMAN
NC score	0.106233 (rank : 251)	θ value	θ > 10 (rank : 513)
Query Neighborhood Hits	451	Target Neighborhood Hits	679	Shared Neighborhood Hits	135
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CI079_HUMAN
NC score	0.105695 (rank : 252)	θ value	θ > 10 (rank : 519)
Query Neighborhood Hits	451	Target Neighborhood Hits	288	Shared Neighborhood Hits	69
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

VCY1_HUMAN
NC score	0.105421 (rank : 253)	θ value	5.27518 (rank : 381)
Query Neighborhood Hits	451	Target Neighborhood Hits	38	Shared Neighborhood Hits	9
SwissProt Accessions	O14598	Gene names	VCY, BPY1
Domain Architecture	No domain graphic available
Description	Testis-specific basic protein Y 1 (Variably charged protein Y).

DIAP3_HUMAN
NC score	0.105345 (rank : 254)	θ value	θ > 10 (rank : 551)
Query Neighborhood Hits	451	Target Neighborhood Hits	209	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NSV4, Q5T2S7, Q5XKF6, Q6MZF0, Q6NUP0, Q86VS4, Q8NAV4	Gene names	DIAPH3, DIAP3
Domain Architecture	No domain graphic available
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3).

IASPP_MOUSE
NC score	0.104799 (rank : 255)	θ value	θ > 10 (rank : 604)
Query Neighborhood Hits	451	Target Neighborhood Hits	1024	Shared Neighborhood Hits	167
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

SMOO_HUMAN
NC score	0.104692 (rank : 256)	θ value	0.125558 (rank : 112)
Query Neighborhood Hits	451	Target Neighborhood Hits	391	Shared Neighborhood Hits	73
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

NRX2B_HUMAN
NC score	0.104657 (rank : 257)	θ value	θ > 10 (rank : 682)
Query Neighborhood Hits	451	Target Neighborhood Hits	481	Shared Neighborhood Hits	125
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

MTSS1_HUMAN
NC score	0.104290 (rank : 258)	θ value	θ > 10 (rank : 654)
Query Neighborhood Hits	451	Target Neighborhood Hits	504	Shared Neighborhood Hits	102
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

ACINU_HUMAN
NC score	0.104152 (rank : 259)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	451	Target Neighborhood Hits	828	Shared Neighborhood Hits	93
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

TM108_MOUSE
NC score	0.103764 (rank : 260)	θ value	θ > 10 (rank : 819)
Query Neighborhood Hits	451	Target Neighborhood Hits	336	Shared Neighborhood Hits	83
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

ASPP1_MOUSE
NC score	0.103605 (rank : 261)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	451	Target Neighborhood Hits	1244	Shared Neighborhood Hits	169
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

JADE2_MOUSE
NC score	0.103571 (rank : 262)	θ value	θ > 10 (rank : 616)
Query Neighborhood Hits	451	Target Neighborhood Hits	560	Shared Neighborhood Hits	148
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

DAAM1_MOUSE
NC score	0.103466 (rank : 263)	θ value	1.38821 (rank : 230)
Query Neighborhood Hits	451	Target Neighborhood Hits	443	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BPM0, Q80Y68, Q9CQQ2	Gene names	Daam1
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

DAAM1_HUMAN
NC score	0.103437 (rank : 264)	θ value	8.99809 (rank : 415)
Query Neighborhood Hits	451	Target Neighborhood Hits	483	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y4D1, Q86U34, Q8N1Z8, Q8TB39	Gene names	DAAM1, KIAA0666
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

CPSF6_MOUSE
NC score	0.103242 (rank : 265)	θ value	θ > 10 (rank : 533)
Query Neighborhood Hits	451	Target Neighborhood Hits	356	Shared Neighborhood Hits	74
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

BAZ2A_MOUSE
NC score	0.102905 (rank : 266)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	451	Target Neighborhood Hits	744	Shared Neighborhood Hits	148
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

LARP4_MOUSE
NC score	0.102688 (rank : 267)	θ value	θ > 10 (rank : 626)
Query Neighborhood Hits	451	Target Neighborhood Hits	260	Shared Neighborhood Hits	84
SwissProt Accessions	Q8BWW4, Q3UR69	Gene names	Larp4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

TCOF_MOUSE
NC score	0.102119 (rank : 268)	θ value	θ > 10 (rank : 812)
Query Neighborhood Hits	451	Target Neighborhood Hits	471	Shared Neighborhood Hits	71
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

SC24A_MOUSE
NC score	0.101849 (rank : 269)	θ value	θ > 10 (rank : 752)
Query Neighborhood Hits	451	Target Neighborhood Hits	394	Shared Neighborhood Hits	134
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

CPSF6_HUMAN
NC score	0.101486 (rank : 270)	θ value	θ > 10 (rank : 532)
Query Neighborhood Hits	451	Target Neighborhood Hits	359	Shared Neighborhood Hits	73
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

CO039_HUMAN
NC score	0.101205 (rank : 271)	θ value	0.813845 (rank : 186)
Query Neighborhood Hits	451	Target Neighborhood Hits	264	Shared Neighborhood Hits	73
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

ALEX_MOUSE
NC score	0.100657 (rank : 272)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	451	Target Neighborhood Hits	197	Shared Neighborhood Hits	57
SwissProt Accessions	Q6R0H6, Q8BIR3	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

RIMS1_HUMAN
NC score	0.100627 (rank : 273)	θ value	0.0330416 (rank : 77)
Query Neighborhood Hits	451	Target Neighborhood Hits	437	Shared Neighborhood Hits	50
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

TCOF_HUMAN
NC score	0.100220 (rank : 274)	θ value	θ > 10 (rank : 811)
Query Neighborhood Hits	451	Target Neighborhood Hits	543	Shared Neighborhood Hits	76
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

BASP_MOUSE
NC score	0.100044 (rank : 275)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	451	Target Neighborhood Hits	260	Shared Neighborhood Hits	35
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

MNT_MOUSE
NC score	0.099846 (rank : 276)	θ value	2.36792 (rank : 277)
Query Neighborhood Hits	451	Target Neighborhood Hits	432	Shared Neighborhood Hits	80
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

ZIM10_HUMAN
NC score	0.099428 (rank : 277)	θ value	2.36792 (rank : 288)
Query Neighborhood Hits	451	Target Neighborhood Hits	577	Shared Neighborhood Hits	130
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

CK024_MOUSE
NC score	0.099067 (rank : 278)	θ value	θ > 10 (rank : 523)
Query Neighborhood Hits	451	Target Neighborhood Hits	307	Shared Neighborhood Hits	55
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

ATX2L_HUMAN
NC score	0.098994 (rank : 279)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	451	Target Neighborhood Hits	443	Shared Neighborhood Hits	94
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

PHLB1_HUMAN
NC score	0.098932 (rank : 280)	θ value	0.813845 (rank : 194)
Query Neighborhood Hits	451	Target Neighborhood Hits	1038	Shared Neighborhood Hits	131
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

JPH2_HUMAN
NC score	0.098821 (rank : 281)	θ value	θ > 10 (rank : 620)
Query Neighborhood Hits	451	Target Neighborhood Hits	639	Shared Neighborhood Hits	159
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

SFR15_HUMAN
NC score	0.098429 (rank : 282)	θ value	θ > 10 (rank : 768)
Query Neighborhood Hits	451	Target Neighborhood Hits	368	Shared Neighborhood Hits	77
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

DAAM2_MOUSE
NC score	0.098411 (rank : 283)	θ value	θ > 10 (rank : 546)
Query Neighborhood Hits	451	Target Neighborhood Hits	371	Shared Neighborhood Hits	44
SwissProt Accessions	Q80U19, Q810J5	Gene names	Daam2, Kiaa0381
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 2.

TRDN_HUMAN
NC score	0.098015 (rank : 284)	θ value	1.06291 (rank : 219)
Query Neighborhood Hits	451	Target Neighborhood Hits	542	Shared Neighborhood Hits	51
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

VCX1_HUMAN
NC score	0.098009 (rank : 285)	θ value	θ > 10 (rank : 831)
Query Neighborhood Hits	451	Target Neighborhood Hits	129	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H320, Q9P0H3	Gene names	VCX, VCX1, VCX10R, VCXB1
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 1 (VCX-B1 protein) (Variably charged protein X-B1) (Variable charge protein on X with ten repeats) (VCX- 10r).

SF3A1_MOUSE
NC score	0.097890 (rank : 286)	θ value	5.27518 (rank : 375)
Query Neighborhood Hits	451	Target Neighborhood Hits	198	Shared Neighborhood Hits	43
SwissProt Accessions	Q8K4Z5, Q8C0M7, Q8C128, Q8C175, Q921T3	Gene names	Sf3a1
Domain Architecture	No domain graphic available
Description	Splicing factor 3 subunit 1 (SF3a120).

PHC2_HUMAN
NC score	0.097691 (rank : 287)	θ value	θ > 10 (rank : 700)
Query Neighborhood Hits	451	Target Neighborhood Hits	388	Shared Neighborhood Hits	107
SwissProt Accessions	Q8IXK0, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7	Gene names	PHC2, EDR2, PH2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2).

RBM12_HUMAN
NC score	0.097462 (rank : 288)	θ value	0.279714 (rank : 140)
Query Neighborhood Hits	451	Target Neighborhood Hits	298	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NTZ6, O94865, Q8N3B1, Q9H196	Gene names	RBM12, KIAA0765
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

CG1_HUMAN
NC score	0.097373 (rank : 289)	θ value	θ > 10 (rank : 518)
Query Neighborhood Hits	451	Target Neighborhood Hits	222	Shared Neighborhood Hits	62
SwissProt Accessions	Q13495	Gene names	CXorf6, CG1
Domain Architecture	No domain graphic available
Description	CG1 protein (F18).

OBF1_HUMAN
NC score	0.097071 (rank : 290)	θ value	θ > 10 (rank : 688)
Query Neighborhood Hits	451	Target Neighborhood Hits	203	Shared Neighborhood Hits	74
SwissProt Accessions	Q16633, Q14983	Gene names	POU2AF1, OBF1
Domain Architecture	No domain graphic available
Description	POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (OCT-binding factor 1) (BOB-1) (OCA-B).

ATX2_HUMAN
NC score	0.097010 (rank : 291)	θ value	1.06291 (rank : 198)
Query Neighborhood Hits	451	Target Neighborhood Hits	375	Shared Neighborhood Hits	75
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

CIC_MOUSE
NC score	0.096971 (rank : 292)	θ value	θ > 10 (rank : 520)
Query Neighborhood Hits	451	Target Neighborhood Hits	742	Shared Neighborhood Hits	131
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

SF3A1_HUMAN
NC score	0.096532 (rank : 293)	θ value	θ > 10 (rank : 765)
Query Neighborhood Hits	451	Target Neighborhood Hits	199	Shared Neighborhood Hits	46
SwissProt Accessions	Q15459	Gene names	SF3A1, SAP114
Domain Architecture
Description	Splicing factor 3 subunit 1 (Spliceosome-associated protein 114) (SAP 114) (SF3a120).

MUC1_MOUSE
NC score	0.096474 (rank : 294)	θ value	θ > 10 (rank : 658)
Query Neighborhood Hits	451	Target Neighborhood Hits	388	Shared Neighborhood Hits	58
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

LRC56_MOUSE
NC score	0.096247 (rank : 295)	θ value	0.0563607 (rank : 87)
Query Neighborhood Hits	451	Target Neighborhood Hits	100	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K375, Q571F2	Gene names	Lrrc56
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 56.

MYO15_HUMAN
NC score	0.096103 (rank : 296)	θ value	0.000786445 (rank : 38)
Query Neighborhood Hits	451	Target Neighborhood Hits	671	Shared Neighborhood Hits	181
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

SOX13_HUMAN
NC score	0.095972 (rank : 297)	θ value	θ > 10 (rank : 778)
Query Neighborhood Hits	451	Target Neighborhood Hits	464	Shared Neighborhood Hits	134
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

PHAR2_HUMAN
NC score	0.095814 (rank : 298)	θ value	0.813845 (rank : 193)
Query Neighborhood Hits	451	Target Neighborhood Hits	208	Shared Neighborhood Hits	36
SwissProt Accessions	O75167, Q68DM2	Gene names	PHACTR2, C6orf56, KIAA0680
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 2.

SPR1A_HUMAN
NC score	0.095696 (rank : 299)	θ value	2.36792 (rank : 285)
Query Neighborhood Hits	451	Target Neighborhood Hits	136	Shared Neighborhood Hits	41
SwissProt Accessions	P35321, Q9UDG4	Gene names	SPRR1A
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein IA) (SPR-IA) (SPRK) (19 kDa pancornulin).

MAGC1_HUMAN
NC score	0.095347 (rank : 300)	θ value	9.29e-05 (rank : 20)
Query Neighborhood Hits	451	Target Neighborhood Hits	431	Shared Neighborhood Hits	81
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

SYN1_HUMAN
NC score	0.095183 (rank : 301)	θ value	2.36792 (rank : 286)
Query Neighborhood Hits	451	Target Neighborhood Hits	419	Shared Neighborhood Hits	87
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

TRI66_MOUSE
NC score	0.094617 (rank : 302)	θ value	1.06291 (rank : 220)
Query Neighborhood Hits	451	Target Neighborhood Hits	491	Shared Neighborhood Hits	95
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

GNAS1_MOUSE
NC score	0.094595 (rank : 303)	θ value	θ > 10 (rank : 592)
Query Neighborhood Hits	451	Target Neighborhood Hits	651	Shared Neighborhood Hits	139
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

BAT3_MOUSE
NC score	0.093994 (rank : 304)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	451	Target Neighborhood Hits	518	Shared Neighborhood Hits	111
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

BRD8_MOUSE
NC score	0.093845 (rank : 305)	θ value	θ > 10 (rank : 504)
Query Neighborhood Hits	451	Target Neighborhood Hits	422	Shared Neighborhood Hits	63
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

ARI1B_HUMAN
NC score	0.093821 (rank : 306)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	451	Target Neighborhood Hits	567	Shared Neighborhood Hits	120
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

CO002_HUMAN
NC score	0.093537 (rank : 307)	θ value	θ > 10 (rank : 529)
Query Neighborhood Hits	451	Target Neighborhood Hits	387	Shared Neighborhood Hits	73
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

RBM12_MOUSE
NC score	0.093445 (rank : 308)	θ value	3.0926 (rank : 311)
Query Neighborhood Hits	451	Target Neighborhood Hits	313	Shared Neighborhood Hits	50
SwissProt Accessions	Q8R4X3, Q8K373, Q8R302, Q9CS80	Gene names	Rbm12
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

DAAM2_HUMAN
NC score	0.093291 (rank : 309)	θ value	θ > 10 (rank : 545)
Query Neighborhood Hits	451	Target Neighborhood Hits	350	Shared Neighborhood Hits	37
SwissProt Accessions	Q86T65, Q5T4U0, Q9NQI5, Q9Y4G0	Gene names	DAAM2, KIAA0381
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 2.

NFH_HUMAN
NC score	0.093250 (rank : 310)	θ value	0.000602161 (rank : 36)
Query Neighborhood Hits	451	Target Neighborhood Hits	1242	Shared Neighborhood Hits	110
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

TTC16_HUMAN
NC score	0.093180 (rank : 311)	θ value	8.99809 (rank : 445)
Query Neighborhood Hits	451	Target Neighborhood Hits	417	Shared Neighborhood Hits	64
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

PHF20_MOUSE
NC score	0.093027 (rank : 312)	θ value	θ > 10 (rank : 701)
Query Neighborhood Hits	451	Target Neighborhood Hits	513	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

ATX2L_MOUSE
NC score	0.092237 (rank : 313)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	451	Target Neighborhood Hits	401	Shared Neighborhood Hits	87
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

CARD6_HUMAN
NC score	0.091948 (rank : 314)	θ value	0.125558 (rank : 102)
Query Neighborhood Hits	451	Target Neighborhood Hits	145	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BX69	Gene names	CARD6
Domain Architecture
Description	Caspase recruitment domain-containing protein 6.

CASC3_MOUSE
NC score	0.091622 (rank : 315)	θ value	θ > 10 (rank : 508)
Query Neighborhood Hits	451	Target Neighborhood Hits	333	Shared Neighborhood Hits	80
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

TAF3_HUMAN
NC score	0.091509 (rank : 316)	θ value	0.0961366 (rank : 100)
Query Neighborhood Hits	451	Target Neighborhood Hits	568	Shared Neighborhood Hits	63
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

AL2S4_MOUSE
NC score	0.091481 (rank : 317)	θ value	8.99809 (rank : 410)
Query Neighborhood Hits	451	Target Neighborhood Hits	193	Shared Neighborhood Hits	62
SwissProt Accessions	Q3V0J1, Q3TIS2	Gene names	Als2cr4
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein homolog.

ZN207_HUMAN
NC score	0.091469 (rank : 318)	θ value	θ > 10 (rank : 847)
Query Neighborhood Hits	451	Target Neighborhood Hits	326	Shared Neighborhood Hits	53
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

NCOR1_HUMAN
NC score	0.091400 (rank : 319)	θ value	θ > 10 (rank : 667)
Query Neighborhood Hits	451	Target Neighborhood Hits	577	Shared Neighborhood Hits	85
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

BCAR1_MOUSE
NC score	0.091328 (rank : 320)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	451	Target Neighborhood Hits	438	Shared Neighborhood Hits	114
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

CTDP1_HUMAN
NC score	0.090884 (rank : 321)	θ value	θ > 10 (rank : 544)
Query Neighborhood Hits	451	Target Neighborhood Hits	416	Shared Neighborhood Hits	98
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

ATX1_MOUSE
NC score	0.090706 (rank : 322)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	451	Target Neighborhood Hits	264	Shared Neighborhood Hits	83
SwissProt Accessions	P54254	Gene names	Atxn1, Sca1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).

ENAM_MOUSE
NC score	0.090697 (rank : 323)	θ value	θ > 10 (rank : 569)
Query Neighborhood Hits	451	Target Neighborhood Hits	229	Shared Neighborhood Hits	64
SwissProt Accessions	O55196	Gene names	Enam
Domain Architecture	No domain graphic available
Description	Enamelin precursor.

PKCB1_HUMAN
NC score	0.090644 (rank : 324)	θ value	1.06291 (rank : 212)
Query Neighborhood Hits	451	Target Neighborhood Hits	488	Shared Neighborhood Hits	68
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

GAK8_HUMAN
NC score	0.090082 (rank : 325)	θ value	θ > 10 (rank : 590)
Query Neighborhood Hits	451	Target Neighborhood Hits	145	Shared Neighborhood Hits	54
SwissProt Accessions	Q9HDB9	Gene names	ERVK5
Domain Architecture	No domain graphic available
Description	HERV-K_3q12.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(II) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

RIMS2_HUMAN
NC score	0.089609 (rank : 326)	θ value	0.00509761 (rank : 56)
Query Neighborhood Hits	451	Target Neighborhood Hits	342	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

CD248_MOUSE
NC score	0.089060 (rank : 327)	θ value	θ > 10 (rank : 514)
Query Neighborhood Hits	451	Target Neighborhood Hits	578	Shared Neighborhood Hits	128
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

SELV_HUMAN
NC score	0.089005 (rank : 328)	θ value	θ > 10 (rank : 757)
Query Neighborhood Hits	451	Target Neighborhood Hits	118	Shared Neighborhood Hits	28
SwissProt Accessions	P59797	Gene names	SELV
Domain Architecture	No domain graphic available
Description	Selenoprotein V.

PKHA4_HUMAN
NC score	0.088986 (rank : 329)	θ value	0.163984 (rank : 117)
Query Neighborhood Hits	451	Target Neighborhood Hits	283	Shared Neighborhood Hits	52
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

LEUK_HUMAN
NC score	0.088695 (rank : 330)	θ value	θ > 10 (rank : 629)
Query Neighborhood Hits	451	Target Neighborhood Hits	213	Shared Neighborhood Hits	39
SwissProt Accessions	P16150	Gene names	SPN, CD43
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Galactoglycoprotein) (GALGP) (CD43 antigen).

ESX1L_HUMAN
NC score	0.088642 (rank : 331)	θ value	4.1701e-05 (rank : 15)
Query Neighborhood Hits	451	Target Neighborhood Hits	498	Shared Neighborhood Hits	52
SwissProt Accessions	Q8N693, Q7Z6K7	Gene names	ESX1L, ESX1R
Domain Architecture
Description	Extraembryonic, spermatogenesis, homeobox 1-like protein.

K0460_MOUSE
NC score	0.088509 (rank : 332)	θ value	3.0926 (rank : 299)
Query Neighborhood Hits	451	Target Neighborhood Hits	374	Shared Neighborhood Hits	59
SwissProt Accessions	Q6NXI6, Q3U3L8, Q6ZQA7	Gene names	Kiaa0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

GAK18_HUMAN
NC score	0.088502 (rank : 333)	θ value	θ > 10 (rank : 587)
Query Neighborhood Hits	451	Target Neighborhood Hits	116	Shared Neighborhood Hits	46
SwissProt Accessions	P62690	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.23 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

CT151_HUMAN
NC score	0.088227 (rank : 334)	θ value	θ > 10 (rank : 542)
Query Neighborhood Hits	451	Target Neighborhood Hits	382	Shared Neighborhood Hits	63
SwissProt Accessions	Q8NC74, Q8N4Z9, Q9BR75, Q9H0Y9	Gene names	C20orf151
Domain Architecture
Description	Uncharacterized protein C20orf151.

NFRKB_MOUSE
NC score	0.087925 (rank : 335)	θ value	θ > 10 (rank : 675)
Query Neighborhood Hits	451	Target Neighborhood Hits	393	Shared Neighborhood Hits	97
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

PRP5_HUMAN
NC score	0.087393 (rank : 336)	θ value	θ > 10 (rank : 714)
Query Neighborhood Hits	451	Target Neighborhood Hits	108	Shared Neighborhood Hits	31
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

CN032_MOUSE
NC score	0.087384 (rank : 337)	θ value	θ > 10 (rank : 525)
Query Neighborhood Hits	451	Target Neighborhood Hits	233	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

PER3_HUMAN
NC score	0.087373 (rank : 338)	θ value	θ > 10 (rank : 698)
Query Neighborhood Hits	451	Target Neighborhood Hits	479	Shared Neighborhood Hits	113
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

SETBP_MOUSE
NC score	0.087303 (rank : 339)	θ value	θ > 10 (rank : 760)
Query Neighborhood Hits	451	Target Neighborhood Hits	352	Shared Neighborhood Hits	86
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

CRSP2_HUMAN
NC score	0.086879 (rank : 340)	θ value	θ > 10 (rank : 534)
Query Neighborhood Hits	451	Target Neighborhood Hits	380	Shared Neighborhood Hits	88
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

GAK7_HUMAN
NC score	0.086352 (rank : 341)	θ value	θ > 10 (rank : 589)
Query Neighborhood Hits	451	Target Neighborhood Hits	90	Shared Neighborhood Hits	37
SwissProt Accessions	Q96PI4, Q9QC08	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q23.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K18 Gag protein) (HERV-K110 Gag protein) (HERV-K(C1a) Gag protein) [Contains: Matrix protein].

AKA12_HUMAN
NC score	0.086302 (rank : 342)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	451	Target Neighborhood Hits	825	Shared Neighborhood Hits	76
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

RIMS2_MOUSE
NC score	0.086299 (rank : 343)	θ value	0.163984 (rank : 118)
Query Neighborhood Hits	451	Target Neighborhood Hits	376	Shared Neighborhood Hits	34
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

DCP1A_HUMAN
NC score	0.086168 (rank : 344)	θ value	θ > 10 (rank : 550)
Query Neighborhood Hits	451	Target Neighborhood Hits	228	Shared Neighborhood Hits	68
SwissProt Accessions	Q9NPI6	Gene names	DCP1A, SMIF
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (Smad4-interacting transcriptional co-activator).

K1210_HUMAN
NC score	0.085822 (rank : 345)	θ value	θ > 10 (rank : 622)
Query Neighborhood Hits	451	Target Neighborhood Hits	219	Shared Neighborhood Hits	54
SwissProt Accessions	Q9ULL0, Q5JPN4	Gene names	KIAA1210
Domain Architecture	No domain graphic available
Description	Protein KIAA1210.

RP1L1_HUMAN
NC score	0.085543 (rank : 346)	θ value	θ > 10 (rank : 738)
Query Neighborhood Hits	451	Target Neighborhood Hits	1072	Shared Neighborhood Hits	122
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

VCX2_HUMAN
NC score	0.085087 (rank : 347)	θ value	θ > 10 (rank : 832)
Query Neighborhood Hits	451	Target Neighborhood Hits	38	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H322, Q9P0H5	Gene names	VCX2, VCX2R, VCXB
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 2 (VCX-B protein) (Variably charged protein X-B) (Variable charge protein on X with two repeats) (VCX-2r).

TTF1_MOUSE
NC score	0.084922 (rank : 348)	θ value	1.81305 (rank : 261)
Query Neighborhood Hits	451	Target Neighborhood Hits	277	Shared Neighborhood Hits	53
SwissProt Accessions	Q62187, Q9JKK5	Gene names	Ttf1
Domain Architecture	No domain graphic available
Description	Transcription termination factor 1 (TTF-1) (TTF-I) (mTFF-I) (RNA polymerase I termination factor).

GON4L_MOUSE
NC score	0.084574 (rank : 349)	θ value	θ > 10 (rank : 594)
Query Neighborhood Hits	451	Target Neighborhood Hits	455	Shared Neighborhood Hits	86
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

REXO1_MOUSE
NC score	0.084297 (rank : 350)	θ value	0.0330416 (rank : 76)
Query Neighborhood Hits	451	Target Neighborhood Hits	166	Shared Neighborhood Hits	41
SwissProt Accessions	Q7TT28, Q3UMP1, Q69ZR0, Q6NSQ6, Q6PI95, Q9DA29	Gene names	Rexo1, Kiaa1138, Tceb3bp1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Transcription elongation factor B polypeptide 3-binding protein 1).

NSD1_MOUSE
NC score	0.084290 (rank : 351)	θ value	8.99809 (rank : 433)
Query Neighborhood Hits	451	Target Neighborhood Hits	472	Shared Neighborhood Hits	79
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

BAT3_HUMAN
NC score	0.084159 (rank : 352)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	451	Target Neighborhood Hits	490	Shared Neighborhood Hits	107
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

BAZ2A_HUMAN
NC score	0.083723 (rank : 353)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	451	Target Neighborhood Hits	780	Shared Neighborhood Hits	137
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

CS007_MOUSE
NC score	0.082734 (rank : 354)	θ value	θ > 10 (rank : 537)
Query Neighborhood Hits	451	Target Neighborhood Hits	464	Shared Neighborhood Hits	85
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

DMRTD_HUMAN
NC score	0.082515 (rank : 355)	θ value	8.99809 (rank : 417)
Query Neighborhood Hits	451	Target Neighborhood Hits	216	Shared Neighborhood Hits	83
SwissProt Accessions	Q8IXT2, Q8N6Q2, Q96M39, Q96SD4	Gene names	DMRTC2
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2.

PRPC_HUMAN
NC score	0.082508 (rank : 356)	θ value	θ > 10 (rank : 715)
Query Neighborhood Hits	451	Target Neighborhood Hits	165	Shared Neighborhood Hits	34
SwissProt Accessions	P02810, Q4VBP2, Q53XA2, Q6P2F6	Gene names	PRH1
Domain Architecture	No domain graphic available
Description	Salivary acidic proline-rich phosphoprotein 1/2 precursor (PRP-1/PRP- 2) (Parotid proline-rich protein 1/2) (Pr1/Pr2) (Protein C) (Parotid acidic protein) (Pa) (Parotid isoelectric focusing variant protein) (PIF-S) (Parotid double-band protein) (Db-s) [Contains: Salivary acidic proline-rich phosphoprotein 1/2; Salivary acidic proline-rich phosphoprotein 3/4 (PRP-3/PRP-4) (Protein A) (PIF-F) (Db-F); Peptide P-C].

TRI66_HUMAN
NC score	0.082249 (rank : 357)	θ value	1.81305 (rank : 260)
Query Neighborhood Hits	451	Target Neighborhood Hits	479	Shared Neighborhood Hits	92
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

IF4B_MOUSE
NC score	0.081782 (rank : 358)	θ value	θ > 10 (rank : 608)
Query Neighborhood Hits	451	Target Neighborhood Hits	368	Shared Neighborhood Hits	93
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

PHF20_HUMAN
NC score	0.081705 (rank : 359)	θ value	1.06291 (rank : 211)
Query Neighborhood Hits	451	Target Neighborhood Hits	394	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

PRR13_HUMAN
NC score	0.081389 (rank : 360)	θ value	θ > 10 (rank : 717)
Query Neighborhood Hits	451	Target Neighborhood Hits	105	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

NCOR1_MOUSE
NC score	0.081245 (rank : 361)	θ value	θ > 10 (rank : 668)
Query Neighborhood Hits	451	Target Neighborhood Hits	521	Shared Neighborhood Hits	78
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

K0460_HUMAN
NC score	0.081178 (rank : 362)	θ value	6.88961 (rank : 399)
Query Neighborhood Hits	451	Target Neighborhood Hits	357	Shared Neighborhood Hits	56
SwissProt Accessions	Q5VT52, O75048, Q5VT53, Q6MZL4, Q86XD2	Gene names	KIAA0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

ZCPW1_MOUSE
NC score	0.081009 (rank : 363)	θ value	θ > 10 (rank : 845)
Query Neighborhood Hits	451	Target Neighborhood Hits	307	Shared Neighborhood Hits	55
SwissProt Accessions	Q6IR42	Gene names	Zcwpw1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1 homolog.

RSF1_HUMAN
NC score	0.080999 (rank : 364)	θ value	θ > 10 (rank : 744)
Query Neighborhood Hits	451	Target Neighborhood Hits	539	Shared Neighborhood Hits	63
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

GPTC8_HUMAN
NC score	0.080991 (rank : 365)	θ value	θ > 10 (rank : 597)
Query Neighborhood Hits	451	Target Neighborhood Hits	366	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

SFR12_MOUSE
NC score	0.080682 (rank : 366)	θ value	0.62314 (rank : 176)
Query Neighborhood Hits	451	Target Neighborhood Hits	486	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

ANTR1_HUMAN
NC score	0.080476 (rank : 367)	θ value	0.62314 (rank : 171)
Query Neighborhood Hits	451	Target Neighborhood Hits	128	Shared Neighborhood Hits	43
SwissProt Accessions	Q9H6X2, Q96P02, Q9NVP3	Gene names	ANTXR1, ATR, TEM8
Domain Architecture
Description	Anthrax toxin receptor 1 precursor (Tumor endothelial marker 8).

SETBP_HUMAN
NC score	0.080246 (rank : 368)	θ value	θ > 10 (rank : 759)
Query Neighborhood Hits	451	Target Neighborhood Hits	305	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y6X0, Q9UEF3	Gene names	SETBP1, KIAA0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

ADDB_MOUSE
NC score	0.080111 (rank : 369)	θ value	1.38821 (rank : 225)
Query Neighborhood Hits	451	Target Neighborhood Hits	574	Shared Neighborhood Hits	86
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

TMAP1_HUMAN
NC score	0.080014 (rank : 370)	θ value	θ > 10 (rank : 820)
Query Neighborhood Hits	451	Target Neighborhood Hits	140	Shared Neighborhood Hits	27
SwissProt Accessions	P84157	Gene names	TMAP1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

PPRB_MOUSE
NC score	0.079665 (rank : 371)	θ value	3.0926 (rank : 309)
Query Neighborhood Hits	451	Target Neighborhood Hits	354	Shared Neighborhood Hits	68
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

MEGF9_MOUSE
NC score	0.079366 (rank : 372)	θ value	θ > 10 (rank : 646)
Query Neighborhood Hits	451	Target Neighborhood Hits	896	Shared Neighborhood Hits	141
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

WDR46_MOUSE
NC score	0.079140 (rank : 373)	θ value	θ > 10 (rank : 836)
Query Neighborhood Hits	451	Target Neighborhood Hits	243	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Z0H1	Gene names	Wdr46, Bing4
Domain Architecture
Description	WD repeat protein 46 (WD repeat protein BING4).

PER2_MOUSE
NC score	0.078556 (rank : 374)	θ value	θ > 10 (rank : 697)
Query Neighborhood Hits	451	Target Neighborhood Hits	325	Shared Neighborhood Hits	91
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

RTN4_MOUSE
NC score	0.078515 (rank : 375)	θ value	θ > 10 (rank : 746)
Query Neighborhood Hits	451	Target Neighborhood Hits	341	Shared Neighborhood Hits	69
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

INP5E_HUMAN
NC score	0.078514 (rank : 376)	θ value	θ > 10 (rank : 613)
Query Neighborhood Hits	451	Target Neighborhood Hits	201	Shared Neighborhood Hits	68
SwissProt Accessions	Q9NRR6, Q15734	Gene names	INPP5E
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

MYST3_MOUSE
NC score	0.078304 (rank : 377)	θ value	4.03905 (rank : 337)
Query Neighborhood Hits	451	Target Neighborhood Hits	688	Shared Neighborhood Hits	94
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

SASH1_MOUSE
NC score	0.078211 (rank : 378)	θ value	θ > 10 (rank : 751)
Query Neighborhood Hits	451	Target Neighborhood Hits	263	Shared Neighborhood Hits	62
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

CN032_HUMAN
NC score	0.077852 (rank : 379)	θ value	θ > 10 (rank : 524)
Query Neighborhood Hits	451	Target Neighborhood Hits	267	Shared Neighborhood Hits	54
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

APXL_HUMAN
NC score	0.077846 (rank : 380)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	451	Target Neighborhood Hits	553	Shared Neighborhood Hits	88
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

GNAS3_MOUSE
NC score	0.077819 (rank : 381)	θ value	8.99809 (rank : 423)
Query Neighborhood Hits	451	Target Neighborhood Hits	84	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z0F1, Q9QXW5, Q9Z0H2	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Neuroendocrine secretory protein 55 (NESP55) [Contains: LHAL tetrapeptide; GPIPIRRH peptide].

SMR3A_HUMAN
NC score	0.077754 (rank : 382)	θ value	θ > 10 (rank : 774)
Query Neighborhood Hits	451	Target Neighborhood Hits	93	Shared Neighborhood Hits	35
SwissProt Accessions	Q99954	Gene names	SMR3A, PBI, PROL5
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog A precursor (Proline-rich protein 5) (Proline-rich protein PBI).

SGIP1_MOUSE
NC score	0.077752 (rank : 383)	θ value	θ > 10 (rank : 772)
Query Neighborhood Hits	451	Target Neighborhood Hits	180	Shared Neighborhood Hits	40
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

YTDC1_HUMAN
NC score	0.077710 (rank : 384)	θ value	θ > 10 (rank : 838)
Query Neighborhood Hits	451	Target Neighborhood Hits	458	Shared Neighborhood Hits	46
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

MARCS_HUMAN
NC score	0.077666 (rank : 385)	θ value	θ > 10 (rank : 636)
Query Neighborhood Hits	451	Target Neighborhood Hits	204	Shared Neighborhood Hits	38
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

CA106_HUMAN
NC score	0.077638 (rank : 386)	θ value	0.279714 (rank : 135)
Query Neighborhood Hits	451	Target Neighborhood Hits	124	Shared Neighborhood Hits	26
SwissProt Accessions	Q3KP66, Q9NV65, Q9NVI0	Gene names	C1orf106
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106.

GAB1_HUMAN
NC score	0.077533 (rank : 387)	θ value	θ > 10 (rank : 581)
Query Neighborhood Hits	451	Target Neighborhood Hits	279	Shared Neighborhood Hits	99
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

CRTC1_MOUSE
NC score	0.077482 (rank : 388)	θ value	8.99809 (rank : 414)
Query Neighborhood Hits	451	Target Neighborhood Hits	230	Shared Neighborhood Hits	62
SwissProt Accessions	Q68ED7, Q6ZQ85	Gene names	Crtc1, Kiaa0616, Mect1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1 homolog).

DOT1L_HUMAN
NC score	0.077433 (rank : 389)	θ value	θ > 10 (rank : 558)
Query Neighborhood Hits	451	Target Neighborhood Hits	660	Shared Neighborhood Hits	91
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

MBB1A_MOUSE
NC score	0.077382 (rank : 390)	θ value	3.0926 (rank : 303)
Query Neighborhood Hits	451	Target Neighborhood Hits	233	Shared Neighborhood Hits	46
SwissProt Accessions	Q7TPV4, O35851, Q80Y66, Q8R4X2, Q99KP0	Gene names	Mybbp1a, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A (Myb-binding protein of 160 kDa).

IF4B_HUMAN
NC score	0.077332 (rank : 391)	θ value	θ > 10 (rank : 607)
Query Neighborhood Hits	451	Target Neighborhood Hits	417	Shared Neighborhood Hits	86
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

SYN1_MOUSE
NC score	0.077304 (rank : 392)	θ value	θ > 10 (rank : 791)
Query Neighborhood Hits	451	Target Neighborhood Hits	363	Shared Neighborhood Hits	77
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

SYNJ2_HUMAN
NC score	0.077111 (rank : 393)	θ value	θ > 10 (rank : 792)
Query Neighborhood Hits	451	Target Neighborhood Hits	136	Shared Neighborhood Hits	40
SwissProt Accessions	O15056, Q5TA13, Q5TA16, Q5TA19, Q86XK0, Q8IZA8, Q9H226	Gene names	SYNJ2, KIAA0348
Domain Architecture	No domain graphic available
Description	Synaptojanin-2 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 2).

G3BP_HUMAN
NC score	0.076393 (rank : 394)	θ value	0.163984 (rank : 113)
Query Neighborhood Hits	451	Target Neighborhood Hits	219	Shared Neighborhood Hits	25
SwissProt Accessions	Q13283	Gene names	G3BP, G3BP1
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 1 (EC 3.6.1.-) (ATP- dependent DNA helicase VIII) (GAP SH3-domain-binding protein 1) (G3BP- 1) (HDH-VIII).

SOX13_MOUSE
NC score	0.076375 (rank : 395)	θ value	θ > 10 (rank : 779)
Query Neighborhood Hits	451	Target Neighborhood Hits	495	Shared Neighborhood Hits	130
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

MAVS_HUMAN
NC score	0.076340 (rank : 396)	θ value	θ > 10 (rank : 638)
Query Neighborhood Hits	451	Target Neighborhood Hits	271	Shared Neighborhood Hits	62
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

PO121_HUMAN
NC score	0.076223 (rank : 397)	θ value	θ > 10 (rank : 706)
Query Neighborhood Hits	451	Target Neighborhood Hits	344	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

ELOA1_HUMAN
NC score	0.076055 (rank : 398)	θ value	θ > 10 (rank : 564)
Query Neighborhood Hits	451	Target Neighborhood Hits	388	Shared Neighborhood Hits	62
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

SYNPO_HUMAN
NC score	0.076025 (rank : 399)	θ value	θ > 10 (rank : 794)
Query Neighborhood Hits	451	Target Neighborhood Hits	281	Shared Neighborhood Hits	75
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

GTSE1_MOUSE
NC score	0.075677 (rank : 400)	θ value	θ > 10 (rank : 601)
Query Neighborhood Hits	451	Target Neighborhood Hits	245	Shared Neighborhood Hits	59
SwissProt Accessions	Q8R080, O89015, Q9CSG9	Gene names	Gtse1, B99
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (Gtse-1) (B99 protein).

DNMT1_HUMAN
NC score	0.075596 (rank : 401)	θ value	θ > 10 (rank : 556)
Query Neighborhood Hits	451	Target Neighborhood Hits	401	Shared Neighborhood Hits	55
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

NUCKS_HUMAN
NC score	0.075567 (rank : 402)	θ value	θ > 10 (rank : 684)
Query Neighborhood Hits	451	Target Neighborhood Hits	143	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H1E3, Q9H1D6, Q9H723	Gene names	NUCKS1, NUCKS
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (P1).

SYNPO_MOUSE
NC score	0.075435 (rank : 403)	θ value	θ > 10 (rank : 795)
Query Neighborhood Hits	451	Target Neighborhood Hits	242	Shared Neighborhood Hits	64
SwissProt Accessions	Q8CC35, Q99JI0	Gene names	Synpo, Kiaa1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

ZC313_HUMAN
NC score	0.075117 (rank : 404)	θ value	θ > 10 (rank : 842)
Query Neighborhood Hits	451	Target Neighborhood Hits	772	Shared Neighborhood Hits	76
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

RTN4_HUMAN
NC score	0.075081 (rank : 405)	θ value	θ > 10 (rank : 745)
Query Neighborhood Hits	451	Target Neighborhood Hits	357	Shared Neighborhood Hits	81
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

T22D2_HUMAN
NC score	0.075054 (rank : 406)	θ value	θ > 10 (rank : 797)
Query Neighborhood Hits	451	Target Neighborhood Hits	250	Shared Neighborhood Hits	55
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

SPR2H_MOUSE
NC score	0.075003 (rank : 407)	θ value	θ > 10 (rank : 783)
Query Neighborhood Hits	451	Target Neighborhood Hits	82	Shared Neighborhood Hits	23
SwissProt Accessions	O70559	Gene names	Sprr2h
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2H.

CPSF7_HUMAN
NC score	0.074756 (rank : 408)	θ value	1.38821 (rank : 228)
Query Neighborhood Hits	451	Target Neighborhood Hits	125	Shared Neighborhood Hits	30
SwissProt Accessions	Q8N684, Q7Z3H9, Q9H025, Q9H9V1	Gene names	CPSF7
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 7 (Cleavage and polyadenylation specificity factor 59 kDa subunit) (CPSF 59 kDa subunit) (Pre-mRNA cleavage factor Im 59 kDa subunit).

GON4L_HUMAN
NC score	0.074680 (rank : 409)	θ value	6.88961 (rank : 395)
Query Neighborhood Hits	451	Target Neighborhood Hits	555	Shared Neighborhood Hits	88
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

CPSF7_MOUSE
NC score	0.074625 (rank : 410)	θ value	1.38821 (rank : 229)
Query Neighborhood Hits	451	Target Neighborhood Hits	123	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BTV2, Q3TNF1, Q8BKE7, Q8CFS8	Gene names	Cpsf7
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 7.

SVIL_MOUSE
NC score	0.074541 (rank : 411)	θ value	θ > 10 (rank : 790)
Query Neighborhood Hits	451	Target Neighborhood Hits	439	Shared Neighborhood Hits	82
SwissProt Accessions	Q8K4L3	Gene names	Svil
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

PININ_MOUSE
NC score	0.074471 (rank : 412)	θ value	0.125558 (rank : 109)
Query Neighborhood Hits	451	Target Neighborhood Hits	777	Shared Neighborhood Hits	73
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

AFF3_HUMAN
NC score	0.074267 (rank : 413)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	451	Target Neighborhood Hits	190	Shared Neighborhood Hits	37
SwissProt Accessions	P51826	Gene names	AFF3, LAF4
Domain Architecture
Description	AF4/FMR2 family member 3 (Protein LAF-4) (Lymphoid nuclear protein related to AF4).

NSD1_HUMAN
NC score	0.074212 (rank : 414)	θ value	θ > 10 (rank : 683)
Query Neighborhood Hits	451	Target Neighborhood Hits	427	Shared Neighborhood Hits	77
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

TGON1_MOUSE
NC score	0.074137 (rank : 415)	θ value	θ > 10 (rank : 815)
Query Neighborhood Hits	451	Target Neighborhood Hits	243	Shared Neighborhood Hits	50
SwissProt Accessions	Q62313	Gene names	Tgoln1, Ttgn1
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 1 precursor (TGN38A).

GA2L3_HUMAN
NC score	0.074134 (rank : 416)	θ value	θ > 10 (rank : 580)
Query Neighborhood Hits	451	Target Neighborhood Hits	189	Shared Neighborhood Hits	47
SwissProt Accessions	Q86XJ1	Gene names	GAS2L3
Domain Architecture	No domain graphic available
Description	GAS2-like protein 3 (Growth arrest-specific 2-like 3).

IRS2_HUMAN
NC score	0.074014 (rank : 417)	θ value	0.365318 (rank : 151)
Query Neighborhood Hits	451	Target Neighborhood Hits	262	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

US6NL_HUMAN
NC score	0.073856 (rank : 418)	θ value	0.0563607 (rank : 90)
Query Neighborhood Hits	451	Target Neighborhood Hits	201	Shared Neighborhood Hits	50
SwissProt Accessions	Q92738, Q15400, Q7L0K9	Gene names	USP6NL, KIAA0019
Domain Architecture	No domain graphic available
Description	USP6 N-terminal-like protein (Related to the N-terminus of tre) (RN- tre).

PS1C2_MOUSE
NC score	0.073675 (rank : 419)	θ value	θ > 10 (rank : 720)
Query Neighborhood Hits	451	Target Neighborhood Hits	59	Shared Neighborhood Hits	19
SwissProt Accessions	Q80ZC9	Gene names	Psors1c2, Spr1
Domain Architecture	No domain graphic available
Description	Psoriasis susceptibility 1 candidate gene 2 protein homolog precursor (SPR1 protein).

NPAS4_MOUSE
NC score	0.073354 (rank : 420)	θ value	θ > 10 (rank : 679)
Query Neighborhood Hits	451	Target Neighborhood Hits	245	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

TAF3_MOUSE
NC score	0.073077 (rank : 421)	θ value	θ > 10 (rank : 803)
Query Neighborhood Hits	451	Target Neighborhood Hits	463	Shared Neighborhood Hits	53
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

GAB1_MOUSE
NC score	0.073039 (rank : 422)	θ value	θ > 10 (rank : 582)
Query Neighborhood Hits	451	Target Neighborhood Hits	233	Shared Neighborhood Hits	84
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

BIN1_HUMAN
NC score	0.072967 (rank : 423)	θ value	θ > 10 (rank : 497)
Query Neighborhood Hits	451	Target Neighborhood Hits	335	Shared Neighborhood Hits	71
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

PCQAP_HUMAN
NC score	0.072773 (rank : 424)	θ value	θ > 10 (rank : 692)
Query Neighborhood Hits	451	Target Neighborhood Hits	549	Shared Neighborhood Hits	75
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

PRR13_MOUSE
NC score	0.072757 (rank : 425)	θ value	θ > 10 (rank : 718)
Query Neighborhood Hits	451	Target Neighborhood Hits	54	Shared Neighborhood Hits	18
SwissProt Accessions	Q9CQJ5, Q3U3U4	Gene names	Prr13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

BPTF_HUMAN
NC score	0.072739 (rank : 426)	θ value	θ > 10 (rank : 500)
Query Neighborhood Hits	451	Target Neighborhood Hits	786	Shared Neighborhood Hits	88
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

IQEC2_MOUSE
NC score	0.072634 (rank : 427)	θ value	0.47712 (rank : 164)
Query Neighborhood Hits	451	Target Neighborhood Hits	417	Shared Neighborhood Hits	83
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

SPR1B_HUMAN
NC score	0.072597 (rank : 428)	θ value	θ > 10 (rank : 781)
Query Neighborhood Hits	451	Target Neighborhood Hits	102	Shared Neighborhood Hits	30
SwissProt Accessions	P22528, P22529, P22530, Q5T524	Gene names	SPRR1B
Domain Architecture	No domain graphic available
Description	Cornifin B (Small proline-rich protein IB) (SPR-IB) (14.9 kDa pancornulin).

CNOT3_HUMAN
NC score	0.072517 (rank : 429)	θ value	θ > 10 (rank : 527)
Query Neighborhood Hits	451	Target Neighborhood Hits	425	Shared Neighborhood Hits	56
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

5NT1B_MOUSE
NC score	0.072513 (rank : 430)	θ value	0.0431538 (rank : 80)
Query Neighborhood Hits	451	Target Neighborhood Hits	78	Shared Neighborhood Hits	21
SwissProt Accessions	Q91YE9, Q91Y48	Gene names	Nt5c1b, Airp
Domain Architecture
Description	Cytosolic 5'-nucleotidase 1B (EC 3.1.3.5) (Cytosolic 5'-nucleotidase IB) (cN1B) (cN-IB) (Autoimmune infertility-related protein).

CDN1C_HUMAN
NC score	0.072386 (rank : 431)	θ value	θ > 10 (rank : 515)
Query Neighborhood Hits	451	Target Neighborhood Hits	168	Shared Neighborhood Hits	35
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

SMR3B_HUMAN
NC score	0.072244 (rank : 432)	θ value	6.88961 (rank : 406)
Query Neighborhood Hits	451	Target Neighborhood Hits	46	Shared Neighborhood Hits	21
SwissProt Accessions	P02814, Q9UBN0, Q9UCT0	Gene names	SMR3B, PBII, PROL3
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog B precursor (Proline-rich protein 3) (Proline-rich peptide P-B) [Contains: Peptide P-A; Peptide D1A].

MARCS_MOUSE
NC score	0.072166 (rank : 433)	θ value	θ > 10 (rank : 637)
Query Neighborhood Hits	451	Target Neighborhood Hits	227	Shared Neighborhood Hits	33
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

TGON2_MOUSE
NC score	0.071903 (rank : 434)	θ value	θ > 10 (rank : 817)
Query Neighborhood Hits	451	Target Neighborhood Hits	277	Shared Neighborhood Hits	55
SwissProt Accessions	Q62314	Gene names	Tgoln2, Ttgn2
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 2 precursor (TGN38B).

ARMX2_MOUSE
NC score	0.071835 (rank : 435)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	451	Target Neighborhood Hits	349	Shared Neighborhood Hits	81
SwissProt Accessions	Q6A058, Q9CXI9	Gene names	Armcx2, Kiaa0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2.

EPN3_MOUSE
NC score	0.071815 (rank : 436)	θ value	θ > 10 (rank : 570)
Query Neighborhood Hits	451	Target Neighborhood Hits	312	Shared Neighborhood Hits	79
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

CNOT3_MOUSE
NC score	0.071507 (rank : 437)	θ value	θ > 10 (rank : 528)
Query Neighborhood Hits	451	Target Neighborhood Hits	504	Shared Neighborhood Hits	65
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

SF3B1_MOUSE
NC score	0.070824 (rank : 438)	θ value	θ > 10 (rank : 767)
Query Neighborhood Hits	451	Target Neighborhood Hits	352	Shared Neighborhood Hits	62
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

MYST3_HUMAN
NC score	0.070749 (rank : 439)	θ value	θ > 10 (rank : 664)
Query Neighborhood Hits	451	Target Neighborhood Hits	772	Shared Neighborhood Hits	93
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

REXO1_HUMAN
NC score	0.070703 (rank : 440)	θ value	θ > 10 (rank : 730)
Query Neighborhood Hits	451	Target Neighborhood Hits	242	Shared Neighborhood Hits	50
SwissProt Accessions	Q8N1G1, Q9ULT2	Gene names	REXO1, ELOABP1, KIAA1138, TCEB3BP1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Elongin A-binding protein 1) (EloA-BP1) (Transcription elongation factor B polypeptide 3-binding protein 1).

BRD3_MOUSE
NC score	0.070676 (rank : 441)	θ value	θ > 10 (rank : 503)
Query Neighborhood Hits	451	Target Neighborhood Hits	402	Shared Neighborhood Hits	41
SwissProt Accessions	Q8K2F0, Q8C665, Q8CAX7, Q9JI25	Gene names	Brd3, Fsrg2
Domain Architecture
Description	Bromodomain-containing protein 3 (Bromodomain-containing FSH-like protein FSRG2).

LCP2_MOUSE
NC score	0.070659 (rank : 442)	θ value	1.81305 (rank : 254)
Query Neighborhood Hits	451	Target Neighborhood Hits	177	Shared Neighborhood Hits	34
SwissProt Accessions	Q60787	Gene names	Lcp2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

TCRG1_MOUSE
NC score	0.070559 (rank : 443)	θ value	θ > 10 (rank : 814)
Query Neighborhood Hits	451	Target Neighborhood Hits	947	Shared Neighborhood Hits	107
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

TM108_HUMAN
NC score	0.070497 (rank : 444)	θ value	θ > 10 (rank : 818)
Query Neighborhood Hits	451	Target Neighborhood Hits	166	Shared Neighborhood Hits	51
SwissProt Accessions	Q6UXF1, Q9BQH1, Q9BW81, Q9C0H3	Gene names	TMEM108, KIAA1690
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

ZAN_HUMAN
NC score	0.070476 (rank : 445)	θ value	θ > 10 (rank : 839)
Query Neighborhood Hits	451	Target Neighborhood Hits	679	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

WBS14_MOUSE
NC score	0.070103 (rank : 446)	θ value	θ > 10 (rank : 835)
Query Neighborhood Hits	451	Target Neighborhood Hits	171	Shared Neighborhood Hits	38
SwissProt Accessions	Q99MZ3, Q99MY9, Q99MZ0, Q99MZ1, Q99MZ2, Q9JLM5	Gene names	Mlxipl, Mio, Wbscr14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein homolog (Mlx interactor) (MLX-interacting protein-like).

ICAL_HUMAN
NC score	0.070072 (rank : 447)	θ value	θ > 10 (rank : 605)
Query Neighborhood Hits	451	Target Neighborhood Hits	275	Shared Neighborhood Hits	54
SwissProt Accessions	P20810, O95360, Q96D08, Q9H1Z5	Gene names	CAST
Domain Architecture
Description	Calpastatin (Calpain inhibitor) (Sperm BS-17 component).

CA106_MOUSE
NC score	0.069948 (rank : 448)	θ value	1.81305 (rank : 246)
Query Neighborhood Hits	451	Target Neighborhood Hits	89	Shared Neighborhood Hits	24
SwissProt Accessions	Q7TN12, Q7TN27, Q8BGK3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106 homolog.

CAC1G_HUMAN
NC score	0.069623 (rank : 449)	θ value	θ > 10 (rank : 507)
Query Neighborhood Hits	451	Target Neighborhood Hits	587	Shared Neighborhood Hits	136
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

PO6F2_MOUSE
NC score	0.069587 (rank : 450)	θ value	1.06291 (rank : 213)
Query Neighborhood Hits	451	Target Neighborhood Hits	639	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

PAF49_HUMAN
NC score	0.069583 (rank : 451)	θ value	θ > 10 (rank : 690)
Query Neighborhood Hits	451	Target Neighborhood Hits	169	Shared Neighborhood Hits	42
SwissProt Accessions	O15446, Q32N11, Q7Z5U2, Q9UPF6	Gene names	CD3EAP, ASE1, CAST, PAF49
Domain Architecture	No domain graphic available
Description	RNA polymerase I-associated factor PAF49 (Anti-sense to ERCC-1 protein) (ASE-1) (CD3-epsilon-associated protein) (CD3E-associated protein) (CAST).

SF3B1_HUMAN
NC score	0.069493 (rank : 452)	θ value	θ > 10 (rank : 766)
Query Neighborhood Hits	451	Target Neighborhood Hits	341	Shared Neighborhood Hits	58
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

IQEC2_HUMAN
NC score	0.069481 (rank : 453)	θ value	0.47712 (rank : 163)
Query Neighborhood Hits	451	Target Neighborhood Hits	403	Shared Neighborhood Hits	81
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

TCRG1_HUMAN
NC score	0.069439 (rank : 454)	θ value	θ > 10 (rank : 813)
Query Neighborhood Hits	451	Target Neighborhood Hits	929	Shared Neighborhood Hits	106
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

MILK1_HUMAN
NC score	0.069342 (rank : 455)	θ value	θ > 10 (rank : 647)
Query Neighborhood Hits	451	Target Neighborhood Hits	427	Shared Neighborhood Hits	81
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

ZIM10_MOUSE
NC score	0.069191 (rank : 456)	θ value	3.0926 (rank : 326)
Query Neighborhood Hits	451	Target Neighborhood Hits	430	Shared Neighborhood Hits	91
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

DOK2_MOUSE
NC score	0.069066 (rank : 457)	θ value	θ > 10 (rank : 557)
Query Neighborhood Hits	451	Target Neighborhood Hits	244	Shared Neighborhood Hits	81
SwissProt Accessions	O70469, O70272, Q99KL1	Gene names	Dok2, Frip
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)) (Dok- related protein) (Dok-R) (IL-four receptor-interacting protein) (FRIP).

UBP36_HUMAN
NC score	0.068818 (rank : 458)	θ value	0.00869519 (rank : 63)
Query Neighborhood Hits	451	Target Neighborhood Hits	232	Shared Neighborhood Hits	46
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

EVL_HUMAN
NC score	0.068720 (rank : 459)	θ value	θ > 10 (rank : 573)
Query Neighborhood Hits	451	Target Neighborhood Hits	260	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UI08, O95884, Q7Z522, Q8TBV1, Q9UF25, Q9UIC2	Gene names	EVL, RNB6
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

S23IP_MOUSE
NC score	0.068479 (rank : 460)	θ value	θ > 10 (rank : 749)
Query Neighborhood Hits	451	Target Neighborhood Hits	363	Shared Neighborhood Hits	89
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

PRPE_HUMAN
NC score	0.068434 (rank : 461)	θ value	θ > 10 (rank : 716)
Query Neighborhood Hits	451	Target Neighborhood Hits	44	Shared Neighborhood Hits	16
SwissProt Accessions	P02811	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide P-E (IB-9).

ANR11_HUMAN
NC score	0.068221 (rank : 462)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	451	Target Neighborhood Hits	1289	Shared Neighborhood Hits	141
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

GAK17_HUMAN
NC score	0.068217 (rank : 463)	θ value	θ > 10 (rank : 586)
Query Neighborhood Hits	451	Target Neighborhood Hits	21	Shared Neighborhood Hits	9
SwissProt Accessions	P62689	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_11q22.1 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein].

IL3B2_MOUSE
NC score	0.068171 (rank : 464)	θ value	θ > 10 (rank : 611)
Query Neighborhood Hits	451	Target Neighborhood Hits	372	Shared Neighborhood Hits	97
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

GAK9_HUMAN
NC score	0.068112 (rank : 465)	θ value	θ > 10 (rank : 591)
Query Neighborhood Hits	451	Target Neighborhood Hits	22	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UKH8	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q13.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K104 Gag protein) [Contains: Matrix protein].

EFS_HUMAN
NC score	0.068058 (rank : 466)	θ value	θ > 10 (rank : 562)
Query Neighborhood Hits	451	Target Neighborhood Hits	348	Shared Neighborhood Hits	75
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

GAK15_HUMAN
NC score	0.067854 (rank : 467)	θ value	θ > 10 (rank : 585)
Query Neighborhood Hits	451	Target Neighborhood Hits	19	Shared Neighborhood Hits	9
SwissProt Accessions	P62688	Gene names	ERVK4
Domain Architecture	No domain graphic available
Description	HERV-K_3q21.2 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(I) Gag protein).

NPAS4_HUMAN
NC score	0.067710 (rank : 468)	θ value	θ > 10 (rank : 678)
Query Neighborhood Hits	451	Target Neighborhood Hits	214	Shared Neighborhood Hits	56
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

HSF1_MOUSE
NC score	0.067703 (rank : 469)	θ value	θ > 10 (rank : 603)
Query Neighborhood Hits	451	Target Neighborhood Hits	267	Shared Neighborhood Hits	72
SwissProt Accessions	P38532, O70462	Gene names	Hsf1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

NRX2A_HUMAN
NC score	0.067568 (rank : 470)	θ value	θ > 10 (rank : 681)
Query Neighborhood Hits	451	Target Neighborhood Hits	614	Shared Neighborhood Hits	127
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

PKHA6_MOUSE
NC score	0.067416 (rank : 471)	θ value	θ > 10 (rank : 705)
Query Neighborhood Hits	451	Target Neighborhood Hits	591	Shared Neighborhood Hits	86
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

CMTA2_MOUSE
NC score	0.067364 (rank : 472)	θ value	0.365318 (rank : 145)
Query Neighborhood Hits	451	Target Neighborhood Hits	216	Shared Neighborhood Hits	34
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

IL3RB_MOUSE
NC score	0.067243 (rank : 473)	θ value	θ > 10 (rank : 612)
Query Neighborhood Hits	451	Target Neighborhood Hits	355	Shared Neighborhood Hits	95
SwissProt Accessions	P26955	Gene names	Csf2rb, Aic2b, Csf2rb1, Il3rb1
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen).

JIP1_MOUSE
NC score	0.067162 (rank : 474)	θ value	θ > 10 (rank : 618)
Query Neighborhood Hits	451	Target Neighborhood Hits	259	Shared Neighborhood Hits	67
SwissProt Accessions	Q9WVI9, O35145, Q925J8, Q9R1H9, Q9R1Z1, Q9WVI7, Q9WVI8	Gene names	Mapk8ip1, Ib1, Jip1, Mapk8ip, Prkm8ip
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain-1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

DACT1_HUMAN
NC score	0.066977 (rank : 475)	θ value	θ > 10 (rank : 548)
Query Neighborhood Hits	451	Target Neighborhood Hits	228	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NYF0, Q86TY0	Gene names	DACT1, DPR1, HNG3
Domain Architecture	No domain graphic available
Description	Dapper homolog 1 (hDPR1) (Heptacellular carcinoma novel gene 3 protein).

G3BP_MOUSE
NC score	0.066971 (rank : 476)	θ value	0.0563607 (rank : 86)
Query Neighborhood Hits	451	Target Neighborhood Hits	209	Shared Neighborhood Hits	25
SwissProt Accessions	P97855	Gene names	G3bp, G3bp1
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 1 (EC 3.6.1.-) (ATP- dependent DNA helicase VIII) (GAP SH3-domain-binding protein 1) (G3BP- 1) (HDH-VIII).

BLNK_HUMAN
NC score	0.066902 (rank : 477)	θ value	θ > 10 (rank : 498)
Query Neighborhood Hits	451	Target Neighborhood Hits	228	Shared Neighborhood Hits	51
SwissProt Accessions	Q8WV28, O75498, O75499	Gene names	BLNK, BASH, SLP65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (SLP-65).

SELPL_HUMAN
NC score	0.066809 (rank : 478)	θ value	θ > 10 (rank : 756)
Query Neighborhood Hits	451	Target Neighborhood Hits	68	Shared Neighborhood Hits	15
SwissProt Accessions	Q14242, Q12775	Gene names	SELPLG
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand) (CD162 antigen).

ACINU_MOUSE
NC score	0.066707 (rank : 479)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	451	Target Neighborhood Hits	712	Shared Neighborhood Hits	76
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

AMPH_HUMAN
NC score	0.066637 (rank : 480)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	451	Target Neighborhood Hits	455	Shared Neighborhood Hits	74
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

R3HD2_MOUSE
NC score	0.066615 (rank : 481)	θ value	θ > 10 (rank : 723)
Query Neighborhood Hits	451	Target Neighborhood Hits	397	Shared Neighborhood Hits	82
SwissProt Accessions	Q80TM6, Q80YB1, Q8BLS5, Q9CW50	Gene names	R3hdm2, Kiaa1002
Domain Architecture
Description	R3H domain-containing protein 2.

MYPN_HUMAN
NC score	0.066573 (rank : 482)	θ value	0.00020696 (rank : 26)
Query Neighborhood Hits	451	Target Neighborhood Hits	418	Shared Neighborhood Hits	36
SwissProt Accessions	Q86TC9, Q5VV35, Q5VV36, Q86T37, Q8N3L4, Q96K90, Q96KF5	Gene names	MYPN, MYOP
Domain Architecture	No domain graphic available
Description	Myopalladin (145 kDa sarcomeric protein).

CMTA2_HUMAN
NC score	0.066512 (rank : 483)	θ value	1.06291 (rank : 201)
Query Neighborhood Hits	451	Target Neighborhood Hits	199	Shared Neighborhood Hits	26
SwissProt Accessions	O94983, Q7Z6M8, Q8N3V0, Q8NDG4, Q96G17	Gene names	CAMTA2, KIAA0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

IRS2_MOUSE
NC score	0.066466 (rank : 484)	θ value	θ > 10 (rank : 615)
Query Neighborhood Hits	451	Target Neighborhood Hits	248	Shared Neighborhood Hits	46
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

RAI1_HUMAN
NC score	0.066316 (rank : 485)	θ value	8.99809 (rank : 436)
Query Neighborhood Hits	451	Target Neighborhood Hits	360	Shared Neighborhood Hits	69
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

OXR1_MOUSE
NC score	0.066229 (rank : 486)	θ value	θ > 10 (rank : 689)
Query Neighborhood Hits	451	Target Neighborhood Hits	516	Shared Neighborhood Hits	59
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

DCC_MOUSE
NC score	0.066208 (rank : 487)	θ value	θ > 10 (rank : 549)
Query Neighborhood Hits	451	Target Neighborhood Hits	896	Shared Neighborhood Hits	146
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

SPEG_MOUSE
NC score	0.066091 (rank : 488)	θ value	1.06291 (rank : 217)
Query Neighborhood Hits	451	Target Neighborhood Hits	1959	Shared Neighborhood Hits	219
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

ZYX_MOUSE
NC score	0.066024 (rank : 489)	θ value	0.62314 (rank : 181)
Query Neighborhood Hits	451	Target Neighborhood Hits	347	Shared Neighborhood Hits	52
SwissProt Accessions	Q62523, P70461	Gene names	Zyx
Domain Architecture
Description	Zyxin.

EFS_MOUSE
NC score	0.066022 (rank : 490)	θ value	θ > 10 (rank : 563)
Query Neighborhood Hits	451	Target Neighborhood Hits	389	Shared Neighborhood Hits	86
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

APC_HUMAN
NC score	0.065966 (rank : 491)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	451	Target Neighborhood Hits	603	Shared Neighborhood Hits	89
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

SOX30_MOUSE
NC score	0.065849 (rank : 492)	θ value	8.99809 (rank : 441)
Query Neighborhood Hits	451	Target Neighborhood Hits	374	Shared Neighborhood Hits	110
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

BRDT_MOUSE
NC score	0.065573 (rank : 493)	θ value	2.36792 (rank : 268)
Query Neighborhood Hits	451	Target Neighborhood Hits	243	Shared Neighborhood Hits	25
SwissProt Accessions	Q91Y44, Q59HJ4	Gene names	Brdt, Fsrg3
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein) (Bromodomain- containing female sterile homeotic-like protein).

GAK19_HUMAN
NC score	0.065536 (rank : 494)	θ value	θ > 10 (rank : 588)
Query Neighborhood Hits	451	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	P62691	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_4p16.1 provirus ancestral Gag polyprotein (Gag polyprotein).

NASP_HUMAN
NC score	0.065256 (rank : 495)	θ value	θ > 10 (rank : 665)
Query Neighborhood Hits	451	Target Neighborhood Hits	709	Shared Neighborhood Hits	57
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

ALMS1_HUMAN
NC score	0.065126 (rank : 496)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	451	Target Neighborhood Hits	356	Shared Neighborhood Hits	62
SwissProt Accessions	Q8TCU4, Q53S05, Q580Q8, Q86VP9, Q9Y4G4	Gene names	ALMS1, KIAA0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1.

NELFA_MOUSE
NC score	0.064779 (rank : 497)	θ value	θ > 10 (rank : 670)
Query Neighborhood Hits	451	Target Neighborhood Hits	195	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BG30, Q8BVE4, Q8VEI7, Q9CSJ9, Q9Z1V9	Gene names	Whsc2, Nelfa, Whsc2h
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 homolog) (mWHSC2).

SFR12_HUMAN
NC score	0.064602 (rank : 498)	θ value	1.38821 (rank : 238)
Query Neighborhood Hits	451	Target Neighborhood Hits	553	Shared Neighborhood Hits	38
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

SHAN1_HUMAN
NC score	0.064348 (rank : 499)	θ value	θ > 10 (rank : 773)
Query Neighborhood Hits	451	Target Neighborhood Hits	1041	Shared Neighborhood Hits	104
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

RAI1_MOUSE
NC score	0.064059 (rank : 500)	θ value	θ > 10 (rank : 725)
Query Neighborhood Hits	451	Target Neighborhood Hits	344	Shared Neighborhood Hits	70
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

EMSY_MOUSE
NC score	0.063617 (rank : 501)	θ value	θ > 10 (rank : 566)
Query Neighborhood Hits	451	Target Neighborhood Hits	294	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BMB0, Q5FWK5, Q80XU1, Q8VDW9	Gene names	Emsy
Domain Architecture
Description	Protein EMSY.

ZYX_HUMAN
NC score	0.063353 (rank : 502)	θ value	1.38821 (rank : 242)
Query Neighborhood Hits	451	Target Neighborhood Hits	387	Shared Neighborhood Hits	65
SwissProt Accessions	Q15942	Gene names	ZYX
Domain Architecture
Description	Zyxin (Zyxin-2).

JPH2_MOUSE
NC score	0.063277 (rank : 503)	θ value	1.38821 (rank : 232)
Query Neighborhood Hits	451	Target Neighborhood Hits	279	Shared Neighborhood Hits	59
SwissProt Accessions	Q9ET78, Q9ET79	Gene names	Jph2, Jp2
Domain Architecture	No domain graphic available
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

NUP53_HUMAN
NC score	0.063260 (rank : 504)	θ value	θ > 10 (rank : 687)
Query Neighborhood Hits	451	Target Neighborhood Hits	156	Shared Neighborhood Hits	55
SwissProt Accessions	Q8NFH5, Q4ZFZ9, Q53S95, Q8TDJ1	Gene names	NUP35, MP44, NUP53
Domain Architecture	No domain graphic available
Description	Nucleoporin NUP53 (Nuclear pore complex protein Nup53) (Nucleoporin Nup35) (35 kDa nucleoporin) (Mitotic phosphoprotein 44) (MP-44).

ECM1_HUMAN
NC score	0.063107 (rank : 505)	θ value	θ > 10 (rank : 561)
Query Neighborhood Hits	451	Target Neighborhood Hits	182	Shared Neighborhood Hits	59
SwissProt Accessions	Q16610	Gene names	ECM1
Domain Architecture
Description	Extracellular matrix protein 1 precursor (Secretory component p85).

GAK14_HUMAN
NC score	0.063066 (rank : 506)	θ value	θ > 10 (rank : 584)
Query Neighborhood Hits	451	Target Neighborhood Hits	18	Shared Neighborhood Hits	9
SwissProt Accessions	P62687	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_16p3.3 provirus ancestral Gag polyprotein (Gag polyprotein).

BRD3_HUMAN
NC score	0.062834 (rank : 507)	θ value	θ > 10 (rank : 502)
Query Neighborhood Hits	451	Target Neighborhood Hits	369	Shared Neighborhood Hits	40
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

MAST4_HUMAN
NC score	0.062771 (rank : 508)	θ value	4.03905 (rank : 336)
Query Neighborhood Hits	451	Target Neighborhood Hits	1804	Shared Neighborhood Hits	215
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

ABI3_MOUSE
NC score	0.062758 (rank : 509)	θ value	5.27518 (rank : 350)
Query Neighborhood Hits	451	Target Neighborhood Hits	227	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

BRD2_HUMAN
NC score	0.062745 (rank : 510)	θ value	θ > 10 (rank : 501)
Query Neighborhood Hits	451	Target Neighborhood Hits	242	Shared Neighborhood Hits	26
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

SRBP1_MOUSE
NC score	0.062660 (rank : 511)	θ value	θ > 10 (rank : 788)
Query Neighborhood Hits	451	Target Neighborhood Hits	384	Shared Neighborhood Hits	87
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

SDC3_MOUSE
NC score	0.062510 (rank : 512)	θ value	θ > 10 (rank : 755)
Query Neighborhood Hits	451	Target Neighborhood Hits	107	Shared Neighborhood Hits	28
SwissProt Accessions	Q64519, Q3UDD9, Q6ZQA4, Q7TQD4	Gene names	Sdc3, Kiaa0468
Domain Architecture
Description	Syndecan-3 precursor (SYND3).

EMSY_HUMAN
NC score	0.062256 (rank : 513)	θ value	θ > 10 (rank : 565)
Query Neighborhood Hits	451	Target Neighborhood Hits	296	Shared Neighborhood Hits	50
SwissProt Accessions	Q7Z589, Q4G109, Q8NBU6, Q8TE50, Q9H8I9, Q9NRH0	Gene names	EMSY, C11orf30
Domain Architecture
Description	Protein EMSY.

RPB1_HUMAN
NC score	0.062170 (rank : 514)	θ value	θ > 10 (rank : 740)
Query Neighborhood Hits	451	Target Neighborhood Hits	362	Shared Neighborhood Hits	55
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

PPRB_HUMAN
NC score	0.061881 (rank : 515)	θ value	θ > 10 (rank : 710)
Query Neighborhood Hits	451	Target Neighborhood Hits	311	Shared Neighborhood Hits	60
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

RC3H1_HUMAN
NC score	0.061814 (rank : 516)	θ value	θ > 10 (rank : 728)
Query Neighborhood Hits	451	Target Neighborhood Hits	433	Shared Neighborhood Hits	93
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

PARM1_MOUSE
NC score	0.061689 (rank : 517)	θ value	θ > 10 (rank : 691)
Query Neighborhood Hits	451	Target Neighborhood Hits	140	Shared Neighborhood Hits	30
SwissProt Accessions	Q923D3, Q3TTV0, Q3UFU4	Gene names
Domain Architecture	No domain graphic available
Description	Protein PARM-1 precursor.

MEF2B_MOUSE
NC score	0.061482 (rank : 518)	θ value	θ > 10 (rank : 645)
Query Neighborhood Hits	451	Target Neighborhood Hits	218	Shared Neighborhood Hits	52
SwissProt Accessions	O55087, O55088, O55089, O55090, O55231, Q61843	Gene names	Mef2b
Domain Architecture
Description	Myocyte-specific enhancer factor 2B.

LEO1_HUMAN
NC score	0.061474 (rank : 519)	θ value	θ > 10 (rank : 627)
Query Neighborhood Hits	451	Target Neighborhood Hits	958	Shared Neighborhood Hits	69
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

LR37B_HUMAN
NC score	0.061467 (rank : 520)	θ value	0.279714 (rank : 137)
Query Neighborhood Hits	451	Target Neighborhood Hits	392	Shared Neighborhood Hits	41
SwissProt Accessions	Q96QE4, Q5YKG6	Gene names	LRRC37B
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37B precursor (C66 SLIT-like testicular protein).

NUCKS_MOUSE
NC score	0.061366 (rank : 521)	θ value	θ > 10 (rank : 685)
Query Neighborhood Hits	451	Target Neighborhood Hits	114	Shared Neighborhood Hits	18
SwissProt Accessions	Q80XU3, Q8BVD8	Gene names	Nucks1, Nucks
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (JC7).

PF21B_MOUSE
NC score	0.061323 (rank : 522)	θ value	θ > 10 (rank : 699)
Query Neighborhood Hits	451	Target Neighborhood Hits	278	Shared Neighborhood Hits	70
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PO6F2_HUMAN
NC score	0.061265 (rank : 523)	θ value	1.81305 (rank : 257)
Query Neighborhood Hits	451	Target Neighborhood Hits	618	Shared Neighborhood Hits	79
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

NOL3_MOUSE
NC score	0.061135 (rank : 524)	θ value	θ > 10 (rank : 677)
Query Neighborhood Hits	451	Target Neighborhood Hits	97	Shared Neighborhood Hits	24
SwissProt Accessions	Q9D1X0	Gene names	Nol3
Domain Architecture
Description	Nucleolar protein 3.

TB182_HUMAN
NC score	0.061109 (rank : 525)	θ value	θ > 10 (rank : 807)
Query Neighborhood Hits	451	Target Neighborhood Hits	414	Shared Neighborhood Hits	58
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

PO121_MOUSE
NC score	0.060957 (rank : 526)	θ value	θ > 10 (rank : 707)
Query Neighborhood Hits	451	Target Neighborhood Hits	345	Shared Neighborhood Hits	55
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

GP112_HUMAN
NC score	0.060745 (rank : 527)	θ value	θ > 10 (rank : 595)
Query Neighborhood Hits	451	Target Neighborhood Hits	441	Shared Neighborhood Hits	48
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

THOC2_HUMAN
NC score	0.060731 (rank : 528)	θ value	8.99809 (rank : 444)
Query Neighborhood Hits	451	Target Neighborhood Hits	337	Shared Neighborhood Hits	39
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

GAK13_HUMAN
NC score	0.060577 (rank : 529)	θ value	θ > 10 (rank : 583)
Query Neighborhood Hits	451	Target Neighborhood Hits	21	Shared Neighborhood Hits	9
SwissProt Accessions	P62686	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1p13.3 provirus ancestral Gag polyprotein (Gag polyprotein).

RPB1_MOUSE
NC score	0.060427 (rank : 530)	θ value	θ > 10 (rank : 741)
Query Neighborhood Hits	451	Target Neighborhood Hits	363	Shared Neighborhood Hits	53
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RCOR2_MOUSE
NC score	0.060237 (rank : 531)	θ value	4.03905 (rank : 341)
Query Neighborhood Hits	451	Target Neighborhood Hits	107	Shared Neighborhood Hits	26
SwissProt Accessions	Q8C796, Q9JMK4	Gene names	Rcor2
Domain Architecture	No domain graphic available
Description	REST corepressor 2 (M-CoREST).

DDEF1_MOUSE
NC score	0.060231 (rank : 532)	θ value	5.27518 (rank : 356)
Query Neighborhood Hits	451	Target Neighborhood Hits	592	Shared Neighborhood Hits	74
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

TITIN_HUMAN
NC score	0.060229 (rank : 533)	θ value	0.62314 (rank : 177)
Query Neighborhood Hits	451	Target Neighborhood Hits	2923	Shared Neighborhood Hits	194
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

MUCEN_MOUSE
NC score	0.060223 (rank : 534)	θ value	θ > 10 (rank : 661)
Query Neighborhood Hits	451	Target Neighborhood Hits	65	Shared Neighborhood Hits	15
SwissProt Accessions	Q9R0H2, Q78KL2, Q9DCN9, Q9ULC1, Q9Z2I1	Gene names	Emcn, Muc14
Domain Architecture	No domain graphic available
Description	Endomucin precursor (Endomucin-1/2).

CITE4_HUMAN
NC score	0.060206 (rank : 535)	θ value	5.27518 (rank : 352)
Query Neighborhood Hits	451	Target Neighborhood Hits	67	Shared Neighborhood Hits	26
SwissProt Accessions	Q96RK1	Gene names	CITED4, MRG2
Domain Architecture	No domain graphic available
Description	Cbp/p300-interacting transactivator 4 (MSG1-related protein 2) (MRG- 2).

FA53C_MOUSE
NC score	0.060175 (rank : 536)	θ value	1.81305 (rank : 250)
Query Neighborhood Hits	451	Target Neighborhood Hits	40	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BXQ8, Q3U4J2	Gene names	Fam53c
Domain Architecture	No domain graphic available
Description	Protein FAM53C.

SETD2_HUMAN
NC score	0.060141 (rank : 537)	θ value	θ > 10 (rank : 761)
Query Neighborhood Hits	451	Target Neighborhood Hits	412	Shared Neighborhood Hits	57
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

EVL_MOUSE
NC score	0.060015 (rank : 538)	θ value	θ > 10 (rank : 574)
Query Neighborhood Hits	451	Target Neighborhood Hits	203	Shared Neighborhood Hits	55
SwissProt Accessions	P70429, Q9ERU8	Gene names	Evl
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

CF010_HUMAN
NC score	0.059958 (rank : 539)	θ value	θ > 10 (rank : 517)
Query Neighborhood Hits	451	Target Neighborhood Hits	329	Shared Neighborhood Hits	32
SwissProt Accessions	Q5SRN2, Q5SPI9, Q5SPJ0, Q5SPK9, Q5SPL0, Q5SRN3, Q5TG25, Q5TG26, Q8N4B6	Gene names	C6orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf10.

UBP42_HUMAN
NC score	0.059821 (rank : 540)	θ value	θ > 10 (rank : 828)
Query Neighborhood Hits	451	Target Neighborhood Hits	445	Shared Neighborhood Hits	79
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

LEUK_MOUSE
NC score	0.059611 (rank : 541)	θ value	θ > 10 (rank : 630)
Query Neighborhood Hits	451	Target Neighborhood Hits	147	Shared Neighborhood Hits	27
SwissProt Accessions	P15702	Gene names	Spn
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Ly- 48) (B cell differentiation antigen LP-3) (CD43 antigen).

ETV3_HUMAN
NC score	0.059605 (rank : 542)	θ value	θ > 10 (rank : 572)
Query Neighborhood Hits	451	Target Neighborhood Hits	312	Shared Neighborhood Hits	76
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

FR1OP_MOUSE
NC score	0.059557 (rank : 543)	θ value	0.0961366 (rank : 98)
Query Neighborhood Hits	451	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q66JX5, Q32P17, Q8BH91	Gene names	Fgfr1op
Domain Architecture	No domain graphic available
Description	FGFR1 oncogene partner.

PKHA6_HUMAN
NC score	0.059545 (rank : 544)	θ value	1.81305 (rank : 256)
Query Neighborhood Hits	451	Target Neighborhood Hits	556	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

G3PT_MOUSE
NC score	0.059450 (rank : 545)	θ value	5.27518 (rank : 361)
Query Neighborhood Hits	451	Target Neighborhood Hits	78	Shared Neighborhood Hits	34
SwissProt Accessions	Q64467, Q60650	Gene names	Gapdhs, Gapd-s, Gapds
Domain Architecture
Description	Glyceraldehyde-3-phosphate dehydrogenase, testis-specific (EC 1.2.1.12) (Spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2) (GAPDH-2).

CRSP7_HUMAN
NC score	0.059346 (rank : 546)	θ value	θ > 10 (rank : 535)
Query Neighborhood Hits	451	Target Neighborhood Hits	247	Shared Neighborhood Hits	49
SwissProt Accessions	O95402	Gene names	CRSP7, ARC70
Domain Architecture
Description	CRSP complex subunit 7 (Cofactor required for Sp1 transcriptional activation subunit 7) (Transcriptional coactivator CRSP70) (Activator- recruited cofactor 70 kDa component) (ARC70).

SMRC2_MOUSE
NC score	0.059298 (rank : 547)	θ value	θ > 10 (rank : 776)
Query Neighborhood Hits	451	Target Neighborhood Hits	487	Shared Neighborhood Hits	67
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

PKHA4_MOUSE
NC score	0.059276 (rank : 548)	θ value	θ > 10 (rank : 704)
Query Neighborhood Hits	451	Target Neighborhood Hits	202	Shared Neighborhood Hits	32
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

CN092_MOUSE
NC score	0.059253 (rank : 549)	θ value	θ > 10 (rank : 526)
Query Neighborhood Hits	451	Target Neighborhood Hits	206	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BU11, Q80UI2, Q99PN9, Q9CS16	Gene names
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

YETS2_HUMAN
NC score	0.059051 (rank : 550)	θ value	4.03905 (rank : 348)
Query Neighborhood Hits	451	Target Neighborhood Hits	212	Shared Neighborhood Hits	46
SwissProt Accessions	Q9ULM3, Q641P6, Q9NW96	Gene names	YEATS2, KIAA1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

SOX30_HUMAN
NC score	0.059049 (rank : 551)	θ value	θ > 10 (rank : 780)
Query Neighborhood Hits	451	Target Neighborhood Hits	305	Shared Neighborhood Hits	69
SwissProt Accessions	O94993, O94995, Q8IYX6	Gene names	SOX30
Domain Architecture
Description	Transcription factor SOX-30.

NFRKB_HUMAN
NC score	0.058951 (rank : 552)	θ value	θ > 10 (rank : 674)
Query Neighborhood Hits	451	Target Neighborhood Hits	211	Shared Neighborhood Hits	39
SwissProt Accessions	Q6P4R8, Q12869, Q15312, Q9H048	Gene names	NFRKB
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

TACC2_HUMAN
NC score	0.058938 (rank : 553)	θ value	θ > 10 (rank : 801)
Query Neighborhood Hits	451	Target Neighborhood Hits	856	Shared Neighborhood Hits	97
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

NHS_HUMAN
NC score	0.058643 (rank : 554)	θ value	θ > 10 (rank : 676)
Query Neighborhood Hits	451	Target Neighborhood Hits	198	Shared Neighborhood Hits	47
SwissProt Accessions	Q6T4R5, Q5J7Q0, Q5J7Q1, Q68DR5	Gene names	NHS
Domain Architecture	No domain graphic available
Description	Nance-Horan syndrome protein (Congenital cataracts and dental anomalies protein).

CF118_HUMAN
NC score	0.058572 (rank : 555)	θ value	0.21417 (rank : 123)
Query Neighborhood Hits	451	Target Neighborhood Hits	154	Shared Neighborhood Hits	8
SwissProt Accessions	Q5T5N4, Q8TC11	Gene names	C6orf118
Domain Architecture	No domain graphic available
Description	Protein C6orf118.

TP53B_HUMAN
NC score	0.058569 (rank : 556)	θ value	θ > 10 (rank : 821)
Query Neighborhood Hits	451	Target Neighborhood Hits	413	Shared Neighborhood Hits	67
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

DAB1_HUMAN
NC score	0.058550 (rank : 557)	θ value	θ > 10 (rank : 547)
Query Neighborhood Hits	451	Target Neighborhood Hits	219	Shared Neighborhood Hits	69
SwissProt Accessions	O75553, Q9NYA8	Gene names	DAB1
Domain Architecture
Description	Disabled homolog 1.

ANTR1_MOUSE
NC score	0.058513 (rank : 558)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	451	Target Neighborhood Hits	143	Shared Neighborhood Hits	50
SwissProt Accessions	Q9CZ52	Gene names	Antxr1, Atr, Tem8
Domain Architecture
Description	Anthrax toxin receptor 1 precursor (Tumor endothelial marker 8).

ENAH_HUMAN
NC score	0.058449 (rank : 559)	θ value	θ > 10 (rank : 567)
Query Neighborhood Hits	451	Target Neighborhood Hits	784	Shared Neighborhood Hits	85
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

SDC3_HUMAN
NC score	0.058443 (rank : 560)	θ value	θ > 10 (rank : 754)
Query Neighborhood Hits	451	Target Neighborhood Hits	103	Shared Neighborhood Hits	29
SwissProt Accessions	O75056, Q5T1Z6, Q5T1Z7, Q96CT3, Q96PR8	Gene names	SDC3, KIAA0468
Domain Architecture
Description	Syndecan-3 (SYND3).

SFRS8_HUMAN
NC score	0.058322 (rank : 561)	θ value	θ > 10 (rank : 770)
Query Neighborhood Hits	451	Target Neighborhood Hits	166	Shared Neighborhood Hits	29
SwissProt Accessions	Q12872	Gene names	SFRS8, SWAP
Domain Architecture
Description	Splicing factor, arginine/serine-rich 8 (Suppressor of white apricot protein homolog).

NEUM_HUMAN
NC score	0.058312 (rank : 562)	θ value	θ > 10 (rank : 671)
Query Neighborhood Hits	451	Target Neighborhood Hits	132	Shared Neighborhood Hits	27
SwissProt Accessions	P17677	Gene names	GAP43
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (PP46) (Neural phosphoprotein B-50).

CT174_HUMAN
NC score	0.058252 (rank : 563)	θ value	θ > 10 (rank : 543)
Query Neighborhood Hits	451	Target Neighborhood Hits	181	Shared Neighborhood Hits	49
SwissProt Accessions	Q5JPB2, Q5TDR4, Q8TCP0	Gene names	C20orf174
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf174.

CS007_HUMAN
NC score	0.058115 (rank : 564)	θ value	θ > 10 (rank : 536)
Query Neighborhood Hits	451	Target Neighborhood Hits	401	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

NEUM_MOUSE
NC score	0.058049 (rank : 565)	θ value	θ > 10 (rank : 672)
Query Neighborhood Hits	451	Target Neighborhood Hits	149	Shared Neighborhood Hits	24
SwissProt Accessions	P06837	Gene names	Gap43, Basp2
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (Calmodulin-binding protein P-57).

SMRC2_HUMAN
NC score	0.058048 (rank : 566)	θ value	θ > 10 (rank : 775)
Query Neighborhood Hits	451	Target Neighborhood Hits	499	Shared Neighborhood Hits	71
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

SF3B2_HUMAN
NC score	0.058009 (rank : 567)	θ value	4.03905 (rank : 342)
Query Neighborhood Hits	451	Target Neighborhood Hits	157	Shared Neighborhood Hits	26
SwissProt Accessions	Q13435	Gene names	SF3B2, SAP145
Domain Architecture
Description	Splicing factor 3B subunit 2 (Spliceosome-associated protein 145) (SAP 145) (SF3b150) (Pre-mRNA-splicing factor SF3b 145 kDa subunit).

ZAN_MOUSE
NC score	0.057938 (rank : 568)	θ value	θ > 10 (rank : 840)
Query Neighborhood Hits	451	Target Neighborhood Hits	808	Shared Neighborhood Hits	40
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

ESCO1_HUMAN
NC score	0.057574 (rank : 569)	θ value	θ > 10 (rank : 571)
Query Neighborhood Hits	451	Target Neighborhood Hits	361	Shared Neighborhood Hits	38
SwissProt Accessions	Q5FWF5, Q69YG4, Q69YS3, Q6IMD7, Q8N3Z5, Q8NBG2, Q96PX7	Gene names	ESCO1, EFO1, KIAA1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1) (Establishment factor- like protein 1) (EFO1p) (hEFO1) (CTF7 homolog 1).

MKL1_HUMAN
NC score	0.057488 (rank : 570)	θ value	3.0926 (rank : 304)
Query Neighborhood Hits	451	Target Neighborhood Hits	232	Shared Neighborhood Hits	46
SwissProt Accessions	Q969V6, Q8TCL1, Q96SC5, Q96SC6, Q9P2B0	Gene names	MKL1, KIAA1438, MAL
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein) (Megakaryocytic acute leukemia protein).

TR150_MOUSE
NC score	0.057452 (rank : 571)	θ value	θ > 10 (rank : 824)
Query Neighborhood Hits	451	Target Neighborhood Hits	468	Shared Neighborhood Hits	55
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

PCQAP_MOUSE
NC score	0.057396 (rank : 572)	θ value	θ > 10 (rank : 693)
Query Neighborhood Hits	451	Target Neighborhood Hits	506	Shared Neighborhood Hits	72
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

MYO15_MOUSE
NC score	0.057333 (rank : 573)	θ value	θ > 10 (rank : 663)
Query Neighborhood Hits	451	Target Neighborhood Hits	467	Shared Neighborhood Hits	118
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

TXLNB_HUMAN
NC score	0.057318 (rank : 574)	θ value	θ > 10 (rank : 826)
Query Neighborhood Hits	451	Target Neighborhood Hits	912	Shared Neighborhood Hits	117
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

INCE_HUMAN
NC score	0.057300 (rank : 575)	θ value	0.0330416 (rank : 72)
Query Neighborhood Hits	451	Target Neighborhood Hits	978	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

BRDT_HUMAN
NC score	0.057280 (rank : 576)	θ value	θ > 10 (rank : 505)
Query Neighborhood Hits	451	Target Neighborhood Hits	280	Shared Neighborhood Hits	19
SwissProt Accessions	Q58F21, O14789, Q6P5T1, Q7Z4A6, Q8IWI6	Gene names	BRDT
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein).

JIP3_HUMAN
NC score	0.057254 (rank : 577)	θ value	θ > 10 (rank : 619)
Query Neighborhood Hits	451	Target Neighborhood Hits	1039	Shared Neighborhood Hits	129
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

DSPP_HUMAN
NC score	0.057185 (rank : 578)	θ value	θ > 10 (rank : 559)
Query Neighborhood Hits	451	Target Neighborhood Hits	645	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

JIP1_HUMAN
NC score	0.057049 (rank : 579)	θ value	θ > 10 (rank : 617)
Query Neighborhood Hits	451	Target Neighborhood Hits	271	Shared Neighborhood Hits	68
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

R51A1_MOUSE
NC score	0.057028 (rank : 580)	θ value	θ > 10 (rank : 724)
Query Neighborhood Hits	451	Target Neighborhood Hits	164	Shared Neighborhood Hits	26
SwissProt Accessions	Q8C551, O55219, Q8BP36, Q99L94, Q9D0J0	Gene names	Rad51ap1
Domain Architecture	No domain graphic available
Description	RAD51-associated protein 1 (RAD51-interacting protein) (RAB22).

NFAC1_HUMAN
NC score	0.057014 (rank : 581)	θ value	θ > 10 (rank : 673)
Query Neighborhood Hits	451	Target Neighborhood Hits	312	Shared Neighborhood Hits	85
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

PGCA_HUMAN
NC score	0.057006 (rank : 582)	θ value	0.125558 (rank : 108)
Query Neighborhood Hits	451	Target Neighborhood Hits	821	Shared Neighborhood Hits	64
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

MBD5_HUMAN
NC score	0.056822 (rank : 583)	θ value	θ > 10 (rank : 641)
Query Neighborhood Hits	451	Target Neighborhood Hits	176	Shared Neighborhood Hits	43
SwissProt Accessions	Q9P267, Q9NUV6	Gene names	MBD5, KIAA1461
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 5 (Methyl-CpG-binding protein MBD5).

RIMB1_HUMAN
NC score	0.056761 (rank : 584)	θ value	θ > 10 (rank : 735)
Query Neighborhood Hits	451	Target Neighborhood Hits	1479	Shared Neighborhood Hits	134
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

NFM_HUMAN
NC score	0.056721 (rank : 585)	θ value	4.03905 (rank : 338)
Query Neighborhood Hits	451	Target Neighborhood Hits	1328	Shared Neighborhood Hits	125
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

IF4G3_MOUSE
NC score	0.056632 (rank : 586)	θ value	θ > 10 (rank : 610)
Query Neighborhood Hits	451	Target Neighborhood Hits	279	Shared Neighborhood Hits	38
SwissProt Accessions	Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0	Gene names	Eif4g3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

PTN23_MOUSE
NC score	0.056630 (rank : 587)	θ value	θ > 10 (rank : 721)
Query Neighborhood Hits	451	Target Neighborhood Hits	726	Shared Neighborhood Hits	112
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

SCAP_HUMAN
NC score	0.056555 (rank : 588)	θ value	0.163984 (rank : 120)
Query Neighborhood Hits	451	Target Neighborhood Hits	368	Shared Neighborhood Hits	60
SwissProt Accessions	Q12770, Q8N2E0, Q8WUA1	Gene names	SCAP, KIAA0199
Domain Architecture
Description	Sterol regulatory element-binding protein cleavage-activating protein (SREBP cleavage-activating protein) (SCAP).

RCOR2_HUMAN
NC score	0.056540 (rank : 589)	θ value	6.88961 (rank : 404)
Query Neighborhood Hits	451	Target Neighborhood Hits	114	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IZ40, Q96FP3	Gene names	RCOR2
Domain Architecture	No domain graphic available
Description	REST corepressor 2.

MAP2_HUMAN
NC score	0.056420 (rank : 590)	θ value	θ > 10 (rank : 633)
Query Neighborhood Hits	451	Target Neighborhood Hits	348	Shared Neighborhood Hits	58
SwissProt Accessions	P11137, Q99975, Q99976	Gene names	MAP2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2) (MAP-2).

BCAS1_MOUSE
NC score	0.056305 (rank : 591)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	451	Target Neighborhood Hits	215	Shared Neighborhood Hits	39
SwissProt Accessions	Q80YN3, Q9CVA1	Gene names	Bcas1, Nabc1
Domain Architecture	No domain graphic available
Description	Breast carcinoma amplified sequence 1 homolog (Novel amplified in breast cancer 1 homolog).

HCLS1_HUMAN
NC score	0.056278 (rank : 592)	θ value	θ > 10 (rank : 602)
Query Neighborhood Hits	451	Target Neighborhood Hits	358	Shared Neighborhood Hits	83
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

PRGC2_HUMAN
NC score	0.056119 (rank : 593)	θ value	θ > 10 (rank : 713)
Query Neighborhood Hits	451	Target Neighborhood Hits	272	Shared Neighborhood Hits	64
SwissProt Accessions	Q86YN6, Q86YN3, Q86YN4, Q86YN5, Q8N1N9, Q8TDE4, Q8TDE5	Gene names	PPARGC1B, PERC, PGC1, PGC1B, PPARGC1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta) (PGC-1-related estrogen receptor alpha coactivator) (PPARGC-1-beta) (PGC-1-beta).

NELFA_HUMAN
NC score	0.056036 (rank : 594)	θ value	θ > 10 (rank : 669)
Query Neighborhood Hits	451	Target Neighborhood Hits	161	Shared Neighborhood Hits	45
SwissProt Accessions	Q9H3P2, O95392	Gene names	WHSC2, NELFA
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 protein).

SF01_HUMAN
NC score	0.055876 (rank : 595)	θ value	θ > 10 (rank : 763)
Query Neighborhood Hits	451	Target Neighborhood Hits	287	Shared Neighborhood Hits	65
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

PHLB1_MOUSE
NC score	0.055852 (rank : 596)	θ value	θ > 10 (rank : 703)
Query Neighborhood Hits	451	Target Neighborhood Hits	678	Shared Neighborhood Hits	74
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

GNAS3_HUMAN
NC score	0.055842 (rank : 597)	θ value	θ > 10 (rank : 593)
Query Neighborhood Hits	451	Target Neighborhood Hits	71	Shared Neighborhood Hits	18
SwissProt Accessions	O95467, O95417	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Neuroendocrine secretory protein 55 (NESP55) [Contains: LHAL tetrapeptide; GPIPIRRH peptide].

PHLA1_HUMAN
NC score	0.055587 (rank : 598)	θ value	θ > 10 (rank : 702)
Query Neighborhood Hits	451	Target Neighborhood Hits	121	Shared Neighborhood Hits	35
SwissProt Accessions	Q8WV24, Q15184, Q2TAN2, Q9NZ17	Gene names	PHLDA1, PHRIP, TDAG51
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family A member 1 (T-cell death- associated gene 51 protein) (Apoptosis-associated nuclear protein) (Proline- and histidine-rich protein) (Proline- and glutamine-rich protein) (PQ-rich protein).

PO6F1_MOUSE
NC score	0.055574 (rank : 599)	θ value	θ > 10 (rank : 708)
Query Neighborhood Hits	451	Target Neighborhood Hits	581	Shared Neighborhood Hits	90
SwissProt Accessions	Q07916, Q91XK3	Gene names	Pou6f1, Emb
Domain Architecture
Description	POU domain, class 6, transcription factor 1 (Octamer-binding transcription factor EMB) (Transcription regulatory protein MCP-1).

ARHGF_HUMAN
NC score	0.055555 (rank : 600)	θ value	1.06291 (rank : 197)
Query Neighborhood Hits	451	Target Neighborhood Hits	214	Shared Neighborhood Hits	42
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

AF9_HUMAN
NC score	0.055498 (rank : 601)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	451	Target Neighborhood Hits	202	Shared Neighborhood Hits	25
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

MECP2_MOUSE
NC score	0.055468 (rank : 602)	θ value	2.36792 (rank : 276)
Query Neighborhood Hits	451	Target Neighborhood Hits	76	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Z2D6	Gene names	Mecp2
Domain Architecture
Description	Methyl-CpG-binding protein 2 (MeCP-2 protein) (MeCP2).

ASPP2_HUMAN
NC score	0.055439 (rank : 603)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	451	Target Neighborhood Hits	1156	Shared Neighborhood Hits	118
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

ACD_HUMAN
NC score	0.055420 (rank : 604)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	451	Target Neighborhood Hits	143	Shared Neighborhood Hits	36
SwissProt Accessions	Q96AP0, Q562H5, Q9H8F9	Gene names	ACD, PIP1, PTOP
Domain Architecture	No domain graphic available
Description	Adrenocortical dysplasia protein homolog (POT1 and TIN2-interacting protein).

ARI5B_HUMAN
NC score	0.055398 (rank : 605)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	451	Target Neighborhood Hits	328	Shared Neighborhood Hits	56
SwissProt Accessions	Q14865, Q7Z3M4, Q8N421, Q9H786	Gene names	ARID5B, DESRT, MRF2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (Mrf1-like) (Modulator recognition factor 2) (MRF-2).

PDLI7_HUMAN
NC score	0.055291 (rank : 606)	θ value	θ > 10 (rank : 695)
Query Neighborhood Hits	451	Target Neighborhood Hits	547	Shared Neighborhood Hits	112
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

SPEG_HUMAN
NC score	0.055245 (rank : 607)	θ value	0.0330416 (rank : 78)
Query Neighborhood Hits	451	Target Neighborhood Hits	1762	Shared Neighborhood Hits	165
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SGIP1_HUMAN
NC score	0.055158 (rank : 608)	θ value	θ > 10 (rank : 771)
Query Neighborhood Hits	451	Target Neighborhood Hits	198	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

CBL_MOUSE
NC score	0.055117 (rank : 609)	θ value	θ > 10 (rank : 509)
Query Neighborhood Hits	451	Target Neighborhood Hits	426	Shared Neighborhood Hits	79
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

ENAM_HUMAN
NC score	0.055105 (rank : 610)	θ value	θ > 10 (rank : 568)
Query Neighborhood Hits	451	Target Neighborhood Hits	227	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NRM1, Q9H3D1	Gene names	ENAM
Domain Architecture
Description	Enamelin precursor.

BCLF1_HUMAN
NC score	0.055066 (rank : 611)	θ value	θ > 10 (rank : 496)
Query Neighborhood Hits	451	Target Neighborhood Hits	298	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NYF8, Q14673, Q86WU6, Q86WY0	Gene names	BCLAF1, BTF, KIAA0164
Domain Architecture	No domain graphic available
Description	Bcl-2-associated transcription factor 1 (Btf).

MAP2_MOUSE
NC score	0.054847 (rank : 612)	θ value	θ > 10 (rank : 634)
Query Neighborhood Hits	451	Target Neighborhood Hits	342	Shared Neighborhood Hits	61
SwissProt Accessions	P20357	Gene names	Map2, Mtap2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2).

MUCDL_MOUSE
NC score	0.054844 (rank : 613)	θ value	θ > 10 (rank : 660)
Query Neighborhood Hits	451	Target Neighborhood Hits	461	Shared Neighborhood Hits	66
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

3BP1_HUMAN
NC score	0.054818 (rank : 614)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	451	Target Neighborhood Hits	376	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

T2FA_HUMAN
NC score	0.054782 (rank : 615)	θ value	θ > 10 (rank : 799)
Query Neighborhood Hits	451	Target Neighborhood Hits	228	Shared Neighborhood Hits	30
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

CSKI2_HUMAN
NC score	0.054677 (rank : 616)	θ value	θ > 10 (rank : 540)
Query Neighborhood Hits	451	Target Neighborhood Hits	747	Shared Neighborhood Hits	79
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

ARHG7_HUMAN
NC score	0.054603 (rank : 617)	θ value	0.00175202 (rank : 46)
Query Neighborhood Hits	451	Target Neighborhood Hits	347	Shared Neighborhood Hits	21
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

INP5E_MOUSE
NC score	0.054598 (rank : 618)	θ value	2.36792 (rank : 274)
Query Neighborhood Hits	451	Target Neighborhood Hits	59	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JII1, Q3TCC9	Gene names	Inpp5e
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

DNL1_HUMAN
NC score	0.054497 (rank : 619)	θ value	θ > 10 (rank : 555)
Query Neighborhood Hits	451	Target Neighborhood Hits	216	Shared Neighborhood Hits	41
SwissProt Accessions	P18858	Gene names	LIG1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

MAVS_MOUSE
NC score	0.054469 (rank : 620)	θ value	θ > 10 (rank : 639)
Query Neighborhood Hits	451	Target Neighborhood Hits	170	Shared Neighborhood Hits	48
SwissProt Accessions	Q8VCF0	Gene names	Mavs, Ips1, Visa
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif).

AKAP2_MOUSE
NC score	0.054400 (rank : 621)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	451	Target Neighborhood Hits	385	Shared Neighborhood Hits	55
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

ICAL_MOUSE
NC score	0.054384 (rank : 622)	θ value	θ > 10 (rank : 606)
Query Neighborhood Hits	451	Target Neighborhood Hits	178	Shared Neighborhood Hits	24
SwissProt Accessions	P51125, Q9EQV4, Q9EQV5, Q9QXQ3, Q9QXQ4, Q9R0N1	Gene names	Cast
Domain Architecture
Description	Calpastatin (Calpain inhibitor).

SYP2L_HUMAN
NC score	0.054272 (rank : 623)	θ value	θ > 10 (rank : 796)
Query Neighborhood Hits	451	Target Neighborhood Hits	400	Shared Neighborhood Hits	79
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

VASP_MOUSE
NC score	0.054240 (rank : 624)	θ value	θ > 10 (rank : 830)
Query Neighborhood Hits	451	Target Neighborhood Hits	195	Shared Neighborhood Hits	46
SwissProt Accessions	P70460, Q3TAP0, Q3TCD2, Q3U0C2, Q3UDF1, Q91VD2, Q9R214	Gene names	Vasp
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

DPOD3_HUMAN
NC score	0.054175 (rank : 625)	θ value	2.36792 (rank : 270)
Query Neighborhood Hits	451	Target Neighborhood Hits	109	Shared Neighborhood Hits	21
SwissProt Accessions	Q15054	Gene names	POLD3, KIAA0039
Domain Architecture	No domain graphic available
Description	DNA polymerase subunit delta 3 (DNA polymerase subunit delta p66).

CCD55_MOUSE
NC score	0.054038 (rank : 626)	θ value	θ > 10 (rank : 512)
Query Neighborhood Hits	451	Target Neighborhood Hits	519	Shared Neighborhood Hits	52
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

CSKI2_MOUSE
NC score	0.054035 (rank : 627)	θ value	θ > 10 (rank : 541)
Query Neighborhood Hits	451	Target Neighborhood Hits	812	Shared Neighborhood Hits	104
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

MAGD4_HUMAN
NC score	0.053999 (rank : 628)	θ value	θ > 10 (rank : 632)
Query Neighborhood Hits	451	Target Neighborhood Hits	338	Shared Neighborhood Hits	82
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

FXL19_MOUSE
NC score	0.053997 (rank : 629)	θ value	θ > 10 (rank : 576)
Query Neighborhood Hits	451	Target Neighborhood Hits	217	Shared Neighborhood Hits	66
SwissProt Accessions	Q6PB97, Q7TSH0, Q8BIB4	Gene names	Fbxl19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

VASP_HUMAN
NC score	0.053929 (rank : 630)	θ value	θ > 10 (rank : 829)
Query Neighborhood Hits	451	Target Neighborhood Hits	201	Shared Neighborhood Hits	45
SwissProt Accessions	P50552, Q6PIZ1, Q93035	Gene names	VASP
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

MS3L1_MOUSE
NC score	0.053888 (rank : 631)	θ value	0.62314 (rank : 174)
Query Neighborhood Hits	451	Target Neighborhood Hits	67	Shared Neighborhood Hits	13
SwissProt Accessions	Q9WVG9	Gene names	Msl3l1, Msl31
Domain Architecture
Description	Male-specific lethal 3-like 1 (MSL3-like 1) (Male-specific lethal-3 homolog 1).

AMELX_MOUSE
NC score	0.053664 (rank : 632)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	451	Target Neighborhood Hits	58	Shared Neighborhood Hits	14
SwissProt Accessions	P63277, P45559, P70592, Q61293	Gene names	Amelx, Amel
Domain Architecture	No domain graphic available
Description	Amelogenin, X isoform precursor (Leucine-rich amelogenin peptide) (LRAP).

MYCB2_HUMAN
NC score	0.053655 (rank : 633)	θ value	θ > 10 (rank : 662)
Query Neighborhood Hits	451	Target Neighborhood Hits	390	Shared Neighborhood Hits	51
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

SETD8_MOUSE
NC score	0.053566 (rank : 634)	θ value	θ > 10 (rank : 762)
Query Neighborhood Hits	451	Target Neighborhood Hits	131	Shared Neighborhood Hits	33
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).

RFIP1_HUMAN
NC score	0.053444 (rank : 635)	θ value	θ > 10 (rank : 731)
Query Neighborhood Hits	451	Target Neighborhood Hits	236	Shared Neighborhood Hits	43
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

ZN318_MOUSE
NC score	0.053358 (rank : 636)	θ value	θ > 10 (rank : 848)
Query Neighborhood Hits	451	Target Neighborhood Hits	642	Shared Neighborhood Hits	78
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

LEO1_MOUSE
NC score	0.053245 (rank : 637)	θ value	θ > 10 (rank : 628)
Query Neighborhood Hits	451	Target Neighborhood Hits	946	Shared Neighborhood Hits	65
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

YETS2_MOUSE
NC score	0.053130 (rank : 638)	θ value	θ > 10 (rank : 837)
Query Neighborhood Hits	451	Target Neighborhood Hits	278	Shared Neighborhood Hits	47
SwissProt Accessions	Q3TUF7, Q6PGF8, Q80TI2, Q8CG86	Gene names	Yeats2, Kiaa1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

ZAR1_MOUSE
NC score	0.053126 (rank : 639)	θ value	θ > 10 (rank : 841)
Query Neighborhood Hits	451	Target Neighborhood Hits	254	Shared Neighborhood Hits	46
SwissProt Accessions	Q80SU3	Gene names	Zar1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

ZCH11_HUMAN
NC score	0.053073 (rank : 640)	θ value	θ > 10 (rank : 843)
Query Neighborhood Hits	451	Target Neighborhood Hits	278	Shared Neighborhood Hits	64
SwissProt Accessions	Q5TAX3, Q12764, Q5TAX4, Q86XZ3	Gene names	ZCCHC11, KIAA0191
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 11.

ALO17_HUMAN
NC score	0.052955 (rank : 641)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	451	Target Neighborhood Hits	317	Shared Neighborhood Hits	45
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

MILK2_HUMAN
NC score	0.052914 (rank : 642)	θ value	θ > 10 (rank : 649)
Query Neighborhood Hits	451	Target Neighborhood Hits	457	Shared Neighborhood Hits	65
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

RECQ5_HUMAN
NC score	0.052856 (rank : 643)	θ value	θ > 10 (rank : 729)
Query Neighborhood Hits	451	Target Neighborhood Hits	390	Shared Neighborhood Hits	89
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

ARHG7_MOUSE
NC score	0.052837 (rank : 644)	θ value	0.00869519 (rank : 58)
Query Neighborhood Hits	451	Target Neighborhood Hits	396	Shared Neighborhood Hits	20
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

MUC13_MOUSE
NC score	0.052826 (rank : 645)	θ value	θ > 10 (rank : 656)
Query Neighborhood Hits	451	Target Neighborhood Hits	447	Shared Neighborhood Hits	48
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

G3BP2_MOUSE
NC score	0.052669 (rank : 646)	θ value	θ > 10 (rank : 579)
Query Neighborhood Hits	451	Target Neighborhood Hits	258	Shared Neighborhood Hits	33
SwissProt Accessions	P97379, Q9R1B8	Gene names	G3bp2
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 2 (GAP SH3-domain- binding protein 2) (G3BP-2).

DMP1_MOUSE
NC score	0.052617 (rank : 647)	θ value	θ > 10 (rank : 554)
Query Neighborhood Hits	451	Target Neighborhood Hits	498	Shared Neighborhood Hits	32
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

MECP2_HUMAN
NC score	0.052544 (rank : 648)	θ value	θ > 10 (rank : 644)
Query Neighborhood Hits	451	Target Neighborhood Hits	92	Shared Neighborhood Hits	26
SwissProt Accessions	P51608, O15233	Gene names	MECP2
Domain Architecture
Description	Methyl-CpG-binding protein 2 (MeCP-2 protein) (MeCP2).

TACC2_MOUSE
NC score	0.052523 (rank : 649)	θ value	θ > 10 (rank : 802)
Query Neighborhood Hits	451	Target Neighborhood Hits	774	Shared Neighborhood Hits	82
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

SYNJ2_MOUSE
NC score	0.052467 (rank : 650)	θ value	θ > 10 (rank : 793)
Query Neighborhood Hits	451	Target Neighborhood Hits	87	Shared Neighborhood Hits	22
SwissProt Accessions	Q9D2G5, O35404, O88399, O88400, O88401, O88402, O88403, O88404	Gene names	Synj2, Kiaa0348
Domain Architecture
Description	Synaptojanin-2 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 2).

RU1C_HUMAN
NC score	0.052456 (rank : 651)	θ value	θ > 10 (rank : 748)
Query Neighborhood Hits	451	Target Neighborhood Hits	81	Shared Neighborhood Hits	20
SwissProt Accessions	P09234	Gene names	SNRPC
Domain Architecture
Description	U1 small nuclear ribonucleoprotein C (U1 snRNP protein C) (U1C protein) (U1-C).

RANB3_HUMAN
NC score	0.052432 (rank : 652)	θ value	1.81305 (rank : 259)
Query Neighborhood Hits	451	Target Neighborhood Hits	117	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H6Z4, O60405, O75759, O75760, Q9BT47, Q9UG74	Gene names	RANBP3
Domain Architecture	No domain graphic available
Description	Ran-binding protein 3 (RanBP3).

MDN1_HUMAN
NC score	0.052409 (rank : 653)	θ value	θ > 10 (rank : 643)
Query Neighborhood Hits	451	Target Neighborhood Hits	662	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

BAZ1A_HUMAN
NC score	0.052319 (rank : 654)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	451	Target Neighborhood Hits	693	Shared Neighborhood Hits	55
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

TCF20_MOUSE
NC score	0.052152 (rank : 655)	θ value	θ > 10 (rank : 809)
Query Neighborhood Hits	451	Target Neighborhood Hits	396	Shared Neighborhood Hits	60
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

RCOR3_HUMAN
NC score	0.052120 (rank : 656)	θ value	8.99809 (rank : 437)
Query Neighborhood Hits	451	Target Neighborhood Hits	161	Shared Neighborhood Hits	37
SwissProt Accessions	Q9P2K3, Q5VT47, Q7L9I5, Q8N5U3, Q9NV83	Gene names	RCOR3, KIAA1343
Domain Architecture	No domain graphic available
Description	REST corepressor 3.

AHTF1_MOUSE
NC score	0.052108 (rank : 657)	θ value	6.88961 (rank : 388)
Query Neighborhood Hits	451	Target Neighborhood Hits	176	Shared Neighborhood Hits	41
SwissProt Accessions	Q8CJF7, Q8BVJ5, Q8VD55	Gene names	Ahctf1, Elys
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

PDC6I_HUMAN
NC score	0.052090 (rank : 658)	θ value	θ > 10 (rank : 694)
Query Neighborhood Hits	451	Target Neighborhood Hits	278	Shared Neighborhood Hits	54
SwissProt Accessions	Q8WUM4, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5	Gene names	PDCD6IP, AIP1, ALIX, KIAA1375
Domain Architecture
Description	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95).

RFX1_HUMAN
NC score	0.052042 (rank : 659)	θ value	θ > 10 (rank : 732)
Query Neighborhood Hits	451	Target Neighborhood Hits	256	Shared Neighborhood Hits	69
SwissProt Accessions	P22670	Gene names	RFX1
Domain Architecture
Description	MHC class II regulatory factor RFX1 (RFX) (Enhancer factor C) (EF-C).

TCAL5_HUMAN
NC score	0.051950 (rank : 660)	θ value	θ > 10 (rank : 808)
Query Neighborhood Hits	451	Target Neighborhood Hits	806	Shared Neighborhood Hits	72
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

DSPP_MOUSE
NC score	0.051814 (rank : 661)	θ value	θ > 10 (rank : 560)
Query Neighborhood Hits	451	Target Neighborhood Hits	491	Shared Neighborhood Hits	38
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

SF01_MOUSE
NC score	0.051792 (rank : 662)	θ value	θ > 10 (rank : 764)
Query Neighborhood Hits	451	Target Neighborhood Hits	240	Shared Neighborhood Hits	58
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

TULP4_MOUSE
NC score	0.051671 (rank : 663)	θ value	θ > 10 (rank : 825)
Query Neighborhood Hits	451	Target Neighborhood Hits	247	Shared Neighborhood Hits	48
SwissProt Accessions	Q9JIL5, Q8CA75, Q922C2	Gene names	Tulp4, Tusp
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

TAB3_MOUSE
NC score	0.051640 (rank : 664)	θ value	θ > 10 (rank : 800)
Query Neighborhood Hits	451	Target Neighborhood Hits	273	Shared Neighborhood Hits	67
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

RP3A_MOUSE
NC score	0.051606 (rank : 665)	θ value	θ > 10 (rank : 739)
Query Neighborhood Hits	451	Target Neighborhood Hits	510	Shared Neighborhood Hits	105
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

RPTN_MOUSE
NC score	0.051598 (rank : 666)	θ value	θ > 10 (rank : 743)
Query Neighborhood Hits	451	Target Neighborhood Hits	650	Shared Neighborhood Hits	71
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

SPR2D_MOUSE
NC score	0.051523 (rank : 667)	θ value	θ > 10 (rank : 782)
Query Neighborhood Hits	451	Target Neighborhood Hits	61	Shared Neighborhood Hits	14
SwissProt Accessions	O70555	Gene names	Sprr2d
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D.

RIMS3_MOUSE
NC score	0.051467 (rank : 668)	θ value	θ > 10 (rank : 737)
Query Neighborhood Hits	451	Target Neighborhood Hits	67	Shared Neighborhood Hits	7
SwissProt Accessions	Q80U57	Gene names	Rims3, Kiaa0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

IQEC3_MOUSE
NC score	0.051395 (rank : 669)	θ value	θ > 10 (rank : 614)
Query Neighborhood Hits	451	Target Neighborhood Hits	274	Shared Neighborhood Hits	53
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

PYGO2_HUMAN
NC score	0.051394 (rank : 670)	θ value	θ > 10 (rank : 722)
Query Neighborhood Hits	451	Target Neighborhood Hits	189	Shared Neighborhood Hits	50
SwissProt Accessions	Q9BRQ0, Q8WYZ4, Q96CY2	Gene names	PYGO2
Domain Architecture
Description	Pygopus homolog 2.

G3BP2_HUMAN
NC score	0.051342 (rank : 671)	θ value	θ > 10 (rank : 578)
Query Neighborhood Hits	451	Target Neighborhood Hits	260	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UN86, O60606, O75149, Q9UPA1	Gene names	G3BP2, KIAA0660
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 2 (GAP SH3-domain- binding protein 2) (G3BP-2).

GPS2_HUMAN
NC score	0.051303 (rank : 672)	θ value	θ > 10 (rank : 596)
Query Neighborhood Hits	451	Target Neighborhood Hits	459	Shared Neighborhood Hits	53
SwissProt Accessions	Q13227	Gene names	GPS2
Domain Architecture	No domain graphic available
Description	G protein pathway suppressor 2 (Protein GPS2).

ZCHC5_HUMAN
NC score	0.051171 (rank : 673)	θ value	θ > 10 (rank : 844)
Query Neighborhood Hits	451	Target Neighborhood Hits	75	Shared Neighborhood Hits	18
SwissProt Accessions	Q8N8U3	Gene names	ZCCHC5
Domain Architecture
Description	Zinc finger CCHC domain-containing protein 5.

ABI3_HUMAN
NC score	0.051022 (rank : 674)	θ value	8.99809 (rank : 408)
Query Neighborhood Hits	451	Target Neighborhood Hits	227	Shared Neighborhood Hits	37
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

DREB_MOUSE
NC score	0.050939 (rank : 675)	θ value	1.06291 (rank : 203)
Query Neighborhood Hits	451	Target Neighborhood Hits	446	Shared Neighborhood Hits	38
SwissProt Accessions	Q9QXS6, Q922X1, Q9QXS5	Gene names	Dbn1, Drba
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

DMP1_HUMAN
NC score	0.050884 (rank : 676)	θ value	θ > 10 (rank : 553)
Query Neighborhood Hits	451	Target Neighborhood Hits	491	Shared Neighborhood Hits	33
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

WNK2_HUMAN
NC score	0.050804 (rank : 677)	θ value	1.38821 (rank : 241)
Query Neighborhood Hits	451	Target Neighborhood Hits	1407	Shared Neighborhood Hits	157
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

BTBDC_HUMAN
NC score	0.050796 (rank : 678)	θ value	θ > 10 (rank : 506)
Query Neighborhood Hits	451	Target Neighborhood Hits	248	Shared Neighborhood Hits	57
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

RIMS3_HUMAN
NC score	0.050667 (rank : 679)	θ value	θ > 10 (rank : 736)
Query Neighborhood Hits	451	Target Neighborhood Hits	66	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UJD0, Q92511	Gene names	RIMS3, KIAA0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

RPGF1_HUMAN
NC score	0.050565 (rank : 680)	θ value	θ > 10 (rank : 742)
Query Neighborhood Hits	451	Target Neighborhood Hits	262	Shared Neighborhood Hits	75
SwissProt Accessions	Q13905	Gene names	RAPGEF1, GRF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP).

PODXL_HUMAN
NC score	0.050422 (rank : 681)	θ value	θ > 10 (rank : 709)
Query Neighborhood Hits	451	Target Neighborhood Hits	191	Shared Neighborhood Hits	26
SwissProt Accessions	O00592	Gene names	PODXL, PCLP, PCLP1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

FA53C_HUMAN
NC score	0.050402 (rank : 682)	θ value	1.81305 (rank : 249)
Query Neighborhood Hits	451	Target Neighborhood Hits	29	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NYF3	Gene names	FAM53C, C5orf6
Domain Architecture	No domain graphic available
Description	Protein FAM53C.

CP007_MOUSE
NC score	0.050181 (rank : 683)	θ value	θ > 10 (rank : 531)
Query Neighborhood Hits	451	Target Neighborhood Hits	231	Shared Neighborhood Hits	49
SwissProt Accessions	Q8C190, Q6PFD1	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf7 homolog (5-day ovary-specific transcript 1 protein).

MYPN_MOUSE
NC score	0.050002 (rank : 684)	θ value	1.06291 (rank : 209)
Query Neighborhood Hits	451	Target Neighborhood Hits	421	Shared Neighborhood Hits	25
SwissProt Accessions	Q5DTJ9, Q7TPW5, Q8BZ76	Gene names	Mypn, Kiaa4170
Domain Architecture	No domain graphic available
Description	Myopalladin.

MS3L1_HUMAN
NC score	0.049979 (rank : 685)	θ value	2.36792 (rank : 278)
Query Neighborhood Hits	451	Target Neighborhood Hits	60	Shared Neighborhood Hits	13
SwissProt Accessions	Q8N5Y2, Q9UG70, Q9Y5Z8	Gene names	MSL3L1
Domain Architecture
Description	Male-specific lethal 3-like 1 (MSL3-like 1) (Male-specific lethal-3 homolog 1).

DNMT1_MOUSE
NC score	0.049313 (rank : 686)	θ value	1.06291 (rank : 202)
Query Neighborhood Hits	451	Target Neighborhood Hits	137	Shared Neighborhood Hits	19
SwissProt Accessions	P13864, P97413, Q80ZU3, Q9CSC6, Q9QXX6	Gene names	Dnmt1, Dnmt, Met1, Uim
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase MmuI) (DNA MTase MmuI) (MCMT) (M.MmuI) (Met-1).

FA21C_HUMAN
NC score	0.049296 (rank : 687)	θ value	8.99809 (rank : 420)
Query Neighborhood Hits	451	Target Neighborhood Hits	194	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y4E1, Q5SQU4, Q5SQU5, Q7L521, Q9UG79	Gene names	FAM21C, KIAA0592
Domain Architecture	No domain graphic available
Description	Protein FAM21C.

ETV5_MOUSE
NC score	0.048990 (rank : 688)	θ value	3.0926 (rank : 296)
Query Neighborhood Hits	451	Target Neighborhood Hits	328	Shared Neighborhood Hits	83
SwissProt Accessions	Q9CXC9, Q3TG49, Q8C0F3, Q9JHB1	Gene names	Etv5
Domain Architecture	No domain graphic available
Description	ETS translocation variant 5.

AIPL1_HUMAN
NC score	0.047973 (rank : 689)	θ value	0.47712 (rank : 159)
Query Neighborhood Hits	451	Target Neighborhood Hits	113	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NZN9, Q9H873, Q9NS10	Gene names	AIPL1
Domain Architecture
Description	Aryl-hydrocarbon-interacting protein-like 1.

CDT1_MOUSE
NC score	0.047796 (rank : 690)	θ value	4.03905 (rank : 328)
Query Neighborhood Hits	451	Target Neighborhood Hits	72	Shared Neighborhood Hits	19
SwissProt Accessions	Q8R4E9, Q8BUQ1, Q8BX29, Q8R3V0, Q8R4E8	Gene names	Cdt1, Ris2
Domain Architecture	No domain graphic available
Description	DNA replication factor Cdt1 (Double parked homolog) (DUP) (Retroviral insertion site 2 protein).

3BP2_MOUSE
NC score	0.046971 (rank : 691)	θ value	5.27518 (rank : 349)
Query Neighborhood Hits	451	Target Neighborhood Hits	142	Shared Neighborhood Hits	24
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

SMN_HUMAN
NC score	0.045423 (rank : 692)	θ value	5.27518 (rank : 376)
Query Neighborhood Hits	451	Target Neighborhood Hits	39	Shared Neighborhood Hits	11
SwissProt Accessions	Q16637, Q13119, Q96J51	Gene names	SMN1, SMN, SMNT
Domain Architecture
Description	Survival motor neuron protein (Component of gems 1) (Gemin-1).

MEGF9_HUMAN
NC score	0.045240 (rank : 693)	θ value	1.38821 (rank : 234)
Query Neighborhood Hits	451	Target Neighborhood Hits	557	Shared Neighborhood Hits	53
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

IL4RA_HUMAN
NC score	0.045044 (rank : 694)	θ value	3.0926 (rank : 298)
Query Neighborhood Hits	451	Target Neighborhood Hits	144	Shared Neighborhood Hits	32
SwissProt Accessions	P24394, Q96P01, Q9H181, Q9H182, Q9H183, Q9H184, Q9H185, Q9H186, Q9H187, Q9H188	Gene names	IL4R, 582J2.1, IL4RA
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (sIL4Ralpha/prot) (IL-4-binding protein) (IL4-BP)].

IRS1_MOUSE
NC score	0.044558 (rank : 695)	θ value	1.06291 (rank : 208)
Query Neighborhood Hits	451	Target Neighborhood Hits	112	Shared Neighborhood Hits	23
SwissProt Accessions	P35569	Gene names	Irs1, Irs-1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

HXA3_MOUSE
NC score	0.043429 (rank : 696)	θ value	1.81305 (rank : 253)
Query Neighborhood Hits	451	Target Neighborhood Hits	558	Shared Neighborhood Hits	71
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

TTBK1_HUMAN
NC score	0.042894 (rank : 697)	θ value	0.163984 (rank : 121)
Query Neighborhood Hits	451	Target Neighborhood Hits	1058	Shared Neighborhood Hits	97
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

AIRE_MOUSE
NC score	0.042863 (rank : 698)	θ value	8.99809 (rank : 409)
Query Neighborhood Hits	451	Target Neighborhood Hits	196	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

MYCB2_MOUSE
NC score	0.041676 (rank : 699)	θ value	2.36792 (rank : 279)
Query Neighborhood Hits	451	Target Neighborhood Hits	307	Shared Neighborhood Hits	33
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

SH3K1_HUMAN
NC score	0.041473 (rank : 700)	θ value	1.06291 (rank : 216)
Query Neighborhood Hits	451	Target Neighborhood Hits	341	Shared Neighborhood Hits	32
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

HSF1_HUMAN
NC score	0.041400 (rank : 701)	θ value	2.36792 (rank : 273)
Query Neighborhood Hits	451	Target Neighborhood Hits	163	Shared Neighborhood Hits	37
SwissProt Accessions	Q00613	Gene names	HSF1, HSTF1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

SMN_MOUSE
NC score	0.041379 (rank : 702)	θ value	3.0926 (rank : 319)
Query Neighborhood Hits	451	Target Neighborhood Hits	29	Shared Neighborhood Hits	8
SwissProt Accessions	P97801, O09092	Gene names	Smn1, Smn
Domain Architecture
Description	Survival motor neuron protein.

ZF106_MOUSE
NC score	0.041219 (rank : 703)	θ value	0.365318 (rank : 158)
Query Neighborhood Hits	451	Target Neighborhood Hits	472	Shared Neighborhood Hits	43
SwissProt Accessions	O88466, O55185, O88465, O88467, Q792M1, Q792P4, Q8CDZ8, Q8R3I4, Q9ESU3	Gene names	Zfp106, H3a, Sh3bp3, Sirm, Znf474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 (Zfp-106) (Zinc finger protein 474) (H3a minor histocompatibility antigen) (Son of insulin receptor mutant).

DLGP4_HUMAN
NC score	0.040746 (rank : 704)	θ value	0.21417 (rank : 124)
Query Neighborhood Hits	451	Target Neighborhood Hits	90	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y2H0, Q5T2Y4, Q5T2Y5, Q9H137, Q9H138, Q9H1L7	Gene names	DLGAP4, DAP4, KIAA0964
Domain Architecture
Description	Disks large-associated protein 4 (DAP-4) (SAP90/PSD-95-associated protein 4) (SAPAP4) (PSD-95/SAP90-binding protein 4).

H10_HUMAN
NC score	0.039360 (rank : 705)	θ value	6.88961 (rank : 398)
Query Neighborhood Hits	451	Target Neighborhood Hits	53	Shared Neighborhood Hits	15
SwissProt Accessions	P07305	Gene names	H1F0, H1FV
Domain Architecture
Description	Histone H1.0 (H1(0)) (Histone H1').

SOS1_HUMAN
NC score	0.039082 (rank : 706)	θ value	2.36792 (rank : 283)
Query Neighborhood Hits	451	Target Neighborhood Hits	274	Shared Neighborhood Hits	39
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

SPN90_MOUSE
NC score	0.038904 (rank : 707)	θ value	2.36792 (rank : 284)
Query Neighborhood Hits	451	Target Neighborhood Hits	157	Shared Neighborhood Hits	16
SwissProt Accessions	Q9ESJ4, Q68G72	Gene names	Nckipsd, Spin90, Wasbp
Domain Architecture	No domain graphic available
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (N-WASP-interacting protein, 90kDa) (Wiskott-Aldrich syndrome protein-binding protein WISH) (N-WASP-binding protein).

PCGF4_MOUSE
NC score	0.038788 (rank : 708)	θ value	0.21417 (rank : 130)
Query Neighborhood Hits	451	Target Neighborhood Hits	163	Shared Neighborhood Hits	4
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

SOS1_MOUSE
NC score	0.038740 (rank : 709)	θ value	5.27518 (rank : 378)
Query Neighborhood Hits	451	Target Neighborhood Hits	281	Shared Neighborhood Hits	42
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

ZEP2_HUMAN
NC score	0.038509 (rank : 710)	θ value	0.163984 (rank : 122)
Query Neighborhood Hits	451	Target Neighborhood Hits	937	Shared Neighborhood Hits	73
SwissProt Accessions	P31629, Q02646, Q5THT5, Q9NS05	Gene names	HIVEP2
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 (HIV- EP2) (MHC-binding protein 2) (MBP-2).

JARD2_HUMAN
NC score	0.038329 (rank : 711)	θ value	0.47712 (rank : 165)
Query Neighborhood Hits	451	Target Neighborhood Hits	119	Shared Neighborhood Hits	21
SwissProt Accessions	Q92833, Q5U5L5	Gene names	JARID2, JMJ
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

HXA3_HUMAN
NC score	0.038302 (rank : 712)	θ value	0.813845 (rank : 189)
Query Neighborhood Hits	451	Target Neighborhood Hits	535	Shared Neighborhood Hits	66
SwissProt Accessions	O43365	Gene names	HOXA3, HOX1E
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1E).

BAI1_HUMAN
NC score	0.038166 (rank : 713)	θ value	1.38821 (rank : 226)
Query Neighborhood Hits	451	Target Neighborhood Hits	375	Shared Neighborhood Hits	60
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

SH3K1_MOUSE
NC score	0.037481 (rank : 714)	θ value	3.0926 (rank : 316)
Query Neighborhood Hits	451	Target Neighborhood Hits	332	Shared Neighborhood Hits	35
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

TOP1_MOUSE
NC score	0.037117 (rank : 715)	θ value	3.0926 (rank : 324)
Query Neighborhood Hits	451	Target Neighborhood Hits	213	Shared Neighborhood Hits	24
SwissProt Accessions	Q04750	Gene names	Top1, Top-1
Domain Architecture
Description	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I).

TF3C2_MOUSE
NC score	0.037035 (rank : 716)	θ value	3.0926 (rank : 322)
Query Neighborhood Hits	451	Target Neighborhood Hits	165	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BL74, Q3U7Z9, Q80XQ7, Q8BJJ4, Q8BLP3, Q8K1J1, Q9CSS0, Q9CVE6, Q9DBK6	Gene names	Gtf3c2, Kiaa0011
Domain Architecture
Description	General transcription factor 3C polypeptide 2 (Transcription factor IIIC-subunit beta) (TF3C-beta) (TFIIIC 110 kDa subunit) (TFIIIC110).

WDR46_HUMAN
NC score	0.036944 (rank : 717)	θ value	1.38821 (rank : 240)
Query Neighborhood Hits	451	Target Neighborhood Hits	147	Shared Neighborhood Hits	16
SwissProt Accessions	O15213, Q5STK5	Gene names	WDR46, BING4, C6orf11
Domain Architecture
Description	WD repeat protein 46 (WD repeat protein BING4).

TOP2A_HUMAN
NC score	0.036929 (rank : 718)	θ value	0.62314 (rank : 178)
Query Neighborhood Hits	451	Target Neighborhood Hits	135	Shared Neighborhood Hits	17
SwissProt Accessions	P11388, Q71UN1, Q9HB24, Q9HB25, Q9HB26, Q9UP44, Q9UQP9	Gene names	TOP2A, TOP2
Domain Architecture
Description	DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme).

PC11Y_HUMAN
NC score	0.035456 (rank : 719)	θ value	0.0736092 (rank : 94)
Query Neighborhood Hits	451	Target Neighborhood Hits	205	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BZA8, Q70LR6, Q70LR8, Q70LS0, Q70LS1, Q70LS2, Q70LS3, Q70LS4, Q70LS5, Q8WY34, Q9BZA9, Q9H4E1	Gene names	PCDH11Y, PCDH11, PCDH22, PCDHY
Domain Architecture	No domain graphic available
Description	Protocadherin-11 Y-linked precursor (Protocadherin-11) (Protocadherin- 22) (Protocadherin on the Y chromosome) (PCDH-Y) (Protocadherin prostate cancer) (Protocadherin-PC).

PC11X_HUMAN
NC score	0.035333 (rank : 720)	θ value	0.0330416 (rank : 75)
Query Neighborhood Hits	451	Target Neighborhood Hits	199	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BZA7, Q2TJH0, Q2TJH1, Q2TJH3, Q5JVZ0, Q70LR8, Q70LS7, Q70LS8, Q70LS9, Q70LT7, Q70LT8, Q70LT9, Q70LU0, Q70LU1, Q96RV4, Q96RW0, Q9BZA6, Q9H4E0, Q9P2M0, Q9P2X5	Gene names	PCDH11X, PCDH11, PCDHX
Domain Architecture	No domain graphic available
Description	Protocadherin-11 X-linked precursor (Protocadherin-11) (Protocadherin on the X chromosome) (PCDH-X) (Protocadherin-S).

PCNT_HUMAN
NC score	0.035139 (rank : 721)	θ value	0.813845 (rank : 192)
Query Neighborhood Hits	451	Target Neighborhood Hits	1551	Shared Neighborhood Hits	88
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

BAI1_MOUSE
NC score	0.034520 (rank : 722)	θ value	0.813845 (rank : 182)
Query Neighborhood Hits	451	Target Neighborhood Hits	340	Shared Neighborhood Hits	50
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

DLG5_HUMAN
NC score	0.034137 (rank : 723)	θ value	6.88961 (rank : 392)
Query Neighborhood Hits	451	Target Neighborhood Hits	1088	Shared Neighborhood Hits	92
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

UBN1_HUMAN
NC score	0.034055 (rank : 724)	θ value	8.99809 (rank : 446)
Query Neighborhood Hits	451	Target Neighborhood Hits	170	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NPG3, Q13079, Q9P1P7	Gene names	UBN1
Domain Architecture	No domain graphic available
Description	Ubinuclein (Ubiquitously expressed nuclear protein) (VT4).

AATK_HUMAN
NC score	0.034026 (rank : 725)	θ value	3.0926 (rank : 289)
Query Neighborhood Hits	451	Target Neighborhood Hits	1243	Shared Neighborhood Hits	147
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

SCEL_MOUSE
NC score	0.033271 (rank : 726)	θ value	1.06291 (rank : 215)
Query Neighborhood Hits	451	Target Neighborhood Hits	89	Shared Neighborhood Hits	12
SwissProt Accessions	Q9EQG3, Q9CTT9	Gene names	Scel
Domain Architecture
Description	Sciellin.

USH1C_MOUSE
NC score	0.033198 (rank : 727)	θ value	4.03905 (rank : 347)
Query Neighborhood Hits	451	Target Neighborhood Hits	557	Shared Neighborhood Hits	46
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

K1914_MOUSE
NC score	0.033084 (rank : 728)	θ value	8.99809 (rank : 426)
Query Neighborhood Hits	451	Target Neighborhood Hits	216	Shared Neighborhood Hits	35
SwissProt Accessions	Q5DTU0, Q8BID1, Q8K2G0	Gene names	Kiaa1914
Domain Architecture	No domain graphic available
Description	Protein KIAA1914.

PCGF4_HUMAN
NC score	0.032999 (rank : 729)	θ value	1.06291 (rank : 210)
Query Neighborhood Hits	451	Target Neighborhood Hits	161	Shared Neighborhood Hits	3
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

ELL_MOUSE
NC score	0.032994 (rank : 730)	θ value	3.0926 (rank : 295)
Query Neighborhood Hits	451	Target Neighborhood Hits	115	Shared Neighborhood Hits	27
SwissProt Accessions	O08856	Gene names	Ell
Domain Architecture
Description	RNA polymerase II elongation factor ELL (Eleven-nineteen lysine-rich leukemia protein).

PCD15_MOUSE
NC score	0.032460 (rank : 731)	θ value	0.47712 (rank : 166)
Query Neighborhood Hits	451	Target Neighborhood Hits	262	Shared Neighborhood Hits	40
SwissProt Accessions	Q99PJ1	Gene names	Pcdh15
Domain Architecture
Description	Protocadherin-15 precursor.

GRB10_MOUSE
NC score	0.032223 (rank : 732)	θ value	6.88961 (rank : 397)
Query Neighborhood Hits	451	Target Neighborhood Hits	156	Shared Neighborhood Hits	8
SwissProt Accessions	Q60760, O35352, Q7TSA4, Q8BSH4, Q8BSS5, Q91WC5	Gene names	Grb10
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein).

FIBB_MOUSE
NC score	0.031239 (rank : 733)	θ value	0.0736092 (rank : 93)
Query Neighborhood Hits	451	Target Neighborhood Hits	96	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K0E8, Q91ZP1	Gene names	Fgb
Domain Architecture	No domain graphic available
Description	Fibrinogen beta chain precursor [Contains: Fibrinopeptide B].

GNDS_MOUSE
NC score	0.030716 (rank : 734)	θ value	6.88961 (rank : 394)
Query Neighborhood Hits	451	Target Neighborhood Hits	115	Shared Neighborhood Hits	27
SwissProt Accessions	Q03385	Gene names	Ralgds, Rgds
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator (RalGEF) (RalGDS).

BBX_HUMAN
NC score	0.030620 (rank : 735)	θ value	0.47712 (rank : 160)
Query Neighborhood Hits	451	Target Neighborhood Hits	167	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WY36, Q2TAJ1, Q7L3J8, Q7LBY8, Q8NDB0, Q8WY35, Q9H0J6	Gene names	BBX, HBP2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

ELOA1_MOUSE
NC score	0.030488 (rank : 736)	θ value	8.99809 (rank : 419)
Query Neighborhood Hits	451	Target Neighborhood Hits	152	Shared Neighborhood Hits	25
SwissProt Accessions	Q8CB77, Q80VB2, Q9R0Q5	Gene names	Tceb3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

CEND3_HUMAN
NC score	0.030411 (rank : 737)	θ value	0.813845 (rank : 185)
Query Neighborhood Hits	451	Target Neighborhood Hits	275	Shared Neighborhood Hits	39
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

CD2L7_HUMAN
NC score	0.029589 (rank : 738)	θ value	4.03905 (rank : 327)
Query Neighborhood Hits	451	Target Neighborhood Hits	1275	Shared Neighborhood Hits	120
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

PCD15_HUMAN
NC score	0.029536 (rank : 739)	θ value	2.36792 (rank : 281)
Query Neighborhood Hits	451	Target Neighborhood Hits	289	Shared Neighborhood Hits	37
SwissProt Accessions	Q96QU1, Q96QT8	Gene names	PCDH15
Domain Architecture
Description	Protocadherin-15 precursor.

UBP21_MOUSE
NC score	0.029271 (rank : 740)	θ value	0.21417 (rank : 134)
Query Neighborhood Hits	451	Target Neighborhood Hits	101	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QZL6, Q9D0R1	Gene names	Usp21, Usp23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21).

IQEC3_HUMAN
NC score	0.029001 (rank : 741)	θ value	5.27518 (rank : 365)
Query Neighborhood Hits	451	Target Neighborhood Hits	125	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UPP2, Q8TB43	Gene names	IQSEC3, KIAA1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

SNPH_HUMAN
NC score	0.028752 (rank : 742)	θ value	5.27518 (rank : 377)
Query Neighborhood Hits	451	Target Neighborhood Hits	236	Shared Neighborhood Hits	27
SwissProt Accessions	O15079	Gene names	SNPH, KIAA0374
Domain Architecture	No domain graphic available
Description	Syntaphilin.

GPR64_HUMAN
NC score	0.028523 (rank : 743)	θ value	6.88961 (rank : 396)
Query Neighborhood Hits	451	Target Neighborhood Hits	207	Shared Neighborhood Hits	32
SwissProt Accessions	Q8IZP9, O00406, Q8IWT2, Q8IZE4, Q8IZE5, Q8IZE6, Q8IZE7, Q8IZP3, Q8IZP4	Gene names	GPR64, HE6, TM7LN2
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (He6 receptor).

PLCB1_HUMAN
NC score	0.028142 (rank : 744)	θ value	8.99809 (rank : 434)
Query Neighborhood Hits	451	Target Neighborhood Hits	614	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NQ66, O60325, Q5TFF7, Q5TGC9, Q8IV93, Q9BQW2, Q9H4H2, Q9H8H5, Q9NQ65, Q9NQH9, Q9NTH4, Q9UJP6, Q9UM26	Gene names	PLCB1, KIAA0581
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

TCF19_MOUSE
NC score	0.027720 (rank : 745)	θ value	3.0926 (rank : 321)
Query Neighborhood Hits	451	Target Neighborhood Hits	27	Shared Neighborhood Hits	5
SwissProt Accessions	Q99KJ5, Q8BPA3, Q9CT93	Gene names	Tcf19, Sc1
Domain Architecture
Description	Transcription factor 19-like protein (SC1 protein homolog).

HXB4_HUMAN
NC score	0.026984 (rank : 746)	θ value	0.365318 (rank : 149)
Query Neighborhood Hits	451	Target Neighborhood Hits	376	Shared Neighborhood Hits	24
SwissProt Accessions	P17483, Q9NTA0	Gene names	HOXB4, HOX2F
Domain Architecture
Description	Homeobox protein Hox-B4 (Hox-2F) (Hox-2.6).

PABP3_HUMAN
NC score	0.026644 (rank : 747)	θ value	0.62314 (rank : 175)
Query Neighborhood Hits	451	Target Neighborhood Hits	259	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H361, Q8NHV0, Q9H086	Gene names	PABPC3, PABP3, PABPL3
Domain Architecture
Description	Polyadenylate-binding protein 3 (Poly(A)-binding protein 3) (PABP 3) (Testis-specific poly(A)-binding protein).

PHF13_MOUSE
NC score	0.026461 (rank : 748)	θ value	5.27518 (rank : 371)
Query Neighborhood Hits	451	Target Neighborhood Hits	42	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K2W6	Gene names	Phf13
Domain Architecture
Description	PHD finger protein 13.

ST5_HUMAN
NC score	0.026391 (rank : 749)	θ value	8.99809 (rank : 442)
Query Neighborhood Hits	451	Target Neighborhood Hits	151	Shared Neighborhood Hits	35
SwissProt Accessions	P78524, P78523, Q16492, Q7KYY2, Q7KZ12, Q8NE12, Q9BQQ6	Gene names	ST5, DENND2B, HTS1
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (HeLa tumor suppression 1) (DENN domain-containing protein 2B).

SOX9_HUMAN
NC score	0.026176 (rank : 750)	θ value	4.03905 (rank : 345)
Query Neighborhood Hits	451	Target Neighborhood Hits	210	Shared Neighborhood Hits	46
SwissProt Accessions	P48436	Gene names	SOX9
Domain Architecture
Description	Transcription factor SOX-9.

AZI1_HUMAN
NC score	0.025906 (rank : 751)	θ value	8.99809 (rank : 411)
Query Neighborhood Hits	451	Target Neighborhood Hits	1000	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

H11_HUMAN
NC score	0.025686 (rank : 752)	θ value	8.99809 (rank : 424)
Query Neighborhood Hits	451	Target Neighborhood Hits	51	Shared Neighborhood Hits	13
SwissProt Accessions	Q02539	Gene names	HIST1H1A, H1F1
Domain Architecture
Description	Histone H1.1.

SREC2_MOUSE
NC score	0.025507 (rank : 753)	θ value	3.0926 (rank : 320)
Query Neighborhood Hits	451	Target Neighborhood Hits	605	Shared Neighborhood Hits	45
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

WNK4_HUMAN
NC score	0.025452 (rank : 754)	θ value	8.99809 (rank : 448)
Query Neighborhood Hits	451	Target Neighborhood Hits	1043	Shared Neighborhood Hits	87
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

SMC3_MOUSE
NC score	0.025443 (rank : 755)	θ value	3.0926 (rank : 318)
Query Neighborhood Hits	451	Target Neighborhood Hits	1187	Shared Neighborhood Hits	61
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

SFRS2_HUMAN
NC score	0.025320 (rank : 756)	θ value	4.03905 (rank : 343)
Query Neighborhood Hits	451	Target Neighborhood Hits	222	Shared Neighborhood Hits	19
SwissProt Accessions	Q01130	Gene names	SFRS2
Domain Architecture
Description	Splicing factor, arginine/serine-rich 2 (Splicing factor SC35) (SC-35) (Splicing component, 35 kDa) (Protein PR264).

SFRS2_MOUSE
NC score	0.025320 (rank : 757)	θ value	4.03905 (rank : 344)
Query Neighborhood Hits	451	Target Neighborhood Hits	222	Shared Neighborhood Hits	19
SwissProt Accessions	Q62093, Q542L3, Q60701	Gene names	Sfrs2, Pr264, Sfrs10
Domain Architecture
Description	Splicing factor, arginine/serine-rich 2 (Splicing factor SC35) (SC-35) (Splicing component, 35 kDa) (Protein PR264) (Putative myelin regulatory factor 1) (MRF-1).

SMC3_HUMAN
NC score	0.025290 (rank : 758)	θ value	3.0926 (rank : 317)
Query Neighborhood Hits	451	Target Neighborhood Hits	1186	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

EMIL2_MOUSE
NC score	0.024811 (rank : 759)	θ value	4.03905 (rank : 330)
Query Neighborhood Hits	451	Target Neighborhood Hits	485	Shared Neighborhood Hits	36
SwissProt Accessions	Q8K482	Gene names	Emilin2
Domain Architecture
Description	EMILIN-2 precursor (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Basilin).

NRBP_MOUSE
NC score	0.023660 (rank : 760)	θ value	3.0926 (rank : 307)
Query Neighborhood Hits	451	Target Neighborhood Hits	442	Shared Neighborhood Hits	19
SwissProt Accessions	Q99J45, Q8BL77	Gene names	Nrbp1, Madm, Nrbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor-binding protein (MLF1 adapter molecule) (HLS7- interacting protein kinase).

DCC_HUMAN
NC score	0.023550 (rank : 761)	θ value	8.99809 (rank : 416)
Query Neighborhood Hits	451	Target Neighborhood Hits	583	Shared Neighborhood Hits	45
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

NRBP_HUMAN
NC score	0.023507 (rank : 762)	θ value	3.0926 (rank : 306)
Query Neighborhood Hits	451	Target Neighborhood Hits	448	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UHY1, Q53FZ5, Q96SU3	Gene names	NRBP1, BCON3, NRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor-binding protein.

SOCS7_MOUSE
NC score	0.023394 (rank : 763)	θ value	1.38821 (rank : 239)
Query Neighborhood Hits	451	Target Neighborhood Hits	154	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VHQ2	Gene names	Socs7, Cish7, Nap4
Domain Architecture
Description	Suppressor of cytokine signaling 7 (SOCS-7).

PROP1_MOUSE
NC score	0.023018 (rank : 764)	θ value	4.03905 (rank : 340)
Query Neighborhood Hits	451	Target Neighborhood Hits	361	Shared Neighborhood Hits	19
SwissProt Accessions	P97458	Gene names	Prop1, Prop-1
Domain Architecture
Description	Homeobox protein prophet of Pit-1 (PROP-1) (Pituitary-specific homeodomain factor).

GLUD1_MOUSE
NC score	0.022755 (rank : 765)	θ value	4.03905 (rank : 332)
Query Neighborhood Hits	451	Target Neighborhood Hits	23	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CIX8	Gene names	Gluld1, Lgs
Domain Architecture	No domain graphic available
Description	Glutamate--ammonia ligase domain-containing protein 1 (Lengsin) (Lens glutamine synthase-like).

FOXC1_MOUSE
NC score	0.022581 (rank : 766)	θ value	2.36792 (rank : 271)
Query Neighborhood Hits	451	Target Neighborhood Hits	218	Shared Neighborhood Hits	36
SwissProt Accessions	Q61572, O88409, Q61582	Gene names	Foxc1, Fkh1, Fkhl7, Freac3, Mf1
Domain Architecture
Description	Forkhead box protein C1 (Forkhead-related protein FKHL7) (Forkhead- related transcription factor 3) (FREAC-3) (Transcription factor FKH-1) (Mesoderm/mesenchyme forkhead 1) (MF-1).

ROBO3_MOUSE
NC score	0.022525 (rank : 767)	θ value	0.163984 (rank : 119)
Query Neighborhood Hits	451	Target Neighborhood Hits	524	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Z2I4	Gene names	Robo3, Rbig1
Domain Architecture
Description	Roundabout homolog 3 precursor (Retinoblastoma-inhibiting gene 1) (Rig-1).

PLS4_HUMAN
NC score	0.022270 (rank : 768)	θ value	3.0926 (rank : 308)
Query Neighborhood Hits	451	Target Neighborhood Hits	34	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NRQ2, Q7Z505	Gene names	PLSCR4
Domain Architecture
Description	Phospholipid scramblase 4 (PL scramblase 4) (Ca(2+)-dependent phospholipid scramblase 4) (TRA1).

FOG1_HUMAN
NC score	0.022127 (rank : 769)	θ value	8.99809 (rank : 422)
Query Neighborhood Hits	451	Target Neighborhood Hits	981	Shared Neighborhood Hits	82
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

ACK1_MOUSE
NC score	0.021545 (rank : 770)	θ value	6.88961 (rank : 385)
Query Neighborhood Hits	451	Target Neighborhood Hits	1080	Shared Neighborhood Hits	120
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

DEMA_MOUSE
NC score	0.021423 (rank : 771)	θ value	3.0926 (rank : 294)
Query Neighborhood Hits	451	Target Neighborhood Hits	44	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WV69	Gene names	Epb49, Epb4.9
Domain Architecture
Description	Dematin (Erythrocyte membrane protein band 4.9).

2A5D_HUMAN
NC score	0.021414 (rank : 772)	θ value	1.38821 (rank : 224)
Query Neighborhood Hits	451	Target Neighborhood Hits	59	Shared Neighborhood Hits	9
SwissProt Accessions	Q14738, O00494, O00696, Q15171	Gene names	PPP2R5D
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PP2A, B subunit, B' delta isoform) (PP2A, B subunit, B56 delta isoform) (PP2A, B subunit, PR61 delta isoform) (PP2A, B subunit, R5 delta isoform).

HBS1L_MOUSE
NC score	0.021396 (rank : 773)	θ value	0.62314 (rank : 172)
Query Neighborhood Hits	451	Target Neighborhood Hits	65	Shared Neighborhood Hits	6
SwissProt Accessions	Q69ZS7, Q91Z32, Q9CVT2, Q9CZ95, Q9WTY5	Gene names	Hbs1l, Hbs1, Kiaa1038
Domain Architecture	No domain graphic available
Description	HBS1-like protein.

UBP21_HUMAN
NC score	0.021261 (rank : 774)	θ value	5.27518 (rank : 380)
Query Neighborhood Hits	451	Target Neighborhood Hits	95	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UK80, Q9BTV1, Q9NYN4	Gene names	USP21, USP23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21) (NEDD8-specific protease).

PLCB3_MOUSE
NC score	0.021182 (rank : 775)	θ value	4.03905 (rank : 339)
Query Neighborhood Hits	451	Target Neighborhood Hits	344	Shared Neighborhood Hits	27
SwissProt Accessions	P51432	Gene names	Plcb3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

LTBP4_MOUSE
NC score	0.021034 (rank : 776)	θ value	8.99809 (rank : 427)
Query Neighborhood Hits	451	Target Neighborhood Hits	607	Shared Neighborhood Hits	50
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

FIBB_HUMAN
NC score	0.020992 (rank : 777)	θ value	1.06291 (rank : 204)
Query Neighborhood Hits	451	Target Neighborhood Hits	101	Shared Neighborhood Hits	4
SwissProt Accessions	P02675	Gene names	FGB
Domain Architecture
Description	Fibrinogen beta chain precursor [Contains: Fibrinopeptide B].

CENB1_HUMAN
NC score	0.020914 (rank : 778)	θ value	3.0926 (rank : 292)
Query Neighborhood Hits	451	Target Neighborhood Hits	383	Shared Neighborhood Hits	17
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

Z3H7B_HUMAN
NC score	0.020729 (rank : 779)	θ value	1.81305 (rank : 263)
Query Neighborhood Hits	451	Target Neighborhood Hits	109	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UGR2, Q5TFX9, Q8TBT9, Q9H8B6, Q9UGQ9, Q9UGR0, Q9UGR1, Q9UK03, Q9UPW9	Gene names	ZC3H7B, KIAA1031
Domain Architecture
Description	Zinc finger CCCH-type domain-containing protein 7B (Rotavirus 'X'- associated non-structural protein) (RoXaN).

DEMA_HUMAN
NC score	0.020257 (rank : 780)	θ value	6.88961 (rank : 391)
Query Neighborhood Hits	451	Target Neighborhood Hits	49	Shared Neighborhood Hits	10
SwissProt Accessions	Q08495, Q13215, Q9BRE3	Gene names	EPB49, DMT
Domain Architecture
Description	Dematin (Erythrocyte membrane protein band 4.9).

WNK4_MOUSE
NC score	0.020236 (rank : 781)	θ value	5.27518 (rank : 382)
Query Neighborhood Hits	451	Target Neighborhood Hits	961	Shared Neighborhood Hits	68
SwissProt Accessions	Q80UE6, Q4VAC1, Q80XB5, Q80XN2, Q8R0N0, Q8R340	Gene names	Wnk4, Prkwnk4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

FRM4A_MOUSE
NC score	0.020050 (rank : 782)	θ value	1.06291 (rank : 205)
Query Neighborhood Hits	451	Target Neighborhood Hits	108	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BIE6, Q6PDJ4, Q8CHA6	Gene names	Frmd4a, Frmd4, Kiaa1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

TBCD4_MOUSE
NC score	0.019731 (rank : 783)	θ value	2.36792 (rank : 287)
Query Neighborhood Hits	451	Target Neighborhood Hits	276	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BYJ6, Q5DU23, Q66JU2, Q6P2M2, Q8BMH6, Q8BXM2	Gene names	Tbc1d4, Kiaa0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

CLCN1_HUMAN
NC score	0.018492 (rank : 784)	θ value	2.36792 (rank : 269)
Query Neighborhood Hits	451	Target Neighborhood Hits	89	Shared Neighborhood Hits	22
SwissProt Accessions	P35523	Gene names	CLCN1, CLC1
Domain Architecture
Description	Chloride channel protein, skeletal muscle (Chloride channel protein 1) (ClC-1).

ZN580_MOUSE
NC score	0.018295 (rank : 785)	θ value	0.0148317 (rank : 67)
Query Neighborhood Hits	451	Target Neighborhood Hits	711	Shared Neighborhood Hits	28
SwissProt Accessions	Q9DB38	Gene names	Znf580, Zfp580
Domain Architecture	No domain graphic available
Description	Zinc finger protein 580.

MYT1_MOUSE
NC score	0.018224 (rank : 786)	θ value	8.99809 (rank : 430)
Query Neighborhood Hits	451	Target Neighborhood Hits	385	Shared Neighborhood Hits	24
SwissProt Accessions	Q8CFC2, O08995, Q8CFH1	Gene names	Myt1, Kiaa0835, Nzf2
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1 (MyT1) (Neural zinc finger factor 2) (NZF-2).

PLCB1_MOUSE
NC score	0.017967 (rank : 787)	θ value	8.99809 (rank : 435)
Query Neighborhood Hits	451	Target Neighborhood Hits	531	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Z1B3, Q62075, Q8K5A5, Q8K5A6, Q9Z0E5, Q9Z2T5	Gene names	Plcb1, Plcb
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

CTRO_MOUSE
NC score	0.017645 (rank : 788)	θ value	5.27518 (rank : 355)
Query Neighborhood Hits	451	Target Neighborhood Hits	2344	Shared Neighborhood Hits	114
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

EVX1_MOUSE
NC score	0.017441 (rank : 789)	θ value	0.47712 (rank : 161)
Query Neighborhood Hits	451	Target Neighborhood Hits	350	Shared Neighborhood Hits	15
SwissProt Accessions	P23683	Gene names	Evx1
Domain Architecture
Description	Homeobox even-skipped homolog protein 1 (EVX-1).

DVL2_HUMAN
NC score	0.017381 (rank : 790)	θ value	5.27518 (rank : 360)
Query Neighborhood Hits	451	Target Neighborhood Hits	223	Shared Neighborhood Hits	23
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

CO027_MOUSE
NC score	0.016939 (rank : 791)	θ value	6.88961 (rank : 390)
Query Neighborhood Hits	451	Target Neighborhood Hits	33	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BZB3, Q6NVG3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf27 homolog.

TF3C1_HUMAN
NC score	0.016939 (rank : 792)	θ value	8.99809 (rank : 443)
Query Neighborhood Hits	451	Target Neighborhood Hits	88	Shared Neighborhood Hits	13
SwissProt Accessions	Q12789, Q12838, Q9Y4W9	Gene names	GTF3C1
Domain Architecture	No domain graphic available
Description	General transcription factor 3C polypeptide 1 (Transcription factor IIIC-subunit alpha) (TF3C-alpha) (TFIIIC 220 kDa subunit) (TFIIIC220) (TFIIIC box B-binding subunit).

ZN580_HUMAN
NC score	0.016884 (rank : 793)	θ value	0.279714 (rank : 144)
Query Neighborhood Hits	451	Target Neighborhood Hits	727	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UK33, Q9NPP7	Gene names	ZNF580
Domain Architecture	No domain graphic available
Description	Zinc finger protein 580 (LDL-induced EC protein).

FOXJ3_MOUSE
NC score	0.016718 (rank : 794)	θ value	1.81305 (rank : 252)
Query Neighborhood Hits	451	Target Neighborhood Hits	190	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BUR3, Q3UTD8	Gene names	Foxj3, Kiaa1041
Domain Architecture
Description	Forkhead box protein J3.

RM47_HUMAN
NC score	0.016305 (rank : 795)	θ value	6.88961 (rank : 405)
Query Neighborhood Hits	451	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HD33	Gene names	MRPL47
Domain Architecture
Description	39S ribosomal protein L47, mitochondrial precursor (L47mt) (MRP-L47).

FOXJ3_HUMAN
NC score	0.016265 (rank : 796)	θ value	3.0926 (rank : 297)
Query Neighborhood Hits	451	Target Neighborhood Hits	177	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UPW0, Q9NSS7	Gene names	FOXJ3, KIAA1041
Domain Architecture
Description	Forkhead box protein J3.

NOS3_HUMAN
NC score	0.016097 (rank : 797)	θ value	3.0926 (rank : 305)
Query Neighborhood Hits	451	Target Neighborhood Hits	59	Shared Neighborhood Hits	21
SwissProt Accessions	P29474, Q13662, Q14251, Q14434	Gene names	NOS3
Domain Architecture
Description	Nitric-oxide synthase, endothelial (EC 1.14.13.39) (EC-NOS) (NOS type III) (NOSIII) (Endothelial NOS) (eNOS) (Constitutive NOS) (cNOS).

CTRO_HUMAN
NC score	0.015856 (rank : 798)	θ value	5.27518 (rank : 354)
Query Neighborhood Hits	451	Target Neighborhood Hits	2092	Shared Neighborhood Hits	107
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

DPOLL_HUMAN
NC score	0.015734 (rank : 799)	θ value	5.27518 (rank : 359)
Query Neighborhood Hits	451	Target Neighborhood Hits	26	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UGP5, Q5JQP5, Q6NUM2, Q9HA10, Q9HB35	Gene names	POLL
Domain Architecture
Description	DNA polymerase lambda (EC 2.7.7.7) (EC 4.2.99.-) (Pol Lambda) (DNA polymerase kappa) (DNA polymerase beta-2) (Pol beta2).

CD2L5_MOUSE
NC score	0.015562 (rank : 800)	θ value	8.99809 (rank : 412)
Query Neighborhood Hits	451	Target Neighborhood Hits	1011	Shared Neighborhood Hits	62
SwissProt Accessions	Q69ZA1, Q80V11, Q8BZG1, Q8K0A4	Gene names	Cdc2l5, Kiaa1791
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5).

CAC1E_MOUSE
NC score	0.015352 (rank : 801)	θ value	1.38821 (rank : 227)
Query Neighborhood Hits	451	Target Neighborhood Hits	167	Shared Neighborhood Hits	13
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1E_HUMAN
NC score	0.015332 (rank : 802)	θ value	1.81305 (rank : 247)
Query Neighborhood Hits	451	Target Neighborhood Hits	148	Shared Neighborhood Hits	14
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

ZN687_MOUSE
NC score	0.015216 (rank : 803)	θ value	8.99809 (rank : 451)
Query Neighborhood Hits	451	Target Neighborhood Hits	913	Shared Neighborhood Hits	74
SwissProt Accessions	Q9D2D7, Q6PAP3, Q6ZPQ9	Gene names	Znf687, Kiaa1441, Zfp687
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

SYT6_HUMAN
NC score	0.015013 (rank : 804)	θ value	5.27518 (rank : 379)
Query Neighborhood Hits	451	Target Neighborhood Hits	138	Shared Neighborhood Hits	9
SwissProt Accessions	Q5T7P8	Gene names	SYT6
Domain Architecture	No domain graphic available
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

NPAS2_MOUSE
NC score	0.014751 (rank : 805)	θ value	5.27518 (rank : 369)
Query Neighborhood Hits	451	Target Neighborhood Hits	132	Shared Neighborhood Hits	15
SwissProt Accessions	P97460	Gene names	Npas2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2).

KSR2_HUMAN
NC score	0.014705 (rank : 806)	θ value	1.38821 (rank : 233)
Query Neighborhood Hits	451	Target Neighborhood Hits	920	Shared Neighborhood Hits	64
SwissProt Accessions	Q6VAB6, Q8N775	Gene names	KSR2
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-2 (hKSR2).

NMDE4_MOUSE
NC score	0.014655 (rank : 807)	θ value	5.27518 (rank : 368)
Query Neighborhood Hits	451	Target Neighborhood Hits	158	Shared Neighborhood Hits	30
SwissProt Accessions	Q03391	Gene names	Grin2d
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D).

OST4_HUMAN
NC score	0.014572 (rank : 808)	θ value	5.27518 (rank : 370)
Query Neighborhood Hits	451	Target Neighborhood Hits	95	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y661, Q5QI42, Q8NDC2	Gene names	HS3ST4, 3OST4
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 4 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4) (Heparan sulfate 3-O-sulfotransferase 4) (h3-OST-4).

USP9X_MOUSE
NC score	0.014548 (rank : 809)	θ value	8.99809 (rank : 447)
Query Neighborhood Hits	451	Target Neighborhood Hits	171	Shared Neighborhood Hits	19
SwissProt Accessions	P70398, Q62497	Gene names	Usp9x, Fafl, Fam
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin carboxyl-terminal hydrolase FAM) (Fat facets homolog).

ADAM8_HUMAN
NC score	0.014212 (rank : 810)	θ value	1.06291 (rank : 196)
Query Neighborhood Hits	451	Target Neighborhood Hits	327	Shared Neighborhood Hits	25
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

LTBP2_HUMAN
NC score	0.013741 (rank : 811)	θ value	0.279714 (rank : 138)
Query Neighborhood Hits	451	Target Neighborhood Hits	552	Shared Neighborhood Hits	27
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

PP16A_HUMAN
NC score	0.013603 (rank : 812)	θ value	5.27518 (rank : 373)
Query Neighborhood Hits	451	Target Neighborhood Hits	340	Shared Neighborhood Hits	21
SwissProt Accessions	Q96I34	Gene names	PPP1R16A, MYPT3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase- targeting subunit 3).

MAST3_HUMAN
NC score	0.013520 (rank : 813)	θ value	2.36792 (rank : 275)
Query Neighborhood Hits	451	Target Neighborhood Hits	1128	Shared Neighborhood Hits	79
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

MYH14_MOUSE
NC score	0.013462 (rank : 814)	θ value	5.27518 (rank : 367)
Query Neighborhood Hits	451	Target Neighborhood Hits	1225	Shared Neighborhood Hits	48
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

CC14B_MOUSE
NC score	0.013425 (rank : 815)	θ value	3.0926 (rank : 291)
Query Neighborhood Hits	451	Target Neighborhood Hits	103	Shared Neighborhood Hits	3
SwissProt Accessions	Q6PFY9, Q80WC4, Q8BLV5	Gene names	Cdc14b
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

TNIK_HUMAN
NC score	0.013414 (rank : 816)	θ value	6.88961 (rank : 407)
Query Neighborhood Hits	451	Target Neighborhood Hits	1570	Shared Neighborhood Hits	101
SwissProt Accessions	Q9UKE5, O60298, Q8WUY7, Q9UKD8, Q9UKD9, Q9UKE0, Q9UKE1, Q9UKE2, Q9UKE3, Q9UKE4	Gene names	TNIK, KIAA0551
Domain Architecture
Description	TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1).

CD2L5_HUMAN
NC score	0.013156 (rank : 817)	θ value	1.81305 (rank : 248)
Query Neighborhood Hits	451	Target Neighborhood Hits	987	Shared Neighborhood Hits	55
SwissProt Accessions	Q14004, Q6DKQ9, Q75MH4, Q75MH5, Q96JN4, Q9H4A0, Q9H4A1, Q9UDR4	Gene names	CDC2L5, CDC2L, CHED, KIAA1791
Domain Architecture
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5) (Cholinesterase-related cell division controller).

ATS19_HUMAN
NC score	0.012903 (rank : 818)	θ value	2.36792 (rank : 267)
Query Neighborhood Hits	451	Target Neighborhood Hits	203	Shared Neighborhood Hits	26
SwissProt Accessions	Q8TE59	Gene names	ADAMTS19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

M3K11_HUMAN
NC score	0.012312 (rank : 819)	θ value	8.99809 (rank : 428)
Query Neighborhood Hits	451	Target Neighborhood Hits	1136	Shared Neighborhood Hits	70
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

NF1_HUMAN
NC score	0.012261 (rank : 820)	θ value	8.99809 (rank : 431)
Query Neighborhood Hits	451	Target Neighborhood Hits	56	Shared Neighborhood Hits	4
SwissProt Accessions	P21359, O00662, Q14284, Q14930, Q9UMK3	Gene names	NF1
Domain Architecture
Description	Neurofibromin (Neurofibromatosis-related protein NF-1) [Contains: Neurofibromin truncated].

NF1_MOUSE
NC score	0.012201 (rank : 821)	θ value	8.99809 (rank : 432)
Query Neighborhood Hits	451	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	Q04690, Q61956, Q61957	Gene names	Nf1
Domain Architecture
Description	Neurofibromin (Neurofibromatosis-related protein NF-1).

ACRO_HUMAN
NC score	0.011432 (rank : 822)	θ value	6.88961 (rank : 387)
Query Neighborhood Hits	451	Target Neighborhood Hits	291	Shared Neighborhood Hits	47
SwissProt Accessions	P10323, Q6ICK2	Gene names	ACR, ACRS
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

K2C6B_MOUSE
NC score	0.011098 (rank : 823)	θ value	4.03905 (rank : 334)
Query Neighborhood Hits	451	Target Neighborhood Hits	506	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Z331	Gene names	Krt6b, K6-beta, Krt2-6b
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK 6B) (K6b keratin) (Keratin-6 beta) (mK6-beta).

ZBTB4_HUMAN
NC score	0.010574 (rank : 824)	θ value	5.27518 (rank : 383)
Query Neighborhood Hits	451	Target Neighborhood Hits	926	Shared Neighborhood Hits	48
SwissProt Accessions	Q9P1Z0, Q7Z697, Q86XJ4, Q8N4V8	Gene names	ZBTB4, KIAA1538
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 4 (KAISO-like zinc finger protein 1) (KAISO-L1).

MAK_MOUSE
NC score	0.009864 (rank : 825)	θ value	0.813845 (rank : 190)
Query Neighborhood Hits	451	Target Neighborhood Hits	873	Shared Neighborhood Hits	37
SwissProt Accessions	Q04859	Gene names	Mak, Rck
Domain Architecture
Description	Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male germ cell- associated kinase) (Protein kinase RCK).

DNJC4_MOUSE
NC score	0.009609 (rank : 826)	θ value	5.27518 (rank : 358)
Query Neighborhood Hits	451	Target Neighborhood Hits	79	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D844, O70278	Gene names	Dnajc4, Mcg18
Domain Architecture
Description	DnaJ homolog subfamily C member 4 (Multiple endocrine neoplasia type 1 candidate protein number 18 homolog).

ICK_MOUSE
NC score	0.009350 (rank : 827)	θ value	0.365318 (rank : 150)
Query Neighborhood Hits	451	Target Neighborhood Hits	860	Shared Neighborhood Hits	37
SwissProt Accessions	Q9JKV2, Q8K138	Gene names	Ick
Domain Architecture
Description	Serine/threonine-protein kinase ICK (EC 2.7.11.22) (Intestinal cell kinase) (mICK) (MAK-related kinase) (MRK).

M3K1_MOUSE
NC score	0.008779 (rank : 828)	θ value	3.0926 (rank : 302)
Query Neighborhood Hits	451	Target Neighborhood Hits	952	Shared Neighborhood Hits	42
SwissProt Accessions	P53349, Q60831, Q9R0U3, Q9R256	Gene names	Map3k1, Mekk, Mekk1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1).

CABP4_MOUSE
NC score	0.008019 (rank : 829)	θ value	5.27518 (rank : 351)
Query Neighborhood Hits	451	Target Neighborhood Hits	212	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VHC5	Gene names	Cabp4
Domain Architecture	No domain graphic available
Description	Calcium-binding protein 4 (CaBP4).

HCN1_MOUSE
NC score	0.007799 (rank : 830)	θ value	5.27518 (rank : 363)
Query Neighborhood Hits	451	Target Neighborhood Hits	172	Shared Neighborhood Hits	15
SwissProt Accessions	O88704, O54899, Q9D613	Gene names	Hcn1, Bcng1, Hac2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1) (Hyperpolarization-activated cation channel 2) (HAC-2).

M3K6_HUMAN
NC score	0.007753 (rank : 831)	θ value	6.88961 (rank : 401)
Query Neighborhood Hits	451	Target Neighborhood Hits	889	Shared Neighborhood Hits	41
SwissProt Accessions	O95382	Gene names	MAP3K6, MAPKKK6
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 6 (EC 2.7.11.25).

ICK_HUMAN
NC score	0.007457 (rank : 832)	θ value	5.27518 (rank : 364)
Query Neighborhood Hits	451	Target Neighborhood Hits	867	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UPZ9, O75985, Q5THL2, Q8IYH8, Q9BX17, Q9NYX3	Gene names	ICK, KIAA0936
Domain Architecture
Description	Serine/threonine-protein kinase ICK (EC 2.7.11.22) (Intestinal cell kinase) (hICK) (MAK-related kinase) (MRK) (Laryngeal cancer kinase 2) (LCK2).

DHX29_HUMAN
NC score	0.007171 (rank : 833)	θ value	4.03905 (rank : 329)
Query Neighborhood Hits	451	Target Neighborhood Hits	144	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z478, O75549, Q63HN0, Q63HN3, Q8IWW2, Q8N3A1, Q9UMH2	Gene names	DHX29
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX29 (EC 3.6.1.-) (DEAH box protein 29) (Nucleic acid helicase DDXx).

GDF5_HUMAN
NC score	0.007155 (rank : 834)	θ value	5.27518 (rank : 362)
Query Neighborhood Hits	451	Target Neighborhood Hits	103	Shared Neighborhood Hits	14
SwissProt Accessions	P43026, Q96SB1	Gene names	GDF5, CDMP1
Domain Architecture
Description	Growth/differentiation factor 5 precursor (GDF-5) (Cartilage-derived morphogenetic protein 1) (CDMP-1) (Radotermin).

FBX17_HUMAN
NC score	0.006259 (rank : 835)	θ value	8.99809 (rank : 421)
Query Neighborhood Hits	451	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q96EF6, Q96LQ4	Gene names	FBXO17, FBG4, FBX17, FBX26, FBXO26
Domain Architecture
Description	F-box only protein 17 (F-box only protein 26).

ACOT1_HUMAN
NC score	0.005860 (rank : 836)	θ value	6.88961 (rank : 386)
Query Neighborhood Hits	451	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q86TX2, Q3I5F9	Gene names	ACOT1, CTE1
Domain Architecture	No domain graphic available
Description	Acyl-coenzyme A thioesterase 1 (EC 3.1.2.2) (Acyl-CoA thioesterase 1) (Inducible cytosolic acyl-coenzyme A thioester hydrolase) (Long chain acyl-CoA thioester hydrolase) (Long chain acyl-CoA hydrolase) (CTE-I) (CTE-Ib).

SALL2_HUMAN
NC score	0.005710 (rank : 837)	θ value	8.99809 (rank : 438)
Query Neighborhood Hits	451	Target Neighborhood Hits	835	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y467, Q9Y4G1	Gene names	SALL2, KIAA0360, SAL2
Domain Architecture	No domain graphic available
Description	Sal-like protein 2 (Zinc finger protein SALL2) (HSal2).

MK04_HUMAN
NC score	0.005599 (rank : 838)	θ value	6.88961 (rank : 402)
Query Neighborhood Hits	451	Target Neighborhood Hits	837	Shared Neighborhood Hits	35
SwissProt Accessions	P31152	Gene names	MAPK4, ERK4, PRKM4
Domain Architecture
Description	Mitogen-activated protein kinase 4 (EC 2.7.11.24) (Extracellular signal-regulated kinase 4) (ERK-4) (MAP kinase isoform p63) (p63- MAPK).

SMCA1_HUMAN
NC score	0.005526 (rank : 839)	θ value	8.99809 (rank : 439)
Query Neighborhood Hits	451	Target Neighborhood Hits	105	Shared Neighborhood Hits	11
SwissProt Accessions	P28370, Q5JV41, Q5JV42	Gene names	SMARCA1, SNF2L, SNF2L1
Domain Architecture
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1).

SMCA1_MOUSE
NC score	0.005385 (rank : 840)	θ value	8.99809 (rank : 440)
Query Neighborhood Hits	451	Target Neighborhood Hits	117	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PGB8, Q8BSS1, Q91Y58	Gene names	Smarca1, Snf2l
Domain Architecture	No domain graphic available
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1) (DNA-dependent ATPase SNF2L).

PKN3_HUMAN
NC score	0.004784 (rank : 841)	θ value	5.27518 (rank : 372)
Query Neighborhood Hits	451	Target Neighborhood Hits	893	Shared Neighborhood Hits	41
SwissProt Accessions	Q6P5Z2, Q9UM03	Gene names	PKN3, PKNBETA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

KS6B2_MOUSE
NC score	0.003981 (rank : 842)	θ value	4.03905 (rank : 335)
Query Neighborhood Hits	451	Target Neighborhood Hits	871	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Z1M4	Gene names	Rps6kb2
Domain Architecture
Description	Ribosomal protein S6 kinase beta-2 (EC 2.7.11.1) (S6K-beta 2) (70 kDa ribosomal protein S6 kinase 2) (p70-S6KB) (p70 ribosomal S6 kinase beta) (p70 S6Kbeta) (S6K2).

TNK1_HUMAN
NC score	0.003943 (rank : 843)	θ value	3.0926 (rank : 323)
Query Neighborhood Hits	451	Target Neighborhood Hits	815	Shared Neighborhood Hits	37
SwissProt Accessions	Q13470, O95364, Q8IYI4	Gene names	TNK1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1).

LRP4_HUMAN
NC score	0.003876 (rank : 844)	θ value	3.0926 (rank : 301)
Query Neighborhood Hits	451	Target Neighborhood Hits	355	Shared Neighborhood Hits	7
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

EGR2_MOUSE
NC score	0.002882 (rank : 845)	θ value	0.813845 (rank : 187)
Query Neighborhood Hits	451	Target Neighborhood Hits	745	Shared Neighborhood Hits	29
SwissProt Accessions	P08152	Gene names	Egr2, Egr-2, Krox-20, Zfp-25
Domain Architecture	No domain graphic available
Description	Early growth response protein 2 (EGR-2) (Krox-20 protein).

ZN553_HUMAN
NC score	0.001397 (rank : 846)	θ value	1.81305 (rank : 264)
Query Neighborhood Hits	451	Target Neighborhood Hits	760	Shared Neighborhood Hits	28
SwissProt Accessions	Q96MX3, Q4G0R3, Q69YP3, Q96IL9	Gene names	ZNF553
Domain Architecture	No domain graphic available
Description	Zinc finger protein 553.

ZN579_MOUSE
NC score	0.001256 (rank : 847)	θ value	1.81305 (rank : 265)
Query Neighborhood Hits	451	Target Neighborhood Hits	719	Shared Neighborhood Hits	24
SwissProt Accessions	Q80VM4	Gene names	Znf579, Zfp579
Domain Architecture	No domain graphic available
Description	Zinc finger protein 579.

EGR2_HUMAN
NC score	-0.000532 (rank : 848)	θ value	8.99809 (rank : 418)
Query Neighborhood Hits	451	Target Neighborhood Hits	728	Shared Neighborhood Hits	22
SwissProt Accessions	P11161, Q8IV26, Q9UNA6	Gene names	EGR2, KROX20
Domain Architecture	No domain graphic available
Description	Early growth response protein 2 (EGR-2) (Krox-20 protein) (AT591).

ZNF16_HUMAN
NC score	-0.002744 (rank : 849)	θ value	0.62314 (rank : 180)
Query Neighborhood Hits	451	Target Neighborhood Hits	771	Shared Neighborhood Hits	20
SwissProt Accessions	P17020, Q96FG0	Gene names	ZNF16, KOX9
Domain Architecture	No domain graphic available
Description	Zinc finger protein 16 (Zinc finger protein KOX9).

ZN197_HUMAN
NC score	-0.003383 (rank : 850)	θ value	5.27518 (rank : 384)
Query Neighborhood Hits	451	Target Neighborhood Hits	788	Shared Neighborhood Hits	25
SwissProt Accessions	O14709	Gene names	ZNF197, ZNF166
Domain Architecture
Description	Zinc finger protein 197 (ZnF20).

ZN619_HUMAN
NC score	-0.003845 (rank : 851)	θ value	8.99809 (rank : 450)
Query Neighborhood Hits	451	Target Neighborhood Hits	749	Shared Neighborhood Hits	19
SwissProt Accessions	Q8N2I2	Gene names	ZNF619
Domain Architecture	No domain graphic available
Description	Zinc finger protein 619.